Eli Lilly and Company Annual Report 2003

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FY2003 Annual Report · Eli Lilly and Company

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2003

Answers for Shareholders

Eli Lilly and Company Annual Report, Notice of Annual Meeting, and Proxy Statement

YEAR IN REVIEW

1 Financial Highlights
2 Letter to Shareholders
6

Innovation From the Lilly Pipeline

FINANCIALS

8 Review of Operations
13 Consolidated Statements of Income
15 Consolidated Balance Sheets
22 Consolidated Statements of Cash Flows
23 Consolidated Statement of Comprehensive Income
24 Segment Information
25 Selected Quarterly Data
26 Selected Financial Data
27 Notes to Consolidated Financial Statements
43 Responsibility for Financial Statements
44 Report of Independent Auditors

PROXY STATEMENT

45 Notice of 2004 Annual Meeting and Proxy Statement
47 General Information
52 Board of Directors
63 Directors and Corporate Governance Committee Matters
64 Audit Committee Matters
66 Executive Compensation
72 Performance Graph
73 Ownership of Company Stock
75
81 Other Matters
82 Appendices

Items of Business To Be Acted Upon at the Meeting

CORPORATE INFORMATION

92 Senior Management
93 Corporate Information
94 Trademarks
95 Annual Meeting Admission Ticket and Parking Information

2003 FINANCIAL HIGHLIGHTS

Eli Lilly and Company and Subsidiaries
(Dollars in millions, except per-share data)

Year Ended December 31

2003

2002

Change %

Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$12,582.5

$11,077.5

Research and development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2,350.2

2,149.3

Research and development as a percent of sales . . . . . . . . . . . . . . . .

18.7%

19.4%

Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 2,560.8

$ 2,707.9

Earnings per share—basic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Earnings per share—diluted. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Dividends paid per share. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2.38

2.37

1.34

2.51

2.50

1.24

Capital expenditures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

1,706.6

1,130.9

(5)

Sidney Taurel, chairman of the board, president, and chief
executive ofﬁ cer, spoke to employees worldwide via broadcast
television in January 2004. Their success in overcoming the
unprecedented challenges of the past couple of years puts the
company on the threshold of historic opportunity, he said.

“I am honored to lead an organization of talented and committed
people who are making a real difference every day in the lives
of millions of people. And now, as we are rolling out the most
impressive array of new medicines in the pharmaceutical
industry, we are poised to fulﬁ ll our aspirations and make a
difference to millions more. It’s up to us to make it happen.
I’m sure we can. And I know we will.”

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TO OUR SHAREHOLDERS

The changes you see in this year’s annual report are a
small part of a much broader effort to focus on the needs
of our external stakeholders and, at the same time, to be
more productive with every dollar we spend. We saw an
opportunity to free up some resources by refocusing on
what our shareholders really want from this document.
The favorable reaction we’ve had to the question-and-
answer segments in recent reports tells us that what you
want is simply clear, concise ﬁ nancial information and
straightforward answers to your questions about how the
company is doing and where it is heading. I will do my
best to provide those answers in this and future reports.
But ﬁ rst, as context, let me offer a brief overview of our
performance in 2003.

In terms of ﬁ nancial results, we delivered strong sales
growth of 14 percent for the year. Reﬂ ecting heavy invest-
ment to support an unprecedented ﬂ ow of innovation,
net income and diluted earnings per share both decreased
5 percent. However, excluding unusual charges and a one-
time gain on an out-licensing transaction, as described on
page 8, our earnings would have increased slightly.

In fact, we’re coming off a year of strong operational

performance. We met important milestones in all key
dimensions of our strategy in 2003, reﬂ ecting a sustained
and successful effort to build our capabilities. For a num-
ber of years, we’ve been investing in the tools, technolo-
gies, processes, and people that we believe are essential
to winning with our innovation-centered strategy. As a
result, we are a much stronger company today than we
were even a few years ago.

Without question, the success of our research and
development pipeline was the big story of the year. Within
the space of 15 months, Lilly has launched ﬁ ve new prod-
ucts, beginning with Forteo® for osteoporosis and Strattera®
for ADHD, followed by Cialis® for erectile dysfunction,
Symbyax™ for bipolar depression, and most recently by

our new cancer agent, Alimta®. Later this year, we expect
to add Cymbalta™ for depression and duloxetine for stress
urinary incontinence. With those launches, we will have
more than doubled our portfolio of growth products in a
two-year span—a feat unprecedented in the industry. Also,
continuing our pattern for the last decade, ﬁ ve of these new
products are ﬁ rst-in-class drugs, while two represent best-in-
class products. This outpouring runs very much against the
trend of the times. Many of our peers have been experienc-
ing a decrease in R&D productivity.

Lilly’s current ﬂ ood of industry-leading launches is
the result of several actions taken over the last decade to
improve productivity and create leading-edge capabilities
in R&D. These include, ﬁ rst and foremost, a ﬁ nancial
commitment to R&D that is at the top of the industry
relative to sales. In addition, we have recruited top talent
from academia as well as from industry, including an un-
usually large number of research physicians. In another
important restructuring, we have been capitalizing on
our unique and highly productive biotechnology assets
and integrating them with our small-molecule research
expertise. The creative output of all our talented people is
optimized by a rigorous portfolio management process.
As we move forward, we continue to focus on

reducing the number of compounds that fail in late-stage
development. More and more, our researchers are build-
ing and using a knowledge base of biomarkers—physi-
ological clues from early-stage research—that allow us to
better predict which drug candidates are most likely to
succeed at later phases of testing. Moreover, we are invest-
ing in brand new tools and technologies. For example, our
acquisition of AME—Applied Molecular Evolution—will
afford us access to cutting-edge technologies for creating
custom-designed biotechnology drugs. In addition, one of
our e-business ventures, InnoCentive, has created a global
online forum for posting unsolved technical problems

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Nine Key Growth Products
Collectively Delivered 24 Percent
Increase in Net Sales
($ millions; percentages represent
changes from 2002)

%
6
1
+

8
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+

Established
Growth Products

Newly Launched
Growth Products

The company’s established key growth
products—Zyprexa, Humalog,
Gemzar, Evista, and Actos—gener-
ated $1.1 billion of incremental net
sales and $7.7 billion of total
net sales in 2003. In addition, our
newly launched growth products—
Strattera, Cialis, Forteo, and Xigris—
generated $670 million of net sales
in 2003. Combined, all our key growth
products grew 24 percent for the
year.

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and securing solutions from scientists around the world.
It’s a groundbreaking application of one of our guiding
concepts—that of doing “research without walls.”

At the same time, we’ve greatly strengthened our
sales and marketing functions to capture the full value of
our innovative products. For example, in response to the
tremendous expansion of our product portfolio, we will
have nearly doubled the size of our U.S. selling presence
(including partners) between 1999 and 2004. By the end
of this year, our sales force outside the U.S. will be about
50 percent larger than it was four years ago. However, our
main focus has not been on getting bigger but on becom-
ing more responsive to our customers and better able to
address their needs.

In addition to ﬁ ne-tuning our skills in the traditional

marketing and selling efforts directed at providers and
private payers, we’ve enhanced our ability to compete
in consumer marketing and created the industry’s ﬁ rst
business-to-government sales organization. We’re using
both new and traditional communications technology to
build vital two-way relationships with our customers. For
instance, launches of both Forteo and Strattera beneﬁ ted
greatly from feedback coming through our U.S. call cen-
ter—a facility that now handles some 3,500 inquiries each
week. In both cases, we were able to learn about special
needs and concerns from patients or caregivers and bring
our medical expertise to bear on offering effective answers.
Four consecutive quarters of double-digit sales growth

from our established brands are powerful evidence of
the value of what we’ve built in this part of the business.
Gemzar® and Humalog® both became billion-dollar
products in 2003, and Evista® is “knocking on the door” at
over $920 million. Zyprexa sales increased by 16 percent,
to $4.3 billion, with especially strong growth coming from
outside the U.S. Finally, the outstanding launches of our
new products—Strattera, Forteo, and Cialis—combined to
deliver more than $500 million in revenues for the year.
We’ve also done a great deal of work in manufactur-
ing to build world-class manufacturing capabilities and
address quality issues in this area. We’ve made signiﬁ cant

investments in modernizing our facilities, as well as creat-
ing new capacity for our growth products. We’ve hired
and transferred into manufacturing and quality hundreds
of experienced employees with high levels of expertise
and undertaken a massive training and development
program. We’ve also been working to streamline and
simplify our processes in these operations.

We made very signiﬁ cant progress in 2003 as illus-
trated by the FDA’s decision to consider the company’s
injectable and dry product plants in Indianapolis to be in
a state of compliance with current Good Manufacturing
Practices. This subsequently led to a successful preapprov-
al inspection for Zyprexa® IntraMuscular at Indianapolis.
Based on this outcome, the FDA has indicated that it
does not currently believe a preapproval inspection for
Cymbalta will be necessary, although such an inspection
remains at the discretion of the FDA. In addition, we’ve
had two successful preapproval inspections for Cialis and
Alimta. We are pleased with the progress we’ve made
thus far and are committed not only to sustain it but to
make Lilly the benchmark for quality within the industry.
Finally, partnering has become an integral skill in all

phases of our business. Our partnerships with Centocor
for ReoPro®, with Takeda for Actos®, and now with ICOS
for Cialis have all extended beyond product development
and into the arena of sales and marketing. As we look
ahead, we will partner with Quintiles to market Cymbalta
in the U.S. and Boehringer Ingelheim for Cymbalta
outside the U.S. and duloxetine SUI worldwide, excluding
Japan. Recognizing the growing contribution of partner-
ing all along the value chain, we have elevated it to a key
role in our strategy and created the industry’s ﬁ rst ofﬁ ce
of alliance management to keep learning and improving
in this vital dimension. Ultimately, partnering enhances
our ability to keep winning as a mid-sized competitor in
a world of behemoths. It serves as a tremendous “force
multiplier” for all the other capabilities we have built—a
way of adding strength without adding size.

Overall, I believe the people of Lilly have success-
fully met each of the key challenges that we have faced.
In terms of our operational ﬁ tness, we are now well
positioned to deliver on our promise of strong growth.
Looking ahead, I believe the next set of challenges is not
internal or even competitive issues. Rather they arise in
the arena of public policy that increasingly deﬁ nes the
limits of our business environment.

As populations in the developed world grow older
and health care expenditures grow larger, the focus on
our industry as a cost driver is intensifying. It doesn’t
matter whether this pressure is fair or reasonable—it is
a fact. And while we must, as an industry, step up our ef-
forts to make our case for the incredible value we deliver
to society, we must also be prepared to contribute solu-
tions to the growing problem of affordability. To that end,
I am challenging the organization to focus on improving
productivity in all phases of the business. Doing more

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with less—that is the best way to generate the innovation
patients need at prices payers demand and still deliver the
results our investors require.

Questions and Answers

Q: How can Lilly do justice to so many new products all
at once? And, with so many launches, can you afford to
grow earnings in 2004?

A: We can both capitalize on the potential of our
product portfolio and produce income growth in ’04,
largely because we have already made many of the
necessary investments in the previous couple of years and
because Strattera and Forteo are already paying off on the
bottom line. We have been preparing ourselves for this
challenge for quite some time, as I indicated above, by in-
creasing our capacity in both marketing and sales, as well
as revamping the whole marketing research, marketing
planning, and selling processes. We have therefore put in
place several sales forces that will each have its own set
of priorities so as to optimize the potential of our whole
product line. This year, we are investing aggressively to
market Cialis in the U.S. and will have additional new
expenditures when we launch Cymbalta and duloxetine
SUI, but, for the most part, the infrastructure investments
needed to support these launches are already in our base.

Q: Certain key ﬁ nancial ratios such as return on assets
(ROA) and return on shareholders’ equity (ROE) have
been declining in recent years. What is the cause of this
trend—and what are the prospects for the future?
A: The decline of our ROA and ROE was largely
triggered by the rapid decline in the U.S. sales of Prozac®,
our top-selling product at that time, after it faced generic
competition in August 2001. At the very time we faced
the Prozac downturn (and as a key part of our effort to
overcome it), we needed to make heavy investments in our
innovation-driven strategy. Very importantly, we invested
aggressively in a number of high-potential drug candidates
to accelerate their launches and subsequent uptake and
thereby expand our growth opportunities. As we increased
the sales-and-marketing support for our growing product
line, we also needed to make investments in manufacturing,
not only to address the quality issues identiﬁ ed by the FDA
but also to expand our global production capacity. And,
of course, we continued to plow the highest percentage of
sales among our peers—some 19 percent on average—back
into the R&D programs on which our future depends.

Consequently, the decreases in ROA and ROE we
have recently experienced reﬂ ect our investments in the
future of the company. We believe that the series of re-
cent new-product launches that is effectively doubling the
size of our product line will position us to generate strong
growth in sales and earnings and reverse the decline in
those key ﬁ nancial ratios and improve them over the next
several years.

Q: Lilly’s stock price has been largely unchanged since
1998. Can you comment?

A: While we share the frustration our shareholders
feel with the sidewise movement of our share price, it’s
important to put the stock’s performance in perspective. In
a down market for our entire sector, Lilly has maintained
its value better than its peers. If you look at the U.S.-based
ﬁ rms that are “pure play” pharmaceutical companies,
Lilly represented 12 percent of the market capitalization
of this group at the end of 1998. At the end of 2003, Lilly
represented 13.4 percent of the market capitalization of
the same group. During the interval, we never went below
10.5 percent, despite the huge hit of losing the Prozac pat-
ent in the U.S. We believe we are well positioned for future
growth and, judging by our strong PE multiple through
2003, many investors share these expectations.

Q: Zyprexa is facing many challenges. What reassurance
can you give shareholders about the future of this key
product?

A: Zyprexa has been the most successful product in
the history of neuroscience, and it continues to grow, as
I’ve indicated. In the U.S., where Zyprexa is the leader
among antipsychotics, it has been a target of attacks from
competitors. Those attacks have focused particularly on
the product’s propensity to provoke weight gain in some
patients and on allegations of a link with diabetes. Last
year, following an exhaustive review of all the available
data, the FDA concluded that the incidence of diabetes
was higher among patients with schizophrenia or bipolar
disorder, in general, and that there appears to be a higher
prevalence of diabetes among patients being treated
with atypical agents compared with older antipsychotics.
However, the agency was unable to differentiate among
the risk proﬁ les of the various atypical antipsychotics on
this issue. Consequently, the FDA recommended a label
change for the entire class. The debate continues. How-
ever, we believe the weight of scientiﬁ c evidence supports
the FDA’s approach, and that, over time, it should prevail
and serve to level the playing ﬁ eld.

Although the competition will continue to be stiff,
we see abundant new opportunities ahead for Zyprexa.
In 2004, we will capitalize on the approval and launch of
Symbyax—the combination of Zyprexa and Prozac—as
the ﬁ rst product approved for bipolar depression as
well as the recent approval for bipolar maintenance to
position Zyprexa as a foundational treatment for bipolar
disease. In addition, the launch of Zyprexa rapid-acting
intramuscular will address a need in the agitated phase
of both schizophrenia and bipolar disease. Moreover,
we are just beginning to tap the true global potential
of Zyprexa. Outside the United States, the penetration
of atypical antipsychotics is still limited. But as more
and more physicians around the world have come to
recognize its outstanding efﬁ cacy and side-effect proﬁ le,
Zyprexa is growing very fast.

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Q: Lilly’s recent success in R&D has run counter to the
current disappointing trend in the industry. Can you keep
it up?

A: Generally speaking, yes. The outpouring of new
Lilly products is not the result of good luck but of great
strategic implementation. This effort is still a work in
progress, but as evidence that we’re on the right track, I
would point to our robust pipeline. We have several ex-
tremely promising drug candidates moving in or toward
late-stage development. I would highlight three to watch
in the next wave: exenatide, a potential ﬁ rst-in-class agent
for type 2 diabetes that we’re developing with Amylin;
ruboxistaurin, our PKC beta inhibitor, that treats the type
of blood vessel damage associated with diabetes that
commonly leads to visual impairment or serious nerve
damage; and CS-747 for acute coronary syndrome and
stroke that we’re developing with Sankyo. All these have
the potential to be very big drugs.

Q: What impact will the new Medicare prescription drug
beneﬁ t have on Lilly’s ﬁ nancial outlook?

tation has also been damaged by news reports of incidents
of unethical or overly aggressive commercial conduct—
touching everything from advertising and promotional
practices to the design, conduct, and communication of
clinical trials. We have reﬁ ned and reinforced long-stand-
ing policies that embrace high standards of conduct in our
interactions with all key constituencies, whether patients,
physicians, employers, or government ofﬁ cials. We have
spelled out for our people the kind of ethical behavior
we expect in promoting our products, advertising to
consumers, or designing, conducting, and communicating
the results of clinical trials. And we have put in place a
comprehensive compliance program designed to ensure
adherence to these guidelines. Finally, along with other
Lilly senior executives, I am personally committed to an
ongoing program of direct dialogue with a broad spectrum
of opinion leaders to promote a greater understanding
of what our industry contributes and how it really works
within our health care system. I invite you all to read what
we have to say by visiting our website at www.lilly.com.

A: First, a new Medicare prescription drug beneﬁ t

Management Changes

will allow those seniors who have the most need for
them—those with low incomes or high drug costs—to
have access to pharmaceutical products. This will almost
certainly increase sales volume. However, as this beneﬁ t
will be administered through the private sector, we expect
to see many of the cost-containment tools used by man-
aged care organizations. Thus, we generally anticipate
that volume increases generated as a result of broader
access by patients would be offset by more discounting.
However, the outlook may change. The prescription drug
beneﬁ t will not be implemented until 2006, and, in the
meantime, is still the subject of political debate.

Q: What are you doing at Lilly to address the negative
public image of the industry?

A: The negative public image of the industry stems
from a number of causes. The root of it is the fact that,
while pharmaceuticals represent only 10 percent of
health care costs, they represent a much larger percentage
of out-of-pocket costs for patients. Therefore, it is very
important to address the issue of access and coverage. In
the U.S., we have worked with our colleagues in the indus-
try to encourage a Medicare drug beneﬁ t, which can be
the foundation of a solution. But we did not wait for this
legislation to start helping seniors. We launched our own
“LillyAnswers” program, which makes any Lilly product
available to low income seniors for just $12 a month. In
addition, our “Lilly Cares” program offers our medicines
free to needy patients, regardless of age, who could not
otherwise afford them. Outside the U.S., we have created
a program with the World Health Organization and other
partners to address the growing worldwide problem of
multiple-drug-resistant tuberculosis.

Beyond the cost and access issues, the industry’s repu-

Finally, I want to note some signiﬁ cant changes in our
management team since I last wrote to you. In June
2003, August Watanabe, M.D., retired from the board
and from his position as executive vice president, science
and technology. It is impossible in this brief space to do
justice to Dr. Watanabe’s extraordinary contributions, but
in essence he took our research organization from good to
great. Succeeding him as executive vice president, science
and technology, is Steven Paul, M.D., formerly group vice
president of therapeutic area discovery research and clini-
cal investigation for Lilly Research Laboratories.

In March 2004, Gerhard Mayr retires as executive
vice president, pharmaceutical operations. Capping a
career of contributions to Lilly operations in many parts
of the world, in the past ﬁ ve years he has led Lilly’s global
sales and marketing operations, spearheading our sales
growth and helping transform Lilly into an organization
that can compete with the best. John Lechleiter, Ph.D.,
will become executive vice president for pharmaceutical
operations, assuming Mr. Mayr’s former role as well as
maintaining his previous responsibilities for pharmaceuti-
cal products and corporate development.

Finally, in 2003, we were delighted to welcome a new

member of our board of directors, Sir John Rose, chief
executive of Rolls-Royce, plc. Sir John’s deep experience
as a global business leader will further broaden the
international perspective of our board.

For the Board of Directors,

Sidney Taurel
Chairman of the Board, President, and Chief Executive Ofﬁ cer

INNOVATION FROM THE LILLY PIPELINE

Major Marketed Products

2004

Alimta®

for malignant pleural mesothelioma

Symbyax™

for bipolar depression

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Cialis®

for erectile dysfunction
(developed and marketed in joint venture with ICOS Corporation)

Strattera®

for attention-deﬁ cit hyperactivity disorder in children, adolescents, and adults

2002

Forteo®

For treatment of both men and postmenopausal women with osteoporosis who
are at high risk for fracture

2001

Xigris®

for adult severe sepsis patients at high risk of death

1999

Actos®

for type 2 diabetes
(marketed with Takeda Chemical Industries, Ltd.)

1998

Evista®

for prevention of osteoporosis in women past menopause
for treatment of osteoporosis in women past menopause (1999)

1996

Zyprexa®

for schizophrenia
for acute bipolar mania (2000)
for schizophrenia maintenance (2001)
as combination therapy with lithium or valproate for acute bipolar mania (2003)
for bipolar maintenance (2004)

Humalog®

for treatment of type 1 and type 2 diabetes

1995

Gemzar®

for pancreatic cancer
for non-small-cell lung cancer (1998)
for bladder cancer (Europe) (2000)
for breast cancer (Europe) (2003)

ReoPro®

for prevention of cardiac ischemic complications as an adjunct to percutaneous
coronary intervention (i.e., angioplasty)
(developed by Centocor, marketed by Lilly)

1987

Humatrope®

for growth failure caused by pediatric growth hormone deﬁ ciency
for replacement therapy for adult growth hormone deﬁ ciency (1996)
for short stature caused by Turner syndrome (1997)
for idiopathic short stature (2003)

1982

Humulin®

for type 1 and type 2 diabetes

New Drug Applications Declared Approvable by the U.S. Food and Drug Administration

Cymbalta™

Duloxetine

for major depressive disorder
(codeveloping with Boehringer Ingelheim in major markets, excluding
the U.S. and Japan)
(copromoting with Quintiles Transnational Corp. in the U.S.)

for women with symptoms of stress urinary incontinence
(codeveloping with Boehringer Ingelheim in major markets, excluding Japan)

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Drug candidates in late-stage investigation

Exenatide

for type 2 diabetes
(codeveloping with Amylin Pharmaceuticals, Inc.)

Ruboxistaurin

for diabetic microvascular complications

Arzoxifene

for the prevention and treatment of osteoporosis and breast cancer risk reduction

PPAR modulator

for improvement of insulin sensitivity and lipid metabolism
(developed out of a partnership with Ligand Pharmaceuticals)

Selected drug candidates in mid-stage investigation

CS747-LY640315

Pulmonary insulin

for acute coronary syndrome and stroke
(codeveloping with Sankyo Co., Ltd.)

for noninjectable delivery of insulin
(codeveloping with Alkermes, Inc.)

Enzastaurin

for non-Hodgkin’s lymphoma and other cancers

PPAR alpha agonist

for prevention of atherosclerosis
(developed out of a partnership with Ligand Pharmaceuticals)

Factor Xa inhibitor

for thrombotic disorders
(arose from a collaboration with Tularik Inc.)

All information as of February 25, 2004. The search for new drugs is risky and uncertain, and there are no guarantees. Remaining scientiﬁ c and regulatory
hurdles may cause a late-stage compound to be delayed or even fail to reach the market at all.

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REVIEW OF OPERATIONS

EXECUTIVE OVERVIEW

This section provides an overview of our ﬁ nancial re-
sults, product launches and late-stage product pipeline
developments, progress in improving our manufacturing
operations, expected acquisition of Applied Molecular
Evolution, Inc. (AME), in 2004, and legislative-related
activities affecting the pharmaceutical industry.

Financial Summary

Net income was $2.56 billion, or $2.37 per share, in
2003 and $2.71 billion, or $2.50 per share, in 2002,
decreases of 5 percent. We achieved strong worldwide
sales growth of 14 percent, to $12.58 billion; however,
in order to position ourselves for sustained growth in
an increasingly competitive environment, we chose to
signiﬁ cantly increase our investments in a number of
areas. To ensure the successful launches of our new
products discussed below, we substantially increased
our sales and marketing efforts. In addition, we made
substantial investments in our manufacturing opera-
tions and research and development activities. These
reinvestments into the business, together with lower
net other income, negatively affected earnings in 2003.
In addition, comparisons between 2003 and 2002 are
inﬂ uenced by the impact of the following items that are
reﬂ ected in the operating results (see Notes 3 and 4
to the consolidated ﬁ nancial statements for additional
information):

2003
• We streamlined our infrastructure in the ﬁ rst quarter

of 2003, resulting in severance-related and other
charges of $52.5 million (pretax), which decreased
earnings per share by $.03 in that quarter.

• We recognized asset impairments, primarily relating to
manufacturing assets in the U.S., totaling $114.6 million
(pretax) in the ﬁ rst quarter and $28.3 million (pretax)
in the fourth quarter, which decreased earnings per
share by approximately $.07 and $.02 in the ﬁ rst and
fourth quarters of 2003, respectively.

• Separately, we recognized asset impairments and
other charges of $186.8 million (pretax) in the ﬁ rst
quarter of 2003 related primarily to our common
stock ownership and loan agreements with Isis
Pharmaceuticals, Inc. (Isis), which decreased earnings
per share by $.13 in the ﬁ rst quarter of 2003.

• In the fourth quarter of 2003, we recorded a gain of
$65.0 million (pretax) related to the sale of patent
rights to dapoxetine for development in the ﬁ eld of
genitourinary disorders to PPD, Inc., which increased
earnings per share by $.04 in that quarter.

2002
• In the third quarter of 2002, we recognized a charge of
$84.0 million (pretax) for acquired in-process research
and development related to a collaboration arrangement
with Amylin Pharmaceuticals, Inc. (Amylin), to jointly
develop and commercialize exenatide, a potential new
treatment for type 2 diabetes, which decreased earnings
per share by approximately $.05 in that quarter.

Recent Product Launches and Late-Stage Product
Pipeline Developments

Our long-term success depends, to a great extent, on
our ability to continue to discover and develop innovative
pharmaceutical products and acquire or collaborate on
compounds currently in development by other biotechnol-
ogy or pharmaceutical companies. We have achieved a
number of successes with recent product launches and
late-stage pipeline developments, including:
• Strattera, the ﬁ rst treatment approved by the U.S. Food

and Drug Administration (FDA) for attention-deﬁ cit
hyperactivity disorder (ADHD) that is not a stimulant,
was ofﬁ cially launched in January 2003. We completed
the European submission for Strattera in the third
quarter of 2003.

• Forteo, a treatment for osteoporosis in postmenopausal
women and to increase bone mass in men with primary
osteoporosis, was ofﬁ cially launched in December 2002.
We received an approval in Europe during June of 2003.
• Cialis, a new treatment for male erectile dysfunction,
was launched by us and ICOS Corporation (ICOS) in
several key international markets during 2003 and
launched in the U.S. in early December 2003.

• Symbyax was launched in January 2004. Symbyax, a
combination of olanzapine (the active ingredient in
Zyprexa) and ﬂ uoxetine (the active ingredient in Prozac)
is the ﬁ rst FDA-approved medication for bipolar
depression, a notoriously difﬁ cult-to-treat condition
that afﬂ icts millions of Americans.

• Alimta, a treatment for malignant pleural mesothel-
ioma, was approved by the FDA in February 2004. In
addition, we have submitted Alimta for approval for
second-line non-small-cell lung cancer (NSCLC) in the
U.S. and malignant pleural mesothelioma and second-
line NSCLC in Europe.

• Cymbalta, a treatment for depression, received an
approvable letter from the FDA in the fall of 2003.
The FDA recently indicated that it does not currently
believe a preapproval inspection for Cymbalta will be
necessary. However, a preapproval inspection remains
at the discretion of the FDA. We have submitted our
complete response to the approvable letter and our
best estimate for U.S. approval and launch is the
summer of 2004.

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• Duloxetine for the treatment of stress urinary inconti-
nence received an approvable letter from the FDA in
the fall of 2003. Final FDA approval is contingent upon
successful completion of additional acute preclinical
and clinical pharmacology, label negotiations, and
preapproval inspection. We currently anticipate
approval in Europe in 2004 and U.S. approval in late
2004 or the ﬁ rst half of 2005.

Nine Key Growth Products
Accounted for 66 Percent of
2003 Sales ($ millions)

Combined net sales of the com-
pany’s key growth products—
Zyprexa, Humalog, Gemzar,
Evista, Actos, Strattera, Cialis,
Forteo, and Xigris—increased by
24 percent over 2002, repre-
senting $8.3 billion, or 66 percent
of total net sales, compared with
$6.7 billion, or 61 percent in 2002.

Prozac/Sarafem/Prozac Weekly

Other

Newly Launched Growth Products

(Strattera, Cialis, Forteo, and Xigris)

Established Growth Products (Zyprexa,

Humalog, Gemzar, Evista, and Actos)

Manufacturing Update

100%

80%

60%

40%

20%

1999

2000

2001

2002

2003

As a result of preapproval plant inspections for Zyprexa
IntraMuscular and Forteo in early 2001, the FDA in-
formed us of a number of observations and issued a
warning letter regarding adherence to current Good
Manufacturing Practices (cGMP) regulations. In re-
sponse, we have been implementing comprehensive,
companywide improvements in our manufacturing op-
erations. In the fall of 2002, we provided the FDA with a
comprehensive plan to upgrade our manufacturing and
quality operations, particularly at our injectable and dry
products facilities in Indianapolis.

In late October 2003, the FDA advised us that the
agency now considers our injectable and dry products
facilities in Indianapolis to have reached a level of cGMP
compliance that will allow for FDA preapproval site
inspections for products under review. No further regu-
latory action is expected at this time. In December 2003,
a preapproval site inspection for Zyprexa IntraMuscular
was successfully completed. Although the FDA assess-
ment is an important milestone, we still have consider-
able work to do to reach our ultimate goal of building
and sustaining world-class manufacturing, product and
process development, and quality capabilities.

Acquisition of Applied Molecular Evolution, Inc.

In November 2003, we agreed to acquire AME in a cash
and stock transaction for approximately $400 million,
net of the cash acquired. We expect to close the merger
in the ﬁ rst quarter of 2004. In addition to acquiring the
rights to two compounds currently under development,
we expect the acquisition of AME to create synergies
that will accelerate our ability to discover and optimize
biotherapeutic drugs for cancer, inﬂ ammatory dis-
eases, and critical care, as well as diabetes and obesity,
areas where proteins are of great therapeutic beneﬁ t.
See Note 3 to the consolidated ﬁ nancial statements for
additional information regarding the acquisition of AME.

Legislative-Related Activity and Litigation

In the United States, prescription drugs are subject
to increasing pricing pressure at both the federal and
state levels. In December 2003, President Bush signed
into law the Medicare Prescription Drug, Improvement
and Modernization Act of 2003 (MMA), providing a pre-
scription drug beneﬁ t under the Medicare program be-
ginning in 2006. This is expected to put downward pres-
sure on prescription drug prices. This pressure may
be offset by volume increases, but the business impact
of this legislation will not be known until implementa-
tion in 2006. While the MMA retains the authority of the
Secretary of Health and Human Services to prohibit the
importation of prescription drugs, several bills have
been introduced that would remove that authority and
allow for the immediate importation of products into the
U.S. regardless of their safety or cost. Such legislation
would likely have a negative effect on our U.S. sales.
As a result of the passage of the MMA, all the
aged and many of the disabled Medicaid recipients will
receive their beneﬁ ts through the Medicare program in
the future. This should relieve some state budget pres-
sures but is unlikely to result in less pricing pressure
at the state level. A number of states have begun to
implement supplemental rebates and restricted formu-
laries in their Medicaid programs. Several states are
also attempting to extend discounted Medicaid prices to
non-Medicaid patients. Additionally, over 25 states are
considering proposals that would result in the importa-
tion of prescription drugs for state employees, state
beneﬁ ciaries, and, in some cases, state citizens. As a
result, we expect pressures on pharmaceutical pricing
to continue.

International operations are also generally subject

to extensive price and market regulations, and there
are many proposals for additional cost-containment
measures, including proposals that would directly or
indirectly impose additional price controls or reduce the
value of our intellectual property protection.

Certain generic manufacturers have challenged

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our U.S. compound patent for Zyprexa and are seek-
ing permission to market generic versions of Zyprexa
prior to the patent expiration in 2011. We expect the trial
regarding the defense of these patents, which began in
January 2004, to conclude in the ﬁ rst quarter of 2004. A
ruling from the trial court is expected in the second or
third quarter of 2004 with appeals expected to follow.
See the Legal and Environmental Matters section for
further information.

Revenues
($ millions)

7
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4
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With the launch of Strattera,
we now have 10 products with
annual net revenues in excess
of $300 million. Four of these
products—Zyprexa, Humulin,
Gemzar, and Humalog—had net
revenues in excess of $1 billion
in 2003 and Zyprexa became
our first product with net sales
in excess of $4 billion.

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OPERATING RESULTS—2003

Sales

Our worldwide sales for 2003 increased 14 percent,
to $12.58 billion, due primarily to the strong perfor-
mance of Zyprexa, a treatment for schizophrenia, acute
bipolar mania, and bipolar maintenance; diabetes care
products; Gemzar, an oncolytic product; and Evista, an
osteoporosis treatment and prevention agent; and the
sales related to the launches of Strattera, Cialis, and
Forteo. Sales in the U.S. increased 10 percent, to
$7.17 billion. Sales outside the U.S. increased 19 per-
cent, to $5.41 billion. Worldwide sales reﬂ ected a
volume increase of 7 percent with global selling prices
contributing 2 percent and an increase due to favorable
changes in exchange rates contributing 5 percent.

Zyprexa had worldwide sales of $4.28 billion in
2003, an increase of 16 percent. Sales in the U.S. in-
creased 4 percent, to $2.64 billion. Continuing competi-
tive pressures contributed to slower sales growth in
the U.S. In September 2003, the FDA requested updated
product labeling for all atypical antipsychotics that
includes a warning statement about the risk of diabe-
tes. The FDA’s decision to implement class labeling
reinforces our long-standing position that the risk for
diabetes should be considered among patients with se-
vere mental illness regardless of medication choice. In
early 2004, the American Diabetes Association issued an

opinion paper, which states that second-generation an-
tipsychotics differ in their diabetes risk proﬁ les. These
ﬁ ndings are in direct conﬂ ict with the FDA’s recent class
labeling language. Despite an increasingly competi-
tive environment, we believe the product, together with
Symbyax, still has sales growth potential in the U.S. We
expect U.S. sales to beneﬁ t from the recent approval of a
bipolar maintenance indication and the anticipated near-
term approval of Zyprexa IntraMuscular. Sales outside
the U.S. increased 42 percent, to $1.64 billion. Excluding
the impact of exchange rates, our sales outside the U.S.
grew 26 percent. The strong international sales growth
of Zyprexa was primarily driven by increased unit vol-
ume attributable to the bipolar mania indication and the
ongoing conversion from typical to atypical antipsychot-
ics and, to a lesser extent, the impact of exchange rates.
Zyprexa recorded strong growth in several key markets,
including several major European Union countries and in
Japan. We expect continued strong overseas growth of
the product in 2004. Zyprexa recently received U.S. and
European approvals for bipolar maintenance. Zyprexa
IntraMuscular has recently been launched in Australia,
Canada, and Europe, and we currently expect U.S. ap-
proval in the ﬁ rst half of 2004.

Diabetes care products, composed primarily of Hu-
mulin, biosynthetic human insulin; Humalog, our insulin
analog; and Actos, an oral agent for the treatment of
type 2 diabetes, had aggregate worldwide revenues of
$2.57 billion in 2003, an increase of 12 percent. Dia-
betes care revenues in the U.S. increased 10 percent,
to $1.57 billion. Diabetes care revenues outside the
U.S. increased 17 percent, to $1.00 billion. Humulin had
worldwide sales of $1.06 billion, an increase of 6 percent.
Humulin sales in the U.S. decreased 2 percent, to
$507.5 million. Humulin sales outside the U.S. in-
creased 13 percent, to $552.9 million. Humalog became
a billion-dollar product in 2003 with worldwide sales of
$1.02 billion, an increase of 22 percent. Humalog sales
in the U.S. increased 25 percent, to $658.6 million.
Humalog sales outside the U.S. increased 19 percent, to
$362.7 million. In 2004, we expect our worldwide insulin
franchise to have little or no growth primarily due to ex-
pected continued competitive pressure on prescription
volume. Actos revenues, the majority of which repre-
sent service revenues from a copromotion agreement
in the U.S. with Takeda Pharmaceuticals North America
(Takeda), increased 10 percent in 2003, to $431.2 mil-
lion. Actos is manufactured by Takeda Chemical Indus-
tries, Ltd., and sold in the U.S. by Takeda.

Gemzar became a billion-dollar product in 2003
with worldwide sales of $1.02 billion, an increase of 17
percent. Sales in the U.S. increased 8 percent, to $522.4
million. Sales outside the U.S. increased 27 percent, to
$499.3 million. We recently submitted Gemzar in the U.S.
for the treatment of late-stage metastatic breast cancer.
Evista had worldwide sales of $922.1 million in

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2003, an increase of 12 percent. Sales in the U.S. in-
creased 5 percent, to $655.5 million. The U.S. growth
was negatively affected by the exit of patients from the
osteoporosis prevention market. In early 2004, Evista
received regulatory approval in Japan. Sales outside
the U.S. increased 36 percent, to $266.6 million.

Prozac, an antidepressant; Prozac Weekly™; and
Sarafem®, a prescription treatment for premenstrual
dysphoric disorder, a severe form of premenstrual syn-
drome (collectively, ﬂ uoxetine products), had combined
worldwide sales of $645.1 million, a decrease of 12 per-
cent. Fluoxetine product sales decreased 12 percent, to
$398.6 million, in the U.S. and decreased 13 percent, to
$246.5 million, outside the U.S. The declines were due
to continuing generic competition.

Anti-infectives had worldwide sales of $489.9 mil-

lion in 2003, a decrease of 15 percent. Sales outside
the U.S. decreased 19 percent, to $420.1 million. Lower
worldwide sales of anti-infectives were primarily due to
continuing generic competition.

In November 2002, the FDA approved Strattera for
the treatment of attention-deﬁ cit hyperactivity disorder
in children, adolescents, and adults. Strattera sales
were $370.3 million for 2003. Recently, regulatory
authorities approved Strattera for marketing in Austra-
lia, Argentina, and Mexico. We expect Strattera to be a
signiﬁ cant contributor to our sales growth in 2004.

ReoPro, a cardiovascular agent, had worldwide
sales of $364.4 million in 2003, a decrease of 5 percent.
Sales in the U.S. decreased 19 percent, to $201.4 mil-
lion, due to continuing competitive pressures, and sales
outside the U.S. increased 20 percent, to $163.0 million.
Cialis was launched in 2003 in several markets
outside the U.S. by Lilly and ICOS. Cialis was launched
in the U.S. in early December 2003. Cialis had total
sales of $203.3 million in 2003. Of this total, $73.5 mil-
lion represent sales in our exclusive territories and are
reported in our net sales. The remaining Cialis sales
relate to the joint-venture territories of Lilly ICOS LLC
(North America and Europe) and are reported in the
Lilly ICOS joint-venture income statement along with
related expenses. We report our 50 percent share of the
operating results of the joint venture in our net other
income. In early 2004, Lilly ICOS began a direct-to-con-
sumer advertising campaign in the U.S. We will con-
tinue to increase our direct-to-consumer advertising
activities in print and on television.

Xigris, a treatment for severe sepsis, had world-

wide sales of $160.4 million in 2003, an increase of
60 percent compared with 2002. Sales in the U.S. were
$109.2 million in 2003, an increase of 22 percent com-
pared with 2002. Sales outside the U.S. totaled
$51.2 million in 2003.

Forteo was ofﬁ cially launched in December 2002
and we received an approval in Europe during June 2003.
Forteo sales were $65.3 million in 2003. We have imple-

mented a staged launch of Forteo in the U.S. During the
ﬁ rst stage in 2003, we focused on approximately 8,000
doctors who specialize in the treatment of osteoporosis.
We are currently expanding our selling efforts in the next
stage of our launch to encompass an additional 15,000
primary care physicians who treat osteoporosis.

Animal health products had worldwide sales of
$726.6 million in 2003, an increase of 5 percent. Sales
in the U.S. increased 2 percent, to $309.8 million. Sales
outside the U.S. increased 7 percent, to $416.8 million.

Payments to states under federally mandated Med-

icaid rebate and state pharmaceutical assistance pro-
grams reduced 2003 sales by $567.6 million compared
with $438.2 million in 2002. The increase is primarily
due to increased U.S. sales of Zyprexa and higher use of
Zyprexa among Medicaid patients.

Gross Margin, Costs, and Expenses

The 2003 gross margin decreased to 78.7 percent of
sales compared with 80.4 percent for 2002. This de-
crease was attributed primarily to increased costs
associated with quality improvements and growth in
capacity of our manufacturing operations and the impact
of foreign exchange rates, offset partially by favorable
changes in product mix due to growth in sales of higher
margin products.

%
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7
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%
0
.
9
7

Gross Margin
(as a percent of total net sales)

Gross margin as a percent of
sales decreased by 1.7 percent-
age points to 78.7 percent. This
decline was primarily due to
continued quality improvements,
capacity growth in our manu-
facturing operations, and the
impact of foreign exchange
rates, offset partially by
favorable changes in product
mix due to growth in higher
margin products such as
Zyprexa, Gemzar, Evista, and
the newly launched Strattera.

1999

2000

2001

2002

2003

Operating expenses (the aggregate of research
and development and marketing and administrative
expenses) increased 15 percent in 2003. Investment
in research and development increased 9 percent, to
$2.35 billion, due to increased clinical-trial expenses,
the impact of foreign exchange rates, and milestone
payments to Amylin for successful Phase III studies
of exenatide. Maintaining our strong commitment to
innovation, we invested approximately 19 percent of
our sales in research and development efforts in 2003.
Marketing and administrative expenses increased
18 percent compared with 2002, attributable primar-
ily to increased marketing expenses in support of the

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F

new product launches, the preparation for anticipated
launches, and the impact of foreign exchange rates.

2001
• In the third and fourth quarters of 2001, we recognized

%
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Research and Development
($ millions; percent of net
sales)

Research and development
expenditures increased by
9 percent, to $2.4 billion, in 2003.
At 19 percent of net sales, we
continue to lead our industry
peer group in reinvesting
proceeds from sales in further
research and development. This
significant financial investment
in our pipeline of products
supports our commitment to
develop best-in-class and first-
in-class medicines to provide
answers for the unmet medical
needs of our customers.

%
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Net other income for 2003 was $203.1 million, a de-
crease of $90.6 million. The decrease was primarily due
to lower interest and miscellaneous income. We report
our 50 percent share of the operating results of the Lilly
ICOS joint venture in our net other income. For 2003,
our net loss from the joint venture was $52.4 million,
compared with $37.8 million in 2002.

The effective tax rate for 2003 was 21.5 percent
compared with 21.7 percent for 2002. See Note 11 to the
consolidated ﬁ nancial statements for additional infor-
mation.

OPERATING RESULTS—2002

Financial Summary

Net income was $2.71 billion, or $2.50 per share, in
2002 and $2.78 billion, or $2.55 per share, in 2001, a
decline of 3 percent and 2 percent, respectively. Com-
parisons between 2002 and 2001 are inﬂ uenced by the
impact of the 2002 items discussed in the Executive
Overview and the items discussed immediately below
that are reﬂ ected in our operating results. In addition to
the impact of those items, net income and earnings per
share for 2002 declined primarily due to the result of
lower sales of Prozac partially offset by sales growth of
several key products, lower interest expense, and lower
operating expenses. Earnings per share for 2002 ben-
eﬁ ted slightly from a lower number of shares outstand-
ing, resulting from our share repurchase program.

Certain items, reﬂ ected in our operating results

for 2002 and 2001, should be considered in compar-
ing the two years. The signiﬁ cant charge for 2002 is
summarized in the Executive Overview. The 2001 items
are summarized as follows (see Notes 3, 4, and 6 to the
consolidated ﬁ nancial statements for additional infor-
mation).

charges of $190.5 million (pretax) for acquired
in-process research and development related to
collaboration arrangements with Isis Pharmaceuticals,
Inc. (Isis); 3M Company; and Bioprojet, Société Civile de
Recherche (Bioprojet), which decreased earnings per
share by approximately $.05 in the third quarter and
$.06 in the fourth quarter of 2001.

• We recognized charges of $121.4 million (pretax)
associated with asset impairment and other site
charges in the third quarter of 2001 due to actions
taken as a result of the assessment of our worldwide
manufacturing capacity, which decreased earnings per
share by approximately $.07.

• We recognized a charge of $45.2 million (pretax) from
the repurchase of higher interest rate debt in the third
and fourth quarters of 2001, which decreased earnings
per share by approximately $.02 in the third quarter
and $.01 in the fourth quarter of 2001.

Sales

Our worldwide sales for 2002 decreased 4 percent, to
$11.08 billion, due primarily to the decline in sales of
Prozac in the U.S. resulting from the loss of patent pro-
tection in August 2001. Partially offsetting this decline
was sales growth of Zyprexa, diabetes care products,
Gemzar, Evista, and Xigris. Sales in the U.S. decreased
11 percent, to $6.54 billion. Sales outside the U.S.
increased 9 percent, to $4.54 billion. Excluding Prozac,
our worldwide and U.S. sales increased 8 percent and
7 percent, respectively. Worldwide sales reﬂ ected a
volume decline of 4 percent, while global selling prices
and exchange rates remained essentially ﬂ at.

Zyprexa had worldwide sales of $3.69 billion in
2002, an increase of 20 percent. Sales in the U.S. in-
creased 16 percent, to $2.53 billion. Sales outside the
U.S. increased 27 percent, to $1.16 billion, beneﬁ ting,
in part, from the launch of Zyprexa in Japan during the
second quarter of 2001. In 2002, our European sales
forces began promoting Zyprexa for use in treating
manic episodes associated with bipolar disorder.

Diabetes care products had aggregate worldwide

revenues of $2.29 billion in 2002, an increase of
8 percent. Diabetes care revenues in the U.S. increased
5 percent, to $1.43 billion. Diabetes care revenues
outside the U.S. increased 12 percent, to $859.2 mil-
lion. Humulin had worldwide sales of $1.00 billion,
a decrease of 5 percent due to the continued shift by
patients to Humalog and Humalog mixture products
and to increased competition. Humulin sales in the U.S.
decreased 11 percent, to $515.4 million. Humulin sales
outside the U.S. increased 1 percent, to $488.6 mil-
lion. Humalog had worldwide sales of $834.2 million,
an increase of 33 percent. Humalog sales in the U.S.

CONSOLIDATED STATEMENTS OF INCOME

Eli Lilly and Company and Subsidiaries
(Dollars in millions, except per-share data)

Year Ended December 31

2003

2002

2001

Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$12,582.5

$11,077.5

$11,542.5

Cost of sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2,675.1

2,176.5

2,160.2

Research and development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2,350.2

2,149.3

2,235.1

Marketing and administrative . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

4,055.4

3,424.0

3,417.4

Acquired in-process research and development (Note 3). . . . . . . . . . .

—

84.0

190.5

Asset impairments, restructuring, and other special

charges (Note 4). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

382.2

Interest expense . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

61.0

—

79.7

121.4

191.7

Other income—net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

(203.1)
9,320.8

(293.7)
7,619.8

(280.7)
8,035.6

Income before income taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

3,261.7

3,457.7

3,506.9

Income taxes (Note 11) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

700.9

749.8

726.9

Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 2,560.8

$ 2,707.9

$ 2,780.0

Earnings per share—basic (Note 10). . . . . . . . . . . . . . . . . . . . . . . . . . .

$2.38

$2.51

Earnings per share—diluted (Note 10) . . . . . . . . . . . . . . . . . . . . . . . . .

$2.37

$2.50

$2.58

$2.55

See notes to consolidated ﬁ nancial statements.

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sociated with capacity increases for certain growth
and new products, and higher inventory losses. These
declines in gross margin were partially offset by favor-
able changes in product mix due to growth in sales of
other higher margin products, such as Zyprexa, Gem-
zar, Evista, and diabetes care products, and favorable
manufacturing throughput from increased volume of
product manufactured.

Operating expenses decreased 1 percent in 2002.
Research and development expenses decreased 4 per-
cent, to $2.15 billion, due primarily to lower late-stage
clinical-trial costs as more products were awaiting
regulatory approval. Despite the decline, we invested
approximately 19 percent of our sales in research and
development efforts in 2002. Marketing and administra-
tive expenses remained essentially ﬂ at compared with
2001 despite the continued expansion of our worldwide
sales force and increased marketing efforts in support
of our growth products and upcoming product launch-
es. Operating expenses were also reduced due to lower
incentive compensation expenses, reimbursement from
collaboration partners, and cost containment, none of
which were individually material.

During 2002, we expensed $84.0 million for ac-
quired in-process research and development costs
related to the exenatide collaboration arrangement with
Amylin. Exenatide is in the development phase and no
alternative future uses were identiﬁ ed.

Net other income for 2002 was $293.7 million, an
increase of $13.0 million. The increase was primarily due
to a combination of income recognized from upfront and
milestone payments from Quintiles Transnational Corp.
(Quintiles) as part of a Cymbalta commercialization agree-
ment and income recognized from InterMune, Inc., related
to out-licensing oritavancin in 2001, offset primarily by
lower interest income due to lower interest rates.

Interest expense for 2002 decreased $112.0 million,
to $79.7 million, primarily due to lower variable interest
rates paid on our debt.

The effective tax rate for 2002 was 21.7 percent com-
pared with 20.7 percent for 2001. See Note 11 to the con-
solidated ﬁ nancial statements for additional information.

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increased 34 percent, to $528.3 million. Humalog sales
outside the U.S. increased 31 percent, to $305.9 million.
We received service revenues of $391.7 million in 2002,
an increase of 9 percent, related to sales of Actos.

Gemzar had worldwide sales of $874.6 million in

2002, an increase of 21 percent, driven primarily by
strong underlying product demand. Sales in the U.S.
increased 16 percent, to $482.1 million. Sales outside
the U.S. increased 28 percent, to $392.5 million.

Evista had worldwide sales of $821.9 million in 2002,

an increase of 24 percent. Sales in the U.S. increased
19 percent, to $626.1 million. Sales outside the U.S.
increased 41 percent, to $195.8 million. Sales beneﬁ ted
from strong underlying product demand driven, in part,
by competitive developments in the second half of 2002.

Fluoxetine products had combined worldwide sales

of $733.7 million, a decrease of 63 percent. Fluoxetine
product sales in the U.S. decreased 73 percent, to
$451.7 million, due to generic competition for Prozac
beginning in early August 2001. Fluoxetine product
sales outside the U.S. decreased 15 percent, to $282.0
million, primarily due to continuing generic competition.
Anti-infectives had worldwide sales of $577.4 million
in 2002, a decrease of 23 percent. Sales of anti-infectives
in the U.S. decreased 55 percent, to $58.5 million. Sales
outside the U.S. decreased 16 percent, to $518.9 million.
Lower sales of anti-infectives were due to continuing
competitive pressures and to manufacturing and supply
issues with respect to certain injectable antibiotics.
ReoPro had worldwide sales of $384.0 million
in 2002, a decrease of 11 percent. Sales in the U.S.
decreased 20 percent, to $248.3 million, due to continu-
ing competitive pressures, and sales outside the U.S.
increased 14 percent, to $135.7 million.

At the end of November 2001, we launched Xigris in
the United States. In October 2002, we launched Xigris in
a number of European countries. Worldwide Xigris sales
were $100.2 million in 2002 compared with $21.2 million
in 2001. Sales in the U.S. were $89.3 million in 2002.
Animal health products had worldwide sales of
$693.1 million in 2002, an increase of 1 percent. Sales in
the U.S. decreased 6 percent, to $304.2 million, due pri-
marily to declines in our cattle and swine products. Sales
outside the U.S. increased 7 percent, to $388.9 million.
Payments to states under federally mandated
Medicaid rebate and state pharmaceutical assistance
programs reduced 2002 sales by $438.2 million com-
pared with $475.0 million in 2001.

Gross Margin, Costs, and Expenses

The 2002 gross margin decreased to 80.4 percent of
sales compared with 81.3 percent for 2001. This de-
crease was attributed primarily to the decline in sales
of Prozac, a higher margin product, and increased
costs associated with cGMP improvements, costs as-

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CONSOLIDATED BALANCE SHEETS

Eli Lilly and Company and Subsidiaries
(Dollars in millions)

December 31

2003

2002

Assets
Current Assets
Cash and cash equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Short-term investments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Accounts receivable, net of allowances of $79.5 (2003) and $66.4 (2002) . . . . . . .
Other receivables. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Inventories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Deferred income taxes (Note 11) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Prepaid expenses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total current assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Other Assets
Prepaid pension (Note 12) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Investments (Note 5) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Sundry (Note 8) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 2,756.3
957.0
1,854.7
477.6
1,963.0
500.6
249.5
8,758.7

1,613.3
3,374.6
1,392.5
6,380.4

$ 1,945.9
1,708.8
1,670.3
403.9
1,495.4
331.7
248.1
7,804.1

1,515.4
3,150.4
1,279.1
5,944.9

Property and Equipment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

6,539.0
$21,678.1

5,293.0
$19,042.0

Liabilities and Shareholders’ Equity
Current Liabilities
Short-term borrowings (Note 6) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Accounts payable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Employee compensation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Dividends payable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Income taxes payable (Note 11) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other liabilities (Note 8) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total current liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 196.5
875.9
387.4
398.3
1,749.8
1,942.7
5,550.6

$ 545.4
676.9
231.7
375.8
1,761.9
1,471.8
5,063.5

Other Liabilities
Long-term debt (Note 6) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other noncurrent liabilities (Note 8) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

4,687.8
1,674.9
6,362.7

4,358.2
1,346.7
5,704.9

Commitments and contingencies (Note 13) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

—

Shareholders’ Equity (Notes 7 and 9)
Common stock—no par value
Authorized shares: 3,200,000,000

Issued shares: 1,124,677,097 (2003) and 1,123,451,408 (2002). . . . . . . . . . . . . . .
Additional paid-in capital . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Retained earnings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Employee beneﬁ t trust . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Deferred costs—ESOP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Accumulated other comprehensive loss (Note 14) . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

702.3
2,610.0
9,470.4
(2,635.0)
(118.6)
(160.1)
9,869.0

702.1
2,610.0
8,500.1
(2,635.0)
(123.3)
(670.8)
8,383.1

Less cost of common stock in treasury
2003—951,578 shares
2002—1,008,292 shares . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

104.2
9,764.8
$21,678.1

109.5
8,273.6
$19,042.0

See notes to consolidated ﬁ nancial statements.

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FINANCIAL CONDITION

As of December 31, 2003, cash, cash equivalents, and
short-term investments totaled approximately
$3.71 billion compared with $3.65 billion at December
31, 2002. The increase in cash, cash equivalents, and
short-term investments was primarily due to cash
generated from operations and net debt issuances,
partially offset by capital expenditures, dividends paid,
and share repurchases. We acquired approximately 3.0
million shares, for $276.8 million, during 2003 pursuant
to our previously announced $3 billion share repur-
chase program. We have now completed $2.08 billion of
purchases in connection with that program. We do not
expect any signiﬁ cant share repurchases in 2004.

Our inventories increased by $467.6 million during

2003, to $1.96 billion, due primarily to exchange rate
translation of overseas inventories to adjust for U.S.
dollar weakness and to the buildup of inventory for new
product launches and our growth products.

6
.
6
0
7
,
1
$

9
.
0
3
1
,
1
$

0
.
4
8
8
$

Capital Expenditures
($ millions)

Capital expenditures increased
51 percent from 2002. The
continued heavy investment
supported various manufac-
turing and research initiatives
and related infrastructure. In
2004, the company expects near-
term capital expenditures to
increase from 2003 levels to
prepare for the growth of our
diabetes care products, future
products in development, and
expanded research and
development activities.

9
.
7
7
6
$

3
.
8
2
5
$

1999
1999

2000
2000

2001
2001

2002
2002

2003
2003

Capital expenditures of $1.71 billion during 2003
were $575.7 million more than in 2002 as we continued
to invest in manufacturing and research and develop-
ment initiatives and related infrastructure. We expect
near-term capital expenditures to increase from 2003
levels primarily to continue to prepare for the growth
of our diabetes care products, future products, and
increased research and development activities.

Total debt at December 31, 2003, was $4.88 billion,

a decrease of $19.3 million from December 31, 2002.
In 2003, we issued $830.0 million of long-term debt,
repaid $540.0 million of long-term debt, and made net
repayments of $247.3 million of short-term debt. The
decrease in reported debt was caused by the decline in
the SFAS 133 fair value adjustment discussed further
in Note 6 to the consolidated ﬁ nancial statements.
Our current debt ratings from Standard & Poor’s and
Moody’s remain at AA and Aa3, respectively.

4
3
.
1
$

4
2
.
1
$

2
1
.
1
$

4
0
.
1
$

2
9
.
0
$

Dividends Paid Per Share
(dollars)

Dividends paid during 2003
increased to $1.34 per share.
This constitutes the 36th
consecutive increase in annual
dividends. The company also
continues this tradition into 2004
by declaring a first-quarter 2004
dividend of $.355 per share, a
6 percent increase over first-
quarter 2003. This record clearly
reflects the company’s continued
commitment to delivering
outstanding shareholder value.

1999

2000

2001

2002

2003

Dividends of $1.34 per share were paid in 2003, an
increase of 8 percent from 2002. In the fourth quarter
of 2003, effective for the ﬁ rst-quarter dividend in 2004,
the quarterly dividend was increased to $.355 per share
(a 6 percent increase), resulting in an indicated annual
rate for 2004 of $1.42 per share. The year 2003 was the
119th consecutive year in which we made dividend pay-
ments and the 36th consecutive year in which dividends
have been increased.

We believe that cash generated from operations,

along with available cash and cash equivalents, will be
sufﬁ cient to fund most of our operating needs, includ-
ing debt service, capital expenditures, and dividends in
2004. We will likely issue additional debt in 2004 to fund
remaining cash requirements. We believe that, if neces-
sary, amounts available through our existing commer-
cial paper program should be adequate to fund maturi-
ties of short-term borrowings. Our commercial paper
program is also currently backed by $1.24 billion of un-
used committed bank credit facilities. Various risks and
uncertainties, including those discussed in the Financial
Expectations for 2004 section, may affect our operating
results and cash generated from operations.

In the normal course of business, our operations
are exposed to ﬂ uctuations in interest rates and cur-
rency values. These ﬂ uctuations can vary the costs
of ﬁ nancing, investing, and operating. We address a
portion of these risks through a controlled program of
risk management that includes the use of derivative
ﬁ nancial instruments. The objective of controlling these
risks is to limit the impact on earnings of ﬂ uctuations
in interest and currency exchange rates. All derivative
activities are for purposes other than trading.

Our primary interest rate risk exposure results
from changes in short-term U.S. dollar interest rates.
In an effort to manage interest rate exposures, we
strive to achieve an acceptable balance between ﬁ xed
and ﬂ oating rate debt positions and may enter into
interest rate derivatives to help maintain that balance.

Based on our overall interest rate exposure at Decem-
ber 31, 2003 and 2002, including derivatives and other
interest rate risk-sensitive instruments, a hypothetical
10 percent change in interest rates applied to the fair
value of the instruments as of December 31, 2003 and
2002, respectively, would have no material impact on
earnings, cash ﬂ ows, or fair values of interest rate risk-
sensitive instruments over a one-year period.

Our foreign currency risk exposure results from
ﬂ uctuating currency exchange rates, primarily the U.S.
dollar against the euro and the Japanese yen. We face
transactional currency exposures that arise when we
enter into transactions, generally on an intercompany
basis, denominated in currencies other than the local
currency. We also face currency exposure that arises
from translating the results of our global operations to
the U.S. dollar at exchange rates that have ﬂ uctuated
from the beginning of the period. We use forward con-
tracts and purchased options to manage our foreign cur-
rency exposures. Our policy outlines the minimum and
maximum hedge coverage of such exposures. Gains and
losses on these derivative positions offset, in part, the
impact of currency ﬂ uctuations on the existing assets,
liabilities, commitments, and anticipated revenues. Con-
sidering our derivative ﬁ nancial instruments outstanding
at December 31, 2003 and 2002, a hypothetical 10 per-
cent change in exchange rates (primarily against the U.S.
dollar) as of December 31, 2003 and 2002, respectively,
would have no material impact on earnings, cash ﬂ ows,
or fair values of foreign currency rate risk-sensitive

%
3
.
5
5

%
9
.
3
5

%
0
.
6
4

%
5
.
7
3

%
3
.
2
4

%
2
.
5
3

%
4
.
8
2

Return on Shareholders’ Equity
(based on income from continuing
operations divided by average
shareholders’ equity)

Return on shareholders’ equity
declined in 2003, to 28.4 percent.
This decline is primarily
attributable to significant
investments in sales and
marketing activities in support
of our existing key growth
products and to prepare for
anticipated product launches.
We also made substantial invest-
ments in our manufacturing
operations and research and
development activities.

%
2
.
8
2

%
1
.
6
2

%
8
.
3
2

instruments over a one-year period. These calculations
do not reﬂ ect the impact of the exchange gains or losses
on the underlying positions that would be offset, in part,
by the results of the derivative instruments.

Off-Balance Sheet Arrangements and Contractual
Obligations

We have no off-balance sheet arrangements that have
a material current effect or that are reasonably likely to
have a material future effect on our ﬁ nancial condition,
changes in ﬁ nancial condition, revenues or expenses,
results of operations, liquidity, capital expenditures, or
capital resources. We do acquire assets still in develop-
ment and enter into research and development ar-
rangements with third parties that often require mile-
stone and royalty payments to the third party contingent
upon the occurrence of certain future events linked to
the success of the asset in development. Milestone pay-
ments may be required contingent upon the successful
achievement of an important point in the development
life cycle of the pharmaceutical product (e.g., approval
of the product for marketing by the appropriate regula-
tory agency). If required by the arrangement, we may
have to make royalty payments based upon a percent-
age of the sales of the pharmaceutical product in the
event that regulatory approval for marketing is ob-
tained. Because of the contingent nature of these pay-
ments, they are not included in the table of contractual
obligations below.

These arrangements are not material individually.

However, if milestones for multiple products covered by
these arrangements would happen to be reached in the
same year, the aggregate charge to expense could be
material to the results of operations in any one period.
The risk inherent in pharmaceutical development makes
it unlikely that this will occur as the failure rate for
products in development is very high. In addition, these
arrangements often give us the discretion to unilaterally
make the decision to stop development of the product,
which would allow us to avoid making the contingent pay-
ments; however, we are unlikely to cease development if
the compound successfully achieves clinical testing ob-
jectives. We also note that, from a business perspective,
we view these payments as positive because they signify
that the product is successfully moving through develop-
ment and is now generating or is more likely to generate
cash ﬂ ows from sales of products.

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Our current noncancelable contractual obligations that will require future cash payments are as follows (in mil-

lions):

Payments Due by Period

Total

Less Than 1 Year

1-3 Years

3-5 Years

More Than 5 Years

Long-term debt, including interest payments (1) . . . . $11,759.9
174.7
Capital lease obligations. . . . . . . . . . . . . . . . . . . . . . . .
339.5
Operating leases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Purchase obligations (2) . . . . . . . . . . . . . . . . . . . . . . . . .
2,528.2
Other long-term liabilities reﬂ ected on our
balance sheet under GAAP (3) . . . . . . . . . . . . . . . . .
458.2
Other (4) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
210.7
Total . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $15,471.2

$ 367.6
26.3
82.5
2,243.3

$1,417.1
39.8
122.6
142.3

$ 894.8
28.8
90.2
106.8

—
190.7
$2,910.4

81.6
12.5
$1,815.9

81.6
7.5
$1,209.7

$9,080.4
79.8
44.2
35.8

295.0
—

$9,535.2

(1) Our long-term debt obligations include both our expected principal and interest obligations. The rate in effect
at December 31, 2003, was used to compute the amount of the contractual obligation for the variable rate debt
instruments.

(2) We have included the following:

• Purchase obligations, consisting primarily of all open purchase orders at our signiﬁ cant operating locations
as of December 31, 2003. Some of these purchase orders may be cancelable; however, for purposes of this
disclosure, we have not distinguished between cancelable and noncancelable purchase obligations.

• Contractual payment obligations with each of our signiﬁ cant vendors, which are noncancelable and are not

contingent.

(3) We have included our long-term liabilities consisting primarily of our minimum pension funding requirements,

nonqualiﬁ ed supplemental pension funding requirements, and deferred compensation liabilities.

(4) This category comprises primarily cash to be used in the AME acquisition and loan funding requirements to our
collaboration partners. The acquisition of AME requires us to pay 20 percent of the purchase price as cash. The
amount included in the other category represents an estimate of the purchase price that will be paid in cash.
See Note 3 to the consolidated ﬁ nancial statements for additional information regarding the acquisition of AME.

The contractual obligations table above is current as of December 31, 2003. The amount of these obligations
can be expected to change materially over time as new contracts are initiated and existing contracts are terminated
or modiﬁ ed.

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APPLICATION OF CRITICAL ACCOUNTING POLICIES

In preparing our ﬁ nancial statements in accordance
with generally accepted accounting principles (GAAP),
we must often make estimates and assumptions that
affect the reported amounts of assets, liabilities,
revenues, expenses, and related disclosures. Some of
those judgments can be subjective and complex, and
consequently actual results could differ from those
estimates. For any given individual estimate or as-
sumption we make, there may also be other estimates
or assumptions that are reasonable; however, we
believe that, given current facts and circumstances,
it is unlikely that applying any such other reasonable
judgment would cause a material adverse effect on our
consolidated results of operations, ﬁ nancial position, or
liquidity for the periods presented in this report.

Our most critical accounting policies are described

below. We have discussed the nature and the inherent
judgment used in the application of our critical account-
ing policies with our audit committee.

Sales Rebate and Discount Accruals

Sales rebate and discount accruals are established in the
same period as the related sales. The rebate/discount
amounts are recorded as a deduction to arrive at our net
sales and are included in other current liabilities. Sales
rebates/discounts that require the use of judgment in the
establishment of the accrual include Medicaid, man-
aged care, long-term-care, hospital, and various other
government programs. We base these accruals primar-
ily upon our historical rebate/discount payments made
to our customer segment groups. We calculate these
rebates/discounts based upon a percent of our sales for
each of our products as deﬁ ned by the statutory rates

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and the contracts with our various customer groups.

The largest of our sales rebate/discount amounts

are rebates associated with sales covered by Medicaid.
Although we generally accrue a liability for Medicaid re-
bates at the time we record the sale (when the product
is shipped), the Medicaid rebate related to that sale is
typically paid up to six months later. In determining the
appropriate accrual amount, we consider our historical
Medicaid rebate payments by product as a percent of
our historical sales as well as any signiﬁ cant changes
in sales trends, an evaluation of the current Medicaid
rebate laws and interpretations, the percent of our
products that are sold to Medicaid recipients, and our
product pricing and current rebate/discount contracts.
We believe that the accruals we have established for
sales rebates and discounts are reasonable and appropri-
ate based on current facts and circumstances. However, it
is possible that other people applying reasonable judg-
ment to the same facts and circumstances could develop a
different accrual amount for sales rebates and discounts.
A 5 percent change in the Medicaid rebate expense we
recognized in 2003 would lead to an approximate $28 mil-
lion effect on our income before income taxes.

Product Litigation Liabilities and Other Contingencies

Product litigation liabilities and other contingencies are,
by their nature, uncertain and are based upon complex
judgments and probabilities. The factors we consider in
developing our product litigation liability reserves and
other contingent liability amounts include the merits and
jurisdiction of the litigation, the nature and the number
of other similar current and past litigation cases, the
nature of the product and the current assessment of
the science subject to the litigation, and the likelihood of
settlement and current state of settlement discussions
if any. In addition, we have accrued for certain product
liability claims incurred, but not ﬁ led, to the extent we
can formulate a reasonable estimate of their costs. We
estimate these expenses based primarily on historical
claims experience and data regarding product usage.

We also consider the insurance coverage we have to

diminish the exposure. In assessing our insurance cov-
erage, we consider the policy coverage limits and exclu-
sions, the potential for denial of coverage by the insur-
ance company, the ﬁ nancial position of the insurers, and
the possibility of and the length of time for collection.
We believe that the accruals and related insurance
recoveries we have established for product litigation li-
abilities and other contingencies are appropriate based on
current facts and circumstances. However, it is possible
that other people applying reasonable judgment to the
same facts and circumstances could develop a different
liability amount for product litigation liabilities and other
contingencies or a different recovery amount from the
insurance companies. A 5 percent change in the product

litigation liabilities and other contingencies accrual would
lead to an approximate $13 million effect on our income
before income taxes; however, much of this effect would
be expected to be offset by recoveries from our insurance
coverages. A 5 percent change in the insurance recoveries
estimate would lead to an approximate $4 million effect
on our income before income taxes.

Pension and Retiree Medical Plan Assumptions

Pension beneﬁ t costs include assumptions for the
discount rate, retirement age, and the expected return
on plan assets. Retiree medical plan costs include
assumptions for the discount rate, retirement age, the
expected return on plan assets, and the health-care-
cost trend rates. These assumptions have a signiﬁ -
cant effect on the amounts reported. In addition to the
analysis below, see Note 12 to the consolidated ﬁ nancial
statements for additional information regarding our
retirement beneﬁ ts.

Periodically, we evaluate the discount rate and the

expected return on plan assets in our deﬁ ned beneﬁ t
pension and retiree health beneﬁ t plans. In evaluating
these assumptions, we consider many factors, includ-
ing an evaluation of the discount rates, expected return
on plan assets and the health-care-cost trend rates
of other companies; our historical assumptions com-
pared with actual results; an analysis of current market
conditions and asset allocations (approximately 85 to
95 percent of which are growth investments); and the
views of leading ﬁ nancial advisers and economists. In
evaluating our expected retirement age assumption,
we consider the retirement ages of our past employees
eligible for pension and medical beneﬁ ts together with
our expectations of future retirement ages.

We believe our pension and retiree medical plan

assumptions are appropriate based upon the above
factors. However, other people applying reasonable
judgment to the same facts and circumstances could
develop a different estimate of these factors. If the
health-care-cost trend rates were to be increased by
one percentage point each future year, the aggregate
of the service cost and interest cost components of the
2003 annual expense would increase by approximately
$15 million. A one-percentage-point decrease would
decrease the aggregate of the 2003 service cost and in-
terest cost by approximately $13 million. If the discount
rate for 2003 were to be changed by a quarter percent-
age point, income before income taxes would change
by approximately $17 million. If the expected return on
plan assets for 2003 were to be changed by a quarter
percentage point, income before income taxes would
change by approximately $10 million. If our assumption
regarding the expected age of future retirees for 2003
were adjusted by one year, that would affect our income
before income taxes by approximately $24 million.

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Valuation Allowances Recorded Against Deferred Tax
Assets

We have recorded valuation allowances against certain
of our deferred tax assets, primarily those that have
been generated from net operating losses in certain
taxing jurisdictions. In evaluating whether we would
more likely than not recover these deferred tax assets,
we have not assumed any future taxable income or tax
planning strategies in the jurisdictions associated with
these carryforwards. Implementation of tax plan-
ning strategies to recover these deferred tax assets or
future income generation in these jurisdictions could
lead to the reversal of these valuation allowances and a
reduction of income tax expense.

We believe that our estimates for the valuation al-

lowances reserved against the deferred tax assets are
appropriate based on current facts and circumstances.
However, other people applying reasonable judgment to
the same facts and circumstances could develop a dif-
ferent estimate of these factors. A 5 percent change in
the valuation allowance would result in a change in net
income of approximately $21 million.

FINANCIAL EXPECTATIONS FOR 2004

For the ﬁ rst quarter and full year of 2004, we expect
earnings per share to be in the range of $.65 to $.67
and $2.80 to $2.85, respectively. This earnings guidance
excludes material unusual items and the substantial
one-time charge we expect to report in the ﬁ rst quarter
of 2004 for acquired in-process research and develop-
ment related to the merger with AME, the amount of
which has not been determined at this time. We are
not currently aware of material unusual items that will
occur in 2004. Further, this guidance reﬂ ects ongoing
domestic competitive pressures on Zyprexa, which we
will continue to monitor. It also includes the projected
beneﬁ ts for Zyprexa associated with the recently ap-
proved bipolar maintenance indication, as well as Sym-
byax and the anticipated near-term approval of Zyprexa
IntraMuscular. For the full-year 2004, we expect low
double-digit sales growth, gross margins as a percent
of sales to be essentially ﬂ at compared with the prior
year, marketing and administrative expenses to grow
in the low double digits, and research and development
expenses to grow in the mid-teens. Further, we expect
that other income/deductions (net other income less
interest expense) will be approximately $100 million
to $120 million for 2004 and expect that the tax rate
should remain essentially constant.

Actual results could differ materially and will
depend on, among other things, the continuing growth
of our currently marketed products; developments with
competitive products; the timing and scope of regula-
tory approvals and the success of our new product

launches; foreign exchange rates; possible regulatory
actions; and the impact of state, federal, and foreign
government pricing and reimbursement measures. In
particular, as described below under Legal and Envi-
ronmental Matters, certain generic pharmaceutical
manufacturers have challenged our U.S. compound pat-
ent for Zyprexa. A trial court decision on the challenge
is expected during 2004. If the decision is unfavorable
and the generic companies launch generic olanzapine
prior to resolution of appeals, our ﬁ nancial results
would be very negatively affected. We undertake no
duty to update these forward-looking statements.

LEGAL AND ENVIRONMENTAL MATTERS

Three generic pharmaceutical manufacturers, Zenith
Goldline Pharmaceuticals, Inc. (Zenith), Dr. Reddy’s
Laboratories, Ltd. (Reddy), and Teva Pharmaceuticals,
have submitted abbreviated new drug applications
(ANDAs) seeking permission to market generic ver-
sions of Zyprexa in various dosage forms several
years prior to the expiration of our U.S. patents for the
product, alleging that our patents are invalid or not
infringed. We ﬁ led suits against the three companies in
U.S. District Court for the Southern District of Indiana
seeking a ruling that the challenges to our compound
patent (expiring in 2011) are without merit. The cases
have been consolidated. A trial before a district court
judge in Indianapolis began on January 26, 2004, and
is expected to conclude in February. A ruling from the
trial court is expected in the second or third quarter of
2004. Regardless of the trial court ruling, we anticipate
that appeals will follow. If we are unsuccessful at the
trial court level, we cannot predict whether any of the
generic companies would launch generic versions of
Zyprexa prior to a ﬁ nal resolution of any appeals. We
believe that the generic manufacturers’ claims are
without merit and we expect to prevail in this litiga-
tion. However, it is not possible to predict or determine
the outcome of this litigation and, accordingly, we can
provide no assurance that we will prevail. An unfavor-
able outcome would have a material adverse impact on
our consolidated results of operations, liquidity, and
ﬁ nancial position.

In October 2002, we were notiﬁ ed that Barr Labo-
ratories, Inc. (Barr), had submitted an ANDA to the U.S.
FDA seeking permission to market a generic version of
Evista several years prior to the expiration of our U.S.
patents covering the product, alleging that the patents
are invalid or not infringed. On November 26, 2002,
we ﬁ led suit against Barr in federal district court in
Indianapolis seeking a ruling that Barr’s challenges to
our patents claiming the method of use and pharma-
ceutical form (expiring from 2012 to 2017) are without
merit. In June 2003, Barr added a challenge to one of
our additional patents (expiring in 2017), claiming a

outcome of the legal and environmental matters de-
scribed above, we believe that, except as noted above in
connection with the discussion of the Zyprexa patent liti-
gation, the Evista patent litigation, and our marketing and
promotional practices, the resolution of all such matters
will not have a material adverse effect on our consoli-
dated ﬁ nancial position or liquidity but could possibly be
material to the consolidated results of operations in any
one accounting period.

PRIVATE SECURITIES LITIGATION REFORM ACT OF
1995—A CAUTION CONCERNING FORWARD-LOOKING
STATEMENTS

Under the safe harbor provisions of the Private Securi-
ties Litigation Reform Act of 1995, we caution investors
that any forward-looking statements or projections
made by us, including those made in this document, are
based on management’s expectations at the time they
are made, but they are subject to risks and uncertain-
ties that may cause actual results to differ materially
from those projected. Economic, competitive, govern-
mental, technological, legal, and other factors that
may affect our operations and prospects are discussed
above and in Exhibit 99 to our most recent report on
Forms 10-Q and 10-K ﬁ led with the Securities and Ex-
change Commission.

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component in the pharmaceutical form of Evista. This
patent has now been added to the lawsuit. The trial is
tentatively scheduled to begin in August 2005. While we
believe that Barr’s claims are without merit and expect
to prevail, it is not possible to predict or determine the
outcome of the litigation. Therefore, we can provide no
assurance that we will prevail. An unfavorable outcome
could have a material adverse impact on our consolidat-
ed results of operations, liquidity, and ﬁ nancial position.
In July 2002, we received a grand jury subpoena
for documents from the Ofﬁ ce of Consumer Litigation,
Department of Justice, related to our marketing and
promotional practices and physician communications
with respect to Evista. We received a second subpoena
seeking additional documents in July 2003. We continue
to cooperate with the government and have provided a
broad range of information concerning our U.S. market-
ing and promotional practices, including documents
relating to communications with physicians and the
remuneration of physician consultants and advisers. We
continue to review and enhance policies and procedures
designed to assure that our marketing and promotional
practices and physician communications comply with
promotional laws and regulations. In recent months,
several pharmaceutical companies have received
subpoenas from government agencies with respect to
a variety of products, including a number of neurosci-
ence products. It is possible that other Lilly products,
including Zyprexa, could become subject to investiga-
tion. It is possible that the outcome of the above matters
could include criminal charges and ﬁ nes and/or civil
penalties. We cannot predict or determine the outcome
of the above matters or reasonably estimate the amount
or range of amounts of any ﬁ nes or penalties that might
result from an adverse outcome. It is possible, however,
that an adverse outcome could have a material adverse
impact on our consolidated ﬁ nancial position, liquidity,
and results of operations.

We have been named as a defendant in numerous

product liability lawsuits, involving primarily diethyl-
stilbestrol (DES) and thimerosal. See Note 13 to the
consolidated ﬁ nancial statements for further informa-
tion on those matters.

Our worldwide operations are subject to complex
and changing environmental and health and safety laws
and regulations that will continue to require capital in-
vestment and operational expenses. We have also been
designated a potentially responsible party with respect
to fewer than 10 sites under the federal environmental
law commonly known as Superfund. For more informa-
tion on those matters, see Note 13 to the consolidated
ﬁ nancial statements.

While it is not possible to predict or determine the

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CONSOLIDATED STATEMENTS OF CASH FLOWS

Eli Lilly and Company and Subsidiaries
(Dollars in millions)

Year Ended December 31

2003

2002

2001

Cash Flows From Operating Activities
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 2,560.8

$ 2,707.9

$ 2,780.0

Adjustments To Reconcile Net Income to Cash Flows
From Operating Activities
Depreciation and amortization . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Change in deferred taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Acquired in-process research and development, net of tax . . . . .
Asset impairments, restructuring, and other

special charges, net of tax . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Changes in operating assets and liabilities

Receivables—(increase) decrease. . . . . . . . . . . . . . . . . . . . . . . .
Inventories—increase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other assets—increase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Accounts payable and other liabilities—increase (decrease) . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

548.5
130.9
—

261.7
61.0
3,562.9

(195.1)
(170.8)
(211.9)
661.6
83.8

493.0
346.5
54.6

—
10.8
3,612.8

(321.1)
(285.1)
(667.4)
(268.5)
(1,542.1)

454.9
273.8
123.8

78.9
27.6
3,739.0

167.5
(184.2)
(81.1)
20.4
(77.4)

Net Cash Provided by Operating Activities . . . . . . . . . . . . . . . . . . . .

3,646.7

2,070.7

3,661.6

Cash Flows From Investing Activities
Purchase of property and equipment . . . . . . . . . . . . . . . . . . . . . . . . . .
Disposals of property and equipment . . . . . . . . . . . . . . . . . . . . . . . . . .
Net change in short-term investments . . . . . . . . . . . . . . . . . . . . . . . . .
Proceeds from sales and maturities of noncurrent investments . . .
Purchase of noncurrent investments . . . . . . . . . . . . . . . . . . . . . . . . . .
Purchase of in-process research and development . . . . . . . . . . . . . .
Other, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net Cash Used in Investing Activities . . . . . . . . . . . . . . . . . . . . . . . . .

Cash Flows From Financing Activities
Dividends paid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Purchase of common stock and other capital transactions . . . . . . . .
Issuances of common stock under stock plans . . . . . . . . . . . . . . . . . .
Net change in short-term borrowings . . . . . . . . . . . . . . . . . . . . . . . . .
Proceeds from issuance of long-term debt . . . . . . . . . . . . . . . . . . . . .
Repayments of long-term debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net Cash Used for Financing Activities . . . . . . . . . . . . . . . . . . . . . . . .

(1,706.6)
61.2
774.0
6,762.4
(7,005.3)
—
(217.2)
(1,331.5)

(1,443.0)
(281.1)
103.1
(247.3)
830.0
(540.0)
(1,578.3)

(1,130.9)
36.8
(651.8)
4,777.9
(5,190.3)
(84.0)
(232.1)
(2,474.4)

(1,335.8)
(385.2)
64.6
(18.0)
1,259.6
(7.2)
(422.0)

(884.0)
31.6
(520.3)
3,708.7
(5,931.1)
(159.6)
(210.1)
(3,964.8)

(1,207.2)
(545.7)
109.5
102.0
901.3
(408.6)
(1,048.7)

Effect of exchange rate changes on cash . . . . . . . . . . . . . . . . . . . . . . .

73.5

69.3

(60.7)

Net increase (decrease) in cash and cash equivalents . . . . . . . . . . . .
Cash and cash equivalents at beginning of year . . . . . . . . . . . . . . . . .
Cash and cash equivalents at end of year . . . . . . . . . . . . . . . . . . . . .

810.4
1,945.9
$ 2,756.3

(756.4)
2,702.3
$ 1,945.9

(1,412.6)
4,114.9
$ 2,702.3

See notes to consolidated ﬁ nancial statements.

CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME

Eli Lilly and Company and Subsidiaries
(Dollars in millions)

Year Ended December 31

2003

2002

2001

Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other comprehensive income (loss)
Foreign currency translation gains (losses) . . . . . . . . . . . . . . . . . .
Net unrealized gains (losses) on securities. . . . . . . . . . . . . . . . . . .
Minimum pension liability adjustment . . . . . . . . . . . . . . . . . . . . . . .
Effective portion of cash ﬂ ow hedges. . . . . . . . . . . . . . . . . . . . . . . .
Other comprehensive income (loss) before income taxes . . . . . . . . .
Provision for income taxes related to
other comprehensive income (loss) items . . . . . . . . . . . . . . . . . . . .
Other comprehensive income (loss) (Note 14) . . . . . . . . . . . . . . . . . . .

$2,560.8

$2,707.9

$2,780.0

473.0
72.0
(9.8)
(2.1)
533.1

(22.4)
510.7

273.6
(67.4)
(4.6)
(217.9)
(16.3)

93.9
77.6

(83.8)
47.7
(95.6)
(42.0)
(173.7)

36.5
(137.2)

Comprehensive income. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$3,071.5

$2,785.5

$2,642.8

See notes to consolidated ﬁ nancial statements.

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SEGMENT INFORMATION

Eli Lilly and Company and Subsidiaries
(Dollars in millions)

We operate in one signiﬁ cant business segment—pharmaceutical products. Operations of the animal health busi-
ness segment are not material and share many of the same economic and operating characteristics as pharma-
ceutical products. Therefore, they are included with pharmaceutical products for purposes of segment reporting.

Year Ended December 31

2003

2002

2001

Net sales—to unafﬁ liated customers
Neurosciences. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Endocrinology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Oncology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Animal health . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cardiovascular . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Anti-infectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other pharmaceutical. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 5,554.8
3,926.7
1,039.8
726.6
669.3
489.9
175.4
$12,582.5

$ 4,668.3
3,444.6
893.1
693.1
624.9
577.4
176.1
$11,077.5

$ 5,328.2
3,103.5
739.1
686.1
593.4
749.5
342.7
$11,542.5

Geographic Information
Net sales—to unafﬁ liated customers1
United States . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Western Europe. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other foreign countries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 7,175.6
2,711.3
2,695.6
$12,582.5

$ 6,536.1
2,155.4
2,386.0
$11,077.5

$ 7,364.3
1,953.1
2,225.1
$11,542.5

Long-lived assets
United States . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Western Europe. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other foreign countries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 5,296.0
1,279.1
1,209.2
$ 7,784.3

$ 4,725.1
997.1
673.3
$ 6,395.5

$ 4,015.4
767.9
519.6
$ 5,302.9

1Net sales are attributed to the countries based on the location of the customer.

The largest category of products is the neurosciences group, which includes Zyprexa, Prozac, Strattera, and
Permax®. Endocrinology products consist primarily of Humulin, Humalog, Actos, Evista, Forteo, and Humatrope.
Oncology products consist primarily of Gemzar. Animal health products include Tylan®, Rumensin®, Coban®, and
other products for livestock and poultry. Cardiovascular products consist primarily of ReoPro and Xigris. Anti-in-
fectives include primarily Ceclor® and Vancocin®. The other pharmaceutical product group includes Cialis, Axid®,
and other miscellaneous pharmaceutical products and services.

Most of the pharmaceutical products are distributed through wholesalers that serve pharmacies, physicians and

other health care professionals, and hospitals. In 2003, our three largest wholesalers each accounted for between
15 percent and 16 percent of consolidated net sales. Further, they each accounted for between 9 percent and 15 percent
of accounts receivable as of December 31, 2003. Animal health products are sold primarily to wholesale distributors.
Our business segments are distinguished by the ultimate end user of the product: humans or animals. Per-
formance is evaluated based on proﬁ t or loss from operations before income taxes. The accounting policies of
the individual segments are substantially the same as those described in the summary of signiﬁ cant accounting
policies in Note 1 to the consolidated ﬁ nancial statements. Income before taxes for the animal health business was
approximately $204 million, $221 million, and $204 million in 2003, 2002, and 2001, respectively.

The assets of the animal health business are intermixed with those of the pharmaceutical products business

and are not separately determinable. Long-lived assets disclosed above consist of property and equipment and
certain sundry assets.

We are exposed to the risk of changes in social, political, and economic conditions inherent in foreign opera-
tions, and our results of operations and the value of our foreign assets are affected by ﬂ uctuations in foreign cur-
rency exchange rates.

SELECTED QUARTERLY DATA (UNAUDITED)

Eli Lilly and Company and Subsiaries
(Dollars in millions, except per-share data)
2003
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cost of sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Operating expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Asset impairments, restructuring, and
other special charges . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other—net. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Income before income taxes. . . . . . . . . . . . . . . . . . . . . . . . . . .
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Earnings per share—basic . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Earnings per share—diluted. . . . . . . . . . . . . . . . . . . . . . . . . . .

Fourth
$3,465.5
731.5
1,844.2

Third
$3,139.4
679.3
1,531.5

Second
$3,088.2
643.0
1,585.8

First
$2,889.4
621.3
1,444.1

28.3
(102.5)
964.0
747.2

.69

—
12.7
915.9
714.4

.66

—
(28.5)
887.9
692.2

.64

353.9
(23.8)
493.9
407.0

.38

Dividends paid per share. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

.335

Common stock closing prices
High. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Low . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

73.89
60.78

70.33
57.99

69.83
57.73

67.98
53.70

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2002
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cost of sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Operating expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Acquired in-process research and development . . . . . . . . . .
Other—net. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Income before income taxes. . . . . . . . . . . . . . . . . . . . . . . . . . .
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Fourth
$2,955.6
567.8
1,495.1
—
(51.3)
944.0
736.3

Third
$2,785.6
553.7
1,337.4
84.0
(52.3)
862.8
683.9

Second
$2,775.2
524.9
1,460.7
—
(54.6)
844.2
658.5

First
$2,561.1
530.1
1,280.1
—
(55.8)
806.7
629.2

Earnings per share—basic . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Earnings per share—diluted. . . . . . . . . . . . . . . . . . . . . . . . . . .

Dividends paid per share. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

.68

.31

.64

.63

.31

.61

.31

.58

.31

69.00
55.14

61.84
47.91

78.34
56.11

80.28
72.49

Our common stock is listed on the New York, London, and other stock exchanges.

SELECTED FINANCIAL DATA (UNAUDITED)

Eli Lilly and Company and Subsidiaries
(Dollars in millions, except per-share data)

2003

2002

2001

2000

1999

Operations
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $12,582.5
2,350.2
Research and development . . . . . . . . . . . . . . . . . . . .
6,970.6
Other costs and expenses. . . . . . . . . . . . . . . . . . . . . .
3,261.7
Income from continuing operations before taxes . .
Income taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
700.9
Income from:
Continuing operations . . . . . . . . . . . . . . . . . . . . . .
Discontinued operations . . . . . . . . . . . . . . . . . . . .
Net income. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Income from continuing operations
as a percent of sales . . . . . . . . . . . . . . . . . . . . . . . .
Per-share data—diluted

2,560.8
—
2,560.8

20.4%

$11,077.5
2,149.3
5,470.5
3,457.7
749.8

$11,542.5 $10,862.2 $10,002.9
1,783.6
4,973.9
3,245.4
698.7

2,235.1
5,800.5
3,506.9
726.9

2,018.5
4,985.0
3,858.7
800.9

2,707.9
—
2,707.9

2,780.0
—
2,780.0

3,057.8
—
3,057.8

2,546.7
174.3
2,721.0

24.4%

24.1%

28.2%

25.5%

Income from:
Continuing operations . . . . . . . . . . . . . . . . . . . . $ 2.37
—
Discontinued operations . . . . . . . . . . . . . . . . . .
2.37
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Dividends declared per share . . . . . . . . . . . . . . . . . .
1.36
Weighted-average number of shares
outstanding—diluted (thousands). . . . . . . . . . . . . 1,082,230

$ 2.50
—
2.50
1.27

$ 2.55 $ 2.79
—
2.79
1.06

—
2.55
1.15

$ 2.30
.16
2.46
.95

1,085,088

1,090,793

1,097,725

1,106,055

Financial Position
Current assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 8,758.7
5,550.6
Current liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Property and equipment—net . . . . . . . . . . . . . . . . . .
6,539.0
Total assets. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21,678.1
4,687.8
Long-term debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
9,764.8
Shareholders’ equity . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 7,804.1 $ 6,938.9 $ 7,943.0 $ 7,055.5
3,935.4
3,981.5
12,825.2
2,811.9
5,013.0

5,203.0
4,532.4
16,434.1
3,132.1
7,104.0

4,960.7
4,176.6
14,690.8
2,633.7
6,046.9

5,063.5
5,293.0
19,042.0
4,358.2
8,273.6

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Supplementary Data1
Return on shareholders’ equity . . . . . . . . . . . . . . . . .
Return on assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Capital expenditures . . . . . . . . . . . . . . . . . . . . . . . . . . $ 1,706.6
548.5
Depreciation and amortization . . . . . . . . . . . . . . . . . .
Effective tax rate . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Number of employees . . . . . . . . . . . . . . . . . . . . . . . . .
Number of shareholders of record . . . . . . . . . . . . . .

46,100
54,600

28.4%
12.7%

21.5%

35.2%
15.2%

42.3%
17.8%

55.3%
22.9%

53.9%
21.3%

$ 1,130.9 $ 884.0 $ 677.9 $ 528.3
439.7
21.5%

20.8%

20.7%

21.7%

435.8

454.9

493.0

43,700
56,200

41,100
57,700

35,700
59,200

31,300
62,300

1 All supplementary ﬁ nancial data have been computed using income from continuing operations except for capital
expenditures and depreciation and amortization, which include amounts from discontinued operations. The num-
ber of employees reﬂ ects continuing operations, including controlled joint ventures.

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NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

Eli Lilly and Company and Subsidiaries
(Dollars in millions, except per-share data)

Note 1: Summary of Signiﬁ cant Accounting Policies

Basis of presentation: The accounts of all wholly owned and majority-owned subsidiaries are included in the
consolidated ﬁ nancial statements. Where our ownership of consolidated subsidiaries is less than 100 percent, the
outside shareholders’ interests are reﬂ ected in other noncurrent liabilities. All intercompany balances and trans-
actions have been eliminated.

The preparation of ﬁ nancial statements in conformity with generally accepted accounting principles requires

management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues,
expenses, and related disclosures at the date of the ﬁ nancial statements and during the reporting period. Actual
results could differ from those estimates.

All per-share amounts, unless otherwise noted in the footnotes, are presented on a diluted basis, that is,

based on the weighted-average number of outstanding common shares and the effect of all potentially dilutive
common shares (primarily unexercised stock options).

Cash equivalents: We consider all highly liquid investments, generally with a maturity of three months or less,

to be cash equivalents. The cost of these investments approximates fair value. If items meeting this deﬁ nition are
part of a larger investment pool, they are classiﬁ ed consistent with the classiﬁ cation of the pool.

Inventories: We state all inventories at the lower of cost or market. We use the last-in, ﬁ rst-out (LIFO) method

for substantially all our inventories located in the continental United States, or approximately 40 percent of our
total inventories. Other inventories are valued by the ﬁ rst-in, ﬁ rst-out (FIFO) method. FIFO cost approximates cur-
rent replacement cost. Inventories at December 31 consisted of the following:

Finished products . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Work in process . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Raw materials and supplies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Reduction to LIFO cost . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 542.1
1,169.0
315.9
2,027.0
(64.0)
$1,963.0

$ 482.9
816.3
242.7
1,541.9
(46.5)
$1,495.4

2003

2002

Investments: Substantially all debt and marketable equity securities are classiﬁ ed as available-for-sale.
Available-for-sale securities are carried at fair value with the unrealized gains and losses, net of tax, reported in
other comprehensive income. Unrealized losses considered to be other-than-temporary are recognized in earn-
ings currently. Factors we consider in making this evaluation include company-speciﬁ c drivers of the decrease in
stock price, status of projects in development, near-term prospects of the issuer, the length of time the value has
been depressed, and the ﬁ nancial condition of the industry. Realized gains and losses on sales of available-for-
sale securities are computed based upon speciﬁ c identiﬁ cation of the initial cost adjusted for any other-than-tem-
porary declines in fair value. Investments in companies over which we have signiﬁ cant inﬂ uence but not a con-
trolling interest are accounted for using the equity method with our share of earnings or losses reported in other
income. We own no investments that are considered to be trading securities.

Derivative ﬁ nancial instruments: Our derivative activities are initiated within the guidelines of documented

corporate risk-management policies and do not create additional risk because gains and losses on derivative con-
tracts offset losses and gains on the assets, liabilities, and transactions being hedged. As derivative contracts are
initiated, we designate the instruments individually as either a fair value hedge or a cash ﬂ ow hedge. Management
reviews the correlation and effectiveness of our derivatives on a quarterly basis.

For derivative contracts that are designated and qualify as fair value hedges, the derivative instrument is
marked to market with gains and losses recognized currently in income to offset the respective losses and gains
recognized on the underlying exposure. For derivative contracts that are designated and qualify as cash ﬂ ow hedg-
es, the effective portion of gains and losses on these contracts is reported as a component of other comprehensive
income and reclassiﬁ ed into earnings in the same period the hedged transaction affects earnings. Hedge inef-
fectiveness is immediately recognized in earnings. Derivative contracts that are not designated as hedging instru-
ments are recorded at fair value with the gain or loss recognized in current earnings during the period of change.

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We enter into foreign currency forward and option contracts to reduce the effect of ﬂ uctuating currency ex-
change rates (principally the Japanese yen and the euro). Generally, foreign currency derivatives used for hedging
are put in place using the same or like currencies and duration as the underlying exposures. Forward contracts
are principally used to manage exposures arising from subsidiary trade and loan payables and receivables denom-
inated in foreign currency. These contracts are recorded at fair value with the gain or loss recognized in current
earnings. The purchased option contracts are used to hedge anticipated foreign currency transactions, primarily
intercompany inventory activities expected to occur within the next year. These contracts are designated as cash
ﬂ ow hedges of those future transactions and the impact on earnings is included in cost of sales. We may enter into
foreign currency forward contracts and currency swaps as fair value hedges of ﬁ rm commitments. Forward and
option contracts generally have maturities not exceeding 12 months.

In the normal course of business, our operations are exposed to ﬂ uctuations in interest rates. These ﬂ uc-

tuations can vary the costs of ﬁ nancing, investing, and operating. We address a portion of these risks through a
controlled program of risk management that includes the use of derivative ﬁ nancial instruments. The objective of
controlling these risks is to limit the impact of ﬂ uctuations in interest rates on earnings. Our primary interest rate
risk exposure results from changes in short-term U.S. dollar interest rates. In an effort to manage interest rate
exposures, we strive to achieve an acceptable balance between ﬁ xed and ﬂ oating rate debt and investment posi-
tions and may enter into interest rate swaps or collars to help maintain that balance. Interest rate swaps or collars
that convert our ﬁ xed rate debt or investments to a ﬂ oating rate are designated as fair value hedges of the under-
lying instruments. Interest rate swaps or collars that convert ﬂ oating rate debt or investments to a ﬁ xed rate are
designated as cash ﬂ ow hedges. Interest expense on the debt is adjusted to include the payments made or received
under the swap agreements.

Goodwill and other intangibles: Other intangibles with ﬁ nite lives arising from acquisitions and research al-
liances are amortized over their estimated useful lives, ranging from 5-10 years, using the straight-line method.
Beginning with our adoption of Statement of Financial Accounting Standards (SFAS) 142, Goodwill and Other Intan-
gible Assets, on January 1, 2002, goodwill is no longer amortized. Goodwill and other intangibles are reviewed to
assess recoverability at least annually and when certain impairment indicators are present. Unamortized goodwill
and other intangibles with ﬁ nite lives were $92.2 million and $94.7 million, respectively, at December 31, 2003 and
2002, and were included in sundry assets in the consolidated balance sheets. We currently have no other intangible
assets with indeﬁ nite lives. No material impairments occurred with respect to the carrying value of our goodwill or
other intangible assets in 2003, 2002, or 2001. Amortization of goodwill in 2001 was negligible.

Property and equipment: Property and equipment is stated on the basis of cost. Provisions for depreciation
of buildings and equipment are computed generally by the straight-line method at rates based on their estimated
useful lives (generally 12 to 50 years for buildings and 3 to 18 years for equipment).

At December 31, property and equipment consisted of the following:

Land . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Buildings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Equipment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Construction in progress . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Less allowances for depreciation . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 124.8
3,134.7
5,305.8
2,502.7
11,068.0
4,529.0
$ 6,539.0

$ 111.0
2,871.7
5,148.4
1,415.0
9,546.1
4,253.1
$5,293.0

2003

2002

Depreciation expense for 2003, 2002, and 2001 was $469.3 million, $437.8 million, and $414.9 million, respec-

tively. Approximately $61.0 million, $60.3 million, and $61.5 million of interest costs were capitalized as part of
property and equipment in 2003, 2002, and 2001, respectively. Total rental expense for all leases, including con-
tingent rentals (not material), amounted to approximately $268.5 million, $240.8 million, and $207.1 million for
2003, 2002, and 2001, respectively. Capital leases included in property and equipment in the consolidated balance
sheets, capital lease obligations entered into, and future minimum rental commitments are not material.

Revenue recognition: We recognize revenue from sales of products at the time title of goods passes to the

buyer and the buyer assumes the risks and rewards of ownership. This is generally at the time products are
shipped to the customer. Provisions for discounts and rebates to customers are established in the same period the
related sales are recorded and are included in other current liabilities. Revenue from copromotion services (pri-
marily Actos) is based upon net sales reported by our copromotion partner and, if applicable, the number of sales
calls we perform. We immediately recognize the full amount of milestone payments due us upon the achievement

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of the milestone event if the event is substantive, objectively determinable, and represents an important point in
the development life cycle of the pharmaceutical product. Milestone payments earned by us are generally recorded
in other income-net. Initial fees we receive from the partnering of our compounds under development are amor-
tized through the expected product approval date. Initial fees received from out-licensing agreements that include
both the sale of marketing rights to our commercialized products and a related commitment to supply the products
are generally recognized as net sales over the term of the supply agreement.

Research and development: We recognize as incurred the cost of directly acquiring assets to be used in the

research and development process that have not yet received regulatory approval for marketing and for which no
alternative future use has been identiﬁ ed. If the product has obtained regulatory approval, we generally capitalize
the milestones paid and amortize them over the period beneﬁ ted. Milestones paid prior to regulatory approval of
the product are generally expensed when the event requiring payment of the milestone occurs.

Income taxes: Deferred taxes are recognized for the future tax effects of temporary differences between
ﬁ nancial and income tax reporting based on enacted tax laws and rates. Federal income taxes are provided on the
portion of the income of foreign subsidiaries that is expected to be remitted to the United States and be taxable.

Earnings per share: We calculate basic earnings per share based on the weighted-average number of outstand-
ing common shares and incremental shares. We calculate diluted earnings per share based on the weighted-average
number of outstanding common shares plus the effect of dilutive stock options and other incremental shares.

Stock-based compensation: As discussed further in Note 7, we have elected to follow Accounting Principles
Board (APB) Opinion 25, Accounting for Stock Issued to Employees, and related interpretations in accounting for
our stock options and performance awards. Under APB 25, because the exercise price of our employee stock
options equals the market price of the underlying stock on the date of grant, no compensation expense is recog-
nized. However, SFAS 123, Accounting for Stock-Based Compensation, as amended by SFAS 148, Accounting for
Stock-Based Compensation-Transition and Disclosure, requires us to present pro forma information as if we had
accounted for our employee stock options and performance awards under the fair value method of that statement.
For purposes of pro forma disclosure, the estimated fair value of the options and performance awards at the date
of the grant is amortized to expense over the vesting period. The following table illustrates the effect on net income
and earnings per share if we had applied the fair value recognition provisions of SFAS 123 to stock-based employee
compensation.

Net income, as reported . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$2,560.8

$2,707.9

$2,780.0

2003

2002

2001

Add: Compensation expense for stock-based
performance awards included in reported net income,
net of related tax effects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Deduct: Total stock-based employee compensation
expense determined under fair-value-based method

—

5.5

for all awards, net of related tax effects . . . . . . . . . . . . . . . . . . . . .
Pro forma net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

(220.8)
$2,340.0

(322.1)
$2,385.8

(215.9)
$2,569.6

Earnings per share:
Basic, as reported. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Basic, pro forma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Diluted, as reported . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Diluted, pro forma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$2.38
$2.17

$2.37
$2.16

$2.51
$2.22

$2.50
$2.20

$2.58
$2.38

$2.55
$2.36

Note 2: Implementation of New Financial Accounting Pronouncements

In 2001, the Financial Accounting Standards Board (FASB) issued SFAS 143, Accounting for Asset Retirement Obli-
gations. SFAS 143 requires companies to record the fair value of a liability for an asset retirement obligation in the
period in which it is incurred, which is adjusted to its present value each subsequent period. In addition, companies
must capitalize a corresponding amount by increasing the carrying amount of the related long-lived asset, which
is depreciated over the useful life of the related long-lived asset. The adoption of SFAS 143 on January 1, 2003, had
no impact on our consolidated ﬁ nancial position or results of operations.

In 2002, the FASB issued SFAS 145, Rescission of FASB Statements No. 4, 44, and 64, Amendment of FASB State-

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ment No. 13, and Technical Corrections. SFAS 145 eliminates the classiﬁ cation of debt extinguishments as extraor-
dinary items. The adoption of this statement on January 1, 2003, resulted in the reclassiﬁ cation of the extraordinary
item resulting from debt extinguishment in 2001 to interest expense. The adoption had no impact on our net income.

In 2002, the FASB issued SFAS 146, Accounting for Costs Associated with Exit or Disposal Activities. SFAS 146

requires that a liability for a cost associated with an exit or disposal activity be recognized when the liability is
incurred. Severance pay under SFAS 146, in many cases, would be recognized over the remaining service period
rather than at the time the plan is communicated. The provisions of SFAS 146 are effective for exit or disposal
activities that are initiated after December 31, 2002. We adopted SFAS 146 for any actions initiated after January 1,
2003, and any future exit costs or disposal activities will be subject to this statement.

In 2002, the FASB issued FASB Interpretation (FIN) 45, Guarantor’s Accounting and Disclosure Requirements
for Guarantees, Including Indirect Guarantees of Indebtedness of Others. FIN 45 requires an issuer of a guarantee
to recognize an initial liability for the fair value of the obligations covered by the guarantee. FIN 45 also addresses
the disclosures required by a guarantor in interim and annual ﬁ nancial statements regarding obligations under
guarantees. We have adopted the requirement for recognition of liabilities for the fair value of guaranteed obliga-
tions prospectively for guarantees entered into after January 1, 2003. We adopted the disclosure provisions as of
December 31, 2002.

In 2003, the FASB issued FIN 46, Consolidation of Variable Interest Entities. FIN 46 deﬁ nes a variable interest

entity (VIE) as a corporation, partnership, trust, or any other legal structure that does not have equity investors
with a controlling ﬁ nancial interest or has equity investors that do not provide sufﬁ cient ﬁ nancial resources for
the entity to support its activities. FIN 46 requires consolidation of a VIE by the primary beneﬁ ciary of the assets,
liabilities, and results of activities. FIN 46 also requires certain disclosures by all holders of a signiﬁ cant variable
interest in a VIE that are not the primary beneﬁ ciary. We do not have any material investments in variable interest
entities; therefore, the adoption of this interpretation in the ﬁ rst quarter of 2004 is not expected to have a material
impact on our consolidated ﬁ nancial position or results of operations.

In 2003, the FASB issued SFAS 150, Accounting for Certain Financial Instruments with Characteristics of both
Liabilities and Equity. SFAS 150 establishes standards for how an issuer classiﬁ es and measures certain ﬁ nancial
instruments with characteristics of both liabilities and equity. Financial instruments within the scope of SFAS 150
will now be required to be classiﬁ ed as a liability. This statement also requires enhanced disclosures regarding
alternative methods of settling the instruments and the capital structure of entities. SFAS 150 is effective for all
ﬁ nancial instruments entered into or modiﬁ ed after May 31, 2003, and otherwise is effective at the beginning of the
ﬁ rst interim period beginning after June 15, 2003. The adoption of this statement had no impact on our consoli-
dated ﬁ nancial position or results of operations.

On January 12, 2004, the FASB issued FASB Staff Position (FSP) FAS106-1 regarding the accounting for the
effects of the Medicare Prescription Drug, Improvement and Modernization Act of 2003 (MMA). The FSP allows
companies an opportunity to assess the effect of MMA on their retirement-related beneﬁ t costs and obligations
and reﬂ ect the effects in the 2003 ﬁ nancial statements, pursuant to SFAS 106, Employer’s Accounting for Postre-
tirement Beneﬁ ts Other Than Pensions. Companies are also allowed to defer accounting for the effects of MMA
until authoritative guidance is issued. We have elected to defer accounting for the effects of MMA, in accordance
with the FSP. As a result, the accumulated postretirement beneﬁ t obligation and net periodic postretirement ben-
eﬁ t cost discussed in Note 12 do not reﬂ ect the effects of MMA on the plan. Speciﬁ c authoritative guidance on the
accounting for the federal subsidy, one of the provisions of MMA, is pending and that guidance, when issued, could
require us to change previously reported information.

Note 3: Acquisition, Collaborations, and Disposition

In November 2003, we announced a merger agreement with Applied Molecular Evolution, Inc. (AME). Shareholders
of AME will vote upon a proposal to adopt the merger agreement on February 11, 2004. Under terms of the agree-
ment, AME shareholders will receive $18 for each outstanding AME share at closing. AME shareholders may elect
to receive the $18 in cash or shares of Lilly common stock based on the closing price of Lilly stock on the closing
date, subject to proration such that the total purchase price paid by Lilly is 80 percent stock and 20 percent cash.
The purchase price of the acquisition, including transaction costs, is estimated to be approximately $400 million,
net of cash acquired. The merger is expected to close in the ﬁ rst quarter of 2004. While the allocation of the pur-
chase price will not be completed until after the effective date of the merger, we anticipate that a signiﬁ cant portion
of the purchase price will be allocated to acquired in-process research and development and charged to expense
in the ﬁ rst quarter of 2004.

In September 2002, we entered into a collaboration arrangement with Amylin Pharmaceuticals, Inc. (Amylin),

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to jointly develop and commercialize Amylin’s synthetic exendin-4 compound, a potential new treatment for type
2 diabetes. In 2001, we entered into collaboration arrangements with three companies. In August, we licensed
from Isis Pharmaceuticals, Inc. (Isis), Afﬁ nitak™, a non-small-cell lung cancer drug candidate and entered into
an agreement regarding an ongoing research collaboration. In September, we entered into a collaboration with
Bioprojet, Société Civile de Recherche, to jointly develop and commercialize a vasopeptidase inhibitor (fasidotril)
for hypertension and chronic heart failure. In October, we entered into a collaboration with 3M Company to jointly
develop and commercialize an immune response modiﬁ er (resiquimod) for various forms of herpes. The ongoing
activity with respect to each of these agreements is not material to our research and development expenses.

At the inception of these collaborations, these compounds were in the development phase and no alternative
future uses were identiﬁ ed. As with many development phase compounds, launch of the products, if approved, was
not expected in the near term. Our charge for acquired in-process research and development expense related to
these arrangements totaled $84.0 million and $190.5 million in 2002 and 2001, respectively. See Note 4 for further
discussion of 2003 developments regarding the Isis agreements. In 2003, based upon recent clinical results of
resiquimod and fasidotril and other opportunities we have in our product pipeline, the collaboration agreements
between the parties were terminated.

In conjunction with the collaboration arrangement with Amylin, we also entered into a loan agreement. Fol-

lowing the successful completion of the ongoing clinical trials and contingent upon certain other events, we have
agreed to loan Amylin up to $110 million during the development period of the product, repayable in cash or Amylin
stock at our option. As of December 31, 2003, no loans to Amylin were outstanding.

Note 4: Asset Impairments, Restructuring, and Other Special Charges

In December 2002, we initiated a plan of eliminating approximately 700 positions worldwide in order to streamline
our infrastructure. While a substantial majority of affected employees were successfully placed in other positions
in the company, severance expenses were incurred in the ﬁ rst quarter of 2003 for those employees who elected a
severance package. The restructuring and other special charges incurred in the ﬁ rst quarter were $52.5 million,
consisting primarily of voluntary severance expenses, which have been included in asset impairments, restructur-
ing, and other special charges in our consolidated statement of income. Approximately $40.0 million of this charge
was expended during 2003 with substantially all the remainder to be expended during the ﬁ rst quarter of 2004.

In addition, as part of our previously disclosed ongoing strategic review, management approved global manu-
facturing strategies across our product portfolio during 2003 to improve plant performance and efﬁ ciency, includ-
ing the outsourcing of production of certain anti-infective products. These decisions resulted in the impairment of
certain assets, primarily manufacturing assets in the U.S. This review did not result in any closure of facilities, but
certain assets located at various manufacturing sites were affected. We have ceased using these assets and sub-
stantially all these assets have been disposed of or destruction commenced in 2003. The impairment charges were
necessary to adjust the carrying value of these assets to zero. These asset impairment charges totaled $142.9 mil-
lion, of which $114.6 million was incurred in the ﬁ rst quarter of 2003 with the remaining $28.3 million incurred in
the fourth quarter of 2003, and are included in asset impairments, restructuring, and other special charges in our
consolidated statement of income.

In conjunction with the Isis agreement discussed in Note 3, we purchased approximately 4.2 million shares of

Isis common stock with a cost basis of approximately $68.0 million and we committed to loan Isis $100 million over
the four-year term of the research agreement. The Isis loan is repayable at the end of the research agreement
term in cash or Isis stock, at Isis’s option, using a conversion price of $40 per share. In addition, we committed to
loan Isis $21.2 million for the building of a manufacturing suite for Afﬁ nitak. On March 17, 2003, we announced,
along with Isis, the results of the Phase III trial that evaluated Afﬁ nitak when combined with chemotherapy in
patients with advanced non-small-cell lung cancer. No difference was observed in the overall survival of the two
groups. Due to this announcement and the decline in Isis’s stock price that occurred in the previous 12 months, we
concluded that our investment in Isis common stock was other-than-temporarily impaired as deﬁ ned by gener-
ally accepted accounting principles. For the same reasons, it was probable that the value of the consideration that
we will be eligible to receive from Isis pursuant to the terms of the loan agreements will be less than the carry-
ing amount of the loans. Therefore, in the ﬁ rst quarter of 2003, we recognized an impairment in our investment in
Isis common stock of $55.0 million and a reserve related to the loans of $92.9 million. In addition, we recognized a
charge of $38.9 million for contractual obligations related to Afﬁ nitak. The primary portion of this charge resulted
from our supply agreement with Isis. The supply agreement obligated us to pay certain costs associated with work-
in-process and raw materials and other costs that were triggered when we canceled our order of Afﬁ nitak. The re-
maining portion of the charge resulted from our contractual obligations related to the conduct of Afﬁ nitak clinical

trials. As of December 31, 2003, approximately $2.5 million remained related to the original $38.9 million charge.
The remaining cash payments associated with the Afﬁ nitak trials are expected to be made through mid-2004. The
stock and loan impairments and other special charges incurred in the ﬁ rst quarter related to this relationship
totaled $186.8 million and have been included in the asset impairments, restructuring, and other special charges
category in our consolidated statement of income.

As a result of a strategic review of our global manufacturing operations, we recognized asset impairment and

other site charges totaling $121.4 million in the third quarter of 2001. The charges principally consist of impair-
ments of facilities and equipment that were substantially disposed of in 2002, termination of third-party manu-
facturing arrangements, and a plant closure in Taiwan. The impairment charges were necessary to adjust the
carrying value of certain manufacturing assets to fair value. The fair value of the assets was estimated based upon
anticipated future cash ﬂ ows, discounted at a rate commensurate with the risk involved. Approximately $18 million
of this charge was for severance-related costs, which were fully expended during 2002.

Note 5: Financial Instruments and Investments

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Financial instruments that potentially subject us to credit risk consist principally of trade receivables and interest-
bearing investments. Wholesale distributors of life-sciences products and managed care organizations account
for a substantial portion of trade receivables; collateral is generally not required. The risk associated with this
concentration is mitigated by our ongoing credit review procedures. We place substantially all our interest-bearing
investments with major ﬁ nancial institutions, in U.S. government securities, or with top-rated corporate issuers.
In accordance with documented corporate policies, we limit the amount of credit exposure to any one ﬁ nancial
institution. We are exposed to credit-related losses in the event of nonperformance by counterparties to ﬁ nancial
instruments but do not expect any counterparties to fail to meet their obligations given their high credit ratings.

Fair Value of Financial Instruments

A summary of our outstanding ﬁ nancial instruments and other investments at December 31 follows:

Short-term investments
Debt securities . . . . . . . . . . . . . . . . . . . . . . . . . . .

Noncurrent investments
Marketable equity . . . . . . . . . . . . . . . . . . . . . . . . .
Debt securities . . . . . . . . . . . . . . . . . . . . . . . . . . .
Equity method and other investments . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Carrying Amount

Fair Value

Carrying Amount

Fair Value

2003

2002

$ 957.0

$ 1,708.8

$ 105.5
3,173.1
96.0
$3,374.6

$ 105.5
3,173.1
N/A

$ 85.9
2,458.6
605.9
$ 3,150.4

$ 85.9
2,458.6
N/A

Long-term debt, including current portion. . . . . . .

$4,867.5

$5,107.8

$4,643.6

$4,886.7

We determine fair values based on quoted market values where available or discounted cash ﬂ ow analyses
(principally long-term debt). The fair value of equity method investments is not readily available and disclosure
is not required. The fair value and carrying amount of risk-management instruments in the aggregate were not
material at December 31, 2003 and 2002. Approximately $3.6 billion of our investments in debt securities mature
within ﬁ ve years.

A summary of the unrealized gains and losses (pretax) of our available-for-sale securities in other compre-

hensive income at December 31 follows:

Unrealized gross gains . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Unrealized gross losses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2003

$72.3
10.6

2002

$77.4
87.7

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The net adjustment to unrealized gains and losses (net of tax) on available-for-sale securities increased (de-

creased) other comprehensive income by $45.4 million, ($45.0) million, and $34.3 million in 2003, 2002, and 2001,
respectively. Activity related to our available-for-sale investment portfolio was as follows:

Proceeds from sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Realized gross gains on sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Realized gross losses on sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$4,903.7
72.1
26.4

$3,724.2
57.0
35.2

$1,826.3
14.1
0.1

2003

2002

2001

During the years ended December 31, 2003 and 2002, net losses related to ineffectiveness and net losses re-
lated to the portion of fair value and cash ﬂ ow hedging instruments excluded from the assessment of effectiveness
were not material.

We expect to reclassify an estimated $53.9 million of pretax net losses on cash ﬂ ow hedges of anticipated for-

eign currency transactions and the variability in expected future interest payments on ﬂ oating rate debt from accu-
mulated other comprehensive loss to earnings during 2004. This assumes that short-term interest rates remain
unchanged from the prevailing rates at December 31, 2003.

Note 6: Borrowings

Long-term debt at December 31 consisted of the following:

2003

2002

4.50 to 7.13 percent notes (due 2012-2036) . . . . . . . . . . . . . . . . . . . . . .
2.90 to 8.38 percent notes (due 2003-2008) . . . . . . . . . . . . . . . . . . . . .
Floating rate bonds (due 2008-2037). . . . . . . . . . . . . . . . . . . . . . . . . . .
Private placement bonds (due 2007-2008) . . . . . . . . . . . . . . . . . . . . . .
Floating rate capital securities (due 2029) . . . . . . . . . . . . . . . . . . . . . .
8.38 percent eurodollar bonds (due 2005) . . . . . . . . . . . . . . . . . . . . . .
Resettable coupon capital securities (due 2029) . . . . . . . . . . . . . . . . .
6.55 percent ESOP debentures (due 2017) . . . . . . . . . . . . . . . . . . . . . .
Other, including capitalized leases . . . . . . . . . . . . . . . . . . . . . . . . . . . .
SFAS 133 fair value adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Less current portion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$1,487.4
811.4
417.8
810.5
525.0
150.0
300.0
94.6
130.3
140.5
4,867.5
179.7
$4,687.8

$ 1,287.4
711.4
666.6
542.8
525.0
150.0
300.0
95.6
130.8
234.0
4,643.6
285.4
$4,358.2

In March 2003, we issued $300.0 million of 2.9 percent 5-year notes and $200.0 million of 4.5 percent 15-year
notes. In July 2002 and May 2001, we issued $150.0 million and $250.0 million, respectively, of ﬂ oating rate bonds
that mature in 2037. The variable interest rate on these bonds is at LIBOR (1.27 percent at December 31, 2003) and
beginning May 15, 2004, will adjust every six months to reﬂ ect our six-month credit spread. The interest accumu-
lates over the life of the bonds and is payable upon maturity. We have an option to begin periodic interest payments
any time after May 15, 2004. At the time of option exercise, we would owe all previously accrued interest on the
bonds. Additionally, in July 2003 and July 2002, respectively, we executed a $330.0 million and $542.8 million private
placement note with a ﬁ nancial institution. Principal and interest are due semiannually over the ﬁ ve-year terms of
each of these notes. In conjunction with these notes, we entered into interest rate swap agreements with the same
ﬁ nancial institution, which converts the ﬁ xed rate into a variable rate of interest at essentially LIBOR over the term
of the notes. In March 2002, we issued $500.0 million of 10-year 6.0 percent notes. In addition, in 2001, we issued
$400.0 million of 5.5 percent notes due July 2006 and $249.5 million of ﬂ oating rate bonds due October 2008.

The ﬂ oating rate capital securities and the resettable coupon capital securities are subordinated to the notes,

bonds, and debentures listed above. The ﬂ oating rate capital securities pay cumulative interest at an annual rate
equal to LIBOR plus a predetermined spread, reset quarterly. The rates at December 31, 2003 and 2002, were 2.37
percent and 2.86 percent, respectively. The securities may be redeemed any time on or after August 5, 2004, for a
deﬁ ned redemption price. The resettable coupon capital securities pay cumulative interest at an annual rate of 7.72
percent until August 1, 2004. At this date and every ﬁ fth anniversary thereafter, the interest rate will be reset equal
to the weekly average interest rate of U.S. treasury securities having an index maturity of ﬁ ve years for the week
immediately preceding the reset date plus a predetermined spread. The securities may be redeemed on August 1,

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2004, and anytime thereafter for a deﬁ ned redemption price.

The 6.55 percent Employee Stock Ownership Plan (ESOP) debentures are obligations of the ESOP but are
shown on the consolidated balance sheet because we guarantee them. The principal and interest on the debt are
funded by contributions from us and by dividends received on certain shares held by the ESOP. Because of the am-
ortizing feature of the ESOP debt, bondholders will receive both interest and principal payments each quarter.

In 2001, we repurchased $188.6 million of 8.38 percent notes due in 2006, $14.0 million of 6.77 percent notes
due in 2036, and $198.6 million of 7.13 percent notes due in 2025. As a result of this early extinguishment of debt,
we recognized a charge of $45.2 million. As a result of our adoption of SFAS 145 in 2003 (see Note 2), this charge
was reclassiﬁ ed from an extraordinary charge to interest expense. In 2003, we repurchased $257.1 million of ﬂ oat-
ing rate debt securities due in 2008.

The aggregate amounts of maturities on long-term debt for the next ﬁ ve years are as follows: 2004, $179.7 mil-

lion; 2005, $360.3 million; 2006, $719.4 million; 2007, $207.4 million; and 2008, $389.6 million.

At December 31, 2003 and 2002, short-term borrowings included $16.8 million and $260.0 million, respec-
tively, of notes payable to banks. Included in short-term borrowings in 2002 are $250.0 million of 4.23 percent
one-year resettable notes issued in March 2001. These notes were repaid in 2003. At December 31, 2003, unused
committed lines of credit totaled approximately $1.24 billion. Compensating balances and commitment fees are not
material, and there are no conditions that are probable of occurring under which the lines may be withdrawn.

We have converted substantially all ﬁ xed rate debt to ﬂ oating rates through the use of interest rate swaps.
The weighted-average effective borrowing rate based on debt obligations and interest rates at December 31, 2003
and 2002, including the effects of interest rate swaps for hedged debt obligations, was 2.7 percent and 3.5 percent,
respectively.

Cash payments of interest on borrowings totaled $44.7 million, $54.6 million, and $171.6 million in 2003, 2002,

and 2001, respectively.

In accordance with the requirements of SFAS 133, the portion of our ﬁ xed-rate debt obligations that is hedged
is reﬂ ected in the consolidated balance sheet as an amount equal to the sum of the debt’s carrying value plus the
fair value adjustment representing changes in fair value of the hedged debt attributable to movements in market
interest rates subsequent to the inception of the hedge.

Note 7: Stock Plans

Stock options are granted to employees at exercise prices equal to the fair market value of the company’s stock
at the dates of grant. Generally, options vest 100 percent 3 years from the grant date and have a term of 10 years.
Performance awards are granted to ofﬁ cers and key employees and are payable in shares of our common stock.
The number of performance award shares actually issued, if any, varies depending upon the achievement of cer-
tain earnings-per-share targets. In general, performance awards vest 100 percent at the end of the second ﬁ scal
year following the grant date. No performance awards were granted in 2002.

We issued a grant under the GlobalShares program in 2001. Essentially all employees were given an option to
buy 125 shares of our stock at a price equal to the fair market value of our stock on the date of the grant. Options to
purchase approximately 4.3 million shares were granted as part of the program in 2001. Individual grants gener-
ally become exercisable on or after the third anniversary of the grant date and have a term of 10 years.

We also issued a special stock option grant in 2001 to global management and all employees in the U.S. and

Puerto Rico. This option grant was designed to retain and motivate employees affected by the compensation
changes due to the Prozac patent expiration. Options to purchase approximately 10.0 million shares were granted
as part of this program at a price equal to the fair market value on the date of the grant. Approximately 7.3 million
of these options vested in 2002 with the remainder vesting in 2003.

We have elected to follow APB Opinion 25 and related interpretations in accounting for our stock options and
performance awards. See Note 1 for a calculation of our net income and earnings per share under the fair value
method pursuant to SFAS 123.

The weighted-average per-share fair values of the individual options and performance awards granted during

2003, 2002, and 2001 were as follows on the date of grant:

Employee stock options . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Performance awards. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$20.59
63.51

$25.98
N/A

2003

2002

2001

$26.59
78.86

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The fair values of the options calculated in accordance with SFAS 123 were determined using a Black-Scholes

option-pricing model with the following assumptions:

Dividend yield . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Volatility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Risk-free interest rate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Forfeiture rate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Expected life . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Stock option activity during 2001-2003 is summarized below:

2003

2002

2001

1.50%
35.10%
3.32%
0
7 years

1.54%
35.00%
3.14%
0
7 years

1.80%
33.10%
4.58%
0
7 years

Shares of
Common Stock
Attributable to Options
(in thousands)

Weighted-Average
Exercise
Price of Options

Unexercised at January 1, 2001 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Exercised . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Forfeited . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Unexercised at December 31, 2001 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Exercised . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Forfeited . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Unexercised at December 31, 2002 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Exercised . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Forfeited . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Unexercised at December 31, 2003 . . . . . . . . . . . . . . . . . . . . . . . . . . . .

45,125
26,883
(4,298)
(612)
67,098
14,133
(3,357)
(1,819)
76,055
14,361
(4,379)
(3,227)
82,810

$48.28
76.10
26.72
71.20
60.60
74.33
21.18
70.95
64.65
57.36
22.65
70.03
65.39

The following table summarizes information concerning outstanding and exercisable options at December 31,

2003 (shares in millions, contractual life in years):

Range of
Exercise
Prices

$10–$25
$25–$65
$65–$75
$75–$95

Options Outstanding
Weighted-
Average
Remaining
Contractual
Life

1.52
7.23
6.25
7.91

Weighted-
Average
Exercise
Price

$21.29
56.14
71.93
77.90

Number
Outstanding

6.76
21.37
31.51
23.17

Options Exercisable

Number
Exercisable

6.76
7.97
21.34
12.59

Weighted-
Average
Exercise
Price

$21.29
53.27
71.03
79.44

Shares exercisable at December 31, 2003, 2002, and 2001, were 48.7 million, 44.6 million, and 35.2 million,

respectively.

As noted above, the number of shares ultimately issued for the performance award program is dependent
upon the earnings achieved during the vesting period. Pursuant to this plan, approximately 0.4 million shares and
0.8 million shares were issued in 2002 and 2001, respectively. No shares were issued in 2003 and none will be is-
sued in 2004.

At December 31, 2003, additional options, performance awards, or restricted stock grants may be granted
under the 2002 Lilly Stock Plan and the Lilly GlobalShares Stock Plan for not more than 74.5 million shares and
2.1 million shares, respectively.

Note 8: Other Assets and Other Liabilities

Our sundry assets include our capitalized computer software, prepaid retiree health beneﬁ t (Note 12), goodwill
and other intangibles (Note 1), estimated insurance recoveries from our product litigation and environmental
contingencies (Note 13), and a variety of other items. The increase in sundry assets is primarily attributable to an

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increase in capitalized computer software and prepaid retiree health beneﬁ ts, offset partially by lower long-term
deferred income tax assets.

Our other current liabilities include our sales discount and rebate accruals, including our Medicaid rebate ac-
crual, deferred income from our collaboration and out-licensing arrangements, other taxes, interest payable, and
a variety of other items. Major contributors to the increase in other current liabilities are interest payable, deferred
income from our collaboration and out-licensing arrangements, and the Medicaid rebate accrual.

Our other noncurrent liabilities include the accrued liabilities from our pension and retiree health plans (Note

12), deferred income taxes (Note 11), product liability litigation and environmental accruals (Note 13), deferred
income from our collaboration and out-licensing arrangements, and a variety of other items. The increase in other
noncurrent liabilities is primarily attributable to deferred income taxes, deferred income from collaboration and
out-licensing arrangements, and accrued liabilities from our pension and retiree health plans.

None of the components of sundry assets exceeds 5 percent of total assets and none of the components of

other current liabilities or other noncurrent liabilities exceeds 5 percent of total liabilities.

Note 9: Shareholders’ Equity

Changes in certain components of shareholders’ equity were as follows:

Common Stock in Treasury

Additional
Paid-in Capital

Retained
Earnings

Deferred
Costs—ESOP

Shares
(in thousands)

(581.8)
(24.8)
229.0
18.4
0.1
359.1
2,610.0

Balance at January 1, 2001 . . . . . . . . . . . . . . . . . . . . $2,610.0
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cash dividends declared per share: $1.15 . . . . . . .
Retirement of treasury shares . . . . . . . . . . . . . . . . .
Purchase for treasury . . . . . . . . . . . . . . . . . . . . . . . .
Issuance of stock under employee stock plans . . .
ESOP transactions. . . . . . . . . . . . . . . . . . . . . . . . . . .
Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Reclassiﬁ cation . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Balance at December 31, 2001 . . . . . . . . . . . . . . . . .
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cash dividends declared per share: $1.27 . . . . . . .
Retirement of treasury shares . . . . . . . . . . . . . . . . .
Purchase for treasury . . . . . . . . . . . . . . . . . . . . . . . .
Issuance of stock under employee stock plans . . .
ESOP transactions. . . . . . . . . . . . . . . . . . . . . . . . . . .
Reclassiﬁ cation . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Balance at December 31, 2002 . . . . . . . . . . . . . . . . .
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cash dividends declared per share: $1.36 . . . . . . .
Retirement of treasury shares . . . . . . . . . . . . . . . . .
Purchase for treasury . . . . . . . . . . . . . . . . . . . . . . . .
150.4
Issuance of stock under employee stock plans . . .
13.6
ESOP transactions. . . . . . . . . . . . . . . . . . . . . . . . . . .
125.1
Reclassiﬁ cation . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Balance at December 31, 2003 . . . . . . . . . . . . . . . . . $2,610.0

131.8
13.8
248.3
2,610.0

(393.9)

(289.1)

Amount

$ 109.5

$(135.0)

1,007

$6,223.2
2,780.0
(1,232.8)

(7,368)
7,176
170

(586.7)
571.0
13.6

5.9

(129.1)

985

107.4

(4,677)
4,532
168

(396.8)
389.2
9.7

5.8

(123.3)

1,008

109.5

(0.1)
(359.1)
7,411.2
2,707.9
(1,370.7)

(248.3)
8,500.1
2,560.8
(1,465.4)

(3,180)
2,976
148

(291.2)
276.8
9.1

4.7

(125.1)
$9,470.4

$ (118.6)

952

$ 104.2

As of December 31, 2003, we have purchased $2.08 billion of our announced $3.0 billion share repurchase pro-

gram. We acquired approximately 3.0 million, 4.5 million, and 7.2 million shares in 2003, 2002, and 2001, respec-
tively, under our share repurchase programs. As previously disclosed, in connection with the share repurchase
program, we entered into agreements to purchase shares of our stock. During the second quarter of 2003, we
satisﬁ ed all our remaining obligations under the agreements.

We have 5 million authorized shares of preferred stock. As of December 31, 2003 and 2002, no preferred stock

has been issued.

We have funded an employee beneﬁ t trust with 40 million shares of Lilly common stock to provide a source of

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funds to assist us in meeting our obligations under various employee beneﬁ t plans. The funding had no net impact
on shareholders’ equity as we consolidated the employee beneﬁ t trust. The cost basis of the shares held in the
trust was $2.64 billion and is shown as a reduction in shareholders’ equity, which offset the resulting increases of
$2.61 billion in additional paid-in capital and $25 million in common stock. Any dividend transactions between us
and the trust are eliminated. Stock held by the trust is not considered outstanding in the computation of earnings
per share. The assets of the trust were not used to fund any of our obligations under these employee beneﬁ t plans
in 2003, 2002, or 2001.

We have an ESOP as a funding vehicle for the existing employee savings plan. The ESOP used the proceeds of a

loan from us to purchase shares of common stock from the treasury. The ESOP issued $200 million of third-party
debt, repayment of which was guaranteed by us (see Note 6). The proceeds were used to purchase shares of our
common stock on the open market. Shares of common stock held by the ESOP will be allocated to participating
employees annually through 2017 as part of our savings plan contribution. The fair value of shares allocated each
period is recognized as compensation expense.

Under a Shareholder Rights Plan adopted in 1998, all shareholders receive, along with each common share

owned, a preferred stock purchase right entitling them to purchase from the company one one-thousandth of
a share of Series B Junior Participating Preferred Stock (the Preferred Stock) at a price of $325. The rights are
exercisable only after the Distribution Date, which is generally the 10th business day after the date of a public an-
nouncement that a person (the Acquiring Person) has acquired ownership of 15 percent or more of our common
stock. We may redeem the rights for $.005 per right up to and including the Distribution Date. The rights will expire
on July 28, 2008, unless we redeem them earlier.

The plan provides that, if an Acquiring Person acquires 15 percent or more of our outstanding common stock
and our redemption right has expired, generally each holder of a right (other than the Acquiring Person) will have
the right to purchase at the exercise price the number of shares of our common stock that have a value of two
times the exercise price.

Alternatively, if, in a transaction not approved by the board of directors, we are acquired in a business combi-
nation transaction or sell 50 percent or more of our assets or earning power after a Distribution Date, generally
each holder of a right (other than the Acquiring Person) will have the right to purchase at the exercise price the
number of shares of common stock of the acquiring company that have a value of two times the exercise price.
At any time after an Acquiring Person has acquired 15 percent or more but less than 50 percent of our out-
standing common stock, the board of directors may exchange the rights (other than those owned by the Acquiring
Person) for our common stock or Preferred Stock at an exchange ratio of one common share (or one one-thou-
sandth of a share of Preferred Stock) per right.

Note 10: Earnings per Share

The following is a reconciliation of the denominators used in computing earnings per share:

2003

2002

2001

(Shares in thousands)

Income available to common shareholders . . . . . . . . . . . . . . . . . . . . .

$2,560.8

$2,707.9

$2,780.0

Basic earnings per share
Weighted-average number of common shares

outstanding, including incremental shares . . . . . . . . . . . . . . . .

1,076,547

1,076,922

1,077,497

Basic earnings per share . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 2.38

$ 2.51

$ 2.58

Diluted earnings per share
Weighted-average number of common

shares outstanding . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Stock options and other incremental shares. . . . . . . . . . . . . . . . . .
Weighted-average number of common

1,076,547
5,683

1,076,873
8,215

1,077,390
13,403

shares outstanding—diluted. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,082,230

1,085,088

1,090,793

Diluted earnings per share . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 2.37

$ 2.50

$ 2.55

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Note 11: Income Taxes

Following is the composition of income taxes:

Current
Federal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Foreign . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
State . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Deferred
Federal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Foreign . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
State . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Utilization of capital loss carryforwards . . . . . . . . . . . . . . . . . . . . . . .
Income taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2003

2002

2001

$391.2
284.7
(6.2)
669.7

(112.9)
138.2
5.9
31.2
—
$700.9

$140.1
306.3
(13.4)
433.0

366.1
(47.3)
(2.0)
316.8
—
$749.8

$297.6
247.9
16.6
562.1

240.5
34.6
0.2
275.3
(110.5)
$726.9

Signiﬁ cant components of our deferred tax assets and liabilities as of December 31 are as follows:

Deferred tax assets
Sale of intangibles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other carryforwards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Inventory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Compensation and beneﬁ ts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Tax credit carryforwards and carrybacks . . . . . . . . . . . . . . . . . . . .
Asset purchases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Valuation allowances . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2003

2002

$ 415.0
411.7
353.5
275.9
105.9
62.2
527.5
2,151.7
(415.3)

$ 485.3
398.4
61.3
250.0
93.6
103.0
467.6
1,859.2
(382.2)

Total deferred tax assets. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

1,736.4

1,477.0

Deferred tax liabilities
Prepaid employee beneﬁ ts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Property and equipment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Unremitted earnings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total deferred tax liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

(701.5)
(564.5)
(204.6)
(153.3)
(1,623.9)

(626.6)
(480.4)
(115.6)
(84.7)
(1,307.3)

Deferred tax assets—net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

$ 112.5

$ 169.7

At December 31, 2003, we had other carryforwards for international and U.S. income tax purposes of $266.4 mil-
lion: $150.0 million will expire within ﬁ ve years and $70.6 million thereafter; $45.8 million of the carryforwards will
never expire. The primary component of the remaining portion of the deferred tax asset for other carryforwards is
related to net operating losses for state income tax purposes that are fully reserved. We also have tax credit car-
ryforwards and carrybacks of $105.9 million available to reduce future income taxes: $46.3 million will be carried
back, $0.3 million expires after ﬁ ve years, and $9.3 million of the tax credit carryforwards will never expire. The
remaining portion of the tax credit carryforwards is related to state tax credits that are fully reserved.

Domestic and Puerto Rican companies contributed approximately 22 percent, 28 percent, and 55 percent in
2003, 2002, and 2001, respectively, to consolidated income before income taxes. At December 31, 2003, we had
an aggregate of $9.5 billion of unremitted earnings of foreign subsidiaries that have been or are intended to be
permanently reinvested for continued use in foreign operations and that, if distributed, would result in taxes at ap-
proximately the U.S. statutory rate. We have a subsidiary operating in Puerto Rico under a tax incentive grant that
begins to expire at the end of 2007.

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Cash payments of income taxes totaled $614.0 million, $864.0 million, and $320.0 million in 2003, 2002, and
2001, respectively. The increase in cash payments of income taxes in 2002 is primarily attributable to the resolu-
tion of an IRS examination.

Following is a reconciliation of the effective income tax rate applicable to income before income taxes:

United States federal statutory tax rate . . . . . . . . . . . . . . . . . . . . . . . .
Add (deduct)

International operations, including Puerto Rico . . . . . . . . . . . . . . .
General business credits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Sundry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Effective income tax rate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Note 12: Retirement Beneﬁ ts

2003

35.0%

(15.7)
(0.7)
2.9
21.5%

2002

35.0%

(12.6)
(0.7)
—
21.7%

2001

35.0%

(13.9)
(1.1)
0.7
20.7%

We used a measurement date of December 31 to develop the change in beneﬁ t obligation, change in plan assets,
funded status, and amounts recognized in the consolidated balance sheets at December 31 for our deﬁ ned beneﬁ t
pension and retiree health beneﬁ t plans, which were as follows:

Deﬁ ned Beneﬁ t Pension Plans

2003

2002

Retiree Health Beneﬁ ts

2003

2002

Change in beneﬁ t obligation
Beneﬁ t obligation at beginning of year . . . . . . . . . . . . . . . . $3,941.1
196.2
Service cost . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
266.1
Interest cost. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
105.7
Actuarial loss. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
(247.3)
Beneﬁ ts paid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Retiree health plan changes . . . . . . . . . . . . . . . . . . . . . . . .
—
Reduction in discount rate, foreign currency

$3,598.7
170.2
254.3
61.8
(234.9)
—

$911.6
38.2
60.4
136.8
(75.5)
—

exchange rate changes, and other adjustments. . . . . .

386.8
Beneﬁ t obligation at end of year . . . . . . . . . . . . . . . . . . . . . 4,648.6

91.0
3,941.1

87.3
1,158.8

Change in plan assets
Fair value of plan assets at beginning of year . . . . . . . . . .
Actual return on plan assets . . . . . . . . . . . . . . . . . . . . . . . .
Employer contribution . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Beneﬁ ts paid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Foreign currency exchange rate

3,161.3
579.2
149.1
(247.3)

changes and other adjustments . . . . . . . . . . . . . . . . . . .
Fair value of plan assets at end of year . . . . . . . . . . . . . . .

57.8
3,700.1

3,182.1
(224.9)
402.7
(234.9)

36.3
3,161.3

Funded status . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
(948.5)
Unrecognized net actuarial loss . . . . . . . . . . . . . . . . . . . . . 2,286.1
Unrecognized prior service cost (beneﬁ t) . . . . . . . . . . . . .
72.1
Net amount recognized . . . . . . . . . . . . . . . . . . . . . . . . . . . . $1,409.7

(779.8)
2,028.0
78.3
$1,326.5

Amounts recognized in the consolidated
balance sheet consisted of
Prepaid pension . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $1,613.3
Accrued beneﬁ t liability . . . . . . . . . . . . . . . . . . . . . . . . . . . .
(422.6)
Accumulated other comprehensive income

$1,515.4
(398.1)

before income taxes. . . . . . . . . . . . . . . . . . . . . . . . . . . . .

219.0
Net amount recognized . . . . . . . . . . . . . . . . . . . . . . . . . . . . $1,409.7

209.2
$1,326.5

415.0
75.3
139.1
(75.5)

—
553.9

(604.9)
847.4
(132.6)
$109.9

$192.3
(82.4)

—
$109.9

$928.2
34.0
64.5
104.6
(73.5)
(151.0)

4.8
911.6

373.4
(46.1)
161.1
(73.5)

0.1
415.0

(496.6)
698.9
(148.6)
$ 53.7

$ 127.3
(73.6)

—
$ 53.7

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(Percents)

Deﬁ ned Beneﬁ t Pension Plans
2002
2003

Retiree Health Beneﬁ ts

2003

2002

Weighted-average assumptions as of December 31
6.2
Discount rate for beneﬁ t obligation . . . . . . . . . . . . . . . . . .
6.8
Discount rate for net beneﬁ t costs . . . . . . . . . . . . . . . . . . .
Rate of compensation increase for beneﬁ t obligation . . . 3.0–5.5
Rate of compensation increase for net beneﬁ t costs . . . . 3.0–5.5
9.27
Expected return on plan assets for net beneﬁ t costs. . . .

6.8
7.2
3.0–5.5
3.5–8.0
10.5

6.2
6.9
—
—
9.25

6.9
7.4
—
—
10.5

In evaluating the expected return on plan assets, we have considered our historical assumptions compared

with actual results, an analysis of current market conditions, asset allocations, and the views of leading ﬁ nancial
advisers and economists. Including the investment losses due to overall market conditions in 2001 and 2002, our
10- and 20-year annualized rate of return on our U.S. deﬁ ned beneﬁ t pension plans and retiree health beneﬁ t plan
was approximately 9.2 percent and 11.5 percent, respectively, as of December 31, 2003. Health-care-cost trend
rates were assumed to increase at an annual rate of 10 percent in 2003, decreasing 1 percent per year to 6 percent
in 2007 and thereafter.

The total accumulated beneﬁ t obligation for all our deﬁ ned beneﬁ t pension plans was $3.93 billion and
$3.47 billion at December 31, 2003 and 2002, respectively. The projected beneﬁ t obligation, accumulated beneﬁ t
obligation, and fair value of the plan assets for the deﬁ ned beneﬁ t pension plans with projected beneﬁ t obligations
in excess of plan assets were $4.65 billion, $3.93 billion, and $3.70 billion, respectively, as of December 31, 2003,
and $3.94 billion, $3.47 billion, and $3.16 billion, respectively, as of December 31, 2002.
Net pension and retiree health beneﬁ t expense included the following components:

Deﬁ ned Beneﬁ t Pension Plans
2002

2003

2001

2003

Retiree Health Beneﬁ ts
2002

2001

Components of net periodic beneﬁ t cost
Service cost . . . . . . . . . . . . . . . . . . . . . . .
Interest cost. . . . . . . . . . . . . . . . . . . . . . .
Expected return on plan assets . . . . . .
Amortization of prior service cost . . . .
Recognized actuarial loss . . . . . . . . . . .
Net periodic beneﬁ t cost . . . . . . . . . . . .

$196.2
266.1
(382.0)
11.9
52.0
$144.2

$170.2
254.3
(398.0)
16.1
21.9
$ 64.5

$156.0
242.4
(382.3)
19.3
9.8
$ 45.2

$38.2
60.4
(53.6)
(15.6)
50.6
$80.0

$34.0
64.5
(50.8)
(0.7)
36.0
$83.0

$28.7
53.8
(40.1)
0.1
23.6
$66.1

If the health-care-cost trend rates were to be increased by one percentage point each future year, the Decem-

ber 31, 2003, accumulated postretirement beneﬁ t obligation would increase by 11.3 percent and the aggregate of
the service cost and interest cost components of the 2003 annual expense would increase by 15.3 percent. A one-
percentage-point decrease in these rates would decrease the December 31, 2003, accumulated postretirement
beneﬁ t obligation by 10.1 percent and the aggregate of the 2003 service cost and interest cost by 13.2 percent.

We have deﬁ ned contribution savings plans that cover our eligible employees worldwide. The purpose of these

deﬁ ned contribution plans is generally to provide additional ﬁ nancial security during retirement by providing em-
ployees with an incentive to save. Our contributions to the plan are based on employee contributions and the level
of our match. Expenses under the plans totaled $72.9 million, $41.7 million, and $39.3 million for the years 2003,
2002, and 2001, respectively.

We provide certain other postemployment beneﬁ ts primarily related to disability beneﬁ ts and accrue for the
related cost over the service lives of employees. Expenses associated with these beneﬁ t plans in 2003, 2002, and
2001 were not signiﬁ cant.

Our plan assets in our U.S. deﬁ ned beneﬁ t pension and retiree health plans comprise approximately 86 per-
cent of our worldwide beneﬁ t plan assets. Our U.S. deﬁ ned beneﬁ t pension and retiree health beneﬁ t plan invest-
ment allocation strategy currently comprises approximately 85 percent to 95 percent growth investments and
5 percent to 15 percent ﬁ xed-income investments. Within the growth investment classiﬁ cation, the plan asset
strategy encompasses equity and equity-like instruments that are expected to represent approximately 75 percent
of our plan asset portfolio of both public and private market investments. The largest component of these equity
and equity-like instruments is public equity securities that are well diversiﬁ ed and invested in U.S. and interna-
tional small-to-large companies. The remaining portion of the growth investment classiﬁ cation is represented by
other alternative growth investments.

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Our U.S. deﬁ ned beneﬁ t pension plan and retiree health plan asset allocations as of December 31 are as follows:

(Percents)

Percentage of
Pension Plan Assets

Percentage of
Retiree Health Plan Assets

2003

2002

2003

2002

Asset Category
Equity securities and equity-like instruments . . . . . . . . . . . .
Debt securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Real estate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

77%
10
2
11
100%

86%
10
3
1
100%

81%
12
1
6
100%

85%
12
1
2
100%

In 2004, we expect to contribute approximately $26.0 million to our deﬁ ned beneﬁ t pension plans to satisfy
minimum funding requirements in 2004. In addition, we expect to contribute approximately an additional $300.0
million of discretionary funding in 2004 to our deﬁ ned beneﬁ t plans. We also expect to contribute approximately
$125.0 million of discretionary funding to our postretirement health beneﬁ t plans during 2004.

Note 13: Contingencies

Three generic pharmaceutical manufacturers, Zenith Goldline Pharmaceuticals, Inc. (Zenith), Dr. Reddy’s Labora-
tories, Ltd. (Reddy), and Teva Pharmaceuticals, have submitted abbreviated new drug applications (ANDAs) seek-
ing permission to market generic versions of Zyprexa in various dosage forms several years prior to the expiration
of our U.S. patents for the product, alleging that our patents are invalid or not infringed. We ﬁ led suits against the
three companies in U.S. District Court for the Southern District of Indiana seeking a ruling that the challenges to
our compound patent (expiring in 2011) are without merit. The cases have been consolidated. A trial before a dis-
trict court judge in Indianapolis began on January 26, 2004, and is expected to conclude in February. A ruling from
the trial court is expected in the second or third quarter of 2004. Regardless of the trial court ruling, we anticipate
that appeals will follow. If we are unsuccessful at the trial court level, we cannot predict whether any of the generic
companies would launch generic versions of Zyprexa prior to a ﬁ nal resolution of any appeals. We believe that the
generic manufacturers’ claims are without merit and we expect to prevail in this litigation. However, it is not pos-
sible to predict or determine the outcome of this litigation and, accordingly, we can provide no assurance that we
will prevail. An unfavorable outcome would have a material adverse impact on our consolidated results of opera-
tions, liquidity, and ﬁ nancial position.

In October 2002, we were notiﬁ ed that Barr Laboratories, Inc. (Barr), had submitted an ANDA to the U.S. FDA
seeking permission to market a generic version of Evista several years prior to the expiration of our U.S. patents
covering the product, alleging that the patents are invalid or not infringed. On November 26, 2002, we ﬁ led suit
against Barr in federal district court in Indianapolis seeking a ruling that Barr’s challenges to our patents claiming
the method of use and pharmaceutical form (expiring from 2012 to 2017) are without merit. In June 2003, Barr add-
ed a challenge to one of our additional patents (expiring in 2017) claiming a component in the pharmaceutical form
of Evista. This patent has now been added to the lawsuit. The trial is tentatively scheduled to begin in August 2005.
While we believe that Barr’s claims are without merit and expect to prevail, it is not possible to predict or determine
the outcome of the litigation. Therefore, we can provide no assurance that we will prevail. An unfavorable outcome
could have a material adverse impact on our consolidated results of operations, liquidity, and ﬁ nancial position.

In July 2002, we received a grand jury subpoena for documents from the Ofﬁ ce of Consumer Litigation, Depart-
ment of Justice, related to our marketing and promotional practices and physician communications with respect to
Evista. We received a second subpoena seeking additional documents in July 2003. We continue to cooperate with
the government and have provided a broad range of information concerning our U.S. marketing and promotional
practices, including documents relating to communications with physicians and the remuneration of physician
consultants and advisers. We continue to review and enhance policies and procedures designed to assure that our
marketing and promotional practices and physician communications comply with promotional laws and regula-
tions. In recent months, several pharmaceutical companies have received subpoenas from government agencies
with respect to a variety of products, including a number of neuroscience products. It is possible that other Lilly
products, including Zyprexa, could become subject to investigation. It is possible that the outcome of the above mat-
ters could include criminal charges and ﬁ nes and/or civil penalties. We cannot predict or determine the outcome
of the above matters or reasonably estimate the amount or range of amounts of any ﬁ nes or penalties that might
result from an adverse outcome. It is possible, however, that an adverse outcome could have a material adverse
impact on our consolidated ﬁ nancial position, liquidity, and results of operations.

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We have been named as a defendant in numerous product liability lawsuits involving primarily two products,
diethylstilbestrol (DES) and thimerosal. We have accrued for the estimated exposure with respect to all current
product liability claims. In addition, we have accrued for certain claims incurred, but not ﬁ led, to the extent we can
formulate a reasonable estimate of their costs. We estimate these expenses based primarily on historical claims
experience and data regarding product usage. We expect the cash amounts related to the accruals to be paid out
over the next several years. A portion of the costs associated with defending and disposing of these suits is covered
by insurance. We estimate insurance recoverables based on existing deductibles, coverage limits, and the existing
and projected future level of insolvencies among the insurance carriers.

Under the Comprehensive Environmental Response, Compensation, and Liability Act, commonly known as

Superfund, we have been designated as one of several potentially responsible parties with respect to fewer than
10 sites. Under Superfund, each responsible party may be jointly and severally liable for the entire amount of
the cleanup. We also continue remediation of certain of our own sites. We have accrued for estimated Superfund
cleanup costs, remediation, and certain other environmental matters, taking into account, as applicable, available
information regarding site conditions, potential cleanup methods, estimated costs, and the extent to which other
parties can be expected to contribute to payment of those costs. We have reached a settlement with our liability
insurance carriers providing for coverage for certain environmental liabilities.

The environmental liabilities and litigation accruals have been reﬂ ected in our consolidated balance sheet at
the gross amount of approximately $258.7 million at December 31, 2003. Estimated insurance recoverables of ap-
proximately $83.2 million at December 31, 2003, have been reﬂ ected as assets in the consolidated balance sheet.

While it is not possible to predict or determine the outcome of the patent, product liability, or other legal ac-

tions brought against us or the ultimate cost of environmental matters, we believe that, except as noted above
in this note in connection with the discussion of the Zyprexa patent litigation, the Evista patent litigation, and our
marketing and promotional practices, the resolution of all such matters will not have a material adverse effect on
our consolidated ﬁ nancial position or liquidity but could possibly be material to the consolidated results of opera-
tions in any one accounting period.

Note 14: Other Comprehensive Income (Loss)

The accumulated balances related to each component of other comprehensive income (loss) were as follows:

Beginning balance at January 1, 2003. . . . . . . . . . .
Other comprehensive income (loss) . . . . . . . . . . . .
Balance at December 31, 2003. . . . . . . . . . . . . . . . .

Foreign
Currency
Translation

$(356.5)
473.2
$ 116.7

Unrealized
Gains
(Losses) on
Securities

$ (2.9)
45.4
$42.5

Minimum
Pension
Liability
Adjustment

$ (137.8)
(6.4)
$(144.2)

Effective
Portion of
Cash Flow
Hedges

Accumulated
Other
Comprehensive
Income (Loss)

$(173.6)
(1.5)
$(175.1)

$(670.8)
510.7
$(160.1)

The amounts above are net of income taxes. The income taxes related to other comprehensive income were

not signiﬁ cant as income taxes were generally not provided for foreign currency translation.

The unrealized gains (losses) on securities is net of reclassiﬁ cation adjustments of $37.4 million, $11.3 million,

and $12.3 million, net of tax, in 2003, 2002, and 2001, respectively, for net realized gains on sales of securities in-
cluded in net income. The effective portion of cash ﬂ ow hedges is net of reclassiﬁ cation adjustments of $27.2 million
in 2003, net of tax, for realized losses on foreign currency options and $14.2 million and $6.5 million, net of tax, in
2003 and 2002, respectively, for interest expense on interest rate swaps designated as cash ﬂ ow hedges. In 2001,
reclassiﬁ cation adjustments were $16.5 million, net of tax, for realized gains on foreign currency options.

Generally, the assets and liabilities of foreign operations are translated into U.S. dollars using the current
exchange rate. For those operations, changes in exchange rates generally do not affect cash ﬂ ows; therefore,
resulting translation adjustments are made in shareholders’ equity rather than in income.

RESPONSIBILITY FOR FINANCIAL STATEMENTS

Eli Lilly and Company and Subsidiaries

Management of Eli Lilly and Company is responsible for the fair presentation of the ﬁ nancial statements and has
full responsibility for their accuracy and integrity. The statements have been prepared in accordance with gener-
ally accepted accounting principles in the United States and include amounts based on judgments and estimates by
management.

We have global ﬁ nancial policies that govern critical areas, including internal controls, ﬁ nancial accounting
and reporting, ﬁ duciary accountability, and safeguarding of corporate assets. Our internal accounting control sys-
tems are designed to provide reasonable assurance that assets are safeguarded, that transactions are executed in
accordance with management’s authorization and are properly recorded, and that accounting records are adequate
for preparation of ﬁ nancial statements and other ﬁ nancial information. The design, monitoring, and revision of
internal accounting control systems involve, among other things, management’s judgments with respect to the
relative cost and expected beneﬁ ts of speciﬁ c control measures. A staff of internal auditors regularly monitors,
on a worldwide basis, the adequacy and effectiveness of internal accounting controls. The general auditor reports
directly to the audit committee of the board of directors.

In addition to the system of internal accounting controls, we maintain a code of conduct (known as The Red

Book) that applies to all employees worldwide, requiring proper overall business conduct, avoidance of conﬂ icts
of interest, compliance with laws, and conﬁ dentiality of proprietary information. The Red Book is reviewed on a
periodic basis with employees worldwide and all employees are required to report suspected violations. A hotline
number is published in The Red Book to enable employees to report suspected violations anonymously. Employees
who report suspected violations are protected from discrimination or retaliation by the company. In addition to The
Red Book, the CEO and all ﬁ nancial management must agree, in writing, to a ﬁ nancial code of ethics, which further
reinforces their ﬁ duciary responsibilities.

The ﬁ nancial statements have been audited by Ernst & Young LLP, independent auditors. Their responsibility is

to examine our consolidated ﬁ nancial statements in accordance with generally accepted auditing standards in the
United States and to express their opinion with respect to the fairness of presentation of the statements. Ernst &
Young reports directly to the audit committee of the board of directors.

Our audit committee comprises four nonemployee members of the board of directors, all of whom are inde-

pendent from our company. The committee charter, which is published in the proxy statement, outlines the mem-
bers’ roles and responsibilities and is consistent with the recently enacted corporate reform laws and regulations.
It is the audit committee’s responsibility to appoint independent auditors subject to shareholder ratiﬁ cation, ap-
prove both audit and nonaudit services performed by the independent auditors, and review the reports submitted
by them. The audit committee meets several times during the year with management, the internal auditors, and
the independent auditors to discuss audit activities, internal controls, and ﬁ nancial reporting matters, including
reviews of our externally published ﬁ nancial results. The internal auditors and the independent auditors have full
and free access to the committee.

We are dedicated to ensuring that we maintain the high standards of ﬁ nancial accounting and reporting that
we have established. We are committed to providing ﬁ nancial information that is transparent, timely, complete, rel-
evant, and accurate. Our culture demands integrity and an unyielding commitment to strong internal practices and
policies. Finally, we have the highest conﬁ dence in our ﬁ nancial reporting, underlying system of internal controls,
and our people, who are objective in their responsibilities and operate under a code of conduct and the highest
level of ethical standards.

Sidney Taurel
Chairman of the Board, President, and Chief Executive Ofﬁ cer

Charles E. Golden
Executive Vice President and Chief Financial Ofﬁ cer
February 2, 2004

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REPORT OF INDEPENDENT AUDITORS

Board of Directors and Shareholders
Eli Lilly and Company

We have audited the accompanying consolidated balance sheets of Eli Lilly and Company and subsidiaries as of
December 31, 2003 and 2002, and the related consolidated statements of income, cash ﬂ ows, and comprehensive
income for each of the three years in the period ended December 31, 2003. These ﬁ nancial statements are the
responsibility of the company’s management. Our responsibility is to express an opinion on these ﬁ nancial state-
ments based on our audits.

We conducted our audits in accordance with auditing standards generally accepted in the United States. Those
standards require that we plan and perform the audit to obtain reasonable assurance about whether the ﬁ nancial
statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the ﬁ nancial statements. An audit also includes assessing the accounting prin-
ciples used and signiﬁ cant estimates made by management, as well as evaluating the overall ﬁ nancial statement
presentation. We believe that our audits provide a reasonable basis for our opinion.

In our opinion, the ﬁ nancial statements referred to above present fairly, in all material respects, the consoli-
dated ﬁ nancial position of Eli Lilly and Company and subsidiaries at December 31, 2003 and 2002, and the consoli-
dated results of their operations and their cash ﬂ ows for each of the three years in the period ended December 31,
2003, in conformity with accounting principles generally accepted in the United States.

Indianapolis, Indiana
February 2, 2004

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NOTICE OF 2004 ANNUAL MEETING AND PROXY STATEMENT

March 12, 2004

Dear Shareholder:

You are cordially invited to attend our annual meeting of shareholders on Monday, April 19, 2004, at the Lilly Center
Auditorium, Lilly Corporate Center, Indianapolis, Indiana, at 11:00 a.m. EST (Indianapolis time). If you are unable to
attend in person, please join us via live webcast on the company’s website at www.lilly.com.

The notice of meeting and proxy statement that follow describe the business we will consider at the meeting. Your
vote is very important. I urge you to vote by mail, by telephone, or on the Internet in order to be certain your shares
are represented at the meeting even if you plan to attend.

Please note our procedures for admission to the meeting described on page 49.

I look forward to seeing you at the meeting.

Sidney Taurel
Chairman of the Board, President, and Chief Executive Ofﬁ cer

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Notice of Annual Meeting of Shareholders
April 19, 2004

The annual meeting of shareholders of Eli Lilly and Company will be held at the Lilly Center Auditorium, Lilly
Corporate Center, Indianapolis, Indiana, on Monday, April 19, 2004, at 11:00 a.m. EST (Indianapolis time) for the fol-
lowing purposes:

• to elect four directors of the company to serve three-year terms
• to ratify the appointment by the audit committee of Ernst & Young LLP as principal independent auditors for the

year 2004

• to approve the Eli Lilly and Company Bonus Plan
• to consider and vote on a shareholder proposal requesting that the company’s board of directors adopt a com-

pensation program limiting the compensation of senior executives to speciﬁ ed levels

• to consider and vote on a shareholder proposal requesting that the company’s board of directors report on how

the company will respond to pressure to increase access to and affordability of prescription drugs.

Shareholders of record at the close of business on February 13, 2004, will be entitled to vote at the meeting and
any adjournment of the meeting.

Attendance at the meeting will be limited to shareholders, those holding proxies from shareholders, and invited
guests from the media and ﬁ nancial community. A page at the back of this proxy statement contains an admission
ticket. If you plan to attend the meeting, please bring this ticket with you.

This combined proxy statement and annual report to shareholders and the proxy are being mailed on or about
March 12, 2004.

By order of the board of directors,

Alecia A. DeCoudreaux
Secretary

March 12, 2004
Indianapolis, Indiana

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GENERAL INFORMATION

Why did I receive this proxy statement?

The board of directors of Eli Lilly and Company is soliciting proxies to be voted at the annual meeting of sharehold-
ers (the annual meeting) to be held on Monday, April 19, 2004, and at any adjournment of the annual meeting. When
the company asks for your proxy, we must provide you with a proxy statement that contains certain information
speciﬁ ed by law.

What will the shareholders vote on at the annual meeting?

Five items:
• election of directors
• ratiﬁ cation of the appointment of principal independent auditors
• approval of the Eli Lilly and Company Bonus Plan
• a shareholder proposal requesting that we adopt a compensation program limiting the compensation of senior

executives

• a shareholder proposal requesting that the company’s board of directors report on how the company will re-

spond to pressure to increase access to and affordability of prescription drugs.

Will there be any other items of business on the agenda?

We do not expect any other items of business because the deadline for shareholder proposals and nominations
has already passed. Nonetheless, in case there is an unforeseen need, the accompanying proxy gives discretion-
ary authority to the persons named on the proxy with respect to any other matters that might be brought before the
meeting. Those persons intend to vote that proxy in accordance with their best judgment.

Who is entitled to vote?

Shareholders as of the close of business on February 13, 2004 (the record date), may vote at the annual meeting.
You have one vote for each share of common stock you held on the record date, including shares:
• held directly in your name as the shareholder of record
• held for you in an account with a broker, bank, or other nominee
• attributed to your account in the Lilly Employee Savings Plan (the savings plan).

What constitutes a quorum?

A majority of the outstanding shares, present or represented by proxy, constitutes a quorum for the annual meet-
ing. As of the record date, 1,124,294,251 shares of company common stock were issued and outstanding.

How many votes are required for the approval of each item?

There are differing vote requirements for the various proposals.
• The four nominees for director receiving the most votes will be elected. Abstentions and instructions to withhold
authority to vote for one or more of the nominees will result in those nominees receiving fewer votes but will not
count as votes against a nominee.

• The appointment of principal independent auditors and the Eli Lilly and Company Bonus Plan will be approved if
the votes cast for the proposal exceed those cast against the proposal. Abstentions will not be counted either for
or against the proposal.

• The shareholder proposals will be approved if the votes cast for the proposal exceed those cast against the pro-

posal. Abstentions and broker nonvotes will not be counted either for or against the proposal.

Broker nonvotes. If your shares are held by a broker, the broker will ask you how you want your shares to be voted.
If you give the broker instructions, your shares will be voted as you direct. If you do not give instructions, one of
two things can happen, depending on the type of proposal. For the election of directors, ratiﬁ cation of auditors, and
approval of the Eli Lilly and Company Bonus Plan, the broker may vote your shares in its discretion. For the share-

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holder proposals, the broker may not vote your shares at all. When that happens, it is called a “broker nonvote.”

How do I vote by proxy?

If you are a shareholder of record, you may vote your proxy by any one of the following methods.

By mail. Sign and date each proxy card you receive and return it in the prepaid envelope. Sign your name exactly as
it appears on the proxy. If you are signing in a representative capacity (for example, as an attorney-in-fact, executor,
administrator, guardian, trustee, or the ofﬁ cer or agent of a corporation or partnership), please indicate your name
and your title or capacity. If the stock is held in custody for a minor (for example, under the Uniform Transfers to
Minors Act), the custodian should sign, not the minor. If the stock is held in joint ownership, one owner may sign on
behalf of all owners. If you return your signed proxy but do not indicate your voting preferences, we will vote on your
behalf for the election of the four nominees for director listed below, for the ratiﬁ cation of the appointment of the
independent auditors, for the Eli Lilly and Company Bonus Plan, and against the shareholder proposals.

Note that if you previously elected to receive these materials electronically, you did not receive a proxy card. If you
wish to vote by mail, rather than by telephone or on the Internet as discussed below, you may request paper copies
of these materials, including a proxy card, by calling 317-433-5112 or by sending an e-mail message to annual_
meeting@lilly.com. Please make sure you give us the control number from the e-mail message that you received
notifying you of the electronic availability of these materials and your name and mailing address.

By telephone. Shareholders in the United States, Puerto Rico, and Canada may vote by telephone by following the
instructions on the enclosed proxy card or, if you received these materials electronically, by following the instruc-
tions in the e-mail message that notiﬁ ed you of their availability. Voting by telephone has the same effect as voting
by mail. If you vote by telephone, do not return your proxy card. If you want to vote by telephone, you must do so
before 11:59 p.m. EDT (10:59 p.m. Indianapolis time), April 18, 2004.

By Internet. You may vote online at www.proxyvote.com. Follow the instructions on the enclosed proxy card or, if you
received these materials electronically, the instructions in the e-mail message that notiﬁ ed you of their availability.
Voting on the Internet has the same effect as voting by mail. If you vote on the Internet, do not return your proxy card.
If you want to vote on the Internet, you must do so before 11:59 p.m. EDT (10:59 p.m. Indianapolis time), April 18, 2004.

You have the right to revoke your proxy at any time before the meeting by (1) notifying the company’s secretary in
writing or (2) delivering a later-dated proxy by telephone, on the Internet, or in writing. If you are a shareholder of
record, you may also revoke your proxy by voting in person at the meeting.

How do I vote my shares that are held by my broker?

If you have shares held by a broker or other nominee, you may instruct your broker or other nominee to vote your
shares by following instructions that the broker or nominee provides for you. Most brokers offer voting by mail,
telephone, and on the Internet.

How do I vote in person?

If you are a shareholder of record, you may vote your shares in person at the meeting. However, we encourage you
to vote by proxy card, by telephone, or on the Internet even if you plan to attend the meeting.

How do I vote my shares in the Savings Plan?

You may instruct the plan trustee on how to vote your shares in the savings plan by mail, by telephone, or on the
Internet as described above, except that, if you vote by mail, the card that you use will be a voting instruction card
rather than a proxy card.

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How many shares in the Savings Plan can I vote?

You may vote all the shares allocated to your account on the record date. In addition, unless you decline, your vote
will also apply to a proportionate number of other shares held in the plan for which voting directions are not re-
ceived. These undirected shares include:
• shares credited to the accounts of participants who do not return their voting instructions (except for a small

number of shares from a prior stock ownership plan, which can be voted only on the directions of the participants
to whose accounts the shares are credited)

• shares held in the plan that are not yet credited to individual participants’ accounts.

All participants are named ﬁ duciaries under the terms of the savings plan and under the Employee Retirement
Income Security Act (ERISA) for the limited purpose of voting shares credited to their accounts and the portion of
undirected shares to which their vote applies. Under ERISA, ﬁ duciaries are required to act prudently in making vot-
ing decisions.

If you do not want to have your vote applied to the undirected shares, you should check the box marked “I decline.”
Otherwise, the trustee will automatically apply your voting preferences to the undirected shares proportionally
with all other participants who elected to have their votes applied in this manner.

What happens if I do not vote my Savings Plan shares?

Your shares will be voted by other plan participants who have elected to have their voting preferences applied pro-
portionally to all shares for which voting instructions are not otherwise received.

What does it mean if I receive more than one proxy card?

It means that you hold shares in more than one account. To ensure that all your shares are voted, sign and return
each card. Alternatively, if you vote by telephone or on the Internet, you will need to vote once for each proxy card
and voting instruction card you receive.

What should I do if I want to attend the annual meeting?

All shareholders as of the record date may attend by presenting the admission ticket that appears at the end of this
proxy statement. Please ﬁ ll it out and bring it with you to the meeting. The meeting will be held at the Lilly Center Audi-
torium. Please use the Lilly Center entrance to the south of the fountain at the corner of Delaware and McCarty Streets.
You will need to pass through security, including a metal detector. Present your ticket to the usher at the meeting.

Parking will be available on a ﬁ rst-come, ﬁ rst-served basis at the garage indicated in the map on page 95.

If you have questions about admittance or parking, you may call 317-433-5112 or send an e-mail message to
annual_meeting@lilly.com.

Will the annual meeting be available on the Internet?

The annual meeting will be webcast live on the company’s website. To join the live webcast, go to www.lilly.com and
click on the annual meeting link that appears on the home page. The webcast will be available in both the Windows
Media™ Player and RealPlayer® formats. The annual meeting will be available for replay on the Lilly website until
May 19, 2004.

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How do I contact the board of directors?

The board has a process by which shareholders can send communications to the board. You can send written com-
munications to one or more members of the board, addressed to

Presiding Director, Board of Directors
Eli Lilly and Company
c/o Corporate Secretary
Lilly Corporate Center
Indianapolis, Indiana 46285.

All such communications will be forwarded to the relevant director(s) except for solicitations or other matters
unrelated to the company.

How do I submit a shareholder proposal for the 2005 annual meeting?

The company’s 2005 annual meeting is scheduled for April 18, 2005. If a shareholder wishes to have a proposal
considered for inclusion in next year’s proxy statement, he or she must submit the proposal in writing so that we
receive it by November 12, 2004. Proposals should be addressed to the company’s secretary, Lilly Corporate Cen-
ter, Indianapolis, Indiana 46285. In addition, the company’s bylaws provide that any shareholder wishing to propose
any other business at the annual meeting must also give the company written notice by November 12, 2004. That
notice must provide certain other information as described in the bylaws. Copies of the bylaws are available online
at http://investor.lilly.com/bylaws.cfm.

Does the company offer an opportunity to receive future proxy materials electronically?

Yes. If you are a shareholder of record or a member of the savings plan, you may, if you wish, receive future proxy state-
ments and annual reports online. If you elect this feature, you will receive an e-mail message notifying you when the
materials are available along with a web address for viewing the materials and instructions for voting by telephone or
the Internet. If you have more than one account, you may receive separate e-mail notiﬁ cations for each account.

You may sign up for electronic delivery in two ways.

• If you vote online as described above, you may sign up for electronic delivery at that time.
• You may sign up at any time by visiting http://proxyonline.lilly.com.

If you received these materials electronically, you do not need to do anything to continue receiving materials elec-
tronically in the future.

If you hold your shares in a brokerage account, you may also have the opportunity to receive proxy materials elec-
tronically. Please follow the instructions of your broker.

What are the beneﬁ ts of electronic delivery?

Electronic delivery reduces the company’s printing and mailing costs. It is also a convenient way for you to receive
your proxy materials and makes it easy to vote your shares online. If you have shares in more than one account, it
is an easy way to avoid receiving duplicate copies of proxy materials.

What are the costs of electronic delivery?

The company charges nothing for electronic delivery. You may, of course, incur the usual expenses associated with
Internet access, such as telephone charges or charges from your Internet service provider.

May I change my mind later?

Yes. You may discontinue electronic delivery at any time. For more information, call 317-433-5112 or send an
e-mail message to annual_meeting@lilly.com.

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What is “householding”?

We have adopted “householding,” a procedure under which shareholders of record who have the same address
and last name and do not receive proxy materials electronically will receive only one copy of our annual report and
proxy statement unless one or more of these shareholders notiﬁ es us that they wish to continue receiving individu-
al copies. This procedure saves printing and postage costs by reducing duplicative mailings.

Shareholders who participate in householding will continue to receive separate proxy cards. Householding will not
affect dividend check mailings.

Beneﬁ cial shareholders can request information about householding from their banks, brokers, or other holders of
record.

What if I want to receive a separate copy of the proxy statement?

If you participate in householding and wish to receive a separate copy of the combined 2003 annual report and
proxy statement, or if you wish to receive separate copies of future annual reports and proxy statements, please
call us at 317-433-5112 or write to: Householding Department, 51 Mercedes Way, Edgewood, NY 11717. We will
deliver the requested documents to you promptly upon your request.

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BOARD OF DIRECTORS

Directors’ Biographies

Class of 2004
The following four directors’ terms will expire at this year’s annual meeting. Each of these directors has been nom-
inated and is standing for election to serve another term that will expire in 2007. Dr. Beering, who will retire from
the board following the 2005 annual meeting in accordance with our retirement policy for independent directors,
will only serve one year of this term. See page 75 of this proxy statement for more information.

Steven C. Beering, M.D.
President Emeritus, Purdue University
Director since 1983
Age 71

Dr. Beering served as president of Purdue University from 1983 until his retirement
in 2000 when he became president emeritus of the university. He served as dean
of the Indiana University School of Medicine and director of the Indiana University
Medical Center from 1974 until 1983. Dr. Beering is a fellow of the American College
of Physicians and the Royal Society of Medicine and a member of the National
Academy of Sciences Institute of Medicine and the National Science Board. He is a
director of American United Life Insurance Company and NiSource, Inc.; director
and past chairman of the Purdue Research Foundation; and a trustee of Universities
Research Association, Inc. Dr. Beering is the past national chairman of the
Association of American Universities and a trustee of the University of Pittsburgh.

Sir Winfried Bischoff
Chairman, Citigroup Europe
Director since 2000
Age 62

Sir Winfried Bischoff has served as chairman, Citigroup Europe, since April 2000.
From 1995 to 2000, he was chairman of Schroders, plc. He joined the Schroder
Group in 1966 where he held a number of positions, including chairman of J.
Henry Schroder Co. and group chief executive of Schroders, plc. He is a nonex-
ecutive director of The McGraw-Hill Companies, Inc.; Land Securities plc; and
IFIL-Finanziaria di Partecipazioni SPA, Italy.

Franklyn G. Prendergast, M.D., Ph.D.
Edmond and Marion Guggenheim Professor of Biochemistry and Molecular
Biology and Professor of Molecular Pharmacology and Experimental Thera-
peutics, Mayo Medical School
Director, Mayo Clinic Cancer Center
Director since 1995
Age 58

Dr. Prendergast is the Edmond and Marion Guggenheim Professor of Biochemis-
try and Molecular Biology and Professor of Molecular Pharmacology and Experi-
mental Therapeutics at Mayo Medical School and the director of the Mayo Clinic
Cancer Center. He has held several other teaching positions at the Mayo Medical
School since 1975. Dr. Prendergast serves on the board of trustees of the Mayo
Foundation and its executive committee.

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Kathi P. Seifert
Executive Vice President, Kimberly-Clark Corporation
Director since 1995
Age 54

Ms. Seifert is executive vice president for Kimberly-Clark Corporation. She
joined Kimberly-Clark in 1978 and has served in several capacities in connection
with both the domestic and international consumer products businesses. Prior
to joining Kimberly-Clark, Ms. Seifert held management positions at Procter &
Gamble, Beatrice Foods, and Fort Howard Paper Company. She is a director of
Theda Care Health Group, the U.S. Fund for UNICEF, and the Fox Cities Perform-
ing Arts Center. Ms. Seifert has announced her retirement from Kimberly-Clark,
effective June, 2004.

Class of 2005
The following four directors will continue in ofﬁ ce until 2005.

George M.C. Fisher
Retired Chairman of the Board and Chief Executive Ofﬁ cer, Eastman Kodak
Company
Director since 2000
Age 63

Mr. Fisher served as chairman of the board of Eastman Kodak Company from 1993
to December 2000. He also served as chairman and chief executive ofﬁ cer from
1993 until 1999 and as president from 1993 until 1996. Prior to joining Kodak, he
was an executive ofﬁ cer of Motorola, Inc., serving as chairman and chief executive
ofﬁ cer from 1990 to October 1993, and president and chief executive ofﬁ cer from
1988 to 1990. Mr. Fisher is a director of Delta Air Lines, Inc., and General Motors
Corporation. He is chairman of the National Academy of Engineering and a mem-
ber of The Business Council.

Alfred G. Gilman, M.D., Ph.D.
Regental Professor and Chairman, Department of Pharmacology, The Univer-
sity of Texas Southwestern Medical Center
Director since 1995
Age 62

Dr. Gilman has served as professor and chairman of the Department of Pharma-
cology at The University of Texas Southwestern Medical Center since 1981. He has
held the Raymond and Ellen Willie Distinguished Chair in Molecular Neurophar-
macology at the University since 1987 and was named a regental professor in 1995.
Dr. Gilman was on the faculty of the University of Virginia School of Medicine from
1971 until 1981 where he was named a professor of pharmacology in 1977. He is
a director of Regeneron Pharmaceuticals, Inc. Dr. Gilman was a recipient of the
Nobel Prize in Physiology or Medicine in 1994.

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Karen N. Horn, Ph.D.
Retired President, Private Client Services, and Managing Director, Marsh, Inc.
Director since 1987
Age 60

Ms. Horn served as president, Private Client Services, and managing director of
Marsh, Inc., a subsidiary of MMC from 1999 until her retirement in 2003. Prior
to joining Marsh, she was senior managing director and head of international
private banking at Bankers Trust Company; chairman and chief executive ofﬁ cer,
Bank One, Cleveland, N.A.; president of the Federal Reserve Bank of Cleveland;
treasurer of Bell of Pennsylvania; and vice president of First National Bank of
Boston. Ms. Horn serves as director of T. Rowe Price Mutual Funds and The U.S.
Russia Investment Fund, a presidential appointment.

Sir John Rose
Chief Executive Rolls-Royce Group plc
Director since 2003
Age 51

Sir John Rose is chief executive of Rolls-Royce plc. Sir John joined Rolls-Royce
in 1984, became a member of its board in 1992, and was named chief executive
in 1996. Sir John is a fellow of the Royal Aeronautical Society, a past president of
AECMA (The European Association of Aerospace Industries), a past president of
the Society of British Aerospace Companies, and a member of the Council of The
Prince’s Trust as chairman of The Prince’s Trust-Business. He is a member of the
J.P. Morgan International Council, the CBI International Advisory Board, the Advi-
sory Board of the Economic Development Board of Singapore, and The Engleﬁ eld
Advisory Board. Sir John is also a member of the European Round Table of Indus-
trialists. He has been serving under interim election since December 2003.

Class of 2006
The following four directors will continue in ofﬁ ce until 2006.

Martin S. Feldstein, Ph.D.
President and Chief Executive Ofﬁ cer, National Bureau of Economic Research,
and George F. Baker Professor of Economics, Harvard University
Director since 2002
Age 64

Dr. Feldstein is president and chief executive ofﬁ cer of the National Bureau of
Economic Research and the George F. Baker Professor of Economics at Harvard
University. He became an assistant professor at Harvard in 1967 and an associate
professor in 1968. From 1982 through 1984, he served as chairman of the Council
of Economic Advisers and President Ronald Reagan’s chief economic adviser. He
is president of the American Economic Association, a member of the American
Philosophical Society, a corresponding fellow of the British Academy, a fellow of
the Econometric Society, and a fellow of the National Association for Business
Economics. Dr. Feldstein is a member of the executive committee of the Trilateral
Commission, a director of the Council on Foreign Relations, and a member of the
American Academy of Arts and Sciences. He is a director of American Interna-
tional Group, Inc., and HCA Inc.

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Charles E. Golden
Executive Vice President and Chief Financial Ofﬁ cer
Director since 1996
Age 57

Mr. Golden joined the company as executive vice president and chief ﬁ nancial of-
ﬁ cer in 1996. Prior to joining the company, he served as a corporate vice presi-
dent of General Motors Corporation (GM) and chairman and managing director
of Vauxhall Motors Limited, a subsidiary of GM in the United Kingdom from 1993
to 1996. Mr. Golden joined GM in 1970 and held a number of executive positions
in that company’s domestic and international operations. He is a member of the
National Advisory Board of J.P. Morgan Chase & Co.; a director of Hillenbrand In-
dustries, Inc.; chairman of Clarian Health Partners; president of the Crossroads
of America Council, Boy Scouts of America; a director of the Indiana Chamber of
Commerce; vice chairman of The Council of Financial Executives of the Confer-
ence Board; and a member of the Finance Committee of the Indianapolis Mu-
seum of Art.

Ellen R. Marram
Managing Director, North Castle Partners, LLC
Director since 2002
Age 57

Ms. Marram is a managing director at North Castle Partners, LLC. Prior to join-
ing North Castle, she served as the chief executive ofﬁ cer of a start-up B2B ex-
change for the food and beverage industry. From 1993 through 1998, Ms. Marram
was president and chief executive ofﬁ cer of Tropicana and the Tropicana Bever-
age Group. From 1988 to 1993, she was president and chief executive ofﬁ cer of
the Nabisco Biscuit Company, an operating unit of Nabisco, Inc.; from 1987-1988,
was president of Nabisco’s Grocery Division; and from 1970-1986, held a series
of marketing positions at Nabisco/ Standard Brands, Johnson & Johnson, and
Lever Brothers. Ms. Marram is a member of the board of directors of Ford Motor
Company and The New York Times Company as well as several private compa-
nies. She serves on the boards of The New York & Presbyterian Hospital, Lincoln
Center Theater, Families and Work Institute, and Citymeals-on-Wheels.

Sidney Taurel
Chairman of the Board, President, and Chief Executive Ofﬁ cer
Director since 1991
Age 55

Mr. Taurel has been the company’s president since February 1996, chief execu-
tive ofﬁ cer since July 1998, and chairman of the board since January 1999. He
joined the company in 1971 and has held management positions in the company’s
international operations based in São Paulo, Vienna, Paris, and London. Mr.
Taurel served as president of Eli Lilly International Corporation from 1986 until
1991, executive vice president of the Pharmaceutical Division from 1991 until
1993, and executive vice president of the company from 1993 until 1996. He is a
director of IBM Corporation and The McGraw-Hill Companies, Inc.; a member of
the President’s Export Council and the Homeland Security Advisory Council; a
member of the Board of Overseers of the Columbia Business School; a trustee of
the Indianapolis Museum of Art; and a member of The Business Council and The
Business Roundtable.

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HIGHLIGHTS OF THE COMPANY’S CORPORATE GOVERNANCE GUIDELINES

The board of directors has established guidelines that it follows in matters of corporate governance. The following
summary provides highlights of those guidelines. A complete copy of the guidelines is available online at
http://investor.lilly.com/guidelines.cfm.

I. Role of the Board

The directors are elected by the shareholders to oversee the actions and results of the company’s management.
Their responsibilities include:
• providing general oversight of the business
• approving corporate strategy and major management initiatives
• providing oversight of legal and ethical conduct
• nominating, compensating, and evaluating directors
• evaluating board processes and performance
• selecting, evaluating, compensating, and, when necessary, replacing the chief executive ofﬁ cer and compensat-

ing other executive ofﬁ cers.

II. Composition of the Board

Mix of Independent Directors and Ofﬁ cer-Directors
There should always be a substantial majority (75 percent or more) of independent, nonemployee directors. The
chief executive ofﬁ cer should be a board member. Other ofﬁ cers may from time to time be board members, but no
ofﬁ cer other than the chief executive ofﬁ cer should expect to be elected to the board by virtue of his or her ofﬁ ce.

Selection of Director Candidates
The board is responsible for selecting candidates for board membership and for establishing the criteria to be
used in identifying potential candidates. The board delegates the screening process to the directors and corporate
governance committee. For more information on the director nomination process, including the current selection
criteria, see Directors and Corporate Governance Committee Matters on page 63.

Independence Determinations
The board annually determines the independence of directors based on a review by the directors and corporate
governance committee. No director is considered independent unless the board has determined that he or she has
no material relationship with the company, either directly or as a partner, shareholder, or ofﬁ cer of an organization
that has a material relationship with the company. Material relationships can include commercial, industrial, bank-
ing, consulting, legal, accounting, charitable, and familial relationships, among others. The board has adopted cat-
egorical independence standards consistent with the revised New York Stock Exchange listing guidelines adopted
in November 2003 to evaluate the materiality of any such relationship.

Speciﬁ cally, a director is not considered independent if any of the following relationships existed within the previ-
ous three years (or such shorter period as may be provided by the transition rules under the new NYSE listing
guidelines):
• a director who is a current or former employee of Lilly, or whose immediate family member is a current or for-

mer executive ofﬁ cer of Lilly. Temporary service by an independent director as interim chairman or chief execu-
tive ofﬁ cer will not disqualify the director from being independent following completion of that service.

• a director who receives any direct compensation from Lilly other than the director’s normal director compensa-

tion, or whose immediate family member receives more than $100,000 per year in direct compensation from Lilly
other than for service as a non-executive employee.

• a director who is employed (or whose immediate family member is employed as an executive ofﬁ cer) by another

company where any Lilly executive ofﬁ cer serves on that company’s compensation committee.

• a director who is afﬁ liated with or employed in any capacity by Lilly’s independent auditor (currently Ernst & Young
LLP) or whose immediate family member is afﬁ liated with or employed in a professional capacity by the auditor.

• a director who is employed by, who is a 10 percent shareholder of, or whose immediate family member is an

executive ofﬁ cer of a company that makes payments to or receives payments from Lilly for property or services that
exceed the greater of $1 million or 2 percent of that company’s gross revenues in a single ﬁ scal year.

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• a director who is an executive ofﬁ cer of a nonproﬁ t organization that receives grants or contributions from Lilly
in a single ﬁ scal year exceeding the greater of $1 million or 2 percent of that organization’s gross revenues in a
single ﬁ scal year.

Additionally, members of the audit, compensation, and directors and corporate governance committees must meet
all applicable independence tests of the New York Stock Exchange, Securities and Exchange Commission, and
Internal Revenue Service.

The board has determined that all 10 of the nonemployee directors listed on pages 52–55 are independent pursuant
to the above criteria and that the board committee members meet all applicable independence standards.

Director Tenure
Subject to the company’s charter documents, the governance guidelines establish the following expectations for
director tenure:
• Nonemployee directors will resign from the board effective at the annual meeting of shareholders following their

seventy-second birthday.

• Employee directors will resign from the board when they retire or otherwise cease to be active employees of the

company.

• A nonemployee director who retires or changes principal job responsibilities will offer to resign from the board.

The directors and corporate governance committee will assess the situation and recommend to the board
whether to accept the resignation.

III. Director Compensation and Equity Ownership

The directors and corporate governance committee annually reviews board compensation. Any recommendations
for changes are made to the full board by the committee.

Directors should hold meaningful equity ownership positions in the company; accordingly, a signiﬁ cant portion of
overall director compensation is in the form of company equity.

IV. Key Responsibilities of the Board

Selection of Chairman and Chief Executive Ofﬁ cer; Succession Planning
The board customarily combines the roles of chairman and chief executive ofﬁ cer, believing this generally provides
the most efﬁ cient and effective leadership model. The board recognizes that, in certain occasional circumstances,
such as leadership transition, it may be desirable to assign these roles to two different persons for a relatively
short period of time. The chair of the compensation committee recommends to the board an appropriate process
by which a new chairman and chief executive ofﬁ cer will be selected depending on the circumstances at the time.

The independent directors are responsible for overseeing succession planning. The chief executive ofﬁ cer devel-
ops and maintains a process for advising the board on succession planning for the chief executive ofﬁ cer and other
key leadership positions. He or she reviews this plan annually with the independent directors.

Evaluation of Chief Executive Ofﬁ cer
The chair of the compensation committee leads the independent directors annually in assessing the performance
of the chief executive ofﬁ cer. The results of this review are discussed with the chief executive ofﬁ cer and consid-
ered by the compensation committee in establishing his or her compensation for the next year.

Corporate Strategy
Once each year, the board, together with senior management, devotes an extended meeting to discussing and pro-
viding direction for the corporate strategic plan. Throughout the year, signiﬁ cant corporate strategy decisions are
brought to the board for approval.

Code of Ethics
The board has approved the company’s code of ethics, which complies with the requirements of the New York Stock
Exchange and Securities and Exchange Commission. This code is set forth in:

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• The Red Book, a comprehensive code of ethical and legal business conduct applicable to all employees world-

wide and to our board of directors

• the company’s Code of Ethical Conduct for Lilly Financial Management, a supplemental code for our chief ex-
ecutive ofﬁ cer and all members of ﬁ nancial management that recognizes the unique responsibilities of those
individuals in assuring proper accounting, ﬁ nancial reporting, internal controls, and ﬁ nancial stewardship.

Both documents are online at http://investor.lilly.com/code_business_conduct.cfm.

The audit committee and public policy and compliance committee assist in the board’s oversight of compliance
programs with respect to matters covered in the code of ethics.

V. Functioning of the Board

Executive Session of Directors
The independent directors meet alone in executive session after every regularly scheduled board meeting. In addi-
tion, at least twice a year, the independent directors meet in executive session with the chief executive ofﬁ cer.

Presiding Director
The chair of the compensation committee leads the process for selecting and evaluating the chief executive ofﬁ cer.
The chair of the compensation committee also presides at other executive sessions of independent directors unless
the directors decide that, due to the subject matter of the session, another independent director should preside.

Conﬂ icts of Interest
Occasionally a director’s business or personal relationships may give rise to an interest that conﬂ icts, or appears
to conﬂ ict, with the interests of the company. Directors must disclose to the company all relationships that cre-
ate a conﬂ ict or an appearance of a conﬂ ict. The board, after consultation with counsel, takes appropriate steps
to ensure that all directors voting on an issue are disinterested. In appropriate cases, the affected director will be
excused from discussions on the issue.

To avoid any appearance of a conﬂ ict, board decisions on certain matters of corporate governance are made solely
by the independent directors. These include executive compensation and the selection, evaluation, and removal of
the chief executive ofﬁ cer.

Orientation and Continuing Education
A comprehensive orientation process is in place for new directors. In addition, directors receive ongoing continuing
education through educational sessions at meetings, the annual strategy retreat, and periodic mailings between
meetings. The company also affords directors the opportunity to attend external director education programs.

Director Access to Management and Independent Advisers
Independent directors have direct access to members of management whenever they wish. In addition, the inde-
pendent directors and the committees are free to retain their own independent advisers, at company expense,
whenever they wish.

Assessment of Board Processes and Performance
The directors and corporate governance committee annually assesses the performance of the board, its commit-
tees, and board processes. The committee also considers the contributions of individual directors at least every
three years when considering whether to recommend nominating the director to a new three-year term.

VI. Board Committees

Number, Structure, and Independence
The duties and membership of the six board-appointed committees are described below. Only independent direc-
tors may serve on the audit, compensation, directors and corporate governance, and public policy and compliance
committees. All other committees must have a majority of independent directors, and only independent directors
may chair any committee.

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Committee membership and selection of committee chairs are recommended to the board by the directors and
corporate governance committee after consulting the chairman of the board and after considering the desires of
the board members.

Functioning of Committees
Each committee’s charter is reviewed annually by the directors and corporate governance committee. The board
may form new committees or disband a current committee (except the audit, compensation, and directors and
corporate governance committees) as appropriate. The chair of the committee determines the frequency, length,
and agenda of committee meetings.

All six committee charters are available online at http://investor.lilly.com/board-committees.cfm.

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COMMITTEES OF THE BOARD OF DIRECTORS

Audit Committee
The duties of the audit committee are described in the audit committee report found on page 64 of this proxy state-
ment and the committee charter attached as Appendix A.

Directors and Corporate Governance Committee
The duties of the directors and corporate governance committee are described on page 63.

Compensation Committee
• establishes compensation for executive ofﬁ cers
• administers Deferred Compensation Plan, management stock plans, and the company’s cash bonus plan

The compensation committee report is shown on pages 66–68 of this proxy statement.

Public Policy and Compliance Committee
• reviews policies and practices and monitors compliance in areas of legal and social responsibility
• reviews emerging political, social, and public policy issues that may affect the company

Finance Committee
• reviews and makes recommendations regarding capital structure and strategies, including dividends, share

repurchases, capital expenditures, complex business transactions, and borrowings

• oversees ﬁ nancial risk management policies

Science and Technology Committee
• reviews and makes recommendations regarding the company’s strategic research goals and objectives
• reviews new developments, technologies, and trends in pharmaceutical research and development

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MEMBERSHIP AND MEETINGS OF THE BOARD AND ITS COMMITTEES

In 2003, each director attended more than 85 percent of the total number of meetings of the board and the commit-
tees on which he or she serves. Current committee membership and the number of meetings of the full board and
each committee are shown in the table below.

Board

Audit

Compensation

Directors and
Corporate
Governance

Member

Dr. Beering

Sir Winfried Bischoff

Dr. Feldstein

Mr. Fisher

Dr. Gilman

Mr. Golden

Ms. Horn

Ms. Marram

Dr. Prendergast

Sir John Rose

Ms. Seifert

Mr. Taurel

Member

Chair

Member

Chair

Member

Public
Policy and
Compliance

Science and
Technology

Member

Finance

Member

Chair

Member

Chair

Member

Chair

Number of 2003 Meetings

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DIRECTORS’ COMPENSATION

Directors who are employees receive no additional compensation for serving on the board or its committees.
We provide the following annual compensation to directors who are not employees:

Cash compensation
• retainer of $3,750 per month
• $1,600 for each board meeting attended
• $1,600 for each committee or other meeting attended if not held on the same day as a board meeting
• $2,000 to the committee chairpersons for each committee meeting attended as compensation for the chairper-

son’s preparation time

• reimbursement for customary and usual travel expenses

Stock Compensation
• 700 shares of Lilly stock in a deferred stock account in the Lilly Directors’ Deferral Plan (as described below),

payable after service on the board has ended.

• Stock options under the 2002 Lilly Stock Plan for 2,800 shares of Lilly stock. The option price is the fair market

value at the time of grant. The options are exercisable after 3 years and expire after 10 years.

Lilly Directors’ Deferral Plan
This plan allows directors to defer receipt of all or part of their retainer and meeting fees until after their service
on the board has ended. Each director can choose to invest the funds in either of two accounts:
• Deferred Compensation Account. Funds in this account earn interest each year at an annual rate of 120 percent
of the applicable federal long-term rate as established for the preceding December by the U.S. Treasury De-
partment under Section 1274(d) of the Internal Revenue Code. The rate for 2004 is 6.16 percent. The aggregate
amount of interest that accrued in 2003 for the participating directors was $201,055.76.

• Deferred Stock Account. This account allows the director, in effect, to invest his or her deferred cash compen-
sation in Lilly stock. In addition, the annual award of 700 shares to each director noted above is credited to this
account. Funds in this account are credited as hypothetical shares of Lilly stock based on the market price of the
stock at the time the compensation would otherwise have been earned. Hypothetical dividends are “reinvested”
in additional shares based on the market price of the stock on the date dividends are paid. All shares in the de-
ferred stock accounts are hypothetical and are not issued or transferred until the director ends his or her service
on the board or dies.

Both accounts may be paid in a lump sum or in annual installments for up to 10 years. The deferred compensation
account may also be paid in monthly installments for up to 10 years. Amounts in the deferred stock account are
paid in the form of shares of Lilly stock.

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DIRECTORS AND CORPORATE GOVERNANCE COMMITTEE MATTERS

Overview

The directors and corporate governance committee recommends candidates for membership on the board and
board committees. The committee also oversees matters of corporate governance, director independence, direc-
tor compensation, and board performance. The committee’s charter is available online at http://investor.lilly.com/
board-committees.cfm.

All committee members are independent as deﬁ ned in the New York Stock Exchange listing requirements.

Director Nomination Process
The board seeks independent directors who represent a mix of backgrounds and experiences that will enhance the
quality of the board’s deliberations and decisions. Candidates shall have substantial experience with one or more
publicly traded national or multinational companies or shall have achieved a high level of distinction in their chosen
ﬁ elds. Board membership should reﬂ ect diversity in its broadest sense, including persons diverse in geography, gen-
der, and ethnicity. The board is particularly interested in maintaining a mix that includes the following backgrounds:
• active or retired chief executive ofﬁ cers and senior executives, particularly those with experience in operations,

ﬁ nance/banking, and marketing/sales

• international business
• medicine and science
• government and public policy
• information technology.

The board delegates the screening process to the directors and corporate governance committee, which receives
direct input from other board members. Potential candidates are identiﬁ ed from several sources, including:
• recommendations of incumbent directors
• recommendations of management
• recommendations of shareholders
• an independent executive search ﬁ rm retained by the committee to assist in locating candidates meeting the

board’s selection criteria.

The committee employs the same process for evaluating all candidates, including those submitted by shareholders.
The committee initially evaluates the candidate based on publicly available information and any additional information
supplied by the party recommending the candidate. If the candidate appears to satisfy the selection criteria and the
committee’s initial evaluation is favorable, the committee, assisted by management, gathers additional data on the
candidate’s qualiﬁ cations, availability, probable level of interest, and any potential conﬂ icts of interest. If the commit-
tee’s subsequent evaluation continues to be favorable, the candidate is contacted by the chairman of the board and
one or more of the independent directors for direct discussions to determine the mutual levels of interest in pursuing
the candidacy. If these discussions are favorable, the committee makes a ﬁ nal recommendation to the board to nomi-
nate the candidate for election by the shareholders (or to select the candidate to ﬁ ll a vacancy, as applicable).

Process for Submitting Recommendations and Nominations
A shareholder who wishes to recommend a director candidate for evaluation by the committee pursuant to this
process should forward the candidate’s name and information about the candidate’s qualiﬁ cations to the chairman
of the directors and corporate governance committee, in care of the corporate secretary, at Lilly Corporate Center,
Indianapolis, Indiana 46285. The candidate must meet the selection criteria described above and must be willing
and expressly interested in serving on the board.

Under Section 1.9 of the company’s bylaws, a shareholder who wishes to directly nominate a director candidate at the
2005 annual meeting (i.e., to propose a candidate for election who is not otherwise nominated by the board through
the recommendation process described above) must give the company written notice by November 12, 2004. The
notice should be addressed to the corporate secretary at Lilly Corporate Center, Indianapolis, Indiana 46285. The
notice must contain prescribed information about the candidate and about the shareholder proposing the candidate
as described in more detail in Section 1.9 of the bylaws. A copy of the bylaws is available online at http://investor.lilly.
com/bylaws.cfm. The bylaws will also be provided by mail without charge upon request to the corporate secretary.

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AUDIT COMMITTEE MATTERS

Audit Committee Membership

All current members of the audit committee are independent as deﬁ ned in both the New York Stock Exchange list-
ing standards and the Securities and Exchange Commission standards applicable to audit committee members.
The board of directors has determined that Sir Winfried Bischoff is an audit committee ﬁ nancial expert as deﬁ ned
in the rules of the Securities and Exchange Commission.

Audit Committee Report

The audit committee reviews the company’s ﬁ nancial reporting process on behalf of the board. Management has
the primary responsibility for the ﬁ nancial statements and the reporting process, including the systems of inter-
nal controls and disclosure controls. In this context, we have met and held discussions with management and the
independent auditors. Management represented to us that the company’s consolidated ﬁ nancial statements were
prepared in accordance with generally accepted accounting principles, and we have reviewed and discussed the
audited ﬁ nancial statements and related disclosures with management and the independent auditors, including a
review of the signiﬁ cant management judgments underlying the ﬁ nancial statements and disclosures.

The independent auditors report to us and to the board. We have sole authority to appoint (subject to shareholder
ratiﬁ cation) and to terminate the engagement of the independent auditors.

We have discussed with the independent auditors matters required to be discussed by Statement on Auditing
Standards No. 61 (Communication With Audit Committees), including the quality, not just the acceptability, of
the accounting principles, the reasonableness of signiﬁ cant judgments, and the clarity of the disclosures in the
ﬁ nancial statements. In addition, we have received the written disclosures and the letter from the independent
auditors required by the Independence Standards Board Standard No. 1 (Independence Discussions With Audit
Committees) and have discussed with the independent auditors the auditors’ independence from the company
and its management. In concluding that the auditors are independent, we determined, among other things, that
the nonaudit services provided by Ernst & Young (as described below) were compatible with their independence.
Consistent with the requirements of the Sarbanes-Oxley Act of 2002, we have adopted additional policies to ensure
the independence of the independent auditors, such as prior committee approval of nonaudit services and required
audit partner rotation.

We discussed with the company’s internal and independent auditors the overall scope and plans for their re-
spective audits. We periodically meet with the internal and independent auditors, with and without management
present, to discuss the results of their examinations, their evaluations of the company’s internal controls, and the
overall quality of the company’s ﬁ nancial reporting. We also periodically meet in executive session.

In reliance on the reviews and discussions referred to above, we recommended to the board (and the board subse-
quently approved the recommendation) that the audited ﬁ nancial statements be included in the company’s annual
report on Form 10-K for the year ended December 31, 2003, for ﬁ ling with the Securities and Exchange Commis-
sion. We have also appointed the company’s independent auditors, subject to shareholder ratiﬁ cation.

Audit Committee
Sir Winfried Bischoff, Chair
Martin S. Feldstein, Ph.D.
Franklyn G. Prendergast, M.D., Ph.D.
Kathi P. Seifert

Services Performed by the Independent Auditor
The audit committee preapproves all audit and nonaudit services performed by the independent auditor in order to
assure that the provision of such services does not impair the auditor’s independence. The committee’s policy and
procedures are as follows:
• All audit services must be preapproved by the committee. The committee approves the annual audit services

engagement and, if necessary, any changes in terms, conditions, and fees resulting from changes in audit scope,

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company structure, or other matters. The committee may also grant preapproval for other audit services, which are
those services that only the independent auditor reasonably can provide.

• Audit-related services are assurance and related services that are reasonably related to the performance of the

audit, and that are traditionally performed by the independent auditor. The committee believes that the provision of
these services does not impair the independence of the auditor. All audit-related services must be preapproved by
the committee.

• All tax services must be separately preapproved by the committee. The committee believes that, in appropriate

cases, the independent auditor can provide tax compliance services, tax planning, and tax advice without impairing
the auditor’s independence.

• Nonaudit services classiﬁ ed as “all other services” must be separately preapproved by the committee. The
committee may approve such services if (i) the services are permissible under SEC rules, (ii) the committee
believes the provision of the services would not impair the independence of the auditor, and (iii) management
believes that the auditor is the best choice to provide the service.

• Process. At the beginning of each audit year, management requests prior committee approval of the annual audit,
statutory audits, and quarterly reviews for the upcoming audit year as well as any other engagements known at
that time. Management will also present at that time an estimate of all fees for the upcoming audit year. As speciﬁ c
engagements are identiﬁ ed thereafter, they are brought forward to the committee for approval. To the extent
approvals are required between regularly scheduled committee meetings, preapproval authority is delegated to the
committee chair.

For each engagement, management provides the committee with information about the services and fees sufﬁ -
ciently detailed to allow the committee to make an informed judgment about the nature and scope of the services
and the potential for the services to impair the independence of the auditor.

After the end of the audit year, management provides the committee with a summary of the actual fees incurred for
the completed audit year.

Independent Auditor Fees
The following table shows the fees incurred for services rendered on a worldwide basis by Ernst & Young LLP, the
company’s independent auditor, in 2003 and 2002. All such services were preapproved by the committee in accor-
dance with the preapproval policy.

Audit Fees
•
•
•

Annual audit of consolidated and subsidiary ﬁ nancial statements
Reviews of quarterly ﬁ nancial statements
Other services normally provided by auditor in connection with statutory and
regulatory ﬁ lings

Audit-Related Fees

•

Assurance and related services reasonably related to the performance of the
audit or reviews of the ﬁ nancial statements:

—2003: primarily related to internal control reviews, employee beneﬁ t plan

audits, and accounting consultations

—2002: primarily related to system control assessments and accounting

consultations

Tax Fees

•
•

2003: primarily related to tax planning and various compliance services
2002: tax assistance provided to company employees living outside their country

of permanent residence and assistance with tax planning

All Other Fees

Total

2003 (millions)

2002 (millions)

$3.9

$3.2

0.9

0.8

2.4

6.2

None

$7.2

None

$10.2

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EXECUTIVE COMPENSATION

Compensation Committee Report

The following is a report of the compensation committee of the board regarding executive compensation. The
committee’s membership and duties are described on page 60–61.

Executive Compensation Policy
Philosophy. The compensation committee bases its executive compensation policy on the same principles that
guide the company in establishing all its compensation programs. We design programs to attract, retain, and
motivate highly talented individuals at all levels of the organization while balancing the interests of shareholders.
In particular:
• We base compensation on the level of job responsibility, individual performance, and company performance. As
employees progress to higher levels in the organization, an increasing proportion of their pay is linked to com-
pany performance.

• We reﬂ ect in our compensation the value of the job in the marketplace. To attract and retain a highly skilled work

force, we must remain competitive with the pay of other premier employers who compete with us for talent.

• To assure our employees’ interests are aligned with those of our shareholders, we provide employees worldwide

at all levels of the organization with the opportunity for equity ownership.

• We develop and administer our compensation programs to foster the long-term focus required for success in our

industry.

The program consists of both annual and long-term components, which are considered together in assessing
whether the program is attaining its objectives.

Methodology. We consider various measures of company and industry performance, including sales, earnings per
share, total market value, total shareholder return, and economic value added (EVA®). These data assist us in exer-
cising judgment in establishing total compensation ranges. We do not assign these performance measures relative
weights. Instead, we make a subjective determination after considering all such measures collectively.

We also compare, or benchmark, our programs with other global pharmaceutical companies of comparable size
and stature to the company. For this benchmarking, we use the peer group identiﬁ ed on page 73. We compare the
executive compensation programs as a whole, and we also compare the pay of individual executives if we believe
the jobs are sufﬁ ciently similar to make the comparison meaningful.

We use the peer group data primarily to ensure that the executive compensation program as a whole is within the
broad middle range of comparative pay of the peer group companies when the company achieves the targeted per-
formance levels. We do not target a speciﬁ c position in the range of comparative data for each individual or for each
component of compensation. We establish individual amounts in view of the comparative data and such other factors
as level of responsibility, prior experience, and our subjective judgment as to individual contribution. We do not apply
formulas or assign these factors speciﬁ c mathematical weights; instead, we exercise judgment and discretion.

We also retain an independent compensation consultant to assist us in evaluating our executive compensation pro-
grams. The use of an independent consultant provides additional assurance that our programs are reasonable and
consistent with the company’s objectives.

Components of Executive Compensation for 2003
Annual Compensation. Annual cash compensation for 2003 consisted of base salary and a cash bonus.
• We determined base salaries based on company and individual performance for the previous year, internal rela-
tivity, and market conditions, including pay at the peer group companies. As noted above, we used the peer group
and other market data to test for reasonableness and competitiveness of base salaries, but we also exercised
subjective judgment in view of our compensation objectives. Following a freeze on salary increases for all man-
agement employees in 2002, we approved merit increases for 2003.

• Cash bonuses for management have historically been determined under the EVA® Bonus Plan (EVA Plan), a for-

mula-based plan based on the concept of Economic Value Added. In basic terms, EVA is after-tax operating proﬁ t
less the annual total cost of capital. Under the EVA Plan, the size of bonuses varied directly with the amount by

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which after-tax operating proﬁ t exceeded the cost of capital. If the company failed to achieve the target EVA, no
bonus was paid under the EVA Plan.

Under the terms of the EVA Plan, no bonuses were paid for either 2002 or 2003. However, we determined that it
would be in the company’s best interest to pay a one-time discretionary bonus to management and executives for
2003 performance in order to maintain the overall competitiveness of our compensation programs and to attract,
retain, and motivate our management and technical talent. For nonexecutive management, we approved a one-time
bonus payout equal to 85 percent of the normal EVA bonus target. For executive ofﬁ cers, we awarded a bonus equal
to 75 percent of the normal EVA bonus target. In approving these bonuses, we took into account the following:
• Given the 2002 freeze on merit increases, and the absence of cash or stock bonus payouts for 2002, a second con-
secutive year with no cash bonus would signiﬁ cantly strain our ability to attract, motivate and retain top talent.

• The company achieved a number of important business objectives in 2003, including:

—achieving strong sales growth of 14 percent
—meeting external earnings expectations for the year, despite signiﬁ cantly increased investments in R&D, sales

and marketing, and manufacturing

—successfully launching three new products: Strattera®, Forteo®, and Cialis®
—preparing for the launch in 2004 of up to four more new products, as well as a new indication and a new formu-

lation for Zyprexa

—making signiﬁ cant progress in addressing manufacturing quality issues in its Indianapolis facilities, thus

clearing a key regulatory hurdle for future product approvals.

Long-Term Incentives. We normally employ two forms of long-term equity incentives granted under the 2002 Lilly
Stock Plan: stock options and performance awards. These incentives foster the long-term perspective necessary
for continued success in our business. They also ensure that our leaders are properly focused on shareholder
value. Stock options and performance awards have traditionally been granted broadly and deeply within the organi-
zation, with approximately 5,300 management and professional employees now participating.
• Stock options align employee incentives with shareholders because options have value only if the stock price

increases over time. Our 10-year options, granted at the market price on the date of grant, ensure that employees
are oriented to growth over the long term. In addition, options help retain key employees because they typically
cannot be exercised for three years and, if not exercised, are forfeited if the employee leaves the company before
retirement. The three-year vesting also helps keep employees focused on long-term performance. We granted
stock options in 2003 in amounts essentially the same as the previous year.

• Performance awards provide employees shares of Lilly stock if certain company performance goals are achieved.

The awards, normally granted annually, are structured as a schedule of shares of Lilly stock based on the
company’s achievement of speciﬁ c earnings-per-share (EPS) levels over speciﬁ ed time periods of one or more
years. We granted performance awards for 2003 performance, but the growth in EPS for the year was not sufﬁ cient
for a payout. For the award period January 1, 2004, through December 31, 2004, performance awards may be
earned from zero to 200 percent of the target amount depending on EPS growth. Any payout to executive ofﬁ cers
will be payable in Lilly restricted stock. If a payout is earned for 2004, the shares will be paid in early 2005 and will
remain restricted until early 2006.

• Share retention guidelines help foster a focus on long-term growth. We expect our executive ofﬁ cers to retain
all net shares received from stock options and performance awards for at least one year. Consistent with this
objective, performance award shares earned for 2004 performance will be issued in the form of restricted stock
that is subject to forfeiture if the executive leaves the company prior to early 2006 for any reason other than death,
disability, or retirement.

Deductibility Cap on Executive Compensation. Under U.S. federal income tax law, the company cannot take a tax
deduction for certain compensation paid in excess of $1 million to the ﬁ ve executive ofﬁ cers listed below. However,
performance-based compensation, as deﬁ ned in the tax law, is fully deductible if the programs are approved by
shareholders and meet other requirements. Our policy is to qualify our incentive compensation programs for full
corporate deductibility to the extent feasible and consistent with our overall compensation goals. The company has
taken steps to qualify compensation under the EVA Plan, as well as stock options and performance awards under its
management stock plans, for full deductibility as “performance-based compensation.” We may make payments that
are not fully deductible if, in our judgment, such payments are necessary to achieve our compensation objectives, as
was the case with the discretionary bonus payment made to executive ofﬁ cers for 2003 performance as described
above. The incremental taxes payable because of the lack of full deductibility for this bonus will not be material.

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Chief Executive Ofﬁ cer Compensation for 2003
In establishing Mr. Taurel’s compensation for 2003, we applied the principles outlined above in the same manner
as they were applied to the other executives. We compared company performance with that of the peer group com-
panies, including EPS growth, EVA, and total shareholder return. We did not assign these performance measures
relative weights but rather made a subjective determination after considering the data collectively. In addition,
consistent with our annual process, in an executive session including all independent directors, we assessed Mr.
Taurel’s 2002 performance. We considered the company’s and Mr. Taurel’s accomplishment of objectives that had
been established at the beginning of the year and our own subjective assessment of his performance.

In recognition of his strong leadership and many contributions in a challenging year for the company, we established
Mr. Taurel’s salary at $1.43 million. Because Mr. Taurel chose to accept only $1.00 in salary for 2002, the salary
growth rate in 2003 is not meaningful. However, the 2003 salary amount is 4 percent higher than his 2001 salary.

Consistent with past practice and to maintain internal relativity, we established Mr. Taurel’s 2003 target bonus
under the EVA Plan at 110 percent of his base salary. These amounts restored Mr. Taurel’s competitive position for
both salary and cash bonus within the broad middle range of peer group chief executives. There was no EVA bonus
payout for 2003, but the committee decided to award a discretionary bonus to all members of management, includ-
ing Mr. Taurel, for the reasons described earlier in this report under Annual Compensation—Cash Bonuses. As
noted there, bonuses for the executive ofﬁ cers were 75 percent of target EVA amounts.

In 2003, Mr. Taurel received a stock option grant for 350,000 shares, the same size as he received in the prior year. The
option shares vest after three years and expire after 10 years. In late 2002, we granted Mr. Taurel a performance award
to be earned based on 2003 EPS growth. However, the company’s EPS growth for 2003 was insufﬁ cient for a payout. In
late 2003, we granted Mr. Taurel a performance award to be earned based on 2004 EPS growth. If the growth target is
achieved, he will receive 28,000 shares (before taxes) in 2005. Consistent with the other executive ofﬁ cers, any shares
paid under this performance award will be in the form of restricted stock.

In determining the size of the stock option and performance award grants, we took into consideration internal rela-
tivity, peer group data, and the size of grants previously made to Mr. Taurel.

Compensation Committee
Steven C. Beering, M.D., Chair
George M.C. Fisher
Karen N. Horn, Ph.D.
Ellen R. Marram

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Summary Compensation Table

Name and
Principal Position

Year

Annual Compensation

Sidney Taurel
Chairman of the Board,
President, and
Chief Executive Ofﬁ cer

Gerhard N. Mayr
Executive Vice President,
Pharmaceutical Operations

Charles E. Golden
Executive Vice President
and Chief Financial Ofﬁ cer

John C. Lechleiter, Ph.D.
Executive Vice President,
Pharmaceutical Products
and Corporate Development

Pedro P. Granadillo
Senior Vice President

2003
2002
2001

Salary
($)

Bonus (2)
($)

Other Annual
Compensation
($)

1,432,860

1 (6)

1,391,100

1,193,595
0
474,366

126,561 (3)
57,299
269,808

858,510
820,080
820,080

789,540
789,540
789,540

725,625
675,000
675,000

661,380
642,120
642,120

490,118
0
190,669

444,117
0
183,569

417,657
0
146,475

375,638
0
139,341

11,258
6,924
1,610

6,492
14,852
74,218

6,249
9,248
42,322

24,478
43,206
160,969

Long-Term Compensation (1)

Awards

Number of
Securities
Underlying Options
Granted

350,000
350,000
175,000

120,000
120,000
60,000

120,000
120,000
70,000

100,000
100,000
60,000

Payouts

Long-Term
Incentive
Plan Payout
($)

0 (4)
0 (4)

2,149,000

0 (4)
0 (4)

690,750

0 (4)
0 (4)

690,750

0 (4)
0 (4)

429,800

0 (4)
0 (4)

560,275

All Other
Compensation
($)

68,777 (5)
142,362
41,732

41,208 (5)
24,601
138,917

37,898 (5)
23,686
23,686

34,840 (5)
20,250
72,764

31,746 (5)
19,264
19,264

(1) The company’s stock plans do not provide for stock appreciation rights. Accordingly, none were granted during

the years indicated. In addition, no restricted stock was granted during the years indicated in the table. Mr. Mayr
holds 13,000 shares of restricted stock valued at $914,290 as of December 31, 2003. The vesting of these shares
has been accelerated from December 31, 2004, to February 2, 2004. In accordance with the terms of the original
grant, the company will reimburse Mr. Mayr for the associated U.S. federal income tax of approximately $603,320.

(2) Represents the individual’s declared bonus for 2001 and 2002, when bonuses were paid under the EVA Plan,

based on the company’s actual EVA performance for the year. Under the EVA Plan, a portion of an individual’s
declared bonus may be carried over to subsequent years. As a result, actual payments with respect to a year
may differ from the declared bonus. There was no bonus awarded under the EVA Plan to executive ofﬁ cers for
2003 performance. The Compensation Committee awarded a bonus to executive ofﬁ cers equal to 75 percent of
the normal EVA bonus target as described in the Compensation Committee report.

(3) Of Mr. Taurel’s total, $60,725 represents personal use of the company aircraft. Mr. Taurel is required to travel

on the company aircraft for security reasons.

(4) There was no payment in February 2003 under the performance award program for the period January 1, 2001,
through December 31, 2002. Likewise, there was no payment in February 2004 for the performance period
January 1, 2003, through December 31, 2003.

(5) Company contribution to the named individual’s account in the Savings Plan. In light of the Prozac patent expira-
tion, the company contributed only the minimum amount required by the Savings Plan in 2001, 2002, and 2003.

(6) During the 2002 calendar year, Mr. Taurel chose to accept an annual salary of $1.00 as a reﬂ ection of his conﬁ -
dence in and commitment to the company during this period of transition. Had Mr. Taurel not taken this action,
his annual base salary would have been $1,391,100 for 2002.

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Option Shares Granted in the Last Fiscal Year (1)

Name

Sidney Taurel

Gerhard N. Mayr

Charles E. Golden

John C. Lechleiter, Ph.D.

Pedro P. Granadillo

Individual Grants

Number of Securities
Underlying
Options Granted

% of Total Option Shares
Granted to Employees in
Fiscal Year

Exercise or
Base Price
Per Share (2)

Expiration Date

Grant Date
Present
Value (3)

350,000

120,000

100,000

2.24

0.77

0.64

$57.85

2/15/13

$7,161,000

2/15/13

$2,455,200

2/15/13

$2,455,200

2/15/13

$2,455,200

2/15/13

$2,046,000

(1) The company’s stock plans do not provide for stock appreciation rights. Accordingly, none were granted in 2003.

(2) Options are granted at the market price of company common stock on the date of grant. Options are exercisable

three years after their grant date.

(3) These values were established using the Black-Scholes stock option valuation model. Assumptions used to

calculate the grant date present value of option shares granted during 2003 were in accordance with SFAS 123
as follows:

(a) Expected Volatility—The standard deviation of the continuously compounded rates of return calculated on
the average daily stock price over a period of time immediately preceding the grant and equal in length to
the expected life. The volatility was 35.10 percent.

(b) Risk-Free Interest Rate—The rate available at the time the grant was made on zero-coupon U.S. gov-
ernment issues with a remaining term equal to the expected life. The risk-free interest rate was 3.32
percent.

period of time immediately preceding the grant date equal in length to the expected life of the grant.
(d) Expected Life—The expected life of the grant was seven years, calculated based on the historical expect-

ed life of previous grants.

(e) Forfeiture Rate— Under SFAS 123, forfeitures may be estimated or assumed to be zero. The forfeiture

rate was assumed to be zero, based on the immateriality of actual calculated forfeiture rates.

Aggregate Option Shares Exercised in the Last Fiscal Year and Fiscal Year-End Option Values (1)

Name

Sidney Taurel

Gerhard N. Mayr

Charles E. Golden

Number of
Shares
Acquired
On Exercise

Value Realized

Number of
Securities Underlying
Unexercised Options at
Fiscal Year-End

Value of
Unexercised,
In-the-Money Options
at Fiscal Year-End (2)

87,162

$4,445,487

2,161,521

351,317

$26,210,573

$4,368,000

Exercisable

Unexercisable

Exercisable

Unexercisable

John C. Lechleiter, Ph.D.

25,180

$1,372,625

Pedro P. Granadillo

-0-

534,684

758,683

479,521

659,411

240,000

$10,431,070

$1,497,600

121,317

$8,537,800

$1,497,600

$2,211,353

$1,497,600

101,317

$10,082,847

$1,248,000

(1) The company’s stock plans do not provide for stock appreciation rights. Accordingly, no stock appreciation

rights were exercised during 2003 and none were outstanding on December 31, 2003.

(2) Represents the amount by which the market price of Lilly stock exceeded the exercise prices of unexercised op-

tions held by the named individuals on December 31, 2003.

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Retirement Plan

Pension Plan Table

Average Annual
Earnings (Highest
5 of Last 10 Years)

$ 500,000

1,000,000

1,500,000

2,000,000

2,500,000

3,000,000

3,500,000

4,000,000

4,500,000

5,000,000

5,500,000

Years of Service

$ 134,830

$ 168,550

$ 202,260

$ 235,970

$ 243,300

275,270

415,705

556,140

696,575

837,000

977,435

1,117,870

1,258,310

1,398,745

1,539,170

344,100

519,635

695,185

870,720

1,046,270

1,221,805

1,397,350

1,572,890

1,748,435

1,923,970

412,910

623,555

834,215

1,044,865

1,255,510

1,466,160

1,676,810

1,887,455

2,098,116

2,308,765

481,730

727,490

973,250

1,219,010

1,464,770

1,710,530

1,956,290

2,202,050

2,447,810

2,693,555

481,730

727,490

973,705

1,219,010

1,464,770

1,710,530

1,956,290

2,202,050

2,447,810

2,693,555

486,610

729,910

973,705

1,219,010

1,464,770

1,710,530

1,956,290

2,202,050

2,447,810

2,693,555

The named executive ofﬁ cers will, upon retirement, be eligible for beneﬁ ts under The Lilly Retirement Plan (retire-
ment plan). The above table sets forth a range of annual retirement beneﬁ ts for various levels of average annual
earnings and years of service, assuming the employee retires at age 65 with a 50 percent survivor income beneﬁ t.
The retirement plan beneﬁ ts shown in the table are generally paid as a monthly annuity for the life of the retiree.
The amounts shown in the table are not subject to reduction for social security beneﬁ ts or any other offset amounts
except that the ultimate pension beneﬁ ts for Mr. Golden will be reduced by the amount of the pension payments he
receives from his previous employer. For the purpose of determining the annual beneﬁ t from the Pension Plan Table,
one calculates the average of the annual earnings for the highest 5 out of the last 10 years of service (“average an-
nual earnings”). Annual earnings covered by the retirement plan consist of salary, bonus, and, for years prior to 2003,
long-term incentive plan payouts as set forth in the Summary Compensation Table on page 20 but calculated for the
amount of bonus paid (rather than credited) and for the year in which earnings are paid (rather than earned or cred-
ited). For purposes of determining beneﬁ ts under the retirement plan, Mr. Taurel is currently credited with 32 years
of service, and his current average annual earnings are $4,618,368. Following his retirement in 2004, Mr. Mayr will
receive an annual retirement beneﬁ t of $915,478. Beginning at age 62, Mr. Mayr will receive an additional $1,400 per
month, which is the estimated amount Mr. Mayr would have received as a social security beneﬁ t had he worked in the
United States for more than 40 calendar quarters. His retirement beneﬁ ts will include medical coverage beginning at
age 65, under which the company will reimburse the portion of his medical expenses that would typically be covered
by Medicare had he worked in the United States for more than 40 calendar quarters and related income taxes, if any,
attributable to such beneﬁ t. Mr. Golden, who is credited with 34 years, received additional service credit when be be-
gan his employment in 1996. His retirement beneﬁ ts will include standard retiree medical beneﬁ ts. His current aver-
age annual earnings are $2,486,772. Dr. Lechleiter is credited with 24 years, and his current average annual earnings
are $1,416,888. Mr. Granadillo is credited with 34 years, and his current average annual earnings are $1,856,712.

Section 415 of the Internal Revenue Code (Code) generally places a limit of $165,000 on the amount of annual pen-
sion beneﬁ ts that may be paid at age 65 from a plan such as the retirement plan. Under an unfunded plan adopted
in 1975, however, the company will make payments as permitted by the Code to any employee who is a participant
in the retirement plan in an amount equal to the difference, if any, between the beneﬁ ts that would have been pay-
able under the plan without regard to the limitations imposed by the Code and the actual beneﬁ ts payable under
the plan as so limited.

Change-in-Control Severance Pay Arrangements

The company has adopted a Change-in-Control Severance Pay Program (program) covering most employees of the
company and its subsidiaries, including the company’s executive ofﬁ cers. In general, the program would provide
severance payments and beneﬁ ts for eligible employees and executive ofﬁ cers in the event their employment is ter-
minated under certain circumstances within ﬁ xed periods of time following a change in control. A change in control
71

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would occur if 15 percent or more of the company’s voting stock were acquired by an entity other than the company,
a subsidiary, an employee beneﬁ t plan of the company, or Lilly Endowment, Inc. There are additional conditions that
could result in a change-in-control event. The program may not be amended by the board, whether prior to or fol-
lowing a change in control, in any manner adverse to a participant without his or her prior written consent.

Under the portion of the program covering the named executive ofﬁ cers, each would be entitled to severance pay-
ments and beneﬁ ts in the event that his or her employment is terminated following a change in control (i) without
cause by the company; (ii) for good reason by the executive ofﬁ cer, each as is deﬁ ned in the program; or (iii) for a
limited period of time, for any reason, by the executive ofﬁ cer. In such case, the executive ofﬁ cer would be entitled
to a severance payment equal to three times his or her current annual cash compensation. Additional beneﬁ ts
would include a pension supplement and full and immediate vesting of all stock options and other equity incentives.
In the event that any payments made or beneﬁ ts realized in connection with the change in control would be subject
to the excise tax imposed under Section 4999 of the Internal Revenue Code as a result of the aggregate compensa-
tion payments and beneﬁ ts made to the individual, under the program or otherwise, the company would cover the
cost of the excise tax.

Employment Agreement

At the company’s request, Mr. Mayr postponed his retirement in order to continue leading the company’s sales and
marketing efforts as the company prepared for and implemented launches of several important new products. As
consideration, we extended the expiration of his 1993 stock option from April 21, 2003, to April 21, 2005. In addition,
prior to his retirement in 2004 Mr. Mayr received a cash payment of $725,000, reimbursement of the associated
U.S. federal income tax of approximately $494,510, and a nonqualiﬁ ed stock option for 60,000 shares vesting in
March 2004 with a 10-year term. The company has agreed to lease a company-owned apartment to Mr. Mayr for up
to 12 months following his retirement. He will reimburse the company for the company’s entire cost of this apart-
ment, currently approximately 11,700 GBP (approximately $21,350) per month.

PERFORMANCE GRAPH

This graph compares the return on Lilly stock with that of the Standard & Poor’s 500 Stock Index and our peer
group* for the years 1999 through 2003. The graph assumes that, on December 31, 1998, a person invested $100
each in Lilly stock, the S&P 500 Stock Index, and the peer group’s common stock. The graph measures total share-
holder return, which takes into account both stock price and dividends. It assumes that dividends paid by a com-
pany are reinvested in that company’s stock.

Comparison of Five-Year Cumulative Total Return Among Lilly, S&P 500 Stock Index, and Peer Group*

Value of $100 invested on last business day of 1998

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Lilly

S&P 500

Peer Group

1998

$100.00

1999

$ 75.80

$121.01

$ 87.41

2000

$107.43

$109.99

$112.10

2001

$91.99

$96.98

$97.01

2002

$75.88

$75.59

$75.52

2003

$85.83

$97.24

$83.00

* We constructed the peer group as the industry index for this graph. It comprises the eight companies in the

pharmaceutical industry that we use to benchmark compensation of executive ofﬁ cers. The companies are Abbott
Laboratories; Bristol-Myers Squibb Company; Glaxo SmithKline (including the results of SmithKline Beecham
plc up to the time of its merger with Glaxo Holdings plc); Johnson & Johnson; Merck & Co.; Pﬁ zer, Inc. (including
the results of Warner Lambert Company and Pharmacia Corporation to the time of their mergers with Pﬁ zer);
Schering-Plough Corporation; and Wyeth (formerly American Home Products Corporation).

OWNERSHIP OF COMPANY STOCK

Common Stock Ownership by Directors and Executive Ofﬁ cers

The following table sets forth the number of shares of company common stock beneﬁ cially owned by the directors,
the named executive ofﬁ cers, and all directors and executive ofﬁ cers as a group, as of February 2, 2004.

Name of Individual or Identity of Group

Shares Owned Beneﬁ cially (1)

Steven C. Beering, M.D.

Sir Winfried F. W. Bischoff

Martin S. Feldstein, Ph.D.

George M. C. Fisher

Alfred G. Gilman, M.D., Ph.D.

Charles E. Golden

Pedro P. Granadillo

Karen N. Horn, Ph.D.

John C. Lechleiter, Ph.D.

Ellen R. Marram

Gerhard N. Mayr

Franklyn G. Prendergast, M.D., Ph.D.

Sir John Rose

Kathi P. Seifert

Sidney Taurel

All directors and executive ofﬁ cers as a group (16 persons)

26,791

4,889

2,422

16,077

8,206

39,102 (2)

207,868 (3)

21,731

125,893 (4)

2,422

100,483 (5)

13,269

128

12,515

783,551 (6)

1,511,910

(1) Unless otherwise indicated in a footnote, each person listed in the table possesses sole voting and sole invest-
ment power with respect to the shares shown in the table to be owned by that person. The shares shown do
not include the following shares that may be purchased pursuant to stock options that are exercisable within
60 days of February 2, 2004: Dr. Beering, 2,800 shares; Sir Winfried Bischoff, 2,800 shares; Mr. Fisher, 2,800
shares; Dr. Gilman, 2,800 shares; Mr. Golden, 758,683 shares; Mr. Granadillo, 659,411 shares; Ms. Horn, 2,800
shares; Dr. Lechleiter, 479,521 shares; Mr. Mayr, 594,684 shares; Dr. Prendergast, 2,800 shares; Ms. Seifert,
2,800 shares; Mr. Taurel, 2,161,521 shares; and all directors and executive ofﬁ cers as a group, 5,456,338 shares.
The shares shown include, in the case of employees of the company, shares credited to the accounts of the
employees under the Savings Plan. In the case of nonemployee directors, the shares shown above include the
following shares credited to the directors’ accounts under the Lilly Directors’ Deferral Plan: Dr. Beering, 24,151;
Sir Winfried Bischoff, 2,889; Dr. Feldstein, 1,422; Mr. Fisher, 6,077; Dr. Gilman, 8,206; Ms. Horn, 19,676; Ms. Mar-
ram, 1,422; Dr. Prendergast, 13,269; Sir John Rose, 128; and Ms. Seifert, 9,383. See pages 60–61 for a descrip-
tion of that plan. No person listed in the table owns more than 0.0697 percent of the outstanding common stock
of the company. All directors and executive ofﬁ cers as a group own 0.135 percent of the outstanding common
stock of the company.

(2) The shares shown for Mr. Golden include 971 shares credited to his account under the Savings Plan.
(3) The shares shown for Mr. Granadillo include 18,574 shares credited to his account under the Savings Plan and
895 shares that are owned by a family foundation for which he is a director. Mr. Granadillo has shared voting
power and shared investment power over the shares held by the foundation.

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(4) The shares shown for Dr. Lechleiter include 10,946 shares credited to his account under the Savings Plan and
12,151 shares that are owned by a family foundation for which he is a director. Dr. Lechleiter has shared voting
power and shared investment power over the shares held by the foundation.

(5) The shares shown for Mr. Mayr include 9,623 shares credited to his account under the Savings Plan.
(6) The shares shown for Mr. Taurel include 14,495 shares credited to his account under the Savings Plan.

Principal Holders of Stock

To the best of the company’s knowledge, the only beneﬁ cial owners of more than ﬁ ve percent of the outstanding
shares of the company’s common stock are Lilly Endowment, Inc. (the “Endowment”) and Capital Research and
Management Company. The following table sets forth information regarding this ownership:

Name and Address

Lilly Endowment, Inc.
2801 North Meridian Street
Indianapolis, Indiana 46208

Number of Shares
Beneﬁ cially Owned

154,120,804
(as of February 2, 2004)

Capital Research and Management Company
333 South Hope Street
Los Angeles, California 90071

66,757,200
(as of December 31, 2003)

Percent of
Class

13.71%

5.9%

The Endowment has sole voting and sole investment power with respect to its shares. The board of directors of the
Endowment is composed of Mr. Thomas M. Lofton, chairman; Mr. N. Clay Robbins, president; Mrs. Mary K. Lisher;
Drs. Otis R. Bowen, William G. Enright, and Earl B. Herr, Jr.; and Messrs. Daniel P. Carmichael, Eli Lilly II, and Eu-
gene F. Ratliff. Each of the directors is a shareholder of the company.

Capital Research and Management Company acts as investment adviser to various registered investment compa-
nies. It has no voting power and sole investment power with respect to its shares.

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ITEMS OF BUSINESS TO BE ACTED UPON AT THE MEETING

Item 1. Election of Directors

Under the company’s articles of incorporation, the board is divided into three classes with approximately one-third
of the directors standing for election each year. The term for directors elected this year will expire at the annual
meeting of shareholders held in 2007. Each of the nominees listed below has agreed to serve that term. If any
director is unable to stand for election, the board may, by resolution, provide for a lesser number of directors or
designate a substitute. In the latter event, shares represented by proxies may be voted for a substitute director.

The board recommends that you vote FOR each of the following nominees:
• Steven C. Beering, M.D.
• Sir Winfried Bischoff
• Franklyn G. Prendergast, M.D., Ph.D.
• Kathi P. Seifert

Biographical information about these nominees can be found on pages 52–53 of this proxy statement.

Item 2. Proposal To Ratify the Appointment of Principal Independent Auditors

The audit committee has appointed the ﬁ rm of Ernst & Young LLP as principal independent auditors for the com-
pany for the year 2004. In accordance with the bylaws, this appointment is being submitted to the shareholders for
ratiﬁ cation. Ernst & Young served as the principal independent auditors for the company in 2003. Representatives
of Ernst & Young are expected to be present at the annual meeting and will be available to respond to appropriate
questions. Those representatives will have the opportunity to make a statement if they wish to do so.

The board recommends that you vote FOR ratifying the appointment of Ernst & Young LLP as principal indepen-
dent auditors for 2004.

Item 3. To Approve the Eli Lilly and Company Bonus Plan

The board of directors has approved a new annual cash bonus plan, the Eli Lilly and Company Bonus Plan, effective
January 1, 2004. It replaces both the prior management and executive bonus plan (the Eli Lilly and Company EVA
Bonus Plan) and the company’s principal bonus program for nonmanagement employees.

The board recommends that you vote FOR approval of the Eli Lilly and Company Bonus Plan.

Shareholder approval will allow payments under the plan to be fully tax-deductible by the company under Section
162(m) of the Internal Revenue Code. Section 162(m) could limit the company’s tax deduction for compensation
paid to top executives to $1 million each unless compensation in excess of that amount is determined using perfor-
mance measures approved by a committee of outside directors and approved by the shareholders.

Purpose of the Plan
The purpose of the plan is to motivate superior performance and teamwork by employees at all levels of the com-
pany by linking annual cash bonuses to important corporate performance measures. Bonus payments are linked
directly to both individual and corporate performance. Exceptional performance by individuals and the company
will lead to increases in bonuses, and shortfalls in performance will lead to bonus reductions.

Principal Features of the Plan
Following is a summary of the material features of the plan. It is qualiﬁ ed by reference to the full text of the plan,
which is attached as Appendix B to this proxy statement.

• Administration. The plan is administered by the compensation committee of the board, which is composed entirely
of independent directors. The committee has authority to delegate plan administration with respect to employees
other than the executive ofﬁ cers.

• Eligibility. Plan participants include all executive ofﬁ cers, all management employees worldwide, most U.S. and

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Puerto Rico nonmanagement employees, and selected employees outside the United States. The committee may
include other employees at its discretion. For 2004, approximately 20,000 employees are eligible to participate.
• Performance Measures and Bonus Calculation. Prior to the beginning of each year, the committee will establish

the following elements necessary for the bonus calculation:

—Bonus targets are established for participants based on a schedule that associates job responsibilities with a

bonus target amount expressed as a percentage of regular earnings for the year.

—Company performance measures are established for the year. The committee may select one or more from

among the following measures: growth in net income or earnings per share; growth in sales; return on assets;
return on equity; total shareholder return; economic value added (EVA); market value added (MVA); or any of
the foregoing before the effect of acquisitions, divestitures, accounting changes, restructurings, and special
charges (determined according to objective criteria established by the committee not later than 90 days after
the beginning of the year). Unless the committee chooses otherwise, the company performance measure shall
be based 75 percent on earnings-per-share growth and 25 percent on sales growth, in both cases before the
effect of any adjustments as described above. Bonuses for 2004 will be based on this measure.

—A bonus multiple is used to adjust the bonus target to account for company performance. The committee

establishes performance benchmarks for sales and earnings growth after considering expected peer group
performance. If the benchmarks are met exactly, the bonus multiple would be 100 percent of the bonus
target. Actual bonus multiples will vary depending on company performance relative to the benchmarks. The
maximum bonus multiple is 200 percent of the bonus target and the threshhold multiple is 25 percent of the
bonus target, except that the committee has discretion to reduce the bonus multiple to a lower percentage or
to zero. The committee does not have discretion to increase the multiple.

• Individual Performance Adjustments. For employees other than executive ofﬁ cers, the committee may adjust

the award upward by an amount not to exceed 50 percent for exemplary individual performance during the year.
Executive ofﬁ cers’ awards may not be adjusted upward. An employee (including an executive ofﬁ cer) whose
performance is unsatisfactory for the year will not receive a bonus.

• Payment. Payment will be made following certiﬁ cation by the committee of the company’s actual performance

results for the year. No individual bonus payment may exceed $7 million in any one year. Participants must remain
employed until the end of the year to receive a bonus, except in the case of retirement, death, disability, and certain
leaves of absence.

• Amendment. The plan may be amended at any time by the board or the committee. Shareholder approval
of amendments may be sought to the extent the company deems it necessary or advisable to preserve tax-
deductibility under Section 162(m) of the Code.

It is not possible to predict with certainty the bonuses that would be payable to the executive ofﬁ cers with respect
to 2004 performance. However, if the company were to meet the performance benchmarks for earnings-per-share
growth and sales growth, and assuming no change in the regular earnings of the executive ofﬁ cers for the year, the
following bonuses would be paid for 2004 (before taxes):

Mr. Taurel—$1,651,155
Mr. Golden—$609,910
Mr. Mayr—$108,915
Dr. Lechleiter—$670,500
Mr. Granadillo—$523,365
All executive ofﬁ cers as a group (9 ofﬁ cers): $5,210,770.

It is not possible to estimate the aggregate 2004 bonuses that would be payable to all eligible employees as a
group.

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Equity Compensation Plan Information
The following table presents information as of December 31, 2003, about our other compensation plans under
which shares of Lilly stock have been authorized.

Plan category

(a) Number of
securities to be issued
upon exercise of
outstanding options,
warrants, and rights

(b) Weighted-
average exercise
price of outstanding
options, warrants,
and rights

(c) Number of
securities remaining
available for future
issuance under equity
compensation plans
(excluding securities
reﬂ ected in column (a))

Equity compensation plans approved by security holders

70,227,853

Equity compensation plans not approved by security holders (1)

12,582,622

Total

82,810,475

$64.94

$67.93

$65.39

74,455,872

2,121,420

76,577,292

(1) Represents shares in the Lilly GlobalShares Stock Plan, which permits the company to grant stock options to
nonmanagement employees worldwide. The plan is administered by the senior vice president responsible for
human resources. The stock options are nonqualiﬁ ed for U.S. tax purposes. The option price cannot be less than
the fair market value at the time of grant. The options shall not exceed 11 years in duration and shall be subject
to vesting schedules established by the plan administrator. There are provisions for early vesting and early
termination of the options in the event of retirement, disability, and death. In the event of stock splits or other
recapitalizations, the administrator may adjust the number of shares available for grant, the number of shares
subject to outstanding grants, and the exercise price of outstanding grants.

Item 4. Shareholder Proposal Regarding Executive Compensation

The Sheet Metal Workers’ National Pension Fund, Edward F. Carlough Plaza, 601 North Fairfax Street, Suite 500,
Alexandria, Virginia 22314, beneﬁ cial owner of approximately 34,200 shares, has notiﬁ ed the company that it in-
tends to present the following proposal at the annual meeting.

The board recommends that you vote AGAINST this proposal.

Executive Compensation Proposal
Resolved, that the shareholders of Lilly (Eli) & Co. (“Company”) request that the Company’s Board of Directors and
its Executive Compensation Committee replace the current system of compensation for senior executives with the
following “Commonsense Executive Compensation” program including the following features:

(1) Salary—The chief executive ofﬁ cer’s salary should be targeted at the mean of salaries paid at peer group com-

panies, not to exceed $1,000,000 annually. No senior executive should be paid more than the CEO.

(2) Annual Bonus—The annual bonus paid to senior executives should be based on well-deﬁ ned quantitative (ﬁ nan-
cial) and qualitative (non-ﬁ nancial) performance measures. The maximum level of annual bonus should be a
percentage of the executive’s salary level, capped at 100% of salary.

(3) Long-Term Equity Compensation—Long-term equity compensation to senior executives should be in the form
of restricted shares, not stock options. The restricted share program should utilize justiﬁ able performance cri-
teria and challenging performance benchmarks. It should contain a vesting requirement of at least three years.
Executives should be required to hold all shares awarded under the program for the duration of their employ-
ment. The value of the restricted share grant should not exceed $1,000,000 on the date of grant.

(4) Severance—The maximum severance payment to a senior executive should be no more than one year’s salary

and bonus.

(5) Disclosure—Key components of the executive compensation plan should be outlined in the Compensation
Committee’s report to shareholders, with variances from the Commonsense program explained in detail.

The Commonsense compensation program should be implemented in a manner that does not violate any existing
employment agreement or equity compensation plans.

Statement of Support: We believe that compensation paid to senior executives at most companies, including

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ours, is excessive, unjustiﬁ ed, and contrary to the interests of the Company, its shareholders, and other important
corporate constituents. CEO pay has been described as a “wasteland that has not been reformed.” (Institutional
Shareholder Services senior vice-president, Wall Street Journal, “Executive Pay Keeps Rising, Despite Outcry,”
October 3, 2003). As of 2002, the CEO-worker pay gap of 282-to-1 was nearly seven times as large as the 1982 ratio
of 42-to-1 according to the United for a Fair Economy’s Tenth Annual CEO Compensation Survey (“Executive Excess
2003—CEO’s Win, Workers and Taxpayers Lose.”)

We believe that it is long past time for shareholders to be proactive and provide companies clear input on the pa-
rameters of what they consider to be reasonable and fair executive compensation. We believe that executive com-
pensation should be designed to promote the creation of long-term corporate value. The Commonsense executive
compensation principles seek to focus senior executives, not on quarterly performance numbers, but on long-term
corporate value growth, which should beneﬁ t all the important constituents of the Company. We challenge our
Company’s leadership to embrace the ideas embodied in the Commonsense proposal, which still offers executives
the opportunity to build personal long-term wealth but only when they generate long-term corporate value.

Statement in Opposition to the Executive Compensation Proposal
The compensation committee of the board has reviewed the shareholder proposal and ﬁ nds that, on balance, it is
not in the best interests of the shareholders.

The shareholder states that executive compensation should promote the creation of long-term corporate value by
encouraging executives to look beyond quarterly performance numbers and focus on long-term corporate value
growth. We agree. In fact, for many years our executive compensation philosophy has been grounded on the princi-
ple that compensation should foster the long-term focus required for success in the research-based pharmaceuti-
cal industry. For a fuller description of our philosophy, see the compensation committee report on pages 66–68.

Where we differ with the shareholder is in the best way to achieve that objective. The shareholder would have the
board impose a number of strict rules and prohibitions governing nearly all forms of compensation. These stric-
tures would deprive the compensation committee of the ﬂ exibility it needs to respond to changing industry, market,
and compensation trends and to tailor executive compensation programs to attract and retain the highly qualiﬁ ed
individuals necessary to succeed in a competitive world economy.

In particular, we disagree with several of the shareholder’s speciﬁ c prohibitions:
• Salary and bonus caps. The proposal would establish “hard caps” of $1 million on salary and equity grants and
would impose a limit on cash bonuses of 100 percent of salary. This one-size-ﬁ ts-all approach to compensation
would not allow the committee to meet the needs of the marketplace or even adapt for inﬂ ation.

• Elimination of stock options. In the wake of the recent corporate scandals, some commentators have called for
the elimination of stock options, asserting that stock option compensation was a primary cause of the fraud and
governance failures in those cases. We believe that that view overstates the role that stock options played in those
regrettable situations. While excessive reliance on stock option compensation can create unhealthy incentives,
a measured use of stock options as a part of a balanced cash and equity program can provide employees with
healthy, positive incentives to focus on both annual performance goals and long-term growth in shareholder value.
We will continue to monitor this balance over time, particularly in light of possible changes in accounting rules
affecting stock options. However, we do not believe an absolute ban on stock options is appropriate.

In summary, we share the proponent’s goals but not the approach. Effective oversight of executive compensation
is achieved not by imposing a series of inﬂ exible mandates but instead by instituting strong corporate governance
practices to assure that the company’s compensation committee is independent, informed, and active. We believe
that those practices are ﬁ rmly in place at Lilly.

Item 5. Shareholder Proposal Regarding Access and Affordability of Prescription Drugs

Sisters of Mercy, Regional Community of Detroit Charitable Trust, 29000 Eleven Mile Road, Farmington Hills, MI
48336-1405, beneﬁ cial owners of approximately 800 shares, have notiﬁ ed the company that they intend to present
the following proposal at the annual meeting.

The board recommends that you vote AGAINST this proposal.

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Access and Affordability of Prescription Drugs
Resolved, That the Board of Directors review pricing and marketing policies and prepare a report (at reasonable
cost and omitting proprietary information), available to shareholders by September, 2004, on how our company
will respond to rising regulatory, legislative and public pressure to increase access to and affordability of needed
prescription drugs.

Statement of Support: The pharmaceutical industry faces a number of long-term challenges that threaten our
Company’s viability and could adversely affect shareholder value.

“The pharmaceutical industry and its legal representatives are now beset by a torrent of suits alleging fraud and
predatory pricing, demands for more stringent regulation, and investigation of longstanding practices in patenting,
promoting and producing drugs.” (Drug Wars, American Bar Association Journal, December 2002).

The pharmaceutical industry “depends heavily on public trust” and is particularly vulnerable in times of crisis and/or
controversy, according to Rating Research LLC. (Reputation Strength Rating, Rating Research LLC, June 2003).

Only 13% of people “normally believe a statement by a pharmaceutical company.” (Attitudes to Government Regu-
lation Vary Greatly For Different Industries, Harris Interactive, 2 April 2003).

57% of Americans think our industry “should be more regulated by government.” Only 7% responded they pre-
ferred less regulation. (Attitudes to Government Regulation Vary Greatly For Different Industries, Harris Interac-
tive, 2 April 2003).

In an annual survey conducted by the Kaiser Commission on Medicaid and the Uninsured, nearly all states reported
taking action to rein in prescription drug costs in the past year (Rising Costs Prompt States to Reduce Medicaid
Further, NY Times, 23 September 2003).

Given the social and political pressures to resolve the issue of accessibility and affordability of healthcare in the
US, we believe the directors of our company have a duty to inform shareholders of the steps taken to address the
challenges confronting our industry: negative public perceptions, legal actions at state and federal levels on pre-
scription access and anti-trust issues, law suits alleging antitrust and consumer fraud violations.

Statement in Opposition to the Access and Affordability of Prescription Drugs Proposal
The public policy and compliance committee of the board has reviewed the shareholder proposal and is in agree-
ment with the intent of the proposal.
• The board periodically reviews the company’s pricing and marketing policies from the perspective of access to and

affordability of our products.

• Our website currently contains a report on the company’s access-related programs.
• In December 2003, the company published the 2002 Corporate Responsibility Report. This report will be updated
annually and the 2004 report for 2003 will provide additional detailed information regarding our commitment to
access and affordability.

As a result, the committee believes this proposal is not necessary and recommends that you vote against it.

A report detailing the company’s access-related programs has been available on our website since September
2002, and can be reached by selecting Access to Medicines on the www.lilly.com homepage, or from the Products
page. This report includes information about direct patient assistance, patient initiatives, the company’s work with
advocacy organizations, U.S. state and federal initiatives, and international initiatives. Information on how patients
and physicians can access Lilly programs and links to state-sponsored prescription drug assistance programs
throughout the country are included.

Our most recently announced program is LillyAnswers, a program designed to provide needy seniors with access
to Lilly medicines. Patients enrolled in LillyAnswers pay only a $12.00 administrative fee for a 30-day supply of any
Lilly prescription medication at participating pharmacies. Medicare-eligible individuals who do not have public or
private coverage for prescription medicine, and who have an income below 200 percent of the federal poverty level
are eligible for LillyAnswers. Since its inception, LillyAnswers has enrolled more than 239,000 members and ﬁ lled

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approximately 630,000 prescriptions. The program, which began in March 2002, is designed to provide interim, af-
fordable coverage for our products to Medicare recipients until a drug beneﬁ t is available.

In addition, Lilly has a long-standing program called Lilly Cares; its goal is to extend access to our products to all
Americans regardless of their ability to pay. Through Lilly Cares, the company offers free medication, through phy-
sicians, to patients who are otherwise unable to obtain their Lilly medicine. In 2003, Lilly provided more than $216
million in free products to people in need.

Lilly also provides assistance with obtaining reimbursement and product supplies through programs designed
speciﬁ cally for several products, including:
• Gemzar® (cancer)
• Humatrope® (human growth hormone)
• Forteo® (severe osteoporosis)
• Xigris® (severe sepsis)
• Alimta® (malignant pleural mesothelioma)

In each of these programs, the Lilly drug is available at additional savings to our other programs or free. For
example, the Forteo® program offers a 4 week supply (28 days) of Forteo® for a ﬂ at administrative fee of $12.00 to
a broader group than that covered by LillyAnswers, and Gemzar and Alimta are available free of charge to cancer
patients who meet medical and ﬁ nancial eligibility criteria.

The company has a number of other philanthropic efforts under way to increase access to medicines, including
ﬁ nancial support to organizations involved in:
• patient advocacy
• disease and treatment research
• education
• improving access to medical care
• programs that assist patients in getting appropriate treatment and living with their diseases.

In 1999, the company initiated a program to improve access to tuberculosis care worldwide. Working with the
World Health Organization (WHO) and Médecins Sans Frontières (MSF), Lilly now distributes a signiﬁ cant amount
of its production of capreomycin and cycloserine for multi-drug resistant tuberculosis (MDR-TB) via the WHO at a
fraction of production cost. As part of this program, the company will transfer the technology to manufacture these
drugs in nations where the disease is most prevalent and will partner with the WHO, the U.S. Department of Health
and Human Services Center for Disease Control, Brigham and Women’s Hospital (BWH), and Purdue University to
increase both the number of trained personnel and the supply of drugs available to treat MDR-TB.

Finally, the company is dedicated to continuing innovation in the discovery of new drugs for health needs that are
currently unmet. This is our central mission and our ﬁ rst and highest ethical responsibility. By devoting more than
$2 billion each year to pharmaceutical research activities, Lilly bears enormous costs and risks related to discov-
ering and developing new medicines.

The company plans to expand its reporting on these activities in the 2003 Corporate Responsibility Report, which
will be published in 2004. In addition to the actions taken on access to medicines, it will address standards of busi-
ness conduct including political lobbying and contributions and antitrust and competition laws. It will also address
the public relations activities underway to support access to medicines. This report will be made available to
shareholders on the Lilly.com website.

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OTHER MATTERS

Section 16(a) Beneﬁ cial Ownership Reporting Compliance

Under Securities and Exchange Commission rules, our directors and executive ofﬁ cers are required to ﬁ le with the
Securities and Exchange Commission reports of holdings and changes in beneﬁ cial ownership of company stock.
We have reviewed copies of reports provided for the company, as well as other records and information. Based on
that review, we concluded that all reports were timely ﬁ led.

Other Information Regarding the Company’s Proxy Solicitation

We will pay all expenses in connection with our solicitation of proxies. We will pay brokers, nominees, ﬁ ducia-
ries, or other custodians their reasonable expenses for sending proxy material to and obtaining instructions from
persons for whom they hold stock of the company. We expect to solicit proxies primarily by mail, but directors,
ofﬁ cers, and other employees of the company may also solicit in person or by telephone, telefax, or electronic mail.
We have retained Georgeson Shareholder Communications Inc. to assist in the distribution and solicitation of prox-
ies. Georgeson may solicit proxies by personal interview, telephone, telefax, mail, and electronic mail. We expect
that the fee for those services will not exceed $17,000 plus reimbursement of customary out-of-pocket expenses.

By order of the board of directors,

Alecia A. DeCoudreaux
Secretary
March 12, 2004

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APPENDIX A

Audit Committee Charter

Purpose
The audit committee’s primary function is to assist the board of directors in fulﬁ lling its oversight responsibilities
by monitoring:
• The integrity of ﬁ nancial information which will be provided to the shareholders and others;
• The systems of internal controls and disclosure controls which management has established;
• The performance of internal and external audit functions; and
• The company’s compliance with legal and regulatory requirements.

Composition
The committee shall consist of no fewer than three directors. All committee members must meet applicable
New York Stock Exchange (NYSE) and Securities and Exchange Commission (SEC) independence and experience
requirements. All committee members shall be ﬁ nancially literate or must become ﬁ nancially literate within a
reasonable period of time after appointment to the committee. At least one member of the committee shall be an
audit committee ﬁ nancial expert as determined by the board in accordance with NYSE listing standards. At least
one member of the committee shall serve concurrently on the public policy and compliance committee. Committee
members shall not simultaneously serve on the audit committees of more than two other public companies.

The committee members shall be appointed for one-year terms at the annual meeting of the board. The board
shall designate the chairperson.

Administrative Matters
The committee shall meet not less than six times per year and shall report at the next board meeting following
each such committee meeting. The committee shall meet at least annually with the public policy and compliance
committee. This meeting will allow the audit committee to review non-ﬁ nancial legal and regulatory compliance as
well as the risk assessment and risk management processes, which are overseen by the public policy and compli-
ance committee. The committee shall meet periodically with management, the internal auditors, and the indepen-
dent auditor in separate executive sessions. The committee may request an ofﬁ cer or employee of the company,
the company’s outside counsel, or representatives of the company’s independent auditor to attend a meeting of the
committee or to meet with any members of, or advisors to, the committee. The committee may, at any time, retain
its own outside advisors at the company’s expense.

Supporting Corporate Staff
General Auditor
Ofﬁ ce of the Corporate Secretary
Chief Accounting Ofﬁ cer

Duties and Responsibilities
To fulﬁ ll its duties and responsibilities, the Committee shall:

1. Annually review and reassess this charter.

2. Maintain a clear understanding with management and the independent auditors that the committee is directly
responsible for compensation and oversight of the work of the independent auditor, including:
• Having the sole authority (subject to shareholder ratiﬁ cation) to appoint or replace the independent auditor;
• Approving the compensation of the independent auditor;
• Reviewing and evaluating the lead partner of the independent audit team;
• Reviewing the audit scope and audit plan of independent auditor;
• Obtaining and reviewing, at least annually, a report from the independent auditor which describes the ﬁ rm’s

internal compliance procedures, any issues raised from peer reviews, or other quality reviews of the ﬁ rm, any steps
taken to deal with the issues, and all relationships between the ﬁ rm and Lilly;

• Ensuring rotation of the lead audit partner as required by law (or any stricter policies as may be established by the

committee);

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• Setting clear hiring policies for employees or former employees of the independent auditor; and
• Resolving disagreements between management and the independent auditor regarding ﬁ nancial reporting.

3. Pre-approve all audit services and approve permitted non-audit services (including fees and terms) to be per-
formed for Lilly by the independent auditor, consistent with the requirements of the SEC and NYSE or any stricter
standards as may be adopted by the committee.

4. Oversee the internal audit function, including:
• Reviewing the appointment and replacement of the general auditor;
• Reviewing and approving the internal audit plan;
• Reviewing signiﬁ cant reports to management prepared by internal audit (and management’s response); and
• Discussing with the independent auditor and management the responsibilities, budget, and stafﬁ ng of the internal

audit function.

5. Prepare a report for inclusion in the company’s annual proxy statement in accordance with SEC regulations.

6. Review, with management and the independent auditors, the annual and quarterly ﬁ nancial results before they
are ﬁ led in periodic reports with the SEC or other regulators. These reviews shall include discussions with manage-
ment and the independent auditor regarding signiﬁ cant ﬁ nancial reporting issues and judgments made in connec-
tion with the preparation of Lilly’s ﬁ nancial statements and any special steps adopted in light of material control de-
ﬁ ciencies. The committee shall also receive regular reports from the independent auditor on the critical accounting
policies and practices of Lilly and signiﬁ cant alternative treatments of ﬁ nancial information within GAAP that have
been discussed with management. The committee shall discuss with the independent auditor the auditor’s assess-
ment of the quality, not just the acceptability, of the company’s accounting principles as required by SAS No. 61.

7. Review and discuss with management Lilly’s earnings press releases, including the use of “pro forma” non-
GAAP information, as well as ﬁ nancial information and earnings guidance provided to analysts and rating agencies.

8. Provide an open avenue of communication between the independent auditor, the general auditor, and the board,
including sufﬁ cient opportunity for the independent auditor and the general auditor to meet with the committee
without members of management present.

9. Consider and review with the independent auditor, the chief accounting ofﬁ cer, and the general auditor:
• The independent auditors’ audit of ﬁ nancial statements and their report thereof;
• The adequacy of the company’s internal controls and disclosure controls;
• Any related signiﬁ cant ﬁ ndings and recommendations of the independent auditors or the internal auditors together

with management’s responses thereto;

• Any difﬁ culties encountered in the course of the audits, including any restriction on the scope of work or access to

required information; and

• Any material written communications between the independent auditor and management, including management

letters or schedules of unadjusted differences.

10. Oversee the company’s dissemination of and compliance with the company’s code of conduct, including but not
limited to those codes that apply speciﬁ cally to employees involved in matters that affect accounting, auditing, and
ﬁ nancial reporting.

11. Review procedures to promote and protect employee reporting of suspected fraud or wrongdoing relating to ac-
counting, auditing, or ﬁ nancial reporting, including procedures for:
• Receiving, retaining, and addressing complaints received by Lilly relating to such matters;
• Enabling employees to submit to the committee, on a conﬁ dential and anonymous basis, any concerns regarding

such matters; and

• Protecting reporting employees from retaliation.

12. Review policies and procedures with respect to senior management’s expense accounts, including their use of
corporate assets, and consider the results of any review of these areas by the general auditor or the independent
auditor.

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13. Meet at least annually with the public policy and compliance committee to review regulatory and legal compli-
ance matters, including:
• Overall state of compliance
• Signiﬁ cant legal or regulatory compliance exposure
• Material reports or inquiries from regulators.

14. Review with the public policy and compliance committee, at least annually, a summary of the risk assessment
and risk management processes and policies.

15. Inquire of management, the general auditor, and the independent auditors about signiﬁ cant ﬁ nancial risks or
exposures and evaluate the steps management has taken to assess and minimize such risks to the company, in-
cluding review of management’s ﬁ nancial risk management policies.

16. Conduct or authorize investigations into any matters within the committee’s scope of responsibilities. The com-
mittee may retain (at the company’s expense) independent counsel, accountants, or others to assist in the conduct
of any investigation.

17. The committee shall also undertake such additional activities within the scope of its primary functions as the
committee may from time to time determine.

APPENDIX B

Eli Lilly and Company Bonus Plan (effective January 1, 2004)

Section 1. Purpose
The purpose of The Eli Lilly and Company Bonus Plan is to encourage and promote eligible employees to create
and deliver innovative pharmaceutical-based health care solutions that enable people to live longer, healthier and
more active lives, to outgrow our competitors through a constant stream of pharmaceutical innovation, and to ma-
terially increase shareholder value. The Plan is designed to accomplish the following key objectives:
a. motivate superior employee performance through the implementation of a performance-based bonus system

for all eligible management employees, United States employees (including those in Puerto Rico) and other em-
ployees as may be designated from time to time;

b. encourage eligible employees to take greater ownership of the company and provide “Answers that Matter” daily

by creating a direct relationship between key company measurements and individual bonus payouts; and

c. enable the Company to attract and retain employees that will be instrumental in driving sustained growth and
performance of Eli Lilly and Company by providing a competitive bonus program that rewards outstanding per-
formance consistent with the Company’s mission, values and increased shareholder value.

The Plan is intended to satisfy the requirements for providing “performance-based” compensation under Section
162(m) of the Internal Revenue Code.

Section 2. Deﬁ nitions
The following words and phrases as used in this Plan will have the following meanings unless a different meaning
is clearly required by the context. Masculine pronouns will refer both to males and to females:

2.1 Applicable Year means the calendar year immediately preceding the year in which payment of the Company Bo-
nus is payable pursuant to Section 6. For example, the Applicable Year for 2005 payout is January 1, 2004 through
December 31, 2004.

2.2 Bonus Target means the percentage of Participant Earnings for each Participant as described in Section 5.6(a)
below.

2.3 Committee means (i) with respect to the Executive Ofﬁ cers of Lilly, the Compensation Committee, the mem-
bers of which will be selected by the Board of Directors of Lilly, from among its members; and (ii) with respect to
all other Eligible Employees, the Compensation Committee of the Board of Directors or its designee. Each member

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of the Compensation Committee will, to the extent deemed necessary or appropriate by the Board of Directors,
satisfy the requirements of an “outside director” within the meaning of Section 162(m) of the Internal Revenue
Code.

2.4 Company means Eli Lilly and Company and its subsidiaries.

2.5 Company Bonus means the amount of bonus compensation payable to a Participant as described in Section 5
below. Notwithstanding the foregoing, however, the Committee may determine, in its sole discretion, to reduce the
amount of a Participant’s Company Bonus if such Participant becomes eligible to participate in such other bonus
program of the Company as may be speciﬁ cally designated by the Committee. Such reduction may be by a stated
percentage up to and including 100% of the Company Bonus.

2.6 Company Performance Bonus Multiple means the amount as calculated in Sections 5.3 and 5.4 below.

2.7 Disabled means a Participant who (i) has become eligible for a payment under The Lilly Extended Disability
Plan, assuming eligibility to participate in that plan, or (ii) for those employees ineligible to participate in The Lilly
Extended Disability Plan, has become otherwise “disabled” under the applicable disability beneﬁ t plan or program
for the Participant, or, in the event that there is no such disability beneﬁ t plan or program, has become disabled
under applicable local law.

2.8 Earnings Per Share (EPS) means the diluted earnings per share of the Company as reported in the Company’s
“Consolidated Statements of Income” in accordance with generally accepted accounting principles and Section 3.4
below.

2.9 Earnings Per Share Growth (EPS Growth) means the percentage increase in EPS in the Applicable Year com-
pared to the prior year.

2.10 Effective Date means January 1, 2004.

2.11 Eligible Employee means:
a. with respect to employees of Lilly or its Puerto Rican subsidiaries, a person (1) who is employed as an employee
by the Company on a scheduled basis of twenty (20) or more hours per week and is scheduled to work at least
ﬁ ve (5) months per year; and (2) who is receiving compensation, including temporary illness pay under Lilly’s
Illness Pay Program or similar short-term disability program, from the Company for services rendered as an
employee. Notwithstanding anything herein to the contrary, the term “Eligible Employee” will not include:

(1) a person who has reached Retirement with the Company;
(2) a person who is Disabled;
(3) a person who is a “leased employee” within the meaning of Section 414(n) of the Internal Revenue Code
of 1986, as amended, or whose basic compensation for services on behalf of the Company is not paid
directly by the Company;

(4) a person who is classiﬁ ed as a “Fixed Duration Employee”, as that term is used by Lilly;
(5) a person who is classiﬁ ed as a special status employee because his employment status is temporary,

seasonal, or otherwise inconsistent with regular employment status;

(6) a person who is eligible to participate in the Eli Lilly and Company Prem1er Rewards Plan or such other
Company bonus or incentive program as may be speciﬁ cally designated by the Committee or its desig-
nee;

(7) a person who submits to the Committee in writing a request that he not be considered eligible for par-

ticipation in the Plan or is a member of the Board of Directors of Lilly unless he or she is also an Eligible
Employee; or

(8) any other category of employees designated by the Committee in its discretion with respect to any Ap-

plicable Year.

b. with respect to those employees who are employed by the Company, but not by Lilly or a Puerto Rican subsid-

iary, an employee of the Company designated by the Committee as a Participant in the Plan with respect to any
Applicable Year. In its discretion, the Committee may designate Participants either on an individual basis or by
determining that all employees in speciﬁ ed job categories, classiﬁ cations, levels, subsidiaries or other appropri-
ate classiﬁ cation will be Participants.

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c. Notwithstanding anything herein to the contrary, the term Eligible Employee will not include any person who is
not so recorded on the payroll records of the Company, including any such person who is subsequently reclas-
siﬁ ed by a court of law or regulatory body as a common law employee of the Company. Consistent with the
foregoing, and for purposes of clariﬁ cation only, the term employee or Eligible Employee does not include any
individual who performs services for the Company as an independent contractor or under any other non-em-
ployee classiﬁ cation.

2.12 Lilly means Eli Lilly and Company.

2.13 Lilly Executive Ofﬁ cer or Section 162(m) Participant means a Participant who has been designated by the
Board of Directors of Lilly as an executive ofﬁ cer pursuant to Rule 3b-7 under the Securities Exchange Act of 1934,
as amended. For purposes of this Plan, a Lilly Executive Ofﬁ cer will be considered a Section 162(m) Participant
whether or not he is a “covered employee” under Section 162(m).

2.14 Participant means an Eligible Employee who is participating in the Plan.

2.15 Participant Earnings means (A) those amounts described below that are earned during the portion of the Ap-
plicable Year during which the employee is a Participant in the Plan:

(i)

regular compensation (including applicable deferred compensation amounts), overtime, shift pre-
miums and other forms of additional compensation determined by and paid currently pursuant to an
established formula or procedure;

(ii) salary reduction contributions to The Lilly Employee Savings Plan or elective contributions under any

similar tax-qualiﬁ ed plan that is intended to meet the requirements of Section 401(k) of the Internal
Revenue Code or similar Company savings program;

(iii) elective contributions to any cafeteria plan that is intended to meet the requirements of Section 125 of

the Internal Revenue Code or other pre-tax contributions to a similar Company beneﬁ t plan;
(iv) payments made under the terms of Lilly’s Illness Pay Program or other similar Company or govern-
ment-required leave program during an Applicable Year to a Participant who is on approved leave of
absence and is receiving one hundred percent (100%) of his base pay; and

(v) other legally-mandated or otherwise required pre-tax deductions from a Participant’s base salary.

(B) The term “Participant Earnings” does not include:

(i)
(ii)

compensation paid in lieu of earned vacation;
amounts contributed to the Retirement Plan or any other qualiﬁ ed plan, except as provided in clause
(A)(ii), above;

(iii) payments made under the terms of Lilly’s Illness Pay Program or other similar Company or govern-
ment-required leave program during an Applicable Year to a Participant who is on approved leave of
absence and is receiving less than the full amount of his base pay;

(iv) amounts paid under this Plan or other bonus or incentive program of the Company;
(v)
(vi)

payments based upon the discretion of the Company;
in the case of a person employed by a Lilly subsidiary, foreign service, cost of living, or other allowances
that would not be paid were the person employed by Lilly;

(vii) amounts paid as commissions, sales bonuses, or Market Premiums (as deﬁ ned under the Retirement

Plan); or

(viii) earnings with respect to the exercise of stock options or vesting of restricted stock.

2.16 Performance Benchmarks mean the amounts as calculated in Section 5.3 below. The Performance Bench-
marks will be established after considering expected pharmaceutical peer group performance and based on
performance measures as described in Section 5.2.

2.17 Plan means The Eli Lilly and Company Bonus Plan as set forth herein and as hereafter modiﬁ ed or amended
from time to time. The Plan is an incentive compensation program and is not subject to the Employee Retirement
Income Security Act of 1974, as amended (“ERISA”), pursuant to Department of Labor Regulation Section 2510.3.

2.18 Retirement means the cessation of employment upon the attainment of age ﬁ fty-ﬁ ve with ten years of service
(55 and 10) or at least eighty (80) points, as determined by the provisions of the Retirement Plan as amended from
time to time, assuming eligibility to participate in that plan. For persons who are not participants in the Retirement

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Plan, Retirement means the cessation of employment as a retired employee under the applicable retirement ben-
eﬁ t plan or program as provided by the Company or applicable law.

2.19 Retirement Plan means The Lilly Retirement Plan.

2.20 Sales means, for any Applicable Year, the consolidated net sales of the Company as set forth in the “Con-
solidated Statements of Income” as reported by the Company in accordance with generally accepted accounting
principles and Section 3.4 below.

2.21 Sales Growth means the percentage increase in Sales in the Applicable Year compared to the prior year.

2.22 Section 162(m) means Section 162(m) of the Internal Revenue Code of 1986, as amended.

2.23 Service means the aggregate time of employment of an Eligible Employee by the Company.

Section 3. Administration
3.1 Committee. The Plan will be administered by the Compensation Committee of the Board of Directors of Eli Lilly
and Company or, if the name of the Compensation Committee is changed, the Plan will be administered by such
successor committee. For all Eligible Employees other than Lilly Executive Ofﬁ cers, the Compensation Commit-
tee may delegate all or a portion of its responsibilities within its sole discretion by resolution. Any reference in this
Plan to the Committee or its authority will be deemed to include such designees (other than with respect to Lilly
Executive Ofﬁ cers or a member of the Board of Directors or for purposes of Section 9).

3.2 Powers of the Committee. The Committee will have the right to interpret the terms and provisions of the Plan
and to determine any and all questions arising under the Plan, including, without limitation, the right to remedy
possible ambiguities, inconsistencies, or omissions by a general rule or particular decision. The Committee will
have authority to adopt, amend and rescind rules consistent with the Plan, to make exceptions in particular cases
to the rules of eligibility for participation in the Plan (except with respect to Lilly Executive Ofﬁ cers), and to dele-
gate authority for approval of participation of any Eligible Employee except for Lilly Executive Ofﬁ cers or a member
of the Board of Directors. The Committee will take all necessary action to establish annual Performance Bench-
marks and approve the timing of payments, as necessary.

3.3 Certiﬁ cation of Results. Before any amount is paid under the Plan, the Committee will certify in writing the
calculation of EPS, EPS Growth, Sales and Sales Growth (or other applicable performance measures) for the Ap-
plicable Year and the satisfaction of all other material terms of the calculation of the Company Performance Bonus
Multiple and Company Bonus.

3.4 Adjustments for Signiﬁ cant Events. Not later than 90 days after the beginning of an Applicable Year, the Com-
mittee may specify with respect to Company Bonuses for the Applicable Year that the performance measures
described in Section 5.2 will be determined before the effects of acquisitions, divestitures, restructurings or
special charges or gains, changes in corporate capitalization, accounting changes, and/or events that are treated
as extraordinary items for accounting purposes; provided that such adjustments shall be made only to the extent
permitted by Section 162(m) in the case of Lilly Executive Ofﬁ cers.

3.5 Finality of Committee Determinations. Any determination by the Committee of Sales, Sales Growth, EPS, EPS
Growth, any other performance measure, Performance Benchmarks and the level and entitlement to Company
Bonus, and any interpretation, rule, or decision adopted by the Committee under the Plan or in carrying out or
administering the Plan, will be ﬁ nal and binding for all purposes and upon all interested persons, their heirs, and
personal representatives. The Committee may rely conclusively on determinations made by Lilly and its auditors to
determine Sales, Sales Growth, EPS, EPS Growth and related information for administration of the Plan, whether
such information is determined by the Company, auditors or a third-party vendor engaged speciﬁ cally to provide
such information to the Company. This subsection is not intended to limit the Committee’s power, to the extent it
deems proper in its discretion, to take any action permitted under the Plan.

Section 4. Participation In The Plan
4.1 General Rule. Only Eligible Employees may participate in and receive payments under the Plan.

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4.2 Commencement of Participation. An Eligible Employee will become a Participant in the Plan as follows: (i) in
the case of Eligible Employees under Section 2.11(a), on the date on which the individual completes at least one
hour of employment as an Eligible Employee within the United States or Puerto Rico, and (ii) in the case of Eligible
Employees under Section 2.11(b), on the date as of which the Committee has designated the individual to become a
Participant in the Plan.

4.3 Termination of Participation. An Eligible Employee will cease to be a Participant upon termination of employ-
ment with the Company for any reason, or at the time he otherwise ceases to be an Eligible Employee under the Plan.

Section 5. Deﬁ nition And Computation Of Company Bonus
5.1 Computation for Eligible Employees. Company Bonus amounts will depend signiﬁ cantly on Company perfor-
mance as well as Participants’ individual performance for certain Eligible Employees. As more speciﬁ cally de-
scribed below, a Participant’s Company Bonus is calculated by multiplying the Participant’s Bonus Target by his
Participant Earnings and the Company Performance Bonus Multiple. For eligible management and Lilly employees
and those Participants designated by the Committee, individual performance will also impact the Company Bonus
calculation, as described in Section 5.6(c) below. Company Bonuses are paid out to eligible Participants in the
manner provided below.

5.2 Establishment of Performance Measures. Not later than 90 days after the beginning of each Applicable Year, the
Committee will, in its sole discretion, determine appropriate performance measures for use in calculating Com-
pany Bonus amounts. These performance measures may include Sales Growth, EPS Growth, growth in net income,
return on assets, return on equity, total shareholder return, EVA, MVA or any of the foregoing before the effect of
acquisitions, divestitures, accounting changes, restructurings and special charges or gains (determined according
to objective criteria established by the Committee not later than ninety (90) days after the beginning of the Applicable
Year). Unless otherwise speciﬁ ed in a written resolution adopted by the Committee for the Applicable Year, the Com-
mittee will use EPS Growth and Sales Growth, in each case before the effect of acquisitions, divestitures, accounting
changes, restructurings and special charges or gains (determined as described above) as performance measures.

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5.3 Establishment of Performance Benchmarks. Not later than 90 days after the beginning of each Applicable Year,
the Committee will establish Performance Benchmarks for the Company based on the performance measures
described in Section 5.2 above. Unless otherwise speciﬁ ed in a written resolution adopted by the Committee for the
Applicable Year, the Performance Benchmarks will correspond with EPS Growth and Sales Growth amounts for
the Applicable Year, established after considering expected pharmaceutical peer group performance. The Perfor-
mance Benchmarks will correspond to EPS Growth and Sales Growth multiples equal to 1.0. The Committee will
also adopt a formula that will determine the extent to which the performance measure multiples will vary as the
Company’s actual results vary from the Performance Benchmarks.

5.4 Company Performance Bonus Multiple. Unless otherwise speciﬁ ed in a written resolution adopted by the Com-
mittee not later than 90 days after the beginning of the Applicable Year, the Company Performance Bonus Multiple
is equal to the product of the EPS Growth multiple and 0.75 plus the product of the Sales Growth multiple and 0.25
(i.e., Company Performance Bonus Multiple = (EPS Growth multiple * 0.75) + (Sales Growth multiple * 0.25)).

5.5 Company Performance Bonus Multiple Threshold and Ceiling. Notwithstanding Sections 5.3 and 5.4, the
Company Performance Bonus Multiple will not be less than 0.25 or greater than 2.0 in an Applicable Year. If the
calculations described in Sections 5.3 and 5.4 above result in a number that is less than 0.25, the Company Perfor-
mance Bonus Multiple will equal 0.25 for the Applicable Year. If the calculations described in Sections 5.3 and 5.4
above result in a multiple greater than 2.0, the Company Performance Bonus Multiple will equal 2.0 for the Appli-
cable Year. Notwithstanding the foregoing, the Committee may reduce the Company Performance Bonus Multiple
(including but not limited to a reduction to below 0.25) for some or all Eligible Employees, in its discretion.

5.6 Participant Company Bonus.

a. Bonus Target. Not later than 90 days after the beginning of the Applicable Year, the Bonus Target for each

Participant will be determined by the Committee on a basis that takes into consideration a Participant’s pay
grade level and job responsibilities. The Bonus Target for each Participant for the Applicable Year will be
expressed as a percentage of Participant Earnings as of December 31 of the Applicable Year. Early in the Ap-
plicable Year, each Participant will receive information regarding the Participant’s Bonus Target.

b. Company Bonus Calculation. Except as described in Section 5.6(c) below, a Participant’s Company Bonus will
equal the product of the Company Performance Bonus Multiple and the Participant’s Bonus Target and the
Participant’s Earnings.

c. Adjustment for Performance Multiplier, if Applicable. Notwithstanding anything herein to the contrary, all eli-

gible management employees (except Lilly Executive Ofﬁ cers), United States employees and other employees
as may be designated from time to time by the Committee are subject to individual performance multipliers.
For all such Participants subject to an individual performance multiplier, the amount calculated in Section
5.5(b) above will be adjusted based on the Participant’s performance rating at the end of the Applicable Year
as described below. For each such Participant, the performance rating will be determined by the Partici-
pant’s supervision.

1. Exemplary Performance. If the Participant receives an exemplary or equivalent performance rating (us-
ing the applicable performance rating system then in effect for the Participant), the amount calculated
in Section 5.6(b) will be multiplied by an amount determined by the Committee, not to exceed 1.5, to
obtain the Participant’s actual Company Bonus.

2. Satisfactory Performance. If the Participant receives a satisfactory or equivalent performance rating
(using the applicable performance rating system then in effect for the Participant), the amount calcu-
lated in Section 5.6(b) will be multiplied by 1.0 so that the Participant’s actual Company Bonus will equal
the amount calculated in Section 5.6(b) above.

3. Unsatisfactory Performance. If the Participant receives a year-end unsatisfactory or equivalent perfor-
mance rating (using the applicable performance rating system then in effect for the Participant), the
amount calculated in Section 5.6(b) will be multiplied by 0.0 so that the Participant’s actual Company
Bonus will equal $0.00.

In the event that a Participant does not receive a year-end performance rating, but is eligible for a Company Bonus,
the amount calculated in Section 5.6(b) will be multiplied by 1.0 so that the Participant’s actual Company Bonus will
be the amount calculated in Section 5.6(b) above.

5.7 Conditions on Company Bonus. Payment of any Company Bonus is neither guaranteed nor automatic. A Partici-
pant’s Company Bonus is not considered to be any form of compensation, wages, or beneﬁ ts, unless and until paid.

5.8 Required Employment. Except as provided below in this Section 5.8 or as otherwise designated by the Commit-
tee, if a Participant is not employed by the Company on the last day of the Applicable Year, or is otherwise not an
Eligible Employee on that date, the Participant is not entitled to any Company Bonus payment under this Plan for
that Applicable Year.

a. Leaves of Absence. A Participant who, on the last day of the Applicable Year, is on approved leave of absence
under the Family and Medical Leave Act of 1993, military leave under the Uniformed Services Employment
and Reemployment Rights Act, or such other approved leave of absence will be considered to be an Eligible
Employee on that date for purposes of this Plan.

b. Transfer. An employee who is a Participant in this Plan for a portion of the Applicable Year and then trans-
fers to a position within the Company in which he is ineligible to participate in this Plan, but who remains
employed by the Company on the last day of the Applicable Year, will be treated as satisfying the last-day-
of-Applicable Year requirement for purposes of this Plan. In that event, his Company Bonus will be based on
his Participant Earnings for the portion of the Applicable Year in which the employee was a Participant in the
Plan.

c. Retirement, Disability or Death. A Participant who was an Eligible Employee for some portion of the Appli-

cable Year and then takes Retirement, becomes and remains Disabled through the end of the Applicable Year,
or dies during the Applicable Year will be considered to satisfy the last-day-of-Applicable-Year requirement
described in this Section 5.8 for purposes of this Plan.

d. Notice of Resignation. In addition, a Participant who submits a notice of resignation from employment with the
Company prior to the end of the Applicable Year and whose effective date of resignation is two (2) weeks or
less from the date of notice of resignation will be considered employed by the Company for purposes of this
Plan until the end of his speciﬁ ed notice period.

5.9 New Participants. If an Eligible Employee began participation in the Plan during an Applicable Year and is
eligible for a Company Bonus, his Company Bonus will be based on Participant Earnings earned after the employee
became a Participant. An Eligible Employee who became assigned to a position eligible for a Company Bonus at

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any time other than the ﬁ rst of the month will become a Participant the ﬁ rst of the following month.

5.10 Section 162(m) Requirements, Bonus Maximum. In the case of Lilly Executive Ofﬁ cers, all determinations
necessary for computing a Company Bonus for the Applicable Year, including establishment of all components of
EPS, EPS Growth, Sales, Sales Growth, Company Performance Bonus Multiple and Bonus Target percentages,
shall be made by the Committee not later than 90 days after the commencement of the Applicable Year. As and to
the extent required by Section 162(m), the terms of a Company Bonus for a Lilly Executive Ofﬁ cer must state, in
terms of an objective formula or standard, the method of computing the amount of compensation payable to the
Lilly Executive Ofﬁ cer, and must preclude discretion to increase the amount of compensation payable that would
otherwise be due under the terms of the award. Notwithstanding anything elsewhere in the Plan to the contrary,
the maximum amount of the Company Bonus that may be payable to a Lilly Executive Ofﬁ cer in respect of any Ap-
plicable Year will be $7 million.

Section 6. Time Of Payment
6.1 General Rule. Payment under the Plan will be made prior to April 1 of the year following the Applicable Year.

6.2 Terminated Employee. Except as provided in Section 5.8 above, in the event an Eligible Employee’s employment
with the Company ends for any reason prior to the last day of the Applicable Year, he will not receive any Company
Bonus for the Applicable Year.

6.3 Deceased Eligible Employee. In the event an Eligible Employee dies before payment under the Plan is made, the
Committee may, in its sole discretion, authorize the Company to pay to his personal representative or beneﬁ ciary an
amount not to exceed the amount established by the Committee to reﬂ ect the payment accrued at the date of death.

Section 7. Administrative Guidelines
7.1 Establishment and Amendment by the Committee. The Committee may establish objective and nondiscrimina-
tory written guidelines for administering those provisions of the Plan that expressly provide for the determination
of eligibility, Company Bonus or beneﬁ ts on the basis of rules established by the Committee. The Committee may,
from time to time, amend or supplement the administrative guidelines established in accordance with this subsec-
tion 7.1. The administrative guidelines established or amended in accordance with this subsection 7.1 will not be ef-
fective to the extent that they materially increase the Plan’s liability, or to the extent that they are inconsistent with,
or purport to amend, any provision of the Plan set forth in a document other than such administrative guidelines.

7.2. Amendment by Board of Directors. Any administrative guidelines established by the Committee pursuant to
subsection 7.1 may be amended or revoked by the Board of Directors, either prospectively or retroactively, in ac-
cordance with the general amendment procedures set forth in section 9 below.

Section 8. Miscellaneous
8.1 No Vested Right. No employee, participant, beneﬁ ciary, or other individual will have a vested right to a Company
Bonus or any part thereof until payment is made to him under Section 6.

8.2 No Employment Rights. No provision of the Plan or any action taken by the Company, the Board of Directors
of the Company, or the Committee will give any person any right to be retained in the employ of the Company. The
right and power of the Company to dismiss or discharge any Participant for any reason or no reason, with or with-
out notice, is speciﬁ cally reserved.

8.3 No Adjustments. After the certiﬁ cation of the calculation of EPS, EPS Growth, Sales, Sales Growth and any
other material terms of the calculation of the Company Performance Bonus Multiple and Company Bonus for the
Applicable Year as described in Section 3.3 above, no adjustments will be made to reﬂ ect any subsequent change in
accounting, the effect of federal, state, or municipal taxes later assessed or determined, or otherwise.

8.4 Other Representations. Nothing contained in this Plan, and no action taken pursuant to its provisions, will cre-
ate or be construed to create a trust of any kind, or a ﬁ duciary relationship between the Company and any em-
ployee, participant, beneﬁ ciary, legal representative, or any other person. Although Participants generally have no
right to any payment from this Plan, to the extent that any Participant acquires a right to receive payments from the
Company under the Plan, such right will be no greater than the right of an unsecured general creditor of the Com-

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pany. All payments to be made hereunder will be paid from the general funds of the Company and no special or
separate fund will be established, and no segregation of assets will be made, to assure payment of such amount.

8.5 Tax Withholding. The Company will make such provisions and take such steps as it may deem necessary or ap-
propriate for the withholding of all federal, state, local, and other taxes required by law to be withheld with respect
to Company Bonus payments under the Plan, including, but not limited to, deducting the amount required to be
withheld from the amount of cash otherwise payable under the Plan, or from salary or any other amount then or
thereafter payable to an employee, Participant, beneﬁ ciary, or legal representative.

8.6 Currency. The Company Bonus will be based on the currency in which the highest portion of base pay is regu-
larly paid. The Committee will determine the appropriate foreign exchange conversion methodology in its discretion.

8.7 Effect of Plan on other Company plans. Nothing contained in this Plan is intended to amend, modify, terminate,
or rescind other beneﬁ t or compensation plans established or maintained by the Company. Whether and to what
extent a Participant’s Company Bonus is taken into account under any other plan will be determined solely in ac-
cordance with the terms of such plan.

8.8 Construction. This Plan and all the rights thereunder will be governed by, and construed in accordance with,
the laws of the State of Indiana, without reference to the principles of conﬂ icts of law thereof.

8.9 Notice. Any notice to be given to the Company or Committee pursuant to the provisions of the Plan will be in
writing and directed to Secretary, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285.

Section 9. Amendment, Suspension, Or Termination
The Board of Directors of the Company will have the right to amend, modify, suspend, revoke, or terminate the
Plan, in whole or in part, at any time and without notice, by written resolution of the Board of Directors. The Com-
mittee also will have the right to amend the Plan, except that the Committee may not amend this Section 9. Solely
to the extent deemed necessary or advisable by the Board (or the Committee) for purposes of complying with
Section 162(m), the Board (or the Committee) may seek the approval by the Company’s stockholders of the Plan or
any amendments to the Plan or any aspect of the Plan or Plan amendments. Any such approval shall be obtained in
a separate vote of stockholders, with approval by a majority of the votes cast on the issue, including abstentions to
the extent abstentions are counted as voting under applicable state law and the Articles of Incorporation and By-
laws of the Company. To the extent deemed necessary or advisable by the Board of Directors to comply with Sec-
tion 162(m), the material terms of the performance measures used in calculating Company Bonus amounts will be
disclosed to and reapproved by the stockholders of the Company no later than the Company’s 2009 annual meeting.

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SENIOR MANAGEMENT

Sidney Taurel A,B

Chairman of the Board, President, and Chief Executive Ofﬁ cer

Robert A. Armitage A,B

Senior Vice President and General Counsel

Charles E. Golden A,B

Executive Vice President and Chief Financial Ofﬁ cer

Pedro P. Granadillo A,B

Senior Vice President

John C. Lechleiter, Ph.D. A,B

Executive Vice President, Pharmaceutical Operations

Steven M. Paul, M.D. A,B

Executive Vice President, Science and Technology

Gino Santini A,B

President, U.S. Operations

Lorenzo Tallarigo, M.D. A,B

President, International Operations

Alpheus Bingham, Ph.D. B

Vice President, e.Lilly

Alan Breier, M.D. B

Vice President, Medical, and Chief Medical Ofﬁ cer

Scott A. Canute B

Vice President, Manufacturing

Bryce D. Carmine B

President, Primary Care Products

Frank M. Deane, Ph.D. B

Vice President, Quality

W. Roy Dunbar B

President, Intercontinental Operations

Timothy R. Franson, M.D. B

Vice President, Global Regulatory Affairs

James A. Harper B

Group Vice President, Global Marketing and Sales, and Chief Marketing Ofﬁ cer

Michael C. Heim B

Vice President and Chief Information Ofﬁ cer

Patrick C. James B

President, Elanco Animal Health

Elizabeth H. Klimes B

President, Specialty Care Products

Anne Nobles B

Vice President, Corporate Affairs

Richard D. Pilnik B

President, European Operations

Lori V. Queisser B

Vice President and Chief Compliance Ofﬁ cer

David E. Thompson B

Vice President, Corporate Strategy and Business Development

Albertus J. van den Bergh B

President, Neuroscience Products

Thomas R. Verhoeven, Ph.D. B

Vice President, Product Research Development

Alfonso G. Zulueta B

Vice President, Sales and Marketing—Primary Care/Neuroscience

A Policy Committee
B Senior Management Forum

Establishes corporate strategy and policy and ensures compliance
Implements corporate strategies and ensures corporate performance, identiﬁ es issues and opportunities,
and facilitates communication and learning

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CORPORATE INFORMATION

Annual meeting
The annual meeting of shareholders will be held at Lilly
Center, Eli Lilly and Company, Indianapolis, Indiana, on
Monday, April 19, 2004, 11:00 a.m. EST (Indianapolis
time). For more information, see the proxy statement
section of this report.

10-K and 10-Q reports
Paper copies of the company’s Annual Report to the
Securities and Exchange Commission on Form 10-K will
be available in April. Quarterly reports on Form 10-Q are
also available upon request. Anyone wishing to receive
copies of the company’s 10-K or 10-Q reports may send a
written request to:

Eli Lilly and Company
P.O. Box 88665
Indianapolis, Indiana 46208-0665

To access these reports more quickly, you can ﬁ nd all our
SEC ﬁ lings online at: http://investor.lilly.com/edgar.cfm

Stock listings
Eli Lilly and Company common stock is listed on the U.S.
New York and Paciﬁ c stock exchanges and the London and
Swiss stock exchanges. NYSE ticker symbol: LLY. Most
newspapers list the stock as “Lilly (Eli) and Co.”

Transfer agent and registrar
Wells Fargo Shareowner Services
Mailing address: Shareowner Relations Department
P.O. Box 64854
St. Paul, Minnesota 55164-0854

Overnight address: 161 North Concord Exchange

South St. Paul, Minnesota 55075

Telephone: 1-800-833-8699
E-mail: stocktransfer@wellsfargo.com
Internet: http://www.wellsfargo.com/com/
shareowner_services

Dividend reinvestment and stock purchase plan
Wells Fargo Shareowner Services administers the Share-
owner Service Plus Plan, which allows registered share-
holders to purchase additional shares of Lilly common
stock through the automatic investment of dividends.
The plan also allows registered shareholders and new
investors to purchase shares with cash payments, either
by check or by automatic deductions from checking or
savings accounts. The minimum initial investment for
new investors is $1,000. Subsequent investments must be
at least $50. The maximum cash investment during any
calendar year is $150,000. Please direct inquiries concern-
ing the Shareowner Service Plus Plan to:

Wells Fargo Shareowner Services
Shareowner Relations Department
P.O. Box 64854
St. Paul, Minnesota 55164-0854
Telephone: 1-800-833-8699

Online delivery of proxy materials
Shareholders may now elect to receive annual reports and
proxy materials online. This reduces paper mailed to the
shareholder’s home and saves the company printing and
mailing costs. To enroll, go to http://proxyonline.lilly.com
and follow the directions provided.

Policy on the issue of access to medicines
Lilly’s policy on the issue of patient access to medicines
is available online: www.lilly.com/about/overview/access/
access.html

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TRADEMARKS

Afﬁ nitak™
Actos®
Alimta®
Axid®
Ceclor®
Cialis®
Coban®
Cymbalta™
Evitsa®
Forteo®
Gemzar®
Humalog®
Humatrope®
Humulin®
Permax®
Prozac®
Prozac® Weekly™
ReoPro®
Rumensin®
Sarafem®
Strattera®
Symbyax™
Tylan®
Vancocin®
Xigris®
Zyprexa®

(LY900003 and formerly ISIS 3521, ISIS Pharmaceuticals), Lilly
(pioglitazone hydrochloride, Takeda), Takeda Chemical Industries, Ltd.
(pemetrexed disodium, Lilly)
(nizatidine, Lilly), Reliant Pharmaceuticals, LLC
(cefaclor, Lilly)
(tadalaﬁ l, ICOS), Lilly ICOS LLC
(monensin sodium, Elanco)
(duloxetine hydrochloride, Lilly)
(raloxifene hydrochloride, Lilly)
(teriparatide of recombinant DNA origin, Lilly)
(gemcitabine hydrochloride, Lilly)
(insulin lispro of recombinant DNA origin, Lilly)
(somatropin of recombinant DNA origin, Lilly)
(human insulin of recombinant DNA origin, Lilly)
(pergolide mesylate, Lilly)
(ﬂ uoxetine hydrochloride, Dista)
(ﬂ uoxetine hydrochloride, Lilly)
(abciximab, Centocor), Lilly
(monensin sodium, Elanco)
(ﬂ uoxetine hydrochloride, Lilly), Galen (Chemicals) Limited
(atomoxetine hydrochloride, Lilly)
(olanzapine/ﬂ uoxetine hydrochloride, Lilly)
(tylosin, Elanco)
(vancomycin hydrochloride, Lilly)
(drotrecogin alfa (activated), Lilly)
(olanzapine, Lilly)

Actos® is a trademark of Takeda Chemical Industries, Ltd.
Axid® is a trademark of Reliant Pharmaceuticals, LLC.
Cialis® is a trademark of Lilly ICOS LLC.
EVA® is a trademark of Stern Stewart & Co.
Sarafem® is a trademark of Galen (Chemicals) Limited.

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ANNUAL MEETING ADMISSION TICKET

Eli Lilly and Company 2004 Annual Meeting of Shareholders
Monday, April 19, 2004
11 a.m. EST (Indianapolis time)

Lilly Center Auditorium
Lilly Corporate Center
Indianapolis, Indiana 46285

The top portion of this page will be required to admit you to the meeting.
Please write your name and address in the space provided below and present this ticket when you enter the Lilly
Center.

A reception (beverages only) will be held from 9:30 to 10:45 a.m. in the Lilly Center.

Name

Address

City, State, and Zip Code

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Detach here

Directions and Parking

From I-70 take Exit 79B; follow signs to McCarty Street. Turn right (east) on McCarty Street; go straight into
Lilly Corporate Center. You will be directed to parking. Be sure to take the admission ticket (the top portion of this
page) with you to the meeting and leave this parking pass on your dashboard.

Take the top portion of this page with you to the meeting.

Detach here

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Eli Lilly and Company
Annual Meeting of Shareholders
April 19, 2004

Complimentary Parking
Lilly Corporate Center

Please place this identiﬁ er on the dashboard of your car as you enter Lilly Corporate
Center so it can be clearly seen by security and parking personnel.

435804

Eli Lilly and Company
Lilly Corporate Center
Indianapolis, Indiana 46285 USA