Bausch Health
Annual Report 2010

Plain-text annual report

The future is clear Valeant Annual Report 2010 Company Overview Valeant Pharmaceuticals International, Inc. (NYSE/TSX:VRX) is a multi-national specialty pharmaceutical company that develops and markets prescription and nonprescription pharmaceutical products that make a meaningful difference in patients’ lives. Valeant is focused on the dermatology and neurology therapeutic areas primarily in the United States, Canada, Mexico, Brazil, Europe and Australia. In September 2010, Valeant Pharmaceuticals International and Biovail Corporation completed their previously announced merger to become one company. This compelling combination is expected to create tremendous value for stockholders of both companies as the businesses benefit from cost savings, greater scale, and enhanced financial strength and flexibility. Valeant’s strategy is to focus the business on core geographies and therapeutic classes, manage pipeline assets through strategic partnerships with other pharmaceutical companies and deploy cash with an appropriate mix of selective acquisitions, share buybacks and debt repurchases. Our leveraged research and development model is one key element to this business strategy and will allow us to progress development programs to drive future commercial growth, while minimizing our research and development expense. Based in Mississauga, Ontario, Canada, Valeant employs approximately 4,300 people worldwide. Revenue* U.S. Dermatology U.S. Neurology & Other Total U.S. Canada/Australia Specialty Pharmaceuticals Branded generics - Europe Branded generics - Latin America Branded Generics Total revenue Total product sales included above Twelve Months Ended December 31, 2010 $219,008 658,312 877,320 161,567 1,038,887 73,312 69,038 142,350 $1,181,237 $1,133,371 2009 $146,267 575,321 721,588 83,959 805,547 14,884 -- 14,884 $820,431 $789,026 * As a result of the Biovail’s merger with Valeant, revenue reflects Biovial standalone operations as they existed prior to the completion of the merger and combined Valeant’s results only for the period subsequent to the completion of the merger on September 28, 2010. Forward-Looking Statements In addition to current and historical information, this Annual Report contains forward-looking statements, including, without limitation, statements regarding our future operation and goals, our five-year strategic plan, anticipated cash flows, the growth and future development of the company and its business units, our ability to continue our performance and growth, our ability to increase sales growth or maintain market share of our products, product launches and extensions and expansion into different markets, our ability and success in integrating acquired businesses and/or products, our strategy regarding products and the development and approval of pipeline products. Words such as “expects,” “anticipates,” “intends,” “plans,” “should,” “could,” “would,” “may,” “will,” “believes,” “estimates,” “potential,” or “continue” or similar language identify forward-looking statements. Forward-looking statements involve known and unknown risks and uncertainties. Our actual results may differ materially from those contemplated by the forward-looking statements. Factors that might cause or contribute to these differences include, but are not limited to, risks and uncertainties discussed in our most recent annual or quarterly report filed with the U.S. Securities and Exchange Commission, which factors are incorporated herein by reference. You should consider these in evaluating our prospects and future financial performance. These forward-looking statements are made as of the date of this report. We disclaim any obligation to update or alter these forward-looking statements in this report or the other documents to reflect actual outcomes. Valeant Annual Report 2010 P1 By meeting our commitments our future is becoming clear. In 2010 we: > Created New Valeant through merger between Biovail and Valeant - Specialty pharmaceutical company focused on growth & cash flow generation - Diversified by product line, therapeutic area and geography - Scale, financial strength and complementary product lines accelerate growth opportunities - Focused growth platforms: Dermatology Emerging markets/branded generics > - Limited patent exposure Received unanimous positive vote for effectiveness of Potiga™ from FDA Advisory Panel - Received Complete Response letter in November with resubmission expected in early 2011 Valeant Annual Report 2010 P2 The Biovail/Valeant Merger On September 27, 2010, the stockholders of Valeant Pharmaceuticals International and Biovail Corporation overwhelming voted in favor of combining the two companies to become one under the Valeant name. Following the positive shareholder votes, former Valeant stockholders received a one-time special dividend of $16.77 per share and 1.7809 shares of Biovail common stock in exchange for each share of Valeant common stock they owned, while Biovail shareholders continued to own their existing common shares. The new combined company also completed a name change to Valeant Pharmaceuticals International, Inc. and our shares now trade on both the New York Stock Exchange and the Toronto Stock Exchange under the ticker symbol “VRX”. Total Revenue Results in Millions of Dollars $1,067,722 $842,818 $757,178 $820,430 $1,181,237 2006 2007 2008 2009 2010 * As a result of the Biovail’s merger with Valeant, revenue reflects Biovial standalone operations as they existed prior to the completion of the merger and combined Valeant’s results only for the period subsequent to the completion of the merger on September 28, 2010. Valeant Canada Specialty Pharmaceuticals Different Focus, Different Markets Our Specialty Pharmaceutical and Over-the-Counter (OTC) products are marketed under brand names and are sold in the United States, Canada and Australia, where we focus most of our efforts on the dermatology and neurology therapeutic classes. We also have branded generics and OTC operations in Europe and Latin America, which focuses on pharmaceutical products that are bioequivalent to original products and are marketed under company brand names. Valeant U.S. Specialty Pharmaceuticals & OTC Valeant Latin America Branded Generics & OTC Valeant Annual Report 2010 P3 Product sales as of 12/31/10 Estimated 2011 Geographic Breakdown Specialty Pharmaceuticals 69% Branded Generics 23% OTC 8% United States 58% Europe 18% Canada / Austrailia 12% Latin America 12% Valeant Europe Branded Generics Valeant Australia Specialty Pharmaceuticals & OTC Valeant Annual Report 2010 P4 Dear stockholders, We have now entered a truly exciting period in Valeant’s history that will build upon our significant achievements in 2010. First of all, I would like to highlight our single most significant transaction of 2010, the merger between Biovail Corporation and Valeant Pharmaceuticals International. The merger created Valeant Pharmaceuticals International, Inc. which is a nimble, lean, and geographically diversified company, as well as significantly stronger with a broader product portfolio and superior cash flow generation. This deal has advanced us on our journey to transform ourselves into a unique, growth based specialty pharmaceutical company. Moreover, the combined company – with steady and significant cash flows and minimal patent risk – will be able to create shareholder value at a level that would not have been possible for either company on a stand-alone basis. Legacy Biovail had a strategic plan based around a strong specialty central nervous system platform and other developing specialty areas, as well as the exploration of international opportunities. While Legacy Biovail made progress on these objectives over the last three years with several deals, the most notable of which included acquiring the U.S. rights to Wellbutrin XL, the worldwide rights to tetrabenazine, and the acquisition of Prestwick Pharmaceuticals, there was still much to be done. Valeant Annual Report 2010 P5 In the meantime, Legacy Valeant had been paving the way for growth through steadfast execution of its five-year strategic plan that balanced diverse specialties with a focused approach. Legacy Valeant consistently pursued unique opportunities to grow its business and to build a flexible and diversified pharmaceutical company that can respond to – and take advantage of – changes in the pharmaceutical industry. As a combined company, we will be able to leverage the combined company’s scale, financial strength and complementary product lines to pursue substantial growth opportunities and generate enhanced, long-term value for all of our shareholders. We will look to apply the Valeant operating philosophy to the combined portfolio, building on our track record to provide long-term value creation for our shareholders. As we take the next step in our transformation, we will just have to set the bar, and our stretch goals, even higher. Our future strategy and philosophy is both simple and powerful. It is anchored in diversified operating units led by empowered entrepreneurs – who will be rewarded for growing their businesses, and their cash flows, and building leadership positions in the marketplace. Our dual engines of growth will be superior execution of well thought through business plans and continued product renewal through acquisitions. We will do more with less than our competitors. Our vision for new Valeant is to become the leading specialty pharmaceutical company in the world. We will measure our success through our returns to our shareholders. We will have a balanced and diversified portfolio of businesses: in terms of types of products – branded pharmaceuticals, over the counter medications, branded generics, and unbranded generics; therapeutic areas - dermatology, neurology, and ophthalmology; and geographies - U.S., Canada, Central Europe, Latin America, and Australia. We will measure ourselves in terms of overall growth, organic growth, cash earnings, and adjusted cash flow from operations. Our portfolio will evolve over time. All of our assets are for sale if they are worth more to others than they are to our shareholders. However, if our operating units continue to meet their financial objectives, our bias will be to keep them. Over time, I would expect us to both enter and exit geographies, therapeutic areas, and potentially even product forms. We will continue to seek out high growth; high profit markets where we expect to have a competitive advantage, and exit markets where growth and profitability are no longer attractive. Again, we will measure our success through shareholder returns, not revenues, assets, or other measures. In terms of innovation, we will continue to invest in a leveraged R&D portfolio approach where we will seek partners for significant development efforts, thereby reducing our R&D expenditures as compared to our peers. While there are remarkable pharmaceutical companies involved in discovering new compounds, overall internal R&D for the pharmaceutical industry has not proven to be a good return for most companies over the last decade. And while we will continue some in-house development, our primary source of innovation will come through acquisitions of in-line products that we can grow through our infrastructure and commercial processes, as well as smart and focused life cycle management projects. Past examples of acquiring innovation include: CeraVe, Atralin, Wellbutrin XL, Lacrisert and Acanya, in the U.S., Dr. Renaud and Vital Science in Canada, DermaTech and Dr. Lewinns in Australia, EMO-FARM in Central Europe, Delta and Bunker in Brazil, and Tecnofarma in Mexico. We will operate a low cost operating model in all we do. In essence, we will continue to apply a low margin operating mindset to a high margin business. We will take pride in our frugality, our ability to make quick decisions based on internal resources, our willingness to all wear different hats at different times. Each of Valeant’s General Managers is expected to create a highly ethical environment for their employees. In the end, Valeant’s primary mission as an organization is to serve the patients and consumers who use our products, the physicians who prescribe and recommend those products, and the customers who provide retail outlets for these products. Valeant’s directive is to adhere to an extremely high ethical bar superseding any financial or other objective. 2010 The fourth quarter of 2010 was the first full quarter as the new Valeant. Our focus was on integrating the two companies and achieving our synergy targets. We now expect that the final tally of annual run rate synergies from the merger to be over $300 million in 2011. During 2010, Legacy Valeant also made eight additional acquisitions for a cost of approximately $450 million. These acquisitions strategically positioned us for enhanced sales growth in our selected markets and enabled us to expand our footprint and product offerings. Our expansion efforts in Canada and our first major steps in Brazil are examples of these efforts. These acquisitions had a combined $185 million in revenue, and we paid roughly 2.4 times sales for these acquisitions. I believe that like our past acquisitions, they will prove to be wise investments of our cash. Valeant Annual Report 2010 P6 Specialty Pharmaceutical and Over-the-Counter (OTC) We continue to operate our Specialty Pharmaceutical and Over-the-Counter (OTC) businesses in the U.S., Canada and Australia, although each market has its own set of opportunities and strategies. In these markets, we continue to solidify our position as a significant player in dermatology, an area that we consider a key strength for Valeant. 2010 was a solid year in which we made several dermatology acquisitions and solidified our position in dermatology. Legacy Valeant acquired Vital Science Corp., an OTC dermatology company located in Canada; as well as several privately–owned pharmacy skin care brands in Australia and the U.S. rights to commercialize Refissa®, a prescription- based topical tretinoin cream. The Specialty Pharmaceutical and OTC space is an exciting one which we hope to grow actively in 2011. The United States The U.S. dermatology business continues its strong growth trajectory. Our key acne brands, Acanya and Atralin, continue to show strong year-over-year growth. In the fourth quarter of 2010, retail drug store scans for CeraVe grew almost 100% versus 2009. A new distribution initiative for CeraVe in Wal-Mart, as well as three new product launches, has enabled this growth. This success has only been possible through the support of dermatologists and dermatology nurses. A recent online survey was performed asking 2,800 dermatology nurses which skincare moisturizing product they most recommended for their patients. Our product, CeraVe was ranked number one by over 70% of survey respondents, demonstrating the value of the brand to one of our most important stakeholders. In our U.S Neurology and Other segment, Wellbutrin remains an important product for Valeant. We are pleased to see our market share holding steady around 6% and we are implementing strategies to maintain this level in the future. As we have mentioned in the past, we continue to optimize several targeted non-field force strategies to support this brand. We are hopeful that we can continue to stabilize prescription volume. Canada We continue to see strong growth indicators in the Canadian market. The Biovail/Valeant merger has provided a solid platform to capitalize on these indicators. Legacy Biovail and Legacy Valeant had strong operations in Canada prior to the merger and it is a testament to our Canadian employees that they have managed to stay on track through the extensive integration activities over these past few months. In fact, our performance in 2010 when compared to 2009 shows the strengthening of the business over that of the historical growth rates of both businesses. In addition, we moved very quickly to integrate the commercial operations in Canada, finishing up our activities by the middle of December. Our key products in the Canadian market, Cesamet® Tiazac® XC and Wellbutrin® XL, experienced double digit prescription volume growth in 2010 and we have several new product launches planned for 2011, including Onsolis, Ziana and Opana. We have also been hard at work generating new deals to grow this business, completing three deals last year and two so far in 2011. Our successful track record in Canada, along with our strong commercial infrastructure, has made us logical partners for other companies looking for innovative ways to enter the Canadian market, without the risk and expense of building their own operational organization from scratch. Australia We continue to build our presence in the OTC market through the acquisitions of iconic brands in Australia. We do this with an ever increasing range of known and trusted brands in several categories including dermatology and cough and cold. Our known and trusted brands like Dermaveen®, Dermadrate®, Dermatix®and Pevaryl® are only sold through Pharmacy, while our legacy brand, Nyal® has been helping Australians to better health for almost 100 years. Others like UV Tripleguard® are well known and loved by Australians. In November 2010, we acquired well-established local brands such as Hamilton’s Suncare and Hamilton’s Skin Therapy, which are ranked #2 in suncare in the Australian pharmacy market. These leading skin care brands nicely augment Valeant’s current suncare product portfolio and expands our presence in the OTC market. The brands we acquired through our previous transactions have continued to perform well and have enhanced our portfolio and provided synergies to our growing pharmacy OTC platform. Our Branded Generics Emerging markets are an area of high focus for Valeant and we currently have operations in certain countries in Central Europe and Latin America. This business is focused on branded generic pharmaceuticals which are bioequivalent to original products but are marketed under the Company’s brand names. Branded generics are an attractive business for Valeant with low research and development costs and sustainable sales that do not face the patent expiry of traditional pharmaceutical compounds. Valeant Annual Report 2010 P7 Europe In 2010, Valeant’s European business primarily consists of operations in Poland, Hungary, Slovakia, Czech Republic, Bulgaria and Romania. Valeant is the 5th largest generic pharmaceutical company in Poland with an extensive sales and marketing infrastructure that has deep therapeutic and product expertise, as well as established relationships with key opinion leaders. With a state-of-the-art manufacturing plant in Poland providing a reliable source of supply and low production costs, Valeant’s management team members are proven performers with a history of acquiring and launching branded generic products. We recent announced an acquisition of PharmaSwiss S.A., a privately-owned branded generics and over-the- counter (OTC) pharmaceutical company based in Zug, Switzerland. PharmaSwiss has a broad product portfolio in seven therapeutic areas and operations in nineteen countries throughout Central and Eastern Europe, including Serbia, Poland, Hungary the Czech Republic. In addition, PharmaSwiss is an existing partner to several large pharmaceutical and biotech companies offering regional expertise in such functions as regulatory, compliance, sales, marketing and distribution. This acquisition is critical in our plans to become one of the leading branded generics companies in Central Europe. Not only do we build critical mass in this region with this acquisition, but we should realize significant synergies in our overlapping countries such as Poland, Hungary, Czech and Slovak. Now that the deal has closed, we have the opportunity to cross sell our current products into each other’s territories and to be an even more attractive partner to other pharmaceutical companies who would like a commercial partner for this region of the world. Latin America Valeant’s operations in Latin America consist of branded generics and OTC products in Mexico and Brazil. In Mexico, our branded generic and generic products are developed when patents or other regulatory exclusivity no longer protect an originator’s brand product and are primarily marketed to physicians and pharmacies through a broad sales force. We also have a generic portfolio that is primarily sold through the Mexican Government Health Care System, which awards its business through a tender process. Brazil is the ninth largest pharmaceutical market and the third largest dermatological market in the world. We were excited to advance our dermatology presence in the Brazilian market in 2010 through two acquisitions that brought us closer to building the critical mass we needed to accelerate success. We also acquired a state-of-the-art manufacturing plant that has the capacity to support our future growth strategies and will allow us to close our current subscale manufacturing facility, while reducing our dependency on third party manufacturers. We believe that our business in Brazil is now positioned for strong performance and growth. Potiga™/Trobalt™ We are excited about the progress we have been seeing on the development of our investigational anti-epileptic drug being studied for the adjunctive treatment of adults with partial-onset seizures. Known as Potiga™ in the U.S. and Trobalt™ outside the U.S., we believe Potiga™/Trobalt™ could offer an important adjunctive treatment option for partial-onset seizures that are not well-controlled. With an estimated 30% of people with epilepsy who do not have seizure control even with the best available medications, the treatment of epilepsy continues to be a large unmet medial need for these patients. On August 11, 2010, Valeant, along with our partner GlaxoSmithKline (GSK), announced that a U.S. Food and Drug Administration (FDA) advisory committee voted unanimously that clinical studies had provided substantial evidence of the effectiveness of Potiga™ as adjunctive treatment for adults with partial-onset seizures. The Peripheral and Central Nervous System Drugs Advisory Committee reviewed efficacy data from three pivotal studies of Potiga™ and an integrated safety data base including all patients who had at least one dose of Potiga™. Overall, Potiga™, as adjunctive therapy at a daily dose of 600, 900 or 1200 mg, reduced the median number of partial-onset seizures in adults with epilepsy not adequately controlled on one to three concomitant anti-epileptic drugs compared to placebo (standard therapy). The FDA panel reviewed the safety data, including urinary retention, infection and kidney stones, and the majority of Committee members voted that urinary retention could be mitigated by patient monitoring and discussed how this could be addressed. The Committee also voted unanimously that monitoring should not be instituted for infection and kidney stones. In November, we announced the receipt of a Complete Response letter from the FDA for the New Drug Application (NDA) for Potiga™. A Complete Response letter is issued by the FDA’s Center for Drug Evaluation and Research when the review of a file is completed and questions remain that preclude the approval of the NDA in its current form. GSK and Valeant evaluated the Complete Response letter in which FDA cited non-clinical reasons for this action and the two companies are working for a timely response to the FDA as soon as possible in 2011. Valeant Annual Report 2010 P8 In January 2011, we were notified that the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) had issued a positive opinion, recommending marketing authorization for Trobalt™ as an adjunctive (add-on) treatment of partial onset seizures and we received final marketing authorization in March 2011. In addition, Trobalt™ received a preliminary approval from the Swiss Agency for Therapeutic Products, Swissmedic, in December 2010. We are hopeful that our partner, GSK, will be in a position to launch Trobalt™ in Europe shortly. Looking Forward 2010 was another year of achievement and growth and as we continue to evolve into a stronger, more focused company, our efforts position us to reap numerous rewards now and in years to come. As we move forward, we will continue to pave the way for growth through the steadfast execution of our strategy that balances diverse specialties with a focused approach. We consistently look for unique opportunities in both therapeutic classes and geographic locations that other pharmaceutical companies might avoid, and I believe that the success we have achieved so far will generate more opportunities in the future. Our strong results demonstrate the strength of our base business and our ability to deliver growth, earnings and cash flows. Our ability to deliver solid growth is a testament to the value of our diversified business model, as well as our team’s ability to effectively manage our cost structure. We hope to continue to build on our past successes and look forward to new opportunities emerging for Valeant in 2011. Sincerely, J. Michael Pearson Chairman and Chief Executive Officer UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 (cid:2) (cid:3) FORM 10-K ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2010 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-14956 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. (Exact Name of Registrant as Specified in its Charter) CANADA State or other jurisdiction of incorporation or organization 98-0448205 (I.R.S. Employer Identification No.) 7150 Mississauga Road Mississauga, Ontario CANADA, L5N 8M5 (Address of principal executive offices) Registrant’s telephone number, including area code (905) 286-3000 Securities registered pursuant to Section 12(b) of the Act: Title of each class Name of each exchange on which registered Common Shares, No Par Value New York Stock Exchange, Toronto Stock Exchange Securities registered pursuant to section 12(g) of the Act: None (Title of class) Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes (cid:2) No (cid:3) Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes (cid:3) No (cid:2) Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or Section 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes (cid:2) No (cid:3) Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes (cid:2) No (cid:3) Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K. (cid:3) Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of ‘‘large accelerated filer,’’ ‘‘accelerated filer’’ and ‘‘smaller reporting company’’ in Rule 12b-2 of the Exchange Act. (Check one): Large accelerated filer (cid:2) Non-accelerated filer (cid:3) (Do not check if a smaller reporting company) Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes (cid:3) No (cid:2) Accelerated filer (cid:3) Smaller reporting company (cid:3) The aggregate market value of the common shares held by non-affiliates of the registrant as of the last business day of the registrant’s most recently completed second fiscal quarter was $3,051,152,000 based on the last reported sale price on the New York Stock Exchange on June 30, 2010. The number of outstanding shares of the registrant’s common stock, as of February 23, 2011 was 304,219,307. DOCUMENTS INCORPORATED BY REFERENCE Part III incorporates certain information by reference from the registrant’s proxy statement for the 2011 Annual Meeting of Shareholders. Such proxy statement will be filed no later than 120 days after the close of the registrant’s fiscal year ended December 31, 2010. TABLE OF CONTENTS GENERAL INFORMATION PART I Item 1. Item 1A. Item 1B. Item 2. Item 3. Item 4. Item 5. Item 6. Item 7. Item 7A. Item 8. Item 9. Item 9A. Item 9B. Item 10. Item 11. Item 12. Item 13. Item 14. Business . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Risk Factors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Unresolved Staff Comments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Properties . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Legal Proceedings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (Removed and Reserved) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PART II Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Selected Financial Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Management’s Discussion and Analysis of Financial Condition and Results of Operations Quantitative and Qualitative Disclosures About Market Risk . . . . . . . . . . . . . . . . . . . . . Financial Statements and Supplementary Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Changes in and Disagreements with Accountants on Accounting and Financial Disclosure Controls and Procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PART III Directors, Executive Officers and Corporate Governance . . . . . . . . . . . . . . . . . . . . . . . . Executive Compensation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Certain Relationships and Related Transactions, and Director Independence . . . . . . . . . . Principal Accounting Fees and Services . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Item 15. Exhibits and Financial Statement Schedules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SIGNATURES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PART IV Page 1 13 21 22 22 22 23 28 29 79 79 79 79 80 81 81 81 81 81 82 89 i Basis of Presentation General ‘‘Merger’’). In connection with the Merger, Biovail was renamed On September 28, 2010, Biovail Corporation (‘‘Biovail’’) completed the acquisition of Valeant Pharmaceuticals International (‘‘Valeant’’) through a wholly-owned subsidiary, pursuant to an Agreement and Plan of Merger, dated as of June 20, 2010, with Valeant surviving as a wholly-owned subsidiary of Biovail (the ‘‘Valeant Pharmaceuticals International, Inc.’’ Biovail is both the legal and accounting acquirer in the Merger. Accordingly, the pre-acquisition consolidated financial statements of Biovail will be treated as the historical financial statements of the Company going forward such that the accompanying financial statements reflect Biovail’s stand-alone operations as they existed prior to the completion of the Merger. The results of Valeant’s business have been included in the financial statements only for periods subsequent to the completion of the Merger. Except where the context otherwise requires, all references in this Annual Report on Form 10-K (‘‘Form 10-K’’) to the ‘‘Company’’, ‘‘we’’, ‘‘us’’, ‘‘our’’ or similar words or phrases are to Valeant Pharmaceuticals International, Inc. and its subsidiaries, taken together. In this Form 10-K, references to ‘‘$’’ and ‘‘US$’’ are to United States dollars and references to ‘‘C$’’ are to Canadian dollars. Unless otherwise indicated, the statistical and financial data contained in this Form 10-K are presented as of December 31, 2010. Trademarks The following words are trademarks of our Company and are the subject of either registration, or application for registration, in one or more of Canada, the United States of America (the ‘‘U.S.’’) or certain other jurisdictions: ACANYA(cid:4), ATTENADE(cid:5), A Tablet Design (Apex Down)(cid:4), A Tablet Design (Apex Up)(cid:4), APLENZIN(cid:4), ATIVAN(cid:4), ATRALIN(cid:4), ASOLZA(cid:5), BEDOYECTA(cid:4), BIOVAIL(cid:4), BIOVAIL CORPORATION INTERNATIONAL(cid:4), BIOVAIL & SWOOSH DESIGN(cid:4), BISOCARD(cid:4), BPI(cid:4), BVF(cid:4), CARDISENSE(cid:5), CARDIZEM(cid:4), CEFORM(cid:4), CERAVE(cid:4), CESAMET(cid:4), CHOLESTAGEL(cid:4), CRYSTAAL CORPORATION & DESIGN(cid:4), DEMSER(cid:4), DERMAVEEN(cid:4), DIASTAT(cid:4), DIASTAT(cid:4) ACUDIAL(cid:5), DITECH(cid:5), DR. LEWINN’S(cid:4), FLASHDOSE(cid:4), GLUMETZA(cid:4), INSTATAB(cid:5), ISORDIL(cid:4), JOVOLA(cid:5), JUBLIA(cid:5), KINERASE(cid:4), LABORATOIRE DR RENAUD(cid:4), LACRISERT(cid:4), MEPHYTON(cid:4), MESTINON(cid:4), MIGRANAL(cid:4), MIVURA(cid:5), M.V.I.(cid:4), NITOMAN(cid:4), NYAL(cid:4), ONELZA(cid:5), ONEXTEN(cid:5), ORAMELT(cid:5), PALVATA(cid:5), PERMAX(cid:4), RALIVIA(cid:4), SHEARFORM(cid:5), SMARTCOAT(cid:4), SOLBRI(cid:5), SYPRINE(cid:4), TESIVEE(cid:5), TIAZAC(cid:4), TITRADOSE(cid:4), TOVALT(cid:5), UPZIMIA(cid:5), VALEANT(cid:4), VALEANT V & DESIGN(cid:4), VALEANT PHARMACEUTICALS & DESIGN(cid:4), VASERETIC(cid:4), VASOTEC(cid:4), VEMRETA(cid:5), VITALSCIENCE(cid:4), VOLZELO(cid:5), XENAZINE(cid:4), XENAZINA(cid:4), and ZILERAN(cid:5). WELLBUTRIN(cid:4), WELLBUTRIN(cid:4) SR, WELLBUTRIN(cid:4) XL, WELLBUTRIN(cid:4) XR, ZOVIRAX(cid:4) and ZYBAN(cid:4) are trademarks of The GlaxoSmithKline Group of Companies and are used by us under license. ULTRAM(cid:4) is a trademark of Ortho-McNeil, Inc. (now known as PriCara, a division of Ortho-McNeil-Janssen Pharmaceuticals, Inc.) and is used by us under license. ACZONE(cid:5) is a trademark that is the subject of a trademark application by Allergan Sales, LLC and is used by us under license. MVE(cid:4) is a registered trademark of Healthpoint, Ltd. and is used by us under license. In addition, we have filed trademark applications for many of our other trademarks in Barbados, the U.S., Canada, and in other jurisdictions and have implemented, on an ongoing basis, a trademark protection program for new trademarks. Forward-Looking Statements Caution regarding forward-looking information and statements and ‘‘Safe Harbor’’ statements under the U.S. Private Securities Litigation Reform Act of 1995: To the extent any statements made in this Annual Report on Form 10-K contain information that is not historical, these statements are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and may be forward- looking information within the meaning defined under applicable Canadian securities legislation (collectively, ‘‘forward-looking statements’’). ii These forward-looking statements relate to, among other things: the expected benefits of the Merger, such as cost savings, operating synergies and growth potential of the Company; business plans and prospects, prospective products or product approvals, future performance or results of current and anticipated products; the impact of healthcare reform; exposure to foreign currency exchange rate changes and interest rate changes; the outcome of contingencies, such as certain litigation and regulatory proceedings; general market conditions; and our expectations regarding our financial performance, including revenues, expenses, gross margins, liquidity and income taxes. Forward-looking statements can generally be identified by the use of words such as ‘‘believe’’, ‘‘anticipate’’, ‘‘expect’’, ‘‘intend’’, ‘‘estimate’’, ‘‘plan’’, ‘‘continue’’, ‘‘will’’, ‘‘may’’, ‘‘could’’, ‘‘would’’, ‘‘target’’, ‘‘potential’’ and other similar expressions. In addition, any statements that refer to expectations, projections or other characterizations of future events or circumstances are forward-looking statements. These forward-looking statements may not be appropriate for other purposes. Although we have indicated above certain of these statements set out herein, all of the statements in this Form 10-K that contain forward-looking statements are qualified by these cautionary statements. Although we believe that the expectations reflected in such forward-looking statements are reasonable, such statements involve risks and uncertainties, and undue reliance should not be placed on such statements. Certain material factors or assumptions are applied in making forward-looking statements, including, but not limited to, factors and assumptions regarding the items outlined above. Actual results may differ materially from those expressed or implied in such statements. Important factors that could cause actual results to differ materially from these expectations include, among other things, the following: • our ability to compete against companies that are larger and have greater financial, technical and human resources than we do, as well as other competitive factors, such as technological advances achieved, patents obtained and new products introduced by our competitors; • factors relating to the integration of the businesses of Valeant and Biovail, including: our ability to integrate the business in the expected time frame, including the integration of the research and development, manufacturing, distribution, sales, marketing and promotion activities and financial and information technology systems of Valeant and Biovail; the difficulties of integrating personnel while maintaining focus on producing and delivering consistent, high quality products and retaining existing customers and attracting new customers; and the realization of the anticipated benefits, including cost savings, from such integration; • the challenges and difficulties associated with managing a larger, more complex, combined business; • our eligibility for benefits under tax treaties and the continued availability of low effective tax rates for the business profits of our significant operating subsidiary in Barbados; • our ability to retain, motivate and recruit executives and other key employees; • our future cash flow, our ability to service and repay our existing debt and our ability to raise additional funds, if needed, in light of our current and projected levels of operations, acquisition activity and general economic conditions; • our ability to identify, acquire and integrate acquisition targets and to secure and maintain third-party research, development, manufacturing, marketing or distribution arrangements; • the risks associated with the international scope of our operations; • the impacts of the Patient Protection and Affordable Care Act in the U.S. and other legislative and regulatory reforms in the countries in which we operate; • the uncertainties associated with the acquisition and launch of new products, including, but not limited to, the acceptance and demand for new pharmaceutical products, and the impact of competitive products and pricing; • the difficulty in predicting the expense, timing and outcome within our legal and regulatory environment, including, but not limited to, the U.S. Food and Drug Administration, the Canadian Therapeutic Products Directorate and European and Australian regulatory approvals, legal and regulatory proceedings and settlements thereof, the protection afforded by our patents and other intellectual and proprietary property, successful challenges to our generic products and infringement or alleged infringement of the intellectual property of others; iii • the success of preclinical and clinical trials for our drug development pipeline or delays in clinical trials that adversely impact the timely commercialization of our pipeline products; • the results of continuing safety and efficacy studies by industry and government agencies; • the risk that our products could cause, or be alleged to cause, personal injury, leading to withdrawals of products from the market; • our ability to obtain components, raw materials or other products supplied by third-parties; • the outcome of legal proceedings, investigations and regulatory proceedings; • economic factors over which the Company has no control, including changes in inflation, interest rates, foreign currency rates, and the potential effect of such factors on revenues, expenses and resulting margins; • the disruption of delivery of our products and the routine flow of manufactured goods across the U.S. border; and • other risks detailed from time to time in our filings with the Securities and Exchange Commission (the ‘‘SEC’’) and the Canadian Securities Administrators (the ‘‘CSA’’), as well as our ability to anticipate and manage the risks associated with the foregoing. Additional information about these factors and about the material factors or assumptions underlying such forward-looking statements may be found elsewhere in this Form 10-K, under Item 1A. ‘‘Risk Factors’’, and in the Company’s other filings with the SEC and CSA. We caution that the foregoing list of important factors that may affect future results is not exhaustive. When relying on our forward-looking statements to make decisions with respect to our Company, investors and others should carefully consider the foregoing factors and other uncertainties and potential events. These forward-looking statements speak only as of the date made. iv Item 1. Business PART I Biovail Corporation (‘‘Biovail’’) was formed under the Business Corporations Act (Ontario) on February 18, 2000, as a result of the amalgamation of TXM Corporation and Biovail Corporation International. Biovail was continued under the Canada Business Corporations Act (the ‘‘CBCA’’) effective June 29, 2005. On September 28, 2010 (the ‘‘Merger Date’’), Biovail completed the acquisition of Valeant Pharmaceuticals International (‘‘Valeant’’) through a wholly-owned subsidiary pursuant to an Agreement and Plan of Merger, dated as of June 20, 2010, with Valeant surviving as a wholly-owned subsidiary of Biovail (the ‘‘Merger’’). In connection with the Merger, Biovail was renamed ‘‘Valeant Pharmaceuticals International, Inc.’’ The accompanying financial statements reflect Biovail’s stand-alone operations as they existed prior to the completion of the Merger. The results of Valeant’s business have been included in the financial statements only for periods subsequent to the completion of the Merger. Unless the context indicates otherwise, when we refer to ‘‘we’’, ‘‘us’’, ‘‘our’’ or the ‘‘Company’’ in this Annual Report on Form 10-K (‘‘Form 10-K’’), we are referring to Valeant Pharmaceuticals International, Inc. and its subsidiaries on a consolidated basis. Introduction We are a multinational, specialty pharmaceutical company that develops, manufactures and markets a broad range of pharmaceutical products. Our specialty pharmaceutical and over-the-counter (‘‘OTC’’) products are marketed under brand names and are sold in the United States (‘‘U.S.’’), Canada, Australia and New Zealand, where we focus most of our efforts on products in the dermatology and neurology therapeutic classes. We also have branded generic and OTC operations in Europe and Latin America which focus on pharmaceutical products that are bioequivalent to original products and are marketed under company brand names. Business Strategy Since the Merger, our strategy has been to focus the business on core geographies and therapeutic classes, manage pipeline assets through strategic partnerships with other pharmaceutical companies and deploy cash with an appropriate mix of selective acquisitions, share buybacks and debt repurchases. We believe this strategy will allow us to improve both the growth rates and profitability of the Company and to enhance shareholder value, while exploiting the benefits of the Merger. Our leveraged research and development model is one key element to this business strategy. It will allow us to progress development programs to drive future commercial growth, while minimizing our research and development expense. This will be achieved in four ways: • structuring partnerships and collaborations so that our partners share development costs; • bringing products already developed for other markets to new territories; • acquiring dossiers and registrations for branded generic products, which require limited manufacturing start-up and development activities; and • selling internal development capabilities to third parties, thereby allowing higher utilization and infrastructure cost absorption. Focused Diversification across Geographies, Therapeutic Areas and Products with Limited Patent Exposure As a combined company, we are diverse not only in our sources of revenue from our broad drug portfolio, but also among the therapeutic classes and geographic segments we serve. We have a focused geographic footprint and focus on those businesses that we view to have the potential for strong operating margins and solid growth, while providing natural balance across geographies. 1 In addition, we have an established portfolio of specialty pharmaceutical, branded generic and OTC products with a focus in the dermatology therapeutic areas. We believe dermatology is particularly attractive given that many of the products are: • generally relatively small on an individual basis (with the exception of Zovirax(cid:4)), and therefore not the focus of larger pharmaceutical companies; • marked by a significant self-pay component, so that they are not as dependent on increasing reimbursement pressures; and • often topical treatments and, therefore, subject to less generic competition. In the U.S. market, topical treatments require full clinical trials and not just bioequivalence tests before generics can enter the market. Acquisitions Cholestagel(cid:4) On February 9, 2011, we acquired the Canadian rights to Cholestagel(cid:4), an oral bile acid sequestrant for hypercholesterolemia, from Genzyme Corporation for a $2.0 million upfront payment, to be followed by potential additional milestone payments totaling up to $7.0 million. ACZONE(cid:4) On February 7, 2011, we entered into an agreement to license the Canadian rights to ACZONE(cid:4) Gel 5%, a topical formulation of dapsone used in the treatment of acne vulgaris, from Allergan, Inc. for an upfront payment of approximately $0.5 million and subsequent additional payments based on net sales. Zovirax(cid:4) On February 2, 2011, we entered into an asset purchase agreement to acquire U.S. rights to non-ophthalmic topical formulations of Zovirax(cid:4) from GlaxoSmithKline LLC (the entities within The Glaxo Group of Companies are referred to throughout as ‘‘GSK’’). Following receipt of Hart-Scott-Rodino regulatory clearance, we closed the U.S. transaction on February 22, 2011. In addition, concurrent with the execution of the U.S. agreement, we entered into a binding letter of intent with GSK to acquire the Canadian rights to non-ophthalmic topical formulations of Zovirax(cid:4) and we are in the process of negotiating a definitive agreement for such acquisition. Pursuant to the terms of the asset purchase agreement, we paid to GSK an aggregate amount of $300.0 million in cash for both the U.S. and Canadian rights upon the closing of the U.S. transaction. No additional payments will be made to GSK upon the closing of the Canadian transaction. We have been marketing Zovirax(cid:4) in the U.S. since January 1, 2002, under a 20-year exclusive distribution agreement with GSK, which distribution agreement terminated following the closing of the U.S. transaction. Upon the closing of the U.S. transaction, we entered into a new supply agreement and a new trademark and domain name license agreement with GSK with respect to the U.S. territory. Pursuant to the terms of the trademark and domain name license agreement, we have been granted an exclusive royalty-free license, terminable only for breach or by mutual agreement of the parties, to use the Zovirax(cid:4) mark and trade dress and the zovirax.com domain name in connection with the advertising, promotion, manufacture, sale and distribution, in the U.S., of topical non-ophthalmic products containing acyclovir (including Zovirax(cid:4) Ointment and Zovirax(cid:4) Cream). The asset purchase agreement with GSK is attached as Exhibit 2.8 to this Form 10-K and the trademark and domain name license agreement with GSK is attached as Exhibit 10.31 to this Form 10-K. PharmaSwiss On January 31, 2011, we entered into a stock purchase agreement to purchase all of the issued and outstanding stock of PharmaSwiss S.A. (‘‘PharmaSwiss’’), a privately-owned branded generics and OTC pharmaceutical company based in Zug, Switzerland. The aggregate consideration payable is A350.0 million (approximately $479.0 million as of January 31, 2011) plus up to an additional A30.0 million (approximately 2 $41.0 million as of January 31, 2011) in contingent payments if certain net sales milestones of PharmaSwiss are achieved for the calendar year ended 2011. PharmaSwiss is an existing partner to several large pharmaceutical and biotech companies offering regional expertise in such functions as regulatory, compliance, sales, marketing and distribution, in addition to developing its own product portfolio. Through its business operations, PharmaSwiss offers a broad product portfolio in seven therapeutic areas and operations in 19 countries throughout Central and Eastern Europe, including Poland, Hungary, the Czech Republic and Serbia, as well as in Greece and Israel. The transaction, which is subject to customary closing conditions, including certain regulatory approvals, is expected to close in the first quarter of 2011. Ribavirin/Taribavirin Agreements On November 1, 2010, we entered into two strategic agreements for the development and commercialization of taribavirin and the commercial marketing of ribavirin in the treatment of viral diseases, including hepatitis C virus (HCV). Under the terms of the first agreement, Valeant paid Kadmon Pharmaceuticals LLC (‘‘Kadmon’’) $7.5 million for exclusive rights to all Kadmon dosage forms of ribavirin, including 200 mg, 400 mg, and 600 mg tablets and capsules, in Poland, Hungary, the Czech Republic, Slovakia, Romania and Bulgaria. Valeant will source these products from Kadmon. Under the terms of a second agreement, Valeant granted Kadmon an exclusive, worldwide license to taribavirin, excluding the territory of Japan, in exchange for an upfront payment of $5.0 million, other development milestones, and royalty payments in the range of 8-12% of future net sales. The fair value associated with taribavirin was included in the acquired in-process research and development (‘‘IPR&D’’) assets identified as of the Merger Date. Hamilton Brands On October 29, 2010, we acquired several privately-owned pharmacy skin care brands in Australia. The leading brands, including well-established local brands such as Hamilton’s Suncare and Hamilton’s Skin Therapy, are ranked number 2 in suncare in the Australian pharmacy market. Total annualized sales of the acquired products are approximately $10.0 million. Istradefylline On June 2, 2010, we entered into a license agreement with Kyowa Hakko Kirin Co., Ltd. (‘‘Kyowa Hakko Kirin’’) to acquire the U.S. and Canadian rights to develop and commercialize products containing istradefylline — a new chemical entity targeted for the treatment of Parkinson’s disease. Under the terms of the license agreement, we paid an upfront fee of $10.0 million, and we could pay up to $20.0 million in potential development milestones through U.S. Food and Drug Administration (‘‘FDA’’) approval and up to an additional $35.0 million if certain sales-based milestones are met. We will also make tiered royalty payments of up to 30% on net commercial sales of products containing istradefylline. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, the $10.0 million upfront payment, together with $0.2 million of acquisition costs, was charged to acquired IPR&D expense in the second quarter of 2010. In connection with this acquisition, we also entered into an agreement with Kyowa Hakko Kirin for the supply of the istradefylline compound. AMPAKINE(cid:4) On March 25, 2010, we acquired certain AMPAKINE(cid:4) compounds, including associated intellectual property, from Cortex Pharmaceuticals, Inc. (‘‘Cortex’’) for use in the field of respiratory depression, a brain- mediated breathing disorder. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, the $9.0 million upfront payment and the $1.0 million transition payment made by us to Cortex, together with $0.7 million of acquisition costs, were charged to acquired IPR&D expense in the first quarter of 2010. As described below under ‘‘Products in Development’’, we have suspended development of the AMPAKINE(cid:4) compounds and are reviewing our options with Cortex. 3 Staccato(cid:4) Loxapine into a collaboration and On February 9, 2010, we entered license agreement with Alexza Pharmaceuticals, Inc. (‘‘Alexza’’) to acquire the U.S. and Canadian development and commercialization rights to AZ-004 for the treatment of psychiatric and/or neurological indications and the symptoms associated with these indications. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, the $40.0 million upfront payment made by us to Alexza, together with $0.3 million of acquisition costs, was charged to acquired IPR&D expense in the first quarter of 2010. As described below under ‘‘Products in Development’’, by notice to Alexza dated October 18, 2010, we terminated our agreement with Alexza, effective January 16, 2011. For more information regarding these acquisitions, see Note 4 of notes to consolidated financial statements in Item 15 of this Form 10-K. Segment Information Since the Merger, we have operated in five business segments comprising (i) U.S. Neurology and Other, (ii) U.S Dermatology, (iii) Canada and Australia, (iv) Branded Generics — Europe, and (v) Branded Generics — Latin America. Within our U.S. Dermatology and U.S. Neurology and Other segments, we generate alliance revenue from the licensing of products we developed or acquired. Additionally, within our U.S. Dermatology segment we generate service revenue from contract services in the areas of dermatology and topical medication. We have realigned segment financial data for the years ended December 31, 2009 and 2008 to reflect changes in our organizational structure that occurred in 2010. Comparative segment information for 2010, 2009 and 2008 is presented in Note 26 of notes to consolidated financial statements in Item 15 of this Form 10-K. Our current product portfolio comprises approximately 490 products, with approximately 2,500 stock keeping units (‘‘SKUs’’). In 2010, 2009 and 2008, Wellbutrin XL(cid:4) represented 21%, 22% and 17%, respectively, and Zovirax(cid:4) represented 14%, 19% and 21%, respectively, of our consolidated revenues. We anticipate that the percentage of consolidated revenue represented by these two products will decline in 2011 with the inclusion of a full year of revenue from both the Valeant and Biovail products. U.S. Neurology and Other The U.S. Neurology and Other segment generates product revenues from pharmaceutical and OTC products. These pharmaceutical products are marketed and sold primarily through wholesalers. Neurology and Other Products — our principal Neurology and Other products are: • Wellbutrin XL(cid:4), an extended-release formulation of bupropion indicated for the treatment of major depressive disorder in adults, was launched in the U.S. in September 2003 by an affiliate of GSK. Pursuant to a manufacturing-and-supply agreement then in effect with GSK, Biovail received a tiered supply price based on GSK’s net sales of Wellbutrin XL(cid:4). In May 2009, Biovail acquired the full U.S. commercialization rights to Wellbutrin XL(cid:4) from GSK. • Xenazine(cid:4) is indicated for the treatment of chorea associated with Huntington’s disease. In the U.S., Xenazine(cid:4) is distributed for us by Lundbeck Inc. under an exclusive marketing, distribution and supply agreement for an initial term of 15 years. U.S. Neurology and Other Alliance Revenue — We generate alliance revenue from the licensing of various products we have developed or acquired. U.S. Dermatology The U.S. Dermatology segment generates product revenues from pharmaceutical and OTC products. These pharmaceutical products are marketed and sold primarily through wholesalers and to a lesser extent through retail and direct-to-physician channels. 4 Dermatology Products — Our principal dermatology products are: • Zovirax(cid:4) Ointment is a topical formulation of a synthetic nucleoside analogue which is active against herpes viruses. Each gram of Zovirax(cid:4) Ointment contains 50 mg of acyclovir in a polyethylene glycol base. This product is indicated for the management of initial genital herpes and in limited non-life threatening mucocutaneous herpes simplex infections in immuno-compromised patients. Zovirax(cid:4) Cream was approved by the FDA in December 2002 and launched by Biovail in July 2003. Zovirax(cid:4) Cream is indicated for the treatment of recurrent herpes labialis (cold sores) in adults and adolescents (12 years of age and older). Pursuant to a distribution rights agreement, GSK provided us with Zovirax(cid:4) products for the U.S. This distribution rights agreement terminated in February 2011 with our acquisition of the U.S. rights to non-ophthalmic topical formulations of Zovirax(cid:4) from GSK. We have entered into a new supply agreement and trademark license with GSK for the U.S. • Acanya(cid:4) gel is a fixed-combination clindamycin (1.2%)/benzoyl peroxide (2.5%) aqueous gel approved by the FDA for the treatment of acne vulgaris in patients 12 years and older. Studied in patients with moderate and severe acne, Acanya(cid:4) is a once-daily formulation that offers high efficacy with a favorable tolerability profile. Acanya(cid:4) was launched by Valeant in March 2009. • Atralin(cid:4) gel is an aqueous gel containing tretinoin (0.05%) approved for acne vulgaris in patients 10 years and older. Atralin(cid:4) has been demonstrated to reduce acne lesions as early as one month after the start of treatment and contains ingredients (hyaluronic acid, collagen and glycerin) known to moisturize and hydrate the skin. OTC Products — our principal OTC products are: • CeraVe(cid:4) is a range of over-the-counter products with essential ceramides and other skin-nourishing and skin-moisturizing ingredients (humectants and emollients) combined with a unique, patented Multivesicular Emulsion (MVE(cid:4)) delivery technology that, together, work to rebuild and repair the skin barrier. CeraVe(cid:4) formulations incorporate ceramides, cholesterol and fatty acids, all of which are essential for skin barrier repair and are used as adjunct therapy in the management of various skin conditions. • Kinerase(cid:4) is a range of over-the-counter and prescription cosmetic products that have been shown to help skin look smoother, younger and healthier. Kinerase(cid:4) contains the synthetic plant growth factor N6-furfuryladenine which has been shown to slow the changes that naturally occur in the cell aging process in plants and in skin cells. U.S. Dermatology Service and Alliance Revenue — We generate alliance revenue and service revenue from the licensing of dermatological products and from contract services in the areas of dermatology and topical medication. Alliance revenue within our U.S Dermatology segment currently includes profit sharing payments from the sale of a 1% clindamycin and 5% benzoyl peroxide gel product (‘‘IDP-111’’) by Mylan Pharmaceuticals, Inc., and royalties from patent-protected formulations developed by our Dow Pharmaceutical Sciences, Inc. subsidiary and licensed to third parties. Contract services are primarily focused on contract research for external development and clinical research in areas such as formulations development, in vitro drug penetration studies, analytical sciences and consulting in the areas of labeling and regulatory affairs. Canada and Australia The Canada and Australia segment generates product revenues from pharmaceutical and OTC products. These pharmaceutical products are marketed and sold primarily through wholesalers and to a lesser extent through retail and direct-to-physician channels. Canada — our principal products sold in the Canadian market are: • Tiazac(cid:4) XC is a calcium channel blocker (‘‘CCB’’) used in the treatment of hypertension and angina. Tiazac(cid:4) XC is a once-daily formulation of diltiazem that delivers smooth blood pressure control over a 24-hour period. As a non-dihydropyridine CCB, Tiazac(cid:4) XC provides specific renal protective benefits as well as blood pressure reduction, which is particularly important for diabetic hypertensive patients. Our generic version of Tiazac(cid:4) XC is distributed in Canada by Teva Canada. 5 • Wellbutrin(cid:4) XL is a once-daily formulation of bupropion developed by Biovail that is approved for the treatment of major depressive illness and the prevention of seasonal major depressive illness. • Cesamet(cid:4) is a synthetic cannabinoid sold in Canada. It is indicated for the management of severe nausea and vomiting associated with cancer chemotherapy. • We sell topical OTC products under the trade names Laboratoire Dr Renaud(cid:4) and VitalScience(cid:4) in Canada. Valeant acquired Laboratoire Dr Renaud(cid:4) and VitalScience(cid:4) in 2009 and 2010, respectively. Australia — From and after the Merger, we have sold topical OTC products under the tradenames Dermaveen(cid:4), Dr. LeWinn’s(cid:4) and Hamilton’s in Australia, as well as Nyal(cid:4), an Australian range of over-the-counter products covering an extensive range of tablets, liquids and nasal sprays to treat cough, cold, flu, sinus and hayfever symptoms. Branded Generics — Europe The Branded Generics — Europe segment generates revenues from branded generic pharmaceutical products primarily in Poland, Hungary, the Czech Republic and Slovakia. Our Branded Generics — Europe segment develops, manufactures and markets products that are the therapeutic equivalent to their brand name counterparts, which are developed when patents or other regulatory exclusivity no longer protect an originator’s brand product. Our branded generics strategy is to develop a commercialization strategy to differentiate these products through innovative marketing tactics. Our products in this region are sold under the ICN Polfa brand name and we market our portfolio of generic branded products to doctors and pharmacists through approximately 300 sales professionals. Our branded generics cover a broad range of treatments including antibiotics, treatments for cardivascular diseases, antifungal medications and diabetic therapies among many others. Our largest product in this market is Bisocard(cid:4), a Beta-blocker that is indicated to treat hypertension and angina pectoris. Syncumar is a courmarin that is used as an anti-coagulant for the treatment and prevention of thromboembolic diseases. Sinupret is an herbal supplement that is claimed to be beneficial for supporting healthy sinus and respiratory function. It is commonly used for the treatment of allergies, coughs, colds and sinus infections. Tetrabenazine has also been approved for use in a number of countries in Europe and we have distribution arrangements for tetrabenazine in Denmark, Finland, France, Germany, Ireland, Israel, Italy, the Netherlands, Portugal, Spain, Switzerland and the United Kingdom. On January 31, 2011, we entered into a stock purchase agreement to purchase all of the issued and outstanding stock of PharmaSwiss, a privately-owned branded generics and OTC pharmaceutical company with a broad product portfolio in seven therapeutic areas and operations in 19 countries throughout Central and Eastern Europe, including Poland, Hungary, the Czech Republic and Serbia, as well as in Greece and Israel. Branded Generics — Latin America The Branded Generics — Latin America segment generates revenues from branded generic pharmaceutical products and OTC products in Mexico and Brazil and exports out of Mexico to other Latin American markets. The Mexico domestic market represents approximately 62% of revenues in this segment for the year ended December 31, 2010. Our branded generic and generic products are developed when patents or other regulatory exclusivity no longer protect an originator’s brand product. Our branded generic products are primarily marketed to physicians and pharmacies through approximately 500 sales professionals under the Grossman and Tecnofarma brands. Our Tecnofarma generic portfolio is primarily sold through Mexico’s Government Health Care System, which awards its business through a tender process. Our portfolio covers a broad range of therapeutic classes including vitamin deficiency, antibacterials and dermatology. Our largest product in this market is Bedoyecta(cid:4), a brand of vitamin B complex (B1, B6 and B12 vitamins) products. Bedoyecta(cid:4) products act as energy improvement agents for fatigue related to age or chronic diseases, and as nervous system maintenance agents to treat neurotic pain and neuropathy. Bedoyecta(cid:4) is sold in an injectable form as well as in a tablet form in Mexico and has strong brand recognition in Mexico. 6 Our second largest product, M.V.I.(cid:4), multi-vitamin infusion, is a hospital dietary supplement used in treating trauma and burns. For detailed information regarding the revenues, operating profits and identifiable assets attributable to our operating segments, see Note 26 of notes to consolidated financial statements in Item 15 of this Form 10-K. Collaboration Agreement In October 2008, Valeant closed the worldwide License and Collaboration Agreement (the ‘‘Collaboration Agreement’’) with GSK to develop and commercialize ezogabine/retigabine, a first-in-class neuronal potassium channel opener for the treatment of adult epilepsy patients with refractory partial onset seizures, and its backup compounds. We agreed to share equally with GSK the development and pre-commercialization expenses of ezogabine/retigabine in the U.S., Australia, New Zealand, Canada and Puerto Rico (the ‘‘Collaboration Territory’’) and GSK will develop and commercialize ezogabine/retigabine in the rest of the world. Our share of such expenses in the Collaboration Territory is limited to $100.0 million, provided that GSK will be entitled to credit our share of any such expenses in excess of such amount against future payments owed to us under the Collaboration Agreement. See Note 5 of notes to consolidated financial statements in Item 15 of this Form 10-K for further information. GSK has the right to terminate the Collaboration Agreement at any time prior to the receipt of the approval by the FDA of an NDA for an ezogabine/retigabine product, which right may be irrevocably waived at any time by GSK. Our rights to ezogabine/retigabine are subject to an Asset Purchase Agreement between Meda Pharma GmbH & Co. KG (‘‘Meda Pharma’’) and Xcel Pharmaceuticals, Inc. (‘‘Xcel’’), which was acquired by Valeant in 2005 (the ‘‘Meda Pharma Agreement’’). Under the Meda Pharma agreement, we are required to make certain milestone and royalty payments to Meda Pharma. Within the Collaboration Territory, any royalties payable to Meda Pharma will be paid by us and GSK. In the rest of the world, we will be responsible for the payment of these royalties to Meda Pharma out of the royalty payments we receive from GSK. Research and Development Our research and development organization focuses on the development of products through clinical trials. We currently have a number of compounds in clinical development: ezogabine/retigabine, IDP-107, IDP-108, IDP-109, IDP-115, IDP-118, istradefylline and several lifecycle management projects. Our research and development expenses for the years ended December 31, 2010, 2009 and 2008 were $68.3 million, $47.6 million and $69.8 million, respectively. As of December 31, 2010, approximately 300 employees were involved in our research and development efforts. Products in Development Prior to the Merger, Biovail’s product development and business development efforts were focused on unmet medical needs in specialty central nervous system (‘‘CNS’’) disorders. Since the Merger, the Company has been employing a leveraged research and development model that will allow it to progress development programs, while minimizing research and development expense, through partnerships and other means. In consideration of this model, following the Merger, the Company conducted a strategic and financial review of the Biovail product development pipeline and identified the programs that did not align with the Company’s new research and development model, as outlined in the table below. In respect of the Staccato(cid:4) loxapine, GDNF, fipamezole and pimavanserin programs, the Company provided notices of termination to, or entered into 7 termination agreements with, the counterparties to the agreements. Regarding the AMPAKINE(cid:4) program, the Company has suspended development of these compounds and is reviewing its options with Cortex. Program Counterparty Compound AZ-004 BVF-007 BVF-014 BVF-018 BVF-025 BVF-036, (cid:6)040, (cid:6)048 Alexza Pharmaceuticals, Inc. Cortex Pharmaceuticals, Inc. MedGenesis Therapeutix Inc. LifeHealth Limited Santhera Pharmaceuticals (Switzerland) Ltd. ACADIA Pharmaceuticals Inc. Staccato(cid:4) loxapine AMPAKINE(cid:4) GDNF Tetrabenazine Fipamezole Pimavanserin Contingent Milestone Obligations Terminated(1) ($ in 000s) $ 90,000 $ 15,000 $ 20,000 Nil $200,000 $365,000 Termination Charges Nil Nil $ 5,000(2) $28,000(3) Nil $ 8,750(2) (1) Represents the maximum amount of previously disclosed milestone payments we could have been required to make to the counterparty under each agreement. These milestone payments were contingent on the achievement of specific developmental, regulatory and commercial milestones. In addition, we could have been obligated to make royalty payments based on future net sales of the products if regulatory approval was obtained. As a consequence of the termination of these arrangements, we have no ongoing or future obligation in respect of these milestone or royalty payments. (2) Represents the amount of negotiated settlements with each counterparty that we recognized and paid in the fourth quarter of 2010. (3) Represents the carrying amount of related IPR&D asset capitalized in connection with the acquisition of the worldwide development and commercialization rights to tetrabenazine in June 2009. We currently have the following products, among others, in clinical development: • Ezogabine/retigabine In collaboration with GSK, we are developing a compound as an adjunctive treatment for partial-onset seizures in patients with epilepsy whose generic name will be ezogabine in the U.S. and retigabine in all other countries. Ezogabine/retigabine stabilizes hyper-excited neurons primarily by opening neuronal potassium channels. On October 30, 2009, an NDA was filed for ezogabine for the treatment of refractory partial-onset seizures and the FDA accepted the NDA for review on December 29, 2009. On August 30, 2010, the FDA extended the Prescription Drug User Fee Act (‘‘PDUFA’’) goal date for ezogabine to November 30, 2010 due to the recent submission of a solicited formal Risk Evaluation and Mitigation Strategy (‘‘REMS’’). The REMS was requested by the FDA in correspondence dated August 16, 2010, and was submitted to the FDA on August 26, 2010. On November 30, 2010, we received a Complete Response Letter from the FDA for ezogabine. We are evaluating the Complete Response Letter in which the FDA cited non-clinical reasons for this action and believe that these items can be addressed and are working for a timely response to the FDA as soon as possible in 2011. Also, the European Medicines Evaluation Agency (‘‘EMEA’’) confirmed on November 17, 2009 that the Marketing Authorization Application (‘‘MAA’’) filed on October 30, 2009 for ezogabine/retigabine was successfully validated, thus enabling the MAA review to commence. In January 2011, the European Medicines Agency’s Committee for Medicinal Products for Human Use (‘‘CHMP’’) issued an opinion recommending marketing authorization for Trobalt(cid:5) (retigabine) as an adjunctive (add-on) treatment of partial-onset seizures, with or without secondary generalization in adults aged 18 years and above with epilepsy. Additionally, retigabine received a preliminary approval from the Swiss Agency for Therapeutic Products, Swissmedic, in December 2010. • Dermatology Products A number of dermatology product candidates are in development including: • IDP-107 is an oral treatment for moderate to severe acne vulgaris. Acne is a disorder of the pilosebaceous unit characterized by the presence of inflammatory (pimples) and non-inflammatory (whiteheads and blackheads) lesions, predominately on the face. Acne vulgaris is a common skin disorder that affects about 85% of people at some point in their lives. We are currently enrolling patients in a Phase 2b clinical trial to evaluate the safety and efficacy of IDP-107. 8 • IDP-108, a novel triazole compound, is an antifungal targeted to treat onychomycosis, a fungal infection of the fingernails and toenails primarily in older adults. The mechanism of antifungal activity appears similar to other antifungal triazoles, i.e., ergosterol synthesis inhibition. IDP-108 is a non-lacquer formulation designed for topical delivery into the nail. We are currently conducting a Phase 3 clinical trial to evaluate the safety and efficacy of IDP-108. • IDP-109 is a compound targeted for treatment of common warts. There is no currently approved prescription treatment for common warts. Common warts is an infection caused by a viral infection (human papilloma virus) and occurs most frequently on the hands. This product is currently in Phase 1 stage of development. • IDP-115 combines an established anti-rosacea active ingredient with sunscreen agents to provide sun protection in the same topical treatment for rosacea patients. Rosacea is a common condition treated by dermatologists and characterized by multiple signs and symptoms including papules, pustules and erythema, most commonly on the central area of the face. This product has completed Phase 2 clinical trials. • IDP-118 is a topical product targeted to treat psoriasis. Psoriasis is a chronic, autoimmune disease that appears on the skin. This product is currently in Phase 1 stage of development. • Istradefylline On June 2, 2010, Biovail entered into a license agreement with Kyowa Hakko Kirin to acquire the U.S. and Canadian rights to develop and commercialize products containing istradefylline. In April 2007, Kyowa Hakko Kirin filed an NDA for istradefylline, which received a Not Approvable letter from the FDA in February 2008. The FDA has requested a Complete Response to the Not Approvable letter before it will consider meeting with us to discuss the regulatory approval process for istradefylline. • Lifecycle Management Projects Through Valeant’s acquisition of Aton Pharma, Inc. in May 2010, we have ongoing lifecycle management programs in place for several of our specialty CNS compounds, including Syprine(cid:4) and Mephyton(cid:4), as well as Lacrisert(cid:4), which is in our dermatology portfolio. We are developing improvements to these compounds in order to better meet the needs expressed by the medical community. Licenses and Patents (Proprietary Rights) Data and Patent Exclusivity We rely on a combination of regulatory and patent rights to protect the value of our investment in the development of our products. A patent is the grant of a property right which allows its holder to exclude others from, among other things, selling the subject invention in, or importing such invention into, the jurisdiction that granted the patent. In the U.S., Canada and the European Union, patents expire 20 years from the date of application. In the U.S., the Hatch-Waxman Act provides nonpatent regulatory exclusivity for five years from the date of the first FDA approval of a new drug compound in an NDA. The FDA is prohibited during those five years from approving a generic, or ANDA, that references the NDA. Protection under the Hatch-Waxman Act will not prevent the filing or approval of another full NDA. However, the NDA applicant would be required to conduct its own pre-clinical, adequate and well-controlled clinical trials to independently demonstrate safety and effectiveness. A similar data exclusivity scheme exists in the European Union, whereby only the pioneer drug company can use data obtained at the pioneer’s expense for up to eight years from the date of the first approval of a drug by the EMEA and no generic drug can be marketed for ten years from the approval of the innovator product. Under both the U.S. and the European Union data exclusivity programs, products without patent protection can be marketed by others so long as they repeat the clinical trials necessary to show safety and efficacy. Canada employs a similar regulatory regime. 9 Exclusivity Rights with Respect to ezogabine/retigabine We own a U.S. composition of matter patent (which will expire in 2013) directed to ezogabine/retigabine without regard to crystalline form. We anticipate that this patent will be extended to 2018 upon approval of ezogabine/retigabine pursuant to the patent term restoration provisions of the Hatch-Waxman Act. We also own two U.S. patents (both of which will expire in 2018) that are directed to specific crystalline forms of ezogabine/retigabine. In addition, we own a number of U.S. patents and pending applications, with expiration dates ranging from 2016 to 2023, directed to the use of ezogabine/retigabine to treat a variety of disease indications. We also own several patents and pending applications in foreign countries with expiration dates ranging from 2012 to 2024. Upon regulatory approval, we expect to obtain five years of data exclusivity in the U.S. and ten years in Europe for ezogabine/retigabine. Government Regulations Government authorities in the U.S., at the federal, state and local level, in Canada and in other countries extensively regulate, among other things, the research, development, testing, approval, manufacturing, labeling, post-approval monitoring and reporting, packaging, promotion, storage, advertising, distribution, marketing and export and import of pharmaceutical products. The process of obtaining regulatory approvals and the subsequent compliance with appropriate federal, state, local and foreign statutes and regulations require the expenditure of substantial time and financial resources. FDA approval must be obtained in the U.S., approval of Health Canada’s Therapeutic Products Directorate (‘‘TPD’’) must be obtained in Canada, EMEA approval must be obtained for countries that are part of the European Union and approval must be obtained from comparable agencies in other countries prior to marketing or manufacturing new pharmaceutical products for use by humans. Manufacturers of drug products are required to comply with manufacturing regulations, including current good manufacturing regulations enforced by the FDA and the TPD and similar regulations enforced by regulatory agencies outside the U.S. and Canada. In addition, we are subject to price control restrictions on our pharmaceutical products in many countries in which we operate. We are also subject to extensive health care marketing and fraud and abuse regulation in the U.S. by the federal and state governments, such as the federal False Claims Act, and similar regulations in Canada and foreign countries in which we may conduct our business. The federal False Claims Act imposes civil and criminal liability on individuals or entities who submit (or cause the submission of) false or fraudulent claims for payment to the government. If our operations are found to be in violation of any of these laws, regulations, rules or policies or any other law or governmental regulation, or if interpretations of the foregoing change, we may be subject to civil and criminal penalties, damages, fines, exclusion from the Medicare and Medicaid programs and the curtailment or restructuring of our operations. Environmental Regulation We are subject to national, state and local environmental laws and regulations, including those governing the handling and disposal of hazardous wastes, wastewater, solid waste and other environmental matters. Our development and manufacturing activities involve the controlled use of hazardous materials. Marketing and Customers Prior to the Merger, our primary markets were the U.S. and Canada. Subsequent to the Merger, our four major geographic markets are: the U.S., Canada, Mexico and Poland. 10 The following table identifies external customers that accounted for 10% or more of our total revenue during the year ended December 31, 2010: McKesson Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cardinal Health, Inc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AmerisourceBergen Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Percentage of Total Revenue 2010 28% 24% 12% No other country, or single customer, generated over 10% of our total product net sales. We currently promote our pharmaceutical products to physicians, hospitals, pharmacies and wholesalers through our own sales force and sell through wholesalers. In some limited markets, we additionally sell directly to physicians, hospitals and large drug store chains and we sell through distributors in countries where we do not have our own sales staff. As part of our marketing program for pharmaceuticals, we use direct mailings, advertise in trade and medical periodicals, exhibit products at medical conventions and sponsor medical education symposia. Competition Competitive Landscape for Products and Products in Development Our competitors include specialty and large pharmaceutical companies, biotechnology companies, OTC companies, academic and other research and development institutions and generic manufacturers, both in the U.S., Canada and abroad. The dermatology competitive landscape is highly fragmented, with a large number of mid-size and smaller companies competing in both the prescription sector and the OTC and cosmeceutical sectors. Our competitors are pursuing the development of pharmaceuticals and OTC products that target the same diseases and conditions that we are targeting in neurology, dermatology and other therapeutic areas. We sell a broad range of products, and competitive factors vary by product line and geographic area in which the products are sold. Ezogabine/retigabine Our competitors are developing products and product candidates that would compete with ezogabine/retigabine. The success of any of our competitors’ products or product candidates could adversely affect our expected revenues for ezogabine/retigabine, if approved. In addition, there are several generic compounds that currently compete in this market, which could limit the success of ezogabine/retigabine. Generic Competition We also face increased competition from manufacturers of generic pharmaceutical products when patents covering certain of our currently marketed products expire or are successfully challenged. Generic versions are generally significantly less expensive than branded versions, and, where available, may be required in preference to the branded version under third-party reimbursement programs, or substituted by pharmacies. If competitors introduce new products, delivery systems or processes with therapeutic or cost advantages, our products can be subject to progressive price reductions or decreased volume of sales, or both. Most new products that we introduce must compete with other products already on the market or products that are later developed by competitors. Manufacturers of generic pharmaceuticals typically invest far less in research and development than research-based pharmaceutical companies and therefore can price their products significantly lower than branded products. Accordingly, when a branded product loses its market exclusivity, it normally faces intense price competition from generic forms of the product. To successfully compete for business with managed care and pharmacy benefits management organizations, we must often demonstrate that our products offer not only medical benefits but also cost advantages as compared with other forms of care. 11 We have two significant products, Cesamet(cid:4) and Zovirax(cid:4), which do not currently have generic competition and are not protected by patent or regulatory exclusivity. Cardizem(cid:4) CD faces many generic competitors on the majority of the available SKUs; however to date, the Cardizem(cid:4) CD 360mg SKU has not faced a generic competitor. As of the present date, Sun Pharmaceuticals’ ANDA authorizing marketing of its 360 mg dosage formulation of diltiazem hydrochloride extended release capsules corresponding to Cardizem(cid:4) CD has not been approved. Biovail Laboratories International SRL and the Company recently received a Paragraph IV Notice from Actavis, Inc. (‘‘Actavis’’) dated February 9, 2011 in regard to 360 mg dosage diltiazem hydrochloride extended release capsules corresponding to Cardizem(cid:4) CD. Actavis subsequently converted its Paragraph IV filing to a Paragraph III filing and will not launch until after the expiration of the last patent covering Cardizem(cid:4) CD expires in August 2012. On October 12, 2007, Valeant settled a patent infringement lawsuit with Kali Laboratories, Inc. (‘‘Kali’’) regarding Kali’s submission of an ANDA with the FDA seeking approval for a generic version of Diastat(cid:4) (a diazepam rectal gel). Under the terms of this settlement, Valeant agreed to allow Barr Laboratories (now Teva Pharmaceuticals (‘‘Teva’’)), with whom Kali has a marketing agreement, to introduce a generic version of Diastat(cid:4) and Diastat(cid:4) AcuDial(cid:5) on or after September 1, 2010, or earlier under certain circumstances. Pursuant to this agreement, Teva launched a generic competitor to Diastat(cid:4) and Diastat(cid:4) AcuDial(cid:5) in September 2010. Manufacturing We currently operate 13 manufacturing plants worldwide. All of our manufacturing facilities that require certification from the FDA, TPD or foreign agencies have obtained such approval. We also subcontract the manufacturing of certain of our products, including products manufactured under the rights acquired from other pharmaceutical companies. Generally, acquired products continue to be produced for a specific period of time by the selling company. During that time, we integrate the products into our own manufacturing facilities or initiate toll manufacturing agreements with third parties. We estimate that products representing approximately 40% of our product sales are produced by third party manufacturers under toll manufacturing arrangements. The principal raw materials used by us for our various products are purchased in the open market. Most of these materials are available from several sources. Employees As of December 31, 2010, we had approximately 4,300 employees. These employees included approximately 2,400 in production, 1,100 in sales and marketing, 300 in research and development and 500 in general and administrative positions. Collective bargaining exists for some employees in a number of markets. We currently consider our relations with our employees to be good and have not experienced any work stoppages, slowdowns or other serious labor problems that have materially impeded our business operations. Product Liability Insurance We have product liability insurance to cover damages resulting from the use of our products. We have in place clinical trial insurance in the major markets where we conduct clinical trials. Seasonality of Business Our results of operations have not been materially impacted by seasonality. Geographic Areas A significant portion of our revenues are generated from operations or otherwise earned outside the U.S. and Canada. All of our foreign operations are subject to risks inherent in conducting business abroad, including price and currency exchange controls, fluctuations in the relative values of currencies, political instability and restrictive governmental actions including possible nationalization or expropriation. Changes in the relative 12 values of currencies may materially affect our results of operations. For a discussion of these risks, see Item 1A., Risk Factors in this Form 10-K. See Note 26 of notes to consolidated financial statements in Item 15 of this Form 10-K for detailed information regarding revenues by geographic area. A significant portion of our revenue and income is earned in Barbados, which has low domestic tax rates. See Item 1A., Risk Factors in this Form 10-K. Available Information Our Internet address is www.valeant.com. We post links on our website to the following filings as soon as reasonably practicable after they are electronically filed or furnished to the SEC: annual reports on Form 10-K, quarterly reports on Form 10-Q, current reports on Form 8-K and any amendment to those reports filed or furnished pursuant to Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended. All such filings are available through our website free of charge. The information on our Internet website is not incorporated by reference into this Form 10-K or our other securities filings and is not a part of such filings. We are also required to file reports and other information with the securities commissions in all provinces in Canada. You are invited to read and copy any reports, statements or other information, other than confidential filings, that we file with the provincial securities commissions. These filings are also electronically available from the Canadian System for Electronic Document Analysis and Retrieval (‘‘SEDAR’’) (http://www.sedar.com), the Canadian equivalent of the SEC’s electronic document gathering and retrieval system. Our filings may also be read and copied at the SEC’s Public Reference Room at 100 F. Street, NE, Washington, DC 20549. Information on the operation of the Public Reference Room may be obtained by calling the SEC at 1-800-SEC-0330. The SEC also maintains an Internet website at www.sec.gov that contains reports, proxy and information statements, and other information regarding issuers, including us, that file electronically with the SEC. Item 1A. Risk Factors The Company’s business, operations and financial condition are subject to various risks and uncertainties. You should carefully consider the risks and uncertainties described below, together with all of the other information in this Form 10-K, including those risks set forth under the heading entitled ‘‘Forward-Looking Statements’’, and in other documents that the Company files with the SEC and the CSA, before making any investment decision with respect to its securities. If any of the risks or uncertainties actually occur or develop, the Company’s business, financial condition, results of operations and future growth prospects could change. Under these circumstances, the market value of the Company’s securities could decline, and you could lose all or part of your investment in the Company’s securities. We operate in an extremely competitive industry. If competitors develop or acquire more effective or less costly drugs for our target indications, our business could be seriously harmed. Many of our competitors, particularly large pharmaceutical companies, have substantially greater financial, technical and human resources than we do. Many of our competitors spend significantly more on research and development related activities than we do. Others may succeed in developing or acquiring products that are more effective than those currently marketed or proposed for development by us. In addition, academic institutions, government agencies and other public and private organizations conducting research may seek patent protection with respect to potentially competitive products. They may also establish exclusive collaborative or licensing relationships with our competitors. The failure to integrate successfully the businesses of Valeant and Biovail in the expected time frame could adversely affect the Company’s future results. The success of the combined Company going forward will depend, in large part, on the ability of the Company to realize the anticipated benefits, including cost savings, from combining the businesses of Valeant and Biovail. To realize these anticipated benefits, the businesses of Valeant and Biovail must be successfully integrated. While the integration process is well underway, it is complex and time-consuming. The failure to 13 integrate successfully and to manage successfully the challenges presented by the integration process would result in the Company not achieving the anticipated benefits of the Merger. We cannot assure you that the Company will be successful or that the Company will realize the expected operating efficiencies, synergies, cost savings, revenue enhancements and other benefits anticipated from the Merger. Potential difficulties that may be encountered in the integration process include the following: • integrating the research and development, manufacturing, distribution, sales, marketing and promotion activities and financial and information technology systems of Valeant and Biovail; • challenges and difficulties associated with managing the larger, more complex, combined business; • identifying and eliminating redundant and underperforming operations and assets; • consolidating sales and marketing operations and corporate and administrative infrastructures; • conforming standards, controls, procedures and policies, business cultures and compensation structures between the companies; • integrating personnel from the two companies while maintaining focus on producing and delivering consistent, high quality products; • distracting employees from operations; • retaining existing customers and attracting new customers; • coordinating geographically dispersed organizations; • managing inefficiencies associated with integrating the operations of the Company; • complying with the terms of the corporate integrity agreement dated September 11, 2009, between the Office of Inspector General of the Department of Health and Human Services and Biovail (the ‘‘CIA’’); • the ability of the Company to deliver on its strategy going forward; and • making any necessary modifications to operating control standards to comply with the Sarbanes-Oxley thereunder and National Act of 2002 and Instrument 52-107 Certification of Disclosure in Issuers’ Annual Report and Interim Filings. regulations promulgated rules and the The Company estimates that it will incur costs in the range of $135 million and $180 million in connection with its integration initiatives; however, there are many factors beyond its control that could affect the total amount or the timing of the integration expenses. The Company’s effective tax rates may increase. The Company has operations in various countries that have differing tax laws and rates. The Company’s tax reporting is supported by current domestic tax laws in the countries in which the Company operates and the application of tax treaties between the various countries in which the Company operates. The Company’s income tax reporting will be, and the historic tax reporting of each of Valeant and Biovail is, subject to audit by domestic and foreign authorities. The Company’s effective tax rate may change from year to year based on changes in the mix of activities and income allocated or earned among the different jurisdictions in which it operates; changes in tax laws in these jurisdictions; changes in the tax treaties between various countries in which it operates; changes in its eligibility for benefits under those tax treaties; and changes in the estimated values of deferred tax assets and liabilities. Such changes could result in a substantial increase in the effective tax rate on all or a portion of the Company’s income. The Company’s provision for income taxes is based on certain estimates and assumptions made by management. The Company’s consolidated income tax rate is affected by the amount of net income earned in its various operating jurisdictions, the availability of benefits under tax treaties, and the rates of taxes payable in respect of that income. The Company enters into many transactions and arrangements in the ordinary course of business in respect of which the tax treatment is not entirely certain. The Company therefore makes estimates and judgments based on its knowledge and understanding of applicable tax laws and tax treaties, and the 14 application of those tax laws and tax treaties to its business, in determining its consolidated tax provision. For example, certain countries could seek to tax a greater share of income than will be provided for by the Company. The final outcome of any audits of the Company by taxation authorities may differ from the estimates and assumptions the Company may use in determining its consolidated tax provisions and accruals. This could result in a material adverse effect on the Company’s consolidated income tax provision, financial condition and the net income for the period in which such determinations are made. The Company’s deferred tax liabilities, deferred tax assets and any related valuation allowances are affected by events and transactions arising in the ordinary course of business, acquisitions of assets and businesses, and non-recurring items. The assessment of the appropriate amount of a valuation allowance against the deferred tax assets is dependent upon several factors, including estimates of the realization of deferred income tax assets, which realization will be primarily based on forecasts of future taxable income. Significant judgment is applied to determine the appropriate amount of valuation allowance to record. Changes in the amount of any valuation allowance required could materially increase or decrease the Company’s provision for income taxes in a given period. The Company has incurred significant indebtedness, which indebtedness may restrict the manner in which the Company conducts business and limit the Company’s ability to implement elements of its growth strategy. The Company has incurred significant indebtedness in connection with and following the Merger. We may also incur additional long-term debt and working capital lines of credit to meet future financing needs which, subject to certain restrictions under our indebtedness, including the Credit Facilities and the Senior Notes, would increase our total debt. This indebtedness may restrict the manner in which the Company conducts business and limit the Company’s ability to implement elements of its growth strategy, including with respect to: • limitations on our ability to obtain additional debt financing; • instances in which we are unable to meet the financial covenants contained in our debt agreements or to generate cash sufficient to make required debt payments, which circumstances would have the potential of resulting in the acceleration of the maturity of some or all of our outstanding indebtedness; • the allocation of a substantial portion of our cash flow from operations to service our debt, thus reducing the amount of our cash flow available for other purposes; • requiring us to issue debt or equity securities or to sell some of our core assets, possibly on unfavorable terms, to meet payment obligations; • compromising our flexibility to plan for, or react to, competitive challenges in our business; • the possibility that we are put at a competitive disadvantage relative to competitors that do not have as much debt as us, and competitors that may be in a more favorable position to access additional capital resources; and • limitations on our ability to execute business development activities to support our strategies. We may be unable to identify, acquire or integrate acquisition targets successfully. Part of our business strategy includes acquiring and integrating complementary businesses, products, technologies or other assets, and forming strategic alliances, joint ventures and other business combinations, to help drive future growth. We may also in-license new products or compounds. Acquisitions or similar arrangements may be complex, time consuming and expensive. We may not consummate some negotiations for acquisitions or other arrangements, which could result in significant diversion of management and other employee time, as well as substantial out-of-pocket costs. If the acquisition is consummated, the integration of the acquired business, product or other assets into our company may be also be complex and time-consuming and, if such businesses, products and assets are not successfully integrated, we may not achieve the anticipated benefits, cost-savings or growth opportunities. Furthermore, these acquisitions and other arrangements, even if successfully integrated, may fail to further our business strategy as anticipated, expose us to increased competition or challenges with respect to our products or geographic markets, and expose us to additional liabilities associated with an acquired business, product, technology or other asset or arrangement. Any one of 15 these challenges or risks could impair our ability to realize any benefit from our acquisition or arrangement after we have expended resources on them. Obtaining necessary government approvals is time consuming and not assured. The FDA and TPD approval must be obtained in the U.S. and Canada, respectively, and approval must be obtained from comparable agencies in other countries prior to marketing or manufacturing new pharmaceutical products for use by humans. Obtaining FDA, TPD and other regulatory approval for new products and manufacturing processes can take a number of years and involves the expenditure of substantial resources. Even if such products appear promising in large-scale Phase 3 clinical trials, regulatory approval may not be achieved and no assurance can be given that we will obtain approval in the U.S., Canada or any other country. Nor can any assurance be given that if such approval is secured, the approved labeling will not have significant labeling limitations or that this approval may include limitations on the indications for which we can market a product or onerous risk management programs. Our marketed drugs will be subject to ongoing regulatory review. Following initial regulatory approval of any drugs we or our partners may develop, we will be subject to continuing regulatory review by the FDA, the TPD and other regulatory authorities in countries where our products are marketed or intended to be marketed, including the review of adverse drug events and clinical results that are reported after product candidates become commercially available. The manufacturing, labeling, packaging, storage, distribution, advertising, promotion, reporting and recordkeeping related to the product will also be subject to extensive ongoing regulatory requirements. If we fail to comply with U.S. and Canadian regulatory requirements and those in other countries where our products are sold, we could lose our marketing approvals or be subject to fines or other sanctions. In addition, incidents of adverse drug reactions (‘‘ADRs’’), unintended side effects or misuse relating to our products could result in additional regulatory controls or restrictions, or even lead to withdrawal of a product from the market. As a condition to granting marketing approval of a product, the FDA and TPD may require a company to conduct additional clinical trials, the results of which could result in the subsequent loss of marketing approval, changes in product labeling or new or increased concerns about side effects or efficacy of a product. Our approved products may not achieve or maintain expected levels of market acceptance, which could have a material adverse effect on our business, financial condition and results of operations. Even if we are able to obtain and maintain regulatory approvals for our new pharmaceutical products, generic or branded, the success of these products is dependent upon achieving and maintaining market acceptance. Commercializing products is time consuming, expensive and unpredictable. There can be no assurance that we will be able to, either by ourselves or in collaboration with our partners or through our licensees, successfully commercialize new products or gain market acceptance for such products. New product candidates that appear promising in development may fail to reach the market or may have only limited or no commercial success. Levels of market acceptance for our new products could be impacted by several factors, many of which are not within our control, including but not limited to the: • safety, efficacy, convenience and cost-effectiveness of our products compared to products of our competitors; • scope of approved uses and marketing approval; • timing of market approvals and market entry; • availability of alternative products from our competitors; • acceptance of the price of our products; and • ability to market our products effectively at the retail level or in the appropriate setting of care. Further, the discovery of significant problems with a product similar to one of our products that implicate (or are perceived to implicate) an entire class of products could have an adverse effect on sales of the affected products. Accordingly, new data about our products, or products similar to our products, could negatively impact 16 demand for our products due to real or perceived side effects or uncertainty regarding efficacy and, in some cases, could result in product withdrawal. We will not be able to commercialize our pipeline products if preclinical studies do not produce successful results or if clinical trials do not demonstrate safety and efficacy in humans. The Company and its development partners, as applicable, conduct extensive preclinical studies and clinical trials to demonstrate the safety and efficacy in humans of our pipeline products in order to obtain regulatory approval for the sale of our pipeline products. Preclinical studies and clinical trials are expensive, can take many years and have uncertain outcomes. If we or our third-party manufacturers are unable to manufacture our products or the manufacturing process is interrupted due to failure to comply with regulations or for other reasons, the interruption of the manufacture of our products could adversely affect our business. Other manufacturing difficulties or delays may also adversely affect our business, financial condition and results of operations. Our manufacturing facilities and those of our contract manufacturers must be inspected and found to be in full compliance with current good manufacturing (‘‘cGMP’’) or similar standards before approval for marketing. Our failure or that of our contract manufacturers to comply with cGMP regulations or similar regulations outside of the U.S. can result in enforcement action by the FDA or its foreign counterparts, including, among other things, warning letters, fines, injunctions, civil or criminal penalties, recall or seizure of products, total or partial suspension of production, suspension or withdrawal of regulatory approval for approved or in-market products, refusal of the government to renew marketing applications or approve pending applications or supplements, suspension of ongoing clinical trials, imposition of new manufacturing requirements, closure of facilities and criminal prosecution. Our manufacturing and other processes use complicated and sophisticated equipment, which sometimes requires a significant amount of time to obtain and install. Manufacturing complexity, testing requirements and safety and security processes combine to increase the overall difficulty of manufacturing these products and resolving manufacturing problems that we may encounter. Although we endeavor to properly maintain our equipment, including through on-site quality control and experienced manufacturing supervision, and have key spare parts on hand, our business could suffer if certain manufacturing or other equipment, or all or a portion of our facilities, were to become inoperable for a period of time. This could occur for various reasons, including catastrophic events, such as hurricanes, earthquakes or other natural disasters, explosions, environmental accidents, pandemics, quarantine, equipment failures or delays in obtaining components or replacements, construction delays or defects and other events, both within and outside of our control. We could experience substantial production delays in the event of any such occurrence until we build or locate replacement equipment or a replacement facility, as applicable, and seek to obtain necessary regulatory approvals for such replacement. Any interruption in our manufacture of products could have a material adverse effect on our business, financial condition and results of operations and could cause the market value of our common shares to decline. Our dependence upon others to manufacture our products may adversely affect our profit margins and our ability to develop and obtain approval for our products on a timely and competitive basis, if at all. In addition, delays or difficulties by us or with our contract manufacturers in producing, packaging, or distributing our products could adversely affect the sales of our current products or introduction of other products. If we are unable to obtain components or raw materials, or products supplied by third parties, our ability to manufacture and deliver our products to the market would be impeded, which could have a material adverse effect on our business, financial condition and results of operations. Some components and raw materials used in our manufactured products, and some products sold by us, are currently available only from one or a limited number of domestic or foreign suppliers. In the event an existing supplier becomes unavailable through business interruption or financial insolvency or loses its regulatory status as an approved source or we are unable to renew current supply agreements when such agreements expire and we do not have a second supplier, we may be unable to obtain the required components, raw materials or products on a timely basis or at commercially reasonable prices. A prolonged interruption in the supply of a single-sourced raw material, including the active pharmaceutical ingredient, could have a material adverse effect 17 on our business, financial condition and results of operations, and the market value of our common shares could decline. Disruptions of delivery of our products could adversely impact our business, financial condition and results of operations. The supply of our products to our customers is subject to and dependent upon the use of transportation services. Disruption of transportation services could adversely impact our financial results. We have entered into distribution agreements with other companies to distribute certain of our products at supply prices based on net sales. Declines in the pricing and/or volume, over which we have no control, of such products, and therefore the amounts paid to us, may have a material adverse effect on our business and results of operations. Our portfolio of generic products is the subject of various agreements, pursuant to which we manufacture and sell generic products to other companies, which distribute such products at a supply price typically based on net sales. These companies make all distribution and pricing decisions independently of us. If the pricing or volume of such generic products declines, our revenues would be adversely impacted which could have a material adverse effect on our business and results of operations and could cause the market value of our common shares to decline. Our marketing, promotional and pricing practices, as well as the manner in which sales forces interact with purchasers, prescribers and patients, are subject to extensive regulation and any material failure to comply could result in significant sanctions against the Company. The marketing, promotional, and pricing practices of pharmaceutical companies, as well as the manner in which companies, in-house or third-party sales forces interact with purchasers, prescribers, and patients, are subject to extensive regulation, enforcement of which may result in the imposition of civil and/or criminal penalties, injunctions, and/or limitations on marketing practice for our products. Many companies, including the Company, have been the subject of claims related to these practices asserted by federal authorities. These claims have resulted in fines and other consequences to the Company. We are now operating under a CIA that requires us to maintain a comprehensive compliance program governing our sales, marketing and government pricing and contracting functions. Material failures to comply with the CIA could result in significant sanctions to the Company, including monetary penalties and exclusion from federal health care programs. Companies may not promote drugs for ‘‘off-label’’ uses — that is, uses that are not described in the product’s labeling and that differ from those approved by the FDA, TPD or other applicable regulatory agencies. A company that is found to have improperly promoted off-label uses may be subject to significant liability, including civil and administrative remedies as well as criminal sanctions. In addition, management’s attention could be diverted from our business operations and our reputation could be damaged. Products representing a significant amount of our revenue are not protected by patent or data exclusivity rights. A significant amount of the products we sell have no meaningful exclusivity protection via patent or data exclusivity rights. These products represent a significant amount of our revenues. Without exclusivity protection, competitors face fewer barriers in introducing competing products. The introduction of competing products could adversely affect our results of operations and financial condition. Our business, financial condition and results of operations are subject to risks arising from the international scope of our operations. We conduct a significant portion of our business outside the U.S. and Canada. We sell our pharmaceutical products in many countries around the world. All of our foreign operations are subject to risks inherent in conducting business abroad, including possible nationalization or expropriation, price and currency exchange controls, fluctuations in the relative values of currencies, political instability and restrictive governmental actions. 18 Due to the large portion of our business conducted outside the United States, we have significant foreign currency risk. We sell products in many countries that are susceptible to significant foreign currency risk. In some of these markets we sell products for U.S. dollars. While this eliminates our direct currency risk in such markets, it increases our risk that we could lose market share to competitors because if a local currency is devalued significantly, it becomes more expensive for customers in that market to purchase our products in U.S. dollars. The international scope of our operations may also lead to volatile financial results and difficulties in managing our operations. We also face foreign currency exposure on the translation of our operations in Canada from Canadian dollars to U.S. dollars. Where possible, we manage foreign currency risk by managing same currency assets in relation to same currency liabilities, and same currency revenue in relation to same currency expenses. As a result, both favorable and unfavorable foreign currency impacts to our foreign currency-denominated operating expenses are mitigated to a certain extent by the natural, opposite impact on our foreign currency-denominated revenue. We also have additional foreign currency exposure related to the Polish zloty (and other Eastern European currencies), the Mexican peso, the Brazilian real and the Australian dollar. The Company must continue to retain, motivate and recruit executives and other key employees, and failure to do so could negatively affect the Company. The Company must continue to retain, motivate and recruit executives and other key employees. A failure by the Company to retain and motivate executives and other key employees could have an adverse impact on the Company’s business. The general business and economic conditions in the U.S., Canada and other countries in which we conduct business could have a material adverse impact on our liquidity and capital resources, revenues and operating results. We may be impacted by general economic conditions and factors over which we have no control, such as changes in inflation, interest rates and foreign currency rates, lack of liquidity in certain markets and volatility in capital markets. Similarly, adverse economic conditions impacting our customers could cause purchases of our products to decline, which could adversely affect our revenues and operating results. Moreover, our projected revenues and operating results are based on assumptions concerning certain levels of customer spending. Any failure to attain our projected revenues and operating results as a result of adverse economic or market conditions could have a material adverse effect on our business and result in a decline in the price of our common stock. We are exposed to risks related to interest rates. The primary objective of investing our excess cash is the protection of principal and, accordingly, we invest in investment grade securities with varying maturities, but typically less than one year. Our Credit Facility bears interest based on U.S. dollar London Interbank Offering Rates, or U.S. Prime Rate, or Federal Funds effective rate. Thus, a change in the short-term interest rate environment could have a material adverse effect on our results of operations, financial condition or cash flows. As of December 31, 2010, we do not have any outstanding interest rate swap contracts. We are involved in various legal proceedings that could adversely affect us. We are involved in several legal proceedings, including those described in Note 24 of notes to consolidated financial statements in Item 15 of this Form 10-K. Defending against claims and any unfavorable legal decisions, settlements or orders could have a material adverse effect on us. If our products cause, or are alleged to cause, serious or widespread personal injury, we may have to withdraw those products from the market and/or incur significant costs, including payment of substantial sums in damages, and we may be subject to exposure relating to product liability claims. We face an inherent business risk of exposure to significant product liability and other claims in the event that the use of our products caused, or is alleged to have caused, adverse effects. Furthermore, our products may cause, or may appear to have caused, adverse side effects (including death) or potentially dangerous drug 19 interactions that we may not learn about or understand fully until the drug has been administered to patients for some time. The withdrawal of a product following complaints and/or incurring significant costs, including the requirement to pay substantial damages in personal injury cases or product liability cases, could have a material adverse effect on our business, financial condition and results of operations and could cause the market value of our common shares to decline. Our product liability insurance coverage may not be sufficient to cover our claims and we may not be able to obtain sufficient coverage at a reasonable cost in the future. We may become involved in infringement actions which are uncertain, costly and time-consuming and could have a material adverse effect on our business, results of operations, financial condition and cash flows. The pharmaceutical industry historically has generated substantial litigation concerning the manufacture, use and sale of products and we expect this litigation activity to continue. As a result, we expect that patents related to our products will be routinely challenged, and our patents may not be upheld. In order to protect or enforce patent rights, we may initiate litigation against third parties. If we are not successful in defending an attack on our patents and maintaining exclusive rights to market one or more of our major products still under patent protection, we could lose a significant portion of sales in a very short period. We may also become subject to infringement claims by third parties and may have to defend against charges that we violated patents or the proprietary rights of third parties. If we infringe the intellectual property rights of others, we could lose our right to develop, manufacture or sell products, including our generic products, or could be required to pay monetary damages or royalties to license proprietary rights from third parties. The outcomes of infringement action are uncertain and infringement actions are costly and divert technical and management personnel from their normal responsibilities. We are subject to various laws and regulations, including ‘‘fraud and abuse’’ laws and anti-bribery laws, and a failure to comply with such laws and regulations or prevail in any litigation related to noncompliance could harm our business. Pharmaceutical and biotechnology companies have faced lawsuits and investigations pertaining to violations of health care ‘‘fraud and abuse’’ laws, such as the federal False Claims Act, the federal Anti-Kickback Statute, the U.S. Foreign Corrupt Practices Act (‘‘FCPA’’) and other state and federal laws and regulations. We also face increasingly strict data privacy and security laws in the U.S. and in other countries, the violation of which could result in fines and other sanctions. Increasingly, states require pharmaceutical companies to have comprehensive compliance programs and to disclose certain payments made to healthcare providers or funds spent on marketing and promotion of drug products. If we are in violation of any of these requirements or any such actions are instituted against us, and we are not successful in defending ourselves or asserting our rights, those actions could have a significant impact on our business, including the imposition of significant fines, exclusion from federal healthcare programs or other sanctions. The FCPA and similar worldwide anti-bribery laws generally prohibit companies and their intermediaries from making improper payments to officials for the purpose of obtaining or retaining business. Our policies mandate compliance with these anti-bribery laws. We operate in many parts of the world that have experienced governmental corruption to some degree and in certain circumstances, strict compliance with anti-bribery laws may conflict with local customs and practices or may require us to interact with doctors and hospitals, some of which may be state controlled, in a manner that is different than in the U.S. and Canada. We cannot assure you that our internal control policies and procedures always will protect us from reckless or criminal acts committed by our employees or agents. Violations of these laws, or allegations of such violations, could disrupt our business and result in a material adverse effect on our financial condition, results of operations and cash flows. Our failure to comply with applicable environmental laws and regulations worldwide could have a material adverse effect on our business, financial condition and results of operations. We are subject to laws and regulations concerning the environment, safety matters, regulation of chemicals and product safety in the countries where we manufacture and sell our products or otherwise operate our business. These requirements include regulation of the handling, manufacture, transportation, use and disposal of materials, including the discharge of pollutants into the environment. In the normal course of our business, hazardous substances may be released into the environment, which could cause environmental or property damage or personal injuries, and which could subject us to remediation obligations regarding contaminated soil 20 and groundwater or potential liability for damage claims. Under certain laws, we may be required to remediate contamination at certain of our properties regardless of whether the contamination was caused by us or by previous occupants of the property or by others. In recent years, the operations of all companies have become subject to increasingly stringent legislation and regulation related to occupational safety and health, product registration and environmental protection. Such legislation and regulations are complex and constantly changing, and future changes in laws or regulations may require us to install additional controls for certain of our emission sources, to undertake changes in our manufacturing processes or to remediate soil or groundwater contamination at facilities where such cleanup is not currently required. We are exposed to risks if we are unable to comply with laws and future changes to laws affecting public companies, including the Sarbanes-Oxley Act of 2002 (‘‘SOX’’), and also to increased costs associated with complying with such laws. Any future changes to the laws and regulations affecting public companies, as well as compliance with existing provisions of SOX in the U.S. and Part XXIII.1 of the Securities Act (Ontario), R.S.O. 1990, c. S.5 (the ‘‘Ontario Securities Act’’) and related rules and applicable stock exchange rules and regulations, may cause us to incur increased costs as we evaluate the implications of new rules and respond to new requirements. Delays, or a failure to comply with any laws, rules and regulations that apply to us, could result in enforcement actions, the assessment of other penalties and civil suits. New laws and regulations could make it more expensive for us under indemnities we provide to our officers and directors and could make it more difficult for us to obtain certain types of insurance, including liability insurance for directors and officers; as such, we may be forced to accept reduced policy limits and coverage or incur substantially higher costs to obtain the same or similar coverage. The impact of these events could also make it more difficult for us to attract and retain qualified persons to serve on the board of directors or as officers. We are required annually to review and report on the effectiveness of our internal control over financial reporting in accordance with applicable securities laws. Our registered public accounting firm is also required to report on the effectiveness of our internal control over financial reporting. If we fail to maintain effective internal controls over our financial reporting, there is the possibility of errors or omissions occurring or misrepresentations in our disclosures which could have a material adverse effect on our business and financial condition and the value of our common shares. Legislative or regulatory reform of the healthcare system may affect our ability to sell our products profitably and could adversely affect our business. In the U.S. and certain foreign jurisdictions, there have been a number of legislative and regulatory proposals to change the healthcare system in ways that could impact our ability to sell our products profitably. On March 23, 2010, President Obama signed into law the Patient Protection and Affordable Care Act (‘‘PPACA’’), which includes a number of health care reform provisions and requires most U.S. citizens to have health insurance. Effective January 1, 2010, the new law increased the minimum Medicaid drug rebates for pharmaceutical companies, expanded the 340B drug discount program, and made changes to affect the Medicare Part D coverage gap, or ‘‘donut hole.’’ The law also revised the definition of ‘‘average manufacturer price’’ for reporting purposes, which may increase the amount of our Medicaid drug rebates to states. Beginning in 2011, the new law imposes a significant annual fee on companies that manufacture or import branded prescription drug products. Substantial new provisions affecting compliance also have been added, which may require us to modify our business practices with health care practitioners. A variety of federal and state agencies are responsible for implementing the law, including through the issuance of rules, regulations or guidance that materially affect our business. Various legal challenges have been filed against the law, with some lower courts reaching conflicting decisions, and we cannot predict at this time what impact these challenges will have on our business. Item 1B. Unresolved Staff Comments None. 21 Item 2. Properties We believe that we have sufficient facilities to conduct our operations during 2011. The following table lists the location, use, size and ownership interest of our principal properties: Location Purpose Mississauga, Ontario, Canada . . . . . . Corporate Headquarters Aliso Viejo, California . . . . . . . . . . . . Corporate offices and administration Bridgewater, New Jersey . . . . . . . . . . Administration Christ Church, Barbados . . . . . . . . . . Commercial, IP and strategic planning U.S. Dermatology Petaluma, California . . . . . . . . . . . . . Offices and laboratories U.S. Neurology and Other Chantilly, Virginia . . . . . . . . . . . . . . . Research and development services Owned or Leased Approximate Square Footage Leased Leased Leased Owned 79,000(1) 110,000(1) 110,000 23,000 Leased 50,000 Leased 80,000(2) Canada and Australia Montreal, Quebec, Canada . . . . . . . . Offices, manufacturing and warehouse facility Owned Steinbach, Manitoba, Canada . . . . . . . Offices, manufacturing and warehouse facility Owned Branded Generics — Latin America Mexico City, Mexico . . . . . . . . . . . . . Offices and manufacturing facility Mexico City, Mexico . . . . . . . . . . . . . Offices and manufacturing facility San Juan del Rio, Mexico . . . . . . . . . Manufacturing facility Indaiatuba, Brazil . . . . . . . . . . . . . . . Manufacturing facility Branded Generics — Europe Rzeszow, Poland . . . . . . . . . . . . . . . . Offices and manufacturing facility Warszawa (Marynarska), Poland . . . . . Offices 94,000 250,000 102,000 211,000 96,000 165,000 Leased Owned Owned Owned Owned Leased 447,000 124,000 (1) In the first half of 2011, we plan to vacate our corporate headquarters in Mississauga and our corporate offices in Aliso Viejo and relocate to other smaller leased facilities. (2) Following the completion of certain activities associated with the termination of certain of our research and development projects, we intend to vacate our leased facility in Chantilly, Virginia. We believe our facilities are in satisfactory condition and are suitable for their intended use, although some limited investments to improve our manufacturing and other related facilities are contemplated, based on the needs and requirements of our business. Item 3. Legal Proceedings See Note 24 of notes to consolidated financial statements in Item 15 of this Form 10-K, which is incorporated by reference herein. Item 4. (Removed and Reserved) Not applicable. 22 Item 5. Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of PART II Equity Securities Market Information Our common shares are traded on the New York Stock Exchange (‘‘NYSE’’) and on the Toronto Stock Exchange (‘‘TSX’’) under the symbol ‘‘VRX’’. The following table sets forth the high and low per share sales prices for our common shares on the NYSE and TSX for the periods indicated. 2009 First quarter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Second quarter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Third quarter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Fourth quarter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2010 First quarter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Second quarter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Third quarter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Fourth quarter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Source: NYSEnet, TSX Historical Data Access Market Price Volatility of Common Shares NYSE TSX High $ Low $ High C$ Low C$ 12.15 13.75 15.50 15.49 16.97 19.81 27.74 30.80 9.41 9.26 12.14 12.91 13.64 13.66 18.07 24.06 14.53 15.90 16.59 16.55 17.26 20.87 28.50 30.85 10.30 10.90 13.45 13.78 14.60 14.34 19.25 24.41 Market prices for the securities of pharmaceutical and biotechnology companies, including our securities, have historically been highly volatile, and the market has from time to time experienced significant price and volume fluctuations that are unrelated to the operating performance of particular companies. Factors such as fluctuations in our operating results, the aftermath of public announcements by us, concern as to safety of drugs and general market conditions can have an adverse effect on the market price of our common shares and other securities. Holders The approximate number of holders of record of our common shares as of February 23, 2011 is 2,580. Performance Graph The following graph compares the cumulative total return on our common shares with the cumulative return on the S&P 500 Index, the TSX/S&P Composite Index and a 10-stock Custom Composite Index for the five years ended December 31, 2010, in all cases, assuming reinvestment of dividends. The Custom Composite Index consists of Allergan, Inc.; Cephalon, Inc.; Endo Pharmaceuticals Holdings Inc.; Forest Laboratories, Inc.; Gilead Sciences, Inc.; King Pharmaceuticals, Inc.; Medicis Pharmaceutical Corporation; Mylan Inc.; Perrigo Company; Shire Pharmaceuticals Group plc; and Watson Pharmaceuticals, Inc. 23 Valeant Pharmaceuticals International, Inc. Custom Composite Index S&P 500 Index S&P/TSX Composite Index x x x x x $180 $160 $140 $120 $100 x $80 $60 $40 $20 $0 Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 Dec-10 Valeant Pharmaceuticals International, Inc. S&P 500 Index S&P/TSX Composite Index Custom Composite Index Dec-05 100 100 100 100 Dec-06 91 114 115 113 Dec-07 63 118 123 124 Dec-08 51 72 80 105 Dec-09 79 89 104 126 Dec-10 169 101 119 154 24FEB201102010705 Dividends During 2009 and 2010, we declared dividends per common share as follows: Date Declared Dividend per Share Payment Date February 26, 2009 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . May 6, 2009 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . August 6, 2009 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . November 5, 2009 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . February 25, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . May 6, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . August 5, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . November 4, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Total . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $0.375 $ 0.09 $ 0.09 $ 0.09 $ 0.09 $0.095 $0.095 $ 1.00 $1.925 April 6, 2009 July 6, 2009 October 5, 2009 January 4, 2010 April 5, 2010 July 5, 2010 October 4, 2010 December 22, 2010 On November 4, 2010, our board of directors declared a special dividend of $1.00 (the ‘‘post-Merger special dividend’’) per common share, no par value. Shareholders of record as of the close of business on November 15, 2010 (the ‘‘record date’’) were entitled to receive the post-Merger special dividend on December 22, 2010. In connection with the post-Merger special dividend, we established a special dividend reinvestment plan under which eligible shareholders of record as of the record date could elect to reinvest the post-Merger special dividend (net of any applicable withholding tax) in additional common shares of the Company. Following the payment of the post-Merger special dividend, the special dividend reinvestment plan was terminated. The aggregate cash post-Merger special dividend paid was $297.6 million and we issued 72,283 additional shares to shareholders that elected to reinvest in additional common shares of the Company. While our board of directors will review our dividend policy from time to time, we currently do not intend to pay dividends in the foreseeable future. See Item 7. ‘‘Management’s Discussion and Analysis of Financial Condition and Results of Operation — Selected Financial Information — Cash Dividends’’, for additional details about our dividend payments. 24 Restrictions on Share Ownership by Non-Canadians There are no limitations under the laws of Canada or in our organizational documents on the right of foreigners to hold or vote securities of our Company, except that the Investment Canada Act (Canada) (the ‘‘Investment Canada Act’’) may require review and approval by the Minister of Industry (Canada) of certain acquisitions of ‘‘control’’ of our Company by a ‘‘non-Canadian’’. Investment Canada Act An acquisition of control of a Canadian business by a non-Canadian is either reviewable (a ‘‘Reviewable Transaction’’), in which case it is subject to both a reporting obligation and an approval process, or notifiable, in which case it is subject to only a post-closing reporting obligation. In the case of a Reviewable Transaction, the non-Canadian acquirer must submit an application for review with the prescribed information. The responsible Minister is then required to determine whether the Reviewable Transaction is likely to be of net benefit to Canada, taking into account the assessment factors specified in the Investment Canada Act and any written undertakings that may have been given by the non-Canadian acquirer. In March 2009, the Investment Canada Act was amended to provide that any investment by a non-Canadian in a Canadian business, even where control has not been acquired, can be reviewed on grounds of whether it may be injurious to national security. Where an investment is determined to be injurious to national security, Cabinet can prohibit closing or, if closed, can order the investor to divest control. Short of a prohibition or divestment order, Cabinet can impose terms or conditions on the investment or can require the investor to provide binding undertakings to remove the national security concern. Competition Act Part IX of the Competition Act (Canada) (the ‘‘Competition Act’’) requires that a pre-merger notification filing be submitted to the Commissioner of Competition (the ‘‘Commissioner’’) in respect of certain classes of merger transactions that exceed certain prescribed thresholds. If a proposed transaction exceeds such thresholds, subject to certain exceptions, the notification filing must be submitted to the Commissioner and the statutory waiting period must expire or be terminated early or waived by the Commissioner before the transaction can be completed. All mergers, regardless of whether they are subject to Part IX of the Competition Act, are subject to the substantive mergers provisions under Section 92 of the Competition Act. In particular, the Commissioner may challenge a transaction before the Competition Tribunal where the transaction prevents or lessens, or is likely to prevent or lessen, competition substantially in a market. The Commissioner may not make an application to the Competition Tribunal under Section 92 of the Competition Act more than one year after the merger has been substantially completed. Exchange Controls Canada has no system of exchange controls. There are no Canadian restrictions on the repatriation of capital or earnings of a Canadian public company to non-resident investors. There are no laws in Canada or exchange restrictions affecting the remittance of dividends, profits, interest, royalties and other payments to non-resident holders of our securities, except as discussed in ‘‘Taxation’’ below. Taxation Canadian Federal Income Taxation The following discussion is a summary of the principal Canadian federal income tax considerations generally applicable to a holder of our common shares who, at all relevant times, for purposes of the Income Tax Act (Canada) and the Income Tax Regulations (collectively, the ‘‘Canadian Tax Act’’) deals at arm’s-length with, and is not affiliated with, our Company, beneficially owns its common shares as capital property and does not use or hold and is not deemed to use or hold such common shares in carrying on a business in Canada and who, at all relevant times, for purposes of the application of the Canadian Tax Act and the Canada-U.S. Income Tax Convention (1980, as amended) (the ‘‘U.S. Treaty’’), is resident in the U.S., is not, and is not deemed to be, 25 resident in Canada and is eligible for benefits under the U.S. Treaty (a ‘‘U.S. Holder’’). Special rules, which are not discussed in the summary, may apply to a non-resident holder that is an insurer that carries on an insurance business in Canada and elsewhere or that is an ‘‘authorized foreign bank’’ as defined in the Canadian Tax Act. The U.S. Treaty includes limitation on benefits rules that restrict the ability of certain persons who are resident in the U.S. to claim any or all benefits under the U.S. Treaty. Furthermore, limited liability companies (‘‘LLCs’’) that are not taxed as corporations pursuant to the provisions of the U.S. Internal Revenue Code of 1986, as amended (the ‘‘Code’’) do not qualify as resident in the U.S. for purposes of the U.S. Treaty. Under the U.S. Treaty, a resident of the U.S. who is a member of such an LLC and is otherwise eligible for benefits under the U.S. Treaty may generally be entitled to claim benefits under the U.S. Treaty in respect of income, profits or gains derived through the LLC. Residents of the U.S. should consult their own tax advisors with respect to their eligibility for benefits under the U.S. Treaty, having regard to these rules. This summary is based upon the current provisions of the U.S. Treaty and the Canadian Tax Act and our understanding of the current administrative policies and assessing practices of the Canada Revenue Agency published in writing prior to the date hereof. This summary takes into account all specific proposals to amend the U.S. Treaty and the Canadian Tax Act publicly announced by or on behalf of the Minister of Finance (Canada) prior to the date hereof. This summary does not otherwise take into account or anticipate changes in law or administrative policies and assessing practices, whether by judicial, regulatory, administrative or legislative decision or action, nor does it take into account provincial, territorial or foreign tax legislation or considerations, which may differ from those discussed herein. This summary is of a general nature only and is not intended to be, nor should it be construed to be, legal or tax advice generally or to any particular holder. Holders should consult their own tax advisors with respect to their own particular circumstances. Gains on Disposition of Common Shares In general, a U.S. Holder will not be subject to tax under the Canadian Tax Act on capital gains arising on the disposition of such holder’s common shares unless the common shares are ‘‘taxable Canadian property’’ to the U.S. Holder and are not ‘‘treaty-protected property’’. As long as the common shares are then listed on a ‘‘designated stock exchange’’, which currently includes the NYSE and TSX, the common shares generally will not constitute taxable Canadian property of a U.S. Holder, unless (a) at any time during the 60-month period preceding the disposition, the U.S. Holder, persons not dealing at arm’s length with such U.S. Holder or the U.S. Holder together with all such persons, owned 25% or more of the issued shares of any class or series of the capital stock of the Company and more than 50% of the fair market value of the common shares was derived, directly or indirectly, from a combination of (i) real or immoveable property situated in Canada, (ii) ‘‘Canadian resource property’’ (as such term is defined in the Tax Act), (iii) ‘‘timber resource property’’ (as such terms are defined in the Tax Act), or (iv) options in respect of interests in, or for civil law rights in, any such properties whether or not the property exists, or (b) the common shares are otherwise deemed to be taxable Canadian property. Common shares will be treaty-protected property where the U.S. Holder is exempt from income tax under the Canadian Tax Act on the disposition of common shares because of the U.S. Treaty. Common shares owned by a U.S. Holder will generally be treaty-protected property where the value of the common shares is not derived principally from real property situated in Canada, as defined in the U.S. Treaty. 26 Dividends on Common Shares Dividends paid or credited on the common shares or deemed to be paid or credited on the common shares to a U.S. Holder that is the beneficial owner of such dividends will generally be subject to non-resident withholding tax under the Canadian Tax Act and the U.S. Treaty at the rate of (a) 5% of the amounts paid or credited if the U.S. Holder is a company that owns (or is deemed to own) at least 10% of our voting stock, or (b) 15% of the amounts paid or credited in all other cases. The rate of withholding under the Canadian Tax Act in respect of dividends paid to non-residents of Canada is 25% where no tax treaty applies. Securities Authorized for Issuance under Equity Compensation Plans Information required under this Item will be included in our definitive proxy statement for the 2011 Annual and Special Meeting of Shareholders expected to be filed with the SEC no later than 120 days after the end of the fiscal year covered by this Form 10-K (the ‘‘2011 Proxy Statement’’), and such required information is incorporated herein by reference. Purchases of Equity Securities by the Company and Affiliated Purchases On August 6, 2009, we announced that our board of directors had renewed the then share repurchase program. That share repurchase program terminated on August 11, 2010. No shares were repurchased under that program. On November 4, 2010, we announced that our board of directors approved a securities repurchase program (the ‘‘securities repurchase program’’), pursuant to which we may make purchases of our common shares, Convertible Notes and/or Senior Notes up to an aggregate maximum value of $1.5 billion, subject to any restrictions in our financing agreements and applicable law. Our board of directors also approved a sub-limit of up to 16 million common shares, representing approximately 10% of our public float (as estimated at the commencement of the securities repurchase program), to be purchased for cancellation under a normal course issuer bid through the facilities of the NSYE and TSX. We may initially make purchases under the securities repurchase program of up to 15 million common shares through the facilities of the NYSE, in accordance with applicable rules and guidelines. This represents approximately 5% of our issued and outstanding common shares as of November 4, 2010. Following additional filings and related approvals, we may also purchase common shares over the TSX. The program does not require us to repurchase a minimum number of securities, and the program may be modified, suspended or terminated at any time without prior notice. The securities repurchase program will terminate on November 7, 2011 or at such earlier time as we complete our purchases. Under the terms of our Credit Facility, our purchases under the securities repurchase program are subject to certain monetary thresholds, above which we require the consent of the lenders. The amount of securities to be purchased and the timing of purchases under the securities repurchase program may be subject to various factors, which may include the price of the securities, general market conditions, corporate and regulatory requirements, alternate investment opportunities and restrictions under the Company’s financing agreements. The securities to be repurchased will be funded using the Company’s cash resources. During the fourth quarter of 2010, we repurchased $126.3 million aggregate principal amount of our 5.375% Convertible Notes at an aggregate purchase price of $259.2 million (at an average price of $2.05 per $1.00 principal amount) and we repurchased 2,305,000 common shares at an average price of $26.08 per share, for total cash consideration of $60.1 million. 27 Set forth below is the information regarding shares repurchased under the securities repurchase program during the fourth quarter of the year ended December 31, 2010: Period Total Number of Shares (or Units) Purchased (In thousands) Average Price Paid Per Share (or Unit) Total Number of Shares (or Units) Purchased as Approximate Dollar Value of Shares (or Units) that May Part of Publicly Announced Yet Be Purchased under the Plan Plan(1) (In thousands) (In thousands) 10/1/10 - 10/31/10 . . . . . — 11/1/10 - 11/30/10 . . . . . 2,005 shares $52,000 principal amount of 5.375% Convertible Notes 12/1/10 - 12/31/10 . . . . . 300 shares $74,267 principal amount of 5.375% Convertible Notes $ $ $ $ $ — — 25.55 2,005 shares 1.90 per $1.00 $52,000 principal amount of 5.375% principal amount Convertible Notes 29.61 300 shares 2.16 per $1.00 $74,267 principal amount of principal amount 5.375% Convertible Notes $1,500,000 $1,448,755 $1,349,899 $1,341,013 $1,180,620 (1) The purchase of our shares under the normal course issuer bid approved by the board of directors is also subject to a sublimit, as described above. In January 2011, in connection with the securities repurchase program, we repurchased an additional $11.4 million principal amount of the 5.375% Convertible Notes for consideration of $24.8 million. On February 24, 2011, we entered into an agreement to repurchase 7.4 million common shares from ValueAct Capital Master Fund, L.P. (‘‘ValueAct’’) for an aggregate purchase price of $275 million negotiated at a 5.77% discount over a 20-day trading day average, which was calculated in a similar manner to Valeant’s privately negotiated share repurchase from ValueAct completed in May 2010. The transaction, which is subject to closing conditions, is expected to be consummated on March 17, 2011, or such other time or date as the parties to the purchase agreement may agree. G. Mason Morfit is a partner and a member of the Management Committee of ValueAct Capital. Mr. Morfit joined our board of directors on September 28, 2010, effective with the Merger, and prior thereto served as a member of Valeant’s board of directors since 2007. ValueAct Capital is the general partner and the manager of ValueAct. The description set forth above is qualified in its entirety by the purchase agreement, filed herewith as Exhibit 2.10. Item 6. Selected Financial Data The following table of selected consolidated financial data of our Company has been derived from financial statements prepared in accordance with U.S. GAAP. The data is qualified by reference to, and should be read in conjunction with the consolidated financial statements and related notes thereto prepared in accordance with U.S. GAAP (see Item 15 of this Form 10-K) as well as the discussion in Item 7. ‘‘Management’s Discussion and Analysis of Financial Condition and Results of Operations’’. All dollar amounts are expressed in thousands of U.S. dollars, except per share data. Consolidated operating data: Revenue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Operating income (loss) Income (loss) from continuing operations . . . . Net income (loss) . . . . . . . . . . . . . . . . . . . . . Basic and diluted earnings (loss) per share: Year Ended December 31 2010(1) 2009 2008 2007 2006 $1,181,237 (110,085) (208,193) (208,193) $820,430 181,154 176,455 176,455 $757,178 124,109 199,904 199,904 $842,818 188,014 195,539 195,539 $1,067,722 238,867 215,474 211,626 Income (loss) from continuing operations . . . . Net income (loss) . . . . . . . . . . . . . . . . . . . . . Cash dividends declared per share . . . . . . . . . . . $ $ $ (1.06) $ (1.06) $ $ 1.28 1.11 1.11 0.65 $ $ $ 1.25 1.25 1.50 $ $ $ 1.22 1.22 1.50 $ $ $ 1.35 1.32 1.00 28 Consolidated balance sheet: Cash and cash equivalents . . . . . . . . . . . . Working capital . . . . . . . . . . . . . . . . . . . . Total assets . . . . . . . . . . . . . . . . . . . . . . . Long-term obligations . . . . . . . . . . . . . . . Common shares . . . . . . . . . . . . . . . . . . . . Shareholders’ equity (net assets) . . . . . . . . Number of common shares issued and 2010 2009 2008 2007 2006 At December 31 $ 394,269 327,710 10,795,117 3,595,277 5,251,730 4,911,096 $ 114,463 93,734 2,059,290 326,085 1,465,004 1,354,372 $ 317,547 223,198 1,623,565 — 1,463,873 1,201,599 $ 433,641 339,439 1,782,115 — 1,489,807 1,297,819 $ 834,540 647,337 2,192,442 410,525 1,476,930 1,302,257 outstanding (000s) . . . . . . . . . . . . . . . . 302,449 158,311 158,216 161,023 160,444 (1) Amounts for 2010 include the impact of the Merger with Valeant on September 28, 2010, including increased costs as a result of the amortization of intangible assets and inventory step-up and the impact of a restructuring program initiated as a result of the Merger. Item 7. Management’s Discussion and Analysis of Financial Condition and Results of Operations 29 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS INTRODUCTION The following Management’s Discussion and Analysis of Financial Condition and Results of Operations (‘‘MD&A’’) should be read in conjunction with the audited consolidated financial statements, and notes thereto, prepared in accordance with United States (‘‘U.S.’’) generally accepted accounting principles (‘‘GAAP’’) for the fiscal year ended December 31, 2010 (the ‘‘2010 Financial Statements’’). Additional information relating to the Company, including our Annual Report on Form 10-K for the fiscal year ended December 31, 2010 (the ‘‘2010 Form 10-K’’), is available on SEDAR at www.sedar.com and on the U.S. Securities and Exchange Commission (the ‘‘SEC’’) website at www.sec.gov. Unless otherwise indicated herein, the discussion and analysis contained in this MD&A is as of February 28, 2011. All dollar amounts are expressed in U.S. dollars. COMPANY PROFILE On September 28, 2010 (the ‘‘Merger Date’’), Biovail Corporation (‘‘Biovail’’) completed the acquisition of Valeant Pharmaceuticals International (‘‘Valeant’’) through a wholly-owned subsidiary pursuant to an Agreement and Plan of Merger, dated as of June 20, 2010, with Valeant surviving as a wholly-owned subsidiary of Biovail (the ‘‘Merger’’). In connection with the Merger, Biovail was renamed ‘‘Valeant Pharmaceuticals International, Inc.’’ (‘‘we’’, ‘‘us’’, ‘‘our’’ or the ‘‘Company’’). Since the Merger, our strategy is to focus the newly combined Biovail and Valeant businesses on core geographies and therapeutic classes, manage pipeline assets through strategic partnerships with other pharmaceutical companies and deploy cash with an appropriate mix of selective acquisitions, share buybacks and debt repurchases. We believe this strategy will allow us to improve both our growth rates and profitability and to enhance shareholder value, while exploiting the benefits of the Merger. Our leveraged research and development model is one key element to this business strategy. It will allow us to progress development programs to drive future commercial growth, while minimizing our research and development expense. This will be achieved in four ways: • structuring partnerships and collaborations so that our partners share development costs; • bringing products already developed for other markets to new territories; • acquiring dossiers and registrations for branded generic products, which require limited manufacturing start-up and development activities; and • selling internal development capabilities to third parties, thereby allowing higher utilization and infrastructure cost absorption. We will be diverse not only in our sources of revenues from our broad drug portfolio, but also among the therapeutic classes and geographic segments we serve. We will have a focused geographic footprint and focus on those businesses that we view to have the potential for strong operating margins and solid growth, while providing natural balance across geographies. In addition, we will have an established portfolio of specialty pharmaceutical, branded generic and over-the-counter (‘‘OTC’’) products with a focus in the dermatology therapeutic area. We will measure our success through shareholder returns and, on that basis, as of February 23, 2011, the market price of our common shares on the New York Stock Exchange (‘‘NYSE’’) has increased approximately 50% since the Merger Date. 30 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) BIOVAIL MERGER WITH VALEANT Description of the Transaction On September 28, 2010, a wholly-owned subsidiary of Biovail acquired all of the outstanding equity of Valeant in a share transaction, in which each share of Valeant common stock was cancelled and converted into the right to receive 1.7809 Biovail common shares. The share consideration was valued at $26.35 per share based on the market price of Biovail’s common shares as of the Merger Date. In addition, immediately preceding the effective time of the Merger, Valeant paid its stockholders a special dividend of $16.77 per share (the ‘‘pre-Merger special dividend’’) of Valeant common stock. As a result of the Merger, Valeant became a wholly-owned subsidiary of Biovail. On December 22, 2010, the Company paid a post-Merger special dividend of $1.00 per common share (the ‘‘post-Merger special dividend’’). The post-Merger special dividend comprised aggregate cash paid of $297.6 million and 72,283 shares issued to shareholders that elected to reinvest in additional common shares of the Company through a special dividend reinvestment plan, which plan was terminated following payment of the post-Merger special dividend. Valeant is a multinational specialty pharmaceutical company that develops, manufactures and markets a broad range of pharmaceutical products. Valeant’s specialty pharmaceutical and OTC products are marketed under brand names and are sold in the U.S., Canada, Australia and New Zealand, where Valeant focuses most of its efforts on the dermatology and neurology therapeutic classes. Valeant also has branded generic and OTC operations in Europe and Latin America, which focus on pharmaceutical products that are bioequivalent to original products and are marketed under company brand names. The Merger has resulted in, and is expected to continue to result in, significant strategic benefits to the Company through the creation of a larger, more globally diversified company with a broader and better diversified array of products and an expanded presence in North America and internationally. In addition, the market capitalization, profitability and free cash flow of the Company are, and are expected to continue to be, stronger relative to either Biovail or Valeant on a stand-alone basis. We have achieved, and expect to continue to achieve, significant operational cost savings, coming from, among other things, reductions in research and development, general and administrative expenses, and sales and marketing. Basis of Presentation The transaction has been accounted for as a business combination under the acquisition method of accounting, which requires, among other things, the share consideration transferred be measured at the acquisition date based on the then-current market price and that most assets acquired and liabilities assumed be recognized at their fair values as of the acquisition date. Biovail was both the legal and accounting acquirer in the Merger. Accordingly, the Company’s consolidated financial statements reflect the assets, liabilities and results of operations of Valeant from the Merger Date. Acquisition-related transaction costs and certain acquisition-related restructuring charges are not included as a component of the acquisition accounting, but are accounted for as expenses in the periods in which the costs are incurred. 31 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Fair Value of Consideration Transferred ($ in 000s, except per share data; Number of shares, stock options and restricted share units in thousands) Conversion Calculation Fair Value Form of Consideration Number of common shares of Biovail issued in exchange for Valeant common stock outstanding as of the Merger Date . . . . . . . . . . . . . . . . . . . . . . . . . Multiplied by Biovail’s stock price as of the Merger Date(a) . . . . . . . . . . . . . . 139,137 26.35 $ Number of common shares of Biovail expected to be issued pursuant to vested Valeant restricted share units (‘‘RSUs’’) as a result of the Merger . . . . . . . . . . . . . . . . . . . . . . Multiplied by Biovail’s stock price as of the Merger date(a) 1,694 26.35 $ $3,666,245 Common shares 44,643 Common shares Fair value of vested and partially vested Valeant stock options converted into Biovail stock options . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110,687 Stock options Fair value of vested and partially vested Valeant RSUs converted into Biovail RSUs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cash consideration paid and payable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58,726 RSUs 51,739 Cash(b) Total fair value of consideration transferred . . . . . . . . . . . . . . . . . . . . . . . . $3,932,040 (a) As the Merger was effective at 12:01 a.m. on September 28, 2010, the conversion calculation reflects the closing price of Biovail’s common shares on the NYSE at September 27, 2010. (b) Cash consideration includes $39.7 million of income tax withholdings paid by the Company on behalf of employees of Valeant, in connection with the net share settlement of certain vested Valeant RSUs as of the Merger Date. In addition, under the terms of the Company’s employment agreement with J. Michael Pearson, Chief Executive Officer, cash equal to the pre-Merger special dividend payment will be paid to Mr. Pearson in respect of any of his 2008 performance awards that vest in February 2011 at the time of such vesting. As of the Merger Date, the aggregate amount of this cash payment in respect of the pre-Merger special dividend was estimated to be $13.7 million based on the assumption that Mr. Pearson’s 2008 performance awards will vest at the maximum performance target. Of that amount, the portion attributable to Mr. Pearson’s pre-Merger service ($12.1 million) was recognized in the fair value of consideration transferred, while the portion attributable to Mr. Pearson’s post-Merger service ($1.6 million) is being recognized as share-based compensation expense over the remaining vesting period from the Merger Date to February 2011. Assets Acquired and Liabilities Assumed The following table summarizes the estimated fair values of the assets acquired and liabilities assumed as of the Merger Date. The following recognized amounts are provisional and subject to change: • the amounts and useful lives for identifiable intangible assets, pending the finalization of valuation efforts; • the amounts for income tax assets and liabilities, pending finalization of estimates and assumptions in respect of certain tax aspects of the transaction, and the filing of Valeant’s pre-Merger tax returns; and • the allocation of goodwill among reporting units, pending the completion of the allocation of the consideration transferred to the assets acquired and liabilities assumed. The Company will finalize these amounts as it obtains the information necessary to complete the measurement process. Any changes resulting from facts and circumstances that existed as of the Merger Date may result in retrospective adjustments to the provisional amounts recognized at the Merger Date. These 32 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) changes could be significant. The Company expects to finalize these amounts no later than one year from the Merger Date. ($ in 000s) Cash and cash equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . Accounts receivable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Inventories(c) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other current assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Property, plant and equipment . . . . . . . . . . . . . . . . . . . . . . Identifiable intangible assets, excluding in-process research and development(d) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . In-process research and development(e) . . . . . . . . . . . . . . . . Other non-current assets . . . . . . . . . . . . . . . . . . . . . . . . . . . Current liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Long-term debt, including current portion(f) . . . . . . . . . . . . . Deferred income taxes, net . . . . . . . . . . . . . . . . . . . . . . . . . Other non-current liabilities . . . . . . . . . . . . . . . . . . . . . . . . Total indentifiable net assets . . . . . . . . . . . . . . . . . . . . . . . . Equity component of 4.0% Convertible Notes(f) . . . . . . . . . . Call option agreements . . . . . . . . . . . . . . . . . . . . . . . . . . . . Goodwill(g) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Amounts Recognized as of Merger Date (as previously reported)(a) $ 348,637 194,930 208,874 33,460 184,757 3,844,310 1,399,956 5,905 (384,223) (2,913,614) (1,472,321) (140,397) 1,310,274 (225,971) (28,000) 2,863,653 Total fair value of consideration transferred . . . . . . . . . . . . . 3,919,956 Measurement Period Adjustments(b) $ — — — (2,591) — — 5,000 203 (1,351) — 4,530 (8,910) (3,119) — — 15,203 12,084 Amounts Recognized as of Merger Date (as adjusted) $ 348,637 194,930 208,874 30,869 184,757 3,844,310 1,404,956 6,108 (385,574) (2,913,614) (1,467,791) (149,307) 1,307,155 (225,971) (28,000) 2,878,856 3,932,040 (a) As previously reported in the Company’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2010. (b) The measurement period adjustments primarily reflect: (i) an increase in the total fair value of consideration transferred to recognize the estimated cash payment in respect of the pre-Merger special dividend on Mr. Pearson’s 2008 performance awards (as described above under ‘‘Fair Value of Consideration Transferred’’); (ii) a change in the fair value of acquired in-process research and development (‘‘IPR&D’’) assets related to the value ascribed to taribarivin (as described below under ‘‘Acquisitions — Ribavirin’’); and (iii) the tax impact of pre-tax measurement period adjustments. The measurement period adjustments were made to reflect facts and circumstances existing as of the Merger Date, and did not result from intervening events subsequent to the Merger Date. These adjustments did not have a significant impact on the Company’s previously reported consolidated financial statements for the quarter ended September 30, 2010 and, therefore, the Company has not retrospectively adjusted those financial statements. (c) Includes $72.1 million to record Valeant’s inventory at its estimated fair value, which is being recognized as a charge to cost of goods sold as the inventory acquired is subsequently sold, including $53.3 million in the fourth quarter of 2010. The remaining inventory acquisition accounting adjustment of $18.8 million is expected to be substantially included in cost of goods sold in the first quarter of 2011. 33 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) (d) The following table summarizes the provisional amounts and useful lives assigned to identifiable intangible assets: ($ in 000s) Product brands . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Corporate brands . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Product rights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Out-licensed technology and other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Total identifiable intangible assets acquired . . . . . . . . . . . . . . . . . . . . . . . . Weighted- Average Useful Lives Amounts Recognized as of Merger Date (Years) 16 20 9 7 15 $ 3,114,689 168,602 360,970 200,049 3,844,310 (e) Acquired IPR&D assets are initially recognized at fair value and are classified as indefinite-lived intangible assets until the successful completion or abandonment of the associated research and development efforts. the development of The significant components of ezogabine/retigabine in collaboration with Glaxo Group Limited, a subsidiary of GlaxoSmithKline plc (the entities within The Glaxo Group of Companies are referred throughout as ‘‘GSK’’), and a number of dermatology products, which are described below under ‘‘Products in Development’’. The following table summarizes the provisional amounts assigned to acquired IPR&D assets: the acquired IPR&D assets relate to ($ in 000s) Ezogabine/retigabine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Dermatology products . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Amounts Recognized as of Merger Date $ 891,461 431,323 82,172 Total IPR&D assets acquired . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,404,956 A multi-period excess earnings methodology (income approach) was used to determine the estimated fair values of the acquired IPR&D assets. The projected cash flows from these assets were adjusted for the probabilities of successful development and commercialization of each project. A risk-adjusted discount rate of 9% was used to present value the projected cash flows. Material cash inflows are expected to commence in 2011 for ezogabine/retigabine and between 2013 and 2016 for the dermatology products. Solely for purposes of estimating the fair value of these assets, we have estimated that we will incur costs of approximately $200 million to complete the products in development. The efforts required to develop the IPR&D assets into commercially viable products include completion of the pre-clinical development, clinical-trial testing, regulatory approval, and commercialization. The principal risks relating to these assets include the outcomes of the formulation development, clinical studies, and regulatory filings. Since pharmaceutical products cannot be marketed without regulatory approvals, we will not receive any benefits unless regulatory approval is obtained. As a result, there is no certainty that any of our development efforts related to these assets will result in commercially viable products. (f) In connection with the Merger, Valeant secured financing of $125.0 million under a senior secured revolving credit facility (the ‘‘Revolving Credit Facility’’), $1.0 billion under a senior secured term loan A facility (the ‘‘Term Loan A Facility’’), and $1.625 billion under a senior secured term loan B facility (the ‘‘Term Loan B Facility’’ and, together with the Revolving Credit Facility and Term Loan A Facility, the ‘‘Credit 34 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Facilities’’), and used a portion of the proceeds to undertake the following transactions prior to the Merger Date: • fund the payment of the pre-Merger special dividend; • fund the legal defeasance of Valeant’s existing 8.375% and 7.625% senior unsecured notes, by depositing with the trustees amounts sufficient to pay 100% of the outstanding aggregate principal amount of the notes, plus applicable premium and accrued and unpaid interest, on October 27, 2010; and • fund the repayment in full of indebtedness under Valeant’s existing senior secured term loan. Concurrent with the closing of the Merger, Valeant issued $500.0 million aggregate principal amount of 6.75% senior notes due 2017 (the ‘‘2017 Notes’’) and $700.0 million aggregate principal amount of 7.00% senior notes due 2020 (the ‘‘2020 Notes’’). A portion of the proceeds of the 2017 Notes and 2020 Notes offering was used to pay down $1.0 billion of the Term Loan B Facility. Valeant incurred $118.4 million of debt issuance costs in connection with the above financings that were ascribed a fair value of nil in the acquisition accounting. In addition, as of the Merger Date, Valeant had $225.0 million outstanding principal amount of 4.0% convertible subordinated notes due 2013 (the ‘‘4.0% Convertible Notes’’). The Company is required to separately account for the liability component and equity component of the 4.0% Convertible Notes, as these notes have cash settlement features. The fair value of the 4.0% Convertible Notes was determined to be $446.5 million. A fair value of $220.5 million has been allocated to the liability component in a manner reflecting the Company’s interest rate for a similar debt instrument without a conversion feature. The residual of the fair value of $226.0 million represents the carrying amount of the equity component, which was recorded as additional paid-in capital in the Company’s consolidated shareholders’ equity. The following table summarizes the fair value of long-term debt assumed as of the Merger Date: ($ in 000s) Term Loan A Facility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Term Loan B Facility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2017 Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2020 Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4.0% Convertible Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 1,000,000 500,000 497,500 695,625 220,489 Total long-term debt assumed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2,913,614 (g) Goodwill is calculated as the difference between the Merger Date fair value of the consideration transferred and the provisional values assigned to the assets acquired and liabilities assumed. None of the goodwill is expected to be deductible for tax purposes. The goodwill recorded represents the following: • cost savings, operating synergies and other benefits expected to result from combining the operations of Valeant with those of Biovail; • the value of the going-concern element of Valeant’s existing business (that is, the higher rate of return on the assembled net assets versus if Biovail had acquired all of the net assets separately); and • intangible assets that do not qualify for separate recognition (for instance, Valeant’s assembled workforce), as well as future, as yet unidentified research and development projects. Acquisition-Related Costs We have incurred to date $38.3 million of transaction costs directly related to the Merger, which includes expenditures for advisory, legal, valuation, accounting and other similar services. These costs have been expensed as acquisition-related costs. 35 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) ACQUISITIONS Cholestagel(cid:4) On February 9, 2011, we acquired the Canadian rights to Cholestagel(cid:4), an oral bile acid sequestrant for hypercholesterolemia, from Genzyme Corporation for a $2.0 million upfront payment, to be followed by potential additional milestone payments totaling up to $7.0 million. ACZONE(cid:4) On February 7, 2011, we entered into an agreement to license the Canadian rights to ACZONE(cid:4) Gel 5%, a topical formulation of dapsone used in the treatment of acne vulgaris, from Allergan, Inc. for an upfront payment of approximately $0.5 million and subsequent additional payments based on net sales. Zovirax(cid:4) On February 2, 2011, we entered into an asset purchase agreement to acquire U.S. rights to non-ophthalmic topical formulations of Zovirax(cid:4) from GSK. Following receipt of Hart-Scott-Rodino regulatory clearance, we closed the U.S. transaction on February 22, 2011. In addition, concurrent with the execution of the U.S. agreement, we entered into a binding letter of intent with GSK to acquire the Canadian rights to non-ophthalmic topical formulations of Zovirax(cid:4) and we are in the process of negotiating a definitive agreement for such acquisition. Pursuant to the terms of the asset purchase agreement, we paid to GSK an aggregate amount of $300.0 million in cash for both the U.S. and Canadian rights upon the closing of the U.S. transaction. No additional payments will be made to GSK upon the closing of the Canadian transaction. We have been marketing Zovirax(cid:4) in the U.S. since January 1, 2002, under a 20-year exclusive distribution agreement with GSK, which distribution agreement terminated following the closing of the U.S. transaction. We have entered into a new supply agreement and a new trademark and domain name license agreement with GSK with respect to the U.S. territory. PharmaSwiss On January 31, 2011, we entered into a stock purchase agreement to purchase all of the issued and outstanding stock of PharmaSwiss S.A. (‘‘PharmaSwiss’’), a privately-owned branded generics and OTC pharmaceutical company based in Zug, Switzerland. The aggregate consideration payable is A350.0 million (approximately $479.0 million as of January 31, 2011) plus up to an additional A30.0 million (approximately $41.0 million as of January 31, 2011) in contingent payments if certain net sales milestones of PharmaSwiss are achieved for the calendar year ended 2011. The closing consideration is also subject to a working capital adjustment. PharmaSwiss is an existing partner to several large pharmaceutical and biotech companies offering regional expertise in such functions as regulatory, compliance, sales, marketing and distribution, in addition to developing its own product portfolio. Through its business operations, PharmaSwiss offers a broad product portfolio in seven therapeutic areas and operations in 19 countries throughout Central and Eastern Europe, including Poland, Hungary, the Czech Republic and Serbia, as well as in Greece and Israel. The transaction, which is subject to customary closing conditions, including certain regulatory approvals, is expected to close in the first quarter of 2011. Ribavirin On November 1, 2010, we paid Kadmon Pharmaceuticals LLC (‘‘Kadmon’’) $7.5 million for exclusive rights to certain dosage forms of ribavirin in Poland, Hungary, the Czech Republic, Slovakia, Romania and Bulgaria. Ribavirin is indicated for the treatment of viral diseases, including hepatitis C virus. The total purchase price has been capitalized as a product right intangible asset with an estimated useful life of 10 years. 36 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Under a separate agreement dated November 1, 2010, the Company granted Kadmon an exclusive, worldwide license to taribavirin, excluding the territory of Japan, in exchange for an upfront payment of $5.0 million, other development milestones, and royalty payments in the range of 8-12% of future net sales. The fair value associated with taribavirin was included in the acquired IPR&D assets identified as of the Merger Date. Hamilton Brands On October 29, 2010, we acquired the intellectual property, trademarks and inventory related to the Hamilton skin care brand in Australia for cash consideration of $14.7 million. The purchase price was allocated to the trademark intangible asset ($11.7 million) and inventory ($3.0 million). The useful life of the trademark intangible asset was estimated to be 10 years. Istradefylline On June 2, 2010, we entered into a license agreement with Kyowa Hakko Kirin Co., Ltd. (‘‘Kyowa Hakko Kirin’’) to acquire the U.S. and Canadian rights to develop and commercialize products containing istradefylline — a new chemical entity targeted for the treatment of Parkinson’s disease. Under the terms of the license agreement, we paid an upfront fee of $10.0 million, and we could pay up to $20.0 million in potential development milestones through U.S. Food and Drug Administration (‘‘FDA’’) approval and up to an additional $35.0 million if certain sales-based milestones are met. We will also make tiered royalty payments of up to 30% on net commercial sales of products containing istradefylline. In connection with this acquisition, we also entered into an agreement with Kyowa Hakko Kirin for the supply of the istradefylline compound. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, the $10.0 million upfront payment, together with $0.2 million of acquisition costs, was charged to acquired IPR&D expense in the second quarter of 2010. AMPAKINE(cid:4) On March 25, 2010, we acquired certain AMPAKINE(cid:4) compounds, including associated intellectual property, from Cortex Pharmaceuticals, Inc. (‘‘Cortex’’) for use in the field of respiratory depression, a brain- mediated breathing disorder. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, upfront payments totaling $10.0 million made by us to Cortex, together with $0.7 million of acquisition costs, were charged to acquired IPR&D expense in the first quarter of 2010. As described below under ‘‘Restructuring and Integration — Merger-Related Cost-Rationalization and Integration Initiatives — Research and Development Pipeline Rationalization’’, we have suspended development of the AMPAKINE(cid:4) compounds and are reviewing our options with Cortex. Staccato(cid:4) Loxapine On February 9, 2010, we entered license agreement with Alexza Pharmaceuticals, Inc. (‘‘Alexza’’) to acquire the U.S. and Canadian development and commercialization rights to Staccato(cid:4) loxapine (AZ-004) for the treatment of psychiatric and/or neurological indications and the symptoms associated with these indications. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, the $40.0 million upfront payment made by us to Alexza, together with $0.3 million of acquisition costs, was charged to acquired IPR&D expense in the first quarter of 2010. into a collaboration and As described below under ‘‘Restructuring and Integration — Merger-Related Cost-Rationalization and Integration Initiatives — Research and Development Pipeline Rationalization’’, we have terminated the collaboration and license agreement with Alexza. 37 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) PRODUCTS IN DEVELOPMENT We currently have the following products, among others, in clinical development: • Ezogabine/Retigabine As described below under ‘‘Collaboration Agreement’’, together with GSK, we are developing a compound as an adjunctive treatment for partial-onset seizures in patients with epilepsy whose generic name will be ezogabine in the U.S. and retigabine in all other countries. Ezogabine/retigabine stabilizes hyper-excited neurons primarily by opening neuronal potassium channels. On October 30, 2009, a New Drug Application (‘‘NDA’’) was filed for ezogabine for the treatment of refractory partial-onset seizures and the FDA accepted the NDA for review on December 29, 2009. On August 30, 2010, the FDA extended the Prescription Drug User Fee Act goal date for ezogabine to November 30, 2010 due to the recent submission of a solicited formal Risk Evaluation and Mitigation Strategy (‘‘REMS’’). The REMS was requested by the FDA in correspondence dated August 16, 2010, and was submitted to the FDA on August 26, 2010. On November 30, 2010, we received a Complete Response Letter from the FDA for ezogabine. We are evaluating the Complete Response Letter in which the FDA cited non-clinical reasons for this action and we believe that these items can be addressed and are working for a timely response to the FDA as soon as possible in 2011. Also, the European Medicines Evaluation Agency confirmed on November 17, 2009 that the Marketing Authorization Application (‘‘MAA’’) filed on October 30, 2009 for ezogabine/retigabine was successfully validated, thus enabling the MAA review to commence. In January 2011, the European Medicines Agency’s Committee for Medicinal Products for Human Use issued an opinion recommending marketing authorization for Trobalt(cid:5) (retigabine) as an adjunctive (add-on) treatment of partial-onset seizures, with or without secondary generalization in adults aged 18 years and above with epilepsy. Additionally, retigabine received a preliminary approval from the Swiss Agency for Therapeutic Products, Swissmedic, in December 2010. • Istradefylline (as described above under ‘‘Acquisitions — Istradefylline’’). • Dermatology Products A number of dermatology product candidates are in development including: • IDP-107 is an oral treatment for moderate to severe acne vulgaris. Acne is a disorder of the pilosebaceous unit characterized by (pimples) and non-inflammatory (whiteheads and blackheads) lesions, predominately on the face. Acne vulgaris is a common skin disorder that affects about 85% of people at some point in their lives. We are currently enrolling patients in a Phase 2b clinical trial to evaluate the safety and efficacy of IDP-107. the presence of inflammatory • IDP-108, a novel triazole compound, is an antifungal targeted to treat onychomycosis, a fungal infection of the fingernails and toenails primarily in older adults. The mechanism of antifungal activity appears similar to other antifungal triazoles, i.e., ergosterol synthesis inhibition. IDP-108 is a non-lacquer formulation designed for topical delivery into the nail. We are currently conducting a Phase 3 clinical trial to evaluate the safety and efficacy of IDP-108. • IDP-109 is a compound targeted for treatment of common warts. There is no currently approved prescription treatment for common warts. Common warts is an infection caused by a viral infection (human papilloma virus) and occurs most frequently on the hands. This product is currently in Phase 1 stage of development. • IDP-115 combines an established anti-rosacea active ingredient with sunscreen agents to provide sun protection in the same topical treatment for rosacea patients. Rosacea is a common condition treated by dermatologists and characterized by multiple signs and symptoms including papules, 38 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) pustules and erythema, most commonly on the central area of the face. This product has completed Phase 2 clinical trials • IDP-118 is a topical product targeted to treat psoriasis. Psoriasis is a chronic, autoimmune disease that appears on the skin. This product is currently in Phase 1 stage of development. • Lifecycle Management Projects Through Valeant’s acquisition of Aton, we have ongoing lifecycle management programs in place for several of our specialty central nervous system (‘‘CNS’’) compounds, including Syprine(cid:4) and Mephyton(cid:4), as well as Lacrisert(cid:4), which is in our dermatology portfolio. We are developing improvements to these compounds in order to better meet the needs expressed by the medical community. COLLABORATION AGREEMENT In October 2008, Valeant closed the worldwide License and Collaboration Agreement (the ‘‘Collaboration Agreement’’) with GSK, to develop and commercialize ezogabine/retigabine. Pursuant to the terms of the Collaboration Agreement, Valeant granted co-development rights and worldwide commercialization rights to GSK. Valeant agreed to share equally with GSK the development and pre-commercialization expenses of ezogabine/retigabine in the U.S., Australia, New Zealand, Canada and Puerto Rico (the ‘‘Collaboration Territory’’). Following the launch of an ezogabine/retigabine product, we will share equally in the profits of ezogabine/retigabine in the Collaboration Territory. In addition, Valeant granted GSK an exclusive license to develop and commercialize retigabine in countries outside of the Collaboration Territory and certain backup compounds to ezogabine/retigabine worldwide. GSK is responsible for all expenses outside of the Collaboration Territory and will solely fund the development of any backup compound. We will receive up to a 20% royalty on net sales of retigabine outside of the Collaboration Territory. In addition, if backup compounds are developed and commercialized by GSK, GSK will pay us royalties of up to 20% of net sales of products based upon such backup compounds. GSK has the right to terminate the Collaboration Agreement at any time prior to the receipt of the approval by the FDA of an NDA for an ezogabine product, which right may be irrevocably waived at any time by GSK. Unless otherwise terminated, the Collaboration Agreement will continue on a country-by-country basis until GSK has no remaining payment obligations with respect to such country. Under the terms of the Collaboration Agreement, GSK will pay us up to $545.0 million based upon the achievement of certain regulatory, commercialization and sales milestones, and the development of additional indications for ezogabine/retigabine. GSK will also pay us up to an additional $150.0 million if certain regulatory and commercialization milestones are achieved for backup compounds to ezogabine/retigabine. Our rights to ezogabine/retigabine are subject to an asset purchase agreement between Meda Pharma GmbH & Co. KG (‘‘Meda Pharma’’) and Xcel Pharmaceuticals, Inc., which was acquired by Valeant in 2005 (the ‘‘Meda Pharma Agreement’’). Under the Meda Pharma Agreement, we may be required to make certain milestone and royalty payments to Meda Pharma. Within the Collaboration Territory, any royalties to Meda Pharma will be shared by us and GSK. In the rest of the world, we will be responsible for the payment of these royalties to Meda Pharma from the royalty payments we receive from GSK. Our interest in ezogabine/retigabine was recorded at a provisional fair value of $891.5 million as of the Merger Date (as described above under ‘‘Biovail Merger with Valeant — Assets Acquired and Liabilities Assumed’’). 39 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) RESTRUCTURING AND INTEGRATION Merger-Related Cost-Rationalization and Integration Initiatives We believe the complementary nature of the Biovail and Valeant businesses presents an opportunity to capture significant operating synergies and cost savings. The Merger has provided, and should continue to provide, opportunities to realize cost savings from, among other things, reductions in research and development, general and administrative expenses, and sales and marketing. In total, we have identified over $310 million of annual cost synergies that we expect to realize by the end of 2012, $270 million of which will be realized in 2011. Over $50 million of cost synergies were realized in the fourth quarter of 2010. This amount does not include potential revenue synergies or the potential benefits of expanding the Biovail corporate structure to Valeant’s operations. Further, we currently expect our combined cash tax rate to be less than 10% for 2011. We have initiated cost-rationalization and integration initiatives to capture operating synergies and generate cost savings across the Company. These measures include: • workforce reductions across the Company and other organizational changes; • closing of duplicative facilities and other site rationalization actions company-wide, including research and development facilities, sales offices and corporate facilities; • leveraging research and development spend; • increased use of shared services; and • procurement savings. We estimate that we will incur costs in the range of $135 million and $180 million (of which the non-cash component, including share-based compensation, is expected to be approximately $55 million) in connection with these cost-rationalization and integration initiatives. These costs include employee termination costs (including related share-based payments), costs to consolidate or close facilities and relocate employees, asset impairments, and contract termination and lease cancellation costs. The following costs were incurred in connection with these initiatives through December 31, 2010: ($ in 000s) Employee Termination Costs Severance and Related Benefits Share-Based Compensation $ $ Costs incurred and charged to expense . Cash payments . . . . . . . . . . . . . . . . . . . Non-cash adjustments . . . . . . . . . . . . . . 58,727 (33,938) — 49,482 — (49,482) Balance, December 31, 2010 . . . . . . . . . 24,789 — IPR&D Termination Costs(1) $ 13,750 (13,750) — — Contract Termination, Facility Closure and Other Costs $ 12,862 (8,755) (2,437) 1,670 Total $ 134,821 (56,443) (51,919) 26,459 (1) As described below under ‘‘— Research and Development Pipeline Rationalization’’. We do not record restructuring costs in the Company’s business segments. Employee Termination Costs We recognized employee termination costs of $58.7 million for severance and related benefits payable to approximately 500 employees of Biovail and Valeant who have been, or will be, terminated as a result of the Merger. These reductions primarily reflect the elimination of redundancies and consolidation of staff in the research and development, general and administrative and sales and marketing functions. As of December 31, 2010, $33.9 million of the termination costs had been paid, and we expect that a significant portion of the remaining costs will be paid prior to April 1, 2011, with the balance payable through to the first quarter of 2012. 40 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) In addition, we recognized incremental share-based compensation expense of $49.5 million, related to the following stock options and RSUs held by terminated employees of Biovail and Valeant: ($ in 000s) Stock options and time-based RSUs held by Biovail employees with employment agreements . . . . . . Stock options held by Biovail employees without employment agreements . . . . . . . . . . . . . . . . . . . . Performance-based RSUs held by Biovail executive officers and selected employees . . . . . . . . . . . . Stock options and RSUs held by former executive officers of Valeant . . . . . . . . . . . . . . . . . . . . . . . $ 9,622 (492) 20,287 20,065 49,482 Research and Development Pipeline Rationalization Prior to the Merger, our product development and business development efforts were focused on unmet medical needs in specialty CNS disorders. Since the Merger, we have been employing a leveraged research and development model that allows us to progress development programs, while minimizing research and development expense, through partnerships and other means. In consideration of this model, following the Merger, we conducted a strategic and financial review of our product development pipeline and identified the programs that did not align with the Company’s new research and development model. These programs are outlined in the table below. In respect of the Staccato(cid:4) loxapine, GDNF, tetrabenazine, fipamezole and pimavanserin programs, we provided notices of termination to, or entered into termination agreements with, the counterparties to the agreements. Regarding the AMPAKINE(cid:4) program, we have suspended development of these compounds and are reviewing our options with Cortex. ($ in 000s) Programs AZ-004 BVF-007 BVF-014 BVF-018 BVF-025 BVF-036, -040,-048 Counterparty Compound Alexza Cortex MedGenesis Therapeutix Inc. LifeHealth Limited Santhera Pharmaceuticals (Switzerland) Ltd. Staccato(cid:4) loxapine . . . . . . . . AMPAKINE(cid:4) . . . . . . . . . . . . GDNF . . . . . . . . . . . . . . . . . Tetrabenazine . . . . . . . . . . . . ACADIA Pharmaceuticals Inc. Pimavanserin . . . . . . . . . . . . $365,000 $ 8,750(2) Fipamezole . . . . . . . . . . . . . $200,000 Nil Contingent Milestone Obligations Terminated(1) $ 90,000 $ 15,000 $ 20,000 Nil IPR&D Termination Charges Nil Nil $ 5,000(2) $28,000(3) (1) Represents the maximum amount of previously disclosed milestone payments we could have been required to make to the counterparty under each agreement. These milestone payments were contingent on the achievement of specific developmental, regulatory and commercial milestones. In addition, we could have been obligated to make royalty payments based on future net sales of the products if regulatory approval was obtained. As a consequence of the termination of these arrangements, we have no ongoing or future obligation in respect of these milestone or royalty payments. (2) Represents the amount of negotiated settlements with each counterparty that we recognized and paid in the fourth quarter of 2010. (3) Represents the carrying amount of the related acquired IPR&D asset capitalized in connection with the acquisition of the worldwide development and commercialization rights to tetrabenazine in June 2009. In addition to the settlement payments identified in the table above, we have incurred internal and external costs of $5.3 million in the fourth quarter of 2010 that were directly associated with the fulfillment of our remaining contractual obligations under these terminated arrangements, which costs have been recognized as restructuring costs. Following the completion of these activities, we intend to vacate our remaining research and development facility in Chantilly, Virginia, and, as a result, we recognized $3.0 million of accelerated 41 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) depreciation arising from the reduced useful life of the equipment and leasehold improvements located at this facility. Pre-Merger Cost Rationalization Initiatives In May 2008, we initiated restructuring measures that were intended to rationalize our manufacturing operations, pharmaceutical sciences operations, and general and administrative expenses. The following costs were incurred in connection with these initiatives through December 31, 2010: Asset Impairments Employee Termination Costs Manufacturing Pharmaceutical Sciences Corporate Manufacturing Pharmaceutical Sciences Contract Termination, Facility Closure and Other Costs ($ in 000s) Balance, January 1, 2008 . . Costs incurred and charged to expense . . . . . . . . . . Cash payments . . . . . . . . . Non-cash adjustments . . . . $ — 42,602 — (42,602) Balance, December 31, 2008 — Costs incurred and charged to expense . . . . . . . . . . Cash payments . . . . . . . . . Non-cash adjustments . . . . 7,591 — (7,591) Balance, December 31, 2009 — Costs incurred and charged to expense . . . . . . . . . . Cash payments . . . . . . . . . Non-cash adjustments . . . . Balance, December 31, 2010 400 — (400) — Manufacturing Operations $ — 16,702 — (16,702) — 2,784 — (2,784) — — — — — $ — — — — — 10,968 — (10,968) — — — — — $ — 3,309 — — 3,309 4,942 (2,041) — 6,210 1,330 (7,540) — — $ — 2,724 (2,724) — — 1,441 (1,278) 71 234 1,924 (2,057) (101) — $ — 4,865 (333) (1,186) 3,346 2,307 (1,321) — 4,332 2,365 (3,017) — 3,680 Total $ — 70,202 (3,057) (60,490) 6,655 30,033 (4,640) (21,272) 10,776 6,019 (12,614) (501) 3,680 On January 15, 2010, we completed the sale of our Dorado, Puerto Rico manufacturing facility for net cash proceeds of $8.5 million. The related property, plant and equipment was classified as assets held for sale on the consolidated balance sheet as of December 31, 2009. We occupied the Dorado facility until March 31, 2010, pursuant to a short-term lease agreement with the buyer. As of September 30, 2010, we completed the transfer of remaining manufacturing processes from our Carolina, Puerto Rico manufacturing facility to our plant in Steinbach, Manitoba. Following the end of production, we incurred internal and external costs of $1.3 million directly associated with the final shutdown of the Carolina facility, which costs have been recognized as restructuring costs. We also recorded an impairment charge of $0.4 million to write off the remaining carrying value of the Carolina facility after unsuccessful efforts to locate a buyer for the facility. We incurred employee termination costs of $9.6 million in total for severance and related benefits payable to the approximately 240 employees terminated as a result of the closure of the Dorado and Carolina facilities. As these employees were required to provide service during the shutdown period in order to be eligible for termination benefits, we were recognizing the cost of those termination benefits ratably over the estimated future service period. In 2009 and 2008, we recorded impairment charges of $7.6 million and $42.6 million, respectively, to write down the carrying value of the property, plant and equipment located in Puerto Rico to its estimated fair value. 42 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Pharmaceutical Sciences Operations On July 23, 2010, we completed the sale of our contract research division (‘‘CRD’’) to Lambda Therapeutic Research Inc. (‘‘Lambda’’) for net cash proceeds of $6.4 million. We no longer considered CRD a strategic fit as a result of our pre-Merger transition from reformulation programs to the in-licensing, acquisition and development of specialty CNS products. CRD has not been treated as a discontinued operation for accounting purposes, on the basis that its operations were immaterial and incidental to our core business. The net assets of CRD at the date of disposal comprised net current assets and liabilities of $1.6 million and property, plant and equipment of $4.8 million. We recognized employee termination costs of $1.9 million for the approximately 70 CRD employees not offered employment by Lambda. The consolidated statements of income (loss) for 2010, 2009 and 2008 included the following revenue and expenses of CRD, which, as described above, have not been segregated from continuing operations: ($ in 000s) 2010 $ 2009 $ 2008 $ Service and other revenues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5,642 12,027 21,191 Cost of services . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Selling, general and administrative expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7,211 2,328 13,849 3,718 23,033 4,150 Total operating expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9,539 17,567 27,183 Operating loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Foreign exchange gain (loss) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (3,897) (102) (5,540) 93 (5,992) 931 Net loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (3,999) (5,447) (5,061) Prior to 2010, we completed the closure of our research and development facilities in Mississauga, Ontario and Dublin, Ireland, and the consolidation of our research and development operations in Chantilly, Virginia. Corporate Headquarters In November 2009, we completed the sale and leaseback of our corporate headquarters in Mississauga, Ontario for net proceeds of $17.8 million. We recognized a loss on disposal of $11.0 million. We have continued to occupy this facility under a 20-year operating lease at market rental rates. Minimum future rental payments under this lease are approximately $43.1 million. Our intention is to vacate this facility in the first half of 2011 and relocate to a smaller leased facility. Results of Pre-Merger Cost Rationalization Initiatives Our pre-Merger cost rationalization initiatives were substantively implemented prior to the Merger. In the aggregate, these initiatives resulted in cumulative charges to earnings of $105.6 million, of which the cash component amounted to $32.3 million. With the sale of CRD, we realized our target of $70 million in total gross proceeds from the divestiture and monetization of non-core assets. U.S. HEALTHCARE REFORM In March 2010, the Patient Protection and Affordable Care Act was enacted in the U.S. This healthcare reform legislation contains several provisions that impact our business. Provisions of the new legislation include: (i) an increase in the minimum Medicaid rebate to states participating in the Medicaid program from 15.1% to 23.1% on covered drugs; (ii) the extension of the Medicaid rebate to Managed Care Organizations that dispense drugs to Medicaid beneficiaries; and (iii) the expansion of the 340(B) Public Health Services drug pricing 43 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) program, which provides outpatient drugs at reduced rates, to include additional hospitals, clinics, and healthcare centres. Commencing in 2011, the new legislation requires that drug manufacturers provide a 50% discount to Medicare beneficiaries whose prescription drug costs cause them to be subject to the Medicare Part D coverage gap. In addition, commencing in 2011, a new fee is being assessed on prescription drug manufacturers and importers that sell branded prescription drugs to specified U.S. government programs (e.g., Medicare and Medicaid). This fee is calculated based upon each entity’s relative share of total applicable branded prescription drug sales to specified U.S. government programs for the preceding calendar year. The aggregate industry wide fee is expected to total $28.0 billion through 2019, ranging from $2.5 billion to $4.1 billion annually. This new legislation did not have a material impact on our financial condition or results of operations in 2010; however, this legislation may have a material impact on our future business, cash flows, financial condition and results of operations with the addition of Valeant’s U.S. operations and the commencement in 2011 of the Medicaid Part D coverage gap and annual fee on branded prescription drugs programs. SELECTED FINANCIAL INFORMATION As described above under ‘‘Biovail Merger with Valeant’’, our results of operations, financial condition and cash flows reflect Biovail’s stand-alone operations as they existed prior to the completion of the Merger. The results of Valeant’s business have been included in our results of operations, financial condition and cash flows only for the period subsequent to the completion of the Merger. Therefore, our financial results for 2010 do not reflect a full year of Valeant’s operations. The following table provides selected financial information for each of the last three years: ($ in 000s, except per share data) Revenues . . . . . . . . . . . . . . . . Net income (loss) . . . . . . . . . . Basic and diluted earnings (loss) per share . . . . . . . . . . . . . . Cash dividends declared per Years Ended December 31 2010 $ 2009 $ 2008 $ $ Change 2009 to 2010 2008 to 2009 1,181,237 (208,193) 820,430 176,455 757,178 199,904 360,807 (384,648) % 44 (218) $ 63,252 (23,449) (1.06) 1.11 1.25 (2.17) (195) (0.14) % 8 (12) (11) (57) share . . . . . . . . . . . . . . . . . 1.280 0.645 1.500 0.635 98 (0.855) As of December 31 Change Total assets . . . . . . . . . . . . . . . . . Long-term debt, including current 10,795,117 2,059,290 1,623,565 8,735,827 2010 $ 2009 $ 2008 $ $ 2009 to 2010 2008 to 2009 % 424 $ 435,725 % 27 portion . . . . . . . . . . . . . . . . . . 3,595,277 326,085 — 3,269,192 1,003 326,085 NM NM — Not meaningful Financial Performance Changes in Revenues Total revenues increased $360.8 million, or 44%, to $1,181.2 million in 2010, compared with $820.4 million in 2009, primarily due to: • the addition of revenues from Valeant products and services of $274.6 million for the period from the Merger Date to December 31, 2010; 44 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) • an increase of $37.2 million in Xenazine(cid:4) product sales reflecting increased patient enrollment in the U.S. and the addition of rest-of-world sales following the tetrabenazine acquisition in June 2009; • an increase of $25.8 million in Wellbutrin XL(cid:4) product sales, mainly due to incremental revenue following the acquisition of the full U.S. commercialization rights in May 2009, partially offset by declines in prescription volumes due to generic competition; and • an increase of $20.6 million related to increased demand for our generic Tiazac(cid:4) product in the U.S., which was attributable to competitors’ manufacturing issues. Those factors were partially offset by: • a decline in Ultram(cid:4) ER and Cardizem(cid:4) LA product sales of $46.9 million in the aggregate, due to the impact of generic competition. Total revenues increased $63.3 million, or 8%, to $820.4 million in 2009, compared with $757.2 million in 2008, primarily due to: • an increase of $48.3 million in Wellbutrin XL(cid:4) product sales, mainly due to incremental revenue following the acquisition of the full U.S. commercialization rights in May 2009; • an increase of $44.7 million in Xenazine(cid:4) product sales, reflecting a full year’s contribution from sales in the U.S. and the addition of rest-of-world sales of these products following the tetrabenazine acquisition in June 2009; and • an increase of $10.2 million in sales of our generic Tiazac(cid:4) product in the U.S., attributable to competitors’ manufacturing issues. Those factors were partially offset by: • a decline of $27.9 million in Ultram(cid:4) ER product sales, as a result of the introduction of generic competition to the 100mg and 200mg dosage strengths in the fourth quarter of 2009; • a decline of $16.2 million in revenue from our portfolio of bioequivalent products in the U.S., due to overall reductions in the prices and volume for these products; and • a decline of $6.0 million in Cardizem(cid:4) LA product sales, due to lower inventory levels in the distribution channels in anticipation of the loss of market exclusivity. Changes in Net Income Net income declined $384.6 million to a net loss of $208.2 million (basic and diluted loss per share of $1.06) in 2010, compared with net income of $176.5 million (basic and diluted earnings per share (‘‘EPS’’) of $1.11) in 2009, reflecting the following factors: • the inclusion of $134.8 million of Merger-related restructuring charges and $38.3 million of Merger- related transaction costs in 2010; • a $115.0 million increase in amortization expense, primarily related to the identifiable intangible assets of Valeant ($86.4 million) and the Wellbutrin XL(cid:4) and tetrabenazine intangible assets (combined $28.5 million) acquired in May and June 2009, respectively; • a $59.4 million increase in interest expense, reflecting $47.8 million related to the assumed Valeant debt and the issuance of 6.875% Senior Notes due December 1, 2018 (the ‘‘2018 Notes’’) by Valeant in November 2010 (as described below under ‘‘Financial Condition, Liquidity and Capital Resources — Financial Assets (Liabilities)’’), and $12.1 million related to the issuance of 5.375% senior convertible notes due 2014 (the ‘‘5.375% Convertible Notes’’ and, together with the 4.0% Convertible Notes, the ‘‘Convertible Notes’’) in June 2009; 45 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) • the inclusion of a $52.6 million legal settlement charge in 2010, in connection with agreements or agreements in principle to settle certain Biovail legacy litigation matters; • the recognition of a $45.5 million valuation allowance against a portion of U.S. operating loss carryforwards as of the Merger Date (as described below under ‘‘Results of Operations — Income Taxes’’); • an increase of $42.9 million including $20.9 million recognized as of the Merger Date for the excess of the fair value of Biovail stock options and time-based RSUs over the fair value of converted Valeant awards, and approximately $17.0 million related to the amortization of the fair value increment on Valeant stock options and RSUs converted into Biovail awards; in non-restructuring-related share-based compensation, • a $32.4 million charge on the extinguishment of debt in 2010, mainly related to the repurchase of a portion of the 5.375% Convertible Notes and the cash settlement of the written call options on our common shares (as described below under ‘‘Results of Operations — Non-Operating Income (Expense) — Loss on Extinguishment of Debt’’). • a $29.9 million increase in acquired IPR&D, reflecting a $89.2 million charge in 2010 related to the istradefylline, AMPAKINE(cid:4) and Staccato(cid:4) the BVF-018 acquired IPR&D asset, compared with a $59.4 million charge in 2009 related to the acquisitions of the U.S. and Canadian rights to develop and commercialize fipamezole, pimavanserin and GDNF and the write-off of the acquired IPR&D asset related to the development of an isomer of tetrabenazine (RUS-350); and loxapine acquisitions and the write-off of • a decrease of $22.0 million related to a settlement in 2009 in respect of our investment in auction rate securities (as described below under ‘‘Results of Operations — Non-Operating Income (Expense) — Gain on Auction Rate Security Settlement’’). Those factors were partially offset by: • an increased contribution from product sales of $153.1 million, mainly related to the addition of Valeant product sales of $254.2 million (net of the incremental charge of $53.3 million to cost of goods sold from the sale of acquired inventory that was written up to fair value), increased Wellbutrin XL(cid:4), Xenazine(cid:4) and generic Tiazac(cid:4) product sales, and reduced costs and improved capacity utilization of our manufacturing operations. Those factors were partially offset by the reduction in Ultram(cid:4) ER and Cardizem(cid:4) LA product sales due to generic competition, and an increased supply price for Zovirax(cid:4) inventory (as described below under ‘‘Results of Operations — Expenses — Cost of Goods Sold’’); and • a $46.9 million reduction in the valuation allowance recorded against Canadian deferred tax assets in 2010 (as described below under ‘‘Results of Operations — Income Taxes’’). Net income declined $23.4 million, or 12%, to $176.5 million (basic and diluted EPS of $1.11) in 2009, compared with $199.9 million (basic and diluted EPS of $1.25) in 2008, reflecting the following factors: • a decline of $64.0 million in recognized net deferred income tax benefits, related to reductions in the valuation allowance recorded against U.S. operating loss carryforwards of $26.0 million and $90.0 million in the fourth quarters of 2009 and 2008, respectively (as described below under ‘‘Results of Operations — Income Taxes’’); • a $59.4 million IPR&D charge in 2009 in connection with the acquisitions of the various rights to develop and commercialize pimavanserin, fipamezole and GDNF, and the write-off of the RUS-350 acquired IPR&D asset; • a $53.4 million increase in amortization expense in 2009, primarily related to the acquired Wellbutrin XL(cid:4) and tetrabenazine intangible assets; and 46 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) • a $23.9 million increase in interest expense in 2009, mainly related to the issuance of the 5.375% Convertible Notes in June 2009. Those factors were partially offset by: • an increased contribution from product sales of $67.3 million in 2009, mainly related to the incremental revenue from Wellbutrin XL(cid:4), following the May 2009 acquisition of the full U.S. commercialization rights, and reduced costs and improved capacity utilization of our manufacturing operations; • a decline of $40.2 million in restructuring costs in 2009, mainly due to lower asset impairment charges; • a decline of $26.4 million in legal settlement charges in 2009, primarily related to the resolution of certain Biovail legacy governmental and regulatory inquiries in 2008, partially offset by $6.2 million accrued in 2009 in connection with the settlement of certain other litigation matters; • a decline of $22.2 million in internal research and development program expenses in 2009, reflecting reduced direct project spending as we transitioned from reformulation opportunities to the in-licensing, acquisition and development of specialty CNS products, and cost savings resulting from the closure of our Dublin, Ireland research and development facility; and • the auction rate security settlement gain of $22.0 million realized in 2009. Cash Dividends Prior to the Merger, we declared cash dividends per share of $0.28 in 2010, compared with $0.645 and $1.50 in 2009 and 2008, respectively. Following the Merger, we declared the post-Merger special dividend of $1.00 per share, which was paid on December 22, 2010 (as described above under ‘‘Biovail Merger with Valeant — Description of the Transaction’’). While our board of directors will review our dividend policy from time to time, we currently do not intend to pay dividends in the foreseeable future. Changes in Financial Condition As of December 31, 2010, we had cash and cash equivalents of $394.3 million and long-term debt of $3,595.3 million. Operating cash flows of $263.2 million were a significant source of liquidity in 2010, as well as net cash acquired on the acquisition of Valeant of $309.0 million. The cash component of the post-Merger special dividend amounted to $297.6 million and we paid pre-Merger cash dividends of $58.6 million in total. In addition, we paid $84.5 million, in the aggregate, mainly in connection with the ribavirin, Hamilton brands, istradefylline, AMPAKINE(cid:4) and Staccato(cid:4) loxapine acquisitions. In November 2010, we issued $1.0 billion aggregate principal amount of 2018 Notes. A portion of the net proceeds was used to repay the remaining $500.0 million owed under the Term Loan B Facility. In the fourth quarter of 2010, part of the remaining proceeds were used for securities repurchases, including $126.3 million principal amount of the 5.375% Convertible Notes for consideration of $259.2 million and 2.3 million of our common shares for consideration of $60.1 million. On February 8, 2011, we issued $650.0 million aggregate principal amount of 6.75% Senior Notes due 2021 (the ‘‘2021 Notes’’), which proceeds are expected to be used to finance the acquisitions of PharmaSwiss and the U.S. and Canadian rights to non-ophthalmic topical formulations of Zovirax(cid:4) (as described below under ‘‘Financial Condition, Liquidity and Capital Resources — Financial Assets (Liabilities)’’). 47 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) RESULTS OF OPERATIONS Business Segments Effective with the Merger, we operate in the following business segments, based on differences in products and services and geographical areas of operations: • U.S. Neurology and Other consists of sales of pharmaceutical and OTC products indicated for the treatment of neurological and other diseases, as well as alliance revenue from the licensing of various products we developed or acquired. In addition, this segment includes revenue from contract research services provided by CRD prior to its disposal in July 2010. • U.S. Dermatology consists of pharmaceutical and OTC product sales, and alliance and contract service revenues in the areas of dermatology and topical medication. • Canada and Australia consists of pharmaceutical and OTC products sold in Canada, Australia and New Zealand. • Branded Generics — Europe consists of branded generic pharmaceutical products sold primarily in Poland, Hungary, the Czech Republic and Slovakia. • Branded Generics — Latin America consists of branded generic pharmaceutical and OTC products sold primarily in Mexico, Brazil and exports out of Mexico to other Latin American markets. Revenues By Segment Our primary sources of revenues are the sale of pharmaceutical and OTC products; the out-licensing of products; and contract services. The following table displays revenues by segment for each of the last three years, the percentage of each segment’s revenues compared with total revenues in the respective year, and the dollar and percentage change in the dollar amount of each segment’s revenues. Percentages may not add due to rounding. ($ in 000s) U.S. Neurology and Other(2) . . . . . . . . . . . . U.S. Dermatology(3) . . . . . . . . . . . . . . . . . Canada and Australia(4) . . . . . . . . . . . . . . . Branded Generics — Europe(5) . . . . . . . . . . . Branded Generics — Latin America . . . . . . . Years Ended December 31 Change 2010(1) $ 658,312 219,008 161,568 73,312 69,037 % 56 19 14 6 6 2009 $ 575,321 146,267 83,959 14,883 — 2008 2009 to 2010 2008 to 2009 % 70 18 10 2 — $ 525,939 150,613 73,764 6,862 — % 69 20 10 1 — $ % $ % 14 82,991 50 72,741 92 77,609 58,429 393 69,037 NM 49,382 (4,346) 10,195 8,021 — 9 (3) 14 117 — Total revenues . . . . . . . . . . . . . . . . . . . . . 1,181,237 100 820,430 100 757,178 100 360,807 44 63,252 8 (1) Reflects incremental revenues from Valeant products and services commencing on the Merger Date as follows: U.S. Neurology and Other — $60.8 million; U.S. Dermatology — $57.2 million; Canada and Australia — $47.6 million; Branded Generics — Europe — $40.0 million; and Branded Generics — Latin America — $69.0 million. (2) (3) (4) (5) Includes sales of Wellbutrin XL(cid:4), Xenazine(cid:4), Ultram(cid:4) ER, Cardizem(cid:4) LA, Cardizem(cid:4) CD and Tiazac(cid:4) products, and bioequivalent versions of Cardizem(cid:4) CD, Procardia XL and Adalat CC products. Includes sales of Zovirax(cid:4) products. Includes sales of Wellbutrin(cid:4) XL, Tiazac(cid:4) and Glumetza(cid:4) products. Includes sales of Xenazine(cid:4) and Wellbutrin XL(cid:4) products in countries outside of the U.S. and Canada. 48 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Total revenues increased $360.8 million, or 44%, to $1,181.2 million in 2010, compared with $820.4 million in 2009, and increased $63.3 million, or 8%, in 2009, compared with $757.2 million in 2008. A substantial portion of the increase in 2010 was due to incremental revenues from Valeant products and services of $274.6 million, while the remaining year-over-year increase in 2010 and the year-over-year increase in 2009 reflected the following results from other of our products: • in the U.S. Neurology and Other segment: • an increase in Xenazine(cid:4) product sales of $27.2 million, or 61%, to $71.8 million in 2010, compared with $44.6 million in 2009, and an increase of $40.9 million in 2009, compared with $3.7 million in 2008, reflecting year-over-year increases in patient enrollment in the U.S., following the product’s launch in December 2008; • an increase in Wellbutrin XL(cid:4) product sales of $25.8 million, or 16%, to $188.0 million in 2010, compared with $162.2 million in 2009, and an increase of $48.3 million, or 42%, in 2009, compared with incremental revenue of approximately $50.0 million and $113.9 million $109.0 million full respectively, U.S. commercialization rights in May 2009, and the positive effect of subsequent price increases, partially offset by the declines in prescription volumes due to generic competition; and in 2010 and 2009, the acquisition of in 2008, reflecting following the • an increase in sales of generic Tiazac(cid:4) of $20.6 million, or 118%, to $38.0 million in 2010, compared with $17.4 million in 2009, and an increase of $10.2 million, or 140%, in 2009, compared with $7.3 million in 2008, which was attributable to competitors’ manufacturing issues. Those factors were partially offset by: • a decline in Ultram(cid:4) ER product sales of $28.8 million, or 53%, to $25.2 million in 2010, compared with $54.0 million in 2009, and a decline of $27.9 million, or 34%, in 2009, compared with $81.9 million in 2008, reflecting the impact on volumes due to the introduction of generic competition to the 100mg and 200mg dosage strengths in November 2009 (which also had some negative impact on sales of the 300mg dosage strength). In addition, upon generic entry, our contractual supply price for branded 100mg and 200mg Ultram(cid:4) ER products was reduced by 50%. As there is currently no generic equivalent to the 300mg Ultram(cid:4) ER product, our supply price for that dosage strength remains unchanged. All of those factors were partially offset by revenue generated through our supply of 100mg and 200mg authorized generic versions of Ultram(cid:4) ER; and • a decline in revenue from sales of Cardizem(cid:4) LA of $18.1 million, or 43%, to $23.9 million in 2010, compared with $42.0 million in 2009, and a decline of $6.0 million, or 12%, in 2009, compared with $48.0 million in 2008, reflecting lower volumes as a result of the introduction of a generic version of Cardizem(cid:4) LA (in all dosage strengths except 120mg) by a competitor in March 2010. We are entitled to a royalty based on net sales of the competitor’s generic version of Cardizem(cid:4) LA. • in the U.S. Dermatology segment: • an increase in Zovirax(cid:4) product sales of $15.5 million, or 11%, to $161.8 million in 2010, compared with $146.3 million in 2009, reflecting price increases implemented for this product during 2010, which more than offset lower prescription volumes, due in part to increasing competition from oral therapies. • in the Canada and Australia segment: • an increase in combined sales of Wellbutrin(cid:4) XL, Tiazac(cid:4) and Glumetza(cid:4) products in Canada of $31.9 million, or 49%, to $96.9 million in 2010, compared with $65.0 million in 2009, and an increase of $7.3 million, or 13%, in 2009, compared with $57.7 million in 2008, reflecting increased prescription volumes for our promoted Wellbutrin(cid:4) XL and Tiazac(cid:4) XC brands, as well as increased demand for 49 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) our branded Tiazac(cid:4) product, which was attributable to competitors’ manufacturing issues. In addition, sales of Glumetza(cid:4) in the 2010 benefited from a delay in the introduction of a competing generic version of the 500mg dosage strength. • in the Branded Generics — Europe segment: • incremental Xenazine(cid:4) revenues of $13.8 million and $3.8 million in 2010 and 2009, respectively, following the acquisition of the worldwide commercialization and development rights to tetrabenazine in June 2009. Segment Profit Segment profit is based on operating income after the elimination of intercompany transactions. Certain costs, such as restructuring and acquisition-related costs and legal settlement and acquired IPR&D charges, are not included in the measure of segment profit, as management excludes these items in assessing financial performance. In addition, share-based compensation is not allocated to segments, since the amount of such expense depends on company-wide performance rather than the operating performance of any single segment. The following table displays profit (loss) by segment for each of the last three years, the percentage of each segment’s profit (loss) compared with corresponding segment revenues in the respective year, and the dollar and percentage change in the dollar amount of each segment’s profit (loss). Percentages may not add due to rounding. ($ in 000s) 2010(1) $ U.S. Neurology and Other . . . . . . . . . . . . . . . . . U.S. Dermatology . . . . . . . . . . . . . . . . . . . . . . Canada and Australia . . . . . . . . . . . . . . . . . . . . Branded Generics — Europe . . . . . . . . . . . . . . . Branded Generics — Latin America . . . . . . . . . . . 251,129 47,737 51,043 20,646 (3,889) Total segment profit . . . . . . . . . . . . . . . . . . . . . 366,666 Years Ended December 31 Change 2009 $ 274,548 87,860 35,037 9,152 — 406,597 % 48 60 42 61 — 50 % 38 22 32 28 (6) 31 2008 $ 243,180 93,475 15,171 3,553 — 355,379 % 46 62 21 52 — 47 2009 to 2010 2008 to 2009 $ % $ % (9) (23,419) (46) (40,123) 46 16,006 11,494 126 (3,889) NM 31,368 (5,615) 19,866 5,599 — 13 (6) 131 158 — (39,931) (10) 51,218 14 (1) Segment profit (loss) reflects addition of Valeant’s operations commencing on the Merger Date, including the impact of acquisition accounting adjustments related to inventory and identifiable intangible assets as follows: U.S. Neurology and Other — $33.1 million; U.S. Dermatology — $27.4 million; Canada and Australia — $17.0 million; Branded Generics — Europe — $12.9 million; and Branded Generics — Latin America — $21.6 million. Total segment profit declined $39.9 million, or 10%, to $366.7 million in 2010, compared with $406.6 million in 2009, mainly attributable to the net effect of the following factors: • in the U.S. Neurology and Other segment: • reduced revenues and contribution from Ultram(cid:4) ER and Cardizem(cid:4) LA product sales due to generic competition; and • a lower contribution from our portfolio of bioequivalent products due to higher rebates in the amount of $19.1 million in 2010. Those factors were partially offset by: • increased revenues and contribution from sales of Wellbutrin XL(cid:4) (reflecting the incremental revenue following the acquisition of the full U.S. commercialization rights in May 2009) and Xenazine(cid:4) (reflecting the increase in patient enrollment in the U.S.). 50 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) • in the U.S. Dermatology segment: • a reduced contribution from Zovirax(cid:4) product sales due to an increased supply price for inventory purchased from GSK, as a result of the conclusion of a price allowance that had entitled us to purchase a pre-determined quantity of Zovirax(cid:4) inventory at reduced prices; however, following the closing of the acquisition of all U.S. rights to non-ophthalmic topical formulations of Zovirax(cid:4) (as described above under ‘‘Acquisitions — Zovirax(cid:4)), we will retain a greater share of the economic interest in this brand; • in the Canada and Australia segment: • increased revenues and contribution from Wellbutrin(cid:4) XL and Tiazac(cid:4) product sales in Canada reflecting increased prescription volumes for our promoted Wellbutrin(cid:4) XL and Tiazac(cid:4) XC brands, as well as increased demand for our branded Tiazac(cid:4) product, which was attributable to competitors’ manufacturing issues. • in the Branded Generics — Europe segment: • increased revenues and contribution from Xenazine(cid:4) product sales, following the acquisition of the worldwide commercialization and development rights to tetrabenazine in June 2009. Total segment profit increased $51.2 million, or 14%, to $406.6 million in 2009, compared with $355.4 million in 2008, mainly attributable to the net effect of the following factors: • in the U.S. Neurology and Other segment: • increased revenues and contribution from sales of Wellbutrin XL(cid:4) (reflecting the incremental revenue following the acquisition of the full U.S. commercialization rights in May 2009) and Xenazine(cid:4) (reflecting the first full-year of sales, following the product’s launch in November 2008). That factor was partially offset by: • reduced revenues and contribution from Ultram(cid:4) ER and Cardizem(cid:4) LA product sales due to generic competition. • in the Canada and Australia segment: • lower selling, general and administrative expenses related to the reversal in 2009 of a $10.1 million potential voluntary compliance undertaking liability, as a result of the closure of an investigation into the introductory pricing of Glumetza(cid:4) in Canada, which determined that our prices for the 500mg and 1000mg dosage strengths were appropriate; and • increased revenues and contribution from our promoted Wellbutrin(cid:4) XL and Tiazac(cid:4) XC brands. 51 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Operating Expenses The following table displays the dollar amount of each operating expense category for each of the last three years, the percentage of each category compared with total revenues in the respective year, and the dollar and percentage changes in the dollar amount of each category. Percentages may not add due to rounding. Years Ended December 31 Change 2010 2009 2008 2009 to 2010 2008 to 2009 ($ in 000s) $ % $ Cost of goods sold (exclusive of amortization of intangible assets shown separately below) . . . Cost of services . . . . . . . . . . . . . . . . . . . . . Research and development . . . . . . . . . . . . . . Selling, general and administrative . . . . . . . . . Amortization of intangible assets . . . . . . . . . . Restructuring and other costs . . . . . . . . . . . . Acquired IPR&D . . . . . . . . . . . . . . . . . . . . Legal settlements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Acquisition-related costs 395,595 10,155 68,311 276,546 219,758 140,840 89,245 52,610 38,262 33 1 6 23 19 12 8 4 3 204,309 13,849 47,581 167,633 104,730 30,033 59,354 6,191 5,596 Total operating expenses . . . . . . . . . . . . . . . 1,291,322 109 639,276 % 25 2 6 20 13 4 7 1 1 78 $ 197,167 23,033 69,811 188,922 51,369 70,202 — 32,565 — 633,069 % 26 3 9 25 7 9 — 4 — 84 $ % $ % 191,286 (3,694) 20,730 108,913 115,028 110,807 29,891 46,419 32,666 94 (27) 44 65 110 369 50 750 584 4 7,142 (40) (9,184) (32) (22,230) (11) (21,289) 104 53,361 (40,169) (57) 59,354 NM (81) (26,374) 5,596 NM 652,046 102 6,207 1 NM — Not meaningful Cost of Goods Sold Cost of goods sold includes: manufacturing and packaging; the cost of products we purchase from third parties; royalty payments we make to third parties; depreciation of manufacturing facilities and equipment; and lower of cost or market adjustments to inventories. Cost of goods sold excludes the amortization of intangible assets described separately below under ‘‘— Amortization of Intangible Assets’’. Cost of goods sold increased $191.3 million, or 94%, to $395.6 million in 2010, compared with $204.3 million in 2009. The percentage increase in cost of goods sold was higher than the corresponding 44% increase in total product sales in 2010, primarily due to: • the addition of the cost of Valeant’s product sales of $138.1 million, including the impact of the acquisition accounting adjustment of $53.3 million to Valeant inventory that was subsequently sold in the fourth quarter of 2010; • the increased supply price for Zovirax(cid:4) inventory purchased from GSK, as a result of the conclusion of the price allowance in 2010; • the impact of higher rebates ($19.1 million) on our portfolio of bioequivalent product in 2010; • the increase in lower margin Xenazine(cid:4) product sales; • the negative impact on Ultram(cid:4) ER product sales of the reduction in our contractual supply price for the 100mg and 200mg dosage strengths; and • the negative impact on labour and overhead costs at our Canadian manufacturing facilities, as a result of the strengthening of the Canadian dollar relative to the U.S. dollar. Those factors were partially offset by: • lower labour and overhead costs at our Puerto Rico manufacturing facilities and higher absorption at our Steinbach, Manitoba facility, each of which was a result of the transfer of manufacturing activities from the Puerto Rico facilities to the Steinbach facility; 52 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) • an increased contribution from higher margin Wellbutrin XL(cid:4) product sales following the acquisition of the full U.S. commercialization rights in May 2009; • a higher cost basis related to the $10.5 million of Wellbutrin XL(cid:4) inventory reacquired from GSK in connection with the acquisition of the full U.S. commercialization rights, and sold to our wholesale customers in the second quarter of 2009; and • the positive impact of price increases implemented during 2010. Cost of goods sold increased $7.1 million, or 4%, to $204.3 million in 2009, compared with $197.2 million in 2008. The percentage increase in cost of goods sold was less than the corresponding 10% increase in total product sales in 2009, primarily due to: • lower labour and overhead costs at our Puerto Rico manufacturing facilities, and higher absorption at our Steinbach, Manitoba manufacturing facility, as a result of the transfer of certain manufacturing activities; • an increased contribution from higher margin Wellbutrin XL(cid:4) product sales following the acquisition of the full U.S. commercialization rights in May 2009; • the positive impact of price increases implemented in 2009; and • the positive impact on labour and overhead costs at the Steinbach facility as a result of the weakening of the Canadian dollar relative to the U.S. dollar. Those factors were partially offset by: • the inclusion of lower margin Xenazine(cid:4) product sales; • a higher cost basis related to the Wellbutrin XL(cid:4) inventory reacquired from GSK; • a decline in volume of higher margin Wellbutrin XL(cid:4) product sales, as a result of the introduction of generic competition in May 2008; • the reduction in our contractual supply price for Ultram(cid:4) ER and an increase in the provision for expected returns of the product as a result of generic entry; and • costs associated with the transfer of certain manufacturing and packaging processes from the Puerto Rico facilities to the Steinbach facility, partially offset by lower depreciation expense as a result of the write-down of the property, plant and equipment located in Puerto Rico. Cost of Services Cost of services reflects the costs associated with providing contract services to external customers. Cost of services declined $3.7 million, or 27%, to $10.2 million in 2010, compared with $13.8 million in 2009, and declined $9.2 million, or 40%, in 2009, compared with $23.0 million in 2008, primarily due to: • a decline in activity levels at CRD prior to its disposal in July 2010, and lower labour costs as a result of headcount reductions at CRD in the second quarter of 2009 and the fourth quarter of 2008. That factor was partially offset by: • the inclusion of the cost of Valeant’s contract service operations of $2.9 million in the areas of dermatology and topical medication from the Merger Date. Research and Development Expenses Expenses related to research and development programs include: employee compensation costs; overhead and occupancy costs; depreciation of research and development facilities and equipment; clinical trial costs; clinical manufacturing and scale-up costs; and other third-party development costs. 53 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Research and development expenses increased $20.7 million, or 44%, to $68.3 million in 2010, compared with $47.6 million in 2009, reflecting the addition of Valeant’s operating costs of $13.0 million and higher direct project spending on our specialty CNS drug-development programs prior to the Merger. As described above under ‘‘Restructuring and Integration — Merger-Related Cost-Rationalization and Integration Initiatives — Research and Development Pipeline Rationalization’’, we have assessed our product development pipeline and have decided not to continue a number of these specialty CNS programs. In addition, prior to the Merger, we cancelled the Phase 3 clinical trials that were underway in Europe for BVF-324 (the use of non-commercially available doses of tramadol for the treatment of premature ejaculation), due to slower-than-anticipated enrolment and a lack of commercial interest in the product, and recognized the contractual obligations related to the termination of these studies. Research and development program expenses declined $22.2 million, or 32%, to $47.6 million in 2009, compared with $69.8 million in 2008, reflecting reduced direct project spending as we transitioned from reformulation opportunities to the in-licensing, acquisition and development of specialty CNS products, and cost savings as a result of the closures of our Dublin, Ireland and Mississauga, Ontario research and development facilities. Also contributing to the year-over-year decline in 2009 was the recognition in 2008 of $7.9 million in costs related to the termination of the BVF-146 program to develop a combination of tramadol and a non-steroidal anti-inflammatory drug. Selling, General and Administrative Expenses Selling, general and administrative expenses include: employee compensation costs associated with sales and marketing, finance, legal, information technology, human resources, and other administrative functions; outside legal fees and consultancy costs; product promotion expenses; overhead and occupancy costs; depreciation of corporate facilities and equipment; and other general and administrative costs. Selling, general and administrative expenses increased $108.9 million, or 65%, to $276.5 million in 2010, compared with $167.6 million in 2009, primarily due to: • the addition of Valeant’s operating costs of $74.1 million; • the inclusion of $20.1 million of share-based compensation expense as of the Merger Date, related to vested and partially vested Valeant stock options and RSUs converted into Biovail awards, and the addition of approximately $17.0 million of incremental share-based compensation expense, related to the amortization of the fair value increment on Valeant stock options and RSUs converted into Biovail awards; • an increase in compensation expense related to deferred share units (‘‘DSUs’’) granted to directors of $6.0 million, which reflected the impact of year-over-year increases in the underlying trading price of our common shares; and • the negative impact of the strengthening of the Canadian dollar relative to the U.S. dollar. Those factors were partially offset by: • a decrease of $17.7 million in indemnification obligations to, and costs incurred by, certain former officers and directors of Biovail, in connection with regulatory proceedings involving these individuals. Selling, general and administrative expenses declined $21.3 million, or 11%, to $167.6 million in 2009, compared with $188.9 million in 2008, primarily due to: • a decrease of $10.1 million related to the reversal in 2009 of the voluntary compliance undertaking liability for Glumetza(cid:4) in Canada; • a decrease of $7.4 million related to management succession costs, associated primarily with a change in our Chief Executive Officer in May 2008; 54 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) • a decrease in proxy contest costs of $5.2 million, primarily reflecting expenses incurred in 2008 in connection with the contested election of our nominees to the board of directors at our 2008 annual meeting of shareholders; • a decrease of $4.1 million related to consulting costs incurred in 2008 related to the development and implementation of our former specialty CNS strategy; and • the positive effects of the weakening of the Canadian dollar relative to the U.S. dollar and overall cost containment initiatives. Those factors were partially offset by: • an increase in legal fees of $3.8 million, primarily related to indemnification obligations to certain former officers and directors. Amortization of Intangible Assets Amortization expense increased $115.0 million, or 110%, to $219.8 million in 2010, compared with $104.7 million in 2009, due to the inclusion of amortization of the Valeant identifiable intangible assets ($86.4 million), as well as the Wellbutrin XL(cid:4) trademark intangible asset acquired in May 2009 and the product rights intangible assets arising from the tetrabenazine acquisition in June 2009. Amortization expense increased $53.4 million, or 104%, to $104.7 million in 2009, compared with $51.4 million in 2008, due to the inclusion of amortization of the Wellbutrin XL(cid:4) trademark and tetrabenazine product rights intangible assets. Restructuring and Other Costs As described above under ‘‘Restructuring and Integration — Merger-Related Cost-Rationalization and Integration Initiatives and — Pre-Merger Cost-Rationalization Initiatives’’, we recorded a restructuring charge of $140.8 million in 2010, compared with $30.0 million and $70.2 million in 2009 and 2008, respectively. Acquired IPR&D Acquired IPR&D represents compounds, new indications, or line extensions under development that have not received regulatory approval for marketing at the time of acquisition. IPR&D acquired through an asset acquisition is written-off at the acquisition date if the assets have no alternative future use. IPR&D acquired in a business combination is capitalized as indefinite-lived intangible assets (irrespective of whether these assets have an alternative future use) until completion or abandonment of the related research and development activities. Costs associated with the development of acquired IPR&D assets are expensed as incurred. In 2010, we recorded a charge of $89.2 million related to the istradefylline, AMPAKINE(cid:4) and Staccato(cid:4) loxapine acquisitions ($61.2 million) and the write-off the BVF-018 acquired IPR&D asset ($28.0 million). In 2009, we recorded a $59.4 million charge related to the acquisitions of the various rights to pimavanserin, fipamezole and GDNF, as well as the write-off of the $8.0 million acquired IPR&D asset related to RUS-350 upon termination of this project. Legal Settlements In 2010, 2009 and 2008, we recorded legal settlement charges of $52.6 million, $6.2 million and $32.6 million, respectively, in connection with agreements or agreements in principle to settle certain Biovail legacy litigation and regulatory matters. 55 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Acquisition-Related Costs As described above under ‘‘Biovail Merger with Valeant — Acquisition-Related Costs’’, we incurred $38.3 million of Merger-related transaction costs in 2010. In 2009, we incurred costs of $5.6 million in connection with the tetrabenazine acquisition. Non-Operating Income (Expense) The following table displays each non-operating income or expense category for each of the last three years, and the dollar and percentage changes in the dollar amount of each category. ($ in 000s; Income (Expense)) Interest income . . . . . . . . . . . . . . . . . . . . Interest expense . . . . . . . . . . . . . . . . . . . . Write-down of deferred financing costs . . . Foreign exchange and other . . . . . . . . . . . Loss on extinguishment of debt . . . . . . . . Loss on auction rate securities . . . . . . . . . Gain on auction rate security settlement . . Gain on disposal of investments . . . . . . . . Impairment loss on equity securities . . . . . Equity loss . . . . . . . . . . . . . . . . . . . . . . . Years Ended December 31 2010 $ 2009 $ 2008 $ Change 2009 to 2010 $ % 2008 to 2009 $ % 1,294 (84,307) (5,774) 574 1,118 (24,881) 9,400 (1,018) (537) — 507 (32,413) — (5,552) — — — — — — (5,210) 22,000 804 (1,057) — (8,613) — 6,534 (1,256) (1,195) 176 (59,426) (5,237) 67 16 239 975 13 (32,413) NM 7 (100) (100) — — (342) (22,000) (804) — — (8,282) (88) (23,863) 2,344 (537) NM (148) 1,564 — — (40) 3,403 NM 22,000 (88) (5,730) (100) 1,256 (100) 1,195 Total non-operating income (expense) . . . . (126,178) (6,199) 2,795 (119,979) 1,935 (8,994) (322) NM — Not meaningful Interest Expense Interest expense increased $59.4 million, or 239%, to $84.3 million in 2010, compared with $24.9 million in 2009, reflecting $47.8 million related to the assumed Valeant debt and the 2018 Notes issued in November 2010, and $12.1 million related to the issuance of the 5.375% Convertible Notes in June 2009. Interest expense in 2010 includes non-cash amortization of debt discounts and deferred financing costs of $21.5 million, in the aggregate. Interest expense increased $23.9 million to $24.9 million in 2009, compared with $1.0 million in 2008, mainly related to the 5.375% Convertible Notes issued in June 2009. Loss on Extinguishment of Debt In November and December 2010, we repurchased $126.3 million aggregate principal amount of the 5.375% Convertible Notes for an aggregate purchase price of $259.2 million (of which $4.9 million related to the payment of accreted interest). The carrying amount of the 5.375% Convertible Notes purchased was $106.9 million (net of $3.9 million of related unamortized deferred financing costs) and the estimated fair value of the 5.375% Convertible Notes exclusive of the conversion feature was $127.5 million. The difference of $20.7 million between the net carrying amount and the estimated fair value was recognized as a loss on extinguishment of debt. The difference of $131.7 million between the estimated fair value of $127.5 million and the purchase price of $259.2 million was charged to shareholders’ equity. In addition, the loss on extinguishment of debt includes the loss of $10.1 million related to the cash settlement of the written call options on our common shares. 56 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Loss on Auction Rate Securities In August 2010, we disposed of our entire portfolio of auction rate securities for cash proceeds of $1.4 million and recorded a loss related to an other-than-temporary decline in the estimated fair value these securities of $5.6 million in 2010, compared with $5.2 million and $8.6 million in 2009 and 2008, respectively. Gain on Auction Rate Security Settlement In May 2009, we received $22.0 million to settle an arbitration with the investment bank that invested our assets in auction rate securities. Income Taxes The following table displays the dollar amount of the current and deferred provisions for income taxes for each of the last three years, and the dollar and percentage changes in the dollar amount of each provision. Percentages may not add due to rounding. % 89 246 $ % 2,500 (74,000) (15) (82) ($ in 000s; Income (Expense)) Years Ended December 31 2010 $ 2009 $ 2008 $ $ Change 2009 to 2010 2008 to 2009 Current income tax expense . . . . . . . . . . . . . Deferred income tax benefit . . . . . . . . . . . . . (27,333) 55,403 (14,500) 16,000 (17,000) 90,000 (12,834) 39,404 Total recovery of income taxes . . . . . . . . . . . 28,070 1,500 73,000 26,570 1,771 (71,500) (98) In 2010, our effective tax rate was impacted by (i) the recording of a $45.5 million valuation allowance against a portion of the net deferred tax asset in respect of our U.S. tax loss carryforwards; (ii) the release of a $46.9 million valuation allowance against a portion of the deferred tax assets in respect of our Canadian tax loss carryforwards, scientific research and experimental development pool, and investment tax credits; (iii) the non-deductible portion of the acquisition-related costs related to the Merger; (iv) the non-deductible portion of the acquired IPR&D charges associated with the istradefylline, AMPAKINE(cid:4), and Staccato(cid:4) loxapine acquisitions, and the impairment charge for BVF-018, recognized in a jurisdiction with lower statutory tax rates than those that apply in Canada; and (v) provisions for legal settlements in jurisdictions with lower statutory rates than those that apply in Canada, or where a full valuation allowance is recorded against tax loss carryforwards. The Merger resulted in tax loss carryforwards of Biovail’s U.S. group becoming subject to the ownership change limitations of the U.S. Internal Revenue Code and similar state legislation. In each of the fourth quarters of 2009 and 2008, we assessed the realizability of a portion of our deferred tax assets related to operating loss carryforwards in the U.S. Biovail’s U.S. group had generated positive earnings in each fiscal year commencing with 2006, reflecting a reduction in the overall cost structure, including the elimination of Biovail’s U.S. sales force, through restructuring measures implemented in 2006 and 2005. As a result, we reduced the valuation allowance recorded against available U.S. operating loss carryforwards by $26.0 million and $90.0 million in the fourth quarters of 2009 and 2008, respectively, with corresponding increases to net income. In determining the amount of the valuation allowance that was necessary, we considered the amount of operating loss carryforwards that we would more likely than not be able to utilize based on the taxable income expected to be generated in the U.S. in future years. In 2009, we recorded a provision for deferred income taxes of $10.0 million related to the utilization of a portion of these loss carryforwards to reduce taxable income in the U.S. 57 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) SUMMARY OF QUARTERLY RESULTS (UNAUDITED) The following table presents a summary of our unaudited quarterly results of operations and operating cash flows in 2010 and 2009: ($ in 000s, except per share data) 2010 Q1 $ Q2 $ Q3 $ Q4 $ Q1 $ 2009 Q2 $ Q3 $ Q4 $ Revenue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219,635 238,771 Expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203,268 189,959 208,267 514,564 173,319 193,535 212,523 241,053 334,579 563,516 119,704 182,988 154,179 182,405 Operating income (loss) . . . . . . . . . . . . . . . . . . . . . . . . . 16,367 48,812 (126,312) (48,952) 53,615 10,547 58,344 58,648 Net income (loss) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (3,150) 33,969 (207,882) (31,130) 39,003 24,090 40,362 73,000 Basic and diluted earnings (loss) per share . . . . . . . . . . . . . (0.02) 0.21 (1.27) (0.10) 0.25 0.15 0.25 0.46 Net cash provided by (used in) operating activities . . . . . . . . 44,753 108,913 110,924 (1,399) 46,972 97,081 89,197 127,647 Fourth Quarter of 2010 Compared to Fourth Quarter of 2009 Results of Operations Total revenues increased $273.5 million, or 113%, to $514.6 million in the fourth quarter of 2010, compared with $241.1 million in the fourth quarter of 2009, reflecting the inclusion of revenues from Valeant’s products and services of $274.6 million. Net income declined $104.1 million, or 143%, to a net loss of $31.1 million in the fourth quarter of 2010, compared with net income of $73.0 million in the fourth quarter of 2009, reflecting the following factors: • an increase in amortization expense of $83.3 million, reflecting amortization of the Valeant identifiable intangible assets ($84.1 million); • an increase of $43.3 million in interest expense, mainly related to the assumed Valeant debt and the issuance of the 2018 Notes in November 2010; • the charge of $32.4 million on extinguishment of debt in the fourth quarter of 2010, related to the repurchase of a portion of the 5.375% Convertible Notes and the cash settlement of the written call options on our common shares; • an increase in restructuring charges of $26.5 million, mainly in connection with Merger-related cost-rationalization and integration initiatives; • the reduction in the valuation allowance against a portion of U.S. operating loss carryforwards of $26.0 million recorded in the fourth quarter of 2009; and • an increase of $21.0 million in non-restructuring-related share-based compensation expense, including approximately $17.0 million related to the amortization of the fair value increment on Valeant stock options and RSUs converted into Biovail awards. Those factors were partially offset by: • an increased contribution from product sales of $105.2 million, mainly related to the addition of Valeant’s products (net of the impact of the acquisition accounting adjustment of $53.3 million to Valeant inventory that was subsequently sold in the fourth quarter of 2010); and • the $46.9 million reduction in the valuation allowance recorded against Canadian deferred tax assets in the fourth quarter of 2010. 58 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Cash Flows Net cash used in operating activities was $1.4 million in the fourth quarter of 2010, compared with net cash provided of $127.6 million in the fourth quarter of 2009, reflecting a decline of $129.0 million, primarily due to: • payments related to the Merger-related restructuring charges ($54.3 million) and legal settlement payments related to Biovail legacy litigation matters ($38.5 million); and • the timing of other receipts and payments in the ordinary course of business. FINANCIAL CONDITION, LIQUIDITY AND CAPITAL RESOURCES Selected Measures of Financial Condition The following table presents a summary of our financial condition as of December 31, 2010 and 2009: ($ in 000s; Asset (Liability)) As of December 31 2010 $ 2009 $ Change $ % Cash and cash equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . Long-lived assets(1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Long-term debt, including current portion . . . . . . . . . . . . . . . . Shareholders’ equity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394,269 9,655,908 (3,595,277) (4,911,096) 114,463 1,539,364 (326,085) (1,354,372) 279,806 244 527 8,116,544 (3,269,192) 1,003 263 (3,556,724) (1) Long-lived assets comprise property, plant and equipment, intangible assets and goodwill. Cash and Cash Equivalents Cash and cash equivalents increased $279.8 million, or 244%, to $394.3 million as of December 31, 2010, compared with $114.5 million at December 31, 2009, which primarily reflected the following sources of cash: • $992.4 million of net proceeds on the issuance of the 2018 Notes; • $309.0 million in net cash acquired on the acquisition of Valeant; • $263.2 million in operating cash flows; and • $58.4 million in proceeds from stock option exercises. Partially offset by the following uses of cash: • repayment of $500.0 million of the Term Loan B Facility, $25.0 million of the Term Loan A Facility and $12.5 million paid on account of the obligation to Cambridge Laboratories (Ireland) Limited (‘‘Cambridge’’) in connection with the tetrabenazine acquisition; • $356.3 million paid in dividends; • $259.2 million paid to repurchase a portion of the 5.375% Convertible Notes (including the payment of accreted interest of $4.9 million); • $84.5 million paid, in the aggregate, mainly in respect of the ribavirin, Hamilton brands, istradefylline, AMPAKINE(cid:4) and Staccato(cid:4) loxapine acquisitions; and • $60.1 million related to the repurchase of common shares. 59 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Long-Lived Assets Long-lived assets increased $8,116.5 million, or 527%, to $9,655.9 million as of December 31, 2010, compared with $1,539.4 million at December 31, 2009, primarily due to: • the inclusion of the acquired long-lived tangible and intangible assets and goodwill of Valeant of $8,312.9 million in the aggregate (as described above under ‘‘Biovail Merger with Valeant — Assets Acquired and Liabilities Assumed’’). That factor was partially offset by: • the depreciation of plant and equipment and amortization of intangible assets of $252.9 million in the aggregate. Long-term Debt Long-term debt (including the current portion) increased $3,269.2 million to $3,595.3 million as of December 31, 2010, compared with $326.1 million at December 31, 2009, primarily due to: • the inclusion of the assumed long-term debt of Valeant of $2,913.6 million (as described above under ‘‘Biovail Merger with Valeant — Assets Acquired and Liabilities Assumed’’); and • the issuance of $992.4 million principal amount of 2018 Notes, net of discount. Those factors were partially offset by: • the repayment of $537.5 million, in the aggregate, of the Term Loan B Facility, Term Loan A Facility and Cambridge obligation; and • the repurchase of $110.8 million carrying amount of the 5.375% Convertible Notes (exclusive of related deferred financing costs). Shareholders’ Equity Shareholders’ equity increased $3,556.7 million, or 263%, to $4,911.1 million as of December 31, 2010, compared with $1,354.4 million at December 31, 2009, primarily due to: • the issuance of equity of $3,880.3 million to finance the acquisition of Valeant and the aggregate value of $254.0 million assigned to the equity component of the assumed 4.0% Convertible Notes and call option agreements of Valeant (as described above under ‘‘Biovail Merger with Valeant — Fair Value of Consideration Transferred and — Assets Acquired and Liabilities Assumed’’); • a positive foreign currency translation adjustment of $54.6 million to other comprehensive income, mainly due to the impact of the strengthening of the Canadian dollar relative to the U.S. dollar, which increased the reported value of our Canadian dollar-denominated net assets; and • proceeds of $58.4 million from the issuance of common shares on the exercise of stock options. Those factors were partially offset by: • cash dividends declared of $342.0 million; • the net loss of $208.2 million (including $98.0 million of share-based compensation recorded in additional paid-in capital); • the excess of the purchase price of the 5.375% Convertible Notes over their estimated fair value of $131.7 million; • a decrease of $60.1 million related to the repurchase of common shares; and • a decrease of $32.7 million related to the settlement of the written call options on our common shares. 60 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Cash Flows Our primary sources of cash include: the collection of accounts receivable related to product sales; the issuance of long-term debt and borrowings under the Credit Facilities; and proceeds from the sale of non-core assets. Our primary uses of cash include: business development transactions; interest and principal payments; securities repurchases; restructuring activities; salaries and benefits; inventory purchases; research and development spending; sales and marketing activities; capital expenditures; legal costs; litigation and regulatory settlements; and dividend payments. The following table displays cash flow information for each of the last three years: ($ in 000s) Years Ended December 31 Change 2010 2009 2008 2009 to 2010 2008 to 2009 $ $ $ $ % $ % 263,191 77 Net cash provided by operating activities . . . . . . . . . . . . . . . . . . . . . . Net cash provided by (used in) investing activities . . . . . . . . . . . . . . . . 228,939 (742,772) (107,831) 971,711 (131) (634,941) 589 Net cash provided by (used in) financing activities . . . . . . . . . . . . . . . . (213,283) 177,047 (210,311) (390,330) (220) 387,358 (184) 4,021 (177) . . . . . . . . Effect of exchange rate changes on cash and cash equivalents (27) 156,572 (97,706) 360,897 204,325 (2,277) (785) 1,744 (45) 959 Net increase (decrease) in cash and cash equivalents . . . . . . . . . . . . . . Cash and cash equivalents, beginning of year . . . . . . . . . . . . . . . . . . . 279,806 (203,084) (116,094) 482,890 (238) 114,463 433,641 (203,084) (86,990) (64) (116,094) 317,547 75 (27) Cash and cash equivalents, end of year . . . . . . . . . . . . . . . . . . . . . . . 394,269 114,463 317,547 279,806 244 (203,084) (64) Operating Activities Net cash provided by operating activities declined $97.7 million, or 27%, to $263.2 million in 2010, compared with $360.9 million in 2009, primarily due to: • payments related to the Merger-related restructuring charges ($56.4 million) and legal settlement payments related to Biovail legacy litigation matters ($44.5 million); • a decrease related to the receipt of $22.0 million in connection with the auction rate security settlement in 2009 that did not similarly occur in 2010; and • the timing of other receipts and payments in the ordinary course of business. Those factors were partially offset by: • an increase of $30.8 million related to the payments made in 2009 to settle certain Biovail legacy governmental and regulatory matters that did not similarly occur in 2010. Net cash provided by operating activities increased $156.6 million, or 77%, to $360.9 million in 2009, compared with $204.3 million in 2008, primarily due to: • an increase of $93.0 million related to payments made in 2008 to fund the settlement of certain Biovail legacy litigation and regulatory matters that did not similarly occur in 2009; • an increase of $45.1 million related to a contractual payment made to GSK in 2008 in connection with the introduction of generic competition to Wellbutrin XL(cid:4) that did not similarly occur in 2009; • an increase of $22.0 million related to the auction rate security settlement in 2009; and • the timing of other receipts and payments in the ordinary course of business. 61 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Those factors were partially offset by: • a decrease of $30.8 million related to the payments made in 2009 to settle certain Biovail legacy governmental and regulatory matters. Investing Activities Net cash provided by investing activities was $228.9 million in 2010, compared with cash used of $742.8 million in 2009, reflecting an increase of $971.7 million, primarily due to: • an increase of $761.8 million, in the aggregate, related to the Wellbutrin XL(cid:4), tetrabenazine, pimavanserin, fipamezole and GDNF acquisitions in 2009 that did not similarly occur in 2010; and • the $309.0 million of net cash acquired on the acquisition of Valeant. Those factors were partially offset by: • a decrease of $84.5 million, in the aggregate, mainly in respect of the ribavirin, Hamilton brands, istradefylline, AMPAKINE(cid:4) and Staccato(cid:4) loxapine acquisitions in 2010. Net cash used in investing activities increased $634.9 million, or 589%, to $742.8 million in 2009, compared with $107.8 million in 2008, primarily due to: • an increase of $761.8 million, in the aggregate, related to the acquisitions of the various rights to Wellbutrin XL(cid:4), tetrabenazine, pimavanserin, fipamezole and GDNF in 2009. That factor was partially offset by: • a decrease related to an amount of $101.9 million paid in 2008 to acquire Prestwick Pharmaceuticals, Inc. that did not similarly occur in 2009. Financing Activities Net cash used in financing activities was $213.3 million in 2010, compared with cash provided of $177.0 million in 2009, reflecting a decline of $390.3 million, primarily due to: • a decrease of $537.5 million related to the repayments of the Term Loan B Facility, Term Loan A Facility and Cambridge obligation in 2010; • a decrease of $350.0 million related to the issuance of the 5.375% Convertible Notes in 2009 that did not similarly occur in 2010; • a decrease of $254.3 million related to the repurchase of a portion of the 5.375% Convertible Notes (exclusive of the payment of accreted interest reflected as an operating activity); • a decrease of $209.1 million related to the change in dividends paid, mainly due to the payment of the post-Merger special dividend in 2010; and • a decrease of $60.1 million related to the repurchase of common shares in 2010. Those factors were partially offset by: • an increase related to net proceeds of $992.4 million from the issuance of the 2018 Notes in 2010; and • an increase of $57.6 million related to higher proceeds from the issuance of common shares on the exercise of stock options in 2010. 62 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Net cash provided by financing activities was $177.0 million in 2009, compared with cash used of $210.3 million in 2008, reflecting an increase of $387.4 million, primarily due to: • an increase of $350.0 million related to proceeds from the issuance of the 5.375% Convertible Notes in 2009; • an increase of $33.1 million related to lower dividends paid in 2009, reflecting a reduction in our pre-Merger quarterly cash dividend policy to $0.09 per share commencing in May 2009, compared with $0.375 per share in 2008; and • an increase of $29.8 million related to the repurchase of common shares in 2008 that did not similarly occur in 2009. Those factors were partially offset by: • a decrease of $26.3 million related to deferred financing costs on the issuance of the 5.375% Convertible Notes in 2009. Financial Assets (Liabilities) The following table displays our net financial liability position as of December 31, 2010 and 2009: ($ in 000s; Asset (Liability)) Financial assets: As of December 31 2010 $ 2009 $ Change $ % Cash and cash equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Marketable securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394,269 8,166 114,463 21,082 279,806 (12,916) Total financial assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402,435 135,545 266,890 244 (61) 197 Financial liabilities: Term Loan A Facility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2017 Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2020 Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2018 Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5.375% Convertible Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4.0% Convertible Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cambridge obligation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (975,000) (497,589) (695,735) (992,498) (196,763) (220,792) (16,900) — — — — (298,285) — (27,800) (975,000) NM (497,589) NM (695,735) NM (992,498) NM 101,522 (34) (220,792) NM (39) 10,900 Total financial liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (3,595,277) (326,085) (3,269,192) 1,003 Net financial liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (3,192,842) (190,540) (3,002,302) 1,576 NM — Not meaningful Our primary sources of liquidity are our cash flows from operations and issuances of long-term debt securities. We believe that existing cash and cash generated from operations, funds available under the Credit Facilities, supplemented with additional debt issuances as needed, will be sufficient to meet our liquidity needs, based on our current expectations. We have no material commitments for capital expenditures. Our short-term debt maturities consist mainly of $100.0 million outstanding principal amount under the Term A Credit Facility, due in quarterly instalments of $25.0 million. We believe our existing cash and cash generated from operations will be sufficient to cover these short-term debt maturities as they become due. 63 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Part of our business strategy is to expand through strategic acquisitions which may require us to seek additional debt financing, issue additional equity securities or sell assets, as necessary, to finance future acquisitions or for other general corporate purposes. On September 27, 2010, Valeant and certain of its subsidiaries entered into a Credit and Guaranty Agreement (the ‘‘Credit Agreement’’) with a syndicate of lending institutions, which consists of (1) a four-and-one half-year non-amortizing $125.0 million Revolving Credit Facility, which includes a sublimit for the issuance of standby and commercial letters of credit and a sublimit for swing line loans, (2) a five-year amortizing $1.0 billion Term Loan A Facility, and (3) a six-year amortizing $1.625 billion Term Loan B Facility, consisting of a $1.5 billion ‘‘initial draw’’ and a $125.0 million ‘‘delayed draw’’. On September 28, 2010, we and certain of our subsidiaries (other than Valeant and its subsidiaries) entered into Counterpart Agreements or Deeds of Guarantee, as appropriate, to the Credit Agreement, each in substantially the same form. On November 29, 2010, the ‘‘delayed draw’’ under the Term Loan B Facility was terminated. As of December 31, 2010, the ‘‘initial draw’’ under the Term Loan B Facility has been paid in full. We were in compliance with all covenants associated with the Credit Facilities at December 31, 2010. Concurrent with the closing of the Merger, Valeant issued $500.0 million aggregate principal amount of 2017 Notes and $700.0 million aggregate principal amount of 2020 Notes. A portion of the proceeds of the 2017 Notes and 2020 Notes offering was used to pay down $1.0 billion of the Term Loan B Facility. On November 23, 2010, Valeant issued $1.0 billion aggregate principal amount of 2018 Notes. The 2018 Notes were issued at a discount of 99.24% for an effective annual yield of 7.0%. A portion of the proceeds of the 2018 Notes offering was used to repay the remaining $500.0 million owed under the Term Loan B Facility and the balance of the proceeds are expected to be used for general corporate purposes, including acquisitions, debt repayment and securities repurchases. The 2017 Notes, 2020 Notes and 2018 Notes (hereinafter referred to as the ‘‘Notes’’) are senior unsecured obligations of Valeant and are jointly and severally guaranteed on a senior unsecured basis by the Company and each of its subsidiaries (other than Valeant) that is a guarantor under the Credit Facilities (as described above). Certain of the future subsidiaries of Valeant and the Company may be required to guarantee the Notes. The non-guarantor subsidiaries had total assets of $3,411.8 million and total liabilities of $841.2 million as of December 31, 2010, and net revenues of $182.7 million and income from operations of $0.9 million for the year ended December 31, 2010. On February 8, 2011, Valeant issued $650.0 million aggregate principal amount of 2021 Notes. The 2021 Notes are jointly and severally guaranteed on the same senior unsecured basis as the Notes. The net proceeds of the 2021 Notes offering were to be used to finance the acquisitions of PharmaSwiss and the U.S. and Canadian rights to non-ophthalmic topical formulations of Zovirax(cid:4) (as described above under ‘‘Acquisitions — PharmaSwiss and — Zovirax(cid:4)’’) and to pay fees and expenses in connection with these acquisitions and for general corporate purposes. Pending the completion of each of these acquisitions, Valeant deposited $400.0 million of the proceeds of the 2021 Notes offering ($135.0 million of which was released on February 23, 2011 following the completion of the acquisition of the U.S. rights to Zovirax(cid:4)), together with cash in an amount sufficient to pay the special mandatory redemption price for the 2021 Notes, when and if due, into an escrow account. Securities Repurchase Program On November 4, 2010, we announced that our board of directors approved a securities repurchase program, (the ‘‘securities repurchase program’’) pursuant to which we may make purchases of our common shares, Convertible Notes and/or Notes up to an aggregate maximum value of $1.5 billion, subject to any restrictions in the Company’s financing agreements and applicable law. Our board of directors also approved a sub-limit of up to 16.0 million common shares, representing approximately 10% of the Company’s public float (as estimated at 64 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) the commencement of the securities repurchase program), to be purchased for cancellation under a normal course issuer bid through the facilities of the NYSE and Toronto Stock Exchange (‘‘TSX’’). We may initially make purchases under the securities repurchase program of up to 15.0 million common shares through the facilities of the NYSE, in accordance with applicable rules and guidelines. This represented approximately 5% of our issued and outstanding common shares as of November 4, 2010. Following additional filings and related approvals, we may also purchase common shares over the TSX. The program does not require us to repurchase a minimum number of securities, and the program may be modified, suspended or terminated at any time without prior notice. The securities repurchase program will terminate on November 7, 2011 or at such earlier time as we complete our purchases. Under the terms of the Credit Facilities, our purchases under the securities repurchase program are subject to certain monetary thresholds, above which we require the consent of the lenders. In connection with the securities repurchase program, we have, to date, repurchased $137.6 million principal amount of the 5.375% Convertible Notes for consideration of $284.1 million and 2.3 million of our common shares for consideration of $60.1 million. The amount of securities to be purchased and the timing of purchases under the securities repurchase program may be subject to various factors, which may include the price of the securities, general market conditions, corporate and regulatory requirements, alternate investment opportunities and restrictions under our financing agreements. The securities to be repurchased will be funded using our cash resources. On February 24, 2011, we entered into an agreement to repurchase 7.4 million common shares from ValueAct Capital Master Fund, L.P. (‘‘ValueAct’’) for an aggregate purchase price of $275.0 million negotiated at a 5.77% discount over a 20-day trading day average, which was calculated in a similar manner to Valeant’s privately negotiated share repurchase from ValueAct completed in May 2010. The transaction, which is subject to closing conditions, is expected to be consummated on March 17, 2011, or such other time or date as the parties to the purchase agreement may agree. G. Mason Morfit is a partner and a member of the Management Committee of ValueAct Capital. Mr. Morfit joined our board of directors on September 28, 2010, effective with the Merger, and prior thereto served as a member of Valeant’s board of directors since 2007. ValueAct Capital is the general partner and the manager of ValueAct. In connection with the pending $275.0 million share repurchase from ValueAct, we are evaluating debt financing alternatives. Share Repurchase Program On August 6, 2009, we announced that our board of directors had renewed the previous share repurchase program. This program terminated on August 11, 2010. We did not repurchase any of our common shares under the program. OFF-BALANCE SHEET ARRANGEMENTS AND CONTRACTUAL OBLIGATIONS We have no off-balance sheet arrangements that have a material current effect or that are reasonably likely to have a material future effect on our results of operations, financial condition, capital expenditures, liquidity, or capital resources. 65 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) The following table summarizes our contractual obligations as of December 31, 2010, with the exception that long-term debt includes principal and interest payments on the 2021 Notes issued in February 2011: ($ in 000s) Total $ 2011 $ Payments Due by Period 2012 and 2013 2014 and 2015 $ $ Long-term debt obligations(1) . . . . . . . . . . . . . . . . Lease obligations . . . . . . . . . . . . . . . . . . . . . . . . Purchase obligations(2) . . . . . . . . . . . . . . . . . . . . 6,237,645 94,277 60,018 363,541 24,935 38,337 1,049,262 21,153 18,793 1,192,651 12,970 1,976 Thereafter $ 3,632,191 35,219 912 Total contractual obligations . . . . . . . . . . . . . . . . 6,391,940 426,813 1,089,208 1,207,597 3,668,322 (1) Expected interest payments assume repayment of the principal amount of the debt obligations at maturity. (2) Purchase obligations consist of agreements to purchase goods and services that are enforceable and legally binding and include obligations for minimum inventory and capital expenditures, and outsourced information technology, product promotion and clinical research services. The above table does not reflect any contingent milestone or royalty payments in connection with research and development arrangements with third parties. As described above under ‘‘Synergies and Cost Savings — Merger-Related Cost-Rationalization and Integration Initiatives — Research and Development Pipeline Rationalization’’, we have determined not to continue a number of our specialty CNS programs, and have provided notices of termination to, or entered into termination agreements with, the counterparty to each of the related agreements. As a result, we will not be required to make the previously identified contingent milestone or royalty payments under those agreements. As described above under ‘‘Acquisitions — Istradefylline’’, we may be required to make milestone payments of up to $55.0 million in the aggregate in connection with the istradefylline acquisition, contingent on the achievement of specific developmental, regulatory and sales-based milestones. In addition, we may have to make royalty payments based on net commercial sales of products containing istradefylline. In addition, the above table does not reflect assumed contingent milestone payments of Valeant of $412.2 million in the aggregate, including contingent consideration of up to $390.0 million that we may be required to pay related to Valeant’s acquisition of Princeton Pharma Holdings LLC, and its wholly-owned operating subsidiary, Aton Pharma, Inc. (‘‘Aton’’), on May 26, 2010. The Aton contingent consideration consists of future milestones predominantly based upon the achievement of approval and commercial targets for certain pipeline products. Also excluded from the above table is a liability for uncertain tax positions totaling $110.9 million. This liability has been excluded because we cannot currently make a reliable estimate of the period in which the liability will be payable, if ever. OUTSTANDING SHARE DATA Our common shares are listed on the TSX and the NYSE under the ticker symbol ‘‘VRX’’. At February 23, 2011, we had 304,219,307 issued and outstanding common shares and 1,618,095 common shares issuable in connection with the Merger. In addition, we had 11,458,722 stock options and 2,114,246 time-based RSUs that each represent the right of a holder to receive one of the Company’s common shares, and 2,496,427 performance-based RSUs that represent the right of a holder to receive up to 300% of the RSUs granted. A maximum of 5,732,365 common shares could be issued upon vesting of the performance-based RSUs outstanding. 66 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Assuming full share settlement, 14,800,839 common shares are issuable upon the conversion of the 5.375% Convertible Notes (based on a current conversion rate of 69.6943 common shares per $1,000 principal amount of notes, subject to adjustment), and 17,782,891 common shares are issuable upon the conversion of the 4.0% Convertible Notes (based on a current conversion rate of 79.0667 common shares per $1,000 principal amount of notes, subject to adjustment); however, our intent is to settle the Convertible Notes using a net share settlement approach. Under the call option agreements on the 4.0% Convertible Notes assumed in connection with the Merger, we have the right but not the obligation to buy up to 15,813,340 of our common shares from the counterparties to these agreements, and the counterparties have the right but not the obligation to buy from us an identical number of common shares. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK Our business and financial results are affected by fluctuations in world financial markets, including the impacts of foreign currency exchange rate and interest rate movements. We evaluate our exposure to such risks on an ongoing basis, and seek ways to manage these risks to an acceptable level, based on management’s judgment of the appropriate trade-off between risk, opportunity and cost. We use derivative financial instruments from time to time as a risk management tool and not for trading or speculative purposes. Currently, we do not hold any significant amount of market risk sensitive instruments whose value is subject to market price risk. Inflation; Seasonality Historically, our results of operations have not been materially impacted by inflation or seasonality. However, following the Merger, we are subject to price control restriction on our pharmaceutical products in the majority of countries in which we now operate. As a result, our ability to raise prices in a timely fashion in anticipation of inflation may be limited in some markets. Foreign Currency Risk Historically, a majority of our revenue and expense activities and capital expenditures were denominated in U.S. dollars. We also faced foreign currency exposure on the translation of our operations in Canada from Canadian dollars to U.S. dollars. Effective with the Merger, we have additional foreign currency exposure related to the Polish zloty (and other Eastern European currencies), the Mexican peso, the Brazilian real and the Australian dollar from Valeant operations. These operations are subject to risks inherent in conducting business abroad, including price and currency exchange controls and fluctuations in the relative values of currencies. In addition, to the extent that we require, as a source of debt repayment, earnings and cash flows from some of our operations located in foreign countries, we are subject to risk of changes in the value of the U.S. dollar, relative to all other currencies in which we operate, which may materially affect our results of operations. Where possible, we manage foreign currency risk by managing same currency assets in relation to same currency liabilities, and same currency revenues in relation to same currency expenses. In 2010, the repurchase of $126.3 million principal amount of the U.S. dollar-denominated 5.375% Convertible Notes resulted in a foreign exchange gain for Canadian income tax purposes of approximately $10.0 million. The payment of the remaining balance of the 5.375% Convertible Notes will likely result in a foreign exchange gain or loss for Canadian income tax purposes. The amount of this gain or loss will depend on the exchange rate between the U.S. and Canadian dollar at the time the 5.375% Convertible Notes are paid. As of December 31, 2010, the unrealized foreign exchange gain on the translation of the remaining principal amount of the 5.375% Convertible Notes to Canadian dollars for Canadian income tax purposes was approximately $24.0 million. One-half of any realized foreign exchange gain or loss is included in our Canadian taxable income, which results in a corresponding reduction in our available Canadian operating losses and tax credit carryforward balances. However, the payment of the 5.375% Convertible Notes does not result in a 67 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) foreign exchange gain or loss being recognized in our consolidated financial statements, as these statements are prepared in U.S. dollars. Interest Rate Risk We currently do not hold financial instruments for trading or speculative purposes. Our financial assets are not subject to significant interest rate risk due to their short duration. The primary objective of our policy for the investment of temporary cash surpluses is the protection of principal, and accordingly, we generally invest in high quality, liquid money market investments with varying maturities, but typically less than three months. As it is our intent and policy to hold these investments until maturity, we do not have a material exposure to interest rate risk. As of December 31, 2010, we had $2,648.6 million and $975.0 million principal amount of issued fixed rate debt and variable rate debt, respectively, that require U.S. dollar repayment. The estimated fair value of our issued fixed rate debt as of December 31, 2010 was $3,182.7 million. If interest rates were to increase or decrease by 100 basis-points the fair value of our long-term debt would increase or decrease by approximately $166.0 million. We are subject to interest rate risk on our variable rate debt as changes in interest rates could adversely affect earnings and cash flows. A 100 basis-points change in interest rates would have an annualized pre-tax effect of approximately $10.0 million in our consolidated statements of operations and cash flows, based on current outstanding borrowings and effective interest rates on our variable rate debt. While our variable-rate debt may impact earnings and cash flows as interest rates change, it is not subject to changes in fair value. CRITICAL ACCOUNTING POLICIES AND ESTIMATES Critical accounting policies and estimates are those policies and estimates that are most important and material to the preparation of our consolidated financial statements, and which require management’s most subjective and complex judgments due to the need to select policies from among alternatives available, and to make estimates about matters that are inherently uncertain. We base our estimates on historical experience and other factors that we believe to be reasonable under the circumstances. On an ongoing basis, we review our estimates to ensure that these estimates appropriately reflect changes in our business and new information as it becomes available. If historical experience and other factors we use to make these estimates do not reasonably reflect future activity, our results of operations and financial condition could be materially impacted. Revenue Recognition We recognize product sales revenue when title has transferred to the customer and the customer has assumed the risks and rewards of ownership. Revenue from product sales is recognized net of provisions for estimated cash discounts, allowances, returns, rebates, and chargebacks, as well as distribution fees paid to certain of our wholesale customers. We establish these provisions concurrently with the recognition of product sales revenue. Under certain product manufacturing and supply agreements, we rely on estimates for future returns, rebates and chargebacks made by our commercialization counterparties. We make adjustments as needed to state these estimates on a basis consistent with our revenue recognition policy and our methodology for estimating returns, rebates, and chargebacks related to our own direct product sales. We continually monitor our product sales provisions and evaluate the estimates used as additional information becomes available. We make adjustments to these provisions periodically to reflect new facts and circumstances that may indicate that historical experience may not be indicative of current and/or future results. We are required to make subjective judgments based primarily on our evaluation of current market conditions and trade inventory levels related to our products. This evaluation may result in an increase or decrease in the experience rate that is applied to current and future sales, or an adjustment related to past sales, or both. 68 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Continuity of Product Sales Provisions The following table presents the activity and ending balances for our product sales provisions for each of the last three years. Discounts and Allowances Returns Rebates Chargebacks Distribution Fees ($ in 000s) $ $ $ $ $ Balance, January 1, 2008 . . . . . . . . . . . . Current year provision . . . . . . . . . . . . . . Prior year provision . . . . . . . . . . . . . . . . Payments or credits . . . . . . . . . . . . . . . . 1,041 8,398 — (8,600) 19,362 19,919 (4,599) (9,590) 7,180 15,226 (1,297) (15,238) 783 9,222 — (9,603) 4,326 10,670 — (11,278) Total $ 32,692 63,435 (5,896) (54,309) Balance, December 31, 2008 . . . . . . . . . 839 25,092 5,871 402 3,718 35,922 Current year provision . . . . . . . . . . . . . . Prior year provision . . . . . . . . . . . . . . . . Payments or credits . . . . . . . . . . . . . . . . 13,390 — (12,547) 16,498 3,767 (20,773) 31,555 6,852 (23,344) 16,795 — (14,901) 16,894 — (15,154) 95,132 10,619 (86,719) Balance, December 31, 2009 . . . . . . . . . 1,682 24,584 20,934 2,296 5,458 54,954 Acquisition of Valeant . . . . . . . . . . . . . . Current year provision . . . . . . . . . . . . . . Prior year provision . . . . . . . . . . . . . . . . Payments or credits . . . . . . . . . . . . . . . . 3,974 24,286 — (22,293) 81,441 26,377 (3,430) (18,330) 59,914 86,527 1,236 (88,907) 8,932 35,428 — (36,415) 7,149 24,345 — (22,851) 161,410 196,963 (2,194) (188,796) Balance, December 31, 2010 . . . . . . . . . 7,649 110,642 79,704 10,241 14,101 222,337 Use of Information from External Sources In the U.S., we use information from external sources to estimate our product sales provisions. We have data sharing agreements with the three largest wholesalers in the U.S. Where we do not have data sharing agreements, we use third-party data to estimate the level of product inventories and product demand at wholesalers and retail pharmacies. Third-party data with respect to prescription demand and inventory levels are subject to the inherent limitations of estimates that rely on information from external sources, as this information may itself rely on certain estimates and reflect other limitations. Our inventory levels in the wholesale distribution channel do not vary substantially, as our distribution agreements with the three largest wholesalers in the U.S. limit the aggregate amount of inventory they can own to between 1⁄2 and 11⁄2 months of supply of our products. The inventory data from these wholesalers is provided to us in the aggregate rather than by specific lot number, which is the level of detail that would be required to determine the original sale date and remaining shelf life of the inventory. Some European countries base their rebates on the government’s unbudgeted pharmaceutical spending and we use an estimated allocation factor against our actual invoiced sales to project the expected level of reimbursement. We obtain third-party information that helps us to monitor the adequacy of these accruals. If our estimates are not indicative of actual unbudgeted spending, our results could be materially affected. Cash Discounts and Allowances We offer cash discounts for prompt payment and allowances for volume purchases to customers. Provisions for cash discounts are estimated at the time of sale and recorded as direct reductions to accounts receivable and revenue. Provisions for allowances are recorded in accrued liabilities. We estimate provisions for cash discounts and allowances based on contractual sales terms with customers, an analysis of unpaid invoices, and historical payment experience. Estimated cash discounts and allowances have historically been predictable and less 69 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) subjective, due to the limited number of assumptions involved, the consistency of historical experience, and the fact that we generally settle these amounts within one month of incurring the liability. Returns Consistent with industry practice, we generally allow customers to return product within a specified period before and after its expiration date. Our product returns provision is estimated based on historical sales and return rates over the period during which customers have a right of return. We utilize the following information to estimate our provision for returns: • historical return and exchange levels; • external data with respect to inventory levels in the wholesale distribution channel; • external data with respect to prescription demand for our products; • remaining shelf lives of our products at the date of sale; and • estimated returns liability to be processed by year of sale based on an analysis of lot information related to actual historical returns. In determining our estimates for returns, we are required to make certain assumptions regarding the timing of the introduction of new products and the potential of these products to capture market share. In addition, we make certain assumptions with respect to the extent and pattern of decline associated with generic competition. To make these assessments, we utilize market data for similar products as analogs for our estimates. We use our best judgment to formulate these assumptions based on past experience and information available to us at the time. We continually reassess and make the appropriate changes to our estimates and assumptions as new information becomes available to us. Our estimate for returns may be impacted by a number of factors, but the principal factor relates to the level of inventory in the distribution channel. When we are aware of an increase in the level of inventory of our products in the distribution channel, we consider the reasons for the increase to determine if the increase may be temporary or other-than-temporary. Increases in inventory levels assessed as temporary will not result in an adjustment to our provision for returns. Other-than-temporary increases in inventory levels, however, may be an indication that future product returns could be higher than originally anticipated, and, as a result, we may need to adjust our estimate for returns. Some of the factors that may suggest that an increase in inventory levels will be temporary include: • recently implemented or announced price increases for our products; • new product launches or expanded indications for our existing products; and • timing of purchases by our wholesale customers. Conversely, factors that may suggest that an increase in inventory levels will be other-than-temporary include: • declining sales trends based on prescription demand; • introduction of new products or generic competition; • increasing price competition from generic competitors; and • recent changes to the U.S. National Drug Codes (‘‘NDC’’) of our products, which could result in a period of higher returns related to products with the old NDC, as our U.S. customers generally permit only one NDC per product for identification and tracking within their inventory systems. Our adjustments to actual in 2010, 2009 and 2008 were not material to our revenues or earnings. 70 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) Rebates and Chargebacks We are subject to rebates on sales made under governmental and managed-care pricing programs in the U.S. The largest of these rebates is associated with sales covered by Medicaid. We participate in state government-managed Medicaid programs, as well as certain other qualifying federal and state government programs whereby discounts and rebates are provided to participating government entities. Medicaid rebates are typically billed up to 180 days after the product is shipped, but can be as much as 270 days after the quarter in which the product is dispensed to the Medicaid participant. As a result, our Medicaid rebate provision includes an estimate of outstanding claims for end-customer sales that occurred but for which the related claim has not been billed, and an estimate for future claims that will be made when inventory in the distribution channel is sold through to plan participants. Our calculation also requires other estimates, such as estimates of sales mix, to determine which sales are subject to rebates and the amount of such rebates. Periodically, we adjust the Medicaid rebate provision based on actual claims paid. Due to the delay in billing, adjustments to actual claims paid may incorporate revisions of that provision for several periods. Chargebacks relate to our contractual agreements to sell products to group purchasing organizations and other indirect customers at contractual prices that are lower than the list prices we charge wholesalers. When these group purchasing organizations or other indirect customers purchase our products through wholesalers at these reduced prices, the wholesaler charges us for the difference between the prices they paid us and the prices at which they sold the products to the indirect customers. In estimating our provisions for rebates and chargebacks, we consider relevant statutes with respect to governmental pricing programs and contractual sales terms with managed-care providers and group purchasing organizations. We estimate the amount of our product sales subject to these programs based on historical utilization levels. Changes in the level of utilization of our products through private or public benefit plans and group purchasing organizations will affect the amount of rebates and chargebacks that we are obligated to pay. We continually update these factors based on new contractual or statutory requirements, and any significant changes in sales trends that may impact the percentage of our products subject to rebates or chargebacks. The amount of rebates and chargebacks has become more significant as a result of a combination of deeper discounts due to the price increases we implemented in each of the last three years and increased Medicaid utilization due to existing economic conditions in the U.S. Our estimate for rebates and chargebacks may be impacted by a number of factors, but the principal factor relates to the level of inventory in the distribution channel. We do not process or track actual rebate payments or credits by period in which the original sale was made, as the necessary lot information is not required to be provided to us by the private or public benefit providers. Accordingly, we generally assume that adjustments made to rebate provisions relate to sales made in the prior years due to the delay in billing. However, we assume that adjustments made to chargebacks are generally related to sales made in the current year, as we settle these amounts within a few months of original sale. Our adjustments to actual in 2010 and 2008 were not material to our revenues or earnings. We recorded an adjustment of $6.9 million in 2009 to increase the provision for rebates as a result of higher than anticipated Medicaid utilization, due to the economic condition in the U.S. and the related increase in the number of patients in these governmental programs. Acquisitions We account for acquired businesses using the acquisition method of accounting, which requires that assets acquired and liabilities assumed be recorded at fair value, with limited exceptions. Any excess of the purchase price over the fair value of the net assets acquired is recorded as goodwill. Amounts allocated to acquired IPR&D are recognized at fair value and initially characterized as indefinite-lived intangible assets, irrespective of whether the acquired IPR&D has an alternative future use. If the acquired net assets do not constitute a business, the transaction is accounted for as an asset acquisition and no goodwill is recognized. In an asset acquisition, acquired IPR&D with no alternative future use is charged to expense at the acquisition date. 71 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) The judgments made in determining the estimated fair value assigned to each class of asset acquired and liability assumed can materially impact our results of operations. As a result, we typically engage independent valuation specialists to perform valuations of the net assets acquired. There are several methods that can be used to determine fair value. For intangible assets, including IPR&D, we typically use an income approach. This approach starts with a forecast of the net cash flows expected to be generated by the asset over its estimated useful life. These cash flows are then adjusted to present value by applying an appropriate discount rate that reflects the risk factors associated with the cash flow streams. Some of the more significant estimates and assumptions inherent in the income approach include: • the amount and timing of projected future cash flows, adjusted for the probability of technical and marketing success; • the amount and timing of projected costs to develop IPR&D into commercially viable products; • the discount rate selected to measure the risks inherent in the future cash flows; and • an assessment of the asset’s life cycle and the competitive trends impacting the asset, including consideration of any technical, legal, regulatory, or economic barriers to entry. We believe the fair values assigned to the assets acquired and liabilities assumed are based on reasonable assumptions, however, these assumptions may be incomplete or inaccurate, and unanticipated events and circumstances may occur. Determining the useful life of an intangible asset also requires judgment, as different types of intangible assets will have different useful lives and certain assets may even be considered to have indefinite useful lives. Useful life is the period over which the intangible asset is expected to contribute directly or indirectly to our future cash flows. We determine the useful lives of intangible assets based on a number of factors, such as legal, regulatory, or contractual provisions that may limit the useful life, and the effects of obsolescence, anticipated demand, existence or absence of competition, and other economic factors on useful life. Intangible Assets We evaluate amortizable intangible assets acquired through asset acquisitions or business combinations for impairment annually, and more frequently if events or changes in circumstances indicate that the carrying amounts of these assets may not be recoverable. Our evaluation is based on an assessment of potential indicators of impairment, such as: • an adverse change in legal factors or in the business climate that could affect the value of an asset. For example, a successful challenge of our patent rights resulting in earlier than expected generic competition; • an adverse change in the extent or manner in which an asset is used or is expected to be used. For example, a decision not to pursue a product line-extension strategy to enhance an existing product due to changes in market conditions and/or technological advances; or • current or forecasted operating or cash flow losses that demonstrate continuing losses associated with the use of an asset. For example, the introduction of a competing product that results in a significant loss of market share. Impairment exists when the carrying amount of an amortizable intangible asset is not recoverable and its carrying value exceeds its estimated fair value. A discounted cash flow analysis is typically used to determine fair value using estimates and assumptions that market participants would apply. Some of the estimates and assumptions inherent in a discounted cash flow model include the amount and timing of the projected future cash flows, and the discount rate used to reflect the risks inherent in the future cash flows. A change in any of these estimates and assumptions could produce a different fair value, which could have a material impact on our results of operations. In addition, an intangible asset’s expected useful life can increase estimation risk, as longer-lived assets necessarily require longer-term cash flow forecasts, which for some of our intangible assets 72 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) can be up to 25 years. In connection with an impairment evaluation, we also reassess the remaining useful life of the intangible asset and modify it, as appropriate. Indefinite-lived intangible assets, including IPR&D, are tested for impairment annually, or more frequently if events or changes in circumstances between annual tests indicate that the asset may be impaired. Impairment losses on indefinite-lived intangible assets are recognized based solely on a comparison of their fair value to carrying value, without consideration of any recoverability test. Goodwill Goodwill represents the excess of the purchase price of acquired businesses over the estimated fair value of the identifiable net assets acquired. Goodwill is not amortized but is tested for impairment at least annually at the reporting unit level. A reporting unit is the same as, or one level below, an operating segment. The fair value of a reporting unit refers to the price that would be received to sell the unit as a whole in an orderly transaction between market participants. Prior to the Merger, we had one operating segment and one reporting unit. Accordingly, in fiscal years 2010 and 2009, goodwill existing prior to the Merger was tested for impairment by comparing our pre-Merger market capitalization, based on the quoted market price of our underlying common shares, to the carrying value of our consolidated net assets. On that basis, there was no indication of goodwill impairment. Effective with the Merger, we operate in the following business segments: U.S. Neurology and Other; U.S. Dermatology; Canada and Australia; Branded Generics — Europe; and Branded Generics — Latin America. Each of the U.S. Neurology and Other, U.S. Dermatology and Branded Generics — Europe segments consist of one reporting unit. The Canada and Australia segment consists of two geographical reporting units. Similarly, the Branded Generics — Latin America segment consists of two reporting units based on geography, namely Mexico and Brazil. The Company has provisionally allocated goodwill to the seven reporting units. Goodwill recognized as a result of the Merger will be tested for impairment commencing in 2011. An interim goodwill impairment test in advance of the annual impairment assessment may be required if events occur that indicate an impairment might be present. For example, a substantial decline in our market capitalization may signal that an interim impairment test is needed. Accordingly, we monitor changes in our share price between annual impairment tests to ensure that our market capitalization continues to exceed the carrying value of our consolidated net assets. We consider a decline in our share price that corresponds to an overall deterioration in stock market conditions to be less of an indicator of goodwill impairment than a unilateral decline in our share price reflecting adverse changes in our underlying operating performance, cash flows, financial condition, and/or liquidity. In the event that our market capitalization does decline below its book value, we would consider the length and severity of the decline and the reason for the decline when assessing whether potential goodwill impairment exists. We believe that short-term fluctuations in share prices may not necessarily reflect underlying values. For example, a decline in share price due to the following reasons may not be indicative of an actual decline in the aggregate fair value at the reporting unit level: • the decline is linked to external events or conditions, such as broad market reaction to circumstances associated with one (or a few) pharmaceutical companies, which could cause temporary market declines for other companies in the same sector; or • the decline is associated with unusual market activity, such as a spike in short selling activity, which may have a temporary impact on a company’s market capitalization but not reflect its underlying fair value. However, if a decline in our market capitalization below book value persists for an extended period of time, we would likely consider the decline to be indicative of a decline in the aggregate fair value at the reporting unit level. Contingencies In the normal course of business, we are subject to loss contingencies, such as claims and assessments arising from litigation and other legal proceedings; contractual indemnities; product and environmental 73 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) liabilities; and tax matters. We are required to accrue for such loss contingencies if it is probable that the outcome will be unfavourable and if the amount of the loss can be reasonably estimated. We are often unable to develop a best estimate of loss, in which case the minimum amount of loss, which could be zero, is recorded. We evaluate our exposure to loss based on the progress of each contingency, experience in similar contingencies, and consultation with internal and external legal counsel. We re-evaluate all contingencies as additional information becomes available. Given the uncertainties inherent in complex litigation and other contingencies, these evaluations can involve significant judgment about future events. The ultimate outcome of any litigation or other contingency may be material to our results of operations, financial condition, and cash flows. For a discussion of our current legal proceedings, see note 24 to the 2010 Financial Statements. Income Taxes We have operations in various countries that have differing tax laws and rates. Our tax structure is supported by current domestic tax laws in the countries in which we operate and the application of tax treaties between the various countries in which we operate. Our income tax reporting is subject to audit by domestic and foreign tax authorities. Our effective tax rate may change from year to year based on changes in the mix of activities and income allocated or earned among the different jurisdictions in which we operate, changes in tax laws in these jurisdictions, changes in tax treaties between various countries in which we operate, changes in our eligibility for benefits under those tax treaties, and changes in the estimated values of deferred tax assets and liabilities. Such changes could result in an increase in the effective tax rate on all or a portion of our income and/or any of our subsidiaries. Our provision for income taxes is based on a number of estimates and assumptions made by management. Our consolidated income tax rate is affected by the amount of income earned in our various operating jurisdictions, the availability of benefits under tax treaties, and the rates of taxes payable in respect of that income. We enter into many transactions and arrangements in the ordinary course of business in which the tax treatment is not entirely certain. We must therefore make estimates and judgments based on our knowledge and understanding of applicable tax laws and tax treaties, and the application of those tax laws and tax treaties to our business, in determining our consolidated tax provision. For example, certain countries could seek to tax a greater share of income than has been provided for by us. The final outcome of any audits by taxation authorities may differ from the estimates and assumptions we have used in determining our consolidated income tax provisions and accruals. This could result in a material effect on our consolidated income tax provision, results of operations, and financial condition for the period in which such determinations are made. Our income tax returns are subject to audit in various jurisdictions. Existing and future audits by, or other disputes with, tax authorities may not be resolved favourably for us and could have a material adverse effect on our reported effective tax rate and after-tax cash flows. We record liabilities for uncertain tax positions, which involves significant management judgment. New laws and new interpretations of laws and rulings by tax authorities may affect the liability for uncertain tax positions. Due to the subjectivity and complex nature of the underlying issues, actual payments or assessments may differ from our estimates. To the extent that our estimates differ from amounts eventually assessed and paid our income and cash flows may be materially and adversely affected. We assess whether it is more likely than not that we will realize the tax benefits associated with our deferred tax assets and establish a valuation allowance for assets that are not expected to result in a realized tax benefit. A significant amount of judgment is used in this process, including preparation of forecasts of future taxable income and evaluation of tax planning initiatives. If we revise these forecasts or determine that certain planning events will not occur, an adjustment to the valuation allowance will be made to tax expense in the period such determination is made. Share-Based Compensation We recognize employee share-based compensation, including grants of stock options and RSUs, at estimated fair value. As there is no market for trading our employee stock options, we use the Black-Scholes 74 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) option-pricing model to calculate stock option fair values, which requires certain assumptions related to the expected life of the stock option, future stock price volatility, risk-free interest rate, and dividend yield. The expected life of the stock option is based on historical exercise and forfeiture patterns. Future stock price volatility is based on historical volatility of our common shares over the expected life of the stock option. The risk-free interest rate is based on the rate at the time of grant for U.S. or Canadian government bonds with a remaining term equal to the expected life of the stock option. Dividend yield is based on the stock option’s exercise price and expected annual dividend rate at the time of grant. Changes to any of these assumptions, or the use of a different option-pricing model, such as the lattice model, could produce a different fair value for share-based compensation expense, which could have a material impact on our results of operations. We determine the fair value of each RSU granted based on the trading price of our common shares on the date of grant, unless the vesting of the RSU is conditional on the attainment of any applicable performance goals, in which case we use a Monte Carlo simulation model. The Monte Carlo simulation model utilizes multiple input variables to estimate the probability that the performance condition will be achieved. Changes to any of these inputs could materially affect the measurement of the fair value of the performance-based RSUs. NEW ACCOUNTING STANDARDS Adoption of New Accounting Standards Information regarding the adoption of new accounting guidance is contained in note 2 to the 2010 Financial Statements. Recently Issued Accounting Standards, Not Adopted as of December 31, 2010 Effective January 1, 2011, we have adopted the provisions of the following new accounting standards: • Guidance on the recognition and classification of fees imposed on pharmaceutical manufacturers under the U.S. Patient Protection and Affordable Care Act. • Guidance recognizing the milestone method of revenue recognition as a valid application of the proportional performance model when applied to research and development arrangements. • Amendments to the recognition and measurement guidance for multiple-element revenue arrangements. We are currently evaluating the effect that the adoption of these standards will have on our financial condition and results of operations. International Financial Reporting Standards International Financial Reporting Standards (‘‘IFRS’’) will replace Canadian standards and interpretations as Canadian GAAP effective January 1, 2011. Effective January 1, 2011, National Instrument 52-107, ‘‘Acceptable Accounting Principles and Auditing Standards’’, continues to allow Canadian public companies who are also SEC issuers the option to use U.S. GAAP. Accordingly, we currently intend to continue our practice of following U.S. GAAP in financial statements filed with the Canadian Securities Administrators (‘‘CSA’’) and the SEC. We believe that U.S. GAAP financial statements afford better comparability with our U.S.-based industry peers. FORWARD-LOOKING STATEMENTS Caution regarding forward-looking information and statements and ‘‘Safe-Harbor’’ statements under the U.S. Private Securities Litigation Reform Act of 1995: To the extent any statements made in this MD&A contain information that is not historical, these statements are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and may be forward-looking information within the meaning defined under applicable Canadian securities legislation (collectively, ‘‘forward- looking statements’’). These forward looking statements relate to, among other things: the expected benefits of 75 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) the Merger, such as cost savings, operating synergies and growth potential of the Company; business plans and prospects, prospective products or product approvals, future performance or results of current and anticipated products; the impact of healthcare reform; exposure to foreign currency exchange rate changes and interest rate changes; the outcome of contingencies, such as certain litigation and regulatory proceedings; general market conditions; and our expectations regarding our financial performance, including revenues, expenses, gross margins, liquidity and income taxes. Forward-looking statements can generally be identified by the use of words such as ‘‘believe’’, ‘‘anticipate’’, ‘‘expect’’, ‘‘intend’’, ‘‘estimate’’, ‘‘plan’’, ‘‘continue’’, ‘‘will’’, ‘‘may’’, ‘‘could’’, ‘‘would’’, ‘‘target’’, ‘‘potential’’ and other similar expressions. In addition, any statements that refer to expectations, projections or other characterizations of future events or circumstances are forward-looking statements. These forward-looking statements may not be appropriate for other purposes. Although we have indicated above certain of these statements set out herein, all of the statements in this MD&A that contain forward-looking statements are qualified by these cautionary statements. Although we believe that the expectations reflected in such forward- looking statements are reasonable, such statements involve risks and uncertainties, and undue reliance should not be placed on such statements. Certain material factors or assumptions are applied in making forward- looking statements, including, but not limited to, factors and assumptions regarding the items outlined above. Actual results may differ materially from those expressed or implied in such statements. Important factors that could cause actual results to differ materially from these expectations include, among other things, the following: • our ability to compete against companies that are larger and have greater financial, technical and human resources than we do, as well as other competitive factors, such as technological advances achieved, patents obtained and new products introduced by our competitors; • factors relating to the integration of the businesses of Valeant and Biovail, including: our ability to integrate the business in the expected time frame, including the integration of the research and development, manufacturing, distribution, sales, marketing and promotion activities and financial and information technology systems of Valeant and Biovail; the difficulties of integrating personnel while maintaining focus on producing and delivering consistent, high quality products and retaining existing customers and attracting new customers; and the realization of the anticipated benefits, including cost savings, from such integration; • the challenges and difficulties associated with managing a larger, more complex, combined business; • our eligibility for benefits under tax treaties and the continued availability of low effective tax rates for the business profits of our significant operating subsidiary in Barbados; • our ability to retain, motivate and recruit executives and other key employees; • our future cash flows, our ability to service and repay our existing debt, and our ability to raise additional funds, if needed, in light of our current and projected levels of operations, acquisition activity and general economic conditions; • our ability to identify, acquire and integrate acquisition targets and to secure and maintain third-party research, development, manufacturing, marketing or distribution arrangements; • the risks associated with the international scope of our operations; • the impacts of the Patient Protection and Affordable Care Act in the U.S. and other legislative and regulatory reforms in the countries in which we operate; • the uncertainties associated with the acquisition and launch of new products, including, but not limited to, the acceptance and demand for new pharmaceutical products, and the impact of competitive products and pricing; • the difficulty in predicting the expense, timing and outcome within our legal and regulatory environment, including, but not limited to, the FDA, the Canadian Therapeutic Products Directorate and European regulatory approvals, legal and regulatory proceedings and settlements thereof, the protection afforded 76 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) by our patents and other intellectual and proprietary property, successful challenges to our generic products and infringement or alleged infringement of the intellectual property of others; • the success of preclinical and clinical trials for our drug development pipeline or delays in clinical trials that adversely impact the timely commercialization of our pipeline products; • the results of continuing safety and efficacy studies by industry and government agencies; • the risk that our products could cause, or be alleged to cause, personal injury, leading to withdrawals of products from the market; • our ability to obtain components, raw materials or other products supplied by third-parties; • the outcome of legal proceedings, investigations and regulatory proceedings; • economic factors over which the Company has no control, including changes in inflation, interest rates, foreign currency rates, and the potential effect of such factors on revenues, expenses and resulting margins; • the disruption of delivery of our products and the routine flow of manufactured goods across the U.S. border; and • other risks detailed from time to time in our filings with the SEC and the CSA, as well as our ability to anticipate and manage the risks associated with the foregoing. Additional information about these factors and about the material factors or assumptions underlying such forward-looking statements may be found elsewhere in this MD&A, as well as under Item 1A. ‘‘Risk Factors’’ of the 2010 Form 10-K, and in our other filings with the SEC and CSA. We caution that the foregoing list of important factors that may affect future results is not exhaustive. When relying on our forward-looking statements to make decisions with respect to the Company, investors and others should carefully consider the foregoing factors and other uncertainties and potential events. These forward-looking statements speak only as of the date made. MANAGEMENT’S REPORT ON DISCLOSURE CONTROLS AND PROCEDURES AND INTERNAL CONTROL OVER FINANCIAL REPORTING Disclosure Controls and Procedures We performed an evaluation of the effectiveness of our disclosure controls and procedures that are designed to ensure that the material financial and non-financial information required to be disclosed on reports and filed or submitted with the SEC is recorded, processed, summarized, and reported in a timely manner. Based on our evaluation, our management, including the Chief Executive Officer (‘‘CEO’’) and Chief Financial Officer (‘‘CFO’’), has concluded that our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) of the Securities Exchange Act of 1934) as of December 31, 2010 are effective. Notwithstanding the foregoing, there can be no assurance that our disclosure controls and procedures will detect or uncover all failures of persons within the Company to disclose material information otherwise required to be set forth in our reports. Internal Controls Over Financial Reporting Our management is responsible for establishing and maintaining adequate internal control over financial reporting as defined in Rules 13a-15(f) and 15d-15(f) under the Securities Exchange Act of 1934. Our internal accounting controls systems are designed to provide reasonable assurance that assets are safeguarded, that transactions are executed in accordance with management’s authorization and are properly recorded, and that accounting records are adequate for preparation of financial statements in accordance with U.S. GAAP and other financial information. Under the supervision and with the participation of management, including our CEO and CFO, we conducted an evaluation of the effectiveness of our internal control over financial reporting based on the 77 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (Continued) framework in Internal Control — Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission. Based on its evaluation under this framework, management concluded that our internal controls over financial reporting were effective as of December 31, 2010. The scope of management’s assessment of the effectiveness of internal control over financial reporting includes all of the Company’s consolidated operations except for the operations of Valeant, which represented 23% of the Company’s consolidated revenues for the year ended December 31, 2010, and assets associated with Valeant’s operations (excluding intangible assets, goodwill and other fair value adjustments arising from the acquisition accounting for Valeant) represented 11% of the Company’s consolidated total assets as of December 31, 2010. The effectiveness of the Company’s internal controls over financial reporting as of December 31, 2010 has been audited by Ernst & Young LLP, as stated in their report on page F-4 of the 2010 Form 10-K. Changes in Internal Control Over Financial Reporting There were no changes in our internal controls over financial reporting identified in connection with the evaluation thereof by our management, including the CEO and CFO, during the quarter ended December 31, 2010 that have materially affected, or are reasonably likely to materially affect, our internal controls over financial reporting. 78 Item 7A. Quantitative and Qualitative Disclosures About Market Risk Information relating to quantitative and qualitative disclosures about market risk is detailed in Item 7. ‘‘Management’s Discussion and Analysis of Financial Condition and Results of Operations’’ and is incorporated herein by reference. Item 8. Financial Statements and Supplementary Data The information required by this Item is contained in the financial statements set forth in Item 15. ‘‘Consolidated Financial Statements and ‘‘Exhibits, Financial Statement Schedules’’ under the caption Supplementary Data’’ as part of this Form 10-K and is incorporated herein by reference. Item 9. Changes in and Disagreements with Accountants on Accounting and Financial Disclosure Prior to the Merger, Ernst & Young LLP (‘‘E&Y’’) audited Biovail’s historical financial statements and PricewaterhouseCoopers LLP (‘‘PwC’’) audited Valeant’s historical financial statements. On November 19, 2010, we notified E&Y and PwC that our Finance and Audit Committee (the ‘‘Audit Committee’’) determined to recommend to our board of directors that, at the Company’s annual general meeting of shareholders in 2011, our board of directors recommend that shareholders appoint PwC as the Company’s independent registered public accountant for the year ending December 31, 2011. E&Y has continued to serve as our independent registered public accountant engaged to audit our consolidated financial statements as of and for the year ending December 31, 2010. The audit report of E&Y on the consolidated financial statements of Biovail as of and for each of the two fiscal years ended December 31, 2009 and 2008 did not contain any adverse opinion or disclaimer of opinion, nor was it qualified or modified as to uncertainty, audit scope, or accounting principles. The audit report of E&Y on our consolidated financial statements as of and for the year ending December 31, 2010 does not contain any adverse opinion or disclaimer of opinion, nor is it qualified or modified as to uncertainty, audit scope or accounting principle. During Biovail’s fiscal years ended December 31, 2009 and 2008, and in the subsequent interim period from January 1, 2010 through November 19, 2010, the date E&Y was notified of the Audit Committee’s decision to recommend that PwC be appointed as the Company’s independent registered public accountant at the next annual general meeting of shareholders, and in the subsequent period following such date, (i) there were no disagreements with E&Y on any matter of accounting principles or practices, financial statement disclosure, or auditing scope or procedure, which disagreements, if not resolved to E&Y’s satisfaction, would have caused E&Y to make reference to the subject matter of the disagreement in connection with its report, and (ii) there were no reportable events of the type described in Item 304(a)(1)(v) of Regulation S-K. Item 9A. Controls and Procedures The Company’s management, with the participation of the Company’s Chief Executive Officer and Chief Financial Officer, has evaluated the effectiveness of the Company’s disclosure controls and procedures (as such term is defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended (the ‘‘Exchange Act’’)) as of the end of the period covered by this annual report (the ‘‘Evaluation Date’’). Based on such evaluation, the Company’s Chief Executive Officer and Chief Financial Officer have concluded that, as of the Evaluation Date, the Company’s disclosure controls and procedures are effective. Internal Control Over Financial Reporting (a) Management’s Annual Report on Internal Control Over Financial Reporting. Management’s Annual Report on Internal Control Over Financial Reporting is incorporated herein by reference from Part II, Item 8 of this report. (b) Report of the Registered Public Accounting Firm. The Report of the Registered Public Accounting Firm on the Company’s internal control over financial reporting is incorporated herein by reference from Part II, Item 8 of this report. (c) Changes in Internal Control Over Financial Reporting. There have not been any changes in the Company’s internal control over financial reporting (as such term is defined in Rules 13a-15(f) 79 and 15d-15(f) under the Exchange Act) during the last fiscal quarter of 2010 that have materially affected, or are reasonably likely to materially affect, the Company’s internal control over financial reporting. Item 9B. Other Information None. 80 Item 10. Directors, Executive Officers and Corporate Governance PART III Information required under this Item is incorporated herein by reference from information included in the 2011 Proxy Statement. The Board of Directors has adopted a Code of Ethics that applies to our Chief Executive Officer, Chief Financial Officer, the principal accounting officer, controller, and all vice presidents and above in the finance department of the Company worldwide. A copy of the Code of Ethics can be found on our website at: www.valeant.com. We intend to satisfy the SEC disclosure requirements regarding amendments to, or waivers from, any provisions of our Code of Ethics on our website. Item 11. Executive Compensation Information required under this Item relating to executive compensation is incorporated herein by reference from information included in the 2011 Proxy Statement. Item 12. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters Information required under this Item relating to securities authorized for issuance under equity compensation plans and to security ownership of certain beneficial owners and management is incorporated herein by reference from information included in the 2011 Proxy Statement. Item 13. Certain Relationships and Related Transactions, and Director Independence Information required under this Item relating to certain relationships and transactions with related parties and about director independence is incorporated herein by reference from information included in the 2011 Proxy Statement. Item 14. Principal Accounting Fees and Services Information required under this Item relating to the fees for professional services rendered by our independent auditors in 2010 and 2009 is incorporated herein by reference from information included in the 2011 Proxy Statement. 81 Item 15. Exhibits, Financial Statement Schedules Documents filed as a part of the report: PART IV (1) The consolidated financial statements required to be filed in the Annual Report on Form 10-K are listed on page F-1 hereof. (2) Schedule II — Valuation and Qualifying Accounts. SCHEDULE II — VALUATION AND QUALIFYING ACCOUNTS (All dollar amounts expressed in thousands of U.S. dollars) Balance at Beginning of Year Charged to Costs and Expenses Charged to Other Accounts Deductions Balance at End of Year Year ended December 31, 2010 Allowance for doubtful accounts . . . . . . . . . . . . . . Allowance for inventory obsolescence . . . . . . . . . . . Year ended December 31, 2009 Allowance for doubtful accounts . . . . . . . . . . . . . . Allowance for inventory obsolescence . . . . . . . . . . . Year ended December 31, 2008 Allowance for doubtful accounts . . . . . . . . . . . . . . Allowance for inventory obsolescence . . . . . . . . . . . $ 2,437 $ 8,560 $ 531 $6,356 $ 7,138 $18,821 $(3,414) $(5,672) $ 6,692 $28,065 $ 1,179 $10,343 $1,304 $7,370 $ — $ — $ (46) $(9,153) $ 2,437 $ 8,560 $ 1,217 $13,792 $ (23) $4,284 $ — $ — $ (15) $(7,733) $ 1,179 $10,343 (3) Exhibits 82 Exhibit Number Exhibit Description EXHIBIT INDEX 2.1 Agreement and Plan of Merger, dated as of September 16, 2008, by and among Biovail Americas Corp., Prestwick Holdings, Inc., Prestwick Pharmaceuticals, Inc. and Sofinnova Management V 2005, LLC and Edgar G. Engleman, M.D., as the Stockholder Representatives, originally filed as Exhibit 2.1 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein.**†† 2.2 Asset Purchase Agreement, dated as of May 5, 2009, by and between Biovail Laboratories International SRL and SmithKline Beecham Corporation, originally filed as Exhibit 2.2 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein.**†† 2.3 Asset Purchase Agreement, dated as of May 16, 2009, between Cambridge Laboratories (Ireland) Limited and Biovail Laboratories International (Barbados) SRL (the ‘‘Cambridge Asset Purchase Agreement’’), originally filed as Exhibit 2.3 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein.**†† 2.4 Amendment No. 1 to Cambridge Asset Purchase Agreement, dated as of June 19, 2009, between Cambridge Laboratories (Ireland) Limited and Biovail Laboratories International (Barbados) SRL, originally filed as Exhibit 2.4 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 2.5 Membership Interest Purchase Agreement, dated May 3, 2010, by and among Valeant, Princeton Pharma Holdings LLC and the other parties named therein, originally filed as Exhibit 2.1 to Valeant’s Current Report on Form 8-K filed on June 2, 2010, which is incorporated by reference herein.**†† 2.6 Agreement and Plan of Merger, dated as of June 20, 2010, among Valeant, the Company, Biovail Americas Corp. and Beach Merger Corp., originally filed as Exhibit 2.1 to the Company’s Current Report on Form 8-K filed on June 23, 2010, which is incorporated by reference herein.†† 2.7* Stock Purchase Agreement, dated January 31, 2011, between Biovail International S.`a.r.l. and the stockholders of PharmaSwiss SA.**†† 2.8* Asset Purchase Agreement, dated February 2, 2011, between Biovail Laboratories International SRL and GlaxoSmithKline LLC.**†† 2.9 Purchase Agreement, dated as of April 30, 2010, between Valeant and ValueAct Capital Master Fund, L.P., originally filed as Exhibit 99.1 to Valeant’s Current Report on Form 8-K, filed May 3, 2010, which is incorporated by reference herein.†† 2.10* Purchase Agreement, dated as of February 24, 2011, between the Company and ValueAct Capital Master Fund, L.P.†† 3.1 Articles of Amendment to the Articles of Continuance of Biovail Corporation (now Valeant Pharmaceuticals International, Inc.), dated September 28, 2010, originally filed as Exhibit 3.1 to the Company’s Current Report on Form 8-K filed on October 1, 2010, which is incorporated by reference herein. 3.2 Articles of Continuance of Biovail Corporation (now Valeant Pharmaceuticals International, Inc.), originally filed as Exhibit 3.1 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 3.3 Amended and Restated By-Law No. 1 of Biovail Corporation (now Valeant Pharmaceuticals International, Inc.), originally filed as Exhibit 3.2 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 83 Exhibit Number Exhibit Description 3.4 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 By-Law No. 2 of Biovail Corporation (now Valeant Pharmaceuticals International, Inc.), originally filed as Exhibit 3.3 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. Indenture, dated November 19, 2003, between Valeant, Ribapharm Inc. and The Bank of New York Mellon Trust Company, N.A, as successor to The Bank of New York Mellon (formerly The Bank of New York), originally filed as Exhibit 4.3 to the Company’s Current Report on Form 8-K filed on October 1, 2010, which is incorporated by reference herein. First Supplemental Indenture dated as of September 27, 2010, and effective as of September 28, 2010, to the Indenture dated as of November 19, 2003, between Valeant, Ribapharm Inc. and The Bank of New York Mellon Trust Company, N.A, as successor to The Bank of New York Mellon (formerly the Bank of New York) (the ‘‘Convertible Notes Trustee’’), between Valeant, the Company and the Convertible Notes Trustee, originally filed as Exhibit 4.2 to the Company’s Current Report on Form 8-K filed on October 1, 2010, which is incorporated by reference herein. Form of 4.0% Convertible Subordinated Notes due 2013, originally filed as Exhibit A-2 to Exhibit 4.1 to Valeant’s Current Report on Form 8-K, originally filed November 25, 2003 (031023410), which is incorporated by reference herein. Indenture, dated as of June 10, 2009, among the Company, The Bank of New York Mellon and BNY Trust Company of Canada, relating to the 5.375% Senior Convertible Notes due 2014, originally filed as Exhibit 4.1 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. Form of 5.375% Senior Convertible Notes due 2014, originally filed as Exhibit 4.2 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. Indenture, dated as of September 28, 2010, among Valeant, the Company, The Bank of New York Mellon Trust Company, N.A., as trustee, and the Guarantors listed therein, originally filed as Exhibit 4.1 to the Company’s Current Report on Form 8-K filed on October 1, 2010, which is incorporated by reference herein. Indenture, dated as of November 23, 2010, by and among Valeant, the Company, the guarantors named therein and The Bank of New York Mellon Trust Company, N.A., as Trustee, originally filed as Exhibit 4.1 to the Company’s Current Report on Form 8-K filed on November 26, 2010, which is incorporated by reference herein. Indenture, dated as of February 8, 2011, by and among Valeant, the Company, the guarantors named therein and The Bank of New York Mellon Trust Company, N.A., as Trustee, originally filed as Exhibit 4.1 to the Company’s Current Report on Form 8-K filed on February 9, 2010, which is incorporated by reference herein. 10.1† Biovail Corporation 2007 Equity Compensation Plan (the ‘‘2007 Equity Compensation Plan’’) dated as of May 16, 2007, originally filed as Exhibit 10.49 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.2† Amendment No. 1 to the 2007 Equity Compensation Plan dated as of December 18, 2008, originally filed as Exhibit 10.50 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.3† Biovail Corporation Amended and Restated 2004 Stock Option Plan dated as of June 25, 2004 (the ‘‘2004 Stock Option Plan’’), originally filed as Exhibit 10.51 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 84 Exhibit Number Exhibit Description 10.4† Amendment to the 2004 Stock Option Plan dated March 14, 2007, originally filed as Exhibit 10.52 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.5† Amendment to the 2004 Stock Option Plan dated May 16, 2007, originally filed as Exhibit 10.53 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.6† Biovail Corporation Deferred Share Unit Plan for Canadian Directors, approved on May 3, 2005, as amended, originally filed as Exhibit 10.57 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.7† Biovail Corporation Deferred Share Unit Plan for U.S. Directors, approved on May 3, 2005, as amended and restated, originally filed as Exhibit 10.58 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.8† Biovail Americas Corp. Executive Deferred Compensation Plan, as amended and restated effective January 1, 2009, originally filed as Exhibit 10.60 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.9† Biovail Corporation Short-Term Incentive Plan, as amended and restated effective January 1, 2009, originally filed as Exhibit 10.61 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.10† Special Dividend Reinvestment Plan of the Company, originally filed as Exhibit 4.6 to the Company’s Registration Statement on Form S-3 filed November 9, 2010, which is incorporated by reference herein. 10.11† Description of Valeant’s annual incentive plan for fiscal year 2010, previously described in Item 5.02 of Valeant’s Current Report on Form 8-K, filed January 11, 2010, which is incorporated by reference herein. 10.12† Employment Agreement, dated as of June 20, 2010, by and between the Company, Biovail Laboratories International SRL and J. Michael Pearson, originally filed as Exhibit 10.3 to the Company’s Current Report on Form 8-K filed on June 23, 2010, which is incorporated by reference herein. 10.13† Employment Letter, dated November 11, 2010, between the Company and Rajiv De Silva, originally filed as Exhibit 10.1 of the Company’s Current Report on Form 8-K filed on November 17, 2010, which is incorporated by reference herein. 10.14† Employment Letter, dated November 11, 2010, between the Company and Robert Chai-Onn, originally filed as Exhibit 10.3 to the Company’s Current Report on Form 8-K filed on November 17, 2010, which is incorporated by reference herein. 10.15† Employment Letter, dated November 11, 2010, between the Company and Mark Durham, originally filed as Exhibit 10.4 to the Company’s Current Report on Form 8-K filed on November 17, 2010, which is incorporated by reference herein. 10.16† Biovail Corporation Non-Executive Chairman and Biovail Laboratories International SRL President Agreement, dated as of June 20, 2010, among the Company, Biovail Laboratories International SRL and William M. Wells, originally filed as Exhibit 10.4 to the Company’s Current Report on Form 8-K filed on June 23, 2010, which is incorporated by reference herein. 10.17† Separation Agreement between Valeant Pharmaceuticals International, Inc., and William M. Wells, originally filed as Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on December 14, 2010, which is incorporated by reference herein. 85 Exhibit Number Exhibit Description 10.18† Separation Agreement between Valeant Pharmaceuticals International, Inc., Biovail Laboratories International SRL, and William M. Wells, originally filed as Exhibit 10.2 to the Company’s Current Report on Form 8-K filed on December 14, 2010, which is incorporated by reference herein. 10.19† Employment Letter, dated November 11, 2010, between the Company and Margaret Mulligan, originally filed as Exhibit 10.2 to the Company’s Current Report on Form 8-K filed on November 17, 2010, which is incorporated by reference herein. 10.20† Separation Agreement, dated December 20, 2010, between the Company and Margaret Mulligan, originally filed as Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on December 27, 2010, which is incorporated by reference herein. 10.21† Consulting Agreement, dated December 23, 2010, between the Company and Margaret Mulligan, originally filed as Exhibit 10.2 to the Company’s Current Report on Form 8-K filed on December 27, 2010, which is incorporated by reference herein. 10.22† Amended and Restated Employment Agreement of Gilbert Godin effective July 3, 2009, originally filed as Exhibit 10.41 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.23† Employment Agreement of Gregory Gubitz effective July 3, 2009, originally filed as Exhibit 10.42 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. 10.24 Credit and Guaranty Agreement, dated as of September 27, 2010, among Valeant, the Company, and certain subsidiaries of the Company, as Guarantors, each of the lenders named therein, Goldman Sachs Lending Partners LLC (‘‘GSLP’’), Morgan Stanley Senior Funding, Inc. and Jefferies Finance LLC, as Joint Lead Arrangers, Joint Bookrunners and Syndication Agents, GSLP, as Administrative Agent and Collateral Agent, and each of Bank of America, N.A., DnB NOR Bank ASA, SunTrust Bank and The Bank of Nova Scotia, as Documentation Agent (the ‘‘Credit Agreement’’), originally filed as Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on October 1, 2010, which is incorporated by reference herein. 10.25* Amendment No. 1 to the Credit Agreement, dated December 31, 2010. 10.26 10.27 10.28 10.29 Counterpart Agreement, dated as of September 28, 2010, between the Company and Goldman Sachs Lending Partners LLC, as Administrative Agent and Collateral Agent, originally filed as Exhibit 10.2 to the Company’s Current Report on Form 8-K filed on October 1, 2010, which is incorporated by reference herein. Credit and Guaranty Agreement, dated as of May 26, 2010, among Valeant, the guarantors named therein, Goldman Sachs Bank USA and the other parties named therein, originally filed as Exhibit 10.1 to Valeant’s Current Report on Form 8-K filed on June 2, 2010, which is incorporated by reference herein.†† Pledge and Security Agreement, dated May 26, 2010, by and among Valeant, Goldman Sachs Bank USA and the other grantors named therein, originally filed as Exhibit 10.2 to Valeant’s Current Report on Form 8-K filed on June 2, 2010, which is incorporated by reference herein.†† Credit Agreement, dated as of June 9, 2009, among the Company, JPMorgan Chase Bank, N.A., Toronto Branch, J.P. Morgan Securities Inc. and Scotia Capital Inc., The Bank of Nova Scotia and National Bank of Canada and HSBC Bank Canada and The Toronto-Dominion Bank, originally filed as Exhibit 10.36 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein.** 86 Exhibit Number 10.30 Exhibit Description Trademark License Agreement, dated as of May 14, 2009, by and between SmithKline Beecham Corporation and Biovail Laboratories International SRL, originally filed as Exhibit 10.1 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein.** 10.31* Trademark and Domain Name License Agreement, dated as of February 22, 2011, by and between GlaxoSmithKline LLC and Biovail Laboratories International SRL. 10.32 10.33 10.34 10.35 10.36 10.37 10.38 10.39 License Agreement, dated as of February 9, 2007, among GlaxoSmithKline, PLC, SmithKline Beecham Corporation and Andrx Pharmaceuticals LLC, originally filed as Exhibit 10.2 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein.** Plea Agreement and Side Letter, dated as of May 16, 2008, between United States Attorney for the District of Massachusetts and Biovail Pharmaceuticals, Inc., originally filed as Exhibit 10.30 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. Corporate Integrity Agreement, dated as of September 11, 2009, between the Company and the Office of Inspector General of the Department of Health and Human Services, originally filed as Exhibit 10.31 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. Settlement Agreement, dated as of September 11, 2009, among the United States of America, United States Department of Justice, Office of Inspector General of the Department of Health and Human Services and the Company, originally filed as Exhibit 10.32 to the Company’s Annual Report on Form 10-K filed for the fiscal year ended December 31, 2009, which is incorporated by reference herein. Securities Litigation, Stipulation and Agreement of Settlement, dated as of April 4, 2008, between the United States District Court, Southern District of New York and the Company, originally filed as Exhibit 10.33 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. Settlement Agreement, dated January 7, 2009, between Staff of the Ontario Securities Commission and the Company, originally filed as Exhibit 10.34 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. Settlement Agreement, dated March 2008, between the U.S. Securities and Exchange Commission and the Company, originally filed as Exhibit 10.35 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009, which is incorporated by reference herein. Commitment Letter, dated as of June 20, 2010, among Valeant, the Company, Goldman Sachs Lenders Partners LLC, Goldman Sachs Bank USA, Morgan Stanley Senior Funding, Inc. and Jefferies Finance LLC, originally filed as Exhibit 10.1 of the Company’s Current Report on Form 8-K filed on June 23, 2010, which is incorporated by reference herein. 10.40 Voting Agreement, dated as of June 20, 2010, among Valeant, the Company and ValueAct, Inc., originally filed as Exhibit 10.2 to the Company’s Current Report on Form 8-K filed on June 23, 2010, which is incorporated by reference herein. 10.41 Asset Purchase Agreement, dated as of January 22, 2004, by and between Xcel Pharmaceuticals, Inc. and VIATRIS GmbH and Co. KG., originally filed as Exhibit 10.7 to Valeant’s Quarterly Report on Form 10-Q for the quarter ended March 31, 2005 (05816114), which is incorporated by reference herein.**†† 87 Exhibit Number 10.42 10.43 Exhibit Description License and Collaboration Agreement, dated as of August 27, 2008, between Valeant Pharmaceuticals North America and Glaxo Group Limited (the ‘‘GSK Retigabine Agreement’’), originally filed as Exhibit 10.1 to Valeant’s Current Report on Form 8-K/A, filed August 29, 2008, which is incorporated by reference herein.** First Amendment to the GSK Retigabine Agreement, dated as of February 10, 2009, between Valeant Pharmaceuticals North America and Glaxo Group Limited, originally filed as Exhibit 10.35 to Valeant’s Annual Report on Form 10-K for the year ended December 31, 2008, which is incorporated by reference herein.** 10.44*† Form of Stock Option Grant Notice and Form of Stock Option Grant Agreement under the 2007 Equity Compensation Plan. 10.45*† Form of Unit Grant Notice and Form of Unit Grant Agreement under the 2007 Equity Compensation Plan. 10.46*† Form of Unit Grant Notice (Performance Vesting) and Form of Unit Grant Agreement (Performance Vesting) under the 2007 Equity Compensation Plan. 14.1* Valeant Pharmaceuticals International, Inc. — Code of Ethics for the Chief Executive Officer and Senior Finance Executives. 16.1 Letter, dated November 26, 2010, from Ernst & Young LLP, originally filed as Exhibit 16.1 of the Company’s Current Report on Form 8-K filed on November 26, 2010, which is incorporated by reference herein. 21.1* Subsidiaries of Valeant Pharmaceuticals International, Inc. 23.1* Consent of Ernst & Young LLP. 31.1* Certification of the Chief Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. 31.2* Certification of the Chief Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. 32.1* Certificate of the Chief Executive Officer of Valeant Pharmaceuticals International, Inc. pursuant to 18 U.S.C. § 1350 as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. 32.2* Certificate of the Chief Financial Officer of Valeant Pharmaceuticals International, Inc. pursuant to 18 U.S.C. § 1350 as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. * ** Filed herewith. Portions of this exhibit have been omitted pursuant to an application for confidential treatment. Such information has been omtted and filed separately with the SEC. † Management contract or compensatory plan or arrangement. †† One or more exhibits or schedules to this exhibit have been omitted pursuant to Item 601(b)(2) of Regulation S-K. We undertake to furnish supplementally a copy of any omitted exhibit or schedule to the SEC upon request. 88 Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized. SIGNATURES Date: February 28, 2011 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. (Registrant) By: /s/ J. MICHAEL PEARSON J. Michael Pearson Chief Executive Officer (Principal Executive Officer) Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated. Signature Title Date /s/ ROBERT A. INGRAM Robert A. Ingram /s/ J. MICHAEL PEARSON J. Michael Pearson Chairman of the Board February 28, 2011 Chief Executive Officer and Director February 28, 2011 /s/ PHILIP W. LOBERG Philip W. Loberg Executive Vice-President, Interim Chief Financial Officer (Principal Financial Officer and Principal Accounting Officer) February 28, 2011 /s/ THEO MELAS-KYRIAZI Theo Melas-Kyriazi /s/ G. MASON MORFIT G. Mason Morfit /s/ DR. LAURENCE E. PAUL Dr. Laurence E. Paul /s/ ROBERT N. POWER Robert N. Power /s/ NORMA A. PROVENCIO Norma A. Provencio Director February 28, 2011 Director February 28, 2011 Director February 28, 2011 Director February 28, 2011 Director February 28, 2011 89 Signature Title Date /s/ LLOYD M. SEGAL Lloyd M. Segal /s/ KATHARINE B. STEVENSON Katharine B. Stevenson /s/ MICHAEL R. VAN EVERY Michael R. Van Every Director February 28, 2011 Director February 28, 2011 Director February 28, 2011 90 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. INDEX TO CONSOLIDATED FINANCIAL STATEMENTS Report of Management on Financial Statements and Internal Control Over Financial Reporting . . . . . Report of Independent Registered Public Accounting Firm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Report of Independent Registered Public Accounting Firm on Internal Control Over Financial Reporting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Consolidated Balance Sheets as of December 31, 2010 and 2009 . . . . . . . . . . . . . . . . . . . . . . . . . . . . Consolidated Statements of Income (Loss) for the years ended December 31, 2010, 2009 and 2008 . . . Consolidated Statements of Shareholders’ Equity for the years ended December 31, 2010, 2009 and 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Consolidated Statements of Cash Flows for the years ended December 31, 2010, 2009 and 2008 . . . . . Notes to Consolidated Financial Statements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Page F-2 F-3 F-4 F-5 F-6 F-7 F-8 F-9 F-1 REPORT OF MANAGEMENT ON FINANCIAL STATEMENTS AND INTERNAL CONTROL OVER FINANCIAL REPORTING Financial Statements The Company’s management is responsible for preparing the accompanying consolidated financial statements in conformity with United States generally accepted accounting principles (‘‘U.S. GAAP’’). In preparing these consolidated financial statements, management selects appropriate accounting policies and uses its judgment and best estimates to report events and transactions as they occur. Management has determined such amounts on a reasonable basis in order to ensure that the consolidated financial statements are presented fairly, in all material respects. Financial information included throughout this Annual Report is prepared on a basis consistent with that of the accompanying consolidated financial statements. Ernst & Young LLP has been engaged by the Company’s shareholders to audit the consolidated financial statements. The Board of Directors is responsible for ensuring that management fulfills its responsibility for financial reporting and is ultimately responsible for reviewing and approving the consolidated financial statements. The Board of Directors carries out this responsibility principally through its Finance and Audit Committee. The members of the Finance and Audit Committee are outside Directors. The Finance and Audit Committee considers, for review by the Board of Directors and approval by the shareholders, the engagement or reappointment of the external auditors. Ernst & Young LLP has full and free access to the Finance and Audit Committee. Management acknowledges its responsibility to provide financial information that is representative of the Company’s operations, is consistent and reliable, and is relevant for the informed evaluation of the Company’s activities. Internal Control Over Financial Reporting The Company’s management is responsible for establishing and maintaining adequate internal control over financial reporting as defined in Rules 13a-15(f) and 15d-15(f) under the Securities Exchange Act of 1934. The Company’s internal accounting controls systems are designed to provide reasonable assurance that assets are safeguarded, that transactions are executed in accordance with management’s authorization and are properly recorded, and that accounting records are adequate for preparation of financial statements in accordance with U.S. GAAP and other financial information. Under the supervision and with the participation of management, including the Company’s Chief Executive Officer and Chief Financial Officer, the Company conducted an evaluation of the effectiveness of its internal control over financial reporting based on the framework in Internal Control — Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission. Based on its evaluation under this framework, management concluded that the Company’s internal controls over financial reporting were effective as of December 31, 2010. The scope of management’s assessment of the effectiveness of internal control over financial reporting includes all of the Company’s consolidated operations except for the operations of Valeant Pharmaceuticals International (‘‘Valeant’’), which the Company acquired on September 28, 2010. Valeant’s operations represented 23% of the Company’s consolidated revenues for the year ended December 31, 2010, and assets associated with Valeant’s operations (excluding intangible assets, goodwill and other fair value adjustments arising from the acquisition accounting for Valeant) represented 11% of the Company’s consolidated total assets as of December 31, 2010. The effectiveness of the Company’s internal control over financial reporting as of December 31, 2010 has been audited by Ernst & Young LLP, as stated in their report on page F-4 herein. /s/ J. MICHAEL PEARSON J. Michael Pearson Chief Executive Officer February 28, 2011 F-2 /s/ PHILIP W. LOBERG Philip W. Loberg Executive Vice President and Interim Chief Financial Officer REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM To the Board of Directors and Shareholders of Valeant Pharmaceuticals International, Inc. We have audited the accompanying consolidated balance sheets of Valeant Pharmaceuticals International, Inc., formerly Biovail Corporation, as of December 31, 2010 and 2009, and the related consolidated statements of income (loss), shareholders’ equity, and cash flows for each of the three years in the period ended December 31, 2010. Our audits also included the financial statement schedule II included in Item 15. These financial statements and schedule are the responsibility of the Company’s management. Our responsibility is to express an opinion on these financial statements and schedule based on our audits. We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion. In our opinion, the financial statements referred to above present fairly, in all material respects, the consolidated financial position of Valeant Pharmaceuticals International, Inc. at December 31, 2010 and 2009, and the consolidated results of its operations and its cash flows for each of the three years in the period ended December 31, 2010, in conformity with United States generally accepted accounting principles. Also, in our opinion, the related financial statement schedule, when considered in relation to the basic financial statements taken as a whole, presents fairly, in all material respects, the information set forth therein. We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States), the effectiveness of Valeant Pharmaceuticals International, Inc.’s internal control over financial reporting as of December 31, 2010, based on criteria established in the Internal Control — Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission and our report dated February 28, 2011 expressed an unqualified opinion thereon. Toronto, Canada, February 28, 2011 /s/ ERNST & YOUNG LLP Chartered Accountants Licensed Public Accountants F-3 REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM ON INTERNAL CONTROL OVER FINANCIAL REPORTING To the Board of Directors and Shareholders of Valeant Pharmaceuticals International, Inc. We have audited internal control over financial reporting of Valeant Pharmaceuticals International, Inc., formerly Biovail Corporation, as of December 31, 2010, based on criteria established in Internal Control — Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (the ‘‘COSO’’ criteria). Valeant Pharmaceuticals International, Inc.’s management is responsible for maintaining effective internal control over financial reporting, and for its assessment of the effectiveness of internal control over financial reporting included in the accompanying Management’s Report on Internal Control Over Financial Reporting. Our responsibility is to express an opinion on the Company’s internal control over financial reporting based on our audit. We conducted our audit in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether effective internal control over financial reporting was maintained in all material respects. Our audit included obtaining an understanding of internal control over financial reporting, assessing the risk that a material weakness exists, testing and evaluating the design and operating effectiveness of internal control based on the assessed risk, and performing such other procedures as we considered necessary in the circumstances. We believe that our audit provides a reasonable basis for our opinion. A company’s internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles. A company’s internal control over financial reporting includes those policies and procedures that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the assets of the company; (2) provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with generally accepted accounting principles, and that receipts and expenditures of the company are being made only in accordance with authorizations of management and directors of the company; and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company’s assets that could have a material effect on the financial statements. Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate. In our opinion, Valeant Pharmaceuticals International, Inc. maintained, in all material respects, effective internal control over financial reporting as of December 31, 2010, based on the COSO criteria. As indicated in the accompanying Management’s Report on Internal Control Over Financial Reporting, management’s assessment of and conclusion on the effectiveness of internal control over financial reporting did not include the internal controls of Valeant Pharmaceuticals International (‘‘Valeant’’), which is included in the 2010 consolidated financial statements of Valeant Pharmaceuticals International, Inc. Valeant’s operations represented 23% of the Company’s consolidated revenues for the year ended December 31, 2010, and assets associated with Valeant’s operations (excluding intangible assets, goodwill and other fair value adjustments arising from the acquisition accounting for Valeant) represented 11% of the Company’s consolidated total assets as of December 31, 2010. Our audit of internal control over financial reporting of Valeant Pharmaceuticals International, Inc. also did not include an evaluation of the internal control over financial reporting of Valeant Pharmaceuticals International. We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States), the accompanying consolidated balance sheets of Valeant Pharmaceuticals International, Inc. as of December 31, 2010 and 2009, and the related consolidated statements of income (loss), shareholders’ equity, and cash flows for each of the three years in the period ended December 31, 2010, and our report dated February 28, 2011, expressed an unqualified opinion thereon. Toronto, Canada, February 28, 2011 /s/ ERNST & YOUNG LLP Chartered Accountants Licensed Public Accountants F-4 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. CONSOLIDATED BALANCE SHEETS (All dollar amounts expressed in thousands of U.S. dollars) Assets Current assets: Cash and cash equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Marketable securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Accounts receivable, net Inventories, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Prepaid expenses and other current assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Assets held for sale . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Income taxes receivable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Deferred tax assets, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ Total current assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Marketable securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Property, plant and equipment, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Intangible assets, net Goodwill . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Deferred tax assets, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other long-term assets, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . As of December 31 2010 2009 394,269 6,083 274,819 229,582 26,088 4,014 8,243 77,068 1,020,166 2,083 281,752 6,372,780 3,001,376 80,085 36,875 $ 114,463 9,566 112,165 82,773 15,377 8,542 — — 342,886 11,516 103,848 1,335,222 100,294 132,800 32,724 Total assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $10,795,117 $2,059,290 Liabilities Current liabilities: Accounts payable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Dividends payable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Accrued liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Income taxes payable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Deferred revenue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Current portion of long-term debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Liabilities for uncertain tax positions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Deferred tax liabilities, net $ Total current liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Deferred revenue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Long-term debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Liabilities for uncertain tax positions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Deferred tax liabilities, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other long-term liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Total liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Shareholders’ Equity Common shares, no par value, unlimited shares authorized, 302,448,934 and 101,324 — 442,114 9,153 21,520 116,900 646 799 692,456 50,021 3,478,377 96,102 1,436,743 130,322 5,884,021 $ 72,022 14,246 122,094 6,846 21,834 12,110 — — 249,152 69,247 313,975 66,200 — 6,344 704,918 158,310,884 issued and outstanding at December 31, 2010 and 2009, respectively . . . . Additional paid-in capital . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Accumulated deficit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Accumulated other comprehensive income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5,251,730 495,041 (934,511) 98,836 1,465,004 91,768 (245,974) 43,574 Total shareholders’ equity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4,911,096 1,354,372 Total liabilities and shareholders’ equity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $10,795,117 $2,059,290 Commitments and contingencies (notes 24, 25 and 27) On behalf of the Board: /s/ J. MICHAEL PEARSON J. Michael Pearson Chief Executive Officer /s/ MICHAEL R. VAN EVERY Michael R. Van Every Chairperson, Finance and Audit Committee The accompanying notes are an integral part of these consolidated financial statements. F-5 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. CONSOLIDATED STATEMENTS OF INCOME (LOSS) (All dollar amounts expressed in thousands of U.S. dollars, except per share data) Revenues Product sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Alliance and royalty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Service and other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Expenses Cost of goods sold (exclusive of amortization of intangible assets shown separately below) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cost of services . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Research and development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Selling, general and administrative . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Amortization of intangible assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Restructuring and other costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Acquired in-process research and development . . . . . . . . . . . . . . . . . . . . Legal settlements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Acquisition-related costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Operating income (loss) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Interest income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Interest expense . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Write-down of deferred financing costs . . . . . . . . . . . . . . . . . . . . . . . . . Foreign exchange and other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Loss on extinguishment of debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Gain (loss) on investments, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Income (loss) before recovery of income taxes . . . . . . . . . . . . . . . . . . . . Recovery of income taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Years Ended December 31 2010 2009 2008 $1,133,371 35,109 12,757 $789,026 15,418 15,986 $714,548 16,119 26,511 1,181,237 820,430 757,178 395,595 10,155 68,311 276,546 219,758 140,840 89,245 52,610 38,262 204,309 13,849 47,581 167,633 104,730 30,033 59,354 6,191 5,596 197,167 23,033 69,811 188,922 51,369 70,202 — 32,565 — 1,291,322 639,276 633,069 (110,085) 1,294 (84,307) (5,774) 574 (32,413) (5,552) (236,263) (28,070) 181,154 1,118 (24,881) (537) 507 — 17,594 174,955 (1,500) 124,109 9,400 (1,018) — (1,057) — (4,530) 126,904 (73,000) Net income (loss) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ (208,193) $176,455 $199,904 Basic and diluted earnings (loss) per share . . . . . . . . . . . . . . . . . . . . . . . $ (1.06) $ 1.11 $ 1.25 Weighted-average common shares (000’s) Basic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Diluted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195,808 195,808 158,236 158,510 159,730 159,730 Cash dividends declared per share . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 1.280 $ 0.645 $ 1.500 The accompanying notes are an integral part of these consolidated financial statements. F-6 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. CONSOLIDATED STATEMENTS OF SHAREHOLDERS’ EQUITY (All dollar amounts expressed in thousands of U.S. dollars) Common Shares Shares (000s) Amount Additional Paid-In Capital Accumulated Other Accumulated Comprehensive Deficit Income Total Balance, January 1, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161,024 $1,489,807 $ 23,925 . . . . . . . . . . . . . . . . . . . . . . . . . . Repurchase of common shares Common shares issued under share-based compensation plans . . . . . . . Share-based compensation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . — Cash dividends declared and dividend equivalents ($1.50 per share) . . . . — . . . . . . . . . . . . . . . . . . . . . . . . . . . — Cumulative effect adjustment (2,818) 10 (26,077) — (143) 7,906 278 — — — 143 — $(278,495) (3,765) — — (239,896) 2,343 $ 62,582 — — — — — $1,297,819 (29,842) — 7,906 (239,618) 2,343 158,216 1,463,873 31,966 (519,813) 62,582 1,038,608 Comprehensive income: Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . — Other comprehensive loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . — — — — — 199,904 — — (36,913) Total comprehensive income . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199,904 (36,913) 162,991 Balance, December 31, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158,216 1,463,873 31,966 (319,909) 25,669 1,201,599 Equity component of 5.375% Convertible Notes, net of issuance costs Common shares issued under share-based compensation plans . . . . . . . Share-based compensation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . — Cash dividends declared and dividend equivalents ($0.645 per share) . . . — . . — 95 — 1,131 — — 53,995 (265) 5,613 459 — — — (102,520) — — — — 53,995 866 5,613 (102,061) Comprehensive income: Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . — Other comprehensive income . . . . . . . . . . . . . . . . . . . . . . . . . . — — — — — 176,455 — — 17,905 Total comprehensive income . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176,455 17,905 194,360 Balance, December 31, 2009 . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158,311 1,465,004 91,768 (245,974) 43,574 1,354,372 158,311 1,465,004 91,768 (422,429) 25,669 1,160,012 Acquisition of Valeant, equity issued . . . . . . . . . . . . . . . . . . . . . . . 139,267 Fair value of equity component of Valeant 4.0% Convertible Notes and call options . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . — Equity settlement and reclassification of call options . . . . . . . . . . . . . Repurchase of equity component of 5.375% Convertible Notes . . . . . . . — Common shares issued under share-based compensation plans . . . . . . . Employee withholding taxes related to share-based awards Repurchase of common shares Share-based compensation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . — Cash dividends declared and dividend equivalents ($1.28 per share) . . . . — Cash dividends reinvested through dividend reinvestment plan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . — 145 6,959 72 (2,305) 3,710,888 169,413 — 253,971 (38,224) (20,444) (52,088) (14,485) — 3,602 — 110,513 — (40,442) — — — 2,165 98,033 7,097 — — 1,928 (111,279) — — (19,688) — (349,140) (2,165) — — — — — — — — — — 3,880,301 253,971 (32,694) (131,723) 58,425 (14,485) (60,130) 98,033 (342,043) — Comprehensive loss: Net loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . — Other comprehensive income . . . . . . . . . . . . . . . . . . . . . . . . . . — — — — — (208,193) — — 55,262 Total comprehensive loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (208,193) 55,262 (152,931) Balance, December 31, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302,449 $5,251,730 $495,041 $(934,511) $ 98,836 $4,911,096 302,449 5,251,730 495,041 (726,318) 43,574 5,064,027 The accompanying notes are an integral part of these consolidated financial statements. F-7 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. CONSOLIDATED STATEMENTS OF CASH FLOWS (All dollar amounts expressed in thousands of U.S. dollars) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cash Flows From Operating Activities Net income (loss) . . . . Adjustments to reconcile net income (loss) to net cash provided by operating activities: . . . . . . . . . . . . . . . . . . . . . Depreciation and amortization . . . Amortization of deferred revenue . . . Amortization and write-down of discounts on long-term debt . . . Amortization and write-down of deferred financing costs . . . Acquired in-process research and development . . . Acquisition accounting adjustment on inventory sold . . . . Allowances for losses on accounts receivable and inventories . . . Deferred income taxes . . . . . Additions to accrued legal settlements . . . . Payment of accrued legal settlements . . . . . Share-based compensation . . Impairment and other charges . . . . Payment of accreted interest on repurchase of 5.375% Convertible Notes . . . . Loss on extinguishment of debt . . . . Gain on disposal of investments . . . . Accrued contract costs . Other . . . . . . . . Changes in operating assets and liabilities: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Accounts receivable . Inventories . . . . Prepaid expenses and other current assets . . . Accounts payable . . . . . Accrued liabilities . Income taxes payable . . . Deferred revenue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Net cash provided by operating activities . . . . . . . . . . . Cash Flows From Investing Activities . . Acquisition of Valeant, net cash acquired . . Acquisitions, net of cash acquired . . . . Additions to property, plant and equipment Proceeds from sale of assets . . . . Proceeds from sales and maturities of marketable securities . . Additions to marketable securities . . . Proceeds on disposal of investments, net of costs . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Net cash provided by (used in) investing activities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cash Flows From Financing Activities . . Issuance of long-term debt . . . . . Repayment of long-term debt . . . . . Cash dividends paid . . Repurchase of 5.375% Convertible Notes . Repurchase of common shares . . . . Proceeds from exercise of stock options Cash settlement of call options . . . Payment of employee withholding tax upon vesting of share-based awards . . . . . . Financing costs paid . . . . Advances under credit facilities . . . . . Repayments under credit facilities . . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Net cash provided by (used in) financing activities . . . . . . . Effect of exchange rate changes on cash and cash equivalents . Net increase (decrease) in cash and cash equivalents . . Cash and cash equivalents, beginning of year . . . . Cash and cash equivalents, end of year . . . . . . . . . Non-Cash Investing and Financing Activities . . Acquisition of Valeant, equity issued . . . Acquisition of Valeant, debt assumed . Cash dividends declared but unpaid . . . . Long-term debt related to acquisition of business . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Years Ended December 31 2010 2009 2008 $ (208,193) $ 176,455 $ 199,904 254,504 (19,101) 11,169 10,303 89,245 53,266 6,887 (55,403) 52,610 (44,450) 98,033 11,603 (4,934) 30,716 — — (1,200) 25,187 7,463 7,394 (76,100) 26,732 (9,723) (2,817) 149,260 (21,201) 5,986 3,620 59,354 — 8,674 (16,000) 6,191 (30,806) 5,613 24,937 — — (804) — (177) (26,998) (33,582) (796) 30,771 32,780 726 (13,106) 102,905 (18,246) — 520 — — 4,261 (90,000) 32,565 (93,048) 7,906 69,056 — — (6,534) (45,065) 806 26,654 16,293 318 (6,135) 4,572 8,700 (11,107) 263,191 360,897 204,325 308,982 (84,532) (16,823) 15,046 7,965 — — (1,699) — (761,829) (7,423) 28,302 1,078 (3,823) — 923 — (101,920) (21,999) — 4,450 (6,290) 25,216 (7,288) 228,939 (742,772) (107,831) 992,400 (537,500) (356,291) (254,316) (60,130) 58,425 (37,682) (14,485) (4,565) — — 861 350,000 — (147,146) — — 866 — — (26,274) 130,000 (130,000) (399) — — (180,287) — (29,842) — — — — — — (182) (213,283) 177,047 (210,311) 959 279,806 114,463 1,744 (2,277) (203,084) 317,547 (116,094) 433,641 $ 394,269 $ 114,463 $ 317,547 $(3,880,301) (2,913,614) — — $ — — (14,246) (26,768) $ — — (59,331) — . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The accompanying notes are an integral part of these consolidated financial statements. F-8 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 1. DESCRIPTION OF BUSINESS On September 28, 2010 (the ‘‘Merger Date’’), Biovail Corporation (‘‘Biovail’’) completed the acquisition of Valeant Pharmaceuticals International (‘‘Valeant’’) through a wholly-owned subsidiary pursuant to an Agreement and Plan of Merger, dated as of June 20, 2010, with Valeant surviving as a wholly-owned subsidiary of Biovail (the ‘‘Merger’’). In connection with the Merger, Biovail was renamed ‘‘Valeant Pharmaceuticals International, Inc.’’ (the ‘‘Company’’). The Company is a multinational specialty pharmaceutical company that develops, manufactures and markets a broad range of pharmaceutical products primarily in the areas of neurology, dermatology and branded generics. 2. SIGNIFICANT ACCOUNTING POLICIES Basis of Presentation The consolidated financial statements have been prepared by the Company in United States (‘‘U.S.’’) dollars and in accordance with U.S. generally accepted accounting principles, applied on a consistent basis. As described in note 3, the Merger has been accounted for as a business combination under the acquisition method of accounting. Biovail was both the legal and accounting acquirer in the Merger. Accordingly, the Company’s consolidated financial statements reflect the assets, liabilities, revenues and expenses of Valeant from the Merger Date. Principles of Consolidation The consolidated financial statements include the accounts of the Company and those of its subsidiaries. All significant intercompany transactions and balances have been eliminated. The Company has entered into collaboration and license arrangements with other entities for various products under development. These arrangements typically include upfront and contingent milestone and royalty payments. All such arrangements were determined not to be variable interests in the entities. Accordingly, the Company does not consolidate the financial results of any of these entities. Acquisitions Acquired businesses are accounted for using the acquisition method of accounting, which requires that assets acquired and liabilities assumed be recorded at fair value, with limited exceptions. Any excess of the purchase price over the fair value of the net assets acquired is recorded as goodwill. Acquired in-process research and development (‘‘IPR&D’’) is recognized at fair value and initially characterized as indefinite-lived intangible assets, irrespective of whether the acquired IPR&D has an alternative future use. If the acquired net assets do not constitute a business, the transaction is accounted for as an asset acquisition and no goodwill is recognized. In an asset acquisition, the amount allocated to acquired IPR&D with no alternative future use is charged to expense at the acquisition date. Use of Estimates In preparing the Company’s consolidated financial statements, management is required to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the financial statements, and the reported amounts of revenues and expenses during the reporting periods. Significant estimates made by management include: provisions for product returns, rebates and chargebacks; useful lives of amortizable intangible assets; expected future cash flows used in evaluating intangible assets for impairment; reporting unit fair values in testing goodwill for impairment; provisions for loss contingencies; provisions for income taxes and realizability of deferred tax assets; and the allocation of the purchase price of acquired assets and businesses. Under certain product manufacturing and supply agreements, management relies on estimates for future returns, rebates and chargebacks made by the Company’s commercialization counterparties. On an ongoing basis, management reviews its estimates to ensure that these estimates appropriately reflect changes in the Company’s business and new information as it becomes available. If historical experience and other factors used by management to make these estimates do not reasonably reflect future activity, the Company’s consolidated financial statements could be materially impacted. Fair Value of Financial Instruments The estimated fair values of cash and cash equivalents, accounts receivable, accounts payable and accrued liabilities approximate their carrying values due to their short maturity periods. The fair values of marketable securities and long-term debt are based on quoted market prices, if available, or estimated discounted future cash flows. F-9 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 2. SIGNIFICANT ACCOUNTING POLICIES (Continued) Cash and Cash Equivalents Cash and cash equivalents include certificates of deposit, treasury bills, certain money-market funds, term deposits and investment- grade commercial paper with maturities of three months or less when purchased. Marketable Securities Marketable debt securities are classified as being available-for-sale. These securities are reported at fair value with all unrealized gains and temporary unrealized losses recognized in other comprehensive income. Other-than-temporary credit losses that represent a decrease in the cash flows expected to be collected on these securities are recognized in net income. Other-than-temporary non-credit losses related to all other factors are recognized in other comprehensive income, if the Company does not intend to sell the security and it is not more likely than not that it will be required to sell the security before recovery of its amortized cost basis. Realized gains and losses on the sale of these securities are recognized in net income. The cost of securities sold, and the amount reclassified out of accumulated other comprehensive income into earnings, is calculated using the specific identification method, if determinable, otherwise the average cost method is applied. The amortization of acquisition premiums or discounts is recorded as a deduction from or addition to interest income earned on these securities. Concentrations of Credit Risk Financial instruments that potentially subject the Company to significant concentrations of credit risk consist primarily of cash and cash equivalents, marketable securities and accounts receivable. The Company invests its excess cash in high-quality, liquid money market instruments with varying maturities, but typically less than three months. The Company maintains its cash and cash equivalents with major financial institutions. The Company has not experienced any significant losses on its cash or cash equivalents. The Company’s marketable securities portfolio includes investment-grade corporate, government or government-sponsored enterprise fixed income debt securities with a maximum term to maturity of three years. No single issuer comprises more than 20% of the portfolio. Concentrations of credit risk from trade receivables are limited due to the number of customers comprising the Company’s customer base, and their dispersion across geographic areas. At December 31, 2010 and 2009, the Company’s three largest U.S. wholesaler customers accounted for 46% and 69% of trade receivables, respectively. The Company performs periodic credit evaluations of customers and generally does not require collateral. An allowance for doubtful accounts is maintained for potential credit losses based on the aging of accounts receivable, historical bad debts experience, and changes in customer payment patterns. Accounts receivable balances are written off against the allowance when it is probable that the receivable will not be collected. The Company has not experienced any significant losses from uncollectible accounts in the three-year period ended December 31, 2010. Inventories Inventories comprise raw materials, work in process, and finished goods, which are valued at the lower of cost or market, on a first-in, first-out basis. Cost for work in process and finished goods inventories includes materials, direct labour, and an allocation of overheads. Market for raw materials is replacement cost, and for work in process and finished goods is net realizable value. The Company evaluates the carrying value of inventories on a regular basis, taking into account such factors as historical and anticipated future sales compared with quantities on hand, the price the Company expects to obtain for products in their respective markets compared with historical cost and the remaining shelf life of goods on hand. Property, Plant and Equipment Property, plant and equipment are reported at cost, less accumulated depreciation. Costs incurred on assets under construction are capitalized as construction in progress. Depreciation is calculated using the straight-line method, commencing when the assets become available for productive use, based on the following estimated useful lives: Buildings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Machinery and equipment . . . . . . . . . . . . . . . . . . . . . . . . Other equipment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Leasehold improvements and capital leases 20 - 40 years 3 - 20 years 3 - 10 years Lesser of term of lease or 10 years F-10 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 2. SIGNIFICANT ACCOUNTING POLICIES (Continued) Intangible Assets Intangible assets are reported at cost, less accumulated amortization. Intangible assets with finite lives are amortized over their estimated useful lives. Amortization is calculated using the straight-line method based on the following estimated useful lives: Product brands . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Corporate brands . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Product rights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Outlicensed technology and other 5 - 25 years 20 years 5 - 20 years 5 - 10 years IPR&D The fair value of IPR&D acquired through a business combination is capitalized as an indefinite-lived intangible asset until the completion or abandonment of the related research and development activities. When the related research and development is completed, the asset will be assigned a useful life and amortized. The fair value of an IPR&D intangible asset is determined using an income approach. This approach starts with a forecast of the net cash flows expected to be generated by the asset over its estimated useful life. The net cash flows reflect the asset’s stage of completion, the probability of technical success, the projected costs to complete, expected market competition, and an assessment of the asset’s life cycle. The net cash flows are then adjusted to present value by applying an appropriate discount rate that reflects the risk factors associated with the cash flow streams. Impairment of Long-Lived Assets Long-lived assets with finite lives are tested for impairment at least annually, or whenever events or changes in circumstances indicate that the carrying value of an asset may not be recoverable. Indicators of potential impairment include: an adverse change in legal factors or in the business climate that could affect the value of the asset; an adverse change in the extent or manner in which the asset is used or is expected to be used, or in its physical condition; and current or forecasted operating or cash flow losses that demonstrate continuing losses associated with the use of the asset. If indicators of impairment are present, the asset is tested for recoverability by comparing the carrying value of the asset to the related estimated undiscounted future cash flows expected to be derived from the asset. If the expected cash flows are less than the carrying value of the asset, then the asset is considered to be impaired and its carrying value is written down to fair value, based on the related estimated discounted future cash flows. Indefinite-lived intangible assets, including acquired IPR&D, are tested for impairment annually or more frequently if events or changes in circumstances between annual tests indicate that the asset may be impaired. Impairment losses on indefinite-lived intangible assets are recognized based solely on a comparison of the fair value of the asset to its carrying value, without consideration of any recoverability test. Goodwill Goodwill represents the excess of the purchase price of acquired businesses over the estimated fair value of the identifiable net assets acquired. Goodwill is not amortized but is tested for impairment at least annually at the reporting unit level. A reporting unit is the same as, or one level below, an operating segment. Prior to the Merger, the Company had one operating segment and one reporting unit. Accordingly, for fiscal years 2010 and 2009, goodwill existing prior to the Merger was tested for impairment by comparing the Company’s pre-Merger market capitalization to the carrying value of its consolidated net assets. On that basis, there was no indication of goodwill impairment. Effective with the Merger, the Company operates in the following business segments: U.S. Neurology and Other; U.S. Dermatology; Canada and Australia; Branded Generics — Europe; and Branded Generics — Latin America. Each of the U.S. Neurology and Other, U.S. Dermatology and Branded Generics — Europe segments consist of one reporting unit. The Canada and Australia segment consists of two geographical reporting units. Similarly, the Branded Generics — Latin America segment consists of two reporting units based on geography, namely Mexico and Brazil. The Company has provisionally allocated goodwill to the seven reporting units. Goodwill recognized as a result of the Merger will be tested for impairment commencing in 2011. Deferred Financing Costs Deferred financing costs are reported at cost, less accumulated amortization, and are recorded in other long-term assets. Amortization expense is included in interest expense. F-11 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 2. SIGNIFICANT ACCOUNTING POLICIES (Continued) Derivative Financial Instruments From time to time, the Company utilizes derivative financial instruments to manage its exposure to market risks, including foreign currency and interest rate exposures. The Company does not utilize derivative financial instruments for trading or speculative purposes, nor does it enter into trades for which there is no underlying exposure. Derivative financial instruments are recorded as either assets or liabilities at fair value. The Company accounts for derivative financial instruments based on whether they meet the criteria for designation as hedging transactions, either as cash flow, net investment, or fair value hedges. Depending on the nature of the hedge, changes in the fair value of a hedged item are either offset against the change in the fair value of the hedged item through earnings or recognized in other comprehensive income until the hedged item is recognized in earnings. The Company did not hold any derivative financial instruments at December 31, 2010 or 2009. Foreign Currency Translation The assets and liabilities of the Company’s foreign operations having a functional currency other than the U.S. dollar are translated into U.S. dollars at the exchange rate prevailing at the balance sheet date, and at the average exchange rate for the reporting period for revenue and expense accounts. The cumulative foreign currency translation adjustment is recorded as a component of accumulated other comprehensive income in shareholders’ equity. Foreign currency exchange gains and losses on transactions occurring in a currency other than an operation’s functional currency are recognized in net income. Revenue Recognition Revenue is realized or realizable and earned when persuasive evidence of an arrangement exists, delivery has occurred or services have been rendered, the price to the customer is fixed or determinable, and collectibility is reasonably assured. Product Sales Product sales revenue is recognized when title has transferred to the customer and the customer has assumed the risks and rewards of ownership. Amounts received from customers as prepayments for products to be shipped in the future are recorded in deferred revenue. Revenue from product sales is recognized net of provisions for estimated discounts, allowances, returns, rebates and chargebacks. The Company offers discounts for prompt payment and other incentive allowances to customers. Provisions for discounts and allowances are estimated based on contractual sales terms with customers and historical payment experience. The Company allows customers to return product within a specified period of time before and after its expiration date. Provisions for returns are estimated based on historical return levels, taking into account additional available information on competitive products and contract changes. The Company has data sharing agreements with the three largest wholesalers in the U.S. Where the Company does not have data sharing agreements, it uses third-party data to estimate the level of product inventories and product demand at wholesalers and retail pharmacies. The Company reviews its methodology and adequacy of the provision for returns on a quarterly basis, adjusting for changes in assumptions, historical results and business practices, as necessary. The Company is subject to rebates on sales made under governmental and commercial rebate programs, and chargebacks on sales made to government agencies, retail pharmacies and group purchasing organizations. Provisions for rebates and chargebacks are estimated based on historical experience, relevant statutes with respect to governmental pricing programs, and contractual sales terms. The Company is party to manufacturing and supply agreements with a number of commercialization counterparties in the U.S. Under the terms of these agreements, the Company’s supply prices for its products are determined after taking into consideration estimates for future returns, rebates, and chargebacks provided by each counterparty. The Company makes adjustments as needed to state these estimates on a basis consistent with this policy, and its methodology for estimating returns, rebates and chargebacks related to its own direct product sales. Alliance and Royalty The Company earns royalties and profit share revenue as a result of the licensing of product rights to third parties. Royalties and profit share revenue are earned at the time the related product is sold by the licensee based on the terms of the specific licensing agreement and when the Company has no future obligations with respect to the royalty or profit share. The Company relies on financial information provided by licensees to estimate the amounts due to it under the related agreements. F-12 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 2. SIGNIFICANT ACCOUNTING POLICIES (Continued) Service and Other Service revenue attributable to the performance of contract services is recognized as the services are performed, under the proportionate performance method of revenue recognition. Performance is measured based on units-of-work performed relative to total units-of-work contracted. Units-of-work is generally measured based on hours spent. For clinical research services provided by the Company’s contract research division (‘‘CRD’’) prior to its disposal in July 2010 (as described in note 6), units-of-work was generally measured in terms of bed night stays, and for laboratory-testing services, units-of-work was generally measured in terms of numbers of samples analyzed. Research and Development Expenses Costs related to internal research and development programs, including costs associated with the development of acquired IPR&D, are expensed as goods are delivered or services are performed. Under certain research and development arrangements with third parties, the Company may be required to make payments that are contingent on the achievement of specific developmental, regulatory and/or commercial milestones. Before a product receives regulatory approval, milestone payments made to third parties are expensed when the milestone is achieved. Milestone payments made to third parties after regulatory approval is received are capitalized and amortized over the estimated useful life of the approved product. Amounts due from third parties as reimbursement of development activities conducted under certain research and development arrangements are recognized as a reduction of research and development expenses. Legal Costs Legal fees and other costs related to litigation and other legal proceedings are expensed as incurred and included in selling, general and administrative expenses. Legal costs expensed are reported net of expected insurance recoveries. A claim for insurance recovery is recognized when the claim becomes probable of realization. Advertising Costs Advertising costs comprise product samples, print media and promotional materials. Advertising costs related to new product launches are expensed on the first use of the advertisement. The Company did not have any deferred advertising costs recorded as of December 31, 2010 or 2009. Advertising costs expensed in 2010, 2009 and 2008 were $29.9 million, $10.0 million and $7.8 million, respectively. These costs are included in selling, general and administrative expenses. Share-Based Compensation The Company recognizes all share-based payments to employees, including grants of employee stock options and restricted share units (‘‘RSUs’’), at estimated fair value. The Company amortizes the fair value of stock option or RSU grants on a straight-line basis over the requisite service period of the individual stock option or RSU grant, which generally equals the vesting period. Stock option and RSU forfeitures are estimated at the time of grant and revised, if necessary, in subsequent periods if actual forfeitures differ from those estimates. The fair value of deferred share units (‘‘DSUs’’) granted to non-management directors is recognized as compensation expense at the grant date, and a DSU liability is recorded in accrued liabilities. The fair value of the DSU liability is remeasured at each reporting date, with a corresponding adjustment to compensation expense in the reporting period. Share-based compensation is recorded in cost of goods sold, research and development expenses, selling, general and administrative expenses and restructuring and other costs, as appropriate. Interest Expense Interest expense includes standby fees and the amortization of debt discounts and deferred financing costs. Interest costs are expensed as incurred, except to the extent such interest is related to construction in progress, in which case interest is capitalized. The Company did not capitalize any significant interest costs in 2010, 2009 or 2008. F-13 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 2. SIGNIFICANT ACCOUNTING POLICIES (Continued) Income Taxes Income taxes are accounted for under the liability method. Deferred tax assets and liabilities are recognized for the differences between the financial statement and income tax bases of assets and liabilities, and for operating losses and tax credit carryforwards. A valuation allowance is provided for the portion of deferred tax assets that is more likely than not to remain unrealized. Deferred tax assets and liabilities are measured using enacted tax rates and laws. The tax benefit from an uncertain tax position is recognized only if it is more likely than not that the tax position will be sustained upon examination by the appropriate taxing authority, based on the technical merits of the position. The tax benefits recognized from such a position are measured based on the amount that is greater than 50% likely of being realized upon settlement. Liabilities associated with uncertain tax positions are classified as long-term unless expected to be paid within one year. Interest and penalties related to uncertain tax positions, if any, are recorded in the provision for income taxes and classified with the related liability on the consolidated balance sheets. Earnings Per Share Basic earnings per share is calculated by dividing net income by the weighted-average number of common shares outstanding during the reporting period. Diluted earnings per share is calculated by dividing net income by the weighted-average number of common shares outstanding during the reporting period after giving effect to dilutive potential common shares for stock options, RSUs and convertible debt, determined using the treasury stock method. Comprehensive Income Comprehensive income comprises net income and other comprehensive income. Other comprehensive income comprises foreign currency translation adjustments, unrealized temporary holding gains or losses on available-for-sale investments, and the non-credit component of other-than-temporary losses on marketable debt securities. Accumulated other comprehensive income is recorded as a component of shareholders’ equity. Contingencies In the normal course of business, the Company is subject to loss contingencies, such as claims and assessments arising from litigation and other legal proceedings, contractual indemnities, product and environmental liabilities, and tax matters. Accruals for loss contingencies are recorded when the Company determines that it is both probable that a liability has been incurred and the amount of loss can be reasonably estimated. If the estimate of the amount of the loss is a range and some amount within the range appears to be a better estimate than any other amount within the range, that amount is accrued as a liability. If no amount within the range is a better estimate than any other amount, the minimum amount of the range is accrued as a liability. Reclassifications Certain prior year amounts have been reclassified to conform to the presentation adopted by the Company following the Merger. These reclassifications include the following: • accrued legal settlements have been reclassified to accrued liabilities; • provisions for chargebacks and distribution fees have been reclassified from accrued liabilities to a contra account netted against accounts receivable; • costs incurred by CRD in connection with contract research services provided to external customers have been reclassified from research and development expenses to cost of services; • amounts expensed as acquired IPR&D have been reclassified from research and development expenses to a separate line item; and • the loss on disposal of the Company’s corporate headquarters of $11.0 million recognized in 2009 has been reclassified from selling, general and administrative expenses to restructuring and other costs. F-14 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 2. SIGNIFICANT ACCOUNTING POLICIES (Continued) Adoption of New Accounting Standards Effective January 1, 2010, the Company adopted the following accounting standards: • Authoritative guidance requiring additional disclosure about the amounts of and reasons for significant transfers in and out of Level 1 and Level 2 fair value measurements. This guidance also clarifies existing disclosure requirements related to the level of disaggregation of fair value measurements for each class of assets and liabilities and disclosures about inputs and valuation techniques used to measure fair value for both recurring and nonrecurring Level 2 and Level 3 measurements. As the guidance only requires new disclosures, the adoption of this guidance did not impact the Company’s financial position or results of operations. In addition, effective for interim and annual periods beginning after December 15, 2010, this guidance will require additional disclosure and require an entity to present disaggregated information about activity in Level 3 fair value measurements on a gross basis. • Authoritative guidance for determining whether an entity is a variable interest entity (‘‘VIE’’). Under this guidance, an enterprise has a controlling financial interest when it has the power to direct the activities of a VIE that most significantly impact the entity’s economic performance, and the obligation to absorb losses of the entity or the right to receive benefits from the entity that could potentially be significant to the VIE. Upon adoption of this guidance, the Company determined that none of its existing collaboration and license arrangements with other entities for various products under development represented arrangements with VIEs. Accordingly, the adoption of this guidance did not have any impact on the Company’s consolidated financial statements. The Company will adopt the provisions of the following new accounting standards effective January 1, 2011: • Authoritative guidance clarifying how pharmaceutical manufacturers should recognize and classify in their income statements fees mandated by the U.S. Patient Protection and Affordable Care Act. The fees are imposed on manufacturers annually based on their share of the pharmaceutical industry’s branded drug sales for the preceding year. The portion allocated to an individual manufacturer becomes payable to the U.S. federal government once the manufacturer has a qualifying gross receipt from branded prescription drug sales. The guidance specifies that the liability for the fee should be estimated and recorded in full upon the first qualifying sale with a corresponding deferred cost that is amortized to expense using a straight-line method of allocation unless another method better allocates the fee over the calendar year in which it is payable. The annual fee should be presented as an operating expense. The guidance is effective for calendar years beginning after December 31, 2010, when the fee initially becomes effective. • Authoritative guidance recognizing the milestone method of revenue recognition as a valid application of the proportional performance model when applied to research and development arrangements. An entity may make an accounting policy election to recognize the receipt of a payment that is contingent upon the achievement of a substantive milestone in its entirety in the period in which the milestone is achieved. The guidance is effective for fiscal years, and interim periods within those years, beginning on or after June 15, 2010. As this guidance is consistent with the Company’s existing practice for recognizing milestone payments, it does not expect the adoption of this guidance to have a significant impact on its consolidated financial statements. • Authoritative guidance on multiple-element revenue arrangements, which requires an entity to allocate arrangement consideration at the inception of the arrangement to all of its deliverables based on relative selling prices. The guidance eliminates the use of the residual method of allocation and expands the ongoing disclosure requirements. The guidance is effective for the first fiscal year beginning after June 15, 2010, and may be adopted through prospective or retrospective application. The Company intends to adopt this guidance on a prospective basis. The Company is currently evaluating the effect that the adoption of this guidance will have on its consolidated financial statements. F-15 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 3. BIOVAIL MERGER WITH VALEANT Description of the Transaction On September 28, 2010, a wholly-owned subsidiary of Biovail acquired all of the outstanding equity of Valeant in a share transaction, in which each share of Valeant common stock was cancelled and converted into the right to receive 1.7809 Biovail common shares. The share consideration was valued at $26.35 per share based on the market price of Biovail’s common shares as of the Merger Date. In addition, immediately preceding the effective time of the Merger, Valeant paid its stockholders a special dividend of $16.77 per share (the ‘‘pre-Merger special dividend’’) of Valeant common stock. As a result of the Merger, Valeant became a wholly-owned subsidiary of Biovail. On December 22, 2010, the Company paid a post-Merger special dividend of $1.00 per common share (the ‘‘post-Merger special dividend’’). The post-Merger special dividend comprised aggregate cash paid of $297.6 million and 72,283 shares issued to shareholders that elected to reinvest in additional common shares of the Company through a special dividend reinvestment plan, which plan was terminated following payment of the post-Merger special dividend. Valeant is a multinational specialty pharmaceutical company that develops, manufactures and markets a broad range of pharmaceutical products. Valeant’s specialty pharmaceutical and over-the-counter (‘‘OTC’’) products are marketed under brand names and are sold in the U.S., Canada, Australia and New Zealand, where Valeant focuses most of its efforts on the dermatology and neurology therapeutic classes. Valeant also has branded generic and OTC operations in Europe and Latin America, which focus on pharmaceutical products that are bioequivalent to original products and are marketed under company brand names. Basis of Presentation The transaction has been accounted for as a business combination under the acquisition method of accounting, which requires, among other things, the share consideration transferred be measured at the acquisition date based on the then-current market price and that most assets acquired and liabilities assumed be recognized at their fair values as of the acquisition date. Acquisition-related transaction costs and certain acquisition-related restructuring charges are not included as a component of the acquisition accounting, but are accounted for as expenses in the periods in which the costs are incurred. Fair Value of Consideration Transferred The following table indicates the consideration transferred to effect the acquisition of Valeant: (Number of shares, stock options and restricted share units in thousands) Conversion Calculation Fair Value Form of Consideration Number of common shares of Biovail issued in exchange for Valeant common stock outstanding as of the Merger Date . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Multiplied by Biovail’s stock price as of the Merger Date(a) 139,137 $ 26.35 Number of common shares of Biovail expected to be issued pursuant to vested Valeant RSUs as a result of the Merger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Multiplied by Biovail’s stock price as of the Merger date(a) 1,694 $ 26.35 Fair value of vested and partially vested Valeant stock options converted into Biovail stock options . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Fair value of vested and partially vested Valeant RSUs converted into Biovail RSUs Cash consideration paid and payable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $3,666,245 Common shares 44,643 Common shares Stock options(b) 110,687 58,726 RSUs(c) Cash(d) 51,739 Total fair value of consideration transferred . . . . . . . . . . . . . . . . . . . . . . . . . . $3,932,040 (a) As the Merger was effective at 12:01 a.m. on September 28, 2010, the conversion calculation reflects the closing price of Biovail’s common shares on the New York Stock Exchange (‘‘NYSE’’) at September 27, 2010. (b) The fair value of the vested and partially vested portions of Valeant stock options that were converted into stock options of Biovail was recognized as a component of the consideration transferred, based on a weighted-average fair value of $17.63 per stock option, F-16 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 3. BIOVAIL MERGER WITH VALEANT (Continued) which was calculated using the Black-Scholes option pricing model. This calculation considered the closing price of Biovail’s common shares of $26.35 per share as of the Merger Date and the following assumptions: Expected volatility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Expected life . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Risk-free interest rate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Expected dividend yield . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32.9% 3.4 years 1.1% 1.5% The expected life of the options was determined by taking into account the contractual life of the options and estimated exercise pattern of the option holders. The expected volatility and risk-free interest rate were determined based on current market information, and the dividend yield was derived based on the expectation of the post-Merger special dividend of $1.00 per common share of the Company and no dividends thereafter. The fair values of the exchanged Biovail stock options exceeded the fair values of the vested and partially vested Valeant stock options as of the Merger Date in an amount of $17.2 million, which was recognized immediately as post-Merger compensation expense. (c) The fair value of the vested portion of Valeant time-based and performance-based RSUs converted into RSUs of Biovail was recognized as a component of the purchase price. The fair value of the vested portion of the Valeant time-based RSUs was determined based on the closing price of Biovail’s common shares of $26.35 per share as of the Merger Date. The fair value of Valeant performance-based RSUs was determined using a Monte Carlo simulation model, which utilizes multiple input variables to estimate the probability that the performance condition will be achieved. The fair value of the exchanged Biovail time-based RSUs exceeded the fair value of the vested and partially vested Valeant time-based RSUs as of the Merger Date in an amount of $3.8 million, which was recognized immediately as post-Merger compensation expense. (d) Cash consideration includes $39.7 million of income tax withholdings paid by the Company on behalf of employees of Valeant, in connection with the net share settlement of certain vested Valeant RSUs as of the Merger Date. In addition, under the terms of the Company’s employment agreement with J. Michael Pearson, Chief Executive Officer, cash equal to the pre-Merger special dividend payment will be paid to Mr. Pearson in respect of any of his 2008 performance awards that vest in February 2011 at the time of such vesting. As of the Merger Date, the aggregate amount of this cash payment in respect of the pre-Merger special dividend was estimated to be $13.7 million, based on the assumption that Mr. Pearson’s 2008 performance awards will vest at the maximum performance target. Of that amount, the portion attributable to Mr. Pearson’s pre-Merger service ($12.1 million) was recognized in the fair value of consideration transferred, while the portion attributable to Mr. Pearson’s post-Merger service ($1.6 million) is being recognized as share-based compensation expense over the remaining vesting period from the Merger Date to February 2011. Assets Acquired and Liabilities Assumed The following table summarizes the estimated fair values of the assets acquired and liabilities assumed as of the acquisition date. The following recognized amounts are provisional and subject to change: • amounts and useful lives for identifiable intangible assets, pending the finalization of valuation efforts; • amounts for income tax assets and liabilities, pending finalization of estimates and assumptions in respect of certain tax aspects of the transaction, and the filing of Valeant’s pre-Merger tax returns; and • allocation of goodwill among reporting units, pending the completion of the allocation of the consideration transferred to the assets acquired and liabilities assumed. The Company will finalize these amounts as it obtains the information necessary to complete the measurement process. Any changes resulting from facts and circumstances that existed as of the acquisition date may result in retrospective adjustments to the provisional F-17 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 3. BIOVAIL MERGER WITH VALEANT (Continued) amounts recognized at the acquisition date. These changes could be significant. The Company expects to finalize these amounts no later than one year from the acquisition date. Amounts Recognized as of Merger Date (as previously reported)(a) Measurement Period Adjustments(b) Amounts Recognized as of Merger Date (as adjusted) Cash and cash equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Accounts receivable(c) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Inventories(d) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other current assets(e) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Property, plant and equipment(f) . . . . . . . . . . . . . . . . . . . . . . . . . . Identifiable intangible assets, excluding in-process research and development(g) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . In-process research and development(h) . . . . . . . . . . . . . . . . . . . . . . Other non-current assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Current liabilities(i) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Long-term debt, including current portion(j) . . . . . . . . . . . . . . . . . . . Deferred income taxes, net(k) . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other non-current liabilities(l) . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 348,637 194,930 208,874 33,460 184,757 3,844,310 1,399,956 5,905 (384,223) (2,913,614) (1,472,321) (140,397) Total indentifiable net assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,310,274 Equity component of 4.0% Convertible Notes(j) . . . . . . . . . . . . . . . . Call option agreements(m) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Goodwill(n) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (225,971) (28,000) 2,863,653 Total fair value of consideration transferred . . . . . . . . . . . . . . . . . . . $ 3,919,956 — — — (2,591) — — 5,000 203 (1,351) — 4,530 (8,910) (3,119) — — 15,203 $12,084 $ 348,637 194,930 208,874 30,869 184,757 3,844,310 1,404,956 6,108 (385,574) (2,913,614) (1,467,791) (149,307) 1,307,155 (225,971) (28,000) 2,878,856 $ 3,932,040 (a) As previously reported in the Company’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2010. (b) The measurement period adjustments primarily reflect: (i) an increase in the total fair value of consideration transferred to recognize the estimated cash payment in respect of the pre-Merger special dividend on Mr. Pearson’s 2008 performance awards (as described above under ‘‘Fair Value of Consideration Transferred’’); (ii) a change in the fair value of acquired IPR&D assets related to the value ascribed to taribarivin (as described in note 4); and (iii) the tax impact of pre-tax measurement period adjustments. The measurement period adjustments were made to reflect facts and circumstances existing as of the Merger Date, and did not result from intervening events subsequent to the Merger Date. These adjustments did not have a significant impact on the Company’s previously reported consolidated financial statements for the quarter ended September 30, 2010 and, therefore, the Company has not retrospectively adjusted those financial statements. (c) The fair value of accounts receivable acquired was $194.9 million, which comprised trade receivables ($151.9 million) and royalty and other receivables ($43.1 million). The gross contractual amount of trade receivables was $159.0 million, of which the Company expects that $7.1 million will be uncollectible. (d) Includes $72.1 million to record Valeant’s inventory at its estimated fair value. (e) Includes prepaid expenses and assets held for sale. F-18 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 3. BIOVAIL MERGER WITH VALEANT (Continued) (f) The following table summarizes the amounts and useful lives assigned to property, plant and equipment: Land . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Buildings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Machinery and equipment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other equipment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Leasehold improvements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Construction in progress . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Total property, plant and equipment acquired . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Useful Lives (Years) NA Up to 40 3-20 3-10 Term of lease NA Amounts Recognized as of Merger Date $ 23,248 75,008 64,516 11,003 3,728 7,254 $184,757 (g) The following table summarizes the provisional amounts and useful lives assigned to identifiable intangible assets: Weighted- Average Useful Lives (Years) Amounts Recognized as of Merger Date Product brands . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Corporate brands . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Product rights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Out-licensed technology and other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Total identifiable intangible assets acquired . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 20 9 7 15 $3,114,689 168,602 360,970 200,049 $3,844,310 (h) Acquired IPR&D assets are initially recognized at fair value and are classified as indefinite-lived intangible assets until the successful completion or abandonment of the associated research and development efforts. The significant components of the acquired IPR&D assets relate to the development of ezogabine/retigabine in collaboration with Glaxo Group Limited, a subsidiary of GlaxoSmithKline plc (the entities within The Glaxo Group of Companies are referred throughout as ‘‘GSK’’), as an adjunctive treatment for refractory partial-onset seizures in adult patients with epilepsy (as described in note 5), and a number of dermatology products in development for the treatment of severe acne and fungal infections, among other indications. The following table summarizes the provisional amounts assigned to the acquired IPR&D assets: Amounts Recognized as of Merger Date Ezogabine/retigabine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Dermatology products . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 891,461 431,323 82,172 Total IPR&D assets acquired . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $1,404,956 A multi-period excess earnings methodology (income approach) was used to determine the estimated fair values of the acquired IPR&D assets. The projected cash flows from these assets were adjusted for the probabilities of successful development and commercialization of each project. A risk-adjusted discount rate of 9% was used to present value the projected cash flows. (i) Includes accounts payable, accrued liabilities and income taxes payable. (j) As described in note 14, in connection with the Merger, Valeant secured financing of $125.0 million under a senior secured revolving credit facility (the ‘‘Revolving Credit Facility’’), $1.0 billion under a senior secured term loan A facility (the ‘‘Term Loan F-19 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 3. BIOVAIL MERGER WITH VALEANT (Continued) A Facility’’), and $1.625 billion under a senior secured term loan B facility (the ‘‘Term Loan B Facility’’), and used a portion of the proceeds to undertake the following transactions prior to the Merger Date: • fund the payment of the pre-Merger special dividend; • fund the legal defeasance of Valeant’s existing 8.375% and 7.625% senior unsecured notes, by depositing with the trustees amounts sufficient to pay 100% of the outstanding aggregate principal amount of the notes, plus applicable premium and accrued and unpaid interest, on October 27, 2010; and • fund the repayment in full of indebtedness under Valeant’s existing senior secured term loan. Concurrent with the closing of the Merger, Valeant issued $500.0 million aggregate principal amount of 6.75% senior notes due 2017 (the ‘‘2017 Notes’’) and $700.0 million aggregate principal amount of 7.00% senior notes due 2020 (the ‘‘2020 Notes’’). A portion of the proceeds of the 2017 Notes and 2020 Notes offering was used to pay down $1.0 billion of the Term Loan B Facility. Valeant incurred $118.4 million of debt issuance costs in connection with the above financings that were ascribed a fair value of nil in the acquisition accounting. In addition, as of the Merger Date, Valeant had $225.0 million outstanding principal amount of 4.0% convertible subordinated notes due 2013 (the ‘‘4.0% Convertible Notes’’). The Company is required to separately account for the liability component and equity component of the 4.0% Convertible Notes, as these notes have cash settlement features. The fair value of the 4.0% Convertible Notes was determined to be $446.5 million. A fair value of $220.5 million has been allocated to the liability component in a manner reflecting the Company’s interest rate for a similar debt instrument without a conversion feature. The residual of the fair value of $226.0 million represents the carrying amount of the equity component, which was recorded as additional paid-in capital in the Company’s consolidated shareholders’ equity. The following table summarizes the fair value of long-term debt assumed as of the Merger Date: Amounts Recognized as of Merger Date Term Loan A Facility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Term Loan B Facility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2017 Notes 2020 Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4.0% Convertible Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $1,000,000 500,000 497,500 695,625 220,489 Total long-term debt assumed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $2,913,614 (k) Comprises current deferred tax assets ($68.9 million), non-current deferred tax assets ($4.3 million), current deferred tax liabilities ($6.8 million) and non-current deferred tax liabilities ($1,534.3 million). (l) Includes the fair value of contingent consideration related to Valeant’s acquisition of Princeton Pharma Holdings LLC, and its wholly-owned operating subsidiary, Aton Pharma, Inc. (‘‘Aton’’), on May 26, 2010. The aggregate fair value of the contingent consideration was determined to be $21.6 million as of the Merger Date. The contingent consideration consists of future milestones predominantly based upon the achievement of approval and commercial targets for certain pipeline products (which are included in the fair value ascribed to the IPR&D assets acquired, as described above under (h)). The range of the undiscounted amounts the Company could be obligated to pay as contingent consideration ranges from nil to $390.0 million. (m) The Company assumed Valeant’s existing call option agreements in respect of the shares underlying the conversion of $200.0 million principal amount of the 4.0% Convertible Notes. These agreements consist of purchased call options on 15,218,960 common shares of the Company, which mature on May 20, 2011, and written call options on the identical number of shares, which mature on August 18, 2011. These agreements are expected to reduce the potential dilution from conversion of the 4.0% Convertible Notes. In addition, the Company assumed written call option agreements in respect of 3,863,670 common shares of the Company underlying Valeant’s 3.0% convertible subordinated notes that matured in August 2010. The written call options on shares underlying the 3.0% convertible subordinated notes expired on November 15, 2010, and were settled over the following 30 business days. On November 19, 2010, the call option agreements were amended to require cash settlement, resulting in the reclassification F-20 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 3. BIOVAIL MERGER WITH VALEANT (Continued) of the $32.8 million fair value of the written call options as a liability as of that date. The Company recognized a loss of $10.1 million on the written call options settled for cash, which has been included in loss on extinguishment of debt (as described in note 19). (n) Goodwill is calculated as the difference between the Merger Date fair value of the consideration transferred and the provisional values assigned to the assets acquired and liabilities assumed. None of the goodwill is expected to be deductible for tax purposes. The goodwill recorded represents the following: • cost savings, operating synergies and other benefits expected to result from combining the operations of Valeant with those of Biovail; • the value of the going-concern element of Valeant’s existing business (that is, the higher rate of return on the assembled net assets versus if Biovail had acquired all of the net assets separately); and • intangible assets that do not qualify for separate recognition (for instance, Valeant’s assembled workforce), as well as future, as yet unidentified research and development projects. The provisional amount of goodwill by business segment is indicated in note 12. Acquisition-Related Costs The Company has incurred to date $38.3 million of transaction costs directly related to the Merger, which includes expenditures for advisory, legal, valuation, accounting and other similar services. These costs have been expensed as acquisition-related costs. Actual and Pro Forma Impact of Merger The revenues of Valeant for the period from the Merger Date to December 31, 2010 were $274.6 million and earnings were $5.8 million, excluding the effects of the acquisition accounting adjustments described above and including interest costs related to debt issued in connection with the Merger. The following table presents unaudited pro forma consolidated results of operations for the years ended December 31, 2010 and 2009, as if the transaction had occurred as of January 1, 2009: 2010 2009 Revenues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Net income (loss) $1,928,034 (55,316) $1,650,891 57,730 The unaudited pro forma consolidated results of operations, presented in the table above, reflect the refinement of the useful lives of identifiable intangible assets, the impact of measurement period and other adjustments, as well as related tax impacts, identified in the fourth quarter of 2010 and, therefore, may not be comparable to unaudited pro forma financial information related to the Merger as previously reported by the Company. The unaudited pro forma consolidated results of operations were prepared using the acquisition method of accounting and are based on the historical financial information of Biovail and Valeant. The unaudited pro forma information does not reflect any cost savings, operating synergies and other benefits that the Company may achieve as a result of the Merger, or the costs necessary to achieve these cost savings, operating synergies and other benefits. In addition, the unaudited pro forma information does not reflect the costs to integrate the operations of Biovail and Valeant. The unaudited pro forma information is not necessarily indicative of what the Company’s consolidated results of operations actually would have been had the transaction been completed on January 1, 2009. In addition, the unaudited pro forma information does not purport to project the future results of operations of the Company. The unaudited pro forma information reflects primarily the following unaudited pro forma adjustments: • elimination of Valeant’s historical intangible asset amortization expense; • additional amortization expense related to the provisional fair value of identifiable intangible assets acquired; • additional depreciation expense related to the fair value adjustment to property, plant and equipment acquired; F-21 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 3. BIOVAIL MERGER WITH VALEANT (Continued) • elimination of interest expense related to Valeant’s legacy 8.375% and 7.625% senior unsecured notes and senior secured term loan that were repaid as part of the Merger transaction; • additional interest expense associated with the Term Loan A Facility, Term Loan B Facility and 2017 Notes and 2020 Notes financing obtained by Valeant in connection with the Merger; • reduced non-cash interest expense related to the accretion of the principal amount of the 4.0% Convertible Notes as a result of the fair value adjustment; • elimination of the amortization of deferred financing costs recorded by Biovail related to its senior secured credit facility, which was terminated in connection with the Merger (as described in note 14); • additional share-based compensation expense related to unvested stock options and RSUs issued by Biovail to replace Valeant’s stock options and RSUs; • elimination of acquisition-related costs and Merger-related restructuring charges, which will not have a continuing impact on the Company’s operations; and • elimination of $53.3 million of the acquisition accounting adjustment on Valeant’s inventory that was sold subsequent to the Merger Date, which will not have a continuing impact on the Company’s operations. In addition, all of the above adjustments were adjusted for the applicable tax impact. A combined U.S. federal and state estimated tax rate of 38% has been used in accordance with Valeant’s intention to repatriate to the U.S. the earnings of non-U.S. subsidiaries owned by the U.S. corporation. 4. ACQUISITIONS Ribavirin On November 1, 2010, the Company paid Kadmon Pharmaceuticals LLC (‘‘Kadmon’’) $7.5 million for exclusive rights to certain dosage forms of ribavirin in Poland, Hungary, the Czech Republic, Slovakia, Romania and Bulgaria. Ribavirin is indicated for the treatment of viral diseases, including hepatitis C virus. The total purchase price has been capitalized as a product right intangible asset with an estimated useful life of 10 years. Under a separate agreement dated November 1, 2010, the Company granted Kadmon an exclusive, worldwide license to taribavirin, excluding the territory of Japan, in exchange for an upfront payment of $5.0 million, other development milestones, and royalty payments in the range of 8-12% of future net sales. The fair value associated with taribarivin was included in the acquired IPR&D assets identified as of the Merger Date. Hamilton Brands On October 29, 2010, the Company acquired the intellectual property, trademarks and inventory related to the Hamilton skin care brand in Australia for cash consideration of $14.7 million. The purchase price was allocated to the trademark intangible asset ($11.7 million) and inventory ($3.0 million). The useful life of the trademark intangible asset was estimated to be 10 years. Istradefylline On June 2, 2010, the Company entered into a license agreement with Kyowa Hakko Kirin Co., Ltd. (‘‘Kyowa Hakko Kirin’’) to acquire the U.S. and Canadian rights to develop and commercialize products containing istradefylline — a new chemical entity targeted for the treatment of Parkinson’s disease. Under the terms of the license agreement, the Company paid an upfront fee of $10.0 million, and the Company could pay up to $20.0 million in potential development milestones through U.S. Food and Drug Administration (‘‘FDA’’) approval and up to an additional $35.0 million if certain sales-based milestones are met. The Company will also make tiered royalty payments of up to 30% on net commercial sales of products containing istradefylline. In connection with this acquisition, the Company also entered into an agreement with Kyowa Hakko Kirin for the supply of the istradefylline compound. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, the $10.0 million upfront payment, together with $0.2 million of acquisition costs, was charged to acquired IPR&D expense in the second quarter of 2010. F-22 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 4. ACQUISITIONS (Continued) AMPAKINE(cid:4) On March 25, 2010, the Company acquired certain AMPAKINE(cid:4) compounds, including associated intellectual property, from Cortex Pharmaceuticals, Inc. (‘‘Cortex’’) for use in the field of respiratory depression, a brain-mediated breathing disorder. The acquired compounds include the Phase 2 compound CX717 in an oral formulation, the pre-clinical compounds CX1763 and CX1942, and the injectable dosage form of CX1739. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, upfront payments totaling $10.0 million made by the Company to Cortex, together with $0.7 million of acquisition costs, were charged to acquired IPR&D expense in the first quarter of 2010. As described in note 6, the Company has suspended development of the AMPAKINE(cid:4) compounds and is reviewing its options with Cortex. Staccato(cid:4) Loxapine On February 9, 2010, the Company entered into a collaboration and license agreement with Alexza Pharmaceuticals, Inc. (‘‘Alexza’’) to acquire the U.S. and Canadian development and commercialization rights to AZ-004 for the treatment of psychiatric and/or neurological indications and the symptoms associated with these indications, including the initial indication of treating agitation in schizophrenia and bipolar patients. AZ-004 combines Alexza’s proprietary Staccato(cid:4) drug-delivery system with the antipsychotic drug loxapine. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, the $40.0 million upfront payment made by the Company to Alexza, together with $0.3 million of acquisition costs, was charged to acquired IPR&D expense in the first quarter of 2010. On October 8, 2010, Alexza received a Complete Response Letter from the FDA regarding the New Drug Application (‘‘NDA’’) for AZ-004, in which the FDA indicated that the NDA was not ready for approval. As described in note 6, the Company has terminated the collaboration and license agreement with Alexza. GDNF On December 21, 2009, the Company entered into a license agreement with Amgen Inc. (‘‘Amgen’’) and MedGenesis Therapeutix Inc. (‘‘MedGenesis’’), pursuant to which the Company was granted a license to exploit GDNF in certain central nervous system (‘‘CNS’’) indications in certain countries (including the U.S., Canada, Japan, and a number of European countries). At the same time, the Company entered into a collaboration agreement with MedGenesis to develop and commercialize GDNF, initially for the treatment of Parkinson’s disease in the U.S., Japan and certain European countries and, potentially, in other countries and other CNS indications. Pursuant to the collaboration agreement, the Company was granted a license to MedGenesis’s Convection Enhanced Delivery platform for use with GDNF in CNS indications. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, the $6.0 million upfront payment made by the Company to MedGenesis, together with acquisition costs of $2.9 million, was charged to acquired IPR&D expense in the fourth quarter of 2009. As described in note 6, the Company has terminated the license agreement with Amgen and MedGenesis and the collaboration agreement with MedGenesis. Fipamezole On August 24, 2009, the Company entered into a collaboration and license agreement with Santhera Pharmaceuticals (Switzerland) Ltd. (‘‘Santhera’’), a subsidiary of Santhera Pharmaceuticals Holding AG, to acquire the U.S. and Canadian rights to develop, manufacture and commercialize fipamezole for the treatment of a number of neurological and psychiatric conditions, including levodopa-induced dyskinesia, also known as Parkinson’s disease dyskinesia. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, upfront payments totaling $12.0 million made by the Company to Santhera, together with acquisition costs of $0.1 million, were charged to acquired IPR&D expense in the third and fourth quarters of 2009. As described in note 6, the Company has terminated the collaboration and license agreement with Santhera. Tetrabenazine On June 19, 2009, the Company acquired the worldwide development and commercialization rights to the entire portfolio of tetrabenazine products, including Xenazine(cid:4) and Nitoman(cid:4), held by Cambridge Laboratories (Ireland) Limited and its affiliates (‘‘Cambridge’’). As described below, the Company had previously obtained certain licensing rights to tetrabenazine in the U.S. and Canada through the acquisition of Prestwick Pharmaceuticals, Inc. (‘‘Prestwick’’) in September 2008. By means of this acquisition, the F-23 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 4. ACQUISITIONS (Continued) Company obtained Cambridge’s economic interest in the supply of tetrabenazine for the U.S. and Canadian markets, as well as for a number of other countries in Europe and around the world through existing distribution arrangements. In addition, the Company assumed Cambridge’s royalty obligations to third parties on the worldwide sales of tetrabenazine. This acquisition was accounted for as a business combination under the acquisition method of accounting. The total purchase price comprised cash consideration of $200.0 million paid on closing, and additional payments of $12.5 million and $17.5 million due to Cambridge on the first and second anniversaries of the closing date, respectively. The second payment is subject to a right of set-off against amounts for which the Company has a claim against Cambridge. These additional payments were fair valued at $26.8 million, using an imputed interest rate comparable to the Company’s available borrowing rate at the date of acquisition, and were recorded in long-term debt (as described in note 14). No gain or loss was recognized in conjunction with the effective settlement of the contractual relationship between Prestwick and Cambridge as a result of this acquisition, as the pre-existing contracts could have been terminated without financial penalty. The Company incurred $5.6 million of costs related to this acquisition, which were expensed as acquisition- related costs in the second quarter of 2009. The following table summarizes the estimated fair values of the assets acquired at the acquisition date: Inventory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Intangible assets: $ 1,068 Product rights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Acquired IPR&D . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189,700 36,000 Assets acquired . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $226,768 The fair value of the currently marketed immediate-release tetrabenazine products was allocated to the product rights intangible asset, with an estimated useful life of approximately nine years. The projected cash flows from the products were adjusted for the probabilities of genericization and competition from the IPR&D projects described below. The acquired IPR&D assets related to a modified-release formulation of tetrabenazine under development initially for the treatment of Tourette’s Syndrome (BVF-018) and an isomer of tetrabenazine (RUS-350). A multi-period excess earnings methodology (income approach) was used to determine the estimated fair values of the acquired IPR&D assets. The projected cash flows from these assets were adjusted for the probabilities of successful development and commercialization of each project. A risk-adjusted discount rate of 20% was used to present value the projected cash flows. The fair values assigned to BVF-018 and RUS-350 were $28.0 million and $8.0 million, respectively. Based on the results of development efforts completed subsequent to the acquisition date, the Company decided to terminate the RUS-350 project in 2009, having determined that the isomer was unlikely to provide meaningful benefits to patients beyond that provided by tetrabenazine, and recorded a charge of $8.0 million to write off the related asset to acquired IPR&D expense. In addition, as described in note 6, the Company terminated the development of BVF-018 in 2010, and recorded a charge of $28.0 million to write off the related asset to acquired IPR&D expense. Wellbutrin XL(cid:4) On May 14, 2009, the Company acquired the full U.S. commercialization rights to Wellbutrin XL(cid:4) from GSK. The Company had supplied Wellbutrin XL(cid:4) to GSK for marketing or distribution in the U.S. since September 2003. The Wellbutrin XL(cid:4) product formulation was developed and is manufactured by the Company under its own patents and proprietary technology. Pursuant to the terms of the asset purchase agreement, the Company paid $510.0 million to GSK to acquire the U.S. NDA for Wellbutrin XL(cid:4). Pursuant to the terms of a trademark and license agreement with GSK, the Company also obtained an exclusive, royalty-free license to the Wellbutrin XL(cid:4) trademark for use in the U.S. This acquisition was accounted for as a purchase of identifiable intangible assets. Accordingly, the total purchase price (including costs of acquisition of $0.5 million) was allocated to the trademark intangible asset, with an estimated useful life of 10 years. In addition, the Company acquired the Wellbutrin XL(cid:4) finished goods inventory owned by GSK valued at $10.5 million. Pimavanserin On May 1, 2009, the Company entered into a collaboration and license agreement with ACADIA Pharmaceuticals Inc. (‘‘ACADIA’’) to acquire the U.S. and Canadian rights to develop, manufacture and commercialize pimavanserin in a number of neurological and psychiatric conditions, including Parkinson’s disease psychosis, Alzheimer’s disease psychosis and, as an adjunctive therapy, to treat schizophrenia. This acquisition was accounted for as a purchase of IPR&D assets with no alternative future use. Accordingly, the F-24 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 4. ACQUISITIONS (Continued) $30.0 million upfront payment made by the Company to ACADIA, together with acquisition costs of $0.4 million, was charged to acquired IPR&D expense in the second quarter of 2009. As described in note 6, the Company has terminated the collaboration and license agreement with ACADIA. Prestwick On September 16, 2008, the Company acquired 100% of Prestwick, which was accounted for as a business combination under the former purchase method of accounting. Accordingly, the results of Prestwick’s operations have been included in the Company’s consolidated financial statements since September 16, 2008. Prestwick had acquired the licensing rights to Xenazine(cid:4) in the U.S. and Nitoman(cid:4) in Canada from Cambridge, which, at the time, held the worldwide license for tetrabenazine. On August 15, 2008, an NDA for Xenazine(cid:4) received FDA approval for the treatment of chorea associated with Huntington’s disease and was granted orphan drug designation by the FDA, which provides the product with seven years of market exclusivity in the U.S. from the date of FDA approval. Nitoman(cid:4) has been available in Canada since 1996, where it is approved for the treatment of hyperkinetic movement disorders including Huntington’s chorea. Prior to the Company’s acquisition of Prestwick, Prestwick entered into an exclusive supply and distribution agreement with Lundbeck Inc. (a subsidiary of H. Lundbeck A/S) (‘‘Lundbeck’’), formerly known as Ovation Pharmaceuticals, Inc. (‘‘Ovation’’), for Xenazine(cid:4) in the U.S. Ovation paid Prestwick $50.0 million for the exclusive rights to market and distribute Xenazine(cid:4) for an initial term of 15 years. The Company supplies Xenazine(cid:4) product to Lundbeck for a variable percentage of Lundbeck’s annual net sales of the product. For annual net sales up to $125 million, the Company’s supply price equals 72% of net sales. Beyond $125 million, the Company’s supply price equals 65% of net sales. Prior to the acquisition of the worldwide development and commercialization rights to tetrabenazine (as described above), the Company acquired Xenazine(cid:4) product from Cambridge at a supply price of 50% of Lundbeck’s net sales. The total purchase price, including acquisition costs of $3.4 million, less cash acquired of $1.1 million, was $101.9 million. The following table summarizes the estimated fair values of the assets acquired and liabilities assumed at the date of acquisition: Current assets (excluding cash acquired) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Intangible assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Current liabilities (excluding deferred revenue) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Deferred revenue: $ 2,166 157,862 (8,108) Current . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Long-term . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (3,000) (47,000) Net assets acquired . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $101,920 The identifiable intangible assets are associated with the acquired Xenazine(cid:4) and Nitoman(cid:4) product rights, and have an estimated useful life of 10 years. The deferred revenue liability recognized at the date of acquisition represents a performance obligation assumed by the Company to supply Xenazine(cid:4) to Lundbeck over the 15-year term of the supply and distribution agreement. At the date of acquisition, Prestwick had a number of other CNS products in early-stage development, including Lisuride Sub Q (advanced Parkinson’s disease), Lisuride Patch (Parkinson’s disease), and D-Serine (schizophrenia). The Company does not intend to pursue the development of those products based on its assessment of their technical feasibility and/or commercial viability. In addition, Prestwick obtained options from Cambridge to participate in the development of future tetrabenazine products. As of the date of acquisition, Prestwick had not undertaken any development efforts related to those tetrabenazine products. As a result, no amount was allocated to any of these products in the purchase price allocation. 5. COLLABORATION AGREEMENT In October 2008, Valeant closed the worldwide License and Collaboration Agreement (the ‘‘Collaboration Agreement’’) with GSK to develop and commercialize a first-in-class neuronal potassium channel opener for treatment of adult epilepsy patients with refractory partial onset seizures and its backup compounds, whose generic name will be ezogabine in the U.S. and retigabine in all other countries. Pursuant to the terms of the Collaboration Agreement, Valeant granted co-development rights and worldwide commercialization rights to GSK. Valeant agreed to share equally with GSK the development and pre-commercialization expenses of ezogabine/retigabine in the U.S., Australia, New Zealand, Canada and Puerto Rico (the ‘‘Collaboration Territory’’). Following the launch of an ezogabine/retigabine F-25 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 5. COLLABORATION AGREEMENT (Continued) product, the Company will share equally in the profits of ezogabine/retigabine in the Collaboration Territory. In addition, Valeant granted GSK an exclusive license to develop and commercialize retigabine in countries outside of the Collaboration Territory and certain backup compounds to ezogabine/retigabine worldwide. GSK is responsible for all expenses outside of the Collaboration Territory and will solely fund the development of any backup compound. The Company will receive up to a 20% royalty on net sales of retigabine outside of the Collaboration Territory. In addition, if backup compounds are developed and commercialized by GSK, GSK will pay the Company royalties of up to 20% of net sales of products based upon such backup compounds. GSK has the right to terminate the Collaboration Agreement at any time prior to the receipt of the approval by the FDA of an NDA for an ezogabine product, which right may be irrevocably waived at any time by GSK. Unless otherwise terminated, the Collaboration Agreement will continue on a country-by-country basis until GSK has no remaining payment obligations with respect to such country. Under the terms of the Collaboration Agreement, GSK will pay the Company up to $545.0 million based upon the achievement of certain regulatory, commercialization and sales milestones, and the development of additional indications for ezogabine/retigabine. GSK will also pay the Company up to an additional $150.0 million if certain regulatory and commercialization milestones are achieved for backup compounds to ezogabine/retigabine. The Company’s rights to ezogabine/retigabine are subject to an asset purchase agreement between Meda Pharma GmbH & Co. KG (‘‘Meda Pharma’’) and Xcel Pharmaceuticals, Inc., which was acquired by Valeant in 2005 (the ‘‘Meda Pharma Agreement’’). Under the Meda Pharma Agreement, the Company may be required to make certain milestone and royalty payments to Meda Pharma. Within the Collaboration Territory, any royalties to Meda Pharma will be shared by the Company and GSK. In the rest of the world, the Company will be responsible for the payment of these royalties to Meda Pharma from the royalty payments it receives from GSK. The Company’s interest in ezogabine/retigabine was recorded at a fair value of $891.5 million as of the Merger Date (as described in note 3). 6. RESTRUCTURING AND INTEGRATION Merger-Related Cost-Rationalization and Integration Initiatives The Company has initiated measures to integrate the operations of Biovail and Valeant, capture operating synergies and generate cost savings across the Company. These measures include: • workforce reductions across the Company and other organizational changes; • closing of duplicative facilities and other site rationalization actions company-wide, including research and development facilities, sales offices and corporate facilities; • leveraging research and development spend; • increased use of shared services; and • procurement savings. The Company estimates that it will incur costs between $135 million and $180 million (of which the non-cash component, including share-based compensation, is expected to be approximately $55 million) in connection with these cost-rationalization and integration initiatives. These costs include employee termination costs (including related share-based payments), costs to consolidate or close facilities and relocate employees, asset impairments, and contract termination and lease cancellation costs. The following costs were incurred in connection with these initiatives through December 31, 2010: Employee Termination Costs Severance and Related Benefits Share-Based Compensation IPR&D Termination Costs(1) Contract Termination, Facility Closure and Other Costs Costs incurred and charged to expense . . . Cash payments . . . . . . . . . . . . . . . . . . Non-cash adjustments . . . . . . . . . . . . . . $ 58,727 (33,938) — $ 49,482 — (49,482) Balance, December 31, 2010 . . . . . . . . . $ 24,789 $ — $ 13,750 (13,750) — $ — $12,862 (8,755) (2,437) $ 1,670 (1) As described below under ‘‘— Research and Development Pipeline Rationalization’’. Total $134,821 (56,443) (51,919) $ 26,459 F-26 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 6. RESTRUCTURING AND INTEGRATION (Continued) As described in note 26, restructuring costs are not recorded in the Company’s business segments. Employee Termination Costs The Company recognized employee termination costs of $58.7 million for severance and related benefits payable to approximately 500 employees of Biovail and Valeant who have been, or will be, terminated as a result of the Merger. These reductions primarily reflect the elimination of redundancies and consolidation of staff in the research and development, general and administrative, and sales and marketing functions. As of December 31, 2010, $33.9 million of the termination costs had been paid, and the Company expects that a significant portion of the remaining costs will be paid prior to April 1, 2011, with the balance payable through to the first quarter of 2012. In addition, the Company recognized incremental share-based compensation expense of $49.5 million, related to the following stock options and RSUs held by terminated employees of Biovail and Valeant: Stock options and time-based RSUs held by Biovail employees with employment agreements . . . . . . . . . . . . . . . . . . Stock options held by Biovail employees without employment agreements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Performance-based RSUs held by Biovail executive officers and selected employees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Stock options and RSUs held by former executive officers of Valeant $ 9,622 (492) 20,287 20,065 $49,482 Research and Development Pipeline Rationalization Prior to the Merger, the Company’s product development and business development efforts were focused on unmet medical needs in specialty CNS disorders. Since the Merger, the Company has been employing a leveraged research and development model that allows it to progress development programs, while minimizing research and development expense, through partnerships and other means. In consideration of this model, following the Merger, the Company conducted a strategic and financial review of its product development pipeline and identified the programs that did not align with the Company’s new research and development model. These programs are outlined in the table below. In respect of the Staccato(cid:4) loxapine, GDNF, tetrabenazine, fipamezole and pimavanserin programs, the Company provided notices of termination to, or entered into termination agreements with, the counterparties to the agreements. Regarding the AMPAKINE(cid:4) program, the Company has suspended development of these compounds and is reviewing its options with Cortex and other potential parties. Program Counterparty Compound Contingent Milestone Obligations Terminated(1) IPR&D Termination Charges AZ-004 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Alexza Cortex BVF-007 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BVF-014 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . MedGenesis LifeHealth Limited BVF-018 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BVF-025 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Santhera BVF-036,-040, -048 . . . . . . . . . . . . . . . . . . . . . . ACADIA Staccato(cid:4) loxapine AMPAKINE(cid:4) GDNF Tetrabenazine Fipamezole Pimavanserin $ 90,000 $ 15,000 $ 20,000 Nil $200,000 $365,000 Nil Nil $ 5,000(2) $28,000(3) Nil $ 8,750(2) (1) Represents the maximum amount of previously disclosed milestone payments the Company could have been required to make to the counterparty under each agreement. These milestone payments were contingent on the achievement of specific developmental, regulatory and commercial milestones. In addition, the Company could have been obligated to make royalty payments based on future net sales of the products if regulatory approval was obtained. As a consequence of the termination of these arrangements, the Company has no ongoing or future obligation in respect of these milestone or royalty payments. (2) Represents the amount of negotiated settlements with each counterparty that was recognized and paid by the Company in the three-month period ended December 31, 2010. (3) Represents the carrying amount of the related acquired IPR&D asset capitalized in connection with the tetrabenazine acquisition in June 2009 (as described in note 4). F-27 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 6. RESTRUCTURING AND INTEGRATION (Continued) In addition to the settlement payments identified in the table above, the Company has incurred internal and external costs of $5.3 million in the fourth quarter of 2010 that were directly associated with the fulfillment of its remaining contractual obligations under these terminated arrangements, which costs have been recognized as restructuring costs. Following the completion of these activities, the Company intends to vacate its remaining research and development facility in Chantilly, Virginia, and, as a result, the Company recognized $3.0 million of accelerated depreciation arising from the reduced useful life of the equipment and leasehold improvements located at this facility. Pre-Merger Cost-Rationalization Initiatives In May 2008, the Company initiated restructuring measures that were intended to rationalize its manufacturing operations, pharmaceutical sciences operations, and general and administrative expenses. The following costs were incurred in connection with these initiatives through December 31, 2010: Asset Impairments Employee Termination Costs Contract Termination, Facility Manufacturing Pharmaceutical Sciences Corporate Manufacturing Pharmaceutical Closure and Other Costs Sciences Total $ — $ — $ — $ — $ — $ — $ — Balance, January 1, 2008 . . . Costs incurred and charged to expense . . . . . . . . . . Cash payments . . . . . . . . . . . . . Non-cash adjustments 42,602 — (42,602) Balance, December 31, 2008 — Costs incurred and charged to expense . . . . . . . . . . Cash payments . . . . . . . . . . . . . Non-cash adjustments 7,591 — (7,591) Balance, December 31, 2009 — Costs incurred and charged to expense . . . . . . . . . . Cash payments . . . . . . . . . . . . . Non-cash adjustments 400 — (400) 16,702 — (16,702) — 2,784 — (2,784) — — — — — — — — 10,968 — (10,968) — — — — 3,309 — — 3,309 4,942 (2,041) — 6,210 1,330 (7,540) — 2,724 (2,724) — — 1,441 (1,278) 71 234 1,924 (2,057) (101) 4,865 (333) (1,186) 3,346 2,307 (1,321) — 4,332 2,365 (3,017) — 70,202 (3,057) (60,490) 6,655 30,033 (4,640) (21,272) 10,776 6,019 (12,614) (501) Balance, December 31, 2010 $ — $ — $ — $ — $ — $ 3,680 $ 3,680 Manufacturing Operations On January 15, 2010, the Company completed the sale of its Dorado, Puerto Rico manufacturing facility for net cash proceeds of $8.5 million. The related property, plant and equipment was classified as assets held for sale on the consolidated balance sheet as of December 31, 2009. The Company occupied the Dorado facility until March 31, 2010, pursuant to a short-term lease agreement with the buyer. As of September 30, 2010, the Company completed the transfer of remaining manufacturing processes from its Carolina, Puerto Rico manufacturing facility to its plant in Steinbach, Manitoba. Following the end of production, the Company incurred internal and external costs of $1.3 million directly associated with the final shutdown of the Carolina facility, which costs have been recognized as restructuring costs. The Company also recorded an impairment charge of $0.4 million to write off the remaining carrying value of the Carolina facility after unsuccessful efforts to locate a buyer for the facility. The Company incurred employee termination costs of $9.6 million in total for severance and related benefits payable to the approximately 240 employees terminated as a result of the closure of the Dorado and Carolina facilities. As these employees were required to provide service during the shutdown period in order to be eligible for termination benefits, the Company was recognizing the cost of those termination benefits ratably over the estimated future service period. In 2009 and 2008, the Company recorded impairment charges of $7.6 million and $42.6 million, respectively, to write down the carrying value of the property, plant and equipment located in Puerto Rico to its estimated fair value. F-28 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 6. RESTRUCTURING AND INTEGRATION (Continued) Pharmaceutical Sciences Operations On July 23, 2010, the Company completed the sale of CRD to Lambda Therapeutic Research Inc. (‘‘Lambda’’) for net cash proceeds of $6.4 million. The Company no longer considered CRD a strategic fit as a result of its pre-Merger transition from reformulation programs to the in-licensing, acquisition and development of specialty CNS products. CRD has not been treated as a discontinued operation for accounting purposes, on the basis that its operations were immaterial and incidental to the Company’s core business. The net assets of CRD at the date of disposal comprised net current assets and liabilities of $1.6 million and property, plant and equipment of $4.8 million. The Company recognized employee termination costs of $1.9 million for the approximately 70 CRD employees not offered employment by Lambda. The consolidated statements of income (loss) for the years ended December 31, 2010, 2009 and 2008 included the following revenue and expenses of CRD, which, as described above, have not been segregated from continuing operations: Service and other revenues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 5,642 $12,027 $21,191 Cost of services . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Selling, general and administrative expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Total operating expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7,211 2,328 9,539 13,849 3,718 23,033 4,150 17,567 27,183 Operating loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Foreign exchange gain (loss) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (3,897) (102) (5,540) 93 (5,992) 931 Net loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $(3,999) $ (5,447) $ (5,061) 2010 2009 2008 In 2009, the Company incurred employee termination costs of $1.4 million for severance and related benefits payable to the approximately 50 employees terminated as a result of the closure of its Mississauga, Ontario research and development facility and the consolidation of its Chantilly, Virginia research and development operations. In addition, the Company recorded an impairment charge of $0.5 million related to the write-down of the carrying value of the equipment and leasehold improvements located at the Mississauga facility to their estimated fair value. The Company also recognized $1.6 million of accelerated depreciation arising from the reduced useful life of the leasehold improvements located at the Chantilly facility, and incurred lease termination costs of $1.4 million as a result of vacating one of its premises in Chantilly in 2009. In addition, in 2009, the Company completed the sale of its Dublin, Ireland research and development facility for net cash proceeds of $5.2 million, which resulted in a write-down of $9.9 million to the carrying value of this facility. The Company had closed this facility in August 2008 and recognized employee termination costs of $2.7 million for the approximately 50 employees affected by this closure. In 2008, the Company recorded an impairment charge of $7.5 million to write off the carrying value of certain proprietary drug-delivery technologies that were not expected to be utilized in the development of specialty CNS products. Corporate Headquarters On November 4, 2009, the Company completed the sale and leaseback of its corporate headquarters in Mississauga, Ontario for net proceeds of $17.8 million. The Company recognized a loss on disposal of $11.0 million. The Company has continued to occupy this facility under a 20-year operating lease at market rental rates. Minimum future rental payments under this lease are approximately $43.1 million. The Company’s intention is to vacate this facility in the first half of 2011 and relocate to a smaller leased facility. F-29 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 7. FAIR VALUE MEASUREMENTS Assets Measured at Fair Value on a Recurring Basis The following fair value hierarchy table presents the components and classification of the Company’s financial assets measured at fair value as of December 31, 2010 and 2009: 2010 2009 Quoted Prices in Active Markets for Significant Other Significant Quoted Prices in Active Markets for Significant Other Significant Identical Observable Unobservable Identical Observable Unobservable Carrying Value Assets (Level 1) Inputs (Level 2) Inputs (Level 3) Carrying Value Assets (Level 1) Inputs (Level 2) Inputs (Level 3) Money market funds Available-for-sale debt . . . . . $91,448 $91,448 $ — $— $ 7,994 $7,994 $ — $ — securities: Corporate bonds . . . . . . . Government-sponsored enterprise securities . . . Auction rate securities . . . 6,340 1,826 — — — — 6,340 1,826 — Total financial assets . . . . . . $99,614 $91,448 $8,166 Cash and cash equivalents . . Marketable securities . . . . . $91,448 8,166 $91,448 — Total financial assets . . . . . . $99,614 $91,448 $ — 8,166 $8,166 — — — $— $— — $— 10,880 4,193 6,009 — — — 10,880 — 4,193 — $29,076 $7,994 $15,073 $ 7,994 21,082 $7,994 — $ — 15,073 $29,076 $7,994 $15,073 — 6,009 $6,009 $ — 6,009 $6,009 Fair value measurements are estimated based on valuation techniques and inputs categorized as follows: • Level 1 — Quoted prices (unadjusted) for identical securities in active markets. • Level 2 — Quoted prices (unadjusted) for identical securities in markets that are not active. • Level 3 — Discounted cash flow method (income approach) using significant inputs not observable in the market. As of December 31, 2010 and 2009, the Company did not have any financial liabilities that were subject to fair value measurements. Assets Measured at Fair Value on a Recurring Basis Using Significant Unobservable Inputs (Level 3) As of December 31, 2009, the Company’s marketable securities portfolio included $26.8 million of principal invested in nine individual auction rate securities, which had an estimated fair value of $6.0 million at that date. In May 2009, the Company had received $22.0 million in a settlement with an investment bank in respect of these securities, and retained ownership of the securities under the terms of the settlement. In August 2010, the Company disposed of these securities for cash proceeds of $1.4 million. F-30 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 7. FAIR VALUE MEASUREMENTS (Continued) The following table presents a reconciliation of the auction rate securities measured at fair value on a recurring basis using significant unobservable inputs (Level 3) for the years ended December 31, 2010 and 2009: Balance, beginning of year . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Total unrealized gains (losses): Included in net income (loss)(1): 2010 2009 $ 6,009 $10,333 Arising during year . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Reclassification from other comprehensive income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (5,163) (389) (4,479) (731) Included in other comprehensive income: Arising during year . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Reclassification to net income (loss) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Proceeds on disposal 554 389 (1,400) 155 731 — Balance, end of year . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ — $ 6,009 Total amount of unrealized losses for the year included in net income (loss) relating to securities still held at end of year . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ — $ (5,210) (1) Included in gain (loss) on investments, net (as described in note 20). Assets and Liabilities Measured at Fair Value on a Non-Recurring Basis As of December 31, 2010, the Company’s assets measured at fair value on a non-recurring basis subsequent to initial recognition consisted of a property in Warsaw, Poland held for sale by Valeant. The fair value less costs to sell of this property was determined at the Merger Date to be $4.0 million based on observed prices for comparable market transactions, which represent Level 2 inputs. No change in fair value was recognized in the period ended December 31, 2010. 8. FAIR VALUE OF FINANCIAL INSTRUMENTS The following table summarizes the estimated fair values of the Company’s financial instruments as of December 31, 2010 and 2009: 2010 2009 Carrying Value Fair Value Carrying Value Fair Value Cash equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Marketable securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Long-term debt (as described in note 14) . . . . . . . . . . . . . . . . . . . . . . . $ 91,448 8,166 (3,595,277) $ 91,448 8,166 (4,174,561) $ 7,994 21,082 (326,085) $ 7,994 21,082 (434,518) The following table summarizes the Company’s marketable securities by major security type as of December 31, 2010 and 2009: 2010 2009 Cost Basis Fair Value Gross Unrealized Gains Losses Cost Basis Fair Value Gross Unrealized Gains Losses Corporate bonds Government-sponsored enterprise . . . . . . . . . . . . . . . . $6,234 6,340 $106 securities . . . . . . . . . . . . . . . . . . . . Auction rate securities . . . . . . . . . . . . . 1,825 — 1,826 — $8,059 $8,166 1 — $107 $— — — $— $10,626 $10,880 $254 $ — 4,100 26,775 4,193 6,009 93 — — (20,766) $41,501 $21,082 $347 $(20,766) F-31 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 8. FAIR VALUE OF FINANCIAL INSTRUMENTS (Continued) The contractual maturities of marketable securities held as of December 31, 2010 were as follows: Within one year . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . One to two years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $6,083 2,083 $6,083 2,083 $8,166 $8,166 Gross gains and losses realized on the sale of marketable securities were not material in the years ended December 31, 2010, 2009 or 2008. Carrying Value Fair Value 9. ACCOUNTS RECEIVABLE The components of accounts receivable as of December 31, 2010 and 2009 were as follows: Trade . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Less allowance for doubtful accounts $240,712 (6,692) $101,853 (2,437) 2010 2009 Royalties . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234,020 16,424 24,375 99,416 6,313 6,436 $274,819 $112,165 The increase in accounts receivable primarily reflects the addition of Valeant’s revenues from products and services, commencing from the Merger Date. 10. INVENTORIES The components of inventories as of December 31, 2010 and 2009 were as follows: Raw materials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Work in process . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Finished goods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 55,486 43,587 158,574 $15,322 29,155 46,856 2010 2009 Less allowance for obsolescence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257,647 (28,065) 91,333 (8,560) $229,582 $82,773 The increase in inventories primarily reflect the acquisition of Valeant’s inventories, which were recorded at fair value (as described in note 3). In the post-Merger period ended December 31, 2010, cost of goods sold includes $53.3 million of the acquisition accounting adjustment on Valeant’s inventory that was sold subsequent to the Merger Date. F-32 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 11. PROPERTY, PLANT AND EQUIPMENT The major components of property, plant and equipment as of December 31, 2010 and 2009 were as follows: Land . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Buildings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Machinery and equipment Other equipment and leasehold improvements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Construction in progress . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 25,528 159,712 145,292 65,597 8,334 $ 3,398 80,560 74,560 56,248 7,180 2010 2009 Less accumulated depreciation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404,463 (122,711) 221,946 (118,098) $ 281,752 $ 103,848 The increase in the gross carrying value primarily reflects the acquisition of Valeant’s property, plant and equipment, which were recorded at fair value (as described in note 3). Depreciation expense amounted to $23.9 million, $18.8 million and $25.8 million in the years ended December 31, 2010, 2009 and 2008, respectively. 12. INTANGIBLE ASSETS AND GOODWILL Intangible Assets The major components of intangible assets as of December 31, 2010 and 2009 were as follows: Finite-lived intangible assets: Product brands . . . . . . . . . Corporate brands . . . . . . . Product rights . . . . . . . . . . Out-licensed technology and other . . . . . . . . . . . . . . Total finite-lived intangible assets . . . . . . . . . . . . Indefinite-lived intangible assets: Acquired IPR&D . . . . . . . Weighted- Average Useful Lives (Years) 2010 2009 Gross Carrying Amount Accumulated Amortization Net Carrying Amount Gross Carrying Amount Accumulated Amortization Net Carrying Amount 15 20 11 7 14 $4,227,465 169,675 1,074,611 $(404,951) (2,191) (279,275) $3,822,514 167,484 795,336 $1,084,226 — 693,126 $(267,249) — (202,881) $ 816,977 — 490,245 205,332 (17,842) 187,490 — — — 5,677,083 (704,259) 4,972,824 1,777,352 (470,130) 1,307,222 NA 1,399,956 — 1,399,956 28,000 — 28,000 $7,077,039 $(704,259) $6,372,780 $1,805,352 $(470,130) $1,335,222 The increase in intangible assets primarily reflects the acquisition of Valeant’s identifiable intangible assets, which were recorded at fair value (as described in note 3). For the years ended December 31, 2010, 2009 and 2008, amortization expense related to intangible assets was recorded as follows: Royalty and other revenue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cost of goods sold . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Amortization expense . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 1,072 8,103 219,758 $ 1,072 8,103 104,730 $ 1,072 8,103 51,369 $228,933 $113,905 $60,544 2010 2009 2008 F-33 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 12. INTANGIBLE ASSETS AND GOODWILL (Continued) In the post-Merger period ended December 31, 2010, amortization expense included $58.7 million related to the fair-value increment for Valeant’s identifiable intangible assets. Estimated aggregate amortization expense for each of the five succeeding years ending December 31 is as follows: Amortization expense . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $458,407 $450,384 $447,991 $439,914 $420,836 2011 2012 2013 2014 2015 Goodwill As of the Merger Date, the Company reassigned its existing goodwill to affected reporting units using a relative fair value approach. The change in the carrying amount of goodwill from the Merger Date to December 31, 2010 was as follows: Balance, September 28, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . Acquisition of Valeant Foreign exchange and other . . . . . . . . . . . . U.S. Neurology and Other $ 68,029 1,311,487 — U.S. Dermatology Canada and Australia Branded Generics — Europe Branded Generics — Latin America $ 18,495 480,043 (30) $ 9,655 369,493 15,639 $ 4,115 350,876 (2,255) $ — 366,957 8,872 Total $ 100,294 2,878,856 22,226 Balance, December 31, 2010 . . . . . . . . . . . $1,379,516 $498,508 $394,787 $352,736 $375,829 $3,001,376 As described in note 3, the allocation of goodwill is provisional and subject to the completion of the allocation of the consideration transferred to the assets acquired and liabilities assumed. 13. ACCRUED LIABILITIES The major components of accrued liabilities as of December 31, 2010 and 2009 were as follows: 2010 2009 Product returns . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Product rebates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Employee costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Interest . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Restructuring costs (as described in note 6) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Legal settlements (as described in note 24) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Professional fees Royalties . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Unpaid cash consideration related to the Merger (as described in note 3) . . . . . . . . . . . . . . . . . . . . . . DSUs (as described in note 17) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $110,642 79,704 49,756 41,800 30,139 16,000 15,488 14,594 13,281 11,495 59,215 $ 24,584 20,934 17,536 11,627 10,776 7,950 5,601 9,934 — 4,796 8,356 $442,114 $122,094 The increase in accrued liabilities primarily reflects the assumption of Valeant’s product sales provisions, employee costs and interest obligations. F-34 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 14. LONG-TERM DEBT Long-term debt as of December 31, 2010 and 2009 comprised the following: Term Loan A Facility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2017 Notes, net of unamortized debt discount of $2,411 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2020 Notes, net of unamortized debt discount of $4,265 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2018 Notes, net of unamortized debt discount of $7,502 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5.375% Convertible Notes, net of unamortized debt discount (2010 — $26,970; 2009 — $51,715) . . . . . . . 4.0% Convertible Notes, net of unamortized debt discount of $4,118 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cambridge obligation, net of unamortized debt discount (2010 — $600; 2009 — $2,200) $ 975,000 497,589 695,735 992,498 196,763 220,792 16,900 $ — — — — 298,285 — 27,800 2010 2009 Less current portion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3,595,277 (116,900) 326,085 (12,110) $3,478,377 $313,975 Aggregate maturities of long-term debt for each of the five succeeding years ending December 31 and thereafter are as follows: 2011 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2012 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2013 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2014 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2015 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Thereafter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 117,500 125,000 424,910 473,733 300,000 2,200,000 Total gross maturities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Unamortized discounts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3,641,143 (45,866) Total long-term debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $3,595,277 Credit Facilities On September 27, 2010, Valeant and certain of its subsidiaries entered into a Credit and Guaranty Agreement (the ‘‘Credit Agreement’’) with a syndicate of lending institutions, consisting of (1) a four-and-one-half-year non-amortizing $125.0 million Revolving Credit Facility, (2) a five-year amortizing $1.0 billion Term Loan A Facility, and (3) a six-year amortizing $1.625 billion Term Loan B Facility, consisting of a $1.5 billion ‘‘initial draw’’ and a $125.0 million ‘‘delayed draw’’ (together the ‘‘Credit Facilities’’). On September 28, 2010, the Company and certain of its subsidiaries (other than Valeant and its subsidiaries) entered into Counterpart Agreements or Deeds of Guarantee, as appropriate, to the Credit Agreement, pursuant to which they guaranteed the Credit Facilities, each in substantially the same form. As described in note 3, the loans under the Term Loan A Facility and the ‘‘initial draw’’ under the Term Loan B Facility were used for the purposes of refinancing the Valeant debt, funding the pre-Merger special dividend, and for the payment of fees and expenses of Valeant related to the Merger and financings. The Revolving Credit Facility can be used for working capital and general corporate purposes of the Company and its subsidiaries. On November 29, 2010, the ‘‘delayed draw’’ under the Term Loan B Facility was terminated. As of December 31, 2010, the ‘‘initial draw’’ under the Term Loan B Facility had been paid in full. The Credit Facilities provide that Valeant has the right at any time to seek commitments from the lenders under the Credit Facilities to provide additional term loan facilities or additional revolving credit commitments in an aggregate principal amount of up to $250.0 million. The lenders under the Credit Facilities are not under any obligation to provide any such additional term loan facilities or revolving credit commitments. Borrowings under the Credit Facilities bear interest at a rate per annum equal to, at Valeant’s option, either (a) a base rate determined by reference to the higher of (1) the prime rate, (2) the federal funds effective rate plus 1⁄2 of 1%, and (3) a LIBO rate determined by reference to the costs of funds for U.S. dollar deposits for a one-month interest period adjusted for certain additional costs plus 1%, or (b) a LIBO rate determined by reference to the costs of funds for U.S. dollar deposits for the interest period relevant to such borrowing adjusted for certain additional costs, in each case plus an applicable margin. For the purpose of determining the interest rate payable on loans under the Term Loan B Facility under clauses (a) and (b) of the immediately preceding sentence, the base rate and LIBO rate will F-35 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 14. LONG-TERM DEBT (Continued) in no event be less than 2.50% and 1.50%, respectively. The applicable margin for borrowings under the Credit Facilities is 3.00% with respect to base rate borrowings and 4.00% with respect to LIBO rate borrowings. The Revolving Credit Facility includes a sublimit for the issuance of standby and commercial letters of credit and a sublimit for swing line loans. Swing line loans will bear interest at a rate per annum equal to the base rate described in clause (a) of the preceding paragraph plus the applicable margin. Subject to certain exceptions and customary baskets set forth in the Credit Agreement, Valeant will be required to make mandatory prepayments of the loans under the Term Loan A Facility and the Term Loan B Facility, on a pro rata basis, under certain circumstances, including from (1) 100% of net cash proceeds from asset sales outside the ordinary course of business (subject to the right to reinvest these proceeds in real estate, equipment and other tangible assets useful in the business of the Company and its subsidiaries (‘‘reinvestment rights’’), (2) 100% of the net cash proceeds of insurance and condemnation proceeds for property or asset losses (subject to reinvestment rights and net proceeds threshold), (3) 50% (with a step down to 25% based on achievement of a specified leverage ratio) of the net cash proceeds received from certain issuances of equity interests, (4) 100% of the net cash proceeds from the incurrence of debt not otherwise permitted by the terms of the Credit Agreement and (5) 50% of annual excess cash flow (with a step down to 25% based on achievement of a specified leverage ratio), with any excess amounts after the prepayment of the loans under the Term Loan A Facility and the Term Loan B Facility to be applied against the outstanding amounts under the Revolving Credit Facility. Valeant is permitted to voluntarily reduce the unutilized portion of the commitment amount and repay outstanding loans under the Credit Facilities at any time without premium or penalty, other than customary ‘‘breakage’’ costs with respect to LIBO rate loans. The Term Loan A Facility will mature on the five-year anniversary of the closing date for the Credit Facilities and will amortize in equal quarterly installments of 2.5% of the original principal amount (i.e., 10% annually) for each of the first and second years after such closing date and in equal quarterly installments of 5% of the original principal amount (i.e., 20% annually) for each of the third and fourth years after such closing date, with the remaining 40% balance amortizing in equal 10% quarterly installments in the last year. The Revolving Credit Facility will mature on the four-and-one-half-year anniversary of the closing date for the Credit Facilities and will not amortize. Valeant’s obligations under the Credit Facilities, as well as certain hedging arrangements and cash management arrangements entered into with lenders under the Credit Facilities (or affiliates thereof), are guaranteed by the Company’s existing and future direct and indirect subsidiaries (other than Valeant), in each case excluding immaterial subsidiaries designated by the Company or Valeant from time to time that, individually or in the aggregate, constitute less than (1) 7.5% of the consolidated total assets of the Company or its subsidiaries as of the time of designation, and (2) 7.5% of the total revenues of the Company and its consolidated subsidiaries for the four-fiscal-quarter period most recently ended prior to such date of designation and, in each case subject to certain exclusions set forth in the credit documentation governing the Credit Facilities. Valeant’s obligations and the obligations of the guarantors under the Credit Facilities and certain hedging arrangements and cash management arrangements entered into with lenders under the Credit Facilities (or affiliates thereof) are secured by first-priority security interests in substantially all tangible and intangible assets of Valeant and the guarantors, including 100% of the capital stock of Valeant and each domestic subsidiary of Valeant, 65% of the capital stock of each foreign subsidiary of Valeant that is directly owned by Valeant or a domestic subsidiary of Valeant, and 100% of the capital stock of each subsidiary of the Company (other than Valeant and any of its subsidiaries) that is owned by a guarantor, in each case, subject to exclusions set forth in the credit documentation governing the Credit Facilities. The Credit Facilities contain a number of covenants that, among other things and subject to certain exceptions, restrict the right of the Company and certain of its subsidiaries to: incur additional indebtedness; create liens; enter into agreements and other arrangements that include negative pledge clauses; pay dividends on capital stock or redeem, repurchase or retire capital stock or subordinated indebtedness; create restrictions on the payment of dividends or other distributions by subsidiaries; make investments, loans, advances and acquisitions; merge, amalgamate or sell assets, including equity interests of the subsidiaries; enter into sale and leaseback transactions; engage in transactions with affiliates; enter into new lines of business; and enter into amendments of or waivers under subordinated indebtedness, organizational documents and certain other material agreements. The Credit Agreement requires that the Company maintain a minimum interest coverage ratio of 2.25 to 1.00 in the fiscal quarter ending December 31, 2010 and increasing to 3.00 to 1.00 by the fiscal quarter ended March 31, 2013, and a maximum leverage ratio of 3.50 to 1.00 in the fiscal quarter ending December 31, 2010 and decreasing to 2.75 to 1.00 by the fiscal quarter ended March 31, 2014 (provided, however, that prior to incurrence of additional debt the leverage ratio must be at least 0.25 times lower than the leverage ratio for the applicable period on a pro forma basis, as defined in the Credit Agreement, after giving effect to the incurrence of such indebtedness). In addition, the Credit Agreement limits the aggregate amount of capital expenditures permitted to be made during any F-36 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 14. LONG-TERM DEBT (Continued) fiscal year to $55.0 million, subject to a limited one-year carryforward of up to a maximum amount of $27.5 million for the unused capital expenditures capacity in the immediately preceding fiscal year. The Credit Agreement also contains certain customary representations, warranties, affirmative covenants and events of default. If an event of default, as specified in the Credit Agreement, shall occur and be continuing, Valeant may be required to repay all amounts outstanding under the Credit Facilities. As of December 31, 2010, the Company was in compliance with all covenants associated with the Credit Facilities. As of December 31, 2010, the estimated fair value of the Credit Facilities approximated its carrying value based on current borrowing rates available to the Company. 2017 Notes and 2020 Notes Concurrent with the closing of the Merger, Valeant issued $500.0 million aggregate principal amount of 2017 Notes and $700.0 million aggregate principal amount of 2020 Notes in a private placement. The 2017 Notes mature on October 1, 2017 and the 2020 Notes mature on October 1, 2020. Interest on the 2017 Notes and 2020 Notes accrues at the rate of 6.75% and 7.00%, respectively, and will be payable semi-annually in arrears on each April 1 and October 1, commencing on April 1, 2011. The 2017 Notes were issued at a discount of 99.5% for an effective annual yield of 6.84% and the 2020 Notes were issued at a discount of 99.375% for an effective annual yield of 7.09%. The 2017 Notes and 2020 Notes are the senior unsecured obligations of Valeant and are jointly and severally guaranteed on a senior unsecured basis by the Company and each of its subsidiaries (other than Valeant) that is a guarantor under the Credit Facilities (as described above). Certain of the future subsidiaries of the Company may be required to guarantee the 2017 Notes and 2020 Notes. A portion of the proceeds of the 2017 Notes and 2020 Notes offering was used to repay $1.0 billion of the Term Loan B Facility (as described above) and the remaining portion will be used for general corporate purposes. Valeant may redeem all or a portion of the 2017 Notes at any time prior to October 1, 2014, and Valeant may redeem all or a portion of the 2020 Notes at any time prior to October 1, 2015, in each case at a price equal to 100% of the principal amount thereof, plus accrued and unpaid interest, if any, to the date of redemption, plus a ‘‘make-whole’’ premium, as set forth in the 2017 Notes and 2020 Notes Indenture. On or after October 1, 2014, Valeant may redeem all or a portion of the 2017 Notes, and on or after October 1, 2015, Valeant may redeem all or a portion of the 2020 Notes, in each case at the redemption prices applicable to the 2017 Notes or the 2020 Notes, as set forth in the 2017 Notes and 2020 Notes Indenture, plus accrued and unpaid interest to the date of redemption. In addition, prior to October 1, 2013, Valeant may redeem up to 35% of the aggregate principal amount of either the 2017 Notes or the 2020 Notes at prices of 106.750% and 107.000%, respectively, of the principal amount thereof, plus accrued and unpaid interest to the date of redemption, in each case with the net proceeds of certain equity offerings. If Valeant or the Company experiences a change of control, Valeant may be required to repurchase the 2017 Notes and 2020 Notes, in whole or in part, at a purchase price equal to 101% of the principal amount thereof, plus accrued and unpaid interest to, but excluding, the purchase date. The 2017 Notes and 2020 Notes Indenture contains covenants that limit the ability of the Company and certain of its subsidiaries to, among other things: incur or guarantee additional debt; make certain investments and other restricted payments; create liens; enter into transactions with affiliates; engage in mergers, consolidations or amalgamations; repurchase capital stock, repurchase subordinated debt and make certain investments; and transfer and sell assets. If an event of default, as specified in the 2017 Notes and 2020 Notes Indenture, shall occur and be continuing, either the trustee or the holders of a specified percentage of the 2017 Notes and 2020 Notes may accelerate the maturity of all the 2017 Notes and 2020 Notes. As of December 31, 2010, the fair values of the 2017 Notes and 2020 Notes were approximately $500.3 million and $694.3 million, respectively, in the secondary market. 2018 Notes On November 23, 2010, Valeant issued $1.0 billion aggregate principal amount of 6.875% Senior Notes due 2018 (the ‘‘2018 Notes’’ and, together with the 2017 Notes and 2020 Notes, the ‘‘Notes’’) in a private placement. The 2018 Notes mature on December 1, 2018. Interest on the 2018 Notes accrues at a rate of 6.875% and will be payable semi-annually in arrears on each June 1 and December 1, commencing on June 1, 2011. The 2018 Notes were issued at a discount of 99.24% for an effective annual yield of 7.0%. The 2018 Notes are the senior unsecured obligations of Valeant and are jointly and severally guaranteed on a senior unsecured basis by the Company and each of its subsidiaries (other than Valeant) that is a guarantor under the Credit Facilities (as described above). Certain of the future subsidiaries of Valeant and the Company may be required to guarantee the 2018 Notes. F-37 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 14. LONG-TERM DEBT (Continued) A portion of the proceeds of the 2018 Notes offering was used to repay the remaining $500.0 million owed under the Term Loan B Facility (as described above) and the balance of the proceeds are expected to be used for general corporate purposes, including acquisitions, debt repayment and securities repurchases. Valeant may redeem all or a portion of the 2018 Notes at any time prior to December 1, 2014, at a price equal to 100% of the principal amount thereof, plus accrued and unpaid interest, if any, to the date of redemption, plus a ‘‘make-whole’’ premium, as set forth in the 2018 Notes Indenture. On or after December 1, 2014, Valeant may redeem all or a portion of the 2018 Notes at the redemption prices applicable to the 2018 Notes, as set forth in the 2018 Notes Indenture, plus accrued and unpaid interest to the date of redemption. In addition, prior to December 1, 2013, Valeant may redeem up to 35% of the aggregate principal amount of the 2018 Notes at 106.875% of the principal amount thereof, plus accrued and unpaid interest to the date of redemption, in each case with the net proceeds of certain equity offerings. If Valeant or the Company experiences a change of control, Valeant may be required to repurchase the 2018 Notes, in whole or in part, at a purchase price equal to 101% of the principal amount thereof, plus accrued and unpaid interest to, but excluding, the purchase date. The 2018 Notes Indenture contains covenants consistent with those contained in the 2017 Notes and 2020 Notes Indenture (as described above). As of December 31, 2010, the fair value of the 2018 Notes was approximately $992.5 million in the secondary market. 5.375% Convertible Notes On June 10, 2009, the Company issued $350.0 million principal amount of 5.375% senior convertible notes due August 1, 2014 (the ‘‘5.375% Convertible Notes’’ and, together with the 4.0% Convertible Notes, the ‘‘Convertible Notes’’). The 5.375% Convertible Notes mature on August 1, 2014. The 5.375% Convertible Notes were issued at par and pay interest semi-annually on February 1 and August 1 of each year. The 5.375% Convertible Notes may be converted based on a current conversion rate of 69.6943 common shares of the Company per $1,000 principal amount of notes, which represents a conversion price of approximately $14.35 per share. The conversion rate will be adjusted if the Company makes specified types of distributions or enters into certain other transactions in respect of its common shares. In addition, following certain corporate transactions that occur prior to maturity, the conversion rate will be increased for holders who elect to convert their holdings in connection with such corporate transactions. The 5.375% Convertible Notes are convertible at any time prior to the maturity date under the following circumstances: • during any calendar quarter if the closing price of the Company’s common shares exceeds 130% of the conversion price then in effect during a defined period at the end of the previous quarter; • during a defined period if the trading price of the 5.375% Convertible Notes falls below specified thresholds for a defined trading period; • if the 5.375% Convertible Notes have been called for redemption; • upon the occurrence of specified corporate transactions; or • 25 trading days prior to the maturity date. Upon conversion, the 5.375% Convertible Notes may be settled in cash, common shares, or a combination of cash and common shares, at the Company’s option. The Company’s current intent is to settle the 5.375% Convertible Notes using a net share settlement approach, such that the principal amount of any 5.375% Convertible Notes tendered for conversion would be settled in cash, and any excess conversion value settled in common shares. The Company may redeem for cash all or a portion of the 5.375% Convertible Notes at any time on or after August 2, 2012, at a price equal to 100% of the principal amount of the 5.375% Convertible Notes to be redeemed, plus any accrued and unpaid interest, if during a defined period the closing price of the Company’s common shares exceeds 130% of the conversion price then in effect. The Company may not otherwise redeem any of the 5.375% Convertible Notes at its option prior to maturity, except upon the occurrence of certain changes to the laws governing Canadian withholding taxes. Holders may require the Company to repurchase for cash all or a portion of their holdings at 100% of the principal amount of the 5.375% Convertible Notes to be purchased, plus any accrued and unpaid interest, upon the occurrence of a specified fundamental change (such as a change of control). At the date of issuance, the principal amount of the 5.375% Convertible Notes was allocated into a liability component and an equity component. The liability component was fair valued at $293.3 million, based on a 9.5% market rate of interest for similar debt with no conversion rights. The value allocated to the liability component is being accreted to the face value of the 5.375% Convertible Notes F-38 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 14. LONG-TERM DEBT (Continued) over the five-year period prior to maturity, using the effective interest method. The accretion of the liability component is being recognized as additional non-cash interest expense. The difference between the principal amount of the 5.375% Convertible Notes and the value allocated to the liability component of $56.7 million was recorded in additional paid-in capital in shareholders’ equity, as the carrying amount of the equity component. In connection with the issuance of the 5.375% Convertible Notes, the Company incurred financing costs of $16.5 million, which were allocated to the liability and equity components in proportion to the preceding allocation of the principal amount of the 5.375% Convertible Notes. In November and December 2010, the Company repurchased $126.3 million aggregate principal amount of the 5.375% Convertible Notes for an aggregate purchase price of $259.2 million. The carrying amount of the 5.375% Convertible Notes purchased was $106.9 million (net of $3.9 million of related unamortized deferred financing costs) and the estimated fair value of the 5.375% Convertible Notes exclusive of the conversion feature was $127.5 million. The difference of $20.7 million between the net carrying amount and the estimated fair value was recognized as a loss on extinguishment of debt (as described in note 19). The difference of $131.7 million between the estimated fair value of $127.5 million and the purchase price of $259.2 million was charged to shareholders’ equity, as a reduction of additional paid-in capital and a charge to accumulated deficit of $20.4 million and $111.3 million, respectively. The portion of the purchase price attributable to accreted interest on the debt discount amounted to $4.9 million, and is presented in the consolidated statements of cash flows as payment of accreted interest in cash flows from operating activities. Interest expense was recognized based on the effective rate of interest of 9.5% on the liability component of the 5.375% Convertible Notes as follows: Cash interest per contractual coupon rate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Non-cash amortization of debt discount $18,335 9,265 $10,504 4,954 $27,600 $15,458 2010 2009 In addition, interest expense included the non-cash amortization of deferred financing costs associated with the 5.375% Convertible Notes of $2.1 million and $1.0 million in 2010 and 2009, respectively. As of December 31, 2010 and 2009, the estimated fair values of the 5.375% Convertible Notes were approximately $467.4 million and $406.7 million, respectively, based on quoted market prices. The if-converted value of the 5.375% Convertible Notes exceeded the principal amount by $217.4 million at December 31, 2010. 4.0% Convertible Notes As described in note 3, in connection with the Merger, the Company assumed $225.0 million aggregate outstanding principal amount of Valeant’s 4.0% Convertible Notes. Interest on the 4.0% Convertible Notes is payable semi-annually on May 15 and November 15 of each year. The 4.0% Convertible Notes mature on November 15, 2013. Valeant has the right to redeem the 4.0% Convertible Notes, in whole or in part, at their principal amount on or after May 20, 2011. The 4.0% Convertible Notes are convertible into common shares of the Company at a current conversion rate of 79.0667 shares per $1,000 principal amount of notes (which represents a conversion price of approximately $12.65 per share), reflecting an adjustment to account for the pre-Merger special dividend, the exchange ratio for the Merger and the post-Merger special dividend. Upon conversion, the Company may satisfy the conversion obligations, at its option, in common shares, in cash, or in a combination thereof. The Company’s current intent is to settle the 4.0% Convertible Notes using a net share settlement approach, such that the principal amount of any 4.0% Convertible Notes tendered for conversion would be settled in cash, and any excess conversion value settled in common shares. The fair value of $220.5 million allocated to the liability component of the 4.0% Convertible Notes, as of the Merger Date, will be accreted to the face value of the 4.0% Convertible Notes through the debt maturity date of November 15, 2013, using the effective interest rate method. The accretion of the liability component will be recognized as additional non-cash interest expense. The effective interest rate on the liability component of the 4.0% Convertible Notes is 4.62%. For the period from the Merger Date to December 31, F-39 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 14. LONG-TERM DEBT (Continued) 2010, interest expense was recognized based on the effective rate of interest on the liability component of the 4.0% Convertible Notes as follows: Cash interest per contractual coupon rate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Non-cash amortization of debt discount . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2010 $2,324 304 $2,628 As of December 31, 2010, the estimated fair value of the 4.0% Convertible Notes was determined to be approximately $528.1 million, based on quoted market prices. The if-converted value of the 4.0% Convertible Notes exceeded the principal amount by $278.2 million at December 31, 2010. Cambridge Obligation In connection with the acquisition of the worldwide development and commercialization rights to tetrabenazine (as described in note 4), the Company made a payment of $12.5 million to Cambridge on June 21, 2010 and the Company will make a final payment of $17.5 million to Cambridge on June 20, 2011. These payments were discounted based on imputed interest rates of 6.9% and 7.7%, respectively. In 2010 and 2009, interest expense included the non-cash amortization of the debt discount on the Cambridge obligation of $1.6 million and $1.0 million, respectively. As of December 31, 2010, the fair value of the Cambridge obligation approximated its carrying value based on current borrowing rates available to the Company. Former Credit Facility On June 9, 2009, the Company established a $410.0 million senior secured revolving credit facility maturing on June 9, 2012. In connection with the establishment of the Credit Facilities described above, this former facility was terminated effective September 28, 2010, and the Company wrote off $5.8 million of related deferred financing costs. 15. PENSION AND POSTRETIREMENT EMPLOYEE BENEFIT PLANS The Company operates defined contribution retirement plans in several countries, including Canada and the U.S. Under these plans, employees are allowed to contribute a portion of their salaries to the plans, and the Company matches a portion of the employee contributions. The Company contributed $2.9 million, $2.3 million and $2.6 million to these plans in the years ended December 31, 2010, 2009 and 2008, respectively. Outside of the U.S., certain groups of Valeant employees are covered by defined benefit retirement and post-employment plans. The Company assumed all of Valeant’s defined benefit obligations and related plan assets in connection with the Merger. The Company contributed $1.4 million to these plans from the Merger Date to December 31, 2010. As of December 31, 2010, the projected benefit obligation of these plans totaled $10.4 million, which exceeded the fair value of plan assets of $5.8 million by $4.6 million. The Company has recognized the under-funded financial position of these plans in accrued liabilities ($0.3 million) and other long-term liabilities ($4.3 million) as of December 31, 2010. The net periodic benefit cost of these plans was not material to the Company’s results of operations. 16. SECURITIES REPURCHASE PROGRAM On November 4, 2010, the Company announced that the board of directors approved a securities repurchase program (the ‘‘securities repurchase program’’), pursuant to which the Company may make purchases of its common shares, Convertible Notes and/or Notes up to an aggregate maximum value of $1.5 billion, subject to any restrictions in the Company’s financing agreements and applicable law. The board of directors also approved a sub-limit of up to 16,000,000 common shares, representing approximately 10% of the Company’s public float (as estimated at the commencement of the securities repurchase program), to be purchased for cancellation under a normal course issuer bid through the facilities of the NYSE and Toronto Stock Exchange (‘‘TSX’’). The Company may initially make purchases under the securities repurchase program of up to 15,000,000 common shares through the facilities of the NYSE, in accordance with applicable rules and guidelines. This represented approximately 5% of the Company’s issued and outstanding common shares as of F-40 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 16. SECURITIES REPURCHASE PROGRAM (Continued) November 4, 2010. Following additional filings and related approvals, the Company may also purchase common shares over the TSX. The program does not require the Company to repurchase a minimum number of securities, and the program may be modified, suspended or terminated at any time without prior notice. The securities repurchase program will terminate on November 7, 2011 or at such earlier time as the Company completes its purchases. Under the terms of the Credit Facilities, the Company purchases under the securities repurchase program are subject to certain monetary thresholds, above which the Company requires the consent of the lenders. In connection with the securities repurchase program, the Company repurchased $126.3 million aggregate principal amount of the 5.375% Convertible Notes at an aggregate purchase price of $259.2 million (as described in note 14). In addition, the Company repurchased 2,305,000 common shares at an average price of $26.08 per share, for total cash consideration of $60.1 million. The excess of the cost of the common shares repurchased over their assigned value, totaling $19.7 million, was charged to accumulated deficit. In January 2011, the Company repurchased an additional $11.4 million principal amount of the 5.375% Convertible Notes for cash consideration of $24.8 million. 17. SHARE-BASED COMPENSATION Under the Company’s share-based compensation plans, the Company may issue up to 36,239,444 common shares on the exercise of stock options and in connection with the vesting of RSUs. Stock options and/or RSUs may be granted to eligible employees, officers, directors and consultants. The Company uses reserved and unissued common shares to satisfy its obligations under its share-based compensation plans. The following table summarizes the components and classification of share-based compensation expense related to stock options and RSUs: 2010 2009 2008 Stock options . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RSUs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $56,851 41,182 $2,613 3,000 $5,243 2,663 Stock-based compensation expense . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $98,033 $5,613 $7,906 Cost of goods sold(1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Research and development expenses(1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Selling, general and administrative expenses(1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Restructuring and other costs (as described in note 6) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 1,258 2,487 44,806 49,482 $ 525 726 4,362 — $ 581 871 6,454 — Stock-based compensation expense . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $98,033 $5,613 $7,906 (1) Includes the excess of the fair value of Biovail stock options and time-based RSUs over the fair value of the vested and partially vested Valeant stock options and time-based RSUs of $20.9 million (as described in note 3), which was recognized immediately as post-Merger compensation expense and allocated as follows: cost of goods sold ($0.4 million), research and development expenses ($0.4 million), and selling, general and administrative expenses ($20.1 million). The Company did not recognize any tax benefits for share-based compensation expense for the years ended December 31, 2010, 2009 or 2008. Treatment of Biovail Stock Options and RSUs Following the Merger In accordance with the Merger agreement, each unvested stock option and time-based RSU award held by Biovail employees with employment agreements accelerate and become 100% vested upon involuntary termination following the Merger. As of the Merger Date, the Company calculated incremental compensation expense of $9.6 million to reflect an increase in the fair value of the stock options and time-based RSUs held by Biovail employees with employment agreements due to the acceleration of the vesting condition. This amount was recognized over the requisite service period of the terminated employees, which ended prior to December 31, 2010. Unvested stock option awards held by Biovail employees without employment agreements are forfeited if the employee is involuntarily terminated following the Merger. As of the Merger Date, the Company reversed $0.5 million of previously recognized compensation expense related to unvested stock options held by terminated employees without employment agreements. Unvested time-based RSU awards held by such Biovail employees vest on a pro-rata basis if the employee is involuntarily terminated following the Merger. Accordingly, no additional compensation expense related to the pro-rata vesting of time-based RSUs was required to be recognized by the Company post-Merger. F-41 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 17. SHARE-BASED COMPENSATION (Continued) Prior to the completion of the Merger, the board of directors of Biovail resolved that each performance-based RSU award held by Biovail executive officers and selected employees would immediately accelerate and become 100% vested on the Merger Date. The number of such performance-based RSUs to be settled would be determined based on Biovail’s performance through the Merger Date. Based on such performance, each performance-based RSU vested upon the closing of the Merger at 200% of target. As of the Merger Date, the Company recorded incremental compensation expense of $20.3 million to reflect an increase in the fair value of the performance-based RSUs due to the acceleration of the vesting condition. The common shares of the Company underlying the performance-based RSUs were delivered, net of income tax withholdings, to the applicable employees within 60 days of the Merger Date. Treatment of Valeant Continuing Stock Options and RSUs Following the Merger As of the Merger Date, the Company recorded compensation expense of $20.1 million to reflect the acceleration of the vesting term related to stock options and RSUs held by former executive officers of Valeant. Upon the closing of the Merger, each outstanding Valeant stock option and RSU that did not provide for vesting was converted into an option or RSU to acquire or receive common shares of the Company, after taking account of the pre-Merger special dividend and the exchange ratio for the Merger, on the same terms and conditions as were applicable to the stock option or RSU prior to the Merger. Valeant stock option grants generally vested ratably over a four-year period from the date of grant and had a term not exceeding 10 years. Valeant RSU grants vested based on the satisfaction of service conditions or on both service conditions and either the achievement of certain stock price appreciation conditions or the achievement of certain strategic initiatives. In total, 12,464,417 Biovail stock options were issued to replace Valeant stock options, and respectively 2,217,003 and 1,211,833 time-based RSUs and performance-based RSUs of Biovail were issued to replace equivalent awards of Valeant. As described in note 3, the fair values of the vested portions of the Valeant stock options and Valeant RSUs were recognized as components of the purchase price or immediately as compensation expense as of the Merger Date. The following table summarizes the compensation cost and weighted-average service periods related to the unvested portions of the Valeant stock options and RSUs: Number of awards issued (000s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Total compensation cost related to unvested awards to be recognized . . . . . . . . . . . . . . . . Weighted-average service period over which compensation cost is expected to be recognized Stock Options Time- Based RSUs Performance- Based RSUs 12,464 $66,520 2,217 $30,558 1,212 $24,998 (months) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 25 34 Stock Options With the exception of Biovail stock options issued to replace Valeant stock options in connection with the Merger, all stock options granted by the Company expire on the fifth anniversary of the grant date. The exercise price of any stock option granted will not be less than the volume-weighted average trading price of the Company’s common shares for the five trading days immediately preceding the date of grant (or, for participants subject to U.S. taxation, on the single trading day immediately preceding the date of grant, whichever is greater). Prior to the Merger, stock option grants typically vested ratably on the first, second and third anniversaries of the stock option grant. Following the Merger, stock options granted will vest 25% on each of the first, second, third and fourth anniversaries from the date of grant. The fair values of all stock options granted during the years ended December 31, 2010, 2009 and 2008 were estimated as of the date of grant using the Black-Scholes option-pricing model with the following weighted-average assumptions: Expected stock option life (years)(1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Expected volatility(2) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Risk-free interest rate(3) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Expected dividend yield(4) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4.0 4.0 4.0 37.1% 45.2% 43.2% 1.5% 3.0% 1.6% 1.5% 14.6% 14.1% (1) Determined based on historical exercise and forfeiture patterns. (2) Determined based on historical volatility of the Company’s common shares over the expected life of the stock option. 2010 2009 2008 F-42 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 17. SHARE-BASED COMPENSATION (Continued) (3) Determined based on the rate at the time of grant for zero-coupon U.S. or Canadian government bonds with maturity dates equal to the expected life of the stock option. (4) Determined based on the stock option’s exercise price and expected annual dividend rate at the time of grant. The Black-Scholes option-pricing model used by the Company to calculate stock option values was developed to estimate the fair value of freely tradeable, fully transferable stock options without vesting restrictions, which significantly differ from the Company’s stock option awards. This model also requires highly subjective assumptions, including future stock price volatility and expected time until exercise, which greatly affect the calculated values. The following table summarizes stock option activity during the year ended December 31, 2010: Outstanding, January 1, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Conversion of Valeant awards Exercised . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Expired or forfeited . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Options (000s) 3,988 2,383 12,464 (5,587) (1,045) Outstanding, December 31, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12,203 Vested and exercisable, December 31, 2010 . . . . . . . . . . . . . . . . . . . . . . . 5,100 Weighted- Average Remaining Contractual Term (Years) Weighted- Average Exercise Price Aggregate Intrinsic Value $17.02 22.20 8.59 10.56 21.57 $11.99 $ 9.61 6.4 5.2 $198,945 $ 95,259 The weighted-average fair values of all stock options granted in 2010, 2009 and 2008 were $5.46, $0.92 and $1.07, respectively. The total intrinsic values of stock options exercised in 2010 and 2009 were $28.5 million and $0.2 million, respectively. Proceeds received on the exercise of stock options in 2010 and 2009 were $58.4 million and $0.9 million, respectively. No stock options were exercised in 2008. The following table summarizes non-vested stock option activity during the year ended December 31, 2010: Stock Weighted- Average Options Grant-Date Fair Value (000s) Non-vested, January 1, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Conversion of Valeant awards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Vested . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Forfeited . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,648 2,383 7,204 (3,873) (259) Non-vested, December 31, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7,103 $ 1.81 5.46 16.21 10.10 5.24 $12.96 As of December 31, 2010, the total remaining unrecognized compensation expense related to non-vested stock options amounted to $65.2 million, which will be amortized over the weighted-average remaining requisite service period of approximately 21 months. The total fair value of stock options vested in 2010 was $39.1 million (2009 — $3.1 million; 2008 — $8.4 million). F-43 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 17. SHARE-BASED COMPENSATION (Continued) The following table summarizes information about stock options outstanding and exercisable as of December 31, 2010: Range of Exercise Prices $2.90–$4.35 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $4.36–$6.54 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $6.63–$9.95 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $10.83–$16.25 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $17.00–$25.50 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $25.51–$25.78 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Weighted- Average Remaining Weighted- Average Contractual Exercise Life Price (Years) Exercisable (000s) Weighted- Average Exercise Price 1.6 6.6 5.3 7.9 2.5 4.5 6.4 $ 3.59 4.66 7.85 13.46 22.39 26.36 $11.99 10 2,371 1,089 867 663 100 5,100 $ 3.59 4.78 7.77 13.00 23.16 25.78 $ 9.61 Outstanding (000s) 10 3,989 1,437 4,555 819 1,393 12,203 RSUs With the exception of Biovail RSUs issued to replace Valeant RSUs in connection with the Merger, RSUs vest on the third anniversary date from the date of grant, unless provided otherwise in the applicable unit agreement, subject to the attainment of any applicable performance goals specified by the board of directors. If the vesting of the RSUs is conditional upon the attainment of performance goals, any RSUs that do not vest as a result of a determination that a holder of RSUs has failed to attain the prescribed performance goals will be forfeited immediately upon such determination. RSUs are credited with dividend equivalents, in the form of additional RSUs, when dividends are paid on the Company’s common shares. Such additional RSUs will have the same vesting dates and will vest under the same terms as the RSUs in respect of which such additional RSUs are credited. Unless provided otherwise in the applicable RSU agreement, the Company may, in lieu of all or a portion of the common shares which would otherwise be provided to a holder, elect to pay a cash amount equivalent to the market price of the Company’s common shares on the vesting date for each vested RSU. The amount of cash payment will be determined based on the average market price of the Company’s common shares on the vesting date. The Company’s current intent is to settle vested RSUs through the issuance of common shares. Time-Based RSUs Each vested RSU without performance goals (‘‘time-based RSU’’) represents the right of a holder to receive one of the Company’s common shares. The fair value of each RSU granted is estimated based on the trading price of the Company’s common shares on the date of grant. The following table summarizes non-vested time-based RSU activity during the year ended December 31, 2010: Time-Based RSUs (000s) Weighted- Average Grant-Date Fair Value Non-vested, January 1, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Conversion of Valeant awards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Reinvested dividend equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Vested . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Forfeited . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Non-vested, December 31, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379 214 2,217 82 (542) (137) 2,213 $11.71 15.19 26.35 27.78 21.36 17.24 $24.61 As of December 31, 2010, the total remaining unrecognized compensation expense related to non-vested time-based RSUs amounted to $28.0 million, which will be amortized over the weighted-average remaining requisite service period of approximately 18 months. The total fair value of time-based RSUs vested in 2010 was $11.6 million (2009 — $0.1 million; 2008 — $0.2 million). F-44 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 17. SHARE-BASED COMPENSATION (Continued) Performance-Based RSUs Each vested RSU with performance goals (‘‘performance-based RSU’’) represents the right of a holder to receive a number of the Company’s common shares up to a specified maximum. For performance-based RSUs issued prior to the Merger, performance was measured based on shareholder return relative to an industry comparator group. For performance-based RSUs issued subsequent to the Merger, performance is determined based on the achievement of certain share price appreciation conditions. If the Company’s performance is below a specified performance level, no common shares will be paid. The fair value of each performance-based RSU granted during the years ended December 31, 2010, 2009 and 2008 was estimated using a Monte Carlo simulation model, which utilizes multiple input variables to estimate the probability that the performance condition will be achieved. The fair values of performance-based RSUs granted prior to the Merger were estimated with the following weighted- average assumptions: 2010 2009 2008 Contractual term (years) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Expected Company share volatility(1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Average comparator group share price volatility(1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Risk-free interest rate(2) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4.6 5.0 5.0 43.2% 44.0% 42.9% 34.7% 35.9% 34.0% 3.0% 3.1% 2.4% (1) Determined based on historical volatility over the contractual term of the performance-based RSU. (2) Determined based on the rate at the time of grant for zero-coupon U.S. government bonds with maturity dates equal to the contractual term of the performance-based RSUs. The fair values of performance-based RSUs granted in the post-Merger period ended December 31, 2010 were estimated with the following assumptions: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Contractual term (years) Expected Company share volatility(1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Risk-free interest rate(2) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4.1 - 4.6 32.4% - 33.2% 1.2% - 2.3% (1) Determined based on historical volatility over the contractual term of the performance-based RSU. (2) Determined based on the rate at the time of grant for zero-coupon U.S. government bonds with maturity dates equal to the contractual term of the performance-based RSUs. The following table summarizes non-vested performance-based RSU activity during the year ended December 31, 2010: 2010 Non-vested, January 1, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Conversion of Valeant awards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Reinvested dividend equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Vested . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Forfeited . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Non-vested, December 31, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 676 1,386 1,212 102 (800) (80) 2,496 $18.94 14.52 52.72 30.42 19.57 17.82 $33.25 Performance- Based RSUs (000s) Weighted- Average Grant-Date Fair Value F-45 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 17. SHARE-BASED COMPENSATION (Continued) As of December 31, 2010, the total remaining unrecognized compensation expense related to the non-vested performance-based RSUs amounted to $35.0 million, which will be amortized over the weighted-average remaining requisite service period of approximately 24 months. A maximum of 5,732,365 common shares could be issued upon vesting of the performance-based RSUs outstanding as of December 31, 2010. DSUs Non-management directors receive an annual grant of DSUs, and may elect to receive all or part of their board and committee retainers in the form of DSUs. A DSU is a notional unit, equivalent in value to a common share. DSUs are credited with dividend equivalents, in the form of additional DSUs, when dividends are paid on the Company’s common shares. Directors may not receive any payment in respect of their DSUs until they cease to be a director of the Company. The amount of compensation deferred is converted into DSUs based on the volume-weighted average trading price of the Company’s common shares for the five trading days immediately preceding the date of grant (for directors subject to U.S. taxation, the calculation may be based on the greater of the five-day or one-day volume-weighted average trading price). The Company recognizes compensation expense throughout the deferral period to the extent that the trading price of its common shares increases, and reduces compensation expense throughout the deferral period to the extent that the trading price of its common shares decreases. Following the Merger, the DSUs previously granted to non-management directors who did not remain on the board of directors of the Company will be redeemed, entitling each departing director to a payment of the cash value of his DSUs. Prior to December 31, 2010, cash payments of $2.3 million were made to settle 84,888 DSUs, with another 218,123 DSUs valued at $6.2 million remaining to be settled. The following table summarizes DSU activity during the year ended December 31, 2010: Outstanding, January 1, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Reinvested dividend equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Settled for cash . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Outstanding, December 31, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Weighted- Average Grant-Date Fair Value $12.82 16.15 24.72 12.37 $14.43 DSUs (000s) 343 105 19 (85) 382 The Company recorded compensation expense related to DSUs of $8.5 million, $2.5 million and $1.1 million in 2010, 2009 and 2008, respectively. As of December 31, 2010 and 2009, the Company recognized liabilities related to its DSU plans of $11.5 million and $4.8 million, respectively, based on the trading price of the Company’s common shares at those dates. F-46 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 18. ACCUMULATED OTHER COMPREHENSIVE INCOME The components of accumulated other comprehensive income as of December 31, 2010 and 2009 were as follows: Balance, January 1, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Foreign currency translation adjustment . . . . . . . . . . . . . . . . . . . . . Reclassification to net income(1) . . . . . . . . . . . . . . . . . . . . . . . . . . Unrealized holding loss on auction rate securities . . . . . . . . . . . . . . . Net unrealized holding loss on available-for-sale securities . . . . . . . . . Reclassification to net income(2) . . . . . . . . . . . . . . . . . . . . . . . . . . Cumulative effect adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . Balance, December 31, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . Foreign currency translation adjustment . . . . . . . . . . . . . . . . . . . . . Unrealized holding gain on auction rate securities . . . . . . . . . . . . . . . Net unrealized holding gain on available-for-sale securities . . . . . . . . . Reclassification to net income(2) . . . . . . . . . . . . . . . . . . . . . . . . . . Balance, December 31, 2009 . . . . . . . . . . . . . . . . . . . . . . . . . . . . Foreign currency translation adjustment . . . . . . . . . . . . . . . . . . . . . Unrealized holding gain on auction rate securities . . . . . . . . . . . . . . . Net unrealized holding loss on available-for-sale securities . . . . . . . . . Reclassification to net loss(2) . . . . . . . . . . . . . . . . . . . . . . . . . . . . Unrealized Holding Loss on Auction Rate Securities Net Unrealized Holding Gain (Loss) on Available- For-Sale Securities $(2,825) — — (3,356) — 4,352 — (1,829) — 155 — 731 (943) — 554 — 389 $ 6,791 — — — (304) (3,712) (2,343) 432 — — 802 (1,003) 231 — — (321) — Foreign Currency Translation Adjustment $ 58,616 (32,378) 828 — — — — 27,066 17,220 — — — 44,286 54,640 — — — Total $ 62,582 (32,378) 828 (3,356) (304) 640 (2,343) 25,669 17,220 155 802 (272) 43,574 54,640 554 (321) 389 Balance, December 31, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 98,926 $ — $ (90) $ 98,836 (1) Included in foreign exchange and other. (2) Included in gain (loss) on investments, net (as described in note 20). Income taxes are not provided for foreign currency translation adjustments arising on the translation of the Company’s operations having a functional currency other than the U.S. dollar. Income taxes allocated to other components of other comprehensive income, including reclassification adjustments, were not material. 19. LOSS ON EXTINGUISHMENT OF DEBT The components of loss on extinguishment of debt for the year ended December 31, 2010 were as follows: Extinguishment of liability component of 5.375% Convertible Notes (as described in note 14) . . . . . . . . . . . . . . . . . . Cash settlement of written call options (as described in note 3) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Repayment of Term Loan B Facility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2010 $20,652 10,064 1,697 $32,413 F-47 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 20. GAIN (LOSS) ON INVESTMENTS, NET The components of gain (loss) on investments, net for the years ended December 31, 2010, 2009 and 2008 were as follows: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Loss on auction rate securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Gain on auction rate securities settlement Gain on disposal of investments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Impairment loss on equity securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Equity loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $(5,552) — — — — $ (5,210) 22,000 804 — — $(8,613) — 6,534 (1,256) (1,195) $(5,552) $17,594 $(4,530) 2010 2009 2008 21. INCOME TAXES The components of income (loss) before recovery of income taxes were as follows: Domestic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Foreign . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $(127,269) (108,994) $ (81,978) 256,933 $ (86,734) 213,638 2010 2009 2008 The components of provision for (recovery of) income taxes were as follows: $(236,263) $174,955 $126,904 2010 2009 2008 Current: Domestic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Foreign . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 5,860 21,473 27,333 $ — $ — 14,500 14,500 17,000 17,000 Deferred: Domestic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Foreign . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (49,820) (5,583) — (16,000) — (90,000) (55,403) (16,000) (90,000) $(28,070) $ (1,500) $(73,000) F-48 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 21. INCOME TAXES (Continued) The reported recovery of income taxes differs from the expected amount calculated by applying the Company’s Canadian statutory rate to income before recovery of income taxes. The reasons for this difference and the related tax effects are as follows: Income before recovery of income taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Expected Canadian statutory rate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $(236,263) $174,955 $126,904 30.6% 32.4% 33.3% 2010 2009 2008 Expected provision for (recovery of) income taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Non-deductible amounts: Amortization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Share-based compensation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Merger costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Acquired IPR&D . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Non-taxable gain on disposal of investments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Legal settlement costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Write-down of investments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Intangible asset impairments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Equity loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Changes in enacted income tax rates Canadian dollar foreign exchange gain for Canadian tax purposes . . . . . . . . . . . . . . . . . . . Change in valuation allowance related to U.S. operating losses . . . . . . . . . . . . . . . . . . . . . Change in valuation allowance on Canadian deferred tax assets and tax rate changes . . . . . . . Foreign tax rate differences . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Loss of U.S. state net operating losses Unrecognized income tax benefit of losses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Withholding taxes on foreign income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Alternative minimum and other taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (72,296) 56,685 42,259 18,304 8,024 7,124 5,661 (1,679) — — — — 880 3,358 45,483 (46,898) (36,649) 9,783 22,768 3,177 — 4,890 11,962 — — 21,063 (3,838) 2,944 1,690 — — 9,800 2,500 (26,000) (11,000) (99,045) — 25,496 3,450 1,877 916 11,800 — — — (2,174) 10,233 3,089 2,482 398 — — (90,000) (13,993) (92,581) — 44,380 2,886 — 8,221 $ (28,070) $ (1,500) $ (73,000) F-49 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 21. INCOME TAXES (Continued) The tax effect of major items recorded as deferred tax assets and liabilities is as follows: 2010 2009 Deferred tax assets: Tax loss carryforwards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Tax credit carryforwards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Scientific Research and Experimental Development pool . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Research and development tax credits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Provisions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Plant, equipment and technology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Deferred revenue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Deferred financing and share issue costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Share-based compensation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 272,172 36,160 66,577 66,201 100,320 33,736 27,888 65,620 9,783 15,694 $ 159,669 — 58,914 42,659 24,990 34,019 33,433 — — 5,014 Total deferred tax assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Less valuation allowance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 694,151 (186,399) 358,698 (153,955) Net deferred tax assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 507,752 204,743 Deferred tax liabilities: Intangible assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5.375% Convertible Notes(1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Prepaid expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,779,460 8,171 510 — Total deferred tax liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,788,141 53,906 15,622 1,434 981 71,943 Net deferred income taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $(1,280,389) $ 132,800 (1) In connection with the issuance of the 5.375% Convertible Notes in June 2009 (as described in note 14), the Company recognized a deferred tax liability of $14.6 million for the original basis difference between the principal amount of the 5.375% Convertible Notes and the value allocated to the liability component, which resulted in a corresponding reduction to the valuation allowance recorded against deferred tax assets. The recognition of the deferred tax liability and the corresponding reduction in the valuation allowance were recorded as offsetting adjustments to additional paid-in capital. In the years ended December 31, 2010 and 2009, the deferred tax benefit recognized in earnings as the debt discount was amortized or extinguished was offset by the deferred tax expense related to the corresponding realization of the deferred tax assets. The eventual payment of the U.S. dollar-denominated 5.375% Convertible Notes will likely result in a foreign exchange gain or loss for Canadian income tax purposes. The amount of this gain or loss will depend on the exchange rate between the U.S. and Canadian dollar at the time the Convertible Notes are paid. At December 31, 2010, the Company recognized a $3.1 million deferred tax liability (and corresponding reduction to the valuation allowance) related to the unrealized foreign exchange gain on the translation of the face value of the 5.375% Convertible Notes to Canadian dollars for Canadian income tax purposes of approximately $23.8 million. If all of the outstanding 5.375% Convertible Notes had been paid at December 31, 2010, one-half of this foreign exchange gain would be included in the Company’s Canadian taxable income, which would result in a corresponding reduction in the Company’s available Canadian operating losses and tax credit carryforward balances (with an offsetting reduction to the valuation allowance provided against those balances). However, the payment of the 5.375% Convertible Notes will not result in a foreign exchange gain or loss being recognized in the Company’s consolidated financial statements, as these statements are prepared in U.S. dollars. The realization of deferred tax assets is dependent on the Company generating sufficient domestic and foreign taxable income in the years that the temporary differences become deductible. A valuation allowance has been provided for the portion of the deferred tax assets that the Company determined is more likely than not to remain unrealized based on estimated future taxable income and tax planning strategies. In 2010, the valuation allowance increased by $32.4 million. The net increase in valuation allowance resulted from the limitation of the Company’s use of U.S. federal and state net operating losses resulting from the Merger ($45.5 million increase in the valuation allowance), and the impact of foreign exchange rates on the reported value in U.S. dollars of Canadian tax loss carryforwards, Investment Tax Credits (‘‘ITCs’’), and pooled Scientific Research and Experimental Development (‘‘SR&ED’’) expenditures offset by the partial recognition of future benefits of Canadian tax loss carryforwards, ITCs, and pooled SR&ED F-50 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 21. INCOME TAXES (Continued) expenditures of $46.9 million recognized to the extent of deferred tax liabilities arriving from the Merger. Given the Company’s history of pre-tax losses in Canada, the Company determined that forecasted taxable income was insufficient objective evidence to release the remaining valuation allowance against Canadian tax loss carryforwards, ITCs and pooled SR&ED expenditures. In 2009, the valuation allowance decreased by $3.2 million due mainly to the recognition of additional future benefits of U.S. tax loss carryforwards and the impact of a decrease in enacted income tax rates on the reported value of net deferred income taxes, partially offset by the impact of foreign exchange rate changes on the reported value in U.S. dollars of Canadian tax loss carryforwards, ITCs, and pooled SR&ED expenditures. As of December 31, 2010, the Company had accumulated losses of approximately $154.8 million (2009 — $123.6 million) available for federal and provincial purposes in Canada. As of December 31, 2010, the Company had approximately $66.2 million (2009 — $42.7 million) of unclaimed Canadian ITCs and U.S. research and development credits, which expire from 2020 to 2030. These losses and ITCs can be used to offset future years’ taxable income and federal tax, respectively. In addition, as of December 31, 2010, the Company had pooled SR&ED expenditures amounting to approximately $282.9 million (2009 — $271.0 million) available to offset against future years’ taxable income from its Canadian operations, which may be carried forward indefinitely. The valuation allowance against the Canadian deferred tax assets is $118.2 million (2009 — $133.7 million). As of December 31, 2010, the Company has accumulated tax losses of approximately $672.6 million (2009 — $335.0 million) for federal purposes in the U.S., including pre-acquisition losses arising from the Merger of $337.8 million, which expire from 2021 to 2028 of which $191.5 million is subject to a valuation allowance related to annual loss limitation restrictions. These losses can be used to offset future years’ taxable income. The losses are subject to annual limitations as a result of ownership changes that have occurred. A valuation allowance of $68.2 million has been provided on the U.S. losses as management does not believe it is more likely than not that the Company will realize the benefits of the remaining net deferred tax asset as of December 31, 2010. Included in the $672.6 million of tax losses is approximately $53.7 million of pre-acquisition losses arising from the Merger related to the exercise of non-qualified stock options and restricted stock awards. The Company accrues for U.S. tax on the unremitted earnings of its foreign subsidiaries that are owned by the Company’s U.S. subsidiaries. Prior to the Merger, the Company asserted that the unremitted earnings of its Barbados subsidiaries would be permanently reinvested. The Company discontinued making this assertion as of December 31, 2010, but such change did not affect the Company’s deferred tax liabilities since the Barbados earnings can be repatriated to Canada without incurring additional tax. The Company continues to assert that the unremitted earnings of its U.S. subsidiaries will be permanently reinvested and not repatriated to Canada. It is not practical to estimate the deferred tax liability related to such permanently reinvested U.S. earnings. As of December 31, 2010, the total amount of unrecognized tax benefits (including interest and penalties) was $110.9 million (2009 — $66.2 million), of which $75.9 million (2009 — $45.2 million) would affect the effective tax rate. In the year ended December 31, 2010, the Company recognized a $10.1 million (2009 — $1.0 million) increase and a $15.6 million (2009 — $1.5 million) net increase in the amount of unrecognized tax benefits related to tax positions taken in the current and prior years, respectively, which have resulted in a corresponding decrease in the valuation allowance against the net deferred tax asset. The Company recognizes interest accrued related to unrecognized tax benefits and penalties in the provision for income taxes. As of December 31, 2010, approximately $20.5 million (2009 — $14.2 million) was accrued for the payment of interest and penalties. In the year ended December 31, 2010, the Company recognized approximately $3.4 million (2009 — $2.0 million) in interest and penalties. The Company and one or more of its subsidiaries file federal income tax returns in Canada, the U.S., Barbados, and other foreign jurisdictions, as well as various provinces and states in Canada and the U.S. The Company and its subsidiaries have open tax years primarily from 1996 to 2009 with significant taxing jurisdictions including Barbados, Canada, and the U.S. These open years contain certain matters that could be subject to differing interpretations of applicable tax laws and regulations, and tax treaties, as they relate to the amount, timing, or inclusion of revenues and expenses, or the sustainability of income tax positions of the Company and its subsidiaries. Certain of these tax years are expected to remain open indefinitely. In 2010, the Internal Revenue Service continued the examination of Valeant’s consolidated tax returns for the 2007 and 2008 tax years, which the Company expects to resolve within the next 12 months. The Company has been informed that its wholly-owned U.S. subsidiary Biovail Americas Corporation will have its consolidated federal income tax return for its 2009 tax year audited. In 2010, the Canadian Revenue Agency (‘‘CRA’’) continued its audit of the Company’s 2005 and 2006 Canadian income tax returns, and claims for SR&ED expenditures and related ITCs for the 2006 and 2007 taxation years. The CRA has made a proposal for audit adjustments to the Company. The Company is reviewing the proposal and while the matter has not been settled, the Company has recorded a decrease in deferred tax assets (increase in liability for uncertain tax positions) and a corresponding decrease in the valuation allowance. The Company has submitted a notice of objection to the CRA revised proposal for adjustments related to its 2003 and 2004 tax years. In 2010, the CRA continued its audit of the Company’s 2007 and 2008 Canadian annual tax returns. As a result of audits and statutes of limitation the Company estimates that up to $4.0 million of its uncertain tax positions will be realized. It is otherwise not possible for the F-51 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 21. INCOME TAXES (Continued) Company to estimate a range of reasonably possible outcomes, or timing, of any adjustments to the total amount of uncertain tax benefits that may result from these audits. The following table presents a reconciliation of the beginning and ending amounts of unrecognized tax benefits: Balance, beginning of year . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Acquisition of Valeant . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Additions based on tax positions related to the current year . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Additions for tax positions of prior years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Reductions for tax positions of prior years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 66,200 18,916 10,133 15,608 — $63,700 — 1,000 3,400 (1,900) Balance, end of year . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $110,857 $66,200 2010 2009 The Company does not expect any significant change to the above unrecognized tax benefits during the next 12 months. Certain unrecognized tax benefits have been recorded as a reduction of deferred tax assets. 22. EARNINGS PER SHARE Earnings (loss) per share for the years ended December 31, 2010, 2009 and 2008 were calculated as follows: Net income (loss) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $(208,193) $176,455 $199,904 Basic weighted-average number of common shares outstanding (000s) . . . . . . . . . . . . . . . . Dilutive effect of stock options and RSUs (000s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195,808 — 158,236 274 159,730 — Diluted weighted-average number of common shares outstanding (000s) . . . . . . . . . . . . . . . 195,808 158,510 159,730 Basic and diluted earnings (loss) per share . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ (1.06) $ 1.11 $ 1.25 2010 2009 2008 In 2010, all stock options, RSUs and Convertible Notes were excluded from the calculation of diluted loss per share, as the effect of including them would have been anti-dilutive, as it would have reduced the loss per share. The potential dilutive effect of stock options, RSUs and Convertible Notes on the weighted-average number of common shares outstanding was as follows: Basic weighted-average number of common shares outstanding (000s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Dilutive effect of stock options and RSUs (000s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Dilutive effect of Convertible Notes (000s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2010 195,808 2,774 6,947 Diluted weighted-average number of common shares outstanding (000s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 205,529 As the Company’s current intent and policy is to settle the Convertible Notes using a net share settlement approach, only the common shares potentially issuable with respect to the excess conversion value of the Convertible Notes over their principal amount is considered as dilutive potential common shares for purposes of calculating diluted earnings per share. In 2009, the average conversion value of the 5.375% Convertible Notes was less than the related principal amount, and, accordingly, no common shares were assumed to be issued for purposes of calculating diluted earnings per share. In 2010, 2009 and 2008, stock options to purchase approximately 1,465,000, 2,950,000 and 4,540,000 weighted-average common shares, respectively, were not included in the computation of diluted earnings per share because the exercise prices of the options were greater than the average market price of the Company’s common shares and, therefore, the effect would have been anti-dilutive. F-52 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 23. SUPPLEMENTAL CASH FLOW DISCLOSURES Interest and income taxes paid during the years ended December 31, 2010, 2009 and 2008 were as follows: Interest paid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Income taxes paid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $37,719 26,300 $ 4,182 12,139 $ 459 6,738 2010 2009 2008 24. LEGAL PROCEEDINGS From time to time, the Company becomes involved in various legal and administrative proceedings, which include product liability, intellectual property, antitrust, governmental and regulatory investigations, and related private litigation. There are also ordinary course employment-related issues and other types of claims in which the Company routinely becomes involved, but which individually and collectively are not material. Unless otherwise indicated, the Company cannot reasonably predict the outcome of these legal proceedings, nor can it estimate the amount of loss, or range of loss, if any, that may result from these proceedings. An adverse outcome in certain of these proceedings could have a material adverse effect on the Company’s business, financial condition and results of operations, and could cause the market value of its common shares to decline. From time to time, the Company also initiates actions or files counterclaims. The Company could be subject to counterclaims or other suits in response to actions it may initiate. The Company cannot reasonably predict the outcome of these proceedings, some of which may involve significant legal fees. The Company believes that the prosecution of these actions and counterclaims is important to preserve and protect the Company, its reputation and its assets. In 2010, the Company reached agreements or agreements in principle to settle certain litigation matters as noted below. In connection with these agreements, the Company recognized a $52.6 million charge to legal settlements expense, of which $16.0 million was accrued as of December 31, 2010. Governmental and Regulatory Inquiries On May 16, 2008, Biovail Pharmaceuticals, Inc., the Company’s former subsidiary, entered into a written plea agreement with the U.S. Attorney’s Office (‘‘USAO’’) for the District of Massachusetts whereby it agreed to plead guilty to violating the U.S. Anti-Kickback Statute and pay a fine of $22.2 million. In addition, on May 16, 2008, the Company entered into a non-prosecution agreement with the USAO whereby the USAO agreed to decline prosecution of Biovail in exchange for continuing cooperation and in exchange for agreement to finalize a civil settlement agreement and pay a civil penalty of $2.4 million. The civil settlement agreement has now been signed and the related fine has been paid. A hearing before the U.S. District Court in Boston took place on September 14, 2009 and the plea was approved. In addition, as part of the overall settlement, Biovail entered into a Corporate Integrity Agreement (‘‘CIA’’) with the Office of the Inspector General and the Department of Health and Human Services on September 11, 2009. The CIA requires Biovail to have a compliance program in place and to undertake a set of defined corporate integrity obligations for a five-year term. The CIA also includes requirements for an independent review of these obligations. The first of such reviews was completed in January 2011. Failure to comply with the obligations under the CIA could result in financial penalties. Securities Litigation On June 22, 2010, a stockholder of Valeant filed a purported class action complaint in Superior Court for Orange County, California captioned Deckter v. Valeant Pharmaceuticals International, et al., Case No. 30-2010-383335-CU-BT-CXC, on behalf of himself and all other stockholders of Valeant against Valeant and eight of its directors (the ‘‘Deckter Action’’). On July 1, 2010, a stockholder of Valeant filed a purported class action complaint in Superior Court for Orange County, California captioned Pronko v. Valeant Pharmaceuticals International, et al., Case No. 30-2010-386784-CU-SL-CXC, on behalf of himself and all other stockholders of Valeant against Valeant and its directors (the ‘‘Pronko Action’’). On July 13, 2010, a stockholder of Valeant filed a purported class action complaint al., Case No. 30-2010-389330-CU-SL-CXC, on behalf of herself and all other stockholders of Valeant against Valeant and its directors (the ‘‘Martino Action’’). On July 14, 2010, a stockholder of Valeant filed a purported class action complaint in Superior Court for Orange County, California captioned Haro v. Pearson, et al., Case No. 30-2010-389773-CU-BT-CXC, on behalf of himself and all other stockholders of Valeant against Valeant, certain officers and directors of Valeant, Biovail, Biovail Americas Corp., a wholly-owned subsidiary of Biovail (‘‘BAC’’), and Beach Merger Corp., a wholly owned subsidiary of BAC (‘‘Merger Sub’’) (the ‘‘Haro Action’’). The for Orange County, California in Superior Court captioned Martino v. Pearson, et F-53 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 24. LEGAL PROCEEDINGS (Continued) complaints variously allege that the individual defendants, aided and abetted by Valeant, Biovail, BAC and Merger Sub, breached their fiduciary duties of care, loyalty, candor, good faith and independence to stockholders in connection with the Merger of Valeant with Biovail. The California Court consolidated the Deckter Action, the Pronko Action, the Martino Action and the Haro Action in a single action (the ‘‘California Action’’). On October 12, 2010, the California Action was dismissed without prejudice. On July 16, 2010, a stockholder of Valeant filed a purported class action complaint in the Court of Chancery for the State of Delaware (‘‘Court of Chancery’’) captioned Porto v. Valeant Pharmaceuticals International, et al., Case No. 5644, on behalf of himself and all other stockholders of Valeant against Valeant, Valeant’s directors, Biovail, BAC and Merger Sub (the ‘‘Porto Action’’). On July 21, 2010, a stockholder of Valeant filed a purported class action complaint in the Court of Chancery captioned Marion v. Pearson, et al., Case No. 5658, on behalf of himself and all other stockholders of Valeant against Valeant and its directors (the ‘‘Marion Action’’). On July 22, 2010, a stockholder of Valeant filed a purported class action complaint in the Court of Chancery captioned Soukup v. Valeant Pharmaceuticals International, et al., Case No. 5664, on behalf of himself and all other stockholders of Valeant against Valeant, Valeant’s directors, Biovail, BAC and Merger Sub (the ‘‘Soukup Action’’). The complaints variously allege that the individual defendants, aided and abetted by Valeant, Biovail, BAC and Merger Sub, breached their fiduciary duties of care, loyalty, candor, good faith and independence to stockholders in connection with the Merger of Valeant with Biovail. On July 28, 2010, the plaintiff in the Porto Action filed a motion for a preliminary injunction and a motion for expedited proceedings. On August 2, 2010, the Court of Chancery granted an order consolidating the Porto, Soukup and Marion Actions into a single action (the ‘‘Delaware Action’’). On August 3, 2010, the Court of Chancery conditionally certified the Delaware Action as a class action. On August 4, 2010, the plaintiffs in the Delaware Action filed a Verified Consolidated Class Action Complaint on behalf of the holders of the common stock of Valeant against Valeant, the directors of Valeant, BAC and Merger Sub (the ‘‘Consolidated Complaint’’). The Consolidated Complaint alleged that the directors of Valeant, aided and abetted by BAC and Merger Sub, breached their fiduciary duties of care, loyalty, candor and good faith to Valeant stockholders in connection with the proposed Merger of Valeant with Biovail. On September 16, 2010 the parties to the Delaware Action executed a Memorandum of Understanding (‘‘MOU’’) containing the terms for the parties’ agreement in principle to resolve the Delaware Action. In exchange for Valeant and Biovail’s supplemental disclosures in the definitive proxy statement disseminated to all holders of record of Valeant stock as of the close of business on August 18, 2010 and additional disclosures in a Current Report on Form 8-K filed with the U.S. Securities and Exchange Commission (the ‘‘SEC’’) on September 20, 2010, and subject to court approval, plaintiffs’ counsel agreed, on behalf of the class, to, among other things, the dismissal of all claims asserted in the Delaware Action and a release of claims related to the Merger on behalf of the putative class of Valeant stockholders. The MOU further provides that the plaintiffs’ counsel will petition the Court for an award of fees and expenses in the amount of $0.45 million. The defendants deny all allegations of wrongdoing. After a settlement agreement was executed between the parties in the Delaware Action pursuant to the terms of the MOU and the settlement was approved by the Court, the Court entered an Order and Final Judgment on January 24, 2011, dismissing the Delaware Action and Plaintiffs’ claims with prejudice pursuant to the terms of the parties’ Settlement Agreement, together with the accompanying documents and the MOU executed by the parties on September 16, 2010. The Court granted plaintiffs’ counsel petition for an award of fees and expenses in connection with the Delaware Action of $0.4 million in attorneys’ fees and expenses. Antitrust Several class action and individual action complaints in multiple jurisdictions were commenced jointly against Biovail, Elan Corporation plc (‘‘Elan’’) and Teva Pharmaceuticals Industries Ltd. (‘‘Teva’’) relating to two agreements: one between Biovail and Elan for the licensing of Adalat CC products from Elan, and the other between Biovail and Teva for the distribution of those products in the U.S. These actions were transferred to the U.S. District Court for the District of Columbia and Consolidated as Multidistrict Litigation No. 1515. The Multidistrict Litigation includes class action and non class action suits. The agreements in question have since been unwound in accordance with a consent decree between Elan and Biovail and the U.S. Federal Trade Commission. The Court granted plaintiffs’ motion for class certification on November 21, 2007 and certified a class of alleged ‘‘direct purchasers’’. On February 17, 2010, Biovail entered into a settlement with the nonclass or individual plaintiffs (the ‘‘Optouts’’). Pursuant to the terms of the settlement, Biovail paid a settlement amount, which was accrued through a charge to legal settlements expense as at December 31, 2009, and made no admission of wrongdoing. Elan and Teva have also settled with the Optouts. The Optout actions were dismissed on February 22, 2010. Teva and the class plaintiffs executed a settlement agreement, dated May 27, 2010. The Court approved the settlement on December 7, 2010. The Company and Elan also reached a settlement with the class plaintiffs on or about November 30, 2010 to settle all claims for an amount not material to the Company. The court approved the settlement on January 31, 2011, and the class action was dismissed with prejudice. F-54 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 24. LEGAL PROCEEDINGS (Continued) On April 4, 2008, a direct purchaser plaintiff filed a class action antitrust complaint in the U.S. District Court for the District of Massachusetts against Biovail, GlaxoSmithKline plc, and SmithKline Beecham Inc. (the latter two of which are referred to here as ‘‘GSK’’) seeking damages and alleging that Biovail and GSK took actions to improperly delay FDA approval for generic forms of Wellbutrin XL(cid:4). The direct purchaser plaintiff in the Massachusetts federal court lawsuit voluntarily dismissed its complaint on May 27, 2008, and shortly thereafter re-filed a virtually identical complaint in the U.S. District Court for the Eastern District of Pennsylvania. In late May and early June 2008, additional direct and indirect purchaser class actions were also filed against Biovail and GSK in the Eastern District of Pennsylvania, all making similar allegations. These complaints have now been consolidated, resulting in a lead direct purchaser and a lead indirect purchaser action. On September 10, 2008, Biovail and GSK filed motions to dismiss both the direct and indirect purchaser actions. Those motions were heard on February 26, 2009. In the direct purchaser case, on March 13, 2009, the Court granted in part and denied in part the motions, dismissing the Sherman Act Section 2 monopolization claim that had been made by the direct purchasers against Biovail. Biovail and GSK answered the remaining claims in the direct purchaser case on April 16, 2009. On March 26, 2009, before an order issued on the motions to dismiss the indirect purchaser plaintiffs’ claims, the indirect purchaser plaintiffs filed an amended complaint. The pending motions were therefore denied as moot, and new motions to dismiss the indirect purchaser plaintiffs’ claims were filed on April 30, 2009. On July 30, 2009, the Court dismissed all indirect purchaser claims except the antitrust claims (limited as to Biovail’s concerted actions) in California, Nevada, Tennessee and Wisconsin and the consumer protection claims of California and Florida. On May 13, 2010, Aetna, Inc. (‘‘Aetna’’) filed a motion to intervene as an indirect purchaser. The Court denied Aetna’s motion to intervene on July 21, 2010. Subsequently, the direct purchaser plaintiffs and Aetna Health of California Inc. filed a motion to substitute Aetna Health of California Inc. as the representative of the pending California claims on August 13, 2010. The Court granted this motion on September 22, 2010. Additionally, on September 14, 2010, the indirect purchaser plaintiffs filed a motion for leave to amend their complaint to add claims under Illinois’s Antitrust Act and New York’s Donnelly Act. The Company and GSK opposed the indirect purchaser plaintiffs’ motion. On December 21, 2010, the Court granted in part and denied in part the motion for leave to amend, permitting indirect purchasers leave to amend their complaint to assert claims under New York’s Donnelly Act but not under Illinois’s Antitrust Act. Plaintiffs have filed motions for class certification. The Company and GSK opposed the motions. A hearing on plaintiffs’ class certification motions is currently set for April 5, 2011. The deadline for fact discovery is currently April 29, 2011, with an August 26, 2011 deadline for expert discovery. The deadline for filing of motions for summary judgment is currently set for September 23, 2011, with a hearing set on such motions for December 2, 2011. The Company believes that each of these complaints lacks merit and that the Company’s challenged actions complied with all applicable laws and regulations, including federal and state antitrust laws, FDA regulations, U.S. patent law and the Hatch Waxman Act. Intellectual Property In August 2006, Sandoz Canada Inc. (‘‘Sandoz’’) brought an action against Biovail under section 8 of the Canadian Patented Medicines Notice of Compliance Regulations (‘‘PMNOC Regulations’’) demanding damages for having been kept off the market with its generic version of Tiazac(cid:4) due to prohibition proceedings taken against Sandoz’s predecessor RhoxalPharma Inc. by Biovail under the PMNOC Regulations. The prohibition proceedings were subsequently dismissed in November of 2005. The Company defended against the action and discovery had commenced. The matter was settled on January 25, 2011 for an amount that is not material to the Company, and the action was discontinued with prejudice on February 3, 2011. On January 18, 2010, a Canadian Federal Court judge presiding over Biovail and Depomed, Inc. (‘‘Depomed’’) v. Apotex Inc. (‘‘Apotex’’) et al. issued a decision in a proceeding pursuant to the PMNOC Regulations in Canada to determine whether Apotex’s allegations that a Depomed patent was invalid and/or not infringed was justified. This proceeding related to a Canadian application filed by Apotex to market a generic version of the 500mg formulation of Glumetza(cid:4) (extended release metformin hydrochloride tablets) licensed in Canada by Depomed to Biovail Laboratories International SRL (‘‘BLS’’). Pursuant to the decision issued by the Court, Health Canada can authorize Apotex to market in Canada its generic version of the 500mg formulation of Glumetza(cid:4). The decision, which was amended on January 20, 2010, found under Canadian law that Apotex’s allegation was justified that the Depomed Canadian patent at issue in the matter (No. 2,290,624) (the ‘‘‘624 Patent’’) is obvious. The judge found that the evidence presented by the parties was ‘‘evenly balanced’’ as to obviousness. The judge found in favour of Biovail and Depomed as to all other issues related to the ‘624 Patent under Canadian law. Apotex was authorized by Health Canada on February 4, 2010 to market its generic version of 500 mg Glumetza(cid:4) in Canada. This decision, however, did not find the patent invalid and does not preclude the filing of a subsequent patent infringement suit against Apotex. Biovail and Depomed commenced action for patent infringement against Apotex in Canadian Federal Court on February 8, 2010. Pleadings have now closed, but no further steps have yet been taken. F-55 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 24. LEGAL PROCEEDINGS (Continued) On or about June 24, 2010, Biovail and BLS received a Notice of Allegation from Mylan Pharmaceuticals ULC (‘‘Mylan’’) with respect to Bupropion Hydrochloride 150 mg and 300 mg tablets, marketed in Canada by Biovail as Wellbutrin(cid:4) XL. The patents in issue are Canadian Patent Nos. 2,142,320, 2,168,364 and 2,524,300. Mylan alleges that its generic form of Wellbutrin(cid:4) XL does not infringe the patents and, alternatively, that the patents are invalid. Following an evaluation of the allegations in the Notice of Allegation, an application for an order prohibiting the Minister from issuing a Notice of Compliance to Mylan was issued in the Federal Court on August 6, 2010, relating to Canadian Patent Nos 2,524,300 and 2,168,324. Mylan has now withdrawn its allegations of invalidity. The matter is proceeding in the ordinary course. In 2007, BLS, together with Purdue Pharma Products LP and Napp Pharmaceutical Group Ltd. (collectively ‘‘Purdue’’) and Ortho- McNeil, Inc. (‘‘OMI’’), filed suit in the U.S. District Court for the District of Delaware against Par Pharmaceutical Companies, Inc. (‘‘Par’’), after Par filed an Abbreviated New Drug Application (‘‘ANDA’’) to market a generic version of Ultram(cid:4) ER prior to the expiration of U.S. Patent No. 6,254,887 (‘‘the ‘887 patent’’) and U.S. Patent No. 7,074,430 (‘‘the ‘430 patent’’). The plaintiffs alleged that Par’s generic version of Ultram(cid:4) ER would infringe the ‘887 and ‘430 patents. Par filed counterclaims of noninfringement and patent invalidity, which the plaintiffs denied. In late 2008, BLS filed a voluntary motion for dismissal from the litigation against Par, which the court granted. Shortly thereafter, OMI was also dismissed and the case proceeded to trial between Purdue and Par. The dismissal of BLS and OMI did not substantively affect the case. The case between Purdue and Par went to trial in April 2009. On August 14, 2009, the court found in favour of Par, holding that while Par infringed the ‘887 and ‘430 patents, the asserted claims of the patents were invalid. Purdue subsequently appealed the decision to the U.S. Court of Appeals for the Federal Circuit. On June 3, 2010, the Federal Circuit issued a decision affirming the district court’s ruling of patent invalidity. Purdue did not appeal the Federal Circuit decision, ending the litigation between Purdue and Par. On November 16, 2009, Par announced that it had received final FDA approval of its 100 mg and 200 mg generic versions of Ultram(cid:4) ER and had begun marketing the products. Concurrently, Patriot Pharmaceuticals LLC, a wholly-owned subsidiary of Ortho- McNeil-Janssen Pharmaceuticals, Inc., launched the Company’s authorized generic versions of these two strengths of Ultram(cid:4) ER. While the litigation between Purdue and Par was pending, BLS received notices from four other generic drug companies that those companies had filed their own applications to market generic versions of Ultram(cid:4) ER prior to expiration of the ‘887 and ‘430 patents. In response, patent infringement suits were filed against each of the four companies. In 2008, BLS, Purdue and OMI filed suit against Impax Laboratories, Inc. (‘‘Impax’’) after Impax filed an ANDA to market a generic version of Ultram(cid:4) ER prior to expiration of the ‘887 and ‘430 patents. BLS later filed a voluntary motion for dismissal from the suit, which the court granted. OMI was also dismissed, and the case continued between Purdue and Impax. On November 18, 2009, the case was stayed pending the outcome of the appeal in the case against Par. On September 2, 2010, the district court entered a Stipulation and Order Regarding Dismissal of Suit, ending the litigation between Purdue and Impax. In September 2009, Purdue filed suit against Paddock Laboratories, Inc. (‘‘Paddock’’) after Paddock filed an ANDA to market a generic version of Ultram(cid:4) ER prior to expiration of the ‘887 and ‘430 patents. On August 2, 2010, the district court entered a Stipulation and Order Regarding Dismissal of Suit, ending the litigation between Purdue and Paddock. The Company was not a party to this litigation. In October 2009, Purdue filed suit against Cipher Pharmaceuticals Inc. (‘‘Cipher’’) after Cipher filed a NDA under Section 505(b)(2) of the Federal Food, Drug and Cosmetics Act to market a generic version of Ultram(cid:4) ER prior to expiration of the ‘887 and ‘430 patents. On December 30, 2009, the court entered a Joint Stipulated Order of Judgment, ending the litigation between Purdue and Cipher. The Company was not a party to this litigation. In January 2010, Purdue filed suit against Lupin Pharmaceuticals Inc. (‘‘Lupin’’) after Lupin filed an ANDA to market a generic version of Ultram(cid:4) ER prior to expiration of the ‘887 and ‘430 patents. On November 3, 2010, the court entered a Stipulation and Order Regarding Dismissal of Suit, ending the litigation between Purdue and Lupin. The Company was not a party to this litigation. BLS filed an ANDA with the FDA seeking approval to market venlafaxine hydrochloride extended release capsules equivalent to the 37.5, 75 and 150 mg doses of Effexor(cid:4) XR. On June 26, 2008, Wyeth Pharmaceuticals Inc. (‘‘Wyeth’’) filed a complaint against Biovail, Biovail Technologies Ltd. (‘‘BTL’’) and BLS in the U.S. District Court for the District of Delaware alleging infringement of U.S. Patent Nos. 6,274,171 B1, 6,403,120 and 6,419,958 B2 by the filing of the ANDA, thereby triggering a 30-month stay of the FDA’s approval of that application. On September 25, 2008, Biovail, BTL and BLS filed their Answer and Affirmative Defenses along with counterclaims of non-infringement and invalidity. Biovail and Wyeth executed a Settlement and Release Agreement on November 12, 2009 and, subsequently, BLS and Wyeth executed a license agreement as of January 28, 2010, whereby BLS can manufacture, import and sell venlafaxine hydrochloride extended release capsules with an effective date expected to be on or about June 1, 2011, subject to earlier launch in limited circumstances, but in no event earlier than January 1, 2011. BLS will pay Wyeth a royalty fee on the sale of its F-56 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 24. LEGAL PROCEEDINGS (Continued) venlafaxine hydrochloride extended release capsules under the license, computed as a percentage of net sales, as defined in the license agreement. The license royalty fee term begins with the license effective date and ends on the expiration of the Wyeth patents covered by the license agreement. BLS is solely responsible for manufacturing and marketing its venlafaxine hydrochloride extended release capsules. Since December 31, 2009, BLS has not commenced sales of its venlafaxine hydrochloride extended release capsules. The parties filed a Joint Motion to Enter Consent Judgment and to Enter Stipulated Order on March 9, 2010, which was entered by the Court on March 19, 2010. On or about June 26, 2008, BLS received Notices of Paragraph IV Certification from Sun Pharmaceutical Industries, Ltd., India (‘‘Sun’’) for diltiazem hydrochloride extended release capsules, 120 mg, 180 mg, 240 mg, 300 mg, and 360 mg strengths, a generic version of Cardizem(cid:4) CD. On August 8, 2008, BLS filed suit against Sun in the U.S. District Court of New Jersey alleging patent infringement of U.S. Patent Nos. 5,470,584, 5,286,497 and 5,439,689 pursuant to the provisions of the Hatch-Waxman Act. BLS also sought declaratory judgment of infringement for all three patents. These suits are expected to result in a 30-month stay of the FDA approval of the 120 mg, 180 mg, 240 mg and 300 mg strengths. The patents-in-suit were listed in the FDA’s Orange Book against the 360 mg strength after the filing of the complaint in this action. On September 30, 2008, Sun delivered its Answer and Counterclaim, which include declarations of non-infringement, invalidity and unenforceability as well as certain antitrust allegations. In resolving this dispute, BLS and Sun executed a Settlement Agreement and a License Agreement on March 9, 2010. The parties filed a Stipulation and Proposed Order of Dismissal on April 16, 2010, which was entered as an Order of Dismissal by the Court on April 19, 2010. Under the terms of the settlement and license agreements, which were submitted to the U.S. Federal Trade Commission and U.S. Department of Justice pursuant to Section 1112(a) of the Medicare Prescription Drug Improvement and Modernization Act of 2003, BLS has granted Sun, and its subsidiary Sun Pharma Global FZE, a non-exclusive license (without right to sublicense) to distribute various dosage strengths of Sun’s generic formulation of Cardizem(cid:4) CD in the U.S., upon receipt of regulatory approval from the FDA, subject to certain limitations on the sales quantities of the 360mg dosage strength, with reference to IMS Health prescription data. Sun will pay BLS a royalty based on net sales of the various dosage strengths of its generic formulation. The license term ends August 8, 2012 — the date the last Cardizem(cid:4) CD patent expires. BLS filed an ANDA with the FDA seeking approval to market Fenofibrate Tablets in 48 mg and 145 mg dosage sizes in the U.S. On November 3, 2008, Abbott and Laboratoires Fournier S.A. (‘‘Abbott parties’’) filed a complaint against Biovail and BLS in the U.S. District Court for the Northern District of Illinois alleging infringement of U.S. Patent Nos. 6,277,405, 7,037,529, and 7,041,319 by the filing of the ANDA, thereby triggering a 30-month stay of FDA’s approval of that application. This matter was transferred to the U.S. District Court for the District of New Jersey. On November 3, 2008, Elan Pharma International Ltd. (‘‘Elan’’) and Fournier Laboratories Ireland Ltd. (‘‘Elan parties’’) also filed a complaint against Biovail and BLS in the U.S. District Court for the District of New Jersey alleging infringement of U.S. Patent Nos. 5,145,684, 7,276,249 and 7,320,802 by the filing of the ANDA. The Answers and Counterclaims of the Company and BLS have been filed. No dates are set for a Markman hearing or trial. The matters are currently stayed through February 28, 2011 to allow the parties to conclude settlement discussions. On February 24, 2011, BLS and Valeant entered into settlement and license agreements with the Abbott parties and the Elan parties. The settlement and license agreements, which must be reviewed by the Federal Trade Commission and U.S. Department of Justice before the cases can be dismissed by the Court, will allow BLS to market its Fenofibrate Tablets in 48 mg and 145 mg dosage sizes in the U.S. at a defined point in the future, prior to expiration of the patents in the lawsuits. On or about December 1, 2008, the FDA accepted an ANDA filed by BLS seeking approval to market generic formulations of the 200 mg, 300 mg and 400 mg strengths of quetiapine fumarate extended release tablets (sold under the brand name Seroquel(cid:4) XR by AstraZeneca Pharmaceuticals LP (‘‘AstraZeneca’’)). On January 9, 2009, AstraZeneca and AstraZeneca UK Limited filed a complaint against Biovail, BLS and BTA Pharmaceuticals, Inc. (‘‘BTA’’) in the U.S. District Court for the District of New Jersey alleging infringement of U.S. Patent Nos. 4,879,288 (the ‘‘‘288 Patent’’) and 5,948,437 (the ‘‘‘437 Patent’’) by the filing of that ANDA, thereby triggering a 30-month stay of the FDA’s approval of that application. Answers and Counterclaims have been filed. A Markman hearing was held on November 22, 2010, in Trenton New Jersey. The Court’s claim construction ruling was entered on November 30, 2010, and was generally favorable to the Company. The Court’s ruling provides the Company with grounds for motions for summary judgment of non-infringement and invalidity of certain claims. Fact discovery and related proceedings remains ongoing. Dispositive motions are due July 22, 2011, Pretrial motions are due September 2, 2011, the pretrial hearing is set for September 26, 2011 and the trial will commence on October 3, 2011. On or about July 3, 2009, BLS received a Notice from Cary Pharmaceuticals Inc. (‘‘Cary’’), related to Cary’s NDA pursuant to Section 505(B)(2) for bupropion hydrochloride 450 mg extended-release tablets. The Certification references U.S. Patent No. 6,096,341, which is listed in the FDA’s Orange Book for the 150 mg and 300 mg dosage strength of Wellbutrin XL(cid:4), and No. 6,143,327, which is currently listed in the FDA’s Orange Book for the 150 mg dosage strength of Wellbutrin XL(cid:4). On August 13, 2009, Biovail filed suit in the U.S. District Court for the District of Delaware, thereby triggering a 30-month stay of the approval of Cary’s NDA. The Complaint F-57 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 24. LEGAL PROCEEDINGS (Continued) was served on Cary on August 24, 2009, and Cary served its Answer on September 24, 2009. On January 26, 2011, the case was terminated by agreement between the parties with a dismissal by the Company without prejudice. On or about January 5, 2010, BLS received a Notice of Paragraph IV Certification dated January 4, 2010 from Watson Laboratories, Inc. — Florida (‘‘Watson’’), related to Watson’s ANDA filing for Bupropion Hydrobromide Extended-release Tablets, 174 mg and 348 mg, which correspond to the Company’s Aplenzin(cid:4) Extended-release Tablets 174 mg and 348 mg products. Watson asserted that U.S. Patent Nos. 7,241,805, 7,569,610, 7,572,935 and 7,585,897 which are listed in the FDA’s Orange Book for Aplenzin(cid:4) are invalid or not infringed. BLS subsequently received from Watson a second Notice of Paragraph IV Certification for U.S. Patent Nos. 7,645,802 and 7,649,019, which were listed in the FDA’s Orange Book after Watson’s initial certification. Watson has alleged these patents are not infringed or invalid. BLS filed suit pursuant to the Hatch-Waxman Act against Watson on February 18, 2010, in the U.S. District Court for the District of Delaware and on February 19, 2010, in the U.S. District Court for the Southern District of Florida, thereby triggering a 30-month stay of the approval of Watson’s ANDA. The Delaware action has been dismissed without prejudice and the litigation is proceeding in the Florida Court. BLS received a third Notice of Paragraph IV Certification from Watson dated March 5, 2010, seeking to market its products prior to the expiration of U.S. Patent Nos. 7,662,407 and 7,671,094. BLS received a fourth Notice of Paragraph IV Certification from Watson on April 9, 2010. BLS filed a second Complaint against Watson in Florida Court on the third and fourth Notices on April 16, 2010. The two actions have been consolidated into the first-filed case before the same judge. In the course of discovery the issues have been narrowed and only five of the patents remain in the litigation. Mandatory mediation was completed unsuccessfully on December 17, 2010 and a trial is set to commence in June 2011. On or about January 27, 2010, BLS received a Notice of Paragraph IV Certification from Paddock dated January 22, 2010, relating to Paddock’s ANDA filing for Bupropion Hydrobromide Extended-release Tablets, 174 mg and 522 mg, which correspond to the Company’s Aplenzin(cid:4) Extended-release Tablets 174 mg and 522 mg products. Paddock has certified that the six patents currently listed in the FDA’s Orange Book for Aplenzin(cid:4), plus an additional unlisted BLS patent relating to bupropion hydrobromide, are not infringed and/or invalid. A Complaint was filed on March 9, 2010 against Paddock in the U.S. District Court for the District of Minnesota. A parallel suit in the U.S. District Court for the District of Delaware has been dismissed without prejudice. A second suit was filed in the U.S. District Court for the District of Minnesota on April 15, 2010 following a second Paragraph IV certification received from Paddock. Both cases, which are now consolidated before the same judge, are proceeding in the ordinary course. On or about August 20, 2010, Biovail and BLS received a Notice of Paragraph IV Certification from Par Pharmaceutical, Inc. dated August 18, 2010, related to Par’s ANDA filing for Bupropion Hydrobromide Extended Release Tablets, 174 mg and 348 mg, which corresponds to the Company’s Aplenzin(cid:4) Extended-release Tablets, 174 mg and 348 mg products. Par has certified that eight patents currently listed in the Orange Book for Aplenzin(cid:4) are invalid, unenforceable and or not infringed. A Complaint was filed against Par Pharmaceutical Companies, Inc. and Par Pharmaceutical, Inc. on September 22, 2010 in the U.S. District Court for the Southern District of New York. The case is proceeding in the ordinary course. On or about October 22, 2010, BTL Received a Notice of Paragraph IV Certification from Watson Laboratories, Inc. dated October 20, 2010 relating to U.S. Patent No. 7,815,937 (the ‘‘937 patent’’) which was issued on October 19, 2010 and is assigned to BLS. The Notice alleges that Watson’s ANDA for Lamotrigine Orally Disintegrating Tablets, 25 mg, 50 mg, 100 mg and 200 mg, which correspond to the Lamictal(cid:4) ODT(cid:5) (lamotrigine) Orally Disintegrating Tablets, 25 mg, 50 mg, 100 mg, and 200 mg of NDA holder SmithKline Beecham Corporation d/b/a/ GlaxoSmithKline does not infringe the ‘937 patent and/or the patent is invalid or unenforceable. Since the ‘937 patent is not listed in the Orange Book for Lamictal(cid:4) ODT(cid:5) (lamotrigine) Orally Disintegrating Tablets, the Company has taken no action. Biovail v. S.A.C. and Others; S.A.C. v. Biovail; Gradient Analytics v. Biovail On February 22, 2006, Biovail filed a lawsuit in Superior Court, Essex County, New Jersey, seeking $4.6 billion in damages from 22 defendants (the ‘‘S.A.C. Complaint’’). The S.A.C. Complaint alleges that the defendants participated in a stock market manipulation scheme that negatively affected the market price of the Company’s common shares and alleges violations of various state laws, including the New Jersey Racketeer Influenced and Corrupt Organizations Act. included: S.A.C. Capital Management, LLC, S.A.C. Capital Advisors, LLC, S.A.C. Capital The original defendants Associates, LLC, S.A.C. Healthco Funds, LLC, Sigma Capital Management, LLC, Steven A. Cohen, Arthur Cohen, Joseph Healey, Timothy McCarthy, David Maris, Gradient Analytics, Inc., Camelback Research Alliance, Inc., James Carr Bettis, Donn Vickrey, Pinnacle Investment Advisors, LLC, Helios Equity Fund, LLC, Hallmark Funds, Gerson Lehrman Group, Gerson Lehrman Group Brokerage Services, LLC, Thomas Lehrman, Patrick Duff and James Lyle. The defendant Hallmark Funds was voluntarily dismissed from the action by Biovail. On April 17, 2009, the Company filed a motion for leave to file a Second Amended Complaint, amending the allegations to assert trade libel and conspiracy, and seeking damages in excess of $100.0 million. The proposed Second Amended Complaint names as defendants F-58 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 24. LEGAL PROCEEDINGS (Continued) only the S.A.C. related entities, Timothy McCarthy and Gradient Analytics, LLC (formerly Camelback Research Alliance Inc.). All other remaining defendants were dismissed from the lawsuit. The named defendants opposed the filing of the Second Amended Complaint and moved to dismiss it. The motion was heard on July 10, 2009. A decision was subsequently rendered in the defendants’ favour on August 20, 2009. As a result, the matter was dismissed. On February 17, 2010, S.A.C. Capital Advisors, LLC commenced an action against Biovail in the United States District Court for the District of Connecticut. The complaint alleges malicious prosecution related to Biovail’s complaint against it. A factually similar complaint was filed the same day by Gradient Analytics, Inc., Donn Vickery and James Carleton Carr Bettis in the United States Court for the District of Arizona. Biovail believed that these complaints were without merit and filed motions to dismiss. On November 3, 2010, the Company entered into an agreement to settle the S.A.C. action, and on November 9, 2010, the Company entered an agreement with Gradient, Vickery and Bettis to settle the Gradient action. The amounts of the settlements were not material to the Company. Based upon the agreements to settle the S.A.C. action and the Gradient action, the lawsuits were dismissed with prejudice against the Company. General Civil Actions Complaints have been filed by the City of New York, the State of Alabama, the State of Mississippi and a number of counties within the State of New York, claiming that Biovail, and numerous other pharmaceutical companies, made fraudulent misstatements concerning the ‘‘average wholesale price’’ (‘‘AWP’’) of their prescription drugs, resulting in alleged overpayments by the plaintiffs for pharmaceutical products sold by the companies. The City of New York and plaintiffs for all the counties in New York (other than Erie, Oswego and Schenectady) have voluntarily dismissed Biovail and certain others of the named defendants on a without prejudice basis. Similarly, the State of Mississippi has voluntarily dismissed its claim against Biovail and a number of defendants on a without prejudice basis. In the case brought by the State of Alabama, the Company has answered the State’s Amended Complaint and discovery is ongoing. On October 16, 2009, the Supreme Court of Alabama issued an opinion reversing judgments in favour of the State in the first three cases that were tried against co-defendant companies. The Alabama Supreme Court also rendered judgment in favour of those defendants, finding that the State’s fraud-based theories failed as a matter of law. A trial date has not been set. The cases brought by the New York State counties of Oswego, Schenectady and Erie, each of which was originally brought in New York State court, were removed by defendants to Federal Court on October 11, 2006. Biovail answered the complaint in each case after the removal to Federal Court. The cases were subsequently remanded and, following the remand, the New York State Litigation Coordinating Panel granted the defendants’ application to coordinate the three actions for pretrial purposes in Erie County. The Company settled these cases, which will be dismissed with prejudice in the first quarter of 2011. The settlement amount payable is not material. A Third Amending Petition for Damages and Jury Demand was filed on November 10, 2010 in Louisiana State Court by the State of Louisiana claiming that a former subsidiary of the Company, and numerous other pharmaceutical companies, knowingly inflated the AWP and ‘‘wholesale acquisition cost’’ of their prescription drugs, resulting in alleged overpayments by the State for pharmaceutical products sold by the companies. The matter is in preliminary stages, the Company intends to defend against this action. On December 15, 2009, Biovail was served with a Seventh Amended Complaint under the False Claims Act in an action captioned United States of America, ex rel. Constance A. Conrad v. Actavis Mid-Atlantic, LLC, et al., United States District Court, District of Massachusetts. This case was originally filed in 2002 and maintained under seal until shortly before Biovail was served. Twenty other companies are named as defendants. In the Seventh Amended Complaint, Conrad alleges that various formulations of Rondec, a product formerly owned by Biovail, were not properly approved by the FDA and therefore not a ‘‘Covered Outpatient Drug’’ within the meaning of the Medicaid Rebate Statute. As such, Conrad alleges that Rondec was not eligible for reimbursement by federal healthcare programs, including Medicaid. Conrad seeks treble damages and civil penalties under the False Claims Act. According to the briefing schedule set by the court, motions to dismiss are due 30 days after the Complaint is unsealed in respect of each defendant. The Company intends to file a motion to dismiss. Legacy Valeant Litigation Valeant is the subject of a Formal Order of Investigation with respect to events and circumstances surrounding trading in its common stock, the public release of data from its first pivotal Phase III trial for taribavirin in March 2006, statements made in connection with the public release of data and matters regarding its stock option grants since January 1, 2000 and its restatement of certain historical financial statements announced in March 2008. In September 2006, Valeant’s board of directors established a Special Committee to F-59 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 24. LEGAL PROCEEDINGS (Continued) review its historical stock option practices and related accounting, and informed the SEC of these efforts. Valeant has cooperated fully and will continue to cooperate with the SEC in its investigation. The Company cannot predict the outcome of the investigation. On August 27, 2008, Valeant was served product liability complaints related to the pharmaceutical Permax in six separate cases by plaintiffs Prentiss and Carol Harvey; Robert and Barbara Branson; Dan and Mary Ellen Leach; Eugene and Bertha Nelson; Beverly Polin; and Ira and Michael Price against Eli Lilly and Company and Valeant Pharmaceuticals International in Superior Court, Orange County, California (the ‘‘California Permax Actions’’). The California Permax Actions were consolidated under the heading of Branson v. Eli Lilly and Company, et al. On May 5, 2010, Valeant reached an agreement in principle with plaintiffs to settle the California Permax Actions, and is in the process of finalizing settlement documentation for those matters. The portion of these settlements for which Valeant is responsible will not have a material impact on the Company’s financial results. On March 24, 2009, Valeant was named as a defendant in Edwin Elling v. Eli Lilly and Company, Valeant Pharmaceuticals International, Amarin Corporation, plc, Amarin Pharmaceuticals Inc., Elan Pharmaceuticals, Inc. and Athena Neurosciences, Inc. in the United Stated District Court for the Northern District of Texas, Ft. Worth Division; and Judith LaVois v. Eli Lilly and Company, Valeant Pharmaceuticals International, Amarin Corporation, plc, Amarin Pharmaceuticals Inc., Elan Pharmaceuticals, Inc., Athena Neurosciences, Inc. and Teva Pharmaceuticals USA, Inc. in the United States District Court for the Southern District of Texas, Houston Division. On January 15, 2010, Valeant reached an agreement in principle with plaintiffs to settle the Elling and LaVois matters, and the matters were dismissed on October 4, 2010 following final agreement on the settlement of the actions, which settlements did not have a material impact on the Company’s financial results. In addition to the lawsuits described above, Valeant has received, and from time to time receives, communications from third parties relating to potential claims that may be asserted with respect to Permax. On January 12, 2009, Valeant was served a complaint in an action captioned Eli Lilly and Company v. Valeant Pharmaceuticals International, Case No. 1:08-cv-1720-SEB-TAB in the U.S. District Court for the Southern District of Indiana, Indianapolis Division (the ‘‘Lilly Action’’). In the Lilly Action, Eli Lilly and Company (‘‘Lilly’’) brought a claim against Valeant for breach of contract and seeks a declaratory judgment arising out of a February 25, 2004 letter agreement between and among Lilly, Valeant and Amarin Corporation, plc related to cost-sharing for Permax product liability claims. On February 2, 2009, Valeant filed counterclaims against Lilly seeking a declaratory judgment and indemnification under the letter agreement. Valeant has responded to two motions for partial summary judgment brought by Lilly, and is in the process of defending the Lilly Action. Non-expert discovery closed on July 1, 2010, and expert discovery closed on September 15, 2010. On February 14, 2011, the court granted Lilly’s first motion for partial summary judgment declaring that cost-sharing obligations under the contract are based exclusively upon the date on which either party first receives written notice of such claim, regardless of Valeant’s dismissal or prevailing on the merits of a product liability claim, and that the costs of product liability claims to be shared by the parties include settlement costs, judgments, and the costs of defense incurred by Lilly and/or Valeant, including attorneys’ fees, expert fees, and expenses. The court’s order reserved ruling on whether the contract lacked consideration, government of the contract by the Uniform Commercial Code, reasonableness of non-joint representation counsel fees, and Valeant’s equitable defenses. On February 15, 2011, the court denied Lilly’s second motion for partial summary judgment holding that Valeant did not waive its right to recoup its own costs of defense, and is not barred from attempting to assert and set-off its defense costs. Trial is scheduled for April 2011. On or around January 19, 2009, Tolmar, Inc. (‘‘Tolmar’’) notified Galderma Laboratories, L.P. and Dow Pharmaceutical Sciences, Inc. (‘‘Dow’’) that it had submitted an ANDA, No. 090-903, with the FDA seeking approval for the commercial manufacture, use and sale of its Metronidazole Topical Gel, 1% (the ‘‘Tolmar Product’’) prior to the expiration of U.S. Patent Nos. 6,881,726 (the ‘‘‘726 patent’’) and 7,348,317 (the ‘‘‘317 patent). The ‘726 and ‘317 patents are owned by Dow, and licensed to Galderma. The ANDA contains a Paragraph IV certification alleging that the claims of the ‘726 and ‘317 patents will not be infringed by the manufacture, use, importation, sale or offer for sale of the Tolmar Product. On March 3, 2009, Galderma Laboratories, L.P., Galderma S.A., and Dow filed a complaint against Tolmar for the patent infringement of the ‘726 and ‘317 patents, pending in the United States District Court for the Northern District of Texas, Dallas Division. A Court-ordered preliminary mediation in the matter was conducted on October 13, 2010 and the parties were unable to reach any settlement. Galderma and Dow have served opposition to Tolmar’s Summary Judgment motion. A date for a hearing on the Summary Judgment motion has not been assigned by the Court. This lawsuit was filed within forty-five days of Tolmar’s Paragraph IV certification. As a result, The Hatch-Waxman Act provides an automatic stay on the FDA’s final approval of Tolmar’s ANDA for thirty months, which will expire in July 2011, or until a decision by the district court, whichever is earlier. 25. COMMITMENTS AND CONTINGENCIES Lease Commitments The Company leases certain facilities, vehicles and equipment principally under operating leases. Rental expense related to operating lease agreements amounted to $12.2 million, $4.8 million and $4.9 million in 2010, 2009 and 2008, respectively. F-60 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 25. COMMITMENTS AND CONTINGENCIES (Continued) Minimum future rental payments under non-cancelable operating leases for each of the five succeeding years ending December 31 and thereafter are as follows: Lease obligations . . . . . . . . . . . . . . . . . . . . . . . . . $94,277 $24,935 $12,148 $9,005 $6,869 $6,101 $35,219 Total 2011 2012 2013 2014 2015 Thereafter Other Commitments The Company had no material commitments related to capital expenditures as of December 31, 2010. Under certain research and development agreements, the Company may be required to make payments contingent upon the achievement of specific developmental, regulatory, or commercial milestones. As described in note 4, the Company may be required to make milestone payments of up to $55.0 million in the aggregate pursuant to the terms of the collaboration and license agreements for istradefylline. In addition, the Company assumed contingent milestone payments of Valeant of $412.2 million in the aggregate, including consideration of up to $390.0 million that it may be required to pay related to Valeant’s acquisition of Aton (as described in note 3). Indemnification Provisions In the normal course of business, the Company enters into agreements that include indemnification provisions for product liability and other matters. These provisions are generally subject to maximum amounts, specified claim periods, and other conditions and limits. As of December 31, 2010 or 2009, no material amounts were accrued for the Company’s obligations under these indemnification provisions. In addition, the Company is obligated to indemnify its officers and directors in respect of any legal claims or actions initiated against them in their capacity as officers and directors of the Company in accordance with applicable law. Pursuant to such indemnities, the Company is indemnifying certain former officers and directors in respect of certain litigation and regulatory matters. 26. SEGMENT INFORMATION Business Segments Effective with the Merger, the Company operates in the following business segments, based on differences in products and services and geographical areas of operations: • U.S. Neurology and Other consists of sales of pharmaceutical and OTC products indicated for the treatment of neurological and other diseases, as well as alliance revenue from the licensing of various products the Company developed or acquired. In addition, this segment includes revenue from contract research services provided by CRD prior to its disposal in July 2010. • U.S. Dermatology consists of pharmaceutical and OTC product sales, and alliance and contract service revenues in the areas of dermatology and topical medication. • Canada and Australia consists of pharmaceutical and OTC products sold in Canada, Australia and New Zealand. • Branded Generics — Europe consists of branded generic pharmaceutical products sold primarily in Poland, Hungary, the Czech Republic and Slovakia. • Branded Generics — Latin America consists of branded generic pharmaceutical and OTC products sold primarily in Mexico, Brazil and exports out of Mexico to other Latin American markets. Segment profit is based on operating income after the elimination of intercompany transactions. Certain costs, such as restructuring and acquisition-related costs and legal settlement and acquired IPR&D charges, are not included in the measure of segment profit, as management excludes these items in assessing financial performance. Corporate includes the finance, treasury, tax and legal operations of the Company’s businesses and maintains and/or incurs certain assets, liabilities, expenses, gains and losses related to the overall management of the Company, which are not allocated to the other business segments. In addition, share-based compensation is considered a corporate cost, since the amount of such expense depends on company-wide performance rather than the operating performance of any single segment. F-61 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 26. SEGMENT INFORMATION (Continued) Segment Revenues and Profit Segment revenues and profit for the years ended December 31, 2010, 2009 and 2008 were as follows: 2010 2009 2008 Revenues(1): U.S. Neurology and Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . U.S. Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Canada and Australia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Europe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Latin America . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 658,312 219,008 161,568 73,312 69,037 $ 575,321 146,267 83,959 14,883 — $ 525,939 150,613 73,764 6,862 — Total revenues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,181,237 820,430 757,178 Segment profit (loss)(2): U.S. Neurology and Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . U.S. Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Canada and Australia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Europe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Latin America . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251,129 47,737 51,043 20,646 (3,889) 274,548 87,860 35,037 9,152 — 243,180 93,475 15,171 3,553 — Total segment profit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366,666 406,597 355,379 Corporate(3) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Restructuring and other costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Acquired IPR&D . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Legal settlements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Acquisition-related costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Operating income (loss) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Interest income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Interest expense . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Write-down of deferred financing costs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Foreign exchange and other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Loss on early extinguishment of debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Gain (loss) on investments, net (155,794) (140,840) (89,245) (52,610) (38,262) (110,085) 1,294 (84,307) (5,774) 574 (32,413) (5,552) (124,269) (30,033) (59,354) (6,191) (5,596) 181,154 1,118 (24,881) (537) 507 — 17,594 (128,503) (70,202) — (32,565) — 124,109 9,400 (1,018) — (1,057) — (4,530) Income (loss) before recovery of income taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ (236,263) $ 174,955 $ 126,904 (1) Segment revenues in 2010 reflect incremental revenues from Valeant products and services commencing on the Merger Date as follows: U.S. Neurology and Other — $60.8 million; U.S. Dermatology — $57.2 million; Canada and Australia — $47.6 million; Branded Generics — Europe — $40.0 million; and Branded Generics — Latin America — $69.0 million. (2) Segment profit (loss) in 2010 reflects Valeant operations commencing on the Merger Date. Segment profit (loss) includes the impact of acquisition accounting adjustments related to the fair value adjustments to inventory and identifiable intangible assets as follows: U.S. Neurology and Other — $33.1 million; U.S. Dermatology — $27.4 million; Canada and Australia — $17.0 million; Branded Generics — Europe — $12.9 million; and Branded Generics — Latin America — $21.6 million. (3) Corporate reflects non-restructuring-related share-based compensation expense of $48.6 million, $5.6 million and $7.9 million in 2010, 2009 and 2008, respectively. F-62 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 26. SEGMENT INFORMATION (Continued) Segment Assets Total assets by segment as of December 31, 2010 and 2009 were as follows: Assets(1): U.S. Neurology and Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . U.S. Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Canada and Australia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Europe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Latin America . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 5,186,081 1,922,328 1,007,694 921,388 1,383,799 $1,553,652 169,164 76,739 11,560 — Corporate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10,421,290 373,827 1,811,115 248,175 Total assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $10,795,117 $2,059,290 2010 2009 (1) Segment assets as of December 31, 2010 reflect the provisional amounts of identifiable intangible assets and goodwill of Valeant as follows: U.S. Neurology and Other — $3,664.1 million; U.S. Dermatology — $1,711.8 million; Canada and Australia — $832.7 million; Branded Generics — Europe — $741.1 million; and Branded Generics — Latin America — $1,147.4 million. Capital Expenditures, and Depreciation and Amortization Capital expenditures, and depreciation and amortization by segment for the years ended December 31, 2010, 2009 and 2008 were as follows: Capital expenditures: U.S. Neurology and Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . U.S. Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Canada and Australia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Europe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Latin America . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Corporate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2010 2009 2008 $ 8,080 652 804 3,083 3,011 15,630 1,193 $ 6,098 — — — — 6,098 1,325 $ 8,112 — — 37 — 8,149 13,850 Total capital expenditures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 16,823 $ 7,423 $ 21,999 Depreciation and amortization(1): U.S. Neurology and Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . U.S. Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Canada and Australia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Europe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branded Generics — Latin America . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Corporate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $171,817 35,580 14,791 10,406 14,792 247,386 7,118 $110,876 23,981 5,707 — — 140,564 8,696 $ 64,160 23,928 5,219 — — 93,307 9,598 Total depreciation and amortization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $254,504 $149,260 $102,905 (1) Depreciation and amortization in 2010 reflects the impact of acquisition accounting adjustments related to the provisional fair value adjustment to identifiable intangible assets as follows: U.S. Neurology and Other — $15.4 million; U.S. Dermatology — $17.8 million; Canada and Australia — $6.7 million; Branded Generics — Europe — $6.7 million; and Branded Generics — Latin America — $12.1 million. F-63 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 26. SEGMENT INFORMATION (Continued) Geographic Information Revenues and long-lived assets by geographic region for the years ended and as of December 31, 2010, 2009 and 2008 were as follows: U.S. and Puerto Rico . . . . . . . . . . . . . . . . . . . . . . . . Canada . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Poland . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mexico . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Brazil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2010 $ 872,112 154,200 30,430 42,833 22,595 59,067 Revenues(1) 2009 $710,214 94,142 — — — 16,074 2008 $656,490 88,952 — — — 11,736 Long-Lived Assets(2) 2009 2008 2010 $ 14,231 94,435 60,390 51,367 46,074 15,255 $ 11,067 83,471 — — — 9,310 $ 31,377 107,918 — — — 8,974 (1) Revenues are attributed to countries based on the location of the customer. (2) Long-lived assets consist of property, plant and equipment, net of accumulated depreciation, which is attributed to countries based $1,181,237 $820,430 $757,178 $281,752 $103,848 $148,269 on the physical location of the assets. Major Customers External customers that accounted for 10% or more of the Company’s total revenues for the years ended December 31, 2010, 2009 or 2008 were as follows: McKesson Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cardinal Health, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AmerisourceBergen Corporation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Affiliates of Teva Pharmaceuticals Industries Ltd. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Affiliates of GSK . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Affiliates of Ortho-McNeil, Inc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2010 2009 2008 28% 25% 22% 24% 21% 16% 7% 12% 10% 7% 11% 6% 4% 16% 2% 5% 11% 2% 27. SUBSEQUENT EVENTS Acquisitions Cholestagel(cid:4) On February 9, 2011, the Company acquired the Canadian rights to Cholestagel(cid:4), an oral bile acid sequestrant for hypercholesterolemia, from Genzyme Corporation for a $2.0 million upfront payment, to be followed by potential additional milestone payments totaling up to $7.0 million. ACZONE(cid:4) On February 7, 2011, the Company entered into an agreement to license the Canadian rights to ACZONE(cid:4) Gel 5%, a topical formulation of dapsone used in the treatment of acne vulgaris, from Allergan, Inc. for an upfront payment of approximately $0.5 million and subsequent additional payments based on net sales. Zovirax(cid:4) On February 2, 2011, the Company entered into an asset purchase agreement to acquire U.S. rights to non-ophthalmic topical formulations of Zovirax(cid:4) from GSK. Following receipt of Hart-Scott-Rodino regulatory clearance, the Company closed the U.S. transaction on February 22, 2011. In addition, concurrent with the execution of the U.S. agreement, the Company entered into a binding letter of intent with GSK to acquire the Canadian rights to non-ophthalmic topical formulations of Zovirax(cid:4) and the Company is in the process of negotiating a definitive agreement for such acquisition. Pursuant to the terms of the asset purchase agreement, the Company paid to GSK an aggregate amount of $300.0 million in cash for both the U.S. and Canadian rights upon the closing of the F-64 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 27. SUBSEQUENT EVENTS (Continued) U.S. transaction. No additional payments will be made to GSK upon the closing of the Canadian transaction. The Company has been marketing Zovirax(cid:4) in the U.S. since January 1, 2002, under a 20-year exclusive distribution agreement with GSK, which distribution agreement terminated following the closing of the U.S. transaction. The Company has entered into a new supply agreement and a new trademark and domain name license agreement with GSK with respect to the U.S. territory. PharmaSwiss On January 31, 2011, the Company entered into a stock purchase agreement to purchase all of the issued and outstanding stock of PharmaSwiss S.A. (‘‘PharmaSwiss’’), a privately-owned branded generics and OTC pharmaceutical company based in Zug, Switzerland. The aggregate consideration payable is A350.0 million plus up to an additional A30.0 million in contingent payments if certain net sales milestones of PharmaSwiss are achieved for the calendar year ended 2011. The closing consideration is also subject to a working capital adjustment. PharmaSwiss is an existing partner to several large pharmaceutical and biotech companies offering regional expertise in such functions as regulatory, compliance, sales, marketing and distribution, in addition to developing its own product portfolio. Through its business operations, PharmaSwiss offers a broad product portfolio in seven therapeutic areas and operations in 19 countries throughout Central and Eastern Europe, including Poland, Hungary, the Czech Republic and Serbia, as well as in Greece and Israel. The transaction, which is subject to customary closing conditions, including certain regulatory approvals, is expected to close in the first quarter of 2011. 2021 Notes On February 8, 2011, Valeant issued at par $650.0 million aggregate principal amount of 6.75% Senior Notes due 2021 (the ‘‘2021 Notes’’) in a private placement. Interest on the 2021 Notes accrues at the rate of 6.75% and will be payable semi-annually in arrears on each February 15 and August 15, commencing on August 15, 2011. The 2021 Notes will mature of August 15, 2021. The 2021 Notes are the senior unsecured obligations of Valeant and are jointly and severally guaranteed on a senior unsecured basis by the Company and each of the Company’s subsidiaries (other than Valeant) that is a guarantor under its Credit Facilities (as described in note 14). Certain of the future subsidiaries of Valeant and the Company may be required to guarantee the 2021 Notes. The net proceeds of the 2021 Notes offering were to be used to finance the acquisition of PharmaSwiss and the acquisition of the U.S. and Canadian rights to Zovirax(cid:4) (as described above) (collectively, the ‘‘Acquisitions’’) and to pay fees and expenses in connection with the Acquisitions and for general corporate purposes. In accordance with the provisions of the 2021 Notes Indenture, pending the completion of the Acquisitions, Valeant deposited $400.0 million of the proceeds, together with cash in an amount sufficient to pay the special mandatory redemption price for the 2021 Notes being redeemed, plus accrued and unpaid interest to, but not including, the date of redemption, into an escrow account. Valeant granted the Trustee, for the benefit of the holders of the 2021 Notes, a lien on the funds held in the escrow account. On February 23, 2011, $135.0 million was released from escrow in connection with the completion of the acquisition of the U.S. rights to Zovirax(cid:4). If the proceeds of the 2021 Notes offering remaining in the escrow account are not released from escrow on or before March 25, 2011 (or June 24, 2011, if Valeant has obtained certain waivers to its Credit Agreement or if for any other reason, Valeant may maintain the funds in escrow without causing a default or an event of default under any of the covenants (financial or otherwise) in the Credit Agreement), then an aggregate principal amount of 2021 Notes equal to $265.0 million will be subject to a special mandatory redemption, on a pro-rata basis, at a price equal to 100% of the principal amount of the 2021 Notes being redeemed, plus accrued and unpaid interest to, but not including, the date of redemption. Additionally, if prior to March 25, 2011, Valeant has informed the escrow agent that it will not pursue the PharmaSwiss acquisition, then an aggregate principal amount of 2021 Notes equal to $265.0 million will be subject to a special mandatory redemption, on a pro-rata basis, at a price equal to 100% of the principal amount of the 2021 Notes being redeemed, plus accrued and unpaid interest to, but not including, the date of redemption. Valeant may redeem all or a portion of the 2021 Notes at any time prior to February 15, 2016, at a price equal to 100% of the principal amount thereof, plus accrued and unpaid interest, if any, to the date of redemption, plus a ‘‘make-whole’’ premium. On or after February 15, 2016, Valeant may redeem all or a portion of the 2021 Notes at the redemption prices applicable to the 2021 Notes as set forth in the 2021 Notes Indenture, plus accrued and unpaid interest to the date of redemption of the 2021 Notes. In addition, prior to February 15, 2014, Valeant may redeem up to 35% of the aggregate principal amount of the 2021 Notes with the net proceeds of certain equity offerings. F-65 VALEANT PHARMACEUTICALS INTERNATIONAL, INC. NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued) (All tabular dollar amounts expressed in thousands of U.S. dollars, except per share data) 27. SUBSEQUENT EVENTS (Continued) In the event of a Change of Control (as defined in the 2021 Notes Indenture), unless Valeant has exercised its right to redeem all of the 2021 Notes, each holder of the 2021 Notes may require Valeant to repurchase such holder’s 2021 Notes, at a purchase price equal to 101% of the principal amount thereof, plus accrued and unpaid interest to, but excluding, the purchase date. Share Repurchase Transaction On February 24, 2011, the Company entered into an agreement to repurchase 7,366,355 common shares from ValueAct Capital Master Fund, L.P. (‘‘ValueAct’’) for an aggregate purchase price of $275.0 million negotiated at a 5.77% discount over a 20-day trading day average, which was calculated in a similar manner to Valeant’s privately negotiated share repurchase from ValueAct completed in May 2010. The transaction, which is subject to closing conditions, is expected to be consummated on March 17, 2011, or such other time or date as the parties to the purchase agreement may agree. G. Mason Morfit is a partner and a member of the Management Committee of ValueAct Capital. Mr. Morfit joined the Company’s board of directors on September 28, 2010, effective with the Merger, and prior thereto served as a member of Valeant’s board of directors since 2007. ValueAct Capital is the general partner and the manager of ValueAct. F-66 JMS Job Number: 11-2428-3 File: DISK130:[11ZAE3.11ZAE72803]2428-3-KS_ZAE72803.CHC EFW: 2202280 User: RMCIVOR Printed: 28-Feb-2011;10:48:17 Created: Feb 28 06:38 2011 Client: VALEANT PHARMACEUTICALS (v.220) Chksum: 17689 HTML Page: 1 Folio: Doc # 12 Exhibit 23.1 Consent of Independent Registered Public Accounting Firm We consent to the incorporation by reference in the Registration Statement (Form S-8 No. 333-92229) pertaining to the 1993 Stock Option Plan and the 1996 Employee Stock Purchase Plan, in the Registration Statement (Form S-8 No. 333-138697) pertaining to the 2006 Stock Option Plan, in the Registration Statement (Form S-8 No. 333-168629) as filed on August 6, 2010 pertaining to the 2007 Equity Compensation Plan of Valeant Pharmaceuticals International, Inc., formerly Biovail Corporation, and in the Registration Statement (Post-Effective Amendment No. 1 on Form S-8 to Form S-4 No. 333-168254) pertaining to the equity originally issued under the Valeant Pharmaceuticals International 2006 Equity Incentive Plan and the Valeant Pharmaceuticals International 2003 Equity Incentive Plan, of our reports dated February 28, 2011, with respect to the consolidated financial statements and schedule of Valeant Pharmaceuticals International, Inc., and the effectiveness of internal control over financial reporting of Valeant Pharmaceuticals International, Inc., included in this Annual Report (Form 10-K) for the year ended December 31, 2010. Toronto, Canada February 28, 2011 /s/ ERNST & YOUNG LLP Chartered Accountants Licensed Public Accountant JMS Job Number: 11-2428-3 File: DISK130:[11ZAE3.11ZAE72803]2428-3-MA_ZAE72803.CHC User: RMCIVOR EFW: 2202280 Printed: 28-Feb-2011;10:48:17 Created: Feb 26 13:11 2011 Client: VALEANT PHARMACEUTICALS (v.220) Chksum: 279573 HTML Page: 1 Folio: Doc # 13 Exhibit 31.1 CERTIFICATION OF CHIEF EXECUTIVE OFFICER PURSUANT TO RULE 13a-14(a) AS ADOPTED PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002 I, J. Michael Pearson, certify that: 1. I have reviewed this annual report on Form 10-K of Valeant Pharmaceuticals International, Inc. (the “Company”); 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report; 3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the Company as of, and for, the periods presented in this report; 4. The Company’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the Company and have: (a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the Company, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared; (b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles; (c) Evaluated the effectiveness of the Company’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and (d) Disclosed in this report any change in the Company’s internal control over financial reporting that occurred during the period covered by the Company’s fourth fiscal quarter that has materially affected, or is reasonably likely to materially affect, the Company’s internal control over financial reporting; and 5. The Company’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the Company’s auditors and the audit committee of the Company’s board of directors: (a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the Company’s ability to record, process, summarize and report financial information; and (b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the Company’s internal control over financial reporting. Date: February 28, 2011 /s/ J. MICHAEL PEARSON J. Michael Pearson Chief Executive Officer JMS Job Number: 11-2428-3 File: DISK130:[11ZAE3.11ZAE72803]2428-3-MC_ZAE72803.CHC EFW: 2202280 User: RMCIVOR Printed: 28-Feb-2011;10:48:17 Created: Feb 26 13:11 2011 Client: VALEANT PHARMACEUTICALS (v.220) Chksum: 991668 HTML Page: 1 Folio: Doc # 14 Exhibit 31.2 CERTIFICATION OF CHIEF FINANCIAL OFFICER PURSUANT TO RULE 13a-14(a) AS ADOPTED PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002 I, Philip W. Loberg, certify that: 1. I have reviewed this annual report on Form 10-K of Valeant Pharmaceuticals International, Inc. (the “Company”); 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report; 3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the Company as of, and for, the periods presented in this report; 4. The Company’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the Company and have: (a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the Company, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared; (b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles; (c) Evaluated the effectiveness of the Company’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and (d) Disclosed in this report any change in the Company’s internal control over financial reporting that occurred during the Company’s fourth fiscal quarter that has materially affected, or is reasonably likely to materially affect, the Company’s internal control over financial reporting; and 5. The Company’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the Company’s auditors and the audit committee of the Company’s board of directors: (a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the Company’s ability to record, process, summarize and report financial information; and (b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the Company’s internal control over financial reporting. Date: February 28, 2011 /s/ PHILIP W. LOBERG Philip W. Loberg Executive Vice President, Interim Chief Financial Officer JMS Job Number: 11-2428-3 File: DISK130:[11ZAE3.11ZAE72803]2428-3-ME_ZAE72803.CHC EFW: 2202280 User: RMCIVOR Printed: 28-Feb-2011;10:48:17 Created: Feb 26 13:12 2011 Client: VALEANT PHARMACEUTICALS (v.220) Chksum: 1016540 HTML Page: 1 Folio: Doc # 15 Exhibit 32.1 CERTIFICATION OF THE CHIEF EXECUTIVE OFFICER PURSUANT TO 18 U.S.C. § 1350 AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 I, J. Michael Pearson, Chief Executive Officer of Valeant Pharmaceuticals International, Inc. (the “Company”), certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that, to my knowledge: 1. The Annual Report of the Company on Form 10-K for the fiscal year ended December 31, 2010 (the “Annual Report”) fully complies with the requirements of Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934; and 2. The information contained in the Annual Report fairly presents, in all material respects, the financial condition and results of operations of the Company. Date: February 28, 2011 /s/ J. MICHAEL PEARSON J. Michael Pearson Chief Executive Officer This certification accompanies the Annual Report pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 and shall not, except to the extent required by such Act, be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). Such certification will not be deemed to be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except to the extent that the Company specifically incorporates it by reference. A signed original of this written statement required by Section 906 has been provided to the Company and will be retained by the Company and furnished to the U.S. Securities and Exchange Commission or its staff upon request. JMS Job Number: 11-2428-3 File: DISK130:[11ZAE3.11ZAE72803]2428-3-MG_ZAE72803.CHC User: RMCIVOR EFW: 2202280 Printed: 28-Feb-2011;10:48:17 Created: Feb 26 13:12 2011 Client: VALEANT PHARMACEUTICALS (v.220) Chksum: 725546 HTML Page: 1 Folio: Doc # 16 Exhibit 32.2 CERTIFICATION OF THE CHIEF FINANCIAL OFFICER PURSUANT TO 18 U.S.C. § 1350 AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 I, Philip W. Loberg, Executive Vice President, Interim Chief Financial Officer of Valeant Pharmaceuticals International, Inc. (the “Company”), certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that, to my knowledge: 1. The Annual Report of the Company on Form 10-K for the fiscal year ended December 31, 2010 (the “Annual Report”) fully complies with the requirements of Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934; and 2. The information contained in the Annual Report fairly presents, in all material respects, the financial condition and results of operations of the Company. Date: February 28, 2011 By /s/ PHILIP W. LOBERG Philip W. Loberg Executive Vice President, Interim Chief Financial Officer This certification accompanies the Annual Report pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 and shall not, except to the extent required by such Act, be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). Such certification will not be deemed to be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except to the extent that the Company specifically incorporates it by reference. A signed original of this written statement required by Section 906 has been provided to the Company and will be retained by the Company and furnished to the U.S. Securities and Exchange Commission or its staff upon request. LAST PAGE OF FINANCIALS Board of Directors J. Michael Pearson Chairman and Chief Executive Officer, Valeant Pharmaceuticals International, Inc. Robert A. Ingram Lead Director, Valeant Pharmaceuticals International, Inc. Partner, Hatteras Venture Partners Committees: Nominating and Corporate Governance Theo Melas-Kyriazi Chief Financial Officer, Levitronix LLC Committees: Risk and Compliance (Chairperson), Finance and Audit, Transactions G. Mason Morfit Partner, ValueAct Capital Committees: Nominating and Corporate Governance (Chairperson), Compensation, Transactions Dr. Laurence E. Paul Founding Principal, Laurel Crown Capital LLC Committees: Transactions (Chairperson), Risk and Compliance Robert N. Power Corporate Director Committees: Compensation (Chairperson), Nominating and Corporate Governance Norma A. Provencio President and Owner, Provencio Advisory Services Inc. Committees: Special Committee (Chair- person), Finance and Audit, Compensation Lloyd M. Segal General Partner, Persistence Capital Partners Committees: Nominating and Corporate Governance, Transactions Katharine B. Stevenson Corporate Director Committees: Finance and Audit, Risk and Compliance Annual Meeting The Annual Meeting of Shareholders will be held at 10:00 a.m. EDT, May 16, 2011 at the Loews Hotel Vogue: Michael R. Van Every Retired Partner of Price Waterhouse Coopers LLP Committees: Finance and Audit (Chair- man), Risk and Compliance, Special 1425, rue de La Montagne Montréal Quebec. H3G 1Z3 All shareholders are welcome. Management Team J. Michael Pearson Chairman and Chief Executive Officer Rajiv De Silva President, Valeant Pharmaceuticals International, Inc. and Chief Operating Officer, Specialty Pharmaceuticals Robert Chai-Onn Executive Vice President, General Counsel and Corporate Secretary Philip W. Loberg Executive Vice President, Interim Chief Financial Officer Richard K. Masterson President and Chief Opperating Officer of Valeant International (Barbados) SRL Mark Durham Senior Vice President, Human Resources Corporate Information Corporate Headquarters 7150 Mississauga Road Mississauga, Ontario L5N 8M5 Phone: 905 286 3000 Fax: 905 286 3050 www.valeant.com Independent Auditors PricewaterhouseCoopers LLP Toronto, Ontario, Canada Investor and Media Relations You may request a copy of documents at no cost by contacting: Laurie W. Little Vice President, Investor Relations (949) 461-6002 ir@valeant.com Email updates are also available through the Investor Relations page at Valeant’s website. Stock Exchanges New York Stock Exchange and Toronto Stock Exchange NYSE/TSX Trading Symbols Common Stock: VRX Principal Transfer Agent & Registrar Valeant Pharmaceuticals International, Inc.’s designated transfer agent is CIBC Mellon Trust Company. The transfer agent is responsible for maintaining all records of registered stockholders (including change of address, telephone number, and name), canceling or issuing stock certificates and resolving prob- lems related to lost, destroyed or stolen certificates. If you are a registered stockholder of Valeant Pharmaceuticals International, Inc. and need to change your records pertaining to stock, please contact the Transfer Agent listed below: CIBC Mellon Trust Company 320 Bay St. Toronto, ON M5H 4A6 Phone 1-800-387-0825 / 416-643-5500 Website www.cibcmellon.com 7150 Mississauga Road Mississauga, Ontario L5N 8M5 Phone: 905 286 3000 Fax: 905 286 3050 www.valeant.com 

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