Alphatec Holdings, Inc. Annual Report 2014

FY2014 Annual Report · Alphatec Holdings, Inc.

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Improving lives by delivering advancements
in spinal fusion technologies
Annual Report 2014

www.alphatecspine.com

Dear Valued Shareholders,

2014 was a year of transition for Alphatec Spine where we worked to develop the
foundation necessary to profitably accelerate global growth, improve shareholder value
and expand the number of patients we serve across the world. We delivered solid operating performance for the year and we believe that our outlook
for 2015 has never looked more promising!

Through strong leadership and focus, we were able to deliver full-year 2014 revenues of $207 million – the strongest year of revenue in our history. With
our continued focus on profitability, we also delivered record-level adjusted EBITDA for the year of $30.8 million, representing a 22% improvement over
2013. We were also very pleased to receive clearance in the U.S. for Arsenal™, our newest, innovative spinal fixation system. Arsenal represents the
company’s most significant launch in history and is pivotal for supporting future growth.

In 2014, Alphatec also undertook a planned
leadership transition with the retirement
of Les Cross as Chief Executive Officer in
May. I would like to recognize Les for his
leadership of Alphatec over the past few
years and I look forward to continuing to
work with him as he remains Chairman of
the Board.

(cid:2)(cid:3)(cid:3)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:8)(cid:5)(cid:6)(cid:9)(cid:10)(cid:11)(cid:12)(cid:13)(cid:5)(cid:11)(cid:14)(cid:6)(cid:14)(cid:15)(cid:7)(cid:14)(cid:6)(cid:4)(cid:5)(cid:6)(cid:15)(cid:7)(cid:16)(cid:5)(cid:6)(cid:14)(cid:15)(cid:5)(cid:6)(cid:8)(cid:17)(cid:18)(cid:15)(cid:14)(cid:6)
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(cid:29)(cid:8)(cid:17)(cid:18)(cid:15)(cid:14)(cid:5)(cid:8)(cid:6)(cid:14)(cid:15)(cid:7)(cid:11)(cid:6)(cid:5)(cid:16)(cid:5)(cid:8)(cid:6)(cid:29)(cid:5)(cid:28)(cid:10)(cid:8)(cid:5)(cid:3)(cid:30)

Shortly after I came on board, I began
working with the senior leadership team
to develop a clear strategy – one that is focused on significantly transforming our
company and designed to position us to compete more effectively in the marketplace,
accelerate growth and continue to improve profitability. We refer to this internally as our
“Management Agenda” and this drives our day-to-day decisions and alignment
on priorities across our entire organization. We know we will likely face challenges along the
way, but we are confident that we have the right people, the right strategy and the resources
to make our long-term future brighter than ever before. I am pleased to say that we are fully
underway with executing this strategy.

Our Management Agenda

The objectives of our strategy are centered on accumulation of cash and improving the return
on our invested capital, with our longer term goal of achieving 20% EBITDA margins
within the next three years. To successfully deliver on our objectives, we are
driving execution collectively on the three pillars of our strategy.

(cid:2)(cid:3) Strategic Pillar #1: Refocus our Product Portfolio

and R&D Pipeline to Compete More Effectively

We estimate that the core stabilization and fixation business,
including pedicle screw platforms and interbody systems, represents
approximately $5.5 billion, or two-thirds, of the worldwide spinal fusion
market. To capture a greater portion of this opportunity, we are
focused on innovating and launching differentiated products in these
large market segments of spine. In early 2015, we initiated the full
commercial launch of the Arsenal Degenerative System. We are
also anticipating limited market release launches of:

• Arsenal™ CBX, a less-invasive midline approach for cortical

bone fixation; and

• Battalion™, our new titanium-coated PEEK interbody system.

Looking to the future, we are focusing our R&D resources on two
other large markets of spine:

• Lateral; and

• Deformity

We anticipate launching our lateral and Arsenal Deformity systems in 2016.
Combining the flow of products of today that we’re launching this year
and the programs we have planned through next year, we have a rich
product pipeline – that we believe is one of the
strongest in spine.

(cid:2)(cid:3) Strategic Pillar #2: Expand our Global

Market Participation

As we transform Alphatec in 2015, we are actively increasing our
commercial presence globally with the goal of gaining new surgeon users
for our rich product pipeline. We are rapidly expanding our sales force to
strengthen our coverage:

• U.S.: Expanding coverage across forty major U.S. metropolitan

markets.

• E.U.: Establishing new distributor relationships in eight countries.

We are also expanding our international presence by the introduction of
products:

• Japan: After receiving early approval, we have initiated the launch
of Arsenal in Japan. We are currently third in market share and we
believe this launch will continue to improve our position in this critical
market.

• Brazil: We are currently launching the Zodiac® Degenerative Spinal
Fixation System and Illico® MIS, our minimally invasive system for
posterior fixation solutions.

• China: This also represents a significant market opportunity for us
and we have expectations to expand our presence there during the
year.

We believe that our global expansion combined with our planned
launches in target geographies will allow us to compete more
effectively and gain greater market share.

(cid:2)(cid:3) Strategic Pillar #3: Improve our Manufacturing

and Distribution Operations

In 2014 we continued to make forward strides in our lean excellence
program and will continue that into 2015 and beyond. Additionally, in
2015 we will be focused on improving our overall balance sheet. First,
we have an objective to reduce instrument costs by half over the next
couple of years. To date we have been able to deliver a 50% reduction
in instrument costs for Arsenal. We will be working to apply this cost
reduction expertise across our portfolio. To improve return on invested
capital, we are implementing initiatives designed to transform our
distribution model for instrument sets and double our set turns. Over
time, we believe that achieving these goals will reduce the amount of fixed
assets on our balance sheet, improve our margins and our
free cash flow.

Summary

2015 is expected to be a year of transformation for Alphatec. We will be
focused on executing our strategy:

1) innovating and commercializing products in the large segments of

spine;

2) expanding and deepening our penetration in large, global markets;

and

3) improving profitability through improvements in manufacturing and

our distribution model.

We believe that the combined effect of delivering on these pillars of our
strategy will improve the fundamental quality of our business.

In my first year as President and Chief Executive Officer, I have had the
opportunity to speak with our employees across the world. Regardless
of location, my impression is the same; we have a strong team that is
highly engaged and committed to supporting Alphatec’s future success.
I have also spent time speaking with surgeons in the field and they have
consistently spoken highly of Alphatec’s products and customer service.
This is a great foundation for transformation in
2015 and beyond.

I would like to thank all of my Alphatec colleagues and shareholders
for your continued support and shared commitment in the mission of
Alphatec to help improving lives by delivering advancements in spinal
fusion technology. As I look to the future, I am confident that our strategy
is sound, our employees are aligned and engaged, and I believe we are
uniquely positioned to capture increased share of the spinal fusion market
with our innovative products. 2015 will be an exciting year for us as we
endeavor to deliver greater value to our shareholders and reach more
patients who need spinal fusion around the world.

Sincerely,

James M. Corbett - President and Chief Executive Officer

OUR VALUES

Integrity

» Act ethically and professionally
» Communicate openly and honestly

Customers

» Listen to our customers, understand their needs,

and seek to exceed their expectations

» Deliver innovative, high-quality, easy-to-use

products and solutions

Teamwork

» Help each other by developing effective

partnerships within and outside the company
» Share information and knowledge and treat each

other respectfully

Accountability

» Own your actions and fulfill the commitments you

make

» Establish realistic goals, meet them, and strive to

exceed them

Results

» Take action that delivers value to our stakeholders
» Execute to plan without sacrificing quality

Community

» Contribute to improving quality of life of our
colleagues, our patients and where we live
» Use our resources wisely and minimize waste

www.alphatecspine.com
www.alphatecspine.com

Financial Highlights

(cid:2)(cid:3) Revenue by Region - FY14

$ millions

34%
International

66%

U.S.

69.9

137.1

(cid:2)(cid:3) Revenue and Adjusted EBITDA*

$ millions

196.3

204.7

207.0

19.9

25.2

30.8

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B
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FY12

FY13

FY14

* Adjusted EBITDA is considered non-GAAP financial measures. Adjusted EBITDA reflects net income or loss excluding the effects of interest, taxes, depreciation, amortization, stock-based
compensation, trial-related litigation expenses and other non-recurring items, such as restructuring expenses, IPR&D, legal settlement expenses and transaction related expenses.

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
_________________________________
Form 10-K
_________________________________

(Mark One)

ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934

For the fiscal year ended December 31, 2014

TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934

For the transition period from to

Commission file number: 000-52024
_________________________________

ALPHATEC HOLDINGS, INC.

(Exact Name of Registrant as Specified in its Charter)
_________________________________

Delaware

(State or Other Jurisdiction of
Incorporation or Organization)

5818 El Camino Real, Carlsbad,
California
(Address of Principal Executive Offices)

20-2463898

(I.R.S. Employer
Identification No.)

92008

(Zip Code)

(760) 431-9286
(Registrant’s Telephone Number, Including Area Code)
_________________________________

Securities registered pursuant to Section 12(b) of the Exchange Act:
_________________________________

Title of Each Class
Common Stock, par value $0.0001 per share

Name of Each Exchange on Which Registered
The NASDAQ Global Select Market

Securities registered pursuant to Section 12(g) of the Exchange Act: None
_________________________________

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities

Act. Yes

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15(d) of the Exchange

Act. Yes

Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the
Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to
file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any,

every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12
months (or for such shorter period that the registrant was required to submit and post such files). Yes

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein,
and will not be contained, to the best of the registrant’s knowledge, in definitive proxy or information statements incorporated
by reference in Part III of this Form 10-K or any amendment to this Form 10-K.

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a
smaller reporting company. See definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in
Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer
Non-accelerated filer

(Do not check if a smaller reporting company)

Smaller reporting company

Accelerated filer

Indicate by a check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange

Act). Yes

The aggregate market value of the registrant’s common stock held by non-affiliates of the registrant (without admitting

that any person whose shares are not included in such calculation is an affiliate) computed by reference to the price at which the
common stock was last sold as of the last business day of the registrant's most recently completed second fiscal quarter (June
30, 2014), was approximately $103.6 million.

The number of outstanding shares of the registrant’s common stock, par value $0.0001 per share, as of February 25, 2015

was 99,848,142.

DOCUMENTS INCORPORATED BY REFERENCE
The following documents (or parts thereof) are incorporated by reference into the following parts of this Form 10-K:

Certain information required in Part III of this Annual Report on Form 10-K is incorporated from the Registrant’s Proxy
Statement for the 2015 Annual Meeting of Stockholders.

ALPHATEC HOLDINGS, INC.

FORM 10-K—ANNUAL REPORT
For the Fiscal Year Ended December 31, 2014

Table of Contents

PART I
Item 1.

Item 1A.

Item 1B.

Item 2.

Item 3.

Item 4.

PART II
Item 5.

Item 6.

Item 7.

Item 7A.

Item 8.

Item 9.

Item 9A.

Item 9B.

PART III
Item 10.

Item 11.

Item 12.

Item 13.

Item 14.

PART IV
Item 15.

Business

Risk Factors

Unresolved Staff Comments

Properties

Legal Proceedings

Mine Safety Disclosures

Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity
Securities

Selected Financial Data

Management’s Discussion and Analysis of Financial Condition and Results of Operations

Quantitative and Qualitative Disclosures About Market Risk

Financial Statements and Supplementary Data

Changes in and Disagreements with Accountants on Accounting and Financial Disclosure

Controls and Procedures

Other Information

Directors, Executive Officers and Corporate Governance

Executive Compensation

Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters

Certain Relationships and Related Transactions, and Director Independence

Principal Accounting Fees and Services

Exhibits, Financial Statement Schedules

Page

In this Annual Report on Form 10-K, the terms “we,” “us,” “our,” “Alphatec Holdings” and “Alphatec” mean Alphatec
Holdings, Inc. and our subsidiaries and their subsidiaries. “Alphatec Spine” refers to our wholly-owned operating subsidiary
Alphatec Spine, Inc. “Scient’x” refers to our operating affiliate, Scient’x S.A.S., which is wholly-owned by several of our
subsidiaries, and Scient’x S.A.S.’s subsidiaries.

PART I

Item 1.

Business

Overview

We are a medical technology company focused on the design, development, manufacturing and marketing of products for

Strategy

Our strategy is focused on improving lives by delivering advancements in spinal fusion technologies. Our broad line of

spinal products is used to treat many spinal disorders and facilitate the spinal procedures necessary to correct them. Our
principal products are designed to promote spinal fusion. Spinal fusion surgery is designed to stabilize the spine after the
correction of a defect until fusion occurs. Additionally, we offer a broad line of biologic products that help promote or
accelerate the spinal fusion process. To further differentiate our solutions, we have incorporated minimally invasive surgical, or
MIS, devices and techniques into our portfolio to improve patient outcomes by reducing blood loss and the length of hospital
stays. We seek to broaden and differentiate our product platform through internal product development, technology acquisition,
product licensing and by responding to surgeon feedback and input. We believe that we have developed a strong platform of
spinal fusion products to drive consistent growth.

The key elements of our strategy are:

• Delivering Advancements in Spinal Fusion Technologies: We are dedicated to the development, launch and promotion of

spinal fusion products that simplify procedures and improve patient outcomes. We support these products through
comprehensive surgeon training and technical support. Our short-term and long-term pipeline is designed to offer us
increased revenue opportunities by addressing the core market segments of spinal fusion, including, both open and MIS
pedicle screw systems, interbody devices, cervical plates and a comprehensive biologics offering.

• Focus on Major Segments of the Spinal Fusion Market: Our focus on a spinal fusion platform allows us to reduce the time
of the product development cycle and accelerate our speed to market. We plan to expand our core product offerings and
techniques in the major product segments within the spinal fusion market in order to increase our market penetration and
revenue globally. We also plan to grow our biologics portfolio with products that aid in the fusion process. We intend to
continue to enhance our product offerings by developing, licensing and acquiring technologies that we can market broadly
through our global sales organization. While investing in these opportunities, we remain focused on those technologies
that we believe can enhance spinal fusion and are aligned with our strategy of having a competitive product offering in the
major spinal fusion market segments.

• Grow our U.S. Business: Our products are sold in the U.S. through a network of independent distributors and direct sales
representatives. We actively seek opportunities to increase the size and quality of this sales and distribution network in
order to reach a broader base of surgeons, hospitals, and national accounts across the U.S. and also deepen penetration in
existing accounts and territories.

• Expand our International Business: With recent product approvals in key global markets, we are poised for international
growth. We believe that our well-established international platform provides a strong foundation for us to grow our
business globally. In addition to our established subsidiaries and/or affiliates in Japan, Germany, Brazil, Italy and the
U.K., we also have independent distributors in over 50 countries throughout the world. We plan to continue to increase
our international presence by expanding our distribution network in several key markets in Europe and to increase our
sales penetration in certain other key markets.

• Continuously Drive our Efficiencies and Fiscal Discipline: We continue to focus on the implementation of Lean

Excellence and Six Sigma principles throughout our operations, including our distribution and our supply chain functions,
to drive operational efficiencies and lower costs. We believe that the implementation of these quality management
methods and the resulting continuous improvement efforts strengthen our ability to compete globally in an increasingly
price-sensitive healthcare industry.

Scient'x restructuring

On September 16, 2013, we announced that Scient'x began a process to significantly restructure its business operations in
France in an effort to improve operating efficiencies and rationalize its cost structure. The restructuring included a reduction in
Scient'x's workforce and closing of the manufacturing facilities in France. We recorded total costs of $10.4 million through
December 31, 2014 associated with this restructuring, which includes employee severance, social plan benefits and related
taxes, facility closing costs, manufacturing transfer costs, and contract termination costs. We substantially completed the
activities associated with this restructuring as of December 31, 2014, and a substantial portion has been paid.

Spine Anatomy

The human spine is the core of the human skeleton and provides important structural support while remaining flexible to

allow movement. The human spine is a column of 33 bones that protects the spinal cord and enables people to stand upright.
Each bony segment of the spine is referred to as a vertebra (two or more are called vertebrae). The spine has five regions
containing groups of similar bones, listed from top to bottom: seven cervical vertebrae in the neck, 12 thoracic vertebrae in the
mid-back (each attached to a rib), five lumbar vertebrae in the lower back, five sacral vertebrae fused together to form one bone
in the hip region, and four coccygeal bones fused together that form the tailbone. At the front of each vertebra is a block of
bone called the vertebral body. The vertebral body consists of an inner core of soft cancellous bone, surrounded by a thin outer
layer of hard cortical bone. Vertebrae are stacked on top of each other and enable people to sit and stand upright. Vertebrae in
the cervical, thoracic and lumbar regions are separated from each other and cushioned by a rubbery soft tissue called the
intervertebral disc. Segments of bone that extend outward at the back of each cervical, thoracic and lumbar vertebral body
surround and protect the spinal cord and its nerve roots. These bones, known as the posterior spinous processes, can be felt
along the middle of a person’s back.

Spinal Disorders

We focus on the major categories of the spinal fusion market and address conditions related to spinal degeneration and

deformities. These conditions can result in spinal instability and pressure on the nerve roots as they exit the spinal column,
causing back pain and potentially pain in the arms or legs.

Some of the most common degenerative conditions and deformities affecting the spine are as follows:

• Degenerative disc disease is a common medical condition affecting the cervical, thoracic and lumbar regions of the spine
and refers to the degeneration of the disc from aging and repetitive stresses, resulting in a loss of flexibility, elasticity and
shock-absorbing properties. As degenerative disc disease progresses, the space between the vertebrae narrows, or the disc
can bulge or rupture, which can pinch the nerves exiting the spine and result in back pain, leg pain, numbness and loss of
motor function. This back pain can be overwhelming for patients as the resulting pain can have significant physical,
psychological and financial implications.

•

Spondylolisthesis occurs when one vertebra slips forward in relation to an adjacent vertebra, usually in the lumbar spine.
The symptoms that accompany spondylolisthesis include pain in the lower back and legs, and muscle spasms and
weakness. Spondylolisthesis can be congenital or develop later in life. The disorder may result from physical stresses to
the spine, intense physical activity, and general wear and tear.

Spinal stenosis is a narrowing of the spinal canal, which places pressure on the spinal cord. If the stenosis is located on
the lower part of the spinal cord, it is called lumbar spinal stenosis. Stenosis in the upper part of the spinal cord is called
cervical spinal stenosis. While spinal stenosis can be found in any part of the spine, the lumbar and cervical areas are the
most commonly affected. Some patients are born with this narrowing, but most often spinal stenosis is seen in patients
over the age of 50. In these patients, stenosis is the gradual result of aging and wear and tear on the spine during everyday
activities.

The Alphatec Solution

Our principal product offering includes a wide variety of systems comprised of components such as spine screws and

rods, spinal spacers, plates, and various biologics offerings all designed to enhance and promote spinal fusion. Our business is
focused on treating degenerative and deformity conditions.

The chart below illustrates the principal products in our broad portfolio of spine systems currently available for sale by

market segment. Certain systems and products are described in greater detail below the chart. Items marked with an asterisk are
not available for sale in the U.S.

Current Products:

Market Segment
Cervical and Cervico-thoracic

Thoracolumbar

Spinal Spacers

Minimally Invasive Surgery (MIS)

Biologics

Cervical and Cervico-Thoracic Products

Trestle Luxe Anterior Cervical Plate System

Principal Products
Trestle Anterior Cervical Plate
Trestle Luxe Anterior Cervical Plate
Solanas Posterior Cervico/Thoracic Fixation System
Avalon Occipital Plate
DiscoCerv Artificial Disc*
PCB Evolution*
Arsenal Degenerative Spinal Fixation System
Zodiac Degenerative Fixation System
Zodiac Deformity Fixation System
Illico FS (Facet Screws) Fixation System
TTL IN Fixation System*
Xenon Degenerative Fixation System
Isobar Evolution Dynamic Rod*
Aspida Anterior Lumbar Interbody Plate System
TTL-D Fixation System*
Hemi Fixation System
OsseoFix Spinal Fracture Reduction System*
OsseoFix+ Vertebroplasty System
OsseoScrew Spinal Fixation System*

Novel Spinal Spacers
Alphatec Solus Locking ALIF Spacer
Samarys*/Samarys RF*
Pegasus Anchored Cervical Interbody
HeliFix Interspinous Spacer System*
TeCorp*

Illico MIS System
Illico ML (Multi-Level) MIS Fixation System
OsseoScrew MIS System*
Epicage TLIF System*
BridgePoint Spinous Process Fixation System
AlphaGraft Structural Allograft Spacers
AlphaGraft Demineralized Bone Matrix
AlphaGraft ProFuse Demineralized Bone Scaffolds
AmnioShield Amniotic Membrane
Corex, Autologous Bone Harvester
NEXoss Synthetic Bone Graft

Our Trestle Luxe Anterior Cervical Plate System has a large window that enables the surgeon to have improved graft site

and end plate visualization, which is designed to allow for better placement of the plate. The Trestle Luxe Anterior Cervical
Plate System also has a low-profile design, which we believe is among the lowest in the spine market. Low-profile cervical
plates are intended to reduce the irritation of the tissue adjacent to the plate following surgery. Other key features of the Trestle
Luxe Anterior Cervical Plate system include a self-retaining screw-locking mechanism that is designed to ensure quick and
easy locking of the plate and a flush profile after the screws are inserted.

Solanas Posterior Cervico/Thoracic Fixation System and Avalon Occipital Plate

Our Solanas Posterior Cervico/Thoracic Fixation System consists of rods, polyaxial screws, hooks, and connectors that
provide a solution for posterior cervico/thoracic fusion procedures. We also designed the Solanas Posterior Cervico/Thoracic
System to be used in combination with our existing Zodiac Degenerative Spinal Fixation System and our Avalon Occipital
Plate, thereby providing surgeons with a solution for occipito-cervico-thoracic fixation. The Avalon Occipital Plate has a
unique buttress design for optimal bone graft placement and superior fusion, including three points of plate rotation and
translation, which is designed to ease the placement of the plate.

Thoracolumbar Fixation Products

Arsenal Degenerative System

Our recently introduced Arsenal Degenerative Spinal Fixation System is a comprehensive system for both simple and
complex degenerative spinal fusion procedures. The Arsenal Degenerative Spinal Fixation System was designed to provide
operational efficiency, biomechanical strength, and surgical simplicity while providing a complete solution to combat most
complex degenerative pathologies. We believe the combination of low-profile implants, intuitive instrumentation and proven
strength of this system are significant advantages. The Arsenal Degenerative System was designed to be the platform for future
development in other spinal fusion segments of the market including the deformity, MIS and cervico-thoracic segments of the
market.

Zodiac Degenerative Spinal Fixation System

Our Zodiac Degenerative Spinal Fixation System is a comprehensive spinal system that offers a wide variey of polyaxial

pedicle screws, connector and advanced instruments for the stabilization of the thoracolumbar spine.

Zodiac Deformity Spinal Fixation System
Our Zodiac Deformity Spinal Fixation System is a comprehensive system of instrumentation and implants designed to enable
the surgeon to address patient-specific spinal deformity correction procedures. The Zodiac Deformity Spinal Fixation System
contains polyaxial screws that are similar in design to those in the Zodiac Degenerative Spinal Fixation System. The Zodiac
Deformity Spinal Fixation System offers components that are frequently used in deformity correction procedures and deformity
specific instrumentation.

Aspida Anterior Lumbar Interbody Fusion, or ALIF, Plate System

Our Aspida ALIF Plate System is designed to be used in conjunction with a spacer, and is intended to offer comparable

stabilization to pedicle screw and rod systems. The Aspida ALIF Plate System is anatomically shaped and has a low profile,
which is intended to minimize the risk of irritation or damage to the adjacent tissue.

OsseoScrew Spinal Fixation System

The OsseoScrew Spinal Fixation System is an innovative pedicle screw system that is designed to provide a solution for
patients who have poor bone density. The OsseoScrew System is designed to be implanted into the pedicle and then expanded
after implementation to achieve increased screw fixation in bone with poor density. The OsseoScrew Spinal Fixation System is
not available for sale in the U.S.

Spinal Spacers

Novel PEEK and Titanium Spinal Spacers

Our family of Novel spinal spacers addresses the surgical need to accommodate varying patient anatomies, surgical
approaches and composite material options. We offer multiple unique implant designs, each of which is available in numerous
shapes and heights. Certain of our Novel spinal spacers are made of titanium and others are made of a strong, heat resistant,
radiolucent, biocompatible plastic called polyetheretherketone, or PEEK. Our Novel PEEK spinal spacers have been approved
for use in both the lumbar and cervical regions of the spine. A Novel PEEK spinal spacer is not visible during a magnetic
resonance imaging, which allows the surgeon to better assess the progress of the healing process following surgery. Novel
spacers and their accompanying instrumentation are designed to be inserted from several planes of the body to accommodate
surgeons’ needs. Novel spinal spacers feature sizable central openings that help accommodate the placement of bone grafting

material inside and around the spacer, which we believe promotes fusion. A ridge pattern on the top and bottom of our Novel
spacers helps prevent movement after placement and enhances the stability of the overall construct.

Alphatec Solus Locking ALIF Spinal Spacer

Our Alphatec Solus locking ALIF spinal spacer, or Alphatec Solus, is a zero-profile PEEK and titanium device offering

four points of fixation for improved stability. Alphatec Solus features a one-step insertion and deployment feature and is used in
ALIF procedures. We believe that Alphatec Solus’ locking mechanism is a substantial improvement over similar products
currently on the market.

Samarys

Our Samarys PEEK cervical cage restores disc height as well as cervical lordosis. The cage is anatomically designed for

immediate stability and optimum fusion with a large graft window. Neither Samarys nor Samarys/RF is approved for sale in the
U.S.

Pegasus Anchored Cervical Interbody

The Pegasus Anchored Cervical Interbody, or ACI, System provides surgeons a simplified approach to traditional anterior
cervical disectomy and fusion, or ACDF. It features a single step delivery of a spacer with an integrated anchoring mechanism.
The single-step, non-impaction and locking mechanism reduces operative time and simplifies a standard technique.

MIS Products

Illico Minimally Invasive Surgery System

The Illico Minimally Invasive Surgery System is a cannulated pedicle screw and rod system that is designed to be
inserted via a minimally invasive surgical procedure. Access to the spine is gained through a small incision. The surgeon is then
able to see the surgical site by using a small canal through which implants are inserted into the patient with a minimum amount
of disruption to the surrounding tissue. We believe that the Illico Minimally Invasive System limits trauma to the tissue
surrounding the location of the surgery, which is designed to enable patients to recover faster.

Epicage TLIF System

The Epicage TLIF system addresses the disadvantages of traditional lumbar interbody fusion techniques. The system
incorporates the ease of delivering a bullet-shaped cage and the biomechanically ideal shape of a crescent-shaped cage in a
single implant. Using a unique set of delivery instruments, it accurately establishes the implant's trajectory to consistently
deliver the cage.

BridgePoint Spinous Process Fixation System

The BridgePoint system is a spinous process fixation system that was developed to address the disadvantages of
traditional stabilization devices. The system allows surgeons to fixate the spine using a less invasive approach by attaching a
plate to the spinous process of the vertebral body during spinal fusion surgery.

Biologics

AlphaGraft Structural Allograft Spacers

We offer a broad portfolio of allograft spacers available in a wide range of shapes and sizes, each with corresponding

instrumentation, which are intended for use in the cervical, thoracic, and lumbar regions of the spine. In addition, many of our
allograft spacers are packaged in our VIP packaging system, or VIP System. The VIP System is a packaging and fluid delivery
system that allows for fast and efficient infusion of the surgeon’s choice of hydration fluid. The VIP System provides rapid and
uniform hydration, which may reduce the brittleness of the graft and shorten the length of the surgical procedure.

AlphaGraft ProFuse Demineralized Bone Scaffold

Our AlphaGraft ProFuse Demineralized Bone Scaffold consists of a sponge-like demineralized bone matrix that provides
a natural scaffold derived entirely of bone that can be placed into a void within a spinal spacer or on top of a spinal spacer. The
sponge-like qualities of the scaffold allow a surgeon to compress the scaffold and place it into a small space. Following

placement, the scaffold expands for maximum contact between the spinal spacer and the endplate of the vertebral body and is
designed to promote fusion. The AlphaGraft ProFuse Demineralized Bone Scaffold is pre-packaged in our proprietary VIP
vacuum infusion packaging system.

Amnioshield Amniotic Tissue Barrier

Our Amnioshield Amniotic Tissue Barrier is an allograft for spinal surgical barrier applications. The composite amniotic

membrane reduces inflammation and enhances healing at the surgical site, reduces scar tissue formation and provides an
excellent dissection plane.

Alphagraft Demineralized Bone Matrix

Our Alphagraft Demineralized Bone Matrix consists of demineralized human tissue that is mixed with a bioabsorbable

carrier and intended for use in surgery for bone grafting.

NEXoss Synthetic Bone Graft

Our NEXoss nanostructure bioactive matrix is the next-generation synthetic that is an innovative bioactive scaffold for

bone grafting. The NEXoss biomimetic nanostructured hydroxyapatite crystals are designed to mimic bone composition,
structure and size to resorb similar to naturally occurring hydroxyapatite.

Sales and Marketing

In the U.S., we sell our products through a sales force consisting of sales representative employees and independent sales

agents. Although surgeons in the U.S. typically make the ultimate decision to use our products, we generally bill the hospital
for the products that are used and pay commissions to sales agents based on payment received from the hospital. We
compensate our direct sales employees through salaries and incentive bonuses based on performance measures. We plan on to
expand our U.S. sales coverage through the use of additional distributors and direct sales representatives in order to support
continued adoption of our products by surgeons who do not currently use our products and the increased use of our products by
surgeons who currently use our products.

Internationally, we sell our products both through independent distributors who resell the products to the hospital and

also through distributors and employees that sell directly to the hospital on behalf of the Company. We plan to continue
expanding our direct sales and distribution network and product offerings throughout the world. We market our products at
various international industry conferences, organized surgical training courses, and in industry trade journals and periodicals. In
addition, we host several international educational conferences throughout the world.

We select our sales force based on their expertise in selling spinal devices, reputation within the surgeon community,
geographical coverage and established sales network. We provide product training to our sales force. We market our products at
various industry conferences, organized surgical training courses, and in industry trade journals and periodicals.

Surgeon Training and Education

We focus our surgeon training efforts on the entire spinal fusion procedure and utilize peer to peer training approach with
surgeons. We devote significant resources to train and educate surgeons in the proper use of our implants, instrumentation, and
surgical access technologies. We believe that one of the most effective ways to introduce and build market demand for our
products is by training and educating spine surgeons, independent distributors, and direct sales representatives worldwide in the
benefits and use of our products. Given our global focus, we host several training events throughout the year in the U.S. and
internationally. We believe that surgeons, independent distributors, and direct sales representatives will become exposed to the
merits and distinguishing features of our products through our training and education programs, and in doing so, will increase
the use and promotion of our products. With a focus on the entire procedure, we expect to build awareness of the breadth of our
product offering.

Research and Development

Our research and development department seeks to continually improve our core product offering and introduce new

products to increase our penetration in the global spine market. We are focused on developing technology platforms that span
the largest market segments: spinal fusion fixation and biologic products. We have transformed our development process by
leveraging integrated teams focused on the key platforms to reduce the time frame from product concept to market
commercialization. We collaborate with our surgeon partners to design products to enhance the surgeon experience, simplify
surgical techniques, and reduce overall costs, while improving patient outcomes.

Manufacture and Supply

We manufacture a significant amount of our non-biologic implants in our U.S. facility located in Carlsbad, California.

Certain of our implants and a significant amount of our instrumentation are purchased from third parties. Our facilities include
separate areas dedicated to the machining, tooling, quality control, cleaning and labeling of our products.

We devote significant time and attention to ensure that all of our products are safe, effective, adhere to all applicable

regulations and are of the highest quality. An established and comprehensive quality system drives our focus from the initial
translation of surgeon needs into design specifications through an exhaustive series of quality control checks that are performed
through the purchasing, production and packaging of our products. We record the complete production history for every
product, ensuring full traceability from the raw material stage through the delivery of the product into the marketplace.

Following the receipt of products or product components that we receive from third parties, we conduct inspection,
quality control, packaging and labeling, as needed, at our manufacturing facilities. The raw materials used in the manufacture
of our products are principally titanium, titanium alloys, stainless steel, cobalt chrome, ceramic, allograft and PEEK. We
purchase all of the PEEK used in our products from Invibio, Inc., or Invibio, which is one of a limited number of companies
that is currently approved in the U.S. to distribute PEEK for use in implantable devices.

With the exception of PEEK and tissue-based products, none of our raw material requirements is limited to any

significant extent by critical supply. We are subject to the risk that Invibio will fail to supply PEEK in adequate amounts for our
needs on a timely basis. In addition, because our biologics products are processed from human tissue, maintaining a steady
supply can sometimes be challenging. See our risk factor entitled, “We depend on various third-party suppliers, and in one case
a single third-party supplier, for key raw materials used in our manufacturing processes and the loss of these third-party
suppliers, or their inability to supply us with adequate raw materials, could harm our business” in “Item 1A Risk Factors.” Our
manufacturing operations and those of the third-party manufacturers we use are subject to extensive regulation by the United
States Food and Drug Administration, or "FDA," and similar entities outside of the U.S. under its quality systems regulations,
or QSRs, and other applicable device-related good manufacturing practices, or GMPs, or tissue-related tissue practices, or
GTPs, and applicable local regulations. With respect to biologics products, we are FDA-registered and licensed in the states of
California, New York and Florida, the only states that currently require licenses. Our facility and the facilities of the third-party
manufacturers we use are subject to periodic unannounced inspections by regulatory authorities, and may undergo compliance
inspections conducted by the FDA and corresponding state and foreign agencies.

Competition

Although we believe that our current broad product portfolio and development pipeline is differentiated and has

numerous competitive advantages, the spinal implant industry is highly competitive, subject to rapid technological change, and
significantly affected by new product introductions. We believe that the principal competitive factors in our market include:

•

improved outcomes for spine pathology procedures;

• ease of use, quality and reliability;

• effective and efficient sales, marketing and distribution;

• quality service and an educated and knowledgeable sales network;

•

technical leadership and superiority;

• surgeon services, such as training and education;

•

responsiveness to the needs of surgeons;

• acceptance by spine surgeons;

• product price and qualification for reimbursement; and

• speed to market.

Both our currently marketed products and any future products we commercialize are subject to intense competition. We

believe that our most significant competitors are Medtronic Sofamor Danek, Johnson & Johnson (DePuy/Synthes), Stryker,
Biomet, NuVasive, Zimmer, Orthofix, Globus Medical, Integra Life Science, LDR Spine, K2 Medical and others, many of
which have substantially greater financial resources than we do. In addition, these companies may have more established
distribution networks, entrenched relationships with physicians, and greater experience in developing, launching, marketing,
distributing and selling spinal implant products.

Our competitors also include providers of non-operative therapies for spine disorder conditions. While these non-
operative treatments are considered to be an alternative to surgery, surgery is typically performed in the event that non-

operative treatments are unsuccessful. We believe that, to date, these non-operative treatments have not caused a material
reduction in the demand for surgical treatment of spinal disorders.

Intellectual Property

We rely on a combination of patent, trademark, copyright, trade secret and other intellectual property laws, nondisclosure

agreements, proprietary information ownership agreements and other measures to protect our intellectual property rights. We
believe that in order to have a competitive advantage, we must develop, maintain and enforce the proprietary aspects of our
technologies. We require our employees, consultants, co-developers, distributors and advisors to execute agreements governing
the ownership of proprietary information and use and disclosure of confidential information in connection with their
relationship with us. In general, these agreements require these individuals and entities to agree to disclose and assign to us all
inventions that were conceived on our behalf or which relate to our property or business and to keep our confidential
information confidential and only use such confidential information in connection with our business.

Despite any measures taken to protect our intellectual property, unauthorized parties may attempt to copy aspects of our

products or to obtain and use information that we regard as proprietary. In addition, our competitors may independently develop
similar technologies. Further, as described in “Item 3 Legal Proceedings,” others may attempt to obtain royalties based on the
net sales of our products or other payments from us, which may impact our revenues. We may lose market share to our
competitors if we fail to protect our intellectual property rights.

Patents

As of December 31, 2014, we and our affiliates owned, or exclusively owned 97 issued U.S. patents, 107 pending U.S.

patent applications and 386 issued or pending foreign patents. We own multiple patents relating to unique aspects and
improvements for several of our products. We do not believe that the expiration of any single patent is likely to significantly
affect our intellectual property position.

The medical device industry is characterized by the existence of a large number of patents and frequent litigation based

on allegations of patent infringement. Patent litigation can involve complex factual and legal questions and its outcome is
uncertain. Any claim relating to infringement of patents that is successfully asserted against us may require us to pay
substantial damages (including treble damages if our infringement is found to be willful) or may require us to remove our
infringing product from the market. Even if we were to prevail, any litigation could be costly and time-consuming and would
divert the attention of our management and key personnel from our business operations. Our success will also depend in part on
our not infringing patents issued to others, including our competitors and potential competitors. If our products are found to
infringe the patents of others, our development, manufacture and sale of such potential products could be severely restricted or
prohibited. In addition, our competitors may independently develop similar technologies. We may lose market share to our
competitors if we fail to protect our intellectual property rights.

As the number of entrants into our market increases, the possibility of a patent infringement claim against us grows.

While we make an effort to ensure that our products do not infringe other parties’ patents and proprietary rights, our products
and methods may be covered by U.S. or foreign patents held by our competitors. In addition, our competitors may assert that
future products we may manufacture or market infringe their patents.

If we are accused of patent infringement, we may be required to obtain licenses to patents or proprietary rights of others

in order to continue to commercialize our products. However, we may not be able to obtain any licenses required under any
patents or proprietary rights of third parties on acceptable terms, or at all. Even if we are able to obtain rights to the third party’s
intellectual property, these rights may be non-exclusive, thereby giving our competitors access to the same intellectual property.
Ultimately, we may be unable to commercialize some of our potential products or may have to cease some of our business
operations as a result of patent infringement claims, which could severely harm our business financial condition and results of
operations.

Trademarks

As of December 31, 2014, we and our affiliates owned 69 registered U.S. trademarks, including “Alphatec Spine,”

“Zodiac,” “Illico” and “Trestle Luxe” and 110 registered trademarks outside of the U.S.

Government Regulation

Our products are subject to extensive regulation by the FDA and other U.S. federal and state regulatory bodies and
comparable authorities in other countries. To ensure that medical products distributed domestically and internationally are safe
and effective for their intended use, FDA and comparable authorities in other countries have imposed regulations that govern,
among other things, the following activities that we or our partners perform and will continue to perform:

• product design and development;

• product testing;

• product manufacturing;

• product labeling;

• product storage;

• premarket clearance or approval;

• advertising and promotion;

• product marketing, sales and distribution; and

• post-market surveillance, including reporting deaths or serious injuries related to products and certain product

malfunctions.

FDA’s Premarket Clearance and Approval Requirements

Unless an exemption applies, each medical device we wish to commercially distribute in the U.S. will require either prior
510(k) clearance or approval of a premarket approval application, or PMA. The information that must be submitted to the FDA
in order to obtain clearance or approval to market a new medical device varies depending on how the medical device is
classified by the FDA. Medical devices are classified into one of three classes on the basis of the intended use of the device, the
risk associated with the use of the device for that indication, as determined by the FDA, and on the controls deemed by the
FDA to be necessary to reasonably ensure their safety and effectiveness. Class I devices, which have the lowest level of risk
associated with them, are subject to general controls. Class II devices are subject to general controls and special controls,
including performance standards. Class III devices, which have the highest level of risk associated with them, are subject to
general controls and premarket approval. Most Class I devices and some Class II devices are exempt from the 510(k)
requirement, although the manufacturers will still be subject to establishment registration, medical device listing, labeling
requirements, QSRs and medical device reporting. Class III devices are subject to those requirements and additional
requirements including PMA approval. A new medical device for which there is no substantially equivalent device is
automatically designated a Class III device. Depending on the nature of the new device, the manufacturer may ask the FDA to
make a risk-based determination of the new device and reclassify it in Class I or Class II. This process is referred to as the de
novo process. If the FDA agrees, the new device will be reassigned to the appropriate other class. If the FDA does not agree, the
manufacturer will have to submit a PMA. Our current commercial products are Class II devices marketed under FDA 510(k)
premarket clearance. Both 510(k)s and PMAs are subject to the payment of user fees at the time of submission for FDA review.

510(k) Clearance Pathway

To obtain 510(k) clearance, we must submit a premarket notification demonstrating that the proposed device is
substantially equivalent to a device legally marketed in the U.S. for which a PMA was not required. The FDA’s goal is to
review and act on each 510(k) within 90 days of submission, but it may take longer if the FDA requests additional information.
Most 510(k)s do not require supporting data from clinical trials, but the FDA may request such data.

After a device receives 510(k) clearance, any modification that could significantly affect its safety or effectiveness, or

that would constitute a new or major change in its intended use, will require a new 510(k) clearance or, depending on the
modification, require premarket approval. Each manufacturer initially determines whether the proposed change requires
submission of a 510(k), or a premarket approval, but the FDA can review any such decision and can disagree with a
manufacturer’s determination. If the FDA disagrees with a manufacturer’s determination, the FDA can require the manufacturer
to cease marketing and/or recall the modified device until 510(k) clearance or premarket approval is obtained. If the FDA
requires us to seek a new 510(k) clearance or premarket approval for any modifications to a previously cleared product, we
may be required to cease marketing or recall the modified device until we obtain this clearance or approval. Also, in these
circumstances, we may be subject to significant fines or penalties. We have made and plan to continue to make enhancements
to our products, and we will consider on a case-by-case basis whether a new 510(k) or PMA is necessary.

Premarket Approval Pathway

A PMA must be submitted if the device cannot be cleared through the 510(k) process. The PMA process is generally
more complex, costly and time consuming than the 510(k) process. A PMA must be supported by extensive data including, but
not limited to, technical, preclinical, clinical trials, manufacturing and labeling to demonstrate to the FDA’s satisfaction the
safety and effectiveness of the device for its intended use.

After a PMA is sufficiently complete, the FDA will accept the application for filing and begin an in-depth review of the

submitted information. By statute, the FDA has 180 days to review the accepted application, although, review of the application
generally can take between one and three years. During this review period, the FDA may request additional information or
clarification of information already provided. Also during the review period, an advisory panel of experts from outside the FDA
may be convened to review and evaluate the application and provide recommendations to the FDA as to the approvability of
the device. In addition, the FDA will conduct a preapproval inspection of the manufacturing facility to ensure compliance with
quality system regulations, or QSRs. New premarket approval applications or premarket approval application supplements are
also required for product modifications that affect the safety and efficacy of the device. Premarket approval supplements often
require submission of the same type of information as a PMA, except that the supplement is limited to information needed to
support any changes from the device covered by the original PMA approval, and may not require clinical data or the convening
of an advisory panel. We were not required to submit a PMA for any of our currently marketed products, but devices in
development may require a PMA.

Clinical Trials

Clinical trials are usually required to support a PMA and are sometimes required for a 510(k). In the U.S., if the device is

determined to present a “significant risk,” the manufacturer may not begin a clinical trial until it submits an investigational
device exemption application, or IDE, and obtains approval of the IDE from the FDA. The IDE must be supported by
appropriate data, such as animal and laboratory testing results, showing that it is safe to test the device in humans and that the
testing protocol is scientifically sound. These clinical trials are also subject to the review, approval and oversight of an
institutional review board, or IRB, at each clinical trial site. The clinical trials must be conducted in accordance with the FDA’s
IDE regulations and good clinical practices. A clinical trial may be suspended by FDA, the sponsor or an IRB at any time for
various reasons, including a belief that the risks to the study participants outweigh the benefits of participation in the trial. Even
if a clinical trial is completed, the results may not demonstrate the safety and efficacy of a device to the satisfaction of the FDA,
or may be equivocal or otherwise not be sufficient to obtain approval of a device.

Pervasive and Continuing FDA Regulation

After a device is placed on the market, numerous FDA and other regulatory requirements continue to apply. These

include:

•

quality system regulations, which require manufacturers, including third-party contract manufacturers, to follow stringent
design, testing, control, documentation, record maintenance and other quality assurance controls, during all aspects of the
manufacturing process and to maintain and investigate complaints;

labeling regulations, and FDA prohibitions against the promotion of products for uncleared or unapproved “off-label”
uses;

• medical device reporting obligations, which require that manufacturers submit reports to the FDA of adverse events; and

•

other post-market surveillance requirements, which apply when necessary to protect the public health or to provide
additional safety and effectiveness data for the device.

Failure to comply with applicable regulatory requirements can result in enforcement action by the FDA, which may

include any of the following:

• warning letters;

•

fines, injunctions, and civil penalties;

recall or seizure of products;

operating restrictions, partial suspension or total shutdown of production;

refusal to grant 510(k) clearance or PMA approvals of new products; and

criminal prosecution.

To ensure compliance with regulatory requirements, medical device manufacturers are subject to market surveillance and
manufacturers and their third-party manufacturers are subject to periodic announced and unannounced inspections by the FDA.

Regulation of Human Cells, Tissues, and Cellular and tissue-based Products

Human cells, tissues, and cellular and tissue-based products, or HCT/Ps, are defined as articles containing or consisting of

human cells or tissue that are intended for implantation, transplantation, infusion, or transfer into a human recipient. They are
regulated by the FDA under Section 361 of the Public Health Service Act, or PHS Act, and related regulations promulgated by
the FDA in 21 CFR Part 1271. If the HCT/P is minimally manipulated, is intended for homologous use only and meets other
requirements, the establishment that manufactures the HCT/P will not be regulated as a drug, device and/or biologic under the
Federal Food, Drug and Cosmetic Act, and/or section 351 of the PHS Act and applicable regulations, and premarket review will
not be required.

International Device Regulations

International sales of medical devices are subject to foreign government regulations, which vary substantially from

country to country. The time required to obtain approval by a foreign country may be longer or shorter than that required for
FDA approval, and the requirements may differ.

Japan

In Japan, certain medical devices classified as “highly controlled” must be approved prior to importation and commercial

sale by the Ministry of Health, Labour and Welfare, or MHLW, pursuant to the Japanese Pharmaceutical Affairs Law.
Manufacturers of medical devices outside of Japan which do not operate through a Japanese entity are required to appoint a
contractually bound authorized representative to directly submit an application for device approval to the MHLW. The MHLW
evaluates each device for safety and efficacy and may require that the product be tested in Japanese laboratories. After a device
is approved for importation and commercial sale in Japan, the MHLW continues to monitor sales of approved products for
compliance. Failure to comply with applicable regulatory requirements can result in enforcement action by the MHLW,
including administrative inspections and recommendations; recall or seizure of products; operating restrictions, including
partial suspension or total shut down of marketing activity in Japan; withdrawal of product approvals; and criminal prosecution
by a public prosecutor, including criminal fines and/or imprisonment.

Our devices fall into the “highly controlled” medical device category. Currently, MHLW review times for our device
applications range from one year if clinical data is not required, to up to two years if clinical data is required. The review times
for our products are expected to be reduced to six months and one year, respectively, and we expect application fees to be
reduced as new approval screening standards are established by the MHLW, which has delegated responsibility for these review
functions to the Japanese Pharmaceuticals and Medical Devices Agency, for various medical device categories. Currently, the
MHLW is working with trade organizations such as AdvaMed, and MHLW may adopt similar standards.

European Union

The European Union, which consists of 27 of the countries in Europe, has adopted numerous directives and standards

regulating the design, manufacture, clinical trials, labeling, and adverse event reporting for medical devices. Other countries,
such as Switzerland, have voluntarily adopted laws and regulations that mirror those of the European Union with respect to
medical devices. Devices that comply with the requirements of a relevant directive will be entitled to bear CE conformity
marking and, accordingly, can be commercially distributed throughout the member states of the European Union, as well as
other countries that comply with or mirror these directives. The method of assessing conformity varies depending on the type
and class of the product, but normally involves a combination of self-assessment by the manufacturer or a third-party
assessment by a “Notified Body,” an independent and neutral institution appointed to conduct conformity assessment. This
third-party assessment consists of an audit of the manufacturer’s quality system and technical review and testing of the
manufacturer’s product. An assessment by a Notified Body in one country within the European Union is required in order for a
manufacturer to commercially distribute the product throughout the European Union. In addition, compliance with voluntary
harmonized standards including ISO 13845 issued by the International Organization for Standards establishes the presumption
of conformity with the essential requirements for a CE mark. In October 2007, we were certified by Intertek Semko, a Notified
Body, under the European Union Medical Device Directive allowing the CE conformity marking to be applied. In September
2012, the European Commission adopted a proposed European Medical Device Regulations, or EMDR, which when
implemented will change the way that most medical devices are regulated in the European Union. In particular, the EMDR will
reclassify CE-marked spine implants from Class IIb to Class III, which will impose additional requirements for technical and
clinical information, subject the companies and their suppliers to additional scrutiny and require the use of Special Notified
Bodies.

Environmental Matters

Our facilities and operations are subject to extensive federal, state, and local environmental and occupational health and
safety laws and regulations. These laws and regulations govern, among other things, air emissions; wastewater discharges; the
generation, storage, handling, use and transportation of hazardous materials; the handling and disposal of hazardous wastes; the
cleanup of contamination; and the health and safety of our employees. Under such laws and regulations, we are required to
obtain permits from governmental authorities for some of our operations. If we violate or fail to comply with these laws,
regulations or permits, we could be fined or otherwise sanctioned by regulators. We could also be held responsible for costs and
damages arising from any contamination at our past or present facilities or at third-party waste disposal sites. We cannot
completely eliminate the risk of contamination or injury resulting from hazardous materials, and we may incur material liability
as a result of any contamination or injury.

Compliance with Fraud and Abuse Laws and Other Applicable Statutes

We are subject to various federal and state laws pertaining to healthcare fraud and abuse, including anti-kickback laws,

physician self-referral laws, false claims laws, criminal health care fraud laws, and foreign corrupt practice laws. Violations of
these laws are punishable by criminal and/or civil sanctions, including, in some instances, fines, imprisonment and, within the
United States, exclusion from participation in government healthcare programs, including Medicare, Medicaid and Veterans
Administration health programs. These laws are administered by, among others, the U.S. Department of Justice, the Office of
Inspector General of the Department of Health and Human Services and state attorneys general. Many of these agencies have
increased their enforcement activities with respect to medical device manufacturers in recent years.

The federal Anti-Kickback Statute, prohibits persons from knowingly and willfully soliciting, offering, receiving or
providing remuneration, directly or indirectly, in exchange for or to induce either the referral of an individual, or the furnishing,
arranging for or recommending a good or service, for which payment may be made in whole or part under federal healthcare
programs, such as the Medicare and Medicaid programs. The Anti-Kickback Statute is broad and prohibits many arrangements
and practices that are lawful in businesses outside of the healthcare industry. For example, the definition of “remuneration” has
been broadly interpreted to include anything of value, including, gifts, discounts, the furnishing of supplies or equipment, credit
arrangements, payments of cash, waivers of payments, ownership interests and providing anything at less than its fair market
value. In addition, in March 2010, the U.S. Congress adopted and President Obama signed into law the Patient Protection and
Affordable Health Care Act, which, as amended by the Health Care and Education Reconciliation Act, is referred to as ACA.
ACA, among other things, amends the intent requirement of the federal Anti-Kickback Statute. A person or entity no longer
needs to have actual knowledge of this statute or specific intent to violate it. In addition, ACA provides that the government
may assert that a claim including items or services resulting from a violation of the Anti-Kickback Statute constitutes a false or
fraudulent claim for purposes of the federal False Claims Act.

In implementing the Anti-Kickback Statute, the Office of Inspector General, or OIG, has issued a series of regulations,
known as the safe harbors, which began in July 1991. These safe harbors set forth provisions that, in circumstances where all
the applicable requirements are met, will assure healthcare providers and other parties that they will not be prosecuted under
the Anti-Kickback Statute. The failure of a transaction or arrangement to fit precisely within one or more safe harbors does not
necessarily mean that it is illegal or that prosecution will be pursued. However, conduct and business arrangements that do not
fully satisfy all requirements of an applicable safe harbor may result in increased scrutiny by government enforcement
authorities such as the OIG. Penalties for violations of the Anti-Kickback Statute include criminal penalties and civil sanctions
such as fines, imprisonment and possible exclusion from Medicare, Medicaid and other federal healthcare programs. Many
states have anti-kickback laws that are similar to the federal law, including penalties, fines, sanctions for violations, and
exclusions from state or commercial programs.

The federal ban on physician self-referrals, commonly known as the Stark Law, prohibits, subject to certain exceptions,

physician referrals of Medicare and Medicaid patients to an entity providing certain “designated health services” if the
physician or an immediate family member of the physician has any financial relationship with the entity. Penalties for violating
the Stark Law include fines, civil monetary penalties and possible exclusion from federal healthcare programs. In addition to
the Stark Law, many states have their own self-referral laws. Often, these laws closely follow the language of the federal law,
although they do not always have the same scope, exceptions or safe harbors.

We have entered into various agreements with certain surgeons that perform services for us, including some who make
clinical decisions to use our products. Some of our referring surgeons own our stock, which they either purchased in an arms’
length transaction on terms identical to those offered to non-surgeons or received from us as fair market value consideration for
services performed. All such arrangements have been structured with the intention of complying with all applicable fraud and
abuse laws, including the Anti-Kickback Statute. Stark Law and similar state self-referral laws. In addition, physician-owned
distribution companies, or PODs, have increasingly become involved in the sale and distribution of medical devices, including
products for the surgical treatment of spine disorders. In many cases, these distribution companies enter into arrangements with

hospitals that bill Medicare or Medicaid for the furnishing of medical services, and the physician-owners are among the
physicians who refer patients to the hospitals for surgery. On March 26, 2013 the OIG issued a Special Fraud Alert entitled
"Physician-Owned Entities", or the Fraud Alert, in which the OIG concluded, among other things, that PODs are "inherently
suspect under the anti-kickback statute" and that PODs present "substantial fraud and abuse risk and pose dangers of patient
safety." We believe that all of our arrangements with PODs comply with applicable fraud and abuse laws and do not believe
that we are subject to any arrangements that violate any such laws.

The federal False Claims Act prohibits persons from knowingly filing or causing to be filed a false or fraudulent claim to,

or the knowing use of false statements to obtain payment from, the federal government. Private suits filed under the False
Claims Act, known as qui tam actions, can be brought by individuals on behalf of the government. These individuals,
sometimes known as “relators” or, more commonly, as “whistleblowers,” may share in any amounts paid by the entity to the
government in fines or settlement. The number of filings of qui tam actions has increased significantly in recent years, causing
more healthcare companies to have to defend a False Claim Act action. If an entity is determined to have violated the federal
False Claims Act, it may be required to pay up to three times the actual damages sustained by the government, plus civil
penalties of between $5,500 to $11,000 for each separate false claim and may be subject to exclusion from Medicare, Medicaid
and other federal healthcare programs. Various states have also enacted similar laws modeled after the federal False Claims Act
which apply to items and services reimbursed under Medicaid and other state programs, or, in several states, apply regardless of
the payor.

The Health Insurance Portability and Accountability Act, or HIPAA, created two new federal crimes: healthcare fraud and

false statements relating to healthcare matters. The healthcare fraud statute prohibits knowingly and willfully executing a
scheme to defraud any healthcare benefit program, including private payors. Under recent changes in ACA, the intent
requirement of the healthcare fraud statute is lowered such that a person or entity no longer needs to have actual knowledge of
this statute or specific intent to violate it. A violation of this statute is a felony and may result in fines, imprisonment or possible
exclusion from Medicare, Medicaid and other federal healthcare programs. The false statements statute prohibits knowingly
and willfully falsifying, concealing or covering up a material fact or making any materially false, fictitious or fraudulent
statement in connection with the delivery of or payment for healthcare benefits, items or services. A violation of this statute is a
felony and may result in similar sanctions.

ACA also includes various provisions designed to strengthen significantly fraud and abuse enforcement in addition to

those changes discussed above. Among these additional provisions include increased funding for enforcement efforts and new
“sunshine” provisions to require us to report and disclose to the Centers for Medicare and Medicaid Services, or CMS, any
payment or “transfer of value” made or distributed to physicians or teaching hospitals. These sunshine provisions also require
certain group purchasing organizations, including physician-owned distributors, to disclose physician ownership information to
CMS. On February 8, 2013, CMS published a detailed regulation implementing these sunshine provisions. Under this final
rule, starting August 1, 2013, we and other device manufacturers collected specific data on payments and other transfers of
value to physicians and teaching hospitals for the remaining calendar year 2013, with such data assembled into a report made to
CMS in March 2014. In the fall of 2014, CMS published on its website the partial year 2013 data of all manufacturer reports of
such payments and transfers of value, including those of us. Similar disclosures and CMS reports are to be made annually
thereafter. There are various state laws and initiatives that require device manufacturers to disclose to the appropriate regulatory
agency certain payments or other transfers of value made to physicians, and in certain cases prohibit some forms of these
payments, with the risk of fines for any violation of such requirements. Massachusetts has one of the most stringent of these
laws, and the District of Columbia and Vermont passed such laws in 2008 and 2009, respectively.

HIPAA also includes privacy and security provisions designed to regulate the use and disclosure of “protected health

information” or “PHI” which is health information that identifies a patient and that is held by a health care provider, a health
plan or health care clearinghouse. We are not directly regulated by HIPAA, but our ability to access PHI for purposes such as
marketing, product development, clinical research or other uses is controlled by HIPAA and restrictions placed on health care
providers and other covered entities. HIPAA was amended in 2009 by the Health Information Technology for Economic and
Clinical Health Act (HITECH) which strengthened the rule, increased penalties for violations and added a requirement for the
disclosure of breaches to affected individuals, the government and in some cases the media. We must carefully structure any
transaction involving PHI to avoid violation of HIPAA and HITECH requirements.

Almost all states have adopted data security laws protecting personal information including social security numbers, state
issued identification numbers, credit card or financial account information coupled with individuals’ names or initials. We must
comply with all applicable state data security laws, even though they vary extensively, and must ensure that any breaches or
accidental disclosures of personal information are promptly reported to affected individuals and responsible government
entities. We must also ensure that we maintain compliant, written information security programs or run the risk of civil or even
criminal sanctions for non-compliance as well as reputational harm for publicly reported breaches or violations.

We may also be exposed to liabilities under the U.S. Foreign Corrupt Practices Act, or FCPA, which generally prohibits

companies and their intermediaries from making corrupt payments to foreign officials for the purpose of obtaining or

maintaining business or otherwise obtaining favorable treatment, and requires companies to maintain adequate record-keeping
and internal accounting practices to accurately reflect the transactions of the company. We are also subject to a number of other
laws and regulations relating to money laundering, international money transfers and electronic fund transfers. These laws
apply to companies, individual directors, officers, employees and agents.

If any of our operations are found to have violated or be in violation of any of the laws described above and other
applicable state and federal fraud and abuse laws, we may be subject to penalties, among them being civil and criminal
penalties, damages, fines, exclusion from government healthcare programs, and the curtailment or restructuring of our
operations.

Third-Party Reimbursement

In the U.S., healthcare providers generally rely on third-party payors, principally private insurers and governmental
payors such as Medicare and Medicaid, to cover and pay for all or part of the cost of a spine surgery in which our medical
devices are used. We expect that sales volumes and prices of our products will depend in large part on the continued availability
of reimbursement from such third-party payors. These third-party payors may deny reimbursement if they determine that a
device used in a procedure was not medically necessary in accordance with cost-effective treatment methods, as determined by
the third-party payor, or was used for an unapproved indication. Particularly in the U.S., third-party payors continue to carefully
review, and increasingly challenge, the prices charged for procedures and medical products.

Medicare coverage and reimbursement policies are developed by CMS, the federal agency responsible for administering
the Medicare program, and its contractors. CMS establishes these Medicare policies for medical products and procedures and
such policies are periodically reviewed and updated. While private payors vary in their coverage and payment policies, the
Medicare program is viewed as a benchmark. Medicare payment rates for the same or similar procedures vary due to
geographic location, nature of the facility in which the procedure is performed (i.e., teaching or community hospital) and other
factors. We cannot assure you that government or private third-party payors will cover and provide adequate payment for the
procedures in which our products are used.

ACA and other reform proposals contain significant changes regarding Medicare, Medicaid and other third party payors.

Among these changes was the imposition of a 2.3% excise tax on domestic sales of medical devices that went into effect on
January 1, 2013. These taxes have resulted in a significant increase in the tax burden on our industry. Other elements of this
legislation include numerous provisions to limit Medicare spending through reductions in various fee schedule payments and
by instituting more sweeping payment reforms, such as bundled payments for episodes of care, the establishment of
“accountable care organizations” under which hospitals and physicians will be able to share savings that result from cost
control efforts, comparative effectiveness research, value-based purchasing, and the establishment of an independent payment
advisory board. Many of these provisions have been implemented through the regulatory process. In addition, in June 2012 the
United States Supreme Court upheld the constitutionality of the minimum essential health insurance coverage rule, or so-called
personal mandate, while holding that the federal government must give states the option to accept ACA’s Medical expansion
provisions without risk of losing all federal Medicaid funds. Pursuant to that ruling, several states have declined to expand
Medicaid coverage. For those states, the failure to expand its Medicaid program as prescribed in ACA will restrict the ability of
populations potentially served by such expansion to use our products. Other proposals have been introduced in Congress to
repeal the device tax and various healthcare reform proposals have also emerged at the state level. An expansion in
government’s role in the U.S. healthcare industry may lower reimbursements for our products, reduce medical procedure
volumes, and adversely affect our business and results of operations, possibly materially.

Internationally, healthcare payment systems vary substantially from country to country and include single-payor,

government-managed systems as well as systems in which private payors and government-managed systems exist side-by-side.
Our ability to achieve market acceptance or significant sales volume in international markets we enter will be dependent in
large part on the availability of reimbursement for procedures performed using our products under the healthcare payment
systems in such markets. A small number of countries may require us to gather additional clinical data before covering our
products. It is our intent to complete the requisite clinical studies and obtain coverage in countries where it makes economic
sense to do so.

We believe that the overall escalating cost of medical products and services has led to, and will continue to lead to,

increased pressures on the healthcare industry to reduce the costs of products and services. We cannot assure you that
government or private third-party payors will cover and provide adequate payment for the procedures using our products. In
addition, it is possible that future legislation, regulation, or reimbursement policies of third-party payors will adversely affect
the demand for procedures using our products or our ability to sell our products on a profitable basis. The unavailability or
inadequacy of third-party payor coverage or reimbursement could have a significant adverse effect on our business, operating
results and financial condition.

Employees

As of December 31, 2014, we had approximately 450 employees worldwide in the following areas: sales, customer
service, marketing, clinical education, manufacturing, advanced manufacturing, quality assurance, regulatory affairs, research
and development, human resources, finance, legal, information technology and administration. We have never experienced a
work stoppage due to labor difficulties and believe that our relations with our employees are good. Certain employees in
Europe have labor committees and collective bargaining agreements in place.

Corporate and Available Information

We are a Delaware corporation. We were incorporated in March 2005. Our principal executive office is located at 5818 El

Camino Real, Carlsbad, California 92008. Our Internet address is www.alphatecspine.com. By referring to our website, we do
not incorporate the website or any portion of the website by reference into this Annual Report on Form 10-K. We are not
including the information contained on our website as a part of, or incorporating it by reference into, this Annual Report on
Form 10-K. Our annual reports on Form 10-K, quarterly reports on Form 10-Q, current reports on Form 8-K, and all
amendments to those reports, are available to you free of charge through the Investor Relations section of our website as soon
as reasonably practicable after such materials have been electronically filed with, or furnished to, the Securities and Exchange
Commission, or SEC.

Item 1A. Risk Factors

Investing in our common stock involves a high degree of risk. You should carefully consider the following risk factors and

all other information contained or incorporated by reference in this Annual Report on Form 10-K. The risks and uncertainties
described below are not the only ones facing us. Additional risks and uncertainties that we are unaware of, or that we currently
deem immaterial, also may become important factors that affect us. If any of such risks or the risks described below, either
alone or taken together, occur, our business, financial condition or results of operations could be materially and adversely
affected. In that case, the trading price of our common stock could decline, and you may lose some or all of your investment.

Risks Related to Our Business and Industry

Our business plan relies on certain assumptions pertaining to the market for our products that, if incorrect, may adversely
affect our growth and profitability.

We allocate our design, development, manufacturing, marketing, management and financial resources based on our
business plan, which includes assumptions about various demographic trends and trends in the treatment of spine disorders and
the resulting demand for our products. However, these trends are uncertain. There can be no assurance that our assumptions
with respect to an aging population with broad medical coverage and longer life expectancy, which we expect to lead to
increased spinal injuries and degeneration, are accurate. In addition, an increasing awareness and use of non-invasive means for
the prevention and treatment of back pain and rehabilitation purposes may reduce demand for, or slow the growth of sales of,
spine fusion products. A significant shift in technologies or methods used in the treatment of back pain or damaged or diseased
bone and tissue could adversely affect demand for some or all of our products. For example, pharmaceutical advances could
result in non-surgical treatments gaining more widespread acceptance as a viable alternative to spine fusion. The emergence of
new biological or synthetic materials to facilitate regeneration of damaged or diseased bone and to repair damaged tissue could
increasingly minimize or delay the need for spine fusion surgery and provide other biological alternatives to spine fusion. New
surgical procedures could diminish demand for some of our products. The increased acceptance of emerging technologies that
do not require spine fusion, such as artificial discs and nucleus replacement, for the surgical treatment of spine disorders would
reduce demand for, or slow the growth of sales of, spine fusion products. If our assumptions regarding these factors prove to be
incorrect or if alternative treatments to those offered by our products gain further acceptance, then demand for our products
could be significantly less than we anticipate and we may not be able to achieve or sustain growth or profitability.

If we fail to properly manage our anticipated growth, our business could suffer.

We will continue to pursue growth in, the number of surgeons using our products, the types of products we offer and the

geographic regions where our products are sold. Such anticipated growth has placed and will continue to place significant
demands on our managerial, operational and financial resources and systems. Future growth would impose significant added
responsibilities on members of management, including the need to identify, recruit, maintain, motivate and integrate additional
personnel. Also, our management may need to divert a disproportionate amount of its attention away from our day-to-day
activities and devote a substantial amount of time to managing these anticipated growth activities. We are currently focused on
increasing the size and effectiveness of our sales force and distribution network, marketing activities, research and development
efforts, inventory management systems, management team and corporate infrastructure. If we do not manage our anticipated
growth effectively, the quality of our products, our relationships with physicians, distributors and hospitals, and our reputation
15

could suffer, which would have a significant adverse effect on our business, financial condition and results of operations. We
must attract and retain qualified personnel and third-party distributors and manage and train them effectively. Personnel
qualified in the design, development, production and marketing of our products are difficult to find and hire, and enhancements
of information technology systems to support our growth are difficult to implement. We will also need to carefully monitor and
manage our surgeon services, our manufacturing capabilities, quality assurance and efficiency, and the quality assurance and
efficiency of our suppliers and distributors. This managing, training and monitoring will require allocation of valuable
management resources and significant expense. If our management is unable to effectively manage our expected growth, our
expenses may increase more than expected, our ability to generate and/or grow revenues could be reduced and we may not be
able to implement our business strategy.

We are in a highly competitive market segment, face competition from large, well-established medical device companies with
significant resources, and may not be able to compete effectively.

The market for spine fusion products and procedures is intensely competitive, subject to rapid technological change and

significantly affected by new product introductions and other market activities of industry participants. In 2014, a significant
percentage of global spine implant product revenues was generated by Medtronic Sofamor Danek, a subsidiary of
Medtronic, Inc.; Depuy Spine, a subsidiary of Johnson & Johnson;, and Stryker Spine. Our competitors also include numerous
other publicly-traded and privately-held companies.

Several of our competitors enjoy competitive advantages over us, including:

• more established relationships with spine surgeons;

• more established distribution networks;

•

broader spine surgery product offerings;

stronger intellectual property portfolios;

greater financial and other resources for product research and development, sales and marketing, and patent litigation;

greater experience in, and resources for, launching, marketing, distributing and selling products;

significantly greater name recognition as well as more recognizable trademarks for products similar to the products that
we sell;

• more established relationships with healthcare providers and payors;

•

products supported by more extensive clinical data; and

greater experience in obtaining and maintaining FDA and other regulatory clearances or approvals for products and
product enhancements.

In addition, at any time our current competitors or other companies may develop alternative treatments, products or
procedures for the treatment of spine disorders that compete directly or indirectly with our products, including ones that prove
to be superior to our spine surgery products. For these reasons, we may not be able to compete successfully against our existing
or potential competitors. Any such failure could lead us to modify our strategy, lower our prices, increase the commissions we
pay on sales of our products and have a significant adverse effect on our business, financial condition and results of operations.

We have incurred and expect to incur costs and charges as a result of the restructuring of our French operations and
workforce reductions that we expect will reduce on-going costs, and those measures also may be disruptive to our business and
may not result in anticipated cost savings.

A significant percentage of our revenues are derived from the sale of our systems that include polyaxial pedicle screws.

Net sales of our systems that include polyaxial pedicle screws represented approximately 49% and 47% of our net sales
for 2014 and 2013, respectively. A decline in sales of these systems, due to lower market demand, the introduction by a third
party of a competitive product, an intellectual property dispute involving these systems, or otherwise, would have a significant
adverse impact on our business, financial condition and results of operations. Some of the technology related to our polyaxial
pedicle screw systems is licensed to us. Any action that would prevent us from manufacturing, marketing and selling our
polyaxial pedicle screw systems would have a significant adverse effect on our business, financial condition and results of
operations.

Our sales and marketing efforts in the U.S. are largely dependent upon third parties, some of which are free to market
products that compete with our products.

Certain of our independent distributors in the U.S. also market and sell the products of our competitors, and those

competitors may have the ability to influence the products that our independent distributors choose to market and sell. Our
competitors may be able, by offering higher commission payments or otherwise, to convince our independent distributors to
terminate their relationships with us, carry fewer of our products or reduce their sales and marketing efforts for our products.

We may be unable to accurately predict future sales through distributors that purchase products directly from us, which
could harm our ability to forecast sales performance.

A portion of our sales are made through domestic and international third-party distributors that purchase our products

directly from us and then resell such products to hospitals. As a result, our financial results, quarterly product sales, trends and
comparisons are affected by fluctuations in the buying patterns and inventory levels of these distributors. While we attempt to
assist such distributors in forecasting its future sales and maintaining adequate inventory levels, we may not be consistently
accurate or successful. In addition, our distributors’ decision-making process regarding orders is complex and involves several
factors, including surgeon demand levels, which can make it difficult to accurately predict our sales until late in a quarter. Our
failure to accurately forecast sales through distributors that purchase products directly from us and the failure of such
distributors to maintain adequate inventory levels could lead to a decline in sales and adversely affect our results of operations.

If pricing pressures cause us to decrease prices for our goods and services and we are unable to compensate for such
reductions through changes in our product mix or reductions to our expenses, our results of operations will suffer.

We may experience decreasing prices for our goods and services we offer due to pricing pressure exerted by our
customers in response to increased cost containment efforts from managed care organizations and other third-party payors and
increased market power of our customers as the medical device industry consolidates. If we are unable to offset such price
reductions through changes in our product mix or reductions in our expenses, our business, financial condition, results of
operations and cash flows will be adversely affected.

We conduct a significant amount of our sales activity outside of the U.S., which subjects us to additional business risks and
may adversely affect our results of operations and financial condition.

During the year ended December 31, 2014, we derived $69.9 million, or 34% of our net sales from sales of products
outside of the U.S. We intend to continue to pursue growth opportunities in sales internationally, which could expose us to
additional risks associated with international sales and operations. Our international operations are, and will continue to be,
subject to a number of risks and potential costs, including:

• changes in foreign medical reimbursement policies and programs;

• changes in foreign regulatory requirements;

• differing local product preferences and product requirements;

• diminished protection of intellectual property in some countries outside of the U.S.;

• differing payment cycles;

•

trade protection measures and import or export licensing requirements;

• difficulty in staffing, training and managing foreign operations;

• differing legal requirements and labor relations;

• potentially negative consequences from changes in tax laws (including potentially taxes payable on earnings of foreign

subsidiaries upon repatriation); and

• political and economic instability.

In addition, we are subject to risks arising from currency exchange rate fluctuations, which could decrease our revenues,

increase our costs and may adversely affect our results of operations. Significant increases in the value of the U.S. dollar
relative to foreign currencies could have a material adverse effect on our international results of operations.

To be commercially successful, we must convince the spine surgeon community that our products are an attractive
alternative to our competitors’ products. If the spine surgeon community does not use our products, our sales will decline
and we will be unable to increase our sales and profits.

In order for us to sell our products, surgeons must be convinced that they are superior to competing products. Acceptance

of our products depends on educating the spine surgeon community as to the distinctive characteristics, perceived benefits,
safety and cost-effectiveness of our products compared to our competitors’ products and on training surgeons in the proper
application of our products. If we are not successful in convincing the spine surgeon community of the merit of our products,
our sales will decline and we will be unable to increase or achieve and sustain growth or profitability.

There is a learning process involved for spine surgeons to become proficient in the use of our products. Although most

spine surgeons may have adequate knowledge on how to use most of our products based on their clinical training and
experience, we believe that the most effective way to introduce and build market demand for our products is by directly
training spine surgeons in the use of our products. If surgeons are not properly trained, they may misuse or ineffectively use our
products. This may also result in unsatisfactory patient outcomes, patient injury, negative publicity or lawsuits against us, any
of which could have a significant adverse effect on our business, financial condition and results of operations.

We must retain the current distributors of our products and attract new distributors of our products.

As we launch new products and increase our marketing efforts with respect to existing products, we will need to expand

our sales and marketing organization. We plan to accomplish this by increasing our network of independent distributors and
hiring additional direct sales representatives. The establishment and development of a broader sales network and dedicated
sales force may be expensive and time consuming. Because of the intense competition for their services, we may be unable to
recruit or retain additional qualified independent distributors and to hire additional direct sales representatives to work with us.
Often, our competitors enter into distribution agreements with independent distributors that require such distributors to
exclusively sell the products of our competitors. Further, we may not be able to enter into agreements with independent
distributors on commercially reasonable terms, if at all. Even if we do enter into agreements with additional independent
distributors, it often takes 90 to 120 days for new distributors to reach full operational effectiveness and such distributors
may not generate revenue as quickly as we expect them to, commit the necessary resources to effectively market and sell our
products or ultimately be successful in selling our products. Our business, financial condition and results of operations will be
materially adversely affected if we do not retain our existing independent distributors and attract new, additional independent
distributors or if the marketing and sales efforts of our independent distributors and our own direct sales representatives are
unsuccessful.

We may not be successful in manufacturing products at the levels required to meet future market demand.

We are seeking to grow sales of our products and if we are successful, such growth may strain our ability to manufacture

an increasingly large supply of our products. We have never produced products in quantities significantly in excess of our
current production levels. Manufacturers regularly experience difficulties in scaling up production and we may face such
difficulties in increasing our production levels. Moreover, we may not be able to manufacture our products with consistent and
satisfactory quality or in sufficient quantities to meet demand. Our failure to produce products of satisfactory quality or in
sufficient quantities could hurt our reputation; cause hospitals, surgeons or distributors to cancel orders or refrain from placing
new orders for our products; and reduce or slow growth of sales of our products. Increases in our production volume also could
make it harder for us to maintain control over expenses, manage our relationships with our suppliers, maintain good relations
with our employees or otherwise manage our business. In addition, should we not be able to achieve our revenue forecast and
cash consumption starts to exceed forecasted consumption, management will need to adjust our production of surgical
instruments and manage our inventory to the decreased sales volumes. If we do not make these adjustments in a timely manner,
there could be an adverse impact on our financial resources.

We depend on various third-party suppliers, and in one case a single third-party supplier, for key raw materials used in our
manufacturing processes and the loss of any of these third-party suppliers, or their inability to supply us with adequate raw
materials, could harm our business.

We use a number of raw materials, including titanium, titanium alloys, stainless steel, PEEK, and human tissue. We rely

from time to time on a number of suppliers and in one case on a single source vendor, Invibio. We have a supply agreement
with Invibio, pursuant to which it supplies us with PEEK, a biocompatible plastic that we use in some of our spacers. Invibio is
one of a limited number of companies approved to distribute PEEK in the U.S. for use in implantable devices. During both
2014 and 2013, approximately 16% of our revenues were derived from products manufactured using PEEK.

We depend on a limited number of sources of human tissue for use in our biologics products, and any failure to obtain

tissue from these sources or to have the tissue processed by these entities for us in a timely manner will interfere with our
ability to meet demand for our biologics products effectively. The processing of human tissue into biologics products is labor
intensive and it is therefore difficult to maintain a steady supply stream. In addition, due to seasonal changes in mortality rates,
some scarce tissues used for our biologics products are at times in particularly short supply. We cannot be certain that our
supply of human tissue from our current suppliers and our current inventory of biologics products will be available at current
levels or will be sufficient to meet our needs.

Our dependence on a single third-party PEEK supplier and the challenges we may face in obtaining adequate supplies of
biologics products involve several risks, including limited control over pricing, availability, quality and delivery schedules. In
addition, any supply interruption in a limited or sole sourced component or raw material, such as PEEK or human tissue, could
materially harm our ability to manufacture our products until a new source of supply, if any, could be found. We may be unable
to find a sufficient alternative supply channel in a reasonable time period or on commercially reasonable terms, if at all, which
would have a significant adverse effect on our business, financial condition and results of operations.

Our tissue-based products and related technologies could become subject to significantly greater regulation by the FDA,
which could disrupt our business.

The FDA may regulate certain tissue-based products as medical devices, drugs or biologics if the tissue in the product is

deemed to have been more than minimally manipulated or does not meet other requirements. If the FDA decides that any of our
current or future products contain tissue that has been more than minimally manipulated or that it does not meet other
requirements, it would require us to obtain either 510(k) clearance or a PMA approval. If this were to happen, further
distribution of the affected products could be interrupted for a substantial period of time, which would reduce our revenues and
hurt our profitability.

Negative publicity concerning methods of tissue recovery and screening of donor tissue in our industry could reduce
demand for biologics products and impact the supply of available donor tissue.

Media reports or other negative publicity concerning both alleged improper methods of tissue recovery from donors and

disease transmission from donated tissue could limit widespread acceptance of biologics products. Unfavorable reports of
improper or illegal tissue recovery practices, both in the U.S. and internationally, as well as incidents of improperly processed
tissue leading to the transmission of disease, may broadly affect the rate of future tissue donation and market acceptance of
biologics products. In addition, such negative publicity could cause the families of potential donors to become reluctant to
agree to donate tissue to for-profit tissue processors, which could further limit the supply of tissue used in our biologics
products, and thereby have a negative effect on our biologics products business.

If we or our suppliers fail to comply with the FDA’s quality system and good tissue practice regulations, the manufacture of
our products could be delayed.

We and our suppliers are required to comply with the FDA’s QSRs, which cover, among other things, the methods and

documentation of the design, testing, production, control, quality assurance, labeling, packaging, sterilization, record keeping,
storage and shipping of our products. In addition, suppliers and processors of products derived from human cells and tissues
must comply with the FDA’s current good tissue practice regulations, or CGTPs, which govern the methods used in and the
facilities and controls used for the manufacture of human cell tissue and cellular products, record keeping and the establishment
of a quality program. The FDA audits compliance with the QSRs and CGTPs through inspections of manufacturing and other
facilities. If we or our suppliers have significant non-compliance issues or if any corrective action plan is not sufficient, we or
our suppliers could be forced to halt the manufacture of our products until such problems are corrected to the FDA’s
satisfaction, which could have a material adverse effect on our business, financial condition and results of operations. Further,
our products could be subject to recall if the FDA determines, for any reason, that our products are not safe or effective. Any
recall or FDA requirement demanding that we seek additional approvals or clearances could result in delays, costs associated
with modification of a product, loss of revenue and potential operating restrictions imposed by the FDA, all of which could
have a material adverse effect on our business, financial condition and results of operations.

Healthcare policy changes, including recent federal legislation to reform the U.S. healthcare system, may have a material
adverse effect on us.

In response to perceived increases in health care costs in recent years, there have been and continue to be proposals by

the federal government, state governments, regulators and third-party payors to control these costs and, more generally, to
reform the U.S. healthcare system. Certain of these proposals could limit the prices we are able to charge for our products or

the amounts of reimbursement available for our products, limit the acceptance and availability of our products, and have a
material adverse effect on our financial position and results of operations.

In March 2010, the U.S. Congress adopted and President Obama signed into law the ACA. The legislation imposes a
2.3% excise tax on domestic sales of medical devices which went into effect on January 1, 2013. These taxes are resulting in a
significant increase in the tax burden on our industry. Other elements of this legislation include numerous provisions to limit
Medicare spending through reductions in various fee schedule payments and by instituting more sweeping payment reforms,
such as bundled payments for episodes of care, the establishment of “accountable care organizations” under which hospitals
and physicians will be able to share savings that result from cost control efforts, comparative effectiveness research, value-
based purchasing, and the establishment of an independent payment advisory board. Many of these provisions have been
implemented through the regulatory process with most of the legislation implemented as of January 1, 2014. In addition,
although ACA has been subject to various legal and legislative challenges, in June 2012 the United States Supreme Court
upheld the constitutionality of the minimum essential health insurance coverage rule, or so-called personal mandate, while
holding that the federal government must give states the option to accept ACA’s Medical expansion provisions without risk of
losing all federal Medicaid funds. Pursuant to that ruling, several states have declined to expand Medicaid coverage. For those
states, the failure to expand its Medicaid program as prescribed in ACA will restrict the ability of populations potentially served
by such expansion to use our products. Other proposals have been introduced in Congress to repeal the device tax, and various
healthcare reform proposals have also emerged at the state level. An expansion in government’s role in the U.S. healthcare
industry may lower reimbursements for our products, reduce medical procedure volumes and adversely affect our business and
results of operations, possibly materially.

The demand for our products and the prices at which customers and patients are willing to pay for our products depend
upon the ability of our customers to obtain adequate third-party coverage and reimbursement for their purchases of our
products.

Sales of our products depend in part on the availability of adequate coverage and reimbursement from governmental and

private payors. In the U.S., healthcare providers that purchase our products generally rely on third-party payors, principally
Medicare, Medicaid and private health insurance plans, to pay for all or a portion of the costs and fees associated with the use
of our products. In addition, several million individuals were able to purchase health insurance in 2014 for the first time
through health insurance "exchanges" established under the ACA. Many of these individuals were assisted in paying these
premiums by federal tax subsidies made available under the ACA. While our currently marketed products are eligible for
reimbursement in the U.S., if surgical procedures utilizing our products are performed on an outpatient basis, it is possible that
private payors may no longer provide reimbursement for our products without further supporting data on our procedure. Any
delays in obtaining, or an inability to obtain, adequate coverage or reimbursement for procedures using our products could
significantly affect the acceptance of our products and have a significant adverse effect on our business. Additionally, third-
party payors continue to review their coverage policies carefully for existing and new therapies and can, without notice, deny
coverage for treatments that include the use of our products. In the current term ending in June 2015, the U.S. Supreme Court
will rule in a case on the question whether the federal government may continue to make subsidized payments to support health
insurance premiums to certain qualified individuals if they purchase their insurance on a health insurance exchange established
by the federal government when a state has chosen not to establish its own exchange as is the case with 34 states. A ruling by
the Court that such subsidy payments may only be made to individuals purchasing health insurance on exchanges established
by states could call into question the ability of many individuals in these 34 states, which have not established state exchanges,
to continue to afford to purchase health insurance, and thereby limit a key goal of the ACA to expand health care coverage. Our
business would be negatively impacted to the extent any such changes reduce reimbursement for our products.

With respect to coverage and reimbursement outside of the U.S., reimbursement systems in international markets vary

significantly by country, and by region within some countries, and reimbursement approvals must be obtained on a country-by-
country basis and can take up to 18 months, or longer. Many international markets have government-managed healthcare
systems that govern reimbursement for new devices and procedures. In most markets, there are private insurance systems as
well as government-managed systems. Additionally, some foreign reimbursement systems provide for limited payments in a
given period and therefore result in extended payment periods. Reimbursement in international markets may require us to
undertake country-specific reimbursement activities, including additional clinical studies, which could be time consuming,
expensive and may not yield acceptable reimbursement rates.

Furthermore, healthcare costs have risen significantly over the past decade. There have been and may continue to be
proposals by legislators, regulators and third-party payors to contain these costs. Several such proposals were enacted as part of
ACA, and include numerous provisions to limit Medicare spending through reductions in various fee schedule payments and
sweeping payment reforms. Other federal and state cost-control measures include prospective payment systems, capitated rates,
group purchasing, redesign of benefits, requiring pre-authorizations or second opinions prior to major surgery, encouragement
of healthier lifestyles and exploration of more cost-effective methods of delivering healthcare. Some healthcare providers in the

U.S. have adopted or are considering a managed care system in which the providers contract to provide comprehensive
healthcare for a fixed cost per person. Healthcare providers may also attempt to control costs by authorizing fewer elective
surgical procedures or by requiring the use of the least expensive devices possible. These cost-control methods also potentially
limit the amount which healthcare providers may be willing to pay for medical devices. In addition, in the U.S., no uniform
policy of coverage and reimbursement for medical technology exists among all these payors. Therefore, coverage of and
reimbursement for medical technology can differ significantly from payor to payor. The continuing efforts of third-party
payors, whether governmental or commercial, whether inside or outside the U.S., to contain or reduce these costs, combined
with closer scrutiny of such costs, could restrict our customers’ ability to obtain adequate coverage and reimbursement from
these third-party payors. The cost containment measures contained in ACA and other measures being considered at the federal
and state level, as well as internationally, could harm our business by adversely affecting the demand for our products or the
price at which we can sell our products.

Consolidation in the healthcare industry could lead to demands for price concessions or to the exclusion of some suppliers
from certain of our markets, which could have an adverse effect on our business, financial condition or results of
operations.

Because healthcare costs have risen significantly over the past decade, numerous initiatives and reforms initiated by
legislators, regulators and third-party payors to curb these costs have resulted in a consolidation trend in the healthcare industry
to create new companies with greater market power, including hospitals. As the healthcare industry consolidates, competition to
provide products and services to industry participants has become and will continue to become more intense. This in turn has
resulted and will likely continue to result in greater pricing pressures and the exclusion of certain suppliers from important
market segments as group purchasing organizations, independent delivery networks and large single accounts continue to use
their market power to consolidate purchasing decisions for some of our customers. We expect that market demand, government
regulation, third-party reimbursement policies and societal pressures will continue to change the worldwide healthcare industry,
resulting in further business consolidations and alliances among our customers, which may reduce competition, exert further
downward pressure on the prices of our products and may adversely impact our business, financial condition or results of
operations.

We may be subject to or otherwise affected by federal and state healthcare laws, including fraud and abuse, health
information privacy and security, and disclosure laws, and could face substantial penalties if we are unable to fully comply
with such laws.

Although we do not provide healthcare services, submit claims for third-party reimbursement, or receive payments

directly from Medicare, Medicaid, or other third-party payors for our products or the procedures in which our products are
used, healthcare regulation by federal and state governments significantly impacts our business. Healthcare fraud and abuse,
health information privacy and security, and disclosure laws potentially applicable to our operations include:

•

the federal Anti-Kickback Statute, as well as state analogs, which constrains our marketing practices and those of our
independent sales agents and distributors, educational programs, pricing policies, and relationships with healthcare
providers by prohibiting, among other things, knowingly and willfully soliciting, receiving, offering or providing
remuneration, intended to induce the purchase or recommendation of an item or service reimbursable under a federal (or
state or commercial) healthcare program (such as the Medicare or Medicaid programs);

the federal ban, as well as state analogs, on physician self-referrals, which prohibits, subject to certain exceptions,
physician referrals of Medicare and Medicaid patients to an entity providing certain “designated health services” if the
physician or an immediate family member of the physician has any financial relationship with the entity;

federal false claims laws which prohibit, among other things, knowingly presenting, or causing to be presented, claims for
payment from Medicare, Medicaid, or other third-party payors that are false or fraudulent;

• HIPAA, and its implementing regulations, which created federal criminal laws that prohibit executing a scheme to defraud

any healthcare benefit program or making false statements relating to healthcare matters;

•

the state and federal laws “sunshine” provisions that require detailed reporting and disclosures to CMS and made
available on CMS's website starting in the fall of 2014, and applicable states of any payments or “transfer of value” made
or distributed to prescribers and other health care providers, and for certain states prohibit some forms of these payments,
require the adoption of marketing codes of conduct, and constrain their relationships with physicians and other referral
sources;

•

state laws analogous to each of the above federal laws, such as anti-kickback and false claims laws that may apply to
items or services reimbursed by any third-party payor, including commercial insurers, and state laws governing the
privacy of certain health information, many of which differ from each other in significant ways and often are not
preempted by HIPAA, thus complicating compliance efforts;

the Administrative Simplification provisions of HIPAA, specifically, privacy and security provisions including recent
amendments under HITECH which impose stringent restrictions on uses and disclosures of protected health information
such as for marketing or clinical research purposes and impose significant civil and criminal penalties for non-compliance
and require the reporting of breaches to affected individuals, the government and in some cases the media in the event of
a violation; and

a variety of state-imposed privacy and data security laws which require the protection of information beyond health
information, such as employee information or any class of information combining name with state issued identification
numbers, social security numbers, credit card, bank or other financial information and which require reporting to state
officials in the event of breach or violation and which impose both civil and criminal penalties.

ACA includes various provisions designed to strengthen significantly fraud and abuse enforcement, such as increased

funding for enforcement efforts and the lowering of the intent requirement of the federal Anti-Kickback Statute and criminal
healthcare fraud statute such that a person or entity no longer needs to have actual knowledge of these statutes or specific intent
to violate them.

If our past or present operations, or those of our independent sales agents and distributors are found to be in violation of

any of such laws or any other governmental regulations that may apply to us, we may be subject to penalties, including civil
and criminal penalties, damages, fines, exclusion from federal healthcare programs and/or the curtailment or restructuring of
our operations. Similarly, if the healthcare providers, sales agents, distributors or other entities with which we do business are
found to be non-compliant with applicable laws, they may be subject to sanctions, which could also have a negative impact on
us. Any penalties, damages, fines, curtailment or restructuring of our operations could adversely affect our ability to operate our
business and our financial results. The risk of our being found in violation of these laws is increased by the fact that many of
them have not been fully interpreted by the regulatory authorities or the Courts, and their provisions are open to a variety of
interpretations. Any action against us for violation of these laws, even if we successfully defend against them, could cause us to
incur significant legal expenses and divert our management’s attention from the operation of our business.

In January 2004, the Advanced Medical Technology Association, or AdvaMed, the principal U.S. trade association for the

medical device industry, put in place a model “code of conduct”, or the AdvaMed Code, that sets forth standards by which its
members should abide in the promotion of their products. Although we are not a member of AdvaMed, we have in place
policies and procedures for compliance that we believe are at least as stringent as those set forth in the AdvaMed Code, and we
provide routine training to our sales and marketing personnel on our policies regarding sales and marketing practices.

The sales and marketing practices of our industry have been the subject of increased scrutiny from federal and state
government agencies, and we believe that this trend will continue. For example, on March 26, 2013 the OIG issued a Special
Fraud Alert entitled "Physician-Owned Entities" related to physician-owned distributors, or PODS. We believe that all of our
arrangements with PODs comply with applicable fraud and abuse laws and do not believe that we are subject to any
arrangements that violate any such laws. Prosecutorial scrutiny and governmental oversight over some major device companies
regarding the retention of healthcare professionals as consultants has affected and may continue to affect the manner in which
medical device companies may retain healthcare professionals as consultants. We have in place policies to govern how we may
retain healthcare professionals as consultants that reflect the current climate on this issue and are providing training on these
policies. Any action against us for violation of these laws, even if we successfully defend against them, could cause us to incur
significant legal expenses and divert our management’s attention from the operation of our business.

Our international operations may expose us to liabilities under the Foreign Corrupt Practices Act and Money Laundering
Laws.

We may be exposed to liabilities under the U.S. Foreign Corrupt Practices Act, or FCPA, which generally prohibits
companies and their intermediaries from making corrupt payments to foreign officials for the purpose of obtaining or keeping
business or otherwise obtaining favorable treatment, and requires companies to maintain adequate record keeping and internal
accounting practices to accurately reflect the transactions of the company. We are also subject to a number of other laws and
regulations relating to money laundering, international money transfers and electronic fund transfers, which we collectively
refer to as Money Laundering Laws. These laws apply to companies, individual directors, officers, employees and agents.

We operate in a number of jurisdictions with developing economies that pose a high risk of potential violations of the

FCPA and Money Laundering Laws, and we utilize third-party distributorships that have government customers. If our
employees, third-party distributors or other agents are found to have engaged in practices that violate the FCRA or money

laundering laws, we could suffer severe penalties, including criminal and civil penalties, disgorgement and other remedial
measures, any of which could have a material adverse effect on our business, financial condition and results of operations.

If we fail to obtain, or experience significant delays in obtaining, FDA clearances or approvals for our future products or
modifications to our products, our ability to commercially distribute and market our products could suffer.

Our medical devices are subject to extensive regulation by the FDA and numerous other federal, state and foreign
governmental authorities. The process of obtaining regulatory clearances or approvals to market a medical device, particularly
from the FDA, can be costly and time consuming, and there can be no assurance that such clearances or approvals will be
granted on a timely basis, if at all. In particular, the FDA permits commercial distribution of most new medical devices only
after the devices have received clearance under Section 510(k) of the Federal Food, Drug and Cosmetic Act, or 510(k), or are
the subject of an approved premarket approval application, or a PMA. The 510(k) process generally takes three to nine months,
but can take significantly longer, especially if the FDA requires a clinical study to support the 510(k) application. Currently, we
do not know whether the FDA will require clinical data in support of any 510(k)s that we intend to submit for other products in
our pipeline. In addition, the FDA is currently re-examining its 510(k) clearance process for medical devices and published
several draft guidance documents that could change that process. Any changes that make the process more restrictive could
increase the time it takes for us to obtain clearances or could make the 510(k) process unavailable for certain of our products. A
PMA must be submitted to the FDA if the device cannot be cleared through the 510(k) process or is not exempt from premarket
review by the FDA. A PMA must be supported by extensive data, including results of preclinical studies and clinical trials,
manufacturing and control data and proposed labeling, to demonstrate to the FDA’s satisfaction the safety and effectiveness of
the device for its intended use. The PMA process is more costly and uncertain than the 510(k) clearance process, and generally
takes between one and three years, if not longer. In addition, any modification to a 510(k)-cleared device that could
significantly affect its safety or effectiveness, or that would constitute a major change in its intended use, design or
manufacture, requires a new 510(k) clearance or, possibly, a PMA.

Our commercial distribution and marketing of any products or product modifications that we develop will be delayed
until regulatory clearance or approval is obtained. In addition, because we cannot assure you that any new products or any
product modifications we develop will be subject to the shorter 510(k) clearance process, the regulatory approval process for
our new products or product modifications may take significantly longer than anticipated. There is no assurance that the FDA
will not require a new product or product modification to go through the lengthy and expensive PMA approval process. Delays
in obtaining regulatory clearances and approvals may:

• delay or prevent commercialization of products we develop;

•

require us to perform costly tests or studies;

• diminish any competitive advantages that we might otherwise have obtained; and

•

reduce our ability to collect revenues.

To date, all of our non-biologic medical device products that have required FDA review that are being sold in the U.S.

have been cleared through the 510(k) process without any required clinical trials. However, the FDA may require clinical data
in support of any future 510(k)s or PMAs that we intend to submit for products in our pipeline. We have limited experience in
performing clinical trials that might be required for a 510(k) clearance or PMA approval. If any of our products require clinical
trials, the commercialization of such products could be delayed which could have a material adverse effect on our business,
financial condition and results of operations.

The safety of our products is not yet supported by long-term clinical data and may therefore prove to be less safe and
effective than initially thought.

We obtained clearance to offer all of our current non-biologic medical device products through the 510(k) route. The
ability to obtain a 510(k) clearance is generally based on the FDA’s agreement that a new product is substantially equivalent to
certain already marketed products. Because most 510(k)-cleared products were not the subject of pre-clearance clinical trials,
surgeons may be slow to adopt our 510(k)-cleared products, we may not have the comparative data that our competitors have or
are generating, and we may be subject to greater regulatory and product liability risks. With the passage of the American
Recovery and Reinvestment Act of 2009, funds have been appropriated for the U.S. Department of Health and Human
Services’ Healthcare Research and Quality to conduct comparative effectiveness research to determine the effectiveness of
different drugs, medical devices, and procedures in treating certain conditions and diseases. Some of our products or procedures
performed with our products could become the subject of such research. It is unknown what effect, if any, this research may
have on our business. Further, future research or experience may indicate that treatment with our products does not improve
patient outcomes or improves patient outcomes less than we initially expect. Such results would reduce demand for our
products and this could cause us to withdraw our products from the market. Moreover, if future research or experience indicate

that our products cause unexpected or serious complications or other unforeseen negative effects, we could be subject to
significant legal liability, significant negative publicity, damage to our reputation and a dramatic reduction in sales of our
products, all of which would have a material adverse effect on our business, financial condition and results of operations.

Due to the anticipated regulatory pathway, we do not anticipate commercializing certain products in the U.S.

Several of our products are not available for sale in the U.S., due to the anticipated regulatory path that is required to sell

such product in the U.S. Prior to such products being sold in the U.S. we anticipate that the FDA will require submission of
either a 510(k) with clinical trial data or a PMA. As a result, to receive regulatory clearance or approval in the U.S. for
OsseoScrew, we must conduct, at our own expense, a clinical trial to demonstrate efficacy and safety in humans. Clinical trials
are expensive and have an uncertain outcome. In addition, clinical failure can occur at any stage of the testing. As a result, we
do not anticipate ever selling such products in the U.S.

If we choose to acquire new and complementary businesses, products or technologies, we may be unable to complete these
acquisitions or successfully integrate them in a cost-effective and non-disruptive manner.

Our success depends in part on our ability to continually enhance and broaden our product offering in response to
changing customer demands, competitive pressures and technologies and our ability to increase our market share. Accordingly,
we have pursued and intend to pursue the acquisition of complementary businesses, products or technologies instead of
developing them ourselves. We do not know if we will be able to successfully complete any acquisitions, or whether we will be
able to successfully integrate any acquired business, product or technology into our business or retain any key personnel,
suppliers or distributors. Our ability to successfully grow through acquisitions depends upon our ability to identify, negotiate,
complete and integrate suitable acquisitions and to obtain any necessary financing. These efforts could be expensive and time
consuming, disrupt our ongoing business and distract management. If we are unable to integrate any future or recently acquired
businesses, products or technologies effectively, our business, financial condition and results of operations will be materially
adversely affected. For example, an acquisition could materially impair our operating results by causing us to incur debt or
requiring us to amortize significant amounts of expenses, including non-cash acquisition costs, and acquired assets.

We may not be able to timely develop new products or product enhancements that will be accepted by the market.

We sell our products in a market that is characterized by technological change, product innovation, evolving industry

standards, competing patent claims, patent litigation and intense competition. Our success will depend in part on our ability to
develop and introduce new products and enhancements or modifications to our existing products, which we will need to do
before our competitors do so and in a manner that does not infringe issued patents of third parties from which we do not have a
license. We cannot assure you that we will be able to successfully develop or market new, improved or modified products, or
that any of our future products will be accepted by even the surgeons who use our current products. Our competitors’ product
development capabilities could be more effective than our capabilities, and their new products may get to market before our
products. In addition, the products of our competitors may be more effective or less expensive than our products. The
introduction of new products by our competitors may lead us to have price reductions, reduced margins or loss of market share
and may render our products obsolete or noncompetitive. The success of any of our new product offerings or enhancement or
modification to our existing products will depend on several factors, including our ability to:

• properly identify and anticipate surgeon and patient needs;

• develop new products or enhancements in a timely manner;

• obtain the necessary regulatory approvals for new products or product enhancements;

• provide adequate training to potential users of new products;

•

receive adequate reimbursement approval of third-party payors such as Medicaid, Medicare and private insurers; and

• develop an effective marketing and distribution network.

Developing products in a timely manner can be difficult, in particular because product designs change rapidly to adjust to

third-party patent constraints and to market preferences. As a result, we may experience delays in our product launches which
may significantly impede our ability to enter or compete in a given market and may reduce the sales that we are able to
generate from these products. We may experience delays in any phase of a product launch, including during research and
development, clinical trials, manufacturing, marketing and the surgeon training process. In addition, our suppliers of products
or components that we do not manufacture can suffer similar delays, which could cause delays in our product introductions. If
we do not develop new products or product enhancements in time to meet market demand or if there is insufficient demand for
these new products or enhancements, it could have a significant adverse effect on our business financial condition and results of
operations.

We are dependent on our senior management team, sales and marketing team, engineering team and key surgeon advisors,
and the loss of any of them could harm our business.

Our continued success depends in part upon the continued availability and contributions of our senior management, sales
and marketing team and engineering team and the continued participation of our key surgeon advisors. While we have entered
into employment agreements with all members of our senior management team, none of these agreements guarantees the
services of the individual for a specified period of time. We would be adversely affected if we fail to adequately prepare for
future turnover of our senior management team. Our ability to grow or at least maintain our sales levels depends in large
part on our ability to attract and retain sales and marketing personnel and for these sales people to maintain their relationships
with surgeons directly and through our distributors. We rely on our engineering team to research, design and develop potential
products for our product pipeline. We also rely on our surgeon advisors to advise us on our products, our product pipeline,
long-term scientific planning, research and development and industry trends. We compete for personnel and advisors with other
companies and other organizations, many of which are larger and have greater name recognition and financial and other
resources than we do. The loss of members of our senior management team, sales and marketing team, engineering team and
key surgeon advisors, or our inability to attract or retain other qualified personnel or advisors, could have a significant adverse
effect on our business, financial conditions and results of operations.

Security breaches, loss of data and other disruptions could compromise sensitive information related to our business,
prevent us from accessing critical information or expose us to liability, which could adversely affect our business and our
reputation.

In the ordinary course of our business, we collect and store sensitive data, including legally protected patient health
information, credit card information, personally identifiable information about our employees, intellectual property, and
proprietary business information. We manage and maintain our applications and data utilizing on-site systems. These
applications and data encompass a wide variety of business critical information including research and development
information, commercial information and business and financial information.

The secure processing, storage, maintenance and transmission of this critical information is vital to our operations and
business strategy, and we devote significant resources to protecting such information. Although we take measures to protect
sensitive information from unauthorized access or disclosure, our information technology and infrastructure may be vulnerable
to attaches by hackers; viruses, breaches or interruptions due to employee error or malfeasance, terrorist attacks, earthquakes,
fire, flood, other natural disasters, power loss, computer systems failure, data network failure, Internet failure, or lapses in
compliance with privacy and security mandates. Any such virus, breach or interruption could compromise our networks and the
information stored there could be accessed by unauthorized parties, publicly disclosed, lost or stolen. We have measures in
place that are designed to detect and respond to such security incidents and breaches of privacy and security mandates. Any
such access, disclosure or other loss of information could result in legal claims or proceedings, liability under laws that protect
the privacy of personal information, such as HIPAA, government enforcement actions and regulatory penalties. Unauthorized
access, loss or dissemination could also interrupt our operations, including our ability to bill our customers, provide customer
support services, conduct research and development activities, process and prepare company financial information, manage
various general and administrative aspects of our business and damage our reputation, any of which could adversely affect our
business.

The majority of our operations and all of our manufacturing facilities are currently conducted in locations that may be at
risk of damage from fire, earthquakes or other natural disasters. If a natural disaster strikes, we may be unable to
manufacture certain products for a substantial amount of time.

We currently conduct the majority of our development, manufacturing and management activities in Carlsbad, California

near known wildfire areas and earthquake fault zones. We have taken precautions to safeguard our facilities, including
obtaining property and casualty insurance, and implementing health and safety protocols. We have developed an information
technology disaster recovery plan. However, any future natural disaster, such as a fire or an earthquake, could cause substantial
delays in our operations, damage or destroy our equipment or inventory and cause us to incur additional expenses. A disaster
could seriously harm our business, financial condition and results of operations. Our facilities would be difficult to replace and
would require substantial lead time to repair or replace. The insurance we maintain against earthquakes, fires, and other natural
disasters would not be adequate to cover a total loss of our manufacturing facilities, may not be adequate to cover our losses in
any particular case and may not continue to be available to us on acceptable terms, or at all.

Alphatec Holdings is a holding company with no operations, and unless it receives dividends or other payments from its
subsidiaries, it will be unable to fulfill its cash obligations.

As a holding company with no business operations, Alphatec Holdings’ material assets consist only of the common stock

of its subsidiaries, including Alphatec Spine and Scient’x, dividends and other payments received from time to time from its
subsidiaries, and the proceeds raised from the sale of debt and equity securities. Alphatec Holdings’ subsidiaries are legally
distinct from Alphatec Holdings and have no obligation, contingent or otherwise, to make funds available to Alphatec
Holdings. Alphatec Holdings will have to rely upon dividends and other payments from its subsidiaries to generate the funds
necessary to fulfill its cash obligations. Alphatec Holdings may not be able to access cash generated by its subsidiaries in order
to fulfill cash commitments. The ability of Alphatec Spine to make dividend and other payments to Alphatec Holdings is
subject to the availability of funds after taking into account its subsidiaries’ funding requirements, the terms of its subsidiaries’
indebtedness and applicable state laws.

Compliance with changing regulations and standards for accounting, corporate governance and public disclosure may
result in additional expenses.

Changing laws, regulations and standards relating to corporate governance and public disclosure, including the Sarbanes-

Oxley Act of 2002, new SEC regulations, including accelerated SEC filing timelines and new proxy rules, new NASDAQ
Stock Market rules, and new accounting pronouncements create uncertainty and additional complexities for companies such as
ours. In particular, the Section 404 internal control evaluation requirements under the Sarbanes-Oxley Act have added and will
continue to add complexity and costs to our business and require a significant investment of our time and resources to complete
each year. We take these requirements seriously and will make every effort to ensure that we receive clean attestations on our
internal controls each year from our outside auditors, but there is no guarantee that our efforts to do so will be successful. To
maintain high standards of corporate governance and public disclosure, we intend to invest all reasonably necessary resources
to comply with all other evolving standards. These investments may result in increased general and administrative expenses and
a diversion of management time and attention from strategic revenue generating and cost management activities.

If we fail to maintain effective internal controls and procedures for financial reporting, we could be unable to provide
timely and accurate financial information and therefore be subject to delisting from The NASDAQ Global Select Market, an
investigation by the SEC, and civil or criminal sanctions. Additionally, ineffective internal control over financial reporting
would place us at increased risk of fraud or misuse of corporate assets and could cause our stockholders, lenders, suppliers and
others to lose confidence in the accuracy or completeness of our financial reports.

Risks Related to Our Financial Results and Need for Financing

Our quarterly financial results could fluctuate significantly.

Our quarterly financial results are difficult to predict and may fluctuate significantly from period to period, particularly
because our sales prospects are uncertain. The level of our revenues and results of operations at any given time will be based
primarily on the following factors:

• acceptance of our products by surgeons, patients, hospitals and third-party payors;

• demand and pricing of our products;

•

the mix of our products sold, because profit margins differ among our products;

timing of new product offerings, acquisitions, licenses or other significant events by us or our competitors;

• our ability to grow and maintain a productive sales and marketing organization;

•

regulatory approvals and legislative changes affecting the products we may offer or those of our competitors;

the effect of competing technological and market developments;

levels of third-party reimbursement for our products;

interruption in the manufacturing or distribution of our products;

• our ability to produce or obtain products of satisfactory quality or in sufficient quantities to meet demand; and

• changes in our ability to obtain FDA, state and international approval or clearance for our products.

In addition, until we have a larger base of surgeons using our products, occasional fluctuations in the use of our products

by individual surgeons or small groups of surgeons will have a proportionately larger impact on our revenues than for
companies with a larger customer base.

Many of the products we may seek to develop and introduce in the future will require FDA, state and international
approval or clearance. We cannot begin to commercialize any such products in the U.S. without FDA approval or clearance or
outside of the U.S. without appropriate regulatory approvals and import licenses. As a result, it will be difficult for us to
forecast demand for these products with any degree of certainty. We cannot assure you that our revenue will increase or be
sustained in future periods or that we will be profitable in any future period. Any shortfalls in revenue or earnings from levels
expected by our stockholders or by securities or industry analysts could have an immediate and significant adverse effect on the
trading price of our common stock in any given period.

We may need to raise additional funds in the future and such funds may not be available on acceptable terms, if at all.

We believe that our current cash, revenues from our operations, and Alphatec Spine’s ability to draw down on its credit
facilities, will be sufficient to fund our projected operating requirements through December 31, 2015. Despite this belief, we
may seek additional funds from public and private equity or debt financings, borrowings under new debt facilities or other
sources. Our capital requirements will depend on many factors, including:

•

the payments due in connection with the settlement of the Cross Medical and Orthotec matters;

the revenues generated by sales of our products;

the costs associated with expanding our sales and marketing efforts;

the expenses we incur in manufacturing and selling our products;

the costs of developing new products or technologies;

the cost of obtaining and maintaining FDA or other regulatory approval or clearance for our products and products in
development;

the number and timing of acquisitions and other strategic transactions;

the costs and any payments we may make related to our pending litigation matters (in addition to the Orthotec matter);

the costs associated with increased capital expenditures; and

the costs associated with our employee retention programs and related benefits.

As a result of these factors, we may need to raise additional funds and such funds may not be available on favorable

terms, if at all. Furthermore, if we issue equity or debt securities to raise additional funds, our existing stockholders
may experience dilution and the new equity or debt securities may have rights, preferences and privileges senior to those of our
existing stockholders. In addition, if we raise additional funds through collaboration, licensing or other similar arrangements, it
may be necessary to relinquish valuable rights to our potential products or proprietary technologies, or to grant licenses on
terms that are not favorable to us. If we cannot raise funds on acceptable terms, we may not be able to develop or enhance our
products, execute our business plan, take advantage of future opportunities, or respond to competitive pressures or
unanticipated customer requirements. Any of these events could adversely affect our ability to achieve our development and
commercialization goals and have a significant adverse effect on our business, financial condition and results of operations.

We may be unable to comply with the covenants of our credit facilities.

We must comply with certain affirmative and negative covenants, including financial covenants, in our credit facility with

MidCap Financial, LLC, or the Credit Facility and affirmative and negative covenants in our credit facility with Deerfield, or
Facility Agreement. In order to comply with the financial covenants for 2015, we will need to achieve revenue and earnings
that meet or exceed our historical revenue and earnings levels. If we are not able to achieve planned revenue or earnings growth
or if we incur costs in excess of our forecast, we may be required to substantially reduce discretionary spending and could be in
default of the Credit Facility. In addition to financial covenants, the Credit Facility also contains customary affirmative and
negative covenants for loan agreements of this type, including, but not limited to, limitations on the incurrence of indebtedness,
asset dispositions, acquisitions, investments, dividends and other restricted payments, liens and transactions with affiliates, the
breach of which could result in an event of default. There can be no assurance that at all times in the future we will satisfy all
such financial or other covenants or obtain any required waiver or amendment, in which event of default the lenders party to
the Credit Facility could refuse to make further extensions of credit to us and require all amounts borrowed under the Credit
Facility, together with accrued interest and other fees, to be immediately due and payable. In addition to allowing the lenders to
accelerate the loan, several events of default under the Credit Facility, such as our failure to make required payments of
principal and interest and the occurrence of certain bankruptcy or insolvency events, could require us to pay interest at a rate
which is up to five percentage points higher than the interest rate effective immediately before the event of default.

An event of default under the Credit Facility or the Facility Agreement could have a material adverse effect on us. Upon

an event of default, if the lenders under the Credit Facility accelerate the repayment of all amounts borrowed, together with
accrued interest and other fees, or if the lenders elect to charge us additional interest, we cannot assure you that we will have
sufficient cash available to repay the amounts due, and we may be forced to seek to amend the terms of the Credit Facility or
the Facility Agreement or obtain alternative financing, which may not be available to us on acceptable terms, if at all.

In addition, if we fail to pay amounts when due under the Credit Facility or the Facility Agreement or upon the

occurrence of another event of default, the lenders under the Credit Facility or the Facility Agreement could proceed against the
collateral granted to them pursuant to the Credit Facility and the Facility Agreement. We have granted to the lenders under the
Credit Facility a first priority security interest in substantially all of our assets, including all accounts receivable and all
securities evidencing our interests in our subsidiaries, as collateral under the Credit Facility. If the lenders proceed against the
collateral, such assets would no longer be available for use in our business, which would have a significant adverse effect our
business, financial condition and results of operations.

If we default on our obligations to make settlement payments to Cross Medical Products or Orthotec LLC, the amounts due
under the settlement agreements accelerates and becomes due and payable.

Any default of our payment obligation under the settlement agreements we entered into with Cross Medical Products, or

Cross, or Orthotec would give Cross or Orthotec the right to declare all of the future payments to be immediately payable,
together with additional payments to cover interest and Cross’ legal fees. As of February 25, 2015, the outstanding amount to
be paid to Cross Medical through August 2015 is $2.0 million and the outstanding amount to be paid to Orthotec through
January 2024 is $39.2 million. If either acceleration of payments occurs, our business, financial condition and results of
operations could be materially and adversely affected.

Risks Related to Our Intellectual Property Regulatory Penalties and Potential Litigation

If our patents and other intellectual property rights do not adequately protect our products, we may lose market share to our
competitors and be unable to operate our business profitably.

Our success depends significantly on our ability to protect our proprietary rights of the technologies used in our products.

We rely on patent protection, as well as a combination of copyright, trade secret and trademark laws, and nondisclosure,
confidentiality and other contractual restrictions to protect our proprietary technology. However, these legal means afford only
limited protection and may not adequately protect our rights or permit us to gain or keep any competitive advantage. For
example, we cannot assure you that any of our pending patent applications will result in the issuance of patents to us. The U.S.
Patent and Trademark Office, or PTO, may deny or require significant narrowing of claims in our pending patent applications,
and patents issued as a result of the pending patent applications, if any, may not provide us with significant commercial
protection or be issued in a form that is advantageous to us. We could also incur substantial costs in proceedings before the
PTO. These proceedings could result in adverse decisions as to the priority of our inventions and the narrowing or invalidation
of claims in issued patents. Our issued patents and those that may be issued in the future could subsequently be successfully
challenged by others and invalidated or rendered unenforceable, which could limit our ability to stop competitors from
marketing and selling related products. In addition, our pending patent applications include claims to aspects of our products
and procedures that are not currently protected by issued patents.

Both the patent application process and the process of managing patent disputes can be time consuming and expensive.
Competitors may be able to design around our patents or develop products that provide outcomes that are comparable to our
products but fall outside of the scope of our patent protection. Although we have entered into confidentiality agreements and
intellectual property assignment agreements with certain of our employees, consultants and advisors as one of the ways we seek
to protect our intellectual property and other proprietary technology, such agreements may not be enforceable or may not
provide meaningful protection for our trade secrets or other proprietary information in the event of unauthorized use or
disclosure or other breaches of the agreements. Furthermore, the laws of some foreign countries may not protect our intellectual
property rights to the same extent as the laws of the U.S., if at all. Since most of our issued patents and pending patent
applications are for the U.S. only, we lack a corresponding scope of patent protection in other countries, including Japan. Thus,
we may not be able to stop a competitor from marketing products in other countries that are similar to some of our products.

In the event a competitor infringes upon one of our patents or other intellectual property rights, enforcing those patents

and rights may be difficult and time consuming. Even if successful, litigation to defend our patents against challenges or to
enforce our intellectual property rights could be expensive and time consuming and could divert management’s attention from
managing our business. Moreover, we may not have sufficient resources to defend our patents against challenges or to enforce
our intellectual property rights.

The medical device industry is characterized by patent and other intellectual property litigation and we could become subject
to litigation that could be costly, result in the diversion of management’s time and efforts, require us to pay damages, and/or
prevent us from marketing our existing or future products.

The medical device industry is characterized by extensive litigation and administrative proceedings over patent and other

intellectual property rights. Determining whether a product infringes a patent involves complex legal and factual issues, the
determination of which is often uncertain. Our competitors may assert that our products, the components of those products, the
methods of using those products, or the methods we employ in manufacturing or processing those products are covered by U.S.
or foreign patents held by them. In addition, they may claim that their patents have priority over ours because their patents were
filed first. Because patent applications can take many years to issue, there may be applications now pending of which we are
unaware, which may later result in issued patents that our products may infringe. There could also be existing patents that one
or more components of our products may be inadvertently infringing, of which we are unaware. As the number of participants
in the market for spine disorder devices and treatments increases, the possibility of patent infringement claims against us also
increases.

Any such claim against us, even those without merit, may cause us to incur substantial costs, and could place a significant

strain on our financial resources, divert the attention of management from our core business and harm our reputation. If the
relevant patents are upheld as valid and enforceable and we are found to infringe, we could be required to pay substantial
damages, including treble, or triple, damages if an infringement is found to be willful, and/or royalties and we could be
prevented from selling our products unless we could obtain a license or were able to redesign our products to avoid
infringement. Any such license may not be available on reasonable terms, if at all, and there can be no assurance that we would
be able to redesign our products in a way that would not infringe those patents, and any such redesign, if possible, may be
costly. If we fail to obtain any required licenses or make any necessary changes to our products or technologies, we may have
to withdraw existing products from the market or may be unable to commercialize one or more of our products, either of which
could have a significant adverse effect on our business, financial condition and results of operations.

In addition, in order to further our product development efforts, from time to time we enter into agreements with surgeons
to develop new products. As consideration for product development activities rendered pursuant to these agreements, in certain
instances we have agreed to pay such surgeons royalties on products developed by cooperative involvement between us and
such surgeons. There can be no assurance that surgeons with whom we have entered into such an arrangement will not claim to
be entitled to a royalty even if we do not believe that such products were developed by cooperative involvement between us
and such surgeons. Any such claim against us, even those without merit, may cause us to incur substantial costs, and could
place a significant strain on our financial resources, divert the attention of management from our core business and harm our
reputation.

If we become subject to product liability claims, we may be required to pay damages that exceed our insurance coverage.

Our business exposes us to potential product liability claims that are inherent in the testing, design, manufacture and sale

of medical devices for spine surgery procedures. Spine surgery involves significant risk of serious complications, including
bleeding, nerve injury, paralysis and even death. To date, our products have not been the subject of any material product
liability claims. Currently, we carry product liability insurance in the amount of $20 million per occurrence and $20 million in
the aggregate. Our existing product liability insurance coverage may be inadequate to satisfy liabilities we might incur. Any
product liability claim brought against us, with or without merit, could result in the increase of our product liability insurance
rates or our inability to secure coverage in the future on commercially reasonable terms, if at all. In addition, if our product
liability insurance proves to be inadequate to pay a damage award, we may have to pay the excess out of our cash reserves,
which could harm our financial condition. If longer-term patient results and experience indicate that our products or any
component of our products cause tissue damage, motor impairment or other adverse effects, we could be subject to significant
liability. Even a meritless or unsuccessful product liability claim could harm our reputation in the industry, lead to significant
legal fees and result in the diversion of management’s attention from managing our business. If a product liability claim or
series of claims is brought against us in excess of our insurance coverage limits, our business could suffer and our financial
condition, results of operations and cash flow could be materially adversely impacted.

Because biologics products entail a potential risk of communicable disease to human recipients, we may be the subject of
product liability claims regarding our biologics products.

Our biologics products may expose us to additional potential product liability claims. The development of biologics
products entails a risk of additional product liability claims because of the risk of transmitting disease to human recipients, and
substantial product liability claims may be asserted against us. In addition, successful product liability claims made against one
of our competitors could cause claims to be made against us or expose us to a perception that we are vulnerable to similar
claims. Even a meritless or unsuccessful product liability claim could harm our reputation in the industry, lead to significant
legal fees and result in the diversion of management’s attention from managing our business.

Any claims relating to our improper handling, storage or disposal of biological, hazardous and radioactive materials could
be time consuming and costly.

The manufacture of certain of our products, including our biologics products, involves the controlled use of biological,
hazardous and/or radioactive materials and waste. Our business and facilities and those of our suppliers are subject to foreign,
federal, state and local laws and regulations governing the use, manufacture, storage, handling and disposal of these hazardous
materials and waste products. Although we believe that our safety procedures for handling and disposing of these materials
comply with legally prescribed standards, we cannot completely eliminate the risk of accidental contamination or injury from
these materials. In the event of an accident, we could be held liable for damages or penalized with fines. This liability could
exceed our resources and any applicable insurance. In addition, under some environmental laws and regulations, we could also
be held responsible for all of the costs relating to any contamination at our past or present facilities and at third-party waste
disposal sites, even if such contamination was not caused by us. We may incur significant expenses in the future relating to any
failure to comply with environmental laws. Any such future expenses or liability could have a significant negative impact on
our business, financial condition and results of operations.

We may be subject to damages resulting from claims that we, our employees or our independent distributors have
wrongfully used or disclosed alleged trade secrets of our competitors or are in breach of non-competition or non-solicitation
agreements with our competitors.

Many of our employees were previously employed at other medical device companies, including our competitors or
potential competitors. Many of our independent distributors sell, or in the past have sold, products of our competitors. We
may be subject to claims that we, our employees or our independent distributors have inadvertently or otherwise used or
disclosed the trade secrets or other proprietary information of our competitors. In addition, we have been and may in the future
be subject to claims that we caused an employee or independent distributor to break the terms of his or her non-competition
agreement or non-solicitation agreement. Litigation may be necessary to defend against such claims. Even if we are successful
in defending against such claims, litigation could result in substantial costs and be a distraction to management. If we fail in
defending such claims, in addition to paying monetary damages, we may lose valuable intellectual property rights and/or
personnel. A loss of key personnel and/or their work product could hamper or prevent our ability to commercialize products,
which could have an adverse effect on our business, financial condition and results of operations.

We, certain of our directors and officers and HealthpointCapital have been named as a defendant in a litigation matter, the
result of which is uncertain.

On August 10, 2010, a purported securities class action complaint was filed in the United States District Court for the
Southern District of California on behalf of all persons who purchased our common stock between December 19, 2009 and
August 5, 2010 against us and certain of our directors and officers alleging violations of the Securities Exchange Act of 1934,
as amended, and Rule 10b-5 promulgated thereunder. On February 17, 2011, an amended complaint was filed against us and
certain of its directors and officers adding alleged violations of the Securities Act of 1933, as amended. HealthpointCapital,
Jefferies & Company, Inc., Canaccord Adams, Inc., Cowen and Company, Inc., and Lazard Capital Markets LLC are also
defendants in this action. The complaint alleges that the defendants made false or misleading statements, as well as failed to
disclose material facts, about our business, financial condition, operations and prospects, particularly relating to the Scient’x
transaction and our financial guidance following the closing of the acquisition. The complaint seeks unspecified monetary
damages, attorneys’ fees, and other unspecified relief. We believe that the claims are without merit and we intend to vigorously
defend ourselves against this complaint. However, the outcome of the litigation cannot be predicted at this time and any
outcome that is adverse to us, regardless of who the defendant is, could have a significant adverse effect on our financial
condition and results of operations. For a more detailed description of this matter, please see "Item 3 Legal Proceedings".

Risks Related to Our Common Stock

We expect that the price of our common stock will fluctuate substantially and the market price of our common stock may
decline in value in the future.

The market price of our common stock is likely to be highly volatile and may fluctuate substantially due to many factors,

including:

•

volume and timing of orders for our products;

quarterly variations in our or our competitors’ results of operations;

• our announcement or our competitors’ announcements regarding new products, product enhancements, significant

contracts, number of distributors, number of hospitals and surgeons using products, acquisitions, collaborative or strategic
investments;

• announcements of technological or medical innovations for the treatment of spine pathology;

• changes in earnings estimates or recommendations by securities analysts;

• our ability to develop, obtain regulatory clearance or approval for, and market new and enhanced products on a timely

basis;

• changes in healthcare policy in the U.S. and internationally;

• product liability claims or other litigation involving us;

• sales of large blocks of our common stock, including sales by our executive officers, directors and significant

stockholders;

• changes in governmental regulations or in the status of our regulatory approvals, clearances or applications;

• disputes or other developments with respect to intellectual property rights;

• changes in the availability of third-party reimbursement in the U.S. or other countries;

• changes in accounting principles; and

• general market conditions and other factors, including factors unrelated to our operating performance or the operating

performance of our competitors.

We may become involved in additional securities class action litigation that could divert management’s attention and harm
our business.

The stock market in general, The NASDAQ Global Select Market and the market for medical device companies in

particular, has experienced extreme price and volume fluctuations that have often been unrelated or disproportionate to the
operating performance of those companies. Further, the market prices of securities of medical device companies have been
particularly volatile. In the past, following periods of volatility in the market price of a particular company’s securities,
securities class action litigation has often been brought against that company. We may become involved in this type of litigation
in the future. Litigation is often expensive and diverts management’s attention and resources, which could materially harm our
financial condition, results of operations and business.

Securities analysts may not continue to provide coverage of our common stock or may issue negative reports, which
may have a negative impact on the market price of our common stock.

Securities analysts may not continue to provide research coverage of our common stock. If securities analysts do not

cover our common stock, the lack of research coverage may cause the market price of our common stock to decline. The
trading market for our common stock may be affected in part by the research and reports that industry or financial analysts
publish about our business. If one or more of the analysts who elects to cover us downgrades our stock, our stock price would
likely decline rapidly. If one or more of these analysts ceases coverage of us, we could lose visibility in the market, which in
turn could cause our stock price to decline. In addition, rules mandated by the Sarbanes-Oxley Act and a global settlement
reached in 2003 between the SEC, other regulatory agencies and a number of investment banks have led to a number of
fundamental changes in how analysts are reviewed and compensated. In particular, many investment banking firms are required
to contract with independent financial analysts for their stock research. It may be difficult for companies such as ours, with
smaller market capitalizations, to attract independent financial analysts that will cover our common stock. This could have a
negative effect on the market price of our stock.

Because of their significant stock ownership, our executive officers, directors and principal stockholders will be able to exert
control over us and our significant corporate decisions.

Based on shares outstanding at February 25, 2015, our executive officers, directors and stockholders holding more than

5% of our outstanding common stock and their affiliates, in the aggregate, beneficially own approximately 35% of our
outstanding common stock. As a result, these persons will have the ability to impact significantly the outcome of all matters
requiring stockholder approval, including the election and removal of directors and any merger, consolidation, or sale of all or
substantially all of our assets.

This concentration of ownership may harm the market price of our common stock by, among other things:

• delaying, deferring or preventing our change in control;

•

impeding a merger, consolidation, takeover or other business combination involving us;

• causing us to enter into transactions or agreements that are not in the best interests of all of our stockholders; or

•

reducing our public float held by non-affiliates.

Certain members of our Board of Directors also serve as officers and directors of HealthpointCapital, its affiliates and other
portfolio companies.

Four members of our Board of Directors also serve as officers and directors of our largest stockholder,

HealthpointCapital, or its related entities and of other companies in which HealthpointCapital invests, including companies
with which we compete or may in the future compete. As of February 25, 2015, HealthpointCapital owned approximately 32%
of our outstanding common stock. The Chairman of our Executive Committee of our Board of Directors, Mortimer Berkowitz
III, is a managing member of HGP, LLC and HGP II, LLC, the general partners of HealthpointCapital Partners, LP and
HealthpointCapital Partners II, LP, respectively. John H. Foster, a member of our Board of Directors, is a managing member of
HGP, LLC and HGP II, LLC and the Chairman, Chief Executive Officer, a member of the Board of Managers and a Managing
Director of HealthpointCapital, LLC. Our directors R. Ian Molson and Stephen E. O’Neil also serve on the board of managers
of HealthpointCapital, LLC. Each of Messrs. Berkowitz, Foster, O’Neil and Molson, also have financial interests in
HealthpointCapital investment funds. James Glynn has made a passive investment in HealthpointCapital investment funds. Mr.
Glynn does not have any decision-making authority with respect to how such amount is invested and managed by
HealthpointCapital.

Because of these possible conflicts of interest, such directors may direct potential business and investment opportunities
to other entities rather than to us or such directors may undertake or otherwise engage in activities or conduct on behalf of such
other entities that is not in, or which may be adverse to, our best interests. Whether a director directs an opportunity to us or to
another company, our directors may face claims of breaches of fiduciary duty and other duties relating to such opportunities.
Our amended and restated certificate of incorporation requires us to indemnify our directors to the fullest extent permitted by
law, which may require us to indemnify them against claims of breaches of such duties arising from their service on our Board
of Directors. HealthpointCapital or its affiliates may pursue acquisition opportunities that may be complementary to our
business and, as a result, those acquisition opportunities may not be available to us. Furthermore, HealthpointCapital may have
an interest in us pursuing acquisitions, divestitures, financings or other transactions that, in its judgment, could enhance its
equity investment, even though such transactions might involve risks to us and our stockholders generally. In addition, if we
were to seek a business combination with a target business with which one or more of our existing stockholders or directors
may be affiliated, conflicts of interest could arise in connection with negotiating the terms of and completing the business
combination. Conflicts that may arise may not be resolved in our favor.

Anti-takeover provisions in our organizational documents and change of control provisions in some of our employment
agreements and agreements with distributors, and in some of our outstanding debt agreements, as well as the terms of our
redeemable preferred stock, may discourage or prevent a change of control, even if an acquisition would be beneficial to our
stockholders, which could affect our stock price adversely.

Certain provisions of our amended and restated certificate of incorporation and restated by-laws could discourage, delay
or prevent a merger, acquisition or other change in control that stockholders may consider favorable, including transactions in
which our stockholders might otherwise receive a premium for their shares. These provisions also could limit the price that
investors might be willing to pay in the future for shares of our common stock, thereby depressing the market price of our
common stock. Stockholders who wish to participate in these transactions may not have the opportunity to do so. Furthermore,
these provisions could prevent or frustrate attempts by our stockholders to replace or remove our management. These
provisions:

• allow the authorized number of directors to be changed only by resolution of our Board of Directors;

• allow vacancies on our Board of Directors to be filled only by resolution of our Board of Directors;

• authorize our Board of Directors to issue, without stockholder approval, blank check preferred stock that, if issued, could
operate as a “poison pill” to dilute the stock ownership of a potential hostile acquirer to prevent an acquisition that is not
approved by our Board of Directors;

•

require that stockholder actions must be effected at a duly called stockholder meeting and prohibit stockholder action by
written consent;

• establish advance notice requirements for stockholder nominations to our Board of Directors and for stockholder

proposals that can be acted on at stockholder meetings; and

•

limit who may call stockholder meetings.

Some of our employment agreements and all of our restricted stock agreements and incentive stock option agreements
provide for accelerated vesting of benefits, including full vesting of restricted stock and options, upon a change of control. A
limited number of our agreements with our distributors include a provision that extends the term of the distribution agreement
upon a change in control and makes it more difficult for us or our successor to terminate the agreement. These provisions
may discourage or prevent a change of control.

In addition, in the event of a change of control, we would be required to redeem all outstanding shares of our redeemable

preferred stock for an aggregate of $29.9 million, at the price of $9.00 per share. Further, our amended and restated certificate
of incorporation permits us to issue additional shares of preferred stock. The terms of our redeemable preferred stock or any
new preferred stock we may issue could have the effect of delaying, deterring or preventing a change in control.

SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS

This Annual Report on Form 10-K and, in particular, the description of our "Business" set forth in Item 1, the "Risk
Factors" set forth in this Item 1A and our "Management’s Discussion and Analysis of Financial Condition and Results of
Operations" set forth in Item 7 contain or incorporate a number of forward-looking statements within the meaning of
Section 27A of the Securities Act of 1933, as amended, or the Securities Act, and Section 21E of the Securities Exchange Act of
1934, as amended, or the exchange Act, including statements regarding:

• our estimates regarding anticipated operating losses, future revenue, expenses, capital requirements, and liquidity,

including our anticipated revenue growth and cost savings;

• our ability to market, improve, grow, commercialize and achieve market acceptance of any of our products or any product

candidates that we are developing or may develop in the future;

• our beliefs about the enhance features, strengths and benefits of our products and product platform and our intention to

provide unmatched service to the surgeon community;

•

the effect of our strategy to streamline our organization and lower our costs;

• our ability to successfully integrate, and realize benefits from acquisitions;

• our ability to successfully achieve and maintain regulatory clearance or approval for our products in applicable

jurisdictions and in a timely manner;

•

the effect of any existing or future federal, state or international regulations on our ability to effectively conduct our
business;

• our business strategy and our underlying assumptions about market data, demographic trends, reimbursement trends and

pricing trends;

• our ability to achieve profitability, and the potential need to raise additional funding;

• our ability to maintain an adequate sales network for our products, including to attract and retain independent distributors;

• our ability to enhance our U.S. and international sales and distributions networks and product penetration;

• our ability to increase the use and promotion of our products by training and educating surgeons;

• our ability to attract and retain a qualified management team, as well as other qualified personnel and advisors;

• our ability to enter into licensing, collaboration and business combination agreements with third parties and to

successfully integrate the acquired technology and/or businesses;

• our management team’s ability to accommodate growth and manage a larger organization;

• our ability to protect our intellectual property, and to not infringe upon the intellectual property of third parties;

• our ability to maintain compliance with the requirements of the FDA and similar regulatory authorities outside of the

U.S.;

•

the effects of the escalating cost of medical products and services and the effects of market demand, government
regulation, third-party reimbursement policies and societal pressures on the worldwide healthcare industry and our
business;

•

our ability to meet the financial covenants under our credit facilities;

our ability to conclude that we have effective disclosure controls and procedures;

our ability to meet or exceed the industry standard in clinical and legal compliance and corporate governance programs;

our beliefs about our competitors and the principal competitive factors in our market and the effect of non-operatie
treatments on demand for our products;

potential liability resulting from litigation;

our beliefs about our employee relations;

potential liability resulting from a governmental review of our business practices;

potential liability from not meeting the payment obligations under either the Cross Medical or Orthotec settlements; and

other factors discussed elsewhere in this Annual Report on Form 10-K or any document incorporated by reference herein
or therein.

Any or all of our forward-looking statements in this Annual Report may turn out to be wrong. They can be affected by
inaccurate assumptions by known or unknown risks and uncertainties. Many factors mentioned in our discussion in this Annual
Report on Form 10-K will be important in determining future results. Consequently, no forward-looking statement can be
guaranteed. Actual future results may vary materially from expected results.

We also provide a cautionary discussion of risks and uncertainties under “Risk Factors” in Item 1A of this Annual Report.

These are factors that we think could cause our actual results to differ materially from expected results. Other factors besides
those listed there could also adversely affect us.

Without limiting the foregoing, the words “believe,” “anticipate,” “plan,” “expect,” “may,” “could,” “would,” “seek,”

“intend,” and similar expressions are intended to identify forward-looking statements. There are a number of factors and
uncertainties that could cause actual events or results to differ materially from those indicated by such forward-looking
statements, many of which are beyond our control, including the factors set forth under “Item 1A Risk Factors.” In addition, the
forward-looking statements contained herein represent our estimate only as of the date of this filing and should not be relied
upon as representing our estimate as of any subsequent date. While we may elect to update these forward-looking statements at
some point in the future, we specifically disclaim any obligation to do so to reflect actual results, changes in assumptions or
changes in other factors affecting such forward-looking statements.

Item 1B.

Unresolved Staff Comments

None.

Item 2.

Properties

Our corporate office and manufacturing facilities are located in Carlsbad, California. The table below provides selected

information regarding our current material operating leased locations.

Location
Carlsbad, California

Carlsbad, California

Use
Corporate headquarters and product design
Product design and manufacturing

Approximate
Square
Footage
76,693

Lease Expiration
January 2016

73,480

January 2017

Item 3.

Legal Proceedings

Litigation

On March 15, 2014, we, Orthotec, LLC and certain other parties, including certain directors and affiliates of us, entered

into a binding term sheet, or the Binding Term Sheet, to resolve the Orthotec, LLC v. Surgiview, S.A.S, et al. matter in the
Superior Court of California, Los Angeles County and related litigation matters, or the Orthotec Settlement. Pursuant to the
terms contained in the Binding Term Sheet, we agreed to pay Orthotec, LLC $49 million in cash, including initial cash
payments totaling $1.75 million, which the Company previously paid in March 2014, and an additional lump sum payment of
$15.75 million, which the Company previously paid in June 2014. The Company agreed to pay the remaining $31.5 million in
28 quarterly installments of $1.1 million and then one additional quarterly installment of $700,000, commencing October 1,
2014. We have the right to prepay the amounts due without penalty. In addition, the unpaid balance of the amounts due will
accrue interest at the rate of 7% per year beginning May 15, 2014 until the amounts due are paid in full. The accrued but unpaid
interest will be paid in quarterly installments of $1.1 million (or the full amount of the accrued but unpaid interest if less than
$1.1 million) following the full payment of the $31.5 million in quarterly installments described above. No interest will accrue
on the accrued interest. The Binding Term Sheet provided for mutual releases of all claims in the Orthotec, LLC v. Surgiview,
S.A.S, et al. matter in the Superior Court of California, Los Angeles County and all other related litigation matters involving us
and our directors and affiliates.

On September 26, 2014, we entered into a Settlement and Release Agreement, dated as of August 13, 2014, by and
among us and our direct and indirect subsidiaries and affiliates, including Alphatec Spine, Inc. and its direct and indirect
subsidiaries, Alphatec Holdings International C.V. and its direct and indirect subsidiaries and affiliates, including Scient'x
S.A.S. and Surgiview S.A.S.; HealthpointCapital, LLC, HealthpointCapital Partners, L.P., HealthpointCapital Partners II, L.P.,
John H. Foster and Mortimer Berkowitz III; and Orthotec, LLC and Patrick Bertranou, or the Settlement Agreement. The
Settlement Agreement contains substantially the same business terms as the Binding Term Sheet set forth above, and
supersedes the Binding Term Sheet.

On August 10, 2010, a purported securities class action complaint was filed in the United States District Court for the
Southern District of California on behalf of all persons who purchased our common stock between December 19, 2009 and
August 5, 2010 against us and certain of our directors and officers alleging violations of the Exchange Act and Rule 10b-5
promulgated thereunder. On February 17, 2011, an amended complaint was filed against us and certain of our directors and
officers adding alleged violations of the Securities Act. HealthpointCapital, Jefferies & Company, Inc., Canaccord Adams, Inc.,
Cowen and Company, Inc., and Lazard Capital Markets LLC are also defendants in this action. The complaint alleges that the
defendants made false or misleading statements and failed to disclose material facts about our business, financial condition,
operations and prospects, particularly relating to the Scient’x transaction and our financial guidance following the closing of
the acquisition. The complaint seeks unspecified monetary damages, attorneys’ fees, and other unspecified relief. We filed a
motion to dismiss the amended complaint on April 18, 2011. The district court granted the motion to dismiss with leave to
amend on March 22, 2012. On April 19, 2012, the lead plaintiff filed a Second Amended Complaint alleging violations of
Sections 10(b) and 20(a) of the Exchange Act and violations of Section 11, 12(a)(2), and 15 of the Securities Act against the
same named defendants. On May 3, 2012, we filed a motion to dismiss the Second Amended Complaint. The district court
granted that motion without leave to amend and entered final judgment in our favor on March 28, 2013. On April 17, 2013, the
lead plaintiff filed a notice of appeal to the United States Court of Appeals for the Ninth Circuit. The appeal has been fully
briefed. We believe that the claims are without merit and we intend to vigorously defend ourselves against this complaint.
However, the outcome of the litigation cannot be predicted at this time and any outcome that is adverse to us, regardless of who
the defendant is, could have a significant adverse effect on our financial condition and results of operations.

On August 25, 2010, an alleged shareholder of ours filed a derivative lawsuit in the Superior Court of California, San

Diego County, purporting to assert claims on behalf of us against all of our directors and certain of our officers and
HealthpointCapital. Following the filing of this complaint, similar complaints were filed in the same court and in the U.S.
District Court for the Southern District of California against the same defendants containing similar allegations. The complaint
filed in federal court was dismissed by the plaintiff without prejudice in July 2011. The state court complaints were
consolidated into a single action and we were named as a nominal defendant in the consolidated action. Each complaint alleges
that our directors and certain of our officers breached their fiduciary duties to us related to the Scient’x transaction, and by
making allegedly false statements that led to unjust enrichment of HealthpointCapital and certain of our directors. The
complaints seek unspecified monetary damages and an order directing us to adopt certain measures purportedly designed to
improve our corporate governance and internal procedures. On January 8, 2014, the parties reached an agreement in principle
to resolve all claims in exchange for corporate governance reforms and payment of attorneys’ fees in the amount of $5.25
million, to be paid by our and HeathpointCapital’s respective insurance carriers. The final settlement was approved by the
Court in August 2014.

At December 31, 2014, the probable outcome of any of the aforementioned litigation matters that have not reached a
settlement cannot be determined nor can we estimate a range of potential loss. Accordingly, in accordance with the authoritative
guidance on the evaluation of contingencies, we have not recorded an accrual related to any litigation matters that have not
reached a settlement. We are and may become involved in various other legal proceedings arising from our business activities.
While management does not believe the ultimate disposition of the above matters that have not yet been settled will have a
material adverse impact on our consolidated results of operations, cash flows or financial position, litigation is inherently
unpredictable, and depending on the nature and timing of these proceedings, an unfavorable resolution could materially affect
our future consolidated results of operations, cash flows or financial position in a particular period.

Item 4.

Mine Safety Disclosures

Not applicable.

PART II

Item 5.

Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity
Securities

Market Information

Our common stock is traded on The NASDAQ Global Select Market under the symbol “ATEC.” The following table sets

forth the high and low sales prices for our common stock as reported on The NASDAQ Global Select Market for the periods
indicated.

Year Ended December 31, 2014
First quarter
Second quarter
Third quarter
Fourth quarter
Year Ended December 31, 2013
First quarter
Second quarter
Third quarter
Fourth quarter

Stockholders

High

Low

High

2.53
1.70
1.92
1.70

2.40
2.10
2.41
2.15

Low

1.16
1.20
1.32
1.23

1.55
1.71
1.92
1.75

As of February 25, 2015, there were approximately 389 holders of record of an aggregate 99,848,142 shares of our

common stock.

Dividend Policy

We have never declared or paid cash dividends on our capital stock. We currently intend to retain all available funds and
any future earnings for use in the operation and expansion of our business and do not anticipate paying any cash dividends in
the foreseeable future.

Sales of Unregistered Securities

In October 2013, we entered into a three-year collaboration agreement with a third party to provide consultation services
to assist us in the development of our products and products in development. Under the terms of the collaboration agreement,
we will gain exclusive rights to the use of all intellectual property developed by the collaborators. We will make three annual
payments to the collaborator as sole consideration for services provided, totaling an aggregate of up to $8 million, paid in our
common stock at a per share price of $1.95, which was equal to the average NASDAQ closing price of the common stock on
the five days leading up to and including the date of signing the collaboration agreement. The actual number of shares issued
each year will be determined by the fair market value of the services provided over the prior 12 months. On October 30, 2013,
November 10, 2014 and December 24, 2014, we issued 128,571, 1,059,792 and 267,672, respectively, unregistered shares of
our common stock under this agreement. The shares were issued in reliance upon an exemption from registration under federal
securities laws provided by Section 4(2) of the Securities Act, for the issuance and exchange of securities in transactions by an
issuer not involving a public offering. We do not have an obligation, nor does it anticipate, registering the issued shares for
resale on a registration statement pursuant to the Securities Act.

Issuer Purchases of Equity Securities

Under the terms of our Amended and Restated 2005 Employee, Director and Consultant Stock Plan, as amended, or the

Stock Plan, we may award shares of restricted stock to our employees, directors and consultants. These shares of restricted
stock are subject to a lapsing right of repurchase by us. We may exercise this right of repurchase in the event that a restricted
stock recipient’s employment, directorship or consulting relationship with us terminates prior to the end of the vesting period. If
we exercise this right, we are required to repay the purchase price paid by or on behalf of the recipient for the repurchased
restricted shares. Repurchased shares are returned to the Stock Plan and are available for future awards under the terms of the
Stock Plan. Common shares repurchased during the quarter ended December 31, 2014 were as follows:

Period
October 2014
November 2014
December 2014

Total Number
of Shares
Purchased (1)

Average Price
Paid per
Share

Total Number of
Shares Purchased
as part of Publicly
Announced Plans
or Programs

Maximum Number
of Shares That May
Yet Be Purchased
Under the Plans or
Programs

— $
— $
— $

—
—
—

(1) Not included in the table above are 9,388 shares of common stock forfeited and retired in connection with the payment

of minimum statutory withholding taxes due upon the vesting of certain stock awards or the exercise of certain stock
options. In lieu of making a cash payment with respect to such withholding taxes, the holders of such stock forfeited a
number of shares at the then current fair market value of the shares to pay such taxes.

Item 6.

Selected Financial Data

The following table sets forth consolidated financial data with respect to the Company for each of the five years in the

period ended December 31, 2014. The selected consolidated financial data set forth below have been derived from our audited
consolidated financial statements, and may not be indicative of future operating results. The results of operations for the year
ended December 31, 2013 include litigation settlement expenses of $46.0 million and restructuring expenses of $9.7 million.
The results of operations for the year ended December 31, 2010 do not include the results of Scient’x for the first quarter 2010
as the acquisition of Scient'x closed on March 26, 2010. The selected consolidated financial data set forth below should be read
in conjunction with our audited consolidated financial statements and related notes thereto found at “Item 8 Financial
Statements and Supplementary Data” and “Item 7 Management’s Discussion and Analysis of Financial Condition and Results
of Operations” included elsewhere in this Annual Report on Form 10-K.

Year Ended December 31,

2014

2013

2012

2011

2010

(in thousands, except per share amounts)

Consolidated Statement of Operations Data:
Revenues

Operating income (loss)

Loss from continuing operations

Income from discontinued operations

Net loss

$ 206,980

$ 171,610
(11,789)
(14,433)
78
$ (12,882) $ (82,227) $ (15,459) $ (22,181) $ (14,355)

$ 197,711
(24,516)
(22,181)
—

$ 204,724
(73,433)
(82,227)
—

$ 196,278
(9,837)
(15,459)
—

1,844
(12,882)
—

Net loss per basic share

Net loss per diluted share

(0.13) $
(0.16) $

(0.85) $
(0.85) $

(0.17) $
(0.17) $

(0.25) $
(0.25) $

(0.18)
(0.18)

Weighted-average shares used in computing net loss per share:

Shares used in calculating basic net loss per share

Shares used in calculating diluted net loss per share

97,347

97,735

96,235

90,218

88,798

78,590

Consolidated Balance Sheet Data:
Cash

Working capital
Total assets

Long-term debt, less current portion

Redeemable preferred stock

Total stockholders’ equity

As of December 31,

2014

2013

2012

2011

2010

(in thousands)

$ 19,735

$ 21,345

$ 22,241

$ 20,666

$ 23,168

49,511
344,923

74,597

23,603

34,026
365,630

49,978

23,603

65,264
382,127

39,967

23,603

59,292
366,692

23,802

23,603

79,233
377,016

32,474

23,603

148,954

171,676

245,816

245,328

266,434

Item 7.

Management’s Discussion and Analysis of Financial Condition and Results of Operations

The following discussion of our financial condition and results of operations should be read in conjunction with the

financial statements and the notes to those statements appearing elsewhere in this Annual Report on Form 10-K. Some of the
information contained in this discussion and analysis or set forth elsewhere in this report include the identification of certain
trends and other statements that may predict or anticipate future business or financial results that are subject to important
factors that could cause our actual results to differ materially from those indicated. See “Item 1A Risk Factors” included
elsewhere in this Annual Report on Form 10-K.

Overview

We are a medical technology company focused on the design, development, manufacturing and marketing of products for

the surgical treatment of spine disorders. We have a comprehensive product portfolio and pipeline that addresses the cervical,
thoracolumbar and intervertebral regions of the spine and covers a variety of major spinal disorders and surgical procedures.
Our principal product offerings are focused on the global market for orthopedic spinal disorder solutions. Our “physician-
inspired culture” enables us to respond to changing surgeon needs through collaboration with spinal surgeons to conceptualize,
design and co-develop a broad range of products. We have a state-of-the-art, in-house manufacturing facility that provides us
with a unique competitive advantage, and enables us to rapidly deliver solutions to meet surgeons’ and patients’ critical needs.
We believe that our products and systems have enhanced features and benefits that make them attractive to surgeons and that
our broad portfolio of products and systems provide a comprehensive solution for the safe and successful surgical treatment of
spinal disorders.

Revenue and Expense Components

The following is a description of the primary components of our revenues and expenses:

Revenues. We derive our revenues primarily from the sale of spinal surgery implants used in the treatment of spine

disorders. Spinal implant products include spine screws and complementary products, interbody devices, plates, and tissue-
based materials. Our revenues are generated by our direct sales force and independent distributors. Our products are requested
directly by surgeons and shipped and billed to hospitals and surgical centers. Today we have existing subsidiaries and/or
affiliates in Japan, Germany, Brazil, Italy and the U.K. through which we sell our products and independent distributors in over
50 countries throughout the world. A majority of our business is conducted with customers within markets in which we have
experience and with payment terms that are customary to our business. We may elect to defer revenues until the time of
collection if circumstances related to payment terms, regional market risk or customer history indicate that collectability is not
reasonably assured.

Cost of revenues. Cost of revenues consists of direct product costs, royalties, milestones, depreciation of our surgical

instruments, and the amortization of purchased intangibles. We manufacture substantially all of the non-tissue-based implants
that we sell. Our product costs consist primarily of direct labor, manufacturing overhead, and raw materials and components.
The product costs of certain of our biologics products include the cost of procuring and processing human tissue. We incur
royalties related to the technologies that we license from others and the products that are developed in part by surgeons with
whom we collaborate in the product development process. Amortization of purchased intangibles consists of amortization of
developed product technology.

Research and development. Research and development expense consists of costs associated with the design,

development, testing, and enhancement of our products. Research and development expense also includes salaries and related
employee benefits, research-related overhead expenses, fees paid to external service providers, and costs associated with our
Scientific Advisory Board and Executive Surgeon Panels.

In-process research and development, or IPR&D. In-process research and development expense consists of acquired
research and development assets that were not part of an acquisition of a business and were not technically feasible on the date
we acquired such technology, provided that such technology also did not have any alternative future use at that date.

Sales and marketing. Sales and marketing expense consists primarily of salaries and related employee benefits, sales

commissions and support costs, professional service fees, travel, medical education, trade show and marketing costs.

General and administrative. General and administrative expense consists primarily of salaries and related employee

benefits, professional service fees, insurance and legal expenses.

Transaction related expenses. Transaction related expenses consist of legal, accounting and financial advisory fees

associated with acquisitions.

Restructuring expenses. Restructuring expenses consist of severance, social plan benefits and related taxes, facility
closing costs, manufacturing transfer costs and contract termination incurred in connection with the reorganization of the
Scient’x operations in France.

Litigation settlement expenses. Litigation settlement expenses consist of significant settlements of lawsuits.

Total other income (expense). Total other income (expense) includes interest income, interest expense, changes in the fair

value of the warrant liabilities, gains and losses from foreign currency exchanges and other non-operating gains and losses.

Income tax provision (benefit). Income tax provision (benefit) consists primarily of income tax provision related to state
income taxes, foreign operations and uncertain tax positions in foreign jurisdictions, and the tax effect of changes in deferred
tax liabilities associated with tax deductible goodwill.

Results of Operations

The first table below sets forth our statements of operations data for the periods presented. Our historical results are not

necessarily indicative of the operating results that may be expected in the future.

Revenues
Cost of revenues
Amortization of acquired intangible assets
Gross profit
Operating expenses:

Research and development
In-process research and development
Sales and marketing
General and administrative
Amortization of acquired intangible assets
Transaction related expenses
Restructuring expenses
Litigation settlement expenses
Total operating expenses

Operating income (loss)
Other income (expense):
Interest income
Interest expense
Other income (expense), net

Total other income (expense)
Pretax net loss
Income tax provision (benefit)
Net loss

2014

Year Ended December 31,
2013

2012

206,980
61,834
1,736
143,410

16,799
527
77,179
43,381
2,974
—
706
—
141,566
1,844

(in thousands)

204,724
78,669
1,733
124,322

14,190
—
76,960
47,949
3,009
—
9,665
45,982
197,755
(73,433)

10
(13,616)
(33)
(13,639)
(11,795)
1,087
(12,882) $

6
(3,959)
(1,662)
(5,615)
(79,048)
3,179
(82,227) $

196,278
70,761
1,749
123,768

14,886
341
75,177
39,939
2,180
1,082
—
—
133,605
(9,837)

118
(6,105)
(794)
(6,781)
(16,618)
(1,159)
(15,459)

Year Ended December 31, 2014 Compared to the Year Ended December 31, 2013

Revenues. Revenues were $207.0 million for the year ended December 31, 2014 compared to $204.7 million for the year
ended December 31, 2013, representing an increase of $2.3 million, or 1.1%. The increase was the result of growth in both the
U.S. region ($2.1 million) and the International region ($0.1 million).

U.S. revenues were $137.1 million for the year ended December 31, 2014 compared to $135.0 million for the year ended

December 31, 2013, representing an increase of $2.1 million, or 1.6%. The increase was the result of increased sales direct to
hospitals ($5.2 million), offset by a decrease in sales to stocking distributors ($3.1 million).

International revenues were $69.9 million for the year ended December 31, 2014 compared to $69.8 million for the year

ended December 31, 2013, representing an increase of $0.1 million, or 0.2%. The increase was due to growth in sales of
implants and instruments ($5.5 million), offset by the elimination of revenue as a result of ceasing commercial operations in
France as a result of the restructuring ($5.4 million). The increase in revenue is inclusive of $2.9 million in unfavorable
exchange rate effect.

Cost of revenues. Cost of revenues was $61.8 million for the year ended December 31, 2014 compared to $78.7 million
for the year ended December 31, 2013, representing a decrease of $16.8 million, or 21.4%. The decrease was partially due to
the one-time charges in 2013 for increased inventory and instrument reserves related to the restructuring of the Scient'x
organization ($5.5 million), the obsolescence of the PureGen inventory ($3.5 million) and the obsolescence of certain inventory
related to an interbody fusion product ($1.0 million). In addition, there was a reduction in amortization expense related to the
Cross Medical settlement, for which expenses concluded in 2013 ($3.8 million), a reduction in depreciation expense related to
instruments ($2.2 million), and a decrease in inventory adjustments ($1.7 million), offset by an increase in product costs due to
the growth in sales ($0.3 million) and an increase in inventory reserves ($0.6 million).

Amortization of acquired intangible assets. Amortization of acquired intangible assets was $1.7 million for the years
ended December 31, 2014 and December 31, 2013. This expense represents amortization in the period for intangible assets
associated with product related assets obtained in acquisitions.

Gross profit. Gross profit was $143.4 million for the year ended December 31, 2014 compared to $124.3 million for the

year ended December 31, 2013, representing an increase of $19.1 million, or 15.4%. The increase was due to a reduction in the
cost of revenues ($17.3 million) and an increase in sales volume ($1.8 million).

Gross margin. Gross margin was 69.3% for the year ended December 31, 2014 compared to 60.7% for the year ended
December 31, 2013. The increase of 8.6 percentage points was due to a reduction in non-recurring charges and benefits (5.0
percentage points), amortization expense related to the Cross Medical settlement, for which expenses concluded in 2013 (2.0
percentage points), a reduction in depreciation expense related to instruments (1.1 percentage points) and reduction in
inventory adjustments (0.8 percentage points), offset by an increase in inventory reserves (0.3 percentage points).

Gross margin in the U.S. was 73.4% for the year ended December 31, 2014 compared to 65.9% for the year ended
December 31, 2013. The increase of 7.5 percentage points was due to a reduction in non-recurring charges and benefits (3.4
percentage points), amortization expense related to the Cross Medical settlement, for which expenses concluded in 2013 (3.1
percentage points), a reduction in depreciation expense related to instruments (1.0 percentage points), and a decrease in
inventory adjustments (0.7 percentage points), offset by an increase in inventory reserves (0.4 percentage points) and an
increase in royalty and milestone expenses due to a change in product mix (0.3 percentage points).

Gross margin for the International region was 61.3% for the year ended December 31, 2014 compared to 50.8% for the

year ended December 31, 2013. The increase of 10.5 percentage points was due to 2013 reserves related to the restructuring of
the Scient'x organization (7.9 percentage points), a reduction in instrument depreciation (1.3 percentage points) and a reduction
in inventory adjustments (1.5 percentage points), offset by an unfavorable variation in pricing and product mix (0.2 percentage
points).

Research and development. Research and development expense was $16.8 million for the year ended December 31, 2014

compared to $14.2 million for the year ended December 31, 2013 representing an increase of $2.6 million, or 18.4%. The
increase was primarily related to the beta launch of the Arsenal pedicle screw system and increased development activity.

In-process research and development. IPR&D expense was $0.5 million for the year ended December 31, 2014 compared

to $0 for the year ended December 31, 2013. The $0.5 million expense in 2014 relates to initial purchase payments in
connection with asset purchase agreements for which the underlying product was not technologically feasible at the time the
asset was acquired.

Sales and marketing. Sales and marketing expense was $77.2 million for the year ended December 31, 2014 compared to
$77.0 million for the year ended December 31, 2013 representing an increase of $0.2 million, or 0.3%. The increase was due to
an increase in commission expense ($2.1 million), offset by a reduction in the International region resulting from the
restructuring of the Scient'x organization ($1.9 million).

General and administrative. General and administrative expense was $43.4 million for the year ended December 31,

2014 compared to $47.9 million for the year ended December 31, 2013, representing a decrease of $4.6 million, or 9.5%. The
decrease was primarily due to a lower amount of legal expenses associated with the Orthotec litigation incurred in 2014 than
2013.

Amortization of acquired intangible assets. Amortization of acquired intangible assets was $3.0 million for the year ended
December 31, 2014 and compared to $3.0 million for the year ended December 31, 2013. This expense represents amortization
in the period for intangible assets associated with general business assets obtained in acquisitions.

Restructuring expenses. Restructuring expenses were $0.7 million for the year ended December 31, 2014 compared to
$9.7 million for the year ended December 31, 2013. On September 16, 2013, we announced that Scient'x began a process to
significantly restructure its business operations in France in an effort to improve operating efficiencies and rationalize its cost
structure. The restructuring included a reduction in Scient'x's workforce and closing of the manufacturing facilities in France.
The Company has recorded total costs of $10.4 million through December 31, 2014 associated with this restructuring, which
includes employee severance, social plan benefits and related taxes, facility closing costs, manufacturing transfer costs, and
contract termination costs. We have substantially completed the activities associated with the restructuring activities as of
December 31, 2014, and a substantial portion of the restructuring costs related to this restructuring has been paid.

Litigation settlement expenses. Litigation settlement expenses were $0 for the year ended December 31, 2014 compared

to $46.0 million for the year ended December 31, 2013. The 2013 amount relates to an accrual booked for litigation settlement
in connection with the Orthotec litigation matter described in Part 1, Item 3 Legal Proceedings.

Interest expense. Interest expense was $13.6 million for the year ended December 31, 2014 compared to $4.0 million for

the year ended December 31, 2013, representing an increase of $9.7 million, or 243.9%. Interest expense for the years ended
December 31, 2014 and 2013 consisted primarily of interest related to loan agreements and lines of credit and the associated
amortization expenses related to debt issuance costs. The increase in interest expense in 2014 is primarily due to interest
expense and amortization of debt discount related to the Deerfield facility ($6.2 million), imputed interest on the Orthotec
settlement ($1.7 million) and interest on higher levels of borrowings under the MidCap facility ($1.7 million).

Other income (expense), net. Other income (expense) was an expense of less than $0.1 million for the year ended
December 31, 2014 compared to an expense of $1.7 million for the year ended December 31, 2013, representing a decrease in
this expense of $1.6 million. The decrease in expense was primarily due to a gain from the decrease in the fair market value of
certain warrants ($2.6 million), partially offset by an increase in unfavorable foreign currency exchange results due to U.S.
denominated assets and liabilities on our foreign subsidiaries books and foreign currency losses ($1.0 million).

Income tax provision (benefit). Income tax provision (benefit) was a provision of $1.1 million for the year ended
December 31, 2014 compared to a provision of $3.2 million for the year ended December 31, 2013, representing a decrease of
$2.1 million, or 65.8%. The income tax provision in 2014 and 2013 consists primarily of income tax provisions related to state
income taxes, the tax effect of changes in deferred tax liabilities associated with tax deductible goodwill and operations in
foreign jurisdictions where we operate.

Year Ended December 31, 2013 Compared to the Year Ended December 31, 2012

Revenues. Revenues were $204.7 million for the year ended December 31, 2013 compared to $196.3 million for the year

ended December 31, 2012, representing an increase of $8.4 million, or 4.3%. The increase was comprised of $4.4 million
related to sales in the U.S. and $4.0 million related to International sales.

U.S. revenues were $135.0 million for the year ended December 31, 2013 compared to $130.5 million for the year ended
December 31, 2012, representing an increase of $4.5 million, or 3.4%. The increase was due to growth in the sales of implants
and instruments ($8.2 million) and Biologics ($2.1 million), offset by a decline in the sales of PureGen due to the voluntary
removal of PureGen from the market ($5.8 million).

International revenues were $69.8 million for the year ended December 31, 2013 compared to $65.8 million for the year

ended December 31, 2012, representing an increase of $4.0 million, or 6.0%. The increase was due to sales of Alphatec
implants and instruments internationally ($6.5 million), offset by a reduction in the sales of Scient'x products internationally
($2.5 million). The increase in revenue is inclusive of $5.9 million in unfavorable exchange rate effect.

Cost of revenues. Cost of revenues was $78.7 million for the year ended December 31, 2013 compared to $70.8 million
for the year ended December 31, 2012, representing an increase of $7.9 million, or 11.2%. The increase was primarily due to
one-time charges for increased inventory and instrument reserves related to the restructuring of the Scient'x organization ($5.5
million), the obsolescence of the PureGen inventory ($3.5 million) and the obsolescence of certain inventory related to an
interbody fusion product ($1.0 million). In addition to these charges, there is an increase related to higher product costs as a
result of sales volume and variation in product mix ($2.1 million), offset by an adjustment to milestone accruals ($0.7 million),
a reduction in inventory reserves ($2.9 million) and a reduction in inventory adjustments and other costs of sales ($0.4 million).

Amortization of acquired intangible assets. Amortization of acquired intangible assets was $1.7 million for the years
ended December 31, 2013 and December 31, 2012. This expense represents amortization in the period for intangible assets
associated with product related assets obtained in acquisitions.

Gross profit. Gross profit was $124.3 million for the year ended December 31, 2013 compared to $123.8 million for the
year ended December 31, 2012, representing an increase of $0.6 million, or 0.4%. The increase was due to an increase in sales
volume ($6.8 million), a reduction in inventory reserves ($2.9 million), a reversal of milestone accruals ($0.7 million) and a
decrease in other cost of revenues ($0.6 million), offset by an increase in the cost of revenues resulting from the restructuring
($5.5 million), product obsolescence ($4.5 million) and an unfavorable variation in product mix ($0.4 million).

Gross margin. Gross margin was 60.7% for the year ended December 31, 2013 compared to 63.1% for the year ended
December 31, 2012. The decrease of 2.4 percentage points was due to an increase in the cost of revenues resulting from the
French restructuring (2.6 percentage points), product obsolescence (2.2 percentage points) and an unfavorable variation in
pricing and product mix (0.2 percentage points), offset by a reduction in inventory reserves (1.6 percentage points), an
adjustment to milestone accruals (0.3 percentage points) and a reduction in other cost of revenues (0.7 percentage points).

Gross margin in the U.S. was 66.1% for the year ended December 31, 2013 compared to 67.7% for the year ended
December 31, 2012. The decrease of 1.6 percentage points was due to an increase in the cost of revenues resulting from product
obsolescence (3.2 percentage points) and an unfavorable variation in pricing and product mix (0.5 percentage points), offset by
a reduction in inventory adjustments (1.1 percentage points) and reduction in other cost of revenues (1.0 percentage points).

Gross margin for the International region was 50.3% for the year ended December 31, 2013 compared to 53.8% for the
year ended December 31, 2012. The decrease of 3.5 percentage points was due to an increase in the cost of revenues resulting
from the restructuring (7.9 percentage points), offset by a favorable variation in pricing and product mix (0.6 percentage points)
and a reduction in inventory reserves (3.8 percentage points).

Research and development. Research and development expense was $14.2 million for the year ended December 31, 2013

compared to $14.9 million for the year ended December 31, 2012, representing a decrease of $0.7 million, or 4.7%. The
decrease was primarily related to the variations in the timing of the cycle for development and testing ($1.4 million), offset by
increased surgeon consulting expenses ($0.7 million).

In-process research and development. IPR&D expense was $0 for the year ended December 31, 2013 compared to $0.3

million for the year ended December 31, 2012. During the fourth quarter of 2012, we decided to not pursue development of
IPR&D assets that had an indefinite life. We expensed $0.3 million for IPR&D related to the write-off of a portion of the
IPR&D assets acquired in the Scient’x acquisition.

Sales and marketing. Sales and marketing expense was $77.0 million for the year ended December 31, 2013 compared to

$75.2 million for the year ended December 31, 2012 representing an increase of $1.8 million, or 2.4%. The increase was
primarily due to the additional expense created by the recently enacted medical device excise tax ($1.5 million).

General and administrative. General and administrative expense was $47.9 million for the year ended December 31,
2013 compared to $39.9 million for the year ended December 31, 2012, representing an increase of $8.0 million, or 20.1%. The
increase was primarily related to legal fees associated with litigation ($5.4 million), compensation expense ($2.1 million),
professional fees ($1.3 million) and expenses resulting from the Phygen acquisition ($0.4 million), offset by a decrease in
International expenses related to currency translation ($0.8 million) and general cost reduction ($0.4 million).

Amortization of acquired intangible assets. Amortization of acquired intangible assets was $3.0 million for the year ended

December 31, 2013 compared to $2.2 million for the year ended December 31, 2012, representing an increase of $0.8 million,
or 38.0%. This expense represents amortization in the period for intangible assets associated with general business assets
obtained in acquisitions.

Transaction related expenses. Transaction related expenses were $0 for the year ended December 31, 2013 compared to

$1.1 million for the year ended December 31, 2012. The transaction related expenses were due to legal and professional fees in
connection with the Company’s acquisition of certain assets of Phygen, LLC in 2012.

Restructuring expenses. Restructuring expenses were $9.7 million for the year ended December 31, 2013 compared to $0

for the year ended December 31, 2012. On September 16, 2013, we announced that we had begun a process to significantly
restructure our Scient'x business operations in France in an effort to improve operating efficiencies and rationalize our cost
structure. The restructuring included a reduction in Scient'x's workforce and the closing of our manufacturing facilities in
France. We recorded restructuring costs of $9.7 million for the year ended December 31, 2013 and there was no corresponding
expense for the year ended December 31, 2012. We estimate that we will record total costs, including employee severance,
social plan benefits and related taxes, facility closing costs, manufacturing transfer costs and contract termination costs of
approximately $12 million associated with this restructuring. We expect to complete all the activities associated with the
restructuring activities by the end of the second quarter of 2014, a substantial portion of which will be paid by then.

Litigation settlement expenses. Litigation settlement expenses were $46.0 million for the year ended December 31, 2013.

The 2013 amount relates to an accrual booked for litigation settlement in connection with the Orthotec, litigation matter
described in Part 1 Item 3 Legal Proceedings.

Interest income. Interest income was $0 for the year ended December 31, 2013 compared to $0.1 million for the year

ended December 31, 2012. Interest income is earned on cash balances held in accounts invested in money market funds.

Interest expense. Interest expense was $4.0 million for the year ended December 31, 2013 compared to $6.1 million for

the year ended December 31, 2012, representing a decrease of $2.1 million, or 35.2%. Interest expense for the year ended
December 31, 2013 consisted primarily of interest related to loan agreements and lines of credit and the associated amortization
expenses related to debt issuance costs. Interest expense for the year ended December 31, 2012 included a loss on
extinguishment of debt costs of $2.9 million related to the refinancing of the term note and revolving credit facility with Silicon
Valley Bank, which consisted of $2.3 million of early termination fees and $0.6 million for the write-off of capitalized deferred
debt offering costs.

Other income (expense), net. Other income (expense) was an expense of $1.7 million for the year ended December 31,
2013 compared to an expense of $0.8 million for the year ended December 31, 2012, representing an increase in expense of
$0.9 million. The increase in expense was primarily due to unfavorable foreign currency exchange results realized in 2013 due
to having U.S. denominated assets and liabilities on our foreign subsidiaries books as compared to 2012.

Income tax provision (benefit). Income tax provision (benefit) was a provision of $3.2 million for the year ended
December 31, 2013 compared to a benefit of $1.2 million for the year ended December 31, 2012, representing an increase of
$4.3 million, or 374.3%. The income tax provision in 2013 consisted primarily of income tax provisions related to state income
taxes, the tax effect of changes in deferred tax liabilities associated with tax deductible goodwill and operations in foreign
jurisdictions where we operate. The income tax benefit in 2012 consisted primarily of tax benefits related to operations in
France and a settlement with the French tax authorities, partially offset by a valuation allowance on the French deferred tax
assets, income tax expense for various other foreign jurisdictions, state income taxes and the tax effect of changes in deferred
tax liabilities associated with tax deductible goodwill.

Non-GAAP Financial Measures

We utilize certain financial measures that are not calculated based on U.S. Generally Accepted Accounting Principles, or

GAAP. Certain of these financial measures are considered “non-GAAP” financial measures within the meaning of Item 10 of
Regulation S-K promulgated by the SEC. We believe that non-GAAP financial measures reflect an additional way of viewing
aspects of our operations that, when viewed with the GAAP results, provide a more complete understanding of our results of
operations and the factors and trends affecting our business. These unaudited non-GAAP financial measures are also used by
our management to evaluate financial results and to plan and forecast future periods. However, non-GAAP financial measures
should be considered as a supplement to, and not as a substitute for, or superior to, the corresponding measures calculated in
accordance with GAAP. Non-GAAP financial measures used by us may differ from the non-GAAP measures used by other
companies, including our competitors.

Adjusted EBITDA represents net income (loss) excluding the effects of interest, taxes, depreciation, amortization, stock-
based compensation and other non-recurring income or expense items, such as in-process research and development expense
and acquisition related transaction expenses, restructuring expenses, litigation exposure expenses, trial related legal costs and
litigation settlement expenses. We believe that the most directly comparable GAAP financial measure to adjusted EBITDA is
net income (loss). Adjusted EBITDA has limitations, however, and therefore, should not be considered either in isolation or as a
substitute for analysis of our results as reported under GAAP. Furthermore, adjusted EBITDA should not be considered as an
alternative to operating income (loss) or net income (loss) as a measure of operating performance or to net cash provided by
operating, investing or financing activities, or as a measure of our ability to meet cash needs.

The following is a reconciliation of adjusted EBITDA to the most comparable GAAP measure, net loss, for the years

ended December 31, 2014, 2013 and 2012 (in thousands):

Net loss

Stock-based compensation
Depreciation
Amortization of intangible assets
Amortization of acquired intangible assets
In-process research and development
Interest expense, net
Income tax provision (benefit) expense
Other (income) expense, net
Acquisition-related inventory step up
Transaction related expenses
Restructuring and other expenses
Litigation expenses and trial costs

Adjusted EBITDA

Liquidity and Capital Resources

Year Ended December 31,

2014

2013

2012

(12,882) $
4,554
12,160
1,515
4,710
527
13,606
1,087
33
—
—
742
4,779
30,831

(82,227) $
4,078
14,638
6,898
4,741
—
3,953
3,179
1,662
—
—
18,603
49,657
25,182

(15,459)
3,540
14,184
5,679
3,929
341
5,987
(1,159)
794
191
1,082
794
—
19,903

At December 31, 2014, our principal sources of liquidity consisted of cash of $19.7 million and accounts receivable, net

of $40.4 million. Based on our operating plan and cash forecast, we believe that on a combined basis, such amounts will be
sufficient to fund our projected operating requirements through at least December 31, 2015. We expect to fund our operating
expenses from available cash, cash flow from operating activity and unused availability under the revolving credit and term
loan with MidCap Financial, LLC, or MidCap.

On June 7, 2012, we entered into a credit facility, or the Credit Facility, with MidCap, which was amended and restated

on August 30, 2013 to, among other things, increase the borrowing limit from $50 million to $73 million. The Credit Facility is
due in August 2016 and consists of a revolving line of credit with a maximum borrowing base of $40 million and a $33 million
term loan. A $5 million delayed draw on the term loan was borrowed on April 1, 2014. The revolving line bears an interest rate
equal to the London Interbank Market Rate, or LIBOR, plus 6.0% and the term loan bears an interest rate of LIBOR plus 8.0%,
subject to a 9.5% floor. As of December 31, 2014, approximately $60.4 million in principal amount was outstanding under the
Credit Facility, with approximately $8 million of unused availability under the revolving line of credit.

The Credit Facility contains certain financial covenants which require us to maintain a certain fixed charge coverage ratio

and a senior leverage ratio in order to avoid default under the Credit Facility. We were in compliance with all of the covenants
of the Credit Facility as of December 31, 2014. (See “Credit Facility and Other Debt” below).

On March 15, 2014, we, Orthotec and certain other parties, including certain directors and affiliates entered into a binding

term sheet to settle the pending litigation in the Orthotec, LLC vs. Surgical S.A.S. legal matter and all other litigation matters
between Orthotec, LLC and us and our directors and affiliates. Pursuant to the binding term sheet, we have agreed to pay
Orthotec $49 million in cash payments. In accordance with the binding term sheet, we made payments totaling $1.75 million in
March 2014 and we made an additional $15.75 million payment on April 10, 2014. We will pay the remaining $31.5 million to
Orthotec in 28 quarterly installments of $1.1 million beginning in October 2014. The Company made the first quarterly
installment payment of $1.1 million, which was paid on October 1, 2014. HealthpointCapital has agreed to contribute $5
million to the $49 million settlement amount. In addition, a 7% simple interest rate will accrue on the unpaid portion of the
remaining $31.5 million that we owe, which we will pay in $1.1 million quarterly payments after the $49 million settlement
amount is paid. On September 26, 2014, we, Orthotec and certain other parties entered into a Settlement and Release
Agreement, dated as of August 13, 2014, or Orthotec Settlement Agreement, which contains substantially the same business
terms as, and superseded, the binding term sheet.

Facility Agreement, at any time until January 30, 2015, provided that the initial draw be used for a portion of the payments
made in connection with the Orthotec settlement described above, or the Litigation Satisfaction. Following such initial draw
down, we had the opportunity to draw down additional amounts under the Facility Agreement up to an aggregate of $15.0
million for working capital or general corporate purposes. We agreed to pay Deerfield, upon each disbursement of funds under
the Facility Agreement, a transaction fee equal to 2.5% of the principal amount of the funds disbursed in addition to the
issuance of additional warrants to purchase up to 10,000,000 shares of the Company's common stock to Deerfield. On March
20, 2014, we drew $20 million under the Facility Agreement and received net proceeds of $19.5 million to fund the Orthotec
settlement payment obligations due in 2014. On November 21, 2014, we drew an additional $6 million under the Facility
Agreement and received net proceeds of $5.9 million to fund future Orthotec settlement payment obligations through 2016.
The ununsed proceeds from the Facility Agreement are classified as restricted cash and may not be used for other purposes. As
of January 30, 2015, we can no longer draw down additional funds under the Facility Agreement.

Based on our current operating plan, we believe that we will be in compliance with our financial covenants under the

Credit Facility and the Facility Agreement for the foreseeable future. However, there is no assurance that we will be able to do
so. If we are not able to achieve our planned revenue or if we incur costs in excess of our forecasts, we may be required to
substantially reduce discretionary spending, and we could be in default of the Credit Facility and the Facility Agreement. Upon
the occurrence of an event of default under the Credit Facility or Facility Agreement that is not waived by MidCap or
Deerfield, they could declare the amounts outstanding under the Credit Facility and the Facility Agreement immediately due
and payable and, in the case of MidCap, refuse to extend further credit. If MidCap or Deerfield were to accelerate the
repayment of borrowings under the Credit Facility and/or the Facility Agreement, we may not have sufficient cash on hand to
repay the amounts due under the Credit Facility and/or the Facility Agreement and would have to seek to amend the terms of
the Credit Facility and/or the Facility Agreement or seek alternative financing. There can be no assurance that in the event of a
default, a waiver could be obtained from MidCap and Deerfield, that the Credit Facility and the Facility Agreement could be
successfully renegotiated or that we could modify our operations to maintain liquidity. If we are forced to seek additional
financing, which may include additional debt and/or equity financing or funding through other third party agreements, there can
be no assurance that additional financing will be available on favorable terms or available at all. Furthermore, any equity
financing may result in dilution to existing stockholders and any debt financing may include restrictive covenants.

Historically, our principal sources of cash have included customer payments from the sale of our products, proceeds from

the issuance of common and preferred stock and proceeds from the issuance of debt. Our principal uses of cash have included
cash used in operations, acquisitions of businesses and intellectual property rights, payments relating to purchases of surgical
instruments, repayments of borrowings under the Credit Facility and payments due under the Biomet settlement agreement. We
expect that our principal uses of cash in the future will be for operations, working capital, capital expenditures, and potential
acquisitions. We expect that, as our anticipated revenues grow, our sales and marketing and research and development expenses
will continue to grow and, as a result, we will need to generate significant net revenues to achieve profitability. We anticipate
that if we require additional liquidity for operations, it will be funded through borrowings under our revolving credit facility,
the incurrence of other indebtedness, additional equity financings or a combination of these potential sources of liquidity.

We will need to invest in working capital and surgical instruments (the costs of which are capitalized) in order to support
our revenue projections through the end of 2015. If we are not able to achieve our revenue forecast and cash consumption starts
to exceed forecasted consumption, we will need to adjust our investment in surgical instruments and manage our inventory to
the decreased sales volumes. If we do not make these adjustments in a timely manner, there could be an adverse impact on our
financial resources. Our revenue projections may be negatively impacted as a result of a decline in sales of our products,
including declines due to changes in our customers’ ability to obtain third-party coverage and reimbursement for procedures
that use our products, increased pricing pressures resulting from intensifying competition, and cost increases and slower
product development cycles resulting from a changing regulatory environment.

A substantial portion of our available cash funds is held in business accounts with reputable financial institutions. At
times, however, our deposits may exceed federally insured limits, and thus we may face losses in the event of insolvency of any
of the financial institutions where our funds are deposited. We did not hold any marketable securities as of December 31, 2014.

Operating Activities

We used net cash of $20.3 million from operating activities for the year ended December 31, 2014. During this period,
net cash provided by operating activities primarily consisted of a net loss of $12.9 million and a decrease in working capital
and other assets of $43.4 million partially offset by $36.0 million of non-cash costs, including amortization, depreciation, stock-
based compensation, provision for excess and obsolete inventory and interest expense related to amortization of debt discount
and issue costs. The decrease in working capital and other assets of $43.4 million consisted of decreases in accrued expenses
and other liabilities of $35.1 million and accounts payable of $1.0 million; and increases in restricted cash of $6.8 million,
inventory of $4.3 million, accounts receivable of $1.0 million and other assets of $0.3 million; partially offset by decreases in
prepaid expenses and other current assets of $4.9 million and increases in deferred revenue of $0.4 million. The increase in

restricted cash was funded by proceeds of $25.4 million from notes payable under the Facility Agreement included in financing
activities and was reduced by payments of $18.6 million made pursuant to the Orthotec Settlement Agreement, with a
corresponding decrease in accrued liabilities. Accrued expenses related to the Scient'x restructuring decreased by $8.6 million
primarily due to the payment of employee severance and related payroll taxes.

Investing Activities

We used net cash of $11.0 million in investing activities for the year ended December 31, 2014 primarily for the purchase
of $11.3 million in surgical instruments, computer equipment, leasehold improvements and manufacturing equipment, offset by
$0.3 million cash receipt for the sale of assets.

Financing Activities

Financing activities provided net cash of $30.7 million for the year ended December 31, 2014. We drew $26 million
under the Facility Agreement with Deerfield and received cash proceeds of $25.4 million, net of a transaction fee of $0.7
million, and drew a $5 million term loan under the Credit Facility with MidCap. Borrowings, net of payments under the Credit
Facility revolving line of credit, totaled $7.0 million. We made principal payments on notes payable totaling $5.8 million and
capital leases totaling $0.8 million for the year ended December 31, 2014.

Credit Facility, Facility Agreement and Other Debt

On August 30, 2013, we entered into the Credit Facility with MidCap to, among other things, increase the borrowing
limit from $50 million to $73 million. We also extended the maturity to August 2016. The Credit Facility consists of a $33
million term loan, $28 million of which was drawn at closing and a $5 million delayed draw that was drawn in April 2014, and
a revolving line of credit with a maximum borrowing base of $40 million. We used the term loan proceeds of $28 million to
repay a portion of the outstanding balance on the prior revolving line of credit. The $5 million delayed draw was borrowed on
April 1, 2014. In addition to monthly payments of interest, monthly repayments of $0.3 million of the principal for the term
loan were made beginning in October 2013, increasing to $0.5 million beginning in October 2014, and are due through
maturity, with the remaining principal due upon maturity.

The Credit Facility includes traditional lending and reporting covenants which among other things requires us to maintain

a fixed charge coverage ratio and a senior leverage ratio. The Credit Facility also includes several potential events of default,
such as payment default and insolvency conditions, which could cause interest to be charged at a rate which is up to five
percentage points above the rate effective immediately before the event of default or result in MidCap’s right to declare all
outstanding obligation immediately due and payable. We were in compliance with all of the covenants of the Credit Facility as
of December 31, 2014.

On March 17, 2014, we entered into the First Amendment to the Credit Facility, or the First Amendment, with MidCap.

The First Amendment permits, among other things, our execution of, and borrowing of loans, under the Facility Agreement
and Alphatec Spine’s granting of liens as security therefore, the payment of amounts due under the Orthotec settlement
agreement and the completion of certain conditions. The First Amendment also added a total leverage ratio financial covenant
to the Credit Facility.

On March 17, 2014, we entered into a facility agreement, or the Facility Agreement, with Deerfield Private Design Fund
II, L.P., Deerfield Private Design International II, L.P., Deerfield Special Situations Fund, L.P., and Deerfield Special Situations
International Master Fund, L.P., which we refer to collectively as "Deerfield", pursuant to which Deerfield agreed to loan us up
to $50 million, subject to the terms and conditions set forth in the Facility Agreement. Under the terms of the Facility
Agreement, we had the option, but were not required, upon certain conditions to draw the entire amount available under the
Facility Agreement, at any time until January 30, 2015, provided that the initial draw be used for a portion of the payments
made in connection with the Orthotec settlement described above, or the Litigation Satisfaction. Following such initial draw
down, we had the opportunity to draw down additional amounts under the Facility Agreement up to an aggregate of $15.0
million for working capital or general corporate purposes. We agreed to pay Deerfield, upon each disbursement of funds under
the Facility Agreement, a transaction fee equal to 2.5% of the principal amount of the funds disbursed in addition to the
issuance of additional warrants to purchase up to 10,000,000 shares of the Company's common stock to Deerfield. On March
20, 2014, we drew $20 million under the Facility Agreement and received net proceeds of $19.5 million to fund the Orthotec
settlement payment obligations due in 2014. On November 21, 2014, we drew an additional $6 million under the Facility
Agreement and received net proceeds of $5.9 million to fund future Orthotec settlement payment obligations through 2016.
The ununsed proceeds from the Facility Agreement are classified as restricted cash and may not be used for other purposes. As
of January 30, 2015, we can no longer draw down additional funds under the Facility Agreement.

On March 20, 2014, we drew $20 million and on November 21, 2014, we drew $6 million under the Facility Agreement

with Deerfield and received combined net proceeds of $25.4 million to fund the portion of the Orthotec settlement payment
obligations that are due through 2016. The amounts borrowed under the Facility Agreement are due in three equal annual
payments beginning March 20, 2017.

We have various capital lease arrangements. The leases bear interest at rates ranging from 6.6% to 9.6%, are generally

due in monthly principal and interest installments, are collateralized by the related equipment, and have various maturity dates
through October 2017. As of December 31, 2014, the balance of these capital leases, net of interest totaled $1.8 million. There
was one new lease in 2014.

Contractual obligations and commercial commitments

Total contractual obligations and commercial commitments as of December 31, 2014 are summarized in the following

table (in thousands):

Payment Due by Year

Credit Facility and term loan with MidCap

Facility Agreement with Deerfield
Interest expense

Note payable for software licenses

Note payable for insurance premiums

Capital lease obligations

Operating lease obligations

Litigation settlement obligations

Guaranteed minimum royalty obligations

New product development milestones (1)

Total

(1)

Total
$ 60,390

2015
$ 5,609

2016
$ 54,781

2017

2018

2019

— $

Thereafter
—

26,000

14,405

250

1,580

1,980

5,437

42,233

12,139

400

—

6,659

157

1,580

846

3,150

7,400

2,471

—

4,902

—

787

1,829

4,400

2,546

200

8,667

1,706

—

347

377

4,400

2,218

—

8,667

948

8,666

190

—

4,400

2,218

—

4,400

1,468

200

—

17,233

1,218

—

$ 164,814

$ 27,872

$ 69,538

$ 17,715

$ 16,306

$ 14,932

$ 18,451

This commitment represents payments in cash, and is subject to attaining certain development milestones such as FDA
approval, product design and functionality testing requirements, which we believe are reasonably likely to be achieved in
2015 through 2019.

Real Property Leases

In February 2008, we entered into a sublease agreement, or the Sublease, for office, engineering, and research and
development space in Carlsbad, California, or Building 1. The Sublease term commenced May 2008 and ends on January 31,
2016. We are obligated under the Sublease to pay base rent and certain operating costs and taxes for Building 1. Monthly base
rent payable by us was approximately $80,500 during the first year of the Sublease, increasing annually at a fixed annual rate of
2.5% to approximately $93,500 per month in the final year of the Sublease. Our rent was abated for months one through seven
of the Sublease. Under the Sublease, we were required to provide the sublessor with a security deposit in the amount of
approximately $93,500. The Sublease of Building 1 allowed us to consolidate all corporate, marketing, finance, administrative,
and research and development activities into one building.

In March 2008, we entered into a lease agreement, or the Lease, for additional office, engineering, research and
development and warehouse and distribution space in Carlsbad, California, or Building 2. The Lease term commenced on
December 1, 2008 and ends on January 31, 2017. We are obligated under the Lease to pay base rent and certain operating costs
and taxes for Building 2. The monthly base rent payable for Building 2 was approximately $73,500 during the first year of the
Lease, increasing annually at a fixed annual rate of 3.0% to approximately $93,000 per month in the final year of the Lease.
Our rent was abated for the months two through eight of the term of the Lease in the amount of $38,480. Under the Lease, we
were required to provide the lessor with a security deposit in the amount of $293,200, consisting of cash and/or one or more
letters of credit. Following our achievement of certain financial milestones, the lessor is obligated to return a portion of the
security deposit to us. The lessor provided a tenant improvement allowance of $1.1 million to assist with the configuration of
the facility to meet our business needs. We consolidated all manufacturing, distribution and warehousing activities into
Building 2 in April 2009.

Off-Balance Sheet Arrangements

As of December 31, 2014, we did not have any off-balance sheet arrangements.

Critical Accounting Policies and Estimates

Our discussion and analysis of our financial condition and results of operations is based upon our consolidated financial
statements, which have been prepared in accordance with accounting principles generally accepted in the U.S. The preparation
of these financial statements requires us to make estimates and assumptions that affect the reported amounts of assets,
liabilities, revenues, expenses and related disclosures. On an on-going basis, we evaluate our estimates and assumptions,
including those related to revenue recognition, allowances for accounts receivable, inventories, goodwill and intangible assets,
stock-based compensation and income taxes. We base our estimates on historical experience and on various other assumptions
that are believed to be reasonable under the circumstances, the results of which form the basis for making judgments about the
carrying values of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these
estimates under different assumptions conditions.

We believe the following accounting policies to be critical to the judgments and estimates used in the preparation of our

consolidated financial statements.

Revenue Recognition

We recognize revenue when all four of the following criteria are met: (i) persuasive evidence that an arrangement exists;

(ii) delivery of the products and/or services has occurred; (iii) the selling price is fixed or determinable; and (iv) collectability is
reasonably assured. In addition, we account for revenue under provisions which set forth guidelines for the timing of revenue
recognition based upon factors such as passage of title, installation, payment and customer acceptance. Determination of
criteria (iii) and (iv) are based on management’s judgment regarding the fixed nature of the fee charged for products delivered
and the collectability of those fees. Specifically, our revenue from sales of spinal and other surgical implants is recognized upon
receipt of written acknowledgment that the product has been used in a surgical procedure or upon shipment to third-party
customers who immediately accept title to such implant. Should changes in conditions cause management to determine these
criteria are not met for certain future transactions, revenues recognized for any reporting period could be adversely impacted.

Deferred Revenues

Deferred revenues consist of sales transactions where circumstances indicate that collectability is not reasonably assured

due to payment terms, regional market risks, or customer history.

Inventories

Inventories are stated at the lower of cost or market, with cost primarily determined under the first-in, first-out method.
We review the components of inventory on a periodic basis for excess, obsolete and impaired inventory, and record a reserve
for the identified items. We calculate an inventory reserve for estimated excess and obsolete inventory based upon historical
turnover and assumptions about future demand for our products and market conditions. Our biologics product inventories are
subject to demand fluctuations based on the availability and demand for alternative implant products. Our estimates and
assumptions for excess and obsolete inventory are subject to uncertainty as we are continually reviewing our existing products
and introducing new products. Increases in the reserve for excess and obsolete inventory result in a corresponding increase to
cost of revenues and establish a new cost basis for the inventory component.

Valuation of Goodwill and Intangible Assets

We assess the impairment of our goodwill and intangible assets annually in December or each quarter if business
conditions change and an earlier impairment indicator arises. This assessment requires us to make assumptions and judgments
regarding the carrying value of these assets. These assets are considered to be impaired if we determine that their carrying value
may not be recoverable based upon our assessment of the following events or changes in circumstances:

•

a determination that the carrying value of such assets cannot be recovered through undiscounted cash flows;

loss of legal ownership or title to the assets;

significant changes in our strategic business objectives and utilization of the assets; or

the impact of significant negative industry or economic trends.

If the assets are considered to be impaired, the impairment we recognize is the amount by which the carrying value of the

assets exceeds the fair value of the assets. In addition, we base the useful lives and the related amortization expense on our
estimate of the useful life of the assets. Due to the numerous variables associated with our judgments and assumptions relating
to the carrying value of our goodwill and intangible assets and the effects of changes in circumstances affecting these
valuations, both the precision and reliability of the resulting estimates are subject to uncertainty, and as additional information
becomes known, we may change our estimate, in which case the likelihood of a material change in our reported results would
increase.

We estimated the fair value in step one of the goodwill impairment model based on a combination of the income

approach which included discounted cash flows as well as the market approach that utilized our market information. The
income approach fair value measurements are categorized within Level 3 of the fair value hierarchy. Our discounted cash flows
required management judgment with respect to forecasted sales, launch of new products, gross margin, selling, general and
administrative expenses, capital expenditures and the selection and use of an appropriate discount rate and terminal rate. For
purposes of calculating the discounted cash flows, we used estimated revenue growth rates averaging between 4% and 7% for
the discrete forecast period. Cash flows beyond the discrete forecasts were estimated using a terminal value calculation, which
incorporated historical and forecasted financial trends and considered long-term earnings growth rates for publicly traded peer
companies. Future cash flows were then discounted to present value at a discount rate of 11.5%, and terminal value growth
rates of 4%. Publicly available information regarding comparable market capitalization was also considered in assessing the
reasonableness of our fair value. Our assessment resulted in a fair value that was greater than our carrying value at
December 31, 2014. In accordance with the authoritative literature, the second step of the impairment test was not required to
be performed and thus no impairment of goodwill was recorded as of December 31, 2014.

Significant management judgment is required in the forecast of future operating results that are used in our impairment

analysis. The estimates we used are consistent with the plans and estimates that we use to manage our business. Significant
assumptions utilized in our income approach model included the growth rate of sales for recently introduced products and the
introduction of anticipated new products similar to our historical growth rates. Another important assumption involved in
forecasted sales is the projected mix of higher margin U.S. based sales and lower margin non-U.S. based sales. Additionally, we
have projected an improvement in our gross margin similar to our historical improvements in gross margins, as a result of
forecasted mix in U.S. sales versus non-U.S. based sales and lower manufacturing cost per unit based on the increase in
forecasted volume to absorb applied overhead over the next 10 years. Although we believe our underlying assumptions
supporting this assessment are reasonable, if our forecasted sales, mix of product sales, growth rates of recently introduced new
products, timing of and growth rates of new product introductions, gross margin, selling, general and administrative expenses,
or the discount rate vary from our forecasts, we could be exposed to material impairment charges in the future.

Stock-Based Compensation

We account for stock-based compensation under provisions which require that share-based payment transactions with
employees be recognized in the financial statements based on their fair value and recognized as compensation expense over the
vesting period. The amount of expense recognized during the period is affected by subjective assumptions, including: estimates
of our future volatility, the expected term for our stock options, the number of options expected to ultimately vest, and the
timing of vesting for our share-based awards.

We use a Black-Scholes option-pricing model to estimate the fair value of our stock option awards. The calculation of the
fair value of the awards using the Black-Scholes option-pricing model is affected by our stock price on the date of grant as well
as assumptions regarding the following:

• Estimated volatility is a measure of the amount by which our stock price is expected to fluctuate each year during the
expected life of the award. Our estimated volatility through December 31, 2014 was based on our actual historical
volatility. An increase in the estimated volatility would result in an increase to our stock-based compensation expense.

• The expected term represents the period of time that awards granted are expected to be outstanding. Our estimated

expected term through December 31, 2014 was calculated using a weighted-average term based on historical exercise
patterns and the term from option grant date to exercise for the options granted within the specified date range. An
increase in the expected term would result in an increase to our stock-based compensation expense.

• The risk-free interest rate is based on the yield curve of a zero-coupon U.S. Treasury bond on the date the stock option

award is granted with a maturity equal to the expected term of the stock option award. An increase in the risk-free interest
rate would result in an increase to our stock-based compensation expense.

• The assumed dividend yield is based on our expectation of not paying dividends in the foreseeable future.

We use historical data to estimate the number of future stock option forfeitures. Share-based compensation recorded in

our consolidated statement of operations is based on awards expected to ultimately vest and has been reduced for estimated
forfeitures. Our estimated forfeiture rates may differ from our actual forfeitures which would affect the amount of expense
recognized during the period.

We account for stock option grants to non-employees under provisions which require that the fair value of these

instruments be recognized as an expense over the period in which the related services are rendered.

Share-based compensation expense of awards with performance conditions is recognized over the period from the date

the performance condition is determined to be probable of occurring through the time the applicable condition is met.
Determining the likelihood and timing of achieving performance conditions is a subjective judgment made by management
which may affect the amount and timing of expense related to these share-based awards. Share-based compensation is adjusted
to reflect the value of options which ultimately vest as such amounts become known in future periods. As a result of these
subjective and forward-looking estimates, the actual value of our share-based awards could differ significantly from those
amounts recorded in our financial statements.

Stock-based compensation has been classified as follows in the accompanying consolidated statements of operations (in

thousands, except per share data):

Cost of revenues
Research and development
Sales and marketing
General and administrative

Total

Effect on basic and diluted net loss per share

Income Taxes

Year Ended December 31,

2014

2013

2012

274
2,080
470
1,730
4,554
$
(0.05) $

228
719
459
2,672
4,078
$
(0.04) $

137
261
1,695
1,447
3,540
(0.04)

$
$

We account for income taxes in accordance with provisions which set forth an asset and liability approach that requires

the recognition of deferred tax assets and deferred tax liabilities for the expected future tax consequences of temporary
differences between the carrying amounts and the tax bases of assets and liabilities. Valuation allowances are established when
necessary to reduce deferred tax assets to the amount that is more likely than not expected to be realized. In making such a
determination, a review of all available positive and negative evidence must be considered, including scheduled reversal of
deferred tax liabilities, projected future taxable income, tax planning strategies, and recent financial performance.

We recognize interest and penalties related to uncertain tax positions as a component of the income tax provision.

Recent Accounting Pronouncements

In March 2013, the Financial Accounting Standards Board, or FASB, issued guidance on a parent company’s accounting

for the cumulative translation adjustment upon derecognition of a subsidiary or group of assets within a foreign entity. This new
guidance requires that the parent release any related cumulative translation adjustment into net income only if the sale or
transfer results in the complete or substantially complete liquidation of the foreign entity in which the subsidiary or group of
assets had resided. The amendments became effective for us on January 1, 2014. We adopted this guidance and the adoption did
not have any impact on our financial statements.

In April 2014, the FASB issued new guidance related to reporting discontinued operations. This new standard raises the

threshold for a disposal to qualify as a discontinued operation and requires new disclosures of both discontinued operations and
certain other disposals that do not meet the definition of a discontinued operation. The new standard is effective for fiscal years
beginning on or after December 15, 2014. We are evaluating the impact, if any, of adopting this new accounting standard on our
financial statements.

In May 2014, the FASB issued new accounting guidance related to revenue recognition. This new standard will replace

all current U.S. GAAP guidance on this topic and eliminate all industry-specific guidance. The new revenue recognition
standard provides a unified model to determine when and how revenue is recognized. The core principle is that a company
should recognize revenue to depict the transfer of promised goods or services to customers in an amount that reflects the
consideration for which the entity expects to be entitled in exchange for those goods or services. This guidance will be effective
for the Company beginning January 1, 2017 and can be applied either retrospectively to each period presented or as a

cumulative-effect adjustment as of the date of adoption. We are evaluating the impact of adopting this new accounting standard
on our financial statements.

In August 2014, the FASB issued guidance related to disclosures of uncertainties about an entity’s ability to continue as a

going concern. The guidance requires management to evaluate whether there are conditions and events that raise substantial
doubt about the entity’s ability to continue as a going concern within one year after the financial statements are issued.
Management will be required to make this evaluation for both annual and interim reporting periods and will have to make
certain disclosures if it concludes that substantial doubt exists or when its plans alleviate substantial doubt about the entity’s
ability to continue as a going concern. Substantial doubt exists when relevant conditions and events, considered in the
aggregate, indicate that it is probable that the entity will be unable to meet its obligations as they become due within one year
after the date that the financial statements are issued. The guidance is effective for annual periods ending after December 15,
2016 and for interim reporting periods starting in the first quarter 2017, with early adoption permitted. We are currently
evaluating the impact of this guidance and expect to adopt the standard for the annual reporting period ending December 31,
2016.

Item 7A.

Quantitative and Qualitative Disclosures About Market Risk

Interest Rate Risk

Our borrowings under our line of credit expose us to market risk related to changes in interest rates. As of December 31,
2014, our outstanding floating rate indebtedness totaled $60.4 million. The primary base interest rate is LIBOR. Assuming the
outstanding balance on our floating rate indebtedness remains constant over a year, a 100 basis point increase in the interest rate
would decrease pre-tax income and cash flow by approximately $0.6 million. Other outstanding debt consists of fixed rate
instruments, including notes payable and capital leases.

Foreign Currency Risk

Our foreign currency exposure continues to grow as we expand internationally. Our exposure to foreign currency

transaction gains and losses is the result of certain net receivables due from our foreign subsidiaries and customers being
denominated in currencies other than the U.S. dollar, primarily the Euro and Japanese Yen, in which our revenues and profits
are denominated. We do not currently engage in hedging or similar transactions to reduce these risks. Fluctuations in currency
exchange rates could impact our results of operations, financial position, and cash flows.

Commodity Price Risk

We purchase raw materials that are processed from commodities, such as titanium and stainless steel. These purchases
expose us to fluctuations in commodity prices. Given the historical volatility of certain commodity prices, this exposure can
impact our product costs. However, because our raw material prices comprise a small portion of our cost of revenues, we have
not experienced any material impact on our results of operations from changes in commodity prices. A 10 percent change in
commodity prices would not have a material impact on our results of operations for the year ended December 31, 2014.

Item 8.

Financial Statements and Supplementary Data

The consolidated financial statements and supplementary data required by this item are set forth at the pages indicated in

Item 15.

Item 9.

Changes in and Disagreements with Accountants on Accounting and Financial Disclosure

Not applicable.

Item 9A.

Controls and Procedures

Evaluation of Disclosure Controls and Procedures

We maintain disclosure controls and procedures that are designed to ensure that information required to be disclosed by
us in the reports we file or submit pursuant to the Exchange Act, is recorded, processed, summarized and reported within the
time periods specified in the SEC’s rules and forms and is accumulated and communicated to our management, including our
Chief Executive Officer and Chief Financial Officer, or persons performing similar functions, as appropriate, to allow for
timely decisions regarding required disclosure. In designing and evaluating the disclosure controls and procedures,
management recognizes that any controls and procedures, no matter how well designed and operated, can provide only
reasonable assurance of achieving the desired control objectives, and management is required to apply its judgment in
evaluating the cost-benefit relationship of possible controls and procedures.

Under the supervision and with the participation of our management, including our Chief Executive Officer and our
Chief Financial Officer, we carried out an evaluation of the effectiveness of the design and operation of our disclosure controls
and procedures (as such term is defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) as of the end of the period covered by
this Annual Report on Form 10-K. Based on such evaluation, our Chief Executive Officer and Chief Financial Officer
concluded that our disclosure controls and procedures were effective to ensure that information required to be disclosed by us
in reports that we file or submit under the Exchange Act, is recorded, processed, summarized and reported, within the time
periods specified in the SEC’s rules and forms, and is accumulated and communicated to our management, including our Chief
Executive Officer and Chief Financial Officer, or persons performing similar functions, as appropriate to allow timely decisions
regarding required disclosure.

Management’s Annual Report on Internal Control Over Financial Reporting

Our management, including our Chief Executive Officer and Chief Financial Officer, is responsible for establishing and

maintaining adequate internal control over financial reporting (as defined in Rules 13a-15(f)) and 15d-15(f) under the
Exchange Act.

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements.
Projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate
because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.

Our management, including our Chief Executive Officer and Chief Financial Officer, assessed the effectiveness of our

internal control over financial reporting as of December 31, 2014. In making this assessment, management used the criteria for
effective internal control over financial reporting described in “Internal Control—Integrated Framework” (2013 framework)
issued by the Committee of Sponsoring Organizations of the Treadway Commission. Based on this assessment, management
concluded that our internal control over financial reporting was effective as of December 31, 2014.

Ernst and Young LLP, an independent registered public accounting firm, who audited the consolidated financial

statements included in this Annual Report on Form 10-K, has also audited the effectiveness of our internal control over
financial reporting as stated in its report appearing elsewhere in this Annual Report on Form 10-K.

Changes in Internal Control over Financial Reporting.

There were no changes in our internal control over financial reporting identified in connection with our evaluation of
such internal control that occurred during the quarter ended December 31, 2014 that have materially affected, or are reasonably
likely to materially affect, our internal control over financial reporting.

REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

The Board of Directors and Stockholders of
Alphatec Holdings, Inc.

We have audited Alphatec Holdings, Inc.’s internal control over financial reporting as of December 31, 2014, based on
criteria established in Internal Control—Integrated Framework issued by the Committee of Sponsoring Organizations of the
Treadway Commission (2013 framework) (the COSO criteria). Alphatec Holdings, Inc.’s management is responsible for
maintaining effective internal control over financial reporting, and for its assessment of the effectiveness of internal control
over financial reporting included in the accompanying Report of Management on Internal Control over Financial Reporting.
Our responsibility is to express an opinion on the company’s internal control over financial reporting based on our audit.

We conducted our audit in accordance with the standards of the Public Company Accounting Oversight Board (United

States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether effective
internal control over financial reporting was maintained in all material respects. Our audit included obtaining an understanding
of internal control over financial reporting, assessing the risk that a material weakness exists, testing and evaluating the design
and operating effectiveness of internal control based on the assessed risk, and performing such other procedures as we
considered necessary in the circumstances. We believe that our audit provides a reasonable basis for our opinion.

A company’s internal control over financial reporting is a process designed to provide reasonable assurance regarding the

reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally
accepted accounting principles. A company’s internal control over financial reporting includes those policies and procedures
that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and
dispositions of the assets of the company; (2) provide reasonable assurance that transactions are recorded as necessary to permit
preparation of financial statements in accordance with generally accepted accounting principles, and that receipts and
expenditures of the company are being made only in accordance with authorizations of management and directors of the
company; and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or
disposition of the company’s assets that could have a material effect on the financial statements.

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements.

Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become
inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.

In our opinion, Alphatec Holdings, Inc. maintained, in all material respects, effective internal control over financial

reporting as of December 31, 2014, based on the COSO criteria.

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United

States), the consolidated balance sheets of Alphatec Holdings, Inc. as of December 31, 2014 and 2013, and the related
consolidated statements of operations, comprehensive loss, stockholders’ equity, and cash flows for each of the three years in
the period ended December 31, 2014 of Alphatec Holdings, Inc. and our report dated February 26, 2015 expressed an
unqualified opinion thereon.

/s/ Ernst & Young LLP

San Diego, California
February 26, 2015

Item 9B.

Other Information

Not applicable.

PART III

Item 10.

Directors, Executive Officers and Corporate Governance

The information required by Item 10 of this Annual Report on Form 10-K is incorporated by reference from the
discussion responsive thereto under the captions “Management,” “Corporate Governance Matters,” “Compliance with
Section 16(a) of the Securities Exchange Act of 1934,” and “Code of Conduct and Ethics” in our Proxy Statement for the 2015
Annual Meeting of Stockholders.

Item 11.

Executive Compensation

The information required by Item 11 of this Annual Report on Form 10-K is incorporated by reference from the
discussion responsive thereto under the captions “Executive Officer and Director Compensation,” “Compensation Discussion
and Analysis,” “Compensation Committee Interlocks and Insider Participation,” “Compensation Committee Report,” and
“Compensation Practices and Policies Relating to Risk Management” in our Proxy Statement for the 2015 Annual Meeting of
Stockholders.

Item 12.

Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters

The information required by Item 12 of this Annual Report on Form 10-K is incorporated by reference from the
discussion responsive thereto under the captions “Security Ownership of Certain Beneficial Owners and Management” and
“Equity Compensation Plan Information” in our Proxy Statement for the 2015 Annual Meeting of Stockholders.

Item 13.

Certain Relationships and Related Transactions, and Director Independence

The information required by Item 13 of this Annual Report on Form 10-K is incorporated by reference from the

discussion responsive thereto under the captions “Certain Relationships and Related Transactions,” “Management” and
“Corporate Governance Matters” in our Proxy Statement for the 2015 Annual Meeting of Stockholders.

Item 14.

Principal Accounting Fees and Services

The information required by Item 14 of this Annual Report on Form 10-K is incorporated by reference from the

discussion responsive thereto under the caption “Independent Public Accountants” in our Proxy Statement for the 2015 Annual
Meeting of Stockholders.

PART IV

Item 15.

Exhibits, Financial Statement Schedules

Item 15 (a) The following documents are filed as part of this Annual Report on Form 10-K:

(1) Financial Statements:

Report of Independent Registered Public Accounting Firm

Consolidated Balance Sheets

Consolidated Statements of Operations

Consolidated Statements of Comprehensive Loss

Consolidated Statements of Stockholders’ Equity

Consolidated Statements of Cash Flows

Notes to Consolidated Financial Statements

(2) Financial Statement Schedules:

Schedule II—Valuation and Qualifying Accounts

Page

F-2

F-3

F-4

F-5

F-6

F-7

F-9

F-38

All other financial statement schedules have been omitted because they are not applicable, not required or the

information required is included in the consolidated financial statements or the notes thereto.

Item 15(a)(3) Exhibits List

The following is a list of exhibits filed as part of this Annual Report on Form 10-K.

Exhibit
Number

2.1

Exhibit Description

Acquisition Agreement, dated December 17,
2009, by and among the Company and certain
shareholders of Scient’x Groupe S.A.S. and
Scient’x S.A.

Filed
with this
Report

Incorporated by
Reference herein
from Form or
Schedule
Form 8-K
(Exhibit 2.1)

Filing
Date

SEC File/
Reg.
Number

12/22/09

000-52024

2.2†

Asset Purchase Agreement, dated October 19,
2012, between the Company and Phygen, LLC

Form 10-K
(Exhibit 2.2)

03/05/12

000-52024

3.1

Restated Certificate of Incorporation

3.2

Restated Bylaws

4.1

4.2

Form of Common Stock Certificate

Stockholders’ Agreement by and among Alphatec
Holdings, Inc., HealthpointCapital Partners, LP
and certain investors, dated as of March 17, 2005

Amendment No. 2
to
Form S-1
(Exhibit 3.2)

Amendment No. 5
to
Form S-1
(Exhibit 3.4)

Form 10-K
(Exhibit 4.1)

Amendment No. 4
to
Form S-1
(Exhibit 4.2)

04/20/06

333-131609

05/26/06

333-131609

03/20/14

333-131609

05/15/06

333-131609

Exhibit
Number

Exhibit Description

Filed
with this
Report

Incorporated by
Reference herein
from Form or
Schedule
Form 10-Q
(Exhibit 10.2)

Filing
Date

SEC File/
Reg.
Number

08/04/09

000-52024

4.3

4.4

4.5

4.6

4.7

4.8

4.9

10.1

10.2

10.3†

10.4†

10.5†

Subscription Agreement dated as of June 4, 2009,
between Alphatec Holdings, Inc. and
HealthpointCapital Partners II, L.P.

Corporate Governance Agreement, dated
December 17, 2009, between the Company and
certain shareholders of Scient’x Groupe S.A.S.
and Scient’x S.A.

Registration Rights Agreement, dated March 26,
2010, by and among Alphatec Holdings, Inc. and
the other signatories thereto

Form of Subscription Agreement, dated as of
February 9, 2010, between the Company and each
of the investors in the Offering

Warrant with Silicon Valley Bank as the
Warrantholder, dated December 16, 2011

Form of Warrant to Purchase Common Stock

Registration Rights Agreement, dated March 17,
2014, by and among Alphatec Holdings, Inc.,
Deerfield Private Design Fund II, L.P., Deerfield
Private Design International II, L.P., Deerfield
Special Situations Fund, L.P. and Deerfield
Special Situations International Master Fund, L.P.
Real Property Lease Agreements
Standard Industrial Lease (Net) by and between
Alphatec Holdings, Inc. and H.G. Fenton Property
Company, dated as of January 30, 2008

Sublease Agreement by and between Alphatec
Holdings, Inc. and K2 Inc., dated as of
February 28, 2008

Loan Agreements

Amended and Restated Credit, Security and
Guaranty Agreement dated August 30, 2013 by
and among Alphatec Holdings, Inc., Alphatec
Spine, Inc., Alphatec International LLC, Alphatec
Pacific, Inc. and MidCap Funding IV, LLC

First Amendment to Amended and Restated
Credit, Security and Guaranty Agreement, dated
March 17, 2014, with MidCap Funding IV, LLC
as Administrative Agent and lender and other
lenders from time to time a party thereto

Facility Agreement, dated March 17, 2014, by and
among Alphatec Holdings, Inc., Deerfield Private
Design Fund II, L.P., Deerfield Private Design
International II, L.P., Deerfield Special Situations
Fund, L.P., and Deerfield Special Situations
International Master Fund, L.P.

Form 8-K
(Exhibit 10.1)

12/22/09

000-52024

Form 8-K
(Exhibit 4.1)

Form 8-K
(Exhibit 10.1)

Form 10-K
(Exhibit 4.8)

Form 8-K
(Exhibit 4.1)

Form 8-K
(Exhibit 4.2)

03/31/10

000-52024

02/10/10

000-52024

03/05/12

000-52024

03/19/14

000-52024

03/19/14

000-52024

Form 10-Q
(Exhibit 10.2)

Form 10-Q
(Exhibit 10.1)

05/12/08

000-52024

05/12/08

000-52024

Form 8-K
(Exhibit 10.1)

03/19/14

000-52024

Form 8-K
(Exhibit 10.3)

03/19/14

000-52024

Exhibit
Number

10.6

10.7†

10.8†

10.9†

10.10†

10.11†

10.12†

10.13†

10.14†

10.15†

10.16†

10.17†

Exhibit Description

Guaranty and Security Agreement, dated March
17, 2014 by and among Alphatec Holdings, Inc.,
Alphatec Spine, Inc., Alphatec International LLC,
Alphatec Pacific, Inc., Deerfield Private Design
Fund II, L.P., Deerfield Private Design
International II, L.P., Deerfield Special Situations
Fund, L.P., and Deerfield Special Situations
International Master Fund, L.P.

Filed
with this
Report

Incorporated by
Reference herein
from Form or
Schedule
Form 8-K
(Exhibit 10.2)

Filing
Date

SEC File/
Reg.
Number

03/19/14

000-52024

Agreements with Respect to Collaborations, Licenses, Research and Development

License Agreement by and between Alphatec
Spine, Inc. and Cross Medical Products, Inc.,
dated as of April 24, 2003

Amended License Agreement between Alphatec
Spine, Inc. and Cross Medical Products, LLC,
dated December 30, 2011

Supply Agreement by and between Alphatec
Spine, Inc. and Invibio, Inc., dated as of
October 18, 2004 and amended by Letter of
Amendment in respect of the Supply Agreement,
dated as of December 13, 2004

Letter Amendment between Alphatec Spine, Inc.
and Invibio, Inc., dated November 24, 2010

Exclusive License Agreement by and between
Alphatec Spine, Inc. and Stout Medical Group,
LP, dated as of September 11, 2007

First Amendment to the Exclusive License
Agreement, effective March 31, 2009 between
Alphatec Spine, Inc. and Stout Medical Group LP

Amendment to the Exclusive License Agreement
dated August 1, 2014 between Alphatec Spine,
Inc. and Stout Medical Group, L.P.

Amendment to Exclusive License Agreement by
and among Alphatec Spine, Inc., Alphatec
Holdings, Inc. and Progressive Spinal
Technologies LLC, dated as of January 14, 2008

Second Amendment to Exclusive License
Agreement by and among Alphatec Spine, Inc.,
Alphatec Holdings, Inc. and Progressive Spinal
Technologies LLC, dated as of January 12, 2009

Third Amendment to Exclusive License
Agreement dated as of June 30, 2009, by and
among Alphatec Holdings, Inc., Alphatec Spine,
Inc. and Progressive Spinal Technologies LLC

Fourth Amendment to Exclusive License
Agreement dated as of December 7, 2009, by and
among Alphatec Holdings, Inc., Alphatec Spine,
Inc. and Progressive Spinal Technologies LLC

Amendment No. 1
to
Form S-1
(Exhibit 10.26)

Form 10-K
(Exhibit 10.28)

Amendment No. 4
to
Form S-1
(Exhibit 10.29)

03/23/06

333-131609

03/05/12

000-52024

05/15/06

333-131609

Form 10-Q
(Exhibit 10.3)

Form 10-Q
(Exhibit 10.2)

Form 10-Q
(Exhibit 10.4)

Form 10-Q
(Exhibit 10.

05/06/11

000-52024

11/09/07

000-52024

05/05/09

000-52024

10/30/14

000-52024

Form 10-K/A
(Exhibit 10.22)

07/07/09

000-52024

Form 10-K/A
(Exhibit 10.23)

07/07/09

000-52024

Form 10-Q
(Exhibit 10.3)

08/04/09

000-52024

Form 10-K/A
(Exhibit 10.38)

04/08/10

000-52024

Exhibit
Number

10.18†

10.19†

10.20†

10.21*

10.22*

10.23*

10.24*

10.25*

10.26*

10.27*

10.28*

10.29*

10.30*

10.31*

Exhibit Description

Fifth Amendment to Exclusive License
Agreement dated as of November 30, 2010, by
and among Alphatec Holdings, Inc., Alphatec
Spine, Inc. and Progressive Spinal Technologies
LLC

Sixth Amendment to License Agreement by and
between Alphatec Spine, Inc. and Progressive
Spinal Technologies LLC, dated as of December
12, 2013

Collaboration Agreement by and among Alphatec
Spine, Inc., Elite Medical Holdings, LLC and Pac
3 Surgical Products, LLC, dated as of October 22,
2013

Agreements with Officers and Directors

Employment Agreement by and among Alphatec
Spine, Inc., Alphatec Holdings, Inc. and Michael
O’Neill, dated October 11, 2010

Employment Agreement, dated February 26,
2012, by and among Alphatec Holdings, Inc.,
Alphatec Spine, Inc, and Leslie Cross

Amendment to the Employment Agreement by
and among Les Cross, Alphatec Holdings, Inc.
and Alphatec Spine, Inc., dated May 1, 2014

Employment Agreement by and between Alphatec
Spine, Inc. and Mitsuo Asai, dated February 17,
2014

Amended and Restated Employment Agreement
by and among Alphatec Holdings, Inc., Alphatec
Spine, Inc. and Ebun S. Garner, Esq., dated
July 17, 2006

Employment Agreement by and among James M.
Corbett, Alphatec Holdings, Inc. and Alphatec
Spine, Inc., dated April 25, 2014

Employment Agreement by and among Michael
Plunkett, Alphatec Spine, Inc., and Alphatec
Holdings, Inc., dated February 17, 2014

Employment Agreement by and among Mark
Bullivant, Alphatec Spine, Inc., and Alphatec
Holdings, Inc., dated September 19, 2014

Form of Indemnification Agreement entered into
with each of the Company’s non-employee
directors

Equity Compensation Plans
Amended and Restated 2005 Employee, Director
and Consultant Stock Plan

Amendment to the Amended and Restated 2005
Employee, Director and Consultant Stock Plan

Filed
with this
Report

Incorporated by
Reference herein
from Form or
Schedule
Form 10-K
(Exhibit 10.22)

Filing
Date

SEC File/
Reg.
Number

03/04/11

000-52024

Form 10.6
(Exhibit 10.27

03/20/14

333-18790

Form 10-K
(Exhibit 10.26)

03/20/14

333-18790

Form 10-Q
(Exhibit 10.2)

Form 10-Q
(Exhibit 10.1)

11/08/10

000-52024

05/08/12

000-52024

Form 10-Q
(Exhibit 10.5)

05/01/14

000-52024

Form 10-K
(Exhibit 10.20)

03/07/08

000-52024

Form 10-Q
(Exhibit 10.1)

Form 10-Q
(Exhibit 10.4)

07/31/14

000-52024

05/01/14

000-52024

Form 10-Q
(Exhibit 10.5)

05/05/09

000-52024

Form S-8
(Exhibit 99.1)

Schedule 14A
(Appendix B)

03/23/13

333-187190

06/11/13

000-52024

Exhibit
Number

10.32*

10.33*

10.34*

10.35*

10.36*

Exhibit Description

Amendment to the Alphatec Holdings, Inc.
Amended and Restated 2005 Employee, Director
and Consultant Stock Plan

Form of Non-Qualified Stock Option Agreement
issued under the Amended and Restated 2005
Stock Plan

Form of Incentive Stock Option Agreement issued
under the Amended and Restated 2005 Stock Plan

Form of Restricted Stock Agreement issued under
the Amended and Restated 2005 Stock Plan

Form of Performance-Based Restricted Unit
Agreement issued under the Amended and
Restated 2005 Employee, Director and Consultant
Stock Plan, as amended.

10.37*

Amended 2007 Employee Stock Purchase Plan

10.38*

Summary Description of the Alphatec Holdings,
Inc. 2014 Bonus Plan

10.39†

10.40

21.1

23.1

31.1

31.2

Settlement Agreements

Settlement Agreement and General Release by
and among Alphatec Spine, Inc., Cross Medical
Products, LLC, and EBI, LLC, dated
December 30, 2011

Settlement and Release Agreement, dated as of
August 13, 2014, by and among Alphatec
Holdings, Inc. and its direct and indirect
subsidiaries and affiliates, Orthotec, LLC, Patrick
Bertranou and the other parties named therein

Subsidiaries of the Registrant and Wholly Owned
Subsidiaries of the Registrant's Subsidiaries

Consent of Independent Registered Public
Accounting Firm

Certification of Principal Executive Officer
pursuant to Section 302 of the Sarbanes-Oxley
Act of 2002

Certification of Principal Financial Officer
pursuant to Section 302 of the Sarbanes-Oxley
Act of 2002

Certification pursuant to 18 U.S.C. 1350, as
adopted pursuant to Section 906 of the Sarbanes-
Oxley Act of 2002

101.1

XBRL Instance Document**

101.2

XBRL Taxonomy Extension Schema Document**

Filed
with this
Report

Incorporated by
Reference herein
from Form or
Schedule
Form 10-Q
(Exhibit 10.1)

Filing
Date

SEC File/
Reg.
Number

10/30/14

000-52024

Form 10-K
(Exhibit 10.40)

Form 10-K
(Exhibit 10.41)

Form 10-K
(Exhibit 10.42)

Form 10-Q
(Exhibit 10.2)

Schedule 14A
(Appendix C)

Form 10-Q
(Exhibit 10.3)

03/05/13

000-52024

03/05/13

000-52024

03/05/14

000-52024

10/30/14

000-52024

06/11/13

000-52024

08/07/13

000-52024

Form 10-K
(Exhibit 10.27)

03/05/12

000-52024

Form 10-Q
(Exhibit 10.3)

10/30/14

000-52024

Exhibit
Number

Exhibit Description

Filed
with this
Report

Incorporated by
Reference herein
from Form or
Schedule

Filing
Date

SEC File/
Reg.
Number

101.3

101.4

101.5

101.6

XBRL Taxonomy Extension Calculation Linkbase
Document**

XBRL Taxonomy Extension Definition Linkbase
Document**

XBRL Taxonomy Extension Label Linkbase
Document**

XBRL Taxonomy Extension Presentation
Linkbase Document**

(*) Management contract or compensatory plan or arrangement.
(†) Confidential treatment has been granted by the Securities and Exchange Commission as to certain portions.
(**) Confidential treatment is being requested as to certain portions of this exhibit.

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused

this report to be signed on its behalf by the undersigned, thereunto duly authorized.

SIGNATURES

Dated: February 26, 2015

ALPHATEC HOLDINGS, INC.

By:
Name:
Title:

/S/ JAMES M. CORBETT
James M. Corbett

President and Chief Executive Officer

(principal executive officer)

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following

persons on behalf of the registrant and in the capacities and on the dates indicated:

Signature

Title

Date

/S/ JAMES M. CORBETT
James M. Corbett

/S/ MICHAEL O’NEILL

Michael O’Neill

/S/ LESLIE H. CROSS
Leslie H. Cross

President and Chief Executive Officer and
Director (principal executive officer)

February 26, 2015

Chief Financial Officer, Vice President and
Treasurer (principal financial officer and
principal accounting officer)

February 26, 2015

Chairman of the Board of Directors

February 26, 2015

/S/ MORTIMER BERKOWITZ III
Mortimer Berkowitz III

Chairman of the Executive Committee of the
Board of Directors

February 26, 2015

/S/ TOM C. DAVIS
Tom C. Davis

/S/ ROHIT DESAI
Rohit Desai

/S/ JOHN H. FOSTER
John H. Foster

/S/ JAMES R. GLYNN
James R. Glynn

/S/ SIRI S. MARSHALL
Siri S. Marshall

/S/ R. IAN MOLSON
R. Ian Molson

/S/ STEPHEN E. O’NEIL
Stephen E. O’Neil

Director

February 26, 2015

[This page intentionally left blank]

ALPHATEC HOLDINGS, INC.

INDEX TO CONSOLIDATED FINANCIAL STATEMENTS

Report of Independent Registered Public Accounting Firm(cid:2)

Consolidated Balance Sheets

Consolidated Statements of Operations

Consolidated Statements of Comprehensive Loss(cid:2)

Consolidated Statements of Stockholders’ Equity(cid:2)

Consolidated Statements of Cash Flows

Notes to Consolidated Financial Statements

Page

F-2

F-3

F-4

F-5

F-6

F-7

F-9

F-1

REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

The Board of Directors and Stockholders of
Alphatec Holdings, Inc.

We have audited the accompanying consolidated balance sheets of Alphatec Holdings, Inc. as of December 31, 2014 and
2013, and the related consolidated statements of operations, comprehensive loss, stockholders’ equity, and cash flows for each
of the three years in the period ended December 31, 2014. Our audits also included the financial statement schedule listed in the
Index at Item 15(a)(2). These financial statements and schedule are the responsibility of the Company's management. Our
responsibility is to express an opinion on these financial statements and schedule based on our audits.

We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United
States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial
statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and
disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a
reasonable basis for our opinion.

In our opinion, the financial statements referred to above present fairly, in all material respects, the consolidated financial
position of Alphatec Holdings, Inc., at December 31, 2014 and 2013, and the consolidated results of its operations and its cash
flows for each of the three years in the period ended December 31, 2014, in conformity with U.S. generally accepted
accounting principles. Also, in our opinion, the related financial statement schedule, when considered in relation to the basic
financial statements taken as a whole, presents fairly in all material respects the information set forth therein.

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United

States), Alphatec Holdings, Inc.’s internal control over financial reporting as of December 31, 2014, based on criteria
established in Internal Control-Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway
Commission (2013 framework) and our report dated February 26, 2015 expressed an unqualified opinion thereon.

/s/ Ernst & Young LLP

San Diego, California
February 26, 2015

F-2

ALPHATEC HOLDINGS, INC.

CONSOLIDATED BALANCE SHEETS
(In thousands, except par value data)

Assets

Current assets:
Cash

Restricted cash
Accounts receivable, net

Inventories, net

Prepaid expenses and other current assets

Deferred income tax assets

Total current assets

Property and equipment, net

Goodwill

Intangibles, net

Other assets

Total assets

Current liabilities:

Accounts payable

Accrued expenses

Deferred revenue

Liabilities and Stockholders’ Equity

Common stock warrant liabilities

Current portion of long-term debt

Total current liabilities

Long-term debt, less current portion

Other long-term liabilities

Deferred income tax liabilities

Redeemable preferred stock, $0.0001 par value; 20,000 authorized at December 31, 2014 and
2013; 3,319 shares issued and outstanding at both December 31, 2014 and 2013

Stockholders’ equity:

Common stock, $0.0001 par value; 200,000 authorized; 99,856 and 97,599 shares issued
and outstanding at December 31, 2014 and 2013, respectively

Treasury stock, 19 shares

Additional paid-in capital

Shareholder note receivable

Accumulated other comprehensive income (loss)

Accumulated deficit

Total stockholders’ equity

Total liabilities and stockholders’ equity

See accompanying notes.

F-3

December 31,

2014

2013

19,735
4,400

40,440

41,747

5,466

1,324

113,112

26,040

171,333

30,259

4,179

21,345
—

41,395

41,939

7,694

1,372

113,745

28,030

183,004

39,064

1,787

344,923

365,630

10,130

35,393

1,300

8,702

8,076

63,601

74,597

32,220

1,948

23,603

(97)

413,921

(5,000)

(11,316)

(248,564)

148,954

10,790

62,996

1,009

—

4,924

79,719

49,978

38,784

1,870

23,603

(97)

403,568

—

3,877

(235,682)

171,676

365,630

344,923

ALPHATEC HOLDINGS, INC.

CONSOLIDATED STATEMENTS OF OPERATIONS
(In thousands, except per share amounts)

Revenues

Cost of revenues

Amortization of acquired intangible assets

Gross profit

Operating expenses:

Research and development

In-process research and development

Sales and marketing

General and administrative

Amortization of acquired intangible assets

Transaction related expenses

Restructuring expenses

Litigation settlement expenses

Total operating expenses

Operating income (loss)

Other income (expense):

Interest income

Interest expense

Other expense, net

Total other income (expense)

Pretax net loss

Income tax provision (benefit)

Net loss

Net loss per basic share

Net loss per diluted share

Shares used in calculating basic net loss per share

Shares used in calculating diluted net loss per share

Year Ended December 31,

2014

2013

2012

206,980

204,724

196,278

61,834

1,736

143,410

16,799

527

77,179

43,381

2,974

—

706

—

141,566

1,844

78,669

1,733

124,322

14,190

—

76,960

47,949

3,009

—

9,665

45,982

197,755
(73,433)

10
(13,616)
(33)
(13,639)
(11,795)
1,087
(12,882) $

6
(3,959)
(1,662)
(5,615)
(79,048)
3,179
(82,227) $

(0.13) $
(0.16) $

(0.85) $
(0.85) $

97,347

97,735

96,235

70,761

1,749

123,768

14,886

341

75,177

39,939

2,180

1,082

—

133,605
(9,837)

118
(6,105)
(794)
(6,781)
(16,618)
(1,159)
(15,459)

(0.17)
(0.17)

90,218

See accompanying notes.

F-4

ALPHATEC HOLDINGS, INC.

CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS
(in thousands)

Net loss

Foreign currency translation adjustments

Comprehensive loss

Year Ended
December 31,

2014

2013

2012

(12,882) $
(15,193)
(28,075) $

(82,227) $
3,765
(78,462) $

(15,459)
2,924
(12,535)

See accompanying notes.

F-5

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-
F

ALPHATEC HOLDINGS, INC.

CONSOLIDATED STATEMENTS OF CASH FLOWS
(In thousands)

Operating activities:

Net loss
Adjustments to reconcile net loss to net cash provided by operating
activities:

Depreciation and amortization
Stock-based compensation
Interest expense related to amortization of debt discount and
debt issuance costs

In-process research and development
Provision for doubtful accounts
Provision for excess and obsolete inventory
Deferred income tax provision (benefit)
Other non-cash items

Changes in operating assets and liabilities:

Restricted cash
Accounts receivable
Inventories
Prepaid expenses and other current assets
Other assets
Accounts payable
Accrued expenses and other
Deferred revenue

Net cash (used in) provided by operating activities
Investing activities:

Purchases of property and equipment
Purchase of intangible assets
Cash paid for acquisitions
Cash received from sale of assets

Net cash used in investing activities
Financing activities:

Exercise of stock options
Borrowings under lines of credit
Repayments under lines of credit
Principal payments on capital lease obligations
Proceeds from issuance of notes payable
Principal payments on notes payable

Net cash provided by (used in) financing activities
Effect of exchange rate changes on cash
Net increase (decrease) in cash
Cash at beginning of period
Cash at end of period

Year Ended December 31,

2014

2013

2012

(12,882) $

(82,227) $

(15,459)

18,385
4,554

6,700
102
522
3,539
251
1,913

(6,750)
(1,028)
(4,348)
4,863
(276)
(1,042)
(35,130)
356
(20,271)

(11,300)
—
—
300
(11,000)

26
163,067
(156,106)
(766)
30,350
(5,837)
30,734
(1,073)
(1,610)
21,345
19,735

26,277
4,078

368
—
404
11,652
816
1,464

—
(1,940)
(4,407)
450
64
(3,853)
55,171
(510)
7,807

(14,352)
(750)
(4,000)
—
(19,102)

8
154,622
(168,855)
(434)
28,000
(2,654)
10,687
(288)
(896)
22,241
21,345

23,792
3,690

919
341
859
6,658
(3,420)
2,158

—
382
(7,853)
1,681
992
(1,799)
(1,764)
416
11,593

(15,646)
(1,750)
(2,000)
—
(19,396)

76
121,232
(99,853)
(604)
—
(12,375)
8,476
902
1,575
20,666
22,241

See accompanying notes.

F-7

ALPHATEC HOLDINGS, INC.

CONSOLIDATED STATEMENTS OF CASH FLOWS—(Continued)
(in thousands)

Year Ended December 31,

2014

2013

2012

5,885
565
1,638
1,212

$
$
$
$
— $
$
650
— $
$

11,280

3,973
1,780
1,513

$
$
$
— $
250
$
— $
— $
— $

2,592
989
1,367
2,225
1,000
—
8,856
—

Supplemental disclosure of cash flow information:

Cash paid for interest
Cash paid for income taxes
Purchases of property and equipment in accounts payable
Purchase of property and equipment through capital leases
Non-cash purchases of license agreements
Non-cash debt discount
Issuance of common stock in connection with acquisitions
Initial fair value of warrant liability

$
$
$
$
$
$
$
$

See accompanying notes.

F-8

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

1. The Company and Basis of Presentation

The Company

Alphatec Holdings, Inc. (“Alphatec”, “Alphatec Holdings” or the “Company”), through its wholly owned subsidiary,
Alphatec Spine, Inc. and its subsidiaries (“Alphatec Spine”) designs, develops, manufactures and markets products for the
surgical treatment of spine disorders. In addition to its U.S. operations, the Company also markets its products in over 50
international markets through its affiliate, Scient’x S.A.S. and its subsidiaries (“Scient’x”), via a direct salesforce in Italy and
the United Kingdom and via independent distributors in the rest of Europe, the Middle East and Africa. In South America and
Latin America the Company conducts its operations through its Brazilian subsidiary, Cibramed Productos Medicos. In Asia, the
Company markets its products through its subsidiary, Alphatec Pacific, Inc. and its subsidiaries (“Alphatec Pacific”) via a direct
sales force and independent distributors, and through distributors in other parts of Asia and Australia.

Basis of Presentation

The consolidated financial statements include the accounts of Alphatec and Alphatec Spine and its wholly owned
subsidiaries. All intercompany balances and transactions have been eliminated in the consolidated financial statements.

The accompanying consolidated financial statements have been prepared assuming that the Company will continue as a
going concern. A going concern basis of accounting contemplates the recovery of the Company’s assets and the satisfaction of
its liabilities in the normal course of business. Based on the Company’s annual operating plan, management believes that its
existing cash of $20 million combined with anticipated cash flow from operations in 2015 and other working capital of $30
million at December 31, 2014 and the Company's available borrowings under its credit facility with MidCap Financial, LLC
("MidCap") will be sufficient to fund its operating cash requirements through at least December 31, 2015.

The Company’s Amended and Restated Credit, Security and Guaranty Agreement (the “Credit Facility”) with MidCap
contains financial covenants consisting of a monthly fixed charge coverage ratio, a senior leverage ratio and a total leverage
ratio (see Note 6). Based on the Company’s board-approved current operating plan, the Company believes that it will be in
compliance with the financial covenants of the Credit Facility at least through December 31, 2015. However, there is no
assurance that the Company will be able to do so. If the Company is not able to achieve its planned revenue or incurs costs in
excess of its forecasts, it may be required to substantially reduce discretionary spending and it could be in default of the Credit
Facility which would require a waiver from MidCap. There can be no assurance that such a waiver could be obtained, that the
Credit Facility could be successfully renegotiated or that the Company can modify its operations to maintain liquidity. If the
Company is unable to obtain any required waivers or amendments, MidCap would have the right to exercise remedies specified
in the Credit Facility, including accelerating the repayment of debt obligations. The Company may be forced to seek additional
financing, which may include additional debt and/or equity financing or funding through other third party agreements. There
can be no assurances that additional financing will be available on acceptable terms or available at all. Furthermore, any equity
financing may result in dilution to existing stockholders and any debt financing may include restrictive covenants.

2. Summary of Significant Accounting Policies

Use of Estimates

The preparation of financial statements in conformity with accounting principles generally accepted in the United States

requires management to make estimates and assumptions that affect the reported amounts in the Company’s consolidated
financial statements and accompanying notes. Actual results could differ from those estimates.

Concentrations of Credit Risk and Significant Customers

Financial instruments, which potentially subject the Company to concentrations of credit risk, consist primarily of cash

and accounts receivable. The Company limits its exposure to credit loss by depositing its cash with established financial
institutions. As of December 31, 2014 a substantial portion of the Company’s available cash funds is held in business accounts.
Although the Company deposits its cash with multiple financial institutions, its deposits, at times, may exceed federally insured
limits.

F-9

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

The Company’s customers are primarily hospitals, surgical centers and distributors and no single customer represented
greater than 10 percent of consolidated revenues for any of the periods presented. Credit to customers is granted based on an
analysis of the customers’ credit worthiness and credit losses have not been significant.

Revenue Recognition

The Company derives its revenues primarily from the sale of spinal surgery implants used in the treatment of spine
disorders. The Company sells its products primarily through its direct sales force and independent distributors. Revenue is
recognized when all four of the following criteria are met: (i) persuasive evidence of an arrangement exists; (ii) delivery of the
products and/or services has occurred; (iii) the selling price is fixed or determinable; and (iv) collectability is reasonably
assured. In addition, the Company accounts for revenue under provisions which set forth guidelines for the timing of revenue
recognition based upon factors such as passage of title, installation, payment and customer acceptance.

The Company’s revenue from sales of spinal and other surgical implant products is recognized upon receipt of written

acknowledgment that the product has been used in a surgical procedure or upon shipment to third-party customers who
immediately accept title to such product.

Deferred revenues consist of sales transactions where circumstances indicate that colectibility is not reasonably assured

due to payment terms, regional market risks or customer history. The Company defers the recognition of revenue until
payments become due and cash is received from these distributors. As of December 31, 2014 and 2013, the balance in deferred
revenue totaled $1.3 million and $1.0 million, respectively.

Restricted Cash

In March and November 2014, the Company borrowed and set aside cash for the payment of a portion of the Orthotec
litigation settlement, which is subject to the terms of the facility agreement that it entered into with Deerfield on March 17,
2014. The Company classified this cash as restricted, because it may not be used for purposes other than payments of amounts
due under the Orthotec litigation settlement agreement. As of December 31, 2014, the Company had $4.4 million classified as
short-term restricted cash and $2.4 million classified as long-term restricted cash in other assets.

Accounts Receivable

Accounts receivable are presented net of allowance for doubtful accounts. The Company makes judgments as to its ability

to collect outstanding receivables and provides allowances for a portion of receivables when collection becomes doubtful.
Provisions are made based upon a specific review of all significant outstanding invoices and the overall quality and age of those
invoices not specifically reviewed. In determining the provision for invoices not specifically reviewed, the Company analyzes
historical collection experience. If the historical data used to calculate the allowance provided for doubtful accounts does not
reflect the Company’s future ability to collect outstanding receivables or if the financial condition of customers were to
deteriorate, resulting in impairment of their ability to make payments, an increase in the provision for doubtful accounts may be
required.

Inventories

Inventories are stated at the lower of cost or market, with cost primarily determined under the first-in, first-out method.

The Company reviews the components of inventory on a periodic basis for excess, obsolete and impaired inventory, and records
a reserve for the identified items. The Company calculates an inventory reserve for estimated excess and obsolete inventory
based upon historical turnover and assumptions about future demand for its products and market conditions. The Company’s
biologics inventories have an expiration based on shelf life and are subject to demand fluctuations based on the availability and
demand for alternative implant products. The Company’s estimates and assumptions for excess and obsolete inventory are
reviewed and updated on a quarterly basis. Increases in the reserve for excess and obsolete inventory result in a corresponding
increase to cost of revenues and establish a new cost basis for the part. Approximately $17.3 million and $18.4 million of
inventory was held at consigned locations as of December 31, 2014 and 2013, respectively.

Property and Equipment

Property and equipment are stated at cost, net of accumulated depreciation and amortization. Depreciation is computed

using the straight-line method over the estimated useful lives of the related assets, generally ranging from three to seven years.
Leasehold improvements and assets acquired under capital leases are amortized over the shorter of their useful lives or the
terms of the related leases.

F-10

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Goodwill and Other Intangible Assets

The Company accounts for goodwill and other intangible assets in accordance with provisions which require that

goodwill and other identifiable intangible assets with indefinite useful lives be tested for impairment at least annually. The
Company tests goodwill and intangible assets for impairment in December of each year, or more frequently if events and
circumstances warrant. These assets are impaired if the Company determines that their carrying values may not be recoverable
based on an assessment of certain events or changes in circumstances. If the assets are considered to be impaired, the Company
recognizes the amount by which the carrying value of the assets exceeds the fair value of the assets as an impairment loss.
During the year ended December 31, 2013, the Company decided that it would not continue to market an adult stem cell
product sold under the Company's private label name of PureGen. The Company also decided that it would no longer actively
market two additional products. The Company expensed $1.3 million as impairment charges in cost of goods sold in the year
ended December 31, 2013 for the write-off of intangible assets related to these products.

The Company estimated the fair value in step one of the goodwill impairment test based on a combination of the income
approach which included discounted cash flows as well as a market approach that utilized the Company’s market information.
The income approach fair value measurements are categorized within Level 3 of the fair value hierarchy. The Company’s
discounted cash flows required management judgment with respect to forecasted sales, launch of new products, gross margin,
selling, general and administrative expenses, capital expenditures and the selection and use of an appropriate discount rate and
terminal rate. For purposes of calculating the discounted cash flows, the Company used estimated revenue growth rates
averaging between 4% and 7% for the discrete forecast period. Cash flows beyond the discrete forecasts were estimated using a
terminal value calculation, which incorporated historical and forecasted financial trends and considered long-term earnings
growth rates for publicly traded peer companies. Future cash flows were then discounted to present value at a discount rate of
11.5%, and terminal value growth rate of 4%. Publicly available information regarding comparable market capitalization was
also considered in assessing the reasonableness of the Company’s fair value. The Company’s assessment resulted in a fair value
that was greater than the Company’s carrying value at December 31, 2014. In accordance with the authoritative literature, the
second step of the impairment test was not required to be performed and thus no impairment of goodwill was recorded as of
December 31, 2014.

Significant management judgment is required in the forecast of future operating results that are used in the Company’s

impairment analysis. The estimates the Company used are consistent with the plans and estimates that it uses to manage its
business. Significant assumptions utilized in the Company’s income approach model included the growth rate of sales for
recently introduced products and the introduction of anticipated new products similar to its historical growth rates. Another
important assumption involved in forecasted sales is the projected mix of higher margin U.S. based sales and lower margin non-
U.S. based sales. Additionally, the Company has projected an improvement in its gross margin, similar to its historical
improvement in gross margins, as a result of its forecasted mix in U.S. sales versus non-U.S. sales and lower manufacturing
cost per unit based on the increase in forecasted volume to absorb applied overhead over the next ten years. Although the
Company believes its underlying assumptions supporting this assessment are reasonable, if the Company’s forecasted sales, mix
of product sales, growth rates of recently introduced new products, timing of and growth rates of new product introductions,
gross margin, selling, general and administrative expenses, or the discount rate vary from its forecasts, the Company could be
exposed to material impairment charges in the future. Additionally, if the Company’s stock price decreases significantly from
the closing price on December 31, 2014, the Company may be required to perform an interim analysis in 2015 that could result
in an impairment charge.

The accounting provisions also require that intangible assets with definite useful lives be amortized over their respective

estimated useful lives and reviewed for indicators of impairment. The Company is amortizing its intangible assets, other than
goodwill, on a straight-line basis over a one to fifteen-year period.

Impairment of Long-Lived Assets

The Company assesses potential impairment to its long-lived assets when there is evidence that events or changes in
circumstances indicate that the carrying amount of an asset may not be recoverable. An impairment loss is recognized when the
carrying amount of the long-lived assets is not recoverable if it exceeds the sum of the undiscounted cash flows expected to
result from the use and eventual disposition of the asset. Any required impairment loss is measured as the amount by which the
carrying amount of a long-lived asset exceeds its fair value and is recorded as a reduction in the carrying value of the related
asset and a charge to operating results.

F-11

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Foreign Currency

The Company’s results of operations and cash flows are subject to fluctuations due to changes in foreign currency
exchange rates. The Company’s primary functional currency is the U.S. dollar, while the functional currency of the Company’s
foreign subsidiaries are the Japanese Yen, the Euro, the Brazilian Real, the British Pound and the Hong Kong dollar. Assets and
liabilities denominated in foreign currencies are translated at the rate of exchange on the balance sheet date. Revenues and
expenses are translated using the average exchange rate for the period. Net gains and losses resulting from the translation of
foreign financial statements are recorded as accumulated other comprehensive income (loss) in stockholders’ equity. Net
foreign currency gains or (losses) resulting from transactions in currencies other than the functional currencies are included in
other income (expense), net in the accompanying consolidated statements of operations. For the years ended December 31,
2014, 2013 and 2012, the Company recorded net foreign currency losses of approximately $1.0 million, $1.7 million and $0.9
million, respectively.

Warrants to Purchase Common Stock

Common stock warrants that contain compliance covenants and cash payment obligations are classified as common stock

warrant liabilities on the consolidated balance sheet. The Company records the warrant liability at fair value and adjusts the
carrying value of these common stock warrants to their estimated fair value at each reporting date with the increases or
decreases in the fair value of such warrants at each reporting date recorded as other income (expense) in the consolidated
statement of operations.

Fair Value Measurements

The carrying amount of financial instruments consisting of cash, restricted cash, trade accounts receivable, prepaid
expenses and other current assets, accounts payable, accrued expenses, accrued compensation and current portion of long-term
debt included in the Company’s consolidated financial statements are reasonable estimates of fair value due to their short
maturities. Based on the borrowing rates currently available to the Company for loans with similar terms, management believes
the fair value of long-term debt approximates its carrying value.

Authoritative guidance establishes a three-tier fair value hierarchy, which prioritizes the inputs used in measuring fair

value as follows:

Level 1:

Observable inputs such as quoted prices in active markets;

Level 2:

Level 3:

Inputs, other than the quoted prices in active markets, that are observable either directly or
indirectly; and

Unobservable inputs in which there is little or no market data, which require the reporting entity to
develop its own assumptions.

The Company does not maintain any financial instruments that are considered to be Level 1 or Level 2 instruments as of
December 31, 2014 or December 31, 2013. The Company classifies its common stock warrant liabilities within Level 3 of the
fair value hierarchy because they are valued using valuation models with significant unobservable inputs. The following table
provides a reconciliation of liabilities measured at fair value using significant unobservable inputs (Level 3) for the year ended
December 31, 2014 (in thousands):

Balance at December 31, 2013

Issuance

Changes in fair value

Balance at December 31, 2014

Common Stock
Warrant
Liabilities

—

11,280
(2,578)
8,702

Common stock warrant liabilities are measured at fair value using the Black-Scholes option pricing valuation model. The
assumptions used in the Black-Scholes option pricing valuation model for the common stock warrant liabilities were: (a) a risk-
free interest rate based on the rates for U.S. Treasury zero-coupon bonds with maturities similar to those of the remaining
contractual term of the warrants; (b) an assumed dividend yield of zero based on the Company’s expectation that it will not pay
dividends in the foreseeable future; (c) an expected term based on the remaining contractual term of the warrants; and (d) an
expected volatility based upon the Company's historical volatility over the remaining contractual term of the warrants. The

F-12

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

significant unobservable input used in measuring the fair value of the common stock warrant liabilities associated with the
Deerfield Facility Agreement (defined below) is the expected volatility. Significant increases in volatility would result in a
higher fair value measurement. The decrease in the fair value of the common stock warrant liabilities as of December 31, 2014
was primarily driven by the decrease in the Company's common stock price at December 31, 2014 as compared to the
Company's common stock price on March 17, 2014 and March 20, 2014, the dates when the common stock warrants to
purchase 10.3 million shares of the Company's common stock were issued. There was no change in the fair value of the
warrants to purchase 1.2 million shares of the Company's common stock issued on November 21, 2014.

Research and Development

Research and development expense consists of costs associated with the design, development, testing, and enhancement

of the Company’s products. Research and development costs also include salaries and related employee benefits, research-
related overhead expenses, fees paid to external service providers, and costs associated with the Company’s Scientific Advisory
Board and Executive Surgeon Panels. Research and development costs are expensed as incurred.

In-Process Research and Development

In-process research and development (“IPR&D”) consists of acquired research and development assets that are not part of

an acquisition of a business and were not technologically feasible on the date the Company acquired them and had no
alternative future use at that date or assets acquired in a business acquisition that are determined to have no alternative future
use. The Company expects all acquired IPR&D will reach technological feasibility, but there can be no assurance that
commercial viability of these products will ever be achieved. The nature of the efforts to develop the acquired technologies into
commercially viable products consists principally of planning, designing, developing and testing products in order to obtain
regulatory approvals. If commercial viability were not achieved, the Company would likely look to other alternatives to provide
these products. Until the technological feasibility of the acquired research and development assets are established, the Company
expenses these costs.

Leases

The Company leases its facilities and certain equipment and vehicles under operating leases, and certain equipment under

capital leases. For facility leases that contain rent escalation or rent concession provisions, the Company records the total rent
payable during the lease term on a straight-line basis over the term of the lease. The Company records the difference between
the rent paid and the straight-line rent as a deferred rent liability in the accompanying consolidated balance sheets.

Product Shipment Cost

Product shipment costs are included in sales and marketing expense in the accompanying consolidated statements of
operations. Product shipment costs totaled $3.7 million, $3.1 million and $2.9 million for the years ended December 31, 2014,
2013 and 2012, respectively.

Stock-Based Compensation

The Company accounts for stock-based compensation under provisions which require that share-based payment

transactions with employees be recognized in the financial statements based on their fair value and recognized as compensation
expense over the vesting period. The amount of expense recognized during the period is affected by subjective assumptions,
including: estimates of the Company’s future volatility, the expected term for its stock options, the number of options expected
to ultimately vest, and the timing of vesting for the Company’s share-based awards.

The Company uses a Black-Scholes option-pricing model to estimate the fair value of its stock option awards. The
calculation of the fair value of the awards using the Black-Scholes option-pricing model is affected by the Company’s common
stock price on the date of grant as well as assumptions regarding the following:

• Estimated volatility is a measure of the amount by which the Company’s common stock price is expected to fluctuate each
year during the expected life of the award. The Company’s estimated volatility through December 31, 2014 was based on
a weighted-average volatility of its actual historical volatility over a period equal to the expected life of the awards.

• The expected term represents the period of time that awards granted are expected to be outstanding. Through

December 31, 2014, the Company calculated the expected term using a weighted-average term based on historical
exercise patterns and the term from option date to full exercise for the options granted within the specified date range.

F-13

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

• The risk-free interest rate is based on the yield curve of a zero-coupon U.S. Treasury bond on the date the stock option

award is granted with a maturity equal to the expected term of the stock option award.

• The assumed dividend yield is based on the Company’s expectation of not paying dividends in the foreseeable future.

The Company used historical data to estimate the number of future stock option forfeitures. Share-based compensation
recorded in the Company’s consolidated statement of operations is based on awards expected to ultimately vest and has been
reduced for estimated forfeitures. The Company’s estimated forfeiture rates may differ from its actual forfeitures which would
affect the amount of expense recognized during the period.

The Company accounts for stock option grants to non-employees in accordance with provisions which require that the

fair value of these instruments be recognized as an expense over the period in which the related services are rendered.

Share-based compensation expense of awards with performance conditions is recognized over the period from the date

Valuation of Stock Option Awards

The assumptions used to compute the share-based compensation costs for the stock options granted during the years

ended December 31, 2014, 2013 and 2012 are as follows:

Risk-free interest rate
Expected dividend yield
Weighted average expected life (years)
Volatility

Compensation Costs

Year Ended December 31,

2014
1.8-1.9%
—
5.4-5.5
60-71%

2013
1.1-1.8%
—
5.3-5.5
75-76%

2012
0.9-1.2%
—
5.3-5.8
75-78%

The compensation cost that has been included in the Company’s consolidated statement of operations for all stock-based

compensation arrangements is detailed as follows (in thousands):

Cost of revenues
Research and development
Sales and marketing
General and administrative
Total

Year Ended December 31,

2014

2013

2012

274
2,080
470
1,730
4,554

228
719
459
2,672
4,078

137
261
1,695
1,447
3,540

The amounts provided above include stock-based compensation expense of $1.9 million, $1.5 million and $1.3 million

during the years ended December 31, 2014, 2013 and 2012, respectively, related to the vesting of stock options and awards
granted to non-employees under consulting agreements.

Income Taxes

The Company accounts for income taxes in accordance with provisions which set forth an asset and liability approach

that requires the recognition of deferred tax assets and deferred tax liabilities for the expected future tax consequences of
temporary differences between the carrying amounts and the tax bases of assets and liabilities. Valuation allowances are
established when necessary to reduce deferred tax assets to the amount expected to be realized. In making such determination, a
review of all available positive and negative evidence must be considered, including scheduled reversal of deferred tax
liabilities, projected future taxable income, tax planning strategies, and recent financial performance.

F-14

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

The Company recognizes interest and penalties related to uncertain tax positions as a component of the income tax

provision.

Net Loss per Share

Basic earnings per share (“EPS”) is calculated by dividing the net income or loss available to common stockholders by

the weighted average number of common shares outstanding for the period, without consideration for common stock
equivalents. Diluted EPS is computed by dividing the net income or loss available to common stockholders by the weighted
average number of common shares outstanding for the period and the weighted average number of dilutive common stock
equivalents outstanding for the period determined using the treasury-stock method. For purposes of this calculation, common
stock subject to repurchase by the Company and options are considered to be common stock equivalents and are only included
in the calculation of diluted earnings per share when their effect is dilutive. (In thousands, except per share data):

Numerator:
Net loss for basic earnings per share

Decrease in fair value of warrants

Diluted net loss applicable to common stockholders
Denominator:
Weighted average common shares outstanding

Weighted average unvested common shares subject to repurchase

Weighted average common shares outstanding—basic

Effect of dilutive securities:

Conversion of preferred stock

Options

Warrants

Weighted average common shares outstanding—diluted

Net loss per share:

Basic

Diluted

Year Ended December 31,

2014

2013

2012

(12,882) $
(2,578)
(15,460) $

(82,227) $
—
(82,227) $

98,138
(791)
97,347

—

388

97,111
(876)
96,235

—

(15,459)
—
(15,459)

90,870
(652)
90,218

—

97,735

96,235

90,218

(0.13) $
(0.16) $

(0.85) $
(0.85) $

(0.17)
(0.17)

As of December 31, 2014, 2013 and 2012, none of the outstanding shares of redeemable preferred stock were convertible

to common stock.

The weighted-average anti-dilutive securities not included in diluted net loss per share were as follows (in thousands):

Options to purchase common stock
Warrants to purchase common stock
Unvested restricted stock awards

Recent Accounting Pronouncements

Year Ended December 31,

2014

2013

2012

7,057
725
791
8,573

4,597
594
876
6,067

4,621
476
652
5,749

In March 2013, the Financial Accounting Standards Board (“FASB”) issued guidance on a parent company’s accounting

for the cumulative translation adjustment upon derecognition of a subsidiary or group of assets within a foreign entity. This new
guidance requires that the parent release any related cumulative translation adjustment into net income only if the sale or
transfer results in the complete or substantially complete liquidation of the foreign entity in which the subsidiary or group of
assets had resided. The amendments became effective for the Company beginning January 1, 2014. The Company adopted this
guidance and the adoption did not have any impact on the Company's financial statements.

F-15

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

In April 2014, the FASB issued new guidance related to reporting discontinued operations. This new standard raises the

threshold for a disposal to qualify as a discontinued operation and requires new disclosures of both discontinued operations and
certain other disposals that do not meet the definition of a discontinued operation. The new standard is effective for fiscal years
beginning on or after December 15, 2014. The Company is evaluating the impact, if any, of adopting this new accounting
standard on its financial statements.

In May 2014, the FASB issued new accounting guidance related to revenue recognition. This new standard will replace

In August 2014, the FASB issued guidance related to disclosures of uncertainties about an entity’s ability to continue as a

going concern. The guidance requires management to evaluate whether there are conditions and events that raise substantial
doubt about the entity’s ability to continue as a going concern within one year after the financial statements are issued.
Management will be required to make this evaluation for both annual and interim reporting periods and will have to make
certain disclosures if it concludes that substantial doubt exists or when its plans alleviate substantial doubt about the entity’s
ability to continue as a going concern. Substantial doubt exists when relevant conditions and events, considered in the
aggregate, indicate that it is probable that the entity will be unable to meet its obligations as they become due within one year
after the date that the financial statements are issued. The guidance is effective for annual periods ending after December 15,
2016 and for interim reporting periods starting in the first quarter 2017, with early adoption permitted. The Company is
evaluating the impact of this guidance and expects to adopt the standard for the annual reporting period ending December 31,
2016.

3. Acquisitions and Investment

Acquisition of Phygen, LLC

On November 6, 2012, the Company closed the acquisition pursuant to the Asset Purchase Agreement (the “Asset
Purchase Agreement”) with Phygen, LLC (“Phygen”), pursuant to which the Company agreed to purchase Phygen’s right, title
and interest in, and certain assets used by, Phygen in connection with the design, development, marketing and distribution of
certain of Phygen’s spinal implant products, together with the intellectual property rights, contractual rights, inventories and
certain liabilities related thereto. At the closing of the transaction, the Company issued to Phygen 4,069,087 unregistered shares
of the Company’s common stock and paid to Phygen $2 million in cash. The Company placed 1,170,960 of such unregistered
shares of the Company's common stock into an escrow account, which served as security against any potential indemnification
obligations of Phygen under the Asset Purchase Agreement for a period of 12 months following the closing. In November 2013,
the Company made a claim of 328,356 shares of the Company's common stock against the escrow shares, which were returned
to the Company in December 2013. In connection with this release of shares the Company recorded income of $0.6 million as a
reduction of general and administrative expenses in the year ended December 31, 2013. The remaining 842,604 shares of the
Company's common stock held in escrow were released to the owners of Phygen. In addition, pursuant to the Asset Purchase
Agreement, the Company paid to Phygen $4 million in cash in April 2013. In connection with the Phygen acquisition, the
Company incurred transaction related expenses of $1.1 million in the year ended December 31, 2012. The results of Phygen’s
operations are included in the consolidated financial statements from November 7, 2012.

Based on the closing price of Alphatec’s common stock of $1.69 per share on November 6, 2012, cash consideration and
contingent liabilities, the total purchase price of the Phygen acquisition of $18.5 million consisted of cash consideration of $5.9
million, fair value of Alphatec common stock of $8.9 million and contingent consideration of $3.7 million.

Pro forma supplemental financial information is not provided as the impact of the Phygen acquisition was not material to

operating results in the year ended December 31, 2014, 2013 or 2012.

F-16

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

4. Balance Sheet Details

Accounts Receivable

Accounts receivable consist of the following (in thousands):

Accounts receivable
Allowance for doubtful accounts
Accounts receivables, net

Inventories

Inventories consist of the following (in thousands):

December 31,

2014

2013

41,233
(793)
40,440

42,443
(1,048)
41,395

December 31, 2014

Reserve for
excess and
obsolete

Gross

Net

Gross

December 31, 2013

Reserve for
excess and
obsolete

Raw materials
Work-in-process
Finished goods
Inventories

5,020
1,032
57,020
63,072

— $
—
(21,325)
(21,325) $

5,020
1,032
35,695
41,747

4,375
531
60,979
65,885

— $
—
(23,946)
(23,946) $

Net

4,375
531
37,033
41,939

Property and Equipment

Property and equipment consist of the following (in thousands):

Surgical instruments
Machinery and equipment
Computer equipment
Office furniture and equipment
Leasehold improvements
Building
Land
Construction in progress

Less accumulated depreciation and amortization

Property and equipment, net

Useful lives
(in years)

December 31,

2014

2013

4
7
3
5
various
39
n/a
n/a

62,872
15,382
3,180
3,789
3,841
65
9
1,320
90,458
(64,418)
26,040

62,636
14,692
3,357
3,703
4,161
52
10
1,228
89,839
(61,809)
28,030

Total depreciation expense was $12.2 million, $14.6 million and $14.2 million for the years ended December 31, 2014,
2013 and 2012, respectively. At December 31, 2014, assets recorded under capital leases of $3.2 million were included in the
machinery and equipment balance and $0.6 million are included in the construction in progress balance. At December 31,
2013, assets recorded under capital leases of $1.8 million were included in the machinery and equipment balance and $0.6
million are included in the construction in progress balance. Amortization of assets under capital leases is included in
depreciation expense.

F-17

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Intangible Assets

Intangibles assets consist of the following (in thousands):

Developed product technology
Distribution rights
Intellectual property
License agreements
Core technology
Trademarks and trade names
Customer-related
Distribution network
Physician education programs
Supply agreement

Less accumulated amortization
Intangible assets, net

Useful lives
(in years)

December 31,

2014

2013

3-8
3
5
1-7
10
3-9
12-15
10-12
10
10

22,526
2,095
1,004
16,716
4,554
3,559
20,493
4,027
2,802
225
78,001
(47,742)
30,259

23,633
2,343
1,004
17,686
5,137
3,920
22,161
4,027
3,160
225
83,296
(44,232)
39,064

Total amortization expense was $6.2 million, $11.6 million and $9.6 million for the years ended December 31, 2014,

2013 and 2012, respectively.

During the year ended December 31, 2013, the Company decided that it would not continue to market an adult stem cell
product sold under the Company's private label name of PureGen. The Company also decided that it would no longer actively
market two additional products. The Company expensed $1.3 million as impairment charges in cost of goods sold in the year
ended December 31, 2013 for the write-off of intangible assets related to these products.

The future expected amortization expense related to intangible assets as of December 31, 2014 is as follows (in

thousands):

Year Ending December 31,
2015
2016
2017
2018
2019
Thereafter

Total

5,646
5,163
4,866
3,053
2,852
8,679

30,259

F-18

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Accrued Expenses

Accrued expenses consist of the following (in thousands):

Legal
Accounting
Severance
Restructuring
Sales milestones
Accrued taxes
Deferred rent
Royalties
Commissions
Payroll and related
Litigation settlements
Accrued interest
Other

Total accrued expenses

Goodwill

December 31,

2014

2013

967
1,262
318
531
107
1,344
785
2,129
6,152
8,291
7,393
946
5,168
35,393

2,139
928
297
9,170
1,828
1,120
1,163
2,347
6,180
9,369
22,600
—
5,855
62,996

The changes in the carrying amount of goodwill from December 31, 2013 through December 31, 2014 were as follows

(in thousands):

Balance at January 1,
Change in Phygen goodwill
Effect of foreign exchange rate on goodwill
Balance at December 31,

5. License and Consulting Agreements

2014

2013

183,004
—
(11,671)
171,333

180,838
(1,610)
3,776
183,004

OsseoFix Spinal Fracture Reduction System License Agreement

On April 16, 2009, the Company and Stout Medical Group LP (“Stout”) amended the license agreement that the parties

had entered into in September 2007 (the “License Amendment”) that provides the Company with a worldwide license to
develop and commercialize Stout’s proprietary intellectual property related to a treatment for vertebral compression fractures.
The effective date of the License Amendment is March 31, 2009. Under the License Amendment, the timing of the minimum
royalty payments has been adjusted and Stout’s ability to terminate the License Amendment was revised. Under the original
license agreement, the Company’s minimum royalty obligation began in the year ending December 31, 2009 and there are
milestones due upon attainment of sales volumes. Pursuant to the License Amendment, the minimum royalty obligation is
suspended until a licensed product obtains regulatory approval from the United States Food and Drug Administration (the
“FDA”). In addition, under the terms of the License Amendment, Stout has the ability to terminate the License Amendment if
the Company is not using commercially reasonable efforts to obtain regulatory approval to market and sell a licensed product;
provided that the Company has the right to delay such termination in exchange for making certain payments to Stout. If, during
the time period when such payments are made, the Company were to make a regulatory filing for the marketing and sale of a
licensed product, such termination will be null and void. Pursuant to the License Amendment, Stout is entitled to retain all up-
front payments that had been previously paid to it. The other material terms of the license agreement were not changed in the
License Amendment.

F-19

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

In August 2014, the Company entered a third amendment (the “Third Amendment”) to the License Agreement. Pursuant
to the Third Amendment: (i) the royalty rate paid by the Company for the net sales of licensed products is a fixed amount per
quarter through December 31, 2016; (ii) the royalty rate starting in 2017 will be increased from 7.0% to 8.5%; (ii) starting in
2017, the minimum royalty obligation is $0.2 million per year, with such minimum royalty obligation being further reduced
stating in 2018; (iii) the territory is amended so that the United States is removed from the territory in which the Company can
sell and market licensed products; (iv) all obligations of the Company to pursue a clinical trial in the United States are deleted;
and (v) all milestone payments based on the achievement of certain sales milestones are deleted. In connection with this
amendment the Company reversed the $1.7 million accrual it had recorded for the sales milestone payment into cost of goods
sold for the year ended December 31, 2014.

OsseoScrew License Agreement

In December 2007, the Company entered into an exclusive license agreement (the “OsseoScrew License Agreement”),

with Progressive Spinal Technologies LLC (“PST”), which provides the Company with an exclusive worldwide license to
develop and commercialize PST’s proprietary intellectual property related to an expanding pedicle screw with increased pull-
out strength. The financial terms of the OsseoScrew License Agreement include: (i) a cash payment payable following the
execution of the agreement; (ii) development and sales milestone payments in cash and the Company’s common stock that
began to be achieved and paid in 2008; and (iii) a royalty payment based on net sales of licensed products. The agreement
included milestone payments of $3.6 million consisting of cash and the Company’s common stock upon the completion of the
biomechanical testing, which were attained in 2009. Furthermore, the agreement includes milestone payments of $2.5 million
consisting of cash and the Company’s common stock upon market launch.

In November 2010, the Company and PST entered into a fifth amendment to the OsseoScrew License Agreement. The

fifth amendment includes (i) a milestone payment of a $1.5 million and the issuance of $1.0 million in shares of the Company’s
common stock upon market launch in Europe; and (ii) royalty payments based on net sales of licensed products with minimum
annual royalties beginning at the end of 2011. During the fourth quarter of 2010, the Company recorded an intangible asset of
$2.5 million for a milestone payment required upon market launch in Europe which consisted of the cash payment of $1.5
million and $1.0 million in shares of the Company’s common stock. The Company is amortizing this asset over seven years, the
estimated life of the product. The total number of shares of common stock which were issued on December 15, 2010, was
452,488.

On December 12, 2013, the Company and PST entered into a sixth amendment to the OsseoScrew License Agreement.
The sixth amendment provides (i) the royalty rate paid by the Company for net sales of licensed products is increased; (ii) the
territory is amended so that the United States is removed from the territory in which the Company can sell and market licensed
products, and such rights are non-exclusive in Russia and the People’s Republic of China; (iii) all milestone payments based on
the achievement of certain sales milestones are deleted; and (iv) a $0.3 million milestone payment to be paid upon the
achievement of regulatory approval of a licensed product in the People’s Republic of China was added. In connection with this
amendment, the Company reversed the $0.6 million accrual it had recorded for the sales milestone payment into cost of goods
sold for the year ended December 31, 2013.

License Agreement with Helix Point, LLC

In February 2009, the Company entered into a license agreement (the “Helifuse/Helifix License Agreement”) with Helix
Point, LLC (“Helix Point”) that provides the Company with a worldwide exclusive license (excluding the People’s Republic of
China) to develop and commercialize Helix Point’s proprietary intellectual property related to a device for the treatment of
spinal stenosis. The financial terms of the Helifuse/Helifix License Agreement include: (i) a cash payment of $0.2 million
payable following the execution of the Helifuse/Helifix License Agreement; (ii) the issuance of $0.4 million of shares of the
Company’s common stock following the execution of the Helifuse/Helifix License Agreement; (iii) development and sales
milestone payments in cash and the Company’s common stock; and (iv) a royalty payment based on net sales of licensed
products, with minimum annual royalties beginning in the year after the first commercial sale of a licensed product. During the
third quarter of 2010, the Company recorded an intangible asset of $0.2 million for the assets received as this product is cleared
for sale in Europe and technological feasibility is considered to have been achieved. The Company is amortizing this asset over
seven years, the estimated life of the product.

F-20

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

License Agreement with International Spinal Innovations, LLC

In June 2009, the Company entered into a cross license agreement (the “ISI License Agreement”) with International
Spinal Innovations, LLC (“ISI”) that provides the Company with a worldwide license to develop and commercialize ISI’s
proprietary intellectual property related to a stand-alone anterior lumbar interbody fusion device. The financial terms of the ISI
License Agreement include: (i) the issuance of 260,000 shares of the Company’s common stock following the execution of the
ISI License Agreement; (ii) sales milestone payments in cash that could begin to be achieved and paid in 2016; and (iii) a
royalty payment based on net sales of licensed products. In 2012, the Company entered into an amended agreement that
established a minimum royalty payment amount that began in 2012.

Distribution Agreement with Parcell Spine, LLC

In January 2010, the Company entered into an exclusive distribution agreement (the “Parcell Agreement”) with Parcell
Spine, LLC (“Parcell Spine”), which provides the Company with the exclusive right to distribute Parcell Spine’s proprietary
adult stem cells for the treatment of spinal disorders under either Parcell’s trademarks or Alphatec Spine’s private label. The
financial terms of the Parcell Agreement include: (i) a cash payment of $0.5 million payable following the execution of the
Parcell Agreement; (ii) a milestone payment consisting of $1.0 million in cash and the issuance of $1.0 million of shares of the
Company’s common stock following the successful completion of a pre-clinical study; and (iii) sales milestone payments in
cash and the Company’s common stock. During the first quarter of 2010, the Company recorded an IPR&D charge of $0.5
million for the initial cash payment. During the third quarter of 2010, the pre-clinical study milestone was achieved and the
Company recorded an IPR&D charge totaling $2.0 million, which consisted of a cash payment of $1.0 million and the issuance
of $1.0 million worth of the Company’s common stock. The amounts were expensed as the technological feasibility associated
with the IPR&D had not been established since the final prototype of the device had not been completed, additional items
subject to risk of completion were necessary to comply with regulatory requirements and no alternative future use exists. The
total number of shares of common stock, which were issued in accordance with the agreement for the achievement of a
development milestone, was 465,116. In addition, during the third quarter of 2010, the Company recorded an intangible asset of
$1.5 million for a milestone payment required upon market launch when the product became commercially ready for sale which
consisted of a cash payment of $0.5 million and $1.0 million worth of the Company’s common stock. The Company is
amortizing this asset over seven years, the estimated life of the product. The total number of shares of common stock, which
were issued in accordance with the agreement for the achievement of a development milestone in September 2010, was
476,190.

During the year ended December 31, 2013, the Company decided that it would not continue to sell its PureGen product,

which is currently the only product commercialized by the Company under the Parcell Agreement. During the year ended
December 31, 2013, the Company expensed $0.9 million as impairment charges in cost of goods for the write-off of intangible
assets related to the Parcell Agreement and expensed $2.6 million related to the write-off of inventory and certain prepaid assets
in cost of goods sold.

License Agreement with R Tree Innovations LLC

In September 2010, the Company entered into a License Agreement (the “R Tree License Agreement”) with R Tree
Innovations LLC (“R Tree”) that provides the Company with a worldwide license to develop and commercialize R Tree’s
proprietary intellectual property related to its Epicage interbody fusion device and related instrumentation. The financial terms
of the R Tree License Agreement include: (i) a cash payment of $0.8 million and the issuance of $0.5 million of the Company’s
common stock following the execution of the R Tree License Agreement; (ii) development and sales milestone payments in
cash that could begin to be achieved and paid in 2013; and (iii) a royalty payment based on net sales of licensed products.
During the third quarter of 2010, the Company recorded an intangible asset of $1.3 million following the execution of the R
Tree License Agreement. In November 2012, the Company and R Tree entered into an amendment to the R Tree License
Agreement (the “R Tree Amendment”). In connection with the R Tree Amendment, the Company made a cash payment of $0.3
million and issued $0.2 million of its common stock to R Tree. The total consideration of $0.5 million was recorded as an
intangible asset. The Company is amortizing the intangible asset over seven years, the estimated life of the product. The total
number of shares of common stock, which were issued in accordance with the R Tree License Agreement and the R Tree
Amendment was 367,044. In October 2013, another milestone was reached and the Company made a $0.3 million cash
payment and issued $0.2 million worth of its common stock to R Tree. The total consideration of $0.5 million was recorded as
an intangible asset.

F-21

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Cervical Interbody Spacer Supply Agreement

In October 2012, the Company entered into a supply agreement with a third party supplier whereby the Company
acquired exclusive worldwide distribution rights to sell an anchored, fully retractable cervical inter-body spacer (the “Cervical
Spacer Supply Agreement”). The Company was required to make up-front payments totaling $1.0 million upon the execution of
the Cervical Spacer Supply Agreement. The $1.0 million up-front payments were capitalized as an intangible asset and is being
amortized over the 7-year term of the Cervical Spacer Supply Agreement. Additionally, the Company was required to meet
certain minimum purchase requirements of up to $5.9 million per year to maintain its exclusive distribution rights. In
September 2014, the Company entered into an amendment to the Cervical Spacer Supply Agreement that eliminated the
minimum purchase requirements and modified the distribution rights to non-exclusive.

Asset Purchase Agreement

In July 2014, the Company entered into an asset purchase and product development services agreement (the "Asset

Agreement") whereby the Company purchased rights to the conceptual design for an intervertebral implant device. The
financial terms of the Agreement include payments in cash and the Company's common stock upon achievement of various
milestones. The Company accounted for this arrangement as an asset acquisition. In the year ended December 31, 2014, the
Company made cash payments totaling $0.2 million and issued 72,992 shares of the Company's common stock valued at $0.1
million. The Company recognized the cash and stock payments of $0.3 million as in-process research and development expense
in the year ended December 31, 2014.

6. Debt

MidCap Loan and Security Agreement

On August 30, 2013, the Company entered into the Amended Credit Facility with MidCap. The Amended Credit Facility

amended and restated the prior credit facility that the Company had with MidCap (the "Prior Credit Facility").

Pursuant to the Amended Credit Facility, the Company increased the borrowing limit from $50 million to $73 million.
The Company also extended the maturity to August 2016. The Amended Credit Facility consists of a $33 million term loan, $28
million of which was drawn at closing and the remaining $5 million of which was drawn in April 2014, and a revolving line of
credit with a maximum borrowing base of $40 million, of which $31.8 million was outstanding at December 31, 2014. The
Company used the term loan proceeds of $28 million drawn at closing to repay a portion of the outstanding balance on the prior
revolving line of credit.

The term loan interest rate is priced at the London Interbank Offered Rate ("LIBOR") plus 8.0%, subject to a 9.5% floor,

and the revolving line of credit interest rate bears interest at LIBOR plus 6.0%, reset monthly. At December 31, 2014, the
revolving line of credit carries an interest rate of 6.2% and the term loan carries an interest rate of 9.5%. The borrowing base is
determined, from time to time, based on the value of domestic eligible accounts receivable and domestic eligible inventory. As
collateral for the Amended Credit Facility, the Company granted MidCap a security interest in substantially all of its assets,
including all accounts receivable and all securities evidencing its interests in its subsidiaries. In addition to monthly payments
of interest, monthly repayments of $0.3 million of the principal for the term loan were made beginning in October 2013,
increasing to $0.5 million beginning in October 2014, and are due through maturity, with the remaining principal due upon
maturity.

In connection with the execution of the Amended Credit Facility, the Company incurred approximately $0.4 million in

costs, which were capitalized as debt issuance costs within the consolidated balance sheet as of December 31, 2014. At
December 31, 2014, $0.4 million remains as unamortized debt issuance costs related to the prior and Amended Credit Facility
within the consolidated balance sheet, which will be amortized over the remaining term of the Amended Credit Facility.

On June 7, 2012, the Company entered into the Prior Credit Facility with MidCap, which permitted the Company to
borrow up to $40 million under a revolving line of credit and included an option to increase the borrowing base to $50 million
with the prior consent of MidCap. As collateral for the Prior Credit Facility, the Company granted MidCap a security interest in
substantially all of its assets, including all accounts receivable and all securities evidencing its interests in its subsidiaries.

Upon execution of the Prior Credit Facility, the Company drew $34.3 million on the Credit Facility to pay off its existing
term loan with Silicon Valley Bank (“SVB”) totaling $8.1 million and its existing line of credit with SVB totaling $17.6 million
(collectively the “SVB Credit Facility”). The Company paid early termination and other fees to SVB associated with the SVB
Credit Facility of $2.3 million and wrote-off $0.6 million of unamortized debt issuance and debt discount costs related to the
SVB Credit Facility. The total loss on extinguishment of debt costs of $2.9 million is included in interest expense in the year

F-22

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

ended December 31, 2012. The Company paid an up-front commitment fee to MidCap of $0.2 million and debt issuance costs
of $0.2 million, which were capitalized as deferred debt issuance costs.

The Amended Credit Facility includes traditional lending and reporting covenants including a fixed charge coverage ratio,

a senior leverage ratio and a total leverage ratio to be maintained by the Company. The Amended Credit Facility also provides
for several potential events of default, such as payment default and insolvency conditions, which could cause interest to be
charged at a rate which is up to five percentage points above the rate effective immediately before the event of default or result
in MidCap’s right to declare all outstanding obligations immediately due and payable.

In January 2013, the Company entered into a limited waiver and limited consent agreement with MidCap (the “Waiver”).
Under the Waiver, MidCap waived certain provisions of the Prior Credit Facility in connection with the acquisition of the assets
of Phygen, LLC ("Phygen") and related to the maintenance of cash balances in the U.S. In February 2013, the Company and
MidCap entered into a first amendment to the Prior Credit Facility (the "First Amendment to the Credit Facility”). The First
Amendment to the Credit Facility allowed the Company to exclude payments related to the Phygen acquisition and the
settlement agreement with Cross Medical Products, LLC (“Cross”) from calculation of the fixed charge coverage ratio and the
senior leverage ratio. In conjunction with the First Amendment to the Credit Facility, the Company paid MidCap a fee of $0.1
million. In July 2013, the Company entered into a second limited waiver and limited consent agreement with MidCap (the
“Second Waiver”). Under the Second Waiver, MidCap waived certain provisions of the Prior Credit Facility related to the
maintenance of cash balances in the U.S. for past periods through September 30, 2013. On August 30, 2013, the Company
entered into the Amended Credit Agreement with MidCap.

On March 17, 2014, the Company entered into a first amendment to the Amended Credit Facility with MidCap (the "First

Amendment to the Amended Credit Facility"). Under the First Amendment to the Amended Credit Facility, MidCap gave the
Company its consent to enter into the Facility Agreement (defined below) and make settlement payments in connection with the
Orthotec litigation. The First Amendment to the Amended Credit Facility also added a total leverage ratio financial covenant.
The Company was in compliance with all of the covenants of the Amended Credit Facility as of December 31, 2014.

During the year ended December 31, 2014, the Company repaid $156.1 million and drew an additional $163.1 million on

its working capital line of credit under the Amended Credit Facility. The balance of the line of credit and the term loan as of
December 31, 2014 was $31.8 million and $28.6 million, respectively. Amortization of the debt discount and debt issuance
costs, accretion of the finance charge and non-cash extinguishment of debt costs, which were recorded as non-cash interest
expense, totaled $0.3 million, $0.2 million and $0.9 million for the years ended December 31, 2014, 2013 and 2012,
respectively. Interest expense for the term loans and the Company’s working capital line of credit, excluding debt discount and
debt issuance cost amortization, accretion of the additional finance charge and extinguishment of debt costs, totaled $5.3
million, $3.6 million and $2.6 million for the years ended December 31, 2014, 2013 and 2012, respectively.

Deerfield Facility Agreement

On March 17, 2014, the Company entered into a facility agreement (the “Facility Agreement”) with Deerfield, pursuant to

which Deerfield agreed to loan the Company up to $50 million, subject to the terms and conditions set forth in the Facility
Agreement. Under the terms of the Facility Agreement, the Company had the option, but was not required, upon certain
conditions to draw the entire amount available under the Facility Agreement, at any time until January 30, 2015 (the “Draw
Period”), provided that the initial draw be used for a portion of the payments made in connection with the Orthotec settlement
described in Note 7 below. Following such initial draw down, the Company was permitted to draw down additional amounts
under the Facility Agreement up to an aggregate $15 million for working capital or general corporate purposes in $2.5 million
increments until the end of the Draw Period. The Company agreed to pay Deerfield, upon each disbursement of funds under the
Facility Agreement, a transaction fee equal to 2.5% of the principal amount of the funds disbursed. Amounts borrowed under
the Facility Agreement bear interest at a rate of 8.75% per annum and are payable on the third, fourth and fifth anniversary date
of the first amount borrowed under the Facility Agreement, with the final payment due on March 20, 2019.

The Facility Agreement also contains various representations and warranties, and affirmative and negative covenants,

customary for financings of this type, including restrictions on the ability of the Company and its subsidiaries to incur
additional indebtedness or liens on its assets, except as permitted under the Facility Agreement. As security for our repayment
of our obligations under the Facility Agreement, the Company granted to Deerfield a security interest in substantially all of our
property and interests in property, which is subordinated to the security interest granted under the Amended Credit Facility.

F-23

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

In connection with the execution of the Facility Agreement on March 17, 2014, the Company issued to Deerfield warrants

to purchase an aggregate of 6,250,000 shares of the Company’s common stock (the “Initial Warrants”) (See Note 9).
Additionally, the Company agreed that upon each disbursement under the Facility Agreement, the Company would issue to
Deerfield warrants to purchase up to 10,000,000 shares of the Company’s common stock, in proportion to the amount of draw
compared to the total $50 million facility (the "Draw Warrants") (See Note 9).

On March 20, 2014, the Company made an initial draw of $20 million under the Facility Agreement and received net

proceeds of $19.5 million to fund the portion of the Orthotec settlement payment obligations that were due in 2014. The $0.5
million transaction fee was recorded as a debt discount and is being amortized over the term of the draw, which ends March 20,
2019. In connection with this borrowing, the Company issued Draw Warrants to purchase 4,000,000 shares of common stock,
which were valued at $4.7 million and recorded as a debt discount and is being amortized over the term of the draw.
Additionally, $2.3 million of the value of the Initial Warrants was reclassified as a debt discount and is being amortized through
interest expense over the term of the debt using the effective interest method.

On November 21, 2014, the Company made a second draw of $6 million under the Facility Agreement and received net

proceeds of $5.9 million to fund the portion of the Orthotec settlement payments through 2016. The $0.2 million transaction fee
was recorded as a debt discount and is being amortized over the remaining term of the draw, which ends March 20, 2019. In
connection with this borrowing, the Company issued Draw Warrants to purchase 1,200,000 share of common stock, which were
valued at $0.9 million and recorded as a debt discount and is being amortized over the term of the debt using the effective
interest method.

Orthotec settlement payments of $18.6 million were made in the year ended December 31, 2014, leaving remaining
proceeds of $4.4 million, which are classified as short-term restricted cash and $2.4 million, which are classified as long-term
restricted cash under other assets borrowed under the Facility Agreement, as their use is limited under the terms of the Facility
Agreement for the payments of amounts due under the Orthotec litigation settlement agreement. The amounts borrowed under
the Facility Agreement, which total $26.5 million in principal and accrued interest as of December 31, 2014, are due in three
equal annual payments beginning March 20, 2017. Additionally, $0.2 million of the value of the Initial Warrants was
reclassified as a debt discount and is being amortized through interest expense over the term of the debt using the effective
interest method.

Other Debt Agreements

The Company has various capital lease arrangements. The leases bear interest at rates ranging from 6.6% to 9.6%, are

generally due in monthly principal and interest installments, are collateralized by the related equipment, and have various
maturity dates through October 2017.

Long-term debt consists of the following (in thousands):

Amended Credit Facility with MidCap
Facility Agreement with Deerfield
Note payable related to software license purchases
Financing agreements for premiums on insurance policies

Total

Add: capital leases (See Note 7)
Less: debt discount

Total

Less: current portion of long-term debt

Total long-term debt, net of current portion

December 31,

2014

2013

60,390
26,000
250
1,580
88,220
1,784
(7,331)
82,673
(8,076)
74,597

52,081
—
58
1,427
53,566
1,336
—
54,902
(4,924)
49,978

F-24

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Principal payments on debt are as follows as of December 31, 2014 (in thousands):

Year Ending December 31,
2015
2016
2017
2018
2019
Thereafter

Total

Add: capital lease principal payments
Less: debt discount

Total

Less: current portion of long-term debt

Long-term debt, net of current portion

7. Commitments and Contingencies

Leases

7,346
54,874
8,667
8,667
8,666
—

88,220
1,784
(7,331)

82,673
(8,076)

74,597

During the first quarter of 2008, the Company entered into a lease agreement and sublease agreement in order to
consolidate the use and occupation of its then existing premises into two adjacent facilities, as described below. The Company
also leases certain equipment and vehicles under operating leases which expire on various dates through 2018, and certain
equipment under capital leases which expire on various dates through 2017.

In February 2008, the Company entered into a sublease agreement (the “Sublease”), for office, engineering, and research

and development space. The Sublease term commenced May 2008 and ends on January 31, 2016.

The Company is obligated under the Sublease to pay base rent and certain operating costs and taxes for the building.

Monthly base rent payable by the Company was approximately $80,500 during the first year of the Sublease, increasing
annually at a fixed annual rate of 2.5% to approximately $93,500 per month in the final year of the Sublease. The Company’s
rent was abated for months one through seven of the Sublease. At the sublease inception, the Company paid a security deposit
in the amount of approximately $93,500.

In March 2008, the Company entered into a lease agreement (the “Lease”) for additional office, engineering, research and
development and warehouse and distribution space. The Lease term commenced on December 1, 2008 and ends on January 31,
2017. The Company is obligated under the Lease to pay base rent and certain operating costs and taxes for the building. The
monthly base rent payable by the Company was approximately $73,500 during the first year of the Lease, increasing annually at
a fixed annual rate of 3.0% to approximately $93,000 per month in the final year of the Lease. The Company’s rent was abated
for the months two through eight of the term of the Lease in the amount of $38,480. At the lease inception, the Company paid a
security deposit in the amount of approximately $293,200 consisting of cash and two letters of credit. In the event the Company
achieves certain financial milestones, the lessor is obligated to return a portion of the security deposit to the Company. The
lessor provided a tenant improvement allowance of $1.1 million to assist with the configuration of the facility to meet the
Company’s business needs.

F-25

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Future minimum annual lease payments under the Company’s operating and capital leases are as follows (in thousands):

Year ending December 31,
2015
2016
2017
2018
2019
Thereafter

Less: amount representing interest
Present value of minimum lease payments
Current portion of capital leases
Capital leases, less current portion

Operating

Capital

3,150
1,829
377
73
8
—
5,437

846
787
347
—
—
—
1,980
(196)
1,784
(730)
1,054

Rent expense under operating leases for the years ended December 31, 2014, 2013 and 2012 was $3.4 million, $3.8

million and $3.7 million, respectively.

Litigation

On March 15, 2014, the Company, Orthotec, LLC and certain other parties, including certain directors and affiliate of the
Company, entered into a binding term sheet (the "Binding Term Sheet") to resolve the Orthotec, LLC v. Surgiview, S.A.S, et al.
matter in the Superior Court of California, Los Angeles County and related litigation matters (the "Orthotec Settlement").
Pursuant to the terms contained in the Binding Term Sheet, the Company agreed to pay Orthotec, LLC $49 million in cash,
including initial cash payments totaling $1.75 million, which the Company previously paid in March 2014, and an additional
lump sum payment of $15.75 million, which the Company previously paid in April 2014. The Company agreed to pay the
remaining $31.5 million in 28 quarterly installments of $1.1 million and then one additional quarterly installment of $700,000,
commencing October 1, 2014. The Company made the first quarterly installment payment of $1.1 million, which was paid on
October 1, 2014. The Company has the right to prepay the amounts due without penalty. In addition, the unpaid balance of the
amounts due will accrue interest at the rate of 7 percent per year beginning May 15, 2014 until the amounts due are paid in full.
The accrued but unpaid interest will be paid in quarterly installments of $1.1 million (or the full amount of the accrued but
unpaid interest if less than $1.1 million) following the full payment of the $31.5 million in quarterly installments described
above. No interest will accrue on the accrued interest. The Binding Term Sheet provided for mutual releases of all claims in the
Orthotec, LLC v. Surgiview, S.A.S, et al. matter in the Superior Court of California, Los Angeles County and all other related
litigation matters involving the Company and its directors and affiliates.

On September 26, 2014, the Company entered into a Settlement and Release Agreement, dated as of August 13, 2014, by

and among the Company and its direct subsidiaries, including Alphatec Spine, Inc., Alphatec Holdings International C.V.,
Scient'x S.A.S. and Surgiview S.A.S.; HealthpointCapital, LLC, HealthpointCapital Partners, L.P., HealthpointCapital Partners
II, L.P., John H. Foster and Mortimer Berkowitz III; and Orthotec, LLC and Patrick Bertranou, (the "Settlement Agreement").
The Settlement Agreement contains substantially the same business terms as the Binding Term Sheet set forth above, and
supersedes the Binding Term Sheet.

On August 10, 2010, a purported securities class action complaint was filed in the United States District Court for the

Southern District of California on behalf of all persons who purchased the Company's common stock between December 19,
2009 and August 5, 2010 against the Company and certain of its directors and officers alleging violations of the Securities
Exchange Act of 1934, as amended (the "Exchange Act"), and Rule 10b-5 promulgated thereunder. On February 17, 2011, an
amended complaint was filed against the Company and certain of its directors and officers adding alleged violations of the
Securities Act of 1933 (the "Securities Act"), as amended. HealthpointCapital, Jefferies & Company, Inc., Canaccord Adams,
Inc., Cowen and Company, Inc., and Lazard Capital Markets LLC are also defendants in this action. The complaint alleges that
the defendants made false or misleading statements and failed to disclose material facts about the Company’s business,
financial condition, operations and prospects, particularly relating to the Scient’x transaction and the Company's financial
guidance following the closing of the acquisition. The complaint seeks unspecified monetary damages, attorneys’ fees, and
other unspecified relief. The Company filed a motion to dismiss the amended complaint on April 18, 2011. The district court
granted the motion to dismiss with leave to amend on March 22, 2012. On April 19, 2012, the lead plaintiff filed a Second
Amended Complaint alleging violations of Sections 10(b) and 20(a) of the Exchange Act and violations of Section 11, 12(a)(2),

F-26

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

and 15 of the Securities Act against the same named defendants. On May 3, 2012, the Company filed a motion to dismiss the
Second Amended Complaint. The district court granted that motion without leave to amend and entered final judgment in the
Company’s favor on March 28, 2013. On April 17, 2013, the lead plaintiff filed a notice of appeal to the United States Court of
Appeals for the Ninth Circuit. The appeal has been fully briefed. The Company believes that the claims are without merit and it
intends to vigorously defend itself against this complaint. However, the outcome of the litigation cannot be predicted at this
time and any outcome that is adverse to the Company, regardless of who the defendant is, could have a significant adverse
effect on its financial condition and results of operations.

On August 25, 2010, an alleged shareholder of the Company filed a derivative lawsuit in the Superior Court of California,

San Diego County, purporting to assert claims on behalf of the Company against all of its directors and certain of its officers
and HealthpointCapital. Following the filing of this complaint, similar complaints were filed in the same court and in the U.S.
District Court for the Southern District of California against the same defendants containing similar allegations. The complaint
filed in federal court was dismissed by the plaintiff without prejudice in July 2011. The state court complaints were
consolidated into a single action and the Company was named as a nominal defendant in the consolidated action. Each
complaint alleges that the Company’s directors and certain of its officers breached their fiduciary duties to the Company related
to the Scient’x transaction, and allegedly made false statements that led to unjust enrichment of HealthpointCapital and certain
of the Company’s directors. The complaints seek unspecified monetary damages and an order directing the Company to adopt
certain measures purportedly designed to improve its corporate governance and internal procedures. On January 8, 2014, the
parties reached an agreement in principle to resolve all claims in exchange for corporate governance reforms and payment of
attorneys’ fees in the amount of $5.25 million, to be paid by the Company’s and HeathpointCapital’s respective insurance
carriers. The final settlement was approved by the Court in August 2014.

At December 31, 2014, the probable outcome of any of the aforementioned litigation matters that have not reached a

settlement cannot be determined nor can the Company estimate a range of potential loss. Accordingly, in accordance with the
authoritative guidance on the evaluation of contingencies, the Company has not recorded an accrual related to any litigation
matters that have not reached a settlement. The Company is and may become involved in various other legal proceedings
arising from its business activities. While management does not believe the ultimate disposition of the above matters that have
not yet been settled will have a material adverse impact on the Company’s consolidated results of operations, cash flows or
financial position, litigation is inherently unpredictable, and depending on the nature and timing of these proceedings, an
unfavorable resolution could materially affect the Company’s future consolidated results of operations, cash flows or financial
position in a particular period.

Royalties

The Company has entered into various intellectual property agreements requiring the payment of royalties based on the
sale of products that utilize such intellectual property. These royalties primarily relate to products sold by Alphatec Spine and
are calculated either as a percentage of net sales or in one instance on a per-unit sold basis. Royalties are included on the
accompanying consolidated statement of operations as a component of cost of revenues.

8. Redeemable Preferred Stock and Stockholders’ Equity

Redeemable Preferred Stock

The Company issued shares of redeemable preferred stock in connection with its initial public offering in June 2006. As

of December 31, 2014, the redeemable preferred stock carrying value was $23.6 million and there were 20 million shares of
redeemable preferred stock authorized. The redeemable preferred stock is not convertible into common stock but is redeemable
at $9.00 per share, (i) upon the Company’s liquidation, dissolution or winding up, or the occurrence of certain mergers,
consolidations or sales of all or substantially all of the Company’s assets, before any payment to the holders of the Company’s
common stock, or (ii) at the Company’s option at any time. Holders of redeemable preferred stock are generally not entitled to
vote on matters submitted to the stockholders, except with respect to certain matters that will affect them adversely as class, and
are not entitled to receive dividends. The carrying value of the redeemable preferred stock was $7.11 per share at December 31,
2014 and 2013.

The redeemable preferred stock is required to be shown in the Company’s financial statements separate from

stockholders’ equity and any adjustments to its carrying value to its redemption value up to its redemption value of $9.00 per
share will be reported as a dividend.

F-27

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Eclipse Advisors, LLC

On May 8, 2012, the Company entered into an equity line of credit arrangement with Eclipse Advisors, LLC (“Eclipse”),
which provides that, upon the terms and subject to the conditions set forth therein, the Company is entitled to sell and Eclipse is
committed to purchase up to $25 million of shares of the Company’s common stock over a 24-month term, which expired on
May 8, 2014 (the “Investment Agreement). From time to time, and at the Company’s sole discretion, the Company may present
Eclipse with put notices, to purchase the Company’s common stock in two tranches over a 31-day period (a “put period”) with
each put period subject to being reduced by the Company based on a minimum threshold price of the Company’s common
stock during the put period. The Company may not present Eclipse with a new put notice at any time there is an outstanding put
notice.

Once presented with a put notice, Eclipse is required to purchase: (i) 50% of the dollar amount of the shares specified in

the put notice on the 16th day after the date of the put notice; and (ii) 50% of the dollar amount of the shares specified in the put
notice on the 31st day after the date of the put notice. The price per share for the sale of such common stock for each of the two
closings in a put period shall be 90% of the volume weighted average price for the Company’s common stock over the trading
days that exist during the 15 days prior to such closing date. If the daily volume weighted average price of the Company’s
common stock falls below a threshold price established by the Company on any trading day during a put period, the Company
has the right to send a cancellation notice to Eclipse, which will reduce the Company’s obligation to sell the shares to Eclipse to
no greater than 50% of the dollar amount set forth in the put notice.

Upon execution of the Investment Agreement and as provided for therein, the Company issued Eclipse 231,045 shares of

common stock representing a $500,000 commitment fee, determined by dividing $500,000 by the volume weighted average
price for the Company’s common stock for the five trading days preceding the effective date of the Investment Agreement. The
Company has not sold any shares to Eclipse under the Investment Agreement.

9. Equity Transactions

Warrants

In connection with the execution of the Facility Agreement, on March 17, 2014, the Company issued to Deerfield the

Initial Warrants to purchase an aggregate of 6,250,000 shares of the Company’s common stock immediately exercisable at an
exercise price equal to $1.39 expiring on March 17, 2020. The number of shares of common stock into which the Initial
Warrants are exercisable and the exercise price will be adjusted to reflect any stock splits, payment of stock dividends,
recapitalizations, reclassifications or other similar adjustments in the number of outstanding shares of the Company’s common
stock. The warrants have the same dividend rights to the same extent as if the warrants had been exercised for shares of
common stock.

The Company agreed that upon each disbursement borrowing under the Facility Agreement, the Company would issue to
Deerfield Draw Warrants to purchase up to an aggregate of 10,000,000 shares of the Company’s common stock, at an exercise
price equal to the lesser of the Initial Warrant exercise price or the average daily volume weighted average price per share of the
Company’s common stock for the 15 days following the request for borrowing. The number of Draw Warrants issued for each
draw will be in proportion to the amount of draw compared to the total $50 million facility.

The Initial Warrants were valued on March 17, 2014 using a Black-Scholes option pricing model that resulted in a value

of $5.7 million, which was recorded as a current liability with an offset to a deferred charge asset and will be amortized on a
straight line basis through interest expense over the term of the Facility Agreement commitment period ended January 30, 2015.
To the extent the Company draws on the $50 million Facility Agreement, a proportionate amount of the unamortized current
deferred charge will be reclassified as debt discount and amortized through interest expense over the term of the debt using the
effective interest method.

On March 20, 2014, the Company made an initial draw of $20 million under the Facility Agreement and received net

proceeds of $19.5 million to fund the portion of the Orthotec settlement payment obligations that were due in 2014. In
connection with this borrowing, the Company issued Draw Warrants to purchase 4,000,000 shares of common stock at an
exercise price of $1.39. The Draw Warrants were valued at $4.7 million using the Black-Scholes option pricing model, which
was recorded as a current liability with an offset to debt discount.

On November 21, 2014, the Company made a second draw of $6 million under the Facility Agreement and received net

proceeds of $5.9 million to fund the portion of the Orthotec settlement payments payable through 2016. The $0.2 million
transaction fee was recorded as a debt discount and is being amortized over the remaining term of the draw, which ends March
20, 2019. In connection with this borrowing, the Company issued Draw Warrants to purchase 1,200,000 shares of common

F-28

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

stock at an exercise price of $1.39, which were valued at $0.9 million and recorded as a debt discount and is being amortized
over the term of the draw.

As of December 31, 2014, the outstanding Initial Warrants and Draw Warrants to purchase an aggregate of 11,450,000
shares of common stock outstanding were revalued to their fair value with a gain recorded to to other income (expense) of $2.6
million for the year ended December 31, 2014. The warrant liability of $8.7 million is recorded as common stock warrant
liabilities within current liabilities on the condensed consolidated balance sheet as of December 31, 2014.

At December 31, 2014, the Company's outstanding warrants were valued using the Black-Scholes option pricing model.

This is a Level 3 measurement using the following assumptions:

Risk-free interest rate

Dividend yield

Expected volatility

Expected life (years)

December 31, 2014

1.8%

—%

61%

5.3

10. Stock Benefit Plans and Stock-Based Compensation

In 2005, the Company adopted its 2005 Employee, Director, and Consultant Stock Plan (the “2005 Plan”). The 2005 Plan

allows for the grant of options, restricted stock and restricted stock unit awards to employees, directors, and consultants of the
Company. The 2005 Plan has 15,800,000 shares of common stock reserved for issuance. The Board of Directors determines the
terms of the restricted stock, the terms of the restricted stock units, and the terms of the stock options, including the number of
shares for which each option is granted, the exercise price, vesting schedule, expiration date, and whether restrictions will be
imposed on the shares subject to options. Options granted under the 2005 Plan expire no later than 10 years from the date of
grant (5 years for incentive stock options granted to holders of more than 10% of the Company’s voting stock). Options
generally vest over a four year period and may be immediately exercisable upon a change of control of the Company. The
exercise price of incentive stock options may not be less than 100% of the fair value of the Company’s common stock on the
date of grant. The exercise price of any option granted to a 10% stockholder may be no less than 110% of the fair value of the
Company’s common stock on the date of grant. At December 31, 2014, approximately 3.4 million shares of common stock
remained available for issuance under the 2005 Plan.

On July 30, 2014, the Company amended the 2005 Plan (the “Plan Amendment”) to authorize the granting of time-based

and performance-based restricted stock units, which represent a contingent entitlement to receive shares of the Company’s
common stock, to employees, directors and consultants of the Company under the Plan. Prior to the Plan Amendment, the Plan
provided solely for the granting of stock options and restricted stock.

Stock Options

A summary of the Company’s stock option activity under the 2005 Plan and related information is as follows (in

thousands, except as indicated and per share data):

Outstanding at December 31, 2013

Granted

Exercised
Forfeited

Outstanding at December 31, 2014

Options vested and exercisable at December 31, 2014

Options vested and expected to vest at December 31, 2014

F-29

Weighted
average
exercise
price

7,761

2,019

$
(21) $
(1,492) $
$
8,267

4,149
7,819

$
$

2.23

1.42
1.33
1.99

2.08

2.46
2.11

Weighted
average
remaining
contractual
term
(in years)

Aggregate
intrinsic
value

7.59

753

—
—
—

7.35

6.16
7.26

$
$

—
—
—

27
64

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

The weighted-average grant-date fair value per share of stock options granted during the years ended December 31, 2014,

2013 and 2012 was $0.81, $1.09 and $1.10, respectively. The aggregate intrinsic value of options at December 31, 2014 is
based on the Company’s closing stock price on that date of $1.41 per share.

As of December 31, 2014, there was $7.5 million of unrecognized compensation expense for stock options and awards

which is expected to be recognized on a straight-line basis over a weighted average period of approximately 2.5 years. The total
intrinsic value of options exercised was immaterial for the years ended December 31, 2014, 2013 and 2012.

Restricted Stock Awards

The following table summarizes information about the restricted stock awards activity (in thousands, except as indicated

and per share data):

Unvested at December 31, 2013

Awarded
Vested
Forfeited

Unvested at December 31, 2014

Weighted
average
grant
date fair
value

Weighted
average
remaining
recognition
period
(in years)

1.88
1.32
2.25
1.57
1.60

2.30

1.83

$
807
493
$
(155) $
(455) $
$
690

The weighted average fair value per share of awards granted during the years ended December 31, 2014, 2013 and 2012

was $1.32, $1.97 and $1.57, respectively.

Performance Based Restricted Stock Units

In July 2014, the Company granted 932,000 performance-based restricted stock units ("PSUs") to certain employees
under its 2005 Plan. The PSUs vest based upon the Company's achievement of certain performance goals over the period from
July 1, 2014 through December 31, 2016. The number of PSUs that may vest varies between 0%-200% based on the
achievement of such goals. The PSUs were valued at $1.42 per share based on the closing price of the Company's common
stock on the date of grant. For purposes of measuring compensation expense, the amount of PSUs ultimately expected to vest is
estimated at each reporting date based on management’s expectations regarding the relevant performance criteria. The
recognition of compensation expense associated with PSUs requires judgment in assessing the probability of meeting the
performance goals, as well as defined criteria for assessing achievement of the performance-related goals.

Unvested at December 31, 2013

Awarded

Vested

Forfeited

Unvested at December 31, 2014

Weighted
average
grant
date fair
value

Weighted
average
remaining
recognition
period
(in years)

—

1.42

—

1.42

0.00

2.00

— $

932

— $
(78) $
$
854

F-30

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Warrants

In March 2012, the Company entered into a consulting agreement with a third-party entity pursuant to which the
Company issued a warrant to the consultant to purchase an aggregate of 500,000 shares of the Company’s common stock at an
exercise price of $2.50 per share. The warrant expires on March 1, 2015.

In December 2011, in connection with the third amendment to the SVB Credit Facility, finance charges totaling $0.2
million were waived in exchange for the issuance to SVB of warrants to purchase 93,750 shares of the Company’s common
stock. The warrants are immediately exercisable, can be exercised through a cashless exercise, have an exercise price of $1.60
per share and have a ten year term.

Elite Medical Holdings and Pac 3 Surgical Collaboration Agreement

In October 2013, the Company entered into a three-year collaboration agreement with a third party to provide consultation

services to assist the Company in the development of its products and its products in development. Under the terms of the
collaboration agreement, the Company will gain exclusive rights to the use of all intellectual property developed by the
collaborators. The Company will make three annual payments to the collaborator as sole consideration for services provided,
totaling an aggregate of up to $8 million, paid in common stock of Alphatec Holdings at a per share price of $1.95, which was
equal to the average NASDAQ closing price of the common stock on the five days leading up to and including the date of
signing the collaboration agreement. The actual number of shares issued each year will be determined by the fair market value
of the services provided over the prior 12 months. As of December 31, 2014, the Company has issued 1,456,035 shares of its
common stock under this agreement and recorded expense of $1.9 million and $0.5 million in the years ended December 31,
2014 and 2013, respectively.

Media Advertising Agreement

In 2012, the Company entered into consulting agreements with a third-party entity for marketing and advertising services.

In connection with these agreements, the Company paid the consultant $0.2 million, issued 500,000 registered shares of the
Company’s common stock and issued 352,000 unregistered shares of the Company’s common stock. In May 2013, the
Company entered into an additional consulting agreement with this third-party entity for marketing and advertising services. In
connection with this additional agreement, the Company paid the consultant total cash consideration of $0.2 million and issued
225,000 restricted shares of the Company’s common stock. The Company recorded total stock compensation related to these
agreements of less than $0.1 million during the year ended December 31, 2014 and $0.7 million and $1.1 million, respectively,
during the years ended December 31, 2013 and 2012.

Common Stock Reserved for Future Issuance

Common stock reserved for future issuance consists of the following (in thousands):

Stock options outstanding
Awards outstanding
Performance restricted stock units outstanding
Warrants outstanding
Authorized for future grant under 2005 Plan

December 31, 2014

8,267
690
854
12,044
3,408

25,263

F-31

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

11. Income Taxes

The components of the pretax loss from operations for the years ended December 31, 2014, 2013 and 2012 are as follows

(in thousands):

U.S. Domestic
Foreign

Pretax loss from operations

Year Ended December 31,

2014

2013

2012

(8,106) $
(3,689)
(11,795) $

(9,264) $
(69,784)
(79,048) $

(3,310)
(13,308)
(16,618)

The components of the provision (benefit) for income taxes are presented in the following table (in thousands):

Current:

Federal
State
Foreign
Total current provision (benefit)

Deferred:

Federal
State
Foreign
Total deferred provision (benefit)
Total provision (benefit)

Year Ended December 31,

2014

2013

2012

— $
145
526
671

238
24
154
416
1,087

(21) $
186
2,525
2,690

229
15
245
489
3,179

107
24
2,083
2,214

137
29
(3,539)
(3,373)
(1,159)

The provision (benefit) for income taxes differs from the amount of income tax determined by applying the applicable

U.S. statutory federal income tax rate to pretax income as a result of the following differences:

Federal statutory rate
Adjustments for tax effects of:

State taxes, net
Stock-based compensation
Foreign taxes
Tax credits
Deemed foreign dividend
Fair market value adjustments
Intercompany debt forgiveness and other permanent adjustments
Tax rate adjustment
Uncertain tax positions
Other
Valuation allowance

Effective income tax rate

2014

December 31,

2013

2012

(35.0)%

(1.1)%
6.2 %
3.4 %
(3.3)%
— %
(7.6)%
3.1 %
0.4 %
5.3 %
0.2 %
37.5 %
9.1 %

(0.1)%
0.5 %
1.1 %
(0.4)%
— %
— %
9.5 %
0.2 %
2.7 %
(0.4)%
25.9 %
4.0 %

— %
(0.5)%
(0.1)%
(0.7)%
0.2 %
— %
5.0 %
0.7 %
14.9 %
3.3 %
5.2 %
(7.0)%

The 2014 provision for income taxes primarily consists of an increase in unrecognized tax benefits associated with the

European operations, tax expense related to non-income based state tax in the U.S. and current year income in Japan and Brazil,
and an increase in the deferred tax liability related to tax-deductible goodwill in the U.S.

F-32

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

Significant components of the Company’s deferred tax assets and liabilities as of December 31, 2014 and 2013 are as

follows (in thousands):

Deferred tax assets:

Allowances and reserves
Accrued expenses
Inventory reserves
Net operating loss carryforwards
Property and equipment
Stock-based compensation
Legal settlement
Income tax credit carryforwards
Total deferred tax assets

Valuation allowance

Total deferred tax assets, net of valuation allowance

Deferred tax liabilities:

Property and equipment
Intangible assets
Goodwill
Total deferred tax liabilities
Net deferred tax assets (liabilities)

December 31,

2014

2013

818
3,674
8,532
41,965
1,976
2,168
1,204
2,218
62,555
(58,781)
3,774

—
2,881
1,518
4,399
(625) $

816
3,685
7,549
26,497
1,171
2,769
17,998
1,800
62,285
(56,690)
5,595

—
4,806
1,256
6,062
(467)

The realization of deferred tax assets may be dependent on the Company’s ability to generate sufficient income in future
years in the associated jurisdiction to which the deferred tax assets relate. As of December 31, 2014, a valuation allowance of
$58.8 million has been established against the net deferred tax assets as realization is uncertain. The net deferred tax assets
primarily consist of Japanese deferred tax assets. The deferred tax liabilities consist of tax-deductible goodwill in the U.S.
Deferred tax liabilities associated with tax-deductible goodwill cannot be considered a source of income to support the
realization of deferred tax assets because the reversal of these deferred tax liabilities is considered indefinite. At December 31,
2014, such amounts represent $1.5 million.

In determining the need for a valuation allowance the Company considers all available positive and negative evidence,

including scheduled reversals of deferred tax liabilities, projected future taxable income, tax planning strategies, and recent
financial performance. Based on the review of all positive and negative evidence, including a three year cumulative pre-tax
loss, the Company determined that a full valuation allowance should be recorded against all U.S. and European deferred tax
assets at December 31, 2014. During 2012, it was determined that the Company was more-likely-than-not to realize its Japanese
deferred tax assets. The Company removed the valuation allowance on the Japanese deferred tax assets and recognized a tax
benefit of $1.4 million in 2012. In the event that the Company determines that it would not be able to realize all or part of its
Japanese deferred tax assets in the future, it would increase the valuation allowance and recognize a corresponding tax
provision in the period in which it made such a determination. Likewise, if the Company later determines that it is more-likely-
than-not to realize all or a portion of the U.S. or European deferred tax assets, it would reverse the previously provided
valuation allowance.

At December 31, 2014, the Company has unrecognized tax benefits of $8.9 million of which $8.1 million will affect the

effective tax rate if recognized when the Company no longer has a valuation allowance offsetting its deferred tax assets.

F-33

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

The following table summarizes the changes to unrecognized tax benefits for the years ended December 31, 2014, 2013

and 2012 (in thousands):

Balance at December 31, 2011

Additions based on tax positions related to the prior year
Additions based on tax positions related to the current year
Reductions as a result of lapse of applicable statute of limitations
Additions as a result of foreign exchange rates and other

Balance at December 31, 2012

Balance at December 31, 2013

Additions based on tax positions related to the prior year
Additions based on tax positions related to the current year
Reductions as a result of lapse of applicable statute of limitations
Reductions as a result of foreign exchange rates and other

Balance at December 31, 2014

4,197
987
743
(58)
28

5,897
221
1,664
(20)
73

7,835
391
1,050
(40)
(375)

8,861

The Company believes it is reasonably possible it will not materially reduce its unrecognized tax benefits within the next

12 months.

The Company and its subsidiaries are subject to federal income tax as well as income tax of multiple state and foreign
jurisdictions. With few exceptions, the Company is no longer subject to income tax examination by tax authorities in major
jurisdictions for years prior to 2009. However, to the extent allowed by law, the taxing authorities may have the right to
examine prior periods where net operating losses and tax credits were generated and carried forward, and make adjustments up
to the amount of the carryforwards. The Company is not currently under examination by the Internal Revenue Service, foreign
or state and local tax authorities.

The Company recognizes interest and penalties related to uncertain tax positions as a component of the income tax
provision. As of December 31, 2014, accrued interest and penalties were $1.3 million, which primarily relates to the uncertain
tax positions of the Scient’x operations. During 2014, there was an increase of $0.2 million in the accrued interest and penalties
related to the uncertain tax positions of the Scient’x operations.

At December 31, 2014, the Company had federal and state net operating loss carryforwards of $45.5 million and $56.6

million, respectively, expiring at various dates through 2034. At December 31, 2014, the Company had federal and state
research and development tax credits of $3.1 million and $2.8 million, respectively. The federal research and development tax
credits expire at various dates through 2034, while the state credits do not expire. The Company had foreign net operating loss
carryforwards of $84.6 million beginning to expire in 2018. Utilization of the net operating loss and tax credit carryforwards
may become subject to annual limitations due to ownership change limitations that could occur in the future as provided by
Section 382 of the Internal Revenue Code of 1986, as amended, as well as similar state and foreign provisions. These
ownership changes may limit the amount of the net operating loss and tax credit carryforwards that can be utilized annually to
offset future taxable income. An ownership change occurred during June 2006 in connection with the initial public offering.
The annual limitation as a result of that ownership change did not result in the loss or substantial limitation of net operating loss
or tax credit carryforwards. There have been no subsequent ownership changes through December 31, 2014.

The Company does not record U.S. income taxes on the undistributed earnings of its foreign subsidiaries based upon the
Company’s intention to permanently reinvest undistributed earnings to ensure sufficient working capital and further expansion
of existing operations outside the United States. The undistributed earnings of the foreign subsidiaries as of December 31, 2014
are immaterial. In the event the Company is required to repatriate funds from outside of the United States, such repatriation
would be subject to local laws, customs, and tax consequences.

F-34

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

12. Segment and Geographical Information

Operating segments are defined as components of an enterprise for which separate financial information is available and
evaluated regularly by the chief operating decision maker, or decision-making group, in deciding how to allocate resources and
in assessing performance. The Company operates in one reportable business segment.

During the years ended December 31, 2014, 2013 and 2012, the Company operated in two geographic regions, the U.S.

and International regions. The International region consists of locations outside of the U.S. In the International geographic
location, sales in Japan for the years ended December 31, 2014, 2013 and 2012 totaled $31.9 million, $28.0 million and $28.6
million, respectively, which represented greater than 10 percent of the Company’s consolidated revenues for the years then
ended December. For the years ended December 31, 2014, 2013 and 2012, sales in other individual countries included in the
International region did not exceed 10 percent of consolidated revenues.

Revenues attributed to the geographic location of the customer were as follows (in thousands):

United States
International
Total consolidated revenues

Total assets by geographic region were as follows (in thousands):

United States
International
Total consolidated assets

13. Related Party Transactions

Year Ended December 31,

2014

2013

2012

137,060
69,920
206,980

134,951
69,773
204,724

130,476
65,802
196,278

December 31,

2014

2013

200,978
143,945
344,923

196,383
169,247
365,630

For the years ended December 31, 2014, 2013 and 2012, the Company incurred costs of $0.2 million, $0.2 million and

$0.2 million, respectively, to Foster Management Company and HealthpointCapital, LLC for travel and administrative
expenses. John H. Foster is a significant equity holder of HealthpointCapital, LLC, an affiliate of HealthpointCapital Partners,
L.P. and HealthpointCapital Partners II, L.P., which are the Company’s principal stockholders.

Indemnification Agreements

The Company has entered into indemnification agreements with certain of its directors, which are named defendants in
the Orthotec litigation matter in New York (See Note 7 - Commitments and Contingencies - Litigation). The indemnification
agreements require the Company to indemnify these individuals to the fullest extent permitted by applicable law and to advance
expenses incurred by them in connection with any proceeding against them with respect to which they may be entitled to
indemnification by the Company. For the years ended December 31, 2014 and 2013, the Company paid less than $0.1 million
and $1.7 million, respectively, in connection with the indemnification obligations of Scient’x and Surgiview, all of which was
related to the Orthotec matter. (See Note 7).

14. Retirement Plan

The Company maintains an employee savings plan that qualifies as a deferred salary arrangement under Section 401(k) of

the Internal Revenue Code. Under the savings plan, participating employees may contribute a portion of their pre-tax earnings,
up to the Internal Revenue Service annual contribution limit. Additionally, the Company may elect to make matching
contributions into the savings plan at its sole discretion of up to 4% of each individual’s compensation. Matching contributions
vest after one year of service. The Company’s total contributions to the 401(k) plan were $0.6 million, $0.6 million and $0.5
million for the years ended December 31, 2014, 2013 and 2012, respectively.

F-35

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

15. Restructuring Activities

On September 16, 2013, the Company announced that Scient'x began a process to significantly restructure its business
operations in France in an effort to improve operating efficiencies and rationalize its cost structure. The restructuring included a
reduction in Scient'x's workforce and closing of the manufacturing facilities in France. The Company has recorded total costs of
$10.4 million through December 31, 2014 associated with this restructuring, which includes employee severance, social plan
benefits and related taxes, facility closing costs, manufacturing transfer costs, and contract termination costs. In accordance
with ASC Topic 420, Accounting for Costs Associated with Exit or Disposal Activities, and ASC Topic 712, Non retirement
Postemployment Benefits, the Company recorded a restructuring charge accrual in accrued expenses of $0.5 million and $9.2
million within the consolidated balance sheets as of December 31, 2014 and 2013, respectively. Additionally, the Company has
recorded restructuring expenses of $0.7 million within the consolidated statements of operations for the year ended
December 31, 2014. The Company has substantially completed the activities associated with the restructuring as of
December 31, 2014, and a substantial portion has been paid.

In connection with the restructuring plan, the Company modified its estimate of inventory and instrument net book value
at its Scient'x entities based on revised global demand. The Company recorded an additional inventory reserve of $4.9 million
in the year ended December 31, 2013 which is included in cost of goods sold within the consolidated statements of operations.

Below is a table of the movement (in thousands):

Accrued Balance at

Expensed

Paid and

Accrued Balance at

Total Costs

Social plan costs

December 31, 2013
9,170
$

December 31, 2014
197
$

Other restructuring costs

—

Total

9,170

509

706

Other

(8,836) $
(509)
(9,345) $

December 31, 2014
531

Incurred

9,450

921

10,371

—

531

16. Cross Medical

On February 12, 2010, a complaint was filed in the U.S. District Court for the Central District of California, by Cross

Medical Products, LLC, or Cross, (a subsidiary of Biomet), Cross Medical Products, LLC v. Alphatec Spine, Inc., Case
No. 8:10-cv-176-MRP -MLG, alleging that we breached a patent license agreement with Cross by failing to make certain
royalty payments allegedly due under the agreement. Cross was seeking payment of prior royalties allegedly due from the
Company’s sales of polyaxial screws and an order from the court regarding payment of future royalties by us. In its complaint,
Cross alleged a material amount of damages were due to it as a result of our alleged breach of the patent license agreement.

In January 2011, we filed a complaint in the U.S. District Court for the Southern District of California against Biomet,

Inc., or Biomet, alleging that Biomet’s TPS-TL products infringe one of our patents. On December 30, 2011, we reached a
global settlement agreement of the pending lawsuits with Biomet and Cross. Under the terms of the settlement, all parties
obtained a release of all claims that were the subject of the disputes. No party has admitted liability in connection with the
settlement. The settlement also includes an amendment to the April 23, 2003 License Agreement.

As part of the settlement, we agreed to pay Cross an initial payment of $5 million, which payment was made in January
2012. In addition to the initial payment, we agreed to make thirteen quarterly payments of $1 million beginning on August 1,
2012, with each subsequent payment due three months thereafter until the final payment is made in August 2015. The
remaining cash obligations totaling $3 million as of December 31, 2014, will be paid in 2015. In addition, pursuant to the
settlement, the parties have exchanged covenants not to sue for patent infringement with respect to products that each respective
company had on the market as of December 30, 2011.

F-36

ALPHATEC HOLDINGS, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS—(Continued)

17. Quarterly Financial Data (Unaudited)

The following financial information reflects all normal recurring adjustments, which are, in the opinion of management,

necessary for a fair statement of the results of the interim periods. Summarized quarterly data for fiscal 2014 and 2013 are as
follows (in thousands, except per share data):

Selected quarterly financial data:
Revenue
Gross profit
Total operating expenses
Net loss
Net loss per basic share (1)
Net loss per diluted share (1)

Selected quarterly financial data:
Revenue
Gross profit
Total operating expenses
Net loss
Net loss per basic and diluted share (1)

1st
Quarter

Year ended December 31, 2014

2nd
Quarter

3rd
Quarter

4th
Quarter

49,173
33,294
37,996
(6,673)
(0.07)
(0.07)

1st
Quarter

50,443
32,742
34,100
(2,649)
(0.03)

53,167
36,120
34,279
(2,895)
(0.03)
(0.03)

51,013
36,306
34,574
(3,041)
(0.03)
(0.04)

Year ended December 31, 2013

2nd
Quarter

3rd
Quarter

51,020
32,093
34,992
(4,661)
(0.05)

50,196
24,232
37,406
(14,510)
(0.15)

53,627
37,690
34,717
(273)
0.00
(0.03)

4th
Quarter

53,065
35,255
91,257
(60,407)
(0.62)

(1) Basic and diluted net loss per share is computed independently for each of the quarters presented. Therefore, the sum of

the quarterly per share amounts will not necessarily equal the total for the year.

F-37

SCHEDULE II—VALUATION AND QUALIFYING ACCOUNTS

Allowance
for
Doubtful
Accounts (1)

Reserve for
Excess and
Obsolete
Inventories (2)

(In thousands)
1,055
859
(840)
1,074
404
(430)
1,048
522
(777)
793

13,174
6,658
(2,610)
17,222
11,652
(4,928)
23,946
3,539
(6,160)
21,325

Balance at December 31, 2011

Provision
Write-offs and recoveries, net

Balance at December 31, 2012

Provision
Write-offs and recoveries, net

Balance at December 31, 2013

Provision
Write-offs and recoveries, net

Balance at December 31, 2014

(1) The provision is included in selling expenses.
(2) The provision is included in cost of revenues.

F-38

COMPARISON OF 5 YEAR CUMULATIVE TOTAL RETURN*
Among Alphatec Holdings, Inc, the NASDAQ Composite Index,
and the NASDAQ Medical Equipment Index

$250

$200

$150

$100

$50

12/09

12/10

12/11

12/12

12/13

12/14

Alphatec Holdings, Inc

NASDAQ Composite

NASDAQ Medical Equipment

*$100 invested on 12/31/09 in stock or index, including reinvestment of dividends.
Fiscal year ending December 31.

Corporate Information

Notice of Annual Meeting

Thursday, June 25, 2015 - 2:00 pm PT
Alphatec Holdings, Inc. Corporate Headquarters
5818 El Camino Real Carlsbad, CA 92008

Stock Symbol

Annual Report on Form 10-K

The common stock of Alphatec Holdings, Inc. is traded on the
NASDAQ Global Select Market under the ticker symbol “ATEC”.

Stockholder Information

Investor Relations
Alphatec Spine, Inc.
5818 El Camino Real
Carlsbad, CA 92008
Telephone: 760.494.6610
Fax: 760.930.2513
Email: investorrelations@alphatecspine.com

Stock Transfer Agent

Computershare, Inc.
480 Washington Blvd.
Jersey City, NJ 07310
Shareholder Communication Center:
800.356.2017
www.computershare.com

Securities Counsel

Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
One Financial Center
Boston, MA 02111
www.mintz.com

Independent Registered Public Accounting Firm

Ernst & Young LLP
4370 La Jolla Village Drive
Suite 500
San Diego, CA 92122
www.ey.com

A copy of Alphatec Holdings annual report to the U.S. Securities and
Exchange Commission on Form 10-K is available without charge online
at www.alphatecspine.com or upon written request to the Investor
Relations Department (listed at left).

Forward Looking Statements

We caution you that statements included in this annual report that are not a description of historical
facts are forward-looking statements that involve risks, uncertainties, assumptions and other
factors which, if they do not materialize or prove correct, could cause our results to differ materially
from historical results or those expressed or implied by such forward-looking statements. Forward
looking statements include references to Alphatec Spine’s 2015 business prospects; estimates
of market sizes and future growth of those markets, new product development cycle and market
success of those new products; improvements to the Company’s operations and reductions in
the Company’s manufacturing costs and operating expenses, including our estimates for market
sizes and our ability to penetrate such markets. The important factors that could cause actual
operating results to differ significantly from those expressed or implied by such forward-looking
statements include, but are not limited to; the uncertainty of success in developing new products
or products currently in Alphatec Spine’s pipeline; the successful global launch of the Company’s
new products and the products in its development pipeline; failure to achieve acceptance of
Alphatec Spine’s products by the surgeon community including products discussed in this annual
report; timing of U.S. FDA or other foreign and domestic governmental agency decisions that
impact commercialization and distribution of the Company’s products; Alphatec Spine’s ability to
develop and expand its U.S. and/or global revenues; continuation of favorable third party payor
reimbursement for procedures performed using Alphatec Spine’s products; pricing impacts on
the spine market; unanticipated expenses or liabilities or other adverse events affecting cash flow
or Alphatec Spine’s ability to successfully control its costs or achieve profitability and the potential
need to raise additional funding; maintain an adequate sales network for our products, including
the ability to attract and retain independent distributors; enhance our U.S. and international
sales networks and increase product penetration; attract and retain a qualified management
team, as well as other qualified personnel and advisors; the ability to enter into licensing and
acquisition agreements with third parties and to successfully integrate the acquired technology
and/or businesses; our management team’s ability to accommodate growth and manage a larger
organization; uncertainty of additional funding; Alphatec Spine’s ability to compete with other
competing products and with emerging new technologies; product liability exposure; our ability to
meet our financial obligations set forth in the MidCap credit facility, the Deerfield credit facility and
each of the Cross Medical and OrthoTec settlement agreements; patent infringement claims and
claims related to Alphatec Spine’s intellectual property. Please refer to the risks detailed in Alphatec
Spine’s SEC reports, including the attached Annual Report on Form 10-K and in our periodic filings
including quarterly reports on Form 10-Q and reports on Form 8-K. Our public filings with the
Securities and Exchange Commission are available at www.sec.gov and on our website at www.
alphatecspine.com. We do not intend to update any forward-looking statement to reflect events or
circumstances arising after the date on which it was made.

Alphatec, Alphatec Spine, the Alphatec logo, Alphatec Solus, Alphagraft, AmnioShield, Arsenal,
Aspida, Avalon, Bone’x, Bridgepoint, Discocerv, Epicage, Helifix, Illico, Isobar, Leucadia, Nexoss,
Novel, PCB Evolution, Pegasus, Profuse, OsseoFix, OsseoScrew, 3D Profuse, Samarys, Solanas,
TeCorp, Trestle, Trestle Luxe, Velossity, Xenon, and Zodiac are trademarks or registered trademarks
of Alphatec Spine, Inc., or its affiliates. © 2015 Alphatec Spine, Inc. All rights reserved. The
Alphatec Solus product is not sponsored, endorsed by, or in any way affiliated with SOLAS® or The
Society of Lateral Access Surgery.

Executive Team
(cid:2)(cid:3) James M. Corbett

Board of Directors
(cid:2)(cid:3) Leslie H. Cross

President and Chief Executive Officer

Chairman of the Board of Directors

(cid:2)(cid:3) Michael O’Neill

(cid:2)(cid:3) James M. Corbett

Chief Financial Officer and Treasurer

President and Chief Executive Officer, Alphatec Spine, Inc.

(cid:2)(cid:3) Michael J. Plunkett
Chief Operating Officer

(cid:2)(cid:3) Mitsuo Asai

(cid:2)(cid:3) Mortimer Berkowitz III

President and Managing Director, HealthpointCapital, LLC

(cid:2)(cid:3) Tom C. Davis

President, Alphatec Pacific, Inc.

Chief Executive Officer of The Concorde Group

(cid:2)(cid:3) Ebun S. Garner, Esq.

General Counsel, Senior Vice President and Secretary

(cid:2)(cid:3) Rohit M. Desai

Founder, Chairman and President,
Desai Capital Management Incorporated

(cid:2)(cid:3) Kristin Machacek Leary

Senior Vice President, Human Resources

(cid:2)(cid:3) Mark Bullivant

Senior Vice President, International

(cid:2)(cid:3) John H. Foster

Chairman and Managing Director, HealthpointCapital, LLC

(cid:2)(cid:3) James R. Glynn

Former President, CFO and Director, Invitrogen Corp.

(cid:2)(cid:3) Siri S. Marshall

Former General Counsel, General Mills, Inc.

(cid:2)(cid:3) R. Ian Molson

Former Deputy Chairman of the Board, Molson, Inc.

(cid:2)(cid:3) Stephen E. O’Neil

Founder and Principal, The O’Neil Group

(cid:2)(cid:3) Donald A. Williams

Former Partner, Grant Thornton, LLP

CORPORATE HEADQUARTERS
5818 El Camino Real
Carlsbad, California 92008

CUSTOMER SERVICE
Toll Free: 800.922.1356
Local: 760.431.9286
Fax: 800.431.1624