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Bio-Rad Laboratories

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FY2008 Annual Report · Bio-Rad Laboratories
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i s e x c e lli n g,

Business as Usual.

Bio-Rad Laboratories
Annual Report 2008

David Schwartz 

Norman Schwartz 

CHAiRmAN of tHe BoARD

PReSiDeNt

Let ter  t o Sh ar eh oLderS

Dear Shareholders,
As we look back, 2008 was a turbulent year for some other companies 
and for the financial markets, but was a fairly uneventful and rewarding 
year for us. Sales grew 21% to reach $1.7 billion, led by the acquisition  
of DiaMed in the fourth quarter of 2007. Underlying this acquired growth 
and some currency tailwinds, is good solid organic growth.
This is the core of Bio-Rad and the focus of our attention. While the year was relatively calm for 
us, it was another year of progress. Much of the effort has been centered around the successful 
integration of DiaMed and its well respected line of products for blood typing. Management is in 
place, progress is being made to bring their financial practices up to our standards and we are 
working on integrating several of the key independent distributors into our direct sales model. 
This work will continue into 2009, but we are pleased with what we have accomplished to date.

Both of our core business areas 

coming years. Our growth and 

While we are cautious about the 

made progress, not only in sales 

accomplishment brought us to 

next 12 to 18 months, we are not 

and profits, but in the introduction 

an additional milestone this year 

without optimism. The fundamentals 

of new products. Notable among 

as we moved to the New York 

of the company are strong. We en-

them, the development of a new line 

Stock Exchange.

joy a good reputation for quality and 

of thermal cyclers to address the 

important area of DNA amplifica-

tion, and the introduction of several 

new assays for the BioPlex® 2200 

clinical analyzer. In total, more than 

40 new products were introduced 

during the year. Operationally, we 

completed expansions of two of 

our European-based manufactur-

ing facilities and this year marked 

the first anniversary of the opening 

of our Singapore manufacturing 

site, which is doing well. In the early 

months of 2009, we will start up our 

new Shanghai-based R&D facility. 

While all of our geographic regions 

contributed to growth in 2008, 

the progress we are making in the 

Eastern European, Asia Pacific, and 

Latin American markets is outstand-

ing. The expectation is that these 

will continue to drive growth in the 

I am sure most messages to share-

holders this year from other com-

panies will make some reference to 

the financial market meltdown that 

erupted in September and caught 

most of us by surprise. Through 

the end of the year, this has had 

relatively little effect on our busi-

ness. Our life science and clinical 

diagnostics markets tend to be fairly 

stable and predictable and have 

continued to show promise. We 

innovation in our markets, markets 

that are fairly insulated from eco-

nomic perturbations. Our balance 

sheet is healthy and we generate 

good cash flow. Most important, we 

have a good pipeline of new prod-

ucts. These should all help us to 

navigate 2009 and beyond. Thank 

you for your continued interest and 

support of Bio-Rad.

are, nevertheless, moving forward 

David Schwartz 

with some caution. While there is 

Chairman of the BoarD

an expectation that the stimulus 

programs being put in place around 

the world may provide funds to gov-

ernment sponsored research, the 

net effects of this stimulus have yet 

to be determined. Some segments 

may also experience a moderation 

in healthcare spending, which we 

are closely monitoring.

norman Schwartz 

PreSiDent

page : 1

Bio-Rad Laboratories  |  Annual Report 2008 
If there’s one thing that companies 
want never to change in their business 
operations, it’s the steady march of 
successful best practices. A march 
fueled not only by innovation, creativity, 
and vision, but also by the ongoing, 
continuous behaviors that embody what 
has always been best about the company.

In 2008, Bio-Rad extended its track 
record of delivering ongoing improvement 
in virtually every area of the company, 
with another year of ...

Bio-Rad Laboratories  |  Annual Report 2008

  Business as Usual.

Success

  Business as Usual.

At the heArt of every 
Bio-rAd trAnsAction, 
there’s A customer  
with A nAme.

the very “Best” of A B usiness’s 

Best prActices is A simple one:   

listening. At Bio-rAd, we pride 

ourselves on getting to know 

our customers, And on under-

stAnding whAt’s importAnt to 

them. we then ensure thAt their 

desires Are incorporAted into 

our product development cycle. 

4 : page

Pe rs on a li zi n g
  Business as Usual.

Bio-Rad Laboratories  |  Annual Report 20086 : page

PerSonaLizing  buSi neSS aS uSu aL

For over half a century, Bio-Rad’s commitment to developing 
strong, long-lasting relationships with our customers has  
been one of our defining characteristics.
For us, it’s always personal. From pre-sale introductions to post-sale customer support, 
we place our focus on satisfying the needs of individual diagnosticians and researchers. 
Sales are the result of establishing and nurturing these relationships, but there are other 
rewards as well. Having direct, personal contact with our customers provides us with a 
better understanding of their workflows and how they define success. 

By combining a technical knowl-

Our current line of thermal cyclers 

Our commitment to our customers 

edge of our products with our 

has also benefited from this cus-

extends beyond the lab to more 

customers’ experiences, we are 

tomer-centric approach to product 

practical matters such as faster 

better able to develop innovative 

development. From our observation 

product delivery time, lower prices, 

products and make enhancements 

of customers at their bench and 

and technical support. Having a 

to current ones. This continual 

extensive usability testing on proto-

direct selling approach means 

feedback model encourages our 

types to real-time customer feed-

we must be as physically close 

entire organization to do more than 

back in online discussion groups, 

to our customers and markets as 

simply sell Bio-Rad products, it 

we’ve developed a product line that 

possible in order to serve them 

helps us to learn as much as we 

is defined by how it contributes to 

well. Since we opened our first 

can from our customers regarding 

their success.

what works and what could use 

some improvement. 

This philosophy of customer 

intimacy applies equally on our 

This customer-centric approach 

clinical diagnostics side. When we 

requires more of an investment on 

introduced a new test for MRSA 

our part, but we believe it’s worth 

(methicillin-resistant Staphylococ-

it. Our success over the years has 

cus aureus), a customer suggested 

proved that to be the case.   

that reading test results at exactly 

international office in Germany in 

1966, Bio-Rad has continued to 

establish operations around the 

globe to ensure that we are not 

only able to provide our customers 

with the products they need, but 

also offer them optimum conve-

nience, value, and customer care. 

Our product training sites, situated 

around the world, offer post-sale  

technical support to ensure cus-

tomers are able to successfully 

use their products in their labs. 

24 hours after inoculation posed a 

logistical challenge for microbiology 

labs. Would it be possible to offer 

more flexibility by providing a range 

of time in which the test results 

could be read? We conducted 

Providing this level of customer 

additional studies and were able 

care throughout the sales cycle 

to broaden that time to between 

continues to produce relationships 

18 and 28 hours. This extended 

that have, in some cases, spanned 

timeframe resulted in not only 

three decades or more … and 

enhanced flexibility for diagnosti-

counting. It’s because we’re not 

cians, but even better, more rapid 

satisfied until we have exceeded 

identification of MRSA carriers so 

our customers’ expectations, and 

that hospitals could more quickly 

this personal involvement to us is 

implement appropriate infection 

business as usual.  

control as well as treatment.

page : 7

For example, our life science  

protein interaction user group played 

an integral role in the development 

of our ProteOn™ XPR36 protein 

interaction array system. In addition 

to participating in the testing of early 

prototypes, many of these users 

were involved in determining the 

product’s final specifications, and 

they participated in the product’s 

validation as well.

Bio-Rad Laboratories  |  Annual Report 2008  Business as Usual.

we stArt with whAt 
is the Best. And then 
figure out wAys to 
mAke it Better.

innovAtion tAkes mAny forms 

At Bio-rAd. whether it’s invent-

ing A new wAy to perform A 

common process, discovering 

new AnAlytics for cellulAr 

reseArch, or simply improving 

the wAy An instrument works, 

we Are AlwAys looking to rAise 

the BAr for whAt success 

should look like.

8 : page

pushing boundaries,
  Business as Usual.

Bio-Rad Laboratories  |  Annual Report 200810 : page

PuShi ng bou nda ri eS aS uSuaL

From product improvements and introducing next-generation 
technologies to looking far into the future to imagine even 
better solutions, Bio-Rad Research and Development  
is about helping our customers achieve their goals.  
Their success is our success.
Bio-Rad’s R&D teams are focused on delivering the highest-quality, most efficient, 
and yet affordable products and processes in the industry. That means provid-
ing better testing methods for our clinical diagnostics customers, and making 
innovative technologies for our life sciences customers. The result is a set of 
powerful tools that may lead to new discoveries and improved healthcare.

A good example of how this all 

Another way Bio-Rad serves its 

In addition to understanding 

comes together is the recent 

customers is by helping labora-

our customers’ needs of today, 

development of our in2it™ point- 

tories offer more value to their 

through careful observation of 

of-care analyzer, a diabetes 

customers. Because autoim-

market trends we look ahead 

testing platform that delivers 

mune diseases affect multiple 

and envision what those cus-

a patient’s A1C results from a 

body systems and often produce 

tomers might need in three to 

simple finger prick sample within 

ambiguous symptoms, identify-

five years’ time. Even farther out, 

minutes in a physician’s office. 

ing the disease is challenging. 

we look to the future and explore 

A1C is a protein found in the 

To assist in diagnosis, Bio-Rad 

a variety of ongoing technology 

blood that provides insight into 

developed its Medical Decision 

advancements, including those 

the average blood sugar levels in 

Support Software. With the help 

in the fields of cellular analysis 

diabetics over a several-month 

of pattern-recognition algorithms 

and process miniaturization.

period, and therefore helps a 

to aid in disease characterization, 

patient monitor and control this 

the software offers another level of 

disease. Additional customer 

analysis of test results suggesting 

feedback of the in2it system led 

a diagnosis of both common and 

to a number of improvements 

uncommon autoimmune diseases. 

that save time and reduce errors. 

This results in faster diagnosis and 

In addition to the convenience 

earlier treatment. 

In all cases, Bio-Rad’s empha-

sis on R&D is marked by the 

constant encouragement of 

our employees to do creative 

work—as evidenced by the more 

than doubling of the number of 

patents we have been awarded 

and timeliness of delivering 

results in a matter of minutes, 

studies have shown that when 

a patient and physician discuss 

test results face-to-face, this 

leads a greater exchange of 

information as well as feedback, 

ultimately leading to improved 

patient care.

In our Life Science Group, we 

over the past several years. 

continue to introduce new prod-

This investment back into our 

ucts as well as improve current 

business not only helps us push 

ones with new and innovative 

boundaries, it ensures the very 

technologies used to “separate, 

future of our company.

purify, analyze, and identify” 

biological and chemical materi-

als. Our next-generation precast 

gels improve the electrophoresis 

technology that we ourselves 

developed over 30 years ago.

page : 11

Bio-Rad Laboratories  |  Annual Report 2008  Business as Usual.

Bio-rAd Builds  
instruments—And 
confidence—thAt 
stAnd the test  
of time.

it’s not unusuAl to see severAl 

generAtions of Bio-rAd prod-

ucts on the Bench.  whether  

it’s our Biologic duoflow™ 

chromAtogrAphy systems or 

our lAtest AutomAted profiniA™ 

protein purificAtion system, 

reseArchers know they cAn 

depend on our products, from 

stArt to finish.

Tried a n d tru e,

  Business as Usual.

Bio-Rad Laboratories  |  Annual Report 200814 : page

tri ed  and tr ue aS uSuaL

Science, it is said, is the expression of what can be 
shown to work reliably and repeatedly. The same is true  
of Bio-Rad products and technologies.
The things we take for granted in today’s complex, modern life are a testament 
to how much we’ve come to rely on them. Whether it’s cell phones, computers,  
TVs, or cars, our relationships to these products are built on a single, underlying 
premise: that they work the way they’re supposed to. Plain and simple. When 
they don’t, they lose our trust. 

At Bio-Rad, this sense of reas-

Take our leadership in the field 

that offers automation, expanded  

surance is exactly what we build 

of diabetes testing, for example. 

volumes, and improved through-

into every one of our products 

From our first manual, open-

put—all of which help researchers 

and services, so scientists and 

column chromatography test 

more quickly and directly achieve 

healthcare professionals can 

introduced in 1978 and later the 

their goals. Today, our new Profinia™ 

focus on their work—and not 

VARIANT™ integrated, high-

line takes that notion a step further, 

whether or not their instruments 

performance liquid chromatog-

by being “pre-tuned” for specific  

are working properly.

raphy (HPLC) system to our fully 

applications, saving researchers 

automated VARIANT™ II TURBO 

even more effort and time.

Some of our product lines that 

were introduced decades ago 

still represent the state-of-the-art 

today because, over the years, 

we’ve continued to enhance 

their capabilities and applied 

and D-10™ systems today, 

our products have continually 

improved performance, thereby 

helping clinicians do their work 

more effectively and efficiently. 

Such a total approach to ensur-

ing the peace of mind of our 

customers also benefits us as a 

company because we are able to 

develop long-term relationships 

innovative ways to improve their 

Our Life Science Group has seen  

with our customers based on 

functionality and value. It’s an 

a similar evolution in chromatog-

their confidence that Bio-Rad  

approach that pays enormous 

raphy technology for proteomics 

always stands behind them. These 

dividends for our customers, 

research. In many separation 

relationships not only generate 

who know that they can have 

applications, where not only 

consistent revenue streams, but 

confidence in the results of any 

analytics but sample quantity is 

also enhance Bio-Rad’s half-

Bio-Rad product, whether it’s a 

important, our BioLogic DuoFlow™ 

century reputation as a strong, 

clinician looking at the outcome 

line of chromatography systems 

solid company—“tried and true”—

of a test or a researcher examin-

have increasingly become more 

positioning us well, for the future.

ing the results of an experiment.

powerful and easier to use. This 

has been achieved by building on 

our expertise in chromatography 

page : 15

Bio-Rad Laboratories  |  Annual Report 2008the right externAl 
opportunities cAn 
leAd to sustAined 
internAl growth.

from A diABetes monitoring 

technology in scotlAnd And 

quAlity controls in cAliforniA 

to the leAder in Blood typing 

in switzerlAnd, Bio-rAd Builds 

into our strAtegy An ongoing 

seArch for outside Businesses 

thAt complement our core 

strengths. the result? even 

greAter promise for our  

customers.

  Business as Usual.

ly    
C o n t i n u a l
               e v o l v i n g ,
  Business as Usual.

Bio-Rad Laboratories  |  Annual Report 200818 : page

con t i nuaLLy  evoL ving aS u SuaL

Most companies evolve through a balance of organic 
growth and acquisitions. Bio-Rad has been particularly  
adept in finding and integrating complementary businesses 
that add to our strengths.
Continuous improvement is a hallmark of successful companies the world 
over. Such organizations incorporate an ongoing, passion for positive,  
incremental change into every aspect of their operations. In our case, that 
means seeking to leverage our core competencies with organic growth as 
well as identifying external opportunities, all of which contribute to continually 
broadening our total product offerings and, in many cases, offering a  
complete solution for our customers’ needs.

Over the years, we’ve been 

Following our recent acquisition 

offerings will be complementary 

extremely sensitive to the needs 

of DiaMed, a developer, manufac-

to ours by broadening our prod-

of our customers in deciding 

turer, and marketer of a complete 

uct line and expanding our reach 

whether to develop a new prod-

line of reagents and instruments 

into new and existing markets 

uct or integrate a new technology 

used in blood typing and screen-

and geographies. 

or product line into our offerings. 

ing, we applied our own expertise 

At the same time, we ensure 

to begin developing a new, fully 

that the acquisitions we seek 

automated instrument for blood 

are those that will expand our 

typing. DiaMed’s safe, easy-to-use, 

existing product portfolio, taking 

and reliable products are already 

newly acquired products into new 

responsible for over hundreds 

geographic markets, and leverag-

of millions of blood typing tests 

ing our distribution strength to 

performed each year around the 

improve the success of an ac-

world, and the company’s integra-

quired company or technology.   

tion into Bio-Rad will allow us to 

The result has been a strong 

track record of integrating 

expand the benefits of greater lab 

efficiency into new markets.

complementary businesses that 

While such acquisitions represent 

have proven to be of tremendous 

fairly large, complex integrations, 

benefit to our clinical diagnostics 

we also look for opportunities 

and life science customers, as 

with companies that have specific 

well as to the company itself.

technologies when we feel their 

Our attitude of continually looking 

for ways to improve our products 

and services extends inward as 

well. From the integration of in-

novative upgrades to our informa-

tion technology to the application 

of more cost effective methods 

of manufacturing operations, we 

are constantly looking for ways to 

do things better. As an evolution-

ary process, it is, one might say, 

simply in our nature.

page : 19

Bio-Rad Laboratories  |  Annual Report 2008  Business as Usual.

introducing  
the scientists  
of tomorrow.

from middle school And  

college-level science projects 

to high school scholArships 

And science fAirs, Bio-rAd  

extends its reAch to inspire the 

next generAtion of scientists. 

And why shouldn’t they? our 

future is in the hAnds of our 

youth, And we owe them nothing 

less thAn the Best tools possiBle.

I n s p i ri n g    
            y o u n g   m i n d s,
  Business as Usual.

Bio-Rad Laboratories  |  Annual Report 200822 : page

inS Pir i ng  Mi ndS aS uSuaL

The foundation of an informed society is the literacy  
of its citizens. Bio-Rad’s outreach efforts focus on  
exposing today’s students to the wonders of science  
in a fun, hands-on way.
Kids are impressionable. When things are made fun and interesting for them, 
the greater the chance that they will become interested, which is precisely 
the idea behind our efforts to foster science education and inspire the  
budding young scientists of tomorrow.

The centerpiece of this effort is our 

This year, we launched the indus-

approach, the program has proved 

Biotechnology Explorer™ program 

try’s first multi-topic curriculum on 

enormously successful in its initial 

that began in the late 1990s with 

cloning and sequencing in molecu-

rollout, being implemented at more 

a curriculum designed for high 

lar biology for entry-level college 

than triple the number of institu-

school-level students. It was a time 

students. This eight-module series 

tions than originally anticipated. 

when science teachers around the 

teaches students how to isolate 

world were discovering that their 

plant DNA—whether from Arizona 

existing curricula were not keeping 

desert plants, a backyard daisy, or 

up, as a number of scientific top-

a piece of cabbage in the refrig-

ics began cropping up in popular 

erator—and then amplify critical 

culture stirring the curiosities of 

genes, engineer them into bacteria, 

students with terms such as hu-

and then sequence the genes. 

man genome, DNA, and cloning. 

Students can then publish their 

Bio-Rad worked closely with 

results in “GenBank®,” the National 

educators to develop a program 

Center for Biotechnology Informa-

that provided instructors lesson 

tion’s database, which houses a 

materials that corresponded with 

collection of publicly available  

Bio-Rad equipment. Students 

DNA sequences.   

Bio-Rad has continued to seek 

other avenues to reach out to even 

younger potential future scientists, 

which is often when an individual 

first discovers they have an interest 

in the sciences. Bio-Rad spon-

sors a variety of activities such 

as science summer camp and 

science fairs and competitions, 

where we provide both equipment 

and judges—Bio-Rad employees, 

who seem to get as much out 

of the interaction with the bright 

were engrossed when working 

with real-life instruments that were 

actually used in today’s labs. They 

could see how easy it was to cap-

ture (and see) their own DNA and 

genetically engineer bacteria—

themselves. Since the program 

was first launched, it has reached 

hundreds of thousands students in 

educational institutions worldwide. 

The new college-level Biotech-

young students as do the students 

nology Explorer series provides 

themselves. How inspiring!

instructors the tools they need to 

teach the entire six- to eight-week 

course, giving students a full grasp 

of the principles of biotechnol-

ogy and molecular biology. As 

a result of this comprehensive 

page : 23

Bio-Rad Laboratories  |  Annual Report 2008  Business as Usual.

welcome to A  
mutuAl Benefit  
society like  
no other.

when you tAlk ABout return 

on An investment, At Bio-rAd we 

like to think thAt there is none 

higher thAn the return we  

receive from our employees. we 

Are diligent in our Attention to 

them, And yet their dedicAtion, 

outlook, And work product 

continuAlly surpAsses our 

greAtest expectAtions. when 

this rel Ationship works,   

every thing works.

I n v e st i n g  
                        i n   u s
  Business as Usual.

Bio-Rad Laboratories  |  Annual Report 200826 : page

inveSti ng i n uS aS uSuaL

Our people are key to our success. We provide them with 
the opportunity to develop new ideas and the freedom 
to explore different avenues in pursuit of their goals.
Since we first began, Bio-Rad has cultivated an entrepreneurial spirit,  
encouraging the free flow of ideas, creativity, and independence at every 
level of our organization. Employees are encouraged to fulfill their professional 
aspirations within the company, which sometimes means switching gears 
mid-career to head in an another direction. 

It’s not uncommon, for example, 

But a strong support team was 

advancing scientific discovery;  

to find someone who began 

there for her, and she was thrilled 

I just couldn’t ask for a better 

at Bio-Rad in one area only to 

to have the chance to learn on the 

company to work for.” 

discover an interest in another 

job, an opportunity she describes 

facet of our operation. Take Diane, 

as simply “incredible.” 

When one joins Bio-Rad, he or 

she will quickly discover that the 

After a couple of years, she tran-

burned the midnight oil learning 

sitioned to a position as marketing 

and just taking it all in. 

who’s been with Bio-Rad for over 

20 years. She had been working  

in a hospital laboratory when the 

Bio-Rad sales representative 

walked in. She listened to him sell 

a Bio-Rad product to her manager 

and thought, I can do that! She 

pursued a sales career at Bio-Rad 

and soon landed a position as 

sales representative. 

product manager, then became 

a regional sales manager. A few 

years down the line she became a 

national sales manager, then later 

a division manager. Eventually  

she was asked to manage one of 

Bio-Rad’s manufacturing divisions—

a huge leap for her—she says, 

since her background was in sales 

and marketing and not operations.  

She recalls learning—from the 

only limits that may stand in the 

ground up—about many new 

way are those he or she places on 

functions: regulatory, quality assur-

themselves. To us, the sky’s the 

ance, quality control, manufactur-

limit. All one needs is the desire 

ing, R&D, and finance. “I pulled my 

and willingness to do what it takes 

finance manager aside and said, 

to make it happen.  

‘teach me everything you know 

about cost accounting,’” she says. 

She rolled up her sleeves and dove 

into the details. Some nights she 

Investing in our employees is one of 

the cornerstones of our company 

because we know that not only 

do personal satisfaction and new 

ideas fuel growth, they also fuel a 

powerful sense of involvement on 

The long hours paid off. Today she 

the part of individuals and teams.

heads a number of divisions and 

says the people she works with 

at Bio-Rad never cease to amaze 

her with their level of commitment, 

dedication, and creativity. While 

she loves what she does, it’s also 

the field that she’s in that she finds 

so fulfilling. “It’s great to know that 

we are helping change people’s 

lives with better healthcare and  

All of this adds up to being a 

place where people can feel  

the greatest sense of personal 

satisfaction knowing that,  

together and as individuals,  

we are making a difference.  

And we couldn’t ask for a much 

better return on our investment.

page : 27

Bio-Rad Laboratories  |  Annual Report 2008Bio-Rad Laboratories  |  Annual Report 2008

the buSineS S of bi o-ra d

Bio-Rad Laboratories has played a leading role in the 
advance ment of scientific discovery for over 50 years by 
providing a broad range of innovative tools and services to 
the life science research and clinical diagnostics markets.

Founded in 1952, Bio-Rad has a global team of more than 6,500 employees and 
serves more than 85,000 research and industry customers worldwide through its 
global network of operations. Throughout its existence, Bio-Rad has built strong  
customer relationships that advance scientific research and development efforts and 
support the introduction of new technology used in the growing fields of genomics, 
proteomics, drug discovery, food safety, medical diagnostics, and more.

L i f e   S c i e n c eS

c Li n i c aL di a g n oSt i cS

Bio-Rad’s Life Science Group 

Clinical Diagnostics develops,  

develops, manu factures, and 

manufactures, sells, and 

markets a wide range of labora-

supports a large portfolio of 

tory instruments, apparatus, and 

products for medical screening 

consumables used for research in 

and diagnostics. Bio-Rad is the 

functional genomics, pro teomics, 

leading specialty diagnostics 

and food safety. The group ranks 

company in the world and its 

among the top five life science 

products are recognized as 

companies world wide, and main-

the gold standard for diabetes 

tains a solid reputation for quality, 

monitoring and quality control 

innovation, and commitment to its 

(QC) systems. The company is 

customers. Bio-Rad’s life science 

also well known for its blood 

products are based on technolo-

virus testing and detection, 

gies used to separate, purify, iden-

blood typing, autoimmune and 

tify, analyze, and amplify biological 

genetic disorders testing, and 

materials such as proteins and 

internet-based soft ware products. 

nucleic acids. These technologies 

Bio-Rad’s clinical diagnostics 

include electrophoresis, imaging, 

products incorporate a broad 

multiplex immunoassay, chroma-

range of technolo gies used to 

tography, microbiology, bioinfor-

detect, identify, and quantify 

matics, protein function analysis, 

sub stances in bodily fluids and 

transfection, amplification, and 

tissues. The results are used as 

real-time PCR. Bio-Rad products 

aids to support medical diagno-

support researchers in laborato-

sis, detection, evaluation, and 

ries throughout the world.

the monitoring and treatment 

of diseases and other medical 

28 : page

2008 FINANCI AL HIGHLIGHTS

fi v e -ye ar  reCorD

( i n   m i l l i o nS,   e xCePt  Pe r  Sh a r e  Data )

Net Sales 

Gross Profit 

Research Expenditures 

Net Income 

Return On Sales 

2004 

2005 

2006 

2007  

2008 

$ 1,090.0 

$ 1,181.0 

$ 1,273.9 

$ 1,461.1 

$ 1,764.4

$  610.1 
$  108.31 
68.2 
$ 

$  646.5 

$  115.1 

$ 

81.6 

$  712.5 
$  123.41 
$  103.3 

$  791.4 
$  140.51 
93.0 
$ 

$  962.5

$  159.5

$ 

89.5

  6.3% 

 6.9% 

   8.1% 

   6.4% 

  5.1%

Book Value Per Share 

$  23.10 

$  25.09 

$  30.92 

$  36.14 

$  38.09

Basic Earnings Per Share 

$ 

2.65 

$ 

3.13 

$ 

3.92 

$ 

3.49 

$ 

3.32

Cash Flow From Operations 

$  123.1 

$  108.3 

$  118.2 

$  191.6 

$  191.4

1. exCluDeS $14.6, $4.1 anD $7.7 of PurChaSeD r&D in 2004, 2006 anD 2007, reSPeCtively

2008 SaleS By region

net SaleS
    ( i n   m i l l i o nS)

CaSh flow   
from oPerationS
    ( i n   m i l l i o nS)

BaSiC earningS  
Pe r S hare

4
.
4
6
7
1
1 $
.
1
6
4
1
$

9
.
3
7
2
1
$

0
.
1
8
1
1
$

0
.
0
9
0
1
$

6
.
1
9
1
$

4
.
1
9
1
$

1
.
3
2
1
$

2
.
8
1
1
$

3
.
8
0
1
$

2
9
.
3
$

9
4
.
3
$

2
3
.
3
$

3
1
.
3
5 $
6
.
2
$

49%
Europe

15%
Pacific
  Rim

36%
Americas

04  05  06  07  08

04  05  06  07  08

04  05  06  07  08

StoCK Pe r for manCe gr aPh

The following graph compares the cumulative stockholder returns over the past five years for the Company’s Class A Common Stock, 
the American Stock Exchange Value Index, the S&P 400 MidCap Index, and a selected peer group, assuming $100 invested on 
December 31, 2003, and reinvestment of dividends if paid:

S
R
A
L
L
O
D

250

200

150

100

50

0

Bio-Rad

Peer Group 1

AMEX Market 
Value Index

S&P MidCap 400 2

2003 

2004 

2005 

2006 

2007 

2008

1. The Peer Group consists of the following public companies: Beckman Coulter, Becton Dickinson, Thermo Fisher Scientific, Meridian Bioscience, Millipore, PerkinElmer 
and Life Technologies. This group differs from prior years as two of our former peers, Applera Corp. and Invitrogen, merged to form Life Technologies. Companies in our 
peer group reflect our participation in two different markets: life science research products and clinical diagnostics. No single public or private company has a comparable 
mix of products which serve the same markets. In many cases, only one division of a peer group company competes in the same market as we do. Collectively, however,  
our peer group reflects products and markets similar to those of Bio-Rad.

2. Note that this year the Company has selected the S&P 400 MidCap Index as its new comparable index as the Company’s stock moved to the New York Stock Exchange 
in October 2008. The Company’s stock is one element of this index.
This stock performance graph shall not be deemed incorporated by reference by any general statement incorporating by reference into any filing under the 
Securities Act or the Exchange Act, and shall not otherwise be deemed filed under these Acts.

page : 29

Competitor

S&P

Year

Average

Bio-Rad AMEX

Midcap 400

2003

2004

2005

2006

100

130

153

174

100

99

113

143

100

122

150

175

100

115

128

140

Bio-Rad Laboratories  |  Annual Report 2008 
 
 
 
 
 
 
SA LES HISTORY

Bio-rAd lABorAtories 

plAys A leAding role 

in the AdvAncement of 

scientific discovery 

By providing A BroAd rAnge of 

innovAtive tools And services to 

the life science reseArch And 

clinicAl diAgnostics industries. 

the compAny is world renowned 

Among hospitAls, universities, 

mAjor reseArch institutions, 

Biotechnology compAnies And 

1970

1959

1965

phArmAceuticAl firms for its 

commitment to quAlity And cus-

tomer service. 

30 : page

$1.7 billion

$1.6 billion

$1.5 billion

$1.4 billion

$1.3 billion

$1.2 billion

$1.1 billion

$1 billion

$900 million

$800 million

$700 million

$600 million

$500 million

$400 million

$300 million

$200 million

$100 million

1975

1980

1985

1990

1995

2000

2008

SummARy of opeRA tionS And SeLected finAnciAL dA tA

(in thousands, except per share data) 

2008 

2007 (2)   

2006  

2005  

2004

Year Ended December 31, 

Net sales 

$ 1,764,365   $ 1,461,052   $ 1,273,930   $ 1,180,985   $  1,090,012

  Cost of goods sold 

  801,843  

  669,690  

  561,394  

  534,499  

  479,939

Gross profit 

  962,522  

  791,362  

  712,536  

  646,486  

  610,073

  Selling, general and administrative expense    591,304  

  507,978  

  438,949  

  416,084  

  378,264

  Product research and development expense    159,518  

  140,535  

  123,376  

  115,104  

  108,344 

  Purchased in-process research and  

  development expense 

—  

7,656  

4,100  

—  

14,620

Impairment losses on goodwill and  

long-lived assets 

Interest expense 

  Foreign exchange (gains) losses  

28,757  

32,113  

7,634  

—  

31,606  

2,576  

—  

32,022   

1,053  

19,770  

32,643  

(1,528) 

— 

20,219 

2,394  

  Other (income) expense, net (1) 

353  

(19,832) 

(28,991) 

(28,958) 

(11,095)

Income from continuing operations before  

taxes and minority interests 

  142,843  

  120,843  

  142,027  

  Provision for income taxes 

(44,579) 

(26,548) 

(38,764) 

93,371  

(15,792) 

97,327

(31,035)

  Minority interests in earnings of  

  consolidated subsidiaries 

(8,754) 

(1,301) 

—  

—  

— 

Income from continuing operations 

89,510  

92,994  

  103,263  

77,579  

66,292

Discontinued operations

  Loss from discontinued operations (net of tax) 

  Gain on divestiture (net of tax) 

Total income from discontinued operations 

—  

—  

—  

—  

—  

—  

—  

—  

—  

—  

3,974  

3,974  

(1,487)

3,437

1,950

Net income 

$ 

89,510   $ 

92,994   $  103,263   $ 

81,553   $ 

68,242

Basic earnings per share:

  Continuing operations  

  Discontinued operations 

  Basic earnings per share  

Diluted earnings per share:

  Continuing operations  

  Discontinued operations 

$ 

$ 

$ 

3.32   $ 

3.49   $ 

3.92   $ 

2.98   $ 

—  

—  

—  

0.15  

3.32   $ 

3.49   $ 

3.92   $ 

3.13   $ 

3.25   $ 

3.41   $ 

3.83   $ 

2.91   $ 

 —

—  

—  

0.15  

  Diluted earnings per share  

$ 

3.25   $ 

3.41   $ 

3.83   $ 

3.06   $ 

Cash dividends paid per common share 

—  

—  

—  

—  

2.58

0.07

2.65

2.51 

0.07

2.58

—  

Total assets 

$ 2,037,264   $ 1,971,594   $ 1,596,168   $ 1,426,582   $  1,371,618

Long-term debt, net of current maturities 

$  445,979   $  441,805   $  425,625   $  425,687   $  425,979

(1) See Note 10 to the consolidated financial statements for components of Other income, net. Included in 2005 is interest and investment income of  

$16.7 million, gains on sales of investments of $11.2 million and litigation expense of $1.2 million. Included in 2006 is interest and investment income 
of $22.2 million and gains on sales of investments of $4.7 million. Included in 2007 is interest and investment income of $21.5 million offset by a $3.6 
million write-down of investments. Included in 2008 is interest and investment income of $10.6 million offset by a $9.6 million other-than-temporary 
impairment on investments.

(2) Included in 2007 are the fourth quarter operating results of an acquisition. See Note 2 to the consolidated financial statements.

Bio-Rad Laboratories  |  Annual Report 2008  :  31 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
conSoLidA ted BALAnce SheetS 

(in thousands) 

AS SETS 

Current assets: 

  Cash and cash equivalents 

  Short-term investments 

December 31,

2008  

2007

$  204,524  

$  161,764

38,950  

61,977

  Accounts receivable less allowance of $19,567 in 2008 and $21,410 in 2007 

  339,653  

  358,076

Inventories, net: 

  Raw materials 

  Work in process 

  Finished goods 

  Total inventories 

  Deferred tax assets 

  Prepaid expenses and other current assets 

  Total current assets 

Property, plant and equipment: 

  Land and improvements 

  Buildings and leasehold improvements 

  Equipment 

  Total property, plant and equipment 

  Accumulated depreciation 

  Property, plant and equipment, net 

Goodwill 

Purchased intangibles, net 

Long-term deferred tax assets 

Other assets 

69,549  

  105,007  

61,555

88,375

  201,060  

  171,085

  375,616  

  321,015

41,408  

36,450

93,790  

89,692

 1,093,941  

 1,028,974 

16,567  

11,929

  193,318  

  181,772

  466,024  

  420,628

  675,909  

  614,329

  (375,177) 

  (342,768)

  300,732  

  271,561

  321,820  

  328,439

  228,590  

  210,304

12,361  

20,429

79,820  

  111,887

TO TAL  ASSET S 

$ 2,037,264  

$ 1,971,594 

The accompanying notes are an integral part of these consolidated financial statements. 

32  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(in thousands, except share data) 

LIABILITIES AND STOCKHOLDERS’ EQ UITY 

Current liabilities: 

  Accounts payable 

  Accrued payroll and employee benefits 

  Notes payable 

  Current maturities of long-term debt 

  Sales, income and other taxes payable 

  Accrued royalties 

  Current deferred taxes 

  Other current liabilities 

  Total current liabilities 

Long-term debt, net of current maturities 

Deferred tax liabilities 

Other long-term liabilities 

  Total liabilities 

Commitments and contingent liabilities 

Minority interests 

Stockholders’ equity:

  Preferred stock, $0.0001 par value, 7,500,000 shares authorized;

  none outstanding 

  Class A common stock, $0.0001 par value, 80,000,000 shares authorized;

  outstanding—22,182,451 at 2008 and 21,877,695 at 2007  

  Class B common stock, $0.0001 par value, 20,000,000 shares authorized; 

  outstanding—5,137,357 at 2008 and 5,006,440 at 2007  

  Additional paid-in capital 

  Retained earnings 

  Accumulated other comprehensive income: 

  Currency translation and other 

December 31,

2008 

2007

$  117,982 

$ 

96,470

  119,420 

  121,255

2,409 

7,169 

33,731 

30,874 

8,159 

4,630

10,997

27,905

44,069

2,134

98,290 

  106,708

  418,034 

  414,168

  445,979 

  441,805

42,570 

60,041 

51,215

58,282

  966,624 

  965,470

— 

—

29,909 

34,434

— 

2 

1 

—

2

1 

  124,401 

98,629

  851,577 

  762,067

64,750 

  110,991

  Total stockholders’ equity 

 1,040,731 

  971,690 

TO TAL LIABILITIES, MINORITY IN TERESTS A ND  

  STOCKHOLDERS’ E QUITY 

$ 2,037,264 

$ 1,971,594 

The accompanying notes are an integral part of these consolidated financial statements.

Bio-Rad Laboratories  |  Annual Report 2008  :  33 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
conSoLidA ted StAtementS of income

(in thousands, except per share data) 

Net sales 

  Cost of goods sold 

Gross profit 

  Selling, general and administrative expense 

  Product research and development expense 

  Purchased in-process research and development expense 

Impairment losses on goodwill and long-lived assets 

Income from operations 

Interest expense 

  Foreign exchange losses 

  Other (income) expense, net 

Income before taxes and minority interests 

  Provision for income taxes 

  Minority interests in earnings of consolidated subsidiaries 

Net income 

Basic earnings per share: 

  Net income 

  Weighted average common shares 

Diluted earnings per share: 

  Net income 

  Weighted average common shares 

The accompanying notes are an integral part of these consolidated financial statements.

 Year Ended December 31,

2008  

2007  

2006

$ 1,764,365  

$ 1,461,052  

$ 1,273,930 

  801,843  

  669,690  

  561,394

  962,522  

  791,362  

  712,536

  591,304  

  507,978  

  438,949

  159,518  

  140,535  

  123,376

—  

28,757  

7,656  

—  

4,100

—

  182,943  

  135,193  

  146,111

32,113  

7,634  

353  

31,606  

2,576  

(19,832) 

32,022

1,053

(28,991)

  142,843  

  120,843  

  142,027

(44,579) 

(8,754) 

(26,548) 

(1,301) 

(38,764)

—

$ 

89,510  

$ 

92,994  

$  103,263

$ 

3.32  

$ 

3.49  

$ 

3.92

27,001  

26,684  

26,376

$ 

3.25  

$ 

3.41  

$ 

3.83

27,527  

27,260  

26,949

34  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
conSoLidAted StAtementS of cASh fLowS 

(in thousands) 

Cash flows from operating activities: 

  Cash received from customers 

  Cash paid to suppliers and employees 

  Litigation settlement (See Note 13) 

Interest paid 

Income tax payments 

  Miscellaneous receipts  

  Excess tax benefits from share-based compensation 

 Year Ended December 31,

2008  

2007  

2006

$ 1,765,667  

$ 1,467,626  

$ 1,247,779

 (1,495,669) 

 (1,225,968) 

 (1,058,977)

(4,493) 

(30,792) 

(49,159) 

(4,228) 

(30,588) 

(38,253) 

10,867  

  25,983  

(5,050) 

(2,992) 

(46,981)

(31,049)

(16,072)

24,914 

(1,385)

  Net cash provided by operating activities 

  191,371  

  191,580  

  118,229

Cash flows from investing activities: 

  Capital expenditures, net 

  Payments for acquisitions, net of cash received, 

   and long-term investments 

  Proceeds from divestitures 

  Payments for purchase of intangible assets 

(84,809) 

(60,595) 

(52,987)

(53,014) 

  (387,673) 

—  

—  

(4,000) 

(2,075) 

(46,071)

12,772

—

  Purchases of marketable securities and investments 

(77,800) 

  (270,174) 

  (334,047)

  Sales of marketable securities and investments 

  Foreign currency economic hedges, net 

  Receipt of restricted cash 

  Net cash used in investing activities 

78,906  

  470,200  

  178,643

(5,390) 

(4,112) 

—  

—  

(2,196)

36,138

  (146,107) 

  (254,429) 

  (207,748)

Cash flows from financing activities:   

  Net payments on notes payable 

  Long-term borrowings 

  Payments on long-term debt 

  Proceeds from issuance of common stock 

  Excess tax benefits from share-based compensation 

  Net cash provided by (used in) financing activities 

(1,642) 

1,600  

(4,326) 

24  

(11,589) 

(17,720) 

12,912  

  11,580  

5,050  

6,331  

2,992  

(7,450) 

(659)

—

(487)

9,923

1,385

10,162

Effect of exchange rate changes on cash 

(8,835) 

8,456  

6,248

Net increase (decrease) in cash and cash equivalents 

42,760  

(61,843) 

(73,109)

Cash and cash equivalents at beginning of year 

Cash and cash equivalents at end of year 

  161,764  

  223,607  

  296,716

$  204,524  

$  161,764  

$  223,607

Non-cash investing activities:

  Tender of Accent stock 

  Receipt of Nanometrics stock 

  Capital lease obligation for facilities 

  Purchased intangible assets 

The accompanying notes are an integral part of these consolidated financial statements.

$ 

$ 

$ 

$ 

—  

—  

9,768  

11,357  

$ 

$ 

$ 

$ 

—  

—  

—  

—  

$ 

$ 

$ 

$ 

(3,200)

5,354

—

—

Bio-Rad Laboratories  |  Annual Report 2008  :  35 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
conSoLidA ted StAtementS of chAngeS in StockhoLdeRS’ equity

(in thousands) 

Common stock, $0.0001 par value:

  Balance at beginning of year 

Issuance of common stock 

  Balance at end of year 

Additional paid-in capital:

  Balance at beginning of year 

Issuance of common stock 

  Stock compensation expense 

  Tax benefit from exercise of stock options 

  Balance at end of year 

Retained earnings:

  Balance at beginning of year 

  Net income 

  FIN 48 adjustment 

  Balance at end of year 

Accumulated other comprehensive income:

  Balance at beginning of year 

  Other comprehensive income (loss)  

  Balance at end of year 

 Year Ended December 31,

2008  

2007  

2006

$ 

3  

$ 

3  

$ 

—  

3  

—  

3  

3

—

3

98,629  

12,912  

7,328  

5,532  

78,230  

11,580  

5,506  

3,313  

60,112

9,923

5,363

2,832

  124,401  

98,629  

78,230

  762,067  

  674,070  

  570,807 

89,510  

92,994  

  103,263 

—  

(4,997) 

—

  851,577  

  762,067  

  674,070

  110,991  

(46,241) 

67,235  

43,756  

64,750  

  110,991  

27,052

40,183

67,235

Total stockholders’ equity 

$ 1,040,731  

$  971,690  

$  819,538

Comprehensive income, net of tax:

  Net income 

  Currency translation adjustments 

$ 

89,510  

$ 

92,994  

$  103,263

(18,671) 

45,856  

30,059

  Other post-employment benefits adjustments net of tax of

($357) in 2008 

1,848  

—  

—

  Net unrealized holding gains (losses) net of tax of ($9,381)

in 2008, ($1,396) in 2007, and $5,767 in 2006 

(19,162) 

(2,433) 

10,175

  Reclassification adjustments for gains (losses) included in net income,

  net of tax of $0 in 2008, ($193) in 2007, and $30 in 2006  

(10,256) 

333  

(51)

Total comprehensive income, net of tax 

$ 

43,269  

$  136,750  

$  143,446 

The accompanying notes are an integral part of these consolidated financial statements.

36  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS

1. SIGNIFICANT ACCOUNTING POLICIES

Basis of Presentation

The consolidated financial statements include the accounts of Bio-Rad Laboratories, Inc. and all subsidiaries 

(referred to in this report as “Bio-Rad,” “we,” “us” and “our”) after elimination of intercompany balances and 

transactions. The preparation of financial statements in conformity with accounting principles generally accepted 

in the United States of America requires management to make estimates and assumptions that affect the amounts 

reported in the financial statements and accompanying notes. Actual results could differ from those estimates. 

Cash and Cash Equivalents

Cash and cash equivalents consist of cash and highly liquid investments with original maturities of three months or 

less which are readily convertible into cash. Cash equivalents are stated at cost, which approximates fair market value.

Available-for-Sale Investments

Available-for-sale investments consist of corporate obligations, municipal securities, asset backed securities, 

U.S. agencies and marketable equity securities. Management classifies investments at the time of purchase and 

reevaluates such classification at each balance sheet date. Investments with maturities beyond one year may 

be classified as short-term based on their liquid nature and because such marketable securities represent the 

investment of cash that is available for current operations. Available-for-sale investments are reported at fair value 

based on quoted market prices and other observable market data. Unrealized gains and losses are reported as a 

component of other comprehensive income, net of any related tax effect. Unrealized losses are charged against 

income when a decline in the fair market value of an individual security is determined to be other than temporary. 

We review our available-for-sale investments for other-than-temporary losses on a quarterly basis. Realized gains 

and losses and other than temporary impairments on investments are included in Other income, net (see Note 10).

Concentration of Credit Risk

Financial instruments that potentially subject us to concentration of credit risk consist primarily of cash and cash 

equivalents, short-term investments and trade accounts receivable. Cash and cash equivalents and short-term 

investments are placed with highly rated major financial institutions. We perform credit evaluation procedures 

related to our trade receivables and with the exception of certain developing countries, generally do not require 

collateral. As a result of increased risk in these developing countries, some Bio-Rad sales are subject to collateral 

letters of credit. Credit risk is generally limited due to the large number of customers and their dispersion across 

many geographic areas. However, a significant amount of trade receivables are with national healthcare systems 

in countries within the European Economic Community. We do not currently anticipate a credit risk associated with 

these receivables.

Allowance for Doubtful Accounts

We maintain an allowance for doubtful accounts for estimated losses resulting from the inability of our customers  

to make required payments. The amount of the allowance is determined by analyzing known uncollectible accounts, 

aged receivables, economic conditions in the customers’ country or industry, historical losses and our customers’ 

credit-worthiness. Amounts later determined and specifically identified to be uncollectible are charged or written off 

against this reserve. This valuation allowance is reviewed quarterly to determine whether a change is warranted. 

Bio-Rad Laboratories  |  Annual Report 2008  :  37 

 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

Inventory Valuation

Inventories are valued at the lower of actual cost or market and include material, labor and overhead costs. 

Management reviews the need for an inventory obsolescence reserve on a quarterly basis or, if warranted by 

circumstances, more frequently. In evaluating this reserve, technology changes, competition, customer demand 

and manufacturing quality are considered.

Property, Plant and Equipment

Property, plant and equipment are carried at historical cost. Included in property, plant and equipment is reagent 

rental equipment. We provide these instruments to our customers for use with our reagents. Property, plant and 

equipment are assessed for impairment annually or whenever events or changes in circumstances indicate that 

the carrying amount may not be recoverable.

Depreciation is computed on a straight-line basis over the estimated useful lives of the assets. Buildings and 

leasehold improvements are amortized over 15-30 years or the lives of the leases or improvements, whichever  

is shorter. With the exception of reagent rental equipment, which is amortized over a 1-5 year period, equipment  

is depreciated over 3-12 years.

Capital expenditures are net of proceeds from the sale of property, plant and equipment of $0.9 million,  

$0.2 million and $0.3 million for 2008, 2007, and 2006, respectively.

Goodwill and Other Purchased Intangible Assets

Goodwill represents the excess of the cost over the fair value of net tangible and identifiable intangible assets of 

acquired businesses. Goodwill and intangible assets are assessed for impairment by applying fair-value based 

tests annually or whenever events or changes in circumstances indicate that the carrying amount may not be 

recoverable. Impairment expense is calculated as the excess of the carrying value of the asset over its fair value. 

The fair value is estimated based on its discounted future cash flows. Impairment losses of $28.8 million were 

recorded in 2008. No impairment was recorded for 2007 or 2006 (see Note 5).

Income Taxes

We account for income taxes under the asset and liability method, which requires the recognition of deferred  

tax assets and liabilities for the expected future tax consequences of events that have been included in the financial 

statements. Under this method, deferred tax assets and liabilities are determined based on the differences between 

the financial statements and tax basis of assets and liabilities using enacted tax rates in effect for the year in which 

the differences are expected to reverse. The effect of a change in tax rates on deferred tax assets and liabilities is 

recognized in income in the period that includes the enactment date.

We record net deferred tax assets to the extent we believe these assets will more likely than not be realized. In 

making such determination, we consider all available positive and negative evidence, including scheduled reversals 

of deferred tax liabilities, projected future taxable income, tax planning strategies and recent financial operations. 

To the extent we determine that we are able to realize our deferred income tax assets in the future in excess of 

their net recorded amount, we make an adjustment to the valuation allowance which may reduce the provision  

for income taxes.

38  :  Bio-Rad Laboratories  |  Annual Report 2008

Revenue Recognition

Revenue is recognized when pervasive evidence of an arrangement exists, the price to the buyer is fixed or deter-

minable, collectibility is reasonably assured and title has passed to the customer or product has been delivered 

absent specific contractual specifications. Equipment that requires factory installation is not recorded until installation 

is complete and customer acceptance, if required contractually, has occurred. At the time the related revenue is 

recognized, a provision is recognized for estimated product returns. Reagent agreements are a diagnostic industry 

sales method that provides use of an instrument if the customer exclusively purchases the company’s reagents 

to use on that instrument. We have evaluated the reagent agreements and account for the contracts under the 

terms of the guidance set forth in EITF 00-21, Accounting for Revenue Arrangements with Multiple Deliverables. 

All revenues that we earn under our reagent agreements are recognized when the reagent has been delivered to 

the customer. Service revenues on extended warranty contracts are recognized ratably over the life of the service 

agreement or as services are performed, if not under contract.

Shipping and Handling

We classify all freight billed to customers as net sales. Related freight costs are included in cost of goods sold. 

Warranty

We warrant certain equipment against defects in design, materials and workmanship, generally for a period of one 

year. Upon delivery of that equipment, we establish, as part of cost of goods sold, a provision for the expected 

costs of such warranty based on historical experience, specific warranty terms and customer feedback. A review  

is performed on a quarterly basis to assess the adequacy of our warranty reserve.

Components of the warranty accrual, included in Other current liabilities and Other long-term liabilities, were as 

follows (in millions):

January 1  

  Provision for warranty 

  Actual warranty costs 

  DiaMed acquisition 

December 31 

Research and Development

  2008  

  2007

$  15.3  

$ 

  18.5  

(18.0) 

  —  

12.9

14.9

(13.3)

0.8

$  15.8  

$ 

15.3

Internal research and development costs are expensed as incurred. Third-party research and development costs 

are expensed when the contracted work has been performed. Purchased in-process research and development 

costs are expensed at the time of purchase.

Foreign Currency 

Balance sheet accounts of international subsidiaries are translated at the current exchange rate as of the end of the 

accounting period. Income statement items are translated at average exchange rates for the period. The resulting 

translation adjustment is recorded as a separate component of stockholders’ equity.

Foreign currency transaction gains and losses are included in Foreign exchange (gains) losses in the Consolidated 

Statements of Income. Transaction gains and losses result primarily from fluctuations in exchange rates when 

intercompany receivables and payables are denominated in currencies other than the functional currency of our 

subsidiary that recorded the transaction.

Bio-Rad Laboratories  |  Annual Report 2008  :  39 

 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

Forward Exchange Contracts

As part of distributing our products, we regularly enter into intercompany transactions. We enter into forward foreign 

currency exchange contracts to manage foreign exchange risk of future movements in foreign exchange rates that affect 

foreign currency denominated intercompany receivables and payables. We do not use derivative financial instruments 

for speculative or trading purposes. In accordance with Statement of Financial Accounting Standards (SFAS) 133, 

Accounting for Derivative Instruments and Hedging Activities, we do not seek hedge accounting treatment for these 

contracts. As a result, these contracts, generally with maturity dates of 90 days or less and related primarily to 

currencies of industrial countries, are recorded at their fair value at each balance sheet date. The resulting gains  

or losses offset exchange gains or losses on the related receivables and payables, both of which are recorded as 

Foreign exchange (gains) losses in the Consolidated Statements of Income. The cash flows related to these 

contracts are classified as cash flows from investing activities in the Consolidated Statements of Cash Flows.

Minority Interests

We do not own 100% of the voting stock of some of our consolidated subsidiaries. The remaining shares held  

by third parties represent a minority (or noncontrolling) interest in these subsidiaries. Our consolidated statements 

present the full amount of assets, liabilities, income and expenses of all of our consolidated subsidiaries, with 

offsetting amounts shown in Minority Interests for the portion of these items that do not belong to us.

Employee Share-Based Compensation Plans

We maintain stock option and stock award plans for officers and certain other key employees. We also have an 

employee stock purchase plan that provides that eligible employees may contribute toward the purchase of our 

Class A common stock. These plans are described more fully in Note 9.

Earnings per Share

Basic earnings per share is computed by dividing net income by the weighted average number of common shares 

outstanding for that period less the weighted average number of unvested restricted shares outstanding for that 

period. Diluted earnings per share takes into account the effect of dilutive instruments, such as stock options, 

restricted stock and restricted stock units, and uses the average share price for the period in determining the 

number of common stock equivalents that are to be added to the weighted average number of shares outstanding. 

Common stock equivalents are excluded from the diluted earnings per share calculation if the effect would be anti-

dilutive. The following table summarizes the basic and diluted weighted average common shares (in thousands).

Weighted average shares outstanding 

Weighted average unvested restricted shares 

  Basic shares 

Effect of potentially dilutive securities: 

  Stock-based compensation awards 

Diluted weighted average common shares 

Anti-dilutive shares 

 Year Ended December 31,

2008  

2007  

2006

27,112  

(111) 

27,001  

26,716  

26,376

(32) 

—

26,684  

26,376

526  

576  

27,527  

27,260  

105  

279  

573

26,949

253

40  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Fair Value of Financial Instruments

For certain financial instruments, including cash and cash equivalents, short-term investments, accounts receivable, 

marketable securities, notes payable, and accounts payable, the carrying amounts approximate fair value.

The estimated fair value of financial instruments in the table below has been determined using available market 

information or other appropriate valuation methodologies. Estimates are not necessarily indicative of the amounts 

that could be realized in a current market exchange as considerable judgment is required in interpreting market 

data used to develop estimates of fair value. The use of different market assumptions or estimation techniques 

could have a material effect on the estimated fair value. Other assets includes some financial instruments that have 

fair values based on market quotations. The decline in Other assets is mainly related to our investment in Sartorius. 

Long-term debt has an estimated fair value based on quoted market prices for the same or similar issues.

The estimated fair value of our financial instruments is as follows (in millions):

Year Ended December 31,

2008 

2007

Carrying 
Amount 

Fair 
Value 

Carrying 
Amount 

Fair
Value

Other assets 

Total long-term debt 

$ 

79.8 

$  425.0 

$ 

78.2 

$  381.0 

$  111.9 

$  452.8 

$  173.2

$  446.0

We determine the fair value of an asset or liability based on the assumptions that market participants would use in 

pricing the asset or liability, not assumptions made by the reporting entity. The identification of market participant 

assumptions provides a basis for determining what inputs are to be used for pricing each asset or liability. Statement  

of Financial Accounting Standards (SFAS) 157 establishes a fair value hierarchy which gives precedence to fair value 

measurements calculated using observable inputs to those using unobservable inputs. This hierarchy prioritizes the 

inputs into three broad levels as follows:

•	 Level 1  Quoted prices in active markets for identical securities

•	 Level 2  Other significant observable inputs (including quoted prices in active markets for similar securities)

•	 Level 3  Significant unobservable inputs (including our assumptions in determining the fair value of investments)

Financial assets carried at fair value as of December 31, 2008 are classified in the hierarchy as follows (in millions):

Short-term investments 

  Corporate obligations 

  Municipal obligations 

  Asset backed securities 

  U.S. Agencies 

  Marketable equity securities 

Long-term marketable equity securities 

Total   

Level 1 

Level 2 

Total

$ 

6.0 

$ 

— 

— 

— 

7.0 

13.0 

20.3 

$ 

1.0 

5.0 

12.5 

7.3 

0.2 

26.0 

— 

$ 

33.3 

$ 

26.0 

$ 

7.0

5.0

12.5

7.3

7.2

39.0

20.3

59.3

Bio-Rad Laboratories  |  Annual Report 2008  :  41 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

Recent Financial Accounting Standards

In June 2008, the Financial Accounting Standards Board (FASB) issued FASB Staff Position (FSP) No. Emerging 

Issues Task Force (EITF) 03-6-1, Determining Whether Instruments Granted in Share-Based Payment Transactions 

Are Participating Securities. FSP No. EITF 03-6-1 concluded that unvested share-based payment awards that 

contain nonforfeitable rights to dividends or dividend equivalents (whether paid or unpaid) are participating securities 

and shall be included in the computation of basic earnings per share (EPS) pursuant to the two-class method.  

This FSP becomes effective for us on January 1, 2009. Early adoption of the FSP is not permitted; however, it will 

apply retrospectively to EPS data for all periods presented in the financial statements or in financial data. We do 

not currently expect that this FSP will have a material impact on our EPS data in fiscal year 2009 or on EPS for  

any prior periods.

In May 2008, the FASB issued SFAS 162, The Hierarchy of Generally Accepted Accounting Principles. SFAS 162 

identifies the sources of accounting principles and the framework for selecting principles to be used in the preparation 

and presentation of financial statements in accordance with generally accepted accounting principles in the United 

States of America. The adoption of SFAS 162 will not have an effect on our consolidated financial statements.

In March 2008, the FASB issued SFAS 161, Disclosures about Derivative Instruments and Hedging Activities—an 

amendment of SFAS 133. SFAS 161 seeks to improve financial reporting for derivative instruments and hedging 

activities by requiring enhanced disclosures regarding the impact on financial position, financial performance, and 

cash flows. SFAS 161 is effective for us on January 1, 2009. Since SFAS 161 requires only additional disclosures 

concerning derivatives and hedging activities, the adoption of SFAS 161 will not affect our financial condition, 

results of operations or cash flows.

As amended in February 2008 by FSP No. FAS 157-2, Effective Date of FASB Statement No. 157, SFAS 157, Fair 

Value Measurements, defines fair value, establishes a framework for measuring fair value and expands disclosures 

about fair value measurements. FSP FAS 157-2 defers the effective date of SFAS 157 for all nonfinancial assets 

and liabilities, except those items recognized or disclosed at fair value on an annual or more frequently recurring 

basis, until January 1, 2009. As such, we partially adopted the provisions of SFAS 157 effective January 1, 2008. 

We expect to adopt the remaining provisions of SFAS 157 beginning in 2009. We expect the adoption of SFAS 157 

to impact the way in which we calculate fair value for our annual impairment review of goodwill and non-amortizable 

intangible assets, and when conditions exist that require us to calculate the fair value of long-lived assets; however, 

we do not expect this adoption to have a material impact on our consolidated financial statements.

In December 2007, the FASB issued SFAS 141R, Business Combinations. SFAS 141R continues to require the 

purchase method of accounting to be applied to all business combinations, but it significantly changes the 

accounting for certain aspects of business combinations. Under SFAS 141R, an acquiring entity will be required 

to recognize all the assets acquired and liabilities assumed in a transaction at the acquisition-date fair value with 

limited exceptions. SFAS 141R will change the accounting treatment for certain specific acquisition related items 

including: (1) expensing acquisition related costs as incurred; (2) valuing noncontrolling interests at fair value at  

the acquisition date; and (3) expensing restructuring costs associated with an acquired business. SFAS 141R  

also includes a substantial number of new disclosure requirements. SFAS 141R is to be applied prospectively to 

business combinations for which the acquisition date is on or after January 1, 2009. We expect SFAS 141R will 

have an impact on our accounting for future business combinations once adopted but the effect is dependent 

upon the acquisitions that are made in the future.

42  :  Bio-Rad Laboratories  |  Annual Report 2008

In December 2007, SFAS 160, Noncontrolling Interests in Consolidated Financial Statements, was issued. SFAS 160 

establishes new accounting and reporting standards for the noncontrolling interest in a subsidiary and for the decon-

solidation of a subsidiary. It clarifies that a noncontrolling interest in a subsidiary (minority interest) is an ownership 

interest in the consolidated entity that should be reported as equity in the consolidated financial statements and 

separate from the parent company’s equity. Among other requirements, this statement requires consolidated net 

income to be reported at amounts that include the amounts attributable to both the parent and the noncontrolling 

interest. It also requires disclosure, on the face of the consolidated statement of income, of the amounts of consolidated 

net income attributable to the parent and to the noncontrolling income interest. This statement is effective for us on 

January 1, 2009. When implemented, prior periods will be recast for the changes required by SFAS 160. The adoption 

of this standard will not have a material impact on our consolidated financial statements.

2. ACQUISITIONS

DiaMed Holding AG (“DiaMed”) develops manufactures and markets worldwide a complete line of reagents used 

in blood typing and screening as well as instruments and instrument systems that use its proprietary reagents. Its 

products are used by hospitals, clinical laboratories and blood banks to identify certain properties of the cell and 

serum components of human blood prior to a blood transfusion. On October 1, 2007, we acquired approximately 

85.96% of the outstanding shares of DiaMed for approximately $399.3 million. In March 2008, we acquired an 

additional 556 shares of DiaMed for approximately $14 million, with a second payment to be paid when the final 

tender offer is made to the remaining minority shareholders. In December 2008 we acquired an additional 600 

shares of DiaMed for approximately $19.6 million. As of December 31, 2008, our total ownership of the outstanding 

shares of DiaMed amounted to 93.46%. The total purchase to date of approximately $432.9 million includes  

$38.1 million of net tangible assets, $202.0 million of goodwill, and $192.8 million of intangible assets. The goodwill 

is not deductible for tax purposes. The allocation of the total purchase price to net tangible assets, goodwill and 

other intangible assets has been recorded at their fair market value based upon management estimates except for 

the minority interest share in such assets and liabilities which was recorded at historical cost. The results of this 

acquisition are included in our consolidated financial statements beginning with the fourth quarter of 2007,  

in our Clinical Diagnostics segment. In connection with the original acquisition of DiaMed we recorded acquisition 

liabilities related to the termination of a small number of DiaMed employees of $4.9 million. During the year ended 

December 31, 2008, we paid approximately $3.1 million related to these termination liabilities. There were no payments 

made during the year ending December 31, 2007.

The remaining 1,000 outstanding shares of DiaMed are held by multiple minority shareholders. Their interest is 

recorded as Minority Interests on the consolidated balance sheet. We are obligated to submit a cash tender offer to 

acquire the remaining 6.54% of shares from the minority shareholders for 92.25% of the price paid to the majority 

shareholders. Based on December 31, 2008 foreign exchange rates, we estimate the offer would require approximately 

$38 million if fully accepted. The minority shareholders are under no obligation to accept our tender offer. The acquisition 

of the minority shares will be accounted for as a step acquisition if, and when, such shares are acquired.

In December 2008, we acquired 100% of the shares of DiaMed Fennica Oy (Fennica) and 100% of the shares of 

DiaMed (G.B.) Limited. These companies were independent distributors of DiaMed products and will be included 

in our Clinical Diagnostics segment. The total cash purchase price of these acquisitions was approximately  

$17.0 million. We acquired $3.3 million of net tangible liabilities, $7.4 million of goodwill and $12.9 million of intangible 

assets. The goodwill will not be deductible for tax purposes. We are in the process of finalizing the allocation of the 

purchase price to the individual assets acquired and liabilities assumed. The preliminary allocation of the purchase

Bio-Rad Laboratories  |  Annual Report 2008  :  43 

noteS to conSoLidA ted finAnciAL St AtementS  (continued)

price included in the current period balance sheet is based on the best estimates of management. The completion  

of the purchase price allocation is pending the finalization of certain analyses of inventory, taxes and liabilities. The 

final allocation may result in adjustments to the carrying value of the recorded assets and liabilities, revisions of the 

useful lives of intangible assets and the determination of any residual amount that will be allocated to goodwill. The 

related depreciation and amortization from the acquired assets is also subject to revision based on the final allocation.

In November 2006, we acquired Ciphergen Biosystems, Inc.’s (Ciphergen) ProteinChip Systems business and 

worldwide rights to its Surface Enhanced Laser Desorption/Ionization (SELDI) technology for approximately  

$20 million in cash. The acquisition includes certain product lines, manufacturing capability, and intellectual property 

as well as access to Ciphergen’s life science customer base. Under the terms of the agreement, Ciphergen will 

retain rights to the diagnostics market. Through a separate supply agreement, Bio-Rad supplies instruments and 

reagents to Ciphergen to support their diagnostics business. The total purchase of $20.0 million included  

$5.4 million of net tangible assets, $3.0 million of goodwill and $11.6 million of intangible assets. The goodwill will 

be deductible for tax purposes. An initial amount of $18.0 million was paid in 2006. An additional $2.0 million was 

paid in 2007 after the SELDI patent was granted. This $2.0 million is shown as additional goodwill in 2007. Purchased 

in-process research and development of $3.8 million was charged to expense in the fourth quarter of 2006. The 

allocation of the total purchase price to net tangible assets, goodwill and other intangible assets has been recorded 

at their fair market value based upon management estimates. The results of this acquisition are included in our 

consolidated financial statements from the acquisition date, in our Life Science segment.

3. AVAILABLE-FOR-SALE INVESTMENTS

Available-for-sale investments consist of the following (in millions): 

Current:

  Corporate obligations 

  Municipal obligations 

  Asset backed securities (including mortgage-backed) 

  U.S. Agencies 

  Marketable equity securities 

Long-term:

  Marketable equity securities 

Total   

 December 31,

2008 

2007

$ 

7.0 

5.0 

12.5 

7.3 

7.2 

39.0  

20.3 

$ 

10.3

 —

 —

34.5

17.2

62.0

47.7

$ 

59.3 

$  109.7

At December 31, 2008 we had total accumulated unrealized losses of $13.2 million and no accumulated unrealized 

gains. At December 31, 2007 we had accumulated unrealized losses of $1.1 million and accumulated unrealized 

gains of $26.7 million. The fair value of our available-for-sale investments has declined due to a number of factors, 

including changes in interest rates, changes in economic conditions and changes in market outlook for various 

industries, among others. Because Bio-Rad has the ability to hold these investments until a recovery of fair value, 

or for a reasonable period of time sufficient for a forecasted recovery of fair value, which may be maturity, we do 

not consider these investments to be other-than-temporarily impaired at December 31, 2008. 

44  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
In 2008, we recognized $9.6 million of other-than-temporary impairment losses on available-for-sale investments. 

In light of continuing declines in their market price, we no longer believe that these investments will recover in the 

foreseeable future. No securities were considered other-than-temporarily impaired in 2007 or 2006.

4. INVESTMENTS

We own shares of ordinary voting stock of Sartorius AG, of Goettingen, Germany, a process technology supplier to 

the biotechnology, pharmaceutical, chemical and food and beverage industries. We purchased shares for approximately  

$1 million in both 2008 and 2007, bringing our total investment to approximately 28% of the outstanding voting 

shares of Sartorius at December 31, 2008. The Sartorius family trust and Sartorius family members hold a controlling 

interest of the outstanding voting shares. We do not have any representative or designee on Sartorius’ board of 

directors, nor do we have any other influence over the operating and financial policies of Sartorius. Therefore, we 

account for this investment using the cost method. This investment is reported in Other assets.

During July 2006, Accent Semiconductor Technology Inc. (Accent), a private company, was acquired by Nanometrics 

Inc. (Nanometrics), a publicly held company. In preparation for the merger, Accent repaid the $11.8 million note receivable 

and accrued interest owed to Bio-Rad as part of Accent’s 2000 purchase of the assets and certain liabilities of our 

former semiconductor and optoelectronic metrology business. As part of the merger agreement, we tendered our 

ownership interest in Accent in exchange for approximately 600,000 shares of Nanometrics stock valued at $5.4 million 

on conversion. We also received a $2.5 million facilitation fee for aiding in the merger. These transactions resulted in a 

gain of $4.7 million included in Other income, net (see Note 10) in 2006. Our current ownership interest in Nanometrics 

is less than 5%, is marked to market and is included in Other assets. At December 31, 2008 we recognized $4.5 million 

of impairment expense related to Nanometrics.

5. GOODWILL AND OTHER PURCHASED INTANGIBLE ASSETS

Goodwill balances have been included in Corporate for segment reporting purposes in Note 14. Changes to Goodwill 

were as follows (in millions):

January 1 

  DiaMed acquisition/additional share purchase 

  DiaMed purchase accounting true-ups 

  Distributor acquisitions 

Impairment 

  Ciphergen acquisition 

  Currency fluctuations/other 

December 31 

  2008  

  2007

$  328.4  

$  119.5

  12.2  

  201.4

(11.6) 

7.4  

(27.2) 

  —  

  12.6  

 —

 —

—

2.0

5.5

$  321.8  

$  328.4

As part of the acquisition of DiaMed in October 2007 and the purchase of additional shares in March and December 

2008, (see Note 2), we added net $202.0 million of goodwill and $192.8 million of intangible assets: $72.6 million of 

customer relationships, $81.1 million of know how, $17.0 million of tradenames, $18.7 million of developed product 

technology and $3.4 million of licenses.

Bio-Rad Laboratories  |  Annual Report 2008  :  45 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

In 2008, the purchase price allocation related to the DiaMed acquisition was finalized. The completion of the 

purchase price allocation involved certain analyses of inventory, taxes and external valuations for certain fixed 

assets and property. The final revisions included adjustments to the carrying value of DiaMed’s recorded assets 

and liabilities and related depreciation and amortization, with the residual amount being allocated to goodwill. 

Some estimated acquisition liabilities were settled without requiring payment, additional collections were made  

on opening balance receivables, and an increase in work in process inventory was recorded.

As part of the acquisition of two distributors in December 2008 (see Note 2), we added $7.4 million of goodwill  

and $12.9 million of intangible assets: $2.9 million of tradenames, $2.3 million of covenants not to compete and 

$7.7 million of customer relationships.

During the fourth quarter of 2008, a $27.2 million impairment loss related to goodwill was recorded in the Life Science 

segment. The goodwill was originally recorded as part of an acquisition in 1999. The impairment was caused primarily 

by the continuing decline in sales of the BSE (bovine spongiform encephalopathy) product line.

Other than goodwill, we have no intangible assets with indefinite lives. Information regarding our identifiable purchased 

intangible assets is as follows (in millions):

Average 
  Remaining  
  Life (years) 

2-15 

1-8 

1-13 

3-11 

4-13 

3-10 

2 

3 

 December 31, 2008

Carrying  
Amount  

 Accumulated  
  Amortization  

Net 

$ 

83.4 

$ 

7.6 

$ 

75.8 

90.8 

44.7 

37.5 

21.1 

4.9 

1.0 

0.1 

18.9 

12.6 

8.8 

4.2 

2.1 

0.6 

0.1 

71.9 

32.1 

28.7 

16.9 

2.8 

0.4 

—  

$  283.5  

$ 

54.9  

$  228.6 

 December 31, 2007

Average 
  Remaining 
  Life (years) 

Carrying 
Amount 

 Accumulated 
  Amortization 

1-16 

1-9 

1-14 

1-12 

5-14 

1-4 

3 

4 

$ 

71.0 

$ 

81.4 

44.3 

20.4 

   16.2 

2.4 

1.0 

0.1 

2.0 

9.7 

7.6 

4.3 

0.8 

1.6 

0.4 

0.1 

Net 

$ 

69.0 

71.7 

36.7 

16.1 

15.4 

0.8 

0.6 

—  

$  236.8 

$ 

26.5 

$  210.3 

Customer relationships/lists 

Know how 

Developed product technology 

Licenses 

Tradenames 

Covenants not to compete 

Patents 

Other  

Customer relationships/lists 

Know how 

Developed product technology 

Licenses 

Tradenames 

Covenants not to compete 

Patents 

Other  

46  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
During the fourth quarter of 2008, $1.6 million of impairment losses related to intangible assets were recorded in   
During the fourth quarter of 2008, $1.6 million of impairment losses related to intangible assets were recorded in 

of certain product lines that were acquired in 2006.
the Life Science segment. The intangible asset impairment related to the developed technology intangible assets  

of certain product lines that were acquired in 2006.

Recorded purchased intangible asset amortization expense for the years ended December 31, 2008, 2007, and 

2006 was $29.8 million, $12.8 million, and $5.3 million, respectively. Estimated purchased intangible asset amortization 
Recorded purchased intangible asset amortization expense for the years ended December 31, 2008, 2007, and 

expense (based on existing intangible assets) for the years ended December 31, 2009, 2010, 2011, 2012 and 2013 
2006 was $29.8 million, $12.8 million, and $5.3 million, respectively. Estimated purchased intangible asset amortization 

is $32.1 million, $30.6 million, $29.3 million, $27.4 million and $24.7 million, respectively. 
expense (based on existing intangible assets) for the years ended December 31, 2009, 2010, 2011, 2012 and 2013 

is $32.1 million, $30.6 million, $29.3 million, $27.4 million and $24.7 million, respectively. 

6. NOTES PAYABLE AND LONG-TERM DEBT

6. NOTES PAYABLE AND LONG-TERM DEBT
Notes payable include local credit lines maintained by our subsidiaries aggregating approximately $27.5 million,  

Notes payable include local credit lines maintained by our subsidiaries aggregating approximately $27.5 million,  
of which $20.3 million was unused at December 31, 2008. At December 31, 2007, these lines aggregated approximately 

of which $20.3 million was unused at December 31, 2008. At December 31, 2007, these lines aggregated approximately 
$52.0 million, of which $42.1 million was unused. The weighted average interest rate on these lines was 4.1%  

$52.0 million, of which $42.1 million was unused. The weighted average interest rate on these lines was 4.1%  
and 3.9% at December 31, 2008 and 2007, respectively. Bio-Rad guarantees most of these credit lines.

and 3.9% at December 31, 2008 and 2007, respectively. Bio-Rad guarantees most of these credit lines.

The principal components of Long-term debt are as follows (in millions):

The principal components of Long-term debt are as follows (in millions):

 December 31,

2008  

 December 31,

2007

7.5% Senior Subordinated Notes  

7.5% Senior Subordinated Notes  
6.125% Senior Subordinated Notes 

6.125% Senior Subordinated Notes 
Other debt 

Other debt 
Capitalized leases 

Capitalized leases 

Less current maturities 

Less current maturities 
Long-term debt 

Long-term debt 

2008  

$  225.0  

$  225.0  
  200.0  

  200.0  
0.4  

0.4  
  27.8  

  27.8  
  453.2  

  453.2  
(7.2) 

(7.2) 
$  446.0  

$  446.0  

2007

$  225.0

$  225.0
  200.0

  200.0
0.4

0.4
27.4

27.4
  452.8

  452.8
(11.0)

(11.0)
$  441.8 

$  441.8 

In September 2007, Bio-Rad entered into Amendment No. 2 to the Amended and Restated Credit Agreement  

In September 2007, Bio-Rad entered into Amendment No. 2 to the Amended and Restated Credit Agreement  
(the “Credit Agreement”). Amendment No. 2 amends certain provisions of the Credit Agreement including increasing 

(the “Credit Agreement”). Amendment No. 2 amends certain provisions of the Credit Agreement including increasing 
the amount of borrowings permissible under the Credit Agreement to $200 million from $150 million, which may be 

the amount of borrowings permissible under the Credit Agreement to $200 million from $150 million, which may be 
increased up to an additional $50 million under certain conditions, and amending certain covenants to permit the 

increased up to an additional $50 million under certain conditions, and amending certain covenants to permit the 
acquisition by Bio-Rad of DiaMed including, but not limited to, the incurrence of certain indebtedness and liens in 

acquisition by Bio-Rad of DiaMed including, but not limited to, the incurrence of certain indebtedness and liens in 
connection with such acquisition.

connection with such acquisition.

Borrowings under the Credit Agreement are on a revolving basis and can be used to make acquisitions, for working 

Borrowings under the Credit Agreement are on a revolving basis and can be used to make acquisitions, for working 
capital and other general corporate purposes. Borrowings under the Credit Agreement are payable on June 21, 2010. 

capital and other general corporate purposes. Borrowings under the Credit Agreement are payable on June 21, 2010. 
We had no outstanding balance as of December 31, 2008.

We had no outstanding balance as of December 31, 2008.

In December 2004, Bio-Rad sold $200.0 million principal amount of Senior Subordinated Notes due 2014  

In December 2004, Bio-Rad sold $200.0 million principal amount of Senior Subordinated Notes due 2014  
(6.125% Notes). The notes pay a fixed rate of interest of 6.125% per year. We have the option to redeem any or all of 

(6.125% Notes). The notes pay a fixed rate of interest of 6.125% per year. We have the option to redeem any or all of 
the 6.125% Notes at various declining redemption prices or at 100% of the principal amount plus the “applicable 

the 6.125% Notes at various declining redemption prices or at 100% of the principal amount plus the “applicable 
premium” (as defined by the indenture) along with accrued and unpaid interest and certain other charges depending 

premium” (as defined by the indenture) along with accrued and unpaid interest and certain other charges depending 
on the date redeemed. Bio-Rad’s obligations under the 6.125% Notes are not secured, rank equal to other senior 

on the date redeemed. Bio-Rad’s obligations under the 6.125% Notes are not secured, rank equal to other senior 
subordinated notes and rank junior to all of Bio-Rad’s existing and future senior debt.

subordinated notes and rank junior to all of Bio-Rad’s existing and future senior debt.

Bio-Rad Laboratories  |  Annual Report 2008  :  47 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

In August 2003, Bio-Rad sold $225.0 million principal amount of Senior Subordinated Notes due 2013 (7.5% Notes). 

The notes pay a fixed rate of interest of 7.5% per year. We have the option to redeem any or all of the 7.5% Notes at 

various declining redemption prices or at 100% of the principal amount plus the “applicable premium” (as defined 

by the indenture) along with accrued and unpaid interest and certain other charges depending on the date redeemed. 

Bio-Rad’s obligations under the 7.5% Notes are not secured, rank equal to other senior subordinated notes and 

rank junior to all Bio-Rad’s existing and future senior debt.

The Credit Agreement is secured by substantially all of our personal property assets, the assets of our domestic 

subsidiaries and 65% of the capital stock of certain foreign subsidiaries. It is guaranteed by all of our existing and 

future material domestic subsidiaries. The Credit Agreement, the 6.125% Notes, and the 7.5% Notes require Bio-Rad 

to comply with certain financial ratios and covenants, among other things. The covenants include a leverage ratio 

test, an interest coverage test and a consolidated net worth test. There are also restrictions on our ability to declare 

or pay dividends, incur debt, guarantee debt, enter into transactions with affiliates, merge or consolidate, sell 

assets, make investments, create liens and prepay subordinated debt. We were in compliance with all financial 

ratios as of December 31, 2008 and 2007. 

Maturities of long-term debt at December 31, 2008 are as follows: 2009 – $7.2 million; 2010 – $4.1 million; 

2011 – $6.8 million; 2012 – $0.2 million; 2013 – $225.0 million; thereafter – $209.8 million.

7. INCOME TAXES

The U.S. and international components of income before taxes and minority interests are as follows (in millions):

 Year Ended December 31,

  2008  

  2007  

  2006 

$  52.7  

$  75.5  

$ 

66.8 

  90.1  

  45.3  

75.2 

$  142.8  

$  120.8  

$  142.0 

 Year Ended December 31,

2008  

2007  

2006 

$  28.3  

$  13.9  

$ 

12.0

4.0  

  15.2  

  47.5  

1.1  

  12.6  

  27.6  

2.6  

(5.9) 

(3.3) 

0.4  

(1.3) 

(4.6) 

(5.9) 

4.8  

1.2

24.6

37.8

0.8

0.2

1.0

 —

$  44.6  

$  26.5  

$ 

38.8

U.S.   

International 

Income before taxes and minority interests 

The provision for income taxes consists of the following (in millions):

Current tax expense  

  U.S. Federal 

  State 

International 

  Current tax expense 

Deferred tax expense (benefit) 

  U.S. and State 

International 

  Deferred tax expense (benefit) 

Non-current tax expense 

Provision for income taxes 

48  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
The reconciliation between Bio-Rad’s effective tax rate on income before taxes and minority interests and the  

statutory tax rate is as follows:

U. S. statutory tax rate 

Foreign income at other than U.S. tax rates 

Foreign losses not benefited 

Non-taxable dividend income 

Export sales benefit 

Research and development tax credits 

Increase in tax reserves 

Change in valuation allowance  

Examination settlements 

Foreign tax credit claims 

In-process research and development 

Goodwill impairment 

Other  

Provision for income taxes 

 Year Ended December 31,

2008  

35% 

2007   

35% 

2006

35%

(4) 

2  

(4) 

—  

(9) 

1  

3  

—  

—  

—  

7  

—  

(2) 

3  

(5) 

—  

(8) 

3  

(3) 

(2) 

(3) 

2  

—  

2  

31% 

22% 

(1)

1

(3)

(2)

(2)

1

1

(1)

—

—

—

(2)

27%

Deferred income taxes reflect the net tax effect of temporary differences between the carrying amounts of assets  

and liabilities for financial reporting purposes and the amounts used for income tax purposes. Significant components  

of deferred tax assets and liabilities are as follows (in millions):

  Year Ended December 31,

2008   

2007

Deferred tax assets

  Receivable allowances 

Inventory reserve 

  Warranty reserve 

  Vacation pay reserve 

  Net operating loss 

Impaired investments 

  Unrealized holding losses 

  Retirement reserve 

  Depreciation 

  Goodwill and intangibles 

  State tax credit carryforward 

  Other 

  Valuation allowance 

Deferred tax liabilities 

  Unrealized holding gains 

  Deferred gain 

  Foreign exchange gain/loss 

  Depreciation 

  Goodwill and intangibles 
  Other 

$ 

6.0  

$ 

  15.3  

8.1  

7.9  

  20.8  

7.6  

4.9  

5.4  

5.0  

  16.4  

8.1  

  18.1  

(40.7) 

  82.9  

  —  

5.1  

2.4  

7.4  

  52.1  
  12.9  

  79.9  

Net deferred taxes 

$ 

3.0  

$ 

5.4

14.6

7.3

7.4

20.9

3.5

—

5.8

5.9

16.9

7.5

16.7

(31. 1)

80.8

9.4

5.2

2.4

4.1

49.1
7.1

77.3

3.5

Bio-Rad Laboratories  |  Annual Report 2008  :  49 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

At December 31, 2008, Bio-Rad’s international subsidiaries had combined net operating loss carryforwards of 

$74.1 million. The amount of carryforwards subject to expiration includes $6.0 million, $8.9 million and $4.8 million 

in 2013, 2014 and 2015, respectively. The remaining loss carryforwards have no expiration date. The utilization 

of these carryforwards is limited to the separate taxable income of each individual subsidiary. We believe that it 

is more likely than not that the benefit from certain of these net operating loss carryforwards will not be realized. 

We have provided a valuation allowance of $17.6 million on the deferred tax assets relating to these net operating 

loss carryforwards. If or when recognized, the tax benefits relating to any reversal of the valuation allowance on 

deferred tax assets at December 31, 2008 will be recognized as a reduction of income tax expense.

At December 31, 2008, Bio-Rad had U.S. Federal net operating loss carryforwards of $8.6 million as a result of  

an acquisition. The utilization of these net operating loss carryforwards is subject to annual limitations. The loss 

carryforward will expire in the year 2018.

At December 31, 2008, Bio-Rad had a California research and experimental tax credit carryforward of $8.1 million 

which has no expiration date. Based on our judgment and consistent with prior years, we believe that it is more 

likely than not that the benefit from these tax credit carryforwards will not be realized. Therefore, we have provided 

a full valuation allowance against the deferred tax asset. The tax benefits relating to any reversal of the valuation 

allowance will be recognized as a reduction of income tax expense if and when it becomes realizable.

The change in the total valuation allowance against our deferred tax assets was a net increase of $9.6 million 

primarily due to our inability to generate capital gains to offset our investment impairments and unrealized holding 

losses on available for sale securities.

During 2008, the IRS has continued the audit of our Federal tax returns for 2004 and 2005. The examination will, 

however, cover tax years 2001 through 2005 as we have filed amended U.S. tax returns for these years and have 

credits generated in prior years which are being utilized in the years subject to examination by the IRS. We believe 

appropriate provisions for all outstanding issues have been made for all jurisdictions and all open years. We do not 

expect that the results of this examination will have a ma terial effect on our financial condition or results of operations.

We are subject to tax audits on various tax matters around the world.

The following table summarizes the open tax years by major tax jurisdiction that are subject to examination by tax 

authorities as of December 31, 2008:

U.S. 

France 

Germany 

Italy 

Japan 

Switzerland 

2001-2008

2006-2008

2004-2008

2002-2008

2004-2008

2007-2008

50  :  Bio-Rad Laboratories  |  Annual Report 2008

The following is a tabular reconciliation of the total amounts of unrecognized tax benefits for the year (in millions):

Unrecognized tax benefit—January 1 

Additions to tax positions related to prior years 

Reductions to tax positions related to prior years 

Additions/(Reductions) to tax positions related to the current year 

Settlements 

Lapse of statute of limitations 

Acquisitions 

Currency translation 

2008  

2007

$  22.3  

$ 

13.3

1.9  

(0.7) 

2.4  

(4.3) 

(2.6) 

  —  

(0.9) 

1.1

(2.4)

11.0

(2.5)

(1.4)

2.9

0.3

Unrecognized tax benefit—December 31 

$  18.1  

$ 

22.3

Included in the balance of unrecognized tax benefits at December 31, 2008 and 2007 respectively, are $17.1 million 

and $19.1 million of tax benefits that, if recognized, would affect the effective tax rate. Also included in the balance 

of unrecognized tax benefits at December 31, 2008 and 2007 respectively, are $1.1 million and $0.3 million of tax 

benefits that, if recognized, would result in adjustments to other tax accounts, primarily deferred taxes.

Bio-Rad recognizes accrued interest and penalties related to unrecognized tax benefits as income tax expense. 

Related to the unrecognized tax benefits noted above, Bio-Rad accrued interest of $2.4 million during 2008. During 

2007, Bio-Rad accrued interest of $2.8 million.

We believe that it is reasonably possible that approximately $1.9 million of our currently remaining unrecognized tax 

benefits, each of which are individually insignificant, may be recognized by the end of 2009 as a result of the lapse 

of the statute of limitations. These benefits are related to uncertainty regarding sustainability of certain deductions 

and credits for tax years that remain subject to examination by the relevant tax authorities. As of December 31, 2007, 

we believed that it was reasonably possible that $6.4 million of our unrecognized tax benefits may be recognized 

by the end of 2008 as a result of the lapse of the statute of limitations.

In general, it is our practice and intention to reinvest the earnings of our non-U.S. subsidiaries in their operations. 

As of December 31, 2008, Bio-Rad has not made a provision for U.S. or additional foreign withholding taxes on 

approximately $434 million of the excess of the amount for financial reporting over the tax basis of investments in 

foreign subsidiaries that are essentially permanent in duration. Generally, such amounts become subject to U.S. 

taxation upon remittance of dividends and under certain other circumstance. If these earnings were repatriated to 

the U.S., they would generate foreign tax credits that would reduce the U.S. federal tax liability associated with  

the distribution. The potential deferred tax liability for these earnings would be approximately $73 million.

8. STOCKHOLDERS’ EQUITY

Bio-Rad’s outstanding stock consists of Class A Common Stock (Class A) and Class B Common Stock (Class B). 

Each share of Class A and Class B participates equally in the earnings of Bio-Rad, and is identical in most respects 

except that Class A has limited voting rights. Each share of Class A is entitled to one-tenth of a vote on most 

matters, and each share of Class B is entitled to one vote. Additionally, Class A stockholders are entitled to elect 

25% of the Board of Directors and Class B stockholders are entitled to elect the balance of the directors. Cash 

dividends may be paid on Class A shares without paying a cash dividend on Class B shares but no cash dividend 

Bio-Rad Laboratories  |  Annual Report 2008  :  51 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

may be paid on Class B shares unless at least an equal cash dividend is paid on Class A shares. Class B shares 

are convertible at any time into Class A shares on a one-for-one basis at the option of the stockholder. The 

Schwartz family collectively holds a majority of Bio-Rad’s voting stock. As a result, the Schwartz family is able  

to exercise significant influence over Bio-Rad.

9. SHARE-BASED COMPENSATION/STOCK OPTION AND PURCHASE PLANS

Description of Share-Based Compensation Plans

Stock Option and Award Plans

We have three stock option plans for officers and certain other employees: the Amended 1994 Stock Option Plan 

(the “1994 Plan”); the 2003 Stock Option Plan (the “2003 Plan”); and the 2007 Incentive Award Plan (the “2007 

Plan”). The 1994 Plan and 2003 Plan authorize the grant of incentive stock options and non-qualified stock options 

to employees. The 2007 Plan authorizes the grant of stock options, restricted stock awards, stock appreciation 

rights and other types of equity awards to employees. We no longer make stock option grants under the 1994 Plan 

or 2003 Plan. A total of 1,650,360 shares have been reserved for issuance of equity awards and may be of either 

Class A or Class B common stock. At December 31, 2008 there were 1,318,579 shares available to be granted.

Under these plans, Class A and Class B options have been granted at prices not less than fair market value on  

the date of grant. Generally, options granted have a term of 10 years and vest in increments of 20% per year over 

a five-year period on the yearly anniversary date of the grant. For options granted before January 1, 2001, options 

vested in increments of 25% over a four-year period on the yearly anniversary date of the grant. Stock awards 

issued under the 2007 Plan generally vest in increments of 20% per year over a five-year period on the yearly 

anniversary date of the grant.

Employee Stock Purchase Plan (ESPP)

We have an employee stock purchase plan which provides that eligible employees may contribute up to 10%  

of their compensation up to $25,000 annually toward the quarterly purchase of our Class A common stock.  

The employees’ purchase price is 85% of the lesser of the fair market value of the stock on the first business  

day or the last business day of each calendar quarter. We have authorized the sale of 2,390,000 shares of common 

stock under the ESPP.

Share-Based Compensation Expense

Included in our share-based compensation expense in 2008, 2007 and 2006 is the cost related to stock option 

grants and ESPP stock purchases. In 2008 and 2007, share-based compensation also includes the cost related  

to restricted stock and restricted stock unit awards issued in 2008 and 2007.

For 2008, 2007 and 2006, we recognized pre-tax share-based compensation expense of $7.3 million, $5.5 million 

and $5.4 million, respectively. We did not capitalize any share-based compensation expense. In accordance with 

SFAS 123(R), we recognize share-based compensation net of estimated forfeitures.

For options granted before January 1, 2006, we amortized the fair value on an accelerated basis. For options and 

awards granted after January 1, 2006, we amortized the fair value on a straight-line basis.  All stock compensation 

awards are amortized over the requisite service periods of the awards, which are generally the vesting periods.

52  :  Bio-Rad Laboratories  |  Annual Report 2008

Stock Options

The following table summarizes stock option activity.

Outstanding, January 1, 2006 

  Granted 

  Exercised 

  Forfeited/Expired 

Outstanding, December 31, 2006 

  Granted 

  Exercised 

  Forfeited/Expired 

Outstanding, December 31, 2007 

  Granted 

  Exercised 

  Forfeited/Expired 

Shares  

 1,589,206  

  313,233  

  (177,867) 

(56,803) 

 1,667,769  

59,000  

  (222,808) 

(15,686) 

 1,488,275  

59,000  

  (269,731) 

(23,417) 

  Weighted- 
Average 
Exercise 
Price 

  Weighted-
Average 
  Remaining 
  Contractual 
  Term (years) 

  Aggregate
Intrinsic
Value 
(in millions)

$  34.43

$  62.68

$  25.81

$  51.79

$  40.06

$  75.09

$  28.16

$  56.70

$  43.06

$  88.35

$  25.09

$  53.99

Outstanding, December 31, 2008 

 1,254,127  

$  48.84 

5.28  

$ 

34.0 

Vested and expected to vest,

  December 31, 2008 

Exercisable, December 31, 2008 

 1,229,977  

  828,458  

$  48.40 

$  40.36 

5.23  

4.40  

$ 

$ 

34.0 

29.0 

The following summarizes information about stock options outstanding at December 31, 2008:

Options Outstanding  

Options Exercisable

Number 
Outstanding 
at 12/31/08 

Weighted-Average
Remaining 
Contractual Life 
 (in years)  

 Weighted- 
  Average 
Exercise Price 

Number 
Exercisable 
at 12/31/08 

Weighted-
Average
Exercise Price

373,702 

352,171 

322,354 

205,900 

2.76 

5.13 

6.52 

8.18 

$  23.45 

$  50.80 

$  60.22 

$  73.79 

373,702 

274,982 

133,174 

46,600 

$  23.45

$  49.67

$  59.69 

$  65.90 

Range of Exercise Prices  

$10.75 – $35.50 

$36.00 – $56.40 

$57.49 – $62.47 

$63.00 – $88.48 

Intrinsic value for stock options is defined as the difference between the current market value and the grant price. 

The total intrinsic value on the date of exercise of stock options exercised during 2008, 2007 and 2006 was approximately 

$17 million, $13 million and $8 million, respectively.

Bio-Rad Laboratories  |  Annual Report 2008  :  53 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

Cash received from stock options exercised during the years 2008, 2007 and 2006 was $6.8 million, $6.3 million and 
Cash received from stock options exercised during the years 2008, 2007 and 2006 was $6.8 million, $6.3 million and 

$4.6 million, respectively. The actual tax benefit realized for the tax deductions from stock options exercised totaled 
$4.6 million, respectively. The actual tax benefit realized for the tax deductions from stock options exercised totaled 

$6.3 million, $3.6 million and $1.8 million in 2008, 2007 and 2006, respectively. 
$6.3 million, $3.6 million and $1.8 million in 2008, 2007 and 2006, respectively. 

As of December 31, 2008, there was $7.4 million of total unrecognized compensation cost from stock options. That 
As of December 31, 2008, there was $7.4 million of total unrecognized compensation cost from stock options. That 

cost is expected to be recognized over a weighted-average period of approximately 2 years.
cost is expected to be recognized over a weighted-average period of approximately 2 years.

The weighted-average fair value for stock options granted was estimated using a Black-Scholes option-pricing 
The weighted-average fair value for stock options granted was estimated using a Black-Scholes option-pricing 

model with the following weighted-average assumptions:
model with the following weighted-average assumptions:

Expected volatility 
Expected volatility 

Risk-free interest rate 
Risk-free interest rate 

Expected life (in years) 
Expected life (in years) 

Expected dividend 
Expected dividend 

 Year Ended December 31,
 Year Ended December 31,

2008     
2008     

2007    
2007    

2006
2006

34% 
34% 

3.92% 
3.92% 

8.5     
8.5     

—     
—     

34% 
34% 

4.72% 
4.72% 

8.5    
8.5    

—    
—    

36%
36%

4.62%
4.62%

7.4 
7.4 

—
—

Weighted-average fair value of options granted 
Weighted-average fair value of options granted 

$  42.21    
$  42.21    

$ 
$ 

37.05    
37.05    

$  29.85
$  29.85

Volatility was based on the historical volatilities of our common stock for a period equal to the stock option’s 
Volatility was based on the historical volatilities of our common stock for a period equal to the stock option’s 

expected life. The risk-free interest rate is based on the U.S. Treasury yield curve in effect at the time of the grant. 
expected life. The risk-free interest rate is based on the U.S. Treasury yield curve in effect at the time of the grant. 

In 2008 and 2007 the expected life represents the number of years that we estimate, based primarily on historical 
In 2008 and 2007 the expected life represents the number of years that we estimate, based primarily on historical 

experience, that the options will be outstanding prior to exercise. In 2006, we estimated the expected life using the 
experience, that the options will be outstanding prior to exercise. In 2006, we estimated the expected life using the 

simplified method described in the SEC’s Staff Accounting Bulletin No. 107. We do not anticipate paying any cash 
simplified method described in the SEC’s Staff Accounting Bulletin No. 107. We do not anticipate paying any cash 

dividends in the future and therefore use an expected dividend yield of zero.
dividends in the future and therefore use an expected dividend yield of zero.

Restricted Stock
Restricted Stock

Restricted stock was granted in 2008 and 2007 under the 2007 Plan. The fair value of each share of restricted stock  
Restricted stock was granted in 2008 and 2007 under the 2007 Plan. The fair value of each share of restricted stock  

is the market value as determined by the closing price of the stock on the day of grant.
is the market value as determined by the closing price of the stock on the day of grant.

The following table summarizes restricted stock activity:
The following table summarizes restricted stock activity:

Nonvested shares, at beginning of year  
Nonvested shares, at beginning of year  

Granted  
Granted  

Vested  
Vested  

Cancelled/Forfeited  
Cancelled/Forfeited  

Nonvested shares, at end of year  
Nonvested shares, at end of year  

 Year Ended December 31,
 Year Ended December 31,

2008 
2008 

2007
2007

Restricted  
Restricted  
Stock  
Stock  
Shares  
Shares  

75,720  
75,720  

78,485  
78,485  

(14,625) 
(14,625) 

(3,666) 
(3,666) 

135,914  
135,914  

Weighted-Average  
Weighted-Average  
Grant-Date  
Grant-Date  
 Fair Value  
 Fair Value  

Restricted   Weighted-Average
Restricted   Weighted-Average
Grant-Date
Grant-Date
Fair Value
Fair Value

Stock  
Stock  
 Shares   
 Shares   

$  75.33 —
$  75.33 

—  

 —
 —

$  88.09 
$  88.09 

$  75.33 
$  75.33 

$  77.24 
$  77.24 

$  82.64 
$  82.64 

75,970  
75,970  

$  75.33
$  75.33

—  
—  

(250)  
(250)  

75,720   
75,720   

 —
 —

$  75.32
$  75.32

$  75.33
$  75.33

As of December 31, 2008, there was approximately $8.4 million of total unrecognized compensation cost related  
As of December 31, 2008, there was approximately $8.4 million of total unrecognized compensation cost related  

to restricted stock granted under the 2007 Plan. The cost is expected to be recognized over a weighted-average 
to restricted stock granted under the 2007 Plan. The cost is expected to be recognized over a weighted-average 

period of approximately 4 years.
period of approximately 4 years.

54  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
Restricted Stock Units

Restricted stock units, which are rights to receive shares of company stock, were granted during 2008 and 2007 

under the 2007 Plan. The fair value of each restricted stock unit is the market value as determined by the closing 

price of the stock on the day of grant.

The following table summarizes restricted stock unit activity:

Outstanding, January 1, 2007  

  Granted  

  Vested  

  Cancelled/Forfeited  

Outstanding, December 31, 2007 

  Granted  

  Vested  

  Cancelled/Forfeited  

Outstanding, December 31, 2008 

Expected to vest, December 31, 2008 

Weighted-Average  
Grant-Date  
 Fair Value  

 —

$  75.32

 —

$  75.32

$  75.32

$  88.00

$  75.32

$  79.58

Restricted  
Stock  
 Units  

—  

28,010  

—  

(1,260) 

26,750  

37,445  

(2,593) 

(953) 

60,649  

54,306  

Weighted-Average  
Remaining  

Aggregate
Intrinsic Value
Contractual Term   as of December 31,
2008 (in millions)

(in years)  

2.29  

2.20  

$  4.6

$  4.1

As of December 31, 2008 there was approximately $3.5 million of total unrecognized compensation cost related to 

restricted stock units granted under the 2007 Plan. That cost is expected to be recognized over a weighted-average 

period of approximately 4 years. 

Employee Stock Purchase Plan

The fair value of the employees’ purchase rights was estimated using a Black-Scholes model with the following 

weighted-average assumptions:

Expected volatility 

Risk-free interest rate 

Expected life (in years) 

Expected dividend 

 Year Ended December 31,

2008    

37% 

1.87% 

.25     

—     

2007    

29% 

4.79% 

.25     

—     

2006

28%

4.66%

.25

—

Weighted-average fair value of purchase rights 

$  20.79     

$  17.05     

$  13.68

The major assumptions are primarily based on historical data. Volatility was based on the historical volatilities of  

our common stock for a period equal to the expected life of the purchase rights. The risk-free interest rate is based 

on the U.S. Treasury yield curve in effect at the time of the grant. We do not anticipate paying any cash dividends  

in the future and therefore use an expected dividend yield of zero.

We sold 88,533 shares for $6.1 million, 81,388 shares for $5.3 million, and 99,888 shares for $5.3 million under the 

ESPP to employees in 2008, 2007 and 2006, respectively. At December 31, 2008, 337,629 shares remain authorized 

under the ESPP.

We currently issue new shares to satisfy stock option exercises, restricted stock issuances and ESPP stock purchases.

Bio-Rad Laboratories  |  Annual Report 2008  :  55 

 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

10. OTHER INCOME AND EXPENSE

Other income, net includes the following income (expense) components (in millions):

Interest and investment income 

Net realized gains (losses) on investments 

Other-than-temporary impairment on investments 

Write-down of investments 

Gain on sale of investment (Note 4) 

Miscellaneous other items 

Other income (expense), net 

11. SUPPLEMENTAL CASH FLOW INFORMATION

 Year Ended December 31,

2008  

2007  

2006

$  10.6  

$  21.5  

$ 

22.2 

(0.7) 

(9.6) 

(1.3) 

0.5  

 —   

(3.6) 

  —  

 —   

0.6  

1.4  

0.1 

— 

— 

4.7 

2.0 

$ 

(0.4) 

$  19.8  

$ 

29.0 

The reconciliation of net income to net cash provided by operating activities is as follows (in millions):

Net Income  

Adjustments to reconcile net income to net cash 

  provided by operating activities (net of effects of acquisitions):

  Depreciation 

  Amortization 

  Minority interests 

  Excess tax benefits from share-based compensation 

  Share-based compensation 

  Foreign currency economic hedge transactions, net 

  Losses (gains) on dispositions of securities 

  Decrease (increase) in accounts receivable, net 

  Decrease (increase) in inventories, net 

  Decrease (increase) in other current assets 

  Decrease (increase) in accounts payable and other current liabilities 

Increase (decrease) in income taxes payable 

Increase (decrease) in deferred taxes 

  Litigation settlement related to MJ acquisition 

  Goodwill and purchased intangible asset impairments 

  Other 

 Year Ended December 31,

2008  

2007  

2006

$  89.5  

$  93.0  

$  103.3 

  66.3  

  30.8  

  53.5  

  13.8  

8.8  

(5.1) 

7.3  

5.4  

  10.6  

  11.1  

(51.9) 

(0.6) 

(3.6) 

(1.6) 

(3.2) 

  —  

  28.8  

(1.2) 

1.3  

(3.0) 

5.5  

4.1  

(0.5) 

9.0  

4.4  

(2.8) 

  10.6  

(10.1) 

(5.9) 

 —   

 —   

  18.7  

48.7 

6.7 

— 

(1.4)

5.4 

2.2 

(0.1)

(25.5)

(22.8)

16.9 

17.3 

3.8 

1.2 

(47.0)

— 

9.5 

Net cash provided by operating activities 

$ 

191.4  

$ 

191.6  

$ 

118.2 

56  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
12. COMMITMENTS AND CONTINGENT LIABILITIES

Rents and Leases

Net rental expense under operating leases was $38.8 million in 2008, $32.8 million in 2007 and $26.7 million in 

2006. Leases are principally for facilities and automobiles.

Annual future minimum lease payments at December 31, 2008 under operating leases are as follows: 2009 – $31.7 million; 

2010 – $28.8 million; 2011 – $20.1 million; 2012 – $13.1 million; 2013 – $6.4 million; subsequent to 2013 – $8.0 million.

Deferred Profit Sharing Retirement Plan

We have a profit sharing plan covering substantially all U.S. employees. Contributions are made at the discretion of 

the Board of Directors. Bio-Rad has no liability other than for the current year’s contribution. Contributions charged 

to income were $10.5 million, $9.4 million, and $7.8 million in 2008, 2007, and 2006, respectively.

Other Post-Employment Benefits

In several foreign locations we are statutorily required to provide a lump sum severance or termination indemnity 

to our employees. Under these plans, the vested benefit obligation at December 31, 2008 and 2007 was $19.0 million 

and $19.4 million, respectively and has been included in Other long-term liabilities in the consolidated balance 

sheets. These plans are not required to be funded, and as such, there is no trust or other device used to accumulate 

assets to settle these obligations.

Foreign Exchange Contracts

We enter into forward foreign exchange contracts as an economic hedge against foreign currency denominated 

intercompany receivables and payables. At December 31, 2008, we had contracts maturing in January through 

March 2009 to sell foreign currency with a nominal value of $163.7 million and an unrealized loss of $0.1 million. 

Contracts to purchase foreign currency had a nominal value of $22.0 million with an unrealized gain of $0.1 million.

Insurance

We carry a deductible for workers’ compensation and a portion of our group health insurance cost. Accruals for 

losses are based on our claims experience and actuarial assumptions followed in the insurance industry. Should  

a greater amount of claims occur compared to our estimates or cost of medical care increase beyond what has 

been anticipated, reserves recorded may not be sufficient and additional charges to income may be required.

Letters of Credit

In the ordinary course of business, we are at times required to post letters of credit. The letters of credit are issued 

by our banks to guarantee our obligations to various parties including insurance companies. We were contingently 

liable for $12.5 million of standby letters of credit with banks as of December 31, 2008.

Bio-Rad Laboratories  |  Annual Report 2008  :  57 

 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

13. LEGAL PROCEEDINGS

On February 9, 2006, Bio-Rad completed negotiations with Applera Corporation (Applera) and Roche Molecular 

Systems, Inc. to settle the patent infringement litigation against MJ Research, Inc. (MJ Research) which Bio-Rad 

acquired in 2004. The total net settlement amount, including amounts related to previously accrued back royalties, 

was approximately $62 million. We recognized $1.2 million of additional expense in the fourth quarter of 2005 to 

adjust our estimated liability as a result of the settlements. In connection with the settlements, we entered into a 

royalty-bearing license agreement with Applera relating to our real-time instrument business in the United States 

and a term limited license in the rest of the world.

We are party to various claims, legal actions and complaints arising in the ordinary course of business. We do 

not believe that any ultimate liability resulting from any of these lawsuits will have a material adverse effect on our 

results of operations, financial position or liquidity. However, we cannot give any assurance regarding the ultimate 

outcome of these lawsuits and their resolution could be material to our operating results for any particular period, 

depending upon the level of income for the period.

14. SEGMENT INFORMATION

Bio-Rad is a multinational manufacturer and worldwide distributor of its own life science research products and 

clinical diagnostics products. We have two reportable segments: Life Science and Clinical Diagnostics. These 

reportable segments are strategic business lines that offer different products and services and require different 

marketing strategies.

The Life Science segment develops, manufactures, sells and services reagents, apparatus and instruments used 

for biological research. These products are sold to university and medical school laboratories, pharmaceutical and 

biotechnology companies, food testing laboratories and government and industrial research facilities.

The Clinical Diagnostics segment develops, manufactures, sells and services automated test systems, informatics 

systems, test kits and specialized quality controls for the healthcare market. These products are sold to reference 

laboratories, hospital laboratories, state newborn screening facilities, physicians’ office laboratories, transfusion 

laboratories, and insurance and forensic testing laboratories.

Other Operations include the remainder of our former Analytical Instruments segment.

The accounting policies of the segments are the same as those described in Significant Accounting Policies (see 

Note 1). Segment profit or loss used for corporate management purposes includes an allocation of corporate 

expense based upon sales and an allocation of interest expense based upon accounts receivable and inventories. 

Segments are expected to manage only assets completely under their control. Accordingly, segment assets 

include primarily accounts receivable, inventories and gross machinery and equipment. Goodwill balances have 

been included in corporate for segment reporting purposes.

58  :  Bio-Rad Laboratories  |  Annual Report 2008

Information regarding industry segments at December 31, 2008, 2007, and 2006 and for the years then ended  
Information regarding industry segments at December 31, 2008, 2007, and 2006 and for the years then ended  

is as follows (in millions):
is as follows (in millions):

Segment net sales 
Segment net sales 

Allocated interest expense 
Allocated interest expense 

Depreciation and amortization 
Depreciation and amortization 

Segment profit 
Segment profit 

Segment assets 
Segment assets 

Capital expenditures 
Capital expenditures 

Life 
Life 
Science 
Science 

Clinical  
Clinical  
  Diagnostics  
  Diagnostics  

Other 
Other 
  Operations 
  Operations 

$  643.5 
$  643.5 

$  615.1 
$  615.1 

  575.6 
$  575.6 

$ 1,106.4 
$ 1,106.4 

$  832.2 
$  832.2 

  684.9 
$  684.9 

$ 
$ 

$ 
$ 

$ 

$ 
$ 

$ 
$ 

$ 

10.5 
10.5 

12.2 
12.2 

13.0 
13.0 

17.5 
17.5 

19.1 
19.1 

18.0 
18.0 

$ 
$ 

$ 
$ 

$ 

$ 
$ 

$ 
$ 

$ 

21.4 
21.4 

19.2 
19.2 

18.8 
18.8 

74.9 
74.9 

44.8 
44.8 

33.8 
33.8 

$  13.3 (1) 
$  13.3 (1) 

$  139.8 
$  139.8 

$ 
$ 

24.7 
24.7 

$  80.7 (2) 
$  80.7 (2) 

  25.7 (3) 
$  25.7 (3) 

$ 

89.6 
89.6 

$  343.1 
$  343.1 

$  321.3 
$  321.3 

  318.5 
$  318.5 

$ 
$ 

$ 
$ 

$ 

10.6 
10.6 

8.9 
8.9 

10.3 
10.3 

$  675.2 
$  675.2 

$  677.1 
$  677.1 

  458.8 
$  458.8 

$ 
$ 

$ 
$ 

$ 

56.6 
56.6 

40.3 
40.3 

34.7 
34.7 

$ 
$ 

$ 
$ 

$ 

$ 
$ 

$ 
$ 

$ 

$ 
$ 

$ 
$ 

$ 

$ 
$ 

$ 
$ 

$ 

$ 
$ 

$ 
$ 

$ 

$ 
$ 

$ 
$ 

$ 

14.5
14.5

13.8
13.8

13.4
13.4

0.2
0.2

0.2
0.2

0.2
0.2

0.1
0.1

0.1
0.1

0.3
0.3

0.6
0.6

0.6
0.6

0.6
0.6

6.9
6.9

8.3
8.3

7.8
7.8

0.1
0.1

0.1
0.1

0.3
0.3

2008 
2008 

2007 
2007 

2006 
2006 

2008 
2008 

2007 
2007 

2006 
2006 

2008 
2008 

2007 
2007 

2006 
2006 

2008 
2008 

2007 
2007 

2006 
2006 

2008 
2008 

2007 
2007 

2006 
2006 

2008 
2008 

2007 
2007 

2006 
2006 

(1) The Life Science segment profit for 2008 includes $28.8 million of goodwill and purchased intangibles impairment expense (see Note 5).
(1) The Life Science segment profit for 2008 includes $28.8 million of goodwill and purchased intangibles impairment expense (see Note 5).

(2) The Clinical Diagnostics segment profit for 2007 includes $7.7 million of in-process research and development expense purchased in the DiaMed  
(2) The Clinical Diagnostics segment profit for 2007 includes $7.7 million of in-process research and development expense purchased in the DiaMed  

acquisition (see Note 2).
acquisition (see Note 2).

(3) The Life Science segment profit for 2006 includes $3.8 million of in-process research and development expense purchased in the Ciphergen acquisition  
(3) The Life Science segment profit for 2006 includes $3.8 million of in-process research and development expense purchased in the Ciphergen acquisition  

(see Note 2).
(see Note 2).

Bio-Rad Laboratories  |  Annual Report 2008  :  59 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
noteS to conSoLidA ted finAnciAL St AtementS  (continued)

The difference between total segment allocated interest expense, depreciation and amortization, and capital 

expenditures and the corresponding consolidated amounts is attributable to our corporate headquarters. The  

following reconciles total segment profit to consolidated income before taxes and minority interests (in millions):

Total segment profit 

Other income (expense), net 

Foreign exchange losses 

Net corporate operating, interest and other

    Year Ended December 31,

  2008  

  2007  

  2006

$  153.7  

$  106.0  

$  115.9

(0.4) 

(7.6) 

19.8  

(2.6) 

29.0 

(1.1) 

income (expense) not allocated to segments 

(2.9) 

(2.4) 

(1.8)

Consolidated income before taxes 

  and minority interests  

$  142.8  

$  120.8  

$  142.0

The following reconciles total segment assets to consolidated total assets (in millions):

Total segment assets 

Cash and other current assets 

Net property, plant and equipment excluding

segment specific gross machinery and equipment 

Goodwill 

Other long-term assets 

Total assets 

 December 31,

2008  

2007 

$ 1,025.1  

$  1,006.7 

  388.5  

  363.3 

(6.6) 

  321.8  

  308.5  

(49.0)

  328.4

  322.2 

$ 2,037.3  

$  1,971.6 

The following presents sales to external customers by geographic area based primarily on the location of the use 

of the product or service (in millions):

Europe  

Pacific Rim  

United States  

Other (primarily Canada and Latin America) 

Total sales 

   Year Ended December 31,

2008  

2007  

2006

$  872.1  

$  671.2  

$  559.4 

  253.3  

  525.3  

113.7  

  209.9  

  498.1  

81.9  

  200.7 

  443.7 

70.1

$ 1,764.4  

$ 1,461.1   

$  1,273.9 

60  :  Bio-Rad Laboratories  |  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
The following presents long-lived assets by geographic area based upon the location of the asset (in millions):

Europe  

Pacific Rim 

United States  

Other (primarily Canada and Latin America) 

Total long-lived assets 

15. QUARTERLY FINANCIAL DATA (UNAUDITED)

   Year Ended December 31,

2008 

2007 

2006

$  543.4 

$  523.4 

$ 

88.1 

14.9 

12.9 

9.2 

  382.0 

  402.3 

  366.0 

3.0 

4.0 

3.1 

$  943.3 

$  942.6 

$  466.4 

Summarized quarterly financial data for 2008 and 2007 are as follows (in millions, except per share data):

2008   

Net sales 

Gross profit 

Net income (loss) 

Basic earnings (loss) per share 

Diluted earnings (loss) per share 

2007

Net sales 

Gross profit 

Net income 

Basic earnings per share 

Diluted earnings per share 

First  
Quarter 

Second  
Quarter 

Third  
Quarter 

Fourth
Quarter

$  422.2 

$  452.4 

$  441.8 

$  448.0 

  226.9 

  248.4 

  240.5 

  246.7 

26.5 

0.99 

0.96 

$ 

$ 

43.4 

1.61 

1.58 

$ 

$ 

27.8 

1.03 

1.01 

$ 

$ 

(8.2) 

(0.30)  

(0.30)  

$ 

$ 

$  322.5 

$  339.1 

$  339.7 

$  459.7 

  179.4 

  190.0 

  188.4 

  233.6 

27.0 

1.02 

0.99 

$ 

$ 

25.7 

0.96 

0.95 

$ 

$ 

28.0 

1.05 

1.03 

$ 

$ 

12.4 

0.46 

0.45 

$ 

$ 

Bio-Rad Laboratories  |  Annual Report 2008  :  61 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
RepoR t of independent RegiSteRed puBLic Accounting fiRm

Board of Directors and Stockholders

Bio-Rad Laboratories, Inc.

Hercules, California 

We have audited the accompanying consolidated balance sheets of Bio-Rad Laboratories, Inc. and subsidiaries 

(the “Company”) as of December 31, 2008 and 2007, and the related consolidated statements of income, stockholders’ 

equity, and cash flows for each of the three years in the period ended December 31, 2008. We also have audited 

the Company’s internal control over financial reporting as of December 31, 2008, based on criteria established in 

Internal Control — Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway 

Commission. The Company’s management is responsible for these financial statements, for maintaining effective 

internal control over financial reporting, and for its assessment of the effectiveness of internal control over financial 

reporting, included in the accompanying Management’s Report on Internal Control over Financial Reporting. Our 

responsibility is to express an opinion on these financial statements and an opinion on the Company’s internal 

control over financial reporting based on our audits.

We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board 

(United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about 

whether the financial statements are free of material misstatement and whether effective internal control over 

financial reporting was maintained in all material respects. Our audits of the financial statements included examining, 

on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the 

accounting principles used and significant estimates made by management, and evaluating the overall financial 

statement presentation. Our audit of internal control over financial reporting included obtaining an understanding 

of internal control over financial reporting, assessing the risk that a material weakness exists, and testing and 

evaluating the design and operating effectiveness of internal control based on the assessed risk. Our audits also 

included performing such other procedures as we considered necessary in the circumstances. We believe that  

our audits provide a reasonable basis for our opinions.

A company’s internal control over financial reporting is a process designed by, or under the supervision of, the 

company’s principal executive and principal financial officers, or persons performing similar functions, and 

effected by the company’s board of directors, management, and other personnel to provide reasonable assurance 

regarding the reliability of financial reporting and the preparation of financial statements for external purposes in 

accordance with generally accepted accounting principles. A company’s internal control over financial reporting 

includes those policies and procedures that (1) pertain to the maintenance of records that, in reasonable detail, 

accurately and fairly reflect the transactions and dispositions of the assets of the company; (2) provide reasonable 

assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance 

with generally accepted accounting principles, and that receipts and expenditures of the company are being made 

only in accordance with authorizations of management and directors of the company; and (3) provide reasonable 

assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company’s 

assets that could have a material effect on the financial statements.

62  :  Bio-Rad Laboratories  |  Annual Report 2008

Because of the inherent limitations of internal control over financial reporting, including the possibility of collusion 

or improper management override of controls, material misstatements due to error or fraud may not be prevented 

or detected on a timely basis. Also, projections of any evaluation of the effectiveness of the internal control over 

financial reporting to future periods are subject to the risk that the controls may become inadequate because of 

changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate. 

In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the 

financial position of Bio-Rad Laboratories, Inc. and subsidiaries as of December 31, 2008 and 2007, and the 

results of their operations and their cash flows for each of the three years in the period ended December 31, 2008,  

in conformity with accounting principles generally accepted in the United States of America. Also, in our opinion, 

the Company maintained, in all material respects, effective internal control over financial reporting as of  

December 31, 2008, based on the criteria established in Internal Control—Integrated Framework issued by the 

Committee of Sponsoring Organizations of the Treadway Commission.

As discussed in Note 7 of the Notes to the Consolidated Financial Statements, in 2007 the Company adopted a 

new interpretation of accounting standards for uncertainty in income taxes.

San Francisco, California 

February 25, 2009 

Bio-Rad Laboratories  |  Annual Report 2008  :  63 

mAnAgement’S diScuSSion And AnAL ySiS

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS 

This discussion should be read in conjunction with the information contained in our consolidated financial statements 

and the accompanying notes which are an integral part of the statements.

Other than statements of historical fact, statements made in this Annual Report include forward-looking statements, 

such as statements with respect to our future financial performance, operating results, plans and objectives that 

involve risk and uncertainties. Forward-looking statements generally can be identified by the use of forward-looking 

terminology such as, “believe”, “expect,” “may,” “will,” “intend,” “estimate,” “continue,” or similar expressions or 

the negative of those terms or expressions. Such statements involve risks and uncertainties, which could cause 

actual results to vary materially from those expressed in or indicated by the forward-looking statements. We have 

based these forward-looking statements on our current expectations and projections about future events. However, 

actual results may differ materially from those currently anticipated depending on a variety of risk factors including 

among other things: changes in general domestic and worldwide economic conditions; our ability to successfully 

develop and market new products; our reliance on and access to necessary intellectual property; our ability to  

successfully integrate any acquired business; our substantial leverage and ability to service our debt; competition 

in and government regulation of the industries in which we operate; and the monetary policies of various countries. 

We caution you not to place undue reliance on forward-looking statements, which reflect an analysis only and speak 

only as of the date hereof. We undertake no obligation to publicly update or revise any forward-looking statements, 

whether as a result of new information, future events, or otherwise except as required by Federal Securities law.

Overview

Bio-Rad is a multinational manufacturer and worldwide distributor of our own life science research and clinical 

diagnostics products. Our business is organized into two primary segments, Life Science and Clinical Diagnostics, 

with the mission to provide scientists with specialized tools needed for biological research and clinical diagnostics. 

We sell more than 8,000 products and services to a diverse client base comprised of scientific research, healthcare, 

education and government customers worldwide. We manufacture and supply our customers with a range of 

reagents, apparatus and equipment to separate complex chemical and biological materials and to identify, analyze 

and purify components. Because our customers require replication of results in manufacturing processes, research 

experiments and diagnostic tests, much of our revenues are recurring. Approximately 30% of our 2008 consolidated 

net sales are from the United States and approximately 70% are international sales, largely denominated in local 

currency with the majority of these sales in Euros, Yen and British Sterling. As a result, our consolidated net sales 

expressed in dollars benefit when the U.S. dollar weakens and suffer when the U.S. dollar strengthens in relation 

to other currencies. Currency fluctuations benefited our consolidated net sales expressed in U.S. dollars in 2008, 

2007 and 2006. The market for reagents and apparatus remains good while growth rates have slowed due to both 

public and private grant funding being more measured. The market for large capital equipment has slowed, as 

many pharmaceutical and biotechnology customers delayed or reduced their capital spending. Bio-Rad is generally 

less impacted by trends in capital spending as lower priced reagents and apparatus comprise more than 70% of 

product sales.

64  :  Bio-Rad Laboratories  |  Annual Report 2008

The following shows gross profit and expense items as a percentage of net sales:

Net sales 

  Cost of goods sold 

Gross profit 

Selling, general and administrative expense  

Product research and development expense,  

  excluding in-process research and development 

Net income 

 Year Ended December 31, 

2008    

  100.0% 

45.4    

54.6    

33.5    

9.0    

5.1    

2007    

100.0% 

45.8    

54.2    

34.8    

9.6    

6.4    

2006

100.0%

44.1

55.9

34.5

9.7

8.1

We intend that the discussions of critical accounting policies and estimates and recent accounting pronouncements 

that follow will assist you in understanding how such principles, estimates and pronouncements affect our financial 

condition and results of operations as well as significant factors that caused changes in our financial condition and 

results of operations for the years ended December 31, 2008 and 2007.

CRITICAL ACCOUNTING POLICIES AND ESTIMATES

The accompanying discussion and analysis of our financial condition and results of operations are based upon our 

consolidated financial statements, which have been prepared in accordance with generally accepted accounting 

principles in the United States of America (GAAP). The preparation of financial statements in conformity with GAAP 

requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities and 

contingencies as of the date of the financial statements and reported amounts of revenues and expenses during the 

reporting periods. We evaluate our estimates on an on-going basis. We base our estimates on historical experience 

and on other assumptions that are believed to be reasonable under the circumstances, the results of which form  

the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from  

other sources. However, future events may cause us to change our assumptions and estimates which may require 

routine adjustment. Actual results could differ from these estimates. We have determined that for the periods 

reported in this Annual Report the following accounting policies and estimates are critical in understanding our financial 

condition and results of operations.

Accounting for Income Taxes

As part of the process of preparing consolidated financial statements, management is required to estimate our 

income taxes in each of the jurisdictions in which we operate. This process involves estimating our current tax  

exposure together with assessing temporary differences resulting from differing treatment of items for tax and 

accounting purposes. These differences result in deferred tax assets and liabilities, which are included within our 

consolidated balance sheet. Management then assesses the likelihood that the deferred tax assets will be recovered 

from future taxable income and to the extent management believes that recovery is not likely, a valuation allowance 

must be established. To the extent management establishes a valuation allowance or increases this allowance in  

a period, an increase to expense within the provision for income taxes in the statement of income may result.

Bio-Rad Laboratories  |  Annual Report 2008  :  65 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
mAnAgement’S diScuSSion And AnAL ySiS  (continued)

Significant management judgment is required in determining the provision for income taxes, deferred tax assets and 

liabilities and any valuation allowance recorded in connection with the deferred tax assets. We have recorded a valuation 

allowance of $40.7 million and $31.1 million as of December 31, 2008 and 2007 respectively, due to uncertainties 

related to our ability to utilize some of the deferred tax assets, primarily consisting of certain foreign net operating 

losses carried forward, before they expire. The valuation allowance is based on management’s current estimates of 

taxable income for the jurisdictions in which we operate and the period over which the deferred tax assets will be 

recoverable. In the event that actual results differ from these estimates, or these estimates are adjusted in future periods, 

an additional valuation allowance may need to be established which would increase the tax provision, lowering 

income and impacting our financial position. Should realization of these deferred assets previously reserved occur, 

the provision for income tax would decrease, raising income and positively impacting Bio-Rad’s financial position.

Valuation of Long-lived and Intangible Assets and Goodwill

We assess the impairment of identifiable intangibles, long-lived assets and goodwill annually in the fourth quarter 

or whenever events or changes in circumstances indicate that the carrying value may not be recoverable. Projected 

future operating results and cash flows of the reporting units’ asset or asset group are used to establish the fair 

value used in evaluating the carrying value of long-lived and intangible assets and goodwill. Factors that we consider 

important that could trigger an impairment review include the following:

•  significant under-performance relative to expected, historical or projected future operating results;

•  significant changes in the manner of use of the long-lived assets, intangible assets or the strategy for  

our overall business; and

•  significant negative industry or economic trends.

When management determines that the carrying value of intangibles or long-lived assets may not be recoverable 

based upon the existence of one or more of the above indicators of impairment, we test for any impairment based 

on a projected undiscounted cash flow method. Goodwill is tested for impairment based on a projected discounted 

cash flow method. Projections are inherently uncertain and accordingly, actual future cash flows may differ materially 

from projected cash flows. The discounted cash value projected for goodwill may be different from the fair value 

that would result from an actual transaction between a willing buyer and a willing seller. Such analyses are particularly 

sensitive to changes in discount rates. Changes to these rates might result in material changes in the valuation and 

determination of the recoverability of goodwill. For example, an increase in the interest rate used to discount cash 

flows will decrease the discounted cash value.

In 2008, our review indicated a $28.8 million impairment loss: $1.6 million related to the developed technology 

intangible assets of certain product lines that were acquired in 2006 and $27.2 million related to goodwill from 

a 1999 acquisition. The goodwill impairment was caused primarily by the continuing decline in the BSE (bovine 

spongiform encephalopathy) product line. There were no impairments taken in 2007 and 2006.

Valuation of Inventories

We value inventory at the lower of the actual cost to purchase and/or manufacture the inventory, or the current 

estimated market value of the inventory. We review inventory quantities on hand and record a provision for excess 

and obsolete inventory based primarily on an estimated forecast of product demand and production requirements 

for the next twelve months on a quarterly basis or, if warranted by the circumstances, more frequently. In addition, 

our industry is characterized by technological change, frequent new product development and product obsolescence 
that could result in an increase in the amount of obsolete inventory quantities on hand. Our estimates of  future 
product demand may prove to be inaccurate, in which case we may have understated or overstated the valuation

66  :  Bio-Rad Laboratories  |  Annual Report 2008

allowance required for excess and obsolete inventory. In the future, if inventory is determined to be overvalued, we 

would be required to recognize such costs in our cost of goods sold at the time of such determination by initiating 

or increasing our inventory valuation allowance. Likewise, if the inventory valuation allowance is determined to be no 

longer required, we may have over-reported cost of goods sold in previous periods and would be required to recognize 

such additional operating income at the time of sale until the inventory allowance is depleted. In no case is 

inventory valued at an amount greater than cost. Therefore, although we make efforts to ensure the accuracy of 

our forecasts of future product demand, any significant unanticipated changes in demand, technological developments 

or regulations could have a significant impact on the value of our inventory and reported results of operations.

Valuation of Investments

We regularly review our investments for factors that may indicate that a decline in the fair value of an investment 

below its cost is other than temporary. Some factors considered in evaluating whether or not a decline in fair value 

is other-than-temporary include our ability and intent to retain the investment for a period of time sufficient to allow 

for a recovery in value, the duration and extent to which the fair value has been less than cost and the financial 

condition and prospects of the issuer. Such reviews are inherently uncertain in that the value of the investment may 

not fully recover or may decline further in future periods resulting in realized losses.

Warranty Reserves

We warrant certain equipment against defects in design, materials and workmanship, generally for a period of one 

year. Upon delivery and on acceptance of that equipment, we establish, as part of cost of goods sold, a provision 

for the expected costs of such warranty based on historical experience, specific warranty terms and customer 

feedback.  A review is performed on a quarterly basis to assess the adequacy of our warranty reserve and it is 

adjusted if necessary. The warranty percentage and accrual are based on actual experience and expected future 

costs to be incurred. Should realized costs be higher than expected costs, cost of goods sold would be lower in 

the period of estimation and higher when realized.

Allowance for Doubtful Accounts

We maintain an allowance for doubtful accounts for estimated losses resulting from the inability of our customers to 

make required payments. The amount of the allowance is determined by analyzing known uncollectible accounts, 

the age of our receivables, economic conditions in the customers’ country or industry, historical losses and our 

customers’ general credit-worthiness. Amounts later determined and specifically identified to be uncollectible are 

charged or written off against this reserve. This valuation allowance is reviewed on a quarterly basis to determine 

whether an increase or decrease is warranted. Uncertainty in the current economic environment, if prolonged, 

could result in greater amounts becoming uncollectible in the future. Should the estimates of losses be higher than 

the actual uncollectible accounts, we would report lower profitability when the estimates are made and higher 

profitability when the receivable is collected.

Litigation Reserves

We estimate amounts for claims that are probable and can be reasonably estimated are recorded as liabilities in 

our consolidated balance sheets. The likelihood of a material change in these estimated reserves is dependent on 

the possible outcome of settlement negotiations, regulatory or judicial review and the development of facts and 

circumstances in extended litigation which could change claims or assessments when both the amount and range 

of loss on some outstanding litigation is uncertain. We disclose in the footnotes of the financial statements when 

we are unable to make a reasonable estimate of the liability that could result from unfavorable outcomes in litigation. 

As events occur, we will assess the potential liability related to our pending litigation and revise our estimates. 

Such revisions could materially impact our results of operations.

Bio-Rad Laboratories  |  Annual Report 2008  :  67 

mAnAgement’S diScuSSion And AnAL ySiS  (continued)

CORPORATE RESULTS—SALES, MARGINS AND EXPENSES

Our net sales increased by 20.8% in 2008 to $1,764.4 million as compared to 2007. This includes sales related to 

the fourth quarter 2007 acquisition of DiaMed Holding AG (DiaMed). The impact of foreign exchange translation 

aided sales growth by approximately 3%. The incremental sales from the additional nine months in 2008 attributable 

to DiaMed accounted for approximately 13% of our annual growth. 

The Life Science segment achieved sales growth of 4.6% in 2008 as compared to 2007 aided by the impact of 

foreign exchange translation of 3.2%. The decline in sales of BSE (bovine spongiform encephalopathy) products 

continued in 2008, as both product prices eroded among multiple suppliers and government mandated tests 

declined. Excluding the impact of the BSE product line, this segment grew by 6.6%. Increased sales were the 

result of growth in multianalyte detection, protein interaction, DNA amplification and laboratory chromatography 

product lines. Sales in the United States, emerging markets and Asia Pacific (excluding Japan), were the drivers  

of increased sales growth. 

The Clinical Diagnostics segment achieved sales growth of 33.0% in 2008 as compared to 2007 which includes 

sales growth from our acquisition of DiaMed. The incremental sales from the additional nine months of DiaMed 

operations provided 22.8% of our Clinical Diagnostics sales growth. The impact of foreign exchange on Clinical 

Diagnostics segment sales growth added approximately 2.9% to total segment sales. The Clinical Diagnostics 

segment experienced growth across a wide range of its product offerings with the BioPlex 2200 system, quality 

controls and clinical microbiology having the strongest growth. Geographically, the drivers of sales growth excluding 

the DiaMed acquisition were in the United States, Europe and Asia Pacific (excluding Japan).

Our net sales increased by 14.7% in 2007 to $1,461.0 million as compared to 2006. This includes $62.0 million 

of sales in the fourth quarter related to the acquisition of DiaMed completed on October 1, 2007. Excluding these 

sales, sales growth was 9.8%. The impact of foreign exchange translation aided sales growth by approximately 4.6%.

The Life Science segment achieved sales growth of 6.9% in 2007 as compared to 2006 aided by the impact of 

foreign exchange translation of 4.2%. Excluding the impact of the food science product line, this segment grew 

by 11.0%. Increased sales were the result of growth in multianalyte detection, protein interaction and process 

chromatography product lines. Sales in the United States, emerging markets and Asia Pacific (excluding Japan), 

were the drivers of increased sales growth. The decline in sales of BSE products continued in 2007, as multiple 

test providers lowered product prices and government mandated tests declined.

The Clinical Diagnostics segment achieved sales growth of 21.5% in 2007 as compared to 2006 which includes 

sales growth that resulted from our acquisition of DiaMed. We include DiaMed’s results in this reporting segment 

because DiaMed’s customers, technology, distribution channels and economics (post integration) are all similar 

to our Clinical Diagnostics segment. DiaMed’s sales provided 9.1% of our Clinical Diagnostics sales growth. The 

impact of foreign exchange on Clinical Diagnostics segment sales growth added approximately 5.1% to total 

segment sales. The Clinical Diagnostics segment experienced growth across a wide range of its product offerings. 

Geographically, the drivers of sales growth excluding the DiaMed acquisition were in the United States and Asia 

Pacific (excluding Japan).

68  :  Bio-Rad Laboratories  |  Annual Report 2008

The 2008 consolidated gross margin of 54.6% represents an increase of 0.4% from 2007. Life Science segment 

gross margins increased by 2.0% to 54.1% as a result of decreasing factory costs in some overhead areas, 

improved production planning, reduced quality defects and improved sales mix. The Clinical Diagnostics segment 

gross margins decreased by 0.8% in 2008 as compared to 2007 as a result of including an additional nine months 

of DiaMed operations. The DiaMed gross margins include the amortization of manufacturing related purchased 

intangibles and the effect of higher inventory values after work-in-process inventory values were increased in 

compliance with purchase accounting requirements.

The 2007 consolidated gross margin of 54.2% represents a decline of 1.7% from 2006. Life Science segment 

gross margins declined by less than 1% from the underabsorption of factory costs due to lower than planned 

activity in the first half of 2007, rising costs throughout the year and an unfavorable sales mix. The Clinical Diagnostics 

segment gross margins declined by 2.4% from 2006, as the result of the DiaMed acquisition and the inclusion of 

$11.7 million in 2006 of back royalties with no related costs.

Consolidated selling, general and administrative expense (SG&A) for 2008 was 33.5% of net sales compared 

to 34.8% in 2007. The decline from the prior year is mainly attributable to the inclusion of DiaMed which has an 

overall lower SG&A margin compared to its total sales. Growth in absolute SG&A spending was proportional to 

sales with Life Science segment’s SG&A growing just faster than sales growth while Clinical Diagnostics grew at a 

slightly lower rate, excluding the impact of DiaMed. Approximately half of the increase in SG&A is related to personnel 

costs including compensation and travel. The remaining increases are attributable to agent commissions, technology 

infrastructure cost, professional services and provision for bad debts.

Consolidated SG&A was 34.8% of net sales for 2007 compared to 34.5% in 2006. Increased spending on a currency 

neutral basis represents approximately $32 million of SG&A growth for Bio-Rad in 2007, excluding DiaMed.  

Two-thirds of the increased spending is related to the Clinical Diagnostics segment with the remainder associated 

with the Life Science segment. Personnel and related costs account for approximately 60% of total SG&A expense. 

Other increasing areas of costs are travel, marketing and technology costs.

Product research and development expense in 2008 declined to 9.0% of net sales as compared to 9.6% of net 

sales in 2006. Areas of development for the Life Science segment were amplification, proteomics, protein function, 

food safety and process chromatography. Clinical Diagnostics segment research and development were focused 

on additional assays for the BioPlex 2200 testing platform as well as investments in automation for the DiaMed line 

of blood typing instruments and reagents, product line extensions in diabetes, infectious disease, quality control and 

software offerings. In absolute dollars, the increase in R&D was almost exclusively in the Clinical Diagnostics segment.

Product research and development expense in 2007 declined to 9.6% of net sales compared to 9.7% of net sales 

in 2006 excluding the purchased in-process research and development associated with acquisitions made in 

2007 and 2006. Areas of development for the Life Science segment were amplification, proteomics and process 

chromatography. Clinical Diagnostics segment research and development were focused on additional assays for 

the BioPlex 2200 testing platform as well as enhancements to existing clinical microbiology, autoimmune, diabetes 

monitoring, blood virus and quality control products. In absolute dollars, the increased spending was proportionately 

much higher in the Clinical Diagnostics segment than in the Life Science segment.

Bio-Rad Laboratories  |  Annual Report 2008  :  69 

mAnAgement’S diScuSSion And AnAL ySiS  (continued)

CORPORATE RESULTS—NON-OPERATING  

Interest expense increased by approximately $0.5 million in 2008 as compared to 2007. The increase reflects higher 

average borrowings on local lines of credit and increased interest on capital leases. Our principal debt obligations 

are the 2003 and 2004 Senior Subordinated Notes totaling $425.0 million which carry fixed rates of interest of 

7.5% and 6.125%, and are not due until August 2013 and December 2014.

Interest expense declined by approximately $0.4 million in 2007 compared to 2006. The decline reflects lower 

average borrowings on local lines of credit. The majority of interest costs are associated with the $425.0 million  

in Senior Subordinated Notes.

Foreign exchange losses for 2008, 2007 and 2006 were $7.6 million, $2.6 million and $1.1 million, respectively. The 

largest component in the current year loss is a fourth quarter loss of approximately $5.2 million. The loss reflects 

a number of unhedged European based intercompany loans denominated in Euros, GBP and Swiss Francs which 

arose as part of our acquisitions in December 2008. The significant volatility in December resulted in an approximate 

$3.0 million non-cash loss on these accounts. Additionally, we recorded a loss of $1.6 million on unhedged inter-

company payables for our Brazilian subsidiaries, which we have not historically hedged due to the high cost. In the 

fourth quarter of 2007 there was a loss of approximately $2.5 million on the exchange of Euros for Swiss Francs 

related to our purchase of DiaMed. All years are affected by the economic hedging program we employ to hedge 

our intercompany receivables and payables.

Other income and expense for 2008 is comprised of interest and investment income of $10.6 million on cash and 

short-term investments. We expect interest and investment income to decline in 2009 as returns on short-term 

fixed income investment have declined significantly in the current economic environment. During the year we 

impaired $9.6 million of marketable equity securities, marketable fixed income securities and long-term investees. 

In each case, the market value of these securities had declined so significantly at December 31, 2008 that their 

recovery in the foreseeable future could not be anticipated. Additional write downs could be possible should 

markets continue to function with only limited liquidity and some regulatory forbearance is not offered.

Other income and expense for the year 2007 is principally comprised of $21.5 million of investment income for 

interest on cash, cash equivalents and short-term investments. Our investment income declined faster as the 

amount invested declined in the fourth quarter when we used approximately $400 million to purchase DiaMed. 

Other factors affecting comparability between years is the 2007 impairment of two investments totaling $3.6 million. 

Conversely in 2006, we had other income of $4.7 million relating to a facilitation fee received and a gain on the 

tendering of our shares in the merger between Accent Semiconductor Technology Inc. and Nanometrics Inc.

Bio-Rad’s consolidated effective tax rate was 31%, 22%, and 27% in 2008, 2007, and 2006, respectively. The 

2008, 2007, and 2006 effective tax rates reflect tax rate benefits of 4%, 5% and 3%, respectively for non-taxable 

dividend income, and 9%, 8%, and 2%, respectively for tax credits. The 2008, 2007, and 2006 effective tax rates 

also reflect benefits in the difference between U.S. and foreign taxes of 4%, 2%, and 1%, respectively. The 2008 

tax rate reflects a rate detriment of 7% with respect to goodwill impairments. The 2007 tax rate reflects a rate 

benefit of 3% for the removal of a valuation allowance related to Canadian deferred tax assets.

Our effective tax rate may be impacted in the future, either favorably or unfavorably, by many factors including 

but not limited to fluctuations in statutory tax rates and changes in tax laws or regulations, which could cause our 

estimate of taxes to change.

70  :  Bio-Rad Laboratories  |  Annual Report 2008

LIQUIDITY AND CAPITAL RESOURCES

Bio-Rad operates and conducts business globally, primarily through subsidiary companies established in the 

markets in which we trade. Goods are manufactured in a small number of locations, and intermediate or finished 

products are then shipped for completion and/or distribution to facilities around the globe. Our product mix is 

diversified, and certain products compete largely on product efficacy, while others compete on price. Gross 

margins are generally sufficient to exceed normal operating costs. Funding for research and development of 

new products as well as routine outflows of capital expenditure, and tax expense are covered by cash flow from 

operations. We currently operate with an adequate level of interest coverage and our current market capitalization 

is high relative to our current level of debt. In addition to the positive cash flow from operating activities, additional 

liquidity is readily available via the sale of short-term investments and our revolving credit facility.

Recent financial and economic developments may adversely affect our future results of operations. Demand for our 

products and services could change more dramatically than in previous years based on activity and support levels 

from government, universities, hospitals and private industry including diagnostic laboratories. A slowdown in the 

global economy including the United States has caused many governments to announce stimulus packages that 

often promote support for healthcare and research. These efforts, should they materialize, could offset other declines 

to our business. To date we are unable to conclude how dramatically the global economic recession will impact us.

At December 31, 2008, we had available $243.5 million in cash, cash equivalents and short-term investments, 

and $20.3 million under international lines of credit. Under the $200.0 million restated and amended Revolving 

Credit Facility, we have $192.3 million available with $7.7 million reserved for standby letters of credit issued by 

our banks to guarantee our obligations to certain insurance companies. Management believes that this availability, 

together with cash flow from operations, will be adequate to meet our current objectives for operations, research 

and development, capital additions for plant, equipment and systems and to make the tender offer to the minority 

shareholders of DiaMed Holding as outlined in the DiaMed purchase and sale agreement.

Recent deteriorations in credit markets along with the financial service industry experiencing upheavals characterized 

by bankruptcy, foreclosures, collapse and government intervention could impact both our ability and our customer’s 

ability to access the necessary capital for acquisition, equipment and technology modernization and the financing 

of inventory and receivables. Without this crucial intermediary function manufacturers and end users may have to 

renegotiate sharing additional costs, reduce activity levels or seek other business partners.

Cash Flow from Operations

Net cash provided by operations was $191.4 million, $191.6 million, and $118.2 million in 2008, 2007, and 2006, 

respectively. The small net change between 2008 and 2007 is the result of an increase in net cash collections 

reduced by supplier and employee payments, offset by income tax payments and lower investment income and 

other miscellaneous operating receipts.

During 2008 the increase in inventory compared to 2007 is concentrated in the Life Science segment and the 

quality control product line of the Clinical Diagnostics segment. Quality control products are characterized by long 

lead times and market opportunities going forward appear stable. Life Science segment inventories grew to meet 

anticipated sales that were delayed or cancelled as economic activities declined in the fourth quarter. First quarter 

2009 cash flows are historically the lowest as annual payments for royalties and bonuses are due in this period.

Bio-Rad Laboratories  |  Annual Report 2008  :  71 

mAnAgement’S diScuSSion And AnAL ySiS  (continued)

During 2007, the moderation of growth in inventory and accounts receivable compared to 2006 contributed to the overall 

improvement in cash flow from operations. Additional cash flows were also generated by the acquisition of DiaMed.

Management regularly reviews the allowance for uncollectible receivables and believes net accounts receivable 

are fully realizable. Management routinely reviews inventory for the impact of obsolescence and changes in market 

prices caused by the introduction of new products, technologies and in government reimbursement policies.

Cash Flow from Investing Activities

Net cash used in investing activities, including capital expenditures, was $146.1 million for the year 2008. During 

the year we paid cash for the acquisition of additional DiaMed minority shares and two distributors. In 2009, we 

intend to offer to buy the outstanding shares of the minority shareholders of DiaMed Holding. We estimate this 

offer will use approximately another $38 million in cash. We may also purchase some additional distributors.

Capital expenditures in 2008 totaled $84.8 million, compared to $60.6 million and $53.0 million in 2007 and 2006, 

respectively. Net capital expenditures for 2008 reflect investment in improvements to new information technology 

systems, new e-commerce and content management technology for our website and the expansion of manufacturing 

capabilities as well as refurbishing some administrative space. Spending on reagent rental instruments was  

$24.9 million. We place reagent rental instruments with our Clinical Diagnostics customers for use with our clinical 

reagents. We continued in 2008 to invest in business systems to modernize and standardize distribution capabilities 

and enhance data communication. Other ongoing expenditures are for the replacement and improvement of 

production equipment and facilities to meet the necessary Good Manufacturing Practices (GMP) mandated by the 

Food and Drug Administration (FDA) for the Clinical Diagnostics segment and to meet the requirements of European 

and other regulatory bodies as well as many customers in our Life Science segment.

Cash Flow from Financing Activities

Net cash flow provided by financing activities was $6.3 million for 2008 and principally reflects the cash flow for 

the exercise of stock options and receipts from the Employee Stock Purchase Plan transactions. Payments on 

long-term debt represent the reduction of acquired DiaMed debt. We have previously borrowed $200 million at 

6.125% due 2014 and $225 million at 7.5% due 2013. This has provided us with capital at a fixed rate for the next 

five and four years, respectively. We routinely meet and discuss potential acquisitions with specific companies, 

principals or their agents. Should we identify any significant potential acquisitions it could require an increase in 

our total indebtedness.

Our $200.0 million revolving credit facility is secured by substantially all of our personal property assets and the 

assets of our domestic subsidiaries and 65% of the capital stock of certain foreign subsidiaries, and is guaranteed 

by all of our existing and future domestic subsidiaries (other than immaterial domestic subsidiaries as defined for 

purposes of the new credit facility).

The Board of Directors has authorized us to repurchase up to $18 million of Bio-Rad’s common stock over an 

indefinite period of time of which $3.3 million is remaining. Our credit agreements restrict our ability to repurchase 

our own stock. There were no share repurchases made during 2008 or 2007.

72  :  Bio-Rad Laboratories  |  Annual Report 2008

CONTRACTUAL OBLIGATIONS

The following summarizes certain of our contractual obligations as of December 31, 2008 and the effect such 

obligations are expected to have on our cash flows in future periods (in millions):

Contractual Obligations  

Long-term debt, including  

  current portion (1)  

Interest payments  

Operating lease obligations (2) 

Purchase obligations (3)  

Long-term liabilities (4)  

Total 

Less than 
One Year 

1-3 
Years 

3-5 
Years 

More than
5 Years

453.1 

152.3 

108.1 

22.7 

40.7 

7.2 

 29.1 

31.7 

20.9 

— 

10.9 

58.3 

48.9 

1.8 

9.0 

225.2 

  209.8 

52.6 

19.5 

— 

7.9 

12.3 

8.0 

—

23.8 

(1) These amounts represent expected cash payments, include capital lease obligations and are included in our Consolidated Balance Sheets. See Note 6 of 

the Consolidated Financial Statements for additional information about our debt.

(2) Operating lease obligations are described in Note 12 of the Consolidated Financial Statements.

(3) Purchase obligations include agreements to purchase goods or services that are enforceable and legally binding to Bio-Rad and that specify all significant 

terms. Purchase obligations exclude agreements that are cancelable without penalty.

(4) Excluded from this table is our liability for income tax payable, including uncertain tax positions, in the amount of $19.4 million. We are not able to reason-
ably estimate the timing of future cash flows of these tax liabilities, therefore, our income tax obligations are excluded from the table above. See Note 7 of 
the Consolidated Financial Statements.

FINANCIAL RISK MANAGEMENT

The main goal of Bio-Rad’s financial risk management program is to reduce the variance in expected cash flows 

arising from unexpected foreign exchange rate and interest rate changes. Financial exposures are managed through 

operational means and by using various financial instruments, including cash and liquid resources, borrowings, 

spot foreign exchange contracts and derivatives. The derivative instruments used are principally comprised of 

forward foreign exchange contracts. No derivative financial instruments are entered into for the purpose of trading 

or speculation. Company policy requires that all derivative positions are undertaken to manage the risks arising 

from underlying business activities. These derivative transactions do not qualify for hedge accounting treatment 

under SFAS 133, Accounting for Derivative Instruments and Hedging Activities. Derivative instruments used in 

these transactions are valued at fair value and changes in fair value are included in reported earnings.

Foreign Exchange Risk

We operate and conduct business in many countries and are exposed to movements in foreign currency exchange 

rates. We face transactional currency exposures that arise when we enter into transactions denominated in currencies 

other than U.S. dollars. Additionally, our consolidated net equity is impacted by the conversion of the net assets of 

our international subsidiaries for which the functional currency is not the U.S. dollar.

Foreign currency exposures are managed on a centralized basis. This allows for the netting of natural offsets and 

lowers transaction costs and net exposures. Where possible, we seek to manage our foreign exchange risk in part 

through operational means, including matching same-currency revenues to same currency costs, and same-currency 

assets to same-currency liabilities. Moreover, weakening in one currency can often be offset by strengthening in 

another currency. Foreign exchange risk is also managed through the use of forward foreign exchange contracts.

Bio-Rad Laboratories  |  Annual Report 2008  :  73 

 
 
 
 
 
 
mAnAgement’S diScuSSion And AnAL ySiS  (continued)

Positions are primarily in Euro, Swiss Franc, British Sterling and Japanese Yen. The majority of forward contracts 

are for periods of 90 days or less. We record the change in value of our foreign currency receivables  

and payables as a foreign exchange (gain) loss on our Consolidated Statements of Income along with the change 

in fair market value of the forward exchange contract used as an economic hedge of those assets or liabilities.

Our forward contract holdings at year-end were analyzed to determine their sensitivity to fluctuations in foreign 

currency exchange rates. All other variables were held constant. Market risk associated with derivative holdings 

is the potential change in fair value of derivative positions arising from an adverse movement in foreign exchange 

rates. A decline of 10% on quoted foreign exchange rates would result in an approximate net-present-value loss  

of $18 million on our derivative position. This impact of a change in exchange rates excludes the offset derived 

from the change in value of the underlying assets and liabilities, which could reduce the adverse effect significantly.

Interest Rate Risk of Debt Instruments

Bio-Rad centrally manages the short-term cash surpluses and shortfalls of its subsidiaries. Our holdings of variable 

rate debt instruments at year-end were analyzed to determine their sensitivity to movements in interest rates. Due 

to the relatively small amount of short-term variable rate debt we have outstanding, there would not be a material 

impact to earnings or cash flows if interest rates moved adversely by 10%. Our long-term debt consists primarily 

of fixed-rate instruments, and is thus insulated from interest rate changes. As of December 31, 2008 the overall 

interest rate risk associated with our debt was not significant.

RECENT FINANCIAL ACCOUNTING STANDARDS

In June 2008, the Financial Accounting Standards Board (FASB) issued FASB Staff Position (FSP) No. Emerging 

Issues Task Force (EITF) 03-6-1, Determining Whether Instruments Granted in Share-Based Payment Transactions 

Are Participating Securities. FSP No. EITF 03-6-1 concluded that unvested share-based payment awards that 

contain nonforfeitable rights to dividends or dividend equivalents (whether paid or unpaid) are participating securities 

and shall be included in the computation of basic earnings per share (EPS) pursuant to the two-class method. This 

FSP becomes effective for us on January 1, 2009. Early adoption of the FSP is not permitted; however, it will apply 

retrospectively to EPS data for all periods presented in the financial statements or in financial data. We do not currently 

expect that this FSP will have a material impact on our EPS data in fiscal year 2009 or on EPS for any prior periods.

In May 2008, the FASB issued SFAS 162, The Hierarchy of Generally Accepted Accounting Principles.  

SFAS 162 identifies the sources of accounting principles and the framework for selecting principles to be used 

in the preparation and presentation of financial statements in accordance with generally accepted accounting 

principles in the United States of America. The adoption of SFAS 162 will not have an effect on our consolidated 

financial statements.

In March 2008, the FASB issued SFAS 161, Disclosures about Derivative Instruments and Hedging Activities— 

an amendment of SFAS 133. SFAS 161 seeks to improve financial reporting for derivative instruments and hedging 

activities by requiring enhanced disclosures regarding the impact on financial position, financial performance, and 

cash flows. SFAS 161 is effective for us on January 1, 2009. Since SFAS 161 requires only additional disclosures 

concerning derivatives and hedging activities, the adoption of SFAS 161 will not affect our financial condition, 

results of operations or cash flows.

74  :  Bio-Rad Laboratories  |  Annual Report 2008

As amended in February 2008 by FSP No. FAS 157-2, Effective Date of FASB Statement No. 157, SFAS 157, Fair 

Value Measurements, defines fair value, establishes a framework for measuring fair value and expands disclosures 

about fair value measurements. FSP FAS 157-2 defers the effective date of SFAS 157 for all nonfinancial assets 

and liabilities, except those items recognized or disclosed at fair value on an annual or more frequently recurring 

basis, until January 1, 2009. As such, we partially adopted the provisions of SFAS 157 effective January 1, 2008. 

We expect to adopt the remaining provisions of SFAS 157 beginning in 2009. We expect the adoption of SFAS 157 

to impact the way in which we calculate fair value for our annual impairment review of goodwill and non-amortizable 

intangible assets, and when conditions exist that require us to calculate the fair value of long-lived assets; however, 

we do not expect this adoption to have a material impact on our consolidated financial statements.

In December 2007, the FASB issued SFAS 141R, Business Combinations. SFAS 141R continues to require the 

purchase method of accounting to be applied to all business combinations, but it significantly changes the 

accounting for certain aspects of business combinations. Under SFAS 141R, an acquiring entity will be required 

to recognize all the assets acquired and liabilities assumed in a transaction at the acquisition-date fair value with 

limited exceptions. SFAS 141R will change the accounting treatment for certain specific acquisition related items 

including: (1) expensing acquisition related costs as incurred; (2) valuing noncontrolling interests at fair value at 

the acquisition date; and (3) expensing restructuring costs associated with an acquired business. SFAS 141R also 

includes a substantial number of new disclosure requirements. SFAS 141R is to be applied prospectively to business 

combinations for which the acquisition date is on or after January 1, 2009. We expect SFAS 141R will have an 

impact on our accounting for future business combinations once adopted but the effect is dependent upon the 

acquisitions that are made in the future.

In December 2007, SFAS 160, Noncontrolling Interests in Consolidated Financial Statements, was issued.  

SFAS 160 establishes new accounting and reporting standards for the noncontrolling interest in a subsidiary  

and for the deconsolidation of a subsidiary. It clarifies that a noncontrolling interest in a subsidiary (minority interest)  

is an ownership interest in the consolidated entity that should be reported as equity in the consolidated financial 

statements and separate from the parent company’s equity. Among other requirements, this statement requires 

consolidated net income to be reported at amounts that include the amounts attributable to both the parent  

and the noncontrolling interest. It also requires disclosure, on the face of the consolidated statement of income,  

of the amounts of consolidated net income attributable to the parent and to the noncontrolling income interest. 

This statement is effective for us on January 1, 2009. When implemented, prior periods will be recast for  

the changes required by SFAS 160. The adoption of this standard will not have a material impact on our  

consolidated financial statements.

Bio-Rad Laboratories  |  Annual Report 2008  :  75 

coRpoRA te infoRmA tion

DIR EC TORS

David Schwartz
chairman of the Board

James J. Bennett
director

Louis Drapeau
director 

Albert J. Hillman
director

Sanford S. Wadler
Vice president,  
general counsel  
and Secretary

Ronald W. Hutton
treasurer

James R. Stark
corporate controller

Ruediger Naumann-Etienne
director

Alice N. Schwartz
director

Norman Schwartz
director

OTH ER ExECU TIV ES

Steve Binder
director,  
technology development, 
clinical diagnostics

Patrick Bugeon
group operations manager,  
france clinical diagnostics

OF FIC ERS

David Schwartz
chairman of the Board

Norman Schwartz
president and  
chief executive officer

Brad Crutchfield
Vice president and  
group manager,  
Life Science

John Goetz
Vice president and  
group manager,  
clinical diagnostics

Giovanni Magni
Vice president and  
international Sales manager

Christine A. Tsingos
Vice president and  
chief financial officer

John Bussell
manager,  
immunohematology

Francois Capit
Regional manager,  
Asia pacific

Patrick Carroll
manager,  
north America Sales,  
Life Science

Jean-Marc Chermette
manager, food Science

Colleen Corey
director, corporate  
human Resources

Michael Crowley
manager,  
north America Sales,  
clinical diagnostics

Diane Dahowski
u.S. group operations 
manager,  
clinical diagnostics

Patrice Deletoille
manager, Blood Virus

David Dutton
manager, clinical Systems

David Forrester
Regional manager, europe

Shannon Hall
manager,  
Laboratory Separations

John Hertia
group operations manager, 
Life Science

Michael Jackson
manager, Bioplex 2200

Scott Jenest
manager, manufacturing,  
Life Science

Leo Kaabi
manager, quality Systems

Bill Kuhlman
manager,  
process chromatography

Ann Madden
manager,  
clinical microbiology

Daniel Merle
manager,
Business development,
clinical diagnostics

Todd Morrill
manager,  
Business development,  
Life Science

John Senaldi
manager, protein function

Sanjiv Suri
Regional manager,  
emerging markets

Sadashi Suzuki
Regional manager, Japan

Annette Tumolo
manager, gene expression

ANNUAL MEETING

the Annual meeting of 
Stockholders will be held 
on tuesday, April 28, 2009 
at 4 pm, pacific time, at 
the corporate offices of 
the company in hercules, 
california.

Bio-Rad will provide without 
charge to each stockholder, 
upon written request to 
the Secretary, a copy of its 
2008 Annual Report filed 
with the Securities and 
exchange commission on 
form 10-k.

TRANSFER AGE NT

Computershare Investor 
Services LLC
250 Royall Street
canton, mA 02021

tel: 800-962-4284
fax: 312-601-2312
www.computershare.com

AUDITORS

Deloitte & Touche LLP
San francisco, california

COMMON STOCK

traded on the new york 
Stock exchange

class A common Stock
Symbol BIO

class B common Stock
Symbol BIOb

76  :  Bio-Rad Laboratories  |  Annual Report 2008

Bio-Rad Laboratories

1000 Alfred Nobel Drive
Hercules, CA 94547
510-724-7000
www.bio-rad.com