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Apricus Biosciences Inc.

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FY2008 Annual Report · Apricus Biosciences Inc.
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION 
WASHINGTON, DC  20549 

FORM 10-K 

(Mark One) 
[X] 

ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934  

For the fiscal year ended December 31, 2008 

OR 

[   ] 

TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 
1934 

For the transition period from           to            

Commission file number 0-22245 

NEXMED, INC. 
(Exact Name of Registrant as Specified in Its Charter) 

Nevada 

(State or Other Jurisdiction of Incorporation or 
Organization) 

87-0449967 

(I.R.S. Employer 
Identification No.) 

89 Twin Rivers Drive, East Windsor, NJ 08520 
(Address of Principal Executive Offices)   (Zip Code) 

(609) 371-8123 
(Registrant’s telephone number, including area code) 

Securities registered pursuant to Section 12(b) of the Act: 

Title of Each Class 

Name of Exchange on Which Registered 

Common Stock, par value $.001 

The NASDAQ Capital Market 

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities 

Act.  Yes __  No X   

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the 

Act.  Yes __  No X   

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of 
the  Securities  Exchange  Act  of  1934  during  the  preceding  12  months  (or  for  such  shorter  period  that  the  registrant  was 
Yes X   No___ 
required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. 

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained 
herein,  and  will  not  be  contained,  to  the  best  of  registrant’s  knowledge,  in  definitive  proxy  or  information  statements 
incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K.  ___  

Indicate  by  check  mark  whether  the  registrant  is  a  large  accelerated  filer,  an  accelerated  filer,  a  non-accelerated 
filer, or a smaller reporting company.  See definitions of “large accelerated filer”, “accelerated filer” and “smaller reporting 
company” in Rule 12b-2 of the Exchange Act (check one):  Large accelerated filer __  Accelerated filer  X   Non-accelerated 
filer _ __(do not check if a smaller reporting company)  Smaller reporting company  ___ 

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act).  Yes __  No 

X   

As of March 10, 2009, 84,410,736 shares of the common stock, par value $.001, of the registrant were outstanding.  
The  aggregate  market  value  of  the  common  stock  held  by  non-affiliates,  based  upon  the  last  sale  price  of  the  registrant’s 
common stock on June 30, 2008, was approximately $109 million. 

 
 
 
 
NEXMED, INC. 

INDEX TO ANNUAL REPORT ON FORM 10-K FILED WITH 
THE SECURITIES AND EXCHANGE COMMISSION 
YEAR ENDED DECEMBER 31, 2008 

ITEMS IN FORM 10-K 

PART I. 

Item 1. 

  BUSINESS. ...................................................................................................................................... 3 

Item 1A. 

RISK FACTORS .............................................................................................................................. 8 

Item 1B. 

UNRESOLVED STAFF COMMENTS ........................................................................................... 15 

Item 2. 

PROPERTIES. ................................................................................................................................. 15 

Item 3. 

LEGAL PROCEEDINGS. ............................................................................................................... 15 

Item 4. 

SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS. .................................... 15 

PART II. 

Item 5. 

MARKET FOR REGISTRANT’S COMMON EQUITY, RELATED STOCKHOLDER  
MATTERS AND ISSUER PURCHASES OF EQUITY SECURITIES. ......................................... 15 

Item 6. 

SELECTED FINANCIAL DATA. .................................................................................................. 18 

Item 7. 

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND   
RESULTS OF OPERATIONS. ........................................................................................................ 18 

Item 7A. 

QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK. ................ 25 

Item 8. 

FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA ................................................. 26 

Item 9. 

CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND  
FINANCIAL DISCLOSURE. .......................................................................................................... 50 

Item 9A. 

CONTROLS AND PROCEDURES ................................................................................................ 50 

Item 9B. 

OTHER INFORMATION ................................................................................................................ 50 

PART III. 

Item 10. 

DIRECTORS,  EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE. ........................ 50 

Item 11. 

EXECUTIVE COMPENSATION. .................................................................................................. 55 

Item 12.   

Item 13.   

SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND  
RELATED STOCKHOLDER MATTERS. ..................................................................................... 67 

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR  
INDEPENDENCE. .......................................................................................................................... 69 

Item 14. 

PRINCIPAL ACCOUNTANT FEES AND SERVICES ................................................................. 69 

PART IV. 

Item 15. 

EXHIBITS AND  FINANCIAL STATEMENT SCHEDULES ...................................................... 70 

2 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
             
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
PART I. 

ITEM 1. 

BUSINESS. 

Some of the statements contained in this Report discuss future expectations, contain projections of results 

of operations or financial condition or state other “forward-looking” information. Those statements include 
statements regarding the intent, belief or current expectations of the Company and its management team. Prospective 
investors are cautioned that any such forward-looking statements are not guarantees of future performance and 
involve risks and uncertainties, and that actual results may differ materially from those projected in the forward-
looking statements. These risks and uncertainties include but are not limited to those risks and uncertainties set forth 
under the heading “Factors That Could Affect Our Future Results” in Item 1A of this Report.  In light of the 
significant risks and uncertainties inherent in the forward-looking statements included in this Report, the inclusion 
of such statements should not be regarded as a representation by us or any other person that our objectives and plans 
will be achieved. 

General  

We are a Nevada corporation and have been in existence since 1987. Since 1994, we have positioned 

ourselves as a pharmaceutical and medical technology company with a focus on developing and commercializing 
therapeutic products based on proprietary delivery systems. We are currently focusing our efforts on new and 
patented topical pharmaceutical products based on a penetration enhancement drug delivery technology known as 
NexACT®, which may enable an active drug to be better absorbed through the skin.  

The NexACT® transdermal drug delivery technology is designed to enhance the absorption of an active 

drug through the skin, overcoming the skin's natural barrier properties and enabling high concentrations of the active 
drug to rapidly penetrate the desired site of the skin or extremity. Successful application of the NexACT® 
technology would improve therapeutic outcomes and reduce systemic side effects that often accompany oral and 
injectable medications. We have applied the NexACT® technology to a variety of compatible drug compounds and 
delivery systems, and, on our own or through development partnerships, are in various stages of developing new 
topical treatments for male and female sexual dysfunction, nail fungus, psoriasis, and other dermatological 
conditions.  We intend to continue our efforts developing topical treatments based on the application of NexACT® 
technology to drugs: (1) previously approved by the U.S. Food and Drug Administration (“FDA”), (2) with proven 
efficacy and safety profiles, (3) with patents expiring or expired and (4) with proven market track records and 
potential.   

Research and Development 

Our research and development expenses for the years ended December 31, 2008, 2007 and 2006 were 

$5,410,513, $5,022,671 and $5,425,137, respectively.  Since January 1, 1994, when we repositioned ourselves as a 
medical and pharmaceutical technology company, through December 31, 2008, we have spent $96,903,215 on 
research and development. 

NM100060 Anti-Fungal Treatment 

We have an exclusive global licensing agreement with Novartis International Pharmaceutical Ltd. 
(“Novartis”) for NM100060, our proprietary topical nail solution for the treatment of onychomycosis (nail fungal 
infection). Under the agreement, Novartis acquired the exclusive worldwide rights to NM100060 and has assumed 
all further development, regulatory, manufacturing and commercialization responsibilities as well as costs. Novartis 
agreed to pay us up to $51 million in upfront and milestone payments on the achievement of specific development 
and regulatory milestones, including an initial cash payment of $4 million at signing.  In addition, we are eligible to 
receive royalties based upon the level of sales achieved.  

The completion of patient enrollment in the Phase 3 clinical trials for NM100060 triggered a $3 million 

milestone payment from Novartis to be paid 7 months after the last patient enrolled in the Phase 3 studies.  

3 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
However, the agreement also provided that clinical milestones paid to us by Novartis would be reduced by 50% until 
we received an approved patent claim on the NM100060.  As such, we initially received only $1.5 million from 
Novartis.   

On October 17, 2008, the U.S. Patent and Trademark Office issued the Notice of Allowance on our patent 

application for NM100060.  This triggered a $2 million milestone payment from Novartis.  On October 30, 2008 we 
received a payment of $3.5 million from Novartis consisting of the balance of $1.5 million of the patient enrollment 
milestone and the $2 million patent milestone.     

In July 2008, Novartis completed testing for the Phase 3 clinical trials for NM100060.  The Phase 3 

program required for the filing of the New Drug Application (“NDA”) in the U.S. for NM100060 consisted of two 
pivotal, randomized, double-blind, placebo-controlled studies.  The parallel studies were designed to assess the 
efficacy, safety and tolerability of NM100060 in patients with mild to moderate toenail onychomycosis.  
Approximately 1,000 patients completed testing in the two studies, which took place in the U.S., Europe, Canada 
and Iceland.   On August 26, 2008, we announced that based on First Interpretable Results of these two Phase 3 
studies, Novartis had decided not to submit the NDA at this time.  As a result of this decision, we will not receive a 
$6 million milestone payment for positive Phase 3 results and a $7 million milestone payment for the filing of the 
NDA has been postponed indefinitely.  

Novartis has confirmed that it intends to complete patient testing in the ongoing comparator study which 

they had initiated in March 2007 in ten European countries.  Over 900 patients with mild to moderate 
onychomycosis are participating in this open-label study, which is designed to assess the safety and tolerability of 
NM100060 (terbinafine 10% topical formulation) versus Loceryl® (amorolfine) 5% nail lacquer, a topical treatment 
for onychomycosis that is approved in Europe. The comparator study is expected to be completed by early 2009 and 
the data will be available in mid-2009.  If the results of the comparator study are positive and the total clinical 
database is deemed to be sufficient for filing, we expect Novartis to begin filing for marketing approval in selected 
European countries while they develop a new plan of action for the U.S. market.  If the results are negative, we 
expect Novartis to terminate the global licensing agreement, which it can do at any time, and the rights to 
NM100060 would revert back to us with no compensation for termination.  

Vitaros® 

We also have under development, a topical alprostadil-based cream treatment intended for patients with 

erectile dysfunction (“Vitaros®”), which was previously known as Alprox-TD®.   Our NDA was filed and accepted 
for review by the FDA in September and November 2007, respectively.  During a teleconference with the FDA in 
early July 2008, our use of the name Vitaros® for the ED Product was verbally approved by the FDA.    

On November 1, 2007, we licensed the U.S. rights of Vitaros® to Warner Chilcott Company, Inc. 
(“Warner”).  Warner paid us $500,000 upon signing and agreed to pay us up to $12.5 million on the achievement of 
specific regulatory milestones and to undertake the manufacturing investment and any other investment for further 
product development that may be required for product approval.  Additionally, Warner was responsible for the 
commercialization and manufacturing of Vitaros®.   

On July 21, 2008, we received a not approvable action letter (the “Action Letter”) from the FDA in 

response to our NDA.  The major regulatory issues raised by the FDA were related to the results of the transgenic 
(“TgAC”) mouse carcinogenicity study which NexMed completed in 2002.   The TgAC concern raised by the FDA 
is product specific, and does not affect the dermatological products in our pipeline, specifically NM100060.    

On October 15, 2008, we met with the FDA to discuss the major deficiencies cited in the Action Letter and 

to reach consensus on the necessary actions for addressing these deficiencies for our Vitaros® NDA.  Several key 
regulatory concerns were addressed and agreements were reached at the meeting. The FDA agreed to: (a) a review 
by the Carcinogenicity Advisory Committee (CAC) of the 2 two-year carcinogenicity studies which were recently 
completed; (b) one Phase 1 study in healthy volunteers to assess any transfer to the partner of the NexACT® 
technology and (c) one animal study to assess the transmission of sexually transmitted diseases with the design of 

4 

 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
the study to be determined.  The FDA also confirmed the revision on the status of our manufacturing facility from 
“withhold” to “acceptable”, based on our adequately addressing the deficiencies cited in their Pre-Approval 
Inspection (“PAI”) of our facility in January 2008.  It is also our understanding that at this time the FDA does not 
require a one-year open-label safety study for regulatory approval.  After the meeting we estimated that an 
additional $4 to $5 million would be needed to be spent to complete the abovementioned requirements prior to the 
resubmission of the NDA.  

 On February 3, 2009, we announced the sale of the U.S. rights for Vitaros®  and the specific U.S. patents 

covering Vitaros®  to Warner which effectively terminated the previous licensing agreement.   Under the terms of the 
agreement, we received gross proceeds of $2.5 million as an up-front payment and are eligible to receive an 
additional payment of $2.5 million upon Warner’s receipt of an NDA approval from the FDA.  In addition, Warner 
will pay a total of $350,000 for the manufacturing equipment for Vitaros®.  The purchase agreement with Warner 
gives us the right to reference their work on Vitaros® in our future filings outside the U.S.  This is important as we 
move ahead with international partnering opportunities because the additional data may further validate the safety of 
the product and enhance its potential value.  While it is our understanding that Warner is currently moving forward 
in pursuing NDA approval for Vitaros®, they are not obligated by the purchase agreement to continue with the 
development of Vitaros® and the filing of the NDA.   

On  February  21,  2007,  the  Canadian  regulatory  authority,  Health  Canada,  informed  us  that  the  lack  of  a 
completed 12-month open label safety study would not preclude them from accepting and reviewing our New Drug 
Submission  (“NDS”)  in  Canada,  which  was  accepted  for  review  on  February  15,  2008.    On  May  2,  2008,  we 
announced that our manufacturing facility received a GMP compliance certification from Health Canada, which is 
essential  for  the  ultimate  approval  and  marketing  of  Vitaros®  in  Canada.    We  received  a  Letter  of  Deficiences 
(“LOD”) on November 12, 2008 which cited similar regulatory issues as previously cited by the FDA.  On February 
18, 2009 we responded to the LOD.  There is no assurance that our response will be sufficient to convince Health 
Canada to approve our product.  

On  April  20,  2007,  the  United  Kingdom  regulatory  authority,  Medicines  and  Healthcare  Products 
Regulatory  Agency  (the  “MHRA”),  also  informed  us  that  the  safety  data  that  we  have  compiled  to  date  was 
sufficient for the Marketing Authorization Application (“MAA”) to be filed and accepted for review in the United 
Kingdom.  We had another guidance meeting with the MHRA in January 2008 and received additional input for the 
preparation of our MAA.  However, the MHRA has recently informed us that due to the backlog of MAA filings, 
they would not be able to receive and start reviewing our MAA until October 2010.  Even though we are encouraged 
by the initial positive feedback from the MHRA, the risk remains that we may not be successful in convincing the 
MHRA and other European regulatory authorities to approve our product for marketing.  

Femprox® and Other Products 

We are also developing Femprox®, which is an alprostadil-based cream product intended for the treatment 
of female sexual arousal disorder. We have completed nine clinical studies to date, including one 98-patient Phase 2 
study in the U.S. for Femprox®, and also a 400-patient study for Femprox® in China, where the cost for conducting 
clinical studies is significantly lower than in the U.S.  We do not intend to conduct additional studies for this product 
until we have secured a co-development partner, which we are actively seeking. 

We have also continued early stage development work for our product pipeline with the goal of focusing 

our attention on product opportunities that would replicate the model of our licensed anti-fungal nail treatment.  Our 
current efforts are focused on the development of viable topical treatments for psoriasis, a common dermatological 
condition.    

Restructuring Plans 

In December 2008, we began to implement a restructuring program with the goal of reducing costs and 

outsourcing basic research and development.  As part of our restructuring plan, we announced on January 22, 2009 a 
memorandum of understanding (“MOU”) with Pharmaceutics International, Inc. or Pii.   The purpose of this 
collaboration is to broaden the promotion of our technology as well as permit us access to Pii’s research and 
development and commercial manufacturing infrastructure. Pii is a privately-held contract research and 

5 

 
 
 
 
 
 
 
 
 
 
     
 
 
 
 
 
 
manufacturing organization with over 400 employees located near Baltimore, Maryland.  Their capabilities range 
from product research and development to commercial manufacturing.  Pursuant to our MOU, Pii will promote our 
NexACT technology to its clients and may independently identify new product development opportunities for this 
collaboration with NexMed.  We will provide technical guidance and oversight in the development of new products.  
In addition, as part of our restructuring plan, we are discussing with Pii the opportunity to co-develop our early stage 
products which will enable us to further reduce our monthly overhead expenses.   

The partnership with Pii allows us to continue the development of our early stage projects while we reduce 

our  research and development staff and infrastructure.  As a result, we expect to see our monthly operating 
overhead burn rate reduced to approximately $300,000 per month by the end of the first quarter of 2009.  Access to 
Pii’s state of the art facilities also allows us to further improve our cash position by selling our facility and redundant 
equipment.  We plan to sell our facility during 2009 which would further reduce our monthly operating expenses to 
approximately $200,000 per month after the sale of the facility is completed. 

During 2009, we plan to work with Pii to complete the development of the psoriasis project and then 

license the product to a co-development and marketing partner.  We also plan to license the rights to Vitaros®   for 
territories outside the U.S., including Canada, South America, and Europe.  The purchase agreement with Warner 
gives us the right to reference their work on Vitaros® in our future filings outside the U.S.  This is important as we 
move ahead with international partnering opportunities because the additional data may further validate the safety of 
the product and enhance its potential value.  Additionally, the future work done by Warner regarding the safety of 
Vitaros®                             may enhance the value of Femprox®  as we work to find a marketing and co-development 
partner during 2009.  In addition, we remain open to opportunities to co-develop products utilizing our NexACT 
technology and we will be actively pursuing strategic opportunities that would leverage our NexACT platform and 
generate partnership revenues to fund our development efforts.    

Patents 

We have either acquired or received thirteen U.S. patents out of a series of patent applications that we have 

filed in connection with our NexACT® technology and our NexACT® -based products under development. To 
further strengthen our global patent position on our proprietary products under development, and to expand the 
patent protection to other markets, we have filed under the Patent Cooperation Treaty corresponding international 
applications for our issued U.S. patents and pending U.S. patent applications.  

The following table identifies the thirteen U.S. patents issued for NexACT® technology and/or our 

NexACT®-based products under development, and the year of expiration for each patent: 

Patent Name 

Expiration Date

Biodegradable Absorption Enhancers *** 
Biodegradable Absorption Enhancers ****   
Compositions and Methods for Amelioration of Human Female Sexual Dysfunction 
Topical Compositions for PGE1 Delivery 
Topical Compositions for Non-Steroidal Anti-Inflammatory Drug Delivery 
Prostaglandin Composition and Methods of Treatment of Male Erectile Dysfunction ** 
Medicament Dispenser 
Crystalline Salts of dodecyl 2-(N, N-Dimethylamino)-propionate * 
Topical Compositions Containing Prostaglandin E1 
CIP: Topical Compositions Containing Prostaglandin E1 
Prostaglandin Composition and Methods of Treatment of Male Erectile Dysfunction ** 
CIP: Prostaglandin Composition and Methods of Treatment of Male Erectile Dysfunction ** 
Topical Stabilized Prostaglandin E Compound Dosage Forms 

2008 
2009 
2017 
2017 
2017 
2017 
2019 
2019 
2019 
2019 
2020 
2020 
2023 

* Composition of matter patent on our NexACT® technology 

6 

 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
** Sold to Warner on February 3, 2009 

*** Expired June 1, 2008 

**** Expired on January 21, 2009 

  While we have obtained patents and have several patent applications pending, the extent of effective patent 
protection in the U.S. and other countries is highly uncertain and involves complex legal and factual questions.  No 
consistent policy addresses the breadth of claims allowed in or the degree of protection afforded under patents of 
medical and pharmaceutical companies.  Patents we currently own or may obtain might not be sufficiently broad to 
protect us against competitors with similar technology.  Any of our patents could be invalidated or circumvented. 

While we believe that our patents would prevail in any potential litigation, the holders of competing patents 

could determine to commence a lawsuit against us and even prevail in any such lawsuit.  Litigation could result in 
substantial cost to and diversion of effort by us, which may harm our business. In addition, our efforts to protect or 
defend our proprietary rights may not be successful or, even if successful, may result in substantial cost to us.  
Additionally, we have indemnified Warner against challenges to the patents that they acquired from us on February 
3, 2009. 

Segment and Geographic Area Information 

You can find information about our business segment and geographic areas of business in Note 16 of the 

Notes to Consolidated Financial Statements in Item 8. 

Employees 

As of March 12, 2009, we had 13 full time employees, 3 of whom are executive management and 4 of whom 

are engaged in research and development activities.   We also rely on a number of consultants.  None of our 
employees are represented by a collective bargaining agreement.  We believe that we have a good relationship with 
our employees.  

Executive Officers of the Registrant 

The Executive Officers of the Company are set forth below. 

Name 

Age* 

Title 

Vivian H. Liu 

Hemanshu Pandya 

Mark Westgate 

*As of March 1, 2009 

47 

37 

39 

Director, President and Chief Executive Officer and Secretary 

Vice President and Chief Operating Officer 

Vice President and Chief Financial Officer and Treasurer 

Vivian H. Liu is, and has been, our President and Chief Executive Officer since June 2007 and Secretary 

since 1995, and also a Director of the Company since June 2007.  Ms. Liu served as the Company’s Executive Vice 
President and Chief Operating Officer from January 2006 to June 2007,  Vice President of Corporate Affairs from 
September 1995 until December 2005, Acting Chief Executive Officer from December 2005 until January 2006, 
Chief Financial Officer from January 2004 until December 2005, Acting Chief Financial Officer from 1999 to 
January 2004 and Treasurer from September 1995 through December 2005.  In 1994, while the Company was in a 

7 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
transition period, Ms. Liu served as Chief Executive Officer. From 1985 to 1994, Ms. Liu was a business and 
investment adviser to the government of Quebec and numerous Canadian companies with respect to product 
distribution, technology transfer and investment issues. Ms. Liu received her MPA in International Finance from the 
University of Southern California and her B.A. from the University of California, Berkeley.  

Hemanshu Pandya is, and has been, our Vice President and Chief Operating Officer since October 2007.  

Mr. Pandya most recently served as Chief Commercial Officer for Putney, Inc., a start-up veterinary pharmaceutical 
company, from March 2007 to July 2007.  From August 2005 to December 2006, and prior to its merger with 
Watson Pharmaceuticals, Inc., Mr. Pandya was Senior Vice President of Business Development and Strategic 
Alliances for Andrx Pharmaceuticals, Inc., where he managed the licensing and co-development opportunities with 
strategic global partners.  From August 2002 to August 2005, Mr. Pandya served as Vice President of Corporate 
Development and Commercial Operations for Able Laboratories, Inc.  Prior to August 2002, Mr. Pandya served in 
various senior management positions with Ivax Pharmaceuticals, Inc. and Faulding/Purepac Pharmaceutical 
Company (subsequently Alpharma, Inc.).   He received his Bachelor’s Degree from Rutgers University. 

Mark Westgate is, and has been, our Vice President, Chief Financial Officer and Treasurer since December 
2005.  From March 2002 to December 2005, Mr. Westgate served as our Controller.  He has over seventeen years of 
public accounting and financial management experience.  From August 1998 to March 2002, Mr. Westgate served 
as Controller and Director of Finance for Lavipharm Laboratories Inc., a company specializing in drug delivery and 
particle design.  Prior to joining Lavipharm, he was a supervisor at Richard A. Eisner & Company, LLP where he 
performed audits and provided tax advice for clients in various industries including biotech.  Mr. Westgate is a 
Certified Public Accountant and a member of the New York State Society of Certified Public Accountants.  He 
holds a B.B.A. in public accounting from Pace University. 

WHERE YOU CAN FIND MORE INFORMATION 

We file annual, quarterly and special reports, proxy statements and other information with the Securities 

and Exchange Commission, and we have an Internet website address at http://www.nexmed.com. We make 
available free of charge on our Internet website address our annual report on Form 10-K, quarterly reports on Form 
10-Q, current reports on Form 8-K, and amendments to those reports filed or furnished pursuant to Sections 13(a) or 
15(d) of the Exchange Act as well as our proxy statements as soon as reasonably practicable after we electronically 
file such material with, or furnish it to, the SEC.  You may also read and copy any document we file at the Securities 
and Exchange Commission's public reference room located at 100 F Street, N.E., Washington, D.C. 20549. Please 
call the Securities and Exchange Commission at 1-800-732-0330 for further information on the operation of such 
public reference room. You also can request copies of such documents, upon payment of a duplicating fee, by 
writing to the Securities and Exchange Commission at 450 Fifth Street, N.W., Washington, D.C. 20549 or obtain 
copies of such documents from the Securities and Exchange Commission's website at http://www.sec.gov.   

ITEM 1A. 

RISK FACTORS. 

FACTORS THAT COULD AFFECT OUR FUTURE RESULTS 

RISKS RELATED TO THE COMPANY 

We continue to require external financing to fund our operations, which may not be available. 

Our current cash reserves provide us with sufficient cash to fund our operations into the first quarter of 
2010.  We will need additional sources of cash to fund the development and eventual marketing and sales of our 
psoriasis product, Femprox®, and Vitaros®   in territories outside of the U.S.  We intend to seek development 
partners to advance our products under development because we will also need significant funding to pursue our 
overall product development plans. In general, products we plan to develop will require significant time-consuming 
and costly research and development, clinical testing, regulatory approval and significant investment prior to their 
commercialization. Even if we are successful in obtaining partners who can assume the funding for further 
development of our products, we may still encounter additional obstacles such as research and development 

8 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
activities may not be successful, our products may not prove to be safe and effective, clinical development work 
may not be completed, and the anticipated products may not be commercially viable or successfully marketed.  

In July 2008, Novartis completed testing for the Phase 3 clinical trials for NM100060.  The Phase 3 
program required for the filing of the NDA in the U.S. for NM100060 consisted of two pivotal, randomized, double-
blind, placebo-controlled studies.  The parallel studies were designed to assess the efficacy, safety and tolerability of 
NM100060 in patients with mild to moderate toenail onychomycosis.  Approximately 1,000 patients completed 
testing in the two studies, which took place in the U.S., Europe, Canada and Iceland.   On August 26, 2008, we 
announced that based on First Interpretable Results of these two Phase 3 studies, Novartis had decided not to submit 
the NDA at this time.  As a result of this decision, we will not receive a $6 million payment for positive Phase 3 
results.  In addition, a $7 million milestone payment for the filing of the NDA has been postponed indefinitely.  

Novartis has confirmed that it intends to complete patient testing in the ongoing comparator study which 

they had initiated in March 2007 in ten European countries.  Over 900 patients with mild to moderate 
onychomycosis are participating in this open-label study, which is designed to assess the safety and tolerability of 
NM100060 (terbinafine 10% topical formulation) versus Loceryl® (amorolfine) 5% nail lacquer, a topical treatment 
for onychomycosis that is approved in Europe. The comparator study is expected to be completed by early 2009 and 
the data will be available in mid-2009.  If the results of the comparator study are positive and the total clinical 
database is deemed to be sufficient for filing, we expect Novartis to begin filing for marketing approval in selected 
European countries while they develop a new plan of action for the U.S. market.  If the results are negative, we 
expect Novartis to terminate the global licensing agreement, which it can do at any time, and the rights to 
NM100060 would revert back to us with no compensation for termination.  

On February 3, 2009, we terminated the licensing agreement and sold the U.S. rights for Vitaros®  and the 

specific U.S. patents covering Vitaros®  to Warner.  Under the terms of the agreement, we received gross proceeds of 
$2.5 million as an up-front payment and are eligible to receive an additional payment of $2.5 million upon Warner’s 
receipt of an NDA approval from the FDA.  As such, we are no longer responsible for the regulatory approval of 
Vitaros®   and will no longer be eligible to receive royalties in the future based upon the level of sales achieved by 
Warner.  In addition, Warner will pay a total of $350,000 for the manufacturing equipment for Vitaros®. 

Our current cash reserves of approximately $4.5 million as of the date of this report, which includes the 

$2.5 million received from Warner on February 3, 2009, should provide us with sufficient cash to fund our 
operations into the first quarter of 2010.  This projection is based on the restructuring plan we implemented in 
December 2008 whereby we have reduced our current monthly operating expenditures to $350,000 and plan to 
further reduce these expenditures to approximately $300,000 per month by the second quarter of 2009.  In addition, 
as part of our restructuring plan, we are discussing with Pii the opportunity to co-develop our early stage products 
which will enable us to further reduce our monthly overhead expenses and allow us to sell our facility and redundant 
equipment.  We have also initiated efforts to sell the facility housing our corporate office, research and development 
laboratories and manufacturing plant located in East Windsor, New Jersey.  If we can successfully sell our facility 
and repay the existing mortgage, we should be able to reduce our monthly operating expenditures to approximately 
$200,000 per month.  However, there is no assurance that we will be able to sell our facility at an acceptable price or 
otherwise successfully complete our restructuring plan.   

Our principal product under development, NM100060, has not met Novartis’ expectation for filing a New 
Drug Application in the U.S., and, depending upon European comparator study results, Novartis may 
terminate its global licensing agreement with us. 

In September 2005, we announced a global licensing agreement with Novartis, pursuant to which Novartis 

acquired the exclusive worldwide rights to NM100060, our topical anti-fungal nail treatment product.  While 
Novartis has decided not to submit an NDA for NM100060 to the FDA at this time, it has confirmed that it intends 
to complete a European comparator study.  If positive results are achieved, we expect Novartis to obtain regulatory 
approval of NM100060 in selected countries in Europe.  If the results are negative, we expect Novartis to terminate 
the global licensing agreement with the rights to NM100060 reverting to us.  

9 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Our  near-term  prospects  for  deriving  any  return  on  our  investments  in  NM100060  and  Vitaros®  are 
dependent upon decisions to be made by Novartis and Warner in their discretion. 

We are dependent upon Novartis to complete its European comparator study and obtain regulatory approval 
in  Europe  for  us  to  derive  any  near-term  return  on  our  investment  in  the  development  of  NM100060.    While  we 
expect Novartis to do both, it is not required by any agreement with us to do either.  For us to derive any near-term 
return  on  our  investment  in  the  development  of  Vitaros®,  we  are  dependent  upon  Warner  to  move  forward  in 
pursuing NDA approval for Vitaros® in the U.S., which it is not required to do.  While if Novartis elects to terminate 
the  global  licensing  agreement,  the  rights  to  NM100060  will  revert  to  us,  and  if  we  are  to  derive  revenue  from 
NM100060  in  the  future,  we  will  need  to  find  new  development  partners.    As  for  Vitaros®,  if  Warner  does  not 
pursue NDA approval for Vitaros®, we will not have the additional data generated by Warner to enhance the value 
of  the  product  for  non-U.S.  development  partners  which  may  make  it  more  difficult  to  find  such  development 
partners.  In either case, it may not be possible for us to enter into such partner relationships in a timely manner, if at 
all.   

We will continue to incur operating losses. 

Our current business operations began in 1994 and we have a limited operating history.  We may encounter 

delays, uncertainties and complications typically encountered by development stage businesses. We have not 
marketed or generated revenues in the U.S. from our products under development. We are not profitable and have 
incurred an accumulated deficit of $139,689,300 since our inception and through December 31, 2008. Our ability to 
generate revenues and to achieve profitability and positive cash flow will depend on the successful licensing or 
commercialization of our products currently under development. However, even if we eventually generate revenues 
from sales of our products currently under development or from licensing fees, we expect to incur significant 
operating losses over the next several years. Our ability to become profitable will depend, among other things, on 
our (1) development of our proposed products, (2) obtaining of regulatory approvals of our proposed products on a 
timely basis and (3) success in licensing, manufacturing, distributing and marketing our proposed products.  

Our independent registered public accounting firm has doubt as to our ability to continue as a going concern.   

As a result of our losses to date, expected losses in the future, limited capital resources and accumulated 

deficit, our independent registered public accounting firm has concluded that there is substantial doubt as to our 
ability to continue as a going concern, and accordingly, our independent registered public accounting firm has 
modified their report on our December 31, 2008 consolidated financial statements included in this annual report on 
Form 10-K in the form of an explanatory paragraph describing the events that have given rise to this uncertainty. 
These factors may make it more difficult for us to obtain additional funding to meet our obligations. Our 
continuation is dependent upon our ability to generate or obtain sufficient cash to meet our obligations on a timely 
basis and ultimately to attain profitable operations. We anticipate that we will continue to incur significant losses at 
least until successful commercialization of one or more of our products, and we may never operate profitably in the 
future.  

We will need partnering agreements and significant funding to continue with our research and development 
efforts, and they may not be available. 

Our current cash reserves provide us with sufficient cash to fund our operations into the first quarter of 
2010.  We will need additional sources of cash to fund the development and eventual marketing and sales of our 
psoriasis product, Femprox®, and Vitaros®   in territories outside of the U.S.  We intend to seek development 
partners to advance our products under development because we will also need significant funding to pursue our 
overall product development plans. In general, products we plan to develop will require significant time-consuming 
and costly research and development, clinical testing, regulatory approval and significant investment prior to their 
commercialization.  

Our research and development expenses for the years ended December 31, 2008, 2007 and 2006 were 

$5,410,513, $5,022,671 and $5,425,137, respectively.  Since January 1, 1994, when we repositioned ourselves as a 

10 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
medical and pharmaceutical technology company, through December 31, 2008, we have spent $96,903,215 on 
research and development.  Given our current level of cash reserves and low rate of revenue generation, we will not 
be able to fully advance our products under development unless we enter into additional partnering agreements. If 
we are successful in entering into additional partnering agreements for our products under development, we may 
receive milestone payments, which will offset some of our research and development expenses. 

We currently have no sales force or marketing organization and will need, but may not be able, to attract 
marketing partners or afford qualified or experienced marketing and sales personnel. 

In order to market our proprietary products under development, we will need to attract additional marketing 

partner(s) that will need to spend significant funds to inform potential customers, including third-party distributors, 
of the distinctive characteristics and benefits of our products. Our operating results and long term success will 
depend, among other things, on our ability to establish (1) successful arrangements with domestic and additional 
international distributors and marketing partners and (2) an effective internal marketing organization.  
Consummation of partnering arrangements is subject to the negotiation of complex contractual relationships, and we 
may not be able to negotiate such agreements on a timely basis, if at all, or on terms acceptable to us. 

Pre-clinical and clinical trials are inherently unpredictable.  If we or our partners do not successfully conduct 
these trials, we or our partners may be unable to market our products. 

Through pre-clinical studies and clinical trials, our products must be demonstrated to be safe and effective 

for their indicated uses. Results from pre-clinical studies and early clinical trials may not allow for prediction of 
results in later-stage testing.  Future clinical trials may not demonstrate the safety and effectiveness of our products 
or may not result in regulatory approval to market our products.  Commercial sales in the United States of our 
products cannot begin until final FDA approval is received.  The failure of the FDA to approve our products for 
commercial sales will have a material adverse effect on our prospects. 

Patents and intellectual property rights are important to us but could be challenged. 

Proprietary protection for our pharmaceutical products is of material importance to our business in the U.S. 

and most other countries. We have sought and will continue to seek proprietary protection for our products to 
attempt to prevent others from commercializing equivalent products in substantially less time and at substantially 
lower expense. Our success may depend on our ability to (1) obtain effective patent protection within the U.S. and 
internationally for our proprietary technologies and products, (2) defend patents we own, (3) preserve our trade 
secrets, and (4) operate without infringing upon the proprietary rights of others.  In addition, we have agreed to 
indemnify our partners for certain liabilities with respect to the defense, protection and/or validity of our patents and 
would also be required to incur costs or forego revenue if it is necessary for our partners to acquire third party patent 
licenses in order for them to exercise the licenses acquired from us. 

We have either acquired or received thirteen U.S. patents out of a series of patent applications that we have 
filed in connection with our NexACT® technology and our NexACT®-based products under development. To further 
strengthen our global patent position on our proprietary products under development, and to expand the patent 
protection to other markets, we have filed under the Patent Cooperation Treaty corresponding international 
applications for our issued U.S. patents and pending U.S. patent applications.  The two patents covering the first 
generation of the NexACT® technology enhancer have expired, and we have sold three patents covering Vitaros®  to 
Warner.  While we believe there are significant disadvantages to using the permeation enhancers that are covered by 
the two patents which expired in 2008 and 2009, including the difficulty of formulation, there is always a risk that 
once our enhancers are off patent, they can be used by other parties to develop competitive products.     

  While we have obtained patents and have several patent applications pending, the extent of effective patent 
protection in the U.S. and other countries is highly uncertain and involves complex legal and factual questions.  No 
consistent policy addresses the breadth of claims allowed in or the degree of protection afforded under patents of 
medical and pharmaceutical companies.  Patents we currently own or may obtain might not be sufficiently broad 
enough to protect us against competitors with similar technology.  Any of our patents could be invalidated or 
circumvented. 

11 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  While we believe that our patents would prevail in any potential litigation, the holders of competing patents 

could determine to commence a lawsuit against us and even prevail in any such lawsuit.  Litigation could result in 
substantial cost to and diversion of effort by us, which may harm our business. In addition, our efforts to protect or 
defend our proprietary rights may not be successful or, even if successful, may result in substantial cost to us. 
Additionally, we have indemnified Warner against challenges to the patents that they acquired from us on February 
3, 2009. 

We and our licensees depend upon third party manufacturers for chemical manufacturing supplies. 

  We and our licensees are dependent on third party chemical manufacturers for the active drugs in our 
NexACT®-based products under development, and for the supply of our NexACT® enhancers that are essential in 
the formulation and production of our topical products on a timely basis and at satisfactory quality levels.  If our 
validated third party chemical manufacturers fail to produce quality products on time and in sufficient quantities, our 
results would suffer, as we or our licensees would encounter costs and delays in revalidating new third party 
suppliers. 

We face severe competition. 

We are engaged in a highly competitive industry. We and our licensees can expect competition from 

numerous companies, including large international enterprises, and others entering the industry with regard to our 
products. Most of these companies have greater research and development, manufacturing, marketing, financial, 
technological, personnel and managerial resources. Acquisitions of competing companies by large pharmaceutical or 
healthcare companies could further enhance such competitors' financial, marketing and other resources. Competitors 
may complete clinical trials, obtain regulatory approvals and commence commercial sales of their products before 
we could enjoy a significant competitive advantage. Products developed by our competitors may be more effective 
than our products.  

We may be subject to potential product liability and other claims, creating risks and expense.   

 We are also exposed to potential product liability risks inherent in the development, testing, 
manufacturing, marketing and sale of human therapeutic products.  Product liability insurance for the 
pharmaceutical industry is extremely expensive, difficult to obtain and may not be available on acceptable terms, if 
at all. We currently have liability insurance to cover claims related to our products that may arise from clinical trials, 
with coverage of $1 million for any one claim and coverage of $3 million in total, but we do not maintain product 
liability insurance for marketed products as our products have yet to be commercialized.  We may need to acquire 
such insurance coverage prior to the commercial introduction of our products. If we obtain such coverage, we have 
no guarantee that the coverage limits of such insurance policies will be adequate. A successful claim against us if we 
are uninsured, or which is in excess of our insurance coverage, if any, could have a material adverse effect upon us 
and on our financial condition. 

INDUSTRY RISKS 

We are vulnerable to volatile market conditions. 

The market prices for securities of biopharmaceutical and biotechnology companies, including ours, have 
been highly volatile. The market has from time to time experienced significant price and volume fluctuations that 
are unrelated to the operating performance of particular companies. In addition, future announcements, such as the 
results of testing and clinical trials, the status of our relationships with third-party collaborators, technological 
innovations or new therapeutic products, governmental regulation, developments in patent or other proprietary 
rights, litigation or public concern as to the safety of products developed by us or others and general market 
conditions, concerning us, our competitors or other biopharmaceutical companies, may have a significant effect on 
the market price of our Common Stock. 

12 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Instability and volatility in the financial markets and the global economic recession are likely to have a 
negative impact on our ability to raise necessary funds and on our business, financial condition, results of 
operations and cash flows. 

During recent months, there has been substantial volatility and a decline in financial markets due at least in 
part  to  the  deteriorating  global  economic  environment.  In  addition,  there  has  been  substantial  uncertainty  in  the 
capital markets and access to financing is uncertain.  These conditions are likely to have an adverse effect on our 
industry, licensing partners, and business, including our financial condition, results of operations and cash flows.  

To the extent that we do not generate sufficient cash from operations, we may, if available, need to incur 
indebtedness to finance plans for growth. However, recent turmoil in the credit markets and the potential impact on 
the liquidity of major financial institutions may have an adverse effect on our ability to fund our business strategy 
through borrowings, under either existing or newly created instruments in the public or private markets on terms that 
we believe to be reasonable, if at all.   

We and our licensees are subject to numerous and complex government regulations which could result in 
delay and expense. 

Governmental authorities in the U.S. and other countries heavily regulate the testing, manufacture, labeling, 

distribution, advertising and marketing of our proposed products. None of our proprietary products under 
development has been approved for marketing in the U.S. Before any products we develop are marketed, FDA and 
comparable foreign agency approval must be obtained through an extensive clinical study and approval process. 

The studies involved in the approval process are conducted in three phases.  In Phase 1 studies, researchers 

assess safety or the most common acute adverse effects of a drug and examine the size of doses that patients can 
take safely without a high incidence of side effects. Generally, 20 to 100 healthy volunteers or patients are studied in 
the Phase 1 study for a period of several months. In Phase 2 studies, researchers determine the drug's efficacy with 
short-term safety by administering the drug to subjects who have the condition the drug is intended to treat, assess 
whether the drug favorably affects the condition, and begin to identify the correct dosage level. Up to several 
hundred subjects may be studied in the Phase 2 study for approximately 6 to 12 months, depending on the type of 
product tested. In Phase 3 studies, researchers further assess efficacy and safety of the drug. Several hundred to 
thousands of patients may be studied during the Phase 3 studies for a period from 12 months to several years. Upon 
completion of Phase 3 studies, a New Drug Application is submitted to the FDA or foreign governmental regulatory 
authority for review and approval. 

The failure to obtain requisite governmental approvals for our products under development in a timely 

manner or at all would delay or preclude us and our licensees from marketing our products or limit the commercial 
use of our products, which could adversely affect our business, financial condition and results of operations. 

Because we intend that our products will be sold and marketed outside the U.S., we and/or our licensees 

will be subject to foreign regulatory requirements governing the conduct of clinical trials, product licensing, pricing 
and reimbursements. These requirements vary widely from country to country. The failure to meet each foreign 
country's requirements could delay the introduction of our proposed products in the respective foreign country and 
limit our revenues from sales of our proposed products in foreign markets. 

Successful commercialization of our products may depend on the availability of reimbursement to the 

consumer from third-party healthcare payers, such as government and private insurance plans. Even if one or more 
products is successfully brought to market, reimbursement to consumers may not be available or sufficient to allow 
the realization of an appropriate return on our investment in product development or to sell our products on a 
competitive basis. In addition, in certain foreign markets, pricing or profitability of prescription pharmaceuticals is 
subject to governmental controls. In the U.S., federal and state agencies have proposed similar governmental control 
and the U.S. Congress has recently considered legislative and regulatory reforms that may affect companies engaged 
in the healthcare industry. Pricing constraints on our products in foreign markets and possibly in the U.S. could 
adversely affect our business and limit our revenues. 

13 

 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
RISKS RELATED TO OWNING OUR COMMON STOCK 

Our stock may be delisted from Nasdaq, which may make it more difficult for you to sell your shares. 

Currently, our Common Stock trades on the Nasdaq Capital Market.  On October 9, 2008, we were notified 

by The Nasdaq Stock Market (“Nasdaq”) that for the previous 30 consecutive trading days our Common Stock has 
closed below the minimum $1.00 per share requirement for continued inclusion by Marketplace Rule 4310(c)(8)(D).  
Pursuant to Marketplace Rule 4310(c)(8)(E), we were provided 180 calendar days, or until April 7, 2009, to regain 
compliance.   

On October 22, 2008, we were notified by Nasdaq that effective October 16, 2008 it had suspended 

enforcement of the bid price requirement until January 16, 2009.  Further, on December 23, 2008 we were notified 
by Nasdaq that it had again suspended the enforcement of the bid price requirement until April 20, 2009.  As such, 
since we had 174 days remaining in our compliance period, we now have 174 days from April 20, 2009, or until 
October 10, 2009, to regain compliance. 

Accordingly, our Common Stock must achieve a minimum bid price of $1.00 for a minimum of 10 

consecutive days during the period ended October 10, 2009 in order to maintain our listing on the Nasdaq Capital 
Market.    

If we fail to achieve the minimum bid price requirement of the Nasdaq Capital Market by October 10, 2009 

or fail to maintain compliance with any other listing requirements during this period, we may be delisted and our 
stock would be considered a penny stock under regulations of the Securities and Exchange Commission and would 
therefore be subject to rules that impose additional sales practice requirements on broker-dealers who sell our 
securities. The additional burdens imposed upon broker-dealers by these requirements could discourage broker-
dealers from effecting transactions in our Common Stock, which could severely limit the market liquidity of the 
Common Stock and your ability to sell our securities in the secondary market. In addition, if we fail to maintain our 
listing on Nasdaq or any other United States securities exchange, quotation system, market or over-the-counter 
bulletin board, we will be subject to cash penalties under investor rights agreements to which we are a party until a 
listing is obtained. 

We do not expect to pay dividends on our Common Stock in the foreseeable future.  

Although our shareholders may receive dividends if, as and when declared by our board of directors, we do 
not intend to declare dividends on our Common Stock in the foreseeable future. Therefore, you should not purchase 
our Common Stock if you need immediate or future income by way of dividends from your investment. 

We may issue additional shares of our capital stock that could dilute the value of your shares of Common 
Stock. 

We are authorized to issue 130,000,000 shares of our capital stock, consisting of 120,000,000 shares of our 

Common Stock and 10,000,000 shares of our preferred stock of which 1,000,000 are designated as Series A Junior 
Participating Preferred Stock, 800 are designated as Series B 8% Cumulative Convertible Preferred Stock and 600 
are designated as Series C 6% Cumulative Convertible Preferred Stock. As of March 10, 2009, 84,410,736 shares of 
our Common Stock were issued and outstanding and 15,487,035 shares of our Common Stock were issuable upon 
the exercise or conversion of outstanding options and warrants.  As of March 10, 2009, there were no shares of 
Series A, Series B or Series C Preferred Stock outstanding.  In light of our possible future need for additional 
financing, we may issue authorized and unissued shares of Common Stock at below current market prices or 
additional convertible securities that could dilute the earnings per share and book value of your shares of our 
Common Stock. 

In addition to provisions providing for proportionate adjustments in the event of stock splits, stock 
dividends, reverse stock splits and similar events, certain warrants, provide (with certain exceptions) for an 
adjustment of the exercise price if we issue shares of Common Stock at prices lower than the then exercise or 

14 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
conversion price or the then prevailing market price. This means that if we need to raise equity financing at a time 
when the market price for our Common Stock is lower than the exercise or conversion price, or if we need to 
provide a new equity investor with a discount from the then prevailing market price, then the exercise price will be 
reduced and the dilution to shareholders increased. 

ITEM 1B. 

UNRESOLVED STAFF COMMENTS. 

None. 

ITEM 2. 

PROPERTIES. 

We currently have our corporate office, laboratories and manufacturing plant in a 31,500 square foot 

facility in East Windsor, NJ, which we own.  We have invested approximately $9.4 million for the land, building 
and upgrade.  The facility is subject to a mortgage as discussed in Note 6 of the Consolidated Financial Statements.   
We have also recently initiated efforts to sell the facility and have taken an impairment charge of approximately 
$884,000 in 2008. 

ITEM 3. 

LEGAL PROCEEDINGS. 

We are subject to certain legal proceedings in the ordinary course of business.  We do not expect any such 

items to have a significant impact on our financial position. 

ITEM 4. 

SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS. 

No matters were submitted to a vote of security holders during the fourth quarter of 2008. 

PART II. 

ITEM 5. 

MARKET FOR REGISTRANT’S COMMON EQUITY, RELATED STOCKHOLDER 
MATTERS AND ISSUER PURCHASES OF EQUITY SECURITIES. 

Our Common Stock is traded on the NASDAQ Capital Market System (“NASDAQ”) under the symbol 

“NEXM.”  

On March 10, 2009, the last reported sales price for our Common Stock on NASDAQ was $0.11 per share, 

and we had 7,623 holders of record of our Common Stock.   

The following table sets forth the range of the high and low sales prices for our Common Stock as reported 

by NASDAQ for each quarter from January 1, 2007 to December 31, 2008. 

Price of Common Stock ($) 

2008 
First Quarter 
Second Quarter  
Third Quarter  
Fourth Quarter 

Low 

1.19 
1.04 
0.12 
0.05 

High 

1.70 
1.37 
1.53 
0.16 

15 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
2007 
First Quarter 
Second Quarter  
Third Quarter  
Fourth Quarter 

Dividends 

1.54 
2.05 
1.90 
1.71 

0.72 
1.24 
1.47 
1.34 

We have never paid cash dividends on our Common Stock and do not have any plans to pay cash dividends 

in the foreseeable future.  Our board of directors anticipates that any earnings that might be available to pay 
dividends will be retained to finance our business. 

Performance  comparison  of  total  return  of  NexMed,  Inc.,  the  U.S.  NASDAQ  Stock  Market  and  NASDAQ 
Pharmaceuticals Stocks 

The following graph shows the yearly change in cumulative total stockholder return on NexMed Common 

Stock compared to the cumulative total return on the Nasdaq Stock Market (U.S.) and Nasdaq Pharmaceutical 
Stocks for the past 5 fiscal years (assuming a $100 investment on December 31, 2003 and quarterly reinvestment of 
dividends during the period).   

16 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
COMPARISON OF 5 YEAR CUMULATIVE TOTAL RETURN*
Among NexMed, Inc., The NASDAQ Composite Index
And The NASDAQ Pharmaceutical Index

$160

$140

$120

$100

$80

$60

$40

$20

$0

12/03

12/04

12/05

12/06

12/07

12/08

NexMed, Inc.

NASDAQ Composite

NASDAQ Pharmaceutical

*$100 invested on 12/31/03 in stock & index-including reinvestment of dividends.
Fiscal year ending December 31.

NexMed, Inc.
NASDAQ Composite
NASDAQ Pharmaceutical

12/03

12/04

12/05

12/06

12/07

100.00
100.00
100.00

37.59
110.08
110.22

19.30
112.88
111.87

16.79
126.51
114.89

35.59
138.13
106.37

12/08

3.51
80.47
97.32

Unregistered sales of equity securities and use of proceeds 

None. 

17 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ITEM 6.       

SELECTED FINANCIAL DATA. 

The following selected financial information is qualified by reference to, and should be read in conjunction 

with, the Company’s consolidated financial statements and the notes thereto, and “Management’s Discussion and 
Analysis of Financial Condition and Results of Operations” contained elsewhere herein.   

Income Statement Data 

Revenue 
  Product sales and royalties 
  Licensing and research and 
development fees 
Total Expenses, net 
Net Loss  
Basic and Diluted Loss per Share 
Weighted Average Common Shares        
Outstanding Used for Basic and Diluted 
Loss per Share 

2008 

2007 

2006 

2005 

2004 

$1,891 
$5,955,600 

$4,036 
$1,266,331 

$7,243 
$1,859,684 

$9,702 
$2,389,459 

$9,519 
$349,850 

$(11,128,689) 
$(5,171,198) 
$(0.06) 

$(10,057,595) 
$(8,787,228) 
$(0.11) 

$(9,910,180) 
$(8,043,253) 
$(0.12) 

$(17,841,599) 
$(15,442,438) 
$(0.32) 

$(17,383,017) 
$(17,023,648) 
$(0.39) 

83,684,806 

82,015,909 

66,145,807 

52,528,345 

43,603,546 

Balance Sheet Data 

December 31,  December 31,  December 31,  December 31,  December 31, 

Total Assets 
Total Long Term Liabilities 
Stockholders’ Equity 

2008 

$9,441,783 
$5,625,517 
$2,416,400 

2007 
$10,672,706 
$3,538,051 
$4,804,757 

2006 
$19,933,634 
$1,058,098 
$11,504,475 

2005 
$13,331,943 
$4,122,997 
$640,354 

2004 
$20,272,661 
$6,801,826 
$11,401,285 

We do not have any off-balance sheet arrangements.   

ITEM 7.   

   MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND 

RESULTS OF OPERATIONS. 

General  

We are currently focusing our efforts on new and patented topical pharmaceutical products based on a 
penetration enhancement drug delivery technology known as NexACT®, which may enable an active drug to be 
better absorbed through the skin. 

We have applied the NexACT® technology to a myriad of drug compounds and delivery systems, and are 

in various stages of developing new topical treatments for sexual dysfunction, nail fungus, psoriasis, and other 
dermatological conditions.    

We intend to pursue our research, development, and execute a business strategy with the goal of achieving 

a level of development sufficient to enable us to attract potential strategic partners with resources sufficient to 
further develop and market our proprietary products both domestically and internationally.   

Liquidity, Capital Resources and Financial Condition. 

We have experienced net losses and negative cash flows from operations each year since our inception.  

Through December 31, 2008, we had an accumulated deficit of $139,689,300.  Our operations have principally been 

18 

 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
financed through private placements of equity securities and debt financing.  Funds raised in past periods should not 
be considered an indication of our ability to raise additional funds in any future periods.      

In July 2008, Novartis completed testing for the Phase 3 clinical trials for NM100060.  On August 26, 

2008, we announced that based on First Interpretable Results of  two Phase 3 studies, Novartis had decided not to 
submit an NDA to the FDA at this time.  As a result of this decision, we will not receive a $6 million milestone 
payment for positive Phase 3 results, and a $7 million milestone payment for the filing of the NDA has been 
postponed indefinitely.  

Novartis has confirmed that it intends to complete patient testing in the ongoing comparator study which 

they had initiated in March 2007 in ten European countries.  Over 900 patients with mild to moderate 
onychomycosis are participating in this open-label study, which is designed to assess the safety and tolerability of 
NM100060 (terbinafine 10% topical formulation) versus Loceryl® (amorolfine) 5% nail lacquer, a topical treatment 
for onychomycosis that is approved in Europe. The comparator study is expected to be completed by early 2009 and 
the data will be available in mid-2009.  If the results of the comparator study are positive and the total clinical 
database is deemed to be sufficient for filing, we expect Novartis to begin filing for marketing approval in selected 
European countries while they develop a new plan of action for the U.S. market.  If the results are negative, we 
expect Novartis to terminate the global licensing agreement, which it can do at any time, and the rights to 
NM100060 would revert back to us with no compensation for termination.  

On February 3, 2009, we sold the U.S. rights for Vitaros®  and the specific U.S. patents covering Vitaros®  
to Warner and terminated the licensing agreement.  Under the terms of the purchase agreement, we received gross 
proceeds of $2.5 million as an up-front payment and are eligible to receive an additional payment of $2.5 million if 
and when Warner receives an NDA approval from the FDA.  As such, we are no longer responsible for the 
regulatory approval of Vitaros®   and will no longer be eligible to receive royalties in the future based upon the level 
of sales achieved by Warner.  Warner will, however, pay us a total of $350,000 for the manufacturing equipment for 
Vitaros®.  While it is our understanding that Warner is currently moving forward in pursuing NDA approval for 
Vitaros® they are not obligated by the purchase agreement to continue with the development of Vitaros® or obtain 
approval of Vitaros® from the FDA.   

Our current cash reserves of approximately $4.5 million as of the date of this report which includes the $2.5 

million received from Warner on February 3, 2009, should provide us with sufficient cash to fund our operations 
into the first quarter of 2010.  This projection is based on the restructuring plan we implemented in December 2008 
whereby we have reduced our current monthly operating expenditures to $350,000 and plan to further reduce these 
expenditures to approximately $300,000 per month by the second quarter of 2009.  In addition, as part of our 
restructuring plan, we are discussing with Pii the opportunity to co-develop our early stage products which will 
enable us to further reduce our monthly overhead expenses and allow us to sell our facility and redundant 
equipment. We have also initiated efforts to sell the facility housing our corporate office, research and development 
laboratories and manufacturing plant located in East Windsor, New Jersey.  If we can successfully sell our facility 
and repay the existing mortgage, we should be able to reduce our monthly operating expenditures to approximately 
$200,000 per month.  However, there is no assurance that we will be able to sell our facility at an acceptable price or 
otherwise successfully complete our restructuring plan.  

As a result of our losses to date, expected losses in the future, limited capital resources and accumulated 

deficit, our independent registered public accounting firm has concluded that there is substantial doubt as to our 
ability to continue as a going concern for a reasonable period of time, and have modified their report in the form of 
an explanatory paragraph describing the events that have given rise to this uncertainty. These factors may make it 
more difficult for us to obtain additional funding to meet our obligations.  Our continuation is based on our ability to 
generate or obtain sufficient cash to meet our obligations on a timely basis and ultimately to attain profitable 
operations.   We anticipate that we will continue to incur significant losses at least until successful 
commercialization of one or more of our products.  There can be no assurance that we can operate profitably in the 
future. 

At December 31, 2008 we had cash and cash equivalents and short term investments of approximately $2.8 

million as compared to $3.5 million at December 31, 2007.   Our net decrease in cash in 2008 is the result of our 

19 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
average fixed monthly overhead costs of approximately $525,000 per month, in addition to approximately $600,000 
for 2007 bonuses which were paid to employees in March 2008 and $60,000 in severance paid as part of our 
restructuring program implemented in December 2008.  Additionally, we spent approximately $690,000 in direct 
costs to support our NDA and NDS filings for Vitaros®, $300,000 for a cancellation fee as discussed in Note 15 of 
the Consolidated Financial Statements,  $96,000 in direct expenses on our psoriasis project, $161,000 for legal fees 
in connection with a patent lawsuit in which we are the plaintiff suing for patent infringement on our herpes 
treatment medical device, and approximately $106,000 in closing costs on June 30, 2008 as well as a $1 million 
principal repayment on December 31, 2008 related to the convertible notes closed on June 30 as discussed in Note 6 
of the Consolidated Financial Statements.  This cash usage in 2008 was mostly offset by the receipt of $5 million in 
milestone payments from Novartis as discussed in Note 3 of the Consolidated Financial Statements and the net 
proceeds of approximately $2.6 million received upon the issuance of the convertible notes on June 30, 2008 as 
discussed in Note 6 of the Consolidated Financial Statements.   Additionally, we received approximately $938,000 
from the sale of our New Jersey tax credits pursuant to the Technology Tax Certificate Transfer Program as 
discussed in Note 14 of the Consolidated Financial Statements. 

At December 31, 2008, we had $1,029,486 in accounts payable and accrued expenses as compared to 

$621,668 at December 31, 2007.  The increase is attributable to approximately $592,000 accrued and expensed at 
December 31, 2008 for a cancellation fee related to the cancellation of a clinical research agreement for a one-year 
open-label study, as discussed in Note 15 of the Consolidated Financial Statements. 

At December 31, 2008, we had $296,135 in payroll related liabilities as compared to $693,774 at December 

31, 2007. The decrease is attributable to the payment of 2007 bonuses in March 2008. Our bonuses were accrued 
and expensed in 2007 but were not paid until the first quarter of 2008.  There were no bonuses accrued or paid in 
2008. 

At December 31, 2008, we had convertible notes of $4,690,000.  As discussed in Note 6 of the 

Consolidated Financial Statements we issued $5,750,000 of the convertible notes on June 30, 2008 and repaid 
$1,060,000 during 2008. 

At December 31, 2007, we had a note payable of $2,538,705.  The note was paid in cash on June 30, 2008 
with the proceeds received from the convertible notes discussed above.  Therefore, at December 31, 2008, there is 
no remaining balance due to the holder of the note. 

For the year ended December 31, 2008 we incurred loss on disposal of fixed assets (included in general and 

administrative expenses in our consolidated statement of operations) of $904,902 as compared to $10,121 in 2007.  
The significant increase in the loss on disposal of fixed assets resulted from an impairment charge of approximately 
$884,000 to reduce the carrying amount of our land and building to reflect the current commercial real estate market 
as we have initiated efforts to sell this facility.  Since 2000, we have spent approximately $9.4 million in total for the 
land, building, manufacturing and lab equipment, related to our East Windsor facility which we are currently 
occupying. 

  The following table summarizes our contractual obligations and the periods in which payments are due as 

of December 31, 2008: 

20 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Contractual Obligations
 Long-term debt *
 Purchase obligations **
 Other long-term liabilities***

Total
$5,510,750
592,000
1,228,800

Less than
1 year
$328,300
592,000
109,900

1 - 3
years
$5,182,450
0
329,700

3 - 5
years

$0
0
329,700

More than
5 years

$0
0
459,500

     Total

$7,331,550 $1,030,200

$5,512,150

$329,700

$459,500

* Long-term debt consists of a convertible note secured by a mortgage totaling $4.69 million plus all related interest.    
** Purchase obligations consist of a penalty fee for a clinical research agreement that was cancelled on September 30, 2008. 
    The penalty for our cancellation of this $4,182,700 agreement was approximately $892,000.
    $300,000 was paid on December 31, 2008 with the remaining $592,000 due in two installments on March 31, and June 30, 2009.
*** Represents payments to be made according to a deferred compensation agreement.  The present value of these payments  
       is recorded on the balance sheet under deferred compensation in the amount of $1,009,762.

Off-Balance Sheet Arrangements 

We do not have any off-balance sheet arrangements. 

Critical Accounting Estimates  

Our discussion and analysis of our financial condition and results of operations is based upon our 

consolidated financial statements, which have been prepared in accordance with accounting principles generally 
accepted in the United States of America.  Note 2 in the Notes to the Consolidated Financial Statements, includes a 
summary of the significant accounting policies and methods used in the preparation of our Consolidated Financial 
Statements.   The preparation of these financial statements requires our management to make estimates and 
assumptions that affect the reported amounts of assets, liabilities, revenues and expenses, and related disclosure of 
contingent assets and liabilities.  Our accounting policies affect our more significant judgments and estimates used 
in the preparation of our financial statements.  Actual results could differ from these estimates.   The following is a 
brief description of the more significant accounting policies and related estimate methods that we follow: 

Income Taxes – In preparing our financial statements, we make estimates of our current tax exposure and 

temporary differences resulting from timing differences for reporting items for book and tax purposes.  We 
recognize deferred taxes by the asset and liability method of accounting for income taxes.  Under the asset and 
liability method, deferred income taxes are recognized for differences between the financial statement and tax bases 
of assets and liabilities at enacted statutory tax rates in effect for the years in which the differences are expected to 
reverse.  The effect on deferred taxes of a change in tax rates is recognized in income in the period that includes the 
enactment date.  In addition, valuation allowances are established when necessary to reduce deferred tax assets to 
the amounts expected to be realized.   

Critical Estimate:  In consideration of our accumulated losses and lack of historical ability to generate 

taxable income to utilize our deferred tax assets, we have estimated that we will not be able to realize any benefit 
from our temporary differences and have recorded a full valuation allowance.  If we become profitable in the future 
at levels which cause management to conclude that it is more likely than not that we will realize all or a portion of 
the net operating loss carry-forward, we would immediately record the estimated net realized value of the deferred 
tax asset at that time and would then provide for income taxes at a rate equal to our combined federal and state 
effective rates, which would be approximately 40% under current tax laws.  Subsequent revisions to the estimated 
net realizable value of the deferred tax asset could cause our provision for income taxes to vary significantly from 
period to period. 

21 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Long-lived assets -- We review for the impairment of long-lived assets whenever events or circumstances 

indicate that the carrying amount of an asset may not be recoverable.  An impairment loss would be recognized 
when estimated undiscounted future cash flows expected to result from the use of the asset and its eventual 
disposition are less than its carrying amount.  If such assets are considered impaired, the amount of the impairment 
loss recognized is measured as the amount by which the carrying value of the asset exceeds the fair value of the 
asset, fair value being determined based upon discounted cash flows or appraised values, depending on the nature of 
the asset.   

Critical Estimate: We have initiated efforts to sell the facility housing our corporate office, research and 

development laboratories and manufacturing plant located in East Windsor, New Jersey.  We have performed a 
review for impairment of our facility based on discussions with our real estate agent regarding the likely selling 
price of our facility and the commercial real estate market in general.  Accordingly, in 2008 we have taken a write-
down of approximately $884,000 to the carrying value of the facility to approximate the current market value.  
Overestimating the potential selling price of our facility in a planned sale may lead to overstating the carrying value 
of the manufacturing facility by not identifying an impairment loss.    

Revenue recognition -- Revenues from product sales are recognized upon delivery of products to 
customers, less allowances for returns and discounts.   Royalty revenue is recognized upon the sale of the related 
products as reported to us by our distribution partner, provided the royalty amounts are fixed or determinable and the 
amounts are considered collectible.  Revenues earned under license and research and development contracts are 
recognized in accordance with the cost-to-cost method outlined in Staff Accounting Bulletin No. 101, as amended, 
whereby the extent of progress toward completion is measured on the cost-to-cost basis; however, revenue 
recognized at any point will not exceed the cash received.  If the current estimates of total contract revenue and 
contract cost indicate a loss, a provision for the entire loss on the contract would be made.  All costs related to these 
agreements are expensed as incurred and classified within “Research and development” expenses in the 
Consolidated Statements of Operations and Comprehensive Loss. Research and development expenses include costs 
directly attributable to the conduct of our research and development, including salaries, payroll taxes, employee 
benefits, materials, supplies, depreciation on and maintenance of research equipment, costs related to research and 
development fee agreements, the cost of services provided by outside contractors, including services related to our 
clinical trials, clinical trial expenses, the full cost of manufacturing drugs for use in research, pre-clinical and clinical 
development, and the allocable portion of facility costs. 

Also, licensing agreements typically include several elements of revenue, such as up-front payments, 

milestones, royalties upon sales of product, and the delivery of product and/or research services to the licensor. We 
follow the accounting guidance of SEC Staff Accounting Bulletin No. 104 (which superseded SEC Staff Accounting 
Bulletin No. 101), and  EITF No. 91-6 and EITF No. 00-21 (which became effective for contracts entered into after 
June 2003). Non-refundable license fees received upon execution of license agreements where we have continuing 
involvement are deferred and recognized as revenue over the estimated performance period of the agreement. This 
requires management to estimate the expected term of the agreement or, if applicable, the estimated life of its 
licensed patents.  

In addition, EITF No. 00-21 requires a company to evaluate its arrangements under which it will perform 

multiple revenue-generating activities. For example, a license agreement with a pharmaceutical company may 
involve a license, research and development activities and/or contract manufacturing. Management is required to 
determine if the separate components of the agreement have value on a standalone basis and qualify as separate units 
of accounting, whereby consideration is allocated based upon their relative “fair values” or, if not, the consideration 
should be allocated based upon the “residual method.” Accordingly, up-front and development stage milestone 
payments are and will be deferred and recognized as revenue over the performance period of such license 
agreement. 

Critical Estimate:  In calculating the progress made toward completion of a research contract or licensing 

agreement, we must compare costs incurred to date to the total estimated cost of the project and/or estimate the 
performance period.  We estimate the cost and/or performance period of any given project based on our past 
experience in product development as well as the past experience of our research staff in their areas of expertise.  
Underestimating the total cost and/or performance period of a research contract or licensing agreement may cause us 

22 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
to accelerate the revenue recognized under such contract.  Conversely, overestimating the cost may cause us to delay 
revenue recognized.   

Stock based compensation - In preparing our financial statements, we must calculate the value of stock 
options issued to employees, non-employee contractors and warrants issued to investors.  The fair value of each 
option and warrant is estimated on the date of grant using the Black-Scholes option-pricing model.  The Black-
Scholes option-pricing model is a generally accepted method of estimating the value of stock options and warrants. 

Critical Estimate:  The Black-Scholes option pricing model requires us to estimate the Company’s 
dividend yield rate, expected volatility and risk free interest rate over the life of the option.  Inaccurately estimating 
any one of these factors may cause the value of the option to be under or over estimated.  See Note 2 of the 
Consolidated Financial Statements for the current estimates used in the Black-Scholes pricing model.  We adopted 
the provisions of SFAS 123R commencing January 1, 2006. 

Comparison of Results of Operations between the Years Ended December 31, 2008 and 2007  

Revenues. We recorded revenues of  $5,957,491 during 2008 as compared to $1,270,367 during 2007.  The 
increase in revenue in 2008 is primarily attributable to the milestone payments received in 2008 from Novartis under 
the licensing agreement for NM100060. As discussed in Note 3 to the Consolidated Financial Statements, we 
received $1.5 million from Novartis in March 2008 and another $3.5 million in October 2008.  These milestones 
were recognized as revenue during 2008.  

Research and Development Expenses. Our research and development expenses increased from $5,022,671 

in 2007 to $5,410,513 in 2008.    Research and development expenses in the third quarter of 2008 increased 
primarily due to the expense of approximately $892,000 for a cancellation fee related to the cancellation of a 
clinical research agreement for a one-year open-label study for Vitaros® as discussed in Note 15 of the 
Consolidated Financial Statements.  This increase was partially offset by reduced spending in 2008 on our 
development programs including approximately $1.2 million attributable to Vitaros®, as compared to 
approximately $2 million for Vitaros® during 2007. We have continued to spend modestly on the early stage 
development of our topical treatment for psoriasis.  During 2008 we initiated and have spent approximately 
$341,000 on the psoriasis project.  We plan to spend considerably less on research and development in 2009 as we 
actively seek co-development partners for our early stage products under development, including our topical 
treatment for psoriasis.   

 General and Administrative Expenses.  Our general and administrative expenses have increased from 
$5,634,479 in 2007 to $5,720,832 in 2008.   The increase is due to a loss on disposal of fixed assets in 2008 of 
$904,902 as compared to $10,121 in 2007.  The significant increase in the loss on disposal of fixed assets resulted 
from an impairment charge of approximately $884,000 to reduce the carrying amount of our land and building to 
reflect the current commercial real estate market as we have initiated efforts to sell this facility.   The increase in loss 
on disposal of fixed assets was partially offset by a decrease in salary expense of approximately $180,000 as a result 
of no bonuses accrued or paid in 2008 and a reduction in consulting fees of approximately $239,000, as our Chief 
Operating Officer hired in late 2007 and Chief Executive Officer appointed in June 2007 have taken over most of 
the responsibilities handled by consultants in 2007. We also reduced the cost of printing and designing our annual 
report by approximately $63,000 in 2008.  Additionally we had a one-time expense of approximately $257,000 in 
2007 for New Jersey State sales tax paid as a result of a sales tax audit covering the period from 2000 to 2007.   

Interest  Expense.  We recognized $1,006,794 and $481,862 in interest expense in 2008 and 2007 
respectively.  The increase is primarily due to the interest on the $5,750,000 principal amount of convertible notes 
issued on June 30, 2008 and the amortization of debt issue costs for warrants issued in connection with a line of 
credit obtained in May 2008 as discussed in Note 8 to the Consolidated Financial Statements compared to interest 
expense on lesser debt of $2,000,000 in 2007.   

Net Loss.  The net loss was $5,171,198 or $0.06 per share and $8,787,228 or $0.11 per share in 2008 and 
2007, respectively.  The decrease is primarily attributable to the significant increase in revenues attributable to the 
milestones received in 2008 from Novartis under the licensing agreement for NM100060.  As discussed in Note 3 to 

23 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
the Consolidated Financial Statements, we received $1.5 million from Novartis in March 2008 and another $3.5 
million in October 2008.  These milestones were recognized as revenue during 2008.  

Comparison of Results of Operations between the Years Ended December 31, 2007 and 2006  

Revenues. We recorded revenues of  $1,270,367 during 2007 as compared to $1,866,927 during 2006.  The 

decrease in revenue in 2007 is primarily attributable to the method used to recognize revenue from the $4 million 
up-front payment received in 2005 from Novartis under the licensing agreement for NM100060. As discussed in 
Note 3 to the Consolidated Financial Statements, the Novartis agreement was amended in February 2007 such that 
beginning with the first quarter of 2007 we are recognizing the initial up-front payment and preclinical 
reimbursement revenue from this agreement based on a straight-line basis over the 18 month period ended June 30, 
2008 rather than the cost-to-cost method over the 32-month period estimated to complete the remaining preclinical 
studies for NM100060. Accordingly, the Company recognized significantly more revenue in the first quarter of 2006 
because the high costs to initiate the preclinical studies in 2005 and early 2006 resulted in a larger portion of revenue 
recognized under the cost-to-cost method in 2006.  This decrease in revenue is partially offset by the $111,000 in 
revenue recognized in 2007 attributable to the up-front payment received in November 2007 from Warner as 
discussed in Note 3 of the Consolidated Financial Statements.  

Research and Development Expenses. Our research and development expenses decreased from $5,425,137 

in 2006 to $5,022,671 in 2007.    Research and development expenses in 2007 included approximately $2 million 
attributable to Vitaros®  and the balance attributable to other NexACT® technology based products and indirect 
overhead related to research and development, as compared to approximately $940,000 for NM100060 and 
$997,000 for Vitaros®  during 2006.  The majority of our expenses in 2007 were related to the filing of the NDA 
and NDS for Vitaros®  in 2007.  We no longer have research and development expenses related to NM100060, as 
we are no longer obligated to complete the remaining preclinical studies for NM100060.   Novartis has taken over 
all responsibilities related to the remaining preclinical studies whereas in 2006, we incurred the preclinical study 
costs and were reimbursed by Novartis.   

 General and Administrative Expenses.  Our general and administrative expenses have increased from 

$5,570,765 in 2006 to $5,634,479 in 2007.   The modest increase in 2007 is primarily due to New Jersey State sales 
tax paid of approximately $257,000 as a result of a sales tax audit covering the period from 2000 to 2007, 
approximately $175,000 in consulting fees for business development and market research activities related to 
identifying potential commercial partners for Vitaros®  and an increase of approximately $300,000 in legal fees 
related to the national filings of patent applications for Vitaros®  as well as legal fees in connection with a patent 
lawsuit in which we are the plaintiff suing for patent infringement of our herpes treatment medical device.   In 2006 
we recorded a loss on disposal of equipment of approximately $473,000 as a result of the consolidation of our 
operations in that year. 

Interest  Expense.  We recognized $481,862 and $380,860 in interest expense in 2007 and 2006 
respectively.  The increase is primarily due to the $3 million mortgage note executed in October 2007 as discussed 
in Note 7 of the Consolidated Financial Statements whereby we began amortizing $51,255 of the note discount in 
2007.  Additionally, as discussed in Note 7 of the Consolidated Financial Statements, in 2007 we incurred ten 
months of interest expense on the $2 million Note that was repaid in October 2007 as compared to only one month 
of interest in 2006.   

Other income.   Other income was $0 in 2007 as compared to $627,455 in 2006.  The 2006 other income 

consisted of a one-time payment received when Schering elected to terminate the supply and distribution agreement 
for Vitaros® without cause.  Pursuant to the agreement, Schering was obligated to pay a termination fee of 500,000 
Euros or $627,455.   

Net Loss.  The net loss was $8,787,228 and  $8,043,253 in 2007 and 2006, respectively.  The increase is 
primarily attributable to the decrease in revenues primarily attributable to the method used to recognize revenue 
from the $4 million up-front payment received in 2005 from Novartis under the licensing agreement for NM100060. 
As discussed in Note 3 to the Consolidated Financial Statements, the Novartis agreement was amended in February 
2007 such that beginning with the first quarter of 2007 we are recognizing the initial up-front payment and 

24 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
preclinical reimbursement revenue from this agreement based on a straight-line basis over the 18 month period 
ended June 30, 2008 rather than the cost-to-cost method over the 32-month period estimated to complete the 
remaining preclinical studies for NM100060. Accordingly, the Company recognized significantly more revenue in 
2006 as the preclinical studies were initiated because the high costs to initiate the preclinical studies in 2005 and 
early 2006 resulted in a larger portion of revenue recognized under the cost-to-cost method in 2006.   

Net Loss applicable to Common Stock.  The net loss applicable to Common Stock was $8,787,228 or $0.11 

per share as compared to  $8,108,414 or $0.12 per share for 2006.  The increase in net loss applicable to Common 
Stock is primarily attributable to the decrease in revenue as discussed above. 

Quarterly Results 

The following table sets forth selected unaudited quarterly financial information for the years ended 

December 31, 2008 and 2007.  The operating results are not necessarily indicative of results for any future period.  

Total Revenues 
Income (Loss) from 
Operations 
Net Income (Loss) 
Basic & Diluted 
Income (Loss) 
Per Share 

Total Revenues 
Loss from 
Operations 
Net Loss 
Basic & Diluted 
Loss 
Per Share 

For the Three Months Ended 

March 31, 2008 

June 30, 2008 

$951,787 
($1,520,702) 

($1,642,187) 
$(0.02) 

$1,199,612 
($1,090,169) 

($1,628,723) 
$(0.02) 

September 30, 2008  December 31, 2008 
$3,500,149 
$333,808 

$305,943 
($2,896,791)  

($3,040,094)  
$(0.04) 

$1,139,806 
$0.01 

March 31, 2007 

June 30, 2007 

$286,959 

$283,417 

September 30, 2007  December 31, 2007 
$403,601 

$296,390 

($2,023,819) 
($2,039,309) 

($1,975,228) 
($1,991,021) 

($2,007,823) 
($2,026,378) 

($3,379,913) 
($2,730,520) 

$(0.03) 

$(0.02) 

$(0.02) 

$(0.03) 

ITEM 7A. 

QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK. 

We do not hold derivative financial investments, derivative commodity investments, engage in foreign 

currency hedging or other transactions that expose us to material market risk.  The interest rates on our existing debt 
are fixed. 

25 

 
 
 
 
 
 
 
 
 
 
      
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ITEM 8. 

FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA. 

INDEX TO FINANCIAL STATEMENTS 

Report of Independent Registered Public Accounting Firm 2008, 2007 and 2006  

Financial Statements: 

Consolidated Balance Sheets - December 31, 2008 and 2007 

Consolidated Statements of Operations and Comprehensive Loss for the years 
ended December 31, 2008, 2007 and 2006  

Consolidated Statements of Changes in Stockholders' Equity for years ended 
December 31, 2008, 2007 and 2006 

Consolidated Statements of Cash Flows for the years ended December 31, 2008, 
2007 and 2006 

Notes to the Consolidated Financial Statements 

Schedule II – Valuation of Qualifying Accounts 

PAGE 
27 

29 

30 

31 

32 

33 

73 

26 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Report of Independent Registered Public Accounting Firm 

To the Board of Directors 
Stockholders of NexMed, Inc.  

We have audited the accompanying consolidated balance sheets of NexMed, Inc. and subsidiaries as of December 31, 2008 
and  2007,  and  the  related  consolidated  statements  of  operations,  stockholders’  equity  and  cash  flows  for  the  years  ended 
December 31, 2008, 2007 and 2006.  Our audits also include the financial statement schedule included in Item 15.  We also 
have audited NexMed, Inc.’s internal control over financial reporting as of December 31, 2008, based on criteria established 
in  Internal  Control-Integrated  Framework  issued  by  the  Committee  of  Sponsoring  Organizations  of  the  Treadway 
Commission  (COSO).    NexMed,  Inc.’s  management  is  responsible  for  these  financial  statements  and  financial  statement 
schedule,  for  maintaining  effective  internal  control  over  financial  reporting,  and  for  its  assessment  of  the  effectiveness  of 
internal  control  over  financial  reporting,  included  in  the  accompanying  Management’s  Report  on  Internal  Control  over 
Financial  Reporting.    Our  responsibility  is  to  express  an  opinion  on  these  financial  statements  and  financial  statement 
schedule and an opinion on the Company’s internal control over financial reporting based on our audits. 

We  conducted  our  audits  in  accordance  with  the  standards  of  the  Public  Company  Accounting  Oversight  Board  (United 
States).    Those  standards  require  that  we  plan  and  perform  the  audits  to  obtain  reasonable  assurance  about  whether  the 
financial  statements  are  free  of  material  misstatement  and  whether  effective  internal  control  over  financial  reporting  was 
maintained  in  all  material  respects.    Our  audits  of  the  financial  statements  included  examining,  on  a  test  basis,  evidence 
supporting the amounts and disclosures in the financial statements, assessing the accounting principles used and significant 
estimates  made  by  management,  and  evaluating  the  overall  financial  statement  presentation.    Our  audit  of  internal  control 
over financial reporting  included  obtaining an understanding  of internal control over  financial reporting,  assessing  the risk 
that a material weakness exists, and testing and evaluating the design and operating effectiveness of internal control based on 
the  assessed  risk.    Our  audits  also  included  performing  such  other  procedures  as  we  considered  necessary  in  the 
circumstances.  We believe that our audits provide a reasonable basis for our opinions. 

A company’s internal control over financial reporting is a process designed to provide reasonable assurance regarding the 
reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally 
accepted accounting principles.  A company’s internal control over financial reporting includes those policies and procedures 
that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and 
dispositions of the assets of the company; (2) provide reasonable assurance that transactions are recorded as necessary to 
permit preparation of financial statements in accordance with generally accepted accounting principles, and that receipts and 
expenditures of the company are being made only in accordance with authorizations of management and directors of the 
company; and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or 
disposition of the company’s assets that could have a material effect on the financial statements. 

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements.  Also, 
projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate 
because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate. 

In  our  opinion,  the  financial  statements  and  financial  statement  schedule  referred  to  above  present  fairly,  in  all  material 
respects, the financial position of NexMed, Inc. and subsidiaries as of December 31, 2008 and 2007, and the results of its 
operations  and  its  cash  flows  for  the  years  ended  December  31,  2008,  2007  and  2006  in  conformity  with  accounting 
principles  generally  accepted  in  the  United  States  of  America.    Also  in  our  opinion,  NexMed,  Inc.  and  subsidiaries 
maintained,  in  all  material  respects,  effective  internal  control  over  financial  reporting  as  of  December  31,  2008,  based  on 
criteria  established  in  Internal  Control-Internal  Framework  issued  by  the  Committee  of  Sponsoring  Organizations  of  the 
Treadway Commission (COSO). 

The accompanying financial statements have been prepared assuming that the Company will continue as a going concern. As 
discussed in Note 1 to the financial statements, the Company has suffered recurring losses and negative cash flows from 
operations and expects to incur future losses that raise substantial doubt about its ability to continue as a going concern.  

27 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Management’s plans in regard to these matters are also described in Note 1.  The accompanying consolidated financial 
statements do not include any adjustments that might result from the outcome of this uncertainty. 

/s/ Amper, Politziner & Mattia, LLP 

March 16, 2009 
Edison, New Jersey 

28 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
NexMed, Inc. 
Consolidated Balance Sheets 

Assets
Current assets

December 31,

2008

2007

Cash and cash equivalents
Short term investments
Debt issuance cost, net of accumulated amortization of $43,283 and $7,565 
Prepaid expenses and other current assets

$       

2,862,960

-
30,368
83,761

$       

2,735,940
750,000
68,081
127,659

Total current assets

2,977,089

3,681,680

Fixed assets, net
Debt issuance cost, net of accumulated amortization of $86,607 and $3,782

5,519,652
60,771

6,956,986
34,040

Total assets

$      

8,557,512

$    

10,672,706

Liabilities and Stockholders' Equity
Current liabilities

Accounts payable and accrued expenses
Payroll related liabilities
Deferred revenue
Deferred compensation - current portion

Total current liabilities

Long term liabilities

Convertible notes payable
Note payable, net of debt discount of $461,295
Deferred compensation

Total liabilities

Commitments and contingincies (Note 15) 

$       

1,029,486
296,135
-
74,245

$          

621,668
693,774
953,528
60,929

1,399,866

2,329,899

4,690,000

-
935,517

-

2,538,705
999,345

7,025,383

5,867,949

Stockholders' equity:

Common stock, $.001 par value, 120,000,000 shares authorized,

84,350,361 and 83,063,002 shares issued and outstanding, respectively

Additional paid-in capital
Accumulated deficit

84,352
141,137,077
(139,689,300)

83,065
139,239,794
(134,518,102)

Total stockholders' equity

1,532,129

4,804,757

Total liabilities and stockholders' equity

$      

8,557,512

$    

10,672,706

The accompanying notes are an integral part of these consolidated financial statements. 

29 

 
 
 
 
 
 
 
 
 
 
                   
            
              
              
              
            
         
         
         
         
              
              
            
            
                   
            
              
              
         
         
         
                   
                   
         
            
            
         
         
              
              
     
     
   
   
         
         
 
 
 
 
NexMed, Inc. 
Consolidated Statements of Operations 

For the Year Ended
December 31,
2007

2006

2008

Revenues, principally license fee revenue

$5,957,491

$1,270,367

$1,866,927

Costs and expenses

Research and development
General and administrative

5,410,513
5,720,832

5,022,671
5,634,479

5,425,137
5,570,765

Total costs and expenses

11,131,345

10,657,150

10,995,902

Loss from operations

Other income (expense)

Interest income
Other income
Interest expense

Total other income (expense)

(5,173,854)

(9,386,783)

(9,128,975)

71,793
-

(1,006,794)
(935,001)

275,508
-
(481,862)
(206,354)

271,730
627,455
(380,860)
518,325

Loss before benefit from income taxes

(6,108,855)

(9,593,137)

(8,610,650)

Benefit from income taxes

937,657

805,909

567,397

Net loss

(5,171,198)

(8,787,228)

(8,043,253)

Deemed dividend to preferred shareholders
  from beneficial conversion feature
Preferred dividend

-
-

-
-

(49,897)
(15,264)

Net loss applicable to common stock

($5,171,198)

($8,787,228)

($8,108,414)

Basic and diluted loss per share

$                   

(.06)

$                  

(.11)

$                      

(.12)

Weighted average common shares outstanding

used for basic and diluted loss per share

83,684,806

82,015,909

66,145,807

The accompanying notes are an integral part of these consolidated financial statements. 

30 

 
 
 
 
 
 
 
 
 
                
             
                 
                      
                     
                 
                      
                     
                 
                      
                     
                 
 
       
      
            
NexMed, Inc. 
Consolidated Statements of Changes in Stockholders’ Equity 

Balance at January  1, 2 006

5 5,6 99 ,46 7

$ 55 ,70 0

$11 8,2 81 ,87 1

( $11 7,6 87, 621 )

( $9, 596 )

$6 40 ,354

C ommo n
Sto ck
(Shares)

Co mmo n
Sto ck
(Amo unt)

Additional
Pa id- In
Capita l

Accumula ted
Deficit

Fo reign
Currency
t ra nslat io n

Tot al
Sto ckho lders'
Equity

Issuance o f com mo n stock

up on exercise of  stock o ptio ns and warrants, net

Issuance o f com pensator y op tions to  em ployees and  consultants
Issuance o f com mo n stock in paym en t o f in terest o n conv ertib le no tes
Issuance o f com pensator y sto ck  to  th e b oard  of d ir ecto rs
Issuance o f com mo n stock

fro m p rivate placement, net o f o ffer ing  co sts

Issuance o f com mo n stock up on con versio n

2 08 ,09 5
-
3 92 ,46 7
1 97 ,26 4

20 8
-
39 3
19 7

97 ,10 8
1,2 14 ,40 3
3 03 ,77 4
1 43 ,80 4

2 2,6 64 ,19 1

22 ,66 4

1 6,3 18 ,99 3

of  preferred stock, includ in g dividends p aid in stock

1,1 24 ,42 1

1 ,12 5

8 73 ,87 5

-
-
-
-

-

-

-
-
-
-

-

-

Amo rtizatio n o f beneficial co nversion f eatu re,  disco unt an d issuan ce 

costs r elated  to p ref err ed  sto ck

Discou nt  on N ote p ayable for  issuance o f warrants
Net loss

Balance at Decem ber 3 1, 2 00 6

Issuance o f com mo n stock

up on exercise of  stock o ptio ns and warrants, net

Issuance o f com pensator y op tions to  em ployees and  consultants
Issuance o f com pensator y sto ck  to  employees an d con su ltan ts
Issuance o f com mo n stock in paym en t o f in terest o n no tes
Issuance o f com pensator y sto ck  to  th e b oard  of d ir ecto rs
Net o fferin g costs f rom  issu ance of  co mm on  stock
Discou nt  on N ote p ayable for  issuance o f warrants
Realized g ain o n fo reign  cur rency  ex chang e
Net loss

-
8 0,2 85 ,90 5

-
$80 ,28 7

(2 07 ,17 0)
1 38 ,00 0
-
$13 7,1 64 ,65 8

-
-
( 8,0 43, 253 )
( $12 5,7 30, 874 )

-
-
-
( $9, 596 )

1,7 17 ,94 3
-
6 09 ,00 0
1 45 ,61 4
3 04 ,54 0
-
-

-

1 ,71 8
-
60 9
14 6
30 5
-
-

-

2 19 ,17 5
7 76 ,83 5
89 ,39 1
1 90 ,60 2
2 88 ,69 3
(2 ,11 0)
5 12 ,55 0

-
-
-
-
-
-
-

-

( 8,7 87, 228 )

Balance at Decem ber 3 1, 2 00 7

8 3,0 63 ,00 2

$83 ,06 5

$13 9,2 39 ,79 4

( $13 4,5 18, 102 )

Issuance o f com mo n stock

up on exercise of  stock o ptio ns and warrants

Issuance o f com pensator y op tions to  em ployees and  consultants
Issuance o f com pensator y sto ck  to  employees an d con su ltan ts
Issuance o f com pensator y sto ck  to  th e b oard  of d ir ecto rs
Discou nt  on N ote p ayable for  issuance o f warrants
Net loss

5 26 ,90 9
-
3 82 ,50 0
3 77 ,95 0
-
-

52 7
-
38 2
37 8
-
-

4 59 ,22 1
1 38 ,51 1
7 04 ,35 0
4 80 ,45 1
1 14 ,75 0
-

-
-
-
-
-
( 5,1 71, 198 )

Balance at Decem ber 3 1, 2 00 8

8 4,3 50 ,36 1

$84 ,35 2

$1 41, 137 ,07 7

( $13 9,6 89, 300 )

-
-
-
-
-
-
-
9, 596
-

-

-
-
-
-
-
-

-

97 ,316
1,2 14 ,403
3 04 ,167
1 44 ,001

1 6,3 41 ,657

8 75 ,000

(2 07 ,170 )
1 38 ,000
( 8,0 43 ,253 )
$ 11, 504 ,47 5

2 20 ,893
7 76 ,835
90 ,000
1 90 ,748
2 88 ,998
(2 ,110 )
5 12 ,550
9 ,596
( 8,7 87 ,228 )

$4, 804 ,75 7

4 59 ,748
1 38 ,511
7 04 ,732
4 80 ,829
1 14 ,750
( 5,1 71 ,198 )

$1, 532 ,12 9

The accompanying notes are an integral part of these consolidated financial statements. 

31 

 
 
 
 
 
 
 
 
 
 
NexMed, Inc. 
Consolidated Statements of Cash Flows 

Cash flows from operating activities

Net loss
Adjustments to reconcile net loss to net cash

used in operating activities
Depreciation and amortization
Non-cash interest, amortization of debt discount and
  deferred financing costs
Non-cash compensation expense
Net gain on foreign currency exchange
Impairment charge and loss on disposal of property and equipment

Changes in assets and liabilities

Decrease (increase) in other receivable
Decrease in prepaid expense and other assets
(Decrease) increase in deferred revenue
(Decrease) increase in payroll related liabilities
(Decrease) increase in deferred compensation
Increase (decrease) in accounts payable and accrued expenses

Net cash used in operating activities

Cash flows from investing activities

Proceeds from sale of fixed assets
Capital expenditures
Purchases of short term investments
Proceeds from sale of short term investments

Net cash provided by (used in) investing activities

Cash flows from financing activities

Issuance of common stock, net of offering costs
Proceeds from exercise of stock options and warrants
Issuance of convertible notes payable, net of debt issue costs
Issuance of notes payable, net of debt issue costs
Repayment of notes payable
Repayment of convertible notes payable
Principal payments on capital lease obligations

For the Year Ended
December 31,
2007

2008

2006

$    

(5,171,198)

$    

(8,787,228)

$    

(8,043,253)

486,420

621,869

842,087

693,316
1,324,072
-
904,902

43,898
(953,528)
(397,639)
(50,512)
407,818

408,538
1,155,832
9,596
10,121

183,700
37,239
(740,389)
537,207
(58,036)
33,918

328,050
1,358,403
-
473,312

(183,700)
791,477
(1,091,884)
156,567
(59,889)
(1,238,184)

(2,712,451)

(6,587,633)

(6,667,014)

75,000
(28,988)
-
750,000

796,012

-
(100,875)
(3,000,000)
3,250,000

178,769
(76,553)
(6,000,000)
5,500,000

149,125

(397,784)

-
459,748
5,643,711
-
(4,000,000)
(60,000)
-

(2,110)
220,893

16,341,657
97,316

2,886,532
(2,000,000)
(3,000,000)
-

1,975,000

(3,000,000)
(233,823)

Net cash provided by (used in) financing activities

2,043,459

(1,894,685)

15,180,150

Net increase (decrease) in cash and cash equivalents

127,020

(8,333,193)

8,115,352

Cash and cash equivalents

Beginning of year

End of year

Cash paid for interest

2,735,940

11,069,133

2,953,781

$      

2,862,960

$     

2,735,940

$   

11,069,133

$      

324,314

$       

119,307

$        

91,912

Supplemental disclosure of non-cash investing and financing activities:

Payment of interest in common stock
Amortization of debt discount 
Conversion of preferred stock to common stock
Preferred stock dividend paid in common stock

-
461,295
-
-

190,748
178,640
-
-

304,167
10,615
859,736
15,264

The accompanying notes are an integral part of these consolidated financial statements. 

32 

 
 
 
 
 
 
 
 
                 
     
     
         
      
      
         
         
        
NexMed, Inc. 
Notes to Consolidated Financial Statements 

1.  Organization and Basis of Presentation 

The Company was incorporated in Nevada in 1987.  In January 1994, the Company began research and 
development of a device for the treatment of herpes simplex.  The Company, since 1995, has conducted research 
and development both domestically and abroad on proprietary pharmaceutical products, with the goal of growing 
through acquisition and development of pharmaceutical products and technology. 

The accompanying consolidated financial statements have been prepared on a basis which contemplates the 
realization of assets and the satisfaction of liabilities and commitments in the normal course of business.  The 
Company has an accumulated deficit of $139,689,300 at December 31, 2008 and expects that it will incur 
additional losses in the future completing the research, development and commercialization of its technologies.  
These circumstances raise substantial doubt about the Company's ability to continue as a going concern.  
Management anticipates that the Company will require additional financing, which it is actively pursuing, to fund 
operations, including continued research, development and clinical trials of the Company’s product candidates.  
Although management continues to pursue these plans, there is no assurance that the Company will be successful 
in obtaining financing on terms acceptable to the Company.  If the Company is unable to obtain additional 
financing, operations will need to be discontinued.  The financial statements do not include any adjustments that 
might result from the outcome of this uncertainty. 

2.  Summary of Significant Accounting Principles 

Significant accounting principles followed by the Company in preparing its financial statements are as follows: 

Principles of consolidation 
The consolidated financial statements include the accounts of the Company and its wholly owned subsidiaries.  
All significant intercompany accounts and transactions have been eliminated. 

Cash and cash equivalents 
For purposes of the balance sheets and the statements of cash flows, cash equivalents represent all highly liquid 
investments with an original maturity date of three months or less. 

Short term investments 
A significant amount of our short term investments at December 31, 2007 were comprised of investment grade 
variable rate debt obligations, which are asset-backed and categorized as available-for-sale.  Accordingly, our 
investments in these securities are recorded at cost, which approximates fair value due to their variable interest 
rates, which typically reset every 28 days.  Despite the long-term nature of their contractual maturities, we have 
the ability and intent to liquidate these securities within one year.  As a result of the resetting variable rates, we 
had no cumulative gross unrealized or realized holding gains or losses from these investments.  All income 
generated from these investments was recorded as interest income.  The Company had no such investments at 
December 31, 2008. 

Fair value of financial instruments 
The carrying value of cash and cash equivalents, convertible notes payable, accounts payable and accrued 
expenses and deferred compensation approximates fair value due to the relatively short maturity of these 
instruments. 

Fixed assets 
Property and equipment are stated at cost less accumulated depreciation.  Depreciation of equipment and 
furniture and fixtures is provided on a straight-line basis over the estimated useful lives of the assets, generally 
three to ten years.  Depreciation of buildings is provided on a straight-line basis over the estimated useful life of 
31 years.  Amortization of leasehold improvements is provided on a straight-line basis over the shorter of their 
estimated useful life or the lease term.  The costs of additions and betterments are capitalized, and repairs and 
maintenance costs are charged to operations in the periods incurred. 

33

 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

Long-lived assets 
The Company reviews for the impairment of long-lived assets whenever events or circumstances indicate that the 
carrying amount of an asset may not be recoverable.  An impairment loss would be recognized when estimated 
undiscounted future cash flows expected to result from the use of the asset and its eventual disposition is less than 
its carrying amount.  If such assets are considered impaired, the amount of the impairment loss recognized is 
measured as the amount by which the carrying value of the asset exceeds the fair value of the asset, fair value 
being determined based upon discounted cash flows or appraised values, depending on the nature of the asset.  
The Company recorded an impairment charge of $884,271 in 2008 to reduce the carrying amount of its land and 
building to reflect the current commercial real estate market as the Company has initiated efforts to sell its 
facility.  This charge is recorded within general and administrative expenses on the statement of operations.  No 
such impairment losses have been recorded by the Company during 2007 or 2006. 

Revenue recognition 
Revenues from product sales are recognized upon delivery of products to customers, less allowances for 
estimated returns and discounts.  Royalty revenue is recognized upon the sale of the related products, provided 
the royalty amounts are fixed or determinable and the amounts are considered collectible.  Revenues from 
product sales and royalties are immaterial in 2008, 2007 and 2006. 

Revenues earned under licensing and research and development contracts are recognized in accordance with the 
cost-to-cost method whereby the extent of progress toward completion is measured on the cost-to-cost basis; 
however, revenue recognized at any point will not exceed the cash received.  When the current estimates of total 
contract revenue and contract cost indicate a loss, a provision for the entire loss on the contract is made in the 
period which it becomes probable.  All costs related to these agreements are expensed as incurred and classified 
within “Research and development” expenses in the Consolidated Statements of Operations. 

Also, licensing agreements typically include several elements of revenue, such as up-front payments, milestones, 
royalties upon sales of product, and the delivery of product and/or research services to the licensor. We follow the 
accounting guidance of SEC Staff Accounting Bulletin No. 104 (which superseded SEC Staff Accounting 
Bulletin No. 101) and EITF No. 91-6 and EITF No. 00-21 (which became effective for contracts entered into 
after June 2003). Non-refundable license fees received upon execution of license agreements where we have 
continuing involvement are deferred and recognized as revenue over the estimated performance period of the 
agreement. This requires management to estimate the expected term of the agreement or, if applicable, the 
estimated life of its licensed patents.  

In addition, EITF No. 00-21 requires a company to evaluate its arrangements under which it will perform 
multiple revenue-generating activities. For example, a license agreement with a pharmaceutical company may 
involve a license, research and development activities and/or contract manufacturing. Management is required to 
determine if the separate components of the agreement have value on a standalone basis and qualify as separate 
units of accounting, whereby consideration is allocated based upon their relative “fair values” or, if not, the 
consideration should be allocated based upon the “residual method.” Accordingly, up-front and development 
stage milestone payments will be deferred and recognized as revenue over the performance period of such license 
agreement. 

Research and development 
Research and development costs are expensed as incurred and include the cost of salaries, building costs, utilities, 
allocation of indirect costs, and expenses to third parties who conduct research and development, pursuant to 
development and consulting agreements, on behalf of the Company. 

Income taxes 
Income taxes are accounted for under the asset and liability method.  Deferred income taxes are recorded for 
temporary differences between financial statement carrying amounts and the tax bases of assets and liabilities.  
Deferred tax assets and liabilities reflect the tax rates expected to be in effect for the years in which the 
differences are expected to reverse.  A valuation allowance is provided if it is more likely than not that some or 
all of the deferred tax assets will not be realized. 

34

 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

Loss per common share 
Basic earnings per share is computed by dividing income available to common stockholders by the weighted 
average number of common shares outstanding during the period.  Diluted earnings per share gives effect to all 
dilutive potential common shares outstanding during the period.  The computation of diluted earnings per share 
does not assume conversion, exercise or contingent exercise of securities that would have an antidilutive effect on 
per share amounts. 

At December 31, 2008, 2007 and 2006, outstanding options to purchase 3,368,991, 3,469,841, and 3,663,421 
shares of Common Stock, respectively, with exercise prices ranging from $0.55 to $16.25 have been excluded 
from the computation of diluted loss per share as they are antidilutive.  At December 31, 2008, 2007 and 2006, 
outstanding warrants to purchase 12,118,044, 12,439,954, and 20,125,027 shares of Common Stock, respectively, 
with exercise prices ranging from $0.55 to $4.04 have also been excluded from the computation of diluted loss 
per share as they are antidilutive.  Promissory notes convertible into 2,345,000 shares of Common Stock in 2008 
and 600,000 shares of Common Stock (see Note 6) in 2006 have also been excluded from the computation of 
diluted loss per share, as they are antidilutive.   

Accounting for stock based compensation 

Effective January 1, 2006, the Company adopted the provisions of Statement of Financial Accounting Standards 
No. 123R, “Share-Based Payment”, which establishes the financial accounting and reporting standards for stock-
based compensation plans. SFAS 123R requires the measurement and recognition of compensation expense for 
all stock-based awards made to employees and directors, including employee stock options. Under the provisions 
of SFAS 123R, stock-based compensation cost is measured at the grant date, based on the calculated fair value of 
the award, and is recognized as an expense on a straight-line basis over the requisite service period of the entire 
award (generally the vesting period of the award).  The Company adopted the provisions of SFAS 123R as of 
January 1, 2006 using the modified prospective transition method.   Under this transition method, stock-based 
compensation expense for the year ended December 31, 2006 includes expense for all equity awards granted 
during the year ended December 31, 2006 and prior, but not yet vested as of January 1, 2006, based on the grant 
date fair value estimated in accordance with the original provisions of SFAS No. 123, “Accounting for Stock-
Based Compensation” as amended by SFAS 148, “Accounting for Stock-Based Compensation—Transition and 
Disclosure.” Also in accordance with the modified prospective transition method, prior interim and annual 
periods have not been restated and do not reflect the recognition of stock-based compensation cost under SFAS 
123R.  Since the adoption of SFAS 123R, there have been no changes to the Company’s stock compensation 
plans or modifications to outstanding stock-based awards which would increase the value of any awards 
outstanding. Compensation expense for all stock-based compensation awards granted subsequent to January 1, 
2006 was based on the grant-date fair value determined in accordance with the provisions of SFAS 123R.   

The Company accounts for stock options granted to non-employees on a fair value basis in accordance with 
SFAS No. 123, "Accounting for Stock-Based Compensation," and Emerging Issues Task Force Issue No. 96-18, 
"Accounting for Equity Instruments That Are Issued to Other Than Employees for Acquiring, or in Conjunction 
with Selling, Goods or Services." Any options issued to non-employees are recorded in the consolidated financial 
statements in deferred expenses in stockholders' equity using the fair value method and then amortized to expense 
over the applicable service periods (See Note 9). As a result, the non-cash charge to operations for non-employee 
options with vesting or other performance criteria is valued each reporting period based upon changes in the fair 
value of the Company's Common Stock. 

As a result of adopting SFAS 123R, the Company’s net loss and its non cash compensation expense as shown in 
the Consolidated Statements of Operations for the years ended December 31, 2008, 2007 and 2006 is $1,324,071, 
$1,095,834 and $1,358,403 more, respectively, than if the Company had continued to account for stock-based 
compensation under Accounting Principles Board Opinion No. 25, “Accounting for Stock Issued to Employees” 
and its related interpretations. Basic and diluted net loss per share for the years ended December 31, 2008, 2007 
and 2006 of $(0.05), $(0.11) and $(0.12), respectively, is $0.01, $0.01 and $0.02 more than if the Company had 
not adopted SFAS 123R. 

35

 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

The following table indicates where the total stock-based compensation expense resulting from stock options and 
awards appears in the Statements of Operations: 

Research and development
General and administrative

Total stock-based 
compensation expense 

Year Ended

December 31, 2008
$71,833
1,252,239

December 31, 2007
$111,108
1,044,724

$1,324,072

$1,155,832

The stock-based compensation expense has not been tax-effected due to the recording of a full valuation 
allowance against U.S. net deferred tax assets. 

The fair value of each stock option grant is estimated on the grant date using the Black-Scholes option-pricing 
model with the following assumptions used for the years ended December 31, 2008, 2007 and 2006: 

Dividend yield
Risk-free yields
Expected volatility
Expected option life
Forfeiture rate

0.00%
1.35% - 5.02%
54.38% - 103.51%
1 - 6 years
6.41%

Expected Volatility .The Company uses analysis of historical volatility to compute the expected volatility of its 

stock options.   

Expected Term. The expected term is based on several factors including historical observations of employee 

exercise patterns during the Company’s history and expectations of employee exercise behavior in the future 
giving consideration to the contractual terms of the stock-based awards.   

Risk-Free Interest Rate. The interest rate used in valuing awards is based on the yield at the time of grant of a 

U.S. Treasury security with an equivalent remaining term. 

Dividend Yield. The Company has never paid cash dividends, and does not currently intend to pay cash 

dividends, and thus has assumed a 0% dividend yield. 

Pre-Vesting Forfeitures. Estimates of pre-vesting option forfeitures are based on Company experience. The 

Company will adjust its estimate of forfeitures over the requisite service period based on the extent to which 
actual forfeitures differ, or are expected to differ, from such estimates. Changes in estimated forfeitures will be 
recognized through a cumulative catch-up adjustment in the period of change and will also impact the amount of 
compensation expense to be recognized in future periods. The cumulative effect resulting from initially applying 
the provisions of SFAS 123R to nonvested equity awards was not significant. 

Additional disclosures required under SFAS 123R are presented in Note 9. 

Concentration of credit risk 

From time to time, the Company maintains cash in bank accounts that exceed the FDIC insured limits. The 
Company has not experienced any losses on its cash accounts.  

36

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

Accounting estimates 

The preparation of financial statements in conformity with accounting principles generally accepted in the United 
States requires management to make estimates that affect the reported amounts of assets and liabilities at the date 
of the financial statements and the reported amounts of revenues and expenses during the reporting period.  The 
Company’s most significant estimates relate to the valuation of its long-lived assets, estimated cost to complete 
under its research contracts, and valuation allowances for its deferred tax benefit.  Actual results may differ from 
those estimates. 

Recent accounting pronouncements 

In  February  2007,  the  Financial  Accounting  Standards  Board  (the  “FASB”)  issued  SFAS  No.  159,  “The  Fair 
Value Option for Financial Assets and Financial Liabilities”, including an amendment of FASB No. 115 ("FAS 
159"). The Statement permits companies to choose to measure many financial instruments and certain other items 
at fair value in order to mitigate volatility in reported earnings caused by measuring related assets and liabilities 
differently without having to apply complex hedge accounting provisions. FAS 159 is effective for the Company 
beginning  January  1,  2008.  The  adoption  of  this  standard  has  not  had  a  significant  impact  on  the  Company’s 
consolidated financial position, results of operations or cash flows. 

In  December  2007,  the  FASB  issued  Statement  of  Financial  Accounting  Standard  No. 160,  “Noncontrolling 
Interests  in  Consolidated  Financial  Statements  —  an  amendment  of  ARB  No. 51”  (“FAS  160”).   FAS  160 
establishes accounting and reporting standards for the non-controlling interest in a subsidiary and for the retained 
interest and gain or loss when a subsidiary is deconsolidated. This statement is effective for financial statements 
issued for fiscal years beginning on or after December 15, 2008 with earlier adoption prohibited. The adoption of 
this  standard  is  not  expected  to  have  a  significant  impact  on  the  Company’s  consolidated  financial  position, 
results of operations or cash flows. 

In  December  2007,  the  FASB  issued  SFAS  No.  141R,  "Business  Combinations,"  (“SFAS  141R”)  which 
establishes principles and requirements for how an acquirer recognizes and measures in its financial statements 
the  identifiable  assets  acquired,  the  liabilities  assumed  and  any  non-controlling  interest  in  the  acquiree.  SFAS 
141R also establishes disclosure requirements to enable the evaluation of the nature and financial effects of the 
business combination. SFAS 141R applies prospectively to business combinations for which the acquisition date 
is  on  or  after  the  beginning  of  the  first  annual  reporting  period  beginning  on  or  after  December  15,  2008,  and 
interim periods within those fiscal years. The Company is currently evaluating the impact, if any, of SFAS 141R 
on its operating results and financial position. 

In May 2008, the FASB issued Staff Position No. APB 14-1 “Accounting for Convertible Debt Instruments That 
May Be Settled in Cash Upon Conversion (Including Partial Cash Settlement)” (“FSP APB 14-1”), which 
clarifies the accounting for convertible debt instruments that may be settled in cash (including partial cash 
settlement) upon conversion.  FSP APB 14-1 requires issuers to account separately for the liability and equity 
components of certain convertible debt instruments in a manner that reflects the issuer’s non-convertible debt 
borrowing rate when interest cost is recognized.  FSP APB 14-1 requires retrospective application to the terms of 
the instruments as they existed for all periods presented.  FSB APB 14-1 is effective for the Company as of 
January 1, 2009 and early adoption is prohibited.  The Company is currently evaluating the impact of adopting 
FSP APB 14-1 on its consolidated financial statements as a result of its convertible debt, as discussed in Note 6 
below. 

In September 2006, the FASB issued SFAS 157, “Fair Value Measurements”. SFAS 157 defines fair value, 
establishes a framework for measuring fair value in accordance with accounting principles generally accepted in 
the United States of America and expands disclosures about fair value measurements. SFAS 157 applies under 
other accounting pronouncements that require or permit fair value measurements. The Company was required to 
adopt SFAS 157 beginning January 1, 2008. In February 2008, the FASB released FASB Staff Position (FSP 
FAS 157-2 — Effective Date of FASB Statement No. 157), which delayed the effective date of SFAS No. 

37

 
 
 
 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

157 for all non-financial assets and liabilities, except those that are recognized or disclosed at fair value 
in the financial statements on a recurring basis (at least annually). The adoption of SFAS No. 157 for the 
Company’s financial assets and liabilities did not have a material impact on its consolidated financial statements. 
The Company does not expect that adoption of SFAS No. 157 for our non-financial assets and liabilities, 
effective January 1, 2009, will have a material impact on our financial statements. 

3.  Licensing and Research and Development Agreements 

On November 1, 2007, the Company signed an exclusive licensing agreement with Warner Chilcott Company, 
Inc., (“Warner”) for its topical alprostadil-based cream treatment for erectile dysfunction (“Vitaros®”).  Under the 
agreement, Warner acquired the exclusive rights in the United States to Vitaros® and would assume all further 
development, manufacturing, and commercialization responsibilities as well as costs.  Warner agreed to pay the 
Company an up front payment of $500,000 and up to $12.5 million in milestone payments on the achievement of 
specific regulatory milestones.   In addition, the Company was eligible to receive royalties in the future based 
upon the level of sales achieved by Warner, assuming the product is approved by the U.S. Food and Drug 
Administration (“FDA”).  

The Company has recognized the initial up-front payment as revenue on a straight line basis over the 9 month 
period ended July 31, 2008 which was the remaining review time by the FDA for the Company’s new drug 
application filed in September 2007 for Vitaros®.  Pursuant to the agreement, NexMed was responsible for the 
regulatory approval of Vitaros®. Accordingly, for the years ended December 31, 2008 and 2007, the Company 
recognized licensing revenue of $388,889 and $111,111, respectively, related to the Warner agreement. 

On February 3, 2009, the Company terminated the licensing agreement and sold the U.S. rights for Vitaros®  to 
Warner.  Under the terms of the agreement, the Company received an up-front payment of $2.5 million and is 
eligible to receive an additional payment of $2.5 million upon Warner’s receipt of a New Drug Application 
(NDA) approval for Vitaros® from the FDA.  As such, the Company is no longer responsible for the regulatory 
approval of Vitaros®   and will no longer be eligible to receive royalties in the future based upon the level of sales 
achieved by Warner.  In addition, Warner will pay a total of $350,000 for the manufacturing equipment for 
Vitaros®. While the Company believes that Warner is currently moving forward in pursuing NDA approval for 
Vitaros®. Warner is not obligated by the purchase agreement to continue with the development of Vitaros® or 
obtain approval of Vitaros® from the FDA.   

On September 15, 2005, the Company signed an exclusive global licensing agreement with Novartis International 
Pharmaceutical Ltd. (“Novartis”) for its anti-fungal product, NM100060.  Under the agreement, Novartis 
acquired the exclusive worldwide rights to NM100060 and would assume all further development, regulatory, 
manufacturing and commercialization responsibilities as well as costs.  Novartis agreed to pay the Company up to 
$51 million in upfront and milestone payments on the achievement of specific development and regulatory 
milestones, including an initial cash payment of $4 million at signing.  In addition, the Company is eligible to 
receive royalties based upon the level of sales achieved and is entitled to receive reimbursements of third party 
preclinical study costs up to $3.25 million.   The Company began recognizing the initial up front and preclinical 
reimbursement revenue from this agreement based on the cost-to-cost method over the 32-month period 
estimated to complete the remaining preclinical studies for NM100060.   On February 16, 2007, the Novartis 
agreement was amended.  Pursuant to the amendment, the Company is no longer obligated to complete the 
remaining preclinical studies for NM100060.   Novartis has taken over all responsibilities related to the remaining 
preclinical studies.  As such, the balance of deferred revenue of $1,693,917 at December 31, 2006 was 
recognized as revenue on a straight line basis over the 18 month period ended June 30, 2008 which was the 
performance period for Novartis to complete the remaining preclinical studies. Accordingly, for the years ended 
December 31, 2008 and 2007, the Company recognized licensing revenue of $564,639 and $846,960, 
respectively, related to the initial $4 million cash payment from the Novartis agreement. 

On March 4, 2008, the Company received a $1.5 million milestone payment from Novartis pursuant to the terms 
of the licensing agreement whereby the payment was due seven months after the completion of patient enrollment 

38

 
 
 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

for the Phase 3 clinical trials for NM100060, which occurred in July 2007.  Although the completion of patient 
enrollment in the Phase 3 clinical trials for NM100060 triggered a $3 million milestone payment from Novartis, 
the agreement also provided that clinical milestones paid to us by Novartis shall be reduced by 50% until the 
Company receives an approved patent claim on the NM100060 patent application filed with the U.S. patent office 
in November 2004.  The $1.5 million milestone payment was being recognized on a straight-line basis over the 
six month period to complete the Phase 3 clinical trial.  Accordingly, for the year ended December 31, 2008, the 
Company recognized licensing revenue of $1.5 million related to the $1.5 million milestone payment.   

In July 2008, Novartis completed testing for the Phase 3 clinical trials for NM100060 required for the filing of 
the NDA in the U.S.  On August 26, 2008, the Company announced that Novartis had decided not to submit the 
NDA in the U.S. based on First Interpretable Results of the Phase 3 trials. As a result of this decision, the 
Company will not receive a $6 million payment for positive Phase 3 results, and a $7 million milestone payment 
due upon filing of the NDA has been postponed indefinitely. 

On October 17, 2008, the Company received a Notice of Allowance for its U.S. patent covering NM100060.  
Pursuant to the license agreement, the payment of the issuance fee for an approved patent claim on NM100060 
triggered the $2 million patent milestone payment from Novartis.  Additionally, $1.5 million, which represents 
the remaining 50% of the patient enrollment milestone  also became due and payable.  As such the Company 
received a payment of $3.5 million from Novartis on October 30, 2008 and recognized it as licensing revenue for 
the year ended December 31, 2008.   

Novartis has confirmed that it intends to complete patient testing in the ongoing comparator study which they had 
initiated in March 2007 in ten European countries.  Over 900 patients with mild to moderate onychomycosis are 
participating in this open-label study, which is designed to assess the safety and tolerability of NM100060 
(terbinafine 10% topical formulation) versus Loceryl® (amorolfine) 5% nail lacquer, a topical treatment for 
onychomycosis that is approved in Europe. The comparator study is expected to be completed by early 2009 and 
the data will be available in mid-2009.  If the results of the comparator study are positive and the total clinical 
database is deemed to be sufficient for filing, the Company expects Novartis to begin filing for marketing 
approval in selected European countries while they develop a new plan of action for the U.S. market.  If the 
results are negative, the Company expects Novartis to terminate the global licensing agreement, which it can do 
at any time, and the rights to NM100060 would revert back to the Company with no compensation for 
termination.  

4.  Fixed Assets 

Fixed assets at December 31, 2008 and 2007 were comprised of the following: 

Land
Building, including impairment charge of $884,271 in 2008
Machinery and equipment
Computer software
Furniture and fixtures

2008

2007

$      

363,909
6,378,587
2,599,159
600,167
188,935
10,130,757

$      

363,909
7,371,607
2,630,155
600,167
188,935
11,154,773

Less: accumulated depreciation

(4,611,105)

(4,197,787)

$   

5,519,652

$   

6,956,986

39

 
 
 
 
 
 
 
 
 
  
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

Depreciation and amortization expense was $486,420, $621,870, and $842,087 for 2008, 2007 and 2006 
respectively, of which $188,825 related to capital leases for the year ended December 31, 2006.   

5.  Deferred Compensation 

On February 27, 2002, the Company entered into an employment agreement with Y. Joseph Mo, Ph.D., that had a 
constant term of five years, and pursuant to which Dr. Mo served as the Company's Chief Executive Officer and 
President.  Under the employment agreement, Dr. Mo is entitled to deferred compensation in an annual amount 
equal to one sixth of the sum of his base salary and bonus for the 36 calendar months preceding the date on which 
the deferred compensation payments commence subject to certain limitations, including a vesting requirement 
through the date of termination, as set forth in the employment agreement.  The deferred compensation is payable 
monthly for 180 months commencing on termination of employment.  Dr. Mo’s employment was terminated as 
of December 15, 2005.    The monthly deferred compensation payment through May 15, 2021 will be $9,158.  As 
of December 31, 2008 and 2007, the Company has accrued  $1,009,762 and $1,060,274 respectively, which is 
included in deferred compensation, based upon the estimated present value of the vested portion of the obligation. 

6.  Convertible Notes Payable 

June 2008 Convertible Notes 

On June 30, 2008, the Company issued convertible notes (the “Convertible Notes”) in an aggregate principal 
amount of $5.75 million.  The Convertible Notes are collateralized by the Company’s facility in East Windsor, 
New Jersey and $4.75 million of the Convertible Notes are due on December 31, 2011 (the “Due Date”) and $1 
million of the Convertible Notes were due on December 31, 2008.  The Convertible Notes are due and payable in 
cash or convertible into shares of Common Stock with $4.75 million convertible at $2 per share on or before the 
Due Date and $1 million convertible at $1.75 per share on or before December 31, 2008 at the holders’ option.  
The Convertible Notes have a coupon rate of 7% per annum, which is payable at the Company’s option in cash 
or, if the Company’s net cash balance is less than $3 million at the time of payment, in shares of Common Stock.  
If paid in shares of Common Stock, then the price of the stock issued will be the lesser of $0.08 below or 95% of 
the five-day weighted average of the market price of the Common Stock prior to the time of payment.  Such 
additional interest consideration is considered contingent and therefore would only be recognized upon 
occurrence.  

On October 16, 2008, the Company sold certain building equipment and received proceeds of $60,000 which was 
used to prepay a portion of the $4.75 million payment due on December 31, 2011.  On December 31, 2008, the 
Company paid the $1 million principal payment due in cash.  As such, the balance of $4,690,000 is due on 
December 31, 2011 and is recorded as Convertible notes payable on the consolidated balance sheets at December 
31, 2008.  As discussed in Note 3 above, the Company sold $350,000 of manufacturing equipment to Warner.  
The note holders agreed to release the lien on the equipment in exchange for a $50,000 repayment of principal to 
be paid in 2009 when the equipment is transferred to Warner.   

December 2003 Convertible Note 

On December 12, 2003, the Company issued convertible notes in an aggregate principal amount of $6 million.  
The notes were payable in two installments of $3 million on November 30, 2006 and May 31, 2007 and were 
collateralized by the Company’s facility in East Windsor, New Jersey.  The notes were convertible into shares of 
the Company’s Common Stock at a conversion price initially equal to $6.50 per share (923,077 shares).  Pursuant 
to the terms of the Notes, the conversion price was adjusted on June 14, 2004 to the greater of (i) the volume 
weighted average price of the Company’s stock over the six-month period ending on such date and (ii) $5.00.   
Since the volume weighted average price of the Company’s stock during this period was below $5.00, the 
conversion price was adjusted to $5.00 (1,200,000 shares).  Interest accreted on the notes on a semi-annual basis 
at a rate of 5% per annum, and the Company could pay such amounts in cash or by effecting the automatic 

40

 
 
 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

conversion of such amount into the Company’s Common Stock at a 5% premium to the then average market 
prices.    

In April and October 2006, respectively, the Company issued 164,855 shares and 227,612 shares of its Common 
Stock as payment of an aggregate of $304,167 in interest on the notes.   

On November 30, 2006, the Company paid in cash the $3 million installment due plus accrued interest of 
$25,417.  The remaining $3 million balance plus accrued interest of $25,417 on the note was paid on May 31, 
2007 such that no amounts remained outstanding at December 31, 2008 and 2007. 

For the year ended December 31, 2006, the Company recorded amortization of the debt issuance costs of 
$11,345. 

7. 

  Notes Payable 

October 2007 Note 

On October 26, 2007, the Company issued a note in a principal amount of $3 million.  The note was payable on 
June 30, 2009 and could be prepaid by the Company at any time without penalty.  Interest accreted on the note on 
a quarterly basis at a rate of 8.0% per annum.  The note was collateralized by the Company’s facility in East 
Windsor, New Jersey.  

The Company also issued to the noteholder a 5-year detachable warrant to purchase 450,000 shares of Common 
Stock at an exercise price of $1.52.  Of the total warrants issued, 350,000 warrants vest immediately and the 
remaining 100,000 warrants were to vest if the note had remained outstanding on October 26, 2008. The 
Company valued the warrants using the Black-Scholes pricing model.   The Company allocated a relative fair 
value of $512,550 to the warrants.  The relative fair value of the warrants is allocated to additional paid in capital 
and treated as a discount to the note that is being amortized over the 20-month period ended June 30, 2009. 

This note was paid on June 30, 2008 with the proceeds from the issuance of the Convertible Notes referred to 
above in Note 6.  The Company paid in cash the $3 million balance on the note plus accrued interest of $60,000.  
Additionally, the remaining 100,000 warrants that were to vest on October 26, 2008 were cancelled. 

For the years ended December 31, 2008 and 2007, the Company recorded $461,291 and 51,255, respectively, of 
amortization related to the note discount, including the acceleration of the amortization upon repayment. 

November 2006 Note 

On November 30, 2006, the Company issued a note in the principal amount of $2 million.  The note was payable 
on the earlier of December 31, 2007 or the closing by the Company on the sale of the Company’s facility in East 
Windsor, New Jersey.  Interest accreted on the note on a quarterly basis  at a rate of 7.5% per annum provided, 
however, if the Company had not entered into a contract of sale of the East Windsor property on or prior to May 
31, 2007, and the note had not been repaid by such date, the interest rate would increase to 8.5%.  As such, on 
May 31, 2007, the interest rate increased to 8.5%. 

On February 28, 2007, the Company issued 28,809 shares of its Common Stock as payment of an aggregate of 
$25,000 in interest on the note. 

On May 1, 2007, the Company issued 30,711 shares of its Common Stock as payment of an aggregate of $37,500 
in interest on the note.  

On August 1, 2007 the Company issued 26,518 shares of its Common Stock as payment of an aggregate of 
$40,833 in interest on the note. 

41

 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

The Company also issued the noteholder a 4-year detachable warrant to purchase 500,000 shares of Common 
Stock at an exercise price of $0.5535.  The Company valued the warrants using the Black-Scholes pricing model.   
The Company allocated a relative fair value of $138,000 to the warrants.  The relative fair value of the warrants 
was allocated to additional paid in capital and treated as a discount to the note that was being amortized through 
the October 2007 repayment date. 

This note was paid on October 29, 2007 with the proceeds from the issuance of the $3 million October 2007 note 
referred to above.  The Company paid in cash the $2 million balance on the note plus accrued interest of $42,028. 

For the year ended December 31, 2007, the Company recorded $127,385 of amortization related to the note 
discount. 

8.  Line of Credit 

On May 12, 2008 the Company entered into a Binding Commitment for a Credit Line (the “Commitment”), with 
one of its largest shareholders (the “Lender”).  Pursuant to the Commitment, the Company established a $3 
million credit line (the “Credit Line”) with the Lender, which was to expire on December 31, 2008.  The 
Company could draw down (“Draw Down”) on the Credit Line up to five times during the term of the Credit 
Line, and Draw Downs could not exceed $600,000 in any 30 day period.  In addition, the Company could only 
Draw Down when the Company’s cash and cash equivalents were below $1 million, and the Company was 
required to give the Lender at least 5 days’ notice prior to any Draw Down.  The Commitment provided that if the 
results from the Phase 3 trials on the Company’s anti-fungal product were negative, further Draw Downs on the 
Credit Line would be prohibited.    

The Company could repay the Draw Downs in either shares of Common Stock or cash at the Lender’s option on 
December 31, 2008.  If the Lender chose to be repaid with Common Stock, the number of shares of Common 
Stock issued would have been equal to the amount of the total Draw Down divided by $1.01, which was 92.5% of 
the 5 day volume weighted average price of the Company’s Common Stock for the 5 day period ended May 9, 
2008.   

In consideration of making available the Credit Line, the Lender received a warrant (the “Warrant”) to purchase 
250,000 shares of the Company’s Common Stock, which vested immediately upon the execution of the 
Commitment.  The Warrant has a 3 year term at an exercise price of $1.15, which is 105% of the 5 day volume 
weighted average price of the Company’s Common Stock for the 5 day period ended May 9, 2008. The Company 
valued the Warrant using the Black-Scholes pricing model.   The Company allocated a relative fair value of 
$114,750 to the Warrant.  The relative fair value of the Warrant is allocated to additional paid-in capital and 
treated as a debt issuance cost that was amortized over the period ending December 31, 2008.  

For the year ended December 31, 2008, the Company recorded $114,750 of amortization related to the debt 
issuance cost of the Credit Line.  There were no Draw Downs under the commitment during 2008. 

On August 26, 2008, the Company announced that Novartis had decided to not submit an NDA in the U.S. based 
on First Interpretable Results of the Phase 3 trials on the Company’s anti-fungal product. As such, the Credit Line 
was withdrawn by the Lender. 

9.  Stock Options and Restricted Stock 

 During December 1996, the Company adopted The NexMed, Inc. Stock Option and Long-Term Incentive 
Compensation Plan (“the Incentive Plan”) and The NexMed, Inc. Recognition and Retention Stock Incentive Plan 
(“the Recognition Plan”).  A total of 2,000,000 shares were set aside for these two plans.  In May 2000, the 
Stockholders’ approved an increase in the number of shares reserved for the Incentive Plan and Recognition Plan 
to a total of 7,500,000.  During June 2006, the Company adopted the NexMed, Inc. 2006 Stock Incentive Plan.  A 
total of 3,000,000 shares were set aside for the plan and an additional 2,000,000 shares were added to the plan in 
June 2008.  Options granted under the Company’s plans generally vest over a period of one to five years, with 

42

 
 
 
 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

exercise prices of currently outstanding options ranging between $0.55 to $16.25.  The maximum term under 
these plans is 10 years. 

The following table summarizes information about options outstanding at December 31, 2008: 

Options Outstanding

Weighted Average

Range of

Number 

Remaining

Weighted Average

Exercise Prices
$     .55 - 1.85
2.00 - 3.99
4.00 - 5.50
8.00 - 16.25

Outstanding
2,858,090
119,250
373,651
18,000

3,368,991

Contractual Life
6.98 years
2.69 years
3.64 years
1.44 years

Exercise Price
0.86
$     
2.88
4.65
8.67

Aggregate

Intrinsic

Value
$               

-
-
-
-

Options Exercisable

Number 

Weighted Average

Exercisable
2,666,686
119,250
373,651
18,000

Exercise Price
0.83
$      
2.88
4.65
8.67

Aggregate

Intrinsic

Value *
$                

-
-
-
-

$       

1.40

$               

-

3,177,587

$        

1.40

$                

-

*Intrinsic values are determined by comparing the aggregate exercise prices of options to the closing price of our Common Stock on December 31, 2008

A summary of stock option activity is as follows: 

Weighted
Average
Exercise
Price

Weighted
Average Remaining
Contractual
Life

Total
Aggregate
Intrinsic
Value

Outstanding at January 1, 2006

Granted
Exercised
Cancelled

Outstanding at December 31, 2006

Granted
Exercised
Cancelled

Outstanding at December 31, 2007

Granted
Exercised
Cancelled
Outstanding at December 31, 2008

Vested or expected to vest at
     December 31, 2008

Exercisable at December 31, 2008
Exercisable at December 31, 2007
Exercisable at December 31, 2006

Number of
Shares

5,018,880
1,993,750
(354,666)
(2,994,543)
3,663,421
202,100
(78,480)
(317,200)

3,469,841
-
(55,000)
(45,850)
3,368,991

$            

$            

2.83
0.78
0.71
3.28
1.52
1.41
1.07
2.82

$           

1.41

$           

$            

0.73
3.33
1.40

3,356,722

$           

1.40

3,177,586
3,122,740
2,395,897

$           
$           
$           

1.40
1.43
1.83

Options available for grant at December 31,  2008

373,203

43

5.25 years

5.25 years

5.05 years

$0

$0

$0

 
 
 
 
 
  
  
 
 
            
            
            
            
            
            
            
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

There were no options granted during 2008.  The weighted average grant date fair value of options granted during 
2007 and 2006 was $1.41, and $0.78, respectively.  The intrinsic value of options exercised during the year ended 
December 31, 2008 was $43,270. 

As of December 31, 2008, there was $119,401 of total unrecognized compensation cost related to non-vested 
stock options. That cost is expected to be recognized over a weighted-average period of 1.40 years. 

Compensatory Share Issuances 

The value of restricted stock grants is calculated based upon the closing stock price of the Company’s Common 
Stock on the date of the grant.  The value of the grant is expensed over the vesting period of the grant in 
accordance with SFAS 123R as discussed in Note 2.  As of December 31, 2008, there was $821,928 of total 
unrecognized compensation cost related to non-vested restricted stock.  That cost is expected to be recognized 
over a weighted-average period of 1.31 years. 

Principal employee based compensation transactions for the year ended December 31, 2008 were as follows:  

On January 9, 2008 the Company issued awards of shares of Common Stock to each non-employee Director as 
compensation for their services during the year ending December 31, 2008.  In lieu of cash compensation, the 
non-employee Directors have opted to receive, and the Board of Directors has approved, a full grant of 24,324 
shares of Common Stock to each non-employee Director for his services to be rendered to the Board of Directors 
during the 2008 calendar year.  The price per share (the "Price") is the average of the closing price of Common 
Stock over five consecutive trading days, commencing on January 2, 2008.  The number of the full grant of 
shares was calculated based on the amount of cash the Director would have received for annual service on the 
Board, or $36,000, divided by the Price.    

On August 12, 2008, the Compensation Committee of the Company’s Board of Directors approved a revised 
compensation package for the non-employee Directors for the 2008 calendar year.  Each non-employee member 
of the Board received an additional grant of 18,508 shares of the Company’s Common Stock bringing the total 
2008 shares granted to each non-employee director to 42,832.  The number of the full grant of shares was 
calculated based on the amount of cash the Director would have received for annual service on the Board, or 
$62,962, divided by the Price.    

The Compensation Committee also approved a revised compensation package for Richard Berman for his annual 
service as Chairman of the Board.  Mr. Berman received an additional grant of 57,835 shares of Common Stock 
bringing the total 2008 shares granted to him to 82,159.  The number of the full grant of shares was calculated 
based on the amount of cash Mr. Berman would have received for annual service as Chairman of the Board, or 
$120,773, divided by the Price.  Also, as part of the revised compensation package, the Board approved a one-
time grant, vesting immediately, to the Chairmen and members of the various committees of the Board for their 
annual service.  As such, the following shares of Common Stock were issued to the non-employee Directors on 
August 12, 2008: 

David Tierney received 50,000 shares as Chairman of the Scientific Advisory Board, 906 shares as a member of 
the Governance/Nominating Committee, and 906 shares as a member of the Compensation Committee. The 
number of the full grant of shares was calculated based on the amount of cash Mr. Tierney would have received 
for annual service as Chairman of the Scientific Advisory Board, member of the Governance/Nominating 
Committee, and member of the Compensation Committee, or $34,013, $1,333, and $1,333, respectively, divided 
by the Price. 

Leonard Oppenheim received 6,197 shares as the Chairman of the Audit Committee.  The number of the full 
grant of shares was calculated based on the amount of cash Mr. Oppenheim would have received for annual 
service as Chairman of the Audit Committee, or $9,111, divided by the Price.    

44

 
 
 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

Martin Wade received 3,287 shares as the Chairman of the Compensation Committee, 1,209 shares as a member 
of the Audit Committee, and 906 shares as a member of the Governance/Nominating Committee. The number of 
the full grant of shares was calculated based on the amount of cash Mr. Wade would have received for annual 
service as Chairman of the Compensation Committee, member of the Audit Committee, and member of the 
Governance/Nominating Committee, or $4,833, $1,778, and $1,333, respectively, divided by the Price. 

Arthur Emil received 1,587 shares as Chairman of the Governance/Nominating Committee, 1,209 shares as a 
member of the Audit Committee, and 906 shares as a member of the Compensation Committee. The number of 
the full grant of shares was calculated based on the amount of cash Mr. Emil would have received for annual 
service as Chairman of the Governance/Nominating Committee, member of the Audit Committee, and member of 
the Compensation Committee, or $2,333, $1,778, and $1,333, respectively, divided by the Price. 

On September 12, 2008, the Board of Directors approved new stock grants (“New Stock Grants”) for Hemanshu 
Pandya, the Company’s Chief Operating Officer and Mark Westgate, the Company’s Chief Financial Officer, 
with each grant comprised of 500,000 restricted shares of Common Stock.  The two New Stock Grants will vest 
in two equal installments on June 30, 2009 and June 30, 2010, respectively, provided that Mr. Pandya and Mr. 
Westgate remain in continuous and uninterrupted service with the Company. 

For the years ended December 31, 2007 and 2006, the Company granted 1,574,540 and 299,316 shares of 
restricted stock, respectively to officers and Directors. 

10.  Series C 6% Cumulative Convertible Preferred Stock 

On May 17, 2005, the Company sold an aggregate of 445 shares of its Series C 6% cumulative convertible 
preferred stock and raised gross proceeds of $4,450,000 ($10,000 liquidation preference per share).  Each 
preferred share of the Series C Stock was initially convertible at the holder’s option into approximately 7,353 
shares of Common Stock (total of 3,272,059 shares).  Each investor also received for each share of Series C 
Stock purchased, 4-year detachable warrants to purchase 2,672 shares of Common Stock (total of 1,188,931 
warrants) at an exercise price of $1.43 per share. The Series C Stock could be converted at any time, at the 
holder’s option, into shares of the Company’s Common Stock at an initial conversion value of $1.36.   

For the year ended December 31, 2006 pursuant to the terms of the Series C Stock, the Company recorded 
dividends in the amount of $15,264 as a dividend to preferred shareholders in the Consolidated Statements of 
Operations.   

For the year ended December 31, 2006 the Company recorded a deemed dividend of $49,897.  This deemed 
dividend represents the sum of the beneficial conversion feature, amortization of the contingent beneficial 
conversion feature, and amortization of preferred stock issuance costs. 

During 2005, the Company converted 357.5 shares of the Series C Stock and accrued dividends into 3,215,590 
shares of its Common Stock with an aggregate value of $3,482,974.  During the first half of 2006, the Company 
converted 72 shares of the Series C Stock and accrued dividends into 880,308 shares of its Common Stock with a 
value of $715,388. 

On June 30, 2006, pursuant to the terms of the Series C Stock, the Company converted the remaining 15.5 
preferred shares and accrued dividends through June 30, 2006 of $159,612 at a price of $0.65 per share.  Upon 
conversion, the Company issued a total of 244,113 shares of Common Stock.  As of December 31, 2008 and 
2007, no shares of the Series C Stock remained outstanding.  

11.  Common Stock 

Pursuant to a Common Stock and Warrant Purchase Agreement dated December 20, 2006, the Company closed a 
private placement of its securities and raised over $8.65 million in gross proceeds.  The Company sold 

45

 
 
 
 
 
 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

13,317,000 shares of its Common Stock at $0.6501 per share.  The investors also received four-year warrants to 
purchase 5,326,800 shares of Common Stock, exercisable beginning six months after closing at a price of $0.79 
per share.  The warrants will be redeemable by the Company at $0.01 per share if the closing sales price of its 
Common Stock is above $5 for ten consecutive trading days as reported on the Nasdaq Capital Market or other 
principal exchange.   

On January 23, 2006, the Company closed a private placement of its securities and raised over $8.3 million in 
gross proceeds.  The Company sold 9,347,191 shares of its Common Stock at $0.89 per share.  The investors also 
received four-year warrants to purchase 3,738,876 shares of Common Stock, exercisable beginning six months 
after closing at a price of $1.11 per share.  The warrants will be redeemable by the Company at $0.01 per share if 
the closing sales price of its Common Stock is above $5 for ten consecutive trading days as reported on the 
Nasdaq Capital Market or other principal exchange.     

12.  Stockholder Rights Plan 

On April 3, 2000, the Company declared a dividend distribution of one preferred share purchase Right for each 
outstanding share of the Company's Common Stock to shareholders of record at the close of business on April 21, 
2000.  One Right will also be distributed for each share of Common Stock issued after April 21, 2000, until the 
Distribution Date described in the next paragraph.  Each Right entitles the registered holder to purchase from the 
Company a unit consisting of one one-hundredths of a share (a Unit) of Series A Junior Participating Preferred 
Stock, $.001 par value per share, at a Purchase Price of $100.00 per Unit, subject to adjustment.  Under the 
Rights Plan, 1,000,000 shares of the Company’s preferred stock have been set-aside. 

Initially, the Rights will be attached to all Common Stock certificates representing shares then outstanding, and 
no separate Rights Certificates will be distributed.  The Rights will separate from the Common Stock and a 
Distribution Date will occur upon the earlier of (i) ten (10) business days following a public announcement that a 
person or group of affiliated or associated persons (an Acquiring Person) has acquired, or obtained the right to 
acquire, beneficial ownership of 15% or more of the outstanding shares of Common Stock , or (ii) ten (10) 
business days following the public announcement of a tender offer or exchange offer that would, if consummated, 
result in a person or group beneficially owning 15% or more of such outstanding shares of Common Stock, 
subject to certain limitations. 

Under the terms of the Rights Agreement, Dr. Y. Joseph Mo, the Company’s former CEO, will be permitted to 
increase his ownership to up to 25% of the outstanding shares of Common Stock, without becoming an Acquiring 
Person and triggering a Distribution Date. 

On January 16, 2007 the Rights Agreement was amended to exempt Southpoint Master Fund, LP and its affiliates 
from becoming an Acquiring Person within the meaning of the Rights Agreement, provided that Southpoint’s 
aggregate beneficial ownership of the Company’s Common Stock is less than 20% of the shares of Common 
Stock then outstanding. 

13.  Warrants 

A summary of warrant activity is as follows: 

46

 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

Outstanding at January 1, 2006

Issued (Notes 10 and 11)
Exercised
Cancelled

Outstanding at December 31, 2006

Issued (Note 7)
Exercised
Cancelled

Outstanding at December 31, 2007

Issued (Note 8)
Exercised
Cancelled

Outstanding at December 31, 2008
Exercisable at December 31, 2008

14. 

Income Taxes 

Common Shares
Issuable upon
Exercise

Weighted Weighted
Average
Average
Exercise Contractual

Price

Life

11,030,550
9,565,676
-
(471,199)
20,125,027
450,000
(2,790,495)
(5,344,578)
12,439,954
250,000
(471,910)
(100,000)
12,118,044
12,118,044

1.83
0.90
-
1.82
$1.33
$1.52
$1.83
$1.40
$1.23
$1.15
$0.89
$1.52
$1.23
$1.23

1.22 years
1.22 years

The Company has incurred losses since inception, which have generated net operating loss carryforwards of 
approximately $84 million for federal and state income tax purposes.  These carryforwards are available to offset 
future taxable income and expire beginning in 2014 through 2028 for federal income tax purposes. In addition, 
the Company has general business and research and development tax credit carryforwards of approximately 
$103.7 million.  Internal Revenue Code Section 382 places a limitation on the utilization of federal net operating 
loss carryforwards when an ownership change, as defined by tax law, occurs.  Generally, an ownership change, as 
defined, occurs when a greater than 50 percent change in ownership takes place during any three-year period.  
The actual utilization of net operating loss carryforwards generated prior to such changes in ownership will be 
limited, in any one year, to a percentage of fair market value of the Company at the time of the ownership 
change.  Such a change may have already resulted from the additional equity financing obtained by the Company 
since its formation. 

In 2006, 2007 and 2008, the Company was approved by the State of New Jersey to sell a portion of its state tax 
credits pursuant to the Technology Tax Certificate Transfer Program.  The Company has approximately $853,000 
in NJ tax credit benefits left available to sell at December 31, 2008, and was approved to sell net operating loss 
tax benefits of $1,053,547 in 2008, $905,515 in 2007, and $637,525 in 2006.  The Company received net 
proceeds of $937,657, $805,909, and $567,397 in 2008, 2007, and 2006, respectively, as a result of the sale of the 
tax credits, which has been recognized as received as an income tax benefit in the Consolidated Statements of 
Operations.  There can be no assurance that this program will continue in future years. 

The net operating loss carryforwards and tax credit carryforwards resulted in a noncurrent deferred tax benefit at 
December 31, 2008, 2007 and 2006 of approximately $42.8 million, $39.2 million and $35.6 million, 
respectively.  In consideration of the Company’s accumulated losses and the uncertainty of its ability to utilize 
this deferred tax benefit in the future, the Company has recorded a valuation allowance of an equal amount on 
such date to fully offset the deferred tax benefit amount. 

In June 2006, the FASB issued FIN No. 48, Accounting for Uncertainty in Income Taxes-an interpretation of 
FASB Statement No. 109 ("FIN 48") which clarifies the accounting for uncertainty in income taxes recognized in 
an enterprise's financial statements in accordance with FASB Statement No. 109, Accounting for Income Taxes. 
FIN 48 prescribes a recognition threshold and measurement criteria for the financial statement recognition and 
measurement of a tax position taken or expected to be taken in a tax return. FIN No. 48 also provides guidance on 

47

 
 
 
 
 
 
 
          
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

derecognition, classification, interest and penalties, accounting in interim periods, disclosure, and transition and 
defines the criteria that must be met for the benefits of a tax position to be recognized. The cumulative effect of 
the change in accounting principle must be recorded as an adjustment to opening retained earnings. Effective 
January 1, 2007, the Company adopted FIN No. 48 and determined that such adoption did not have a material 
impact on its financial statements. 

The reconciliation of income taxes computed using the statutory U.S. income tax rate and the provision (benefit) 
for income taxes for the years ended December 31, 2008, 2007 and 2006 are as follows: 

For the years ended
December 31,
2007

2006

2008

Federal statutory tax rate
State taxes, net of federal benefit
Valuation allowance
Sale of state net operating losses

(35%)
(6%)
41%
(15.35%)

(35%)
(6%)
41%
(8.40%)

(35%)
(6%)
41%
(6.59%)

Provision (benefit) for income taxes

(15.35%)

(8.40%)

(6.59%)

For the years ended December 31, 2008, 2007 and 2006, the Company’s effective tax rate differs from the federal 
statutory rate principally due to net operating losses and other temporary differences for which no benefit was 
recorded, state taxes and other permanent differences. 

15.  Commitments and Contingencies 

The Company was a party to clinical research agreements with a clinical research organization (“CRO”) in 
connection with a one-year open-label study for Vitaros® with commitments by the Company that initially totaled 
approximately $12.8 million.  These agreements were amended in October 2005 such that the total commitment 
was reduced to approximately $4.2 million.  These agreements provided that if the Company canceled them prior 
to 50% completion, the Company will owe the higher of 10% of the outstanding contract amount prior to the 
amendment or 10% of the outstanding amount of the amended contract at the time of cancellation.  On September 
30, 2008, the clinical research agreements were cancelled as it was determined that the one-year open-label study 
would no longer be required by the FDA for regulatory approval of Vitaros®.  As such, a cancellation fee of 
approximately $892,000 was accrued at September 30, 2008.  Pursuant to the terms of the clinical research 
agreement, the cancellation fee was not payable until December 15, 2008.  On December 31, 2008, the Company 
paid $300,000 toward the total cancellation fee.  The balance of approximately $592,000 is included in accounts 
payable and accrued expenses in the Consolidated balance sheets at December 31, 2008. 

The Company is a party to several short-term consulting and research agreements that, generally, can be 
cancelled at will by either party.  

We are subject to certain legal proceedings in the ordinary course of business.  We do not expect any such items 
to have a significant impact on our financial position. 

16.  Segment and Geographic Information 

The Company has only one active business segment: designing, developing, manufacturing and marketing 
pharmaceutical products.  The Company maintained development and business development operations in the 
United States and Hong Kong in 2005, 2006.  In September 2007, the Company ceased all operations in Hong 
Kong.   

48

 
 
 
 
 
 
 
 
NexMed, Inc. 
Notes to Consolidated Financial Statements 

Geographic information as of December 31, 2008, 2007 and 2006 is as follows: 

For the years ended December 31,
2008
2006
2007

Net revenues

United States
Hong Kong

$     

$    

5,957,491
-
5,957,491

$        

775,894
494,473
1,270,367

$    

$        

758,207
1,108,720
1,866,927

$    

All long-lived assets were located in the United States at December 31, 2008, 2007 and 2006.  

49

 
 
 
 
 
 
 
 
 
ITEM 9.    
FINANCIAL DISCLOSURE. 

CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND 

None. 

ITEM 9A. 

CONTROLS AND PROCEDURES. 

In accordance with Exchange Act Rules 13a-15 and 15d-15, the Company’s management carried out an 
evaluation with participation of the Company’s Chief Executive Officer and Chief Financial Officer, its principal 
executive officer and principal financial officer, respectively, of the effectiveness of the Company’s disclosure controls 
and procedures as of the end of the period covered by this report.  Based upon that evaluation, the Chief Executive 
Officer and Chief Financial Officer concluded as of the end of the period covered by this report that the Company’s 
disclosure control and procedures are effective.  There were no changes in the Company’s internal controls over 
financial reporting identified in connection with the evaluation by the Chief Executive Officer and Chief Financial 
Officer that occurred during the Company’s fourth quarter that have materially affected or are reasonably likely to 
materially affect the Company’s internal control over financial reporting.  

Management’s Report on Internal Control over Financial Reporting 

Our Management is responsible for establishing and maintaining adequate internal control over financial 

reporting, as such term is defined in Exchange Act Rule 13a-15(f).  Under the supervision and with the participation of 
our management, including our principal executive officer and principal financial officer, we conducted an evaluation 
of the effectiveness of our internal control over financial reporting based on the framework in Internal Control – 
Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission.  Based on 
our evaluation under such framework, our management concluded that our internal control over financial reporting was 
effective as of December 31, 2008. 

The effectiveness of our internal control over financial reporting as of December 31, 2008 has been audited by 

Amper, Politziner & Mattia, LLP, an independent registered public accounting firm, as stated in their report which is 
included herein.  

ITEM 9B. 

OTHER INFORMATION. 

None. 

PART III. 

ITEM 10. 

DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE. 

ELECTION OF DIRECTORS 

Our Amended and Restated Articles of Incorporation, as amended to date (the “Articles of Incorporation”) 

divide our Board of Directors into three classes.  The term of office for each class is arranged so that the term of office 
of one class expires at each successive Annual Meeting of Stockholders.  The Board of Directors currently consists of 
six members as follows: Class I directors, Vivian H. Liu and Martin R. Wade, III, whose terms expire in 2010; Class II 
directors, Richard J. Berman and Arthur D. Emil, Esq., whose terms expire in 2009 and, if re-elected at the 2009 
Annual Meeting, in 2012 and Class III directors, Leonard A. Oppenheim and David S. Tierney, MD, whose terms 
expire in 2011.   

At the 2009 Annual Meeting, the Stockholders will elect two directors to serve as Class II directors.  Each of 

the Class II directors who is elected at the 2009 Annual Meeting will serve until the Annual Meeting of Stockholders to be 
held in 2012, and until such director’s successor is elected or appointed and qualifies or until such director’s earlier 
resignation or removal.  The Board of Directors believes that nominees, Richard J. Berman and Arthur D. Emil, will stand 
for election and will, if elected, serve as Class II directors.  However, with respect to each nominee, in the event such 
nominee is unable or unwilling to serve as a Class II director at the time of the 2009 Annual Meeting, the proxies may be 

50

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
voted for any substitute nominee designated by the present Board of Directors to fill such vacancy or the Board of 
Directors may be reduced to no less than three members in accordance with the Articles of Incorporation. 

Our Corporate Governance/Nominating Committee has reviewed the qualifications of the nominees for Class 

II director and has recommended such nominees for election to the Board of Directors.   

Nominees for Director 

The following information was furnished to the Company by the nominees. 

Richard J. Berman has served on the Board of Directors since June 2002, as Chairman of the Board since June 

2007, and on the Finance Committee since June 2002.  From January 2006 to June 2007, Mr. Berman served as our 
President and Chief Executive Officer.  He also served as a member of the Audit Committee, Executive Compensation 
Committee, and Corporate Governance/Nominating Committee of the Board of Directors between June 2002 and 
January 2006.  Mr. Berman currently serves as Chairman of National Investment Managers, a public company in 
pension administration and investment management (OTC: NIVM.OB); Chairman of Fortress Technology Systems 
(homeland security), and Chairman of Morlex, Inc. (internet) (OTC: MORX.OB).  Mr. Berman is a director of eight 
public companies: NexMed, Inc., Morlex, Inc., National Investment Managers, Broadcaster, Inc. (OTC: BCSR.OB), 
Easylink Services International, Inc. (Nasdaq: ESIC), (OTC: NIVM.OB), Advaxis, Inc. (OTC: ADXS.OB), NeoStem, 
Inc. (ASE: NBS), and Fortress Technology Systems (listed on the Frankfurt Exchange).  From 1998-2000, he was 
employed by Internet Commerce Corporation (now Easylink Services International, Inc.) as Chairman and CEO.  
Previously, Mr. Berman worked at Goldman Sachs; was Senior Vice President of Bankers Trust Company, where he 
started the M&A and Leveraged Buyout Departments; created the largest battery company in the world by merging 
Prestolite, General Battery and Exide to form Exide Technologies (NASDAQ: XIDE); helped create what is now Soho 
(NYC) by developing five buildings; and advised on over $4 billion of M&A transactions.  He is a past director of the 
Stern School of Business of NYU where he obtained his BS and MBA.  He also has U.S. and foreign law degrees from 
Boston College and The Hague Academy of International Law, respectively.  

Arthur D. Emil, Esq., is and has been a director and a member of the Audit Committee, Executive 

Compensation Committee and the Corporate Governance/Nominating Committee of the Board of Directors since June 
2003.  Mr. Emil has been a practicing attorney in New York City for over forty years, including with Kramer Levin 
Naftalis & Frankel from 1994 to 2002 and with Cohen Tauber Spievack & Wagner from 2003 to present. Mr. Emil is a 
principal owner and chairman of Night Sky Holdings LLC, a company which owns several restaurants now operating in 
the New York area, which included Windows on the World, and operated the Rainbow Room from 1986 until 
December 1998.  Mr. Emil is the founding principal and shareholder of two real estate development firms with 
commercial, residential and mixed-use properties in Connecticut, New York and Ohio.  Mr. Emil has served as trustee 
for various non-profit organizations including The American Federation of Arts and the Montefiore Medical Center.  
Mr. Emil received his LLB from Columbia University.   Mr. Emil serves on the Board of Directors of National 
Investment Managers (OTC: NIVM.OB).    

Set forth below is certain information as of March 10, 2009 regarding our directors. 

DIRECTORS 

Name 

Age  Title 

Richard J. Berman 

66 

Chairman of the Board of Directors 

Arthur D. Emil, Esq. 

84 

Director 

Vivian H. Liu 

47 

Director, President & Chief Executive Officer 

Leonard A. Oppenheim 

62 

Director 

David S. Tierney, MD 

45 

Director 

Martin R. Wade, III 

59 

Director 

51

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Biographical information concerning each of the director nominees is set forth above under the caption 

“Election of Directors.”  Biographical information concerning the remaining directors of the Company is set forth 
below. 

Vivian H. Liu, is and has been a director and President and Chief Executive Officer of the Company since June 
2007, and Secretary since 1995.  Ms. Liu served as our Vice President of Corporate Affairs from September 1995 until 
December 2005, Acting Chief Executive Officer from December 2005 until January 2006, Executive Vice President 
and Chief Operating Officer from January 2006 to June 2007, Chief Financial Officer from January 2004 until 
December 2005, Acting Chief Financial Officer from 1999 to January 2004 and Treasurer from September 1995 
through December 2005.  In 1994, while we were in a transition period, Ms. Liu served as Chief Executive Officer. 
From 1985 to 1994, Ms. Liu was a business and investment adviser to the government of Quebec and numerous 
Canadian companies with respect to product distribution, technology transfer and investment issues. Ms. Liu received 
her MPA in International Finance from the University of Southern California and her BA from the University of 
California, Berkeley.  

Leonard A. Oppenheim, is and has been a director since 2004, and a member of the Audit Committee since 

January 2006 and Finance Committee since June 2006.  Mr. Oppenheim served as the Chairman of the Board from June 
2006 through June 18, 2007. His current term as a member of the Board of Directors expires in 2011..  Mr. Oppenheim 
retired from business in 2001 and has since been active as a private investor.  From 1999 to 2001, Mr. Oppenheim was 
a partner in Faxon Research, a company offering independent research to professional investors.  From 1983 to 1999, 
Mr. Oppenheim was a principal in the Investment Banking and Institutional Sales division of Montgomery Securities.  
Prior to that, he was a practicing attorney.  Mr. Oppenheim graduated from New York University Law School in 1976.   

David S. Tierney, MD, is and has been a director since January 2007, and a member of the Executive 
Compensation Committee and Corporate Governance/Nominating Committee since June 2007.  His current term as a 
member of the Board of Directors expires in 2011.  From August 2000 to April 2007, Dr. Tierney served as President 
and Chief Executive Officer of Valera Pharmaceuticals, Inc. (Nasdaq:VLRX).  Prior to joining Valera, Dr. Tierney was 
President of Biovail Technologies, a division of Biovail Corporation.  While there, Dr. Tierney had responsibility for all 
of Biovail’s research and development, regulatory and clinical activities. Prior to Biovail, he spent three years at 
Roberts Pharmaceutical Corporation as Senior Vice President of Drug Development with responsibility for all research 
and development activities, and overall responsibility for drug development, medical affairs, worldwide regulatory 
affairs and chemical process development, as well as being part of the executive management team. Prior to joining 
Roberts, Dr. Tierney spent eight years at Elan Corporation in a variety of management positions. Dr. Tierney received 
his medical degree from the Royal College of Surgeons in Dublin, Ireland and was subsequently trained in internal 
medicine.  He currently serves on the Board of Directors of Catalyst Pharmaceutical Partners, Inc. (Nasdaq: CPRX) and 
Bioject Medical Technologies Inc. (Nasdaq: BJCT). 

Martin R. Wade III is and has been a director and a member of the Audit Committee, Executive Compensation 

Committee, and Finance Committee of the Board of Directors since June 2003, and a member of the Corporate 
Governance/Nominating Committee since January 2004.  His current term as a member of the Board of Directors 
expires in 2010.    Mr. Wade is the Chief Executive Officer of Broadcaster, Inc. (BCSR.OB), an internet entertainment 
firm, and since 2000, has also served as the Chief Executive Officer of Bengal Capital Partners, LLC, a merger and 
acquisition firm.  From 2000 to 2001, Mr. Wade was director and Chief Executive Officer of Digital Creative 
Development Corp.  From 1998 to 2000, Mr. Wade was Managing Director of Prudential Securities Inc.  From 1975 to 
1998, Mr. Wade served in various executive positions at Salomon Brothers Inc., Bankers Trust Company, Lehman 
Brothers and Price Waterhouse Company.  Mr. Wade serves on the Boards of Directors of several companies, including 
Alliance One International (NYSE: AOI) and BCSR.  Mr. Wade holds an MBA from the University of Wyoming.  

There are no family relationships among the directors or executive officers of the Company. 

52

 
 
 
 
 
 
 
 
 
 
 
 
 
 
THE BOARD AND ITS COMMITTEES 

Meetings of the Board of Directors 

During the year ended December 31, 2008, six meetings of the Board of Directors were held.  Each director 

attended at least 75% of the aggregate number of meetings of the Board and the Committees of the Board on which they 
served during the periods that they served.  While we have no policy requiring attendance, in June 2008, all of the four 
independent directors were present at our 2008 Annual Meeting of Stockholders.  

Committees of the Board 

The Board of Directors currently has four committees: the Executive Compensation Committee, the Audit 

Committee, the Finance Committee, and the Corporate Governance/Nominating Committee.   

The Executive Compensation Committee establishes remuneration levels for our executive officers and 

implements incentive programs for officers, directors and consultants, including the 2006 Stock Incentive Plan (the 
2006 Plan), the NexMed Inc. Stock Option and Long-Term Incentive Compensation Plan (the Stock Plan) and the 
Recognition and Retention Stock Incentive Plan (the Recognition Plan) (the Stock Plan and the Recognition Plan both 
expired in 2006).  The Executive Compensation Committee was formed on February 7, 2000 and met one time in 2008.  
As of December 31, 2008, the Executive Compensation Committee consisted of Arthur D. Emil, Dr. David S. Tierney 
and Martin R. Wade, III (Chairman), none of whom was an employee and each of whom met the independence 
requirements of NASDAQ Marketplace Rule 4200 (a)(15).  There is currently no charter for our Executive 
Compensation Committee.   Our independent compensation consultants as well as executive officers and management 
play an important role in making recommendations and formulating compensation plans for our employees, including 
named executives.  The Committee may delegate authority for day-to-day administration and interpretation of the 
various compensation programs in place, including selection of participants, determination of award levels and approval 
of award documents to our officers.  However, the Committee may not delegate any authority under those programs for 
matters affecting the compensation and benefits of the executive officers.  Our CEO, with input from our director of 
human resources, gives the Committee a performance assessment and compensation recommendations for the named 
executives.  Our director of human resources engaged and works closely with our independent compensation 
consultants, ORC Worldwide Compensation Consultants, who assist in evaluating our executive compensation program 
and were instructed to provide additional assurance that our program is reasonable and consistent with pharmaceutical 
industry standards for companies in our peer group. ORC Worldwide Compensation Consultants is a compensation 
consulting firm which provides consulting and data services to large and mid-sized organizations, focusing on 
compensation programs.  We participate in SIRS®, a Salary Information Retrieval System, which is a comprehensive 
U.S. salary survey with analytical tools and reports, whereby we select approximately fifty pharmaceutical companies 
with which we share salary data information on an annual basis.  This process enables us to benchmark our job 
functions and job levels within our specific industry sector, obtain competitive salary data, and maintain a competitive 
salary structure.  The recommendations of our CEO and director of human resources are then considered by the 
Committee in determining the total compensation packages for named executives.   

The Audit Committee periodically meets with our financial and accounting management and independent 

auditors and selects our independent auditors, reviews with the independent auditors the scope and results of the audit 
engagement, approves professional services provided by the independent auditors, reviews the independence of the 
independent auditors and reviews the adequacy of the internal accounting controls.  The Audit Committee was formed 
on February 7, 2000 and acts under a written charter first adopted and approved by the Board on the same date, and 
subsequently amended and approved on May 7, 2001, October 29, 2002 and May 24, 2004.  A copy of the Amended 
Audit Committee charter is posted on the Company’s website at www.nexmed.com.  The Audit Committee met three 
times in 2008, and as of December 31, 2008, consisted of Arthur D. Emil, Leonard A. Oppenheim (Chairman) and 
Martin R. Wade, III, none of whom was an employee and each of whom met the independence and experience 
requirements of Nasdaq Capital Market listing requirements.  The Board of Directors has determined that Mr. Wade, in 
addition to being “independent”, is an “audit committee financial expert,” as defined in Item 407(d)(5) of the SEC’s 
Regulation S-K.   

53

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
The Finance Committee makes recommendations to the Board of Directors concerning financing opportunities 

and instruments.  The Finance Committee was formed on June 21, 2002.  The Finance Committee met one time in 
2008, and consists of Richard J. Berman, Leonard A. Oppenheim and Martin R. Wade, III. 

The Corporate Governance/Nominating Committee makes recommendations to the Board of Directors 
concerning candidates for Board vacancies.  The Corporate Governance/Nominating Committee was formed on 
February 7, 2000.  The Corporate Governance/Nominating Committee met one time in 2008, and as of December 31, 
2008, consisted of Arthur D. Emil (Chairman), Dr. David S. Tierney and Martin R. Wade, III.   The Corporate 
Governance/Nominating Committee acts under a written charter, which is available on our website at 
www.nexmed.com.  As of December 31, 2008, each of the members of the Committee met the independence 
requirements of NASDAQ Capital Market listing standards.  We have not paid any third party a fee to assist in the 
process of identifying and evaluating candidates for director.  We have not received any nominees for director from a 
Stockholder or Stockholder group that owns more than 5% of our voting stock. 

The Company’s Corporate Governance/Nominating Committee may consider nominees for director submitted 

in writing to the Chairman of the Committee, which are submitted by our executive officers, current directors, search 
firms engaged by the Committee, and by others in its discretion and, in the circumstances provided below, shall 
consider nominees for director proposed by a Stockholder.  Information with respect to the proposed nominee shall be 
provided in writing to the Chairman of the Corporate Governance/Nominating Committee at NexMed, Inc., 89 Twin 
Rivers Drive, East Windsor, NJ 08520, at least 120 days prior to the anniversary of the date of the prior year’s Annual 
Meeting proxy statement.  A submitting Stockholder shall provide evidence that he, she or it has beneficially owned at 
least 5% of our Common Stock for at least one year and shall provide the name of the nominee, and such other 
information with respect to the nominee as would be required under the rules and regulations of the Securities and 
Exchange Commission to be included in our Proxy Statement if such proposed nominee were to be included therein.  In 
addition, the Stockholder shall include a statement to the effect that the proposed nominee has no direct or indirect 
business conflict of interest with us, and otherwise meets our standards set forth below.   

Any other Stockholder communications intended for our management or the Board of Directors shall be 

submitted in writing to the Chairman of the Corporate Governance/Nominating Committee who shall determine, in his 
discretion, considering the identity of the submitting Stockholder and the materiality and appropriateness of the 
communication, whether, and to whom within our Company, to forward the communication. 

The Corporate Governance/Nominating Committee generally identifies potential candidates for director by 
seeking referrals from our management and members of the Board of Directors and their various business contacts.  
There are currently no specific, minimum or absolute criteria for Board membership.  Candidates are evaluated based 
upon factors such as independence, knowledge, judgment, integrity, character, leadership, skills, education, experience, 
financial literacy, standing in the community and ability to foster a diversity of backgrounds and views and to 
complement the Board’s existing strengths.  There are no differences in the manner in which the Committee will 
evaluate nominees for director based on whether the nominee is recommended by a Stockholder.   

The Company has adopted a code of ethics that applies to its Chief Executive Officer, Chief Financial Officer, 

and to all of its other officers, directors and employees.  The code of ethics is available at the Corporate Governance 
section of the Investors page on the Company’s website at http://www.nexmed.com.  The Company intends to disclose 
future amendments to, or waivers from, certain provisions of its code of ethics, if any, on the above website within four 
business days following the date of such amendment or waiver.   

SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE 

Section 16(a) of the Securities Exchange Act of 1934, as amended, (the Exchange Act) requires our executive 
officers, directors and persons who beneficially own greater than 10% of a registered class of its equity securities to file 
certain reports with the Securities and Exchange Commission with respect to ownership and changes in ownership of 
the Common Stock and our other equity securities.   

Based solely on our review of the copies of such reports furnished to us and written representations that no 

other reports were required, our officers, directors and greater than ten percent stockholders complied with these 
Section 16(a) filing requirements with respect to the Common Stock during the fiscal year ended December 31, 2008.  

54

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ITEM 11. 

EXECUTIVE COMPENSATION. 

DIRECTOR COMPENSATION 

In 2001, the Board of Directors adopted a stock option and cash compensation package for its non-employee 

directors.  Upon joining the Board, each new non-employee director received a stock option and/or restricted stock 
package issued pursuant to the Recognition Plan which expired in 2006, or the the 2006 Plan which generally vests over 
a period of several years from the date of grant based on continuous and uninterrupted service to NexMed.  Prior to 
2007, the Company granted each director a stock option grant equal to 20,000 options, vesting immediately, upon 
commencement of his initial term.  Additionally, upon commencement of each three year term, each director received 
an option to purchase 60,000 shares of Common Stock which vest equally on the first, second and third anniversaries of 
the date of the grant.  Each director also received a cash payment of $500 per Board meeting.   

Beginning in 2007, the Board of Directors modified the stock and cash compensation package for its non-

employee directors such that each non-employee director received a grant of restricted stock rather than stock options.  
Each non-employee director received a stock grant of 10,000 shares of Common Stock, vesting immediately, upon 
commencement of his initial term.  Additionally, upon commencement of his initial term, each director received a 
restricted stock grant of 10,000 shares for each year of his term with 10,000 shares vesting on the date of each annual 
stockholder’s meeting during his term.  Dr. David Tierney, who was appointed in 2007, is the only director who has 
received such grant of restricted stock.  All other directors were compensated with stock option grants as discussed in 
the previous paragraph.    

In August 2008, the Board of Directors again modified the stock and cash compensation package for its non-

employee directors in order to achieve total compensation packages that were consistent with competitive 
pharmaceutical company market data.  As such, a Board compensation survey from Equilar, Inc., a compensation 
survey specialist used by many NASDAQ companies, was requested and reviewed by the Executive Compensation 
Committee.  The Executive Compensation Committee determined that the Company’s compensation packages differed 
significantly from the data in the survey in that the Company did not pay any additional compensation to the Chairman 
of the Board or the various Committee members and compensation to the Audit Committee Chairman was generally 
below the other companies in the survey.  Additionally, it was found that most companies in the survey compensated 
directors in both cash and stock and each board member received a fee based on the number of meetings held and 
attended.  

As a result of reviewing the Board compensation survey in August 2008, the Board implemented a new stock 

and cash compensation package effective January 1, 2008 for the annual retainer.  Under the new compensation 
package, each member of the Board and the various committees would receive an annual retainer in shares of Common 
Stock calculated using the average of the closing price of Common Stock over five consecutive trading days, 
commencing on January 2, 2008 (the “Price”).  The number of the full grant of shares was calculated based on the 
amount of cash the director would have received for annual service on the Board, as outlined in the table below, divided 
by the Price.  Additionally, each director would receive cash payments for individual Board meetings.  The new 
compensation package, which was effective January 1, 2008 for the annual retainer and August 2008 for the meeting 
fees, is as follows: 

55

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Title 
Chairman of the Board 

Board Member 

Audit Committee Chair 
Compensation 
Committee Chair 
Governance/Nominating 
Committee Chair 
Finance Committee 
Chair 
Audit Committee 
Member 
Compensation 
Committee Member 
Governance/Nominating 
Committee Member 
Finance Committee 
Member 

Annual Retainer 

In person Board 
Meeting Fee 

Telephone Board 
Meeting Fee 

$1,750 

$120,773 (82,159 
shares) 
$62,962 (42,832 
shares) 
$9,111 (6,197 shares)  $1,250 
$4,833 (3,287 shares)  $1,150 

$1,500 

$2,333 (1,587 shares)  $1,150 

$0 

$0 

$1,778 (1,209 shares)  $1,250 

$1,333 (906 shares) 

$1,250 

$1,333 (906 shares) 

$1,150 

$0 

$0 

$1,000 

$700 

$600 
$600 

$600 

$0 

$600 

$600 

$600 

$0 

This approach is consistent with the Company’s overall director compensation strategy to align the interests of 

the directors with those of the Stockholders over the long-term since the full benefits of the compensation package 
cannot be realized unless stock price appreciation occurs over a number of years. 

Additionally, in 2007, the Board established a Scientific Advisory Board (SAB) and appointed Dr. David S. 
Tierney to serve as the Chairman of the SAB.  The Board approved a stock grant of 20,000 shares of the Company’s 
Common Stock to Dr. David S. Tierney, pursuant to the 2006 Plan for services rendered in 2007.  The Board approved 
another stock grant in 2008 of 50,000 shares for services rendered in 2008.  

Total non-employee director compensation for 2008 was as follows: 

NON-EMPLOYEE DIRECTOR COMPENSATION FOR 2008 

 Fees earned or 
Paid in cash($) 

Stock Awards ($) 
(1) 

Option Awards ($) 
(1) 

Name 
(9) 

(a) 

Richard J. Berman 

Arthur D. Emil, Esq.  

Leonard A. Oppenheim  

David S. Tierney, MD 

Martin R. Wade, III  

(b) 

$1,000 

$1,300 

$1,300 

$700 

$600 

Total 
($) 

(h) 

$123,530 

$84,757 

$82,745 

(c) 

$122,530 (2) 

(d) 

$-- (10) 

$69,905 (8)  

$13,552 (3) 

$73,528 (4) 

$7,917 (5) 

$140,627 (6) 

$-- 

$141,327 

$70,904 (7) 

$ --(10) 

$71,504 

(1)  Market values for stock awards granted for the annual retainer fee were calculated based on the average of the closing price of 
our Common Stock over five consecutive trading days, commencing on January 2, 2008.  Market values for other stock awards 
were determined by multiplying the number of shares granted by the closing market price of the Company’s stock on the grant 
date in accordance with SFAS 123R.  The value of the option awards was calculated using the Black-Scholes method in 

56

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
accordance with SFAS 123R.  A discussion of the assumptions used in calculating the Black-Scholes values may be found in 
Note 2 and Note 9 of our Consolidated Financial Statements in Part II, Item 8. 

(2)  This amount represents our expense in 2008 for a grant of 82,159 shares as compensation for services as Chairman in 2008 and 

a grant of 13,258 shares in lieu of cash for a Board meeting fee in September 2008. 

(3)  This amount represents our expense in 2008 for an option to purchase 60,000 shares of Common Stock granted to Mr. Emil in 

August 2006 which vests in three equal installments in June 2007, 2008 and 2009.   

(4)  This amount represents our expense in 2008 for a grant of 42,832 shares as compensation for services as a Board member, 6,197 
shares as compensation for services as Chairman of the Audit Committee in 2008, and 11,364 shares in lieu of cash for a Board 
meeting fee in September 2008. 

(5)  This amount represents our expense in 2008 for an option to purchase 60,000 shares of Common Stock granted to Mr. 

Oppenheim in June 2005 which vested in three equal installments in June 2006, 2007 and 2008.  

(6)  This amount represents our expense in 2008 for a grant of 42,832 shares as compensation for services as a Board member, 

50,000 shares as compensation for services as Chairman of the SAB, 906 shares as compensation for services as a member of 
the Executive Compensation Committee, 906 shares as compensation for services as member of the Corporate 
Governance/Nominating Committee, and 11,364 shares in lieu of cash for a Board meeting fee in September 2008.      

(7)  This amount represents our expense in 2008 for a grant of 42,832 shares as compensation for services as a Board member, 3,287 

shares as compensation for services as Chairman of the Executive Compensation Committee, 1,209 shares as compensation for 
services as a member of the Audit Committee, and 906 shares as compensation for services as a member of the Corporate 
Governance/Nominating Committee. 

(8)  This amount represents our expense in 2008 for a grant of 42,832 shares as compensation for services as a Board member, 1,587 

shares as compensation for services as Chairman of the Corporate Governance/Nominating Committee, 1,209 shares as 
compensation for services as a member of the Audit Committee, 906 shares as compensation for services as a member of the 
Executive Compensation Committee, and 11,364 shares in lieu of cash for a Board meeting fee in September 2008. 

(9)  As of December 31, 2008: Mr. Berman had no shares of unvested restricted stock and options to purchase 1,150,000 shares of 
Common Stock outstanding; Mr. Emil had no shares of unvested restricted stock and options to purchase 140,000 shares of 
Common Stock outstanding; Mr. Oppenheim had no shares of unvested restricted stock and options to purchase 500,000 shares 
of Common Stock outstanding; Dr. Tierney had no options outstanding; and Mr. Wade had no shares of unvested restricted 
stock and options to purchase 100,000 shares of Common Stock outstanding.  

(10) No expense was recorded in 2008 for options issued in previous years. 

EXECUTIVE COMPENSATION 

Compensation Discussion & Analysis 

Introduction 

The objective of our executive compensation program is to link corporate performance and the total return to 
Stockholders over the long-term.  More specifically, the compensation program is designed to reward the achievement 
of corporate goals which are set at the beginning of each fiscal year and are communicated to all employees by the 
CEO, retain the executive employees over long-term periods, and use performance-based equity awards tied to the 
corporate goals in order to retain and reward the executive employees through the achievement of such goals.   In 2008, 
as in 2007, the overarching goals were to continue to maintain a low cash “burn rate”, to continue to advance our 
NexACT®-based products through our own targeted development activities, and to secure additional strategic 
collaborations and partnerships.   Tied to these broad goals were the following specific corporate goals:  manage our 
alliances with Novartis and Warner, support three filings - the NDA in the U.S., the MAA  in Europe, and the NDS in 
Canada for Vitaros®, prepare our East Windsor facility for the commercial manufacturing of Vitaros®, develop one 
new program up through the IND (Investigational New Drug) stage (i.e., advance our psoriasis program into clinical 
development), advance business development efforts for products under development and for our technology, maintain 
compliance with SEC requirements for a public company, develop new applications and the next generation of 
NexACT® technology, and develop and implement a process for project selection and project management.      

The elements of our executive compensation during the last fiscal year for our executives under employment 

agreements consisted of base salary, an annual cash bonus, and the granting of performance-based and incentive stock.   

Base Salaries 

The Executive Compensation Committee approves the salaries of our executives and exercises oversight over 

the compensation of the executives.   In establishing 2008 salary levels for our named executives (each of which was set 
forth in the employment agreements as described below), the Executive Compensation Committee placed the most 
emphasis on retaining the current executive officers and on recruiting an external executive candidate in order to 

57

 
 
 
 
 
 
 
 
 
 
 
 
 
advance our current products under development.  In addition, competitive pharmaceutical company market data for 
these three positions was obtained from ORC Worldwide Compensation Consultants and was used as a reference point 
for the salaries.    

Bonuses 

Cash bonuses are awarded to our named executives based upon a subjective evaluation by the Executive 

Compensation Committee, with recommendations from the CEO, based on an assessment of the performance of the 
executives during the year.   In assessing the performance of the executives, the CEO and the Executive Compensation 
Committee prioritize the importance of each of the corporate goals, assess the individual contributions made by each of 
the executives, and determine overall progress achieved.   As outlined in the introduction to the “Compensation 
Discussion & Analysis” section, the CEO and Board of Directors determine our corporate goals annually at the onset of 
the year upon approval of the annual budget.  No bonuses were paid to the named executives in 2008, as the annual 
corporate goals were not achieved in their entirety.    The Executive Compensation Committee determined that the 
substantial decline of the market capitalization of the Company and the failure to receive significant cash milestone 
payments, both of which were a direct result of the Novartis Phase 3 clinical trial results released in August 2008, 
significantly impacted executive bonus entitlement for the year.  Thus, major importance was placed upon Novartis’ 
decision not to file the NDA in the U.S. in 2008 due to insufficient clinical data. 

Stock and Stock Options  

Under the Stock Plan, which was adopted by the Company in December 1996 and expired in December 2006, 
and the 2006 Plan which was adopted on March 7, 2006, the Company’s employees, including executives, are eligible 
to receive stock options, stock appreciation rights, restricted stock, and other stock based awards.  The Executive 
Compensation Committee, with input from management, is responsible for approving stock and stock option grants to 
the Company’s employees.  In determining the size and type of awards, the nature of the position held as well as 
individual contributions of the employees toward achieving our corporate goals for the year and the need to retain key 
employees through the completion of critical projects over time are taken into consideration.  

Stock options and restricted stock awarded under the Stock Plan and the 2006 Plan, generally vest evenly over 
a period of three years from the date of grant.  Our 10-year options, granted at the market price on the date of the grant, 
help align the interests of the executive officers with those of the Stockholders over the long term since the full benefits 
of the compensation package cannot be realized unless stock price appreciation occurs over a number of years.  In 
addition, the options and restricted stock awards help to retain key employees because they typically cannot be fully 
exercised until the end of the three year vesting period and, if not exercised, are forfeited if the employee terminates 
employment with the Company.   Performance-based stock and stock option awards vest upon the achievement of 
specific corporate goals.  This approach helps to focus employees on specific corporate goals and retain employees who 
are integral in achieving such goals. 

Compensation of Chief Executive Officer 

Effective on June 18, 2007, we entered into a three-year employment agreement with Ms. Liu, pursuant to 

which she serves as our President and Chief Executive Officer.  During her employment, Ms. Liu will receive an annual 
base salary of at least $300,000, and is eligible to earn an annual bonus up to 50% of her annual base salary based upon 
the achievement by the Company of objective performance measures established and determined at the beginning of 
each fiscal year by the Board of Directors or the Executive Compensation Committee, in consultation with Ms. Liu. 

Ms. Liu’s agreement provides for grants of stock under the 2006 Plan.   The Executive Compensation 
Committee determined, based on their analysis of competitive market data compiled by the director of human 
resources, that our CEO should have a total equity compensation package such that she would achieve an ownership of 
approximately 2% of our outstanding Common Stock taking into account options and restricted stock already held by 
her at such time.  Therefore upon Ms. Liu’s acceptance of the position as CEO, she was awarded a restricted stock grant 
of a total of 850,000 shares.  100,000 shares vested immediately with the remaining 750,000 shares vesting in three 
equal installments of 250,000 shares on each June 18, 2008, 2009 and 2010. 

Additionally, in 2008 the Board approved performance-based stock grants to the three named executives, 

including Ms. Liu, which vest in two equal installments upon the re-submission of the NDA for Vitaros® and upon the 

58

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
FDA’s approval of the NDA.  Ms. Liu’s award is 100,000 shares of Common Stock.  As discussed in Note 3 of our 
Consolidated Financial Statements in Part II, Item 8, the U.S. rights to Vitaros® were sold to Warner and the FDA 
approval of Vitaros® is now the responsibility of Warner. The number of shares awarded in this grant was determined 
such that Ms. Liu would achieve an ownership percentage approaching approximately 2% of our outstanding Common 
Stock as CEO.   

Prior to Ms. Liu’s appointment as CEO, she was awarded a restricted stock grant of 150,000 shares in January 
2007.  The award vests in three equal installments of 50,000 shares on each December 31, 2007, 2008 and 2009.  This 
award  was  intended  to  retain  Ms.  Liu  in  her  position  as  COO  while  the  Board  made  a  decision  as  to  whether  the 
Company would recruit an external candidate for either the CEO or the COO position in 2007.  Additionally, this award 
was  to  recognize  the  progress  made  by  the  Company  in  2006,  to  acknowledge  Ms.  Liu’s  contributions  towards  that 
progress, and to remain competitive with industry compensation standards.  

Ms. Liu also received an award of 200,000 shares of restricted Common Stock in April 2006.  The award 

vested on December 31, 2006.  This stock grant was awarded as part of a corporate retention program implemented in 
April and September of 2006 in order to offer all employees, including named executives, a substantial monetary 
incentive to remain employed with us following the substantial lay-off and restructuring which occurred at the end of 
2005 and into 2006. 

The number of shares awarded in the 2006 and 2007 stock option and restricted Common Stock grants was 

determined such that Ms. Liu would achieve an ownership percentage approaching approximately 1% of our 
outstanding Common Stock as COO.  The Executive Compensation Committee determined, based on their analysis of 
competitive market data compiled by the director of human resources, that our named executive officers, other than our 
CEO, should have a total equity compensation package in order to achieve such ownership percentage. 

Ms. Liu’s employment agreement provides that, in the event of termination of her employment for “Cause” (as 

defined in the employment agreement), or death and disability, Ms. Liu would be entitled to receive any earned but 
unpaid base salary, bonus and benefits.  In the event of the termination of Ms. Liu’s employment without Cause, by Ms. 
Liu with “Good Reason” (as defined in the employment agreement) or upon a change in control (as defined in the 
employment agreement), Ms. Liu would be entitled to receive any earned but unpaid base salary, bonus and benefits in 
an amount equal to twelve months of her annual base salary at the time of such termination.   In addition, Ms. Liu’s 
outstanding but unvested restricted stock and stock options would vest immediately.   

Compensation of Chief Operating Officer 

 On October 31, 2007, we entered into a one-year employment agreement with Hemanshu Pandya, pursuant to 

which he serves as our Vice President.  The employment agreement was automatically renewed on October 31, 2008 
for another one-year term.  During his employment, Mr. Pandya will receive an annual base salary of at least $225,000, 
and is eligible to earn an annual bonus of up to 50% of his annual base salary based upon the achievement by the 
Company of objective performance measures established and determined at the beginning of each fiscal year by the 
Board of Directors or its Executive Compensation Committee, in consultation with Ms. Liu and Mr. Pandya.    

Mr. Pandya’s agreement provides for grants of options to purchase shares of our Common Stock under the 
2006 Plan.  These options are intended to be incentive stock options to the fullest extent permitted under the Internal 
Revenue Code.  In October 2007, Mr. Pandya received an option award to purchase a total of 175,000 shares of our 
Common Stock at $1.43 per share, the market price of our Common Stock at the time of the grant. The award vests in 
three installments of 25,000 options on October 31, 2008, 50,000 options on October 31, 2009 and 100,000 options on 
October 31, 2010.   

Mr. Pandya’s agreement also provides for grants of stock under the 2006 Plan.  On October 31, 2007, Mr. 

Pandya was awarded a restricted stock grant of 125,000 shares.  75,000 shares will vest in three equal installments of 
25,000 shares each on October 31, 2008, 2009 and 2010.  The remaining 50,000 shares vest only upon the execution of 
a licensing/development agreement brought to the Company by Mr. Pandya valued at over $5 million on or before April 
30, 2009.  In light of Mr. Pandya’s efforts in connection with the sale of the U.S. rights to Vitaros® to Warner as 
discussed in Note 3 of the Consolidated Financial Statements in Part II, Item 8, on February 2, 2009 the Board approved 
the vesting of the remaining 50,000 shares. 

59

 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
Additionally, in 2008 the Board approved performance-based stock grants to the three named executives, 

including Mr. Pandya, which vest in two equal installments upon the re-submission of the NDA for Vitaros® and upon 
the FDA’s approval of the NDA.  Mr. Pandya’s award is 100,000 shares of Common Stock.   As discussed in Note 3 of 
the Consolidated Financial Statements in Part II, Item 8, the U.S. rights to Vitaros®  were sold to Warner and the FDA 
approval of Vitaros® is now the responsibility of Warner. 

Mr. Pandya’s total compensation package (salary, bonus, stock options and restricted stock) was reviewed and 
approved by the Executive Compensation Committee after a discussion with our human resources director and a review 
of competitive pharmaceutical company market data supplied by ORC Worldwide Compensation Consultants for his 
position as COO.  It was determined that his total compensation package is competitive with industry compensation 
standards.    

The number of shares awarded in the above mentioned stock option grants and restricted Common Stock 

grants was determined such that Mr. Pandya would eventually achieve an ownership percentage approaching 1% of the 
Company as COO.  The Executive Compensation Committee determined, based on their analysis of competitive market 
data compiled by the director of human resources, that our named executive officers, other than our CEO, should have a 
total equity compensation package in order to achieve such ownership percentage.  Accordingly, on October 3, 2008 the 
Executive Compensation Committee approved a grant of 500,000 shares vesting in two equal installments on June 30, 
2009 and 2010.  This new grant in 2008 brought Mr. Pandya’s ownership percentage (vested and unvested) as of 
December 31, 2008 to approximately 0.8%. 

Mr. Pandya’s employment agreement provides that, in the event of termination of his employment for “Cause” 
(as defined in the employment agreement), or death and disability, Mr. Pandya would be entitled to receive any earned 
but unpaid base salary, bonus and benefits.  In the event of the termination of Mr. Pandya’s employment without Cause, 
by Mr. Pandya with “Good Reason” (as defined in the employment agreement) or upon a change in control (as defined 
in the employment agreement), Mr. Pandya would be entitled to receive any earned but unpaid base salary, bonus and 
benefits in an amount equal to six months of his annual base salary at the time of such termination plus one week for 
every fully completed year of service, up to one year.  In addition, Mr. Pandya’s outstanding but unvested restricted 
stock and stock options would vest immediately.   

Compensation of Chief Financial Officer 

On December 15, 2005, we entered into a three-year employment agreement with Mark Westgate, pursuant to 
which he serves as our Vice President.  During his employment, Mr. Westgate was to receive an annual base salary of 
$160,000, and was to be eligible to earn an annual bonus up to 50% of his annual base salary based upon the 
achievement by the Company of objective performance measures established and determined at the beginning of each 
fiscal year by the Board of Directors or its Executive Compensation Committee in consultation with Ms. Liu and Mr. 
Westgate.   On January 1, 2008, the base annual salary of Mr. Westgate was adjusted to $235,000 for several reasons: 
the progress that NexMed made during 2007, Mr. Westgate’s accomplishments during 2007, and the fact that Mr. 
Westgate’s salary was not deemed to be comparable to industry standards according to data supplied by ORC 
Worldwide Compensation Consultants.  On December 15, 2008, Mr. Westgate’s employment agreement automatically 
renewed for a one-year period. 

Mr. Westgate’s employment agreement provides for grants of options to purchase shares of our Common 
Stock under the Stock Plan.  These options are intended to be incentive stock options to the fullest extent permitted 
under the Internal Revenue Code.  In December 2005, Mr. Westgate received a total of 75,000 stock options vesting in 
three equal installments on December 31, 2006, 2007 and 2008.   

Mr. Westgate’s employment agreement also provides for grants of Common Stock under the 2006 Plan.  In 

January 2007, Mr. Westgate was awarded a restricted stock grant of 75,000 shares.  The award vests in three equal 
installments of 25,000 shares on each December 31, 2007, 2008 and 2009.  This award was intended to retain Mr. 
Westgate in his position as CFO, to recognize the progress made by the Company in 2006, to acknowledge Mr. 
Westgate’s contributions towards that progress, and to remain competitive with industry compensation standards.  

Additionally, in 2008 the Board approved performance-based stock grants to the three named executives, 

including Mr. Westgate, which vest in two equal installments upon the re-submission of the NDA for Vitaros® and upon 
the FDA’s approval of the NDA.  Mr. Westgate’s award is 100,000 shares of Common Stock.   As discussed in Note 3 

60

 
 
 
 
 
 
 
 
 
 
 
  
 
 
of the Consolidated Financial Statements in Part II, Item 8, the U.S. rights to Vitaros®  were sold to Warner and the 
FDA approval of Vitaros® is now the responsibility of Warner. 

The number of shares awarded in the above mentioned stock option grants and restricted Common Stock 

grants was determined such that Mr. Westgate would eventually achieve an ownership percentage approaching 1% of 
the Company as CFO.  The Executive Compensation Committee determined, based on their analysis of competitive 
market data compiled by the director of human resources, that our named executive officers, other than our CEO, 
should have a total equity compensation package in order to achieve such ownership percentage.  Accordingly, on 
October 3, 2008 the Executive Compensation Committee approved a grant of 500,000 shares vesting in two equal 
installments on June 30, 2009 and 2010.  This new grant in 2008 brought Mr. Westgate’s ownership percentage (vested 
and unvested) as of December 31, 2008 to approximately 0.9%. 

Mr. Westgate’s employment agreement provided that, in the event of termination of his employment for 

“Cause” (as defined in the employment agreement), or death and disability, Mr. Westgate would be entitled to receive 
any earned but unpaid base salary, bonus and benefits.  In the event of the termination of Mr. Westgate’s employment 
without Cause, by him with “Good Reason” (as defined in the employment agreement) or upon a change in control (as 
defined in the employment agreement), Mr. Westgate would be entitled to receive any earned but unpaid base salary, 
bonus and benefits in an amount equal to six months of his annual base salary at the time of such termination plus an 
additional week of base salary for every fully-completed year of service, for a total salary continuation period not to 
exceed one year.  In addition, Mr. Westgate’s outstanding but unvested stock and stock options would vest 
immediately.   

Executive Compensation Committee Report 

The Executive Compensation Committee evaluates and establishes compensation for executive officers and is 

responsible for determining the recipients and the size of awards under the 2006 Plan.  The Executive Compensation 
Committee has reviewed and discussed with management the Compensation Discussion and Analysis found in this 
Form 10-K.   The Executive Compensation Committee is satisfied that the Compensation Discussion and Analysis 
fairly and completely represents the philosophy, intent, and actions of the Committee with regard to executive 
compensation.  We recommended to the Board of Directors that the Compensation Discussion and Analysis be included 
in this Form 10-K for filing with the Securities and Exchange Commission. 

The Executive Compensation Committee of the Board of Directors 

Arthur D. Emil, Esq. 
David S. Tierney, MD 
Martin R. Wade, III, Chairman 

61

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Summary Compensation Table for 2008, 2007 and 2006 

As discussed above in our Compensation Discussion and Analysis, our executives under employment 
agreements received base salary, bonuses, stock option awards and stock grants in 2008, 2007 and 2006.  The following 
table sets forth the compensation paid by NexMed during the years ended December 31, 2008, 2007 and 2006 to the   
individuals listed who were serving as executive officers at the end of our last fiscal year (collectively, the “Named 
Executive Officers”): 

Name and 
Principal 
Position 

Year 

Salary 
($) 

Bonus 
($) 
(2) 

Stock 
Awards 
($) 
(1) 

Option 
Awards 
($) 
(1) 

All Other 
Compen-
sation ($) 

Total ($) 

(a) 

(b) 

(c) 

Vivian H. 
Liu, CEO  (3) 

2008 

$300,000 

(d) 

$-- 

2007 

$273,207 

$150,000 

2006 

$200,000 

$125,000 

2008 

$225,000 

$-- 

2007 

2006 

$32,903 
(5) 
$-- 

$18,500 
(5) 
$-- 

2008  

$235,000 

$-- 

2007 

$198,681 

$100,000 

2006 

$160,000 

$80,000 

Hemanshu 
Pandya, 
COO 

Mark 
Westgate, 
CFO 

(e) 

(f) 

(i) 

(j) 

$650,248 
(4) 

$210,000 
(4) 
$124,000 

$46,451 
(6) 
$8,696  
(6) 
$-- 

$36,419 
(8) 
$25,000 
(8) 
$31,000 

$36,512 

$80,670 

$71,162 

$63,232 
(7) 
$15,808 
(7) 
$-- 

$14,913  

$49,446 

$41,293  

$4,835 
(9) 

$7,325 
(9) 
$7,099 
(9) 

$2,631 
(10) 
$41  
(10) 
$-- 

$3,542 
(11) 
$6,425 
(11) 
$6,995 
(11) 

$991,595 

$713,877 

$520,162 

$337,314 

$75,907 

$-- 

$289,874 

$373,127 

$312,923 

1.  Market values for stock awards were determined by multiplying the number of shares granted by the closing market 

price of the Company’s stock on the grant date in accordance with SFAS 123R.  Stock-based compensation under 
SFAS 123R is recognized as an expense on a straight-line basis over the required service period of the entire award 
(generally the vesting period of the award).  The value of stock option awards was calculated using the Black-
Scholes method in accordance with SFAS 123R. A discussion of the assumptions used in calculating the Black-
Scholes values may be found in Note 2 and Note 9 of the Consolidated Financial Statements in Part II, Item 8.   
2.  There were no 2008 bonuses accrued or paid.  2007 bonuses were accrued in 2007 and paid on March 14, 2008.  

2006 bonuses were paid in December 2006.  

3.  Ms. Liu served as COO from January 2006 through June 18, 2007 at which time she was appointed CEO.     
4.  Ms. Liu was granted 100,000 shares of restricted stock in August 2008.  The shares vest in two equal installments 
upon the re-submission of the NDA for Vitaros® and upon the FDA’s approval of the NDA.  There is no expense 
recorded for this grant in 2008 as the vesting is contingent upon an event that is uncertain.  Ms. Liu was granted 
850,000 shares of restricted stock which were awarded when she was appointed CEO in June 2007. The shares vest 
in four installments, the first installment of 100,000 shares vested on October 3, 2007 upon the signing of her 
employment agreement with the remaining 750,000 shares vesting in three equal installments of 250,000 shares on 
June 18, 2008, 2009 and 2010, respectively.  Ms. Liu also received a grant of 150,000 shares of restricted stock in 
January 2007 as compensation for her services as COO.  The shares vest in three equal installments of 50,000 
shares on each December 31, 2007, 2008, and 2009. 

5.  Mr. Pandya’s salary and bonus for 2007 were pro-rated for two months of employment in 2007.   

62

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
6.  On October 3, 2008 Mr. Pandya was granted 500,000 shares of restricted stock which vest in two equal installments 

on June 30, 2009 and 2010.  Mr. Pandya was also granted 100,000 shares of restricted stock in August 2008.  The 
shares vest in two equal installments upon the re-submission of the NDA for Vitaros® and upon the FDA’s approval 
of the NDA.  There is no expense recorded for this grant in 2008 as the vesting is contingent upon an event that is 
uncertain.  On October 31, 2007 Mr. Pandya was granted 125,000 shares of restricted stock. 75,000 shares will vest 
in three equal installments of 25,000 shares each on October 31, 2008, 2009 and 2010.  The remaining 50,000 
shares vest upon the execution of a licensing/development agreement brought to the Company by Mr. Pandya 
valued at over $5 million on or before April 30, 2009.  In accordance with SFAS 123R, compensation expense for 
the 50,000 shares will be recorded for the quarter ended March 31, 2009 when these shares vested upon the 
completion of the business transaction as stated above. 

7.  On October 31, 2007, Mr. Pandya was granted an option to purchase a total of 175,000 shares of our Common 

Stock at $1.43 per share, the market price of our Common Stock at the time of the grant. The award vests in three 
installments of 25,000 options on October 31, 2008, 50,000 options on October 31, 2009 and 100,000 options on 
October 31, 2010. 

8.  On October 3, 2008 Mr. Westgate was granted 500,000 shares of restricted stock which vest in two equal 

installments on June 30, 2009 and 2010.  Mr. Westgate was also granted 100,000 shares of restricted stock in 
August 2008.  The shares vest in two equal installments upon the re-submission of the NDA for Vitaros® and upon 
the FDA’s approval of the NDA.  There is no expense recorded for this grant in 2008 as the vesting is contingent 
upon an event that is uncertain.  Mr. Westgate received a grant of 75,000 shares of restricted stock in January 2007. 
The shares vest in three equal installments of 25,000 shares on each of December 31, 2007, 2008, and 2009. 
9.  This amount includes the Company’s matching and profit sharing contribution to the 401k plan of $4,385, $6,750 
and $6,600 in 2008, 2007 and 2006, respectively and life insurance premiums paid on behalf of the Named 
Executive of $450, $575 and $499 in 2008, 2007 and 2006, respectively as part of the employee benefit plan for all 
employees, whereby each employee has a Company paid life insurance policy in the amount of each employee’s 
annual salary.  

10.  This amount includes the Company’s matching and profit sharing contribution to the 401k plan of $2,441 and $0 in 

2008 and 2007, respectively and life insurance premiums paid on behalf of the Named Executive of $190 and $41 
in 2008 and 2007, respectively as part of the employee benefit plan for all employees, whereby each employee has 
a Company paid life insurance policy in the amount of each employee’s annual salary. 

11.  This amount includes the Company’s matching and profit sharing contribution to the 401k plan of $3,342, $5,977 
and $6,600 in 2008, 2007 and 2006, respectively and life insurance premiums paid on behalf of the Named 
Executive of $200, $448 and $395 in 2008, 2007 and 2006, respectively as part of the employee benefit plan for all 
employees, whereby each employee has a Company paid life insurance policy in the amount of each employee’s 
annual salary. 

GRANTS OF PLAN BASED AWARDS FOR 2008 

The compensation plans under which the grants in the following table were made are generally described in 

the Compensation Discussion and Analysis above: 

63

 
 
 
 
 
 
 
 
Name

Grant Date

Estimated 
Future Payouts 
Under Equity 
Incentive  Plan 
Awards (Target 
shares)

(b)
8/12/2008

(g)
100,000 (2)

All Other 
Stock 
Awards:  
Number of 
Shares of 
Stock or 
Units

(i)

8/12/2008

100,000 (2)

10/3/2008

500,000

(a)
Vivian H. Liu, 
CEO

Hemanshu 
Pandya, COO

Mark Westgate, 
CFO

8/12/2008

100,000 (2)

10/3/2008

500,000

Grant Date 
Fair Value of 
Equity Aw ards 
(1)

(l)
$147,000 

$147,000 

$75,000 

$147,000 

$75,000 

(1)  Market values for stock awards were determined by multiplying the number of shares granted by the closing market price 

of our stock on the grant date in accordance with SFAS 123R.   

(2)  Represents shares of restricted stock which vest in two equal installments upon re-submission of the NDA for Vitaros® and 

upon FDA approval of the NDA. 

OUTSTANDING EQUITY AWARDS AT DECEMBER 31, 2008 

Options are granted at 100 percent of fair market value on the date of the grant; they usually vest in three equal 

installments over a three year period.  More discussion of our equity compensation programs can be found in the 
Compensation Discussion and Analysis.  There are no unexercised, unearned options under an equity incentive plan.   

Option Awards 

Name 

Number of 
Securities 
Underlying 
Unexercised 
Options 
(#) 
Exercisable 

Number of 
Securities 
Underlying 
Unexercised 
Options  
(#) 
Unexercisable 

Option Exercise 
Price 
($) 

Option 
Expiration 
Date 

Number of 
Shares or 
Units of 
Stock That 
Have Not 
Vested (#) 

Stock Awards 

Market 
Value of 
Shares or 
Units of 
Stock 
That 
Have Not 
Vested 
($) 
(1) 

Equity 
Incentive 
Plan 
Awards: 
Number of 
Unearned 
Shares, 
Units or 
Other 
Rights 
That Have 
Not Vested 
(#) 

Equity 
Incentive 
Plan 
Awards: 
Market or 
Payout 
Value of 
Unearned 
Shares, 
Units or 
Other 
Rights 
That Have 
Not 
Vested 
($) 
(1) 

(a) 

(b) 

Vivian H. 
Liu, CEO 

180,000 (3) 

105,000 (4) 

114,284 (5) 

90,000 (6) 

(c) 

-- 

-- 

-- 

-- 

(e) 

$0.92 

$0.70 

$0.55 

$4.00 

(f) 

(g) 

(h) 

(i) 

(j) 

12/15/15 

12/16/12 

12/3/12 

1/19/10 

64

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Hemanshu 
Pandya, 
COO 

Mark 
Westgate, 
CFO 

100,000 (7) 

-- 

$0.81 

8/3/16 

25,000 

150,000 (10) 

$1.43 

10/31/17 

75,000 (3) 

5,000 (12) 

27,273 (5) 

15,000 (13) 

80,000 (8) 

-- 

-- 

-- 

-- 

$0.92 

$1.32 

$0.55 

$3.25 

$0.81 

12/15/15 

1/18/15 

12/3/12 

3/11/12 

8/3/16 

550,000 (8) 

$841,500 

100,000 (9) 

$147,000 

50,000 (2) 

$71,500 

100,000 (9) 

$147,000 

50,000 (11) 

$71,500 

500,000 (15) 

$75,000 

100,000 (9) 

$147,000 

500,000 (15) 

$50,000  

25,000 (14) 

$25,000 

(1)  Market values were determined by multiplying the number of shares granted by the closing market price of our Common 

Stock on the grant date. 

(2)  Stock vests and restrictions lapse only upon the execution of a licensing/development agreement brought to the Company 
by Mr. Pandya valued at over $5 million on or before April 30, 2009.  These shares vested on February 3, 2009 when 
Warner purchased the U.S. rights to Vitaros®.  

(3)  Options vested in three equal installments on December 31, 2006, 2007 and 2008. 
(4)  Options vested in three equal installments on December 31, 2003, 2004 and 2005. 
(5)  Options vested on July 1, 2003. 
(6)  Options vested in three equal installments on January 19, 2001, 2002 and 2003. 
(7)  Options vested in two equal installments on the filing of the NDA for our Vitaros® in September 2007 and the acceptance 

of the NDA for review by the FDA in November 2007. 

(8)  Shares vest in two equal installments of 250,000 shares on June 18, 2009 and 2010.  50,000 shares vest in on December 31, 

2009. 

(9)  The stock vests in two equal installments upon the re-submission of the NDA for Vitaros® and upon the FDA’s approval of 

the NDA.  

(10) The option award vests in two installments of 50,000 options on October 31, 2009 and 100,000 options on October 31, 

2010. 

(11) The award vests in two equal installments of 25,000 shares each on October 31, 2009 and 2010. 
(12) Options vested on the grant date of January 18, 2005. 
(13) Options vested in three equal installments on March 11, 2003, 2004 and 2005. 
(14) The award vests on December 31, 2009. 
(15) The award vests in two equal installments on June 30, 2009 and 2010. 

OPTION EXERCISES AND STOCK VESTED FOR 2008 

No stock options were exercised by the Named Executive Officers during 2008.  

The following table indicates restricted stock vested in 2008 for the Named Executives: 

Name and 
Principal 
Position 

Date of 
Vesting 

Number 
of Shares 
Acquired 
on 
Vesting 

Value 
Realized on 
Vesting 
($) 
(1) 

65

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(#) 

Vivian H. 
Liu, CEO  

Hemanshu 
Pandya, 
COO 

Mark 
Westgate, 
CFO 

6/18/08 

250,000 

$370,000 

12/31/08 

50,000 

$7,000 

10/31/08 

25,000 

$3,000 

12/31/08 

25,000 

$3,500 

(1)  Market values were determined by multiplying the number of shares vesting by the closing market price of our Common 

Stock on the vesting date. 

POTENTIAL PAYMENTS UPON TERMINATION OR CHANGE-IN-CONTROL AT DECEMBER 31, 2008 

The table below sets forth the estimated current value of payments and benefits to each of the Named  

Executive Officers upon a change of control, a qualifying termination, or resignation for good reason of the Named 
Executive Officer, in each case as defined within the employment agreement for the Named Executive attached as 
Exhibits  10.21, 10.22, 10.30 and 10.35.  All payments are conditioned upon and subject to the named Executive's first 
executing a Confidential Separation Agreement including a general waiver and release (and the expiration of any 
associated revocation period), in such reasonable and customary form as shall be prepared by the Company, of all 
claims the Named Executive may have against the Company, and related entities and individuals.   

The value of accelerated equity awards shown in the table below was calculated using the closing price of our 

Common Stock on December 31, 2008 ($0.14).  The value of the options is the aggregate spreads between $0.14 and 
the exercise prices of the accelerated options; if less than $0 then the value of the accelerated options is zero.  

Name and 
Principal 
Position 

Lump 
Sum 
Cash 
Payment 
(1) 

Value of 
accelerated 
stock 
options 

Value of 
accelerated 
restricted 
stock 

Total ($) 

Vivian H. 
Liu, CEO  

Hemanshu 
Pandya, 
COO 

$300,000 

$0 

$91,000 

$391,000 

$116,827 

$0 

$91,000 

$207,827 

66

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Name and 
Principal 
Position 

Lump 
Sum 
Cash 
Payment 
(1) 

Value of 
accelerated 
stock 
options 

Value of 
accelerated 
restricted 
stock 

Total ($) 

Mark 
Westgate, 
CFO 

$149,135 

$0 

$87,500 

$236,635 

(1)  Lump sum cash payments are based on the amount of salary payable at December 31, 2008 per the Named Executives’ 

employment agreements based on service through such date.  In the case of Ms. Liu, the amount is equivalent to one year’s 
salary.  In the case of Mr. Pandya and Mr. Westgate, the amount is equivalent to six month’s salary plus an additional week 
of base salary for each fully-completed year of service (at December 31, 2008, seven weeks for Mr. Westgate and one 
week for Mr. Pandya). 

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION 

  Arthur D. Emil, David S. Tierney and Martin R. Wade, III served on the Executive Compensation Committee 
in 2008.  None of these three directors has ever been an employee of NexMed or its subsidiaries.  No NexMed executive 
officer served as a member of the Board of Directors or the Executive Compensation Committee of any company whose 
executive officers included a member of our Board of Directors or Executive Compensation Committee. 

ITEM 12. 

SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT 
AND RELATED STOCKHOLDER MATTERS. 

EQUITY COMPENSATION PLAN INFORMATION 

The following table gives information as of December 31, 2008, about shares of our Common Stock that may be issued 
upon the exercise of options, warrants and rights under all of our existing equity compensation plans (together, the 
"Equity Plans"): 

Plan category  

Equity compensation 
plans approved by 
security holders  
Equity compensation 
plans not approved by 
security holders  
Total  

(a)  
Number of securities to 
be issued upon exercise 
of outstanding options, 
warrants and rights  

(b)  
Weighted-average 
exercise price of 
outstanding options, 
warrants and rights  

(c)  
Number of securities remaining available 
for future issuance under equity 
compensation plans (excluding securities 
reflected in column (a))  

3,368,991(1) 

$1.40 

373,203(2) 

3,368,991 

$1.40 

373,203 

(1) Consists of options outstanding at December 31, 2008 under The NexMed Inc. Stock Option and Long Term 
Incentive Plan (the "Incentive Plan") and The NexMed, Inc. 2006 Stock Incentive Plan (the "2006 Plan"). 

(2) Consists of zero and 373,203 shares of Common Stock that remain available for future issuance, at December 31, 
2008, under the Incentive Plan and 2006 Plan, respectively.  

67

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
The following table sets forth information with respect to the beneficial ownership, as of February 27, 2009, of 
Common Stock by (a) each person known by management to be the beneficial owner of more than 5% of our outstanding 
voting securities, (b) our directors and executive officers, individually, and (c) our directors and executive officers as a 
group as of February 27, 2009. 

SECURITY OWNERSHIP TABLE 

Name, Position and Address of Beneficial Owner (1) 

Number of Shares Beneficially Owned (2) 

Vivian H. Liu 
President & Chief Executive Officer (3) 

Hemanshu Pandya (4) 
Vice President & Chief Operating Officer  

Mark Westgate (5) 
Vice President & Chief Financial Officer 

Richard J. Berman 
Chairman of the Board (6) 

Arthur D. Emil, Esq. 
Director (7) 

Leonard A. Oppenheim, Esq.  
Director (8) 

David S. Tierney, MD 
Director (9) 

Martin R. Wade, III 
Director (10) 

Jacob May (11) 
4525 Harding Road 
Nashville, TN 37205 

All Executive Officers and Directors as a Group (eight 
persons) (12) (13) 

* less than 1% 

1,280,284 

100,000 

306,591 

Percent of Class 
(%) 

1.51% 

* 

* 

1,382,413 

1.62% 

431,455 

855,727 

225,824 

269,166 

* 

* 

* 

* 

9,835,530 

11.65% 

4,851,460 

5.56% 

1)  The address for each of the executive officers and directors of the Company is 89 Twin Rivers Drive, East Windsor, New Jersey 

08520.  

Includes 500,000 shares issuable upon exercise of stock options exercisable within 60 days of February 27, 2009 and 10,708 

Includes 140,000 shares issuable upon exercise of stock options exercisable within 60 days of February 27, 2009 and 10,708 

2)  Except as otherwise indicated herein, all shares are solely and directly owned, with sole voting and dispositive power.  
3) 
Includes 589,284 shares issuable upon exercise of stock options exercisable within 60 days of February 27, 2009. 
4) 
Includes 25,000 shares issuable upon exercise of stock options within 60 days of February 27, 2009. 
5) 
Includes 202,273 shares issuable upon exercise of stock options exercisable within 60 days of February 27, 2009. 
6) 
Includes  1,150,000  shares  issuable  upon  exercise  of  stock  options  exercisable  within  60  days  of  February  27,  2009                   
and 20,540 restricted shares that vest within 60 days of February 27, 2009.   
7) 
restricted shares that vest within 60 days of February 27, 2009. 
8) 
restricted shares that vest within 60 days of February 27, 2009. 
9) 
10)  Includes 100,000 shares issuable upon exercise of stock options exercisable within 60 days of February 27, 2009 and 10,708 
restricted shares that vest within 60 days of February 27, 2009. 
11)  Except  for  percentage  information,  this  information  is  based  upon  a  Form  4  filed  with  the  Securities  and  Exchange     
Commission on February 18, 2009.   
12)  Includes 2,681,557 shares issuable upon exercise of stock options exercisable within 60 days of February 27, 2009 and 63,372 
restricted shares that vest within 60 days of February 27, 2009. 
13)  No shares owned by any of our officers and directors were pledged as security. 

Includes 10,708 restricted shares that vest within 60 days of February 27, 2009. 

68

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ITEM 13. 

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR 
INDEPENDENCE. 

Review and Approval of Transactions with Related Persons 

The Board has adopted a written policy and procedures for review, approval and monitoring of transactions 

involving our Company and “related persons” (directors and executive officers or their immediate family members, or 
Stockholders owning 5% or greater of the Company’s outstanding stock).  The policy covers any related person 
transaction that meets the minimum threshold for disclosure in our proxy statement under the relevant SEC rules 
(generally transactions involving amounts exceeding $120,000 in which a related person has a direct or indirect material 
interest).  Related person transactions must be approved by the Board or by the Audit Committee of the Board 
consisting solely of independent directors, which will approve the transaction if they determine that it is in our best 
interests.  The Board or Audit Committee will periodically monitor the transaction to ensure that there are no changes 
that would render it advisable for us to amend or terminate the transaction. 

There were no related person transactions entered into in 2008 and there are no related person arrangements in 

place from previous years and no proposed related person transaction.  

Director Independence 

During the year ended December 31, 2008, the Board of Directors has determined that each of Mr. Emil, Mr. 
Oppenheim, Dr. Tierney and Mr. Wade met the definition of independence under the NASDAQ Capital Market listing 
requirements. 

ITEM 14.           PRINCIPAL ACCOUNTANT FEES AND SERVICES. 

Audit Fees 

The aggregate fees billed or to be billed by Amper, Politziner & Mattia, LLP for 2008 were $186,000 and 

$279,000 for 2007. 

Audit-related Fees 

 There were no fees billed or to be billed by Amper, Politziner & Mattia,LLP for each of the last two fiscal 
years for assurance and related services that were reasonably related to the performance of the audit or review of our 
financial statements and that are not reported under “Audit Fees” above. 

Tax Fees 

We retain the services of PricewaterhouseCoopers LLP as our tax advisor.  The aggregate fees billed by 

PricewaterhouseCoopers LLP in each of the last two fiscal years for professional services rendered for tax compliance, 
tax advice and tax planning were $30,000 for 2008 and $28,000 for 2007.  The nature of the services performed for 
these fees included the preparation of our federal and state tax returns.   

All Other Fees 

There were no other fees billed to us by Amper, Politznier & Mattia, LLP or PricewaterhouseCoopers LLP 

during 2008 and 2007. 

Pre-Approval Policies and Procedures 

It is our policy that all services provided by Amper, Politziner & Mattia, LLP shall be pre-approved by the Audit 
Committee. Amper, Politziner & Mattia, LLP provides the Audit Committee with an engagement letter during the first 
quarter of each fiscal year outlining the scope of the audit services proposed to be performed during the fiscal year and 
the estimated fees for such services.  Pre-approval of audit and permitted non-audit services may be given by the Audit 

69

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Committee at any time up to one year before the commencement of such services by Amper, Politziner & Mattia, 
LLP.  Pre-approval must be detailed as to the particular services to be provided. Pre-approval may be given for a 
category of services, provided that (i) the category is narrow enough and detailed enough that management will not be 
called upon to make a judgment as to whether a particular proposed service by Amper, Politziner & Mattia, LLP fits 
within such pre-approved category of services and (ii) the Audit Committee also establishes a limit on the fees for 
such pre-approved category of services.   The Chairman of the Audit Committee has, and the Audit Committee may 
delegate to any other member of the Audit Committee, the authority to grant pre-approval of permitted non-audit 
services to be provided by Amper, Politziner & Mattia, LLP between Audit Committee meetings; provided, however, 
that any such pre-approval shall be presented to the full Audit Committee at its next scheduled meeting. The Audit 
Committee pre-approved all audit and permitted non-audit services that were provided in 2008 and 2007.   

PART IV. 

ITEM 15. 

EXHIBITS AND FINANCIAL STATEMENT SCHEDULES.  

(a) 

1.   

Financial Statements: 

The information required by this item is included in Item 8 of Part II of this Form 10-K.  

2. 

Financial Statement Schedules 

Report  of  Independent  Registered Public  Accounting  Firm  on  Financial  Statement  Schedule  for  the 
years ended December 31, 2008, 2007 and 2006. 

SCHEDULE II 

NEXMED, INC. 
SCHEDULE OF VALUATION AND QUALIFYING ACCOUNTS 

Description 

Balance at 
Beginning 
of Year 

Charged to 
Costs and  
Expenses 

Charged 
to 
Other  
Accounts 

Deductions 

Balance at 
End of Year 

Year ended December 31, 2008 
       Valuation allowance - deferred tax asset       $39,274,127      $3,561,172 

  -- 

           --              $42,835,299 

Year ended December 31, 2007       
       Valuation allowance – deferred tax asset       $35,642,110       $3,632,017        --                        --           $39,274,127 

Year ended December 31, 2006 
       Valuation allowance - deferred tax asset       $32,859,672       $3,682,438 

   -- 

              --           $35,642,110  

All other schedules have been omitted because the information is not applicable or is presented in the 
Financial Statements or Notes thereto. 

3. 

Exhibits   

EXHIBITS  
NO. 

DESCRIPTION 

3.1 

Amended and Restated Articles of Incorporation of the Company (incorporated herein by 

70

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
                                                              
 
 
 
 
 
 
3.2 

3.3 

3.4 

3.5 

4.1 

4.2  

4.3 

4.4 

4.5 

4.6 

4.7 

4.8 

4.9 

4.10 

4.11 

reference to Exhibit 2.1 filed with the Company's Form 10-SB filed with the Securities and 
Exchange Commission on March 14, 1997). 

Amended and Restated By-laws of the Company (incorporated herein by reference to Exhibit 3.1 
to the Company’s Form 10-Q filed with the Securities and Exchange Commission on May 14, 
2003). 

Certificate of Amendment to Articles of Incorporation of the Company, dated June 22, 2000 
(incorporated herein by reference to Exhibit 3.2 to the Company’s Form 10-K filed with the 
Securities and Exchange Commission on March 31, 2003). 

Certificate of Amendment to the Company’s Articles of Incorporation, dated June 14, 2005. 
(incorporated herein by reference to Exhibit 3.4 to the Company’s Form 10-K filed with the 
Securities and Exchange Commission on March 16, 2006). 

Second Amended and Restated By-Laws of the Company, effective as of April 18, 2008 
(incorporated herein by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K 
filed with the Securities and Exchange Commission on April 24, 2008). 

Form of Common Stock Certificate (incorporated herein by reference to Exhibit 3.1 filed with the 
Company's Form 10-SB filed with the Securities and Exchange Commission on March 14, 1997). 

Rights Agreement and form of Rights Certificate (incorporated herein by reference to Exhibit 4 
to the Company’s Current Report on Form 8-K filed with the Commission on April 10, 2000). 

Certificate of Designation of Series A Junior Participating Preferred Stock (incorporated herein 
by reference to Exhibit 4 to the Company’s Current Report on Form 8-K filed with the 
Commission on April 10, 2000). 

Form of Warrant dated April 21, 2003 (incorporated herein by reference to Exhibit 4.2 to the 
Company’s Form 10-Q filed with the Securities and Exchange Commission on May 14, 2003). 

Form of Common Stock Purchase Warrant dated July 2, 2003 (incorporated herein by reference 
to Exhibit 4.3 to the Company’s Registration Statement on Form S-3 filed with the Securities and 
Exchange Commission on July 17, 2003). 

Form of Warrant dated June 18, 2004 (incorporated herein by reference to Exhibit 4.1 to the 
Company’s Form 8-K filed with the Securities and Exchange Commission on June 25, 2004). 

Form of Common Stock Purchase Warrant A, dated December 17, 2004 (incorporated herein by 
reference to Exhibit 4.1 to the Company’s Current Report on Form 8-K filed with the Securities 
and Exchange Commission on December 23, 2004). 

Form of Warrant, dated May 17, 2005 (incorporated herein by reference to Exhibit 4.1 to the 
Company’s Current Report on Form 8-K filed with the Securities and Exchange Commission on 
May 19, 2005). 

Form of Warrant, dated January 23, 2006 (incorporated herein by reference to Exhibit 4.1 to the 
Company’s Current Report on Form 8-K filed with the Securities and Exchange Commission on 
January 27, 2006). 

Form of Warrant, dated November 30, 2006 (incorporated herein by reference to Exhibit 4.1 to 
the Company’s Form 8-K filed with the Securities and Exchange Commission on December 4, 
2006). 

Form of Warrant, dated December 20, 2006 (incorporated herein by reference to Exhibit 4.1 to 
the Company’s Form 8-K filed with the Securities and Exchange Commission on December 21, 

71

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
4.12 

4.13 

4.14 

10.1* 

10.2* 

10.3 

10.4* 

10.5* 

10.6 

10.7 

10.8 

10.9* 

10.10 

2006). 

Amendment No. 1 to Rights Agreement, dated as of January 16, 2007 (incorporated herein by 
reference to Exhibit 4.1 to the Company’s Form 8-K filed with the Securities and Exchange 
Commission on January 22, 2007). 

Form of Warrant, dated October 26, 2007 (incorporated herein by reference to Exhibit 4.1 to the 
Company’s Current Report on Form 8-K filed with the Securities and Exchange Commission on 
October 31, 2007). 

Form of Warrant (incorporated herein by reference to Exhibit 4.4 to the Company’s Current 
Report on Form 8-K filed with the Securities and Exchange Commission on July 29, 2008). 

Amended and Restated NexMed, Inc. Stock Option and Long-Term Incentive Compensation 
Plan (incorporated herein by reference to Exhibit 10.1 filed with the Company's Form 10-Q filed 
with the Securities and Exchange Commission on May 15, 2001).  

The NexMed, Inc. Recognition and Retention Stock Incentive Plan (incorporated herein by 
reference to Exhibit 99.1 filed with the Company's Form 8-K filed with the Securities and 
Exchange Commission on May 28, 2004). 

License Agreement dated March 22, 1999 between NexMed International Limited and 
Vergemont International Limited  (incorporated herein by reference to Exhibit 10.7 of the 
Company’s Form 10-KSB filed with the Securities and Exchange Commission on March 16, 
2000).   

The NexMed, Inc. Non-Qualified Stock Option Plan (incorporated herein by reference to Exhibit 
6.6 filed with the Company's Form 10-SB/A filed with the Securities and Exchange Commission 
on June 5, 1997). 

Employment Agreement dated February 26, 2002 by and between NexMed, Inc. and Dr. Y.   
Joseph Mo (incorporated herein by reference to Exhibit 10.7 of the Company's Form 10-K filed 
with the Securities and Exchange Commission on March 29, 2002). 

Registration Rights Agreement between the Company and The Tailwind Fund Ltd. and Solomon 
Strategic Holdings, Inc. dated June 11, 2002 (incorporated herein by reference to Exhibit 10.2 to 
the Company's Form 10-Q filed with the Securities and Exchange Commission on August 14, 
2002). 

Investor Rights Agreement, dated as of April 21, 2003, between the Company and the Purchasers 
identified on Schedule 1 to the Investor Rights Agreement (incorporated herein by reference to 
Exhibit 10.2 to the Company’s Form 10-Q filed with the Securities and Exchange Commission 
on May 14, 2003). 

Investor Rights Agreement, dated as of July 2, 2003, between the Company and the Purchasers       
identified on Schedule 1 to the Investor Rights Agreement (incorporated herein by reference to 
Exhibit 10.2 to the Company’s Registration Statement on Form S-3 filed with the Securities and 
Exchange Commission on July 17, 2003). 

Amendment dated September 26, 2003 to Employment Agreement by and between Dr. Y. Joseph 
Mo and NexMed, Inc. dated February 26, 2002 (incorporated herein by reference to Exhibit 10.4 
to the Company's Form 10-Q filed with the Securities and Exchange Commission on November 
12, 2003). 

Registration Rights Agreement, dated as of December 12, 2003, between the Company and the 
Purchasers named therein (incorporated herein by reference to Exhibit 10.2 to the Company’s 
Registration Statement on Form S-3 filed with the Securities and Exchange Commission on 

72

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
10.11 

10.12 

10.13* 

10.14* 

10.15 

10.16 

10.17 

10.18+ 

10.19 

10.20 

10.21* 

10.22* 

January 13, 2004).  

Form of 5% Convertible Note due May 31, 2007 (incorporated herein by reference to Exhibit 
10.3 to the Company’s Registration Statement on Form S-3 filed with the Securities and 
Exchange Commission on January 13, 2004). 

Investor Rights Agreement, dated as of June 18, 2004, between the Company and the Purchasers 
identified on Schedule 1 thereto (incorporated herein by reference to Exhibit 10.2 to the 
Company’s Form 8-K filed with the Securities and Exchange Commission on June 25, 2004). 

Stock Option Grant Agreement between the Company and Leonard A. Oppenheim dated 
November 1, 2004 (incorporated herein by reference to Exhibit 10.2 to the Company’s Form 10-
Q filed with the Securities and Exchange Commission on November 9, 2004). 

Form of Stock Option Grant Agreement between the Company and its Directors (incorporated 
herein by reference to Exhibit 10.29 to the Company’s Form 10-K filed with the Securities and 
Exchange Commission on March 16, 2006). 

Investor Rights Agreement, dated as of December 17, 2004, between the Company and the 
Purchasers named therein (incorporated herein by reference to Exhibit 10.2 to the Company’s 
Current Report on Form 8-K filed with the Securities and Exchange Commission on December 
23, 2004). 

Preferred Stock and Warrant Purchase Agreement, dated as of May 16, 2005, between the 
Company and the Purchasers named therein (incorporated herein by reference to Exhibit 10.1 to 
the Company’s Current Report on Form 8-K filed with the Securities and Exchange Commission 
on May 19, 2005). 

Investor Rights Agreement, dated as of May 16, 2005, between the Company and the Purchasers 
named therein (incorporated herein by reference to Exhibit 10.2 to the Company’s Current 
Report on Form 8-K filed with the Securities and Exchange Commission on December 23, 2004). 

License Agreement, dated September 13, 2005, between NexMed, Inc., NexMed International 
Limited and Novartis International Pharmaceutical Ltd. (incorporated herein by reference to 
Exhibit 99.1 to the Company’s Current Report on Form 8-K filed with the Securities and 
Exchange Commission on September 15, 2005). 

Common Stock and Warrant Purchase Agreement, dated as of January 23, 2006, between the 
Company and the Purchasers named therein (incorporated herein by reference to Exhibit 10.1 to 
the Company’s Current Report on Form 8-K filed with the Securities and Exchange Commission 
on January 27, 2006). 

Investor Rights Agreement, dated as of January 23, 2006, between the Company and the 
Purchasers named therein (incorporated herein by reference to Exhibit 10.2 to the Company’s 
Current Report on Form 8-K filed with the Securities and Exchange Commission on January 27, 
2006). 

Employment Agreement dated December 21, 2005 by and between NexMed, Inc. and Vivian H. 
Liu (incorporated herein by reference to Exhibit 10.30 to the Company’s Form 10-K filed with 
the Securities and Exchange Commission on March 16, 2006). 

Employment Agreement dated December 21, 2005 by and between NexMed, Inc. and Mark 
Westgate (incorporated herein by reference to Exhibit 10.31 to the Company’s Form 10-K filed 
with the Securities and Exchange Commission on March 16, 2006). 

10.23 

Common Stock and Warrant Purchase Agreement, dated January 23, 2006 (incorporated herein 
by reference to Exhibit 10.1 to the Company’s Form 8-K filed with the Securities and Exchange 

73

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
10.24* 

10.25 

10.26 

10.27 

10.28 

10.29 

10.30 * 

10.31 + 

10.32 

10.33 

10.34 

10.35 * 

10.36 

Commission on January 27, 2006). 

NexMed, Inc. 2006 Stock Incentive Plan (incorporated herein by reference to Annex A of the 
Company’s Definitive Proxy Statement filed with the Securities and Exchange Commission on 
April 6, 2006). 

Securities Purchase Agreement, dated November 30, 2006, between NexMed, Inc., NexMed 
(U.S.A.), Inc. and Metronome LPC 1, Inc. (incorporated herein by reference to Exhibit 10.1 to 
the Company’s Form 8-K filed with the Securities and Exchange Commission on December 4, 
2006). 

Senior Secured Note, dated November 30, 2006, in favor of Metronome LPC 1, Inc. 
(incorporated herein by reference to Exhibit 10.2 to the Company’s Form 8-K filed with the 
Securities and Exchange Commission on December 4, 2006). 

Common Stock and Warrant Purchase Agreement, dated December 20, 2006 (incorporated 
herein by reference to Exhibit 10.1 to the Company’s Form 8-K filed with the Securities and 
Exchange Commission on December 21, 2006). 

Registration Rights Agreement, dated December 20, 2006 (incorporated herein by reference to 
Exhibit 10.2 to the Company’s Form 8-K filed with the Securities and Exchange Commission on 
December 21, 2006). 

Amendment, effective as of February 13, 2007, to License Agreement between Novartis 
International Pharmaceutical Ltd., NexMed, Inc. and NexMed International Limited, dated 
September 13, 2005 (incorporated herein by reference to Exhibit 99.1 to the Company’s Form 8-
K filed with the Securities and Exchange Commission on February 23, 2007). 

Employment Agreement dated October 31, 2007 between NexMed, Inc. and Hemanshu Pandya 
(incorporated herein by reference to Exhibit 10.1 to the Company’s Form 8-K filed with the 
Securities and Exchange Commission on November 5, 2007). 

License Agreement dated November 1, 2007 between NexMed, Inc. and Warner Chilcott 
Company, Inc (incorporated herein by reference to Exhibit 10.31 to the Company’s Form 10-K 
filed with the Securities and Exchange Commission on March 12, 2008). 

Securities Purchase Agreement, dated October 26, 2007, between NexMed, Inc. and Twin Rivers 
Associates, LLC. (incorporated herein by reference to Exhibit 10.1 to the Company’s Current 
Report 8-K filed with the Securities and Exchange Commission on October 31, 2007). 

Senior Secured Note dated October 26, 2007, between NexMed, Inc. and Twin Rivers 
Associates, LLC. (incorporated herein by reference to Exhibit 10.2 to the Company’s Current 
Report 8-K filed with the Securities and Exchange Commission on October 31, 2007). 

Form of Binding Commitment for Credit Line, dated May 12, 2008 (incorporated herein by 
reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed with the Securities 
and Exchange Commission on May 14, 2008). 

Employment Agreement, dated October 3, 2007, by and between NexMed, Inc. and Vivian H.Liu 
(incorporated herein by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K 
filed with the Securities and Exchange Commission on May 30, 2008). 

Side Letter, effective June 27, 2008, to License Agreement between Novartis International 
Pharmaceutical Ltd., NexMed, Inc. and NexMed International Limited, dated September 13, 
2005 (incorporated herein by reference to Exhibit 10.1 to the Company’s Current Report on Form 
8-K filed with the Securities and Exchange Commission on July 1, 2008). 

74

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
10.37 

10.38 

10.39 

10.40 

10.41 

Form of Purchase Agreement (incorporated herein by reference to Exhibit 10.1 to the Company’s 
Current Report on Form 8-K filed with the Securities and Exchange Commission on July 3, 
2008). 

Form of Note (incorporated herein by reference to Exhibit 10.2 to the Company’s Current Report 
on Form 8-K filed with the Securities and Exchange Commission on July 3, 2008). 

Form of Registration Rights Agreement (incorporated herein by reference to Exhibit 10.3 to the 
Company’s Current Report on Form 8-K filed with the Securities and Exchange Commission on 
July 3, 2008). 

Form of Mortgage, Security Agreement and Assignment of Leases and Rents (incorporated 
herein by reference to Exhibit 10.4 to the Company’s Current Report on Form 8-K filed with the 
Securities and Exchange Commission on July 3, 2008). 

Form of Subsidiary Guaranty (incorporated herein by reference to Exhibit 10.5 to the Company’s 
Current Report on Form 8-K filed with the Securities and Exchange Commission on July 3, 
2008). 

10.42 * 

NexMed, Inc. Amendment to 2006 Stock Incentive Plan (incorporated by reference to Appendix 
A of the Company’s Definitive Proxy Statement filed with the Securities and Exchange 
Commission on April 18, 2008). 

10.43 

10.44 

21 

23.1 

31.1 

31.2 

32.1 

32.2 

Asset Purchase Agreement, dated February 3, 2009, between Warner Chilcott Company, Inc. and 
NexMed, Inc. (incorporated herein by reference to Exhibit 10.1 to the Company’s Current Report 
on Form 8-K filed with the Securities and Exchange Commission on February 5, 2009). 

License Agreement, dated February 3, 2009, between Warner Chilcott Company, Inc. and 
NexMed, Inc. (incorporated herein by reference to Exhibit 10.2 to the Company’s Current Report 
on Form 8-K filed with the Securities and Exchange Commission on February 5, 2009). 

Subsidiaries. 

Consent of Amper, Politziner & Mattia, LLP, independent registered public accounting firm. 

Chief Executive Officer's Certificate, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. 

Chief Financial Officer's Certificate, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. 

Chief Executive Officer's Certificate, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to 
Section 906 of the Sarbanes-Oxley Act of 2002. 

Chief Financial Officer's Certificate, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to 
Section 906 of the Sarbanes-Oxley Act of 2002. 

*Management compensatory plan or arrangement required to be filed as an exhibit pursuant to Item 15(c) of 
Form 10-K.  

+ Portions of this exhibit have been omitted pursuant to a request for confidential treatment with the Securities 
and Exchange Commission. Such portions have been filed separately with the Securities and Exchange 
Commission. 

75

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Pursuant to the requirements of the Section 13 or 15(d) of the Securities Exchange Act of 1934, the Registrant 

has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized. 

SIGNATURES 

NEXMED, INC. 

Dated:  March 12, 2009 

By: 

/s/ Vivian Liu 
Vivian Liu 
President and Chief Executive Officer 

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed 

below by the following persons on behalf of the registrant and in the capacities and on the dates indicated. 

SIGNATURE 

TITLE 

DATE 

/s/ Vivian H. Liu  
VIVIAN H. LIU 

Director, President and Chief Executive Officer               

March 12, 2009 

/s/ Mark Westgate 
MARK WESTGATE 

Vice President, Chief Financial Officer and principal 
accounting officer 

March 12, 2009 

/s/ Richard J. Berman 
RICHARD J. BERMAN 

Chairman of the Board of Directors 

March 12, 2009 

/s/ Arthur D. Emil 
ARTHUR D. EMIL 

Director 

 /s/ Leonard A. Oppenheim 
LEONARD A. OPPENHEIM 

Director 

/s/ David S. Tierney, M.D. 
DAVID S. TIERNEY 

/s/ Martin Wade III 
MARTIN WADE III 

Director 

Director 

March 12, 2009 

         March 12 2009 

March 12, 2009 

March 12, 2009 

76

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Exhibit 21  

SUBSIDIARIES OF NEXMED, INC. 

1.  NexMed Holdings, Inc., incorporated in Delaware on February 28, 1997.   

2.  NexMed (U.S.A.), Inc., incorporated in Delaware on June 18, 1997.   

3.  NexMed International Limited, incorporated in the British Virgin Islands on August 2, 1996.   

   (a)  NexMed International (Hong Kong) Ltd. is a wholly-owned subsidiary of NexMed 
International Limited incorporated in Hong Kong on March 14, 2001.   

77

 
 
 
 
 
 
  
 
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM 

Exhibit 23.1 

To the Board of Directors and Stockholders 
NexMed, Inc.: 

We consent to the incorporation by reference in the Registration Statements on Forms S-3 (Nos. 333-
148060, 333-107137, 333-122114, 333-117717, 333-125565,  333-140110, 333-152591, 333-132611, 333-
111894, 333-1055509, 333-96813, 333-46976, and 333-91957) and Form S-8 (Nos. 333-152284, 333-
138598, and 333-93435) of our report dated March 16, 2009, with respect to the consolidated financial 
statements, schedule, and the effectiveness of internal control over financial reporting of NexMed, Inc. and 
Subsidiaries included in the Annual Report on Form 10-K for the year ended December 31, 2008.  Such 
report includes an uncertainty paragraph with respect to the ability of Nexmed, Inc. to continue as a going 
concern. 

/s/ Amper, Politziner & Mattia, LLP 

Date: March 16, 2009 
Edison, New Jersey 

78

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
I, Vivian H. Liu, certify that:  

CERTIFICATION  

Exhibit 31.1  

1.   I have reviewed this Annual Report on Form 10-K of NexMed, Inc.;  

2.   Based on my knowledge, this report does not contain any untrue statement of a material fact 

or omit to state a material fact necessary to make the statements made, in light of the 
circumstances under which such statements were made, not misleading with respect to the 
period covered by this report;  

3.   Based on my knowledge, the financial statements, and other financial information included in 
this report, fairly present in all material respects the financial condition, results of operations 
and cash flows of the registrant as of, and for, the periods presented in this report;  

4.   The registrant’s other certifying officer and I are responsible for establishing and maintaining 
disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-
15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-
15(f) and 15(d)-15(f)) for the registrant and have:  

(a)  

(b)  

(c)  

(d)  

Designed such disclosure controls and procedures, or caused such 
disclosure controls and procedures to be designed under our 
supervision, to ensure that material information relating to the 
registrant, including its consolidated subsidiaries, is made known to us 
by others within those entities, particularly during the period in which 
this report is being prepared;  

Designed such internal control over financial reporting, or caused such 
internal control over financial reporting to be designed under our 
supervision, to provide reasonable assurance regarding the reliability of 
financial reporting and the preparation of financial statements for 
external purposes in accordance with generally accepted accounting 
principles;  

Evaluated the effectiveness of the registrant’s disclosure controls and 
procedures and presented in this report our conclusions about the 
effectiveness of the disclosure controls and procedures, as of the end of 
the period covered by this report based on such evaluation; and  

Disclosed in this report any changes in the registrant’s internal control 
over financial reporting that occurred during the registrant’s fourth 
fiscal quarter, that has materially affected, or is reasonably likely to 
materially affect, the registrant’s internal control over financial 
reporting; and  

5.   The registrant’s other certifying officer and I have disclosed, based on our most recent 

evaluation of internal control over financial reporting, to the registrant’s auditors and the audit 
committee of the registrant’s board of directors (or persons performing the equivalent 
functions):  

(a)  

All significant deficiencies and material weaknesses in the design or 

79

 
 
 
 
 
 
 
   
   
 
   
   
   
   
   
   
   
   
   
     
   
  
   
  
   
   
   
   
   
   
operation of internal control over financial reporting which are 
reasonably likely to adversely affect the registrant’s ability to record, 
process, summarize and report financial information; and  

(b)  

Any fraud, whether or not material, that involves management or other 
employees who have a significant role in the registrant’s internal 
control over financial reporting.  

Date: March 12, 2009.  

/s/ Vivian H. Liu  
Vivian H. Liu  
Chief Executive Officer  

80

 
 
 
 
 
 
   
   
   
   
   
 
I, Mark Westgate, certify that:  

CERTIFICATION  

Exhibit 31.2  

1.   I have reviewed this Annual Report on Form 10-K of NexMed, Inc.;  

2.   Based on my knowledge, this report does not contain any untrue statement of a material fact 

or omit to state a material fact necessary to make the statements made, in light of the 
circumstances under which such statements were made, not misleading with respect to the 
period covered by this report;  

3.   Based on my knowledge, the financial statements, and other financial information included in 
this report, fairly present in all material respects the financial condition, results of operations 
and cash flows of the registrant as of, and for, the periods presented in this report;  

4.   The registrant’s other certifying officer and I are responsible for establishing and maintaining 
disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-
15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-
15(f) and 15(d)-15(f)) for the registrant and have:  

(a)  

(b)  

(c)  

(d)  

Designed such disclosure controls and procedures, or caused such 
disclosure controls and procedures to be designed under our 
supervision, to ensure that material information relating to the 
registrant, including its consolidated subsidiaries, is made known to us 
by others within those entities, particularly during the period in which 
this report is being prepared;  

Designed such internal control over financial reporting, or caused such 
internal control over financial reporting to be designed under our 
supervision, to provide reasonable assurance regarding the reliability of 
financial reporting and the preparation of financial statements for 
external purposes in accordance with generally accepted accounting 
principles;  

Evaluated the effectiveness of the registrant’s disclosure controls and 
procedures and presented in this report our conclusions about the 
effectiveness of the disclosure controls and procedures, as of the end of 
the period covered by this report based on such evaluation; and  

Disclosed in this report any changes in the registrant’s internal control 
over financial reporting that occurred during the registrant’s fourth 
fiscal quarter, that has materially affected, or is reasonably likely to 
materially affect, the registrant’s internal control over financial 
reporting; and  

5.   The registrant’s other certifying officer and I have disclosed, based on our most recent 

evaluation of internal control over financial reporting, to the registrant’s auditors and the audit 
committee of the registrant’s board of directors (or persons performing the equivalent 
functions):  

(a)   All significant deficiencies and material weaknesses in the design or 

operation of internal control over financial reporting which are reasonably 
likely to adversely affect the registrant’s ability to record, process, 
summarize and report financial information; and  

81

 
 
 
 
 
 
   
 
   
   
   
   
   
   
   
   
   
     
   
 
   
   
   
   
   
   
   
(b)  

Any fraud, whether or not material, that involves management or other 
employees who have a significant role in the registrant’s internal 
control over financial reporting.  

Date: March 12, 2009.  

/s/ Mark Westgate  
Mark Westgate  
Chief Financial Officer  

82

 
 
 
 
 
 
   
   
   
 
   
 
CERTIFICATION OF CHIEF EXECUTIVE OFFICER  
PURSUANT TO  
18 U.S.C. SECTION 1350,  
AS ADOPTED PURSUANT TO  
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002  

Exhibit 32.1  

I, Vivian H. Liu, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the 
Sarbanes-Oxley Act of 2002, that, to my knowledge, the Annual Report of NexMed, Inc. on Form 10-K for 
the year ended December 31, 2008, fully complies with the requirements of Section 13(a) or 15(d) of the 
Securities Exchange Act of 1934 and that information contained in such Annual Report on 10-K fairly 
presents in all material respects the financial condition and results of operations of NexMed, Inc.  

Date: March 12, 2009.  

By: /s/ Vivian H. Liu 
Name: Vivian H. Liu 
Title: Chief Executive Officer  

83

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
   
 
CERTIFICATION OF CHIEF FINANCIAL OFFICER  
PURSUANT TO  
18 U.S.C. SECTION 1350,  
AS ADOPTED PURSUANT TO  
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002  

Exhibit 32.2  

I, Mark Westgate, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the 
Sarbanes-Oxley Act of 2002, that, to my knowledge, the Annual Report of NexMed, Inc. on Form 10-K for 
the year ended December 31, 2008, fully complies with the requirements of Section 13(a) or 15(d) of the 
Securities Exchange Act of 1934 and that information contained in such Annual Report on 10-K fairly 
presents in all material respects the financial condition and results of operations of NexMed, Inc.  

Date: March 12, 2009.  

By: /s/ Mark Westgate  
Name: Mark Westgate 
Title: Chief Financial Officer 

84