Quarterlytics / Healthcare / Medical - Diagnostics & Research / Applied DNA Sciences

Applied DNA Sciences

apdn · NASDAQ Healthcare
Claim this profile
Ticker apdn
Exchange NASDAQ
Sector Healthcare
Industry Medical - Diagnostics & Research
Employees 51-200
← All annual reports
FY2018 Annual Report · Applied DNA Sciences
Sign in to download
Loading PDF…
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 10-K

xx ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the fiscal year ended September 30, 2018

¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from _____ to _____

Commission File Number 001-36745

APPLIED DNA SCIENCES, INC.
(Exact name of registrant as specified in its charter)

Delaware
(State or other jurisdiction of
incorporation or organization)

59-2262718
(I.R.S. Employer
Identification No.)

50 Health Sciences Drive,
Stony Brook, New York
(Address of principal executive offices)

11790
(Zip Code)

Securities registered under Section 12(b) of the Act:

Title of Each Class
Common Stock, $0.001 par value
Warrants to purchase Common Stock

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act.

Securities registered under Section 12(g) of the Act: None

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act.

(631) 840-8800
(Registrant’s telephone number,
including area code)

Name of each Exchange
on Which Registered
The NASDAQ Capital Market
The NASDAQ Capital Market

¨     Yes     x     No

¨     Yes     x     No

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12
months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.

x     Yes     ¨     No

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§ 232.405 of
this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).

x     Yes     ¨     No

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of registrant’s
knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K. ¨

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company.
See the definitions of “large accelerated filer,” “accelerated filer”, “smaller reporting company”, and “emerging growth company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer ¨

Accelerated filer ¨

Non-accelerated filer x

Smaller reporting company x

Emerging growth company ¨

If an emerging growth company, indicate by a check mark if the registrant has elected to not use the extended transition period of complying with any new or revised financial
accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act). ¨   Yes      x   No

The aggregate market value of the Registrant’s voting and non-voting common stock held by non-affiliates of the Registrant, based upon the last sale price of the common stock
reported on The Nasdaq Capital Market as of the last business day of the Registrant’s most recently completed second fiscal quarter (March 31, 2018), was approximately $38
million. Shares of the Registrant’s common stock held by each executive officer and director and by each entity or person that, to the Registrant’s knowledge, owned 5% or more of
the Registrant’s outstanding common stock as of March 31, 2018 have been excluded in that such persons may be deemed to be affiliates of the Registrant. This determination of
affiliate status is not necessarily a conclusive determination for other purposes.

As of December 14, 2018, the Registrant had outstanding 30,112,057 shares of common stock, par value $0.001 per share.

DOCUMENTS INCORPORATED BY REFERENCE
Portions of the Registrant’s definitive Proxy Statement for the 2019 Annual Meeting of Shareholders, to be filed within 120 days after the end of the fiscal year ended September 30,
2018 and incorporated by reference in Part III hereof. Except with respect to information specifically incorporated by reference in the Annual Report on Form 10-K, the Proxy
Statement is not deemed to be filed as part hereof.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TABLE OF CONTENTS

BUSINESS
RISK FACTORS
UNRESOLVED STAFF COMMENTS
PROPERTIES
LEGAL PROCEEDINGS
MINE SAFETY DISCLOSURES

MARKET FOR COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND ISSUER PURCHASES OF EQUITY SECURITIES
SELECTED FINANCIAL DATA
MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS
QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK
FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA
CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL DISCLOSURE
CONTROLS AND PROCEDURES
OTHER INFORMATION

DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE
EXECUTIVE COMPENSATION
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS
CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE
PRINCIPAL ACCOUNTING FEES AND SERVICES

PART I

ITEM 1.
ITEM 1A.
ITEM 1B.
ITEM 2.
ITEM 3.
ITEM 4.

PART II

ITEM 5.
ITEM 6.
ITEM 7.
ITEM 7A.
ITEM 8.
ITEM 9.
ITEM 9A.
ITEM 9B.

PART III

ITEM 10.
ITEM 11.
ITEM 12.
ITEM 13.
ITEM 14.

PART IV

ITEM 15.

EXHIBITS AND FINANCIAL STATEMENT SCHEDULES

I

Page

2
26
42
42
42
42

43
43
43
51
51
51
51
51

52
52
52
52
52

52

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Forward-looking Information

PART I

This Annual Report on Form 10-K (including but not limited to Item 7, “Management’s Discussion and Analysis of Financial Condition and Results of Operations”) contains
“forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the Securities Exchange Act
of 1934, as amended (the “Exchange Act”), that are intended to qualify for the “safe harbor” created by those sections. In addition, we may make forward-looking statements in
other documents filed with or furnished to the Securities and Exchange Commission (“SEC”), and our management and representatives may make forward-looking statements orally
or in writing to analysts, investors, representatives of the media and others. Forward-looking statements can generally be identified by the fact that they do not relate strictly to
historical or current facts and include, but are not limited to, statements using terminology such as “can”, “may”, “could”, “should”, “assume”, “forecasts”, “believe”, “designated
to”, “will”, “expect”, “plan”, “anticipate”, “estimate”, “potential”, “position”, “predicts”, “strategy”, “guidance”, “intend”, “seek”, “budget”, “project” or “continue”, or the
negative thereof or other comparable terminology regarding beliefs, plans, expectations or intentions regarding the future. You should read statements that contain these words
carefully because they:

● discuss our future expectations;

● contain projections of our future results of operations or of our financial condition; and

● state other “forward-looking” information.

We believe it is important to communicate our expectations. However, forward-looking statements are based on our current expectations, assumptions, estimates and projections
about our business and our industry and are subject to known and unknown risks, uncertainties and other factors. Accordingly, our actual results and the timing of certain events
may differ materially from those expressed or implied in such forward-looking statements due to a variety of factors and risks, including, but not limited to, those set forth under
Item 1, “Business,” Item 1A, “Risk Factors,” Item 7, “Management’s Discussion and Analysis of Financial Condition and Results of Operations,” and our consolidated financial
statements and notes thereto included in this report, those set forth from time to time in our other filings with the SEC, and the following factors and risks:

● Our ability to continue as a going concern;

● our lack of significant revenues;

● our limited experience in marketing our large-scale PCR based manufacturing platform;

● our history of net losses, which may continue, and our potential inability to achieve profitability;

● the possibility that we may require additional financing, which may involve the issuance of additional shares of common stock or securities exercisable for common

stock and dilute the percentage of ownership held by our current stockholders;

● difficulty in obtaining or inability to obtain, additional financing if such financing becomes necessary;

● the possibility we may fail to make timely payments on our secured convertible notes and, as a result, the noteholders enforcing their remedies and ultimately realizing

on their collateral which includes substantially all of our assets, including our intellectual property;

● volatility in the price and/or trading volume of our common stock;

● future short selling and/or manipulation of the price of our common stock;

● our inability to implement our short and long-term strategies;

● competition from products and services provided by other companies, including competition in the principal markets for our drug and biologic candidates and linear

DNA;

● potential difficulties and failures in manufacturing our products;

● loss of strategic relationships;

● dependence on a limited number of key customers;

● lack of acceptance of our products and services by potential customers;

● potential failure to introduce new products and services;

● difficulty or failure in expanding/and or maintaining our sales, marketing and support organizations and our distribution arrangements necessary to enable us to reach

our goals with respect to increasing market acceptance of our products and services;

● seasonality in revenues related to our cotton customer contracts;

1

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
● shifting enforcement priorities of U.S. federal laws relating to cannabis;

● inability to obtain and maintain regulatory approval in the pharmaceutical and biologic markets;

● inability of our collaborators, licensees, and customers to develop, obtain approval for and successfully commercialize products that incorporate our technology;

● inability of us, our collaborators, or customers to develop and timely manufacture complex biologic products and their components to exacting quality and safety

standards;

● inability to attract and retain qualified scientific, production and managerial personnel, including of Dr. Hayward, our Chief Executive Officer;

● failure to maintain the listing on, or the delisting of our securities from, The NASDAQ Capital Market;

● conflicts of interest with affiliates and related parties with whom we have engaged or entered into transactions;

● inability to compete effectively in the industries in which we operate;

● lack of success in our research and development efforts for new products;

● failure to manage our growth in operations and acquisitions of new technologies and businesses;

● inability to protect our intellectual property rights;

● intellectual property litigation against us or other legal actions or proceedings in which we may become involved;

● unauthorized disclosure of sensitive or confidential data (including customer data) and cybersecurity breaches; and

● adverse changes in worldwide or domestic economic, political or business conditions.

All forward-looking statements and risk factors included in this Annual Report on Form 10-K are made as of the date hereof, based on information available to us as of such date,
and we assume no obligations to update any forward-looking statement or risk factor, unless we are required to do so by law. If we do update one or more forward-looking
statements, no inference should be drawn that we will make updates with respect to other forward-looking statements or that we will make any further updates to those forward-
looking statements at any future time.

Forward-looking statements may include our plans and objectives for future operations, including plans and objectives relating to our products and our future economic
performance, projections, business strategy and timing and likelihood of success. Assumptions relating to the foregoing involve judgments with respect to, among other things,
future economic, competitive and market conditions, future business decisions, and the time and money required to successfully complete development and commercialization of
our technologies, all of which are difficult or impossible to predict accurately and many of which are beyond our control.

Any of the assumptions underlying the forward-looking statements contained in this Annual Report on Form 10-K could prove inaccurate and, therefore, we cannot assure you
that the results contemplated in any of such forward-looking statements will be realized. Based on the significant uncertainties inherent in these forward-looking statements, the
inclusion of any such statement should not be regarded as a representation or as a guarantee by us that our objectives or plans will be achieved, and we caution you against
relying on any of the forward-looking statements contained herein.

Our trademarks in the United States include Applied DNA Sciences®, SigNature® molecular tags, SigNature® T molecular tags, fiberTyping®, DNAnet®, digitalDNA®, SigNify®,
BackTrac®, Beacon® and CertainT® All trademarks, service marks and trade names included or incorporated by reference in this Annual Report on Form 10-K are the property of
their respective owners, including, without limitation, the PimaCott®, HomeGrown® LoneStar™ and HomeGrown Acala™ marks owned by Himatsingka America, Inc. and/or its
affiliates.

ITEM 1.

BUSINESS.

Overview

Using our large scale polymerase chain reaction (PCR) based manufacturing platform, we manufacture large quantities of linear DNA for various markets. Whether for supply chain
security, brand protection, law enforcement or drug or biologic applications, it is our goal to help establish secure flourishing environments that foster quality, integrity and
success. With secure taggants, high-resolution DNA authentication, and comprehensive reporting, our SigNature molecular tag technologies are designed to deliver what we
believe to be the greatest levels of security, deterrence and legal recourse strength. Under our wholly owned subsidiary, LineaRx, Inc. (LRx), we supply DNA for use in the in vitro
medical diagnostics, preclinical biotechnology and preclinical drug and biologic development and manufacturing markets. We are also engaged in preclinical and animal drug
candidate development directly and with collaborators focusing on therapeutically relevant DNA constructs manufactured via our PCR-based DNA production platform.

2

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
SigNature molecular tags, the core of our supply chain security technology platform, are what we believe to be nature’s ultimate means of authentication and supply chain security.
We believe our precision-engineered molecular tags have not been broken. Additional layers of protection and complexity are added to the mark in a proprietary manner. SigNature
molecular tags in various carriers have proven highly resistant to UV radiation, heat, cold, vibration, abrasion and other extreme environments and conditions. We work closely
with our customers to develop solutions that will be optimized to their specifications to deliver maximum impact. Our products and technology are protected by what we believe to
be a robust portfolio of patents and trademarks.

Using our tagging products and technology, manufacturers, brands, and other stakeholders can ensure authenticity and protect against diversion throughout a product’s journey
from manufacturer to use.

The core technologies of our supply chain security business are supplied as tag, test and track solutions for large complex supply chains. Our tag, test and track solutions allow
our customers to use molecular tags to mark objects in a unique manner that we believe cannot be replicated, and then identify these objects by detecting the absence or presence
of the molecular tag. We believe that our disruptive tracking platform offers broad commercial relevance across many industry verticals. Our underlying strategy in the tagging
business is to become a solutions provider for supply chains of process industries in which contracts for our products and services are larger and of longer duration as compared
to our historic norms, where the benefits to customers and consumers are more significant, and where our forensic security and traceability offer a unique and protected value.
Consumers, governments and companies are demanding details about the systems and sources that deliver their goods. They worry about quality, safety, ethics, and the
environmental impact. Farsighted organizations are directly addressing new threats and opportunities presented by this question: Where do these goods come from? This is the
question and the concerns we are beginning to address for a growing number of companies. We supply key building blocks for creating secure supply chains with traceability of
goods, which in turn can help ensure integrity in supply, honest sales and marketing claims, and ethical and sustainable sourcing.

Customers using our PCR-produced linear DNA products and services for use in vitro medical diagnostics, preclinical biotechnology research and preclinical drug and biologic
development and manufacturing receive DNA product we believe is made cleaner and faster than historical manufacturing methods, thereby offering the opportunity for increased
efficiency and turnaround times in their processes. We are also engaged in preclinical and animal drug candidate development activities focusing on therapeutically relevant DNA
constructs manufactured via our PCR-based production platform. We seek to develop, acquire and commercialize, along or with partners, a diverse portfolio of nucleic acid based
drugs and biologics based on PCR-produced linear DNA which we believe will improve existing nucleic acid based therapeutics or to create new nucleic acid based therapeutics
that address unmet medical needs.

3

 
 
 
 
 
 
 
 
Corporate History

We are a Delaware corporation, which was initially formed in 1983 under the laws of the State of Florida as Datalink Systems, Inc. In 1998, we reincorporated in the State of Nevada,
and in 2002, we changed our name to our current name, Applied DNA Sciences, Inc. In December 2008, we reincorporated from Nevada to the State of Delaware.

Our corporate headquarters are located at the Long Island High Technology Incubator at Stony Brook University in Stony Brook, New York, where we established laboratories for
the manufacture of molecular tags, product prototyping, molecular tag authentication and bulk DNA production. The address of our corporate headquarters is 50 Health Sciences
Drive, Stony Brook, New York 11790, and our telephone number is (631) 240-8800. We maintain a website at www.adnas.com where general information about us is available. The
information on, or that may be accessed through, our website is not incorporated by reference into and should not be considered a part of this report.

Industry Background

Supply chain security

Supply chains are the systems used by companies to obtain products and services for resale, their own consumption or as a component in a product or service that they then
resell. Supply chains often include the sourcing of raw materials, their processing in various stages to create products, and transportation and logistics to move goods both within
the supply chain process and to the final consumer. Many different companies may be part of a supply chain, and often the owner of the supply chain has limited ability to oversee
and supervise all components of its supply chain. Supply chain security refers to efforts to enhance the security of the supply chain. It combines traditional practices of supply
chain management with the security requirements driven by threats such as terrorism, piracy and theft. We focus on two particular parts of supply chain security, the identity of
goods to detect substitution of specified inputs with something else, often a cheaper, inferior input and the traceability of goods to a point in its lifecycle. For example, a company
might specify that sheets be made of high quality pima cotton but the company that wove the material for the sheets substituted cheaper and inferior upland cotton. We call a
supply chain with such security problems a leaky supply chain. Leaky supply chains create significant and growing problems to companies in a wide range of industries as well as
governments and individuals worldwide. Large retailers assemble sprawling networks of suppliers in developing countries to produce their goods at cheaper cost, underscoring
the difficulties of policing a global supply chain. This is a global problem that only appears to be increasing. Leaky supply chains allow materials to become diluted, diverted or
counterfeited, devaluing corporate reputations, potentially causing health and safety concerns, and hindering investment, and may cost hundreds of thousands of people their
livelihood every year. In addition, a company with a leaky supply chain has essentially been cheated, since they paid a premium price for an inferior substitution.

As more and more companies begin to address the problem of supply chain security, we expect that different systems will compete to be the leading standards by which products
can be tracked across world markets. To ensure only genuine products are entering the marketplace requires cutting edge technology. Historically, leaky supply chains and other
types of fraud have been combated by embedding various authentication systems and rare and easily distinguishable materials into products; technologies such as radio
frequency identification (“RFID”) devices, holograms or integrated circuit chips onto packaging; magnetic strips in automatic teller machine cards; banknote threads on currency;
elemental taggants in explosives; and radioactivity and rare molecules in crude oil. We believe these techniques are effective but have generally been reverse-engineered and
replicated which limit their usefulness as forensic methods for authentication of the sources of products and other items.

Brand Protection

Establishing a strong brand is pivotal to business success, as it is how a company is perceived by the customer. We believe that protecting that brand is as important.
Counterfeiting affects brands across the globe and effective brand protection strategy has become imperative for companies. Many customers do not even realize that they have a
counterfeit product, attributing the poor quality to the brand thus tarnishing its name. A recent Organization for Economic Co-operation and Development (OECD) report (June 23,
2017) reiterates a number of trends that have been evident for more than a decade – virtually all brands are being counterfeited, and counterfeit and pirated products are originating
from virtually all economies on all continents. Counterfeiters are improving their logistics networks, manipulating transit routes, exploiting governance gaps and taking advantage
of the huge growth in online shopping, thereby underlining the need for secure supply chains to protect brands. Consumer safety and satisfaction, brand reputation and revenues
can be adversely impacted by counterfeiting. Our SigNature molecular tags can be applied to many products, affording quick and definitive identification of authentic products,
and aiding in brand protection efforts.

Law Enforcement Applications

Burglaries, car theft, and cash-in-transit robberies are worldwide problems begging for a solution. The United States leads the world in the occurrence of home burglaries, with a
burglary occurring about every 18 seconds in the U.S. (The SafeWise Report - September 13, 2017). Interpol reported that for the year ending December 31, 2017, they had received
7.2 million records of reported stolen motor vehicles from 126 different countries (Interpol — Database Statistics). According to the FBI, there were an estimated 765,484 motor
vehicles stolen in the United States in 2016 and the value of the stolen motor vehicles was approximately $5.9 billion. These crimes have wide-ranging impacts, affecting law
enforcement agencies, insurance companies, legislative bodies, and justice departments.

4

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Asset identification, management, protection and authentication solutions that deliver value to the customer are critical components of any successful theft deterrent program. In
addition to tagging assets with a unique mark to prevent theft and facilitate return of stolen goods, it is imperative that would-be thieves know that the items are marked and that
law enforcement is trained to properly identify recovered property. Forensic marking of home assets, including automobiles, uses technology to code valuables at risk of theft to
identify burglars, linking them directly with a crime scene. Over the years, authorities have found it difficult to obtain convictions of thieves in possession of suspected stolen
property unless the true owner can be identified.

Nucleic Acid-Based Therapeutics

Nucleic acid-based therapeutics have emerged as a new class of drugs and biologics for treating unmet medical needs. Gene therapy, which includes adoptive cell therapy, DNA
vaccines and RNA-based therapies, is the foundation for the current fast-paced medical revolution. All gene therapies are driven by DNA, which is required in large scale. As of
January 2018, almost 2600 gene therapy clinical trials have been completed, are ongoing or have been approved worldwide (The Journal of Gene Medicine: Gene Therapy Clinical
Trials Worldwide to 2017; An Update -March 25, 2018). To date, DNA for gene therapies has been supplied via bacterial plasmids. Bacterial plasmid must be purified to remove
bacterial toxins and native bacterial DNA before therapeutic use, a process that increases manufacturing time and complexity. We believe PCR-produced DNA is a better
alternative than plasmid DNA for gene therapy. Through the use of our PCR-based manufacturing platforms, we feel we are well situated to supply DNA to the growing nucleic
acid-based drug and biologic markets. Therapeutics utilizing our PCR produced linear DNA will require clinical trials and approval by the Food and Drug Administration (“FDA”)
which may not occur for many years, if at all.

Products and Services

SigNature® molecular tags, SigNature® T molecular tags, fiberTyping®, DNAnet®, SigNify® BackTrac®, Beacon® and CertainT® comprise our principal security technology
platform. The large-scale production of specific DNA sequences is used in the diagnostics and reagent industries. Contract research and drug development and commercialization
relating to PCR-produced DNA constructs forms the basis of LRx.

Signature Molecular Tags

SigNature Molecular Tags. The SigNature molecular tag is our patented molecular taggant technology, at the core of our platform. It provides forensic power and protection for a
wide array of applications. Highly secure, robust and durable, SigNature molecular tags are an ingredient that can be used to fortify brand protection efforts; strengthen supply
chain security; and mark, track and convict criminals. Through our SigNature molecular tags, custom DNA sequences can be embedded into a wide range of host carriers including
natural and synthetic fibers, ink, varnish, thread, metal coatings, and pharmaceuticals and nutraceuticals. SigNature molecular tags can be made resistant to challenging
environments such as heat, cold, vibration, abrasion, organic solvents, chemicals, UV radiation and other extreme environmental conditions, and so can be identified for numerous
years after being embedded directly, or into media applied or attached to the item to be marked. Each individual molecular tag is recorded and stored in a secure database so that we
can later detect it using a simple spot test, or the molecular tags can be forensically analyzed in our laboratories to obtain definitive proof of the presence or absence of a specific
SigNature molecular tag (e.g., one designed to mark a particular product). Our in-lab forensic testing capability delivers an expert witness Certificate of DNA Authentication
(“CODA”). Because DNA is one of the densest information carriers known, and can be amplified with high fidelity, only minute quantities of SigNature molecular tags are
necessary for successful analysis and authentication. As a result, SigNature molecular tags can fold seamlessly into production and logistics workflows at extremely low
concentrations.

SigNature molecular tags have been subjected to rigorous testing by the Idaho National Laboratory, a U.S. National Laboratory, by CALCE (the Center for Advanced Life Cycle
Engineering), the largest electronic products and systems research center focused on electronics reliability, and by verified procedures in our laboratories. The molecular tag has
passed all tests across a broad spectrum of materials and substrates, and has met key military stability standards. SigNature molecular tags have also passed a strenuous “red-
team” vetting on behalf of the U.S. Defense Logistics Agency.

SigNature molecular tags now exist on hundreds of millions of commodity quantities ranging from consumer product packaging to microcircuits to cotton and synthetic fibers; to
our knowledge, none has ever been copied.

SigNature T Molecular Tags and fiberTyping

SigNature T Molecular Tags. SigNature T molecular tags are a unique patented tagging and authentication system specifically designed for textiles and apparel. Specially
engineered to adhere tenaciously to textile substrates, including natural and synthetic fibers, SigNature T molecular tags are resistant to standard textile production conditions.
The result: an enduring forensic level molecular tag that remains present from the fiber stage through to the finished product.

5

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Our SigNature T technology allows for better quality control and assurance at any point in the supply chain. SigNature T molecular tags are currently used for brand protection
efforts and raw material source compliance programs. For example, American grown cotton fibers can be tagged at the gin in the United States, verified as “American grown” and
then traced through every step of the supply chain.

fiberTyping. Our patented cotton genotyping platform, known as “fiberTyping,” described below, complements our SigNature T molecular tag system. fiberTyping is employed to
identify the genus and species of the fibers before or after they are tagged with SigNature T molecular tags. fiberTyping cannot be used to provide unique identity of a specific
cotton through the supply chain.

fiberTyping is not a molecular tag, but a genotyping test of native cotton fiber DNA, which gives a clear result that determines whether the intended “nature-made” endogenous
cotton DNA is present in fiber, yarn or fabric. Samples from the primary material are sent to our forensic labs for DNA analysis and authentication. Cotton classification and the
authentication of cotton species after cotton has left its place of origin are issues of global significance, important to brand owners and to governments that must regulate the
international cotton trade. The use of endogenous DNA to identify the cotton fiber content in textile supply chains, along with the SigNature T molecular tag system is a
significant opportunity for brand license holders to control their intellectual property, for brands to shield themselves against legal liabilities, and for governments to improve their
ability to enforce compliance with trade agreements between nations.

We believe that our proprietary DNA extraction protocols and methodologies are more effective than existing forensic systems. We believe that the combination of our SigNatureT
molecular tags and fiberTyping solutions cover the forensic authentication market for textiles and that the related protocols we have developed may be applicable to multiple
industry verticals (such as ingredients in nutraceuticals and cannabis) and can mark and authenticate products at every stage of their life cycle, from beginning to end.

DNAnet, Smart DNA and Backtrac

Recognizing that DNA-based evidence is the cornerstone of modern-era law enforcement, we have developed what we believe to be the ultimate crime fighting tools – currently
being used in vehicle and home asset marking, as well as commercial applications.

These molecular tags can be used to definitively link evidence and offenders to specific crime scenes. As the crime is investigated, the fluorescing molecular marker can assist
police in linking the offender and stolen items to a specific crime scene, creating a greater ability to identify and convict.

These long-lasting tagging solutions contain unique molecular tags that can help return stolen or lost property to its rightful owner.

Beacon

Beacon locked optical markers deliver secure real-time inspection capabilities. A unique patented encrypted mechanism creates a protected, covert screening tool that can be easily
adapted to packaging, security labels and high–value assets through inks, varnishes and coatings. When Beacon locked optical markers are combined with SigNature molecular
tags, a strong and flexible security and screening solution is created where authenticity and provenance can be determined with confidence.

SigNify

Developing a secure method for real-time, in-field screening of molecularly-tagged items has long been a priority for us. We believe that standard fluorophores, up-converting
phosphors, holograms and other more-traditional screening tools provide little to no defense against counterfeiting. We believe that secure in-field inspection backed with
forensic-level molecular tag authentication is the key to maintaining a well-defended supply chain or asset management program.

The SigNify IF portable DNA reader provides definitive real-time authentication of SigNature and SigNature T molecular tags in the field. With SigNify IF, Signature molecular tags
become a true, front-line solution for supply chain integrity.

 Information Technology Systems

Applied DNA Sciences Portal. The CertainT and other customer applications include the use of a software platform that enables customers to manage the security of company-
marked goods from point of marking to point of authentication or validation to end of life. The base platform is configurable to customer requirements which differ by vertical
market, company business process and IT environment. Basic functions offered include molecular tag inventory management, program training and communications, a database of
marked items information, associated documents and images, chain of custody and location tracking, sample authentication processing and CODA downloads, and other
administrative functions. Designed for either cloud or local operation, the system supports mobile data capture using bar codes or other technologies. The system is architected as
the controller and repository for other validation and authentication devices such as our SigNify DNA Readers, DNA Transfer Systems, and other third party devices and is
designed to share data with third party applications through standard interfaces.

6

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DNA Transfer Systems and Cannabis Tracking System. Our DNA Transfer Systems and Cannabis Tracking System are developed for DNA marking applications which are high
volume with a need for monitoring and control. They are computer based, fully automated, offer remote internet access for real-time monitoring and can be configured for
application-specific alerts and reporting online. They are being used to mark cotton at six U.S. cotton gins in the 2018-2019 ginning season and one location in Australia.

CertainT Supply Chain Platform

CertainT helps brands confirm their product’s authenticity and origin with certified, trust, transparency and traceability through the seamless amalgamation of several of our
platform technologies to tag, test and track. The CertainT trademark indicates use of the CertainT tagging, testing and tracking platform to enable proof of product claims for any
material, item or product. Secure and proven, the CertainT Platform helps manufacturers, brands or other commercial organizations deliver on their promise that customers are
buying products that are ethically-sourced, safe and authentic.

Large-scale production of specific DNA sequences using PCR.

Our patented Triathlon™ PCR systems allow for the large-scale production of specific DNA sequences. The systems are computer-controlled, self-contained and modular. DNA
sequences produced through our processes and systems are being used by customers as components of diagnostic tests and reagents, which provide us the opportunity to
cross-sell our DNA-based supply chain security solutions to this installed base and others. We believe we have the ability to manufacture longer DNA sequences valuable in gene
therapies, adoptive cell therapies (such as CAR T), DNA vaccines, RNA therapies and diagnostics, with what we believe is a distinct competitive advantage in cost, cleanliness,
and time-to-market. These types of DNA are distinct from our DNA security markers and represent a potential new entry into medical markets, where we believe there are
opportunities for our broader platform. Customers using our PCR-produced linear DNA products and services for use in in vitro medical diagnostics, preclinical biotechnology
research and preclinical drug and biologic manufacturing receive DNA product that we believe is made cleaner and faster than historical manufacturing methods, thereby offering
the opportunity for increased efficiency and turnaround times in their processes.

Contract Research

Under LRx, we act as a contract research organization for the nucleic acid-based medical and biologic markets. In addition, LRx is providing contract research services to several
RNA based drug and biologic customers for preclinical studies. These services include the design, development and manufacture of PCR-produced DNA templates for RNA.

Therapeutics

In addition, we seek to develop, acquire and commercialize, ourselves or with partners, a diverse portfolio of nucleic acid-based drugs and biologics based on PCR-produced linear
DNA to improve existing nucleic acid-based therapeutics or to create new nucleic acid-based therapeutics that address unmet medical needs. We are also engaged in preclinical
and animal drug candidate development activities focusing on therapeutically relevant DNA constructs manufactured through our large scale PCR production systems. LRx uses
its PCR systems to rapidly produce customized DNA for use by our CRO/CMO clients, our preclinical drug and biologic clients and partners, and for our own preclinical nucleic
acid-based drugs and biologics under development in the field of CAR T-cell immunotherapy.

Our Strategy

The core technologies of our supply chain security business are supplied as tag, test and track solutions for large complex supply chains. Our tag, test and track solutions, allow
our customers to use molecular tags to mark objects in a unique manner, and then identify these objects by detecting the absence or presence of the molecular tag.

We believe that our disruptive tracking platform offers broad commercial relevance across many industry verticals. Our underlying strategy in the tagging business is to become a
solutions provider for supply chains of process industries in which contracts for our products and services are larger and of longer duration as compared to our historic norms,
where the benefits to customers and consumers are more significant, and where our forensic security and traceability offer a unique and protected value. Consumers, governments
and companies are demanding details about the systems and sources that deliver their goods. They worry about quality, safety, ethics, and the environmental impact. Farsighted
organizations are directly addressing new threats and opportunities presented by this question: Where do these goods come from? This is the question and the concerns we are
beginning to address for a growing number of companies. We supply key building blocks for creating secure supply chains with traceability of goods, which in turn can help
ensure integrity in supply, honest sales and marketing claims, and ethical and sustainable sourcing.

Customers using our PCR-produced linear DNA products and services for in vitro medical diagnostics, preclinical biotechnology research and preclinical drug and biologic
manufacturing receive DNA product made we believe cleaner and faster than historical manufacturing methods, thereby offering the opportunity for increased efficiency and
turnaround times in their processes. We are also engaged in preclinical and animal drug candidate development focusing on therapeutically relevant DNA constructs manufactured
via our PCR-based production platform. We seek to develop, acquire and commercialize, along with partners, a diverse portfolio of nucleic acid-based therapeutics based on PCR-
produced linear DNA to improve existing nucleic acid-based therapeutics or create new nucleic acid-based therapeutics that address unmet medical needs.

7

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Our products and services are offered in the United States, Europe and Asia. At the present time, we are focusing our efforts on textile and apparel, pharmaceuticals and
nutraceuticals, microcircuits and other electronics, legal cannabis and PCR-produced linear DNA products, as well as and services for in vitro medical diagnostics, preclinical
biotechnology research and preclinical biotherapeutic manufacturing. Currently, approximately twenty percent of our annual revenue comes from the textile market. The cotton
ginning season in the United States takes place between September and March each year; therefore, revenues from our cotton customer contracts may be seasonal and recognized
primarily during our first and fourth fiscal quarters, which may cause operating results to fluctuate significantly quarterly and annually. The basic technology we use in various
markets is very similar, and we believe our solutions are adaptable for many types of products and markets. To date, the substantial portion of our revenues has been generated
from sales of our SigNature and SigNature T molecular tags, our principal supply chain security and product authentication solutions. We expect to grow revenues from sales of
our SigNature molecular tags, SigNature T molecular tags, SigNify and CertainT offerings as we work with companies and governments to secure supply chains for various types
of products and product labeling throughout the world. In addition, we expect to continue to grow revenues from PCR-produced linear DNA products and services using our
Triathlon™ PCR systems.

The basic technology we use in various markets is very similar, and we believe our solutions are adaptable for many types of products and markets.

Target Potential High-Volume Markets

We will continue to focus our efforts on target vertical markets that are characterized by a high level of vulnerability to leaky supply chains, product diversion and a lack of
security. We also intend to expand into additional related high volume markets.

Pursue Strategic Acquisitions and Alliances

We intend to pursue strategic acquisitions of companies and technologies that strengthen and complement our core technologies, improve our competitive positioning, allow us to
penetrate new markets, and grow our customer base. We also intend to work in collaboration with potential strategic partners in order to continue to market and sell new product
lines derived from, but not limited to, DNA technology.

Present Markets:

Textiles and Apparel

Textile identity and the authentication of a product’s origin, are issues of global significance, important to brand owners for quality assurance and compliance, and to governments
that must regulate international trade, enforce textile labeling, and protect consumers. We believe that CertainT, an integrated platform to Tag, Test, and Track fiber, yarn, fabrics all
the way to finished goods, enables brands and manufacturers to preserve the integrity authenticity and quality of the source materials in a global supply chain. As a result,
consumers will have confidence that claims and ingredients listed on the label are proven in the finished product. CertainT molecular business solutions are relevant to natural
fibers like cotton, wool, cashmere, down and feather, and leather, as well as man-made fiber, recycled polyester, viscose and other synthetic products used in apparel, footwear and
home textiles globally. The molecular tag is robust, and inert. It has no impact on the form or function of raw materials or end products and is persistent throughout the
manufacturing process. The information content of each unique SigNature T tag can be assigned with precision to a supply chain objective. Thus, SigNature T tagged materials
have their own identity and may offer, for example, a unique story of where, when, and/or how they were made. The flexible nature of SigNature T technology facilitates easy
addition of the tag at virtually any stage of textile production. Molecular tag analysis verifies goods identity as the corner stone of the platform. Testing can be conducted at
Applied DNA’s ISO 17025 accredited forensic laboratories in Stony Brook, New York, or in the field, for some validated products, using portable processes and equipment.

Our Market Response

As part of the CertainT platform, our patented SigNature T molecular tag technology for molecular tagging and authentication has been proven to be scalable and commercially
applicable in integrated textile supply chains, in cotton as well as recycled polyester and is currently in use by our customers. Our SigNature T molecular tag commercial program
involves the creation of unique SigNature T molecular tags that can be used to tag a customer’s cotton fiber at the ginning stage. Installed in October 2017, our updated fully
automated, secure DNA Transfer Systems allow for traceability and monitoring of all molecularly-tagged cotton at multiple gins in Arkansas, Texas and California. During fiscal
2018, a DNA Transfer System was installed in a gin in Australia. The DNA Transfer Systems allow for expansion of tagging at other gins to support increased demand for tagging
in future years.

Once tagged, the cotton fiber may be authenticated for textile identity from grower to ginner to spinner to manufacturer to distributor to retailer. At each step of the process, its
textile identity will be tested to link the original cotton fiber to finished product, preserving the authenticity of the product and the integrity of the supply chain. SigNature T DNA
tags are being used to mark premium Pima cotton fiber, known as PimaCott® and are also beginning to be used to mark Upland cotton, under the HomeGrown™ LoneStar™ and
HomeGrown Acala™ trademarks. As the cotton ginning in the U.S. takes place sometime between September and March each year, it is possible that revenues from this business
will be seasonal.

8

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
In June 2017, we entered into a new licensing agreement with Himatsingka America, Inc., which is part of the Himatsingka Group. (“Himatsingka America”), a leading supplier of
home textiles. This agreement terminates an earlier licensing agreement dated March 25, 2015 between Divatex Home Fashion, Inc. (a predecessor to Himatsingka America) and the
Company. Under the terms of the Agreement, Himatsingka America will be solely responsible for promoting, marketing and selling on a worldwide basis the Company’s technology
with respect to finished and unfinished cotton products. The Agreement grants Himatsingka America an exclusive license to use our technology in respect of cotton, subject to
certain carve-outs including governmental users, non-commercial trade associations and others. The Agreement has a term that continues until June 23, 2042, except in the case of
patents, in which case the term continues with respect to a patent until such patent is no longer in effect. The Agreement also provides that Himatsingka America will make royalty
payments on a quarterly basis in arrears in the event that our technology is used on non-home products. Himatsingka America is responsible for the inspection and compliance
within the supply chain.

Himatsingka America is generally required to use our technology during the term of the Agreement, subject, among other things, to their customers’ requirements. We have
established an independent testing laboratory in Ahmedabad, India, which is required by the agreement. Finished products made from this tagged fiber are offered for sale under
the PimaCott®, HomeGrown®, LoneStar™ and HomeGrown Acala™ content branded labels. The Agreement includes customary mutual indemnification provisions. See also the
information under the caption “—Distribution of our Products and Commercial Agreements—Himatsingka America.”

In January 2016, we signed a cooperative research and development agreement (“CRADA”) with the United States Department of Agriculture (“USDA”) to collaborate on the
development of genotyping assays for cultivars from specific geographic regions of the world. This agreement was extended on April 1, 2018 for an additional five years. It is
important to be able to differentiate cotton based on country of origin to help avoid “Conflict Cotton”, cotton grown using child labor or other undesirable practices. We believe
this will assist the cotton industry in protecting the quality and traceability of the products and help protect their economic investments.

For recycled polyester, over 15 million pounds of fiber have been initially tagged with our SigNature T molecular tagging technology.

On June 28, 2017, we signed a multi-year license agreement with GHCL Limited, a global manufacturer of home textiles, to provide CertainT platform services in connection with
source-verified, polyethylene terephthalate (PET) and recycled PET (rPET post-consumer) in select home textile products. PET is the clear plastic best known for its use in water
bottles, and is the most widely recycled plastic in the world. GHCL is using our CertainT platform in connection with PET and/or recycled PET blended bed sheets, pillowcases, and
shams products sold in-store or online in the United States. GHCL has also licensed our CertainT trademark for use on its products, as well as for promotional, marketing and sales
materials. The agreement provides for guaranteed minimum annual revenues in order to maintain exclusivity during the renewal period, as well as trademark licensing royalties to
us. GHCL is using our CertainT platform for verifying PET and recycled PET authenticity from source to retail shelf. With this platform, GHCL assures that any of its textile
products using PET and recycled PET will contain the original source raw materials. We will provide our patented and proprietary tagging, testing and tracking services to GHCL as
a CertainT licensee. As part of the platform, Applied DNA’s molecular tag is extruded into recycled components that create recycled PET fiber, with no impact to performance or
quality of the fiber or filament yarns. Thereafter, any piece of CertainT-tagged textiles can be forensically authenticated by detecting the molecular tag in the recycled PET fiber,
ensuring its authenticity and origin. During October 2018, GHCL launched CIRKULARITY™, a new brand of eight lines of bedding supporting the circular economy. These lines
center on “reduce, reuse and recycle”. REKOOP®, the inspiration behind CIRKULARITY, is a brand of bedding products made from recycled plastic (rPET) and is the first bedding
product to use our CertainT platform. REKOOP uses our CertainT platform to trace and authenticate the post-consumer recycled polyester plastic in its bed sheets, pillowcases,
and shams throughout the entire supply chain.

On July 11, 2017 we signed a new multi-year exclusive license agreement with Loftex Home, LLC (“Loftex”), a well-respected manufacturer of high-quality towels and home textiles.
Under a prior agreement entered into during March 2017, we agreed to provide our CertainT™ platform services to Loftex to verify the authenticity and origin of rPET (post-
consumer) used in bath and beach towels. This new multi-year agreement between the two companies is now exclusive for bath and beach towels in the United States, non-
exclusive for plush throws and bath rugs, and provides for long term minimum annual revenues, in order to maintain exclusivity, as well as trademark licensing royalties to us.

For information on our statement of work with American & Efird and research project with BLC, please see “Distribution of our Products and Commercial Agreements.”

Microcircuits and other electronics

The vast majority of counterfeits discovered in military equipment are semiconductors, the stamp-sized silicon wafers that act as the “brains” of nearly every type of modern
electronic system. According to an article in DefenseOne (Counterfeits Can Kill U.S. Troops. So Why Isn’t Congress and DoD Doing More to Stop it? — August 8, 2013), the U.S.
military is an important consumer of these tiny products; a single F-35 Joint Strike Fighter jet is controlled by more than 2,500 semiconductors.

One of the reasons counterfeit microcircuits are a major concern in weapons procurement is because the chips, which control targeting accuracy and other critical parameters, can
wreak havoc if they do not perform to specifications. They can also be a means of sabotaging weapon systems if covertly supplied by a hostile government through seemingly
legitimate companies.

The Defense Logistics Agency (DLA) is the nation’s combat support agent for logistics. DLA The Agency manages over 5 million parts, supports more than 2,300 weapon
systems, and accounts for nearly 85% of the spare parts for our military forces. DLA’s reach extends far beyond DoD. The Agency supports Foreign Military Sales (FMS) to more
than 100 nations. DLA provides significant support to worldwide humanitarian relief, the Federal Emergency Management Agency (FEMA), and other federal, state, and local
customers.

9

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
The problem is not limited to the defense industry. According to an April 2016 report by OECD and the EU Intellectual Property Office, fake products are worth nearly $461 billion
per year, or roughly 2.5% of all global trade.

Our Market Response

On November 15, 2012, DLA began to require that defense contractors provide certain items that have been marked with DNA produced by us or our authorized licensees. This
requirement was in place for items falling within Federal Supply Class (FSC) 5962, Electronic Microcircuits, which have been determined to be at high risk for counterfeiting.

Beginning on December 15, 2014, DLA’s Electronic Product Test Center (“PTC”) in Columbus, Ohio began DNA marking all FSC 5962 microcircuits. This change created a
centralized, streamlined DNA marking process within DLA. On November 13, 2014, we were awarded a contract by DLA to provide DLA with SigNature DNA molecular tags and
related equipment, services and training. This contract was then extended through October 13, 2018. An additional follow-on two-year contract (plus one exercise year) to ensure
there is no lapse in support of the current DNA program at DLA’s PTC was signed on September 6, 2018.

In addition, on June 6, 2017, we were awarded a two-year, approximately $1.5 million competitive-bid development contract. The award, funded by the Office of the Secretary of
Defense on behalf of the DLA, runs from June 1, 2017 to May 31 2019, and was granted via a Rapid Innovation Fund (RIF) that provides DLA with innovative technologies that
can be rapidly inserted into acquisition programs to meet specific defense needs. Management oversight for this RIF contract is from DLA HQ located in Fort Belvoir, Virginia. This
firm-fixed price contract follows our prior RIF contract, described further below, that enabled us to develop counterfeit mitigation technologies based upon our proprietary DNA
platforms, that protect plastics, silicone elastomers, oils, bearings, fasteners and many other high-risk commodities that are procured by DLA on behalf of DoD. This contract will
extend our authentication platform to facilitate broader use in protecting high-risk or mission-critical material purchased by DLA.

This contract together with prior development contracts have strengthened our core capabilities to offer supply chain risk management solutions across an expanded range of
critical components used in defense, industrial and consumer markets.

On November 20, 2017 we signed a CRADA with the U.S. Army Research, Development and Engineering Command’s Edgewood Chemical Biological Center (“ECBC”) to study the
commercialization of ECBC’s innovative rapid, in-field DNA microarray technology for use in military and commercial supply chains. ECBC is the nation’s primary DoD technical
research organization for non-medical chemical and biological warfare defense.

Under the terms of the CRADA, a cooperative effort under the DLA RIF award secured by us in June 2017, ECBC’s subject matter experts and our science team will cooperatively
study the feasibility of commercializing ECBC’s in-field DNA detection technology in varied supply chains. ECBC’s hand-held in-field DNA microarray technology allows for
detection of a DNA taggant within a few minutes. The project goal is to demonstrate the system with our taggants introduced into standard inks or varnishes or onto other
surfaces, without the need for DNA amplification or other sample preparation, thus greatly simplifying in-field DNA detection.

Cash-in-Transit

Cash-in-transit businesses transport and store cash and ATM cassettes. In the U.K. alone, there is an estimated £500 billion being transported each year (approximately $755
billion as of December 2015) or £1.4 billion per day (approximately $2.2 billion) (British Security Industry Association: “Combating Cash Delivery Crime”). The nature of this
business makes cash-in-transit an attractive target for criminals and as a result the industry invests in excess of £100 million (approximately $151.1 million) per year in security
equipment and devices. Since 2009, the number of CViT (Cash and Valuables in Transit) convictions attributed to the use of SigNature DNA in cash boxes has risen to more than
125, with prison sentences of over 610 years. SigNature DNA forensic tags are helping Police across Europe to identify stolen cash and to link the evidence directly to the
perpetrators. According to the FBI, in 2016, over 40 people were killed or injured in over 4,000 robberies of financial institutions across the nation (Bank Crime Statistics 2016 - FBI).

Our Market Response

We incorporate our SigNature DNA molecular tags in cash degradation inks that are used in the cash-in-transit industry in countries throughout the United Kingdom and other
countries within Europe. This solvent-based ink marks bank notes if the cash box is compromised and has the ability to penetrate the bank notes rapidly and permanently. We
believe our SigNature DNA molecular tags are more resilient and detectable than other competing technologies.

To date, the use of SigNature DNA in the cash handling industry has allowed our products to facilitate the convictions of more than 125 criminals across Europe involved in cash-
in-transit crime with aggregate prison sentences of over 610 years. SigNature DNA has been used since 2008 in Europe within the ink and / or smoke systems of Intelligent Bank
Note Neutralisation Systems (“IBNS”), more commonly known as cash boxes and ATM cassettes. Unique, SigNature DNA molecular tags are incorporated into each IBNS during
manufacture.

10

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Consumer Asset Marking

Car crime is a very large and profitable business, costing billions of dollars per year and representing approximately one-third of all reported crime. It is estimated that approximately
70 percent of stolen cars are broken up and sold for spare parts, while the rest are given a false identity and sold, with many of those being exported to the Middle and Far East.

Everyone has assets they want to look after - from household goods such as TVs, jewelry and antiques to office equipment including computers and laptops. There are a wide
variety of valuable items that need to be uniquely identified and protected from theft. Forensic marking of home assets uses technology to code valuables at risk of theft to mark
burglars, linking them directly with a crime scene.

Over the years, authorities have found it difficult to obtain convictions of thieves in possession of suspected stolen property unless the true owner can be identified. If marked
items are stolen and later found, police can link them directly with the crime scene, not only allowing the property to be returned to its owner, but also increasing the chance of
convicting the thieves.

Our Market Response

We believe that DNAnet, Smart DNA and Backtrac enhance law enforcement effectiveness by providing forensic quality evidence. The DNAnet, SmartDNA and Backtrac Asset
Marking program provides a simple and cost-effective way for asset owners to deter crime and protect their property, a way for law enforcement to identify the rightful owners of
lost or stolen property, and a way to tell criminals…stay away because you will get caught!.

Our Smart DNA is being used to protect the automobiles of one major European automotive manufacturer against the theft of their automotive parts after being imported into at
least one E.U. country. New cars are marked with a unique code applied at point of importation or delivery to the customer. Customer details are registered on a secure database.
The DNA molecular tag provides absolute identification to the vehicle. The molecular tags are covert and difficult to remove. If found, vehicles and their component parts are
traceable back to the car, from anywhere on the globe. If the car is stolen and recovered, police will be able to link the criminal to the crime, and will know exactly where to return the
vehicle. Highly visible warning stickers are displayed on the windshield of the car, deterring theft in the first place. To date, over 70,000 high-end cars have been marked with Smart
DNA.

Printing and Packaging

The scourge of counterfeiting in packaging has greatly intensified in recent years. Counterfeiting has spiked, causing detrimental health concerns for consumers, safety concerns
for law enforcement agencies, and financial concerns for businesses worldwide. As a result, the global anti-counterfeit packaging market is estimated to reach approximately
$206.57 billion by the year 2021, according to Markets and Markets.

Billions of dollars per year are at stake for companies as they seek ways to ensure that the products sold with their logos and branding are authorized and authentic. The
proliferation of counterfeiting requires brand owners and their converter/printer partners to work together to create a multi-layered protection plan so that their packaging and
labels protect their brands and deter those trying to profit at their (and their reputation’s) expense.

Counterfeiters have become so good at their unlawful activity that spotting the difference between legitimate and counterfeit products can be daunting. They have many ways to
subvert legitimate brands. They may take an out-of-date — but legitimate — product and sell it in packaging and labels that have been faked. Sometimes, everything — including
the packaging, labels and product itself — is counterfeit. Criminals might also use legitimate packaging with knock-off products.

Our Market Response

Our integrated platform of forensic level molecular tags and optical and digital technologies offers a high level of security and flexibility in a cost-effective and easy-to-use format
to suit the requirements and budget of most companies. They can be added to the varnish, ink or toner in labels and packaging to act as a trace without impacting the quality of the
substrate. Our SigNify IF reader or forensic laboratory process is required to detect the molecular tags and verify that a label is authentic. Proprietary optical and digital
technologies complement SigNature molecular tags with more rapid screening capability.

During September 2017 we entered into a strategic partnership with Videojet Technologies Inc. (Videojet). We have collaborated with Videojet in the design of co-branded
SigNature® molecular-tagged Videojet inks, and a co-branded printer that electronically restricts the use of ink cartridges to only those that contain SigNature molecular tagged
inks. The relationship brings the potential to empower the tagging of countless commercial items, all of which are candidates for a CertainT licensing agreement, enabling
traceability along the entire supply chain.

Integrating the technologies from both companies creates a world-class solution that will be offered to the many industries in which both companies are already engaged.
Videojet’s 325,000-installed base of printers, which code and mark well over ten billion products each day, is a testament to the power of continuous inkjet printing (CIJ)
technology. The initial offering utilizes Videojet’s newly released 1860 printer, which will be co-branded with us, along with co-branded Videojet inks that will incorporate our
unique SigNature molecular tag into each individual ink cartridge. The SigNature-enabled inks may be brand-specific, enabling each brand to tag, test and track their products from
source to shelf under a CertainT platform. Gaining this additional traceability, transparency, and ultimately trust between value chain partners will allow brands to offer a new level
of certainty to their customers that the products they are buying are authentic.

11

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Diagnostics and Reagents

DNA-based diagnostics is an emerging application area in the in-vitro diagnostics industry. DNA–protein adducts are popular across the medical diagnostics industry, where
these molecules aid in the determination of the incidence of a suspected disease caused by an organism or pathogen. Based on the amount of target DNA present, probes can be
used either directly to detect target DNA, facilitate the performance of targeting proteins or indirectly to target DNA through amplification that creates a number of copies of a
specific nucleotide. Increased automation of diagnostic tests, discovery of new diagnostic markets, rising investments in pharmaceutical and pharmacogenomics research, and
advancements in DNA array technologies are major growth facilitators for the DNA probes-based diagnostic products market.

According to an article from BCC Research, (“DNA Diagnostics Market to Almost Double by 2022 with 14.3% CAGR”), the DNA Diagnostics market will reach $23.8 billion in 2022.
The potential to provide accurate diagnosis and cost effectiveness over alternative diagnostic techniques are factors that supplement the growth of the DNA diagnostics market.
Recent figures suggest that globally, approximately 32.5 million people are living with cancer (as of 2012) with 14.5 million people in the U.S. living with cancer (as of 2014) and 36.7
million with HIV/AIDS (as of 2015) (International Agency for Research on Cancer, Cancer Fact Sheets, All Cancers (excluding non-melanoma skin cancer), Estimated Incidence,
Mortality and Prevalence Worldwide in 2012; World Health Organization, Global Health Observatory (GHO) Data, Cancer Facts and Figures 2017, amFAR). These numbers, we
believe are set to increase consistently; however, advanced automated DNA diagnostics technologies such as next generation sequencing could play a crucial role in diagnosing
and curbing these diseases. (Allied Market Research, “DNA Diagnostics Market is Expected to Reach $19 Billion by 2020” (August 28, 2014))

12

 
 
 
 
 
 
 
Our Market Response

Following our acquisition of substantially all the assets of Vandalia Research, Inc. in September 2015, we are able to produce specific, high-quality DNA sequences with the PCR
production system known as Triathlon, which is well suited to meet these diagnostic and reagent needs. Cell-based DNA production methods are often complicated by impurities.
In contrast, we believe our PCR-based production method offers a high degree of purity and efficiency. In April 2017, we were awarded a five-year supply agreement with
FUJIFILM Wako Pure Chemical Corp. (formerly Wako Pure Chemical Industries, Ltd.) for the manufacture of bulk DNA for in vitro medical diagnostics. This supply agreement
includes quarterly DNA shipments and optional three-year renewals. Under this multi-year contract, our DNA is utilized in a medical diagnostic tool that aids in assessing disease.

Pharmaceutical Supply Chain

From cyber-attacks in large pharmaceutical companies like the one that affected a large global healthcare leader earlier this year to the rising opioid crisis, the pharmaceutical supply
chain has more risk inherent than ever before. Reducing supplier risk to help boost patient safety is becoming more important than ever to pharmaceutical companies.

The pharmaceutical industry also faces major problems relative to counterfeit, diluted, or falsely labeled drugs that make their way through healthcare systems worldwide, posing a
health threat to patients and a financial threat to drug makers and distributors. Counterfeit prescription pharmaceuticals are a growing trend, widely recognized as a public health
risk and a serious concern to public health officials, private companies, and consumers. The National Association of Boards of Pharmacy estimates that counterfeit drugs account
for 1% of all drugs sold in the United States. The World Health Organization (WHO) estimates the annual worldwide “take” from counterfeit drugs to be £13 billion (approximately
$19.6 billion as of December 2015), a figure that is expected to double by the end of this decade. In some countries, counterfeit prescription drugs comprise as much as 70% of the
drug supply and have been responsible for thousands of deaths in some of the world’s most impoverished nations, according to the WHO. The global pharmaceuticals and food
anti-counterfeiting market is expected to reach $160 billion by 2020. (Radiant Insights, “Global Pharmaceuticals and Food Anti-Counterfeiting Market Is Expected to Reach USD
160.32 Billion by 2020” (September 28, 2015))

In 2012, the WHO reported that in over 50% of cases, medicines purchased over the Internet from illegal sites that conceal their physical address have been found to be counterfeit
(WHO: Medicines: Spurious/falsely-labelled/falsified/counterfeit (SFFC) medicines Fact Sheet June 2012). According to the WHO, counterfeiting can apply to both branded and
generic products and counterfeit pharmaceuticals may include products with the correct ingredients but fake packaging, with the wrong ingredients, without active ingredients or
with insufficient active ingredients.

Based on this growing threat, many countries have started to address vulnerabilities in the supply chain by enacting legislation which, among other things, requires a
comprehensive system, most often referred to as serialization or in the United States as Drug Supply Chain Security.

Nearly 40 percent of the drugs Americans take are made outside of the United States, and about 80 percent of manufacturing sites of active pharmaceutical ingredients (APIs) used
in drugs manufactured in the United States are located outside our borders—in more than 150 countries, many with less sophisticated manufacturing and regulatory systems than
our own. In addition to the sheer volume of imports and foreign facilities, there has been an increase in the variety of sources, shippers, methods of transportation, and supply
chain complexity of products. Combined, these factors create great challenges to the FDA and industry in ensuring that all drugs and drug components are high quality and travel
safely throughout their complex supply chains. These factors also provide opportunities for criminals to adulterate drugs for economic or other malevolent reasons making it more
important than ever that supply chains be secured around the world. (U.S. Food and Drug Administration, “Counterfeit Drugs: Fighting Illegal Supply Chains” (February 27, 2014))

Our Market Response

On March 31, 2018, we entered into a License and Cooperation agreement and a related Supply Agreement with Colorcon, Inc. (“Colorcon”) for the use of our molecular tags in
Colorcon’s product offerings and access to our associated authentication technologies. Under the terms of the Agreements, we granted Colorcon exclusive worldwide right to use
our molecular tags and associated authentication technologies in film coatings for solid oral dosage form (“SOD”) applications, for which Colorcon is the largest global supplier,
and non-exclusive rights to use our technologies in inks and colorants for SOD applications. Pursuant to the Agreements, we will supply taggant and authentication materials to
Colorcon in exchange for long-term royalties on the sale of Colorcon products incorporating our molecular tags and on the sale of authentication services related thereto. Further,
the first of two milestone payments was payable to us at the signing of the Agreements. We will receive the second milestone payment upon initial approval by a regulatory
authority for application in a SOD pharmaceutical or nutraceutical product application. The Agreements generally expire on the later of October 1, 2032 or the last expiration date of
any patent licensed pursuant to the Agreements.

13

 
 
 
 
 
 
 
 
 
  
 
 
 
 
In April 2018, we filed our Drug Master File with the U.S. FDA to allow confidential information about the Chemistry, Manufacturing and Controls processes of our product to be
made available to the FDA for inspection should an end-user company choose to have FDA review of the addition of the Signature molecular tag to their product. In May 2018, the
FDA acknowledged receipt of our filing. We have completed the formulation of our SigNature tags with Colorcon, following the October 2011, the U.S. Food and Drug
Administration (the “FDA”) Final Guidance document on the use of so called “Physical-Chemical Identifiers” (PCIDs). The FDA Guidance stipulates that a PCID should be
pharmacologically inactive and present no risk of adverse reaction. The PCID cannot affect the efficacy of the drug. In addition, 11 categories of information about the PCID must
be satisfactorily addressed. We believe SigNature DNA may be able to fulfill these requirements. In addition, DNA identifier molecular taggants can be embedded at parts per
billion onto film coatings that cover many of the world’s leading brands of tablets. By integrating the Applied DNA molecular tags within already utilized film coatings of tablets,
we are offering a seamless solution for pharmaceutical company customers.

During January 2018, we entered into a Memorandum of Understanding with ACG to develop SigNature® molecularly tagged empty hard-shell capsules to enhance product
traceability and authentication. ACG is one of the world’s largest pharmaceutical and nutraceutical capsule manufacturers, with the empty capsules market estimated to exceed $2
billion by 2023. For information on our Memordandum of Understanding with ACG please see “Distribution of our Products and Commercial Agreements”.

Our unique DNA identifier mark-embedded in the ink of a unique serialized barcode used on packaging can provide a layered security foundation for a customer solution in this
market. Strengthening the bar codes to be utilized in the serialization process can be a potent approach to protecting the patient and bringing greater confidence to the brand of the
pharmaceutical company.

Cannabis

The legal cannabis industry is one of the fastest growing industries in the world. With a global CAGR of over 20%, a 2017 market size of over $17 billion, it is projected to be a $63
billion industry by 2024. Therefore, the legal cannabis industry represents an exciting opportunity for leveraging Applied DNA Sciences core capabilities in supply chain
management. By using our molecular tagging and tracking technologies, we believe we are very well positioned to address provenance concerns within the global cannabis supply
chain and its stakeholders.

In the United States, proof of provenance as to the origin of cannabis is an essential element of value in state-legal programs. Under the shadow and oversight of the federal
government, since cannabis remains a Schedule-1 drug, any state program must be cognizant of the tenants under which they operate their cannabis program. By federal law, it
remains illegal to transport cannabis across state lines and hence any state program has need to be able to discriminate if challenged between cannabis and products produced and
sold within the state and all others that may not be legal within the state.

Many international countries are already embarking on plans for their own cultivation and/or importation of cannabis and/or cannabis by-products and are not saddled with the
unique United States situation.

Our Market Response

During January 2018, we entered into an initial two-year $1 million contract for the development of molecular tracking systems for legal cannabis worldwide with TheraCann
International Benchmark Corporation, (“TheraCann”), a leading full service cannabis consultancy with operations in the US, Canada, Australia, Europe and South America, for the
integration of the Company’s SigNature® molecular tagging and testing technology into TheraCann’s seed-to-sale Enterprise Resource Platform (ERP) for legal cannabis
operations. Under the terms of the contract, the companies have entered into a development and marketing agreement whereby we will develop the technologies necessary to tag
and authenticate legal cannabis throughout the supply chain and seamlessly integrate tagging and authentication data into TheraCann’s ERP and blockchain. Together with our
expertise in the physical molecular tagging of various materials in numerous vertical markets, we jointly are well positioned to address the provenance concerns of the cannabis
industry on a global basis.

We have initially positioned our joint provenance solution under the banner of, “Etch Biotrace” which includes an end to end seed-to-sale solution, a blockchain offering, and the
power of our CertainT molecular tagging and tracking capabilities. It is the combination of both capabilities that allows us to be strongly positioned to serve the cannabis needs on
a global basis.

With both powerful tagging solutions, we are well poised to move to the next step which is a trial(s) with advanced thinking growers or processors as well as state programs that
are either about to launch or already have launched a cannabis program and are looking for ways to provide more control over their cannabis supply chain.

Agrochemicals

The agrochemical industry is faced with an increased prevalence of illegal trade, counterfeiting and brand piracy. From the adulteration and counterfeiting of leading herbicides,
pesticides and fertilizers with inferior materials, to the substitution of genetically modified seeds with low yield alternatives, crops are at risk more than ever. These issues threaten
company reputations, supply systems, export markets and government tax revenues.

14

 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
In Europe, Africa and other areas of the world, use of counterfeit and illegally traded pesticides is increasing. Untested and unregulated products may threaten the health of
farmers and consumers and pose risks to the natural environment. Counterfeit pesticides threaten the integrity of those industries that depend on the benefits of pesticide use.

Fighting counterfeit pesticides is a complex task. We believe that enforcement of regulations governing pesticide use is inadequate and has led in recent years to an increase in use
of illegal, counterfeit pesticides.

According to research by International Growth Center (2015), the vast majority of fertilizer samples from the Uganda study were substandard. Additionally, very few of the
allegedly improved seeds showed success in producing large crops. In short, the agricultural inputs sold at retail level in Uganda are often ‘fake’ or of very poor quality. In the
case of fertilizer, according to estimations by the Vietnam Fertilizer Association (2016), the country’s economy loses US$2 billion every year as a result of fake products. According
to local market surveillance bodies, fake fertilizer manufacturers use many different techniques to cheat customers, including the use of formulas that differ from what is printed on
the package and imitating established market brands.

Without appropriate restoration of the organic and mineral content of depleted soils, farmers often clear new land, contributing to the global deforestation problem. By improving
the quality of arable land, farmers can turn less to deforestation, which represents as much as 30% of global greenhouse emissions. Africa, with a huge agricultural potential, uses
less than 15 kgs of fertilizer per hectare, only a tenth of the global average. As a result, 75 percent of African soils are degraded, costing the continent $4 billion per year. FAO
(Food and Agricultural Organization of the United Nations) forecasts the global fertilizer demand to be 199 million metric tons in 2019.

Our Market Response

On August 8, 2017, we announced the introduction of our molecular tag to the fertilizer industry in co-operation with Rosier S.A. (“Rosier”), a mineral fertilizer manufacturer based
in Moustier, Belgium. Rosier sells high quality mineral fertilizers globally, and in Europe, through its exclusive distributor, Borealis L.A.T. Together with Rosier we launched a pilot
to DNA-tag fertilizer pellets in order to detect the dilution of genuine fertilizer with sub-standard material within a given batch, and to be able to trace the batch to its original
manufacturing location. Since the initiation of this study, we, in partnership with Rosier, have effectively marked fertilizer pellets and have successfully authenticated and detected
the dilution of fertilizer with unmarked material in a variety of laboratory and in-field tests over a nine-month period. A marked shipment of fertilizer has travelled through the supply
chain in West Africa and pellets have been analyzed in the field utilizing our in-field DNA detection technology (SigNify® IF) to provide definitive real-time authentication of the
SigNature DNA molecular tags, ensuring that the fertilizer had not been adulterated with unmarked material. The pellets tested were proven to be genuine and demonstration of the
technology gained further support for the use of molecular taggants to combat counterfeiting and to aid the many countries that are affected by adulterated fertilizer. During fiscal
2018 we had our first commercial shipment of concentrate to tag fertilizer.

During October 2018, we signed a statement of work with a life sciences company to conduct a feasibility evaluation for the tagging and authentication of seeds. In prior years, we
have performed feasibility studies for the authenticity and detection of crop protection materials supporting this market. The learnings from these proofs of concept and the
fertilizer solution create a foundation upon which a future market may be built as adjacent to our natural textiles businesses.

Future Markets:

Nucleic Acid-Based Therapeutics

Nucleic acid-based drugs and biologics have emerged as a new class of treatments for unmet medical needs. Under LRx, we are currently pursuing three types of nucleic acid-
based therapeutic applications for PCR-produced DNA: (i) adoptive cell therapy; (ii) DNA vaccines; and (iii) RNA-based therapeutics. To date, the most prominent use of adoptive
cell therapy is for CAR T-cell immuno-oncology therapies, wherein autologous or allogeneic cells are collected and genetically modified to kill cancer cells. Two CAR T-cell
therapies have recently been approved by the FDA for treatment of B-cell malignancies. These approved therapies have demonstrated high efficacy in published studies. The CAR
T-cell market is undergoing rapid growth, with over $20 billion in recent M&A activity (January 2018, Juno Therapeutics acquired by Celgene for $9 billion; August 2017, Kite
Pharma acquired by Gilead Sciences for $11.9 billion). Current CAR T-cell therapies are manufactured via bacterial plasmid and viral vector based methods. These manufacturing
methods are extremely expensive, time-consuming and may have public health concerns. We believe that production of CAR T-cell therapies via a PCR-based platform, without
plasmid or viral vectors, may lead to reduced manufacturing times, reduced costs and mitigation of public health concern.

DNA vaccines may we believe hold numerous advantages over conventional vaccination methods. DNA vaccines are able to trigger a wide range of immune responses, leading to
broad applications. DNA vaccines we believe are cheaper and easier to manufacture when compared to convention vaccines. Current DNA vaccines are manufactured via bacterial
plasmids. Production via our PCR-based platform may reduce DNA vaccine costs and manufacturing timeframes.

15

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
There are two types of RNA therapeutics. mRNA-based therapeutics, which result in protein production, and antisense/interfering RNA-based therapeutics, which interfere with or
inhibit gene expression. This dual functionality allows RNA-based therapeutics to target a wide range of indications. RNA-based therapeutics are typically manufactured from a
DNA template obtained from a bacterial plasmid. We believe creating RNA-based therapeutics from a DNA template obtained from our PCR-based platform may reduce RNA-based
therapeutic costs and manufacturing timeframes.

Our Market Response

During September 2018, we formed a new, wholly owned subsidiary LineaRx, Inc. (LRx) to develop and commercialize our extensive experience in the design, manufacture and
chemical modification of DNA via large scale PCR-based production systems in the fields of nucleic acid-based therapeutics, including drugs and biologics. We believe our PCR-
produced linear DNA products and services are made cleaner and faster than historical manufacturing methods. We are also engaged in preclinical and animal drug candidate
development, directly and with collaborators focusing on therapeutically relevant DNA constructs manufactured via our PCR-based production platform. We seek to develop,
acquire and commercialize, previously alone and now along with partners, a diverse portfolio of nucleic acid-based therapeutics based on PCR-produced linear DNA to improve
existing nucleic acid-based therapeutics or to create new nucleic acid-based therapeutics that address unmet medical needs.

Also, in September 2018, LRx signed a Joint Development Agreement with Takis S.R.L. and Evvivax S.R.L. (Takis/Evvivax) to develop PCR-produced DNA expression vectors for
two of Takis/Evvivax’s DNA-based anti-cancer vaccine candidates. Under the Joint Development Agreement, PCR-produced-linear DNA amplicons carrying the DNA sequences
for Takis/Evvivax vaccine candidates will be delivered to preclinical and animal models via Takis/Evvivax’s proprietary electroporation technology. Antigen-specific immune
responses aimed at achieving therapeutic effects will be studied. See “Collaboration and Licensing Agreements.”

On October 16, 2018 we announced that LRx entered into an exclusive licensing and research services agreement with iCell Gene Therapeutics, Inc. (“iCell”) under which LRx
licensed iCell’s anti-CD19 CAR T-cell immuno-oncology therapy canddiate for B-cell malignancies. LRx will develop the in-licensed anti-CD19 CAR T-cell immuno-oncology
therapy under a PCR-based, plasmid and viral free manufacturing platform. See “Collaboration and Licensing Agreements.”

Sales and Marketing

We have nine employees engaged in sales and marketing, of which six are directly involved with sales.

Research and Development

Our research and development efforts are primarily focused on incorporating DNA molecular tags into carriers (such as ink or textiles and more recently the incorporation of DNA
into the body of materials such as thermoplastics) and then authenticating DNA obtained from those marked products both in our laboratories and in the field, with the
development of portable infield DNA readers. As part of this effort, we typically conduct feasibility and pilot testing to ensure that DNA tagging methods are compatible with the
customer’s manufacturing and logistic processes, and that they can be implemented in a cost-effective manner. In some cases, the DNA incorporation methods may undergo wash-
out and/or adherence tests to ensure that DNA can be authenticated on a product even if it is subjected to aggressive processing techniques. We are also actively involved in
developing new DNA formulations and new methods to incorporate those new DNA formulations into products, to provide for better adhesion of DNA onto surfaces and when
appropriate, better blending of the DNA into the body of a product material. In short, we have considerable experience working with a wide range of carriers and substrates, and
authenticating them even years after they have been applied onto the surface or inside of product materials. We believe that our continued development of new and enhanced
technologies relating to our core business is essential to our future success. We incurred approximately $2.8 million and $2.3 million on research and development activities for the
fiscal years ended September 30, 2018 and 2017, respectively.

Under LRx, our research and development efforts are focused on the development of linear DNA expression vectors for use in nucleic acid-based medicines including drugs and
biologics and associated methods of linear vector manufacture. Methods for viral free transfection, high-level cellular expression and episomal persistence of linear DNA
expression vectors are under development. In addition, we are developing PCR producible linear DNA expression vectors for our anti-CD19 CAR T-cell immuno-oncology therapy
candidate licensed from iCell, as well as several cancer vaccine candidates in collaboration with Takis/Evvivax. 

Raw Materials and Suppliers

Our sources of raw materials include sources of DNA that are readily available in nature, which we are able to replicate to use in our product offerings.

Manufacturing

We have the capability to manufacture SigNature DNA molecular tags and all of our products at our laboratories in Stony Brook. We also have in-house capabilities to complete all
authentications. We are also engaged in the large-scale production of specific DNA sequences using PCR.

16

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Distribution of our Products and Commercial Agreements

Our products are distributed in the following ways:

·

·

·

directly to the customer;

through channel partners; and

through licensed distributors.

We have entered into the following agreements and arrangements for the distribution of our products, among others:

DLA. On November 13, 2014, we were awarded a contract by DLA to provide DLA with SigNature DNA molecular tags and related equipment, services and training. Beginning on
December 15, 2014, DLA’s Electronic Test Laboratory in Columbus, Ohio began DNA marking all FSC 5962 microcircuits. This created a centralized, streamlined DNA marking
process within DLA. This contract was extended through October 13, 2018. An additional follow-on two-year contract (plus one exercise year) to ensure there is no lapse in
support of the current DNA program at DLA’s PTC was signed on September 6, 2018.

Office of the Secretary of Defense. On June 6, 2017, we were awarded a two-year, approximately $1.5 million competitive-bid development contract. The award, funded by the Office
of the Secretary of Defense on behalf of the DLA, runs from June 1, 2017 to May 31 2019, and was granted via a Rapid Innovation Fund (RIF) that provides DLA with innovative
technologies that can be rapidly inserted into acquisition programs to meet specific defense needs. Management oversight for this RIF contract has been from DLA HQ located in
Fort Belvoir, Virginia. This firm-fixed price contract follows our prior RIF contract, which expired during August 2016, that enabled us to develop counterfeit mitigation technologies
based upon our proprietary DNA platforms, that protect plastics, silicone elastomers, oils, bearings, fasteners and many other high-risk commodities that are procured by DLA on
behalf of DoD. This contract will extend our authentication platform to facilitate broader use in protecting high-risk or mission-critical material purchased by DLA.

Himatsingka America. In June 2017, we announced that we had entered into a new licensing agreement with Himatsingka America, Inc., which is part of the Himatsingka Group
(“Himatsingka America”), a leading supplier of home textiles. This agreement terminates an earlier licensing agreement dated March 25, 2015 between Divatex Home Fashion, Inc. (a
predecessor to Himatsingka America) and the Company. Under the terms of the Agreement, Himatsingka America will be solely responsible for promoting, marketing and selling on
a worldwide basis the Company’s technology with respect to finished and unfinished cotton products. The Agreement grants Himatsingka America an exclusive license to use our
technology in respect of cotton, subject to certain carve-outs including governmental users, non-commercial trade associations and others. The Agreement has a term that
continues until June 23, 2042, except in the case of patents, in which case the term continues with respect to a patent until such patent is no longer in effect. The Agreement also
provides that Himatsingka America will make payments for the use of our taggant technology on a net 60 basis. In addition, Himatsingka America will make royalty payments on a
quarterly basis in arrears in the event that our technology is used on non-home products. Himatsingka America is responsible for the inspection and compliance within the supply
chain.

Himatsingka America is generally required to use our technology during the term of the Agreement, subject, among other things, to their customers’ requirements. We will be
required by the agreement to establish an independent testing laboratory in Ahmedabad, India. Finished product made from this tagged fiber will be offered for sale under the
PimaCott®, HomeGrown® LoneStar™ and HomeGrown Acala™ content-branded labels.

GHCL Limited. On June 28, 2017, we signed a multi-year license agreement with GHCL Limited (“GHCL”), a global manufacturer of home textiles, to
provide CertainT platform services in connection with source-verified, polyethylene terephthalate (PET) and recycled PET (rPET post-consumer) in select home textile products.
PET is the clear plastic best known for its use in water bottles, and is the most widely recycled plastic in the world. GHCL will use our CertainT platform in connection with PET
and/or recycled PET blended bed sheets, pillowcases, and shams products sold in-store or online in the United States. GHCL has also licensed our CertainT trademark for use on
its products, as well as for promotional, marketing and sales materials. The agreement provides for guaranteed minimum annual revenues in order to maintain exclusivity during the
renewal period, as well as trademark licensing royalties to us. GHCL will use our CertainT platform for verifying PET and recycled PET authenticity from source to retail shelf. With
this platform, we believe that GHCL is assured that any of its textile products using PET and recycled PET will contain the original source raw materials. We will provide our
patented and proprietary tagging, testing and tracking services to GHCL as a CertainT licensee. As part of the platform, our molecular tag is extruded into recycled components
that create recycled PET fiber, with no impact to performance or quality of the fiber or filament yarns. Thereafter, any piece of CertainT-tagged textiles can be forensically
authenticated by detecting the molecular tag in the recycled PET fiber, ensuring its authenticity and origin.

Loftex Home. On July 11, 2017 we signed a new multi-year exclusive license agreement with Loftex Home, LLC (“Loftex”), a manufacturer of high-quality towels and home textiles.
Under a prior agreement entered into during March 2017, we agreed to provide our CertainT™ platform services to Loftex to verify the authenticity and origin of rPET (post-
consumer) used in bath and beach towels. This new multi-year agreement between the two companies is now exclusive for bath and beach towels in the United States, non-
exclusive for plush throws and bath rugs, and provides for long term guaranteed minimum annual revenues, in order to maintain exclusivity, as well as trademark licensing royalties
to us.

American & Efird (A&E). During April 2018, we entered into a statement of work with American & Efird (A&E), one of the world’s leading manufacturers and distributors of
industrial and consumer sewing thread, embroidery thread, and technical textiles, to evaluate our Beacon® technology for use in CertainT® enchanced secure sewing threads for
brand protection. A prior statement of work dated July 25, 2017 between Applied DNA and A&E demonstrated Applied DNA’s SigNature®T DNA-based authentication. This
collaboration with A&E represents execution on the Company’s growth strategy to expand its base of business in its core markets and broaden the application of it molecular
tagging technology platform in adjacent markets.

BLC Leather Technology Center Limited (BLC). During May 2018, we completed a one-year research project with BLC under a sponsored research agreement we entered into in
March 2017 for the development of a DNA based supply chain track and trace system. The results of the research project helped validate that our technology can be used in the
harsh leather-production environment to provide forensic traceability for leather from farm to shop. In November 2018, we entered a follow-on collaboration agreement with BLC to
facilitate the commercialization of such technology. Under the terms of the collaboration agreement, we and BLC agree to jointly develop business and marketing plans, with BLC
receiving a share of the revenue we receive relating to the DNA-based tracking system. The agreement expires in November 2023.

17

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Videojet. During September 2017, we entered into a strategic partnership with Videojet Technologies Inc. (“Videojet”). We have collaborated with Videojet in the design of co-
branded SigNature® molecular-tagged Videojet inks, and a co-branded printer that electronically restricts the use of ink cartridges to only those that contain SigNature molecular
tagged inks. The relationship brings the potential to empower the tagging of countless commercial items, all of which are candidates for a CertainT licensing agreement, enabling
traceability along the entire supply chain. On October 5, 2018, this agreement was renewed for an additional one-year term.

TheraCann International. During January 2018, we entered into an initial two-year $1 million contract for the development of molecular tracking systems for legal cannabis
worldwide with TheraCann International Benchmark Corporation, (“TheraCann”), a leading full service cannabis consultancy with operations in the US, Canada, Australia, Europe
and South America, for the integration of the Company’s SigNature® molecular tagging and testing technology into TheraCann’s seed-to-sale Enterprise Resource Platform (ERP)
for legal cannabis operations. Under the terms of the contract, the companies have entered into a development and marketing agreement whereby we will develop the technologies
necessary to tag and authenticate legal cannabis throughout the supply chain and seamlessly integrate tagging and authentication data into TheraCann’s ERP and Blockchain
platform.

Colorcon, Inc. On March 31, 2018, we entered into definitive licensing and cooperation agreement as well as a related supply agreement with Colorcon, Inc. (“Colorcon”) for
molecular tagging in the pharmaceutical and nutraceutical markets. Colorcon plans to use our SigNature molecular tags in Colorcon’s product offerings and access to our
associated authentication technologies. These Agreements follow the memorandum of understanding (MOU) announced on December 18, 2017.

Under the terms of the Agreements, Applied DNA grants Colorcon exclusive worldwide right to use the Company’s molecular tags and associated authentication technologies in
film coatings for solid oral dosage form (“SOD”) applications, for which Colorcon is the largest global supplier, and non-exclusive rights to use our technologies in inks and
colorants for SOD applications. Pursuant to the Agreements, we will supply taggant and authentication materials to Colorcon in exchange for long-term royalties on the sale of
Colorcon products incorporating the Company’s molecular tags and on the sale of authentication services related thereto. Further, the first of two milestone payments was payable
to us with the signing of the Agreements. We will receive the second milestone payment upon initial approval by a regulatory authority for application in a SOD pharmaceutical or
nutraceutical product application. The Agreements generally expire on the later of October 1, 2032 or the last expiration date of any patent licensed pursuant to the Agreements.

ACG Associated Capsules Private Limited (ACG). During January 2018, we entered into a Memorandum of Understanding with ACG to develop SigNature® molecularly tagged
empty hard-shell capsules to enhance product traceability and authentication. ACG is one of the world’s largest pharmaceutical and nutraceutical capsule manufacturers, with the
empty capsules market estimated to exceed $2 billion by 2023. Discussions between us and ACG toward a definitive agreement incorporating are underway, although no assurance
can be given that a definitive agreement will be entered into.

18

 
 
 
 
 
 
 
 
 
Collaboration and Licensing Agreements

Takis S.R.L. and Evvivax S.R.L. During September 2018 we signed a joint development agreement with Takis S.R.I. and Evvivax S.R.L. (“Takis/Evvivax”), biotechnology companies
focused on the discovery and development of DNA based anti-cancer vaccines for the human and animal targets, respectively. Under the terms of the agreement, we will jointly
develop linear DNA expression vectors for two of Takis/Evvivax’s anti-cancer vaccines candidates utilizing our linear DNA technology. Linear DNA amplicons carrying the DNA
sequences for Takis/Evvivax’s vaccine candidates will be delivered to preclinical animal models via Takis/Evvivax’s proprietary electroporation technology. Antigen-specific
immune responses aimed at achieving therapeutic effects will be studied.

iCell Gene Therapeutics, Inc. During October 2018, we entered into an exclusive North American licensing agreement and research services agreement with iCell Gene
Therapeutics, Inc. (“iCell”) under which iCell licensed to us an anti-CD19 CAR T therapy candidate for non-viral delivery. We intend to utilize our non-viral, plasmid free platform,
along with the in-licensed anti-CD19 CAR T therapy to develop, manufacture and commercialize LinCART19, a non-viral, plasmid free anti-CD19 CAR T therapeutic candidate.
Under the terms of the agreements, iCell will receive a percentage of net sales derived from products incorporating the licensed CD 19 Antigen Receptor within North America, as
well as development milestone payments and a fundraising milestone. The development milestone payments are triggered up on the completion of defined phases of clinical
research for a product candidate incorporating the CD 19 Antigen Receptor. The fundraising milestone payment is triggered by an initial funding event of LRx.

Everledger, Inc. During December 2018, we entered into a Joint Development Agreement with Everledger, Inc. (Everledger), an independent emerging technology enterprise. We
intend to develop and market a combined physical and digital supply chain traceability and certification solution utilizing the our CertainT molecular tagging and authentication
systems together with Everledger’s blockchain-based platform.

Customer Concentration

Our revenues earned from sale of products and services for the fiscal year ended September 30, 2018 includes 24%, 16%, 14% and 11%, respectively from four customers. These
four customers accounted for approximately 96% of our total accounts receivable at September 30, 2018. At September 30, 2018, one customer accounted for 82% of our accounts
receivable. Our revenues earned from sale of products and services for the fiscal year ended September 30, 2017 included 29%, 26%, 13% and 10%, respectively from four
customers. These four customers accounted for approximately 97% of our total accounts receivable at September 30, 2017. At September 30, 2017, one customer accounted for an
aggregate of 80% of our total accounts receivable. Generally, our customers do not have an obligation to make purchases from us and may stop ordering our products and services
or may terminate existing orders or contracts at any time with little or no financial penalty. The loss of any of our significant customers, any substantial decline in sales to these
customers, or any significant change in the timing or volume of purchases by our customers, could result in lower revenues and could harm our business, financial condition or
results of operations.

Competition

The principal markets for our offerings are intensely competitive. We compete with many existing suppliers and new competitors continue to enter the market. Many of our
competitors, both in the United States and elsewhere, are major pharmaceutical, chemical and biotechnology companies, or have strategic alliances with such companies, and many
of them have substantially greater capital resources, marketing experience, research and development staff, and facilities than we do. Any of these companies could succeed in
developing products that are more effective than the products that we have or may develop and may be more successful than us in producing and marketing their existing
products. Some of our competitors that operate in the anti-counterfeiting and fraud prevention markets include: 3DTL Inc., Alp Vision Sa, Authentix Inc., Brandwatch
Technologies, Chromologic LLC, Collectors Universe Inc., Collotype Labels International, Data Dot Technology, De La Rue Plc., Digimarc Corp., DNA Technologies, Inc., DuPont
Authentication Systems, FractureCode Corporation, Haelixa, ICA Bremen GmbH, ID Global Solutions Corporation, IEH Corporation Informium AG, Eastman Kodak Company, L-1
Identity Solutions Inc., opSec Security Group plc., MicroTagTemed Ltd., Nanotech Security Corp., Nokomis, Inc., Oritain Global Limited, ProoftagSAS, SafeTraces Inc., Selectamark
Security Systems plc, Spectra Systems Corp., SmartWater Technology, Inc., Sun Chemical Corp, TraceTag International, TruTag Technologies Inc., YottaMark Inc., and Safe
Traces, Inc.  Some of our competitors that operate in the biotechnology markets include: Intrexon Corp,. Aldervron, LLC, Cobra Biologics, Limited, Integrated DNA Technologies,
Inc., Ziopharm Oncology, Inc., MaxCyte Inc. and Touchlight Genetics Ltd. 

Some examples of competing security products include:

·

·

·

·

integrated circuit chip and magnetic strips (integrated circuit chips that receive and, if authentic, send a correct electric signal back to the reader, and magnetic strips that
contain information, both of which are common components of debit and credit cards);

optically variable microstructures (these include holograms, which display images in three dimensions and are generally difficult to reproduce using advanced color
photocopiers and printing techniques, along with other devices with similar features);

elemental taggants and fluorescence (elemental taggants are various unique substances that can be used to mark products and other items, and are revealed by
techniques such as x-ray fluorescence); and

radioactivity and rare molecules (radioactive substances or rare molecules which are uncommon and readily detected).

We expect competition with our products and services to continue and intensify in the future. We believe competition in our principal markets is primarily driven by:

·

·

product performance, features and liability;

price;

19

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
·

·

·

·

·

·

·

timing of product introductions;

ability to develop, maintain and protect proprietary products and technologies;

sales and distribution capabilities;

technical support and service;

brand loyalty;

applications support; and

breadth of product line.

If a competitor develops superior technology or cost-effective alternatives to our products, our business, financial condition and results of operations could be significantly
harmed.

Proprietary Rights

We believe that our approximately 75 patents, 53 patent applications, 48 trademark registrations, and 5 trademark applications, and our trade secrets, copyrights and other
intellectual property rights are important assets for us. Our patents will expire at various times between 2021 and 2033. The duration of our trademark registrations varies from
country to country. However, trademarks are generally valid and may be renewed indefinitely as long as they are in use and/or their registrations are properly maintained.

On May 31, 2017, 3SI granted a non-exclusive license to us to exploit, including the rights to have manufactured and have assembled and offer for sale, sell, market, advertise and
distribute nucleic acid tags suitable for use in any product or system covered by one or more valid claims in any unexpired patents worldwide. On September 11, 2015, as part of the
Vandalia Asset Acquisition, Marshall University Research Corporation consented to the assignment and transfer of Vandalia’s exclusive worldwide right and license under patents
to manufacture, use, produce, sell and have sold, market and develop the Triathlon DNA production system or derivatives therefrom to us.

On October 12, 2018, iCell Gene Therapeutics, Inc. granted us an exclusive North America license to make, have made, use, offer to sell, sell and important its anti-CD19 CAR T-cell
immuno-oncology therapeutic candidate in the field of non-virally mediated transfection of non-plasmid derived DNA. See “Collaboration and Licensing Agreements.”

However, there are events that are outside of our control that pose a threat to our intellectual property rights as well as to our products and services. For example, effective
intellectual property protection may not be available in every country in which our products and services are distributed. The efforts we have taken to protect our proprietary
rights may not be sufficient or effective. Any significant impairment of our intellectual property rights could harm our business or our ability to compete. Protecting our intellectual
property rights is costly and time consuming. Any increase in the unauthorized use of our intellectual property could make it more expensive to do business and harm our
operating results. Although we seek to obtain patent protection for our innovations, it is possible we may not be able to protect some of these innovations. Given the costs of
obtaining patent protection, we may choose not to protect certain innovations that later turn out to be important. There is always the possibility that the scope of the protection
gained from one of our issued patents will be insufficient or deemed invalid or unenforceable. We also seek to maintain certain intellectual property as trade secrets. This secrecy
could be compromised by third parties, or intentionally or accidentally by our employees, which would cause us to lose the competitive advantage resulting from these trade
secrets.

Litigation regarding patents and other intellectual property rights is extensive in the biotechnology industry. In the event of an intellectual property dispute, we may be forced to
litigate. This litigation could involve proceedings instituted by the U.S. Patent and Trademark Office or the International Trade Commission, as well as proceedings brought directly
by affected third parties. Intellectual property litigation can be extremely expensive, and these expenses, as well as the consequences should we not prevail, could seriously harm
our business. If a third party claims an intellectual property right to technology we use, we might need to discontinue an important product or product line, alter our products and
processes, pay license fees or cease our affected business activities. Although we might under these circumstances attempt to obtain a license to this intellectual property, we may
not be able to do so on favorable terms, or at all.

20

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Government Approvals of Commercial Products

We do not require any governmental approvals of our currently commercialized products or services.

Government Approvals of Drug and Biologic Products

Some of our products may be incorporated into drug and biologic products which are subject to extensive regulation by FDA and other regulatory agencies in the United States
and by comparable authorities in foreign countries. Biologics include a wide range of products such as vaccines, gene therapy, and recombinant therapeutic proteins. Biologics
can be composed of sugars, proteins or nucleic acids or complex combinations of these substances. They may also be living entities such as cells or tissue. Our products that are
incorporated into drugs and biologics will be subject to regulation as described in the next section. Some of our products may be drugs or biologics that are subjected to regulation
as described in the following section. In either case, we are unlikely to receive material revenues until the related drug or biologic receives regulatory approval. The FDA and other
authorities regulate among other things, the research, development, testing, manufacture, storage, recordkeeping, approval, labeling, promotion and marketing, distribution, post-
approval monitoring and reporting, sampling and import and export of drug and biologic products. Failure to comply with applicable U.S. requirements may subject a company to a
variety of administrative or judicial sanctions, such as FDA refusal to file a marketing application, to issue Complete Response letter or to not approve pending New Drug
Applications (“NDAs”) or biologic product license applications (“BLAs”), or to issue warning letters, product recalls, product seizures, total or partial suspension of production or
distribution, injunctions, fines, civil penalties, litigation, government investigation and criminal prosecution.

Drug and biologic products that must undergo preclinical and clinical evaluation relating to product safety and efficacy before they are approved as commercial therapeutics
products. The regulatory authorities having jurisdiction in the countries in which our collaborators and customers intend to market their products may delay or put on hold clinical
trials, delay approval of a product or determine that the product is not approvable. The FDA and comparable government authorities having jurisdiction in the countries in which
our customers intend to market their products have the authority to withdraw product approval or suspend manufacture if there are significant problems with raw materials or
supplies, quality control and assurance, safety, efficacy or the product is deemed adulterated or misbranded.

Government Regulation of Pharmaceutical and Biologic Products

In the United States, the FDA regulates drugs and biologics under the Federal Food, Drug, and Cosmetic Act, or FDCA, and its implementing regulations. The process of obtaining
regulatory approvals and the subsequent compliance with applicable federal, state, local and foreign statutes and regulations requires the expenditure of substantial time and
financial resources. Failure to comply with the applicable U.S. requirements at any time during the product development process, approval process or after approval, may subject
an applicant to a variety of administrative or judicial sanctions, such as the FDA’s refusal to approve pending NDAs or BLAs, withdrawal of an approval, imposition of a clinical
hold, issuance of warning letters, product recalls, product seizures, total or partial suspension of production or distribution, injunctions, fines, refusals of government contracts,
restitution, disgorgement or civil or criminal penalties.

The process required by the FDA before a drug or biologic may be marketed in the United States generally involves the following:

•

•

•

•

•

•

•

•

•

•

completion of preclinical laboratory tests, animal studies and formulation studies in compliance with the FDA’s Good Laboratory Practice (“GLP”) regulations;

submission to the FDA of an Investigational New Drug Application (“IND”), which must become effective before human clinical trials may begin;

approval by an independent Institutional Review Board (“IRB”) at each clinical site before each trial may be initiated;

performance of adequate and well-controlled human clinical trials in accordance with Current Good Clinical Practices (“cGCPs”), requirements to establish the safety
and efficacy of the proposed drug or biologic product for each indication;

submission to the FDA of an NDA or BLA;

satisfactory completion of an FDA advisory committee review, if applicable;

satisfactory completion of an FDA inspection of the manufacturing facility or facilities at which the drug or biologic product is produced to assess compliance with
current good manufacturing practice (“GMP”) requirements and to assure that the facilities, methods and controls are adequate to preserve the drug’s identity,
strength, quality and purity;

satisfactory completion of FDA audits of clinical trial sites to assure compliance with cGCPs and the integrity of the clinical data;

payment of user fees and securing FDA approval of the NDA or BLA; and

compliance with any post-approval requirements, including the potential requirement to implement a Risk Evaluation and Mitigation Strategy (“REMS”), and the
potential requirement to conduct post-approval studies.

Preclinical Studies

Preclinical studies include laboratory evaluation of product chemistry, toxicity and formulation, as well as animal studies to assess potential safety and efficacy. An IND sponsor
must submit the results of the preclinical tests, together with manufacturing information, analytical data and any available clinical data or literature, among other things, to the FDA
as part of an IND. Some preclinical testing may continue even after the IND is submitted. An IND automatically becomes effective 30 days after receipt by the FDA, unless before
that time the FDA raises concerns or questions related to one or more proposed clinical trials and places the clinical trial on a clinical hold. In such a case, the IND sponsor and the
FDA must resolve any outstanding concerns before the clinical trial can begin. As a result, submission of an IND may not result in the FDA allowing clinical trials to initiate.

21

 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Clinical Trials

Clinical trials involve the administration of the investigational new drug or biologic product to human subjects under the supervision of qualified investigators in accordance with
cGCP requirements, which include the requirement that all research subjects provide their informed consent in writing for their participation in any clinical trial. Clinical trials are
conducted under protocols detailing, among other things, the objectives of the trial, the parameters to be used in monitoring safety, and the effectiveness criteria to be evaluated.
A protocol for each clinical trial and any subsequent protocol amendments must be submitted to the FDA. In addition, an IRB at each institution participating in the clinical trial
must review and approve the plan for any clinical trial before it initiates at that institution. Information about certain clinical trials must be submitted within specific timeframes to
the National Institutes of Health, or NIH, for public dissemination on their www.clinicaltrials.gov website.

Human clinical trials are typically conducted in three sequential phases, which may overlap or be combined:

•

•

•

Phase 1: The drug or biologic is initially introduced into healthy human subjects or patients with the target disease or condition and tested for safety, dosage
tolerance, absorption, metabolism, distribution, excretion and, if possible, to gain an early indication of its effectiveness.

Phase 2: The drug or biologic is administered to a limited patient population to identify possible adverse effects and safety risks, to preliminarily evaluate the efficacy
of the product for specific targeted diseases and to determine dosage tolerance and optimal dosage.

Phase 3: The drug or biologic is administered to an expanded patient population, generally at geographically dispersed clinical trial sites, in well-controlled clinical
trials to generate enough data to statistically evaluate the efficacy and safety of the product for approval, to establish the overall risk-benefit profile of the product,
and to provide adequate information for the labeling of the product.

Progress reports detailing the results of the clinical trials must be submitted at least annually to the FDA and more frequently if serious adverse events occur. Phase 1, Phase 2 and
Phase 3 trials may not be completed successfully within any specified period, or at all. Furthermore, the FDA or the sponsor may suspend or terminate a clinical trial at any time on
various grounds, including a finding that the research subjects are being exposed to an unacceptable health risk. Similarly, an IRB can suspend or terminate approval of a clinical
trial at its institution if the clinical trial is not being conducted in accordance with the IRB’s requirements or if the drug or biologic has been associated with unexpected serious
harm to patients.

Marketing Approval

Assuming successful completion of the required clinical testing, the results of the preclinical and clinical studies, together with detailed information relating to the product’s
chemistry, manufacture, controls and proposed labeling, among other things, are submitted to the FDA as part of an NDA or BLA requesting approval to market the product for
one or more indications. In most cases, the submission of an NDA or BLA is subject to a substantial application user fee. Under the Prescription Drug User Fee Act, or PDUFA,
guidelines that are currently in effect, the FDA has a goal of ten months from the date of “filing” of a standard NDA or BLA, for a new molecular entity to review and act on the
submission. This review typically takes twelve months from the date the NDA or BLA is submitted to FDA because the FDA has approximately two months to make a “filing”
decision.

The FDA also may require submission of a REMS plan to ensure that the benefits of the drug or biologic outweigh its risks. The REMS plan could include medication guides,
physician communication plans, assessment plans, and/or elements to assure safe use, such as restricted distribution methods, patient registries, or other risk minimization tools.

The FDA conducts a preliminary review of all NDAs or BLA within the first 60 days after submission, before accepting them for filing, to determine whether they are sufficiently
complete to permit substantive review. The FDA may request additional information rather than accept an NDA or BLA for filing. In this event, the application must be resubmitted
with the additional information. The resubmitted application is also subject to review before the FDA accepts it for filing. Once the submission is accepted for filing, the FDA
begins an in-depth substantive review. The FDA reviews an NDA or BLA to determine, among other things, whether the drug or biologic is safe and effective and whether the
facility in which it is manufactured, processed, packaged or held meets standards designed to assure the product’s continued safety, quality and purity.

The FDA may refer an application for a novel drug or biologic to an advisory committee. An advisory committee is a panel of independent experts, including clinicians and other
scientific experts, which reviews, evaluates and provides a recommendation as to whether the application should be approved and under what conditions. The FDA is not bound
by the recommendations of an advisory committee, but it considers such recommendations carefully when making decisions.

22

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Before approving an NDA or BLA, the FDA typically will inspect the facility or facilities where the product is manufactured. The FDA will not approve an application unless it
determines that the manufacturing processes and facilities are in compliance with cGMP requirements and adequate to assure consistent production of the product within required
specifications. Additionally, before approving an NDA or BLA, the FDA may inspect one or more clinical trial sites to assure compliance with cGCP requirements.

After evaluating the NDA or BLA and all related information, including the advisory committee recommendation, if any, and inspection reports regarding the manufacturing
facilities and clinical trial sites, the FDA may issue an approval letter, or, in some cases, a complete response letter. A complete response letter generally contains a statement of
specific conditions that must be met in order to secure final approval of the NDA or BLA and may require additional clinical or preclinical testing in order for FDA to reconsider the
application. Even with submission of this additional information, the FDA ultimately may decide that the application does not satisfy the regulatory criteria for approval. If and
when those conditions have been met to the FDA’s satisfaction, the FDA will typically issue an approval letter. An approval letter authorizes commercial marketing of the drug
with specific prescribing information for specific indications.

Even if the FDA approves a product, it may limit the approved indications for use of the product, require that contraindications, warnings or precautions be included in the product
labeling, require that post-approval studies, including Phase 4 clinical trials, be conducted to further assess a drug or biologic’s safety after approval, require testing and
surveillance programs to monitor the product after commercialization, or impose other conditions, including distribution and use restrictions or other risk management mechanisms
under a REMS, which can materially affect the potential market and profitability of the product. The FDA may prevent or limit further marketing of a product based on the results of
post-marketing studies or surveillance programs. After approval, some types of changes to the approved product, such as adding new indications, manufacturing changes, and
additional labeling claims, are subject to further testing requirements and FDA review and approval.

Post-Approval Requirements

Drugs or biologics manufactured or distributed pursuant to FDA approvals are subject to pervasive and continuing regulation by the FDA, including, among other things,
requirements relating to recordkeeping, periodic reporting, product sampling and distribution, advertising and promotion and reporting of adverse experiences with the product.
After approval, most changes to the approved product, such as adding new indications or other labeling claims are subject to prior FDA review and approval. There are
continuing, annual user fee requirements for any marketed products and the establishments where such products are manufactured, as well as new application fees for
supplemental applications with clinical data.

The FDA may impose a number of post-approval requirements as a condition of approval of an NDA or BLA. For example, the FDA may require post-marketing testing, including
Phase 4 clinical trials, and surveillance to further assess and monitor the product’s safety and effectiveness after commercialization.

In addition, drug and biologic manufacturers and other entities involved in the manufacture and distribution of approved drugs or biologics are required to register their
establishments with the FDA and state agencies and are subject to periodic unannounced inspections by the FDA and these state agencies for compliance with cGMP
requirements. Changes to the manufacturing process are strictly regulated and often require prior FDA approval before being implemented. FDA regulations also require
investigation and correction of any deviations from cGMP requirements and impose reporting and documentation requirements upon the sponsor and any third-party
manufacturers that the sponsor may decide to use. Accordingly, manufacturers must continue to expend time, money, and effort in the area of production and quality control to
maintain cGMP compliance.

Once an approval of a drug or biologic is granted, the FDA may withdraw the approval if compliance with regulatory requirements and standards is not maintained or if problems
occur after the product reaches the market. Later discovery of previously unknown problems with a product, including adverse events of unanticipated severity or frequency, or
with manufacturing processes, or failure to comply with regulatory requirements, may result in mandatory revisions to the approved labeling to add new safety information;
imposition of post-market studies or clinical trials to assess new safety risks; or imposition of distribution or other restrictions under a REMS program. Other potential
consequences include, among other things:

•

•

•

•

•

restrictions on the marketing or manufacturing of the product, complete withdrawal of the product from the market or product recalls;

fines, warning letters or holds on post-approval clinical trials;

refusal of the FDA to approve pending NDAs or BLAs or supplements to approved NDAs or BLAs, or suspension or revocation of product approvals;

product seizure or detention, or refusal to permit the import or export of products; and

injunctions or the imposition of civil or criminal penalties.

The FDA strictly regulates marketing, labeling, advertising and promotion of products that are placed on the market. Drugs or biologics may be promoted only for the approved
indications and in accordance with the provisions of the approved label. The FDA and other agencies actively enforce the laws and regulations prohibiting the promotion of off-
label uses, and a company that is found to have improperly promoted off-label uses may be subject to significant liability.

In many foreign countries, drugs and biologics are subject to regulatory requirements in addition to and sometimes different than the U.S. requirements described herein.

23

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
U.S. Healthcare Fraud and Abuse Laws and Compliance Requirements

We are subject to various federal and state laws targeting fraud and abuse in the healthcare industry. These laws may impact, among other things, our proposed sales and
marketing programs for drugs and biologics. In addition, we may be subject to patient privacy regulation by both the federal government and the states in which we conduct our
business. The laws that may affect such operations include:

•

•

•

•

the federal Anti-Kickback Statute, which prohibits, among other things, persons from soliciting, receiving, offering or paying remuneration, directly or indirectly, in
cash or in kind, to induce or reward, or in return for, either the referral of an individual for, or the purchase, order or recommendation of, an item or service
reimbursable under a federal healthcare program, such as the Medicare and Medicaid programs. The term “remuneration” has been broadly interpreted to include
anything of value;

federal false claims and civil monetary penalties laws, including the federal civil False Claims Act, which prohibits anyone from, among other things, knowingly
presenting, or causing to be presented, for payment to federal programs (including Medicare and Medicaid) claims for items or services that are false or fraudulent;

provisions of the federal Health Insurance Portability and Accountability Act of 1996 (“HIPAA”), which created federal criminal statutes that prohibit, among other
things, knowingly and willfully executing a scheme to defraud any healthcare benefit program or making false statements in connection with the delivery of or
payment for healthcare benefits, items or services. In addition, HIPAA, as amended by the Health Information Technology for Economic and Clinical Health Act
(“HITECH”) and its implementing regulations, impose certain requirements relating to the privacy, security and transmission of individually identifiable health
information; and

the federal Physician Payments Sunshine Act requirements, under the Patient Protection and Affordable Care Act (“ACA”), which require manufacturers of certain
drugs and biologics to track and report to Centers for Medicare & Medicaid Services, or CMS, payments and other transfers of value they make to U.S. physicians
and teaching hospitals as well as physician ownership and investment interests in the manufacturer.

Other U.S. Regulatory Matters

Manufacturing, sales, promotion and other activities following product approval for drugs and biologics are also subject to regulation by numerous regulatory authorities in the
United States in addition to the FDA, including the Centers for Medicare & Medicaid Services, other divisions of the Department of Health and Human Services, the Department of
Justice, the Drug Enforcement Administration, the Consumer Product Safety Commission, the Federal Trade Commission, the Occupational Safety & Health Administration, the
Environmental Protection Agency and state and local governments. Sales, marketing and scientific and educational programs also must comply with state and federal fraud and
abuse laws.

Pricing and rebate programs must comply with the Medicaid rebate requirements of the U.S. Omnibus Budget Reconciliation Act of 1990 and more recent requirements in the ACA.
If products are made available to authorized users of the Federal Supply Schedule of the General Services Administration, additional laws and requirements apply. Products must
meet applicable child-resistant packaging requirements under the U.S. Poison Prevention Packaging Act. Manufacturing, sales, promotion and other activities also are potentially
subject to federal and state consumer protection and unfair competition laws.

The distribution of pharmaceutical and biologic products is subject to additional requirements and regulations, including extensive record-keeping, licensing, storage and security
requirements intended to prevent the unauthorized sale of pharmaceutical products.

The failure to comply with any of these laws or regulatory requirements subjects firms to possible legal or regulatory action. Depending on the circumstances, failure to meet
applicable regulatory requirements can result in criminal prosecution, fines or other penalties, injunctions, requests for recall, seizure of products, total or partial suspension of
production, denial or withdrawal of product approvals or refusal to allow a firm to enter into supply contracts, including government contracts. Any action against us for violation
of these laws, even if we successfully defend against it, could cause us to incur significant legal expenses and divert our management’s attention from the operation of our
business. Prohibitions or restrictions on sales or withdrawal of future products marketed by us could materially affect our business in an adverse way.

Changes in regulations, statutes or the interpretation of existing regulations could impact our business in the future by requiring, for example: (i) changes to our manufacturing
arrangements; (ii) additions or modifications to product labeling; (iii) the recall or discontinuation of our products; or (iv) additional record-keeping requirements. If any such
changes were to be imposed, they could adversely affect the operation of our business.

24

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Coverage and Reimbursement

Sales of our drug and biologic products will depend, in part, on the extent to which such products will be covered by third party payors, such as government health programs,
commercial insurance and managed healthcare organizations. In the United States no uniform policy of coverage and reimbursement for drug products or biologics exists.
Accordingly, decisions regarding the extent of coverage and amount of reimbursement to be provided for any of our products will be made on a payor-by-payor basis. As a result,
the coverage determination process is often a time-consuming and costly process that will require us to provide scientific and clinical support for the use of our products to each
payor separately, with no assurance that coverage and adequate reimbursement will be obtained.

The United States government, state legislatures and foreign governments have shown significant interest in implementing cost containment programs to limit the growth of
government-paid health care costs, including price-controls, restrictions on reimbursement and requirements for substitution of generic products for branded prescription drugs or
biologics. For example, the ACA contains provisions that may reduce the profitability of drug products or biologics through increased rebates for drugs or biologics reimbursed by
Medicaid programs, extension of Medicaid rebates to Medicaid managed care plans, mandatory discounts for certain Medicare Part D beneficiaries and annual fees based on
pharmaceutical companies’ share of sales to federal health care programs. Adoption of general controls and measures, coupled with the tightening of restrictive policies in
jurisdictions with existing controls and measures, could limit payments for pharmaceutical drugs or biologics.

The Medicaid Drug Rebate Program requires pharmaceutical manufacturers to enter into and have in effect a national rebate agreement with the Secretary of the Department of
Health and Human Services as a condition for states to receive federal matching funds for the manufacturer’s outpatient drugs or biologics furnished to Medicaid patients. The
ACA made several changes to the Medicaid Drug Rebate Program, including increasing pharmaceutical manufacturers’ rebate liability by raising the minimum basic Medicaid
rebate on most branded prescription drugs from 15.1% of average manufacturer price, or AMP, to 23.1% of AMP and adding a new rebate calculation for “line extensions” (i.e., new
formulations, such as extended release formulations) of solid oral dosage forms of branded products, as well as potentially impacting their rebate liability by modifying the
statutory definition of AMP. The ACA also expanded the universe of Medicaid utilization subject to drug rebates by requiring pharmaceutical manufacturers to pay rebates on
Medicaid managed care utilization and by enlarging the population potentially eligible for Medicaid drug benefits. CMS has proposed to expand Medicaid rebate liability to the
territories of the United States as well.

The Medicare Prescription Drug, Improvement, and Modernization Act of 2003, or the MMA, established the Medicare Part D program to provide a voluntary prescription drug
benefit to Medicare beneficiaries. Under Part D, Medicare beneficiaries may enroll in prescription drug plans offered by private entities that provide coverage of outpatient
prescription drugs. Unlike Medicare Part A and B, Part D coverage is not standardized. While all Medicare drug plans must give at least a standard level of coverage set by
Medicare, Part D prescription drug plan sponsors are not required to pay for all covered Part D drugs, and each drug plan can develop its own drug formulary that identifies which
drugs it will cover and at what tier or level. However, Part D prescription drug formularies must include drugs within each therapeutic category and class of covered Part D drugs,
though not necessarily all the drugs in each category or class. Any formulary used by a Part D prescription drug plan must be developed and reviewed by a pharmacy and
therapeutic committee. Government payment for some of the costs of prescription drugs may increase demand for products for which we receive marketing approval. However, any
negotiated prices for our products covered by a Part D prescription drug plan likely will be lower than the prices we might otherwise obtain. Moreover, while the MMA applies
only to drug benefits for Medicare beneficiaries, private payors often follow Medicare coverage policy and payment limitations in setting their own payment rates. Any reduction
in payment that results from the MMA may result in a similar reduction in payments from non-governmental payors.

For a drug product to receive federal reimbursement under the Medicaid or Medicare Part B programs or to be sold directly to U.S. government agencies, the manufacturer must
extend discounts to entities eligible to participate in the 340B drug pricing program. The required 340B discount on a given product is calculated based on the AMP and Medicaid
rebate amounts reported by the manufacturer. As of 2010, the ACA expanded the types of entities eligible to receive discounted 340B pricing, although, under the current state of
the law, with the exception of children’s hospitals, these newly eligible entities will not be eligible to receive discounted 340B pricing on orphan drugs. In addition, as 340B drug
prices are determined based on AMP and Medicaid rebate data, the revisions to the Medicaid rebate formula and AMP definition described above could cause the required 340B
discount to increase.

As noted above, the marketability of any drug or biologic products for which we receive regulatory approval for commercial sale may suffer if the government and third-party
payors fail to provide adequate coverage and reimbursement. An emphasis on cost containment measures in the United States has increased, and we expect will continue to
increase, the pressure on pharmaceutical pricing. Coverage policies and third-party reimbursement rates may change at any time. Even if favorable coverage and reimbursement
status is attained for one or more products for which we receive regulatory approval, less favorable coverage policies and reimbursement rates may be implemented in the future.

In addition, in most foreign countries, the proposed pricing for a drug or biologic must be approved before it may be lawfully marketed. The requirements governing drug and
biologic pricing and reimbursement vary widely from country to country. For example, the European Union provides options for its member states to restrict the range of medicinal
products for which their national health insurance systems provide reimbursement and to control the prices of medicinal products for human use. A member state may approve a
specific price for the medicinal product or it may instead adopt a system of direct or indirect controls on the profitability of the company placing the medicinal product on the
market. There can be no assurance that any country that has price controls or reimbursement limitations for pharmaceutical products will allow favorable reimbursement and pricing
arrangements for any of our products. Historically, products launched in the European Union do not follow price structures of the United States and generally prices tend to be
significantly lower.

25

 
 
 
 
 
 
 
 
 
  
 
 
Impact of Other Government Regulation

We and our products are subject to regulation by various U.S. federal regulatory agencies such as the Federal Trade Commission and are subject to regulation by the Occupational
Safety and Health Administration (“OSHA”) concerning employee safety and health matters. Such regulations principally relate to the ingredients, labeling, packaging, advertising
and marketing of our products. There are no significant capital expenditures for government regulation matters either planned in the current year or expected in the near future.

Compliance with Environmental Law

We believe that we are in compliance with all applicable environmental law.

Employees

As of September 30, 2018 we had a total of 59 employees, consisting of 3 in management, 12 in research and development, 1 in life sciences, 5 in forensics, 6 in quality assurance
and compliance, 4 in finance and accounting, 1 in legal, 9 in operations, 9 in sales and marketing, 1 in human resources, 2 in shared services, 5 in information services, and 1 in
product development. Expenses related to travel, marketing, salaries, and general overhead will be increased as necessary to support our growth in revenue. Any projected
increase in human capital is dependent upon our ability to generate revenues and obtain sources of funding. As we continue to expand, we will incur additional costs for human
capital. Since June 2012, we have been working with Insperity Inc. to assist in managing many of our back-end administrative human resources, benefits, and payroll
responsibilities. We are an at-will employer and generally do not enter into employment agreements requiring our employees to continue in our employment for any period of time,
with the exception of our Chief Executive Officer, Dr. James A. Hayward. The initial term of Dr. Hayward’s current employment agreement is July 1, 2016 through June 30, 2017, and
this employment agreement automatically renews for one-year periods subject to ninety days’ prior notice of non-renewal by Dr. Hayward or us in accordance with the terms of the
employment agreement. As of June 30, 2018, the employment contract renewed for an additional year.

Available Information

We are subject to the informational requirements of the Exchange Act, which requires us to file our Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q, Current
Reports on Form 8-K, amendments to such reports and other information with the SEC. This information is available at the SEC’s Public Reference Room at 100 F Street, NE,
Washington, D.C. 20549. Information on the operation of the Public Reference Room can be obtained by calling the SEC at 1-800-SEC-0330. Because we file documents
electronically with the SEC, you may also obtain this information by visiting the SEC’s website at: www.sec.gov. Our website is located at: www.adnas.com. The information on, or
that may be accessed through, our website is not incorporated by reference into and should not be considered a part of this report.

ITEM 1A.

RISK FACTORS.

Because of the following factors, as well as other variables affecting our operating results and financial condition, past financial performance may not be a reliable indicator of
future performance, and historical trends should not be used to anticipate results or trends in future periods. In addition to the factors discussed elsewhere in this report and our
other reports and documents filed with the SEC, the following are important factors that could cause actual results or events to differ materially from those contained in any
forward-looking statements made by us or on our behalf. The risks and uncertainties described below are not the only ones we face. Additional risks and uncertainties not
presently known to us or that we may currently deem immaterial also may impair our business, financial condition, operating results and/or stock price. If any of the following risks
or such other risks actually occurs, our business, financial condition, operating results and/or stock price could be harmed. In the following factors, “volatility in our share price”,
“adverse impact on the price (or value) of our shares”, “decline in the price of our common stock” and similar terms also refer to our warrants and shares to be received upon
exercise of our warrants.

Risks Relating to Our Business:

There is substantial doubt relating to our ability to continue as a going concern.

We have recurring net losses, which have resulted in an accumulated deficit of $248,366,083 as of September 30, 2018. We have incurred a net loss of $11,692,928 for the fiscal year
ended September 30, 2018. At September 30, 2018, we had cash and cash equivalents of $1,659,564. We have concluded that these factors raise substantial doubt about our ability
to continue as a going concern for one year from the issuance of the financial statements.

In addition, the report from our independent registered public accounting firm for the year ended September 30, 2018 includes an explanatory paragraph stating that our significant
losses and needs to raise additional funds to meet our obligations and sustain operations raise substantial doubt about our ability to continue as a going concern. We will
continue to seek to raise additional working capital through public equity, private equity or debt financings. If we fail to raise additional working capital, or do so on commercially
unfavorable terms, it would materially and adversely affect our business, prospects, financial condition and results of operations, and we may be unable to continue as a going
concern. Future reports from our independent registered public accounting firm may also contain statements expressing substantial doubt about our ability to continue as a going
concern. If we seek additional financing to fund our business activities in the future and there remains substantial doubt about our ability to continue as a going concern, investors
or other financing sources may be unwilling to provide additional funding to us on commercially reasonable terms, if at all.

We have not produced significant revenues. This makes it difficult to evaluate our future prospects and increases the risk that we will not be successful.

Our operations since inception have produced limited revenues, and may not produce significant revenues in the near term, or at all, which may harm our ability to obtain additional
financing and may require us to reduce or discontinue our operations. If we create significant revenues in the future, we expect to derive most of such revenues from the sale of
supply chain security and product authentication solutions. You must consider our business and prospects in light of the risks and difficulties we will encounter as a company
operating in a rapidly evolving industry. We may not be able to successfully address these risks and difficulties, which could significantly harm our business, operating results,
and financial condition.

26

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
We have a history of net losses which may continue, and which may harm our ability to obtain financing and continue our operations.

We incurred net losses of $11.7 million and $12.9 million for the fiscal years ended September 30, 2018 and 2017, respectively. These net losses have principally been the result of
the various costs associated with our selling, general and administrative and research and development expenses as we expanded operations, acquired, developed and validated
technologies and expanded marketing activities. Our operations are subject to the risks and competition inherent in a company that moved from the development stage to an
operating company. We may not generate sufficient revenues from operations to achieve or sustain profitability on a quarterly, annual or any other basis in the future. Our
revenues and profits, if any, will depend upon various factors, including whether our existing products and services or any new products and services we develop will achieve
market acceptance. If we continue to incur losses, then our accumulated deficit will continue to increase which may significantly impair our ability to obtain additional financing. As
a result, our business, results of operations and financial condition would be significantly harmed, and we may be required to reduce or terminate our operations.

If we are unable to obtain additional financing our business operations may be harmed or discontinued.

Our continuation as a going concern is dependent upon our future revenues and our ability to commercialize more products, obtain additional capital and attain profitable
operations. We may require additional funds to complete the continued development and commercialization of our products, product manufacturing, and to fund expected
additional losses from operations, until revenues are sufficient to cover our operating expenses. If we are unsuccessful in obtaining any necessary additional financing, we will
most likely be forced to reduce or terminate our operations.

Our opportunities in pharmaceuticals and biologics will require substantial additional funding.  We may not be successful in our efforts to create a pipeline of product
candidates or to develop commercially successful products. If we fail to successfully identify, finance and develop product candidates, our commercial opportunities in
pharmaceuticals and biologics may be limited.

We have no pharmaceutical or biologic products approved for commercial sale and have not generated any revenue from product sales. Identifying, developing, obtaining
regulatory approval and commercializing pharmaceutical and biologic product candidates will require substantial additional funding beyond our current available resources and is
prone to the risks of failure inherent in drug or biologic development. Developing product candidates is expensive, and we expect to spend substantial amounts as we fund our
early-stage research projects, engage in preclinical development of early-stage programs and, in particular, advance program candidates through preclinical development and
clinical trials.

Even if we receive regulatory approval to market any of our product candidates, we cannot assure you that any such product candidate will be successfully commercialized, widely
accepted in the marketplace or more effective than other commercially available alternatives.

Investment in pharmaceutical and biologic product development involves significant risk that any product candidate will fail to demonstrate adequate efficacy or an acceptable
safety profile, gain regulatory approval, and become commercially viable. We cannot provide any assurance that we will be able to successfully advance any product candidates
through the development process or, if approved, successfully commercialize any product candidates.

Even if we are able to generate revenue from the sale of any approved pharmaceutical and biologic products, we may not become profitable and may need to obtain additional
funding to continue operations. Our failure to become and remain profitable would decrease the value of our company and could impair our ability to raise capital, expand our
business, maintain our research and development efforts, diversify our pipeline of product candidates or continue our operations, and cause a decline in the value of our common
stock, all or any of which may adversely affect our viability.

Our operating results could be adversely affected by a reduction in business with our significant customers.

Our revenue earned from the sale of products and services for the fiscal year ended September 30, 2018 included an aggregate of 65% of our total revenues from four customers.
These four customers accounted for approximately 96% of our total accounts receivable at September 30, 2018. At September 30, 2018, one customer accounted for an aggregate of
82% of our total accounts receivable. Our revenues earned from sale of products and services for the fiscal year ended September 30, 2017 included an aggregate of 78% from four
customers of our total revenues. These four customers accounted for approximately 97% of our total accounts receivable at September 30, 2017. At September 30, 2017, one
customer accounted for 80% of our total accounts receivable. Generally, our customers do not have an obligation to make purchases from us and may stop ordering our products
and services or may terminate existing orders or contracts at any time with little or no financial penalty. The loss of any of our significant customers, any substantial decline in
sales to these customers, or any significant change in the timing or volume of purchases by our customers could result in lower revenues and could harm our business, financial
condition or results of operations.

If our existing products and services are not accepted by potential customers or if we fail to introduce new products and services, our business, results of operations and
financial condition will be harmed.

There has been limited market acceptance of our DNA based technology, encapsulation, embedment and authentication products and services to date. Some of the factors that will
affect whether we achieve market acceptance of our solutions include:

● availability, quality and price relative to competitive solutions;

● customers’ opinions of the solutions’ utility;

● ease of use;

● consistency with prior practices;

● scientists’ opinions of the solutions’ usefulness; and

● general trends in anti-counterfeit and security solutions’ research.

Dependence on channel partners.

Our future growth will depend to a material extent on the successful advocacy of our technology by channel partners to their members and customers, and implementation of our
technology in solutions propagated by channel partners and provided by third parties. Our business has relied on the success of business partners. Our continuing success is
largely dependent on a new generation of business partners involved in our tagging technology.

If our channel partners are not successful in advocating and deploying our technology, we may not be able to achieve and sustain profitable operations. If other business partners
who include our technology in their products or otherwise license our intellectual property for use in their products cease to do so, or we fail to obtain other partners who will
incorporate, embed, integrate or bundle our technology, or these partners are unsuccessful in their efforts, expanding deployment of our technology and increasing revenues will
be adversely affected. Consequently, our ability to increase revenue could be adversely affected and we may suffer other adverse effects to our business. In addition, if our
technology does not perform according to market expectations, our future sales would suffer as customers seek and employ alternative technologies.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
27

 
 
Many of our business endeavors can be impeded or frustrated by larger, more influential companies or by standard-setting bodies or institutions downplaying, minimizing or
rejecting the value or use of our technology. A negative position by such companies, bodies or institutions, could result in obstacles for us that we would be incapable of
overcoming and may block or impede the adoption of our technology. In addition, potential customers may delay or reject initiatives that relate to deployment of our technology.
Such a development would make the achievement of our business objectives in this market difficult or impossible.

The expenses or losses associated with lack of widespread market acceptance of our solutions may harm our business, operating results and financial condition.

Rapid technological changes and frequent new product introductions are typical in the markets we serve. Our future success may depend in part on continuous, timely
development and introduction of new products that address evolving market requirements. We believe successful new product introductions may provide a significant competitive
advantage because customers invest their time in selecting and learning to use new products, and once invested in the new technology, are often reluctant to switch products. To
the extent we fail to introduce new and innovative products, we may lose any market share we then have to our competitors, which will be difficult or impossible to regain. Any
inability, for technological or other reasons, to successfully develop and introduce new products could reduce our growth rate or damage our business. We may experience delays
in the development and introduction of products. We may not keep pace with the rapid rate of change in anti-counterfeiting and security products’ research, and any new products
acquired or developed by us may not meet the requirements of the marketplace or achieve market acceptance.

We need to expand our sales, marketing and support organizations and our distribution arrangements to increase market acceptance of our products and services.

We currently have a limited number of sales, marketing, customer service and support personnel and may need to increase our staff to generate a greater volume of sales and to
support any new customers or the expanding needs of existing customers. The employment market for sales, marketing, customer service and support personnel in our industry is
very competitive, and we may not be able to hire the kind and number of sales, marketing, customer service and support personnel we are targeting. Our inability to hire qualified
sales, marketing, customer service and support personnel may harm our business, operating results and financial condition. While we have entered into a limited number of
agreements with distributors, we may not be able to sufficiently build out a distribution network or enter into arrangements with qualified distributors on acceptable terms or at all.
If we are not able to develop greater distribution capacity, we may not be able to generate sufficient revenue to support our operations.

We may have conflicts of interest with our affiliates and related parties, and in the past we have engaged in transactions and entered into agreements with affiliates that were
not negotiated at arms’ length.

We have engaged, and may in the future engage, in transactions with affiliates and other related parties. These transactions may not have been, and may not be, on terms as
favorable to us as they could have been if obtained from non-affiliated persons. While an effort has been made and will continue to be made to enter into transactions with
affiliated persons and other related parties at rates and on terms as favorable as would be charged by others, there will always be an inherent conflict of interest between our
interests and those of our affiliates and related parties. In August and November 2018, we issued an aggregate of $2.2 million in principal amount of secured convertible notes, a
majority of which are owned by our chairman, president and chief executive officer. These convertible notes may be converted into common stock, which, if converted by Dr.
Hayward, would increase the amount of control he has over the Company. The Company may be adversely impacted if any related party agreement or transaction is made on
unfavorable terms.

If we are unable to continue to retain the services of Dr. Hayward, we may not be able to continue our operations.

Our success depends to a significant extent upon the continued service of Dr. James A. Hayward, our Chairman, Chief Executive Officer and President. On July 28, 2016, we entered
into an employment agreement with Dr. Hayward. The initial term was from July 1, 2016 through June 30, 2017, with automatic one-year renewal periods. As of June 30, 2018, the
employment contract renewed for an additional year. Loss of the services of Dr. Hayward could significantly harm our business, results of operations and financial condition. We
do not maintain key-person insurance on the life of Dr. Hayward.

We may have conflicts of interest with our affiliates and related parties, and in the past we have engaged in transactions and entered into agreements with affiliates that were
not negotiated at arms’ length.

We have engaged, and may in the future engage, in transactions with affiliates and other related parties. These transactions may not have been, and may not be, on terms as
favorable to us as they could have been if obtained from non-affiliated persons. While an effort has been made, and will continue to be made, to enter into transactions with
affiliated persons and other related parties at rates and on terms as favorable as would be charged by others, there will always be an inherent conflict of interest between our
interests and those of our affiliates and related parties. In August 2018 and November 2018, we issued an aggregate of $2.2 million in principal amount of secured convertible notes,
a majority of which are owned by our chairman, president and chief executive officer. These convertible notes may be converted into common stock, which, if converted by Dr.
Hayward, would increase the amount of control he has over the Company. The Company may be adversely impacted if any related party agreement or transaction is made on
unfavorable terms.

The markets for our supply chain security and product authentication solutions are very competitive, and we may be unable to continue to compete effectively in these
industries in the future.

The principal markets for our offerings are intensely competitive. We compete with many existing suppliers and new competitors continue to enter the market. Many of our
competitors, both in the United States and elsewhere, are major pharmaceutical, chemical and biotechnology companies, or have strategic alliances with such companies, and many
of them have substantially greater capital resources, marketing experience, research and development staff, and facilities than we do. Any of these companies could succeed in
developing products that are more effective than the products that we have or may develop and may be more successful than us in producing and marketing their existing
products. Some of our competitors that operate in the anti-counterfeiting and fraud prevention markets include: 3DTL Inc., Alp Vision Sa, Authentix Inc., Brandwatch
Technologies, Chromologic LLC, Collectors Universe Inc., Collotype Labels International, Data Dot Technology, De La Rue Plc., Digimarc Corp., DNA Technologies, Inc., DuPont
Authentication Systems, FractureCode Corporation, Haelixa, ICA Bremen GmbH, ID Global Solutions Corporation, IEHCorporationInformium AG, Eastman Kodak Company, L-1
Identity Solutions Inc., opSec Security Group plc., MicroTagTemed Ltd., Nanotech Security Corp., Nokomis, Inc., Oritain Global Limited, ProoftagSAS, SafeTraces Inc., Selectamark
Security Systems plc, Spectra Systems Corp., SmartWater Technology, Inc., Sun Chemical Corp, TraceTag International, TruTag Technologies Inc., YottaMark Inc., Safe Traces,
Inc.

We expect this competition to continue and intensify in the future. Competition in our markets is primarily driven by:

● product performance, features and liability;

● price;

● timing of product introductions;

● ability to develop, maintain and protect proprietary products and technologies;

28

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
● sales and distribution capabilities;

● technical support and service;

● brand loyalty;

● applications support; and

● breadth of product line.

If a competitor develops superior technology or cost-effective alternatives to our products, our business, financial condition and results of operations could be significantly
harmed.

Revenues from our customer contracts with respect to cotton will be seasonal and may also be subject to weather conditions and other factors beyond our control, which may
cause our operating results to fluctuate significantly quarterly and annually.

A significant proportion of our revenues is expected to derive from customer contracts for tagging, authentications and other services related to cotton. The cotton ginning season
in the United States takes place between September and March each year. Therefore, revenues from our customer contracts relating to cotton will be seasonal, which may cause
our operating results to fluctuate significantly quarterly and annually. Additionally, weather and climatic conditions, natural disasters and other factors beyond our control also
affect the production and sale of cotton and other agricultural commodities to which our customer contracts may relate, as well as our customers’ or prospective customers’
decisions regarding purchases of our products and services, and may cause our operating results to fluctuate significantly quarterly and annually. The seasonal fluctuations in
operating results described above may cause a decline in the price of our common stock.

Fluctuations in quarterly results.

Our revenues and profitability are difficult to predict due to the nature of the markets in which we compete, fluctuating user demand, the uncertainty of current and future global
economic conditions, and for many other reasons, including that our operating results are highly dependent on the volume and timing of orders received during a quarter, which
are difficult to forecast. Customers generally order on an as-needed basis and we typically do not obtain firm, long-term purchase commitments from our customers.

Shifting enforcement priorities of U.S. federal laws relating to cannabis.

The Company is currently developing supply chain solutions for the cannabis industry. These solutions are intended to verify the authenticity, origin and provenance of cannabis.
Cannabis is a Schedule I substance as defined under U.S. federal law, and its possession and use is generally not permitted under U.S. federal law, although a number of individual
states have enacted state laws to authorize possession, sale and use of cannabis for medical purposes, and in some states for recreational purposes. Our solutions will be utilized
in those U.S. states where cannabis possession, sale and/or use is legal under state law. While our cannabis supply chain solutions are distinct from cannabis itself, our cannabis
supply chain business and related revenue may nevertheless be adversely impacted by such laws at the federal and/or state level in the United States, or potentially in foreign
jurisdictions. It is possible that such laws may result in our cannabis supply chain business having no revenues or may subject the Company to increased risk of litigation.

Pharmaceutical and biologic-related revenue is generally dependent on regulatory approval, oversight and compliance.

All of our pharmaceutical and biologic product candidates will require significant preclinical and clinical development before we can seek regulatory approval for them and launch a
product commercially. The sale and use of our products and services in the pharmaceutical and biologic markets will generally be subject to regulatory approval and oversight,
potentially including approval and/or oversight in various foreign jurisdictions. In addition, our pharmaceutical and biologic products and services may be incorporated into
products that cannot be marketed in the United States or in many other jurisdictions without approval by the FDA or comparable agencies of other countries or regions. Obtaining
such regulatory approvals is costly, time-consuming, uncertain, and subject to unanticipated delays. When, if ever, such approvals will be obtained is unknown. Our revenue in
the pharmaceutical and biologic markets, including revenue from our agreements with Colorcon is highly dependent upon obtaining such approval.

Federal agencies, including the FDA and Federal Trade Commission (“FTC”), as well as state, local, and foreign authorities, also exercise ongoing review and control of the
manufacturing, packaging, labeling, advertising, sale, distribution, and monitoring of pharmaceutical and biologic products. If our pharmaceutical or biologic product candidates or
pharmaceutical or biologic products incorporating our products are ever approved, failure to comply with any of these regulations or other requirements could also have an
adverse effect on our revenue in the pharmaceutical and biologic markets.

29

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Pharmaceutical and biologic-related revenue will be highly dependent on our collaborators’ and customers’ success in obtaining regulatory approval and commercializing
their products.

Some of our products in the pharmaceutical and biologic market will be incorporated into products that are subject to comprehensive regulation by the FDA and other regulatory
agencies in the United States and by comparable authorities in other countries. In the United States, to obtain approval from the FDA to market any future pharmaceutical or
biologic product that incorporates our technology, our collaborators or customers will be required to submit a New Drug Application (“NDA”) or Biologics Licensing Application
(“BLA”), ordinarily, the FDA requires a company to support an NDA or BLA, with substantial evidence of the product candidate's safety and efficacy in treating the targeted
indication based on data derived from adequate and well-controlled clinical trials, including Phase III safety and efficacy trials conducted in patients with the disease or condition
being targeted. The process of obtaining such regulatory approvals is expensive, often takes many years if approval is obtained at all, and can vary substantially based upon the
type, complexity and novelty of the product candidate involved. Changes in the regulatory approval process during the development period, changes in or the enactment of
additional statutes or regulations, or changes in the regulatory review process may cause delays in the approval or rejection of an application. There is no guarantee that our
collaborators and customers will ever be successful in obtaining regulatory approval for any product that incorporates our products or technology. Even if regulatory approval is
received, the manufacturing processes, post approval clinical data, labeling, advertising and promotional activities for any such product will be subject to continual requirements of
and review by the FDA and other regulatory bodies. Our business may be materially harmed by our collaborators’ and customers’ inability to obtain or maintain regulatory
approvals for their products.

In addition, we will be dependent on, and have no control over, consumer demand for the products into which our products are incorporated. Consumer demand for our
collaborators’ and customers’ products could be adversely affected by, among other things, delays in health regulatory approval, the loss of patent and other intellectual property
rights protection, the emergence of competing products, including generic drugs or biosimilars, the degree to which private and government drug plans subsidize payment for a
particular product and changes in the marketing strategies for such products. The healthcare industry has changed significantly over time, and we expect the industry to continue
to evolve. Some of these changes may have a material adverse effect on our collaborators and customers and thus may have a material adverse effect on our business. If the
products into which our products are incorporated do not gain market acceptance, our revenues and profitability may be adversely affected.

Pharmaceutical and biologic products are highly complex, and if we or our collaborators and customers are unable to provide quality and timely offerings to our respective
customers, our business could suffer.

The process of manufacturing pharmaceutical and biologics and their components is complex, highly-regulated and subject to multiple risks.

Manufacturing biologics is highly susceptible to product loss due to contamination, equipment failure, improper installation or operation of equipment, vendor or operator error,
inconsistency in yields, variability in product characteristics and difficulties in scaling the production process. Even minor deviations from normal manufacturing processes could
result in reduced production yields, product defects and other supply disruptions.

Our ability to generate revenue in the pharmaceutical and biologic market depends on our ability to manufacture products that meet exacting quality and safety standards. If we are
unable to manufacture these products to the required levels, it could have an adverse effect on our business, financial condition, and results of operations and may subject us to
regulatory actions, including product recalls, product seizures, injunctions to halt manufacture or distribution, restrictions on our operations, or civil sanctions, including monetary
sanctions and criminal actions. In addition, we could be subject to costly litigation, including claims from our collaborators and customers for reimbursement for the cost of our
products or other related losses, the cost of which could be significant.

Our business also depends on the ability of our collaborators and customers to manufacture the pharmaceutical or biologic products that incorporate our products. If the FDA
determines that our collaborators and customers are not in compliance with FDA laws and regulations, including those governing Current Good Manufacturing Practice
regulations (“cGMPs”), the FDA may deny NDA or BLA approval until the deficiencies are corrected. Even if our collaborators or customers obtain regulatory approval for any of
their product candidates, there is no assurance that they will be able to manufacture the approved product to specifications acceptable to the FDA or other regulatory authorities,
to produce it in sufficient quantities to meet the requirements for the potential launch of the product or to meet potential future demand. If our collaborators or customers are
unable to produce sufficient quantities for clinical trials or for commercialization, commercialization efforts would be impaired, which would have an adverse effect on our business,
financial condition, results of operations and growth prospects.

Pharmaceutical and biologic-related revenue will be dependent on our collaborators’ and customers’ demand for our manufacturing services.

The amount of customer spending on biologic development and manufacturing will have an impact on our sales and profitability in the pharmaceutical and biologic market. Our
collaborators and customers determine the amounts that they will spend based upon, among other things, available resources, access to capital, and their need to develop new
products, which, in turn, are dependent upon a number of factors, including their competitors’ research, development and product initiatives and the anticipated market uptake, and
clinical and reimbursement scenarios for specific products and therapeutic areas. Consolidation in the pharmaceutical and biologic industry may impact such spending as
customers integrate acquired operations, including R&D departments and manufacturing operations. Any reduction in spending on pharmaceutical and biotechnology
development and related services as a result of these and other factors could have a material adverse effect on our business, results of operations and financial condition.

30

 
 
 
 
 
 
 
 
 
 
 
 
 
 
The markets for our drug and biologic candidates and linear DNA are very competitive, and we may be unable to continue to compete effectively in these industries in the
future.

The principal markets for our drug and biologic candidates and linear DNA are intensely competitive. We compete with many existing suppliers and new competitors continue to
enter the market. Many of our competitors, both in the United States and elsewhere, are major pharmaceutical, chemical and biotechnology companies, or have strategic alliances
with such companies, and many of them have substantially greater capital resources, marketing experience, research and development staff, and facilities than we do. Any of these
companies could succeed in developing products that are more effective than the product candidates that we have or may develop and may be more successful than us in
producing and marketing their existing products. Some of our competitors that operate in the drugs, biologics and DNA manufacturing markets include: Intrexon Corp,. Aldervron,
LLC, Cobra Biologics, Limited, Integrated DNA Technologies, Inc., Ziopharm Oncology, Inc., MaxCyte Inc., Touchlight Genetics Ltd. Novartis AG, Kite Pharma, Inc. and Juno
Therapeutics, Inc.

We expect this competition to continue and intensify in the future. Our competitors also compete with us in recruiting and retaining qualified scientific and management personnel,
as well as in acquiring technologies complementary to, or necessary for, our programs. Our commercial opportunities could be reduced or eliminated if our competitors develop and
commercialize drug and biologic candidates or linear DNA that are safer, more effective, have fewer or less severe side effects, are more convenient, or are less expensive than any
drug and biologic candidates and linear DNA that we may develop. Our competitors also may obtain FDA or other regulatory approval for their products more rapidly than we may
obtain approval for ours, which could result in our competitors establishing a strong market position before we are able to enter the market. Additionally, drug and biologic
candidates and linear DNA developed by our competitors may render our potential drug and biologic candidates and linear DNA uneconomical or obsolete, and we may not be
successful in marketing any drug and biologic candidates and linear DNA we may develop against competitors.

If any of these risks occur, our business, financial condition and results of operations could be significantly harmed.

Our research and development efforts for new products may be unsuccessful.

We incur research and development expenses to develop new products and technologies in an effort to maintain our competitive position in a market characterized by rapid rates
of technological advancement. Our research and development efforts are subject to unanticipated delays, expenses and technical problems. There can be no assurance that any of
these products or technologies will be successfully developed or that, if developed, will be commercially successful. In the event that we are unable to develop commercialized
products from our research and development efforts or we are unable or unwilling to allocate amounts beyond our currently anticipated research and development investment, we
could lose our entire investment in these new products and technologies. Any failure to translate research and development expenditures into successful new product introduction
could have an adverse effect on our business.

In addition, research, development, and commercialization of pharmaceutical and biologic products is inherently risky. We cannot give any assurance that any of our
pharmaceutical and biologic product candidates will receive regulatory approval, which is necessary before they can be commercialized.

Other risks include:

• Our preclinical programs may experience delays or may never advance to clinical trials, which would adversely affect our ability to obtain regulatory approvals or commercialize
these programs on a timely basis or at all, which would have an adverse effect on our business.

• We have no history of commercializing pharmaceutical products, which may make it difficult to evaluate the prospects for our future viability.

• If the FDA rejects an IND submitted by us or places us on clinical hold, we will not be able to commence a Phase 1 clinical trial in the U.S., which would likely have a material
adverse effect on us.

• We have never dosed any of our product candidates in humans. Our clinical trials may reveal significant adverse events, toxicities or other side effects not seen in our preclinical
studies and may result in a safety profile that could inhibit regulatory approval or market acceptance of any of our product candidates.

• Positive results from early preclinical studies of our product candidates are not necessarily predictive of the results of later preclinical studies and any future clinical trials of our
product candidates. If we cannot show positive results or replicate any positive results from our earlier preclinical studies of our product candidates in our later preclinical studies
and future clinical trials, we may be unable to successfully develop, obtain regulatory approval for and commercialize our product candidates.

• We may not be successful in our efforts to create a pipeline of product candidates or to develop commercially successful products. If we fail to successfully identify and develop
additional product candidates, our commercial opportunity may be limited.

• If we receive authorization to conduct our clinical trials, we may encounter substantial delays in our clinical trials, or may not be able to conduct or complete our clinical trials on
the timelines we expect, if at all.

• We may encounter difficulties enrolling patients in our clinical trials, and our clinical development activities could thereby be delayed or otherwise adversely affected.

• Our clinical trials may fail to demonstrate substantial evidence of the safety and efficacy of our product candidates, which would prevent, delay or limit the scope of regulatory
approval and commercialization.

• Clinical development is a lengthy and expensive process with an uncertain outcome, and failure can occur at any stage of clinical development. If we are unable to design,
conduct and complete our clinical trials successfully, our product candidates will not be able to receive regulatory approval.

• We face significant competition in an environment of rapid technological and scientific change, and there is a possibility that our competitors may achieve regulatory approval
before us or develop therapies that are safer, more advanced or more effective than ours, which may negatively impact our ability to successfully market or commercialize any
product candidates we may develop and ultimately harm our financial condition.

• The manufacture of our product candidates is complex and difficulties may be encountered in production. If such difficulties are encountered or failure to meet regulatory
standards occurs, our ability to provide supply of our product candidates for clinical trials or our products for patients, if approved, could be delayed or stopped, or we may be
unable to maintain a commercially viable cost structure.

• If, in the future, we are unable to establish sales and marketing capabilities or enter into agreements with third parties to sell and market any product candidates we may develop,
we may not be successful in commercializing those product candidates if and when they are approved.

• Even if any product candidates we develop receive marketing approval, they may fail to achieve the degree of market acceptance by physicians, patients, healthcare payors, and
others in the medical community necessary for commercial success.

• Even if we are able to commercialize any product candidates, such products may become subject to unfavorable pricing regulations, third party reimbursement practices, or
healthcare reform initiatives, which would harm our business.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
31

 
 
Failure to license new technologies could impair sales of our existing products or any new product development we undertake in the future.

To generate broad product lines, it is advantageous to sometimes license technologies from third parties rather than depend exclusively on the development efforts of our own
employees. As a result, we believe our ability to license new technologies from third parties may be important to our ability to offer new products. In addition, from time to time we
are notified of, or become aware of patents held by third parties that are related to technologies we are selling or may sell in the future. After a review of these patents, we may
decide to seek a license for these technologies from these third parties. There can be no assurance that we will be able to successfully identify new technologies developed by
others. Even if we are able to identify new technologies of interest, we may not be able to negotiate a license on favorable terms, or at all.

Our failure to manage our growth in operations and acquisitions of new product lines and new businesses could harm our business.

The recent growth in our operations could place a significant strain on our current management resources. To manage such growth, we may need to improve our:

● operations and financial systems;

● procedures and controls; and

● training and management of our employees.

Our future growth, if any, may be attributable to acquisitions of new product lines and new businesses. Future acquisitions, if successfully consummated, would likely create
increased working capital requirements, which would likely precede by several months any material contribution of an acquisition to our net income. Our failure to manage growth
or future acquisitions successfully could seriously harm our operating results. Also, acquisition costs could cause our operating results to vary significantly from quarter to
quarter. Furthermore, our stockholders would be diluted if we financed the acquisitions by incurring convertible debt or issuing securities.

A percentage of our sales occur outside of the U.S. As a result, we are subject to the economic, political, regulatory and other risks of international operations.

For fiscal 2018 and 2017, 45% and 27%, respectively, of our revenue was from customers located outside of the U.S. We believe that the revenue from the sale of our products and
services outside the U.S. will continue to grow in the near future. We intend to expand our international operations to the extent that suitable opportunities become available. Our
foreign operations and sales could be adversely affected as a result of:

● nationalization of private enterprises and assets;

● political or economic instability in certain countries and regions;

● differences in foreign laws, including increased difficulties in protecting intellectual property and uncertainty in enforcement of contract rights;

● the possibility that foreign governments may adopt regulations or take other actions that could directly or indirectly harm our business and growth strategy;

● credit risks;

● currency fluctuations;

● tariff and tax increases;

● export and import restrictions and restrictive regulations of foreign governments;

● shipping products during times of crisis or wars; and

● other risks inherent in foreign operations.

32

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
We are subject to numerous regulatory, legal, operational, and other risks as a result of our international operations which could adversely impact our businesses in many
ways.

As a U.S. company, we are required to comply with the economic sanctions and embargo programs administered by Office of Foreign Assets Control and similar multi-national
bodies and governmental agencies worldwide, and the Foreign Corrupt Practices Act (“FCPA”). A violation of a sanction or embargo program or of the FCPA or similar laws
prohibiting certain payments to governmental officials, such as the U.K. Bribery Act, could subject us, and individual employees, to a regulatory enforcement action as well as
significant civil and criminal penalties which could adversely impact our business and operations.

Failure to attract and retain qualified scientific, production and managerial personnel could harm our business.

Recruiting and retaining qualified scientific and production personnel to perform and manage prototype, sample, and product manufacturing and business development personnel
to conduct business development are critical to our success. In addition, our desired growth and expansion into areas and activities requiring additional expertise, such as clinical
testing, government approvals, production, sales and marketing will require the addition of new management personnel and the development of additional expertise by existing
management personnel. Because our industry is very competitive, we face significant challenges in attracting and retaining a qualified personnel base. Although we believe we
have been, and will continue to be, able to attract and retain these personnel, we cannot assure you that we will continue to be able to successfully attract qualified personnel in
the future. The failure to attract and retain these personnel or, alternatively, to develop this expertise internally would harm our business since our ability to conduct business
development and manufacturing would be reduced or eliminated, resulting in lower revenues. We generally do not enter into employment agreements requiring our employees to
continue in our employment for any period of time, with the exception of our Chief Executive Officer. See “—If we are unable to continue to retain the services of Dr. Hayward, we
may not be able to continue our operations” in this Item 1A.

33

 
 
 
 
 
 
 
 
Our intellectual property rights are valuable, and any inability to protect them could reduce the value of our products, services and brand.

Our patents, trademarks, trade secrets, copyrights and all of our other intellectual property rights are important assets for us. There are events that are outside of our control that
pose a threat to our intellectual property rights as well as to our products and services. For example, effective intellectual property protection may not be available in every country
in which our products and services are distributed. The efforts we have taken to protect our proprietary rights may not be sufficient or effective. Any significant impairment of our
intellectual property rights could harm our business or our ability to compete. Protecting our intellectual property rights is costly and time consuming. Any increase in the
unauthorized use of our intellectual property could make it more expensive to do business and harm our operating results. Although we seek to obtain patent protection for our
innovations, it is possible we may not be able to protect some of these innovations. Given the costs of obtaining patent protection, we may choose not to protect certain
innovations that later turn out to be important. There is always the possibility that the scope of the protection gained from one of our issued patents will be insufficient or deemed
invalid or unenforceable. We also seek to maintain certain intellectual property as trade secrets. The secrecy could be compromised by third parties, or intentionally or accidentally
by our employees, which would cause us to lose the competitive advantage resulting from these trade secrets.

Intellectual property litigation could harm our business, financial condition and results of operations.

Litigation regarding patents and other intellectual property rights is extensive in the drug and biotechnology industry. In the event of an intellectual property dispute, we may be
forced to litigate. This litigation could involve proceedings instituted by the U.S. Patent and Trademark Office or the International Trade Commission, as well as proceedings
brought directly by affected third parties. Intellectual property litigation can be extremely expensive, and these expenses, as well as the consequences should we not prevail, could
seriously harm our business.

If a third party claims an intellectual property right to technology we use, we might need to discontinue an important product or product line, alter our products and processes, pay
license fees or cease our affected business activities. Although we might under these circumstances attempt to obtain a license to this intellectual property, we may not be able to
do so on favorable terms, or at all. Furthermore, a third party may claim that we are using inventions covered by the third party’s patent rights and may go to court to stop us from
engaging in our normal operations and activities, including making or selling our products. These lawsuits are costly and could affect our results of operations and divert the
attention of managerial and technical personnel. A court may decide that we are infringing the third party’s patents and would order us to stop the activities covered by the
patents. In addition, a court may order us to pay the other party damages for having violated the other party’s patents. The drug and biotechnology industry has produced a
proliferation of patents, and it is not always clear to industry participants, including us, which patents cover various types of products or methods of use. The coverage of patents
is subject to interpretation by the courts, and the interpretation is not always uniform. If we are sued for patent infringement, we would need to demonstrate that our products or
methods of use either do not infringe the patent claims of the relevant patent and/or that the patent claims are invalid, and we may not be able to do this. Proving invalidity, in
particular, is difficult since it requires a showing of clear and convincing evidence to overcome the presumption of validity enjoyed by issued patents.

Because some patent applications in the United States may be maintained in secrecy until the patents are issued, because patent applications in the United States and many
foreign jurisdictions are typically not published until eighteen months after filing, and because publications in the scientific literature often lag behind actual discoveries, we
cannot be certain that others have not filed patent applications for technology covered by our or our licensor’s issued patents or pending applications or that we or our licensors
were the first to invent the technology. During the ordinary course of our business, we do not conduct “prior art” searches before filing a patent application. Our competitors may
have filed, and may in the future file, patent applications covering technology similar to ours. Any such patent application may have priority over our or our licensors’ patent
applications and could further require us to obtain rights to issued patents covering such technologies. If another party has filed a United States patent application on inventions
similar to ours, we may have to participate in an interference proceeding declared by the United States Patent and Trademark Office to determine priority of invention in the United
States. The costs of these proceedings could be substantial, and it is possible that such efforts would be unsuccessful, resulting in a loss of our United States patent position with
respect to such inventions.

Some of our competitors may be able to sustain the costs of complex patent litigation more effectively than we can because they have substantially greater resources. In addition,
any uncertainties resulting from the initiation and continuation of any litigation could have a material adverse effect on our ability to raise the funds necessary to continue our
operations.

Accidents related to hazardous materials could adversely affect our business.

Some of our operations require the controlled use of hazardous materials for chemical reactions and synthesis. These materials are common to molecular/biological/chemical
laboratories and require no special handling or regulation. Although we believe our safety procedures comply with the standards prescribed by federal, state, local and foreign
regulations, the risk of accidental contamination of property or injury to individuals from these materials cannot be completely eliminated. In the event of an accident, we could be
liable for any damages that result, which could seriously damage our business and results of operations.

34

 
 
 
 
 
 
 
 
 
 
 
 
 
Potential product liability claims could affect our earnings and financial condition.

We face a potential risk of liability claims based on our products and services. Though we have product liability insurance coverage which we believe is adequate, we may not be
able to maintain this insurance at reasonable cost and on reasonable terms. We also cannot assure that this insurance will be adequate to protect us against a product liability
claim, should one arise. In the event that a product liability claim is successfully brought against us, it could result in a significant decrease in our liquidity or assets, which could
result in the reduction or termination of our business.

A successful product liability claim or series of claims brought against us could cause our stock price to decline, and, if judgments exceed our insurance coverage, could adversely
affect our results of operations, prospects, and business. Product liability claims may result in impairment of our business reputation and other losses. 

Litigation generally could affect our financial condition and results of operations.

We generally may be subject to claims made by and required to respond to litigation brought by customers, former employees, former officers and directors, former distributors and
sales representatives, former consultants and vendors and service providers. We have faced such claims and litigation in the past and we cannot assure you that we will not be
subject to claims in the future. In the event that a claim is successfully brought against us, considering our lack of material revenue and the losses our business has incurred for the
period from our inception to September 30, 2018, this could result in a significant decrease in our liquidity or assets, which could result in the reduction or termination of our
business.

Business disruptions could seriously harm our future revenue and financial condition and increase our costs and expenses.

Our operations could be subject to earthquakes, power shortages, telecommunications failures, cyber-attacks or other vulnerabilities in our computer systems, terrorism, water
shortages, tsunamis, floods, hurricanes, typhoons, fires, extreme weather conditions, medical epidemics, political or economic instability, and other natural or manmade disasters or
business interruptions. The occurrence of any of these business disruptions could seriously harm our revenue and financial condition and increase our costs and expenses.

General economic conditions may adversely affect our business, operating results and financial condition.

A general weakening or decline in the global economy or a period of economic slowdown may have serious negative consequences for our business and operating results. Since
our customers incorporate our products into a variety of consumer goods, the demand for our products is subject to worldwide economic conditions and their impact on levels of
consumer spending. Some of the factors affecting consumer spending include general economic conditions, unemployment, consumer debt, reductions in net worth, residential real
estate and mortgage markets, taxation, energy prices, interest rates, consumer confidence and other macroeconomic factors. During periods of economic weakness or uncertainty,
demand for consumer goods incorporating our products may weaken, and current or potential customers may defer purchases of our products.

A cybersecurity incident and other technology disruptions could negatively affect our business and our relationships with customers.

We use technology in substantially all aspects of our business operations. The widespread use of technology, including mobile devices, cloud computing, and the internet, give
rise to cybersecurity risks, including security breach, espionage, system disruption, theft and inadvertent release of information. Our business involves the storage and
transmission of numerous classes of sensitive and/or confidential information and intellectual property, including information relating to customers and suppliers, private
information about employees, and financial and strategic information about us and our business partners. If we fail to effectively assess and identify cybersecurity risks associated
with the use of technology in our business operations, we may become increasingly vulnerable to such risks. Additionally, while we have implemented measures to prevent
security breaches and cyber incidents, our preventative measures and incident response efforts may not be entirely effective. The theft, destruction, loss, misappropriation, or
release of sensitive and/or confidential information or intellectual property, or interference with our information technology systems or the technology systems of third parties on
which we rely, could result in business disruption, negative publicity, brand damage, violation of privacy laws, loss of customers, potential liability and competitive disadvantage.

Risks Related to Regulatory Approval of Our Pharmaceutical and Biotherapeutic Product Candidates and Other Legal Compliance Matters

The regulatory approval processes of the FDA and comparable foreign regulatory authorities are lengthy, time consuming, and inherently unpredictable. If we are ultimately
unable to obtain regulatory approval for our product candidates, we will be unable to generate product revenue and our business will be substantially harmed.

The time required to obtain approval by the FDA and comparable foreign regulatory authorities is unpredictable, typically takes many years following the commencement of clinical
trials, and depends upon numerous factors, including the type, complexity and novelty of the product candidates involved. In addition, approval policies, regulations, or the type
and amount of clinical data necessary to gain approval may change during the course of a product candidate’s clinical development and may vary among jurisdictions, which may
cause delays in the approval or the decision not to approve an application. Regulatory authorities have substantial discretion in the approval process and may refuse to accept any
application or may decide that our data are insufficient for approval and require additional preclinical, clinical or other studies. We have not submitted for, or obtained regulatory
approval for any product candidate, and it is possible that none of our existing product candidates or any product candidates we may seek to develop in the future will ever obtain
regulatory approval. Applications for our product candidates could fail to receive regulatory approval for a variety of reasons. This lengthy approval process, as well as the
unpredictability of the results of clinical trials, may result in our failing to obtain regulatory approval to market any of our product candidates, which would significantly harm our
business, results of operations, and prospects.

35

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Our product candidates may cause undesirable side effects or have other properties that could halt their clinical development, prevent their regulatory approval, limit their
commercial potential, or result in significant negative consequences.

Adverse events or other undesirable side effects caused by our product candidates could cause us or regulatory authorities to interrupt, delay, or halt clinical trials and could
result in a more restrictive label or the delay or denial of regulatory approval by regulatory authorities. Side effects related to a drug or biologic could affect patient recruitment, the
ability of enrolled patients to complete the study, and/or result in potential product liability claims.

Additionally, if one or more of our product candidates receives marketing approval, and we or others later identify undesirable side effects or adverse events caused by such
products, a number of potentially significant negative consequences could result. Regulatory authorities may withdraw approvals of such product or impose restrictions on
distribution. They may require additional warnings or contraindications on the product label that could diminish the usage or otherwise limit the commercial success of the product.
We may be required to change the way the product is administered, conduct additional clinical trials or post-approval studies. We may be forced to suspend marketing of the
product; or required to create a REMS. In addition, our reputation may suffer. Any of these events could prevent us from achieving or maintaining market acceptance of the
particular product candidate, if approved, and could significantly harm our business, prospects, results of operations, and prospects.

Obtaining and maintaining regulatory approval of our product candidates in one jurisdiction does not mean that we will be successful in obtaining regulatory approval of
our product candidates in other jurisdictions.

Obtaining and maintaining regulatory approval of our product candidates in one jurisdiction does not guarantee that we will be able to obtain or maintain regulatory approval in
any other jurisdiction, but a failure or delay in obtaining regulatory approval in one jurisdiction may have a negative effect on the regulatory approval process in others. Approval
procedures vary among jurisdictions and can involve requirements and administrative review periods different from those in the United States, including additional preclinical
studies or clinical trials as clinical trials conducted in one jurisdiction may not be accepted by regulatory authorities in other jurisdictions. In many jurisdictions outside the United
States, a product candidate must be approved for reimbursement before it can be approved for sale in that jurisdiction. In some cases, the price that we intend to charge for our
products is also subject to approval. There could be significant delays, difficulties and costs for us and could delay or prevent the introduction of our products in certain
countries. Failure to comply with the regulatory requirements in international markets or failure to receive applicable marketing approvals could reduce our target market and harm
our ability to realize the full market potential of our product candidates.

Even if we obtain regulatory approval for a product candidate, our products will remain subject to extensive regulatory scrutiny.

If any of our product candidates are approved, they will be subject to ongoing regulatory requirements for manufacturing, labeling, packaging, storage, advertising, promotion,
sampling, record-keeping, conduct of post-marketing studies, and submission of safety, efficacy, and other post-market information, including both federal and state requirements
in the United States and requirements of comparable foreign regulatory authorities. Ongoing regulatory requirements include ensuring that quality control and manufacturing and
production procedures conform to cGMP regulations, and we will be subject to continual review and inspections to assess compliance with cGMP and adherence to commitments
made in any regulatory filings. Accordingly, we and others with whom we work must continue to expend time, money, and effort in all areas of regulatory compliance.

36

 
 
 
 
 
 
 
 
 
 
 
Any regulatory approvals that we receive for our product candidates will be subject to limitations on the approved indicated uses for which the product may be marketed and
promoted or to the conditions of approval (including the requirement to implement a REMS), or contain requirements for potentially costly post-marketing testing. We will be
required to report certain adverse reactions and production problems, if any, to the FDA and comparable foreign regulatory authorities. Any new legislation addressing drug or
biologic safety issues could result in delays in product development or commercialization, or increased costs to assure compliance. The FDA and other agencies, including the
Department of Justice, closely regulate and monitor the post-approval marketing and promotion of products to ensure that they are manufactured, marketed and distributed only
for the approved indications and in accordance with the provisions of the approved labeling. We will have to comply with requirements concerning advertising and promotion for
our products. Promotional communications with respect to prescription drugs and biologics are subject to a variety of legal and regulatory restrictions and must be consistent with
the information in the product’s approved label. As such, we may not promote our products for indications or uses for which they do not have approval. The holder of an
approved NDA must submit new or supplemental applications and obtain approval for certain changes to the approved product, product labeling, or manufacturing process. We
could also be asked to conduct post-marketing clinical trials to verify the safety and efficacy of our products in general or in specific patient subsets. If original marketing approval
was obtained via the accelerated approval pathway, we could be required to conduct a successful post-marketing clinical trial to confirm clinical benefit for our products. An
unsuccessful post-marketing study or failure to complete such a study could result in the withdrawal of marketing approval.

If a regulatory agency discovers previously unknown problems with a product, such as adverse events of unanticipated severity or frequency, or problems with the facility where
the product is manufactured, or disagrees with the promotion, marketing or labeling of a product, such regulatory agency may impose restrictions on that product or us, including,
but not limited to, requiring withdrawal or recall of the product from the market, imposing civil or criminal penalties, and imposing restrictions on our operations. Any government
investigation of alleged violations of law could require us to expend significant time and resources in response, and could generate negative publicity. Any failure to comply with
ongoing regulatory requirements may significantly and adversely affect our ability to commercialize and generate revenue from our products. If regulatory sanctions are applied or
if regulatory approval is withdrawn, the value of our company and our operating results will be adversely affected.

In addition, the FDA’s regulations, policies or guidance may change and new or additional statutes or government regulations in the United States and other jurisdictions may be
enacted that could further restrict or regulate post-approval activities. We cannot predict the likelihood, nature or extent of adverse government regulation that may arise from
pending or future legislation or administrative action. If we are not able to achieve and maintain regulatory compliance, we may not be permitted to market our products and/or
product candidates, which would adversely affect our ability to generate revenue and achieve or maintain profitability.

Healthcare legislative measures aimed at reducing healthcare costs may have a material adverse effect on our business and results of operations.

Third party payors are developing increasingly sophisticated methods of controlling healthcare costs. In both the United States and certain foreign jurisdictions, there have been a
number of legislative and regulatory changes to the health care system that could impact our ability to sell our products profitably. In particular, in the United States in 2010, the
ACA, was enacted. In addition, other legislative changes have been proposed and adopted in the United States since the ACA was enacted. The repeal of or changes in some or
all of the ACA and complying with any new legislation or reversing changes implemented under the ACA could be time-intensive and expensive, resulting in a material adverse
effect on our business. Until the ACA is fully implemented or there is more certainty concerning the future of the ACA, it will be difficult to predict its full impact and influence on
our business.

37

 
 
 
 
 
 
 
 
 
There have been, and likely will continue to be, legislative and regulatory proposals at the foreign, federal and state levels directed at containing or lowering the cost of healthcare.
We cannot predict the initiatives that may be adopted in the future. The continuing efforts of the government, insurance companies, managed care organizations and other payors
of healthcare services to contain or reduce costs of healthcare and/or impose price controls may adversely affect the demand for our product candidates, if we obtain regulatory
approval, including: our ability to receive or set a price that we believe is fair for our products; our ability to generate revenue and achieve or maintain profitability; the level of
taxes that we are required to pay; and the availability of capital. We expect that the ACA, as well as other healthcare reform measures that may be adopted in the future, may result
in additional reductions in Medicare and other healthcare funding, more rigorous coverage criteria, lower reimbursement, and new payment methodologies. This could lower the
price that we receive for any approved product. Any denial in coverage or reduction in reimbursement from Medicare or other government-funded programs may result in a similar
denial or reduction in payments from private payors, which may prevent us from being able to generate sufficient revenue, attain profitability or commercialize our product
candidates, if approved.

Our employees, independent contractors, consultants, commercial partners and vendors may engage in misconduct or other improper activities, including non-compliance
with regulatory standards and requirements.

We are exposed to the risk of fraud, misconduct or other illegal activity by our employees, independent contractors, consultants, commercial partners and vendors. Misconduct by
these parties could include intentional, reckless and negligent conduct that fails to: comply with the laws of the FDA and other comparable foreign regulatory authorities; provide
true, complete and accurate information to the FDA and other comparable foreign regulatory authorities; comply with manufacturing standards we have established; comply with
healthcare fraud and abuse laws in the United States and similar foreign fraudulent misconduct laws; or report financial information or data accurately or to disclose unauthorized
activities to us.

If we obtain FDA approval of any of our product candidates and begin commercializing those products in the United States, our potential exposure under such laws will increase
significantly, and our costs associated with compliance with such laws are also likely to increase. In particular, research, sales, marketing, education and other business
arrangements in the healthcare industry are subject to extensive laws designed to prevent fraud, kickbacks, self-dealing and other abusive practices. These laws and regulations
may restrict or prohibit a wide range of pricing, discounting, educating, marketing and promotion, sales and commission, certain customer incentive programs and other business
arrangements generally. Activities subject to these laws also involve the improper use of information obtained in the course of patient recruitment for clinical trials, which could
result in regulatory sanctions and cause serious harm to our reputation. We have adopted a code of business conduct and ethics, but it is not always possible to identify and deter
misconduct by employees and third parties, and the precautions we take to detect and prevent this activity may not be effective in controlling unknown or unmanaged risks or
losses or in protecting us from governmental investigations or other actions or lawsuits stemming from a failure to be in compliance with such laws. If any such actions are
instituted against us, and we are not successful in defending ourselves or asserting our rights, those actions could have a significant impact on our business, including the
imposition of significant fines or other sanctions.

If we fail to comply with healthcare laws, we could face substantial penalties and our business, operations and financial conditions could be adversely affected.

Healthcare providers, physicians and payors play a primary role in the recommendation and prescription of any product candidates for which we may obtain marketing approval.
Our future arrangements with payors and customers may expose us to broadly applicable fraud and abuse and other healthcare laws and regulations that may constrain the
business or financial arrangements and relationships through which we market, sell and distribute any product candidates for which we may obtain marketing approval. Even
though we do not and will not control referrals of healthcare services or bill directly to Medicare, Medicaid or other third party payors, federal and state healthcare laws and
regulations pertaining to fraud and abuse and patients’ rights are and will be applicable to our business. Restrictions under applicable federal, state and foreign healthcare laws and
regulations which may affect our ability to operate and expose us to areas of risk include: federal civil and criminal false claims laws and civil monetary penalty laws, including the
False Claims Act; HIPAA; HIPAA, as amended by HITECH; the federal Physician Payments Sunshine Act, created under the ACA, and its implementing regulations; federal
consumer protection and unfair competition laws, which broadly regulate marketplace activities and activities that potentially harm consumers; and analogous state and foreign
laws and regulations.

38

 
 
 
 
 
 
 
 
 
 
Because of the breadth of these laws and the narrowness of the statutory exceptions and safe harbors available, it is possible that some of our business activities could, despite
our efforts to comply, be subject to challenge under one or more of such laws. Efforts to ensure that our business arrangements will comply with applicable healthcare laws may
involve substantial costs. It is possible that governmental and enforcement authorities will conclude that our business practices may not comply with current or future statutes,
regulations or case law interpreting applicable fraud and abuse or other healthcare laws and regulations. If any such actions are instituted against us, and we are not successful in
defending ourselves or asserting our rights, those actions could have a significant impact on our business, including the imposition of civil, criminal and administrative penalties,
damages, disgorgement, monetary fines, possible exclusion from participation in Medicare, Medicaid and other federal healthcare programs, contractual damages, reputational
harm, diminished profits and future earnings, and curtailment of our operations, any of which could adversely affect our ability to operate our business and our results of
operations. In addition, the approval and commercialization of any of our product candidates outside the United States will also likely subject us to foreign equivalents of the
healthcare laws mentioned above, among other foreign laws.

If we or any suppliers we engage fail to comply with environmental, health, and safety laws and regulations, we could become subject to fines or penalties or incur costs that
could have a material adverse effect on the success of our business.

We and any suppliers we currently or may in the future engage are subject to numerous federal, state, and local environmental, health, and safety laws, regulations, and permitting
requirements, including those governing laboratory procedures; the generation, handling, use, storage, treatment, and disposal of hazardous and regulated materials and wastes;
the emission and discharge of hazardous materials into the ground, air, and water; and employee health and safety. Under certain environmental laws, we could be held responsible
for costs relating to any contamination at our current or past facilities and at third party facilities. We also could incur significant costs associated with civil or criminal fines and
penalties. Compliance with applicable environmental laws and regulations may be expensive, and current or future environmental laws and regulations may impair our research,
product development and manufacturing efforts. In addition, we cannot entirely eliminate the risk of accidental injury or contamination from these materials or wastes. Although we
maintain workers’ compensation insurance to cover us for costs and expenses we may incur due to injuries to our employees resulting from the use of hazardous materials, this
insurance may not provide adequate coverage against potential liabilities. We do not carry specific biological or hazardous waste insurance coverage, and our property, casualty,
and general liability insurance policies specifically exclude coverage for damages and fines arising from biological or hazardous waste exposure or contamination. Accordingly, in
the event of contamination or injury, we could be held liable for damages or be penalized with fines in an amount exceeding our resources, and our preclinical trials, future clinical
trials or regulatory approvals could be suspended, which could have a material adverse effect on our business, prospects, financial condition, results of operations, and prospects.

Risks Relating to Our Common Stock and Other Securities:

There are a large number of shares of common stock underlying our outstanding options and warrants and the sale of these shares may depress the market price of our
common stock and cause immediate and substantial dilution to our existing stockholders. The holders of our publicly traded warrants may require their repurchase in certain
circumstances.

As of December 14, 2018, we had 30,112,057 shares of common stock issued and outstanding, outstanding options to purchase 6,177,214 shares of common stock and outstanding
warrants to purchase 12,208,527 shares of common stock. The issuance of shares upon exercise of our outstanding options and warrants will cause immediate and substantial
dilution to our stockholders. Under our publicly traded warrants (including additional warrants sold privately that have registration rights), in the event of a “Fundamental
Transaction” (as defined in the related warrant agreement, which generally includes any merger with another entity, the sale, transfer or other disposition of all or substantially all
of our assets to another entity, or the acquisition by a person of more than 50% of our common stock), each warrant holder will have the right at any time prior to the
consummation of the Fundamental Transaction to require us to repurchase the warrant for a purchase price in cash equal to the Black Scholes value (as calculated under the
warrant agreement) of the then remaining unexercised portion of such warrant on the date of such Fundamental Transaction, which may materially adversely affect our financial
condition and/or results of operations and may prevent or deter a third party from acquiring us.

We may require additional financing which may in turn require the issuance of additional shares of common stock, preferred stock or other debt or equity securities
(including convertible securities) and which would dilute the ownership held by our stockholders.

We may need to raise funds through either debt or the sale of our shares of our common stock in order to achieve our business goals. Any additional shares issued would further
dilute the percentage ownership held by the stockholders. Furthermore, if we raise funds in equity transactions through the issuance of convertible securities which are convertible
at the time of conversion at a discount to the prevailing market price, substantial dilution is likely to occur resulting in a material decline in the price of your shares. Our public
offerings completed in November 2014 and April 2015, our registered direct public offering (the “Registered Direct Offering”) and concurrent private placement, during November
2015, our private placements completed in November 2016 and June 2017 our registered direct offering in December 2017, resulted in dilution to investors and future offerings of
securities could result in further dilution to investors. Our private placements of convertible notes in August 2018 and November 2018 could result in dilution to investors if the
holders convert their notes into shares of our common stock.

39

 
 
 
 
 
 
 
 
 
 
 
 
Conversion of our convertible notes into common stock will result in additional dilution to our stockholders.

Upon satisfaction of certain conversion conditions (including conditions outside of our control, such as market price or trading price) and proper conversion of the Notes by a
holder, we may be required to deliver shares of our common stock to a converting holder. If additional shares of our common stock are issued due to conversion of some or all of
the outstanding Notes, the ownership interests of existing stockholders will be diluted. Further, any sales in the public market of any shares of common stock issued upon
conversion or hedging or arbitrage trading activity that develops due to the potential conversion of the Notes could adversely affect prevailing market prices of our common stock.

Substantially all of our assets are encumbered. If we should fail to make timely payments on our secured convertible notes, holders of the notes may choose to enforce their
remedies and ultimately realize on the collateral securing the notes, which includes substantially all of our intellectual property.

On August 31, 2018 we entered into a securities purchase agreement pursuant to which we issued and sold an aggregate of $1.65 million in principal amount of secured convertible
notes and on November 29, 2018 we entered into a second securities purchase agreement pursuant to which we issued and sold an aggregate of $550 thousand in principal amount
of secured convertible notes (together, the “Notes”) which are due and payable in full on August 30, 2021 and November 28, 2021, respectively. A majority of the Notes are owned
by our chairman, president and chief executive officer. Until the principal and accrued but unpaid interest under the Notes is paid in full, or the Notes are converted into shares of
common stock, our obligations under the Notes are secured by a lien on substantially all of our assets (excluding certain cash accounts) and the assets of APDN (B.V.I.) Inc., our
wholly-owned subsidiary, in favor of CSC Corporation, as collateral agent for the purchasers of the Notes. The secured assets include substantially all of our intellectual property.
The existence of such lien may substantially limit our ability to obtain additional secured financing and force us to attempt to incur additional unsecured indebtedness, which may
be unavailable to us. If we should fail to make timely payments on the Notes, holders of the Notes may choose to enforce their remedies and ultimately realize on the collateral
securing the notes, which may have a material adverse effect on our business, including the inability for us to continue our operations.

We may require additional financing in the future, which may not be available or, if available, may be on terms that cause a decline in the value of the shares of our common
stock held by stockholders.

If we raise capital in the future by issuing additional securities, our stockholders may experience a decline in the value of the shares of our common stock they currently hold or
may acquire prior to any such financing. In addition, such securities may have rights senior to the rights of holders of our shares of common stock.

If we fail to comply with the continuing listing standards of The Nasdaq Capital Market, our securities could be delisted.

Our common stock and publicly traded warrants are listed on The Nasdaq Capital Market under the symbols “APDN” and “APDNW,” respectively. For our common stock and
publicly traded warrants to continue to be listed on The Nasdaq Capital Market, we must meet the current continued listing requirements, including the requirements that (1) our
stock must maintain a minimum closing bid price of $1.00 (the “Minimum Bid Price Requirement”); and (2) we must maintain net income from continuing operations (in the latest
fiscal year or two of the three last fiscal years) of at least $500,000, a market value of listed securities of at least $35 million or stockholders’ equity of at least $2.5 million (the
“Minimum Stockholders’ Equity Requirement”).

As of September 30, 2018, our stockholders’ equity was below the Minimum Stockholders’ Equity Requirement. We are currently evaluating potential solutions to regain
compliance with the Minimum Stockholders’ Equity Requirement. The Minimum Stockholders’ Equity Requirement is not subject to an automatic grace period. There can be no
assurance that we will meet the Minimum Stockholders’ Equity Requirement or the Minimum Bid Price Requirement during any compliance period or in the future, or otherwise meet
The Nasdaq Capital Market compliance standards, or that The Nasdaq Capital Market will grant the Company any relief from delisting as necessary, or that we will be able to
ultimately meet applicable The Nasdaq Capital Market requirements for any such relief.

If we were unable to meet The Nasdaq Capital Market’s listing requirements, our common stock and warrants could be delisted from The Nasdaq Capital
Market. If our securities were to be delisted from The Nasdaq Capital Market, our securities could begin to trade on the Over-The-Counter Bulletin Board or
on one of the markets operated by OTC Markets Group, including OTC Pink (formerly known as the “pink sheets”), as the case may be. In such event, our
securities could once again be subject to the “penny stock” rules which among other things require brokers or dealers to approve investors’ accounts, receive
written agreements and determine investor suitability for transactions and disclose risks relating to investing in the penny stock market. Any such delisting of our
securities could have an adverse effect on the market price of, and the efficiency of the trading market for our securities, not only in terms of the number of
shares that can be bought and sold at a given price, but also through delays in the timing of transactions and less coverage of us by securities analysts, if any.
Also, if in the future we were to determine that we need to seek additional equity capital, it could have an adverse effect on our ability to raise capital in the
public or private equity markets.

Any material weaknesses in our internal control over financing reporting in the future could adversely affect investor confidence, impair the value of our common stock and
increase our cost of raising capital.

Any failure to remedy deficiencies in our internal control over financial reporting that may be discovered or our failure to implement new or improved controls, or difficulties
encountered in the implementation of such controls, could harm our operating results, cause us to fail to meet our reporting obligations or result in material misstatements in our
financial statements. Any such failure could, in turn, affect the future ability of our management to certify that internal control over our financial reporting is effective. Inferior
internal control over financial reporting could also subject us to the scrutiny of the SEC and other regulatory bodies which could cause investors to lose confidence in our reported
financial information and could subject us to civil or criminal penalties or stockholder litigation, which could have an adverse effect on our results of operations and the market
price of our common stock.

In addition, if we or our independent registered public accounting firm identify deficiencies in our internal control over financial reporting, the disclosure of that fact, even if quickly
remedied, could reduce the market’s confidence in our financial statements and harm our share price. Furthermore, deficiencies could result in future non-compliance with Section
404 of the Sarbanes-Oxley Act of 2002. Such non-compliance could subject us to a variety of administrative sanctions, including review by the SEC or other regulatory authorities.

40

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Short sellers of our stock may be manipulative and may drive down the market price of our common stock.

Short selling is the practice of selling securities that the seller does not own but rather has borrowed or intends to borrow from a third party with the intention of buying identical
securities at a later date to return to the lender. A short seller hopes to profit from a decline in the value of the securities between the sale of the borrowed securities and the
purchase of the replacement shares, as the short seller expects to pay less in that purchase than it received in the sale. As it is therefore in the short seller’s interest for the price of
the stock to decline, some short sellers publish, or arrange for the publication of, opinions or characterizations regarding the relevant issuer, its business prospects and similar
matters calculated to or which may create negative market momentum, which may permit them to obtain profits for themselves as a result of selling the stock short. Issuers whose
securities have historically had limited trading volumes and/or have been susceptible to relatively high volatility levels can be particularly vulnerable to such short seller attacks.
The publication of any such commentary regarding us in the future may bring about a temporary, or possibly long term, decline in the market price of our common stock. In the
past, the publication of commentary regarding us by a disclosed short seller has been associated with the selling of shares of our common stock in the market on a large scale,
resulting in a precipitous decline in the market price per share of our common stock. No assurances can be made that similar declines in the market price of our common stock will
not occur in the future, in connection with such commentary by short sellers or otherwise.

The price of our common stock may be volatile or may decline, and the trading volume of our common stock may fluctuate, which may make it more difficult to realize a
profit on your investment in our shares of common stock.

Our common stock is listed on The Nasdaq Capital Market. The trading price of our common stock has been and may continue to be volatile. In addition, the trading volume of our
common stock may fluctuate and cause significant price variations to occur. Volatility in the market price of our common stock may prevent you from being able to sell your shares
of common stock at or above the price you paid for your shares of common stock, which may make it more difficult to realize a profit on your investment. A number of factors may
affect the market price of our common stock, including, but not limited to, the following:

·

·

·

·

·

·

·

·

·

·

·

·

·

·

·

·

·

·

·

our operating and financial performance and prospects;

our quarterly or annual earnings or those of other companies in our industry or that investors deem comparable to us;

conditions that impact demand for our products and services;

public reactions to our press releases, other public announcements and filings with the SEC;

market and industry perception of our success, or lack thereof, in pursuing our growth strategy;

strategic actions by us or our competitors, such as acquisitions or restructurings;

changes in accounting standards, policies, guidance, interpretations or principles;

arrival and departure of key personnel, including management personnel;

changes in our capital structure;

changes in the price of our warrants or other securities we may issue from time to time;

sales of common stock by us, our directors, officers or large stockholders;

the expiration of any applicable contractual lock-up agreements;

changes in general market, economic and political conditions in the United States and global economies or financial markets, including those resulting from
natural disasters, terrorist attacks, acts of war and responses to such events;

announcements of new products or innovations by us or our competitors and announcements concerning our competitors or our industry in general;

difficulties in commercialization and distribution of our products or lower than expected sales volume or revenues;

changes in our relationships with manufacturers, suppliers or collaborators, or our inability to supply enough product to meet demand;

our ability to obtain additional funding;

changes or developments in applicable laws or regulations;

any intellectual property infringement actions or other litigation or legal proceeding in which we may become involved;

41

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
·

·

·

changes in financial estimates or recommendations by securities analysts, or their ceasing to publish research or reports about our business;

the trading volume of our common stock; and

the appeal and current level of investor interest in the biotechnology/biopharmaceutical capital market sector and in companies in general with business, research
strategies and product development pipelines which are similar to us.

In addition, The Nasdaq Capital Market and other securities markets have, from time to time, experienced extreme price and trading volume fluctuations. The market prices of
securities of biotechnology and other life sciences companies in a comparable stage to ours historically have been particularly volatile, and trading volume in such securities and
our common stock has often been relatively low. Moreover, the securities and financial markets in general have experienced substantial volatility that has often been unrelated or
disproportionate to the operating results of any individual company. During certain periods, specific industry sectors, such as the biotechnology segment, may experience greater
volatility than other sectors or the securities markets as a whole. These broad market fluctuations, during which our industry and companies at our stage may experience a stronger
degree of market sensitivity, will adversely affect the market price of our common stock.

In the past, following periods of volatility in the market price of a company’s securities, stockholders have often instituted class action securities litigation against those
companies. Such litigation, if instituted, could result in substantial costs and diversion of management attention and resources, which could significantly harm our reputation and
materially adversely affect our business, financial condition and results of operations.

ITEM 1B.

UNRESOLVED STAFF COMMENTS.

None.

ITEM 2.

PROPERTIES.

Our corporate headquarters is located at the Long Island High Technology Incubator (“LIHTI”), which is located on the campus of Stony Brook University at 50 Health Sciences
Drive, Stony Brook, NY 11790. The lease is for a 30,000 square foot building. The term of the lease commenced on June 15, 2013 and expired on May 31, 2016, with the option to
extend the lease for two additional three-year periods. We have exercised our option to extend the lease for one additional three-year period, ending May 31, 2019. The base rent
during the additional three-year period is $458,098 per annum. In addition to the office space, we also have 1,500 square feet of laboratory space. The term of the lease commenced
on November 1, 2015, expired on October 31, 2016 and was renewed through October 31, 2017. Effective November 20, 2017, we have renewed this lease for one additional year
ending October 31, 2018, with a month to month agreement thereafter. We set up a satellite testing facility in Ahmedabad, India during fiscal 2018. On November 17, 2017, we leased
1,108 square feet for a three-year term beginning November 1, 2017. The base rent is approximately $6,500 per annum.

ITEM 3.

LEGAL PROCEEDINGS.

From time to time, we may become involved in various lawsuits and legal proceedings which arise in the ordinary course of business. However, litigation is subject to inherent
uncertainties, and an adverse result in these or other matters may arise from time to time that may harm our business. We are currently not aware of any such legal proceedings that
we believe will have, individually or in the aggregate, a material adverse effect on our business, financial condition or operating results.

ITEM 4.

MINE SAFETY DISCLOSURES.

Not applicable.

42

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
PART II

ITEM 5.

MARKET FOR COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND ISSUER PURCHASES OF EQUITY SECURITIES.

Market Information

Our common stock is listed on The NASDAQ Capital Market under the symbol “APDN”. Our warrants are listed on The NASDAQ Capital Market under the symbol “APDNW”.
There is no certainty that the common stock and warrants will continue to be listed or that any liquidity exists for our stockholders, or warrant holders.

The following table sets forth the quarterly quotes of high and low prices for our common stock and warrants on The NASDAQ Capital Market, during the fiscal years ended
September 30, 2018 and 2017:

Common Stock:
First Quarter
Second Quarter
Third Quarter
Fourth Quarter

Warrants:
First Quarter
Second Quarter
Third Quarter
Fourth Quarter

Holders

Fiscal 2018

Fiscal 2017

High

Low

High

Low

3.45    $
1.75    $
1.59    $
1.84    $

1.52    $
1.36    $
1.21    $
1.10    $

3.15    $
2.05    $
1.94    $
2.88    $

Fiscal 2018

Fiscal 2017

High

Low

High

Low

0.85    $
0.44    $
0.36    $
0.30    $

0.21    $
0.25    $
0.12    $
0.13    $

1.16    $
0.55    $
0.50    $
1.04    $

1.73 
1.40 
1.94 
1.55 

0.35 
0.35 
0.22 
0.30 

  $
  $
  $
  $

  $
  $
  $
  $

As of December 10, 2018, we had approximately 576 holders of record of our common stock and 3 holders of record of our publicly traded warrants. The number of record holders
was determined from the records of our transfer agent and does not include beneficial owners of common stock whose shares are held in the names of various security brokers,
dealers, and registered clearing agencies. The transfer agent of our common stock and warrants is American Stock Transfer & Trust Company, 6201 15th Avenue, Brooklyn, New
York 11219.

Dividends

We have never declared or paid any cash dividends on our common stock. We do not anticipate paying any cash dividends to stockholders in the foreseeable future. In addition,
any future determination to pay cash dividends will be at the discretion of the Board of Directors and will be dependent upon our financial condition, results of operations, capital
requirements, and such other factors as the Board of Directors deem relevant.

ITEM 6.

SELECTED FINANCIAL DATA.

Information requested by this Item is not applicable as we are electing scaled disclosure requirements available to Smaller Reporting Companies with respect to this Item.

ITEM 7.

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS.

The following Management’s Discussion and Analysis of Financial Condition and Results of Operations should be read in conjunction with our consolidated financial statements
and the related notes appearing elsewhere in this Annual Report on Form 10-K. This discussion and analysis includes certain forward-looking statements that involve risks,
uncertainties and assumptions. You should review the Risk Factors section of this Form 10-K for a discussion of important factors that could cause actual results to differ
materially from the results described in or implied by such forward-looking statements. See “Forward-Looking Information” at the beginning of this Form 10-K.

43

 
 
 
 
 
 
 
 
 
   
 
 
 
 
   
 
   
 
   
 
 
 
   
   
   
 
 
 
 
   
 
 
 
 
   
 
   
 
   
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
Introduction

Using our large scale polymerase chain reaction (PCR) based manufacturing platform we manufacture large quantities of linear DNA for various markets. Whether for supply chain
security, brand protection, law enforcement or drug and biologic applications, it is our goal to help establish secure flourishing environments that foster quality, integrity and
success. With secure taggants, high-resolution DNA authentication, and comprehensive reporting, our SigNature molecular tag technologies are designed to deliver what we
believe to be the greatest levels of security, deterrence and legal recourse strength. Under our wholly owned subsidiary, LRx, we supply DNA for the use in in vitro medical
diagnostics, preclinical biotechnology and drug and biologic manufacturing markets, and are also engaged in preclinical and animal drug candidate development and
commercialization activities focusing on therapeutically relevant DNA drug constructs manufacturers via through our PCR-based DNA production platform Triathlon™ PCR
systems.

General

To date, the substantial portion of our revenues have been generated from sales of our SigNature molecular tags and SigNature T molecular tags, our principal supply chain
security and product authentication solutions. We expect to grow revenues from sales of our SigNature molecular tags, SigNature T molecular tags, SigNify, and CertainT offerings
as we work with companies and government to secure supply chains for various types of products and product labeling throughout the world. In addition, we expect to continue
to grow revenues from our PCR-produced linear DNA products and services for in vitro medical diagnostics, biotechnology research and drug and biologic manufacturing. We
have continued to incur expenses in expanding our business and increasing our personnel to meet current and anticipated future demand. We have limited sources of liquidity. Our
products and services are offered in the United States, Europe and Asia. At the present time, we are focusing our efforts on textile and apparel, pharmaceuticals and nutraceuticals,
microcircuits and other electronics, cannabis and PCR-produced linear DNA products and services (for therapeutics, diagnostics and vaccines). Currently approximately twenty
percent of our annual revenue comes from the textile market. The cotton ginning season in the United States takes place between September and March each year; therefore,
revenues from our cotton customer contracts may be seasonal and recognized primarily during our first and fourth fiscal quarters, which may cause operating results to fluctuate
significantly quarterly and annually. The basic technology we use in various markets is very similar, and we believe our solutions are adaptable for many types of products and
markets.

We have continued to incur expenses in expanding our business to meet current and anticipated future demand. We have limited sources of liquidity. Our independent registered
public accounting firm has included an explanatory paragraph relating to our ability to continue as a going concern in its report on our audited financial statements for the year
ended September 30, 2018 included in this Annual Report on Form 10-K. Our products and services are offered in the United States, Europe and Asia. At the present time, we are
focusing our efforts on textile and apparel, pharmaceuticals and nutraceuticals, microcircuits and other electronics, bulk DNA production (for therapeutics, diagnostics and
vaccines), cash-in-transit, consumer asset marking, printing and packaging businesses, and agrochemicals. The basic technology we use in various markets is very similar, and we
believe our solutions are adaptable for many types of products and markets.

In addition, we seek to develop, acquire and commercialize, along with partners, a diverse portfolio of nucleic acid based therapeutics based on PCR-produced linear DNA to
improve existing nucleic acid-based therapeutics or create new nucleic acid-based therapeutics that address unmet medical needs. We are also engaged in preclinical and animal
drug candidate development activities focusing on therapeutically relevant drug construct manufacturers through our Triathlon™ PCR systems. LRx uses the Triathlon™ PCR
system to rapidly produce customized DNA for use by our CRO/CMO clients, our drug and biologic partners, and for our proprietary pre-clinical gene therapies. LRx’s proprietary
process enables large, gram-scale production of DNA through PCR for bio-based therapeutics, adoptive cell therapies, vaccines (including cancer), CRISPR and other nucleic acid-
based therapies. Linear DNA does not require recombination, therefore, there is no need for a virus or for plasmids. This reduces the risk of unwanted DNA or other contaminants
that would need to be removed.

Critical Accounting Policies

Financial Reporting Release No. 60, published by the SEC, recommends that all companies include a discussion of critical accounting policies used in the preparation of their
financial statements. While all these significant accounting policies impact our financial condition and results of operations, we view certain of these policies as critical. Policies
determined to be critical are those policies that have the most significant impact on our consolidated financial statements and require management to use a greater degree of
judgment and estimates. Actual results may differ from those estimates.

We believe that given current facts and circumstances, it is unlikely that applying any other reasonable judgments or estimate methodologies would cause a material effect on our
consolidated results of operations, financial position or liquidity for the periods presented in this report.

The accounting policies identified as critical are as follows:

● Revenue recognition; and

● Equity based compensation.

44

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Revenue Recognition

We recognize revenue in accordance with Accounting Standards Codification (“ASC”) 605, Revenue Recognition (“ASC 605”). ASC 605 requires that four basic criteria must be
met before revenue can be recognized: (1) persuasive evidence of an arrangement exists; (2) delivery has occurred and/or service has been performed; (3) the selling price is fixed
and determinable; and (4) collectability is reasonably assured. Determination of criteria (3) and (4) are based on management’s judgments regarding the fixed nature of the selling
prices of the products delivered or services provided and the collectability of those amounts. Provisions for allowances and other adjustments are provided for in the same period
the related sales are recorded. We defer any revenue for which the product has not been delivered, service has not been provided, or is subject to refund until such time that we
and the customer jointly determine that the product has been delivered, the service has been provided, or no refund will be required.

Revenue arrangements with multiple components are divided into separate units of accounting if certain criteria are met, including whether the delivered component has stand-
alone value to the customer. Consideration received is allocated among the separate units of accounting based on their respective selling prices. The selling price for each unit is
based on vendor-specific objective evidence, or VSOE, if available, third party evidence if VSOE is not available, or estimated selling price if neither VSOE nor third party is
available. The applicable revenue recognition criteria are then applied to each of the units.

Revenue for government contract awards, which supports our development efforts on specific projects, is recognized as milestones are achieved as per the contract. Revenue for
firm fixed price government contract awards are recognized over the period of the contract. We recognized revenue of $748,040 and $249,348, from these contract awards during the
fiscal years ended September 30, 2018 and 2017, respectively.

45

 
 
 
 
 
 
 
 
The Company has a licensing agreement with Himatsingka that operates in the cotton industry. The shipment to this customer during June 2018 included extended payment terms,
as compared to those defined in the contract. The extended payment terms for this shipment are three equal installments due 90, 180 and 270 days from shipment. Due to the
extended payment terms, this shipment was originally recorded to deferred revenue and the deferred revenue will be recognized to revenue as the payments become due and
assuming all other conditions for revenue recognition have been satisfied. At September 30, 2018, the amount included in deferred revenue related to the shipment with extended
payment terms was $766,192. The cotton ginning season in the United States takes place between September and March each year; therefore, revenues from these customer
contracts may be seasonal and recognized primarily during the first and fourth quarters of our fiscal year.

Equity Based Compensation

We account for stock-based compensation for employees and directors in accordance with AS 718, Compensation (“ASC 718”). ASC 718 requires all share-based payments to
employees, including grants of employee stock options, to be recognized in the statement of operations based on their fair values. Under the provisions of ASC 718, stock-based
compensation costs are measured at the grant date, based on the fair value of the award, and are recognized as expense over the employee’s requisite service period (generally the
vesting period of the equity grant). The fair value of our common stock options is estimated using the Black Scholes option-pricing model with the following assumptions:
expected volatility, dividend rate, risk free interest rate and the expected life. We expense stock-based compensation by using the straight-line method. In accordance with ASC
718, excess tax benefits realized from the exercise of stock-based awards are classified as cash flows from operating activities. All excess tax benefits and tax deficiencies (including
tax benefits of dividends on share-based payment awards) are recognized as income tax expense or benefit in the condensed consolidated statements of operations. We estimate
the number of awards expected to be forfeited and adjust the estimate when it is no longer probable that the employee will fulfill the service conditions.

We account for stock-based compensation awards issued to non-employees for services, as prescribed by ASC 718-10, at either the fair value of the services rendered, or the
instruments issued in exchange for such services, whichever is more readily determinable, using the measurement date guidelines enumerated in ASC 505-50.

Use of Estimates

The preparation of the financial statements in conformity with Accounting Principles Generally Accepted in the United States (“GAAP”) requires management to make estimates
and assumptions that affect certain reported amounts and disclosures. Management bases its estimates on historical experience and on various assumptions that are believed to be
reasonable under the circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities that are not readily apparent from
other sources. The most complex and subjective estimates include recoverability of long-lived assets, including the values assigned to goodwill, intangible assets and property,
plant and equipment, fair value calculations for stock based compensation, contingencies, allowance for doubtful accounts, and management’s anticipated liquidity. Management
reviews its estimates on a regular basis and the effects of any material revisions are reflected in the consolidated financial statements in the period they are deemed necessary.
Accordingly, actual results could differ from those estimates.

Comparison of the Fiscal Year Ended September 30, 2018 to the Fiscal Year Ended September 30, 2017

Revenues

Product revenues

For the fiscal years ended September 30, 2018 and 2017, we generated $1,827,626 and $3,733,995 in revenues from product sales, respectively. The decrease in product revenues of
$1,906,369 or 51% for the fiscal year ended September 30, 2018 is attributable to a decrease in revenue of approximately $2,237,000 in the textile industry for protecting cotton and
synthetic supply chains. Decreases in the textile division were offset partially by an increase in revenue from DNA Production of $342,943.

Service revenues

For the fiscal years ended September 30, 2018 and 2017, we generated $2,075,717 and $1,017,265 in revenues from sales of services, respectively. The increase in service revenues of
$1,058,452 or 104% for the fiscal year ended September 30, 2018 is attributable to an increase in the government contract award of approximately $500,000 as well as an increase of
approximately $729,000 related to feasibility projects. This increase was comprised of $354,000 for a cannabis pilot as well as the recognition of $375,000 for pharmaceuticals. These
increases were partially offset by the completion of a fertilizer pilot of $95,000 during the prior fiscal year.

46

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Costs and Expenses

Cost of Revenues

Cost of revenues for the fiscal years ended September 30, 2018 and 2017 were $1,206,814 and $1,077,232, respectively. Cost of revenues as a percentage of product revenue were
66% and 29% for the fiscal years ended September 30, 2018 and 2017, respectively. This increase in cost of revenues as a percentage of product revenues is due to decreased sales
to the textile industry which carry higher margins. To a lesser extent, the increase of costs of revenues as a percentage of product revenues is due to lower product revenue during
the current fiscal year and therefore, our production decreased, and, as a result, our fixed production costs, primarily comprised of payroll expenses and rent and utilities allocated
to our production facilities, were not fully absorbed by product sales.

Selling, General and Administrative

Selling, general and administrative expenses for the fiscal year ended September 30, 2018 decreased by $2,281,040 or 17% to $11,043,463 from $13,324,503 in the same period in fiscal
2017. The decrease is primarily attributable to an decrease in stock based compensation expense of approximately $1,900,000, related to the recognition of expense related to certain
performance based options during the prior fiscal year, these same performance based options were cancelled during the fiscal year ended September 30, 2018; therefore, the
performance conditions were no longer probable and the options did not vest and the related expense of $415,786 was reversed during the current fiscal year. The decrease also
related to a decrease in bad debt of $403,000 as a result of the write-off of a portion of our accounts receivable during the prior fiscal year, as well as a decrease of $252,000 in legal
expenses. These decreases were offset by an increase in payroll of $298,000 primarily resulting from the accrual of the Chief Executive Officer’s bonus, offset by a reduction in
regular payroll for deferred salary accrual recorded during the fiscal third quarter.

Research and Development

Research and development expenses increased by $469,216 or 21% for the fiscal year ended September 30, 2018 compared to the same period in fiscal 2017 to $2,751,578 from
$2,282,362. The increase is primarily attributable to development costs incurred in relation the government development contract award.

47

 
 
 
 
 
 
 
 
 
 
 
Depreciation and Amortization

Depreciation and amortization decreased by $339,509 or 38% compared to the same period in 2017 from $887,305 for the fiscal year ended September 30, 2017 to $547,796 for the
fiscal year ended September 30, 2018.The decrease is attributable to impairment of approximately $253,000 of internally developed software during the fiscal year ended September
30, 2017.

Interest income (expense)

Interest income (expense) for the fiscal year ended September 30, 2018, decreased to expense of $9,615 from income of $2,763 in the same period of 2017. The decrease in interest
income was due to interest earned on the convertible notes payable for the fiscal year ended September 30, 2018.

Other (expense) income

Other (expense) income for the fiscal year ended September 30, 2018, decreased to expense of $37,005 from expense of $38,388 in the same period of 2017.

Net Loss

Net loss decreased $1,162,839, or 9% to $11,692,928 for the fiscal year ended September 30, 2018 compared to $12,855,767 for the fiscal year ended September 30, 2017 due to the
factors noted above.

Recently Issued Accounting Pronouncements

See Note B, “Recent Accounting Principles,” to the accompanying consolidated financial statements for a description of accounting standards which may impact our consolidated
financial statements in future reporting periods.

Liquidity and Capital Resources

Our liquidity needs consist of our working capital requirements and research and development expenditure funding. As of September 30, 2018, we had working capital of $1,180,185.
For the fiscal year ended September 30, 2018, we used cash in operating activities of $6,917,209 consisting primarily of our loss of $11,692,928 net with non-cash adjustments of
$547,796 in depreciation and amortization charges, $1,356,351 for stock-based compensation, $20,552 of bad debt expense and $1,479 in amortization of debt issuance costs.
Additionally, we had a net decrease in operating assets of $917,659 and a net increase in operating liabilities of $1,931,882. Cash used in investing activities was $266,008, for the
purchase of property and equipment. Cash provided by financing activities was $5,883,000, which included net proceeds from the sale of common stock and warrants related to a
private placement in December 2017 and the proceeds from the sale of senior secured convertible promissory notes during August 2018. In addition, on November 29, 2018, we
closed on senior secured convertible promissory notes that resulted in gross proceeds to us of $550,000.

We have recurring net losses, which have resulted in an accumulated deficit of $248,366,083 as of September 30, 2018. We have incurred a net loss of $11,692,928 for the fiscal year
ended September 30, 2018. At September 30, 2018, we had cash and cash equivalents of $1,659,564. These factors raise substantial doubt about the Company’s ability to continue
as a going concern for one year from the issuance of the financial statements. The ability of the Company to continue as a going concern is dependent on the Company's ability to
further implement its business plan, raise capital, and generate revenues. The financial statements do not include any adjustments that might be necessary if the Company is
unable to continue as a going concern.

Our current capital resources include cash and cash equivalents, accounts receivable and inventories. Historically, we have financed our operations principally from the sale of
equity securities. As discussed in Note G, to the accompanying consolidated financial statements, on August 31, 2018 and November 29, 2018, we closed on $1,650,000 million and
$550,000, respectively, of senior secured convertible notes by way of a private placement with accredited investors and certain members of our management team and Board of
Directors.

48

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
We expect capital expenditures to be less than $200,000 in fiscal 2019. Our primary investments will be in laboratory equipment to support prototyping, manufacturing, our
authentication services, and outside services for our detector and reader development. These capital expenditures include one-time set up costs associated with the establishment
of our laboratory space located in India.

Substantially all of the real property used in our business is leased under operating lease agreements.

Recent Debt and Equity Financing Transactions

Fiscal 2018

On December 22, 2017, we closed a securities purchase agreement with certain institutional investors for the purchase and sale of 2,735,000 shares of our common stock and
warrants to purchase an aggregate of 2,735,000 shares of common stock in a registered direct offering with aggregate gross proceeds of $4,786,250, at a combined purchase price of
$1.75 per share. The warrants will be immediately exercisable at a price of $2.00 per share of common stock and will expire five years from the date of issuance.

After deducting placement agent fees and other estimated expenses related to the registered direct offering, the aggregate net proceeds were approximately $4,200,000.

The warrants include an adjustment provision that, subject to certain exceptions, reduces their exercise price if we issue common stock or common stock equivalents at a price
lower than the then-current exercise price of the warrants, subject to a minimum exercise price of $0.44. The exercise price and number of the shares of our common stock issuable
upon the exercise of the warrants will be subject to adjustment as set forth therein (including for stock dividends and splits, reverse stock split, recapitalization, reorganization or
similar transaction). The warrants are subject to a call provision whereby we may, subject to certain provisions, including that the weighted average price of our common stock has
exceeded $5.00 for twenty consecutive trading days, call for cancellation of all or any portion of the warrants not yet exercised.

In addition, if and only if there is no effective registration statement registering, or no current prospectus available for, the resale of the warrants, the investors may exercise the
warrants by means of a “cashless exercise.”

On August 31, 2018, we entered into a securities purchase agreement with accredited investors and certain members of our management team and Board of Directors (the
“Purchaser”), pursuant to which we issued and sold an aggregate of $1,650,000 in principal amount of secured convertible notes (the “August 31st Notes”) bearing interest at a rate
of 6% per annum (the “Private Placement”). As part of the August 31st Notes, our management and Board of Directors purchased Notes with a principal amount of $1,185,000.

The August 31st Notes are convertible, in whole or in part, at any time, at the option of the Purchasers, into shares of our common stock, in an amount determined by dividing the
principal amount of each Note, together with any and all accrued and unpaid interest, by the conversion price of $2.50. We have the right to require the Purchasers to convert all or
any part of their Notes into shares of our common stock at a conversion price of $2.50 if the price of the common stock remains at a closing price of $3.50 or more for a period of
twenty consecutive trading days.

Upon any Change in Control (as defined in the August 31st Notes), the Purchasers have the right to require us to redeem the Notes, in whole or in part, at a redemption price equal
to such Notes’ outstanding principal balance plus accrued interest.

The August 31st Notes contain certain events of default that are customarily included in financing of this nature. If an event of default occurs, the Purchasers may require us to
redeem the August 31st Notes, in whole or in part, at a redemption price equal to such notes’ outstanding principal balance plus accrued interest.

The August 31st Notes bear interest at the rate of 6% per annum, payable semi-annually in cash or in kind, at our option, and are due and payable in full on August 30, 2021. Until
the principal and accrued but unpaid interest under the August 31st Notes is paid in full, or converted into shares of common stock pursuant to their terms, our obligations under
the Notes will be secured by a lien on substantially all assets of the Company (excluding certain cash accounts) and the assets of APDN (B.V.I.) Inc., the Company’s wholly-owned
subsidiary (“APDN BVI”), in favor of Delaware Trust Company, as Collateral Agent for the Purchasers pursuant to security agreements dated as of the date of the Purchase
Agreement (the “Security Agreements”).

We have also entered into a registration rights agreement, dated as of the date of the Purchase Agreement (the “Registration Rights Agreement”), with the Purchasers, pursuant to
which we have agreed to prepare and file a registration statement with the SEC to register under the Securities Act of 1933, as amended (the “Securities Act”) resales from time to
time of the common stock issued or issuable upon conversion or redemption of the Notes. We are required to file a registration statement within 60 days of receiving a demand
registration request from holders of a majority of the outstanding principal balance of the Notes, and to cause the registration statement to be declared effective within 45 days (or
90 days if the registration statement is reviewed by the SEC).

49

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
The Private Placement was completed in reliance upon the exemption from registration provided for by Section 4(a)(2) of the Securities Act and by Rule 506 of Regulation D
promulgated under the Securities Act. Each of the Purchasers represented to in the Purchase Agreement that he or she is an “accredited investor” as that term is defined in Rule
501 of Regulation D.

Fiscal 2017

On November 2, 2016, we entered into a securities purchase agreement with an institutional investor providing for the purchase of $5 million of common stock and warrants at a
combined price of $2.20 per share of common stock and warrant (the “Private Placement”). In the Private Placement, we sold 2,272,727 shares of our common stock and warrants to
purchase 2,272,727 shares of our common stock. The warrants have the same terms as our existing publicly traded warrants (APDNW) with an exercise price of $3.50 per share and
an expiration date of November 20, 2019. The offering closed on November 7, 2016.

We agreed to file a registration statement providing for the resale of these securities on Form S-3 by December 7, 2016. On December 6, 2016, we filed the Form S-3, which was
declared effective by the SEC on December 13, 2016. Upon effectiveness of the registration statement, the common stock and warrants issued in the Private Placement became
freely tradeable on The NASDAQ Capital Market under the symbols "APDN" and "APDNW", respectively.

The aggregate gross proceeds to us from the Fiscal 2017 Private Placement were $5 million before deducting the placement agents' fee and other offering expenses. As a result of
the placement agents’ fee and other offering expenses attributable to the Fiscal 2017Private Placement, the net proceeds were $4,319,863.

In connection with the closing of the Fiscal 2017 Private Placement, as partial compensation, on November 7, 2016, we granted warrants to purchase an aggregate of 68,182 shares
of our common stock to the our placement agents, Maxim Group LLC and Imperial Capital LLC (the “Placement Agent Warrants”) at an exercise price of $2.53 (115% of the public
offering price), subject to adjustment as set forth therein (including for stock dividends and splits and certain other distributions and “Fundamental Transactions,” as defined
therein). The Placement Agent Warrants will be exercisable beginning six months following the closing date of the Private Placement and terminate at 5:00 P.M. (Eastern Standard
Time) on November 7, 2021. In addition, the Placement Agent Warrants provide for cashless exercise, which the Placement Agents may elect if there is no effective registration
statement registering the resale of the shares issuable upon exercise of the Placement Agent Warrants. The number of shares of common stock that may be acquired by the
Placement Agents upon any exercise of the Placement Agent Warrants (or otherwise in respect hereof) shall be limited to the extent necessary to insure that, following such
exercise, the total number of shares of common stock then beneficially owned by the Placement Agent and its Affiliates (as defined therein) and any other Persons whose
beneficial ownership of common stock would be aggregated with the Placement Agent pursuant to the Securities Exchange Act of 1934, as amended (the “Exchange Act”), does
not exceed 9.99% of the total number of issued and outstanding shares of common stock.

On June 28, 2017 we entered into subscription agreements for a private placement of our common stock, with a group of investors, including a strategic investor which is also a key
customer and intellectual property licensee of ours as well as all of our executive officers and all members of the Board of Directors. As a result of the private placement we issued
1,025,574 shares of common stock at a price of $1.76 per share for total gross proceeds of $1,805,000. As part of the private placement, our management and Board of Directors
purchased 315,346 shares of common stock for gross proceeds of $555,000. The issuance of the Common Stock was exempt from the registration requirements of the Securities Act
of 1933 (the “Securities Act”) pursuant to Section 4(a)(2) of such Securities Act and Regulation D promulgated thereunder and such Common Stock will therefore be restricted.
Each investor gave representations that he, she or it was an “accredited investor” (as defined under Rule 501 of Regulation D) and that he, she or it is purchasing such securities
without a present view toward a distribution of the securities. In addition, there was no general solicitation conducted in connection with the offer and sale of the securities.

50

 
 
 
 
 
 
 
 
 
 
 
Subsequent Events

On November 29, 2018, we closed a securities purchase agreement with our chairman, president and chief executive officer and one member of the management team, pursuant to
which we issued and sold an aggregate of $550,000 in principal amount of secured convertible notes bearing interest at a rate of 6% per annum (the “November 29th Notes”). The
November 29th Notes are substantially similar to our August 31 Notes except with respect to maturity date. The November 29th Notes are secured on a pari passu basis with the
same Company assets as the August 31 Notes.

Product Research and Development

We anticipate spending approximately $3,000,000 for product research and development activities during the next twelve months.

Off-Balance Sheet Arrangements

We do not have any off-balance sheet arrangements.

Inflation

The effect of inflation on our revenue and operating results was not significant during the fiscal years ended September 30, 2018 and 2017.

ITEM 7A. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK.

Information requested by this Item is not applicable as we are electing scaled disclosure requirements available to Smaller Reporting Companies with respect to this Item.

ITEM 8.

FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA.

See pages F-1 through F-25 following the Exhibit Index.

ITEM 9.

CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL DISCLOSURE.

Not applicable.

ITEM 9A. CONTROLS AND PROCEDURES.

Management Report on Internal Control over Financial Reporting

Evaluation of Disclosure Controls and Procedures

Under the supervision and with the participation of our management, including, our Chief Executive Officer, along with the Chief Financial Officer, on September 30, 2018, we
conducted an evaluation of the effectiveness of the design and operation of our disclosure controls and procedures, as defined in Rules 13a-15(e) under the Exchange Act, as of
September 30, 2018. Disclosure controls and procedures are those controls and procedures designed to provide reasonable assurance that the information required to be disclosed
in our Exchange Act filings is (1) recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and forms, and (2) accumulated and
communicated to management, including our Chief Executive Officer and Chief Financial Officer, as appropriate, to allow timely decisions regarding required disclosure.

Based on that evaluation, our Chief Executive Officer and Chief Financial Officer concluded that, as of September 30, 2018, our disclosure controls and procedures were effective.

Management Report on Internal Control over Financial Reporting

Our management is responsible for establishing and maintaining adequate internal control over financial reporting, as such term is defined in Exchange Act Rules 13a-15(f) and 15d-
15(f). Our internal control over financial reporting was designed to provide reasonable assurance to our management and board of directors regarding the preparation and fair
presentation of published consolidated financial statements. Internal control over financial reporting is promulgated under the Exchange Act as a process designed by, or under
the supervision of, our principal executive and principal financial officers and effected by our board of directors, management and other personnel, to provide reasonable assurance
regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles. Internal
control over financial reporting, no matter how well designed, has inherent limitations and may not prevent or detect misstatements. Therefore, even effective internal control over
financial reporting can only provide reasonable assurance with respect to the financial statement preparation and presentation.

Our management has conducted, with the participation of our CEO and CFO, an assessment, including testing of the effectiveness, of our internal control over financial reporting
as of September 30, 2018. Management’s assessment of internal control over financial reporting was based on assessment criteria established in the 2013 Internal Control—
Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (“COSO”). Based on such evaluation, management concluded that our
internal control over financial reporting was effective as of September 30, 2018.

Changes in Internal Control over Financial Reporting

The Company utilizes an outside consulting firm to assist in the analysis of technical accounting matters, which are then reviewed by the Company’s chief financial officer and
financial reporting manager. Other than this one change, there were no additional changes in our internal control over financial reporting during the most recent fiscal quarter that
has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting.

ITEM 9B. OTHER INFORMATION.

Not applicable.

51

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ITEM 10.

DIRECTORS, EXECUTIVE OFFICERS, AND CORPORATE GOVERNANCE

ITEM 11.

EXECUTIVE COMPENSATION

Part III

ITEM 12.

SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS

ITEM 13.

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE

ITEM 14.

PRINCIPAL ACCOUNTANT FEES AND SERVICES

The information called for by Items 10, 11, 12, 13 and 14 will be included in our definitive proxy statement for the 2018 Annual Meeting of Stockholders, which will be filed with the
SEC within 120 days after September 30, 2018. The relevant portions of such definitive proxy statement are incorporated herein by reference.

ITEM 15.

EXHIBITS AND FINANCIAL STATEMENT SCHEDULES.

(a)

1.

We have filed the following documents as part of this Form 10-K:

Consolidated Financial Statements

Our consolidated financial statements at September 30, 2018 and 2017 and for the years ended September 30, 2018 and 2017, and the notes thereto, together with the report of our
independent registered public accounting firm on those consolidated financial statements, are hereby filed as part of this report beginning on page F-1.

2.

Financial Statement Schedules

All financial statement schedules have been omitted since the required information is not applicable or is not present in amounts sufficient to require submission of the schedule,
or because the information required is included in the consolidated financial statements and notes thereto.

3.

Exhibits

The information required by this item is set forth on the exhibit index that follows the signature page of this report.

52

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned,
thereunto duly authorized.

SIGNATURES

Date: December 18, 2018

APPLIED DNA SCIENCES, INC.

/s/ James A. Hayward
James A. Hayward
President and Chief Executive Officer

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of the registrant and in the

capacities and on the dates indicated.

Name

/s/ JAMES A. HAYWARD
James A. Hayward

/s/ BETH M. JANTZEN
Beth M. Jantzen

/s/ JOHN BITZER, III
John Bitzer, III

/s/ ROBERT CATELL
Robert Catell

/s/ JOSEPH D. CECCOLI
Joseph D. Ceccoli

/s/ CHARLES S. RYAN
Charles S. Ryan

/s/ YACOV A. SHAMASH
Yacov A. Shamash

/s/ SANFORD R. SIMON
Sanford R. Simon

/s/ ELIZABETH M. SCHMALZ FERGUSON
Betsy M. Schmalz Ferguson

Position

  Chief Executive Officer (Principal Executive Officer),

President, Chairman of the Board of Directors and Director

Date

  December 18, 2018

  Chief Financial Officer (Principal Financial Officer and

  December 18, 2018

Principal Accounting Officer)

  Director

  Director

  Director

  Director

  Director

  Director

  Director

53

  December 18, 2018

  December 18, 2018

  December 18, 2018

  December 18, 2018

  December 18, 2018

  December 18, 2018

  December 18, 2018

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
3.1
3.2
3.3
3.4
3.5
3.6
3.7
4.1
4.2

4.3

4.4
4.5
4.6
4.7
10.1†

10.2*

10.3

10.4

10.5†

10.6*

10.7

10.8

10.9†

10.10

10.11

The following exhibits are included as part of this Form 10-K. References to “the Company” in this Exhibit List mean Applied DNA Sciences, Inc., a Delaware corporation. 

EXHIBIT INDEX

Incorporated by Reference

Filed or
Furnished
Herewith

Exhibit
Number  

Description

  Form   Exhibit

  Certificate of Incorporation
  Certificate of Amendment of Certificate of Incorporation
  Second Certificate of Amendment of Certificate of Incorporation
  Third Certificate of Amendment of Certificate of Incorporation
  Form of Certificate of Designations of the Series A Convertible Preferred Stock
  Form of Certificate of Designations of the Series B Convertible Preferred Stock
  By-Laws
  Form of Underwriter’s Warrant to be issued to Maxim Group LLC
  Form of Senior Indenture, to be entered into between Applied DNA Sciences, Inc. and the

8-K  
8-K  
8-K  
8-K  
8-K  
8-K  
8-K  
S-1/A  
S-3

Trustee designated therein

  Form of Subordinated Indenture, to be entered into between Applied DNA Sciences, Inc.

S-3

and the Trustee designated therein

  Form of Underwriter’s Warrant
  Form of Purchase Warrant
  Form of Placement Agent Warrant issued to Maxim Group LLC
  Form of Placement Agent Warrant issued to Maxim Group LLC and Imperial Capital, LLC  
  Applied DNA Sciences, Inc. 2005 Incentive Stock Plan and form of employee stock option

agreement thereunder, as amended and restated as of January 21, 2015

  Joint Development and Marketing Agreement, dated April 18, 2007 by and between

8-K  
8-K  
8-K  
8-K  
10-K  

8-K  

Applied DNA Sciences and International Imaging Materials, Inc.

3.1
3.1
3.1
3.1
3.1
3.1
3.2
10.26
4.1

4.3

4.1
4.1
4.2
4.1
10.1

10.1

File No.
002-90539
002-90539
002-90539
002-90539
002-90539
002-90539
002-90539
333-199121  
333-202432  

  Date Filed    
1/16/2009
6/30/2010
1/30/2012
10/29/2014
11/29/2012
7/22/2013
1/16/2009
10/30/2014
3/2/2015

333-202432  

3/2/2015

001-36745
001-36745
001-36745
001-36745
001-36745

3/27/2015
11/23/2015
11/23/2015
11/2/2016
12/14/2015

002-90539

4/24/2007

  Form of Subscription Agreement, dated July 15, 2011, by and among Applied DNA

10-K  

10.28

002-90539

12/9/2011

Sciences, Inc. and the investors named on the signature pages thereto

  Form of Warrant, dated July 15, 2011, issued to the investors named on the signature

10-K  

10.29

002-90539

12/9/2011

pages

  Employment Agreement, dated July 1, 2017, between James A. Hayward and Applied

DNA Sciences, Inc.

  Exclusive Sales Agreement dated November 1, 2011 by and between Applied DNA

Sciences, Inc. and Nissha Printing Co., Ltd.

8-K  

10-Q  

  Software Distribution Agreement, dated as of January 25, 2012, by and between Applied

10-Q  

DNA Sciences, Inc. and DivineRune, Inc.

10.1

10.1

10.1

001-36745

8/2/2016

002-90539

2/14/2012

002-90539

5/15/2012

  Form of Subscription Agreement dated June 21, 2012, by and among Applied DNA

10-K  

10.37

002-90539

12/20/2012

Sciences, Inc. and the investor named on the signature page thereto

  Form of Indemnification Agreement dated as of September 7, 2012, by and between

8-K  

Applied DNA Sciences, Inc. and each of its directors and executive officers

  Asset Purchase Agreement dated May 10, 2013, between Applied DNA Sciences, Inc.

10-Q  

and RedWeb Technologies Limited

  Agreement of Lease dated June 14, 2013, between Applied DNA Sciences, Inc. and Long

10-Q  

Island High Technology Incubator, Inc.

10.12*
10.13
10.14
10.15
10.16
10.17

  Term sheet for Mutual Cooperation with Borealis AG dated March 31, 2014
  Form of Subscription Agreement dated June 3, 2014
  Form of Warrant dated June 3, 2014
  Form of Award/Contract issued by U.S. Missile Defense Agency dated July 14, 2014
  Form of Promissory Note
  Form of Award/Contract awarded by Office of Secretary of Defense on behalf of Defense

8-K/A  
8-K  
8-K  
8-K  
8-K  
8-K/A  

Logistics Agency dated August 28, 2014

54

10.1

10.1

10.2

10.1
10.1
10.2
10.1
10.1
10.1

002-90539

9/13/2012

002-90539

8/13/2013

002-90539

8/13/2013

002-90539
002-90539
002-90539
002-90539
002-90539
002-90539

7/22/2014
6/6/2014
6/6/2014
7/18/2014
9/17/2014
9/8/2014

 
 
 
  
 
   
 
 
 
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
   
 
 
 
10.18

10.19

10.20

10.21

10.22

10.23*

10.24

10.25**

10.26

10.27
10.28

10.29
10.30
10.31
10.32
10.33
10.34
10.35
10.36
10.37
10.38
10.39
10.40
10.41
10.42
10.43
10.44
10.45
21.1
23.1
31.1

31.2

32.1

32.2

Exhibit
Number  

Description

  Warrant Repurchase Option Agreement dated October 28, 2014 between Applied DNA

Sciences, Inc. and Crede CG III, Ltd.

Incorporated by Reference

Filed or
Furnished
Herewith

  Form   Exhibit
10.28

S-1/A  

File No.

333-199121  

  Date Filed  
10/30/2014

  Letter Agreement dated November 11, 2014 between Applied DNA Sciences, Inc. and

S-1/A  

10.29

333-199121  

11/12/2014

James A. Hayward regarding Exchange of 12.5% Promissory Note

  Underwriting agreement between Applied DNA Sciences, Inc. and Maxim Group LLC

S-1/A  

1.1

333-199121  

11/12/2014

dated November 17, 2014

  Form of Warrant Agreement between Applied DNA Sciences, Inc. and American Stock

S-1/A  

10.25

002-90539

11/12/2014

Transfer & Trust Company, LLC, as warrant agent

  First Amendment to Warrant Agreement dated April 1, 2015 between Applied DNA
Sciences, Inc. and American Stock Transfer & Trust Company, LLC as warrant agent
  Mutual License Agreement dated March 25, 2015 between Applied DNA Sciences, Inc.

and Divatex Home Fashion, Inc.

8-K  

4.1

001-36745

4/1/2015

10-Q  

10.1

001-36745

5/11/2015

  Underwriting Agreement dated March 27, 2015, between Applied DNA Sciences, Inc. and
Maxim Group LLC, as representative of the underwriters named on Schedule A thereto.
  Asset Purchase Agreement dated September 11, 2015 between Applied DNA Sciences,

8-K  

8-K  

Inc. and Vandalia Research, Inc.

  Placement Agency Agreement by and between Applied DNA Sciences, Inc. and Maxim

8-K/A  

Group LLC, dated November 23, 2015
  Form of Securities Purchase Agreement
  Placement Agency Agreement between Maxim Group LLC, Imperial Capital, LLC and

Applied DNA Sciences, Inc. dated November 2, 2016
  Securities Purchase Agreement dated November 2, 2016
  Registration Rights Agreement dated November 2, 2016
  Second Amendment to Warrant Agreement dated November 2, 2016
  Form of Subscription Agreement
  Form of Convertible Note
  Registration Rights Agreement, dated November 29, 2018
  Securities Purchase Agreement, dated November 29, 2018
  Form of Convertible Note
  Registration Rights Agreement, dated August 31, 2018
  Securities Purchase Agreement, dated August 31, 2018
  Collateral Agency Agreement dated October 19, 2018
  Security Agreement dated October 19, 2018
  First Amendment to Security Agreement dated November 26, 2018
  Guaranty and Security Agreement dated October 19, 2018
  Intellectual Property Security Agreement dated October 19, 2018
  Intellectual Property Security Agreement dated October 19, 2018
  Securities Purchase Agreement, dated August 31, 2018
  Subsidiaries of Applied DNA Sciences, Inc.
  Consent of Marcum LLP
  Certification of Chief Executive Officer, pursuant to Rules 13a-14(a) and 15d-14(a) of the
Securities Exchange Act of 1934, as amended, as adopted pursuant to Section 302 of the
Sarbanes-Oxley Act of 2002

  Certification of Chief Financial Officer, pursuant to Rules 13a-14(a) and 15d-14(a) of the
Securities Exchange Act of 1934, as amended, as adopted pursuant to Section 302 of the
Sarbanes-Oxley Act of 2002

  Certification of Chief Executive Officer, pursuant to 18 U.S.C. Section 1350, as adopted

pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

  Certification of Chief Financial Officer, pursuant to 18 U.S.C. Section 1350, as adopted

101 INS
101 SCH
101 CAL
101 DEF
101 LAB
101 PRE

pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

  XBRL Instance Document
  XBRL Taxonomy Extension Schema Document
  XBRL Taxonomy Extension Calculation Linkbase Document
  XBRL Taxonomy Extension Definitions Linkbase Document
  XBRL Taxonomy Extension Labels Linkbase Document
  XBRL Taxonomy Extension Presentation Linkbase Document

† Indicates a management contract or any compensatory plan, contract or arrangement.

1.1

2.1

10.1

10.2
10.1

10.2
10.3
10.4
10.1
10.1
10.2
10.3
10.1
10.2
10.3

001-36745

3/27/2015

001-36745

9/17/2015

001-36745

11/23/2015

001-36745
001-36745

001-36745
001-36745
001-36745
001-36745
001-36745
001-36745
001-36745
001-36745
001-36745
001-36745

11/23/2015
11/2/2016

11/2/2016
11/2/2016
11/2/2016
6/28/2017
12/6/2018
12/6/2018
12/6/2018
12/10/2018
12/10/2018
12/10/2018

8-K/A  
8-K  

8-K  
8-K  
8-K  
8-K  
8-K  
8-K  
8-K  
  8-K/A  
  8-K/A  
  8-K/A  

S-1/A  

21.1

333-199121  

10/30/2014

Filed
Filed
Filed
Filed
Filed
Filed
Filed

Filed
Filed

Filed

Filed

Filed

Filed
Filed
Filed
Filed
Filed
Filed

* A request for confidentiality has been granted for certain portions of the indicated document. Confidential portions have been omitted and filed separately with the SEC as
required by Rule 24b-2 promulgated under the Exchange Act.

** Schedules (or similar attachments) have been omitted pursuant to Item 601(b)(2) of Regulation S-K. Applied DNA Sciences, Inc. agrees to furnish supplementally a copy of any
such omitted schedule or attachment to the U.S. Securities and Exchange Commission upon request; provided, however, that Applied DNA Sciences, Inc. may request confidential
treatment pursuant to Rule 24b-2 under the Exchange Act for any schedule or attachment so furnished.

55

 
  
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
 
   
   
   
   
 
   
   
   
   
 
   
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
INDEX TO FINANCIAL STATEMENTS

Report of Independent Registered Public Accounting Firm

Consolidated Balance Sheets as of September 30, 2018 and 2017

Consolidated Statements of Operations for the Years Ended September 30, 2018 and 2017

Consolidated Statements of Stockholders’ Equity for the Years Ended September 30, 2018 and 2017

Consolidated Statements of Cash Flows for the Years Ended September 30, 2018 and 2017

Notes to Consolidated Financial Statements

F-1

Page

F-2

F-3

F-4

F-5

F-6

F-7

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Stockholders and Board of Directors of
Applied DNA Sciences, Inc.

Opinion on the Financial Statements

We have audited the accompanying consolidated balance sheets of Applied DNA Sciences, Inc. (the “Company”) as of September 30, 2018 and 2017, the related consolidated
statements of operations, stockholders’ equity and cash flows for each of the two years in the period ended September 30, 2018, and the related notes (collectively referred to as
the “financial statements”). In our opinion, the financial statements present fairly, in all material respects, the financial position of the Company as of September 30, 2018 and 2017,
and the results of its operations and its cash flows for each of the two years in the period ended September 30, 2018, in conformity with accounting principles generally accepted in
the United States of America.

Explanatory Paragraph – Going Concern

The accompanying consolidated financial statements have been prepared assuming that the Company will continue as a going concern. As more fully described in Note A, the
Company has incurred significant losses and needs to raise additional funds to meet its obligations and sustain its operations. These conditions raise substantial doubt about the
Company's ability to continue as a going concern. Management's plans in regard to these matters are also described in Note A. The consolidated financial statements do not
include any adjustments that might result from the outcome of this uncertainty.

Basis for Opinion

These financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on the Company's financial statements based on our
audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) ("PCAOB") and are required to be independent with
respect to the Company in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audits to obtain reasonable assurance about
whether the financial statements are free of material misstatement, whether due to error or fraud. The Company is not required to have, nor were we engaged to perform, an audit of
its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of
expressing an opinion on the effectiveness of the Company's internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements, whether due to error or fraud, and performing procedures that
respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements. Our audits also included
evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements. We believe
that our audits provide a reasonable basis for our opinion.

/s/ Marcum llp

Marcum llp

We have served as the Company’s auditor since 2014.

Melville, NY 
December 18, 2018

F-2

 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
CONSOLIDATED BALANCE SHEETS
SEPTEMBER 30, 2018 AND 2017

ASSETS

Current assets:
Cash and cash equivalents
Accounts receivable, net of allowance of $13,133 and $10,000 at September 30, 2018 and 2017, respectively
Inventories
Prepaid expenses and other current assets
Total current assets

Property and equipment, net

Other assets:
Deposits
Goodwill

Intangible assets, net

Total Assets

LIABILITIES AND STOCKHOLDERS’ EQUITY

Current liabilities:
Accounts payable and accrued liabilities (including related party of $5,844 at September 30, 2018)
Deferred revenue
Total current liabilities

Long term accrued liabilities
Secured convertible notes payable, net of debt issuance costs (including related party of $1,139,490 at September 30, 2018)

Total liabilities

Commitments and contingencies

Stockholders’ Equity:
Preferred stock, par value $0.001 per share; 10,000,000 shares authorized; -0- shares issued and outstanding as of September 30, 2018
and 2017
Series A Preferred stock, par value $0.001 per share; 10,000,000 shares authorized; -0- issued and outstanding as of September 30,
2018 and 2017
Series B Preferred stock, par value $0.001 per share; 10,000,000 shares authorized; -0- issued and outstanding as of September 30,
2018 and 2017

Common stock, par value $0.001 per share; 500,000,000 shares authorized; 30,112,057 and 27,377,057 shares issued and outstanding
as of September 30, 2018 and 2017, respectively
Additional paid in capital
Accumulated deficit

Total stockholders’ equity

Total Liabilities and Stockholders’ Equity

See the accompanying notes to the consolidated financial statements

F-3

  $

September 30,

2018

2017

1,659,564    $
1,485,938     
221,369     
635,174     
4,002,045     

2,959,781 
2,587,969 
326,468 
366,954 
6,241,172 

419,774     

523,688 

62,325     
285,386     

61,626 
285,386 

864,203     

1,042,076 

  $

5,633,733    $

8,153,948 

  $

965,167    $
1,856,693     
2,821,860     

470,739     
1,586,631     

944,133 
351,735 
1,295,868 

- 
- 

4,879,230     

1,295,868 

-     

-     

-     

- 

- 

- 

30,112     
249,090,474     
(248,366,083)    

27,377 
243,503,858 
(236,673,155)

754,503     

6,858,080 

  $

5,633,733    $

8,153,948 

 
 
 
 
 
 
 
 
   
 
   
      
  
   
      
  
   
   
   
   
 
   
      
  
   
 
   
      
  
   
      
  
   
   
 
   
      
  
   
 
   
      
  
 
   
      
  
   
      
  
 
   
      
  
   
      
  
   
   
 
   
      
  
   
   
 
   
      
  
   
 
   
      
  
   
      
  
 
   
      
  
   
      
  
   
   
   
 
   
      
  
   
   
   
 
   
      
  
   
 
   
      
  
 
 
 
 
APPLIED DNA SCIENCES, INC.
CONSOLIDATED STATEMENTS OF OPERATIONS
YEARS ENDED SEPTEMBER 30, 2018 AND 2017

Revenues:

Product revenues
Service revenues

Total revenues

Cost of revenues

Operating expenses:
Selling, general and administrative
Research and development
Depreciation and amortization

Total operating expenses

LOSS FROM OPERATIONS

Other (expense) income:
Interest (expense) income, net (including related party interest of $5,844 for the year ended September 30, 2018)
Other expense, net

Loss before provision for income taxes

Provision for income taxes

NET LOSS

Net loss per share-basic and diluted

Weighted average shares outstanding-basic and diluted

See the accompanying notes to the consolidated financial statements

F-4

2018

2017

  $

1,827,626    $
2,075,717     

3,733,995 
1,017,265 

3,903,343     

4,751,260 

1,206,814     

1,077,232 

11,043,463     
2,751,578     
547,796     

13,324,503 
2,282,362 
887,305 

14,342,837     

16,494,170 

(11,646,308)    

(12,820,142)

(9,615)    
(37,005)    

2,763 
(38,388)

(11,692,928)    

(12,855,767)

-     

- 

(11,692,928)   $

(12,855,767)

(0.40)   $

(0.49)

29,497,619     

26,378,991 

  $

  $

 
 
 
 
 
   
 
   
      
  
 
   
      
  
   
 
   
      
  
   
 
   
      
  
   
 
   
      
  
   
      
  
   
   
   
 
   
      
  
   
 
   
      
  
   
 
   
      
  
   
      
  
   
   
 
   
      
  
   
 
   
      
  
   
 
   
      
  
 
   
      
  
 
   
      
  
   
 
 
 
 
APPLIED DNA SCIENCES, INC.
CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY
YEARS ENDED SEPTEMBER 30, 2018 and 2017

Common
Shares

Common
Stock
Amount

Additional
Paid in
Capital

Balance, October 1, 2016
Common stock issued for consulting services
Shares issued in underwritten public offerings, net of offering
costs
Stock based compensation expense
Net loss
Balance, September 30, 2017
Common stock issued in private placement, net of offering
costs
Stock based compensation expense
Net loss
Balance, September 30, 2018

24,078,756    $
1,025,574     

2,272,727     
—     
—     
27,377,057    $

2,735,000     
—     
—     
30,112,057    $

24,079    $
1,025     

2,273     
—     
—     
27,377    $

2,735     
—     
—     
30,112    $

234,158,711    $
1,770,252     

4,317,590     
3,257,305     
—     
243,503,858    $

4,230,265     
1,356,351     
—     
249,090,474    $

See the accompanying notes to the consolidated financial statements

F-5

Accumulated
Deficit
(223,817,388)   $
—     

—     
—     
(12,855,767)    
(236,673,155)   $

—     
—     
(11,692,928)    
(248,366,083)   $

Total

10,365,402 
1,771,277 

4,319,863 
3,257,305 
(12,855,767)
6,858,080 

4,233,000 
1,356,351 
(11,692,928)
754,503 

 
 
 
 
 
   
   
   
   
 
   
   
   
   
   
   
   
   
   
   
 
 
 
 
APPLIED DNA SCIENCES, INC.
CONSOLIDATED STATEMENT OF CASH FLOWS
YEARS ENDED SEPTEMBER 30, 2018 AND 2017

Cash flows from operating activities:
Net loss
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization
Impairment expense
Stock based compensation expense
Amortization of debt issuance costs
Provision for bad debts
Change in operating assets and liabilities:
Accounts receivable
Inventories
Prepaid expenses, other current assets and deposits
Accounts payable and accrued liabilities
Deferred revenue
Net cash used in operating activities

Cash flows from investing activities:
Purchases of property and equipment
Net cash used in investing activities

Cash flows from financing activities:

Net proceeds from sale of common stock and warrants
Net proceeds from secured convertible promissory notes (including related party of $1,185,000 for the year ended September 30,

2018)

Net cash provided by financing activities

Net decrease in cash and cash equivalents
Cash and cash equivalents at beginning of year
Cash and cash equivalents at end of year

Supplemental Disclosures of Cash Flow Information:
Cash paid during year for interest
Cash paid during year for income taxes

Non-cash investing and financing transactions:
Debt issuance costs included in accounts payable and accrued liabilities
Reclassification of deferred offering costs to additional paid in capital

See the accompanying notes to the consolidated financial statements

F-6

2018

2017

  $

(11,692,928)   $

(12,855,767)

547,796     
-     
1,356,351     
1,479     
20,552     

1,081,480     
105,099     
(268,920)    
426,924     
1,504,958     
(6,917,209)    

633,328 
253,977 
3,257,305 
- 
423,920 

3,084,311 
(28,709)
(167,448)
(610,504)
(1,469,597)
(7,479,184)

(266,008)    
(266,008)    

(145,436)
(145,436)

4,233,000     

6,105,127 

1,650,000     
5,883,000     

(1,300,217)    
2,959,781     
1,659,564    $

- 
6,105,127 

(1,519,493)
4,479,274 
2,959,781 

-    $
-    $

- 
- 

64,848    $
-    $

- 
13,986 

  $

  $
  $

  $
  $

 
 
 
 
 
   
 
   
      
  
   
      
  
   
   
   
   
   
   
      
  
   
   
   
   
   
   
 
   
      
  
   
      
  
   
   
 
   
      
  
   
      
  
 
   
      
  
   
   
   
 
   
      
  
   
   
 
   
      
  
   
      
  
 
   
      
  
   
      
  
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE A – LIQUIDITY AND MANAGEMENT’S PLAN

Applied DNA Sciences, Inc. (the “Company”) has recurring net losses, which have resulted in an accumulated deficit of $248,366,083 as of September 30, 2018. The Company
incurred a net loss of $11,692,928 and generated negative operating cash flow of $6,917,209 for the fiscal year ended September 30, 2018. At September 30, 2018 the Company had
cash and cash equivalents of $1,659,564 and working capital of $1,180,185. These factors raise substantial doubt about the Company’s ability to continue as a going concern for
one year from the issuance of the financial statements. The ability of the Company to continue as a going concern is dependent on the Company's ability to further implement its
business plan, raise capital, and generate revenues. The Financial Statements do not include any adjustments that might be necessary if the Company is unable to continue as a
going concern.

The Company’s current capital resources include cash and cash equivalents, accounts receivable and inventories. Historically, the Company has financed its operations principally
from the sale of equity securities.

NOTE B – SUMMARY OF ACCOUNTING POLICIES

Business and Basis of Presentation

On September 16, 2002, the Company was incorporated under the laws of the State of Nevada. Effective December 2008, the Company reincorporated from the State of Nevada to
the State of Delaware. The Company is principally devoted to developing and marketing plant-based or other DNA technology solutions in the United States, Europe and Asia. To
date, the Company has produced limited recurring revenues from its products and services; it has incurred expenses and has sustained losses. Consequently, its operations are
subject to all the risks inherent in the establishment of a biotechnology company.

The  consolidated  financial  statements  include  the  accounts  of  the  Company  and  its  wholly-owned  subsidiaries, APDN  (B.V.I.)  Inc., Applied  DNA  Sciences  Europe  Limited,
Applied DNA Sciences India Private Limited and LineaRx, Inc. (“LRx”). Applied DNA Sciences India Private Limited was incorporated in India on June 22, 2018 and LineaRx, Inc.
was incorporated in  Delaware on  September 11, 2018.  Significant inter-company transactions and balances have been eliminated in consolidation.  To facilitate comparison of
information across periods, certain reclassifications have been made to prior year amounts to conform to the current year’s presentation.

Use of Estimates

The  preparation  of  the  financial  statements  in  conformity  with Accounting  Principles  Generally Accepted  in  the  U.S.  (“GAAP”)  requires  management  to  make  estimates  and
assumptions that affect certain reported amounts and disclosures. Management bases its estimates on historical experience and on various assumptions that are believed to be
reasonable under the circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities that are not readily apparent from
other sources. The most complex and subjective estimates include recoverability of long-lived assets, including the values assigned to goodwill, intangible assets and property
and  equipment,  fair  value  calculations  for  stock  based  compensation,  contingencies,  allowance  for  doubtful  accounts  and  management’s  anticipated  liquidity.  Management
reviews its estimates on a regular basis and the effects of any material revisions are reflected in the consolidated financial statements in the period they are deemed necessary.
Accordingly, actual results could differ from those estimates.

F-7

 
 
 
 
 
 
 
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE B – SUMMARY OF ACCOUNTING POLICIES, continued

Revenue Recognition

The Company recognizes revenue in accordance with Accounting Standards Codification (“ASC”) 605, Revenue Recognition (“ASC 605”). ASC 605 requires that four basic criteria
must be met before revenue can be recognized: (1) persuasive evidence of an arrangement exists; (2) delivery has occurred and/or service has been performed; (3) the selling price
is fixed and determinable; and (4) collectability is reasonably assured. Determination of criteria (3) and (4) are based on management’s judgments regarding the fixed nature of the
selling prices of the products delivered or services provided and the collectability of those amounts. Provisions for allowances and other adjustments are provided for in the same
period the related sales are recorded. The Company defers any revenue for which the product has not been delivered, service has not been provided, or is subject to refund until
such time that the Company and the customer jointly determine that the product has been delivered, the service has been provided, or no refund will be required. At September 30,
2018 and 2017, the Company recorded total deferred revenue of $1,856,693 and $351,735, respectively.

Revenue arrangements with multiple components are divided into separate units of accounting if certain criteria are met, including whether the delivered component has stand-
alone value to the customer. Consideration received is allocated among the separate units of accounting based on their respective selling prices. The selling price for each unit is
based on vendor-specific objective evidence, or VSOE, if available, third party evidence if VSOE is not available, or estimated selling price if neither VSOE nor third party evidence
is available. The applicable revenue recognition criteria are then applied to each of the units.

Revenue for government contract awards, which supports the Company’s development efforts on specific projects, is recognized as firm fixed price government contract awards
and are recognized over the period of the contract. The Company recognized revenue from a government contract of $748,040 and $249,348 for the fiscal years ended September 30,
2018 and 2017, respectively.

The Company has a licensing agreement with a company that operates in the cotton industry. The shipment to this customer during fiscal 2018 included extended payment terms,
as compared to those defined in the contract and therefore is included in deferred revenue as of September 30, 2018. The extended payment terms for this shipment are three equal
installments due 90, 180 and 270 days from shipment. The deferred revenue will be recognized to revenue as the payments become due assuming all other conditions for revenue
recognition have been satisfied. At September 30, 2018, the amount included in deferred revenue related to the shipment with extended payment terms was $766,192. The cotton
ginning season in the United States takes place between September and March each year; therefore, revenues from our cotton customer contracts may be seasonal and recognized
primarily during our first and fourth fiscal quarters.

Cash Equivalents

For the purpose of the accompanying consolidated financial statements, all highly liquid investments with a maturity of three months or less are considered to be cash equivalents.

Accounts Receivable

The Company provides an allowance for doubtful accounts equal to the estimated uncollectible amounts. The Company’s estimate is based on historical collection experience and
a review of the current status of trade accounts receivable. It is reasonably possible that the Company’s estimate of the allowance for doubtful accounts may change.

Trade accounts receivable are recorded at the invoiced amount and do not bear interest. The Company classifies receivable amounts as current or long-term based on expected
payment and records long-term accounts receivable when the collection period is expected to be greater than one year.

At September 30, 2018 and 2017, the Company has an allowance for doubtful accounts of $13,133 and $10,000, respectively. The Company writes-off receivables that are deemed
uncollectible.

F-8

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE B – SUMMARY OF ACCOUNTING POLICIES, continued

Inventories

Inventories, which consist primarily of raw materials and finished goods, are stated at the lower of cost or net realizable value, which cost determined by using the first-in, first-out
(FIFO) method.

Income Taxes

The Company accounts for income taxes in accordance with ASC 740, Income Taxes (“ASC 740-10”) which requires the recognition of deferred tax liabilities and assets for the
expected future tax consequences of events that have been included in the financial statement or tax returns. Under this method, deferred tax liabilities and assets are determined
based on the difference between financial statements and tax basis of assets and liabilities using enacted tax rates in effect for the year in which the differences are expected to
reverse. Temporary differences between taxable income reported for financial reporting purposes and income tax purposes include, but not limited to, accounting for intangibles,
equity based compensation and depreciation and amortization. The Company evaluates the recoverability of deferred tax assets and establishes a valuation allowance when it is
more likely than not that some portion or all of the deferred tax asset will not be realized. During the fiscal years ended September 30, 2018 and 2017, the Company incurred losses
from operations. Based upon these results and the trends in the Company’s performance projected for fiscal year 2019, it is more likely than not that the Company will not realize
any benefit from the deferred tax assets recorded by the Company in previous periods. Management makes judgments as to the interpretation of tax laws that might be challenged
upon an audit and cause changes to previous estimates of tax liability. In management’s opinion, adequate provisions for income taxes have been made for all years. If actual
taxable income by tax jurisdiction varies from estimates, additional allowances or reversals of reserves may be necessary. The Company has identified its federal tax return and its
state tax return in New York as “major” tax jurisdictions. Based on the Company’s evaluation, it has been concluded that there are no significant uncertain tax positions requiring
recognition in the Company’s consolidated financial statements.

The Company believes that its income tax positions and deductions will be sustained on audit and does not anticipate any adjustments that will result in a material change to its
financial position. It is the Company’s policy to accrue interest and penalties on unrecognized tax benefits as components of income tax provision. The Company did not have any
accrued interest or penalties as of September 30, 2018 and 2017. Tax years 2014 through 2017 remain subject to future examination by the applicable taxing authorities.

On December 22, 2017, the U.S. government enacted comprehensive tax legislation commonly referred to as the Tax Cuts and Jobs Act (the “Tax Act”). The Tax Act makes broad
and complex changes to the U.S. tax code that will affect the Company’s fiscal year ending September 30, 2018, including, but not limited to, reducing the U.S. federal corporate tax
rate.  The  Tax Act reduces the federal corporate tax rate to 21% in the fiscal year ending  September 30, 2018. As the  Company has a  September 30 fiscal year-end, the lower
corporate income tax rate will be phased in, resulting in a U.S. federal statutory rate of approximately 24.3% for fiscal 2018 and a 21% U.S. federal statutory rate for subsequent fiscal
years. The reduction of the corporate tax rate caused the Company to reduce its deferred tax asset to the lower federal base rate of 21% and the Company adjusted the valuation
allowance against the deferred tax asset by the same amount, this also resulted in a decrease to the deferred tax asset and valuation allowance of $6,865,546. The Company has a
full allowance against the deferred tax asset and as a result there was no impact to income tax expense for the twelve month period ended September 30, 2018. The Tax Act imposes
a one-time transition tax that requires companies to increase U.S. taxable income for accumulated foreign subsidiary earnings not previously subject to U.S. income tax at a rate of
15.5% to the extent of foreign cash and certain other net current assets and 8% on the remaining earnings. As the foreign subsidiaries of the Company have a cumulative net deficit
position, there is no impact for this transition tax.

Property and Equipment

Property and equipment are stated at cost and depreciated using the straight line method over their estimated useful lives. The estimated useful life for computer equipment, lab
equipment and furniture is 3 years and leasehold improvements are amortized over the shorter of their useful life or the lease terms. Property and equipment consist of:

Computer equipment
Lab equipment
Furniture
Leasehold improvements

Total

Accumulated depreciation
Property and equipment, net

September 30,

2018

135,621    $
1,951,955     
74,781     
293,672     
2,456,029     
2,036,255     
419,774    $

2017

85,413 
1,770,407 
44,592 
289,573 
2,189,985 
1,666,297 
523,688 

  $

  $

Depreciation expense for the fiscal years ended September 30, 2018 and 2017 were $369,924 and $403,482, respectively.

F-9

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
   
   
   
   
   
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE B – SUMMARY OF ACCOUNTING POLICIES, continued

Impairment of Long-Lived Assets

The Company evaluates its long lived assets for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable.
Events relating to recoverability may include significant unfavorable changes in business conditions, recurring losses, or a forecasted inability to achieve break-even operating
results over an extended period. The Company evaluates the recoverability of long-lived assets based upon forecasted undiscounted cash flows. Should impairment in value be
indicated, the carrying value of long-lived assets will be adjusted, based on estimates of future discounted cash flows resulting from the use and ultimate disposition of the asset.
For  the  fiscal  year  ended  September  30,  2017,  the  Company  recorded  an  impairment  charge  of  $253,977,  as  determined  by  non-recurring  Level  3  inputs,  related  to  capitalized
software which is included in depreciation and amortization expense in the consolidated statements of operations.

Net Loss per Share

The Company presents loss per share utilizing a dual presentation of basic and diluted loss per share. Basic loss per share includes no dilution and has been calculated based
upon the weighted average number of common shares outstanding during the period. Dilutive common stock equivalents consist of shares issuable upon the exercise of the
Company’s stock options and warrants.

For the fiscal years ended September 30, 2018 and 2017, common stock equivalent shares are excluded from the computation of the diluted loss per share as their effect would be
anti-dilutive.

Securities that could potentially dilute basic net income per share in the future that were not included in the computation of diluted net loss per share because to do so would have
been antidilutive for the fiscal years ended September 30, 2018 and 2017 are as follows:

Warrants
Options

Stock-Based Compensation

2018
12,208,527     
6,183,214     
18,391,741     

2017
9,540,455 
5,333,227 
14,873,682 

The Company accounts for stock-based compensation for employees and directors in accordance with ASC 718, Compensation (“ASC 718”). ASC 718 requires all share-based
payments to employees, including grants of employee stock options, to be recognized in the statement of operations based on their fair values. Under the provisions of ASC 718,
stock-based compensation costs are measured at the grant date, based on the fair value of the award, and are recognized as expense over the employee’s requisite service period
(generally the vesting period of the equity grant). The fair value of the Company’s common stock options is estimated using the Black Scholes option-pricing model with the
following assumptions: expected volatility, dividend rate, risk free interest rate and the expected life. The Company expenses stock-based compensation by using the straight-line
method. In accordance with ASC 718, excess tax benefits realized from the exercise of stock-based awards are classified in cash flows from operating activities. All excess tax
benefits and tax deficiencies (including tax benefits of dividends on share-based payments awards) are recognized as income tax expense or benefit in the consolidated statement
of operations. The Company estimates the number of awards expected to be forfeited and adjusts the estimate when it is no longer probable that the employee will fulfill the service
conditions.

The Company accounts for stock-based compensation awards issued to non-employees for services, as prescribed by ASC 718-10, at either the fair value of the services rendered
or the instruments issued in exchange for such services, whichever is more readily determinable, using the measurement date guidelines enumerated in ASC 505-50.

Concentrations

Financial instruments and related items, which potentially subject the Company to concentrations of credit risk, consist primarily of cash, cash equivalents and trade receivables.
The Company places its cash and temporary cash investments with high credit quality institutions. At times, such investments may be in excess of the FDIC insurance limit.

The Company’s revenues earned from sale of products and services for the fiscal year ended September 30, 2018 include 24%, 16%, 14% and 11%, respectively from four customers
of the Company’s total revenues. These customers accounted for approximately 96% of the Company’s total accounts receivable at September 30, 2018. At September 30, 2018, one
customer accounted for an aggregate of 82% of the Company’s total accounts receivable.

F-10

 
 
 
 
 
 
 
 
 
 
 
 
   
 
   
   
 
   
 
 
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE B – SUMMARY OF ACCOUNTING POLICIES, continued

The  Company’s  revenues  earned  from  sale  of  products  and  services  for  the  fiscal  years  ended  September  30,  2017  include  29%,  26%,  13%  and  10%,  respectively  from  four
customers of the Company’s total revenues. These customers accounted for approximately 97% of the Company’s total accounts receivable at September 30, 2017. At September
30, 2017, one customer accounted for an aggregate of 80% of the Company’s total accounts receivable.

Research and Development

The  Company  accounts  for  research  and  development  costs  in  accordance  with  the ASC  730,  Research  and  Development  (“ASC  730”).  Under ASC  730,  all  research  and
development costs must be charged to expense as incurred. Accordingly, internal research and development costs are expensed as incurred. Third-party research and development
costs are expensed when the contracted work has been performed or as milestone results have been achieved. Company-sponsored research and development costs related to
both present and future products are expensed in the period incurred. During the fiscal years ended September 30, 2018 and 2017, the Company incurred research and development
expenses of $2,751,578 and $2,282,362, respectively.

Advertising

The Company follows the policy of charging the costs of advertising to expense as incurred. The Company charged to operations $287,156 and $315,266, as advertising costs for
the fiscal years ended September 30, 2018 and 2017, respectively.

Goodwill and Other Intangible Assets

The Company amortizes its intangible assets using the straight-line method over their estimated period of benefit. All of the Company’s intangible assets, except for goodwill are
subject to amortization.

Goodwill arises as a result of business acquisitions. Goodwill consists of the excess of the cost of the acquisitions over the tangible and intangible assets acquired and liabilities
assumed.

The Company evaluates goodwill for impairment at least annually. The Company qualitatively and quantitatively determines whether, more likely than not, the fair value exceeds
the carrying amount of a reporting unit. There are numerous assumptions and estimates underlying the quantitative assessments including future earnings, long-term strategies,
and  the  Company’s  annual  planning  and  forecasts.  If  these  planned  initiatives  do  not  accomplish  the  targeted  objectives,  the  assumptions  and  estimates  underlying  the
quantitative assessments could be adversely affected and have a material effect upon the Company’s financial condition and results of operations. As of September 30, 2018 and
2017, the Company performed its assessment of goodwill and indicated that there was no impairment.

Internally Developed Software

Internally developed software products, consist of capitalized costs associated with the development of computer software to be sold, leased or otherwise marketed. Software
development costs associated with new products are expensed as incurred until technological feasibility, as defined in FASB ASC Topic 985-20, has been established. Costs
incurred thereafter are capitalized until the product is made generally available. The stage during the Company’s development process for a new product or new release at which
technological feasibility requirements are established affects the amount of costs capitalized. Annual amortization of internally developed software products is the greater of the
amount computed using the ratio that current gross revenues for a product bear to the total of current and anticipated future gross revenues for that product or the straight-line
method over the remaining estimated economic life of the software product, generally estimated to be 3 years from the date the product became available for general release to
customers.  The  Company generally recognizes amortization expense for capitalized software costs using the straight-line method.  Internally developed software products are
reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable and its carrying amount exceeds its fair
value.

Convertible Instruments

The  Company accounts for convertible instruments (when it has determined that the embedded conversion options should not be bifurcated from their host instruments) in
accordance with ASC 470-20, Debt with Conversion and Other Options. Accordingly, the Company records, when necessary, discounts to convertible notes for the intrinsic value
of conversion options embedded in debt instruments based upon the differences between the fair value of the underlying common stock at the commitment date of the note
transaction and the effective conversion price embedded in the note. Debt discounts under these arrangements are amortized over the term of the related debt to their earliest date
of redemption.

Fair Value of Financial Instruments

The  valuation  techniques  utilized  are  based  upon  observable  and  unobservable  inputs.  Observable  inputs  reflect  market  data  obtained  from  independent  sources,  while
unobservable inputs reflect internal market assumptions. These two types of inputs create the following fair value hierarchy:

Level 1 — Quoted prices in active markets for identical assets or liabilities.

F-11

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE B – SUMMARY OF ACCOUNTING POLICIES, continued

Level 2 — Observable inputs other than Level 1 prices such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active or other inputs

that are observable or can be corroborated by observable market data for substantially the full term of the related asset or liabilities.

Level 3 — Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of assets or liabilities.

The Company utilizes observable market inputs (quoted market prices) when measuring fair value whenever possible.

For fair value measurements categorized within Level 3 of the fair value hierarchy, the Company’s accounting and finance department, who report to the Chief Financial Officer,
determine its valuation policies and procedures. The development and determination of the unobservable inputs for Level 3 fair value measurements and fair value calculations are
the responsibility of the Company’s accounting and finance department and are approved by the Chief Financial Officer.

Recently Issued Accounting Principles

In November 2018, the Financial Accounting Standards Board (“FASB”) issued ASU 2018-18, “Collaborative Arrangements (Topic 808): Clarifying the Interaction between Topic
808 and Topic 606” (“ASU 2018-18”). The amendments in this update is to clarify certain transactions between collaborative arrangement participants which should be accounted
for as revenue under Topic 606. ASU 2018-18 is effective for public business entities for fiscal years, and interim periods within those fiscal years, beginning after December 15,
2019. Early adoption is permitted. The Company is currently assessing the impact of ASU 2018-18 on its consolidated financial statements.

In June 2018, the FASB issued ASU 2018-07, Compensation – “Stock Compensation (Topic 718): Improvements to Nonemployee Share-based Payment Accounting”, addresses
aspects of the accounting for nonemployee share-based payment transactions. This pronouncement is effective for annual reporting periods and interim periods within those
annual periods beginning after  December 15, 2019.  Early adoption is permitted.  The  Company does not expect the adoption of ASU 2018-18 to have a material impact on its
consolidated financial statements and related disclosures.

In July 2017, the FASB issued a two-part Accounting Standards Update (“ASU”) No. 2017-11, I. Accounting for Certain Financial Instruments With Down Round Features and II.
Replacement  of  the  Indefinite  Deferral  for  Mandatorily  Redeemable  Financial  Instruments  of  Certain  Nonpublic  Entities  and  Certain  Mandatorily  Redeemable  Noncontrolling
Interests With a Scope Exception (“ASU 2017-11”). ASU 2017-11 amends guidance in FASB ASC 260, Earnings Per Share, FASB ASC 480, Distinguishing Liabilities from Equity,
and  FASB ASC 815,  Derivatives and  Hedging.  The amendments in  Part  I of ASU 2018-11 change the classification analysis of certain equity-linked financial instruments (or
embedded features) with down round features. The amendments in Part II of ASU 2017-11 re-characterize the indefinite deferral of certain provisions of Topic 480 that now are
presented as pending content in the Codification, to a scope exception. Those amendments do not have an accounting effect. ASU 20178-11 is effective for public business entities
for fiscal years, and interim periods within those fiscal years, beginning after December 15, 2018. Early adoption is permitted. The Company is currently evaluating the impact of
adopting this guidance.

In May 2017, the FASB issued ASU 2017-09, Compensation – “Stock  Compensation (Topic 718):  Scope of  Modification Accounting” , which provides guidance about which
changes to the terms or conditions of a share-based payment award require an entity to apply modification accounting in Topic 718. This pronouncement is effective for annual
reporting periods and interim periods within those annual periods beginning after December 15, 2017. Early adoption is permitted. The Company does not expect the adoption of
ASU 2017-09 to have a material impact on its consolidated financial statements and related disclosures.

In January 2017, the FASB ASU 2017-01, “Business Combinations (Topic 805): Clarifying the Definition of a Business” (“ASU 2017-01”). The amendments in this update are to
clarify the definition of a business with the objective of adding guidance to assist entities with evaluating whether transactions should be accounted for as acquisitions (or
disposals) of assets or businesses. The definition of a business affects many areas of accounting including acquisitions, disposals, goodwill, and consolidation. The guidance is
effective for annual periods beginning after December 15, 2017, including interim periods within those periods. The Company does not expect the adoption of ASU 2017-01 to have
a material impact on its consolidated financial statements and related disclosures.

In January 2017, the FASB issued ASU No. 2017-04, “Intangibles – Goodwill and Other (Topic 350): Simplifying the Test for Goodwill Impairment” (“ASU 2017-04”). The purpose of
the  amendment  is  to  simplify  how  an  entity  is  required  to  test  goodwill  for  impairment  by  eliminating  Step  2  from  the  goodwill  impairment  test.  Step  2  measures  a  goodwill
impairment loss by comparing the implied fair value of a reporting unit’s goodwill with the carrying amount of that goodwill. For public entities, the amendments in ASU 2017-04 are
effective for interim and annual reporting periods beginning after December 15, 2019. The Company is currently assessing the impact of ASU 2017-04 on its consolidated financial
statements.

In  February  2016,  the  FASB  issued ASU  2016-02,  "Leases  (Topic  842)."  The  objective  of  this  update  is  to  increase  transparency  and  comparability  among  organizations  by
recognizing lease assets and lease liabilities on the balance sheet and disclosing key information about leasing arrangements. This ASU is effective for fiscal years beginning after
December 15, 2018, including interim periods within those annual periods and is to be applied utilizing a modified retrospective approach. The Company is currently evaluating the
new guidance to determine the impact it may have on its consolidated financial statements.

F-12

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE B – SUMMARY OF ACCOUNTING POLICIES, continued

In May 2014, the FASB issued ASU No. 2014-09, “Revenue from Contracts with Customers” (“ASU 2014-09”), which was subsequently modified in August 2015 by ASU No. 2015-
14,  Revenue from  Contracts with  Customers:  Deferral of the  Effective  Date.  This guidance will be effective for fiscal years (and interim reporting periods within those years)
beginning after December 15, 2017, which for the Company is the first quarter of fiscal 2019. The core principle of ASU No. 2014-09 is that companies should recognize revenue
when the transfer of promised goods or services to customers occurs in an amount that reflects what the company expects to receive. It requires additional disclosures to describe
the  nature,  amount,  timing  and  uncertainty  of  revenue  and  cash  flows  from  contracts  with  customers.  In  2016  and  2017,  the  FASB  issued  additional ASUs  that  clarify  the
implementation guidance on principal versus agent considerations (ASU 2016-08), on identifying performance obligations and licensing (ASU 2016-10), and on narrow-scope
improvements  and  practical  expedients  (ASU  2016-12),  revenue  recognition  criteria  and  other  technical  corrections  (ASU  2016-20)  as  well  as  clarifying  the  scope  of  asset
derecognition guidance and accounting for partial sales of nonfinancial assets (ASU 2017-05). The Company performed an evaluation of the impact, including a review of current
accounting policies and practices, as well as customer contracts, to identify differences upon the adoption of the new standard.  Based on the evaluation, the  Company has
identified certain customer contracts, which will require different recognition under the new guidance. The Company had determined that the revenue under certain of its research
and development contracts should be recognized on an overtime basis as compared to ratably over the contract term. Also, the shipment to the Company’s cotton customer during
fiscal  2018  that  included  extended  payment  terms  and  is  included  in  deferred  revenue  as  of  September  30,  2018,  would  have  met  the  criteria  under  the  new  guidance  to  be
recognized as revenue upon shipment. The Company has determined that the guidance will be adopted using the modified retrospective basis with a cumulative adjustment to
opening retained earnings in fiscal 2019; the cumulative adjustment is expected to be approximately $500,000.

F-13

 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE C – INVENTORIES

Inventories consist of the following at September 30, 2018 and 2017:

Raw materials
Finished goods
Total

NOTE D – INTANGIBLE ASSETS

Intangible assets at September 30, 2018 and 2017 are as follows:

Internally developed software (5-year useful life)
Customer relationships (10-year useful life)
Intellectual property (5-15 years)

Less:
Accumulated amortization
Intangible assets, net

2018

2017

147,984    $
73,385     
221,369    $

193,069 
133,399 
326,468 

  $

  $

2018

2017

157,221    $
621,000     
917,350     
1,695,571     

831,368     
864,203    $

157,221 
621,000 
917,350 
1,695,571 

653,495 
1,042,076 

  $

  $

Total amortization expense charged to operations for the fiscal years ended September 30, 2018 and 2017 were $177,872 and $483,823, respectively. Impairment expense of $253,977
relating to internally developed software was included in amortization expense included in depreciation and amortization within the consolidated statements of operations for the
fiscal year ended September 30, 2017.

F-14

 
 
 
 
 
 
 
   
 
   
 
 
 
 
 
   
 
   
   
 
   
   
      
  
   
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE E – INTANGIBLE ASSETS

The following table presents the estimated amortization expense of the intangible assets for each of the five succeeding years as of September 30, 2018:

2019

2020

2021

2022

2023

Thereafter

Total

NOTE F – ACCOUNTS PAYABLE AND ACCRUED LIABILITIES

Accounts payable and accrued liabilities at September 30, 2018 and 2017 are as follows:

Accounts payable
Accrued salaries payable
Other accrued expenses
Total

NOTE G – SECURED CONVERTIBLE NOTES PAYABLE

  Amount  

 $ 129,435 

   129,435 

   91,967 

   91,967 

   91,967 

   329,432 

 $ 864,203 

2018

2017

500,849    $
401,130     
63,188     
965,167    $

382,984 
446,012 
115,137 
944,133 

  $

  $

On August 31, 2018, the Company entered into a securities purchase agreement (the “Purchase Agreement”) with accredited investors and certain members of its management team
and  Board of  Directors (the “Purchaser”), pursuant to which the  Company issued and sold an aggregate of $1,650,000 in principal amount of secured convertible notes (the
“August 31st Notes”) bearing interest at a rate of 6% per annum. As part of the August 31st Notes, the Company’s management and members of the Board of Directors including
the Chairman, President and Chief Executive Officer, purchased August 31st Notes with a principal amount of $1,185,000.

The August 31st Notes are convertible, in whole or in part, at any time, at the option of the Purchasers, into shares of the Company’s Common Stock, in an amount determined by
dividing the principal amount of each August 31st Note, together with any and all accrued and unpaid interest, by the conversion price of $2.50. The Company has the right to
require the Purchasers to convert all or any part of their August 31st Notes into shares of its Common Stock at a conversion price of $2.50 if the price of the Common Stock remains
at a closing price of $3.50 or more for a period of twenty consecutive trading days.

Upon any Change in Control (as defined in the August 31st Notes), the Purchasers have the right to require the Company to redeem the August 31st Notes, in whole or in part, at a
redemption price equal to such August 31st Notes’ outstanding principal balance plus accrued interest.

The August 31st Notes contain certain events of default that are customarily included in financing of this nature. If an event of default occurs, the Purchasers may require the
Company to redeem the August 31st Notes, in whole or in part, at a redemption price equal to such notes’ outstanding principal balance plus accrued interest.

The August 31st Notes bear interest at the rate of 6% per annum, payable semi-annually in cash or in kind, at the Company’s option, and are due and payable in full on August 30,
2021.  Until the principal and accrued but unpaid interest under the August 31st  Notes is paid in full, or converted into shares of common stock pursuant to their terms, the
Company’s obligations under the August 31st Notes will be secured by a lien on substantially all assets of the Company (excluding certain cash accounts) and the assets of APDN
(B.V.I.) Inc.

F-15

 
 
 
 
 
 
 
 
  
 
  
  
 
  
  
 
  
  
 
  
  
 
  
  
 
  
  
 
 
 
 
 
   
 
   
   
 
 
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE G – SECURED CONVERTIBLE NOTES PAYABLE, continued

The Company has also entered into a registration rights agreement, dated as of the date of the Purchase Agreement (the “Registration Rights Agreement”), with the Purchasers,
pursuant to which it has agreed to prepare and file a registration statement with the SEC to register under the Securities Act of 1933, as amended (the “Securities Act”) resales from
time to time of the Common Stock issued or issuable upon conversion or redemption of the Notes. The Company is required to file a registration statement within 60 days of
receiving a demand registration request from holders of a majority of the outstanding principal balance of the Notes, and to cause the registration statement to be declared effective
within 45 days (or 90 days if the registration statement is reviewed by the SEC).

The Company recorded $64,848 to debt issuance costs based on the cost incurred to complete the financing.  During the fiscal year ended  September 30, 2018, the  Company
amortized $1,479 of debt issuance costs resulting in unamortized debt issuance costs of $63,369 and carrying value of $1,586,631 at September 30, 2018. The debt issuance cost will
be amortized over the life of the Notes. During the fiscal year ended September 30, 2018, the Company incurred approximately $8,136 of interest expense and for the fiscal year
ended September 30, 2018. The effective interest for the fiscal year ended September 30, 2018 was 7.4%.

On November 29, 2018, the Company closed a securities purchase agreement with its chairman, president and chief executive officer and one member of the management team,
pursuant  to  which  the  Company  issued  and  sold  an  aggregate  of  $550,000  in  principal  amount  of  secured  convertible  notes  bearing  interest  at  a  rate  of  6%  per  annum  (the
“November 29th Notes”). The November 29th Notes are substantially similar to the Company’s August 31 Notes except with respect to maturity date. The November 29th Notes are
secured on a pari passu basis with the same Company assets as the August 31 Notes.

NOTE H – CAPITAL STOCK

Common Stock Transactions during the Fiscal Year Ended September 30, 2018:

On December 22, 2017, the Company entered into a securities purchase agreement with certain institutional investors for the purchase and sale of 2,735,000 shares of our common
stock and warrants to purchase an aggregate of 2,735,000 shares of common stock in a registered direct offering with an aggregate gross proceeds of $4,786,250, at a combined
purchase price of $1.75 per share. The warrants will be immediately exercisable at a price of $2.00 per share of common stock and will expire five years from the date of issuance.

After deducting placement agent fees and other estimated expenses related to the registered direct offering, the aggregate net proceeds were approximately $4,200,000.

The warrants will be exercisable for five years from the grant date, but not thereafter. The warrants include an adjustment provision that, subject to certain exceptions, reduces their
exercise price if the Company issues Common Stock or Common Stock equivalents at a price lower than the then-current exercise price of the Purchase Warrants, subject to a
minimum exercise price of $0.44. The exercise price and number of the shares of our Common Stock issuable upon the exercise of the warrants will be subject to adjustment as set
forth therein (including for stock dividends and splits, reverse stock split, recapitalization, reorganization or similar transaction).

In addition, if and only if there is no effective registration statement registering, or no current prospectus available for, the resale of the Purchase Warrants, the Purchasers may
exercise the Purchase Warrants by means of a “cashless exercise.”

F-16

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE H – CAPITAL STOCK, continued

Common Stock Transactions during the Fiscal Year Ended September 30, 2017:

On November 2, 2016, the Company entered into a securities purchase agreement with an institutional investor providing for the purchase of $5 million of common stock and
warrants at a combined price of $2.20 per share of common stock and warrant (the “Private Placement”). In the Private Placement, the Company sold 2,272,727 shares of its common
stock and warrants to purchase 2,272,727 shares of its common stock. The warrants have the same terms as the Company’s existing publicly traded warrants (APDNW) with an
exercise price of $3.50 per share and an expiration date of November 20, 2019. The offering closed on November 7, 2016.

The Company filed a registration statement providing for the resale of these securities on Form S-3 by December 7, 2016. Upon effectiveness of the registration statement, it is
expected that the common stock and warrants issued in the Private Placement will be freely tradeable on The NASDAQ Capital Market under the symbols “APDN” and “APDNW”,
respectively.

The aggregate gross proceeds to the Company from the Private Placement were $5 million before deducting the placement agents’ fee and other offering expenses.

In connection with the closing of this Private Placement, as partial compensation, on November 7, 2016, the Company granted warrants to purchase an aggregate of 68,182 shares
of its common stock to the Company’s placement agents, Maxim Group LLC and Imperial Capital LLC (the “Placement Agent Warrants”) at an exercise price of $2.53 (115% of the
public offering price), subject to adjustment as set forth therein (including for stock dividends and splits and certain other distributions and “Fundamental  Transactions,” as
defined therein). The Placement Agent Warrants will be exercisable beginning six months following the closing date of the Private Placement and terminate at 5:00 P.M. (Eastern
Standard Time) on November 7, 2021. In addition, the Placement Agent Warrants provide for cashless exercise, which the Placement Agents may elect if there is no effective
registration statement registering the resale of the shares issuable upon exercise of the Placement Agent Warrants. The number of shares of common stock that may be acquired by
the Placement Agents upon any exercise of the Placement Agent Warrants (or otherwise in respect hereof) shall be limited to the extent necessary to insure that, following such
exercise,  the  total  number  of  shares  of  common  stock  then  beneficially  owned  by  the  Placement Agent  and  its Affiliates  (as  defined  therein)  and  any  other  Persons  whose
beneficial ownership of common stock would be aggregated with the Placement Agent pursuant to the Exchange Act, does not exceed 9.99% of the total number of issued and
outstanding shares of common stock.

On June 28, 2017 the Company entered into subscription agreements for a private placement of its common stock, with a group of investors, including a strategic investor which is
also a key customer and intellectual property licensee of the Company as well as all of the Company’s executive officers and all members of the Board of Directors (the “June
Private Placement”). As a result of the June Private Placement, the Company issued 1,025,574 shares of common stock at a price of $1.76 per share for total gross proceeds of
$1,805,000. As  part  of  the  June  Private  Placement,  the  Company’s  management  and  Board  of  Directors  purchased  315,346  shares  of  common  stock  for  gross  proceeds  of
$555,000. The issuance of the Common Stock was exempt from the registration requirements of the Securities Act of 1933 pursuant to Section 4(a)(2) of such Securities Act and
Regulation  D promulgated thereunder and such  Common  Stock therefore is restricted.  Each investor gave representations that he, she or it was an “accredited investor” (as
defined under Rule 501 of Regulation D) and that he, she or it is purchasing such securities without a present view toward a distribution of the securities. In addition, there was no
general solicitation conducted in connection with the offer and sale of the securities.

NOTE I – STOCK OPTIONS AND WARRANTS

Warrants

Transactions involving warrants (see Note H) are summarized as follows:

Balance at October 1, 2017
Granted
Exercised
Cancelled or expired
Balance, September 30, 2018

F-17

Number of 
Shares

Weighted Average 
Exercise Price Per
Share

9,540,455    $
2,735,000     
(-)     
(66,928)    
12,208,527    $

3.60 
2.00 
(- ) 
(2.88)
3.24 

 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
   
 
   
   
   
   
   
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE I – STOCK OPTIONS AND WARRANTS, continued

Stock Options

In 2005, the Board of Directors and the holders of a majority of the outstanding shares of common stock approved the Incentive Plan. In 2007, 2008, 2012 and 2015, the Board of
Directors and holders of a majority of the outstanding shares of common stock approved various increases in the number of shares of common stock that can be issued as stock
awards and stock options thereunder to an aggregate of 8,333,333 shares and the number of shares of common stock that can be covered by awards made to any participant in any
calendar year to 833,334 shares. The Incentive Plan’s expiration date is January 25, 2025.

The Incentive Plan is designed to retain directors, executives, and selected employees and consultants by rewarding them for making contributions to our success with an award of
options to purchase shares of common stock. As of September 30, 2018, a total of 275,752 shares have been issued and options to purchase 6,704,115 shares have been granted
under the Incentive Plan.

F-18

 
 
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE I – STOCK OPTIONS AND WARRANTS, continued

Stock Options, continued

Transactions involving stock options issued are summarized as follows:

Outstanding at October 1, 2017
Granted
Exercised
Cancelled or expired
Outstanding at September 30, 2018
Vested at September 30, 2018
Non-vested at September 30, 2018

Number of
Shares

Weighted Average
Exercise Price Per
Share

Aggregate
Intrinsic
Value

Weighted
Average
Contractual
Life (years)

5,333,227    $
2,188,141     
-     
(1,338,154)    
6,183,214    $
5,392,896     
790,318     

3.71     
2.00     
-     
3.58     
3.13     
3.31    $
     $

273,951     
10,542     

5.81 
8.92 

For  the  fiscal  year  ended  September  30,  2018,  the  Company  issued  an  aggregate  of  2,188,141  (including  award  modifications  of  666,667)  options  to  employees,  consultants,
members of the strategic advisory board and non-employee board of director members. Included in these grants was 500,000 options granted to executives.

For the fiscal year ended September 30, 2017, the Company issued 1,099,844 (including award modifications of 119,182 options) options to employees, consultants, members of the
strategic advisory board and non-employee board of director members. Included in these grants was 280,000 options granted to executives and 5,000 performance based options
issued to a consultant. These performance based options vest when a certain performance condition is met by the consultant.

The fair value of options granted during the fiscal years ended September 30, 2018 and 2017 was determined using the Black Scholes Option Pricing Model. For the purposes of the
valuation model, the Company used the simplified method for determining the granted options expected lives. The simplified method is used since the Company does not have
adequate historical data to utilize in calculating the expected term of options. The fair value for options granted was calculated using the following weighted average assumptions:

Stock price
Exercise price
Expected term
Dividend yield
Volatility
Risk free rate

  $
  $

2018

2017

  $
  $

1.31 
2.00 
4.42 
- 
86%   
2.70%   

2.11 
2.31 
5.38 
- 
111%
2.0%

The Company recorded $1,356,351 and $3,257,305 as stock compensation expense within selling, general and administrative for fiscal years ended September 30, 2018 and 2017,
respectively. Included in this amount is $145,053 and $89,951 for the fiscal years ended September 30, 2018 and 2017, respectively for employee stock option modifications. These
modifications extended the term of the option for an employee in fiscal 2018 and extended the terms of the options for a former employee in fiscal 2017. As of September 30, 2018,
unrecorded compensation cost related to non-vested awards was $619,060, which is expected to be recognized over a weighted average period of approximately 0.81 years. The
weighted average grant date fair value per share for options granted during the fiscal years ended September 30, 2018 and 2017 was $0.75 and $1.58, respectively.

F-19

 
 
 
 
 
 
 
 
   
   
   
 
   
      
  
   
      
  
   
      
  
   
      
  
   
      
  
   
   
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE J – INCOME TAXES

The income tax provision (benefit) for the fiscal years ended September 30, 2018 and 2017 consists of the following:

Federal:
Current
Deferred

State and local:
Current
Deferred

Change in valuation allowance

Income tax provision (benefit)

2018

2017

  $

-     
4,430,000     
4,430,000     

- 
(4,303,000)
(4,303,000)

-     
(925,000)    
(925,000)    

- 
(376,000)
(376,000)  

(3,505,000)    

4,679,000 

  $

-     

- 

The provision for income taxes differs from the amount of income tax determined by applying the applicable U.S. statutory rate to losses before income tax expense for the years
ended September 30, 2018 and 2017 as follows:

Statutory federal income tax rate
Statutory state and local income tax rate (1%, as of September 30, 2018 and 2017), net of federal benefit
Stock based compensation
Other permanent differences
Impact of change in Federal statutory tax rate
Change in valuation allowance
Effective tax rate

2018

2017

24.28%    
2.50%    
(2.29%)   
4.24%    
(58.71%)   
29.98%    
0.00%    

34.00%
1.62%
(2.65%)
3.42%
-%
(36.39%)
0.00%

Deferred income taxes result from temporary differences in the recognition of income and expenses for financial reporting purposes and for tax purposes. The tax effect of these
temporary differences representing deferred tax asset and liabilities result principally from the following:

Deferred tax assets (liabilities):
Stock based compensation
Depreciation and amortization
Net operating loss carry forward
Tax credits
Other
Less: valuation allowance
Net deferred tax asset

September 30,

2018

2017

  $

  $

1,947,000    $
339,000     
13,248,000     
944,000     
69,000     
(16,547,000)    
-    $

2,836,000 
500,000 
16,143,000 
521,000 
52,000 
(20,052,000)
- 

F-20

 
 
 
 
 
 
 
   
 
   
      
  
   
 
   
   
      
  
   
   
 
   
 
   
      
  
   
 
   
      
  
 
 
 
 
 
 
 
 
 
  
 
  
   
   
   
   
   
   
   
 
 
 
 
 
 
 
   
 
   
      
  
   
   
   
   
   
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE J– INCOME TAXES, continued

As of September 30, 2018, the Company has approximately $53,619,000 of Federal and $73,236,000 of State net operating loss “NOL” carryforwards available which begin to expire
after 2022. Pursuant to Internal Revenue Code Section 382, the Company’s ability to utilize the NOLs is subject to certain limitations due to changes in stock ownership in prior
years. The annual limitation ranges between $786,000 and $1,103,000 and any unused amounts can be carried forward to subsequent years.

The Company has provided a full valuation allowance against all of the net deferred tax assets based on management’s determination that it is more likely than not that the net
deferred tax assets will not be realized in the future. The valuation allowance decreased by $3,505,000.

Additionally, deferred tax asset at September 30, 2017 has been revised as follows: deferred tax asset related to amortization of debt discounts is decreased by $16,311,000; the
valuation allowance decreased by $16,311,000, completely offsetting the increase in the deferred tax assets. The revision resulted in no change to the net tax provision of the
Company as of September 30, 2017 and for the fiscal year ended.

The Company has Federal research and development credits of approximately $597,000 that will begin to expire after 2034. The Company also has state investment tax credits of
$340,000 that will begin to expire after 2029.

NOTE K – COMMITMENTS AND CONTINGENCIES

Operating leases
The Company leases office space under an operating lease in Stony Brook, New York for its corporate headquarters. The lease is for a 30,000 square foot building. The term of the
lease commenced on June 15, 2013 and expired on May 31, 2017, with the option to extend the lease for two additional three-year periods. The Company has exercised its option to
extend the lease for one additional three-year period ending May 31, 2018. The base rent during the additional three-year period is $458,098 per annum. In addition to the office
space, the Company also has 1,500 square feet of laboratory space. The term of the lease commenced on November 1, 2015 and expired on October 31, 2018, with a month to month
agreement thereafter. Effective November 20, 2018, the Company renewed this lease for one additional year, ending October 31, 2018. The Company set up a satellite testing facility
in Ahmedabad, India during fiscal 2018. On November 17, 2017, it leased 1,108 square feet for a three-year term beginning November 1, 2017. The base rent is approximately $6,500
per annum.

Total rent expense for the fiscal years ended September 30, 2018 and 2017 were $528,234 and $552,240, respectively.

Future minimum rental payments (excluding real estate tax and maintenance costs) as of September 30, 2018 are as follows:

For the fiscal year ending September 30,

2019
2020
2021
Total

Employment and Consulting Agreements

Employment agreements

  $

  $

316,457 
7,104 
595 
324,156 

On July 11, 2011, the Company’s Board of Directors approved the terms of employment for Dr. James A. Hayward, the Company’s Chief Executive Officer (“CEO”).

The  CEO’s  employment  agreement  provides  that  he  will  be  the  Company’s  CEO,  and  will  continue  to  serve  on  the  Company’s  Board  of  Directors.  On  July  28,  2017,  a  new
employment agreement was entered into with the CEO effective July 1, 2017. The initial term was from July 1, 2017 through June 30, 2018, with automatic one-year renewal periods.
As of June 30, 2018, the employment contract renewed for an additional year. Under the new agreement, the CEO will be eligible for a special cash incentive bonus of up to
$800,000, $300,000 of which is payable if and when annual revenue reaches $8 million and $100,000 of which would be payable for each $2 million of annual revenue in excess of $8
million. Pursuant to the contract, the CEO’s annual salary is $400,000. The Board of Directors, acting in its discretion, may grant annual bonuses to the CEO. The CEO will be
entitled to certain benefits and perquisites and will be eligible to participate in retirement, welfare and incentive plans available to the Company’s other employees.

F-21

 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
 
 
APPLIED DNA SCIENCES, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
SEPTEMBER 30, 2018 and 2017

NOTE K – COMMITMENTS AND CONTINGENCIES, continued

The agreement with the CEO also provides that if he is terminated before the end of the initial or a renewal term by the Company without cause or if the CEO terminates his
employment  for  good  reason,  then,  in  addition  to  previously  earned  and  unpaid  salary,  bonus  and  benefits,  and  subject  to  the  delivery  of  a  general  release  and  continuing
compliance with restrictive covenants, the CEO will be entitled to receive a pro rata portion of the greater of either (X) the annual bonus he would have received if employment had
continued through the end of the year of termination or (Y) the prior year’s bonus; salary continuation payments for two years following termination equal to the greater of (i) three
times base salary or (ii) two times base salary plus bonus; company-paid COBRA continuation coverage for 18 months post-termination; continuing life insurance benefits (if any)
for two years; and extended exercisability of outstanding vested options (for three years from termination date or, if earlier, the expiration of the fixed option term). If termination of
employment as described above occurs within six months before or two years after a change in control of the Company, then, in addition to the above payments and benefits, all of
the CEO’s outstanding options and other equity incentive awards will become fully vested and the CEO will receive a lump sum payment of the amounts that would otherwise be
paid as salary continuation. In general, a change in control will include a 30% or more change in ownership of the Company.

Upon termination due to death or disability, the CEO will generally be entitled to receive the same payments and benefits he would have received if his employment had been
terminated by the Company without cause (as described in the preceding paragraph), other than salary continuation payments.

Effective May 7, 2016, the CEO’s annual salary was voluntarily reduced by $100,000. Effective May 20, 2017, the CEO’s annual salary was voluntarily reduced by an additional
$50,000. Accordingly, his current annual base salary as of September 30, 2018 is $250,000.

Effective March 15, 2018, the Compensation Committee of the Company’s Board of Directors, approved a bonus of $118,750 that would be payable to the CEO when the Company
reaches $3,000,000 in revenues for two consecutive quarters or $12,000,000 in revenues for a fiscal year, provided that the CEO is still employed by the Company on such date (the
“Revenue  Bonus”).  Effective  May 2, 2018, the  Compensation  Committee of the  Company’s  Board of  Directors, increased the amount of the  Revenue  Bonus to $395,708.  The
accrual for the Revenue Bonus of $360,125 is recorded to long term accrued liabilities on the balance sheet as of September 30, 2018.

Litigation

From time to time, the Company may become involved in various lawsuits and legal proceedings which arise in the ordinary course of business. When the Company is aware of a
claim or potential claim, it assesses the likelihood of any loss or exposure. If it is probable that a loss will result and the amount of the loss can be reasonably estimated, the
Company will record a liability for the loss. In addition to the estimated loss, the recorded liability includes probable and estimable legal costs associated with the claim or potential
claim. Litigation is subject to inherent uncertainties, and an adverse result in these or other matters may arise from time to time that may harm the Company’s business. There is no
pending litigation involving the Company at this time.

NOTE L – GEOGRAPHIC AREA INFORMATION

Net revenues by geographic location of customers are as follows: 

Americas
Europe
Asia and other
Total

F-22

Year Ended September 30,
2017
2018

2,141,169    $
1,004,452     
757,722     
3,903,343    $

3,485,691 
1,055,125 
210,444 
4,751,260 

  $

  $

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
   
   
 
 
 
COLLATERAL AGENCY AGREEMENT

Exhibit 10.39

THIS  COLLATERAL AGENCY AGREEMENT  (this  “ Agreement”)  is  made  effective  as  of  October  19,  2018,  between  DELAWARE  TRUST  COMPANY,  a  Delaware
corporation (the “Collateral Agent”), APPLIED DNA SCIENCES, INC., a Delaware corporation (the “Issuer”), APDN (B.V.I.) INC., a corporation organized under the laws of the
British  Virgin  Islands  (“APDN  (B.V.I.”),  collectively  with  the  Issuer,  the  “Debtors”),  and  each  of  the  investors  listed  on Schedule  1  attached  hereto  (each  a  “Buyer”  and
collectively, the “Buyers”).

WITNESSETH:

WHEREAS, the Borrower and the Buyers are parties to that certain Securities Purchase Agreement dated as of August 31, 2018 (the “ Securities Purchase Agreement”)
and certain other agreements, documents and instruments executed and delivered in connection therewith (together with the Securities Purchase Agreement and this Agreement,
collectively, the “Transaction Documents”), pursuant to which the Grantor shall be required to sell, and the Buyers shall purchase or have rights to purchase, on a several and not
joint basis, the principal amount of the Notes issued pursuant thereto (as such Notes may be amended, amended and restated, supplemented or otherwise modified from time to
time, the “Notes”).

WHEREAS, the obligations of the Debtors under the Transaction Documents, including all fees, commissions, expense reimbursements, indemnifications and all other
amounts due or to become due under this Agreement, are secured by all of the Debtors’ existing and future personal property (the “ Collateral”) as more fully described in (i) the
Security Agreement and the  Guaranty and  Security Agreement, each dated as of the date hereof by each  Debtor in favor of the  Collateral Agent (collectively, the “ Security
Agreements”; capitalized terms used but not otherwise defined herein shall have the meanings assigned thereto in the Security Agreements) and (ii) the Intellectual Property
Security Agreement(s) by Debtors in favor of the Collateral Agent (collectively with the Security Agreements, the “Collateral Documents”).

WHEREAS, for the orderly administration of the Collateral, the Buyers desire to utilize and appoint the Collateral Agent, and the Collateral Agent has agreed to accept
such appointment, as the Buyers’ representative and agent under the Collateral Documents to take certain actions from time to time in connection with the Collateral, all upon the
terms and subject to the conditions set forth herein.

 
 
 
 
 
 
 
 
 
 
NOW, THEREFORE, in consideration of the premises set forth herein and for other good and valuable consideration, the parties hereto agree as follows:

Section 1. Appointment of Collateral Agent; Financing Statements.

(a)       Notwithstanding anything to the contrary in the other Transaction Documents to the contrary, including but not limited to Section 4(d) of the Securities Purchase
Agreement,  on  the  terms  and  subject  to  the  conditions  set  forth  herein,  each  Buyer  hereby  appoints  the  Collateral Agent,  and  the  Collateral Agent  hereby  accepts  such
appointment, to (i) serve as the Secured Parties’ representative and agent for purposes of filing financing statements against each Debtor with respect to the Collateral, including
by listing the Collateral Agent as secured party of record thereon (as such term is used in the UCC), and the Collateral Agent agrees that, in such capacity, the Collateral Agent
shall be the representative of the Secured Parties for purposes of satisfying the requirements of Section 9-502(a)(2) of the UCC, whether or not the Collateral Agent is indicated in
any such financing statement as acting in its capacity as a representative and agent of the Secured Parties (as contemplated under Section 9-503(d) of the UCC), (ii) serve as the
Secured Parties’ representative and agent for purposes of satisfying the requirements of Section 9.104(a)(3) of the UCC, and (iii) take such other action or actions as the Collateral
Agent may be directed in writing from time to time by the Buyers to create, perfect, preserve or maintain the Secured Parties’ security interest in the Collateral or enforce any and all
rights and remedies, in whole or in part, available to the Secured Parties under the Collateral Documents with respect to the Collateral. In furtherance of the foregoing, the Collateral
Agent hereby agrees to promptly take any other action (x) required or directed in writing by the Buyers from time to time in order to maintain the perfection of, and preserve or
protect, the Secured Parties’ security interests in the Collateral, (y) necessary in any bankruptcy or insolvency proceeding with respect to any Debtor to evidence the appointment
of the Collateral Agent hereunder and the perfection, preservation and maintenance of the Collateral in favor of the Secured Parties or (z) permitted or required to be taken by a
secured party of record under the UCC and directed in writing by the Buyers from time to time in order to carry out more effectively the purposes of this Agreement.

(b)       The Collateral Agent further agrees that (i) the Buyers shall, and are hereby authorized to, file all initial financing statements against each Debtor with respect to the
Collateral, which financing statements shall list the  Collateral Agent as secured party of record thereon, and (ii) it will not amend, nor will it consent the amendment of, any
financing statements filed against any Debtor with respect to the Collateral without the prior written consent of the Buyers (not to be unreasonably withheld, conditioned or
delayed).

(c)       The Collateral Agent shall have no liability under, and no duty to inquire as to the provisions of, any agreement other than this Agreement and the Collateral
Documents (provided that in the case of any conflict between this Agreement and the Collateral Documents or any other Transaction Document, the terms of this Agreement shall
control). The Collateral Agent may rely upon, and shall not be liable for acting or refraining from acting upon, any written notice, instruction or request furnished to it hereunder
and reasonably believed by it to be genuine and to have been signed or presented by the proper party or parties except to the extent directly or indirectly caused by the gross
negligence or willful misconduct of the Collateral Agent, as finally adjudicated by a court of competent jurisdiction, or the Collateral Agent’s taking of any action in violation of
this Agreement. The Collateral Agent shall be under no duty to inquire into or investigate the validity, accuracy or content of any such document. The Collateral Agent shall not
be liable for any action taken or omitted by it in good faith except to the extent directly or indirectly caused by the gross negligence or willful misconduct of the Collateral Agent, as
finally adjudicated by a court of competent jurisdiction, or the Collateral Agent’s taking of any action in violation of this Agreement. The Collateral Agent shall have no liability for
assets lost or damaged while being delivered to the Collateral Agent except to the extent directly or indirectly caused by the gross negligence or willful misconduct of the Collateral
Agent, as finally adjudicated by a court of competent jurisdiction, or the Collateral Agent’s taking of any action in violation of this Agreement. The Collateral Agent may execute
any of its powers and perform any of its duties hereunder directly or through agents or attorneys and may consult with counsel, accountants and other skilled persons to be
selected and retained by it. Anything in this Agreement to the contrary notwithstanding, in no event shall the Collateral Agent be liable for special, indirect or consequential loss
or damage of any kind whatsoever (including but not limited to lost profits), even if the Collateral Agent has been advised of the likelihood of such loss or damage and regardless
of the form of action.

 
 
 
 
 
 
 
 
 
(d)       The provisions of this Section 1 and Section 7 below are solely for the benefit of the Buyers and the Collateral Agent, and the Debtors shall not have any rights as
third party beneficiaries or otherwise of any of the provisions hereof. In performing its functions and duties under the this Agreement and the Collateral Documents, the Collateral
Agent shall act solely as an agent of the Secured Parties and does not assume, and shall not be deemed to have assumed, any obligation towards or relationship of agency or trust
with the Debtors. Notwithstanding any other provisions hereof or of any provision of the Collateral Documents, the Collateral Agent shall not have or be deemed to have any
fiduciary relationship with the Buyers, the Debtors or any other person or entity, and no implied covenants, functions, responsibilities, duties, obligations or liabilities shall be read
into this Agreement or the Collateral Documents or otherwise exist against the Collateral Agent. Without limiting the generality of the foregoing sentence, the use of the term
“agent” in this Agreement or the Collateral Documents with reference to the Collateral Agent is not intended to connote any fiduciary or other implied (or express) obligations
arising under agency doctrine of any applicable law.

Section 2. Notice by Collateral Agent of Certain Events; Continuation Statements.

(a)       The Collateral Agent shall not be deemed to have knowledge or notice of the occurrence of any default unless the Collateral Agent has received a copy of a notice

thereof from a Buyer referring to this Agreement and describing such default.

(b)        The  Collateral Agent shall promptly notify the  Buyers in writing whenever the  Collateral Agent receives notice, including any notices received under or in
connection with the UCC, that (i) any security interest (other than the security interests of the Buyers under the Collateral Documents) has been placed, or attempted to be placed,
on  any  Collateral,  including  any  inquiries  in  respect  of  any  financing  statements  listing  the  Collateral Agent  as  secured  party  of  record  thereunder,  or  (ii)  the  attachment  or
perfection  of  Buyers’  security  interest  in  the  Collateral  shall  have  been  challenged.  The  Collateral Agent  shall  also  promptly  notify  the  Buyers  in  writing  that  any  financing
statement filed against any Debtor with respect to the Collateral which lists the Collateral Agent as secured party of record thereon (each, an “Expiring Financing Statement”) shall
be expiring, and such notice shall be provided by the Collateral Agent no earlier than six months and no later than three months prior to each such expiration (each, an “Expiration
Notice”). If the Collateral Agent shall not have received further instruction from the Buyers within 10 business days following the date on which the Collateral Agent sent an
Expiration Notice with respect to an Expiring Financing Statement, the Collateral Agent shall be, and hereby is, authorized to file, in the appropriate filing office, a continuation
statement with respect to such Expiring Financing Statement and shall provide evidence of the same to the Buyers.

 
 
 
 
 
 
 
 
Section 3. Representations and Warranties. Each party hereto hereby represents and warrants to the other parties hereto as of the date hereof that:

(a)       it is duly organized, validly existing and in good standing under the laws of its jurisdiction of organization;

(b)       it has the full power and authority to execute, deliver and perform this Agreement and has taken all necessary action to authorize the execution, delivery and

performance by it of this Agreement;

(c)       the execution, delivery and performance by it of this Agreement does not violate any provision of its corporate governance documents; and

(d)       this Agreement has been duly authorized, executed and delivered by it and constitutes its legal, valid and binding agreement, enforceable in accordance with its
terms, except as enforceability may be limited by bankruptcy, insolvency, reorganization or other similar laws affecting the enforcement of creditors’ rights generally and by general
principles of equity.

Section 4. Term; Termination . This Agreement shall remain in full force and effect until its termination in accordance with this Section 4. The Buyers (by a vote of the
majority of the holders of a majority of the outstanding principal of the Notes) may, in their sole discretion, terminate this Agreement and remove the Collateral Agent from its
appointment hereunder at any time by giving the Collateral Agent and the Debtors at least thirty (30) days’ prior written notice. The Collateral Agent may terminate this Agreement,
and resign from its appointment hereunder, by giving the Buyers at least thirty (30) days’ prior written notice. If the Collateral Agent at any time shall resign, the Buyers shall (by a
vote of the holders of a majority of the outstanding principal of the Notes), within ten (10) days after such notice, appoint a successor Collateral Agent which shall thereupon
become  the  Collateral Agent  hereunder  and  under  the  Security  Document.  If  no  successor  Collateral Agent  shall  have  been  so  appointed,  and  shall  have  accepted  such
appointment, within the above time frame the retiring  Collateral Agent may (but shall not be obligated to) appoint a successor.  Upon the acceptance of any appointment as
Collateral Agent hereunder by a successor Collateral Agent, such successor Collateral Agent shall be entitled to receive from the retiring Collateral Agent such documents of
transfer and assignment as such successor Collateral Agent may reasonably request, and shall thereupon succeed to and become vested with all rights, powers, privileges and
duties of the retiring Collateral Agent. Regardless of whether any such successor has been appointed and accepted such appointment, the resigning Collateral Agent shall be
discharged from its duties and obligations under this Agreement following the expiration of such thirty (30) day notice period. After the effective date of any retiring Collateral
Agent’s resignation hereunder as collateral agent, the provisions of this Agreement shall inure to its benefit as to any actions taken or omitted to be taken by it while it was
Collateral Agent under this Agreement.

Section 5. Fees. The Debtors jointly and severally agree to pay to the Collateral Agent, upon execution of this Agreement and from time to time thereafter, reasonable
compensation for the services to be rendered hereunder, which, unless otherwise agreed in writing, shall be as described on Schedule 2 attached hereto. In addition, all reasonable
and  documented  out-of-pocket  expenses,  fees  and  disbursements  (including  reasonable  and  documented  attorneys’  fees  and  expenses,  court  costs  and  related  expenses)  in
connection with (a) the negotiation and administration of this Agreement and (b) the enforcement or protection of its rights in connection with this Agreement and the Collateral
Documents (including any expenses incurred as a result of any workout, restructuring or negotiations), shall be billed to the Debtors and payable promptly on demand.

 
 
 
 
 
 
 
 
 
 
 
Section  6.  Indemnity.  The  Debtors  jointly  and  severally  agree  to  indemnify,  defend  and  hold  harmless  the  Collateral Agent  and  its  directors,  officers,  agents  and
employees (collectively, the “Indemnified Parties”) from all loss, liability or expense (including attorneys’ fees and expenses, court costs and other expenses) arising out of or in
connection with the Collateral Agent’s execution and performance of this Agreement, including any Indemnified Party’s following of any instructions or other directions from the
Buyers with respect to the appointment of the Collateral Agent under this Agreement, except, in each case, to the extent that such loss, liability or expense is due to the gross
negligence or willful misconduct of any Indemnified Party, as finally adjudicated by a court of competent jurisdiction, or any Indemnified Party’s taking of any action in violation of
this Agreement. The parties hereto acknowledge that the foregoing indemnities shall survive the termination of this Agreement.

Section 7. Concerning the Collateral Agent.

(a)       Each Buyer acknowledges and agrees that (i) the duties, responsibilities and obligations of the Collateral Agent shall be limited to those expressly set forth in this
Agreement and no duties, responsibilities or obligations shall be inferred or implied, (ii) the Collateral Agent shall not be responsible for any of the agreements referred to or
described  herein,  or  for  determining  or  compelling  compliance  therewith,  and  shall  not  otherwise  be  bound  thereby,  except,  in  each  case,  the  Collateral  Documents,  (iii)  the
Collateral Agent shall not be required to expend or risk any of its own funds or otherwise incur any financial or other liability in the performance of any of its duties hereunder, and
(iv) the Collateral Agent shall not be obligated to take any legal or other action hereunder which might in its judgment involve or cause it to incur any expense or additional liability
unless it shall have been furnished with indemnification and security which it deems, in its sole, reasonable and absolute discretion, to be satisfactory. Except as expressly set forth
herein, the Buyers shall have and retain the sole power and authority to exercise any and all powers and rights with respect to the Collateral.

(b)       The Collateral Agent shall be under no duty to afford the assets in the Collateral any greater degree of care than it gives its own similar property. The Collateral
Agent shall not be liable for any damage, loss or injury resulting from any action taken or omitted in the absence of gross negligence or willful misconduct, as finally adjudicated
by a court of competent jurisdiction, or the Collateral Agent’s taking of any action in violation of this Agreement.

(c)       Notwithstanding any other provision of the Agreement, the Collateral Agent shall not be liable (i) for any indirect, incidental, consequential, punitive or special
losses or damages, regardless of the form of action and whether or not any such losses or damages were foreseeable or contemplated, or (ii) for the acts or omissions of any
nominees, correspondents, designees, agents, subagents or sub-custodians.

(d)       All instructions, directions and notices to the Collateral Agent under this Agreement shall be delivered to the Collateral Agent in writing. In the event the Collateral
Agent receives conflicting instructions hereunder or under any of the  Collateral  Documents, the  Collateral Agent shall be fully protected in refraining from acting until such
conflict is resolved to the satisfaction of the Collateral Agent.

 
 
 
 
 
 
 
 
 
 
(e)       Notwithstanding anything else to the contrary herein or in any other agreement (including the Transaction Documents), any reference to any discretionary action
by, consent, designation, specification, requirement or approval of, notice, request or other communication from, or other direction given or action to be undertaken or to be (or not
to be) suffered or omitted by the Collateral Agent or to any election, decision, opinion, acceptance, use of judgment, expression of satisfaction or other exercise of discretion, rights
or remedies to be made (or not to be made) by the Collateral Agent, it is understood that in all cases the Collateral Agent shall be fully justified in failing or refusing to take any
such action if it shall not have received such written instruction, direction, advice or concurrence of the Buyers as it deems appropriate. This provision is intended solely for the
benefit of the Collateral Agent and its successors and assigns and is not intended to and will not entitle the other parties hereto to any defense, claim or counterclaim, or confer
any rights or benefits on any party hereto.

(f)       The Collateral Agent acknowledges that it has, independently and without reliance upon the Buyers, and based on such documents and information as it has
deemed appropriate, made its own credit analysis and decision to enter into to this Agreement and the Collateral Documents. The Collateral Agent also acknowledges that it will,
independently and without reliance upon the Buyers, and based on such documents and information as it shall from time to time deem appropriate, make its own credit analysis and
decision as to whether it will continue to be party to this Agreement and the Collateral Documents.

(g)       Unless otherwise provided in this Agreement, wherever this Agreement or the Collateral Documents requires or provides for the consent, direction, instructions or
waiver of the Collateral Agent or for an act or thing to be done in a manner or to be satisfactory to the Collateral Agent, the Collateral Agent shall act hereunder and thereunder
with the written consent of or under the written instructions or written direction of the Buyers.

(h)       The Collateral Agent may act in reliance upon any writing or instrument or signature which it, in good faith, believes to be genuine, and may assume the validity
and accuracy of any statement or assertion contained in such a writing or instrument and may assume that any person or entity purporting to give any writing, notice, advice or
instruction in connection with the provisions hereof has been duly authorized to do so. The Collateral Agent may consult with counsel and shall be entitled to act, and shall be
fully protected in any action taken in good faith, in accordance with advice given by counsel. The Collateral Agent shall not be liable to the Debtors or the Buyers for any recitals
or  warranties  herein  or  in  the  Collateral  Documents,  nor  for  the  effectiveness,  enforceability,  validity  or  due  execution  of  the  Collateral  Documents  or  any  other  agreement,
document or instrument, nor to make any inquiry respecting the performance by any party of their respective obligations thereunder. Any such inquiry which may be made by the
Collateral Agent shall not obligate it to make any further inquiry or to take any action.

 
 
 
 
 
 
 
 
Section 8. Collateral Proceeds.

(a)       Except as provided by law, the security interests in the Collateral shall be for the ratable benefit of the Secured Parties, shall rank equally in priority, none being
senior or subordinate to any other. No Secured Party shall contest the validity, perfection, priority or enforceability of the lien of any other Secured Party in the Collateral. Each
Buyer, by its acceptance of the benefits hereof, agrees that it shall have no right individually to realize upon any of the Collateral under the Transaction Documents, pursuant to
applicable law or otherwise.

(b)       Any payment or distribution of assets of any Debtor of any kind or character, whether in cash, property or securities, to creditors upon any dissolution or winding-
up or total or partial liquidation or reorganization of any Debtor, whether voluntary or involuntary or in bankruptcy, insolvency, receivership or other proceedings (each such
payment, distribution and/or amount, together with any other amounts or proceeds of Collateral, is hereafter referred to as “Collateral Proceeds”) received by any Secured Party
shall be held in trust for the benefit of all of Secured Parties and shall be immediately delivered to the Collateral Agent in the amount and form received. All Collateral Proceeds shall
be apportioned, paid over or delivered by the Collateral Agent as follows: first, to the Collateral Agent for the payment or reimbursement of any expenses and fees of, or any other
amount  payable  to,  the  Collateral Agent  hereunder  or  under  the  Transaction  Documents,  and next,  among  the  Buyers  on  a  pro  rata  basis  to  each  in  accordance  with  the
outstanding Secured Obligations to each of the Buyers.

Section 9. Miscellaneous.

( a )        Governing Law. This Agreement shall be governed by and construed according to the laws of the State of New York, without regard to principles of conflicts of

laws.

( b )        Severability. In the event that any condition, covenant or other provision contained herein is held by a court of competent jurisdiction to be invalid or void, the
same shall be deemed severable from the remainder of this Agreement and shall in no way affect any other covenant, condition or provision contained herein. If such condition,
covenant or other provision shall be deemed invalid due to its scope or breadth, such shall be deemed valid to the extent of the scope or breadth permitted by law.

(c)        Entire Agreement; No Modification. This Agreement constitutes the entire agreement among the parties pertaining to the subject matter hereof, and supersedes all
prior agreements and understandings pertaining thereto. No modification or amendment of this Agreement shall be effective except by a written instrument signed by all parties
hereto.

(d )        Successors and Assigns . This Agreement shall be binding upon the permitted successors and assigns of the parties hereto. The Collateral Agent shall not have
the right to assign its rights hereunder without the prior written consent of the Buyers, except that any corporation or association into which the Collateral Agent may be merged or
converted, or with which it may be consolidated, shall become the “Collateral Agent” hereunder so long as the Collateral Agent provides advance written notice to the Buyers at
least 10 business days prior to such merger, conversion or consolidation.

 
 
 
 
 
 
 
 
 
 
 
 
( e )       Counterparts; Electronic Signature. This Agreement may be executed in one or more counterparts and by facsimile or other electronic signature, each of which

counterparts when so executed shall be deemed to be an original, and all of which together shall constitute one and the same agreement.

( f )        Jury Trial Waiver. EACH PARTY HERETO, TO THE EXTENT PERMITTED BY LAW, HEREBY WAIVES ANY RIGHT TO HAVE A JURY PARTICIPATE IN
RESOLVING ANY DISPUTE, WHETHER SOUNDING IN CONTRACT, TORT OR OTHERWISE, ARISING OUT OF, IN CONNECTION WITH, RELATED TO, OR INCIDENTAL TO
THIS AGREEMENT OR ANY OTHER INSTRUMENT, DOCUMENT OR AGREEMENT EXECUTED OR DELIVERED IN CONNECTION HEREWITH OR THE TRANSACTIONS
RELATED THERETO.

(g)       Confidentiality. Each party hereto agrees that the existence and contents of this Agreement, all other information and documents provided to the Collateral Agent
in connection herewith, and the existence of the relationship between the Buyers and the Collateral Agent, and any services provided by the Collateral Agent in connection
therewith, are and shall remain confidential and shall not be disclosed to any third party, except for such information (i) as may become generally available to the public by filing of
UCC-1 financing statements or otherwise, (ii) as may be required or appropriate in response to any summons, subpoena, or otherwise in connection with any litigation, arbitration,
administrative or similar proceeding, or to comply with any applicable law, order, regulation, ruling, request from governmental regulators, and provided that, if possible, notice of
such disclosure is provided to the other party prior thereto, (iii) as may be obtained from a non-confidential source that disclosed such information in a manner that did not violate
its obligations to the other party in making such disclosure, or (iv) as may be furnished to that party’s affiliates, or its affiliates’ auditors, attorneys, advisors, lenders and credit
rating agencies which are required to keep the information that is disclosed in confidence. Without limiting the foregoing, upon the Collateral Agent’s receipt of an inquiry from a
third party regarding any financing statements of record against any Debtor with respect to the Collateral listing the Collateral Agent as secured party of record thereon, the
Collateral Agent shall promptly provide notice of the same to the Buyers, and shall only respond to such inquiry in accordance with instructions provided by the Buyers.

(h)       Notices. All notices hereunder shall be in writing and delivered to each party at the address set forth for such party on the signature pages hereto.

( i )        Conflicts. In the case of any conflict between this Agreement and any other Transaction Document, including but not limited to Section 4(d) of the Securities

Purchase Agreement, the terms of this Agreement shall control.

Section 10. Extension and Post-Closing Obligation.

(a)      Extension. The Buyers and the Company hereby agree to extend all delivery dates set forth in the Securities Purchase Agreement for the granting of liens securing
of the Notes and the perfection of the security interests contemplated therein for completion within a period of thirty (30) days from the date hereof, as such period may be
extended by the Collateral Agent, in its reasonable discretion; provided, however, that, all of the Buyers may agree in writing to instruct the Collateral Agent not to perfect its
security interest, for the benefit of the Secured Parties, in certain types of Collateral if, in the reasonable judgment of all the Buyers, the expense or process for achieving such
perfection is determined to be unduly burdensome.

 
 
 
 
 
 
 
 
 
 
 
( b )       Post-closing Obligation. The Issuer hereby agrees to deliver to the Collateral Agent a certificate of good standing issued by the appropriate authority under the
laws of the British Virgin Islands, in substance reasonably satisfactory to the Collateral Agent, by no later than thirty (30) days after the date hereof, as such period may be
extended by the Collateral Agent, in its reasonable discretion.

[Signature page to follow]

 
 
 
 
 
 
IN WITNESS WHEREOF, the parties have executed and delivered this Agreement to be effective as of the date first above stated.

COLLATERAL AGENT:

DELAWARE TRUST COMPANY

By:
Print Name:
Title:

/s/ Alan R. Halpern
Alan R. Halpern
Vice President

Address for notices:

Delaware Trust Company
251 Little Falls Dr.
Wilmington, DE 19808
Attention: Corporate Trust Administration
Fax: 302-636-8666
E-mail: trust@delawaretrust.com

with a copy to:

Miles & Stockbridge, P.C.
1500 K Street, NW, Suite 800
Washington, DC 20005
Attention: Abbey M. Ruby
E-mail: aruby@milesstockbridge.com

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BUYERS:

By:
/s/ James A. Hayward
Print Name:  James A. Hayward

By:   /s/ Judith Murrah
Print Name:  Judith Murrah

By:   /s/ Yavoc Shamash
Print Name:  Yavoc Shamash

By:   /s/ Robert Catell
Print Name:  Robert Catell

By:   /s/ Elizabeth Schmalz Ferguson
Print Name:  Elizabeth Schmalz Ferguson

By:   /s/ Gregg Baldwin
Print Name:  Gregg Baldwin

By:   /s/ William Montgomery
Print Name:  William Montgomery

By:   /s/ Johnette van Eeden
Print Name:  Johnette van Eeden

By:   /s/ John Cartier
Print Name:  John Cartier

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BUYERS (continued)

Delabarta II

By:   /s/ John F. Bitzer III
Print Name:  John F. Bitzer III
Title:  President

The Rodgers Living Trust Dated April 7, 1995

By:   /s/ Jay D. Rodgers
Print Name:  Jay D. Rodgers
Title:  Trustee

Addresses for Notices:

See Schedule 1 attached hereto

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
DEBTORS:

APPLIED DNA SCIENCES, INC.

By:   /s/ Beth Jantzen
Print Name:  Beth Jantzen, CPA
Title:  Chief Financial Officer

APDN (B.V.I.) INC.

By:   /s/ James A. Hayward
Print Name:  James A. Hayward
Title:  Authorized Signatory

Address for notices:

50 Health Sciences Drive
Stony Brook, NY 11790
Attn: Beth Jantzen, CPA
Facsimile: 631-240-8900

with a copy to:

Pepper Hamilton LLP
The New York Times Building
37th Floor
620 Eighth Avenue
New York, NY  10018-1405
Attention: Merrill M. Kraines
E-mail: krainesm@pepperlaw.com

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Buyer

James A. Hayward
Judith Murrah
Delabarta II

Yavoc Shamash
Robert Catell
Elizabeth Schmalz Ferguson
The Rodgers Living Trust Dated April 7, 1995
Gregg Baldwin
William Montgomery
Johnette van Eeden
John Cartier

SCHEDULE 1

SCHEDULE OF BUYERS

Address for Notices

1 Emmet Drive, Stony Brook, NY 11790
8 Old Post Lane, Saint James, NY 11780
c/o Delaware Corporate  Management, 1105 North Market Street, Suite 1300,
Wilmington, DE  19801
7 Quaker Hill Road, Stony Brook, NY 11790
62 Osborne Road, Garden City, NY 11530
101 Jersey Avenue, Spring Lake, NJ 07762
1277 Porter Road, Flower Mound, TX 75022
3391 Ichabod Way, The Villages, FL 32163
34211 Seavey Loop Road, Eugene, OR 97405
451 Westpark Way, Suite 5, Euless, TX 76040
P.O. Box East Hampton, NY 11937

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Initial Set Up Fee: $2,500, payable upon execution of this Agreement (which fee shall be fully earned and non-refundable upon payment)

Annual Fee: $7,500, payable annually in advance on the date of this Agreement and on each anniversary of the date of this Agreement (which fee shall be fully earned and non-
refundable upon payment)

SCHEDULE 2

FEE SCHEDULE

 
 
 
 
 
 
 
 
 
 
Exhibit 10.40

EXECUTION VERSION

SECURITY AGREEMENT

dated October 19, 2018

by

the Grantor referred to herein

as Grantor

to

Delaware Trust Company

as Collateral Agent

 
 
 
 
 
 
 
TABLE OF CONTENTS

PAGE

Section 1.

Section 2.

Section 3.

Section 4.

Section 5.

Section 6.

Section 7.

Section 8.

Section 9.

Grant of Security

Security for Obligations

Grantor Remains Liable

Delivery and Control of Security Collateral.

Maintaining the Account Collateral

Representations and Warranties

Further Assurances.

As to Equipment and Inventory.

As to Books and Records.

Section 10.

Insurance.

Section 11.

Post-Closing Changes; Collections on Assigned Agreements, Receivables and Related Contracts.

Section 12.

As to Intellectual Property Collateral.

Section 13.

Voting Rights; Dividends; Etc.

Section 14.

As to Letter-of-Credit Rights.

Section 15.

Commercial Tort Claims

Section 16.

Transfers and Other Liens; Additional Shares.

Section 17.

Collateral Agent Appointed Attorney in Fact

Section 18.

Collateral Agent May Perform

Section 19.

The Collateral Agent’s Duties.

Section 20.

Remedies

Section 21.

Indemnity and Expenses.

Section 22.

Amendments; Waivers; Additional Grantors; Etc.

Section 23.

Notices, Etc.

2

5

6

6

7

7

10

11

11

12

12

13

13

14

15

15

15

16

16

17

19

19

19

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Section 24.

Continuing Security Interest

Section 25.

Release; Termination.

Section 26.

Execution in Counterparts

Section 27.

Governing Law; Jurisdiction; Waiver of Jury Trial, Etc.

20

20

20

21

Schedules:

Schedule I
Schedule II
Schedule III
Schedule IV
Schedule V
Schedule VI
Schedule VII
Schedule VIII
Schedule IX
Schedule X
Schedule XI

Exhibits:

Exhibit A
Exhibit B

-
-
-
-
-
-
-
-
-
-

-
-

Investment Property
Deposit Accounts
Assigned Agreements
Intellectual Property
Commercial Tort Claims
Location, Chief Executive Office, Type of Organization, Jurisdiction of Organization and Organizational Identification Number
Changes in Name, Location, Etc.
Locations of Equipment, Inventory and Books and Records
Letters of Credit
Permitted Liens
Excluded Assets

Form of Intellectual Property Security Agreement
Form of IP Security Agreement Supplement

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
SECURITY AGREEMENT

SECURITY AGREEMENT (as amended, supplemented, amended and restated or otherwise modified from time to time, this “Agreement”) dated October 19, 2018
made by APPLIED DNA SCIENCES, INC., a Delaware corporation with headquarters located at 50 Health Sciences Drive, Stony Brook, New York 11790 (the “ Grantor”), in favor of
DELAWARE TRUST COMPANY, a Delaware corporation, as collateral agent (together with any successor collateral agent, in such capacity, the “Collateral Agent”) for the benefit
of the investors listed on the Schedule of Buyers (each a “Buyer” and collectively, the “Buyers”; the Buyers and the Collateral Agent are collectively, with their successors and
assigns, the “Secured Parties”)) set forth in the Securities Purchase Agreement, dated as of August 31, 2018 (as amended, amended and restated, supplemented or otherwise
modified from time to time) and the other Secured Parties (the “Securities Purchase Agreement”).

PRELIMINARY STATEMENTS.

WHEREAS, the Grantor and each Buyer are parties to the Securities Purchase Agreement, pursuant to which the Grantor shall be required to sell, and the Buyers
shall purchase or have rights to purchase, on a several and not joint basis the principal amount of the Notes issued pursuant thereto (as such Notes may be amended, amended
and restated, supplemented or otherwise modified from time to time, the “Notes”); and

WHEREAS, it is a condition precedent to the Buyers purchasing the Notes pursuant to the Securities Purchase Agreement that the Grantor shall have executed
and delivered to the Collateral Agent this Agreement providing for the grant to the Collateral Agent for the benefit of the Secured Parties of a security interest in all of the personal
property of the Grantor to secure all of the Grantor’s Obligations (as defined below) under the Securities Purchase Agreement, the Notes and the other Transaction Documents;
and

supplemented, amended and restated or otherwise modified from time to time, the “Collateral Agency Agreement”); and

WHEREAS, the Grantor, the Buyers and the Collateral Agent are parties to that certain Collateral Agency Agreement dated as of the date hereof (as amended,

WHEREAS,  capitalized  terms  used  herein  and  not  otherwise  defined  in  this Agreement  are  used  in  this Agreement  as  defined  in  the  Securities  Purchase
Agreement. Further, unless otherwise defined in this Agreement or in the Securities Purchase Agreement, terms defined in  Article 8 or 9 of the UCC (as defined below) are used in
this Agreement as such terms are defined in such Article 8 or 9. “UCC” means the Uniform Commercial Code as in effect from time to time in the State of New York; provided that, if
perfection or the effect of perfection or non-perfection or the priority of the security interest in any  Collateral is governed by the  Uniform  Commercial  Code as in effect in a
jurisdiction other than the State of New York, “UCC” means the Uniform Commercial Code as in effect from time to time in such other jurisdiction for purposes of the provisions
hereof relating to such perfection, effect of perfection or non-perfection or priority.

 
 
 
 
 
 
 
 
 
 
 
Grantor hereby agrees with the Collateral Agent for the ratable benefit of the Secured Parties as follows:

NOW, THEREFORE, in consideration of the premises and in order to induce the Buyers to purchase the Notes under the Securities Purchase Agreement, the

1.            Grant of Security. Grantor hereby grants to the Collateral Agent, for the ratable benefit of the Secured Parties, a security interest in all of
Grantor’s tangible and intangible assets, whether real or personal property, now or hereafter acquired, including without limitation all of Grantor’s right, title and interest in and to
the following (collectively, the “Collateral”):

Section 

(a)         all equipment in all of its forms, including, without limitation, all machinery, tools, motor vehicles, vessels, aircraft, furniture and fixtures, and all
parts thereof and all accessions thereto, including, without limitation, computer programs and supporting information that constitute equipment within the meaning of the UCC
(any and all such property being the “Equipment”);

(b)         all inventory in all of its forms, including, without limitation, (i) all raw materials, work in process, finished goods and materials used or consumed
in the manufacture, production, preparation or shipping thereof, (ii) goods in which Grantor has an interest in mass or a joint or other interest or right of any kind (including,
without limitation, goods in which Grantor has an interest or right as consignee) and (iii) goods that are returned to or repossessed or stopped in transit by Grantor), and all
accessions thereto and products thereof and documents therefor, including, without limitation, computer programs and supporting information that constitute inventory within the
meaning of the UCC (any and all such property being the “Inventory”);

(c)         all accounts (including, without limitation, health-care-insurance receivables), chattel paper (including, without limitation, tangible chattel paper
and  electronic  chattel  paper),  instruments  (including,  without  limitation,  promissory  notes),  deposit  accounts  (other  than  Excluded Accounts  (defined  below)),  letter-of-credit
rights, general intangibles (including, without limitation, payment intangibles) and other Obligations of any kind, whether or not arising out of or in connection with the sale or
lease of goods or the rendering of services and whether or not earned by performance, and all rights now or hereafter existing in and to all supporting Obligations and in and to all
security agreements, mortgages, Liens, leases, letters of credit and other contracts securing or otherwise relating to the foregoing property (any and all of such accounts, chattel
paper,  instruments,  deposit  accounts,  letter-of-credit  rights,  general  intangibles  and  other  Obligations,  to  the  extent  not  referred  to  in clause  (d),  (e)  or (f)  below,  being  the
“Receivables,” and any and all such supporting Obligations, security agreements, mortgages, Liens, leases, letters of credit and other contracts being the “Related Contracts”);

(d)          the following (the “Security Collateral”):

(i)       the all of the shares of capital stock of (or other ownership or profit interests in, including partnership, membership or trust interests) in
any entity (“Equity Interests”) listed on Part I of Schedule I (Investment Property) hereto, and the certificates, if any, representing such additional shares or other Equity Interests,
and all dividends, distributions, return of capital, cash, instruments and other property from time to time received, receivable or otherwise distributed in respect of or in exchange
for any or all of such shares or other Equity Interests and all warrants, rights or options issued thereon or with respect thereto;

-2-

 
 
 
 
 
 
 
 
 
 
 
(ii)       the indebtedness listed on Part II of Schedule I (Investment Property) hereto and all additional indebtedness now or from time to time
owed to Grantor (such indebtedness being the “Pledged Debt”) and the instruments, if any, evidencing such indebtedness, and all interest, cash, instruments and other property
from time to time received, receivable or otherwise distributed in respect of or in exchange for any or all of such indebtedness; and

(iii)              all  other  investment  property  (including,  without  limitation,  all  (A)  securities,  whether  certificated  or  uncertificated,  (B)  security
entitlements, (C) securities accounts, (D) commodity contracts and (E) commodity accounts) in which Grantor has now, or acquires from time to time hereafter, any right, title or
interest in any manner, and the certificates or instruments, if any, representing or evidencing such investment property, and all dividends, distributions, return of capital, interest,
cash, instruments and other property from time to time received, receivable or otherwise distributed in respect of or in exchange for any or all of such investment property and all
warrants, rights or options issued thereon or with respect thereto;

(e)          each of the agreements listed on Schedule III (Assigned Agreements) attached hereto, in each case as such agreements may be amended,
restated, amended and restated, supplemented or otherwise modified from time to time (collectively, the “Assigned Agreements ”), including, without limitation, (w) all rights of
Grantor to receive moneys due and to become due under or pursuant to the Assigned Agreements, (x) all rights of Grantor to receive proceeds of any insurance, indemnity,
warranty or guaranty with respect to the Assigned Agreements, (y) claims of Grantor for damages arising out of or for breach of or default under the Assigned Agreements and
(z) the right of Grantor to terminate the Assigned Agreements, to perform thereunder and to compel performance and otherwise exercise all remedies thereunder (all such Collateral
being the “Agreement Collateral”);

(f)          the following (collectively, the “Account Collateral”):

(including, without limitation, all cash equivalents), and all certificates and instruments, if any, from time to time representing or evidencing the Deposit Accounts;

(i)       the deposit accounts listed on Schedule II (Deposit Accounts) hereto and all funds and financial assets from time to time credited thereto

Collateral Agent for or on behalf of Grantor in substitution for or in addition to any or all of the then existing Account Collateral; and

(ii)       all promissory notes, certificates of deposit, checks and other instruments from time to time delivered to or otherwise possessed by the

in respect of or in exchange for any or all of the then existing Account Collateral;

(iii)       all interest, dividends, distributions, cash, instruments and other property from time to time received, receivable or otherwise distributed

-3-

 
 
 
 
 
 
 
 
 
 
 
(g)          the following (collectively, the “Intellectual Property Collateral”):

improvements thereto (“Patents”);

(i)       all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all

(ii)       all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and
other source identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent
that, and solely during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under
applicable federal law), together, in each case, with the goodwill symbolized thereby (“Trademarks”);

thereof, whether registered or unregistered (“Copyrights”);

(iii)       all copyrights, including, without limitation, copyrights in Computer Software (as hereinafter defined), internet web sites and the content

(iv)       all computer software, programs and databases (including, without limitation, source code, object code and all related applications and
data files), firmware and documentation and materials relating thereto, together with any and all maintenance rights, service rights, programming rights, hosting rights, test rights,
improvement rights, renewal rights and indemnification rights and any substitutions, replacements, improvements, error corrections, updates and new versions of any of the
foregoing (“Computer Software”);

(v)              all  confidential  and  proprietary  information,  including,  without  limitation,  know-how,  trade  secrets,  manufacturing  and  production
processes and techniques, inventions, research and development information, databases and data, including, without limitation, technical data, financial, marketing and business
data, pricing and cost information, business and marketing plans and customer and supplier lists and information (collectively, “Trade Secrets”), and all other intellectual, industrial
and intangible property of any type, including, without limitation, industrial designs and mask works;

(vi)              all  registrations  and  applications  for  registration  for  any  of  the  foregoing,  including,  without  limitation,  those  registrations  and
applications for registration set forth in Schedule IV (Intellectual Property) attached hereto, together with all reissues, divisions, continuations, continuations-in-part, extensions,
renewals and reexaminations thereof;

corresponding thereto throughout the world and all other rights of any kind whatsoever of Grantor accruing thereunder or pertaining thereto;

(vii)       all tangible embodiments of the foregoing, all rights in the foregoing provided by international treaties or conventions, all rights

(viii)       all agreements, permits, consents, orders and franchises relating to the license, development, use or disclosure of any of the foregoing
to which Grantor, now or hereafter, is a party or a beneficiary, including, without limitation, the agreements set forth in  Schedule IV (Intellectual Property) attached hereto, (“IP
Agreements”); and

-4-

 
 
 
 
 
 
 
 
 
 
 
 
 
misuse or breach with respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages;

(ix)       any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation,

which the Grantors have complied with the requirements of Section 15, the “Commercial Tort Claims Collateral”);

(h)          the commercial tort claims described in Schedule V (Commercial Tort Claims) attached hereto (together with any commercial tort claims as to

Grantor pertaining to any of the Collateral; and

(i)           all books and records (including, without limitation, customer lists, credit files, printouts and other computer output materials and records) of

(j)                      all  proceeds  of,  collateral  for,  income,  royalties  and  other  payments  now  or  hereafter  due  and  payable  with  respect  to,  and  supporting
Obligations relating to, any and all of the Collateral (including, without limitation, proceeds, collateral and supporting Obligations that constitute property of the types described in
clauses (a) through (i) of this Section 1) and, to the extent not otherwise included, all (A) payments under insurance (whether or not the Collateral Agent is the loss payee thereof),
or any indemnity, warranty or guaranty, payable by reason of loss or damage to or otherwise with respect to any of the foregoing Collateral, and (B) cash;

provided that the term “Collateral” shall at all times exclude all Excluded Assets. “Excluded Assets” means all assets listed on Schedule XI (Excluded Assets) attached hereto.

Section  2.             Security for Obligations. This Agreement and the Collateral granted hereunder secures, in the case of Grantor, the payment of all Obligations
now  or  hereafter  existing,  whether  direct  or  indirect,  absolute  or  contingent,  and  whether  for  principal,  reimbursement  Obligations,  interest,  fees,  premiums,  penalties,
indemnifications, contract causes of action, costs, expenses or otherwise (all such Obligations, the “Secured Obligations”). Without limiting the generality of the foregoing, this
Agreement  secures  the  payment  of  all  amounts  that  constitute  part  of  the  Secured  Obligations  and  would  be  owed  by  Grantor  to  any  Secured  Party  under  the  Transaction
Documents but for the fact that they are unenforceable or not allowable due to the existence of a bankruptcy, reorganization or similar proceeding involving the Grantor. The term
“Obligations” shall mean for so long as the Notes are outstanding the payment by the Company, as and when due and payable (by scheduled maturity, required prepayment,
acceleration, demand or otherwise), of all amounts from time to time owing by it in respect of the Securities Purchase Agreement, the Notes, the Collateral Agency Agreement and
the  other  Transaction  Documents,  including,  without  limitation,  (A)  all  principal  of  and  interest  on  the  Notes  (including,  without  limitation,  all  interest  that  accrues  after  the
commencement of any insolvency proceeding of the  Grantor, whether or not the payment of such interest is unenforceable or is not allowable due to the existence of such
insolvency proceeding), and (B) all fees, commissions, expense reimbursements,  indemnifications  and  all  other  amounts  due  or  to  become  due  under  any  of  the  Transaction
Documents.

-5-

 
 
 
 
 
 
 
 
 
 
Section  3.             Grantor Remains Liable. Anything herein to the contrary notwithstanding, (a) Grantor shall remain liable under the contracts and agreements
included in the Collateral to the extent set forth therein to perform all of its duties and Obligations thereunder to the same extent as if this Agreement had not been executed, (b) the
exercise by the Collateral Agent of any of the rights hereunder shall not release Grantor from any of its duties or Obligations under the contracts and agreements included in the
Collateral and (c) no Secured Party shall have any obligation or liability under the contracts and agreements included in the Collateral by reason of this Agreement or any other
Transaction Document, nor shall any Secured Party be obligated to perform any of the Secured Obligations or duties of any Grantor thereunder or to take any action to collect or
enforce any claim for payment assigned hereunder.

Section 4.             Delivery and Control of Security Collateral.

(a)          All certificates or instruments representing or evidencing Security Collateral shall be delivered to and held by or on behalf of the Collateral
Agent pursuant hereto and shall be in suitable form for transfer by delivery, or shall be accompanied by duly executed instruments of transfer or assignment in blank, all in form
and  substance  reasonably  satisfactory  to  the  Secured  Parties.  The  Collateral Agent  shall  have  the  right  at  any  time  to  exchange  certificates  or  instruments  representing  or
evidencing Security Collateral for certificates or instruments of smaller or larger denominations.

(b)          With respect to any Security Collateral that constitutes an uncertificated security, the Grantor will cause the issuer either (i) to register the
Collateral Agent as the registered owner of such security or (ii) to agree with Grantor and the Collateral Agent that such issuer will comply with instructions with respect to such
security originated by the Collateral Agent without further consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (such
agreement being an “Uncertificated Security Control Agreement”).

(c)          With respect to any Security Collateral that constitutes a security entitlement as to which the financial institution acting as Collateral Agent
hereunder is not the securities intermediary, Grantor will cause the securities intermediary with respect to such security entitlement either (i) to identify in its records the Collateral
Agent as the entitlement holder thereof or (ii) to agree with Grantor and the Collateral Agent that such securities intermediary will comply with entitlement orders originated by the
Collateral Agent without further consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (a “ Securities Account Control
Agreement”).

(d)          The Collateral Agent shall have the right, at any time and without notice to any Grantor, to endorse, assign or otherwise transfer to or to
register in the name of the  Collateral Agent or any of its nominees or endorse for negotiation any or all of the  Security  Collateral, without any indication that such  Security
Collateral is subject to the security interest hereunder, subject only to the revocable rights specified in Section 13(a).

Collateral is subject to the security interest granted hereunder.

(e)          Upon the request of the Collateral Agent, Grantor will notify each issuer of Security Collateral granted by it hereunder that such Security

-6-

 
 
 
 
 
 
 
 
 
 
 
Section 5.            Maintaining the Account Collateral. So long as the Secured Obligations remain outstanding and unpaid:

(a)         Grantor will maintain deposit accounts only with a bank or other depository institution (a “Pledged Account Bank”) that has agreed (or will
agree) with Grantor and the Collateral Agent to comply with instructions originated by the Collateral Agent directing the disposition of funds in such deposit account without the
further consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (a “Deposit Account Control Agreement ”). As a condition
to  the  establishment  and  maintenance  of  deposit  accounts  with  any  such  bank  or  other  depository  institution,  Grantor  shall  have  entered  into  a  Deposit Account  Control
Agreement with such Pledged Account Bank, except with respect to Excluded Accounts (defined below).

Deposit Accounts, to satisfy the Secured Obligations under the Transaction Documents only if an Event of Default shall have occurred and be continuing.

(b)          The Collateral Agent may, without notice to, or consent from, Grantor, give such instructions, transfer, or direct the transfer of, funds from the

payroll, bonuses, other compensation and related expenses and (b) any accounts held outside of the United States of America.

(c)          For the purposes hereof, “Excluded Accounts” means (a) any deposit account that is used solely for escrow, tax, tax withholding, payment of

Section 6.             Representations and Warranties. Grantor represents and warrants as follows:

(a)          As of the Effective Date, Grantor’s exact legal name, location of chief executive office, type of organization, jurisdiction of organization and
organizational identification number (if any) are set forth in Schedule VI (Location, Chief Executive Office, Type of Organization, Jurisdiction of Organization and Organizational
Identification Number); attached hereto. Grantor has no trade names other than as listed on Schedule VI (Location, Chief Executive Office, Type of Organization, Jurisdiction of
Organization and Organizational Identification Number) attached hereto. Within the five years preceding the Effective Date, Grantor has not changed its name, location of its
chief executive office, type of organization, jurisdiction of organization or organizational identification number from those set forth in Schedule VI  (Location,  Chief  Executive
Office, Type of Organization, Jurisdiction of Organization and Organizational Identification Number) attached hereto except as set forth in Schedule VII (Changes in Name,
Location, Etc.) attached hereto.

(b)          Grantor is the legal and beneficial owner of the Collateral granted or purported to be granted by it free and clear of any Lien, claim, option or
right of others, except for the security interest created under this Agreement or permitted hereunder and listed on Schedule X (Permitted Liens). No effective financing statement or
other instrument similar in effect covering all or any part of such Collateral or listing Grantor or any trade name of Grantor as debtor is on file in any recording office, except such as
may have been filed in favor of the Collateral Agent relating to the Transaction Documents or as otherwise permitted under the Securities Purchase Agreement.

-7-

 
 
 
 
 
 
 
 
 
 
 
(c)          All of the Equipment and Inventory of Grantor is located at the places specified therefor in Schedule VIII (Locations of Equipment, Inventory
and Books and Records) attached hereto or at another location as to which Grantor has complied with the requirements of Section 8(a). Grantor has exclusive possession and
control of its Equipment and Inventory.

(d)          All books and records related to the Collateral are located at the places specified therefor in Schedule VIII (Locations of Equipment, Inventory
and  Books  and  Records)  attached  hereto.  Grantor  agrees  to  obtain  a  lien  waiver  and  access  agreement  in  favor  of  the  Collateral Agent,  in  form  and  substance  reasonably
satisfactory to the Secured Parties, with respect to each location in which any books and records are stored. Grantor further agrees to deliver a fully-executed copy of such lien
waiver and access agreement to the Collateral Agent prior to the delivery of such books and records to any other location.

Collateral Agent.

(e)          None of the Receivables or Agreement Collateral is evidenced by a promissory note or other instrument that has not been delivered to the

(f)           If Grantor is an issuer of Security Collateral, Grantor confirms that it has received notice of the security interest granted hereunder.

(g)          The Pledged Equity pledged by Grantor hereunder (if any) has been duly authorized and validly issued and is fully paid and non-assessable.
The Pledged Debt issued by Grantor and pledged by another Grantor hereunder has been duly authorized, authenticated or issued and delivered, is the valid and legally binding
obligation of the issuers thereof and is evidenced by one or more promissory notes (which promissory notes have been delivered to the Collateral Agent).

(h)          The Pledged Equity pledged by Grantor constitutes the percentage of the issued and outstanding Equity Interests of the issuers thereof
indicated on Part I of Schedule I (Investment Property) attached hereto. The Pledged Debt constitutes all of the outstanding indebtedness owed to Grantor by the issuers thereof
and is outstanding in the principal amount indicated, Part II of Schedule I (Investment Property) attached hereto, as of the date hereof and is not in default.

Property).

(i)           Grantor has no investment property, other than the investment property listed on Schedule I (Pledged Equity; Pledged Debt; Investment

(j)           Grantor shall use best efforts to deliver to the Collateral Agent a consent in form and substance reasonably satisfactory to the Secured Parties
from each party to the Assigned Agreements to which the Borrower is a party to the grant of a security interest in such Assigned Agreement pursuant to this Agreement (which
by its terms does not require any such consent or for which a consent was previously obtained).

Accounts and additional deposit accounts as to which Grantor has complied (or as the case may be, will comply) with the applicable requirements of Section 5.

(k)                    Grantor  has  no  deposit  accounts  other  than  the  Deposit Accounts  listed  on Schedule  II  (Deposit  Accounts)  attached  hereto,  Excluded

-8-

 
 
 
 
 
 
 
 
 
 
 
 
 
attached hereto and additional letters of credit as to which Grantor has complied with the requirements of Section 14.

(l)           Grantor is not a beneficiary or assignee under any letter of credit, other than the letters of credit described in Schedule IX (Letters of Credit)

(m)         This Agreement creates in favor of the Collateral Agent for the benefit of the Secured Parties a valid first priority security interest in the
Collateral granted by Grantor, securing the payment of the Secured Obligations; such security interest is subject in priority only to the Permitted Liens and the recording of all
filings and other actions (including, without limitation, (A) actions necessary to obtain control of Collateral as provided in Sections 9-104, 9-105, 9-106 and 9-107 of the UCC and (B)
actions necessary to perfect the Collateral Agent’s security interest with respect to Collateral evidenced by a certificate of title) necessary to perfect the security interest in the
Collateral granted by Grantor have been duly made or taken and are in full force and effect on and after the date hereof.

(n)          No authorization or approval or other action by, and no notice to or filing with, any governmental authority or regulatory body or any other
third party is required for (i) the grant by Grantor of the security interest granted hereunder or for the execution, delivery or performance of this Agreement by Grantor, (ii) the
perfection or maintenance of the security interest created hereunder (including the first priority nature of such security interest), except for the filing of financing and continuation
statements under the UCC, which financing statements shall have been duly filed within 45 days of the Closing, as defined in the Securities Purchase Agreement and, upon filing,
shall be in full force and effect, the recordation of the Intellectual Property Security Agreements referred to in Section 12(c) with the U.S. Patent and Trademark Office and the U.S.
Copyright Office, and the actions described in Section 4 with respect to the Security Collateral, which actions have been taken and are in full force and effect, or (iii) the exercise by
the Collateral Agent of its voting or other rights provided for in this Agreement or the remedies in respect of the Collateral pursuant to this Agreement, except as may be required in
connection with the disposition of any portion of the Security Collateral by laws affecting the offering and sale of securities generally.

(o)          The Inventory that has been produced or distributed by Grantor has been produced in material compliance with all requirements of applicable

law.

(p)          As to itself and its Intellectual Property Collateral:

(i)       The operation of Grantor’s business as currently conducted or as contemplated to be conducted and the use of the Intellectual Property
Collateral in connection therewith, to the best of Grantor’s knowledge, do not conflict with, infringe, misappropriate, dilute, misuse or otherwise violate the intellectual property
rights of any third party.

Intellectual Property Collateral subject only to the terms of the IP Agreements.

(ii)        Grantor is the exclusive owner of all right, title and interest in and to the  Intellectual  Property  Collateral, and is entitled to use all

applications, domain names, trademark registrations and applications, copyright registrations and applications and IP Agreements owned by Grantor as of the date hereof.

(iii)       The Intellectual Property Collateral set forth on Schedule IV (Intellectual Property) attached hereto includes all of the patents, patent

-9-

 
 
 
 
 
 
 
 
 
 
 
 
(iv)       The Intellectual Property Collateral is subsisting and has not been adjudged invalid or unenforceable in whole or in part, and to the best
of Grantor’s knowledge, is valid and enforceable.  Grantor is not aware of any uses of any item of  Intellectual  Property  Collateral that could be expected to lead to such item
becoming invalid or unenforceable.

any of the Intellectual Property Collateral.

(v)       The consummation of the transactions contemplated by the Transaction Documents will not result in the termination or impairment of

commercial tort claims as to which Grantor has complied with the requirements of Section 15.

(q)                    Grantor  has  no  commercial  tort  claims  other  than  those  listed  in Schedule  V  (Commercial  Tort  Claims)  attached  hereto  and  additional

Section 7.             Further Assurances.

(a)          Grantor agrees that from time to time, at the expense of Grantor, Grantor will promptly execute and deliver, or otherwise authenticate, all further
instruments and documents, and take all further action that may be necessary or desirable, or that the Collateral Agent may request, in order to perfect and protect any pledge or
security interest granted or purported to be granted by Grantor hereunder or to enable the Collateral Agent to exercise and enforce its rights and remedies hereunder with respect
to any Collateral of Grantor. Without limiting the generality of the foregoing, Grantor will promptly with respect to Collateral of Grantor: (i) mark conspicuously each document
included in Inventory, each chattel paper included in Receivables, each Related Contract and, at the request of the Collateral Agent, each of its records pertaining to such Collateral
with a legend, in form and substance reasonably satisfactory to the  Secured  Parties, indicating that such document, chattel paper,  Related  Contract, Assigned Agreement or
Collateral is subject to the security interest granted hereby; (ii) if any such Collateral shall be evidenced by a certificate, promissory note or other instrument or chattel paper,
deliver and pledge to the Collateral Agent hereunder such certificate, note or instrument or chattel paper duly indorsed and accompanied by duly executed instruments of transfer
or assignment, all in form and substance reasonably satisfactory to the Secured Parties; (iii) file such financing or continuation statements, or amendments thereto, and such other
instruments or notices, as may be necessary or desirable, or as the Collateral Agent may request, in order to perfect and preserve the security interest granted or purported to be
granted by Grantor hereunder; (iv) take all action to ensure that the Collateral Agent’s security interest is noted on any certificate of title related to any Collateral evidenced by a
certificate  of  title;  (v)  to  cause  the  relevant  depository  institutions,  banks,  financial  intermediaries,  securities  intermediaries  and  issuers  to  execute  and  deliver  such  Deposit
Account Control Agreements, Uncertificated Security Control Agreements, Securities Account Control Agreements and other control agreements, as may be necessary or as the
Collateral Agent may from time to time require; and (vi) deliver to the Collateral Agent evidence that all other actions that the Collateral Agent may deem reasonably necessary or
desirable in order to perfect and protect the security interest granted or purported to be granted by Grantor under this Agreement has been taken.

-10-

 
 
 
 
 
 
 
 
 
(b)          Grantor hereby authorizes the Secured Parties to file one or more financing or continuation statements, and amendments thereto, including,
without limitation, one or more financing statements indicating that such financing statements cover all assets or all personal property (or words of similar effect) of Grantor,
regardless of whether any particular asset described in such financing statements falls within the scope of the UCC or the granting clause of this Agreement. A photocopy or other
reproduction of this Agreement shall be sufficient as a financing statement where permitted by law. Grantor ratifies its authorization for the Secured Parties to have filed such
financing statements, continuation statements or amendments filed prior to the date hereof.

Grantor and such other reports in connection with such Collateral as the Secured Parties may reasonably request, all in reasonable detail.

(c)          Grantor will furnish to the Collateral Agent from time to time statements and schedules further identifying and describing the Collateral of

Section 8.             As to Equipment and Inventory.

(a)          Grantor will keep its Equipment and Inventory (other than Inventory sold in the ordinary course of business and Equipment and Inventory in
transit in the ordinary course of business) at the places therefor specified in Section 6(c) or, upon ten (10) Business Days’ prior written notice to the Collateral Agent, at such other
places designated by Grantor in such notice which shall be an approved warehouse as to which a lien waiver and access agreement has been obtained in favor of and delivered to
the Collateral Agent, in form and substance reasonably satisfactory to the Secured Parties.

(b)          Grantor will cause its Equipment to be maintained and preserved in the same condition, repair and working order as when new, ordinary wear
and tear excepted, and will forthwith, or in the case of any loss or damage to any of such Equipment as soon as practicable after the occurrence thereof, make or cause to be made
all repairs, replacements and other improvements in connection therewith that are desirable to such end.

(c)          Grantor will pay promptly when due all property and other taxes, assessments and governmental charges or levies imposed upon, and all claims
(including, without limitation, claims for labor, materials and supplies) against, its Equipment and Inventory. In producing its Inventory, Grantor will comply, in all material respects,
with all requirements of applicable law.

Section 9.            As to Books and Records.

Grantor will keep its books and records at the places therefor specified in Section 6(d) or, upon ten (10) Business Days’ prior written notice to the Collateral Agent, at such
other places designated by Grantor in such notice which shall be an Approved Warehouse as to which a lien waiver and access agreement has been obtained in favor of and
delivered to the Collateral Agent, in form and substance reasonably satisfactory to the Secured Parties.

-11-

 
 
 
 
 
 
 
 
 
 
 
 
Section 10.           Insurance.

Grantor  shall  maintain  insurance  (including  property  insurance,  lender  loss  payable  endorsements,  etc.)  in  such  amounts  and  covering  such  risks  as  are  reasonably
acceptable to the to the Secured Parties and are usually carried by companies engaged in similar businesses and owning similar properties in the same general areas in which
Grantor operates, including without limitation, insurance on the Collateral.

Section 11.           Post-Closing Changes; Collections on Assigned Agreements, Receivables and Related Contracts.

(a)          Grantor shall not change its name, type of organization, jurisdiction of organization, organizational identification number or location from those
set forth in Section 6(a) of this Agreement without prior written notice to the Collateral Agent. Grantor will hold and preserve its records relating to the Collateral, including, without
limitation, the Assigned Agreements and Related Contracts, and will permit representatives of the Collateral Agent at any time during normal business hours and upon reasonable
notice to inspect and make abstracts from such records and other documents. If any Grantor does not have an organizational identification number and later obtains one, it will
forthwith notify the Collateral Agent of such organizational identification number.

(b)          Except as otherwise provided in this Section 11, Grantor will continue to collect, at its own expense, all amounts due or to become due to
Grantor under the Assigned Agreements, Receivables and Related Contracts. In connection with such collections, Grantor may take such action as Grantor may deem necessary or
advisable to enforce collection of the Assigned Agreements, Receivables and Related Contracts;  provided, however, that the Collateral Agent shall have the right at any time,
upon the occurrence and during the continuance of an Event of Default, to take any steps it or the other Secured Parties may deem necessary or advisable, including but not
limited to, notifying the obligors under any Assigned Agreements, Receivables and Related Contracts of the assignment of such Assigned Agreements, Receivables and Related
Contracts to the Collateral Agent and directing such obligors to make payment of all amounts due or to become due to Grantor thereunder directly to the Collateral Agent and,
upon such notification and at the expense of Grantor, to enforce collection of any such Assigned Agreements, Receivables and Related Contracts, to adjust, settle or compromise
the amount or payment thereof, in the same manner and to the same extent as  Grantor might have done, and to otherwise exercise all rights  with  respect  to  such Assigned
Agreements, Receivables and Related Contracts, including, without limitation, those set forth set forth in Section 9-607 of the UCC. After receipt by any Grantor of the notice from
the Collateral Agent referred to in the proviso to the preceding sentence, Grantor will not adjust, settle or compromise the amount or payment of any Receivable or amount due on
any Assigned Agreement or  Related  Contract, release wholly or partly any obligor thereof or allow any credit or discount thereon.  No  Grantor will permit or consent to the
subordination of its right to payment under any of the Assigned Agreements, Receivables and Related Contracts to any other indebtedness or Obligations of the obligor thereof.

-12-

 
 
 
 
 
 
 
 
 
Section 12.           As to Intellectual Property Collateral.

(a)          No Grantor shall, without the written consent of the Collateral Agent, discontinue use of or otherwise abandon any Intellectual Property
Collateral,  or  abandon  any  right  to  file  an  application  for  patent,  trademark,  or  copyright,  unless  Grantor  shall  have  previously  determined  that  such  use  or  the  pursuit  or
maintenance of such Intellectual Property Collateral is no longer desirable in the conduct of Grantor’s business and that the loss thereof could not reasonably be expected to have
a Material Adverse Change.

(b)          Grantor shall use proper statutory notice in connection with its use of each item of its Intellectual Property Collateral. Except as permitted in
Section 12(a) above, Grantor shall not do or permit any act or knowingly omit to do any act whereby any of its Intellectual Property Collateral may lapse or become invalid or
unenforceable or placed in the public domain.

(c)          With respect to its Intellectual Property Collateral, Grantor agrees to execute or otherwise authenticate an agreement, in substantially the form
set forth in Exhibit A hereto or otherwise in form and substance reasonably satisfactory to the Secured Parties (an “Intellectual Property Security Agreement”), for recording the
security interest granted hereunder to the Collateral Agent in such Intellectual Property Collateral with the U.S. Patent and Trademark Office, the U.S. Copyright Office and any
other governmental authorities necessary to perfect the security interest hereunder in such Intellectual Property Collateral.

(d)          Grantor agrees that should it obtain an ownership interest in any item of the type set forth in Section 1(g) that is not on the date hereof a part of
the Intellectual Property Collateral (“After-Acquired Intellectual Property”) (i) the provisions of this Agreement shall automatically apply thereto, and (ii) any such After-Acquired
Intellectual Property and, in the case of trademarks, the goodwill symbolized thereby, shall automatically become part of the Intellectual Property Collateral subject to the terms and
conditions of this Agreement with respect thereto. Grantor shall give prompt written notice to the Collateral Agent identifying the After-Acquired Intellectual Property, and Grantor
shall execute and deliver to the Collateral Agent with such written notice, or otherwise authenticate, an agreement substantially in the form of Exhibit B hereto or otherwise in form
and substance reasonably satisfactory to the Secured Parties (an “IP Security Agreement Supplement”) covering such After-Acquired Intellectual Property, which IP Security
Agreement Supplement shall be recorded with the U.S. Patent and Trademark Office, the U.S. Copyright Office and any other governmental authorities necessary to perfect the
security interest hereunder in such After-Acquired Intellectual Property.

Section 13.           Voting Rights; Dividends; Etc.. (a) So long as no Event of Default shall have occurred and be continuing:

(i)       Grantor shall be entitled to exercise any and all voting and other consensual rights pertaining to the Security Collateral of Grantor or any
part thereof for any purpose; provided, however, that Grantor will not exercise or refrain from exercising any such right if such action would reasonably be expected to have a
material adverse effect on the value of the Security Collateral or any part thereof.

-13-

 
 
 
 
 
 
 
 
 
 
 
(ii)       Grantor shall be entitled to receive and retain any and all dividends, interest and other distributions paid in respect of the Security
Collateral of Grantor if and to the extent that the payment thereof is not otherwise prohibited by the terms of the Transaction Documents; provided, however, except as otherwise
provided in the Securities Purchase Agreement, any and all dividends, interest and other distributions paid or payable other than in cash in respect of, and instruments and other
property received, receivable or otherwise distributed in respect of, or in exchange for, any Security Collateral shall be, and shall be forthwith delivered to the Collateral Agent to
hold as, Security Collateral and shall, if received by Grantor, be received in trust for the benefit of the Collateral Agent, be segregated from the other property or funds of Grantor
and be forthwith delivered to the Collateral Agent as Security Collateral in the same form as so received (with any necessary endorsement).

(iii)       The Collateral Agent will execute and deliver (or cause to be executed and delivered) to Grantor all such proxies and other instruments
as Grantor may reasonably request for the purpose of enabling Grantor to exercise the voting and other rights that it is entitled to exercise pursuant to paragraph (i) above and to
receive the dividends or interest payments that it is authorized to receive and retain pursuant to paragraph (ii) above.

(b)          Upon the occurrence and during the continuance of an Event of Default:

(i)       All rights of Grantor (x) to exercise or refrain from exercising the voting and other consensual rights that it would otherwise be entitled to
exercise pursuant to Section 13(a)(i) shall, upon notice to Grantor by the Collateral Agent, cease and (y) to receive the dividends, interest and other distributions that it would
otherwise be authorized to receive and retain pursuant to Section 13(a)(ii) shall automatically cease, and all such rights shall thereupon become vested in the Collateral Agent,
which shall thereupon have the sole right to exercise or refrain from exercising such voting and other consensual rights and to receive and hold as  Security  Collateral such
dividends, interest and other distributions.

(ii)       All dividends, interest and other distributions that are received by any Grantor contrary to the provisions of paragraph (i) of this Section
13(b) shall be received in trust for the benefit of the Collateral Agent, shall be segregated from other funds of Grantor and shall be forthwith paid over to the Collateral Agent as
Security Collateral in the same form as so received (with any necessary endorsement).

Section 14.           As to Letter-of-Credit Rights.

(a)          Grantor, by granting a security interest in its Receivables consisting of letter-of-credit rights to the Collateral Agent, intends to (and hereby
does) assign to the Collateral Agent its rights (including its contingent rights) to the proceeds of all Related Contracts consisting of letters of credit of which it is or hereafter
becomes a beneficiary or assignee. Grantor will promptly use commercially reasonable efforts to cause the issuer of each letter of credit in favor of Grantor and each nominated
person (if any) with respect thereto to consent to such assignment of the proceeds thereof pursuant to a consent in form and substance reasonably satisfactory to the Secured
Parties and deliver written evidence of such consent to the Collateral Agent.

-14-

 
 
 
 
 
 
 
 
 
 
 
(b)          Upon the occurrence of an Event of Default, Grantor will, promptly upon request by the Collateral Agent, (i) notify (and Grantor hereby
authorizes the Collateral Agent to notify) the issuer and each nominated person with respect to each of the Related Contracts consisting of letters of credit that the proceeds
thereof have been assigned to the Collateral Agent hereunder and any payments due or to become due in respect thereof are to be made directly to the Collateral Agent or its
designee and (ii) arrange for the Collateral Agent to become the transferee beneficiary of letter of credit.

Section 15.          Commercial Tort Claims. Grantor will promptly give notice to the Collateral Agent of any commercial tort claim that may arise after the date hereof
and will immediately execute or otherwise authenticate a supplement to this Agreement, and otherwise take all necessary action, to subject such commercial tort claim to the first
priority security interest created under this Agreement.

Section 16.           Transfers and Other Liens; Additional Shares.

(a)          Grantor agrees that it will not (i) sell, assign or otherwise dispose of, or grant any option with respect to, any of the Collateral, other than sales,
assignments and other dispositions of Collateral, and options relating to Collateral, permitted under the terms of the Securities Purchase Agreement, or (ii) create or suffer to exist
any Lien upon or with respect to any of the Collateral of Grantor except for the pledge, assignment and security interest created under this Agreement and Liens permitted under
the Securities Purchase Agreement.

(b)          Grantor agrees that it will (i) cause each issuer of the Pledged Equity pledged by Grantor not to issue any Equity Interests or other securities in
addition to or in substitution for the Pledged Equity issued by such issuer, except to Grantor, and (ii) pledge hereunder, immediately upon its acquisition (directly or indirectly)
thereof, any and all additional Equity Interests or other securities.

Section  17.          Collateral Agent Appointed Attorney in Fact . Grantor hereby irrevocably appoints the Collateral Agent as attorney in fact, with full authority in
the place and stead of Grantor and in the name of Grantor or otherwise, from time to time, to take any action and to execute any instrument that the Collateral Agent or the other
Secured Parties may deem necessary or advisable to accomplish the purposes of this Agreement, including, without limitation, upon the occurrence and during the continuance of
an Event of Default, to:

(a)          obtain and adjust insurance required to be paid to the Collateral Agent pursuant to, or in accordance with, Section 9,

respect of any of the Collateral,

(b)          ask for, demand, collect, sue for, recover, compromise, receive and give acquittance and receipts for moneys due and to become due under or in

(c)          receive, indorse and collect any drafts or other instruments, documents and chattel paper, in connection with clause (a) or (b) above, and

(d)          file any claims or take any action or institute any proceedings that the Collateral Agent or the other Secured Parties may deem necessary or
desirable for the collection of any of the Collateral or otherwise to enforce compliance with the terms and conditions of any Assigned Agreement or the rights of the Collateral
Agent with respect to any of the Collateral.

-15-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
18.           Collateral Agent May Perform. If any Grantor fails to perform any agreement contained herein, the Collateral Agent may, but without any
obligation to do so and without notice, itself perform, or cause performance of, such agreement, and the expenses of the Collateral Agent incurred in connection therewith shall be
payable by Grantor under Section 21.

Section 

Section 19.            The Collateral Agent’s Duties.

(a)           The powers conferred on the Collateral Agent hereunder are solely to protect the Secured Parties’ interest in the Collateral and shall not impose
any duty upon it to exercise any such powers. Except for the safe custody of any Collateral in its possession and the accounting for moneys actually received by it hereunder, the
Collateral Agent shall have no duty as to any Collateral, as to ascertaining or taking action with respect to calls, conversions, exchanges, maturities, tenders or other matters
relative to any Collateral, whether or not any Secured Party has or is deemed to have knowledge of such matters, or as to the taking of any necessary steps to preserve rights
against any parties or any other rights pertaining to any Collateral. The Collateral Agent shall be deemed to have exercised reasonable care in the custody and preservation of any
Collateral in its possession if such Collateral is accorded treatment substantially equal to that which it accords its own property.

(b)          Anything contained herein to the contrary notwithstanding, the Collateral Agent may from time to time, when the Collateral Agent in its
discretion deems it to be necessary or advisable, appoint one or more subagents (each a “Subagent”) for the Collateral Agent hereunder with respect to all or any part of the
Collateral. In the event that the Collateral Agent so appoints any Subagent with respect to any Collateral, (i) the assignment and pledge of such Collateral and the security interest
granted in such Collateral by Grantor hereunder shall be deemed for purposes of this Security Agreement to have been made to such Subagent, in addition to the Collateral Agent,
for the ratable benefit of the Secured Parties, as security for the Secured Obligations of Grantor, (ii) such Subagent shall automatically be vested, in addition to the Collateral Agent,
with all rights, powers, privileges, interests and remedies of the Collateral Agent hereunder with respect to such Collateral, and (iii) the term “Collateral Agent,” when used herein in
relation to any rights, powers, privileges, interests and remedies of the Collateral Agent with respect to such Collateral, shall include such Subagent; provided, however, that no
such Subagent shall be authorized to take any action with respect to any such Collateral unless and except to the extent expressly authorized in writing by the Collateral Agent.

-16-

 
 
 
 
 
 
 
 
Section 20.            Remedies. If any Event of Default shall have occurred and be continuing:

(a)           The Collateral Agent may exercise in respect of the Collateral, in addition to other rights and remedies provided for herein or otherwise available
to it, all the rights and remedies of a secured party upon default under the UCC (whether or not the UCC applies to the affected Collateral) and also may: (i) require Grantor to, and
Grantor hereby agrees that it will at its expense and upon request of the Collateral Agent forthwith, to the extent commercially feasible, assemble all or part of the Collateral as
directed by the Collateral Agent and make it available to the Collateral Agent at a place and time to be designated by the Collateral Agent that is reasonably convenient to both
parties; (ii) without notice except as specified below or as otherwise required pursuant to Section 9-611 of the UCC, sell the Collateral or any part thereof in one or more parcels at
public or private sale, at any of the Collateral Agent’s offices or elsewhere, for cash, on credit or for future delivery, and upon such other terms as are in accordance with applicable
law; (iii) occupy any premises owned or leased by any of the Grantors where the Collateral or any part thereof is assembled or located for a reasonable period in order to effectuate
its rights and remedies hereunder or under law; and (iv) exercise any and all rights and remedies of any of the Grantors under or in connection with the Collateral, or otherwise in
respect of the Collateral, including, without limitation, (A) any and all rights of Grantor to demand or otherwise require payment of any amount under, or performance of any
provision of, the Assigned Agreements, the Receivables, the Related Contracts and the other Collateral, (B) withdraw, or cause or direct the withdrawal, of all funds with respect to
the Account Collateral and (C) exercise all other rights and remedies with respect to the Assigned Agreements, the Receivables, the Related Contracts and the other Collateral,
including, without limitation, those set forth in Section 9-607 of the UCC. Grantor agrees that, to the extent notice of sale shall be required by law, at least ten (10) days’ notice to
Grantor of the time and place of any public sale or the time after which any private sale is to be made shall constitute reasonable notification. The Collateral Agent shall not be
obligated  to  make  any  sale  of  Collateral  regardless  of  notice  of  sale  having  been  given.  The  Collateral Agent  may  adjourn  any  public  or  private  sale  from  time  to  time  by
announcement at the time and place fixed therefor, and such sale may, without further notice (except as otherwise required by Section 9-611 of the UCC), be made at the time and
place to which it was so adjourned.

(b)          Any cash held by or on behalf of the Collateral Agent and all cash proceeds received by or on behalf of the Collateral Agent in respect of any
sale of, collection from, or other realization upon all or any part of the Collateral may, in the discretion of the Collateral Agent, be held by the Collateral Agent as collateral for the
benefit of the Secured Parties against, all or any part of the Secured Obligations. Any surplus of such cash or cash proceeds held by or on the behalf of the Collateral Agent and
remaining after payment in full of all the Secured Obligations shall be paid over to Grantor or to whomsoever may be lawfully entitled to receive such surplus.

(c)          All payments received by any Grantor under or in connection with any Assigned Agreement or otherwise in respect of the Collateral shall be
received in trust for the benefit of the Collateral Agent, shall be segregated from other funds of Grantor and shall be forthwith paid over to the Collateral Agent in the same form as
so received (with any necessary endorsement).

(d)          [RESERVED].

(e)          In the event of any sale or other disposition of any of the Intellectual Property Collateral of Grantor, the goodwill symbolized by any Trademarks
subject  to  such  sale  or  other  disposition  shall  be  included  therein,  and  Grantor  shall  supply  to  the  Collateral Agent  or  its  designee  Grantor’s  know-how  and  expertise,  and
documents and things relating to any Intellectual Property Collateral subject to such sale or other disposition, and Grantor’s customer lists and other records and documents
relating to such Intellectual Property Collateral and to the manufacture, distribution, advertising and sale of products and services of Grantor.

-17-

 
 
 
 
 
 
 
 
 
 
agrees that, upon request of the Collateral Agent, Grantor will, at its own expense:

(f)           If the Collateral Agent shall exercise its right to sell all or any of the Security Collateral of any Grantor pursuant to this Section 20, Grantor

(i)       execute and deliver, and cause each issuer of such Security Collateral contemplated to be sold and the directors and officers thereof to
execute and deliver, all such instruments and documents, and do or cause to be done all such other acts and things, as may be necessary or, in the opinion of the Collateral Agent,
advisable to register such Security Collateral under the provisions of the Securities Act of 1933 (as amended from time to time, the “Securities Act”), to cause the registration
statement relating thereto to become effective and to remain effective for such period as prospectuses are required by law to be furnished and to make all amendments and
supplements thereto and to the related prospectus that, in the opinion of the Collateral Agent or the other Secured Parties, are necessary or advisable, all in conformity with the
requirements of the Securities Act and the rules and regulations of the Securities and Exchange Commission applicable thereto;

governmental approvals for the sale of such Security Collateral, as requested by the Collateral Agent;

(ii)              use  its  best  efforts  to  qualify  the  Security  Collateral  under  the  state  securities  or  “Blue  Sky”  laws  and  to  obtain  all  necessary

statement that will satisfy the provisions of Section 11(a) of the Securities Act;

(iii)              cause  each  such  issuer  of  such  Security  Collateral  to  make  available  to  its  security  holders,  as  soon  as  practicable,  an  earnings

or the other Secured Parties, advisable to enable the Collateral Agent to effect the sale of such Security Collateral upon such terms as are in accordance with applicable law; and

(iv)       provide the Collateral Agent with such other information and projections as may be necessary or, in the opinion of the Collateral Agent

thereof valid and binding and in compliance with applicable law.

(v)       do or cause to be done all such other acts and things as may be necessary to make such sale of such Security Collateral or any part

(g)          The Collateral Agent is authorized, in connection with any sale of the Security Collateral pursuant to this Section 20, to deliver or otherwise
disclose to any prospective purchaser of the Security Collateral: (i) any registration statement or prospectus, and all supplements and amendments thereto, prepared pursuant to
subsection (f)(i) above; (ii) any information and projections provided to it pursuant to subsection (f)(iv) above; and (iii) any other information in its possession relating to such
Security Collateral.

(h)          Grantor acknowledges the impossibility of ascertaining the amount of damages that would be suffered by the Secured Parties by reason of the
failure by Grantor to perform any of the covenants contained in subsection (f) above and, consequently, agrees that, if Grantor shall fail to perform any of such covenants, it will
pay,  as  liquidated  damages  and  not  as  a  penalty,  an  amount  equal  to  the  value  of  the  Security  Collateral  on  the  date  the  Collateral Agent  shall  demand  compliance  with
subsection (f) above.

-18-

 
 
 
 
 
 
 
 
 
 
 
 
Section 21.           Indemnity and Expenses.

(a)          Grantor agrees to indemnify, defend and save and hold harmless each Secured Party and each of their Affiliates and their Related Parties (each,
an “Indemnified Party”) from and against, and shall pay on demand, any and all claims, damages, losses, liabilities and expenses (including, without limitation, reasonable fees and
expenses of counsel) that may be incurred by or asserted or awarded against any  Indemnified  Party, in each case arising out of or in connection with or resulting from this
Agreement (including, without limitation, enforcement of this Agreement); provided that such indemnity shall not, as to any Indemnified Party, be available to the extent that such
losses, claims, damages, liabilities or related expenses (x) are determined by a court of competent jurisdiction by final and nonappealable judgment to have resulted from the bad
faith, gross negligence or willful misconduct of such Indemnified Party or any of its officers, directors or employees, or (y) arising from disputes solely among the Collateral Agent,
the  Buyers  and/or  their  transferees  (other  than  in  respect  of  disputes  against  an  Indemnitee  in  its  capacity  as  Collateral Agent  or  any  similar  role  under  the  Transaction
Documents).

(b)          Without limiting the foregoing clause (a), Grantor will upon demand pay to the Collateral Agent the amount of any and all (1) reasonable
expenses, including, without limitation, the reasonable fees and expenses of its counsel and of any experts and agents, that the Collateral Agent may incur in connection with
(i) the administration of this Agreement, and (ii) the custody, preservation, use or operation of, or the sale of, collection from or other realization upon, any of the Collateral of
Grantor, and (2) expenses, including, without limitation, the fees and expenses of its counsel and of any experts and agents, that the Collateral Agent may incur in connection with
(i) the exercise or enforcement of any of the rights of the Collateral Agent or the other Secured Parties hereunder or (ii) the failure by Grantor to perform or observe any of the
provisions hereof.

Section 22.         Amendments; Waivers; Additional Grantors; Etc. No amendment or waiver of any provision of this Agreement, and no consent to any departure
by any Grantor herefrom, shall in any event be effective unless the same shall be in writing and signed by the Collateral Agent, and then such waiver or consent shall be effective
only in the specific instance and for the specific purpose for which given. No failure on the part of the Collateral Agent to exercise, and no delay in exercising any right hereunder,
shall operate as a waiver thereof; nor shall any single or partial exercise of any such right preclude any other or further exercise thereof or the exercise of any other right.

Section 

23.          Notices,  Etc.  Except  as  otherwise  provided  herein,  whenever  it  is  provided  herein  that  any  notice,  demand,  request,  consent,  approval,
declaration or other communication shall or may be given to or served upon any of the parties by any other party, or whenever any of the parties desires to give and serve upon
any other party any communication with respect to this Agreement, each such notice, demand, request, consent, approval, declaration or other communication shall be in writing
and shall be given in the manner and to the address, and deemed received, as provided for in accordance with the terms of the Collateral Agency Agreement. Delivery by email or
facsimile of an executed counterpart of any amendment, supplement or waiver of any provision of this Agreement or any Schedule or Exhibit relating thereto shall be effective as
delivery of an original executed counterpart thereof.

-19-

 
 
 
 
 
 
 
 
 
Section  24.           Continuing Security Interest. This Agreement shall create a continuing security interest in the Collateral and shall (a) remain in full force and
effect until the indefeasible payment in full in cash of the Secured Obligations, (b) be binding upon Grantor, its successors and assigns and (c) inure, together with the rights and
remedies of the Collateral Agent hereunder, to the benefit of the Secured Parties and their respective successors, transferees and assigns.

Section 25.            Release; Termination.

(a)           Upon any sale, lease, transfer or other disposition of any item of Collateral of Grantor (other than sales of Inventory in the ordinary course of
business) in accordance with the terms of the Transaction Documents, the Collateral Agent will, at Grantor’s expense, execute and deliver to Grantor such documents as Grantor
shall reasonably request to evidence the release of such item(s) of Collateral from the assignment and security interest granted hereby; provided, however, that (i) at the time of
such request and such release no Event of Default shall have occurred and be continuing, (ii) Grantor shall have delivered to the Collateral Agent, at least ten (10) Business Days
prior to the date of the proposed release, a written request for release describing the item of Collateral and the terms of the sale, lease, transfer or other disposition in reasonable
detail,  including,  without  limitation,  the  price  thereof  and  any  expenses  in  connection  therewith,  together  with  a  form  of  release  for  execution  by  the  Collateral Agent  and  a
certificate of Grantor to the effect that the transaction is in compliance with the Transaction Documents and as to such other matters as the Collateral Agent may request, (iii) the
proceeds of any such sale, lease, transfer or other disposition required to be applied, or any payment to be made in connection therewith, shall, to the extent so required, be paid or
made to, or in accordance with the instructions of, the Collateral Agent, and (iv) the Collateral Agent shall have received written direction from the Buyers in accordance with the
Collateral Agency Agreement.

(b)          Upon the indefeasible payment in full in cash of the Secured Obligations, other than any unasserted contingent Obligations, the pledge and
security interest granted hereby shall terminate and all rights to the Collateral shall revert to Grantor. Upon any such termination, the Secured Parties will, at the Grantor’s expense,
execute and deliver to Grantor such documents as Grantor shall reasonably request to evidence such termination.

Section 26.          Execution in Counterparts. This Agreement may be executed in any number of counterparts, each of which when so executed shall be deemed to
be an original and all of which taken together shall constitute one and the same agreement. Delivery of an executed counterpart of a signature page to this Agreement by email or
facsimile shall be effective as delivery of an original executed counterpart of this Agreement.

-20-

 
 
 
 
 
 
 
 
 
Section 27.            Governing Law; Jurisdiction; Waiver of Jury Trial, Etc. 

(a )           GOVERNING LAW. THIS AGREEMENT AND ANY CLAIMS, CONTROVERSY, DISPUTE OR CAUSE OF ACTION (WHETHER IN TORT OR
OTHERWISE) BASED ON, ARISING OUT OF OR RELATING TO THIS GUARANTY AND THE TRANSACTIONS CONTEMPLATED HEREBY SHALL BE GOVERNED BY, AND
CONSTRUED IN ACCORDANCE WITH, THE LAW OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS (OTHER THAN SECTIONS 5-1401 AND 5-
1402 OF THE NEW YORK GENERAL OBLIGATIONS LAWS).

(b)          SUBMISSION TO JURISDICTION. GRANTOR IRREVOCABLY AND UNCONDITIONALLY SUBMITS, FOR ITSELF AND ITS PROPERTY, TO
THE  NONEXCLUSIVE  JURISDICTION  OF  THE  COURTS  OF  THE  STATE  OF  NEW  YORK  SITTING  IN  NEW  YORK  COUNTY  OR  OF  THE  UNITED  STATES  FOR  THE
SOUTHERN DISTRICT OF SUCH STATE, AND ANY APPELLATE COURT FROM ANY THEREOF, IN ANY ACTION OR PROCEEDING ARISING OUT OF OR RELATING TO
THIS AGREEMENT, OR FOR RECOGNITION OR ENFORCEMENT OF ANY JUDGMENT, AND EACH OF THE PARTIES HERETO IRREVOCABLY AND UNCONDITIONALLY
AGREES THAT ALL CLAIMS IN RESPECT OF ANY SUCH ACTION OR PROCEEDING MAY BE HEARD AND DETERMINED IN SUCH NEW YORK COURT OR, TO THE
FULLEST EXTENT PERMITTED BY APPLICABLE LAW, IN SUCH FEDERAL COURT. EACH OF THE PARTIES HERETO AGREES THAT A FINAL JUDGMENT IN ANY SUCH
ACTION OR PROCEEDING SHALL BE CONCLUSIVE AND MAY BE ENFORCED IN OTHER JURISDICTIONS BY SUIT ON THE JUDGMENT OR IN ANY OTHER MANNER
PROVIDED  BY  LAW.  NOTHING  IN  THIS  AGREEMENT  SHALL  AFFECT  ANY  RIGHT  THAT  THE  COLLATERAL  AGENT  OR  ANY  OTHER  SECURED  PARTY  MAY
OTHERWISE HAVE TO BRING ANY ACTION OR PROCEEDING RELATING TO THIS AGREEMENT AGAINST ANY GRANTOR OR ITS PROPERTIES IN THE COURTS OF
ANY JURISDICTION.

( c )          WAIVER  OF  VENUE.  GRANTOR  IRREVOCABLY AND  UNCONDITIONALLY  WAIVES,  TO  THE  FULLEST  EXTENT  PERMITTED  BY
APPLICABLE LAW, ANY OBJECTION THAT IT MAY NOW OR HEREAFTER HAVE TO THE LAYING OF VENUE OF ANY ACTION OR PROCEEDING ARISING OUT OF OR
RELATING TO THIS AGREEMENT IN ANY COURT REFERRED TO IN PARAGRAPH (b) OF THIS SECTION. GRANTOR HEREBY IRREVOCABLY WAIVES, TO THE FULLEST
EXTENT PERMITTED BY APPLICABLE LAW, THE DEFENSE OF AN INCONVENIENT FORUM TO THE MAINTENANCE OF SUCH ACTION OR PROCEEDING IN ANY SUCH
COURT.

NOTICES IN SECTION 23.

( d )          SERVICE OF PROCESS. GUARANTOR HERETO IRREVOCABLY CONSENTS TO SERVICE OF PROCESS IN THE MANNER PROVIDED FOR

( e )          WAIVER  OF  JURY  TRIAL.  GUARANTOR  HERETO  HEREBY  IRREVOCABLY  WAIVES,  TO  THE  FULLEST  EXTENT  PERMITTED  BY

APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN ANY LEGAL PROCEEDING DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THIS
AGREEMENT  OR  THE  TRANSACTIONS  CONTEMPLATED  HEREBY  (WHETHER  BASED  ON  CONTRACT,  TORT  OR  ANY  OTHER  THEORY).  EACH  PARTY  HERETO
(A) CERTIFIES THAT NO REPRESENTATIVE, AGENT OR ATTORNEY OF ANY OTHER PERSON HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER
PERSON WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE FOREGOING WAIVER AND (B) ACKNOWLEDGES THAT IT AND THE OTHER PARTIES
HERETO HAVE BEEN INDUCED TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS IN THIS SECTION.

SIGNATURE PAGE FOLLOWS

-21-

 
 
 
 
 
 
 
 
 
 
 
written.

IN WITNESS WHEREOF, Grantor has caused this Agreement to be duly executed and delivered by its officer thereunto duly authorized as of the date first above

APPLIED DNA SCIENCES, INC.,
a Delaware corporation

/s/ Beth Jantzen

By:
Name: Beth Jantzen, CPA
Title:

Chief Financial Officer

SIGNATURES CONTINUE ON NEXT PAGE

Signature Page to Security Agreement 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ACCEPTED AND AGREED
as of the date first written above by:

DELAWARE TRUST COMPANY,
as Collateral Agent

/s/ Alan R. Halpern

By:
Name:   Alan R. Halpern
Title:

Vice President

Signature Page to Security Agreement

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Exhibit A to the
Security Agreement

FORM OF INTELLECTUAL PROPERTY SECURITY AGREEMENT

This INTELLECTUAL PROPERTY SECURITY AGREEMENT (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “IP Security Agreement”) dated October 19, 2018 is made by APPLIED DNA SCIENCES, INC. a Delaware corporation (the “Grantor”), in favor of DELAWARE TRUST
COMPANY, a Delaware corporation, as collateral agent (the “Collateral Agent”) for the Secured Parties (as defined in the Security Agreement referred to below).

otherwise modified from time to time, the “Securities Purchase Agreement”) with the Buyers party thereto.

WHEREAS, Grantor is party to the Securities Purchase Agreement dated as of August 31, 2018 (as amended, restated, amended and restated, supplemented or

WHEREAS, pursuant to the Securities Purchase Agreement, the Grantor has executed and delivered that certain Security Agreement dated as of the date hereof
made by the Grantor to the Collateral Agent for the benefit of the Secured Parties (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “Security Agreement”; the capitalized terms defined therein and not otherwise defined herein being used herein as therein defined).

WHEREAS, under the terms of the Security Agreement, the Grantor has granted to the Collateral Agent, for the ratable benefit of the Secured Parties, a security
interest in, among other property, certain intellectual property of the Grantor, and have agreed as a condition thereof to execute this IP Security Agreement for recording with the
U.S. Patent and Trademark Office, the United States Copyright Office and other governmental authorities.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Grantor agrees as follows:

SECTION 1.     Grant of Security. Grantor hereby grants to the Collateral Agent for the ratable benefit of the Secured Parties a security interest in all of Grantor’s

right, title and interest in and to the following (the “Collateral”):

(i)       all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all improvements

thereto, including, without limitation, those set forth in Schedule A hereto (the “Patents”);

(ii)       all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and other source
identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent that, and solely
during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under applicable federal
law), together, in each case, with the goodwill symbolized thereby, including, without limitation, those set forth in Schedule B hereto (the “Trademarks”);

 
 
 
 
 
 
 
 
 
 
 
 
 
 
(iii)       all copyrights, including, without limitation, copyrights in Computer Software (as hereinafter defined), internet web sites and the content thereof, whether
registered  or  unregistered,  including,  without  limitation,  the  copyright  registrations  and  applications  and  exclusive  copyright  licenses  set  forth  in Schedule  C  hereto  (the
“Copyrights”);

(iv)       all reissues, divisions, continuations, continuations-in-part, extensions, renewals and reexaminations of any of the foregoing, all rights in the foregoing
provided by international treaties or conventions, all rights corresponding thereto throughout the world and all other rights of any kind whatsoever of Grantor accruing thereunder
or pertaining thereto;

(v)       any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation, misuse or breach with

respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages; and

(vi)       any and all proceeds of, collateral for, income, royalties and other payments now or hereafter due and payable with respect to, and supporting Obligations

(as defined in the Security Agreement) relating to, any and all of the Collateral of or arising from any of the foregoing.

SECTION  2.    Security for Obligations. The grant of a security interest in the Collateral by Grantor under this IP Security Agreement secures the payment of all
Secured Obligations now or hereafter existing under or in respect of the Transaction Documents, whether direct or indirect, absolute or contingent, and whether for principal,
reimbursement obligations, interest, premiums, penalties, fees, indemnifications, contract causes of action, costs, expenses or otherwise. Without limiting the generality of the
foregoing, this IP Security Agreement secures, as to Grantor, the payment of all amounts that constitute part of the Secured Obligations and that would be owed by Grantor to any
Secured  Party  under  the  Transaction  Documents  but  for  the  fact  that  such  Secured  Obligations  are  unenforceable  or  not  allowable  due  to  the  existence  of  a  bankruptcy,
reorganization or similar proceeding involving Grantor.

and any other applicable government officer record this IP Security Agreement.

SECTION 3.    Recordation. Grantor authorizes and requests that the Register of Copyrights, the Commissioner for Patents and the Commissioner for Trademarks

deemed to be an original and all of which taken together shall constitute one and the same agreement.

SECTION  4.    Execution in Counterparts. This IP Security Agreement may be executed in any number of counterparts, each of which when so executed shall be

SECTION  5.   Grants, Rights and Remedies. This IP Security Agreement has been entered into in conjunction with the provisions of the Security Agreement.
Grantor does hereby acknowledge and confirm that the grant of the security interest hereunder to, and the rights and remedies of, the Collateral Agent with respect to the Collateral
are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated herein by reference as if fully set forth herein.

LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS.

SECTION  6.   GOVERNING  LAW.  THIS  IP  SECURITY AGREEMENT  SHALL  BE  GOVERNED  BY, AND  CONSTRUED  IN ACCORDANCE  WITH,  THE

[remainder of page intentionally blank]

-2-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, Grantor has caused this IP Security Agreement to be duly executed and delivered by its officer thereunto duly authorized as of the date

first above written.

APPLIED DNA SCIENCES, INC.

By
Name:
Title:

Address for Notices:

 
 
 
 
 
 
 
        
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Exhibit B to the
Security Agreement

FORM OF INTELLECTUAL PROPERTY SECURITY AGREEMENT SUPPLEMENT

This INTELLECTUAL PROPERTY SECURITY AGREEMENT SUPPLEMENT (as amended, restated, amended and restated, supplemented or otherwise modified
from time to time, the “IP Security Agreement Supplement”) dated __________, 20__, is made by APPLIED DNA SCIENCES, INC. a Delaware corporation (the “Grantors”) in favor
of DELAWARE TRUST COMPANY, a Delaware corporation, as collateral agent (the “ Collateral Agent”) for the Secured Parties (as defined in the Security Agreement referred to
below).

otherwise modified from time to time, the “Securities Purchase Agreement”) with the Buyers party thereto.

WHEREAS, Grantor is party to the Securities Purchase Agreement dated as of [August 31], 2018 (as amended, restated, amended and restated, supplemented or

WHEREAS, pursuant to the Securities Purchase Agreement, the Grantor has executed and delivered that certain Security Agreement dated as of October 19, 2018
made by the Grantor to the Collateral Agent for the benefit of the Secured Parties (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “Security Agreement”) and that certain Intellectual Property Security Agreement dated [insert date of Intellectual Property Security Agreement] made by the Grantor to
the Collateral Agent for the benefit of the Secured Parties (as amended, restated, amended and restated, supplemented or otherwise modified from time to time, the “IP  Security
Agreement”; the capitalized terms defined therein and not otherwise defined herein being used herein as therein defined).

WHEREAS, under the terms of the Security Agreement, the Grantor has granted to the Collateral Agent, for the ratable benefit of the Secured Parties, a security
interest in the Additional Collateral (as defined in Section 1 below) of the Grantor and has agreed as a condition thereof to execute this IP Security Agreement Supplement for
recording with the U.S. Patent and Trademark Office, the United States Copyright Office and other governmental authorities.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Grantor agrees as follows:

SECTION 1. Grant of Security. Each Grantor hereby grants to the Collateral Agent, for the ratable benefit of the Secured Parties, a security interest in all of such

Grantor’s right, title and interest in and to the following (the “Additional Collateral”):

(i)       all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all improvements

thereto, including, without limitation, those set forth in Schedule A hereto (the “Patents”);

(ii)       all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and other source
identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent that, and solely
during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under applicable federal
law), together, in each case, with the goodwill symbolized thereby, including, without limitation, those set forth in Schedule B hereto (the “Trademarks”);

 
 
 
 
 
 
 
 
 
 
 
 
 
 
(ii)       all copyrights, including, without limitation, copyrights in Computer Software (as hereinafter defined), internet web sites and the content thereof, whether
registered  or  unregistered,  including,  without  limitation,  the  copyright  registrations  and  applications  and  exclusive  copyright  licenses  set  forth  in Schedule  C  hereto  (the
“Copyrights”);

(iii)       all reissues, divisions, continuations, continuations-in-part, extensions, renewals and reexaminations of any of the foregoing, all rights in the foregoing
provided by international treaties or conventions, all rights corresponding thereto throughout the world and all other rights of any kind whatsoever of such Grantor accruing
thereunder or pertaining thereto;

(iv)       all any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation, misuse or breach

with respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages; and

(v)       any and all proceeds of, collateral for, income, royalties and other payments now or hereafter due and payable with respect to, and supporting Obligations

(as defined in the Security Agreement) relating to, any and all of the foregoing or arising from any of the foregoing.

SECTION 2. Security for Obligations. The grant of a security interest in the Additional Collateral by the Grantor under this IP Security Agreement Supplement
secures the payment of all Secured Obligations now or hereafter existing under or in respect of the Loan Documents, whether direct or indirect, absolute or contingent, and whether
for principal, reimbursement Obligations, interest, premiums, penalties, fees, indemnifications, contract causes of action, costs, expenses or otherwise.

Trademarks and any other applicable government officer to record this IP Security Agreement Supplement.

SECTION  3. Recordation.  The  Grantor  authorizes  and  requests  that  the  Register  of  Copyrights,  the  Commissioner  for  Patents  and  the  Commissioner  for

SECTION  4. Grants, Rights and Remedies. This IP Security Agreement Supplement has been entered into in conjunction with the provisions of the Security
Agreement. The Grantor does hereby acknowledge and confirm that the grant of the security interest hereunder to, and the rights and remedies of, the Collateral Agent with
respect to the Additional Collateral are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated herein by reference as if fully set forth
herein.

WITH, THE LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS.

SECTION  5. GOVERNING LAW.  THIS  IP  SECURITY AGREEMENT  SUPPLEMENT  SHALL  BE  GOVERNED  BY, AND  CONSTRUED  IN ACCORDANCE

-2-

 
 
 
 
 
 
 
 
 
 
 
 
authorized as of the date first above written.

IN  WITNESS  WHEREOF,  the  Grantor  has  caused  this  IP  Security Agreement  Supplement  to  be  duly  executed  and  delivered  by  its  officer  thereunto  duly

By

Name:
Title:

Address for Notices:

-3-

 
 
 
 
        
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Part I: None.

Part II: None.

SCHEDULE I

Investment Property

 
 
 
 
 
 
 
 
·

·

Bank of America, Operating Account, Account #004831291068

Bank of America, Money Market Account, Account #483043680826

SCHEDULE II

Deposit Accounts

 
 
 
 
 
 
 
 
None.

SCHEDULE III

Assigned Agreements

 
 
 
 
 
 
 
SCHEDULE IV

Intellectual Property

COPYRIGHTS: None.

TRADEMARKS:

Docket No.
2542-83
2542-82
2542-47
2542-75
2542-95
2542-89
2542-84
2542-89A

PATENTS:

Client Ref 
No.

8251-61
2542-75

Country
United States
United States
United States
United States
United States
United States
United States
United States

 Application 
Date
12/13/2016
12/20/2016
06/09/2008
12/09/2016
5/16/2017
3/6/2017
12/23/2016
8/16/2017

Application 
No.
87/267,216
87/275,103
77/494,134
87/263,954
87/451,220
87/360,183
87/279,792
87/571,726

 Registration 
Date

 Registration No.

12/12/2017
01/05/2010
05/23/2017

10/17/2017
08/22/2017

5,356,414
3,735,415
5,209,527

5,313,762
5,269,735

Status
Filed
Registered
Registered
Registered
Filed
Registered
Registered
Filed

Country

United States

Status

Granted

Application 
No.

Application 
Date

12/384,554

04/06/2009

Title
METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE
SYSTEM

Patent No.

Grant Date

8,163,489

04/24/2012

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
None.

SCHEDULE V

Commercial Tort Claims

 
 
 
 
 
 
 
Location of Chief Executive Office, Type of Organization, Jurisdiction of Organization and Organizational Identification Number

Location of Chief Executive Office: 50 Health Sciences Drive, Stony Brook, NY 11790

SCHEDULE VI

Type of Organization: Corporation

Jurisdiction of Organization: Delaware

·

·

·

· Organization Identification Number: 59-2262718

 
 
 
 
 
 
 
 
 
 
None.

SCHEDULE VII

Changes in Name, Location, Etc.

 
 
 
 
 
 
 
·

50 Health Sciences Drive, Stony Brook, NY 11790

SCHEDULE VIII

Locations of Equipment, Inventory and Books and Records

 
 
 
 
 
 
 
None.

SCHEDULE IX

Letters of Credit

 
 
 
 
 
 
 
None.

SCHEDULE X

Permitted Liens

 
 
 
 
 
 
 
SCHEDULE XI

Excluded Assets

·

·

·

the Equity Interests in Applied DNA Sciences India Private Limited, a corporation formed under the laws of India, owned by the Grantor;

the Equity Interests in APDN (B.V.I.) Inc., a corporation formed under the laws of the British Virgin Islands, owned by the Grantor; and

all Excluded Accounts.

 
 
 
 
 
 
 
 
 
 
 
Exhibit 10.41

EXECUTION VERSION

FIRST AMENDMENT TO SECURITY AGREEMENT

This FIRST AMENDMENT TO SECURITY AGREEMENT (this “ Amendment”), dated as of November 26, 2018, is between APPLIED DNA SCIENCES, INC., a Delaware
corporation (the “Grantor”)  and DELAWARE TRUST COMPANY, a Delaware corporation, as collateral agent (together with its successors and assigns, in such capacity, the
“Collateral Agent”) for the benefit of the undersigned investors (each, a “Buyer” and collectively, the “Buyers”; the Buyers and the Collateral Agent are collectively, together with
their successors and assigns, referred to herein as the “Secured Parties”) and the other Secured Parties.

WITNESSETH:

WHEREAS,  the  Grantor  and  the  Collateral Agent  are  parties  to  that  certain  Security Agreement,  dated  as  of  October  19,  2018  (as  amended,  amended  and  restated,
supplemented or otherwise modified from time to time, the “Security Agreement”), whereby the Grantor granted a security interest in substantially all of its tangible and intangible
assets, whether real or personal property, now or hereafter acquired (the “Collateral”), to the Collateral Agent for the ratable benefit of the Secured Parties;

WHEREAS, the Collateral Agent, the Grantor, APDN (B.V.I.) Inc. and the Buyers are parties that certain Collateral Agency Agreement, dated as of October 19, 2018 (as
amended, amended and restated, supplemented or otherwise modified from time to time, the “Collateral Agency Agreement”), whereby, among other things, the Buyers appointed
the Collateral Agent as the Secured Parties’ representative and agent with respect to the Collateral, and the Collateral Agent agreed to take such actions as directed in writing from
time to time by the Buyers, including with respect to the perfection of the Collateral Agent’s security interest in the Collateral;

WHEREAS,  the  Grantor  has  requested  and  the  Secured  Parties,  by  their  execution  and  acknowledgement  hereof,  have  each  agreed,  subject  to  the  terms  of  this

Amendment, to amend the Security Agreement as provided herein; and

NOW, THEREFORE, the parties hereto hereby agree as follows, for good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged:

1 .       Definitions. Capitalized terms used and not otherwise defined in this Amendment shall have the respective meanings given to such terms in the Security

Agreement.

2.       Amendment to the Security Agreement. The parties hereto agree, intending to be legally bound, that Section 5(a) (Maintaining the Account Collateral) of

the Security Agreement is hereby amended and restated in its entirely as follows:

(a)       Grantor will maintain deposit accounts with a bank or other depository institution (a “Pledged Account Bank”) that will agree with Grantor and the
Collateral Agent to comply with instructions originated by the Collateral Agent directing the disposition of funds in such deposit account without the further
consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (a “Deposit Account Control Agreement ”). The
Secured Parties may require the Grantor to enter into a Deposit Account Control Agreement with such Pledged Account Bank with respect to any such existing
deposit accounts, except with respect to Excluded Accounts, upon thirty (30) Business Days prior written notice to the Grantor.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
3.       Ratification. Except as specifically modified herein, the terms of the Security Agreement and the Collateral Agency Agreement shall remain in full force and
effect. This Amendment shall be construed in connection with and as a part of the Security Agreement and, except as expressly amended by this Amendment, all terms, conditions,
covenants, representations and warranties contained in the Security Agreement and the Collateral Agency Agreement are hereby ratified and shall be and remain in full force and
effect. Any and all notices, requests, certificates and other instruments executed and delivered after the execution and delivery of this Amendment may refer to the  Security
Agreement without making specific reference to this Amendment, but nevertheless all such references shall include this Amendment.

4 .       Parties Bound.  This Amendment shall be binding on and inure to the benefit of (i) the  Grantor and (ii) the  Secured  Parties, as well as each of their

respective heirs, executors, administrators, legal representatives, successors and assigns, except as otherwise expressly provided for herein.

5 .       Counterparts and Signatures. This Amendment may be executed in any number of counterparts, each of which when so executed and delivered shall be
deemed to be an original, and all of which taken together shall constitute but one and the same instrument. The transmission or receipt of a facsimile or similar communication being
a reproduction of a party’s signature or initial shall produce the same legal result as the transmission or receipt of an original signature or initial.

6 .       Severability of Provisions. Any provision of this Amendment which is prohibited and unenforceable in any jurisdiction shall, as to such jurisdiction, be
ineffective to the extent of such prohibitive or enforceability without invalidating the remaining provisions hereof or affecting the validity or enforceability of such provisions in
any other jurisdiction.

7.       Section Headings. The Section headings used in this Amendment are for convenience only and shall not affect the construction of this Amendment.

8.       Governing Law. This Amendment shall be governed by and construed in accordance with the laws of the State of New York.

9 .       Instruction to Administrative Agent . Each of the Buyers, by its acknowledgement hereof, hereby directs the Collateral Agent to execute and deliver this
Amendment, and authorizes the Collateral Agent to take action as agent on its behalf and to exercise such powers and discretion under the Security Agreement, the Collateral
Agency Agreement and the other Transaction Documents (as defined in the Collateral Agency Agreement) as are delegated to the Collateral Agent by the terms thereof, together
with such powers and discretion as are reasonably incidental. This Section 9 is solely for the benefit of the Collateral Agent and the Buyers and neither the Grantor nor any other
Person shall have rights as a third party beneficiary of the provisions in this Section 9.

10.       Costs and Expenses. Without limiting any expense or indemnity provisions set forth in the Security Agreement, the Collateral Agency Agreement or any
other Transaction Document, the Grantor agrees to pay on demand all reasonable and documented out-of-pocket expenses, fees, and disbursements (including reasonable and
documented attorneys’ fees and expenses) of the Collateral Agent and the Buyers in connection with the negotiation, preparation, execution, delivery and administration of this
Amendment.

[remainder of page intentionally left blank]

 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, the parties have executed this Amendment as of the day and year first above written.

GRANTOR:

APPLIED DNA SCIENCES, INC., a Delaware corporation

By:
/s/ Beth Jantzen
Print Name:   Beth Jantzen, CPA
Its:   Chief Financial Officer

[Signatures Continue on Following Page]

Signature Page to First Amendment to Security Agreement

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
COLLATERAL AGENT

DELAWARE TRUST COMPANY,
as Collateral Agent

/s/ Alan R. Halpern

By:
Name: Alan R. Halpern
Title: Vice President

[Signatures Continue on Following Page]

Signature Page to First Amendment to Security Agreement

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ACKNOWLEDGED AND CONSENTED TO BY BUYERS:

By:
/s/ James A. Hayward
Print Name:  James A. Hayward

By:  
/s/ Judith Murrah
Print Name:  Judith Murrah

By:  
/s/ Yavoc Shamash
Print Name:  Yavoc Shamash

By:  
/s/ Robert Catell
Print Name:  Robert Catell

/s/ Elizabeth Schmalz Ferguson
By:  
Print Name:  Elizabeth Schmalz Ferguson

By:  
/s/ Gregg Baldwin
Print Name:  Gregg Baldwin

/s/ William Montgomery 11/8/18

By:  
Print Name:  William Montgomery

By:  
/s/ Johnette van Eeden
Print Name:  Johnette van Eeden

By:  
/s/ John Cartier
Print Name:  John Cartier

Signature Page to First Amendment to Security Agreement

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ACKNOWLEDGED AND CONSENTED TO BY BUYERS (continued):

Delabarta II

By:  
/s/ John F. Bitzer III
Print Name:  John F. Bitzer III
Title:  President

The Rodgers Living Trust Dated April 7, 1995

/s/ Jay Rodgers

By:  
Print Name:  Jay D. Rodgers
Title:  Trustee

Signature:

/s/ Jay Rodgers
Jay Rodgers (Nov 23, 2018)

Email:

jayrodgers2@gmail.com

Signature Page to First Amendment to Security Agreement

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Exhibit 10.42

EXECUTION VERSION

GUARANTY AND SECURITY AGREEMENT

dated October 19, 2018

by

the Grantor referred to herein

as Grantor

to

Delaware Trust Company

as Collateral Agent

 
 
 
 
 
 
 
 
 
 
 
 
TABLE OF CONTENTS

PAGE

Section 1.

Section 2.

Section 3.

Section 4.

Section 5.

Section 6.

Section 7.

Section 8.

Section 9.

Guarantee

Guaranty Absolute.

Waiver and Acknowledgments.

Subrogation

Continuing Guaranty

Grant of Security

Guaranteed Obligations

Grantor Remains Liable

Delivery and Control of Security Collateral.

Section 10.

Maintaining the Account Collateral

Section 11.

Representations and Warranties

Section 12.

Further Assurances.

Section 13.

As to Equipment and Inventory.

Section 14.

As to Books and Records.

Section 15.

Insurance.

Section 16.

Post-Closing Changes; Collections on Assigned Agreements, Receivables and Related Contracts.

Section 17.

As to Intellectual Property Collateral.

Section 18.

Voting Rights; Dividends; Etc.

Section 19.

As to Letter-of-Credit Rights.

Section 20.

Commercial Tort Claims

Section 21.

Transfers and Other Liens; Additional Shares.

Section 22.

Collateral Agent Appointed Attorney in Fact

Section 23.

Collateral Agent May Perform

-i-

2

2

4

4

5

5

8

9

9

10

10

13

14

15

15

15

16

17

18

18

18

18

19

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
19

20

22

23

23

23

23

24

24

Section 24.

The Collateral Agent’s Duties.

Section 25.

Remedies

Section 26.

Indemnity and Expenses.

Section 27.

Amendments; Waivers; Additional Grantors; Etc.

Section 28.

Notices, Etc.

Section 29.

Continuing Security Interest

Section 30.

Release; Termination.

Section 31.

Execution in Counterparts

Section 32.

Governing Law; Jurisdiction; Waiver of Jury Trial, Etc.

Schedules:

Schedule I
Schedule II
Schedule III
Schedule IV
Schedule V
Schedule VI
Schedule VII
Schedule VIII
Schedule IX
Schedule X
Schedule XI

Exhibits:

Exhibit A
Exhibit B

-
-
-
-
-
-
-
-
-
-

-
-

Investment Property
Deposit Accounts
Assigned Agreements
Intellectual Property
Commercial Tort Claims
Location, Chief Executive Office, Type of Organization, Jurisdiction of Organization and Organizational Identification Number
Changes in Name, Location, Etc.
Locations of Equipment, Inventory and Books and Records
Letters of Credit
Permitted Liens
Excluded Assets

Form of Intellectual Property Security Agreement
Form of IP Security Agreement Supplement

-ii-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GUARANTY AND SECURITY AGREEMENT

GUARANTY AND SECURITY AGREEMENT (as amended, supplemented, amended and restated or otherwise modified from time to time, this “ Agreement”)
dated  October  19,  2018  made  by APDN  (B.V.I.)  Inc.,  a  corporation  organized  under  the  laws  of  the  British  Virgin  Islands  (the  “ Grantor”),  in  favor  of  DELAWARE  TRUST
COMPANY, a Delaware corporation, as collateral agent (together with any successor collateral agent, in such capacity, the “ Collateral Agent”) for the benefit of the investors
listed on the Schedule of Buyers (each a “Buyer” and collectively, the “Buyers”; the Buyers and the Collateral Agent are collectively, with their successors and assigns, the
“Secured Parties”)) set forth in the Securities Purchase Agreement, dated as of August 31, 2018 (as amended, amended and restated, supplemented or otherwise modified from time
to time) and the other Secured Parties (the “Securities Purchase Agreement”).

PRELIMINARY STATEMENTS

WHEREAS, APPLIED  DNA  SCIENCES,  INC.,  a  Delaware  corporation  (the  “Company”)  and  each  Buyer  are  parties  to  the  Securities  Purchase Agreement,
pursuant to which the Company shall be required to sell, and the Buyers shall purchase or have rights to purchase, on a several and not joint basis the principal amount of the
Notes issued pursuant thereto (as such Notes may be amended, amended and restated, supplemented or otherwise modified from time to time, the “Notes”); and

WHEREAS, the Grantor is a wholly owned subsidiary of the Company and shall derive substantial benefit from the transactions contemplated in connection with

the Securities Purchase Agreement;

WHEREAS, it is a condition precedent to the Buyers purchasing the Notes pursuant to the Securities Purchase Agreement that the Grantor shall have executed
and delivered to the Collateral Agent this Agreement providing for (i) the guaranty of the Guaranteed Obligations (as defined below) and (ii) the grant to the Collateral Agent for
the benefit of the Secured Parties of a security interest in all of the personal property of the Grantor to secure all of the Guaranteed Obligations (as defined below) under the
Securities Purchase Agreement, the Notes and the other Transaction Documents; and

WHEREAS, the Grantor, the Company, the Buyers and the Collateral Agent are parties to that certain Collateral Agency Agreement dated as of the date hereof

(as amended, supplemented, amended and restated or otherwise modified from time to time, the “Collateral Agency Agreement”); and

WHEREAS,  capitalized  terms  used  herein  and  not  otherwise  defined  in  this Agreement  are  used  in  this Agreement  as  defined  in  the  Securities  Purchase
Agreement. Further, unless otherwise defined in this Agreement or in the Securities Purchase Agreement, terms defined in  Article 8 or 9 of the UCC (as defined below) are used in
this Agreement as such terms are defined in such Article 8 or 9. “UCC” means the Uniform Commercial Code as in effect from time to time in the State of New York; provided that, if
perfection or the effect of perfection or non-perfection or the priority of the security interest in any  Collateral is governed by the  Uniform  Commercial  Code as in effect in a
jurisdiction other than the State of New York, “UCC” means the Uniform Commercial Code as in effect from time to time in such other jurisdiction for purposes of the provisions
hereof relating to such perfection, effect of perfection or non-perfection or priority.

 
 
 
 
 
 
 
 
 
 
 
NOW, THEREFORE, in consideration of the premises and in order to induce the Buyers to purchase the Notes under the Securities Purchase Agreement, the

Grantor hereby agrees with the Collateral Agent for the ratable benefit of the Secured Parties as follows:

Section 1.             Guarantee.

(a)          Grantor hereby absolutely, unconditionally and irrevocably guarantees the punctual payment when due, whether at scheduled maturity or by
acceleration, demand or otherwise, of all obligations now or hereafter existing (including, without limitation, any extensions, modifications, substitutions, amendments or renewals
of any or all of the foregoing obligations), whether direct or indirect, absolute or contingent, and whether for principal, interest, premiums, fees, commissions, reimbursements,
indemnities, contract causes of action, costs, expenses or otherwise (such obligations being the “Guaranteed Obligations”), and agrees to pay any and all expenses (including,
without limitation, fees and expenses of counsel) incurred by any Secured Party in enforcing any rights under this Agreement or any other Transaction Document with respect to
the Guaranteed Obligations. Without limiting the generality of the foregoing, Grantor’s liability shall extend to all amounts that constitute part of the Guaranteed Obligations and
would be owed by the Company to any Secured Party under or in respect of the Transaction Documents but for the fact that they are unenforceable or not allowable due to the
existence of a bankruptcy, reorganization or similar proceeding involving the Company.

(b)         Grantor hereby unconditionally and irrevocably agrees that in the event any payment shall be required to be made to any Secured Party under
this Agreement or any other guaranty, Grantor will contribute, to the maximum extent permitted by law, such amounts to any other guarantor so as to maximize the aggregate
amount paid to the Secured Parties under or in respect of the Transaction Documents with respect to the Guaranteed Obligations.

Section  2.             Guaranty Absolute. Grantor guarantees that the Guaranteed Obligations will be paid strictly in accordance with the terms of the Transaction
Documents, regardless of any law, regulation or order now or hereafter in effect in any jurisdiction affecting any of such terms or the rights of any Secured Party with respect
thereto. The obligations of Grantor under or in respect of this Agreement are primary and independent of or any other obligations of any other Party under or in respect of the
Transaction Documents, and a separate action or actions may be brought and prosecuted against Grantor to enforce this Agreement, irrespective of whether any action is brought
against the Company or any other Party or whether the Company or any other Party is joined in any such action or actions. The liability of Grantor under this Agreement shall be
irrevocable, absolute and unconditional irrespective of, and Grantor hereby irrevocably waives, any defenses it may now have or hereafter acquire in any way relating to, any or all
of the following:

-2-

 
 
 
 
 
 
 
 
 
(a)          any lack of validity or enforceability of any Transaction Document or any agreement or instrument relating thereto;

(b)          any change in the time, manner or place of payment of, or in any other term of, all or any of the Guaranteed Obligations or any other obligations
of any other  Person under or in respect of the  Transaction  Documents, or any other amendment or waiver of or any consent to departure from any  Transaction  Document,
including, without limitation, any increase in the Guaranteed Obligations resulting from the issuance of additional Notes by the Company or otherwise;

or waiver of, or consent to departure from, any other guaranty, for all or any of the Guaranteed Obligations;

(c)          any taking, exchange, release or non-perfection of any Collateral (as defined below) or any other collateral, or any taking, release or amendment

(d)          any manner of application of Collateral or any other collateral, or proceeds thereof, to all or any of the Guaranteed Obligations, or any manner of
sale or other disposition of any Collateral or any other collateral for all or any of the Guaranteed Obligations or any other obligations of the Grantor and the Company under the
Transaction Documents or any other assets of Grantor or any other Person;

(e)          any change, restructuring or termination of the entity structure or existence of Grantor;

(f)                    any  failure  of  any  Secured  Party  to  disclose  to  the  Grantor  any  information  relating  to  the  business,  condition  (financial  or  otherwise),
operations, performance, properties or prospects of the Company now or hereafter known to such Secured Party (Grantor waiving any duty on the part of the Secured Parties to
disclose such information);

guarantor or surety with respect to the Guaranteed Obligations; or

(g)          the failure of any other Person to execute or deliver any other guaranty or agreement or the release or reduction of liability of any other

(h)          any other circumstance (including, without limitation, any statute of limitations but excluding indefeasible payment or performance in full of the
Guaranteed Obligations) or any existence of or reliance on any representation by any Secured Party that might otherwise constitute a defense available to, or a discharge of, any
Grantor or any other guarantor or surety.

This Guaranty shall continue to be effective or be reinstated, as the case may be, if at any time any payment of any of the Guaranteed Obligations is rescinded or must otherwise be
returned by any Secured Party or any other Person upon the insolvency, bankruptcy or reorganization of the Company or any other Person or otherwise, all as though such
payment had not been made.

-3-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Section 3.             Waiver and Acknowledgments.

(a)          Grantor hereby unconditionally and irrevocably waives promptness, diligence, notice of acceptance, presentment, demand for performance,
notice of nonperformance, default, acceleration, protest or dishonor and any other notice with respect to any of the Guaranteed Obligations and this Agreement (other than such
notices required by the express terms of this Agreement) and any requirement that any Secured Party protect, secure, perfect or insure any Lien or any property subject thereto or
exhaust any right or take any action against the Company or any other Person or any Collateral;

continuing in nature and applies to all Guaranteed Obligations, whether existing now or in the future;

(b)                    Grantor  hereby  unconditionally  and  irrevocably  waives  any  right  to  revoke  this Agreement  and  acknowledges  that  this Agreement  is

(c)          Grantor hereby unconditionally and irrevocably waives (i) any defense arising by reason of any claim or defense based upon an election of
remedies  by  any  Secured  Party  that  in  any  manner  impairs,  reduces,  releases  or  otherwise  adversely  affects  the  subrogation,  reimbursement,  exoneration,  contribution  or
indemnification rights of Grantor or other rights of Grantor to proceed against any other guarantor or any other Person or any Collateral and (ii) any defense based on any right of
set-off or counterclaim against or in respect of the obligations of such Grantor hereunder.

(d)          Grantor hereby unconditionally and irrevocably waives any duty on the part of any Secured Party to disclose to the Grantor any matter, fact or
thing relating to the business, condition (financial or otherwise), operations, performance, properties or prospects of any of such Guarantor’s Subsidiaries now or hereafter known
by such Secured Party any manner of application of Collateral or any other collateral, or proceeds thereof, to all or any of the Guaranteed Obligations, or any manner of sale or
other  disposition  of  any  Collateral  or  any  other  collateral  for  all  or  any  of  the  Guaranteed  Obligations  or  any  other  obligations  of  the  Grantor  and  the  Company  under  the
Transaction Documents or any other assets of Grantor or any other Person;

Transaction Documents and that the waivers set forth in above are knowingly made in contemplation of such benefits;

(e)                    Grantor  acknowledges  that  it  will  receive  substantial  direct  and  indirect  benefits  from  the  issuance  of  the  Notes  contemplated  by  the

Section 

4.             Subrogation. Guarantor hereby unconditionally and irrevocably agrees not to exercise any rights that it may now have or hereafter acquire
against the Company or any other guarantor that arise from the existence, payment, performance or enforcement of the Grantor’s obligations under or in respect of this Agreement
or any other Transaction Document, including, without limitation, any right of subrogation, reimbursement, exoneration, contribution or indemnification and any right to participate
in any claim or remedy of any Secured Party against the Company or any other guarantor or any Collateral, whether or not such claim, remedy or right arises in equity or under
contract, statute or common law, including, without limitation, the right to take or receive from the Company or any other guarantor, directly or indirectly, in cash or other property
or by set-off or in any other manner, payment or security on account of such claim, remedy or right, unless and until all of the Guaranteed Obligations and all other amounts
payable under this Agreement shall have been paid in full in cash and the Notes shall have expired or been terminated. If any amount shall be paid to Grantor in violation of the
immediately preceding sentence at any time prior to the payment in full in cash of the Guaranteed Obligations and all other amounts payable under this Agreement, such amount
shall be received and held in trust for the benefit of the Secured Parties, shall be segregated from other property and funds of Grantor and shall forthwith be paid or delivered to the
Secured Parties in the same form as so received (with any necessary endorsement or assignment) to be credited and applied to the Guaranteed Obligations and all other amounts
payable  under  this Agreement,  whether  matured  or  unmatured,  in  accordance  with  the  terms  of  the  Transaction  Documents,  or  to  be  held  as  Collateral  for  any  Guaranteed
Obligations  or  other  amounts  payable  under  this Agreement  thereafter  arising.  If  (i)  Grantor  shall  make  payment  to  any  Secured  Party  of  all  or  any  part  of  the  Guaranteed
Obligations and (ii) all of the Guaranteed Obligations and all other amounts payable under this Agreement shall have been paid in full in cash, the Secured Parties will, at Grantor’s
request and expense, execute and deliver to  Grantor appropriate documents, without recourse and without representation or warranty, necessary to evidence the transfer by
subrogation to Grantor of an interest in the Guaranteed Obligations resulting from such payment made by such Grantor pursuant to this Agreement.

-4-

 
 
 
 
 
 
 
 
 
 
 
5.            Continuing Guaranty. This Agreement provides for a continuing guaranty and shall (a) remain in full force and effect until the indefeasible
payment in full in cash of the Guaranteed Obligations and all other amounts payable under this Agreement, (b) be binding upon Grantor, its successors and assigns, and (c) inure
to the benefit of and be enforceable by the Secured Parties and their successors, permitted transferees and permitted assigns.

Section 

6.             Grant of Security. Grantor hereby grants to the Collateral Agent, for the ratable benefit of the Secured Parties, a security interest in all of
Grantor’s tangible and intangible assets, whether real or personal property, now or hereafter acquired, including without limitation all of Grantor’s right, title and interest in and to
the following (collectively, the “Collateral”):

Section 

(a)          all equipment in all of its forms, including, without limitation, all machinery, tools, motor vehicles, vessels, aircraft, furniture and fixtures, and all
parts thereof and all accessions thereto, including, without limitation, computer programs and supporting information that constitute equipment within the meaning of the UCC
(any and all such property being the “Equipment”);

(b)          all inventory in all of its forms, including, without limitation, (i) all raw materials, work in process, finished goods and materials used or
consumed in the manufacture, production, preparation or shipping thereof, (ii) goods in which Grantor has an interest in mass or a joint or other interest or right of any kind
(including, without limitation, goods in which Grantor has an interest or right as consignee) and (iii) goods that are returned to or repossessed or stopped in transit by Grantor),
and all accessions thereto and products thereof and documents therefor, including, without limitation, computer programs and supporting information that constitute inventory
within the meaning of the UCC (any and all such property being the “Inventory”);

-5-

 
 
 
 
 
 
 
 
(c)          all accounts (including, without limitation, health-care-insurance receivables), chattel paper (including, without limitation, tangible chattel paper
and  electronic  chattel  paper),  instruments  (including,  without  limitation,  promissory  notes),  deposit  accounts  (other  than  Excluded Accounts  (defined  below)),  letter-of-credit
rights, general intangibles (including, without limitation, payment intangibles) and other Obligations of any kind, whether or not arising out of or in connection with the sale or
lease of goods or the rendering of services and whether or not earned by performance, and all rights now or hereafter existing in and to all supporting Obligations and in and to all
security agreements, mortgages, Liens, leases, letters of credit and other contracts securing or otherwise relating to the foregoing property (any and all of such accounts, chattel
paper,  instruments,  deposit  accounts,  letter-of-credit  rights,  general  intangibles  and  other  Obligations,  to  the  extent  not  referred  to  in clause  (d),  (e)  or (f)  below,  being  the
“Receivables,” and any and all such supporting Obligations, security agreements, mortgages, Liens, leases, letters of credit and other contracts being the “Related Contracts”);

(d)          the following (the “Security Collateral”):

(i)          the all of the shares of capital stock of (or other ownership or profit interests in, including partnership, membership or trust interests) in
any entity (“Equity Interests”) listed on Part I of Schedule I (Investment Property) hereto, and the certificates, if any, representing such additional shares or other Equity Interests,
and all dividends, distributions, return of capital, cash, instruments and other property from time to time received, receivable or otherwise distributed in respect of or in exchange
for any or all of such shares or other Equity Interests and all warrants, rights or options issued thereon or with respect thereto;

(ii)         the indebtedness listed on Part II of Schedule I (Investment Property) hereto and all additional indebtedness now or from time to time
owed to Grantor (such indebtedness being the “Pledged Debt”) and the instruments, if any, evidencing such indebtedness, and all interest, cash, instruments and other property
from time to time received, receivable or otherwise distributed in respect of or in exchange for any or all of such indebtedness; and

(iii)                all  other  investment  property  (including,  without  limitation,  all  (A)  securities,  whether  certificated  or  uncertificated,  (B)  security
entitlements, (C) securities accounts, (D) commodity contracts and (E) commodity accounts) in which Grantor has now, or acquires from time to time hereafter, any right, title or
interest in any manner, and the certificates or instruments, if any, representing or evidencing such investment property, and all dividends, distributions, return of capital, interest,
cash, instruments and other property from time to time received, receivable or otherwise distributed in respect of or in exchange for any or all of such investment property and all
warrants, rights or options issued thereon or with respect thereto;

(e)          each of the agreements listed on Schedule III (Assigned Agreements) attached hereto, in each case as such agreements may be amended,
restated, amended and restated, supplemented or otherwise modified from time to time (collectively, the “Assigned Agreements ”), including, without limitation, (w) all rights of
Grantor to receive moneys due and to become due under or pursuant to the Assigned Agreements, (x) all rights of Grantor to receive proceeds of any insurance, indemnity,
warranty or guaranty with respect to the Assigned Agreements, (y) claims of Grantor for damages arising out of or for breach of or default under the Assigned Agreements and
(z) the right of Grantor to terminate the Assigned Agreements, to perform thereunder and to compel performance and otherwise exercise all remedies thereunder (all such Collateral
being the “Agreement Collateral”);

-6-

 
 
 
 
 
 
 
 
 
 
 
(f)          the following (collectively, the “Account Collateral”):

thereto (including, without limitation, all cash equivalents), and all certificates and instruments, if any, from time to time representing or evidencing the Deposit Accounts;

(i)          the deposit accounts listed on Schedule II (Deposit Accounts) hereto and all funds and financial assets from time to time credited

Collateral Agent for or on behalf of Grantor in substitution for or in addition to any or all of the then existing Account Collateral; and

(ii)         all promissory notes, certificates of deposit, checks and other instruments from time to time delivered to or otherwise possessed by the

in respect of or in exchange for any or all of the then existing Account Collateral;

(iii)        all interest, dividends, distributions, cash, instruments and other property from time to time received, receivable or otherwise distributed

(g)          the following (collectively, the “Intellectual Property Collateral”):

improvements thereto (“Patents”);

(i)          all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all

(ii)         all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and
other source identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent
that, and solely during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under
applicable federal law), together, in each case, with the goodwill symbolized thereby (“Trademarks”);

content thereof, whether registered or unregistered (“Copyrights”);

(iii)        all copyrights, including, without limitation, copyrights in  Computer  Software (as hereinafter defined), internet web sites and the

(iv)        all computer software, programs and databases (including, without limitation, source code, object code and all related applications and
data files), firmware and documentation and materials relating thereto, together with any and all maintenance rights, service rights, programming rights, hosting rights, test rights,
improvement rights, renewal rights and indemnification rights and any substitutions, replacements, improvements, error corrections, updates and new versions of any of the
foregoing (“Computer Software”);

(v)         all confidential and proprietary information, including, without limitation, know-how, trade secrets, manufacturing and production
processes and techniques, inventions, research and development information, databases and data, including, without limitation, technical data, financial, marketing and business
data, pricing and cost information, business and marketing plans and customer and supplier lists and information (collectively, “Trade Secrets”), and all other intellectual, industrial
and intangible property of any type, including, without limitation, industrial designs and mask works;

-7-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
(vi)                all  registrations  and  applications  for  registration  for  any  of  the  foregoing,  including,  without  limitation,  those  registrations  and
applications for registration set forth in Schedule IV (Intellectual Property) attached hereto, together with all reissues, divisions, continuations, continuations-in-part, extensions,
renewals and reexaminations thereof;

corresponding thereto throughout the world and all other rights of any kind whatsoever of Grantor accruing thereunder or pertaining thereto;

(vii)       all tangible embodiments of the foregoing, all rights in the foregoing provided by international treaties or conventions, all rights

(viii)      all agreements, permits, consents, orders and franchises relating to the license, development, use or disclosure of any of the foregoing
to which Grantor, now or hereafter, is a party or a beneficiary, including, without limitation, the agreements set forth in  Schedule IV (Intellectual Property) attached hereto, (“IP
Agreements”); and

misuse or breach with respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages;

(ix)         any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation,

which the Grantors have complied with the requirements of Section 20, the “Commercial Tort Claims Collateral”);

(h)          the commercial tort claims described in Schedule V (Commercial Tort Claims) attached hereto (together with any commercial tort claims as to

Grantor pertaining to any of the Collateral; and

(i)           all books and records (including, without limitation, customer lists, credit files, printouts and other computer output materials and records) of

(j)                      all  proceeds  of,  collateral  for,  income,  royalties  and  other  payments  now  or  hereafter  due  and  payable  with  respect  to,  and  supporting
Obligations relating to, any and all of the Collateral (including, without limitation, proceeds, collateral and supporting Obligations that constitute property of the types described in
clauses (a) through (i) of this Section 6) and, to the extent not otherwise included, all (A) payments under insurance (whether or not the Collateral Agent is the loss payee thereof),
or any indemnity, warranty or guaranty, payable by reason of loss or damage to or otherwise with respect to any of the foregoing Collateral, and (B) cash;

provided that the term “Collateral” shall at all times exclude all Excluded Assets. “Excluded Assets” means all assets listed on Schedule XI (Excluded Assets) attached hereto.

Section  7.             Security for Guaranteed Obligations. This Agreement and the Collateral granted hereunder secures, in the case of Grantor, the payment of all
Guaranteed Obligations now or hereafter existing, whether direct or indirect, absolute or contingent, and whether for principal, reimbursement Guaranteed Obligations, interest,
fees, premiums, penalties, indemnifications, contract causes of action, costs, expenses or otherwise (all such Guaranteed Obligations, the “Secured Obligations”). Without limiting
the generality of the foregoing, this Agreement secures the payment of all amounts that constitute part of the Secured Obligations and would be owed by Grantor to any Secured
Party under the Transaction Documents but for the fact that they are unenforceable or not allowable due to the existence of a bankruptcy, reorganization or similar proceeding
involving the Grantor.

-8-

 
 
 
 
 
 
 
 
 
 
 
 
 
Section  8.             Grantor Remains Liable. Anything herein to the contrary notwithstanding, (a) Grantor shall remain liable under the contracts and agreements
included in the Collateral to the extent set forth therein to perform all of its duties and obligations thereunder to the same extent as if this Agreement had not been executed, (b) the
exercise by the Collateral Agent of any of the rights hereunder shall not release Grantor from any of its duties or obligations under the contracts and agreements included in the
Collateral and (c) no Secured Party shall have any obligation or liability under the contracts and agreements included in the Collateral by reason of this Agreement or any other
Transaction Document, nor shall any Secured Party be obligated to perform any of the Secured Obligations or duties of Grantor thereunder or to take any action to collect or
enforce any claim for payment assigned hereunder.

Section 9.             Delivery and Control of Security Collateral.

(a)          All certificates or instruments representing or evidencing Security Collateral shall be delivered to and held by or on behalf of the Collateral
Agent pursuant hereto and shall be in suitable form for transfer by delivery, or shall be accompanied by duly executed instruments of transfer or assignment in blank, all in form
and  substance  reasonably  satisfactory  to  the  Secured  Parties.  The  Collateral Agent  shall  have  the  right  at  any  time  to  exchange  certificates  or  instruments  representing  or
evidencing Security Collateral for certificates or instruments of smaller or larger denominations.

(b)          With respect to any Security Collateral that constitutes an uncertificated security, the Grantor will cause the issuer either (i) to register the
Collateral Agent as the registered owner of such security or (ii) to agree with Grantor and the Collateral Agent that such issuer will comply with instructions with respect to such
security originated by the Collateral Agent without further consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (such
agreement being an “Uncertificated Security Control Agreement”).

(c)          With respect to any Security Collateral that constitutes a security entitlement as to which the financial institution acting as Collateral Agent
hereunder is not the securities intermediary, Grantor will cause the securities intermediary with respect to such security entitlement either (i) to identify in its records the Collateral
Agent as the entitlement holder thereof or (ii) to agree with Grantor and the Collateral Agent that such securities intermediary will comply with entitlement orders originated by the
Collateral Agent without further consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (a “ Securities Account Control
Agreement”).

(d)          The Collateral Agent shall have the right, at any time and without notice to any Grantor, to endorse, assign or otherwise transfer to or to
register in the name of the  Collateral Agent or any of its nominees or endorse for negotiation any or all of the  Security  Collateral, without any indication that such  Security
Collateral is subject to the security interest hereunder, subject only to the revocable rights specified in Section 18(a).

-9-

 
 
 
 
 
 
 
 
 
 
Collateral is subject to the security interest granted hereunder.

(e)          Upon the request of the Collateral Agent, Grantor will notify each issuer of Security Collateral granted by it hereunder that such Security

Section 10.          Maintaining the Account Collateral. So long as the Secured Obligations remain outstanding and unpaid:

(a)          Grantor will maintain deposit accounts only with a bank or other depository institution (a “Pledged Account Bank”) that has agreed (or will
agree) with Grantor and the Collateral Agent to comply with instructions originated by the Collateral Agent directing the disposition of funds in such deposit account without the
further consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (a “Deposit Account Control Agreement ”). As a condition
to  the  establishment  and  maintenance  of  deposit  accounts  with  any  such  bank  or  other  depository  institution,  Grantor  shall  have  entered  into  a  Deposit Account  Control
Agreement with such Pledged Account Bank, except with respect to Excluded Accounts (defined below).

Deposit Accounts, to satisfy the Secured Obligations under the Transaction Documents only if an Event of Default shall have occurred and be continuing.

(b)          The Collateral Agent may, without notice to, or consent from, Grantor, give such instructions, transfer, or direct the transfer of, funds from the

payroll, bonuses, other compensation and related expenses and (b) any accounts held outside of the United States of America.

(c)          For the purposes hereof, “Excluded Accounts” means (a) any deposit account that is used solely for escrow, tax, tax withholding, payment of

Section 11.           Representations and Warranties. Grantor represents and warrants as follows:

(a)          As of the Effective Date, Grantor’s exact legal name, location of chief executive office, type of organization, jurisdiction of organization and
organizational identification number (if any) are set forth in Schedule VI (Location, Chief Executive Office, Type of Organization, Jurisdiction of Organization and Organizational
Identification Number); attached hereto. Grantor has no trade names other than as listed on Schedule VI (Location, Chief Executive Office, Type of Organization, Jurisdiction of
Organization and Organizational Identification Number) attached hereto. Within the five years preceding the Effective Date, Grantor has not changed its name, location of its
chief executive office, type of organization, jurisdiction of organization or organizational identification number from those set forth in Schedule VI  (Location,  Chief  Executive
Office, Type of Organization, Jurisdiction of Organization and Organizational Identification Number) attached hereto except as set forth in Schedule VII (Changes in Name,
Location, Etc.) attached hereto.

-10-

 
 
 
 
 
 
 
 
 
 
 
(b)          Grantor is the legal and beneficial owner of the Collateral granted or purported to be granted by it free and clear of any Lien, claim, option or
right of others, except for the security interest created under this Agreement or permitted hereunder and listed on Schedule X (Permitted Liens). No effective financing statement or
other instrument similar in effect covering all or any part of such Collateral or listing Grantor or any trade name of Grantor as debtor is on file in any recording office, except such as
may have been filed in favor of the Collateral Agent relating to the Transaction Documents or as otherwise permitted under the Securities Purchase Agreement.

(c)          All of the Equipment and Inventory of Grantor is located at the places specified therefor in Schedule VIII (Locations of Equipment, Inventory
and Books and Records) attached hereto or at another location as to which Grantor has complied with the requirements of Section 13(a). Grantor has exclusive possession and
control of its Equipment and Inventory.

(d)          All books and records related to the Collateral are located at the places specified therefor in Schedule VIII (Locations of Equipment, Inventory
and  Books  and  Records)  attached  hereto.  Grantor  agrees  to  obtain  a  lien  waiver  and  access  agreement  in  favor  of  the  Collateral Agent,  in  form  and  substance  reasonably
satisfactory to the Secured Parties, with respect to each location in which any books and records are stored. Grantor further agrees to deliver a fully-executed copy of such lien
waiver and access agreement to the Collateral Agent prior to the delivery of such books and records to any other location.

Collateral Agent.

(e)          None of the Receivables or Agreement Collateral is evidenced by a promissory note or other instrument that has not been delivered to the

(f)          If Grantor is an issuer of Security Collateral, Grantor confirms that it has received notice of the security interest granted hereunder.

(g)          The Pledged Equity pledged by Grantor hereunder (if any) has been duly authorized and validly issued and is fully paid and non-assessable.
The Pledged Debt issued by Grantor and pledged by another Grantor hereunder has been duly authorized, authenticated or issued and delivered, is the valid and legally binding
obligation of the issuers thereof and is evidenced by one or more promissory notes (which promissory notes have been delivered to the Collateral Agent).

(h)          The Pledged Equity pledged by Grantor constitutes the percentage of the issued and outstanding Equity Interests of the issuers thereof
indicated on Part I of Schedule I (Investment Property) attached hereto. The Pledged Debt constitutes all of the outstanding indebtedness owed to Grantor by the issuers thereof
and is outstanding in the principal amount indicated, Part II of Schedule I (Investment Property) attached hereto, as of the date hereof and is not in default.

Property).

(i)          Grantor has no investment property, other than the investment property listed on Schedule I (Pledged Equity; Pledged Debt; Investment

(j)          Grantor shall use best efforts to deliver to the Collateral Agent a consent in form and substance reasonably satisfactory to the Secured Parties
from each party to the Assigned Agreements to which the Borrower is a party to the grant of a security interest in such Assigned Agreement pursuant to this Agreement (which
by its terms does not require any such consent or for which a consent was previously obtained).

-11-

 
 
 
 
 
 
 
 
 
 
 
 
 
Accounts and additional deposit accounts as to which Grantor has complied (or as the case may be, will comply) with the applicable requirements of Section 10.

(k)                    Grantor  has  no  deposit  accounts  other  than  the  Deposit Accounts  listed  on Schedule  II  (Deposit  Accounts)  attached  hereto,  Excluded

attached hereto and additional letters of credit as to which Grantor has complied with the requirements of Section 19.

(l)          Grantor is not a beneficiary or assignee under any letter of credit, other than the letters of credit described in Schedule IX (Letters of Credit)

(m)          This Agreement creates in favor of the Collateral Agent for the benefit of the Secured Parties a valid first priority security interest in the
Collateral granted by Grantor, securing the payment of the Secured Obligations; such security interest is subject in priority only to the Permitted Liens and the recording of all
filings and other actions (including, without limitation, (A) actions necessary to obtain control of Collateral as provided in Sections 9-104, 9-105, 9-106 and 9-107 of the UCC and (B)
actions necessary to perfect the Collateral Agent’s security interest with respect to Collateral evidenced by a certificate of title) necessary to perfect the security interest in the
Collateral granted by Grantor have been duly made or taken and are in full force and effect on and after the date hereof.

(n)          No authorization or approval or other action by, and no notice to or filing with, any governmental authority or regulatory body or any other
third party is required for (i) the grant by Grantor of the security interest granted hereunder or for the execution, delivery or performance of this Agreement by Grantor, (ii) the
perfection or maintenance of the security interest created hereunder (including the first priority nature of such security interest), except for the filing of financing and continuation
statements under the UCC, which financing statements shall have been duly filed within 45 days of the Closing, as defined in the Securities Purchase Agreement and, upon filing,
shall be in full force and effect, the recordation of the Intellectual Property Security Agreements referred to in Section 17(c) with the U.S. Patent and Trademark Office and the U.S.
Copyright Office, and the actions described in Section 9 with respect to the Security Collateral, which actions have been taken and are in full force and effect, or (iii) the exercise by
the Collateral Agent of its voting or other rights provided for in this Agreement or the remedies in respect of the Collateral pursuant to this Agreement, except as may be required in
connection with the disposition of any portion of the Security Collateral by laws affecting the offering and sale of securities generally.

(o)          The Inventory that has been produced or distributed by Grantor has been produced in material compliance with all requirements of applicable

law.

(p)          As to itself and its Intellectual Property Collateral:

(i)          The operation of Grantor’s business as currently conducted or as contemplated to be conducted and the use of the Intellectual
Property Collateral in connection therewith, to the best of Grantor’s knowledge, do not conflict with, infringe, misappropriate, dilute, misuse or otherwise violate the intellectual
property rights of any third party.

-12-

 
 
 
 
 
 
 
 
 
 
 
Intellectual Property Collateral subject only to the terms of the IP Agreements.

(ii)         Grantor is the exclusive owner of all right, title and interest in and to the Intellectual Property Collateral, and is entitled to use all

(iii)        Subject to Schedule XI (Excluded Assets), the Intellectual Property Collateral set forth on Schedule IV (Intellectual Property) attached
hereto includes all of the patents, patent applications, domain names, trademark registrations and applications, copyright registrations and applications and IP Agreements owned
by Grantor as of the date hereof.

(iv)        The Intellectual Property Collateral is subsisting and has not been adjudged invalid or unenforceable in whole or in part, and to the
best of Grantor’s knowledge, is valid and enforceable. Grantor is not aware of any uses of any item of Intellectual Property Collateral that could be expected to lead to such item
becoming invalid or unenforceable.

any of the Intellectual Property Collateral.

(v)         The consummation of the transactions contemplated by the Transaction Documents will not result in the termination or impairment of

commercial tort claims as to which Grantor has complied with the requirements of Section 20.

(q)                    Grantor  has  no  commercial  tort  claims  other  than  those  listed  in Schedule  V  (Commercial  Tort  Claims)  attached  hereto  and  additional

Section 12.           Further Assurances.

(a)          Grantor agrees that from time to time, at the expense of Grantor, Grantor will promptly execute and deliver, or otherwise authenticate, all further
instruments and documents, and take all further action that may be necessary or desirable, or that the Collateral Agent may request, in order to perfect and protect any pledge or
security interest granted or purported to be granted by Grantor hereunder or to enable the Collateral Agent to exercise and enforce its rights and remedies hereunder with respect
to any Collateral of Grantor. Without limiting the generality of the foregoing, Grantor will promptly with respect to Collateral of Grantor: (i) mark conspicuously each document
included in Inventory, each chattel paper included in Receivables, each Related Contract and, at the request of the Collateral Agent, each of its records pertaining to such Collateral
with a legend, in form and substance reasonably satisfactory to the  Secured  Parties, indicating that such document, chattel paper,  Related  Contract, Assigned Agreement or
Collateral is subject to the security interest granted hereby; (ii) if any such Collateral shall be evidenced by a certificate, promissory note or other instrument or chattel paper,
deliver and pledge to the Collateral Agent hereunder such certificate, note or instrument or chattel paper duly indorsed and accompanied by duly executed instruments of transfer
or assignment, all in form and substance reasonably satisfactory to the Secured Parties; (iii) file such financing or continuation statements, or amendments thereto, and such other
instruments or notices, as may be necessary or desirable, or as the Collateral Agent may request, in order to perfect and preserve the security interest granted or purported to be
granted by Grantor hereunder; (iv) take all action to ensure that the Collateral Agent’s security interest is noted on any certificate of title related to any Collateral evidenced by a
certificate  of  title;  (v)  to  cause  the  relevant  depository  institutions,  banks,  financial  intermediaries,  securities  intermediaries  and  issuers  to  execute  and  deliver  such  Deposit
Account Control Agreements, Uncertificated Security Control Agreements, Securities Account Control Agreements and other control agreements, as may be necessary or as the
Collateral Agent may from time to time require; and (vi) deliver to the Collateral Agent evidence that all other actions that the Collateral Agent may deem reasonably necessary or
desirable in order to perfect and protect the security interest granted or purported to be granted by Grantor under this Agreement has been taken.

-13-

 
 
 
 
 
 
 
 
 
 
 
(b)          Grantor hereby authorizes the Secured Parties to file one or more financing or continuation statements, and amendments thereto, including,
without limitation, one or more financing statements indicating that such financing statements cover all assets or all personal property (or words of similar effect) of Grantor,
regardless of whether any particular asset described in such financing statements falls within the scope of the UCC or the granting clause of this Agreement. A photocopy or other
reproduction of this Agreement shall be sufficient as a financing statement where permitted by law. Grantor ratifies its authorization for the Secured Parties to have filed such
financing statements, continuation statements or amendments filed prior to the date hereof.

Grantor and such other reports in connection with such Collateral as the Secured Parties may reasonably request, all in reasonable detail.

(c)          Grantor will furnish to the Collateral Agent from time to time statements and schedules further identifying and describing the Collateral of

Section 13.          As to Equipment and Inventory.

(a)          Grantor will keep its Equipment and Inventory (other than Inventory sold in the ordinary course of business and Equipment and Inventory in
transit in the ordinary course of business) at the places therefor specified in Section 11(c) or, upon ten (10) Business Days’ prior written notice to the Collateral Agent, at such
other places designated by Grantor in such notice which shall be an approved warehouse as to which a lien waiver and access agreement has been obtained in favor of and
delivered to the Collateral Agent, in form and substance reasonably satisfactory to the Secured Parties.

(b)          Grantor will cause its Equipment to be maintained and preserved in the same condition, repair and working order as when new, ordinary wear
and tear excepted, and will forthwith, or in the case of any loss or damage to any of such Equipment as soon as practicable after the occurrence thereof, make or cause to be made
all repairs, replacements and other improvements in connection therewith that are desirable to such end.

(c)          Grantor will pay promptly when due all property and other taxes, assessments and governmental charges or levies imposed upon, and all claims
(including, without limitation, claims for labor, materials and supplies) against, its Equipment and Inventory. In producing its Inventory, Grantor will comply, in all material respects,
with all requirements of applicable law.

-14-

 
 
 
 
 
 
 
 
 
 
Section 14.           As to Books and Records.

Grantor will keep its books and records at the places therefor specified in Section 11(d) or, upon ten (10) Business Days’ prior written notice to the Collateral Agent, at
such other places designated by Grantor in such notice which shall be an approved warehouse as to which a lien waiver and access agreement has been obtained in favor of and
delivered to the Collateral Agent, in form and substance reasonably satisfactory to the Secured Parties.

Section 15.           Insurance.

Grantor  shall  maintain  insurance  (including  property  insurance,  lender  loss  payable  endorsements,  etc.)  in  such  amounts  and  covering  such  risks  as  are  reasonably
acceptable to the to the Secured Parties and are usually carried by companies engaged in similar businesses and owning similar properties in the same general areas in which
Grantor operates, including without limitation, insurance on the Collateral.

Section 16.           Post-Closing Changes; Collections on Assigned Agreements, Receivables and Related Contracts.

(a)          Grantor shall not change its name, type of organization, jurisdiction of organization, organizational identification number or location from those
set  forth  in Section 11(a) of this Agreement without prior written notice to the Collateral Agent. Grantor will hold and preserve its records relating to the Collateral, including,
without limitation, the Assigned Agreements and Related Contracts, and will permit representatives of the Collateral Agent at any time during normal business hours and upon
reasonable notice to inspect and make abstracts from such records and other documents. If any Grantor does not have an organizational identification number and later obtains
one, it will forthwith notify the Collateral Agent of such organizational identification number.

(b)          Except as otherwise provided in this Section 16, Grantor will continue to collect, at its own expense, all amounts due or to become due to
Grantor under the Assigned Agreements, Receivables and Related Contracts. In connection with such collections, Grantor may take such action as Grantor may deem necessary or
advisable to enforce collection of the Assigned Agreements, Receivables and Related Contracts;  provided, however, that the Collateral Agent shall have the right at any time,
upon the occurrence and during the continuance of an Event of Default, to take any steps it or the other Secured Parties may deem necessary or advisable, including but not
limited to, notifying the obligors under any Assigned Agreements, Receivables and Related Contracts of the assignment of such Assigned Agreements, Receivables and Related
Contracts to the Collateral Agent and directing such obligors to make payment of all amounts due or to become due to Grantor thereunder directly to the Collateral Agent and,
upon such notification and at the expense of Grantor, to enforce collection of any such Assigned Agreements, Receivables and Related Contracts, to adjust, settle or compromise
the amount or payment thereof, in the same manner and to the same extent as  Grantor might have done, and to otherwise exercise all rights  with  respect  to  such Assigned
Agreements, Receivables and Related Contracts, including, without limitation, those set forth set forth in Section 9-607 of the UCC. After receipt by any Grantor of the notice from
the Collateral Agent referred to in the proviso to the preceding sentence, Grantor will not adjust, settle or compromise the amount or payment of any Receivable or amount due on
any Assigned Agreement or  Related  Contract, release wholly or partly any obligor thereof or allow any credit or discount thereon.  No  Grantor will permit or consent to the
subordination of its right to payment under any of the Assigned Agreements, Receivables and Related Contracts to any other indebtedness or Obligations of the obligor thereof.

-15-

 
 
 
 
 
 
 
 
 
 
 
Section 17.           As to Intellectual Property Collateral.

(a)          No Grantor shall, without the written consent of the Collateral Agent, discontinue use of or otherwise abandon any Intellectual Property
Collateral,  or  abandon  any  right  to  file  an  application  for  patent,  trademark,  or  copyright,  unless  Grantor  shall  have  previously  determined  that  such  use  or  the  pursuit  or
maintenance of such Intellectual Property Collateral is no longer desirable in the conduct of Grantor’s business and that the loss thereof could not reasonably be expected to have
a Material Adverse Change.

(b)          Grantor shall use proper statutory notice in connection with its use of each item of its Intellectual Property Collateral. Except as permitted in
Section 17(a) above, Grantor shall not do or permit any act or knowingly omit to do any act whereby any of its Intellectual Property Collateral may lapse or become invalid or
unenforceable or placed in the public domain.

(c)          With respect to its Intellectual Property Collateral, Grantor agrees to execute or otherwise authenticate an agreement, in substantially the form
set forth in Exhibit A hereto or otherwise in form and substance reasonably satisfactory to the Secured Parties (an “Intellectual Property Security Agreement”), for recording the
security interest granted hereunder to the Collateral Agent in such Intellectual Property Collateral with the U.S. Patent and Trademark Office, the U.S. Copyright Office and any
other governmental authorities necessary to perfect the security interest hereunder in such Intellectual Property Collateral.

(d)          Grantor agrees that should it obtain an ownership interest in any item of the type set forth in Section 6(g) that is not on the date hereof a part of
the Intellectual Property Collateral (“After-Acquired Intellectual Property”) (i) the provisions of this Agreement shall automatically apply thereto, and (ii) any such After-Acquired
Intellectual Property and, in the case of trademarks, the goodwill symbolized thereby, shall automatically become part of the Intellectual Property Collateral subject to the terms and
conditions of this Agreement with respect thereto. Grantor shall give prompt written notice to the Collateral Agent identifying the After-Acquired Intellectual Property, and Grantor
shall execute and deliver to the Collateral Agent with such written notice, or otherwise authenticate, an agreement substantially in the form of Exhibit B hereto or otherwise in form
and substance reasonably satisfactory to the Secured Parties (an “IP Security Agreement Supplement”) covering such After-Acquired Intellectual Property, which IP Security
Agreement Supplement shall be recorded with the U.S. Patent and Trademark Office, the U.S. Copyright Office and any other governmental authorities necessary to perfect the
security interest hereunder in such After-Acquired Intellectual Property.

-16-

 
 
 
 
 
 
 
 
 
Section 18.         Voting Rights; Dividends; Etc. (a) So long as no Event of Default shall have occurred and be continuing:

(i)          Grantor shall be entitled to exercise any and all voting and other consensual rights pertaining to the Security Collateral of Grantor or
any part thereof for any purpose; provided, however, that Grantor will not exercise or refrain from exercising any such right if such action would reasonably be expected to have a
material adverse effect on the value of the Security Collateral or any part thereof.

(ii)         Grantor shall be entitled to receive and retain any and all dividends, interest and other distributions paid in respect of the Security
Collateral of Grantor if and to the extent that the payment thereof is not otherwise prohibited by the terms of the Transaction Documents; provided, however, except as otherwise
provided in the Securities Purchase Agreement, any and all dividends, interest and other distributions paid or payable other than in cash in respect of, and instruments and other
property received, receivable or otherwise distributed in respect of, or in exchange for, any Security Collateral shall be, and shall be forthwith delivered to the Collateral Agent to
hold as, Security Collateral and shall, if received by Grantor, be received in trust for the benefit of the Collateral Agent, be segregated from the other property or funds of Grantor
and be forthwith delivered to the Collateral Agent as Security Collateral in the same form as so received (with any necessary endorsement).

(iii)        The Collateral Agent will execute and deliver (or cause to be executed and delivered) to Grantor all such proxies and other instruments
as Grantor may reasonably request for the purpose of enabling Grantor to exercise the voting and other rights that it is entitled to exercise pursuant to paragraph (i) above and to
receive the dividends or interest payments that it is authorized to receive and retain pursuant to paragraph (ii) above.

(b)          Upon the occurrence and during the continuance of an Event of Default:

(i)          All rights of Grantor (x) to exercise or refrain from exercising the voting and other consensual rights that it would otherwise be entitled
to exercise pursuant to Section 18(a)(i) shall, upon notice to Grantor by the Collateral Agent, cease and (y) to receive the dividends, interest and other distributions that it would
otherwise be authorized to receive and retain pursuant to Section 18(a)(ii) shall automatically cease, and all such rights shall thereupon become vested in the Collateral Agent,
which shall thereupon have the sole right to exercise or refrain from exercising such voting and other consensual rights and to receive and hold as  Security  Collateral such
dividends, interest and other distributions.

(ii)         All dividends, interest and other distributions that are received by any Grantor contrary to the provisions of paragraph (i) of this
Section 18(b) shall be received in trust for the benefit of the Collateral Agent, shall be segregated from other funds of Grantor and shall be forthwith paid over to the Collateral
Agent as Security Collateral in the same form as so received (with any necessary endorsement).

-17-

 
 
 
 
 
 
 
 
 
 
 
Section 19.           As to Letter-of-Credit Rights.

(a)          Grantor, by granting a security interest in its Receivables consisting of letter-of-credit rights to the Collateral Agent, intends to (and hereby
does) assign to the Collateral Agent its rights (including its contingent rights) to the proceeds of all Related Contracts consisting of letters of credit of which it is or hereafter
becomes a beneficiary or assignee. Grantor will promptly use commercially reasonable efforts to cause the issuer of each letter of credit in favor of Grantor and each nominated
person (if any) with respect thereto to consent to such assignment of the proceeds thereof pursuant to a consent in form and substance reasonably satisfactory to the Secured
Parties and deliver written evidence of such consent to the Collateral Agent.

(b)          Upon the occurrence of an Event of Default, Grantor will, promptly upon request by the Collateral Agent, (i) notify (and Grantor hereby
authorizes the Collateral Agent to notify) the issuer and each nominated person with respect to each of the Related Contracts consisting of letters of credit that the proceeds
thereof have been assigned to the Collateral Agent hereunder and any payments due or to become due in respect thereof are to be made directly to the Collateral Agent or its
designee and (ii) arrange for the Collateral Agent to become the transferee beneficiary of letter of credit.

Section  20.           Commercial Tort Claims. Grantor will promptly give notice to the Collateral Agent of any commercial tort claim that may arise after the date
hereof and will immediately execute or otherwise authenticate a supplement to this Agreement, and otherwise take all necessary action, to subject such commercial tort claim to the
first priority security interest created under this Agreement.

Section 21.            Transfers and Other Liens; Additional Shares.

(a)          Grantor agrees that it will not (i) sell, assign or otherwise dispose of, or grant any option with respect to, any of the Collateral, other than sales,
assignments and other dispositions of Collateral, and options relating to Collateral, permitted under the terms of the Securities Purchase Agreement, or (ii) create or suffer to exist
any Lien upon or with respect to any of the Collateral of Grantor except for the pledge, assignment and security interest created under this Agreement and Liens permitted under
the Securities Purchase Agreement.

(b)          Grantor agrees that it will (i) cause each issuer of the Pledged Equity pledged by Grantor not to issue any Equity Interests or other securities in
addition to or in substitution for the Pledged Equity issued by such issuer, except to Grantor, and (ii) pledge hereunder, immediately upon its acquisition (directly or indirectly)
thereof, any and all additional Equity Interests or other securities.

Section 22.            Collateral Agent Appointed Attorney in Fact. Grantor hereby irrevocably appoints the Collateral Agent as attorney in fact, with full authority in
the place and stead of Grantor and in the name of Grantor or otherwise, from time to time, to take any action and to execute any instrument that the Collateral Agent or the other
Secured Parties may deem necessary or advisable to accomplish the purposes of this Agreement, including, without limitation, upon the occurrence and during the continuance of
an Event of Default, to:

(a)          obtain and adjust insurance required to be paid to the Collateral Agent pursuant to, or in accordance with, Section 14,

-18-

 
 
 
 
 
 
 
 
 
 
 
 
 
respect of any of the Collateral,

(b)          ask for, demand, collect, sue for, recover, compromise, receive and give acquittance and receipts for moneys due and to become due under or in

(c)          receive, indorse and collect any drafts or other instruments, documents and chattel paper, in connection with clause (a) or (b) above, and

(d)          file any claims or take any action or institute any proceedings that the Collateral Agent or the other Secured Parties may deem necessary or
desirable for the collection of any of the Collateral or otherwise to enforce compliance with the terms and conditions of any Assigned Agreement or the rights of the Collateral
Agent with respect to any of the Collateral.

23.           Collateral Agent May Perform. If any Grantor fails to perform any agreement contained herein, the Collateral Agent may, but without any
obligation to do so and without notice, itself perform, or cause performance of, such agreement, and the expenses of the Collateral Agent incurred in connection therewith shall be
payable by Grantor under Section 26.

Section 

Section 24.           The Collateral Agent’s Duties.

(a)          The powers conferred on the Collateral Agent hereunder are solely to protect the Secured Parties’ interest in the Collateral and shall not impose
any duty upon it to exercise any such powers. Except for the safe custody of any Collateral in its possession and the accounting for moneys actually received by it hereunder, the
Collateral Agent shall have no duty as to any Collateral, as to ascertaining or taking action with respect to calls, conversions, exchanges, maturities, tenders or other matters
relative to any Collateral, whether or not any Secured Party has or is deemed to have knowledge of such matters, or as to the taking of any necessary steps to preserve rights
against any parties or any other rights pertaining to any Collateral. The Collateral Agent shall be deemed to have exercised reasonable care in the custody and preservation of any
Collateral in its possession if such Collateral is accorded treatment substantially equal to that which it accords its own property.

(b)          Anything contained herein to the contrary notwithstanding, the Collateral Agent may from time to time, when the Collateral Agent in its
discretion deems it to be necessary or advisable, appoint one or more subagents (each a “Subagent”) for the Collateral Agent hereunder with respect to all or any part of the
Collateral. In the event that the Collateral Agent so appoints any Subagent with respect to any Collateral, (i) the assignment and pledge of such Collateral and the security interest
granted in such Collateral by Grantor hereunder shall be deemed for purposes of this Security Agreement to have been made to such Subagent, in addition to the Collateral Agent,
for the ratable benefit of the Secured Parties, as security for the Secured Obligations of Grantor, (ii) such Subagent shall automatically be vested, in addition to the Collateral Agent,
with all rights, powers, privileges, interests and remedies of the Collateral Agent hereunder with respect to such Collateral, and (iii) the term “Collateral Agent,” when used herein in
relation to any rights, powers, privileges, interests and remedies of the Collateral Agent with respect to such Collateral, shall include such Subagent; provided, however, that no
such Subagent shall be authorized to take any action with respect to any such Collateral unless and except to the extent expressly authorized in writing by the Collateral Agent.

-19-

 
 
 
 
 
 
 
 
 
 
 
Section 25.            Remedies. If any Event of Default shall have occurred and be continuing:

(a)          The Collateral Agent may exercise in respect of the Collateral, in addition to other rights and remedies provided for herein or otherwise available
to it, all the rights and remedies of a secured party upon default under the UCC (whether or not the UCC applies to the affected Collateral) and also may: (i) require Grantor to, and
Grantor hereby agrees that it will at its expense and upon request of the Collateral Agent forthwith, to the extent commercially feasible, assemble all or part of the Collateral as
directed by the Collateral Agent and make it available to the Collateral Agent at a place and time to be designated by the Collateral Agent that is reasonably convenient to both
parties; (ii) without notice except as specified below or as otherwise required pursuant to Section 9-611 of the UCC, sell the Collateral or any part thereof in one or more parcels at
public or private sale, at any of the Collateral Agent’s offices or elsewhere, for cash, on credit or for future delivery, and upon such other terms as are in accordance with applicable
law; (iii) occupy any premises owned or leased by any of the Grantors where the Collateral or any part thereof is assembled or located for a reasonable period in order to effectuate
its rights and remedies hereunder or under law; and (iv) exercise any and all rights and remedies of any of the Grantors under or in connection with the Collateral, or otherwise in
respect of the Collateral, including, without limitation, (A) any and all rights of Grantor to demand or otherwise require payment of any amount under, or performance of any
provision of, the Assigned Agreements, the Receivables, the Related Contracts and the other Collateral, (B) withdraw, or cause or direct the withdrawal, of all funds with respect to
the Account Collateral and (C) exercise all other rights and remedies with respect to the Assigned Agreements, the Receivables, the Related Contracts and the other Collateral,
including, without limitation, those set forth in Section 9-607 of the UCC. Grantor agrees that, to the extent notice of sale shall be required by law, at least ten (10) days’ notice to
Grantor of the time and place of any public sale or the time after which any private sale is to be made shall constitute reasonable notification. The Collateral Agent shall not be
obligated  to  make  any  sale  of  Collateral  regardless  of  notice  of  sale  having  been  given.  The  Collateral Agent  may  adjourn  any  public  or  private  sale  from  time  to  time  by
announcement at the time and place fixed therefor, and such sale may, without further notice (except as otherwise required by Section 9-611 of the UCC), be made at the time and
place to which it was so adjourned.

(b)          Any cash held by or on behalf of the Collateral Agent and all cash proceeds received by or on behalf of the Collateral Agent in respect of any
sale of, collection from, or other realization upon all or any part of the Collateral may, in the discretion of the Collateral Agent, be held by the Collateral Agent as collateral for the
benefit of the Secured Parties against, all or any part of the Secured Obligations. Any surplus of such cash or cash proceeds held by or on the behalf of the Collateral Agent and
remaining after payment in full of all the Secured Obligations shall be paid over to Grantor or to whomsoever may be lawfully entitled to receive such surplus.

(c)          All payments received by any Grantor under or in connection with any Assigned Agreement or otherwise in respect of the Collateral shall be
received in trust for the benefit of the Collateral Agent, shall be segregated from other funds of Grantor and shall be forthwith paid over to the Collateral Agent in the same form as
so received (with any necessary endorsement).

-20-

 
 
 
 
 
 
 
 
(d)          [RESERVED].

(e)          In the event of any sale or other disposition of any of the Intellectual Property Collateral of Grantor, the goodwill symbolized by any Trademarks
subject  to  such  sale  or  other  disposition  shall  be  included  therein,  and  Grantor  shall  supply  to  the  Collateral Agent  or  its  designee  Grantor’s  know-how  and  expertise,  and
documents and things relating to any Intellectual Property Collateral subject to such sale or other disposition, and Grantor’s customer lists and other records and documents
relating to such Intellectual Property Collateral and to the manufacture, distribution, advertising and sale of products and services of Grantor.

that, upon request of the Collateral Agent, Grantor will, at its own expense:

(f)          If the Collateral Agent shall exercise its right to sell all or any of the Security Collateral of any Grantor pursuant to this Section 25, Grantor agrees

(i)          execute and deliver, and cause each issuer of such Security Collateral contemplated to be sold and the directors and officers thereof to
execute and deliver, all such instruments and documents, and do or cause to be done all such other acts and things, as may be necessary or, in the opinion of the Collateral Agent,
advisable to register such Security Collateral under the provisions of the Securities Act of 1933 (as amended from time to time, the “Securities Act”), to cause the registration
statement relating thereto to become effective and to remain effective for such period as prospectuses are required by law to be furnished and to make all amendments and
supplements thereto and to the related prospectus that, in the opinion of the Collateral Agent or the other Secured Parties, are necessary or advisable, all in conformity with the
requirements of the Securities Act and the rules and regulations of the Securities and Exchange Commission applicable thereto;

governmental approvals for the sale of such Security Collateral, as requested by the Collateral Agent;

(ii)                  use  its  best  efforts  to  qualify  the  Security  Collateral  under  the  state  securities  or  “Blue  Sky”  laws  and  to  obtain  all  necessary

statement that will satisfy the provisions of Section 16(a) of the Securities Act;

(iii)        cause each such issuer of such  Security  Collateral to make available to its security holders, as soon as practicable, an earnings

or the other Secured Parties, advisable to enable the Collateral Agent to effect the sale of such Security Collateral upon such terms as are in accordance with applicable law; and

(iv)        provide the Collateral Agent with such other information and projections as may be necessary or, in the opinion of the Collateral Agent

thereof valid and binding and in compliance with applicable law.

(v)         do or cause to be done all such other acts and things as may be necessary to make such sale of such Security Collateral or any part

(g)          The Collateral Agent is authorized, in connection with any sale of the Security Collateral pursuant to this Section 25, to deliver or otherwise
disclose to any prospective purchaser of the Security Collateral: (i) any registration statement or prospectus, and all supplements and amendments thereto, prepared pursuant to
subsection (f)(i) above; (ii) any information and projections provided to it pursuant to subsection (f)(iv) above; and (iii) any other information in its possession relating to such
Security Collateral.

-21-

 
 
 
 
 
 
 
 
 
 
 
 
 
(h)          Grantor acknowledges the impossibility of ascertaining the amount of damages that would be suffered by the Secured Parties by reason of the
failure by Grantor to perform any of the covenants contained in subsection (f) above and, consequently, agrees that, if Grantor shall fail to perform any of such covenants, it will
pay,  as  liquidated  damages  and  not  as  a  penalty,  an  amount  equal  to  the  value  of  the  Security  Collateral  on  the  date  the  Collateral Agent  shall  demand  compliance  with
subsection (f) above.

Section 26.            Indemnity and Expenses.

(a)          Grantor agrees to indemnify, defend and save and hold harmless each Secured Party and each of their Affiliates and their Related Parties (each,
an “Indemnified Party”) from and against, and shall pay on demand, any and all claims, damages, losses, liabilities and expenses (including, without limitation, reasonable fees and
expenses of counsel) that may be incurred by or asserted or awarded against any  Indemnified  Party, in each case arising out of or in connection with or resulting from this
Agreement (including, without limitation, enforcement of this Agreement); provided that such indemnity shall not, as to any Indemnified Party, be available to the extent that such
losses, claims, damages, liabilities or related expenses (x) are determined by a court of competent jurisdiction by final and nonappealable judgment to have resulted from the bad
faith, gross negligence or willful misconduct of such Indemnified Party or any of its officers, directors or employees, or (y) arising from disputes solely among the Collateral Agent,
the  Buyers  and/or  their  transferees  (other  than  in  respect  of  disputes  against  an  Indemnitee  in  its  capacity  as  Collateral Agent  or  any  similar  role  under  the  Transaction
Documents).

(b)          Without limiting the foregoing clause (a), Grantor will upon demand pay to the Collateral Agent the amount of any and all (1) reasonable
expenses, including, without limitation, the reasonable fees and expenses of its counsel and of any experts and agents, that the Collateral Agent may incur in connection with
(i) the administration of this Agreement, and (ii) the custody, preservation, use or operation of, or the sale of, collection from or other realization upon, any of the Collateral of
Grantor, and (2) expenses, including, without limitation, the fees and expenses of its counsel and of any experts and agents, that the Collateral Agent may incur in connection with
(i) the exercise or enforcement of any of the rights of the Collateral Agent or the other Secured Parties hereunder or (ii) the failure by Grantor to perform or observe any of the
provisions hereof.

-22-

 
 
 
 
 
 
 
 
Section 

27.           Amendments; Waivers; Additional Grantors; Etc.   No amendment or waiver of any provision of this Agreement, and no consent to any
departure by any Grantor herefrom, shall in any event be effective unless the same shall be in writing and signed by the Collateral Agent, and then such waiver or consent shall be
effective only in the specific instance and for the specific purpose for which given. No failure on the part of the Collateral Agent to exercise, and no delay in exercising any right
hereunder, shall operate as a waiver thereof; nor shall any single or partial exercise of any such right preclude any other or further exercise thereof or the exercise of any other right.

Section 

28.           Notices, Etc.  Except  as  otherwise  provided  herein,  whenever  it  is  provided  herein  that  any  notice,  demand,  request,  consent,  approval,
declaration or other communication shall or may be given to or served upon any of the parties by any other party, or whenever any of the parties desires to give and serve upon
any other party any communication with respect to this Agreement, each such notice, demand, request, consent, approval, declaration or other communication shall be in writing
and shall be given in the manner and to the address, and deemed received, as provided for in accordance with the terms of the Collateral Agency Agreement. Delivery by email or
facsimile of an executed counterpart of any amendment, supplement or waiver of any provision of this Agreement or any Schedule or Exhibit relating thereto shall be effective as
delivery of an original executed counterpart thereof.

Section  29.           Continuing Security Interest. This Agreement shall create a continuing security interest in the Collateral and shall (a) remain in full force and
effect until the indefeasible payment in full in cash of the Secured Obligations, (b) be binding upon Grantor, its successors and assigns and (c) inure, together with the rights and
remedies of the Collateral Agent hereunder, to the benefit of the Secured Parties and their respective successors, transferees and assigns.

Section 30.           Release; Termination.

(a)          Upon any sale, lease, transfer or other disposition of any item of Collateral of Grantor (other than sales of Inventory in the ordinary course of
business) in accordance with the terms of the Transaction Documents, the Collateral Agent will, at Grantor’s expense, execute and deliver to Grantor such documents as Grantor
shall reasonably request to evidence the release of such item(s) of Collateral from the assignment and security interest granted hereby; provided, however, that (i) at the time of
such request and such release no Event of Default shall have occurred and be continuing, (ii) Grantor shall have delivered to the Collateral Agent, at least ten (10) Business Days
prior to the date of the proposed release, a written request for release describing the item of Collateral and the terms of the sale, lease, transfer or other disposition in reasonable
detail,  including,  without  limitation,  the  price  thereof  and  any  expenses  in  connection  therewith,  together  with  a  form  of  release  for  execution  by  the  Collateral Agent  and  a
certificate of Grantor to the effect that the transaction is in compliance with the Transaction Documents and as to such other matters as the Collateral Agent may request, (iii) the
proceeds of any such sale, lease, transfer or other disposition required to be applied, or any payment to be made in connection therewith, shall, to the extent so required, be paid or
made to, or in accordance with the instructions of, the Collateral Agent, and (iv) the Collateral Agent shall have received written direction from the Buyers in accordance with the
Collateral Agency Agreement.

-23-

 
 
 
 
 
 
 
 
 
(b)          Upon the indefeasible payment in full in cash of the Secured Obligations, other than any unasserted contingent Obligations, the guaranty,
pledge and security interest granted hereby shall terminate and all rights to the  Collateral shall revert to  Grantor.  Upon any such termination, the  Secured  Parties will, at the
Grantor’s expense, execute and deliver to Grantor such documents as Grantor shall reasonably request to evidence such termination.

Section 31.          Execution in Counterparts. This Agreement may be executed in any number of counterparts, each of which when so executed shall be deemed to
be an original and all of which taken together shall constitute one and the same agreement. Delivery of an executed counterpart of a signature page to this Agreement by email or
facsimile shall be effective as delivery of an original executed counterpart of this Agreement.

Section 32.           Governing Law; Jurisdiction; Waiver of Jury Trial, Etc.

( a )          GOVERNING LAW. THIS AGREEMENT AND ANY CLAIMS, CONTROVERSY, DISPUTE OR CAUSE OF ACTION (WHETHER IN TORT OR
OTHERWISE) BASED ON, ARISING OUT OF OR RELATING TO THIS GUARANTY AND THE TRANSACTIONS CONTEMPLATED HEREBY SHALL BE GOVERNED BY, AND
CONSTRUED IN ACCORDANCE WITH, THE LAW OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS (OTHER THAN SECTIONS 5-1401 AND 5-
1402 OF THE NEW YORK GENERAL OBLIGATIONS LAWS).

(b)          SUBMISSION TO JURISDICTION. GRANTOR IRREVOCABLY AND UNCONDITIONALLY SUBMITS, FOR ITSELF AND ITS PROPERTY, TO
THE  NONEXCLUSIVE  JURISDICTION  OF  THE  COURTS  OF  THE  STATE  OF  NEW  YORK  SITTING  IN  NEW  YORK  COUNTY  OR  OF  THE  UNITED  STATES  FOR  THE
SOUTHERN DISTRICT OF SUCH STATE, AND ANY APPELLATE COURT FROM ANY THEREOF, IN ANY ACTION OR PROCEEDING ARISING OUT OF OR RELATING TO
THIS AGREEMENT, OR FOR RECOGNITION OR ENFORCEMENT OF ANY JUDGMENT, AND EACH OF THE PARTIES HERETO IRREVOCABLY AND UNCONDITIONALLY
AGREES THAT ALL CLAIMS IN RESPECT OF ANY SUCH ACTION OR PROCEEDING MAY BE HEARD AND DETERMINED IN SUCH NEW YORK COURT OR, TO THE
FULLEST EXTENT PERMITTED BY APPLICABLE LAW, IN SUCH FEDERAL COURT. EACH OF THE PARTIES HERETO AGREES THAT A FINAL JUDGMENT IN ANY SUCH
ACTION OR PROCEEDING SHALL BE CONCLUSIVE AND MAY BE ENFORCED IN OTHER JURISDICTIONS BY SUIT ON THE JUDGMENT OR IN ANY OTHER MANNER
PROVIDED  BY  LAW.  NOTHING  IN  THIS  AGREEMENT  SHALL  AFFECT  ANY  RIGHT  THAT  THE  COLLATERAL  AGENT  OR  ANY  OTHER  SECURED  PARTY  MAY
OTHERWISE HAVE TO BRING ANY ACTION OR PROCEEDING RELATING TO THIS AGREEMENT AGAINST ANY GRANTOR OR ITS PROPERTIES IN THE COURTS OF
ANY JURISDICTION.

-24-

 
 
 
 
 
 
 
 
 
( c )          WAIVER  OF  VENUE.  GRANTOR  IRREVOCABLY AND  UNCONDITIONALLY  WAIVES,  TO  THE  FULLEST  EXTENT  PERMITTED  BY
APPLICABLE LAW, ANY OBJECTION THAT IT MAY NOW OR HEREAFTER HAVE TO THE LAYING OF VENUE OF ANY ACTION OR PROCEEDING ARISING OUT OF OR
RELATING TO THIS AGREEMENT IN ANY COURT REFERRED TO IN PARAGRAPH (b) OF THIS SECTION. GRANTOR HEREBY IRREVOCABLY WAIVES, TO THE FULLEST
EXTENT PERMITTED BY APPLICABLE LAW, THE DEFENSE OF AN INCONVENIENT FORUM TO THE MAINTENANCE OF SUCH ACTION OR PROCEEDING IN ANY SUCH
COURT.

NOTICES IN SECTION 28.

( d )          SERVICE OF PROCESS. GRANTOR HERETO IRREVOCABLY CONSENTS TO SERVICE OF PROCESS IN THE MANNER PROVIDED FOR

(

e

)          WAIVER  OF  JURY  TRIAL.  GRANTOR  HERETO  HEREBY  IRREVOCABLY  WAIVES,  TO  THE  FULLEST  EXTENT  PERMITTED  BY

APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN ANY LEGAL PROCEEDING DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THIS
AGREEMENT  OR  THE  TRANSACTIONS  CONTEMPLATED  HEREBY  (WHETHER  BASED  ON  CONTRACT,  TORT  OR  ANY  OTHER  THEORY).  EACH  PARTY  HERETO
(A) CERTIFIES THAT NO REPRESENTATIVE, AGENT OR ATTORNEY OF ANY OTHER PERSON HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER
PERSON WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE FOREGOING WAIVER AND (B) ACKNOWLEDGES THAT IT AND THE OTHER PARTIES
HERETO HAVE BEEN INDUCED TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS IN THIS SECTION.

SIGNATURE PAGE FOLLOWS

-25-

 
 
 
 
 
 
 
 
written.

IN WITNESS WHEREOF, Grantor has caused this Agreement to be duly executed and delivered by its officer thereunto duly authorized as of the date first above

APDN (B.V.I.) INC.,
a corporation formed under the laws of the British Virgin Islands

By:
Name:
Title:

/s/ James A. Hayward
James A. Hayward
Authorized Signatory

SIGNATURES CONTINUE ON NEXT PAGE

Signature page to security agreement

 
 
 
 
 
 
 
 
 
 
 
 
 
ACCEPTED AND AGREED
as of the date first written above by:

DELAWARE TRUST COMPANY,
as Collateral Agent

By:
Name:
Title:

/s/ Alan R. Halpern
Alan R. Halpern
Vice President

Signature page to security agreement

 
 
 
 
 
 
 
 
 
 
Exhibit A to the
Security Agreement

FORM OF INTELLECTUAL PROPERTY SECURITY AGREEMENT

This INTELLECTUAL PROPERTY SECURITY AGREEMENT (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “IP Security Agreement”) dated __________, 20__, is made by APDN (B.V.I.) Inc., a corporation formed under the laws of the British Virgin Islands (the “ Grantor”), in
favor of DELAWARE TRUST COMPANY, a Delaware corporation, as collateral agent (the “ Collateral Agent”) for the Secured Parties (as defined in the Guaranty and Security
Agreement referred to below).

WHEREAS, Grantor is a wholly owned subsidiary of APPLIED DNA SCIENCES, a Delaware corporation (the “Company”) and the  Company is party to the
Securities Purchase Agreement dated as of August 31, 2018 (as amended, restated, amended and restated, supplemented or otherwise modified from time to time, the “ Securities
Purchase Agreement”) with the Buyers party thereto.

WHEREAS, pursuant to the Securities Purchase Agreement, the Grantor has executed and delivered that certain Guaranty and Security Agreement, dated as of
the date hereof, made by the  Grantor to the  Collateral Agent for the benefit of the  Secured  Parties (as amended, restated, amended and restated, supplemented or otherwise
modified from time to time, the “Security Agreement”; the capitalized terms defined therein and not otherwise defined herein being used herein as therein defined).

WHEREAS, under the terms of the Security Agreement, the Grantor has granted to the Collateral Agent, for the ratable benefit of the Secured Parties, a security
interest in, among other property, certain intellectual property of the Grantor, and have agreed as a condition thereof to execute this IP Security Agreement for recording with the
U.S. Patent and Trademark Office, the United States Copyright Office and other governmental authorities.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Grantor agrees as follows:

right, title and interest in and to the following (the “Collateral”):

SECTION 1. Grant of Security. Grantor hereby grants to the Collateral Agent for the ratable benefit of the Secured Parties a security interest in all of Grantor’s

(i)          all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all improvements

thereto, including, without limitation, those set forth in Schedule A hereto (the “Patents”);

(ii)         all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and other source
identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent that, and solely
during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under applicable federal
law), together, in each case, with the goodwill symbolized thereby, including, without limitation, those set forth in Schedule B hereto (the “Trademarks”);

 
 
 
 
 
 
 
 
 
 
 
 
 
(iii)        all copyrights, including, without limitation, copyrights in Computer Software (as hereinafter defined), internet web sites and the content thereof, whether
registered  or  unregistered,  including,  without  limitation,  the  copyright  registrations  and  applications  and  exclusive  copyright  licenses  set  forth  in Schedule  C  hereto  (the
“Copyrights”);

(iv)        all reissues, divisions, continuations, continuations-in-part, extensions, renewals and reexaminations of any of the foregoing, all rights in the foregoing
provided by international treaties or conventions, all rights corresponding thereto throughout the world and all other rights of any kind whatsoever of Grantor accruing thereunder
or pertaining thereto;

(v)         any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation, misuse or breach with

respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages; and

Obligations (as defined in the Security Agreement) relating to, any and all of the Collateral of or arising from any of the foregoing.

(vi)                any  and  all  proceeds  of,  collateral  for,  income,  royalties  and  other  payments  now  or  hereafter  due  and  payable  with  respect  to,  and  supporting

SECTION  2.          Security for Obligations. The grant of a security interest in the Collateral by Grantor under this IP Security Agreement secures the payment of
all Secured Obligations now or hereafter existing under or in respect of the Transaction Documents, whether direct or indirect, absolute or contingent, and whether for principal,
reimbursement obligations, interest, premiums, penalties, fees, indemnifications, contract causes of action, costs, expenses or otherwise. Without limiting the generality of the
foregoing, this IP Security Agreement secures, as to Grantor, the payment of all amounts that constitute part of the Secured Obligations and that would be owed by Grantor to any
Secured  Party  under  the  Transaction  Documents  but  for  the  fact  that  such  Secured  Obligations  are  unenforceable  or  not  allowable  due  to  the  existence  of  a  bankruptcy,
reorganization or similar proceeding involving Grantor.

Trademarks and any other applicable government officer record this IP Security Agreement.

SECTION 

3.          Recordation.  Grantor  authorizes  and  requests  that  the  Register  of  Copyrights,  the  Commissioner  for  Patents  and  the  Commissioner  for

be deemed to be an original and all of which taken together shall constitute one and the same agreement.

SECTION  4.          Execution in Counterparts. This IP Security Agreement may be executed in any number of counterparts, each of which when so executed shall

SECTION  5.          Grants, Rights and Remedies. This IP Security Agreement has been entered into in conjunction with the provisions of the Security Agreement.
Grantor does hereby acknowledge and confirm that the grant of the security interest hereunder to, and the rights and remedies of, the Collateral Agent with respect to the Collateral
are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated herein by reference as if fully set forth herein.

LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS.

SECTION  6.          GOVERNING LAW. THIS IP SECURITY AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE

[remainder of page intentionally blank]

-2-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, Grantor has caused this IP Security Agreement to be duly executed and delivered by its officer thereunto duly authorized as of the date

first above written.

APDN (B.V.I.) INC.,
a corporation formed under the laws of the British Virgin Islands

By:
Name:
Title:

Address for Notices:

 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Exhibit B to the
Security Agreement

FORM OF INTELLECTUAL PROPERTY SECURITY AGREEMENT SUPPLEMENT

This INTELLECTUAL PROPERTY SECURITY AGREEMENT SUPPLEMENT (as amended, restated, amended and restated, supplemented or otherwise modified
from time to time, the “IP Security Agreement Supplement”) dated __________, 20__, is made by APDN (B.V.I.) INC. a corporation formed under the laws of the British Virgin
Islands (the “Grantor”) in favor of DELAWARE TRUST COMPANY, a Delaware corporation, as collateral agent (the “ Collateral Agent”) for the Secured Parties (as defined in the
Guaranty and Security Agreement referred to below).

WHEREAS, Grantor is a wholly owned subsidiary of APPLIED DNA SCIENCES, a Delaware corporation (the “Company”) and the Company is party to the
Securities Purchase Agreement dated as of August 31, 2018 (as amended, restated, amended and restated, supplemented or otherwise modified from time to time, the “ Securities
Purchase Agreement”) with the Buyers party thereto.

WHEREAS, pursuant to the Securities Purchase Agreement, the Grantor has executed and delivered that certain Guaranty and Security Agreement, dated as
October 17, 2018, made by the Grantor to the Collateral Agent for the benefit of the Secured Parties (as amended, restated, amended and restated, supplemented or otherwise
modified from time to time, the “Security Agreement”) and that certain Intellectual Property Security Agreement dated [insert date of Intellectual Property Security Agreement]
made by the Grantor to the Collateral Agent for the benefit of the Secured Parties (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “IP Security Agreement”; the capitalized terms defined therein and not otherwise defined herein being used herein as therein defined).

WHEREAS, under the terms of the Security Agreement, the Grantor has granted to the Collateral Agent, for the ratable benefit of the Secured Parties, a security
interest in the Additional Collateral (as defined in Section 6 below) of the Grantor and has agreed as a condition thereof to execute this IP Security Agreement Supplement for
recording with the U.S. Patent and Trademark Office, the United States Copyright Office and other governmental authorities.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Grantor agrees as follows:

such Grantor’s right, title and interest in and to the following (the “Additional Collateral”):

SECTION  1.          Grant of Security. Each Grantor hereby grants to the Collateral Agent, for the ratable benefit of the Secured Parties, a security interest in all of

(i)          all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all improvements

thereto, including, without limitation, those set forth in Schedule A hereto (the “Patents”);

 
 
 
 
 
 
 
 
 
 
 
 
(ii)         all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and other source
identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent that, and solely
during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under applicable federal
law), together, in each case, with the goodwill symbolized thereby, including, without limitation, those set forth in Schedule B hereto (the “Trademarks”);

(ii)         all copyrights, including, without limitation, copyrights in Computer Software (as hereinafter defined), internet web sites and the content thereof, whether
registered  or  unregistered,  including,  without  limitation,  the  copyright  registrations  and  applications  and  exclusive  copyright  licenses  set  forth  in Schedule  C  hereto  (the
“Copyrights”);

(iii)        all reissues, divisions, continuations, continuations-in-part, extensions, renewals and reexaminations of any of the foregoing, all rights in the foregoing
provided by international treaties or conventions, all rights corresponding thereto throughout the world and all other rights of any kind whatsoever of such Grantor accruing
thereunder or pertaining thereto;

(iv)        all any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation, misuse or breach

with respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages; and

(v)                  any  and  all  proceeds  of,  collateral  for,  income,  royalties  and  other  payments  now  or  hereafter  due  and  payable  with  respect  to,  and  supporting

Obligations (as defined in the Security Agreement) relating to, any and all of the foregoing or arising from any of the foregoing.

2.          Security for Obligations.  The  grant  of  a  security  interest  in  the Additional  Collateral  by  the  Grantor  under  this  IP  Security Agreement
Supplement secures the payment of all Secured Obligations now or hereafter existing under or in respect of the Loan Documents, whether direct or indirect, absolute or contingent,
and whether for principal, reimbursement Obligations, interest, premiums, penalties, fees, indemnifications, contract causes of action, costs, expenses or otherwise.

SECTION 

Trademarks and any other applicable government officer to record this IP Security Agreement Supplement.

SECTION  3.          Recordation. The Grantor authorizes and requests that the Register of Copyrights, the Commissioner for Patents and the Commissioner for

SECTION  4.          Grants, Rights and Remedies. This IP Security Agreement Supplement has been entered into in conjunction with the provisions of the Security
Agreement. The Grantor does hereby acknowledge and confirm that the grant of the security interest hereunder to, and the rights and remedies of, the Collateral Agent with
respect to the Additional Collateral are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated herein by reference as if fully set forth
herein.

-2-

 
 
 
 
 
 
 
 
 
 
 
 
SECTION 5.          GOVERNING LAW. THIS IP SECURITY AGREEMENT SUPPLEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE

WITH, THE LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS.

authorized as of the date first above written.

IN  WITNESS  WHEREOF,  the  Grantor  has  caused  this  IP  Security Agreement  Supplement  to  be  duly  executed  and  delivered  by  its  officer  thereunto  duly

APDN (B.V.I.) INC.,
a corporation formed under the laws of the British Virgin Islands

By:
Name:
Title:

Address for Notices:

-3-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Part I: None.

Part II: None.

SCHEDULE I

Investment Property

 
 
 
 
 
 
 
None.

SCHEDULE II

Deposit Accounts

 
 
 
 
 
 
None.

SCHEDULE III

Assigned Agreements

 
 
 
 
 
 
SCHEDULE IV

Intellectual Property

Copyrights

None.

Trademarks

Application Date

Application No

Registration Date

10/27/2006

10/26/2006
8/16/2017
6/9/2017
12/20/2016
11/09/2009
10/09/2015
10/09/2015
07/19/2012
10/09/2015
10/09/2015
05/09/2011
04/16/2010
05/06/2011
12/07/2007
05/06/2011
08/12/2010
12/07/2007
05/06/2011
05/06/2011
05/06/2011
10/26/2006

1143760

1321773
1368527
16828287
16189961
1022396
1277705
1,280,146
011054285
1,277,538
1,282,810
009948258
009034349
00948258
006537047
009948092
1048621
006536999
009948118
009948308
009948423
005419031

09/29/2008

11/28/2012
8/7/2017
9-Jun-17
04/24/2017
11/09/2009
10/09/2015
10/09/2015
12/14/2012
10/09/2015
10/09/2015
10/13/2011
09/28/2010
10/13/2011
11/21/2008
10/13/2011
08/12/2010
11/06/2008
10/13/2011
10/13/2011
10/13/2011
09/28/2007

Registration
No.

1143760

837149
1368527
16828287
16189961
1022396
1277705
1,280,146
011054285
1,277,538
1,282,810
009948258
009034349
00948258
006537047
009948092
1048621
006536999
009948118
009948308
009948423
005419031

Status

Registered

Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered

Docket Number

2542-10 AUSTRALIA

2542-10 CANADA
2542-89 Intl/EU
2542-75 EU
2542-72 EU
2542-46 EU
2542-54 INTL/EU
2542-55 INTL/EU
2542-33 EU
2542-62 INTL/EU
2542-63 INTL/EU
2542-42 EU
2542-59 EU
2542-58 EU
2542-41 EU
2542-57 EU
2542-29 EU
2542-47 EU
2542-56 EU
2542-60 EU
2542-61 EU
2542-10 EU

Client Ref No.
8251-8
AUSTRALIA
  8251-8 CANADA  

Country

Australia

Canada
  Community Trademark  
  Community Trademark  
  Community Trademark  
8251-59 EPO
  Community Trademark  
8251-70 MP EU   Community Trademark  
8251-71 MP EU   Community Trademark  
8251-16 CTM   Community Trademark  
8251-72 MP EU   Community Trademark  
8251-73 MP EU   Community Trademark  
8251-52 CTM   Community Trademark  
8251-66 CTM   Community Trademark  
8251-65 CTM   Community Trademark  
8251-51 CTM   Community Trademark  
8251-64 CTM   Community Trademark  
  Community Trademark  
8251-10 EPO
8251-61 EU
  Community Trademark  
8251-62 CTM   Community Trademark  
8251-67 CTM   Community Trademark  
8251-68 CTM   Community Trademark  
  Community Trademark  
8251-8 EPO

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Docket Number
2542-30 INTL/EU
2542-58 UNITED
KINGDOM

2542-30 INTL/ICELAND

2542-89 Intl
2542-54 INTL
2542-55 INTL
2542-62 INTL
2542-63 INTL
2542-30 INTL
2542-89 Intl/UK
2542-84UK
2542-72
2542-54
2542-55
2542-70
2542-9
2542-31
2542-33
2542-32
2542-11
2542-12
2542-10
2542-30
2542-88

8251-65

8251-12 MP
ICELAND

8251-70 MP
8251-71 MP
8251-72 MP
8251-73 MP
8251-12 MP

8251-70
8251-71

8251-14
8251-16
8251-15
8251-11
8251-13
8251-8
8251-12

Client Ref No.
8251-12 MP EU   Community Trademark  

Country

Application Date
11/22/2013

Application No
1,186,977

Registration Date
11/22/2013

Great Britain

11/09/2009

2531080

05/18/2012

Registration
No.
1,186,977

00002531080

Iceland

International
International
International
International
International
International
UK
UK
United States
United States
United States
United States
United States
United States
United States
United States
United States
United States
United States
United States
United States

3594/2013

11/22/2013

1,186,977

A0069009
A0053765
1,280,146
1277538
1,282,810
A0039418
  WE00001368527  
  UK00003238912  
87/078,346
86/593,696
86/593,862
86/677,227
76/978,843
85/207,192
85/524,990
85/207,229
77/728,511
77/728,499
78/871,967
85/105,993
87/343,172

10/09/2015
10/09/2015
10/09/2015
10/09/2015
11/22/2013
1/9/2018
09/08/2017

04/11/2017
04/11/2017
02/14/2017
08/19/2008
04/03/2012
03/04/2014
11/22/2011
10/12/2010
01/10/2012
08/05/2008
05/22/2012

1277705
1/280,146
1277538
1,282,810
1,186,977
1368527
  UK00003238912  

5,182,183
5,182,184
5,142,544
3,489,209
4,120,445
4,491,643
4,058,892
3,862,228
4,085,298
3,482,366
4,147,273

12/19/2013

8/7/2017
10/09/2015
10/09/2015
10/09/2015
10/09/2015
11/22/2013
3/6/2017
06/22/2017
06/21/2016
04/10/2015
04/10/2015
06/29/2015
09/22/2003
12/29/2010
01/25/2012
12/29/2010
05/04/2009
05/04/2009
04/28/2006
08/12/2010
2/21/2017

-2-

Status
Registered

Registered

Registered

Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Filed
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Filed

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

Patents

Australia

Filed

2013329256

10/10/2013

Australia

Granted

2013331402

10/16/2013

Canada

Filed

2,903,728

10/16/2013

Canada

Canada

Filed

Filed

2,926,436

10/07/2014

2,940,655

03/18/2015

Canada

Granted

2,945,710

04/14/2015

Canada

Granted

2,886,472

10/10/2013

Canada

Granted

2,713,101

10/04/2007

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED
COATINGS

SECURITY SYSTEM AND
METHOD OF MARKING AN
INVENTORY ITEM AND/OR
PERSON IN THE VICINITY

SECURITY SYSTEM AND
METHOD OF MARKING AN
INVENTORY ITEM AND/OR
PERSON IN THE VICINITY

  MULTIMODE IMAGE AND

SPECTRAL READER

ENCRYPTED OPTICAL
MARKERS FOR SECURITY
APPLICATIONS

  CONTOUR ENCRYPTION AND

DECRYPTION

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED
COATINGS

  METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE
SYSTEM

-3-

2013331402

02/08/2018

2,945,710

07/11/2017

2,886,472

04/18/2017

2,713,101

09/13/2016

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

Canada

Granted

CA2480069

3/21/2003

China P.R.

Filed

PCT/US2015/025734

04/15/2015

China P.R.

Filed

201580014368.6

03/18/2015

China P.R.

Granted

3155949.2

08/27/2003

China P.R.

Granted

ZL 200780045281 .0

10/04/2007

China P.R.

Granted

31559492

08/27/2003

China P.R.

Granted

00107580.2

05/18/2000

European Patent
Convention

Granted

03007023.9

03/27/2003

-4-

  Marking Apparatus for Nucleic

Acid Marking of Items

  CONTOUR ENCRYPTION AND

DECRYPTION

ENCRYPTED OPTICAL
MARKERS FOR SECURITY
APPLICATIONS

  METHOD OF DISSOLVING
NUCLEIC ACID IN WATER
INSOLUBLE MEDIUM AND ITS
APPLICATION

  METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE
SYSTEM

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

  A METHOD FOR UTILIZING

RIBONUCLEIC ACID AS
MARKERS FOR PRODUCT ANTI-
COUNTERFEITING LABELS

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

480069

7/24/2012

101589157

04/02/2014

356065

08/27/2003

193957

05/18/2000

1394544

03/27/2003

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

Granted

4018374.1

08/03/2004

14852842.5

10/07/2014

15780179.6

04/15/2015

07852534.2

10/04/2007

15765671.1

03/18/2015

156878.3

08/03/2004

  METHOD FOR CONCEALING A
SECRET INFORMATION
CARRIED WITHIN A DNA
MOLECULE AND METHOD FOR
DECODING A SECRET
INFORMATION THAT HAVE
BEEN CONCEALED BY SAID
CONCEALING METHOD

  MULTIMODE IMAGE AND

SPECTRAL READER

  CONTOUR ENCRYPTION AND

DECRYPTION

  METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE
SYSTEM

ENCRYPTED OPTICAL
MARKERS FOR SECURITY
APPLICATIONS

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

Filed

Filed

Filed

Filed

Filed

Filed

16783711.1

09/28/2017

  HYDROPHOBIC NUCLEIC ACID
SALTS AS SECURITY MARKERS

13776001.3

04/05/2013

PLASMA TREATMENT FOR
DNA BINDING

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED
COATINGS

-5-

Filed

13845351.9

10/10/2013

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

European Patent
Convention

Filed

14784907.9

04/18/2014

European Patent
Convention

Filed

Granted

13847647.8

10/16/2013

LASER MARKING FOR
AUTHENTICATION AND
TRACKING

SECURITY SYSTEM AND
METHOD OF MARKING AN
INVENTORY ITEM AND/OR
PERSON IN THE VICINITY

SECURITY SYSTEM AND
METHOD OF MARKING AN
INVENTORY ITEM AND/OR
PERSON IN THE VICINITY

European Patent
Convention

European Patent
Convention

France

France

Granted

Granted

12152848.3

01/27/2012

MARKING COMPOSITION

2482262

09/06/2017

12152848.3

01/27/2012

  MARKING COMPOSITION

2482262

09/06/2017

Granted

4018374.1

08/03/2004

France

Granted

03007023.9

03/27/2003

Germany

Granted

4018374.1

08/03/2004

-6-

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM
AND APPLICATION THEREOF

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM
AND APPLICATION THEREOF

1568783

07/11/2007

1394544

02/04/2009

04018374

07/11/2007

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

Germany

Granted

03007023.9

03/27/2003

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

603 26 065.9

02/04/2009

Germany

Great Britain

Great Britain

Granted

Granted

Granted

12152848.3

12152848.3

613626.1

01/27/2012

  MARKING COMPOSITION

01/27/2012

  MARKING COMPOSITION

07/08/2006

MARKING MATERIAL

2482262

2482262

613626.1

09/06/2017

09/06/2017

07/08/2006

Great Britain

Granted

4018374.1

08/03/2004

Great Britain

Granted

03007023.9

03/27/2003

Great Britain

Granted

GB2390055

3/21/2003

Hong Kong

Granted

10105127.3

10/04/2007

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM
AND APPLICATION THEREOF

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

  Marking Apparatus for Nucleic

Acid Marking of Items

  METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE
SYSTEM

1568783

07/11/2007

1394544

02/04/2009

GB2390055

8/9/2005

1139184

11/14/2014

-7-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

India

Granted

P 002 004 00374

08/04/2004

India

Filed

##############

07/13/2017

Indonesia

Granted

P-002004/00374

08/04/2004

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM
AND APPLICATION THEREOF

  METHOD AND DEVICE FOR

MARKING FIBROUS
MATERIALS

  METHOD FOR CONCEALING A
SECRET INFORMATION
CARRIED WITHIN A DNA
MOLECULE AND METHOD FOR
DECODING A SECRET
INFORMATION THAT HAVE
BEEN CONCEALED BY SAID
CONCEALING METHOD

IDO 0026764

08/04/2004

IDO 0026764

08/04/2004

Ireland

Granted

12152848.3

01/27/2012

  MARKING COMPOSITION

2482262

09/06/2017

Israel

Granted

198028

10/04/2007

Italy

Granted

4018374.1

08/03/2004

Italy

Granted

03007023.9

03/27/2003

Japan

Filed

2017-501090

03/18/2015

  METHOD FOR PERFORMING PCR
IN A CONTINUOUS RAPID
THERMAL CYCLE SYSTEM

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM
AND APPLICATION THEREOF

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

ENCRYPTED OPTICAL
MARKERS FOR SECURITY
APPLICATIONS

-8-

198028

07/06/2015

31679 BE/2007

07/11/2007

1394544

02/04/2009

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

6273379

01/12/2018

4452947

08/04/2004

3930794

08/30/2002

MY-135976-A

07/31/2008

Japan

Granted

2016-562831

10/14/2016

Japan

Granted

2004-225987

08/04/2004

Japan

Granted

2002/294229

08/30/2002

Malaysia

Granted

PI2004/3145

08/04/2004

Patent Cooperation
Treaty

Patent Cooperation
Treaty

Patent Cooperation
Treaty

Patent Cooperation
Treaty

Filed

PCT/US2015/025734

04/14/2015

Filed

PCT/US2015/021165

03/18/2015

Filed

PCT/US18/13549

01/12/2018

Filed

PCT/US17/17049

-9-

  CONTOUR ENCRYPTION AND

DECRYPTION

  METHOD FOR ENCRYPTING
AND DECRYPTING SPECIFIC
MESSAGE BY USING NUCLEIC
ACID MOLECULE

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

  METHOD FOR CONCEALING A
SECRET INFORMATION
CARRIED WITHIN A DNA
MOLECULE AND METHOD FOR
DECODING A SECRET
INFORMATION THAT HAVE
BEEN CONCEALED BY SAID
CONCEALING METHOD

  CONTOUR ENCRYPTION AND

DECRYPTION

ENCRYPTED OPTICAL
MARKERS FOR SECURITY
APPLICATIONS

TRACEABLE NUCLEIC ACID
MARKED FERTILIZER

IDENTIFYING MARKED
ARTICLES IN THE
INTERNATIONAL
STREAM OF COMMERCE

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

Patent Cooperation
Treaty

Filed

PCT/US17/23579

03/22/2017

Peru

Filed

Republic of Korea

Granted

61387/2004

08/04/2004

Switzerland

Granted

4018374.1

08/03/2004

Switzerland

Granted

03007023.9

03/27/2003

Taiwan

Filed

104110480

03/31/2015

Taiwan

Filed

92119302

07/15/2003

-10-

METHOD OF MARKING
CELLULOSIC PRODUCTS

  METHOD AND DEVICE FOR

MARKING FIBROUS
MATERIALS

  METHOD FOR CONCEALING A
SECRET INFORMATION
CARRIED WITHIN A DNA
MOLECULE AND METHOD FOR
DECODING A SECRET
INFORMATION THAT HAVE
BEEN CONCEALED BY SAID
CONCEALING METHOD

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM
AND APPLICATION THEREOF

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

IN-FIELD DNA EXTRACTION,
DETECTION AND
AUTHENTICATION METHODS
AND SYSTEMS THEREFOR

A TRANSFER METHOD OF
REWARD FUND CAPABLE FOR
IDENTIFYING MULTIPLE
TARGETS

4452947

08/04/2004

1568783

07/11/2007

337023

02/04/2009

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

I326308

02/16/2005

I231311

06/12/2000

156878.3

08/04/2004

Taiwan

Granted

2003-0121490

08/06/2003

Taiwan

Granted

89108443

03/17/2000

Taiwan

Granted

89111477

06/12/2000

Thailand

Granted

92819

08/04/2004

Turkey

Filed

2018/03030

3/1/2018

United States

Filed

14/695,228

04/24/2015

United States

Filed

14/570,242

12/15/2014

United States

Filed

14/969,582

12/15/2015

-11-

  METHOD FOR CONCEALING A
SECRET INFORMATION
CARRIED WITHIN A DNA
MOLECULE AND METHOD FOR
DECODING A SECRET
INFORMATION THAT HAVE
BEEN CONCEALED BY SAID
CONCEALING METHOD

  NUCLEIC ACID AS MARKER FOR
PRODUCT ANTI-
COUNTERFETING AND
IDENTIFICATION

  A DEVICE FOR MULTIPLE PCR IN
A CLOSED CONTAINER AND
METHOD OF USING THERFOR

  METHOD FOR CONCEALING A
SECRET INFORMATION
CARRIED WITHIN A DNA
MOLECULE AND METHOD FOR
DECODING A SECRET
INFORMATION THAT HAVE
BEEN CONCEALED BY SAID
CONCEALING METHOD

TRACEABLE NUCLEIC ACID
MARKED FERTILIZER

  METHODS AND SYSTEMS FOR
THE GENERATION OF A
PLURALITY OF SECURITY
MARKERS AND THE
DETECTION THEROF

SECURITY SYSTEM AND
METHOD OF MARKING AN
INVENTORY ITEM AND/OR
PERSON IN THE VICINITY

INCORPORATING SOLUBLE
SECURITY MARKERS INTO
CYANOACRYLATE SOLUTIONS

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

United States

Filed

14/572,552

12/16/2014

United States

Filed

PCT/US2015/066074

12/16/2015

  METHOD AND DEVICE FOR

MARKING FIBROUS
MATERIALS

  METHOD AND DEVICE FOR

MARKING FIBROUS
MATERIALS

ENCRYPTED OPTICAL
MARKERS FOR SECURITY
APPLICATIONS

United States

United States

Filed

Filed

16/028,176

07/05/2018

15/562,495

09/28/2017

  HYDROPHOBIC NUCLEIC ACID
SALTS AS SECURITY MARKERS

United States

Filed

PCT/US2016/022532

03/16/2016

United States

Filed

15/427,983

02/08/2017

United States

United States

Filed

Filed

15/212,429

07/18/2016

15/722,157

10/02/2017

METHOD FOR
AUTHENTICATING ACTIVE
PHARMACEUTICAL
INGREDIENTS

IDENTIFYING MARKED
ARTICLES IN THE
INTERNATIONAL
STREAM OF COMMERCE

PLASMA TREATMENT FOR
DNA BINDING

  COMPOSITION AND METHOD
OF DNA MARKING
ELASTOMERIC MATERIAL

-12-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

United States

Filed

62/575, 926

10/20/2017

United States

United States

United States

Filed

Filed

Filed

15/870,035

01/12/2018

15/868,510

01/11/2018

15/466,016

03/22/2017

United States

Filed

62/524,186

06/23/201

United States

Filed

62/660,158

04/19/2018

United States

Filed

62/625,702

02/02/2018

United States

Filed

62/684,142

06/12/2018

-13-

SYSTEM AND METHOD OF
TAGGING OBJECTS WITH
DETECTABLE NUCLEIC ACID
MARKERS VIA AERIAL
DELIVERY

TRACEABLE NUCLEIC ACID
MARKED FERTILIZER

  MULTIMODE IMAGE AND

SPECTRAL READER

METHOD OF MARKING
CELLULOSIC PRODUCTS

  RAPID AUTHENTICATION OF
PHARMACEUTICALS VIA DNA
TAGGING AND IN-FIELD
DETECTION

SYSTEM AND METHOD FOR
PRODUCING PATIENT-SPECIFIC
ANTIBODIES VIA LINEAR DNA
AMPLICONS

SYSTEM AND METHOD FOR
TRACKING ORIGIN OF
CANNABIS PRODUCTS AND
CANNABIS DERIVATIVE
PRODUCTS

  SYSTEMS AND METHODS FOR
PRODUCING PATIENT-SPECIFIC
TUMOR ANTIGENS VIA LINEAR
DNA AMPLICONS

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

United States

United States

Filed

Filed

16/028,176

07/05/2018

62/700,021

07/18/2018

United States

Granted

15/027,454

04/06/2016

United States

Granted

10/748,412

12/29/2003

United States

Granted

11/954,038

12/11/2007

United States

Granted

11/954,044

12/11/2007

United States

Granted

11/954,051

12/11/2007

United States

Granted

11/954,030

12/11/2007

ENCRYPTED OPTICAL
MARKERS FOR SECURITY
APPLICATIONS

  PLANT MATERIAL SPRAYING
SYSTEM

  MULTIMODE IMAGE AND

SPECTRAL READER

  METHOD OF MARKING SOLID
OR LIQUID SUBSTANCES WITH
NUCLEIC ACID FOR ANTI-
COUNTERFEITING AND
AUTHENTICATION

METHODS FOR
AUTHENTICATING ARTICLES
WITH OPTICAL REPORTERS

SYSTEM AND METHOD FOR
SECURE DOCUMENT PRINTING
AND DETECTION

SYSTEM AND METHOD FOR
AUTHENTICATING SPORTS
IDENTIFICATION GOODS

OPTICAL REPORTER
COMPOSITIONS

-14-

9,904,734

02/27/2018

7,115,301

10/03/2006

8,426,216

04/23/2013

8,415,164

04/09/2013

8,415,165

04/09/2013

8,372,648

02/12/2013

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

United States

Granted

13/761,447

02/07/2013

United States

Granted

14/253,641

04/15/2014

United States

Granted

11/954,009

12/11/2007

OPTICAL REPORTER
COMPOSITIONS

9,005,985

04/14/2015

  CONTOUR ENCRYPTION AND

DECRYPTION

  METHODS FOR COVALENT

LINKING OF OPTICAL
REPORTERS

9,412,284

08/09/2016

8,124,333

02/28/2012

United States

Granted

12/307,488

10/26/2009

MARKING MATERIAL

9,171,443

10/27/2015

United States

Granted

13/648,594

10/10/2012

United States

Granted

14/497,614

09/26/2014

United States

Granted

15/079,214

03/24/2016

United States

Granted

14/661,489

03/18/2015

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED
COATINGS

  METHOD AND DEVICE FOR

MARKING ARTICLES

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED
COATINGS

ENCRYPTED OPTICAL
MARKERS FOR SECURITY
APPLICATIONS

9,297,032

03/29/2016

9,963,740

05/08/2018

10,047,282

08/14/2018

-15-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Country

Status

Application No.

Application Date

Title

Patent Number

Grant Date

Various EU Members

Granted

312388.2

3/21/3003

Vietnam

Granted

1-2004-00742

08/04/2004

  Marking Apparatus for Nucleic

Acid Marking of Items

  METHOD FOR CONCEALING A
SECRET INFORMATION
CARRIED WITHIN A DNA
MOLECULE AND METHOD FOR
DECODING A SECRET
INFORMATION THAT HAVE
BEEN CONCEALED BY SAID
CONCEALING METHOD

EP1488039

3/9/2006

9182

08/04/2004

-16-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
None.

SCHEDULE V

Commercial Tort Claims

 
 
 
 
 
 
Location, Chief Executive Office, Type of Organization, Jurisdiction of Organization and Organizational Identification Number

SCHEDULE VI

50 Health Sciences Drive
Stony Brook, New York 11790

Registered Office

P.O. Box 3170
Nemours Chambers
Road Town, Tortola
British Virgin Islands, VG1110

Type of Organization - Corporation

Jurisdiction of Organization - British Virgin Islands

Organizational Identification Number - 656029

 
 
 
 
 
 
 
 
 
 
 
None.

SCHEDULE VII

Changes in Name, Location, Etc.

 
 
 
 
 
 
SCHEDULE VIII

Locations of Equipment, Inventory and Books and Records

·

·

·

50 Health Sciences Drive
Stony Brook, New York 11790

Registered Office

P.O. Box 3170
Nemours Chambers
Road Town, Tortola
British Virgin Islands, VG1110

 
 
 
 
 
 
 
 
 
 
 
 
 
None.

SCHEDULE IX

Letters of Credit

 
 
 
 
 
 
None.

SCHEDULE X

Permitted Liens

 
 
 
 
 
 
SCHEDULE XI

Excluded Assets

· Mexico Patent No. MX/a/2015/012210 for DNA Marking of Previously Undistinguished Items for Traceability

· US Patent Application No. 15/890,541 for Nucleic Acid Coated Submicron Particles for Authentication

·

PCT Application No. PCT/US18/17164 for Acid Coated Submicron Particles for Authentication

· US Patent Application No. 15/553,246 for Method for Authentication Active Pharmaceutical Ingredients

· US Patent Application No. 15/800,768 for Method for Authentication Active Pharmaceutical Ingredients

· US Patent No. 8,420,400 for System and Method for Authenticating Tablets

· US Patent No. 9,266,370 DNA Marking for Previously Undistinguished Items for Traceability

 
 
 
 
 
 
 
 
 
 
 
 
EXHIBIT 10.43

EXECUTION VERSION

INTELLECTUAL PROPERTY SECURITY AGREEMENT

This INTELLECTUAL PROPERTY SECURITY AGREEMENT (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “IP Security Agreement”) dated October 19, 2018, is made by APPLIED DNA SCIENCES, INC. a Delaware corporation (the “Grantor”), in favor of DELAWARE TRUST
COMPANY, a Delaware corporation, as collateral agent (the “Collateral Agent”) for the Secured Parties (as defined in the Security Agreement referred to below).

otherwise modified from time to time, the “Securities Purchase Agreement”) with the Buyers party thereto.

WHEREAS, Grantor is party to the Securities Purchase Agreement dated as of August 31, 2018 (as amended, restated, amended and restated, supplemented or

WHEREAS, pursuant to the Securities Purchase Agreement, the Grantor has executed and delivered that certain Security Agreement dated as of October 19, 2018
made by the Grantor to the Collateral Agent for the benefit of the Secured Parties (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “Security Agreement”; the capitalized terms defined therein and not otherwise defined herein being used herein as therein defined).

WHEREAS, under the terms of the Security Agreement, the Grantor has granted to the Collateral Agent, for the ratable benefit of the Secured Parties, a security
interest in, among other property, certain intellectual property of the Grantor, and have agreed as a condition thereof to execute this IP Security Agreement for recording with the
U.S. Patent and Trademark Office, the United States Copyright Office and other governmental authorities.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Grantor agrees as follows:

right, title and interest in and to the following (the “Collateral”):

SECTION 1. Grant of Security. Grantor hereby grants to the Collateral Agent for the ratable benefit of the Secured Parties a security interest in all of Grantor’s

(i)        all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all improvements

thereto, including, without limitation, those set forth in Schedule A hereto (the “Patents”);

(ii)       all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and other source
identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent that, and solely
during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under applicable federal
law), together, in each case, with the goodwill symbolized thereby, including, without limitation, those set forth in Schedule B hereto (the “Trademarks”);

 
 
 
 
 
 
 
 
 
 
 
 
(iii)      all copyrights, including, without limitation, copyrights in Computer Software (as hereinafter defined), internet web sites and the content thereof, whether
registered  or  unregistered,  including,  without  limitation,  the  copyright  registrations  and  applications  and  exclusive  copyright  licenses  set  forth  in Schedule  C  hereto  (the
“Copyrights”);

(iv)      all reissues, divisions, continuations, continuations-in-part, extensions, renewals and reexaminations of any of the foregoing, all rights in the foregoing
provided by international treaties or conventions, all rights corresponding thereto throughout the world and all other rights of any kind whatsoever of Grantor accruing thereunder
or pertaining thereto;

respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages; and

(v)       any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation, misuse or breach with

(vi)      any and all proceeds of, collateral for, income, royalties and other payments now or hereafter due and payable with respect to, and supporting Obligations

(as defined in the Security Agreement) relating to, any and all of the Collateral of or arising from any of the foregoing.

SECTION  2. Security for Obligations. The grant of a security interest in the Collateral by Grantor under this IP Security Agreement secures the payment of all
Secured Obligations now or hereafter existing under or in respect of the Transaction Documents, whether direct or indirect, absolute or contingent, and whether for principal,
reimbursement obligations, interest, premiums, penalties, fees, indemnifications, contract causes of action, costs, expenses or otherwise. Without limiting the generality of the
foregoing, this IP Security Agreement secures, as to Grantor, the payment of all amounts that constitute part of the Secured Obligations and that would be owed by Grantor to any
Secured  Party  under  the  Transaction  Documents  but  for  the  fact  that  such  Secured  Obligations  are  unenforceable  or  not  allowable  due  to  the  existence  of  a  bankruptcy,
reorganization or similar proceeding involving Grantor.

and any other applicable government officer record this IP Security Agreement.

SECTION 3. Recordation. Grantor authorizes and requests that the Register of Copyrights, the Commissioner for Patents and the Commissioner for Trademarks

deemed to be an original and all of which taken together shall constitute one and the same agreement.

SECTION 4. Execution in Counterparts. This IP Security Agreement may be executed in any number of counterparts, each of which when so executed shall be

SECTION  5. Grants, Rights and Remedies. This IP Security Agreement has been entered into in conjunction with the provisions of the Security Agreement.
Grantor does hereby acknowledge and confirm that the grant of the security interest hereunder to, and the rights and remedies of, the Collateral Agent with respect to the Collateral
are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated herein by reference as if fully set forth herein.

 
 
 
 
 
 
 
 
 
 
SECTION 6. GOVERNING LAW. THIS IP SECURITY AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS

OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS.

[remainder of page intentionally blank]

 
 
 
 
IN WITNESS WHEREOF, Grantor has caused this IP Security Agreement to be duly executed and delivered by its officer thereunto duly authorized as of the date

first above written.

APPLIED DNA SCIENCES, INC.

/s/ Beth Jantzen

By
Name: Beth Jantzen, CPA
Title:

Chief Financial Officer

Address for Notices:

50 Health Sciences Drive
Stony Brook, NY 11790
Attn: Beth Jantzen, CPA
Facsimile: 631-240-8900

with a copy to:

Pepper Hamilton LLP
The New York Times Building
37th Floor
620 Eighth Avenue
New York, NY 10018-1405
Attention: Merrill M. Kraines
E-mail: krainesm@pepperlaw.com

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
SCHEDULE A

PATENTS

 Country

United
States

Status

Granted

Application
 No.

Application
 Date

12/384,554

04/06/2009

Title

Patent No.

Grant Date

METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE
SYSTEM

8,163,489

04/24/2012

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Client Ref 
No.

8251-61
2542-75

 Docket No.
2542-83
2542-82
2542-47
2542-75
2542-95
2542-89
2542-84
2542-89A  

:

Country
United States
United States
United States
United States
United States
United States
United States
United States

SCHEDULE B

TRADEMARKS

 Application
Date
12/13/2016
12/20/2016
06/09/2008
12/09/2016
5/16/2017
3/6/2017
12/23/2016
8/16/2017

Application
No.
87/267,216
87/275,103
77/494,134
87/263,954
87/451,220
87/360,183
87/279,792
87/571,726

 Registration
Date

12/12/2017
01/05/2010
05/23/2017

10/17/2017
08/22/2017

 Registration No.

5,356,414
3,735,415
5,209,527

5,313,762
5,269,735

Status
Filed
Registered
Registered
Registered
Filed
Registered
Registered
Filed

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
None.

SCHEDULE C

COPYRIGHTS

 
 
 
 
 
 
 
 
Exhibit 10.44

EXECUTION VERSION

INTELLECTUAL PROPERTY SECURITY AGREEMENT

This INTELLECTUAL PROPERTY SECURITY AGREEMENT (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “IP Security Agreement”) dated October 19, 2018, is made by APDN (B.V.I.) Inc., a corporation formed under the laws of the British Virgin Islands (the “ Grantor”), in favor
of  DELAWARE  TRUST  COMPANY,  a  Delaware  corporation,  as  collateral  agent  (the  “ Collateral Agent”)  for  the  Secured  Parties  (as  defined  in  the  Guaranty  and  Security
Agreement referred to below).

WHEREAS, Grantor is a wholly owned subsidiary of APPLIED DNA SCIENCES, a Delaware corporation (the “Company”) and the  Company is party to the
Securities Purchase Agreement dated as of August 31, 2018 (as amended, restated, amended and restated, supplemented or otherwise modified from time to time, the “ Securities
Purchase Agreement”) with the Buyers party thereto.

WHEREAS, pursuant to the Securities Purchase Agreement, the Grantor has executed and delivered that certain Guaranty and Security Agreement, dated as of
the date hereof, made by the  Grantor to the  Collateral Agent for the benefit of the  Secured  Parties (as amended, restated, amended and restated, supplemented or otherwise
modified from time to time, the “Security Agreement”; the capitalized terms defined therein and not otherwise defined herein being used herein as therein defined).

WHEREAS, under the terms of the Security Agreement, the Grantor has granted to the Collateral Agent, for the ratable benefit of the Secured Parties, a security
interest in, among other property, certain intellectual property of the Grantor, and have agreed as a condition thereof to execute this IP Security Agreement for recording with the
U.S. Patent and Trademark Office, the United States Copyright Office and other governmental authorities.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Grantor agrees as follows:

SECTION 1.      Grant of Security. Grantor hereby grants to the Collateral Agent for the ratable benefit of the Secured Parties a security interest in all of Grantor’s

right, title and interest in and to the following (the “Collateral”):

(i)       all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all improvements

thereto, including, without limitation, those set forth in Schedule A hereto (the “Patents”);

(ii)       all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and other source
identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent that, and solely
during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under applicable federal
law), together, in each case, with the goodwill symbolized thereby, including, without limitation, those set forth in Schedule B hereto (the “Trademarks”);

 
 
 
 
 
 
 
 
 
 
 
 
 
 
(iii)       all copyrights, including, without limitation, copyrights in Computer Software (as hereinafter defined), internet web sites and the content thereof, whether
registered  or  unregistered,  including,  without  limitation,  the  copyright  registrations  and  applications  and  exclusive  copyright  licenses  set  forth  in Schedule  C  hereto  (the
“Copyrights”);

(iv)       all reissues, divisions, continuations, continuations-in-part, extensions, renewals and reexaminations of any of the foregoing, all rights in the foregoing
provided by international treaties or conventions, all rights corresponding thereto throughout the world and all other rights of any kind whatsoever of Grantor accruing thereunder
or pertaining thereto;

(v)       any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation, misuse or breach with

respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages; and

(as defined in the Security Agreement) relating to, any and all of the Collateral of or arising from any of the foregoing.

(vi)       any and all proceeds of, collateral for, income, royalties and other payments now or hereafter due and payable with respect to, and supporting Obligations

SECTION  2.      Security for Obligations. The grant of a security interest in the Collateral by Grantor under this IP Security Agreement secures the payment of all
Secured Obligations now or hereafter existing under or in respect of the Transaction Documents, whether direct or indirect, absolute or contingent, and whether for principal,
reimbursement obligations, interest, premiums, penalties, fees, indemnifications, contract causes of action, costs, expenses or otherwise. Without limiting the generality of the
foregoing, this IP Security Agreement secures, as to Grantor, the payment of all amounts that constitute part of the Secured Obligations and that would be owed by Grantor to any
Secured  Party  under  the  Transaction  Documents  but  for  the  fact  that  such  Secured  Obligations  are  unenforceable  or  not  allowable  due  to  the  existence  of  a  bankruptcy,
reorganization or similar proceeding involving Grantor.

SECTION 3.      Recordation. Grantor authorizes and requests that the Register of Copyrights, the Commissioner for Patents and the Commissioner for Trademarks

and any other applicable government officer record this IP Security Agreement.

deemed to be an original and all of which taken together shall constitute one and the same agreement.

SECTION 4.      Execution in Counterparts. This IP Security Agreement may be executed in any number of counterparts, each of which when so executed shall be

SECTION  5.     Grants, Rights and Remedies. This IP Security Agreement has been entered into in conjunction with the provisions of the Security Agreement.
Grantor does hereby acknowledge and confirm that the grant of the security interest hereunder to, and the rights and remedies of, the Collateral Agent with respect to the Collateral
are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated herein by reference as if fully set forth herein.

-2-

 
 
 
 
 
 
 
 
 
 
 
 
 
LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS.

SECTION  6.      GOVERNING LAW. THIS IP SECURITY AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE

[remainder of page intentionally blank]

-3-

 
 
 
 
 
 
IN WITNESS WHEREOF, Grantor has caused this IP Security Agreement to be duly executed and delivered by its officer thereunto duly authorized as of the date

first above written.

APDN (B.V.I.) INC.,
a corporation formed under the laws of the British Virgin Islands

By:
Name:
Title:

/s/ James A. Hayward
James A. Hayward
Authorized Signatory

Address for Notices:

50 Health Sciences Drive
Stony Brook, NY 11790
Attn: Beth Jantzen, CPA
Facsimile: 631-240-8900

with a copy to:

Pepper Hamilton LLP
The New York Times Building
37th Floor
620 Eighth Avenue
New York, NY  10018-1405
Attention: Merrill M. Kraines
E-mail: krainesm@pepperlaw.com

-4-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
SCHEDULE A

Patents

 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

Australia

Filed

2013329256

10/10/2013

Australia

Granted

2013331402

10/16/2013

Canada

Canada

Canada

Canada

Filed

Filed

Filed

2,903,728

10/16/2013

2,926,436

10/07/2014

2,940,655

03/18/2015

Granted

2,945,710

04/14/2015

Canada

Granted

2,886,472

10/10/2013

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED COATINGS   

SECURITY SYSTEM AND METHOD
OF MARKING AN INVENTORY
ITEM AND/OR PERSON IN THE
VICINITY

SECURITY SYSTEM AND METHOD
OF MARKING AN INVENTORY
ITEM AND/OR PERSON IN THE
VICINITY

MULTIMODE IMAGE AND
SPECTRAL READER

ENCRYPTED OPTICAL MARKERS
FOR SECURITY APPLICATIONS

CONTOUR ENCRYPTION AND
DECRYPTION

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED COATINGS

-5-

2013331402

02/08/2018

2,945,710

07/11/2017

2,886,472

04/18/2017

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

Application No.

  Application Date  

Title

  Patent Number  

Grant Date

Canada

Canada

Granted

2,713,101

10/04/2007

Granted

CA2480069

3/21/2003

China P.R.

Filed

  PCT/US2015/025734  

04/15/2015

China P.R.

Filed

201580014368.6

03/18/2015

China P.R.

Granted

3155949.2

08/27/2003

China P.R.

Granted

  ZL 200780045281 .0  

10/04/2007

China P.R.

Granted

31559492

08/27/2003

China P.R.

Granted

00107580.2

05/18/2000

METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE SYSTEM

Marking Apparatus for Nucleic Acid
Marking of Items

CONTOUR ENCRYPTION AND
DECRYPTION

ENCRYPTED OPTICAL MARKERS
FOR SECURITY APPLICATIONS

METHOD OF DISSOLVING NUCLEIC
ACID IN WATER INSOLUBLE
MEDIUM AND ITS APPLICATION

METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE SYSTEM

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

A METHOD FOR UTILIZING
RIBONUCLEIC ACID AS MARKERS
FOR PRODUCT ANTI-
COUNTERFEITING LABELS

2,713,101

09/13/2016

480069

7/24/2012

101589157

04/02/2014

356065

08/27/2003

193957

05/18/2000

-6-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

1394544

03/27/2003

156878.3

08/03/2004

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

European Patent
Convention

Granted

03007023.9

03/27/2003

Granted

4018374.1

08/03/2004

Filed

Filed

Filed

Filed

Filed

Filed

14852842.5

10/07/2014

15780179.6

04/15/2015

07852534.2

10/04/2007

15765671.1

03/18/2015

16783711.1

09/28/2017

13776001.3

04/05/2013

-7-

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

METHOD FOR CONCEALING A
SECRET INFORMATION CARRIED
WITHIN A DNA MOLECULE AND
METHOD FOR DECODING A
SECRET INFORMATION THAT
HAVE BEEN CONCEALED BY SAID
CONCEALING METHOD

MULTIMODE IMAGE AND
SPECTRAL READER

CONTOUR ENCRYPTION AND
DECRYPTION

METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE SYSTEM

ENCRYPTED OPTICAL MARKERS
FOR SECURITY APPLICATIONS

HYDROPHOBIC NUCLEIC ACID
SALTS AS SECURITY MARKERS

PLASMA TREATMENT FOR DNA
BINDING 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

European Patent
Convention

European Patent
Convention

Filed

13845351.9

10/10/2013

Filed

14784907.9

04/18/2014

European Patent
Convention

Filed

Granted

13847647.8

10/16/2013

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED COATINGS

LASER MARKING FOR
AUTHENTICATION AND
TRACKING

SECURITY SYSTEM AND METHOD
OF MARKING AN INVENTORY
ITEM AND/OR PERSON IN THE
VICINITY

SECURITY SYSTEM AND METHOD
OF MARKING AN INVENTORY
ITEM AND/OR PERSON IN THE
VICINITY

European Patent
Convention

European Patent
Convention

France

France

Granted

Granted

12152848.3

01/27/2012

MARKING COMPOSITION

2482262

09/06/2017

12152848.3

01/27/2012

MARKING COMPOSITION

2482262

09/06/2017

Granted

4018374.1

08/03/2004

France

Granted

03007023.9

03/27/2003

-8-

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM AND
APPLICATION THEREOF

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

1568783

07/11/2007

1394544

02/04/2009

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

Germany

Granted

4018374.1

08/03/2004

Germany

Granted

03007023.9

03/27/2003

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM AND
APPLICATION THEREOF

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

Germany

Great Britain

Great Britain

Granted

Granted

Granted

12152848.3

01/27/2012

MARKING COMPOSITION

12152848.3

01/27/2012

MARKING COMPOSITION

613626.1

07/08/2006

MARKING MATERIAL

Great Britain

Granted

4018374.1

08/03/2004

Great Britain

Granted

03007023.9

03/27/2003

Great Britain

Granted

GB2390055

3/21/2003

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM AND
APPLICATION THEREOF

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

Marking Apparatus for Nucleic Acid
Marking of Items

04018374

07/11/2007

603 26 065.9

2482262

2482262

613626.1

02/04/2009

09/06/2017

09/06/2017

07/08/2006

1568783

07/11/2007

1394544

02/04/2009

GB2390055

8/9/2005

-9-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

Hong Kong

Granted

10105127.3

10/04/2007

India

India

Granted

P 002 004 00374  

08/04/2004

Filed

  ##############  

07/13/2017

Indonesia

Granted

P-002004/00374  

08/04/2004

METHOD FOR A CONTINUOUS
RAPID THERMAL CYCLE SYSTEM

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM AND
APPLICATION THEREOF

METHOD AND DEVICE FOR
MARKING FIBROUS MATERIALS

METHOD FOR CONCEALING A
SECRET INFORMATION CARRIED
WITHIN A DNA MOLECULE AND
METHOD FOR DECODING A
SECRET INFORMATION THAT
HAVE BEEN CONCEALED BY SAID
CONCEALING METHOD

1139184

11/14/2014

IDO  0026764

08/04/2004

IDO  0026764

08/04/2004

Ireland

Israel

Italy

Italy

Granted

12152848.3

01/27/2012

MARKING COMPOSITION

2482262

09/06/2017

Granted

198028

10/04/2007

Granted

4018374.1

08/03/2004

Granted

03007023.9

03/27/2003

METHOD FOR PERFORMING PCR IN
A CONTINUOUS RAPID THERMAL
CYCLE SYSTEM

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM AND
APPLICATION THEREOF

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

198028

07/06/2015

31679  BE/2007  

07/11/2007

1394544

02/04/2009

-10-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

Application No.

  Application Date  

Title

  Patent Number  

Grant Date

Japan

Japan

Japan

Filed

2017-501090

03/18/2015

Granted

2016-562831

10/14/2016

Granted

2004-225987

08/04/2004

Japan

Granted

2002/294229

08/30/2002

Malaysia

Granted

PI2004/3145

08/04/2004

Patent Cooperation
Treaty

Patent Cooperation
Treaty

Patent Cooperation
Treaty

Filed

  PCT/US2015/025734  

04/14/2015

Filed

  PCT/US2015/021165  

03/18/2015

Filed

PCT/US18/13549  

01/12/2018

-11-

ENCRYPTED OPTICAL MARKERS
FOR SECURITY APPLICATIONS

CONTOUR ENCRYPTION AND
DECRYPTION

METHOD FOR ENCRYPTING AND
DECRYPTING SPECIFIC MESSAGE
BY USING NUCLEIC ACID
MOLECULE

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

METHOD FOR CONCEALING A
SECRET INFORMATION CARRIED
WITHIN A DNA MOLECULE AND
METHOD FOR DECODING A
SECRET INFORMATION THAT
HAVE BEEN CONCEALED BY SAID
CONCEALING METHOD

CONTOUR ENCRYPTION AND
DECRYPTION

ENCRYPTED OPTICAL MARKERS
FOR SECURITY APPLICATIONS

TRACEABLE NUCLEIC ACID
MARKED FERTILIZER

6273379

01/12/2018

4452947

08/04/2004

3930794

08/30/2002

  MY-135976-A  

07/31/2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

Patent Cooperation
Treaty

Patent Cooperation
Treaty

Filed

  PCT/US17/17049  

Filed

  PCT/US17/23579  

03/22/2017

Peru

Filed

Republic of Korea

Granted

61387/2004

08/04/2004

Switzerland

Granted

4018374.1

08/03/2004

Switzerland

Granted

03007023.9

03/27/2003

Taiwan

Filed

104110480

03/31/2015

Taiwan

Filed

92119302

07/15/2003

-12-

IDENTIFYING MARKED ARTICLES
IN THE INTERNATIONAL
STREAM OF COMMERCE

METHOD OF MARKING
CELLULOSIC PRODUCTS  

METHOD AND DEVICE FOR
MARKING FIBROUS MATERIALS

METHOD FOR CONCEALING A
SECRET INFORMATION CARRIED
WITHIN A DNA MOLECULE AND
METHOD FOR DECODING A
SECRET INFORMATION THAT
HAVE BEEN CONCEALED BY SAID
CONCEALING METHOD

A NUCLEIC ACID BASED
STEGANOGRAPHY SYSTEM AND
APPLICATION THEREOF

METHOD FOR MIXING
RIBONUCLEIC ACID IN WATER-
INSOLUBLE MEDIUM AND
UTILIZATION THEREOF

IN-FIELD DNA EXTRACTION,
DETECTION AND
AUTHENTICATION METHODS AND
SYSTEMS THEREFOR

A TRANSFER METHOD OF
REWARD FUND CAPABLE FOR
IDENTIFYING MULTIPLE TARGETS

4452947

08/04/2004

1568783

07/11/2007

337023

02/04/2009

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

Taiwan

Granted

2003-0121490

08/06/2003

Taiwan

Granted

89108443

03/17/2000

Taiwan

Granted

89111477

06/12/2000

Thailand

Granted

92819

08/04/2004

METHOD FOR CONCEALING A
SECRET INFORMATION CARRIED
WITHIN A DNA MOLECULE AND
METHOD FOR DECODING A
SECRET INFORMATION THAT
HAVE BEEN CONCEALED BY SAID
CONCEALING METHOD

NUCLEIC ACID AS MARKER FOR
PRODUCT ANTI-COUNTERFETING
AND IDENTIFICATION

A DEVICE FOR MULTIPLE PCR IN A
CLOSED CONTAINER AND
METHOD OF USING THERFOR

METHOD FOR CONCEALING A
SECRET INFORMATION
CARRIED   WITHIN A DNA
MOLECULE AND METHOD FOR
DECODING A SECRET
INFORMATION THAT HAVE BEEN
CONCEALED BY SAID
CONCEALING METHOD

I326308

02/16/2005

I231311

06/12/2000

156878.3

08/04/2004

Turkey

United States

Filed

Filed

14/695,228

04/24/2015

2018/03030

3/1/2018

TRACEABLE NUCLEIC ACID
MARKED FERTILIZER

United States

Filed

14/570,242

12/15/2014

-13-

METHODS AND SYSTEMS FOR THE
GENERATION OF A PLURALITY OF
SECURITY MARKERS AND THE
DETECTION THEROF

SECURITY SYSTEM AND METHOD
OF MARKING AN INVENTORY
ITEM AND/OR PERSON IN THE
VICINITY

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

Application No.

  Application Date  

Title

  Patent Number  

Grant Date

United States

United States

Filed

Filed

14/969,582

12/15/2015

14/572,552

12/16/2014

United States

Filed

  PCT/US2015/066074  

12/16/2015

United States

United States

Filed

Filed

16/028,176

07/05/2018

15/562,495

09/28/2017

United States

Filed

  PCT/US2016/022532  

03/16/2016

United States

United States

Filed

Filed

15/427,983

02/08/2017

15/212,429

07/18/2016

INCORPORATING SOLUBLE
SECURITY MARKERS INTO
CYANOACRYLATE SOLUTIONS

METHOD AND DEVICE FOR
MARKING FIBROUS MATERIALS

METHOD AND DEVICE FOR
MARKING FIBROUS MATERIALS

ENCRYPTED OPTICAL MARKERS
FOR SECURITY APPLICATIONS

HYDROPHOBIC NUCLEIC ACID
SALTS AS SECURITY MARKERS

METHOD FOR AUTHENTICATING
ACTIVE PHARMACEUTICAL
INGREDIENTS

IDENTIFYING MARKED ARTICLES
IN THE INTERNATIONAL STREAM
OF COMMERCE

PLASMA TREATMENT FOR DNA
BINDING

-14-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

United States

Filed

15/722,157

10/02/2017

United States

United States

United States

United States

United States

Filed

Filed

Filed

Filed

Filed

62/575, 926

10/20/2017

15/870,035

01/12/2018

15/868,510

01/11/2018

15/466,016

03/22/2017

62/524,186

06/23/201

United States

Filed

62/660,158

04/19/2018

United States

Filed

62/625,702

02/02/2018

COMPOSITION AND METHOD OF
DNA MARKING ELASTOMERIC
MATERIAL

SYSTEM AND METHOD OF
TAGGING OBJECTS WITH
DETECTABLE NUCLEIC ACID
MARKERS VIA AERIAL DELIVERY

TRACEABLE NUCLEIC ACID
MARKED FERTILIZER

MULTIMODE IMAGE AND
SPECTRAL READER

METHOD OF MARKING
CELLULOSIC PRODUCTS  

RAPID AUTHENTICATION OF
PHARMACEUTICALS VIA DNA
TAGGING AND IN-FIELD
DETECTION

SYSTEM AND METHOD FOR
PRODUCING PATIENT-SPECIFIC
ANTIBODIES VIA LINEAR DNA
AMPLICONS

SYSTEM AND METHOD FOR
TRACKING ORIGIN OF CANNABIS
PRODUCTS AND CANNABIS
DERIVATIVE PRODUCTS

-15-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

United States

United States

United States

Filed

Filed

Filed

62/684,142

06/12/2018

16/028,176

07/05/2018

62/700,021

07/18/2018

United States

Granted

15/027,454

04/06/2016

United States

Granted

10/748,412

12/29/2003

United States

Granted

11/954,038

12/11/2007

United States

Granted

11/954,044

12/11/2007

United States

Granted

11/954,051

12/11/2007

SYSTEMS AND METHODS FOR
PRODUCING PATIENT-SPECIFIC
TUMOR ANTIGENS VIA LINEAR
DNA AMPLICONS

ENCRYPTED OPTICAL MARKERS
FOR SECURITY APPLICATIONS

PLANT MATERIAL SPRAYING
SYSTEM

MULTIMODE IMAGE AND
SPECTRAL READER

METHOD OF MARKING SOLID OR
LIQUID SUBSTANCES WITH
NUCLEIC ACID FOR ANTI-
COUNTERFEITING AND
AUTHENTICATION

METHODS FOR AUTHENTICATING
ARTICLES WITH OPTICAL
REPORTERS

SYSTEM AND METHOD FOR
SECURE DOCUMENT PRINTING
AND DETECTION

SYSTEM AND METHOD FOR
AUTHENTICATING SPORTS
IDENTIFICATION GOODS

-16-

9,904,734

02/27/2018

7,115,301

10/03/2006

8,426,216

04/23/2013

8,415,164

04/09/2013

8,415,165

04/09/2013

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

United States

Granted

11/954,030

12/11/2007

United States

Granted

13/761,447

02/07/2013

OPTICAL REPORTER
COMPOSITIONS

OPTICAL REPORTER
COMPOSITIONS

8,372,648

02/12/2013

9,005,985

04/14/2015

United States

Granted

14/253,641

04/15/2014

CONTOUR ENCRYPTION AND
DECRYPTION

9,412,284

08/09/2016

United States

United States

Granted

Granted

11/954,009

12/11/2007

METHODS FOR COVALENT
LINKING OF OPTICAL REPORTERS

8,124,333

02/28/2012

12/307,488

10/26/2009

MARKING MATERIAL

9,171,443

10/27/2015

United States

Granted

13/648,594

10/10/2012

United States

Granted

14/497,614

09/26/2014

United States

Granted

15/079,214

03/24/2016

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED COATINGS

METHOD AND DEVICE FOR
MARKING ARTICLES

USE OF PERTURBANTS TO
FACILITATE INCORPORATION
AND RECOVERY OF TAGGANTS
FROM POLYMERIZED COATINGS

9,297,032

03/29/2016

9,963,740

05/08/2018

-17-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Country

Status

  Application No.

  Application Date  

Title

Patent Number  

Grant Date

United States

Granted

14/661,489

03/18/2015

Various EU Members

Granted

312388.2

3/21/3003

Vietnam

Granted

1-2004-00742

08/04/2004

ENCRYPTED OPTICAL MARKERS
FOR SECURITY APPLICATIONS

Marking Apparatus for Nucleic Acid
Marking of Items

METHOD FOR CONCEALING A
SECRET INFORMATION CARRIED
WITHIN A DNA MOLECULE AND
METHOD FOR DECODING A
SECRET INFORMATION THAT
HAVE BEEN CONCEALED BY SAID
CONCEALING METHOD

10,047,282

08/14/2018

EP1488039

3/9/2006

9182

08/04/2004

-18-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Docket Number

Client Ref No.

  8251-8 AUSTRALIA  

Country

Australia

2542-10
AUSTRALIA
2542-10 CANADA  

2542-89 Intl/EU
2542-75 EU
2542-72 EU
2542-46 EU
2542-54 INTL/EU  
2542-55 INTL/EU  
2542-33 EU
2542-62 INTL/EU  
2542-63 INTL/EU  
2542-42 EU
2542-59 EU
2542-58 EU
2542-41 EU
2542-57 EU
2542-29 EU
2542-47 EU
2542-56 EU
2542-60 EU
2542-61 EU
2542-10 EU
2542-30 INTL/EU  
2542-58 UNITED
KINGDOM
2542-30
INTL/ICELAND

8251-8 CANADA  

Canada
  Community Trademark  
  Community Trademark  
  Community Trademark  
  Community Trademark  
8251-59 EPO
8251-70 MP EU   Community Trademark  
8251-71 MP EU   Community Trademark  
8251-16 CTM   Community Trademark  
8251-72 MP EU   Community Trademark  
8251-73 MP EU   Community Trademark  
8251-52 CTM   Community Trademark  
8251-66 CTM   Community Trademark  
8251-65 CTM   Community Trademark  
8251-51 CTM   Community Trademark  
8251-64 CTM   Community Trademark  
  Community Trademark  
8251-10 EPO
  Community Trademark  
8251-61 EU
8251-62 CTM   Community Trademark  
8251-67 CTM   Community Trademark  
8251-68 CTM   Community Trademark  
  Community Trademark  
8251-8 EPO
8251-12 MP EU   Community Trademark  

Great Britain

8251-65

8251-12 MP
ICELAND

SCHEDULE B

Trademarks

   Application Date   Application No    Registration Date  

 Registration No.

10/27/2006

10/26/2006
8/16/2017
6/9/2017
12/20/2016
11/09/2009
10/09/2015
10/09/2015
07/19/2012
10/09/2015
10/09/2015
05/09/2011
04/16/2010
05/06/2011
12/07/2007
05/06/2011
08/12/2010
12/07/2007
05/06/2011
05/06/2011
05/06/2011
10/26/2006
11/22/2013

11/09/2009

1143760

1321773
1368527
16828287
16189961
1022396
1277705
1,280,146
011054285
1,277,538
1,282,810
009948258
009034349
00948258
006537047
009948092
1048621
006536999
009948118
009948308
009948423
005419031
1,186,977

2531080

09/29/2008

11/28/2012
8/7/2017
9-Jun-17
04/24/2017
11/09/2009
10/09/2015
10/09/2015
12/14/2012
10/09/2015
10/09/2015
10/13/2011
09/28/2010
10/13/2011
11/21/2008
10/13/2011
08/12/2010
11/06/2008
10/13/2011
10/13/2011
10/13/2011
09/28/2007
11/22/2013

05/18/2012

1143760

837149
1368527
16828287
16189961
1022396
1277705
1,280,146
011054285
1,277,538
1,282,810
009948258
009034349
00948258
006537047
009948092
1048621
006536999
009948118
009948308
009948423
005419031
1,186,977

00002531080

Status

Registered

Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered

Registered

Registered

Iceland

12/19/2013

3594/2013

11/22/2013

1,186,977

-19-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Docket Number

2542-89 Intl
2542-54 INTL
2542-55 INTL
2542-62 INTL
2542-63 INTL
2542-30 INTL
2542-89 Intl/UK  

  Client Ref No.

8251-70 MP
8251-71 MP
8251-72 MP
8251-73 MP
8251-12 MP

2542-84UK
2542-72
2542-54
2542-55
2542-70
2542-9
2542-31
2542-33
2542-32
2542-11
2542-12
2542-10
2542-30
2542-88

8251-70
8251-71

8251-14
8251-16
8251-15
8251-11
8251-13
8251-8
8251-12

Country
International
International
International
International
International
International
UK
UK
United States
United States
United States
United States
United States
United States
United States
United States
United States
United States
United States
United States
United States

   Application Date  
8/7/2017
10/09/2015
10/09/2015
10/09/2015
10/09/2015
11/22/2013
3/6/2017
06/22/2017
06/21/2016
04/10/2015
04/10/2015
06/29/2015
09/22/2003
12/29/2010
01/25/2012
12/29/2010
05/04/2009
05/04/2009
04/28/2006
08/12/2010
2/21/2017

Application No
A0069009
A0053765
1,280,146
1277538
1,282,810
A0039418
  WE00001368527  
UK00003238912
87/078,346
86/593,696
86/593,862
86/677,227
76/978,843
85/207,192
85/524,990
85/207,229
77/728,511
77/728,499
78/871,967
85/105,993
87/343,172

-20-

   Registration Date  

 Registration No.

10/09/2015
10/09/2015
10/09/2015
10/09/2015
11/22/2013
1/9/2018
09/08/2017

04/11/2017
04/11/2017
02/14/2017
08/19/2008
04/03/2012
03/04/2014
11/22/2011
10/12/2010
01/10/2012
08/05/2008
05/22/2012

1277705
1/280,146
1277538
1,282,810
1,186,977
1368527
  UK00003238912  

5,182,183
5,182,184
5,142,544
3,489,209
4,120,445
4,491,643
4,058,892
3,862,228
4,085,298
3,482,366
4,147,273

Status
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Filed
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Registered
Filed

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
None.

Copyrights

-21-

 
 
 
 
 
 
 
 
SECURITIES PURCHASE AGREEMENT

Exhibit 10.45

SECURITIES PURCHASE AGREEMENT (the “Agreement”), dated as of August 31, 2018, by and among Applied DNA Sciences, Inc., a Delaware corporation, with

headquarters located at 50 Health Sciences Drive, Stony Brook, New York 11790 (the “Company”), and the investors listed on the Schedule of Buyers attached hereto (individually,
a “Buyer” and collectively, the “Buyers”).

WHEREAS:

A.           The Company and each Buyer is executing and delivering this Agreement in reliance upon the exemption from securities registration afforded by Section 4(a)(2)

of the Securities Act of 1933, as amended (the “1933 Act”), and Rule 506(b) of Regulation D (“Regulation D”) as promulgated by the United States Securities and Exchange
Commission (the “SEC”) under the 1933 Act.

B.           The Company has authorized a new series of secured convertible notes of the Company which notes shall be convertible into the Company’s common stock,

$0.001 par value per share (the “Common Stock”), all in accordance with the terms of the Notes (as defined below).

C.           Each Buyer wishes to purchase on a several and not a joint basis, and the Company wishes to sell, upon the terms and conditions stated in this Agreement, that
principal amount of the Notes, in substantially the form attached hereto as Exhibit A (the “Notes”), set forth opposite such Buyer’s name in column (3) on the Schedule of Buyers
attached hereto (which aggregate amount for all Buyers shall be $1,650,000).

D.           Contemporaneously with the execution and delivery of this Agreement, the parties hereto are executing and delivering a Registration Rights Agreement,

substantially in the form attached hereto as Exhibit B (the “Registration Rights Agreement”), pursuant to which the Company has agreed to provide certain registration rights
with respect to the Registrable Securities (as defined in the Registration Rights Agreement) under the 1933 Act and the rules and regulations promulgated thereunder, and
applicable state securities laws.

E.           The Common Stock issued upon the conversion of the Notes shall be known as the “Conversion Shares.”

F.           The Notes and the Conversion Shares are collectively referred to herein as the “Securities.”

G.           The Notes will be secured by a security interest in substantially all of the assets of the Company, as evidenced by the security agreement, substantially in the

form attached hereto as Exhibit C (the “Security Document”), which shall be executed within five (5) Business Days of the Closing.

NOW, THEREFORE, the Company and each Buyer hereby agree as follows:

1.          PURCHASE AND SALE OF NOTES.

(a)          Purchase of Notes. Subject to the satisfaction (or waiver) of the conditions set forth in Sections 6 and 7 below, the Company shall issue and sell to each Buyer,

and each Buyer severally, but not jointly, agrees to purchase from the Company on the applicable Closing Date (as defined below), a principal amount of Notes as is set forth
opposite such Buyer’s name in column (3) on the Schedule of Buyers (the “Closing”).

(b)          Closing. The Closing shall occur on the applicable Closing Date (as defined below) at the offices of Pepper Hamilton LLP, 620 Eighth Avenue, New York, NY

10018.

(c)          Purchase Price. The purchase price for each Buyer of the Notes to be purchased by each such Buyer at the Closing shall be the amount set forth opposite such

Buyer’s name in column (4) of the Schedule of Buyers (the “Purchase Price”).

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(d)          Closing Date. The date and time of each Closing (each, a “Closing Date”) shall be mutually agreed by the Company and each Buyer after notification of

satisfaction (or waiver) of the conditions to the Closing set forth in Sections 6 and 7 below.

(e)          Delivery and Payment. On or prior to the Closing Date, each Buyer shall pay its Purchase Price for the Notes to be issued and sold to such Buyer at the Closing
by check or wire transfer of immediately available funds to such account or accounts of the Company as the Company shall specify, and the Company shall deliver to each Buyer,
the Notes (in the principal amounts as such Buyer shall request) which such Buyer is then purchasing duly executed on behalf of the Company and registered in the name of such
Buyer or its designee.

2.          BUYER’S REPRESENTATIONS AND WARRANTIES.

Each Buyer represents and warrants with respect to only itself and no other Buyer that:

(a)          No Public Sale or Distribution. Such Buyer is (i) acquiring the Notes and (ii) upon conversion of the Notes will acquire the Conversion Shares issuable upon

conversion of the Notes, for its own account and not with a view towards, or for resale in connection with, the public sale or distribution thereof, except pursuant to sales
registered or exempted under the 1933 Act. Except as previously disclosed to the Company in writing, such Buyer (i) does not presently have any agreement or understanding,
directly or indirectly, with any Person (defined as any individual, limited liability company, partnership, joint venture, corporation, trust, unincorporated organization, government
or any department or agency thereof) to distribute any of the Securities, and (ii) is not a broker-dealer registered with the SEC under the Securities Exchange Act of 1934, as
amended (the “1934 Act”), or any entity engaged in the business that would require it to be so registered as a broker-dealer.

(b)          Accredited Investor Status. Such Buyer is an “accredited investor” as that term is defined in Rule 501(a) of Regulation D.

(c)          Reliance on Exemptions. Such Buyer understands that the Securities are being offered and sold to it in reliance on specific exemptions from the registration
requirements of United States federal and state securities laws and that the Company is relying in part upon the truth and accuracy of, and such Buyer’s compliance with, the
representations, warranties, agreements, acknowledgments and understandings of such Buyer set forth herein in order to determine the availability of such exemptions and the
eligibility of such Buyer to acquire the Securities.

(d)          Information. Such Buyer and its advisors, if any, have been furnished with all materials relating to the business, finances and operations of the Company and
materials relating to the offer and sale of the Securities, which have been requested by such Buyer. Such Buyer and its advisors, if any, have reviewed a copy of the Company’s
most recent Annual Report on Form 10-K (including any risk factors), Quarterly Reports on Form 10-Q (including any risk factors), Proxy Statements on Form Def 14A and current
reports on Form 8-K. Such Buyer and its advisors, if any, have been afforded the opportunity to ask questions of the Company. Such Buyer understands that its investment in the
Securities involves a high degree of risk. Such Buyer has sought such accounting, legal and tax advice as it has considered necessary to make an informed investment decision
with respect to its acquisition of the Securities.

(e)          No Governmental Review. Such Buyer understands that no United States federal or state agency or any other government or governmental agency has passed on

or made any recommendation or endorsement of the Securities or the fairness or suitability of the investment in the Securities nor have such authorities passed upon or endorsed
the merits of the offering of the Securities. Any statement to the contrary is unlawful.

(f)          Legends. Buyer understands that the certificates or other instruments representing the Securities have been issued pursuant to an exemption from registration or
qualification under the 1933 Act and applicable state securities laws, and except as set forth below, the Securities shall bear any legend as required by the “blue sky” laws of any
state and a restrictive legend in substantially the following form (and a stop-transfer order may be placed against transfer of such stock certificates):

-2-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
NEITHER THE ISSUANCE AND SALE OF THE SECURITIES REPRESENTED BY THIS CERTIFICATE NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE

CONVERTIBLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY
NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED (I) IN THE ABSENCE OF (A) AN EFFECTIVE REGISTRATION STATEMENT FOR THE SECURITIES
UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR (B) AN OPINION OF COUNSEL TO THE HOLDER (IF REQUESTED BY THE COMPANY), IN A FORM
REASONABLY ACCEPTABLE TO THE COMPANY, THAT REGISTRATION IS NOT REQUIRED UNDER SAID ACT OR (II) UNLESS SOLD OR ELIGIBLE TO BE SOLD
PURSUANT TO RULE 144 OR RULE 144A UNDER SAID ACT.

Certificates evidencing Securities shall not be required to contain the legend set forth above or any other legend (i) while a registration statement covering the resale of

such Securities is effective under the 1933 Act, (ii) following any sale of such Securities pursuant to Rule 144 (assuming the transferor is not an affiliate of the Company), (iii) if
such Securities are eligible to be sold, assigned or transferred under Rule 144 (provided that Buyer provides the Company with reasonable assurances that such Securities are
eligible for sale, assignment or transfer under Rule 144), (iv) in connection with a sale, assignment or other transfer (other than under Rule 144), provided that Buyer provides the
Company with an opinion of counsel to Buyer from reputable counsel to the effect that such sale, assignment or transfer of the Securities may be made without registration under
the applicable requirements of the 1933 Act or (v) if such legend is not required under applicable requirements of the 1933 Act (including, without limitation, controlling judicial
interpretations and pronouncements issued by the SEC).

If a legend is not required pursuant to the foregoing, the Company shall no later than five (5) Business Days following the delivery by Buyer to the Company or the

transfer agent (with notice to the Company) of a legended certificate representing such Securities (endorsed or with stock powers attached, signatures guaranteed, and otherwise
in form necessary to affect the reissuance and/or transfer, if applicable), together with any other deliveries from Buyer as may be required above in this Section 2(f), as directed by
Buyer, either: (A) provided that the Company’s transfer agent is participating in the DTC Fast Automated Securities Transfer Program and such Securities are Conversion Shares,
credit the aggregate number of shares of Common Stock to which Buyer shall be entitled to Buyer’s or its designee’s balance account with DTC through its Deposit/Withdrawal at
Custodian system or (B) if the Company’s transfer agent is not participating in the DTC Fast Automated Securities Transfer Program or the Securities are not shares of Common
Stock, issue and deliver (via reputable overnight courier) to Buyer, a certificate representing such Securities that is free from all restrictive and other legends, registered in the name
of Buyer or its designee.

(g)          Validity; Enforcement. This Agreement, the Registration Rights Agreement and the Security Document to which such Buyer is a party have been duly and validly

authorized, executed and delivered on behalf of such Buyer and shall constitute the legal, valid and binding obligations of such Buyer enforceable against such Buyer in
accordance with their respective terms, except as such enforceability may be limited by general principles of equity or to applicable bankruptcy, insolvency, reorganization,
moratorium, liquidation or other similar laws relating to, or affecting generally, the enforcement of applicable creditors’ rights and remedies.

(h)          Residency. Such Buyer is a resident of that jurisdiction specified below its address on the Schedule of Buyers.

(i)           Brokers and Finders. No Person will have, as a result of the transactions contemplated by the Transaction Documents, as defined below, any valid right, interest
or claim against or upon the Company for any commission, fee or other compensation pursuant to any agreement, arrangement or understanding with a placement agent entered
into by or on behalf of such Buyer.

(j)           Confidentiality Prior To The Date Hereof. Other than to other Persons party to this Agreement, such Buyer has maintained the confidentiality of all disclosures

made to it in connection with this transaction (including the existence and terms of this transaction).

(k)          Sold to Various Buyers. Such Buyer understands that the Notes (i) may be sold to various Buyers in one or more Closings, (ii) will generally be for a term of three

years but may have varying maturity dates, (iii) may be purchased by officers and directors of the Company, (iv) regardless of issue or sale date, will be secured on a pari passu
basis by the same Security Document, and the perfection of any related security interest is not required to occur until 30 days after the first Closing Date and (v) may be issued in a
principal amount of up to $3,500,000. In addition, Buyer understands that a majority of the principal amount of the Notes may be purchased by the Chief Executive Officer of the
Company (the “CEO”) and as a result the CEO may have the ability to direct the actions of the Collateral Agent, direct the approval of amendments to the Transaction Documents
and control the demand rights under the Registration Rights Agreement.

-3-

 
 
 
 
 
 
 
 
 
 
 
 
(l)          No Independent Counsel. Such Buyer understands that Pepper Hamilton LLP has represented the Company in the preparation of the Transaction Documents and

there is no independent counsel that has represented the Buyers.

3.          REPRESENTATIONS AND WARRANTIES OF THE COMPANY.

The Company represents and warrants to each of the Buyers as of the date hereof that:

(a)          Organization and Qualification. The Company is duly organized and validly existing in good standing under the laws of the jurisdiction in which it is formed, and

has the requisite power and authorization to own its properties and to carry on its business as now being conducted.

(b)          Authorization; Enforcement; Validity. The Company and its Subsidiaries each has the corporate power and authority to enter into and perform its obligations

under this Agreement, the Notes, the Registration Rights Agreement, the Security Document, the Transfer Agent Instructions (substantially in the Form of Exhibit D) to which it is
a party, and each of the other agreements entered into by the parties hereto in connection with the transactions contemplated by this Agreement (collectively, the “Transaction
Documents”) and to issue the Securities in accordance with the terms hereof and thereof. The execution and delivery of the Transaction Documents by the Company and its
Subsidiaries and the consummation by the Company and its Subsidiaries of the transactions contemplated hereby and thereby, including, without limitation, the issuance of the
Notes, the reservation for issuance and the issuance of the Conversion Shares issuable upon conversion of the Notes, and the granting of a security interest in the Collateral (as
defined in the Security Document), have been duly authorized by the Company’s and such Subsidiaries’ respective Board of Directors and no further consent, or authorization is
required by the Company, such Subsidiaries, their respective Board of Directors or their respective stockholders. This Agreement and the other Transaction Documents have been
duly executed and delivered by the Company and such Subsidiaries, and constitute the legal, valid and binding obligations of the Company and such Subsidiaries, enforceable
against the Company and such Subsidiaries in accordance with their respective terms, except (i) the perfection of any security interest required by the Security Document need not
occur until 45 days after the first Closing Date and (ii) as such enforceability may be limited by general principles of equity or applicable bankruptcy, insolvency, reorganization,
moratorium, liquidation or other similar laws relating to, or affecting generally, the enforcement of applicable creditors’ rights and remedies.

(c)          Issuance of Securities. The issuance of the Notes are duly authorized and are free from all taxes, liens and charges with respect to the issue thereof. As of the

Closing, 660,000 shares of Common Stock shall have been duly authorized and reserved for issuance which equals 100% of the maximum number of shares Common Stock issuable
upon conversion of the Notes. Upon conversion in accordance with the Notes, the Conversion Shares will be validly issued, fully paid and nonassessable and free from all
preemptive or similar rights, taxes, liens and charges with respect to the issue thereof, with the holders being entitled to all rights accorded to a holder of Common Stock. Subject to
the accuracy of the representations made by each Buyer in Section 2, the offer and issuance by the Company of the Securities is exempt from registration under the 1933 Act.

(d)          No Conflicts. The execution, delivery and performance of the Transaction Documents by the Company and its Subsidiaries and the consummation by the

Company and its Subsidiaries of the transactions contemplated hereby and thereby (including, without limitation, the issuance of the Notes, the granting of a security interest in
the Collateral and reservation for issuance and issuance of the Conversion Shares) will not (i) result in a violation of the Certificate of Incorporation of the Company, as amended
from time to time and as in effect on the date hereof (the “Certificate of Incorporation”) or any certificate or articles of incorporation, certificate of formation, any certificate of
designations or other charter document of any of its Subsidiaries, or the Bylaws of the Company, as amended from time to time and as in effect on the date hereof (the “Bylaws”),
or any of its Subsidiaries or (ii) conflict with, or constitute a default (or an event which with notice or lapse of time or both would become a default) under, or give to others any
rights of termination, amendment, acceleration or cancellation of, any agreement, indenture or instrument to which the Company or any of its Subsidiaries is a party, or (iii) result in
a violation of any law, rule, regulation, order, judgment or decree (including federal and state securities laws and regulations and the rules and regulations of The NASDAQ Capital
Market (the “Principal Market”)) applicable to the Company or any of its Subsidiaries or by which any property or asset of the Company or any of its Subsidiaries is bound or
affected, except in the case of clauses (ii) and (iii) above, for such conflicts, defaults, rights or violations that would not, individually or in the aggregate, have a Material Adverse
Effect. As used in this Agreement, “Material Adverse Effect” means any material adverse effect on the business, properties, assets, operations, results of operations, condition
(financial or otherwise) or prospects of the Company and its Subsidiaries, taken as a whole, or on the transactions contemplated by this Agreement and the other Transaction
Documents, or on the authority or ability of the Company to perform its obligations under the Transaction Documents.

-4-

 
 
 
 
 
 
 
 
 
 
 
(e)          Consents. Except for the filing with the SEC of one or more Registration Statements in accordance with the requirements of the Registration Rights Agreement, the
filing with the SEC of a Current Report on Form 8-K describing the terms of the transactions contemplated by the Transaction Documents, the filing of the Form D with the SEC and
for such filings as shall be required under state securities or “blue sky” laws, and the filing of any notice with the Financial Industry Regulatory Authority, neither the Company
nor any of its Subsidiaries is required to obtain any consent, authorization or order of, or make any filing or registration with, any court, governmental agency or any regulatory or
self-regulatory agency or any other Person in order for it to execute, deliver or perform any of its obligations under or contemplated by the Transaction Documents, in each case in
accordance with the terms hereof or thereof, which have not been or will not be obtained or effected on or prior to the Closing Date, and the Company and its Subsidiaries have no
knowledge of any facts or circumstances which might prevent the Company from obtaining or effecting any of the registration, application or filings pursuant to the preceding
sentence.

4.          COVENANTS.

(a)          Reasonable Best Efforts. Each party shall use its reasonable best efforts timely to satisfy each of the covenants and conditions to be satisfied by it as provided in

Sections 6 and 7 of this Agreement.

(b)          Disclosure of Transactions and Other Material Information. On or before 8:30 a.m., New York City time, by the fourth (4th) Business Day following the date of this
Agreement, the Company shall file a Current Report on Form 8-K describing the terms of the transactions contemplated by the Transaction Documents in the form required by the
1934 Act and attaching the material Transaction Documents (including, without limitation, this Agreement (and all schedules to this Agreement), the form of the Notes, the
Registration Rights Agreement and the Security Document) as exhibits to such filing (including all attachments, the “8-K Filing”). As used herein, “Business Day” means any day
other than Saturday, Sunday or other day on which commercial banks in The City of New York are authorized or required by law to remain closed.

(c)          Reservation of Shares. So long as any Buyer owns any Securities, the Company shall take all action necessary to at all times have authorized, and reserved for the

purpose of issuance, no less than 100% of the number of shares of Common Stock issuable upon conversion of the Notes then outstanding (without taking into account any
limitations on the conversion of the Notes set forth in the Notes).

(d)          Collateral Agent.

(i)          Corporation Service Company (“CSC”) is hereby appointed Collateral Agent under the Security Document and each Buyer hereby authorizes CSC, in
such capacity, to act as its agent in accordance with the terms of the Security Document and this Agreement. The provisions of this Section 4(d) are solely for the benefit of the
Buyers and the Company and its Affiliates shall not have any rights as a third party beneficiary of any of the provisions thereof. In performing its functions and duties under the
Security Document and this Agreement, the Collateral Agent shall act solely as an agent of Buyers and does not assume and shall not be deemed to have assumed any obligation
towards or relationship of agency or trust with the Company or any of its Affiliates. The Collateral Agent shall be obligated, and shall have the powers and rights, to make
demands, to give notices, to exercise or refrain from exercising any rights, and to take or refrain from taking any action (including, without limitation, the release or substitution of
Collateral), solely in accordance with this Agreement and the Security Document. If any provision, duty, obligation or right under the Security Document is in conflict with any
provision, duty, obligation or right under this Agreement then this Agreement shall control. The Collateral Agent shall not have any duties or responsibilities, except those
expressly set forth herein and in the Security Document and such powers as are incidental thereto.

-5-

 
 
 
 
 
 
 
 
 
 
 
(ii)         Each Buyer irrevocably authorizes the Collateral Agent to take such action on such Buyer’s behalf and to exercise such powers, rights and remedies

hereunder as are specifically delegated or granted to the Collateral Agent by the terms of this Agreement and the Security Document, together with such powers, rights and
remedies as are reasonably incidental thereto. The Collateral Agent shall have only those duties and responsibilities that are expressly specified herein and therein. The Collateral
Agent may exercise such powers, rights and remedies and perform such duties by or through its agents or employees. Notwithstanding any other provisions hereof or of any
provision of the Security Document, the Collateral Agent shall not have or be deemed to have any fiduciary relationship with the Buyers or any other person or entity, and no
implied covenants, functions, responsibilities, duties, obligations or liabilities shall be read into this Agreement or the Security Document or otherwise exist against the Collateral
Agent. Without limiting the generality of the foregoing sentence, the use of the term “agent” in this Agreement or the Security Document with reference to the Collateral Agent is
not intended to connote any fiduciary or other implied (or express) obligations arising under agency doctrine of any applicable law.

(iii)        The Collateral Agent may act in reliance upon any writing or instrument or signature which it, in good faith, believes to be genuine, and may assume the

validity and accuracy of any statement or assertion contained in such a writing or instrument and may assume that any person or entity purporting to give any writing, notice,
advice or instruction in connection with the provisions hereof has been duly authorized to do so. The Collateral Agent may consult with counsel and shall be entitled to act, and
shall be fully protected in any action taken in good faith, in accordance with advice given by counsel. The Collateral Agent shall not be liable to the Company or any of its
Affiliates, or the Buyers for any recitals or warranties herein or in the Security Document, nor for the effectiveness, enforceability, validity or due execution of the Security
Document or any other agreement, document or instrument, nor to make any inquiry respecting the performance by any party of their respective obligations thereunder. Any such
inquiry which may be made by the Collateral Agent shall not obligate it to make any further inquiry or to take any action.

(iv)        The Collateral Agent shall not be required to take any action which, in the Collateral Agent’s sole and absolute judgment, could involve it in expense or

liability unless furnished with security and indemnity which it deems, in its sole and absolute discretion, to be satisfactory. In the event the Collateral Agent receives conflicting
instructions hereunder or under any of the Security Document, the Collateral Agent shall be fully protected in refraining from acting until such conflict is resolved to the
satisfaction of the Collateral Agent. Neither the Collateral Agent nor any of its directors, officers, employees or agents shall be liable, except for the Collateral Agent’s bad faith,
negligence or willful misconduct as finally determined by a court of competent jurisdiction for any action taken or omitted under or in connection with this Agreement, the Security
Document or any other instrument or document in connection herewith or therewith.

(v)         The Collateral Agent may resign or be removed by the Buyers (by a vote of the holders of a majority of the outstanding principal of the Notes) as

Collateral Agent hereunder at any time upon at least thirty (30) days’ prior notice. If the Collateral Agent at any time shall resign, the Buyers shall (by a vote of the holders of a
majority of the outstanding principal of the Notes), within ten (10) days after such notice appoint a successor Collateral Agent which shall thereupon become the Collateral Agent
hereunder and under the Security Document. If no successor Collateral Agent shall have been so appointed, and shall have accepted such appointment, within the above time
frame the retiring Collateral Agent may appoint a successor. Upon the acceptance of any appointment as Collateral Agent hereunder by a successor Collateral Agent, such
successor Collateral Agent shall be entitled to receive from the retiring Collateral Agent such documents of transfer and assignment as such successor Collateral Agent may
reasonably request, and shall thereupon succeed to and become vested with all rights, powers, privileges and duties of the retiring Collateral Agent, and the retiring Collateral
Agent shall be discharged from its duties and obligations under this Agreement. After the effective date of any retiring Collateral Agent’s resignation hereunder as collateral agent,
the provisions of this section shall inure to its benefit as to any actions taken or omitted to be taken by it while it was Collateral Agent under this Agreement.

(vi)        The Collateral Agent shall not be deemed to have knowledge or notice of the occurrence of any default unless the Collateral Agent has received a copy

of a notice thereof from a Buyer referring to this Agreement and describing such default. In the event that the Collateral Agent receives such a notice, the Collateral Agent shall
promptly give notice thereof to the other Buyers and to the Company. The Collateral Agent shall be permitted to take such action with respect to any default as provided in this
Agreement and the Security Document.

-6-

 
 
 
 
 
 
 
 
 
(vii)       Each Buyer, by its acceptance of the benefits hereof and of the Security Document, agrees that it shall have no right individually to realize upon any of

the Collateral, it being understood and agreed by each Buyer that all rights and remedies may be exercised solely by the Collateral Agent for the benefit of the Buyer in accordance
with the provisions of this Agreement and the Security Document in the Collateral Agent’s sole and absolute discretion.

(viii)      Upon any payment or distribution of assets of the Company of any kind or character, whether in cash, property or securities, to its creditors upon any

dissolution or winding-up or total or partial liquidation or reorganization of the Company, whether voluntary or involuntary or in bankruptcy, insolvency, receivership or other
proceedings including, without limitation, all amounts received by the Collateral Agent on behalf of the Buyers, or received by the Buyers, shall be paid by the in accordance with
its outstanding secured Obligations (as defined in the Security Document) to each of the Buyers in accordance with clause (xii) below. Any and all amounts referred to in this
clause (viii)or any other amounts or proceeds of collateral received by any of the Buyers shall be held in trust for the benefit of all of the Buyers, shall be immediately delivered by
the applicable Buyers to the Collateral Agent in the amount and form received, and shall be apportioned, paid over or delivered among the Buyers in accordance with clause (xi) of
this Agreement.

(ix)         Except as provided by law, the security interests in the Collateral shall be for the ratable benefit of the Buyers, shall rank equally in priority, none being

senior or subordinate to any other. No Buyer shall contest the validity, perfection, priority or enforceability of the lien of any other Buyer in the Collateral. Each Buyer, by its
acceptance of the benefits hereof, agrees that it shall have no right individually to realize upon any of the Collateral under this Agreement, the Security Document, pursuant to
applicable law, or otherwise, it being understood and agreed by each Buyer that all rights and remedies under this Agreement, the Security Document, pursuant to applicable law,
or otherwise, may be exercised solely by the Collateral Agent for the benefit of Buyers in accordance with the provisions of this Agreement and the Security Document.

(x)          Upon any payment or distribution of assets of the Company of any kind or character, whether in cash, property or securities, to creditors upon any
dissolution or winding-up or total or partial liquidation or reorganization of the Company, whether voluntary or involuntary or in bankruptcy, insolvency, receivership or other
proceedings (each such payment, distribution and/or amount is hereafter referred to as a “Collateral Proceeds Amount”), shall be disbursed in accordance with clause (xi) below.

(xi)         Any and all Collateral Proceeds Amount and any other amounts or proceeds of Collateral received by any of the Buyers shall be held in trust for the

benefit of all of the Buyers, shall be immediately delivered by the applicable Buyer to the Collateral Agent in the amount and form received, and, subject to the rights to any of the
Collateral Proceeds Amount or such other amounts or proceeds of Collateral of the holders of the other security interests in the Collateral referred to in clause (x) above, shall be
apportioned, paid over or delivered as follows: first, to the Collateral Agent for the payment or reimbursement of any expenses and fees of, or any other amount payable to, the
Collateral Agent hereunder or under the Security Document, and next, among the Buyers on a pro rata basis to each in accordance with the Company’s outstanding obligations to
each of the Buyers which are secured pursuant to this Agreement.

5.          REGISTER; TRANSFER AGENT INSTRUCTIONS.

(a)          Register. The Company shall maintain at its principal executive offices (or such other office or agency of the Company as it may designate by notice to each
holder of Securities), a register for the Notes in which the Company shall record the name and address of the Person in whose name the Notes have been issued (including the
name and address of each transferee), the aggregate number of Notes held by such Person, and any tax related information required to be maintained. The Company shall keep the
register open and available at all times during business hours for inspection of any Buyer or its legal representatives.

(b)          Transfer Agent Instructions. If a Buyer effects a sale, assignment or transfer of the Conversion Shares, the Company shall permit the transfer, in compliance with

applicable securities laws, and shall promptly instruct its transfer agent to issue one or more certificates or credit shares to the applicable balance accounts at DTC in such name
and in such denominations as specified by such Buyer to effect such sale, transfer or assignment. In the event that such sale, assignment or transfer involves Conversion Shares
sold, assigned or transferred pursuant to an effective registration statement or in compliance with Rule 144, the transfer agent shall issue such shares to such Buyer, assignee or
transferee (as the case may be) without any restrictive legend in accordance with Section 2(f). Any fees (with respect to the transfer agent, counsel to the Company or otherwise)
associated with the issuance of such opinion or the removal of any legends on any of the Securities as referred to in Section 2(f) shall be borne by the Company.

-7-

 
 
 
 
 
 
 
 
 
 
 
 
6.          CONDITIONS TO THE COMPANY’S OBLIGATION TO SELL.

The obligation of the Company hereunder to issue and sell the Notes to each Buyer at the Closing is subject to the satisfaction, at or before the Closing Date, of each of

the following conditions, provided that these conditions are for the Company’s sole benefit and may be waived by the Company at any time in its sole discretion by providing each
Buyer with prior written notice thereof:

(i)          Such Buyer and each other Buyer shall have executed each of the Transaction Documents to which it is a party and delivered the same to the Company.

(ii)         Such Buyer and each other Buyer shall have delivered to the Company the Purchase Price for the Notes being purchased by such Buyer and each other

Buyer at the Closing by check or wire transfer of immediately available funds.

(iii)        The representations and warranties of such Buyer and each other Buyer shall be true and correct in all material respects as of the date hereof and as of

the Closing Date as though made at that time (except for representations and warranties that speak as of a specific date), and such Buyer and each other Buyer shall have
performed, satisfied and complied in all material respects with the covenants, agreements and conditions required by this Agreement to be performed, satisfied or complied with by
such Buyer and each other Buyer at or prior to the Closing Date.

7.          CONDITIONS TO EACH BUYER’S OBLIGATION TO PURCHASE.

The obligation of each Buyer hereunder to purchase the Notes at the Closing is subject to the satisfaction, at or before the Closing Date, of each of the following

conditions, provided that these conditions are for each Buyer’s sole benefit and may be waived by such Buyer at any time in its sole discretion by providing the Company with
prior written notice thereof:

(i)          The Company shall have executed and delivered to such Buyer (A) each of the Transaction Documents and (B) the Notes (in such principal amounts as

such Buyer shall request) being purchased by such Buyer at the Closing pursuant to this Agreement.

(ii)         The Company shall have delivered to such Buyer a copy of the Transfer Agent Instructions, substantially in the form attached hereto as Exhibit D, which

instructions shall have been delivered to and acknowledged in writing by the Company’s transfer agent.

(iii)        The representations and warranties of the Company shall be true and correct in all material respects (except for those representations and warranties that
are qualified by materiality or Material Adverse Effect, which shall be true and correct in all respects) as of the date when made and as of the Closing Date as though made at that
time (except for representations and warranties that speak as of a specific date) and the Company shall have performed, satisfied and complied in all material respects with the
covenants, agreements and conditions required by the Transaction Documents to be performed, satisfied or complied with by the Company at or prior to the Closing Date.

(iv)        The Common Stock (I) shall be designated for quotation or listed on the Principal Market and (II) shall not have been suspended, as of the Closing Date,

by the SEC or the Principal Market from trading on the Principal Market nor shall suspension by the SEC or the Principal Market have been threatened, as of the Closing Date.

(v)         The Company shall have obtained all governmental, regulatory or third party consents and approvals, if any, necessary for the sale of the Securities.

-8-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
8.          TERMINATION. In the event that the Closing shall not have occurred with respect to a Buyer on or before ten (10) Business Days from the date hereof due to the
Company’s or such Buyer’s failure to satisfy the conditions set forth in Sections 6 and 7 above (and the nonbreaching party’s failure to waive such unsatisfied condition(s)), the
nonbreaching party shall have the option to terminate this Agreement at the close of business on such date without liability of any party to any other party.

9.          MISCELLANEOUS.

(a)          Governing Law; Jurisdiction; Jury Trial. All questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be governed

by the internal laws of the State of New York, without giving effect to any choice of law or conflict of law provision or rule (whether of the State of New York or any other
jurisdictions) that would cause the application of the laws of any jurisdictions other than the State of New York. Each party hereby irrevocably submits to the exclusive jurisdiction
of the state and federal courts sitting in The City of New York, Borough of Manhattan, for the adjudication of any dispute hereunder or in connection herewith or with any
transaction contemplated hereby or discussed herein, and hereby irrevocably waives, and agrees not to assert in any suit, action or proceeding, any claim that it is not personally
subject to the jurisdiction of any such court, that such suit, action or proceeding is brought in an inconvenient forum or that the venue of such suit, action or proceeding is
improper. Each party hereby irrevocably waives personal service of process and consents to process being served in any such suit, action or proceeding by mailing a copy thereof
to such party at the address for such notices to it under this Agreement and agrees that such service shall constitute good and sufficient service of process and notice thereof.
Nothing contained herein shall be deemed to limit in any way any right to serve process in any manner permitted by law. EACH PARTY HEREBY IRREVOCABLY WAIVES ANY
RIGHT IT MAY HAVE, AND AGREES NOT TO REQUEST, A JURY TRIAL FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR IN CONNECTION WITH OR
ARISING OUT OF THIS AGREEMENT OR ANY TRANSACTION CONTEMPLATED HEREBY.

(b)          Counterparts. This Agreement may be executed in two or more identical counterparts, all of which shall be considered one and the same agreement and shall

become effective when counterparts have been signed by each party and delivered to the other party; provided that a facsimile signature shall be considered due execution and
shall be binding upon the signatory thereto with the same force and effect as if the signature were an original, not a facsimile signature.

(c)          Headings. The headings of this Agreement are for convenience of reference and shall not form part of, or affect the interpretation of, this Agreement.

(d)          Severability. If any provision of this Agreement shall be invalid or unenforceable in any jurisdiction, such invalidity or unenforceability shall not affect the
validity or enforceability of the remainder of this Agreement in that jurisdiction or the validity or enforceability of any provision of this Agreement in any other jurisdiction.

(e)          Entire Agreement; Amendments. This Agreement and the other Transaction Documents supersede all other prior oral or written agreements between the Buyers,

the Company, their affiliates and Persons acting on their behalf with respect to the matters discussed herein, and this Agreement, the other Transaction Documents and the
instruments referenced herein and therein contain the entire understanding of the parties with respect to the matters covered herein and therein and, except as specifically set forth
herein or therein, neither the Company nor any Buyer makes any representation, warranty, covenant or undertaking with respect to such matters. No provision of this Agreement
may be amended other than by an instrument in writing signed by the Company and the Required Holders (as defined in the Note), and any amendment to this Agreement made in
conformity with the provisions of this Section 9(e) shall be binding on all Buyers and holders of Securities, as applicable. No provision hereof may be waived other than by an
instrument in writing signed by the party against whom enforcement is sought. No such amendment shall be effective to the extent that it applies to less than all of the holders of
the applicable Securities then outstanding. No consideration shall be offered or paid to any Person to amend or consent to a waiver or modification of any provision of any of the
Transaction Documents unless the same consideration also is offered to all of the parties to the Transaction Documents or holders of Notes. The Company has not, directly or
indirectly, made any agreements with any Buyers relating to the terms or conditions of the transactions contemplated by the Transaction Documents except as set forth in the
Transaction Documents. Without limiting the foregoing, the Company confirms that, except as set forth in this Agreement, no Buyer has made any commitment or promise or has
any other obligation to provide any financing to the Company or otherwise.

-9-

 
 
 
 
 
 
 
 
 
 
 
(f)          Notices. Any notices, consents, waivers or other communications required or permitted to be given under the terms of this Agreement must be in writing and will
be deemed to have been delivered: (i) upon receipt, when delivered personally; (ii) upon receipt, when sent by facsimile (provided confirmation of transmission is mechanically or
electronically generated and kept on file by the sending party); or (iii) one Business Day after deposit with an overnight courier service, in each case properly addressed to the
party to receive the same. The addresses and facsimile numbers for such communications shall be:

If to the Company:

Applied DNA Sciences, Inc.
50 Health Sciences Drive
Stony Brook, New York 11790
Telephone:
Attention:

(631) 240-8800
Chief Financial Officer

With copies to:

Pepper Hamilton LLP
620 Eighth Street, Floor 37
New York, NY 10018
Telephone:
Attention:

212-808-2724
Merrill Kraines, Esq.

If to the Transfer Agent:

American Stock Transfer and Trust Company
6201 15th Ave.
Brooklyn, New York 11219
Telephone: (718) 921-8210
Facsimile: (718) 921-8355
Attention: Vito Cirone

If to the Collateral Agent:
CSC
251 Little Falls Drive
Wilmington, DE 19808
Telephone: (866) 403-5272
Facsimile: (302) 636-5454
Attention: [●]

If to a Buyer, to its address and facsimile number set forth on the Schedule of Buyers, with copies to such Buyer’s representatives as set forth on the Schedule of Buyers, or to
such other address and/or facsimile number and/or to the attention of such other Person as the recipient party has specified by written notice given to each other party five (5)
days prior to the effectiveness of such change. Written confirmation of receipt (A) given by the recipient of such notice, consent, waiver or other communication, (B) mechanically
or electronically generated by the sender’s facsimile machine containing the time, date, recipient facsimile number and an image of the first page of such transmission or (C)
provided by an overnight courier service shall be rebuttable evidence of personal service, receipt by facsimile or receipt from an overnight courier service in accordance with clause
(i), (ii) or (iii) above, respectively.

-10-

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(g)          Successors and Assigns. This Agreement shall be binding upon and inure to the benefit of the parties and their respective successors and assigns, including any
purchasers of the Notes. The Company shall not assign this Agreement or any rights or obligations hereunder without the prior written consent of the Required Holders, including
by way of a Fundamental Transaction (unless the Company is in compliance with the applicable provisions governing Fundamental Transactions set forth in the Notes). A Buyer
may assign some or all of its rights hereunder without the consent of, but upon prompt written notice to, the Company, in which event such assignee shall be deemed to be a Buyer
hereunder with respect to such assigned rights.

(h)          No Third Party Beneficiaries. This Agreement is intended for the benefit of the parties hereto and their respective permitted successors and assigns, and is not for

the benefit of, nor may any provision hereof be enforced by, any other Person.

(i)          Reliance by the Collateral Agent. The parties agree and acknowledge that the Collateral Agent may rely on the representations, warranties, agreements and

covenants of the Company contained in this Agreement and may rely on the representations and warranties to the respective Buyer set forth in this Agreement as if such
representations, warranties, agreements and covenants, as applicable, were made directly to the Collateral Agent. In addition, no representation, warranty or covenant, express or
implied, is or will be made by the Collateral Agent with respect to the Company or the transactions contemplated by this Agreement; and no responsibility of any kind exists with
the Collateral Agent with respect to the completeness or accuracy of, or any other matter concerning, any other information made or provided by the Company or its
representatives to the Buyer (as to diligence matters or otherwise) or with respect to any statements made regarding any such information by the Company, its representatives or
the Collateral Agent to the Buyers.

(j)          Survival. Unless this Agreement is terminated under Section 8, the representations and warranties of the Company and the Buyers contained in Sections 2 and 3
and the agreements and covenants set forth in Sections 4, 5 and 9 shall survive the Closing for a period of one (1) year from the date hereof. Each Buyer shall be responsible only
for its own representations, warranties, agreements and covenants hereunder.

(k)          Further Assurances. Each party shall do and perform, or cause to be done and performed, all such further acts and things, and shall execute and deliver all such

other agreements, certificates, instruments and documents, as any other party may reasonably request in order to carry out the intent and accomplish the purposes of this
Agreement and the consummation of the transactions contemplated hereby.

(l)          No Strict Construction. The language used in this Agreement will be deemed to be the language chosen by the parties to express their mutual intent, and no rules

of strict construction will be applied against any party.

(m)          Remedies. Each Buyer and each holder of the Securities shall have all rights and remedies set forth in the Transaction Documents and all rights and remedies
which such holders have been granted at any time under any other agreement or contract and all of the rights which such holders have under any law. Any Person having any
rights under any provision of this Agreement shall be entitled to enforce such rights specifically (without posting a bond or other security), to recover damages by reason of any
breach of any provision of this Agreement and to exercise all other rights granted by law. Furthermore, the Company recognizes that in the event that it fails to perform, observe, or
discharge any or all of its obligations under the Transaction Documents, any remedy at law may prove to be inadequate relief to the Buyers. The Company therefore agrees that the
Buyers shall be entitled to seek temporary and permanent injunctive relief in any such case without the necessity of proving actual damages and without posting a bond or other
security.

(n)          Rescission and Withdrawal Right. Notwithstanding anything to the contrary contained in (and without limiting any similar provisions of) the Transaction

Documents, whenever any Buyer exercises a right, election, demand or option under a Transaction Document and the Company does not timely perform its related obligations
within the periods therein provided, then such Buyer may rescind or withdraw, in its sole discretion from time to time upon written notice to the Company, any relevant notice,
demand or election in whole or in part without prejudice to its future actions and rights.

 
 
 
 
 
 
 
 
 
 
 
(o)          Payment Set Aside. To the extent that the Company makes a payment or payments to the Buyers hereunder or pursuant to any of the other Transaction

Documents or the Buyers enforce or exercise their rights hereunder or thereunder, and such payment or payments or the proceeds of such enforcement or exercise or any part
thereof are subsequently invalidated, declared to be fraudulent or preferential, set aside, recovered from, disgorged by or are required to be refunded, repaid or otherwise restored
to the Company, a trustee, receiver or any other Person under any law (including, without limitation, any bankruptcy law, foreign, state or federal law, common law or equitable
cause of action), then to the extent of any such restoration the obligation or part thereof originally intended to be satisfied shall be revived and continued in full force and effect as
if such payment had not been made or such enforcement or setoff had not occurred.

(p)          Independent Nature of Buyers’ Obligations and Rights. The obligations of each Buyer under any Transaction Document are several and not joint with the
obligations of any other Buyer, and no Buyer shall be responsible in any way for the performance of the obligations of any other Buyer under any Transaction Document. Nothing
contained herein or in any other Transaction Document, and no action taken by any Buyer pursuant hereto or thereto, shall be deemed to constitute the Buyers as a partnership,
an association, a joint venture or any other kind of entity, or create a presumption that the Buyers are in any way acting in concert or as a group with respect to such obligations or
the transactions contemplated by the Transaction Documents and the Company acknowledges that the Buyers are not acting in concert or as a group with respect to such
obligations or the transactions contemplated by the Transaction Documents. Each Buyer confirms that it has independently participated in the negotiation of the transaction
contemplated. Each Buyer shall be entitled to independently protect and enforce its rights, including, without limitation, the rights arising out of this Agreement or out of any other
Transaction Documents, and it shall not be necessary for any other Buyer to be joined as an additional party in any proceeding for such purpose.

[Signature Page Follows]

-11-

 
  
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

COMPANY:

APPLIED DNA SCIENCES, INC.

By:

/s/ Beth Jantzen
Name: Beth Jantzen
Title: Chief Financial Officer

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:

By:

/s/ James A. Hayward
Name: James A. Hayward
Title:

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:

By:

/s/ Judith Murrah
Name: Judith Murrah
Title: Chief Information Officer

Applied DNA Sciences, Inc.

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:
Delabarta II

By:

/s/ John F. Bitzer III
Name: John F. Bitzer III
Title: President

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:

By:

/s/ Yacov Shamash
Name: Yacov Shamash
Title:

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:

By:

/s/ Robert Catell
Name:
Title:

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:

By:

/s/ Elizabeth Schmalz Ferguson
Name:
Title:

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:
The Rodgers Living Trust Dated April 7, 1995

By:

/s/ Jay D. Rodgers
Name: Jay D. Rodgers
Title: Trustee

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:

By:

/s/ Gregg Baldwin
Name: W. Gregg Baldwin
Title:

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:

By:

/s/ William W. Montgomery 8/30/2018
Name: William W. Montgomery
Title: (private investor)
Mr. William W. Montgomery
34211 Seavey Loop Rd.
Eugene, OR 97405

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:

By:

/s/ Johnette van Eeden
Name: Johnette van Eeden
Title:

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Securities Purchase Agreement to be duly executed as of the

date first written above.

Each Buyer hereby attests to receipt and review of the following documents:

1) Purchase Agreement (including all exhibits and schedules)

Attestation of Receipt of Documents

2) Registration Rights Agreement

3) Security Agreement

4) Form of Note

BUYERS:

By:

/s/ John Cartier
Name: John Cartier
Title:

[Signature Page to Securities Purchase Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(1)

Buyer

James A. Hayward

Judith Murrah

Delabarta II

Yavoc Shamash

Robert Catell

Elizabeth Schmalz Ferguson
The Rodgers Living Trust Dated April 7,
1995

Gregg Baldwin

William Montgomery

Johnette van Eeden

John Cartier

SCHEDULE OF BUYERS

(2)

Address and
Facsimile Number

(3)
Aggregate
Principal
Amount of
Notes

(4)

(5)

Purchase
Price

Legal Representative’s
Address and
Facsimile Number

1 Emmet Dr 
Stony Brook, NY 11790
8 Old Post La 
Saint James, NY 11780
c/o Delaware Corporate Management 
1105 North Market Street 
Suite 1300 
Wilmington, DE 19801
7 Quaker Hill Rd 
Stony Brook, NY 11790
62 Osborne Rd 
Garden City, NY 11530
101 Jersey Ave 
Spring Lake, NJ 07762
1277 Porter Rd 
Flower Mound, TX 75022
3391 Ichabod Way 
The Villages, FL 32163
34211 Seavey Loop Rd 
Eugene, OR 97405
451 Westpark Way, Ste 5 
Euless, TX 76040
PO Box ____ 
East Hampton, NY 11937

  $

1,000,000    $

25,000    $

100,000    $

25,000    $

25,000    $

10,000    $

100,000    $

50,000    $

200,000    $

100,000    $

15,000    $

2.50   

2.50     

2.50     

2.50     

2.50     

2.50     

2.50     

2.50     

2.50     

2.50     

2.50     

 
 
 
 
   
   
   
 
   
     
     
 
 
 
 
   
  
 
   
  
 
   
  
 
   
  
 
   
  
 
   
  
 
   
  
 
   
  
 
   
  
 
   
  
 
 
Exhibit A
Exhibit B
Exhibit C
Exhibit D

Form of Notes
Registration Rights Agreement
Form of Security Agreement of the Company
Transfer Agent Instructions

EXHIBITS

 
 
 
 
 
Exhibit A

Form of Notes

 
 
 
 
 
[FORM OF SECURED CONVERTIBLE NOTE]

NEITHER  THE  ISSUANCE AND  SALE  OF  THE  SECURITIES  REPRESENTED  BY  THIS  CERTIFICATE  NOR  THE  SECURITIES  INTO  WHICH  THESE  SECURITIES ARE
CONVERTIBLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES
MAY  NOT  BE  OFFERED  FOR  SALE,  SOLD,  TRANSFERRED  OR ASSIGNED  (I)  IN  THE ABSENCE  OF  (A) AN  EFFECTIVE  REGISTRATION  STATEMENT  FOR  THE
SECURITIES  UNDER  THE  SECURITIES  ACT  OF  1933,  AS  AMENDED,  OR  (B)  AN  OPINION  OF  COUNSEL,  IN  A  GENERALLY  ACCEPTABLE  FORM,  THAT
REGISTRATION IS NOT REQUIRED UNDER SAID ACT OR (II) UNLESS SOLD PURSUANT TO RULE 144 OR RULE 144A UNDER SAID ACT. ANY TRANSFEREE OF
THIS  NOTE  SHOULD  CAREFULLY  REVIEW  THE  TERMS  OF  THIS  NOTE,  INCLUDING  SECTIONS  3(c)(ii)  AND  17(a)  HEREOF.  THE  PRINCIPAL  AMOUNT
REPRESENTED BY THIS NOTE AND, ACCORDINGLY, THE SECURITIES ISSUABLE UPON CONVERSION HEREOF MAY BE LESS THAN THE AMOUNTS SET FORTH
ON THE FACE HEREOF PURSUANT TO SECTION 3(c)(ii) OF THIS NOTE.

Applied DNA Sciences, Inc.

Secured Convertible Note

Issuance Date: August 31, 2018

Original Principal Amount: U.S. $___________
Interest Rate per Annum: 6.00%

FOR  VALUE  RECEIVED, Applied  DNA  Sciences,  Inc.,  a  Delaware  corporation  (the  “Company”),  hereby  promises  to  pay  to  [___________________]  or
registered  assigns  (“Holder”)  the  amount  set  out  above  as  the  Original  Principal Amount  (as  reduced  pursuant  to  the  terms  hereof  pursuant  to  redemption,  conversion  or
otherwise, the “Principal”) when due, whether upon the Maturity Date (as defined below), acceleration, redemption or otherwise (in each case in accordance with the terms hereof)
and to pay interest (“Interest”) on any outstanding Principal at the applicable Interest Rate from the date set out above as the Issuance Date (the “Issuance Date”) until the same
becomes due and payable, whether upon an Interest Date (as defined below), the Maturity Date, acceleration, redemption, conversion or otherwise (in each case in accordance
with the terms hereof). This Secured Convertible Note (including all Secured Convertible Notes issued in exchange, transfer or replacement hereof, this “Note”) is one of an issue of
Secured Convertible Notes issued pursuant to the Securities Purchase Agreement on multiple Closing Dates (collectively, the “ Notes” and such other Secured Convertible Notes,
the “Other Notes”). Certain capitalized terms used herein are defined in Section 26.

1 .           PAYMENTS OF PRINCIPAL . Subject to the conversion of the Principal and accrued and unpaid Interest (as defined below) into Conversion Shares
pursuant to Section 8 hereof, on the Maturity Date, the Company shall pay to the Holder an amount in cash representing all outstanding Principal, accrued and unpaid Interest.
The “Maturity Date” shall be August 30, 2021. At any time the Company may prepay any portion or all of the outstanding Principal amount of this Note and any accrued and
unpaid Interest.

2.           INTEREST; INTEREST RATE.

(a)          Interest on this Note shall commence accruing on the Issuance Date and shall be computed on the basis of a 360-day year comprised of twelve
thirty day months and shall be payable in arrears semi-annually on February 28th and August 31st during the period beginning on the Issuance Date and ending on, and including,
the Maturity Date or the Conversion Date, as the case may be (the “Interest Date”). Subject to the conversion of the accrued and unpaid Interest into Conversion Shares pursuant
to Section 8 hereof, Interest shall be payable on the Interest Date to the record holder of this Note on the Interest Date, in cash.

(b)          From and after the occurrence and during the continuance of an Event of Default, the Interest Rate shall be increased to 10% per annum, or the
maximum rate permissible by law, whichever is less. In the event that such Event of Default is subsequently cured, the adjustment referred to in the preceding sentence shall cease
to be effective as of the date of such cure; provided that the Interest as calculated and unpaid at such increased rate during the continuance of such Event of Default shall
continue to apply to the extent relating to the days after the occurrence of such Event of Default through and including the date of cure of such Event of Default.

Exhibit A-1

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(c)          Notwithstanding any provision in this Note to the contrary, through the Maturity Date, at the option of the Company in lieu of paying in cash
the interest accrued to any Interest Date, any accrued but unpaid interest shall be capitalized and added as of such Interest Date to the principal amount of this Note (the “PIK
Amount”). Such PIK Amount shall bear interest from the applicable Interest Date at the same rate per annum and be payable in the same manner as in the case of the original
principal amount of this Note and shall otherwise be treated as principal of this Note for all purposes. From and after each Interest Date, the principal amount of this Note shall,
including with respect to Conversion Amount, without further action on the part of the Company or the Holder, be deemed to be increased by the PIK Amount so capitalized and
added to principal in accordance with the provisions hereof.

3.           CONVERSION OF NOTES. This Note shall be convertible into Conversion Shares, on the terms and conditions set forth in this Section 3.

(a)          Conversion Right. At any time or times on or after the Issuance Date, the Holder shall be entitled to convert any portion of the outstanding and
unpaid Conversion Amount (as defined below) into fully paid and nonassessable Conversion Shares in accordance with Section 3(c), at the Conversion Rate (as defined below).
The Company shall not issue any fraction of a Conversion Share upon any conversion. If the issuance would result in the issuance of a fraction of a Conversion Share, the
Company shall round such fraction of a Conversion Share up to the nearest whole share. The Company shall pay any and all transfer, stamp and similar taxes that may be payable
with respect to the issuance and delivery of Conversion Shares upon conversion of any Conversion Amount; provided that the Company shall not be required to pay any tax that
may be payable in respect of the issuance and delivery of Conversion Shares to any Person other than the Holder or with respect to any income tax due by the Holder with respect
to such Conversion Shares.

determined by dividing (x) such Conversion Amount by (y) the Conversion Price (the “Conversion Rate”).

( b )          Conversion Rate. The number of Conversion Shares issuable upon conversion of any Conversion Amount pursuant to Section 3(a) shall be

determination is being made, plus all accrued and unpaid Interest on any Conversion Amount up to and including the Conversion Date (as defined below).

(i)                    “Conversion Amount”  means  the  portion  of  the  Principal  to  be  converted,  redeemed  or  otherwise  with  respect  to  which  this

(ii)         “Conversion Price” means USD $2.50.

(c)          Mechanics of Conversion.

(i)          Optional Conversion. To convert any Conversion Amount into Conversion Shares on any date (a “Conversion Date”), the Holder shall
(A) transmit by facsimile or email (by attachment in PDF format) (or otherwise deliver), for receipt on or prior to 11:59 p.m., New York Time, on such date, a copy of an executed
notice of conversion in the form attached hereto as Exhibit I (the “Conversion Notice”) to the Company and (B) if required by Section 3(c)(ii), surrender this Note to a common
carrier for delivery to the Company as soon as practicable on or following such date (or an indemnification undertaking with respect to this Note in the case of its loss, theft or
destruction). On or before the first Business Day following the date of receipt of a Conversion Notice, the Company shall transmit by facsimile or email (by attachment in PDF
format) a confirmation (the “Conversion Confirmation”) of receipt of such Conversion Notice to the Holder and the Company’s Transfer Agent. Any Conversion Confirmation
delivered by the Company shall confirm the Conversion Amount. On or before the fifth Business Day following the date of receipt of a Conversion Notice, the Company shall,
provided that the Transfer Agent is participating in the DTC Fast Automated Securities Transfer Program, credit such aggregate number of Conversion Shares to which the Holder
shall be entitled to the Holder’s or its designee’s balance account with DTC through its Deposit/Withdrawal as Custodian system. If the Transfer Agent is not participating in the
DTC  Fast Automated  Securities  Transfer  Program or if a  Holder otherwise requests, the  Company shall issue and deliver (via reputable overnight courier) to the address as
specified in the Conversion Notice, a certificate, registered in the name of the Holder or its designee, for the number of Conversion Shares to which the Holder shall be entitled. If
this Note is physically surrendered for conversion as required by Section 3(c)(ii) and the outstanding Principal of this Note is greater than the Principal portion of the Conversion
Amount being converted, then the Company shall as soon as practicable and in no event later than five Business Days after receipt of this Note and at its own expense, issue and
deliver to the holder a new Note (in accordance with Section 17(d)) representing the outstanding Principal not converted. The Person or Persons entitled to receive the Conversion
Shares issuable upon a conversion of this Note shall be treated for all purposes as the record holder or holders of such Conversion Shares on the Conversion Date.

Exhibit A-2

 
 
 
 
 
 
 
 
 
 
 
 
(ii)         Registration; Book-Entry. The Company shall maintain a register (the “Register”) for the recordation of the names and addresses of the
holders of each Note and the principal amount of the Notes held by such holders (the “Registered Notes”). The entries in the Register shall be conclusive and binding for all
purposes absent manifest error. The Company and the holders of the Notes shall treat each Person whose name is recorded in the Register as the owner of a Note for all purposes,
including, without limitation, the right to receive payments of principal and interest hereunder, notwithstanding notice to the contrary. A Registered Note may be assigned or sold
in whole or in part only by registration of such assignment or sale on the Register. Upon its receipt of a request to assign or sell all or part of any Registered Note by a Holder, the
Company shall record the information contained therein in the Register and issue one or more new Registered Notes in the same aggregate principal amount as the principal
amount of the surrendered Registered Note to the designated assignee or transferee pursuant to Section 17. Notwithstanding anything to the contrary set forth herein, upon
conversion of any portion of this Note in accordance with the terms hereof, the Holder shall not be required to physically surrender this Note to the Company unless (A) the full
Principal amount represented by this Note is being converted or (B) the Holder has provided the Company with prior written notice (which notice may be included in a Conversion
Notice) requesting reissuance of this Note upon physical surrender of this Note. The Holder and the Company shall maintain records showing the Principal and Interest converted
and the dates of such conversions or shall use such other method, reasonably satisfactory to the Holder and the Company, so as not to require physical surrender of this Note
upon conversion.

4.           RIGHTS UPON EVENT OF DEFAULT.

(a)          Event of Default. Each of the following events shall constitute an “Event of Default:”

Days or for more than an aggregate of ten Trading Days in any 365-day period;

(i)          the suspension from trading or failure of the Common Stock to be listed on an Eligible Market for a period of five consecutive Trading

(ii)         the delisting of the Company’s Common Stock from the Principal Market;

(iii)        the Company’s failure to pay to the Holder any amount of Principal, Interest, or other amounts when and as due under this Note or any
other Transaction Document (as defined in the Securities Purchase Agreement) or any other agreement, document, certificate or other instrument delivered in connection with the
transactions contemplated hereby and thereby to which the Holder is a party, except, in the case of a failure to pay Interest and other amounts when and as due, in which case only
if such failure continues for a period of at least three Business Days;

(iv)        the Company or any of its Subsidiaries, pursuant to or within the meaning of Title 11, U.S. Code, or any similar Federal, foreign or state
law for the relief of debtors (collectively, “Bankruptcy Law”), (A) commences a voluntary case, (B) consents to the entry of an order for relief against it in an involuntary case, (C)
consents to the appointment of a receiver, trustee, assignee, liquidator or similar official (a “Custodian”), (D) makes a general assignment for the benefit of its creditors or (E) admits
in writing that it is generally unable to pay its debts as they become due;

(v)         any proceeding is instituted against the Company or any of its Subsidiaries in an involuntary case, or a court of competent jurisdiction
enters an order or decree under any Bankruptcy Law that (A) appoints a Custodian of the Company or any of its Subsidiaries for all or substantially all of its property or (B) orders
the liquidation of the Company or any of its Subsidiaries and, in each case, such order or decree is not dismissed or stayed within thirty days of such entry;

its part to be performed or observed and such failure shall remain unremedied for a period of ten Business Days;

(vi)        the Company shall fail to perform or observe any covenant, agreement or other obligation contained in any Transaction Document on

(vii)       the Security Agreement shall, for any reason, after the perfection date specified in the Securities Purchase Agreement, cease to create a
valid, enforceable and perfected first priority security interest and Lien in any of the Collateral (as defined in the Security Agreement) purported to be covered thereby, or the
Company shall so state in writing, or the Company shall in any way challenge, or shall bring any proceeding which shall in any way challenge, the prior valid, enforceable or
perfected status of such security interest or Lien or the validity or enforceability thereof;

(b)          Remedies. Upon the occurrence of an Event of Default, the Company shall within five Business Days deliver written notice thereof via facsimile
or email and overnight courier (an “Event of Default Notice”) to the Holder. At any time after the earlier of the Holder’s receipt of an Event of Default Notice and the Holder
becoming aware of an Event of Default, the Holder may require the Company to redeem all or any portion of this Note by delivering written notice thereof (the “Event of Default
Redemption Notice”) to the Company, which Event of Default Redemption Notice shall indicate the portion of this Note the Holder is electing to redeem and, in the case the Holder
has not received an  Event of  Default  Notice, the  Event of  Default of which the  Holder has become aware.  Each portion of this  Note subject to redemption by the  Company
pursuant to this Section 4(b) shall be redeemed by the Company at a price equal to the sum of the Conversion Amount to be redeemed together with accrued and unpaid Interest
with respect to such Conversion Amount (the “Event of Default Redemption Price”). Redemptions required by this Section 4(b) shall be made in accordance with the provisions of
Section 12. To the extent redemptions required by this Section 4(b) are deemed or determined by a court of competent jurisdiction to be prepayments of the Note by the Company,
such redemptions shall be deemed to be voluntary prepayments. The parties hereto agree that in the event of the Company’s redemption of any portion of the Note under this
Section 4(b), the Holder’s damages would be uncertain and difficult to estimate because of the parties’ inability to predict future interest rates and the uncertainty of the availability
of a suitable substitute investment opportunity for the Holder.

Exhibit A-3

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
5.           RIGHTS UPON FUNDAMENTAL TRANSACTION; CHANGE OF CONTROL.

(a )          Assumption. The Company shall not enter into or be party to a Fundamental Transaction unless the Successor Entity assumes in writing all of
the obligations of the Company under this Note and the other Transaction Documents in accordance with the provisions of this Section 5(a) pursuant to written agreements in
form and substance reasonably satisfactory to the Required Holders and approved by the Required Holders prior to such Fundamental Transaction, including agreements to
deliver to each holder of Notes in exchange for such Notes a security of the Successor Entity evidenced by a written instrument substantially similar in form and substance to the
Notes, including, without limitation, having a principal amount and interest rate equal to the principal amounts and the interest rates of the Notes then outstanding held by such
holder, having similar conversion rights and having similar ranking to the Notes, and satisfactory to the Required Holders. Upon the occurrence of any Fundamental Transaction,
the  Successor  Entity shall succeed to, and be substituted for (so that from and after the date of such  Fundamental  Transaction, the provisions of this  Note referring to the
“Company” shall refer instead to the Successor Entity), and may exercise every right and power of the Company and shall assume all of the obligations of the Company under this
Note with the same effect as if such Successor Entity had been named as the Company herein. Upon consummation of the Fundamental Transaction, the Successor Entity shall
deliver to the Holder confirmation that there shall be issued upon conversion or redemption of this Note at any time after the consummation of the Fundamental Transaction, in lieu
of  the  shares  of  the  Company’s  Common  Stock  (or  other  securities,  cash,  assets  or  other  property)  issuable  upon  the  conversion  or  redemption  of  the  Notes  prior  to  such
Fundamental Transaction, such shares of the publicly traded common stock (or their equivalent) of the Successor Entity (including its Parent Entity), as adjusted in accordance
with the provisions of this Note. The provisions of this Section 5 shall apply similarly and equally to successive Fundamental Transactions and shall be applied without regard to
any limitations on the conversion or redemption of this Note.

( b )          Redemption Right. No sooner than fifteen days nor later than ten days prior to the consummation of a Change of Control, but not prior to the
public announcement of such Change of Control, the Company shall deliver written notice thereof via facsimile or email and overnight courier to the Holder (a “Change of Control
Notice”). At any time during the period beginning after the Holder’s receipt of a Change of Control Notice and ending twenty Trading Days after the date of the consummation of
such Change of Control, the Holder may require the Company to redeem all or any portion of this Note by delivering written notice thereof (“Change of  Control  Redemption
Notice”) to the Company, which Change of Control Redemption Notice shall indicate the Conversion Amount the Holder is electing to redeem. The portion of this Note subject to
redemption pursuant to this Section 5 shall be redeemed by the Company in cash at a price equal to the Conversion Amount being redeemed plus any accrued and unpaid interest
on  the  Conversion Amount  being  redeemed  (the  “Change  of  Control  Redemption  Price”).  Redemptions  required  by  this  Section  5(b)  shall  be  made  in  accordance  with  the
provisions of Section 12. To the extent redemptions required by this Section 5(b) are deemed or determined by a court of competent jurisdiction to be prepayments of the Note by
the Company, such redemptions shall be deemed to be voluntary prepayments. The parties hereto agree that in the event of the Company’s redemption of any portion of the Note
under this Section 5(b), the Holder’s damages would be uncertain and difficult to estimate because of the parties’ inability to predict future interest rates and the uncertainty of the
availability of a suitable substitute investment opportunity for the Holder.

6.           RIGHTS UPON ISSUANCE OF PURCHASE RIGHTS AND OTHER CORPORATE EVENTS.

( a )          Purchase Rights. If at any time the Company grants, issues or sells any Options, Convertible Securities or rights to purchase stock, warrants,
securities or other property pro rata to the record holders of any class of Common Stock (the “Purchase Rights”), then the Holder will be entitled to acquire, upon the terms
applicable to such Purchase Rights, the aggregate Purchase Rights which the Holder could have acquired if the Holder had held the number of shares of Common Stock acquirable
upon complete conversion of this Note (without taking into account any limitations or restrictions on the convertibility of this Note) immediately before the date on which a record
is taken for the grant, issuance or sale of such Purchase Rights, or, if no such record is taken, the date as of which the record holders of Common Stock are to be determined for the
grant, issue or sale of such Purchase Rights.

Exhibit A-4

 
  
 
 
 
 
 
 
 
( b )          Other Corporate Events. In addition to and not in substitution for any other rights hereunder, prior to the consummation of any Fundamental
Transaction pursuant to which holders of shares of Common Stock are entitled to receive securities or other assets with respect to or in exchange for shares of Common Stock (a
“Corporate Event”), the Company shall make appropriate provision to insure that the Holder will thereafter have the right to receive upon a conversion of this Note, at the Holder’s
option, (i) in addition to the Conversion Shares receivable upon such conversion, such securities or other assets to which the Holder would have been entitled with respect to
such Conversion Shares had such Conversion Shares been held by the Holder upon the consummation of such Corporate Event (without taking into account any limitations or
restrictions on the convertibility of this Note) or (ii) in lieu of the Conversion Shares otherwise receivable upon such conversion, such securities or other assets received by the
holders of shares of Common Stock in connection with the consummation of such Corporate Event in such amounts as the Holder would have been entitled to receive had this
Note  initially  been  issued  with  conversion  rights  for  the  form  of  such  consideration  (as  opposed  to  shares  of  Common  Stock)  at  a  conversion  rate  for  such  consideration
commensurate with the Conversion Rate. Provision made pursuant to the preceding sentence shall be in a form and substance satisfactory to the Required Holders. The provisions
of this Section 6 shall apply similarly and equally to successive Corporate Events and shall be applied without regard to any limitations on the conversion or redemption of this
Note.

7.           RIGHTS UPON ISSUANCE OF OTHER SECURITIES.

( a )          Stock Dividends and Stock Splits. If the Company, at any time while this Note is outstanding (A) pays a stock dividend or otherwise makes a
distribution or distributions on shares of its Common Stock or any other equity or equity equivalent securities payable in shares of Common Stock (which, for avoidance of doubt,
shall not include any shares of Common Stock issued by the Company pursuant to this Note), or (B) subdivides (by any stock split, stock dividend, recapitalization or otherwise)
one or more classes of its outstanding shares of Common Stock into a greater number of shares, the Conversion Price in effect immediately prior to such subdivision will be
proportionately  reduced.  If  the  Company  at  any  time  while  this  Note  is  outstanding:  combines  (by  combination,  reverse  stock  split  or  otherwise)  one  or  more  classes  of  its
outstanding  shares  of  Common  Stock  as  the  case  may  be,  into  a  smaller  number  of  shares,  the  Conversion  Price  in  effect  immediately  prior  to  such  combination  will  be
proportionately modified.

( b )          Other Events. If any event occurs of the type contemplated by the provisions of this Section 7 but not expressly provided for by such
provisions  (including,  without  limitation,  the  granting  of  stock  appreciation  rights,  phantom  stock  rights  or  other  rights  with  equity  features),  then  the  Company’s  Board  of
Directors will make an appropriate adjustment in the Conversion Price so as to protect the rights of the Holder under this Note; provided that no such adjustment will increase the
Conversion Price as otherwise determined pursuant to this Section 7.

8.           COMPANY’S RIGHT OF MANDATORY CONVERSION.

( a )          Mandatory Conversion. If the price of the Company’s Common Stock shall remain at a closing price of $3.50 or more for a period of twenty
consecutive Trading Days, the Company shall have the right to require the Holder to convert all, or any part, of the Conversion Amount of this Note into fully paid, validly issued
and nonassessable shares of Common Stock in accordance with Section 3(c) hereof at the Conversion Rate with respect to the Conversion Amount (the “Mandatory Conversion”).
The mechanics of conversion set forth in Section 3(c) shall apply to any Mandatory Conversion as if the Company and the Transfer Agent had received from the Holder on the
Mandatory Conversion Date a Conversion Notice with respect to the Conversion Amount being converted pursuant to the Mandatory Conversion.

9.           SECURITY. This Note and the Other Notes are secured to the extent, within the time and in the manner set forth in the Security Documents (as defined in

the Securities Purchase Agreement).

1 0 .         NONCIRCUMVENTION. The Company hereby covenants and agrees that the Company will not, by amendment of its Certificate of Incorporation,
Bylaws or through any reorganization, transfer of assets, consolidation, merger, scheme of arrangement, dissolution, issue or sale of securities, or any other voluntary action, avoid
or seek to avoid the observance or performance of any of the terms of this Note, and will at all times in good faith carry out all of the provisions of this Note and take all reasonable
action as may be required to protect the rights of the Holder of this Note.

11.         RESERVATION OF AUTHORIZED SHARES.

( a )          Reservation. The Company shall reserve out of its authorized and unissued stock a number of shares of Common Stock or other securities
issuable upon conversion of the Notes, as the case may be, for each of the Notes equal to 100% of the Conversion Rate with respect to the Conversion Amount of each such Note
as of the Issuance Date (such applicable amount, the “Required Reserve Amount”). The Company shall increase the Required Reserved Amount in proportion to any increase in
the outstanding principal amount of the Note resulting from a PIK amount.

Exhibit A-5

 
 
 
 
 
 
 
 
 
 
 
 
 
 
( b )          Insufficient Authorized Shares . If at any time while any of the Notes remain outstanding the Company does not have a sufficient number of
authorized and unreserved shares of Common Stock or other securities issuable upon conversion of the Notes, as the case may be, to satisfy its obligation to reserve for issuance
upon conversion of the Notes at least a number of shares of Common Stock or other securities issuable upon conversion of the Notes, as the case may be, equal to the Required
Reserve Amount (an “Authorized Share Failure”), then the Company shall immediately take all action necessary to increase the Company’s authorized shares of Common Stock or
other securities issuable upon conversion of the Notes, as the case may be, to an amount sufficient to allow the Company to reserve the Required Reserve Amount for the Notes
then outstanding. Without limiting the generality of the foregoing sentence, as soon as reasonably practicable after the date of the occurrence of an Authorized Share Failure, but
in no event later than sixty days after the occurrence of such Authorized Share Failure, the Company shall hold a meeting of its stockholders for the approval of an increase in the
number of authorized shares of Common Stock or, if required by applicable law, other securities issuable upon conversion of the Notes, as the case may be. In connection with
such meeting, the Company shall provide each stockholder with a proxy statement and shall use its reasonable efforts to solicit its stockholders’ approval of such increase in
authorized shares of Common Stock or, if required by applicable law, other securities issuable upon conversion of the Note, as the case may be, and to cause its board of directors
of the Company to recommend to the stockholders that they approve such proposal.

12.         HOLDER’S REDEMPTIONS.

(a )          Mechanics. The Company shall deliver the applicable Event of Default Redemption Price or the Change of Control Redemption Price (together,
the  “Redemption  Price”)  to  the  Holder  within  five  Business  Days  after  the  Company’s  receipt  of  the  Holder’s  Event  of  Default  Redemption  Notice  or  Change  of  Control
Redemption Notice (together, the “Redemption Notice”). In the event of a redemption of less than all of the Conversion Amount of this Note, the Company shall promptly cause to
be issued and delivered to the Holder a new Note (in accordance with Section 17(d)) representing the outstanding Principal which has not been redeemed. In the event that the
Company does not pay the applicable Redemption Price to the Holder within the time period required, at any time thereafter and until the Company pays such unpaid Redemption
Price in full, the Holder shall have the option, in lieu of redemption, to require the Company to promptly return to the Holder all or any portion of this Note representing the
Conversion Amount that was submitted for redemption and for which the applicable Redemption Price has not been paid. Upon the Company’s receipt of such notice, (x) the
applicable Redemption Notice shall be null and void with respect to such Conversion Amount, and (y) the Company shall immediately return this Note, or issue a new Note (in
accordance with Section 17(d)) to the Holder representing the sum of such Conversion Amount to be redeemed together with accrued and unpaid Interest with respect to such
Conversion Amount.

( b )          Redemption by Other Holders. Upon the Company’s receipt of notice from any of the holders of the Other Notes for redemption or repayment
as a result of an event or occurrence substantially similar to the events or occurrences described in Section 4(b), the Company shall immediately, but no later than one Business
Day of its receipt thereof, forward to the Holder by facsimile or email a copy of such notice.

13.         VOTING RIGHTS. The Holder shall have no voting rights as the holder of this Note, except as required by law, including, but not limited to, the Delaware

General Corporation Law, and as expressly provided in this Note.

14.         COVENANTS. So long as this Note is outstanding:

(a)          Rank. All payments due under this Note shall rank pari passu with all Other Notes.

Bylaws without the prior written consent of the Required Holders (which consent shall not be unreasonably withheld).

( b )          Certificate of Incorporation and Bylaws. Except as set forth in Section 11(b), the Company shall not amend its Certificate of Incorporation or

(c)          Use of Proceeds.  The Company will use the proceeds from the sale of the Notes for general working capital purposes.

15.         VOTE TO ISSUE, OR CHANGE THE TERMS OF, NOTES. The affirmative vote of the Required Holders at a meeting duly called for such purpose or the
written consent without a meeting shall be required for any change or amendment to this Note or the Other Notes. In no event shall any amendment, modification or waiver be
made to this Note which would adversely effect the Holder without the written consent of the Holder.

1 6 .         TRANSFER. This Note and any Conversion Shares issued upon conversion of this Note may be offered, sold, assigned or transferred by the Holder

without the consent of the Company, subject only to the provisions of Section 2(f) of the Securities Purchase Agreement and applicable securities laws.

Exhibit A-6

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
17.         REISSUANCE OF THIS NOTE.

(a)          Transfer. If this Note is to be transferred, the Holder shall surrender this Note to the Company, whereupon the Company will forthwith issue and
deliver upon the order of the Holder a new Note (in accordance with Sections 16 and 17(d)), registered as the Holder may request, representing the outstanding Principal being
transferred by the Holder and, if less than the entire outstanding Principal is being transferred, a new Note (in accordance with Section 17(d)) to the Holder representing the
outstanding Principal not being transferred. The Holder and any assignee, by acceptance of this Note, acknowledge and agree that, by reason of the provisions of Section 3(c)(ii)
following conversion or redemption of any portion of this Note, the outstanding Principal represented by this Note may be less than the Principal stated on the face of this Note.

( b )          Lost,  Stolen  or  Mutilated  Note.  Upon  receipt  by  the  Company  of  evidence  reasonably  satisfactory  to  the  Company  of  the  loss,  theft,
destruction or mutilation of this Note, and, in the case of loss, theft or destruction, of any indemnification undertaking by the Holder to the Company in customary form and, in the
case of mutilation, upon surrender and cancellation of this Note, the Company shall execute and deliver to the Holder a new Note (in accordance with Section 17(d)) representing
the outstanding Principal.

( c )          Note Exchangeable for Different Denominations. This Note is exchangeable, upon the surrender hereof by the Holder at the principal office of
the  Company,  for  a  new  Note  or  Notes  representing  in  the  aggregate  the  outstanding  Principal  of  this  Note,  and  each  such  new  Note  will  represent  such  portion  of  such
outstanding Principal as is designated by the Holder at the time of such surrender.

(d)          Issuance of New Notes. Whenever the Company is required to issue a new Note pursuant to the terms of this Note, such new Note (i) shall be
of like tenor with this Note, (ii) shall represent, as indicated on the face of such new Note, the Principal remaining outstanding (or in the case of a new Note being issued pursuant
to Section 17(a) or Section 17(c), the Principal designated by the Holder which, when added to the principal represented by the other new Notes issued in connection with such
issuance, does not exceed the Principal remaining outstanding under this Note immediately prior to such issuance of new Notes), (iii) shall have an issuance date, as indicated on
the face of such new Note, which is the same as the Issuance Date of this Note, (iv) shall have the same rights and conditions as this Note, and (v) shall represent accrued and
unpaid Interest on the Principal and Interest of this Note, from the Issuance Date.

18.         Remedies, Characterizations, Other Obligations, Breaches And Injunctive Relief. The remedies provided in this Note shall be cumulative and in addition
to all other remedies available under this Note and any of the other Transaction Documents at law or in equity (including a decree of specific performance and/or other injunctive
relief), and nothing herein shall limit the Holder’s right to pursue actual and consequential damages for any failure by the Company to comply with the terms of this Note. Amounts
set forth or provided for herein with respect to payments, conversion and the like (and the computation thereof) shall be the amounts to be received by the Holder and shall not,
except as expressly provided herein, be subject to any other obligation of the  Company (or the performance thereof).  The  Company acknowledges that a breach by it of its
obligations hereunder will cause irreparable harm to the Holder and that the remedy at law for any such breach may be inadequate. The Company therefore agrees that, in the event
of any such breach or threatened breach, the Holder shall be entitled, in addition to all other available remedies, to an injunction restraining any breach, without the necessity of
showing economic loss and without any bond or other security being required.

19.         PAYMENT OF COLLECTION, ENFORCEMENT AND OTHER COSTS . If (a) this Note is placed in the hands of an attorney for collection or enforcement
or is collected or enforced through any legal proceeding or the Holder otherwise takes action to collect amounts due under this Note or to enforce the provisions of this Note or (b)
there occurs any bankruptcy, reorganization, receivership of the Company or other proceedings affecting Company creditors’ rights and involving a claim under this Note, then the
Company  shall  pay  the  costs  incurred  by  the  Holder  for  such  collection,  enforcement  or  action  or  in  connection  with  such  bankruptcy,  reorganization,  receivership  or  other
proceeding, including, but not limited to, attorneys’ fees and disbursements.

2 0 .         CONSTRUCTION; HEADINGS. This Note shall be deemed to be jointly drafted by the Company and all the holders of the Notes and shall not be

construed against any person as the drafter hereof. The headings of this Note are for convenience of reference and shall not form part of, or affect the interpretation of, this Note.

21.         FAILURE OR INDULGENCE NOT WAIVER. No failure or delay on the part of the Holder in the exercise of any power, right or privilege hereunder shall
operate as a waiver thereof, nor shall any single or partial exercise of any such power, right or privilege preclude other or further exercise thereof or of any other right, power or
privilege.

Exhibit A-7

 
 
 
 
 
 
 
 
 
 
 
 
 
22.         NOTICES; PAYMENTS.

( a )          Notices. Whenever notice is required to be given under this Note, unless otherwise provided herein, such notice shall be given in accordance
with Section 9(f) of the Securities Purchase Agreement. The Company shall provide the Holder with prompt written notice of all actions taken pursuant to this Note, including in
reasonable detail a description of such action and the reason therefore. Without limiting the generality of the foregoing, the Company will give written notice to the Holder (i)
immediately upon any adjustment of the Conversion Price, setting forth in reasonable detail, and certifying, the calculation of such adjustment and (ii) at least twenty days prior to
the date on which the Company closes its books or takes a record (A) with respect to any dividend or distribution upon the Common Stock, (B) with respect to any pro rata
subscription offer to holders of Common Stock or (C) for determining rights to vote with respect to any Fundamental Transaction, dissolution or liquidation, provided in each case
that such information shall be made known to the public prior to or in conjunction with such notice being provided to the Holder.

(b)          Payments. Whenever any payment of cash is to be made by the Company to any Person pursuant to this Note, such payment shall be made in
lawful money of the  United  States of America by a check drawn on the account of the  Company  and  sent  via  overnight  courier  service  to  such  Person  at  such  address  as
previously provided to the Company in writing (which address, in the case of each of the holders of the Notes, shall initially be as set forth on the Schedule of Buyers attached to
the Securities Purchase Agreement); provided that the Holder may elect to receive a payment of cash via wire transfer of immediately available funds by providing the Company
with prior written notice setting out such request and the Holder’s wire transfer instructions. Whenever any amount expressed to be due by the terms of this Note is due on any
day which is not a Business Day, the same shall instead be due on the next succeeding day which is a Business Day and, in the case of any Interest Date which is not the date on
which this Note is paid in full, the extension of the due date thereof shall not be taken into account for purposes of determining the amount of Interest due on such date. Any
amount of Principal or other amounts due under the Transaction Documents, other than Interest, which is not paid when due shall result in a late charge being incurred and
payable by the Company in an amount equal to interest on such amount at the rate of fifteen percent (15%) per annum, or the maximum rate permissible by law, which is less, from
the date such amount was due until the same is paid in full (“Late Charge”).

automatically be deemed canceled, shall be surrendered to the Company for cancellation and shall not be reissued.

2 3 .         CANCELLATION. After  all  Principal,  accrued  Interest  and  other  amounts  at  any  time  owed  on  this  Note  have  been  paid  in  full,  this  Note  shall

2 4 .         WAIVER OF NOTICE. To the extent permitted by law, the Company hereby waives demand, notice, protest and all other demands and notices in

connection with the delivery, acceptance, performance, default or enforcement of this Note and the Securities Purchase Agreement.

25.         GOVERNING LAW. This Note shall be construed and enforced in accordance with, and all questions concerning the construction, validity, interpretation
and performance of this Note shall be governed by, the internal laws of the State of New York, without giving effect to any choice of law or conflict of law provision or rule
(whether of the State of New York or any other jurisdictions) that would cause the application of the laws of any jurisdictions other than the State of New York. The Company
hereby irrevocably submits to the exclusive jurisdiction of the state and federal courts sitting in The City of New York, Borough of Manhattan, for the adjudication of any dispute
hereunder or in connection herewith or with any transaction contemplated hereby or discussed herein, and hereby irrevocably waives, and agrees not to assert in any suit, action
or proceeding, any claim that it is not personally subject to the jurisdiction of any such court, that such suit, action or proceeding is brought in an inconvenient forum or that the
venue of such suit, action or proceeding is improper. Nothing contained herein shall be deemed to limit in any way any right to serve process in any manner permitted by law. In
the event that any provision of this Note is invalid or unenforceable under any applicable statute or rule of law, then such provision shall be deemed inoperative to the extent that
it may conflict therewith and shall be deemed modified to conform with such statute or rule of law. Any such provision which may prove invalid or unenforceable under any law
shall not affect the validity or enforceability of any other provision of this Note. Nothing contained herein shall be deemed or operate to preclude the Holder from bringing suit or
taking other legal action against the Company in any other jurisdiction to collect on the Company’s obligations to the Holder, to realize on any collateral or any other security for
such obligations, or to enforce a judgment or other court ruling in favor of the Holder. THE COMPANY HEREBY IRREVOCABLY WAIVES ANY RIGHT IT MAY HAVE, AND
AGREES NOT TO REQUEST, A JURY TRIAL FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR IN CONNECTION WITH OR ARISING OUT OF THIS NOTE
OR ANY TRANSACTION CONTEMPLATED HEREBY.

Exhibit A-8

 
 
 
 
 
 
 
 
 
 
26.         CERTAIN DEFINITIONS. For purposes of this Note, the following terms shall have the following meanings:

(a)           “Bloomberg” means Bloomberg Financial Markets.

or required by law to remain closed.

(b)          “Business Day” means any day other than Saturday, Sunday or other day on which commercial banks in The City of New York are authorized

(c)          “Change of Control” means any Fundamental Transaction other than (i) any reorganization, recapitalization or reclassification of the Common
Stock  in  which  holders  of  the  Company’s  voting  power  immediately  prior  to  such  reorganization,  recapitalization  or  reclassification  continue  after  such  reorganization,
recapitalization or reclassification to hold publicly traded securities and, directly or indirectly, the voting power of the surviving entity or entities necessary to elect a majority of
the members of the board of directors (or their equivalent if other than a corporation) of such entity or entities, or (ii) pursuant to a migratory merger effected solely for the purpose
of changing the jurisdiction of incorporation of the Company.

(d)          “Closing Bid Price” and “Closing Sale Price” means, for any security as of any date, the last closing bid price and last closing trade price,
respectively, for such security on the Principal Market, as reported by Bloomberg, or, if the Principal Market begins to operate on an extended hours basis and does not designate
the closing bid price or the closing trade price, as the case may be, then the last bid price or last trade price, respectively, of such security prior to 4:00:00 p.m., New York Time, as
reported  by  Bloomberg,  or,  if  the  Principal  Market  is  not  the  principal  securities  exchange  or  trading  market  for  such  security,  the  last  closing  bid  price  or  last  trade  price,
respectively, of such security on the principal securities exchange or trading market where such security is listed or traded as reported by Bloomberg, or if the foregoing do not
apply, the last closing bid price or last trade price, respectively, of such security in the over-the-counter market on the electronic bulletin board for such security as reported by
Bloomberg, or, if no closing bid price or last trade price, respectively, is reported for such security by Bloomberg, the average of the bid prices, or the ask prices, respectively, of
any market makers for such security as reported in the “pink sheets” by Pink Sheets LLC (formerly the National Quotation Bureau, Inc.). If the Closing Bid Price or the Closing Sale
Price cannot be calculated for a security on a particular date on any of the foregoing bases, the Closing Bid Price or the Closing Sale Price, as the case may be, of such security on
such date shall be the fair market value as mutually determined by the Company and the Holder. All such determinations shall be appropriately adjusted for any stock dividend,
stock split, stock combination or other similar transaction during the applicable calculation period.

Notes were initially issued pursuant to the terms of the Securities Purchase Agreement.

(e)          “Closing Date” shall have the meaning set forth in the Securities Purchase Agreement which corresponds to the date this Note and the Other

(f)          “Common Stock” means shares of the Company’s common stock, $0.001 par value per share.

(g)          “Contingent Obligation” means, as to any Person, any direct or indirect liability, contingent or otherwise, of that Person with respect to any
indebtedness, lease, dividend or other obligation of another Person if the primary purpose or intent of the Person incurring such liability, or the primary effect thereof, is to provide
assurance to the obligee of such liability that such liability will be paid or discharged, or that any agreements relating thereto will be complied with, or that the holders of such
liability will be protected (in whole or in part) against loss with respect thereto.

exchangeable for Common Stock.

(h)                    “Convertible  Securities”  means  any  stock  or  securities  (other  than  Options)  directly  or  indirectly  convertible  into  or  exercisable  or

(i)          “Conversion Shares” means, shares of Common Stock issuable upon conversion of this Note.

Nasdaq Global Market, The Nasdaq Capital Market, or any market that is a successor to any of the foregoing.

(j)          “Eligible Market” means the Principal Market, The New York Stock Exchange, Inc., the NYSE Amex, The Nasdaq Global Select Market, The

(k)          “Fundamental Transaction” means that the Company shall, directly or indirectly, in one or more related transactions, (i) consolidate or merge
with or into (whether or not the Company is the surviving corporation) another Person or Persons, or (ii) sell, assign, transfer, convey or otherwise dispose of all or substantially all
of the properties or assets of the Company to another Person, or (iii) allow another Person (other than the Holder) to make a purchase, tender or exchange offer that is accepted by
the holders of more than 50% of the outstanding shares of Voting Stock (not including any shares of Voting Stock held by the Person or Persons making or party to, or associated
or  affiliated  with  the  Persons  making  or  party  to,  such  purchase,  tender  or  exchange  offer),  or  (iv)  consummate  a  stock  purchase  agreement  or  other  business  combination
(including, without limitation, a reorganization, recapitalization, spin-off or scheme of arrangement) with another Person whereby such other Person acquires more than the 50% of
the outstanding shares of Voting Stock (not including any shares of Voting Stock held by the other Person or other Persons making or party to, or associated or affiliated with the
other Persons making or party to, such stock purchase agreement or other business combination), or (v) reorganize, recapitalize or reclassify its Common Stock or (vi) any “person”
or “group” (as these terms are used for purposes of Sections 13(d) and 14(d) of the Exchange Act) is or shall become the “beneficial owner” (as defined in Rule 13d-3 under the
Exchange Act), directly or indirectly, of 50% of the aggregate Voting Stock of the Company.

Exhibit A-9

 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(l)          “GAAP” means United States generally accepted accounting principles, consistently applied.

(m)         “Interest Rate” means, 6.00% per annum, subject to adjustment as set forth in Section 2(b) hereof.

(n)          “Options” means any rights, warrants or options to subscribe for or purchase shares of Common Stock or Convertible Securities.

(o)          “Parent Entity” of a Person means an entity that, directly or indirectly, controls the applicable Person and whose common stock or equivalent
equity security is quoted or listed on an Eligible Market, or, if there is more than one such Person or Parent Entity, the Person or Parent Entity with the largest public market
capitalization as of the date of consummation of the Fundamental Transaction.

any other entity and a government or any department or agency thereof.

(p)           “Person” means an individual, a limited liability company, a partnership, a joint venture, a corporation, a trust, an unincorporated organization,

(q)          “Principal Market” means the NASDAQ Capital Market.

outstanding.

(r)                      “Required  Holders”  means  the  holders  of  Notes  representing  at  least  a  majority  of  the  aggregate  principal  amount  of  the  Notes  then

(s)          “SEC” means the United States Securities and Exchange Commission.

Company and the initial holders of the Notes pursuant to which the Company issued the Notes.

(t)          “Securities Purchase Agreement” means that certain securities purchase agreement dated as of the Subscription Date by and among the

(u)           “Subscription Date” means August 31, 2018.

(v)         “Successor Entity” means the Person, which may be the Company, formed by, resulting from or surviving any Fundamental Transaction or the
Person with which such Fundamental Transaction shall have been made, provided that if such Person is not a publicly traded entity whose common stock or equivalent equity
security is quoted or listed for trading on an Eligible Market, Successor Entity shall mean such Person’s Parent Entity.

(w)          “Trading Day” means any day on which the Common Stock is traded on the Principal Market, or, if the Principal Market is not the principal
trading market for the Common Stock, then on the principal securities exchange or securities market on which the Common Stock is then traded; provided that “Trading Day” shall
not include any day on which the Common Stock is scheduled to trade on such exchange or market for less than 4.5 hours or any day that the Common Stock is suspended from
trading during the final hour of trading on such exchange or market (or if such exchange or market does not designate in advance the closing time of trading on such exchange or
market, then during the hour ending at 4:00:00 p.m., New York Time).

(x)          “Voting Stock” of a Person means capital stock of such Person of the class or classes pursuant to which the holders thereof have the general
voting power to elect, or the general power to appoint, at least a majority of the board of directors, managers or trustees of such Person (irrespective of whether or not at the time
capital stock of any other class or classes shall have or might have voting power by reason of the happening of any contingency).

27.         DISCLOSURE. Upon receipt or delivery by the Company of any notice in accordance with the terms of this Note, unless the Company has in good faith
determined that the matters relating to such notice do not constitute material, nonpublic information relating to the Company or its Subsidiaries, the Company shall within four
Business  Days after any such receipt or delivery publicly disclose such material, nonpublic information on a  Current  Report on  Form 8-K or otherwise.  In the event that the
Company  believes  that  a  notice  contains  material,  nonpublic  information  relating  to  the  Company  or  its  Subsidiaries,  the  Company  so  shall  indicate  to  such  Holder
contemporaneously with delivery of such notice, and in the absence of any such indication, the Holder shall be allowed to presume that all matters relating to such notice do not
constitute material, nonpublic information relating to the Company or its Subsidiaries.

[Signature Page Follows]

Exhibit A-10

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, the Company has caused this Note to be duly executed as of the Issuance Date set out above.

APPLIED DNA SCIENCES, INC.

By:

Name:
Title:

[signature page to Form of Secured Convertible Note]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
EXHIBIT I

APPLIED DNA SCIENCES, INC.
CONVERSION NOTICE

Reference is made to the Secured Convertible Note (the “Note”) issued to the undersigned by Applied DNA Sciences, Inc. (the “Company”). In accordance with and pursuant to
the Note, the undersigned hereby elects to convert the Conversion Amount (as defined in the Note) of the Note indicated below into Conversion Shares (as defined in the Note) of
the Company, as of the date specified below.

Date of Conversion:  

Aggregate Conversion Amount to be converted:

Please confirm the following information:

Conversion Price:

Number of shares of Common Stock to be
issued:

Please issue the Common Stock into which the Conversion Amount of the Note is being converted in the following name and to the following address:

Issue to: 

Facsimile Number:

Authorization:

By:

Title:

Dated:

Account Number:
(if electronic book entry transfer)

Transaction Code Number:
(if electronic book entry transfer)

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
The Company hereby acknowledges this Conversion Notice and hereby directs American Stock Transfer & Trust Company to issue the above indicated number
of shares of Common Stock in accordance with the Transfer Agent Instructions dated [●], 2018 from the Company and acknowledged and agreed to by American Stock Transfer &
Trust Company.

ACKNOWLEDGMENT

APPLIED DNA SCIENCES, INC

By:

Name:
Title:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Exhibit B

Registration Rights Agreement

 
 
 
 
 
REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of August 31, 2018, by and among Applied DNA Sciences, Inc., a Delaware corporation,
with  headquarters  located  at  50  Health  Sciences  Drive,  Stony  Brook,  New  York  11790  (the  “Company”),  and  the  undersigned  buyers  (each,  a  “Buyer”,  and  collectively,  the
“Buyers”).

REGISTRATION RIGHTS AGREEMENT

WHEREAS:

A. In connection with the Securities Purchase Agreement, dated as of August 31, 2018, by and among the Company and the Buyers (the “ Securities Purchase
Agreement”), the Company has agreed, upon the terms and subject to the conditions set forth in the Securities Purchase Agreement, to issue and sell to each Buyer senior
secured convertible notes of the Company (the “Notes”), which may, among other things, be convertible into shares of the Company’s common stock, $0.001 par value per share
(the “Common Stock,” as converted, the “Conversion Shares”) in accordance with the terms of the Notes.

Securities Act of 1933, as amended, and the rules and regulations thereunder, or any similar successor statute (collectively, the “1933 Act”), and applicable state securities laws.

B. To induce the Buyers to execute and deliver the Securities Purchase Agreement, the Company has agreed to provide certain registration rights under the

NOW, THEREFORE, in consideration of the premises and the mutual covenants contained herein and other good and valuable consideration, the receipt and

sufficiency of which are hereby acknowledged, the Company and each of the Buyers hereby agree as follows:

1.           Definitions.

this Agreement, the following terms shall have the following meanings:

Capitalized terms used herein and not otherwise defined herein shall have the respective meanings set forth in the Securities Purchase Agreement. As used in

authorized or required by law to remain closed.

a.           “Business Day” means any day other than  Saturday,  Sunday or any other day on which commercial banks in the  City of  New  York are

b.           “Effective Date” means the date the Registration Statement (as defined below) is declared effective by the SEC.

Registrable Securities pursuant to Section 2, 45 days after the Filing Date, or if there is a review of the Registration Statement by the SEC, 90 days after the Filing Date.

c.           “Effectiveness Deadline” means, with respect to any registration statement required to be filed to cover the resale by the Investors of the

Securities pursuant to Section 2, the date on which such registration statement is filed with the SEC.

d.           “Filing Date” means, with respect to any registration statement required to be filed to cover the resale by the Investors of the Registrable

Exhibit B-1

 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
e.           “Filing Deadline” means with respect to any registration statement required to be filed to cover the resale by the Investors of the Registrable
Securities pursuant to Section 2, 60 days following the Demand Registration Request (as defined below), unless the Demand Registration Request is made after the end of the fiscal
year but before the financial statements for such fiscal year are available, in which case the Filing Deadline means the later of (i) 10 Business Days following the availability of the
financial statements for the year ended September 30, 2018 and (ii) 60 days following the Demand Registration Request.

f.            “Investor” means a Buyer or any transferee or assignee thereof to whom a Buyer assigns its rights under this Agreement and who agrees to
become bound by the provisions of this Agreement in accordance with Section 9 and any transferee or assignee thereof to whom a transferee or assignee assigns its rights under
this Agreement and who agrees to become bound by the provisions of this Agreement in accordance with Section 9.

and a government or any department or agency thereof.

g.           “Person” means an individual, a limited liability company, a partnership, a joint venture, a corporation, a trust, an unincorporated organization

defined below) in compliance with the 1933 Act and pursuant to Rule 415 and the declaration or ordering of effectiveness of such Registration Statement(s) by the SEC.

h.           “register,” “registered,” and “registration” refer to a registration effected by preparing and filing one or more Registration Statements (as

i.            “Registrable Securities” means (i) the Conversion Shares issued or issuable upon conversion or redemption of the Note and (ii) any share
capital of the Company issued or issuable with respect to the Conversion Shares or the Notes as a result of any stock split, stock dividend, recapitalization, exchange or similar
event or otherwise.

Registrable Securities.

j.            “Registration Statement” means a registration statement or registration statements of the Company filed under the 1933 Act covering the

k.          “Required Holders” means the holders of at least a majority of the Registrable Securities.

l.            “Rule 415” means Rule 415 under the 1933 Act or any successor rule providing for offering securities on a continuous or delayed basis.

m.           “SEC” means the United States Securities and Exchange Commission.

Exhibit B-2

 
  
 
 
 
 
 
 
 
 
 
 
 
2.          Registration.

a

.           Demand Registration.  Subject to the terms and conditions of this Agreement, if, at any time following the receipt by the  Company of a
Conversion Notice, as defined in the Securities Purchase Agreement, or a mandatory conversion pursuant to Section 8 of the Form of Note, the Company receives a written request
from the Required Holders that the Company register under the 1933 Act any of the Registrable Securities held by the Required Holders (such a written request being hereinafter
referred to as a “Demand Registration Request”), the Company shall file, as promptly as reasonably practicable but no later than the Filing Deadline, a registration statement under
the 1933 Act covering all of the Registrable Securities. The Registration Statement shall be on Form S-1 or any similar long-form registration statement. The Registration Statement
shall contain the “Selling Shareholders” and “Plan of Distribution” sections in substantially the form attached hereto as Exhibit B. The Company shall use its reasonable efforts to
cause the registration statement to be declared effective or otherwise to become effective under the 1933 Act as soon as reasonably practicable but, in any event, no later than the
Effectiveness  Deadline.  By  9:30  am  on  the  date  following  the  Effective  Date,  the  Company  shall  file  with  the  SEC  in  accordance  with  Rule  424  under  the  1933 Act  the  final
prospectus to be used in connection with sales pursuant to such Registration Statement.

b .           Eligibility for Form S-3. If the Company is eligible to use Form S-3, or any similar short-form registration statement, to register the Registrable

Securities, then the Company may use Form S-3 in lieu of Form S-1.

3.          Related Obligations.

At such time as the Company is obligated to file a Registration Statement with the SEC pursuant to Section 2, the Company will use its reasonable efforts to
effect the registration of the Registrable Securities in accordance with the intended method of disposition thereof and, pursuant thereto, the Company shall have the following
obligations:

a.           The Company shall promptly prepare and file with the SEC a Registration Statement with respect to the Registrable Securities and use its
reasonable efforts to cause such Registration Statement relating to the Registrable Securities to become effective as soon as reasonably practicable after such filing (but in no
event later than the Effectiveness Deadline). The Company shall keep each Registration Statement effective pursuant to Rule 415 at all times until the earlier of (i) the date as of
which  the  Investors  may  sell  all  of  the  Registrable  Securities  covered  by  such  Registration  Statement  without  restriction  or  limitation  pursuant  to  Rule  144  and  without  the
requirement to be in compliance with Rule 144(c)(1) (or any successor thereto) promulgated under the 1933 Act or (ii) the date on which the Investors shall have sold all of the
Registrable  Securities  covered  by  such  Registration  Statement  (the  “Registration  Period”).  The  Company  shall  ensure  that  each  Registration  Statement  (including  any
amendments or supplements thereto and prospectuses contained therein) shall not contain any untrue statement of a material fact or omit to state a material fact required to be
stated therein, or necessary to make the statements therein (in the case of prospectuses, in the light of the circumstances in which they were made) not misleading. The term
“reasonable efforts” shall mean, among other things, that the Company shall submit to the SEC, within five (5) Business Days after the later of the date that (i) the Company learns
that no review of a particular Registration Statement will be made by the staff of the SEC or that the staff has no further comments on a particular Registration Statement, as the
case may be, and (ii) the approval of Investors whose Registrable Securities are included in such Registration Statement (which approval is immediately sought), a request for
acceleration of effectiveness of such Registration Statement to a time and date, subject to acceptance by the SEC, not later than five (5) Business Days after the submission of
such request.

Exhibit B-3

 
  
 
 
 
 
 
 
 
 
b.           The Company shall prepare and file with the SEC such amendments (including post-effective amendments) and supplements to a Registration
Statement and the prospectus used in connection with such Registration Statement, which prospectus is to be filed pursuant to Rule 424 promulgated under the 1933 Act, as may
be necessary to keep such Registration Statement effective at all times during the Registration Period, and, during such period, comply with the provisions of the 1933 Act with
respect to the disposition of all Registrable Securities of the Company covered by such Registration Statement until such time as all of such Registrable Securities shall have been
disposed of in accordance with the intended methods of disposition by the seller or sellers thereof as set forth in such Registration Statement. In the case of amendments and
supplements to a Registration Statement which are required to be filed pursuant to this Agreement (including pursuant to this Section 3(b)) by reason of the Company filing a
report on Form 10-Q, Form 10-K, or any analogous report under the Securities Exchange Act of 1934, as amended (the “1934 Act”), the Company shall have incorporated such
report by reference into such Registration Statement, if applicable, or shall file such amendments or supplements with the SEC as soon as reasonably practicable after the 1934 Act
report is filed which created the requirement for the Company to amend or supplement such Registration Statement.

c.           The Company shall use its reasonable efforts to (i) register and qualify, unless an exemption from registration and qualification applies, the
resale by the Investors of the Registrable Securities covered by a Registration Statement under such other securities or “blue sky” laws of all applicable jurisdictions in the United
States, (ii) prepare and file in those jurisdictions, such amendments (including post-effective amendments) and supplements to such registrations and qualifications as may be
necessary to maintain the effectiveness thereof during the Registration Period, (iii) take such other actions as may be necessary to maintain such registrations and qualifications in
effect at all times during the Registration Period, and (iv) take all other actions reasonably necessary or advisable to qualify the Registrable Securities for sale in such jurisdictions;
provided, however, that the Company shall not be required in connection therewith or as a condition thereto to (w) make any change to its certificate of incorporation or bylaws, (x)
qualify to do business in any jurisdiction where it would not otherwise be required to qualify but for this Section 3(d), (y) subject itself to general taxation in any such jurisdiction,
or (z) file a general consent to service of process in any such jurisdiction. The Company shall promptly notify each Investor of the Registrable Securities covered by a Registration
Statement of the receipt by the Company of any notification with respect to the suspension of the registration or qualification of any of the Registrable Securities for sale under the
securities or “blue sky” laws of any jurisdiction in the United States or its receipt of notice of the initiation or threatening of any proceeding for such purpose.

Exhibit B-4

 
  
 
 
 
 
d.           The Company shall notify each Investor of the Registrable Securities covered by a Registration Statement in writing of the happening of any
event, as promptly as reasonably practicable after becoming aware of such event, as a result of which the prospectus included in a Registration Statement, as then in effect,
includes an untrue statement of a material fact or omission to state a material fact required to be stated therein or necessary to make the statements therein, in the light of the
circumstances under which they were made, not misleading (provided that in no event shall such notice contain any material, nonpublic information), and promptly prepare a
supplement or amendment to such Registration Statement to correct such untrue statement or omission, and deliver such number of copies of such supplement or amendment to
such Investor as such Investor may reasonably request. The Company shall also promptly notify each Investor of the Registrable Securities covered by a Registration Statement in
writing (i) when a prospectus or any prospectus supplement or post-effective amendment has been filed, and when a Registration Statement or any post-effective amendment has
become effective (notification of such effectiveness shall be delivered to each such Investor by facsimile or e-mail on the same day of such effectiveness), (ii) of any request by the
SEC for amendments or supplements to a Registration Statement or related prospectus or related information, and (iii) of the Company’s reasonable determination that a post-
effective amendment to a Registration Statement would be appropriate.

e.           The Company shall use its reasonable efforts to prevent the issuance of any stop order or other suspension of effectiveness of a Registration
Statement, or the suspension of the qualification of any of the  Registrable  Securities for sale in any jurisdiction and, if such an order or suspension is issued, to obtain the
withdrawal of such order or suspension at the earliest possible moment and to notify each Investor who holds Registrable Securities being sold of the issuance of such order and
the resolution thereof or its receipt of notice of the initiation or threat of any proceeding for such purpose.

f.            If any Investors of the Registrable Securities covered by a Registration Statement is required under applicable securities laws to be described in
the Registration Statement as an underwriter, at the reasonable request of such Investor, the Company shall furnish to such Investor, on the date of the effectiveness of the
Registration Statement and thereafter from time to time on such dates as an Investor may reasonably request (i) a letter, dated as of such date, from the Company’s independent
certified  public  accountants  in  form  and  substance  as  is  customarily  given  by  independent  certified  public  accountants  to  underwriters  in  an  underwritten  public  offering,
addressed to such Investor, and (ii) an opinion, dated as of such date, of counsel representing the Company for purposes of such Registration Statement, in form, scope and
substance as is customarily given in an underwritten public offering, addressed to such Investor.

g.           The Company shall hold in confidence and not make any disclosure of information concerning an Investor provided to the Company unless (i)
disclosure of such information is necessary to comply with federal or state securities laws, (ii) the disclosure of such information is necessary to avoid or correct a misstatement or
omission in any Registration Statement, (iii) the release of such information is ordered pursuant to a subpoena or other final, non-appealable order from a court or governmental
body of competent jurisdiction, or (iv) such information has been made generally available to the public other than by disclosure in violation of this Agreement or any other
agreement. The Company agrees that it shall, upon learning that disclosure of such information concerning an Investor of the Registrable Securities covered by a Registration
Statement is sought in or by a court or governmental body of competent jurisdiction or through other means, give prompt written notice to such Investor and allow such Investor,
at such Investor’s expense, to undertake appropriate action to prevent disclosure of, or to obtain a protective order for, such information.

Exhibit B-5

 
  
 
 
 
 
 
 
or quoted on each securities exchange, bulletin board or quotation system on which securities of the same class or series issued by the Company are then listed or quoted.

h.           The Company shall use its reasonable efforts either to (i) cause all of the Registrable Securities covered by a Registration Statement to be listed

i.            The Company shall cooperate with the Investors who hold Registrable Securities being offered and, to the extent applicable, facilitate the timely
preparation and delivery of certificates (not bearing any restrictive legend) representing the Registrable Securities to be offered pursuant to a Registration Statement and enable
such certificates to be in such denominations or amounts, as the case may be, as the Investors may reasonably request and registered in such names as the Investors may request.

j.            If requested by an Investor of the Registrable Securities covered by a Registration Statement, the Company shall (i) as soon as reasonably
practicable incorporate in a prospectus supplement or post-effective amendment such information as such Investor reasonably requests to be included therein relating to the sale
and distribution of Registrable Securities, including, without limitation, information with respect to the number of Registrable Securities being offered or sold, the purchase price
being paid therefor and any other terms of the offering of the Registrable Securities to be sold in such offering; (ii) as soon as reasonably practicable make all required filings of
such prospectus supplement or post-effective amendment after being notified of the matters to be incorporated in such prospectus supplement or post-effective amendment; and
(iii) as soon as reasonably practicable, supplement or make amendments to any Registration Statement if reasonably requested by such Investor holding any Registrable Securities.

approved by such other governmental agencies or authorities as may be necessary to consummate the disposition of such Registrable Securities.

k.          The Company shall use its reasonable efforts to cause the Registrable Securities covered by a Registration Statement to be registered with or

registration hereunder.

l.            The Company shall otherwise use its reasonable efforts to comply with all applicable rules and regulations of the SEC in connection with any

m.           Within two (2) Business Days after a Registration Statement which covers Registrable Securities is ordered effective by the SEC, the Company
shall deliver, and shall cause legal counsel for the  Company to deliver, to the transfer agent for such  Registrable  Securities (with copies to the  Investors whose  Registrable
Securities are included in such Registration Statement) confirmation that such Registration Statement has been declared effective by the SEC in the form attached hereto as Exhibit
A.

Exhibit B-6

 
  
 
 
 
 
 
 
 
 
n.           Notwithstanding anything to the contrary herein, at any time after the Effective Date, the Company may delay the disclosure of material, non-
public information concerning the Company the disclosure of which at the time is not, in the good faith opinion of the Board of Directors of the Company and its counsel, in the
best  interest  of  the  Company  and,  in  the  opinion  of  counsel  to  the  Company  otherwise  required  (a  “Grace  Period”); provided that  no  Grace  Period  shall  exceed  ten  (10)
consecutive days and during any three hundred sixty five (365) day period such Grace Periods shall not exceed an aggregate of forty (40) days and the first day of any Grace Period
must be at least five (5) trading days after the last day of any prior Grace Period (each, an “Allowable Grace Period”). For purposes of determining the length of a Grace Period
above, the Grace Period shall begin on and include the date the Investors receive the notice referred to in clause (i) and shall end on and include the later of the date the Investors
receive the notice referred to in clause (ii) and the date referred to in such notice. The provisions of Section 3(f) hereof shall not be applicable during the period of any Allowable
Grace Period. Upon expiration of the Grace Period, the Company shall again be bound by the first sentence of Section 3(e) with respect to the information giving rise thereto unless
such material, non-public information is no longer applicable. Notwithstanding anything to the contrary, the Company shall cause its transfer agent to deliver unlegended shares of
Common Stock to a transferee of an Investor in accordance with the terms of the Securities Purchase Agreement in connection with any sale of Registrable Securities with respect
to which an Investor has entered into a contract for sale and delivered a copy of the prospectus included as part of the Registration Statement (unless an exemption from such
prospectus delivery requirement exists) prior to the Investor’s receipt of the notice of a Grace Period and for which the Investor has not yet settled.

4.          Obligations of the Investors.

a.           At least five (5) Business Days prior to the first anticipated filing date of a Registration Statement, the Company shall notify each Investor
whose Registrable Securities are to be included in a Registration Statement in writing of the information the Company requires from each such Investor. It shall be a condition
precedent to the obligations of the Company to complete the registration pursuant to this Agreement with respect to the Registrable Securities of a particular Investor that such
Investor shall furnish to the Company such information regarding itself, the Registrable Securities held by it and the intended method of disposition of the Registrable Securities
held by it as shall be reasonably required to effect the effectiveness of the registration of such Registrable Securities and shall execute such documents in connection with such
registration as the Company may reasonably request.

requested by the Company in connection with the preparation and filing of any Registration Statement hereunder.

b.           Each Investor whose Registrable Securities are to be included in a Registration Statement agrees to cooperate with the Company as reasonably

c.           Each Investor whose Registrable Securities are to be included in a Registration Statement agrees that, upon receipt of any notice from the
Company of the happening of any event of the kind described in Section 3(f) or the first sentence of 3(e), such Investor will immediately discontinue disposition of Registrable
Securities pursuant to any Registration Statement(s) covering such Registrable Securities until such Investor’s receipt of the copies of the supplemented or amended prospectus
contemplated by Section 3(f) or the first sentence of 3(e) or receipt of notice that no supplement or amendment is required.

d.           Each Investor whose Registrable Securities are to be included in a Registration Statement covenants and agrees that it will comply with the
prospectus delivery requirements of the 1933 Act as applicable to it or an exemption therefrom in connection with sales of Registrable Securities pursuant to the Registration
Statement.

Exhibit B-7

 
  
 
 
 
 
 
 
 
 
5.          Expenses of Registration.

All reasonable expenses, other than underwriting discounts and commissions, incurred in connection with registrations, filings or qualifications pursuant to
Sections 2 and 3, including, without limitation, all registration, listing and qualifications fees, printers and accounting fees, and fees and disbursements of counsel for the Company
shall be paid by the Company.

6.          Indemnification.

In the event any Registrable Securities are included in a Registration Statement under this Agreement:

a.                      To  the  fullest  extent  permitted  by  law,  the  Company  will,  and  hereby  does,  indemnify,  hold  harmless  and  defend  each  Investor  whose
Registrable Securities are included in a Registration Statement, the directors, officers, members, partners, employees, agents, representatives of, and each Person, if any, who
controls any Investor whose Registrable Securities are included in a Registration Statement within the meaning of the 1933 Act or the 1934 Act (each, an “ Indemnified Person”),
against any losses, claims, damages, liabilities, judgments, fines, penalties, charges, costs, reasonable attorneys’ fees, amounts paid in settlement or expenses, joint or several,
(collectively, “Claims”) incurred in investigating, preparing or defending any action, claim, suit, inquiry, proceeding, investigation or appeal taken from the foregoing by or before
any court or governmental, administrative or other regulatory agency, body or the SEC, whether pending or threatened, whether or not an indemnified party is or may be a party
thereto (“Indemnified Damages”), to which any of them may become subject insofar as such Claims (or actions or proceedings, whether commenced or threatened, in respect
thereof) arise out of or are based upon: (i) any untrue statement or alleged untrue statement of a material fact in a Registration Statement or any post-effective amendment thereto
or in any filing made in connection with the qualification of the offering under the securities or other “blue sky” laws of any jurisdiction in which Registrable Securities are offered
(“Blue Sky Filing”), or the omission or alleged omission to state a material fact required to be stated therein or necessary to make the statements therein not misleading, (ii) any
untrue statement or alleged untrue statement of a material fact contained in any preliminary prospectus if used prior to the effective date of such  Registration  Statement, or
contained in the final prospectus (as amended or supplemented, if the Company files any amendment thereof or supplement thereto with the SEC) or the omission or alleged
omission to state therein any material fact necessary to make the statements made therein, in the light of the circumstances under which the statements therein were made, not
misleading, (iii) any violation or alleged violation by the Company of the 1933 Act, the 1934 Act, any other law, including, without limitation, any state securities law, or any rule or
regulation thereunder relating to the offer or sale of the Registrable Securities pursuant to a Registration Statement or (iv) any violation of this Agreement (the matters in the
foregoing clauses (i) through (iv) being, collectively, “Violations”). Subject to Section 6(c), the Company shall reimburse the Indemnified Persons, promptly as such expenses are
incurred and are due and payable, for any legal fees or other reasonable expenses incurred by them in connection with investigating or defending any such Claim. Notwithstanding
anything to the contrary contained herein, the indemnification agreement contained in this Section 6(a): (i) shall not apply to a Claim by an Indemnified Person arising out of or
based upon a Violation which occurs in reliance upon and in conformity with information furnished in writing to the Company by such Indemnified Person for such Indemnified
Person expressly for use in connection with the preparation of the Registration Statement or any such amendment thereof or supplement thereto, if such prospectus was timely
made available by the Company pursuant to Section 3(c) and (ii) shall not apply to amounts paid in settlement of any Claim if such settlement is effected without the prior written
consent of the Company, which consent shall not be unreasonably withheld or delayed. Such indemnity shall remain in full force and effect regardless of any investigation made
by or on behalf of the Indemnified Person and shall survive the transfer of the Registrable Securities by the Investors pursuant to Section 9.

Exhibit B-8

 
  
 
 
 
 
 
 
 
b.           In connection with any Registration Statement in which an Investor is participating, each such Investor agrees to severally and not jointly
indemnify, hold harmless and defend, to the same extent and in the same manner as is set forth in Section 6(a), the Company, each of its directors, each of its officers who signs the
Registration Statement and each Person, if any, who controls the Company within the meaning of the 1933 Act or the 1934 Act (each, an “ Indemnified Party”), against any Claim or
Indemnified Damages to which any of them may become subject, under the 1933 Act, the 1934 Act or otherwise, insofar as such Claim or Indemnified Damages arise out of or are
based upon any “Violation”, in each case to the extent, and only to the extent, that such Violation occurs in reliance upon and in conformity with written information furnished to
the Company by such Investor expressly for use in connection with such Registration Statement; and, subject to Section 6(c), such Investor will reimburse any legal or other
expenses reasonably incurred by an Indemnified Party in connection with investigating or defending any such Claim; provided, however, that the indemnity agreement contained
in this Section 6(b) and the agreement with respect to contribution contained in Section 7 shall not apply to amounts paid in settlement of any Claim if such settlement is effected
without the prior written consent of such Investor, which consent shall not be unreasonably withheld or delayed; provided, further, however, that the Investor shall be liable under
this Section 6(b) for only that amount of a Claim or Indemnified Damages as does not exceed the net proceeds to such Investor as a result of the sale of Registrable Securities
pursuant to such Registration Statement. Such indemnity shall remain in full force and effect regardless of any investigation made by or on behalf of such Indemnified Party and
shall survive the transfer of the Registrable Securities by the Investors pursuant to Section 9. Notwithstanding anything to the contrary contained herein, the indemnification
agreement contained in this Section 6(b) with respect to any preliminary prospectus shall not inure to the benefit of any Indemnified Party if the untrue statement or omission of
material fact contained in the preliminary prospectus was corrected on a timely basis in the prospectus, as then amended or supplemented.

Exhibit B-9

 
  
 
 
 
c.           Promptly after receipt by an Indemnified Person or Indemnified Party under this Section 6 of notice of the commencement of any action or
proceeding (including any governmental action or proceeding) involving a Claim, such Indemnified Person or Indemnified Party shall, if a Claim in respect thereof is to be made
against any indemnifying party under this Section 6, deliver to the indemnifying party a written notice of the commencement thereof, and the indemnifying party shall have the
right to participate in, and, to the extent the indemnifying party so desires, jointly with any other indemnifying party similarly noticed, to assume control of the defense thereof with
counsel mutually satisfactory to the indemnifying party and the Indemnified Person or the Indemnified Party, as the case may be; provided, however, that an Indemnified Person or
Indemnified Party shall have the right to retain its own counsel with the fees and expenses of not more than one counsel for such Indemnified Person or Indemnified Party to be
paid by the indemnifying party, if, in the reasonable opinion of counsel retained by the indemnifying party, the representation by such counsel of the Indemnified Person or
Indemnified Party and the indemnifying party would be inappropriate due to actual or potential differing interests between such Indemnified Person or Indemnified Party and any
other party represented by such counsel in such proceeding. In the case of an Indemnified Person, legal counsel referred to in the immediately preceding sentence shall be selected
by the Investors holding at least a majority in interest of the Registrable Securities included in the Registration Statement to which the Claim relates. The Indemnified Party or
Indemnified Person shall cooperate fully with the indemnifying party in connection with any negotiation or defense of any such action or Claim by the indemnifying party and shall
furnish to the indemnifying party all information reasonably available to the Indemnified Party or Indemnified Person which relates to such action or Claim. The indemnifying party
shall keep the Indemnified Party or Indemnified Person reasonably apprised at all times as to the status of the defense or any settlement negotiations with respect thereto. No
indemnifying party shall be liable for any settlement of any action, claim or proceeding effected without its prior written consent, provided, however, that the indemnifying party
shall not unreasonably withhold, delay or condition its consent. No indemnifying party shall, without the prior written consent of the Indemnified Party or Indemnified Person,
consent to entry of any judgment or enter into any settlement or other compromise which does not include as an unconditional term thereof the giving by the claimant or plaintiff
to such Indemnified Party or Indemnified Person of a release from all liability in respect to such Claim or litigation, and such settlement shall not include any admission as to fault
on the part of the Indemnified Party. Following indemnification as provided for hereunder, the indemnifying party shall be subrogated to all rights of the Indemnified Party or
Indemnified Person with respect to all third parties, firms or corporations relating to the matter for which indemnification has been made. The failure to deliver written notice to the
indemnifying party within a reasonable time of the commencement of any such action shall not relieve such indemnifying party of any liability to the  Indemnified  Person or
Indemnified Party under this Section 6, except to the extent that the indemnifying party is prejudiced in its ability to defend such action.

or defense, as and when bills are received or Indemnified Damages are incurred.

d.           The indemnification required by this Section 6 shall be made by periodic payments of the amount thereof during the course of the investigation

Person against the indemnifying party or others, and (ii) any liabilities the indemnifying party may be subject to pursuant to the law.

e.           The indemnity agreements contained herein shall be in addition to (i) any cause of action or similar right of the Indemnified Party or Indemnified

7.          Contribution.

To the extent any indemnification by an indemnifying party is prohibited or limited by law, the indemnifying party agrees to make the maximum contribution with
respect to any amounts for which it would otherwise be liable under Section 6 to the fullest extent permitted by law; provided, however, that: (i) no Person involved in the sale of
Registrable Securities which Person is guilty of fraudulent misrepresentation (within the meaning of Section 11(f) of the 1933 Act) in connection with such sale shall be entitled to
contribution from any Person involved in such sale of Registrable Securities who was not guilty of fraudulent misrepresentation; and (ii) contribution by any seller of Registrable
Securities shall be limited in amount to the net amount of proceeds received by such seller from the sale of such Registrable Securities pursuant to such Registration Statement.

Exhibit B-10

 
  
 
 
 
 
 
 
 
8.          Reports Under the 1934 Act.

may at any time permit the Investors to sell securities of the Company to the public without registration (“Rule 144”), the Company agrees to:

With a view to making available to the Investors the benefits of Rule 144 promulgated under the 1933 Act or any other similar rule or regulation of the SEC that

a.           make and keep public information available, as those terms are understood and defined in Rule 144;

the Company remains subject to such requirements and the filing of such reports and other documents is required for the applicable provisions of Rule 144; and

b.           file with the SEC in a timely manner all reports and other documents required of the Company under the 1933 Act and the 1934 Act so long as

c.           furnish to each Investor so long as such Investor owns Registrable Securities, promptly upon request, (i) a written statement by the Company, if
true, that it has complied with the reporting requirements of Rule 144, the 1933 Act and the 1934 Act, (ii) a copy of the most recent annual or quarterly report of the Company and
such other reports and documents so filed by the Company, and (iii) such other information as may be reasonably requested to permit the Investors to sell such securities pursuant
to Rule 144 without registration.

9.          Assignment of Registration Rights.

The  rights  under  this Agreement  shall  be  automatically  assignable  by  the  Investors  to  any  transferee  of  all  or  any  portion  of  such  Investor’s  Registrable
Securities if: (i) the Investor agrees in writing with the transferee or assignee to assign such rights, and a copy of such agreement is furnished to the Company within a reasonable
time after such assignment; (ii) the Company is, within a reasonable time after such transfer or assignment, furnished with written notice of (a) the name and address of such
transferee or assignee, and (b) the securities with respect to which such registration rights are being transferred or assigned; (iii) immediately following such transfer or assignment
the further disposition of such securities by the transferee or assignee is restricted under the 1933 Act or applicable state securities laws; (iv) at or before the time the Company
receives  the  written  notice  contemplated  by  clause  (ii)  of  this  sentence  the  transferee  or  assignee  agrees  in  writing  with  the  Company  to  be  bound  by  all  of  the  provisions
contained herein; and (v) such transfer shall have been made in accordance with the applicable requirements of the Securities Purchase Agreement.

10.        Amendment of Registration Rights.

Provisions of this Agreement may be amended and the observance thereof may be waived (either generally or in a particular instance and either retroactively or
prospectively), only with the written consent of the Company and the Required Holders. Any amendment or waiver effected in accordance with this Section 10 shall be binding
upon  each  Investor  and  the  Company.  No  such  amendment  shall  be  effective  to  the  extent  that  it  applies  to  less  than  all  of  the  holders  of  the  Registrable  Securities.  No
consideration shall be offered or paid to any Person to amend or consent to a waiver or modification of any provision of any of this Agreement unless the same consideration also
is offered to all of the parties to this Agreement.

Exhibit B-11

 
  
 
 
 
 
 
 
 
 
 
 
 
11.        Miscellaneous.

a.           A Person is deemed to be a holder of Registrable Securities whenever such Person owns or is deemed to own of record such Registrable
Securities. If the Company receives conflicting instructions, notices or elections from two or more Persons with respect to the same Registrable Securities, the Company shall act
upon the basis of instructions, notice or election received from the such record owner of such Registrable Securities.

b.           Any notices, consents, waivers or other communications required or permitted to be given under the terms of this Agreement must be in writing
and  will  be  deemed  to  have  been  delivered:  (i)  upon  receipt,  when  delivered  personally;  (ii)  upon  receipt,  when  sent  by  facsimile  (provided  confirmation  of  transmission  is
mechanically or electronically generated and kept on file by the sending party); or (iii) one (1) Business Day after deposit with a nationally recognized overnight delivery service, in
each case properly addressed to the party to receive the same. The addresses and facsimile numbers for such communications shall be:

If to the Company:

Applied DNA Sciences, Inc.
50 Health Sciences Drive, Suite 113
Stony Brook, New York 11790
Telephone: (631) 240-8800
Attention: Chief Financial Officer

With copies to:

Pepper Hamilton LLP
620 Eighth Avenue, 37th Floor
New York, NY 10018
Telephone: (212) 808-2711
Facsimile: (212) 658-9982
Attention: Merrill Kraines, Esq.

If to a Buyer, to its address and facsimile number set forth on the Schedule of Buyers attached hereto, with copies to such Buyer’s representatives as set forth on the Schedule of
Buyers, or to such other address and/or facsimile number and/or to the attention of such other Person as the recipient party has specified by written notice given to each other
party five (5) days prior to the effectiveness of such change. Written confirmation of receipt (A) given by the recipient of such notice, consent, waiver or other communication, (B)
mechanically or electronically generated by the sender’s facsimile machine containing the time, date, recipient facsimile number and an image of the first page of such transmission
or (C) provided by a courier or overnight courier service shall be rebuttable evidence of personal service, receipt by facsimile or receipt from a nationally recognized overnight
delivery service in accordance with clause (i), (ii) or (iii) above, respectively.

Exhibit B-12

 
  
 
 
 
 
 
 
 
 
 
 
shall not operate as a waiver thereof.

c.           Failure of any party to exercise any right or remedy under this Agreement or otherwise, or delay by a party in exercising such right or remedy,

d.           All questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be governed by the internal laws of
the State of New York, without giving effect to any choice of law or conflict of law provision or rule (whether of the State of New York or any other jurisdictions) that would cause
the application of the laws of any jurisdictions other than the State of New York. Each party hereby irrevocably submits to the exclusive jurisdiction of the state and federal courts
sitting in The City of New York, Borough of Manhattan, for the adjudication of any dispute hereunder or in connection herewith or with any transaction contemplated hereby or
discussed herein, and hereby irrevocably waives, and agrees not to assert in any suit, action or proceeding, any claim that it is not personally subject to the jurisdiction of any
such court, that such suit, action or proceeding is brought in an inconvenient forum or that the venue of such suit, action or proceeding is improper. Each party hereby irrevocably
waives personal service of process and consents to process being served in any such suit, action or proceeding by mailing a copy thereof to such party at the address for such
notices to it under this Agreement and agrees that such service shall constitute good and sufficient service of process and notice thereof. Nothing contained herein shall be
deemed to limit in any way any right to serve process in any manner permitted by law. If any provision of this Agreement shall be invalid or unenforceable in any jurisdiction, such
invalidity or unenforceability shall not affect the validity or enforceability of the remainder of this Agreement in that jurisdiction or the validity or enforceability of any provision of
this Agreement in any other jurisdiction. EACH PARTY HEREBY IRREVOCABLY WAIVES ANY RIGHT IT MAY HAVE, AND AGREES NOT TO REQUEST, A JURY TRIAL
FOR  THE ADJUDICATION  OF ANY  DISPUTE  HEREUNDER  OR  IN  CONNECTION  HEREWITH  OR ARISING  OUT  OF  THIS AGREEMENT  OR ANY  TRANSACTION
CONTEMPLATED HEREBY.

e.           This Agreement, the other Transaction Documents (as defined in the Securities Purchase Agreement) and the instruments referenced herein and
therein  constitute  the  entire  agreement  among  the  parties  hereto  with  respect  to  the  subject  matter  hereof  and  thereof.  There  are  no  restrictions,  promises,  warranties  or
undertakings, other than those set forth or referred to herein and therein. This Agreement, the other Transaction Documents and the instruments referenced herein and therein
supersede all prior agreements and understandings among the parties hereto with respect to the subject matter hereof and thereof.

of each of the parties hereto.

f.            Subject to the requirements of Section 9, this Agreement shall inure to the benefit of and be binding upon the permitted successors and assigns

g.           The headings in this Agreement are for convenience of reference only and shall not limit or otherwise affect the meaning hereof.

h.           This Agreement may be executed in identical counterparts, each of which shall be deemed an original but all of which shall constitute one and
the same agreement. This Agreement, once executed by a party, may be delivered to the other party hereto by facsimile transmission of a copy of this Agreement bearing the
signature of the party so delivering this Agreement.

Exhibit B-13

 
  
 
 
 
 
 
 
 
 
i.            Each party shall do and perform, or cause to be done and performed, all such further acts and things, and shall execute and deliver all such other
agreements, certificates, instruments and documents, as any other party may reasonably request in order to carry out the intent and accomplish the purposes of this Agreement
and the consummation of the transactions contemplated hereby.

specified in this Agreement, by the Required Holders.

j.            All consents and other determinations required to be made by the Investors pursuant to this Agreement shall be made, unless otherwise

strict construction will be applied against any party.

k.          The language used in this Agreement will be deemed to be the language chosen by the parties to express their mutual intent and no rules of

of, nor may any provision hereof be enforced by, any other Person.

l.            This Agreement is intended for the benefit of the parties hereto and their respective permitted successors and assigns, and is not for the benefit

m.           The obligations of each Investor hereunder are several and not joint with the obligations of any other Investor, and no provision of this
Agreement is intended to confer any obligations on any Investor vis-à-vis any other Investor. Nothing contained herein, and no action taken by any Investor pursuant hereto,
shall be deemed to constitute the Investors as a partnership, an association, a joint venture or any other kind of entity, or create a presumption that the Investors are in any way
acting in concert or as a group with respect to such obligations or the transactions contemplated herein.

[Signature Page Follows]

Exhibit B-14

 
  
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Registration Rights Agreement to be duly executed

as of the date first written above.

COMPANY:

APPLIED DNA SCIENCES, INC.

By:

Name: Beth Jantzen
Title: Chief Financial Officer

Exhibit B-15

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IN WITNESS WHEREOF, each Buyer and the Company have caused their respective signature page to this Registration Rights Agreement to be duly executed

as of the date first written above.

[BUYERS]:

By:

Name:
Title:

Exhibit B-16

 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Buyer

SCHEDULE OF BUYERS

Buyer’s Address and 
Facsimile Number

Exhibit B-17

Buyer’s Representative’s 
Address
and Facsimile Number

 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
FORM OF NOTICE OF EFFECTIVENESS
OF REGISTRATION STATEMENT

American Stock Transfer and Trust Company
Operations Center
6201 15th Ave., Third Floor
Brooklyn, New York 11219
Telephone: (718) 921-8210
Attention: [●]

Re: APPLIED DNA SCIENCES, INC.

Ladies and Gentlemen:

We are counsel to Applied DNA Sciences, Inc., a Delaware corporation (the “ Company”), and have represented the Company in connection with that certain Securities Purchase
Agreement, dated as of [●], 2018 (the “Securities Purchase Agreement”), entered into by and among the Company and the buyers named therein (collectively, the “Holders”)
pursuant to which the Company issued to the Holders secured convertible notes (the “Notes”) which are convertible into the Company’s common stock, $0.001 par value per share
(the “Common Stock”). Pursuant to the Securities Purchase Agreement, the Company also has entered into a Registration Rights Agreement with the Holders (the “ Registration
Rights Agreement”)  pursuant  to  which  the  Company  agreed,  among  other  things,  to  register  the  resale  of  the  Registrable  Securities  (as  defined  in  the  Registration  Rights
Agreement), including the shares of Common Stock issuable upon conversion of the Notes under the Securities Act of 1933, as amended (the “1933 Act”). In connection with the
Company’s obligations under the Registration Rights Agreement, on _______, 201_, the Company filed a Registration Statement on Form S-1 (File No. 333-_____________) (the
“Registration  Statement”)  with  the  Securities  and  Exchange  Commission  (the  “SEC”)  relating  to  the  Registrable  Securities  which  names  each  of  the  Holders  as  a  selling
shareholder thereunder.

In  connection  with  the  foregoing,  we  advise  you  that  the  SEC  has  entered  an  order  declaring  the  Registration  Statement  effective  under  the  1933 Act  at  [ENTER  TIME  OF
EFFECTIVENESS] on [ENTER DATE OF EFFECTIVENESS] and we have no knowledge, based upon our review of the list of current stop orders available on the SEC’s website,
that any stop order suspending its effectiveness has been issued or that any proceedings for that purpose are pending before, or threatened by, the SEC and the Registrable
Securities are available for resale under the 1933 Act pursuant to the Registration Statement.

Exhibit B-18

 
  
 
 
 
 
 
 
 
 
This letter shall serve as our standing instruction to you that the shares of Common Stock are freely transferable by the Holders pursuant to the Registration
Statement. You need not require further letters from us to effect any future legend-free issuance or reissuance of shares of Common Stock to the Holders as contemplated by the
Company’s Irrevocable Transfer Agent Instructions dated [●], 2018, provided at the time of such reissuance, the Company has not otherwise notified you that the Registration
Statement is unavailable for the resale of the Registrable Securities.

CC: [LIST NAMES OF HOLDERS]

Very truly yours,

[ISSUER’S COUNSEL]

By:

Exhibit B-19

 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
      
 
 
 
 
 
 
 
 
 
 
 
SELLING STOCKHOLDERS

The shares of common stock being offered by the selling shareholders are those issuable upon conversion of the secured convertible notes. We are registering
the shares of common stock in order to permit the selling shareholders to. offer the shares for resale from time to time. [Except for the ownership of the secured convertible notes,
the selling shareholders have not had any material relationship with us within the past three years.]

The table below lists the selling shareholders and other information regarding the beneficial ownership of the shares of common stock by each of the selling
shareholders. The second column lists the number of shares of common stock beneficially owned by each selling shareholder, based on its ownership of the shares of the secured
convertible notes, as of ________, 2018, assuming conversion of all secured convertible notes held by the selling shareholders on that date, without regard to any limitations on
conversions and/or redemptions of the secured convertible notes.

The third column lists the shares of common stock being offered by this prospectus by the selling shareholders.

The fourth column assumes the sale of all of the shares offered by the selling shareholders pursuant to this prospectus.

Exhibit B-20

 
  
 
 
 
 
 
 
 
PLAN OF DISTRIBUTION

We are registering the shares of common stock issuable upon conversion of the secured convertible notes to permit the resale of these shares of common stock
by the holders of the secured convertible notes from time to time after the date of this prospectus. We will not receive any of the proceeds from the sale by the selling shareholders
of the shares of common stock. We will bear all fees and expenses incident to our obligation to register the shares of common stock.

The selling shareholders may sell all or a portion of the shares of common stock beneficially owned by them and offered hereby from time to time directly or
through  one  or  more  underwriters,  broker-dealers  or  agents.  If  the  shares  of  common  stock  are  sold  through  underwriters  or  broker-dealers,  the  selling  shareholders  will  be
responsible for underwriting discounts or commissions or agent’s commissions. The shares of common stock may be sold in one or more transactions at fixed prices, at prevailing
market prices at the time of the sale, at varying prices determined at the time of sale, or at negotiated prices. These sales may be effected in transactions, which may involve crosses
or block transactions,

·

·

·

·

·

·

·

·

·

·

·

on any national securities exchange or quotation service on which the securities may be listed or quoted at the time of sale;

in the over-the-counter market;

in transactions otherwise than on these exchanges or systems or in the over-the-counter market;

through the writing of options, whether such options are listed on an options exchange or otherwise;

ordinary brokerage transactions and transactions in which the broker-dealer solicits purchasers;

block trades in which the broker-dealer will attempt to sell the shares as agent but may position and resell a portion of the block as principal to facilitate the
transaction;

purchases by a broker-dealer as principal and resale by the broker-dealer for its account;

an exchange distribution in accordance with the rules of the applicable exchange;

privately negotiated transactions;

short sales;

sales pursuant to Rule 144;

Exhibit B-21

 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
·

·

·

broker-dealers may agree with the selling shareholders to sell a specified number of such shares at a stipulated price per share;

a combination of any such methods of sale; and

any other method permitted pursuant to applicable law.

If the selling shareholders effect such transactions by selling shares of common stock to or through underwriters, broker-dealers or agents, such underwriters,
broker-dealers or agents may receive commissions in the form of discounts, concessions or commissions from the selling shareholders or commissions from purchasers of the
shares of common stock for whom they may act as agent or to whom they may sell as principal (which discounts, concessions or commissions as to particular underwriters, broker-
dealers or agents may be in excess of those customary in the types of transactions involved). In connection with sales of the shares of common stock or otherwise, the selling
shareholders may enter into hedging transactions with broker-dealers, which may in turn engage in short sales of the shares of common stock in the course of hedging in positions
they assume. The selling shareholders may also sell shares of common stock short and deliver shares of common stock covered by this prospectus to close out short positions
and to return borrowed shares in connection with such short sales. The selling shareholders may also loan or pledge shares of common stock to broker-dealers that in turn may sell
such shares.

The selling shareholders may pledge or grant a security interest in some or all of the secured convertible notes or shares of common stock owned by them and, if
they default in the performance of their secured obligations, the pledgees or secured parties may offer and sell the shares of common stock from time to time pursuant to this
prospectus or any amendment to this prospectus under Rule 424(b)(3) or other applicable provision of the Securities Act of 1933, as amended, amending, if necessary, the list of
selling shareholders to include the pledgee, transferee or other successors in interest as selling shareholders under this prospectus. The selling shareholders also may transfer and
donate the shares of common stock in other circumstances in which case the transferees, donees, pledgees or other successors in interest will be the selling beneficial owners for
purposes of this prospectus.

The selling shareholders and any broker-dealer participating in the distribution of the shares of common stock may be deemed to be “underwriters” within the
meaning of the Securities Act, and any commission paid, or any discounts or concessions allowed to, any such broker-dealer may be deemed to be underwriting commissions or
discounts under the Securities Act. At the time a particular offering of the shares of common stock is made, a prospectus supplement, if required, will be distributed which will set
forth the aggregate amount of shares of common stock being offered and the terms of the offering, including the name or names of any broker-dealers or agents, any discounts,
commissions and other terms constituting compensation from the selling shareholders and any discounts, commissions or concessions allowed or reallowed or paid to broker-
dealers.

Under the securities laws of some states, the shares of common stock may be sold in such states only through registered or licensed brokers or dealers. In
addition, in some states the shares of common stock may not be sold unless such shares have been registered or qualified for sale in such state or an exemption from registration or
qualification is available and is complied with.

Exhibit B-22

 
  
 
 
 
 
 
 
 
 
 
of which this prospectus forms a part.

There can be no assurance that any selling shareholder will sell any or all of the shares of common stock registered pursuant to the shelf registration statement,

The selling shareholders and any other person participating in such distribution will be subject to applicable provisions of the Securities Exchange Act of 1934,
as amended, and the rules and regulations thereunder, including, without limitation, Regulation M of the Exchange Act, which may limit the timing of purchases and sales of any of
the shares of common stock by the selling shareholders and any other participating person. Regulation M may also restrict the ability of any person engaged in the distribution of
the shares of common stock to engage in market-making activities with respect to the shares of common stock. All of the foregoing may affect the marketability of the shares of
common stock and the ability of any person or entity to engage in market-making activities with respect to the shares of common stock.

We will pay all expenses of the registration of the shares of common stock pursuant to the registration rights agreement, estimated to be $[_______] in total,
including, without limitation, Securities and Exchange Commission filing fees and expenses of compliance with state securities or “blue sky” laws; provided, however, that a selling
shareholder will pay all underwriting discounts and selling commissions, if any. We will indemnify the selling shareholders against liabilities, including some liabilities under the
Securities Act, in accordance with the registration rights agreements, or the selling shareholders will be entitled to contribution. We may be indemnified by the selling shareholders
against civil liabilities, including liabilities under the Securities Act, that may arise from any written information furnished to us by the selling shareholder specifically for use in this
prospectus, in accordance with the related registration rights agreement, or we may be entitled to contribution.

persons other than our affiliates.

Once sold under the shelf registration statement, of which this prospectus forms a part, the shares of common stock will be freely tradable in the hands of

Exhibit B-23

 
  
 
 
 
 
 
 
Exhibit C

Form of Security Agreement of the Company

 
  
 
 
 
FORM OF

SECURITY AGREEMENT

dated ____________, 2018

by

the Grantor referred to herein

as Grantor

to

Delaware Trust Company

as Collateral Agent

 
 
 
 
 
 
 
 
 
 
 
 
 
TABLE OF CONTENTS

  PAGE

Section 1.

Section 2.

Section 3.

Section 4.

Section 5.

Section 6.

Section 7.

Section 8.

Section 9.

Section 10.

Section 11.

Section 12.

Section 13.

Section 14.

Section 15.

Section 16.

Section 17.

Section 18.

Section 19.

Section 20.

Section 21.

Section 22.

Section 23.

Grant of Security

Security for Obligations

Grantor Remains Liable

Delivery and Control of Security Collateral

Maintaining the Account Collateral

Representations and Warranties

Further Assurances

As to Equipment and Inventory

As to Books and Records

Insurance

Post-Closing Changes; Collections on Assigned Agreements, Receivables and Related Contracts

As to Intellectual Property Collateral

Voting Rights; Dividends; Etc.

As to Letter-of-Credit Rights

Commercial Tort Claims

Transfers and Other Liens; Additional Shares

Collateral Agent Appointed Attorney in Fact

Collateral Agent May Perform

The Collateral Agent’s Duties

Remedies

Indemnity and Expenses

Amendments; Waivers; Additional Grantors; Etc.

Notices, Etc.

2

2

5

6

6

7

7

10

11

11

12

12

13

13

14

15

15

15

16

16

17

19

19

20

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Section 24.

Section 25.

Section 26.

Section 27.

Schedules:

Schedule I
Schedule II
Schedule III
Schedule IV
Schedule V
Schedule VI
Schedule VII
Schedule VIII
Schedule IX
Schedule X
Schedule XI

Exhibits:

Exhibit A
Exhibit B

Continuing Security Interest

Release; Termination.

Execution in Counterparts

Governing Law; Jurisdiction; Waiver of Jury Trial, Etc.

20

20

20

21

-
-
-
-
-
-
-
-
-
-

-
-

Investment Property
Deposit Accounts
Assigned Agreements
Intellectual Property
Commercial Tort Claims
Location, Chief Executive Office, Type of Organization, Jurisdiction of Organization and Organizational Identification Number
Changes in Name, Location, Etc.
Locations of Equipment, Inventory and Books and Records
Letters of Credit
Permitted Liens
Excluded Assets

Form of Intellectual Property Security Agreement
Form of IP Security Agreement Supplement

3

 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
SECURITY AGREEMENT

SECURITY AGREEMENT (as amended, supplemented, amended and restated or otherwise modified from time to time, this “Agreement”) dated _____________,
2018 made by APPLIED DNA SCIENCES, INC., a Delaware corporation with headquarters located at 50 Health Sciences Drive, Stony Brook, New York 11790 (the “ Grantor”), in
favor of DELAWARE TRUST COMPANY, a Delaware corporation, as collateral agent (together with any successor collateral agent, in such capacity, the “ Collateral Agent”) for
the benefit of the investors listed on the Schedule of Buyers (each a “Buyer” and collectively, the “Buyers”; the  Buyers and the  Collateral Agent are collectively, with their
successors and assigns, the “Secured Parties”)) set forth in the Securities Purchase Agreement, dated as of August 31, 2018 (as amended, amended and restated, supplemented or
otherwise modified from time to time) and the other Secured Parties (the “Securities Purchase Agreement”).

PRELIMINARY STATEMENTS.

WHEREAS, the Grantor and each Buyer are parties to the Securities Purchase Agreement, pursuant to which the Grantor shall be required to sell, and the Buyers
shall purchase or have rights to purchase, on a several and not joint basis the principal amount of the Notes issued pursuant thereto (as such Notes may be amended, amended
and restated, supplemented or otherwise modified from time to time, the “Notes”); and

WHEREAS, it is a condition precedent to the Buyers purchasing the Notes pursuant to the Securities Purchase Agreement that the Grantor shall have executed
and delivered to the Collateral Agent this Agreement providing for the grant to the Collateral Agent for the benefit of the Secured Parties of a security interest in all of the personal
property of the Grantor to secure all of the Grantor’s Obligations (as defined below) under the Securities Purchase Agreement, the Notes and the other Transaction Documents;
and

WHEREAS, the Grantor, the Buyers and the Collateral Agent are parties to that certain Collateral Agency Agreement dated as of the date hereof (as amended,

supplemented, amended and restated or otherwise modified from time to time, the “Collateral Agency Agreement”); and

WHEREAS,  capitalized  terms  used  herein  and  not  otherwise  defined  in  this Agreement  are  used  in  this Agreement  as  defined  in  the  Securities  Purchase
Agreement. Further, unless otherwise defined in this Agreement or in the Securities Purchase Agreement, terms defined in  Article 8 or 9 of the UCC (as defined below) are used in
this Agreement as such terms are defined in such Article 8 or 9. “UCC” means the Uniform Commercial Code as in effect from time to time in the State of New York; provided that, if
perfection or the effect of perfection or non-perfection or the priority of the security interest in any  Collateral is governed by the  Uniform  Commercial  Code as in effect in a
jurisdiction other than the State of New York, “UCC” means the Uniform Commercial Code as in effect from time to time in such other jurisdiction for purposes of the provisions
hereof relating to such perfection, effect of perfection or non-perfection or priority.

 
 
 
 
 
 
 
 
 
 
Grantor hereby agrees with the Collateral Agent for the ratable benefit of the Secured Parties as follows:

NOW, THEREFORE, in consideration of the premises and in order to induce the Buyers to purchase the Notes under the Securities Purchase Agreement, the

Section 1.           Grant of Security. Grantor hereby grants to the Collateral Agent, for the ratable benefit of the Secured Parties, a security interest in all of Grantor’s
tangible and intangible assets, whether real or personal property, now or hereafter acquired, including without limitation all of  Grantor’s right, title and interest in and to the
following (collectively, the “Collateral”):

(a)         all equipment in all of its forms, including, without limitation, all machinery, tools, motor vehicles, vessels, aircraft, furniture and fixtures, and all
parts thereof and all accessions thereto, including, without limitation, computer programs and supporting information that constitute equipment within the meaning of the UCC
(any and all such property being the “Equipment”);

(b)         all inventory in all of its forms, including, without limitation, (i) all raw materials, work in process, finished goods and materials used or consumed
in the manufacture, production, preparation or shipping thereof, (ii) goods in which Grantor has an interest in mass or a joint or other interest or right of any kind (including,
without limitation, goods in which Grantor has an interest or right as consignee) and (iii) goods that are returned to or repossessed or stopped in transit by Grantor), and all
accessions thereto and products thereof and documents therefor, including, without limitation, computer programs and supporting information that constitute inventory within the
meaning of the UCC (any and all such property being the “Inventory”);

(c)         all accounts (including, without limitation, health-care-insurance receivables), chattel paper (including, without limitation, tangible chattel paper
and  electronic  chattel  paper),  instruments  (including,  without  limitation,  promissory  notes),  deposit  accounts  (other  than  Excluded Accounts  (defined  below)),  letter-of-credit
rights, general intangibles (including, without limitation, payment intangibles) and other Obligations of any kind, whether or not arising out of or in connection with the sale or
lease of goods or the rendering of services and whether or not earned by performance, and all rights now or hereafter existing in and to all supporting Obligations and in and to all
security agreements, mortgages, Liens, leases, letters of credit and other contracts securing or otherwise relating to the foregoing property (any and all of such accounts, chattel
paper,  instruments,  deposit  accounts,  letter-of-credit  rights,  general  intangibles  and  other  Obligations,  to  the  extent  not  referred  to  in clause  (d),  (e)  or (f)  below,  being  the
“Receivables,” and any and all such supporting Obligations, security agreements, mortgages, Liens, leases, letters of credit and other contracts being the “Related Contracts”);

(d)         the following (the “Security Collateral”):

(i)          the all of the shares of capital stock of (or other ownership or profit interests in, including partnership, membership or trust interests) in
any entity (“Equity Interests”) listed on Part I of Schedule I (Investment Property) hereto, and the certificates, if any, representing such additional shares or other Equity Interests,
and all dividends, distributions, return of capital, cash, instruments and other property from time to time received, receivable or otherwise distributed in respect of or in exchange
for any or all of such shares or other Equity Interests and all warrants, rights or options issued thereon or with respect thereto;

Exhibit C-2

 
  
 
 
 
 
 
 
 
 
 
(ii)         the indebtedness listed on Part II of Schedule I (Investment Property) hereto and all additional indebtedness now or from time to time
owed to Grantor (such indebtedness being the “Pledged Debt”) and the instruments, if any, evidencing such indebtedness, and all interest, cash, instruments and other property
from time to time received, receivable or otherwise distributed in respect of or in exchange for any or all of such indebtedness; and

(iii)                all  other  investment  property  (including,  without  limitation,  all  (A)  securities,  whether  certificated  or  uncertificated,  (B)  security
entitlements, (C) securities accounts, (D) commodity contracts and (E) commodity accounts) in which Grantor has now, or acquires from time to time hereafter, any right, title or
interest in any manner, and the certificates or instruments, if any, representing or evidencing such investment property, and all dividends, distributions, return of capital, interest,
cash, instruments and other property from time to time received, receivable or otherwise distributed in respect of or in exchange for any or all of such investment property and all
warrants, rights or options issued thereon or with respect thereto;

(e)         each of the agreements listed on Schedule III (Assigned Agreements) attached hereto, in each case as such agreements may be amended,
restated, amended and restated, supplemented or otherwise modified from time to time (collectively, the “Assigned Agreements ”), including, without limitation, (w) all rights of
Grantor to receive moneys due and to become due under or pursuant to the Assigned Agreements, (x) all rights of Grantor to receive proceeds of any insurance, indemnity,
warranty or guaranty with respect to the Assigned Agreements, (y) claims of Grantor for damages arising out of or for breach of or default under the Assigned Agreements and
(z) the right of Grantor to terminate the Assigned Agreements, to perform thereunder and to compel performance and otherwise exercise all remedies thereunder (all such Collateral
being the “Agreement Collateral”);

(f)          the following (collectively, the “Account Collateral”):

thereto (including, without limitation, all cash equivalents), and all certificates and instruments, if any, from time to time representing or evidencing the Deposit Accounts;

(i)          the deposit accounts listed on Schedule II (Deposit Accounts) hereto and all funds and financial assets from time to time credited

Collateral Agent for or on behalf of Grantor in substitution for or in addition to any or all of the then existing Account Collateral; and

(ii)         all promissory notes, certificates of deposit, checks and other instruments from time to time delivered to or otherwise possessed by the

in respect of or in exchange for any or all of the then existing Account Collateral;

(iii)        all interest, dividends, distributions, cash, instruments and other property from time to time received, receivable or otherwise distributed

Exhibit C-3

 
  
 
 
 
 
 
 
 
 
 
(g)         the following (collectively, the “Intellectual Property Collateral”):

improvements thereto (“Patents”);

(i)          all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all

(ii)         all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and
other source identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent
that, and solely during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under
applicable federal law), together, in each case, with the goodwill symbolized thereby (“Trademarks”);

content thereof, whether registered or unregistered (“Copyrights”);

(iii)        all copyrights, including, without limitation, copyrights in  Computer  Software (as hereinafter defined), internet web sites and the

(iv)        all computer software, programs and databases (including, without limitation, source code, object code and all related applications and
data files), firmware and documentation and materials relating thereto, together with any and all maintenance rights, service rights, programming rights, hosting rights, test rights,
improvement rights, renewal rights and indemnification rights and any substitutions, replacements, improvements, error corrections, updates and new versions of any of the
foregoing (“Computer Software”);

(v)         all confidential and proprietary information, including, without limitation, know-how, trade secrets, manufacturing and production
processes and techniques, inventions, research and development information, databases and data, including, without limitation, technical data, financial, marketing and business
data, pricing and cost information, business and marketing plans and customer and supplier lists and information (collectively, “Trade Secrets”), and all other intellectual, industrial
and intangible property of any type, including, without limitation, industrial designs and mask works;

(vi)                all  registrations  and  applications  for  registration  for  any  of  the  foregoing,  including,  without  limitation,  those  registrations  and
applications for registration set forth in Schedule IV (Intellectual Property) attached hereto, together with all reissues, divisions, continuations, continuations-in-part, extensions,
renewals and reexaminations thereof;

corresponding thereto throughout the world and all other rights of any kind whatsoever of Grantor accruing thereunder or pertaining thereto;

(vii)       all tangible embodiments of the foregoing, all rights in the foregoing provided by international treaties or conventions, all rights

(viii)      all agreements, permits, consents, orders and franchises relating to the license, development, use or disclosure of any of the foregoing
to which Grantor, now or hereafter, is a party or a beneficiary, including, without limitation, the agreements set forth in  Schedule IV (Intellectual Property) attached hereto, (“IP
Agreements”); and

Exhibit C-4

 
  
 
 
 
 
 
 
 
 
 
 
 
misuse or breach with respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages;

(ix)         any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation,

which the Grantors have complied with the requirements of Section 15, the “Commercial Tort Claims Collateral”);

(h)         the commercial tort claims described in Schedule V (Commercial Tort Claims) attached hereto (together with any commercial tort claims as to

Grantor pertaining to any of the Collateral; and

(i)          all books and records (including, without limitation, customer lists, credit files, printouts and other computer output materials and records) of

(j)                    all  proceeds  of,  collateral  for,  income,  royalties  and  other  payments  now  or  hereafter  due  and  payable  with  respect  to,  and  supporting
Obligations relating to, any and all of the Collateral (including, without limitation, proceeds, collateral and supporting Obligations that constitute property of the types described in
clauses (a) through (i) of this Section 1) and, to the extent not otherwise included, all (A) payments under insurance (whether or not the Collateral Agent is the loss payee thereof),
or any indemnity, warranty or guaranty, payable by reason of loss or damage to or otherwise with respect to any of the foregoing Collateral, and (B) cash;

provided that the term “Collateral” shall at all times exclude all Excluded Assets. “Excluded Assets” means all assets listed on Schedule XI (Excluded Assets) attached hereto.

Section 2.           Security for Obligations. This Agreement and the Collateral granted hereunder secures, in the case of Grantor, the payment of all Obligations now
or hereafter existing, whether direct or indirect, absolute or contingent, and whether for principal, reimbursement Obligations, interest, fees, premiums, penalties, indemnifications,
contract causes of action, costs, expenses or otherwise (all such Obligations, the “Secured Obligations”). Without limiting the generality of the foregoing, this Agreement secures
the payment of all amounts that constitute part of the Secured Obligations and would be owed by Grantor to any Secured Party under the Transaction Documents but for the fact
that they are unenforceable or not allowable due to the existence of a bankruptcy, reorganization or similar proceeding involving the Grantor. The term “ Obligations” shall mean for
so  long  as  the  Notes  are  outstanding  the  payment  by  the  Company,  as  and  when  due  and  payable  (by  scheduled  maturity,  required  prepayment,  acceleration,  demand  or
otherwise), of all amounts from time to time owing by it in respect of the Securities Purchase Agreement, the Notes, the Collateral Agency Agreement and the other Transaction
Documents, including, without limitation, (A) all principal of and interest on the  Notes (including, without limitation, all interest that accrues after the commencement of any
insolvency proceeding of the Grantor, whether or not the payment of such interest is unenforceable or is not allowable due to the existence of such insolvency proceeding), and
(B) all fees, commissions, expense reimbursements, indemnifications and all other amounts due or to become due under any of the Transaction Documents.

Exhibit C-5

 
  
 
 
 
 
 
 
 
 
Section  3.            Grantor Remains Liable. Anything herein to the contrary notwithstanding, (a) Grantor shall remain liable under the contracts and agreements
included in the Collateral to the extent set forth therein to perform all of its duties and Obligations thereunder to the same extent as if this Agreement had not been executed, (b) the
exercise by the Collateral Agent of any of the rights hereunder shall not release Grantor from any of its duties or Obligations under the contracts and agreements included in the
Collateral and (c) no Secured Party shall have any obligation or liability under the contracts and agreements included in the Collateral by reason of this Agreement or any other
Transaction Document, nor shall any Secured Party be obligated to perform any of the Secured Obligations or duties of any Grantor thereunder or to take any action to collect or
enforce any claim for payment assigned hereunder.

Section 4.            Delivery and Control of Security Collateral.

(a)         All certificates or instruments representing or evidencing Security Collateral shall be delivered to and held by or on behalf of the Collateral
Agent pursuant hereto and shall be in suitable form for transfer by delivery, or shall be accompanied by duly executed instruments of transfer or assignment in blank, all in form
and  substance  reasonably  satisfactory  to  the  Secured  Parties.  The  Collateral Agent  shall  have  the  right  at  any  time  to  exchange  certificates  or  instruments  representing  or
evidencing Security Collateral for certificates or instruments of smaller or larger denominations.

(b)         With respect to any Security Collateral that constitutes an uncertificated security, the Grantor will cause the issuer either (i) to register the
Collateral Agent as the registered owner of such security or (ii) to agree with Grantor and the Collateral Agent that such issuer will comply with instructions with respect to such
security originated by the Collateral Agent without further consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (such
agreement being an “Uncertificated Security Control Agreement”).

(c)         With respect to any Security Collateral that constitutes a security entitlement as to which the financial institution acting as Collateral Agent
hereunder is not the securities intermediary, Grantor will cause the securities intermediary with respect to such security entitlement either (i) to identify in its records the Collateral
Agent as the entitlement holder thereof or (ii) to agree with Grantor and the Collateral Agent that such securities intermediary will comply with entitlement orders originated by the
Collateral Agent without further consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (a “ Securities Account Control
Agreement”).

(d)         The Collateral Agent shall have the right, at any time and without notice to any Grantor, to endorse, assign or otherwise transfer to or to register
in the name of the Collateral Agent or any of its nominees or endorse for negotiation any or all of the Security Collateral, without any indication that such Security Collateral is
subject to the security interest hereunder, subject only to the revocable rights specified in Section 13(a).

Collateral is subject to the security interest granted hereunder.

(e)         Upon the request of the Collateral Agent, Grantor will notify each issuer of Security Collateral granted by it hereunder that such Security

Exhibit C-6

 
 
 
 
 
 
 
 
 
 
 
Section 5.           Maintaining the Account Collateral. So long as the Secured Obligations remain outstanding and unpaid:

(a)         Grantor will maintain deposit accounts only with a bank or other depository institution (a “Pledged Account Bank”) that has agreed (or will
agree) with Grantor and the Collateral Agent to comply with instructions originated by the Collateral Agent directing the disposition of funds in such deposit account without the
further consent of Grantor, such agreement to be in form and substance reasonably satisfactory to the Secured Parties (a “Deposit Account Control Agreement ”). As a condition
to  the  establishment  and  maintenance  of  deposit  accounts  with  any  such  bank  or  other  depository  institution,  Grantor  shall  have  entered  into  a  Deposit Account  Control
Agreement with such Pledged Account Bank, except with respect to Excluded Accounts (defined below).

Deposit Accounts, to satisfy the Secured Obligations under the Transaction Documents only if an Event of Default shall have occurred and be continuing.

(b)         The Collateral Agent may, without notice to, or consent from, Grantor, give such instructions, transfer, or direct the transfer of, funds from the

payroll, bonuses, other compensation and related expenses and (b) any accounts held outside of the United States of America.

(c)         For the purposes hereof, “Excluded Accounts” means (a) any deposit account that is used solely for escrow, tax, tax withholding, payment of

Section 6.             Representations and Warranties. Grantor represents and warrants as follows:

(a)         As of the Effective Date, Grantor’s exact legal name, location of chief executive office, type of organization, jurisdiction of organization and
organizational identification number (if any) are set forth in Schedule VI (Location, Chief Executive Office, Type of Organization, Jurisdiction of Organization and Organizational
Identification Number); attached hereto. Grantor has no trade names other than as listed on Schedule VI (Location, Chief Executive Office, Type of Organization, Jurisdiction of
Organization and Organizational Identification Number) attached hereto. Within the five years preceding the Effective Date, Grantor has not changed its name, location of its
chief executive office, type of organization, jurisdiction of organization or organizational identification number from those set forth in Schedule VI  (Location,  Chief  Executive
Office, Type of Organization, Jurisdiction of Organization and Organizational Identification Number) attached hereto except as set forth in Schedule VII (Changes in Name,
Location, Etc.) attached hereto.

(b)         Grantor is the legal and beneficial owner of the Collateral granted or purported to be granted by it free and clear of any Lien, claim, option or
right of others, except for the security interest created under this Agreement or permitted hereunder and listed on Schedule X (Permitted Liens). No effective financing statement or
other instrument similar in effect covering all or any part of such Collateral or listing Grantor or any trade name of Grantor as debtor is on file in any recording office, except such as
may have been filed in favor of the Collateral Agent relating to the Transaction Documents or as otherwise permitted under the Securities Purchase Agreement.

Exhibit C-7

 
  
 
 
 
 
 
 
 
 
 
(c)         All of the Equipment and Inventory of Grantor is located at the places specified therefor in Schedule VIII (Locations of Equipment, Inventory
and Books and Records) attached hereto or at another location as to which Grantor has complied with the requirements of Section 8(a). Grantor has exclusive possession and
control of its Equipment and Inventory.

(d)         All books and records related to the Collateral are located at the places specified therefor in Schedule VIII (Locations of Equipment, Inventory
and  Books  and  Records)  attached  hereto.  Grantor  agrees  to  obtain  a  lien  waiver  and  access  agreement  in  favor  of  the  Collateral Agent,  in  form  and  substance  reasonably
satisfactory to the Secured Parties, with respect to each location in which any books and records are stored. Grantor further agrees to deliver a fully-executed copy of such lien
waiver and access agreement to the Collateral Agent prior to the delivery of such books and records to any other location.

Collateral Agent.

(e)         None of the Receivables or Agreement Collateral is evidenced by a promissory note or other instrument that has not been delivered to the

(f)          If Grantor is an issuer of Security Collateral, Grantor confirms that it has received notice of the security interest granted hereunder.

(g)         The Pledged Equity pledged by Grantor hereunder (if any) has been duly authorized and validly issued and is fully paid and non-assessable.
The Pledged Debt issued by Grantor and pledged by another Grantor hereunder has been duly authorized, authenticated or issued and delivered, is the valid and legally binding
obligation of the issuers thereof and is evidenced by one or more promissory notes (which promissory notes have been delivered to the Collateral Agent).

(h)         The Pledged Equity pledged by Grantor constitutes the percentage of the issued and outstanding Equity Interests of the issuers thereof
indicated on Part I of Schedule I (Investment Property) attached hereto. The Pledged Debt constitutes all of the outstanding indebtedness owed to Grantor by the issuers thereof
and is outstanding in the principal amount indicated, Part II of Schedule I (Investment Property) attached hereto, as of the date hereof and is not in default.

Property).

(i)          Grantor has no investment property, other than the investment property listed on Schedule I (Pledged Equity; Pledged Debt; Investment

(j)          Grantor shall use best efforts to deliver to the Collateral Agent a consent in form and substance reasonably satisfactory to the Secured Parties
from each party to the Assigned Agreements to which the Borrower is a party to the grant of a security interest in such Assigned Agreement pursuant to this Agreement (which
by its terms does not require any such consent or for which a consent was previously obtained).

and additional deposit accounts as to which Grantor has complied (or as the case may be, will comply) with the applicable requirements of Section 5.

(k)         Grantor has no deposit accounts other than the Deposit Accounts listed on Schedule II (Deposit Accounts) attached hereto, Excluded Accounts

Exhibit C-8

 
  
 
 
 
 
 
 
 
 
 
 
 
attached hereto and additional letters of credit as to which Grantor has complied with the requirements of Section 14.

(l)          Grantor is not a beneficiary or assignee under any letter of credit, other than the letters of credit described in Schedule IX (Letters of Credit)

(m)        This Agreement creates in favor of the Collateral Agent for the benefit of the Secured Parties a valid first priority security interest in the
Collateral granted by Grantor, securing the payment of the Secured Obligations; such security interest is subject in priority only to the Permitted Liens and the recording of all
filings and other actions (including, without limitation, (A) actions necessary to obtain control of Collateral as provided in Sections 9-104, 9-105, 9-106 and 9-107 of the UCC and (B)
actions necessary to perfect the Collateral Agent’s security interest with respect to Collateral evidenced by a certificate of title) necessary to perfect the security interest in the
Collateral granted by Grantor have been duly made or taken and are in full force and effect on and after the date hereof.

(n)         No authorization or approval or other action by, and no notice to or filing with, any governmental authority or regulatory body or any other third
party is required for (i) the grant by Grantor of the security interest granted hereunder or for the execution, delivery or performance of this Agreement by Grantor, (ii) the perfection
or maintenance of the security interest created hereunder (including the first priority nature of such security interest), except for the filing of financing and continuation statements
under the UCC, which financing statements shall have been duly filed within 45 days of the Closing, as defined in the Securities Purchase Agreement and, upon filing, shall be in
full force and effect, the recordation of the Intellectual Property Security Agreements referred to in Section 12(c) with the U.S. Patent and Trademark Office and the U.S. Copyright
Office, and the actions described in Section 4 with respect to the Security Collateral, which actions have been taken and are in full force and effect, or (iii) the exercise by the
Collateral Agent of its voting or other rights provided for in this Agreement or the remedies in respect of the Collateral pursuant to this Agreement, except as may be required in
connection with the disposition of any portion of the Security Collateral by laws affecting the offering and sale of securities generally.

(o)         The Inventory that has been produced or distributed by Grantor has been produced in material compliance with all requirements of applicable

law.

(p)         As to itself and its Intellectual Property Collateral:

(i)          The operation of Grantor’s business as currently conducted or as contemplated to be conducted and the use of the Intellectual
Property Collateral in connection therewith, to the best of Grantor’s knowledge, do not conflict with, infringe, misappropriate, dilute, misuse or otherwise violate the intellectual
property rights of any third party.

Intellectual Property Collateral subject only to the terms of the IP Agreements.

(ii)         Grantor is the exclusive owner of all right, title and interest in and to the Intellectual Property Collateral, and is entitled to use all

Exhibit C-9

 
  
 
 
 
 
 
 
 
 
 
applications, domain names, trademark registrations and applications, copyright registrations and applications and IP Agreements owned by Grantor as of the date hereof.

(iii)        The Intellectual Property Collateral set forth on Schedule IV (Intellectual Property) attached hereto includes all of the patents, patent

(iv)        The Intellectual Property Collateral is subsisting and has not been adjudged invalid or unenforceable in whole or in part, and to the
best of Grantor’s knowledge, is valid and enforceable. Grantor is not aware of any uses of any item of Intellectual Property Collateral that could be expected to lead to such item
becoming invalid or unenforceable.

any of the Intellectual Property Collateral.

(v)         The consummation of the transactions contemplated by the Transaction Documents will not result in the termination or impairment of

commercial tort claims as to which Grantor has complied with the requirements of Section 15.

(q)                    Grantor  has  no  commercial  tort  claims  other  than  those  listed  in Schedule  V  (Commercial  Tort  Claims)  attached  hereto  and  additional

Section 7.            Further Assurances.

(a)         Grantor agrees that from time to time, at the expense of Grantor, Grantor will promptly execute and deliver, or otherwise authenticate, all further
instruments and documents, and take all further action that may be necessary or desirable, or that the Collateral Agent may request, in order to perfect and protect any pledge or
security interest granted or purported to be granted by Grantor hereunder or to enable the Collateral Agent to exercise and enforce its rights and remedies hereunder with respect
to any Collateral of Grantor. Without limiting the generality of the foregoing, Grantor will promptly with respect to Collateral of Grantor: (i) mark conspicuously each document
included in Inventory, each chattel paper included in Receivables, each Related Contract and, at the request of the Collateral Agent, each of its records pertaining to such Collateral
with a legend, in form and substance reasonably satisfactory to the  Secured  Parties, indicating that such document, chattel paper,  Related  Contract, Assigned Agreement or
Collateral is subject to the security interest granted hereby; (ii) if any such Collateral shall be evidenced by a certificate, promissory note or other instrument or chattel paper,
deliver and pledge to the Collateral Agent hereunder such certificate, note or instrument or chattel paper duly indorsed and accompanied by duly executed instruments of transfer
or assignment, all in form and substance reasonably satisfactory to the Secured Parties; (iii) file such financing or continuation statements, or amendments thereto, and such other
instruments or notices, as may be necessary or desirable, or as the Collateral Agent may request, in order to perfect and preserve the security interest granted or purported to be
granted by Grantor hereunder; (iv) take all action to ensure that the Collateral Agent’s security interest is noted on any certificate of title related to any Collateral evidenced by a
certificate  of  title;  (v)  to  cause  the  relevant  depository  institutions,  banks,  financial  intermediaries,  securities  intermediaries  and  issuers  to  execute  and  deliver  such  Deposit
Account Control Agreements, Uncertificated Security Control Agreements, Securities Account Control Agreements and other control agreements, as may be necessary or as the
Collateral Agent may from time to time require; and (vi) deliver to the Collateral Agent evidence that all other actions that the Collateral Agent may deem reasonably necessary or
desirable in order to perfect and protect the security interest granted or purported to be granted by Grantor under this Agreement has been taken.

Exhibit C-10

 
 
 
 
 
 
 
 
 
 
(b)         Grantor hereby authorizes the Secured Parties to file one or more financing or continuation statements, and amendments thereto, including,
without limitation, one or more financing statements indicating that such financing statements cover all assets or all personal property (or words of similar effect) of Grantor,
regardless of whether any particular asset described in such financing statements falls within the scope of the UCC or the granting clause of this Agreement. A photocopy or other
reproduction of this Agreement shall be sufficient as a financing statement where permitted by law. Grantor ratifies its authorization for the Secured Parties to have filed such
financing statements, continuation statements or amendments filed prior to the date hereof.

Grantor and such other reports in connection with such Collateral as the Secured Parties may reasonably request, all in reasonable detail.

(c)         Grantor will furnish to the Collateral Agent from time to time statements and schedules further identifying and describing the Collateral of

Section 8.            As to Equipment and Inventory.

(a)         Grantor will keep its Equipment and Inventory (other than Inventory sold in the ordinary course of business and Equipment and Inventory in
transit in the ordinary course of business) at the places therefor specified in Section 6(c) or, upon ten (10) Business Days’ prior written notice to the Collateral Agent, at such other
places designated by Grantor in such notice which shall be an approved warehouse as to which a lien waiver and access agreement has been obtained in favor of and delivered to
the Collateral Agent, in form and substance reasonably satisfactory to the Secured Parties.

(b)         Grantor will cause its Equipment to be maintained and preserved in the same condition, repair and working order as when new, ordinary wear
and tear excepted, and will forthwith, or in the case of any loss or damage to any of such Equipment as soon as practicable after the occurrence thereof, make or cause to be made
all repairs, replacements and other improvements in connection therewith that are desirable to such end.

(c)         Grantor will pay promptly when due all property and other taxes, assessments and governmental charges or levies imposed upon, and all claims
(including, without limitation, claims for labor, materials and supplies) against, its Equipment and Inventory. In producing its Inventory, Grantor will comply, in all material respects,
with all requirements of applicable law.

Section 9.            As to Books and Records.

Grantor will keep its books and records at the places therefor specified in Section 6(d) or, upon ten (10) Business Days’ prior written notice to the Collateral Agent, at such
other places designated by Grantor in such notice which shall be an Approved Warehouse as to which a lien waiver and access agreement has been obtained in favor of and
delivered to the Collateral Agent, in form and substance reasonably satisfactory to the Secured Parties.

Exhibit C-11

 
  
 
 
 
 
 
 
 
 
 
 
Section 10.          Insurance.

Grantor  shall  maintain  insurance  (including  property  insurance,  lender  loss  payable  endorsements,  etc.)  in  such  amounts  and  covering  such  risks  as  are  reasonably
acceptable to the to the Secured Parties and are usually carried by companies engaged in similar businesses and owning similar properties in the same general areas in which
Grantor operates, including without limitation, insurance on the Collateral.

Section 11.         Post-Closing Changes; Collections on Assigned Agreements, Receivables and Related Contracts.

(a)         Grantor shall not change its name, type of organization, jurisdiction of organization, organizational identification number or location from those
set forth in Section 6(a) of this Agreement without prior written notice to the Collateral Agent. Grantor will hold and preserve its records relating to the Collateral, including, without
limitation, the Assigned Agreements and Related Contracts, and will permit representatives of the Collateral Agent at any time during normal business hours and upon reasonable
notice to inspect and make abstracts from such records and other documents. If any Grantor does not have an organizational identification number and later obtains one, it will
forthwith notify the Collateral Agent of such organizational identification number.

(b)         Except as otherwise provided in this Section 11, Grantor will continue to collect, at its own expense, all amounts due or to become due to Grantor
under  the Assigned Agreements,  Receivables  and  Related  Contracts.  In  connection  with  such  collections,  Grantor  may  take  such  action  as  Grantor  may  deem  necessary  or
advisable to enforce collection of the Assigned Agreements, Receivables and Related Contracts;  provided, however, that the Collateral Agent shall have the right at any time,
upon the occurrence and during the continuance of an Event of Default, to take any steps it or the other Secured Parties may deem necessary or advisable, including but not
limited to, notifying the obligors under any Assigned Agreements, Receivables and Related Contracts of the assignment of such Assigned Agreements, Receivables and Related
Contracts to the Collateral Agent and directing such obligors to make payment of all amounts due or to become due to Grantor thereunder directly to the Collateral Agent and,
upon such notification and at the expense of Grantor, to enforce collection of any such Assigned Agreements, Receivables and Related Contracts, to adjust, settle or compromise
the amount or payment thereof, in the same manner and to the same extent as  Grantor might have done, and to otherwise exercise all rights  with  respect  to  such Assigned
Agreements, Receivables and Related Contracts, including, without limitation, those set forth set forth in Section 9-607 of the UCC. After receipt by any Grantor of the notice from
the Collateral Agent referred to in the proviso to the preceding sentence, Grantor will not adjust, settle or compromise the amount or payment of any Receivable or amount due on
any Assigned Agreement or  Related  Contract, release wholly or partly any obligor thereof or allow any credit or discount thereon.  No  Grantor will permit or consent to the
subordination of its right to payment under any of the Assigned Agreements, Receivables and Related Contracts to any other indebtedness or Obligations of the obligor thereof.

Exhibit C-12

 
  
 
 
 
 
 
 
 
Section 12.          As to Intellectual Property Collateral.

(a)         No Grantor shall, without the written consent of the Collateral Agent, discontinue use of or otherwise abandon any  Intellectual  Property
Collateral,  or  abandon  any  right  to  file  an  application  for  patent,  trademark,  or  copyright,  unless  Grantor  shall  have  previously  determined  that  such  use  or  the  pursuit  or
maintenance of such Intellectual Property Collateral is no longer desirable in the conduct of Grantor’s business and that the loss thereof could not reasonably be expected to have
a Material Adverse Change.

(b)         Grantor shall use proper statutory notice in connection with its use of each item of its Intellectual Property Collateral. Except as permitted in
Section 12(a) above, Grantor shall not do or permit any act or knowingly omit to do any act whereby any of its Intellectual Property Collateral may lapse or become invalid or
unenforceable or placed in the public domain.

(c)         With respect to its Intellectual Property Collateral, Grantor agrees to execute or otherwise authenticate an agreement, in substantially the form
set forth in Exhibit A hereto or otherwise in form and substance reasonably satisfactory to the Secured Parties (an “Intellectual Property Security Agreement”), for recording the
security interest granted hereunder to the Collateral Agent in such Intellectual Property Collateral with the U.S. Patent and Trademark Office, the U.S. Copyright Office and any
other governmental authorities necessary to perfect the security interest hereunder in such Intellectual Property Collateral.

(d)         Grantor agrees that should it obtain an ownership interest in any item of the type set forth in Section 1(g) that is not on the date hereof a part of
the Intellectual Property Collateral (“After-Acquired Intellectual Property”) (i) the provisions of this Agreement shall automatically apply thereto, and (ii) any such After-Acquired
Intellectual Property and, in the case of trademarks, the goodwill symbolized thereby, shall automatically become part of the Intellectual Property Collateral subject to the terms and
conditions of this Agreement with respect thereto. Grantor shall give prompt written notice to the Collateral Agent identifying the After-Acquired Intellectual Property, and Grantor
shall execute and deliver to the Collateral Agent with such written notice, or otherwise authenticate, an agreement substantially in the form of Exhibit B hereto or otherwise in form
and substance reasonably satisfactory to the Secured Parties (an “IP Security Agreement Supplement”) covering such After-Acquired Intellectual Property, which IP Security
Agreement Supplement shall be recorded with the U.S. Patent and Trademark Office, the U.S. Copyright Office and any other governmental authorities necessary to perfect the
security interest hereunder in such After-Acquired Intellectual Property.

Section 13.          Voting Rights; Dividends; Etc.. (a) So long as no Event of Default shall have occurred and be continuing:

(i)          Grantor shall be entitled to exercise any and all voting and other consensual rights pertaining to the Security Collateral of Grantor or
any part thereof for any purpose; provided, however, that Grantor will not exercise or refrain from exercising any such right if such action would reasonably be expected to have a
material adverse effect on the value of the Security Collateral or any part thereof.

Exhibit C-13

 
  
 
 
 
 
 
 
 
 
 
(ii)         Grantor shall be entitled to receive and retain any and all dividends, interest and other distributions paid in respect of the Security
Collateral of Grantor if and to the extent that the payment thereof is not otherwise prohibited by the terms of the Transaction Documents; provided, however, except as otherwise
provided in the Securities Purchase Agreement, any and all dividends, interest and other distributions paid or payable other than in cash in respect of, and instruments and other
property received, receivable or otherwise distributed in respect of, or in exchange for, any Security Collateral shall be, and shall be forthwith delivered to the Collateral Agent to
hold as, Security Collateral and shall, if received by Grantor, be received in trust for the benefit of the Collateral Agent, be segregated from the other property or funds of Grantor
and be forthwith delivered to the Collateral Agent as Security Collateral in the same form as so received (with any necessary endorsement).

(iii)        The Collateral Agent will execute and deliver (or cause to be executed and delivered) to Grantor all such proxies and other instruments
as Grantor may reasonably request for the purpose of enabling Grantor to exercise the voting and other rights that it is entitled to exercise pursuant to paragraph (i) above and to
receive the dividends or interest payments that it is authorized to receive and retain pursuant to paragraph (ii) above.

(b)         Upon the occurrence and during the continuance of an Event of Default:

(i)          All rights of Grantor (x) to exercise or refrain from exercising the voting and other consensual rights that it would otherwise be entitled
to exercise pursuant to Section 13(a)(i) shall, upon notice to Grantor by the Collateral Agent, cease and (y) to receive the dividends, interest and other distributions that it would
otherwise be authorized to receive and retain pursuant to Section 13(a)(ii) shall automatically cease, and all such rights shall thereupon become vested in the Collateral Agent,
which shall thereupon have the sole right to exercise or refrain from exercising such voting and other consensual rights and to receive and hold as  Security  Collateral such
dividends, interest and other distributions.

(ii)         All dividends, interest and other distributions that are received by any Grantor contrary to the provisions of paragraph (i) of this
Section 13(b) shall be received in trust for the benefit of the Collateral Agent, shall be segregated from other funds of Grantor and shall be forthwith paid over to the Collateral
Agent as Security Collateral in the same form as so received (with any necessary endorsement).

Section 14.          As to Letter-of-Credit Rights.

(a)         Grantor, by granting a security interest in its Receivables consisting of letter-of-credit rights to the Collateral Agent, intends to (and hereby
does) assign to the Collateral Agent its rights (including its contingent rights) to the proceeds of all Related Contracts consisting of letters of credit of which it is or hereafter
becomes a beneficiary or assignee. Grantor will promptly use commercially reasonable efforts to cause the issuer of each letter of credit in favor of Grantor and each nominated
person (if any) with respect thereto to consent to such assignment of the proceeds thereof pursuant to a consent in form and substance reasonably satisfactory to the Secured
Parties and deliver written evidence of such consent to the Collateral Agent.

Exhibit C-14

 
  
 
 
 
 
 
 
 
 
 
(b)          Upon the occurrence of an  Event of  Default,  Grantor will, promptly upon request by the  Collateral Agent, (i) notify (and  Grantor hereby
authorizes the Collateral Agent to notify) the issuer and each nominated person with respect to each of the Related Contracts consisting of letters of credit that the proceeds
thereof have been assigned to the Collateral Agent hereunder and any payments due or to become due in respect thereof are to be made directly to the Collateral Agent or its
designee and (ii) arrange for the Collateral Agent to become the transferee beneficiary of letter of credit.

Section 15.         Commercial Tort Claims. Grantor will promptly give notice to the Collateral Agent of any commercial tort claim that may arise after the date hereof
and will immediately execute or otherwise authenticate a supplement to this Agreement, and otherwise take all necessary action, to subject such commercial tort claim to the first
priority security interest created under this Agreement.

Section 16.          Transfers and Other Liens; Additional Shares.

(a)         Grantor agrees that it will not (i) sell, assign or otherwise dispose of, or grant any option with respect to, any of the Collateral, other than sales,
assignments and other dispositions of Collateral, and options relating to Collateral, permitted under the terms of the Securities Purchase Agreement, or (ii) create or suffer to exist
any Lien upon or with respect to any of the Collateral of Grantor except for the pledge, assignment and security interest created under this Agreement and Liens permitted under
the Securities Purchase Agreement.

(b)         Grantor agrees that it will (i) cause each issuer of the Pledged Equity pledged by Grantor not to issue any Equity Interests or other securities in
addition to or in substitution for the Pledged Equity issued by such issuer, except to Grantor, and (ii) pledge hereunder, immediately upon its acquisition (directly or indirectly)
thereof, any and all additional Equity Interests or other securities.

Section  17.        Collateral Agent Appointed Attorney in Fact . Grantor hereby irrevocably appoints the Collateral Agent as attorney in fact, with full authority in
the place and stead of Grantor and in the name of Grantor or otherwise, from time to time, to take any action and to execute any instrument that the Collateral Agent or the other
Secured Parties may deem necessary or advisable to accomplish the purposes of this Agreement, including, without limitation, upon the occurrence and during the continuance of
an Event of Default, to:

(a)         obtain and adjust insurance required to be paid to the Collateral Agent pursuant to, or in accordance with, Section 9,

respect of any of the Collateral,

(b)         ask for, demand, collect, sue for, recover, compromise, receive and give acquittance and receipts for moneys due and to become due under or in

(c)         receive, indorse and collect any drafts or other instruments, documents and chattel paper, in connection with clause (a) or (b) above, and

Exhibit C-15

 
  
 
 
 
 
 
 
 
 
 
 
 
(d)         file any claims or take any action or institute any proceedings that the Collateral Agent or the other Secured Parties may deem necessary or
desirable for the collection of any of the Collateral or otherwise to enforce compliance with the terms and conditions of any Assigned Agreement or the rights of the Collateral
Agent with respect to any of the Collateral.

18.         Collateral Agent May Perform. If any Grantor fails to perform any agreement contained herein, the  Collateral Agent may, but without any
obligation to do so and without notice, itself perform, or cause performance of, such agreement, and the expenses of the Collateral Agent incurred in connection therewith shall be
payable by Grantor under Section 21.

Section 

Section 19.          The Collateral Agent’s Duties.

(a)         The powers conferred on the Collateral Agent hereunder are solely to protect the Secured Parties’ interest in the Collateral and shall not impose
any duty upon it to exercise any such powers. Except for the safe custody of any Collateral in its possession and the accounting for moneys actually received by it hereunder, the
Collateral Agent shall have no duty as to any Collateral, as to ascertaining or taking action with respect to calls, conversions, exchanges, maturities, tenders or other matters
relative to any Collateral, whether or not any Secured Party has or is deemed to have knowledge of such matters, or as to the taking of any necessary steps to preserve rights
against any parties or any other rights pertaining to any Collateral. The Collateral Agent shall be deemed to have exercised reasonable care in the custody and preservation of any
Collateral in its possession if such Collateral is accorded treatment substantially equal to that which it accords its own property.

(b)         Anything contained herein to the contrary notwithstanding, the Collateral Agent may from time to time, when the Collateral Agent in its
discretion deems it to be necessary or advisable, appoint one or more subagents (each a “Subagent”) for the Collateral Agent hereunder with respect to all or any part of the
Collateral. In the event that the Collateral Agent so appoints any Subagent with respect to any Collateral, (i) the assignment and pledge of such Collateral and the security interest
granted in such Collateral by Grantor hereunder shall be deemed for purposes of this Security Agreement to have been made to such Subagent, in addition to the Collateral Agent,
for the ratable benefit of the Secured Parties, as security for the Secured Obligations of Grantor, (ii) such Subagent shall automatically be vested, in addition to the Collateral Agent,
with all rights, powers, privileges, interests and remedies of the Collateral Agent hereunder with respect to such Collateral, and (iii) the term “Collateral Agent,” when used herein in
relation to any rights, powers, privileges, interests and remedies of the Collateral Agent with respect to such Collateral, shall include such Subagent; provided, however, that no
such Subagent shall be authorized to take any action with respect to any such Collateral unless and except to the extent expressly authorized in writing by the Collateral Agent.

Exhibit C-16

 
 
 
 
 
 
 
 
 
Section 20.          Remedies. If any Event of Default shall have occurred and be continuing:

(a)         The Collateral Agent may exercise in respect of the Collateral, in addition to other rights and remedies provided for herein or otherwise available
to it, all the rights and remedies of a secured party upon default under the UCC (whether or not the UCC applies to the affected Collateral) and also may: (i) require Grantor to, and
Grantor hereby agrees that it will at its expense and upon request of the Collateral Agent forthwith, to the extent commercially feasible, assemble all or part of the Collateral as
directed by the Collateral Agent and make it available to the Collateral Agent at a place and time to be designated by the Collateral Agent that is reasonably convenient to both
parties; (ii) without notice except as specified below or as otherwise required pursuant to Section 9-611 of the UCC, sell the Collateral or any part thereof in one or more parcels at
public or private sale, at any of the Collateral Agent’s offices or elsewhere, for cash, on credit or for future delivery, and upon such other terms as are in accordance with applicable
law; (iii) occupy any premises owned or leased by any of the Grantors where the Collateral or any part thereof is assembled or located for a reasonable period in order to effectuate
its rights and remedies hereunder or under law; and (iv) exercise any and all rights and remedies of any of the Grantors under or in connection with the Collateral, or otherwise in
respect of the Collateral, including, without limitation, (A) any and all rights of Grantor to demand or otherwise require payment of any amount under, or performance of any
provision of, the Assigned Agreements, the Receivables, the Related Contracts and the other Collateral, (B) withdraw, or cause or direct the withdrawal, of all funds with respect to
the Account Collateral and (C) exercise all other rights and remedies with respect to the Assigned Agreements, the Receivables, the Related Contracts and the other Collateral,
including, without limitation, those set forth in Section 9-607 of the UCC. Grantor agrees that, to the extent notice of sale shall be required by law, at least ten (10) days’ notice to
Grantor of the time and place of any public sale or the time after which any private sale is to be made shall constitute reasonable notification. The Collateral Agent shall not be
obligated  to  make  any  sale  of  Collateral  regardless  of  notice  of  sale  having  been  given.  The  Collateral Agent  may  adjourn  any  public  or  private  sale  from  time  to  time  by
announcement at the time and place fixed therefor, and such sale may, without further notice (except as otherwise required by Section 9-611 of the UCC), be made at the time and
place to which it was so adjourned.

(b)         Any cash held by or on behalf of the Collateral Agent and all cash proceeds received by or on behalf of the Collateral Agent in respect of any
sale of, collection from, or other realization upon all or any part of the Collateral may, in the discretion of the Collateral Agent, be held by the Collateral Agent as collateral for the
benefit of the Secured Parties against, all or any part of the Secured Obligations. Any surplus of such cash or cash proceeds held by or on the behalf of the Collateral Agent and
remaining after payment in full of all the Secured Obligations shall be paid over to Grantor or to whomsoever may be lawfully entitled to receive such surplus.

(c)         All payments received by any Grantor under or in connection with any Assigned Agreement or otherwise in respect of the Collateral shall be
received in trust for the benefit of the Collateral Agent, shall be segregated from other funds of Grantor and shall be forthwith paid over to the Collateral Agent in the same form as
so received (with any necessary endorsement).

(d)        [RESERVED].

(e)         In the event of any sale or other disposition of any of the Intellectual Property Collateral of Grantor, the goodwill symbolized by any Trademarks
subject  to  such  sale  or  other  disposition  shall  be  included  therein,  and  Grantor  shall  supply  to  the  Collateral Agent  or  its  designee  Grantor’s  know-how  and  expertise,  and
documents and things relating to any Intellectual Property Collateral subject to such sale or other disposition, and Grantor’s customer lists and other records and documents
relating to such Intellectual Property Collateral and to the manufacture, distribution, advertising and sale of products and services of Grantor.

Exhibit C-17

 
  
 
 
 
 
 
 
 
 
that, upon request of the Collateral Agent, Grantor will, at its own expense:

(f)         If the Collateral Agent shall exercise its right to sell all or any of the Security Collateral of any Grantor pursuant to this Section 20, Grantor agrees

(i)          execute and deliver, and cause each issuer of such Security Collateral contemplated to be sold and the directors and officers thereof to
execute and deliver, all such instruments and documents, and do or cause to be done all such other acts and things, as may be necessary or, in the opinion of the Collateral Agent,
advisable to register such Security Collateral under the provisions of the Securities Act of 1933 (as amended from time to time, the “Securities Act”), to cause the registration
statement relating thereto to become effective and to remain effective for such period as prospectuses are required by law to be furnished and to make all amendments and
supplements thereto and to the related prospectus that, in the opinion of the Collateral Agent or the other Secured Parties, are necessary or advisable, all in conformity with the
requirements of the Securities Act and the rules and regulations of the Securities and Exchange Commission applicable thereto;

governmental approvals for the sale of such Security Collateral, as requested by the Collateral Agent;

(ii)                  use  its  best  efforts  to  qualify  the  Security  Collateral  under  the  state  securities  or  “Blue  Sky”  laws  and  to  obtain  all  necessary

statement that will satisfy the provisions of Section 11(a) of the Securities Act;

(iii)        cause each such issuer of such  Security  Collateral to make available to its security holders, as soon as practicable, an earnings

or the other Secured Parties, advisable to enable the Collateral Agent to effect the sale of such Security Collateral upon such terms as are in accordance with applicable law; and

(iv)        provide the Collateral Agent with such other information and projections as may be necessary or, in the opinion of the Collateral Agent

thereof valid and binding and in compliance with applicable law.

(v)         do or cause to be done all such other acts and things as may be necessary to make such sale of such Security Collateral or any part

(g)         The Collateral Agent is authorized, in connection with any sale of the Security Collateral pursuant to this Section 20, to deliver or otherwise
disclose to any prospective purchaser of the Security Collateral: (i) any registration statement or prospectus, and all supplements and amendments thereto, prepared pursuant to
subsection (f)(i) above; (ii) any information and projections provided to it pursuant to subsection (f)(iv) above; and (iii) any other information in its possession relating to such
Security Collateral.

(h)         Grantor acknowledges the impossibility of ascertaining the amount of damages that would be suffered by the Secured Parties by reason of the
failure by Grantor to perform any of the covenants contained in subsection (f) above and, consequently, agrees that, if Grantor shall fail to perform any of such covenants, it will
pay,  as  liquidated  damages  and  not  as  a  penalty,  an  amount  equal  to  the  value  of  the  Security  Collateral  on  the  date  the  Collateral Agent  shall  demand  compliance  with
subsection (f) above.

Exhibit C-18

 
  
 
 
 
 
 
 
 
 
 
 
Section 21.          Indemnity and Expenses.

(a)         Grantor agrees to indemnify, defend and save and hold harmless each Secured Party and each of their Affiliates and their Related Parties (each,
an “Indemnified Party”) from and against, and shall pay on demand, any and all claims, damages, losses, liabilities and expenses (including, without limitation, reasonable fees and
expenses of counsel) that may be incurred by or asserted or awarded against any  Indemnified  Party, in each case arising out of or in connection with or resulting from this
Agreement (including, without limitation, enforcement of this Agreement); provided that such indemnity shall not, as to any Indemnified Party, be available to the extent that such
losses, claims, damages, liabilities or related expenses (x) are determined by a court of competent jurisdiction by final and nonappealable judgment to have resulted from the bad
faith, gross negligence or willful misconduct of such Indemnified Party or any of its officers, directors or employees, or (y) arising from disputes solely among the Collateral Agent,
the  Buyers  and/or  their  transferees  (other  than  in  respect  of  disputes  against  an  Indemnitee  in  its  capacity  as  Collateral Agent  or  any  similar  role  under  the  Transaction
Documents).

(b)         Without limiting the foregoing clause (a), Grantor will upon demand pay to the Collateral Agent the amount of any and all (1) reasonable
expenses, including, without limitation, the reasonable fees and expenses of its counsel and of any experts and agents, that the Collateral Agent may incur in connection with
(i) the administration of this Agreement, and (ii) the custody, preservation, use or operation of, or the sale of, collection from or other realization upon, any of the Collateral of
Grantor, and (2) expenses, including, without limitation, the fees and expenses of its counsel and of any experts and agents, that the Collateral Agent may incur in connection with
(i) the exercise or enforcement of any of the rights of the Collateral Agent or the other Secured Parties hereunder or (ii) the failure by Grantor to perform or observe any of the
provisions hereof.

Section 22.         Amendments; Waivers; Additional Grantors; Etc. No amendment or waiver of any provision of this Agreement, and no consent to any departure
by any Grantor herefrom, shall in any event be effective unless the same shall be in writing and signed by the Collateral Agent, and then such waiver or consent shall be effective
only in the specific instance and for the specific purpose for which given. No failure on the part of the Collateral Agent to exercise, and no delay in exercising any right hereunder,
shall operate as a waiver thereof; nor shall any single or partial exercise of any such right preclude any other or further exercise thereof or the exercise of any other right.

Exhibit C-19

 
  
 
 
 
 
 
 
Section 

23.          Notices,  Etc.  Except  as  otherwise  provided  herein,  whenever  it  is  provided  herein  that  any  notice,  demand,  request,  consent,  approval,
declaration or other communication shall or may be given to or served upon any of the parties by any other party, or whenever any of the parties desires to give and serve upon
any other party any communication with respect to this Agreement, each such notice, demand, request, consent, approval, declaration or other communication shall be in writing
and shall be given in the manner and to the address, and deemed received, as provided for in accordance with the terms of the Collateral Agency Agreement. Delivery by email or
facsimile of an executed counterpart of any amendment, supplement or waiver of any provision of this Agreement or any Schedule or Exhibit relating thereto shall be effective as
delivery of an original executed counterpart thereof.

Section  24.          Continuing Security Interest. This Agreement shall create a continuing security interest in the Collateral and shall (a) remain in full force and
effect until the indefeasible payment in full in cash of the Secured Obligations, (b) be binding upon Grantor, its successors and assigns and (c) inure, together with the rights and
remedies of the Collateral Agent hereunder, to the benefit of the Secured Parties and their respective successors, transferees and assigns.

Section 25.          Release; Termination.

(a)         Upon any sale, lease, transfer or other disposition of any item of Collateral of Grantor (other than sales of Inventory in the ordinary course of
business) in accordance with the terms of the Transaction Documents, the Collateral Agent will, at Grantor’s expense, execute and deliver to Grantor such documents as Grantor
shall reasonably request to evidence the release of such item(s) of Collateral from the assignment and security interest granted hereby; provided, however, that (i) at the time of
such request and such release no Event of Default shall have occurred and be continuing, (ii) Grantor shall have delivered to the Collateral Agent, at least ten (10) Business Days
prior to the date of the proposed release, a written request for release describing the item of Collateral and the terms of the sale, lease, transfer or other disposition in reasonable
detail,  including,  without  limitation,  the  price  thereof  and  any  expenses  in  connection  therewith,  together  with  a  form  of  release  for  execution  by  the  Collateral Agent  and  a
certificate of Grantor to the effect that the transaction is in compliance with the Transaction Documents and as to such other matters as the Collateral Agent may request, (iii) the
proceeds of any such sale, lease, transfer or other disposition required to be applied, or any payment to be made in connection therewith, shall, to the extent so required, be paid or
made to, or in accordance with the instructions of, the Collateral Agent, and (iv) the Collateral Agent shall have received written direction from the Buyers in accordance with the
Collateral Agency Agreement.

(b)         Upon the indefeasible payment in full in cash of the Secured Obligations, other than any unasserted contingent Obligations, the pledge and
security interest granted hereby shall terminate and all rights to the Collateral shall revert to Grantor. Upon any such termination, the Secured Parties will, at the Grantor’s expense,
execute and deliver to Grantor such documents as Grantor shall reasonably request to evidence such termination.

Section  26.         Execution in Counterparts. This Agreement may be executed in any number of counterparts, each of which when so executed shall be deemed to
be an original and all of which taken together shall constitute one and the same agreement. Delivery of an executed counterpart of a signature page to this Agreement by email or
facsimile shall be effective as delivery of an original executed counterpart of this Agreement.

Exhibit C-20

 
  
 
 
 
 
 
 
 
 
Section 27.          Governing Law; Jurisdiction; Waiver of Jury Trial, Etc. 

( a )         GOVERNING LAW. THIS AGREEMENT AND ANY CLAIMS, CONTROVERSY, DISPUTE OR CAUSE OF ACTION (WHETHER IN TORT OR
OTHERWISE) BASED ON, ARISING OUT OF OR RELATING TO THIS GUARANTY AND THE TRANSACTIONS CONTEMPLATED HEREBY SHALL BE GOVERNED BY, AND
CONSTRUED IN ACCORDANCE WITH, THE LAW OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS (OTHER THAN SECTIONS 5-1401 AND 5-
1402 OF THE NEW YORK GENERAL OBLIGATIONS LAWS).

(b)         SUBMISSION TO JURISDICTION. GRANTOR IRREVOCABLY AND UNCONDITIONALLY SUBMITS, FOR ITSELF AND ITS PROPERTY, TO
THE  NONEXCLUSIVE  JURISDICTION  OF  THE  COURTS  OF  THE  STATE  OF  NEW  YORK  SITTING  IN  NEW  YORK  COUNTY  OR  OF  THE  UNITED  STATES  FOR  THE
SOUTHERN DISTRICT OF SUCH STATE, AND ANY APPELLATE COURT FROM ANY THEREOF, IN ANY ACTION OR PROCEEDING ARISING OUT OF OR RELATING TO
THIS AGREEMENT, OR FOR RECOGNITION OR ENFORCEMENT OF ANY JUDGMENT, AND EACH OF THE PARTIES HERETO IRREVOCABLY AND UNCONDITIONALLY
AGREES THAT ALL CLAIMS IN RESPECT OF ANY SUCH ACTION OR PROCEEDING MAY BE HEARD AND DETERMINED IN SUCH NEW YORK COURT OR, TO THE
FULLEST EXTENT PERMITTED BY APPLICABLE LAW, IN SUCH FEDERAL COURT. EACH OF THE PARTIES HERETO AGREES THAT A FINAL JUDGMENT IN ANY SUCH
ACTION OR PROCEEDING SHALL BE CONCLUSIVE AND MAY BE ENFORCED IN OTHER JURISDICTIONS BY SUIT ON THE JUDGMENT OR IN ANY OTHER MANNER
PROVIDED  BY  LAW.  NOTHING  IN  THIS  AGREEMENT  SHALL  AFFECT  ANY  RIGHT  THAT  THE  COLLATERAL  AGENT  OR  ANY  OTHER  SECURED  PARTY  MAY
OTHERWISE HAVE TO BRING ANY ACTION OR PROCEEDING RELATING TO THIS AGREEMENT AGAINST ANY GRANTOR OR ITS PROPERTIES IN THE COURTS OF
ANY JURISDICTION.

( c )         WAIVER  OF  VENUE.  GRANTOR  IRREVOCABLY AND  UNCONDITIONALLY  WAIVES,  TO  THE  FULLEST  EXTENT  PERMITTED  BY
APPLICABLE LAW, ANY OBJECTION THAT IT MAY NOW OR HEREAFTER HAVE TO THE LAYING OF VENUE OF ANY ACTION OR PROCEEDING ARISING OUT OF OR
RELATING TO THIS AGREEMENT IN ANY COURT REFERRED TO IN PARAGRAPH (b) OF THIS SECTION. GRANTOR HEREBY IRREVOCABLY WAIVES, TO THE FULLEST
EXTENT PERMITTED BY APPLICABLE LAW, THE DEFENSE OF AN INCONVENIENT FORUM TO THE MAINTENANCE OF SUCH ACTION OR PROCEEDING IN ANY SUCH
COURT.

NOTICES IN SECTION 23.

( d )         SERVICE OF PROCESS. GUARANTOR HERETO IRREVOCABLY CONSENTS TO SERVICE OF PROCESS IN THE MANNER PROVIDED FOR

Exhibit C-21

 
  
 
 
 
 
 
 
 
( e )         WAIVER  OF  JURY  TRIAL.  GUARANTOR  HERETO  HEREBY  IRREVOCABLY  WAIVES,  TO  THE  FULLEST  EXTENT  PERMITTED  BY

APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN ANY LEGAL PROCEEDING DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THIS
AGREEMENT  OR  THE  TRANSACTIONS  CONTEMPLATED  HEREBY  (WHETHER  BASED  ON  CONTRACT,  TORT  OR  ANY  OTHER  THEORY).  EACH  PARTY  HERETO
(A) CERTIFIES THAT NO REPRESENTATIVE, AGENT OR ATTORNEY OF ANY OTHER PERSON HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER
PERSON WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE FOREGOING WAIVER AND (B) ACKNOWLEDGES THAT IT AND THE OTHER PARTIES
HERETO HAVE BEEN INDUCED TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS IN THIS SECTION.

SIGNATURE PAGE FOLLOWS

Exhibit C-22

 
 
 
 
 
 
written.

IN WITNESS WHEREOF, Grantor has caused this Agreement to be duly executed and delivered by its officer thereunto duly authorized as of the date first above

APPLIED DNA SCIENCES, INC.,
a Delaware corporation

By:
Name:   Beth Jantzen, CPA
Title:     Chief Financial Officer

SIGNATURES CONTINUE ON NEXT PAGE

Signature Page to Security Agreement

 
 
 
 
 
 
 
 
        
 
 
 
 
 
 
ACCEPTED AND AGREED
as of the date first written above by:

DELAWARE TRUST COMPANY,
as Collateral Agent

By:
Name:  
Title:

Signature Page to Security Agreement

 
 
 
 
 
 
 
 
 
 
 
 
          
 
 
 
 
 
 
Exhibit A to the
Security Agreement

FORM OF INTELLECTUAL PROPERTY SECURITY AGREEMENT

This INTELLECTUAL PROPERTY SECURITY AGREEMENT (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “IP Security Agreement”) dated __________, 2018 is made by APPLIED DNA SCIENCES, INC. a Delaware corporation (the “Grantor”), in favor of DELAWARE TRUST
COMPANY, a Delaware corporation, as collateral agent (the “Collateral Agent”) for the Secured Parties (as defined in the Security Agreement referred to below).

otherwise modified from time to time, the “Securities Purchase Agreement”) with the Buyers party thereto.

WHEREAS, Grantor is party to the Securities Purchase Agreement dated as of August 31, 2018 (as amended, restated, amended and restated, supplemented or

WHEREAS, pursuant to the Securities Purchase Agreement, the Grantor has executed and delivered that certain Security Agreement dated as of the date hereof
made by the Grantor to the Collateral Agent for the benefit of the Secured Parties (as amended, restated, amended and restated, supplemented or otherwise modified from time to
time, the “Security Agreement”; the capitalized terms defined therein and not otherwise defined herein being used herein as therein defined).

WHEREAS, under the terms of the Security Agreement, the Grantor has granted to the Collateral Agent, for the ratable benefit of the Secured Parties, a security
interest in, among other property, certain intellectual property of the Grantor, and have agreed as a condition thereof to execute this IP Security Agreement for recording with the
U.S. Patent and Trademark Office, the United States Copyright Office and other governmental authorities.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Grantor agrees as follows:

right, title and interest in and to the following (the “Collateral”):

SECTION 1. Grant of Security. Grantor hereby grants to the Collateral Agent for the ratable benefit of the Secured Parties a security interest in all of Grantor’s

thereto, including, without limitation, those set forth in Schedule A hereto (the “Patents”);

(i)          all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all improvements

(ii)         all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and other source
identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent that, and solely
during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under applicable federal
law), together, in each case, with the goodwill symbolized thereby, including, without limitation, those set forth in Schedule B hereto (the “Trademarks”);

 
 
 
 
 
 
 
 
 
 
 
 
 
(iii)        all copyrights, including, without limitation, copyrights in Computer Software (as hereinafter defined), internet web sites and the content thereof, whether
registered  or  unregistered,  including,  without  limitation,  the  copyright  registrations  and  applications  and  exclusive  copyright  licenses  set  forth  in Schedule  C  hereto  (the
“Copyrights”);

(iv)        all reissues, divisions, continuations, continuations-in-part, extensions, renewals and reexaminations of any of the foregoing, all rights in the foregoing
provided by international treaties or conventions, all rights corresponding thereto throughout the world and all other rights of any kind whatsoever of Grantor accruing thereunder
or pertaining thereto;

respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages; and

(v)         any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation, misuse or breach with

Obligations (as defined in the Security Agreement) relating to, any and all of the Collateral of or arising from any of the foregoing.

(vi)                any  and  all  proceeds  of,  collateral  for,  income,  royalties  and  other  payments  now  or  hereafter  due  and  payable  with  respect  to,  and  supporting

SECTION  2.          Security for Obligations. The grant of a security interest in the Collateral by Grantor under this IP Security Agreement secures the payment of
all Secured Obligations now or hereafter existing under or in respect of the Transaction Documents, whether direct or indirect, absolute or contingent, and whether for principal,
reimbursement obligations, interest, premiums, penalties, fees, indemnifications, contract causes of action, costs, expenses or otherwise. Without limiting the generality of the
foregoing, this IP Security Agreement secures, as to Grantor, the payment of all amounts that constitute part of the Secured Obligations and that would be owed by Grantor to any
Secured  Party  under  the  Transaction  Documents  but  for  the  fact  that  such  Secured  Obligations  are  unenforceable  or  not  allowable  due  to  the  existence  of  a  bankruptcy,
reorganization or similar proceeding involving Grantor.

Trademarks and any other applicable government officer record this IP Security Agreement.

SECTION 

3.         Recordation.  Grantor  authorizes  and  requests  that  the  Register  of  Copyrights,  the  Commissioner  for  Patents  and  the  Commissioner  for

be deemed to be an original and all of which taken together shall constitute one and the same agreement.

SECTION  4.          Execution in Counterparts. This IP Security Agreement may be executed in any number of counterparts, each of which when so executed shall

SECTION  5.         Grants, Rights and Remedies. This IP Security Agreement has been entered into in conjunction with the provisions of the Security Agreement.
Grantor does hereby acknowledge and confirm that the grant of the security interest hereunder to, and the rights and remedies of, the Collateral Agent with respect to the Collateral
are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated herein by reference as if fully set forth herein.

-2-

 
  
 
 
 
 
 
 
 
 
 
 
LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS.

SECTION  6.          GOVERNING LAW. THIS IP SECURITY AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE

[remainder of page intentionally blank]

-3-

 
 
 
 
 
 
first above written.

IN WITNESS WHEREOF, Grantor has caused this IP Security Agreement to be duly executed and delivered by its officer thereunto duly authorized as of the date

APPLIED DNA SCIENCES, INC.

By
Name:
Title:

Address for Notices:

 
 
 
 
 
 
 
        
 
 
 
 
 
 
 
 
 
 
 
 
 
Exhibit B to the
Security Agreement

FORM OF INTELLECTUAL PROPERTY SECURITY AGREEMENT SUPPLEMENT

This INTELLECTUAL PROPERTY SECURITY AGREEMENT SUPPLEMENT (as amended, restated, amended and restated, supplemented or otherwise modified
from time to time, the “IP Security Agreement Supplement”) dated __________, 20__, is made by APPLIED DNA SCIENCES, INC. a Delaware corporation (the “Grantors”) in favor
of DELAWARE TRUST COMPANY, a Delaware corporation, as collateral agent (the “ Collateral Agent”) for the Secured Parties (as defined in the Security Agreement referred to
below).

otherwise modified from time to time, the “Securities Purchase Agreement”) with the Buyers party thereto.

WHEREAS, Grantor is party to the Securities Purchase Agreement dated as of [August 31], 2018 (as amended, restated, amended and restated, supplemented or

WHEREAS, pursuant to the Securities Purchase Agreement, the Grantor has executed and delivered that certain Security Agreement dated as of __________,
2018 made by the Grantor to the Collateral Agent for the benefit of the Secured Parties (as amended, restated, amended and restated, supplemented or otherwise modified from time
to time, the “Security Agreement”) and that certain Intellectual Property Security Agreement dated [insert date of Intellectual Property Security Agreement] made by the Grantor
to the Collateral Agent for the benefit of the Secured Parties (as amended, restated, amended and restated, supplemented or otherwise modified from time to time, the “IP Security
Agreement”; the capitalized terms defined therein and not otherwise defined herein being used herein as therein defined).

WHEREAS, under the terms of the Security Agreement, the Grantor has granted to the Collateral Agent, for the ratable benefit of the Secured Parties, a security
interest in the Additional Collateral (as defined in Section 1 below) of the Grantor and has agreed as a condition thereof to execute this IP Security Agreement Supplement for
recording with the U.S. Patent and Trademark Office, the United States Copyright Office and other governmental authorities.

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Grantor agrees as follows:

such Grantor’s right, title and interest in and to the following (the “Additional Collateral”):

SECTION  1.          Grant of Security. Each Grantor hereby grants to the Collateral Agent, for the ratable benefit of the Secured Parties, a security interest in all of

thereto, including, without limitation, those set forth in Schedule A hereto (the “Patents”);

(i)          all patents, patent applications, utility models and statutory invention registrations, all inventions claimed or disclosed therein and all improvements

 
 
 
 
 
 
 
 
 
 
 
 
(ii)         all trademarks, service marks, domain names, trade dress, logos, designs, slogans, trade names, business names, corporate names and other source
identifiers, whether registered or unregistered (provided that no security interest shall be granted in United States intent-to-use trademark applications to the extent that, and solely
during the period in which, the grant of a security interest therein would impair the validity or enforceability of such intent-to-use trademark applications under applicable federal
law), together, in each case, with the goodwill symbolized thereby, including, without limitation, those set forth in Schedule B hereto (the “Trademarks”);

(ii)         all copyrights, including, without limitation, copyrights in Computer Software (as hereinafter defined), internet web sites and the content thereof, whether
registered  or  unregistered,  including,  without  limitation,  the  copyright  registrations  and  applications  and  exclusive  copyright  licenses  set  forth  in Schedule  C  hereto  (the
“Copyrights”);

(iii)        all reissues, divisions, continuations, continuations-in-part, extensions, renewals and reexaminations of any of the foregoing, all rights in the foregoing
provided by international treaties or conventions, all rights corresponding thereto throughout the world and all other rights of any kind whatsoever of such Grantor accruing
thereunder or pertaining thereto;

(iv)        all any and all claims for damages and injunctive relief for past, present and future infringement, dilution, misappropriation, violation, misuse or breach

with respect to any of the foregoing, with the right, but not the obligation, to sue for and collect, or otherwise recover, such damages; and

Obligations (as defined in the Security Agreement) relating to, any and all of the foregoing or arising from any of the foregoing.

(v)                  any  and  all  proceeds  of,  collateral  for,  income,  royalties  and  other  payments  now  or  hereafter  due  and  payable  with  respect  to,  and  supporting

2.          Security for Obligations.  The  grant  of  a  security  interest  in  the Additional  Collateral  by  the  Grantor  under  this  IP  Security Agreement
Supplement secures the payment of all Secured Obligations now or hereafter existing under or in respect of the Loan Documents, whether direct or indirect, absolute or contingent,
and whether for principal, reimbursement Obligations, interest, premiums, penalties, fees, indemnifications, contract causes of action, costs, expenses or otherwise.

SECTION 

Trademarks and any other applicable government officer to record this IP Security Agreement Supplement.

SECTION  3.          Recordation. The Grantor authorizes and requests that the Register of Copyrights, the Commissioner for Patents and the Commissioner for

SECTION  4.          Grants, Rights and Remedies. This IP Security Agreement Supplement has been entered into in conjunction with the provisions of the Security
Agreement. The Grantor does hereby acknowledge and confirm that the grant of the security interest hereunder to, and the rights and remedies of, the Collateral Agent with
respect to the Additional Collateral are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated herein by reference as if fully set forth
herein.

SECTION 5.          GOVERNING LAW. THIS IP SECURITY AGREEMENT SUPPLEMENT SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE

WITH, THE LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO CONFLICTS OF LAWS.

-2-

 
 
 
 
 
 
 
 
 
 
 
 
 
authorized as of the date first above written.

IN  WITNESS  WHEREOF,  the  Grantor  has  caused  this  IP  Security Agreement  Supplement  to  be  duly  executed  and  delivered  by  its  officer  thereunto  duly

By  

Name:
Title:

Address for Notices:

-3-

 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
Part I: None.

Part II: None.

SCHEDULE I

Investment Property

 
 
 
 
 
 
 
·

·

Bank of America, Operating Account, Account #004831291068

Bank of America, Money Market Account, Account #483043680826

SCHEDULE II

Deposit Accounts

 
 
 
 
 
 
 
None.

SCHEDULE III

Assigned Agreements

 
 
 
 
 
 
SCHEDULE IV

Intellectual Property

COPYRIGHTS: None.

TRADEMARKS:

Docket No.
2542-83
2542-82
2542-47
2542-75
2542-95
2542-89
2542-84
2542-89A

PATENTS:

Client Ref 
No.

8251-61
2542-75

Country
United States
United States
United States
United States
United States
United States
United States
United States

 Application 
Date
12/13/2016
12/20/2016
06/09/2008
12/09/2016
5/16/2017
3/6/2017
12/23/2016
8/16/2017

Application
No.
87/267,216
87/275,103
77/494,134
87/263,954
87/451,220
87/360,183
87/279,792
87/571,726

 Registration
Date

 Registration No.

12/12/2017
01/05/2010
05/23/2017

10/17/2017
08/22/2017

5,356,414
3,735,415
5,209,527

5,313,762
5,269,735

Status
Filed
Registered
Registered
Registered
Filed
Registered
Registered
Filed

Country
United States

Status
Granted

Application
No.
12/384,554

Application
Date
04/06/2009

Title
  METHOD FOR A CONTINUOUS RAPID THERMAL
CYCLE SYSTEM

Patent No.
8,163,489

Grant Date
04/24/2012

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
None.

SCHEDULE V

Commercial Tort Claims

 
 
 
 
 
 
SCHEDULE VI

Location of Chief Executive Office, Type of Organization, Jurisdiction of Organization and 
Organizational Identification Number

·

·

·

Location of Chief Executive Office: 50 Health Sciences Drive, Stony Brook, NY 11790

Type of Organization: Corporation

Jurisdiction of Organization: Delaware

· Organization Identification Number: 59-2262718

 
 
 
 
 
 
 
 
 
None.

SCHEDULE VII

Changes in Name, Location, Etc.

 
 
 
 
 
 
·

50 Health Sciences Drive, Stony Brook, NY 11790

SCHEDULE VIII

Locations of Equipment, Inventory and Books and Records

 
 
 
 
 
 
None.

SCHEDULE IX

Letters of Credit

 
 
 
 
 
 
None.

SCHEDULE X

Permitted Liens

 
 
 
 
 
 
SCHEDULE XI

Excluded Assets

·

·

·

the Equity Interests in Applied DNA Sciences India Private Limited, a corporation formed under the laws of India, owned by the Grantor;

the Equity Interests in APDN (B.V.I.) Inc., a corporation formed under the laws of the British Virgin Islands, owned by the Grantor; and

all Excluded Accounts.

 
 
 
 
 
 
 
 
Exhibit D

TRANSFER AGENT INSTRUCTIONS
APPLIED DNA SCIENCES, INC.

August 31, 2018

American Stock Transfer and Trust Company, LLC
Operations Center
6201 15th Avenue, Third Floor
Brooklyn, NY 11219
Attention: [●]

Ladies and Gentlemen:

Reference is made to that certain Securities Purchase Agreement, dated as of August 31, 2018 (the “Agreement”), by and among Applied DNA Sciences, Inc., a Delaware

corporation (the “Company”), and the investors listed on the Schedule of Buyers attached thereto (collectively, the “Buyers”), pursuant to which the Company is issuing to the
Buyers secured convertible notes of the Company (the “Notes”), which will be convertible into shares of the Company’s common stock, $0.001 par value per share (the “Common
Stock”). The shares of Common Stock to be converted thereunder are referred to herein as the “Conversion Shares.”

This letter shall serve as our authorization and direction to you (provided that you are the transfer agent of the Company at such time) to issue the Conversion Shares to
or upon the order of a Buyer from time to time upon delivery to you of a properly completed and duly executed Conversion Notice, in the form attached hereto as Exhibit I, which
has been acknowledged by the Company as indicated by the signature of a duly authorized officer of the Company thereon.

Specifically, upon receipt by the Company of a copy of a Conversion Notice, the Company shall as soon as practicable, but in no event later than two (2) Business Days

(as defined below) after receipt of such Conversion Notice, deliver a Conversion Notice, which shall constitute an irrevocable instruction to you to process such Conversion
Notice in accordance with the terms of these instructions. Upon your receipt of a copy of the executed Conversion Notice, you shall use your best efforts to, (A) provided you are
participating in the DTC Fast Automated Securities Transfer Program, credit the aggregate number of shares of Common Stock to which Buyer shall be entitled to Buyer’s or its
designee’s balance account with DTC through its Deposit/Withdrawal at Custodian system or (B) issue and deliver (via reputable overnight courier) to Buyer, a certificate
representing such Securities that is free from all restrictive and other legends, registered in the name of Buyer or its designee (the date by which such credit is so required to be
made to the balance account of Buyer’s or Buyer’s nominee with DTC or such certificate is required to be delivered to Buyer pursuant to the foregoing is referred to herein as the
“Required Delivery Date”).

You acknowledge and agree that so long as you have previously received (a) written confirmation from the outside legal counsel of the Company that either (i) a
registration statement covering resales of the Conversion Shares has been declared effective by the Securities and Exchange Commission (the “SEC”) under the Securities Act of
1933, as amended (the “1933 Act”), or (ii) that sales of the Conversion Shares may be made in conformity with Rule 144 under the 1933 Act, and (b) if applicable, a copy of such
registration statement, then, as soon as practicable after your receipt of a notice of transfer or Conversion Notice, you shall issue the certificates representing the Conversion
Shares and such certificates shall not bear any legend restricting transfer of the Conversion Shares thereby and should not be subject to any stop-transfer restriction; provided,
however, that if such Conversion Shares are not registered for resale under the 1933 Act or able to be sold under Rule 144, then the certificates for such Conversion Shares shall
bear the following legend:

Exhibit D-1

 
  
 
 
 
 
 
 
 
 
 
 
 
THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR
APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED (I) IN THE
ABSENCE OF (A) AN EFFECTIVE REGISTRATION STATEMENT FOR THE SECURITIES UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR (B) AN
OPINION OF COUNSEL TO THE HOLDER (IF REQUESTED BY THE COMPANY), IN A FORM REASONABLY ACCEPTABLE TO THE COMPANY, THAT
REGISTRATION IS NOT REQUIRED UNDER SAID ACT OR (II) UNLESS SOLD OR ELIGIBLE TO BE SOLD PURSUANT TO RULE 144 OR RULE 144A UNDER
SAID ACT. NOTWITHSTANDING THE FOREGOING, THE SECURITIES MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR
OTHER LOAN OR FINANCING ARRANGEMENT SECURED BY THE SECURITIES.

A form of written confirmation from the Company’s outside legal counsel that a registration statement covering resales of the Conversion Shares has been declared

effective by the SEC under the 1933 Act is attached hereto as Exhibit II.

Please execute this letter in the space indicated to acknowledge your agreement to act in accordance with these instructions. Should you have any questions concerning

this matter, please contact me at (631) 240-8800.

Very truly yours,

APPLIED DNA SCIENCES, INC.

By:

Name: Beth Jantzen
Title: Chief Financial Officer

Exhibit D-2

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
THE FOREGOING INSTRUCTIONS ARE
ACKNOWLEDGED AND AGREED TO
this 31st day of August, 2018
AMERICAN STOCK TRANSFER AND TRUST COMPANY, LLC

By:

Name:
Title:

Enclosures

Exhibit D-3

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
EXHIBIT I

APPLIED DNA SCIENCES, INC.
CONVERSION NOTICE

Reference is made to the Secured Convertible Note (the “Note”) issued to the undersigned by Applied DNA Sciences, Inc. (the “Company”). In accordance with and

pursuant to the Note, the undersigned hereby elects to convert the Conversion Amount (as defined in the Note) of the Note indicated below into Conversion Shares (as defined in
the Note) of the Company, as of the date specified below.

Date of Conversion:

Aggregate Conversion Amount to be converted:

Please confirm the following information:

Conversion Price:

Number of shares of Common Stock to be issued:

Please issue the Common Stock into which the Conversion Amount of the Note is being converted in the following name and to the following address:

Issue to:

Facsimile Number:

Authorization:

By:

Title:

Dated:

Account Number:
(if electronic book entry transfer)

Transaction Code Number:
(if electronic book entry transfer)

Exhibit I-1

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
The Company hereby acknowledges this Conversion Notice and hereby directs American Stock Transfer and Trust Company, LLC to issue the above indicated number of

shares of Common Stock in accordance with the Transfer Agent Instructions dated August 31, 2018 from the Company and acknowledged and agreed to by American Stock
Transfer and Trust Company, LLC.

ACKNOWLEDGMENT

APPLIED DNA SCIENCES, INC

By:

Name:
Title:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
EXHIBIT II

FORM OF NOTICE OF EFFECTIVENESS
OF REGISTRATION STATEMENT

American Stock Transfer and Trust Company, LLC
Operations Center
6201 15th Avenue, Third Floor
Brooklyn, NY 11219
Telephone: (718) 921-8210
Attention: [●]

Re: Applied DNA Sciences, Inc.

Ladies and Gentlemen:

We are counsel to Applied DNA Sciences, Inc., a Delaware corporation (the “Company”), and have represented the Company in connection with that certain Securities Purchase
Agreement, dated as of [●], 2018 (the “Securities Purchase Agreement”), entered into by and among the Company and the buyers named therein (collectively, the “Holders”)
pursuant to which the Company issued to the Holders secured convertible notes (the “Notes”) which are convertible into the Company’s common stock, $0.001 par value per share
(the “Common Stock”). Pursuant to the Securities Purchase Agreement, the Company also has entered into a Registration Rights Agreement with the Holders (the “Registration
Rights Agreement”) pursuant to which the Company agreed, among other things, to register the resale of the Registrable Securities (as defined in the Registration Rights
Agreement), including the shares of Common Stock issuable upon conversion of the Notes under the Securities Act of 1933, as amended (the “1933 Act”). In connection with the
Company’s obligations under the Registration Rights Agreement, on _______, 201_, the Company filed a Registration Statement on Form S-1 (File No. 333-_____________) (the
“Registration Statement”) with the Securities and Exchange Commission (the “SEC”) relating to the Registrable Securities which names each of the Holders as a selling
shareholder thereunder.

In connection with the foregoing, we advise you that the SEC has entered an order declaring the Registration Statement effective under the 1933 Act at [ENTER TIME OF
EFFECTIVENESS] on [ENTER DATE OF EFFECTIVENESS] and we have no knowledge, based upon our review of the list of current stop orders available on the SEC’s website,
that any stop order suspending its effectiveness has been issued or that any proceedings for that purpose are pending before, or threatened by, the SEC and the Registrable
Securities are available for resale under the 1933 Act pursuant to the Registration Statement.

Exhibit II-1

 
 
 
 
 
 
 
 
 
 
 
This letter shall serve as our standing instruction to you that the shares of Common Stock are freely transferable by the Holders pursuant to the Registration Statement. You need
not require further letters from us to effect any future legend-free issuance or reissuance of shares of Common Stock to the Holders as contemplated by the Company’s Irrevocable
Transfer Agent Instructions dated August 31, 2018, provided at the time of such reissuance, the Company has not otherwise notified you that the Registration Statement is
unavailable for the resale of the Registrable Securities.

cc: [LIST NAMES OF BUYERS]

Very truly yours,

[ISSUER’S COUNSEL]

By:

Exhibit II-2

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM’S CONSENT

We consent to the incorporation by reference in the Registration Statements of Applied DNA Sciences, Inc. on Form S-3 (File No. 333-202432, File No. 333-220481, File No. 333-
218158, File No. 333-214920 and File No. 333-208162) and Form S-8 (File No. 333-182350 and 333-205123) of our report dated December 18, 2018 which included an explanatory
paragraph as to the Company’s ability to continue as a going concern, with respect to our audits of the consolidated financial statements of Applied DNA Sciences, Inc. as of
September 30, 2018 and 2017, and for the years then ended, which report is included in this Annual Report on Form 10-K of Applied DNA Sciences, Inc. for the year ended
September 30, 2018.

Exhibit 23.1

/s/ Marcum llp

Marcum llp
Melville, NY
December 18, 2018

 
 
 
 
 
 
 
 
Exhibit 31.1

I, James A. Hayward, certify that:

CERTIFICATION

1.

2.

3.

4.

I have reviewed this Annual Report on Form 10-K of Applied DNA Sciences, Inc.;

Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light
of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition,
results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules
13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a)

(b)

(c)

(d)

Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that
material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the
period in which this report is being prepared;

Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide
reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally
accepted accounting principles;

Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the
disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the
registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal
control over financing reporting; and

5.

The  registrant’s  other  certifying  officer(s)  and  I  have  disclosed,  based  on  our  most  recent  evaluation  of  internal  control  over  financial  reporting,  to  the  registrant’s
auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a)

(b)

All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely
affect the registrant’s ability to record, process, summarize and report financial information; and

Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial
reporting.

Date:

December 18, 2018

/s/ James A. Hayward
James A. Hayward
President, Chief Executive Officer and Chairman
(Principal Executive Officer)

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Exhibit 31.2

I, Beth Jantzen, certify that:

CERTIFICATION

1.

2.

3.

4.

I have reviewed this Annual Report on Form 10-K of Applied DNA Sciences, Inc.;

Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light
of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition,
results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules
13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a)

(b)

(c)

(d)

Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that
material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the
period in which this report is being prepared;

Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide
reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally
accepted accounting principles;

Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the
disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the
registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal
control over financing reporting; and

5.

The  registrant’s  other  certifying  officer(s)  and  I  have  disclosed,  based  on  our  most  recent  evaluation  of  internal  control  over  financial  reporting,  to  the  registrant’s
auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a)

(b)

All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely
affect the registrant’s ability to record, process, summarize and report financial information; and

Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial
reporting.

Date:

December 18, 2018

/s/ Beth Jantzen
Beth Jantzen, CPA
Chief Financial Officer
(Principal Financial Officer)

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CERTIFICATION PURSUANT TO
18 U.S.C. §1350,
AS ADOPTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

Exhibit 32.1

In connection with the Annual Report on Form 10-K of Applied DNA Sciences, Inc. (the “Company”) for the fiscal year ended September 30, 2018, as filed with the
Securities and Exchange Commission on the date hereof (the “Report”), I, James A. Hayward, President, Chief Executive Officer and Chairman of the Company, certify, pursuant to
18 U.S.C. §1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1)

(2)

The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

/s/ James A. Hayward
James A. Hayward
President, Chief Executive Officer and Chairman
(Principal Executive Officer)

Date: December 18, 2018

* A signed original of this written statement required by Section 906 has been provided to Applied DNA Sciences, Inc. and will be retained by Applied DNA Sciences, Inc. and

furnished to the Securities and Exchange Commission or its staff upon request.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
CERTIFICATION PURSUANT TO
18 U.S.C. §1350,
AS ADOPTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

Exhibit 32.2

In connection with the Annual Report on Form 10-K of Applied DNA Sciences, Inc. (the “Company”) for the fiscal year ended September 30, 2018, as filed with the

Securities and Exchange Commission on the date hereof (the “Report”), I, Beth Jantzen, Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. §1350, as adopted
pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1)

(2)

The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

/s/ Beth Jantzen
Beth Jantzen, CPA
Chief Financial Officer
(Principal Financial Officer)

Date: December 18, 2018

* A signed original of this written statement required by Section 906 has been provided to Applied DNA Sciences, Inc. and will be retained by Applied DNA Sciences, Inc. and

furnished to the Securities and Exchange Commission or its staff upon request.