Quarterlytics / Industrials / Integrated Freight & Logistics / Cryoport, Inc.

Cryoport, Inc.

cyrx · NASDAQ Industrials
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Ticker cyrx
Exchange NASDAQ
Sector Industrials
Industry Integrated Freight & Logistics
Employees 1090
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FY2014 Annual Report · Cryoport, Inc.
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UNITED STATES  
SECURITIES AND EXCHANGE COMMISSION  
Washington, D.C. 20549  

Form 10-K  

  ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 

For the fiscal year ended March 31, 2014  

(cid:1)  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 

Commission File Number: 001-34632  

CRYOPORT, INC.  
(Exact Name of Registrant as Specified in its Charter)  

Nevada 
(State or other jurisdiction of  
incorporation or organization)  

88-0313393 
(I.R.S. Employer  
Identification No.)  

20382 Barents Sea Circle  
Lake Forest, CA 92630  
(Address of principal executive offices)  

(949) 470-2300  
(Registrant’s telephone number, including area code)  

Securities registered pursuant to Section 12(b) of the Act:  

Title of Each Class  
Common Stock, $0.001 par value  

Name of Each Exchange on Which Registered  
OTC Market 

Securities registered pursuant to Section 12(g) of the Act:  
Common Stock, $0.001  
Warrants to Purchase Common Stock  

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes (cid:1) No   

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes (cid:1) No   

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act 
of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject 
to such filing requirements for the past 90 days. Yes  No (cid:1)  

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data 
File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§ 229.405 of this chapter) during the preceding 12 months (or 
for such shorter period that the registrant was required to submit and post such files). Yes  No (cid:1)  

Indicate  by  check  mark  if  disclosure  of  delinquent  filers  pursuant  to  Item 405  of  Regulation S-K  is  not  contained  herein,  and  will  not  be 
contained,  to  the  best  of  registrant’s  knowledge,  in  definitive  proxy  or  information  statements  incorporated  by  reference  in  Part III  of  this 
Form 10-K or any amendment to this  
Form 10-K   

Indicate  by  check  mark  whether  the  registrant  is  a  large  accelerated  filer,  an  accelerated  filer,  a  non-accelerated  filer,  or  a  smaller  reporting 
company. See the definitions of “large  accelerated filer,” “accelerated filer” and “smaller reporting company” in  Rule 12b-2 of the Exchange 
Act. (Check one):  

Large accelerated filer (cid:1) 

Non-accelerated filer  (cid:1) (Do not check if a smaller reporting company) 

Accelerated filer 

Smaller reporting 
company 

(cid:1) 

 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
Indicate by check mark whether the Registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).    Yes   (cid:1)     No     

The aggregate market value of Common Stock held by non-affiliates of the registrant as of September 30, 2013 was $27,964,500(1) based on the 
closing sale price of such common equity on such date.  

As of June 13, 2014 there were 59,987,846 shares of the registrant’s common stock outstanding.  

(1)  Excludes 2,217,562  shares  of  common  stock held  by  directors and  officers,  and  any  stockholders whose  ownership  exceeds  five 

percent of the shares outstanding as of September 30, 2013.  

DOCUMENTS INCORPORATED BY REFERENCE  

   
   
   
   
   
   
  
  
Item 1.  Business 
Item 1A. Risk Factors 
Item 1B. Unresolved Staff Comments 
Item 2.  Properties 
Item 3.  Legal Proceedings 
Item 4.  Mine Safety Disclosures 

TABLE OF CONTENTS  

PART I 

 PART II  

Item 5.  Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities 
Item 6.  Selected Financial Data 
Item 7.  Management’s Discussion and Analysis of Financial Condition and Results of Operations 
Item 7A. Quantitative and Qualitative Disclosures About Market Risk 
Item 8.  Financial Statements and Supplementary Data 
Item 9.  Changes in and Disagreements with Accountants on Accounting and Financial Disclosure 
Item 9A. Controls and Procedures 
Item 9B. Other Information 

Item 10. Directors, Executive Officers and Corporate Governance 
Item 11. Executive Compensation 
Item 12. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters 
Item 13. Certain Relationships and Related Transactions, and Director Independence 
Item 14. Principal Accountant Fees and Services 

PART III 

Item 15. Exhibits and Financial Statement Schedules 
Signatures 

PART IV 

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FORWARD-LOOKING STATEMENTS  

Unless  the  context  otherwise  requires,  all  references  in  this  Annual  Report  on  Form 10-K  to  the  “Company”,  “we,”  “us,”  “our,”  or 
“Cryoport” refer to Cryoport, Inc. and our wholly owned subsidiary, Cryoport Systems, Inc. In addition, we own or have rights to the registered 
trademark Cryoport  ® (both alone and with a design  logo) and Cryoport Express  ® (both alone and with  a design logo). All other Company 
names,  registered  trademarks,  trademarks,  and  service  marks  included  in  this  Annual  Report  are  trademarks,  registered  trademarks,  service 
marks, or trade names of their respective owners.  

Cryoport, Inc.’s Annual Report on Form 10-K contains certain forward-looking statements. These forward-looking statements involve a 
number of risks and uncertainties. These forward-looking statements can generally be identified as such because the context of the statement will 
include  certain  words,  including  but  not  limited  to,  “believes,”  “may,”  “will,”  “expects,”  “intends,”  “estimates,”  “anticipates,”  “plans,”
“seeks,” “continues,” “predicts,” “potential,” “likely,” or “opportunity,” and also contains predictions, estimates and other forward-looking 
statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, 
as  amended,  and  in  reliance  upon  the  safe  harbor  provisions  of  the  Private  Securities  Litigation  Reform  Act  of  1995.  Such  forward-looking 
statements are based on the current beliefs of the Company’s management, as well as assumptions made by and information currently available 
to  the  Company’s  management.  Readers  of  this  Annual  Report  on  Form 10-K  should  not  put  undue  reliance  on  these  forward-looking 
statements,  which  speak  only  as  of  the  time  this  Annual  Report  on  Form 10-K  was  filed  with  the  Securities  and  Exchange  Commission  (the 
“SEC”). Reference is made in particular to forward-looking statements regarding the success of our products, product approvals, product sales, 
revenues,  development  timelines, product  acquisitions,  liquidity  and  capital  resources  and  trends.  Forward-looking  statements  are  inherently 
subject to risks and uncertainties, some of which cannot be predicted or quantified. Cryoport Inc.’s actual results may differ materially from the 
results projected in the forward-looking statements. Factors that might cause such a difference include, but are not limited to, those discussed in 
this Annual Report on Form 10-K, including the “Risk Factors” in “Item 1A — Risk Factors”, and in “Item 7 — Management’s Discussion and 
Analysis  of  Financial  Condition  and  Results  of  Operations”  included  in  Part II.  In  addition,  past  financial  or  operating  performance  is  not 
necessarily a reliable indicator of future performance, and you should not use our historical performance to anticipate results or future period 
trends. We can give no assurances that any of the events anticipated by the forward-looking statements will occur or, if any of them do, what 
impact they will have on our results of operations and financial condition. Except as required by law, we do not undertake to update any such 
forward-looking statements and expressly disclaim any duty to update the information contained in this Annual Report on Form 10-K.  

Item 1. Business  

Overview  

PART 1  

Through a combination of purpose-built proprietary packaging, information technology and specialized cold chain logistics knowhow, we 
provide frozen shipping logistics solutions to the life sciences industry. We view our solutions as disruptive to “older technologies” in that our 
solutions provide reliable, economic alternatives to existing solutions and services utilized for  frozen shipping in life  sciences including stem 
cells, cell lines, vaccines, diagnostic materials, semen, eggs, embryos, cord blood, bio-pharmaceuticals, infectious substances, and other items 
that require continuous exposure to frozen or cryogenic temperatures.  

Our Cryoport Express ® Solutions include sophisticated cloud-based logistics management software we have branded as the Cryoportal™, 
which supports the management of the entire shipment process through a single interface, including initial order input, document preparation, 
customs  clearance,  courier  management,  shipment  tracking,  issue  resolution,  and  delivery.  The  Cryoportal™  provides  unique  and  incisive 
information dashboards and validation documentation for every shipment. The Cryoportal™ records and retains a fully documented “chain-of-
custody” and, at the client’s option, “chain-of-condition” for every shipment, helping ensure that quality, safety, efficacy, and stability of shipped 
commodities are maintained throughout the process. This recorded and archived information allows our customers to meet exacting requirements 
necessary for scientific work and for regulatory purposes.  

Our  Cryoport  Express  ®  Solutions  also  include  our  liquid  nitrogen  dry  vapor  shippers  we  have  branded  as  our  Cryoport  Express  ® 
Shippers,  which  are  cost-effective  and  reusable  cryogenic  transport  containers  (patented  vacuum  flasks)  utilizing  innovative  liquid  nitrogen 
(“LN2”) “dry vapor” technology. Cryoport Express ® Shippers are International Air Transport Association (“IATA”) certified and validated to 
maintain  stable  temperatures  of  minus  150°  C  and  below  for  a  10-plus  day  dynamic  shipment  period.  The  Company  currently  features  two 
Cryoport Express ® Shipper models, the Standard Dry Shipper (holding up to 75-2.0 ml vials) and the High Volume Dry Shipper (holding up to 
500-2.0 ml vials).  

Amongst  our  solutions,  we  offer  a  “turnkey”  solution,  which  can  be  accessed  through  our  cloud-based  Cryoportal™  or  by  contacting 
Cryoport  Client  Care  for  order  entry.  Once  the  order  is  placed,  we  ship  a  fully  charged  Cryoport  Express®  Shipper  to  the  customer  who 
conveniently loads their frozen commodity into the inner chamber of the shipper.  The customer then closes the shipper and reseals the shipping 
box displaying the recipient’s address (“Flap A”) for pre-arranged carrier pick up.  Cryoport arranges for the pick-up of the parcel by a shipping 
service  provider  for  delivery  to  the  customer’s  intended  recipient.   The  recipient  simply  opens  the  box  and  shipper  and  removes  the  frozen 
commodity.  The recipient only needs to reseal the box, displaying the nearest Cryoport Operations Center address (“Flap B”) and set it out for 
pre-arranged carrier pick up. The Cryoport Express ® Shipper is returned to us for cleaning, quality assurance testing, recharging and reuse.  

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In late 2012, we shifted our focus from being a developer of cryogenic shippers and software to being a comprehensive frozen logistics 
solutions provider to the life sciences industry, which was accomplished by broadening our service offerings. Now, in addition to our “Turn-key 
Solution,” we also provide the following value-added solutions that were developed to address our various clients’ needs:  

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“  Customer  Staged  Solution  ,”  under  which  we  supply  an  inventory  of  our  Cryoport  Express®  Shippers  to  our  customer,  in  an 
uncharged state, enabling our customert (after training/certification) to charge them with liquid nitrogen and use our Cryoportal™ to 
enter orders with shipping and delivery service providers for the transportation of the package. Once the order is released, our customer 
services professionals monitor the shipment and the return of the shipper to us for cleaning, quality assurance testing and reuse. 

“  Customer  Managed  Solution  ,”  a  limited  customer  implemented  solution  whereby  we  supply  our  Cryoport  Express®  Shippers  to 
clients in a fully charged state, but leaving it to the client to manage the shipping, including the selection of the shipping and delivery 
service provider and the return of the shipper to us. Under this Solution, the customer accepts a significant level of risk for a successful 
shipment. 

“ Powered by Cryoport SM ,” is made available to providers of shipping and delivery services who seek to offer a “branded” cryogenic 
shipping solution as part of their service offerings. By negotiation, this solution can be private labeled as long as “ powered by Cryoport 
SM ” appears prominently  on the offering software interface  and prominently  on the packaging, which  is provided by the client after 
minimum volume requirements are met. 

“ Integrated Solution” is our most comprehensive and complex outsourcing solution. It usually involves our management of the entire 
cryogenic logistics process for our client, including the location of our employees at the client’s site to manage the client’s cryogenic 
logistics in total. 

“  Life  Science  Point-of-Care  Repository  Solution  ”  whereby  we  supply  our  Cryoport  Express  ®  Shippers  to  ship  and  store 
cryogenically preserved life science products for up to 6 days (or longer periods with substitute Shippers) at a point-of-care site, with 
the Cryoport Express  ® Shippers serving as a temporary freezer/repository enabling the efficient distribution of temperature sensitive 
allogeneic  cell-based  therapies  without  the  expense,  inconvenience,  and  potential  costly  failure  of  an  on-sight,  cryopreservation 
apparatus. Our customer services professionals monitor each shipment throughout the predetermined process including the shipment’s 
return  to  Cryoport  where  the  Cryoport  Express  ®  Shipper  is  cleaned,  tested  for  quality  assurance  and  then  returned  to  inventory  for 
reuse. 

“ Personalized Medicine and Cell-based Immunotherapy Solution ” whereby our Cryoport Express ® Solutions serves as an enabling 
technology  for  the  safe  manufacture  of  the  rapidly  expanding  autologous  cellular-based  immunotherapy  market  by  providing  a 
comprehensive logistics solution for the verified chain of custody and condition transport from, (a) the collection of the patient’s cells in 
a  hospital  setting,  to  (b)  a  central  processing  facility  where  they  are  manufactured  into  a  personalized  medicine,  to  (c)  the  safe, 
cryogenically preserved return of these irreplaceable cells to a point-of-care treatment facility.  The Cryoport Express ® Shippers can 
then serve as a temporary freezer/repository to allow the efficient distribution of this personalized medicine to patients when and where 
they  need  it  most  without  the  expense,  inconvenience,  and  potential  costly  failure  of  an  on-sight,  cryopreservation  apparatus.  Our 
customer  services  professionals  monitor  each  shipment  throughout  the  predetermined  process  including  the  shipment’s  return  to 
Cryoport where the Cryoport Express ® Shipper is cleaned, tested for quality assurance and then returned to inventory for reuse. 

One of our distribution partners is Federal Express Corporation (“FedEx”). We have an agreement with FedEx to provide frozen shipping 
logistics services through the combination of our purpose-built proprietary technologies and turnkey management processes. FedEx markets and 
sells Cryoport’s services for frozen temperature-controlled cold chain transportation as its FedEx ® Deep Frozen Shipping Solution on a non-
exclusive basis and at its sole expense. During fiscal year 2013, the Company worked closely with FedEx to further align its sales efforts and 
accelerate penetration within FedEx’s life sciences customer base through improved processes, sales incentives, joint customer calls and more 
frequent communication at the sales and executive level. In addition, FedEx has developed a FedEx branded version of the Cryoportal TM 
software platform, which is “ powered by Cryoport ” for use by FedEx and its customers giving them access to the full capabilities of our 
logistics management platform.  

In January 2013, we entered into a master agreement (“FedEx Agreement”) with FedEx renewing these services and providing FedEx with 
a non-exclusive license and right to use a customized version of our Cryoportal TM for the management of shipments made by FedEx customers. 
The FedEx Agreement became effective on January 1, 2013 and, unless sooner terminated as provided in the FedEx Agreement, expires on 
December 31, 2015.  

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Pursuant to an agreement with DHL Express (USA), Inc. (“DHL”), DHL biotechnology and life science customers have direct access to 
our cloud-based order entry and tracking portal to order Cryoport Express ® Shippers and receive preferred DHL shipping rates. The agreement 
covers DHL shipping discounts that may be used to support our customers using our Cryoport Express ® Solutions. In connection with the 
agreement, we have integrated our proprietary Cryoportal TM to DHL’s tracking and billing systems to provide DHL biotechnology and life 
science customers with a seamless way (“ powered by Cryoport ”) of shipping their critical biological material worldwide.  

In December 2012, we signed an agreement with Pfizer Inc. relating to Zoetis Inc. (formerly the animal health business unit of Pfizer Inc.) 

pursuant to which we were engaged to manage frozen shipments of a key poultry vaccine. Under this arrangement, the Company is providing 
on-site logistics personnel and its logistics management platform, the Cryoportal TM , to manage shipments from the Zoetis manufacturing site in 
the United States to domestic customers as well as various international distribution centers. As part of our logistics management services, 
Cryoport is constantly analyzing shipping data and processes to further streamline Zoetis’ logistics, ensuring products arrive at their destinations 
in specified conditions, on-time and with the optimum uses of resources. The Company manages Zoetis’ total fleet of dewar flask shippers used 
for this purpose, including liquid nitrogen shippers. In July 2013, the agreement was amended to expand Cryoport’s scope to manage all logistics 
of Zoetis’ key frozen poultry vaccine to all Zoetis’ international distribution centers as well as all domestic shipments of this vaccine. In October 
2013, the agreement was further amended to further expand Cryoport’s services to include the logistics management for a second poultry 
vaccine.  

In February 2014, we entered into a services agreement with Liventa Bioscience, Inc. (“Liventa”), a commercial stage biotechnology 
company focused on cell-based, advanced biologics in the orthopedic industry. Under this agreement, Liventa will be using Cryoport Express ® 
Solutions for the logistics of its cell-based therapies requiring cryogenic temperatures and also provide Cryoport Express ® Solutions to other 
biologics suppliers within the orthopedic arena. The agreement combines Cryoport’s proprietary, purpose-built cold chain logistics solutions for 
cell-based and advanced biologic tissue forms with Liventa’s distribution capability to orthopedic care providers. The implementation of 
Cryoport’s solution will eliminate dry ice shipping and related risks of degradation and also eliminate the need for expensive onsite cryogenic 
freezers for storage of cell-based orthopedic therapies. This will enable Liventa to better serve physicians at the point-of-care whether at 
hospitals, clinics, pharmacies, family practices, surgery centers or orthopedic offices.  

We offer our solutions to companies in the life sciences industry and specific verticals including manufacturers of stem cells and cell lines, 

diagnostic laboratories, bio-pharmaceuticals, contract research organizations, in-vitro fertilization, cord blood, vaccines, tissue, animal 
husbandry, and other producers of commodities requiring reliable frozen solutions for logistics. These companies operate within heavily 
regulated environments and as such, changing vendors and distribution practices typically require a number of steps; which may include the 
audit of our facilities, review of our procedures, qualifying us as a vendor, and performing test shipments. This process can take up to nine 
months or longer to complete prior to a potential customer adopting one or more of the Cryoport Express ® Solutions.  

Corporate History and Structure  

We are a Nevada corporation originally incorporated under the name G.T.5-Limited (“GT5”) on May 25, 1990. In connection with a Share 

Exchange Agreement, on March 15, 2005 we changed our name to Cryoport, Inc. and acquired all of the issued and outstanding shares of 
common stock of Cryoport Systems, Inc., a California corporation, in exchange for 2,410,811 shares of our common stock (which represented 
approximately 81% of the total issued and outstanding shares of common stock following the close of the transaction). Cryoport Systems, Inc., 
which was originally formed in 1999 as a California limited liability company, and subsequently reorganized into a California corporation on 
December 11, 2000, remains the operating company under Cryoport, Inc. Our principal executive offices are located at 20382 Barents Sea 
Circle, Lake Forest, CA 92630. The telephone number of our principal executive offices is (949) 470-2300, and our main corporate website is 
www.Cryoport.com. The information on, or that can be accessed through our website is not part of this Annual Report.  

The Company became public by a reverse merger with a shell company in May 2005. Over time the Company has transitioned from being 

a development company to a fully operational public company, providing cold chain logistics solutions to the biotechnology and life sciences 
industries globally.  

Since fiscal year 2011 the Company has taken significant steps towards commercialization of the Cryoport Express ® logistics solutions in 

validating, perfecting and expanding its features. The Company has now managed shipments of its Cryoport Express ® Shippers through its 
Cryoportal TM into and out of approximately 70 countries, handling a vast array of different biological products and specimens.  

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During fiscal year 2012, the Company completed the external validation of its Cryoport Express Standard Shipper to ISTA 7E standards 

and introduced the Cryoport Express ® High Volume Shipper in response to customer demand. The Company also set up its European 
distribution depot in Holland to better serve its customer base and support sales efforts in Europe.  

During fiscal year 2013, the Company elected Jerrell Shelton President and CEO, realigned its sales team and introduced a solutions sales 
and operating strategy. In addition, and as part of its global expansion plans, the Company set up its Asian distribution depot in Singapore. The 
Company also formed a Commercial Advisory Board (CAB) with Bill Taaffe, a founding member of ICON Clinical Research becoming its first 
member.  

Since the beginning of fiscal year 2014 the Company’s Board of Directors (“Board”) has added certain members to better align the 

experience and competencies of the directors with the Company’s strategic direction. In April 2013, Richard G. Rathmann, a fund manager, 
investor and advisor to life science companies over the past 20 years, was appointed to the Board.  In September 2013, Mr. Rathmann was 
elected Chairman of the Board. Also in September 2013, Mr. Edward Zecchini, an executive with over thirty years of experience in the 
healthcare and information technology industries was appointed to the Board. Most recently, in June 2014, the Board appointed Dr. Ramkumar 
Mandalam to the Board. Dr. Mandalam has over twenty years of experience in the development of biologics and is currently the President and 
Chief Executive Officer of Cellerant Therapeutics, Inc., a clinical-stage biotechnology company. The Company’s five person Board has four 
independent Board members.  

Cryoport Express ® Solutions  

Cryoport Express ® Solutions consist of the Cryoportal TM , a cloud-based logistics management software which programmatically assists 

in the management of all aspects of the logistics operations including the Cryoport Express ® Shippers and the Cryoport Express ® Smart Pak 
data logger. The Cryoportal TM is capable of producing Cryoport Express ® Analytics which reports shipment performance metrics and evaluates 
temperature-monitoring data collected by the data logger during shipment. Cryoport Express ® Solutions are focused on improving the reliability 
of frozen shipping while reducing our clients’ overall operating costs. This is accomplished by providing a complete end-to-end solution for the 
transport and monitoring of frozen or cryogenically preserved biological or pharmaceutical materials shipped primarily though integrators and 
specialty couriers. Certain of the intellectual property underlying our Cryoport Express ® Solutions (other than that related to the Cryoport 
Express ® Shippers) has been, and continues to be, developed under a contract with an outside software development company, with the 
underlying technology licensed to us for exclusive use in our field of use.  

Cryoportal TM  

The Cryoportal TM is used by Cryoport, our customers and our business partners to automate the entry of orders, prepare customs 
documentation and to facilitate status and location monitoring of shipped orders while in transit. It is used by Cryoport to assist in managing 
logistics operations and to reduce administrative costs typically provisioned through manual labor relating to order-entry, order processing, 
preparation of shipping documents and back-office accounting. It is also used to support the high level of customer service expected by the 
industry. Certain features of the Cryoportal TM reduce operating costs and facilitate the scaling of Cryoport’s business, but more importantly they 
offer significant value to the customer in terms of cost avoidance and risk mitigation. Examples of these features include automation of order 
entry, development of Key Performance Indicators (“KPI”) to support our efforts for continuous process improvements in our business, and 
programmatic exception monitoring to detect and sometimes anticipate delays in the shipping process, often before the customer or the shipping 
company becomes aware of them.  

The Cryoportal TM also serves as the communications center for the management, collection and analysis of Smart Pak data collected from 

Smart Pak data loggers in the field. Data is converted into pre-designed reports containing valuable and often actionable information that 
becomes the quality control standard or “pedigree” of the shipment. This information can be utilized by Cryoport to provide valuable feedback to 
our clients relating to their shipments.  

The Cryoportal™ software platform has been developed as a carrier-agnostic system, allowing the customer and the Cryoport Client Care 
team to work with multiple integrators, freight forwarders and/or couriers depending on the specific requirements and customer preferences. To 
increase operational efficiencies the Cryoportal™ has already been integrated with the tracking systems of FedEx, DHL and UPS and is planning 
to integrate with other key logistics providers.  

The Cryoportal TM was developed for time- and temperature-sensitive shipments that are required to maintain specific temperatures, such 
as ambient (between 20° and 25°C), chilled (between 2° and 8°C) or frozen (minus 10°C or less all the way down to cryogenic temperatures) to 
ensure that the shipped specimen is not subject to degradation or out of its designated “safe” range. While our current focus is on frozen 
shipments within the biotechnology and life sciences industries using the logistics solutions described herein, the use of the Cryoportal TM can 
and may be extended into other temperature ranges.  

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The Cryoport Express ® Shippers  

Our Cryoport Express ® Shippers are cryogenic dry vapor shippers capable of maintaining cryogenic temperatures of minus 150° Celsius 

or below for a dynamic shipping period of 10 or more days. A dry cryogenic shipper is a device that uses liquid nitrogen contained inside a 
vacuum insulated bottle which serves as a refrigerant to provide stable storage temperatures below minus 150° Celsius. Our Cryoport Express ® 
Shippers are designed to ensure that there is no pressure build up as the liquid nitrogen evaporates or spillage of liquid nitrogen. We have 
developed a proprietary retention system to ensure that liquid nitrogen stays inside the vacuum container, which allows the shipper to be 
designated as a dry shipper meeting IATA requirements. Biological or pharmaceutical specimens are stored in a specimen chamber, referred to 
as a “well” inside the container, refrigeration is provided by cold nitrogen gas evolving from the liquid nitrogen entrapped within the retention 
system. Specimens that may be transported using our cryogenic shipper include live cell scientific or pharmaceutical commodities such as cancer 
vaccines, diagnostic materials, semen, eggs and embryos, infectious substances and other items that require continuous exposure to frozen or 
cryogenic temperatures (e.g., temperatures below minus 150° Celsius).  

An important feature of our Cryoport Express ® Shippers is their compliance with the stringent packaging requirements of IATA Packing 
Instructions 602 and 650, respectively. These specifications include meeting internal pressure (hydraulic) and drop performance requirements. 
Under IATA guidelines, Cryoport Express ® Shippers are classified as “Non-hazardous” while dry ice and liquid nitrogen are classified as 
“Dangerous Goods.” Our shippers are also in compliance with ICAO regulations that prohibit egress of liquid nitrogen residue from the shipping 
packages. The International Civil Aviation Organization (“ICAO”) is a United Nations organization that develops regulations for the safe 
transport of dangerous goods by air.    

We currently offer two sizes of dry vapor shippers, the Cryoport Express ® Standard Shipper with a storage capacity of up to 75 0.2ml 

vials and the Cryoport Express ® High Volume Shipper that was introduced in January of 2012 with a capacity of up to 500 0.2ml vials.    

Cryoport Express ® Standard Shippers    

The Cryoport Express ® Standard Shippers are lightweight, low-cost, re-usable dry vapor liquid nitrogen storage containers that we believe 

combine the best features of packaging, cryogenics and high vacuum technology. A Cryoport Express ® Standard Shipper is composed of an 
aluminum metallic dewar flask, with a well for holding the biological material in the inner chamber. The dewar flask, or “thermos bottle,” is an 
example of a practical device in which the conduction, convection and radiation of heat are reduced as much as possible. The inner chamber of 
the shipper is surrounded by a high surface, low-density material which retains the liquid nitrogen in-situ by absorption, adsorption and surface 
tension. Absorption is defined as the taking up of matter in bulk by other matter, as in the dissolving of a gas by a liquid, whereas adsorption is 
the surface retention of solid, liquid or gas molecules, atoms or ions by a solid or liquid. This material absorbs liquid nitrogen several times 
faster than currently used materials, while providing the shipper with a hold time and capacity to transport biological materials safely and 
conveniently. The annular space between the inner and outer dewar chambers is evacuated to a very high vacuum (10-6 Torr). The specimen-
holding chamber has a primary cap to enclose the specimens, and a removable and replaceable secondary cap to further enclose the specimen-
holding container and to contain the liquid nitrogen. The entire dewar vessel is then wrapped in a plurality of insulating and cushioning materials 
and placed in a disposable outer packaging made of recyclable material. The Cryoport Express ® Standard Shipper has a storage capacity of up to 
75 0.2ml vials.    

The technology underlying the Cryoport Express ® Standard Shipper has been refined over the past five years. Our current shippers use 
aircraft grade aluminum and other lower weight materials, reducing freight cost which is based on dimensional weight. We maintain ongoing 
development efforts related to our shippers that are principally focused on material properties, particularly those properties related to our low 
temperature requirement, vacuum retention characteristics, such as the permeability of the materials, and lower weight materials in an effort to 
meet the life sciences market needs for achieving the lowest cost frozen and cryogenic shipping solution.    

Cryoport Express ® High Volume Shippers    

The Cryoport Express ® High Volume Shipper also uses a dry vapor liquid nitrogen (LN2) technology to maintain minus 150° C 
temperatures with a dynamic shipping endurance of 10 days. The Cryoport Express ® High Volume Shipper is based on the same dry vapor 
technology as Cryoport’s original standard dry shipper and utilizes an absorbent material to hold LN2, thus providing the extended endurance 
time and IATA validation as a non-hazardous shipping container. The high volume dry shipper is reusable and recyclable, making it a highly 
sustainable and cost effective method of transporting life science materials. The Cryoport Express ® High Volume Shipper has a storage capacity 
of up to 500 0.2ml vials.    

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We believe Cryoport Express ® Solutions are the best and most cost effective solution available in the biotechnology and life sciences 
markets and satisfy customer needs and scientific and regulatory requirements relating to the shipment of time- and temperature-critical, frozen 
and refrigerated transport of biological materials, such as stem cells, cell lines, pharmaceutical clinical trial samples, gene biotechnology, 
infectious materials handling, animal and human reproduction markets. Due to our proprietary technology and innovative design, our shippers 
are less prone to losing functional hold time when not kept in an upright position than the competing products because our proprietary dry vapor 
technology and innovative design prevent the spilling or leakage of the liquid nitrogen when the container is tipped or on its side which would 
otherwise adversely affect the functional hold time of the shipper.   An important feature of our Cryoport Express ® Shippers is their compliance 
with the stringent packaging requirements of IATA Packing Instructions 602 and 650, respectively. These specifications include meeting internal 
pressure (hydraulic) and drop performance requirements.    

The Cryoport Express ® Smart Pak  

Temperature monitoring is a high value feature from our customers’ perspective as it is an effective and reliable method to determine that 

the shipment materials were not damaged or did not experience degradation during shipment due to temperature fluctuations. Our Smart Pak 
System is a self-contained automated data logger capable of recording cryogenic temperatures of samples shipped in our Cryoport Express ® 
Shippers. The data-logging temperature probe is in the vapor plug of the shipper for the most accurate reading. The temperature mapping 
includes both the temperature inside the chamber (which is closest to the actual biomaterial) and the external temperature. This reading, 
combined with the mapping of every shipment check-in point, provides a holistic view of the complete shipping process. At the client’s election, 
shipments can have a full chain-of-custody and chain-of-condition with both data monitoring and analysis available.  

Chain-of-Condition  

Data monitoring starts with a custom-built data logger. The data logger can be set up to report during the shipment and/or after the 

shipment. For those shipments involving biologics or clinical trials or any other material that needs to be verified before receiving, the 
information recorded by the data logger can be downloaded to the data station onsite. Alternatively, Cryoport can upload the temperature data 
from the data logger for analysis to the Cryoportal TM upon return of the shipper. The Cryoportal TM also acts as the data repository for all 
shipment and temperature information, which the customer can access remotely through the internet. Chain of condition service is available at 
the client’s election.  

Chain-of-Custody  

When overlaid with the carrier check-ins, the data monitor and analysis also provides a chain of custody. The report from the data monitor 

serves as analysis for temperature monitoring of the entire shipment as well as a tampering warning. If the client has elected to have chain of 
condition monitoring, each time the container is opened there is a temperature record. The report identifies outlier temperature excursions such 
as opening the shipment in customs or tampering and thus will allow for more conclusive investigations to ensure that specimens were not 
adversely impacted during shipment.  

Cryoport Express ® Analytics  

The Cryoportal TM is an important information technology element of our business strategy and has been designed to support planned 

future features to allow for an expansion of our solutions offering. Analytics is a term used by IT professionals to refer to performance 
benchmarks or Key Performance Indicators (KPI’s) that management utilizes to measure performance against desired standards. Examples for 
analytics tracked through the Cryoportal TM include time-based metrics for order processing time and on-time deliveries by our shipping 
partners, as well as profiling shipping lanes to determine average transit times and predicting potential shipping exceptions based on historical 
metrics. The analytical results are being utilized by Cryoport to render consultative and proactive customer services.  

Biological Material Holders  

A patented containment bag is used in connection with the shipment of infectious or dangerous goods using the Cryoport Express® 
Shippers. Up to 75 cryovials (polypropylene vials with high-density polyethylene closures), set on aluminum canes are placed into an absorbent 
pouch, which is designed to contain the entire contents of all the vials in the event of leakage. This pouch is then placed in a watertight Tyvek 
bag (secondary packaging) capable of withstanding cryogenic temperatures, and then sealed. This bag is then placed into the well of the 
Cryoport Express ® Shipper.  

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Logistics Expertise and Support  

Cryoport’s client services professionals provide 24/7/365 live logistics and monitoring services with specialized knowledge in the domestic 
and global logistics of life sciences material requiring cryogenic temperatures. The Cryoport logistics professionals have validated shipping lanes 
in and out of more than 70 countries to date to ensure shipments maintain cryogenic temperatures and arrive securely and on time.  

Other Product Candidates and Development Activities  

We are continuing our research and development efforts to further refine our current technology as well as explore opportunities with 

partners to offer complementary packaging solutions for frozen temperature (minus 10° Celsius or less), chilled temperature (2° to 8° Celsius) 
and ambient temperature (between 20° and 25° Celsius) shipping markets.  

We also continue to further expand the functionality of our Cryoportal TM to ensure a high level of effectiveness and efficiency in the cold 

chain logistics process and to allow for intelligent and easy data monitoring and analysis.  

Government Regulation  

The shipping of diagnostic specimens, infectious substances and dangerous goods, whether via air or ground, falls under the jurisdiction of 

many state, federal and international agencies. The quality of the containers, packaging materials and insulation that protect a specimen 
determine whether or not it will arrive in a usable condition. Many of the regulations for transporting dangerous goods in the United States are 
determined by international rules formulated under the auspices of the United Nations.  

The ICAO is the United Nations organization that develops regulations (Technical Instructions) for the safe transport of dangerous goods 
by air. If shipment is by air, compliance with the rules established by IATA is required. IATA is a trade association made up of airlines and air 
cargo couriers that publishes annual editions of the IATA Dangerous Goods Regulations. These regulations interpret and add to the ICAO 
Technical Instructions to reflect industry practices. Additionally, the Centers for Disease Control (“CDC”) has regulations (published in the 
Code of Federal Regulations) for interstate shipping of specimens, and OSHA also addresses the safe handling of Class 6.2 Substances.  

Our Cryoport Express ® Shippers meet Packing Instructions 602 and 650 and are certified for the shipment of Class 6.2 Dangerous Goods 
per the requirements of the ICAO Technical Instructions for the Safe Transport of Dangerous Goods by Air and IATA. Our present and planned 
future versions of the Cryoport Smart Pak data logger will likely be subject to regulation by Federal Aviation Administration (“FAA”), Federal 
Communications Commission (“FCC”), Food and Drug Administration (“FDA”), IATA and possibly other agencies which may be difficult to 
determine on a global basis.  

We are also subject to numerous other federal, state and local laws relating to such matters as safe working conditions, manufacturing 
practices, environmental protection, fire hazard control, and disposal of hazardous or potentially hazardous substances. We may incur significant 
costs to comply with such laws and regulations now or in the future.  

Manufacturing and Raw Materials  

Manufacturing . Due to our currently adequate levels of dewar inventories, manufacturing is currently suspended. The component parts for 

our shippers are primarily manufactured at third party manufacturing facilities. We also have a warehouse at our facility in Lake Forest, 
California, where we are capable of manufacturing certain parts and to fully assemble our shippers. Most of the components that we use in the 
manufacture of our shippers are available from more than one qualified supplier. For some components, however, there are relatively few 
alternate sources of supply and the establishment of additional or replacement suppliers may not be accomplished immediately, however, we 
have identified alternate qualified suppliers. Should this occur, we believe that with our current level of shippers we have enough inventory to 
cover our forecasted demand.  

There are no specific agreements with any manufacturer nor are there any long term commitments to any manufacturer. We believe that 

most of the manufacturers currently used by us could be replaced within a short period of time as none have a proprietary component or a 
substantial capital investment specific to our shippers.  

Our production and manufacturing process incorporates innovative technologies developed for aerospace and other industries which are 

cost effective, easier to use and more functional than the traditional dry ice devices and other methods currently used for the shipment of 
temperature-sensitive materials. Our manufacturing process uses non-hazardous cleaning solutions, which are provided and disposed of by a 
supplier approved by the Environmental Protection Agency (the “EPA”). EPA compliance costs for us are therefore negligible.  

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Cryoport Express ® High Volume Shippers are purchased from a third party and modified to meet our specifications using our proprietary 

technology and know-how.  

Our data loggers have been acquired from a single source with the calibration done by an independent third party. We are currently 

considering adding alternate data loggers with greater range of functionality.  

Raw Materials . Various common raw materials are used in the manufacture of our shippers and in the development of our technologies. 

These raw materials are generally available from several alternate distributors and manufactures. We have not experienced any significant 
difficulty in obtaining these raw materials and we do not consider raw material availability to be a significant factor in our business.  

Patents and Proprietary Rights  

In order to remain competitive, we must develop and maintain protection on the proprietary aspects of our technologies. We rely on a 

combination of patents, copyrights, trademarks, trade secret laws and confidentiality agreements to protect our intellectual property rights. We 
currently own three registered United States trademarks and three issued United States patents primarily covering various aspects of our 
products.  

In addition, we have a pending patent application for various aspects of our shipper and web-portal, which includes, in part, various 
aspects of our business model referred to as the Cryoport Express® System. We have also filed a provisional patent application for a smart label 
which will communicate electronically with our data logger. We intend to file additional patent applications to strengthen our intellectual 
property rights.  

The technology covered by the above indicated issued patents relates to matters specific to the use of liquid nitrogen shippers in 

connection with the shipment of biological materials. The concepts include those of disposability, package configuration details, liquid nitrogen 
retention systems, systems related to thermal performance, systems related to packaging integrity, and matters generally relevant to the 
containment of liquid nitrogen. Similarly, the trademarks mentioned relate to the cryogenic temperature shipping activity. Issued patents and 
trademarks currently owned by us include:  

Type: 
Patent 
Patent 
Patent 

Trademark 
Trademark 

Issued 

No. 
6,467,642      Oct. 22, 2002    Oct. 21, 2022 
Sep. 19, 2000   
6,119,465     
Sep. 18, 2020 
Apr. 1, 2003    Mar 31, 2023 
6,539,726     

Expiration 

Feb. 2, 2019 
   7,748,667,3     
   7,737,454,1      Mar. 17, 2009    Mar. 16, 2019 

Feb. 3, 2009   

Our success depends in part upon our ability to develop proprietary products and technologies and to obtain patent coverage for these 

products and technologies. We intend to file trademark and patent applications covering any newly developed products, methods and 
technologies. However, there can be no guarantee that any of our pending or future filed applications will be issued as patents. There can be no 
guarantee that the U.S. Patent and Trademark Office or some third party will not initiate an interference proceeding involving any of our pending 
applications or issued patents. Finally, there can be no guarantee that our issued patents or future issued patents, if any, will provide adequate 
protection from competition.  

Patents provide some degree of protection for our proprietary technology. However, the pursuit and assertion of patent rights involve 
complex legal and factual determinations and, therefore, are characterized by significant uncertainty. In addition, the laws governing patent 
issuance and the scope of patent coverage continue to evolve. Moreover, the patent rights we possess or are pursuing generally cover our 
technologies to varying degrees. As a result, we cannot ensure that patents will issue from any of our patent applications, or that any of its issued 
patents will offer meaningful protection. In addition, our issued patents may be successfully challenged, invalidated, circumvented or rendered 
unenforceable so that our patent rights may not create an effective barrier to competition. Moreover, the laws of some foreign countries may not 
protect our proprietary rights to the same extent as the laws of the United States. There can be no assurance that any patents issued to us will 
provide a legal basis for establishing an exclusive market for our products or provide us with any competitive advantages, or that patents of 
others will not have an adverse effect on our ability to do business or to continue to use our technologies freely.  

We may be subject to third parties filing claims that our technologies or products infringe on their intellectual property. We cannot predict 

whether third parties will assert such claims against us or whether those claims will hurt our business. If we are forced to defend against such 
claims, regardless of their merit, we may face costly litigation and diversion of management’s attention and resources. As a result of any such 
disputes, we may have to develop, at a substantial cost, non-infringing technology or enter into licensing agreements. These agreements may be 
unavailable on terms acceptable to such third parties, or at all, which could seriously harm our business or financial condition.  

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We also rely on trade secret protection of our intellectual property. We attempt to protect trade secrets by entering into confidentiality 
agreements with third parties, employees and consultants, although, in the past, we have not always obtained such agreements. It is possible that 
these agreements may be breached, invalidated or rendered unenforceable, and if so, our trade secrets could be disclosed to our competitors. 
Despite the measures we have taken to protect our intellectual property, parties to such agreements may breach confidentiality provisions in our 
contracts or infringe or misappropriate our patents, copyrights, trademarks, trade secrets and other proprietary rights. In addition, third parties 
may independently discover or invent competitive technologies, or reverse engineer our trade secrets or other technology. Therefore, the 
measures we are taking to protect our proprietary technology may not be adequate.  

Customers and Distribution  

As a result of growing globalization, including such areas as biotechnology and life science, clinical trials, distribution of pharmaceutical 
products and reproductive medicine, the requirement for effective and reliable solutions for keeping clinical samples, pharmaceutical products 
and other specimen at frozen temperatures takes on added significance due to more complex shipping routes, extended shipping times, custom 
delays and logistics challenges. Today, such specimens are traditionally shipped in styrofoam cardboard insulated containers packed with dry 
ice, gel/freezer packs or a combination thereof. The current dry ice solutions have limitations that severely limit their effective use for both short 
and long-distances (e.g., international). Conventional dry ice shipments often require labor-intensive “re-icing” operations resulting in higher 
labor and shipping costs.  

We believe our patented Cryoport Express® Shippers, the Cryoportal™ and our logistics expertise make us well positioned to take 
advantage of the growing demand for effective and efficient international transport of temperature sensitive materials resulting from continued 
globalization. Of particular significance is the trend within the life sciences and biotechnology industries toward globalization.  

We provide domestic shipping solutions in situations where specimens must be kept at frozen temperatures and in regions where there is a 

high priority placed on maintaining the integrity of materials shipped at these temperatures.  

Pharmaceutical Clinical Trials . Every United States based pharmaceutical company developing a new drug must seek drug development 
protocol approval by the FDA. These clinical trials are to test the safety and efficacy of the potential new drug among other things. A significant 
amount of clinical trial activity is managed by a number of large Clinical Research Organizations (“CROs”).  

In connection with the clinical trials, due to globalization, companies can be enrolled from all over the world and may need to regularly 

submit a blood or other specimen at the local hospital, doctor’s office or laboratory. These samples are then sent to specified testing laboratories, 
which may be local or in another country. The testing laboratories will typically set the requirements for the storage and shipment of blood 
specimens. In addition, drugs used by the patients may require frozen shipping to the sites of the clinical trials. While both domestic and 
international shipping of these specimens is accomplished using dry ice today, international shipments especially present several problems, as 
dry ice, under the best of circumstances, can only provide freezing for one to two days in the absence of re-icing (which is quite costly). Because 
shipments of packages internationally can take longer than one to two days or be delayed due to flight cancellations, incorrect destinations, labor 
problems, ground logistics, customs delays and safety reasons, dry ice is not always a reliable and/or cost effective option. Clinical trial 
specimens are often irreplaceable because each one represents clinical data at a prescribed point in time, in a series of specimens on a given 
patient, who may be participating in a trial for years. Sample integrity during the shipping process is vital to retaining the maximum number of 
patients in each trial. Our shippers are ideally suited for this market, as our longer hold time ensures that specimens can be sent over long 
distances with minimal concern that they will arrive in a condition that will cause their exclusion from the trial. There are also many instances in 
domestic shipments where Cryoport Express ® Shippers will provide higher reliability and be cost effective.  

Furthermore, the IATA requires that all airborne shipments of laboratory specimens be transmitted in either IATA Instruction 650 or 602 

certified packaging. We have developed and obtained IATA certification of our Cryoport Express ® System, which is ideally suited for this 
market, in particular due to the elimination of the cost to return the reusable shipper.  

Biotechnology and Diagnostic Companies . The biotechnology market includes basic and applied research and development in diverse 
areas such as stem cells, cloning, gene therapy, DNA tumor vaccines, tissue engineering, genomics, and blood products. Companies participating 
in the foregoing fields rely on the frozen transport of specimens in connection with their research and development efforts, for which our 
Cryoport Express ® Shippers are ideally suited.  

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Cell Therapy Companies. Rapid advancements are underway in the research and development of cell based therapies, which involves 

cellular material being injected into a patient. In allogeniec cell therapy, the donor is a different person to the recipient of the cells. Autologous 
cell therapy is a therapeutic intervention that uses an individual’s cells, which are cultured and expanded outside the body, and reintroduced into 
the donor. Once cells are processed, in either case, they must be shipped cryogenically for which our Cryoport Express ® Shippers are ideally 
suited.  

Central Laboratories. With the increase and globalization of clinical studies and trials, logistics has become more complex and ensuring 
sample integrity has become more challenging. International courier costs are now consuming a significant portion of global protocol budgets. 
We believe laboratories performing the testing of samples collected during the conduct of these global multi-site studies are looking for reliable 
state-of-the-art logistics solutions.  

Pharmaceutical Distribution . The current focus for the Cryoport Express ® System also includes the area of pharmaceutical distribution. 

There are a significant number of therapeutic drugs and vaccines currently or anticipated soon to be undergoing clinical trials. After the FDA 
approves them for commercial marketing, it will be necessary for the manufacturers to have a reliable and economical method of distribution to 
the physician who will administer the product to the patient. It is likely that the most efficient and reliable method of distribution will be to ship a 
single dosage to the administering physician. These drugs are typically identified to individual patients and therefore will require a complete 
tracking history from the manufacturer to the patient. The most reliable method of doing this is to ship a unit dosage specifically for each patient. 
If such drugs require maintenance at frozen or cryogenic temperatures, each such shipment will require a frozen or cryogenic shipping package. 
Cryoport can provide the technology to meet this anticipated need.  

Distribution of Vaccines and Biologic Therapies. There are a variety of vaccines and other drugs or therapies that require distribution at 

frozen or cryogenic temperatures. We anticipate significant growth in this area, in particular therapies based upon stem cells. It is likely that the 
most efficient and reliable method of distribution will be to ship a single dosage or a limited supply to the physician for administration to a 
patient.  

In February 2013, we started providing comprehensive logistics management services for the lead poultry vaccine distribution of Zoetis, 

Inc. In October 2013, Zoetis engaged us to manage distribution of an additional vaccine.  

One of our strategic alliance partners, Liventa Bioscience, Inc., is, in part, basing its business strategy on using our Cryoport Express ® 

Shippers to deliver supplies of cell-based therapies to physicians, which will be able to keep the shippers at the physician’s facility for up to one 
week and thus avoid the need to invest in costly cryogenic refrigeration equipment for commodity storage. With the inclusion of our Cryoport 
Express ® Smart Pak data logger, Liventa and the physician will have assurance that cryogenic temperatures were maintained within the shipper.  

Fertility Clinics and In Vitro Fertilization (“IVF”) . Maintaining cryogenic temperatures during shipping and transfer of in vitro 
fertilization specimens like eggs, sperm, or embryos is critical for cell integrity in order to retain viability, stabilize the cells, and ensure 
reproducible results and successful IVF treatment. There are approximately 3,300 fertility clinics worldwide. Cryoport anticipates that this 
market will continue to grow; in the United States alone, the fertility market has grown to more than $4.0 billion with over 1.3 million women 
seeking treatment each year. In the worldwide market, it is reported that there are more than one billion IVF cycles per year and growing.  

Sales and Marketing  

We currently have two sales directors in the United States, one sales director in Europe, one inside sales representative focused on 

Reproductive Medicine/IVF and a part time senior director of marketing promoting the use of our Cryoport Express® Solutions on a direct basis, 
in addition to the distribution channels we are establishing. Given the global nature of our business, our sales and marketing initiatives should 
more thoroughly cover the Americas, Europe and Asia. For the fiscal year ended March 31, 2014, we had one customer that accounted for 30.8% 
of net revenues. No other single customer generated over 10% of our net revenues during 2014 and 2013.  

Our geographical revenues for the fiscal year ended March 31, 2014 were as follows:  

USA 
Europe 
Asia 
Rest of World 

11 

83.7 % 
6.7 % 
3.7 % 
5.9 % 

   
   
   
   
   
   
   
   
   
   
   
   
  
     
     
     
     
We renewed our agreement with FedEx and plan to further expand our revenues and marketing efforts through the establishment of 
additional strategic partnerships with global integrators and freight forwarders. Subject to available financial resources, we also plan to hiring 
additional sales and marketing personnel and implement marketing initiatives intended to increase awareness of the Cryoport Express ® 
Solutions.  

Cryoport Operations Centers  

In addition to the services provided through our facility in Lake Forest, California, we have contracted with third parties to run our 
European Operations Center (located in Leiden, Holland) and Asian Operations Center (located in Singapore). The operations centers provide 
warehousing, shipping, receiving, refurbishing and recycling services for our shipping containers. This approach is a cost-effective way to 
initiate operations outside of the US and allows us to scale up as our business grows globally. In March 2013, we shut down a small third-party 
operations center in New Delhi, India without impact on our business or customers.  

Industry and Competition  

Our products and services are sold into a rapidly growing segment of the logistics industry focused on the temperature sensitive packaging 

and shipping of biological materials. Expenditures for “value added” packaging for frozen transport have been increasing for the past several 
years and, due in part to continued globalization, are expected to continue to increase even more in the future as more domestic and international 
biotechnology firms introduce pharmaceutical products that require continuous refrigeration at cryogenic temperatures. We believe this will 
require a greater dependence on passively controlled temperature transport systems (i.e., systems having no external power source). In addition, 
we expect that industry standards and regulations will be introduced globally, requiring more comprehensive tracking and validation of shipping 
temperatures.  

We believe that growth in the following markets has resulted in the need for increased reliability, efficiencies and greater flexibility in the 

temperature sensitive segment of the logistics market:  

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

cell-based therapies 

gene and stem cell biotechnology 

cell lines 

vaccine production 

commercial drug product distribution 

clinical trials, including transport of tissue culture samples 

diagnostic specimens 

infectious sample materials 

inter/intra-laboratory diagnostic testing 

temperature-sensitive specimens 

biological samples, in general 

environmental sampling 

IVF 

animal husbandry 

Many of the biological products in these above markets require transport in a frozen state as well as the need for shipping containers which 
have the ability to maintain a frozen, cryogenic environment (e.g., minus 150° Celsius) for a period ranging from two to ten days (depending on 
the distance and mode of shipment). These products include stem cells, semen, embryo, tissue, tissue cultures, cultures of viruses and bacteria, 
enzymes, DNA materials, vaccines and certain pharmaceutical products.  

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One of the integral parts of our solutions are our Cryoport Express® Shippers that are based on a liquid nitrogen dry vapor technology. 

The following paragraphs compare our shippers with dry ice and liquid nitrogen shipping methods. Our solutions integrate the Cryoport 
Express® Shippers with our Cryoportal TM logistics software platform and our cold chain logistics know-how that are comprehensive and 
tailored to client requirements.  

Cryoport Express Shippers (Liquid Nitrogen Dry Vapor) compared to Dry Ice Shipments  

One problem faced by many companies operating in these specialized markets is the limited number of cryogenic shipping systems 
serving their needs. The currently adopted protocol and the most common method for packaging frozen transport in these industries is the use of 
solid-state carbon dioxide (dry ice). Dry ice is and has been used extensively in shipping to maintain a frozen state for a period of one to four 
days. Dry ice is used in the transport of many biological products, such as pharmaceuticals, laboratory specimens and certain infectious 
materials. The common approach to shipping these items via ground freight is to pack the product in a container, such as an expanded 
polystyrene (styrofoam) box or a molded polyurethane box, with a variable quantity of dry ice. The box is taped or strapped shut and shipped to 
its destination with freight charges based on its initial shipping weight. All dry ice shipping is considered dangerous goods shipping, requiring 
extra packaging steps and adding costs. It gives off carbon dioxide and sublimates unevenly and in short duration.  

With respect to shipments via specialized courier services, there is no standardized method or device currently in use for the purpose of 
transporting temperature-sensitive frozen biological specimens. One common method for courier transport of biological materials is to place 
frozen specimens, refrigerated specimens, and ambient specimens into a compartmentalized container, similar in size to a 55 quart Coleman or 
Igloo cooler. The freezer compartment in the container is loaded with a quantity of dry ice at minus 78° Celsius, while the refrigerated 
compartment at 8° Celsius utilizes ice substitutes.  

Two manufacturers of the polystyrene and polyurethane containers frequently used in the shipping and courier transport of dry ice frozen 

specimens are Insulated Shipping Containers, Inc. and Tegrant (formerly SCA Thermosafe). When these containers are used with dry ice, the 
average sublimation rate (e.g., the rate at which dry ice turns from a solid to a gaseous state) in a container with a 1 1 / 2 inch wall thickness is 
slightly less than three pounds per 24 hours. Other existing refrigerant systems employ the use of gel packs and ice substitutes for temperature 
maintenance. Gels and eutectic solutions (phase changing materials) with a wide range of phasing temperatures have been developed in recent 
years to meet the needs of products with varying specific temperature control requirements.  

The use of dry ice and ice substitutes, however, regardless of external packaging used, are frequently inadequate because they do not 
provide low enough storage temperatures and, in the case of dry ice, last for only a few days without re-icing. As a result, companies run the risk 
of increased costs due to lost specimens and additional shipping charges due to the need to re-ice.  

Some of the other disadvantages to using dry ice for shipping or transporting temperature sensitive products are as follows:  

• 

• 

• 

• 

• 

availability of a dry ice source; 

handling and storage of the dry ice; 

cost of the dry ice; 

compliance with local, state and federal regulations relating to the storage and use of dry ice; 

dangerous goods shipping regulations; 

•  weight of containers when packed with dry ice; 

• 

• 

securing a shipping container with a high enough R-value (which is a measure of thermal resistance) to hold the dry ice and 
product for the required time period; 

securing a shipping container that meets the requirements of IATA, the Department of Transportaion (‘DOT”), the CDC, and other 
regulatory agencies; and 

• 

emission of greenhouse gases (primarily carbon dioxide) into the environment. 

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Due to the limitations of dry ice, specimens that require frozen shipping are more securely shipped at true cryogenic temperatures using a 

service such as liquid nitrogen dry vapor shippers (Cryoport Express Shippers), or liquid nitrogen shippers where the specimen is kept over 
actual liquid nitrogen. However, liquid nitrogen is hazardous and has many pitfalls including safety and expense.  

Cryoport Express Shippers (Liquid Nitrogen Dry Vapor) compared to Liquid Nitrogen Dewars/Tanks  

There are distinct disadvantages when using liquid nitrogen compared to the dry vapor liquid nitrogen used in Cryoport Express ® 
Shippers. Liquid nitrogen dewars/tanks are classified as dangerous goods and cannot be shipped as parcel. In addition, the liquid nitrogen has to 
be disposed of prior to returning the dewar/tank to its origin. These issues add additional procedural steps and costs to the shipment. In addition, 
there is a risk of liquid nitrogen leakage if the dewar/tank tips to the side during transport, which can cause bodily injury and compromise the 
specimen being shipped. Due to the use of our proprietary technology, our Cryoport Express ® Shippers are not prone to leakage when on their 
side or inverted, thereby protecting the integrity of our shipper’s hold time and being safe for handling.  

While both liquid nitrogen dry vapor and liquid nitrogen shippers provide solutions to the issues encountered when shipping with dry ice, 
liquid nitrogen shippers have some draw backs. For example, the cost for a liquid nitrogen shipper typically can range from $650 to $4,000 per 
unit, which can substantially limit their use for the transport of many common biologics, particularly with respect to small quantities such as is 
the case with direct to the physician drug delivery. Because of the initial cost and limited production of these containers, they are designed to be 
reusable. However, the cost of returning these containers can be significant, particularly in international markets, because most applications 
require only one-way shipping. In addition, the logistics support of cryogenic shippers requires more sophisticated logistics management and 
discipline to ensure shippers are returned and recycled, especially for international shipments, which many companies do not have in place.  

Cryoport’s solutions are totally comprehensive and integrated for maximum reliability, economy and total effectiveness. Cryoport’s total 

logistics solution enables life sciences companies to utilize the superior liquid nitrogen dry vapor technology without having to make capital 
investments or developing in-house logistics expertise and systems by offering a complete solution which includes the cloud-based Cryoportal 
TM logistics management platform, the temperature monitoring system and the 24/7/365 logistics support. Cryoport allows the customer to 
outsource logistics and focus on its core competencies while maintaining visibility of all shipping related information.  

Within our intended biotechnology and life sciences markets for Cryoport Express ® Shippers, there is limited known direct competition. 

We compete with liquid nitrogen and dry ice solutions by reason of the improved and integrated hardware and software technology in our 
products including our comprehensive logistics management software and through the use of our service enabled business model. The Cryoport 
Express ® Solution provides a simple and cost effective solution for the frozen or cryogenic transport of biotech and life sciences materials. The 
Cryoportal TM assists with the management, scheduling and shipping of the Cryoport Express ® Shippers removing the burdens associated with 
other methods.  

Traditional dry ice shippers and liquid nitrogen tank suppliers, such as MVE/Chart Industries, Taylor Wharton and Air Liquide, offer 

various models of dry vapor liquid nitrogen shippers that are not as cost efficient for multi-use and multi-shipment purposes due to their 
significantly greater unit costs and unit weight (which may substantially increase the shipping cost). On the other hand, they are more established 
and have larger organizations and have greater financial, operational, sales and marketing resources, have a broader manufactured product 
offering of other liquid nitrogen products and more experience in research and development than we do.  

Factors that we believe give us a competitive advantage are attributable to our software and shipping container which allows our shipper to 

retain liquid nitrogen when placed in non-upright positions, the overall “leak- proofness” of our package which determines compliance with 
shipping regulations and the overall weight and volume of the package which determines shipping costs, and our business model represented by 
the merged integration of our shipper with Cryoportal TM and Smart Pak data logger into a seamless shipping, tracking and monitoring solution.  

Other companies that offer potentially competitive products include Industrial Insulation Systems, which offers cryogenic transport units 

and has partnered with Marathon Products Inc., a manufacturer and global supplier of wireless temperature data collecting devices used for 
documenting environmentally sensitive products through the cold chain and Kodiak Thermal Technologies, Inc. which offers, among other 
containers, a repeat use active-cool container that uses free piston stirling cycle technology. While not having their own shipping devices, 
BioStorage Technologies is potentially a competitive company through their management services offered for cold-chain logistics and long-term 
biomaterial storage. Cryogena offers a single use disposable LN2 shipper with better performance than dry ice, but it does not perform as well 
and is not as cost-effective as the Cryoport solution when all costs are considered. In addition, BioMatrica, Inc. is developing and offering 
technology that stabilizes biological samples and research materials at room temperature. They presently offer these technologies primarily to 
research and academic institutions; however, their technology may eventually enter the broader cold-chain market. Fisher BioServices, part of 
Thermo Fisher Scientific, provides cell therapy logistics services, maintaining cold chain from manufacturer to patient bedside.They provide 
customized solutions in biospecimen collection kits, biospecimen shipping, lab processing, biobanking and clinical trial support services.  

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Research and Development  

Our research and development efforts are focused on continually improving the features of our Cryoport Express ® Solutions including the 

cloud-based Cryoportal TM and the Cryoport Express ® Shippers. These efforts are expected to lead to the introduction of shippers of varying 
sizes based on market requirements, constructed of lower cost materials and utilizing high volume manufacturing methods that will make it 
practical to provide the cryogenic packages offered with the Cryoport Express ® Solutions. Alternative phase change materials in place of liquid 
nitrogen may be used to increase the potential markets these shippers can serve such as ambient and 2°-8°C markets. Our research and 
development expenditures for the fiscal years ended March 31, 2014 and 2013 were $409,111 and $425,446, respectively with the largest portion 
being spent on software maintenance and development.  

Employees  

The efforts of our employees are critical to our success. We believe that we have assembled a strong management team with the 
experience and expertise needed to execute our business strategy. We anticipate hiring additional personnel as needs dictate to implement our 
growth strategy. As of June 13, 2014, we had nineteen full-time employees, three consultants and one temporary employee.  

Insurance  

We currently maintain general liability insurance, with coverage in the amount of $1 million per occurrence, subject to a $2 million annual 

limitation. Claims may be made against us that exceed these limits. In fiscal year 2014, we did not experience any claims against our 
professional liability insurance. Our liability policy is an “occurrence” based policy. Thus, our policy is complete when we purchased it and 
following cancellation of the policy it continues to provide coverage for future claims based on conduct that took place during the policy term. 
However, our insurance may not protect us against all liability because our policies typically have various exceptions to the claims covered and 
also require us to assume some costs of the claim even though a portion of the claim may be covered. In addition, if we expand into new 
markets, we may not be aware of the need for, or be able to obtain insurance coverage for such activities or, if insurance is obtained, the dollar 
amount of any liabilities incurred could exceed our insurance coverage. A partially or completely uninsured claim, if successful and of 
significant magnitude, could have a material adverse effect on our business, financial condition and results of operations.  

We also maintain product liability insurance with coverage in the amount of $1,000,000 per year. In addition, we currently maintain cargo 

insurance for shipments for one customer, with coverage of up to $10,000 per shipment.  

ITEM1A.  RISK FACTORS 

This Annual Report on Form 10-K contains forward-looking information based on our current expectations. Because our actual results 
may differ materially from any forward-looking statements made by or on behalf of Cryoport, this section includes a discussion of important 
factors that could affect our actual future results, including, but not limited to, our potential product and service revenues, acceptance of our 
products and services, expenses, net income(loss) and earnings(loss) per common share.  

Risks Related to Our Financial Condition  

We have incurred significant losses to date and may continue to incur losses.  

We have incurred net losses in each fiscal year since we commenced operations. The following table represents net losses incurred for 

each of our last two fiscal years:  

Fiscal Year Ended March 31, 2014 
Fiscal Year Ended March 31, 2013 

   Net Loss    
   $ 19,565,400   
   $  6,382,400   

Our fiscal year ended March 31, 2014 loss of $19,565,400 included a one-time non-cash loss of $13,714,000 as a result of an induced debt 
conversion expense as described in ITEM 7.  Management's Discussion and Analysis of Financial Condition and Results of Operations under the 
“Results of Operations for Fiscal 2014 Compared to Fiscal 2013” section. As of March 31, 2014, we had an accumulated deficit of $85.9 
million. In order to achieve and sustain such revenue growth in the future, we must significantly expand our market presence and revenues from 
existing and new customers. We may continue to incur losses in the future and may never generate revenues sufficient to become profitable or to 
sustain profitability. Continuing losses may impair our ability to raise the additional capital required to continue and expand our operations.  

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Our auditors have expressed doubt about our ability to continue as a going concern.  

The Report of Independent Registered Public Accounting Firm to our March 31, 2014 consolidated financial statements includes an 
explanatory paragraph stating that the recurring losses and negative cash flows from operations since inception and our cash and cash equivalent 
balance at March 31, 2014 raise substantial doubt about our ability to continue as a going concern. The consolidated financial statements do not 
include any adjustments that might result from the outcome of this uncertainty.  

If we are unable to obtain additional funding, we may have to reduce or discontinue our business operations.  

As of June 13, 2014, we had cash and cash equivalents of $415,200. Therefore, our ability to continue and expand our operations is highly 

dependent on the amount of cash and cash equivalents on hand combined with our ability to raise additional capital to fund future operations.  

Recently, we funded our operations through a short-term bridge financing and a preferred stock offering. We plan to raise additional funds 

through an equity or debt offering to cover general working capital needs and sales and marketing initiatives to expand our customer base and 
increase revenues. If we are not able to raise sufficient funds and our projected revenues and cash-inflows are reduced or delayed, we may not 
have sufficient capital to operate through the second quarter of our fiscal year 2015 or beyond. We are currently exploring various arrangements 
with respect to securing additional funding. However, there can be no assurance that any additional financing on commercially reasonable terms, 
or at all, will be available when needed. The inability to obtain additional capital may reduce our ability to continue to conduct our business 
operations. Any additional equity financing will involve substantial dilution to our then existing stockholders. The uncertainties surrounding our 
future cash inflows have raised substantial doubt regarding our ability to continue as a going concern.  

Risks Related to Our Business  

Our agreements with global providers of shipping services may not result in a significant increase in our revenues or cash flow.  

We believe that establishing strategic alliances with global providers of shipping services, such as our agreements with FedEx, DHL and 
OCASA  can  drive  growth  in  our  revenues.  We  are  seeking  to  establish  similar  arrangements  with  other  providers  of  international  shipping 
services. Such alliances may enable us to provide a seamless, end-to-end shipping solution to customers of our alliance partners and allow us to 
leverage the established relationships with those customers.  

In January 2013, we entered into an agreement with FedEx, renewing FedEx’s right to, on a non-exclusive basis, promote, market and sell 
transportation of our shippers and our related value-added goods and services and providing FedEx with a non-exclusive license and right to use 
a customized version of our Cryoportal™ software platform for the management of shipments made by FedEx customers. In September 2013, 
we  entered  into  a  similar  agreement  with  OCASA,  Inc.  In  January  2014,  we  entered  into  a  letter  of  intent  with  DHL  confirming  our  mutual 
intentions  to  negotiate  an  additional  agreement  related  to  our  participation  in  DHL’s  efforts  to  expand  its  provision  of  cryogenic  shipping 
services to the life sciences industry.  

Because our agreements with FedEx, OCASA and DHL do not contain any requirement that they use a minimum level of our services (we 
do not anticipate the agreement under negotiation with DHL will include such volume commitments by DHL), there can be no assurance of any 
significant increase in our revenues or cash flows as a result of these strategic alliances.  

Our agreements with providers of vaccines and stem cell-based therapies may not result in a significant increase in our revenues or cash 
flow.  

We believe that establishing strategic relationships with manufacturers and distributors of treatments for animals and humans, such as our 
agreements with Zoetis, Inc. and Liventa Bioscience, Inc. can drive growth in our revenues. We are seeking to establish similar arrangements 
with other companies engaged in the life sciences industry, which require logistics solutions for the delivery of biologic material maintained at 
cryogenic temperatures.  

In December 2012, we entered an agreement with what became Zoetis, Inc. (in January 2013, Pfizer spun off its animal health business 
into  Zoetis,  Inc.,  a  public  company)  providing  for  us  to  manage  the  cryogenic  logistics  for  the  distribution  of  a  poultry  vaccine  from  its 
production  site  in  the  United  States.  Recently,  Zoetis  has  expanded  our  role  in  providing  them  assistance  in  managing  their  cryogenic 
distribution of their vaccines.  

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In February 2014, we entered an agreement with Liventa Bioscience, Inc. to act as its exclusive provider of cryogenic logistics of stem 
cell based therapies for orthopedic applications. Liventa intends to distribute its own line of therapies and to act as a distributor of other therapies 
to  orthopedic  health  care  providers  that  require  cryogenic  temperatures.  However,  we  do  not  expect  Liventa  to  begin  significant  use  of  our 
services prior to the second half of fiscal 2015.  

While we anticipate growth in shipments by Zoetis under our management and that Liventa will be successful in its efforts to distribute 
cell based biologic materials to the orthopedic market, there can be no assurance of any significant increase in our revenues or cash flows as a 
result of these strategic alliances.  

We  will  have  difficulty  increasing  our  revenues  if  we  experience  delays,  difficulties  or  unanticipated  costs  in  establishing  the  sales, 
distribution and marketing capabilities necessary to successfully commercialize our solutions.  

We plan to improve our sales, distribution, and marketing capabilities in the Americas, Europe, and Asia. It will be expensive and time-
consuming for us to develop our global marketing and sales network and thus we intend to rely on our strategic alliances with DHL, FedEx and 
OCASA. We further intend to seek to enter into additional strategic alliances with international providers of shipping services to incorporate use 
of  our  solutions  in  their  service  offerings.  We  may  not  be  able  to  provide  adequate  incentive  to  our  sales  force  or  to  establish  and  maintain 
favorable  distribution  and  marketing  collaborations  with  others  to  promote  our  solutions.  In  addition,  any  third  party  with  whom  we  have 
established a marketing and distribution relationship may not devote sufficient time to the marketing and sales of our solutions thereby exposing 
us  to  potential  expenses  in  exiting  such  distribution  agreements.  We,  and  any  of  our  alliance  partners,  must  also  market  our  services  in 
compliance with federal, state, local and international laws relating to the provision of incentives and inducements. Violation of these laws can 
result in substantial penalties. Therefore, if we are unable to successfully motivate and expand our marketing and sales force and further develop 
our sales and marketing capabilities, or if our alliance partners fail to promote our solutions, we will have difficulty increasing our revenues.  

Our  ability  to  grow  and  compete  in  our  industry  will  be  hampered  if  we  are  unable  to  retain  the  continued  service  of  our  key 
professionals or to identify, hire and retain additional qualified professionals.  

A critical factor to our business is our ability to attract and retain qualified professionals including key employees and consultants. We are 
continually  at  risk  of  losing  current  professionals  or  being  unable  to  hire  additional  professionals  as  needed.  If  we  are  unable  to  attract  new 
qualified  employees, our  ability to grow  will  be  adversely affected.  If  we are unable  to  retain  current employees  or  strategic consultants, our 
financial condition and ability to maintain operations may be adversely affected.  

We are dependent on new solutions and services.  

Our future revenue stream depends to a large degree on our ability to bring new solutions and services to market on a timely basis. We 
must continue to make significant investments in research and development in order to continue to develop new solutions and services, enhance 
existing  solutions  and  services,  and  achieve  market  acceptance  of  such  solutions  and  services.  We  may  incur  problems  in  introducing  new 
solutions and services.  

The adoption cycle of our target customers tends to be very lengthy, which continues to adversely affect our ability to increase revenues 
quickly.  

We  offer  our  solutions  primarily  to  companies  in  the  life  sciences  industry.  These  companies  operate  within  a  heavily  regulated 
environment and as such, changing vendors and distribution practices typically require a number of steps, which may include the audit of our 
facilities, review of our procedures, qualifying us as a vendor, and performing test shipments. This process can take several months or longer to 
complete, involving multiple levels of approval, prior to a company fully adopting our Cryoport Express ® Solutions. The logistics management 
of many companies is decentralized adding to the time need to effect adaptation of our solutions. In addition, any such adoption may be on a 
gradual basis such that the  customer progressively ramps up use  of our Cryoport Express  ® Solutions following adoption.  The slow adoption 
process continues to adversely affect our ability to increase revenues.  

We are dependent on an outside party for the continued development and maintenance of our Cryoportal™ software.  

Our proprietary Cryoportal™ is a logistics platform software used by our customers, business partners and client care team to automate the 
entry of orders, prepare customs documentation and facilitate status and location monitoring of shipped orders while in transit. The continued 
development of the Cryoportal™ platform is contracted with an outside software development company. If this developer becomes unable or 
unwilling to continue work on scheduled projects, and an alternative software development company cannot be secured, we may not be able to 
implement  needed  enhancements  to  the  system.  Furthermore,  if  we  terminate  our  agreement  with  our  current  software  developer  and  cannot 
reach  an agreement  or  fail to  fulfill  an agreement  for  the  termination, it is possible we  could lose our  license  to use  this  software.  Failure  to 
proceed  with  enhancements  or  the  loss  of  our  license  for  the  system  would  adversely  affect  our  ability  to  generate  new  business  and  serve 
existing customers, resulting in a reduction in revenue.  

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Our success depends, in part, on our ability to obtain patent protection for our solutions and business model, preserve our trade secrets, 
and operate without infringing the proprietary rights of others.  

Our policy is to seek to protect our proprietary position by, among other methods, filing United States patent applications related to our 
technology, inventions and improvements that are important to the development of our business. We have three issued U.S. patents; one pending 
patent,  and  one  recently  filed  provisional  patent  application,  all  relating  to  various  aspects  of  our  solutions  and  services.  Our  patents  or 
provisional patent application may be challenged, invalidated or circumvented in the future or the rights granted may not provide a competitive 
advantage. We intend to  vigorously  protect  and  defend our  intellectual  property. Costly  and time-consuming  litigation brought  by  us  may  be 
necessary  to enforce  our  patents  and  to protect  our  trade  secrets and  know-how,  or  to determine the  enforceability, scope  and  validity of  the 
proprietary rights of others.  

We also  rely  upon  trade  secrets,  technical know-how  and continuing technological  innovation to  develop  and  maintain our competitive 
position.  In  the  past  our  employees,  consultants,  advisors  and  suppliers  have  not  always  executed  confidentiality  agreements  and  invention 
assignment and work for hire agreements in connection with their employment, consulting, or advisory relationships. Consequently, we may not 
have adequate remedies available to us to protect our intellectual property should one of these parties attempt to use our trade secrets or refuse to 
assign any rights he or she may have in any intellectual property he or she developed for us. Additionally, our competitors may independently 
develop substantially equivalent proprietary information and techniques or otherwise gain access to our proprietary technology, or we may not 
be able to meaningfully protect our rights in unpatented proprietary technology.  

While we are not aware of any third party that is infringing any of our patents or trademarks nor do we believe that we are infringing on 
the patents or trademarks of any other person or organization, we cannot assure you that our current and potential competitors and other third 
parties have not filed (or in the future will not file) patent applications for (or have not received or in the future will not receive) patents or obtain 
additional proprietary rights that will prevent, limit or interfere with our ability to make, use or sell our solutions either in the United States or 
internationally.  Additionally,  we  may  face  assertions  of  claims  by  holders  of  patents  alleging  that  we  are  infringing  upon  their  patent  rights 
which claims are without merit, but may result in our incurring substantial costs of defense.  

Our  solutions  and  services  may  contain  errors  or  defects,  which  could  result  in  damage  to  our  reputation,  lost  revenues,  diverted 
development resources and increased service costs and litigation.  

Our solutions and services must meet stringent requirements and we must develop our services and solutions quickly to keep pace with the 
rapidly changing market. Solutions as sophisticated as ours could contain undetected errors or defects, especially when first introduced or when 
new  equipment  or  versions  of  our  software  are  released.  If  our  solutions  are  not  free  from  errors  or  defects,  we  may  incur  an  injury  to  our 
reputation,  lost  revenues,  diverted  development  resources,  increased  customer  service  and  support  costs,  and  litigation.  The  costs  incurred  in 
correcting any product errors or defects may be substantial and could adversely affect our business, results of operations and financial condition.  

If we experience manufacturing delays, interruptions in production, or delays in procurement of shippers manufactured by third parties, 
then we may experience customer dissatisfaction and our reputation could suffer.  

If we fail to produce enough shippers at our own manufacturing facility or at a third party manufacturing facility, or if we fail to complete 
our  shipper  recycling  processes  as  planned,  we  may  be  unable  to  deliver  shippers  to  our  customers  on  a  timely  basis,  which  could  lead  to 
customer dissatisfaction and could harm our reputation and ability to compete. We currently acquire various component parts for our shippers 
from  various  independent  manufacturers  in  the  United  States.  We  would  likely  experience  significant  delays  or  cessation  in  producing  our 
shippers if a labor strike, natural disaster or other supply disruption were to occur at any of our main suppliers. If we are unable to procure a 
component  from  one  of  our  manufacturers,  we  may  be  required  to  enter  into  arrangements  with  one  or  more  alternative  manufacturing 
companies, which may cause delays in producing our shippers. In addition, because we depend (in part) on third party manufacturers, our profit 
margins may be lower, which will make it more difficult for us to achieve profitability. To date, we have not experienced any material delay that 
has adversely impacted our operations. As our business develops it becomes more likely that such problems could arise.  

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If  we  experience  delays  or  interruption  in  shipping  due  to  factors  outside  of  our  control,  such  disruption  could  lead  to  customer 
dissatisfaction and harm our reputation.  

We rely on third party shipment and carrier services to transport our shippers containing biological material. These third party operations 
could be subject to natural disasters, adverse weather conditions, other business disruptions, and carrier error, which could cause delays in the 
delivery of our shippers, which in turn could cause serious harm to the biological material being shipped. As a result, any prolonged delay in 
shipment,  whether  due  to  technical  difficulties,  power  failures,  break-ins,  destruction  or  damage  to  carrier  facilities  as  a  result  of  a  natural 
disaster, fire, or any other reason, could result in damage to the contents of the shipper. If we are unable to cause the delivery of our shippers in a 
timely matter and without damage, this could also harm our operating results and our reputation, even if we are not at fault.  

Our  Cryoportal™  software  platform  may  be  subject  to  intentional  disruption  that  could  adversely  impact  our  reputation  and  future 
revenues.  

We have implemented our Cryoportal™ software platform which is used by our customers and business partners to automate the entry of 
orders, prepare customs documentation and facilitate status and location monitoring of shipped orders while in transit. Although we believe we 
have  sufficient  controls  in  place  to  prevent  intentional  disruptions,  we  could  be  a  target  of  cyber  attacks  specifically  designed  to  impede  the 
performance of the Cryoportal™ software platform. Similarly, experienced computer programmers may attempt to penetrate our Cryoportal™ 
software  platform  in  an  effort  to  search  for  and  misappropriate  proprietary  or  confidential  information  or  cause  interruptions  of  our  services. 
Because the techniques used by such computer programmers to access or sabotage networks change frequently and may not be recognized until 
launched against a target, we may be unable to anticipate these techniques. Our activities could be adversely affected and our reputation, brand 
and future sales could be harmed if such intentionally disruptive efforts were successful.  

Our solutions and services may expose us to liability in excess of our current insurance coverage.  

Our solutions and services involve significant risks of liability, which may substantially exceed the revenues we derive from them. We 
cannot predict the magnitude of these potential liabilities. We currently maintain general liability insurance, with coverage in the amount of $1 
million per occurrence, subject to a $2 million annual limitation, and product liability insurance with a $1 million annual coverage limitation. 
Claims may be made against us that exceed these limits.  

Our liability policy is an “occurrence” based policy. Thus, our policy is complete when we purchased it and following cancellation of the 
policy  it  continues  to  provide  coverage  for  future  claims  based  on  conduct  that  took  place  during  the  policy  term.  Our  insurance  coverage, 
however, may not protect us against all liability because our policies typically have various exceptions to the claims covered and also require us 
to assume some costs of the claim even though a portion of the claim may be covered. In addition, if we expand into new markets, we may not 
be  aware  of  the  need  for,  or  be  able  to  obtain  insurance  coverage  for  such  activities  or,  if  insurance  is  obtained,  the  dollar  amount  of  any 
liabilities incurred could exceed our insurance coverage. A partially or completely uninsured claim, if successful and of significant magnitude, 
could have a material adverse effect on our business, financial condition and results of operations.  

Complying  with  certain  regulations  that  apply  to  shipments  using  our  solutions  can  limit  our  activities  and  increase  our  cost  of 
operations.  

Shipments using our solutions and services are subject to various regulations in the various countries in which we operate. For example, 
shipments using our solutions may be required to comply with the shipping requirements promulgated by the CDC, the Occupational Safety and 
Health Organization (“OSHA”), the DOT as well as rules established by the IATA and the ICAO. Additionally, our data logger may be subject 
to regulation and certification by the FDA, FCC, and FAA. We will need to ensure that our solutions and services comply with relevant rules and 
regulations to make our solutions and services marketable, and in some cases compliance is difficult to determine. Significant changes in such 
regulations could require costly changes to our solutions and services or prevent use of our shippers for an extended period of time while we 
seek  to  comply  with  changed  regulations.  If  we  are  unable  to  comply  with  any  of  these  rules  or  regulations  or  fail  to  obtain  any  required 
approvals, our ability to market our solutions and services may be adversely affected. In addition, even if we are able to comply with these rules 
and  regulations,  compliance  can  result  in  increased  costs.  In  either  event,  our  financial  results  and  condition  may  be  adversely  affected.  We 
depend on our business partners and unrelated and frequently unknown third party agents in foreign countries to act on our behalf to complete 
the importation process and to make delivery of our shippers to the final user. The failure of these third parties to perform their duties could 
result in damage to the contents of the shipper resulting in customer dissatisfaction or liability to us, even if we are not at fault.  

If we cannot compete effectively, we will lose business.  

Our services and solutions are positioned to be competitive in the life sciences cold-chain logistics market. While there are technological 
and marketing barriers to entry, we cannot guarantee that the barriers we are capable of producing will be sufficient to defend the market share 
we wish to gain against current and future competitors. Our principal competitive considerations in our market include:  

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• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

financial resources to allocate to proper marketing and an appropriate sales effort 

acceptance of our solutions model 

acceptance of our solutions including per use fee structures and other charges for services 

keeping up technologically with ongoing development of enhanced features and benefits 

reductions in the delivery costs of competitors’ solutions 

the ability to develop and maintain and expand strategic alliances 

establishing our brand name 

our ability to deliver our solutions to our customers when requested 

our timing of introductions of new solutions, and services 

financial resources to support working capital needs and required capital investments in infrastructure 

Current and prospective competitors have substantially greater resources, more customers, longer operating histories, greater name recognition 
and more established relationships in the industry. As a result, these competitors may be able to develop and expand their networks and product 
offerings more quickly, devote greater resources to the marketing and sale of their solutions and adopt more aggressive pricing policies. In 
addition, these competitors have entered and will likely continue to enter into business relationships to provide additional solutions competitive 
to those we provide or plan to provide .  

If we successfully develop products and/or services, but those products and/or services do not achieve and maintain market acceptance, 
our business will not be profitable.  

The degree of acceptance of our Cryoport Express ® Solutions or any future products or services by our current target markets, and any 

other markets to which we attempt to sell our products and services, and our profitability and growth will depend on a number of factors 
including, among others:  

• 

• 

• 

• 

• 

• 

our shippers’ ability to perform and preserve the integrity of the materials shipped 

relative convenience and ease of use of our shipper and/or Cryoportal TM 

availability of alternative products 

pricing and cost effectiveness 

effectiveness of our or our collaborators’ sales and marketing strategy 

the adoption cycles of our targeted customers 

If any products or services we may develop do not achieve market acceptance, then we may not generate sufficient revenue to achieve or 

maintain profitability.  

In addition, even if our products and services achieve market acceptance, we may not be able to maintain that market acceptance over time 
if new products or services are introduced that are more favorably received than our products and services, are more cost effective, or render our 
products obsolete.  

We may not be able to compete with our competitors in the industry because many of them have greater resources than we do.  

We expect to continue to experience significant and increasing levels of competition in the future. In addition, there may be other 
companies which are currently developing competitive products and services or which may in the future develop technologies and products that 
are comparable, superior or less costly than our own. For example, some cryogenic equipment manufacturers with greater resources currently 
have solutions for storing and transporting cryogenic liquid and gasses and may develop storage solutions that compete with our products. 
Additionally, some specialty couriers with greater resources currently provide dry ice transportation and may develop other products in the 
future, both of which compete with our products. A competitor that has greater resources than us may be able to bring its product to market faster 
than we can and offer its product at a lower price than us to establish market share. We may not be able to successfully compete with a 
competitor that has greater resources and such competition may adversely affect our business.  

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
20 

Risks Relating to Our Current Financing Arrangements  

Certain of our existing stockholders own and have the right to acquire a substantial number of shares of common stock.  

As of June 13, 2014, our directors, executive officers and beneficial owners of 5% or more of our outstanding common stock beneficially 

owned 12,779,856 shares of common stock (without regard to beneficial ownership limitations contained in certain warrants) assuming their 
exercise of all outstanding warrants and options that are exercisable within 60 days of June 13, 2014 or approximately 18.2% of our outstanding 
common stock. Of these shares of common stock, 3,449,625 shares, or approximately 5.4% of our common stock, will be beneficially owned by 
Cranshire Capital Master Fund. As such, the concentration of beneficial ownership of our common stock may have the effect of delaying or 
preventing a change in control of Cryoport and may adversely affect the voting or other rights of other holders of our common stock.  

The sale of substantial shares of our common stock may depress our stock price.  

As of June 13, 2014, there were 59,987,846 shares of our common stock outstanding. Substantially all of these shares of common stock are 

eligible for trading in the public market. The market price of our common stock may decline if our stockholders sell a large number of shares of 
our common stock in the public market, or the market perceives that such sales may occur.  

We could also issue up to 82,641,062 shares of our common stock including shares to be issued upon the exercise of outstanding warrants 

and options or reserved for future issuance under our stock incentive plans, as further described in the following table:  

Common stock issuable upon exercise of outstanding warrants 
Common stock issuable upon exercise of outstanding options or reserved for future incentive awards under our 

stock incentive plans 

Total 

Number of  
Shares of  
Common Stock 

Issuable or  
Reserved for  
Issuance 

63,045,977   

19,595,085   

82,641,062   

Of the total options and warrants outstanding as of March 31, 2014, options and warrants exercisable for an aggregate of 68,170,852 
shares of common stock would be considered dilutive to the value of our stockholders’ interest in Cryoport because we would receive upon 
exercise of such options and warrants an amount per share that is less than the market price of our common stock on March 31, 2014.  

Our stock price has been and will likely continue to be volatile.  

The market price of our common stock has been highly volatile and could fluctuate widely in price in response to various factors, many of 

which are beyond our control, including, but not limited to:  

• 

• 

• 

• 

• 

• 

• 

• 

• 

technological innovations or new solutions and services by us or our competitors 

additions or departures of key personnel 

sales of our common stock 

our ability to execute our business plan 

our operating results being below expectations 

loss of any strategic relationship 

industry developments 

economic and other external factors 

period-to-period fluctuations in our financial results 

21 

   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
 
  
  
  
  
  
     
     
  
     
    
     
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
In addition, the securities markets have from time to time experienced significant price and volume fluctuations that are unrelated to the 
operating  performance  of  particular  companies.  These  market  fluctuations  may  also  materially  and  adversely  affect  the  market  price  of  our 
common stock and warrants.  

If equity research analysts do not publish research or reports about our business or if they issue unfavorable commentary or downgrade 
our common stock and warrants, the price of our common stock and warrants could decline.  

The trading market for our common stock and warrants relies in part on the research and reports that equity research analysts publish about 

us and our business. We do not control these analysts. The price of our common stock and warrants could decline if one or more equity analyst 
downgrades our stock or if analysts downgrade our stock or issue other unfavorable commentary or cease publishing reports about us or our 
business.  

We have not paid dividends on our common stock in the past and do not expect to pay dividends in the foreseeable future. Any return on 
investment may be limited to the value of our common stock.  

We have never paid cash dividends on our common stock and do not anticipate paying cash dividends in the foreseeable future. The 
payment of dividends on our common stock will depend on our earnings, financial condition and other business and economic factors affecting 
us at such time as the Board of Directors may consider the payment of any such dividends. If we do not pay dividends, our common stock may 
be less valuable because a return on your investment will only occur if the price of our common stock appreciates.  

We  need  additional  capital,  and  the  sale  of  additional  shares  of  common  stock  or  other  equity  securities  could  result  in  additional 
dilution to our stockholders.  

Our current cash and cash equivalents and anticipated cash flow from operations are insufficient to meet our cash needs. We require 
additional cash resources to fund our operations and may require additional funds in the future due to changed business conditions or other future 
developments, including any investments or acquisitions we may decide to pursue. The sale of additional equity securities, or debt securities 
convertible into equity securities, could result in additional dilution to our stockholders. The incurrence of indebtedness would result in increased 
debt service obligations and could result in operating and financing covenants that would restrict our operations.  

Our Articles of Incorporation allows our Board of Directors to issue up to 2,500,000 shares of “blank check” preferred stock.  

Our  Articles  of  Incorporation  allows  our  Board  of  Directors  to  issue  up  to  2,500,000  shares  of  “blank  check”  preferred  stock,  without 
action  by  our  stockholders.  Currently,  800,000  shares  of  the  authorized  preferred  stock  have  been  designated  as  Class  A  Preferred  Stock 
(“Preferred Stock”). We contemplate the Preferred Stock offered will utilize up to 800,000 of such authorized shares resulting in the potential for 
1,700,000 shares that could be issued on terms determined by our Board of Directors, and may have rights, privileges and preferences superior to 
those of our the Preferred Stock previously offered hereby or the common stock into which it may be converted. Without limiting the foregoing, 
(i) such shares of preferred stock could have liquidation rights that are senior to the liquidation preference applicable to our common stock and 
Preferred Stock, (ii) such shares of preferred stock could have voting or conversion rights, which could adversely affect the voting power of the 
holders of our common stock and Preferred Stock and (iii) the ownership interest of holders of our common stock will be diluted following the 
issuance of any such shares of preferred stock. In addition the issuance of such shares of blank check preferred stock could have the effect of 
discouraging, delaying or preventing a change of control of our Company.  

22 

   
   
   
   
   
   
   
   
   
   
  
Provisions in our bylaws and Nevada law might discourage, delay or prevent a change of control of our Company or changes in our 
management and, as a result, may depress the trading price of our common stock.  

Provisions of our bylaws and Nevada law may discourage, delay or prevent a merger, acquisition or other change in control that 
stockholders may consider favorable, including transactions in which you might otherwise receive a premium for your shares of our common 
stock. The relevant bylaw provisions may also prevent or frustrate attempts by our stockholders to replace or remove our management. These 
provisions include advance notice requirements for stockholder proposals and nominations, and the ability of our Board of Directors to make, 
alter or repeal our bylaws.  

Absent approval of our Board of Directors, our bylaws may only be amended or repealed by the affirmative vote of the holders of at least a 

majority of our outstanding shares of capital stock entitled to vote.  

In addition, Section 78.438 of the Nevada Revised Statutes prohibits a publicly-held Nevada corporation from engaging in a business 

combination with an interested stockholder (generally defined as a person which together with its affiliates owns, or within the last three years 
has owned, 10% of our voting stock, for a period of three years after the date of the transaction in which the person became an interested 
stockholder) unless the business combination is approved in a prescribed manner.  

The existence of the foregoing provisions and other potential anti-takeover measures could limit the price that investors might be willing to 
pay in the future for shares of our common stock. They could also deter potential acquirers of our Company, thereby reducing the likelihood that 
you could receive a premium for your common stock in an acquisition.  

Even  though  we  are  not  incorporated  in  California,  we  may  become  subject  to  a  number  of  provisions  of  the  California  General 
Corporation Law.  

Section 2115(b) of the California Corporations Code imposes certain requirements of California corporate law on corporations organized 
outside California that, in general, are doing more than 50% of their business in California and have more than 50% of their outstanding voting 
securities held of record by persons residing in California. While we are not currently subject to Section 2115(b), we may become subject to it in 
the future.  

The following summarizes some of the principal differences which would apply if we become subject to Section 2115(b).  

Under both Nevada and California law, cumulative voting for the election of directors is permitted. However, under Nevada law 

cumulative voting must be expressly authorized in the Articles of Incorporation and our Amended and Restated Articles of Incorporation do not 
authorize cumulative voting. If we become subject to Section 2115(b), we may be required to permit cumulative voting if any stockholder 
properly requests to cumulate his or her votes.  

Under Nevada law, directors may be removed by the stockholders only by the vote of two-thirds of the voting power of the issued and 
outstanding stock entitled to vote. However, California law permits the removal of directors by the vote of only a majority of the outstanding 
shares entitled to vote. If we become subject to Section 2115(b), the removal of a director may be accomplished by a majority vote, rather than a 
vote of two-thirds, of the stockholders entitled to vote.  

Under California law, the corporation must take certain steps to be allowed to provide for greater indemnification of its officers and 
directors than is provided in the California Corporation Code. If we become subject to Section 2115(b), our ability to indemnify our officers and 
directors, to the extent permitted in our Articles of Incorporation, Bylaws and under Nevada law, may be limited by California law.  

Nevada law permits distributions to stockholders as long as, after the distribution, (i) the corporation would be able to pay its debts as they 
become due and (ii) the corporation’s total assets are at least equal to its liabilities and preferential dissolution obligations. Under California law, 
distributions may be made to stockholders as long as the corporation would be able to pay its debts as they mature and either (i) the corporation’s 
retained earnings equal or exceed the amount of the proposed distributions, or (ii) after the distributions, the corporation’s tangible assets are at 
least 125% of its liabilities and the corporation’s current assets are at least equal to its current liabilities (or, 125% of its current liabilities if the 
corporation’s average operating income for the two most recently completed fiscal years was less than the average of the interest expense of the 
corporation for those fiscal years). If we become subject to Section 2115(b), we will have to satisfy more stringent financial requirements to be 
able to pay dividends to our stockholders. Additionally, stockholders may be liable to the corporation if we pay dividends in violation of 
California law.  

California law permits a corporation to provide “supermajority vote” provisions in its Articles of Incorporation, which would require 
specific actions to obtain greater than a majority of the votes, but not more than 66 2 / 3 percent. Nevada law does not permit supermajority vote 
provisions. If we become subject to Section 2115(b), it is possible that our stockholders would vote to amend our Articles of Incorporation and 
require a supermajority vote for us to take specific actions.  

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Under California law, in a disposition of substantially of all the corporation’s assets, if the acquiring party is in control of or under 
common control with the disposing corporation, the principal terms of the sale must be approved by 90 percent of the stockholders. Although 
Nevada law does contain certain rules governing interested stockholder business combinations, it does not require similar stockholder approval. 
If we become subject to Section 2115(b), we may have to obtain the vote of a greater percentage of the stockholders to approve a sale of our 
assets to a party that is in control of, or under common control with, us.  

California law places certain additional approval rights in connection with a merger if all of the shares of each class or series of a 

corporation are not treated equally or if the surviving or parent party to a merger represents more than 50 percent of the voting power of the other 
corporation prior to the merger. Nevada law does not require such approval. If we become subject to Section 2115(b), we may have to obtain the 
vote of a greater percentage of the stockholders to approve a merger that treats shares of a class or series differently or where a surviving or 
parent party to the merger represents more than 50% of the voting power of the other corporation prior to the merger.  

California law requires the vote of each class to approve a reorganization or a conversion of a corporation into another entity. Nevada law 
does not require a separate vote for each class. If we become subject to Section 2115(b), we may have to obtain the approval of each class if we 
desire to reorganize or convert into another type of entity.  

California law provides greater dissenters’ rights to stockholders than Nevada law. If we become subject to Section 2115(b), more 

stockholders may be entitled to dissenters’ rights, which may limit our ability to merge with another entity or reorganize.  

Our stock is deemed to be penny stock.  

Our stock is currently traded on the OTCQB, operated by the OTC Markets Group, Inc., and is subject to the “penny stock rules” adopted 
pursuant to Section 15(g) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). The penny stock rules apply to companies 
not  listed  on  a  national  exchange  whose  common  stock  trades  at  less  than  $5.00  per  share  or  which  have  tangible  net  worth  of  less  than 
$5,000,000 ($2,000,000 if the company has been operating for three or more years). Such rules require, among other things, that brokers who 
trade “penny stock” to persons other than “established customers” complete certain documentation, make suitability inquiries of investors and 
provide investors with certain information concerning trading in the security, including a risk disclosure document and quote information under 
certain circumstances. Penny stocks sold in violation of the applicable rules may entitle the buyer of the stock to rescind the sale and receive a 
full refund from the broker.  

Many brokers have decided not to trade “penny stock” because of the requirements of the penny stock rules and, as a result, the number of 
broker-dealers willing to act as market makers in such securities is limited. In the event that we remain subject to the “penny stock rules” for any 
significant period, there may develop an adverse impact on the market, if any, for our securities. Because our securities are subject to the “penny 
stock  rules,”  investors  will  find  it  more  difficult  to  dispose  of  our  securities.  Further,  for  companies  whose  securities  are  traded  in  the  OTC 
Bulletin  Board,  it  is  more  difficult:  (i)  to  obtain  accurate  quotations,  (ii)  to  obtain  coverage  for  significant  news  events  because  major  wire 
services, such as the Dow Jones News Service, generally do not publish press releases about such companies, and (iii) to obtain needed capital.  

If  we  fail  to  maintain  an  effective  system  of  internal  control  over  financial  reporting,  we  may  not  be  able  to  accurately  report  our 
financial results, and current and potential stockholders may lose confidence in our financial reporting.  

We are required by the SEC to establish and maintain adequate internal control over financial reporting that provides reasonable assurance 
regarding the reliability of our financial reporting and the preparation of financial statements in accordance with generally accepted accounting 
principles. We are likewise required, on a quarterly basis, to evaluate the effectiveness of our internal controls and to disclose any changes and 
material weaknesses in those internal controls.  

As described in Item 9A of this Annual Report on Form 10-K for the year ended March 31, 2014, no material weaknesses were identified 

and we determined that our internal control over financial reporting was effective as of March 31, 2014.  

Any failure to maintain such internal controls in the future could adversely impact our ability to report our financial results on a timely and 
accurate basis. If our financial statements are not accurate, investors may not have a complete understanding of our operations. Likewise, if our 
financial statements are not filed on a timely basis as required by the SEC and the OTC Bulletin Board, we could face severe consequences from 
those authorities. In either case, there could result a material adverse effect on our business. Inferior internal controls could also cause investors 
to lose confidence in our reported financial information, which could have a negative effect on the trading price of our stock.  

24 

   
   
   
   
   
   
   
   
   
   
   
   
  
Our publicly-filed SEC reports are reviewed by the SEC from time to time and any significant changes required as a result of any such 
review may result in material liability to us and have a material adverse impact on the trading price of our common stock.  

The reports of publicly-traded companies are subject to review by the SEC from time to time for the purpose of assisting companies in 
complying with applicable disclosure requirements and to enhance the overall effectiveness of companies’ public filings, and reviews of such 
reports are now required at least every three years under the Sarbanes-Oxley Act of 2002. SEC reviews may be initiated at any time, and we 
could  be  required  to  modify  or  reformulate  information  contained  in  prior  filings  as  a  result  of  an  SEC  review.  Any  modification  or 
reformulation of information contained in such reports could be significant and could result in material liability to us and have a material adverse 
impact on the trading price of our common stock.  

ITEM 1B.  Unresolved Staff Comments 

Not applicable.  

ITEM 2. 

Properties 

We do not own real property. We currently lease two facilities, with approximately 12,000 square feet of corporate, research and 

development, and warehouse facilities, located in Lake Forest, California (“Lake Forest Facility”) and approximately 4,100 square feet of 
corporate offices located in San Diego, California (“San Diego Facility”). In June 2010, the Company entered into a third amendment to the 
Lake Forest Facility lease and extended the lease for sixty months commencing July 1, 2010 with a right to cancel the lease with a minimum of 
120 day written notice at any time after December 31, 2012. On November 28, 2011, the Company entered into a lease agreement for the 
corporate offices in San Diego for a thirty six month period ending December 31, 2014.  

The Company currently makes base lease payments of approximately $17,000 per month, due at the beginning of each month. We believe 
that these facilities are adequate, suitable and of sufficient capacity to support our immediate needs. Additional space may be required, however, 
as we expand our research and development, manufacturing and selling and marketing activities.  

ITEM 3. 

Legal Proceedings 

In the ordinary course of business, we are at times subject to various legal proceedings and disputes, including product liability claims. We 

currently are not aware of any such legal proceedings or claim that we believe will have, individually or in the aggregate, a material adverse 
effect on our business, operating results or cash flows. It is our practice to accrue for open claims based on our historical experience and 
available insurance coverage.  

ITEM 4.  Mine Safety Disclosures 

Not applicable  

PART II  

ITEM 5.  Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities 

Common Stock  

As of June 13, 2014 there were 59,987,846 shares of common stock outstanding and 232 stockholders of record. On June 13, 2014, the 

closing sale price of our common stock was $0.48 per share.  

Market Information  

Our common stock is traded on the OTCQB, operated by the OTC Markets Group, Inc. under the symbol “CYRX”. The high and low 

closing sale prices of our common stock reported by OTCQB during each quarter ended March 31, 2014 and 2013 were as follows:  

Year 2014: 

Fourth Quaxrter Ended March 31, 2014 
Third Quarter Ended December 31, 2013 
Second Quarter Ended September 30, 2013 
First Quarter Ended June 30, 2013 

Year 2013 

Fourth Quarter Ended March 31, 2013 
Third Quarter Ended December 31, 2012 
Second Quarter Ended September 30, 2012 
First Quarter Ended June 30, 2012 

High  

Low  

   $ 
   $ 
   $ 
   $ 

   $ 
   $ 
   $ 
   $ 

0.57      $ 
0.55      $ 
0.52      $ 
0.56      $ 

0.61      $ 
0.39      $ 
0.51      $ 
0.70      $ 

0.34   
0.30   
0.23   
0.16   

0.33   
0.11   
0.19   
0.37   

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
    
  
  
  
    
  
  
  
  
  
      
  
    
  
  
      
  
    
25 

Unregistered Equity Issuances  

We did not issue any unregistered securities during the year ended March 31, 2014 that were not otherwise disclosed in a previously filed 

Quarterly Report on Form 10-Q or Current Report on Form 8-K.  

Dividends  

No dividends on common stock have been declared or paid by the Company. The Company intends to employ all available funds for the 

development of its business and, accordingly, does not intend to pay any cash dividends in the foreseeable future.  

Securities Authorized for Issuance Under Equity Compensation  

The information included under Item 12 of Part III of this Annual Report is hereby incorporated by reference into this Item 5 of Part II of 

this Annual Report.  

Recent Sale of Unregistered Securities  

The following is a summary of transactions by the Company during period covered by this report involving the issuance and sale of the 
Company’s securities that were not registered under the Securities Act of 1933, as amended (the “Securities Act”) and that have not previously 
been included in a Quarterly Report on Form 10-Q. All securities sold by the Company were sold to individuals, trusts or others who were 
accredited investors as defined under Regulation D under the Securities Act.  

 In the fourth quarter of 2014, the Company issued to certain accredited investors 5% Bridge Notes in the original principal amount of 

$1,352,000, including a note in the amount of $50,000 issued to Jerrell Shelton, the Company’s Chief Executive Officer as well as a note in the 
amount of $100,000 issued to GBR Investments, LLC, of which Richard Rathmann, a Director of the Company, is the manager. All principal 
and interest under the 5% Bridge Notes will be due on June 30, 2014. In connection therewith, the Company also granted such accredited 
investors warrants to purchase 676,000 shares of common stock at an exercise price of $0.49 per share. The warrants are exercisable on May 31, 
2014 and expire on December 31, 2018.  

Emergent Financial Group, Inc. served as the Company’s placement agent in connection with the placement of the 5% Bridge Notes and 

earned a commission of 9% of the original principal balance of such notes, excluding the note issued to Jerrell Shelton and GBR Investments, or 
$108,180 at the time of the original issuance of such notes.  

The issuance of the securities of the Company in the above transaction were deemed to be exempt from registration under the Securities 

Act by virtue of Section 4(2) thereof or Regulation D promulgated there under, as a transaction by an issuer not involving a public offering. With 
respect to the transaction listed above, no general solicitation was made by either the Company or any person acting on the Company’s behalf; 
the securities sold are subject to transfer restrictions; and the certificates for the shares contain an appropriate legend stating that such securities 
have not been registered under the Securities Act and may not be offered or sold absent registration or pursuant to an exemption therefrom.  

ITEM 6. 

Selected Financial Data 

The following selected financial data has been derived from audited consolidated financial statements of the Company for each of the five 

years in the period ended March 31, 2014. You should read the following financial information together with the information under 
“Management’s Discussion and Analysis of Financial Condition and Results of Operations” and our consolidated financial statements and 
related notes included elsewhere in this annual report. The information set forth below is not necessarily indicative of our future financial 
condition or results of operations.  

26 

   
   
   
   
   
   
   
   
   
   
       
   
   
   
  
Statement of Operations Data:  

2014  

Revenues 
Cost of revenues 
Gross margin (loss) 

   $ 

Selling, general and administrative 
Research and development 

Loss from operations 
Debt conversion expense 
Interest income 
Interest expense 
Loss on sale of fixed assets 
Change in fair value of derivative liabilities   
Other expense, net 

Net loss before provision for income 
taxes 
Provision for income taxes 

Net loss 
Net loss per share — basic and diluted 

   $ 
   $ 

2,660      $ 
2,223     
437     
5,106     
409     
(5,078 )   
(13,714 )   
—    
(784 )   
—    
21     
(8 )   

(19,563 )   
2     

(19,565 )    $ 
(0.40 )    $ 

2013  

Years ended March 31,  
2012  
(In thousands, except per share data) 

2011  

1,101      $ 
1,588     
(487 )   
5,412     
425     
(6,324 )   
—    
—    
(72 )   
—    
16     
—    

(6,380 )   
2     
(6,382 )    $ 
(0.17 )    $ 

556      $ 

476      $ 

1,392     
(836 )   
6,106     
492     
(7,434 )   
—    
12     
(528 )   
—    
119     
—    

1,303     
(827 )   
4,321     
449     
(5,597 )   
—    
16     
(619 )   
—    
50     
—    

(7,831 )   
2     
(7,833 )    $ 
(0.27 )    $ 

(6,150 )   
2     
(6,152 )    $ 
(0.46 )    $ 

2010  

118   
718   
(600 ) 
3,313   
284   
(4,197 ) 
—  
8   
(7,029 ) 
(9 ) 
5,577   
—  

(5,650 ) 
2   
(5,652 ) 
(1.13 ) 

Balance Sheet Data:  

2014  

2013  

As of March 31,  
2012  
(In thousands) 

2011  

2010  

Cash, cash equivalents 
Working capital (deficit) 
Total assets 
Convertible notes and accrued interest, net    
Long term obligations, less current portion   
Total stockholders’ equity (deficit) 

   $ 

370      $ 

563      $ 

(2,903 )   
1,710     
1,622     
—    
(2,304 )   

(1,539 )   
1,756     
1,304     
1,322     
(2,063 )   

4,618      $ 
4,024     
6,214     
338     
1,375     
3,730     

9,278      $ 
6,760     
11,031     
2,401     
1,423     
5,948     

3,630   
1,995   
4,777   
2,502   
1,478   
(915 ) 

ITEM 7.  Management's Discussion and Analysis of Financial Condition and Results of Operations 

This Annual Report on Form 10-K contains forward-looking statements within the meaning of the federal securities laws. These statements 
are subject  to risks  and uncertainties  that  could cause actual results and  events to differ materially from  those expressed or implied  by  such 
forward-looking statements. For a detailed discussion of these risks and uncertainties, see the “Risk Factors” section in Item 1A of Part I of this 
Form 10-K. We caution the reader not to place undue reliance on these forward-looking statements, which reflect management’s analysis only 
as of the date of this Form 10-K. We undertake no obligation to update forward-looking statements to reflect events or circumstances occurring 
after the date of this Form 10-K.  

The following discussion and analysis should be read in conjunction with our consolidated financial statements and the related notes to 

those statements contained elsewhere in this Annual Report on Form 10-K.  

Overview  

We provide leading edge frozen logistics solutions to the life sciences industry. Since 2011, through the completion of the combination 

of our purpose-built and patented packaging, purpose-built cold chain logistics software platform information technologies and developed 
logistics knowhow known as “total turnkey management” we have provided logistics solutions for frozen shipping to the life sciences industry. 
Our solutions are disruptive to “older technologies” as they are more comprehensive and provide reliable, economic alternatives to existing 
products and services utilized for frozen shipping in the life sciences industry including stem cells, cell lines, vaccines, diagnostic materials, 
semen and embryos for in-vitro fertilization, cord blood, bio-pharmaceuticals, infectious substances and other items that require continuous 
exposure to frozen or cryogenic temperatures. In addition, our solutions can contribute significantly to the effectiveness, reliability and efficiency 
of clinical trials.  

Cryoport Express ® Solutions include a cloud-based logistics management software platform branded as the Cryoportal TM . The 
Cryoportal TM  software platform supports the management of the entire logistics process through a single interface which includes initial order 
input, document preparation, customs clearance, courier management, shipment tracking, issue resolution, and delivery. Cryoport’s total turnkey 
logistics solutions offer convenience, reliability and cost effectiveness, while the use of recyclable and reusable components provides “green,” 
environmentally friendly solutions. The Cryoportal TM provides an array of unique information dashboards and validation documentation for 
every shipment.  

27 

   
   
   
   
   
   
   
   
   
  
  
  
  
  
    
    
    
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
    
    
    
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
Integral to our logistics solutions are our Cryoport Liquid Nitrogen Dry Vapor Shippers (Cryoport Express ® Shippers), which provide 

packaging that is cost-effective and reusable cryogenic transport containers (patented vacuum flasks) utilizing innovative liquid nitrogen (LN2) 
“dry vapor” technology. Cryoport Express ® Shippers are non-hazardous, IATA (International Air Transport Association) certified, and validated 
to maintain stable temperatures of minus 150° Celsius for a 10-plus day dynamic shipment period. The Company currently features two 
Cryoport Express ® Shipper models, the Standard Dry Shipper (holding up to approximately 75-2.0 ml vials) and the High Volume Dry Shipper 
(holding up to approximately 500-2.0 ml vials).  

The Cryoport Express ® Solutions includes document preparation, intervention capability, and recording and retaining a fully documented 
“chain-of-custody” and, at the client’s option, “chain-of-condition” for every shipment, helping ensure that quality, safety, efficacy, and stability 
of shipped commodities shipped. This recorded and archived information allows our customers to meet the exacting requirements necessary for 
scientific work and for regulatory purposes. When a customized solution is not required, Cryoport Express ® Solutions can be used by customers 
as a “turnkey” solution through direct access to the cloud-based Cryoportal TM or by contacting Cryoport Client Care for order entry tasks. 
Cryoport provides 24/7/365 logistics services through its Client Care team and also provides complete training and process management services 
to support each client’s specific requirements.  

Amongst  our  solutions,  we  offer  a  “turnkey”  solution,  which  can  be  accessed  through  our  cloud-based  Cryoportal™  or  by  contacting 
Cryoport  Client  Care  for  order  entry.  Once  the  order  is  placed,  we  ship  a  fully  charged  Cryoport  Express®  Shipper  to  the  customer  who 
conveniently loads their frozen commodity into inner chamber of the shipper.  The customer then closes the shipper and reseals the shipping box 
displaying  the  recipient’s  address  (“Flap  A”)  for  pre-arranged  carrier  pick  up.   Cryoport  arranges  for  the  pick-up  of  the  parcel  by  a  shipping 
service  provider  for  delivery  to  the  customer’s  intended  recipient.   The  recipient  simply  opens  the  box  and  shipper  and  removes  the  frozen 
commodity.  The recipient only needs to reseal the box, displaying the nearest Cryoport Operations Center address (“Flap B”) and set out for 
pre-arranged carrier pick up. The Cryoport Express ® Shipper is returned to us for cleaning, quality assurance testing, recharging and reuse of the 
Cryoport Express® Shipper.  

In late 2012, we shifted our focus from being a developer of cryogenic shippers and software to being a comprehensive frozen logistics 
solutions provider to the life sciences industry, which was accomplished by broadening our service offerings. Now, in addition to our “Turn-key 
Solution,” we also provide the following value-added solutions that were developed to address our various clients’ needs:  

• 

• 

• 

• 

• 

• 

“  Customer  Staged  Solution  ,”  under  which  we  supply  an  inventory  of  our  Cryoport  Express®  Shippers  to  our  customer,  in  an 
uncharged  state,  enabling  our  customer (after  training/certification)  to  charge  them  with  liquid nitrogen  and  use  our  Cryoportal™  to 
enter orders with shipping and delivery service providers for the transportation of the package. Once the order is released, our customer 
services professionals monitor the shipment and the return of the shipper to us for cleaning, quality assurance testing, and reuse. 

“ Customer Managed Solution ,” a limited customer implemented solution, whereby we supply our Cryoport Express® Shippers to 
clients in a fully charged state, but leaving it to the client to manage the shipping, including the selection of the shipping and delivery 
service provider and the return of the shipper to us. Under this Solution, the customer accepts a significant level of the risk for a 
successful shipment. 

“ Powered by Cryoport SM ” is made available to providers of shipping and delivery services who seek to offer a “branded” cryogenic 
shipping solution as part of their service offerings. By negotiation, this solution can be private labeled as long as “ powered by Cryoport 
SM ” appears prominently  on the offering software interface  and prominently  on the packaging, which  is provided by the client after 
minimum volume requirements are met. 

“ Integrated Solution ” is our most comprehensive and complex outsourcing solution. It usually involves our management of the entire 
cryogenic logistics process for our client, including the location of our employees at the client’s site to manage the client’s cryogenic 
logistics, in total. 

“  Life  Science  Point-of-Care  Repository  Solution  ”  whereby  we  supply  our  Cryoport  Express  ®  Shippers  to  ship  and  store 
cryogenically preserved life science products for up to 6 days (or longer periods with substitute Shippers) at a point-of-care site, with 
the Cryoport Express  ® Shippers serving as a temporary freezer/repository enabling the efficient distribution of temperature sensitive 
allogeneic  cell-based  therapies  without  the  expense,  inconvenience,  and  potential  costly  failure  of  an  on-sight,  cryopreservation 
apparatus. Our customer services professionals monitor each shipment throughout the predetermined process including the shipment’s 
return  to  Cryoport  where  the  Cryoport  Express  ®  Shipper  is  cleaned,  tested  for  quality  assurance  and  then  returned  to  inventory  for 
reuse. 

“ Personalized Medicine and Cell-based Immunotherapy Solution ” whereby our Cryoport Express ® Solutions serves as an enabling 
technology  for  the  safe  manufacture  of  the  rapidly  expanding  autologous  cellular-based  immunotherapy  market  by  providing  a 
comprehensive logistics solution for the verified chain of custody and condition transport from, (a) the collection of the patient’s cells in 
a  hospital  setting,  to  (b)  a  central  processing  facility  where  they  are  manufactured  into  a  personalized  medicine,  to  (c)  the  safe, 
cryogenically preserved return of these irreplaceable cells to a point-of-care treatment facility.  The Cryoport Express ® Shippers can 
then serve as a temporary freezer/repository to allow the efficient distribution of this personalized medicine to patients when and where 
they  need  it  most  without  the  expense,  inconvenience,  and  potential  costly  failure  of  an  on-sight,  cryopreservation  apparatus.  Our 
customer  services  professionals  monitor  each  shipment  throughout  the  predetermined  process  including  the  shipment’s  return  to 

   
   
   
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
Cryoport where the Cryoport Express ® Shipper is cleaned, tested for quality assurance and then returned to inventory for reuse. 

28 

   
One of our distribution partners is Federal Express Corporation (“FedEx”). We have an agreement with FedEx to provide frozen 

shipping logistics services through the combination of our purpose-built proprietary technologies and turnkey management processes. FedEx 
markets and sells Cryoport’s services for frozen temperature-controlled cold chain transportation as its FedEx ® Deep Frozen Shipping Solution, 
on a non-exclusive basis and at its sole expense. During fiscal year 2013, the Company worked closely with FedEx to further align its sales 
efforts and accelerate penetration within FedEx’s life sciences customer base through improved processes, sales incentives, joint customer calls 
and more frequent communication at the sales and executive level. In addition, FedEx has developed a FedEx branded version of the Cryoportal 
TM software platform, which is “ powered by Cryoport, ” for use by FedEx and its customers giving them access to the full capabilities of our 
logistics management platform.  

In January 2013, we entered into a master agreement (“FedEx Agreement”) with FedEx renewing these services and providing FedEx with 
a non-exclusive license and right to use a customized version of our Cryoportal TM for the management of shipments made by FedEx customers. 
The FedEx Agreement became effective on January 1, 2013 and, unless sooner terminated as provided in the FedEx Agreement, expires on 
December 31, 2015.  

Pursuant to an agreement with DHL Express (USA), Inc. (“DHL”), DHL biotechnology and life science customers have direct access to 
our cloud-based order entry and tracking portal to order Cryoport Express ® Shippers and receive preferred DHL shipping rates. The agreement 
covers DHL shipping discounts that may be used to support our customers using our Cryoport Express ® Solutions. In connection with the 
agreement, we have integrated our proprietary Cryoportal TM to DHL’s tracking and billing systems to provide DHL biotechnology and life 
science customers with a seamless way (“ powered by Cryoport ”) of shipping their critical biological material worldwide.  

In December 2012, we signed an agreement with Pfizer Inc. relating to Zoetis Inc. (formerly the animal health business unit of Pfizer Inc.) 

pursuant to which we were engaged to manage frozen shipments of a key poultry vaccine. Under this arrangement, the Company is providing 
on-site logistics personnel and its logistics management platform, the Cryoportal TM , to manage shipments from the Zoetis manufacturing site in 
the United States to domestic customers as well as various international distribution centers. As part of our logistics management services, 
Cryoport is constantly analyzing shipping data and processes to further streamline Zoetis’ logistics, ensuring products arrive at their destinations 
in specified conditions, on-time and with the optimum uses of resources. The Company manages Zoetis’ total fleet of dewar flask shippers used 
for this purpose, including liquid nitrogen shippers. In July 2013, the agreement was amended to expand Cryoport’s scope to manage all logistics 
of Zoetis’ key frozen poultry vaccine to all Zoetis’ international distribution centers as well as all domestic shipments of this vaccine. In October 
2013, the agreement was further amended to further expand Cryoport’s services to include the logistics management for a second poultry 
vaccine.  

In February 2014, we entered into a services agreement with Liventa Bioscience, Inc. (“Liventa”), a commercial stage biotechnology 
company focused on cell-based, advanced biologics in the orthopedic industry. Under this agreement, Liventa will be using Cryoport Express ® 
Solutions for the logistics of its cell-based therapies requiring cryogenic temperatures and also provide Cryoport Express ® Solutions to other 
biologics suppliers within the orthopedic arena. The agreement combines Cryoport’s proprietary, purpose-built cold chain logistics solutions for 
cell-based and advanced biologic tissue forms with Liventa’s distribution capability to orthopedic care providers. The implementation of 
Cryoport’s solution will eliminate the need for expensive onsite cryogenic freezers for storage of cell-based orthopedic therapies. This will 
enable Liventa to better serve physicians at the point-of-care, whether at hospitals, clinics, pharmacies, family practices, surgery centers or 
orthopedic offices.  

We offer our solutions to companies in the life sciences industry and specific verticals including manufacturers of stem cells and cell lines, 

diagnostic laboratories, bio-pharmaceuticals, contract research organizations, in-vitro fertilization, cord blood, vaccines, tissue, animal 
husbandry, and other producers of commodities requiring reliable frozen solutions for logistics. These companies operate within heavily 
regulated environments and as such, changing vendors and distribution practices typically require a number of steps; which may include the 
audit of our facilities, review of our procedures, qualifying us as a vendor, and performing test shipments. This process can take up to nine 
months or longer to complete prior to a potential customer adopting one or more of the Cryoport Express ® Solutions.  

29 

   
   
   
    
   
   
   
  
Going Concern  

As reported in the Report of Independent Registered Public Accounting Firm to our March 31, 2014 and 2013 consolidated financial 

statements, we have incurred recurring losses and negative cash flows from operations since inception. These factors, among others, raise 
substantial doubt about our ability to continue as a going concern.  

We expect to continue to incur substantial additional operating losses from costs related to the commercialization of our Cryoport Express 

® Solutions and do not expect that revenues from operations will be sufficient to satisfy our funding requirements in the near term. We believe 
that our cash resources at March 31, 2014, and funds currently being raised through a preferred stock offering together with the revenues 
generated from our services will be sufficient to sustain our planned operations into the second quarter of fiscal year 2015; however, we must 
obtain additional capital to fund operations thereafter and for the achievement of sustained profitable operations. These factors raise substantial 
doubt about our ability to continue as a going concern. We are currently working on funding alternatives in order to secure sufficient operating 
capital to allow us to continue to operate as a going concern.  

Future capital requirements will depend upon many factors, including the success of our commercialization efforts and the level of 
customer adoption of our Cryoport Express ® Solutions as well as our ability to establish additional collaborative arrangements. We cannot make 
any assurances that the sales ramp will lead to achievement of sustained profitable operations or that any additional financing will be completed 
on a timely basis on acceptable terms or at all. Management’s inability to successfully achieve significant revenue increases or its cost reduction 
strategies or to complete any other financing will adversely impact our ability to continue as a going concern. To address this issue, the Company 
is seeking additional capitalization to properly fund our efforts to become a self-sustaining financially viable entity.  

While we increased revenue year-over-year by 142% to $2.7 million for the fiscal year ended March 31, 2014, our revenue is still 
significantly lower than our operating expenses during the year and we have no assurance of the level of future revenues. We incurred a net loss 
of $19.6 million and used cash of $4.4 million in our operating activities during the year ended March 31, 2014. We had negative working 
capital of $2.9 million, and had cash and cash equivalents of $369,600 at March 31, 2014.  

We are currently funding our operations through a preferred stock offering (see Note 15 in the accompanying consolidated financial 

statements) and plan to raise additional funds through additional debt or equity offerings to cover general working capital needs and sales and 
marketing initiatives to expand our customer base and increase sales. There is no assurance that funds can be secured or if these funds would 
allow us to continue our operations until more significant revenues can be generated or more funding can be secured. These matters raise 
substantial doubt about our ability to continue as a going concern.  

Liquidity and Capital Resources  

As of March 31, 2014, the Company had cash and cash equivalents of $369,600 and negative working capital of $2.9 million. As of 

March 31, 2013, the Company had cash and cash equivalents of $563,100 and negative working capital of $1.5 million. Historically, we have 
financed our operations primarily through sales of our debt and equity securities. From March 2005 through March 2014, we have received net 
proceeds of approximately $37.6 million from sales of our common stock and the issuance of promissory notes, warrants and debt.  

Net Cash Used In Operating Activities  

For the year ended March 31, 2014, we used $4.4 million of cash for operations primarily as a result of the net loss of $19.6 million offset 

by non-cash expenses of $15.4 million primarily comprised of debt conversion expense of $13.7 million, amortization of debt discount and 
deferred financing costs of $678,900, stock compensation expense of $678,100, depreciation and amortization of $311,600 which was partially 
offset by a change in fair value of derivative instruments of $20,800. Net operating losses decreased primarily as a result of increase in net 
revenues. Also contributing to the cash impact of our net operating loss (excluding non-cash items) was an increase in accounts receivable of 
$323,600.  

Net Cash Used In Investing Activities  

Net cash used in investing activities totaled $138,900 during the year ended March 31, 2014 and was attributable to the purchase of 

property and equipment, primarily the increase in Cryoport Express ® High Volume Shipper to meet expected customer demand.  

30 

   
   
   
   
    
   
   
   
   
   
   
   
   
  
Net Cash Provided By Financing Activities  

Net cash provided by financing activities totaled $4.3 million during the year ended March 31, 2014, which resulted from proceeds from 

the issuance of convertible debt of $4.6 million and proceeds from the exercise of stock options and warrants of $326,900, partially offset by the 
payment of financing costs of $463,200 and the repayment of related party notes payable of $96,000.  

As discussed in Note 1 of the accompanying consolidated financial statements, there exists substantial doubt regarding the Company’s 

ability to continue as a going concern. The Company issued unsecured convertible promissory notes in principal amount of $1.8 million in the 
third and fourth quarters of fiscal 2014. In addition, the Company is currently raising funds through a preferred stock offering as further 
described in Note 15 in the accompanying consolidated financial statements. The funds raised are being used for working capital purposes and to 
continue our sales efforts to advance the Company’s commercialization of the Cryoport Express ® Solutions. However, the Company’s 
management recognizes that the Company will need to obtain additional capital to fund its operations until sustained profitable operations are 
achieved. Management is currently working on such funding alternatives in order to secure sufficient operating capital through the end of fiscal 
year 2015. In addition, management will continue to review its operations for further cost reductions to extend the time that the Company can 
operate with its current cash on hand and additional bridge financing and to utilize third parties for services such as its international recycling 
and refurbishment centers to provide for greater flexibility in aligning operational expenses with the changes in sales volumes.  

Results of Operations  

Results of Operations for Fiscal 2014 Compared to Fiscal 2013  

The following table summarizes certain information derived from our consolidated statements of operations:  

Year Ended March 31, 

2014 

2013 

$ Change       % Change    

($ in 000’s) 

Revenues 
Cost of revenues 

   $ 

2,660      $ 
(2,223 )      

1,101      $ 
(1,588 )      

1,559        
(635 )      

Gross margin (loss) 
Selling, general and administrative 
Research and development 
Debt conversion expense 
Interest expense 
Change in fair value of derivative liabilities 
Other expense 
Provision for income taxes 

437        
(5,106 )      
(409 )      
(13,714 )      
(784 )      
21        
(8 )      
(2 )      

(487 )      
(5,412 )      
(425 )      
—       
(72 )      
16        
—       
(2 )      

924        
306        
16        
(13,714 )      
(712 )      
5        
(8 )      
—       

141.7 % 
40.0 % 

189.7 % 
(5.6 )% 
(3.8 )% 
100 % 
976.6 % 
26.5 % 
100 % 
—  

Net loss 

   $ 

(19,565 )    $ 

(6,382 )    $ 

(13,183 )      

206.6 % 

Revenues . We generated revenues from customers in all of our target life sciences markets, such as biotech and diagnostic companies, 

pharmaceutical companies, central laboratories, contract research organizations, the reproductive medicine market/in vitro fertilization market, 
and research institutions. Net revenues were $2.7 million for the year ended March 31, 2014, as compared to $1.1 million for the year ended 
March 31, 2013. This $1.6 million or 142% increase is primarily driven by the ramp up and expansion of logistics services provided to Zoetis, an 
increase in revenues in the reproductive medicine/in vitro fertilization market and an overall increase in both, the number of customers utilizing 
our services and frequency of shipments compared to the prior year. Our revenues from Zoetis increased to $820,600 for the year ended March 
31, 2014 from $62,300 during the prior year. This reflects the successful implementation and expansion of our integrated model with Zoetis, 
which commenced in February of 2013, whereby we manage the cryogenic shipments of a certain vaccine, both domestically and globally, and 
in October of 2013 expanded our services to include the logistics management for a second vaccine. The increase in revenues in the reproductive 
medicine/in vitro fertilization market was particularly strong, with revenues increasing from $238,000 to $614,000, an increase of $376,000 or 
158%. This is partially the result of targeted telemarketing activities and email marketing campaigns to broaden the awareness of our solution in 
this space.  

Gross margin and cost of revenues . Gross margins for the year ended March 31, 2014 was 16.4% of revenues, as compared to a gross 

loss of 44.3% of revenues for the prior year. The increase in gross margin is primarily due to the increase in net revenue combined with a 
reduction in freight as a percentage of revenues and a decrease of fixed manufacturing costs. Cost of revenues for the year ended March 31, 2014 
was 83.6% of revenues, as compared to 144.3% of revenues for the prior year. Our cost of revenues are primarily comprised of freight charges, 
payroll and related expenses related to our operations center in California, third-party charges for our European and Asian operations centers in 
Holland and Singapore, depreciation expenses of our Cryoport Express® Shippers and supplies and consumables used for our solutions. The 
increase in cost of revenues is primarily due to freight charges from the growth in shipments.  

31 

   
   
   
   
   
   
   
   
   
  
  
  
    
  
    
  
  
  
  
    
    
  
  
    
  
    
  
  
  
  
      
      
      
    
     
  
     
         
         
         
    
     
     
     
     
     
     
     
     
  
     
         
         
         
    
Selling, general and administrative expenses . Selling, general and administrative expenses decreased $306,000, or 5.6% for the year 

ended March 31, 2014 as compared to the prior year. This decrease is primarily related to a severance payment of approximately $180,000 paid 
to the former Chief Executive Officer in April 2012 and a decrease in board of director stock-based compensation. Partially offsetting these 
decreases is an increase in compensation related to replacement of the Chief Executive Officer and an increase in expenses related to sales and 
marketing activities compared to previous year.  

Research and development expenses . Research and development expenses decreased $16,000 or 3.8% for the year ended March 31, 

2014, as compared to the prior year. Our research and development efforts are focused on continually improving the features of the Cryoport 
Express ® Solutions including the Company’s cloud-based logistics management platform, the Cryoportal TM , the Cryoport Express ®  Shippers 
and development of additional accessories to facilitate the efficient shipment of life science commodities using our solution. We use an outside 
software development company and other third parties to provide some of these services. Research and development expenses to date have 
consisted primarily of costs associated with the continually improving the features of the Cryoport Express ® Solution including the web based 
customer service portal and the Cryoport Express ® Shippers. Further, these efforts are expected to lead to the introduction of shippers of varying 
sizes based on market requirements, constructed of lower cost materials and utilizing high volume manufacturing methods that will make it 
practical to provide the cryogenic packages offered by the Cryoport Express ® Solution. Other research and development effort has been directed 
toward improvements to the liquid nitrogen retention system to render it more reliable in the general shipping environment and to the design of 
the outer packaging. Alternative phase change materials in place of liquid nitrogen may be used to increase the potential markets these shippers 
can serve such as ambient and 2°-8°C markets.  

Debt conversion expense. Debt conversion expense for the year ended March 31, 2014 of $13.7 million was related to the induced 
conversion of $4,127,200 of aggregate principal and accrued interest from the convertible bridge notes into shares of common stock and 
warrants. Debt conversion expense represents the fair value of the securities transferred in excess of the fair value of the securities issuable upon 
the original conversion terms of the bridge notes.  The Company calculated the fair value of the common stock issued by using the closing price 
of the stock on the date of issuance.  The fair value of the warrants was calculated using the Black-Scholes option pricing model.  

Interest expense . Interest expense increased $712,000 for the year ended March 31, 2014, as compared to the prior year. Interest expense 

for the year ended March 31, 2014 included amortization of the debt discount and deferred financing fees of approximately $678,900, interest 
expense on our bridge notes of approximately $71,600 and accrued interest on our related party notes payable of approximately $36,500. Interest 
expense for the year ended March 31, 2013 included amortization of the debt discount of approximately $17,500, interest expense on our 
convertible debentures of approximately $9,900 and accrued interest on our related party notes payable of approximately $42,200.  

Change in fair value of derivative liabilities . The gain for the year ended March 31, 2014 was the result of a decrease in the value of our 

warrant derivatives, due primarily to a decrease in our stock price.  

Other expense, net . The other expense, net for the year ended March 31, 2014 is primarily due to administrative charges and foreign 

exchange losses on accounts receivable and payable invoices.  

Off-Balance Sheet Arrangements  

We do not have any off balance sheet arrangements within the meaning of Item 303(a)(4) of Regulation S-K.  

Contractual Obligations  

The  following  table  summarizes  our  contractual  obligations  as  of  March 31,  2014,  and  the  effects  such  obligations  are  expected  to  have  on 
liquidity and cash flow in future periods ($ in ‘000’s):  

Total  

Less than  
1 Year  

1-3 Years       

4-5 Years       

After  
5 Years  

Contractual obligations 
Operating lease obligations (1) 
Bridge notes (2) 
Other long-term obligations (3) 

   $ 

220      $ 

193      $ 

1,807     
1,358     

1,807     
1,358     

27      $ 
—    
—    

Total 

   $ 

3,385      $ 

3,358      $ 

27      $ 

—     $ 
—    
—    

—

     $ 

—  
—  
—  

—  

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(1)  The  operating  lease  obligations  are  primarily  related  to  the  facility  lease  for  our  principal  executive  office  in  Lake  Forest,  California 

expiring June 30, 2015; and for our San Diego, California facility expiring December 31, 2014. 

(2)  Bridge notes represent unsecured convertible promissory notes and accrued interest at 5% per annum which were issued in the third and 
fourth quarter of 2014 to certain accredited investors pursuant to the terms of subscription agreements and letters of investment intent. All 
principal and accrued interest is due June 30, 2014. 

(3)  Other  long-term  obligations  represent  outstanding  unsecured  indebtedness  and  accrued  interest  owed  to  four  related  parties  which  bear 
interest at the rate of 6% per annum. Any unpaid principal and accrued interest is due at maturity on various dates through March 1, 2015. 

Impact of Inflation  

From time to time, Cryoport experiences price increases from third party manufacturers and these increases cannot always be passed on to 
Cryoport’s customers. While these price increases have not had a material impact on Cryoport’s historical operations or profitability in the past, 
they could affect revenues in the future.  

Critical Accounting Policies and Estimates  

Our discussion and analysis of our consolidated financial condition and results of operations are based upon our consolidated financial 
statements, which have been prepared in conformity with accounting principles generally accepted in the U.S., or GAAP. The preparation of 
these consolidated financial statements requires us to make estimates and assumptions that affect the reported amounts of assets, liabilities, 
revenues and expenses, and related disclosure of contingent assets and liabilities reported in our consolidated financial statements. The 
estimation process requires assumptions to be made about future events and conditions, and is consequently inherently subjective and uncertain. 
Actual results could differ materially from our estimates.  

The  SEC  defines  critical  accounting  policies  as  those  that  are,  in  management’s  view,  most  important  to  the  portrayal  of  our  financial 
condition and results of operations and most demanding of our judgment. We consider the following policies to be critical to an understanding of 
our consolidated financial statements and the uncertainties associated with the complex judgments made by us that could impact our results of 
operations, financial position and cash flows. See Note 2: “ Summary of Significant Accounting Policies ” of our accompanying consolidated 
financial statements for a description of our critical accounting policies and estimates.  

New Accounting Pronouncements  

See  Note  2:  “  Recent  Accounting  Pronouncements  ”  of  our  accompanying  consolidated  financial  statements  for  a  description  of  recent 
accounting pronouncements that may have a significant impact on our financial reporting and our expectations of their impact on our results of 
operations and financial condition.  

Item 7A.  Quantitative and Qualitative Disclosures About Market Risk 

Changes in United States interest rates would affect the interest earned on our cash and cash equivalents.  

Based on our overall cash and cash equivalents interest rate exposure at March 31, 2014, a near-term change in interest rates, based on 

historical movements, would not have a material adverse effect on our financial position or results of operations.  

We have operated primarily in the United States. Accordingly, we have not had any significant exposure to foreign currency rate 

fluctuations.  

Item 8. 

Financial Statements and Supplementary Data 

Our annual consolidated financial statements are included in Item 15 of this report.  

Item 9. 

Changes in and Disagreements with Accountants on Accounting and Financial Disclosure 

None.  

Item 9A.  Controls and Procedures 

33 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
    
  
    
  
(a) Evaluation of Disclosure Controls and Procedures  

The term “disclosure controls and procedures” (defined in Rule 13a-15(e) under the Securities and Exchange Act of 1934 (the “Exchange 

Act”) refers to the controls and other procedures of a company that are designed to ensure that information required to be disclosed by a 
company in the reports that it files under the Exchange Act is recorded, processed, summarized and reported within the required time periods. 
Under the supervision and with the participation of our management, including our Chief Executive Officer and Chief Financial Officer, we have 
conducted an evaluation of the effectiveness of the design and operation of our disclosure controls and procedures, as of March 31, 2014. Based 
on this evaluation, our Chief Executive Officer and Chief Financial Officer concluded that our disclosure controls and procedures were effective 
as of March 31, 2014 to ensure the timely disclosure of required information in our Securities and Exchange Commission filings.  

Because of inherent limitations, internal control over financial reporting may not prevent or detect misstatements. In addition, the design of 
any system of control is based upon certain assumptions about the likelihood of future events, and there can be no assurance that any design will 
succeed in achieving its stated goals under all future events, no matter how remote. Accordingly, even effective internal control over financial 
reporting can only provide reasonable assurance of achieving their control objectives.  

(b) Management’s Report on Internal Control Over Financial Reporting .  

Management’s Report on Internal Control Over Financial Reporting which appears on the following page is incorporated herein by this 

reference.  

(c) Changes in internal control over financial reporting  

During  the  quarter  ended  March  31,  2014,  there  were  no  changes  in  our  internal  control  over  financial  reporting  that  have  materially 

affected, or are reasonably likely to materially affect, our internal control over financial reporting.  

Item 9B.  Other Information 

None.  

34 

   
   
   
   
   
   
   
   
   
   
  
CRYOPORT, INC.  
MANAGEMENT’S REPORT ON  
INTERNAL CONTROL OVER FINANCIAL REPORTING  

The management of the Company is responsible for establishing and maintaining effective internal control over financial reporting and 
for the assessment of the effectiveness of internal control over financial reporting. The Company’s internal control over financial reporting is 
a process designed, as defined in Rule 13a-15(f) under the Securities and Exchange Act of 1934, to provide reasonable assurance regarding 
the reliability of financial reporting and the preparation of consolidated financial statements for external purposes in accordance with 
accounting principles generally accepted in the United States of America.  

The Company’s internal control over financial reporting is supported by written policies and procedures that:  

• 

• 

• 

pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of 
the Company’s assets; 

provide  reasonable  assurance  that  transactions  are  recorded  as  necessary  to  permit  preparation  of  consolidated  financial 
statements in accordance with accounting principles generally accepted in the United States of America, and that receipts and 
expenditures  of  the  Company  are  being  made  only  in  accordance  with  authorizations  of  the  Company’s  management  and 
directors; and 

provide reasonable  assurance regarding  prevention  or  timely  detection  of  unauthorized acquisition, use  or  disposition  of  the 
Company’s assets that could have a material effect on the consolidated financial statements. 

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Projections of any 
evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or 
that the degree of compliance with the policies or procedures may deteriorate.  

In connection with the preparation of the Company’s annual consolidated financial statements, management of the Company has 
undertaken an assessment of the effectiveness of the Company’s internal control over financial reporting based on criteria established in 
Internal Control — Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (“the COSO 
Framework”). Management’s assessment included an evaluation of the design of the Company’s internal control over financial reporting and 
testing of the operational effectiveness of the Company’s internal control over financial reporting.  

Based on this assessment, management has concluded that the Company’s internal control over financial reporting was effective as of 

March 31, 2014.  

By: 

By: 

/s/ JERRELL W. SHELTON 
Jerrell W. Shelton, 
Chief Executive Officer and Director 

/s/ ROBERT STEFANOVICH 
Robert Stefanovich, 
Chief Financial Officer 

June 25, 2014  

35 

   
   
   
   
   
    
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
  
  
  
Item 10. 

PART III  
Directors, Executive Officers and Corporate Governance 

The  information  required  under  this  item  is  incorporated  by  reference  from  our  definitive  proxy  statement  related  to  our  2014  Annual 

Meeting of Stockholders, or the Proxy Statement, to be filed pursuant to Regulation 14A, on or before July 31, 2014.  

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION  

None.  

Item 11. 

Executive Compensation 

Executive Officers of the Company  

The Company’s current executive officers are as follows:  

Jerrell W. Shelton, age 68, became President and Chief Executive Officer of the Company on November 5, 2012. He served on the 
Board of Directors and standing committees of Solera Holdings, Inc. from April 2007 through November 2011. From June 2004 to May 
2006, Mr. Shelton was the Chairman and CEO of Wellness, Inc., a provider of advanced, integrated hospital and clinical environments. Prior 
to that, he served as CEO of IBM’s WebFountain. From October 1998 to October 1999, Mr. Shelton was Chairman, President and CEO of 
NDC Holdings II, Inc. Between October 1996 and July 1998, he was President and CEO of Continental Graphics Holdings, Inc. and from 
October 1991 to July 1996, Mr. Shelton served as President and CEO of Thomson Business Information Group. Mr. Shelton has a B.S. in 
Business Administration from the University of Tennessee and an M.B.A. from Harvard University. Mr. Shelton currently serves on the 
Advisory Board of Directors and the Nominating and Stewardship committee of the Smithsonian Institution Libraries.  

Robert S. Stefanovich, age 49, became Chief Financial Officer, Treasurer and Corporate Secretary for the Company on June 27, 2011 
following the Company’s filing of its Form 10–K for the fiscal year ended March 31, 2011. From June 15, 2012 to November 4, 2012, Mr. 
Stefanovich served as the Principal Executive Officer of the Company. From November 2007 through March 2011, Mr. Stefanovich served 
as Chief Financial Officer of Novalar Pharmaceuticals, Inc., a venture-backed specialty pharmaceutical company. Prior to that, he held 
several senior positions, including interim Chief Financial Officer of Xcorporeal, Inc., a publicly traded medical device company, Executive 
Vice President and Chief Financial Officer of Artemis International Solutions Corporation, a publicly traded software company, Chief 
Financial Officer and Secretary of Aethlon Medical Inc., a publicly traded medical device company and Vice President of Administration at 
SAIC, a Fortune 500 company. Mr. Stefanovich also served as a member of the Software Advisory Group and an Audit Manager with Price 
Waterhouse LLP’s (now PricewaterhouseCoopers) hi-tech practice in San Jose, CA and Frankfurt, Germany. He currently also serves as a 
board member of Project InVision International, a provider of business performance improvement solutions. He received his Masters of 
Business Administration and Engineering from University of Darmstadt, Germany.  

The following table contains information with respect to the compensation for the fiscal years ended March 31, 2014 and 2013 of our 
chief executive officer, chief financial officer and former chief executive officer. We refer to the executive officers identified in this table as 
our “Named Executive Officers.”  

SUMMARY COMPENSATION TABLE  

Name and Principal Position 
Jerrell W. Shelton 

President and Chief Executive Officer     

Robert S. Stefanovich 

Chief Financial Officer 

Larry G. Stambaugh 

Former President, Chief Executive  
Officer and Chairman 

Bonus  
($) 

Fiscal  
Year 

2014       
2013       
2014       
2013       
2014       
2013 

Salary (1)  
($) 
300,000 (4)     
122,885 (9)     
225,000 (4)     
225,000 (4)     
—  
6,923 (2) 

36 

Option  
Awards (5)  
($) 
930,358 (3)     
295,380 (7)     
201,028 (6)     
40,652 (6)     
—  
—

—      
—      
—      
—      
—      
—

All Other  
Compensation 

Total  
Compensation 

($) 

—  
4,409 (8)      
—  
—  
—  
241,115 (10) 

($) 
1,230,358   
422,674   
426,028   
265,652   
—  
248,038 

   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
    
  
  
    
  
  
 
  
  
 
  
    
    
    
    
    
    
    
    
    
    
    
      
    
      
  
    
    
  
(1) 
(2) 

(3) 

(4) 
(5) 

(6) 

(7) 

(8) 

This column represents salary as of the last payroll period prior to or immediately after March 31 of each fiscal year. 
On  August  21,  2009,  the  Compensation  Committee  approved  an  employment  agreement  with  Mr.  Stambaugh  which  had  an  effective 
commencement date of August 1, 2009, the details of which are described below. $57,794 and $360,000 were paid to Mr. Stambaugh in 
fiscal 2013 and 2012, respectively, per the terms of the employment agreement. Mr. Stambaugh resigned as President, Chief Executive 
Officer and Chairman on April 5, 2012. 
This amount represents the fair value of all options granted to Mr. Shelton as compensation for services as a director and officer of the 
Company  during  fiscal  2014. Based on the  recommendation of the  Compensation  Committee  and  approval  by  the Board, on June  28, 
2013, Mr.  Shelton was  granted  an  option  to  purchase  3,902,507  shares  of  common  stock  in connection  with  his  engagement as  Chief 
Executive Officer of the Company. 
This amount represents the annual base salary paid. 
This  column represents the  total grant date fair  value  of all stock  options granted  in fiscal 2014 and the Company’s fiscal  year  ended 
March 31, 2013. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeitures related to service-based vesting 
conditions.  For  information  on  the  valuation  assumptions  with  respect  to  the  grants  made  in  fiscal  2014  and  2013,  refer  to  Note  2  “
Summary of Significant Accounting Policies ” in the accompanying consolidated financial statements. 
This amount represents the fair value of all options granted to Mr. Stefanovich as compensation for services during fiscal 2014 and 2013. 
Based on the recommendation of the Compensation Committee and approval by the Board, on June 28, 2013 and August 3, 2012 Mr. 
Stefanovich  was  granted  an  option  to  purchase  839,016  and  100,000  shares  of  common  stock,  respectively.  The  exercise  price  of  the 
options are equal to the fair value of the Company’s stock as of the grant date. 
This amount represents the fair value of all options granted to Mr. Shelton as compensation for services as a director and officer of the 
Company during fiscal 2013. Based on the recommendation of the Board, on October 22, 2012, Mr. Shelton was granted an option to 
purchase 100,000 shares of the Company’s common stock upon joining the Board. Based on the recommendation of the Compensation 
Committee  and  approval  by  the  Board,  on  November  5,  2012,  Mr.  Shelton  was  granted  an  option  to  purchase  1,650,000  shares  of 
common stock in connection with his engagement as Chief Executive Officer of the Company 
This amount represents board fees paid to Mr. Shelton as compensation for services as a director of the Company during fiscal 2013 prior 
to becoming Chief Executive Officer of the Company. 
Reflects a pro-rated salary for Mr. Shelton who began employment with the Company on November 5, 2012. 

(9) 
(10)  Amount  represents  $180,000  severance  payment,  $50,871  personal  time  off  payout  and  $10,244  COBRA  reimbursements  to  Mr. 

Stambaugh per the terms of his separation agreement. 

Narrative Disclosure to Summary Compensation Table  

Employment Contracts   

Jerrell W. Shelton  

On November 5, 2012, the Company entered into an employment agreement (the “Initial Agreement”) with Mr. Shelton with respect to 

his employment as President and Chief Executive Officer. The Initial Agreement provided a term of six months. The Initial Agreement 
provided an initial annual base salary of $300,000 during the Term.  

In addition, on the date of the Initial Agreement, Mr. Shelton was awarded two options giving him the right to acquire an aggregate of 

1,650,000 shares of the Company’s common stock at an exercise price equal to the closing price of the Company’s common stock on the date 
of the Agreement, or $0.20 per share. The aggregate number of shares was determined by dividing $350,000 by the closing price of the 
Company’s common stock on the date of the Agreement, or $0.20 per share, and subtracting 100,000 shares, which is the number of shares of 
common stock that Mr. Shelton was given the right to purchase pursuant to the option that was issued to him in connection with his 
appointment to the Board of Directors on October 22, 2012. The first option issued in connection with the Agreement was issued under the 
Company’s 2011 Stock Incentive Plan and provides Mr. Shelton the right to purchase 650,000 shares of the common stock of the Company, 
which is the maximum that may be awarded to Mr. Shelton in this fiscal year under such plan. Mr. Shelton subsequently exercised 650,000 of 
these shares in May and November 2013. The second option provided Mr. Shelton the right to purchase 1,000,000 shares of common stock of 
the Company and was granted outside of the Company’s incentive plans. The options vest in six equal monthly installments during the Term 
and expire at the earlier of (a) ten years from the date of the Agreement, and (b) five (5) years from the date of the resignation and/or removal 
of the Mr. Shelton as a member of the Board of Directors of the Company.  

On June 28, 2013, after the expiration of the Initial Agreement, the Company entered into a new employment agreement (the 

“Agreement”) with Mr. Shelton with respect to his employment as President and Chief Executive Officer. The Agreement is effective 
through May 14, 2017 (the “Term”).  

The Agreement provides an initial annual base salary of $300,000 during the Term. In addition, on the date of the Agreement, Mr. 
Shelton was awarded options giving him the right to acquire an aggregate of 3,902,507 shares of the Company’s common stock at an exercise 
price equal to the closing price of the Company’s common stock on the date of the Agreement, or $0.27 per share, and such options were 
granted outside of the Company’s incentive plans. The option vests immediately with respect to 162,604 shares and the remaining right to 
purchase the remaining shares vests in equal monthly installments on the fifth day of each month for forty six months beginning on July 5, 
2013 and ending on May 5, 2017. Provided that such vesting will be accelerated on the date that the Company files a Form 10-Q or Form 10-
K indicating an income from operations for the Company in two consecutive fiscal quarters and immediately in the event of a change of 
control of the Company.  

   
   
   
   
   
   
   
   
   
  
37 

The options expire at the earlier of (a) ten years from the date of the Agreement, and (b) twenty four (24) months from the date of the 

resignation and/or removal of the Mr. Shelton as Chief Executive Officer of the Company.  

Mr. Shelton has agreed during the Term and for a period of one year following the termination of the Agreement, not to solicit, induce, 

entice or attempt to solicit, induce, or entice any employee of the Company to leave employment with the Company. Payments due to 
Mr. Shelton upon a termination of his employment agreement are described below.  

Robert S. Stefanovich  

Although the Company does not have a written employment agreement with Mr. Stefanovich, pursuant to the terms of his offer letter, 
the Company has agreed to pay Mr. Stefanovich an annual base salary of $225,000 per year. In addition, he is eligible for an incentive bonus 
targeted at 25% of his annual base salary. Mr. Stefanovich is eligible to participate in all employee benefits plans or arrangements which may 
be offered by the Company during the term of his agreement. The Company shall pay the cost of Mr. Stefanovich’s health insurance coverage 
in accordance with the Company’s plans and policies while he is an employee of the Company. Mr. Stefanovich is also eligible for fifteen 
(15) paid time off days a year, and is entitled to receive fringe benefits ordinarily and customarily provided by the Company to its senior 
officers. Payments due to Mr. Stefanovich upon a termination of his employment agreement with the Company are described below.  

Larry G. Stambaugh (former President and Chief Executive Officer)  

On August 21, 2009, the Compensation Committee approved an employment agreement with Mr. Stambaugh, the Company’s former 

Chief Executive Officer, President and Chairman, which commenced effective as of August 1, 2009 and continued in effect until April 5, 
2012 (the “Stambaugh Employment Agreement”), the date of Mr. Stambaugh’s resignation. Pursuant to the terms of the Stambaugh 
Employment Agreement, Mr. Stambaugh was paid an annual base salary of $360,000. In connection with Mr. Stambaugh’s resignation as 
Chief Executive Officer and Chairman of the Board, the Company paid Mr. Stambaugh a lump sum severance payment of $180,000 and 
extended the exercise period of two stock options granted to Mr. Stambaugh on September 10, 2010, with exercise prices of $0.66 per share 
until April 5, 2017 with respect to those underlying shares of common stock vested as of April 5, 2012, which amount to 362,232 and 
210,000 shares of the Company’s common stock, respectively.  

The Company has no other employment agreements with executive officers of the Company as of March 31, 2014.  

OUTSTANDING EQUITY AWARDS AT FISCAL YEAR END 2014  

The following table shows information regarding unexercised stock options held by our Named Executive Officers as of fiscal year ended 

March 31, 2014:  

Equity  
 Incentive  
 Plan Awards 

Name 
Jerrell W. Shelton 

Robert Stefanovich 

Larry Stambaugh 

Number of  
 Securities  
 Underlying 
Unexercised 

 Options  
 (#)  
 Exercisable   

100,000 (1)     
     1,000,000 (2)     
894,324 (3)     
78,125 (4)     
—(5)     
22,500 (6)     
157,316 (7)     
362,232 (8)     
210,000 (9)     

Number of  
 Securities  
 Underlying  
 Unexercised  
 Options  
 (#)  
 Unexercisable     
—      
—      
—      
—      
—      
—      
—      
—      
—      

 Number of  
 Securities  
 Underlying  
 Unexercised 
 Unearned  
 Options  
 (#) 

  Option  
 Exercise  
 Price  
 ($) 

—  
—  

  $ 
  $ 
3,008,183 (3)   $ 
46,875 (4)   $ 
40,000 (5)   $ 
37,500 (6)   $ 
681,700 (7)   $ 
—  
  $ 
—(9)   $ 

0.19     
0.20     
0.27     
0.86     
0.43     
0.43     
0.27     
0.66     
0.66     

Option  
 Expiration  
 Date 
10/21/22   
11/4/22   
6/27/23   
6/19/21   
8/2/22   
8/2/22   
6/27/23   

4/5/17 (10) 
4/5/17 (10) 

38 

   
    
   
   
   
   
   
   
   
   
   
  
  
 
  
 
  
  
    
  
    
  
  
    
    
  
    
  
    
  
    
    
  
    
(1) 

(2) 

(3) 

(4) 

(5) 

(6) 

(7) 

(8) 

(9) 

(10) 

Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Shelton was granted an option to 
purchase 100,000 shares of common stock exercisable at $0.19 per share on October 22, 2012 upon joining the board of directors. 
Options vests in twelve equal monthly installments. The exercise price for shares of common stock pursuant to the options is equal to the 
fair value of the Company’s stock as of the grant date. 
Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Shelton was granted an option to 
purchase 1,650,000 shares of common stock exercisable at $0.20 per share on November 5, 2012, which vests in six equal monthly 
installments. 650,000 of these options were issued under the 2011 stock option plan and exercised in May and November 2013 and 
1,000,000 were issued outside of a plan. The exercise price for shares of common stock pursuant to the option is equal to the fair value of 
the Company’s stock as of the grant date. 
Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Shelton was granted an option to 
purchase 3,902,507 shares of common stock exercisable at $0.27 per share on June 28, 2013. The option vests 2/48 th immediately with 
the remainder vesting 1/48 th per month for 46 months. The exercise price for the shares of common stock pursuant to the option is equal 
to the fair value of the Company’s stock on the date of grant. 
Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Stefanovich was granted an option to 
purchase 125,000 shares of common stock exercisable at $0.86 per share on June 20, 2011. The option vests in six month installments 
over a four year period. The exercise price for the shares of common stock pursuant to the option is equal to the fair value of the 
Company’s stock on the date of grant. 
Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Stefanovich was granted an option to 
purchase 40,000 shares of common stock exercisable at $0.43 per share on August 3, 2012. The option vests based on certain 
performance criteria. The exercise price for the shares of common stock pursuant to the option is equal to the fair value of the Company’s 
stock on the date of grant 
Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Stefanovich was granted an option to 
purchase 60,000 shares of common stock exercisable at $0.43 per share on August 3, 2012. The option vests in six month installments 
over a four year period. The exercise price for the shares of common stock pursuant to the option is equal to the fair value of the 
Company’s stock on the date of grant 
Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Stefanovich was granted an option to 
purchase 839,016 shares of common stock exercisable at $0.27 per share on June 28, 2013. The options vest in equal monthly 
installments over four years.  The exercise price for the shares of common stock pursuant to the option is equal to the fair value of the 
Company’s stock on the date of grant. 
Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Stambaugh was granted an option to 
purchase 362,232 shares of common stock exercisable at $0.66 per share on September 15, 2010, in lieu of payment of his fiscal year 
2010 cash bonus of $216,000. The option was fully vested at date of grant. The exercise price for shares of common stock pursuant to the 
option is equal to the fair value of the Company’s stock as of the grant date. 
Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Stambaugh was granted an option to 
purchase 420,000 shares of common stock exercisable at $0.66 per share on September 15, 2010. The right to exercise the stock option 
vested as to 25% of the underlying shares of common stock upon grant, with the remaining underlying shares vesting in equal 
installments on the first, second and third anniversary of the grant date. The exercise price for shares of common stock pursuant to the 
option is equal to the fair value of the Company’s stock as of the grant date. 
In connection with Mr. Stambaugh’s resignation as Chief Executive Officer and Chairman of the Board, which was effective on April 5, 
2012, the Company extended the exercise period of two stock options granted to Mr. Stambaugh on September 10, 2010, with exercise 
prices of $0.66 per share until April 5, 2017 with respect to those underlying shares of common stock vested as of April 5, 2012, which 
amount to 362,232 and 210,000 shares of the Company’s common stock, respectively. 

Potential Payments On Termination Or Change In Control  

Pursuant to Mr. Shelton’s employment agreement, if Mr. Shelton terminates the Agreement, dies, or is terminated for “Cause” (as 

defined in the agreement), he will be entitled to all compensation and benefits that he earned through the date of termination. If he is 
terminated for Cause, the Company may, to the extent allowed by law set off losses, fines or damages that he has caused as a result of his 
misconduct. If he is terminated “without cause” (as defined in the agreement), he will be entitled to a continuation of his base salary for three 
months following termination and one half of unvested options as of date of termination shall become fully vested. In the event the Company 
terminates his employment, except if for “Cause” (as defined in the agreement), within twelve (12) months after a Change in Control (as 
defined in the Cryoport, Inc. 2011 Stock Incentive Plan), then, Mr. Shelton will be entitled to: (i) the continuation of his base salary for 
twelve (12) months following the date of termination, which shall be paid in accordance with the Company’s ordinary payroll practices in 
effect from time to time, and which shall begin on the first payroll period immediately following the date on which the general release and 
waiver becomes irrevocable; and (ii) all options previously granted to Mr. Shelton will become fully vested and exercisable as of the date of 
termination.  

39 

   
   
   
   
  
Pursuant to Mr. Stefanovich’s employment offer, in the event that Mr. Stefanovich’s employment with the Company is terminated as a 
result of a “change of control,” as is defined in the Company’s 2009 Stock Incentive Plan, he will be entitled to receive a severance payment 
equal to twelve months of his base salary, continuation of health benefits for a period of twelve months, and the unvested portion of his stock 
option grants immediately shall vest in full. Separately, in the event his employment is terminated by the Company for reasons other than 
cause, Mr. Stefanovich will be entitled to receive a severance payment equal to six months of his base salary plus continuation of health 
benefits for a period of six months.  

In connection with Mr. Stambaugh’s resignation as Chief Executive Officer and Chairman of the Board, which was effective on April 

5, 2012, the Company paid Mr. Stambaugh a lump sum severance payment of $180,000 and extended the exercise period of two stock 
options granted to Mr. Stambaugh on September 10, 2010, with exercise prices of $0.66 per share until April 5, 2017 with respect to those 
underlying shares of common stock vested as of April 5, 2012, which amount to 362,232 and 210,000 shares of the Company’s common 
stock, respectively.  

The 2002 Plan, 2009 Plan and 2011 Plan each provide that in the event of a “change of control,” the applicable option agreement may 

provide that such options or shares will become fully vested and may be immediately exercised by the person who holds the option, at the 
discretion of the board.  

The Company does not provide any additional payments to named executive officers upon their resignation, termination, retirement, or 

upon a change of control.  

Change in Control Agreements    

There are no understandings, arrangements or agreements known by management at this time which would result in a change in control 

of the Company or any subsidiary.  

DIRECTOR COMPENSATION  

Compensation for the Board is governed by the Company’s Compensation Committee. Effective August 21, 2009 through May 2, 2012 

the fees payable to non-employee directors were set at a flat fee of $15,000 per quarter with no additional fees payable for committee 
membership or serving as chairman of a committee. Effective May 3, 2012, the cash compensation that each non-employee director is paid is 
$40,000 annually, except for the non-employee Chairman of the Board who is paid $56,000 annually. In addition, each non-employee 
director who serves as Chairman of one or more Board Committees will be paid additional cash compensation of $8,000 annually for all 
Committee Chairmanships.  

Effective May 3, 2012, each non-employee director is awarded a stock option to purchase 50,000 shares of the Company’s common 
stock on the date of the Company’s annual meeting of stockholders, except for the non-employee Chairman of the Board who is awarded a 
stock option to purchase 80,000 shares of the Company’s common stock. In addition, each new non-employee director will be granted a stock 
option to purchase 100,000 shares of the Company’s common stock upon joining the Board.  

On May 3, 2012, Mr. Michelin was granted options to purchase a total of 60,000 shares of the Company’s common stock with an 
exercise price of $0.44 per share which vested on September 22, 2012 for his service as a director, Chairman of the Audit Committee, and as 
a member of the Compensation Committee and the Nomination and Governance Committee during fiscal 2012 and fiscal 2013 and Lead 
Independent Director during fiscal 2012. The options to purchase a total of 35,000 shares were issued in connection with the services he 
provided during fiscal 2012.  

On May 3, 2012, Mr. Wasserman was granted options to purchase a total of 138,356 shares of the Company’s common stock with an 

exercise price of $0.44 per share which vested on March 29, 2013 for his service as a director, Chairman of the Board and member of the 
Compensation Committee, Audit Committee and Governance and Nominating Committee during fiscal 2012 and fiscal 2013.  

40 

   
   
   
   
   
   
   
   
   
   
   
   
  
On May 3, 2012, Ms. Muller was granted options to purchase a total of 166,438 shares of the Company’s common stock with an 
exercise price of $0.44 per share of which 116,438 shares immediately vested and the remaining 50,000 shares vested on September 22, 2012 
for her service as a director, Chairman of the Compensation Committee and Nomination and Governance Committee, and a member of the 
Audit Committee during fiscal 2012 and fiscal 2013. The options to purchase a total of 127,771 shares were issued in connection with the 
services she provided during fiscal 2012.  

On July 12, 2012, Mr. Michelin, Mr. Wasserman, and Ms. Muller were each granted an option to purchase 100,000 shares of the 
Company’s common stock with an exercise price of $0.36 per share which were fully vested upon issuance for their service as the Office of 
the Chief Executive for the months of April, May, and June 2012.  

Annual awards were granted at the shareholders meeting on September 13, 2012. Mr. Michelin, Ms. Muller and Mr. Wasserman were 

each granted an option to purchase 50,000, 50,000 and 80,000 shares, respectively, of the Company’s common stock with an exercise price of 
$0.30 per share  

On October 9, 2012, Mr. Michelin, Mr. Wasserman, and Ms. Muller were each granted an option to purchase 125,000 shares of the 

Company’s common stock with an exercise price of $0.17 per share which were fully vested upon issuance for their service as the Office of 
the Chief Executive for the months of July, August and September 2012.  

On December 12, 2012, Mr. Michelin, Mr. Wasserman, and Ms. Muller were each granted an option to purchase 50,000, 100,000 and 

100,000 shares, respectively, of the Company’s common stock with an exercise price of $0.18 per share which were fully vested upon 
issuance for their service as the Office of the Chief Executive for the month of October and part of November 2012.  

Annual awards were granted at the shareholders meeting on September 6, 2013. Mr. Rathmann and Mr. Wasserman were each granted 

an option to purchase 80,000 and 50,000 shares, respectively, of the Company’s common stock with an exercise price of $0.38 per share.  

On September 13, 2013, Mr. Zecchini was granted an option to purchase 100,000 shares of the Company’s common stock with an 

exercise price of $0.40 per share when he joined the board.  

The following table sets forth the director compensation of the non-employee directors of the Company during fiscal 2014.  

Name 
Adam M. Michelin 
Karen Muller 
Richard Rathmann 
Stephen Wasserman 
Edward Zecchini 

Fees Earned  
Or Paid in  
Cash  
($)(1)  

   $ 

24,000      $ 
24,000     
56,445     
52,108     
26,400     

Stock  
Awards  
($) 

Option  
Awards  
($)(2) 

All Other  
Compensation 

($) 

—     $ 
—    
—    
—    
—    

—    
—    
26,300     
16,438     
34,632     

—     $ 
—    
—    
—    
—    

Total  
($) 

24,000   
24,000   
82,745   
68,546   
61,032   

(1) Fees earned or paid in cash as shown in this schedule represent payments and accruals for directors’ services earned during fiscal 2014.  

(2) This column represents the total grant date fair value of all stock options granted in fiscal 2014. Pursuant to SEC rules, the amounts shown 
exclude the impact of estimated forfeitures related to service-based vesting conditions. For information on the valuation assumptions with 
respect to the grants made in fiscal 2014, refer to Note 2 “ Summary of Significant Accounting Policies” in the accompanying consolidated 
financial statements.  

AUDIT COMMITTEE REPORT  

The  Audit  Committee  of  the  Board  has  furnished  the  following  report  on  the  Company’s  audit  procedures  and  its  relationship  with  its 

independent registered public accounting firm for fiscal 2014.  

The Audit Committee has reviewed and discussed with the Company’s management the audited consolidated financial statements. The Audit 
Committee  has  also  discussed  with  KMJ  Corbin  &  Company  LLP  the  matters  required  to  be  discussed  by  Auditing  Standards  No.  61,  as 
amended (AICPA Professional  Standards, Vol.  1, AU Section 380), as adopted by the Public Company  Accounting Oversight Board  in Rule 
3200T which includes, among other items, matters related to the conduct of the audit of the Company’s consolidated financial statements.  

41 

   
    
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
    
    
    
 
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
The Company’s independent registered public accounting firm, KMJ Corbin & Company LLP, also  provided to the Audit Committee the 
written disclosures and the letter required by the Public Company Accounting Oversight Board (PCAOB) Ethics and Independence Rules and 
Standards  as  adopted  by  the  PCAOB,  and  the  Audit  Committee  discussed  with  the  independent  registered  public  accounting  firm  that  firm’s 
independence.  

Based  on  the  review  and  discussions  referred  to  above,  the  Audit  Committee  recommended  to  the  Board  that  the  audited  consolidated 

financial statements be included in the Company’s Annual Report Form 10-K for fiscal 2014 filed with the SEC.  

Audit Committee 
Stephen E. Wasserman (Chairman) 
Richard Rathmann  
Edward Zecchini  

Pursuant to Instruction 1 to Item 407(d) of Regulation S-K, the information set forth under “Audit Committee Report” shall not be deemed to 
be “soliciting material” or to be “filed” with the SEC or subject to Regulation 14A or 14C, other than as provided in Item 407 of Regulation S-K, 
or  to  the  liabilities  of  Section  18  of  the  Exchange  Act,  except  to  the  extent  that  we  specifically  request  that  the  information  be  treated  as 
soliciting  material  or  specifically  incorporate  it  by  reference  into  a  document  filed  under  the  Securities  Act  or  the  Exchange  Act.  Such 
information will not be deemed incorporated by reference into any filing under the Securities Act or the Exchange Act, except to the extent we 
specifically incorporate it by reference.  

Item 12. 

Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters. 

The following table sets forth information with respect to the beneficial ownership of the Company’s common stock as of June 13, 2014, by 
each  person  or  group  of  affiliated  persons  known  to  the  Company  to  beneficially  own  5%  or  more  of  its  common  stock,  each  director,  each 
named executive officer, and all of its directors and named executive officers as a group. As of June 13, 2014, there were 59,987,846 shares of 
common stock outstanding. Unless otherwise indicated, the address of each beneficial owner listed below is c/o Cryoport, Inc., 20382 Barents 
Sea Circle, Lake Forest, CA 92630.  

The following table gives effect to the shares of common stock issuable within 60 days of June 13, 2014, upon the exercise of all options and 
other rights beneficially owned by the indicated stockholders on that date. Unless otherwise indicated, the persons named in the table have sole 
voting and sole investment control with respect to all shares beneficially owned.  

Beneficial Owner 
Executive Officers and Directors: 
Jerrell W. Shelton 
Robert S. Stefanovich 
Adam M. Michelin 
Karen M. Muller 
Richard Rathmann 
Stephen E. Wasserman 
Edward Zecchini 
Ramkumar Mandalam Ph.D. 

All directors and named executive officers as a group (8 persons) 

Other Stockholders: 
Cranshire Capital Master Fund(3) 

Total for all Directors, Executive Officers and Other Stockholders 

42 

Number of Shares  
of Preferred Stock 
Beneficially Owned   

Number of Shares  
of Common Stock  
Beneficially Owned (2)   

Percentage of Shares 

of Common Stock  
Beneficially Owned   

11,314   

9,376 (4)     

3,130,045 (1)     
350,984 (1)     
536,891 (1)     
541,438 (1)     
4,090,018 (1)     
589,189 (1)     
83,333 (1)     
8,333 (1)     

9,330,231 (1)     

3,449,625 (1)     

12,779,856   

5.0 % 
 *   
 *   
 *   
6.6 % 
1.0 % 
*   
 *   

14.0 % 

5.4 % 

18.2 % 

   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
 
    
  
    
  
    
  
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
  
    
    
    
    
    
    
    
    
    
  
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
  
    
    
    
    
    
    
    
    
    
    
*  Represents less than 1% 

(1)  Includes  shares  which  individuals  shown  above  have  the  right  to  acquire  as  of  June  13,  2014,  or  within  60 days  thereafter,  pursuant  to 
outstanding  stock options and/or  warrants  as  follows:  Mr.  Shelton—2,470,045  shares; Mr. Stefanovich—350,984  shares;  Mr.  Michelin—
532,755 shares; Ms. Muller—541,438 shares; Mr. Rathmann—2,166,593 of which 683,059 are individually owned by Mr. Rathmann and 
1,483,534 are owned by GBR Investments,LLC of which Mr. Rathmann is the manager; Mr. Wasserman—589,189; Mr. Zecchini—83,333; 
Dr. Mandalam—8,333 shares; Cranshire Capital—3,449,625 shares. 

(2)  The number and percentage of shares beneficially owned is determined in accordance with Rule 13d-3 of the Securities Exchange Act of 
1934, and the information is not necessarily indicative of beneficial ownership for any other purpose. Under such rule, beneficial ownership 
includes any shares as to which the selling security holder has sole or shared voting power or investment power and also any shares which 
the selling security holder has the right to acquire within 60 days. 

(3)  Cranshire Capital Master Fund, Ltd. address is 3100 Dundee Road, Suite 703, Northbrook, IL 60062. 

(4)  GBR Investments, LLC of which Mr. Rathmann is the manager. 

Equity Compensation Plan Information  

We currently maintain three equity compensation plans, referred to as the 2002 Stock Incentive Plan (the “2002 Plan”), the 2009 Stock 
Incentive Plan (the “2009 Plan”) and the 2011 Stock Incentive Plan (the “2011 Plan”). Our Compensation Committee is responsible for making, 
reviewing and recommending grants of options and other awards under these plans which are approved by the Board.  

The 2002 Plan, which was approved by our stockholders in October 2002, allows for the grant of options to purchase up to 500,000 shares 
of the Company’s common stock. The 2002 Plan provides for the granting of options to purchase shares of our common stock at prices not less 
than the fair market value of the stock at the date of grant and generally expire 10 years after the date of grant. The stock options are subject to 
vesting requirements, generally three or four years. The 2002 Plan also provides for the granting of restricted shares of common stock subject to 
vesting requirements. As of June 30, 2013, no shares are available for future issuances as the 2002 Plan has expired.  

The 2009 Plan, which was approved by our stockholders at our 2009 Annual Meeting of Stockholders held on October 9, 2009, provides 
for the grant of stock-based incentives. The 2009 Plan allows for the grant of up to 1,200,000 shares of our common stock for awards to our 
officers,  directors,  employees  and  consultants.  The  2009  Plan  provides  for  the  grant  of  incentive  stock  options,  nonqualified  stock  options, 
restricted stock  rights,  restricted stock, performance  share units, performance  shares, performance  cash awards, stock  appreciation rights, and 
stock  grant  awards.  The  2009  Plan  also  permits  the  grant  of  awards  that  qualify  for  the  “performance-based  compensation”  exception  to  the 
$1,000,000 limitation on the deduction of compensation imposed by Section 162(m) of the Code. As of June 13, 2014, a total of 303,768 shares 
of our common stock remained available for future grants under the 2009 Plan.  

The 2011 Plan, as amended, which was approved by our stockholders at our 2011 Annual Meeting of Stockholders held on September 22, 
2011 and, with respect to the amendments, at our 2012 and 2013 Annual Meeting of Stockholders held on September 13, 2012 and September 6, 
2013,  respectively,  provides  for  the  grant  of  stock-based  incentives.  The  2011  Plan  allows  for  the  grant  of  up  to  12,400,000  shares  of  our 
common stock for awards to our officers, directors, employees and consultants. The 2011 Plan provides for the grant of incentive stock options, 
nonqualified stock options, restricted stock rights, restricted stock, performance share units, performance shares, performance cash awards, stock 
appreciation  rights,  and  stock  grant  awards.  The  2011  Plan  also  permits  the  grant  of  awards  that  qualify  for  the  “performance-based 
compensation” exception to the $1,000,000 limitation on the deduction of compensation imposed by Section 162(m) of the Code. Awards may 
be granted under the 2011 Plan until September 21, 2021 or until all shares available for Awards under the 2011 Plan have been purchased or 
acquired unless the stockholders of the Company vote to approve an extension of the 2011 Plan prior to such expiration date. As of June 13, 
2014, a total of 7,248,069 shares remained available for future grants under the 2011 Plan.  

In  addition  to  the  stock  options  issued  pursuant  to  the  Company’s  three  stock  incentive  plans,  the  Company  has  granted  warrants  to 
employees, officers, non-employee directors and consultants. The warrants are generally not subject to vesting requirements and have ten-year 
terms.  

43 

   
   
   
   
   
   
   
   
   
   
   
   
  
The following table sets forth certain information as of June 13, 2014 concerning the Company’s common stock that may be issued upon 
the exercise of options or warrants or pursuant to purchases of stock under the 2002 Plan, the 2009 Plan, the 2011 Plan and other stock based 
compensation:  

Plan Category 
Equity compensation plans approved by stockholders 
Equity compensation plans not approved by stockholders(1) 

  (a)  
 Number of Securities 

 to be Issued Upon 
the  
 Exercise of  
 Outstanding Options 

 and Warrants 

  (b)  
 Weighted-
Average  
 Exercise Price 
of  
 Outstanding  
 Options and  
 Warrants 

68,540,648      $ 
6,548,577      $ 

75,089,225        

  (c)  
Available for Future  
Issuance Under Equity  
Compensation Plans  
(Excluding Securities  
Reflected in Column (a))   
7,551,837   
N/A   

0.79        
0.26        

7,551,837   

(1)  During November 5, 2012 through June 13, 2014, a total of 6,548,577 options were granted to employees outside of an option plan. In the 
past the Company has issued warrants to purchase 327,415 shares of common stock in exchange for services provided to the Company, of 
which warrants to purchase 262,855 shares of common stock are outstanding. The exercise prices ranged from $2.80 to $10.80 and 
generally vested upon issuance. 15 consultants and former officers and directors received warrants to purchase 327,415 shares of common 
stock in this manner. 

Item 13. Certain Relationships and Related Transactions, and Director Independence.  

The Company has established policies and other procedures regarding approval of transactions between the Company and any employee, 
officer,  director,  and  certain  of  their  family  members  and  other  related  persons,  including  those  required  to  be  reported  under  Item 404  of 
Regulation S-K. These policies and procedures are generally not in writing, but are evidenced by long standing principles set forth in our Code 
of Conduct or adhered to by our Board. As set forth in the Audit Committee Charter, the Audit Committee reviews and approves all related-party 
transactions after reviewing such transaction for potential conflicts of interests and improprieties. Accordingly, all such related-party transactions 
are submitted to the Audit Committee for ongoing review and oversight. Generally speaking, we enter into related-party transactions only on 
terms that we believe are at least as favorable to our company as those that we could obtain from an unrelated third party.  

The  following  related-party  transaction  were  approved  or  ratified  by  at  least  two  independent  directors  and  future  material  affiliated 
transactions will be approved by a majority of the independent directors who do not have an interest in the transaction and who had access, at the 
issuer’s expense, to issuer’s or independent legal counsel.  

On  May  9,  2013,  Richard  Rathmann,  Director,  invested  $100,000  in  the  Bridge  Notes  offered  by  the  Company  to  certain  accredited 
investors.  For information on terms related to the Bridge Notes, refer to Note 8 “Convertible Debentures Payable” in the Company’s Form 10-K 
for  the  period  ended March  31,  2013 filed  with  the  SEC on  June  25,  2013.   In  addition,  on  July  12,  2013,  GBR  Investments,  LLC,  invested 
$100,000 in the Bridge Notes offered by the Company to certain accredited investors and also received a warrant to purchase 400,000 shares of 
common  stock  at  an  exercise  price  of  $0.25  per  share,  pursuant  to  the  terms  of  such  offering.   Richard  Rathmann  is  the  Manager  of  GBR 
investments, LLC and is considered an indirect beneficial owner of these securities.  

During the year ended March 31, 2014, the Company issued to certain accredited investors various unsecured promissory notes with the 
terms as described under Note 7 in the accompanying consolidated financial statements. These unsecured promissory notes included $120,000 of 
the  5%  Bridge  Notes  issued  to  Jerrell  Shelton,  the  Company’s  Chief  Executive  Officer,  $100,000  of  the  Bridge  Notes  issued  to  Richard 
Rathmann, a member of the Board of Directors of the Company, $200,000 of the Bridge Notes and $100,000 of the 5% Bridge Notes issued to 
GBR Investments, LLC, of which Richard Rathmann, is the manager. Subsequent to year end, in May 2014, both note holders elected to convert 
all principal and interest into a newly established Class A Convertible Preferred Stock and warrants to purchase common stock of Cryoport as 
further described in Note 15 in the accompanying consolidated financial statements.  

SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE  

Section  16(a)  of the Exchange Act  requires the Company’s directors and executive officers, and persons who own  more than 10% of a 
registered class  of  the  Company’s  equity  securities,  to  file  with the  SEC  reports  of  beneficial  ownership  and  reports  of  changes in  beneficial 
ownership in the Company’s securities. Such directors, executive officers and 10% stockholders are also required to furnish the Company with 
copies of all Section 16(a) forms they file.  

44 

   
   
   
   
   
   
   
   
   
   
   
  
  
 
 
    
    
     
     
  
     
         
         
    
  
     
         
Based solely on a review of the copies of such forms received by it, the Company believes that during fiscal 2014, all Section 16(a) filings 

applicable to its directors, officers, and 10% stockholders were filed on a timely basis.  

Item 14.   Principal Accountant Fees and Services  

Independent Registered Public Accounting Firms Fees  

The  following  table  shows  the  fees  that  were  billed  to  us  for  the  audit  and  other  services  provided  by  KMJ  Corbin  &  Company  LLP 

(“KMJ”) for the Company’s fiscal 2014 and fiscal 2013.  

Audit Fees 
Audit-Related Fees 
Tax Fees 

2014  

2013  

   $ 

   $ 

69,325      $ 
—    
7,100     
76,425      $ 

66,050   
11,960   
6,275   
84,285   

The fees billed to us by KMJ during or related to the fiscal years ended March 31, 2014 and 2013 consist of audit fees, audit-related fees 

and tax fees, as follows:  

Audit Fees . Represents the aggregate fees billed to us for professional services rendered for the audit of our annual consolidated financial 

statements and for the reviews of our consolidated financial statements included in our Form 10-Q filings for each fiscal quarter.  

Audit-Related Fees. Represents the aggregate fees billed to us for assurance and related services that are reasonably related to the 
performance of the audit and review of our consolidated financial statements that are not already reported in Audit Fees. These services include 
accounting consultations and attestation services that are not required by statute such as S-1 and S-8 filings.  

Tax Fees. Represents the aggregate fees billed to us for professional services rendered for tax returns, compliance and tax advice.  

All Other Fees. We did not incur any other fees to KMJ during the fiscal years ended March 31, 2014 and 2013.  

Policy on Audit Committee Pre-Approval of Fees  

The Audit Committee must pre-approve all services to be performed for us by our independent auditors. Pre-approval is granted usually 
at  regularly  scheduled  meetings  of  the  Audit  Committee.  If  unanticipated  items  arise  between  regularly  scheduled  meetings  of  the  Audit 
Committee, the  Audit  Committee has  delegated authority to the  chairman of  the  Audit  Committee to pre-approve services, in which case  the 
chairman  communicates  such  pre-approval  to  the  full  Audit  Committee  at  its  next  meeting.  The  Audit  Committee  also  may  approve  the 
additional unanticipated services by either convening a special meeting or acting by unanimous written consent. During the fiscal years ended 
March 31, 2014 and 2013, all services billed by KMJ were pre-approved by the Audit Committee in accordance with this policy.  

Item 15.   Exhibits and Financial Statement Schedules  

(a)(1) Consolidated Financial Statements:  

PART IV  

Report of Independent Registered Public Accounting Firm  
Consolidated Balance Sheets as of March 31, 2014 and 2013  
Consolidated Statements of Operations for the years ended March 31, 2014 and 2013  
Consolidated Statements of Stockholders’ (Deficit) Equity for the years ended March 31, 2014 and 2013  
Consolidated Statements of Cash Flows for the years ended March 31, 2014 and 2013  
Notes to Consolidated Financial Statements  

Page  
F-2 
F-3 
F-4 
F-5 
F-6 
F-7 

(a)(2)  Financial  Statement  Schedules:  All  financial  statement  schedules  are  omitted  because  they  are  not  applicable  or  the  required 

information is included in the Consolidated Financial Statements or notes thereto.  

(a)(3) Exhibits.  

45 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
    
  
  
  
  
  
  
  
  
  
Exhibit 
No.  

Exhibits  

Description  

3.1 

3.2 

3.3 

  Amended and Restated Articles of Incorporation of the Company, as amended.  Incorporated by reference to Exhibit 3.1 to the 
Company’s Quarterly Report on Form 10-Q for the Quarter Ended September 30, 2012. 

  Amended and Restated Bylaws of the Company.  Incorporated by reference to Exhibit 3.2 of the Company’s Current Report on Form 8-
K dated October 23, 2012. 

  Cryoport Systems, Inc. 2002 Stock Incentive Plan adopted by the Board of Directors on October 1, 2002.  Incorporated by reference to 
Exhibit 3.13 to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

3.4 

  Certificate of Designation.  Incorporated by reference to Exhibit 3.1 of the Company’s Current Report on Form 8-K dated May 2, 2014. 

4.1.1 

  Form of Debenture—Original Issue Discount 8% Secured Convertible Debenture dated September 28, 2007. Incorporated by reference 
to Cryoport’s Registration Statement on Form SB-2 dated November 9, 2007. 

4.1.2 

  Amendment to Convertible Debenture dated February 19, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K 
dated March 7, 2008 and referred to as Exhibit 10.1.10. 

4.1.3 

  Amendment to Convertible Debenture dated April 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 
April 30, 2008 and referred to as Exhibit 10.1.11. 

4.1.4 

  Annex to Amendment to Convertible Debenture dated April 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 
8-K dated April 30, 2008 and referred to as Exhibit 10.1.11.1. 

4.1.5 

  Amendment to Convertible Debenture dated August 29, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K 
dated August 29, 2008. 

4.1.6 

  Amendment to Convertible Debenture effective January 27, 2009 and dated February 20, 2009. Incorporated by reference to Cryoport’s 
Current Report on Form 8-K dated February 19, 2009. 

4.1.7 

4.1.8 

4.1.9 

  Amendment to Debentures and Warrants with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified Strategy 
Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated September 1, 2009. Incorporated by reference to 
Cryoport’s Current Report on Form 8-K dated September 17, 2009. 

  Amendment to Debentures and Warrants, Agreement and Waiver with Enable Growth Partners LP, Enable Opportunity Partners LP, 
Pierce Diversified Strategy Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated January 12, 2010. 
Incorporated by reference to Cryoport’s Current Report on Form 8-K dated January 15, 2010. 

  Amendment Agreement with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified Strategy Master Fund 
LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated February 1, 2010. Incorporated by reference to Cryoport’s Current 
Report on Form 8-K dated February 3, 2010. 

4.1.10    Amended and Restated Amendment Agreements with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified 

Strategy Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated  
February 19, 2010. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated February 26, 2010. 

4.1.11    First Amendment to Amended and Restated Amendment Agreements with Enable Growth Partners LP, Enable Opportunity Partners 
LP, Pierce Diversified Strategy Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated February 23, 2010. 
Incorporated by reference to Cryoport’s Current Report on Form 8-K dated February 26, 2010.  

4.2 

4.3 

  Form of Common Stock Purchase Warrant dated September 28, 2007. Incorporated by reference to Cryoport’s Registration Statement 
on Form SB-2 dated November 9, 2007. 

  Original Issue Discount 8% Secured Convertible Debenture dated May 30, 2008. Incorporated by reference to Cryoport’s Current 
Report on Form 8-K dated June 9, 2008. 

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Exhibit 
No.  

Description  

4.4 

4.5 

4.6 

4.7 

4.8 

4.9 

4.10 

4.11 

4.12 

4.13 

4.14 

4.15 

4.16 

4.17 

  Common Stock Purchase Warrant dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 
June 9, 2008. 

  Common Stock Purchase Warrant dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 
June 9, 2008 . 

  Form of Warrant and Warrant Certificate in connection with the February 25, 2010 public offering. Incorporated by reference to 
Cryoport’s Amendment No. 5 to Form S-1/A Registration Statement dated February 9, 2010. 

  Form of Securities Purchase Agreement in connection with the August to October 2010 private placement. Incorporated by reference to 
Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Form of First Amendment to Security Purchase Agreement in connection with the August to October 2010 private placement. 
Incorporated by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Form of Securities Purchase Agreement (Continuation of the Placement) in connection with the August to October 2010 private 
placement. Incorporated by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Registration Rights Agreement in connection with the August to October 2010 private placement. Incorporated by reference to 
Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Form of Joinder to Registration Rights Agreement in connection with the August to October 2010 private placement. Incorporated by 
reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Form of Securities Purchase Agreement in connection with the February 2011 private placement. Incorporated by reference to 
Cryoport’s Registration Statement on Form S-1 dated April 1, 2011. 

  Form of Registration Rights Agreement in connection with the February 2011 private placement. Incorporated by reference to 
Cryoport’s Registration Statement on Form S-1 dated April 1, 2011. 

  Form of Warrant in connection with the August to October 2010 private placement. Incorporated by reference to Cryoport’s 
Registration Statement on Form S-1/A dated April 22, 2011. 

  Form of Warrant in connection with the February 2011 private placement. Incorporated by reference to Cryoport’s Registration 
Statement on Form S-1/A dated April 22, 2011. 

  Form of Securities Purchase Agreement. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC on 
February 24, 2012. 

  Form of Registration Rights Agreement. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC on 
February 24, 2012. 

4.18 

  Form of Warrant. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC on February 24, 2012. 

4.19 

  Warrant issued to Rodman & Renshaw, LLC in connection with the February 25, 2010 public offering. Incorporated by reference to 
CryoPort’s Registration Statement on Form S-1 dated October 19, 2010. 

4.20 

4.21 

Form of Warrant issued with Convertible Promissory Notes.  Incorporated by reference to Exhibit 4.20 of Cryoport’s Quarterly Report 
on Form 10-Q for the Quarter Ended September 30, 2013. 

Form of Warrant issued upon Conversion of Convertible Promissory Notes.  Incorporated by reference to Exhibit 4.21 of Cryoport’s 
Quarterly Report on Form 10-Q for the Quarter Ended September 30, 2013. 

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Exhibit 
No.  

4.22 

4.23 

Description  

Form of Warrant Issued to Placement Agents.  Incorporated by reference to Exhibit 4.22 of Cryoport’s Quarterly Report on Form 10-Q 
for the Quarter Ended September 30, 2013. 

Form of Warrant issued with Convertible Promissory Notes (5% Bridge Notes).  Incorporated by reference to Exhibit 4.23 of 
Cryoport’s Quarterly Report on Form 10-Q for the Quarter Ended December 31, 2013. 

4.24+ 

  Form of Warrant issued in connection with the May 2014 private placement. 

10.1.1    Commercial Promissory Note between Cryoport, Inc. and D. Petreccia executed on August 26, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.2    Commercial Promissory Note between Cryoport, Inc. and J. Dell executed on September 1, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.3    Commercial Promissory Note between Cryoport, Inc. and P. Mullens executed on September 2, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.4    

Commercial Promissory Note between Cryoport, Inc. and R. Takahashi executed on August 25, 2005. Incorporated by reference to 
Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.5.2    

Second Amendment To Lease: Renewal dated August 24, 2009, between CryoPort, Inc. and Viking Inventors-Barents Sea LLC. 
Incorporated by reference to Cryoport’s Amendment No. 1 to Form S-1/A Registration Statement dated January 12, 2010. 

10.5.3    

Third Amendment to Lease: Renewal dated June 8, 2010 between Viking Investors Barents Sea, LLC. Incorporated by reference to 
Exhibit 10.5.3 to Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2013. 

10.6 

10.7 

10.9 

Securities Purchase Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form SB-
2 dated November 9, 2007 and referred to as Exhibit 10.6. 

  Registration Rights Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form SB-
2 dated November 9, 2007 and referred to as Exhibit 10.7. 

  Security Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form SB-2 dated 
November 9, 2007 and referred to as Exhibit 10.8. 

10.10 

  Securities Purchase Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 
2008 and referred to as Exhibit 10.10. 

10.11 

  Registration Rights Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 
2008 and referred to as Exhibit 10.11. 

10.12 

  Waiver dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 2008 and referred to as 
Exhibit 10.12. 

10.13 

  Security Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 2008 and 
referred to as Exhibit 10.13. 

10.14 

  Consent, Waiver and Agreement with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified Strategy Master 
Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. and its subsidiary dated July 30, 2009. Incorporated by reference to 
Cryoport’s Current Report on Form 8-K dated July 29, 2009 and referred to as Exhibit 10.15. 

10.15.1   Master Consulting and Engineering Services Agreement dated October 9, 2007 with KLATU Networks, LLC and CryoPort, Inc. 

Incorporated by reference to Cryoport, Inc.’s Registration Statement on Form S-8 dated March 25, 2009 and referred to as Exhibit 10.2. 

48 

   
   
  
  
  
    
  
  
    
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
Exhibit 
No.  

Description  

10.15.2   First Amendment to Master Consulting and Engineering Services Agreement dated as of April 23, 2009, between CryoPort, Inc. and 

KLATU Networks, LLC. Incorporated by reference to Cryoport’s Registration Statement on Form S-1/A dated December 17, 2010 and 
referred to as Exhibit 10.32. 

10.15.3   Second Amendment to Master Consulting and Engineering Services Agreement dated as of November 1, 2010, between CryoPort, Inc. 
and KLATU Networks, LLC. Incorporated by reference to Cryoport’s Registration Statement on Form S-1/A dated December 17, 2010 
and referred to as Exhibit 10.33. 

10.16 

  Stock Option Agreement ISO under the 2002 Stock Incentive Plan of Cryoport Systems, Inc. Incorporated by reference to Exhibit 3.14 
to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

10.17 

  Stock Option Agreement NSO under the 2002 Stock Incentive Plan of Cryoport Systems, Inc. Incorporated by reference to Exhibit 3.15 
to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

10.18 

  2009 Stock Incentive Plan of the Company.  Incorporated by reference to Exhibit 10.21 of the Company’s Current Report on Form 8-K 
dated October 15, 2009 and referred to as Exhibit 10.21. 

10.19 

  Form Incentive Stock Option Award Agreement under the 2009 Stock Incentive Plan of the Company. Incorporated by reference to 
Exhibit 10.22 of the Company’s Current Report on Form 8-K dated October 9, 2009. 

10.20 

  Form of Non-Qualified Stock Option Award Agreement under the 2009 Stock Incentive Plan of the Company. Incorporated by 
reference to Exhibit 10.25 of the Company’s Registration Statement on Form S-8 dated April 27, 2010. 

10.21 

  2011 Stock Incentive Plan (as amended and restated).  Incorporated by reference to Exhibit B of the Company’s Definitive Proxy 
Statement on Schedule 14A filed with the SEC on July 30, 2012. 

10.22 

  Form of Stock Option Award Agreement. Incorporated by reference to Exhibit 10.37 to Cryoport’s Current Report on Form 8-K filed 
with the SEC on September 27, 2011. 

10.23 

  Form of Non-Qualified Stock Option Award Agreement. Incorporated by reference to Exhibit 10.38 to Cryoport’s Current Report on 
Form 8-K filed with the SEC on September 27, 2011. 

10.24 

  Form of Convertible Promissory Note. Incorporated by reference to Exhibit 10.24 to Cryoport’s Annual Report on Form 10-K filed 
with the SEC on June 25, 2013. 

10.25 

  Form of Amendment to Convertible Promissory Note. Incorporated by reference to Exhibit 10.25 to Cryoport’s Annual Report on Form 
10-K filed with the SEC on June 25, 2013. 

10.26 

  Form of Convertible Promissory Note. Incorporated by reference to Exhibit 10.26 to Cryoport’s Annual Report on Form 10-K filed 
with the SEC on June 25, 2013. 

10.27*    Employment Agreement between the Company and Jerrell Shelton.  Incorporated by reference to the Company’s Current Report on 

Form 8-K filed on November 6, 2012 and referred to as Exhibit 10.45. 

10.28 

  Stock Option Agreement dated November 5, 2012 between the Company and Jerrell Shelton. Incorporated by reference to Exhibit 
10.28 to Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2013. 

10.29#    Master Agreement between the Company and Federal Express Corporation dated January 1, 2013.  Incorporated by reference to the 

Company’s Current Report on Form 8-K filed on January 8, 2013 and referred to as Exhibit 10.1. 

10.30*    Employment Agreement dated June 28, 2013 with Jerrell Shelton.  Incorporated by reference to Exhibit 10.30 to Cryoport’s Current 

Report on Form 8-K filed with the SEC on July 3, 2013. 

10.31 

  Form of Convertible Promissory Notes issued with Warrants.  Incorporated by reference to Exhibit 10.31 to Cryoport’s Quarterly 
Report on Form 10-Q for the Quarter Ended September 30, 2013. 

49 

   
   
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
Exhibit  
No.  

10.32 

10.33 

Description  

  Form of Letter of Tender and Exchange.  Incorporated by reference to Exhibit 10.32 to Cryoport’s Quarterly Report on Form 10-Q 
for the Quarter Ended September 30, 2013. 

  Form of Convertible Promissory Note (5% Bridge Note) issued with Warrants.  Incorporated by reference to Exhibit 10.33 to 
Cryoport’s Quarterly Report on Form 10-Q for the Quarter Ended December 31, 2013. 

10.34+ 

  Form of Subscription Agreement in connection with the May 2014 private placement. 

10.35+ 

  Form of Election to Convert in connection with the May 2014 private placement. 

21+ 

  Subsidiaries of Registrant. 

23.1+ 

  Consent of Independent Registered Public Accounting Firm—KMJ Corbin & Company LLP. 

31.1+ 

  Certification of Principal Executive Officer, pursuant to Rule 13a-14(a)/15d-14(a) of the Securities Exchange Act of 1934 . 

31.2+ 

  Certification of Principal Financial Officer, pursuant to Rule 13a-14(a)/15d-14(a) of the Securities Exchange Act of 1934 . 

32.1+ 

32.2+ 

  Certification of Principal Executive Officer, pursuant to Rule 13a-14(b)/15d-14(b) of the Securities Exchange Act of 1934 and 
18 U.S.C. Section 1350. 

  Certification of Principal Financial Officer, pursuant to Rule 13a-14(b)/15d-14(b) of the Securities Exchange Act of 1934 and 
18 U.S.C. Section 1350. 

101.INS†    XBRL Instance Document. 

101.SCH†   XBRL Taxonomy Extension Schema Document. 

101.CAL†   XBRL Taxonomy Extension Calculation Linkbase Document. 

101.DEF†   XBRL Taxonomy Extension Definition Linkbase Document. 

101.LAB†   XBRL Taxonomy Extension Label Linkbase Document. 

101.PRE†   XBRL Taxonomy Extension Presentation Linkbase Document. 

* 
# 

+ 
† 

Indicates a management contract or compensatory plan or arrangement. 
Confidential portions omitted and filed separately with the U.S. Securities and Exchange Commission pursuant to Rule 24b-2 promulgated 
under the Securities Exchange Act of 1934, as amended. 
Filed herewith. 
XBRL (Extensible Business Reporting Language) information is furnished and not filed or a part of a registration statement or prospectus 
for purposes of sections 11 or 12 of the Securities Act of 1933, as amended, is deemed not filed for purposes of section 18 of the Securities 
Exchange Act of 1934, as amended, and otherwise is not subject to liability under these sections or otherwise incorporated by reference. 

50 

   
   
   
   
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this Annual 

Report on Form 10-K to be signed on its behalf by the undersigned, thereunto duly authorized.  

SIGNATURES  

Cryoport, Inc.  

By:  /s/ JERRELL W. SHELTON  

Jerrell W. Shelton  

   Chief Executive Officer and Director 

Date: June 25, 2014  

Pursuant to  the requirements  of  the Securities  Exchange  Act  of  1934,  this  Annual  Report on Form 10-K  has been signed below  by  the 

following persons on behalf of the Registrant and in the capacities and on the dates indicated:  

Signature  

/s/ JERRELL W. SHELTON  

Jerrell W. Shelton  

/s/ ROBERT S. STEFANOVICH  

Robert S. Stefanovich  

/s/ RICHARD G. RATHMANN  

Richard G. Rathmann  

/s/ STEPHEN E. WASSERMAN  

Stephen W. Wasserman  

/s/ EDWARD ZECCHINI  

Edward Zecchini  

/s/ RAMKUMAR MANDALAM, PH.D.  

Ramkumar Mandalam Ph.D.  

Title  

Chief Executive Officer and Director  
(Principal Executive Officer)  

Chief Financial Officer  
(Principal Financial and Accounting Officer)  

Director 

Director 

Director 

Director 

51 

Date  

June 25, 2014 

June 25, 2014 

June 25, 2014 

June 25, 2014 

June 25, 2014 

June 25, 2014 

   
   
   
   
    
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
Cryoport, Inc. and Subsidiary  
Consolidated Financial Statements  
As of March 31, 2014 and 2013  
For Each of the Two Years Ended March 31, 2014  

52 

   
   
  
Cryoport, Inc. and Subsidiary  
Consolidated Financial Statements  
INDEX TO FINANCIAL STATEMENTS  

Report of Independent Registered Public Accounting Firm  

Consolidated Balance Sheets as of March 31, 2014 and 2013  
Consolidated Statements of Operations for the years ended March 31, 2014 and 2013  
Consolidated Statements of Stockholders’ (Deficit) Equity for the years ended March 31, 2014 and 2013  
Consolidated Statements of Cash Flows for the years ended March 31, 2014 and 2013  

Notes to Consolidated Financial Statements  

Page 
F-2 
F-3 
F-4 
F-5 
F-6 
F-7 

F- 1 

   
   
   
  
  
The Board of Directors and  
Stockholders of Cryoport, Inc.  

Report of Independent Registered Public Accounting Firm  

We have audited the accompanying consolidated balance sheets of CryoPort, Inc. (the “Company”) as of March 31, 2014 and 2013, and the 
related consolidated statements of operations, stockholders’ (deficit) equity and cash flows for each of the years in the two-year period ended 
March 31, 2014. These consolidated financial statements are the responsibility of the Company’s management. Our responsibility is to express 
an opinion on these consolidated financial statements based on our audits.  

We  conducted  our  audits  in  accordance  with  the  standards  of  the  Public  Company  Accounting  Oversight  Board  (United  States).  Those 
standards require that we plan and perform the audits to obtain reasonable assurance about whether the consolidated financial statements are free 
of  material  misstatement.  An  audit  includes  examining,  on  a  test  basis,  evidence  supporting  the  amounts  and  disclosures  in  the  consolidated 
financial  statements.  The  Company  is  not  required  to  have,  nor  were  we  engaged  to  perform,  an  audit  of  its  internal  control  over  financial 
reporting.  Our  audits  included  consideration  of  internal  control  over  financial  reporting  as  a  basis  for  designing  audit  procedures  that  are 
appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the Company’s internal control over 
financial reporting. Accordingly, we express no such opinion.  An audit also includes assessing the accounting principles used and significant 
estimates  made  by  management,  as  well  as  evaluating  the  overall  consolidated  financial  statement  presentation.  We  believe  that  our  audits 
provide a reasonable basis for our opinion.  

In  our  opinion,  the  consolidated  financial  statements  referred  to  above  present  fairly,  in  all  material  respects,  the  consolidated  financial 
position of CryoPort, Inc. at March 31, 2014 and 2013, and the results of its operations and its cash flows for each of the years in the two-year 
period ended March 31, 2014 in conformity with accounting principles generally accepted in the United States of America.  

The  accompanying  consolidated  financial  statements  have  been  prepared  assuming  the  Company  will  continue  as  a  going  concern.  As 
described  in Note  1 to  the consolidated financial statements,  the  Company  has incurred  recurring  operating  losses  and  has had negative cash 
flows from operations since inception. Although the Company has cash and cash equivalents of $369,581 at March 31, 2014, management has 
estimated that cash on hand, which include proceeds from convertible bridge notes received in the fourth quarter of fiscal 2014, will only be 
sufficient to allow the Company to continue its operations into the second quarter of fiscal 2015. These matters raise substantial doubt about the 
Company’s ability to continue as a going concern. Management’s plans in regard to these matters are also described in Note 1. The consolidated 
financial statements do not include any adjustments that might result from the outcome of this uncertainty.  

/s/ KMJ Corbin & Company LLP  

Costa Mesa, California  
June 25, 2014  

F- 2 

   
   
   
   
   
   
   
   
   
  
Cryoport, Inc. and Subsidiary  
Consolidated Balance Sheets  

Current Assets: 

ASSETS 

Cash and cash equivalents 
Accounts receivable, net of allowance for doubtful accounts of $24,600 and $8,700, respectively    
Inventories 
Other current assets 

   $ 

Total current assets 
Property and equipment, net 
Intangible assets, net 
Deposits and other assets 

Total assets 

Current Liabilities: 

LIABILITIES AND STOCKHOLDERS’ DEFICIT 

Accounts payable and other accrued expenses 
Accrued compensation and related expenses 
Convertible debentures payable and accrued interest, net of discount of $184,750 in 2014 
Current portion of related party notes payable 
Derivative liabilities 

Total current liabilities 

Related party notes payable and accrued interest, net of current portion 

Total liabilities 
Commitments and contingencies 
Stockholders’ (Deficit) Equity: 

   $ 

   $ 

March 31,  

2014  

2013  

369,581      $ 
515,825     
29,703     
196,505     
1,111,614     
408,892     
180,086     
9,358     
1,709,950      $ 

579,678      $ 
454,288     
1,622,359     
1,358,120     
—    
4,014,445     
—    
4,014,445     

563,104   
217,097   
39,212   
138,892   
958,305   
505,485   
272,263   
19,744   
1,755,797   

858,709   
217,432   
1,304,419   
96,000   
20,848   
2,497,408   
1,321,664   
3,819,072   

Preferred stock, $0.001 par value; 2,500,000 shares authorized; no shares issued and outstanding    
Common stock, $0.001 par value; 250,000,000 shares authorized; 59,979,954 and 37,760,628 

—    

—  

issued and outstanding at March 31, 2014 and 2013, respectively 

Additional paid-in capital 
Accumulated deficit 

Total stockholders’ deficit 

Total liabilities and stockholders’ deficit 

59,980     
83,512,399     
(85,876,874 )   
(2,304,495 )   
1,709,950      $ 

37,761   
64,210,412   
(66,311,448 ) 
(2,063,275 ) 
1,755,797   

   $ 

See accompanying notes to consolidated financial statements.  

F- 3 

   
   
   
   
  
  
  
  
  
  
    
  
  
  
  
  
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
      
  
    
  
  
      
  
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
      
  
    
  
  
      
  
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
Cryoport, Inc. and Subsidiary  
Consolidated Statements of Operations  

Revenues 
Cost of revenues 
Gross margin (loss) 

Operating costs and expenses: 

Selling, general and administrative 
Research and development 

Total operating costs and expenses 
Loss from operations 
Other (expense) income: 

Debt conversion expense 
Interest expense 
Other expense, net 
Change in fair value of derivatives 
Loss before provision for income taxes 
Provision for income taxes 
Net loss 
Net loss per common share – basic and diluted 
Weighted average shares outstanding – basic and diluted 

   $ 

Years Ended March 31, 

2014  
2,659,943      $ 
2,222,988     
436,955     

2013  
1,100,539   
1,587,823   
(487,284 ) 

5,106,219     
409,111     
5,515,330     
(5,078,375 )   

(13,713,767 )   
(784,454 )   
(8,078 )   
20,848     
(19,563,826 )   
(1,600 )   
(19,565,426 )    $ 
(0.40 )    $ 

48,850,513     

5,411,728   
425,446   
5,837,174   
(6,324,458 ) 

—  
(72,861 ) 
—  
16,486   
(6,380,833 ) 
(1,600 ) 
(6,382,433 ) 
(0.17 ) 
37,760,628   

   $ 
   $ 

See accompanying notes to consolidated financial statements.  

F- 4 

   
   
   
   
  
  
  
  
  
  
    
  
  
  
  
  
  
  
  
  
  
    
  
  
    
  
  
      
  
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
      
  
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
Cryoport, Inc. and Subsidiary  
Consolidated Statements of Stockholders’ (Deficit) Equity  

Preferred Stock 

Common Stock 

Shares 

      Amount       

      Amount       

Shares 
—         37,760,628       $ 
—        
—        

      Additional       Accumulated       Stockholders’  

Total 

Paid-

In Capital       

Deficit 

37,761       $ 63,620,774       $ (59,929,015 )    $ 
(6,382,433 )      

—        

—        

(Deficit)  
Equity  
3,729,520   
(6,382,433 ) 

Balance at March 31, 2012 

Net loss 
Offering costs in connection with the  

February 2012 private placement offering 

Stock-based compensation expense 

Balance at March 31, 2013 

Net loss 
Stock-based compensation expense 
Estimated relative fair value of warrants issued in connection 

with convertible bridge notes payable 

Issuance of common stock upon exercise of options and 

warrants 

Issuance of common stock units upon conversion of 

convertible bridge notes and accrued interest 

Induced debt conversion expense 

Balance at March 31, 2014 

—      $ 
—        

—        
—        

—        
—        
—        

—        

—        

—        
—        
—      $ 

—        
—        

—        
—        

—        
—        

(103,542 )      
693,180         

—        
—        

(103,542 ) 
693,180   

—         37,760,628         
—        
—        
—        
—        

37,761          64,210,412          (66,311,448 )      

(2,063,275 ) 
—         (19,565,426 )       (19,565,426 ) 
678,119   

—        

678,119         

—        
—        

—        

—        

—        

478,229         

—        

478,229   

—         1,583,315         

1,583         

325,307         

—        

326,890   

—         20,636,011         
—        
—        
—         59,979,954       $ 

20,636          4,106,565         
—         13,713,767         

59,980       $ 83,512,399       $ (85,876,874 )    $ 

—        
4,127,201   
—         13,713,767   
(2,304,495 ) 

See accompanying notes to consolidated financial statements.  

F- 5 

   
   
   
   
  
  
     
        
        
        
        
        
     
  
  
  
     
  
  
     
  
     
     
     
     
  
     
          
          
          
          
          
          
    
     
     
     
     
     
     
     
     
Cryoport, Inc. and Subsidiary  

Consolidated Statements of Cash Flows  

Cash Flows From Operating Activities: 

Net loss 
Adjustments to reconcile net loss to net cash used in operating activities: 

Depreciation and amortization 
Amortization of debt discount and deferred financing costs 
Stock-based compensation expense 
Change in fair value of derivative instruments 
Loss on write-off of intangible assets 
Loss on disposal of cryogenic shippers 
Reserve for bad debt 
Debt conversion expense 
Changes in operating assets and liabilities: 

Accounts receivable, net 
Inventories 
Other assets 
Accounts payable and other accrued expenses 
Accrued compensation and related expenses 
Accrued interest 

Net cash used in operating activities 

Cash Flows From Investing Activities: 

Purchases of intangible assets 
Purchases of property and equipment 

Net cash used in investing activities 

Cash Flows From Financing Activities: 

Proceeds from exercise of stock options and warrants 
Proceeds from issuance of convertible debt 
Repayment of convertible debt 
Repayment of offering and deferred financing costs 
Repayment of related party notes payable 

Net cash provided by financing activities 

Net decrease in cash and cash equivalents 

Cash and cash equivalents — beginning of year 
Cash and cash equivalents — end of year 
Supplemental Disclosure of Cash Flow Information: 

Cash paid for interest 
Cash paid for income taxes 

Supplemental Disclosure of Non-Cash Investing and Financing Activities: 

Offering costs in connection with equity financing included in accounts payable 
Deferred financing costs in connection with convertible debt payable included in accounts 
payable 
Release of restricted cash for repayment of convertible debentures 
Estimated relative fair value of warrants issued in connection with convertible bridge notes 
payable 
Conversion of bridge notes payable and accrued interest into common stock units 

   $ 

   $ 
   $ 

   $ 
   $ 

See accompanying notes to consolidated financial statements.    

F- 6 

Years Ended March 31, 
2013 
2014 

   $ 

(19,565,426 )    $ 

(6,382,433 ) 

311,590     
678,915     
678,119     
(20,848 )   
—    
16,066     
24,876     
13,713,767     

(323,604 )   
9,509     
(26,588 )   
(221,929 )   
236,856     
108,038     
(4,380,659 )   

393,959   
17,514   
693,180   
(16,486 ) 
17,046   
51,033   
—  
—  

(70,973 ) 
12,542   
34,912   
443,568   
(18,564 ) 
39,558   
(4,785,144 ) 

—    
(138,886 )   
(138,886 )   

(22,482 ) 
(156,200 ) 
(178,682 ) 

326,890     
4,558,301     
—    
(463,169 )   
(96,000 )   
4,326,022     
(193,523 )   
563,104     
369,581      $ 

—  
1,294,500   
(82,800 ) 
(206,305 ) 
(96,000 ) 
909,395   
(4,054,431 ) 
4,617,535   
563,104   

—     $ 
1,600      $ 

15,676   
1,600   

—     $ 

53,747   

30,120      $ 
—     $ 

38,475   
251,368   

478,229      $ 
4,127,201      $ 

—  
—  

   $ 

   $ 
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Note 1. Nature of the Business  

Cryoport, Inc. and Subsidiary  
Notes to Consolidated Financial Statements  

Cryoport Inc. (the “Company”, “Cryoport” or “we”) is a Nevada corporation originally incorporated under the name G.T.5-Limited 

(“GT5”) on May 25, 1990. In connection with a Share Exchange Agreement, on March 15, 2005 we changed our name to Cryoport, Inc. and 
acquired all of the issued and outstanding shares of common stock of Cryoport Systems, Inc., a California corporation, in exchange for 
2,410,811 shares of our common stock (which represented approximately 81% of the total issued and outstanding shares of common stock 
following the close of the transaction). Cryoport Systems, Inc., which was originally formed in 1999 as a California limited liability company, 
and subsequently reorganized into a California corporation on December 11, 2000, remains the operating company under Cryoport, Inc. We 
became “publicly held” by the reverse merger with GT5 described above. Over time we have transitioned from being a development company to 
a fully operational public company, providing cold chain logistics solutions to the biotechnology and life sciences industries, globally.  

Through a combination of purpose-built proprietary packaging, information technologies and specialized logistics knowhow, we provide 
frozen shipping logistics solutions to the life sciences industry. We view our solutions as disruptive to “older technologies” in that our solutions 
provide reliable, economic alternatives to existing solutions and services utilized for frozen shipping in life sciences including stem cells, cell 
lines, vaccines, diagnostic materials, semen, eggs, embryos, cord blood, bio-pharmaceuticals, infectious substances and other items that require 
continuous exposure to frozen or cryogenic temperatures.  

Our Cryoport Express ® Solutions includes sophisticated cloud-based logistics management software we have branded as the Cryoportal™ 

which supports the management of the entire shipment process through a single interface, including initial order input, document preparation, 
customs clearance, courier management, shipment tracking, issue resolution, and delivery. The Cryoportal™ provides unique and incisive 
information dashboards and validation documentation for every shipment. The Cryoportal™ records and retains a fully documented “chain-of-
custody” and, at the client’s option, “chain-of-condition” for every shipment, helping ensure that quality, safety, efficacy, and stability of shipped 
commodities are maintained throughout the process. This recorded and archived information allows our customers to meet exacting requirements 
necessary for scientific work and for regulatory purposes.  

Our Cryoport Express ® Solutions also includes our liquid nitrogen dry vapor shippers we have branded as our Cryoport Express ® 

Shippers, which are cost-effective and reusable cryogenic transport containers (patented vacuum flasks) utilizing innovative liquid nitrogen 
(“LN2”) “dry vapor” technology. Cryoport Express ® Shippers are International Air Transport Association (“IATA”) certified, and validated to 
maintain stable temperatures of minus 150° C and below for a 10-plus day dynamic shipment period. The Company currently features two 
Cryoport Express ® Shipper models, the Standard Dry Shipper (holding up to 75-2.0 ml vials) and the High Volume Dry Shipper (holding up to 
500-2.0 ml vials).  

Amongst our solutions, we offer a “turnkey” solution, which can be accessed through our cloud-based Cryoportal™ or by contacting 

Cryoport Client Care for order entry. Once the order is placed, we ship a fully charged Cryoport Express® Shipper to the customer who 
conveniently loads their frozen commodity into the inner chamber of the shipper.  The customer then closes the shipper and reseals the shipping 
box displaying the recipient’s address (“Flap A”) for pre-arranged carrier pick up.  Cryoport arranges for the pick-up of the parcel by a shipping 
service provider for delivery to the customer’s intended recipient.  The recipient simply opens the box and shipper and removes the frozen 
commodity.  The recipient only needs to reseal the box, displaying the nearest Cryoport Operations Center address (“Flap B”) and set it out for 
pre-arranged carrier pick up. The Cryoport Express ® Shipper is returned to us for cleaning, quality assurance testing, recharging and reuse.  

In late 2012, we shifted our focus from being a developer of cryogenic shippers and software to being a comprehensive frozen logistics 

solutions provider to the life sciences industry, which was accomplished by broadening our service offerings. Now, in addition to our “Turn-key 
Solution”, we also provide the following value-added solutions that were developed to address our various clients’ needs:  

• 

• 

“ Customer Staged Solution ,” under which we supply an inventory of our Cryoport Express® Shippers to our customer, in an 
uncharged state, enabling our customer (after training/certification) to charge them with liquid nitrogen and use our Cryoportal™ to 
enter orders with shipping and delivery service providers for the transportation of the package. Once the order is released, our customer 
services professionals monitor the shipment and the return of the shipper to us for cleaning, quality assurance testing and reuse. 

“ Customer Managed Solution ,” a limited customer implemented, solution, whereby we supply our Cryoport Express® Shippers to 
clients in a fully charged state, but leaving it to the client to manage the shipping, including the selection of the shipping and delivery 
service provider and the return of the shipper to us. Under this solution, the customer accepts a significant level of the risk for a 
successful shipment. 

F- 7 

   
   
   
   
   
   
   
   
   
   
   
  
• 

• 

• 

• 

“ Powered by Cryoport SM ” is made available to providers of shipping and delivery services who seek to offer a “branded” cryogenic 
shipping solution as part of their service offerings. By negotiation, this solution can be private labeled as long as “ powered by Cryoport 
SM ” appears prominently on the offering software interface and prominently on the packaging, which is provided by the client after 
minimum volume requirements are met. 

“ Integrated Solution ” is our most comprehensive and complex outsourcing solution. It usually involves our management of the entire 
cryogenic logistics process for our client, including the location of our employees at the client’s site to manage the client’s cryogenic 
logistics, in total. 

“  Life  Science  Point-of-Care  Repository  Solution  ”  whereby  we  supply  our  Cryoport  Express  ®  Shippers  to  ship  and  store 
cryogenically preserved life science products for up to 6 days (or longer periods with substitute Shippers) at a point-of-care site, with 
the Cryoport Express  ® Shippers serving as a temporary freezer/repository enabling the efficient distribution of temperature sensitive 
allogeneic  cell-based  therapies  without  the  expense,  inconvenience,  and  potential  costly  failure  of  an  on-sight,  cryopreservation 
apparatus. Our customer services professionals monitor each shipment throughout the predetermined process including the shipment’s 
return  to  Cryoport  where  the  Cryoport  Express  ®  Shipper  is  cleaned,  tested  for  quality  assurance  and  then  returned  to  inventory  for 
reuse. 

“ Personalized Medicine and Cell-based Immunotherapy Solution ” whereby our Cryoport Express ® Solutions serves as an enabling 
technology for the safe manufacture of the rapidly expanding autologous cellular-based immunotherapy market by providing a 
comprehensive logistics solution for the verified chain of custody and condition transport from, (a) the collection of the patient’s cells in 
a hospital setting, to (b) a central processing facility where they are manufactured into a personalized medicine, to (c) the safe, 
cryogenically preserved return of these irreplaceable cells to a point-of-care treatment facility.  The Cryoport Express ® Shippers can 
then serve as a temporary freezer/repository to allow the efficient distribution of this personalized medicine to patients when and where 
they need it most without the expense, inconvenience, and potential costly failure of an on-sight, cryopreservation apparatus. Our 
customer services professionals monitor each shipment throughout the predetermined process including the shipment’s return to 
Cryoport where the Cryoport Express ® Shipper is cleaned, tested for quality assurance and then returned to inventory for reuse. 

One of our distribution partners is Federal Express Corporation (“FedEx”). We have an agreement with FedEx to provide frozen shipping 
logistics services through the combination of our purpose-built proprietary technologies and turnkey management processes. FedEx markets and 
sells Cryoport’s services for frozen temperature-controlled cold chain transportation as its FedEx ® Deep Frozen Shipping Solution on a non-
exclusive basis and at its sole expense. During fiscal year 2013, the Company worked closely with FedEx to further align its sales efforts and 
accelerate penetration within FedEx’s life sciences customer base through improved processes, sales incentives, joint customer calls and more 
frequent communication at the sales and executive level. In addition, FedEx has developed a FedEx branded version of the Cryoportal TM 
software platform, which is “ powered by Cryoport ” for use by FedEx and its customers giving them access to the full capabilities of our 
logistics management platform.  

In January 2013, we entered into a master agreement (“FedEx Agreement”) with FedEx renewing these services and providing FedEx with 
a non-exclusive license and right to use a customized version of our Cryoportal TM for the management of shipments made by FedEx customers. 
The FedEx Agreement became effective on January 1, 2013 and, unless sooner terminated as provided in the FedEx Agreement, expires on 
December 31, 2015.  

Pursuant to an agreement with DHL Express (USA), Inc. (“DHL”), DHL biotechnology and life science customers have direct access to 
our cloud-based order entry and tracking portal to order Cryoport Express ® Shippers and receive preferred DHL shipping rates. The agreement 
covers DHL shipping discounts that may be used to support our customers using our Cryoport Express ® Solutions. In connection with the 
agreement, we have integrated our proprietary Cryoportal TM to DHL’s tracking and billing systems to provide DHL biotechnology and life 
science customers with a seamless way (“ powered by Cryoport ”) of shipping their critical biological material worldwide.  

In December 2012, we signed an agreement with Pfizer Inc. relating to Zoetis Inc. (formerly the animal health business unit of Pfizer Inc.) 

pursuant to which we were engaged to manage frozen shipments of a key poultry vaccine. Under this arrangement, the Company is providing 
on-site logistics personnel and its logistics management platform, the Cryoportal TM , to manage shipments from the Zoetis manufacturing site in 
the United States to domestic customers as well as various international distribution centers. As part of our logistics management services, 
Cryoport is constantly analyzing shipping data and processes to further streamline Zoetis’ logistics, ensuring products arrive at their destinations 
in specified conditions, on-time and with the optimum uses of resources. The Company manages Zoetis’ total fleet of dewar flask shippers used 
for this purpose, including liquid nitrogen shippers. In July 2013 the agreement was amended to expand Cryoport’s scope to manage all logistics 
of Zoetis’ key frozen poultry vaccine to all Zoetis’ international distribution centers as well as all domestic shipments of this vaccine. In October 
2013, the agreement was further amended to further expand Cryoport’s services to include the logistics management for a second poultry 
vaccine.  

F- 8 

   
   
   
   
   
   
   
    
   
  
In February 2014, we entered into a services agreement with Liventa Bioscience, Inc. (“Liventa”), a privately-held, commercial stage 

biotechnology company focused on cell-based, advanced biologics in the orthopedic industry. Under this agreement, Liventa will be using 
Cryoport Express ® Solutions for the logistics of its cell-based therapies requiring cryogenic temperatures and also provide Cryoport Express ® 
Solutions to other biologics suppliers within the orthopedic arena. The agreement combines Cryoport’s proprietary, purpose-built cold chain 
logistics solutions for cell-based and advanced biologic tissue forms with Liventa’s distribution capability to orthopedic care providers. The 
implementation of Cryoport’s solution will eliminate dry ice shipping and related risks of degradation and also eliminate the need for expensive 
onsite cryogenic freezers for storage of cell-based orthopedic therapies. This will enable Liventa to better serve small or mobile clinics, 
pharmacies, family practice, and orthopedic specialty care providers. Surgical centers and hospitals will also benefit from better logistics and the 
elimination of issues surrounding dry ice transport and storage. The agreement has an initial three-year term and may be renewed for consecutive 
three-year terms. Liventa also agreed to certain performance criteria and the issuance of 150,000 shares of its common stock to Cryoport in 
exchange for the exclusive right to offer, market and promote Cryoport Express ® Solutions for cellular-based therapies requiring cryogenic 
temperatures for use  
in orthopedic indications in the United States.  

We offer our solutions to companies in the life sciences industry and specific verticals including manufacturers of stem cells and cell lines, 

diagnostic laboratories, bio-pharmaceuticals, contract research organizations, in-vitro fertilization, cord blood, vaccines, tissue, animal 
husbandry, and other producers of commodities requiring reliable frozen solutions for logistics problems. These companies operate within 
heavily regulated environments and as such, changing vendors and distribution practices typically require a number of steps which may include 
the audit of our facilities, review of our procedures, qualifying us as a vendor, and performing test shipments. This process can take up to nine 
months or longer to complete prior to a potential customer adopting one or more of the Cryoport Express ® Solutions.  

Going Concern  

The consolidated financial statements have been prepared using the accrual method of accounting in accordance with accounting principles 

generally accepted in the United States of America (“U.S. GAAP”) and have been prepared on a going concern basis, which contemplates the 
realization of assets and the settlement of liabilities in the normal course of business. We have sustained operating losses since our inception and 
have used substantial amounts of working capital in our operations. Further, at March 31, 2014, we had an accumulated deficit of $85.9 million. 
During the year ended March 31, 2014, we used cash in operations of $4.4 million and had a net loss of $19.6 million, which included a one-
time, non-cash debt conversion expense of $13.7 million.  

We expect to continue to incur substantial additional operating losses from costs related to the commercialization of our Cryoport Express 

® Solutions and do not expect that revenues from operations will be sufficient to satisfy our funding requirements in the near term. We believe 
that our cash resources at March 31, 2014, additional funds raised subsequent to March 31, 2014 through the current preferred stock offering (see 
Note 15), together with the revenues generated from our services will be sufficient to sustain our planned operations into the second quarter of 
fiscal year 2015; however, we must obtain additional capital to fund operations thereafter and for the achievement of sustained profitable 
operations. These factors raise substantial doubt about our ability to continue as a going concern. We are currently working on funding 
alternatives in order to secure sufficient operating capital to allow us to continue to operate as a going concern.  

Future capital requirements will depend upon many factors, including the success of our commercialization efforts and the level of 
customer adoption of our Cryoport Express ® Solutions as well as our ability to establish additional collaborative arrangements. We cannot make 
any assurances that the sales ramp will lead to achievement of sustained profitable operations or that any additional financing will be completed 
on a timely basis and on acceptable terms or at all. Management’s inability to successfully achieve significant revenue increases or implement 
cost reduction strategies or to complete any other financing will adversely impact our ability to continue as a going concern. To address this 
issue, the Company is seeking additional capitalization to properly fund our efforts to become a self-sustaining financially viable entity.  

Note 2. Summary of Significant Accounting Policies  

Basis of Presentation  

The accompanying consolidated financial statements have been prepared in accordance with U.S. GAAP.  

F- 9 

   
   
   
   
   
   
   
   
   
   
  
Principles of Consolidation  

The consolidated financial statements include the accounts of Cryoport, Inc. and its wholly owned subsidiary, Cryoport Systems, Inc. All 

intercompany accounts and transactions have been eliminated.  

Use of Estimates  

The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that 

affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and 
the reported amounts of revenues and expenses during the reporting periods. Actual results could differ from estimated amounts. The Company’s 
significant estimates include allowances for doubtful accounts, recoverability of long-lived assets, allowance for inventory obsolescence, 
deferred taxes and their accompanying valuations, valuation of derivative liabilities and valuation of common stock, warrants and stock options 
issued for products or services.  

Fair Value of Financial Instruments  

The Company’s financial instruments consist of cash and cash equivalents, accounts receivable, related-party notes payable, convertible 
notes payable, accounts payable and accrued expenses. The carrying value for all such instruments approximates fair value at March 31, 2014 
and 2013 due to their short-term nature. The difference between the fair value and recorded values of the related party notes payable is not 
significant.  

Cash and Cash Equivalents  

The Company considers highly liquid investments with original maturities of 90 days or less to be cash equivalents.  

Concentrations of Credit Risk  

The Company maintains its cash accounts in financial institutions. Accounts at these institutions are insured by the Federal Deposit 
Insurance Corporation (“FDIC”) with basic deposit insurance coverage limits up to $250,000 per owner. At March 31, 2014 and 2013, the 
Company had cash balances of approximately $159,000 and $214,000, respectively, which exceeded the FDIC insurance limit. The Company 
performs ongoing evaluations of these institutions to limit its concentration risk exposure.  

Customers  

The Company grants credit to customers within the U.S. and to a limited number of international customers and does not require collateral. 
Revenues from international customers are generally secured by advance payments except for a limited number of established foreign customers. 
The Company generally requires advance or credit card payments for initial revenues from new customers. The Company’s ability to collect 
receivables is affected by economic fluctuations in the geographic areas and industries served by the Company. Reserves for uncollectible 
amounts are provided based on past experience and a specific analysis of the accounts, which management believes is sufficient. Accounts 
receivable at March 31, 2014 and 2013 are net of reserves for doubtful accounts of $24,600 and $8,700, respectively. Although the Company 
expects to collect amounts due, actual collections may differ from the estimated amounts.  

The majority of the Company’s customers are in the biotechnology, pharmaceutical and life science industries. Consequently, there is a 

concentration of accounts receivable within these industries, which is subject to normal credit risk. At March 31, 2014, there was one customer 
that accounted for 30.6% of net accounts receivable. No other single customer owed us more than 10% of net accounts receivable at March 31, 
2014 and 2013. The Company maintains reserves for bad debt and such losses, in the aggregate, historically have not exceeded our estimates.  

The Company has revenue from foreign customers primarily in Europe, Japan, Canada, India and Australia. During fiscal years 2014 and 

2013, the Company had revenues from foreign customers of approximately $434,000 and $161,000, respectively, which constituted 
approximately 16.3% and 14.6% of total revenues, respectively. For the fiscal year ended March 31, 2014, there was one customer that 
accounted for 30.8% of net revenues. No other single customer generated over 10% of net revenues during 2014 and 2013.  

Inventories  

The Company’s inventories consist of accessories that are sold and shipped to customers along with pay-per-use containers that are not 
returned to the Company with the containers at the culmination of the customer’s shipping cycle. Inventories are stated at the lower of cost or 
current estimated market value. Cost is determined using the standard cost method which approximates the first-in, first-to-expire method. 
Inventories are reviewed periodically for slow-moving or obsolete status. The Company writes down the carrying value of its inventories to 
reflect situations in which the cost of inventories is not expected to be recovered. Once established, write-downs of inventories are considered 
permanent adjustments to the cost basis of the obsolete or excess inventories. Raw materials and finished goods include material costs less 
reserves for obsolete or excess inventories. The Company evaluates the current level of inventories considering historical trends and other 
factors, and based on the evaluation, records adjustments to reflect inventories at its net realizable value. These adjustments are estimates, which 
could vary significantly from actual results if future economic conditions, customer demand, competition or other relevant factors differ from 
expectations. These estimates require us to make assessments about future demand for the Company’s products in order to categorize the status 
of such inventories items as slow-moving, obsolete or in excess-of-need. These estimates are subject to the ongoing accuracy of the Company’s 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
forecasts of market conditions, industry trends, competition and other factors.  

F- 10 

   
Property and Equipment  

The Company provides shipping containers to its customers and charges a fee in exchange for the use of the container. The Company’s 

arrangements are similar to the accounting standard for leases since they convey the right to use the container over a period of time. The 
Company retains the title to the containers and provides its customers the use of the container for a specific shipping cycle. At the culmination of 
the customer’s shipping cycle, the container is returned to the Company. As a result, the Company classifies the containers as fixed assets for the 
per-use container program.  

Property and equipment are recorded at cost. Cryogenic shippers, which comprise of 89% and 87% of the Company’s net property and 

equipment balance at March 31, 2014 and 2013, respectively, are depreciated using the straight-line method over their estimated useful lives of 
three years. Equipment and furniture are depreciated using the straight-line method over their estimated useful lives (generally three to seven 
years) and leasehold improvements are amortized using the straight-line method over the estimated useful life of the asset or the lease term, 
whichever is shorter. Equipment acquired under capital leases is amortized over the estimated useful life of the assets or term of the lease, 
whichever is shorter and included in depreciation expense.  

Betterments, renewals and extraordinary repairs that extend the lives of the assets are capitalized; other repairs and maintenance charges 

are expensed as incurred. The cost and related accumulated depreciation and amortization applicable to assets retired are removed from the 
accounts, and the gain or loss on disposition is recognized in current operations.  

Intangible Assets  

Intangible assets are comprised of patents and trademarks and software development costs. The Company capitalizes costs of obtaining 

patents and trademarks, which are amortized, using the straight-line method over their estimated useful life of five years. The Company 
capitalizes certain costs related to software developed for internal use. Software development costs incurred during the preliminary or 
maintenance project stages are expensed as incurred, while costs incurred during the application development stage are capitalized and amortized 
using the straight-line method over the estimated useful life of the software, which is five years. Capitalized costs include purchased materials 
and costs of services including the valuation of warrants issued to consultants.  

Long-lived Assets  

If indicators of impairment exist, we assess the recoverability of the affected long-lived assets by determining whether the carrying value 

of such assets can be recovered through undiscounted future operating cash flows. If impairment is indicated, we measure the amount of such 
impairment by comparing the fair value to the carrying value. We believe the future cash flows to be received from the long-lived assets will 
exceed the assets’ carrying value, and accordingly, we have not recognized any impairment losses through March 31, 2014.  

Deferred Financing Costs  

Deferred financing costs represent costs incurred in connection with the issuance of the convertible notes payable and private equity 
financing. Deferred financing costs related to the issuance of debt are being amortized over the term of the financing instrument using the 
effective interest method while deferred financing costs from equity financings are netted against the gross proceeds received from the equity 
financings.  

In connection with the 5% Bridge Notes, during the third and fourth quarter of fiscal 2014, the Company incurred financing costs that have 

been capitalized and are being amortized over the term of the convertible bridge notes payable using the straight-line method which 
approximates the effective interest method (see Note 8).  

F- 11 

   
   
   
   
   
   
   
   
   
   
   
   
  
During the year ended March 31, 2013, the Company incurred $103,542 of offering costs in connection with the private placement that 

closed in February and March 2012, which were charged to additional paid-in capital and netted against the proceeds received in the private 
placements. As of March 31, 2013, offering costs of $53,747 related to the private placement were included in accounts payable and accrued 
expenses in the accompanying consolidated balance sheet.  

Convertible Debentures  

If a conversion feature of conventional convertible debt is not accounted for as a derivative instrument and provides for a rate of 

conversion that is below market value, this feature is characterized as a beneficial conversion feature (“BCF”). A BCF is recorded by the 
Company as a debt discount. The convertible debt is recorded net of the discount related to the BCF. The Company amortizes the discount to 
interest expense over the life of the debt using the effective interest rate method.  

Derivative Liabilities  

Certain of the Company’s issued and outstanding common stock purchase warrants which have exercise price reset features are treated as 
derivatives for accounting purposes. The common stock purchase warrants were not issued with the intent of effectively hedging any future cash 
flow, fair value of any asset, liability or any net investment in a foreign operation. The warrants do not qualify for hedge accounting, and as such, 
all future changes in the fair value of these warrants are recognized currently in earnings until such time as the warrants are exercised, expire or 
the related rights have been waived. These common stock purchase warrants do not trade in an active securities market, and as such, the 
Company estimates the fair value of these warrants using the Black-Scholes option pricing model (“Black-Scholes”) (see Note 9).  

Income Taxes  

The Company accounts for income taxes under the provision of the Financial Accounting Standards Board (“FASB”) Accounting 
Standards Codification (“ASC”) 740, Income Taxes , or ASC 740. As of March 31, 2014 and 2013, there were no unrecognized tax benefits 
included in the accompanying consolidated balance sheets that would, if recognized, affect the effective tax rates.  

Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those 

temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is 
recognized in income in the period that includes the enactment date. A valuation allowance is provided for certain deferred tax assets if it is more 
likely than not that the Company will not realize tax assets through future operations. Based on the weight of available evidence, the Company’s 
management has determined that it is more likely than not that the net deferred tax assets will not be realized. Therefore, the Company has 
recorded a full valuation allowance against the net deferred tax assets. The Company’s income tax provision consists of state minimum taxes.  

The Company’s policy is to recognize interest and/or penalties related to income tax matters in income tax expense. The Company had no 

accrual for interest or penalties on its consolidated balance sheets at March 31, 2014 and 2013, respectively and has not recognized interest 
and/or penalties in the consolidated statement of operations for the years ended March 31, 2014 and 2013. The Company is subject to taxation in 
the U.S. and various state jurisdictions. As of March 31, 2014, the Company is no longer subject to U.S. federal examinations for years before 
2010 and for California franchise and income tax examinations for years before 2009. However, to the extent allowed by law, the taxing 
authorities may have the right to examine prior periods where net operating losses were generated and carried forward, and make adjustments up 
to the amount of the net operating loss carry forward amount. The Company is not currently under examination by U.S. federal or state 
jurisdictions.  

Revenue Recognition  

The Company provides shipping containers to its customers and charges a fee in exchange for the use of the container. The Company’s 

arrangements are similar to the accounting standard for leases since they convey the right to use the containers over a period of time. The 
Company retains title to the containers and provides its customers the use of the container for a specified shipping cycle. At the culmination of 
the customer’s shipping cycle, the container is returned to the Company.  

The Company recognizes revenue for the use of the shipper at the time of the delivery of the shipper to the end user of the enclosed 

materials, and at the time that collectability is reasonably certain. Revenue is based on gross net of discounts and allowances.  

The Company also provides logistics support and management to some customers, which may include onsite logistics personnel. Revenue 

is recognized for these services as services are rendered and at the time that collectability is reasonably certain.  

F- 12 

   
   
   
   
   
   
   
   
   
    
   
   
   
   
  
Accounting for Shipping and Handling Revenue, Fees and Costs  

The Company classifies amounts billed for shipping and handling as revenue. Shipping and handling fees and costs are included in cost of 

revenues in the accompanying consolidated statements of operations.  

Research and Development Expenses  

Expenditures relating to research and development are expensed in the period incurred.  

Stock-based Compensation  

The Company accounts for stock-based payments to employees and directors in accordance with stock-based payment accounting 
guidance which requires all stock-based payments to employees and directors, including grants of employee stock options and warrants, to be 
recognized based upon their fair values. The fair value of stock-based awards is estimated at grant date using Black-Scholes and the portion that 
is ultimately expected to vest is recognized as compensation cost over the requisite service period.  

Since stock-based compensation is recognized only for those awards that are ultimately expected to vest, the Company has applied an 

estimated forfeiture rate to unvested awards for the purpose of calculating compensation cost. These estimates will be revised, if necessary, in 
future periods if actual forfeitures differ from estimates. Changes in forfeiture estimates impact compensation cost in the period in which the 
change in estimate occurs. The estimated forfeiture rates at March 31, 2014 and 2013 was zero as the Company has not had a significant history 
of forfeitures and does not expect significant forfeitures in the future.  

Cash flows from the tax benefits resulting from tax deductions in excess of the compensation cost recognized for those options or warrants 

are classified as financing cash flows. Due to the Company’s loss position, there were no such tax benefits during years ended March 31, 2014 
and 2013.  

The Company uses Black-Scholes to estimate the fair value of stock-based awards. The determination of fair value using Black-Scholes is 
affected by the Company’s stock price as well as assumptions regarding a number of complex and subjective variables, including expected stock 
price volatility, risk-free interest rate, expected dividends and projected employee stock option exercise behaviors.  

The Company’s stock-based compensation plans are discussed further in Note 12.  

Equity Instruments Issued to Non-Employees for Acquiring Goods or Services  

Issuances of the Company’s common stock for acquiring goods or services are measured at the fair value of the consideration received or 

the fair value of the equity instruments issued, whichever is more reliably measurable. The measurement date for the fair value of the equity 
instruments issued to consultants or vendors is determined at the earlier of (i) the date at which a commitment for performance to earn the equity 
instruments is reached (a “performance commitment” which would include a penalty considered to be of a magnitude that is a sufficiently large 
disincentive for nonperformance) or (ii) the date at which performance is complete. When it is appropriate for the Company to recognize the cost 
of a transaction during financial reporting periods prior to the measurement date, for purposes of recognition of costs during those periods, the 
equity instrument is measured at the then-current fair values at each of those interim financial reporting dates.  

Basic and Diluted Net Income (Loss) Per Share  

We calculate basic and diluted net income (loss) per share using the weighted average number of common shares outstanding during the 
periods presented, and adjust the amount of net income (loss) used in this calculation for preferred stock dividends (if any) declared during the 
period. In periods of a net loss position, basic and diluted weighted average shares are the same. For the diluted earnings per share calculation, 
we  adjust  the  weighted  average  number  of  common  shares  outstanding  to  include  dilutive  stock  options,  warrants  and  other  common  stock 
equivalents outstanding during the periods.  

The following shows the amounts used in computing net loss per share for each of the two years in the period ended March 31, 2014:  

Net loss  
Less: 
Preferred dividends paid in cash or stock 
Loss attributable to Cryoport stockholders 
Weighted average shares issued and outstanding 
Basic and diluted net loss per share 

F- 13 

Years Ended March 31, 
2013 
2014 
(6,382,433 ) 

(19,565,426 )    $ 

—    

(19,565,426 )    $ 
48,850,513     

(0.40 )    $ 

—  
(6,382,433 ) 
37,760,628   
(0.17 ) 

   $ 

   $ 

   $ 

   
   
   
   
   
   
   
   
   
   
   
   
     
   
   
   
   
  
    
  
  
  
    
  
  
  
      
  
    
  
  
  
  
  
  
The following table sets forth the number of shares excluded from the computation of diluted earnings per share, as their inclusion would 

have been anti-dilutive:  

Stock options 
Warrants 

Segment Reporting  

Years Ended March 31, 
2014 
2013 
3,458,313       
3,221,728       
6,680,041     

411,762   
—  
411,762   

We currently operate in one reportable segment.  

Fair Value Measurements  

We measure fair value based on the prices that would be received to sell an asset or paid to transfer a liability in an orderly transaction 
between market participants at the measurement date. Fair value measurements are based on a three-tier hierarchy that prioritizes the inputs used 
to measure fair value. These tiers include the following:  

Level 1:  Quoted prices (unadjusted) in active markets for identical assets or liabilities that are accessible at the measurement date. The fair 

value hierarchy gives the highest priority to Level 1 inputs.  

Level 2:  Observable prices that are based on inputs not quoted on active markets, but corroborated by market data. These inputs include 

quoted prices for similar assets or liabilities; quoted market prices in markets that are not active; or other inputs that are observable or can be 
corroborated by observable market data for substantially the full term of the assets or liabilities. Currently we do not have any items classified as 
Level 2.  

Level 3:  Unobservable inputs are used when little or no market data is available. The fair value hierarchy gives the lowest priority to 

Level 3 inputs.  

 In determining fair value, we utilize valuation techniques that maximize the use of observable inputs and minimize the use of 

unobservable inputs to the extent possible, as well as consider counterparty credit risk in the assessment of fair value.  

We did not elect the fair value option, as allowed, to account for financial assets and liabilities that were not previously carried at fair 
value. Therefore, material financial assets and liabilities that are not carried at fair value, such as trade accounts receivable and payable, are 
reported at their historical carrying values.  

The carrying values of our assets and liabilities that are required to be measured at fair value on a recurring basis as of March 31, 2014 and 

2013 are classified in the table below in one of the three categories of the fair value hierarchy described below:  

March 31, 2013 
Liabilities: 

Derivative liabilities 

Fair Value Measurements 

   Level 1       Level 2       Level 3       Total 

  $ 

—    $ 

—    $  20,848     $  20,848   

F- 14 

   
   
   
   
   
   
   
   
   
   
   
   
  
    
  
  
  
    
  
    
    
  
  
  
  
  
  
  
    
      
      
      
  
    
      
      
      
  
The following summarizes the activity of Level 3 inputs measured on a recurring basis for the years ended March 31, 2014 and 2013:    

Balance at March 31, 2012 

Transfers in / (out) of Level 3 
Adjustments resulting from a change in fair value of derivative liabilities 

Balance at March 31, 2013 

Transfers in / (out) of Level 3 
Adjustments resulting from a change in fair value of derivative liabilities 

Balance at March 31, 2014 

Fair Value Measurements 
of  Unobservable Inputs 
(Level 3) 

  $ 

  $ 

37,334   
—  
(16,486 ) 
20,848   
—  
(20,848 ) 
—  

The fair value of derivative liabilities were measured on their respective origination dates and at the end of each reporting period using 
Level 3 inputs. The significant assumptions we use in the calculations under Black-Scholes as of March 31, 2014 and 2013 included an expected 
term  based  on  the  remaining  contractual  life  of  the  warrants,  a  risk-free  interest  rate  based  upon  observed  interest  rates  appropriate  for  the 
expected term of the instruments, volatility based on the historical volatility of our common stock, and a zero dividend rate based on our past, 
current and expected practices of granting dividends on common stock.  

Foreign Currency Translation  

We record foreign currency transactions at the exchange rate prevailing at the date of the transaction with resultant gains and losses being 

included in results of operations. Foreign currency transaction gains and losses have not been significant for any of the periods presented.  

Recent Accounting Pronouncements  

In July 2013, the FASB issued ASU No. 2013-11, “Presentation of an Unrecognized Tax Benefit When a Net Operating Loss 
Carryforward, a Similar Tax Loss, or a Tax Credit Carryforward Exists.” ASU 2013-11 provides explicit guidance on the financial statement 
presentation of an unrecognized tax benefit when a net operating loss carryforward, a similar tax loss, or a tax credit carryforward exists. The 
guidance is effective prospectively for fiscal years, and interim periods within those years, beginning after December 15, 2013, with an option 
for early adoption. This pronouncement is effective for reporting periods beginning on or after January 1, 2013. The adoption of ASU 2011-11 
did not have a material impact on the Company’s consolidated financial statements.  

In May 2014, the FASB issued ASU No. 2014-09, “Revenue from Contracts with Customers”. ASU 2014-09 supersedes the revenue 

recognition requirements in FASB Topic 605, "Revenue Recognition". The ASU implements a five-step process for customer contract revenue 
recognition that focuses on transfer of control, as opposed to transfer of risk and rewards. The amendment also requires enhanced disclosures 
regarding the nature, amount, timing and uncertainty of revenues and cash flows from contracts with customers. Other major provisions include 
the capitalization and amortization of certain contract costs, ensuring the time value of money is considered in the transaction price, and allowing 
estimates of variable consideration to be recognized before contingencies are resolved in certain circumstances. The amendments in this ASU are 
effective for reporting periods beginning after December 15, 2016, and early adoption is prohibited. Entities can transition to the standard either 
retrospectively or as a cumulative-effect adjustment as of the date of adoption. Management is currently assessing the impact the adoption of 
ASU 2014-09 will have on our consolidated financial statements.  

Note 3. Inventories  

Inventories consist of the following:  

Raw materials 
Finished goods 

March 31, 

2014 

2013 

  $ 

  $ 

18,283     $ 
11,420       
29,703     $ 

28,533   
10,679   
39,212   

F- 15 

   
   
    
   
   
   
   
   
   
   
   
   
  
  
  
  
  
    
  
    
    
    
    
    
  
  
  
  
  
    
  
    
  
Note 4. Property and Equipment  

Property and equipment consist of the following:    

Cryogenic shippers 
Furniture and fixtures 
Machinery and equipment 
Leasehold improvements 

Less accumulated depreciation and amortization 

March  31, 

2014 
1,037,286     $ 
30,746       
386,731       
30,913       
1,485,676       
(1,076,784 )     
408,892     $ 

2013 

962,565   
30,746   
380,526   
30,913   
1,404,750   
(899,265 ) 
505,485   

  $ 

  $ 

Total depreciation and amortization expense related to property and equipment amounted to $219,400 and $281,700 for the years ended 

March 31, 2014 and 2013, respectively.  

Note 5. Intangible Assets  

Intangible assets consist of the following:  

Patents and trademarks 
Software development costs for internal use 

Total intangible assets 

March 31, 2014 

   Gross Amount     
  $ 

154,214     $ 
547,127       
701,341     $ 

  $ 

Accumulated 
Amortization      Net Amount      

(55,712 )   $ 
(465,543 )     
(521,255 )   $ 

98,502       
81,584       
180,086     

Weighted 
Average 
Amortization 
Period (years)   
4.9   
1.6   

Patents and trademarks 
Software development costs for internal use 

Total intangible assets 

  $ 

  $ 

154,214     $ 
547,127       
701,341     $ 

(54,251 )   $ 
(374,827 )     
(429,078 )   $ 

99,963       
172,300       
272,263       

March 31, 2013 

Gross  
Amount 

Accumulated  
Amortization     

Net  
Amount 

Weighted 
Average 
Amortization 
Period (years)   
5.9   
2.6   

Amortization expense for intangible assets for the years ended March 31, 2014 and 2013 was $92,200 and $112,300, respectively.  

Future amortization of intangible assets is as follows:  

Years Ending March 31, 
2015 
2016 
2017 
2018 
2019 

Note 6. Accrued Compensation and Related Expenses  

Accrued compensation and related expenses consist of the following:  

Accrued salary and wages 
Accrued paid time off 
Accrued board of director fees 
Other accrued obligations 

  $ 

62,884   
49,770   
28,199   
19,617   
19,616   
  $  180,086   

March 31, 

2014 

2013 

  $ 

  $ 

80,328     $ 
155,166       
214,553       
4,241       
454,288     $ 

85,554   
92,376   
38,000   
1,502   
217,432   

   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
    
  
    
    
    
  
    
    
  
  
  
    
  
  
  
    
    
  
  
    
  
  
  
  
    
    
    
    
    
  
    
    
    
    
  
  
  
  
  
  
    
  
    
    
    
  
F- 16 

Note 7. Related Party Transactions  

Related Party Notes Payable  

As of March 31, 2014 and 2013, the Company had aggregate principal balances of $555,500 and $651,500, respectively, in outstanding 

unsecured indebtedness owed to four related parties, including former members of the Company’s board of directors, representing working 
capital advances made to the Company from February 2001 through March 2005. These notes bear interest at the rate of 6% per annum and 
provide for aggregate monthly principal payments which began April 1, 2006 of $2,500, and which increased by an aggregate of $2,500 every 
nine months to a maximum of $10,000 per month. As of March 31, 2014, the aggregate principal payments totaled $8,000 per month. Any 
remaining unpaid principal and accrued interest is due at maturity on various dates through March 1, 2015.  

Related-party interest expense under these notes was $36,500 and $42,200 for the years ended March 31, 2014 and 2013, respectively. 

Accrued interest, which is included in related party notes payable in the accompanying consolidated balance sheets, amounted to $802,600 and 
$766,200 as of March 31, 2014 and 2013, respectively.  

Convertible Bridge Notes  

During the year ended March 31, 2014, the Company issued to certain accredited investors various unsecured promissory notes with the 

terms as described under Note 8. These unsecured promissory notes included $120,000 of the 5% Bridge Notes (as defined below) issued to 
Jerrell Shelton, the Company’s Chief Executive Officer, $100,000 of the Bridge Notes (as defined below) issued to Richard Rathmann, a 
member of the Board of Directors of the Company, $200,000 of the Bridge Notes and $100,000 of the 5% Bridge Notes issued to GBR 
Investments, LLC, of which Richard Rathmann is the manager.  

Note 8. Convertible Notes Payable  

2013 and 2014 Bridge Notes  

In the fourth quarter of fiscal 2013 and first nine months of fiscal 2014, the Company issued to certain accredited investors unsecured 

convertible promissory notes (the “Bridge Notes”) in the original principal amount of $1,294,500 and $2,765,301, respectively, for total 
principal of $4,059,801, pursuant to the terms of subscription agreements and letters of investment intent.  

The Bridge Notes accrued interest at a rate of 15% per annum from date of issuance until January 31, 2013 and at a rate of 5% per annum 
from February 1, 2013 through the date of payment, in each case on a non-compounding basis. All principal and interest under the Bridge Notes 
were due on December 31, 2013. Accrued interest related to these notes amounted to $0 and $9,900, as of March 31, 2014 and 2013, 
respectively.  

In connection with the issuance of the Bridge Notes to three accredited investors totaling $400,000 in June, July and August 2013, the 

Company granted these investors warrants to purchase 1,797,457 shares of common stock at an exercise prices ranging from $0.19 to $0.29 per 
share. The relative fair value of the warrants of $199,200 was recorded as a debt discount and was amortized to interest expense using the 
straight-line method which approximated the effective interest method over the term of the Bridge Notes. These Bridge Notes accrued interest at 
8% per annum from the date of issuance through date of payment, on a non-compounding basis. All other terms of these Bridge Notes are 
consistent with the rest of the Bridge Notes. Upon conversion of the Bridge Notes in September and October 2013, the remaining unamortized 
debt discount was amortized to interest expense.  

In September and October 2013, the Bridge Note holders accepted an offer by the Company and converted an aggregate of $4,127,202 of 
outstanding principal and accrued interest under the Bridge Notes into 20,636,011 units (the “Units”) at a price of $0.20 per Unit, with each Unit 
consisting of (i) one share of common stock of the Company (“Common Stock”) and (ii) one warrant to purchase one share of Common Stock at 
an exercise price of $0.37 per share. The warrants are exercisable beginning on March 31, 2014 and have a term of five years from date of 
issuance. As the transaction was considered an induced conversion under the applicable accounting guidance, the Company recognized 
$13,713,767 in debt conversion expense representing the fair value of the securities transferred in excess of the fair value of the securities 
issuable upon the original conversion terms of the Bridge Notes. The Company calculated the fair value of the common stock issued by using the 
closing price of the stock on the date of issuance. The fair value of the warrants was calculated using Black-Scholes.  

F- 17 

   
   
   
   
   
   
   
   
   
   
   
   
   
  
Upon conversion of the Bridge Notes, the remaining unamortized debt discount was amortized to interest expense. During the years ended 

March 31, 2014 and 2013, the Company amortized $199,200 and $0, respectively, to interest expense.  

5% Bridge Notes  

From December 2013 to March 2014, the Company issued to certain accredited investors unsecured convertible promissory notes (the 

“5% Bridge Notes”) in the original principal amount of $1,793,000, pursuant to the terms of subscription agreements and letters of investment 
intent. This includes two notes in the aggregate amount of $120,000 issued to Jerrell Shelton, the Company’s Chief Executive Officer, on 
December 11, 2013 and January 10, 2014 as well as a note in the amount of $100,000 issued to GBR Investments, LLC on February 3, 2014, of 
which Richard Rathmann, a Director of the Company, is the manager.  

The 5% Bridge Notes accrue interest at a rate of 5% per annum from the date of issuance through date of payment, on a non-compounding 

basis. All principal and interest under the 5% Bridge Notes becomes due on June 30, 2014. Accrued interest related to these notes of $14,100 is 
included in convertible debentures payable and accrued interest, net of discount in the accompanying consolidated balance sheet at March 31, 
2014.  

In connection with the issuance of the 5% Bridge Notes, the Company granted these investors warrants to purchase 896,500 shares of 
common stock at an exercise price of $0.49 per share. The warrants are exercisable on May 31, 2014 and expire on December 31, 2018. The 
relative fair value of the warrants of $279,100 was recorded as a debt discount and is amortized to interest expense using the straight-line method 
which approximates the effective interest method over the term of the 5% Bridge Notes.  During the year ended March 31, 2014, the Company 
amortized $94,300 of the debt discount to interest expense for these notes.  

In the event the Company designates and issues one or more types of equity securities while the 5% Bridge Notes are outstanding 

(“Subsequent Offering”), the Company must provide written notice to the holders of the notes and such holders will have a right to convert up to 
all of the principal and accrued unpaid interest on the notes into shares of such equity securities on the same terms as the Subsequent Offering 
during the ten days following the provision of such notice. The conversion price for these equity securities will be 90% of the offering price for 
the equity securities. The Company was unable to value the conversion feature of these 5% Bridge Notes given the absence of a conversion rate 
and the convertibility of the 5% Bridge Notes being contingent upon the completion of a Subsequent Offering. In May 2014, note holders with 
the principal amount of $1,743,000 converted their notes (see Note 15).  

Emergent Financial Group, Inc. (“Emergent”) served as the Company’s placement agent in connection with the original placement of the 

Bridge Notes and 5% Bridge Notes and earned a commission of 9% of the original principal balance of such notes. Debt financing costs of 
$375,900 and $116,500 in 2014 and 2013, respectively, comprised primarily of the commission earned by Emergent, of which $98,400 and 
$107,800 is recorded in other current assets in the accompanying consolidated balance sheets as of March 31, 2014 and 2013, respectively, and 
are being amortized to interest expense using the straight-line method which approximates the effective interest method over the term of the 
notes.  

In connection with the conversion of the Bridge Notes in September and October 2013, Emergent received warrants to purchase 1,911,259 
shares of common stock at an exercise price of $0.20 per share. The warrants were exercisable beginning March 31, 2014 and have an expiration 
date of June 30, 2018. Emergent did not receive any compensation with respect to the 5% Bridge Note in the principal amount of $120,000 
issued to Jerrell Shelton, the Chief Executive Officer of the Company and $100,000 issued to GBR Investments, LLC , of which Richard 
Rathmann, a Director of the Company, is the manager. During the years ended March 31, 2014 and 2013, the Company amortized $385,400 and 
$8,700, respectively, to interest expense.  

Note 9. Derivative Liabilities  

In accordance with applicable accounting guidance, certain of the Company’s outstanding warrants to purchase shares of common stock 

were treated as derivatives because these instruments had reset or ratchet provisions in the event the Company raises additional capital at a lower 
price, among other adjustments. As such, the fair value of these common stock purchase warrants were treated as derivative liabilities since their 
date of issuance or modification. Changes in fair value were recorded as non-operating, non-cash income or expense at each reporting date. If the 
fair value of the derivatives is higher at the subsequent balance sheet date, the Company will record a non-operating, non-cash charge. If the fair 
value of the derivatives is lower at the subsequent balance sheet date, the Company will record non-operating, non-cash income. As of March 31, 
2014 and 2013, the Company had derivative warrant liabilities with fair values of $0 and $20,848, respectively. The derivative warrants expire in 
April 2014.  

F- 18 

   
   
   
   
   
   
   
   
   
   
   
  
During the year ended March 31, 2014 and 2013, the Company recognized aggregate gains of $20,848 and $16,486, respectively, due to 

the change in fair value of its derivative instruments.  

The Company’s common stock purchase warrants do not trade in an active securities market, and as such, the Company estimated the fair 

value of these warrants using Black-Scholes using the following assumptions:  

Expected life (years) 

Risk-free interest rate 

Volatility 
Dividend yield 

March 31, 

2014 

2013 

     0.01 to 0.81        1.01 to 1.81   

0.03% -
 0.15%       

     70% - 144%       
—      

0.14%-
0.33%   
129% -

158%   
—  

Historical volatility was computed using daily pricing observations for recent periods that correspond to the remaining term of the 
warrants, which had an original term of five years from the date of issuance. The expected life is based on the remaining term of the warrants. 
The risk-free interest rate is based on U.S. Treasury securities with a maturity corresponding to the remaining term of the warrants.  

Note 10. Commitments and Contingencies  

Facility and Equipment Leases  

We  lease  11,900  square  feet  of  corporate,  research  and  development,  and  warehouse  facilities  in  Lake  Forest,  California  under  an 
operating lease expiring June 30, 2015 which includes the right to cancel the lease with a minimum of 120 day written notice at any time after 
December 31, 2012. We also lease corporate facilities in San Diego, California under a non-cancelable operating lease expiring December 31, 
2014. Each lease agreement contains certain scheduled rent increases which are accounted for on a straight-line basis.  

Future minimum lease payments are as follows:  

Years ending March 31, 
2015 
2016 

   Operating Leases   
192,800   
  $ 
26,700   
219,500   

  $ 

Rent expense for the years ended March 31, 2014 and 2013 was approximately $178,000 and $204,000, respectively.  

Employment Agreements  

We have entered into employment agreements with certain of our officers under which payment and benefits would become payable in the 
event of termination by us for any reason other than cause, or upon a change in control of our Company, or by the employee for good reason.  

Consulting and Engineering Services  

Effective November 1, 2010, the Company entered into a Second Amendment to Master Consulting and Engineering Services Agreement 

(the “Second Amendment”) with KLATU Networks, LLC (“KLATU”), which amended the Master Consulting and Engineering Services 
Agreement between the parties dated as of October 9, 2007 (the “Agreement”), as amended by the First Amendment to Master Consulting and 
Engineering Services Agreement between the parties dated as of April 23, 2009. The parties entered into the Second Amendment to clarify their 
mutual intent and understanding that all license rights granted to the Company under the Agreement, as amended, shall survive any termination 
or expiration of the Agreement. In addition, in recognition that the Company has paid KLATU less than the market rate for comparable services, 
the Second Amendment provides that if the Company terminates the Agreement without cause, which the Company has no intention of doing, or 
liquidates, KLATU shall be entitled to receive additional consideration for its services provided from the commencement of the Agreement 
through such date of termination, which additional compensation shall not be less than $2 million plus two times the “cost of work” (as defined 
in the Agreement). Any such additional compensation would be payable in three equal installments within 12 months following the date the 
amount of such additional compensation is determined. If KLATU terminates that agreement, no such payments are payable.  

F- 19 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
    
  
  
  
      
  
    
    
    
  
The agreement provides for one year terms ending on December 31 of each year, but it automatically renews for one year periods unless 
otherwise terminated. Consulting fees for services provided by KLATU were $395,300 and $401,100 for the years ended March 31, 2014 and 
2013, respectively.  

Litigation  

The Company may become a party to product litigation in the normal course of business. The Company accrues for open claims based on 
its historical experience and available insurance coverage. In the opinion of management, there are no legal matters involving the Company that 
would have a material adverse effect upon the Company’s consolidated financial condition or results of operations.  

Indemnities and Guarantees  

The Company has made certain indemnities and guarantees, under which it may be required to make payments to a guaranteed or 
indemnified party, in relation to certain actions or transactions. The guarantees and indemnities do not provide for any limitation of the 
maximum potential future payments the Company could be obligated to make. Historically, the Company has not been obligated nor incurred 
any payments for these obligations and, therefore, no liabilities have been recorded for these indemnities and guarantees in the accompanying 
consolidated balance sheets.  

The Company indemnifies its directors, officers, employees and agents, as permitted under the laws of the States of California and 
Nevada. In connection with its facility leases, the Company has indemnified its lessors for certain claims arising from the use of the facilities. 
The duration of the guarantees and indemnities varies, and is generally tied to the life of the agreement.  

Note 11. Stockholders’ Equity  

Authorized Stock  

The  Company  has  250,000,000  authorized  shares  of  common  stock  with  a  par  value  of  $0.001  per  share.  In  September  2011,  our 
stockholders  approved  an  amendment  to  the  Amended  and  Restated  Articles  of  Incorporation  to  authorize  a  class  of  undesignated  or  "blank 
check" preferred stock, consisting of 2,500,000 shares at $0.001 par value per share. Shares of preferred stock may be issued in one or more 
series, with such rights, preferences, privileges and restrictions to be fixed by the Company's board of directors. In May 2014, our stockholders 
approved a Certificate of Designation, which designated 800,000 shares of preferred stock as Class A Preferred Stock (See Note 15).  

Common Stock Reserved for Future Issuance  

As of March 31, 2014, approximately 73.1 million shares of common stock were issuable upon conversion or exercise of rights granted 

under prior financing arrangements, stock options and warrants, as follows:  

Exercise of stock options 
Exercise of warrants  
Total shares of common stock reserved for future issuances 

Note 12. Stock-Based Compensation  

Warrant Activity  

11,894,205   
61,194,343   
73,088,548   

We typically issue warrants to purchase shares of our common stock to investors as part of a financing transaction or in connection with 
services rendered by placement agents and consultants. Included in outstanding warrants are 262,856 and 312,856 warrants at March 31, 2014 
and 2013, respectively issued to employees or directors. Our outstanding warrants expire on varying dates through July 2019. A summary of 
warrant activity is as follows:  

F- 20 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
    
    
  
Outstanding — March 31, 2012 

Issued 
Exercised 
Forfeited 
Expired 

Outstanding — March 31, 2013 

Issued 
Exercised 
Forfeited 
Expired 

Outstanding — March 31, 2014 
Vested (exercisable) — March 31, 2014 

Weighted-  
Average  
Exercise  

Number of  
Shares 
37,144,504      $ 
30,000     
—    
(123,376 )   
(23,929 )   
37,027,199     
25,241,227     
(926,315 )   
(39,728 )   
(108,040 )   
61,194,343      $ 
60,297,010      $ 

Price/Share      
1.18     
0.50     
—    
0.77     
8.89     
1.18     
0.35     
0.22     
8.49     
7.96     
0.84     
0.84     

Weighted-  
Average  
Remaining  
Contractual  
Term (Years)     

Aggregate  
Intrinsic  
Value (1) 

2.9      $ 
2.9      $ 

3,987,500   
3,960,600   

(1)  Aggregate intrinsic value represents the difference between the exercise price of the warrant and the closing market price of the common 

stock on March 31, 2014, which was $0.52 per share. 

The following table summarizes information with respect to warrants outstanding and exercisable at March 31, 2014:  

Exercise Price  
$0.19 – 0.20 
$0.21 – 0.37 
$0.38 – 0.69 
$0.70 – 0.92 
$0.93 – 10.80 

Number  
Outstanding     
     2,437,574       
     20,980,838       
     10,932,429       
     21,431,557       
     5,411,945       
     61,194,343       

Stock Options  

Weighted-  
Average  
Remaining  
Contractual 

Life (Years)       
4.3     $ 
4.5     $ 
3.0     $ 
1.7     $ 
0.9     $ 

Weighted-  
Average  
Exercise Price     
0.20       
0.37       
0.67       
0.77       
3.53       

Weighted-  
Average  
Exercise Price   
0.20   
0.37   
0.69   
0.77   
3.53   

Number  

Exercisable       
2,437,574     $ 
20,980,838     $ 
10,035,929     $ 
21,431,557     $ 
5,411,112     $ 
60,297,010       

We have three stock incentive plans: the 2002 Stock Incentive Plan, or the 2002 Plan, the 2009 Stock Incentive Plan, or the 2009 Plan and 
the 2011 Stock Incentive Plan, or the 2011 Plan (collectively, the “Plans”). The 2002 Plan authorizes the grant of incentive awards, including 
stock options, for the purchase of up to a total of 500,000 shares and has no shares available for future issuances as the 2002 Plan has expired. 
Subsequent to the adoption of the 2011 Plan, no new options have been granted pursuant the 2009 Plan or 2002 Plan. In September 2009, the 
stockholders approved the issuance of up to 1,200,000 shares of common stock available for issuance under the 2009 Plan and as of March 31, 
2014, the  Company  has 299,741  shares  available for future  awards  under the  2009 Plan.  In  September 2011,  the  stockholders  authorized  the 
issuance  of  up  to  2,300,000  shares  of  the  Company's  common  stock.  On  September 13,  2012,  the  stockholders  approved  an  increase  to  the 
number of shares of the Company’s common stock available for issuance by 3,000,000 shares. On September 6, 2013 the stockholders approved 
an increase to the number of shares of the Company’s common stock available for issuance by 7,100,000 shares. As of March 31, 2014, there 
were 7,405,004 incentive awards available for grant under the 2011 Plan.  

During each of the two years in the period ended March 31, 2014, we granted stock options at exercise prices equal to or greater than the 
quoted market price of our common stock on the grant date. The fair value of each option grant was estimated on the date of grant using the 
Black-Scholes option pricing model with the following weighted average assumptions:  

Expected life (years) 

Risk-free interest rate 
Volatility 
Dividend yield 

March 31, 

2014  
1.6 – 6.02      
0.19% -
 1.84%      
   127% - 140%      
0 %   

2013  

2.6 -10.0   

   0.63%-2.22%   
   124% - 166%   

0 % 

   
   
   
   
   
   
   
   
   
  
  
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
  
  
  
 
  
        
        
    
     
  
  
  
     
  
  
  
  
  
  
  
  
  
  
  
The expected option life assumption is estimated based on the simplified method. Accordingly, the Company has utilized the average of 
the contractual term of the options and the weighted average vesting period for all options to calculate the expected option term. The risk-free 
interest rate  assumption is based upon observed interest rates appropriate for the expected term of  our employee stock options.  The expected 
volatility is based on the historical volatility of our stock commensurate with the expected life of the stock-based award. We do not anticipate 
paying dividends on the common stock in the foreseeable future.  

We  recognize  stock-based  compensation  cost  over  the  vesting  period  using  the  straight-line  single  option  method.  Stock-based 
compensation expense is recognized only for those awards that are ultimately expected to vest. An estimated forfeiture rate has been applied to 
unvested  awards  for  the  purpose  of  calculating  compensation  cost.  The  estimated  forfeiture  rate  of  0%  per  year  is  based  on  the  historical 
forfeiture  activity  of  unvested  stock  options.  These  estimates  are  revised,  if  necessary,  in  future  periods  if  actual  forfeitures  differ  from  the 
estimates. Changes in forfeiture estimates impact compensation cost in the period in which the change in estimate occurs.  

A summary of stock option activity is as follows:    

Outstanding — March 31, 2012 

Granted (weighted-average fair value of $0.26 per share) 
Exercised 
Forfeited 
Expired 

Outstanding — March 31, 2013 

Granted (weighted-average fair value of $0.24 per share) 
Exercised 
Forfeited 
Expired 

Outstanding — March 31, 2014 
Vested (exercisable) — March 31, 2014 
Unvested (unexercisable) — March 31, 2014 

Number of  
Shares 

1,355,132      $ 
4,063,109     
—    
(322,500 )   
—    

5,095,741      $ 
7,673,272     
(657,000 )   
(197,808 )   
(20,000 )   
11,894,205      $ 
5,543,002      $ 
6,351,203      $ 

Weighted-  
Average  
Exercise  

Price/Share      
1.14     
0.29     
—    
0.98     
—    
0.47     
0.28     
0.20     
0.32     
6.00     
0.35     
0.42     
0.30     

Weighted-  
Average  
Remaining  
Contractual  
Term (Years)     

Aggregate  
Intrinsic  
Value (1) 

8.6      $ 
8.0      $ 
3.0      $ 

2,578,900   
1,110,600   
1,468,300   

(1)  Aggregate intrinsic value represents the difference between the exercise price of the option and the closing market price of the common 

stock on March 31, 2014, which was $0.52 per share. 

The following table summarizes information with respect to stock options outstanding and exercisable at March 31, 2014:  

Exercise Price  
$0.17 – 0.48 
$0.52 – 0.98 
$1.05 – 2.20 
$4.30 – 8.31 

Weighted-  
Average  
Remaining  
Contractual 
Life (Years)     

Weighted-  
Average  
Exercise  
Price  

Number  
Outstanding  

10,523,036        
1,234,469        
48,600        
88,100        

11,894,205     

8.9      $ 
6.3      $ 
6.4      $ 
2.3      $ 

0.27        
0.66        
1.64        
4.74        

Number  

Exercisable       

Weighted-  
Average  
Exercise  
Price  

4,428,083      $ 
987,594      $ 
39,225      $ 
88,100      $ 

5,543,002     

0.27   
0.66   
1.69   
4.74   

As of March 31, 2014, there was unrecognized compensation expense of $1.6 million related to unvested stock options, which we expect 

to recognize over a weighted average period of 3.0 years.  

F- 21 

   
   
   
   
   
   
   
   
     
  
  
  
  
    
  
    
  
    
  
  
  
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
      
  
    
  
  
  
  
  
  
  
  
  
  
    
    
  
     
     
     
     
  
  
      
      
    
Note 13. Income Taxes  

Significant components of the Company’s deferred tax assets as of March 31, 2014 and 2013 are shown below:  

Deferred tax assets: 
Net operating loss carryforward 
Research credits 
Expenses recognized for granting of options and warrants 
Accrued expenses and reserves 
Valuation allowance 

March 31,  

2014  

2013  

   $ 

   $ 

(000’s) 
15,379      $ 
60     
1,651     
135     
(17,225 )   

—     $ 

13,505   
51   
1,319   
32   
(14,907 ) 
—  

Based on the weight of available evidence, the Company’s management has determined that it is more likely than not that the net deferred 

tax assets will not be realized. Therefore, the Company has recorded a full valuation allowance against the net deferred tax assets. The 
Company’s income tax provision consists of state minimum taxes.  

The income tax provision differs from that computed using the federal statutory rate applied to income before taxes as follows:  

Computed tax benefit at federal statutory rate 
State tax, net of federal benefit 
Warrant MTM Adjustment 
Induced conversion costs 
Interest expense 
Permanent items and other 
Valuation allowance 

March 31,  

2014  

2013  

(327,000 )      
(7,000 )      
      4,663,000        
—       
4,600        

   $  (6,650,000 )    $  (2,169,000 ) 
(359,000 ) 
(6,000 ) 
—  
1,000   
215,600   
      2,318,000         2,319,000   
1,600   
1,600      $ 
   $ 

At March 31, 2014, the Company has federal and state net operating loss carryforwards of approximately $39,086,000 and $35,759,000 

which will begin to expire in 2020, unless previously utilized, and as of 2012 have already begun to for state carryforwards. At March 31, 2014, 
the Company has federal and California research and development tax credits of approximately $18,000 and $64,000, respectively. The federal 
research tax credit begins to expire in 2026 unless previously utilized and the California research tax credit has no expiration date.  

 Utilization of the net operating loss and research and development carryforwards might be subject to a substantial annual limitation due to 
ownership change limitations that may have occurred or that could occur in the future, as required by Section 382 of the Internal Revenue Code 
of 1986, as amended (the “Code”), as well as similar state and foreign provisions. These ownership changes may limit the amount of NOL and 
R&D credit carryforwards that can be utilized annually to offset future taxable income and tax, respectively. In general, an “ownership change” 
as defined by Section 382 of the Code results from a transaction or series of transactions over a three-year period resulting in an ownership 
change of more than 50 percentage points of the outstanding stock of a company by certain stockholders or public groups. Since the Company’s 
formation, the Company has raised capital through the issuance of capital stock on several occasions which, combined with the purchasing 
stockholders’ subsequent disposition of those shares, may have resulted in such an ownership change, or could result in an ownership change in 
the future upon subsequent disposition.    

The Company has not completed a study to assess whether an ownership change has occurred. If the Company has experienced an 
ownership change, utilization of the NOL or R&D credit carryforwards would be subject to an annual limitation under Section 382 of the Code, 
which is determined by first multiplying the value of the Company’s stock at the time of the ownership change by the applicable long-term, tax-
exempt rate, and then could be subject to additional adjustments, as required. Any limitation may result in expiration of a portion of the NOL or 
R&D credit carryforwards before utilization. Further, until a study is completed and any limitation is known, no amounts are being considered as 
an uncertain tax position or disclosed as an unrecognized tax benefit. Due to the existence of the valuation allowance, future changes in the 
Company’s unrecognized tax benefits will not impact its effective tax rate. Any carryforwards that will expire prior to utilization as a result of 
such limitations will be removed from deferred tax assets with a corresponding reduction of the valuation allowance.   

On September 13, 2013, the U.S. Treasury Department released final income tax regulations on the deduction and capitalization of 
expenditures related to tangible property. These final regulations apply to tax years beginning on or after January 1, 2014, and may be adopted in 
earlier years. The Company does not intend to early adopt the tax treatment of expenditures to improve tangible property and the capitalization 
of inherently facilitative costs to acquire tangible property as of January 1, 2013. The tangible property regulations will require the Company to 
make additional tax accounting method changes as of January 1, 2014; however, management does not anticipate the impact of these changes to 
be material to the Company’s consolidated financial position, its results of operations and its footnote disclosures.  

   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
    
  
     
     
     
     
  
F- 22 

Note 14. Quarterly Financial Data (Unaudited)  

A summary of quarterly financial data is as follows ($ in ‘000’s):  

Year ended March 31, 2014 
Total revenues 
Gross margin 
Operating loss 
Net loss 
Net loss per share, basic and diluted 

Year ended March 31, 2013 
Total revenues 
Gross loss 
Operating loss 
Net loss 
Net loss per share, basic and diluted 

June 30  

September 30      

December 
31  

     March 31     

Quarter Ended  

   $ 
   $ 
   $ 
   $ 
   $ 

   $ 
   $ 
   $ 
   $ 
   $ 

488      $ 
55      $ 
(1,260 )    $ 
(1,324 )    $ 
(0.03 )    $ 

191      $ 
(163 )    $ 
(1,541 )    $ 
(1,546 )    $ 
(0.04 )    $ 

580      $ 
72      $ 
(1,287 )    $ 
(14,960 )    $ 
(0.38 )    $ 

234      $ 
(111 )    $ 
(1,554 )    $ 
(1,551 )    $ 
(0.04 )    $ 

757      $ 
167      $ 
(1,257 )    $ 
(1,840 )    $ 
(0.03 )    $ 

307      $ 
(62 )    $ 
(1,549 )    $ 
(1,567 )    $ 
(0.04 )    $ 

835   
143   
(1,274 ) 
(1,441 ) 
(0.02 ) 

368   
(153 ) 
(1,681 ) 
(1,717 ) 
(0.05 ) 

Earnings  per basic and diluted  shares are  computed independently  for  each of  the  quarters presented based  on  basic  and  diluted  shares 

outstanding per quarter and, therefore, may not sum to the totals for the year.  

Note 15. Subsequent Events  

Designation of Class A Preferred Stock  

On May 2, 2014, the Company filed with the Secretary of State of the State of Nevada a Certificate of Designation which designated 

800,000 shares of the Company’s previously authorized preferred stock, par value $0.001, as Class A Preferred Stock (“Preferred Stock”).  

The rights, preferences, and privileges of the Preferred Stock are summarized as follows: 

•  Dividends shall accrue on shares of Preferred Stock at the rate of $0.96 per annum. Such dividends shall accrue day-to-day, shall be 

cumulative, and shall be payable on when, as, and if declared by the Board of Directors of the Company. 

• 

In the event of any voluntary or involuntary liquidation, dissolution, or winding up of the Registrant, holders of Preferred Stock then 
outstanding shall be entitled to receive a preference payment equal to $12.00 per share (subject to appropriate adjustment in the event of 
a stock dividend, split, combination, or other similar recapitalization) plus any accrued dividends, but unpaid thereon, whether or not 
declared, together with any other dividends declared but unpaid thereon. 

•  Shares of Preferred Stock shall vote together with the common stock on an as-converted basis. 

•  At any time after September 1, 2014, shares of Preferred Stock shall be convertible into thirty shares of Common Stock. In addition, 
accrued but unpaid dividends on the Preferred Stock will also be convertible into common stock after September 1, 2014 at the rate of 
one share for each $0.40 of dividend. Such conversion is subject to adjustment in the event of any stock split or combination, certain 
dividends and distributions, and any reorganization, recapitalization, reclassification, consolidation, or merger involving the Company. 

•  Shares of the Preferred Stock shall be subject to redemption by the Company at any time on or after January 15, 2017, upon payment of 
$12.00 per share (subject to appropriate adjustment in the event of a stock dividend, split, combination, or other similar recapitalization) 
plus all accrued but unpaid dividends thereon. 

•  The  Preferred  Stock  is  subject  to  a  liquidation  preference  over  common  stock  equal  to  $12  per  share  and  the  unpaid  accrued 
dividend.  Holders of the Preferred Stock will vote with holders of the Company’s common stock, but will have thirty votes per share of 
Preferred Stock held compared to one vote for each share of common stock.   

F- 23 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
    
  
  
    
  
    
  
    
  
  
  
  
  
      
  
      
  
      
  
    
  
  
      
  
      
  
      
  
    
  
  
  
  
  
  
  
  
  
Issuance of Class A Preferred Stock  

In  May  2014,  the  Company  entered  into  definitive  agreements  for  a  private  placement  of  its  securities  to  certain  institutional  and 
accredited  investors  (the  “Investors”)  pursuant  to  certain  Subscription  Agreements  and  Elections  to  Convert  between  the  Company  and  the 
Investors. Through June 13, 2014, aggregate gross cash proceeds of $839,600 (approximately $628,700 after estimated cash offering expenses) 
were collected in exchange for the issuance of 69,964 shares of our Class A Preferred Stock, and warrants, exercisable for five years, to purchase 
up to a total of 559,712 shares of our common stock at an exercise price of $0.50 per share. The Company intends to use the net proceeds for 
working capital purposes.  

Pursuant to the Subscription Agreements, the Company issued shares of a newly established Class A Preferred Stock and warrants to 
purchase common stock of Cryoport. The shares and warrants were issued as a unit (a “Unit”) consisting of (i) one share of Class A Convertible 
Preferred  Stock  and  (ii) one  warrant  to  purchase  eight  (8)  shares  of  Common  Stock  at  an  exercise  price  of  $0.50  per  share,  which  are 
immediately exercisable and may be exercised at any time on or before March 31, 2019.  

Pursuant  to  the  terms  of  the  5%  Bridge  Notes  issued  by  the  Company  between  December  6,  2013  and  March  13,  2014  with  a  total 
original principal amount of $1,793,000 (the “5% Bridge Notes”), the issuance of the Units to Investors at $12.00 per Unit entitled the holders of 
the 5% Bridge Notes to convert up to the entire principal amount and accrued interest under the 5% Bridge Notes into Units at a rate of $10.80 
per  Unit.  Through  June  13,  2014,  5%  Bridge  Note  holders  totaling  $1,743,000  in  original  principal  sum  elected  to  convert  their  5%  Bridge 
Notes,  including  accrued  interest,  for  Units  in  exchange  for  the  issuance  of  163,608  shares  of  our  Class  A  Preferred  Stock  and  warrants  to 
purchase up to 1,308,864 shares of our commons stock at an exercise price of $0.50 per share. Two of the 5% Bridge Note holders that executed 
Subscription Agreements to convert 5% Bridge Notes in the aggregate principal amount of $220,000, are affiliates of the Company – Jerrell W. 
Shelton,  the  Company’s  Chief  Executive  Officer,  and  GBR  Investments,  LLC,  which  is  managed  by  Richard  Rathmann,  a  Director  and 
Chairman of the Board of Directors of the Company (collectively, the “Affiliates”).  

Emergent Financial  Group,  Inc. served as  the Company’s placement agent in this  transaction  and received,  with respect to the gross 
proceeds  received  from  Investors  who  converted  their  5%  Bridge  Notes  into  Units  (not  including  those  conversions  by  the  Affiliates),  a 
commission  of  3%  and  a  non-accountable  finance  fee  of  1%  of  such  proceeds,  and  with  respect  to  gross  proceeds  received  from  all  other 
Investors, a commission of 10% and a non-accountable finance fee of 3% of the aggregate gross proceeds received from such Investors, plus 
reimbursement  of  legal  expenses  of  up  to  $40,000.  Emergent  Financial  Group,  Inc.  will  also  be  issued  a  warrant  to  purchase  three  shares  of 
Common Stock at an exercise price of $0.50 per share for each Unit issued in this transaction. The Company and Emergent Financial Group, Inc. 
have agreed that the offering of Units to new Investors will conclude on July 14, 2014.  

As of June 13, 2014, 233,572 shares of Preferred Stock and 1,868,576 of the related warrants were outstanding for Investors and 638,646 

warrants were outstanding for Emergent in connection with the Preferred Stock offering and the 5% Bridge Notes conversion.  

F- 24 

   
   
   
   
   
   
   
  
Exhibit 
No.  

Index to Exhibits  

Description  

3.1 

3.2 

3.3 

  Amended and Restated Articles of Incorporation of the Company, as amended.  Incorporated by reference to Exhibit 3.1 to the 
Company’s Quarterly Report on Form 10-Q for the Quarter Ended September 30, 2012. 

  Amended and Restated Bylaws of the Company.  Incorporated by reference to Exhibit 3.2 of the Company’s Current Report on Form 8-
K dated October 23, 2012. 

  Cryoport Systems, Inc. 2002 Stock Incentive Plan adopted by the Board of Directors on October 1, 2002.  Incorporated by reference to 
Exhibit 3.13 to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

3.4 

  Certificate of Designation.  Incorporated by reference to Exhibit 3.1 of the Company’s Current Report on Form 8-K dated May 2, 2014. 

4.1.1 

  Form of Debenture—Original Issue Discount 8% Secured Convertible Debenture dated September 28, 2007. Incorporated by reference 
to Cryoport’s Registration Statement on Form SB-2 dated November 9, 2007. 

4.1.2 

  Amendment to Convertible Debenture dated February 19, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K 
dated March 7, 2008 and referred to as Exhibit 10.1.10. 

4.1.3 

  Amendment to Convertible Debenture dated April 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 
April 30, 2008 and referred to as Exhibit 10.1.11. 

4.1.4 

  Annex to Amendment to Convertible Debenture dated April 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 
8-K dated April 30, 2008 and referred to as Exhibit 10.1.11.1. 

4.1.5 

  Amendment to Convertible Debenture dated August 29, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K 
dated August 29, 2008. 

4.1.6 

  Amendment to Convertible Debenture effective January 27, 2009 and dated February 20, 2009. Incorporated by reference to Cryoport’s 
Current Report on Form 8-K dated February 19, 2009. 

4.1.7 

4.1.8 

4.1.9 

  Amendment to Debentures and Warrants with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified Strategy 
Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated September 1, 2009. Incorporated by reference to 
Cryoport’s Current Report on Form 8-K dated September 17, 2009. 

  Amendment to Debentures and Warrants, Agreement and Waiver with Enable Growth Partners LP, Enable Opportunity Partners LP, 
Pierce Diversified Strategy Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated January 12, 2010. 
Incorporated by reference to Cryoport’s Current Report on Form 8-K dated January 15, 2010. 

  Amendment Agreement with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified Strategy Master Fund 
LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated February 1, 2010. Incorporated by reference to Cryoport’s Current 
Report on Form 8-K dated February 3, 2010. 

4.1.10    Amended and Restated Amendment Agreements with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified 

Strategy Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated  
February 19, 2010. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated February 26, 2010. 

4.1.11    First Amendment to Amended and Restated Amendment Agreements with Enable Growth Partners LP, Enable Opportunity Partners 
LP, Pierce Diversified Strategy Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. dated February 23, 2010. 
Incorporated by reference to Cryoport’s Current Report on Form 8-K dated February 26, 2010.  

4.2 

  Form of Common Stock Purchase Warrant dated September 28, 2007. Incorporated by reference to Cryoport’s Registration Statement 
on Form SB-2 dated November 9, 2007. 

   
   
   
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
   
  
Exhibit 
No.  

Description  

4.3 

4.4 

4.5 

4.6 

4.7 

4.8 

4.9 

4.10 

4.11 

4.12 

4.13 

4.14 

4.15 

4.16 

4.17 

  Original Issue Discount 8% Secured Convertible Debenture dated May 30, 2008. Incorporated by reference to Cryoport’s Current 
Report on Form 8-K dated June 9, 2008. 

  Common Stock Purchase Warrant dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 
9, 2008 . 

  Common Stock Purchase Warrant dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 
9, 2008 . 

  Form of Warrant and Warrant Certificate in connection with the February 25, 2010 public offering. Incorporated by reference to 
Cryoport’s Amendment No. 5 to Form S-1/A Registration Statement dated February 9, 2010. 

  Form of Securities Purchase Agreement in connection with the August to October 2010 private placement. Incorporated by reference to 
Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Form of First Amendment to Security Purchase Agreement in connection with the August to October 2010 private placement. 
Incorporated by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Form of Securities Purchase Agreement (Continuation of the Placement) in connection with the August to October 2010 private 
placement. Incorporated by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Registration Rights Agreement in connection with the August to October 2010 private placement. Incorporated by reference to 
Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Form of Joinder to Registration Rights Agreement in connection with the August to October 2010 private placement. Incorporated by 
reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

  Form of Securities Purchase Agreement in connection with the February 2011 private placement. Incorporated by reference to 
Cryoport’s Registration Statement on Form S-1 dated April 1, 2011. 

  Form of Registration Rights Agreement in connection with the February 2011 private placement. Incorporated by reference to 
Cryoport’s Registration Statement on Form S-1 dated April 1, 2011. 

  Form of Warrant in connection with the August to October 2010 private placement. Incorporated by reference to Cryoport’s 
Registration Statement on Form S-1/A dated April 22, 2011. 

  Form of Warrant in connection with the February 2011 private placement. Incorporated by reference to Cryoport’s Registration 
Statement on Form S-1/A dated April 22, 2011. 

  Form of Securities Purchase Agreement. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC on 
February 24, 2012. 

  Form of Registration Rights Agreement. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC on 
February 24, 2012. 

4.18 

  Form of Warrant. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC on February 24, 2012. 

4.19 

  Warrant issued to Rodman & Renshaw, LLC in connection with the February 25, 2010 public offering. Incorporated by reference to 
CryoPort’s Registration Statement on Form S-1 dated October 19, 2010. 

4.20 

4.21 

Form of Warrant issued with Convertible Promissory Notes.  Incorporated by reference to Exhibit 4.20 of Cryoport’s Quarterly Report 
on Form 10-Q for the Quarter Ended September 30, 2013. 

Form of Warrant issued upon Conversion of Convertible Promissory Notes.  Incorporated by reference to Exhibit 4.21 of Cryoport’s 
Quarterly Report on Form 10-Q for the Quarter Ended September 30, 2013. 

   
   
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
  
    
  
  
Exhibit 
No.  

4.22 

4.23 

Description  

Form of Warrant Issued to Placement Agents.  Incorporated by reference to Exhibit 4.22 of Cryoport’s Quarterly Report on Form 10-Q 
for the Quarter Ended September 30, 2013. 

Form of Warrant issued with Convertible Promissory Notes (5% Bridge Notes).  Incorporated by reference to Exhibit 4.23 of Cryoport’s 
Quarterly Report on Form 10-Q for the Quarter Ended December 31, 2013. 

4.24+ 

  Form of Warrant issued in connection with the May 2014 private placement. 

10.1.1    Commercial Promissory Note between Cryoport, Inc. and D. Petreccia executed on August 26, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.2    Commercial Promissory Note between Cryoport, Inc. and J. Dell executed on September 1, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.3    Commercial Promissory Note between Cryoport, Inc. and P. Mullens executed on September 2, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.4    

Commercial Promissory Note between Cryoport, Inc. and R. Takahashi executed on August 25, 2005. Incorporated by reference to 
Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.5.2    

Second Amendment To Lease: Renewal dated August 24, 2009, between CryoPort, Inc. and Viking Inventors-Barents Sea LLC. 
Incorporated by reference to Cryoport’s Amendment No. 1 to Form S-1/A Registration Statement dated January 12, 2010. 

10.5.3    

Third Amendment to Lease: Renewal dated June 8, 2010 between Viking Investors Barents Sea, LLC. Incorporated by reference to 
Exhibit 10.5.3 to Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2013. 

10.6 

10.7 

10.9 

Securities Purchase Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form SB-
2 dated November 9, 2007 and referred to as Exhibit 10.6. 

  Registration Rights Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form SB-
2 dated November 9, 2007 and referred to as Exhibit 10.7. 

  Security Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form SB-2 dated 
November 9, 2007 and referred to as Exhibit 10.8. 

10.10 

  Securities Purchase Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 
2008 and referred to as Exhibit 10.10. 

10.11 

  Registration Rights Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 
2008 and referred to as Exhibit 10.11. 

10.12 

  Waiver dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 2008 and referred to as 
Exhibit 10.12. 

10.13 

  Security Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 2008 and 
referred to as Exhibit 10.13. 

10.14 

  Consent, Waiver and Agreement with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified Strategy Master 
Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. and its subsidiary dated July 30, 2009. Incorporated by reference to 
Cryoport’s Current Report on Form 8-K dated July 29, 2009 and referred to as Exhibit 10.15. 

10.15.1   Master Consulting and Engineering Services Agreement dated October 9, 2007 with KLATU Networks, LLC and CryoPort, Inc. 

Incorporated by reference to Cryoport, Inc.’s Registration Statement on Form S-8 dated March 25, 2009 and referred to as Exhibit 10.2. 

   
   
  
  
  
    
  
  
    
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
Exhibit 
No.  

Description  

10.15.2   First Amendment to Master Consulting and Engineering Services Agreement dated as of April 23, 2009, between CryoPort, Inc. and 

KLATU Networks, LLC. Incorporated by reference to Cryoport’s Registration Statement on Form S-1/A dated December 17, 2010 and 
referred to as Exhibit 10.32. 

10.15.3   Second Amendment to Master Consulting and Engineering Services Agreement dated as of November 1, 2010, between CryoPort, Inc. 
and KLATU Networks, LLC. Incorporated by reference to Cryoport’s Registration Statement on Form S-1/A dated December 17, 2010 
and referred to as Exhibit 10.33. 

10.16 

  Stock Option Agreement ISO under the 2002 Stock Incentive Plan of Cryoport Systems, Inc. Incorporated by reference to Exhibit 3.14 
to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

10.17 

  Stock Option Agreement NSO under the 2002 Stock Incentive Plan of Cryoport Systems, Inc. Incorporated by reference to Exhibit 3.15 
to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

10.18 

  2009 Stock Incentive Plan of the Company.  Incorporated by reference to Exhibit 10.21 of the Company’s Current Report on Form 8-K 
dated October 15, 2009 and referred to as Exhibit 10.21. 

10.19 

  Form Incentive Stock Option Award Agreement under the 2009 Stock Incentive Plan of the Company. Incorporated by reference to 
Exhibit 10.22 of the Company’s Current Report on Form 8-K dated October 9, 2009. 

10.20 

  Form of Non-Qualified Stock Option Award Agreement under the 2009 Stock Incentive Plan of the Company. Incorporated by 
reference to Exhibit 10.25 of the Company’s Registration Statement on Form S-8 dated April 27, 2010. 

10.21 

  2011 Stock Incentive Plan (as amended and restated).  Incorporated by reference to Exhibit B of the Company’s Definitive Proxy 
Statement on Schedule 14A filed with the SEC on July 30, 2012. 

10.22 

  Form of Stock Option Award Agreement. Incorporated by reference to Exhibit 10.37 to Cryoport’s Current Report on Form 8-K filed 
with the SEC on September 27, 2011. 

10.23 

  Form of Non-Qualified Stock Option Award Agreement. Incorporated by reference to Exhibit 10.38 to Cryoport’s Current Report on 
Form 8-K filed with the SEC on September 27, 2011. 

10.24 

  Form of Convertible Promissory Note. Incorporated by reference to Exhibit 10.24 to Cryoport’s Annual Report on Form 10-K filed with 
the SEC on June 25, 2013. 

10.25 

  Form of Amendment to Convertible Promissory Note. Incorporated by reference to Exhibit 10.25 to Cryoport’s Annual Report on Form 
10-K filed with the SEC on June 25, 2013. 

10.26 

  Form of Convertible Promissory Note. Incorporated by reference to Exhibit 10.26 to Cryoport’s Annual Report on Form 10-K filed with 
the SEC on June 25, 2013. 

10.27*    Employment Agreement between the Company and Jerrell Shelton.  Incorporated by reference to the Company’s Current Report on 

Form 8-K filed on November 6, 2012 and referred to as Exhibit 10.45. 

10.28 

  Stock Option Agreement dated November 5, 2012 between the Company and Jerrell Shelton. Incorporated by reference to Exhibit 10.28 
to Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2013. 

10.29#    Master Agreement between the Company and Federal Express Corporation dated January 1, 2013.  Incorporated by reference to the 

Company’s Current Report on Form 8-K filed on January 8, 2013 and referred to as Exhibit 10.1. 

10.30*    Employment Agreement dated June 28, 2013 with Jerrell Shelton.  Incorporated by reference to Exhibit 10.30 to Cryoport’s Current 

Report on Form 8-K filed with the SEC on July 3, 2013. 

10.31 

  Form of Convertible Promissory Notes issued with Warrants.  Incorporated by reference to Exhibit 10.31 to Cryoport’s Quarterly 
Report on Form 10-Q for the Quarter Ended September 30, 2013. 

   
   
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
Exhibit  
No.  

10.32 

10.33 

Description  

  Form of Letter of Tender and Exchange.  Incorporated by reference to Exhibit 10.32 to Cryoport’s Quarterly Report on Form 10-Q 
for the Quarter Ended September 30, 2013. 

  Form of Convertible Promissory Note (5% Bridge Note) issued with Warrants.  Incorporated by reference to Exhibit 10.33 to 
Cryoport’s Quarterly Report on Form 10-Q for the Quarter Ended December 31, 2013. 

10.34 + 

  Form of Subscription Agreement in connection with the May 2014 private placement. 

10.35+ 

  Form of Election to Convert in connection with the May 2014 private placement. 

21+ 

  Subsidiaries of Registrant. 

23.1+ 

  Consent of Independent Registered Public Accounting Firm—KMJ Corbin & Company LLP. 

31.1+ 

  Certification of Principal Executive Officer, pursuant to Rule 13a-14(a)/15d-14(a) of the Securities Exchange Act of 1934 . 

31.2+ 

  Certification of Principal Financial Officer, pursuant to Rule 13a-14(a)/15d-14(a) of the Securities Exchange Act of 1934 . 

32.1+ 

32.2+ 

  Certification of Principal Executive Officer, pursuant to Rule 13a-14(b)/15d-14(b) of the Securities Exchange Act of 1934 and 
18 U.S.C. Section 1350. 

  Certification of Principal Financial Officer, pursuant to Rule 13a-14(b)/15d-14(b) of the Securities Exchange Act of 1934 and 
18 U.S.C. Section 1350. 

101.INS†    XBRL Instance Document. 

101.SCH†   XBRL Taxonomy Extension Schema Document. 

101.CAL†   XBRL Taxonomy Extension Calculation Linkbase Document. 

101.DEF†   XBRL Taxonomy Extension Definition Linkbase Document. 

101.LAB†   XBRL Taxonomy Extension Label Linkbase Document. 

101.PRE†   XBRL Taxonomy Extension Presentation Linkbase Document. 

* 
# 

+ 
† 

Indicates a management contract or compensatory plan or arrangement. 
Confidential portions omitted and filed separately with the U.S. Securities and Exchange Commission pursuant to Rule 24b-2 promulgated 
under the Securities Exchange Act of 1934, as amended. 
Filed herewith. 
XBRL (Extensible Business Reporting Language) information is furnished and not filed or a part of a registration statement or prospectus 
for purposes of sections 11 or 12 of the Securities Act of 1933, as amended, is deemed not filed for purposes of section 18 of the Securities 
Exchange Act of 1934, as amended, and otherwise is not subject to liability under these sections or otherwise incorporated by reference. 

   
   
  
   
   
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
  
THIS  WARRANT  AND  THE  SECURITIES  ISSUABLE  UPON  EXERCISE  HEREOF  HAVE  NOT  BEEN  REGISTERED  UNDER  THE 
SECURITIES  ACT  OF  1933,  AS  AMENDED  (THE  “SECURITIES  ACT”),  OR  ANY  STATE  SECURITIES  LAW,  AND  MAY  NOT  BE 
SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF OR EXERCISED UNLESS (I) A 
REGISTRATION  STATEMENT  REGISTERING  SUCH  SECURITIES  UNDER  THE  SECURITIES  ACT  AND  APPLICABLE  STATE 
SECURITIES  LAWS  SHALL  HAVE  BECOME  EFFECTIVE,  OR  (II)  AN  EXEMPTION  FROM  REGISTRATION  UNDER  THE 
SECURITIES ACT AND OR QUALIFICATION UNDER APPLICABLE STATE SECURITIES LAWS IS AVAILABLE IN CONNECTION 
WITH SUCH OFFER, SALE OR TRANSFER.  

AN  INVESTMENT  IN  THESE  SECURITIES  INVOLVES  A  HIGH  DEGREE  OF  RISK.  HOLDERS  MUST  RELY  ON  THEIR  OWN 
ANALYSIS OF THE INVESTMENT AND ASSESSMENT OF THE RISKS INVOLVED.  

Warrant to Purchase 
_________________ shares 

Warrant Number 2014 - _________   

Exhibit 4.24 

Warrant to Purchase Common Stock  
of  
CRYOPORT, INC.  

THIS  CERTIFIES  that  ____________________  or  any  subsequent  holder  hereof  (“Holder”)  has  the  right  to  purchase  from  Cryoport,  Inc.,  a 
Nevada corporation, (the “Company”), _____________ (___________) fully paid and nonassessable shares of the Company’s common stock, 
$0.001  par  value  per  share (“Common  Stock”), subject  to  adjustment  as  provided  herein, at a  price  equal  to the  Exercise  Price  as  defined  in 
Section 3 below at any time during the Exercise Period (as defined below).  

Holder agrees with the Company that this Warrant to Purchase Common Stock of the Company (this “Warrant” or this “Agreement”) is issued 
and all rights hereunder shall be held subject to all of the conditions, limitations and provisions set forth herein.  

1. Term and Restriction on Exercise .  

The term of this Warrant begins on ___________, 2014 and the rights under this Warrant expire at 5:00 p.m., Pacific Time, on March 31, 2019 
(such period of exercise is referred to herein as the “Term”).  

Notwithstanding anything herein to the contrary, the Company shall not issue to the Holder, and the Holder may not acquire, a number of shares 
of Common Stock upon exercise of this Warrant to the extent that, upon such exercise, the number of shares of Common Stock then beneficially 
owned by the Holder and its Affiliates and any other persons or entities whose beneficial ownership of Common Stock would be aggregated with 
the Holder’s for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) (including shares held by 
any  “group”  of  which  the  Holder  is  a  member,  but  excluding  shares  beneficially  owned  by  virtue  of  the  ownership  of  securities  or  rights  to 
acquire securities that have limitations on the right to convert, exercise or purchase similar to the limitation set forth herein) would exceed 9.98% 
of the total number of shares of Common Stock then issued and outstanding (the “9.98% Cap”), provided that the 9.98% Cap shall only apply to 
the extent that the Common Stock is deemed to constitute an “equity security” pursuant to Rule 13d-1(i) promulgated under the Exchange Act. 
For purposes hereof, “group” has the meaning set forth in Section 13(d) of the Exchange Act and applicable regulations of the Securities and 
Exchange Commission (the “SEC”), and the percentage held by the Holder shall be determined in a manner consistent with the provisions of 
Section 13(d) of the Exchange Act. Upon the written request of the Holder, the Company shall, within two (2) Trading Days, confirm orally and 
in writing to the Holder the number of shares of Common Stock then outstanding.  

   
  
   
   
   
   
   
   
   
   
   
  
  
“Affiliate” means any person or entity that, directly or indirectly through one or more intermediaries, controls  or is controlled by or is  under 
common control with a person or entity, as such terms are used in and construed under Rule 144 under the Securities Act of 1933, as amended 
(the “Securities Act”). With respect to a Holder of Warrants, any investment fund or managed account that is managed on a discretionary basis 
by the same investment manager as such Holder will be deemed to be an Affiliate of such Holder.  

2. Exercise .  

(a) Manner of Exercise . During the Term (the “Exercise Period”), this Warrant may be Exercised as to all or any lesser number of whole shares 
of  Common  Stock  covered  hereby  (the  “Warrant  Shares”  or  the  “Shares”)  upon  surrender  of  this  Warrant,  with  the  Exercise  Form  attached 
hereto as Exhibit A (the “Exercise Form”) duly completed and executed, together with the full Exercise Price for each share of Common Stock 
as to which this Warrant is Exercised, at the office of the Company, Cryoport, Inc., 20382 Barrents Sea Circle, Lake Forest, California 92630; 
Fax:  (949)  470-2306,  with  an  electronic  copy  (for 
to: 
stockadministrator@cryoport.com,  or  at  such  other  office  or  agency  as  the  Company  may  designate  in  writing,  by  overnight  mail,  with  an 
advance copy of the Exercise Form sent to the Company by facsimile (such surrender and payment of the Exercise Price hereinafter called the 
“Exercise” of this Warrant).  

informational  purposes  only,  and  not  constituting  delivery  hereunder) 

(b) Date of Exercise . The “Date of Exercise” of the Warrant shall be defined as the later of (A) the date that the Exercise Form attached hereto 
as Exhibit A , completed and executed, is sent by facsimile or email to the Company, provided that the original Warrant and Exercise Form are 
received by the Company, each as soon as practicable thereafter (or, the date the original Exercise Form is received by the Company, if Holder 
has not sent advance notice by facsimile) and (B) the date that the Exercise Price is received by the Company.  

(c) Delivery of Common Stock Upon Exercise . Within three (3) business days after any Date of Exercise, the Company shall issue and deliver 
(or cause its Transfer Agent to issue and deliver) in accordance with the terms hereof to or upon the order of the Holder that number of shares of 
Common Stock (“Exercise Shares”) for the portion of this Warrant exercised as shall be determined in accordance herewith. Upon the Exercise 
of this Warrant or any part hereof, the Company shall, at its own cost and expense, take all necessary action, including obtaining and delivering 
an opinion of counsel, to assure that the Transfer Agent shall issue stock certificates in the name of Holder (or its nominee) or such other persons 
as designated by Holder and in such denominations to be specified at Exercise representing the number of shares of Common Stock issuable 
upon such Exercise.  

(d) Delivery Failure . In addition to any other remedies which may be available to the Holder, in the event that the Company fails for any reason 
to effect delivery of the Exercise Shares by the end of the Delivery Period (a “Delivery Failure”), the Holder will be entitled to revoke all or part 
of the relevant Exercise Form by delivery of a notice to such effect to the Company via facsimile or email not later than three (3) Trading Days 
after the end of the Delivery Period, whereupon the Company and the Holder shall each be restored to their respective positions immediately 
prior to the delivery of such notice, except that the liquidated damages described herein shall be payable through the date notice of revocation or 
rescission is given to the Company.  

(e) Restrictive Legend . The Holder understands that the Exercise Shares will be issued pursuant to a claimed exemption from registration under 
the Securities Act and thus the certificate for the Exercise Shares will bear a restrictive legend in substantially the following form (and a stop-
transfer order will be placed against transfer of the certificates for such securities):  

“THE  SECURITIES  REPRESENTED  BY  THIS  CERTIFICATE  HAVE  NOT  BEEN  REGISTERED  UNDER  THE  SECURITIES 
ACT  OF  1933,  AS  AMENDED,  OR  APPLICABLE  STATE  SECURITIES  LAWS.  THE  SECURITIES  MAY  NOT  BE  SOLD, 
TRANSFERRED,  ASSIGNED,  PLEDGED,  HYPOTHECATED  OR  OTHERWISE  DISPOSED  OF  IN  THE  ABSENCE  OF  AN 
EFFECTIVE REGISTRATION STATEMENT FOR THE SECURITIES UNDER SAID ACT, OR PURSUANT TO AN EXEMPTION 
FROM  REGISTRATION  UNDER  SAID  ACT  INCLUDING,  WITHOUT  LIMITATION,  PURSUANT  TO  RULES  144  OR  144A 
UNDER SAID ACT OR PURSUANT TO A PRIVATE SALE EFFECTED UNDER APPLICABLE FORMAL OR INFORMAL SEC 
INTERPRETATION OR GUIDANCE, SUCH AS A SO-CALLED “4(1) AND A HALF” SALE.”  

   
   
   
   
   
   
   
   
   
  
  
(f) Cancellation of Warrant . This Warrant shall be canceled upon the full Exercise of this Warrant and if this Warrant is not Exercised in full, 
Holder  shall  be  entitled  to  receive  a  new  Warrant  (containing  terms  identical  to  this  Warrant)  representing  any  unexercised  portion  of  this 
Warrant in addition to such Common Stock.  

(g) Holder of Record . Each person in whose name any Warrant for shares of Common Stock is issued shall, for all purposes, be deemed to be 
the Holder of record of such shares on the Date of Exercise of this Warrant, irrespective of the date of delivery of the Common Stock purchased 
upon the Exercise of this Warrant.  

3. Payment of Warrant Exercise Price .  

(a) Exercise Price . The Exercise Price (“Exercise Price”) shall initially equal $0.50 per share, subject to adjustment pursuant to the terms hereof, 
including but not limited to Section 5 below. Payment of the Exercise Price may be made in cash, bank or cashier’s check or wire transfer.  

(b)  Dispute  Resolution  .  In  the  case  of  a  dispute  as  to  the  determination  of  the  closing  price  or  the  Volume  Weighted  Average  Price  of  the 
Company’s  Common  Stock  or  the  arithmetic  calculation  of  the  Exercise  Price,  Market  Price  or  any  Major  Transaction  Warrant  Early 
Termination Price, the Company shall submit the disputed determinations or arithmetic calculations via facsimile within two (2) business days of 
receipt, or deemed receipt, of the Exercise Notice or Major Transaction Early Termination Notice, or other event giving rise to such dispute, as 
the  case  may  be,  to  the  Holder.  If  the  Holder  and  the  Company  are  unable  to  agree  upon  such  determination  or  calculation  within  two  (2) 
business days of such disputed determination or arithmetic calculation being submitted to the Holder, then the Company shall, within two (2) 
business days submit via facsimile (i) the disputed determination of the closing price or the Volume Weighted Average Price of the Company’s 
Common Stock to an independent, reputable investment bank selected by the Company and approved by the Holder, which approval shall not be 
unreasonably  withheld  or  (ii) the  disputed  arithmetic  calculation  of  the Exercise Price,  Market Price  or  any Major  Transaction Warrant  Early 
Termination Price to the Company’s independent, outside accountant. The Company shall cause the investment bank or the accountant, as the 
case may be, to perform the determinations or calculations and notify the Company and the Holder of the results no later than five (5) business 
days  from  the  time  such  investment  bank  or  accountant,  as  the  case  may  be,  receives  the  disputed  determinations  or  calculations.  Such 
investment bank’s or accountant’s determination or calculation, as the case may be, shall be binding upon all parties absent demonstrable error.  

4. Transfer Rights . Subject to the provisions of Section 8 of this Warrant, this Warrant may be transferred on the books of the Company, in 
whole or in part, in person or by attorney, upon surrender of this Warrant properly completed and endorsed. This Warrant shall be canceled upon 
such surrender and, as soon as practicable thereafter, the person to whom such transfer is made shall be entitled to receive a new Warrant or 
Warrants as to the portion of this Warrant transferred, and Holder shall be entitled to receive a new Warrant as to the portion hereof retained.  

5. Adjustments Upon Certain Events .  

(a) Participation . The Holder, as the holder of this Warrant, shall be entitled to receive such dividends paid and distributions of any kind made 
to the holders of Common Stock of the Company to the same extent as if the Holder had Exercised this Warrant into Common Stock (without 
regard to any limitations on exercise herein or elsewhere and without regard to whether or not a sufficient number of shares are authorized and 
reserved  to  effect  any  such  exercise  and  issuance)  and  had  held  such  shares  of  Common  Stock  on  the  record  date  for  such  dividends  and 
distributions. Payments under the preceding sentence shall be made concurrently with the dividend  or distribution to the holders of Common 
Stock.  

(b)  Recapitalization  or  Reclassification  .  If  the  Company  shall  at  any  time  effect  a  stock  split,  payment  of  stock  dividend,  recapitalization, 
reclassification or other similar transaction of such character that the shares of Common Stock shall be changed into or become exchangeable for 
a larger or smaller number of shares, then upon the effective date thereof, the number of shares of Common Stock which Holder shall be entitled 
to purchase upon Exercise of this Warrant shall be increased or decreased, as the case may be, in direct proportion to the increase or decrease in 
the  number  of shares  of  Common  Stock  by  reason  of  such  stock  split,  payment  of  stock  dividend,  recapitalization, reclassification  or  similar 
transaction,  and  the  Exercise  Price  shall  be,  in  the  case  of  an  increase  in  the  number  of  shares,  proportionally  decreased  and,  in  the  case  of 
decrease in the number of shares, proportionally increased. The Company shall give Holder the same notice it provides to holders of Common 
Stock of any transaction described in this Section 5(b).  

   
   
   
   
   
   
   
   
   
   
  
  
(c) Rights Upon Major Transaction .  

(i) Major Transaction . In the event that a Major Transaction (as defined below) occurs, then (1) in the case of a Cash-Out Major Transaction and 
in the case of a Mixed Major Transaction to the extent of the percentage of the cash consideration in the Mixed Major Transaction (determined 
in  accordance  with  the  definition  of  a  Mixed  Major  Transaction  below),  the  Holder,  at  its  option,  may  require  the  Company  to  redeem  the 
Holder’s outstanding Warrants in accordance with Section 5(c)(iii) below, and (2) in the case of a transaction with a Publicly Traded Successor 
Entity  covered  by  the  provisions  of  Section  5(c)(i)(A)  below  in  which  the  Company  is  not  the  surviving  entity  (a  “Successor  Redemption 
Transaction”) and in the case of a Mixed Major Transaction that is a Successor Redemption Transaction, to the extent of the percentage of the 
consideration represented by securities of a Publicly Traded Successor Entity, the Holder may require this Warrant to be treated as a Successor 
Redemption in accordance with Section 5(c)(iii) below. In the event the Holder shall not have exercised any of its rights under clauses (1) or (2) 
above within the applicable time periods set forth herein, then the Major Transaction shall be treated as an Assumption (as defined below) in 
accordance with Section 5(c)(ii) below unless the Holder waives its rights under this Section 5(c) with respect to such Major Transaction. Each 
of the following events shall constitute a “Major Transaction”:  

(A)  a  consolidation,  merger,  exchange  of  shares,  recapitalization,  reorganization,  business  combination  or  other  similar  event,  (1) following 
which the holders of Common Stock immediately preceding such consolidation, merger, exchange, recapitalization, reorganization, combination 
or event either (a) no longer hold a majority of the shares of Common Stock or (b) no longer have the ability to elect a majority of the board of 
directors of the Company or (2) as a result of which shares of Common Stock shall be changed into (or the shares of Common Stock become 
entitled  to  receive)  the  same  or  a  different  number  of  shares  of  the  same  or  another  class  or  classes  of  stock  or  securities  of  another  entity 
(collectively, a “Change of Control Transaction”);  

(B) the sale or transfer, in one transaction or in a series of related transactions, of significant assets of the Company which, without limitation, 
shall include, but not be limited to, a sale or transfer, in one transaction or in a series of related transactions, of more than 50% of the Company’s 
assets as reflected on its then latest publicly filed balance sheet (including proprietary rights), provided, however, that except for a sale of all or 
substantially  all  of  the  Company’s  assets,  a  collaborative  arrangement,  licensing  agreement,  joint  venture  or  partnership  or  similar  business 
arrangement  providing  for  the  development  or  commercial  exploitation  or,  or  right  to  develop  or  commercially  exploit,  the  technology, 
intellectual  property  or  products  of  the  Company  (including  arrangements  that  involve  the  assignment  or  licensing  of  any  existing  or  newly 
developed intellectual property under such arrangements) whereby income or profits are to be shared (including by lump sum royalty or running 
royalty) with any other entity shall not constitute a Major Transaction;  

(C) a purchase, tender or exchange offer made to the holders of outstanding shares of Common Stock, such that following such purchase, tender 
or exchange offer a Change of Control Transaction shall have occurred;  

(D) the liquidation, bankruptcy, insolvency, dissolution or winding-up (or the occurrence of any analogous proceeding) affecting the Company; 
or  

(E) the shares of Common Stock cease to be listed, traded or publicly quoted on the OTCBB, and are not promptly re-listed or requoted on either 
the New York Stock Exchange, the NYSE Alternext U.S., the NASDAQ Global Select Market, the NASDAQ Capital Market or listed in the 
over the counter market by the Financial Industry Regulatory Authority, Inc. or in the “pink sheets” by the Pink OTC Market, Inc.  

   
   
   
   
   
   
   
   
  
  
(ii) Assumption. The Company shall not enter into or be party to a Major Transaction that is to be treated as an Assumption pursuant to Section 5
(c)(i), unless (i) any Person purchasing the Company’s assets or Common Stock, or any successor entity resulting from such Major Transaction 
(in each case, a “Successor Entity”), assumes in writing all of the obligations of the Company under this Warrant, and (ii) pursuant to written 
agreements in form and substance satisfactory to the Holder and approved by the Holder prior to such Major Transaction, including agreements 
to  deliver  to  each  holder  of  Warrants  in  exchange  for  such  Warrants  a  security  of  the  Successor  Entity  evidenced  by  a  written  instrument 
substantially similar in form and substance to the Warrants, including, without limitation, an instrument representing the appropriate number of 
shares of the Successor Entity, having similar exercise rights as the Warrants (including but not limited to a similar Exercise Price and similar 
Exercise Price  adjustment  provisions based on the price  per share  or conversion ratio to be received by  the  holders of Common Stock in  the 
Major Transaction), satisfactory to the Holder. Upon the occurrence of any Major Transaction, any Successor Entity shall succeed to, and be 
substituted for (so that from and after the date of such Major Transaction, the provisions of this Warrant referring to the “Company” shall refer 
instead to the Successor Entity), and may exercise every right and power of the Company and shall assume all of the obligations of the Company 
under this Warrant with the same effect as if such Successor Entity had been named as the Company herein. Upon consummation of the Major 
Transaction, the Successor Entity shall deliver to the Holder confirmation that there shall be issued upon exercise or redemption of this Warrant 
at any time after the consummation of the Major Transaction, in lieu of the shares of Common Stock (or other securities, cash, assets or other 
property) issuable upon the exercise of the Warrants prior to such Major Transaction, such shares of common stock (or their equivalent) of the 
Successor Entity, as adjusted in accordance with the provisions of this Warrant. The provisions of this Section shall apply similarly and equally 
to successive Major Transactions and shall be applied without regard to any limitations on the exercise of this Warrant other than any applicable 
beneficial ownership limitations. Any assumption of Company obligations under this paragraph shall be referred to herein as an “Assumption.”  

(iii) Notice; Major Transaction Early Termination Right. At least thirty (30) days prior to the consummation of any Major Transaction, but, in 
any event, on the first to occur of (x) the date of the public announcement of such Major Transaction if such announcement is made before 4:00 
p.m., New York City time, or (y) the day following the public announcement of such Major Transaction if such announcement is made on and 
after  4:00  p.m.,  New  York  City  time,  the  Company  shall  deliver  written  notice  thereof  via  facsimile  and  overnight  courier  to  the  Holder  (a 
“Major Transaction Notice”). At any time during the period beginning after the Holder’s receipt of a Major Transaction Notice and ending five 
(5) Trading Days prior to the consummation of such Major Transaction (the “Early Termination Period”), the Holder may require the Company 
to redeem (an “Early  Termination  Upon  Major Transaction”)  all  or  any  portion of this Warrant  (without  taking  into  consideration  the  9.98% 
Cap)  by  delivering  written  notice  thereof  (“Major  Transaction  Early  Termination  Notice”)  to  the  Company,  which  Major  Transaction  Early 
Termination Notice shall indicate the portion of the principal amount (the “Early Termination Principal Amount”) of the Warrant that the Holder 
is  electing  to  have  redeemed.  The  portion  of  this  Warrant  subject  to  early  termination  pursuant  to  this  Section 5(c)(iii)  (the  “Redeemable 
Shares”), shall be redeemed by the Company at a price (the “Major Transaction Warrant Early Termination Price”) payable in cash equal to the 
Black  Scholes  Value  of  the  Redeemable  Shares  determined  by  use  of  the  Black  Scholes  Option  Pricing  Model  using  the  criteria  set  forth  in 
Schedule 1 hereto (the “Black Scholes Value”).  

At any time during the Early Termination Period, the Holder may require the Company to treat all or any portion of this Warrant eligible to be 
treated as a Successor Redemption (without taking into consideration the 9.98% Cap) as a Successor Redemption by delivering written notice 
thereof  (a  “Successor  Redemption  Notice”)  to  the  Company,  which  Successor  Redemption  Notice  shall  indicate  the  portion  of  the  principal 
amount of the Warrant that the Holder is electing to have treated as a Successor Redemption. The portion of this Warrant subject to Successor 
redemption  pursuant  to  this  Section  5(c)(iii)  (the  “Successor  Redemption  Shares”),  shall  be  converted  upon  consummation  of  such  Major 
Transaction into the number of securities of the Successor Entity (the “Successor Redemption Shares”) that would be issuable under the terms of 
such Major Transaction in respect of a number of shares of Common Stock equal to the Black Scholes Share Amount.  

(iv) Escrow; Payment of Major Transaction Warrant Early Termination Price . Following the receipt of a Major Transaction Early Termination 
Notice from the Holder, the Company shall not effect a Major Transaction that is being treated as an early termination unless (a) the definitive 
documentation governing such Major Transaction provides that it shall be a condition precedent to the consummation of such Major Transaction 
that  the  Holder  be  issued  or  paid,  as  the  case  may  be,  an  amount  in  shares  of  Common  Stock  or  cash,  as  applicable,  equal  to  the  Major 
Transaction  Warrant  Early  Termination  Price  and/or  applicable  Exercise  Shares  or  (b) it  shall  first  place  into  an  escrow  account  with  an 
independent escrow agent, at least three (3) business days prior to the closing date of the Major Transaction (the “Major Transaction Escrow 
Deadline”), an amount in shares of Common Stock (or irrevocable instructions to the Transfer Agent to issue such shares) or cash, as applicable, 
equal to the Major Transaction Warrant Early Termination Price and/or applicable Exercise Shares. Concurrently upon closing of such Major 
Transaction, the Company shall pay or shall instruct the escrow agent to pay the Major Transaction Warrant Early Termination Price and/or to 
deliver the applicable Exercise Shares to the Holder. For purposes of determining the amount required to be placed in escrow pursuant to the 
provisions  of  this  subsection  (iv) and  without  affecting  the  amount  of  the  actual  Major  Transaction  Warrant  Early  Termination  Price  and/or 
applicable Exercise Shares, the calculation of the price referred to in clause (1) of the first column of Schedule 1 hereto with respect to Stock 
Price shall be determined based on the Closing Market Price (as defined on Schedule I) of the Common Stock on the Trading Day immediately 
preceding the date that the funds and/or applicable Exercise Shares, as applicable, are deposited with the escrow agent.  

   
   
   
   
   
  
  
Following the receipt of a Successor Redemption Notice, the Company shall not effect the applicable Major Transaction unless the definitive 
documentation governing such Major Transaction includes an obligation by the Successor Entity to issue the Successor Redemption Shares to 
the Holder upon consummation of the Major Transaction and designates the Holder as an express third party beneficiary of such obligation.  

(v) Injunction . Following the receipt of a Major Transaction Early Termination Notice from the Holder, in the event that the Company attempts 
to  consummate  a  Major  Transaction  without  either  placing  the  Major  Transaction  Warrant  Early  Termination  Price  or  applicable  Exercise 
Shares,  as  applicable,  in  escrow  in  accordance  with  subsection  (iv)  above  or  without  payment  of  the  Major  Transaction  Warrant  Early 
Termination Price or issuance of the applicable Exercise Shares, as applicable, to the Holder prior to consummation of such Major Transaction, 
or without providing for the issuance of Successor Redemption Shares in accordance with Section 5(c) above, as applicable, the Holder shall 
have  the right to  apply for  an injunction  in any  state or federal  courts sitting in  the  City  of  New  York, borough  of  Manhattan  to prevent  the 
closing  of  such  Major  Transaction  until  the  Major  Transaction  Warrant  Early  Termination  Price  is  paid  to  the  Holder,  in  full,  the  applicable 
Exercise Shares are delivered or the issuance of the Successor Redemption Shares is provided for, as applicable.  

An  early  termination  required  by  this  Section 5(c)  shall  be  made  in  accordance  with  the  provisions  of  Section 12  and  shall  have  priority  to 
payments to holders of Common Stock in connection with a Major Transaction to the extent an early termination required by this Section 5(c)
(iii) are deemed or determined by a court of competent jurisdiction to be prepayments of the Warrant by the Company, such early termination 
shall be deemed to be voluntary prepayments. Notwithstanding anything to the contrary in this Section 5, until the Major Transaction Warrant 
Early Termination Price is paid in full or the Successor Redemption Shares are fully issued, as applicable, this Warrant may be exercised, in 
whole  or  in  part,  by  the  Holder  into  shares  of  Common  Stock,  or  in  the  event  the  Exercise  Date  is  after  the  consummation  of  the  Major 
Transaction or in the event of a Successor Redemption, shares of  publicly traded common stock (or their equivalent) of the Successor Entity 
pursuant to Section 5(c). The parties hereto agree that in the event of the Company’s early termination of any portion of the Warrant under this 
Section 5(c), the Holder’s damages would be uncertain and difficult to estimate because of the parties’ inability to predict future interest rates 
and the uncertainty of the availability of a suitable substitute investment opportunity for the Holder. Accordingly, any premium due under this 
Section 5(c) is intended by the parties to be, and shall be deemed, a reasonable estimate of the Holder’s actual loss of its investment opportunity 
and not as a penalty.  

For purposes hereof:  

“Cash-Out Major Transaction” means a Major Transaction in which the consideration payable to holders of Common Stock in connection with 
the Major Transaction consists solely of cash.  

“Eligible  Market”  means  the  OTCBB,  the  New  York  Stock  Exchange,  Inc.,  the  NYSE  Arca,  the  NASDAQ  Capital  Market,  the  NASDAQ 
Global Market, the NASDAQ Global Select Market or the NYSE Alternext U.S.  

“Mixed Major Transaction” means a Major Transaction in which the consideration payable to the shareholders of the Company consists partially 
of  cash  and  partially  of  securities  of  a  Successor  Entity.  If  the  Successor  Entity  is  a  Publicly  Traded  Successor  Entity,  the  percentage  of 
consideration  represented  by  securities  of  such  Successor  Entity  shall  be  equal  to  the  percentage  that  the  value  of  the  aggregate  anticipated 
number of shares of the Publicly Traded Successor Entity to be issued to holders of Common Stock of the Company represents in comparison to 
the  aggregate  value  of  all  consideration,  including  cash  consideration,  in  such  Mixed  Major  Transaction,  as  such  values  are  set  forth  in  any 
definitive  agreement  for  the  Mixed  Major  Transaction  that  has  been  executed  at  the  time  of  the  first  public  announcement  of  the  Major 
Transaction or, if no such value is determinable from such definitive agreement, based on the closing market price for shares of the Publicly 
Traded Successor Entity on its principal securities exchange on the Trading Day preceding the first public announcement of the Mixed Major 
Transaction. If the Successor Entity is a Private Successor Entity, the percentage of consideration represented by securities of such Successor 
Entity shall be determined in good-faith by the Company's Board of Directors  

   
   
   
   
   
   
   
   
  
  
“Parent Entity” of a Person means an entity that, directly or indirectly, controls the applicable Person and whose common stock or equivalent 
equity security is quoted or listed on an Eligible Market, or, if there is more than one such Person or Parent Entity, the Person or Parent Entity 
with the largest public market capitalization as of the date of consummation of a Major Transaction.  

“Person” means an individual, a limited liability company, a partnership, a joint venture, a corporation, a trust, an unincorporated organization, 
any other entity and a government or any department or agency thereof.  

“Private Successor Entity” means a Successor Entity that is not a Publicly Traded Successor Entity.  

“Publicly Traded Successor Entity” means a Successor Entity that is a publicly traded corporation whose common stock is quoted on or listed for 
trading on an Eligible Market (as defined above).  

“Successor Entity” means any Person purchasing the Company’s assets or Common Stock, or any successor entity resulting from such Major 
Transaction, or if the Warrant is to be exercisable for shares of capital stock of its Parent Entity (as defined above), its Parent Entity.  

(d) Exercise Price Adjusted . As used in this Warrant, the term “Exercise Price” shall mean the purchase price per share specified in Section 3(a) 
of this Warrant, until the occurrence of an event stated in this Section 5 or otherwise set forth in this Warrant, and thereafter shall mean said 
price as adjusted from time to time in accordance with the provisions of said subsection. No adjustment made pursuant to any provision of this 
Section 5 shall have the net effect of increasing the aggregate Exercise Price in relation to the split adjusted and distribution adjusted price of the 
Common Stock.  

(e)  Adjustments:  Additional  Shares,  Securities  or  Assets  .  In  the  event  that  at  any  time,  as  a  result  of  an  adjustment  made  pursuant  to  this 
Section 5 or otherwise, Holder shall, upon Exercise of this Warrant, become entitled to receive shares and/or other securities or assets (other than 
Common Stock) then, wherever appropriate, all references herein to shares of Common Stock shall be deemed to refer to and include such shares 
and/or other securities or assets; and thereafter the number of such shares and/or other securities or assets shall be subject to adjustment from 
time to time in a manner and upon terms as nearly equivalent as practicable to the provisions of this Section 5.  

(f) Notice of Adjustments . Whenever the Exercise Price is adjusted pursuant to the terms of this Warrant, the Company shall promptly mail to 
the Holder a notice (an “Exercise Price Adjustment Notice”) setting forth the Exercise Price after such adjustment and setting forth a statement 
of  the  facts requiring  such  adjustment. The Company shall, upon the written request at any time of the Holder, furnish to such Holder a like 
Warrant setting forth (i) such adjustment or readjustment, (ii) the Exercise Price at the time in effect and (iii) the number of shares of Common 
Stock and the amount, if any, of other securities or property which at the time would be received upon Exercise of the Warrant. For purposes of 
clarification, whether or not the Company provides an Exercise Price Adjustment Notice pursuant to this Section 5(f), upon the occurrence of 
any event that leads to an adjustment of the Exercise Price, the Holder would be entitled to receive a number of Exercise Shares based upon the 
new  Exercise  Price,  as  adjusted,  for  exercises  occurring  on  or  after  the  date  of  such  adjustment,  regardless  of  whether  the  Holder  accurately 
refers to the adjusted Exercise Price in the Exercise Form.  

   
   
   
   
   
   
   
   
   
  
  
6. Fractional Interests .  

No fractional shares or scrip representing fractional shares shall be issuable upon the Exercise of this Warrant, but on Exercise of this Warrant, 
Holder may purchase only a whole number of shares of Common Stock. If, on Exercise of this Warrant, Holder would be entitled to a fractional 
share of Common Stock or a right to acquire a fractional share of Common Stock, such fractional share shall be disregarded and the number of 
shares of Common Stock issuable upon Exercise shall be the next higher whole number of shares.  

7. Reservation of Shares .  

From and after the date hereof, the Company shall at all times reserve for issuance such number of authorized and unissued shares of Common 
Stock (or other securities substituted therefor as herein above provided) as shall be sufficient for the Exercise of this Warrant and payment of the 
Exercise  Price.  If  at  any  time  the  number  of  shares  of  Common  Stock  authorized  and  reserved  for  issuance  is  below  the  number  of  shares 
sufficient  for  the  Exercise  of  this  Warrant  (a  “Share  Authorization  Failure”)  (based  on  the  Exercise  Price  in  effect  from  time  to  time),  the 
Company will promptly take all corporate action necessary to authorize and reserve a sufficient number of shares, including, without limitation, 
calling a special meeting of stockholders to authorize additional shares to meet the Company’s obligations under this Section 7, in the case of an 
insufficient number of authorized shares, and using its best efforts to obtain stockholder approval of an increase in such authorized number of 
shares. The Company covenants and agrees that upon the Exercise of this Warrant, all shares of Common Stock issuable upon such Exercise 
shall be duly and validly issued, fully paid and nonassessable and not subject to preemptive rights, rights of first refusal or similar rights of any 
Person.  

8. Restrictions on Transfer .  

(a)  Registration  or  Exemption  Required  .  This  Warrant  has  been  issued  in  a  transaction  exempt  from  the  registration  requirements  of  the 
Securities Act by virtue of Regulation D and exempt from state registration or qualification under applicable state laws. None of the Warrant or 
the  Exercise  Shares  may  be  pledged,  transferred,  sold,  assigned,  hypothecated  or  otherwise  disposed  of  except  pursuant  to  an  effective 
registration  statement  or  an  exemption  to  the  registration  requirements  of  the  Securities  Act  and  applicable  state  laws  including,  without 
limitation, a so-called “4(1) and a half” transaction.  

(b) Assignment . Should the Holder desire to sell, transfer, assign, pledge, hypothecate or otherwise dispose of this Warrant, in whole or in part; 
the Holder shall deliver a written notice to Company, substantially in the form of the Assignment attached hereto as Exhibit B , indicating the 
Person or Persons to whom the Warrant is requested to be assigned and the respective number of Warrant Shares to be assigned to each assignee. 
The Company may permit the assignment upon such reasonable conditions as the Company may require, including the delivery to the Company 
of  an  acceptable  opinion  of  counsel  as  to  the  assignment’s  qualification  for  an  exemption  from  registration.  This  Warrant  and  the  rights 
evidenced hereby shall inure to the benefit of and be binding upon the successors and permitted assigns of the Holder.  

(c)  Representations  of  the  Holder.  The  right  to  acquire  Common  Stock  or  the  Common  Stock  issuable  upon  exercise  of  the  Holder’s  rights 
contained herein will be acquired for investment and not with a view to the sale or distribution of any part thereof, and the Holder has no present 
intention of selling, transferring, assigning, pledging, hypothecating or otherwise disposing of this Warrant in any public distribution of the same 
except  pursuant  to  a  registration  or  exemption.  Holder  is  an  “accredited  investor”  within  the  meaning  of  the  Securities  and  Exchange 
Commission’s Rule 501 of Regulation D, as presently in effect. The Holder understands (i) that the Common Stock issuable upon exercise of the 
Holder’s rights contained herein is not registered under the Securities Act or qualified under applicable state securities laws on the ground that 
the  issuance  contemplated  by  this  Warrant  will  be  exempt  from  the  registration  and  qualifications  requirements  thereof  and  (ii)  that  the 
Company’s reliance on such exemption is predicated on the representations set forth in this Section 8(c). The Holder has such knowledge and 
experience in financial and business matters as to be capable of evaluating the merits and risks of its investment and has the ability to bear the 
economic risks of its investment.  

   
   
   
   
   
   
   
   
   
  
  
9. Noncircumvention .  

The Company hereby covenants and agrees that the Company will not, by amendment of its certificate of incorporation, bylaws or through any 
reorganization, transfer of assets, consolidation, merger, scheme of arrangement, dissolution, issue or sale of securities, or any other voluntary 
action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant, and will at all times in good faith carry out all 
the provisions of this Warrant and take all action as may be required to protect the rights of the Holder. Without limiting the generality of the 
foregoing, the Company (i) shall not increase the par value of any shares of Common Stock receivable upon the exercise of this Warrant above 
the Exercise Price then in effect, and (ii) shall take all such actions as may be necessary or appropriate in order that the Company may validly 
and legally issue fully paid and nonassessable shares of Common Stock upon the exercise of this Warrant.  

10. Benefits of this Warrant .  

Nothing in this Warrant shall be construed to confer upon any person other than the Company and Holder any legal or equitable right, remedy or 
claim under this Warrant and this Warrant shall be for the sole and exclusive benefit of the Company and Holder.  

11. Governing Law .  

All questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be governed by and construed and 
enforced in accordance with the internal laws of the State of California, without regard to the principles of conflicts of law thereof. Each party 
agrees  that  all legal  proceedings concerning the  interpretations,  enforcement  and  defense  of the  transactions contemplated  by  this  Agreement 
(whether brought against a party hereto or its respective affiliates, directors, officers, shareholders, employees or agents) shall be commenced 
exclusively in the state and federal courts sitting in Los Angeles, California. Each party hereby irrevocably submits to the exclusive jurisdiction 
of the state and federal courts sitting in such city for the adjudication of any dispute hereunder or in connection herewith or with any transaction 
contemplated hereby or discussed herein, and hereby irrevocably waives, and agrees not to assert in any suit, action or proceeding, any claim that 
it is not personally subject to the jurisdiction of any such court, that such suit, action or proceeding is improper or is an inconvenient venue for 
such proceeding. Each party hereby irrevocably waives personal service of process and consents to process being served in any such suit, action 
or proceeding by mailing a copy thereof via registered or certified mail or overnight delivery (with evidence of delivery) to such party at the 
address in effect for notices to it under this Agreement and agrees that such service shall constitute good and sufficient service of process and 
notice thereof. Nothing contained herein shall be deemed to limit in any way any right to serve process in any other manner permitted by law. 
The parties hereby waive all rights to a trial by jury. If either party shall commence an action or proceeding to enforce any provisions of this 
Agreement, then the prevailing party in such action or proceeding shall be reimbursed by the other party for its reasonable attorneys’ fees and 
other costs and expenses incurred with the investigation, preparation and prosecution of such action or proceeding.  

12. Loss of Warrant .  

Upon  receipt  by  the  Company  of  evidence  of  the  loss,  theft,  destruction  or  mutilation  of  this  Warrant,  and  (in  the  case  of  loss,  theft  or 
destruction) of indemnity or security reasonably satisfactory to the Company, and upon surrender and cancellation of this Warrant, if mutilated, 
the Company shall execute and deliver a new Warrant of like tenor and date.  

13. Notice or Demands .  

Notices or demands pursuant to this Warrant to be given or made by Holder to or on the Company shall be sufficiently given or made if sent by 
certified  or  registered  mail,  return  receipt  requested,  postage  prepaid,  and  addressed,  until  another  address  is  designated  in  writing  by  the 
Company, to the address set forth in Section 2(a) above. Notices or demands pursuant to this Warrant to be given or made by the Company to or 
on Holder shall be sufficiently given or made if sent by certified or registered mail, return receipt requested, postage prepaid, and addressed, to 
the address of Holder set forth in the Company’s records, until another address is designated in writing by Holder.  

   
   
   
   
   
   
   
   
   
   
   
  
  
IN WITNESS WHEREOF, the undersigned has executed this Warrant as of the _____ day of ______, 2013.  

CRYOPORT, INC . 

By:      

Title: 

EXHIBIT A  

EXERCISE FORM FOR WARRANT  

TO: [                                   ]  

(cid:1) Exercise  

The undersigned hereby irrevocably exercises the attached warrant (the “Warrant”) with respect to shares of Common Stock (the “Common 
Stock”) of Cryoport, Inc., a Nevada corporation (the “Company”).  

The undersigned hereby encloses $____ as payment of the Exercise Price.  

1.  The  undersigned  requests  that  any  stock  certificates  for  such  shares  be  issued  and,  if  applicable,  a  warrant  representing  any  unexercised 
portion hereof be issued, pursuant to the Warrant in the name of the undersigned and delivered to the undersigned at the address set forth below.  

2. Capitalized terms used but not otherwise defined in this Exercise Form shall have the meaning ascribed thereto in the Warrant.  

Dated: _______________  

Signature 

Print Name 

Address 

NOTICE  

The signature to the foregoing Exercise Form must correspond to the name as written upon the face of the attached Warrant in every particular, 
without alteration or enlargement or any change whatsoever.  

   
   
   
   
   
   
   
    
   
   
   
    
   
   
  
  
  
  
  
  
  
  
   
   
  
  
  
  
  
  
EXHIBIT B  

ASSIGNMENT  

(To be executed by the registered holder  
desiring to transfer the Warrant)  

FOR VALUE RECEIVED, the undersigned holder of the attached warrant (the “Warrant”) hereby sells, assigns and transfers unto the person or 
persons below named the right to purchase __________ shares of the Common Stock of Cryoport, Inc., a Nevada corporation, evidenced by the 
attached Warrant and does hereby irrevocably constitute and appoint __________ attorney to transfer the said Warrant on the books of the 
Company, with full power of substitution in the premises.  

Dated: _______________ 

Fill in for new registration of Warrant:  

Signature 

Name 

Address 

Please print name and address of assignee 
(including zip code number) 

NOTICE  

The signature to the foregoing Assignment must correspond to the name as written upon the face of the attached Warrant in every particular, 
without alteration or enlargement or any change whatsoever.  

   
   
   
   
   
    
   
    
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
Remaining Term 

Interest Rate 

Volatility 

Schedule 1  

Black-Scholes Value  

Calculation Under Section 5(c)(iii)  

Number of calendar days from date of public announcement of the Major Transaction after 
commencement of the Exercise Period until the last date on which the Warrant may be exercised. 

A risk-free interest rate corresponding to the US$ LIBOR/Swap rate for a period equal to the Remaining 
Term. 

If the first public announcement of the Major  
Transaction is made at or prior to 4:00 p.m., New  
York City time, the arithmetic mean of the historical  
volatility for the 10, 30 and 50 Trading Day periods  
ending on the date of such first public  
announcement, obtained from the HVT or similar  
function on Bloomberg.  

If the first public announcement of the Major  
Transaction is made after 4:00 p.m., New York City  
time, the arithmetic mean of the historical volatility for the  
10, 30 and 50 Trading Day periods ending on the  
next succeeding Trading Day following the date of  
such first public announcement, obtained from the  
HVT or similar function on Bloomberg.  

Stock Price 

The greater of (1) the closing price of the Common Stock on the OTCBB, or, if that is not the principal 
trading market for the Common Stock, such principal market on which the Common Stock is traded or 
listed (the “Closing Market Price”) on the trading day immediately preceding the date on which a Major 
Transaction is consummated, (2) the first Closing Market Price following the first public announcement 
of a Major Transaction, or (3) the Closing Market Price as of the date immediately preceding the first 
public announcement of the Major Transaction. 

Dividends 

Strike Price 

Zero. 

Exercise Price as defined in section 3(a). 

12 

   
   
   
   
   
   
  
  
  
  
  
 
   
  
  
  
  
  
  
Exhibit 10.34 

IMPORTANT: PLEASE READ CAREFULLY BEFORE SIGNING  
SIGNIFICANT REPRESENTATIONS ARE CALLED FOR HEREIN  

SUBSCRIPTION AGREEMENT AND LETTER OF INVESTMENT INTENT  

The undersigned hereby tenders this subscription and applies for the purchase of Units, consisting of a share of Class A Convertible 
Preferred  Stock  and  a  Warrant  for  the  purchase  of  Common  Stock  (“the  Securities  ”)  of  Cryoport,  Inc.  (the  “  Company  ”),  in  the  amount 
indicated on the signature page hereof, upon the terms and conditions set forth below.  

Subscription payment is by:  

_____ 

_____ 

A check in the amount of the subscription payable to “Cryoport Escrow” 

A wire transfer in the amount of the subscription sent to: 

Receiving Bank: 
Address: 

United Bankers Bank 
1650 W 82 nd Street 
Bloomington, MN 55431 

United Bankers Bank Routing/ABA # 091001322 

To Credit: 
Address: 

Signature Bank 
9800 Bren Road E Suite 200 
Minnetonka, MN 55343 

Account Number: 

2503167 

Final Credit: 
Account name: 
Account # 

Cryoport Escrow 
10062378 

The undersigned understands that the Company has the right to reject any subscription for the Securities for any reason and that the 
Company  will  cause  to  be  returned  the  funds  delivered  herewith  if  this  subscription  is  rejected.  By  execution  below,  the  undersigned 
acknowledges that the Company is relying upon the accuracy and completeness of the representations contained herein in complying with its 
obligations under applicable securities laws.  

1.  Subscription . 

(a) 

Subject  to  the  terms  and  conditions  of  this  subscription  agreement  and  letter  of  investment  intent  (the  “  Subscription 
Agreement ”), the undersigned hereby irrevocably subscribes for the Securities for the aggregate purchase price set forth on the 
signature page hereto, which is payable as indicated above. The purchase price for one share of Class A Convertible Preferred 
Stock and a warrant to purchase eight shares of Common Stock at an exercise price of $0.50 per share (the “ Warrant ”) shall 
equal  $12.00  (the  “  Per  Unit  Purchase  Price  ”).  No  fractional  shares  will  be  issued.  If  the  subscription  amount  yields  a 
fractional share of 0.5 or more, the number of shares will be rounded up and all other fractional shares will be rounded down. 

   
  
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
(b) 

(c) 

(d) 

The  Class  A  Convertible  Preferred  Stock  will  be  issued  pursuant  to  the  terms  and  conditions  set  forth  in  the  certificate  of 
designation  (“  Certificate  of  Designation  ”)  that  will  be  filed  with  the  Secretary  of  State  of  Nevada  on  or  before  the  first 
closing  in  connection  with  the  offering  of  the  Securities.  The  Warrant  will  be  issued  pursuant  to  the  terms  and  conditions 
contained in the Warrant Agreement (the “ Warrant Agreement ”). 

If  the  Company  accepts  this  subscription,  closing  shall  take  place  at  such  date,  time,  and  location  as  determined  by  the 
Company.  In  the  discretion  of  the  Company,  there  may  be  more  than  one  closing  in  connection  with  the  offering  of  the 
Securities.  The  Securities  sold  in  a  subsequent  closing,  if  any,  shall  be  sold  at  the  same  Per  Unit  Purchase  Price  as  the 
Securities sold in the initial closing. 

THE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR THE SECURITIES 
LAWS  OF  ANY  STATE  OR  ANY  OTHER  JURISDICTION.  THERE  ARE  FURTHER  RESTRICTIONS  ON  THE 
TRANSFERABILITY  OF  THE  SECURITIES  DESCRIBED  HEREIN.  THE  PURCHASE  OF  THE  SECURITIES 
INVOLVES  A  HIGH  DEGREE  OF  RISK  AND  SHOULD  BE  CONSIDERED  ONLY  BY  PERSONS  WHO  CAN  BEAR 
THE RISK OF THE LOSS OF THEIR ENTIRE INVESTMENT. 

2.  Subscribers Representations . The undersigned acknowledges and represents as follows: 

(a) 

(b) 

(c) 

The  undersigned  has  received,  and  is  familiar  with  the  Company’s  Private  Placement  Memorandum  dated  March  5,  2014,  the 
Certificate  of  Designation,  the  Warrant  Agreement,  and  the  publicly  available  filings  by  the  Company  with  the  Securities  Exchange 
Commission (collectively the “ Disclosure Documents ”). 

The undersigned is in a financial position to hold the Securities for an indefinite period of time and is able to bear the economic risk and 
withstand a complete loss of its investment in the Securities. 

The  undersigned  believes  it,  either  alone  or  with  the  assistance  of  its  professional  advisor,  has  such  knowledge  and  experience  in 
financial and business matters that  it  is  capable  of  reading  and  interpreting  the  Disclosure  Documents  and  evaluating  the  merits  and 
risks of the prospective investment in the Securities and has the net worth to undertake such risks. 

2 

   
   
   
   
   
   
   
   
  
(d) 

(e) 

(f) 

(g) 

(h) 

(i) 

(j) 

(k) 

The undersigned has obtained, to the extent it deems necessary, professional advice with respect to the risks inherent in the investment 
in the Securities, and the suitability of the investment in the Securities in light of its financial condition and investment needs. 

The undersigned believes that the investment in the Securities is suitable for it based upon its investment objectives and financial needs, 
and the undersigned has adequate means for providing for its current financial needs and contingencies and has no need for liquidity of 
investment with respect to the Securities. 

The undersigned understands that no public market for the Securities exists, or is likely to develop, and that it may not be possible to 
liquidate this investment readily, if at all, in the case of an emergency or for any other reason. 

The undersigned recognizes that an investment in the Securities involves a high degree of risk. 

The  undersigned  realizes  that  (1)  the  purchase  of  the  Securities  and  the  shares  into  which  they  may  be  exchanged  is  a  long-term 
investment, (2) the purchaser of the Securities must bear the economic risk of investment for an indefinite period of time because the 
Securities and any such shares that may be issued upon exercise of the Warrant will not have been registered under the Securities Act of 
1933 and, therefore, cannot be sold unless they are subsequently registered under said Act or an exemption from such registration is 
available  and  (3)  the  transferability  of  the  Securities  and  such  shares  is  restricted  pending  effectiveness  of  such  a  registration  of 
qualification for an exemption. 

The undersigned has been advised that the offering and issuance of Securities and any exchange of the Securities will not be registered 
under the Securities Act of 1933 or the relevant state securities laws but are being offered and issued pursuant to exemptions from such 
laws  and  that  the  Company’s  reliance  upon  such  exemptions  is  predicated  in  part  on  the  undersigned’s  representations  as  contained 
herein.  The  undersigned  represents  and  warrants  that  the  Securities  are  being  purchased  for  the  undersigned’s  own  account  and  for 
investment and without the intention of reselling or redistributing the same, that it has made no agreement with others regarding any of 
such Securities and that its financial condition is such that it is not likely that it will be necessary to dispose of any of the Securities in 
the foreseeable future. 

The undersigned represents and warrants that it is a bona fide resident of, and is domiciled in the state indicated on the signature page 
below under “Address”, and that the Securities are being purchased by it in its name solely for its own beneficial interest and not as 
nominee for, or on behalf of, or for the beneficial interest of, or with the intention to transfer to, any other person, trust or organization. 

The  undersigned  understands  that  the  representations  contained  below  are  made  for  the  purpose  of  qualifying  it  is  an  “accredited 
investor” as that term is defined in Regulation D of the General Rules and Regulations under the Securities Act of 1933 and for the 
purpose of inducing a sale of securities to it. The undersigned hereby represents that the statement or statements initialled below are true 
and  correct  in  all  respects.  The  undersigned  understands  that  a  false  representation  may  constitute  a  violation  of  law,  and  that  any 
person who suffers damage as a result of a false representation may have a claim against the undersigned for damages. 

3 

   
   
   
   
   
   
   
   
   
  
(l) 

The undersigned understands that certificates evidencing the Securities may bear the following or any similar legend (in addition to any 
other legends that may be required): 

(i) “THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, 
OR  THE  SECURITIES  LAWS  OF  ANY  STATE  AND  MAY  NOT  BE  SOLD  OR  OFFERED  FOR  SALE  IN  THE 
ABSENCE  OF  AN  EFFECTIVE  REGISTRATION  STATEMENT  FOR  THE  SECURITIES  OR  AN  OPINION  OF 
COUNSEL  OR  OTHER  EVIDENCE  ACCEPTABLE  TO  THE  COMPANY  THAT  SUCH  REGISTRATION  IS  NOT 
REQUIRED.” 

(ii) If required by the authorities of any state in connection with the issuance of sale of the Securities, the legend required by 
such state authority. 

(m) 

(n) 

(o) 

The undersigned represents and warrants that it did not learn of the investment in the Securities as a result of any general solicitation or 
general advertising. 

Since the date on which undersigned first learned about the investment opportunity, the undersigned has not disclosed any information 
regarding  such  opportunity  to  any  third  parties  (other  than  its  affiliates  and  legal,  accounting  and  other  advisors  who  are  bound  by 
agreements  or  duties  of  confidentiality)  and  has  not  engaged  in  any  purchases  or  sales  involving  the  securities  of  the  Company 
(including, without limitation, any short sales involving the Company’s securities). The undersigned agrees that it will not engage in 
any  purchases  or  sales  involving  the  securities  of  the  Company  (including  short  sales)  prior  to  the  time  that  the  transactions 
contemplated  by  this  Agreement  are  publicly  disclosed.  The  undersigned  agrees  that  it  will  not  use  any  of  the  Securities  acquired 
pursuant  to  this  Subscription  Agreement  to  cover  any  short  position  in  the  Common  Stock  if  doing  so  would  be  in  violation  of 
applicable  securities  laws.  For  purposes  hereof,  “short  sales”  include,  without  limitation,  all  “short  sales”  as  defined  in  Rule 200 
promulgated  under  Regulation SHO  under  the  1934  Act,  whether  or  not  against  the  box,  and  all  types  of  direct  and  indirect  stock 
pledges, forward sales contracts, options, puts, calls, short sales, swaps, “put equivalent positions” (as defined in Rule 16a-1(h) under 
the  1934  Act)  and  similar  arrangements  (including  on  a  total  return  basis),  and  sales  and  other  transactions  through  non-US  broker 
dealers or foreign regulated brokers. 

The undersigned acknowledges that prior to acquiring the Securities, the undersigned has been provided with financial and other written 
information about the Company and the terms and conditions of the offering. The undersigned has been given the opportunity by the 
Company to obtain such information and ask such questions concerning the Company, the Securities and the undersigned’s investment 
as  the  undersigned  felt  necessary,  and  to  the  extent  the  undersigned  took  such  opportunity,  the  Purchaser  received  satisfactory 
information  and  answers.  If  the  undersigned  requested  any  additional  information  which  the  Company  possessed  or  could  acquire 
without  unreasonable  effort  or  expense  which  was  necessary  to  verify  the  accuracy  of  the  financial  and  other  written  information 
furnished to the undersigned by the Company, such additional information was provided to the undersigned and was satisfactory. 

4 

   
   
   
   
   
   
   
  
3. Accredited Investor Status . The undersigned is an “accredited investor” within the meaning of Regulation D promulgated under the Securities 
Act of 1933, as amended (the “ Act ”). The specific category or categories of “accredited investor” applicable to the undersigned are as follows:  

(a) 

Accredited individual investors must initial either or both of the following two statements: 

_____ (1) 

_____ (2) 

I certify that I am an accredited investor because I had individual income (exclusive of any income attributable to my spouse) of 
more than $200,000 in each of the most recent two years or joint income with my spouse of more than $300,000 in each of such 
years and I reasonably expect to have an individual income in excess of such amounts for the current year. 

I certify that I am an accredited investor because I have an individual net worth, or my spouse and I have a combined individual 
net worth, in excess of $1,000,000. For purposes of this questionnaire, “net worth” excludes the equity in my or our primary 
residence. 

(b) 

Accredited partnerships, corporations or other entities must initial one or more of the following statements, and must initial the last 
statement: 

_____ (1) 

The  undersigned  hereby  certifies  that  all  of  the  beneficial  equity  owners  of  the  undersigned  qualify  as  accredited  individual 
investors  under  items  (a)(1)  or  (a)(2)  above.  (Subscribers  attempting  to  qualify  under  this  item  may  be  required  to  provide 
additional information beyond the equity owner of the Subscriber) 

_____ (2) 

The undersigned is a bank or savings and loan association as defined in Sections 3(a)(2) and 3(a)(5)(A), respectively, of the Act 
acting either in its individual or fiduciary capacity. 

_____ (3) 

The undersigned is an insurance company as defined in Section 2(a)(13) of the Act. 

_____ (4) 

The  undersigned  is  an  investment  company  registered  under  the  Investment  Company  Act  of  1940  or  a  business  development 
company as defined in Section 2(a)(48) of that act. 

_____ (5) 

This Agreement has been duly authorized by all necessary action on the part of the undersigned, has been duly executed by an 
authorized officer or representative of the undersigned, and is a legal, valid and binding obligation of the undersigned enforceable 
in accordance with its terms. 

5 

   
   
   
   
   
    
  
  
  
  
  
  
  
  
  
  
  
Subscription Amount : $ ______________  

Number of Units : ______________  

Manner in which title to the Class A Convertible Preferred Stock and Warrants are to be held (please initial one):  

_____ Individual 
_____ Community Property 
_____ Corporation 
_____ IRA 
_____ SEP/SIMPLE 
_____ Partnership 

_____ Joint tenants with Right of Survivorship 
_____ Tenants-in-Common 
_____ Trust 
_____ Qualified Retirement Plans 
_____ LLC 
_____ Other 

IN WITNESS WHEREOF, the undersigned has executed 
this Subscription Agreement this ________ ___, 2014 

______________________________ 

______________________________ 

Name : ______________________________ 

Name : ______________________________ 

* * * * * * * *  

6 

   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
PLEASE PRINT BELOW THE REGISTRATION  
INFORMATION OF EACH SUBSCRIBER  

SUBSCRIBER (INDIVIDUAL and JOINT) 
(Please type or print name[s] exactly as it should appear on the 
Certificate) 

ENTITY 
(Please type or print name[s] exactly as it should appear on the 
Certificate) 

Name(s) Typed or Printed 

Name Typed or Printed 

Daytime Phone 

Email Address 

Business Phone 

Email Address 

Address to Which Correspondence Should be Directed: 

Address to Which Correspondence Should be Directed: 

Social Security Number 

Rep # 

Name Person to Contact 

Entity’s Taxpayer Identification Number 

(for use by Selling Agent) 

Subscription Approved by Principal 

__________________________ on ____/____/2014 

7 

   
   
   
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
Exhibit 10.35 

IMPORTANT: PLEASE READ CAREFULLY BEFORE SIGNING  
SIGNIFICANT REPRESENTATIONS ARE CALLED FOR HEREIN  

ELECTION TO CONVERT AND LETTER OF INVESTMENT INTENT  

The undersigned hereby tenders this Election to Convert and applies for the conversion of that portion (the “ Conversion Amount ”) of 
the principal and accrued interest outstanding under the Convertible Promissory Note(s) indicated on the signature page hereof (the “ Note ”) 
into Units, consisting of a share of Class A Convertible Preferred Stock and a Warrant for the purchase of Common Stock (“the Securities ”) of 
Cryoport, Inc. (the “ Company ”), pursuant to the terms of the Note and upon the terms and conditions set forth below.  

In  connection  with  the  conversion  of  the  Note,  the  undersigned  hereby  assigns,  transfers,  conveys,  surrenders,  and  releases  to  the 
Company  the  Conversion  Amount  of  the  Note.  Concurrently  with  delivery  of  this  Election  to  Convert,  the  undersigned  shall  deliver  to  the 
Company  the  original  Note  for  cancellation,  which  Note  will  be  cancelled  upon  Company’s  acceptance  of  this  Election  to  Convert.  If  the 
undersigned  elects  to  convert  less  than  the  entire  principal  and  accrued  interest  outstanding  under  the  Note,  then  the  Company  will  issue  a 
replacement  Note  for  the  remaining  amount;  provided,  that  such  replacement  Note  will  not  have  the  right  to  convert  into  the  Securities  in 
connection with this this offering.  

The  undersigned  understands  that  this  election  will  not  become  effective  unless  and  until  the  first  closing  of  the  offering  of  the 
Securities and that the Company will cause to be returned the Note delivered herewith if such closing does not occur. By execution below, the 
undersigned  acknowledges  that  the  Company  is  relying  upon  the  accuracy  and  completeness  of  the  representations  contained  herein  in 
complying with its obligations under applicable securities laws.  

1.  Conversion . 

(a) 

(b) 

Subject  to  the  terms  and  conditions  of  this  Election  to  Convert,  the  undersigned  hereby  irrevocably  elects  to  convert  the 
Conversion Amount of the Note for the Securities. The conversion price for one share of Class A Convertible Preferred Stock 
and a warrant to purchase eight shares of Common Stock at an exercise price of $0.50 per share (the “ Warrant ”) shall equal 
$10.80 (the “ Conversion Price ”). No fractional shares will be issued. If the conversion amount yields a fractional share of 0.5 
or more, the number of shares will be rounded up and all other fractional shares will be rounded down. 

The  Class  A  Convertible  Preferred  Stock  will  be  issued  pursuant  to  the  terms  and  conditions  set  forth  in  the  certificate  of 
designation  (“  Certificate  of  Designation  ”)  that  will  be  filed  with  the  Secretary  of  State  of  Nevada  on  or  before  the  first 
closing in connection with the offering of the Securities. 

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(c) 

THE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR THE SECURITIES 
LAWS  OF  ANY  STATE  OR  ANY  OTHER  JURISDICTION.  THERE  ARE  FURTHER  RESTRICTIONS  ON  THE 
TRANSFERABILITY  OF  THE  SECURITIES  DESCRIBED  HEREIN.  THE  ACQUISITION  OF  THE  SECURITIES 
INVOLVES  A  HIGH  DEGREE  OF  RISK  AND  SHOULD  BE  CONSIDERED  ONLY  BY  PERSONS  WHO  CAN  BEAR 
THE RISK OF THE LOSS OF THEIR ENTIRE INVESTMENT. 

2.  Representations . The undersigned acknowledges and represents as follows: 

(a) 

(b) 

(c) 

(d) 

(e) 

(f) 

The  undersigned  has  received,  and  is  familiar  with  the  Company’s  Private  Placement  Memorandum  dated  March  5,  2014,  the 
Certificate  of  Designation,  the  Warrant  Agreement  and  the  publicly  available  filings  by  the  Company  with  the  Securities  Exchange 
Commission (collectively the “ Disclosure Documents ”). 

The undersigned is in a financial position to hold the Securities for an indefinite period of time and is able to bear the economic risk and 
withstand a complete loss of its investment in the Securities. 

The  undersigned  believes  it,  either  alone  or  with  the  assistance  of  its  professional  advisor,  has  such  knowledge  and  experience  in 
financial and business matters that  it  is  capable  of  reading  and  interpreting  the  Disclosure  Documents  and  evaluating  the  merits  and 
risks of the prospective investment in the Securities and has the net worth to undertake such risks. 

The undersigned has obtained, to the extent it deems necessary, professional advice with respect to the risks inherent in the investment 
in the Securities, and the suitability of the investment in the Securities in light of its financial condition and investment needs. 

The undersigned believes that the investment in the Securities is suitable for it based upon its investment objectives and financial needs, 
and the undersigned has adequate means for providing for its current financial needs and contingencies and has no need for liquidity of 
investment with respect to the Securities. 

The undersigned understands that no public market for the Securities exists, or is likely to develop, and that it may not be possible to 
liquidate this investment readily, if at all, in the case of an emergency or for any other reason. 

(g) 

The undersigned recognizes that an investment in the Securities involves a high degree of risk. 

(h) 

The undersigned realizes that (1) the conversion of the Note for the Securities and the shares into which they may be exchanged is a 
long-term  investment,  (2)  the  undersigned  must  bear  the  economic  risk  of  investment  for  an  indefinite  period  of  time  because  the 
Securities and any such shares that may be issued upon exercise of the Warrant will not have been registered under the Securities Act of 
1933 and, therefore, cannot be sold unless they are subsequently registered under said Act or an exemption from such registration is 
available  and  (3)  the  transferability  of  the  Securities  and  such  shares  is  restricted  pending  effectiveness  of  such  a  registration  of 
qualification for an exemption. 

   
   
   
   
   
   
   
   
   
   
   
  
  
(i) 

(j) 

(k) 

The undersigned has been advised that the offering and issuance of Securities and any exchange of the Securities will not be registered 
under the Securities Act of 1933 or the relevant state securities laws but are being offered and issued pursuant to exemptions from such 
laws  and  that  the  Company’s  reliance  upon  such  exemptions  is  predicated  in  part  on  the  undersigned’s  representations  as  contained 
herein.  The  undersigned  represents  and  warrants  that  the  Securities  are  being  acquired  for  the  undersigned’s  own  account  and  for 
investment and without the intention of reselling or redistributing the same, that it has made no agreement with others regarding any of 
such Securities and that its financial condition is such that it is not likely that it will be necessary to dispose of any of the Securities in 
the foreseeable future. 

The undersigned represents and warrants that it is a bona fide resident of, and is domiciled in the state indicated on the signature page 
below  under  “Address”,  and  that  the  Securities  are  being  acquired  by  it  in  its  name  solely  for  its  own  beneficial  interest  and  not  as 
nominee for, or on behalf of, or for the beneficial interest of, or with the intention to transfer to, any other person, trust or organization. 

The  undersigned  understands  that  the  representations  contained  below  are  made  for  the  purpose  of  qualifying  it  is  an  “accredited 
investor” as that term is defined in Regulation D of the General Rules and Regulations under the Securities Act of 1933 and for the 
purpose of inducing a sale of securities to it. The undersigned hereby represents that the statement or statements initialled below are true 
and  correct  in  all  respects.  The  undersigned  understands  that  a  false  representation  may  constitute  a  violation  of  law,  and  that  any 
person who suffers damage as a result of a false representation may have a claim against the undersigned for damages. 

(l) 

The undersigned understands that certificates evidencing the Securities may bear the following or any similar legend (in addition to any 
other legends that may be required): 

(i) “THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, 
OR  THE  SECURITIES  LAWS  OF  ANY  STATE  AND  MAY  NOT  BE  SOLD  OR  OFFERED  FOR  SALE  IN  THE 
ABSENCE  OF  AN  EFFECTIVE  REGISTRATION  STATEMENT  FOR  THE  SECURITIES  OR  AN  OPINION  OF 
COUNSEL  OR  OTHER  EVIDENCE  ACCEPTABLE  TO  THE  COMPANY  THAT  SUCH  REGISTRATION  IS  NOT 
REQUIRED.” 

(ii) If required by the authorities of any state in connection with the issuance of sale of the Securities, the legend required by 
such state authority. 

(m) 

The undersigned represents and warrants that it did not learn of the investment in the Securities as a result of any general solicitation or 
general advertising. 

   
   
   
   
   
   
   
   
  
  
(n) 

(o) 

Since the date on which undersigned first learned about the investment opportunity, the undersigned has not disclosed any information 
regarding  such  opportunity  to  any  third  parties  (other  than  its  affiliates  and  legal,  accounting  and  other  advisors  who  are  bound  by 
agreements  or  duties  of  confidentiality)  and  has  not  engaged  in  any  purchases  or  sales  involving  the  securities  of  the  Company 
(including, without limitation, any short sales involving the Company’s securities). The undersigned agrees that it will not engage in 
any  purchases  or  sales  involving  the  securities  of  the  Company  (including  short  sales)  prior  to  the  time  that  the  transactions 
contemplated  by  this  Election  to  Convert  are  publicly  disclosed.  The  undersigned  agrees  that  it  will  not  use  any  of  the  Securities 
acquired pursuant  to  this Election to Convert to cover  any short position in the Common Stock if doing so  would be in violation of 
applicable  securities  laws.  For  purposes  hereof,  “short  sales”  include,  without  limitation,  all  “short  sales”  as  defined  in  Rule 200 
promulgated  under  Regulation SHO  under  the  1934  Act,  whether  or  not  against  the  box,  and  all  types  of  direct  and  indirect  stock 
pledges, forward sales contracts, options, puts, calls, short sales, swaps, “put equivalent positions” (as defined in Rule 16a-1(h) under 
the  1934  Act)  and  similar  arrangements  (including  on  a  total  return  basis),  and  sales  and  other  transactions  through  non-US  broker 
dealers or foreign regulated brokers. 

The undersigned acknowledges that prior to acquiring the Securities, the undersigned has been provided with financial and other written 
information about the Company and the terms and conditions of the offering. The undersigned has been given the opportunity by the 
Company to obtain such information and ask such questions concerning the Company, the Securities and the undersigned’s investment 
as  the  undersigned  felt  necessary,  and  to  the  extent  the  undersigned  took  such  opportunity,  the  undersigned  received  satisfactory 
information  and  answers.  If  the  undersigned  requested  any  additional  information  which  the  Company  possessed  or  could  acquire 
without  unreasonable  effort  or  expense  which  was  necessary  to  verify  the  accuracy  of  the  financial  and  other  written  information 
furnished to the undersigned by the Company, such additional information was provided to the undersigned and was satisfactory. 

3. Accredited Investor Status . The undersigned is an “accredited investor” within the meaning of Regulation D promulgated under the Securities 
Act of 1933, as amended (the “ Act ”). The specific category or categories of “accredited investor” applicable to the undersigned are as follows:  

(a) 

Accredited individual investors must initial either or both of the following two statements: 

_____ (1) 

_____ (2) 

I certify that I am an accredited investor because I had individual income (exclusive of any income attributable to my spouse) of 
more than $200,000 in each of the most recent two years or joint income with my spouse of more than $300,000 in each of such 
years and I reasonably expect to have an individual income in excess of such amounts for the current year. 

I certify that I am an accredited investor because I have an individual net worth, or my spouse and I have a combined individual 
net  worth,  in  excess  of  $1,000,000.  For  purposes  of  this  questionnaire,  “net  worth”  excludes  the  equity  in  my  or  our  primary 
residence. 

   
   
   
   
   
   
  
  
  
  
(b) 

Accredited partnerships, corporations or other entities must initial one or more of the following statements, and must initial the last 
statement: 

_____ (1) 

The  undersigned  hereby  certifies  that  all  of  the  beneficial  equity  owners  of  the  undersigned  qualify  as  accredited  individual 
investors under items (a)(1) or (a)(2) above. (Those attempting to qualify under this item may be required to provide additional 
information beyond the equity owner of the entity) 

_____ (2) 

The undersigned is a bank or savings and loan association as defined in Sections 3(a)(2) and 3(a)(5)(A), respectively, of the Act 
acting either in its individual or fiduciary capacity. 

_____ (3) 

The undersigned is an insurance company as defined in Section 2(a)(13) of the Act. 

_____ (4) 

The  undersigned  is  an  investment  company  registered  under  the  Investment  Company  Act  of  1940  or  a  business  development 
company as defined in Section 2(a)(48) of that act. 

_____ (5) 

The undersigned is a trust with total assets in excess of $5,000,000, not formed for the specific purpose of acquiring the Securities, 
and the undersigned is directed by a sophisticated person as described in Rule 506(b)(2)(ii) of the Act. 

_____ (6) 

The undersigned is a private business development company as defined in Section 202(a)(22) of the Investment Advisers Act of 
1940. 

_____ (7) 

This Election to Convert has been duly authorized by all necessary action on the part of the undersigned, has been duly executed 
by an authorized officer or representative of the undersigned, and is a legal, valid and binding obligation of the undersigned 
enforceable in accordance with its terms. 

   
   
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
Conversion Amount with respect to the following Convertible Promissory Note(s)  

Convertible Promissory Note dated as of _______________, 20__, with an original principal amount of $______________.  

Check one:  

_____ Elect to convert all principal and accrued interest currently outstanding  

_____ Elect to convert ___% of the principal and ___% of the accrued interest currently outstanding  

Convertible Promissory Note dated as of _______________, 20__, with an original principal amount of $______________.  

Check one:  

_____ Elect to convert all principal and accrued interest currently outstanding  

_____ Elect to convert ___% of the principal and ___% of the accrued interest currently outstanding  

Convertible Promissory Note dated as of _______________, 20__, with an original principal amount of $______________.  

Check one:  

_____ Elect to convert all principal and accrued interest currently outstanding  

_____ Elect to convert ___% of the principal and ___% of the accrued interest currently outstanding  

Manner in which title to the Class A Convertible Preferred Stock and Warrants are to be held (please initial one):  

_____ Individual 
_____ Community Property 
_____ Corporation 
_____ IRA 
_____ SEP/SIMPLE 
_____ Partnership 

_____ Joint tenants with Right of Survivorship 
_____ Tenants-in-Common 
_____ Trust 
_____ Qualified Retirement Plans 
_____ LLC 
_____ Other 

IN WITNESS WHEREOF, the undersigned has executed 
this Subscription Agreement this ________ ___, 2014 

______________________________ 

______________________________ 

Name : ______________________________ 

Name : ______________________________ 

* * * * * * * *  

6 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
PLEASE PRINT BELOW THE REGISTRATION  
INFORMATION OF EACH INDIVIDUAL OR ENTITY ELECTING TO CONVERT  

INDIVIDUAL and JOINT 
(Please type or print name[s] exactly as it should appear on the 
Certificate) 

ENTITY 
(Please type or print name[s] exactly as it should appear on the 
Certificate) 

Name(s) Typed or Printed 

Name Typed or Printed 

Daytime Phone 

Email Address 

Business Phone 

Email Address 

Address to Which Correspondence Should be Directed: 

Address to Which Correspondence Should be Directed: 

Social Security Number 

Rep # 

Name Person to Contact 

Entity’s Taxpayer Identification Number 

(for use by Selling Agent) 

Conversion Approved by Principal 

__________________________ on ____/____/2014 

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CryoPort Systems, Inc.  

CRYOPORT, INC.  
Subsidiaries of Registrant  

Exhibit 21 

   
   
   
   
  
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM  

We  consent  to  the  incorporation  by  reference  in  the  Registration  Statement  No.  333-166327  on  Form  S-8  of  our  report  dated  June  25,  2014 
(which  includes an explanatory paragraph  regarding  Cryoport, Inc.’s  ability to  continue as  a going  concern),  with respect  to  the consolidated 
financial statements of Cryoport, Inc. included in this Annual Report on Form 10-K of Cryoport, Inc. for the years ended March 31, 2014 and 
2013.  

Exhibit 23.1 

/s/ KMJ Corbin & Company LLP  

Costa Mesa, California  
June 25, 2014  

   
    
   
   
   
   
   
   
   
   
  
EXHIBIT 31.1 

I, Jerrell W. Shelton, certify that:  

CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER  

1. 

I have reviewed this Annual Report on Form 10-K of Cryoport, Inc.; 

2.  Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to 
make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period 
covered by this report; 

3.  Based  on  my  knowledge,  the  financial  statements,  and  other  financial  information  included  in  this  report,  fairly  present  in  all  material 
respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report; 

4.  The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined 
in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) 
and 15d-15(f)) for the registrant and have: 

a)  Designed  such  disclosure  controls  and  procedures,  or  caused  such  disclosure  controls  and  procedures  to  be  designed  under  our 
supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by 
others within those entities, particularly during the period in which this report is being prepared; 

b)  Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our 
supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements 
for external purposes in accordance with generally accepted accounting principles; 

c)  Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the 

effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and 

d)  Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most 
recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably 
likely to materially affect, the registrant’s internal control over financial reporting; and 

5.  The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, 
to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions): 

a)  All  significant deficiencies  and  material weaknesses in  the  design or  operation of internal control  over financial reporting which  are 

reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and 

b)  Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal 

control over financial reporting. 

Date: June 25, 2014  

/s/ JERRELL W. SHELTON 
JERRELL W. SHELTON  
Chief Executive Officer and Director  
(Principal Executive Officer)  

  
   
   
       
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
   
  
I, Robert S. Stefanovich, certify that:  

CERTIFICATION OF PRINCIPAL FINANCIAL OFFICER  

1. 

I have reviewed this Annual Report on Form 10-K of Cryoport, Inc.; 

EXHIBIT 31.2 

2.  Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to 
make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period 
covered by this report; 

3.  Based  on  my  knowledge,  the  financial  statements,  and  other  financial  information  included  in  this  report,  fairly  present  in  all  material 
respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report; 

4.  The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined 
in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) 
and 15d-15(f)) for the registrant and have: 

a)  Designed  such  disclosure  controls  and  procedures,  or  caused  such  disclosure  controls  and  procedures  to  be  designed  under  our 
supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by 
others within those entities, particularly during the period in which this report is being prepared; 

b)  Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our 
supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements 
for external purposes in accordance with generally accepted accounting principles; 

c)  Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the 

effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and 

d)  Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most 
recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably 
likely to materially affect, the registrant’s internal control over financial reporting; and 

5.  The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, 
to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions): 

a)  All  significant deficiencies  and  material weaknesses in  the  design or  operation of internal control  over financial reporting which  are 

reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and 

b)  Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal 

control over financial reporting. 

Date: June 25, 2014  

/s/ ROBERT S. STEFANOVICH 
Robert S. Stefanovich  
Chief Financial Officer  
(Principal Financial Officer)  

  
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER  

EXHIBIT 32.1 

Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, the undersigned officer of Cryoport, 
Inc. (the “Company”), hereby certifies, to such officer’s knowledge, that:  

(i) the accompanying Annual Report on Form 10-K of the Company for the year ended March 31, 2014 (the “Report”) fully complies with 

the requirements of Section 13(a) or Section 15(d), as applicable, of the Securities Exchange Act of 1934, as amended; and  

(ii) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the 

Company.  
Dated: June 25, 2014  

This certification accompanies this Report pursuant to Rule 13a-14(b) or Rule 15d-14(b) under the Securities Exchange Act of 1934, as 

amended, and 18 U.S.C. Section 1350 and shall not be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act 
of 1934, as amended.  

/s/ JERRELL W. SHELTON 
Jerrell W. Shelton  
Chief Executive Officer and Director  

   
   
   
   
   
   
   
   
  
  
  
  
CERTIFICATION OF PRINCIPAL FINANCIAL OFFICER  

EXHIBIT 32.2 

Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, the undersigned officer of Cryoport, 
Inc. (the “Company”), hereby certifies, to such officer’s knowledge, that:  

(i) the accompanying Annual Report on Form 10-K of the Company for the year ended March 31, 2014 (the “Report”) fully complies with 

the requirements of Section 13(a) or Section 15(d), as applicable, of the Securities Exchange Act of 1934, as amended; and  

(ii) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the 

Company.  
Dated: June 25, 2014  

This certification accompanies this Report pursuant to Rule 13a-14(b) or Rule 15d-14(b) under the Securities Exchange Act of 1934, as 

amended, and 18 U.S.C. Section 1350 and shall not be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act 
of 1934, as amended.  

/s/ ROBERT S. STEFANOVICH 
Robert S. Stefanovich  
Chief Financial Officer