Quarterlytics / Industrials / Integrated Freight & Logistics / Cryoport, Inc.

Cryoport, Inc.

cyrx · NASDAQ Industrials
Claim this profile
Ticker cyrx
Exchange NASDAQ
Sector Industrials
Industry Integrated Freight & Logistics
Employees 1090
← All annual reports
FY2015 Annual Report · Cryoport, Inc.
Sign in to download
Loading PDF…
UNITED STATES  
SECURITIES AND EXCHANGE COMMISSION  
Washington, D.C. 20549  

Form 10-K  

  ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT  

OF 1934 

For the fiscal year ended March 31, 2015  

(cid:1)  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 

Commission File Number: 001-34632  

CRYOPORT, INC.  
(Exact Name of Registrant as Specified in its Charter)  

Nevada 
(State or other jurisdiction of  
incorporation or organization)  

88-0313393 
(I.R.S. Employer  
Identification No.)  

20382 Barents Sea Circle  
Lake Forest, CA 92630  
(Address of principal executive offices)  

(949) 470-2300  
(Registrant’s telephone number, including area code)  

Securities registered pursuant to Section 12(b) of the Act:  

Title of Each Class 
Common Stock, $0.001 par value 

  Name of Each Exchange on Which Registered   
OTC Market 

Securities registered pursuant to Section 12(g) of the Act:  
Common Stock, $0.001  
Warrants to Purchase Common Stock  

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act.    Yes   (cid:1)     No     

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act.   Yes   (cid:1)     No     

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act 
of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject 
to such filing requirements for the past 90 days.    Yes        No   (cid:1)  

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data 
File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§ 229.405 of this chapter) during the preceding 12 months (or 
for such shorter period that the registrant was required to submit and post such files).    Yes        No   (cid:1)  

Indicate  by  check  mark  if  disclosure  of  delinquent  filers  pursuant  to  Item 405  of  Regulation S-K  is  not  contained  herein,  and  will  not  be 
contained,  to  the  best  of  registrant’s  knowledge,  in  definitive  proxy  or  information  statements  incorporated  by  reference  in  Part III  of  this 
Form 10-K or any amendment to this Form 10-K    (cid:1)  

Indicate  by  check  mark  whether  the  registrant  is  a  large  accelerated  filer,  an  accelerated  filer,  a  non-accelerated  filer,  or  a  smaller  reporting 
company. See the definitions of “large  accelerated filer,” “accelerated filer” and “smaller reporting company” in  Rule 12b-2 of the Exchange 

   
   
   
   
   
   
   
   
   
    
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
Act. (Check one):  

Large accelerated filer  (cid:1) 

Non-accelerated filer  (cid:1)   (Do not check if a smaller reporting company) 

Accelerated filer 

(cid:1) 

Smaller reporting company   

Indicate by check mark whether the Registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).    Yes   (cid:1)     No     

The aggregate market value of Common Stock held by non-affiliates of the registrant as of September 30, 2014 was $25,056,500(1) based on the 
closing sale price of such common equity on such date.  

As of May 8, 2015 there were 5,025,577 shares of the registrant’s common stock outstanding.  

(1) Excludes 215,286 shares of common stock held by directors and officers, and any stockholders whose ownership exceeds five percent of the 
shares outstanding as of September 30, 2014.  

DOCUMENTS INCORPORATED BY REFERENCE  

   
   
   
   
   
   
   
   
  
  
  
  
  
  
Item 1. 
Item 1A. 
Item 1B. 
Item 2. 
Item 3. 
Item 4. 

Item 5. 
Item 6. 
Item 7. 
Item 7A. 
Item 8. 
Item 9. 
Item 9A. 
Item 9B. 

Item 10. 
Item 11. 
Item 12. 
Item 13. 
Item 14. 

Item 15. 
Signatures 

TABLE OF CONTENTS  

PART I 

Business 
Risk Factors 
Unresolved Staff Comments 
Properties 
Legal Proceedings 
Mine Safety Disclosures 

PART II 
Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities 
Selected Financial Data 
Management’s Discussion and Analysis of Financial Condition and Results of Operations 
Quantitative and Qualitative Disclosures About Market Risk 
Financial Statements and Supplementary Data 
Changes in and Disagreements with Accountants on Accounting and Financial Disclosure 
Controls and Procedures 
Other Information 

Directors, Executive Officers and Corporate Governance 
Executive Compensation 
Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters 
Certain Relationships and Related Transactions, and Director Independence 
Principal Accountant Fees and Services 

PART III 

Exhibits and Financial Statement Schedules 

PART IV 

2 

Page 

3 
18 
30 
30 
31 
31 

31 
32 
33 
40 
40 
40 
40 
41 

43 
43 
48 
51 
52 

53 
59 

   
   
   
  
  
  
FORWARD-LOOKING STATEMENTS  

Unless  the  context  otherwise  requires,  all  references  in  this  Annual  Report  on  Form 10-K  to  the  “Company”,  “we,”  “us,”  “our,”  or 
“Cryoport” refer to Cryoport, Inc. and our wholly owned subsidiary, Cryoport Systems, Inc. In addition, we own or have rights to the registered 
trademark Cryoport  ® (both alone and with a design  logo) and Cryoport Express  ® (both alone and with  a design logo). All other Company 
names,  registered  trademarks,  trademarks,  and  service  marks  included  in  this  Annual  Report  are  trademarks,  registered  trademarks,  service 
marks, or trade names of their respective owners.  

Cryoport, Inc.’s Annual Report on Form 10-K contains certain forward-looking statements. These forward-looking statements involve a 
number of risks and uncertainties. These forward-looking statements can generally be identified as such because the context of the statement will 
include  certain  words,  including  but  not  limited  to,  “believes,”  “may,”  “will,”  “expects,”  “intends,”  “estimates,”  “anticipates,”  “plans,”
“seeks,” “continues,” “predicts,” “potential,” “likely,” or “opportunity,” and also contains predictions, estimates and other forward-looking 
statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, 
as  amended,  and  in  reliance  upon  the  safe  harbor  provisions  of  the  Private  Securities  Litigation  Reform  Act  of  1995.  Such  forward-looking 
statements are based on the current beliefs of the Company’s management, as well as assumptions made by and information currently available 
to  the  Company’s  management.  Readers  of  this  Annual  Report  on  Form 10-K  should  not  put  undue  reliance  on  these  forward-looking 
statements,  which  speak  only  as  of  the  time  this  Annual  Report  on  Form 10-K  was  filed  with  the  Securities  and  Exchange  Commission  (the 
“SEC”). Reference is made in particular to forward-looking statements regarding the success of our products, product approvals, product sales, 
revenues,  development  timelines, product  acquisitions,  liquidity  and  capital  resources  and  trends.  Forward-looking  statements  are  inherently 
subject to risks and uncertainties, some of which cannot be predicted or quantified. Cryoport Inc.’s actual results may differ materially from the 
results projected in the forward-looking statements. Factors that might cause such a difference include, but are not limited to, those discussed in 
this Annual Report on Form 10-K, including the “Risk Factors” in “Item 1A — Risk Factors”, and in “Item 7 — Management’s Discussion and 
Analysis  of  Financial  Condition  and  Results  of  Operations”  included  in  Part II.  In  addition,  past  financial  or  operating  performance  is  not 
necessarily a reliable indicator of future performance, and you should not use our historical performance to anticipate results or future period 
trends. We can give no assurances that any of the events anticipated by the forward-looking statements will occur or, if any of them do, what 
impact they will have on our results of operations and financial condition. Except as required by law, we do not undertake to update any such 
forward-looking statements and expressly disclaim any duty to update the information contained in this Annual Report on Form 10-K.  

PART 1  

Item 1.  Business  

Overview  

Cryoport is a leading provider of cryogenic logistics solutions to the life sciences industry through its purpose-built proprietary packaging, 
information technology and specialized cold chain logistics expertise. We provide leading edge logistics solutions for biologic materials such as 
immunotherapies, stem cells, CAR-T cells, and reproductive cells for clients worldwide, including points-of-care, CRO’s, central laboratories, 
biopharmaceuticals,  contract  manufacturing,  health  centers  and  university  research.  Our  packaging  is  built  around  our  proprietary  Cryoport 
Express  ® liquid nitrogen dry vapor shippers, which are validated to maintain a constant -150°C temperature for a ten day dynamic shipment 
duration. Our information technology centers on our Cryoportal™ Logistics Management Platform, which facilitates management of the entire 
shipment process.  

We view our solutions as disruptive to “older technologies” such as dry ice, in that our solutions provide reliable, economic alternatives to 
existing solutions and services utilized for frozen shipping in life sciences, including immunotherapies, stem cells, cell lines, vaccines, diagnostic 
materials,  semen,  eggs,  embryos,  cord  blood,  bio-pharmaceuticals,  infectious  substances  and  other  items  that  require  continuous  exposure  to 
frozen or cryogenic temperatures.  

Our Cryoport Express ® Solutions include a sophisticated cloud-based logistics operating platform, which is branded as the Cryoportal™. 
The Cryoportal™ supports the management of the entire shipment and logistics process through a single interface, including initial order input, 
document preparation, customs clearance, courier management, shipment tracking, issue resolution, and delivery. In addition, it provides unique 
and incisive information dashboards and validation documentation for every shipment. The Cryoportal™ records and retains a fully documented 
“chain-of-custody” and, at the client’s option, “chain-of-condition” for every shipment, helping ensure that quality, safety, efficacy, and stability 
of  shipped  commodities  are  maintained  throughout  the  process.  This  recorded  and  archived  information  allows  our  clients  to  meet  exacting 
requirements necessary for scientific work and for proof of regulatory compliance during the logistics phase.  

3 

   
   
   
   
   
   
   
   
   
   
  
The  branded  packaging  for  our  Cryoport  Express  ®  Solutions  includes  our  liquid  nitrogen  dry  vapor  shippers,  the  Cryoport  Express  ® 
Shippers.  The  Cryoport  Express  ®  Shippers  are  cost-effective  and  reusable  cryogenic  transport  containers  (our  standard  shipper  is  a  patented 
vacuum  flask)  utilizing  an  innovative  application  of  “dry  vapor”  liquid  nitrogen  (“LN2”)  technology.  Cryoport  Express  ®  Shippers  are 
International Air Transport Association (“IATA”) certified and validated to maintain stable temperatures of minus 150° C and below for a 10-
day dynamic shipment period. The Company currently features three Cryoport Express ® Shippers: the Standard Dry Shipper (holding up to 75 
2.0 ml vials), the High Volume Dry Shipper (holding up to 500 2.0 ml vials) and the recently introduced Cryoport Express ® CXVC1 Shipper 
(holding up to 1,500 2.0 ml vials). In addition, we assist clients with internal secondary packaging as well (e.g., vials, canes, straws, plates, etc.)  

Our most used solution is the “turnkey” solution, which can be accessed directly through our cloud-based Cryoportal™ or by contacting 
Cryoport Client Care for order entry. Once an order is placed and cleared, we ship a fully charged Cryoport Express ® Shipper to the client who 
conveniently  loads  its  frozen  commodity  into  the  inner  chamber  of  the  Cryoport  Express  ®  Shipper  .  The  customer  then  closes  the  shipper 
package and reseals the shipping box displaying the next recipient’s address (“Flap A”) for pre-arranged carrier pick up. Cryoport arranges for 
the pick-up of the parcel by a shipping service provider, which is designated by the client or chosen by Cryoport, for delivery to the client’s 
intended recipient. The recipient simply opens the shipper package and removes the frozen commodity that has been shipped. The recipient then 
reseals  the  package,  displaying  the  nearest  Cryoport  Operations  Center  address  (“Flap  B”),  making  it  ready  for  pre-arranged  carrier  pick-up. 
When the Cryoport Operations Center receives the Cryoport Express ® Shipper, it is cleaned, put through quality assurance testing, and returned 
to inventory for reuse.  

In late 2012, we shifted our focus to become a comprehensive cryogenic logistics solutions provider. Recognizing that clients in the life 
sciences  industry  have  varying  requirements,  we  unbundled  our  technologies,  established  customer  facing  solutions  and  took  a  consultative 
approach to the market. Today, in addition to our standard “Turn-key Solution,” described above, we also provide the following customer facing, 
value-added solutions to address our various clients’ needs:  

• 

• 

• 

• 

• 

• 

“ Customer Staged Solution ,” designed for clients making 50 or more shipments per month. Under this solution, we supply an inventory of 
our Cryoport Express ® Shippers to our customer, in an uncharged state, enabling our customer (after training/certification) to charge them 
with  liquid  nitrogen  and  use  our  Cryoportal™  to  enter  orders  with  shipping  and  delivery  service  providers  for  the  transportation  of  the 
package. 

“ Customer Managed Solution ,” a limited customer implemented solution, whereby we supply our Cryoport Express ® Shippers to clients 
in  a  fully  charged  state,  but  leaving  it  to  the  client  to  manage  the  shipping,  including  the  selection  of  the  shipping  and  delivery  service 
provider and the return of the shipper to us. 

“  powered  by  Cryoport  SM  ,”  available  to  providers  of  shipping  and  delivery  services  who  seek  to  offer  a  “branded”  cryogenic  logistics 
solution as part of their service offerings, with “ powered by Cryoport  SM ” appearing prominently on the offering software interface and 
packaging. This solution can also be private labeled upon meeting certain requirements, such as minimum required shipping volumes. 

“ Integrated Solution, ” which is our total outsource solution. It is our most comprehensive solution and involves our management of the 
entire cryogenic logistics process for our client, including Cryoport employees at the client’s site to manage the client’s cryogenic logistics 
function in total. 

“ Regenerative Medicine Point-of-Care Repository Solution, ” designed for allogeneic therapies. In this solution we supply our Cryoport 
Express ® Shipper to ship and store cryogenically preserved life science products for up to six days (or longer periods with supplementary 
shippers) at a point-of-care site, with the Cryoport Express  ® Shipper serving as a temporary freezer/repository enabling the efficient and 
effective  distribution  of  temperature  sensitive  allogeneic  cell-based  therapies  without  the  expense,  inconvenience,  and  potential  costly 
failure of an on-sight, cryopreservation device. 

“  Personalized  Medicine  and  Cell-based  Immunotherapy  Solution,  ”  designed  for  autologous  therapies.  In  this  solution  our  Cryoport 
Express ® Shipper serves as an enabling technology for the safe transportation of manufactured autologous cellular-based immunotherapy 
market by providing a comprehensive logistics solution for the verified chain of custody and condition transport from, (a) the collection of 
the patient’s cells in a hospital setting, to (b) a central processing facility where they are manufactured into a personalized medicine, to (c) 
the safe, cryogenically preserved return of these irreplaceable cells to a point-of-care treatment facility.  If required, the Cryoport Express ® 
Shipper can then serve as a temporary freezer/repository to allow the efficient distribution of this personalized medicine to the patient when 
and  where  the  medical  provider  needs  it  most  without  the  expense,  inconvenience,  and  potential  costly  failure  of  an  on-sight, 
cryopreservation device. 

4 

   
   
   
   
   
   
   
   
   
   
  
Competitive Advantages  

With  our  first-to-market  cryogenic  logistics  solutions  for  the  life  sciences  industry,  we  have  established  a  unique  lead  over  potential 
competitors. Furthermore, we are not aware of a company that offers comparable solutions and has the same capabilities Cryoport has as a global 
provider  of  advanced,  validated  cryogenic  logistics  solutions.  As  a  solutions  company  working  with  our  tools  in  packaging,  information 
technology, and cryogenic logistics, we address our growing $1.7 billion cryogenic logistics market in innovative and creative ways.  

The majority of our competition utilizes “old technologies.” In fact, most of our market still uses dry ice and liquid nitrogen. In the case of 
dry ice the technology does not deliver cryogenic temperatures and, consequently, this medium allows cells to degrade, sometimes beyond any 
utility. When biology was less developed, dry ice was believed to be acceptable and was readily available.  

Liquid  nitrogen, on the  other hand,  while  effective, is  bulky,  expensive  and  has special handling requirements.  Both  dry ice  and  liquid 
nitrogen  are  classified  “hazardous”  by  shipping  companies  and  regulatory  authorities.  In  addition  to  being  ineffective  and/or  classified  as 
“dangerous goods,” they are inefficient when compared to Cryoport solutions. Conversely, Cryoport’s solutions are classified as non-hazardous.  

Having been validated and qualified as a solutions provider for hundreds of life sciences companies and institutions, Cryoport has logged 
over 20,000 shipments to over 80 countries with hundreds of life sciences materials. Once life sciences companies start utilizing our advance 
cryogenic logistics solutions, we experience minimal client attrition.  

While  we  look  at  companies  such  as  Thermo  Fisher  Scientific,  AmerisourceBergen  Corporation  and  Marken  as  potential  competitors, 

some of these companies are also our customers.  

We think our competitive position is further enhanced by our respective “powered by Cryoport” partnership agreements with FedEx, DHL 
and UPS, who collectively, account for approximately 85% of world’s air freight and who, individually, have been expanding their offerings of 
cold chain logistics solutions to the life sciences industry. In short, we are the cryogenic solution for each of them, employing our packaging, our 
software and our logistics expertise.  

The challenge for our seasoned, professional management team is to maintain what we believe to be a four year lead in the marketplace. In 
other  words,  we  think  it  would  take  a  serious  potential  competitor  at  least  four  years  to  build  out  the  competencies  that  we  possess  and  the 
knowledge we have of the marketplace.  

In  addition  to  our  intellectual  property  consisting  of  three  issued  U.S.  patents,  one  pending  U.S.  patent  application,  and  one  U.S. 
provisional patent application and our lead as the first to market mover, we think our biggest competitive advantage is our speed to market with 
new solutions and our sensitivity to anticipate and react to market needs. Our solutions are comprehensive and it is in our “DNA” to maintain 
our market lead by employing the best people in the industry as well as our current and new technologies to maintain that lead.  

Given  today’s  environmental  concerns,  we  also  consider  the  fact  that  we  are  “green”  to  be  a  competitive  advantage.  Our  packaging 
materials are recyclable and the key components are reusable. The fact that the inner and outer shells of our shippers are made of aircraft-grade 
aluminum makes these components recyclable as well. We take our responsibility toward the environment seriously.  

Strategic Logistics Alliances  

We have sought to establish strategic alliances as a method of marketing our solutions to the life sciences industry. We have focused our 
efforts  on  leading  companies  in  the  logistics  services  industry  as  well  as  participants  in  the  life  sciences  industry.  In  connection  with  our 
alliances with providers of shipping services, we refer to their offerings as “ powered by Cryoport SM ” to reflect our solutions being integrated 
into our alliance partner’s services.  

Cryoport  now  serves  and  supports  the  three  largest  integrators  in  the  world,  responsible  for  over 85%  of worldwide  airfreight,  with  its 
advanced cryogenic logistics solutions for life sciences. We operate  with each independently and confidentially in support  of  their  respective 
market  and  sales  strategies.  We  maintain  our  independent  partnerships  with  strict  confidentiality  guidelines  within  the  Company.  These 
agreements represent a significant validation of our solutions and the way we conduct our business.  

FedEx.  In  January  2013,  we  entered  into  a  master  agreement  with  Federal  Express  Corporation  (“FedEx”)  (the  “FedEx  Agreement”) 
renewing these services and providing FedEx with a non-exclusive license and right to use a customized version of our Cryoportal  TM for the 
management of shipments made by FedEx customers. Under our FedEx Agreement, we provide frozen shipping logistics services through the 
combination of our purpose-built proprietary technologies and turnkey management processes. FedEx markets and sells Cryoport’s services for 
frozen temperature-controlled cold chain transportation as its FedEx ® Deep Frozen Shipping Solution on a non-exclusive basis and at its sole 
expense. During fiscal year 2013, the Company worked closely with FedEx to further align its sales efforts and accelerate penetration within 
FedEx’s life sciences customer base through improved processes, sales incentives, joint customer calls and more frequent communication at the 
sales and executive level. In addition, FedEx has developed a FedEx branded version of the Cryoportal TM software platform, which is “ powered 
by Cryoport SM ” for use by its customers, giving them access to the full capabilities of our cloud-based logistics management software platform.  

5 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
DHL.  In  June  2014,  we  entered  into  a  master  agreement  with  LifeConEx,  a  part  of  DHL  Global  Forwarding  (“DHL”).  DHL  has  now 
enhanced  its  cold  chain  logistics  offerings  to  its  life  sciences  and  healthcare  customers  with  Cryoport’s  validated  cryogenic  solutions.  DHL 
added 15 additional certified Life Sciences stations in the second quarter of 2014 bringing its Thermonet network to 60 stations in operation. 
This  expanded  network  offers  Cryoport’s  cryogenic  solutions  under  the  DHL  brands  as  “  powered  by  Cryoport  SM  ”.  In  addition,  DHL’s 
customers  have  direct  access  to  our  cloud-based  order  entry  and  tracking  portal  to  order  Cryoport  Express  ®  Solutions  and  receive  preferred 
DHL  shipping  rates  and  discounts.  Our  proprietary  logistics  management  operating  platform,  the  Cryoportal  TM  ,  is  integrated  with  DHL’s 
tracking  and  billing  systems  to  provide  DHL  life  sciences  and  healthcare  customers  with  a  seamless  way  of  accessing  critical  information 
regarding shipments of biological material worldwide.  

UPS. In October 2014, we added United Parcel Services, Inc. (“UPS”) as our third major distributor by entering into an agreement with 
UPS Oasis Supply Corporation, a part of UPS, whereby UPS will offer our validated and comprehensive cryogenic solutions to its life sciences 
and healthcare customers on a global basis. Over the course of rolling out our new relationship with UPS, UPS customers will have direct access 
to our cloud-based order entry and tracking portal to order Cryoport Express ® Solutions and gain access to UPS’s broad array of domestic and 
international shipping and logistics solutions at competitive prices. Our proprietary logistics management operating platform, the Cryoportal TM , 
is integrated with UPS’s tracking and billing systems to provide UPS life sciences and healthcare customers with a seamless way of accessing 
critical information regarding shipments of biological material worldwide.  

These  agreements  with  the  three  largest  integrators  in  the  world,  controlling  more  than  85%  of  the  world’s  air  shipments,  represent  a 

significant validation of our solutions and the way we conduct our business.  

Cryoport’s Positioning in the Life Sciences Industry  

Life sciences technologies are expected to have a significant impact on global society over the next 25 years. In the United States alone, 
the life sciences industry is made up of 6,000 identifiable establishments. However, the industry is growing globally in a way where research and 
manufacturing pipelines span across the globe, which increases the need to mitigate logistics risk.  

The total cold chain logistics market has historically grown 70% faster per annum than the total logistics market. For 2011, global cold 
chain  logistics  transportation  costs  were  reported  to  be  $7.2  billion;  about  $1.5  billion  within  the  cryogenic  range  of  requirements.  By  2017, 
transportation cost alone, for global life sciences cold chain logistics, is forecasted to grow to $9.3 billion, a 41% increase, and twice the growth 
of the overall market.  

In  addition,  with  the  recent  advancements  in  the  development  of  biologics  and  cell-based  therapies,  scientists,  intermediaries,  and 
manufacturers require the means for cryogenically transporting their work. Temperatures must be maintained below the “glass point” (generally, 
minus  136ºC)  while  shipping  these  therapies  to  ensure  that  the  shipped  specimens  are  not  subject  to  degradation  that  could  impact  the 
characteristics and efficacy of those specimens.  

While we estimate that our solutions currently offer comprehensive and technology-based monitoring and tracking for a potential of six to 
seven  million  deep  frozen  shipments  globally  on  an  annual  basis,  we  also  believe  that  with  investment  in  our  services,  adaptations  of  our 
solutions can be applied to a large portion of an additional fifty-five to sixty million annual shipments requiring ambient (between 20° and 25°
C), chilled (between 2° and 8°C) or frozen (minus 10°C or less) temperatures.  

Cryoport’s  clients  include  companies  and  institutions  that  require  reliable  cryogenic  logistics  solutions  such  as  therapy  developers  for 
personalized  medicine,  bio-pharmaceuticals,  research,  contract  research  organizations,  diagnostic  laboratories,  contract  manufacturers,  cord 
blood repositories, vaccine manufacturers, animal husbandry related companies, and in-vitro fertilization clinics.  

Life Sciences Agreements  

Zoetis. In December 2012, we  signed an agreement with Pfizer  Inc. relating to  Zoetis Inc. (formerly the animal health  business unit of 
Pfizer  Inc.)  pursuant  to  which  we  were  engaged  to  manage  frozen  shipments  of  a  key  poultry  vaccine.  Under  this  arrangement,  Cryoport 
provides on-site logistics personnel and its logistics management operating platform, the Cryoportal  TM to manage shipments from the Zoetis 
manufacturing  site  in  the  United  States  to  domestic  customers  as  well  as  various  international  distribution  centers.  As  part  of  our  logistics 
management services, Cryoport is constantly analyzing logistics data and processes to further introduce economies and reliability throughout the 
network,  ensuring  products  arrive  at  their  destinations  in  specified  conditions,  on-time  and  with  the  optimum  utilization  of  resources.  The 
Company  manages  Zoetis’  total  fleet  of  dewar  flask  shippers  used  for  this  purpose,  including  liquid  nitrogen  shippers.  In  July  2013  the 
agreement  was  amended  to expand  Cryoport’s scope  to  manage  all logistics  of  Zoetis’ key  frozen poultry  vaccine  to  all  Zoetis’ international 
distribution centers as well as all domestic shipments. In October 2013, the agreement was further amended to further expand Cryoport’s role to 
include the logistics management for a second poultry vaccine.  

6 

   
   
   
   
   
   
   
   
   
   
   
   
  
Liventa Biosciences. In February 2014, we entered into a services agreement with Liventa Bioscience, Inc. (“Liventa”), a privately-held, 
commercial early stage biotechnology company focused on cell-based biologics in the orthopedic industry. Under this agreement, Liventa will 
use  Cryoport’s  Regenerative  Medicine  Point-of-Care  Repository  Solution  for  the  logistics  of  its  cell-based  therapies  requiring  cryogenic 
temperatures and also provide Cryoport Express ® Solutions to other biologics suppliers within the orthopedic arena. The agreement combines 
Cryoport’s proprietary, purpose-built cold chain logistics solutions for cell-based and advanced biologic tissue forms with Liventa’s distribution 
capability  to  orthopedic  care  providers.  The  implementation  of  Cryoport’s  Regenerative  Medicine  Point-of-Care  Repository  Solution  will 
eliminate  the  risks  of  degradation  and  also  eliminate  the  need  for  expensive  onsite  cryogenic  freezers  for  storage  of  cell-based  orthopedic 
therapies. The agreement has an initial three-year term and may be renewed for consecutive three-year terms, unless earlier terminated by either 
party. Liventa also agreed to certain performance criteria and the issuance of 150,000 shares of its common stock to Cryoport in exchange for the 
opportunity for an exclusive right to offer, market and promote Cryoport Express  ® Solutions for cellular-based therapies requiring cryogenic 
temperatures for use in the orthopedic arena in the United States.  

Corporate History and Structure  

The  Company  was  originally  incorporated  under  the  name  G.T.5-Limited  (“GT5”)  on  May  25,  1990  as  a  Nevada  Corporation.  Upon 
completion of a Share Exchange Agreement, on March 15, 2005 the Company changed its name to Cryoport, Inc. and acquired all of the issued 
and  outstanding  shares  of  Cryoport  Systems,  Inc.  Cryoport  Systems,  Inc.  remains  the  operating  company  under  Cryoport,  Inc.  At  that  time 
Cryoport  Systems,  Inc.  was  focused  on  developing  the  Cryoport  Express  ®  Shipper.  Over  time  the  Company  has  transitioned  from  being  a 
development company to providing global cold chain logistics solutions to the biotechnology and life sciences industries.  

Since 2011, we have validated, perfected and expanded the features of the Cryoport Express ® logistics solutions and have now managed 
shipments  of  the  Cryoport  Express  ®  Shippers  through  its  Cryoportal  TM  into  and  out  of  more  than  80  countries  with  more  than  20,000 
shipments, handling a vast array of different biological products and specimens.  

During fiscal year 2012, the Company completed the external validation of its Cryoport Express Standard Shipper to ISTA 7E standards 
and  introduced  the  Cryoport  Express  ®  High  Volume  Shipper  in  response  to  customer  demand.  The  Company  also  set  up  its  European 
distribution depot in Holland to better serve its customer base and support sales efforts in Europe.  

During fiscal year 2013, the Company elected Jerrell Shelton as President and CEO, realigned its sales team, and introduced a solutions 
based  sales  and  operating  strategy.  In  addition,  and  as  part  of  its  global  expansion  plans,  the  Company  set  up  its  Asian  distribution  depot  in 
Singapore.  

Since  the  beginning  of  fiscal  year  2014,  the  Company’s  Board  of  Directors  (“Board”)  has  added  certain  members  to  better  align  the 
experience and competencies of the directors with the Company’s strategic direction. In March 2013, Richard G. Rathmann, a fund manager, 
investor,  and  advisor  to  life  science  companies  over  the  past  20 years,  was  appointed  to  the  Board.   In  September  2013,  Mr. Rathmann  was 
elected Chairman of the Board. Also in September 2013, Mr. Edward Zecchini, an executive with more than thirty years of experience in the 
healthcare  and  information  technology  industries  was  appointed  to  the  Board.  In  June  2014,  Dr.  Ramkumar  Mandalam  was  appointed  to  the 
Board.  Dr.  Mandalam  has  more  than  twenty  years  of  experience  in  the  development  of  biologics  and  is  currently  the  President  and  Chief 
Executive Officer of Cellerant Therapeutics, Inc., a clinical-stage biotechnology company. Most recently, in January 2015, Richard Berman was 
appointed  to  the  Board.  Mr. Berman’s  business  career  consists  of  more  than  35  years  of  venture  capital,  management  and  merger  and 
acquisitions  experience.  The  Company’s  remaining  Board  member,  Jerrell  Shelton,  the  President  and  Chief  Executive  Officer  of  Cryoport, 
joined the Board in October 2012. The Company’s five person Board has four independent Board members, as determined by NASDAQ Rule 
5605(a)(2) and the related rules of the Securities and Exchange Commission.  

Cryoport Express ® Solutions  

Our Cryoport Express ® Solutions are currently made up primarily of the Cryoportal™ software platform, Cryoport Express ® Shippers, 
Cryoport  Express®  Smart  Pak  data  loggers  and  our  life  sciences  cold  chain  logistics  expertise.  Cryoport  Express  ®  Solutions  are  focused  on 
improving the reliability of frozen shipping while reducing our clients’ overall operating costs. This is accomplished by providing complete end-
to-end solutions for the transport and monitoring of frozen or cryogenically preserved biological or other materials shipped primarily through 
distribution partners, such as FedEx, UPS, and DHL, and specialty couriers.  

7 

   
   
    
   
   
   
   
   
   
   
  
The  information  technology  is  centered  on  a  cryogenic  logistics  operating  platform  called  the  Cryoportal  TM  .  which  is  cloud-based. 
Among  its  functions, the  Cryoportal  TM programmatically  assists  in  the  management of  all  aspects  of  the  logistics  operations  beginning  with 
order entry and continuing to monitor, log data, track shipments and store vital information. The Cryoportal TM is capable of producing a variety 
of  Cryoport  Express  ®  Analytics  which  report  shipment  performance  metrics  and  evaluates  temperature-monitoring  data  collected  by  the 
Cryoport Express ® Smart Pak during shipment.  

Cryoport Express ® Solutions are focused on improving the reliability of cryogenic logistics while reducing our clients’ overall operating 
costs. This is accomplished by providing tailored and complete end-to-end solutions for cryogenic logistics requirements including management, 
transport, monitoring and data collection regarding frozen/cryogenically preserved biological commodities or pharmaceutical materials shipped 
primarily though integrators and Cryoport’s logistics network which includes specialty couriers, brokers and other intermediaries. Certain of the 
intellectual  property  underlying  our  Cryoport  Express  ®  Solutions,  other  than  that  related  to  the  Cryoport  Express  ®  Shippers,  has  been,  and 
continues  to  be,  developed  under  a  contract  with  an  outside  software  development  company,  with  the  underlying  technology  licensed  to 
Cryoport for exclusive use in our field of use.  

Cryoportal TM  

The Cryoportal TM is used by Cryoport, our clients and business partners to automate the entry of orders, prepare customs documentation 
and to facilitate status and location monitoring of shipped orders while in transit. It is used by Cryoport to assist in managing logistics operations 
and to reduce administrative costs typically provisioned through manual labor relating to order-entry, order processing, preparation of shipping 
documents and back-office accounting. It is also used to support the high level of customer service expected by the industry. Certain features of 
the Cryoportal TM reduce operating costs and facilitate the scaling of Cryoport’s business, but more importantly they offer significant value to the 
customer  in  terms  of  cost  avoidance  and  risk  mitigation.  Examples  of  these  features  include  automation  of  order  entry,  development  of  Key 
Performance  Indicators  (“KPI’s”)  to  support  our  efforts  for  continuous  process  improvements  in  our  business,  and  programmatic  exception 
monitoring to detect and sometimes anticipate delays in the shipping process, often before the customer or the shipping company becomes aware 
of them.  

The Cryoportal TM also serves as the communications center for the management, collection and analysis of Smart Pak data collected from 
Smart  Pak  data  loggers  in  the  field.  Data  is  converted  into  pre-designed  reports  containing  valuable  and  often  actionable  information  that 
becomes the quality control standard or “pedigree” of the shipment. This information can be utilized by Cryoport to provide valuable feedback to 
our clients relating to their shipments.  

The Cryoportal™ software platform has been developed as a “carrier-agnostic” system, allowing the client and the Cryoport Client Care 
team to work with a single or multiple integrators, freight forwarders, couriers and/or brokers depending on the specific requirements and client 
preferences. To increase operational efficiencies, Cryoportal™ has already been integrated with the tracking systems of FedEx, DHL and UPS 
and we plan to integrate it with other key logistics providers.  

The  Cryoportal  TM  was  developed  for  time-  and  temperature-sensitive  shipments  that  are  required  to  be  maintained  at  specific 
temperatures,  such  as  ambient  (between  20°  and  25°C),  chilled  (between  2°  and  8°C)  or  frozen  (minus  10°C  or  less  all  the  way  down  to 
cryogenic temperatures (minus 150°C) to ensure that the shipped specimen is not subject to degradation or out of its designated “safe” range. 
While our current focus is on cryogenic logistics within the life sciences industry using the logistics solutions described herein, the use of the 
Cryoportal TM can and may be extended into other temperature ranges of the cold chain.  

To our knowledge, the Cryoportal™ software platform is unique to cold chain logistics in the life sciences industry. It is robust and has 
considerable capabilities. It is telling that our strategic alliance partners have chosen to license the Cryoportal™ rather than attempt to duplicate 
its features in their logistics management software. We have engineered the Cryoportal™ in a way that gives us the ability to offer the “ powered 
by Cryoport SM ” strategy as a means to addresss all of the varied needs of our strategic alliance partners.  

The Cryoport Express ® Shippers  

Our Cryoport Express ® Shippers are cryogenic dry vapor shippers capable of maintaining cryogenic temperatures of minus 150° Celsius 
or below for a dynamic shipping period of 10 or more days. A dry vapor cryogenic shipper is a device that uses liquid nitrogen contained inside 
a vacuum insulated vessel which serves as a refrigerant to provide stable storage temperatures below minus 150° Celsius. Our Cryoport Express 
® Shippers are designed to ensure that there is no pressure build up as the liquid nitrogen evaporates. We have developed a proprietary retention 
system to ensure that liquid nitrogen stays inside the vacuum container, which allows the shipper to be designated as a dry vapor shipper meeting 
IATA requirements. Biological or pharmaceutical specimens are stored in a specimen chamber, referred to as a “well” inside the container and 
refrigeration  is  provided  by  gas  evolving  from  the  liquid  nitrogen  entrapped  within  the  proprietary  retention  system.  Specimens  that  may  be 
transported  using  our  cryogenic  shipper  include:  live  cells,  scientific  or  pharmaceutical  commodities  such  as  cancer  vaccines,  diagnostic 
materials,  semen,  eggs,  embryos,  infectious  substances,  and  other  commodities  that  require  continuous  exposure  to  frozen/cryogenic 
temperatures, i.e., temperatures below minus 150° Celsius.  

8 

   
   
   
   
   
   
   
   
   
   
   
  
An important feature of our Cryoport Express ® Shippers, except for the newly introduced Cryoport Express ® CXVC1 Shipper, is their 
compliance  with  the  stringent  packaging  requirements  of  IATA  Packing  Instructions  602  and  650,  respectively.  These  specifications  include 
meeting internal pressure (hydraulic) and drop performance requirements. Under IATA guidelines, Cryoport Express ® Shippers are classified as 
“Non-hazardous.” Dry ice and liquid nitrogen are classified as “Dangerous Goods.” Our shippers are also in compliance with International Civil 
Aviation Organization (“ICAO”) regulations that prohibit egress of liquid nitrogen residue from the shipping packages. The ICAO is a United 
Nations organization that develops regulations for the safe transport of dangerous goods by air.  

We currently offer three sizes of dry vapor shippers, the Cryoport Express ® Standard Shipper with a storage capacity of up to 75 2.0 ml 
vials, the Cryoport Express ® High Volume Shipper, which has a storage capacity of up to 500 2.0 ml vials, and the Cryoport Express ® CXVC1 
Shipper, introduced in August 2014, which has a storage capacity of up to 1,500 2.0 ml vials. Our Cryoport Express® Shippers are composed of 
an aluminum (aircraft-grade) dewar flask, containing a well for holding the high value biological or other materials in its inner chamber and our 
proprietary retention foam that absorbs the liquid nitrogen placed in the shipper to provide it with its extreme cold temperature. The dewar flask 
is vacuum insulated to limit the transmission of heat from outside the flask to the liquid nitrogen captured within the absorption foam and the 
well.  

Cryoport Express ® Standard Shippers  

The  Cryoport  Express  ®  Standard  Shippers  are  lightweight,  low-cost,  re-usable  dry  vapor  liquid  nitrogen  storage  containers  that,  we 
believe,  combine  the  best  features  of  life  sciences  packaging,  cryogenics  science  and  vacuum  insulation  technology.  A  Cryoport  Express  ® 
Standard Shipper is composed of an aluminum metallic dewar flask, with a well for holding the biological material in the inner chamber. The 
dewar vessel is a device in which the conduction, convection and radiation of heat are reduced as much as possible giving it the capability of 
maintaining its contents at a near-constant temperature over relatively long periods of time. The inner chamber of the shipper is surrounded by a 
high surface, low-density material which retains the liquid nitrogen in-situ by absorption, adsorption, and surface tension. Absorption is defined 
as the taking up of matter in bulk by other matter, as in the dissolving of a gas by a liquid, whereas adsorption is the surface retention of solid, 
liquid  or  gas  molecules,  atoms  or  ions  by  a  solid  or  liquid.  This  material  absorbs  liquid  nitrogen  several  times  faster  than  currently  used 
materials, while providing the shipper with a hold time and capacity to transport biological materials safely and conveniently. The annular space 
between the inner and outer dewar walls is evacuated to a very high vacuum (10-6 Torr). The specimen-holding chamber has a primary cap to 
enclose  the  specimens/commodities,  and  a  removable  and  replaceable  secondary  cap  to  further  enclose  the  specimen/commodity-holding 
container  and  to  contain  the  liquid  nitrogen  dry  vapor.  The  entire  dewar  vessel  is  then  wrapped  in  a  plurality  of  insulating  and  cushioning 
materials  and  placed  in  a  disposable  outer  packaging  made  of  recyclable  material.  The  Cryoport  Express  ®  Standard  Shippers  has  a  storage 
capacity of up to 75 2.0 ml vials.  

The technology underlying the Cryoport Express ® Standard Shipper is under constant refinement to further improve its performance and 
reliability.  Our  current  shippers  use  aircraft  grade  aluminum  and  other  lower  weight  materials,  reducing  freight  cost  which  is  based  on 
dimensional-weight.  We  maintain  ongoing  development  efforts  related  to  our  shippers  that  are  principally  focused  on  material  properties, 
particularly  those  properties  related  to  our  low-temperature  requirement,  vacuum  retention  characteristics,  such  as  the  permeability  of  the 
materials,  and  lower  weight  materials  in  an  effort  to  meet  the  life  sciences  market  requirements  for  achieving  the  most  reliable,  lowest  cost, 
frozen and cryogenic logistic solutions.  

Cryoport Express ® High Volume Shippers  

The  Cryoport  Express  ®  High  Volume  Shipper  also  uses  a  dry  vapor  liquid  nitrogen  (LN2)  technology  to  maintain  minus  150°  C 
temperatures  with  a  dynamic  shipping  endurance  of  10 days.  The  Cryoport  Express  ®  High  Volume  Shipper  is based  on  the  same  dry  vapor 
technology as Cryoport’s original standard dry shipper and utilizes an absorbent material to hold LN2, thus providing the extended endurance 
time and IATA validation as a non-hazardous shipping container. The high volume dry shipper is reusable and recyclable, making it a highly 
sustainable and cost effective method of transporting life science materials. The Cryoport Express ® High Volume Shipper has a storage capacity 
of up to 500 2.0ml vials.  

9 

   
   
   
   
   
   
   
   
  
Cryoport Express ® CXVC1 Shippers  

The  Cryoport  Express  ®  CXVC1  Shipper  is  our  largest  shipper  and  can  be  used  either  as  a  dry  vapor  shipper  or  a  liquid  shipper.  It  is 
designed to focus on vaccine ampoules or cryovial shipments in canisters. In the case of dry vapor liquid nitrogen (LN2), it maintains minus 
150°  C  temperatures  with  a  dynamic  shipping  endurance  of  20  days.  In  the  case  of  liquid  nitrogen  (LN2),  it  maintains  minus  150°  C 
temperatures  with  a  shipping  endurance  of  72  days.  The  Cryoport  Express  ®  CXVC1  Shipper,  in  dry  vapor  form,  is  based  on  the  same 
technology as Cryoport’s original standard dry shipper and utilizes an absorbent material to hold LN2, thus providing the extended endurance 
time and IATA validation as a non-hazardous shipping container. The Cryoport Express ® CXVC1 Shipper, in liquid form, is a straightforward 
wet dewar with all the characteristics attendant to a wet dewar and with a holding time of 72 days. The Cryoport Express ® CXVC1 Shipper is 
reusable and recyclable, making it a highly sustainable and cost effective method of transporting life science materials. As a point of reference, 
the Cryoport Express ® CXVC1 Shipper has a storage capacity of up to 1,500 0.2ml vials.  

Cryoport Express ® Shipper Summary  

We  believe  Cryoport  Express  ® Solutions  are  the  best  and  most  cost  effective solution  available  in  the  biotechnology  and  life  sciences 
markets and satisfy customer needs and scientific and regulatory requirements relating to the shipment of time- and temperature-critical, frozen 
and  refrigerated  transport  of  biological  materials,  such  as  stem  cells,  cell  lines,  pharmaceutical  clinical  trial  samples,  gene  biotechnology, 
infectious materials handling, animal and human reproduction markets. Due to our proprietary technology and innovative design, our shippers 
are less prone to losing functional hold time when not kept in an upright position than the competing products because our proprietary dry vapor 
technology and innovative design prevent the spilling or leakage of the liquid nitrogen when the container is tipped or on its side.  

The Cryoport Express ® Smart Pak Temperature Monitoring System  

Temperature monitoring is a high-value feature from our client’s perspective as it is an effective and reliable method to determine that the 
shipment  materials  were  not  damaged  and  did  not  experience  degradation  during  shipment  due  to  temperature  fluctuations.  Our  Smart  Pak 
System consists of a self-contained automated data logger and thermocouple capable of recording cryogenic temperatures of samples shipped in 
our Cryoport Express ® Shippers. The data-logging temperature probe is positioned within the shipper to record the most accurate reading. The 
resultant  temperature  mapping  includes  both  the  temperature  inside  the  chamber  (which  is  closest  to  the  actual  biomaterial)  and  the  external 
temperature.  This  reading,  combined  with  the  mapping  of  shipment  check-in  points,  can  provide  a  holistic  view  of  the  complete  shipping 
process. At the client’s election, shipments can have a full chain-of-custody and chain-of-condition with data monitoring, analysis, and archival 
storage available.  

Chain-of-Condition  

Chain-of-Condition  information  is  essential  for  many  life  sciences  materials,  for  laboratories  and  in  some  cases  for  compliance  with 
regulatory  authorities.  Data  monitoring starts  with our custom  built  data logger (the Cryoport Express  ®  Smart Pak). The Cryoport Express® 
Smart Pak can be set up to report during a shipment and/or after the shipment. For those shipments involving biologics, clinical trials or any 
other  material  that  needs  to  be  verified  before  receiving,  the  information  recorded  by  the  data  logger  can  be  downloaded  to  the  data  station 
onsite.  Alternatively,  Cryoport  can  upload  the  temperature  data  from  the  Cryoport  Express®  Smart  Pak  for  analysis  to  the  Cryoportal  upon 
return of the shipper. The report from the data monitor serves as analysis for temperature monitoring of the entire shipment as well as a tamper 
warning.  The  Cryoportal™  also  acts  as  the  data  repository  for  all  shipment  and  temperature  information,  which  the  customer  can  access 
remotely through the Internet. Chain of condition service provided via Cryoport Express ® Smart Pak is available at the client’s election.  

Chain-of-Custody  

When overlaid with the carrier check-ins, the data monitor and analysis also provides a chain of custody. The report from the data monitor 
serves as analysis for temperature monitoring of the entire shipment as well as a tampering warning. If the client has elected to have chain of 
condition monitoring, each time the container is opened there is a temperature record. The report identifies outlier temperature excursions such 
as  opening  the  shipment  in  customs  or  tampering  and  thus  will  allow  for  more  conclusive  investigations  to  ensure  that  specimens  were  not 
adversely impacted during shipment.  

Cryoport Express ® Analytics  

Cryoport  Express  ®  Analytics  information  is  captured  by  the  Cryoportal™  to  provide  us  and  our  customers’  access  to  important 
information from the shipments recorded in the Cryoportal™ to assist in management of our customers’ shipping. For us, we use the information 
to support planned future features to allow for an expansion of our solutions offering. Analytics is a term used by IT professionals to refer to 
performance benchmarks or Key Performance Indicators that management utilizes to measure performance against desired standards. Examples 
for  analytics  tracked  through  the  Cryoportal™  include  time-based  metrics  for  order  processing  time  and  on-time  deliveries  by  our  shipping 
partners, as well as profiling shipping lanes to determine average transit times and predicting potential shipping exceptions based on historical 
metrics. The analytical results are being utilized by Cryoport to render consultative and proactive client services.  

10 

   
   
   
   
   
   
   
   
   
   
   
   
   
  
Biological Material Holders  

A  patented  containment  bag  is  used  in  connection  with  the  shipment  of  infectious  or  dangerous  goods  using  the  Cryoport  Express  ® 
Shippers. Up to 75 cryovials (polypropylene vials with high-density polyethylene closures), set on aluminum canes are placed into an absorbent 
pouch, which is designed to contain the entire contents of all the vials in the event of leakage. This pouch is then placed in a watertight Tyvek 
bag  (secondary  packaging)  capable  of  withstanding  cryogenic  temperatures,  and  then  sealed.  This  bag  is  then  placed  into  the  well  of  the 
Cryoport Express ® Shipper.  

Logistics Expertise and Support  

Cryoport’s  client  services  professionals  provide  24/7/365  live  logistics  and  monitoring  services  with  specialized  knowledge  in  the 
domestic  and  global  logistics  of  life  sciences  material  requiring  cryogenic  temperatures.  The  Cryoport  logistics  professionals  have  validated 
shipping lanes in and out of more than 80 countries to date to ensure shipments maintain cryogenic temperatures and arrive securely and on time. 

Other Development Activities  

We  are  continuing  our  research  and  development  efforts  to  further  refine  our  current  technology  as  well  as  explore  opportunities  with 
partners to offer complementary packaging solutions for frozen temperature (minus 10° Celsius or less), chilled temperature (2° to 8° Celsius) 
and ambient temperature (between 20° and 25° Celsius) shipping markets.  

We also continue to further expand the functionality of our Cryoportal TM to ensure a high level of effectiveness and efficiency in the cold 

chain logistics process and to allow for intelligent and easy data monitoring and analysis.  

Government Regulation  

The shipping of diagnostic specimens, infectious substances and dangerous goods, whether via air or ground, falls under the jurisdiction of 
many  state,  federal  and  international  agencies.  The  quality  of  the  containers,  packaging  materials  and  insulation  that  protect  a  specimen 
determine whether or not it will arrive in a usable condition. Many of the regulations for transporting dangerous goods in the United States are 
determined by international rules formulated under the auspices of the United Nations.  

The  International  Civil  Aviation  Organization  (“ICAO”)  is  the  United  Nations  organization  that  develops  regulations  (Technical 
Instructions) for the safe transport of dangerous goods by air. If shipment is by air, compliance with the rules established by International Air 
Transport Association (“IATA”) is required. IATA is a trade association made up of airlines and air cargo couriers that publishes annual editions 
of the IATA Dangerous Goods Regulations. These regulations interpret and add to the ICAO Technical Instructions to reflect industry practices. 
Additionally, the Centers for Disease Control (“CDC”) has regulations (published in the Code of Federal Regulations) for interstate shipping of 
specimens, and OSHA also addresses the safe handling of Class 6.2 Substances.  

Our Cryoport Express ® Shippers meet Packing Instructions 602 and 650 and are certified for the shipment of Class 6.2 Dangerous Goods 
per the requirements of the ICAO Technical Instructions for the Safe Transport of Dangerous Goods by Air and IATA. Our present and planned 
future  versions  of  the Cryoport  Smart Pak  data logger  will likely be  subject to  regulation by  the FAA, FCC, FDA, IATA  and  possibly other 
agencies which may be difficult to determine on a global basis.  

We  are also  subject  to  numerous  other  federal,  state  and local  laws  relating  to  such  matters  as  safe  working  conditions,  manufacturing 
practices, environmental protection, fire hazard control, and disposal of hazardous or potentially hazardous substances. We may incur significant 
costs to comply with such laws and regulations now or in the future.  

Manufacturing and Raw Materials  

Manufacturing  .  Due  to  our  sufficient  level  of  dewar  inventories,  we  are  not  manufacturing  at  this  time.  The  component  parts  for  our 
shippers are primarily manufactured at third party manufacturing facilities. We also have a warehouse at our facility in Lake Forest, California, 
where we are capable of manufacturing certain parts and to fully assemble our shippers. Most of the components that we use in the manufacture 
of our shippers are available from more than one qualified supplier. For some components, however, there are relatively few alternate sources of 
supply  and  the  establishment  of  additional  or  replacement  suppliers  may  not  be  accomplished  immediately,  however,  we  have  identified 
alternate  qualified  suppliers.  Should  this  occur,  we  believe  that  with  our  current  level  of  shippers,  we  have  enough  inventory  to  cover  our 
forecasted demand.  

11 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
There are no specific agreements with any manufacturer nor are there any long term commitments to any manufacturer. We believe that 
most  of  the  manufacturers  currently  used  by  us  could  be  replaced  within  a  short  period  of  time  as  none  have  a  proprietary  component  or  a 
substantial capital investment specific to our shippers.  

Our production and manufacturing process incorporates innovative technologies developed for aerospace and other industries which are 
cost  effective,  easier  to  use  and  more  functional  than  the  traditional  dry  ice  devices  and  other  methods  currently  used  for  the  shipment  of 
temperature-sensitive  materials.  Our  manufacturing  process  uses  non-hazardous  cleaning  solutions,  which  are  provided  and  disposed  of  by  a 
supplier approved by the Environmental Protection Agency (the “EPA”). EPA compliance costs for us are therefore negligible.  

Cryoport Express ® High Volume Shippers are purchased from a third party and modified to meet our specifications using our proprietary 

technology and know-how.  

Our  data  loggers  have  been  acquired  from  a  single  source  with  the  calibration  done  by  an  independent  third  party.  We  are  currently 

considering adding alternate data loggers with greater range of functionality.  

Raw Materials . Various common raw materials are used in the manufacture of our shippers and in the development of our technologies. 
These  raw  materials  are  generally  available  from  several  alternate  distributors  and  manufactures.  We  have  not  experienced  any  significant 
difficulty in obtaining these raw materials and we do not consider raw material availability to be a significant factor in our business.  

Patents and Proprietary Rights  

In  order  to  remain  competitive,  we  must  develop  and  maintain  protection  on  the  proprietary  aspects  of  our  technologies.  We  rely  on  a 
combination of patents, copyrights, trademarks, trade secret laws and confidentiality agreements to protect our intellectual property rights. We 
currently  own  three  registered  U.S.  trademarks  and  three  issued  U.S.  patents  primarily  covering  various  aspects  of  our  Cryoport  Express  ® 
Shippers.  

In addition, we have a pending U.S. patent application for various aspects of our shipper and web-portal, which includes, in part, various 
aspects of our business model referred to as the Cryoport Express® System. We have also filed a U.S. provisional patent application for a smart 
label which will communicate electronically with our data logger. We intend to file additional patent applications to strengthen our intellectual 
property rights.  

The  technology  covered  by  the  above  indicated  issued  patents  relates  to  matters  specific  to  the  use  of  liquid  nitrogen  shippers  in 
connection with the shipment of biological materials. The concepts include those of disposability, package configuration details, liquid nitrogen 
retention  systems,  systems  related  to  thermal  performance,  systems  related  to  packaging  integrity,  and  matters  generally  relevant  to  the 
containment  of  liquid  nitrogen.  Similarly,  the  trademarks  mentioned  relate  to  the  cryogenic  temperature  shipping  activity.  Issued  patents  and 
trademarks currently owned by us and a patent application include:  

Type: 
Patent 
Patent 
Patent 
Patent Application  
Trademark 
Trademark 
Trademark 

  No. 

    Issued 

6,467,642     Oct. 22, 2002 
6,119,465     Sep. 19, 2000 
6,539,726     Apr. 1, 2003 

12/656,641       

  Expiration 
  Jan. 2, 2021 
  Feb. 10, 2019 
  May 8, 2021 

3,569,471     Feb. 3, 2009 
3,589,928     Mar. 17, 2009 
2,632,328     Oct. 8, 2002 

  Feb. 3, 2019 
  Mar. 17, 2019 
  Oct. 8, 2022 

Our  success  depends  in  part  upon  our  ability  to  develop  proprietary  products  and  technologies  and  to  obtain  patent  coverage  for  these 
products  and  technologies.  We  intend  to  file  trademark  and  patent  applications  covering  any  newly  developed  products,  methods  and 
technologies. However, there can be no guarantee that any of our pending or future filed applications will be issued as patents. There can be no 
guarantee that the U.S. Patent and Trademark Office or some third party will not initiate an interference proceeding involving any of our pending 
applications or issued patents. Finally, there can be no guarantee that our issued patents or future issued patents, if any, will provide adequate 
protection from competition.  

12 

   
   
   
    
   
   
   
   
   
   
   
   
  
    
    
    
    
    
    
    
    
Patents  provide  some  degree  of  protection  for  our  proprietary  technology.  However,  the  pursuit  and  assertion  of  patent  rights  involve 
complex  legal  and  factual  determinations  and,  therefore,  are  characterized  by  significant  uncertainty.  In  addition,  the  laws  governing  patent 
issuance  and  the  scope  of  patent  coverage  continue  to  evolve.  Moreover,  the  patent  rights  we  possess  or  are  pursuing  generally  cover  our 
technologies to varying degrees. As a result, we cannot ensure that patents will issue from any of our patent applications, or that any of its issued 
patents will offer meaningful protection. In addition, our issued patents may be successfully challenged, invalidated, circumvented or rendered 
unenforceable so that our patent rights may not create an effective barrier to competition. Moreover, the laws of some foreign countries may not 
protect our proprietary rights to the same extent as the laws of the United States. There can be no assurance that any patents issued to us will 
provide  a  legal  basis  for  establishing  an  exclusive  market  for  our  products  or  provide  us  with  any  competitive  advantages,  or  that  patents  of 
others will not have an adverse effect on our ability to do business or to continue to use our technologies freely.  

We may be subject to third parties filing claims that our technologies or products infringe on their intellectual property. We cannot predict 
whether third parties will assert such claims against us or whether those claims will hurt our business. If we are forced to defend against such 
claims, regardless of their merit, we may face costly litigation and diversion of management’s attention and resources. As a result of any such 
disputes, we may have to develop, at a substantial cost, non-infringing technology or enter into licensing agreements. These agreements may be 
unavailable on terms acceptable to such third parties, or at all, which could seriously harm our business or financial condition.  

We  also  rely  on  trade  secret  protection  of  our  intellectual  property.  We  attempt  to  protect  trade  secrets  by  entering  into  confidentiality 
agreements with third parties, employees and consultants, although, in the past, we have not always obtained such agreements. It is possible that 
these  agreements  may be  breached,  invalidated  or rendered  unenforceable, and if  so,  our  trade  secrets could be  disclosed  to our  competitors. 
Despite the measures we have taken to protect our intellectual property, parties to such agreements may breach confidentiality provisions in our 
contracts or infringe or misappropriate our patents, copyrights, trademarks, trade secrets and other proprietary rights. In addition, third parties 
may  independently  discover  or  invent  competitive  technologies,  or  reverse  engineer  our  trade  secrets  or  other  technology.  Therefore,  the 
measures we are taking to protect our proprietary technology may not be adequate.  

Customers and Distribution  

As a result of growing globalization, including such areas as biotechnology and life science, clinical trials, distribution of pharmaceutical 
products and reproductive medicine, the requirement for effective and reliable solutions for keeping clinical samples, pharmaceutical products 
and other specimen at frozen temperatures takes on added significance due to more complex shipping routes, extended shipping times, custom 
delays and logistics challenges. Today, such specimens are traditionally shipped in styrofoam cardboard insulated containers packed with dry 
ice, gel/freezer packs or a combination thereof. The current dry ice solutions have limitations that severely limit their effective use for both short 
and  long-distances  (e.g.,  international).  Conventional  dry  ice  shipments  often  require  labor-intensive  “re-icing”  operations  resulting  in  higher 
labor and shipping costs.  

We  believe  our  patented  Cryoport  Express  ®  Shippers,  the  Cryoportal™  and  our  logistics  expertise  make  us  well  positioned  to  take 
advantage of the growing demand for effective and efficient international transport of temperature sensitive materials resulting from continued 
globalization. Of particular significance is the trend within the life sciences and biotechnology industries toward globalization.  

We provide domestic shipping solutions in situations where specimens must be kept at frozen temperatures and in regions where there is a 

high priority placed on maintaining the integrity of materials shipped at these temperatures.  

Pharmaceutical Clinical Trials . Every United States based pharmaceutical company developing a new drug must seek drug development 
protocol approval by the FDA. These clinical trials are to test the safety and efficacy of the potential new drug among other things. A significant 
amount of clinical trial activity is managed by a number of large Clinical Research Organizations (“CROs”).  

In connection with the clinical trials, due to globalization, companies can be enrolled from all over the world and may need to regularly 
submit a blood or other specimen at the local hospital, doctor’s office or laboratory. These samples are then sent to specified testing laboratories, 
which  may  be  local  or  in  another  country.  The  testing  laboratories  will  typically  set  the  requirements  for  the  storage  and  shipment  of  blood 
specimens.  In  addition,  drugs  used  by  the  patients  may  require  frozen  shipping  to  the  sites  of  the  clinical  trials.  While  both  domestic  and 
international shipping of these specimens is accomplished using dry ice today, international shipments especially present several problems, as 
dry ice, under the best of circumstances, can only provide freezing for one to two days in the absence of re-icing (which is quite costly). Because 
shipments of packages internationally can take longer than one to two days or be delayed due to flight cancellations, incorrect destinations, labor 
problems,  ground  logistics,  customs  delays  and  safety  reasons,  dry  ice  is  not  always  a  reliable  and/or  cost  effective  option.  Clinical  trial 
specimens  are  often irreplaceable because each one represents clinical data at  a prescribed  point in  time, in a  series  of  specimens on  a given 
patient, who may be participating in a trial for years. Sample integrity during the shipping process is vital to retaining the maximum number of 
patients  in  each  trial.  Our  shippers  are  ideally  suited  for  this  market,  as  our  longer  hold  time  ensures  that  specimens  can  be  sent  over  long 
distances with minimal concern that they will arrive in a condition that will cause their exclusion from the trial. There are also many instances in 
domestic shipments where Cryoport Express ® Shippers will provide higher reliability and be cost effective.  

13 

   
   
   
   
   
   
   
   
   
   
  
Furthermore, the IATA requires that all airborne shipments of laboratory specimens be transmitted in either IATA Instruction 650 or 602 
certified  packaging.  We  have  developed  and  obtained  IATA  certification  of  our  Cryoport  Express  ®  System,  which  is  ideally  suited  for  this 
market, in particular due to the elimination of the cost to return the reusable shipper.  

Biotechnology  and  Diagnostic  Companies  .  The  biotechnology  market  includes  basic  and  applied  research  and  development  in  diverse 
areas such as stem cells, cloning, gene therapy, DNA tumor vaccines, tissue engineering, genomics, and blood products. Companies participating 
in  the  foregoing  fields  rely  on  the  frozen  transport  of  specimens  in  connection  with  their  research  and  development  efforts,  for  which  our 
Cryoport Express ® Shippers are ideally suited.  

Cell  Therapy  Companies.  Rapid  advancements  are  underway  in  the  research  and  development  of  cell  based  therapies,  which  involve 
cellular material being injected into a patient. In allogeneic cell therapy, the donor is a different person to the recipient of the cells. Autologous 
cell therapy is a therapeutic intervention that uses an individual’s cells, which are cultured and expanded outside the body, and reintroduced into 
the donor. Once cells are processed, in either case, they must be shipped cryogenically for which our Cryoport Express ® Shippers are ideally 
suited.  

Central Laboratories. With the increase and globalization of clinical studies and trials, logistics has become more complex and ensuring 
sample integrity has become more challenging. International courier costs are now consuming a significant portion of global protocol budgets. 
We believe laboratories performing the testing of samples collected during the conduct of these global multi-site studies are looking for reliable 
state-of-the-art logistics solutions.  

Pharmaceutical Distribution . The current focus for the Cryoport Express ® System also includes the area of pharmaceutical distribution. 
There are a significant number of therapeutic drugs and vaccines currently or anticipated soon to be undergoing clinical trials. After the FDA 
approves them for commercial marketing, it will be necessary for the manufacturers to have a reliable and economical method of distribution to 
the physician who will administer the product to the patient. It is likely that the most efficient and reliable method of distribution will be to ship a 
single  dosage  to  the  administering  physician.  These  drugs  are  typically identified to  individual  patients  and  therefore  will require  a  complete 
tracking history from the manufacturer to the patient. The most reliable method of doing this is to ship a unit dosage specifically for each patient. 
If such drugs require maintenance at frozen or cryogenic temperatures, each such shipment will require a frozen or cryogenic shipping package. 
Cryoport can provide the technology to meet this anticipated need.  

Distribution of Vaccines and Biologic Therapies. There are a variety of vaccines and other drugs or therapies that require distribution at 
frozen or cryogenic temperatures. We anticipate significant growth in this area, in particular therapies based upon stem cells. It is likely that the 
most  efficient  and  reliable  method  of  distribution  will  be  to  ship  a  single  dosage  or  a  limited  supply  to  the  physician  for  administration  to  a 
patient.  

In February 2013, we started providing comprehensive logistics management services for the lead poultry vaccine distribution of Zoetis, 

Inc. In October 2013, Zoetis engaged us to manage distribution of an additional vaccine.  

One of our strategic alliance partners, Liventa Bioscience, Inc., is, in part, basing its business strategy on using our Cryoport Express  ® 
Shippers to deliver supplies of cell-based therapies to physicians, which will be able to keep the shippers at the physician’s facility for up to one 
week and thus avoid the need to invest in costly cryogenic refrigeration equipment for commodity storage. With the inclusion of our Cryoport 
Express ® Smart Pak data logger, Liventa and the physician will have assurance that cryogenic temperatures were maintained within the shipper.  

Fertility  Clinics  and  In  Vitro  Fertilization  (“IVF”)  .  Maintaining  cryogenic  temperatures  during  shipping  and  transfer  of  in  vitro 
fertilization  specimens  like  eggs,  sperm,  or  embryos  is  critical  for  cell  integrity  in  order  to  retain  viability,  stabilize  the  cells,  and  ensure 
reproducible  results  and  successful  IVF  treatment.  There  are  approximately  3,300  fertility  clinics  worldwide.  Cryoport  anticipates  that  this 
market will continue to grow; in the United States alone, the fertility market has grown to more than $4.0 billion with over 1.3 million women 
seeking treatment each year. In the worldwide market, it is reported that there are more than one billion IVF cycles per year and growing.  

Sales and Marketing  

We  currently  have  five  sales  directors  in  the  United  States,  one  sales  director  in  Europe,  one  inside  sales  representative  focused  on 
Reproductive Medicine/IVF and a part time senior director of marketing promoting the use of our Cryoport Express® Solutions on a direct basis. 
In addition, we have a vice president of strategic business development that focuses on large corporate accounts. Given the global nature of our 
business,  we  are  also  establishing  distribution  channels  to  broaden  our  sales  and  marketing  reach  in  the  Americas,  Europe  and  Asia.  For  the 
fiscal years ended March 31, 2015 and 2014, we had one customer that accounted for 22.7% and 30.8%, respectively, of total revenues. No other 
single customer generated over 10% of our total revenues during 2015 and 2014.  

14 

   
    
   
   
   
   
   
   
   
   
   
   
  
Our geographical revenues for the fiscal year ended March 31, 2015 were as follows:  

USA 
Europe 
Asia 
Rest of World 

84.3 % 
7.5 % 
1.9 % 
6.3 % 

We renewed our  agreement with  FedEx  and  entered  into  agreements  with UPS  and DHL to further  expand  our revenue  and marketing 
opportunities  and  plan  to  establish  additional  strategic  partnerships  with  integrators  and  freight  forwarders.  Subject  to  available  financial 
resources, we also plan to hire additional sales and marketing personnel and implement marketing initiatives intended to increase awareness of 
the Cryoport Express ® Solutions.  

Cryoport Operations Centers  

In addition to the services provided through our facility in Lake Forest, California, we have contracted with third parties to run our 
European Operations Center (located in Rotterdam, Holland) and Asian Operations Center (located in Singapore). The operations centers 
provide warehousing, shipping, receiving, refurbishing and recycling services for our shipping containers. This approach is a cost-effective way 
to initiate operations outside of the US and allows us to scale up as our business grows globally.  

Industry and Competition  

Our products and services are sold into a rapidly growing segment of the logistics industry focused on the temperature sensitive packaging 
and shipping of biological materials. Expenditures for “value added” packaging for frozen transport have been increasing for the past several 
years and, due in part to continued globalization, are expected to continue to increase even more in the future as more domestic and international 
biotechnology  firms  introduce  pharmaceutical  products  that  require  continuous  refrigeration  at  cryogenic  temperatures.  We  believe  this  will 
require a greater dependence on passively controlled temperature transport systems (i.e., systems having no external power source). In addition, 
we expect that industry standards and regulations will be introduced globally, requiring more comprehensive tracking and validation of shipping 
temperatures.  

We believe that growth in the following markets has resulted in the need for increased reliability, efficiencies and greater flexibility in the 

temperature sensitive segment of the logistics market:  

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

cell-based therapies 

gene and stem cell biotechnology 

cell lines 

vaccine production 

commercial drug product distribution 

clinical trials, including transport of tissue culture samples 

diagnostic specimens 

infectious sample materials 

inter/intra-laboratory diagnostic testing 

temperature-sensitive specimens 

biological samples, in general 

environmental sampling 

IVF 

animal husbandry 

15 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
    
    
    
    
  
  
  
  
  
  
  
  
  
  
  
  
  
Many of the biological products in these above markets require transport in a frozen state as well as the need for shipping containers which 
have the ability to maintain a frozen, cryogenic environment (e.g., minus 150° Celsius) for a period ranging from two to ten days (depending on 
the distance and mode of shipment). These products include stem cells, semen, embryo, tissue, tissue cultures, cultures of viruses and bacteria, 
enzymes, DNA materials, vaccines and certain pharmaceutical products.  

One of the integral parts of our solutions are our Cryoport Express ® Shippers that are based on a liquid nitrogen dry vapor technology. 
The  following  paragraphs  compare  our  shippers  with  dry  ice  and  liquid  nitrogen  shipping  methods.  Our  solutions  integrate  the  Cryoport 
Express®  Shippers  with  our  Cryoportal  TM  logistics  software  platform  and  our  cold  chain  logistics  know-how  that  are  comprehensive  and 
tailored to client requirements.  

Cryoport Express Shippers (Liquid Nitrogen Dry Vapor) compared to Dry Ice Shipments  

One  problem  faced  by  many  companies  operating  in  these  specialized  markets  is  the  limited  number  of  cryogenic  shipping  systems 
serving their needs. The currently adopted protocol and the most common method for packaging frozen transport in these industries is the use of 
solid-state carbon dioxide (dry ice). Dry ice is and has been used extensively in shipping to maintain a frozen state for a period of one to four 
days.  Dry  ice  is  used  in  the  transport  of  many  biological  products,  such  as  pharmaceuticals,  laboratory  specimens  and  certain  infectious 
materials.  The  common  approach  to  shipping  these  items  via  ground  freight  is  to  pack  the  product  in  a  container,  such  as  an  expanded 
polystyrene (styrofoam) box or a molded polyurethane box, with a variable quantity of dry ice. The box is taped or strapped shut and shipped to 
its destination with freight charges based on its initial shipping weight. All dry ice shipping is considered dangerous goods shipping, requiring 
extra packaging steps and adding costs. It gives off carbon dioxide and sublimates unevenly and in short duration.  

With respect to shipments via specialized courier services, there is no standardized method or device currently in use for the purpose of 
transporting  temperature-sensitive  frozen  biological  specimens.  One  common  method  for  courier  transport  of  biological  materials  is  to  place 
frozen specimens, refrigerated specimens, and ambient specimens into a compartmentalized container, similar in size to a 55 quart Coleman or 
Igloo  cooler.  The  freezer  compartment  in  the  container  is  loaded  with  a  quantity  of  dry  ice  at  minus  78°  Celsius,  while  the  refrigerated 
compartment at 8° Celsius utilizes ice substitutes.  

Two manufacturers of the polystyrene and polyurethane containers frequently used in the shipping and courier transport of dry ice frozen 
specimens are Insulated Shipping Containers, Inc. and Tegrant (formerly SCA Thermosafe). When these containers are used with dry ice, the 
average sublimation rate (e.g., the rate at which dry ice turns from a solid to a gaseous state) in a container with a 1 1 / 2 inch wall thickness is 
slightly less than three pounds per 24 hours. Other existing refrigerant systems employ the use of gel packs and ice substitutes for temperature 
maintenance. Gels and eutectic solutions (phase changing materials) with a wide range of phasing temperatures have been developed in recent 
years to meet the needs of products with varying specific temperature control requirements.  

The  use  of  dry  ice  and  ice  substitutes,  however,  regardless  of  external  packaging  used,  are  frequently  inadequate  because  they  do  not 
provide low enough storage temperatures and, in the case of dry ice, last for only a few days without re-icing. As a result, companies run the risk 
of increased costs due to lost specimens and additional shipping charges due to the need to re-ice.  

Some of the other disadvantages to using dry ice for shipping or transporting temperature sensitive products are as follows:  

• 

• 

• 

• 

• 

• 

• 

availability of a dry ice source; 

handling and storage of the dry ice; 

cost of the dry ice; 

compliance with local, state and federal regulations relating to the storage and use of dry ice; 

dangerous goods shipping regulations; 

weight of containers when packed with dry ice; 

securing a shipping container with a high enough R-value (which is a measure of thermal resistance) to hold the dry ice and 
product for the required time period; 

16 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
• 

• 

securing a shipping container that meets the requirements of IATA, the DOT, the CDC, and other regulatory agencies; and 

emission of greenhouse gases (primarily carbon dioxide) into the environment. 

Due to the limitations of dry ice, specimens that require frozen shipping are more securely shipped at true cryogenic temperatures using a 
service  such  as  liquid  nitrogen  dry  vapor  shippers  (Cryoport  Express  Shippers),  or  liquid  nitrogen  shippers  where  the  specimen  is  kept  over 
actual liquid nitrogen. However, liquid nitrogen is hazardous and has many pitfalls including safety and expense.  

Cryoport Express Shippers (Liquid Nitrogen Dry Vapor) compared to Liquid Nitrogen Dewars/Tanks  

There  are  distinct  disadvantages  when  using  liquid  nitrogen  compared  to  the  dry  vapor  liquid  nitrogen  used  in  Cryoport  Express  ® 
Shippers. Liquid nitrogen dewars/tanks are classified as dangerous goods and cannot be shipped as parcel. In addition, the liquid nitrogen has to 
be disposed of prior to returning the dewar/tank to its origin. These issues add additional procedural steps and costs to the shipment. In addition, 
there is a risk of liquid nitrogen leakage if the dewar/tank tips to the side during transport, which can cause bodily injury and compromise the 
specimen being shipped. Due to the use of our proprietary technology, our Cryoport Express ® Shippers are not prone to leakage when on their 
side or inverted, thereby protecting the integrity of our shipper’s hold time and being safe for handling.  

While both liquid nitrogen dry vapor and liquid nitrogen shippers provide solutions to the issues encountered when shipping with dry ice, 
liquid nitrogen shippers have some draw backs. For example, the cost for a liquid nitrogen shipper typically can range from $650 to $4,000 per 
unit, which can substantially limit their use for the transport of many common biologics, particularly with respect to small quantities such as is 
the case with direct to the physician drug delivery. Because of the initial cost and limited production of these containers, they are designed to be 
reusable.  However,  the  cost  of  returning  these  containers  can  be  significant,  particularly  in  international  markets,  because  most  applications 
require  only one-way  shipping. In addition,  the logistics support  of  cryogenic  shippers requires more  sophisticated logistics  management  and 
discipline to ensure shippers are returned and recycled, especially for international shipments, which many companies do not have in place.  

Cryoport’s solutions are totally comprehensive and integrated for maximum reliability, economy and total effectiveness. Cryoport’s total 
logistics  solution  enables  life  sciences  companies  to  utilize  the  superior  liquid  nitrogen dry vapor  technology  without  having  to  make  capital 
investments or developing in-house logistics expertise and systems by offering a complete solution, which includes the cloud-based Cryoportal 
TM  logistics  management  platform,  the  temperature  monitoring  system  and  the  24/7/365  logistics  support.  Cryoport  allows  the  customer  to 
outsource logistics and focus on its core competencies while maintaining visibility of all shipping related information.  

Within our intended biotechnology and life sciences markets for Cryoport Express ® Shippers, there is limited known direct competition. 
We  compete  with  liquid  nitrogen  and  dry  ice  solutions  by  reason  of  the  improved  and  integrated  hardware  and  software  technology  in  our 
products including our comprehensive logistics management software and through the use of our service enabled business model. The Cryoport 
Express ® Solution provides a simple and cost effective solution for the frozen or cryogenic transport of biotech and life sciences materials. The 
Cryoportal TM assists with the management, scheduling and shipping of the Cryoport Express ® Shippers, removing the burdens associated with 
other methods.  

Traditional  dry  ice  shippers  and  liquid  nitrogen  tank  suppliers,  such  as  MVE/Chart  Industries,  Taylor  Wharton,  and  Air  Liquide,  offer 
various  models  of  dry  vapor  liquid  nitrogen  shippers  that  are  not  as  cost  efficient  for  multi-use  and  multi-shipment  purposes  due  to  their 
significantly greater unit costs and unit weight (which may substantially increase the shipping cost). On the other hand, they are more established 
and  have  larger  organizations  and  have  greater  financial,  operational,  sales  and  marketing  resources,  have  a  broader  manufactured  product 
offering of other liquid nitrogen products and more experience in research and development than we do.  

Factors that we believe give us a competitive advantage are attributable to our software and shipping containers, which allow our shipper 
to retain liquid nitrogen when placed in non-upright positions, the overall “leak-proofness” of our package which determines compliance with 
shipping regulations, the overall weight and volume of the package which determines shipping costs, and our business model represented by the 
merged integration of our shipper with Cryoportal TM and Smart Pak data logger into a seamless shipping, tracking and monitoring solution.  

17 

    
   
   
   
   
   
   
   
   
   
   
  
  
  
Other companies that offer potentially competitive products include Industrial Insulation Systems, which offers cryogenic transport units 
and  has  partnered  with  Marathon  Products  Inc.,  a  manufacturer  and  global  supplier  of  wireless  temperature  data  collecting  devices  used  for 
documenting  environmentally  sensitive  products  through  the  cold  chain,  and  Kodiak  Thermal  Technologies,  Inc.  which  offers,  among  other 
containers,  a  repeat  use  active-cool  container  that  uses  free  piston  stirling  cycle  technology.  While  not  having  their  own  shipping  devices, 
BioStorage Technologies is potentially a competitive company through their management services offered for cold-chain logistics and long-term 
biomaterial storage. Cryogena offers a single use disposable LN2 shipper with better performance than dry ice, but it does not perform as well 
and  is  not  as  cost-effective  as  the  Cryoport  solution  when  all  costs  are  considered.  In  addition,  BioMatrica,  Inc.  is  developing  and  offering 
technology that stabilizes biological samples and research materials at room temperature. They presently offer these technologies primarily to 
research and academic institutions; however, their technology may eventually enter the broader cold-chain market. Fisher BioServices, part of 
Thermo Fisher Scientific, provides cell therapy logistics services, maintaining cold chain from manufacturer to patient bedside.  They provide 
customized solutions in biospecimen collection kits, biospecimen shipping, lab processing, biobanking and clinical trial support services.  

Research and Development  

Our research and development efforts are focused on continually improving the features of our Cryoport Express ® Solutions including the 
cloud-based Cryoportal  TM and the Cryoport Express  ® Shippers. These efforts are expected to lead to the introduction of shippers of varying 
sizes  based  on  market  requirements,  constructed  of  lower  cost  materials  and  utilizing  high  volume  manufacturing  methods  that  will  make  it 
practical to provide the cryogenic packages offered with the Cryoport Express ® Solutions. Alternative phase change materials in place of liquid 
nitrogen  may  be  used  to  increase  the  potential  markets  these  shippers  can  serve  such  as  ambient  and  2°-  8°C  markets.  Our  research  and 
development expenditures for the fiscal years ended March 31, 2015 and 2014 were $352,600 and $409,100, respectively with the largest portion 
being spent on software maintenance and development.  

Employees  

The  efforts  of  our  employees  are  critical  to  our  success.  We  believe  that  we  have  assembled  a  strong  management  team  with  the 
experience and expertise needed to execute our business strategy. We anticipate hiring additional personnel as needs dictate to implement our 
growth strategy. As of May 8, 2015, we had twenty seven full-time employees, four consultants and five temporary employees.  

Insurance  

We currently maintain general liability insurance, with coverage in the amount of $1 million per occurrence, subject to a $2 million annual 
limitation.  Claims  may  be  made  against  us  that  exceed  these  limits.  In  fiscal  year  2015,  we  did  not  experience  any  claims  against  our 
professional  liability  insurance.  Our  liability  policy  is  an  “occurrence”  based  policy.  Thus,  our  policy  is  complete  when  we  purchased  it  and 
following cancellation of the policy it continues to provide coverage for future claims based on conduct that took place during the policy term. 
However, our insurance may not protect us against all liability because our policies typically have various exceptions to the claims covered and 
also  require  us  to  assume  some  costs  of  the  claim  even  though  a  portion  of  the  claim  may  be  covered.  In  addition,  if  we  expand  into  new 
markets, we may not be aware of the need for, or be able to obtain insurance coverage for such activities or, if insurance is obtained, the dollar 
amount  of  any  liabilities  incurred  could  exceed  our  insurance  coverage.  A  partially  or  completely  uninsured  claim,  if  successful  and  of 
significant magnitude, could have a material adverse effect on our business, financial condition and results of operations.  

We also maintain product liability insurance with coverage in the amount of $1,000,000 per year. In addition, we currently maintain cargo 

insurance for shipments for one customer, with coverage of up to $10,000 per shipment.  

ITEM 1A.  RISK FACTORS 

This Annual Report on Form 10-K contains forward-looking information based on our current expectations. Because our actual results 
may differ materially from any forward-looking statements made by or on behalf of Cryoport, this section includes a discussion of important 
factors that could affect our actual future results, including, but not limited to, our potential product and service revenues, acceptance of our 
products and services, expenses, net income(loss) and earnings(loss) per common share.  

Risks Related to Our Financial Condition  

We have incurred significant losses to date and may continue to incur losses.  

We have incurred net losses in each fiscal year since we commenced operations. The following table represents net losses incurred for 

each of our last two fiscal years:  

Fiscal Year Ended March 31, 2015 
Fiscal Year Ended March 31, 2014 

   Net Loss 
  $ 
  $ 

7,026,900   
19,565,400   

18 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
    
  
  
  
Our  fiscal  year  ended  March  31,  2014  loss  of  $19,565,400  included  a  one-time  non-cash  loss  of  $13,713,800  as  a  result  of  an  induced  debt 
conversion expense as described in Management's Discussion and Analysis of Financial Condition and Results of Operations under the “Results 
of Operations for Fiscal 2015 Compared to Fiscal 2014” section. As of March 31, 2015, we had an accumulated deficit of $97.8 million. In order 
to achieve and sustain such revenue growth in the future, we must significantly expand our market presence and revenues from existing and new 
customers.  We  may  continue  to  incur  losses  in  the  future  and  may  never  generate  revenues  sufficient  to  become  profitable  or  to  sustain 
profitability. Continuing losses may impair our ability to raise the additional capital required to continue and expand our operations.  

Our auditors have expressed doubt about our ability to continue as a going concern.  

The  Report  of  Independent  Registered  Public  Accounting  Firm  to  our  March  31,  2015  consolidated  financial  statements  includes  an 
explanatory paragraph stating that the recurring losses and negative cash flows from operations since inception and our cash and cash equivalent 
balance at March 31, 2015 raise substantial doubt about our ability to continue as a going concern. The consolidated financial statements do not 
include any adjustments that might result from the outcome of this uncertainty.  

If we are unable to obtain additional funding, we may have to reduce or discontinue our business operations.  

As  of  May  8,  2015,  we  had  cash  and  cash  equivalents  of  $2.1  million.  Therefore,  our  ability  to  continue  and  expand  our  operations  is 
highly  dependent  on  the  amount  of  cash  and  cash  equivalents  on  hand  combined  with  our  ability  to  raise  additional  capital  to  fund  future 
operations.  

Recently, we funded our operations through a short-term bridge financing and a preferred stock offering. We plan to raise additional funds 
through an equity or debt offering to cover general working capital needs and sales and marketing initiatives to expand our customer base and 
increase revenues. The Company currently anticipates that it will continue to raise additional capital to fund its short term operating expenses 
pursuant to private placements similar to private placements the Company has conducted in the past. The Company also anticipates seeking to 
raise up to $15 million pursuant to a public offering of its common stock and warrants to provide working capital and to support the Company’s 
anticipated  operations  and  development  plans.  If  we  are  not  able  to  raise  sufficient  funds  and  our  projected  revenues  and  cash-inflows  are 
reduced or delayed, we may not have sufficient capital to operate through the third quarter of our fiscal year 2016 or beyond. We are currently 
exploring various arrangements with respect to securing additional funding. However, there can be no assurance that any additional financing on 
commercially  reasonable  terms,  or  at  all,  will  be  available  when  needed.  The  inability  to  obtain  additional  capital  may  reduce  our  ability  to 
continue to conduct our business operations. Any additional equity financing will involve substantial dilution to our then existing stockholders. 
The uncertainties surrounding our future cash inflows have raised substantial doubt regarding our ability to continue as a going concern.  

Risks Related to Our Business  

Our agreements with global providers of shipping services may not result in a significant increase in our revenues or cash flow, soon or in 
the future.  

We  believe  that  establishing  strategic  alliances  with  global  providers  (integrators)  of  logistics  and  of  shipping  services,  such  as  our 
agreements  with FedEx,  DHL, and  UPS  can  drive growth in our  revenues, but  there is no certainty to  this view. We are seeking  to establish 
similar arrangements with other providers of international shipping services. We anticipate all such alliances will enable us to provide seamless, 
end-to-end shipping solutions to customers of our respective alliance partners and allow us to leverage the established relationships with those 
customers, but there is no guarantee this will happen.  

In January 2013, we entered into an agreement with FedEx, renewing FedEx’s right to, on a non-exclusive basis, promote, market and sell 
transportation of our shippers and our related value-added goods and services and providing FedEx with a non-exclusive license and right to use 
a  customized  version  of  our  Cryoportal™  software  platform  for  the  management  of  shipments  made  by  FedEx  customers.  In  June  2014,  we 
added DHL as our second major distribution partner, whereby DHL can offer our validated and comprehensive cryogenic solutions to its life 
sciences and healthcare customers on a  global basis.  In October 2014, we entered into an agreement with UPS related to our participation  in 
UPS’s efforts to expand its provision of cryogenic shipping services to the life sciences industry.  

Because our agreements with FedEx, DHL, and UPS do not contain any requirement that they use a minimum level of our services, there 

can be no assurance of any significant increase in our revenues or cash flows as a result of these strategic alliances.  

19 

   
   
   
   
   
   
   
   
   
   
   
   
  
Our agreements with providers of vaccines and stem cell-based therapies may not result in a significant increase in our revenues or cash 
flow.  

We believe that establishing strategic relationships with manufacturers and distributors of treatments for animals and humans, such as our 

agreements with Zoetis, Inc. and Liventa Bioscience, Inc., can drive growth in our revenues.  

In December 2012, we entered an agreement with what became Zoetis, Inc. (in January 2013, Pfizer spun off its animal health business 
into  Zoetis,  Inc.,  a  public  company)  pursuant  to  which  we  were  engaged  to  manage  frozen  shipments  of  a  key  poultry  vaccine  from  Zoetis’
production site in the United States. Over time, Zoetis has further expanded our role in providing them assistance in managing their cryogenic 
distribution of their vaccines and has become our largest customer.  

In February 2014,  we entered into an agreement with Liventa Bioscience, Inc. (“Liventa”) to act as its exclusive provider of cryogenic 
logistics  of  stem  cell  based  therapies  for  orthopedic  applications  based  on  meeting  minimum  performance  requirements  over  specified  time 
periods. Liventa intends to distribute its own line of therapies and to act as a distributor of other therapies to orthopedic health care providers that 
require controlled cryogenic temperatures. There is no assurance if or when Liventa will begin significant use of our services.  

While we anticipate growth in shipments by Zoetis under our management and that Liventa will be successful in its efforts to distribute 
cell based biologic materials to the orthopedic market, there can be no assurance of any significant increase in our revenues or cash flows as a 
result of these important alliances.  

We  will  have  difficulty  increasing  our  revenues  if  we  experience  delays,  difficulties  or  unanticipated  costs  in  establishing  the  sales, 
distribution and marketing capabilities necessary to successfully commercialize our solutions.  

We plan to improve our sales, distribution, and marketing capabilities in the Americas, Europe, and Asia. It will be expensive and time-
consuming for us to develop our global marketing and sales network and thus we intend to rely on our strategic alliances with FedEx, DHL, and 
UPS. We further intend to seek to enter into additional strategic alliances with international providers of shipping services to incorporate use of 
our  solutions  in  their  service  offerings.  We  may  not  be  able  to  provide  adequate  incentive  to  our  sales  force  or  to  establish  and  maintain 
favorable  distribution  and  marketing  collaborations  with  others  to  promote  our  solutions.  In  addition,  any  third  party  with  whom  we  have 
established a marketing and distribution relationship may not devote sufficient time to the marketing and sales of our solutions, thereby exposing 
us  to  potential  expenses  in  exiting  such  distribution  agreements.  We,  and  any  of  our  alliance  partners,  must  also  market  our  services  in 
compliance with federal, state, local and international laws relating to the provision of incentives and inducements. Violation of these laws can 
result in substantial penalties. Therefore, if we are unable to successfully motivate and expand our marketing and sales force and further develop 
our sales and marketing capabilities, or if our alliance partners fail to promote our solutions, we will have difficulty increasing our revenues and 
the revenue may not off-set the additional expense of expansion.  

Our ability to grow and compete in our industry will be hampered if we are unable to retain the continued service of our key professionals 
or to identify, hire and retain additional qualified professionals.  

A critical factor to our business is our ability to attract and retain qualified professionals including key employees and consultants. We are 
continually  at  risk  of  losing  current  professionals  or  being  unable  to  hire  additional  professionals  as  needed.  If  we  are  unable  to  attract  new 
qualified  employees, our  ability to grow  will  be  adversely affected.  If  we are unable  to  retain  current employees  or  strategic consultants, our 
financial condition and ability to maintain operations may be adversely affected.  

Sustainable future revenue growth is dependent on new solutions and services.  

Our future revenue stream depends to a large degree on our ability to bring new solutions and services to market on a timely basis. We 
must continue to make significant investments in research and development in order to continue to develop new solutions and services, enhance 
existing  solutions  and  services,  and  achieve  market  acceptance  of  such  solutions  and  services.  We  may  incur  problems  in  introducing  new 
solutions and services.  

The adoption cycle of our target customers tends to be very lengthy, which continues to adversely affect our ability to increase revenues 
quickly.  

We  offer  our  solutions  primarily  to  companies  in  the  life  sciences  industry.  These  companies  operate  within  a  heavily  regulated 
environment and as such, changing vendors and distribution practices typically require a number of steps, which may include the audit of our 
facilities, review of our procedures, qualifying us as a vendor, and performing test shipments. This process can take several months or longer to 
complete, involving multiple levels of approval, prior to a company fully adopting our Cryoport Express ® Solutions. The logistics management 
of many companies is decentralized adding to the time need to effect adaptation of our solutions. In addition, any such adoption may be on a 
gradual basis such that the  customer progressively ramps up use  of our Cryoport Express  ® Solutions following adoption.  The slow adoption 
process continues to adversely affect our ability to increase revenues.  

20 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
The loss of key members of our executive management team could adversely affect our business.  

Our  success  in  implementing  our  business  strategy  depends  largely  on  the  skills,  experience  and  performance  of  key  members  of  our 
executive management team and others in key management positions. The collective efforts of each of these persons working as a team will be 
critical to us as we continue to develop our technologies, tests and research and development and sales programs. As a result of the difficulty in 
locating qualified new management, the loss or incapacity of existing members of our executive management team could adversely affect our 
operations. If we were to lose one or more of these key employees, we could experience difficulties in finding qualified successors, competing 
effectively,  developing  our  technologies  and  implementing  our  business  strategy.  We  do  not  maintain  “key  person”  insurance  on  any  of  our 
employees.  

We are dependent on an outside party for the continued development and maintenance of our Cryoportal™ software.  

Our proprietary Cryoportal™ is a logistics platform software used by our customers, business partners and client care team to automate the 
entry of orders, prepare customs documentation and facilitate status and location monitoring of shipped orders while in transit. The continued 
development of the Cryoportal™ platform is contracted with an outside software development company. If this developer becomes unable or 
unwilling to continue work on scheduled projects, and an alternative software development company cannot be secured, we may not be able to 
implement  needed  enhancements  to  the  system.  Furthermore,  if  we  terminate  our  agreement  with  our  current  software  developer  and  cannot 
reach  an agreement  or  fail to  fulfill  an agreement  for  the  termination, it is possible we  could lose our  license  to use  this  software.  Failure  to 
proceed  with  enhancements  or  the  loss  of  our  license  for  the  system  would  adversely  affect  our  ability  to  generate  new  business  and  serve 
existing customers, resulting in a reduction in revenue.  

Our success depends, in part, on our ability to obtain patent protection for our solutions and business model, preserve our trade secrets, 
and operate without infringing the proprietary rights of others.  

Our policy is to seek to protect our proprietary position by, among other methods, filing United States patent applications related to our 
technology, inventions and improvements that are important to the development of our business. We have three issued U.S. patents; one pending 
patent,  and  one  recently  filed  provisional  patent  application,  all  relating  to  various  aspects  of  our  solutions  and  services.  Our  patents  or 
provisional patent application may be challenged, invalidated or circumvented in the future or the rights granted may not provide a competitive 
advantage. We intend to  vigorously  protect  and  defend our  intellectual  property. Costly  and time-consuming  litigation brought  by  us  may  be 
necessary  to enforce  our  patents  and  to protect  our  trade  secrets and  know-how,  or  to determine the  enforceability, scope  and  validity of  the 
proprietary rights of others.  

We also  rely  upon  trade  secrets,  technical know-how  and continuing technological  innovation to  develop  and  maintain our competitive 
position.  In  the  past  our  employees,  consultants,  advisors  and  suppliers  have  not  always  executed  confidentiality  agreements  and  invention 
assignment and work for hire agreements in connection with their employment, consulting, or advisory relationships. Consequently, we may not 
have adequate remedies available to us to protect our intellectual property should one of these parties attempt to use our trade secrets or refuse to 
assign any rights he or she may have in any intellectual property he or she developed for us. Additionally, our competitors may independently 
develop substantially equivalent proprietary information and techniques or otherwise gain access to our proprietary technology, or we may not 
be able to meaningfully protect our rights in unpatented proprietary technology.  

While we are not aware of any third party that is infringing any of our patents or trademarks nor do we believe that we are infringing on 
the patents or trademarks of any other person or organization, we cannot assure you that our current and potential competitors and other third 
parties have not filed (or in the future will not file) patent applications for (or have not received or in the future will not receive) patents or obtain 
additional proprietary rights that will prevent, limit or interfere with our ability to make, use or sell our solutions either in the United States or 
internationally.  Additionally,  we  may  face  assertions  of  claims  by  holders  of  patents  alleging  that  we  are  infringing  upon  their  patent  rights 
which claims are without merit, but may result in our incurring substantial costs of defense.  

If we were sued for product liability, we could face substantial liabilities that exceed our resources.  

The marketing, sale and use of our products could lead to the filing of product liability claims were someone to allege that our products 

failed to perform as designed. A product liability claim could result in substantial damages and be costly and time-consuming for us to defend.  

21 

   
   
   
   
   
   
   
   
   
   
   
  
Although we believe that our existing insurance is adequate, our insurers may fail to defend us or our insurance may not fully protect us 
from the financial impact of defending against product liability claims. Any product liability claim brought against us, with or without merit, 
could increase our insurance rates or prevent us from securing insurance coverage in the future. Additionally, any product liability lawsuit could 
damage our reputation, or cause current clinical partners and collaborators to terminate existing agreements and potential clinical partners to seek 
other partners, cause customers to terminate their relationship with us and potential customers to seek alternative solutions, any of which could 
impact our results of operations.  

Our  solutions  and  services  may  contain  errors  or  defects,  which  could  result  in  damage  to  our  reputation,  lost  revenues,  diverted 
development resources and increased service costs and litigation.  

Our solutions and services must meet stringent requirements and we must develop our services and solutions quickly to keep pace with the 
rapidly changing market. Solutions as sophisticated as ours could contain undetected errors or defects, especially when first introduced or when 
new  equipment  or  versions  of  our  software  are  released.  If  our  solutions  are  not  free  from  errors  or  defects,  we  may  incur  an  injury  to  our 
reputation,  lost  revenues,  diverted  development  resources,  increased  customer  service  and  support  costs,  and  litigation.  The  costs  incurred  in 
correcting any product errors or defects may be substantial and could adversely affect our business, results of operations and financial condition.  

If we experience manufacturing delays, interruptions in production, or delays in procurement of shippers manufactured by third parties, 
then we may experience customer dissatisfaction and our reputation could suffer.  

If we fail to produce enough shippers at our own manufacturing facility or at a third party manufacturing facility, or if we fail to complete 
our  shipper  recycling  processes  as  planned,  we  may  be  unable  to  deliver  shippers  to  our  customers  on  a  timely  basis,  which  could  lead  to 
customer dissatisfaction and could harm our reputation and ability to compete. We currently acquire various component parts for our shippers 
from  various  independent  manufacturers  in  the  United  States.  We  would  likely  experience  significant  delays  or  cessation  in  producing  our 
shippers if a labor strike, natural disaster or other supply disruption were to occur at any of our main suppliers. If we are unable to procure a 
component  from  one  of  our  manufacturers,  we  may  be  required  to  enter  into  arrangements  with  one  or  more  alternative  manufacturing 
companies, which may cause delays in producing our shippers. In addition, because we depend (in part) on third party manufacturers, our profit 
margins may be lower, which will make it more difficult for us to achieve profitability. To date, we have not experienced any material delay that 
has adversely impacted our operations. As our business develops it becomes more likely that such problems could arise.  

We expect to  base our equipment  and inventory  purchasing decisions  on our forecasts of customers’  demand, and  if our forecasts are 
inaccurate, our operating results could be materially harmed.  

As  our  customer  base  increases,  we  expect  to  need  to  purchase  additional  equipment  and  inventory.  Our  forecasts  will  be  based  on 
multiple assumptions, each of which may cause our estimates to be inaccurate, affecting our ability to provide products to our customers. When 
demand for our products increases significantly, we may not be able to meet demand on a timely basis, and we may need to expend a significant 
amount of time working with our customers to allocate limited supply and maintain positive customer relations, or we may incur additional costs 
in  order  to  rush  the  manufacture  and  delivery  of  additional  products.  If  we  underestimate  customers’  demand,  we  may  forego  revenue 
opportunities, lose  market  share and damage  our  customer  relationships.  Conversely,  if we  overestimate customer demand, we may purchase 
more equipment and inventory than we are able to use or sell at any given time or at all. As a result of our failure properly to estimate demand 
for  our  products,  we  could  have  excess  or  obsolete  equipment  and/or  inventory,  resulting  in  a  decline  in  the  value  of  our  equipment  and/or 
inventory, which would increase our costs of revenues and reduce our liquidity. Our failure to accurately manage our equipment purchases and 
inventory relative to demand would adversely affect our operating results.  

If  we  experience  delays  or  interruption  in  shipping  due  to  factors  outside  of  our  control,  such  disruption  could  lead  to  customer 
dissatisfaction and harm our reputation.  

We  rely  on  third  party  shipment  and  carrier  services  to  transport  our  shippers  containing  biological  material.  These  third  party  operations 
could be subject to natural disasters, adverse weather conditions, other business disruptions, and carrier error, which could cause delays in the 
delivery of our shippers, which in turn could cause serious harm to the biological material being shipped. As a result, any prolonged delay in 
shipment,  whether  due  to  technical  difficulties,  power  failures,  break-ins,  destruction  or  damage  to  carrier  facilities  as  a  result  of  a  natural 
disaster, fire, or any other reason, could result in damage to the contents of the shipper. If we are unable to cause the delivery of our shippers in a 
timely matter and without damage, this could also harm our operating results and our reputation, even if we are not at fault.  

22 

   
   
   
   
   
   
   
   
   
   
  
Our solutions and services may expose us to liability in excess of our current insurance coverage.  

Our solutions and services involve significant risks of liability, which may substantially exceed the revenues we derive from them. We 
cannot predict the magnitude of these potential liabilities. We currently maintain general liability insurance, with coverage in the amount of $1 
million per occurrence, subject to a $2 million annual limitation, and product liability insurance with a $1 million annual coverage limitation. 
Claims may be made against us that exceed these limits.  

Our liability policy is an “occurrence” based policy. Thus, our policy is complete when we purchased it and following cancellation of the 
policy  it  continues  to  provide  coverage  for  future  claims  based  on  conduct  that  took  place  during  the  policy  term.  Our  insurance  coverage, 
however, may not protect us against all liability because our policies typically have various exceptions to the claims covered and also require us 
to assume some costs of the claim even though a portion of the claim may be covered. In addition, if we expand into new markets, we may not 
be  aware  of  the  need  for,  or  be  able  to  obtain  insurance  coverage  for  such  activities  or,  if  insurance  is  obtained,  the  dollar  amount  of  any 
liabilities incurred could exceed our insurance coverage. A partially or completely uninsured claim, if successful and of significant magnitude, 
could have a material adverse effect on our business, financial condition and results of operations.  

If we use biological and hazardous materials in a manner that causes injury, we could be liable for damages.  

Our customers may ship potentially harmful biological materials in our dewars. We cannot eliminate the risk of accidental contamination 
or injury to employees or third parties from the use, storage, handling or disposal of these materials. In the event of contamination or injury, we 
could be held liable for any resulting damages, and any liability could exceed our resources or any applicable insurance coverage we may have. 
Additionally,  we  are  subject  to,  on  an  ongoing  basis,  federal,  state  and  local  laws  and  regulations  governing  the  use,  storage,  handling  and 
disposal of these materials and specified waste products. In the event of an accident, we could be held liable for damages.  

If we cannot compete effectively, we will lose business.  

Our services and solutions are positioned to be competitive in the life sciences cold-chain logistics market. While there are technological 
and marketing barriers to entry, we cannot guarantee that the barriers we are capable of producing will be sufficient to defend the market share 
we wish to gain against current and future competitors. Our principal competitive considerations in our market include:  

• 

• 

• 

• 

• 

• 

• 

• 

• 

• 

financial resources to allocate to proper marketing and an appropriate sales effort 

acceptance of our solutions model 

acceptance of our solutions including per use fee structures and other charges for services 

keeping up technologically with ongoing development of enhanced features and benefits 

reductions in the delivery costs of competitors’ solutions 

the ability to develop and maintain and expand strategic alliances 

establishing our brand name 

our ability to deliver our solutions to our customers when requested 

our timing of introductions of new solutions, and services 

financial resources to support working capital needs and required capital investments in infrastructure 

Current  and  prospective  competitors  have  substantially  greater  resources,  more  customers,  longer  operating  histories,  greater  name 
recognition and more established relationships in the industry. As a result, these competitors may be able to develop and expand their networks 
and  product  offerings  more  quickly,  devote  greater  resources  to  the  marketing  and  sale  of  their  solutions  and  adopt  more  aggressive  pricing 
policies. In addition, these competitors have entered and will likely continue to enter into business relationships to provide additional solutions 
competitive to those we provide or plan to provide .  

23 

   
   
   
   
   
   
   
   
   
   
  
We  may  acquire  other  businesses,  products  or  technologies  in  order  to  remain  competitive  in  our  market  and  our  business  could  be 
adversely affected as a result of any of these future acquisitions.  

We may make acquisitions of complementary businesses, products or technologies. If we identify any appropriate acquisition candidates, 
we  may  not  be  successful  in  negotiating  acceptable  terms  of  the  acquisition,  financing  the  acquisition,  or  integrating  the  acquired  business, 
products or technologies into our existing business and operations. Further, completing an acquisition and integrating an acquired business will 
significantly divert management time and resources. The diversion of management attention and any difficulties encountered in the transition 
and integration process could harm our business. If we consummate any significant acquisitions using stock or other securities as consideration, 
our shareholders' equity could be significantly diluted. If we make any significant acquisitions using cash consideration, we may be required to 
use a substantial portion of our available cash. Acquisition financing may not be available on favorable terms, if at all. In addition, we may be 
required  to  amortize  significant  amounts  of  other  intangible  assets  in  connection  with  future  acquisitions,  which  would  harm  our  operating 
results and financial condition.  

If we successfully develop products and/or services, but those products and/or services do not achieve and maintain market acceptance, 
our business will not be profitable.  

The degree of acceptance of our Cryoport Express ® Solutions or any future products or services by our current target markets, and any 
other  markets  to  which  we  attempt  to  sell  our  products  and  services,  and  our  profitability  and  growth  will  depend  on  a  number  of  factors 
including, among others:  

• 

• 

• 

• 

• 

• 

our shippers’ ability to perform and preserve the integrity of the materials shipped 

relative convenience and ease of use of our shipper and/or Cryoportal TM 

availability of alternative products 

pricing and cost effectiveness 

effectiveness of our or our collaborators’ sales and marketing strategy 

the adoption cycles of our targeted customers 

If any products or services we may develop do not achieve market acceptance, then we may not generate sufficient revenue to achieve or 

maintain profitability.  

In addition, even if our products and services achieve market acceptance, we may not be able to maintain that market acceptance over time 
if new products or services are introduced that are more favorably received than our products and services, are more cost effective, or render our 
products obsolete. Although we are not aware of any other treatments or methods currently being developed that would directly compete with 
the methods we employ,  there  can be no assurance  that  future developments  in  technology  will not make our technology  non-competitive  or 
obsolete,  or  significantly  reduce  our  operating  margins  or  the  demand  for  our  offerings,  or  otherwise  negatively  impact  our  ability  to  be 
profitable.  

We may not be able to compete with our competitors in the industry because many of them have greater resources than we do.  

We  expect  to  continue  to  experience  significant  and  increasing  levels  of  competition  in  the  future.  In  addition,  there  may  be  other 
companies which are currently developing competitive products and services or which may in the future develop technologies and products that 
are comparable, superior or less costly than our own. For example, some cryogenic equipment manufacturers with greater resources currently 
have  solutions  for  storing  and  transporting  cryogenic  liquid  and  gasses  and  may  develop  storage  solutions  that  compete  with  our  products. 
Additionally,  some  specialty  couriers  with  greater  resources  currently  provide  dry  ice  transportation  and  may  develop  other  products  in  the 
future, both of which compete with our products. A competitor that has greater resources than us may be able to bring its product to market faster 
than  we  can  and  offer  its  product  at  a  lower  price  than  us  to  establish  market  share.  We  may  not  be  able  to  successfully  compete  with  a 
competitor that has greater resources and such competition may adversely affect our business.  

24 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
Intellectual Property Risks Associated with Our Business  

Our success depends, in part, on our ability to obtain patent protection for our solutions and business model, preserve our trade secrets, and 
operate without infringing the proprietary rights of others.  

Our policy is to seek to protect our proprietary position by, among other methods, filing United States patent applications related to our 
technology, inventions and improvements that are important to the development of our business. We have three issued U.S. patents, one pending 
U.S. patent application, and one recently filed U.S. provisional patent application, all relating to various aspects of our solutions and services. 
Our  patents  or  patent  application  may  be  challenged,  invalidated  or  circumvented  in  the  future  or  the  rights  granted  may  not  provide  a 
competitive advantage. We intend to vigorously protect and defend our intellectual property. Costly and time-consuming litigation brought by us 
may be necessary to enforce our patents and to protect our trade secrets and know-how, or to determine the enforceability, scope and validity of 
the proprietary rights of others.  

We also  rely  upon  trade  secrets,  technical know-how  and continuing technological  innovation to  develop  and  maintain our competitive 
position.  In  the  past  our  employees,  consultants,  advisors  and  suppliers  have  not  always  executed  confidentiality  agreements  and  inventions 
assignment and work for hire agreements in connection with their employment, consulting, or advisory relationships. Consequently, we may not 
have adequate remedies available to us to protect our intellectual property should one of these parties attempt to use our trade secrets or refuse to 
assign any rights he or she may have in any intellectual property he or she developed for us. Additionally, our competitors may independently 
develop substantially equivalent proprietary information and techniques or otherwise gain access to our proprietary technology, or we may not 
be able to meaningfully protect our rights in unpatented proprietary technology.  

While we are not aware of any third party that is infringing any of our patents or trademarks nor do we believe that we are infringing on 
the patents or  trademarks of any other person  or organization,  we cannot guarantee that our current and potential competitors and other third 
parties have not filed (or in the future will not file) patent applications for (or have not received or in the future will not receive) patents or obtain 
additional proprietary rights that will prevent, limit or interfere with our ability to make, use or sell our solutions either in the United States or 
internationally.  Additionally,  we  may  face  assertions  of  claims  by  holders  of  patents  alleging  that  we  are  infringing  upon  their  patent  rights, 
which claims may be without merit, but may nonetheless result in our incurring substantial costs of defense.  

We are dependent on a third party for the continued development and maintenance of our Cryoportal™ software.  

Our proprietary Cryoportal™ is a logistics platform software used by our customers, business partners and client care team to automate the 
entry of orders, prepare customs documentation and facilitate status and location monitoring of shipped orders while in transit. The continued 
development of the Cryoportal™ platform is contracted with an outside software development company. If this developer becomes unable or 
unwilling to continue work on scheduled projects, and an alternative software development company cannot be secured, we may not be able to 
implement  needed  enhancements  to  the  system.  Furthermore,  if  we  terminate  our  agreement  with  our  current  software  developer  and  cannot 
reach  an agreement  or  fail to  fulfill  an agreement  for  the  termination, it is possible we  could lose our  license  to use  this  software.  Failure  to 
proceed  with  enhancements  or  the  loss  of  our  license  for  the  system  would  adversely  affect  our  ability  to  generate  new  business  and  serve 
existing customers, resulting in a reduction in revenue.  

Our customers could also become the target of litigation relating to the patent and other intellectual property rights of others.  

Any  litigation  relating  to  the  intellectual  property  rights  of  others  could  trigger  technical  support  and  indemnification  obligations  in 
licenses or customer agreements that we may enter into. These obligations could result in substantial expenses, including the payment by us of 
costs and damages relating to claims of intellectual property infringement. In addition to the time and expense required for us to provide support 
or indemnification to our customers, any such litigation could disrupt the businesses of our customers, which in turn could hurt our relationships 
with such customers and cause the sale of our products to decrease. No assurance can be given that claims for indemnification will not be made, 
or that if made, such claims would not have a material adverse effect on our business, operating results or financial conditions.  

Our Cryoportal™ software platform may be subject to intentional disruption that could adversely impact our reputation and future revenues. 

We have implemented our Cryoportal™ software platform which is used by our customers and business partners to automate the entry of 
orders, prepare customs documentation and facilitate status and location monitoring of shipped orders while in transit. Although we believe we 
have  sufficient  controls  in  place  to  prevent  intentional  disruptions,  we  could  be  a  target  of  cyber-attacks  specifically  designed  to  impede  the 
performance of the Cryoportal™ software platform. Similarly, experienced computer programmers may attempt to penetrate our Cryoportal™ 
software  platform  in  an  effort  to  search  for  and  misappropriate  proprietary  or  confidential  information  or  cause  interruptions  of  our  services. 
Because the techniques used by such computer programmers to access or sabotage networks change frequently and may not be recognized until 
launched against a target, we may be unable to anticipate these techniques. Our activities could be adversely affected and our reputation, brand 
and future sales could be harmed if such intentionally disruptive efforts were successful.  

25 

   
   
   
   
   
   
   
   
   
    
   
   
  
Regulatory Risks Relating to Our Business  

Complying with certain regulations that apply to shipments using our solutions can limit our activities and increase our cost of operations.  

Shipments using our solutions and services are subject to various regulations in the various countries in which we operate. For example, 
shipments  using  our  solutions  may  be  required  to  comply  with  the  shipping  requirements  promulgated  by  the  Centers  for  Disease  Control 
(“CDC”), the Occupational Safety and Health Organization (“OSHA”), the Department of Transportation (“DOT”) as well as rules established 
by the IATA and the ICAO. Additionally, our data logger may be subject to regulation and certification by the Food and Drug Administration 
(“FDA”), Federal Communications Commission (“FCC”), and the Federal Aviation Administration (“FAA”). We will need to ensure that our 
solutions and services comply with relevant rules and regulations to make our solutions and services marketable, and in some cases compliance 
is difficult to determine. Significant changes in such regulations could require costly changes to our solutions and services or prevent use of our 
shippers for an extended period of time while we seek to comply with changed regulations. If we are unable to comply with any of these rules or 
regulations or fail to obtain any required approvals, our ability to market our solutions and services may be adversely affected. In addition, even 
if  we  are  able  to  comply  with  these  rules  and  regulations,  compliance  can  result  in  increased  costs.  In  either  event,  our  financial  results  and 
condition may be adversely affected. We depend on our business partners and unrelated and frequently unknown third party agents in foreign 
countries to act on our behalf to complete the importation process and to make delivery of our shippers to the final user. The failure of these third 
parties to perform their duties could result in damage to the contents of the shipper resulting in customer dissatisfaction or liability to us, even if 
we are not at fault.  

Risks Relating to Our Current Financing Arrangements  

Certain of our existing stockholders own and have the right to acquire a substantial number of shares of common stock.  

As of May 8, 2015, our directors, executive officers and beneficial owners of 5% or more of our outstanding common stock beneficially 
owned  1,208,251  shares  of  common  stock  (without  regard  to  beneficial  ownership  limitations  contained  in  certain  warrants)  assuming  their 
exercise of all outstanding warrants and options that are exercisable within 60 days of May 8, 2015 or approximately 20.1% of our outstanding 
common stock. Of these shares of common stock, 287,469 shares, or approximately 5.4% of our common stock, will be beneficially owned by 
Cranshire  Capital  Master  Fund.  As  such,  the  concentration  of  beneficial ownership of  our  common  stock  may have  the  effect  of  delaying  or 
preventing a change in control of Cryoport and may adversely affect the voting or other rights of other holders of our common stock.  

The sale of substantial shares of our common stock may depress our stock price.  

As of May 8, 2015, there were 5,025,577 shares of our common stock outstanding. Substantially all of these shares of common stock are 
eligible for trading in the public market. The market price of our common stock may decline if our stockholders sell a large number of shares of 
our common stock in the public market, or the market perceives that such sales may occur. We could also issue up to 8,993,495 shares of our 
common stock  including shares to  be  issued  upon the  exercise of  outstanding  warrants  and  options  or  reserved for future  issuance  under our 
stock incentive plans, as further described in the following table:  

Common stock issuable upon conversion of outstanding preferred stock 
Common stock issuable upon exercise of outstanding warrants 
Common stock issuable upon exercise of outstanding options or reserved for future incentive 

awards under our stock incentive plans 

Total 

26 

Number of  
Shares of  
Common Stock  
Issuable or  
Reserved for  
Issuance 

1,541,148   
5,475,806   

1,976,541   

8,993,495   

   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
    
    
    
  
    
    
    
Of the total preferred stock, options and warrants outstanding as of March 31, 2015, preferred stock, options and warrants exercisable for 
an aggregate of 2,397,712 shares of common stock would be considered dilutive to the value of our stockholders’ interest in Cryoport because 
we would receive upon exercise of such options and warrants an amount per share that is less than the market price of our common stock on 
March 31, 2015.  

Our stock price has been and will likely continue to be volatile.  

The market price of our common stock has been highly volatile and could fluctuate widely in price in response to various factors, many of 

which are beyond our control, including, but not limited to:  

• 

• 

• 

• 

• 

• 

• 

• 

• 

technological innovations or new solutions and services by us or our competitors 

additions or departures of key personnel 

sales of our common stock 

our ability to execute our business plan 

our operating results being below expectations 

loss of any strategic relationship 

industry developments 

economic and other external factors 

period-to-period fluctuations in our financial results 

In addition, the securities markets have from time to time experienced significant price and volume fluctuations that are unrelated to the 
operating  performance  of  particular  companies.  These  market  fluctuations  may  also  materially  and  adversely  affect  the  market  price  of  our 
common stock and warrants.  

In addition, we completed a 1-for-12 reverse stock split in May 2015. There can be no assurance that the reverse stock split will have the 
anticipated benefits. For instance, there can be no assurance that the market price per share of our common stock after the reverse stock split will 
rise in proportion to the reduction in the number of shares of our common stock outstanding before the reverse stock split, or that the reverse 
stock split will result in a market price per share that will attract brokers and investors who do not trade in lower priced stocks.  

Additionally, the liquidity of our common stock could be adversely affected by the reduced number of shares resulting from the reverse 
stock split, which, in turn, could result in greater volatility in the price per share of our common stock. The potential volatility in the price per 
share  of  our  common  stock  may  also  make  short-selling  more  attractive,  which  could  put  additional  downward  pressure  on  the  price  of  our 
common stock.  

Furthermore, the reverse stock split may result in some shareholders owning “odd lots” of less than one hundred shares of our common 
stock on a post-split basis. Odd lots may be more difficult to sell, or require greater transaction costs per share to sell, than shares in “round lots”
of even multiples of one hundred shares  

If equity research analysts do not publish research or reports about our business or if they issue unfavorable commentary or downgrade 
our common stock and warrants, the price of our common stock and warrants could decline.  

The trading market for our common stock and warrants relies in part on the research and reports that equity research analysts publish about 
us and our business. We do not control these analysts. The price of our common stock and warrants could decline if one or more equity analyst 
downgrades our  stock or  if analysts downgrade  our stock  or  issue  other unfavorable  commentary  or cease publishing  reports about  us or our 
business.  

We have not paid dividends on our common stock in the past and do not expect to pay dividends in the foreseeable future. Any return on 
investment may be limited to the value of our common stock.  

We  have  never  paid  cash  dividends  on  our  common  stock  and  do  not  anticipate  paying  cash  dividends  in  the  foreseeable  future.  The 
payment of dividends on our common stock will depend on our earnings, financial condition and other business and economic factors affecting 
us at such time as the Board of Directors may consider the payment of any such dividends. If we do not pay dividends, our common stock may 
be less valuable because a return on your investment will only occur if the price of our common stock appreciates.  

27 

   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
We need additional capital, and the sale of additional shares of common stock or other equity securities could result in additional dilution 
to our stockholders.  

Our  current  cash  and  cash  equivalents  and  anticipated  cash  flow  from  operations  are  insufficient  to  meet  our  cash  needs.  We  require 
additional cash resources to fund our operations and may require additional funds in the future due to changed business conditions or other future 
developments, including  any  investments  or  acquisitions  we  may  decide  to  pursue. The  sale  of  additional  equity  securities, or  debt  securities 
convertible into equity securities, could result in additional dilution to our stockholders. The incurrence of indebtedness would result in increased 
debt service obligations and could result in operating and financing covenants that would restrict our operations.  

Our Articles of Incorporation allows our Board of Directors to issue up to 2,500,000 shares of “blank check” preferred stock.  

Our  Articles  of  Incorporation  allows  our  Board  of  Directors  to  issue  up  to  2,500,000  shares  of  “blank  check”  preferred  stock,  without 
action by our stockholders. We have designated 800,000 shares as Class A Convertible Preferred Stock, of which 454,750 shares are issued and 
outstanding at March 31, 2015 and 585,000 shares as Class B Convertible Preferred Stock, of which 161,709 shares are issued and outstanding 
as of March 31, 2015. Accordingly, the Board of Directors will have discretion to issue up to 1,115,000 shares on terms determined by them. 
Without  limiting  the  foregoing,  (i)  such  shares  of  preferred  stock  could  have  liquidation  rights  that  are  senior  to  the  liquidation  preference 
applicable  to our  common  stock and  Preferred Stock, (ii)  such  shares  of preferred stock could have  voting or conversion rights, which could 
adversely  affect  the  voting  power  of  the  holders  of  our  common  stock  and  Preferred  Stock  and  (iii)  the  ownership  interest  of  holders  of  our 
common stock will be diluted following the issuance of any such shares of preferred stock. In addition the issuance of such shares of blank check 
preferred stock could have the effect of discouraging, delaying or preventing a change of control of our Company.  

Provisions  in  our  bylaws  and  Nevada  law  might  discourage,  delay  or  prevent  a  change  of  control  of  our  Company  or  changes  in  our 
management and, as a result, may depress the trading price of our common stock.  

Provisions  of  our  bylaws  and  Nevada  law  may  discourage,  delay  or  prevent  a  merger,  acquisition  or  other  change  in  control  that 
stockholders may consider favorable, including transactions in which you might otherwise receive a premium for your shares of our common 
stock. The relevant bylaw provisions may also prevent or frustrate attempts by our stockholders to replace or remove our management. These 
provisions include advance notice requirements for stockholder proposals and nominations, and the ability of our Board of Directors to make, 
alter or repeal our bylaws.  

Absent approval of our Board of Directors, our bylaws may only be amended or repealed by the affirmative vote of the holders of at least a 

majority of our outstanding shares of capital stock entitled to vote.  

In  addition,  Section 78.438  of  the  Nevada  Revised  Statutes  prohibits  a  publicly-held  Nevada  corporation  from  engaging  in  a  business 
combination with an interested stockholder (generally defined as a person which together with its affiliates owns, or within the last three years 
has  owned,  10%  of  our  voting  stock,  for  a  period  of  three  years  after  the  date  of  the  transaction  in  which  the  person  became  an  interested 
stockholder) unless the business combination is approved in a prescribed manner.  

The existence of the foregoing provisions and other potential anti-takeover measures could limit the price that investors might be willing to 
pay in the future for shares of our common stock. They could also deter potential acquirers of our Company, thereby reducing the likelihood that 
you could receive a premium for your common stock in an acquisition.  

Even  though  we  are  not  incorporated  in  California,  we  may  become  subject  to  a  number  of  provisions  of  the  California  General 
Corporation Law.  

Section 2115(b) of the California Corporations Code imposes certain requirements of California corporate law on corporations organized 
outside California that, in general, are doing more than 50% of their business in California and have more than 50% of their outstanding voting 
securities held of record by persons residing in California. While we are not currently subject to Section 2115(b), we may become subject to it in 
the future.  

The following summarizes some of the principal differences which would apply if we become subject to Section 2115(b).  

Under  both  Nevada  and  California  law,  cumulative  voting  for  the  election  of  directors  is  permitted.  However,  under  Nevada  law 
cumulative voting must be expressly authorized in the Articles of Incorporation and our Amended and Restated Articles of Incorporation do not 
authorize  cumulative  voting.  If  we  become  subject  to  Section 2115(b),  we  may  be  required  to  permit  cumulative  voting  if  any  stockholder 
properly requests to cumulate his or her votes.  

28 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
Under Nevada law, directors may be removed by the stockholders only by the vote of two-thirds of the voting power of the issued and 
outstanding stock entitled to vote. However, California law permits the removal of directors by the vote of only a majority of the outstanding 
shares entitled to vote. If we become subject to Section 2115(b), the removal of a director may be accomplished by a majority vote, rather than a 
vote of two-thirds, of the stockholders entitled to vote.  

Under  California  law,  the  corporation  must  take  certain  steps  to  be  allowed  to  provide  for  greater  indemnification  of  its  officers  and 
directors than is provided in the California Corporation Code. If we become subject to Section 2115(b), our ability to indemnify our officers and 
directors, to the extent permitted in our Articles of Incorporation, Bylaws and under Nevada law, may be limited by California law.  

Nevada law permits distributions to stockholders as long as, after the distribution, (i) the corporation would be able to pay its debts as they 
become due and (ii) the corporation’s total assets are at least equal to its liabilities and preferential dissolution obligations. Under California law, 
distributions may be made to stockholders as long as the corporation would be able to pay its debts as they mature and either (i) the corporation’s 
retained earnings equal or exceed the amount of the proposed distributions, or (ii) after the distributions, the corporation’s tangible assets are at 
least 125% of its liabilities and the corporation’s current assets are at least equal to its current liabilities (or, 125% of its current liabilities if the 
corporation’s average operating income for the two most recently completed fiscal years was less than the average of the interest expense of the 
corporation for those fiscal years). If we become subject to Section 2115(b), we will have to satisfy more stringent financial requirements to be 
able  to  pay  dividends  to  our  stockholders.  Additionally,  stockholders  may  be  liable  to  the  corporation  if  we  pay  dividends  in  violation  of 
California law.  

California  law  permits  a  corporation  to  provide  “supermajority  vote”  provisions  in  its  Articles  of  Incorporation,  which  would  require 
specific actions to obtain greater than a majority of the votes, but not more than 66 2 / 3 percent. Nevada law does not permit supermajority vote 
provisions. If we become subject to Section 2115(b), it is possible that our stockholders would vote to amend our Articles of Incorporation and 
require a supermajority vote for us to take specific actions.  

Under  California  law,  in  a  disposition  of  substantially  of  all  the  corporation’s  assets,  if  the  acquiring  party  is  in  control  of  or  under 
common control with the disposing corporation, the principal terms of the sale must be approved by 90 percent of the stockholders. Although 
Nevada law does contain certain rules governing interested stockholder business combinations, it does not require similar stockholder approval. 
If we become subject to Section 2115(b), we may have to obtain the vote of a greater percentage of the stockholders to approve a sale of our 
assets to a party that is in control of, or under common control with, us.  

California  law  places  certain  additional  approval  rights  in  connection  with  a  merger  if  all  of  the  shares  of  each  class  or  series  of  a 
corporation are not treated equally or if the surviving or parent party to a merger represents more than 50 percent of the voting power of the other 
corporation prior to the merger. Nevada law does not require such approval. If we become subject to Section 2115(b), we may have to obtain the 
vote of a greater percentage of the stockholders to approve a merger that treats shares of a class or series differently or where a surviving or 
parent party to the merger represents more than 50% of the voting power of the other corporation prior to the merger.  

California law requires the vote of each class to approve a reorganization or a conversion of a corporation into another entity. Nevada law 
does not require a separate vote for each class. If we become subject to Section 2115(b), we may have to obtain the approval of each class if we 
desire to reorganize or convert into another type of entity.  

California  law  provides  greater  dissenters’  rights  to  stockholders  than  Nevada  law.  If  we  become  subject  to  Section 2115(b),  more 

stockholders may be entitled to dissenters’ rights, which may limit our ability to merge with another entity or reorganize.  

Our stock is deemed to be penny stock.  

Our stock is currently traded on the OTCQB, operated by the OTC Markets Group, Inc., and is subject to the “penny stock rules” adopted 
pursuant to Section 15(g) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). The penny stock rules apply to companies 
not  listed  on  a  national  exchange  whose  common  stock  trades  at  less  than  $5.00  per  share  or  which  have  tangible  net  worth  of  less  than 
$5,000,000 ($2,000,000 if the company has been operating for three or more years). Such rules require, among other things, that brokers who 
trade “penny stock” to persons other than “established customers” complete certain documentation, make suitability inquiries of investors and 
provide investors with certain information concerning trading in the security, including a risk disclosure document and quote information under 
certain circumstances. Penny stocks sold in violation of the applicable rules may entitle the buyer of the stock to rescind the sale and receive a 
full refund from the broker.  

29 

   
   
   
   
   
   
   
   
   
   
   
  
Many brokers have decided not to trade “penny stock” because of the requirements of the penny stock rules and, as a result, the number of 
broker-dealers willing to act as market makers in such securities is limited. In the event that we remain subject to the “penny stock rules” for any 
significant period, there may develop an adverse impact on the market, if any, for our securities. Because our securities are subject to the “penny 
stock  rules,”  investors  will  find  it  more  difficult  to  dispose  of  our  securities.  Further,  for  companies  whose  securities  are  traded  in  the  OTC 
Bulletin  Board,  it  is  more  difficult:  (i)  to  obtain  accurate  quotations,  (ii)  to  obtain  coverage  for  significant  news  events  because  major  wire 
services, such as the Dow Jones News Service, generally do not publish press releases about such companies, and (iii) to obtain needed capital.  

 If  we  fail  to  maintain  an  effective  system  of  internal  control  over  financial  reporting,  we  may  not  be  able  to  accurately  report  our 
financial results, and current and potential stockholders may lose confidence in our financial reporting.  

We are required by the SEC to establish and maintain adequate internal control over financial reporting that provides reasonable assurance 
regarding the reliability of our financial reporting and the preparation of financial statements in accordance with generally accepted accounting 
principles. We are likewise required, on a quarterly basis, to evaluate the effectiveness of our internal controls and to disclose any changes and 
material weaknesses in those internal controls.  

As described in Item 9A of this Annual Report on Form 10-K for the year ended March 31, 2015, no material weaknesses were identified 

and we determined that our internal control over financial reporting was effective as of March 31, 2015.  

Any failure to maintain such internal controls in the future could adversely impact our ability to report our financial results on a timely and 
accurate basis. If our financial statements are not accurate, investors may not have a complete understanding of our operations. Likewise, if our 
financial statements are not filed on a timely basis as required by the SEC and the OTC Bulletin Board, we could face severe consequences from 
those authorities. In either case, there could result a material adverse effect on our business. Inferior internal controls could also cause investors 
to lose confidence in our reported financial information, which could have a negative effect on the trading price of our stock.  

Our publicly-filed SEC reports are reviewed by the SEC from time to time and any significant changes required as a result of any such 
review may result in material liability to us and have a material adverse impact on the trading price of our common stock.  

The reports of publicly-traded companies are subject to review by the SEC from time to time for the purpose of assisting companies in 
complying with applicable disclosure requirements and to enhance the overall effectiveness of companies’ public filings, and reviews of such 
reports are now required at least every three years under the Sarbanes-Oxley Act of 2002. SEC reviews may be initiated at any time, and we 
could  be  required  to  modify  or  reformulate  information  contained  in  prior  filings  as  a  result  of  an  SEC  review.  Any  modification  or 
reformulation of information contained in such reports could be significant and could result in material liability to us and have a material adverse 
impact on the trading price of our common stock.  

The requirements of being a U.S. public company may strain our resources and divert management’s attention.  

As a U.S. public company, we are subject to the reporting requirements of the Exchange Act, the Sarbanes-Oxley Act, the Dodd-Frank 
Act, certain listing requirements, and other applicable securities rules and regulations. Compliance with these rules and regulations will increase 
our legal and financial compliance costs, make some activities more difficult, time-consuming, or costly, and increase demand on our systems 
and resources. The Exchange Act requires, among other things, that we file annual and current reports with respect to our business and operating 
results.  As  a  result  of  disclosure  of  information  in  this  prospectus  and  in  filings  required  of  a  public  company,  our  business  and  financial 
condition is more visible, which we believe may result in threatened or actual litigation, including by competitors and other third parties. If such 
claims are successful, our business and operating results could be harmed, and even if the claims do not result in litigation or are resolved in our 
favor, these claims, and the time and resources necessary to resolve them, could divert resources of our management and harm our business and 
operating results.  

ITEM 1B.   Unresolved Staff Comments  

Not applicable.  

ITEM 2.   Properties  

We  do  not  own  real  property.  We  currently  lease  one  facility,  with  approximately  12,000  square  feet  of  corporate,  research  and 
development,  and  warehouse  facilities,  located  in  Lake  Forest,  California  under  an  operating  lease  expiring  June 30,  2015,  which  we  do  not 
intend to renew. In May 2015, we amended the lease to convert to a month-to-month basis, commencing July 1, 2015. The base rent will be 
$9,500  and  either  party  will  have  the  right  to  cancel  this  month-to-month  agreement  by  giving  the  other  party  a  minimum  of  a  90-day  prior 
written notice. We are currently exploring other facilities to meet our growing demands. The lease agreement contains certain scheduled rent 
increases, which are accounted for on a straight-line basis.  

30 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
The Company currently makes base lease payments of approximately $8,900 per month, due at the beginning of each month. We believe 
that these facilities are adequate, suitable and of sufficient capacity to support our immediate needs. Additional space may be required, however, 
as we expand our research and development, manufacturing and selling and marketing activities.  

ITEM 3.   Legal Proceedings  

In the ordinary course of business, we are at times subject to various legal proceedings and disputes, including product liability claims. We 

currently are not aware of any such legal proceedings or claim that we believe will have, individually or in the aggregate, a material adverse 
effect on our business, operating results or cash flows. It is our practice to accrue for open claims based on our historical experience and 
available insurance coverage.  

ITEM 4.   Mine Safety Disclosures  

Not applicable  

PART II  

ITEM 5.   Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities  

Common Stock  

As of May 8, 2015 there were 5,025,577 shares of common stock outstanding and 228 stockholders of record. On May 8, 2015, the closing 
sale price of our common stock was $7.68 per share. Cryoport completed a 1-for-12 reverse stock split in May 2015. All common stock and per-
share information included in this Annual Report on Form 10-K reflect such reverse stock split.  

Market Information  

Our common stock is traded on the OTCQB, operated by the OTC Markets Group, Inc. under the symbol “CYRX”. The high and low 

closing sale prices of our common stock reported by OTCQB during each quarter ended March 31, 2015 and 2014 were as follows:    

Year 2015: 

Fourth Quarter Ended March 31, 2015 
Third Quarter Ended December 31, 2014 
Second Quarter Ended September 30, 2014 
First Quarter Ended June 30, 2014 

Year 2014: 

Fourth Quarter Ended March 31, 2014 
Third Quarter Ended December 31, 2013 
Second Quarter Ended September 30, 2013 
First Quarter Ended June 30, 2013 

Dividends  

High  

Low  

  $ 
  $ 
  $ 
  $ 

  $ 
  $ 
  $ 
  $ 

8.64     $ 
5.76     $ 
5.88     $ 
6.36     $ 

6.84     $ 
6.60     $ 
6.24     $ 
6.72     $ 

4.56   
4.32   
4.80   
4.20   

4.08   
3.60   
2.76   
1.92   

No  dividends  on  common  stock  have  been  declared  or  paid  by  the  Company.  As  of  March  31,  2015,  the  Company  had  cumulative, 
undeclared  dividends  that  have  not  been  accrued  related  to  its  outstanding  preferred  stock  of  $305,300.  The  Company  intends  to  employ  all 
available funds for the development of its business and, accordingly, does not intend to pay any cash dividends in the foreseeable future.  

Securities Authorized for Issuance Under Equity Compensation  

The information included under Item 12 of Part III of this Annual Report is hereby incorporated by reference into this Item 5 of Part II of 

this Annual Report.  

Recent Sale of Unregistered Securities  

The following is a summary of transactions by the Company during period covered by this report involving the issuance and sale of the 
Company’s securities that were not registered under the Securities Act of 1933, as amended (the “Securities Act”) and that have not previously 
been  included  in  a  Quarterly  Report  on  Form  10-Q  or  in  a  Current  Report  on  Form  8-K.  All  securities  sold  by  the  Company  were  sold  to 
individuals, trusts or others who were accredited investors as defined under Regulation D under the Securities Act.  

31 

    
  
  
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
    
  
    
        
    
  
    
        
    
    
        
    
Between February 19, 2015 and March 31, 2015, the Company conducted a private placement pursuant to which the Company sold and 
issued  an  aggregate  of  161,709  shares  of  Class  B  Convertible  Preferred  Stock  and  warrants  to  purchase  107,806  shares  of  common  stock  at 
$12.00 per unit, for gross proceeds of $1.9 million. Emergent Financial Group, Inc. served as the Company’s placement agent in this transaction 
and received a commission of 10% and a non-accountable finance fee of 3% of the aggregate gross proceeds received from the investors, plus 
reimbursement  of  up  to  $5,000  of  legal  expenses.  Emergent  Financial  Group,  Inc.  will  also  be  issued  a  warrant  to  purchase  0.25  shares  of 
common stock at an exercise price of $6.00 per share for each share of Class B Convertible Preferred Stock issued in this transaction.  

In January 2015, we issued 1,667 shares of restricted common stock to a consultant in exchange for services. The Company recognized 

$8,400 in expense related to these shares for the year ended March 31, 2015.  

Between December 2014 and February 2015, we issued 2014 Series Secured Promissory Notes (the “7% Bridge Notes”) in the aggregate 
original principal amount of $915,000. The 7% Bridge Notes accrue interest at a rate of 7% per annum. All principal and interest is due on July 
1, 2015 unless we elect to extend the maturity date to January 1, 2016 by providing written notice to the note holders and a warrant to purchase a 
number of shares of common stock equal to (a) the then outstanding principal balance of the note, divided by (b) $6.00 multiplied by 125%. In 
connection with the issuance of the notes, we issued the note holders warrants to purchase 190,625 shares of common stock at an exercise price 
of $6.00 per share. The warrants are exercisable on May 31, 2015 and expire on November 20, 2021. All unpaid principal and interest was repaid 
in April 2015.  

In February 2015, the Company conducted a private placement pursuant to which the Company sold and issued an aggregate of 11,862 
shares of Class A Convertible Preferred Stock and warrants to purchase 7,908 shares of common stock, at $12.00 per unit, for gross proceeds of 
$142,400. Emergent Financial Group, Inc. served as the Company’s placement agent in this transaction and received a commission of 3% and a 
non-accountable finance fee of 1% of such proceeds, and with respect to gross proceeds received from all other investors, a commission of 10% 
and a non-accountable finance fee of 3% of the aggregate gross proceeds received from such investors, plus reimbursement of legal expenses of 
up to $40,000. Emergent Financial Group, Inc. will also be issued a warrant to purchase 0.25 shares of common stock at an exercise price of 
$6.00 per share for each share of Class A Convertible Preferred Stock issued in this transaction.  

The issuance of the securities of the Company in the above transaction were deemed to be exempt from registration under the Securities 
Act by virtue of Section 4(2) thereof or Regulation D promulgated there under, as a transaction by an issuer not involving a public offering. With 
respect to the transaction listed above, no general solicitation was made by either the Company or any person acting on the Company’s behalf; 
the securities sold are subject to transfer restrictions; and the certificates for the shares contain an appropriate legend stating that such securities 
have not been registered under the Securities Act and may not be offered or sold absent registration or pursuant to an exemption therefrom.  

ITEM 6.   Selected Financial Data  

The following selected financial data has been derived from audited consolidated financial statements of the Company for each of the five 
years  in  the  period  ended  March  31,  2015.  You  should  read  the  following  financial  information  together  with  the  information  under 
“Management’s  Discussion  and  Analysis  of  Financial  Condition  and  Results  of  Operations”  and  our  consolidated  financial  statements  and 
related  notes  included  elsewhere  in  this  annual  report.  The  information  set  forth  below  is  not  necessarily  indicative  of  our  future  financial 
condition or results of operations.  

Statement of Operations Data:    

2015    

Years ended March 31,  
2013    

2014    
(In thousands, except per share data) 

2012   

Revenues 
Cost of revenues 
Gross margin (loss) 

Selling, general and administrative 
Research and development 

Loss from operations 
Debt conversion expense 
Interest income 
Interest expense 

  $ 

3,935     $ 
2,766       
1,169       

6,409       
353       
(5,593 )     
—      
—      
(1,428 )     

32 

2,660     $ 
2,223       
437       

5,106       
409       
(5,078 )     
(13,714 )     
—      
(784 )     

1,101     $ 
1,588       
(487 )     

5,412       
425       
(6,324 )     
—      
—      
(72 )     

556     $ 
1,392       
(836 )     

6,106       
492       
(7,434 )     
—      
12       
(528 )     

2011   

476   
1,303   
(827 ) 

4,321   
449   
(5,597 ) 
—  
16   
(619 ) 

   
   
   
   
   
   
   
   
   
  
  
  
  
  
    
    
    
    
  
  
  
  
    
    
  
    
        
        
        
        
    
    
    
    
    
    
    
Statement of Operations Data:   

2015 

2014 

Years ended March 31, 
2013 
(In thousands, except per share data) 

2012 

Change in fair value of derivative liabilities 
Other expense, net 

Loss before provision for income taxes 
Provision for income taxes 

Net loss 
Preferred stock beneficial conversion charge 
Undeclared cumulative preferred dividends 
Net loss attributable to common stockholders 
Net loss per share attributable to common 
stockholders — basic and diluted 

Balance Sheet Data: 

Cash and cash equivalents 
Working capital (deficit) 
Total assets 
Convertible notes and accrued interest, net 
Long term obligations, less current portion 
Total stockholders’ equity (deficit) 

  $ 

  $ 

  $ 

—      
(4 )     
(7,025 )     
2       
(7,027 )     
(4,864 )     
(306 )     
(12,197 )   $ 

21       
(8 )     
(19,563 )     
2       
(19,565 )     
—      
—      
(19,565 )   $ 

16       
—      
(6,380 )     
2       
(6,382 )     
—      
—      
(6,382 )   $ 

119       
—      
(7,831 )     
2       
(7,833 )     
—      
—      
(7,833 )   $ 

2011 

50   
—  
(6,150 ) 
2   
(6,152 ) 
—  
—  
(6,152 ) 

(2.44 )   $ 

(4.81 )   $ 

(2.03 )   $ 

(3.24 )   $ 

(5.55 ) 

2015 

2014 

As of March 31, 
2013 
(In thousands) 

2012 

2011 

1,405     $ 
(835 )     
2,607       
—      
26       
(416 )     

370     $ 
(2,903 )     
1,710       
1,622       
—      
(2,304 )     

563     $ 
(1,539 )     
1,756       
1,304       
1,322       
(2,063 )     

4,618     $ 
4,024       
6,214       
338       
1,375       
3,730       

9,278   
6,760   
11,031   
2,401   
1,423   
5,948   

ITEM 7.   Management's Discussion and Analysis of Financial Condition and Results of Operations  

This Annual Report on Form 10-K contains forward-looking statements within the meaning of the federal securities laws. These statements 
are subject  to risks  and uncertainties  that  could cause actual results and  events to differ materially from  those expressed or implied  by  such 
forward-looking statements. For a detailed discussion of these risks and uncertainties, see the “Risk Factors” section in Item 1A of Part I of this 
Form 10-K. We caution the reader not to place undue reliance on these forward-looking statements, which reflect management’s analysis only 
as of the date of this Form 10-K. We undertake no obligation to update forward-looking statements to reflect events or circumstances occurring 
after the date of this Form 10-K.  

The following discussion and analysis should be read in conjunction with our consolidated financial statements and the related notes to 

those statements contained elsewhere in this Annual Report on Form 10-K.  

General Overview  

We  provide  cryogenic  logistics  solutions  to  the  life  sciences  industry  through  a  combination  of  purpose-built  proprietary  packaging, 
information technology and specialized cold chain logistics knowhow. We view our solutions as disruptive to the “older technologies” of dry ice 
and liquid nitrogen, in that our solutions are comprehensive and combine our competencies in configurations that are customized to our client’s 
requirements.  We  provide  comprehensive,  reliable,  economic  alternatives  to  all  existing  logistics  solutions  and  services  utilized  for  frozen 
shipping  in the  life  sciences  industry  (e.g.,  personalized medicine, cell therapies,  stem  cells,  cell  lines,  vaccines, diagnostic  materials,  semen, 
eggs, embryos, cord blood, bio-pharmaceuticals, infectious substances, and other commodities that require continuous exposure to cryogenic or 
frozen temperatures). As part of our services, we provide the ability to monitor, record and archive crucial information for each shipment that 
can be used for scientific and regulatory purposes.  

Our Cryoport Express ® Solutions include a sophisticated cloud-based logistics operating platform, which is branded as the Cryoportal™. 
The Cryoportal™ supports the management of the entire shipment and logistics process through a single interface, including initial order input, 
document preparation, customs clearance, courier management, shipment tracking, issue resolution, and delivery. In addition, it provides unique 
and incisive information dashboards and validation documentation for every shipment. The Cryoportal™ records and retains a fully documented 
“chain-of-custody” and, at the client’s option, “chain-of-condition” for every shipment, helping ensure that quality, safety, efficacy, and stability 
of  shipped  commodities  are  maintained  throughout  the  process.  This  recorded  and  archived  information  allows  our  clients  to  meet  exacting 
requirements necessary for scientific work and for proof of regulatory compliance during the logistics phase.  

33 

   
     
   
   
   
   
   
   
    
  
  
  
  
  
    
    
    
    
  
  
  
  
    
    
    
    
    
    
    
  
  
  
  
    
    
    
    
  
  
  
  
    
    
    
    
    
The  branded  packaging  for  our  Cryoport  Express  ®  Solutions  includes  our  liquid  nitrogen  dry  vapor  shippers,  the  Cryoport  Express  ® 
Shippers.  The  Cryoport  Express  ®  Shippers  are  cost-effective  and  reusable  cryogenic  transport  containers  (our  standard  shipper  is  a  patented 
vacuum  flask)  utilizing  an  innovative  application  of  “dry  vapor”  liquid  nitrogen  (“LN2”)  technology.  Cryoport  Express  ®  Shippers  are 
International Air Transport Association (“IATA”) certified and validated to maintain stable temperatures of minus 150° C and below for a 10-
day dynamic shipment period. The Company currently features three Cryoport Express ® Shippers: the Standard Dry Shipper (holding up to 75 
2.0 ml vials), the High Volume Dry Shipper (holding up to 500 2.0 ml vials) and the recently introduced Cryoport Express ® CXVC1 Shipper 
(holding up to 1,500 2.0 ml vials). In addition, we assist clients with internal secondary packaging as well (e.g., vials, canes, straws, plates, etc.)  

Our most used solution is the “turnkey” solution, which can be accessed directly through our cloud-based Cryoportal™ or by contacting 
Cryoport Client Care for order entry. Once an order is placed and cleared, we ship a fully charged Cryoport Express ® Shipper to the client who 
conveniently  loads  its  frozen  commodity  into  the  inner  chamber  of  the  Cryoport  Express  ®  Shipper  .   The  customer  then  closes  the  shipper 
package and reseals the shipping box displaying the next recipient’s address (“Flap A”) for pre-arranged carrier pick up.  Cryoport arranges for 
the pick-up of the parcel by a shipping service provider, which is designated by the client or chosen by Cryoport, for delivery to the client’s 
intended recipient.  The recipient simply opens the shipper package and removes the frozen commodity that  has been shipped.  The recipient 
then reseals the package, displaying the nearest Cryoport Operations Center address (“Flap B”), making it ready for pre-arranged carrier pick-up. 
The  When  the  Cryoport  Operations  Center  receives  the  Cryoport  Express  ®  Shipper,  it  is  cleaned,  put  through  quality  assurance  testing,  and 
returned to inventory for reuse.  

In late 2012, we shifted our focus to become a comprehensive cryogenic logistics solutions provider. Recognizing that clients in the life 
sciences industry have varying requirements, we unbundled our technologies, establishing customer facing solutions and taking a consultative 
approach to the market. Today, in addition to our standard “Turn-key Solution,” described above, we also provide the following customer facing, 
value-added solutions to address our various clients’ needs:  

• 

• 

• 

• 

• 

• 

“ Customer Staged Solution ,” designed for clients making 50 or more shipments per month. Under this solution, we supply an inventory of 
our Cryoport Express ® Shippers to our customer, in an uncharged state, enabling our customer (after training/certification) to charge them 
with  liquid  nitrogen  and  use  our  Cryoportal™  to  enter  orders  with  shipping  and  delivery  service  providers  for  the  transportation  of  the 
package.  Once  the  order  is  released,  our  customer  services  professionals  monitor  the  shipment  and  the  return  of  the  shipper  to  us  for 
cleaning, quality assurance testing and reuse. 

“ Customer Managed Solution ,” a limited customer implemented solution whereby we supply our Cryoport Express ® Shippers to clients 
in  a  fully  charged  state,  but  leaving  it  to  the  client  to  manage  the  shipping,  including  the  selection  of  the  shipping  and  delivery  service 
provider and the return of the shipper to us. . 

“  powered  by  Cryoport  SM  ,”  available  to  providers  of  shipping  and  delivery  services  who  seek  to  offer  a  “branded”  cryogenic  logistics 
solution as part of their service offerings, with “ powered by Cryoport  SM ” appearing prominently on the offering software interface and 
packaging. This solution can also be private labeled upon meeting certain requirements, such as minimum required shipping volumes. 

“ Integrated Solution, ” which is our outsource solution. It is our most comprehensive solution and involves our management of the entire 
cryogenic  logistics  process  for  our  client,  including  Cryoport  employees  at  the  client’s  site  to  manage  the  client’s  cryogenic  logistics 
function in total. 

“  Regenerative  Medicine  Point-of-Care  Repository  Solution,  ”  designed  for  allogeneic  therapies.  In  this  model  we  supply  our  Cryoport 
Express  ® Shipper to ship and store cryogenically preserved life science products for up to 6 days (or longer periods with supplementary 
shippers) at a point-of-care site, with the Cryoport Express  ® Shipper serving as a temporary freezer/repository enabling the efficient and 
effective  distribution  of  temperature  sensitive  allogeneic  cell-based  therapies  without  the  expense,  inconvenience,  and  potential  costly 
failure  of  an  on-sight,  cryopreservation  device.  Our  customer  service  professionals  monitor  each  shipment  throughout  the  predetermined 
process including the return of the shipper to us. When the Cryoport Operations Center receives the Cryoport Express ® Shipper package it 
is cleaned, put through quality assurance testing, and returned to inventory for reuse. 

“  Personalized  Medicine  and  Cell-based  Immunotherapy  Solution,  ”  designed  for  autologous  therapies.  In  this  model  our  Cryoport 
Express ® Shipper serves as an enabling technology for the safe transportation of manufactured autologous cellular-based immunotherapy 
market by providing a comprehensive logistics solution for the verified chain of custody and condition transport from, (a) the collection of 
the patient’s cells in a hospital setting, to (b) a central processing facility where they are manufactured into a personalized medicine, to (c) 
the safe, cryogenically preserved return of these irreplaceable cells to a point-of-care treatment facility.  If required, the Cryoport Express ® 
Shipper can then serve as a temporary freezer/repository to allow the efficient distribution of this personalized medicine to the patient when 
and  where  the  medical  provider  needs  it  most  without  the  expense,  inconvenience,  and  potential  costly  failure  of  an  on-sight, 
cryopreservation device. Our customer services professionals monitor each shipment throughout the predetermined process, including the 
return of the shipper to us. When the Cryoport Operations Center receives the Cryoport Express ® Shipper package it is cleaned, put through 
quality assurance testing, and returned to inventory for reuse. 

34 

   
   
   
   
   
   
     
   
    
   
  
Strategic Logistics Alliances  

We have sought to establish strategic alliances as a method of marketing our solutions providing minus 150° C shipping conditions to the 
life  sciences  industry.  We  have  focused  our  efforts  on  leading  companies  in  the  logistics  services  industry  as  well  as  participants  in  the  life 
sciences industry. In connection with our alliances with providers of shipping services, we refer to their respective offerings as “ powered by 
Cryoport SM ” to reflect our solutions being integrated into our alliance partner’s services.  

Cryoport  now  serves  and  supports  the  three  largest  integrators  in  the  world,  responsible  for  over 85%  of worldwide  airfreight,  with  its 
advanced cryogenic logistics solutions for life sciences. We operate  with each independently and confidentially in support  of  their  respective 
market  and  sales  strategies.  We  maintain  our  independent  partnerships  with  strict  confidentiality  guidelines  within  the  Company.  These 
agreements represent a significant validation of our solutions and the way we conduct our business.  

FedEx.  In  January  2013,  we  entered  into  a  master  agreement  with  Federal  Express  Corporation  (“FedEx”)  (the  “FedEx  Agreement”) 
renewing these services and providing FedEx with a non-exclusive license and right to use a customized version of our Cryoportal  TM for the 
management of shipments made by FedEx customers. The FedEx Agreement became effective on January 1, 2013 and, unless sooner terminated 
as  provided  in  the  FedEx  Agreement,  expires  on  December  31,  2015.  FedEx  has  the  right  to  terminate  this  agreement  at  any  time  for 
convenience upon 180 days’ notice.  

Under  our  FedEx  Agreement,  we  provide  frozen  shipping  logistics  services  through  the  combination  of  our  purpose-built  proprietary 
technologies  and  turnkey  management  processes.  FedEx  markets  and  sells  Cryoport’s  services  for  frozen  temperature-controlled  cold  chain 
transportation  as  its  FedEx  ®  Deep  Frozen  Shipping  Solution  on  a  non-exclusive  basis  and  at  its  sole  expense.  During  fiscal  year  2013,  the 
Company  worked  closely  with  FedEx  to  further  align  its  sales  efforts  and  accelerate  penetration  within  FedEx’s  life  sciences  customer  base 
through improved processes, sales incentives, joint customer calls and more frequent communication at the sales and executive level. In addition, 
FedEx has developed a FedEx branded version of the Cryoportal TM software platform, which is “ powered by Cryoport SM ” for use by FedEx 
and its customers giving them access to the full capabilities of our cloud-based logistics management software platform.  

DHL. In June 2014, we entered into a master agreement with LifeConEx, a part of DHL Global Forwarding (“DHL”). This relationship 
with DHL is a further implementation of the Company’s expansion of distribution partnerships under the “ powered by Cryoport  SM ” model 
described above, allowing us to expand our sales and marketing reach through our partners and build awareness of the benefits of our validated 
cryogenic  solution  offerings.  DHL  can  now  enhance  and  supplement  its  cold  chain  logistics  offerings  to  its  life  sciences  and  healthcare 
customers with Cryoport’s validated cryogenic solutions. DHL added 15 additional certified Life Sciences stations in the second quarter of 2014 
bringing the Thermonet network to 60 stations in operation. Over the course of rolling out our new relationship, this expanded network will offer 
Cryoport’s cryogenic solutions under the DHL brands as “ powered by Cryoport SM ”. In addition, DHL’s customers will be able to have direct 
access to our cloud-based order entry and tracking portal to order Cryoport Express ® Solutions and receive preferred DHL shipping rates and 
discounts. Our proprietary logistics management operating platform, the Cryoportal TM , is integrated with DHL’s tracking and billing systems to 
provide  DHL  life  sciences  and  healthcare  customers  with  a  seamless  way  of  accessing  critical  information  regarding  shipments  of  biological 
material worldwide.  

UPS. In October 2014, we added United Parcel Services, Inc. (“UPS”) as our third major distributor by entering into an agreement with 
UPS Oasis Supply Corporation, a part of UPS, whereby UPS will offer our validated and comprehensive cryogenic solutions to its life sciences 
and healthcare customers on a global basis. This relationship with UPS is a further implementation of the Company’s expansion of distributors 
under the “ powered by Cryoport SM ” model described above, allowing us to further expand our sales and marketing reach through our partners 
and build awareness of the benefits of our validated cryogenic solution offerings through UPS.  

Over the course of rolling out our new relationship with UPS, UPS customers will have direct access to our cloud-based order entry and 
tracking portal to order Cryoport Express ® Solutions and gain access to UPS’s broad array of domestic and international shipping and logistics 
solutions at competitive prices. Our proprietary logistics management operating platform, the Cryoportal TM , is integrated with UPS’s tracking 
and  billing  systems  to  provide  UPS  life  sciences  and  healthcare  customers  with  a  seamless  way  of  accessing  critical  information  regarding 
shipments of biological material worldwide.  

35 

   
   
   
   
   
   
   
   
   
  
These agreements the three largest integrators in the world represent a significant validation of our solutions and the way we conduct our 

business.  

Life Sciences Agreements  

Zoetis. In December 2012, we  signed an agreement with Pfizer  Inc. relating to  Zoetis Inc. (formerly the animal health  business unit of 
Pfizer  Inc.)  pursuant  to  which  we  were  engaged  to  manage  frozen  shipments  of  a  key  poultry  vaccine.  Under  this  arrangement,  Cryoport 
provides on-site logistics personnel and its logistics management operating platform, the Cryoportal  TM to manage shipments from the Zoetis 
manufacturing  site  in  the  United  States  to  domestic  customers  as  well  as  various  international  distribution  centers.  As  part  of  our  logistics 
management services, Cryoport is constantly analyzing logistics data and processes to further introduce economies and reliability throughout the 
network,  ensuring  products  arrive  at  their  destinations  in  specified  conditions,  on-time  and  with  the  optimum  utilization  of  resources.  The 
Company  manages  Zoetis’  total  fleet  of  dewar  flask  shippers  used  for  this  purpose,  including  liquid  nitrogen  shippers.  In  July  2013  the 
agreement  was  amended  to expand  Cryoport’s scope  to  manage  all logistics  of  Zoetis’ key  frozen poultry  vaccine  to  all  Zoetis’ international 
distribution centers as well as all domestic shipments. In October 2013, the agreement was further amended to further expand Cryoport’s role to 
include the logistics management for a second poultry vaccine.  

Liventa Biosciences. In February 2014, we entered into a services agreement with Liventa Bioscience, Inc. (“Liventa”), a privately-held, 
commercial  stage  biotechnology  company  focused  on cell-based  biologics in  the  orthopedic  industry.  Under  this  agreement,  Liventa  will  use 
Cryoport’s  Regenerative  Medicine  Point-of-Care  Repository  Solution  for  the  logistics  of  its  cell-based  therapies  requiring  cryogenic 
temperatures and also provide Cryoport Express ® Solutions to other biologics suppliers within the orthopedic arena. The agreement combines 
Cryoport’s proprietary, purpose-built cold chain logistics solutions for cell-based and advanced biologic tissue forms with Liventa’s distribution 
capability  to  orthopedic  care  providers.  The  implementation  of  Cryoport’s  Regenerative  Medicine  Point-of-Care  Repository  Solution  will 
eliminate  the  risks  of  degradation  and  also  eliminate  the  need  for  expensive  onsite  cryogenic  freezers  for  storage  of  cell-based  orthopedic 
therapies. This will enable Liventa to confidently serve orthopedic practices, surgical centers, pain clinics, hospitals and, eventually, pharmacies 
and specialty care providers. The agreement has an initial three-year term and may be renewed for consecutive three-year terms, unless earlier 
terminated  by  either  party.  Liventa  also  agreed  to  certain  performance  criteria  and  the  issuance  of  150,000  shares  of  its  common  stock  to 
Cryoport in exchange for an opportunity for the exclusive right to offer, market and promote Cryoport Express  ® Solutions for cellular-based 
therapies requiring cryogenic temperatures for use in the orthopedic arena in the United States.  

In summary, we serve the life sciences industry with cryogenic logistics solutions that are advanced, comprehensive, reliable, validated, 
and efficient. Our clients include those companies and institutions that have logistics requirements for personalized medicine, immunotherapies, 
stem cells, cell lines, tissue, vaccines, in-vitro fertilization, cord blood, and other temperature sensitive commodities of life sciences.  

 Going Concern  

As  reported  in  the  Report  of  Independent  Registered  Public  Accounting  Firm  to  our  March  31,  2015  and  2014  consolidated  financial 
statements,  we  have  incurred  recurring  losses  and  negative  cash  flows  from  operations  since  inception.  These  factors,  among  others,  raise 
substantial doubt about our ability to continue as a going concern.  

We expect to continue to incur substantial additional operating losses from costs related to the commercialization of our Cryoport Express 
® Solutions and do not expect that revenues from operations will be sufficient to satisfy our funding requirements in the near term. We believe 
that our cash resources at March 31, 2015, and funds currently being raised through a Class B convertible preferred stock offering together with 
the revenues generated from our services will be sufficient to sustain our planned operations into the third quarter of fiscal year 2016; however, 
we must obtain additional capital to fund operations thereafter and for the achievement of sustained profitable operations. These factors raise 
substantial doubt about our ability to continue as a going concern. We are currently working on funding alternatives in order to secure sufficient 
operating capital to allow us to continue to operate as a going concern.  

Future  capital  requirements  will  depend  upon  many  factors,  including  the  success  of  our  commercialization  efforts  and  the  level  of 
customer adoption of our Cryoport Express ® Solutions as well as our ability to establish additional collaborative arrangements. We cannot make 
any assurances that the sales ramp will lead to achievement of sustained profitable operations or that any additional financing will be completed 
on a timely basis on acceptable terms or at all. Management’s inability to successfully achieve significant revenue increases or its cost reduction 
strategies or to complete any other financing will adversely impact our ability to continue as a going concern. To address this issue, the Company 
is seeking additional capitalization to properly fund our efforts to become a self-sustaining financially viable entity.  

36 

    
   
   
   
   
   
   
   
   
   
  
While  we  increased  revenue  year-over-year  by  48%  to  $3.9  million  for  the  fiscal  year  ended  March  31,  2015,  our  revenue  is  still 
significantly lower than our operating expenses during the year and we have no assurance of the level of future revenues. We incurred a net loss 
of $7.0 million and used cash of $4.1 million in our operating activities during the year ended March 31, 2015. We had negative working capital 
of $835,000 and had cash and cash equivalents of $1.4 million at March 31, 2015.  

We  are  currently  funding  our  operations  through  a  preferred  stock  offering  (see  Note  11  in  the  accompanying  consolidated  financial 
statements) and plan to raise additional funds through additional debt or equity offerings to cover general working capital needs and sales and 
marketing initiatives to expand our customer base and increase sales. There is no assurance that funds can be secured or if these funds would 
allow  us  to  continue  our  operations  until  more  significant  revenues  can  be  generated  or  more  funding  can  be  secured.  These  matters  raise 
substantial doubt about our ability to continue as a going concern.  

Recent Developments  

The  Board  of  Directors  authorized  the  twelve  to  one  reverse  stock  split  that  became  effective  on  May  19,  2015.  All  prior  periods 
presented in this Report have been adjusted to reflect the twelve to one reverse stock split. Financial information updated by this capital change 
includes  earnings  per  common  share,  dividends  per  common  share,  stock  price  per  common  share,  weighted  average  common  shares, 
outstanding common shares, treasury shares, common stock, additional paid-in capital, and share-based compensation.  

 Liquidity and Capital Resources  

As of March 31, 2015, the Company had cash and cash equivalents of $1.4 million and negative working capital of $835,000. Historically, 

we have financed our operations primarily through sales of our debt and equity securities.  

For the year ended March 31, 2015, we used $4.1 million of cash for operations primarily as a result of the net loss of $7.0 million offset 
by  non-cash  expenses  of  $2.5  million  primarily  comprised  of  amortization  of  debt  discount  and  deferred  financing  costs,  stock-based 
compensation expense, and depreciation and amortization. Also contributing to the cash impact of our net operating loss (excluding non-cash 
items) was an increase in accounts receivable of $76,600 due to increased revenues.  

Net cash used in investing activities of $70,100 during the year ended March 31, 2015 was primarily due to the purchase of the recently 

introduced Cryoport Express ® CXVC1 Shippers (holding up to fifteen hundred 2.0 ml vials).  

Net cash provided by financing activities totaled $5.2 million during the year ended March 31, 2015, and resulted from net proceeds from 
the issuance of convertible preferred stock of $4.6 million, proceeds from the exercise of stock options and warrants of $92,600 and proceeds of 
$915,000 from notes payable, partially offset by the repayment of notes payable of $173,600, convertible debentures of $50,000, offering and 
financing costs of $30,000 and the repayment of related-party notes of $128,000.  

As  discussed  in  Note 2  of  the  accompanying  consolidated  financial  statements,  there  exists  substantial  doubt  regarding  the  Company’s 
ability to continue as a going concern. The Company received gross proceeds of $3.5 million (approximately $2.9 million after offering costs) in 
exchange for the issuance of 291,142 shares of Class A convertible preferred stock and $1.9 million (approximately $1.7 million after offering 
costs) in exchange for the issuance of 161,709 shares of Class B convertible preferred stock during fiscal 2015 which is further described in Note 
11 in the accompanying consolidated financial statements and proceeds of $915,000 from the 7% Bridge Notes (see Note 7). The funds raised 
are  being  used  for  working  capital  purposes  and  to  continue  our  sales  efforts  to  advance  the  Company’s  commercialization  of  the  Cryoport 
Express ® Solutions.  

The  Company’s  management  recognizes  that  the  Company  will  need  to  obtain  additional  capital  to  fund  its  operations  until  sustained 
profitable operations are achieved. Management is currently working on such funding alternatives in order to secure sufficient operating capital 
through  the  end  of  fiscal  year  2016.  Additional  funding  plans  may  include  obtaining  additional  capital  through  equity  and/or  debt  funding 
sources. The Company currently anticipates that it will continue to raise additional capital to fund its short term operating expenses pursuant to 
private placements similar to private placements the Company has conducted in the past. The Company also anticipates seeking to raise up to 
$15 million pursuant to a public offering of its common stock and warrants to provide working capital and to support the Company’s anticipated 
operations and development plans. No assurance can be given that additional capital, if needed, will be available when required or upon terms 
acceptable to the Company.  

In addition, management will continue to review its operations for further cost reductions to extend the time that the Company can operate 
with  its  current  cash  on  hand  and  additional  bridge  financing  and  to  utilize  third  parties  for  services  such  as  its  international  recycling  and 
refurbishment centers to provide for greater flexibility in aligning operational expenses with the changes in sales volumes.   

37 

    
   
   
   
   
   
   
   
    
   
   
   
   
  
Results of Operations  

Results of Operations for Fiscal 2015 Compared to Fiscal 2014  

The following table summarizes certain information derived from our consolidated statements of operations:  

Revenues 
Cost of revenues 

Gross margin 
Selling, general and administrative 
Research and development 
Debt conversion expense 
Interest expense 
Change in fair value of derivative liabilities 
Other expense 
Provision for income taxes 

   Year Ended March 31, 

2015 

2014 

     $ Change       % Change    

($ in 000’s) 

  $ 

3,935     $ 
(2,766 )     

2,660     $ 
(2,223 )     

1,275       
(543 )     

47.9 % 
24.4 % 

1,169       
(6,409 )     
(353 )     
—      
(1,428 )     
—      
(4 )     
(2 )     

437       
(5,106 )     
(409 )     
(13,714 )     
(784 )     
21       
(8 )     
(2 )     

732       
(1,303 )     
56       
13,714       
(644 )     
(21 )     
4       
—      

167.5 % 
25.5 % 
(13.8 )% 
(100 )% 
82.0 % 
(100 )% 
(47.2 )% 
—  

Net loss 

  $ 

(7,027 )   $ 

(19,565 )   $ 

12,538       

(64.1 )% 

Revenues . We generated revenues from customers in all of our target life sciences markets, such as biotech and diagnostic companies, 
pharmaceutical companies, central laboratories, contract research organizations, the reproductive medicine market/in vitro fertilization market, 
and research institutions. Net revenues increased $1.3 million or 47.9% for the year ended March 31, 2015 as compared to the prior year. This 
increase is primarily driven by an overall increase in the number of customers utilizing our services and frequency of shipments compared to the 
prior year, an increase in revenues in the reproductive medicine market and the ramp up and expansion of logistics services provided to Zoetis. 
Revenues in the reproductive medicine market increased by 59% over the prior year to $924,300 for the year ended March 31, 2015, driven by 
continued  success  of  our  telemarketing  activities,  email  and  other  targeted  campaigns  and  in  increased  awareness  of  our  cryogenic  logistics 
solutions in this market. Our revenues from Zoetis were $893,200 for the year ended March 31, 2015, representing a 9% increase over the prior 
year. This is reflective of the expansion of our services, both domestically and globally, provided to Zoetis for a primary poultry vaccine, and the 
addition of logistics management for a second vaccine that was introduced to the market during the fourth calendar quarter of 2013.  

Gross margin and cost of revenues . Gross margins for the year ended March 31, 2015 was 29.7% of revenues, as compared to 16.4% of 
revenues for the prior year. The increase in gross margin is primarily due to the increase in net revenue combined with a reduction in freight as a 
percentage of revenues and a decrease of fixed manufacturing costs. Cost of revenues for the year ended March 31, 2015 was 70.3% of revenues, 
as  compared  to  83.6%  of  revenues  for  the  prior  year.  Our  cost  of  revenues  are  primarily  comprised  of  freight  charges,  payroll  and  related 
expenses  related  to  our  operations  center  in  California,  third-party  charges  for  our  European  and  Asian  operations  centers  in  Holland  and 
Singapore, depreciation expenses of our Cryoport Express® Shippers and supplies and consumables used for our solutions. The increase in cost 
of revenues is primarily due to freight charges from the growth in shipments.  

Selling, general and administrative expenses . Selling, general and administrative expenses increased $1.3 million, or 25.5% for the year 
ended March 31, 2015 as compared to the prior year. This increase is primarily due to salaries and recruiting fees incurred to expand our sales 
force, the engagement of an investor relations firm and related activities, equity based compensation charges, public company related expenses 
including legal, SOX and financial reporting expenses and banking charges as a result of the higher business volume.  

Research  and  development  expenses  . Research and development  expenses  decreased $56,500  or  13.8%  for  the year ended  March  31, 
2015, as compared to the prior year. Our research and development efforts are focused on continually improving the features of the Cryoport 
Express ® Solutions including the Company’s cloud-based logistics management platform, the Cryoportal TM , the Cryoport Express ®  Shippers 
and development of additional accessories to facilitate the efficient shipment of life science commodities using our solution. We use an outside 
software  development  company  and  other  third  parties  to  provide  some  of  these  services.  Research  and  development  expenses  to  date  have 
consisted primarily of costs associated with the continually improving the features of the Cryoport Express ® Solution including the web based 
customer service portal and the Cryoport Express ® Shippers. Further, these efforts are expected to lead to the introduction of shippers of varying 
sizes  based  on  market  requirements,  constructed  of  lower  cost  materials  and  utilizing  high  volume  manufacturing  methods  that  will  make  it 
practical to provide the cryogenic packages offered by the Cryoport Express ® Solution. Other research and development effort has been directed 
toward improvements to the liquid nitrogen retention system to render it more reliable in the general shipping environment and to the design of 
the outer packaging. Alternative phase change materials in place of liquid nitrogen may be used to increase the potential markets these shippers 
can serve such as ambient and 2°- 8°C markets.  

38 

   
   
   
   
   
   
   
   
   
  
  
    
  
    
  
  
  
  
    
  
  
    
  
    
  
  
  
  
      
      
      
    
    
  
    
        
        
        
    
    
    
    
    
    
    
    
    
  
    
        
        
        
    
Debt  conversion  expense.  Debt  conversion  expense  for  the  year  ended  March  31,  2014  of $13.7  million  was  related  to  the  induced 
conversion  of  $4.1  million  of  aggregate  principal  and  accrued  interest  from  the  convertible  bridge  notes into  shares  of  common  stock  and 
warrants. Debt conversion expense represents the fair value of the securities transferred in excess of the fair value of the securities issuable upon 
the original conversion terms of the bridge notes.  The Company calculated the fair value of the common stock issued by using the closing price 
of the stock on the date of issuance.  The fair value of the warrants was calculated using the Black-Scholes option pricing model.  

Interest expense . Interest expense increased $643,600 for the year ended March 31, 2015, as compared to the prior year. Interest expense 
included amortization of the debt discount and deferred financing fees of approximately $1.1 million, of which $826,900 related to the fair value 
of the beneficial conversion feature of the 5% Bridge Notes that was triggered by the convertible preferred stock offering, interest expense on 
our 5% Bridge Notes of approximately $10,600, accrued interest on our related-party notes payable of approximately $33,500, amortization of 
the debt discount on the 7% Bridge Notes of $237,500 and related interest expense of $15,500. Interest expense for the year ended March 31, 
2014 included amortization of the debt discount and deferred financing fees of approximately $678,900, interest expense on our bridge notes of 
approximately $71,600 and accrued interest on our related party notes payable of approximately $36,500.  

Change  in  fair  value  of  derivative  liabilities  .  The  warrants  classified  as  derivative  liabilities  expired  in  April  2014.  The  gain  on  the 
change in fair value of derivative liabilities was $20,800 for the year ended March 31, 2014 as a result of a decrease in the value of our warrant 
derivatives, due primarily to a decrease in our stock price.  

Other  expense,  net  .  The  other  expense,  net  for  the  year  ended  March  31,  2015  is  primarily  due  to  administrative  charges  and  foreign 

exchange losses on accounts receivable and payable invoices.  

Off-Balance Sheet Arrangements  

We do not have any off balance sheet arrangements within the meaning of Item 303(a)(4) of Regulation S-K.  

Contractual Obligations  

The  following  table  summarizes  our  contractual  obligations  as  of  March  31,  2015,  and  the  effects  such  obligations  are  expected  to  have  on 
liquidity and cash flow in future periods ($ in ‘000’s):  

Contractual obligations 
Operating lease obligations (1) 
Notes payable (2) 
Other obligations (3) 
Total 

Total   

Less than  
1 Year   

     1-3 Years   

     4-5 Years   

After  
5 Years   

  $ 

  $ 

38     $ 
757       
1,263       
2,058     $ 

27     $ 
757       
1,237       
2,021     $ 

11     $ 
—      
26       
37     $ 

—    $ 
—      
—      
—    $ 

—  
—  
—  
—  

(1)  The  operating  lease  obligations  are  primarily  related  to  the  facility  lease  for  our  principal  executive  office  in  Lake  Forest,  California, 
which expires June 30, 2015. In May 2015, we amended the lease to convert to a month-to-month basis, commencing July 1, 2015. The 
base rent will be $9,500 and either party will have the right to cancel this month-to-month agreement by giving the other party a minimum 
of a 90-day prior written notice. We also lease certain office equipment. 

(2)  Notes payable represent secured convertible promissory notes and accrued interest at 7% per annum which were issued in December 2014 
through February 2015 to certain accredited investors pursuant to the terms of subscription agreements and letters of investment intent. All 
principal and accrued interest is due July 1, 2015. All unpaid principal and interest was paid in April 2015. 

(3)  Other  long-term  obligations  represent  outstanding  unsecured  indebtedness  and  accrued  interest  owed  to  five  related  parties  which  bear 

interest at the rate of 6% per annum. The unpaid principal and accrued interest is due at maturity on various dates through May 1, 2016. 

39 

    
   
   
   
     
   
   
   
   
   
   
  
  
  
    
    
  
    
        
        
        
        
    
    
    
Impact of Inflation  

From time to time, Cryoport experiences price increases from third party manufacturers and these increases cannot always be passed on to 
Cryoport’s customers. While these price increases have not had a material impact on Cryoport’s historical operations or profitability in the past, 
they could affect revenues in the future.  

Critical Accounting Policies and Estimates  

Our discussion and analysis  of  our consolidated financial  condition  and  results of operations  are based  upon our  consolidated  financial 
statements, which  have been prepared  in  conformity with  accounting  principles generally  accepted in  the  U.S., or  GAAP. The preparation of 
these  consolidated  financial  statements  requires  us  to  make  estimates  and  assumptions  that  affect  the  reported  amounts  of  assets,  liabilities, 
revenues  and  expenses,  and  related  disclosure  of  contingent  assets  and  liabilities  reported  in  our  consolidated  financial  statements.  The 
estimation process requires assumptions to be made about future events and conditions, and is consequently inherently subjective and uncertain. 
Actual results could differ materially from our estimates.  

The  SEC  defines  critical  accounting  policies  as  those  that  are,  in  management’s  view,  most  important  to  the  portrayal  of  our  financial 
condition and results of operations and most demanding of our judgment. We consider the following policies to be critical to an understanding of 
our consolidated financial statements and the uncertainties associated with the complex judgments made by us that could impact our results of 
operations, financial position and cash flows. See Note 2: “ Summary of Significant Accounting Policies ” of our accompanying consolidated 
financial statements for a description of our critical accounting policies and estimates.  

New Accounting Pronouncements  

See  Note 2:  “  Recent  Accounting  Pronouncements  ”  of  our  accompanying  consolidated  financial  statements  for  a  description  of  recent 
accounting pronouncements that may have a significant impact on our financial reporting and our expectations of their impact on our results of 
operations and financial condition.  

Item 7A.       Quantitative and Qualitative Disclosures About Market Risk  

Changes in United States interest rates would affect the interest earned on our cash and cash equivalents.  

Based on our overall cash and cash equivalents interest rate exposure at March 31, 2015, a near-term change in interest rates, based on 

historical movements, would not have a material adverse effect on our financial position or results of operations.  

We have operated primarily in the United States. Accordingly, we have not had any significant exposure to foreign currency rate 

fluctuations.  

Item 8.   Financial Statements and Supplementary Data  

Our annual consolidated financial statements are included in Item 15 of this report.  

Item 9.  Changes in and Disagreements with Accountants on Accounting and Financial Disclosure  

None.  

Item 9A.   Controls and Procedures  

(a) Evaluation of Disclosure Controls and Procedures  

The term “disclosure controls and procedures” (defined in Rule 13a-15(e) under the Securities and Exchange Act of 1934 (the “Exchange 
Act”)  refers  to  the  controls  and  other  procedures  of  a  company  that  are  designed  to  ensure  that  information  required  to  be  disclosed  by  a 
company in the reports that it files under the Exchange Act is recorded, processed, summarized and reported within the required time periods. 
Under the supervision and with the participation of our management, including our Chief Executive Officer and Chief Financial Officer, we have 
conducted an evaluation of the effectiveness of the design and operation of our disclosure controls and procedures, as of March 31, 2015. Based 
on this evaluation, our Chief Executive Officer and Chief Financial Officer concluded that our disclosure controls and procedures were effective 
as of March 31, 2015 to ensure the timely disclosure of required information in our Securities and Exchange Commission filings.  

Because of inherent limitations, internal control over financial reporting may not prevent or detect misstatements. In addition, the design of 
any system of control is based upon certain assumptions about the likelihood of future events, and there can be no assurance that any design will 
succeed in achieving its stated goals under all future events, no matter how remote. Accordingly, even effective internal control over financial 
reporting can only provide reasonable assurance of achieving their control objectives.  

40 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
(b) Management’s Report on Internal Control Over Financial Reporting .  

Management’s Report on Internal Control Over Financial Reporting which appears on the following page is incorporated herein by this 

reference.  

(c) Changes in internal control over financial reporting  

During  the  quarter  ended  March  31,  2015,  there  were  no  changes  in  our  internal  control  over  financial  reporting  that  have  materially 

affected, or are reasonably likely to materially affect, our internal control over financial reporting.  

Item 9B.   Other Information  

Based  on  the  recommendation  of  the  Compensation  Committee  and  approval  by  the  Board,  Mr.  Jerrell  W.  Shelton,  the  company’s 
President and Chief Executive Officer, was awarded an option to purchase 387,500 shares of the Company’s common stock at an exercise price 
equal to the closing price of the Company’s common stock on the date of the grant, or $4.80 per share, on December 18, 2014, of which 262,500 
shares  were  not  granted  pursuant  to  any  of  the  Company’s  equity  incentive  plans.  The  option  vests  in  monthly  over  four  years  and  expires 
December 17, 2024. The foregoing description is qualified in its entirety by reference to the option agreement, which is attached as Exhibit 10.42 
to this Annual Report on Form 10-K and is incorporated by reference herein.  

41 

   
   
     
   
   
   
   
  
CRYOPORT, INC.  
MANAGEMENT’S REPORT ON  
INTERNAL CONTROL OVER FINANCIAL REPORTING  

The management of the Company is responsible for establishing and maintaining effective internal control over financial reporting and for 
the  assessment  of  the  effectiveness  of  internal  control  over  financial  reporting.  The  Company’s  internal  control  over  financial  reporting  is  a 
process designed, as defined in Rule 13a-15(f) under the Securities and Exchange Act of 1934, to provide reasonable assurance regarding the 
reliability  of  financial reporting  and  the  preparation  of  consolidated  financial  statements  for  external purposes  in  accordance  with  accounting 
principles generally accepted in the United States of America.  

The Company’s internal control over financial reporting is supported by written policies and procedures that:  

• 

• 

• 

pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the 
Company’s assets; 

provide reasonable assurance that transactions are recorded as necessary to permit preparation of consolidated financial statements in 
accordance with accounting principles generally accepted in the United States of America, and that receipts and expenditures of the 
Company are being made only in accordance with authorizations of the Company’s management and directors; and 

provide  reasonable  assurance  regarding  prevention  or  timely  detection  of  unauthorized  acquisition,  use  or  disposition  of  the 
Company’s assets that could have a material effect on the consolidated financial statements. 

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Projections of any 
evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that 
the degree of compliance with the policies or procedures may deteriorate.  

In  connection  with  the  preparation  of  the  Company’s  annual  consolidated  financial  statements,  management  of  the  Company  has 
undertaken an assessment of the effectiveness of the Company’s internal control over financial reporting based on criteria established in Internal 
Control  —  Integrated  Framework  (1992)  issued  by  the  Committee  of  Sponsoring  Organizations  of  the  Treadway  Commission  (“the  COSO 
Framework”). Management’s  assessment included  an evaluation  of the  design  of the  Company’s internal control  over financial reporting and 
testing of the operational effectiveness of the Company’s internal control over financial reporting.  

Based  on  this  assessment,  management  has  concluded  that  the  Company’s  internal  control  over  financial  reporting  was  effective  as  of 

March 31, 2015.  

By: 

By: 

/s/ JERRELL W. SHELTON 
Jerrell W. Shelton, 
Chief Executive Officer and Director 

/s/ ROBERT STEFANOVICH 
Robert Stefanovich, 
Chief Financial Officer 

May 19, 2015  

42 

   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
Item 10.   Directors, Executive Officers and Corporate Governance  

PART III  

The  information  required  under  this  item  is  incorporated  by  reference  from  our  definitive  proxy  statement  related  to  our  2015  Annual 

Meeting of Stockholders, or the Proxy Statement, to be filed pursuant to Regulation 14A, on or before July 31, 2015.  

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION  

None.  

Item 11.   Executive Compensation  

Executive Officers of the Company  

The Company’s current executive officers are as follows:  

Jerrell W. Shelton, age 69, became President and Chief Executive Officer of the Company on November 5, 2012. He served on the Board 
of  Directors  and  standing  committees  of  Solera  Holdings,  Inc.  from  April  2007  through  November  2011.  From  June  2004  to  May  2006, 
Mr. Shelton was the Chairman and CEO of Wellness, Inc., a provider of advanced, integrated hospital and clinical environments. Prior to that, he 
served as CEO of IBM’s WebFountain. From October 1998 to October 1999, Mr. Shelton was Chairman, President and CEO of NDC Holdings 
II, Inc. Between October 1996 and July 1998, he was President and CEO of Continental Graphics Holdings, Inc. and from October 1991 to July 
1996, Mr. Shelton served as President and CEO of Thomson Business Information Group. Mr. Shelton has a B.S. in Business Administration 
from the University of Tennessee and an M.B.A. from Harvard University. Mr. Shelton currently serves on the Advisory Board of Directors and 
the Nominating and Stewardship committee of the Smithsonian Institution Libraries.  

Robert  S.  Stefanovich,  age  50,  became  Chief  Financial  Officer,  Treasurer  and  Corporate  Secretary  for  the  Company  on  June 27,  2011 
following  the  Company’s  filing  of  its  Form 10–K  for  the  fiscal  year  ended  March 31,  2011.  From  June  15,  2012  to  November  4,  2012,  Mr. 
Stefanovich served as the Principal Executive Officer of the Company. From November 2007 through March 2011, Mr. Stefanovich served as 
Chief  Financial  Officer  of  Novalar  Pharmaceuticals,  Inc.,  a  venture-backed  specialty  pharmaceutical  company.  Prior  to  that,  he  held  several 
senior  positions,  including  interim  Chief  Financial  Officer  of  Xcorporeal,  Inc.,  a  publicly  traded  medical  device  company,  Executive  Vice 
President  and  Chief  Financial  Officer  of  Artemis  International  Solutions  Corporation,  a  publicly  traded  software  company,  Chief  Financial 
Officer  and  Secretary  of  Aethlon  Medical  Inc.,  a  publicly  traded  medical  device  company  and  Vice  President  of  Administration  at  SAIC,  a 
Fortune 500 company. Mr. Stefanovich also served as a member of the Software Advisory Group and an Audit Manager with Price Waterhouse 
LLP’s (now PricewaterhouseCoopers) hi-tech practice in San Jose, CA and Frankfurt, Germany. He currently also serves as a board member of 
Project InVision International, a provider of business performance improvement solutions. He received his Masters of Business Administration 
and Engineering from University of Darmstadt, Germany.  

The following table contains information with respect to the compensation for the fiscal years ended March 31, 2015 and 2014 of our chief 
executive  officer,  chief  financial  officer  and  former  chief  executive  officer.  We  refer  to  the  executive  officers  identified  in  this  table  as  our 
“Named Executive Officers.”  

SUMMARY COMPENSATION TABLE  

Name and Principal Position 
Jerrell W. Shelton 

President and Chief Executive Officer     

Robert S. Stefanovich 

Chief Financial Officer 

Fiscal  
Year 

2015       
2014       
2015       
2014       

Salary (1)  
($) 
300,000 (3)     
300,000 (3)     
225,000 (3)     
225,000 (3)     

Bonus  
($) 

—      
—      
—      
—      

Option  
Awards (4)  
($) 
1,625,913 (2)     
930,358 (2)     
307,695 (5)     
201,028 (5)     

All Other  
Compensation 
($) 

Total  
Compensation 
($) 

—      
—      
—      
—      

1, 925,913   
1,230,358   
532,695   
426,028   

(1)  This column represents salary as of the last payroll period prior to or immediately after March 31 of each fiscal year. 
(2)  This amount represents the fair value of all options granted to Mr. Shelton as compensation for services as a director and officer of the 
Company during fiscal year 2015 and 2014. Based on the recommendation of the Compensation Committee and approval by the Board, 
on December 18, 2014 and June 28, 2013, Mr. Shelton was granted an option to purchase 387,500 and 325,209 shares, respectively, of 
common stock in connection with his engagement as Chief Executive Officer of the Company. 

(3)  This amount represents the annual base salary paid. 

43 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
    
  
  
    
  
  
    
  
    
    
    
  
  
  
(4)  This column represents the total grant date fair value of all stock options granted in fiscal 2015 and the Company’s fiscal year ended 
March 31, 2014. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeitures related to service-based vesting 
conditions. For  information on the valuation assumptions with respect to the  grants  made in  fiscal 2015  and 2014, refer  to Note 2 “
Summary of Significant Accounting Policies ” in the accompanying consolidated financial statements. 

(5)  This  amount  represents  the  fair  value  of  all  options  granted  to  Mr.  Stefanovich  as  compensation  for  services  during  fiscal 2015  and 
2015. Based on the recommendation of the Compensation Committee and approval by the Board, on December 18, 2014 and June 28, 
2013, 2012 Mr. Stefanovich was granted an option to purchase 73,334 and 69,918 shares of common stock, respectively. The exercise 
price of the options are equal to the fair value of the Company’s stock as of the grant date. 

Narrative Disclosure to Summary Compensation Table  

Employment Contracts  

Jerrell W. Shelton  

On November 5, 2012, the Company entered into an employment agreement (the “Initial Agreement”) with Mr. Shelton with respect to his 
employment as President and Chief Executive Officer. The Initial Agreement provided a term of six months. The Initial Agreement provided an 
initial annual base salary of $300,000 during the Term.  

In addition, on the date of the Initial Agreement, Mr. Shelton was awarded two options giving him the right to acquire an aggregate of 
137,500 shares of the Company’s common stock at an exercise price equal to the closing price of the Company’s common stock on the date of 
the Agreement, or $2.40 per share. The aggregate number of shares was determined by dividing $350,000 by the closing price of the Company’s 
common stock on the date of the Agreement, or $2.40 per share, and subtracting 8,334 shares, which is the number of shares of common stock 
that Mr. Shelton was given the right to purchase pursuant to the option that was issued to him in connection with his appointment to the Board of 
Directors on October 22, 2012. The first option issued in connection with the Agreement was issued under the Company’s 2011 Stock Incentive 
Plan and provides Mr. Shelton the right to purchase 54,167 shares of the common stock of the Company, which is the maximum that may be 
awarded to Mr. Shelton in this fiscal year under such plan. Mr. Shelton subsequently exercised 54,167 of these shares in May and November 
2013. The second option provided Mr. Shelton the right to purchase 83,334 shares of common stock of the Company and was granted outside of 
the Company’s incentive plans. The options vest in six equal monthly installments during the Term and expire at the earlier of (a) ten years from 
the date of the Agreement, and (b) five (5) years from the date of the resignation and/or removal of the Mr. Shelton as a member of the Board of 
Directors of the Company.  

On  June  28,  2013,  after  the  expiration  of  the  Initial  Agreement,  the  Company  entered  into  a  new  employment  agreement  (the 
“Agreement”) with Mr. Shelton with respect to his employment as President and Chief Executive Officer. The Agreement is effective through 
May 14, 2017 (the “Term”).  

The  Agreement  provides  an  initial  annual  base  salary  of  $300,000  during  the  Term.  In  addition,  on  the  date  of  the  Agreement,  Mr. 
Shelton was awarded options giving him the right to acquire an aggregate of 325,209 shares of the Company’s common stock at an exercise 
price equal to the closing price of the Company’s common stock on the date of the Agreement, or $3.24 per share, and such options were granted 
outside of the Company’s incentive plans. The option vests immediately with respect to 13,551 shares and the remaining right to purchase the 
remaining shares vests in equal monthly installments on the fifth day of each month for forty six months beginning on July 5, 2013 and ending 
on May 5, 2017. Provided that such vesting will be accelerated on the date that the Company files a Form 10-Q or Form 10-K indicating an 
income from operations for the Company in two consecutive fiscal quarters and immediately in the event of a change of control of the Company. 

The options expire at the earlier of (a) ten years from the date of the Agreement, and (b) twenty four (24) months from the date of the 

resignation and/or removal of the Mr. Shelton as Chief Executive Officer of the Company.  

Mr. Shelton has agreed during the Term and for a period of one year following the termination of the Agreement, not to solicit, induce, 
entice  or  attempt  to  solicit,  induce,  or  entice  any  employee  of  the  Company  to  leave  employment  with  the  Company.  Payments  due  to 
Mr. Shelton upon a termination of his employment agreement are described below.  

44 

   
   
   
   
   
   
   
   
   
    
   
  
  
  
Robert S. Stefanovich  

Although the Company does not have a written employment agreement with Mr. Stefanovich, pursuant to the terms of his offer letter, the 
Company  has  agreed  to  pay  Mr. Stefanovich  an  annual  base  salary  of  $225,000  per  year.  In  addition,  he  is  eligible  for  an  incentive  bonus 
targeted at 25% of his annual base salary. Mr. Stefanovich is eligible to participate in all employee benefits plans or arrangements which may be 
offered by the Company during the term of his agreement. The Company shall pay the cost of Mr. Stefanovich’s health insurance coverage in 
accordance with the Company’s plans and policies while he is an employee of the Company. Mr. Stefanovich is also eligible for fifteen (15) paid 
time  off  days  a  year,  and  is  entitled  to  receive  fringe  benefits  ordinarily  and  customarily  provided  by  the  Company  to  its  senior  officers. 
Payments due to Mr. Stefanovich upon a termination of his employment agreement with the Company are described below.  

The Company has no other employment agreements with executive officers of the Company as of March 31, 2015.  

OUTSTANDING EQUITY AWARDS AT FISCAL YEAR END 2015  

The following table shows information regarding unexercised stock options held by our Named Executive Officers as of fiscal year ended 

March 31, 2015:  

Name 
Jerrell W. Shelton 

Robert Stefanovich 

Equity  
 Incentive  
 Plan Awards  
 Number of  
 Securities  
 Underlying  
 Unexercised  
 Unearned  
 Options (#) 

Option  
 Exercise  
 Price ($) 

Option  
 Expiration  
 Date 

  $ 
—  
—  
  $ 
169,380 (3)   $ 
363,280 (4)   $ 
1,302 (5)   $ 
3,334 (6)   $ 
1,875 (7)   $ 
39,328 (8)   $ 
68,750 (9)   $ 

2.28     
2.40     
3.24     
4.80     
10.32     
5.16     
5.16     
3.24     
4.80     

10/22/22 
11/5/22 
6/28/23 
12/18/24 
6/20/21 
8/3/22 
8/3/22 
6/28/23 
12/18/24 

Number of  
 Securities  
 Underlying  
 Unexercised  
 Options (#)  
 Unexercisable      
—      
—      
—      
—      
—      
—      
—      
—      
—      

Number of  
 Securities  
 Underlying  
Unexercised  
 Options (#)  
 Exercisable 

8,334 (1)     
83,334 (2)     
155,829 (3)     
24,220 (4)     
9,115 (5)     
—(6)     
3,125 (7)     
30,590 (8)     
4,584 (9)     

(1)  Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Shelton was granted an option to purchase 
8,334  shares  of  common  stock  exercisable  at  $2.28  per  share  on  October  22,  2012  upon  joining  the  board  of  directors.  Options  vests  in 
twelve equal monthly installments. The exercise price for shares of common stock pursuant to the options is equal to the fair value of the 
Company’s stock as of the grant date. 

(2)  Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Shelton was granted an option to purchase 
137,500 shares of common stock exercisable at $2.40 per share on November 5, 2012, which vests in six equal monthly installments. 54,166 
of these options were issued under the 2011 stock option plan and exercised in May and November 2013 and 83,884 were issued outside of 
a plan. The exercise price for shares of common stock pursuant to the option is equal to the fair value of the Company’s stock as of the grant 
date. 

(3)  Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Shelton was granted an option to purchase 
325,209 shares of common stock exercisable at $3.24 per share on June 28, 2013. The option vests 2/48 th immediately with the remainder 
vesting 1/48 th per month for 46 months. The exercise price for the shares of common stock pursuant to the option is equal to the fair value 
of the Company’s stock on the date of grant. 

(4)  Based on the recommendation of the Compensation Committee and approval by the Board, Mr. Shelton was granted an option to purchase 
387,500 shares of common stock exercisable at $4.80 per share on December 18, 2014. The option vests in monthly installments over a four 
year period, 262,500 shares were issued outside of a plan. The exercise price for the shares of common stock pursuant to the option is equal 
to the fair value of the Company’s stock on the date of grant. 

(5)  Based  on  the  recommendation  of  the  Compensation  Committee  and  approval  by  the  Board,  Mr.  Stefanovich  was  granted  an  option  to 
purchase 10,417 shares of common stock exercisable at $10.32 per share on June 20, 2011. The option vests in six month installments over a 
four year period. The exercise price for the shares of common stock pursuant to the option is equal to the fair value of the Company’s stock 
on the date of grant. 

45 

   
   
     
   
   
   
   
   
  
  
  
  
  
  
    
    
  
    
  
    
  
    
    
  
    
  
    
  
    
  
    
(6)  Based  on  the  recommendation  of  the  Compensation  Committee  and  approval  by  the  Board,  Mr.  Stefanovich  was  granted  an  option  to 
purchase 3,334 shares of common stock exercisable at $5.16 per share on August 3, 2012. The option vests based on certain performance 
criteria. The exercise price for the shares of common stock pursuant to the option is equal to the fair value of the Company’s stock on the 
date of grant 

(7)  Based  on  the  recommendation  of  the  Compensation  Committee  and  approval  by  the  Board,  Mr.  Stefanovich  was  granted  an  option  to 
purchase 5,000 shares of common stock exercisable at $5.16 per share on August 3, 2012. The option vests in six month installments over a 
four year period. The exercise price for the shares of common stock pursuant to the option is equal to the fair value of the Company’s stock 
on the date of grant 

(8)  Based  on  the  recommendation  of  the  Compensation  Committee  and  approval  by  the  Board,  Mr.  Stefanovich  was  granted  an  option  to 
purchase 69,918 shares of common stock exercisable at $3.24 per share on June 28, 2013. The options vest in equal monthly installments 
over four years.  The exercise price for the shares of common stock pursuant to the option is equal to the fair value of the Company’s stock 
on the date of grant. 

(9)  Based  on  the  recommendation  of  the  Compensation  Committee  and  approval  by  the  Board,  Mr.  Stefanovich  was  granted  an  option  to 
purchase  73,334  shares  of  common  stock  exercisable  at  $4.80  per  share  on  December  18,  2014.  The  options  vest  in  equal  monthly 
installments  over  four  years.  The  exercise  price  for  the  shares  of  common  stock  pursuant  to  the  option  is  equal  to  the  fair  value  of  the 
Company’s stock on the date of grant. 

Potential Payments On Termination Or Change In Control  

Pursuant to Mr. Shelton’s employment agreement, if Mr. Shelton terminates the Agreement, dies, or is terminated for “Cause” (as defined 
in the  agreement),  he will  be  entitled to  all  compensation and benefits  that he  earned through  the  date  of  termination.  If  he  is terminated for 
Cause, the Company may, to the extent allowed by law, set off losses, fines or damages that he has caused as a result of his misconduct. If he is 
terminated  “without  cause”  (as  defined  in  the  agreement),  he  will  be  entitled  to  a  continuation  of  his  base  salary  for  three  months  following 
termination  and  one  half  of  unvested  options  as  of  date  of  termination  shall  become  fully  vested.  In  the  event  the  Company  terminates  his 
employment,  except  if  for  “Cause”  (as  defined  in  the  agreement),  within  twelve  (12)  months  after  a  Change  in  Control  (as  defined  in  the 
Cryoport, Inc. 2011 Stock Incentive Plan), then, Mr. Shelton will be entitled to: (i) the continuation of his base salary for twelve (12) months 
following the date of termination, which shall be paid in accordance with the Company’s ordinary payroll practices in effect from time to time, 
and which shall begin on the first payroll period immediately following the date on which the general release and waiver becomes irrevocable; 
and (ii) all options previously granted to Mr. Shelton will become fully vested and exercisable as of the date of termination.  

Pursuant  to  Mr. Stefanovich’s  employment  offer,  in  the  event  that  Mr. Stefanovich’s  employment  with  the  Company  is  terminated  as  a 
result of a “change of control,” as is defined in the Company’s 2009 Stock Incentive Plan, he will be entitled to receive a severance payment 
equal to twelve months of his base salary, continuation of health benefits for a period of twelve months, and the unvested portion of his stock 
option grants immediately shall vest in full. Separately, in the event his employment is terminated by the Company for reasons other than cause, 
Mr. Stefanovich will be entitled to receive a severance payment equal to six months of his base salary plus continuation of health benefits for a 
period of six months.   

The 2002 Plan, 2009 Plan and 2011 Plan each provide that in the event  of a “change of control,” the applicable  option  agreement may 
provide  that  such  options  or  shares  will  become  fully  vested  and  may  be  immediately  exercised  by  the  person  who  holds  the  option,  at  the 
discretion of the board.  

The  Company  does  not  provide  any  additional  payments to  named  executive  officers  upon  their  resignation,  termination,  retirement,  or 

upon a change of control.  

Change in Control Agreements    

There are no understandings, arrangements or agreements known by management at this time which would result in a change in control of 

the Company or any subsidiary.  

Compensation for the Board is governed by the Company’s Compensation Committee.  

DIRECTOR COMPENSATION  

46 

   
   
   
   
   
   
   
   
   
   
   
  
Director Fees  

Effective May 3, 2012 through December 31, 2014, the cash compensation that each non-employee director was paid $40,000 annually, 
except for the non-employee Chairman of the Board who was paid $56,000 annually. In addition, each non-employee director who served as 
Chairman of one or more Board Committees was paid additional cash compensation of $8,000 annually for all Committee Chairmanships.  

Effective January 1, 2015, the compensation plan for non-employee directors was changed as follows:  

Director fees will be paid in cash, restricted shares of the Company’s common stock or a combination thereof, at the option of the director. 

Option 1: Cash compensation of $40,000, paid quarterly;  

Option 2: Cash compensation of $13,000, paid quarterly and $27,000 converted into common stock using the volume weighted average 
price (VWAP) of the stock for the last five days of the trading month ending each quarter, plus an annual grant of options, on the date of the 
Company’s annual meeting, to purchase 16,667 shares of the Company’s common stock; or  

Option 3: No cash compensation but $40,000 converted into common stock using the volume weighted average price (VWAP) of the stock 
for the last five days of the trading month ending each quarter and paid quarterly. This option carries a 15% premium, as there is no cash outlay 
to the Company. The calculation would be $40,000 X 1.15 = $46,000 / VWAP.  

In addition to the compensation options above the following compensation applies to non-employee directors chairing a Board committee. 

This compensation will be paid on the same basis as the Director chose from the options described above:  

Chairman/Lead Director 
Audit Committee 
Compensation Committee 
Nominating and Corporate Governance Committee 

Director Stock Option Grants  

  $ 
  $ 
  $ 
  $ 

25,000   
20,000   
10,000   
10,000   

Annual awards were granted at the shareholders meeting on September 6, 2013. Mr. Rathmann and Mr. Wasserman were each granted an 

option to purchase 6,667 and 4,167 shares, respectively, of the Company’s common stock with an exercise price of $4.56 per share.  

On September 13, 2013, Mr. Zecchini was granted an option to purchase 8,334 shares of the Company’s common stock with an exercise 

price of $4.80 per share when he joined the board.  

On June 16, 2014, Dr. Mandalam was granted an option to purchase 8,334 shares of the Company’s common stock, with an exercise price 

of $5.40 per share when he joined the board.  

Annual awards were granted at the shareholders meeting on August 29, 2014. Mr. Rathmann, Mr. Zecchini and Mr. Mandalam were each 
granted an option to purchase 6,667, 4,167 and 4,167 shares, respectively, of the Company’s common stock with an exercise price of $5.04 per 
share.  

On  December 18, 2014,  Mr. Rathmann,  Mr.  Zecchini  and Mr.  Mandalam were  each  granted  an option to purchase 17,500, 10,834 and 

10,834 shares, respectively, of the Company’s common stock with an exercise price of $4.80 per share.  

On January 12, 2015, Mr. Berman was granted an option to purchase 16,667 shares of the Company’s common stock, with an exercise 

price of $4.56 per share when he joined the board.   

The following table sets forth the director compensation of the non-employee directors of the Company during fiscal 2015.  

Name 
Richard Rathmann 
Stephen Wasserman (3) 
Ramkumar Mandalam(4) 
Edward Zecchini 
Richard Berman (5) 

Fees Earned  
 Or Paid in  
 Cash  
 ($)(1) 

66,688       
20,000       
31,667       
48,500       
20,125       

Stock  
 Awards  
 ($) 

Option  
 Awards  
 ($)(2) 

All Other  
 Compensation  
 ($) 

Total  
 ($) 

—      
—      
—      
—      
—      

101,921       
—      
101,708       
63,264       
64,287       

—      
—      
—      
—      
—      

168,609   
20,000   
133,375   
111,764   
84,412   

47 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
    
    
    
    
  
    
    
    
    
    
(1)  Fees earned or paid in cash as shown in this schedule represent payments and accruals for directors’ services earned during fiscal 2015. 

(2)  This column represents the total grant date fair value of all stock options granted in fiscal 2015. Pursuant to SEC rules, the amounts shown 
exclude the impact of estimated forfeitures related to service-based vesting conditions. For information on the valuation assumptions with 
respect to the grants made in fiscal 2015, refer to Note 2 “ Summary of Significant Accounting Policies” in the accompanying consolidated 
financial statements. 

(3)  Mr. Stephen Wasserman served as director of the Company through the Company’s annual meeting of stockholders on August 29, 2014. 

(4)  Dr. Ramkumar Mandalam became a member of the Board in June 2014. 

(5)  Mr. Richard Berman became a member of the Board in January 2015. 

AUDIT COMMITTEE REPORT  

The  Audit  Committee  of  the  Board  has  furnished  the  following  report  on  the  Company’s  audit  procedures  and  its  relationship  with  its 

independent registered public accounting firm for fiscal 2015.  

The Audit Committee has reviewed and discussed with the Company’s management the audited consolidated financial statements. The Audit 
Committee  has  also  discussed  with  KMJ  Corbin  &  Company  LLP  the  matters  required  to  be  discussed  by  Auditing  Standards  No.  61,  as 
amended (AICPA Professional  Standards, Vol.  1, AU Section 380), as adopted by the Public Company  Accounting Oversight Board  in Rule 
3200T which includes, among other items, matters related to the conduct of the audit of the Company’s consolidated financial statements.  

The Company’s independent registered public accounting firm, KMJ Corbin & Company LLP, also  provided to the Audit Committee the 
written disclosures and the letter required by the Public Company Accounting Oversight Board (PCAOB) Ethics and Independence Rules and 
Standards  as  adopted  by  the  PCAOB,  and  the  Audit  Committee  discussed  with  the  independent  registered  public  accounting  firm  that  firm’s 
independence.  

Based  on  the  review  and  discussions  referred  to  above,  the  Audit  Committee  recommended  to  the  Board  that  the  audited  consolidated 

financial statements be included in the Company’s Annual Report Form 10-K for fiscal 2015 filed with the SEC.  

Audit Committee 
Richard Berman (Chairman) 
Richard Rathmann  
Edward Zecchini  

 Pursuant to Instruction 1 to Item 407(d) of Regulation S-K, the information set forth under “Audit Committee Report” shall not be deemed 
to be “soliciting material” or to be “filed” with the SEC or subject to Regulation 14A or 14C, other than as provided in Item 407 of Regulation S-
K,  or  to  the  liabilities  of  Section  18  of  the  Exchange  Act,  except  to  the  extent  that  we  specifically  request  that  the  information  be  treated  as 
soliciting  material  or  specifically  incorporate  it  by  reference  into  a  document  filed  under  the  Securities  Act  or  the  Exchange  Act.  Such 
information will not be deemed incorporated by reference into any filing under the Securities Act or the Exchange Act, except to the extent we 
specifically incorporate it by reference.  

Item 12.   Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters.  

The following table sets forth information with respect to the beneficial ownership of the Company’s common stock as of May 8, 2015, by 
each  person  or  group  of  affiliated  persons  known  to  the  Company  to  beneficially  own  5%  or  more  of  its  common  stock,  each  director,  each 
named executive officer, and all of its directors and named executive officers as a group. As of May 8, 2015, there were 5,025,577 shares of 
common stock outstanding. Unless otherwise indicated, the address of each beneficial owner listed below is c/o Cryoport, Inc., 20382 Barents 
Sea Circle, Lake Forest, CA 92630.  

48 

   
   
   
   
   
    
   
   
   
   
   
   
   
   
   
  
  
  
  
The following table gives effect to the shares of common stock issuable within 60 days of May 8, 2015, upon the exercise of all options and 
other rights beneficially owned by the indicated stockholders on that date. Unless otherwise indicated, the persons named in the table have sole 
voting and sole investment control with respect to all shares beneficially owned.  

Beneficial Owner 
Executive Officers and Directors: 
Jerrell W. Shelton 
Robert S. Stefanovich 
Richard Rathmann 
Edward Zecchini 
Ramkumar Mandalam Ph.D. 
Richard Berman 

All directors and named executive officers as a group (6 persons)      

Other Stockholders: 
Cranshire Capital Master Fund(3) 

Total for all Directors, Executive Officers and Other Stockholders     

*  Represents less than 1% 

Number of Shares  
of Preferred Stock 
Beneficially Owned   

Number of Shares  
of Common Stock  
Beneficially Owned(2)   

Percentage of Shares  
of Common Stock  
Beneficially Owned (6)   

15,481   

13,543 (4)     

1,667 (5)     

436,648 (1)     
60,063 (1)     
386,117 (1)     
13,334 (1)     
13,334 (1)     
11,286 (1)     

920,782 (1)     

287,469 (1)     

1,208,251   

8.1 % 
1.2 % 
7.4 % 
*   
*   
*   

16.1 % 

5.4 % 

20.1 % 

(1)  Includes shares which individuals shown above have the right to acquire as of May 8, 2015, or within 60 days thereafter, pursuant to 

outstanding stock options and/or warrants as follows: Mr. Shelton—379,445 shares; Mr. Stefanovich—60,063 shares; Mr. Rathmann—
225,832 of which 65,568 are individually owned by Mr. Rathmann and 160,264 are owned by GBR Investments,LLC of which Mr. 
Rathmann is the manager; Mr. Zecchini—13,334; Dr. Mandalam—13,334 shares; Mr. Berman—7,118 shares; Cranshire Capital—287,469 
shares. 

(2)  The number and percentage of shares beneficially owned is determined in accordance with Rule 13d-3 of the Securities Exchange Act of 

1934, and the information is not necessarily indicative of beneficial ownership for any other purpose. Under such rule, beneficial ownership 
includes any shares as to which the selling security holder has sole or shared voting power or investment power and also any shares which 
the selling security holder has the right to acquire within 60 days. 

(3)  Cranshire Capital Master Fund, Ltd. address is 3100 Dundee Road, Suite 703, Northbrook, IL 60062. 

(4)  GBR Investments, LLC of which Mr. Rathmann is the manager. 

(5)  Mrs. Richard Berman, spouse of Mr. Berman. 

(6)  Includes preferred stock converted on 2.5-to-1 basis. 

Equity Compensation Plan Information  

We currently maintain three equity compensation plans, referred to as the 2002 Stock Incentive Plan (the “2002 Plan”), the 2009 Stock 
Incentive Plan (the “2009 Plan”) and the 2011 Stock Incentive Plan (the “2011 Plan”). Our Compensation Committee is responsible for making, 
reviewing and recommending grants of options and other awards under these plans which are approved by the Board.  

The 2002 Plan, which was approved by our stockholders in October 2002, allows for the grant of options to purchase up to 41,667 shares 
of the Company’s common stock. The 2002 Plan provides for the granting of options to purchase shares of our common stock at prices not less 
than the fair market value of the stock at the date of grant and generally expire 10 years after the date of grant. The stock options are subject to 
vesting requirements, generally three or four years. The 2002 Plan also provides for the granting of restricted shares of common stock subject to 
vesting requirements. As of June 30, 2013, no shares are available for future issuances as the 2002 Plan has expired.  

49 

    
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
  
    
    
    
    
    
    
    
    
  
    
    
    
    
    
    
    
    
    
    
    
    
    
    
    
  
    
    
    
    
    
    
    
    
    
The 2009 Plan, which was approved by our stockholders at our 2009 Annual Meeting of Stockholders held on October 9, 2009, provides 
for  the  grant  of  stock-based  incentives.  The  2009  Plan  allows  for  the  grant  of  up  to  100,000  shares  of  our  common  stock  for  awards  to  our 
officers,  directors,  employees  and  consultants.  The  2009  Plan  provides  for  the  grant  of  incentive  stock  options,  nonqualified  stock  options, 
restricted stock  rights,  restricted stock, performance  share units, performance  shares, performance  cash awards, stock  appreciation rights, and 
stock  grant  awards.  The  2009  Plan  also  permits  the  grant  of  awards  that  qualify  for  the  “performance-based  compensation”  exception  to  the 
$1,000,000 limitation on the deduction of compensation imposed by Section 162(m) of the Code. As of May 8, 2015, a total of 25,314 shares of 
our common stock remained available for future grants under the 2009 Plan.  

The 2011 Plan, as amended, which was approved by our stockholders at our 2011 Annual Meeting of Stockholders held on September 22, 
2011  and,  with  respect  to  the  amendments,  at  our  2012,  2013,  and  2014  Annual  Meeting  of  Stockholders  held  on  September  13,  2012, 
September 6, 2013 and August 29, 2014, respectively, provides for the grant of stock-based incentives. The 2011 Plan allows for the grant of up 
to 1,158,334 shares of our common stock for awards to our officers, directors, employees and consultants. The 2011 Plan provides for the grant 
of  incentive  stock  options,  nonqualified  stock  options,  restricted  stock  rights,  restricted  stock,  performance  share  units,  performance  shares, 
performance cash awards, stock appreciation rights, and stock grant awards. The 2011 Plan also permits the grant of awards that qualify for the 
“performance-based compensation” exception to the $1,000,000 limitation on the deduction of compensation imposed by Section 162(m) of the 
Code. Awards may be granted under the 2011 Plan until September 21, 2021 or until all shares available for Awards under the 2011 Plan have 
been purchased or acquired unless the stockholders of the Company vote to approve an extension of the 2011 Plan prior to such expiration date. 
As of May 8, 2015, a total of 30,190 shares remained available for future grants under the 2011 Plan.  

In  addition  to  the  stock  options  issued  pursuant  to  the  Company’s  three  stock  incentive  plans,  the  Company  has  granted  warrants  to 
employees, officers, non-employee directors and consultants. The warrants are generally not subject to vesting requirements and have ten-year 
terms.  

Securities Authorized for Issuance Under Equity Compensation Plans  

The following table sets forth certain information as of March 31, 2015 concerning the Company’s common stock that may be issued upon 
the exercise of options or warrants or pursuant to purchases of stock under the 2002 Plan, the 2009 Plan, the 2011 Plan and other stock based 
compensation:  

Plan Category 
Equity compensation plans approved by stockholders 
Equity compensation plans not approved by stockholders(1) 

(a)  
 Number of Securities 
 to be Issued Upon the 
 Exercise of  
 Outstanding Options 
 and Warrants 

(b)  
 Weighted-Average 
 Exercise Price of  
 Outstanding  
 Options and  
 Warrants 

(c)  
Available for Future  
Issuance Under Equity  
Compensation Plans  
(Excluding Securities  
Reflected in Column (a))   
182,796   
N/A   

5.16       
6.36       

1,027,564     $ 
788,086     $ 

1,815,650       

182,796   

(1)  During November 5, 2012 through December 18, 2014, a total of 766,181options outstanding were granted to employees outside of an 
option plan of which 671,043 shares were issued to Mr. Shelton. In the past the Company has issued warrants to purchase 27,285 shares 
of common stock in exchange for services provided to the Company, of which warrants to purchase 21,905 shares of common stock are 
outstanding  and  expire  through  June  2019.  The  exercise  prices  ranged  from  $33.60  to  $129.60  and  generally  vested  upon  issuance. 
Fifteen consultants and former officers and directors received warrants to purchase 27,285 shares of common stock in this manner. 

The table above  excludes options  to purchase 465,625  and 20,834 shares of common stock  granted on May 7, 2015 to employees and 
members of the board of director’s, respectively, with an exercise price of $7.80 per share, of which 355,000 shares were issued outside of a 
plan. The exercise price for the shares of common stock pursuant to the option is equal to the fair market value of the Company’s common stock 
on the date of grant.  

50 

   
   
   
   
   
   
   
   
   
  
  
    
    
    
    
  
    
        
        
    
  
    
        
Item 13.   Certain Relationships and Related Transactions, and Director Independence.  

The Company has established policies and other procedures regarding approval of transactions between the Company and any employee, 
officer,  director,  and  certain  of  their  family  members  and  other  related  persons,  including  those  required  to  be  reported  under  Item 404  of 
Regulation S-K. These policies and procedures are generally not in writing, but are evidenced by long standing principles set forth in our Code 
of Conduct or adhered to by our Board. As set forth in the Audit Committee Charter, the Audit Committee reviews and approves all related-party 
transactions after reviewing such transaction for potential conflicts of interests and improprieties. Accordingly, all such related-party transactions 
are submitted to the Audit Committee for ongoing review and oversight. Generally speaking, we enter into related-party transactions only on 
terms that we believe are at least as favorable to our company as those that we could obtain from an unrelated third party.  

The  following  related-party  transaction  were  approved  or  ratified  by  at  least  two  independent  directors  and  future  material  affiliated 
transactions will be approved by a majority of the independent directors who do not have an interest in the transaction and who had access, at the 
issuer’s expense, to issuer’s or independent legal counsel.  

On  May  9,  2013,  Richard  Rathmann,  Director,  invested  $100,000  in  the  Bridge  Notes  offered  by  the  Company  to  certain  accredited 
investors.  For information on terms related to the Bridge Notes, refer to Note 8 “Convertible Debentures Payable” in the Company’s Form 10-K 
for  the  period  ended March  31,  2013 filed  with  the  SEC on  June  25,  2013.   In  addition,  on  July  12,  2013,  GBR  Investments,  LLC,  invested 
$100,000 in the Bridge Notes offered by the Company to certain accredited investors and also received a warrant to purchase 33,334 shares of 
common  stock  at  an  exercise  price  of  $3.00  per  share,  pursuant  to  the  terms  of  such  offering.   Richard  Rathmann  is  the  Manager  of  GBR 
investments, LLC and is considered an indirect beneficial owner of these securities.  

During the year ended March 31, 2014, the Company issued to certain accredited investors various unsecured promissory notes with the 
terms  as  described  under  Note  8  in  the  accompanying  March  31,  2015  consolidated  financial  statements.  These  unsecured  promissory  notes 
included  $120,000  of  the  5%  Bridge  Notes  issued  to  Jerrell  Shelton,  the  Company’s  Chief  Executive  Officer,  $100,000  of  the  Bridge  Notes 
issued to Richard Rathmann, a member of the Board of Directors of the Company, $200,000 of the Bridge Notes and $100,000 of the 5% Bridge 
Notes  issued  to  GBR  Investments,  LLC,  of  which  Richard  Rathmann,  is  the  manager.  In  May  2014,  both  note  holders  elected  to  convert  all 
principal  and  interest  into  a  newly  established  Class  A  Convertible  Preferred  Stock  and  warrants  to  purchase  common  stock  of  Cryoport  as 
further described in Note 11 in the accompanying consolidated financial statements. In November 2014, both Mr. Shelton and GBR Investments, 
LLC participated in the Class A convertible preferred stock offering and the Company issued 4,167 shares of Class A convertible preferred stock 
each in exchange for an aggregate amount of $100,000.  

As  of  March  31,  2015,  we  had  an  aggregate  principal  balance  of  $1.3  million,  in  unsecured  indebtedness  owed  to  five  related  parties, 
including four former members of the Board of Directors, representing working capital advances made to us from February 2001 through March 
2005. Accrued interest related to these notes amounted to $4,600 as of March 31, 2015.  

In March 2015, we entered into definitive agreements relating to the exchange or amendment of the notes evidencing such working capital 
advances.  Three  of  the  notes  issued  to  Patrick  Mullins,  M.D.,  Maryl  Petreccia  and  Jeffrey  Dell,  M.D.,  which  as  of  March  31,  2015  had 
outstanding  principal  balances  of  $448,200,  $266,700  and  $208,900,  respectively,  were  amended  and  the  holders  received  warrants  for  the 
purchase 37,347, 22,224, and 17,412 shares, respectively, of our common stock at an exercise price of $6.00 per share, exercisable on March 2, 
2015 and expiring on March 1, 2020, and warrants to purchase 834, 417, and 417 shares, respectively, of the our common stock, exercisable on 
March 2, 2015 and expiring on March 1, 2020, to reimburse the three note holders for any fees or other expenses incurred in connection with this 
transaction. The notes, as amended, require interest payments on a calendar quarterly basis and all outstanding principal and accrued interest on 
the  maturity  date,  which  is  the  earlier  to  occur  of  (i)  March  1,  2016,  (ii)  the  sale  of  all  or  substantially  all  of  our  assets,  or  (iii)  the  merger, 
consolidation or other similar reorganization of the Company or an affiliate of our Company with another entity. Under the terms of such note, 
upon the closing of a public offering pursuant to an effective registration statement under the Securities Act of 1933, as amended, resulting in at 
least $5,000,000 of gross cash proceeds to the Company for the sale of shares of Common Stock or includes the sale of shares of Common Stock 
among the sale of other securities, the holder has the option to convert into the securities issued in such offering at a twenty percent (20%) to the 
price per  share  (or  per unit,  if applicable) of  the  securities  issued  by  the  Company in  such  offering.  The  securities  issued  to the  holder  upon 
conversion will be restricted securities.  

One note issued to Raymond Takahashi, M.D., was exchanged for (i) a new convertible promissory note with an original principal amount 
equal to the outstanding principal and interest of the original note, and (ii) a warrant to purchase 1,490 shares of the Company’s common stock at 
an exercise price of $6.00 per share, exercisable on February 20, 2015 and expiring on February 19, 2018. The new note, which as of March 31, 
2015 had an outstanding principal balance of $35,800, requires interest payments on a calendar quarterly basis and all outstanding principal and 
accrued interest on the maturity date, which is March 1, 2016. Under the terms of such note, upon the closing of a public offering pursuant to an 
effective  registration  statement  under  the  Securities  Act  of  1933,  as  amended,  resulting  in  at  least  $5,000,000  of  gross  cash  proceeds  to  the 
Company for the sale of shares of Common Stock or includes the sale of shares of Common Stock among the sale of other securities, the holder 
has the option to convert into the securities issued in such offering at a twenty percent (20%) to the price per share (or per unit, if applicable) of 
the securities issued by the Company in such offering. The securities issued to the holder upon conversion will be restricted securities.  

51 

    
   
   
   
   
   
   
   
   
  
One note issued to Marc Grossman, M.D., which as of March 31, 2015 had an outstanding principal balance of $298,500, as amended, 
now provides for interest at a rate of 6% per annum commencing on March 13, 2015; however, no interest payments will be due if no event of 
default occurs and if the Company (i) complies with its regular payment obligations, reimburses the payee for attorneys’ fees in connection with 
the negotiation of the Note Amendment, up to a maximum amount of $1,000, on the later of (A) March 13, 2015, or (B) three (3) days after 
receiving written notice from the payee of the amount of attorneys’ fees incurred by payee, and (iii) the Company immediately pays all unpaid 
amounts due and payable in full before the earlier of May 1, 2016 or at the same time that payee(s) of any other promissory note(s) with the 
Company that were issued in 2005 are paid in full before May 1, 2016, other than (Y) notes that are satisfied upon conversion into common 
stock, warrants or any other equity of the Company, or (Z) notes that have been paid in full before March 2, 2015. All principal and interest 
under  the  Original  Note,  as  amended  by  the  Note  Amendment,  will  be  due  and  shall  be  paid  on  May  1,  2016.  The  note  requires  monthly 
payments of $20,000, except for the month of June 2015, where the monthly payment is $72,000.  

SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE  

Section  16(a)  of  the  Exchange  Act  requires  the  Company’s  directors  and  executive  officers,  and  persons  who  own  more  than  10%  of  a 
registered class  of  the  Company’s  equity  securities,  to  file  with the  SEC  reports  of  beneficial  ownership  and  reports  of  changes in  beneficial 
ownership in the Company’s securities. Such directors, executive officers and 10% stockholders are also required to furnish the Company with 
copies of all Section 16(a) forms they file.  

Based solely on a review of the copies of such forms received by it, the Company believes that during fiscal 2015, all Section 16(a) filings 
applicable to its directors, officers, and 10% stockholders were filed on a timely basis, except that Jerrell Shelton had two late reports for two 
transactions,  Richard  Rathmann  had  two  late  reports  for  three  transactions,  Mandalam  Ramkumar  Ph.D.  had  two  late  reports  for  three 
transactions, Robert Stefanovich had one late report for one transaction, Ed Zecchini had one late report for two transactions.  

Item 14.   Principal Accountant Fees and Services  

Independent Registered Public Accounting Firms Fees  

The following table shows the fees that were billed to us for the audit and other services provided by KMJ Corbin & Company LLP (“KMJ”) 

for the Company’s fiscal 2015 and fiscal 2014.  

Audit Fees 
Audit-Related Fees 
Tax Fees 

2015  

2014  

  $ 

  $ 

76,300     $ 
19,775       
9,275       
105,350     $ 

69,325   
—  
7,100   
76,425   

The fees billed to us by KMJ during or related to the fiscal years ended March 31, 2015 and 2014 consist of audit fees, audit-related fees 

and tax fees, as follows:  

Audit Fees . Represents the aggregate fees billed to us for professional services rendered for the audit of our annual consolidated financial 

statements and for the reviews of our consolidated financial statements included in our Form 10-Q filings for each fiscal quarter.  

Audit-Related  Fees.  Represents  the  aggregate  fees  billed  to  us  for  assurance  and  related  services  that  are  reasonably  related  to  the 
performance of the audit and review of our consolidated financial statements that are not already reported in Audit Fees. These services include 
accounting consultations and attestation services that are not required by statute such as S-1 and S-8 filings.  

Tax Fees. Represents the aggregate fees billed to us for professional services rendered for tax returns, compliance and tax advice.  

All Other Fees. We did not incur any other fees to KMJ during the fiscal years ended March 31, 2015 and 2014.  

52 

    
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
    
  
    
    
  
Policy on Audit Committee Pre-Approval of Fees  

The Audit Committee must pre-approve all services to be performed for us by our independent auditors. Pre-approval is granted usually at 
regularly  scheduled  meetings  of  the  Audit  Committee.  If  unanticipated  items  arise  between  regularly  scheduled  meetings  of  the  Audit 
Committee, the  Audit  Committee has  delegated authority to the  chairman of  the  Audit  Committee to pre-approve services, in which case  the 
chairman  communicates  such  pre-approval  to  the  full  Audit  Committee  at  its  next  meeting.  The  Audit  Committee  also  may  approve  the 
additional unanticipated services by either convening a special meeting or acting by unanimous written consent. During the fiscal years ended 
March 31, 2015 and 2014, all services billed by KMJ were pre-approved by the Audit Committee in accordance with this policy.  

Item 15.   Exhibits and Financial Statement Schedules  

(a)(1) Consolidated Financial Statements:  

PART IV  

Report of Independent Registered Public Accounting Firm 
Consolidated Balance Sheets as of March 31, 2015 and 2014 
Consolidated Statements of Operations for the years ended March 31, 2015 and 2014 
Consolidated Statements of Stockholders’ (Deficit) Equity for the years ended March 31, 2015 and 2014 
Consolidated Statements of Cash Flows for the years ended March 31, 2015 and 2014 
Notes to Consolidated Financial Statements 

Page  

F-2 
F-3 
F-4 
F-5 
F-6 
F-7 

(a)(2)  Financial  Statement  Schedules:  All  financial  statement  schedules  are  omitted  because  they  are  not  applicable  or  the  required 

information is included in the Consolidated Financial Statements or notes thereto.  

(a)(3) Exhibits.  

Exhibit  
No.  

Exhibits  

Description  

3.1 

  Amended and Restated Articles of Incorporation of the Company, as amended.  Incorporated by reference to Exhibit 3.1 to the 

Company’s Quarterly Report on Form 10-Q for the Quarter Ended September 30, 2012. 

3.2 

  Amended and Restated Bylaws of the Company.  Incorporated by reference to Exhibit 3.2 of the Company’s Current Report on 

Form 8-K dated October 23, 2012. 

3.3 

  Cryoport Systems, Inc. 2002 Stock Incentive Plan adopted by the Board of Directors on October 1, 2002.  Incorporated by reference 

to Exhibit 3.13 to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

3.4 

  Amended and Restated Certificate of Designation of Class A Preferred Stock. Incorporated by reference to Exhibit 3.1 of the 

Company’s Current Report on Form 8-K dated March 26, 2015. 

3.5 

  Certificate of Designation of Class B Preferred Stock. Incorporated by reference to Exhibit 3.1 of the Company’s Current Report on 

Form 8-K dated February 20, 2015. 

3.6 

  Amendment to Certificate of Designation of Class B Preferred Stock.  Incorporated by reference to Cryoport’s Amendment No. 1 to 

Registration Statement on Form S-1 dated April 17, 2015 and referred to as Exhibit 3.6. 

3.7+ 

  Certificate of Change filed with the Nevada Secretary of State on May 12, 2015. 

4.1 

  Form of Common Stock Purchase Warrant dated September 28, 2007. Incorporated by reference to Cryoport’s Registration 

Statement on Form SB-2 dated November 9, 2007. 

4.2 

  Common Stock Purchase Warrant dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 

June 9, 2008. 

4.3 

  Common Stock Purchase Warrant dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 

June 9, 2008. 

53 

   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
Exhibit  
No.  

Description  

4.4 

   Form of Warrant and Warrant Certificate in connection with the February 25, 2010 public offering. Incorporated by reference to 

Cryoport’s Amendment No. 5 to Form S-1/A Registration Statement dated February 9, 2010. 

4.5 

   Form of Securities Purchase Agreement in connection with the August to October 2010 private placement. Incorporated by 

reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.6 

   Form of First Amendment to Security Purchase Agreement in connection with the August to October 2010 private placement. 

Incorporated by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.7 

   Form of Securities Purchase Agreement (Continuation of the Placement) in connection with the August to October 2010 private 

placement. Incorporated by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.8 

   Registration Rights Agreement in connection with the August to October 2010 private placement. Incorporated by reference to 

Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.9 

   Form of Joinder to Registration Rights Agreement in connection with the August to October 2010 private placement. Incorporated 

by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.10 

   Form of Securities Purchase Agreement in connection with the February 2011 private placement. Incorporated by reference to 

Cryoport’s Registration Statement on Form S-1 dated April 1, 2011. 

4.11 

   Form of Registration Rights Agreement in connection with the February 2011 private placement. Incorporated by reference to 

Cryoport’s Registration Statement on Form S-1 dated April 1, 2011.  

4.12 

   Form of Warrant in connection with the August to October 2010 private placement. Incorporated by reference to Cryoport’s 

Registration Statement on Form S-1/A dated April 22, 2011. 

4.13 

   Form of Warrant in connection with the February 2011 private placement. Incorporated by reference to Cryoport’s Registration 

Statement on Form S-1/A dated April 22, 2011. 

4.14 

   Form of Securities Purchase Agreement. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC 

on February 24, 2012. 

4.15 

   Form of Registration Rights Agreement. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC 

on February 24, 2012. 

4.16 

4.17 

   Form of Warrant. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC on February 24, 2012. 

   Form of Warrant issued with Convertible Promissory Notes.  Incorporated by reference to Exhibit 4.20 of Cryoport’s Quarterly 

Report on Form 10-Q for the Quarter Ended September 30, 2013. 

4.18 

   Form of Warrant issued upon Conversion of Convertible Promissory Notes.  Incorporated by reference to Exhibit 4.21 of 

Cryoport’s Quarterly Report on Form 10-Q for the Quarter Ended September 30, 2013. 

4.19 

   Form of Warrant Issued to Placement Agents.  Incorporated by reference to Exhibit 4.22 of Cryoport’s Quarterly Report on Form 

10-Q for the Quarter Ended September 30, 2013. 

4.20 

   Form of Warrant issued with Convertible Promissory Notes (5% Bridge Notes).  Incorporated by reference to Exhibit 4.23 of 

Cryoport’s Quarterly Report on Form 10-Q for the Quarter Ended December 31, 2013. 

4.21 

   Form of Warrant issued in connection with the May 2014 private placement. Incorporated by reference to Exhibit 4.24 of 

Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2014. 

4.22 

   Warrant to Purchase Common Stock. Incorporated by reference to Exhibit 4.1 of the Company’s Current Report on Form 8-K dated 

December 9, 2014. 

54 

   
   
  
  
  
  
  
  
     
  
     
  
     
  
     
  
     
  
     
  
     
   
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
Exhibit  
No.  

Description  

4.23 

  Warrant to Purchase Common Stock. Incorporated by reference to Exhibit 4.1 of the Company’s Current Report on Form 8-K dated 

February 20, 2015. 

4.24 

  Form of Warrant issued in connection with the Exchange and Investment Agreement. Incorporated by reference to Exhibit 4.1 of 

the Company’s Current Report on Form 8-K dated March 9, 2015. 

4.25 

  Form of March Warrant issued in connection with the Investment Agreement. Incorporated by reference to Exhibit 4.2 of the 

Company’s Current Report on Form 8-K dated March 9, 2015. 

4.26 

  Form of March Fee Warrant issued in connection with the Investment Agreement. Incorporated by reference to Exhibit 4.3 of the 

Company’s Current Report on Form 8-K dated March 9, 2015. 

10.1.1 

  Commercial Promissory Note between Cryoport, Inc. and D. Petreccia executed on August 26, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.2 

  Commercial Promissory Note between Cryoport, Inc. and J. Dell executed on September 1, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.3 

  Commercial Promissory Note between Cryoport, Inc. and P. Mullens executed on September 2, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.4 

  Commercial Promissory Note between Cryoport, Inc. and R. Takahashi executed on August 25, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.2.1 

  Lease Agreement dated June 26, 2007 between CryoPort, Inc. and Viking Investors—Barents Sea LLC. Incorporated by reference 

to CryoPort’s Quarterly Report on Form 10-QSB for the quarter ended June 30, 2007 and referred to as Exhibit 10.5 

10.2.2 

  Second Amendment To Lease: Renewal dated August 24, 2009, between CryoPort, Inc. and Viking Inventors-Barents Sea LLC. 

Incorporated by reference to Cryoport’s Amendment No. 1 to Form S-1/A Registration Statement dated January 12, 2010. 

10.2.3 

  Third Amendment to Lease: Renewal dated June 8, 2010 between Viking Investors Barents Sea, LLC. Incorporated by reference to 

Exhibit 10.5.3 to Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2013. 

10.3 

  Securities Purchase Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form 

SB-2 dated November 9, 2007 and referred to as Exhibit 10.6. 

10.4 

  Registration Rights Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form 

SB-2 dated November 9, 2007 and referred to as Exhibit 10.7. 

10.5 

  Security Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form SB-2 dated 

November 9, 2007 and referred to as Exhibit 10.8. 

10.6 

  Securities Purchase Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 

June 9, 2008 and referred to as Exhibit 10.10. 

10.7 

  Registration Rights Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 

June 9, 2008 and referred to as Exhibit 10.11. 

10.8 

  Waiver dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 2008 and referred 

to as Exhibit 10.12. 

55 

   
   
  
  
  
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
Exhibit  
No.  

Description  

10.9 

  Security Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 2008 

and referred to as Exhibit 10.13. 

10.10 

  Consent, Waiver and Agreement with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified Strategy 

Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. and its subsidiary dated July 30, 2009. Incorporated by 
reference to Cryoport’s Current Report on Form 8-K dated July 29, 2009 and referred to as Exhibit 10.15. 

10.11.1 

  Master Consulting and Engineering Services Agreement dated October 9, 2007 with KLATU Networks, LLC and CryoPort, Inc. 

Incorporated by reference to Cryoport, Inc.’s Registration Statement on Form S-8 dated March 25, 2009 and referred to as Exhibit 
10.2. 

10.11.2 

  First Amendment to Master Consulting and Engineering Services Agreement dated as of April 23, 2009, between CryoPort, Inc. 

and KLATU Networks, LLC. Incorporated by reference to Cryoport’s Registration Statement on Form S-1/A dated December 17, 
2010 and referred to as Exhibit 10.32. 

10.11.3 

  Second Amendment to Master Consulting and Engineering Services Agreement dated as of November 1, 2010, between CryoPort, 
Inc. and KLATU Networks, LLC. Incorporated by reference to Cryoport’s Registration Statement on Form S-1/A dated December 
17, 2010 and referred to as Exhibit 10.33. 

10.12 

  Stock Option Agreement ISO under the 2002 Stock Incentive Plan of Cryoport Systems, Inc. Incorporated by reference to Exhibit 

3.14 to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

10.13 

  Stock Option Agreement NSO under the 2002 Stock Incentive Plan of Cryoport Systems, Inc. Incorporated by reference to Exhibit 

3.15 to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

10.14 

  2009 Stock Incentive Plan of the Company.  Incorporated by reference to Exhibit 10.21 of the Company’s Current Report on Form 

8-K dated October 15, 2009 and referred to as Exhibit 10.21. 

10.15 

  Form Incentive Stock Option Award Agreement under the 2009 Stock Incentive Plan of the Company. Incorporated by reference to 

Exhibit 10.22 of the Company’s Current Report on Form 8-K dated October 9, 2009. 

10.16 

  Form of Non-Qualified Stock Option Award Agreement under the 2009 Stock Incentive Plan of the Company. Incorporated by 

reference to Exhibit 10.25 of the Company’s Registration Statement on Form S-8 dated April 27, 2010. 

10.17 

  2011 Stock Incentive Plan (as amended and restated).  Incorporated by reference to Exhibit B of the Company’s Definitive Proxy 

Statement on Schedule 14A filed with the SEC on July 30, 2012. 

10.18 

  Form of Stock Option Award Agreement. Incorporated by reference to Exhibit 10.37 to Cryoport’s Current Report on Form 8-K 

filed with the SEC on September 27, 2011. 

10.19 

  Form of Non-Qualified Stock Option Award Agreement. Incorporated by reference to Exhibit 10.38 to Cryoport’s Current Report 

on Form 8-K filed with the SEC on September 27, 2011. 

10.20 

  Form of Convertible Promissory Note. Incorporated by reference to Exhibit 10.24 to Cryoport’s Annual Report on Form 10-K filed 

with the SEC on June 25, 2013. 

10.21 

  Form of Amendment to Convertible Promissory Note. Incorporated by reference to Exhibit 10.25 to Cryoport’s Annual Report on 

Form 10-K filed with the SEC on June 25, 2013. 

10.22 

  Form of Convertible Promissory Note. Incorporated by reference to Exhibit 10.26 to Cryoport’s Annual Report on Form 10-K filed 

with the SEC on June 25, 2013. 

10.23* 

  Employment Agreement between the Company and Jerrell Shelton.  Incorporated by reference to the Company’s Current Report on 

Form 8-K filed on November 6, 2012 and referred to as Exhibit 10.45. 

10.24* 

  Stock Option Agreement dated November 5, 2012 between the Company and Jerrell Shelton. Incorporated by reference to Exhibit 

10.28 to Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2013. 

56 

   
   
  
  
  
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
Exhibit  
No.  

10.25# 

  Master Agreement between the Company and Federal Express Corporation dated January 1, 2013.  Incorporated by reference to the 
Company’s Current Report on Form 8-K filed on January 8, 2013 and referred to as Exhibit 10.1. 

Description  

10.26* 

   Employment Agreement dated June 28, 2013 with Jerrell Shelton.  Incorporated by reference to Exhibit 10.30 to Cryoport’s 

Current Report on Form 8-K filed with the SEC on July 3, 2013. 

10.27 

   Form of Convertible Promissory Notes issued with Warrants.  Incorporated by reference to Exhibit 10.31 to Cryoport’s Quarterly 

Report on Form 10-Q for the Quarter Ended September 30, 2013. 

10.28 

   Form of Letter of Tender and Exchange.  Incorporated by reference to Exhibit 10.32 to Cryoport’s Quarterly Report on Form 10-Q 

for the Quarter Ended September 30, 2013. 

10.29 

   Form of Convertible Promissory Note (5% Bridge Note) issued with Warrants.  Incorporated by reference to Exhibit 10.33 to 

Cryoport’s Quarterly Report on Form 10-Q for the Quarter Ended December 31, 2013. 

10.30 

   Form of Subscription Agreement in connection with the May 2014 private placement. Incorporated by reference to Exhibit 10.34 to 

Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2014. 

10.31 

   Form of Election to Convert in connection with the May 2014 private placement. Incorporated by reference to Exhibit 10.35 to 

Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2014. 

10.32 

   Form of Indemnification Agreement. Incorporated by reference to Exhibit 10.1 to Cryoport’s Current Report on Form 8-K filed 

with the SEC on July 16, 2014. 

10.33 

   Subscription Agreement and Letter of Investment Intent. Incorporated by reference to Exhibit 10.1 to Cryoport’s Current Report on 

Form 8-K filed with the SEC on December 9, 2014. 

10.34 

   2014 Series Secured Promissory Note. Incorporated by reference to Exhibit 10.2 to Cryoport’s Current Report on Form 8-K filed 

with the SEC on December 9, 2014. 

10.35 

   Security Agreement. Incorporated by reference to Exhibit 10.3 to Cryoport’s Current Report on Form 8-K filed with the SEC on 

December 9, 2014. 

10.36 

   Subscription Agreement and Letter of Investment Intent. Incorporated by reference to Exhibit 10.1 to Cryoport’s Current Report on 

Form 8-K filed with the SEC on February 20, 2015. 

10.37 

   Form of Note Exchange Agreement and Letter of Investment Intent, dated February 19, 2015. Incorporated by reference to Exhibit 

10.1 to Cryoport’s Current Report on Form 8-K filed with the SEC on March 9, 2015. 

10.38 

   Form of Exchange Note issued in connection with the Exchange and Investment Agreement. Incorporated by reference to Exhibit 

10.2 to Cryoport’s Current Report on Form 8-K filed with the SEC on March 9, 2015. 

10.39 

   Form of Letter of Investment Intent, dated March 2, 2015. Incorporated by reference to Exhibit 10.3 to Cryoport’s Current Report 

on Form 8-K filed with the SEC on March 9, 2015. 

10.40 

   Form of Amended and Restate Note issued in connection with the Exchange and Investment Agreement. Incorporated by reference 

to Exhibit 10.4 to Cryoport’s Current Report on Form 8-K filed with the SEC on March 9, 2015. 

10.41 

   Amendment to Simple Interest Commercial Promissory Note, dated March 2, 2015. Incorporated by reference to Exhibit 10.5 to 

Cryoport’s Current Report on Form 8-K filed with the SEC on March 9, 2015 

10.42*+ 

   Stock Option Agreement dated December 18, 2014 between the Company and Jerrell Shelton. 

21+ 

   Subsidiaries of Registrant. 

23.1+ 

   Consent of Independent Registered Public Accounting Firm—KMJ Corbin & Company LLP. 

57 

   
   
  
  
  
  
  
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
Exhibit  
No.  

Description  

31.1+ 

  Certification of Principal Executive Officer, pursuant to Rule 13a-14(a)/15d-14(a) of the Securities Exchange Act of 1934 

31.2+ 

  Certification of Principal Financial Officer, pursuant to Rule 13a-14(a)/15d-14(a) of the Securities Exchange Act of 1934 

32.1+ 

  Certification of Principal Executive Officer, pursuant to Rule 13a-14(b)/15d-14(b) of the Securities Exchange Act of 1934 and 

18 U.S.C. Section 1350. 

32.2+ 

  Certification of Principal Financial Officer, pursuant to Rule 13a-14(b)/15d-14(b) of the Securities Exchange Act of 1934 and 

18 U.S.C. Section 1350. 

101.INS+    XBRL Instance Document. 

101.SCH+    XBRL Taxonomy Extension Schema Document. 

101.CAL+   XBRL Taxonomy Extension Calculation Linkbase Document. 

101.DEF+    XBRL Taxonomy Extension Definition Linkbase Document. 

101.LAB+   XBRL Taxonomy Extension Label Linkbase Document. 

101.PRE+    XBRL Taxonomy Extension Presentation Linkbase Document. 

* 

# 

Indicates a management contract or compensatory plan or arrangement. 

Confidential portions omitted and filed separately with the U.S. Securities and Exchange Commission pursuant to Rule 24b-2 promulgated 
under the Securities Exchange Act of 1934, as amended. 

+ 

Filed herewith. 

58 

   
   
   
   
   
   
  
  
  
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this Annual 

Report on Form 10-K to be signed on its behalf by the undersigned, thereunto duly authorized.  

SIGNATURES  

Cryoport, Inc. 

By: /s/ JERRELL W. SHELTON 

   Jerrell W. Shelton 
   Chief Executive Officer and Director 

Date: May 19, 2015  

Pursuant to  the requirements  of  the Securities  Exchange  Act  of  1934,  this  Annual  Report on Form 10-K  has been signed below  by  the 

following persons on behalf of the Registrant and in the capacities and on the dates indicated:  

Signature   

/s/ JERRELL W. SHELTON  

Jerrell W. Shelton  

/s/ ROBERT S. STEFANOVICH  

Robert S. Stefanovich  

/s/ RICHARD G. RATHMANN  

Richard G. Rathmann  

/s/ EDWARD ZECCHINI  

Edward Zecchini  

/s/ RAMKUMAR MANDALAM, PH.D.  

Ramkumar Mandalam Ph.D.  

/s/ RICHARD BERMAN  

Richard Berman  

Title   

Chief Executive Officer and Director  
(Principal Executive Officer)  

Chief Financial Officer  
(Principal Financial and Accounting Officer)  

Director 

Director 

Director 

Director 

59 

Date   

May 19, 2015 

May 19, 2015 

May 19, 2015 

May 19, 2015 

May 19, 2015 

May 19, 2015 

   
   
   
   
   
   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
     
  
  
  
  
  
  
     
  
  
  
  
  
  
     
  
  
  
  
  
  
  
  
  
  
  
  
  
  
     
  
  
  
  
  
  
  
  
  
  
  
Cryoport, Inc. and Subsidiary  

Consolidated Financial Statements  

As of March 31, 2015 and 2014  

For Each of the Two Years Ended March 31, 2015  

     
   
   
   
   
  
  
Cryoport, Inc. and Subsidiary  

Consolidated Financial Statements  

INDEX TO FINANCIAL STATEMENTS  

Report of Independent Registered Public Accounting Firm 

Consolidated Balance Sheets as of March 31, 2015 and 2014 
Consolidated Statements of Operations for the years ended March 31, 2015 and 2014 
Consolidated Statements of Stockholders’ (Deficit) Equity for the years ended March 31, 2015 and 2014 
Consolidated Statements of Cash Flows for the years ended March 31, 2015 and 2014 
Notes to Consolidated Financial Statements 

Page   
F-2 
F-3 
F-4 
F-5 
F-6 
F-7 

F- 1 

   
   
   
   
   
  
  
Report of Independent Registered Public Accounting Firm  

The Board of Directors and  
Stockholders of Cryoport, Inc.  

We have audited the accompanying consolidated balance sheets of CryoPort, Inc. (the “Company”) as of March 31, 2015 and 2014, and the 
related consolidated statements of operations, stockholders’ (deficit) equity and cash flows for each of the years in the two-year period ended 
March 31, 2015. These consolidated financial statements are the responsibility of the Company’s management. Our responsibility is to express 
an opinion on these consolidated financial statements based on our audits.  

We  conducted  our  audits  in  accordance  with  the  standards  of  the  Public  Company  Accounting  Oversight  Board  (United  States).  Those 
standards require that we plan and perform the audits to obtain reasonable assurance about whether the consolidated financial statements are free 
of  material  misstatement.  An  audit  includes  examining,  on  a  test  basis,  evidence  supporting  the  amounts  and  disclosures  in  the  consolidated 
financial  statements.  The  Company  is  not  required  to  have,  nor  were  we  engaged  to  perform,  an  audit  of  its  internal  control  over  financial 
reporting.  Our  audits  included  consideration  of  internal  control  over  financial  reporting  as  a  basis  for  designing  audit  procedures  that  are 
appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the Company’s internal control over 
financial reporting. Accordingly, we express no such opinion.  An audit also includes assessing the accounting principles used and significant 
estimates  made  by  management,  as  well  as  evaluating  the  overall  consolidated  financial  statement  presentation.  We  believe  that  our  audits 
provide a reasonable basis for our opinion.  

In  our  opinion,  the  consolidated  financial  statements  referred  to  above  present  fairly,  in  all  material  respects,  the  consolidated  financial 
position of CryoPort, Inc. at March 31, 2015 and 2014, and the results of its operations and its cash flows for each of the years in the two-year 
period ended March 31, 2015 in conformity with accounting principles generally accepted in the United States of America.  

The  accompanying  consolidated  financial  statements  have  been  prepared  assuming  the  Company  will  continue  as  a  going  concern.  As 
described  in Note  1 to  the consolidated financial statements,  the  Company  has incurred  recurring  operating  losses  and  has had negative cash 
flows from operations since inception. Although the Company has cash and cash equivalents of $1.4 million at March 31, 2015, management has 
estimated that cash on hand, which include proceeds from Class B convertible preferred stock received subsequent to the fourth quarter of fiscal 
2015, will only be sufficient to allow the Company to continue its operations into the third quarter of fiscal 2016. These matters raise substantial 
doubt about the Company’s ability to continue as a going concern. Management’s plans in regard to these matters are also described in Note 1. 
The consolidated financial statements do not include any adjustments that might result from the outcome of this uncertainty.  

/s/ KMJ Corbin & Company LLP  

Costa Mesa, California  
May 19, 2015  

F- 2 

    
   
   
   
   
   
   
   
  
Cryoport, Inc. and Subsidiary  

Consolidated Balance Sheets  

Current Assets: 

ASSETS 

Cash and cash equivalents 
Accounts receivable, net of allowance for doubtful accounts of $12,200 and $24,600, 

  $ 

1,405,186     $ 

369,581   

March 31,  

2015  

2014  

respectively 

Inventories 
Other current assets 

Total current assets 

Property and equipment, net 
Intangible assets, net 
Deposits and other assets 

Total assets 

Current Liabilities: 

LIABILITIES AND STOCKHOLDERS’ DEFICIT 

Accounts payable and other accrued expenses 
Accrued compensation and related expenses 
Notes payable and accrued interest, net of discount of $221,400 at March 31, 2015 
Convertible debentures payable and accrued interest, net of discount of $184,800 at March 31, 

2014 

Related-party notes payable and accrued interest, net of discount of $259,600 at March 31, 

2015 

Total current liabilities 

Related-party notes payable, net of current portion 

Total liabilities 

Commitments and contingencies 
Stockholders’ (Deficit) Equity: 

  $ 

  $ 

589,699       
69,680       
97,337       
2,161,902       
307,926       
136,821       
—      
2,606,649     $ 

515,825   
29,703   
196,505   
1,111,614   
408,892   
180,086   
9,358   
1,709,950   

758,696     $ 
725,712       
535,507       

579,678   
454,288   
—  

—      

1,622,359   

976,581       
2,996,496       
26,452       
3,022,948       

1,358,120   
4,014,445   
—  
4,014,445   

Preferred stock, $0.001 par value; 2,500,000 shares authorized: 

Class A convertible preferred stock, $0.001 par value; 800,000 shares authorized; 454,750 
and 0 shares issued and outstanding at March 31, 2015 and 2014, respectively (aggregate 
liquidation preference of $5,758,485 at March 31, 2015) 

Class B convertible preferred stock, $0.001 par value; 585,000 shares authorized; 161,709 
and 0 shares issued and outstanding at March 31, 2015 and 2014, respectively (aggregate 
liquidation preference of $1,944,351 at March 31, 2015) 

455       

162       

—  

—  

Common stock, $0.001 par value; 20,833,333 shares authorized; 5,025,577 and 4,998,330 

issued and outstanding at March 31, 2015 and 2014, respectively 

Additional paid-in capital 
Accumulated deficit 

Total stockholders’ deficit 

Total liabilities and stockholders’ deficit 

5,026       
97,346,137       
(97,768,079 )     
(416,299 )     
2,606,649     $ 

4,999   
83,567,380   
(85,876,874 ) 
(2,304,495 ) 
1,709,950   

  $ 

See accompanying notes to consolidated financial statements.  

F- 3 

    
   
   
   
   
  
  
  
  
  
  
    
  
    
        
    
    
        
    
    
    
    
    
    
    
    
  
  
  
    
  
  
    
  
  
    
  
  
    
    
        
    
    
    
    
    
    
    
    
  
  
  
    
  
  
    
    
        
    
    
        
    
    
        
    
    
    
    
    
    
    
Cryoport, Inc. and Subsidiary  

Consolidated Statements of Operations  

Revenues 
Cost of revenues 
Gross margin 
Operating costs and expenses: 

Selling, general and administrative 
Research and development 

Total operating costs and expenses 
Loss from operations 
Other (expense) income: 

Debt conversion expense 
Interest expense 
Other expense, net 
Change in fair value of derivatives 
Loss before provision for income taxes 
Provision for income taxes 
Net loss 
Preferred stock beneficial conversion charge 
Undeclared cumulative preferred dividends 
Net loss attributable to common stockholders 
Net loss per share attributable to common stockholders – basic and diluted 
Weighted average shares outstanding – basic and diluted 

Years Ended March 31, 
2015  

2014  

3,935,320     $ 
2,766,391       
1,168,929       

6,409,381       
352,580       
6,761,961       
(5,593,032 )     

—      
(1,428,015 )     
(4,266 )     
—      
(7,025,313 )     
(1,600 )     
(7,026,913 )     
(4,864,292 )     
(305,328 )     
(12,196,533 )   $ 
(2.44 )   $ 
5,006,219       

2,659,943   
2,222,988   
436,955   

5,106,219   
409,111   
5,515,330   
(5,078,375 ) 

(13,713,767 ) 
(784,454 ) 
(8,078 ) 
20,848   
(19,563,826 ) 
(1,600 ) 
(19,565,426 ) 
—  
—  
(19,565,426 ) 
(4.81 ) 
4,070,876   

  $ 

  $ 
  $ 

See accompanying notes to consolidated financial statements.  

F- 4 

   
   
   
   
   
  
  
  
  
  
  
    
  
    
    
    
        
    
    
    
    
    
    
        
    
    
    
    
    
    
    
    
    
    
    
Cryoport, Inc. and Subsidiary  

Consolidated Statements of Stockholders’ (Deficit) Equity  

Class A 
Preferred Stock 

Class B 
Preferred Stock 

Common Stock 

   Shares 

     Amount 

     Shares 

     Amount 

     Shares 

     Amount 

     Additional 
    Paid–In Capital     

    Accumulated       Stockholders’    
     (Deficit) Equity   

Deficit 

Total 

Balance at March 31, 2013     
Net loss 
Stock-based compensation 
expense 
Estimated relative fair 

value of warrants issued 
in connection with 
convertible bridge notes 
payable 

Issuance of common stock 

upon exercise of 
options and warrants 
Issuance of common stock 
units upon conversion 
of convertible bridge 
notes and accrued 
interest 

Induced debt conversion 
expense 
Balance at March 31, 2014     
Net loss 
Stock-based compensation 
expense 
Issuance of Class A 

convertible preferred 
stock, net of offering 
costs of $577,600 
Issuance of Class A 

convertible preferred 
stock upon conversion 
of 5% bridge notes and 
accrued interest 
Issuance of Class B 

convertible preferred 
stock, net of offering 
costs of $249,000 

Issuance of common stock 

upon exercise of 
options and warrants 
Accretion of the fair value 
of the Class A and 
Class B convertible 
preferred stock 
beneficial conversion 
features and relative fair 
value of warrants 
Estimated relative fair 
value of beneficial 
conversion feature of 
5% bridge notes 

Issuance of restricted stock 

in connection with 
consulting agreement 

Estimated relative fair 

value of warrants issued 
in connection with 
related-party notes 
payable 

Estimated relative fair 

value of warrants issued 
in connection with 7% 
notes payable 

  —    $   
—      

—      

—      
—      

—      

—    $   
—      

—       3,146,719     $   
—      

—    

3,147     $   
—    

64,245,026     $   (66,311,448 )     $   

(2,063,275 )   

—    

(19,565,426 )      

( 19,565,426 ) 

—      

—      

—      

—      

678,119       

—       

678,119   

—      

—      

—      

—      

—      

—      

478,229       

—       

478,229   

—      

—      

—      

—      

131,943       

132       

326,758       

—       

326,890   

—      

—      
—      
—      

—      

—      

—      
—      
—      

—      

—      

—      
—      
—      

—      

—       1,719,668       

1,720       

4,125,481       

—       

4,127,201   

—      
—      
—       4,998,330       
—      
—      

—      
4,999       
—      

13,713,767       
83,567,380       
—      

—       
(85,876,874 )      
(7,026,913 )      

13,713,767   
(2,304,495 ) 
(7,026,913 ) 

—      

—      

—      

864,306       

—       

864,306   

291,142       

291       

—      

—      

—      

—      

2,915,774       

—       

2,916,065   

163,608       

164       

—      

—      

—      

—      

1,766,833       

—       

1,766,997   

—      

161,709       

162       

—      

—      

1,691,344       

—       

1,691,506   

—      

—      

—      

—      

23,913       

24       

92,585       

—       

92,609   

—      

—      

—      

—      

—      

—      

4,864,292       

(4,864,292 )      

—  

—      

—      

—      

—      

—      

—      

826,919       

—       

826,919   

—      

—      

—      

—      

3,334       

3       

17,397       

—       

17,400   

—      

—      

—      

—      

—      

—      

280,370       

—       

280,370   

—      

—      

—      

—      

—      

—      

458,937       

—       

458,937   

Balance at March 31, 2015     

454,750     $ 

455       

161,709     $ 

162        5,025,577     $ 

5,026     $ 

97,346,137     $  (97,768,079 )    $ 

(416,299 ) 

See accompanying notes to consolidated financial statements.  

F- 5 

     
   
   
   
   
  
  
  
    
    
  
    
  
    
  
    
  
     
  
  
  
    
    
  
    
    
    
    
    
    
    
    
    
    
    
        
    
    
    
    
    
    
  
    
        
        
        
        
        
        
        
         
    
Cryoport, Inc. and Subsidiary  

Consolidated Statements of Cash Flows  

Cash Flows From Operating Activities: 

Net loss 
Adjustments to reconcile net loss to net cash used in operating activities: 

Depreciation and amortization 
Amortization of debt discount and deferred financing costs 
Stock-based compensation expense 
Change in fair value of derivative instruments 
Loss on disposal of cryogenic shippers 
Provision for bad debt 
Debt conversion expense 
Changes in operating assets and liabilities: 

Accounts receivable, net 
Inventories 
Other assets 
Accounts payable and other accrued expenses 
Accrued compensation and related expenses 
Accrued interest 

Net cash used in operating activities 

Cash Flows From Investing Activities: 

Purchases of property and equipment 

Cash Flows From Financing Activities: 

Net cash used in investing activities 

Proceeds from the issuance of Class A and Class B convertible preferred stock, net of 

offering costs 

Proceeds from exercise of stock options and warrants 
Proceeds from the issuance of notes payable 
Proceeds from issuance of convertible debt 
Repayment of notes payable 
Repayment of convertible debt 
Repayment of offering and deferred financing costs 
Repayment of related-party notes payable 

Net cash provided by financing activities 

Net change in cash and cash equivalents 

Cash and cash equivalents — beginning of year 
Cash and cash equivalents — end of year 

Supplemental Disclosure of Cash Flow Information: 

Cash paid for interest 
Cash paid for income taxes 

Supplemental Disclosure of Non-Cash Investing and Financing Activities: 

Deferred financing costs in connection with convertible debt payable included in accounts 

payable 

Accretion of convertible preferred stock beneficial conversion feature and relative fair 

value of warrants issued in connection with the convertible preferred stock units to 
accumulated deficit 

Years Ended March 31, 
2014 
2015 

  $ 

(7,026,913 )   $ 

(19,565,426 ) 

197,938       
1,368,305       
881,706       
—      
16,423       
2,713       
—      

(76,587 )     
(39,977 )     
10,174       
209,138       
271,424       
57,954       
(4,127,702 )     

311,590   
678,915   
678,119   
(20,848 ) 
16,066   
24,876   
13,713,767   

(323,604 ) 
9,509   
(26,588 ) 
(221,929 ) 
236,856   
108,038   
(4,380,659 ) 

(70,130 )     
(70,130 )     

(138,886 ) 
(138,886 ) 

4,607,571       
92,609       
915,000       
—      
(173,623 )     
(50,000 )     
(30,120 )     
(128,000 )     
5,233,437       
1,035,605       
369,581       
1,405,186     $ 

753     $ 
1,600     $ 

—  
326,890   
—  
4,558,301   
—  
—  
(463,169 ) 
(96,000 ) 
4,326,022   
(193,523 ) 
563,104   
369,581   

—  
1,600   

—    $ 

30,120   

  $ 

  $ 
  $ 

  $ 

  $ 

4,864,292     $ 

—  

Estimated relative fair value of warrants issued in connection with convertible bridge notes 

payable 

  $ 

—    $ 

478,229   

Estimated relative fair value of warrants issued in connection with related-party convertible 

notes payable 

Estimated relative fair value of warrants issued in connection with notes payable 
Conversion of bridge notes payable and accrued interest into common stock units 
Conversion of convertible debentures payable and accrued interest into convertible 

preferred stock units 

  $ 
  $ 
  $ 

  $ 

280,370     $ 
458,937     $ 
—    $ 

—  
—  
4,127,201   

1,766,997     $ 

—  

See accompanying notes to consolidated financial statements.    

   
   
   
   
   
  
  
  
  
  
  
    
  
    
        
    
    
        
    
    
    
    
    
    
    
    
    
        
    
    
    
    
    
    
    
    
    
        
    
    
    
    
        
    
    
    
    
    
    
    
    
    
    
    
    
    
        
    
    
        
    
F- 6 

Cryoport, Inc. and Subsidiary  

Notes to Consolidated Financial Statements  

Note 1. Nature of the Business  

Cryoport Inc. (the “Company”, “Cryoport”, “we” or “our”) is a Nevada corporation originally incorporated under the name G.T.5-Limited 
(“GT5”) on May 25, 1990. In connection with a Share Exchange Agreement, on March 15, 2005 we changed our name to Cryoport, Inc. and 
acquired all of the issued and outstanding shares of common stock of Cryoport Systems, Inc., a California corporation, in exchange for 200,901 
shares of our common stock (which represented approximately 81% of the total issued and outstanding shares of common stock following the 
close  of  the  transaction).  Cryoport  Systems,  Inc.,  which  was  originally  formed  in  1999  as  a  California  limited  liability  company,  and 
subsequently reorganized into a California corporation on December 11, 2000, remains an operating company under Cryoport, Inc. We became 
“publicly held” by the reverse merger with GT5 described above. Over time the Company transitioned from being a development company to a 
fully operational public company in early 2011, providing global cryogenic logistics solutions to the biotechnology and life sciences industries.  

The Company became public by a reverse merger with a shell company in May 2005. Over time the Company has transitioned from being 
a development company to a fully operational public company, providing cold chain logistics solutions to the biotechnology and life sciences 
industries globally.  

Since fiscal year 2011, the Company has taken significant steps towards commercialization of the Cryoport Express ® logistics solutions in 
validating,  perfecting  and  expanding  its  features.  The  Company  has  now  managed  shipments  of  its  Cryoport  Express  ®  Shippers  through  its 
Cryoportal TM into and out of more than 80 countries, handling a vast array of different biological products and specimens.  

We  provide  cryogenic  logistics  solutions  to  the  life  sciences  industry  through  a  combination  of  purpose-built  proprietary  packaging, 
information technology and specialized cold chain logistics knowhow. We view our solutions as disruptive to the “older technologies” of dry ice 
and liquid nitrogen, in that our solutions are comprehensive and combine our competencies in configurations that are customized to our client’s 
requirements.  We  provide  comprehensive,  reliable,  economic  alternatives  to  all  existing  logistics  solutions  and  services  utilized  for  frozen 
shipping in the life sciences industry (e.g., personalized medicine, stem cells, cell lines, vaccines, diagnostic materials, semen, eggs, embryos, 
cord  blood,  bio-pharmaceuticals,  infectious  substances,  and  other  commodities  that  require  continuous  exposure  to  cryogenic  or  frozen 
temperatures). We provide the ability to monitor, record and archive crucial information for each shipment that can be used for scientific and 
regulatory purposes.  

Our Cryoport Express ® Solutions include a sophisticated cloud-based logistics operating platform, which is branded as the Cryoportal™. 
The Cryoportal™ supports the management of the entire shipment and logistics process through a single interface, including initial order input, 
document preparation, customs clearance, courier management, shipment tracking, issue resolution, and delivery. In addition, it provides unique 
and incisive information dashboards and validation documentation for every shipment. The Cryoportal™ records and retains a fully documented 
“chain-of-custody” and, at the client’s option, “chain-of-condition” for every shipment, helping ensure that quality, safety, efficacy, and stability 
of  shipped  commodities  are  maintained  throughout  the  process.  This  recorded  and  archived  information  allows  our  clients  to  meet  exacting 
requirements necessary for scientific work and for proof of regulatory compliance during the logistics phase.  

The  branded  packaging  for  our  Cryoport  Express  ®  Solutions  includes  our  liquid  nitrogen  dry  vapor  shippers,  the  Cryoport  Express  ® 
Shippers.  The  Cryoport  Express  ®  Shippers  are  cost-effective  and  reusable  cryogenic  transport  containers  (our  standard  shipper  is  a  patented 
vacuum  flask)  utilizing  an  innovative  application  of  “dry  vapor”  liquid  nitrogen  (“LN2”)  technology.  Cryoport  Express  ®  Shippers  are 
International Air Transport Association (“IATA”) certified and validated to maintain stable temperatures of minus 150° C and below for a 10-
day dynamic shipment period. The Company currently features three Cryoport Express ® Shippers: the Standard Dry Shipper (holding up to 75 
2.0 ml vials), the High Volume Dry Shipper (holding up to 500 2.0 ml vials) and the recently introduced Cryoport Express ® CXVC1 Shipper 
(holding up to 1,500 2.0 ml vials). In addition, we assist clients with internal secondary packaging as well (e.g., vials, canes, straws, plates, etc.)  

Our most used solution is the “turnkey” solution, which can be accessed directly through our cloud-based Cryoportal™ or by contacting 
Cryoport Client Care for order entry. Once an order is placed and cleared, we ship a fully charged Cryoport Express ® Shipper to the client who 
conveniently  loads  its  frozen  commodity  into  the  inner  chamber  of  the  Cryoport  Express  ®  Shipper  .   The  customer  then  closes  the  shipper 
package and reseals the shipping box displaying the next recipient’s address (“Flap A”) for pre-arranged carrier pick up.  Cryoport arranges for 
the pick-up of the parcel by a shipping service provider, which is designated by the client or chosen by Cryoport, for delivery to the client’s 
intended recipient.  The recipient simply opens the shipper package and removes the frozen commodity that  has been shipped.  The recipient 
then reseals the package, displaying the nearest Cryoport Operations Center address (“Flap B”), making it ready for pre-arranged carrier pick-up. 
The  When  the  Cryoport  Operations  Center  receives  the  Cryoport  Express  ®  Shipper,  it  is  cleaned,  put  through  quality  assurance  testing,  and 
returned to inventory for reuse.  

F- 7 

   
   
   
   
   
   
   
   
    
   
   
  
In late 2012, we shifted our focus to become a comprehensive cryogenic logistics solutions provider. Recognizing that clients in the life 
sciences industry have varying requirements, we unbundled our technologies, establishing customer facing solutions and taking a consultative 
approach to the market. Today, in addition to our standard “Turn-key Solution,” described above, we also provide the following customer facing, 
value-added solutions to address our various clients’ needs:  

  • 

  • 

  • 

  • 

  • 

  • 

“ Customer Staged Solution ,” designed for clients making 50 or more shipments per month. Under this solution, we supply an inventory 
of our Cryoport Express  ® Shippers to our customer, in an uncharged state, enabling our customer (after training/certification) to charge 
them with liquid nitrogen and use our Cryoportal™ to enter orders with shipping and delivery service providers for the transportation of the 
package.  Once  the  order  is  released,  our  customer  services  professionals  monitor  the  shipment  and  the  return  of  the  shipper  to  us  for 
cleaning, quality assurance testing and reuse. 

“ Customer Managed Solution ,” a limited customer implemented solution whereby we supply our Cryoport Express ® Shippers to clients 
in  a  fully  charged  state,  but  leaving  it  to  the  client  to  manage  the  shipping,  including  the  selection  of  the  shipping  and  delivery  service 
provider and the return of the shipper to us. . 

“  powered by  Cryoport  SM ,”  available to  providers of shipping  and  delivery  services  who  seek  to offer  a “branded” cryogenic  logistics 
solution as part of their service offerings, with “ powered by Cryoport SM ” appearing prominently on the offering software interface and 
packaging. This solution can also be private labeled upon meeting certain requirements, such as minimum required shipping volumes. 

“ Integrated Solution, ” which is our outsource solution. It is our most comprehensive solution and involves our management of the entire 
cryogenic  logistics  process  for  our  client,  including  Cryoport  employees  at  the  client’s  site  to  manage  the  client’s  cryogenic  logistics 
function in total. 

“ Regenerative Medicine Point-of-Care Repository Solution, ” designed for allogeneic therapies. In this model we supply our Cryoport 
Express ® Shipper to ship and store cryogenically preserved life science products for up to 6 days (or longer periods with supplementary 
shippers) at a point-of-care site, with the Cryoport Express ® Shipper serving as a temporary freezer/repository enabling the efficient and 
effective  distribution  of  temperature  sensitive  allogeneic  cell-based  therapies  without  the  expense,  inconvenience,  and  potential  costly 
failure  of an on-sight, cryopreservation  device. Our customer  service professionals  monitor each  shipment throughout the predetermined 
process including the return of the shipper to us. When the Cryoport Operations Center receives the Cryoport Express ® Shipper package it 
is cleaned, put through quality assurance testing, and returned to inventory for reuse. 

“  Personalized  Medicine  and  Cell-based  Immunotherapy  Solution,  ”  designed  for  autologous  therapies.  In  this  model  our  Cryoport 
Express ® Shipper serves as an enabling technology for the safe transportation of manufactured autologous cellular-based immunotherapy 
market by providing a comprehensive logistics solution for the verified chain of custody and condition transport from, (a) the collection of 
the patient’s cells in a hospital setting, to (b) a central processing facility where they are manufactured into a personalized medicine, to (c) 
the safe, cryogenically preserved return of these irreplaceable cells to a point-of-care treatment facility.  If required, the Cryoport Express ® 
Shipper can then serve as a temporary freezer/repository to allow the efficient distribution of this personalized medicine to the patient when 
and  where  the  medical  provider  needs  it  most  without  the  expense,  inconvenience,  and  potential  costly  failure  of  an  on-sight, 
cryopreservation device. Our customer services professionals monitor each shipment throughout the predetermined process, including the 
return  of  the  shipper  to  us.  When  the  Cryoport  Operations  Center  receives  the  Cryoport  Express  ®  Shipper  package  it  is  cleaned,  put 
through quality assurance testing, and returned to inventory for reuse. 

Strategic Logistics Alliances  

We have sought to establish strategic alliances as a method of marketing our solutions providing minus 150° C shipping conditions to the 
life  sciences  industry.  We  have  focused  our  efforts  on  leading  companies  in  the  logistics  services  industry  as  well  as  participants  in  the  life 
sciences industry. In connection with our alliances with providers of shipping services, we refer to their offerings as “ powered by Cryoport SM ”
to reflect our solutions being integrated into our alliance partner’s services.  

Cryoport  now  serves  and  supports  the  three  largest  integrators  in  the  world,  responsible  for  over 85%  of worldwide  airfreight,  with  its 
advanced cryogenic logistics solutions for life sciences. We operate  with each independently and confidentially in support  of  their  respective 
market  and  sales  strategies.  We  maintain  our  independent  partnerships  with  strict  confidentiality  guidelines  within  the  Company.  These 
agreements represent a significant validation of our solutions and the way we conduct our business.  

F- 8 

   
   
   
   
     
   
    
   
   
   
   
  
FedEx.  In  January  2013,  we  entered  into  a  master  agreement  with  Federal  Express  Corporation  (“FedEx”)  (the  “FedEx  Agreement”) 
renewing these services and providing FedEx with a non-exclusive license and right to use a customized version of our Cryoportal  TM for the 
management of shipments made by FedEx customers. The FedEx Agreement became effective on January 1, 2013 and, unless sooner terminated 
as  provided  in  the  FedEx  Agreement,  expires  on  December  31,  2015.  FedEx  has  the  right  to  terminate  this  agreement  at  any  time  for 
convenience upon 180 days’ notice.  

Under  our  FedEx  Agreement,  we  provide  frozen  shipping  logistics  services  through  the  combination  of  our  purpose-built  proprietary 
technologies  and  turnkey  management  processes.  FedEx  markets  and  sells  Cryoport’s  services  for  frozen  temperature-controlled  cold  chain 
transportation  as  its  FedEx  ®  Deep  Frozen  Shipping  Solution  on  a  non-exclusive  basis  and  at  its  sole  expense.  During  fiscal  year  2013,  the 
Company  worked  closely  with  FedEx  to  further  align  its  sales  efforts  and  accelerate  penetration  within  FedEx’s  life  sciences  customer  base 
through improved processes, sales incentives, joint customer calls and more frequent communication at the sales and executive level. In addition, 
FedEx has developed a FedEx branded version of the Cryoportal TM software platform, which is “ powered by Cryoport SM ” for use by FedEx 
and its customers giving them access to the full capabilities of our cloud-based logistics management software platform.  

DHL. In June 2014, we entered into a master agreement with LifeConEx, a part of DHL Global Forwarding (“DHL”). This relationship 
with DHL is a further implementation of the Company’s expansion of distribution partnerships under the “ powered by Cryoport  SM ” model 
described above, allowing us to expand our sales and marketing reach through our partners and build awareness of the benefits of our validated 
cryogenic  solution  offerings.  DHL  can  now  enhance  and  supplement  its  cold  chain  logistics  offerings  to  its  life  sciences  and  healthcare 
customers with Cryoport’s validated cryogenic solutions. DHL added 15 additional certified Life Sciences stations in the second quarter of 2014 
bringing the Thermonet network to 60 stations in operation. Over the course of rolling out our new relationship, this expanded network will offer 
Cryoport’s cryogenic solutions under the DHL brands as “ powered by Cryoport SM ”. In addition, DHL’s customers will be able to have direct 
access to our cloud-based order entry and tracking portal to order Cryoport Express ® Solutions and receive preferred DHL shipping rates and 
discounts. Our proprietary logistics management operating platform, the Cryoportal TM , is integrated with DHL’s tracking and billing systems to 
provide  DHL  life  sciences  and  healthcare  customers  with  a  seamless  way  of  accessing  critical  information  regarding  shipments  of  biological 
material worldwide.  

UPS. In October 2014, we added United Parcel Services, Inc. (“UPS”) as our third major distributor by entering into an agreement with 
UPS Oasis Supply Corporation, a part of UPS, whereby UPS will offer our validated and comprehensive cryogenic solutions to its life sciences 
and healthcare customers on a global basis. This relationship with UPS is a further implementation of the Company’s expansion of distributors 
under the “ powered by Cryoport SM ” model described above, allowing us to further expand our sales and marketing reach through our partners 
and build awareness of the benefits of our validated cryogenic solution offerings through UPS.  

Over the course of rolling out our new relationship with UPS, UPS customers will have direct access to our cloud-based order entry and 
tracking portal to order Cryoport Express ® Solutions and gain access to UPS’s broad array of domestic and international shipping and logistics 
solutions at competitive prices. Our proprietary logistics management operating platform, the Cryoportal TM , is integrated with UPS’s tracking 
and  billing  systems  to  provide  UPS  life  sciences  and  healthcare  customers  with  a  seamless  way  of  accessing  critical  information  regarding 
shipments of biological material worldwide.  

These agreements the three largest integrators in the world represent a significant validation of our solutions and the way we conduct our 

business.  

Life Sciences Agreements  

Zoetis. In December 2012, we  signed an agreement with Pfizer  Inc. relating to  Zoetis Inc. (formerly the animal health  business unit of 
Pfizer  Inc.)  pursuant  to  which  we  were  engaged  to  manage  frozen  shipments  of  a  key  poultry  vaccine.  Under  this  arrangement,  Cryoport 
provides on-site logistics personnel and its logistics management operating platform, the Cryoportal  TM to manage shipments from the Zoetis 
manufacturing  site  in  the  United  States  to  domestic  customers  as  well  as  various  international  distribution  centers.  As  part  of  our  logistics 
management services, Cryoport is constantly analyzing logistics data and processes to further introduce economies and reliability throughout the 
network,  ensuring  products  arrive  at  their  destinations  in  specified  conditions,  on-time  and  with  the  optimum  utilization  of  resources.  The 
Company  manages  Zoetis’  total  fleet  of  dewar  flask  shippers  used  for  this  purpose,  including  liquid  nitrogen  shippers.  In  July  2013  the 
agreement  was  amended  to expand  Cryoport’s scope  to  manage  all logistics  of  Zoetis’ key  frozen poultry  vaccine  to  all  Zoetis’ international 
distribution centers as well as all domestic shipments. In October 2013, the agreement was further amended to further expand Cryoport’s role to 
include the logistics management for a second poultry vaccine.  

F- 9 

    
   
   
   
   
   
   
   
   
  
Liventa Biosciences. In February 2014, we entered into a services agreement with Liventa Bioscience, Inc. (“Liventa”), a privately-held, 
commercial stage biotechnology company focused on cell-based, advanced biologics in the orthopedic industry. Under this agreement, Liventa 
will  use  Cryoport’s  Regenerative  Medicine  Point-of-Care  Repository  Solution  for  the  logistics  of  its  cell-based  therapies  requiring  cryogenic 
temperatures and also provide Cryoport Express ® Solutions to other biologics suppliers within the orthopedic arena. The agreement combines 
Cryoport’s proprietary, purpose-built cold chain logistics solutions for cell-based and advanced biologic tissue forms with Liventa’s distribution 
capability  to  orthopedic  care  providers.  The  implementation  of  Cryoport’s  Regenerative  Medicine  Point-of-Care  Repository  Solution  will 
eliminate  the  risks  of  degradation  and  also  eliminate  the  need  for  expensive  onsite  cryogenic  freezers  for  storage  of  cell-based  orthopedic 
therapies. This will enable Liventa to confidently serve orthopedic practices, surgical centers, pain clinics, hospitals and, eventually, pharmacies 
and specialty care providers. The agreement has an initial three-year term and may be renewed for consecutive three-year terms, unless earlier 
terminated  by  either  party.  Liventa  also  agreed  to  certain  performance  criteria  and  the  issuance  of  150,000  shares  of  its  common  stock  to 
Cryoport in exchange for the exclusive right to offer, market and promote Cryoport Express ® Solutions for cellular-based therapies requiring 
cryogenic temperatures for use in the orthopedic arena in the United States.  

In summary, we serve the life sciences industry with cryogenic logistics solutions that are advanced, comprehensive, reliable, validated, 
and efficient. Our clients include those companies and institutions that have logistics requirements for personalized medicine, immunotherapies, 
stem cells, cell lines, tissue, vaccines, in-vitro fertilization, cord blood, and other temperature sensitive commodities of life sciences.  

Going Concern  

The consolidated financial statements have been prepared using the accrual method of accounting in accordance with accounting principles 
generally accepted in the United States of America (“U.S. GAAP”) and have been prepared on a going concern basis, which contemplates the 
realization of assets and the settlement of liabilities in the normal course of business. We have sustained operating losses since our inception and 
have used substantial amounts of working capital in our operations. At March 31, 2015, we had an accumulated deficit of $97.8 million. During 
the year ended March 31, 2015, we used cash in operations of $4.1 million and had a net loss of $7.0 million.  

We expect to continue to incur substantial additional operating losses from costs related to the commercialization of our Cryoport Express 
® Solutions and do not expect that revenues from operations will be sufficient to satisfy our funding requirements in the near term. We believe 
that our cash resources at March 31, 2015, additional funds raised subsequent to March 31, 2015 through the Class B convertible preferred stock 
(see Note 15), together with the revenues generated from our services will be sufficient to sustain our planned operations into the third quarter of 
fiscal  year  2016;  however,  we  must  obtain  additional  capital  to  fund  operations  thereafter  and  for  the  achievement  of  sustained  profitable 
operations.  These  factors  raise  substantial  doubt  about  our  ability  to  continue  as  a  going  concern.  We  are  currently  working  on  funding 
alternatives in order to secure sufficient operating capital to allow us to continue to operate as a going concern.  

Future  capital  requirements  will  depend  upon  many  factors,  including  the  success  of  our  commercialization  efforts  and  the  level  of 
customer adoption of our Cryoport Express ® Solutions as well as our ability to establish additional collaborative arrangements. We cannot make 
any assurances that the sales ramp will lead to achievement of sustained profitable operations or that any additional financing will be completed 
on a timely basis and on acceptable terms or at all. Management’s inability to successfully achieve significant revenue increases or implement 
cost reduction strategies or to complete any other financing will adversely impact our  ability to continue as a going concern. To address this 
issue, the Company is seeking additional capitalization to properly fund our efforts to become a self-sustaining financially viable entity.  

Note 2. Summary of Significant Accounting Policies  

Basis of Presentation  

The accompanying consolidated financial statements have been prepared in accordance with U.S. GAAP.  

On May 12, 2015, our Board of Directors approved an amendment to our certificate of incorporation to effect a reverse stock split by a 
ratio  of  1-for-12,  with  no  reduction  in  the  number  of  shares  of  common  stock  that  were  previously  authorized  in  our  certificate  of 
incorporation.  The reverse stock split is effective on May 19, 2015.  Unless otherwise noted, all share and per share data in this annual report 
give effect to the 1-for-12 reverse stock split of our common stock. Financial information updated by this capital change includes earnings per 
common  share,  dividends  per  common  share,  stock  price  per  common  share,  weighted  average  common  shares,  outstanding  common  shares, 
treasury shares, common stock, additional paid-in capital, and share-based compensation.    

F- 10 

   
   
   
   
   
   
   
   
   
   
   
  
Principles of Consolidation  

The consolidated financial statements include the accounts of Cryoport, Inc. and its wholly owned subsidiary, Cryoport Systems, Inc. All 

intercompany accounts and transactions have been eliminated.  

Use of Estimates  

The  preparation  of  financial  statements  in  conformity  with  U.S.  GAAP  requires  management  to  make  estimates  and  assumptions  that 
affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and 
the reported amounts of revenues and expenses during the reporting periods. Actual results could differ from estimated amounts. The Company’s 
significant  estimates  include  allowances  for  doubtful  accounts,  recoverability  of  long-lived  assets,  allowance  for  inventory  obsolescence, 
deferred taxes and their accompanying valuations, and valuation of equity instruments and conversion features.  

Fair Value of Financial Instruments  

The Company’s financial instruments consist of cash and cash equivalents, accounts receivable, related-party notes payable, convertible 
debentures payable, notes payable, accounts payable and accrued expenses. The carrying value for all such instruments approximates fair value 
at March 31, 2015 and 2014 due to their short-term nature. The difference between the fair value and recorded values of the related-party notes 
payable is not significant.  

Cash and Cash Equivalents  

The Company considers highly liquid investments with original maturities of 90 days or less to be cash equivalents.  

Concentrations of Credit Risk  

The  Company  maintains  its  cash  accounts  in  financial  institutions.  Accounts  at  these  institutions  are  insured  by  the  Federal  Deposit 
Insurance  Corporation  (“FDIC”)  with  basic  deposit  insurance  coverage  limits  up  to  $250,000  per  owner.  At  March  31,  2015  and  2014,  the 
Company had cash balances of approximately $1.3 million and $159,000, respectively, which exceeded the FDIC insurance limit. The Company 
performs ongoing evaluations of these institutions to limit its concentration risk exposure.  

Customers  

The Company grants credit to customers within the U.S. and to a limited number of international customers and does not require collateral. 
Revenues from international customers are generally secured by advance payments except for a limited number of established foreign customers. 
The Company  generally requires advance  or  credit  card  payments  for initial revenues  from new  customers.  The  Company’s  ability  to collect 
receivables  is  affected  by  economic  fluctuations  in  the  geographic  areas  and  industries  served  by  the  Company.  Reserves  for  uncollectible 
amounts  are  provided  based  on  past  experience  and  a  specific  analysis  of  the  accounts,  which  management  believes  is  sufficient.  Accounts 
receivable at March 31, 2015 and 2014 are net of reserves for doubtful accounts of $12,200 and $24,600, respectively. Although the Company 
expects to collect amounts due, actual collections may differ from  the estimated amounts. The Company maintains reserves for bad debt and 
such losses, in the aggregate, historically have not exceeded our estimates.  

The majority of the Company’s customers are in the biotechnology, pharmaceutical and life science industries. Consequently, there is a 
concentration of accounts receivable within these industries, which is subject to normal credit risk. At March 31, 2015 and 2014, respectively, 
there was one customer that accounted for 14.6% and 30.6% of net accounts receivable. No other single customer owed us more than 10% of net 
accounts receivable at March 31, 2015 and 2014.  

The Company has revenue from foreign customers primarily in Europe, Japan, Canada, India and Australia. During fiscal years 2015 and 
2014,  the  Company  had  revenues  from  foreign  customers  of  approximately  $617,200  and  $434,000,  respectively,  which  constituted 
approximately 15.7% and 16.3% of total revenues, respectively. For the fiscal year ended March 31, 2015 and 2014, there was one customer that 
accounted for 22.7% and 30.8% of total revenues. No other single customer generated over 10% of total revenues during 2015 and 2014.  

F- 11 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
Inventories  

The Company’s inventories consist of accessories that are sold and shipped to customers along with pay-per-use containers that are not 
returned to the Company with the containers at the culmination of the customer’s shipping cycle. Inventories are stated at the lower of cost or 
current  estimated  market  value.  Cost  is  determined  using  the  standard  cost  method  which  approximates  the  first-in,  first-to-expire  method. 
Inventories  are  reviewed  periodically  for  slow-moving  or  obsolete  status.  The  Company  writes  down  the  carrying  value  of  its  inventories  to 
reflect situations in which the cost of inventories is not expected to be recovered. Once established, write-downs of inventories are considered 
permanent  adjustments  to  the  cost  basis  of  the  obsolete  or  excess  inventories.  Raw  materials  and  finished  goods  include  material  costs  less 
reserves  for  obsolete  or  excess  inventories.  The  Company  evaluates  the  current  level  of  inventories  considering  historical  trends  and  other 
factors, and based on the evaluation, records adjustments to reflect inventories at its net realizable value. These adjustments are estimates, which 
could vary significantly from actual results if future economic conditions, customer demand, competition or other relevant factors differ from 
expectations. These estimates require us to make assessments about future demand for the Company’s products in order to categorize the status 
of such inventories items as slow-moving, obsolete or in excess-of-need. These estimates are subject to the ongoing accuracy of the Company’s 
forecasts of market conditions, industry trends, competition and other factors.  

Property and Equipment  

The Company provides shipping containers to its customers and charges a fee in exchange for the use of the container. The Company’s 
arrangements  are  similar  to  the  accounting  standard  for  leases  since  they  convey  the  right  to  use  the  container  over  a  period  of  time.  The 
Company retains the title to the containers and provides its customers the use of the container for a specific shipping cycle. At the culmination of 
the customer’s shipping cycle, the container is returned to the Company. As a result, the Company classifies the containers as fixed assets for the 
per-use container program.  

Property and equipment are recorded at cost. Cryogenic shippers, which comprise of 90% and 89% of the Company’s net property and 
equipment balance at March 31, 2015 and 2014, respectively, are depreciated using the straight-line method over their estimated useful lives of 
three years. Equipment and furniture are depreciated using the straight-line method over their estimated useful lives (generally three to seven 
years)  and  leasehold  improvements  are  amortized  using  the  straight-line  method  over  the  estimated  useful  life  of  the  asset  or  the  lease  term, 
whichever  is  shorter.  Equipment  acquired  under  capital  leases  is  amortized  over  the  estimated  useful  life  of  the  assets  or  term  of  the  lease, 
whichever is shorter and included in depreciation and amortization expense.  

Betterments, renewals and extraordinary repairs that extend the lives of the assets are capitalized; other repairs and maintenance charges 
are  expensed  as  incurred.  The  cost  and  related  accumulated  depreciation  and  amortization  applicable  to  assets  retired  are  removed  from  the 
accounts, and the gain or loss on disposition is recognized in current operations.  

Intangible Assets  

Intangible assets are comprised of patents and trademarks and software development costs. The Company capitalizes costs of obtaining 
patents  and  trademarks,  which  are  amortized,  using  the  straight-line  method  over  their  estimated  useful  life  of  five  years.  The  Company 
capitalizes  certain  costs  related  to  software  developed  for  internal  use.  Software  development  costs  incurred  during  the  preliminary  or 
maintenance project stages are expensed as incurred, while costs incurred during the application development stage are capitalized and amortized 
using the straight-line method over the estimated useful life of the software, which is five years. Capitalized costs include purchased materials 
and costs of services including the valuation of warrants issued to consultants.  

Long-lived Assets  

If indicators of impairment exist, we assess the recoverability of the affected long-lived assets by determining whether the carrying value 
of such assets can be recovered through undiscounted future operating cash flows. If impairment is indicated, we measure the amount of such 
impairment by comparing the fair value to the carrying value. We believe the future cash flows to be received from the long-lived assets will 
exceed the assets’ carrying value, and accordingly, we have not recognized any impairment losses through March 31, 2015.  

Deferred Financing Costs  

Deferred  financing  costs  represent  costs  incurred  in  connection  with  the  issuance  of  the  convertible  notes  payable  and  private  equity 
financing.  Deferred  financing  costs  related  to  the  issuance  of  debt  are  being  amortized  over  the  term  of  the  financing  instrument  using  the 
effective interest method while deferred financing costs from equity financings are netted against the gross proceeds received from the equity 
financings.  

Conversion Features  

If  a  conversion  feature  of  convertible  debt  is  not  accounted  for  as  a  derivative  instrument  and  provides  for  a  rate  of  conversion  that  is 
below  market  value,  this  feature  is  characterized  as  a  beneficial  conversion  feature  (“BCF”).  A  BCF  is  recorded  by  the  Company  as  a  debt 
discount. The convertible debt is recorded net of the discount related to the BCF. The Company amortizes the discount to interest expense over 
the life of the debt using the effective interest rate method.  

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
F- 12 

Preferred stock is convertible to common stock at a rate of conversion that is below market value, therefore, this feature is characterized as 
a BCF. The Company records this BCF as a discount to the preferred stock and accretes the discount to retained earnings as a deemed dividend 
upon issuance of the preferred stock.     

Income Taxes  

The  Company  accounts  for  income  taxes  under  the  provision  of  the  Financial  Accounting  Standards  Board  (“FASB”)  Accounting 
Standards Codification  (“ASC”)  740,  Income Taxes , or  ASC 740. As of  March 31,  2015  and 2014, there  were no unrecognized  tax  benefits 
included in the accompanying consolidated balance sheets that would, if recognized, affect the effective tax rate.  

Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those 
temporary  differences  are  expected  to  be  recovered  or  settled.  The  effect  on  deferred  tax  assets  and  liabilities  of  a  change  in  tax  rates  is 
recognized in income in the period that includes the enactment date. A valuation allowance is provided for certain deferred tax assets if it is more 
likely than not that the Company will not realize tax assets through future operations. Based on the weight of available evidence, the Company’s 
management  has  determined  that  it  is  more  likely  than  not  that  the  net  deferred  tax  assets  will  not  be  realized.  Therefore,  the  Company  has 
recorded a full valuation allowance against the net deferred tax assets. The Company’s income tax provision consists of state minimum taxes.  

The Company’s policy is to recognize interest and/or penalties related to income tax matters in income tax expense. The Company had no 
accrual  for  interest  or  penalties  on  its  consolidated  balance  sheets  at  March  31,  2015  and  2014,  respectively  and  has  not  recognized  interest 
and/or penalties in the consolidated statements of operations for the years ended March 31, 2015 and 2014. The Company is subject to taxation 
in the U.S. and various state jurisdictions. As of March 31, 2015, the Company is no longer subject to U.S. federal examinations for years before 
2011  and  for  California  franchise  and  income  tax  examinations  for  years  before  2010.  However,  to  the  extent  allowed  by  law,  the  taxing 
authorities may have the right to examine prior periods where net operating losses were generated and carried forward, and make adjustments up 
to  the  amount  of  the  net  operating  loss  carry  forward  amount.  The  Company  is  not  currently  under  examination  by  U.S.  federal  or  state 
jurisdictions.  

Revenue Recognition  

The Company provides shipping containers to its customers and charges a fee in exchange for the use of the container. The Company’s 
arrangements  are  similar  to  the  accounting  standard  for  leases  since  they  convey  the  right  to  use  the  containers  over  a  period  of  time.  The 
Company retains title to the containers and provides its customers the use of the container for a specified shipping cycle. At the culmination of 
the customer’s shipping cycle, the container is returned to the Company.  

The  Company  recognizes  revenue  for  the  use  of  the  shipper  at  the  time  of  the  delivery  of  the  shipper  to  the  end  user  of  the  enclosed 

materials, and at the time that collectability is reasonably certain. Revenue is based on gross amounts, net of discounts and allowances.  

The Company also provides logistics support and management to some customers, which may include onsite logistics personnel. Revenue 

is recognized for these services as services are rendered and at the time that collectability is reasonably certain.  

Accounting for Shipping and Handling Revenue, Fees and Costs  

The Company classifies amounts billed for shipping and handling as revenue. Shipping and handling fees and costs are included in cost of 

revenues in the accompanying consolidated statements of operations.  

Research and Development Expenses  

Expenditures relating to research and development are expensed in the period incurred.  

Stock-based Compensation  

The  Company  accounts  for  stock-based  payments  to  employees  and  directors  in  accordance  with  stock-based  payment  accounting 
guidance which requires all stock-based payments to employees and directors, including grants of employee stock options and warrants, to be 
recognized based upon their estimated fair values. The fair value of stock-based awards is estimated at grant date using the Black-Scholes option 
pricing  method  (“Black-Scholes”)  and  the  portion  that  is  ultimately  expected  to  vest  is  recognized  as  compensation  cost  over  the  requisite 
service period.  

F- 13 

   
   
   
   
   
    
   
   
   
   
   
   
   
   
   
   
  
Since  stock-based  compensation  is  recognized  only  for  those  awards  that  are  ultimately  expected  to  vest,  the  Company  has  applied  an 
estimated forfeiture rate to unvested awards for the purpose of calculating compensation cost. These estimates will be revised, if necessary, in 
future periods if actual forfeitures differ from estimates. Changes in forfeiture estimates impact compensation cost in the period in which the 
change in estimate occurs. The estimated forfeiture rates at March 31, 2015 and 2014 was zero as the Company has not had a significant history 
of forfeitures and does not expect significant forfeitures in the future.  

Cash flows from the tax benefits resulting from tax deductions in excess of the compensation cost recognized for those options or warrants 
are classified as financing cash flows. Due to the Company’s loss position, there were no such tax benefits during years ended March 31, 2015 
and 2014.  

The Company uses Black-Scholes to estimate the fair value of stock-based awards. The determination of fair value using Black-Scholes is 
affected by the Company’s stock price as well as assumptions regarding a number of complex and subjective variables, including expected stock 
price volatility, risk-free interest rate, expected dividends and projected employee stock option exercise behaviors.  

The Company’s stock-based compensation plans are discussed further in Note 12.  

Equity Instruments Issued to Non-Employees for Acquiring Goods or Services  

Issuances of the Company’s common stock for acquiring goods or services are measured at the estimated fair value of the consideration 
received  or  the  estimated  fair  value  of  the  equity  instruments  issued,  whichever  is  more  reliably  measurable.  The  measurement  date  for  the 
estimated fair value of the equity instruments issued to consultants or vendors is determined at the earlier of (i) the date at which a commitment 
for performance to earn the equity instruments is reached (a “performance commitment” which would include a penalty considered to be of a 
magnitude that is a sufficiently large disincentive for nonperformance) or (ii) the date at which performance is complete. When it is appropriate 
for  the  Company  to  recognize  the  cost  of  a  transaction  during  financial  reporting  periods  prior  to  the  measurement  date,  for  purposes  of 
recognition of  costs  during  those  periods, the equity instrument  is  measured at  the then-current estimated fair values at  each  of those  interim 
financial reporting dates.  

Basic and Diluted Net Income (Loss) Per Share  

We calculate basic and diluted net income (loss) per share attributable to common stockholders using the weighted average number of 
common  shares  outstanding  during  the  periods  presented,  and  adjust  the  amount  of  net  income  (loss)  used  in  this  calculation  for  cumulative 
preferred stock dividends, (if any), whether they are earned or not during the period. In periods of a net loss position, basic and diluted weighted 
average  shares  are  the  same.  For  the  diluted  earnings  per  share  calculation,  we  adjust  the  weighted  average  number  of  common  shares 
outstanding to include dilutive stock options, warrants and shares associated with the conversion of convertible debt and convertible preferred 
stock outstanding during the periods. For the year ended March 31, 2015, the Company had cumulative, undeclared dividends that have not been 
accrued  related  to  its  preferred  stock  of  $305,328,  which  were  added  to  the  net  loss  on  the  consolidated  statement  of  operations  in  order  to 
calculate net loss per common share attributable to common stockholders.  

The following shows the amounts used in computing net loss per share for each of the two years in the period ended March 31, 2015:  

Net loss 
Less: 

Preferred stock beneficial conversion charge 
Undeclared cumulative preferred dividends 

Net loss attributable to common stockholders 
Weighted average shares issued and outstanding 
Basic and diluted net loss per share attributable to commons stockholders 

Years Ended March 31, 
2015  
(7,026,913 )   $ 

2014  
(19,565,426 ) 

(4,864,292 )     
(305,328 )     
(12,196,533 )   $ 
5,006,219       
(2.44 )   $ 

—  
—  
(19,565,426 ) 
4,070,876   
(4.81 ) 

  $ 

  $ 

  $ 

The following table sets forth the number of shares excluded from the computation of diluted earnings per share, as their inclusion would 

have been anti-dilutive:  

F- 14 

    
   
   
   
   
   
     
   
   
   
   
   
  
  
  
  
  
  
    
  
    
        
    
    
    
    
Class A convertible preferred stock 
Class B convertible preferred stock 
Stock options 
Warrants 

Segment Reporting  

We currently operate in one reportable segment.  

Fair Value Measurements  

Years Ended March 31, 
2014  
2015  
1,136,875       
404,273       
419,785       
436,779       
2,397,712        

—  
—  
288,193   
268,478   
556,671   

We measure fair value based on the prices that would be received to sell an asset or paid to transfer a liability in an orderly transaction 
between market participants at the measurement date. Fair value measurements are based on a three-tier hierarchy that prioritizes the inputs used 
to measure fair value. These tiers include the following:  

Level 1:  Quoted prices (unadjusted) in active markets for identical assets or liabilities that are accessible at the measurement date. The fair 

value hierarchy gives the highest priority to Level 1 inputs.  

Level 2:  Observable prices that are based on inputs not quoted on active markets, but corroborated by market data. These inputs include 
quoted prices for similar assets or liabilities; quoted market prices in markets that are not active; or other inputs that are observable or can be 
corroborated by observable market data for substantially the full term of the assets or liabilities. Currently we do not have any items classified as 
Level 2.  

Level 3:   Unobservable  inputs  are  used  when  little  or  no  market  data  is  available.  The  fair  value  hierarchy  gives  the  lowest  priority  to 

Level 3 inputs.  

 In  determining  fair  value,  we  utilize  valuation  techniques  that  maximize  the  use  of  observable  inputs  and  minimize  the  use  of 

unobservable inputs to the extent possible, as well as consider counterparty credit risk in the assessment of fair value.  

We have no assets or liabilities that are required to be measured at fair value on a recurring basis as of March 31, 2015 and 2014.  

Foreign Currency Transactions  

We record foreign currency transactions at the exchange rate prevailing at the date of the transaction with resultant gains and losses being 

included in results of operations. Foreign currency transaction gains and losses have not been significant for any of the periods presented.  

Recent Accounting Pronouncements  

In August 2014, the FASB issued ASU 2014-15, “Presentation of Financial Statements-Going Concern”. Currently, there is no guidance 
in U.S. GAAP about management’s responsibility to evaluate whether there is substantial doubt about an entity’s ability to continue as a going 
concern  or  to  provide  related  footnote  disclosures.  The  amendments  require  management  to  assess  an  entity’s  ability  to  continue  as  a  going 
concern by incorporating and expanding upon certain principles that are currently in U.S. auditing standards. Specifically, the amendments (1) 
provide  a  definition  of  the  term  substantial  doubt,  (2)  require  an  evaluation  every  reporting  period  including  interim  periods,  (3)  provide 
principles for considering the mitigating effect of management’s plans, (4) require certain disclosures when substantial doubt is alleviated as a 
result of consideration of management’s plans, (5) require an express statement and other disclosures when substantial doubt is not alleviated, 
and  (6)  require  an  assessment  for  a  period  of  one  year  after  the  date  that  the  financial  statements  are  issued  (or  available  to  be  issued).  The 
amendments  in  this  ASU  are  effective  for  the  reporting  periods  beginning  after  December  15,  2016  and  early  application  is  permitted. 
Management is currently assessing the impact the adoption of ASU 2014-15 will have on our consolidated financial statements.  

F- 15 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
    
  
    
    
    
    
  
     
In  May  2014,  the  FASB  issued  ASU  No.  2014-09,  “Revenue  from  Contracts  with  Customers”.  ASU  2014-09  supersedes  the  revenue 
recognition requirements in FASB Topic 605, "Revenue Recognition". The ASU implements a five-step process for customer contract revenue 
recognition that focuses on transfer of control, as opposed to transfer of risk and rewards. The amendment also requires enhanced disclosures 
regarding the nature, amount, timing and uncertainty of revenues and cash flows from contracts with customers. Other major provisions include 
the capitalization and amortization of certain contract costs, ensuring the time value of money is considered in the transaction price, and allowing 
estimates of variable consideration to be recognized before contingencies are resolved in certain circumstances. The amendments in this ASU are 
effective  for  interim  and  annual  periods  beginning  after  December  15,  2016  and  early  adoption  is  not  permitted.  In  April  2015,  the  FASB 
proposed a one year deferral  of the  effective  date  for public entities and others, related to this ASU. The comment  deadline for the one year 
deferral period is May 29, 2015. Entities can transition to the standard either retrospectively or as a cumulative-effect adjustment as of the date of 
adoption. Management has not selected a transition method and is currently assessing the impact the adoption of ASU 2014-09 will have on our 
consolidated financial statements  

Note 3. Inventories  

Inventories consist of the following:  

Raw materials 
Finished goods 

Note 4. Property and Equipment  

Property and equipment consist of the following:    

Cryogenic shippers 
Furniture and fixtures 
Machinery and equipment 
Leasehold improvements 

Less accumulated depreciation and amortization 

March 31,  

2015  

2014  

  $ 

  $ 

41,725     $ 
27,955       
69,680     $ 

18,283   
11,420   
29,703   

March  31,  

2015  
1,034,554     $ 
30,746       
350,520       
23,652       
1,439,472       
(1,131,546 )     
307,926     $ 

2014  
1,037,286   
30,746   
386,731   
30,913   
1,485,676   
(1,076,784 ) 
408,892   

  $ 

  $ 

Total depreciation and amortization expense related to property and equipment amounted to $154,700 and $219,400 for the years ended 

March 31, 2015 and 2014, respectively.  

Note 5. Intangible Assets  

Intangible assets consist of the following: 
Patents and trademarks 
Software development costs for internal use 

Total intangible assets 

Patents and trademarks 
Software development costs for internal use 

Total intangible assets 

March 31, 2015 

Gross  
Amount 

Accumulated  
Amortization       

Net  
Amount  

154,214     $ 
547,127       
701,341     $ 

(56,128 )   $ 
(508,392 )     
(564,520 )   $ 

98,086       
38,735       
136,821       

March 31, 2014 

Gross  
Amount 

Accumulated  
Amortization 

Net  
Amount  

154,214     $ 
547,127       
701,341     $ 

(55,712 )   $ 
(465,543 )     
(521,255 )   $ 

98,502        
81,584        
180,086        

  $ 

  $ 

  $ 

  $ 

Weighted  
Average  
Amortization  
Period (years) 
5.0 
1.0 

Weighted  
Average  
Amortization  
Period (years) 
4.9 
1.6 

Amortization expense for intangible assets for the years ended March 31, 2015 and 2014 was $43,200 and $92,200, respectively.  

Future amortization of intangible assets is approximately as follows:  

   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
    
  
    
  
  
  
  
  
  
    
  
    
    
    
  
    
    
  
  
  
    
  
  
  
    
    
  
  
    
  
  
  
  
  
    
  
  
  
  
    
    
    
  
  
    
  
  
  
F- 16 

   
Years Ending March 31, 
2016 
2017 
2018 
2019 
2020 

Note 6. Accrued Compensation and Related Expenses  

Accrued compensation and related expenses consist of the following:  

Accrued salary and wages 
Accrued paid time off 
Accrued board of director fees 
Other accrued obligations 

  $ 

  $ 

49,800   
28,200   
19,600   
19,600   
19,600   
136,80 0   

March 31,  

2015  

2014  

161,241     $ 
159,992       
401,532       
2,947       
725,712     $ 

80,328   
155,166   
214,553   
4,241   
454,288   

  $ 

  $ 

Board of director’s fees aggregating $346,700 at March 31, 2015 were paid in April 2015.  

Note 7. Notes Payable  

From December 2014 through February 2015, the Company issued to certain accredited investors 2014 Series Secured Promissory Notes 
(the “7% Bridge Notes”) in the aggregate original principal amount of $915,000. The 7% Bridge Notes accrue interest at a rate of 7% per annum. 
All principal and interest under the 7% Bridge Notes will be due on July 1, 2015, however, the Company may elect to extend the maturity date 
of the notes to January 1, 2016 by providing written notice to the note holders and a warrant to purchase a number of shares of the Company’s 
common  stock  equal  to  (a)  the  then  outstanding  principal  balance  of  the  note,  divided  by  (b)  $6.00  multiplied  by  125%.  The  Company  may 
prepay  the  7%  Bridge  Notes  at  any  time  without  penalty  and  shall  prepay  the  7%  Bridge  Notes  in  an  amount  equal  to  25%  of  the  net  cash 
proceeds received by the Company during each month from the issuance of either debt or equity.  

The 7% Bridge Notes are secured by all tangible assets of the Company pursuant to the terms of that certain Security Agreement dated 
December  3, 2014  between  the  Company and the  note  holders.  The  Company  is  obligated  to keep the  collateral  and  all  of  its  other  personal 
property and assets free and clear of all other security interests, except for certain limited exceptions.  

In  connection  with  the  issuance  of  the  7%  Bridge  Notes,  the  Company  issued  the  note  holders  warrants  to  purchase  190,625  shares  of 
common stock at an exercise price of $6.00 per share. The warrants were exercisable on May 31, 2015 and expire on November 30, 2021. The 
relative fair value of the warrants of $458,900 was recorded as a debt discount and is amortized to interest expense using the straight-line method 
which approximates the effective interest method over the term of the notes.  During the year ended March 31, 2015, the Company amortized 
$237,500 of the debt discount to interest expense for these notes.  

The Company did not pay any discounts or commissions with respect to the issuance of the 7% Bridge Notes or the warrants. In January 
and  March  2015,  the  Company  repaid  an  aggregate  of  $173,600  of  the  original  principal  balance  outstanding,  representing  25%  of  the  net 
proceeds received from the Class A and Class B convertible preferred stock offering through February 28, 2015. All remaining principal and 
accrued interest at March 31, 2015 was repaid in April 2015.  

Note 8. Convertible Debentures Payable  

2013 and 2014 Bridge Notes  

In  the  fourth  quarter  of  fiscal  2013  and  first  nine  months  of  fiscal  2014,  the  Company  issued  to  certain  accredited  investors  unsecured 
convertible  promissory  notes  (the  “Bridge  Notes”)  in  the  original  principal  amount  of  $1,294,500  and  $2,765,300,  respectively,  for  total 
principal of $4,059,800, pursuant to the terms of subscription agreements and letters of investment intent.  

F- 17 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
    
    
    
    
  
  
  
  
  
  
    
  
    
    
    
  
The Bridge Notes accrued interest at a rate of 15% per annum from date of issuance until January 31, 2013 and at a rate of 5% per annum 
from February 1, 2013 through the date of payment, in each case on a non-compounding basis. All principal and interest under the Bridge Notes 
were due on December 31, 2013.  

In connection with the issuance of  the  Bridge Notes  to  three accredited investors totaling $400,000 in June, July and  August  2013,  the 
Company granted these investors warrants to purchase 149,789 shares of common stock at an exercise prices ranging from $2.28 to $3.48 per 
share.  The  relative  fair  value  of  the  warrants  of  $199,200  was  recorded  as  a  debt  discount  and  was  amortized  to  interest  expense  using  the 
straight-line method which approximated the effective interest method over the term of the Bridge Notes. These Bridge Notes accrued interest at 
8%  per  annum  from  the  date  of  issuance  through  date  of  payment,  on  a  non-compounding  basis.  All  other  terms  of  these  Bridge  Notes  are 
consistent with the rest of the Bridge Notes. Upon conversion of the Bridge Notes in September and October 2013, the remaining unamortized 
debt discount was amortized to interest expense.  

In September and October 2013, the Bridge Note holders accepted an offer by the Company and converted an aggregate of $4,127,200 of 
outstanding principal and accrued interest under the Bridge Notes into 1,719,668 units (the “Units”) at a price of $2.40 per Unit, with each Unit 
consisting of (i) one share of common stock of the Company (“Common Stock”) and (ii) one warrant to purchase one share of Common Stock at 
an  exercise  price  of  $4.44  per  share. The  warrants  are  exercisable  beginning  on  March  31,  2015  and  have  a  term  of  five  years  from  date  of 
issuance.  As  the  transaction  was  considered  an  induced  conversion  under  the  applicable  accounting  guidance,  the  Company  recognized 
$13,713,800 in debt conversion expense representing the estimated fair value of the securities transferred in excess of the estimated fair value of 
the securities issuable upon the original conversion terms of the Bridge Notes. The Company calculated the estimated fair value of the common 
stock issued by using the closing price of the stock on the date of issuance. The estimated fair value of the warrants was calculated using Black-
Scholes.  

Upon conversion of the Bridge Notes, the remaining unamortized debt discount was amortized to interest expense. During the years ended 

March 31, 2015 and 2014, the Company amortized $0 and $199,200, respectively, to interest expense.  

5% Bridge Notes  

From December 2013 to March 2014, the Company issued to certain accredited investors unsecured convertible promissory notes in the 

original principal amount of $1,793,000.  

The  5%  Bridge  Notes  accrued  interest  at  a  rate  of  5% per  annum  from  the  date  of  issuance  through  date  of  payment,  on  a  non-

compounding basis. All principal and interest under the 5% Bridge Notes became due on June 30, 2014.  

In  connection  with  the  issuance  of  the  5%  Bridge  Notes,  the  Company  granted  these  investors  warrants  to  purchase  74,709  shares  of 
common stock at an exercise price of $5.88 per share. The warrants were exercisable on May 31, 2014 and expire on December 31, 2018. The 
relative  fair  value  of  the  warrants  of  $279,100  was  recorded  as  a  debt  discount  and  was  amortized  to  interest  expense  using  the  straight-line 
method which approximated the effective interest method over the term of the 5% Bridge Notes.  During the years ended March 31, 2015 and 
2014, the Company amortized $184,700 and $94,400, respectively, of the debt discount to interest expense for these notes.  

The agreement allowed that in the event the Company designated and issued one or more types of equity securities while the 5% Bridge 
Notes were outstanding (a “Subsequent Offering”), the Company must provide written notice to the holders of the notes and such holders had a 
right to convert up to all of the principal and accrued unpaid interest on the notes into shares of such equity securities on the same terms as the 
Subsequent Offering during the ten days following the provision of such notice. The conversion price for these equity securities was 90% of the 
offering price for the equity securities in the Subsequent Offering. At the time of issuance, the Company was unable to value the conversion 
feature of these 5% Bridge Notes given the absence of a fixed conversion rate and the convertibility of the 5% Bridge Notes was contingent upon 
the completion of a Subsequent Offering. However, on May 6, 2014, the Company completed the first convertible preferred stock offering which 
established a firm commitment date. This triggered the valuation of the beneficial conversion feature of the 5% Bridge Notes which aggregated 
$826,900  and  was  recorded  as  interest  expense  during  the  year  ended  March  31,  2015.  Note  holders  with  a  principal  amount  of  $1,743,000, 
together with $24,000 of accrued interest, converted their 5% Bridge Notes to convertible preferred stock units (see Note 11) and one note holder 
was paid principal and interest of $50,800.  

Emergent Financial Group, Inc. (“Emergent”) served as the Company’s placement agent in connection with the original placement of the 
Bridge Notes and 5% Bridge Notes and earned a commission of 9% of the original principal balance of such notes. Debt financing costs in the 
aggregate of $492,500, comprised primarily of the commission earned by Emergent, were amortized to interest expense using the straight-line 
method  which  approximated  the  effective  interest  method  over  the  term  of  the  notes.  During  the  years  ended  March  31,  2015  and  2014,  the 
Company amortized $98,400 and $385,400, respectively, of the debt financing costs to interest expense for these notes.  

F- 18 

   
   
   
   
   
   
   
   
   
   
   
  
Note 9. Related-Party Transactions  

  As of March 31, 2015 and 2014, the Company had aggregate principal balances of $1.3 million and $555,500, respectively, in outstanding 
unsecured  indebtedness  owed  to  five  related  parties,  including  four  former  members  of  the  Board  of  Directors,  representing  working  capital 
advances made to the Company from February 2001 through March 2005.  

Related-Party Convertible Notes Payable  

In March 2015, we entered into definitive agreements relating to the exchange or amendment of the notes evidencing such working capital 
advances.  Three  of  the  notes  issued  to  Patrick  Mullins,  M.D.,  Maryl  Petreccia  and  Jeffrey  Dell,  M.D.,  which  as  of  March  31,  2015  had 
outstanding  principal  balances  of  $448,200,  $266,700  and  $208,900,  respectively,  were  amended  and  the  holders  received  warrants  for  the 
purchase 37,347, 22,224, and 17,412 shares, respectively, of our common stock at an exercise price of $6.00 per share, exercisable on March 2, 
2015 and expiring on March 1, 2020, and warrants to purchase 834, 417, and 417 shares, respectively, of our common stock at an exercise price 
of  $6.00  per  share,  exercisable  on  March  2,  2015  and  expiring  on  March  1,  2020,  to  reimburse  the  three  note  holders  for  any  fees  or  other 
expenses incurred in connection with this transaction. The convertible notes, as amended, require interest payments on a calendar quarterly basis 
and all outstanding principal and accrued interest on the maturity date, which is the earlier to occur of (i) March 1, 2016, (ii) the sale of all or 
substantially all of our assets, or (iii) the merger, consolidation or other similar reorganization of the Company or an affiliate of our Company 
with another entity. Under the terms of such convertible note, upon the closing of a public offering pursuant to an effective registration statement 
under the Securities Act of 1933, as amended, resulting in at least $5,000,000 of gross cash proceeds to the Company for the sale of shares of 
common stock or includes the sale of shares of common stock among the sale of other securities, the holder has the option to convert into the 
securities issued in such offering at a twenty percent (20%) discount to the price per share (or per unit, if applicable) of the securities issued by 
the Company in such offering. The securities issued to the holder upon conversion will be restricted securities.  

One note issued to Raymond Takahashi, M.D., was exchanged for (i) a new convertible promissory note with an original principal amount 
equal to the outstanding principal and interest of the original note, and (ii) a warrant to purchase 1,490 shares of the Company’s common stock at 
an exercise price of $6.00 per share, exercisable on February 20, 2015 and expiring on February 19, 2018. The new convertible note, which as of 
March 31, 2015 had an outstanding principal balance of $35,800, requires interest payments on a calendar quarterly basis and all outstanding 
principal and accrued interest on the maturity date, which  is March 1, 2016.  Under the terms  of such convertible note, upon the closing  of a 
public offering pursuant to an effective registration statement under the Securities Act of 1933, as amended, resulting in at least $5,000,000 of 
gross cash proceeds to the Company for the sale of shares of common stock or includes the sale of shares of common stock among the sale of 
other securities, the holder has the option to convert into the securities issued in such offering at a twenty percent (20%) discount to the price per 
share (or per unit, if applicable) of the securities issued by the Company in such offering. The securities issued to the holder upon conversion 
will be restricted securities.  

The conversion of the related-party convertible notes payable at a 20% discount to the price per share of the securities issued in a public 
offering is contingent upon the closing of a public offering pursuant to an effective registration statement under the Securities Act of 1933, as 
amended, resulting in  at  least  $5,000,000 of  gross  cash  proceeds to  the Company.  The  fair  value of  the beneficial conversion  feature  will  be 
recorded upon the contingency being resolved and the Company estimated the fair value of the beneficial conversion feature of the related-party 
convertible notes aggregated $521,000 at March 31, 2015.  

The relative fair value of the related-party warrants of $280,400 was recorded as a debt discount and will be amortized to interest expense 
using the straight-line method which approximated the effective interest method over the term of the convertible notes.  During the year ended 
March 31, 2015, the Company amortized $20,800 of the debt discount to interest expense for these convertible notes.  

 Related-party interest expense under these notes was $33,500 and $36,500 for the years ended March 31, 2015 and 2014, respectively. 
Accrued  interest,  which  is  included in  related-party notes  payable in  the accompanying  consolidated balance  sheets,  amounted  to $4,600  and 
$802,600 as of March 31, 2015 and 2014, respectively.  

Related-Party Note Payable  

One note issued to Marc Grossman, M.D., which as of March 31, 2015 had an outstanding principal balance of $298,500, as amended, 
now provides for interest at a rate of 6% per annum commencing on March 13, 2015; however, no interest payments will be due if no event of 
default occurs and if the Company (i) complies with its regular payment obligations, reimburses the payee for attorneys’ fees in connection with 
the  negotiation  of  the  note  amendment,  up  to  a maximum  amount  of  $1,000,  on  the  later  of  (A) March  13,  2015,  or  (B)  three  (3)  days  after 
receiving written notice from the payee of the amount of attorneys’ fees incurred by payee, and (iii) the Company immediately pays all unpaid 
amounts due and payable in full before the earlier of May 1, 2016 or at the same time that payee(s) of any other promissory note(s) with the 
Company that were issued in 2005 are paid in full before May 1, 2016, other than (Y) notes that are satisfied upon conversion into common 
stock, warrants or any other equity of the Company, or (Z) notes that have been paid in full before March 2, 2015. All principal and interest 
under the original note, as amended by the note amendment, will be due and shall be paid on May 1, 2016. The note requires monthly payments 
of $20,000, except for the month of June 2015, where the monthly payment is $72,000.  

5% Bridge Notes  

From December 2013 to March 2014, the Company issued 5% Bridge Notes in the original principal amount of $1,793,000. This includes 
two notes in the aggregate amount of $120,000 issued to Jerrell Shelton, the Company’s Chief Executive Officer, on December 11, 2013 and 

    
   
   
   
   
   
   
   
   
   
   
   
  
January 10, 2014 as well as a note in the amount of $100,000 issued to GBR Investments, LLC on February 3, 2014, of which Richard 

Rathmann, a Director of the Company, is the manager (see Note 8).  

F- 19 

   
Class A Convertible Preferred Stock  

In  November  2014,  both  Mr.  Shelton  and  GBR  Investments,  LLC  participated  in  the  Class  A  convertible  preferred  stock  offering 
described in Note 11 and the Company issued 4,167 shares of Class A convertible preferred stock each in exchange for an aggregate amount of 
$100,000.  

Note 10. Commitments and Contingencies  

Facility and Equipment Leases  

We  lease  11,900  square  feet  of  corporate,  research  and  development,  and  warehouse  facilities  in  Lake  Forest,  California  under  an 
operating lease expiring June 30, 2015, which we do not intend to renew. In May 2015, we amended the lease to convert to a month-to-month 
basis, commencing July 1, 2015. The base rent will be $9,500 and either party will have the right to cancel this month-to-month agreement by 
giving the other party a minimum of a 90-day prior written notice. We are currently exploring other facilities to meet our growing demands. The 
lease  agreement  contains  certain  scheduled  rent  increases,  which  are  accounted  for  on  a  straight-line  basis.  We  also  lease  certain  office 
equipment which expires in March 2018.  

Future minimum lease payments are approximately as follows:  

Years ending March 31, 
2016 
2017 
2018 

Operating  
Leases 

  $ 

  $ 

27,200   
5,500   
5,500   
38,200   

Rent expense for the years ended March 31, 2015 and 2014 was approximately $168,900 and $178,000, respectively.  

Employment Agreements  

We have entered into employment agreements with certain of our officers under which payment and benefits would become payable in the 

event of termination by us for any reason other than cause, or upon a change in control of our Company, or by the employee for good reason.  

Consulting and Engineering Services  

Effective November 1, 2010, the Company entered into a Second Amendment to Master Consulting and Engineering Services Agreement 
(the  “Second  Amendment”)  with  KLATU  Networks,  LLC  (“KLATU”),  which  amended  the  Master  Consulting  and  Engineering  Services 
Agreement between the parties dated as of October 9, 2007 (the “Agreement”), as amended by the First Amendment to Master Consulting and 
Engineering Services Agreement between the parties dated as of April 23, 2009. The parties entered into the Second Amendment to clarify their 
mutual intent and understanding that all license rights granted to the Company under the Agreement, as amended, shall survive any termination 
or expiration of the Agreement. In addition, in recognition that the Company has paid KLATU less than the market rate for comparable services, 
the Second Amendment provides that if the Company terminates the Agreement without cause, which the Company has no intention of doing, or 
liquidates,  KLATU  shall  be  entitled  to  receive  additional  consideration  for  its  services  provided  from  the  commencement  of  the  Agreement 
through such date of termination, which additional compensation shall not be less than $2 million plus two times the “cost of work” (as defined 
in  the  Agreement).  Any  such  additional  compensation  would  be  payable  in  three  equal  installments  within  12  months  following  the  date  the 
amount of such additional compensation is determined. If KLATU terminates that agreement, no such payments are payable.  

The agreement provides for one year terms ending on December 31 of each year, but it automatically renews for one year periods unless 
otherwise terminated. Consulting fees for services provided by KLATU were $339,300 and $395,300 for the years ended March 31, 2015 and 
2014, respectively.  

Litigation  

The Company may become a party to product litigation in the normal course of business. The Company accrues for open claims based on 
its historical experience and available insurance coverage. In the opinion of management, there are no legal matters involving the Company that 
would have a material adverse effect upon the Company’s consolidated financial condition or results of operations.  

F- 20 

    
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
    
    
  
Indemnities and Guarantees  

The  Company  has  made  certain  indemnities  and  guarantees,  under  which  it  may  be  required  to  make  payments  to  a  guaranteed  or 
indemnified  party,  in  relation  to  certain  actions  or  transactions.  The  guarantees  and  indemnities  do  not  provide  for  any  limitation  of  the 
maximum potential future payments the Company could be obligated to make. Historically, the Company has not been obligated nor incurred 
any payments for these obligations and, therefore, no liabilities have been recorded for these indemnities and guarantees in the accompanying 
consolidated balance sheets.  

The  Company  indemnifies  its  directors,  officers,  employees  and  agents,  as  permitted  under  the  laws  of  the  States  of  California  and 
Nevada. In connection with its facility lease, the Company has indemnified its lessor for certain claims arising from the use of the facility. The 
duration of the guarantees and indemnities varies, and is generally tied to the life of the agreement.  

Note 11. Stockholders’ Equity  

Authorized Stock  

The  Company  has  20,833,333  authorized  shares  of  common  stock  with  a  par  value  of  $0.001  per  share.  In  September  2011,  our 
stockholders  approved  an  amendment  to  the  Amended  and  Restated  Articles  of  Incorporation  to  authorize  a  class  of  undesignated  or  "blank 
check" preferred stock, consisting of 2,500,000 shares at $0.001 par value per share. Shares of preferred stock may be issued in one or more 
series, with such rights, preferences, privileges and restrictions to be fixed by the Company's board of directors. In May 2014, our stockholders 
approved a Certificate of Designation, which designated 800,000 shares of preferred stock as Class A Convertible Preferred Stock. In February 
2015, the Company filed with the Secretary of State of the State of Nevada a Certificate of Designation which designated 400,000 shares of the 
Company’s previously authorized preferred stock, par value $0.001, as Class B Convertible Preferred Stock. In April 2015, the Company filed 
with the Secretary of State of the State of Nevada to increase the number shares of Class B Convertible Preferred Stock from 400,000 shares to 
585,000 shares.  

Designation of Class A Convertible Preferred Stock  

On May 2, 2014, the Company filed with the Secretary of State of the State of Nevada a Certificate of Designation which designated 
800,000  shares of the  Company’s  previously authorized preferred stock,  par  value  $0.001, as Class  A Convertible Preferred  Stock (“Class A 
Preferred Stock”).  

The rights, preferences, and privileges of the Class A Preferred Stock are summarized as follows:  

•  Dividends shall accrue on shares of Class A Preferred Stock at the rate of $0.96 per annum. Such dividends shall accrue day-to-day, 

shall be cumulative, and shall be payable on when, as, and if declared by the Board of Directors of the Company. 

• 

In the event of any voluntary or involuntary liquidation, dissolution, or winding up of the Company, holders of Class A Preferred Stock 
then outstanding shall be entitled to receive a liquidation preference payment equal to $12.00 per share (subject to appropriate 
adjustment in the event of a stock dividend, split, combination, or other similar recapitalization) plus any accrued dividends, but unpaid 
thereon, whether or not declared, together with any other dividends declared but unpaid thereon. 

•  Shares of Class A Preferred Stock shall vote together with the common stock on an as-converted basis. Holders of the Class A Preferred 
Stock will have 2.5 votes per share of Class A Preferred Stock held compared to one vote for each share of the Company’s common 
stock. 

•  At any time after September 1, 2014, shares of Class A Preferred Stock shall be convertible into 2.5 shares of common stock. In 

addition, accrued but unpaid dividends on the Preferred Stock, whether or not declared, will also be convertible into common stock after 
September 1, 2014 at the rate of one share for each $4.80 of dividend. Such conversion is subject to adjustment in the event of any stock 
split or combination, certain dividends and distributions, and any reorganization, recapitalization, reclassification, consolidation, or 
merger involving the Company. 

•  Shares of the Class A Preferred Stock shall be subject to redemption by the Company at any time on or after January 15, 2017, upon 
payment of $12.00 per share (subject to appropriate adjustment in the event of a stock dividend, split, combination, or other similar 
recapitalization) plus all accrued but unpaid dividends, whether or not declared, thereon. 

•  On March 26, 2015, the Company filed with the Secretary of State of the State of Nevada an Amended and Restated Certificate of 

Designation (“Restated Designation”). The Restated Designation adopted certain special mandatory conversion provisions for the Class 
A Preferred Stock upon a qualified offering (defined as a public offering resulting in at least $5,000,000 of gross cash proceeds), 
whereby the Class A Preferred Stock is converted into the type of securities issued in such qualified offering at a twenty percent (20%) 
discount. 

F- 21 

   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
Issuance of Class A Convertible Preferred Stock  

In  May  2014,  the  Company  entered  into  definitive  agreements  for  a  private  placement  of  its  securities  to  certain  institutional  and 
accredited investors (the “Class A Investors”) pursuant to certain subscription agreements and elections to convert between the Company and the 
Class  A  Investors.  Through  March  31,  2015,  aggregate  gross  cash  proceeds  of  $3.5  million  (approximately  $2.9  million  after  offering  costs) 
were collected  in exchange for the issuance of 291,142 shares  of  our Class A Convertible Preferred  Stock,  and  warrants,  exercisable for  five 
years, to purchase up to a total of 194,095 shares of our common stock at an exercise price of $6.00 per share. The Company intends to use the 
net proceeds for working capital purposes.  

Pursuant to the subscription agreements, the Company issued shares of a newly established Class A Convertible Preferred Stock and 
warrants to purchase common stock of Cryoport. The shares and warrants were issued as a unit (a “Unit”) consisting of (i) one share of Class A 
Convertible Preferred Stock and (ii) one warrant to purchase 0.67 shares of the Company’s common stock at an exercise price of $6.00 per share, 
which were immediately exercisable and may be exercised at any time on or before March 31, 2019.  

Pursuant to the terms of the 5% Bridge Notes issued by the Company between December 2013 and March 2014 with a total original 
principal amount of $1,793,000, the issuance of the Units to Class A Investors at $12.00 per Unit entitled the holders of the 5% Bridge Notes to 
convert up to the entire principal and accrued interest amount under the 5% Bridge Notes into Units at a rate of $10.80 per Unit. Through March 
31,  2015,  5%  Bridge  Note  holders  totaling  $1,743,000  in  original  principal  sum elected  to convert  their  5%  Bridge  Notes,  including accrued 
interest  of  $24,000,  for  Units  in  exchange  for  the  issuance  of  163,608  shares  of  our  Class  A  Convertible  Preferred  Stock  and  warrants  to 
purchase up to 109,072 shares of our common stock at an exercise price of $6.00 per share. Two of the 5% Bridge Note holders that executed 
subscription agreements to convert 5% Bridge Notes in the aggregate principal amount of $220,000 are affiliates of the Company – Jerrell W. 
Shelton,  the  Company’s  Chief  Executive  Officer,  and  GBR  Investments,  LLC,  which  is  managed  by  Richard  Rathmann,  a  Director  and 
Chairman of the Board of Directors of the Company (collectively, the “Affiliates”).  

The fair value of the beneficial conversion feature of the convertible preferred stock issuance and the relative fair value of the warrants 
issued, aggregated $3.0 million through March 31, 2015. This amount was accreted to accumulated deficit and additional paid-in capital during 
the year ended March 31, 2015.  

Emergent served as the Company’s placement agent in this transaction and received, with respect to the gross proceeds received from 
Class A Investors who converted their 5% Bridge Notes into Units (not including those conversions by the Affiliates), a commission of 3% and a 
non-accountable finance fee of 1% of such proceeds, and with respect to gross proceeds received from all other Investors, a commission of 10% 
and a non-accountable finance fee of 3% of the aggregate gross proceeds received from such Investors, plus reimbursement of legal expenses of 
up to $40,000. Emergent was issued a warrant to purchase 0.25 shares of common stock at an exercise price of $6.00 per share for each Unit 
issued in this transaction. The offering of Units to new Investors concluded on February 4, 2015.  

As of March 31, 2015, 454,750 shares of Class A Convertible Preferred Stock and 303,167 of the related warrants were outstanding for 
Class A Investors and 106,432 warrants were outstanding for Emergent in connection with the Class A Convertible Preferred Stock offering and 
the 5% Bridge Note conversions.  

No dividends have been declared as of March 31, 2015; however, the cumulative preferred stock dividend of $301,500 is included in the 

net loss attributable to common stockholders (see Note 2) and the liquidation preference.  

Designation of Class B Convertible Preferred Stock  

On  February  20,  2015,  the  Company  filed  with  the  Secretary  of  State  of  the  State  of  Nevada  a  Certificate  of  Designation  which 
designated 400,000 shares of the Company’s previously authorized preferred stock, par value $0.001, as Class B Convertible Preferred Stock 
(“Class B Preferred Stock”). On April 15, 2015, the Company filed with the Secretary of State of the State of Nevada to increase the number of 
Class B Convertible Preferred stock from 400,000 to 585,000 shares.  

The rights, preferences, and privileges of the Class B Preferred Stock are summarized as follows:  

•  Dividends shall accrue on shares of Class B Preferred Stock at the rate of $0.96 per annum. Such dividends shall accrue day-to-day, 

shall be cumulative, and shall be payable on when, as, and if declared by the Board of Directors of the Company. 

F- 22 

   
   
   
   
   
    
   
   
   
   
   
   
   
  
  
• 

In the event of any voluntary or involuntary liquidation, dissolution, or winding up of the Company, holders of Class B Preferred Stock 
then  outstanding  shall  be  entitled  to  receive  a  liquidation  preference  payment  equal  to  $12.00  per  share  (subject  to  appropriate 
adjustment in the event of a stock dividend, split, combination, or other similar recapitalization) plus any accrued dividends, but unpaid 
thereon, whether or not declared, together with any other dividends declared but unpaid thereon. 

•  Shares  of  Class  B  Preferred  Stock  shall  vote  together  with  the  common  stock  on  an  as-converted  basis.  Holders  of  the  Class  B 
Preferred Stock will have 2.5 votes per share of Class B Preferred Stock held compared to one vote for each share of the Company’s 
common stock. 

•  At any time after issuance, shares of Class B Preferred Stock shall be convertible into 2.5 shares of common stock. In addition, accrued 
but unpaid dividends on the Class B Preferred Stock, whether or not declared, will also be convertible into common stock after issuance 
at  the  rate  of  one  share  for  each  $4.80  of  dividend.  Such  conversion  is  subject  to  adjustment  in  the  event  of  any  stock  split  or 
combination,  certain  dividends  and  distributions,  and  any  reorganization,  recapitalization,  reclassification,  consolidation,  or  merger 
involving the Company. 

•  Shares of the Class B Preferred Stock shall be subject to redemption by the Company at any time on or after January 15, 2017, upon 
payment of $12.00 per share (subject to appropriate adjustment in the event of a stock dividend, split, combination, or other similar 
recapitalization) plus all accrued but unpaid dividends, whether or not declared, thereon. 

•  Shares of the Class B Preferred stock shall be subject to special mandatory conversion provisions upon a qualified offering (defined as a 
public offering resulting in at least $5,000,000 of gross cash proceeds), whereby the Class B Preferred Stock is converted into the type 
of securities issued in such qualified offering at a twenty percent (20%) discount. 

Issuance of Class B Convertible Preferred Stock  

In  February  2015,  the  Company  entered  into  definitive  agreements  for  a  private  placement  of  its  securities  to  certain  institutional  and 
accredited investors (the “Class B Investors”) pursuant to certain subscription agreements and elections to convert between the Company and the 
Class  B  Investors.  Through  March  31,  2015,  aggregate  gross  cash  proceeds  of  $1.9  million  (approximately  $1.7  million  after  offering  costs) 
were  collected  in  exchange  for  the  issuance  of  161,709 shares  of  our  Class  B Convertible  Preferred Stock,  and  warrants, exercisable  for  five 
years, to purchase up to a total of 107,806 shares of our common stock at an exercise price of $6.00 per share. The Company intends to use the 
net proceeds for working capital purposes.  

Pursuant to the subscription agreements, the Company issued shares of a newly established Class B Convertible Preferred Stock and 
warrants to purchase common stock of Cryoport. The shares and warrants were issued as a unit (a “Unit”) consisting of (i) one share of Class B 
Convertible Preferred Stock and (ii) one warrant to purchase 0.67 shares of the Company’s common stock at an exercise price of $6.00 per share, 
which were immediately exercisable and may be exercised at any time on or before May 31, 2020.  

The fair value of the beneficial conversion feature of the convertible preferred stock issuance and the relative fair value of the warrants 
issued, aggregated $1.9 million through March 31, 2015. This amount was accreted to accumulated deficit and additional paid-in capital during 
the year ended March 31, 2015.  

Emergent served as the Company’s placement agent in this transaction and received, with respect to the gross proceeds received from 
Class B Investors, a commission of 10% and a non-accountable finance fee of 3% of the aggregate gross proceeds received from such Class B 
Investors, plus reimbursement of legal expenses of up to $5,000. Emergent was issued a warrant to purchase 0.25 shares of common stock at an 
exercise price of $6.00 per share for each Unit issued in this transaction. The offering of Units to new Class B Investors will conclude on May 
18, 2015.  

As of March 31, 2015, 161,709 shares of Class B Convertible Preferred Stock and 107,806 of the related warrants were outstanding for 

Class B Investors and 38,115 warrants were outstanding for Emergent in connection with the Class B Convertible Preferred Stock offering.  

No dividends have been declared as of March 31, 2015; however, the cumulative preferred stock dividend of $3,800 is included in the net 

loss attributable to common stockholders and the liquidation preference (see Note 2).  

Common Stock Reserved for Future Issuance  

As  of  March  31,  2015, approximately  8.8 million  shares  of common  stock  were issuable  upon  conversion  or  exercise  of  rights granted 

under prior financing arrangements, preferred stock, stock options and warrants, as follows:  

F- 23 

    
   
   
   
   
   
   
   
   
    
   
   
   
   
   
  
  
  
  
Class A and B convertible preferred stock converted to common stock 
Exercise of stock options 
Exercise of warrants 
Total shares of common stock reserved for future issuances 

1,541,148   
1,793,745   
5,475,806   
8,810,699   

In August 2014 and January 2015, we issued an aggregate of 3,334 shares of restricted common stock to a consultant in exchange for 

services. The Company recognized $17,400 in stock-based compensation expense related to these shares for the year ended March 31, 2015.  

Note 12. Stock-Based Compensation  

Warrant Activity  

We typically issue warrants to purchase shares of our common stock to investors as part of a financing transaction or in connection with services 
rendered by placement agents and consultants. Included in outstanding warrants are 21,905 warrants at March 31, 2015 and 2014, respectively, 
issued to employees or directors. Our outstanding warrants expire on varying dates through November 2021. A summary of warrant activity is as 
follows:  

Outstanding — March 31, 2013 

Issued 
Exercised 
Forfeited 
Expired 

Outstanding — March 31, 2014 

Issued 
Exercised 
Expired 

Outstanding — March 31, 2015 
Vested (exercisable) — March 31, 2015 

Number of  
Shares  

3,085,600     $ 
2,103,436       
(77,193 )     
(3,311 )     
(9,004 )     
5,099,528       
826,284       
(23,256 )     
(426,750 )     
5,475,806     $ 
5,278,516     $ 

Weighted-  
Average  
Exercise  
Price/Share  

Weighted-  
Average  
Remaining  
Contractual  
Term (Years)  

Aggregate  
Intrinsic  
Value (1)  

14.16       
4.20       
2.64       
101.88       
95.52       
10.08       
6.00       
4.08       
39.36       
7.20        
7.20        

2.6     $ 
2.4     $ 

11,225,300   
10,704,400   

(1)  Aggregate intrinsic value represents the difference between the exercise price of the warrant and the closing market price of the common 

stock on March 31, 2015, which was $8.64 per share. 

The following table summarizes information with respect to warrants outstanding and exercisable at March 31, 2015:  

Exercise Price  
$ 
$ 
$ 
$ 
$ 

  2.28 – 2.40       
  2.52 – 4.44       
  4.56 – 8.28       
 8.40 – 11.04       
11.16 – 129.60       

Number  

Outstanding      
198,965       
1,729,315       
1,734,819       
1,785,964       
26,743       
5,475,806       

Weighted-  
Average  
Remaining  
Contractual  
Life (Years)      

3.3 
3.5 
3.0 
0.7 
2.2 

F- 24 

Weighted-  
Average  
Exercise Price     
2.40       
4.44       
7.20       
9.24       
85.92       

    $ 
    $ 
    $ 
    $ 
    $ 

Weighted-  
Average  
Exercise Price   
2.40   
4.44   
7.20   
9.24   
85.92   

Number  
Exercisable      

198,965     $ 
1,729,315     $ 
1,537,529     $ 
1,785,964     $ 
26,743     $ 
5,278,516       

   
   
   
   
   
   
   
   
   
   
  
    
    
    
     
  
  
    
    
    
  
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
     
     
    
  
        
  
      
        
    
Stock Options  

We have three stock incentive plans: the 2002 Stock Incentive Plan (the “2002 Plan”), the 2009 Stock Incentive Plan (the “2009 Plan”) 
and  the  2011  Stock  Incentive  Plan  (the  “2011  Plan”),  (collectively,  the  “Plans”).  The  2002  Plan  expired  and  no  options  have  been  granted 
pursuant the 2002 Plan or 2009 Plan subsequent to the adoption of the 2011 Plan. On September 6, 2013 the stockholders approved an increase 
to the number of shares of the Company’s common stock available for issuance under the 2011 Plan by 591,667 shares. On August 29, 2014 the 
stockholders  approved an increase  to the number of shares  of  the  Company’s  common  stock available for  issuance by 125,000 shares. As  of 
March 31, 2015, the Company has 25,314 shares and 157,482 available for future awards under the 2009 Plan and the 2011 Plan, respectively. In 
December 2014, 262,500 options were granted outside the plan to Jerrell Shelton, the Company’s Chief Executive Officer.  

During each of the two years in the period ended March 31, 2015, we granted stock options at exercise prices equal to or greater than the 
quoted market price of our common stock on the grant date. The fair value of each option grant was estimated on the date of grant using Black-
Scholes with the following weighted average assumptions:  

Expected life (years) 
Risk-free interest rate 
Volatility 
Dividend yield 

March 31, 

2015  
1.5 – 6.1 

2014  
1.6 – 6.0 

     0.31% - 2.03 % 
     103% - 128% 

     0.19% - 1.84% 
     127% - 140 % 

0% 

0% 

The expected option life assumption is estimated based on the simplified method. Accordingly, the Company has utilized the average of 
the contractual term of the options and the weighted average vesting period for all options to calculate the expected option term. The risk-free 
interest rate  assumption is based upon observed interest rates appropriate for the expected term of  our employee stock options.  The expected 
volatility is based on the historical volatility of our stock commensurate with the expected life of the stock-based award. We do not anticipate 
paying dividends on the common stock in the foreseeable future.  

We  recognize  stock-based  compensation  cost  over  the  vesting  period  using  the  straight-line  single  option  method.  Stock-based 
compensation expense is recognized only for those awards that are ultimately expected to vest. An estimated forfeiture rate has been applied to 
unvested  awards  for  the  purpose  of  calculating  compensation  cost.  The  estimated  forfeiture  rate  of  0%  per  year  is  based  on  the  historical 
forfeiture  activity  of  unvested  stock  options.  These  estimates  are  revised,  if  necessary,  in  future  periods  if  actual  forfeitures  differ  from  the 
estimates. Changes in forfeiture estimates impact compensation cost in the period in which the change in estimate occurs.  

A summary of stock option activity is as follows:    

Weighted-  
Average  
Exercise  

Price/Share       

Weighted-  
Average  
Remaining  
Contractual  
Term (Years)       

Aggregate  
Intrinsic  
Value (1)  

Number of  
Shares  

Outstanding — March 31, 2013 

Granted (weighted-average fair value of $2.88 per 

424,645     $ 

5.64       

share) 
Exercised 
Forfeited 
Expired 

Outstanding — March 31, 2014 

Granted (weighted-average fair value of $4.20 per 

share) 
Exercised 
Forfeited 
Expired 

Outstanding — March 31, 2015 
Vested (exercisable) — March 31, 2015 
Unvested (unexercisable) — March 31, 2015 

639,439       
(54,750 )     
(16,484 )     
(1,667 )     
991,183       

955,199       
(657 )     
(150,130 )     
(1,850 )     
1,793,745     $ 
686,849     $ 
1,106,897     $ 

3.36       
2.40       
3.84       
72.00       
4.20       

4.92       
3.24       
4.56       
27.48       
4.56        
4.68        
4.44        

8.3     $ 
6.8     $ 
3.3     $ 

7,761,500   
3,119,200   
4,642,300   

(1)  Aggregate intrinsic value represents the difference between the exercise price of the option and the closing market price of the common 

stock on March 31, 2015, which was $8.64 per share. 

F- 25 

   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
    
  
    
      
  
    
    
  
  
    
  
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
    
        
    
     
     
     
The following table summarizes information with respect to stock options outstanding and exercisable at March 31, 2015:  

Exercise Price  
$ 
$ 
$ 
$ 
$ 

2.04 – 4.68       
4.80 – 6.24       
6.36 – 11.76       
12.60 – 26.40       
51.60 – 99.72        

Number  

Outstanding       
856,959       
835,501       
90,103       
4,467       
6,715       
1,793,745       

Weighted-  
Average  
Remaining  
Contractual  
Life (Years)       
7.8 
9.4 
4.7 
5.4 
1.5 

    $ 
    $ 
    $ 
    $ 
    $ 

Weighted-  
Average  
Exercise  
Price  

Number  

Exercisable       

Weighted-  
Average  
Exercise  
Price  

3.36       
4.92       
7.92       
19.44       
55.44        

473,531     $ 
121,676     $ 
80,772     $ 
4,155     $ 
6,715     $ 
686,849       

3.12   
5.16   
8.04   
19.68   
55.44   

As of March 31, 2015, there was unrecognized compensation expense of $4.2 million related to unvested stock options, which we expect 

to recognize over a weighted average period of 3.3 years.  

Note 13. Income Taxes  

Significant components of the Company’s deferred tax assets as of March 31, 2015 and 2014 are shown below:  

Deferred tax assets: 
Net operating loss carryforward 
Research credits 
Expenses recognized for granting of options and warrants 
Accrued expenses and reserves 
Valuation allowance 

March 31,  

2015  

2014  

(000’s) 

  $ 

  $ 

16,830     $ 
56       
1,554       
20       
(18,460 )     
—    $ 

15,379   
60   
1,651   
135   
(17,225 ) 
—  

Based on the weight of available evidence, the Company’s management has determined that it is more likely than not that the net deferred 

tax assets will not be realized. Therefore, the Company has recorded a full valuation allowance against the net deferred tax assets. The 
Company’s income tax provision consists of state minimum taxes.  

The income tax provision differs from that computed using the federal statutory rate applied to income before taxes as follows:  

Computed tax benefit at federal statutory rate 
State tax, net of federal benefit 
Warrant MTM Adjustment 
Induced conversion costs 
Interest expense 
Permanent items and other 
Valuation allowance 

March 31, 

2015  
(2,382,000 )   $ 
(187,000 )     
—      
—      
462,000       
873,600       
1,235,000       
1,600     $ 

  $ 

  $ 

2014  
(6,650,000 ) 
(327,000 ) 
(7,000 ) 
4,663,000   
—  
4,600   
2,318,000   
1,600   

At  March  31,  2015,  the  Company  has  federal  and  state  net  operating  loss  carryforwards  of  approximately  $43,386,000  and  $36,057,000 
which will begin to expire in 2019, unless previously utilized, and as of 2012 have already begun to for state carryforwards. At March 31, 2015, 
the Company has federal and California research and development tax credits of approximately $18,000 and $58,000, respectively. The federal 
research tax credit begins to expire in 2026 unless previously utilized and the California research tax credit has no expiration date.  

Utilization of the net operating loss and research and development carryforwards might be subject to a substantial annual limitation due to 
ownership change limitations that may have occurred or that could occur in the future, as required by Section 382 of the Internal Revenue Code 
of 1986, as amended (the “Code”), as well as similar state and foreign provisions. These ownership changes may limit the amount of NOL and 
R&D credit carryforwards that can be utilized annually to offset future taxable income and tax, respectively. In general, an “ownership change”
as  defined  by  Section 382  of  the  Code  results  from  a  transaction  or  series  of  transactions  over  a  three-year  period  resulting  in  an  ownership 
change of more than 50 percentage points of the outstanding stock of a company by certain stockholders or public groups. Since the Company’s 
formation,  the  Company  has  raised  capital  through  the  issuance  of  capital  stock  on  several  occasions  which,  combined  with  the  purchasing 
stockholders’ subsequent disposition of those shares, may have resulted in such an ownership change, or could result in an ownership change in 

   
   
   
   
   
   
   
   
   
   
   
   
  
    
    
  
  
         
  
      
         
    
  
  
  
  
  
    
  
    
    
    
        
    
    
    
    
    
  
  
  
  
  
  
    
  
    
    
    
    
    
    
  
the future upon subsequent disposition.  

F- 26 

   
The  Company  has  not  completed  a  study  to  assess  whether  an  ownership  change  has  occurred.  If  the  Company  has  experienced  an 
ownership change, utilization of the NOL or R&D credit carryforwards would be subject to an annual limitation under Section 382 of the Code, 
which is determined by first multiplying the value of the Company’s stock at the time of the ownership change by the applicable long-term, tax-
exempt rate, and then could be subject to additional adjustments, as required. Any limitation may result in expiration of a portion of the NOL or 
R&D credit carryforwards before utilization. Further, until a study is completed and any limitation is known, no amounts are being considered as 
an  uncertain  tax  position  or  disclosed  as  an  unrecognized  tax  benefit.  Due  to  the  existence  of  the  valuation  allowance,  future  changes  in  the 
Company’s unrecognized tax benefits will not impact its effective tax rate. Any carryforwards that will expire prior to utilization as a result of 
such limitations will be removed from deferred tax assets with a corresponding reduction of the valuation allowance.  

On  September  13,  2013,  the  U.S.  Treasury  Department  released  final  income  tax  regulations  on  the  deduction  and  capitalization  of 
expenditures related to tangible property. These final regulations apply to tax years beginning on or after January 1, 2014. The Company adopted 
the tax treatment of expenditures to improve tangible property and the capitalization of inherently facilitative costs to acquire tangible property 
as of April 1, 2014. The tangible property regulations required the Company to make additional tax accounting method changes as of April 1, 
2014; however, the impact of these changes was not material to the Company’s consolidated financial position, its results of operations or its 
footnote disclosures.  

Note 14. Quarterly Financial Data (Unaudited)  

A summary of quarterly financial data is as follows ($ in ‘000’s):  

Year ended March 31, 2015 
Total revenues 
Gross margin 
Operating loss 
Net loss 
Net loss per share attributable to common stockholders - 

basic and diluted 

Year ended March 31, 2014 
Total revenues 
Gross margin 
Operating loss 
Net  loss 
Net loss per share attributable to common stockholders - 

basic and diluted 

  $ 
  $ 
  $ 
  $ 

  $ 

  $ 
  $ 
  $ 
  $ 

  $ 

June 30  

     September 30        December 31        March 31  

Quarter Ended  

937     $ 
339     $ 
(1,168 )   $ 
(2,297 )   $ 

825     $ 
225     $ 
(1,375 )   $ 
(1,385 )   $ 

975     $ 
235     $ 
(1,357 )   $ 
(1,408 )   $ 

(0.61 )   $ 

(0.64 )   $ 

(0.40 )   $ 

488     $ 
55     $ 
(1,260 )   $ 
(1,324 )   $ 

580     $ 
72     $ 
(1,287 )   $ 
(14,960 )   $ 

757     $ 
167     $ 
(1,257 )   $ 
(1,840 )   $ 

(0.42 )   $ 

(4.59 )   $ 

(0.37 )   $ 

1,198   
370   
(1,693 ) 
(1,937 ) 

(0.79 ) 

835   
143   
(1,274 ) 
(1,441 ) 

(0.29 ) 

Earnings  per basic and diluted  shares are  computed independently  for  each of  the  quarters presented based  on  basic  and  diluted  shares 

outstanding per quarter and, therefore, may not sum to the totals for the year.  

Note 15. Subsequent Events  

From  April  6,  2015  to  May  18,  2015,  the  Company  issued  additional  shares  of  the  Class  B  Convertible  Preferred  Stock  to  Class  B 
Investors.  Gross  proceeds  of  $4.2  million  (approximately  $3.6  million  after  offering  costs)  were  collected  in  exchange  for  the  issuance  of 
347,637 shares of our Class B Convertible Preferred Stock, and warrants, exercisable for five years, to purchase up to a total of 231,758 shares of 
our common stock at an exercise price of $6.00 per share. In May 2015, Mrs. Richard Berman, spouse of a board member, participated in the 
Class B Convertible Preferred Stock offering and the Company issued 1,667 shares of Class B convertible preferred stock each in exchange for 
an aggregate amount of $20,000. The Company intends to use the net proceeds for working capital purposes.  

On May 7, 2015, the Company granted employees and members of the board of director’s options to purchase 465,625 and 20,834 shares 
of common stock, respectively, with an exercise price of $7.80 per share, of which 355,000 shares were issued outside of a plan. The exercise 
price for the shares of common stock pursuant to the option is equal to the fair market value of the Company’s common stock on the date of 
grant.  

F- 27 

   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
  
    
        
        
        
    
    
        
        
        
    
Exhibit  
No.  

Index to Exhibits  

Description  

3.1 

   Amended and Restated Articles of Incorporation of the Company, as amended.  Incorporated by reference to Exhibit 3.1 to the 

Company’s Quarterly Report on Form 10-Q for the Quarter Ended September 30, 2012. 

3.2 

   Amended and Restated Bylaws of the Company.  Incorporated by reference to Exhibit 3.2 of the Company’s Current Report on 

Form 8-K dated October 23, 2012. 

3.3 

   Cryoport Systems, Inc. 2002 Stock Incentive Plan adopted by the Board of Directors on October 1, 2002.  Incorporated by 

reference to Exhibit 3.13 to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

3.4 

   Amended and Restated Certificate of Designation of Class A Preferred Stock. Incorporated by reference to Exhibit 3.1 of the 

Company’s Current Report on Form 8-K dated March 26, 2015. 

3.5 

   Certificate of Designation of Class B Preferred Stock. Incorporated by reference to Exhibit 3.1 of the Company’s Current Report on 

Form 8-K dated February 20, 2015. 

3.6 

   Amendment to Certificate of Designation of Class B Preferred Stock.  Incorporated by reference to Cryoport’s Amendment No. 1 

to Registration Statement on Form S-1 dated April 17, 2015 and referred to as Exhibit 3.6. 

3.7+ 

   Certificate of Change filed with the Nevada Secretary of State on May 12, 2015. 

4.1 

   Form of Common Stock Purchase Warrant dated September 28, 2007. Incorporated by reference to Cryoport’s Registration 

Statement on Form SB-2 dated November 9, 2007. 

4.2 

   Common Stock Purchase Warrant dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 

June 9, 2008. 

4.3 

   Common Stock Purchase Warrant dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 

June 9, 2008. 

4.4 

   Form of Warrant and Warrant Certificate in connection with the February 25, 2010 public offering. Incorporated by reference to 

Cryoport’s Amendment No. 5 to Form S-1/A Registration Statement dated February 9, 2010. 

4.5 

   Form of Securities Purchase Agreement in connection with the August to October 2010 private placement. Incorporated by 

reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.6 

   Form of First Amendment to Security Purchase Agreement in connection with the August to October 2010 private placement. 

Incorporated by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.7 

   Form of Securities Purchase Agreement (Continuation of the Placement) in connection with the August to October 2010 private 

placement. Incorporated by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.8 

   Registration Rights Agreement in connection with the August to October 2010 private placement. Incorporated by reference to 

Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.9 

   Form of Joinder to Registration Rights Agreement in connection with the August to October 2010 private placement. Incorporated 

by reference to Cryoport’s Registration Statement on Form S-1 dated October 19, 2010. 

4.10 

4.11 

   Form of Securities Purchase Agreement in connection with the February 2011 private placement. Incorporated by reference to 

Cryoport’s Registration Statement on Form S-1 dated April 1, 2011. 

   Form of Registration Rights Agreement in connection with the February 2011 private placement. Incorporated by reference to 

Cryoport’s Registration Statement on Form S-1 dated April 1, 2011.  

   
   
  
  
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
  
     
     
  
   
  
Exhibit  
No.  

Description  

4.12 

  Form of Warrant in connection with the August to October 2010 private placement. Incorporated by reference to Cryoport’s 

Registration Statement on Form S-1/A dated April 22, 2011. 

4.13 

  Form of Warrant in connection with the February 2011 private placement. Incorporated by reference to Cryoport’s Registration 

Statement on Form S-1/A dated April 22, 2011. 

4.14 

  Form of Securities Purchase Agreement. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC 

on February 24, 2012. 

4.15 

  Form of Registration Rights Agreement. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC 

on February 24, 2012. 

4.16 

4.17 

  Form of Warrant. Incorporated by reference to Cryoport’s Current Report on Form 8-K filed with the SEC on February 24, 2012. 

  Form of Warrant issued with Convertible Promissory Notes.  Incorporated by reference to Exhibit 4.20 of Cryoport’s Quarterly 

Report on Form 10-Q for the Quarter Ended September 30, 2013. 

4.18 

  Form of Warrant issued upon Conversion of Convertible Promissory Notes.  Incorporated by reference to Exhibit 4.21 of 

Cryoport’s Quarterly Report on Form 10-Q for the Quarter Ended September 30, 2013. 

4.19 

  Form of Warrant Issued to Placement Agents.  Incorporated by reference to Exhibit 4.22 of Cryoport’s Quarterly Report on Form 

10-Q for the Quarter Ended September 30, 2013. 

4.20 

  Form of Warrant issued with Convertible Promissory Notes (5% Bridge Notes).  Incorporated by reference to Exhibit 4.23 of 

Cryoport’s Quarterly Report on Form 10-Q for the Quarter Ended December 31, 2013. 

4.21 

  Form of Warrant issued in connection with the May 2014 private placement. Incorporated by reference to Exhibit 4.24 of 

Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2014. 

4.22 

  Warrant to Purchase Common Stock. Incorporated by reference to Exhibit 4.1 of the Company’s Current Report on Form 8-K dated 

December 9, 2014. 

4.23 

  Warrant to Purchase Common Stock. Incorporated by reference to Exhibit 4.1 of the Company’s Current Report on Form 8-K dated 

February 20, 2015. 

4.24 

  Form of Warrant issued in connection with the Exchange and Investment Agreement. Incorporated by reference to Exhibit 4.1 of 

the Company’s Current Report on Form 8-K dated March 9, 2015. 

4.25 

  Form of March Warrant issued in connection with the Investment Agreement. Incorporated by reference to Exhibit 4.2 of the 

Company’s Current Report on Form 8-K dated March 9, 2015. 

4.26 

  Form of March Fee Warrant issued in connection with the Investment Agreement. Incorporated by reference to Exhibit 4.3 of the 

Company’s Current Report on Form 8-K dated March 9, 2015. 

10.1.1 

  Commercial Promissory Note between Cryoport, Inc. and D. Petreccia executed on August 26, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.2 

  Commercial Promissory Note between Cryoport, Inc. and J. Dell executed on September 1, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.3 

  Commercial Promissory Note between Cryoport, Inc. and P. Mullens executed on September 2, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

10.1.4 

  Commercial Promissory Note between Cryoport, Inc. and R. Takahashi executed on August 25, 2005. Incorporated by reference to 

Cryoport’s Registration Statement on Form 10-SB/A4 dated February 23, 2006. 

   
   
  
  
  
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
    
    
  
    
  
    
  
    
  
Exhibit  
No.  

Description  

10.2.1 

  Lease Agreement dated June 26, 2007 between CryoPort, Inc. and Viking Investors—Barents Sea LLC. Incorporated by reference 

to CryoPort’s Quarterly Report on Form 10-QSB for the quarter ended June 30, 2007 and referred to as Exhibit 10.5 

10.2.2 

  Second Amendment To Lease: Renewal dated August 24, 2009, between CryoPort, Inc. and Viking Inventors-Barents Sea LLC. 

Incorporated by reference to Cryoport’s Amendment No. 1 to Form S-1/A Registration Statement dated January 12, 2010. 

10.2.3 

  Third Amendment to Lease: Renewal dated June 8, 2010 between Viking Investors Barents Sea, LLC. Incorporated by reference to 

Exhibit 10.5.3 to Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2013. 

10.3 

10.4 

10.5 

10.6 

  Securities Purchase Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form 

SB-2 dated November 9, 2007 and referred to as Exhibit 10.6. 

  Registration Rights Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form 

SB-2 dated November 9, 2007 and referred to as Exhibit 10.7. 

  Security Agreement dated September 27, 2007. Incorporated by reference to Cryoport’s Registration Statement on Form SB-2 dated 

November 9, 2007 and referred to as Exhibit 10.8. 

  Securities Purchase Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 

June 9, 2008 and referred to as Exhibit 10.10. 

10.7 

  Registration Rights Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated 

June 9, 2008 and referred to as Exhibit 10.11. 

10.8 

  Waiver dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 2008 and referred 

to as Exhibit 10.12. 

10.9 

  Security Agreement dated May 30, 2008. Incorporated by reference to Cryoport’s Current Report on Form 8-K dated June 9, 2008 

and referred to as Exhibit 10.13. 

10.10 

  Consent, Waiver and Agreement with Enable Growth Partners LP, Enable Opportunity Partners LP, Pierce Diversified Strategy 

Master Fund LLC, Ena, BridgePointe Master Fund Ltd. and Cryoport Inc. and its subsidiary dated July 30, 2009. Incorporated by 
reference to Cryoport’s Current Report on Form 8-K dated July 29, 2009 and referred to as Exhibit 10.15. 

10.11.1 

  Master Consulting and Engineering Services Agreement dated October 9, 2007 with KLATU Networks, LLC and CryoPort, Inc. 

Incorporated by reference to Cryoport, Inc.’s Registration Statement on Form S-8 dated March 25, 2009 and referred to as Exhibit 
10.2. 

10.11.2 

  First Amendment to Master Consulting and Engineering Services Agreement dated as of April 23, 2009, between CryoPort, Inc. 

and KLATU Networks, LLC. Incorporated by reference to Cryoport’s Registration Statement on Form S-1/A dated December 17, 
2010 and referred to as Exhibit 10.32. 

10.11.3 

  Second Amendment to Master Consulting and Engineering Services Agreement dated as of November 1, 2010, between CryoPort, 
Inc. and KLATU Networks, LLC. Incorporated by reference to Cryoport’s Registration Statement on Form S-1/A dated December 
17, 2010 and referred to as Exhibit 10.33. 

10.12 

  Stock Option Agreement ISO under the 2002 Stock Incentive Plan of Cryoport Systems, Inc. Incorporated by reference to Exhibit 

3.14 to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

10.13 

  Stock Option Agreement NSO under the 2002 Stock Incentive Plan of Cryoport Systems, Inc. Incorporated by reference to Exhibit 

3.15 to the Company’s Registration Statement on Form 10-SB/A2 dated January 26, 2006. 

10.14 

  2009 Stock Incentive Plan of the Company.  Incorporated by reference to Exhibit 10.21 of the Company’s Current Report on Form 

8-K dated October 15, 2009 and referred to as Exhibit 10.21. 

   
   
  
  
  
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
Exhibit  
No.  

Description 

10.15 

  Form Incentive Stock Option Award Agreement under the 2009 Stock Incentive Plan of the Company. Incorporated by reference to 

Exhibit 10.22 of the Company’s Current Report on Form 8-K dated October 9, 2009. 

10.16 

  Form of Non-Qualified Stock Option Award Agreement under the 2009 Stock Incentive Plan of the Company. Incorporated by 

reference to Exhibit 10.25 of the Company’s Registration Statement on Form S-8 dated April 27, 2010. 

10.17 

  2011 Stock Incentive Plan (as amended and restated).  Incorporated by reference to Exhibit B of the Company’s Definitive Proxy 

Statement on Schedule 14A filed with the SEC on July 30, 2012. 

10.18 

  Form of Stock Option Award Agreement. Incorporated by reference to Exhibit 10.37 to Cryoport’s Current Report on Form 8-K 

filed with the SEC on September 27, 2011. 

10.19 

  Form of Non-Qualified Stock Option Award Agreement. Incorporated by reference to Exhibit 10.38 to Cryoport’s Current Report 

on Form 8-K filed with the SEC on September 27, 2011. 

10.20 

  Form of Convertible Promissory Note. Incorporated by reference to Exhibit 10.24 to Cryoport’s Annual Report on Form 10-K filed 

with the SEC on June 25, 2013. 

10.21 

  Form of Amendment to Convertible Promissory Note. Incorporated by reference to Exhibit 10.25 to Cryoport’s Annual Report on 

Form 10-K filed with the SEC on June 25, 2013. 

10.22 

  Form of Convertible Promissory Note. Incorporated by reference to Exhibit 10.26 to Cryoport’s Annual Report on Form 10-K filed 

with the SEC on June 25, 2013. 

10.23* 

  Employment Agreement between the Company and Jerrell Shelton.  Incorporated by reference to the Company’s Current Report on 

Form 8-K filed on November 6, 2012 and referred to as Exhibit 10.45. 

10.24* 

  Stock Option Agreement dated November 5, 2012 between the Company and Jerrell Shelton. Incorporated by reference to Exhibit 

10.28 to Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2013. 

10.25# 

  Master Agreement between the Company and Federal Express Corporation dated January 1, 2013.  Incorporated by reference to the 

Company’s Current Report on Form 8-K filed on January 8, 2013 and referred to as Exhibit 10.1. 

10.26* 

  Employment Agreement dated June 28, 2013 with Jerrell Shelton.  Incorporated by reference to Exhibit 10.30 to Cryoport’s Current 

Report on Form 8-K filed with the SEC on July 3, 2013. 

10.27 

  Form of Convertible Promissory Notes issued with Warrants.  Incorporated by reference to Exhibit 10.31 to Cryoport’s Quarterly 

Report on Form 10-Q for the Quarter Ended September 30, 2013. 

10.28 

  Form of Letter of Tender and Exchange.  Incorporated by reference to Exhibit 10.32 to Cryoport’s Quarterly Report on Form 10-Q 

for the Quarter Ended September 30, 2013. 

10.29 

  Form of Convertible Promissory Note (5% Bridge Note) issued with Warrants.  Incorporated by reference to Exhibit 10.33 to 

Cryoport’s Quarterly Report on Form 10-Q for the Quarter Ended December 31, 2013. 

10.30 

  Form of Subscription Agreement in connection with the May 2014 private placement. Incorporated by reference to Exhibit 10.34 to 

Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2014. 

10.31 

  Form of Election to Convert in connection with the May 2014 private placement. Incorporated by reference to Exhibit 10.35 to 

Cryoport’s Annual Report on Form 10-K filed with the SEC on June 25, 2014. 

10.32 

  Form of Indemnification Agreement. Incorporated by reference to Exhibit 10.1 to Cryoport’s Current Report on Form 8-K filed 

with the SEC on July 16, 2014. 

10.33 

  Subscription Agreement and Letter of Investment Intent. Incorporated by reference to Exhibit 10.1 to Cryoport’s Current Report on 

Form 8-K filed with the SEC on December 9, 2014. 

   
   
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
Exhibit  
No.  

Description  

10.34 

  2014 Series Secured Promissory Note. Incorporated by reference to Exhibit 10.2 to Cryoport’s Current Report on Form 8-K filed 

with the SEC on December 9, 2014. 

10.35 

  Security Agreement. Incorporated by reference to Exhibit 10.3 to Cryoport’s Current Report on Form 8-K filed with the SEC on 

December 9, 2014. 

10.36 

  Subscription Agreement and Letter of Investment Intent. Incorporated by reference to Exhibit 10.1 to Cryoport’s Current Report on 

Form 8-K filed with the SEC on February 20, 2015. 

10.37 

  Form of Note Exchange Agreement and Letter of Investment Intent, dated February 19, 2015. Incorporated by reference to Exhibit 

10.1 to Cryoport’s Current Report on Form 8-K filed with the SEC on March 9, 2015. 

10.38 

  Form of Exchange Note issued in connection with the Exchange and Investment Agreement. Incorporated by reference to Exhibit 

10.2 to Cryoport’s Current Report on Form 8-K filed with the SEC on March 9, 2015. 

10.39 

  Form of Letter of Investment Intent, dated March 2, 2015. Incorporated by reference to Exhibit 10.3 to Cryoport’s Current Report 

on Form 8-K filed with the SEC on March 9, 2015. 

10.40 

  Form of Amended and Restate Note issued in connection with the Exchange and Investment Agreement. Incorporated by reference 

to Exhibit 10.4 to Cryoport’s Current Report on Form 8-K filed with the SEC on March 9, 2015. 

10.41 

  Amendment to Simple Interest Commercial Promissory Note, dated March 2, 2015. Incorporated by reference to Exhibit 10.5 to 

Cryoport’s Current Report on Form 8-K filed with the SEC on March 9, 2015 

10.42*+ 

  Stock Option Agreement dated December 18, 2014 between the Company and Jerrell Shelton. 

21+ 

  Subsidiaries of Registrant. 

23.1+ 

  Consent of Independent Registered Public Accounting Firm—KMJ Corbin & Company LLP. 

31.1+ 

  Certification of Principal Executive Officer, pursuant to Rule 13a-14(a)/15d-14(a) of the Securities Exchange Act of 1934. 

31.2+ 

  Certification of Principal Financial Officer, pursuant to Rule 13a-14(a)/15d-14(a) of the Securities Exchange Act of 1934. 

32.1+ 

  Certification of Principal Executive Officer, pursuant to Rule 13a-14(b)/15d-14(b) of the Securities Exchange Act of 1934 and 

18 U.S.C. Section 1350. 

32.2+ 

  Certification of Principal Financial Officer, pursuant to Rule 13a-14(b)/15d-14(b) of the Securities Exchange Act of 1934 and 

18 U.S.C. Section 1350. 

101.INS+    XBRL Instance Document. 

101.SCH+    XBRL Taxonomy Extension Schema Document. 

101.CAL+   XBRL Taxonomy Extension Calculation Linkbase Document. 

101.DEF+    XBRL Taxonomy Extension Definition Linkbase Document. 

101.LAB+   XBRL Taxonomy Extension Label Linkbase Document. 

101.PRE+    XBRL Taxonomy Extension Presentation Linkbase Document. 

   
   
  
  
  
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
* 

# 

Indicates a management contract or compensatory plan or arrangement. 

Confidential portions omitted and filed separately with the U.S. Securities and Exchange Commission pursuant to Rule 24b-2 promulgated 
under the Securities Exchange Act of 1934, as amended. 

+ 

Filed herewith. 

   
   
   
   
   
  
  
EXHIBIT 3.7 

   
   
  
   
  
   
   
  
  
   
   
  
  
STOCK OPTION AGREEMENT  

EXHIBIT 10.42 

This  Stock  Option  Agreement  (“Agreement”)  is  between  Cryoport,  Inc.  (“Company”)  and  Jerrell  Shelton  (the  “Optionee”),  and  is 

effective as of December 18, 2014 (“Grant Date”).  

AGREEMENT  

In consideration of the mutual covenants and conditions hereinafter set forth and for other good and valuable consideration, the receipt 

and sufficiency of which are hereby acknowledged, the Company and the Optionee agree as follows:  

1.  Grant of Option . Subject to the terms of this Agreement, the Company grants to the Optionee the right and option to purchase from 
the Company all or any part of an aggregate of 3,150,000 shares of the Common Stock of the Company (“Option”). The Option granted under 
this  Agreement  is  not  intended  to  be  an  “incentive  stock  option”  under  Section  422  of  the  Internal  Revenue  Code  of  1986,  as  amended  (the 
“Code”).  

2.   Purchase  Price  .  The  purchase  price  under  this  Agreement  is  $0.40  ,  the  per  share  closing  price  the  of  Common  Stock  of  the 

Company (“Stock”) on the Grant Date, which is equal to the fair market value of a share of Stock on the Grant Date.  

3.  Vesting of Option . The Option shall vest and be exercisable according to the following schedule:  

1/48 of the options vest on the 18 th of each month for forty eight months beginning on 1/18/2015 and ending on 12/18/2019 

Provided  that  such  vesting  will  be  accelerated  on  the  date  that  the  Company  files  a  Form  10-Q  or  Form  10-K  indicating  an  income  from 
operations for the Company in two consecutive fiscal quarters;  

Provided further, that, pursuant to Section 13 below, such vesting will be accelerated in the event of a Change of Control (as defined in Section 
13).  

4.  Exercise of Option . This Option may be exercised, to the extent vested (under Section 3 above), in whole or in part at any time 
before the Option expires by delivery of a written notice of exercise (under Section 6 below) and payment of the purchase price in cash or such 
other  method  permitted  by  the  Compensation  Committee  of  the  Board  of  Directors  of  the  Company  (the  “Committee”)  under  Section  5  and 
communicated to the Optionee before the date the Optionee exercises the Option.  

5.  Payment . The Committee may determine methods other than cash by which the exercise price of the Option may be paid, the form 
of payment, including, without limitation, cash, promissory note, shares of Stock held for longer than six months (through actual tender or by 
attestation),  any  net-issuance  arrangement  or  other  property  acceptable  to  the  Committee  (including  broker-assisted  “cashless  exercise”
arrangements), and the methods by which shares of Stock shall be delivered or deemed to be delivered to the Optionee.  

   
   
   
   
   
   
   
   
   
   
   
   
   
  
6.   Method  of  Exercising  Option  .  Subject  to  the  terms  of  this  Agreement,  the  Option  may  be  exercised  by  timely  delivery  to  the 
Company of written notice, which notice shall be effective on the date received by the Company. The notice shall state the Optionee’s election to 
exercise the Option and the number of underlying shares in respect of which an election to exercise has been made. Such notice shall be signed 
by the Optionee, or if the Option is exercised by a person or persons other than the Optionee because of the Optionee’s death, such notice must 
be signed by such other person or persons and shall be accompanied by proof acceptable to the Company of the legal right of such person or 
persons to exercise the Option.  

7.   Registration  .  The  Company  shall  use  its  commercially  reasonable  efforts  to  file  a  registration  statement  on  Form  S-3  under  the 
Securities Act of 1933, as amended, covering the resale of the Stock and will use its commercially reasonable efforts to cause such registration 
statement to be declared effective as soon as practicable.  

8.  Term of Option . The Option granted under this Agreement expires at the earlier of (a) ten (10) years from the Grant Date, through 
and including the normal close of business of the Company on the tenth (10 th ) anniversary of the Grant Date, and (b) ninety (90) days after the 
resignation and/or removal of the Optionee as an employee of the Company, through and including the normal close of business of the Company 
on the ninetieth (90th) day after such resignation and/or removal.  

9.   Tax  Withholding  .  Unless  otherwise  provided  by  the  Committee  prior  to  the  vesting  of  Option,  the  Optionee  shall  satisfy  any 
federal, state, local or foreign employment or income taxes due upon the vesting of Option (or otherwise) by having the Company withhold from 
those  shares  of  Stock  that  the  Optionee  would  otherwise  be  entitled  to  receive,  a  number  of  shares  having  a  fair  market  value  equal  to  the 
minimum  statutory  amount  necessary  to  satisfy  the  Company’s  applicable  federal,  state,  local  and  foreign  income  and  employment  tax 
withholding obligations. Any such withholding shall be subject to the provisions of applicable law and to any conditions the Committee may 
determine  to  be  necessary  to  comply  with  Rule 16b-3  or  its  successors  under  the  Exchange  Act.  In  lieu  of,  and  subject  to,  the  above,  the 
Committee  may  also  permit the  Optionee  to satisfy  any  federal, state,  local,  or foreign  employment  or  income  taxes  due  upon  the  vesting  of 
Option (or otherwise) by (i) personal check or other cash equivalent acceptable to the Company, (ii) permitting the Optionee to execute a same 
day sale of Stock pursuant to procedures approved by the Company, or (iii) such other method as approved by the Committee, all in accordance 
with applicable Company policies and procedures and applicable law.  

10.  Nontransferability . The Option granted by this Agreement shall not be transferable by the Optionee or any other person claiming 

through the Optionee, either voluntarily or involuntarily, except by will or the laws of descent and distribution.  

11.  Nonstatutory Stock Option . The Option granted hereunder is a nonstatutory (non-qualified) stock option, and is not an “incentive 

stock option” pursuant to the Code.  

2 

   
   
   
   
   
   
   
  
12.   Stock  Certificates  .  Notwithstanding  anything  herein  to  the  contrary,  the  Company  shall  not  be  required  to  issue  or  deliver  any 
certificates evidencing shares of Stock pursuant to the exercise of the Option, unless and until the Committee has determined, with advice of 
counsel, that the issuance and delivery of such certificates is in compliance with all applicable laws, regulations of governmental authorities and, 
if  applicable,  the  requirements  of  any  exchange  or  quotation  system  on  which  the  shares  of  Stock  are  listed,  quoted  or  traded.  All  Stock 
certificates delivered pursuant to this Agreement are subject to any stop-transfer orders and other restrictions as the Committee deems necessary 
or advisable to comply with Federal, state, or foreign jurisdiction, securities or other laws, rules and regulations and the rules of any national 
securities exchange or automated quotation system on which the Stock is listed, quoted, or traded. The Committee may place legends on any 
Stock certificate to reference restrictions applicable to the Stock. In addition to the terms and conditions provided herein, the Board Directors 
may  require  that  the  Optionee  make  such  reasonable  covenants,  agreements,  and  representations  as  the  Board  of  Directors,  in  its  discretion, 
deems advisable in order to comply with any such laws, regulations, or requirements.  

13.  Change in Control . Notwithstanding any other provision herein to the contrary, upon a Change in Control, the entire Option shall 

automatically become immediately vested and/or exercisable and that all restrictions relating to the Option shall lapse.  

a.  “Change in Control” means any one or more of the following events:  

(i) The  date  that  any  one  person,  or  more  than  one  person  acting  as  a  group  (as  determined  in  accordance  with 
Treasury  Regulation Section 1.409A-3(i)(5)),  acquires  ownership  of  stock  of  the  Company  that,  together  with  stock  held  by  such  person  or 
group,  constitutes  more  than  50%  of  the  total  fair  market  value  or  total  voting  power  of  the  stock  of  the  Company.  This  paragraph  (i) only 
applies when there is a transfer of stock of the Company (or issuance of stock of the Company) and stock in the Company remains outstanding 
after the transaction;  

(ii) The  date  that  any  one  person,  or  more  than  one  person  acting  as  a  group  (as  determined  in  accordance  with 
Treasury  Regulation Section 1.409A-3(i)(5)),  acquires  (or  has  acquired  during  the  12-month  period  ending  on  the  date  of  the  most  recent 
acquisition by such person or persons) assets from the Company that have a total gross fair market value equal to or more than 40% of the total 
gross fair market value of all of the assets of the Company immediately prior to such acquisition or acquisitions. For this purpose, “gross fair 
market  value”  means  the  value  of the  assets  of  the  Company,  or  the  value of the  assets  being disposed  of,  determined  without regard  to  any 
liabilities associated with such assets; or  

(iii) The date that any person, or more than one person acting as a group (as determined in accordance with Treasury 
Regulation 1.409A-3(i)(5)),  acquires  (or  has  acquired  during  the  12-month  period  ending  on  the  most  recent  acquisition  by  such  person  or 
persons) ownership of stock of Company possessing 30% or more of the total voting power of the stock of Company.  

3 

   
   
   
   
   
   
   
  
The transfer of stock or assets of the Company in connection with a bankruptcy filing by or against the Company under Title 11 of the United 
States Code will not be considered to be a Change of Control for purposes of this Agreement. Additionally, a transaction shall not constitute a 
Change in Control if its sole purpose is to change the state of the Company’s incorporation or to create a holding company that will be owned in 
substantially the same proportions by the persons who held the Company’s securities immediately before such transaction.  

14.  Waiver and Modification . The provisions of this Agreement may not be waived or modified unless such waiver or modification is 

in writing and signed by a representative of the Committee.  

15.  Adjustments . In the event of any change in the outstanding shares of Stock by reason of a stock dividend or split, recapitalization, 
merger, consolidation, combination, exchange of shares, or other similar corporate change, the aggregate number of shares of Stock subject to 
the Option and its stated exercise price shall be adjusted appropriately by the Committee, whose determination shall be conclusive; provided, 
however, that fractional shares shall be rounded to the nearest whole share. Moreover, in the event of such transaction or event, the Committee, 
in its discretion, may provide in substitution for the Option such alternative consideration (including cash) as it, in good faith, may determine to 
be equitable under the circumstances and may require in connection therewith the surrender of the Option so replaced. Further, with respect to 
any Option that otherwise satisfies the requirements of the stock rights exception to Section 409A of the Code, any adjustment pursuant to this 
Section 15 shall be made consistent with the requirements of the final regulations promulgated pursuant to Section 409A of the Code.  

16.  Requirements of Law  

a.  Securities Act . The Company shall not be required to deliver any shares of Stock pursuant to the vesting of the Option if, 
in  the  opinion  of  counsel  for  the  Company,  such  issuance  would  violate  the  Securities  Act  of  1933  or  any  other  applicable  federal  or  state 
securities laws or regulations. The granting of the Option and the issuance of shares and/or cash under this Agreement shall be subject to all 
applicable laws, rules, and regulations, and to such approvals by any governmental agencies or national securities exchanges as may be required. 
The  Company  shall  be  under  no  obligation  to  register  pursuant  to  the  Securities  Act  of  1933,  as  amended,  any  of  the  shares  of  Stock  paid 
pursuant  to  the  Agreement.  If  the  shares  of  Stock  paid  pursuant  to  the  Agreement  may  in  certain  circumstances  be  exempt  from  registration 
pursuant to the Securities Act of 1933, as amended, the Company may restrict the transfer of such shares in such manner as it deems advisable to 
ensure the availability of any such exemption.  

b.   Securities  Law  Compliance  .  If  Optionee  is  obligated  to  file  reports  pursuant  to  Section 16  of  the  Exchange  Act, 
transactions pursuant  to this  Agreement are  intended to comply  with all  applicable  conditions of Rule 16b-3 or  its successors pursuant to  the 
Securities Exchange Act of 1934. Notwithstanding any other provision herein, the Committee may impose such conditions on the exercise of the 
Option as may be required to satisfy the requirements of Rule 16b-3 or its successors pursuant to the Securities Exchange Act of 1934. To the 
extent any provision herein or action by the Committee fails to so comply, it shall be void to the extent permitted by law and voidable as deemed 
advisable by the Committee.  

4 

   
   
   
   
   
   
   
  
c.   Restrictions  .  The  Committee  shall  impose  such  restrictions  on  the  Option  as  it  may  deem  advisable,  including  without 
limitation, restrictions under applicable federal securities law, under the requirements of any Stock exchange upon which the Stock is then listed 
and under any blue sky or state securities laws applicable to such Option.  

17.  Section 409A of the Code .  

a.  General Compliance . If this Agreement is subject to Section 409A of the Code, the Company intends (but cannot and does 
not guarantee) that this Agreement complies fully with and meets all of the requirements of Section 409A of the Code or an exception thereto. 
To the extent necessary to comply with Section 409A of the Code, this Agreement may be modified, replaced or terminated in the discretion of 
the  Committee.  Notwithstanding  any  provision  of  this  Agreement  to  the  contrary,  in  the  event  that  the  Committee  determines  that  this 
Agreement is or may become subject to Section 409A of the Code, the Company may adopt such amendments to this Agreement, without the 
consent of Optionee, or adopt other policies and procedures (including amendments, policies and procedures with retroactive effective dates), or 
take any other action that the Committee determines to be necessary or appropriate to either comply with Section 409A of the Code or to exclude 
or exempt this Agreement from the requirements of Section 409A of the Code.  

b.  Delay for Specified Employees . If, at the time of Optionee’s “separation of service” the Company has any Stock which is 
publicly traded on an established securities market or otherwise, and if the Optionee is considered to be a “specified employee” to the extent any 
payment or consideration under this Agreement is subject to the requirements of Section 409A of the Code and is payable upon the Optionee’s 
“separation from service,” such payment shall not commence prior to the first business day following the date which is six (6) months after the 
Optionee’s “separation from service” (or if earlier than the end of the six (6) month period, the date of the Optionee’s death). Any amounts that 
would have been distributed during such six (6) month period will be distributed on the day following the expiration of the six (6) month period.  

c.   Prohibition  on  Acceleration  or  Deferral  .  Under  no  circumstances  may  the  time  or  schedule  of  any  payment  for  any 
amount under this Agreement that is subject to the requirements of Section 409A of the Code be accelerated or subject to further deferral except 
as otherwise permitted or required pursuant to regulations and other guidance issued pursuant to Section 409A of the Code. If the Company fails 
to  make  any  payment  pursuant  to  the  payment  provisions  applicable  to  this  Agreement  that  is  subject  to  Section 409A  of  the  Code,  either 
intentionally or unintentionally, within the time period specified in such provisions, but the payment is made within the same calendar year, such 
payment  will  be  treated as made within  the  time  period specified in  the provisions.  In  addition, in  the  event  of  a dispute  with respect  to  any 
payment, such payment may be delayed in accordance with the regulations and other guidance issued pursuant to Section 409A of the Code.  

5 

   
   
   
   
   
   
  
18.  Voting and Other Shareholder Related Rights . The Optionee will have no voting rights or any other rights as a shareholder of the 

Company with respect to any Option until exercised by the Optionee.  

19.  Governing Law . This Agreement shall be interpreted and administered under the laws of the State of Nevada.  

20.  Amendments . This Agreement may be amended only by a written agreement executed by the Company and the Optionee.  

IN WITNESS WHEREOF, the Company has caused this Agreement to be executed by its duly authorized representative and Optionee 

has signed this Agreement, and this Agreement shall be effective as of the day and year first written above.  

12/18/14 
Date 

Cryoport, Inc. 

By: 
Name:   Robert Stefanovich 
Title:  Chief Financial Officer 

6 

   
   
   
   
   
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
CryoPort Systems, Inc.  

CRYOPORT, INC.  
Subsidiaries of Registrant  

EXHIBIT 21 

   
   
  
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM  

We consent to the incorporation by reference in the Registration Statement Nos. 333-159899, 333-166327, 333-177168, 333-184543 and 333-
197437 on Form S-8 of our report dated May 19, 2015 (which includes an explanatory paragraph regarding Cryoport, Inc.’s ability to continue 
as  a  going  concern),  with  respect  to  the  consolidated financial  statements  of  Cryoport,  Inc. included  in  this  Annual Report  on Form  10-K  of 
Cryoport, Inc. for the years ended March 31, 2015 and 2014.  

EXHIBIT 23.1 

/s/ KMJ Corbin & Company LLP  

Costa Mesa, California  
May 19, 2015  

   
    
   
   
   
   
   
   
   
  
CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER  

EXHIBIT 31.1 

I, Jerrell W. Shelton, certify that:  

1. 

2. 

3. 

4. 

I have reviewed this Annual Report on Form 10-K of Cryoport, Inc.; 

Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to 
make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period 
covered by this report; 

Based  on  my  knowledge,  the  financial  statements,  and  other  financial  information  included  in  this  report,  fairly  present  in  all  material 
respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report; 

The  registrant’s  other  certifying  officer  and  I  are  responsible  for  establishing  and  maintaining  disclosure  controls  and  procedures  (as 
defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 
13a-15(f) and 15d-15(f)) for the registrant and have: 

a)  Designed  such  disclosure  controls  and  procedures,  or  caused  such  disclosure  controls  and  procedures  to  be  designed  under  our 
supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to 
us by others within those entities, particularly during the period in which this report is being prepared; 

b)  Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under 
our  supervision,  to  provide  reasonable  assurance  regarding  the  reliability  of  financial  reporting  and  the  preparation  of  financial 
statements for external purposes in accordance with generally accepted accounting principles; 

c) 

Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about 
the  effectiveness  of  the  disclosure  controls  and  procedures,  as  of  the  end  of  the  period  covered  by  this  report  based  on  such 
evaluation; and 

d)  Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s 
most  recent  fiscal  quarter  (the  registrant’s  fourth  fiscal  quarter  in  the  case  of  an  annual  report)  that  has  materially  affected,  or  is 
reasonably likely to materially affect, the registrant’s internal control over financial reporting; and 

5. 

The  registrant’s  other  certifying  officer  and  I  have  disclosed,  based  on  our  most  recent  evaluation  of  internal  control  over  financial 
reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent 
functions): 

a)  All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are 
reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and 

b)  Any  fraud,  whether  or  not  material,  that  involves  management  or  other  employees  who  have  a  significant  role  in  the  registrant’s 

internal control over financial reporting. 

Date: May 19, 2015  

/s/ JERRELL W. SHELTON 
JERRELL W. SHELTON 
Chief Executive Officer and Director 
(Principal Executive Officer) 

  
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
CERTIFICATION OF PRINCIPAL FINANCIAL OFFICER  

EXHIBIT 31.2 

I, Robert S. Stefanovich, certify that:  

1. 

2. 

3. 

4. 

I have reviewed this Annual Report on Form 10-K of Cryoport, Inc.; 

Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to 
make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period 
covered by this report; 

Based  on  my  knowledge,  the  financial  statements,  and  other  financial  information  included  in  this  report,  fairly  present  in  all  material 
respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report; 

The  registrant’s  other  certifying  officer  and  I  are  responsible  for  establishing  and  maintaining  disclosure  controls  and  procedures  (as 
defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 
13a-15(f) and 15d-15(f)) for the registrant and have: 

a)  Designed  such  disclosure  controls  and  procedures,  or  caused  such  disclosure  controls  and  procedures  to  be  designed  under  our 
supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to 
us by others within those entities, particularly during the period in which this report is being prepared; 

b)  Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under 
our  supervision,  to  provide  reasonable  assurance  regarding  the  reliability  of  financial  reporting  and  the  preparation  of  financial 
statements for external purposes in accordance with generally accepted accounting principles; 

c) 

Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about 
the  effectiveness  of  the  disclosure  controls  and  procedures,  as  of  the  end  of  the  period  covered  by  this  report  based  on  such 
evaluation; and 

d)  Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s 
most  recent  fiscal  quarter  (the  registrant’s  fourth  fiscal  quarter  in  the  case  of  an  annual  report)  that  has  materially  affected,  or  is 
reasonably likely to materially affect, the registrant’s internal control over financial reporting; and 

5. 

The  registrant’s  other  certifying  officer  and  I  have  disclosed,  based  on  our  most  recent  evaluation  of  internal  control  over  financial 
reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent 
functions): 

a)  All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are 
reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and 

b)  Any  fraud,  whether  or  not  material,  that  involves  management  or  other  employees  who  have  a  significant  role  in  the  registrant’s 

internal control over financial reporting. 

Date: May 19, 2015  

/s/ ROBERT S. STEFANOVICH 
Robert S. Stefanovich 
Chief Financial Officer 
(Principal Financial Officer) 

  
   
   
   
   
   
   
   
   
   
   
   
   
   
    
   
   
  
  
  
  
  
CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER  

Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, the undersigned officer of Cryoport, 
Inc. (the “Company”), hereby certifies, to such officer’s knowledge, that:  

(i) the accompanying Annual Report on Form 10-K of the Company for the year ended March 31, 2015 (the “Report”) fully complies with 

the requirements of Section 13(a) or Section 15(d), as applicable, of the Securities Exchange Act of 1934, as amended; and  

(ii) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the 

EXHIBIT 32.1 

Company.  

Date: May 19, 2015  

This certification accompanies this Report pursuant to Rule 13a-14(b) or Rule 15d-14(b) under the Securities Exchange Act of 1934, as 
amended, and 18 U.S.C. Section 1350 and shall not be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act 
of 1934, as amended.  

/s/ JERRELL W. SHELTON 
Jerrell W. Shelton 
Chief Executive Officer and Director 

  
  
   
   
   
   
   
   
   
   
  
  
  
  
CERTIFICATION OF PRINCIPAL FINANCIAL OFFICER  

EXHIBIT 32.2 

Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, the undersigned officer of Cryoport, 
Inc. (the “Company”), hereby certifies, to such officer’s knowledge, that:  

(i) the accompanying Annual Report on Form 10-K of the Company for the year ended March 31, 2015 (the “Report”) fully complies with 

the requirements of Section 13(a) or Section 15(d), as applicable, of the Securities Exchange Act of 1934, as amended; and  

(ii) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the 

Company.  

Date: May 19, 2015  

This certification accompanies this Report pursuant to Rule 13a-14(b) or Rule 15d-14(b) under the Securities Exchange Act of 1934, as 
amended, and 18 U.S.C. Section 1350 and shall not be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act 
of 1934, as amended.  

/s/ ROBERT S. STEFANOVICH 
Robert S. Stefanovich 
Chief Financial Officer