Eli Lilly and Company
2007 Annual Report
Notice of 2008
Annual Meeting
Proxy Statement
Eli Lilly and Company
Lilly Corporate Center
Indianapolis, Indiana 46285 USA
www.lilly.com
On the Cover
Candy Edwards is a wife, mother, grandmother and self-taught artist
with a passion for helping others. She also is a Cymbalta® patient.
Just two years ago, Candy developed a staph infection that kept her
hospitalized and bedridden for several months. The infection was so
severe that it nearly killed her. Although Candy survived, she found
herself in a world of intense pain, fear, anger and despair. The spirited
woman her family, friends and community knew so well soon became
someone they hardly recognized. Candy lost interest in everything she
cared about—even her family and her art.
“I cried all the time and I had terrible mood swings,” said Candy. “I felt
like I was in this deep hole—it was like I was pinned down. Suicide
seemed to be the only way out.”
Fortunately, Candy’s husband of 30 years, Freddie, recognized that
something was seriously wrong with the woman he loved, and he
pleaded with her to talk to her doctor. Although she was reluctant
at fi rst to accept her diagnosis of depression and initially refused to
take the medicine her doctor gave her, Candy eventually decided to
give it a try.
Candy’s doctor had prescribed Cymbalta, and she recalls that within a
week, she could tell a difference.
“Cymbalta works for me,” she said. The turning point was the day she
woke up and decided to put on her make-up—something she hadn’t
done for nearly 6 months. “I fi nally started to feel like I was back.”
Today, Candy is using her love of art to help raise awareness about
highway safety in her home state of Georgia. She has created
characters such as “Boostie,” who promotes the importance of booster
seats for young children, and “Buckley,” a character who encourages
motorists to wear seatbelts.
Candy isn’t shy about telling her story to others, and by doing so she
has become a source of hope and inspiration for others suffering from
depression in her community.
“I always tell them to talk to their physician,” Candy said. “If I hadn’t
sought help, I might have lost everything. I have my family and my life
back. It was a blessing.”
Year in Review
1 Financial Highlights
2 Letter to Shareholders
6
Innovation at Lilly: The Portfolio and the Pipeline
9 Beyond Medicine: Providing Answers That Matter
Financials
10 Review of Operations
14 Consolidated Statements of Income
19 Consolidated Balance Sheets
20 Consolidated Statements of Cash Flows
21 Consolidated Statements of Comprehensive Income
30 Segment Information
31 Selected Quarterly Data
32 Selected Financial Data
33 Notes to Consolidated Financial Statements
57 Management’s Reports
58 Report of Independent Registered Public Accounting Firm
Proxy Statement
60 Notice of 2008 Annual Meeting and Proxy Statement
61 General Information
65 Board of Directors
69 Highlights of the Company’s Corporate Governance Guidelines
77 Directors and Corporate Governance Committee Matters
78 Audit Committee Matters
80 Compensation Committee Matters
81 Executive Compensation
101 Ownership of Company Stock
102
115 Other Matters
Items of Business To Be Acted Upon at the Meeting
Corporate Information
124 Senior Management and Board of Directors
126 Corporate Information
127 Annual Meeting Admission Ticket
Trademarks
Actos®
Alimta®
Arxxant®
Axid®
Byetta®
Ceclor®
Cialis®
Coban®
Cymbalta®
Effi ent™
Evista®
Forteo®
Gemzar®
Humalog®
Humatrope®
Humulin®
Permax®
Prozac®
ReoPro®
Rumensin®
Strattera®
Surmax®
Symbyax®
Tylan®
Vancocin®
Xigris®
Yentreve®
Zyprexa®
(pioglitazone hydrochloride)
(pemetrexed disodium)
(ruboxistaurin mesylate)
(nizatidine)
(exenatide injection)
(cefaclor)
(tadalafi l)
(monensin sodium), Elanco
(duloxetine hydrochloride)
(prasugrel)
(raloxifene hydrochloride)
(teriparatide of recombinant DNA origin)
(gemcitabine hydrochloride)
(insulin lispro of recombinant DNA origin)
(somatropin of recombinant DNA origin)
(human insulin of recombinant DNA origin)
(pergolide mesylate)
(fl uoxetine hydrochloride)
(abciximab), Centocor
(monensin sodium), Elanco
(atomoxetine hydrochloride)
(avilamycin), Elanco
(tylosin), Elanco
(vancomycin hydrochloride)
(drotrecogin alfa [activated])
(duloxetine hydrochloride)
(olanzapine)
(olanzapine/fl uoxetine hydrochloride)
Prozac® Weekly™
(fl uoxetine hydrochloride)
Zyprexa® Zydis®
(olanzapine)
Actos® is a trademark of Takeda Chemical Industries, Ltd.
AIR® is trademark of Alkermes, Inc.
Axid® is a trademark of Reliant Pharmaceuticals, LLC.
Byetta® is a trademark of Amylin Pharmaceuticals, Inc.
Cialis® is a trademark of Lilly ICOS LLC.
EVA® is a trademark of Stern Stewart & Co.
Sarafem® is a trademark of Galen (Chemicals) Limited
Vancocin® is a trademark of ViroPharma Incorporated
Zydis® is a trademark of Cardinal Health.
All trademarks listed above are trademarks of Eli Lilly and Company unless otherwise noted.
For More Information
Lilly corporate responsibility and report of political fi nancial support . . www.lilly.com/about/citizenship/index.html
Lilly clinical trials registry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . www.lillytrials.com
Lilly Grant Offi ce . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . www.lillygrantoffi ce.com
Multi-drug resistant tuberculosis initiative . . . . . . . . . . . . . . . . . . . . . . . . . www.lillymdr-tb.com
Medicare prescription drug coverage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . www.lillymedicareanswers.com
Pharmaceutical industry patient assistance programs . . . . . . . . . . . . . . . www.pparx.org
Lilly Cares. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . www.lillycares.com or call toll-free 1-800-545-6962
© 2008 Eli Lilly and Company
2007AR
2007 Financial Highlights
ELI LILLY AND COMPANY AND SUBSIDIARIES
(Dollars in millions, except per-share data)
Year Ended December 31
2007
2006
Change %
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net sales—pro forma1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$18,633.5
18,706.2
$15,691.0
16,446.2
Research and development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
3,486.7
3,129.3
Research and development as a percent of net sales . . . . . . . . . . . . .
18.7%
19.9%
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 2,953.0
$ 2,662.7
Earnings per share—diluted. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Reconciling items2:
Acquired in-process research and development . . . . . . . . . . . . . .
Asset impairments, restructuring, and other special charges . . .
Reduction in expected insurance recoveries for
product liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Pro forma adjustment as if the ICOS acquisition was
completed on January 1, 20061 . . . . . . . . . . . . . . . . . . . . . . . . . .
Adjusted earnings per share—diluted. . . . . . . . . . . . . . . . . . . . . . . . . .
Dividends paid per share. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2.71
2.45
.63
.15
.06
(.01)
3.54
1.70
—
.73
—
(.15)
3.03
1.60
Capital expenditures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1,082.4
1,077.8
Employees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
40,600
41,500
19
14
11
11
17
6
—
(2)
1Pro forma sales and earnings per share assume that the ICOS acquisition was completed January 1, 2006. The pro
forma results are presented in order to provide additional insights into the underlying trends in the business.
2For more information on these reconciling items, see the Financial Results section of the Executive Overview on
page 10.
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To Our Shareholders
Eli Lilly and Company delivered outstanding results in
2007, highlighted by 14 percent pro forma sales growth,
17 percent growth in pro forma adjusted net income, and
the movement of no fewer than 16 new molecules into
clinical testing. Measured more broadly by the growth
of our recently launched products in diverse markets,
the success of our business development efforts, and the
progress of discoveries through our development pipe-
line, 2007 was one of the most thoroughly successful
years in Lilly’s history.
Just as importantly in 2007, we asserted a new vision
of the company—dedicated to improving outcomes for in-
dividual patients—and we accelerated the transformation
of Lilly to realize this aspiration.
In this letter, we look forward to reporting on all of
these accomplishments in more detail.
increased 14 percent, to $18.706 billion. Our sales growth
outpaced the overall pharmaceutical sector in each of the
world’s largest markets—the U.S., Europe, and Japan—
and we achieved a 7 percent increase in sales volume
worldwide on a pro forma basis.
Demonstrating our continued commitment to grow
sales faster than operating expenses, pro forma adjusted
net income and earnings per share (EPS) both grew by
17 percent in 2007, to $3.863 billion and $3.54, respec-
tively. On a reported basis, the growth was 11 percent, to
$2.953 billion and $2.71. The pro forma adjusted results
assume we owned ICOS for both years and also adjust for
product liability expenses, asset impairments, and restruc-
turing in both years as well as for charges related to the
acquisition of compounds in development in 2007 (for a
reconciliation, see page 1).
Leadership Transition
Product Performance
Near the end of 2007, we announced a leadership
transition between us that had been carefully planned
for some time. Sidney Taurel will retire as chief executive
offi cer at the end of March 2008, turning over that role to
John Lechleiter. Taurel will remain chairman of the board
until the end of 2008.
Lechleiter assumes his new role as well prepared as any
of his nine predecessors at the helm of Eli Lilly and Com-
pany. A Ph.D. chemist who joined Lilly in 1979 in process
research and development (R&D), Lechleiter will redouble
Lilly’s commitment to develop fi rst-in-class and best-in-class
products. He also brings extensive experience in product
development, regulatory affairs, and global operations.
Already, he has held the reins as operational leader of Lilly
for more than two years, a period of solid sales growth and
steady performance in R&D, manufacturing, and marketing.
Our partnership in leading Lilly during the past two
years has been close and fruitful, and the nature of our
transition demonstrates a broader unity of purpose inside
the company. Lilly’s vision of delivering optimal outcomes
for individual patients is not “Sidney’s” or “John’s.” It is a
vision that we share and one that embodies the promise
of new science, the realities of the external environment,
and the aspirations of our Lilly colleagues worldwide.
We also share a belief that the Lilly CEO’s most im-
portant role is to continuously strengthen the company’s
founding values of excellence, integrity, and respect for
people. In view of the expectations and scrutiny directed at
our industry today, it has never been more important for ev-
eryone at Lilly to live up to these standards, demonstrating
their best performance as well as conduct beyond reproach.
Financial Results
In 2007, Lilly sales increased 19 percent on a reported
basis, to $18.634 billion. On a pro forma basis, which as-
sumes we owned ICOS in both 2006 and 2007, our sales
2
Lilly’s top-selling product, Zyprexa, is beginning
to face competition from generic formulations in some
countries—notably Canada and Germany—but overall
demand for this neuroscience therapy grew in markets
outside the United States during 2007, helping to drive
worldwide sales up 9 percent to $4.761 billion. In the
U.S., a longstanding downward trend in Zyprexa’s share
of new retail prescriptions continued to slow in 2007,
in spite of new competitive products, label changes, and
negative advertising by trial lawyers.
Wider loss of patent protection on Zyprexa and other
products early in the next decade heightens the impor-
tance of strong sales growth among our newer products—
and they have risen to the challenge. Pro forma sales of
Lilly products launched in this decade collectively grew
by 33 percent in 2007 and represented 32 percent of our
total sales, up from 28 percent in 2006.
Cymbalta remains of particular importance to Lilly’s
overall performance in the years ahead, and we are
pleased that its success in 2007 is essentially unquali-
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John C. Lechleiter, Ph.D.
Sidney Taurel
President and
Chief Operating Offi cer
Chairman of the Board and
Chief Executive Offi cer
fi ed. Worldwide sales of Cymbalta grew by 60 percent
in 2007, pushing it above the $2 billion mark in annual
sales for the fi rst time. We believe that the quality of our
sales force interactions, our investment in advertising
directly to consumers, and the product’s strong access to
formularies all play a role in its success—but no factor
is more important than Cymbalta’s ability to address
important medical needs. The patient on the cover of this
annual report is one of the many people whose health has
improved with the help of Cymbalta.
Cymbalta also benefi ted in 2007 from the approval of
new indications. The U.S. Food and Drug Administration
(FDA) approved Cymbalta for generalized anxiety disorder
and for maintenance treatment of major depressive disor-
der (MDD) in adults. In 2007, we also submitted Cymbalta
for consideration as a treatment for fi bromyalgia.
Lilly’s cancer-fi ghting therapy Alimta was another
very strong performer in 2007, growing by 40 percent
worldwide to $854 million. Alimta is now approved in 86
countries; it is the worldwide market leader in second-line
treatment of non-small cell lung cancer, and we are pursu-
ing additional indications for other tumor types.
Our osteoporosis treatment Forteo, sold as Forsteo
in some countries, had a good year as well, growing 19
percent in its fi fth year on the market. Demonstrating our
commitment to individual patient outcomes, we devel-
oped programs to improve adherence to treatment with
Forteo—a major factor in determining its success—and
saw signifi cant improvements in the percentage of pa-
tients who continued to use the product for the optimal
18 to 24 months.
Byetta, the diabetes product Lilly co-developed with
Amylin, achieved sales growth of 51 percent in 2007,
mainly in the U.S. Sales outside the U.S. will begin to
contribute on a larger scale, as we launched Byetta in
22 countries during 2007 and plan to launch in up to 45
more in 2008. We are pleased with Byetta’s track record
of market access and reimbursement—based on its favor-
able evaluation as a true breakthrough in the treatment
of type 2 diabetes. Clinical research shows that Byetta
is helping many patients achieve better glucose control
while losing weight.
In our letter to you last year, we said that reacceler-
ating Lilly’s larger diabetes business—based heavily on
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the Humalog insulin family—was a key goal. Lilly made
progress against that goal in 2007, though we are not yet
satisfied. Humalog is gaining share again in some mar-
kets, driving 20 percent growth outside the U.S. for 2007
as a whole and 32 percent in the fourth quarter. In the
U.S., our total Humalog prescription volume grew in 2007
for the first time in four years, and we aim to sustain that
trend along with gaining new-prescription market share.
Our summary of Lilly’s progress in 2007 would not
be complete without attention to the remarkable contribu-
tions of our Elanco Animal Health business unit. Elanco’s
worldwide sales reached nearly $1 billion in 2007, an in-
crease of 14 percent. The acquisition in 2007 of Ivy Animal
Health and the ongoing launches of products for compan-
ion animals—six are planned within four years—position
Elanco for continued significant growth in the years ahead.
Pipeline Progress
The long-term health of any pharmaceutical company
is determined by its R&D pipeline—the promise of future
breakthroughs. By that measure, we believe that the
outlook for Lilly is robust. In 2007, Lilly brought 16 new
molecular entities (NMEs) into human trials—a record
unparalleled in our history. We increased our portfolio
of new molecules being tested on patients by nearly 50
percent, to 44, and in 2008 we are poised to add another
15 clinical candidates.
A highlight of our late-stage development in 2007
was the submission of prasugrel to the FDA for approval
at year’s end, after an all-out effort by Lilly’s medical and
regulatory affairs teams. Prasugrel (the proposed trade-
mark is Effient™) is a potential new treatment for patients
with acute coronary syndrome (ACS) who are undergoing
angioplasty.
In addition to prasugrel, Lilly has seven other NMEs
or NME-like therapies in Phase III trials or pending
regulatory approval, including potential new treatments
for osteoporosis, diabetes, multiple sclerosis, and non-
Hodgkin’s lymphoma, an inhaled version of insulin, a
weekly formulation of Byetta, and a long-acting injectable
form of Zyprexa. Lilly also has more than a dozen new
indications, line extensions, and delivery devices in Phase
III trials or under regulatory review.
If successful, most of those therapies will be approved
between 2008 and 2011, further strengthening Lilly’s prod-
uct portfolio as older patents expire. At the same time, Lilly
has the strongest mid-stage pipeline of molecules in its his-
tory, and we are accelerating the development of some of
them in a concerted strategy. As a result, Lilly should have
at least 10 NMEs in Phase III trials by 2011—with the goal
of launching two novel medicines per year starting at that
time, increasing to three per year in 2014.
Business Development
On the basis of increasing cash flow, Lilly invested
nearly $3 billion in acquisitions and licensing during
4
2007 to strengthen our sales performance and our R&D
pipeline. Most prominently, our successful integration
of ICOS’s operations allowed us to realize considerable
efficiencies in the selling and marketing of Cialis—which
posted a 25 percent increase in worldwide sales in 2007,
to $1.216 billion.
Lilly’s acquisition of Hypnion in 2007 gave us access
to a promising new compound for sleep disorders as well
as a broader presence in this area of research. In addition,
we entered into licensing agreements with OSI Phar-
maceuticals and MacroGenics to gain access to exciting
compounds and research platforms focused on diabetes
and various autoimmune diseases, with Glenmark Phar-
maceuticals to obtain the rights to a portfolio of potential
pain-fighting compounds, and with BioMS Medical on a
potential therapy for multiple sclerosis.
Growing cash flow also allowed us to increase our
quarterly dividend in the fourth quarter of 2007 by
almost 11 percent, and it will give us continued freedom
to seek growth opportunities and improved pipeline value
through acquisitions and licensing in the years ahead.
Transformation
Earlier, we referred to Lilly’s vision of becoming a
truly patient-centered enterprise, focused on optimiz-
ing individual patient outcomes. While we realize that
the achievement of this vision will take many years, we
were pleased that 2007 brought early, tangible evidence
of Lilly’s transformation into a company that offers an
unmistakable value proposition to the people who depend
on its products.
For example, the effort to “tailor” our medicines to
individual patients’ needs—delivering the right drug at
the right dose at the right time—is bearing fruit. This will
lead to a clearer benefit/risk understanding for patients,
doctors, and payers alike—based on a higher degree of
confidence that a medicine will work effectively and with
manageable side effects.
Lilly’s large clinical trial of prasugrel is a great ex-
ample. Completed in 2007, the so-called TRITON study
yielded robust data on patients for whom the benefits of
prasugrel clearly outweigh the risks; patients who ben-
efited from the drug but who also had increased risk of
bleeding (and might therefore be best served by a lower
dose); and the small percentage of patients who did not
appear to gain greater benefit from prasugrel compared to
the potential risk.
Lilly also has made considerable progress in trans-
forming itself from a fully-integrated pharmaceutical com-
pany—the old “FIPCO” model—into what we refer to as
a fully-integrated pharmaceutical network—or “FIPNET.”
In the new model, we draw on a broad range of resources
outside our company’s walls—to increase our effective
capacity and access to external capabilities, to reduce our
level of risk and accelerate development, and ultimately to
help lower our average cost of R&D per molecule.
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Some of this transformation involves fairly traditional
outsourcing—for example, the early-stage development
work of our ChemExplorer and PharmExplorer partner-
ships in China; and our discovery efforts with Jubilant in
India. At the same time, however, we are pioneering new
ways to share risks and rewards, such as our partnership
with Nicholas Piramal. In exchange for milestone pay-
ments, and a royalty if a product reaches the market, this
India-based company is developing selected molecules
from our pipeline up to the end of Phase II—during
which time we may opt to bring them back into our Lilly
portfolio. Lilly has a similar risk-sharing collaboration
with Suven Pharmaceuticals in Hyderabad, which will be
expanded in 2008. And we have entered into a partnership
in the preclinical arena with China’s Hutchison MediPhar-
ma, focused on targets in oncology and infl ammation.
The emergence of Lilly as the hub of a “FIPNET”
should contribute as well to our productivity gains across
the business. Since 2003, Lilly has reduced its headcount
by about 11 percent worldwide, increased its net sales
per employee by 64 percent, improved gross margin as a
percent of sales, and reduced manufacturing, R&D, and ad-
ministrative infrastructure while increasing overall output.
More than ever, Six Sigma is an invaluable disci-
pline at Lilly, as an important driver of productivity and
broader transformation. Since we started applying Six
Sigma in 2005, Lilly has completed some 2,000 projects
that are having an impact not just on expenses but also
on improving sales, cutting R&D cycle times, and indeed
improving all aspects of the business.
Jamming
Clearly, 2007 would have left us with very favorable
memories in any case at Lilly—as a year of breakout per-
formance and increased confi dence in our transformation.
The year ended on a particularly hopeful note, however,
with a global “Vision Jam” involving more than 22,000
Lilly employees and contractors. Facilitated by IBM, the
four-day, round-the-clock event brought together Lilly
people in an online setting to brainstorm new ideas and
explore them in an uninhibited way. The Jam left Lilly
with literally thousands of fresh ideas, discussion threads,
and well-argued debates focused on our transformation.
Many of the ideas will be implemented before this report
goes to press—and many more will follow quickly.
The Jam also left us more convinced than ever that
Lilly has the necessary creativity and commitment among
its people to exceed the expectations of our customers.
The diffi cult nature of Lilly’s external environment
has not changed in the last year. Populations, on aver-
age, are healthier and getting older throughout most of
the world, driving demand for health care and therefore
its overall cost. Prescription medicines generally account
for a small share of total health care spending by govern-
ments and private insurers—and the use of our products
often reduces spending on more expensive forms of treat-
ment. Nevertheless, the pharmaceutical industry regularly
experiences acute pressure on our reimbursement levels
and market access almost everywhere we do business to-
day. Unfortunately, we are often viewed as an easy target
in attempts to limit spending in the near term or to assign
blame for the inevitable shortcomings of health care sys-
tems overall. At the same time, the growing expectations
of industry regulators have only added to the expense and
complexity of pharmaceutical R&D.
At Lilly, we have chosen to regard such environmen-
tal realities not as excuses for decline but as motivators
for our own performance and ongoing transformation.
We cannot eliminate the underlying conditions that keep
the pharmaceutical industry under pressure and scrutiny.
But we can control our own expenses and improve the
way we work. We can harness what we are learning about
human biology to improve the effi cacy and the benefi t-
risk profi les of products coming through our pipeline. We
can do many things to improve how patients are diag-
nosed and therapies are used. We can help to improve pa-
tients’ access to our products and to build understanding
of our business practices through transparency. And we
can take on more responsibility for the health care chal-
lenges facing society as a whole, as our corporate social
responsibility report (see page 9) demonstrates.
If we do these things—and do them well—then Lilly
will realize its vision of improving outcomes for individu-
al patients even as we secure our own bright future.
For the Board of Directors,
Sidney Taurel
Chairman of the Board and Chief Executive Offi cer
John C. Lechleiter
President and Chief Operating Offi cer
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Innovation at Lilly: The Portfolio and the Pipeline
Major Marketed Products (Dates indicate the year of first global launch)
2005
Byetta®
for type 2 diabetes
for use in combination with a thiazolidinedione (2007)
(in collaboration with Amylin Pharmaceuticals, Inc.)
2004
Cymbalta®
for major depressive disorder
for diabetic peripheral neuropathic pain (2004)
for generalized anxiety disorder (2007)
for the maintenance treatment of major depressive disorder (2007)
(in collaboration with Quintiles Transnational Corp. in the U.S., Shionogi & Co. Ltd. in
Japan, and with Boehringer Ingelheim elsewhere in the world)
2004
Alimta®
for malignant pleural mesothelioma
for second-line treatment of non-small cell lung cancer (2004)
2004
2004
2003
Symbyax®
for bipolar depression
Yentreve®
for stress urinary incontinence (approved and launched outside the U.S.)
Cialis®
for erectile dysfunction
for once-daily use (2007)
2003
Strattera®
for attention-deficit hyperactivity disorder in children, adolescents, and adults
2002
Forteo®
for treatment of men and postmenopausal women with osteoporosis who are at
high risk for a fracture
2001
Xigris®
for severe sepsis in adult patients at high risk of death
1999
Actos®
for type 2 diabetes
(in collaboration with Takeda outside the U.S.)
1998
Evista®
1996
Zyprexa®
for prevention of osteoporosis in postmenopausal women
for treatment of osteoporosis in postmenopausal women (1999)
for reduction in risk of invasive breast cancer in postmenopausal women with
osteoporosis (2007)
for reduction in risk of invasive breast cancer in postmenopausal women at high risk for
invasive breast cancer (2007)
for schizophrenia
for acute bipolar mania (2000)
Zyprexa® Zydis® tablet (2000)
for schizophrenia maintenance (2001)
as combination therapy with lithium or valproate for acute bipolar mania (2002)
for bipolar maintenance (2003)
Rapid-acting IntraMuscular formulation (2004)
Zyprexa® granules (2004; launched in Japan only)
1996
Humalog®
Lyspro Rapid Acting Insulin for treatment of type 1 and type 2 diabetes
Humalog® Mix 75/25 (1999)
Humalog® Mix 50/50 (1999)
1995
Gemzar®
6
for non-small-cell lung cancer
for pancreatic cancer (1996)
for bladder cancer (1999; approved and launched outside the U.S.)
for metastatic breast cancer (2003)
for recurrent ovarian cancer (2004)
for biliary tract cancer (2006; Japan)
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ReoPro®
for prevention of cardiac ischemic complications in patients undergoing
coronary intervention, such as angioplasty
for unstable angina associated with stent procedure (1997)
(in collaboration with Centocor, except in Japan)
1987
Humatrope®
for growth failure caused by pediatric growth hormone defi ciency
for replacement therapy for adult growth hormone defi ciency (1995)
for short stature caused by Turner syndrome (1997)
for idiopathic short stature (2003)
1983
Humulin®
for type 1 and type 2 diabetes
New Drug Applications Submitted For Review to the U.S. Food and Drug Administration
Duloxetine
Olanzapine
for fi bromyalgia
for adolescent schizophrenia and bipolar disorder
Olanzapine LAI
long-acting injection delivery for schizophrenia
Olanzapine-Fluoxetine
for treatment-resistant depression
Pemetrexed disodium
for fi rst-line treatment of non-small-cell lung cancer
Prasugrel
for prevention/reduction of atherothrombotic events in patients with acute coronary
syndromes who undergo percutaneous coronary intervention (PCI)
(in collaboration with Daiichi Sankyo Company, Ltd.)
Ruboxistaurin mesylate
for diabetic retinopathy
Teriparatide (rDNA origin) for glucocorticoid-induced osteoporosis (GIOP)
injection
Select Drug Candidates in Late-Stage Investigation
Arzoxifene
for the prevention and treatment of osteoporosis and breast cancer risk reduction
AIR® Inhaled insulin
for type 1 and type 2 diabetes
(in collaboration with Alkermes, Inc.)
Duloxetine
Enzastaurin
Exenatide
MBP8208
Teplizumab
(continued next page)
for chronic pain
for poor prognosis patients with diffuse large B-cell lymphoma
for once-weekly dosing
for secondary progressive multiple sclerosis (SPMS) and relapsing-remitting multiple
sclerosis (RRMS)
(in collaboration with BioMS Medical Corp.)
for type 1 diabetes
(in collaboration with MacroGenics)
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Select Drug Candidates in Mid-Stage Investigation
A-beta antibody
for Alzheimer’s disease
A-beta lowering
(Gamma secretase inhibitor)
for Alzheimer’s disease
Anti-CD20 (AME133v)
for non-Hodgkin’s lymphoma (NHL)
ASAP
for solid tumors
Factor Xa inhibitor
for venous thromboembolism (VTE) prophylaxis, VTE treatment and atrial fibrillation
stroke prophylaxis
Gemcitabine prodrug
for solid tumors
GLP-Fc analog
for type 2 diabetes
Glucokinase activator
for type 2 diabetes
(in collaboration with OSI Pharmaceuticals, Inc.)
HY10275
for insomnia
IL-1 beta antibody
for rheumatoid arthritis
LP10152 (FGF-21)
for diabetes
mGlu2/3 prodrug
for schizophrenia
NERI IV
OpRA II
for depression (phase II); for ADHD (phase I)
for alcohol dependence
Survivin ASO
for solid tumors
TRPV1 antagonist
for treatment for various pain conditions, including osteoarthritic pain
(in collaboration with Glenmark Pharmaceuticals)
Information is current as of January 31, 2008. The search for new drugs is risky and uncertain, and there are no guarantees.
Remaining scientific and regulatory hurdles may cause pipeline compounds to be delayed or even to fail to reach the market.
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Beyond Medicine: Providing Answers That Matter
Throughout our history, Lilly has been a leading corporate
citizen. While our greatest contributions to society are
breakthrough medicines for patients around the world,
we realize that positive patient outcomes are about more
than just medicine.
At Lilly, our corporate responsibility is focused on
making a measurable difference in business and soci-
ety. We are committed to operating our business at the
highest standards, including being an industry leader in
transparency, using our resources to strengthen the com-
munities in which we live and work, and looking beyond
our operations to help address health challenges.
While we regard this as a journey, we are proud of
our record as a global corporate citizen. Here are some
examples:
Commitment to Transparency
We continue to be an industry leader in transparency.
In 2004, we were the fi rst pharmaceutical company to
publish online the results of all our clinical trials. We have
an unwavering commitment to publicly disclosing medi-
cal research results—whether favorable or unfavorable
for Lilly—in an accurate, objective, and balanced manner
to ensure our customers have the information they need
about our products.
In addition, in 2007 Lilly became the fi rst pharmaceu-
tical company to disclose publicly all of our grants to U.S.
nongovernmental organizations, research institutions,
and others. This information is available online at www.
lillygrantoffi ce.com.
Philanthropy and Community Support
Lilly also continues to build on its long tradition
of philanthropy and community support. According to
the Chronicle of Philanthropy, the company’s 2006 giv-
ing placed it sixth among the 91 major U.S. companies
responding to its survey. In 2007, our philanthropic
contributions totaled about $315 million, including about
$240 million in products for patient assistance programs
and international humanitarian causes. Our total 2007
giving represents about 6 percent of our adjusted income
before taxes and has positioned Lilly once again as one of
the most charitable companies in the world.
We also launched a new employee volunteer initia-
tive called “Hands and Hearts,” which aims to enhance
employee involvement with nonprofi t organizations while
allowing us to track and measure results. By encouraging
volunteerism, we strengthen our communities and in-
crease the commitment and engagement of our workforce.
Improving Access to Medicines
Access to health care—and to affordable medicines—
is a major problem in many countries, and Lilly has taken
steps to assist. For example, in 2007, we helped more than
145,000 patients in the U.S. obtain medicines through six
different assistance programs. These programs are part of
a broader industry effort. Through the Partnership for Pre-
scription Assistance program (PPARx), the pharmaceutical
industry has helped more than 4 million people get afford-
able access to needed medicines. Additional information
on PPARx may be found at www.pparx.org.
Fighting Multidrug-Resistant Tuberculosis (MDR-TB)
MDR-TB is a growing global health threat. Begun in
2003, Lilly’s groundbreaking MDR-TB Partnership seeks to
increase the supply and availability of two important medi-
cines to treat the deadly disease in the hardest-hit countries.
In March 2007, we increased our fi nancial commitment
by an additional $50 million. And in June, we announced
the creation of an ambitious public–private consortium in
Seattle to conduct early-phase discovery research of new
medicines urgently needed to treat tuberculosis, including
emerging resistant strains, with another $15 million invest-
ment—bringing our total contributions to $135 million. In
2007, our efforts were recognized by the Global Business
Coalition, which described our MDR-TB program as a “su-
perlative model” for other businesses to follow.
Supporting Novel Approaches in the Battle Against
Diabetes
In keeping with Lilly’s strong and historic commit-
ment to diabetes, the Lilly Foundation is contributing up
to $15 million to the American Academy of Family Physi-
cians Foundation to establish “Peers for Progress,” a pro-
gram that will identify and train lay volunteers who have
diabetes and empower them to be “diabetes mentors.”
These mentors will then assist other people with diabetes
to better manage the emotional, social, and daily self-
care demands of the disease. The goal of this ambitious
initiative is to empower 200,000 volunteers, or 1 percent
of Americans with diabetes, to become diabetes mentors
and to expand this program globally. In addition, Lilly is
providing an educational grant of $10 million to the Inter-
national Diabetes Federation to fund “Project BRIDGES,” a
global effort to identify and share successful strategies for
managing diabetes.
For a full report on Lilly’s corporate citizenship initiatives,
please visit www.lilly.com/about/citizenship.
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Review of Operations
EXECUTIVE OVERVIEW
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This section provides an overview of our fi nancial re-
sults, signifi cant business development, recent product
and late-stage pipeline developments, and legal, regu-
latory, and other matters affecting our company and the
pharmaceutical industry.
Financial Results
We achieved worldwide sales growth of 19 percent. This
growth was primarily driven by volume increases in a
number of key products, with a signifi cant portion of
this increase in volume resulting from the acquisition
of ICOS. Our additional investments in marketing and
selling expenses in support of key products, primarily
Cymbalta® and the diabetes care products, contributed
to this sales growth and enabled us to increase our
investment in research and development 11 percent
in 2007. While cost of sales and operating expenses in
the aggregate grew at approximately the same rate as
sales, other income—net decreased and the effective
tax rate increased. As a result, net income and earn-
ings per share increased 11 percent, to $2.95 billion, or
$2.71 per share, in 2007 as compared with $2.66 billion,
or $2.45 per share, in 2006. Net income comparisons
between 2007 and 2006 are affected by the impact of
the following signifi cant items that are refl ected in our
fi nancial results (see Notes 3, 4, and 13 to the consoli-
dated fi nancial statements for additional information):
2007
• We recognized asset impairments, restructuring,
and other special charges of $98.2 million (pretax)
in the fourth quarter, which decreased earnings per
share by $.07. In the fi rst quarter, we recognized
similar charges associated with previously announced
strategic decisions affecting manufacturing and
research facilities of $123.0 million (pretax), which
decreased earnings per share by $.08 (Note 4).
• We incurred a special charge following a settlement
with one of our insurance carriers over Zyprexa®
product liability claims, which led to a reduction of our
expected product liability insurance recoveries. This
resulted in a charge of $81.3 million (pretax), which
decreased earnings per share by $.06 in the third
quarter (Notes 4 and 13).
• We incurred in-process research and development
(IPR&D) charges associated with our licensing
arrangement with Glenmark Pharmaceuticals Limited
India of $45.0 million (pretax) and our licensing
arrangement with MacroGenics, Inc., of $44.0 million
(pretax), which decreased earnings per share by $.05 in
the fourth quarter (Note 3).
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• We incurred IPR&D charges associated with the
acquisition of Hypnion, Inc. (Hypnion), of $291.1 million
(no tax benefi t) and the acquisition of Ivy Animal
Health, Inc. (Ivy), of $37.0 million (pretax), which
decreased earnings per share by $.29 in the second
quarter (Note 3).
• We incurred IPR&D charges associated with the
acquisition of ICOS of $303.5 million (no tax benefi t)
and a licensing arrangement with OSI Pharmaceuticals
of $25.0 million (pretax), which decreased earnings per
share by $.29 in the fi rst quarter (Note 3).
2006
• We recognized asset impairments, restructuring, and
other special charges of $450.3 million (pretax) in the
fourth quarter, which decreased earnings per share by
$.31 (Note 4).
• In the fourth quarter, we incurred a charge related to
Zyprexa product liability litigation matters of $494.9 mil-
lion (pretax), or $.42 per share (Notes 4 and 13).
Late-Stage Pipeline Developments and Business
Development Activity
Our long-term success depends, to a great extent, on
our ability to continue to discover and develop innova-
tive pharmaceutical products and acquire or collabo-
rate on compounds currently in development by other
biotechnology or pharmaceutical companies. We have
achieved a number of successes with late-stage pipe-
line developments and recent business development
transactions within the past year, including:
Pipeline
• On December 26, 2007, together with our collaboration
partner Daiichi Sankyo Company, Limited, we
submitted a New Drug Application (NDA) for prasugrel
to the U.S. Food and Drug Administration (FDA). The
proposed trademark for prasugrel is Effi ent™. The
submission follows the release of results of the
TRITON TIMI-38 Phase III head-to-head study of
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prasugrel versus clopidogrel in November.
• In January 2008, the FDA approved Cialis® for once-
daily use to treat erectile dysfunction. Cialis was
approved by the European Commission for once-daily
use in June 2007.
• In November, the FDA approved Cymbalta for the
maintenance treatment of major depressive disorder in
adults. In February, the FDA approved Cymbalta for the
treatment of generalized anxiety disorder. During 2007,
we submitted a Supplemental New Drug Application
to the FDA for Cymbalta for the management of
fi bromyalgia.
• In October, with our collaboration partners Amylin
Pharmaceuticals, Inc., and Alkermes, Inc., we
announced positive results from a 30-week comparator
study of once-weekly exenatide long-acting release
injection and Byetta® (exenatide) injection taken twice
daily in patients with type 2 diabetes.
• In the second quarter, we submitted NDAs to the
FDA and the European Medicines Agency (EMEA) for
approval of olanzapine (Zyprexa) long-acting injection.
• In September, the FDA approved Evista® for a new
use to reduce the risk of invasive breast cancer
in two populations: postmenopausal women with
osteoporosis and postmenopausal women at high risk
for invasive breast cancer.
• We submitted an application to the EMEA for
centralized review of Alimta®, in combination with
cisplatin, for the fi rst-line treatment of non-small cell
lung cancer.
autoimmune diseases. As part of the arrangement,
we acquired the exclusive rights to the molecule.
Teplizumab is currently being studied in the PROTÉGÉ
trial, a global pivotal Phase II/III clinical trial for
individuals with recent-onset type 1 diabetes.
• In June, we completed the acquisition of Ivy Animal
Health, Inc., a privately held applied research and
pharmaceutical product development company focused
on the animal health industry. The acquisition provides
us with product lines that complement those of our
animal health business.
• In April, we completed the acquisition of Hypnion,
Inc., a privately held neuroscience drug discovery
company focused on sleep disorders. The deal expands
our presence in the area of sleep disorder research
and provides ownership of a novel Phase II insomnia
compound with a dual mechanism of action aimed at
promoting better sleep onset and sleep maintenance.
• In January, we completed the acquisition of ICOS at
a cost of approximately $2.3 billion. The acquisition
brings the full value of Cialis to us and enables us
to realize operational effi ciencies in the further
development, marketing, and selling of this product.
• In January, we licensed from OSI Pharmaceuticals its
glucokinase activator (GKA) program for the treatment
of type 2 diabetes, including the lead compound. Lilly
received an exclusive license to develop and market
any compounds derived from the GKA program.
LEGAL, REGULATORY, AND OTHER MATTERS
Business Development
• In December, we entered into a licensing and
development agreement with BioMS Medical Corp.
whereby we acquired exclusive worldwide rights to
a multiple sclerosis (MS) compound. The compound
is currently being evaluated in two pivotal Phase III
clinical trials in secondary progressive MS (SPMS) and
one Phase II clinical trial in relapsing-remitting MS
(RRMS). In connection with this agreement, we will
incur a charge to earnings for acquired IPR&D of $87.0
million (pretax), which will be included as expense in
the fi rst quarter of 2008.
• In October, we entered into an agreement with
Glenmark Pharmaceuticals Limited India whereby we
acquired the rights to a portfolio of transient receptor
potential vanilloid sub-family 1 (TRPV1) antagonist
molecules, including a clinical-phase compound. The
compound is currently in Phase II development as a
potential next-generation treatment for various pain
conditions, including osteoarthritic pain.
• In October, we entered into a global strategic alliance
with MacroGenics, Inc., to develop and commercialize
teplizumab, a humanized anti-CD3 monoclonal
antibody, as well as other potential next-generation
anti-CD3 molecules for use in the treatment of
In October, the United States Supreme Court denied the
petitions for certiorari that were fi led by Teva Phar-
maceuticals and Dr. Reddy’s Laboratories, bringing to
an end the two companies’ challenges to the validity of
Lilly’s U.S. Zyprexa patent.
In June, we received notice of two court rulings
by the Canadian Federal Court and the German Pat-
ent Court that permit the entry of generic olanzapine
(Zyprexa) by competitors into the Canadian and German
markets. Generic olanzapine is now available for sale
by competitors in Canada and Germany.
We have reached agreements with claimants’
attorneys involved in U.S. Zyprexa product liability
litigation to settle a total of approximately 31,200 claims
against us relating to the medication. Approximately
1,235 claims remain. As a result of our product liability
exposures, since the beginning of 2005, we have re-
corded aggregate net pretax charges of $1.61 billion for
Zyprexa product liability matters.
In March 2004, we were notifi ed by the U.S. Attor-
ney’s offi ce for the Eastern District of Pennsylvania
(EDPA) that it had commenced an investigation relating
to our U.S. marketing and promotional practices for
Zyprexa, Prozac®, and Prozac Weekly™. In November
2007, we received a grand jury subpoena from the EDPA
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requesting documents related to Zyprexa.
In the United States, the Medicare Prescription
Drug, Improvement, and Modernization Act of 2003
(MMA) continues to effectively provide a prescription
drug benefi t under the Medicare program (known as
Medicare Part D). Various measures have been dis-
cussed and/or passed in both the U.S. House of Repre-
sentatives and U.S. Senate that would impose additional
pricing pressures on our products, including proposals
to legalize the importation of prescription drugs and
either allow, or require, the Secretary of Health and Hu-
man Services to negotiate drug prices within Medicare
Part D directly with pharmaceutical manufacturers.
Additionally, various proposals have been introduced
that would increase the rebates we pay on sales to
Medicaid patients. We expect pricing pressures at the
federal and state levels to continue.
In 2007, the Centers for Medicare and Medicaid
Services released a fi nal rule seeking to implement
sections of the Defi cit Reduction Act of 2005. This rule
relates to the Medicaid program and among other
things, sets out a methodology for the calculation and
use of Average Manufacturer Price and Best Price for
pharmaceuticals. We have implemented the fi nal rule,
which has the effect of reducing net selling prices for
Medicaid sales; however, we do not expect the impact
to be material to our consolidated results of operations,
liquidity, or fi nancial position.
International operations also are generally subject
to extensive price and market regulations, and there
are many proposals for additional cost-containment
measures, including proposals that would directly or
indirectly impose additional price controls or reduce the
value of our intellectual property protection.
OPERATING RESULTS—2007
Sales
Our worldwide sales for 2007 increased 19 percent, to
$18.63 billion, driven primarily by the inclusion of Cialis
since our January 29, 2007 acquisition of ICOS and
sales growth of Cymbalta, Zyprexa, Alimta, Gemzar®,
and Humalog®. Worldwide sales volume increased 12
percent, while selling prices and foreign exchange rates
each increased sales by 3 percent. (Numbers do not add
due to rounding.) Sales in the U.S. increased 18 percent,
to $10.15 billion, driven primarily by increased sales of
Cymbalta, Zyprexa, Alimta, and Byetta, and the inclu-
sion of Cialis. Sales outside the U.S. increased 20 per-
cent, to $8.49 billion, driven primarily by the inclusion
of Cialis, and sales growth of Zyprexa, Alimta, Gemzar,
and Cymbalta.
Zyprexa, our top-selling product, is a treatment for
schizophrenia, acute mixed or manic episodes associ-
ated with bipolar I disorder and bipolar maintenance.
Zyprexa sales in the U.S. increased 6 percent in 2007,
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(cid:14)(cid:134)(cid:122)(cid:131)(cid:205)(cid:202)(cid:168)(cid:192)(cid:156)(cid:94)(cid:210)(cid:83)(cid:205)(cid:196)(cid:110)(cid:10)(cid:219)(cid:148)(cid:74)(cid:58)(cid:143)(cid:205)(cid:58)(cid:91)(cid:202)(cid:57)(cid:219)(cid:168)(cid:192)(cid:103)(cid:218)(cid:58)(cid:91)(cid:202)(cid:10)(cid:134)(cid:58)(cid:143)(cid:134)(cid:196)(cid:91)(cid:202)
(cid:1)(cid:143)(cid:134)(cid:148)(cid:205)(cid:58)(cid:91)(cid:202)(cid:20)(cid:103)(cid:148)(cid:222)(cid:58)(cid:192)(cid:91)(cid:202)(cid:21)(cid:210)(cid:148)(cid:58)(cid:143)(cid:156)(cid:122)(cid:91)(cid:202)(cid:19)(cid:156)(cid:192)(cid:205)(cid:103)(cid:156)(cid:91)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)
(cid:9)(cid:219)(cid:103)(cid:205)(cid:205)(cid:58)(cid:110)(cid:122)(cid:103)(cid:151)(cid:103)(cid:192)(cid:58)(cid:205)(cid:103)(cid:94)(cid:202)(cid:100)(cid:163)(cid:206)(cid:174)(cid:223)(cid:202)(cid:74)(cid:134)(cid:143)(cid:143)(cid:134)(cid:156)(cid:151)(cid:202)(cid:134)(cid:151)(cid:202)(cid:151)(cid:103)(cid:205)(cid:202)(cid:196)(cid:58)(cid:143)(cid:103)(cid:196)(cid:202)
(cid:94)(cid:210)(cid:192)(cid:134)(cid:151)(cid:122)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:91)(cid:202)(cid:58)(cid:151)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:202)(cid:156)(cid:115)(cid:202)(cid:100)(cid:209)(cid:174)(cid:152)(cid:202)(cid:74)(cid:134)(cid:143)(cid:143)(cid:134)(cid:156)(cid:151)(cid:202)(cid:156)(cid:216)(cid:103)(cid:192)(cid:202)
(cid:209)(cid:223)(cid:223)(cid:200)(cid:174)(cid:202)(cid:1)(cid:196)(cid:196)(cid:210)(cid:148)(cid:134)(cid:151)(cid:122)(cid:202)(cid:156)(cid:210)(cid:192)(cid:202)(cid:58)(cid:83)(cid:181)(cid:210)(cid:134)(cid:196)(cid:134)(cid:205)(cid:134)(cid:156)(cid:151)(cid:202)(cid:156)(cid:115)(cid:202)(cid:22)(cid:10)(cid:33)(cid:45)(cid:202)
(cid:156)(cid:83)(cid:83)(cid:210)(cid:192)(cid:192)(cid:103)(cid:94)(cid:202)(cid:156)(cid:151)(cid:202)(cid:27)(cid:58)(cid:151)(cid:210)(cid:58)(cid:192)(cid:219)(cid:202)(cid:163)(cid:91)(cid:202)(cid:209)(cid:223)(cid:223)(cid:200)(cid:91)(cid:202)(cid:205)(cid:131)(cid:103)(cid:196)(cid:103)(cid:202)(cid:103)(cid:134)(cid:122)(cid:131)(cid:205)(cid:202)
(cid:168)(cid:192)(cid:156)(cid:94)(cid:210)(cid:83)(cid:205)(cid:196)(cid:202)(cid:122)(cid:103)(cid:151)(cid:103)(cid:192)(cid:58)(cid:205)(cid:103)(cid:94)(cid:202)(cid:58)(cid:151)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:202)(cid:156)(cid:115)(cid:202)(cid:100)(cid:209)(cid:174)(cid:206)(cid:202)(cid:74)(cid:134)(cid:143)(cid:143)(cid:134)(cid:156)(cid:151)(cid:202)
(cid:156)(cid:216)(cid:103)(cid:192)(cid:202)(cid:209)(cid:223)(cid:223)(cid:200)(cid:174)(cid:202)(cid:46)(cid:131)(cid:134)(cid:196)(cid:202)(cid:122)(cid:192)(cid:156)(cid:217)(cid:205)(cid:131)(cid:202)(cid:217)(cid:58)(cid:196)(cid:202)(cid:168)(cid:192)(cid:134)(cid:148)(cid:58)(cid:192)(cid:134)(cid:143)(cid:219)(cid:202)(cid:94)(cid:192)(cid:134)(cid:216)(cid:103)(cid:151)(cid:202)
(cid:74)(cid:219)(cid:202)(cid:216)(cid:156)(cid:143)(cid:210)(cid:148)(cid:103)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:196)(cid:174)(cid:202)(cid:10)(cid:134)(cid:58)(cid:143)(cid:134)(cid:196)(cid:202)(cid:196)(cid:58)(cid:143)(cid:103)(cid:196)(cid:202)(cid:196)(cid:131)(cid:156)(cid:217)(cid:151)(cid:202)
(cid:58)(cid:196)(cid:196)(cid:210)(cid:148)(cid:103)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:58)(cid:83)(cid:181)(cid:210)(cid:134)(cid:196)(cid:134)(cid:205)(cid:134)(cid:156)(cid:151)(cid:202)(cid:156)(cid:115)(cid:202)(cid:22)(cid:10)(cid:33)(cid:45)(cid:202)(cid:156)(cid:83)(cid:83)(cid:210)(cid:192)(cid:192)(cid:103)(cid:94)(cid:202)
(cid:156)(cid:151)(cid:202)(cid:27)(cid:58)(cid:151)(cid:210)(cid:58)(cid:192)(cid:219)(cid:202)(cid:163)(cid:91)(cid:202)(cid:209)(cid:223)(cid:223)(cid:200)(cid:174)(cid:202)(cid:33)(cid:151)(cid:202)(cid:58)(cid:151)(cid:202)(cid:58)(cid:196)(cid:202)(cid:192)(cid:103)(cid:168)(cid:156)(cid:192)(cid:205)(cid:103)(cid:94)(cid:202)(cid:74)(cid:58)(cid:196)(cid:134)(cid:196)(cid:91)(cid:202)
(cid:10)(cid:134)(cid:58)(cid:143)(cid:134)(cid:196)(cid:202)(cid:196)(cid:58)(cid:143)(cid:103)(cid:196)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:94)(cid:202)(cid:100)(cid:152)(cid:209)(cid:108)(cid:174)(cid:223)(cid:202)(cid:148)(cid:134)(cid:143)(cid:143)(cid:134)(cid:156)(cid:151)(cid:202)(cid:134)(cid:151)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:202)
(cid:58)(cid:196)(cid:202)(cid:83)(cid:156)(cid:148)(cid:168)(cid:58)(cid:192)(cid:103)(cid:94)(cid:202)(cid:205)(cid:156)(cid:202)(cid:209)(cid:223)(cid:223)(cid:200)(cid:174)(cid:202)
(cid:26)
(cid:37)
(cid:43)
(cid:32)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:44)
(cid:45)
(cid:44)
(cid:25)
(cid:26)
(cid:46)
(cid:32)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:44)
(cid:46)
(cid:40)
(cid:25)
(cid:26)
(cid:42)
(cid:39)
(cid:32)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:43)
(cid:41)
(cid:39)
(cid:25)
(cid:26)
(cid:37)
(cid:41)
(cid:32)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:39)
(cid:41)
(cid:39)
(cid:25)
(cid:26)
(cid:40)
(cid:38)
(cid:32)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:41)
(cid:45)
(cid:38)
(cid:25)
(cid:26)
(cid:40)
(cid:38)
(cid:32)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:42)
(cid:44)
(cid:38)
(cid:25)
(cid:26)
(cid:46)
(cid:38)
(cid:32)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:42)
(cid:38)
(cid:38)
(cid:25)
(cid:26)
(cid:38)
(cid:42)
(cid:32)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:39)
(cid:38)
(cid:38)
(cid:25)
(cid:86)
(cid:109)
(cid:90)
(cid:103)
(cid:101)
(cid:110)
(cid:79)
(cid:86)
(cid:105)
(cid:97)
(cid:86)
(cid:87)
(cid:98)
(cid:110)
(cid:56)
(cid:104)
(cid:94)
(cid:97)
(cid:86)
(cid:56)
(cid:94)
(cid:86)
(cid:105)
(cid:98)
(cid:94)
(cid:97)
(cid:54)
(cid:103)
(cid:86)
(cid:111)
(cid:98)
(cid:90)
(cid:60)
(cid:92)
(cid:100)
(cid:97)
(cid:86)
(cid:98)
(cid:106)
(cid:61)
(cid:100)
(cid:90)
(cid:105)
(cid:103)
(cid:100)
(cid:59)
(cid:86)
(cid:105)
(cid:105)
(cid:90)
(cid:110)
(cid:55)
driven by higher net selling prices, partially offset by
lower demand. Sales outside the U.S. increased 12 per-
cent, driven by the favorable impact of foreign exchange
rates and increased demand.
Sales of Cymbalta, a product for the treatment
of major depressive disorder, diabetic peripheral
neuropathic pain, and generalized anxiety disorder,
increased 58 percent in the U.S., driven primarily by
strong demand. Sales outside the U.S. increased 70
percent, driven by increased demand and the favorable
impact of foreign exchange rates.
Sales of Gemzar, a product approved to fi ght vari-
ous cancers, increased 10 percent in the U.S., driven by
higher prices and increased demand. Sales outside the
U.S. increased 16 percent, driven by increased demand
and the favorable impact of foreign exchange rates.
Sales of Humalog, our injectable human insulin ana-
log for the treatment of diabetes, increased 9 percent in
the U.S., driven by higher prices and increased demand.
Sales outside the U.S. increased 20 percent, driven by
increased demand and the favorable impact of foreign
exchange rates, partially offset by declining prices.
Total worldwide sales of Cialis, a treatment for erec-
(cid:72)(cid:86)(cid:97)(cid:90)(cid:104)(cid:21)(cid:60)(cid:103)(cid:100)(cid:108)(cid:21)(cid:54)(cid:88)(cid:103)(cid:100)(cid:104)(cid:104)(cid:21)(cid:73)(cid:93)(cid:90)(cid:103)(cid:86)(cid:101)(cid:90)(cid:106)(cid:105)(cid:94)(cid:88)(cid:21)(cid:54)(cid:103)(cid:90)(cid:86)(cid:104)
(cid:45)(cid:58)(cid:143)(cid:103)(cid:196)(cid:202)(cid:134)(cid:151)(cid:202)(cid:31)(cid:103)(cid:210)(cid:192)(cid:156)(cid:196)(cid:83)(cid:134)(cid:103)(cid:151)(cid:83)(cid:103)(cid:196)(cid:91)(cid:202)(cid:143)(cid:103)(cid:94)(cid:202)(cid:74)(cid:219)(cid:202)(cid:57)(cid:219)(cid:168)(cid:192)(cid:103)(cid:218)(cid:58)(cid:202)
(cid:58)(cid:151)(cid:94)(cid:202)(cid:10)(cid:219)(cid:148)(cid:74)(cid:58)(cid:143)(cid:205)(cid:58)(cid:91)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:94)(cid:202)(cid:163)(cid:199)(cid:202)(cid:168)(cid:103)(cid:192)(cid:83)(cid:103)(cid:151)(cid:205)(cid:202)(cid:58)(cid:196)(cid:202)
(cid:83)(cid:156)(cid:148)(cid:168)(cid:58)(cid:192)(cid:103)(cid:94)(cid:202)(cid:205)(cid:156)(cid:202)(cid:209)(cid:223)(cid:223)(cid:200)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:192)(cid:103)(cid:168)(cid:192)(cid:103)(cid:196)(cid:103)(cid:151)(cid:205)(cid:202)
(cid:120)(cid:209)(cid:202)(cid:168)(cid:103)(cid:192)(cid:83)(cid:103)(cid:151)(cid:205)(cid:202)(cid:156)(cid:115)(cid:202)(cid:156)(cid:210)(cid:192)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:202)(cid:151)(cid:103)(cid:205)(cid:202)(cid:196)(cid:58)(cid:143)(cid:103)(cid:196)(cid:174)(cid:202)
(cid:14)(cid:151)(cid:94)(cid:156)(cid:83)(cid:192)(cid:134)(cid:151)(cid:156)(cid:143)(cid:156)(cid:122)(cid:219)(cid:91)(cid:202)(cid:143)(cid:103)(cid:94)(cid:202)(cid:74)(cid:219)(cid:202)(cid:21)(cid:210)(cid:148)(cid:58)(cid:143)(cid:156)(cid:122)(cid:91)(cid:202)
(cid:14)(cid:216)(cid:134)(cid:196)(cid:205)(cid:58)(cid:91)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:21)(cid:210)(cid:148)(cid:210)(cid:143)(cid:134)(cid:151)(cid:91)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:94)(cid:202)
(cid:152)(cid:202)(cid:168)(cid:103)(cid:192)(cid:83)(cid:103)(cid:151)(cid:205)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:192)(cid:103)(cid:168)(cid:192)(cid:103)(cid:196)(cid:103)(cid:151)(cid:205)(cid:202)(cid:209)(cid:152)(cid:202)(cid:168)(cid:103)(cid:192)(cid:83)(cid:103)(cid:151)(cid:205)(cid:202)
(cid:156)(cid:115)(cid:202)(cid:156)(cid:210)(cid:192)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:202)(cid:151)(cid:103)(cid:205)(cid:202)(cid:196)(cid:58)(cid:143)(cid:103)(cid:196)(cid:174)(cid:202)(cid:1)(cid:196)(cid:196)(cid:210)(cid:148)(cid:134)(cid:151)(cid:122)(cid:202)
(cid:205)(cid:131)(cid:103)(cid:202)(cid:58)(cid:83)(cid:181)(cid:210)(cid:134)(cid:196)(cid:134)(cid:205)(cid:134)(cid:156)(cid:151)(cid:202)(cid:156)(cid:115)(cid:202)(cid:22)(cid:10)(cid:33)(cid:45)(cid:202)(cid:156)(cid:83)(cid:83)(cid:210)(cid:192)(cid:192)(cid:103)(cid:94)(cid:202)
(cid:156)(cid:151)(cid:202)(cid:27)(cid:58)(cid:151)(cid:210)(cid:58)(cid:192)(cid:219)(cid:202)(cid:163)(cid:91)(cid:202)(cid:209)(cid:223)(cid:223)(cid:200)(cid:91)(cid:202)(cid:10)(cid:58)(cid:192)(cid:94)(cid:134)(cid:156)(cid:216)(cid:58)(cid:196)(cid:83)(cid:210)(cid:143)(cid:58)(cid:192)(cid:202)
(cid:196)(cid:58)(cid:143)(cid:103)(cid:196)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:94)(cid:202)(cid:100)(cid:209)(cid:163)(cid:163)(cid:174)(cid:209)(cid:202)(cid:148)(cid:134)(cid:143)(cid:143)(cid:134)(cid:156)(cid:151)(cid:202)(cid:156)(cid:192)(cid:202)
(cid:163)(cid:120)(cid:202)(cid:168)(cid:103)(cid:192)(cid:83)(cid:103)(cid:151)(cid:205)(cid:202)(cid:58)(cid:196)(cid:202)(cid:83)(cid:156)(cid:148)(cid:168)(cid:58)(cid:192)(cid:103)(cid:94)(cid:202)(cid:205)(cid:156)(cid:202)(cid:209)(cid:223)(cid:223)(cid:200)(cid:174)(cid:202)(cid:202)
(cid:67)(cid:90)(cid:106)(cid:103)(cid:100)(cid:104)(cid:88)(cid:94)(cid:90)(cid:99)(cid:88)(cid:90)
(cid:58)(cid:99)(cid:89)(cid:100)(cid:88)(cid:103)(cid:94)(cid:99)(cid:100)(cid:97)(cid:100)(cid:92)(cid:110)
(cid:68)(cid:99)(cid:88)(cid:100)(cid:97)(cid:100)(cid:92)(cid:110)
(cid:56)(cid:86)(cid:103)(cid:89)(cid:94)(cid:100)(cid:107)(cid:86)(cid:104)(cid:88)(cid:106)(cid:97)(cid:86)(cid:103)
(cid:68)(cid:105)(cid:93)(cid:90)(cid:103)(cid:21)(cid:69)(cid:93)(cid:86)(cid:103)(cid:98)(cid:86)(cid:88)(cid:90)(cid:106)(cid:105)(cid:94)(cid:88)(cid:86)(cid:97)
(cid:54)(cid:99)(cid:94)(cid:98)(cid:86)(cid:97)(cid:21)(cid:61)(cid:90)(cid:86)(cid:97)(cid:105)(cid:93)
(cid:25)(cid:42)(cid:33)(cid:41)(cid:44)(cid:46)(cid:35)(cid:43)
(cid:32)(cid:46)(cid:26)
(cid:25)(cid:39)(cid:33)(cid:41)(cid:41)(cid:43)(cid:35)(cid:41)
(cid:32)(cid:39)(cid:38)(cid:26)
(cid:25)(cid:44)(cid:33)(cid:45)(cid:42)(cid:38)(cid:35)(cid:37)
(cid:32)(cid:38)(cid:44)(cid:26)
(cid:25)(cid:38)(cid:33)(cid:43)(cid:39)(cid:41)(cid:35)(cid:38)
(cid:67)(cid:66)
(cid:25)(cid:46)(cid:46)(cid:42)(cid:35)(cid:45)
(cid:32)(cid:38)(cid:41)(cid:26)
(cid:25)(cid:39)(cid:40)(cid:43)(cid:35)(cid:43)
(cid:34)(cid:39)(cid:43)(cid:26)
F
I
N
A
N
C
I
A
L
S
The following table summarizes our net sales activity in 2007 compared with 2006:
Product
(Dollars in millions)
Zyprexa . . . . . . . . . . . . . . . . . . . . . . .
Cymbalta . . . . . . . . . . . . . . . . . . . . .
Gemzar . . . . . . . . . . . . . . . . . . . . . . .
Humalog . . . . . . . . . . . . . . . . . . . . . .
Cialis2 . . . . . . . . . . . . . . . . . . . . . . . .
Evista . . . . . . . . . . . . . . . . . . . . . . . .
Animal health products . . . . . . . . .
Humulin® . . . . . . . . . . . . . . . . . . . . .
Alimta . . . . . . . . . . . . . . . . . . . . . . . .
Forteo® . . . . . . . . . . . . . . . . . . . . . .
Strattera® . . . . . . . . . . . . . . . . . . . .
Humatrope® . . . . . . . . . . . . . . . . . .
Actos® . . . . . . . . . . . . . . . . . . . . . . .
Byetta . . . . . . . . . . . . . . . . . . . . . . . .
Other pharmaceutical products . .
Total net sales . . . . . . . . . . . . . .
U.S.1
$ 2,236.0
1,835.6
670.0
888.0
423.8
706.1
480.9
365.2
448.0
494.1
464.6
213.6
150.8
316.5
452.3
$10,145.5
Year Ended
December 31, 2007
Outside U.S.
$2,525.0
267.3
922.4
586.6
720.0
384.6
514.9
620.0
406.0
215.2
104.8
227.2
219.8
14.2
760.0
$8,488.0
Total
$ 4,761.0
2,102.9
1,592.4
1,474.6
1,143.8
1,090.7
995.8
985.2
854.0
709.3
569.4
440.8
370.6
330.7
1,212.3
$18,633.5
Year Ended
December 31, 2006
Total
Percent
Change
from 2006
$ 4,363.6
1,316.4
1,408.1
1,299.5
215.8
1,045.3
875.5
925.3
611.8
594.3
579.0
415.6
448.5
219.0
1,373.3
$15,691.0
9
60
13
13
NM
4
14
6
40
19
(2)
6
(17)
51
(12)
19
NM—Not meaningful
1U.S. sales include sales in Puerto Rico.
2Prior to the acquisition of ICOS, the Cialis sales shown in the table above represent results only in the territories in which we marketed
Cialis exclusively. The remaining sales relate to the joint-venture territories of Lilly ICOS LLC (North America, excluding Puerto Rico,
and Europe). Our share of the joint-venture territory sales, net of expenses and income taxes, is reported in other income—net in our
consolidated income statement. Subsequent to the acquisition, all Cialis product sales are reported in our net sales.
tile dysfunction, were $1.22 billion and $971.0 million
during 2007 and 2006, respectively. This includes $72.7
million of sales in the Lilly ICOS joint-venture territo-
ries for the 2007 period prior to the acquisition of ICOS.
Worldwide sales grew 25 percent in 2007. U.S. sales in-
creased 20 percent in 2007, driven by increased demand
and higher prices. Sales outside the U.S. increased 28
percent in 2007, driven by increased demand, the favor-
able impact of foreign exchange rates, and higher prices.
Prior to the ICOS acquisition, Cialis sales in our terri-
tories were reported in net sales, while our 50 percent
share of the joint-venture net income was reported in
other income—net. All sales of Cialis subsequent to the
ICOS acquisition are reported in our net sales.
Sales of Evista, a product for the prevention and
treatment of osteoporosis in postmenopausal women
and for risk reduction of invasive breast cancer in post-
menopausal women with osteoporosis and postmeno-
pausal women at high risk for invasive breast cancer,
increased 6 percent in the U.S., driven by higher prices.
Sales outside the U.S. increased 1 percent, driven by
the favorable impact of foreign exchange rates, partially
offset by lower prices and lower demand.
Sales of Humulin, an injectable human insulin for
the treatment of diabetes, decreased 1 percent in the
U.S., driven by lower demand, partially offset by higher
prices. Sales outside the U.S. increased 11 percent,
driven by increased demand and the favorable impact of
foreign exchange rates, partially offset by lower prices.
Sales of Alimta, a second-line treatment for non-
small cell lung cancer and in combination with another
agent, for the treatment of malignant pleural meso-
thelioma, increased 28 percent in the U.S., driven by
increased demand and to a lesser extent, higher prices.
Sales outside the U.S. increased 55 percent, driven by
increased demand and to a lesser extent, the favorable
impact of foreign exchange rates.
Sales of Forteo, an injectable treatment for osteo-
porosis in postmenopausal women and men at high risk
for fracture, increased 19 percent in the U.S., driven by
higher net selling prices. U.S. sales growth benefi ted
from access to medical coverage through the Medi-
care Part D program and decreased utilization of our
U.S. patient assistance program and to a lesser extent,
increased demand. Sales outside the U.S. increased 21
percent, driven by increased demand and the favorable
impact of foreign exchange rates.
Sales of Strattera, a treatment for attention-defi cit
hyperactivity disorder in children, adolescents, and
adults, decreased 9 percent in the U.S., as a result of
decreased demand. Sales outside the U.S. increased
50 percent, driven by increased demand and the favor-
able impact of foreign exchange rates.
Our revenues from Actos, an oral agent for the
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Consolidated Statements of Income
ELI LILLY AND COMPANY AND SUBSIDIARIES
(Dollars in millions, except per-share data)
Year Ended December 31
2007
2006
2005
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$18,633.5
$15,691.0
$14,645.3
Cost of sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Research and development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Marketing, selling, and administrative . . . . . . . . . . . . . . . . . . . . . . . . .
Acquired in-process research and development (Note 3) . . . . . . . . .
Asset impairments, restructuring, and other special
charges (Note 4) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other income—net. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
4,248.8
3,486.7
6,095.1
745.6
3,546.5
3,129.3
4,889.8
—
302.5
(122.0)
14,756.7
945.2
(237.8)
12,273.0
3,474.2
3,025.5
4,497.0
—
1,245.3
(314.2)
11,927.8
Income before income taxes and cumulative effect
of a change in accounting principle. . . . . . . . . . . . . . . . . . . . . . . . . .
3,876.8
3,418.0
2,717.5
Income taxes (Note 11) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
923.8
755.3
715.9
Income before cumulative effect of a change in accounting
principle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2,953.0
2,662.7
2,001.6
Cumulative effect of a change in accounting principle,
net of tax (Note 2) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
—
—
(22.0)
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 2,953.0
$ 2,662.7
$ 1,979.6
Earnings per share—basic (Note 10)
Income before cumulative effect of a change in accounting
principle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cumulative effect of a change in accounting principle . . . . . . . . . .
Net income. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Earnings per share—diluted (Note 10)
Income before cumulative effect of a change in accounting
principle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cumulative effect of a change in accounting principle . . . . . . . . . .
Net income. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
See notes to consolidated fi nancial statements.
$2.71
—
$2.71
$2.71
—
$2.71
$2.45
—
$2.45
$2.45
—
$2.45
$1.84
(0.02)
$1.82
$1.83
(0.02)
$1.81
14
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treatment of type 2 diabetes, a portion of which rep-
resent revenues from a copromotion agreement in
the U.S. with Takeda Pharmaceuticals North America
(Takeda), decreased 46 percent in the U.S. Actos is
manufactured by Takeda Chemical Industries, Ltd.,
and sold in the U.S. by Takeda. Our U.S. marketing
rights with respect to Actos expired in September 2006;
however, we continue to receive royalties from Takeda
through September 2009 at rates that decline each year.
Our arrangement outside the U.S. continues. Sales out-
side the U.S. increased 30 percent, driven primarily by
increased demand and to a lesser extent, the favorable
impact of foreign exchange rates.
Worldwide sales of Byetta, an injectable product for
the treatment of type 2 diabetes, which we market with
Amylin Pharmaceuticals (Amylin), increased 51 percent
to $650.2 million during 2007. We report as revenue
our 50 percent share of Byetta’s gross margin in the
U.S., 100 percent of Byetta sales outside the U.S., and
our sales of Byetta pen delivery devices to Amylin. Our
revenues increased 51 percent to $330.7 million in 2007.
Animal health product sales in the U.S. increased
18 percent, driven by increased demand, the acquisi-
tion of Ivy Animal Health, and new companion-animal
product launches. Sales outside the U.S. increased
10 percent, driven by the favorable impact of foreign
exchange rates and increased demand.
Gross Margin, Costs, and Expenses
The 2007 gross margin decreased to 77.2 percent of
sales compared with 77.4 percent for 2006. This de-
crease was primarily due to the expense resulting from
the amortization of the intangible assets acquired in
the ICOS acquisition, the unfavorable impact of foreign
exchange rates, and production volumes growing at a
slower rate than sales, offset partially by manufactur-
ing expenses growing at a slower rate than sales.
Operating expenses (the aggregate of research and
development and marketing, selling, and administra-
tive expenses) increased 19 percent in 2007. Investment
in research and development increased 11 percent, to
$3.49 billion. In addition to the acquisition of ICOS, this
increase was due to increases in discovery research
and late-stage clinical trial costs. We continued to be a
leader in our industry peer group by investing approxi-
mately 19 percent of our sales into research and devel-
opment during 2007. Marketing, selling, and adminis-
trative expenses increased 25 percent in 2007, to $6.10
billion. This increase was largely due to the impact
of the ICOS acquisition, as well as increased market-
ing and selling expenses in support of key products,
primarily Cymbalta and the diabetes care products, and
the unfavorable impact of foreign exchange rates.
Acquired IPR&D charges were $745.6 million in
2007 and related to the acquisitions of ICOS, Hypnion,
and Ivy, as well as our licensing arrangements with OSI,
(cid:26)
(cid:44)
(cid:35)
(cid:45)
(cid:44)
(cid:26)
(cid:44)
(cid:35)
(cid:43)
(cid:44)
(cid:26)
(cid:40)
(cid:35)
(cid:43)
(cid:44)
(cid:26)
(cid:41)
(cid:35)
(cid:44)
(cid:44)
(cid:26)
(cid:39)
(cid:35)
(cid:44)
(cid:44)
(cid:60)(cid:103)(cid:100)(cid:104)(cid:104)(cid:21)(cid:66)(cid:86)(cid:103)(cid:92)(cid:94)(cid:99)
(cid:29)(cid:101)(cid:90)(cid:103)(cid:88)(cid:90)(cid:99)(cid:105)(cid:21)(cid:100)(cid:91)(cid:21)(cid:99)(cid:90)(cid:105)(cid:21)(cid:104)(cid:86)(cid:97)(cid:90)(cid:104)(cid:30)(cid:21)
(cid:20)(cid:192)(cid:156)(cid:196)(cid:196)(cid:202)(cid:148)(cid:58)(cid:192)(cid:122)(cid:134)(cid:151)(cid:202)(cid:58)(cid:196)(cid:202)(cid:58)(cid:202)(cid:168)(cid:103)(cid:192)(cid:83)(cid:103)(cid:151)(cid:205)(cid:202)(cid:156)(cid:115)(cid:202)(cid:151)(cid:103)(cid:205)(cid:202)(cid:196)(cid:58)(cid:143)(cid:103)(cid:196)(cid:202)(cid:94)(cid:103)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:94)(cid:202)
(cid:196)(cid:143)(cid:134)(cid:122)(cid:131)(cid:205)(cid:143)(cid:219)(cid:202)(cid:134)(cid:151)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:91)(cid:202)(cid:94)(cid:210)(cid:103)(cid:202)(cid:168)(cid:192)(cid:134)(cid:148)(cid:58)(cid:192)(cid:134)(cid:143)(cid:219)(cid:202)(cid:205)(cid:156)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:103)(cid:218)(cid:168)(cid:103)(cid:151)(cid:196)(cid:103)(cid:202)
(cid:192)(cid:103)(cid:196)(cid:210)(cid:143)(cid:205)(cid:134)(cid:151)(cid:122)(cid:202)(cid:115)(cid:192)(cid:156)(cid:148)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:58)(cid:148)(cid:156)(cid:192)(cid:205)(cid:134)(cid:222)(cid:58)(cid:205)(cid:134)(cid:156)(cid:151)(cid:202)(cid:156)(cid:115)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:134)(cid:151)(cid:205)(cid:58)(cid:151)(cid:122)(cid:134)(cid:74)(cid:143)(cid:103)(cid:202)
(cid:58)(cid:196)(cid:196)(cid:103)(cid:205)(cid:196)(cid:202)(cid:58)(cid:83)(cid:181)(cid:210)(cid:134)(cid:192)(cid:103)(cid:94)(cid:202)(cid:134)(cid:151)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:22)(cid:10)(cid:33)(cid:45)(cid:202)(cid:58)(cid:83)(cid:181)(cid:210)(cid:134)(cid:196)(cid:134)(cid:205)(cid:134)(cid:156)(cid:151)(cid:91)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)
(cid:210)(cid:151)(cid:115)(cid:58)(cid:216)(cid:156)(cid:192)(cid:58)(cid:74)(cid:143)(cid:103)(cid:202)(cid:134)(cid:148)(cid:168)(cid:58)(cid:83)(cid:205)(cid:202)(cid:156)(cid:115)(cid:202)(cid:115)(cid:156)(cid:192)(cid:103)(cid:134)(cid:122)(cid:151)(cid:202)(cid:103)(cid:218)(cid:83)(cid:131)(cid:58)(cid:151)(cid:122)(cid:103)(cid:202)(cid:192)(cid:58)(cid:205)(cid:103)(cid:196)(cid:91)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)
(cid:168)(cid:192)(cid:156)(cid:94)(cid:210)(cid:83)(cid:205)(cid:134)(cid:156)(cid:151)(cid:202)(cid:216)(cid:156)(cid:143)(cid:210)(cid:148)(cid:103)(cid:196)(cid:202)(cid:122)(cid:192)(cid:156)(cid:217)(cid:134)(cid:151)(cid:122)(cid:202)(cid:58)(cid:205)(cid:202)(cid:58)(cid:202)(cid:196)(cid:143)(cid:156)(cid:217)(cid:103)(cid:192)(cid:202)(cid:192)(cid:58)(cid:205)(cid:103)(cid:202)(cid:205)(cid:131)(cid:58)(cid:151)(cid:202)
(cid:196)(cid:58)(cid:143)(cid:103)(cid:196)(cid:91)(cid:202)(cid:156)(cid:115)(cid:115)(cid:196)(cid:103)(cid:205)(cid:202)(cid:168)(cid:58)(cid:192)(cid:205)(cid:134)(cid:58)(cid:143)(cid:143)(cid:219)(cid:202)(cid:74)(cid:219)(cid:202)(cid:148)(cid:58)(cid:151)(cid:210)(cid:115)(cid:58)(cid:83)(cid:205)(cid:210)(cid:192)(cid:134)(cid:151)(cid:122)(cid:202)(cid:103)(cid:218)(cid:168)(cid:103)(cid:151)(cid:196)(cid:103)(cid:196)(cid:202)
(cid:122)(cid:192)(cid:156)(cid:217)(cid:134)(cid:151)(cid:122)(cid:202)(cid:58)(cid:205)(cid:202)(cid:58)(cid:202)(cid:196)(cid:143)(cid:156)(cid:217)(cid:103)(cid:192)(cid:202)(cid:192)(cid:58)(cid:205)(cid:103)(cid:202)(cid:205)(cid:131)(cid:58)(cid:151)(cid:202)(cid:196)(cid:58)(cid:143)(cid:103)(cid:196)(cid:174)(cid:202)(cid:202)
(cid:21) (cid:37)(cid:40)(cid:21) (cid:37)(cid:41)(cid:21) (cid:37)(cid:42)(cid:21) (cid:37)(cid:43)(cid:21) (cid:37)(cid:44)
MacroGenics, and Glenmark. We incurred asset impair-
ments, restructuring, and other special charges of
$302.5 million in 2007 as compared to $945.2 million in
2006. See Notes 3, 4 and 13 to the consolidated fi nancial
statements for additional information.
Other income—net decreased $115.8 million, to
$122.0 million. This line item consists of interest ex-
pense, interest income, the after-tax operating results
of the Lilly ICOS joint venture, and all other miscella-
neous income and expense items.
• Interest expense for 2007 decreased $9.8 million,
to $228.3 million. This decrease is a result of lower
average debt balances in 2007 compared to 2006.
• Interest income for 2007 decreased $46.6 million, to
$215.3 million, due to lower cash balances in 2007
compared to 2006.
• The Lilly ICOS joint-venture income was $11.0 million
in 2007 as compared to $96.3 million in 2006, due to
the acquisition of ICOS on January 29, 2007.
• Net other miscellaneous income items increased
$6.3 million to $124.0 million.
We incurred tax expense of $923.8 million in
2007, resulting in an effective tax rate of 23.8 percent,
compared with 22.1 percent for 2006. The effective tax
(cid:71)(cid:90)(cid:104)(cid:90)(cid:86)(cid:103)(cid:88)(cid:93)(cid:21)(cid:86)(cid:99)(cid:89)(cid:21)(cid:57)(cid:90)(cid:107)(cid:90)(cid:97)(cid:100)(cid:101)(cid:98)(cid:90)(cid:99)(cid:105)(cid:21)(cid:62)(cid:99)(cid:107)(cid:90)(cid:104)(cid:105)(cid:98)(cid:90)(cid:99)(cid:105)(cid:21)
(cid:62)(cid:99)(cid:88)(cid:103)(cid:90)(cid:86)(cid:104)(cid:94)(cid:99)(cid:92)
(cid:29)(cid:25)(cid:21)(cid:98)(cid:94)(cid:97)(cid:97)(cid:94)(cid:100)(cid:99)(cid:104)(cid:33)(cid:21)(cid:101)(cid:90)(cid:103)(cid:88)(cid:90)(cid:99)(cid:105)(cid:21)(cid:100)(cid:91)(cid:21)(cid:99)(cid:90)(cid:105)(cid:21)(cid:104)(cid:86)(cid:97)(cid:90)(cid:104)(cid:30)(cid:21)
(cid:44)(cid:103)(cid:196)(cid:103)(cid:58)(cid:192)(cid:83)(cid:131)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:94)(cid:103)(cid:216)(cid:103)(cid:143)(cid:156)(cid:168)(cid:148)(cid:103)(cid:151)(cid:205)(cid:202)(cid:103)(cid:218)(cid:168)(cid:103)(cid:151)(cid:94)(cid:134)(cid:205)(cid:210)(cid:192)(cid:103)(cid:196)(cid:202)
(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:94)(cid:202)(cid:74)(cid:219)(cid:202)(cid:163)(cid:163)(cid:202)(cid:168)(cid:103)(cid:192)(cid:83)(cid:103)(cid:151)(cid:205)(cid:91)(cid:202)(cid:205)(cid:156)(cid:202)(cid:100)(cid:206)(cid:174)(cid:117)(cid:202)(cid:74)(cid:134)(cid:143)(cid:143)(cid:134)(cid:156)(cid:151)(cid:91)(cid:202)(cid:134)(cid:151)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:202)
(cid:94)(cid:210)(cid:103)(cid:202)(cid:205)(cid:156)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:196)(cid:202)(cid:134)(cid:151)(cid:202)(cid:94)(cid:134)(cid:196)(cid:83)(cid:156)(cid:216)(cid:103)(cid:192)(cid:219)(cid:202)(cid:192)(cid:103)(cid:196)(cid:103)(cid:58)(cid:192)(cid:83)(cid:131)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)
(cid:143)(cid:58)(cid:205)(cid:103)(cid:133)(cid:196)(cid:205)(cid:58)(cid:122)(cid:103)(cid:202)(cid:83)(cid:143)(cid:134)(cid:151)(cid:134)(cid:83)(cid:58)(cid:143)(cid:202)(cid:205)(cid:192)(cid:134)(cid:58)(cid:143)(cid:202)(cid:83)(cid:156)(cid:196)(cid:205)(cid:196)(cid:174)(cid:202)(cid:46)(cid:131)(cid:134)(cid:196)(cid:202)(cid:196)(cid:210)(cid:196)(cid:205)(cid:58)(cid:134)(cid:151)(cid:103)(cid:94)(cid:202)(cid:143)(cid:103)(cid:216)(cid:103)(cid:143)(cid:202)
(cid:156)(cid:115)(cid:202)(cid:134)(cid:151)(cid:216)(cid:103)(cid:196)(cid:205)(cid:148)(cid:103)(cid:151)(cid:205)(cid:202)(cid:134)(cid:151)(cid:202)(cid:192)(cid:103)(cid:196)(cid:103)(cid:58)(cid:192)(cid:83)(cid:131)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:94)(cid:103)(cid:216)(cid:103)(cid:143)(cid:156)(cid:168)(cid:148)(cid:103)(cid:151)(cid:205)(cid:202)
(cid:103)(cid:151)(cid:58)(cid:74)(cid:143)(cid:103)(cid:94)(cid:202)(cid:210)(cid:196)(cid:202)(cid:205)(cid:156)(cid:202)(cid:148)(cid:156)(cid:216)(cid:103)(cid:202)(cid:58)(cid:151)(cid:202)(cid:210)(cid:151)(cid:168)(cid:192)(cid:103)(cid:83)(cid:103)(cid:94)(cid:103)(cid:151)(cid:205)(cid:103)(cid:94)(cid:202)(cid:151)(cid:210)(cid:148)(cid:74)(cid:103)(cid:192)(cid:202)
(cid:156)(cid:115)(cid:202)(cid:94)(cid:192)(cid:210)(cid:122)(cid:202)(cid:83)(cid:58)(cid:151)(cid:94)(cid:134)(cid:94)(cid:58)(cid:205)(cid:103)(cid:196)(cid:202)(cid:134)(cid:151)(cid:205)(cid:156)(cid:202)(cid:131)(cid:210)(cid:148)(cid:58)(cid:151)(cid:202)(cid:83)(cid:143)(cid:134)(cid:151)(cid:134)(cid:83)(cid:58)(cid:143)(cid:202)(cid:205)(cid:192)(cid:134)(cid:58)(cid:143)(cid:196)(cid:202)(cid:134)(cid:151)(cid:202)
(cid:209)(cid:223)(cid:223)(cid:199)(cid:91)(cid:202)(cid:196)(cid:210)(cid:168)(cid:168)(cid:156)(cid:192)(cid:205)(cid:134)(cid:151)(cid:122)(cid:202)(cid:156)(cid:210)(cid:192)(cid:202)(cid:83)(cid:156)(cid:148)(cid:148)(cid:134)(cid:205)(cid:148)(cid:103)(cid:151)(cid:205)(cid:202)(cid:205)(cid:156)(cid:202)(cid:94)(cid:103)(cid:216)(cid:103)(cid:143)(cid:156)(cid:168)(cid:202)
(cid:74)(cid:103)(cid:196)(cid:205)(cid:133)(cid:134)(cid:151)(cid:133)(cid:83)(cid:143)(cid:58)(cid:196)(cid:196)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:115)(cid:134)(cid:192)(cid:196)(cid:205)(cid:133)(cid:134)(cid:151)(cid:133)(cid:83)(cid:143)(cid:58)(cid:196)(cid:196)(cid:202)(cid:148)(cid:103)(cid:94)(cid:134)(cid:83)(cid:134)(cid:151)(cid:103)(cid:196)(cid:202)(cid:205)(cid:156)(cid:202)
(cid:168)(cid:192)(cid:156)(cid:216)(cid:134)(cid:94)(cid:103)(cid:202)(cid:58)(cid:151)(cid:196)(cid:217)(cid:103)(cid:192)(cid:196)(cid:202)(cid:115)(cid:156)(cid:192)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:210)(cid:151)(cid:148)(cid:103)(cid:205)(cid:202)(cid:148)(cid:103)(cid:94)(cid:134)(cid:83)(cid:58)(cid:143)(cid:202)(cid:151)(cid:103)(cid:103)(cid:94)(cid:196)(cid:202)
(cid:156)(cid:115)(cid:202)(cid:156)(cid:210)(cid:192)(cid:202)(cid:83)(cid:210)(cid:196)(cid:205)(cid:156)(cid:148)(cid:103)(cid:192)(cid:196)(cid:174)(cid:202)(cid:202)
(cid:26)
(cid:44)
(cid:35)
(cid:45)
(cid:38)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:44)
(cid:45)
(cid:41)
(cid:33)
(cid:40)
(cid:25)
(cid:26)
(cid:46)
(cid:35)
(cid:46)
(cid:38)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:46)
(cid:39)
(cid:38)
(cid:33)
(cid:40)
(cid:25)
(cid:26)
(cid:44)
(cid:35)
(cid:37)
(cid:39)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:43)
(cid:39)
(cid:37)
(cid:33)
(cid:40)
(cid:25)
(cid:26)
(cid:41)
(cid:35)
(cid:46)
(cid:38)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:38)
(cid:46)
(cid:43)
(cid:33)
(cid:39)
(cid:25)
(cid:26)
(cid:44)
(cid:35)
(cid:45)
(cid:38)
(cid:21)
(cid:21)
(cid:21)
(cid:21)
(cid:37)
(cid:42)
(cid:40)
(cid:33)
(cid:39)
(cid:25)
(cid:21) (cid:37)(cid:40)(cid:21) (cid:37)(cid:41)(cid:21) (cid:37)(cid:42)(cid:21) (cid:37)(cid:43)(cid:21) (cid:37)(cid:44)
15
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rates for 2007 and 2006 were affected primarily by the
nondeductible ICOS and Hypnion IPR&D charges of
$594.6 million in 2007, and the product liability charges
of $494.9 million in 2006. The tax effect of the product
liability charge was less than our effective tax rate, as
the tax benefi t was calculated based upon existing tax
laws in the countries in which we reasonably expect
to deduct the charge. See Note 11 to the consolidated
fi nancial statements for additional information.
OPERATING RESULTS—2006
Financial Results
We achieved worldwide sales growth of 7 percent,
primarily as a result of strong growth of our newer
products. We increased our investment in market-
ing expenses in support of key products, primarily
Cymbalta and the diabetes care products, and contin-
ued our commitment to research and development,
investing approximately 20 percent of our sales during
2006. Our results also benefi ted from continued growth
in profi tability of the Lilly ICOS joint venture as well
as cost-containment and productivity initiatives. Net
income was $2.66 billion, or $2.45 per share, in 2006 as
compared with $1.98 billion, or $1.81 per share, in 2005,
representing an increase in net income and earnings
per share of 35 percent. Certain items, refl ected in our
operating results for 2006 and 2005, should be consid-
ered in comparing the two years. The signifi cant items
for 2006 are summarized in the Executive Overview.
The 2005 items are summarized as follows (see Notes
2, 4, and 13 to the consolidated fi nancial statements for
additional information):
• We incurred a charge related to product liability
litigation matters, primarily related to Zyprexa, of
$1.07 billion (pretax), which decreased earnings per
share by $.90 in the second quarter (Notes 4 and 13).
• We recognized asset impairments and other special
charges of $171.9 million (pretax) in the fourth quarter,
which decreased earnings per share by $.14 (Note 4).
• We adopted Financial Accounting Standards
Board (FASB) Interpretation (FIN) 47, Accounting
for Conditional Asset Retirement Obligations, an
interpretation of FASB Statement No. 143, in the
fourth quarter. The adoption of FIN 47 resulted in an
adjustment for the cumulative effect of a change in
accounting principle of $22.0 million (after-tax), which
decreased earnings per share by $.02 (Note 2).
Sales
Our worldwide sales for 2006 increased 7 percent,
to $15.69 billion, driven primarily by sales growth of
Cymbalta, Forteo, Byetta, Zyprexa, and Alimta. World-
wide sales volume increased 3 percent, and selling
prices increased sales by 4 percent. Foreign exchange
rates did not impact our overall sales growth. Sales in
16
the U.S. increased 10 percent, to $8.60 billion, driven
primarily by increased sales of Cymbalta, diabetes
care products, Forteo, and Zyprexa. U.S. growth com-
parisons benefi ted from an estimated $170 million of
wholesaler destocking that had occurred in 2005 as a
result of restructuring our arrangements with our U.S.
wholesalers in the fi rst quarter of 2005. Additionally,
we experienced a sales benefi t resulting from a shift of
certain low-income patients from Medicaid to Medicare
and increased access to medical coverage by certain
patients previously covered under our LillyAnswers®
program following the implementation of MMA in 2006.
This contributed part of the increases in U.S. net ef-
fective sales prices of 9 percent. Sales outside the U.S.
increased 4 percent, to $7.09 billion, driven by growth of
Cymbalta, Alimta, and Zyprexa.
Zyprexa sales in the U.S. increased 4 percent in
2006, driven by higher prices, offset in part by lower
demand. The increase in net selling prices was partially
due to the transition of certain low-income patients
from Medicaid to Medicare. Sales outside the U.S.
increased 4 percent, driven primarily by increased de-
mand, offset in part by declining prices.
Diabetes care products had aggregate worldwide
revenues of $2.96 billion in 2006, an increase of 6 per-
cent. Diabetes care revenues in the U.S. increased 8 per-
cent, to $1.73 billion. Diabetes care revenues outside the
U.S. increased 2 percent, to $1.23 billion. Results from
our primary diabetes care products are as follows:
• Humalog sales increased 10 percent in the U.S., due
primarily to higher prices, and increased 7 percent
outside the U.S., due primarily to increased volume,
offset partially by lower prices.
• Humulin sales in the U.S. decreased 10 percent due
primarily to decreased volume, offset partially by
increased selling prices. Outside the U.S., Humulin
sales decreased 6 percent due to decreases in demand
and selling prices.
• Actos revenues in the U.S. decreased 22 percent in
2006, due to the expiration of our U.S. marketing rights
in September 2006. Sales outside the U.S. increased
23 percent, due primarily to increased volume in
addition to a favorable impact of foreign exchange
rates, offset in part by lower prices.
• Total sales of Byetta, launched in the U.S. in June 2005,
were $430.2 million for 2006.
Sales of Gemzar increased 4 percent in the U.S.,
due primarily to higher prices as well as the reductions
in U.S. wholesaler inventory levels in 2005. Gemzar
sales increased 7 percent outside the U.S., driven by
strong volume.
Sales of Cymbalta increased 82 percent in the U.S.,
due to strong demand. Sales of Cymbalta outside the
U.S. refl ect international launches.
Sales of Evista increased 2 percent in the U.S. due
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The following table summarizes our net sales activity in 2006 compared with 2005:
Product
(Dollars in millions)
Zyprexa . . . . . . . . . . . . . . . . . . . . . .
Gemzar . . . . . . . . . . . . . . . . . . . . . .
Cymbalta. . . . . . . . . . . . . . . . . . . . .
Humalog . . . . . . . . . . . . . . . . . . . . .
Evista . . . . . . . . . . . . . . . . . . . . . . . .
Humulin. . . . . . . . . . . . . . . . . . . . . .
Animal health products. . . . . . . . .
Alimta . . . . . . . . . . . . . . . . . . . . . . .
Forteo . . . . . . . . . . . . . . . . . . . . . . .
Strattera . . . . . . . . . . . . . . . . . . . . .
Actos . . . . . . . . . . . . . . . . . . . . . . . .
Humatrope . . . . . . . . . . . . . . . . . . .
Byetta . . . . . . . . . . . . . . . . . . . . . . .
Cialis2 . . . . . . . . . . . . . . . . . . . . . . .
Other pharmaceutical products . .
Total net sales . . . . . . . . . . . . . .
U.S.1
$ 2,106.2
609.8
1,158.7
811.0
664.0
367.9
405.9
350.1
416.2
509.2
279.1
202.3
219.0
3.7
496.1
$8,599.2
Year Ended
December 31, 2006
Outside U.S.
$2,257.4
798.3
157.7
488.5
381.3
557.4
469.6
261.7
178.1
69.8
169.4
213.3
—
212.1
877.2
$7,091.8
Total
$ 4,363.6
1,408.1
1,316.4
1,299.5
1,045.3
925.3
875.5
611.8
594.3
579.0
448.5
415.6
219.0
215.8
1,373.3
$15,691.0
Year Ended
December 31, 2005
Total
Percent
Change
from 2005
$ 4,202.3
1,334.5
679.7
1,197.7
1,036.1
1,004.7
863.7
463.2
389.3
552.1
493.0
414.4
39.6
169.9
1,805.1
$14,645.3
4
6
94
9
1
(8)
1
32
53
5
(9)
0
NM
27
(24)
7
NM—Not meaningful
1U.S. sales include sales in Puerto Rico.
2Cialis had worldwide 2006 sales of $971.0 million, representing an increase of 30 percent compared with 2005. The sales shown in
the table above represent results only in the territories in which we marketed Cialis exclusively. The remaining sales relate to the
joint-venture territories of Lilly ICOS LLC (North America, excluding Puerto Rico, and Europe). Our share of the joint-venture territory
sales, net of expenses and income taxes, is reported in other income—net in our consolidated statements of income.
to higher prices, offset partially by a decline in demand.
Outside the U.S., sales of Evista decreased 1 percent,
driven by lower prices, offset by an increase in demand.
Sales of Alimta increased 18 percent and 57 percent
creased 5 percent, driven primarily by the decrease
in the sales of Surmax® as a result of the European
Union’s growth promotion use ban on the product,
effective January 1, 2006.
in the U.S. and outside the U.S., respectively, due pri-
marily to increased demand.
Sales of Forteo increased 57 percent in the U.S. In
addition to increased demand, U.S. sales signifi cantly
benefi ted from patients’ access to medical coverage
through the Medicare Part D program and from de-
creased utilization of our U.S. patient assistance pro-
gram, LillyAnswers. Sales outside the U.S. increased
43 percent, refl ecting strong demand.
Sales of Strattera increased 2 percent in the U.S.
due to higher prices as well as the reductions in U.S.
wholesaler inventory levels in 2005, offset by a decline
in demand. Sales outside the U.S. increased 31 percent
due primarily to increased demand in addition to a mod-
est favorable impact of foreign exchange rates, offset
partially by lower prices.
Total product sales of Cialis increased 38 percent
in the U.S. and 24 percent outside the U.S. Worldwide
Cialis sales growth refl ects the impact of market share
gains, market growth, and price increases during 2006.
Animal health product sales in the U.S. increased
10 percent, due primarily to increased demand led
by Rumensin® and Tylan®. Sales outside the U.S. de-
Gross Margin, Costs, and Expenses
The 2006 gross margin increased to 77.4 percent of
sales compared with 76.3 percent for 2005. This in-
crease was primarily due to increased product prices
and increased production volume, partially offset by
higher manufacturing expenses.
Operating expenses increased 7 percent in 2006.
Investment in research and development increased
3 percent, to $3.13 billion, primarily due to increases in
discovery research and clinical trial costs. We contin-
ued to be a leader in our industry peer group by invest-
ing approximately 20 percent of our sales into research
and development during 2006. Marketing, selling, and
administrative expenses increased 9 percent in 2006, to
$4.89 billion. This increase was largely attributable to
increased marketing and selling expenses in support of
key products, primarily Cymbalta and the diabetes care
franchise, and an increase in litigation-related costs.
Other income—net decreased $76.4 million, to
$237.8 million.
• Interest expense for 2006 increased $132.9 million,
to $238.1 million. This increase was a result of higher
17
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interest rates and less capitalized interest due to
the completion in late 2005 of certain manufacturing
facilities.
• Interest income for 2006 increased $49.8 million, to
$261.9 million, due to higher short-term interest rates.
• The Lilly ICOS joint-venture income was $96.3 mil-
lion in 2006 as compared to $11.1 million in 2005.
The increase was due to increased Cialis sales and
decreased selling and marketing expenses.
• Net other miscellaneous income items decreased
$78.5 million, to $117.7 million, primarily as a result
of less income related to the outlicensing of legacy
products and partnered compounds in development.
We incurred tax expense of $755.3 million in 2006,
resulting in an effective tax rate of 22.1 percent, com-
pared with 26.3 percent for 2005. The effective tax
rates for 2006 and 2005 were affected primarily by the
product liability charges of $494.9 million and $1.07 bil-
lion, respectively. The tax benefi t associated with these
charges was less than our effective tax rate, as the tax
benefi t was calculated based upon existing tax laws in
the countries in which we reasonably expect to deduct
the charge. See Note 11 to the consolidated fi nancial
statements for additional information.
FINANCIAL CONDITION
As of December 31, 2007, cash, cash equivalents, and
short-term investments totaled $4.83 billion compared
with $3.89 billion at December 31, 2006. Cash fl ow from
operations in 2007 of $5.15 billion and net proceeds from
the issuance of long-term debt of $1.45 billion exceeded
the total of the net cash paid for corporate acquisitions
of $2.67 billion, dividends paid of $1.85 billion, and pur-
chases of property and equipment of $1.08 billion.
Capital expenditures of $1.08 billion during 2007
were consistent with 2006, due primarily to the man-
agement of capital spending. We expect near-term
capital expenditures to remain approximately the same
as 2007 levels while we invest in our biotech and re-
search and development initiatives, continue to upgrade
our manufacturing facilities to enhance productivity and
quality systems, and invest in the long-term growth of
our diabetes care products.
Total debt as of December 31, 2007 increased $1.29
billion, to $5.01 billion, refl ecting the $2.50 billion of
debt we issued in 2007 to fi nance our acquisition of
ICOS, offset by long-term debt repayment of $1.06 bil-
lion. Our current debt ratings from Standard & Poor’s
and Moody’s remain at AA and Aa3, respectively.
Dividends of $1.70 per share were paid in 2007, an
increase of 6 percent from 2006. In the fourth quarter of
2007, effective for the fi rst-quarter dividend in 2008, the
quarterly dividend was increased to $.47 per share (a
10.6 percent increase), resulting in an indicated annual
18
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(cid:148)(cid:58)(cid:151)(cid:210)(cid:115)(cid:58)(cid:83)(cid:205)(cid:210)(cid:192)(cid:134)(cid:151)(cid:122)(cid:202)(cid:115)(cid:58)(cid:83)(cid:134)(cid:143)(cid:134)(cid:205)(cid:134)(cid:103)(cid:196)(cid:202)(cid:205)(cid:156)(cid:202)(cid:103)(cid:151)(cid:131)(cid:58)(cid:151)(cid:83)(cid:103)(cid:202)(cid:168)(cid:192)(cid:156)(cid:94)(cid:210)(cid:83)(cid:205)(cid:134)(cid:216)(cid:134)(cid:205)(cid:219)(cid:202)
(cid:58)(cid:151)(cid:94)(cid:202)(cid:181)(cid:210)(cid:58)(cid:143)(cid:134)(cid:205)(cid:219)(cid:202)(cid:196)(cid:219)(cid:196)(cid:205)(cid:103)(cid:148)(cid:196)(cid:91)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:134)(cid:151)(cid:216)(cid:103)(cid:196)(cid:205)(cid:202)(cid:134)(cid:151)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:143)(cid:156)(cid:151)(cid:122)(cid:133)(cid:205)(cid:103)(cid:192)(cid:148)(cid:202)
(cid:122)(cid:192)(cid:156)(cid:217)(cid:205)(cid:131)(cid:202)(cid:156)(cid:115)(cid:202)(cid:156)(cid:210)(cid:192)(cid:202)(cid:94)(cid:134)(cid:58)(cid:74)(cid:103)(cid:205)(cid:103)(cid:196)(cid:202)(cid:83)(cid:58)(cid:192)(cid:103)(cid:202)(cid:168)(cid:192)(cid:156)(cid:94)(cid:210)(cid:83)(cid:205)(cid:196)(cid:174)(cid:202)(cid:202)
(cid:45)
(cid:46)
(cid:45)
(cid:33)
(cid:38)
(cid:25)
(cid:44)
(cid:37)
(cid:44)
(cid:33)
(cid:38)
(cid:25)
(cid:45)
(cid:46)
(cid:39)
(cid:33)
(cid:38)
(cid:25)
(cid:45)
(cid:44)
(cid:37)
(cid:33)
(cid:38)
(cid:25)
(cid:39)
(cid:45)
(cid:37)
(cid:33)
(cid:38)
(cid:25)
(cid:21) (cid:37)(cid:40)(cid:21) (cid:37)(cid:41)(cid:21) (cid:37)(cid:42)(cid:21) (cid:37)(cid:43)(cid:21) (cid:37)(cid:44)
rate for 2008 of $1.88 per share. The year 2007 was the
123rd consecutive year in which we made dividend pay-
ments and the 40th consecutive year in which dividends
have been increased.
We believe that cash generated from operations,
along with available cash and cash equivalents, will be
suffi cient to fund our normal operating needs, includ-
ing debt service, capital expenditures, costs associated
with product liability litigation, dividends, and taxes in
2008. We believe that amounts accessible through ex-
isting commercial paper markets should be adequate to
fund short-term borrowings, if necessary. We currently
have $1.24 billion of unused committed bank credit
facilities, $1.20 billion of which backs our commercial
paper program. Our access to credit markets has not
been adversely affected by the recent illiquidity in the
market. Various risks and uncertainties, including those
discussed in the Financial Expectations for 2008 section,
may affect our operating results and cash generated
from operations.
In the normal course of business, our operations
are exposed to fl uctuations in interest rates and cur-
rency values. These fl uctuations can vary the costs
of fi nancing, investing, and operating. We address a
(cid:57)(cid:94)(cid:107)(cid:94)(cid:89)(cid:90)(cid:99)(cid:89)(cid:104)(cid:21)(cid:69)(cid:86)(cid:94)(cid:89)(cid:21)(cid:69)(cid:90)(cid:103)(cid:21)(cid:72)(cid:93)(cid:86)(cid:103)(cid:90)(cid:21)(cid:56)(cid:100)(cid:99)(cid:105)(cid:94)(cid:99)(cid:106)(cid:90)(cid:21)(cid:105)(cid:100)(cid:21)(cid:60)(cid:103)(cid:100)(cid:108)
(cid:29)(cid:25)(cid:21)(cid:89)(cid:100)(cid:97)(cid:97)(cid:86)(cid:103)(cid:104)(cid:30)(cid:21)
(cid:12)(cid:134)(cid:216)(cid:134)(cid:94)(cid:103)(cid:151)(cid:94)(cid:196)(cid:202)(cid:168)(cid:58)(cid:134)(cid:94)(cid:202)(cid:94)(cid:210)(cid:192)(cid:134)(cid:151)(cid:122)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:94)(cid:202)(cid:205)(cid:156)(cid:202)(cid:100)(cid:163)(cid:174)(cid:199)(cid:223)(cid:202)
(cid:168)(cid:103)(cid:192)(cid:202)(cid:196)(cid:131)(cid:58)(cid:192)(cid:103)(cid:174)(cid:202)(cid:46)(cid:131)(cid:134)(cid:196)(cid:202)(cid:83)(cid:156)(cid:151)(cid:196)(cid:205)(cid:134)(cid:205)(cid:210)(cid:205)(cid:103)(cid:196)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:120)(cid:223)(cid:205)(cid:131)(cid:202)(cid:83)(cid:156)(cid:151)(cid:196)(cid:103)(cid:83)(cid:210)(cid:205)(cid:134)(cid:216)(cid:103)(cid:202)
(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:202)(cid:134)(cid:151)(cid:202)(cid:58)(cid:151)(cid:151)(cid:210)(cid:58)(cid:143)(cid:202)(cid:94)(cid:134)(cid:216)(cid:134)(cid:94)(cid:103)(cid:151)(cid:94)(cid:196)(cid:174)(cid:202)(cid:33)(cid:210)(cid:192)(cid:202)(cid:196)(cid:205)(cid:192)(cid:156)(cid:151)(cid:122)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:202)
(cid:192)(cid:103)(cid:196)(cid:210)(cid:143)(cid:205)(cid:196)(cid:202)(cid:103)(cid:151)(cid:58)(cid:74)(cid:143)(cid:103)(cid:94)(cid:202)(cid:210)(cid:196)(cid:202)(cid:205)(cid:156)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:115)(cid:134)(cid:192)(cid:196)(cid:205)(cid:133)(cid:181)(cid:210)(cid:58)(cid:192)(cid:205)(cid:103)(cid:192)(cid:202)
(cid:209)(cid:223)(cid:223)(cid:108)(cid:202)(cid:94)(cid:134)(cid:216)(cid:134)(cid:94)(cid:103)(cid:151)(cid:94)(cid:202)(cid:74)(cid:219)(cid:202)(cid:163)(cid:223)(cid:174)(cid:200)(cid:202)(cid:168)(cid:103)(cid:192)(cid:83)(cid:103)(cid:151)(cid:205)(cid:91)(cid:202)(cid:205)(cid:156)(cid:202)(cid:100)(cid:174)(cid:120)(cid:199)(cid:202)(cid:168)(cid:103)(cid:192)(cid:202)(cid:196)(cid:131)(cid:58)(cid:192)(cid:103)(cid:174)(cid:202)
(cid:46)(cid:131)(cid:134)(cid:196)(cid:202)(cid:196)(cid:210)(cid:74)(cid:196)(cid:205)(cid:58)(cid:151)(cid:205)(cid:134)(cid:58)(cid:143)(cid:202)(cid:134)(cid:151)(cid:83)(cid:192)(cid:103)(cid:58)(cid:196)(cid:103)(cid:202)(cid:192)(cid:103)(cid:115)(cid:143)(cid:103)(cid:83)(cid:205)(cid:196)(cid:202)(cid:156)(cid:210)(cid:192)(cid:202)(cid:83)(cid:156)(cid:151)(cid:205)(cid:134)(cid:151)(cid:210)(cid:103)(cid:94)(cid:202)
(cid:83)(cid:156)(cid:148)(cid:148)(cid:134)(cid:205)(cid:148)(cid:103)(cid:151)(cid:205)(cid:202)(cid:205)(cid:156)(cid:202)(cid:103)(cid:151)(cid:131)(cid:58)(cid:151)(cid:83)(cid:134)(cid:151)(cid:122)(cid:202)(cid:196)(cid:131)(cid:58)(cid:192)(cid:103)(cid:131)(cid:156)(cid:143)(cid:94)(cid:103)(cid:192)(cid:202)(cid:192)(cid:103)(cid:205)(cid:210)(cid:192)(cid:151)(cid:174)(cid:202)
(cid:37)
(cid:44)
(cid:35)
(cid:38)
(cid:25)
(cid:37)
(cid:43)
(cid:35)
(cid:38)
(cid:25)
(cid:39)
(cid:42)
(cid:35)
(cid:38)
(cid:25)
(cid:39)
(cid:41)
(cid:35)
(cid:38)
(cid:25)
(cid:41)
(cid:40)
(cid:35)
(cid:38)
(cid:25)
(cid:21) (cid:37)(cid:40)(cid:21) (cid:37)(cid:41)(cid:21) (cid:37)(cid:42)(cid:21) (cid:37)(cid:43)(cid:21) (cid:37)(cid:44)
F
I
N
A
N
C
I
A
L
S
Consolidated Balance Sheets
ELI LILLY AND COMPANY AND SUBSIDIARIES
(Dollars in millions)
December 31
2007
2006
Assets
Current Assets
Cash and cash equivalents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Short-term investments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Accounts receivable, net of allowances of $103.1 (2007) and $82.5 (2006). . .
Other receivables (Note 8) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Inventories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Deferred income taxes (Note 11) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Prepaid expenses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total current assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other Assets
Prepaid pension (Note 12) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Investments (Note 5) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Goodwill and other intangibles—net (Note 3) . . . . . . . . . . . . . . . . . . . . . . . . . . .
Sundry (Note 8). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 3,220.5
1,610.7
2,673.9
1,030.9
2,523.7
583.6
613.6
12,256.9
$ 3,109.3
781.7
2,298.6
395.8
2,270.3
519.2
319.5
9,694.4
1,670.5
577.1
2,455.4
1,252.8
5,955.8
1,091.5
1,001.9
130.0
1,885.3
4,108.7
Property and Equipment, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
8,575.1
$26,787.8
8,152.3
$21,955.4
Liabilities and Shareholders’ Equity
Current Liabilities
Short-term borrowings and current maturities of long-term debt (Note 6) . . .
Accounts payable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Employee compensation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Sales rebates and discounts. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Dividends payable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Income taxes payable (Note 11) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other current liabilities (Note 8) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total current liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other Liabilities
Long-term debt (Note 6) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Accrued retirement benefi t (Note 12) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Long-term income taxes payable (Note 11) . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Deferred income taxes (Note 11) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other noncurrent liabilities (Note 8) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 413.7
1,018.5
823.8
706.8
513.6
238.4
1,553.5
5,268.3
$ 219.4
789.4
641.6
508.3
463.3
640.6
1,822.9
5,085.5
4,593.5
1,145.1
1,196.7
287.5
632.3
7,855.1
3,494.4
1,586.9
—
62.2
745.7
5,889.2
Commitments and contingencies (Note 13)
Shareholders’ Equity (Notes 7 and 9)
Common stock—no par value
Authorized shares: 3,200,000,000
Issued shares: 1,135,212,894 (2007) and 1,132,578,231 (2006). . . . . . . . . . .
Additional paid-in capital . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Retained earnings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Employee benefi t trust . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Deferred costs—ESOP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Accumulated other comprehensive income (loss) (Note 14). . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
709.5
3,805.2
11,967.2
(2,635.0)
(95.2)
13.2
13,764.9
707.9
3,571.9
10,926.7
(2,635.0)
(100.7)
(1,388.7)
11,082.1
Less cost of common stock in treasury
2007—899,445 shares
2006—909,573 shares. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
See notes to consolidated fi nancial statements.
100.5
13,664.4
$26,787.8
101.4
10,980.7
$21,955.4
19
S
L
A
I
C
N
A
N
I
F
Consolidated Statements of Cash Flows
ELI LILLY AND COMPANY AND SUBSIDIARIES
(Dollars in millions)
Year Ended December 31
2007
2006
2005
Cash Flows From Operating Activities
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Adjustments To Reconcile Net Income To Cash Flows
From Operating Activities
Depreciation and amortization . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Change in deferred taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Stock-based compensation expense . . . . . . . . . . . . . . . . . . . . . . . .
Acquired in-process research and development, net of tax . . . . .
Asset impairments, restructuring, and other special charges,
net of tax . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Changes in operating assets and liabilities, net of acquisitions
Receivables—(increase) decrease . . . . . . . . . . . . . . . . . . . . . . . .
Inventories—(increase) decrease. . . . . . . . . . . . . . . . . . . . . . . . .
Other assets—increase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Accounts payable and other liabilities—increase (decrease) . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$2,953.0
$2,662.7
$1,979.6
1,047.9
122.9
282.0
692.6
181.5
(8.4)
5,271.5
(842.7)
154.3
(355.8)
927.2
(117.0)
801.8
346.8
359.3
—
797.4
(196.8)
4,771.2
243.9
(60.2)
(43.0)
(936.0)
(795.3)
726.4
(347.5)
403.5
—
1,128.7
(30.0)
3,860.7
(286.4)
72.1
(269.4)
(1,463.4)
(1,947.1)
Net Cash Provided by Operating Activities . . . . . . . . . . . . . . . . . . . . .
5,154.5
3,975.9
1,913.6
Cash Flows From Investing Activities
Purchases of property and equipment . . . . . . . . . . . . . . . . . . . . . . . . .
Disposals of property and equipment . . . . . . . . . . . . . . . . . . . . . . . . . .
Net (repayments) proceeds of short-term investments . . . . . . . . . . .
Proceeds from sales and maturities of noncurrent investments . . .
Purchases of noncurrent investments . . . . . . . . . . . . . . . . . . . . . . . . .
Purchases of in-process research and development . . . . . . . . . . . . .
Cash paid for acquisitions, net of cash acquired . . . . . . . . . . . . . . . . .
Other, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net Cash Provided by (Used for) Investing Activities . . . . . . . . . . . .
Cash Flows From Financing Activities
Dividends paid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net repayments of short-term borrowings . . . . . . . . . . . . . . . . . . . . .
Proceeds from issuance of long-term debt . . . . . . . . . . . . . . . . . . . . .
Repayments of long-term debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Purchases of common stock . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Issuances of common stock under stock plans . . . . . . . . . . . . . . . . . .
Other, net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net Cash Used for Financing Activities . . . . . . . . . . . . . . . . . . . . . . . .
(1,082.4)
32.3
(376.9)
800.1
(750.7)
(111.0)
(2,673.2)
(166.3)
(4,328.1)
(1,853.6)
(468.5)
2,512.6
(1,059.5)
—
24.7
(0.6)
(844.9)
(1,077.8)
65.2
1,247.5
1,507.7
(1,313.2)
—
—
179.0
608.4
(1,736.3)
(8.4)
—
(2,781.5)
(122.1)
59.6
9.9
(4,578.8)
(1,298.1)
11.1
62.7
545.1
(1,183.1)
—
—
(353.6)
(2,215.9)
(1,654.9)
(1,988.7)
3,000.0
(1,004.7)
(377.9)
105.9
39.8
(1,880.5)
Effect of exchange rate changes on cash . . . . . . . . . . . . . . . . . . . . . . .
129.7
97.1
(175.8)
Net increase (decrease) in cash and cash equivalents . . . . . . . . . . . .
Cash and cash equivalents at beginning of year . . . . . . . . . . . . . . . . .
Cash and Cash Equivalents at End of Year . . . . . . . . . . . . . . . . . . . . .
111.2
3,109.3
$3,220.5
102.6
3,006.7
$3,109.3
(2,358.6)
5,365.3
$3,006.7
See notes to consolidated fi nancial statements.
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Consolidated Statements of Comprehensive Income
ELI LILLY AND COMPANY AND SUBSIDIARIES
(Dollars in millions)
Year Ended December 31
2007
2006
2005
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other comprehensive income (loss)
Foreign currency translation gains (losses) . . . . . . . . . . . . . . . . . .
Net unrealized gains (losses) on securities . . . . . . . . . . . . . . . . . . .
Minimum pension liability adjustment (Note 12) . . . . . . . . . . . . . . .
Defi ned benefi t pension and retiree health benefi t
plans (Note 12) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Effective portion of cash fl ow hedges. . . . . . . . . . . . . . . . . . . . . . . .
$2,953.0
$2,662.7
$1,979.6
756.6
(11.4)
—
943.8
(0.1)
542.4
(3.2)
(18.8)
—
143.3
(533.4)
0.3
(87.8)
—
(81.7)
Other comprehensive income (loss) before income taxes . . . . . . . . .
Provision for income taxes related to other comprehensive
1,688.9
663.7
(702.6)
income (loss) items . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other comprehensive income (loss) (Note 14) . . . . . . . . . . . . . . . . . . .
(287.0)
1,401.9
(43.1)
620.6
63.4
(639.2)
Comprehensive income. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$4,354.9
$3,283.3
$1,340.4
See notes to consolidated fi nancial statements.
portion of these risks through a controlled program of
risk management that includes the use of derivative
fi nancial instruments. The objective of controlling these
risks is to limit the impact on earnings of fl uctuations
in interest and currency exchange rates. All derivative
activities are for purposes other than trading.
Our primary interest rate risk exposure results
from changes in short-term U.S. dollar interest rates.
In an effort to manage interest rate exposures, we
strive to achieve an acceptable balance between fi xed
and fl oating rate debt positions and may enter into
interest rate derivatives to help maintain that balance.
Based on our overall interest rate exposure at Decem-
ber 31, 2007 and 2006, including derivatives and other
interest rate risk-sensitive instruments, a hypothetical
10 percent change in interest rates applied to the fair
value of the instruments as of December 31, 2007 and
2006, respectively, would have no material impact on
earnings, cash fl ows, or fair values of interest rate risk-
sensitive instruments over a one-year period.
Our foreign currency risk exposure results from
fl uctuating currency exchange rates, primarily the U.S.
dollar against the euro and the Japanese yen, and the
British pound against the euro. We face transactional
currency exposures that arise when we enter into
transactions, generally on an intercompany basis, de-
nominated in currencies other than the local currency.
We also face currency exposure that arises from trans-
lating the results of our global operations to the U.S.
dollar at exchange rates that have fl uctuated from the
beginning of the period. We use forward contracts and
purchased options to manage our foreign currency ex-
posures. Our policy outlines the minimum and maximum
hedge coverage of such exposures. Gains and losses on
these derivative positions offset, in part, the impact of
currency fl uctuations on the existing assets, liabilities,
commitments, and anticipated revenues. Consider-
ing our derivative fi nancial instruments outstanding at
December 31, 2007 and 2006, a hypothetical 10 percent
change in exchange rates (primarily against the U.S.
dollar) as of December 31, 2007 and 2006, respectively,
would have no material impact on earnings, cash fl ows,
or fair values of foreign currency rate risk-sensitive
instruments over a one-year period. These calculations
do not refl ect the impact of the exchange gains or losses
on the underlying positions that would be offset, in part,
by the results of the derivative instruments.
Off-Balance Sheet Arrangements and Contractual
Obligations
We have no off-balance sheet arrangements that have
a material current effect or that are reasonably likely to
have a material future effect on our fi nancial condition,
changes in fi nancial condition, revenues or expenses,
results of operations, liquidity, capital expenditures, or
capital resources. We acquire and partner assets still in
development and enter into research and development
arrangements with third parties that often require mile-
stone and royalty payments to the third party contingent
upon the occurrence of certain future events linked to
the success of the asset in development. Milestone pay-
ments may be required contingent upon the successful
achievement of an important point in the development
life cycle of the pharmaceutical product (e.g., approval
of the product for marketing by the appropriate regula-
tory agency or upon the achievement of certain sales
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Our current noncancelable contractual obligations that will require future cash payments are as follows (in millions):
Total
Less Than
1 Year
Payments Due by Period
1–3
Years
3–5
Years
More Than
5 Years
Long-term debt, including interest
payments1 . . . . . . . . . . . . . . . . . . . . $ 9,582.3
72.5
Capital lease obligations. . . . . . . . . . .
305.4
Operating leases . . . . . . . . . . . . . . . . .
Purchase obligations2 . . . . . . . . . . . . .
5,101.7
Other long-term liabilities
refl ected on our balance sheet3 . .
829.3
Other4 . . . . . . . . . . . . . . . . . . . . . . . . . .
146.3
Total . . . . . . . . . . . . . . . . . . . . . . . . . . . . $16,037.5
$ 645.6
15.5
93.7
4,575.5
—
146.3
$5,476.6
$ 522.4
20.3
129.5
330.3
154.3
—
$1,156.8
$1,000.7
5.8
76.2
149.7
159.7
—
$7,413.6
30.9
6.0
46.2
515.3
—
$1,392.1
$8,012.0
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1Our long-term debt obligations include both our expected principal and interest obligations and our interest rate swaps. We used the
interest rate forward curve at December 31, 2007 to compute the amount of the contractual obligation for interest on the variable rate
debt instruments and swaps.
2We have included the following:
• Purchase obligations, consisting primarily of all open purchase orders at our signifi cant operating locations as of December 31,
2007. Some of these purchase orders may be cancelable; however, for purposes of this disclosure, we have not distinguished
between cancelable and noncancelable purchase obligations.
• Contractual payment obligations with each of our signifi cant vendors, which are noncancelable and are not contingent.
3We have included our long-term liabilities consisting primarily of our nonqualifi ed supplemental pension funding requirements and
deferred compensation liabilities. Liabilities for unrecognized tax benefi ts of $1.57 billion are excluded as reasonable estimates could
not be made regarding the timing of future cash outfl ows associated with those liabilities.
4This category comprises primarily minimum pension funding requirements.
The contractual obligations table is current as of December 31, 2007. The amount of these obligations can be
expected to change materially over time as new contracts are initiated and existing contracts are completed, ter-
minated, or modifi ed.
levels). If required by the arrangement, we may have to
make royalty payments based upon a percentage of the
sales of the pharmaceutical product in the event that
regulatory approval for marketing is obtained. Because
of the contingent nature of these payments, they are not
included in the table of contractual obligations.
Individually, these arrangements are not material
in any one annual reporting period. However, if mile-
stones for multiple products covered by these arrange-
ments would happen to be reached in the same report-
ing period, the aggregate charge to expense could be
material to the results of operations in any one period.
The inherent risk in pharmaceutical development
makes it unlikely that this will occur, as the failure rate
for products in development is very high. In addition,
these arrangements often give us the discretion to uni-
laterally terminate development of the product, which
would allow us to avoid making the contingent pay-
ments; however, we are unlikely to cease development
if the compound successfully achieves clinical testing
objectives. We also note that, from a business perspec-
tive, we view these payments as positive because they
signify that the product is successfully moving through
development and is now generating or is more likely to
generate cash fl ows from sales of products.
APPLICATION OF CRITICAL ACCOUNTING POLICIES
In preparing our fi nancial statements in accordance
with generally accepted accounting principles (GAAP),
we must often make estimates and assumptions that
affect the reported amounts of assets, liabilities,
revenues, expenses, and related disclosures. Some of
those judgments can be subjective and complex, and
consequently actual results could differ from those
estimates. For any given individual estimate or as-
sumption we make, it is possible that other people
applying reasonable judgment to the same facts and
circumstances could develop different estimates. We
believe that, given current facts and circumstances,
it is unlikely that applying any such other reasonable
judgment would cause a material adverse effect on our
consolidated results of operations, fi nancial position,
or liquidity for the periods presented in this report. Our
most critical accounting policies have been discussed
with our audit committee and are described below.
Revenue Recognition and Sales Rebate and Discount
Accruals
We recognize revenue from sales of products at the
time title of goods passes to the buyer and the buyer
assumes the risks and rewards of ownership. For more
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than 90 percent of our sales, this is at the time prod-
ucts are shipped to the customer, typically a wholesale
distributor or a major retail chain. The remaining sales
are recorded at the point of delivery. Provisions for dis-
counts and rebates are established in the same period
the related sales are recorded.
We regularly review the supply levels of our sig-
nifi cant products sold to major wholesalers in the U.S.
and in major markets outside the U.S., primarily by
reviewing periodic inventory reports supplied by our
major wholesalers and available prescription volume
information for our products, or alternative approaches.
We attempt to maintain wholesaler inventory levels at
an average of approximately one month or less on a
consistent basis across our product portfolio. Causes
of unusual wholesaler buying patterns include actual
or anticipated product supply issues, weather patterns,
anticipated changes in the transportation network,
redundant holiday stocking, and changes in wholesaler
business operations. An unusual buying pattern com-
pared with underlying demand of our products outside
the U.S. could also be the result of speculative buying
by wholesalers in anticipation of price increases. When
we believe wholesaler purchasing patterns have caused
an unusual increase or decrease in the sales of a major
product compared with underlying demand, we dis-
close this in our product sales discussion if the amount
is believed to be material to the product sales trend;
however, we are not always able to accurately quantify
the amount of stocking or destocking.
As a result of restructuring our arrangements with
our U.S. wholesalers in early 2005, reductions occurred
in wholesaler inventory levels for certain products
(primarily Strattera, Prozac, and Gemzar) that reduced
our 2005 sales by approximately $170 million. The
modifi ed structure eliminates the incentive for specula-
tive wholesaler buying and provides us improved data
on inventory levels at our U.S. wholesalers. Wholesaler
stocking and destocking activity historically has not
caused any material changes in the rate of actual prod-
uct returns, which have been approximately 1 percent
of our net sales over the past three years and have not
fl uctuated signifi cantly as a percent of sales.
We establish sales rebate and discount accruals in
the same period as the related sales. The rebate/dis-
count amounts are recorded as a deduction to arrive at
our net sales. Sales rebates/discounts that require the
use of judgment in the establishment of the accrual in-
clude Medicaid, managed care, Medicare, chargebacks,
long-term-care, hospital, patient assistance programs,
and various other government programs. We base
these accruals primarily upon our historical rebate/dis-
count payments made to our customer segment groups
and the provisions of current rebate/discount contracts.
The largest of our sales rebate/discount amounts
are rebates associated with sales covered by Medicaid. In
determining the appropriate accrual amount, we consid-
er our historical Medicaid rebate payments by product as
a percentage of our historical sales as well as any signifi -
cant changes in sales trends, an evaluation of the current
Medicaid rebate laws and interpretations, the percent-
age of our products that are sold to Medicaid recipients,
and our product pricing and current rebate/discount
contracts. Although we accrue a liability for Medicaid
rebates at the time we record the sale (when the prod-
uct is shipped), the Medicaid rebate related to that sale
is typically paid up to six months later. Due to the time
lag, in any particular period our rebate adjustments may
incorporate revisions of accruals for several periods.
Most of our rebates outside the U.S. are contractual
or legislatively mandated and are estimated and recog-
nized in the same period as the related sales. In some
large European countries, government rebates are
based on the anticipated pharmaceutical budget defi cit
in the country. A best estimate of these rebates, updated
as governmental authorities revise budgeted defi cits, is
recognized in the same period as the related sale. If our
estimates are not refl ective of the actual pharmaceuti-
cal budget defi cit, we adjust our rebate reserves.
We believe that our accruals for sales rebates and
discounts are reasonable and appropriate based on
current facts and circumstances. Federally mandated
Medicaid rebate and state pharmaceutical assistance
programs (Medicaid) and Medicare rebates reduced
sales by $642.1 million, $571.7 million, and $637.1 mil-
lion in 2007, 2006, and 2005, respectively. A 5 percent
change in the Medicaid and Medicare rebate amounts
we recognized in 2007 would lead to an approximate
$32 million effect on our income before income taxes.
As of December 31, 2007, our Medicaid and Medicare
rebate liability was $308.8 million.
Approximately 75 percent and 85 percent of our
global rebate and discount liability resulted from sales
of our products in the U.S. as of December 31, 2007 and
2006, respectively. The following represents a roll-for-
ward of our most signifi cant U.S. rebate and discount
liability balances, including Medicaid (in millions):
2007
2006
Rebate and discount liability,
beginning of year. . . . . . . . . . . . $ 383.3
Reduction of net sales
$ 379.4
due to discounts and
rebates1 . . . . . . . . . . . . . . . . .
1,314.1
1,246.1
Cash payments of discounts
and rebates . . . . . . . . . . . . .
(1,228.6)
(1,242.2)
Rebate and discount liability,
end of year . . . . . . . . . . . . . . . . . $ 468.8 $ 383.3
1Adjustments of the estimates for these rebates and discounts to
actual results were less than 0.3 percent of net sales for each of
the years presented.
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Product Litigation Liabilities and Other Contingencies
Product litigation liabilities and other contingencies are,
by their nature, uncertain and are based upon complex
judgments and probabilities. The factors we consider
in developing our product litigation liability reserves
and other contingent liability amounts include the
merits and jurisdiction of the litigation, the nature and
the number of other similar current and past litigation
cases, the nature of the product and the current as-
sessment of the science subject to the litigation, and the
likelihood of settlement and current state of settlement
discussions, if any. In addition, we accrue for certain
product liability claims incurred, but not fi led, to the
extent we can formulate a reasonable estimate of their
costs. We estimate these expenses based primarily on
historical claims experience and data regarding product
usage. We accrue legal defense costs expected to be
incurred in connection with signifi cant product liability
contingencies when probable and reasonably estimable.
We also consider the insurance coverage we have
to diminish the exposure for periods covered by insur-
ance. In assessing our insurance coverage, we consider
the policy coverage limits and exclusions, the potential
for denial of coverage by the insurance company, the
fi nancial position of the insurers, and the possibility of
and the length of time for collection.
The litigation accruals and environmental liabilities
and the related estimated insurance recoverables have
been refl ected on a gross basis as liabilities and assets,
respectively, on our consolidated balance sheets.
We believe that the accruals and related insurance
recoveries we have established for product litigation li-
abilities and other contingencies are appropriate based
on current facts and circumstances.
Pension and Retiree Medical Plan Assumptions
Pension benefi t costs include assumptions for the dis-
count rate, retirement age, and expected return on plan
assets. Retiree medical plan costs include assumptions
for the discount rate, retirement age, expected return
on plan assets, and health-care-cost trend rates. These
assumptions have a signifi cant effect on the amounts
reported. In addition to the analysis below, see Note 12
to the consolidated fi nancial statements for additional
information regarding our retirement benefi ts.
Periodically, we evaluate the discount rate and the
expected return on plan assets in our defi ned benefi t
pension and retiree health benefi t plans. In evaluating
these assumptions, we consider many factors, includ-
ing an evaluation of the discount rates, expected return
on plan assets and the health-care-cost trend rates of
other companies; our historical assumptions compared
with actual results; an analysis of current market con-
ditions and asset allocations (approximately 85 percent
to 95 percent of which are growth investments); and the
views of leading fi nancial advisers and economists. We
24
use an actuarially determined, company-specifi c yield
curve to determine the discount rate. In evaluating our
expected retirement age assumption, we consider the
retirement ages of our past employees eligible for pen-
sion and medical benefi ts together with our expecta-
tions of future retirement ages.
We believe our pension and retiree medical plan as-
sumptions are appropriate based upon the above factors.
If the health-care-cost trend rates were to be increased
by one percentage point each future year, the aggregate
of the service cost and interest cost components of the
2007 annual expense would increase by approximately
$28 million. A one-percentage-point decrease would
lower the aggregate of the 2007 service cost and interest
cost by approximately $23 million. If the 2007 discount
rate for the U.S. defi ned benefi t pension and retiree
health benefi t plans (U.S. plans) were to be changed by
a quarter percentage point, income before income taxes
would change by approximately $32 million. If the 2007
expected return on plan assets for U.S. plans were to be
changed by a quarter percentage point, income before
income taxes would change by approximately $14 million.
If our assumption regarding the 2007 expected age of
future retirees for U.S. plans were adjusted by one year,
our income before income taxes would be affected by
approximately $31 million. The U.S. plans represent ap-
proximately 80 percent of the total accumulated postre-
tirement benefi t obligation and approximately 83 percent
of total plan assets at December 31, 2007.
Impairment of Long-lived Assets
We review the carrying value of long-lived assets for
potential impairment on a periodic basis and whenever
events or changes in circumstances indicate the carrying
value of an asset may not be recoverable. Impairment is
determined by comparing projected undiscounted cash
fl ows to be generated by the asset to its carrying value.
If an impairment is identifi ed, a loss is recorded equal to
the excess of the asset’s net book value over its fair value,
and the cost basis is adjusted. The estimated future cash
fl ows, based on reasonable and supportable assumptions
and projections, require management’s judgment. Actual
results could vary from these estimates.
Income Taxes
We prepare and fi le tax returns based on our interpreta-
tion of tax laws and regulations and record estimates
based on these judgments and interpretations. In the
normal course of business, our tax returns are subject
to examination by various taxing authorities, which may
result in future tax, interest, and penalty assessments
by these authorities. Inherent uncertainties exist in es-
timates of many tax positions due to changes in tax law
resulting from legislation, regulation and/or as conclud-
ed through the various jurisdictions’ tax court systems.
We recognize the tax benefi t from an uncertain tax posi-
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tion only if it is more likely than not that the tax position
will be sustained on examination by the taxing authori-
ties, based on the technical merits of the position. The
tax benefi ts recognized in the fi nancial statements from
such a position are measured based on the largest
benefi t that has a greater than 50 percent likelihood of
being realized upon ultimate resolution. The amount
of unrecognized tax benefi ts is adjusted for changes in
facts and circumstances. For example, adjustments
could result from signifi cant amendments to existing tax
law and the issuance of regulations or interpretations by
the taxing authorities, new information obtained during
a tax examination, or resolution of an examination. We
believe that our estimates for uncertain tax positions
are appropriate and suffi cient to pay assessments that
may result from examinations of our tax returns. We
recognize both accrued interest and penalties related
to unrecognized tax benefi ts in income tax expense.
We have recorded valuation allowances against
certain of our deferred tax assets, primarily those
that have been generated from net operating losses in
certain taxing jurisdictions. In evaluating whether we
would more likely than not recover these deferred tax
assets, we have not assumed any future taxable income
or tax planning strategies in the jurisdictions associ-
ated with these carryforwards where history does not
support such an assumption. Implementation of tax
planning strategies to recover these deferred tax assets
or future income generation in these jurisdictions could
lead to the reversal of these valuation allowances and a
reduction of income tax expense.
We believe that our estimates for the uncertain tax
positions and valuation allowances against the deferred
tax assets are appropriate based on current facts and
circumstances. A 5 percent change in the amount of
the uncertain tax positions and the valuation allowance
would result in a change in net income of approximately
$78 million and $26 million, respectively.
FINANCIAL EXPECTATIONS FOR 2008
For the full year of 2008, we expect earnings per share to
be in the range of $3.80 to $3.95. This guidance includes
the anticipated acquired in-process research and devel-
opment charges of $.05 related to the BioMS in-licens-
ing agreement. We expect sales to grow in the mid-to
high-single digits, driven primarily by increased volume
and strong sales growth for Cymbalta, Cialis, Byetta,
Alimta, and Humalog. We expect modest improvement
in gross margin as a percent of net sales, driven primar-
ily by manufacturing expenses growing more slowly
than sales. In addition, we expect operating expenses to
grow more slowly than sales in 2008, with growth in the
mid-single digits. Marketing, selling, and administrative
expenses are expected to grow in the low-single digits,
driven by investments in prasugrel, Cymbalta, Evista
for invasive breast cancer risk reduction, Humalog, and
Byetta, offset by decreases in other areas. Research and
development expenses are expected to grow in the high-
single to low-double digits. Other income—net is expected
to contribute less than $100 million. The effective tax
rate is expected to be approximately 23 percent. We ex-
pect capital expenditures of approximately $1.1 billion.
Actual results could differ materially and will
depend on, among other things, the continuing growth
of our currently marketed products; developments with
competitive products; the timing and scope of regula-
tory approvals and the success of our new product
launches; asset impairments, restructurings, and
acquisitions of compounds under development result-
ing in acquired in-process research and development
charges; foreign exchange rates; changes in effec-
tive tax rates; wholesaler inventory changes; other
regulatory developments, litigation, and government
investigations; and the impact of governmental actions
regarding pricing, importation, and reimbursement for
pharmaceuticals. We undertake no duty to update these
forward-looking statements.
LEGAL AND REGULATORY MATTERS
We are a party to various legal actions and govern-
ment investigations. The most signifi cant of these are
described below. While it is not possible to determine
the outcome of these matters, we believe that, except
as specifi cally noted below, the resolution of all such
matters will not have a material adverse effect on our
consolidated fi nancial position or liquidity, but could
possibly be material to our consolidated results of
operations in any one accounting period.
Patent Litigation
We are engaged in the following patent litigation mat-
ters brought pursuant to procedures set out in the
Hatch-Waxman Act (the Drug Price Competition and
Patent Term Restoration Act of 1984):
• Barr Laboratories, Inc. (Barr), submitted an Abbreviated
New Drug Application (ANDA) in 2002 seeking
permission to market a generic version of Evista prior
to the expiration of our relevant U.S. patents (expiring
in 2012-2017) and alleging that these patents are
invalid, not enforceable, or not infringed. In November
2002, we fi led a lawsuit against Barr in the U.S. District
Court for the Southern District of Indiana, seeking a
ruling that these patents are valid, enforceable, and
being infringed by Barr. Teva has also submitted an
ANDA seeking permission to market a generic version
of Evista. In June 2006, we fi led a similar lawsuit
against Teva in the U.S. District Court for the Southern
District of Indiana. The lawsuit against Teva is currently
scheduled for trial beginning March 9, 2009, while no
trial date has been set in the lawsuit against Barr.
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We believe that Barr’s and Teva’s claims are without
merit and we expect to prevail. However, it is not
possible to determine the outcome of this litigation,
and accordingly, we can provide no assurance that
we will prevail. An unfavorable outcome could have a
material adverse impact on our consolidated results
of operations, liquidity, and fi nancial position.
• Sicor Pharmaceuticals, Inc. (Sicor), Mayne Pharma
(USA) Inc. (Mayne), and Sun Pharmaceutical Industries
Inc. (Sun) each submitted ANDAs seeking permission
to market generic versions of Gemzar prior to the
expiration of our relevant U.S. patents (compound
patent expiring in 2010 and method-of-use patent
expiring in 2013), and alleging that these patents are
invalid. We fi led lawsuits in the U.S. District Court
for the Southern District of Indiana against Sicor
(February 2006) and Mayne (October 2006), seeking
rulings that these patents are valid and are being
infringed. In November 2007, the lawsuit against
Mayne was stayed and administratively closed by the
court. Also in November 2007, Sun fi led a declaratory
judgment action in the United States District Court for
the Eastern District of Michigan, seeking a ruling that
our method-of-use patent is invalid or unenforceable,
or would not be infringed by the sale of Sun’s generic
product. Sun informed us in December 2007 that it is
also challenging our compound patent, and that patent
has now been added to the declaratory judgment
action. In January 2008, we fi led a second lawsuit
against Mayne in response to a second ANDA fi led by
Mayne for a new dosage strength. We expect to prevail
in this litigation and believe that these claims are
without merit. However, it is not possible to determine
the outcome of this litigation, and accordingly, we
can provide no assurance that we will prevail. An
unfavorable outcome could have a material adverse
impact on our consolidated results of operations,
liquidity, and fi nancial position.
• Actavis Elizabeth LLC (Actavis), Glenmark Pharma-
ceuticals Inc., USA (Glenmark), Sun Pharmaceutical
Industries Limited (Sun), Sandoz Inc. (Sandoz), Mylan
Pharmaceuticals Inc. (Mylan), Teva Pharmaceuticals
USA, Inc. (Teva), Apotex Inc. (Apotex), Aurobindo
Pharma Ltd. (Aurobindo), Synthon Laboratories, Inc.
(Synthon), and Zydus Pharmaceuticals, USA, Inc.
(Zydus) each submitted an ANDA seeking permission
to market generic versions of Strattera prior to the
expiration of our relevant U.S. patent (expiring in
2017), and alleging that this patent is invalid. We fi led
a lawsuit against Actavis in the United States District
Court for the District of New Jersey in August 2007.
Sandoz fi led a declaratory judgment action in the same
court, but its case has been dismissed. In September
2007, we amended the complaint in the New Jersey
lawsuit to add Glenmark, Sun, Sandoz, Mylan, Teva,
Apotex, Aurobindo, Synthon, and Zydus as defendants.
26
We fi led a second action against Synthon in the United
States District Court for the Eastern District of Virginia.
Synthon has fi led a motion to dismiss our lawsuit in
New Jersey. In December 2007, Zydus agreed to entry
of a consent judgment in which Zydus conceded the
validity and enforceability of the patent and agreed to
a permanent injunction. We expect to prevail in this
litigation and believe that these claims are without
merit. However, it is not possible to determine
the outcome of this litigation, and accordingly, we
can provide no assurance that we will prevail. An
unfavorable outcome could have a material adverse
impact on our consolidated results of operations,
liquidity, and fi nancial position.
We have received challenges to Zyprexa patents in
a number of countries outside the U.S.:
• In Canada, several generic pharmaceutical
manufacturers have challenged the validity of our
Zyprexa compound and method-of-use patent (expiring
in 2011). In April 2007, the Canadian Federal Court
ruled against the fi rst challenger, Apotex Inc. (Apotex),
and Apotex has appealed that ruling. In June 2007,
the Canadian Federal Court held that the invalidity
allegations of a second challenger, Novopharm
Ltd. (Novopharm), were justifi ed and denied our
request that Novopharm be prohibited from receiving
marketing approval for generic olanzapine in Canada.
Novopharm began selling generic olanzapine in
Canada in the third quarter of 2007. We have appealed
that decision and sued Novopharm for patent
infringement. The appeal was dismissed. In November
2007, Apotex fi led an action seeking a declaration of
the invalidity of our Zyprexa compound and method-of-
use patents (expiring in 2011). The trial court ruled in
our favor in February 2007. Apotex will likely appeal.
• In Germany, generic pharmaceutical manufacturers
Egis-Gyogyszergyar and Neolabs Ltd. challenged the
validity of our Zyprexa compound and method-of-use
patents (expiring in 2011). In June 2007, the German
Federal Patent Court held that our patent is invalid.
We are appealing the decision. Generic olanzapine
was launched by competitors in Germany in the fourth
quarter of 2007.
• We have received challenges in a number of other
countries, including Spain, the United Kingdom (U.K.),
and several smaller European countries. In Spain, we
have been successful at both the trial and appellate
court levels in defeating the generic manufacturers’
challenge, but we anticipate further legal challenges
from generic manufacturers. In the U.K., a trial date
has tentatively been set for July 2008.
We are vigorously contesting the various legal chal-
lenges to our Zyprexa patents on a country-by-country
basis. We cannot determine the outcome of this litiga-
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tion. The availability of generic olanzapine in Canada
and Germany will have a material adverse impact on
our consolidated results of operations. The availability
of generic olanzapine in additional markets could have a
material adverse impact on our consolidated results of
operations.
In June 2002, Ariad Pharmaceuticals, Inc., the
Massachusetts Institute of Technology, the Whitehead
Institute for Biomedical Research, and the President
and Fellows of Harvard College in the U.S. District
Court for the District of Massachusetts sued us, alleg-
ing that sales of two of our products, Xigris® and Evista,
were inducing the infringement of a patent related to
the discovery of a natural cell signaling phenomenon
in the human body, and seeking royalties on past and
future sales of these products. On May 4, 2006, a jury in
Boston issued an initial decision in the case that Xigris
and Evista sales infringe the patent. The jury awarded
the plaintiffs approximately $65 million in damages,
calculated by applying a 2.3 percent royalty to all U.S.
sales of Xigris and Evista from the date of issuance
of the patent through the date of trial. In addition, a
separate bench trial with the U.S. District Court of Mas-
sachusetts was held in August 2006, on our contention
that the patent is unenforceable and impermissibly cov-
ers natural processes. In June 2005, the United States
Patent and Trademark Offi ce (USPTO) commenced a re-
examination of the patent, and in August 2007 took the
position that the Ariad claims at issue are unpatentable,
a position that Ariad continues to contest. In September
2007, the Court entered a fi nal judgment indicating that
Ariad’s claims are patentable, valid, and enforceable,
and fi nding damages in the amount of $65 million plus a
2.3 percent royalty on net U.S. sales of Xigris and Evista
since the time of the jury decision. However, the Court
deferred the requirement to pay any damages until after
all rights to appeal have been exhausted. We plan to
appeal this judgment. We believe that these allegations
are without legal merit, that we will ultimately prevail
on these issues, and therefore that the likelihood of any
monetary damages is remote.
Government Investigations and Related Litigation
In March 2004, the Offi ce of the U.S. Attorney for the
Eastern District of Pennsylvania (EDPA) advised us
that it had commenced an investigation related to our
U.S. marketing and promotional practices, including
our communications with physicians and remuneration
of physician consultants and advisors, with respect to
Zyprexa, Prozac, and Prozac Weekly. In November 2007,
we received a grand jury subpoena from the EDPA for a
broad range of documents related to Zyprexa. A number
of State Medicaid Fraud Control Units are coordinat-
ing with the EDPA in its investigation of any Medicaid-
related claims relating to our marketing and promotion
of Zyprexa. In October 2005, the EDPA advised that it
is also conducting an inquiry regarding certain rebate
agreements we entered into with a pharmacy benefi t
manager covering Axid®, Evista, Humalog, Humulin,
Prozac, and Zyprexa. The inquiry includes a review of
our Medicaid best price reporting related to the product
sales covered by the rebate agreements.
In June 2005, we received a subpoena from the
Offi ce of the Attorney General, Medicaid Fraud Control
Unit, of the State of Florida, seeking production of docu-
ments relating to sales of Zyprexa and our marketing
and promotional practices with respect to Zyprexa.
In September 2006, we received a subpoena from
the California Attorney General’s Offi ce seeking pro-
duction of documents related to our efforts to obtain
and maintain Zyprexa’s status on California’s formulary,
marketing and promotional practices with respect to
Zyprexa, and remuneration of health care providers.
In February 2007, we received a subpoena from the
Offi ce of the Attorney General of the State of Illinois,
seeking production of documents and information relat-
ing to sales of Zyprexa and our marketing and promo-
tional practices, including our communications with
physicians and remuneration of physician consultants
and advisors, with respect to Zyprexa.
Beginning in August 2006, we have received civil
investigative demands or subpoenas from the attorneys
general of a number of states under various state con-
sumer protection laws. Most of these requests are now
part of a multistate investigative effort being coordinat-
ed by an executive committee of attorneys general. We
are aware that approximately 30 states are participating
in this joint effort, and it is possible that additional states
will join the investigation. These attorneys general are
seeking a broad range of Zyprexa documents, including
documents relating to sales, marketing and promotion-
al practices, and remuneration of health care providers.
In addition, we have been named as a defendant in a pri-
vate suit in California State Court, which was removed
to federal court, alleging violations of the California
False Claims Act with respect to certain Zyprexa mar-
keting and promotional practices. This suit was brought
by an individual on behalf of the government, under the
qui tam provision of the California False Claims Act.
We are cooperating in each of these investigations,
including providing a broad range of documents and
information relating to the investigations. It is pos-
sible that other Lilly products could become subject
to investigation and that the outcome of these matters
could include criminal charges and fi nes, penalties, or
other monetary or nonmonetary remedies. We cannot
determine the outcome of these matters or reasonably
estimate the amount or range of amounts of any fi nes
or penalties that might result from an adverse outcome.
It is possible, however, that an adverse outcome could
have a material adverse impact on our consolidated re-
sults of operations, liquidity, and fi nancial position. We
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have implemented and continue to review and enhance
a broadly based compliance program that includes
comprehensive compliance-related activities designed
to ensure that our marketing and promotional practic-
es, physician communications, remuneration of health
care professionals, managed care arrangements, and
Medicaid best price reporting comply with applicable
laws and regulations.
Product Liability and Related Litigation
We have been named as a defendant in a large number
of Zyprexa product liability lawsuits in the United States
and have been notifi ed of many other claims of individu-
als who have not fi led suit. The lawsuits and unfi led
claims (together the “claims”) allege a variety of inju-
ries from the use of Zyprexa, with the majority alleging
that the product caused or contributed to diabetes or
high blood-glucose levels. The claims seek substantial
compensatory and punitive damages and typically ac-
cuse us of inadequately testing for and warning about
side effects of Zyprexa. Many of the claims also allege
that we improperly promoted the drug. Almost all of the
federal lawsuits are part of a Multi-District Litigation
(MDL) proceeding before The Honorable Jack Weinstein
in the Federal District Court for the Eastern District of
New York (MDL No. 1596).
Since June 2005, we have entered into agreements
with various claimants’ attorneys involved in U.S. Zyprexa
product liability litigation to settle a substantial majority
of the claims. The agreements cover a total of approxi-
mately 31,200 claimants, including a large number of
previously fi led lawsuits and other asserted claims. The
two primary settlements were as follows:
• In June 2005, we reached an agreement in principle
(and in September 2005 a fi nal agreement) to settle
more than 8,000 claims for $690.0 million plus
$10.0 million to cover administration of the
settlement.
• In January 2007, we reached agreements with a
number of plaintiffs’ attorneys to settle more than
18,000 claims for approximately $500 million.
The 2005 settlement totaling $700.0 million was
paid during 2005. The January 2007 settlements were
paid during 2007.
We are prepared to continue our vigorous defense
of Zyprexa in all remaining claims. The U.S. Zyprexa
product liability claims not subject to these agreements
include approximately 325 lawsuits in the U.S. covering
approximately 1,235 plaintiffs. Trial dates have been set
for June 23, 2008, in the Eastern District of New York,
for several of the U.S. plaintiffs.
In early 2005, we were served with four lawsuits
seeking class action status in Canada on behalf of
patients who took Zyprexa. One of these four lawsuits
has been certifi ed for residents of Quebec, and a second
28
has been certifi ed in Ontario and includes all Canadian
residents, except for residents of Quebec and British
Columbia. The allegations in the Canadian actions are
similar to those in the litigation pending in the U.S.
We have insurance coverage for a portion of our
Zyprexa product liability claims exposure. The third-
party insurance carriers have raised defenses to their
liability under the policies and are seeking to rescind
the policies. The dispute was the subject of litigation in
the federal court in Indianapolis against certain of the
carriers and in arbitration in Bermuda against other
carriers. In the second half of 2007, we reached settle-
ments resolving the vast majority of the disputed insur-
ance claims, and a portion of the insurance proceeds
were paid to us prior to the end of 2007.
Since the beginning of 2005, we have recorded ag-
gregate net pretax charges of $1.61 billion for Zyprexa
product liability matters. The net charges, which take
into account our actual and expected insurance recov-
eries, covered the following:
• The cost of the Zyprexa product liability settlements
to date; and
• Reserves for product liability exposures and defense
costs regarding the known Zyprexa product liability
claims and expected future claims to the extent
we could formulate a reasonable estimate of the
probable number and cost of the claims.
In December 2004, we were served with two
lawsuits brought in state court in Louisiana on behalf
of the Louisiana Department of Health and Hospitals,
alleging that Zyprexa caused or contributed to diabetes
or high blood-glucose levels, and that we improperly
promoted the drug. These cases have been removed to
federal court and are now part of the MDL proceedings
in the Eastern District of New York. In these actions, the
Department of Health and Hospitals seeks to recover
the costs it paid for Zyprexa through Medicaid and other
drug-benefi t programs, as well as the costs the de-
partment alleges it has incurred and will incur to treat
Zyprexa-related illnesses. We have been served with
similar lawsuits fi led by the states of Alaska, Mississip-
pi, Montana, New Mexico, Pennsylvania, South Carolina,
Utah, and West Virginia in the courts of the respective
states. The Mississippi, Montana, New Mexico, and West
Virginia cases have been removed to federal court and
are now part of the MDL proceedings in the Eastern
District of New York. The Alaska case is scheduled for
trial beginning March 3, 2008.
In 2005, two lawsuits were fi led in the Eastern
District of New York purporting to be nationwide class
actions on behalf of all consumers and third-party pay-
ors, excluding governmental entities, which have made
or will make payments for their members or insured
patients being prescribed Zyprexa. These actions have
now been consolidated into a single lawsuit, which is
brought under certain state consumer protection stat-
utes, the federal civil RICO statute, and common law
theories, seeking a refund of the cost of Zyprexa, treble
damages, punitive damages, and attorneys’ fees. Two
additional lawsuits were fi led in the Eastern District
of New York in 2006 on similar grounds. In 2007, The
Pennsylvania Employees Trust Fund brought claims in
state court in Pennsylvania as insurer of Pennsylvania
state employees, who were prescribed Zyprexa on simi-
lar grounds as described in the New York cases. As with
the product liability suits, these lawsuits allege that we
inadequately tested for and warned about side effects of
Zyprexa and improperly promoted the drug.
We cannot determine with certainty the additional
number of lawsuits and claims that may be asserted.
The ultimate resolution of Zyprexa product liability and
related litigation could have a material adverse impact
on our consolidated results of operations, liquidity, and
fi nancial position.
In addition, we have been named as a defendant
in numerous other product liability lawsuits involving
primarily diethylstilbestrol (DES) and thimerosal. The
majority of these claims are covered by insurance, sub-
ject to deductibles and coverage limits.
Because of the nature of pharmaceutical products,
it is possible that we could become subject to large
numbers of product liability and related claims for
other products in the future. In the past few years, we
have experienced diffi culties in obtaining product liabil-
ity insurance due to a very restrictive insurance market.
Therefore, for substantially all of our currently mar-
keted products, we have been and expect that we will
continue to be largely self-insured for future product
liability losses. In addition, as noted above, there is no
assurance that we will be able to fully collect from our
insurance carriers on past claims.
PRIVATE SECURITIES LITIGATION REFORM ACT OF
1995—A CAUTION CONCERNING FORWARD-LOOKING
STATEMENTS
Under the safe harbor provisions of the Private Securi-
ties Litigation Reform Act of 1995, we caution investors
that any forward-looking statements or projections
made by us, including those made in this document, are
based on management’s expectations at the time they
are made, but they are subject to risks and uncertain-
ties that may cause actual results to differ materially
from those projected. Economic, competitive, govern-
mental, technological, legal, and other factors that may
affect our operations and prospects are discussed ear-
lier in this section and our most recent report on Forms
10-Q and 10-K fi led with the Securities and Exchange
Commission. We undertake no duty to update forward-
looking statements.
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Segment Information
ELI LILLY AND COMPANY AND SUBSIDIARIES
(Dollars in millions)
We operate in one significant business segment—pharmaceutical products. Operations of the animal health busi-
ness segment are not material and share many of the same economic and operating characteristics as pharma-
ceutical products. Therefore, they are included with pharmaceutical products for purposes of segment reporting.
Year Ended December 31
2007
2006
2005
Net sales—to unaffiliated customers
Neurosciences. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Endocrinology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Oncology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cardiovascular2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Animal health . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other pharmaceuticals. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 7,851.0
5,479.6
2,446.4
1,624.1
$ 6,728.5
5,014.5
2,020.2
730.4
$ 6,080.0
4,636.9
1,801.0
778.8
995.8 875.5
236.6
$18,633.5
863.7
321.9
$15,691.0
484.9
$14,645.3
Geographic Information
Net sales—to unaffiliated customers1
United States . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Europe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other foreign countries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Long-lived assets
United States . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Europe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other foreign countries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$10,145.5
4,844.5
3,643.5
$18,633.5
$ 5,905.4
2,057.7
1,768.6
$ 9,731.7
$ 8,599.2
3,894.3
3,197.5
$15,691.0
$ 6,207.4
1,733.8
1,718.4
$ 9,659.6
$ 7,798.1
3,818.6
3,028.6
$14,645.3
$ 6,524.5
1,554.9
1,748.9
$ 9,828.3
1Net sales are attributed to the countries based on the location of the customer.
2Cialis sales for 2007 are included in Cardiovascular, and 2006 and 2005 Cialis sales have been reclassified from other pharmaceuti-
cals to be consistent with the 2007 presentation.
The largest category of products is the neurosciences group, which includes Zyprexa, Cymbalta, Strattera,
and Prozac. Endocrinology products consist primarily of Humalog, Humulin, Actos, Byetta, Evista, Forteo, and
Humatrope. Oncology products consist primarily of Gemzar and Alimta. Cardiovascular products consist primar-
ily of Cialis, ReoPro®, and Xigris. Animal health products include Tylan, Rumensin, Coban®, and other products
for livestock and poultry. The other pharmaceuticals category includes anti-infectives, primarily Ceclor® and
Vancocin®, and other miscellaneous pharmaceutical products and services.
Most of our pharmaceutical products are distributed through wholesalers that serve pharmacies, physicians
and other health care professionals, and hospitals. In 2007, our three largest wholesalers each accounted for be-
tween 12 percent and 16 percent of consolidated net sales. Further, they each accounted for between 9 percent and
13 percent of accounts receivable as of December 31, 2007. Animal health products are sold primarily to wholesale
distributors.
Our business segments are distinguished by the ultimate end user of the product: humans or animals. Per-
formance is evaluated based on profit or loss from operations before income taxes. The accounting policies of the
individual segments are substantially the same as those described in the summary of significant accounting poli-
cies in Note 1 to the consolidated financial statements. Income before income taxes for the animal health business
was approximately $173 million, $184 million, and $215 million in 2007, 2006, and 2005, respectively.
The assets of the animal health business are intermixed with those of the pharmaceutical products business.
Long-lived assets disclosed above consist of property and equipment and certain sundry assets.
We are exposed to the risk of changes in social, political, and economic conditions inherent in foreign opera-
tions, and our results of operations and the value of our foreign assets are affected by fluctuations in foreign cur-
rency exchange rates.
30
Selected Quarterly Data (unaudited)
ELI LILLY AND COMPANY AND SUBSIDIARIES
(Dollars in millions, except per-share data)
2007
Fourth
Third
Second
First
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cost of sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Operating expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Acquired in-process research and development . . . . . . . . . .
Asset impairments, restructuring, and other
special charges . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other income—net. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Income before income taxes. . . . . . . . . . . . . . . . . . . . . . . . . . .
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Earnings per share—basic . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Earnings per share—diluted. . . . . . . . . . . . . . . . . . . . . . . . . . .
$5,189.6
1,272.8
2,709.4
89.0
$4,586.8
1,054.6
2,322.3
—
$4,631.0
998.9
2,379.1
328.1
$4,226.1
922.5
2,171.0
328.5
98.2
(32.1)
1,052.3
854.4
81.3
(49.8)
1,178.4
926.3
.78
.78
.85
.85
—
(1.8)
926.7
663.6
.61
.61
123.0
(38.3)
719.4
508.7
.47
.47
Dividends paid per share. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
.425
.425
.425
.425
Common stock closing prices
High. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Low . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
59.47
49.09
58.44
54.09
60.56
54.39
54.99
51.63
2006
Fourth
Third
Second
First
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cost of sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Operating expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Asset impairments, restructuring, and
other special charges . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other income—net. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Income before income taxes. . . . . . . . . . . . . . . . . . . . . . . . . . .
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Earnings per share—basic . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Earnings per share—diluted. . . . . . . . . . . . . . . . . . . . . . . . . . .
Dividends paid per share. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$4,245.3
1,019.0
2,168.8
$3,864.1
860.4
1,953.9
$3,866.9
860.6
2,012.7
$3,714.7
806.5
1,883.7
945.2
(102.7)
215.0
132.3
—
(56.0)
1,105.8
873.6
—
(46.9)
1,040.5
822.0
—
(32.2)
1,056.7
834.8
.12
.12
.40
.80
.80
.40
.76
.76
.40
.77
.77
.40
Common stock closing prices
High. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Low . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
58.25
51.35
57.32
54.26
55.27
50.41
58.86
54.98
Our common stock is listed on the New York, London, and Swiss stock exchanges.
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Selected Financial Data (unaudited)
ELI LILLY AND COMPANY AND SUBSIDIARIES
(Dollars in millions, except net sales per employee and per-share data)
20072
2006
2005
2004
2003
Operations
Net sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $18,633.5
4,248.8
Cost of sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
3,486.7
Research and development . . . . . . . . . . . . . . . . . . .
6,095.1
Marketing, selling, and administrative . . . . . . . . . .
Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
926.1
Income before income taxes and cumulative
effect of a change in accounting principle . . . . .
Income taxes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net income as a percent of sales . . . . . . . . . . . . . . .
Net income per share—diluted . . . . . . . . . . . . . . . .
Dividends declared per share. . . . . . . . . . . . . . . . . .
Weighted-average number of shares
outstanding—diluted (thousands) . . . . . . . . . . . . 1,090,750
3,876.8
923.8
2,953.0
15.8%
2.71
1.75
$15,691.0
3,546.5
3,129.3
4,889.8
707.4
$14,645.3
3,474.2
3,025.5
4,497.0
931.1
$13,857.9 $12,582.5
2,675.1
2,350.2
4,055.4
240.1
3,223.9
2,691.1
4,284.2
716.8
3,418.0
755.3
2,662.7
17.0%
2.45
1.63
2,717.5
715.9
1,979.61
13.5%
1.81
1.54
2,941.9
1,131.8
1,810.1
3,261.7
700.9
2,560.8
13.1%
1.66
1.45
20.4%
2.37
1.36
1,087,490
1,092,150
1,088,936 1,082,230
Financial Position
Current assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $12,256.9
5,268.3
Current liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Property and equipment—net . . . . . . . . . . . . . . . . .
8,575.1
Total assets. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26,787.8
4,593.5
Long-term debt . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Shareholders’ equity . . . . . . . . . . . . . . . . . . . . . . . . . 13,664.4
$ 9,694.4
5,085.5
8,152.3
21,955.4
3,494.4
10,980.7
$10,795.8 $12,835.8 $ 8,768.9
5,560.8
6,539.0
21,688.3
4,687.8
9,764.8
5,716.3
7,912.5
24,580.8
5,763.5
10,791.9
7,593.7
7,550.9
24,867.0
4,491.9
10,919.9
S
L
A
I
C
N
A
N
I
F
Supplementary Data
Return on shareholders’ equity . . . . . . . . . . . . . . . .
Return on assets . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Capital expenditures . . . . . . . . . . . . . . . . . . . . . . . . . $ 1,082.4
Depreciation and amortization . . . . . . . . . . . . . . . . .
1,047.9
Effective tax rate . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net sales per employee. . . . . . . . . . . . . . . . . . . . . . . $ 459,000
40,600
Number of employees . . . . . . . . . . . . . . . . . . . . . . . .
41,700
Number of shareholders of record . . . . . . . . . . . . .
24.0%
12.2%
23.8%
24.5%
11.2%
18.2%
8.2%
17.5%
7.8%
28.4%
12.6%
$ 1,077.8
801.8
$ 1,298.1
726.4
22.1%
26.3%
$ 1,898.1 $ 1,706.6
548.5
597.5
38.5%
21.5%
$378,000
41,500
44,800
$344,000
42,600
50,800
$ 311,000
44,500
52,400
$280,000
45,000
54,600
1Refl ects the impact of a cumulative effect of a change in accounting principle in 2005 of $22.0 million, net of income taxes of $11.8 million. The diluted
earnings per share impact of this cumulative effect of a change in accounting principle was $.02. The net income per diluted share before the cumulative
effect of a change in accounting principle was $1.83. See Note 2 for additional information.
2Refl ects the ICOS acquisition, effective January 29, 2007. See Note 3 for additional information.
(cid:75)(cid:86)(cid:97)(cid:106)(cid:90)(cid:21)(cid:100)(cid:91)(cid:21)(cid:25)(cid:38)(cid:37)(cid:37)(cid:21)(cid:62)(cid:99)(cid:107)(cid:90)(cid:104)(cid:105)(cid:90)(cid:89)(cid:21)(cid:100)(cid:99)(cid:21)(cid:65)(cid:86)(cid:104)(cid:105)(cid:21)(cid:55)(cid:106)(cid:104)(cid:94)(cid:99)(cid:90)(cid:104)(cid:104)(cid:21)(cid:57)(cid:86)(cid:110)(cid:21)(cid:100)(cid:91)(cid:21)(cid:39)(cid:37)(cid:37)(cid:39)
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(cid:46)(cid:131)(cid:134)(cid:196)(cid:202)(cid:122)(cid:192)(cid:58)(cid:168)(cid:131)(cid:202)(cid:83)(cid:156)(cid:148)(cid:168)(cid:58)(cid:192)(cid:103)(cid:196)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:192)(cid:103)(cid:205)(cid:210)(cid:192)(cid:151)(cid:202)(cid:156)(cid:151)(cid:202)(cid:29)(cid:134)(cid:143)(cid:143)(cid:219)(cid:202)(cid:196)(cid:205)(cid:156)(cid:83)(cid:142)(cid:202)(cid:217)(cid:134)(cid:205)(cid:131)(cid:202)(cid:205)(cid:131)(cid:58)(cid:205)(cid:202)(cid:156)(cid:115)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)
(cid:45)(cid:205)(cid:58)(cid:151)(cid:94)(cid:58)(cid:192)(cid:94)(cid:202)(cid:65)(cid:202)(cid:42)(cid:156)(cid:156)(cid:192)(cid:189)(cid:196)(cid:202)(cid:117)(cid:223)(cid:223)(cid:202)(cid:45)(cid:205)(cid:156)(cid:83)(cid:142)(cid:202)(cid:22)(cid:151)(cid:94)(cid:103)(cid:218)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:156)(cid:210)(cid:192)(cid:202)(cid:168)(cid:103)(cid:103)(cid:192)(cid:202)(cid:122)(cid:192)(cid:156)(cid:210)(cid:168)(cid:202)(cid:115)(cid:156)(cid:192)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)
(cid:219)(cid:103)(cid:58)(cid:192)(cid:196)(cid:202)(cid:209)(cid:223)(cid:223)(cid:206)(cid:202)(cid:205)(cid:131)(cid:192)(cid:156)(cid:210)(cid:122)(cid:131)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:174)(cid:202)(cid:46)(cid:131)(cid:103)(cid:202)(cid:122)(cid:192)(cid:58)(cid:168)(cid:131)(cid:202)(cid:58)(cid:196)(cid:196)(cid:210)(cid:148)(cid:103)(cid:196)(cid:202)(cid:205)(cid:131)(cid:58)(cid:205)(cid:91)(cid:202)(cid:156)(cid:151)(cid:202)(cid:12)(cid:103)(cid:83)(cid:103)(cid:148)(cid:74)(cid:103)(cid:192)(cid:202)
(cid:206)(cid:163)(cid:91)(cid:202)(cid:209)(cid:223)(cid:223)(cid:209)(cid:91)(cid:202)(cid:58)(cid:202)(cid:168)(cid:103)(cid:192)(cid:196)(cid:156)(cid:151)(cid:202)(cid:134)(cid:151)(cid:216)(cid:103)(cid:196)(cid:205)(cid:103)(cid:94)(cid:202)(cid:100)(cid:163)(cid:223)(cid:223)(cid:202)(cid:103)(cid:58)(cid:83)(cid:131)(cid:202)(cid:134)(cid:151)(cid:202)(cid:29)(cid:134)(cid:143)(cid:143)(cid:219)(cid:202)(cid:196)(cid:205)(cid:156)(cid:83)(cid:142)(cid:91)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:45)(cid:65)(cid:42)(cid:202)(cid:117)(cid:223)(cid:223)(cid:202)
(cid:45)(cid:205)(cid:156)(cid:83)(cid:142)(cid:202)(cid:22)(cid:151)(cid:94)(cid:103)(cid:218)(cid:91)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:168)(cid:103)(cid:103)(cid:192)(cid:202)(cid:122)(cid:192)(cid:156)(cid:210)(cid:168)(cid:189)(cid:196)(cid:202)(cid:83)(cid:156)(cid:148)(cid:148)(cid:156)(cid:151)(cid:202)(cid:196)(cid:205)(cid:156)(cid:83)(cid:142)(cid:174)(cid:202)(cid:46)(cid:131)(cid:103)(cid:202)(cid:122)(cid:192)(cid:58)(cid:168)(cid:131)(cid:202)
(cid:148)(cid:103)(cid:58)(cid:196)(cid:210)(cid:192)(cid:103)(cid:196)(cid:202)(cid:205)(cid:156)(cid:205)(cid:58)(cid:143)(cid:202)(cid:196)(cid:131)(cid:58)(cid:192)(cid:103)(cid:131)(cid:156)(cid:143)(cid:94)(cid:103)(cid:192)(cid:202)(cid:192)(cid:103)(cid:205)(cid:210)(cid:192)(cid:151)(cid:91)(cid:202)(cid:217)(cid:131)(cid:134)(cid:83)(cid:131)(cid:202)(cid:205)(cid:58)(cid:142)(cid:103)(cid:196)(cid:202)(cid:134)(cid:151)(cid:205)(cid:156)(cid:202)(cid:58)(cid:83)(cid:83)(cid:156)(cid:210)(cid:151)(cid:205)(cid:202)
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(cid:74)(cid:219)(cid:202)(cid:58)(cid:202)(cid:83)(cid:156)(cid:148)(cid:168)(cid:58)(cid:151)(cid:219)(cid:202)(cid:58)(cid:192)(cid:103)(cid:202)(cid:192)(cid:103)(cid:134)(cid:151)(cid:216)(cid:103)(cid:196)(cid:205)(cid:103)(cid:94)(cid:202)(cid:134)(cid:151)(cid:202)(cid:205)(cid:131)(cid:58)(cid:205)(cid:202)(cid:83)(cid:156)(cid:148)(cid:168)(cid:58)(cid:151)(cid:219)(cid:189)(cid:196)(cid:202)(cid:196)(cid:205)(cid:156)(cid:83)(cid:142)(cid:174)
(cid:71)(cid:53)(cid:103)(cid:202)(cid:83)(cid:156)(cid:151)(cid:196)(cid:205)(cid:192)(cid:210)(cid:83)(cid:205)(cid:103)(cid:94)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:168)(cid:103)(cid:103)(cid:192)(cid:202)(cid:122)(cid:192)(cid:156)(cid:210)(cid:168)(cid:202)(cid:58)(cid:196)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:134)(cid:151)(cid:94)(cid:210)(cid:196)(cid:205)(cid:192)(cid:219)(cid:202)(cid:134)(cid:151)(cid:94)(cid:103)(cid:218)(cid:202)(cid:115)(cid:156)(cid:192)(cid:202)(cid:205)(cid:131)(cid:134)(cid:196)(cid:202)
(cid:122)(cid:192)(cid:58)(cid:168)(cid:131)(cid:174)(cid:202)(cid:22)(cid:205)(cid:202)(cid:83)(cid:156)(cid:148)(cid:168)(cid:192)(cid:134)(cid:196)(cid:103)(cid:196)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:151)(cid:134)(cid:151)(cid:103)(cid:202)(cid:83)(cid:156)(cid:148)(cid:168)(cid:58)(cid:151)(cid:134)(cid:103)(cid:196)(cid:202)(cid:134)(cid:151)(cid:202)(cid:205)(cid:131)(cid:103)(cid:202)(cid:168)(cid:131)(cid:58)(cid:192)(cid:148)(cid:58)(cid:83)(cid:103)(cid:210)(cid:205)(cid:134)(cid:83)(cid:58)(cid:143)(cid:202)
(cid:134)(cid:151)(cid:94)(cid:210)(cid:196)(cid:205)(cid:192)(cid:219)(cid:202)(cid:205)(cid:131)(cid:58)(cid:205)(cid:202)(cid:217)(cid:103)(cid:202)(cid:210)(cid:196)(cid:103)(cid:94)(cid:202)(cid:205)(cid:156)(cid:202)(cid:74)(cid:103)(cid:151)(cid:83)(cid:131)(cid:148)(cid:58)(cid:192)(cid:142)(cid:202)(cid:209)(cid:223)(cid:223)(cid:199)(cid:202)(cid:83)(cid:156)(cid:148)(cid:168)(cid:103)(cid:151)(cid:196)(cid:58)(cid:205)(cid:134)(cid:156)(cid:151)(cid:202)(cid:156)(cid:115)(cid:202)
(cid:103)(cid:218)(cid:103)(cid:83)(cid:210)(cid:205)(cid:134)(cid:216)(cid:103)(cid:202)(cid:156)(cid:115)(cid:115)(cid:134)(cid:83)(cid:103)(cid:192)(cid:196)(cid:90)(cid:202)(cid:1)(cid:74)(cid:74)(cid:156)(cid:205)(cid:205)(cid:202)(cid:29)(cid:58)(cid:74)(cid:156)(cid:192)(cid:58)(cid:205)(cid:156)(cid:192)(cid:134)(cid:103)(cid:196)(cid:198)(cid:202)(cid:1)(cid:148)(cid:122)(cid:103)(cid:151)(cid:202)(cid:22)(cid:151)(cid:83)(cid:174)(cid:198)(cid:202)(cid:9)(cid:192)(cid:134)(cid:196)(cid:205)(cid:156)(cid:143)(cid:133)(cid:202)
(cid:30)(cid:219)(cid:103)(cid:192)(cid:196)(cid:202)(cid:45)(cid:181)(cid:210)(cid:134)(cid:74)(cid:74)(cid:202)(cid:10)(cid:156)(cid:148)(cid:168)(cid:58)(cid:151)(cid:219)(cid:198)(cid:202)(cid:20)(cid:143)(cid:58)(cid:218)(cid:156)(cid:45)(cid:148)(cid:134)(cid:205)(cid:131)(cid:28)(cid:143)(cid:134)(cid:151)(cid:103)(cid:202)(cid:42)(cid:143)(cid:83)(cid:198)(cid:202)(cid:27)(cid:156)(cid:131)(cid:151)(cid:196)(cid:156)(cid:151)(cid:202)(cid:65)(cid:202)
(cid:27)(cid:156)(cid:131)(cid:151)(cid:196)(cid:156)(cid:151)(cid:198)(cid:202)(cid:30)(cid:103)(cid:192)(cid:83)(cid:142)(cid:202)(cid:65)(cid:202)(cid:10)(cid:156)(cid:174)(cid:91)(cid:202)(cid:22)(cid:151)(cid:83)(cid:174)(cid:198)(cid:202)(cid:42)(cid:115)(cid:134)(cid:222)(cid:103)(cid:192)(cid:202)(cid:22)(cid:151)(cid:83)(cid:174)(cid:198)(cid:202)(cid:45)(cid:83)(cid:131)(cid:103)(cid:192)(cid:134)(cid:151)(cid:122)(cid:133)(cid:42)(cid:143)(cid:156)(cid:210)(cid:122)(cid:131)(cid:202)
(cid:10)(cid:156)(cid:192)(cid:168)(cid:156)(cid:192)(cid:58)(cid:205)(cid:134)(cid:156)(cid:151)(cid:198)(cid:202)(cid:58)(cid:151)(cid:94)(cid:202)(cid:53)(cid:219)(cid:103)(cid:205)(cid:131)(cid:174)(cid:202)(cid:202)
(cid:25)(cid:39)(cid:37)(cid:37)
(cid:25)(cid:38)(cid:46)(cid:37)
(cid:25)(cid:38)(cid:45)(cid:37)
(cid:25)(cid:38)(cid:44)(cid:37)
(cid:25)(cid:38)(cid:43)(cid:37)
(cid:25)(cid:38)(cid:42)(cid:37)
(cid:25)(cid:38)(cid:41)(cid:37)
(cid:25)(cid:38)(cid:40)(cid:37)
(cid:25)(cid:38)(cid:39)(cid:37)
(cid:25)(cid:38)(cid:38)(cid:37)
(cid:25)(cid:38)(cid:37)(cid:37)
(cid:25)(cid:46)(cid:37)
(cid:65)(cid:94)(cid:97)(cid:97)(cid:110)(cid:21)
(cid:72)(cid:27)(cid:69)(cid:21)(cid:42)(cid:37)(cid:37)(cid:21)
(cid:69)(cid:90)(cid:90)(cid:103)(cid:21)(cid:60)(cid:103)(cid:100)(cid:106)(cid:101)
(cid:38)(cid:39)(cid:36)(cid:37)(cid:39)(cid:21)
(cid:38)(cid:39)(cid:36)(cid:37)(cid:40)(cid:21)
(cid:38)(cid:39)(cid:36)(cid:37)(cid:41)(cid:21)
(cid:38)(cid:39)(cid:36)(cid:37)(cid:42)(cid:21)
(cid:38)(cid:39)(cid:36)(cid:37)(cid:43)(cid:21)
(cid:38)(cid:39)(cid:36)(cid:37)(cid:44)
32
Eli Lilly
and
Company
S&P
500
Custom
Peer
Group
Date
12/02
$100.00
$100.00
$100.00
12/03
$113.11
$128.63
$111.25
12/04
$93.35
$142.59
$107.81
12/05
$95.71
$149.58
$107.90
12/06
$90.72
$173.15
$122.21
12/07
$95.87
$182.64
$124.15
F
I
N
A
N
C
I
A
L
S
Notes to Consolidated Financial Statements
ELI LILLY AND COMPANY AND SUBSIDIARIES
(Dollars in millions, except per-share data)
Note 1: Summary of Signifi cant Accounting Policies
Basis of presentation: The accompanying consolidated fi nancial statements have been prepared in accordance
with accounting practices generally accepted in the United States (GAAP). The accounts of all wholly owned and
majority-owned subsidiaries are included in the consolidated fi nancial statements. Where our ownership of con-
solidated subsidiaries is less than 100 percent, the outside shareholders’ interests are refl ected in other noncur-
rent liabilities. All intercompany balances and transactions have been eliminated.
The preparation of fi nancial statements in conformity with GAAP requires management to make estimates
and assumptions that affect the reported amounts of assets, liabilities, revenues, expenses, and related disclo-
sures at the date of the fi nancial statements and during the reporting period. Actual results could differ from
those estimates.
All per-share amounts, unless otherwise noted in the footnotes, are presented on a diluted basis, that is,
based on the weighted-average number of outstanding common shares plus the effect of dilutive stock options and
other incremental shares.
Cash equivalents: We consider all highly liquid investments, with a maturity of three months or less, to be cash
equivalents. The cost of these investments approximates fair value. If items meeting this defi nition are part of a
larger investment pool, they are classifi ed consistent with the classifi cation of the pool.
Inventories: We state all inventories at the lower of cost or market. We use the last-in, fi rst-out (LIFO) method for
substantially all our inventories located in the continental United States, or approximately 39 percent of our total
inventories. Other inventories are valued by the fi rst-in, fi rst-out (FIFO) method. FIFO cost approximates current
replacement cost. Inventories at December 31 consisted of the following:
Finished products . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Work in process . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Raw materials and supplies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Reduction to LIFO cost . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 653.4
1,803.0
202.7
2,659.1
(135.4)
$2,523.7
$ 644.5
1,551.5
187.0
2,383.0
(112.7)
$2,270.3
2007
2006
Investments: Substantially all debt and marketable equity securities are classifi ed as available-for-sale. Avail-
able-for-sale securities are carried at fair value with the unrealized gains and losses, net of tax, reported in other
comprehensive income. Unrealized losses considered to be other-than-temporary are recognized in earnings.
Factors we consider in making this evaluation include company-specifi c drivers of the decrease in stock price, sta-
tus of projects in development, near-term prospects of the issuer, the length of time the value has been depressed,
and the fi nancial condition of the industry. We do not evaluate cost-method investments for impairment unless
there is an indicator of impairment. We review these investments for indicators of impairment on a regular basis.
Realized gains and losses on sales of available-for-sale securities are computed based upon specifi c identifi ca-
tion of the initial cost adjusted for any other-than-temporary declines in fair value. Investments in companies over
which we have signifi cant infl uence but not a controlling interest are accounted for using the equity method with
our share of earnings or losses reported in other income—net. We own no investments that are considered to be
trading securities.
Risk-management instruments: Our derivative activities are initiated within the guidelines of documented corporate
risk-management policies and do not create additional risk because gains and losses on derivative contracts offset
losses and gains on the assets, liabilities, and transactions being hedged. As derivative contracts are initiated, we
designate the instruments individually as either a fair value hedge or a cash fl ow hedge. Management reviews the
correlation and effectiveness of our derivatives on a quarterly basis.
For derivative contracts that are designated and qualify as fair value hedges, the derivative instrument is
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marked to market with gains and losses recognized currently in income to offset the respective losses and gains
recognized on the underlying exposure. For derivative contracts that are designated and qualify as cash fl ow hedg-
es, the effective portion of gains and losses on these contracts is reported as a component of other comprehensive
income and reclassifi ed into earnings in the same period the hedged transaction affects earnings. Hedge inef-
fectiveness is immediately recognized in earnings. Derivative contracts that are not designated as hedging instru-
ments are recorded at fair value with the gain or loss recognized in current earnings during the period of change.
We enter into foreign currency forward and option contracts to reduce the effect of fl uctuating currency ex-
change rates (principally the euro, the British pound, and the Japanese yen). Foreign currency derivatives used for
hedging are put in place using the same or like currencies and duration as the underlying exposures. Forward con-
tracts are principally used to manage exposures arising from subsidiary trade and loan payables and receivables
denominated in foreign currencies. These contracts are recorded at fair value with the gain or loss recognized in
other income. The purchased option contracts are used to hedge anticipated foreign currency transactions, pri-
marily intercompany inventory activities expected to occur within the next year. These contracts are designated as
cash fl ow hedges of those future transactions and the impact on earnings is included in cost of sales. We may enter
into foreign currency forward contracts and currency swaps as fair value hedges of fi rm commitments. Forward
and option contracts generally have maturities not exceeding 12 months.
In the normal course of business, our operations are exposed to fl uctuations in interest rates. These fl uctuations
can vary the costs of fi nancing, investing, and operating. We address a portion of these risks through a controlled
program of risk management that includes the use of derivative fi nancial instruments. The objective of controlling
these risks is to limit the impact of fl uctuations in interest rates on earnings. Our primary interest rate risk exposure
results from changes in short-term U.S. dollar interest rates. In an effort to manage interest rate exposures, we
strive to achieve an acceptable balance between fi xed and fl oating rate debt and investment positions and may enter
into interest rate swaps or collars to help maintain that balance. Interest rate swaps or collars that convert our fi xed-
rate debt or investments to a fl oating rate are designated as fair value hedges of the underlying instruments. Interest
rate swaps or collars that convert fl oating rate debt or investments to a fi xed rate are designated as cash fl ow hedg-
es. Interest expense on the debt is adjusted to include the payments made or received under the swap agreements.
Goodwill and other intangibles: Goodwill is not amortized. All other intangibles arising from acquisitions and
research alliances have fi nite lives and are amortized over their estimated useful lives, ranging from 5 to 20 years,
using the straight-line method. The weighted-average amortization period for developed product technology is ap-
proximately 10 years. Amortization expense for 2007, 2006, and 2005 was $172.8 million, $7.6 million, and $5.4 mil-
lion before tax, respectively. The estimated amortization expense for the fi ve succeeding years approximates $180
million before tax, per year. Substantially all of the amortization expense is included in cost of sales. See Note 3 for
further discussion of goodwill and other intangibles acquired in 2007.
Goodwill and other intangible assets at December 31 were as follows:
Goodwill . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 745.7
2007
Developed product technology—gross . . . . . . . . . . . . . . . . . . . . . . . . .
Less accumulated amortization. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Developed product technology—net . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other intangibles—gross . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Less accumulated amortization. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other intangibles—net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1,767.5
(162.6)
1,604.9
142.8
(38.0)
104.8
2006
$ 73.8
—
—
—
89.2
(33.0)
56.2
Total intangibles—net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$2,455.4
$130.0
Goodwill and net other intangibles are reviewed to assess recoverability at least annually and when certain
impairment indicators are present. No material impairments occurred with respect to the carrying value of our
goodwill or other intangible assets in 2007, 2006, or 2005.
Property and equipment: Property and equipment is stated on the basis of cost. Provisions for depreciation of
buildings and equipment are computed generally by the straight-line method at rates based on their estimated
useful lives (12 to 50 years for buildings and 3 to 18 years for equipment). We review the carrying value of long-lived
34
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assets for potential impairment on a periodic basis and whenever events or changes in circumstances indicate the
carrying value of an asset may not be recoverable. Impairment is determined by comparing projected undiscount-
ed cash fl ows to be generated by the asset to its carrying value. If an impairment is identifi ed, a loss is recorded
equal to the excess of the asset’s net book value over its fair value, and the cost basis is adjusted.
At December 31, property and equipment consisted of the following:
Land . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Buildings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Equipment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Construction in progress . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Less allowances for depreciation . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 180.0
5,543.7
7,454.9
1,662.7
14,841.3
(6,266.2)
$8,575.1
$ 168.7
4,852.8
6,718.5
1,976.7
13,716.7
(5,564.4)
$8,152.3
2007
2006
Depreciation expense for 2007, 2006, and 2005 was $682.3 million, $627.4 million, and $577.2 million, respec-
tively. Approximately $95.3 million, $106.7 million, and $140.5 million of interest costs were capitalized as part of
property and equipment in 2007, 2006, and 2005, respectively. Total rental expense for all leases, including contin-
gent rentals (not material), amounted to approximately $294.2 million, $293.6 million, and $294.4 million for 2007,
2006, and 2005, respectively. Assets under capital leases included in property and equipment in the consolidated
balance sheets, capital lease obligations entered into, and future minimum rental commitments are not material.
Litigation and environmental liabilities: Litigation accruals and environmental liabilities and the related esti-
mated insurance recoverables are refl ected on a gross basis as liabilities and assets, respectively, on our consoli-
dated balance sheets. With respect to the product liability claims currently asserted against us, we have accrued
for our estimated exposures to the extent they are both probable and estimable based on the information available
to us. We accrue for certain product liability claims incurred but not fi led to the extent we can formulate a rea-
sonable estimate of their costs. We estimate these expenses based primarily on historical claims experience and
data regarding product usage. Legal defense costs expected to be incurred in connection with signifi cant product
liability loss contingencies are accrued when probable and reasonably estimable. A portion of the costs associated
with defending and disposing of these suits is covered by insurance. We record receivables for insurance-related
recoveries when it is probable they will be realized. These receivables are classifi ed as a reduction of the litigation
charges on the statement of income. We estimate insurance recoverables based on existing deductibles, cover-
age limits, our assessment of any defenses to coverage that might be raised by the carriers, and the existing and
projected future level of insolvencies among the insurance carriers.
Revenue recognition: We recognize revenue from sales of products at the time title of goods passes to the buyer
and the buyer assumes the risks and rewards of ownership. For more than 90 percent of our sales, this is at the
time products are shipped to the customer, typically a wholesale distributor or a major retail chain. The remaining
sales are recorded at the point of delivery. Provisions for discounts and rebates are established in the same period
the related sales are recorded.
We also generate income as a result of collaboration agreements. Revenue from copromotion services is
based upon net sales reported by our copromotion partners and, if applicable, the number of sales calls we per-
form. Initial fees we receive from the partnering of our compounds under development are amortized through the
expected product approval date. Initial fees received from out-licensing agreements that include both the sale of
marketing rights to our commercialized products and a related commitment to supply the products are gener-
ally recognized as net sales over the term of the supply agreement. We immediately recognize the full amount of
milestone payments due to us upon the achievement of the milestone event if the event is substantive, objectively
determinable, and represents an important point in the development life cycle of the pharmaceutical product.
Milestone payments earned by us are generally recorded in other income—net.
Research and development: We recognize as incurred the cost of directly acquiring assets to be used in the
research and development process that have not yet received regulatory approval for marketing and for which no
alternative future use has been identifi ed. Once the product has obtained regulatory approval, we capitalize the
milestones paid and amortize them over the period benefi ted. Milestones paid prior to regulatory approval of the
product are generally expensed when the event requiring payment of the milestone occurs.
35
Other income—net: Other income—net consisted of the following:
Interest expense . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Interest income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Joint venture income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 228.3
(215.3)
(11.0)
(124.0)
$(122.0)
$ 238.1
(261.9)
(96.3)
(117.7)
$(237.8)
$ 105.2
(212.1)
(11.1)
(196.2)
$(314.2)
2007
2006
2005
The joint venture income represents our share of the Lilly ICOS LLC joint venture results of operations, net of
income taxes. We acquired the outstanding ownership of the joint venture in January 2007 as a result of our acqui-
sition of ICOS. See Note 3 for further discussion.
Income taxes: Deferred taxes are recognized for the future tax effects of temporary differences between fi nancial
and income tax reporting based on enacted tax laws and rates. Federal income taxes are provided on the portion of
the income of foreign subsidiaries that is expected to be remitted to the United States and be taxable.
Effective January 1, 2007, we adopted the provisions of the Financial Accounting Standards Board (FASB)
Interpretation 48, Accounting for Uncertainty in Income Taxes (FIN 48). Pursuant to FIN 48, we must recognize the
tax benefi t from an uncertain tax position only if it is more likely than not that the tax position will be sustained on
examination by the taxing authorities, based on the technical merits of the position. The tax benefi ts recognized in
the fi nancial statements from such a position are measured based on the largest benefi t that has a greater than
50 percent likelihood of being realized upon ultimate resolution.
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Earnings per share: We calculate basic earnings per share based on the weighted-average number of outstanding
common shares and incremental shares. We calculate diluted earnings per share based on the weighted-average
number of outstanding common shares plus the effect of dilutive stock options and other incremental shares.
Stock-based compensation: We recognize the fair value of stock-based compensation as expense over the requi-
site service period of the individual grantees, which generally equals the vesting period. Under our policy all stock-
based awards are approved prior to the date of grant. The Compensation Committee of the Board of Directors
approves the value of the award and date of grant. Stock-based compensation that is awarded as part of our annual
equity grant is made on a specifi c grant date scheduled in advance.
Reclassifi cations: Certain reclassifi cations have been made to the December 31, 2006 and 2005 consolidated
fi nancial statements and accompanying notes to conform with the December 31, 2007 presentation.
Note 2: Implementation of New Financial Accounting Pronouncements
In December 2007, the Financial Accounting Standards Board (FASB) revised and issued Statement of Financial Ac-
counting Standard (SFAS) No. 141, Business Combinations (SFAS 141(R)). SFAS 141(R) changes how the acquisition
method is applied in accordance with SFAS 141. The primary revisions to this Statement require an acquirer in a
business combination to measure assets acquired, liabilities assumed, and any noncontrolling interest in the ac-
quiree at the acquisition date, at their fair values as of that date, with limited exceptions specifi ed in the Statement.
This Statement also requires the acquirer in a business combination achieved in stages to recognize the identifi -
able assets and liabilities, as well as the noncontrolling interest in the acquiree, at the full amounts of their fair
values (or other amounts determined in accordance with the Statement). Assets acquired and liabilities assumed
arising from contractual contingencies as of the acquisition date are to be measured at their acquisition-date fair
values, and assets or liabilities arising from all other contingencies as of the acquisition date are to be measured
at their acquisition-date fair value, only if it is more likely than not that they meet the defi nition of an asset or a li-
ability in FASB Concepts Statement No. 6, Elements of Financial Statements. This Statement signifi cantly amends
other Statements and authoritative guidance, including FASB Interpretation No. 4, Applicability of FASB Statement
No. 2 to Business Combinations Accounted for by the Purchase Method, and now requires the capitalization of re-
search and development assets acquired in a business combination at their acquisition-date fair values, separately
from goodwill. SFAS No. 109, Accounting for Income Taxes, was also amended by this Statement to require the ac-
quirer to recognize changes in the amount of its deferred tax benefi ts that are recognizable because of a business
36
combination either in income from continuing operations in the period of the combination or directly in contributed
capital, depending on the circumstances. This Statement is effective for us for business combinations for which the
acquisition date is on or after January 1, 2009.
In December 2007, in conjunction with SFAS 141(R), the FASB issued SFAS No. 160, Accounting for Noncontrol-
ling Interests. This Statement amends Accounting Research Bulletin No. 51, Consolidated Financial Statements
(ARB 51), by requiring companies to report a noncontrolling interest in a subsidiary as equity in its consolidated
fi nancial statements. Disclosure of the amounts of consolidated net income attributable to the parent and the
noncontrolling interest will be required. This Statement also clarifi es that transactions that result in a change in a
parent’s ownership interest in a subsidiary that do not result in deconsolidation will be treated as equity transac-
tions, while a gain or loss will be recognized by the parent when a subsidiary is deconsolidated. This Statement is
effective for us January 1, 2009, and we do not anticipate the implementation to be material to our consolidated
fi nancial position or results of operations.
In December 2007, the FASB ratifi ed the consensus reached by the Emerging Issues Task Force (EITF) on Issue
No. 07-1 (EITF 07-1), Accounting for Collaborative Arrangements. EITF 07-1 defi nes collaborative arrangements
and establishes reporting requirements for transactions between participants in a collaborative arrangement and
between participants in the arrangement and third parties. This Issue is effective for us beginning January 1, 2009
and will be applied retrospectively to all prior periods presented for all collaborative arrangements existing as of
the effective date. While we have not yet completed our analysis, we do not anticipate the implementation of this
Issue to be material to our consolidated fi nancial position or results of operations.
In June 2007, the FASB ratifi ed the consensus reached by the EITF on Issue No. 07-3 (EITF 07-3), Accounting
for Nonrefundable Advance Payments for Goods or Services Received for Use in Future Research and Development
Activities. Pursuant to EITF 07-3, nonrefundable advance payments for goods or services that will be used or ren-
dered for future research and development activities should be deferred and capitalized. Such amounts should be
recognized as an expense when the related goods are delivered or services are performed, or when the goods or
services are no longer expected to be received. This Issue is effective for us beginning January 1, 2008, and is to be
applied prospectively for contracts entered into on or after the effective date. We do not anticipate the implementa-
tion of this Issue to be material to our consolidated fi nancial position or results of operations.
In February 2007, the FASB issued SFAS No. 159, The Fair Value Option for Financial Assets and Financial Lia-
bilities. SFAS 159 permits entities to choose to measure many fi nancial instruments and certain other items at fair
value. The objective is to improve fi nancial reporting by providing entities with the opportunity to mitigate volatility
in reported earnings caused by measuring related assets and liabilities differently without having to apply complex
hedge accounting provisions. This Statement is effective for us beginning January 1, 2008, if adopted; however, we
do not anticipate adopting this Statement.
We adopted the provisions of FASB Interpretation (FIN) No. 48, Accounting for Uncertainty in Income Taxes,
on January 1, 2007. FIN 48 prescribes a recognition threshold and measurement attribute for the fi nancial state-
ment recognition and measurement of a tax position taken or expected to be taken in a tax return. See Note 11 for
further discussion of the impact of adopting this Interpretation.
In September 2006, the FASB issued SFAS No. 157, Fair Value Measurements. SFAS 157 defi nes fair value, es-
tablishes a framework for measuring fair value in GAAP, and expands disclosures about fair value measurements.
This Statement is effective for us beginning January 1, 2008, and applies to interim periods. We do not anticipate the
implementation of this Statement will be material to our consolidated fi nancial position or results of operations.
In 2005, the FASB issued FIN 47, Accounting for Conditional Asset Retirement Obligations, an interpretation of
FASB Statement No. 143. FIN 47 requires us to record the fair value of a liability for conditional asset retirement
obligations in the period in which it is incurred, which is adjusted to its present value each subsequent period. In
addition, we are required to capitalize a corresponding amount by increasing the carrying amount of the related
long-lived asset, which is depreciated over the useful life of the related long-lived asset. The adoption of FIN 47
on December 31, 2005 resulted in a cumulative effect of a change in accounting principle of $22.0 million, net of
income taxes of $11.8 million.
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Note 3: Acquisitions
ICOS Corporation Acquisition
On January 29, 2007, we acquired all of the outstanding common stock of ICOS Corporation (ICOS), our partner in
the Lilly ICOS LLC joint venture for the manufacture and sales of Cialis for the treatment of erectile dysfunction.
The acquisition brings the full value of Cialis to us and enables us to realize operational effi ciencies in the further
development, marketing, and selling of this product. Under the terms of the agreement, each outstanding share of
ICOS common stock was redeemed for $34 in cash for an aggregate purchase price of approximately $2.3 billion,
which was fi nanced through borrowings.
The acquisition has been accounted for as a business combination under the purchase method of accounting.
Under the purchase method of accounting, the assets acquired and liabilities assumed from ICOS are recorded at
their respective fair values as of the acquisition date in our consolidated fi nancial statements. The excess of the
purchase price over the fair value of the acquired net assets has been recorded as goodwill in the amount of
$646.7 million. No portion of this goodwill is expected to be deductible for tax purposes. ICOS’s results of opera-
tions are included in our consolidated fi nancial statements from the date of acquisition.
We have determined the following estimated fair values for the assets purchased and liabilities assumed as of
the date of acquisition. The determination of estimated fair value requires management to make signifi cant esti-
mates and assumptions.
Estimated Fair Value at January 29, 2007
Cash and short-term investments. . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Developed product technology (Cialis)1 . . . . . . . . . . . . . . . . . . . . . . . .
Acquired in-process research and development . . . . . . . . . . . . . . . . .
Tax benefi t of net operating losses . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Goodwill . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other assets and liabilities—net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Deferred taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Long-term debt assumed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total estimated purchase price . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 197.7
1,659.9
303.5
404.1
646.7
(32.1)
(583.5)
(275.6)
$2,320.7
1The intangible asset will be amortized over the remaining expected patent lives of Cialis in each country, which range from 2015
to 2017.
The acquired in-process research and development (IPR&D) represents compounds currently under develop-
ment that have not yet achieved regulatory approval for marketing. New indications for and formulations of the Cialis
compound in clinical testing at the time of the acquisition represented approximately 48 percent of the estimated fair
value of the IPR&D. The remaining value of IPR&D represents several other products in development, with no one
asset comprising a signifi cant portion of this value. In accordance with FIN 4, Applicability of FASB Statement No. 2 to
Business Combinations Accounted for by the Purchase Method, these IPR&D intangible assets totaling $303.5 million
have been written off by a charge to income immediately subsequent to the acquisition because the compounds do
not have any alternative future use. This charge is not deductible for tax purposes. The ongoing activity with respect
to each of these compounds under development is not material to our research and development expenses.
There are several methods that can be used to determine the estimated fair value of the acquired IPR&D. We
utilized the “income method,” which applies a probability weighting to the estimated future net cash fl ows that
are derived from projected sales revenues and estimated costs. These projections are based on factors such as
relevant market size, patent protection, historical pricing of similar products, and expected industry trends. The
estimated future net cash fl ows are then discounted to the present value using an appropriate discount rate. This
analysis is performed for each project independently. The discount rate we used in valuing the acquired IPR&D
projects was 20 percent.
Other Acquisitions
During the second quarter of 2007, we acquired all of the outstanding stock of both Hypnion, Inc. (Hypnion), a
privately held neuroscience drug discovery company focused on sleep disorders, and Ivy Animal Health, Inc. (Ivy),
a privately held applied research and pharmaceutical product development company focused on the animal health
industry, for $445.0 million in cash. The ongoing activities with respect to these companies’ products in develop-
ment are not material to our research and development expenses. The results of operations are included in our
38
consolidated fi nancial statements from the respective dates of acquisition.
The acquisition of Hypnion provides us with a broader and more substantive presence in the area of sleep
disorder research and ownership of HY10275, a novel Phase II compound with a dual mechanism of action aimed
at promoting better sleep onset and sleep maintenance. This was Hypnion’s only signifi cant asset. For this acquisi-
tion, we recorded a charge of $291.1 million, representing the estimated fair value of the acquired compound, to
acquired IPR&D in the second quarter of 2007 because the development-stage compound acquired did not have
any alternative future use. This charge was not deductible for tax purposes. Because Hypnion was a development-
stage company, the transaction was accounted for as an acquisition of assets rather than as a business combina-
tion and, therefore, goodwill was not recorded.
The acquisition of Ivy provides us with products that complement those of our animal health product line. This
acquisition has been accounted for as a business combination under the purchase method of accounting. We have
allocated $88.7 million of the purchase price to other identifi able intangible assets, primarily related to marketed
products, $37.0 million to acquired IPR&D, and $25.0 million to goodwill. The IPR&D represents products in devel-
opment that are not yet approved for marketing and have no alternative future use. Accordingly, the $37.0 mil-
lion allocated to acquired IPR&D was expensed immediately subsequent to the acquisition. The other identifi able
intangible assets will be amortized over their estimated remaining useful lives of 10 to 20 years. Goodwill resulting
from this acquisition has been fully allocated to the animal health business segment. The amount allocated to each
of the intangible assets acquired, including goodwill, is expected to be deductible for tax purposes.
Product Acquisitions
In October 2007, we entered into an agreement with Glenmark Pharmaceuticals Limited India whereby we ac-
quired the rights to a portfolio of transient receptor potential vanilloid sub-family 1 (TRPV1) antagonist molecules,
including a clinical-phase compound. The compound is currently in early clinical phase development as a potential
next-generation treatment for various pain conditions, including osteoarthritic pain, and had no alternative future
use. As with many development-phase compounds, launch of the product, if approved, was not expected in the
near term. Our charge for acquired IPR&D was $45.0 million, is deductible for tax purposes, and was included as
expense in the fourth quarter of 2007.
In October 2007, we entered into a global strategic alliance with MacroGenics, Inc. (MacroGenics) to develop
and commercialize teplizumab, a humanized anti-CD3 monoclonal antibody, as well as other potential next-gen-
eration anti-CD3 molecules for use in the treatment of autoimmune diseases. As part of the arrangement, we
acquired the exclusive rights to the molecule, which was in the development stage (Phase II/III clinical trial for
individuals with recent-onset type 1 diabetes) and had no alternative future use. As with many development-phase
compounds, launch of the product, if approved, was not expected in the near term. Our charge for acquired IPR&D
was $44.0 million, is deductible for tax purposes, and was included as expense in the fourth quarter of 2007.
In January 2007, we entered into an agreement with OSI Pharmaceuticals, Inc. to acquire the rights to its
compound for the treatment of type 2 diabetes. At the inception of this agreement, this compound was in the
development stage (Phase I clinical trials) and had no alternative future use. As with many development-phase
compounds, launch of the product, if approved, was not expected in the near term. Our charge for acquired IPR&D
related to this arrangement was $25.0 million, was included as expense in the fi rst quarter of 2007, and is deduct-
ible for tax purposes.
In December 2007, we entered into an agreement with BioMS Medical Corp. to acquire the rights to its com-
pound for the treatment of multiple sclerosis. This agreement was contingent upon clearance under the Hart-
Scott-Rodino Anti-Trust Improvements Act and became effective after clearance was received in January 2008.
This compound is in the development stage (Phase III clinical trials) and has no alternative future use. As with
many development-phase compounds, launch of the product, if approved, was not expected in the near term. Our
charge for acquired IPR&D related to this arrangement was $87.0 million, is deductible for tax purposes, and will
be included as expense in the fi rst quarter of 2008.
In connection with these arrangements, our partners are generally entitled to future milestones and royalties
based on sales should these products be approved for commercialization.
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Note 4: Asset Impairments, Restructuring, and Other Special Charges
The components of the charges included in asset impairments, restructuring, and other special charges in our
consolidated statements of income are described below.
Asset Impairments and Related Restructuring and Other Charges
We incurred asset impairment, restructuring, and other special charges of $67.6 million in the fourth quarter of
2007. These charges were a result of decisions approved by management in the fourth quarter as well as previ-
ously announced strategic decisions. Components of this charge include non-cash charges of $42.5 million for
the write-down of impaired assets, all of which have no future use, and other charges of $25.1 million, primar-
ily related to additional severance and environmental cleanup charges related to previously announced strategic
decisions. The impairment charges are necessary to adjust the carrying value of the assets to fair value. These
restructuring activities were substantially complete at December 31, 2007.
In connection with previously announced strategic decisions, we recorded asset impairment, restructuring,
and other special charges of $123.0 million in the fi rst quarter of 2007. These charges primarily relate to a volun-
tary severance program at one of our U.S. plants and other costs related to this action as well as management
actions taken in the fourth quarter of 2006 as described below. The component of this charge related to the non-
cash asset impairment was $67.6 million, and was necessary to adjust the carrying value of the assets to fair
value. These restructuring activities were substantially complete at December 31, 2007.
In the fourth quarter of 2006, management approved plans to close two research and development facilities
and one production facility outside the U.S. Management also made the decision to stop construction of a planned
insulin manufacturing plant in the U.S. in an effort to increase productivity in research and development opera-
tions and to reduce excess manufacturing capacity. These decisions, as well as other strategic changes, resulted
in non-cash charges of $308.8 million for the write-down of certain impaired assets, substantially all of which
have no future use, and other charges of $141.5 million, primarily related to severance and contract termination
payments. The impairment charges were necessary to adjust the carrying value of the assets to fair value. These
restructuring activities were substantially complete at December 31, 2007.
In December 2005, management approved, as part of our ongoing efforts to increase productivity and reduce
our cost structure, decisions that resulted in non-cash charges of $154.6 million for the write-down of certain im-
paired assets, and other charges of $17.3 million, primarily related to contract termination payments. The impaired
assets, which had no future use, included manufacturing buildings and equipment no longer needed to supply pro-
jected capacity requirements, as well as obsolete research and development equipment. The impairment charges
were necessary to adjust the carrying value of the assets to fair value.
Product Liability and Other Special Charges
As a result of our product liability exposures, the substantial majority of which were related to Zyprexa, we re-
corded net pretax charges of $111.9 million, $494.9 million, and $1.07 billion in 2007, 2006, and 2005, respectively.
These charges, which are net of anticipated insurance recoveries, include the costs of product liability settlements
and related defense costs, reserves for product liability exposures and defense costs regarding known product
liability claims, and expected future claims to the extent we could formulate a reasonable estimate of the probable
number and cost of the claims. See Note 13 for further discussion.
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Note 5: Financial Instruments and Investments
Financial instruments that potentially subject us to credit risk consist principally of trade receivables and interest-
bearing investments. Wholesale distributors of life-sciences products and managed care organizations account
for a substantial portion of trade receivables; collateral is generally not required. The risk associated with this
concentration is mitigated by our ongoing credit review procedures and insurance. We place substantially all our
interest-bearing investments with major fi nancial institutions, in U.S. government securities, or with top-rated
corporate issuers. At December 31, 2007, our investments in debt securities were comprised of 40 percent asset-
backed securities, 23 percent corporate securities, and 37 percent U.S. government securities. In accordance with
documented corporate policies, we limit the amount of credit exposure to any one fi nancial institution or corporate
issuer. We are exposed to credit-related losses in the event of nonperformance by counterparties to fi nancial in-
struments but do not expect any counterparties to fail to meet their obligations given their high credit ratings.
Fair Value of Financial Instruments
A summary of our outstanding fi nancial instruments and other investments at December 31 follows:
2007
2006
Carrying Amount
Fair Value
Carrying Amount
Fair Value
Short-term investments
Debt securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 1,610.7
$ 1,610.7
$ 781.7
$ 781.7
Noncurrent investments
Marketable equity . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 70.0
408.3
Debt securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
98.8
Equity method and other investments . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $ 577.1
$ 70.0
408.3
NA
$ 79.4
834.1
88.4
$ 1,001.9
$ 79.4
834.1
NA
Long-term debt, including current portion. . . . . . . . . . $(4,988.6)
$(5,056.9)
$(3,705.2)
$(3,682.7)
Risk-management instruments—assets . . . . . . . . . . .
23.6
23.6
19.7
19.7
We determine fair values based on quoted market values where available or discounted cash fl ow analyses
(principally long-term debt). The fair value of equity method and other investments is not readily available and dis-
closure is not required. Approximately $1.9 billion of our investments in debt securities mature within fi ve years.
A summary of the unrealized gains and losses (pretax) of our available-for-sale securities in other compre-
hensive income at December 31 follows:
Unrealized gross gains . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Unrealized gross losses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2007
$43.5
22.0
2006
$43.7
10.8
The net adjustment to unrealized gains and losses (net of tax) on available-for-sale securities increased
(decreased) other comprehensive income by $(5.4) million, $0.3 million, and $(4.6) million in 2007, 2006, and 2005,
respectively. Activity related to our available-for-sale investment portfolio was as follows:
Proceeds from sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Realized gross gains on sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Realized gross losses on sales . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$1,212.1
21.4
6.1
$2,848.4
63.5
9.0
$2,048.6
25.6
7.1
2007
2006
2005
During the years ended December 31, 2007, 2006, and 2005, net losses related to ineffectiveness and net loss-
es related to the portion of our risk-management hedging instruments, fair value and cash fl ow hedges, excluded
from the assessment of effectiveness were not material.
We expect to reclassify an estimated $21.3 million of pretax net losses on cash fl ow hedges of anticipated
foreign currency transactions and the variability in expected future interest payments on fl oating rate debt from
accumulated other comprehensive loss to earnings during 2008.
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Note 6: Borrowings
Long-term debt at December 31 consisted of the following:
2007
2006
4.50 to 7.13 percent notes (due 2012-2037) . . . . . . . . . . . . . . . . . . . . . .
2.90 percent notes (due 2008). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Floating rate extendible notes (due 2008) . . . . . . . . . . . . . . . . . . . . . .
Floating rate bonds (due 2037). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Private placement bonds (due 2007 and 2008). . . . . . . . . . . . . . . . . . .
6.55 percent ESOP debentures (due 2017) . . . . . . . . . . . . . . . . . . . . . .
Other, including capitalized leases . . . . . . . . . . . . . . . . . . . . . . . . . . . .
SFAS 133 fair value adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Less current portion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$3,987.4
300.0
—
400.0
72.1
90.6
59.3
79.2
4,988.6
(395.1)
$4,593.5
$1,487.4
300.0
1,000.0
400.0
266.3
91.6
109.9
50.0
3,705.2
(210.8)
$3,494.4
In March 2007, we issued $2.50 billion of fi xed-rate notes ($1.00 billion at 5.20 percent due in 2017; $700.0 mil-
lion at 5.50 percent due in 2027; and $800.0 million at 5.55 percent due in 2037).
In August 2005, Eli Lilly Services, Inc. (ELSI), our indirect wholly-owned fi nance subsidiary, issued $1.50 billion
of 13-month fl oating rate extendible notes. These notes paid interest at essentially a rate equivalent to LIBOR. We
repaid $500.0 million of the notes in December 2006 and the remaining $1.00 billion of the notes in March 2007.
The $400.0 million of fl oating rate bonds outstanding at December 31, 2007 are due in 2037 and have variable
interest rates at LIBOR plus our six-month credit spread, adjusted semiannually (total of 4.99 percent at December
31, 2007). The interest was to accumulate over the life of the bonds and be payable upon maturity. We had an option
to begin periodic interest payments at any time. We exercised this option in November 2006 and paid all previously
accrued interest on the bonds.
Principal and interest on the private placement bonds are due semiannually over the remaining terms of each
of these notes. In conjunction with these bonds, we entered into interest rate swap agreements with the same
fi nancial institution, which converts the fi xed rate into a variable rate of interest at essentially LIBOR over the term
of the bonds.
The 6.55 percent Employee Stock Ownership Plan (ESOP) debentures are obligations of the ESOP but are
shown on the consolidated balance sheet because we guarantee them. The principal and interest on the debt are
funded by contributions from us and by dividends received on certain shares held by the ESOP. Because of the am-
ortizing feature of the ESOP debt, bondholders will receive both interest and principal payments each quarter.
The aggregate amounts of maturities on long-term debt for the next fi ve years are as follows: 2008, $395.1 mil-
lion; 2009, $31.1 million; 2010, $16.7 million; 2011, $11.2 million; and 2012, $510.9 million.
At December 31, 2007 and 2006, short-term borrowings included $18.6 million and $8.6 million, respectively,
of notes payable to banks and commercial paper. At December 31, 2007, we have $1.24 billion of unused commit-
ted bank credit facilities, $1.20 billion of which backs our commercial paper program. Compensating balances
and commitment fees are not material, and there are no conditions that are probable of occurring under which the
lines may be withdrawn.
We have converted approximately 40 percent of all fi xed-rate debt to fl oating rates through the use of interest
rate swaps. The weighted-average effective borrowing rates based on debt obligations and interest rates at Decem-
ber 31, 2007 and 2006, including the effects of interest rate swaps for hedged debt obligations, were 5.47 percent
and 5.89 percent, respectively.
In 2007, 2006, and 2005, cash payments of interest on borrowings totaled $159.2 million, $305.7 million, and
$38.2 million, respectively, net of capitalized interest.
In accordance with the requirements of SFAS 133, the portion of our fi xed-rate debt obligations that is hedged
is refl ected in the consolidated balance sheets as an amount equal to the sum of the debt’s carrying value plus the
fair value adjustment representing changes in fair value of the hedged debt attributable to movements in market
interest rates subsequent to the inception of the hedge.
42
Note 7: Stock Plans
We recognize the fair value of stock-based compensation in net income. Stock-based compensation cost in the amount
of $282.0 million, $359.3 million, and $403.5 million was recognized in 2007, 2006, and 2005, respectively, as well as
related tax benefi ts of $96.4 million, $115.9 million, and $122.9 million, respectively. In 2007, our stock-based compen-
sation expense consisted primarily of performance awards (PAs), shareholder value awards (SVAs), and stock options.
In 2006 and 2005, our stock-based compensation expense consisted primarily of PAs and stock options. We recognize
the stock-based compensation expense over the requisite service period of the individual grantees, which generally
equals the vesting period. We provide newly issued shares and treasury stock to satisfy stock option exercises and for
the issuance of PA and SVA shares. We classify tax benefi ts resulting from tax deductions in excess of the compensation
cost recognized for exercised stock options as a fi nancing cash fl ow in the consolidated statements of cash fl ows.
At December 31, 2007, additional stock options, PAs, SVAs, or restricted stock grants may be granted under
the 2002 Lilly Stock Plan for not more than 46.6 million shares.
Performance Award Program
Performance awards (PAs) are granted to offi cers and management and are payable in shares of our common stock.
The number of PA shares actually issued, if any, varies depending on the achievement of certain pre-established
earnings-per-share targets over a one-year period. PA shares are accounted for at fair value based upon the closing
stock price on the date of grant and fully vest at the end of the fi scal year of the grant. The fair values of perfor-
mance awards granted in 2007, 2006, and 2005 were $54.23, $56.18, and $55.65, respectively. The number of shares
ultimately issued for the performance award program is dependent upon the earnings achieved during the vesting
period. Pursuant to this plan, approximately 2.3 million shares, 1.7 million shares, and 0.5 million shares were is-
sued in 2007, 2006, and 2005, respectively. Approximately 2.4 million shares are expected to be issued in 2008.
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Shareholder Value Award Program
In 2007, we implemented a shareholder value award (SVA) program, which replaced our stock option program.
SVAs are granted to offi cers and management and are payable in shares of common stock at the end of a three-
year period. The number of shares actually issued varies depending on our stock price at the end of the three-year
vesting period compared to pre-established target stock prices. We measure the fair value of the SVA unit on the
grant date using a Monte Carlo simulation model. The Monte Carlo simulation model utilizes multiple input vari-
ables that determine the probability of satisfying the market condition stipulated in the award grant and calculates
the fair value of the award. Expected volatilities utilized in the model are based on implied volatilities from traded
options on our stock, historical volatility of our stock price, and other factors. Similarly, the dividend yield is based
on historical experience and our estimate of future dividend yields. The risk-free interest rate is derived from the
U.S. Treasury yield curve in effect at the time of grant. The weighted-average fair values of the SVA units granted
during 2007 were $49.85 determined using the following assumptions:
2.75%
Expected dividend yield. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Risk-free interest rate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
4.81%–5.16%
Range of volatilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22.54%–23.90%
We granted approximately 970,000 SVA units in February 2007 as part of the annual total compensation award,
of which the majority remains outstanding at December 31, 2007. None of the SVA units are vested. The maximum
number of shares that could ultimately be issued upon vesting of the SVA units outstanding at December 31, 2007,
is 1.4 million. As of December 31, 2007, the total remaining unrecognized compensation cost related to nonvested
SVAs amounted to $34.0 million, which will be amortized over the weighted-average remaining requisite service
period of 25.5 months.
Stock Option Program
Stock options were granted in 2006 and 2005 to offi cers and management at exercise prices equal to the fair market
value of our stock price at the date of grant. No stock options were granted in 2007. Options fully vest three years
from the grant date and have a term of 10 years. We utilized a lattice-based option valuation model for estimating
the fair value of the stock options. The lattice model allows the use of a range of assumptions related to volatility,
risk-free interest rate, and employee exercise behavior. Expected volatilities utilized in the lattice model are based
on implied volatilities from traded options on our stock, historical volatility of our stock price, and other factors.
Similarly, the dividend yield is based on historical experience and our estimate of future dividend yields. The risk-free
43
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interest rate is derived from the U.S. Treasury yield curve in effect at the time of grant. The model incorporates exer-
cise and post-vesting forfeiture assumptions based on an analysis of historical data. The expected life of the 2006 and
2005 grants is derived from the output of the lattice model. The weighted-average fair values of the individual options
granted during 2006 and 2005 were $15.61 and $16.06, respectively, determined using the following assumptions:
Dividend yield . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Weighted-average volatility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Range of volatilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Risk-free interest rate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Weighted-average expected life. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2.0%
25.0%
24.8%–27.0%
4.6%–4.8%
7 years
2.0%
27.8%
27.6%–30.7%
2.5%–4.5%
7 years
2006
2005
Stock option activity during 2007 is summarized below:
Shares of
Common Stock
Attributable to Options
(in thousands)
Weighted-Average
Exercise
Price of Options
Weighted-Average
Remaining
Contractual Term
(in years)
Aggregate
Intrinsic Value
Outstanding at January 1, 2007 . . . . . . . . . . . . . . . .
Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Exercised . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Forfeited or expired . . . . . . . . . . . . . . . . . . . . . . . . . .
Outstanding at December 31, 2007 . . . . . . . . . . . . .
Exercisable at December 31, 2007. . . . . . . . . . . . . .
88,810
—
(283)
(7,378)
81,149
72,100
$69.38
—
53.83
67.85
69.57
71.15
4.15
3.73
$8.4
8.4
A summary of the status of nonvested options as of December 31, 2007, and changes during the year then
ended, is presented below:
Nonvested at January 1, 2007. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Granted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Vested . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Forfeited . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Nonvested at December 31, 2007. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Shares
(in thousands)
24,172
—
(14,668)
(455)
9,049
Weighted-Average
Grant Date
Fair Value
$22.32
—
26.03
19.08
16.47
The intrinsic value of options exercised during 2007, 2006, and 2005 amounted to $1.5 million, $40.8 mil-
lion, and $131.9 million, respectively. The total grant date fair value of options vested during 2007, 2006, and 2005
amounted to $381.8 million, $249.1 million, and $265.5 million, respectively. We received cash of $15.2 million,
$66.2 million, and $105.9 million from exercises of stock options during 2007, 2006, and 2005, respectively, and
recognized related tax benefi ts of $0.4 million, $11.3 million, and $36.8 million during those same years.
As of December 31, 2007, the total remaining unrecognized compensation cost related to nonvested stock op-
tions amounted to $23.8 million, which will be amortized over the weighted-average remaining requisite service
period of 12 months.
Note 8: Other Assets and Other Liabilities
Our other receivables include income tax receivable, insurance recoverables, interest receivable, and a variety of
other items. The increase in other receivables is primarily attributable to an increase in income tax receivable.
Our sundry assets include our capitalized computer software, estimated insurance recoveries from our prod-
uct litigation (Note 13), deferred tax assets (Note 11), and a variety of other items. The decrease in sundry assets is
primarily attributable to a decrease in product liability recoverables and a decrease in deferred tax assets.
Our other current liabilities include product litigation, other taxes, and a variety of other items. The decrease
in other current liabilities is caused primarily by a decrease in product litigation liabilities.
Our other noncurrent liabilities include product litigation, deferred income from our collaboration and out-
licensing arrangements, and a variety of other items. The decrease in other noncurrent liabilities is primarily
attributable to a decrease in product litigation liabilities.
44
Note 9: shareholders’ Equity
Changes in certain components of shareholders’ equity were as follows:
Additional
Paid-in
Capital
Retained
Earnings
Deferred
Costs—ESOP
Shares
(in thousands)
Amount
Common Stock in Treasury
Balance at January 1, 2005 . . . . . . . . . . . . . . . . . . . . $3,119 .4
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cash dividends declared per share: $1 .54 . . . . . . .
Retirement of treasury shares . . . . . . . . . . . . . . . . .
Purchase for treasury . . . . . . . . . . . . . . . . . . . . . . . .
Issuance of stock under employee stock plans . . .
Stock-based compensation . . . . . . . . . . . . . . . . . . .
ESOP transactions . . . . . . . . . . . . . . . . . . . . . . . . . . .
172 .9
403 .5
9 .7
(381 .7)
Balance at December 31, 2005 . . . . . . . . . . . . . . . . .
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cash dividends declared per share: $1 .63 . . . . . . .
Retirement of treasury shares . . . . . . . . . . . . . . . . .
Purchase for treasury . . . . . . . . . . . . . . . . . . . . . . . .
Issuance of stock under employee stock
plans—net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Stock-based compensation . . . . . . . . . . . . . . . . . . .
ESOP transactions . . . . . . . . . . . . . . . . . . . . . . . . . . .
Balance at December 31, 2006 . . . . . . . . . . . . . . . . .
Net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cash dividends declared per share: $1 .75 . . . . . . .
Retirement of treasury shares . . . . . . . . . . . . . . . . .
Issuance of stock under employee stock
plans—net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Stock-based compensation . . . . . . . . . . . . . . . . . . .
ESOP transactions . . . . . . . . . . . . . . . . . . . . . . . . . . .
FIN 48 implementation (Note 11) . . . . . . . . . . . . . . .
3,323 .8
(129 .1)
6 .2
359 .3
11 .7
3,571 .9
(3 .9)
(55 .2)
282 .0
10 .4
$ 9,724 .6
1,979 .6
(1,677 .0)
10,027 .2
2,662 .7
(1,763 .2)
10,926 .7
2,953 .0
(1,903 .9)
$(111 .9)
943
$ 103 .8
(6,874)
6,704
161
(386 .0)
377 .9
8 .4
5 .6
(106 .3)
934
104 .1
(2,297)
2,145
(130 .6)
122 .1
128
5 .8
5 .6
(100 .7)
910
101 .4
(76)
65
(3 .9)
3 .0
5 .5
(8 .6)
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Balance at December 31, 2007 . . . . . . . . . . . . . . . . . $3,805 .2
$11,967 .2
$ (95 .2)
899
$ 100 .5
As of December 31, 2007, we have purchased $2 .58 billion of our announced $3 .0 billion share repurchase
program . We acquired approximately 2 .1 million and 6 .7 million shares in 2006 and 2005, respectively, under this
program . No shares were repurchased in 2007 .
We have 5 million authorized shares of preferred stock . As of December 31, 2007 and 2006, no preferred stock
has been issued .
We have funded an employee benefit trust with 40 million shares of Lilly common stock to provide a source of
funds to assist us in meeting our obligations under various employee benefit plans . The funding had no net impact
on shareholders’ equity as we consolidate the employee benefit trust . The cost basis of the shares held in the
trust was $2 .64 billion and is shown as a reduction in shareholders’ equity, which offsets the resulting increases
of $2 .61 billion in additional paid-in capital and $25 million in common stock . Any dividend transactions between
us and the trust are eliminated . Stock held by the trust is not considered outstanding in the computation of earn-
ings per share . The assets of the trust were not used to fund any of our obligations under these employee benefit
plans in 2007, 2006, or 2005 .
We have an ESOP as a funding vehicle for the existing employee savings plan . The ESOP used the proceeds of a
loan from us to purchase shares of common stock from the treasury . The ESOP issued $200 million of third-party
debt, repayment of which was guaranteed by us (see Note 6) . The proceeds were used to purchase shares of our
common stock on the open market . Shares of common stock held by the ESOP will be allocated to participating
employees annually through 2017 as part of our savings plan contribution . The fair value of shares allocated each
period is recognized as compensation expense .
45
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Under a Shareholder Rights Plan adopted in 1998, all shareholders receive, along with each common share
owned, a preferred stock purchase right entitling them to purchase from the company one one-thousandth of
a share of Series B Junior Participating Preferred Stock (the Preferred Stock) at a price of $325. The rights are
exercisable only after the Distribution Date, which is generally the 10th business day after the date of a public
announcement that a person (the Acquiring Person) has acquired ownership of 15 percent or more of our com-
mon stock. We may redeem the rights for $.005 per right, up to and including the Distribution Date. The rights will
expire on July 28, 2008, unless we redeem them earlier.
The rights plan provides that, if an Acquiring Person acquires 15 percent or more of our outstanding common
stock and our redemption right has expired, generally each holder of a right (other than the Acquiring Person) will
have the right to purchase at the exercise price the number of shares of our common stock that have a value of two
times the exercise price.
Alternatively, if, in a transaction not approved by the board of directors, we are acquired in a business combi-
nation transaction or sell 50 percent or more of our assets or earning power after a Distribution Date, generally
each holder of a right (other than the Acquiring Person) will have the right to purchase at the exercise price the
number of shares of common stock of the acquiring company that have a value of two times the exercise price.
At any time after an Acquiring Person has acquired 15 percent or more but less than 50 percent of our out-
standing common stock, the board of directors may exchange the rights (other than those owned by the Acquiring
Person) for our common stock or Preferred Stock at an exchange ratio of one common share (or one one-thou-
sandth of a share of Preferred Stock) per right.
Note 10: Earnings Per Share
The following is a reconciliation of the denominators used in computing earnings per share before cumulative ef-
fect of a change in accounting principle:
Income before cumulative effect of a change in accounting
principle available to common shareholders . . . . . . . . . . . . . . . . .
$2,953.0
$2,662.7
$2,001.6
(Shares in thousands)
2007
2006
2005
Basic earnings per share
Weighted-average number of common shares outstanding,
including incremental shares . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1,090,430
1,086,239
1,088,754
Basic earnings per share before cumulative effect of a
change in accounting principle . . . . . . . . . . . . . . . . . . . . . . . . . . .
$2.71
$2.45
$1.84
Diluted earnings per share
Weighted-average number of common shares outstanding . . . . .
Stock options and other incremental shares. . . . . . . . . . . . . . . . . .
Weighted-average number of common shares outstanding—
1,088,929
1,821
1,085,337
2,153
1,088,115
4,035
diluted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1,090,750
1,087,490
1,092,150
Diluted earnings per share before cumulative effect of a
change in accounting principle . . . . . . . . . . . . . . . . . . . . . . . . . . .
$2.71
$2.45
$1.83
46
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Note 11: Income Taxes
Following is the composition of income taxes attributable to income before cumulative effect of a change in
accounting principle:
Current
Federal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Foreign . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
State . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Deferred
Federal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Foreign . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
State . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Unremitted earnings to be repatriated due to change in tax law . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Income taxes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2007
2006
2005
$489.5
412.1
27.7
929.3
53.0
(27.9)
(30.6)
—
(5.5)
$923.8
$197.7
390.6
(25.2)
563.1
78.3
113.5
0.4
—
192.2
$755.3
$ 517.4
649.8
11.6
1,178.8
89.4
(86.8)
(0.5)
(465.0)
(462.9)
$ 715.9
Signifi cant components of our deferred tax assets and liabilities as of December 31 are as follows:
Deferred tax assets
Tax loss carryforwards and carrybacks . . . . . . . . . . . . . . . . . . . . .
Compensation and benefi ts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Inventory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Tax credit carryforwards and carrybacks . . . . . . . . . . . . . . . . . . . .
Asset purchases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Financial instruments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Sale of intangibles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Asset disposals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Valuation allowances . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2007
2006
$ 804.3
654.8
546.2
361.5
95.4
83.6
69.1
62.9
318.4
2,996.2
(511.2)
$ 293.2
713.4
504.4
286.9
98.0
83.2
161.3
94.6
276.2
2,511.2
(493.7)
Total deferred tax assets. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2,485.0
2,017.5
Deferred tax liabilities
Prepaid employee benefi ts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Property and equipment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Intangibles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total deferred tax liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
(675.9)
(662.2)
(532.5)
(285.1)
(2,155.7)
(485.8)
(701.2)
—
(237.0)
(1,424.0)
Deferred tax assets—net . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$ 329.3
$ 593.5
At December 31, 2007, we had net operating losses and other carryforwards for international and U.S. income
tax purposes of $1.15 billion: $27.0 million will expire within 10 years; $1.09 billion will expire between 10 and 20
years; and $36.9 million of the carryforwards will never expire. The primary components of the remaining portion
of the deferred tax asset for tax loss carryforwards and carrybacks are related to net operating losses for state in-
come tax purposes that are fully reserved and a capital loss of $433.6 million, which we expect to be carried back.
We also have tax credit carryforwards and carrybacks of $361.5 million available to reduce future income taxes;
$80.7 million will be carried back; $34.1 million of the tax credit carryforwards will expire after 5 years; and
$13.3 million of the tax credit carryforwards will never expire. The remaining portion of the tax credit carryfor-
wards is related to state tax credits that are fully reserved. The increase in both the deferred tax asset for tax loss
carryforwards and carrybacks and the deferred tax liability for intangibles resulted primarily from the acquisition
47
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of ICOS. See Note 3 for further discussion.
Domestic and Puerto Rican companies contributed approximately 7 percent, 18 percent, and 43 percent in
2007, 2006, and 2005, respectively, to consolidated income before income taxes and cumulative effect of a change
in accounting principle. We have a subsidiary operating in Puerto Rico under a tax incentive grant. The current tax
incentive grant will not expire prior to 2017.
The American Jobs Creation Act of 2004 (AJCA) created a temporary incentive for U.S. corporations to repa-
triate undistributed income earned abroad by providing an 85 percent dividends received deduction for certain
dividends from controlled foreign corporations in 2005. We recorded a related tax liability of $465.0 million as of
December 31, 2004, and subsequently repatriated $8.00 billion in incentive dividends, as defi ned in the AJCA, dur-
ing 2005. At December 31, 2007, we had an aggregate of $8.79 billion of unremitted earnings of foreign subsidiaries
that have been or are intended to be permanently reinvested for continued use in foreign operations and that, if
distributed, would result in taxes at approximately the U.S. statutory rate.
Cash payments of income taxes totaled $1.01 billion, $864.0 million, and $1.78 billion in 2007, 2006, and 2005,
respectively. The higher cash payments of income taxes in 2005 are primarily attributable to the tax liability asso-
ciated with the implementation of the AJCA and the resolution of an IRS examination for the years 1998 to 2000.
Following is a reconciliation of the effective income tax rate applicable to income before income taxes and
cumulative effect of a change in accounting principle:
United States federal statutory tax rate . . . . . . . . . . . . . . . . . . . . . . . .
Add (deduct)
2007
35.0%
2006
35.0%
2005
35.0%
International operations, including Puerto Rico . . . . . . . . . . . . . . .
(11.6)
(6.7)
(4.8)
Non-deductible acquired in-process research and
development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
General business credits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Sundry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Effective income tax rate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
5.4
(1.6)
(3.4)
23.8%
—
(1.4)
(4.8)
22.1%
—
(1.5)
(2.4)
26.3%
We adopted FIN 48 on January 1, 2007. FIN 48 prescribes a recognition threshold and measurement attribute
for the fi nancial statement recognition and measurement of a tax position taken or expected to be taken in a tax
return. As a result of the implementation of FIN 48, we reclassifi ed $921.4 million of income taxes payable from
current to non-current liabilities. We also recognized an increase of $8.6 million in the liability for unrecognized
tax benefi ts, and an offsetting reduction to the January 1, 2007 balance of retained earnings. A reconciliation of the
beginning and ending amount of gross unrecognized tax benefi ts is as follows:
Beginning balance at January 1, 2007 . . . . . . . . . . . . . . . . . . . . . . . . . .
Additions based on tax positions related to the current year . . . . . . .
Additions for tax positions of prior years . . . . . . . . . . . . . . . . . . . . . . .
Reductions for tax positions of prior years . . . . . . . . . . . . . . . . . . . . . .
Settlements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Balance at December 31, 2007 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
$1,340.7
206.4
35.6
(15.1)
(2.3)
$1,565.3
The total amount of unrecognized tax benefi ts that, if recognized, would affect our effective tax rate was
$1.46 billion at December 31, 2007.
We fi le income tax returns in the U.S. federal jurisdiction and various state, local, and non-U.S. jurisdictions.
We are no longer subject to U.S. federal, state and local, or non-U.S. income tax examinations in major taxing
jurisdictions for years before 2001. We are currently under audit by the Internal Revenue Service (IRS) for tax
years 2001-2004, and management believes it is reasonably possible that a substantial portion of this audit will
conclude within the next 12 months; however, the ultimate resolution of all issues in the audit period is dependent
upon a number of factors, including the potential for formal administrative and legal proceedings. Resolution of a
substantial portion of the audit would bring certainty to specifi c tax positions addressed in the audit, allowing for a
reduction in gross unrecognized tax benefi ts. If such resolution is reached within the next 12 months, we estimate
a reduction in gross unrecognized tax benefi ts in the range of $600 million to $700 million. As a result, our consoli-
dated results of operations could benefi t up to $190 million through a reduction in income tax expense. The majori-
ty of this reduction in unrecognized tax benefi ts relates to intercompany pricing positions that were agreed with the
IRS in a prior audit cycle for which a prepayment of tax was made in 2005. We anticipate that any tax due upon such
48
resolution has been prepaid or tax carryovers will be utilized, which will result in no additional cash payments.
We recognize both accrued interest and penalties related to unrecognized tax benefi ts in income tax expense.
During the years ended December 31, 2007, 2006, and 2005, we recognized $66.6 million, $51.2 million, and
$44.2 million in interest and penalties, respectively. At December 31, 2007 and 2006, our accruals for the payment
of interest and penalties totaled $238.4 million and $171.8 million, respectively. Substantially all of the expense
and accruals relate to interest.
Note 12: Retirement Benefi ts
In September 2006, the FASB issued SFAS No. 158, Employers’ Accounting for Defi ned Benefi t Pension and Other
Postretirement Plans—an amendment of FASB Statements No. 87, 88, 106, and 132(R). SFAS 158 required the recog-
nition of the overfunded or underfunded status of a defi ned benefi t postretirement plan as an asset or liability in its
statement of fi nancial position, the measurement of a plan’s assets and its obligations that determine its funded sta-
tus as of the end of the employer’s fi scal year, and the recognition of changes in that funded status through compre-
hensive income in the year in which the changes occur. We adopted the provisions of SFAS 158 on December 31, 2006.
We use a measurement date of December 31 to develop the change in benefi t obligation, change in plan assets,
funded status, and amounts recognized in the consolidated balance sheets at December 31 for our defi ned benefi t
pension and retiree health benefi t plans, which were as follows:
Defi ned Benefi t Pension Plans
2007
2006
Retiree Health Benefi t Plans
2006
2007
Change in benefi t obligation
Benefi t obligation at beginning of year . . . . . . . . . . . . . . . . $6,480.3
287.1
Service cost . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
362.4
Interest cost . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
(373.1)
Actuarial (gain) loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
(311.0)
Benefi ts paid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Plan amendments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
32.7
Foreign currency exchange rate changes and other
$5,628.4
280.0
343.5
64.9
(291.2)
—
$1,740.7
70.4
101.4
16.4
(81.6)
(227.7)
$1,673.6
72.2
97.9
(25.0)
(82.5)
—
adjustments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Benefi t obligation at end of year . . . . . . . . . . . . . . . . . . . . .
82.6
6,561.0
454.7
6,480.3
3.2
1,622.8
4.5
1,740.7
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Change in plan assets
Fair value of plan assets at beginning of year . . . . . . . . . .
Actual return on plan assets . . . . . . . . . . . . . . . . . . . . . . .
Employer contribution . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Benefi ts paid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Foreign currency exchange rate changes and other
6,519.0
833.8
202.9
(301.4)
5,482.4
913.1
221.3
(287.9)
1,157.3
147.4
125.4
(81.6)
adjustments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Fair value of plan assets at end of year . . . . . . . . . . . . . . .
49.9
7,304.2
190.1
6,519.0
—
1,348.5
743.2
Funded status . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1,143.3
Unrecognized net actuarial loss . . . . . . . . . . . . . . . . . . . . .
Unrecognized prior service cost (benefi t) . . . . . . . . . . . . .
88.4
Net amount recognized . . . . . . . . . . . . . . . . . . . . . . . . . . . . $1,974.9
38.7
1,788.6
63.4
$1,890.7
(274.3)
820.3
(297.7)
$ 248.3
Amounts recognized in the consolidated balance sheet
consisted of
Prepaid pension . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $1,670.5
(47.9)
Other current liabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Accrued retirement benefi t . . . . . . . . . . . . . . . . . . . . . . . . .
(879.4)
Accumulated other comprehensive loss before
$1,091.5
(43.4)
(1,009.4)
$ —
(8.6)
(265.7)
income taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1,231.7
Net amount recognized . . . . . . . . . . . . . . . . . . . . . . . . . . . . $1,974.9
1,852.0
$1,890.7
522.6
$ 248.3
965.7
103.0
171.1
(82.5)
—
1,157.3
(583.4)
931.8
(85.7)
$ 262.7
$ —
(5.9)
(577.5)
846.1
$ 262.7
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The unrecognized net actuarial loss and unrecognized prior service cost (benefi t) have not yet been recognized
in net periodic pension costs and are included in accumulated other comprehensive loss at December 31, 2007.
In 2008, we expect to recognize from accumulated other comprehensive loss as components of net periodic
benefi t cost $71.5 million of unrecognized net actuarial loss and $9.5 million of unrecognized prior service cost
related to our defi ned benefi t pension plans and $65.2 million of unrecognized net actuarial loss and $36.0 million
of unrecognized prior service benefi t related to our retiree health benefi t plans. We do not expect any plan assets
to be returned to us in 2008.
The following represents our weighted-average assumptions as of December 31:
(Percents)
Defi ned Benefi t Pension Plans
2007
2006
Retiree Health Benefi t Plans
2006
2007
Weighted-average assumptions as of December 31
Discount rate for benefi t obligation . . . . . . . . . . . . . . . . . .
Discount rate for net benefi t costs . . . . . . . . . . . . . . . . . . .
Rate of compensation increase for benefi t obligation . . .
Rate of compensation increase for net benefi t costs . . . .
Expected return on plan assets for net benefi t costs . . .
6.4
5.7
4.6
4.6
9.0
5.7
5.8
4.6
4.7
9.0
6.7
6.0
—
—
9.0
6.0
6.0
—
—
9.0
In evaluating the expected return on plan assets, we have considered our historical assumptions compared
with actual results, an analysis of current market conditions, asset allocations, and the views of leading fi nancial
advisers and economists. Our plan assets in our U.S. defi ned benefi t pension and retiree health plans comprise
approximately 83 percent of our worldwide benefi t plan assets. Including the investment losses due to overall mar-
ket conditions in 2001 and 2002, our 10- and 20-year annualized rates of return on our U.S. defi ned benefi t pension
plans and retiree health benefi t plan were approximately 8.9 percent and 11.3 percent, respectively, as of Decem-
ber 31, 2007. Health-care-cost trend rates were assumed to increase at an annual rate of 9.3 percent in 2008,
decreasing by approximately 0.6 percent per year to an ultimate rate of 5.5 percent by 2014.
The following benefi t payments, which refl ect expected future service, as appropriate, are expected to be paid
as follows:
Defi ned benefi t pension plans . . . . . . . . . . .
$324.2
$347.5
$362.5
$367.8
$374.1 $2,012.1
2008
2009
2010
2011
2012
2013-2017
Retiree health benefi t plans—gross . . . . . .
Medicare rebates . . . . . . . . . . . . . . . . . . . . .
Retiree health benefi t plans—net . . . . . . . .
$ 86.0
(5.8)
$ 80.2
$ 95.9
(7.9)
$ 88.0
$ 99.1
(8.5)
$ 90.6
$101.7
(8.9)
$ 92.8
$102.4
(9.8)
$ 92.6
$ 527.9
(56.2)
$ 471.7
The total accumulated benefi t obligation for our defi ned benefi t pension plans was $5.69 billion and $5.65 billion
at December 31, 2007 and 2006, respectively. The projected benefi t obligation and fair value of the plan assets for
the defi ned benefi t pension plans with projected benefi t obligations in excess of plan assets were $1.04 billion and
$160.9 million, respectively, as of December 31, 2007, and $2.23 billion and $1.22 billion, respectively, as of Decem-
ber 31, 2006. The accumulated benefi t obligation and fair value of the plan assets for the defi ned benefi t pension
plans with accumulated benefi t obligations in excess of plan assets were $825.8 million and $46.9 million, respec-
tively, as of December 31, 2007, and $805.0 million and $37.7 million, respectively, as of December 31, 2006.
Net pension and retiree health benefi t expense included the following components:
Defi ned Benefi t
Pension Plans
2006
2007
2005
2007
Retiree Health
Benefi t Plans
2006
Components of net periodic benefi t cost
Service cost . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Interest cost . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Expected return on plan assets . . . . . . . . . . . . .
Amortization of prior service cost (benefi t) . . . .
Recognized actuarial loss . . . . . . . . . . . . . . . . . .
Net periodic benefi t cost . . . . . . . . . . . . . . . . . . .
$287.1
362.4
(548.2)
7.7
130.0
$239.0
$280.0 $297.4
296.2
(445.9)
7.6
106.7
$286.6 $262.0
343.5
(494.8)
8.3
149.6
$ 70.4
101.4
(102.1)
(15.7)
95.0
$149.0
$ 72.2
97.9
(89.9)
(15.6)
107.9
$172.5
2005
$ 61.5
80.7
(75.6)
(15.6)
86.6
$137.6
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If the health-care-cost trend rates were to be increased by one percentage point each future year, the December
31, 2007, accumulated postretirement benefi t obligation would increase by $226.6 million (14.0 percent) and the ag-
gregate of the service cost and interest cost components of the 2007 annual expense would increase by $27.8 million
(16.2 percent). A one-percentage-point decrease in these rates would decrease the December 31, 2007, accumulated
postretirement benefi t obligation by $187.9 million (11.6 percent) and the aggregate of the 2007 service cost and inter-
est cost by $22.7 million (13.2 percent).
The following represents the amounts recognized in other comprehensive income in 2007:
Plan amendments during period . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Amortization of prior service cost (benefi t) included in
net income . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Net change in unrecognized prior service cost (benefi t)
Defi ned Benefi t
Pension Plans
Retiree Health
Benefi t Plans
Total
$ 32.7
$(227.7)
$(195.0)
(7.7)
15.7
8.0
not recognized in net income during period . . . . . . . . . . . . . . . .
25.0
(212.0)
(187.0)
Actuarial gain arising during period . . . . . . . . . . . . . . . . . . . . . . . . . . .
Amortization of net actuarial loss included in net income . . . . . . . . .
Net change in unrecognized net actuarial loss not included
(515.3)
(130.0)
(16.5)
(95.0)
in net income during period . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total other comprehensive income during period . . . . . . . . . . . . .
(645.3)
$(620.3)
(111.5)
$(323.5)
(531.8)
(225.0)
(756.8)
$(943.8)
We have defi ned contribution savings plans that cover our eligible employees worldwide. The purpose of these
defi ned contribution plans is generally to provide additional fi nancial security during retirement by providing em-
ployees with an incentive to save. Our contributions to the plan are based on employee contributions and the level
of our match. Expenses under the plans totaled $112.3 million, $106.5 million, and $96.1 million for the years 2007,
2006, and 2005, respectively.
We provide certain other postemployment benefi ts primarily related to disability benefi ts and accrue for the
related cost over the service lives of employees. Expenses associated with these benefi t plans in 2007, 2006, and
2005 were not signifi cant.
Our U.S. defi ned benefi t pension and retiree health benefi t plan investment allocation strategy currently
comprises approximately 85 percent to 95 percent growth investments and 5 percent to 15 percent fi xed-income
investments. Within the growth investment classifi cation, the plan asset strategy encompasses equity and equity-
like instruments that are expected to represent approximately 75 percent of our plan asset portfolio of both public
and private market investments. The largest component of these equity and equity-like instruments is public equity
securities that are well diversifi ed and invested in U.S. and international small-to-large companies. The remaining
portion of the growth investment classifi cation is represented by other alternative growth investments.
Our defi ned benefi t pension plan and retiree health plan asset allocations as of December 31 are as follows:
(Percents)
Percentage of
Pension Plan Assets
2007
2006
Percentage of
Retiree Health Plan Assets
2007
2006
Asset Category
Equity securities and equity-like instruments . . . . . . . . .
Debt securities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Real estate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Total . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
75
10
1
14
100
78
9
1
12
100
78
11
—
11
100
80
10
—
10
100
In 2008, we expect to contribute approximately $70 million to our defi ned benefi t pension plans to satisfy mini-
mum funding requirements for the year. In addition, we expect to contribute approximately $110 million of additional
discretionary funding in 2008 to our defi ned benefi t plans. We do not expect to make any contributions to our post-
retirement health benefi t plans during 2008.
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Note 13: Contingencies
We are a party to various legal actions, government investigations, and environmental proceedings. The most
signifi cant of these are described below. While it is not possible to determine the outcome of these matters, we
believe that, except as specifi cally noted below, the resolution of all such matters will not have a material adverse
effect on our consolidated fi nancial position or liquidity, but could possibly be material to our consolidated results
of operations in any one accounting period.
Patent Litigation
We are engaged in the following patent litigation matters brought pursuant to procedures set out in the Hatch-
Waxman Act (the Drug Price Competition and Patent Term Restoration Act of 1984):
• Barr Laboratories, Inc. (Barr), submitted an Abbreviated New Drug Application (ANDA) in 2002 seeking permission
to market a generic version of Evista prior to the expiration of our relevant U.S. patents (expiring in 2012-2017)
and alleging that these patents are invalid, not enforceable, or not infringed. In November 2002, we fi led a lawsuit
against Barr in the U.S. District Court for the Southern District of Indiana, seeking a ruling that these patents are
valid, enforceable, and being infringed by Barr. Teva has also submitted an ANDA seeking permission to market
a generic version of Evista. In June 2006, we fi led a similar lawsuit against Teva in the U.S. District Court for the
Southern District of Indiana. The lawsuit against Teva is currently scheduled for trial beginning March 9, 2009, while
no trial date has been set in the lawsuit against Barr. We believe that Barr’s and Teva’s claims are without merit
and we expect to prevail. However, it is not possible to determine the outcome of this litigation, and accordingly, we
can provide no assurance that we will prevail. An unfavorable outcome could have a material adverse impact on our
consolidated results of operations, liquidity, and fi nancial position.
• Sicor Pharmaceuticals, Inc. (Sicor), Mayne Pharma (USA) Inc. (Mayne), and Sun Pharmaceutical Industries Inc.
(Sun) each submitted ANDAs seeking permission to market generic versions of Gemzar prior to the expiration
of our relevant U.S. patents (compound patent expiring in 2010 and method-of-use patent expiring in 2013), and
alleging that these patents are invalid. We fi led lawsuits in the U.S. District Court for the Southern District of
Indiana against Sicor (February 2006) and Mayne (October 2006), seeking rulings that these patents are valid and
are being infringed. In November 2007, the lawsuit against Mayne was stayed and administratively closed by the
court. Also in November 2007, Sun fi led a declaratory judgment action in the United States District Court for the
Eastern District of Michigan, seeking a ruling that our method-of-use patent is invalid or unenforceable, or would
not be infringed by the sale of Sun’s generic product. Sun informed us in December 2007 that it is also challenging
our compound patent, and that patent has now been added to the declaratory judgment action. In January 2008,
we fi led a second lawsuit against Mayne in response to a second ANDA fi led by Mayne for a new dosage strength.
We expect to prevail in this litigation and believe that these claims are without merit. However, it is not possible
to determine the outcome of this litigation, and accordingly, we can provide no assurance that we will prevail. An
unfavorable outcome could have a material adverse impact on our consolidated results of operations, liquidity, and
fi nancial position.
• Actavis Elizabeth LLC (Actavis), Glenmark Pharmaceuticals Inc., USA (Glenmark), Sun Pharmaceutical Industries
Limited (Sun), Sandoz Inc. (Sandoz), Mylan Pharmaceuticals Inc. (Mylan), Teva Pharmaceuticals USA, Inc. (Teva),
Apotex Inc. (Apotex), Aurobindo Pharma Ltd. (Aurobindo), Synthon Laboratories, Inc. (Synthon), and Zydus
Pharmaceuticals, USA, Inc. (Zydus) each submitted an ANDA seeking permission to market generic versions
of Strattera prior to the expiration of our relevant U.S. patent (expiring in 2017), and alleging that this patent
is invalid. We fi led a lawsuit against Actavis in the United States District Court for the District of New Jersey in
August 2007. Sandoz fi led a declaratory judgment action in the same court, but its case has been dismissed. In
September 2007, we amended the complaint in the New Jersey lawsuit to add Glenmark, Sun, Sandoz, Mylan,
Teva, Apotex, Aurobindo, Synthon, and Zydus as defendants. We fi led a second action against Synthon in the United
States District Court for the Eastern District of Virginia. Synthon has fi led a motion to dismiss our lawsuit in New
Jersey. In December 2007, Zydus agreed to entry of a consent judgment in which Zydus conceded the validity
and enforceability of the patent and agreed to a permanent injunction. We expect to prevail in this litigation and
believe that these claims are without merit. However, it is not possible to determine the outcome of this litigation,
and accordingly, we can provide no assurance that we will prevail. An unfavorable outcome could have a material
adverse impact on our consolidated results of operations, liquidity, and fi nancial position.
We have received challenges to Zyprexa patents in a number of countries outside the U.S.:
• In Canada, several generic pharmaceutical manufacturers have challenged the validity of our Zyprexa compound
and method-of-use patent (expiring in 2011). In April 2007, the Canadian Federal Court ruled against the fi rst
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challenger, Apotex Inc. (Apotex), and Apotex has appealed that ruling. In June 2007, the Canadian Federal Court
held that the invalidity allegations of a second challenger, Novopharm Ltd. (Novopharm), were justifi ed and denied
our request that Novopharm be prohibited from receiving marketing approval for generic olanzapine in Canada.
Novopharm began selling generic olanzapine in Canada in the third quarter of 2007. We have appealed that
decision and sued Novopharm for patent infringement. The appeal was dismissed. In November 2007, Apotex fi led
an action seeking a declaration of the invalidity of our Zyprexa compound and method-of-use patents (expiring in
2011). The trial court ruled in our favor in February 2007. Apotex will likely appeal.
• In Germany, generic pharmaceutical manufacturers Egis-Gyogyszergyar and Neolabs Ltd. challenged the validity
of our Zyprexa compound and method-of-use patents (expiring in 2011). In June 2007, the German Federal
Patent Court held that our patent is invalid. We are appealing the decision. Generic olanzapine was launched by
competitors in Germany in the fourth quarter of 2007.
• We have received challenges in a number of other countries, including Spain, the United Kingdom (U.K.), and
several smaller European countries. In Spain, we have been successful at both the trial and appellate court
levels in defeating the generic manufacturers’ challenge, but we anticipate further legal challenges from generic
manufacturers. In the U.K., a trial date has tentatively been set for July 2008.
We are vigorously contesting the various legal challenges to our Zyprexa patents on a country-by-country
basis. We cannot determine the outcome of this litigation. The availability of generic olanzapine in Canada and
Germany will have a material adverse impact on our consolidated results of operations. The availability of generic
olanzapine in additional markets could have a material adverse impact on our consolidated results of operations.
In June 2002, Ariad Pharmaceuticals, Inc., the Massachusetts Institute of Technology, the Whitehead Insti-
tute for Biomedical Research, and the President and Fellows of Harvard College in the U.S. District Court for the
District of Massachusetts sued us, alleging that sales of two of our products, Xigris and Evista, were inducing the
infringement of a patent related to the discovery of a natural cell signaling phenomenon in the human body, and
seeking royalties on past and future sales of these products. On May 4, 2006, a jury in Boston issued an initial deci-
sion in the case that Xigris and Evista sales infringe the patent. The jury awarded the plaintiffs approximately
$65 million in damages, calculated by applying a 2.3 percent royalty to all U.S. sales of Xigris and Evista from the
date of issuance of the patent through the date of trial. In addition, a separate bench trial with the U.S. District
Court of Massachusetts was held in August 2006, on our contention that the patent is unenforceable and impermis-
sibly covers natural processes. In June 2005, the United States Patent and Trademark Offi ce (USPTO) commenced
a reexamination of the patent, and in August 2007 took the position that the Ariad claims at issue are unpatent-
able, a position that Ariad continues to contest. In September 2007, the Court entered a fi nal judgment indicating
that Ariad’s claims are patentable, valid, and enforceable, and fi nding damages in the amount of $65 million plus
a 2.3 percent royalty on net U.S. sales of Xigris and Evista since the time of the jury decision. However, the Court
deferred the requirement to pay any damages until after all rights to appeal have been exhausted. We plan to ap-
peal this judment. We believe that these allegations are without legal merit, that we will ultimately prevail on these
issues, and therefore that the likelihood of any monetary damages is remote.
Government Investigations and Related Litigation
In March 2004, the Offi ce of the U.S. Attorney for the Eastern District of Pennsylvania (EDPA) advised us that it had
commenced an investigation related to our U.S. marketing and promotional practices, including our communica-
tions with physicians and remuneration of physician consultants and advisors, with respect to Zyprexa, Prozac, and
Prozac Weekly. In November 2007, we received a grand jury subpoena from the EDPA for a broad range of docu-
ments related to Zyprexa. A number of State Medicaid Fraud Control Units are coordinating with the EDPA in its
investigation of any Medicaid-related claims relating to our marketing and promotion of Zyprexa. In October 2005,
the EDPA advised that it is also conducting an inquiry regarding certain rebate agreements we entered into with a
pharmacy benefi t manager covering Axid, Evista, Humalog, Humulin, Prozac, and Zyprexa. The inquiry includes a
review of our Medicaid best price reporting related to the product sales covered by the rebate agreements.
In June 2005, we received a subpoena from the Offi ce of the Attorney General, Medicaid Fraud Control Unit, of
the State of Florida, seeking production of documents relating to sales of Zyprexa and our marketing and promo-
tional practices with respect to Zyprexa.
In September 2006, we received a subpoena from the California Attorney General’s Offi ce seeking production
of documents related to our efforts to obtain and maintain Zyprexa’s status on California’s formulary, marketing
and promotional practices with respect to Zyprexa, and remuneration of health care providers.
In February 2007, we received a subpoena from the Offi ce of the Attorney General of the State of Illinois,
seeking production of documents and information relating to sales of Zyprexa and our marketing and promotional
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practices, including our communications with physicians and remuneration of physician consultants and advisors,
with respect to Zyprexa.
Beginning in August 2006, we have received civil investigative demands or subpoenas from the attorneys
general of a number of states under various state consumer protection laws. Most of these requests are now part
of a multistate investigative effort being coordinated by an executive committee of attorneys general. We are aware
that approximately 30 states are participating in this joint effort, and it is possible that additional states will join
the investigation. These attorneys general are seeking a broad range of Zyprexa documents, including documents
relating to sales, marketing and promotional practices, and remuneration of health care providers. In addition, we
have been named as a defendant in a private suit in California State Court, which was removed to federal court,
alleging violations of the California False Claims Act with respect to certain Zyprexa marketing and promotional
practices. This suit was brought by an individual on behalf of the government, under the qui tam provision of the
California False Claims Act.
We are cooperating in each of these investigations, including providing a broad range of documents and infor-
mation relating to the investigations. It is possible that other Lilly products could become subject to investigation
and that the outcome of these matters could include criminal charges and fi nes, penalties, or other monetary or
nonmonetary remedies. We cannot determine the outcome of these matters or reasonably estimate the amount or
range of amounts of any fi nes or penalties that might result from an adverse outcome. It is possible, however, that
an adverse outcome could have a material adverse impact on our consolidated results of operations, liquidity, and
fi nancial position. We have implemented and continue to review and enhance a broadly based compliance program
that includes comprehensive compliance-related activities designed to ensure that our marketing and promotional
practices, physician communications, remuneration of health care professionals, managed care arrangements,
and Medicaid best price reporting comply with applicable laws and regulations.
Product Liability and Related Litigation
We have been named as a defendant in a large number of Zyprexa product liability lawsuits in the United States
and have been notifi ed of many other claims of individuals who have not fi led suit. The lawsuits and unfi led claims
(together the “claims”) allege a variety of injuries from the use of Zyprexa, with the majority alleging that the
product caused or contributed to diabetes or high blood-glucose levels. The claims seek substantial compensatory
and punitive damages and typically accuse us of inadequately testing for and warning about side effects of Zyprexa.
Many of the claims also allege that we improperly promoted the drug. Almost all of the federal lawsuits are part of
a Multi-District Litigation (MDL) proceeding before The Honorable Jack Weinstein in the Federal District Court for
the Eastern District of New York (MDL No. 1596).
Since June 2005, we have entered into agreements with various claimants’ attorneys involved in U.S. Zyprexa
product liability litigation to settle a substantial majority of the claims. The agreements cover a total of approxi-
mately 31,200 claimants, including a large number of previously fi led lawsuits and other asserted claims. The two
primary settlements were as follows:
• In June 2005, we reached an agreement in principle (and in September 2005 a fi nal agreement) to settle more
than 8,000 claims for $690.0 million plus $10.0 million to cover administration of the settlement.
• In January 2007, we reached agreements with a number of plaintiffs’ attorneys to settle more than 18,000 claims
for approximately $500 million.
The 2005 settlement totaling $700.0 million was paid during 2005. The January 2007 settlements were paid
during 2007.
We are prepared to continue our vigorous defense of Zyprexa in all remaining claims. The U.S. Zyprexa product
liability claims not subject to these agreements include approximately 325 lawsuits in the U.S. covering approxi-
mately 1,235 plaintiffs. Trial dates have been set for June 23, 2008, in the Eastern District of New York, for several
of the U.S. plaintiffs.
In early 2005, we were served with four lawsuits seeking class action status in Canada on behalf of patients
who took Zyprexa. One of these four lawsuits has been certifi ed for residents of Quebec, and a second has been
certifi ed in Ontario and includes all Canadian residents, except for residents of Quebec and British Columbia. The
allegations in the Canadian actions are similar to those in the litigation pending in the U.S.
We have insurance coverage for a portion of our Zyprexa product liability claims exposure. The third-party insur-
ance carriers have raised defenses to their liability under the policies and are seeking to rescind the policies. The
dispute was the subject of litigation in the federal court in Indianapolis against certain of the carriers and in arbitra-
tion in Bermuda against other carriers. In the second half of 2007, we reached settlements resolving the vast major-
ity of the disputed insurance claims, and a portion of the insurance proceeds were paid to us prior to the end of 2007.
54
Since the beginning of 2005, we have recorded aggregate net pretax charges of $1.61 billion for Zyprexa
product liability matters. The net charges, which take into account our actual and expected insurance recoveries,
covered the following:
• The cost of the Zyprexa product liability settlements to date; and
• Reserves for product liability exposures and defense costs regarding the known Zyprexa product liability claims
and expected future claims to the extent we could formulate a reasonable estimate of the probable number and
cost of the claims.
In December 2004, we were served with two lawsuits brought in state court in Louisiana on behalf of the
Louisiana Department of Health and Hospitals, alleging that Zyprexa caused or contributed to diabetes or high
blood-glucose levels, and that we improperly promoted the drug. These cases have been removed to federal court
and are now part of the MDL proceedings in the Eastern District of New York. In these actions, the Department
of Health and Hospitals seeks to recover the costs it paid for Zyprexa through Medicaid and other drug-benefi t
programs, as well as the costs the department alleges it has incurred and will incur to treat Zyprexa-related ill-
nesses. We have been served with similar lawsuits fi led by the states of Alaska, Mississippi, Montana, New Mexico,
Pennsylvania, South Carolina, Utah, and West Virginia in the courts of the respective states. The Mississippi,
Montana, New Mexico, and West Virginia cases have been removed to federal court and are now part of the MDL
proceedings in the Eastern District of New York. The Alaska case is scheduled for trial beginning March 3, 2008.
In 2005, two lawsuits were fi led in the Eastern District of New York purporting to be nationwide class actions
on behalf of all consumers and third-party payors, excluding governmental entities, which have made or will make
payments for their members or insured patients being prescribed Zyprexa. These actions have now been consoli-
dated into a single lawsuit, which is brought under certain state consumer protection statutes, the federal civil
RICO statute, and common law theories, seeking a refund of the cost of Zyprexa, treble damages, punitive dam-
ages, and attorneys’ fees. Two additional lawsuits were fi led in the Eastern District of New York in 2006 on similar
grounds. In 2007, The Pennsylvania Employees Trust Fund brought claims in state court in Pennsylvania as insurer
of Pennsylvania state employees, who were prescribed Zyprexa on similar grounds as described in the New York
cases. As with the product liability suits, these lawsuits allege that we inadequately tested for and warned about
side effects of Zyprexa and improperly promoted the drug.
We cannot determine with certainty the additional number of lawsuits and claims that may be asserted. The
ultimate resolution of Zyprexa product liability and related litigation could have a material adverse impact on our
consolidated results of operations, liquidity, and fi nancial position.
In addition, we have been named as a defendant in numerous other product liability lawsuits involving pri-
marily diethylstilbestrol (DES) and thimerosal. The majority of these claims are covered by insurance, subject to
deductibles and coverage limits.
Because of the nature of pharmaceutical products, it is possible that we could become subject to large num-
bers of product liability and related claims for other products in the future. In the past few years, we have experi-
enced diffi culties in obtaining product liability insurance due to a very restrictive insurance market. Therefore, for
substantially all of our currently marketed products, we have been and expect that we will continue to be largely
self-insured for future product liability losses. In addition, as noted above, there is no assurance that we will be
able to fully collect from our insurance carriers on past claims.
Environmental Matters
Under the Comprehensive Environmental Response, Compensation, and Liability Act, commonly known as Super-
fund, we have been designated as one of several potentially responsible parties with respect to fewer than 10 sites.
Under Superfund, each responsible party may be jointly and severally liable for the entire amount of the cleanup.
We also continue remediation of certain of our own sites. We have accrued for estimated Superfund cleanup costs,
remediation, and certain other environmental matters. This takes into account, as applicable, available information
regarding site conditions, potential cleanup methods, estimated costs, and the extent to which other parties can be
expected to contribute to payment of those costs. We have limited liability insurance coverage for certain environ-
mental liabilities.
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Note 14: Other Comprehensive Income (Loss)
The accumulated balances related to each component of other comprehensive income (loss) were as follows:
Beginning balance at January 1, 2007 . . . . . . . . . . .
Other comprehensive income (loss) . . . . . . . . . . . .
Balance at December 31, 2007 . . . . . . . . . . . . . . . . .
Foreign Currency
Translation
Gains
$ 560.4
756.6
$1,317.0
Unrealized
Gains on
Securities
$20.0
(5.4)
$14.6
Defi ned Benefi t
Pension and
Retiree Health
Benefi t Plans
$(1,803.3)
651.7
$ (1,151.6)
Effective
Portion of
Cash Flow
Hedges
Accumulated
Other
Comprehensive
Income (Loss)
$(165.8) $(1,388.7)
1,401.9
$(166.8) $ 13.2
(1.0)
The amounts above are net of income taxes. The income taxes associated with the unrecognized losses and prior
service costs (Note 12) were an expense of $292.1 million for 2007. The income taxes related to the other com-
ponents of comprehensive income were not signifi cant, as income taxes were not provided for foreign currency
translation.
The unrealized gains (losses) on securities is net of reclassifi cation adjustments of $5.8 million, $16.9 mil-
lion, and $9.1 million, net of tax, in 2007, 2006, and 2005, respectively, for net realized gains on sales of securities
included in net income. The effective portion of cash fl ow hedges is net of reclassifi cation adjustments of $8.8 mil-
lion, $2.3 million, and $3.8 million, net of tax, in 2007, 2006, and 2005, respectively, for realized losses on foreign
currency options and $11.6 million, $17.1 million, and $21.4 million, net of tax, in 2007, 2006, and 2005, respectively,
for interest expense on interest rate swaps designated as cash fl ow hedges.
Generally, the assets and liabilities of foreign operations are translated into U.S. dollars using the current
exchange rate. For those operations, changes in exchange rates generally do not affect cash fl ows; therefore,
resulting translation adjustments are made in shareholders’ equity rather than in income.
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Management’s Reports
Management’s Report for Financial Statements—Eli Lilly and Company and Subsidiaries
Management of Eli Lilly and Company and subsidiaries is responsible for the accuracy, integrity, and fair presen-
tation of the fi nancial statements. The statements have been prepared in accordance with generally accepted ac-
counting principles in the United States and include amounts based on judgments and estimates by management.
In management’s opinion, the consolidated fi nancial statements present fairly our fi nancial position, results of
operations, and cash fl ows.
In addition to the system of internal accounting controls, we maintain a code of conduct (known as The Red
Book) that applies to all employees worldwide, requiring proper overall business conduct, avoidance of confl icts
of interest, compliance with laws, and confi dentiality of proprietary information. The Red Book is reviewed on a
periodic basis with employees worldwide, and all employees are required to report suspected violations. A hotline
number is published in The Red Book to enable employees to report suspected violations anonymously. Employees
who report suspected violations are protected from discrimination or retaliation by the company. In addition to
The Red Book, the CEO, the COO, and all fi nancial management must sign a fi nancial code of ethics, which further
reinforces their fi duciary responsibilities.
The fi nancial statements have been audited by Ernst & Young LLP, an independent registered public accounting
fi rm. Their responsibility is to examine our consolidated fi nancial statements in accordance with generally accept-
ed auditing standards of the Public Company Accounting Oversight Board (United States). Ernst & Young’s opinion
with respect to the fairness of the presentation of the statements (see opinion on page 58) is included in our annual
report. Ernst & Young reports directly to the audit committee of the board of directors.
Our audit committee includes four nonemployee members of the board of directors, all of whom are indepen-
dent from our company. The committee charter, which is published in the proxy statement, outlines the members’
roles and responsibilities and is consistent with enacted corporate reform laws and regulations. It is the audit
committee’s responsibility to appoint an independent registered public accounting fi rm subject to shareholder
ratifi cation, approve both audit and nonaudit services performed by the independent registered public accounting
fi rm, and review the reports submitted by the fi rm. The audit committee meets several times during the year with
management, the internal auditors, and the independent public accounting fi rm to discuss audit activities, internal
controls, and fi nancial reporting matters, including reviews of our externally published fi nancial results. The inter-
nal auditors and the independent registered public accounting fi rm have full and free access to the committee.
We are dedicated to ensuring that we maintain the high standards of fi nancial accounting and reporting that
we have established. We are committed to providing fi nancial information that is transparent, timely, complete,
relevant, and accurate. Our culture demands integrity and an unyielding commitment to strong internal practices
and policies. Finally, we have the highest confi dence in our fi nancial reporting, our underlying system of internal
controls, and our people, who are objective in their responsibilities and operate under a code of conduct and the
highest level of ethical standards.
Management’s Report on Internal Control Over Financial Reporting—Eli Lilly and Company and Subsidiaries
Management of Eli Lilly and Company and subsidiaries is responsible for establishing and maintaining adequate
internal control over fi nancial reporting as defi ned in Rules 13a-15(f) and 15d-15(f) under the Securities Exchange
Act of 1934. We have global fi nancial policies that govern critical areas, including internal controls, fi nancial ac-
counting and reporting, fi duciary accountability, and safeguarding of corporate assets. Our internal accounting
control systems are designed to provide reasonable assurance that assets are safeguarded, that transactions are
executed in accordance with management’s authorization and are properly recorded, and that accounting records
are adequate for preparation of fi nancial statements and other fi nancial information. A staff of internal auditors
regularly monitors, on a worldwide basis, the adequacy and effectiveness of internal accounting controls. The
general auditor reports directly to the audit committee of the board of directors.
We conducted an evaluation of the effectiveness of our internal control over fi nancial reporting based on the
framework in Internal Control—Integrated Framework issued by the Committee of Sponsoring Organizations of the
Treadway Commission. Based on our evaluation under this framework, we concluded that our internal control over
fi nancial reporting were effective as of December 31, 2007. However, because of its inherent limitations, internal
control over fi nancial reporting may not prevent or detect misstatements. Also, projections of any evaluation of
effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in
conditions, or that the degree of compliance with the policies or procedures may deteriorate.
The internal control over fi nancial reporting has been assessed by Ernst & Young LLP. Their responsibility is to
evaluate whether internal control over fi nancial reporting was designed and operating effectively.
Sidney Taurel
Chairman of the Board and Chief Executive Offi cer
John C. Lechleiter, Ph.D.
President and Chief Operating Offi cer
Derica W. Rice
Senior Vice President and Chief Financial Offi cer
February 8, 2008
57
Report of Independent Registered Public Accounting Firm
Board of Directors and Shareholders
Eli Lilly and Company
We have audited the accompanying consolidated balance sheets of Eli Lilly and Company and subsidiaries as of
December 31, 2007 and 2006, and the related consolidated statements of income, cash fl ows, and comprehensive
income for each of the three years in the period ended December 31, 2007. These fi nancial statements are the
responsibility of the company’s management. Our responsibility is to express an opinion on these fi nancial state-
ments based on our audits.
We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board
(United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about
whether the fi nancial statements are free of material misstatement. An audit includes examining, on a test basis,
evidence supporting the amounts and disclosures in the fi nancial statements. An audit also includes assessing the
accounting principles used and signifi cant estimates made by management, as well as evaluating the overall fi nan-
cial statement presentation. We believe that our audits provide a reasonable basis for our opinion.
In our opinion, the fi nancial statements referred to above present fairly, in all material respects, the consoli-
dated fi nancial position of Eli Lilly and Company and subsidiaries at December 31, 2007 and 2006, and the consoli-
dated results of their operations and their cash fl ows for each of the three years in the period ended December 31,
2007, in conformity with U.S. generally accepted accounting principles.
We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board
(United States), the effectiveness of Eli Lilly and Company and subsidiaries’ internal control over fi nancial report-
ing as of December 31, 2007, based on criteria established in Internal Control—Integrated Framework issued by
the Committee of Sponsoring Organizations of the Treadway Commission and our report dated February 8, 2008
expressed an unqualifi ed opinion thereon.
As discussed in Note 2 to the fi nancial statements, in 2005 Eli Lilly and Company and subsidiaries adopted a
new accounting pronouncement for asset retirement obligations. As discussed in Note 12 to the fi nancial state-
ments, in 2006 Eli Lilly and Company and subsidiaries adopted a new accounting pronouncement for defi ned ben-
efi t pension and other postretirement plans. As discussed in Note 11 to the fi nancial statements, in 2007 Eli Lilly
and Company and subsidiaries adopted a new accounting pronouncement for income taxes.
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58
Report of Independent Registered Public Accounting Firm
Board of Directors and Shareholders
Eli Lilly and Company
We have audited Eli Lilly and Company and subsidiaries’ internal control over fi nancial reporting as of December
31, 2007, based on criteria established in Internal Control-Integrated Framework issued by the Committee of Spon-
soring Organizations of the Treadway Commission (the COSO criteria). Eli Lilly and Company and subsidiaries’
management is responsible for maintaining effective internal control over fi nancial reporting and for its assess-
ment of the effectiveness of internal control over fi nancial reporting included in the accompanying Management’s
Report on Internal Control Over Financial Reporting. Our responsibility is to express an opinion on the company’s
internal control over fi nancial reporting based on our audit.
We conducted our audit in accordance with the standards of the Public Company Accounting Oversight Board
(United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about
whether effective internal control over fi nancial reporting was maintained in all material respects. Our audit
included obtaining an understanding of internal control over fi nancial reporting, assessing the risk that a material
weakness exists, testing and evaluating the design and operating effectiveness of internal control based on the as-
sessed risk, and performing such other procedures as we considered necessary in the circumstances. We believe
that our audit provides a reasonable basis for our opinion.
A company’s internal control over fi nancial reporting is a process designed to provide reasonable assurance
regarding the reliability of fi nancial reporting and the preparation of fi nancial statements for external purposes in
accordance with generally accepted accounting principles. A company’s internal control over fi nancial reporting
includes those policies and procedures that (1) pertain to the maintenance of records that, in reasonable detail,
accurately and fairly refl ect the transactions and dispositions of the assets of the company; (2) provide reasonable
assurance that transactions are recorded as necessary to permit preparation of fi nancial statements in accor-
dance with generally accepted accounting principles, and that receipts and expenditures of the company are being
made only in accordance with authorizations of management and directors of the company; and (3) provide rea-
sonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the
company’s assets that could have a material effect on the fi nancial statements.
Because of its inherent limitations, internal control over fi nancial reporting may not prevent or detect mis-
statements. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that con-
trols may become inadequate because of changes in conditions, or that the degree of compliance with the policies
or procedures may deteriorate.
In our opinion, Eli Lilly and Company and subsidiaries maintained, in all material respects, effective internal
control over fi nancial reporting as of December 31, 2007, based on the COSO criteria.
We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board
(United States), the 2007 consolidated fi nancial statements of Eli Lilly and Company and subsidiaries and our re-
port dated February 8, 2008, expressed an unqualifi ed opinion thereon.
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59
Notice of 2008 Annual Meeting and Proxy Statement
March 10, 2008
Dear Shareholder:
You are cordially invited to attend our annual meeting of shareholders on Monday, April 21, 2008, at the Lilly Center
Auditorium, Lilly Corporate Center, Indianapolis, Indiana, at 11:00 a.m. EDT.
The notice of meeting and proxy statement that follow describe the business we will consider at the meeting.
Your vote is very important. I urge you to vote by mail, by telephone, or on the Internet in order to be certain your
shares are represented at the meeting, even if you plan to attend.
Please note our procedures for admission to the meeting described on page 63.
I look forward to seeing you at the meeting.
Sidney Taurel
Chairman of the Board and Chief Executive Offi cer
Important Notice Regarding the Availability of Proxy Materials for the Shareholder Meeting to be held April 21, 2008.
The annual report and proxy statement are available at http://www.lilly.com/investor/annual_report/lillyar2007.pdf
Notice of Annual Meeting of Shareholders
April 21, 2008
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The annual meeting of shareholders of Eli Lilly and Company will be held at the Lilly Center Auditorium, Lilly
Corporate Center, Indianapolis, Indiana, on Monday, April 21, 2008, at 11:00 a.m. EDT for the following purposes:
• to elect four directors of the company to serve three-year terms
• to ratify the appointment by the audit committee of Ernst & Young LLP as principal independent auditors for the
year 2008
• to approve amendments to the articles of incorporation to provide for the declassifi cation of the board of directors
• to approve amendments to the articles of incorporation to provide for election of directors by majority vote
• to amend the company’s 2002 Lilly Stock Plan
• to consider and vote on a shareholder proposal regarding the international outsourcing of animal research
• to consider and vote on a shareholder proposal requesting that the company amend its articles of incorporation
to allow shareholders to amend the company’s bylaws by majority vote
• to consider and vote on a shareholder proposal requesting that the board of directors adopt a simple majority
vote standard for certain matters other than the election of directors
• to consider and vote on a shareholder proposal requesting that the company prepare a semiannual report on its
political contributions.
Shareholders of record at the close of business on February 15, 2008, will be entitled to vote at the meeting
and at any adjournment of the meeting.
Attendance at the meeting will be limited to shareholders, those holding proxies from shareholders, and
invited guests from the media and fi nancial community. A page at the back of this proxy statement contains an
admission ticket. If you plan to attend the meeting, please bring this ticket with you.
This combined proxy statement and annual report to shareholders and the proxy are being mailed on or about
March 10, 2008.
By order of the board of directors,
James B. Lootens
Secretary
March 10, 2008
Indianapolis, Indiana
6060
General Information
Why did I receive this proxy statement?
The board of directors of Eli Lilly and Company is soliciting proxies to be voted at the annual meeting of sharehold-
ers (the annual meeting) to be held on Monday, April 21, 2008, and at any adjournment of the annual meeting. When
the company asks for your proxy, we must provide you with a proxy statement that contains certain information
specifi ed by law.
What will the shareholders vote on at the annual meeting?
Nine items:
• election of directors
• ratifi cation of the appointment of principal independent auditors
• amending the company’s articles of incorporation to provide for declassifi cation of the board
• amending the company’s articles of incorporation to provide for election of directors by majority vote
• amending the company’s stock plan
• a shareholder proposal on international outsourcing of animal research
• a shareholder proposal on allowing shareholders to amend the company’s bylaws
• a shareholder proposal on adopting a simple majority vote standard for matters other than election of directors
• a shareholder proposal requesting a semiannual report on the company’s political contributions.
Will there be any other items of business on the agenda?
We do not expect any other items of business because the deadline for shareholder proposals and nominations
has already passed. Nonetheless, in case there is an unforeseen need, the accompanying proxy gives discretion-
ary authority to the persons named on the proxy with respect to any other matters that might be brought before the
meeting. Those persons intend to vote that proxy in accordance with their best judgment.
Who is entitled to vote?
Shareholders as of the close of business on February 15, 2008 (the record date) may vote at the annual meeting.
You have one vote for each share of common stock you held on the record date, including shares:
• held directly in your name as the shareholder of record
• held for you in an account with a broker, bank, or other nominee
• attributed to your account in the Lilly Employee 401(k) Plan (the 401(k) plan).
What constitutes a quorum?
A majority of the outstanding shares, present or represented by proxy, constitutes a quorum for the annual meet-
ing. As of the record date, 1,136,985,018 shares of company common stock were issued and outstanding.
How many votes are required for the approval of each item?
There are differing vote requirements for the various proposals.
• The four nominees for director receiving the most votes will be elected. Abstentions and instructions to withhold
authority to vote for one or more of the nominees will result in those nominees receiving fewer votes but will not
count as votes against a nominee.
• The following items of business will be approved if the votes cast for the proposal exceed those cast against the
proposal:
—the appointment of principal independent auditors
—the management proposal to amend the articles of incorporation to provide for election of directors by
majority vote
—the management proposal to amend the company’s stock plan
—the shareholder proposals.
Abstentions will not be counted either for or against these proposals.
• The management proposal to amend the articles of incorporation to declassify the board requires the vote of
80 percent of the outstanding shares. For this item, abstentions and broker nonvotes have the same effect as a
vote against the proposal.
Broker nonvotes. If your shares are held by a broker, the broker will ask you how you want your shares to be voted.
If you give the broker instructions, your shares will be voted as you direct. If you do not give instructions, one of two
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things can happen, depending on the type of proposal. For the election of directors and the ratifi cation of auditors,
the broker may vote your shares in its discretion. For all other proposals, the broker may not vote your shares at
all. When that happens, it is called a “broker nonvote.”
How do I vote by proxy?
If you are a shareholder of record, you may vote your proxy by any one of the following methods.
By mail. Sign and date each proxy card you receive and return it in the prepaid envelope. Sign your name exactly as
it appears on the proxy. If you are signing in a representative capacity (for example, as an attorney-in-fact, execu-
tor, administrator, guardian, trustee, or the offi cer or agent of a corporation or partnership), please indicate your
name and your title or capacity. If the stock is held in custody for a minor (for example, under the Uniform Trans-
fers to Minors Act), the custodian should sign, not the minor. If the stock is held in joint ownership, one owner may
sign on behalf of all owners. If you return your signed proxy but do not indicate your voting preferences, we will
vote on your behalf for the election of the nominees for director listed below, for the ratifi cation of the appointment
of the independent auditors, for the management proposals on amending the articles of incorporation and amend-
ing the company’s stock plan, and against the shareholder proposals.
Note that if you previously elected to receive these materials electronically, you did not receive a proxy card.
If you wish to vote by mail, rather than by telephone or on the Internet as discussed below, you may request paper
copies of these materials, including a proxy card, by calling 317-433-5112. Please make sure you give us the control
number from the e-mail message that you received notifying you of the electronic availability of these materials,
along with your name and mailing address.
By telephone. Shareholders in the United States, Puerto Rico, and Canada may vote by telephone by following the
instructions on the enclosed proxy card or, if you received these materials electronically, by following the instruc-
tions in the e-mail message that notifi ed you of their availability. Voting by telephone has the same effect as voting
by mail. If you vote by telephone, do not return your proxy card. Telephone voting will be available until 11:59 p.m.
EDT, April 20, 2008.
On the Internet. You may vote online at www.proxyvote.com. Follow the instructions on the enclosed proxy card
or, if you received these materials electronically, follow the instructions in the e-mail message that notifi ed you
of their availability. Voting on the Internet has the same effect as voting by mail. If you vote on the Internet, do not
return your proxy card. Internet voting will be available until 11:59 p.m. EDT, April 20, 2008.
You have the right to revoke your proxy at any time before the meeting by (1) notifying the company’s secretary
in writing or (2) delivering a later-dated proxy by telephone, on the Internet, or by mail. If you are a shareholder of
record, you may also revoke your proxy by voting in person at the meeting.
How do I vote shares that are held by my broker?
If you have shares held by a broker or other nominee, you may instruct your broker or other nominee to vote your
shares by following instructions that the broker or nominee provides for you. Most brokers offer voting by mail,
telephone, and on the Internet.
How do I vote in person?
If you are a shareholder of record, you may vote your shares in person at the meeting. However, we encourage you
to vote by mail, by telephone, or on the Internet even if you plan to attend the meeting.
How do I vote my shares in the 401(k) plan?
You may instruct the plan trustee on how to vote your shares in the 401(k) plan by mail, by telephone, or on the
Internet as described above, except that, if you vote by mail, the card that you use will be a voting instruction card
rather than a proxy card.
How many shares in the 401(k) plan can I vote?
You may vote all the shares allocated to your account on the record date. In addition, unless you decline, your vote
will also apply to a proportionate number of other shares held in the 401(k) plan for which voting directions are not
received. These undirected shares include:
• shares credited to the accounts of participants who do not return their voting instructions (except for a small
number of shares from a prior stock ownership plan, which can be voted only on the directions of the participants
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to whose accounts the shares are credited)
• shares held in the plan that are not yet credited to individual participants’ accounts.
All participants are named fi duciaries under the terms of the 401(k) plan and under the Employee Retirement
Income Security Act (ERISA) for the limited purpose of voting shares credited to their accounts and the portion of
undirected shares to which their vote applies. Under ERISA, fi duciaries are required to act prudently in making vot-
ing decisions.
If you do not want to have your vote applied to the undirected shares, you should check the box marked “I de-
cline.” Otherwise, the trustee will automatically apply your voting preferences to the undirected shares proportion-
ally with all other participants who elected to have their votes applied in this manner.
What happens if I do not vote my 401(k) plan shares?
Your shares will be voted by other plan participants who have elected to have their voting preferences applied pro-
portionally to all shares for which voting instructions are not otherwise received.
What does it mean if I receive more than one proxy card?
It means that you hold shares in more than one account. To ensure that all your shares are voted, sign and return
each card. Alternatively, if you vote by telephone or on the Internet, you will need to vote once for each proxy card
and voting instruction card you receive.
Who tabulates the votes?
The votes are tabulated by an independent inspector of election, IVS Associates, Inc.
What should I do if I want to attend the annual meeting?
All shareholders as of the record date may attend by presenting the admission ticket that appears at the end of this
proxy statement. Please fi ll it out and bring it with you to the meeting. The meeting will be held at the Lilly Cen-
ter Auditorium. Please use the Lilly Center entrance to the south of the fountain at the intersection of Delaware
and McCarty streets. You will need to pass through security, including a metal detector. Present your ticket to the
usher at the meeting.
Parking will be available on a fi rst-come, fi rst-served basis in the garage indicated on the map on page 127.
If you have questions about admittance or parking, you may call 317-433-5112.
How do I contact the board of directors?
You may send written communications to one or more members of the board, addressed to:
Presiding Director, Board of Directors
Eli Lilly and Company
c/o Corporate Secretary
Lilly Corporate Center
Indianapolis, Indiana 46285
All such communications will be forwarded to the relevant director(s), except for solicitations or other matters
unrelated to the company.
How do I submit a shareholder proposal for the 2009 annual meeting?
The company’s 2009 annual meeting is scheduled for April 20, 2009. If a shareholder wishes to have a proposal
considered for inclusion in next year’s proxy statement, he or she must submit the proposal in writing so that we
receive it by November 10, 2008. Proposals should be addressed to the company’s corporate secretary, Lilly Cor-
porate Center, Indianapolis, Indiana 46285. In addition, the company’s bylaws provide that any shareholder wishing
to propose any other business at the annual meeting must give the company written notice by November 10, 2008.
That notice must provide certain other information as described in the bylaws. Copies of the bylaws are available
online at http://investor.lilly.com/bylaws.cfm.
Does the company offer an opportunity to receive future proxy materials electronically?
Yes. If you are a shareholder of record or a member of the 401(k) plan, you may, if you wish, receive future proxy
statements and annual reports online. If you elect this feature, you will receive an e-mail message notifying you
when the materials are available, along with a web address for viewing the materials and instructions for voting by
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telephone or on the Internet. If you have more than one account, you may receive separate e-mail notifi cations for
each account.
You may sign up for electronic delivery in two ways:
• If you vote online as described above, you may sign up for electronic delivery at that time.
• You may sign up at any time by visiting http://proxyonline.lilly.com.
If you received these materials electronically, you do not need to do anything to continue receiving materials
electronically in the future.
If you hold your shares in a brokerage account, you may also have the opportunity to receive proxy materials
electronically. Please follow the instructions of your broker.
What are the benefi ts of electronic delivery?
Electronic delivery reduces the company’s printing and mailing costs. It is also a convenient way for you to receive
your proxy materials and makes it easy to vote your shares online. If you have shares in more than one account, it
is an easy way to avoid receiving duplicate copies of proxy materials.
What are the costs of electronic delivery?
The company charges nothing for electronic delivery. You may, of course, incur the usual expenses associated with
Internet access, such as telephone charges or charges from your Internet service provider.
Can I change my mind later?
Yes. You may discontinue electronic delivery at any time. For more information, call 317-433-5112.
What is “householding”?
We have adopted “householding,” a procedure under which shareholders of record who have the same address
and last name and do not receive proxy materials electronically will receive only one copy of our annual report and
proxy statement unless one or more of these shareholders notifi es us that they wish to continue receiving individu-
al copies. This procedure saves printing and postage costs by reducing duplicative mailings.
Shareholders who participate in householding will continue to receive separate proxy cards. Householding
will not affect dividend check mailings.
Benefi cial shareholders can request information about householding from their banks, brokers, or other hold-
ers of record.
What if I want to receive a separate copy of the annual report and proxy statement?
If you participate in householding and wish to receive a separate copy of the 2007 annual report and 2008 proxy
statement, or if you wish to receive separate copies of future annual reports and proxy statements, please call
1-800-542-1061 or write to: Householding Department, 51 Mercedes Way, Edgewood, New York 11717. We will
deliver the requested documents to you promptly upon your request.
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Board of Directors
Directors’ Biographies
Class of 2008
The following fi ve directors’ terms will expire at this year’s annual meeting. Mr. Fisher will retire from the board at
the end of his current term. Each of the other directors in this class has been nominated and is standing for elec-
tion to serve a term that will expire in 2011. See page 102 of this proxy statement for more information.
Age 58
Director since 2008
Michael L. Eskew
Former Chairman and Chief Executive Offi cer, United Parcel Service, Inc.
Mr. Eskew served as chairman and chief executive offi cer of United Parcel Service, Inc., from
January 2002 until December 2007. He continues to serve on the UPS board of directors. Mr.
Eskew began his UPS career in 1972 as an industrial engineering manager and held various
positions of increasing responsibility, including time with UPS’s operations in Germany and with
UPS Airlines. In 1993, Mr. Eskew was named corporate vice president for industrial engineer-
ing. Two years later he became group vice president for engineering. In 1998, he was elected to
the UPS board of directors. In 1999, Mr. Eskew was named executive vice president and a year
later was given the additional title of vice chairman. Mr. Eskew serves as a trustee of the UPS
Foundation and as chairman of the board of trustees of the Annie E. Casey Foundation. He
also serves on the boards of 3M Corporation and IBM Corporation. He has been serving under
interim election since February 2008.
Director since 2000
George M.C. Fisher
Age 67
Former Chairman of the Board and Chief Executive Offi cer, Motorola, Inc. and Eastman
Kodak Company
Mr. Fisher served as chairman of the board of Eastman Kodak Company from 1993 to De-
cember 2000. He also served as chief executive offi cer from 1993 to January 2000 and as
president from 1993 to 1996. Prior to joining Kodak, he was an executive offi cer of Motorola,
Inc., serving as chairman and chief executive offi cer from 1990 to October 1993, and presi-
dent and chief executive offi cer from 1988 to 1990. Mr. Fisher is a senior advisor for Kohlberg
Kravis Roberts & Company, presiding director of General Motors Corporation, and a director
of Visant Corporation. He is a former chairman of PanAmSat Corporation and was chairman
of the National Academy of Engineering from 2000 to 2004.
Age 66
Director since 1995
Alfred G. Gilman, M.D., Ph.D.
Executive Vice President for Academic Affairs and Provost, The University of Texas South-
western Medical Center at Dallas; Dean, Southwestern Medical School; and Regental
Professor of Pharmacology and Director of the Cecil and Ida Green Center for Molecular,
Computational, and Systems Biology, The University of Texas Southwestern Medical Center
Dr. Gilman has served as executive vice president for academic affairs and provost of The
University of Texas Southwestern Medical Center at Dallas and dean of The University of
Texas Southwestern Medical School since 2005 and professor of pharmacology at The Uni-
versity of Texas Southwestern Medical Center since 1981. He holds the Raymond and Ellen
Willie Distinguished Chair of Molecular Neuropharmacology, the Nadine and Tom Craddick
Distinguished Chair in Medical Science, and the Atticus James Gill, M.D., Chair in Medical
Science at the university and was named a regental professor in 1995. Dr. Gilman was on
the faculty of the University of Virginia School of Medicine from 1971 to 1981 and was named
a professor of pharmacology there in 1977. He is a director of Regeneron Pharmaceuticals,
Inc. Dr. Gilman was a recipient of the Nobel Prize in Physiology or Medicine in 1994.
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Age 64
Director since 1987
Karen N. Horn, Ph.D.
Retired President, Private Client Services, and Managing Director, Marsh, Inc.
Ms . Horn served as president of Private Client Services and managing director of Marsh,
Inc ., a subsidiary of MMC, from 1999 until her retirement in 2003 . Prior to joining Marsh, she
was senior managing director and head of international private banking at Bankers Trust
Company; chair and chief executive officer of Bank One, Cleveland, N .A .; president of the
Federal Reserve Bank of Cleveland; treasurer of Bell Telephone Company of Pennsylvania;
and vice president of First National Bank of Boston . Ms . Horn serves as director of T . Rowe
Price Mutual Funds; The U .S . Russia Investment Fund, a presidential appointment; Simon
Property Group, Inc .; Norfolk Southern Corporation; and Fannie Mae . Ms . Horn has been
senior managing director of Brock Capital Group since 2004 .
Age 54
Director since 2005
John C. Lechleiter, Ph.D.
President and Chief Operating Officer
Dr . Lechleiter was named president and chief operating officer of the company in 2005, and on
April 1, 2008, he will become president and chief executive officer . He joined Lilly in 1979 as a
senior organic chemist and has held management positions in England and the U .S . He was
named vice president of pharmaceutical product development in 1993 and vice president of
regulatory affairs in 1994 . In 1996, he was named vice president for development and regula-
tory affairs . Dr . Lechleiter became senior vice president of pharmaceutical products in 1998,
and executive vice president of pharmaceutical products and corporate development in 2001 .
He was named executive vice president of pharmaceutical operations, in 2004 . He is a mem-
ber of the American Chemical Society . In 2004, Dr . Lechleiter was appointed to the Visiting
Committee of Harvard Business School and to the Health Policy and Management Execu-
tive Council of the Harvard School of Public Health . He also serves as a member of the board
of trustees of Xavier University (Cincinnati, Ohio) . In addition, he serves as a distinguished
advisor to The Children’s Museum of Indianapolis, a member of the board of directors and
executive committee of Fairbanks Institute, and a member of the United Way of Central Indiana
board of directors . He also serves on the board of Indianapolis Downtown, Inc .
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Class of 2009
The following four directors will continue in office until 2009, except for Mr . Taurel, who will resign from the board
effective December 31, 2008 .
Age 68
Director since 2002
Martin S. Feldstein, Ph.D.
President and Chief Executive Officer, National Bureau of Economic Research, and George
F. Baker Professor of Economics, Harvard University
Dr . Feldstein is president and chief executive officer of the National Bureau of Economic Re-
search and the George F . Baker Professor of Economics at Harvard University . He became
an assistant professor at Harvard in 1967, an associate professor in 1968, and a professor
in 1969 . From 1982 through 1984, he served as chairman of the Council of Economic Advis-
ers and President Ronald Reagan’s chief economic adviser . He is a member of the Ameri-
can Philosophical Society, a corresponding fellow of the British Academy, a fellow of the
Econometric Society, and a fellow of the National Association for Business Economics . Dr .
Feldstein is a member of the executive committee of the Trilateral Commission and a direc-
tor of American International Group, Inc .; the Council on Foreign Relations; and Economic
Studies, Inc . He is a member of the American Academy of Arts and Sciences and past presi-
dent of the American Economic Association .
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Age 48
Director since 2005
J. Erik Fyrwald
Group Vice President, DuPont Agriculture & Nutrition
Mr. Fyrwald has been group vice president of DuPont Agriculture & Nutrition since 2003. He
was previously vice president and general manager of DuPont’s nutrition and health busi-
nesses, which included The Solae Company, DuPont Qualicon, and Liqui-Box. Mr. Fyrwald
joined DuPont in 1981 as a production engineer, and held a variety of sales and management
positions in a number of areas. In 1990, he became the leader of the DuPont Engineering
Polymers and DuPont Butacite businesses for the Asia Pacifi c region, a position he held
until 1994. He was named leader of the DuPont Nylon Plastics business for the Americas
until 1996, when he became head of global sales and marketing for Engineering Polymers.
In 1998, he was appointed vice president of Corporate Plans and Business Development.
Mr. Fyrwald serves on the boards of CropLife International, the Des Moines Art Center, and
United Way of Iowa.
Age 61
Director since 2002
Ellen R. Marram
President, The Barnegat Group LLC
Ms. Marram is president of The Barnegat Group LLC, a fi rm that provides business advisory
services. She was a managing director at North Castle Partners, LLC from 2000 to 2005
and is currently an advisor to the fi rm. Prior to joining North Castle, she served as the chief
executive offi cer of a start-up B2B exchange for the food and beverage industry. From 1993
through 1998, Ms. Marram was president and chief executive offi cer of Tropicana and the
Tropicana Beverage Group. From 1988 to 1993, she was president and chief executive of-
fi cer of the Nabisco Biscuit Company, the largest operating unit of Nabisco, Inc.; from 1987
to 1988, she was president of Nabisco’s Grocery Division; and from 1970 to 1986, she held a
series of marketing positions at Nabisco/Standard Brands, Johnson & Johnson, and Lever
Brothers. Ms. Marram is a member of the board of directors of Ford Motor Company, The
New York Times Company, and Cadbury Schweppes plc as well as several private com-
panies. She serves on the boards of The New York-Presbyterian Hospital, Lincoln Center
Theater, Families and Work Institute, and Citymeals-on-Wheels.
Age 59
Director since 1991
Sidney Taurel
Chairman of the Board and Chief Executive Offi cer
Mr. Taurel has been the company’s chief executive offi cer since July 1998, and will retire
effective March 31, 2008. He has served as chairman of the board since January 1999, and
will retire as chairman and member of the board effective December 31, 2008. He served as
president and chief operating offi cer from February 1996 through September 2005. He joined
the company in 1971 and has held management positions in the company’s international
operations based in São Paulo, Vienna, Paris, and London. Mr. Taurel served as president of
Eli Lilly International Corporation from 1986 to 1991, executive vice president of the pharma-
ceutical division from 1991 to 1993, and executive vice president of the company from 1993
to 1996. He is a member of the boards of IBM Corporation and The McGraw-Hill Companies,
Inc. He is also a member of the executive committee of the board of directors of Pharmaceu-
tical Research and Manufacturers of America (PhRMA), a member of the board of overseers
of the Columbia Business School, a trustee at the Indianapolis Museum of Art, a director
of the Indianapolis Tennis Championships, and a member of The Business Council and The
Business Roundtable. In 2007, he was appointed to the President’s Advisory Committee for
Trade Policy and Negotiations. He is an offi cer of the French Legion of Honor.
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Class of 2010
The following four directors will continue in offi ce until 2010.
Age 66
Director since 2000
Sir Winfried Bischoff
Chairman, Citigroup Inc.
Sir Winfried Bischoff is chairman of Citigroup Inc. He served as chairman of Citigroup
Europe from 2000 to 2007 and as interim chief executive offi cer of Citigroup for a portion of
2007. From 1995 to 2000, he was chairman of Schroders plc. He joined the Schroder Group
in 1966 and held a number of positions there, including chairman of J. Henry Schroder & Co.
and group chief executive of Schroders plc. He is a non-executive director of The McGraw-
Hill Companies, Inc.; Land Securities plc, and Prudential plc.
;
Age 65
Director since 2005
J. Michael Cook
Retired Chairman and Chief Executive Offi cer, Deloitte & Touche LLP
Mr. Cook served as chairman and chief executive offi cer of Deloitte & Touche LLP from
1989 until his retirement in 1999. He joined Deloitte, Haskins & Sells in 1964 and served as
chairman and chief executive from 1986 through 1989. Mr. Cook is a member of the Advisory
Council of the Public Company Accounting Oversight Board and is a trustee of The Scripps
Research Institute. He serves on the boards of Comcast Corporation and International
Flavors & Fragrances Inc. He is chairman of the Accountability Advisory Council to the
Comptroller General of the United States. He was a member of the National Association of
Corporate Directors Blue Ribbon Panel on Corporate Governance and was named the 62nd
member of the Accounting Hall of Fame in 1999. He is past president of the Institute of Out-
standing Directors.
Director since 1995
Franklyn G. Prendergast, M.D., Ph.D.
Age 62
Edmond and Marion Guggenheim Professor of Biochemistry and Molecular Biology and
Professor of Molecular Pharmacology and Experimental Therapeutics, Mayo Medical
School; Director, Mayo Clinic Center for Individualized Medicine; and Director Emeritus,
Mayo Clinic Cancer Center
Dr. Prendergast is the Edmond and Marion Guggenheim Professor of Biochemistry and
Molecular Biology and Professor of Molecular Pharmacology and Experimental Thera-
peutics at Mayo Medical School and the director of the Center for Individualized Medicine.
He has held several other teaching positions at the Mayo Medical School since 1975. Dr.
Prendergast serves on the board of trustees of the Mayo Foundation and the Mayo Clinic
Board of Governors.
Age 58
Director since 1995
Kathi P. Seifert
Retired Executive Vice President, Kimberly-Clark Corporation
Ms. Seifert served as executive vice president for Kimberly-Clark Corporation until June
2004. She joined Kimberly-Clark in 1978 and served in several capacities in connection with
both the domestic and international consumer products businesses. Prior to joining Kimber-
ly-Clark, Ms. Seifert held management positions at Procter & Gamble, Beatrice Foods, and
Fort Howard Paper Company. She is chairman of Pinnacle Perspectives, LLC. Ms. Seifert
serves on the boards of Supervalu Inc.; Revlon Consumer Products Corporation; Lexmark
International, Inc.; Appleton Papers Inc.; the U.S. Fund for UNICEF; ThedaCare; and the Fox
Cities Performing Arts Center.
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Highlights of the Company’s Corporate Governance Guidelines
The board of directors has established guidelines that it follows in matters of corporate governance. The following
summary provides highlights of those guidelines. A complete copy of the guidelines is available online at
http://investor.lilly.com/guidelines.cfm or in paper form upon request to the company’s corporate secretary.
I. Role of the Board
The directors are elected by the shareholders to oversee the actions and results of the company’s management.
Their responsibilities include:
• providing general oversight of the business
• approving corporate strategy
• approving major management initiatives
• providing oversight of legal and ethical conduct
• overseeing the company’s management of signifi cant business risks
• selecting, compensating, and evaluating directors
• evaluating board processes and performance
• selecting, compensating, evaluating, and, when necessary, replacing the chief executive offi cer, and
compensating other executive offi cers
• ensuring that a succession plan is in place for all senior executives.
II. Composition of the Board
Mix of Independent Directors and Offi cer-Directors
There should always be a substantial majority (75 percent or more) of independent directors. The chief executive
offi cer should be a board member. Other offi cers may, from time to time, be board members, but no offi cer other
than the chief executive offi cer should expect to be elected to the board by virtue of his or her offi ce.
Selection of Director Candidates
The board is responsible for selecting candidates for board membership and for establishing the criteria to be
used in identifying potential candidates. The board delegates the screening process to the directors and corporate
governance committee. For more information on the director nomination process, including the current selection
criteria, see Directors and Corporate Governance Committee Matters on pages 77–78.
Independence Determinations
The board annually determines the independence of directors based on a review by the directors and corporate
governance committee. No director is considered independent unless the board has determined that he or she has
no material relationship with the company, either directly or as a partner, shareholder, or offi cer of an organization
that has a material relationship with the company. Material relationships can include commercial, industrial, bank-
ing, consulting, legal, accounting, charitable, and familial relationships, among others. To evaluate the materiality
of any such relationship, the board has adopted categorical independence standards consistent with the New York
Stock Exchange listing guidelines.
Specifi cally, a director is not considered independent if (i) the director or an immediate family member is a
current partner of Lilly’s independent auditor (currently Ernst & Young LLP); (ii) the director is a current employee
of such fi rm; (iii) the director has an immediate family member who is a current employee of such fi rm and who
participates in the fi rm’s audit, assurance, or tax compliance (but not tax planning) practice; or (iv) the director or
an immediate family member was within the last three years (but is no longer) a partner or employee of such fi rm
and personally worked on the listed company’s audit within that time.
In addition, a director is not considered independent if any of the following relationships existed within the
previous three years:
• a director who is an employee of Lilly, or whose immediate family member is an executive offi cer of Lilly.
Temporary service by an independent director as interim chairman or chief executive offi cer will not disqualify
the director from being independent following completion of that service.
• a director who receives any direct compensation from Lilly other than the director’s normal director
compensation, or whose immediate family member receives more than $100,000 per year in direct
compensation from Lilly other than for service as a non-executive employee.
• a director who is employed (or whose immediate family member is employed as an executive offi cer) by another
company where any Lilly executive offi cer serves on the compensation committee of that company’s board.
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• a director who is employed by, who is a 10 percent shareholder of, or whose immediate family member is an
executive offi cer of a company that makes payments to or receives payments from Lilly for property or services
that exceed the greater of $1 million or 2 percent of that company’s gross revenues in a single fi scal year.
• a director who is an executive offi cer of a nonprofi t organization that receives grants or contributions from Lilly
in a single fi scal year exceeding the greater of $1 million or 2 percent of that organization’s gross revenues in a
single fi scal year.
Members of the audit, compensation, and directors and corporate governance committees must meet all ap-
plicable independence tests of the New York Stock Exchange, Securities and Exchange Commission, and Internal
Revenue Service.
In February 2008, the directors and corporate governance committee reviewed directors’ responses to a
questionnaire asking about their relationships with the company (and those of their immediate family members)
and other potential confl icts of interest, as well as material provided by management related to transactions,
relationships, or arrangements between the company and the directors or parties related to the directors. The
committee determined that all 11 nonemployee directors listed below are independent, and that the members of
the audit, compensation, and directors and corporate governance committees also meet the independence tests
referenced above. The committee recommended this conclusion to the board and explained the basis for its deci-
sion, and this conclusion was adopted by the full board. The committee and the board determined that none of the
11 directors listed below has had during the last three years (i) any of the relationships listed above or (ii) any other
material relationship with the company that would compromise his or her independence. The table below includes
a description of categories or types of transactions, relationships, or arrangements considered by the board (in
addition to those listed above) in reaching its determination that the directors are independent. All of these rela-
tionships and transactions were entered into at arm’s length in the normal course of business and, to the extent
they are commercial relationships, have standard commercial terms. None of these relationships or transactions
exceeded the thresholds described above or otherwise compromise the independence of the named director.
Name
Independent Transactions/Relationships/Arrangements
Sir Winfried Bischoff
Mr. Cook
Mr. Eskew
Dr. Feldstein
Mr. Fisher
Mr. Fyrwald
Dr. Gilman
Ms. Horn
Ms. Marram
Dr. Prendergast
Ms. Seifert
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Commercial banking, capital markets, and indenture trustee relationships between Lilly and various Citigroup
banks—immaterial
None
Lilly’s purchase of shipping, courier, and post offi ce box services from UPS—immaterial
Lilly grants and contributions to Harvard University and the National Bureau of Economic Research—immaterial
None
Lilly’s purchase of DuPont products and services—immaterial
Lilly grants and contributions to the University of Texas Southwestern Medical Center—immaterial
None
None
Lilly grants and contributions to Mayo Clinic and Mayo Foundation—immaterial
None
Director Tenure
Subject to the company’s charter documents, the governance guidelines establish the following expectations for
director tenure:
• A company offi cer-director, including the chief executive offi cer, will resign from the board at the time he or she
retires or otherwise ceases to be an active employee of the company. Mr. Taurel will remain an employee and
continue his service on the board through the end of 2008.
• Nonemployee directors will retire from the board not later than the annual meeting of shareholders that follows
their seventy-second birthday.
• Directors may stand for reelection even though the board’s retirement policy would prevent them from
completing a full three-year term.
• A nonemployee director who retires or changes principal job responsibilities will offer to resign from the board.
The directors and corporate governance committee will assess the situation and recommend to the board
whether to accept the resignation.
Voting for Directors
In an uncontested election, any nominee for director who receives a greater number of votes “withheld” from his or
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her election than votes “for” such election (a “majority withheld vote”) shall promptly tender his or her resignation
following certifi cation of the shareholder vote. The directors and corporate governance committee will consider
the resignation offer and recommend to the board whether to accept it. The board will act on the committee’s rec-
ommendation within 90 days following certifi cation of the shareholder vote. Board action on the matter will require
the approval of a majority of the independent directors.
The company will disclose the board’s decision on a Form 8-K furnished to the Securities and Exchange
Commission within four business days after the decision, including a full explanation of the process by which the
decision was reached and, if applicable, the reasons why the board rejected the director’s resignation. If the resig-
nation is accepted, the directors and corporate governance committee will recommend to the board whether to fi ll
the vacancy or reduce the size of the board.
Any director who tenders his or her resignation under this provision will not participate in the committee or
board deliberations regarding whether to accept the resignation offer. If each member of the directors and corpo-
rate governance committee receives a majority withheld vote at the same election, then the independent directors
who did not receive a majority withheld vote will appoint a committee amongst themselves to consider the resigna-
tion offers and recommend to the board whether to accept them.
See Item 4 for management’s proposal to provide for the election of directors by a true majority vote.
III. Director Compensation and Equity Ownership
The directors and corporate governance committee annually reviews board compensation. Any recommendations
for changes are made to the full board by the committee.
Directors should hold meaningful equity ownership positions in the company; accordingly, a signifi cant portion of
overall director compensation is in the form of company equity. Directors are required to hold Lilly stock valued at a
minimum of fi ve times their annual cash retainer; new directors are allowed fi ve years to reach this ownership level.
IV. Key Responsibilities of the Board
Selection of Chairman and Chief Executive Offi cer; Succession Planning
The board customarily combines the roles of chairman and chief executive offi cer, believing this generally provides
the most effi cient and effective leadership model for the company. The board anticipates that, in certain circum-
stances, and particularly during relatively short periods of leadership transition, these roles may be assigned to
two different persons. The presiding director recommends to the board an appropriate process by which a new
chairman and chief executive offi cer will be selected.
The independent directors are responsible for overseeing succession and management development pro-
grams for senior leadership. The chief executive offi cer develops and maintains a process for advising the board on
succession planning for the chief executive offi cer and other key leadership positions. He or she reviews this plan
with the independent directors at least annually.
Evaluation of Chief Executive Offi cer
The presiding director leads the independent directors annually in assessing the performance of the chief execu-
tive offi cer. The results of this review are discussed with the chief executive offi cer and considered by the compen-
sation committee in establishing his or her compensation for the next year.
Corporate Strategy
Once each year, the board devotes an extended meeting to an update from management regarding the strategic is-
sues and opportunities facing the company, allowing the board an opportunity to provide direction for the corporate
strategic plan. Throughout the year, signifi cant corporate strategy decisions are brought to the board for approval.
Code of Ethics
The board approved the company’s code of ethics, which complies with the requirements of the New York Stock
Exchange and the Securities and Exchange Commission. This code is set out in:
• The Red Book, a comprehensive code of ethical and legal business conduct applicable to all employees
worldwide and to our board of directors
• the company’s Code of Ethical Conduct for Lilly Financial Management, a supplemental code for our chief executive
offi cer, chief operating offi cer, and all members of fi nancial management that recognizes the unique responsibilities
of those individuals in assuring proper accounting, fi nancial reporting, internal controls, and fi nancial stewardship.
Both documents are available online at http://investor.lilly.com/code_business_conduct.cfm or in paper form
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upon request to the company’s corporate secretary.
The audit committee and public policy and compliance committee assist in the board’s oversight of compliance
programs with respect to matters covered in the code of ethics.
V. Functioning of the Board
Executive Session of Directors
The independent directors meet alone in executive session at every regularly scheduled board meeting. In addition,
at least twice a year, the independent directors meet in executive session with the chief executive offi cer.
Presiding Director
The board appoints a presiding director from among the independent directors (currently Ms. Horn). The presiding
director:
• leads the board’s process for selecting and evaluating the chief executive offi cer;
• presides at all meetings of the board at which the chairman is not present, including executive sessions of
the independent directors unless the directors decide that, due to the subject matter of the session, another
independent director should preside;
• serves as a liaison between the chairman and the independent directors;
• approves meeting agendas and schedules and generally approves information sent to the board; and
• has the authority to call meetings of the independent directors.
Confl icts of Interest
Occasionally a director’s business or personal relationships may give rise to an interest that confl icts, or appears
to confl ict, with the interests of the company. Directors must disclose to the company all relationships that cre-
ate a confl ict or an appearance of a confl ict. The board, after consultation with counsel, takes appropriate steps
to ensure that all directors voting on an issue are disinterested. In appropriate cases, the affected director will be
excused from discussions on the issue.
To avoid any confl ict or appearance of a confl ict, board decisions on certain matters of corporate governance
are made solely by the independent directors. These include executive compensation and the selection, evaluation,
and removal of the chief executive offi cer.
Review and Approval of Transactions with Related Persons
The board has adopted a written policy and written procedures for review, approval, and monitoring of transac-
tions involving the company and “related persons” (directors and executive offi cers, their immediate family mem-
bers, or shareholders owning fi ve percent or greater of the company’s outstanding stock). The policy covers any
related-person transaction that meets the minimum threshold for disclosure in the proxy statement under the
relevant SEC rules (generally, transactions involving amounts exceeding $120,000 in which a related person has
a direct or indirect material interest).
Policy
• Related-person transactions must be approved by the board or by a committee of the board consisting solely
of independent directors, who will approve the transaction only if they determine that it is in the best interests
of the company. In considering the transaction, the board or committee will consider all relevant factors,
including as applicable (i) the company’s business rationale for entering into the transaction; (ii) the alternatives
to entering into a related-person transaction; (iii) whether the transaction is on terms comparable to those
available to third parties, or in the case of employment relationships, to employees generally; (iv) the potential
for the transaction to lead to an actual or apparent confl ict of interest and any safeguards imposed to prevent
such actual or apparent confl icts; and (v) the overall fairness of the transaction to the company.
• The board or relevant committee will periodically monitor the transaction to ensure that there are no changed
circumstances that would render it advisable for the company to amend or terminate the transaction.
Procedures
• Management or the affected director or executive offi cer will bring the matter to the attention of the chairman,
the presiding director, the chair of the directors and corporate governance committee, or the secretary.
• The chairman and the presiding director shall jointly determine (or, if either is involved in the transaction, the
other shall determine in consultation with the chair of the directors and corporate governance committee)
whether the matter should be considered by the board or by one of its existing committees consisting only of
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independent directors.
• If a director is involved in the transaction, he or she will be recused from all discussions and decisions about the
transaction.
• The transaction must be approved in advance whenever practicable, and if not practicable, must be ratifi ed as
promptly as practicable.
• The board or relevant committee will review the transaction annually to determine whether it continues to be in
the company’s best interests.
Currently the only related-person transaction is the time-share arrangement for Mr. Taurel’s personal use
of the corporate aircraft, as described on pages 100–101. The compensation committee approved and continues to
monitor this arrangement consistent with the above policy.
Orientation and Continuing Education
A comprehensive orientation process is in place for new directors. In addition, directors receive ongoing continuing
education through educational sessions at meetings, the annual strategy retreat, and periodic mailings between
meetings. We hold periodic mandatory training sessions for the audit committee, to which other directors and ex-
ecutive offi cers are invited. We also afford directors the opportunity to attend external director education programs.
Director Access to Management and Independent Advisers
Independent directors have direct access to members of management whenever they deem it necessary. The inde-
pendent directors and the committees are also free to retain their own independent advisers, at company expense,
whenever they feel it would be desirable to do so. In accordance with New York Stock Exchange listing standards,
the audit, compensation, and directors and corporate governance committees have sole authority to retain inde-
pendent advisers to their respective committees.
Assessment of Board Processes and Performance
The directors and corporate governance committee annually assesses the performance of the board, its commit-
tees, and board processes based on inputs from all directors. The committee also considers the contributions of
individual directors at least every three years when considering whether to recommend nominating the director to
a new three-year term.
VI. Board Committees
Number, Structure, and Independence
The duties and membership of the six board-appointed committees are described below. Only independent direc-
tors may serve on the audit, compensation, directors and corporate governance, and public policy and compliance
committees. Only independent directors may chair any committee.
Committee membership and selection of committee chairs are recommended to the board by the directors
and corporate governance committee after consulting the chairman of the board and after considering the desires
of the board members.
Functioning of Committees
Each committee reviews and approves its own charter annually, and the directors and corporate governance com-
mittee reviews and approves all committee charters annually. The board may form new committees or disband
a current committee (except the audit, compensation, and directors and corporate governance committees) as it
deems appropriate. The chair of each committee determines the frequency and agenda of committee meetings.
In addition, the audit and compensation committees meet alone in executive session on a regular basis; all other
committees meet in executive session as needed.
All six committee charters are available online at http://investor.lilly.com/board-committees.cfm or in paper
form upon request to the company’s corporate secretary.
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Committees of the Board of Directors
Audit Committee
The duties of the audit committee are described in the audit committee report found on page 78.
Directors and Corporate Governance Committee
The duties of the directors and corporate governance committee are described on page 77.
Compensation Committee
The duties of the compensation committee are described on page 80, and the compensation committee report is
shown on pages 90–91.
Public Policy and Compliance Committee
• oversees the processes by which the company conducts its business so that the company will do so in a manner
that complies with laws and regulations and refl ects the highest standards of integrity
• reviews and makes recommendations regarding policies, practices, and procedures of the company that relate
to public policy and social, political, and economic issues that may affect the company.
Finance Committee
• reviews and makes recommendations regarding capital structure and strategies, including dividends, stock
repurchases, capital expenditures, fi nancings and borrowings, and signifi cant business development projects.
Science and Technology Committee
• reviews and makes recommendations regarding the company’s strategic research goals and objectives
• reviews new developments, technologies, and trends in pharmaceutical research and development.
Membership and Meetings of the Board and Its Committees
In 2007, each director attended more than 88 percent of the total number of meetings of the board and the com-
mittees on which he or she serves. In addition, all board members are expected to attend the annual meeting of
shareholders, and all attended in 2007. Current committee membership and the number of meetings of the full
board and each committee in 2007 are shown in the table below.
Name
Sir Winfried Bischoff
Mr. Cook
Mr. Eskew
Dr. Feldstein
Mr. Fisher
Mr. Fyrwald
Dr. Gilman
Ms. Horn
Dr. Lechleiter
Ms. Marram
Dr. Prendergast
Ms. Seifert
Mr. Taurel
Board
Member
Member
Member
Member
Member
Member
Member
Member
Member
Member
Member
Member
Chair
Chair
Member
Member
Member
Member
Audit
Compensation
Directors and
Corporate
Governance
Member
Finance
Chair
Member
Public
Policy and
Compliance
Science and
Technology
Member
Member
Member
Member
Chair
Member
Member
Chair
Member
Member
Chair
Member
Member
Member
Member
Chair
Member
Member
Number of 2007 Meetings
7
8
6
4
5
5
5
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Directors’ Compensation
Directors who are employees receive no additional compensation for serving on the board or its committees.
In 2007, we provided the following annual compensation to directors who are not employees:
Name
Sir Winfried Bischoff
Mr. Cook
Dr. Feldstein
Mr. Fisher
Mr. Fyrwald
Dr. Gilman
Ms. Horn
Ms. Marram
Dr. Prendergast
Ms. Seifert
Fees Earned
or Paid in Cash ($) 1
Stock Awards
($) 2
Stock Option Awards
($) 3
All Other Compensation
($) 4
$95,000
$120,000
$110,000
$93,000
$103,000
$100,000
$122,000
$95,000
$98,000
$100,000
$145,000
$145,000
$145,000
$145,000
$145,000
$145,000
$145,000
$145,000
$145,000
$145,000
$4,074
0
$4,074
$4,074
0
$4,074
$4,074
$4,074
$4,074
$4,074
$3,067
$29,124
$29,000
$30,610
$1,185
$32,374
$4,202
$34,878
$555
$75,000
Total
($) 5
$247,141
$294,124
$288,074
$272,684
$249,185
$281,448
$275,276
$278,952
$247,629
$324,074
1 The following directors deferred 2007 cash compensation into their deferred share account under the Lilly Direc-
tors’ Deferral Plan (further described below):
Name
Mr. Fisher
Mr. Fyrwald
2007 Cash Deferred
$46,500
$103,000
Shares
839
1,854
2 Each nonemployee director received an award of stock with a grant date fair value of $145,000 (2,840 shares).
This stock award and all prior stock awards are fully vested in that they are not subject to forfeiture; however, the
shares are not issued until the director ends his or her service on the board, as further described below under
“Lilly Directors’ Deferral Plan.” The table shows the expense recognized by the company for each director’s stock
award.
3 No stock options were granted in 2007, as the stock option program for directors was discontinued in 2005. The
amounts in this column refl ect the expenses related to options granted in 2004 recognized in our 2007 fi nan-
cial statements. A discussion of the assumption used in calculating these values may be found in Note 7 to our
2007 audited fi nancial statements on pages 43–44 of our annual report. Aggregate total numbers of stock option
awards outstanding are shown below in the Directors’ Outstanding Stock Options table. All outstanding options
were vested as of February 17, 2007. Stock option grants were established using the same procedure for timing
and price as is used for employees.
4 This column includes amounts donated by the Eli Lilly and Company Foundation, Inc. under its matching gift
program, which is generally available to U.S. employees as well as the outside directors. Under this program,
the foundation matches 100 percent of charitable donations over $25 made to eligible charities, up to a maximum
of $90,000 per year for each individual. For all directors, the amounts in this column also include tax reimburse-
ments for income imputed to him or her for use of the corporate aircraft, or for commercial fl ights, by his or her
spouse to attend board functions that included spouse participation. For Mr. Fyrwald, this amount includes tax re-
imbursement for income imputed to him for child care during a board function that included spouse participation.
The foundation matched the following donations of more than $10,000 for outside directors in 2007 via pay-
ments made directly to the recipient charity:
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Mr. Cook
Dr. Feldstein
Mr. Fisher
Dr. Gilman
Ms. Marram
Ms. Seifert
Amount of Matching Donation
$27,000
$29,000
$30,000
$31,500
$34,500
$75,000
5 Directors do not participate in a Lilly pension plan or non-equity incentive plan.
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Directors’ Outstanding Stock Options
Name
Sir Winfried Bischoff
Mr. Cook
Mr. Eskew
Dr. Feldstein
Mr. Fisher
Mr. Fyrwald
Dr. Gilman
Ms. Horn
Ms. Marram
Dr. Prendergast
Ms. Seifert
Grant Date
2/20/2001
2/19/2002
2/18/2003
2/17/2004
—
—
2/19/2002
2/18/2003
2/17/2004
2/20/2001
2/19/2002
2/18/2003
2/17/2004
—
4/20/2000
2/20/2001
2/19/2002
2/18/2003
2/17/2004
4/20/2000
2/20/2001
2/19/2002
2/18/2003
2/17/2004
2/18/2003
2/17/2004
4/20/2000
2/20/2001
2/19/2002
2/18/2003
2/17/2004
4/20/2000
2/20/2001
2/19/2002
2/18/2003
2/17/2004
Expiration Date
Exercise Price
Outstanding Stock Options
(Exercisable)
2/18/2011
2/17/2012
2/18/2013
2/17/2014
—
—
2/17/2012
2/18/2013
2/17/2014
2/18/2011
2/17/2012
2/18/2013
2/17/2014
—
4/19/2010
2/18/2011
2/17/2012
2/18/2013
2/17/2014
4/19/2010
2/18/2011
2/17/2012
2/18/2013
2/17/2014
2/18/2013
2/17/2014
4/19/2010
2/18/2011
2/17/2012
2/18/2013
2/17/2014
4/19/2010
2/18/2011
2/17/2012
2/18/2013
2/17/2014
$73.98
$75.92
$57.85
$73.11
—
—
$75.92
$57.85
$73.11
$73.98
$75.92
$57.85
$73.11
—
$75.94
$73.98
$75.92
$57.85
$73.11
$75.94
$73.98
$75.92
$57.85
$73.11
$57.85
$73.11
$75.94
$73.98
$75.92
$57.85
$73.11
$75.94
$73.98
$75.92
$57.85
$73.11
2,800
2,800
2,800
2,800
0
0
2,800
2,800
2,800
2,800
2,800
2,800
2,800
0
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
2,800
Cash Compensation
The company provides directors the following cash compensation:
• retainer of $80,000 per year (payable monthly)
• $1,000 for each committee meeting attended
• $2,000 to the committee chairpersons for each committee meeting conducted as compensation for the
chairperson’s preparation time
• retainer of $20,000 per year to the presiding director
• reimbursement for customary and usual travel expenses.
Stock Compensation
Stock compensation for directors consists of:
• shares of Lilly stock equaling $145,000, deposited annually in a deferred share account in the Lilly Directors’
Deferral Plan (as described below), payable after service on the board has ended.
Lilly Directors’ Deferral Plan
This plan allows directors to defer receipt of all or part of their retainer and meeting fees until after their service
on the board has ended. Each director can choose to invest the funds in either of two accounts:
• Deferred Share Account. This account allows the director, in effect, to invest his or her deferred cash
compensation in Lilly stock. In addition, the annual award of shares to each director noted above (2,840 shares
in 2007) is credited to this account on a pre-set annual date. Funds in this account are credited as hypothetical
shares of Lilly stock based on the market price of the stock at the time the compensation would otherwise have
been earned. Hypothetical dividends are “reinvested” in additional shares based on the market price of the stock
on the date dividends are paid. All shares in the deferred share accounts are hypothetical and are not issued or
transferred until the director ends his or her service on the board.
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• Deferred Compensation Account. Funds in this account earn interest each year at a rate of 120 percent of the
applicable federal long-term rate, compounded monthly, as established the preceding December by the U.S.
Treasury Department under Section 1274(d) of the Internal Revenue Code. The rate for 2008 is 5.5 percent.
The aggregate amount of interest that accrued in 2007 for the participating directors was $188,706, at a rate of
5.7 percent.
Both accounts may be paid in a lump sum or in annual installments for up to 10 years. Amounts in the deferred
share account are paid in shares of Lilly stock.
Directors and Corporate Governance Committee Matters
Overview
The directors and corporate governance committee recommends candidates for membership on the board and
board committees. The committee also oversees matters of corporate governance, director independence, direc-
tor compensation, and board performance. The committee’s charter is available online at http://investor.lilly.
com/board-committees.cfm or in paper form upon request to the company’s corporate secretary.
All committee members are independent as defi ned in the New York Stock Exchange listing requirements.
Director Nomination Process
The board seeks independent directors who represent a mix of backgrounds and experiences that will enhance the
quality of the board’s deliberations and decisions. Candidates shall have substantial experience with one or more pub-
licly traded national or multinational companies or shall have achieved a high level of distinction in their chosen fi elds.
Board membership should refl ect diversity in its broadest sense, including persons diverse in geography, gen-
der, and ethnicity. The board is particularly interested in maintaining a mix that includes the following backgrounds:
• active or retired chief executive offi cers and senior executives, particularly those with experience in
operations, fi nance or banking, and marketing or sales
• international business
• medicine and science
• government and public policy
• health care environment
• information technology.
The board delegates the screening process to the directors and corporate governance committee, which
receives direct input from other board members. Potential candidates are identifi ed by recommendations from
several sources, including:
• incumbent directors
• management
• shareholders
• an independent executive search fi rm retained by the committee to assist in locating candidates meeting the
board’s selection criteria.
The committee employs the same process for evaluating all candidates, including those submitted by share-
holders. The committee initially evaluates the candidate based on publicly available information and any additional
information supplied by the party recommending the candidate. If the candidate appears to satisfy the selection
criteria and the committee’s initial evaluation is favorable, the committee, assisted by management, gathers ad-
ditional data on the candidate’s qualifi cations, availability, probable level of interest, and any potential confl icts
of interest. If the committee’s subsequent evaluation continues to be favorable, the candidate is contacted by the
chairman of the board and one or more of the independent directors for direct discussions to determine the mutual
levels of interest in pursuing the candidacy. If these discussions are favorable, the committee makes a fi nal recom-
mendation to the board to nominate the candidate for election by the shareholders (or to select the candidate to fi ll
a vacancy, as applicable). Mr. Eskew, who is standing for election, was referred to the committee by Mr. Taurel.
Process for Submitting Recommendations and Nominations
A shareholder who wishes to recommend a director candidate for evaluation by the committee pursuant to this
process should forward the candidate’s name and information about the candidate’s qualifi cations to the chairman
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of the directors and corporate governance committee, in care of the corporate secretary, at Lilly Corporate Center,
Indianapolis, Indiana 46285. The candidate must meet the selection criteria described above and must be willing
and expressly interested in serving on the board.
Under Section 1.9 of the company’s bylaws, a shareholder who wishes to directly nominate a director candidate
at the 2009 annual meeting (i.e., to propose a candidate for election who is not otherwise nominated by the board
through the recommendation process described above) must give the company written notice by November 10, 2008.
The notice should be addressed to the corporate secretary at Lilly Corporate Center, Indianapolis, Indiana 46285. The
notice must contain prescribed information about the candidate and about the shareholder proposing the candidate
as described in more detail in Section 1.9 of the bylaws. A copy of the bylaws is available online at http://investor.lilly.
com/bylaws.cfm. The bylaws will also be provided by mail without charge upon request to the corporate secretary.
Audit Committee Matters
Audit Committee Membership
All members of the audit committee are independent as defi ned in the New York Stock Exchange listing standards
applicable to audit committee members. The board of directors has determined that Mr. J. Michael Cook is an audit
committee fi nancial expert as defi ned in the rules of the Securities and Exchange Commission.
Audit Committee Report
The audit committee (“we” or “the committee”) reviews the company’s fi nancial reporting process on behalf of the
board. Management has the primary responsibility for the fi nancial statements and the reporting process, includ-
ing the systems of internal controls and disclosure controls. In this context, we have met and held discussions with
management and the independent auditors. Management represented to us that the company’s consolidated fi nancial
statements were prepared in accordance with generally accepted accounting principles, and we have reviewed and
discussed the audited fi nancial statements and related disclosures with management and the independent auditors,
including a review of the signifi cant management judgments underlying the fi nancial statements and disclosures.
The independent auditors report to us. We have sole authority to appoint (subject to shareholder ratifi cation)
and to terminate the engagement of the independent auditors.
We have discussed with the independent auditors matters required to be discussed by Statement on Auditing
Standards No. 61 (Communication with Audit Committees), including the quality, not just the acceptability, of the ac-
counting principles, the reasonableness of signifi cant judgments, and the clarity of the disclosures in the fi nancial
statements. In addition, we have received the written disclosures and the letter from the independent auditors re-
quired by the Independence Standards Board Standard No. 1 (Independence Discussions with Audit Committees) and
have discussed with the independent auditors the auditors’ independence from the company and its management. In
concluding that the auditors are independent, we determined, among other things, that the nonaudit services provid-
ed by Ernst & Young LLP (as described below) were compatible with their independence. Consistent with the require-
ments of the Sarbanes-Oxley Act of 2002, we have adopted policies to avoid compromising the independence of the
independent auditors, such as prior committee approval of nonaudit services and required audit partner rotation.
We discussed with the company’s internal and independent auditors the overall scope and plans for their
respective audits including internal control testing under Section 404 of the Sarbanes-Oxley Act. We periodically
meet with the internal and independent auditors, with and without management present, and in private sessions
with members of senior management (such as the chief fi nancial offi cer and the chief accounting offi cer) to discuss
the results of their examinations, their evaluations of the company’s internal controls, and the overall quality of the
company’s fi nancial reporting. We also periodically meet in executive session.
In reliance on the reviews and discussions referred to above, we recommended to the board (and the board
subsequently approved the recommendation) that the audited fi nancial statements be included in the company’s
annual report on Form 10-K for the year ended December 31, 2007, for fi ling with the Securities and Exchange Com-
mission. We have also appointed the company’s independent auditors, subject to shareholder ratifi cation, for 2008.
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Audit Committee
J. Michael Cook, Chair
Martin S. Feldstein, Ph.D.
Franklyn G. Prendergast, M.D., Ph.D.
Kathi P. Seifert
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Services Performed by the Independent Auditor
The audit committee preapproves all services performed by the independent auditor, in part to assess whether the pro-
vision of such services might impair the auditor’s independence. The committee’s policy and procedures are as follows:
• The committee approves the annual audit services engagement and, if necessary, any changes in terms,
conditions, and fees resulting from changes in audit scope, company structure, or other matters. The committee
may also preapprove other audit services, which are those services that only the independent auditor reasonably
can provide. Since 2004, audit services have included internal controls attestation work under Section 404 of the
Sarbanes-Oxley Act.
• Audit-related services are assurance and related services that are reasonably related to the performance of the
audit, and that are traditionally performed by the independent auditor. The committee believes that the provision
of these services does not impair the independence of the auditor.
• Tax services. The committee believes that, in appropriate cases, the independent auditor can provide tax
compliance services, tax planning, and tax advice without impairing the auditor’s independence.
• The committee may approve other services to be provided by the independent auditor if (i) the services are
permissible under SEC and Public Company Accounting Oversight Board rules, (ii) the committee believes the
provision of the services would not impair the independence of the auditor, and (iii) management believes that
the auditor is the best choice to provide the services.
• Process. At the beginning of each audit year, management requests prior committee approval of the annual
audit, statutory audits, and quarterly reviews for the upcoming audit year as well as any other engagements
known at that time. Management will also present at that time an estimate of all fees for the upcoming audit
year. As specifi c engagements are identifi ed thereafter, they are brought forward to the committee for approval.
To the extent approvals are required between regularly scheduled committee meetings, preapproval authority is
delegated to the committee chair.
For each engagement, management provides the committee with information about the services and fees suf-
fi ciently detailed to allow the committee to make an informed judgment about the nature and scope of the services
and the potential for the services to impair the independence of the auditor.
After the end of the audit year, management provides the committee with a summary of the actual fees in-
curred for the completed audit year.
Independent Auditor Fees
The following table shows the fees incurred for services rendered on a worldwide basis by Ernst & Young LLP, the
company’s independent auditor, in 2007 and 2006. All such services were preapproved by the committee in accor-
dance with the preapproval policy.
Audit Fees
• Annual audit of consolidated and subsidiary fi nancial statements, including Sarbanes-Oxley 404 attestation
• Reviews of quarterly fi nancial statements
• Other services normally provided by the auditor in connection with statutory and regulatory fi lings
Audit-Related Fees
• Assurance and related services reasonably related to the performance of the audit or reviews of the fi nancial statements
—2007 and 2006: primarily related to employee benefi t plan and other ancillary audits, and due diligence services on
possible acquisition in 2007
Tax Fees
• 2007 and 2006: primarily related to compliance services outside the U.S.
All Other Fees
• 2007 and 2006: primarily related to compliance services outside the U.S.
Total
2007
(millions)
2006
(millions)
$7.0
$5.8
$0.4
$0.4
$1.4
$1.5
$0.1
$0.1
$8.9
$7.8
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Compensation Committee Matters
Scope of Authority
The compensation committee oversees the company’s global compensation philosophy and establishes the com-
pensation of executive offi cers. The committee also acts as the oversight committee with respect to the company’s
deferred compensation plans, management stock plans, and bonus plans covering executives. In overseeing those
plans, the committee may delegate authority to company offi cers for day-to-day plan administration and interpre-
tation, including selecting participants, determining award levels within plan parameters, and approving award
documents. However, the committee may not delegate any authority for matters affecting the executive offi cers.
The Committee’s Processes and Procedures
The committee’s primary processes for establishing and overseeing executive compensation can be found in the
Compensation Discussion and Analysis section under “The Committee’s Processes and Analyses” on pages 81–82.
Additional processes and procedures include:
• Meetings. The committee meets several times each year (six times in 2007). Committee agendas are established
in consultation with the committee chair and the committee’s independent compensation consultant. The
committee meets in executive session after each meeting.
• Role of Independent Consultant. The committee has retained Frederic W. Cook and his fi rm, Frederic W. Cook &
Co., as its independent compensation consultant to assist the committee in evaluating executive compensation
programs and in setting executive offi cers’ compensation. Mr. Cook reports directly to the committee, and
neither he nor his fi rm is permitted to perform any services for management. The consultant’s duties include
the following:
—Review committee agendas and supporting materials in advance of each meeting and raise questions with
the company’s global compensation group and the committee chair as appropriate
—Review the company’s total compensation philosophy, peer group, and target competitive positioning for
reasonableness and appropriateness
—Review the company’s total executive compensation program and advise the committee of plans or practices
that might be changed to better refl ect evolving best practices
—Provide independent analyses and recommendations to the committee on the CEO’s pay
—Review draft Compensation Discussion and Analysis report and related tables for proxy statement
—Proactively advise committee on best practices ideas for board governance of executive compensation
—Undertake special projects at the request of the committee chair.
The consultant interacts directly with members of Lilly management only on matters under the committee’s
oversight and with the knowledge and permission of the committee chairperson.
• Role of Executive Offi cers and Management. With the oversight of the CEO, chief operating offi cer, and the senior
vice president of human resources, the company’s global compensation group formulates recommendations on
matters of compensation philosophy, plan design, and the specifi c compensation recommendations for executive
offi cers (other than the CEO as noted below). The CEO gives the committee a performance assessment and
compensation recommendation for each of the other named executive offi cers. Those recommendations are
then considered by the committee with the assistance of its compensation consultant. The CEO, the senior vice
president of human resources, and, less frequently, the COO attend committee meetings but are not present for
the executive sessions or for any discussion of their own compensation. (Only nonemployee directors and the
committee’s consultant attend executive sessions.)
The CEO does not participate in the formulation or discussion of his pay recommendations and has no
prior knowledge of the recommendations that the consultant makes to the committee.
Compensation Committee Interlocks and Insider Participation
None of the compensation committee members:
• has ever been an offi cer or employee of the company
• is or was a participant in a related-person transaction in 2007 (see page 72 for a description of our policy on
related-person transactions)
• is an executive offi cer of another entity, at which one of our executive offi cers serves on the board of directors.
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Executive Compensation
Compensation Discussion and Analysis
2007 Summary
Executive compensation for 2007 aligned well with the objectives of our compensation philosophy and with our
performance, driven by these factors:
• Strong operating results yield strong incentive compensation payouts. In 2007, Lilly performed in the top tier of its
peer group in sales growth and adjusted earnings per share growth; this strong top- and bottom-line growth led
to cash and equity incentive compensation payouts substantially above target.
• Equity design changes improve cost-effectiveness. We lowered the overall cost of our equity program in
2007—while maintaining its competitiveness and motivational impact—by eliminating stock options in favor of
shareholder value awards and by lowering total equity grant values for most positions.
• A balanced program fosters employee achievement, retention, and engagement. We delivered a balance of salary,
performance-based cash and equity incentives, and a strong employee benefi t program. Together, these
elements reinforced pay-for-performance incentives and encouraged employee retention and engagement.
For more detail, please see the remainder of this Compensation Discussion and Analysis section and the com-
pensation tables.
Executive Compensation Philosophy
Our success depends on our ability to discover, develop, and market a stream of innovative medicines that ad-
dress important medical needs. In addition, we must continually improve productivity in all that we do. To achieve
these goals, we seek to attract, engage, and retain highly talented individuals who are committed to the com-
pany’s core values of excellence, integrity, and respect for people. Our compensation and benefi t programs are
based on these objectives:
• Compensation should refl ect individual and company performance. We link all employees’ pay to individual and
company performance.
—As employees assume greater responsibilities, more of their pay is linked to company performance and
shareholder returns.
—We seek to deliver top-tier compensation given top-tier individual and company performance, but lower-tier
compensation where individual performance falls short of expectations and/or company performance lags
the industry.
—We design our programs to be simple and clear, so that employees can easily understand how their efforts
affect their pay.
—We balance the objectives of pay-for-performance and employee retention. Even during downturns in
company performance, the programs should continue to motivate and engage successful, high-achieving
employees.
• Compensation should foster a long-term focus. A long-term focus is critical to success in our industry. As
employees progress to higher levels of the organization, a greater portion of compensation is tied to our longer-
term performance.
• Compensation should be based on the level of job responsibility. We seek internal pay relativity, meaning that pay
differences among jobs should be commensurate with differences in the levels of responsibility and impact of
the jobs.
• Compensation should refl ect the marketplace for talent. We aim to remain competitive with the pay of other
premier employers with which we compete for talent.
• Compensation and benefi t programs should attract employees who are interested in a career at Lilly. Our employee
benefi t programs provide a competitive advantage by helping us attract and retain highly talented employees
who are looking for the opportunity to build careers.
• Compensation should be effi cient. To deliver superior long-term shareholder returns, we must deliver value to
employees in a cost-effective manner.
• Compensation and benefi t programs should be egalitarian. While compensation will always refl ect differences in
job responsibilities, geographies, and marketplace considerations, the overall structure of compensation and
benefi t programs should be broadly similar across the organization.
The Committee’s Processes and Analyses
The compensation committee uses several tools to help it structure compensation programs that meet company
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objectives. Among those are:
• Assessment of Company Performance. The committee uses company performance measures in two ways:
—In establishing total compensation ranges, the committee compares the performance of Lilly and its peer
group with respect to sales, earnings per share, return on assets, return on equity, and total shareholder
return. The committee uses this data as a reference point rather than applying a formula.
—The committee establishes specifi c company performance measures that determine payouts under the
company’s cash and equity formula-based incentive programs.
• Assessment of Individual Performance. Individual performance has a strong impact on compensation. The
independent directors, under the direction of the presiding director, meet with the CEO in executive session at
the beginning of the year to agree upon the CEO’s performance objectives for the year. At the end of the year, the
independent directors again meet in executive session to review the performance of the CEO based on his or her
achievement of the agreed-upon objectives, contribution to the company’s performance, and other leadership
accomplishments. This evaluation is shared with the CEO by the presiding director and is provided to the
compensation committee for its consideration in setting the CEO’s compensation.
For the other named executive offi cers, the committee receives a performance assessment and
compensation recommendation from the CEO and also exercises its judgment based on the board’s
interactions with the executive offi cer. As with the CEO, the executive’s performance evaluation is based on
the executive’s achievement of objectives established between the executive and his or her supervisor, the
executive’s contribution to the company’s performance, and other leadership accomplishments.
• Peer Group Analysis. The committee compares the company’s programs with a peer group of global
pharmaceutical companies. Pharmaceutical companies’ needs for scientifi c and sales/marketing talent are
unique to the industry and as such, Lilly must compete with these companies for talent: Abbott Laboratories;
Amgen; Bristol-Myers Squibb Company; GlaxoSmithKline; Johnson & Johnson; Merck & Co.; Pfi zer, Inc.;
Schering-Plough Corporation; and Wyeth Laboratories. The committee uses the peer group data in two ways:
—Overall competitiveness. The committee uses aggregated data as a reference point to ensure that the
executive compensation program as a whole is competitive, meaning within the broad middle range of
comparative pay of the peer group companies when the company achieves the targeted performance levels.
The committee does not target a specifi c position within the range.
—Individual competitiveness. The committee compares the overall pay of individual executives, if the jobs are
suffi ciently similar to make the comparison meaningful. The individual’s pay is driven primarily by individual
and company performance and internal relativity rather than the peer group data; the peer group data is used
as a “market check” to ensure that individual pay remains within the broad middle range of peer group pay.
Again, the committee does not target a specifi c position within the range.
• CEO Compensation. To provide further assurance of independence, the compensation recommendation for
the CEO is developed by the independent consultant (Frederic W. Cook and his fi rm, Frederic W. Cook & Co.)
without the input or knowledge of the CEO and with limited support from company staff. The Cook fi rm prepares
analyses showing median CEO compensation among the peer group in terms of base salary, target annual
incentive award, most recent equity grant value, and resulting total direct compensation. Mr. Cook develops a
range of recommendations for any change in the CEO’s base salary, annual incentive target, and equity grant
value and mix. Mr. Cook’s recommendations for target CEO pay take into account the peer competitive pay
analysis and, importantly, the position of the CEO in relation to other senior company executives and proposed
pay actions for all key employees of the company. The range allows for the committee to exercise its discretion
based on the CEO’s individual performance. The CEO has no prior knowledge of the recommendations and takes
no part in the recommendations, committee discussions, or decisions.
Executive Compensation for 2007
Overview—Establishment of Overall Pay
In making its pay decisions for 2007, the committee reviewed 2006 company performance data and peer group data
as discussed above, and also considered expected competitive trends in executive pay. That review showed:
• Company performance. In 2006, Lilly performed in the upper tier of the peer group in adjusted earnings per share
growth, return on assets, and return on equity; in the middle tier in sales growth; and in the lower tier in total
shareholder return.
• Pay relative to peer group. For the one- and three-year periods ended 2006, Lilly’s total pay to executive offi cers
was in the broad middle range.
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The committee determined the following:
• Program elements. The 2007 program consisted of base salary, a cash incentive bonus award, and two forms
of performance-based equity grants—performance awards and shareholder value awards (SVAs). Executives
also received the company employee benefi t package. This program balances the mix of cash and equity
compensation, the mix of current and longer-term compensation, and the security of foundational benefi ts in a
way that furthers the compensation objectives discussed above.
• Pay ranges and mix of pay elements. To manage the overall costs of the program while remaining competitive
with expected peer group compensation, 2007 target pay ranges were reduced in the aggregate across the
management and executive ranks, and the mix of pay was shifted. This was accomplished by:
—eliminating stock options in favor of SVAs, which provide greater retention and motivation value to employees
at a lower cost to shareholders
—reducing the target values for equity awards for most positions by up to 15 percent
—increasing base salaries modestly, consistent with the corporate merit budget
—maintaining cash bonus targets at 2006 levels.
The committee believes that these changes resulted in a more cost-effective program that:
—reduces overall costs to the company
—strengthens the incentives for retention and employee engagement by delivering a competitive cash
component and the new SVA program
—maintains a strong link to company performance and shareholder returns through a balanced equity
incentive program
—maintains appropriate internal pay relativity
—provides opportunity for total pay within the broad middle range of expected peer group pay given company
performance comparable to that of our peers.
Base Salary
In setting base salaries for 2007, the committee considered the following:
• The corporate “merit budget,” the company’s overall budget for base salary increases. The corporate merit
budget was established based on company performance for 2006, planned performance for 2007, and a
reference to general external merit trends. The objective of the merit budget is to allow salary increases
to retain, motivate, and reward successful performers while maintaining affordability within the company’s
business plan. Individual pay increases can be more or less than the budget amount depending on individual
performance, but aggregate increases must stay within the budget. The aggregate increases for all executive
offi cers were within the corporate merit budget.
• Individual performance. As described above under “The Committee’s Processes and Analyses,” base salary
increases were driven largely by individual performance assessments.
—The independent directors assessed Mr. Taurel’s 2006 performance. They considered the company’s and
Mr. Taurel’s accomplishment of objectives that had been established at the beginning of the year and its
own subjective assessment of his performance. They noted that under Mr. Taurel’s leadership, in 2006 the
company exceeded its earnings targets through sales growth and productivity improvements, drove progress
in refi ning and implementing the long-term strategy, met aggressive Six Sigma goals, strengthened its
diversity programs, and enhanced its brand image and reputation. In recognition of his continued strong
leadership in 2006, the committee increased Mr. Taurel’s annual salary by 4 percent, which was within the
range recommended by the committee’s consultant.
—The committee reviewed similar considerations for each of the other named executives. In addition, with
regard to Dr. Lechleiter’s performance, the committee considered his leadership in increasing employee
productivity and implementation of strategic initiatives. The committee increased Dr. Lechleiter’s annual
salary by 4 percent.
—With regard to Dr. Paul, the committee gave particular weight to his leadership of the company’s research
and development efforts, noting that Lilly Research Laboratories improved productivity in several phases of
discovery and development, increased the percentage of pipeline molecules currently in clinical trials, and
forged stronger links between research and the sales and marketing organizations. The committee increased
Dr. Paul’s annual salary by 5 percent.
—In establishing Mr. Armitage’s annual salary (a 5 percent increase), the committee noted his leadership
in implementing successful litigation strategies, leading the company’s efforts to infl uence the legal and
regulatory environment to support innovation, and improving productivity within the law division.
—Mr. Rice’s annual salary was increased 6 percent in recognition of strong internal controls and an improved
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fi nancial planning process, as well as his strong leadership of, and development of talent within, the fi nancial
component and his outstanding contributions to the management of the company.
• Internal relativity, meaning the relative pay differences for different job levels.
• Peer group data specifi c to certain positions in which the jobs were viewed as comparable in content and
importance to the company. We used the peer group data not to target a specifi c position in range, but instead
as a market check for reasonableness and competitiveness. The salaries as determined by the other factors
were within the broad middle range of expected competitive pay and, therefore, no further adjustments were
necessary for competitiveness.
Cash Incentive Bonuses
The company’s annual cash bonus programs align employees’ goals with the company’s sales and earnings growth
objectives for the current year. Cash incentive bonuses for all management employees worldwide, as well as most
nonmanagement employees in the U.S., are determined under the Eli Lilly and Company Bonus Plan. Under the
plan, the company sets target bonus amounts (a percentage of base salary) for all participants at the beginning of
each year. Bonus payouts range from zero to 200 percent of target depending on the company’s fi nancial results
relative to predetermined performance measures. At the end of the performance period, the committee has dis-
cretion to adjust an award payout downward, but not upward, from the amount yielded by the formula.
The committee considered the following when establishing the 2007 awards:
• Target bonus sizes. Bonus targets (expressed as a percentage of base salary) were based on job responsibilities,
internal relativity, and peer group data. Consistent with our compensation objectives, as executives assume
greater responsibilities, more of their pay is linked to company performance. For 2007, the committee
maintained the same bonus targets as in 2006. The committee determined that these targets appropriately
refl ected internal relativity. In addition, the peer group data suggested that the 2006 targets would maintain cash
compensation within the broad middle range of expected competitive pay given median peer performance, so no
adjustments were necessary. The 2007 targets for the named executives were as follows:
—Mr. Taurel – 125 percent
—Dr. Lechleiter – 100 percent
—Dr. Paul – 85 percent
—Mr. Armitage – 75 percent
—Mr. Rice – 75 percent.
• Company performance measures. The committee established 2007 company performance measures with a 25
percent weighting on sales growth and a 75 percent weighting on growth in adjusted EPS (reported earnings per
share adjusted as described below under “Adjustments for Certain Items”). This mix of performance measures
focuses employees appropriately on improving both top-line sales and bottom-line earnings, with special
emphasis on earnings in order to tie rewards directly to productivity improvements. The measures are also
effective motivators because they are easy for employees to track and understand.
In establishing the 2007 target growth rates, the committee considered the expected 2007 performance
of our peer group, based on published investment analyst estimates. The target growth rates of 5 percent
for sales and 8 percent for adjusted EPS represented approximately the median expected growth rates for
our peer group. These targets are consistent with our compensation objectives because they result in above-
target payouts if Lilly outperforms the peer group and below-target payouts if Lilly performance lags the peer
group. Payouts were determined by this formula:
(0.25 x sales multiple) + (0.75 x adjusted EPS multiple) = bonus multiple
Bonus multiple X target bonus X base salary earnings = payout
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2007 sales and adjusted EPS multiples are illustrated by these charts:
(cid:39)(cid:37)(cid:37)(cid:44)(cid:21)(cid:72)(cid:86)(cid:97)(cid:90)(cid:104)(cid:21)(cid:66)(cid:106)(cid:97)(cid:105)(cid:94)(cid:101)(cid:97)(cid:90)
(cid:90)
(cid:97)
(cid:101)
(cid:94)
(cid:105)
(cid:97)
(cid:106)
(cid:66)
(cid:104)
(cid:90)
(cid:97)
(cid:86)
(cid:72)
(cid:21)
(cid:39)(cid:35)(cid:42)
(cid:39)(cid:35)(cid:37)
(cid:38)(cid:35)(cid:42)
(cid:38)(cid:35)(cid:37)
(cid:37)(cid:35)(cid:42)
(cid:37)
(cid:38)(cid:36)(cid:46)
(cid:39)
(cid:38)(cid:36)(cid:43)
(cid:38)(cid:36)(cid:44)
(cid:39)(cid:36)(cid:42)
(cid:39)(cid:36)(cid:44)
(cid:39)(cid:36)(cid:40)
(cid:39)(cid:36)(cid:46)
(cid:40)
(cid:21) (cid:34)(cid:38)(cid:26)(cid:21)
(cid:38)(cid:26)(cid:21)
(cid:40)(cid:26)(cid:21)
(cid:42)(cid:26)(cid:21)
(cid:44)(cid:26)(cid:21)
(cid:46)(cid:26)(cid:21)
(cid:38)(cid:38)(cid:26)(cid:21)
(cid:38)(cid:40)(cid:26)(cid:21)
(cid:38)(cid:42)(cid:26)
2007 pro forma sales growth of 13.6 percent resulted in a sales multiple of 1.861.
(cid:72)(cid:86)(cid:97)(cid:90)(cid:104)(cid:21)(cid:60)(cid:103)(cid:100)(cid:108)(cid:105)(cid:93)
(cid:39)(cid:37)(cid:37)(cid:44)(cid:21)(cid:54)(cid:89)(cid:95)(cid:106)(cid:104)(cid:105)(cid:90)(cid:89)(cid:21)(cid:58)(cid:69)(cid:72)(cid:21)(cid:66)(cid:106)(cid:97)(cid:105)(cid:94)(cid:101)(cid:97)(cid:90)
(cid:21)
(cid:90)
(cid:97)
(cid:101)
(cid:94)
(cid:105)
(cid:97)
(cid:106)
(cid:66)
(cid:72)
(cid:69)
(cid:58)
(cid:89)
(cid:90)
(cid:105)
(cid:104)
(cid:106)
(cid:89)
(cid:54)
(cid:95)
(cid:21)
(cid:39)(cid:35)(cid:42)
(cid:39)(cid:35)(cid:37)
(cid:38)(cid:35)(cid:42)
(cid:38)(cid:35)(cid:37)
(cid:38)(cid:36)(cid:42)
(cid:37)(cid:35)(cid:42)
(cid:37)
(cid:21)
(cid:39)(cid:26)(cid:21)
(cid:39)(cid:36)(cid:42)
(cid:39)(cid:36)(cid:44)
(cid:39)(cid:36)(cid:46)
(cid:40)
(cid:38)(cid:36)(cid:46)
(cid:38)(cid:36)(cid:44)
(cid:39)(cid:36)(cid:40)
(cid:39)
(cid:41)(cid:26)(cid:21)
(cid:43)(cid:26)(cid:21)
(cid:45)(cid:26)(cid:21)
(cid:38)(cid:37)(cid:26)(cid:21)
(cid:38)(cid:39)(cid:26)(cid:21)
(cid:38)(cid:41)(cid:26)(cid:21)
(cid:38)(cid:43)(cid:26)(cid:21)
(cid:38)(cid:45)(cid:26)
(cid:54)(cid:89)(cid:95)(cid:106)(cid:104)(cid:105)(cid:90)(cid:89)(cid:21)(cid:58)(cid:69)(cid:72)(cid:21)(cid:60)(cid:103)(cid:100)(cid:108)(cid:105)(cid:93)
2007 pro forma adjusted EPS growth of 16.8 percent resulted in an adjusted EPS multiple of 1.883.
Together, the sales multiple and the adjusted EPS multiple yielded a bonus multiple of 1.88:
(0.25 x 1.861) + (0.75 x 1.883) = 1.88 bonus multiple
See page 87 for a reconciliation of 2007 reported and pro forma sales and reported and pro forma adjusted EPS.
Equity Incentives—Total Equity Program
In 2007, we employed two forms of equity incentives granted under the 2002 Lilly Stock Plan: performance awards
and shareholder value awards. These incentives ensure that our leaders are properly focused on long-term share-
holder value.
• Target grant values. For 2007, the committee reduced aggregate grant values for management and executives
in order to manage overall compensation costs. The committee did not “make up” for the equity reductions by
signifi cantly increasing other elements of compensation. The specifi c reductions at different job levels were
determined by internal relativity. Consistent with the company’s compensation objectives, individuals at higher
levels received a greater proportion of total pay in the form of equity. The committee determined that a 50/50
split for executives between performance awards and shareholder value awards appropriately balances
the shorter- and longer-term incentives of the two programs. This is consistent with the 2006 grants,
which were split 50/50 between performance awards and stock options.
Target values for 2007 equity grants for the named executives were as follows:
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Name
Mr. Taurel
Dr. Lechleiter
Dr. Paul
Mr. Armitage
Mr. Rice
Performance
Awards
Shareholder Value
Awards
$3,060,000
$1,989,000
$1,200,000
$855,000
$855,000
$3,060,000
$1,989,000
$1,200,000
$855,000
$855,000
8585
Two named executive offi cers did not receive reductions in their target equity values. Dr. Paul’s 2007 value
remained the same as in 2006 to preserve competitiveness within peer company pay and to recognize the strategic
importance of the chief scientifi c offi cer role. Mr. Rice’s 2007 value increased due to his promotion in May 2006.
Equity Incentives—Performance Awards
Performance awards provide employees with shares of Lilly stock if certain company performance goals are
achieved, aligning employees with shareholder interests and providing an ownership stake in the company. The
awards are structured as a schedule of shares of Lilly stock based on the company’s achievement of specifi c ad-
justed earnings per share (adjusted EPS) levels over specifi ed time periods of one or more years. Possible payouts
range from zero to 200 percent of the target amount, depending on adjusted EPS growth over the period. No divi-
dends are paid on the awards during the performance period. At the end of the performance period, the committee
has discretion to adjust an award payout downward, but not upward, from the amount yielded by the formula. For
the 2007 grants, the committee took into consideration the following:
• Target grant values. As described above, the committee reduced target grant values for most job levels and
established a 50/50 split for executives between performance awards and SVAs.
• Company performance measure. The committee established the performance measure as adjusted EPS growth
(reported EPS adjusted as described below under “Adjustments for Certain Items”) over a one-year period, with
a one-year holding period, thus creating a two-year award. The committee believes adjusted EPS growth is an
effective motivator because it is closely linked to shareholder value, is broadly communicated to the public,
and is easily understood by employees. In setting the target growth percentage of 8 percent, the committee
considered the expected earnings performance of companies in our peer group over a one-year period, based on
published investment analyst estimates. Eight percent represented approximately the median expected growth
for our peer group; accordingly, consistent with our compensation objectives, Lilly performance exceeding the
peer group median would result in above-target payouts while Lilly performance lagging the peer group median
would result in below-target payouts. Payouts were determined according to this schedule:
Adjusted 2007 EPS Growth
Up to 2.99% 3.00–4.99% 5.00–6.99% 7.00–8.99% 9.00–10.99% 11.00–12.99% 13.00–15.99% 16.00% +
Percent of Target
0
50%
75%
100%
125%
150%
175%
200%
Pro forma adjusted EPS growth of 16.8 percent resulted in a 2007 performance award payout at 200 percent of
target. See page 87 for a reconciliation of 2007 reported and pro forma adjusted EPS.
Equity Incentives—Shareholder Value Awards
Beginning in 2007, the company implemented a new equity program, the shareholder value award (SVA), which re-
placed our stock option program. The SVA pays out shares of Lilly stock based on the performance of the compa-
ny’s stock over a three-year period. No dividends are paid on the awards during the performance period. Payouts
range from zero to 140 percent of the target amount, depending on stock price performance over the period. The
SVA program delivers equity compensation that is strongly linked to longer-term shareholder returns. It is more
cost-effective than the stock option program it replaces because the SVA program delivers, at a lower cost to the
company, an equity incentive that is equally or more effective in aligning employee interests with long-term share-
holder return. For the 2007 grants, the committee considered the following:
• Target grant size. As described above, the committee reduced target grant sizes for most job levels and
established a 50/50 split between performance awards and SVAs.
• Company performance measure. The SVA is designed to pay above target if Lilly’s stock price outperforms
an expected compounded annual rate of return for large-cap companies and below target if Lilly stock
underperforms that rate of return. The expected rate of return used in this calculation was determined
considering total return that a reasonable investor would consider appropriate for investing in the stock of a
large-cap U.S. company, based on input from external money managers, less Lilly’s current dividend yield.
Executive offi cers receive no payout if the stock price (less three years of dividends at the current rate) does not
grow over the three-year performance period—in other words, if total shareholder return for the three-year
period is zero or negative.
The starting price for the 2007 SVAs was $54.01 per share, representing the average of the closing prices of
Lilly stock for all trading days in November and December 2006. The ending price to determine payouts will be
the average of the closing prices of Lilly stock for all trading days in November and December 2009.
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Payouts will be determined by this grid:
Ending Stock Price
Up to $48.72
$48.72–$53.85 $53.86–$58.99 $59.00–$62.99 $63.00–$66.99 $67.00–$70.99
$71.00 +
Percent of Target
0
40%
60%
80%
100%
120%
140%
Adjustments for Certain Items
Consistent with past practice, the committee adjusted the results on which 2007 bonuses and performance awards
were determined to eliminate the effect of certain unusual income or expense items. The adjustments are intended to:
• align award payments with the underlying growth of the core business
• avoid volatile, artifi cial infl ation or defl ation of awards due to the unusual items either in the award year or the
previous (comparator) year
• eliminate certain counterproductive short-term incentives—for example, incentives to refrain from acquiring
new technologies or to defer disposing of underutilized assets or settling legacy litigation in order to protect
current bonus payments.
To assure the integrity of the adjustments, the committee establishes adjustment guidelines at the beginning of the
year. These guidelines are consistent with the company guidelines for reporting adjusted earnings to the investment
community, which are reviewed by the audit committee of the board. The adjustments apply equally to income and
expense items and must exceed a materiality threshold. The committee reviews all adjustments and retains “downward
discretion”—i.e., discretion to reduce compensation below the amounts that are yielded by the adjustment guidelines.
For the 2007 awards calculation, the committee adjusted EPS to eliminate the effect in 2007 of accounting
charges for the acquisition of in-process research and development (IPR&D), and in both 2006 and 2007 of major
product liability charges, major asset impairments, restructuring, and other special charges. In addition, to elimi-
nate the distorting effect of the acquisition of ICOS Corporation (which was completed in January 2007) on year-
over-year growth rates, the committee adjusted sales and EPS for both 2006 and 2007 on a pro forma basis as if
the acquisition had been completed at the beginning of 2006.
The adjustments were intended to align award payments more closely to underlying business growth trends
and eliminate volatile swings (up or down) caused by the unusual items. This is demonstrated by the 2006 and 2007
adjustments:
(cid:69)(cid:90)(cid:103)(cid:88)(cid:90)(cid:99)(cid:105)(cid:21)(cid:60)(cid:103)(cid:100)(cid:108)(cid:105)(cid:93)(cid:21)(cid:107)(cid:104)(cid:35)(cid:21)(cid:69)(cid:103)(cid:94)(cid:100)(cid:103)(cid:21)(cid:78)(cid:90)(cid:86)(cid:103)
(cid:73)(cid:87)(cid:98)(cid:91)(cid:105)(cid:22)(cid:61)(cid:104)(cid:101)(cid:109)(cid:106)(cid:94)
(cid:59)(cid:70)(cid:73)(cid:22)(cid:61)(cid:104)(cid:101)(cid:109)(cid:106)(cid:94)
(cid:39)(cid:37)(cid:37)(cid:43)(cid:21)(cid:71)(cid:90)(cid:101)(cid:100)(cid:103)(cid:105)(cid:90)(cid:89)(cid:21)
(cid:39)(cid:37)(cid:37)(cid:43)(cid:21)(cid:54)(cid:89)(cid:95)(cid:106)(cid:104)(cid:105)(cid:90)(cid:89)(cid:21)
(cid:39)(cid:37)(cid:37)(cid:44)(cid:21)(cid:71)(cid:90)(cid:101)(cid:100)(cid:103)(cid:105)(cid:90)(cid:89)(cid:21) (cid:39)(cid:37)(cid:37)(cid:44)(cid:21)(cid:69)(cid:103)(cid:100)(cid:21)(cid:59)(cid:100)(cid:103)(cid:98)(cid:86)(cid:21)(cid:54)(cid:89)(cid:95)(cid:106)(cid:104)(cid:105)(cid:90)(cid:89)
(cid:41)(cid:37)
(cid:40)(cid:42)
(cid:40)(cid:37)
(cid:39)(cid:42)
(cid:39)(cid:37)
(cid:38)(cid:42)
(cid:38)(cid:37)
(cid:42)
(cid:37)
(cid:21)
Reconciliations of the adjustments to our reported sales and earnings per share are below. The shaded num-
bers were used for calculating growth percentages for the compensation programs.
Sales as reported ($ millions)
pro forma ICOS adjustment
Sales—pro forma adjusted
EPS as reported
Eliminate IPR&D charges for acquisitions and in-licensing
transactions
Eliminate asset impairments, restructuring and other special
charges (including product liability charges)
Eliminate cumulative effect of change in accounting principle
EPS—adjusted
pro forma ICOS adjustment
EPS—pro forma adjusted
2007
2006
% Growth
2007 vs. 2006
2005
% Growth
2006 vs. 2005
$18,633.5
$15,691.0
19%
$14,645.3
7%
$72.7
$755.2
$18,706.2
$16,446.2
$2.71
$2.45
14%
11%
$.63
$.21
—
$3.55
$(.01)
$3.54
—
$.73
—
$3.18
$(.15)
$3.03
17%
N/A
N/A
$1.81
—
$1.04
$.02
$2.87
N/A
N/A
N/A
35%
11%
N/A
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Equity Incentive Grant Mechanics and Timing
The committee approves target grant values for equity incentives prior to the grant date. On the grant date, those
values are converted to shares based on:
• the closing price of Lilly stock on the grant date
• the same valuation methodology the company uses to determine the accounting expense of the grants under
Statement of Financial Accounting Standards (SFAS) 123R.
The committee’s procedure for timing of equity grants assures that grant timing is not being manipulated for
employee gain. The annual equity grant date for all eligible employees is in mid-February. This date is established
by the committee well in advance—typically at the committee’s October meeting. The mid-February grant date tim-
ing is driven by these considerations:
• It coincides with the company’s calendar-year-based performance management cycle, allowing supervisors to
deliver the equity awards close in time to performance appraisals, which increases the impact of the awards by
strengthening the link between pay and performance.
• It follows the annual earnings release by approximately two weeks, so that the stock price at that time can
reasonably be expected to fairly represent the market’s collective view of our then-current results and prospects.
Grants to new hires and other off-cycle grants are effective on the fi rst trading day of the following month.
Employee and Post-Employment Benefi ts
The company offers core employee benefi ts coverage in order to:
• provide our global workforce with a reasonable level of fi nancial support in the event of illness or injury
• enhance productivity and job satisfaction through programs that focus on work/life balance.
The benefi ts available are the same for all U.S. employees and include medical and dental coverage, disability
insurance, and life insurance.
In addition, the Lilly 401(k) Plan and the Lilly Retirement Plan provide a reasonable level of retirement income
refl ecting employees’ careers with the company. U.S. employees are eligible to participate in these plans. To the
extent that any employee’s retirement benefi t exceeds IRS limits for amounts that can be paid through a qualifi ed
plan, Lilly also offers a nonqualifi ed retirement plan and a nonqualifi ed savings plan. These plans provide only the
difference between the calculated benefi ts and the IRS limits, and the formula is the same for all U.S. employees.
The cost of both employee and post-employment benefi ts is partially borne by the employee, including each
executive offi cer.
Perquisites
The company does not provide signifi cant perquisites to executive offi cers, except that the company aircraft is
made available for the personal use of Mr. Taurel and Dr. Lechleiter, where the committee believes the security
and effi ciency benefi ts to the company clearly outweigh the expense. The company aircraft is also made available
to other executive offi cers for travel to outside board meetings. In addition, depending on seat availability, family
members of executive offi cers may travel on the company aircraft to accompany executives who are traveling on
business. There is no incremental cost to the company for these trips.
Mr. Taurel’s primary use of the corporate aircraft for personal fl ights in 2007 was to attend outside board
meetings for the two public companies at which he serves as an independent director. The committee believes that
Mr. Taurel’s service on these boards, and his ability to conduct Lilly business while traveling to board meetings,
provides clear benefi ts to the company. As described on pages 100–101, Mr. Taurel has entered into a time-share
arrangement for the corporate aircraft under which he pays the company a lease fee for personal use, other than
for attending outside board meetings. This amount offsets part of the company’s incremental cost of providing the
aircraft. Dr. Lechleiter did not use the corporate aircraft for personal fl ights during 2007.
Deferred Compensation Program
Executives may defer receipt of part or all of their cash compensation under the company’s deferred compensation
program. The program allows executives to save for retirement in a tax-effective way at minimal cost to the company.
Under this unfunded program, amounts deferred by the executive are credited at an interest rate of 120 percent of the
applicable federal long-term rate, as described in more detail following the Nonqualifi ed Deferred Compensation in
2007 table on page 97.
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Severance Benefi ts
Except in the case of a change in control of the company, the company is not obligated to pay severance to named
executive offi cers upon termination of their employment.
The company has adopted a change-in-control severance pay program for nearly all employees of the com-
pany, including the executive offi cers. The program is intended to preserve employee morale and productivity and
encourage retention in the face of the disruptive impact of an actual or rumored change in control of the company.
In addition, for executives, the program is intended to align executive and shareholder interests by enabling execu-
tives to consider corporate transactions that are in the best interests of the shareholders and other constituents
of the company without undue concern over whether the transactions may jeopardize the executives’ own employ-
ment. Because this program is guided by different objectives than the regular compensation program, decisions
made under this program do not affect the regular compensation program.
Although there are some differences in benefi t levels depending on the employee’s job level and seniority, the
basic elements of the program are comparable for all employees:
• Double trigger. Unlike “single trigger” plans that pay out immediately upon a change in control, the Lilly program
generally requires a “double trigger”—a change in control followed by an involuntary loss of employment within
two years thereafter. This is consistent with the purpose of the program, which is to provide employees with a
guaranteed level of fi nancial protection upon loss of employment. A partial exception is made for performance
awards, a portion of which would be paid out upon a change in control, based on time worked up to the change in
control and the target or forecasted payout level at the time of the change in control. The committee believes this
partial payment is appropriate because of the diffi culties in converting the Lilly EPS targets into an award based
on the surviving company’s EPS. Likewise, if Lilly is not the surviving entity, a portion of the shareholder value
awards are paid out, based on time worked up to the change in control and the merger price for Lilly stock.
• Covered terminations. Employees are eligible for payments if, within two years of the change in control, their
employment is terminated (i) without cause by the company or (ii) for good reason by the employee, each as
is defi ned in the program. See pages 98–100 for a more detailed discussion, including a discussion of what
constitutes a change in control.
• Two-year protections. Employees who suffer a covered termination receive up to two years of pay and benefi t
protection. The purpose of these provisions is to assure employees a reasonable period of protection of their
income and core employee benefi ts upon which they depend for fi nancial security.
—Severance payment. Eligible terminated employees would receive a severance payment ranging from six
months’ to two years’ base salary. Executives are all eligible for two years’ base salary plus cash bonus (with
bonus established as the higher of the then-current year’s target bonus or the last bonus paid prior to the
change in control).
—Benefi t continuation. Basic employee benefi ts such as health and life insurance would be continued for up
to two years following termination of employment. All executives, including named executive offi cers, are
entitled to two years’ benefi t continuation.
—Pension supplement. Under the portion of the program covering executives, a terminated employee would be
entitled to a supplement of two years of age credit and two years of service credit for purposes of calculating
eligibility and benefi t levels under the company’s defi ned benefi t pension plan.
• Accelerated vesting of equity awards. Any unvested equity awards at the time of termination of employment would
become vested.
• Excise tax. In some circumstances, the payments or other benefi ts received by the employee in connection with
a change in control may exceed certain limits established under Section 280G of the Internal Revenue Code.
The employee would then be subject to an excise tax on top of normal federal income tax. Because of the way
the excise tax is calculated, it can impose a large burden on some employees while similarly compensated
employees will not be subject to the tax. The costs of this excise tax—but not the regular income tax—would
be borne by the company. To avoid triggering the excise tax, payments that would otherwise be due under the
program that are up to 3 percent over the IRS limit will be cut back to the IRS limit.
Share Ownership and Retention Guidelines; Hedging Prohibition
Share ownership and retention guidelines help to foster a focus on long-term growth. The committee has adopted
a guideline requiring the CEO to own Lilly stock valued at least fi ve times his or her annual base salary, and other
executive offi cers to own at least three times their annual base salary. A phase-in of up to fi ve years is provided for
newly hired or promoted executive offi cers. Lilly executives have a long history of maintaining extensive holdings in
Lilly stock, and all executive offi cers already meet or exceed the guideline, or in the case of new executive offi cers,
are on track to meet or exceed the guideline within the phase-in period. Currently Mr. Taurel and Dr. Lechleiter
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hold shares valued at 35 and 10 times their respective annual salaries.
Executive offi cers are required to retain all shares received from the company equity programs, net of acqui-
sition costs and taxes, for at least one year. In addition, any executive offi cer who does not meet the stock owner-
ship guideline must retain all net shares until the requisite ownership level is achieved.
Employees are not permitted to hedge their economic exposures to the Lilly stock that they own through short
sales or derivative transactions.
Tax Deductibility Cap on Executive Compensation
U.S. federal income tax law prohibits the company from taking a tax deduction for certain compensation paid in
excess of $1,000,000 to certain executive offi cers. However, performance-based compensation is fully deductible
if the programs are approved by shareholders and meet other requirements. Our policy is to qualify our incentive
compensation programs for full corporate deductibility to the extent feasible and consistent with our overall com-
pensation objectives.
We have taken steps to qualify cash bonus compensation, performance awards, and SVAs for full deductibility
as “performance-based compensation.” The committee may make payments that are not fully deductible if, in its
judgment, such payments are necessary to achieve the company’s compensation objectives and to protect share-
holder interests. For 2007, the non-deductible compensation under this law was essentially equal to the portion
of Mr. Taurel’s and Dr. Lechleiter’s base salary that exceeded $1,000,000 as shown in the Summary Compen-
sation Table.
Executive Compensation Recovery Policy
Any incentive awards, including SVAs, are subject to forfeiture prior to payment for termination of employment or
disciplinary reasons. In addition, the committee has adopted an executive compensation recovery policy applicable
to executive offi cers. Under this policy, the company may recover incentive compensation (cash or equity) that
was based on achievement of fi nancial results that were subsequently the subject of a restatement if an executive
offi cer engaged in intentional misconduct that caused or partially caused the need for the restatement and the ef-
fect of the wrongdoing was to increase the amount of bonus or incentive compensation. This policy covers income
related to cash bonuses and performance awards. SVAs are not covered due to the diffi culty in attributing stock
price movements to specifi c causes.
2008 Compensation Decisions—CEO Transition
Mr. Taurel will retire as CEO effective March 31, 2008 and as chairman of the board effective December 31, 2008.
Dr. Lechleiter has been elected CEO effective April 1, 2008. The committee has approved revised cash compensa-
tion for Mr. Taurel and Dr. Lechleiter in their new roles.
• Mr. Taurel. As chairman, Mr. Taurel will remain an employee of the company until his retirement on December
31, 2008. Effective April 1, 2008, his base salary will be reduced by half. Under the terms of the Eli Lilly and
Company Bonus Plan, his non-equity incentive award opportunity is calculated as a percentage of base salary
earnings, and therefore his incentive award for the period of April through December 2008 will also be reduced
by half. Thus, effective April 1, 2008, Mr. Taurel will receive the following annualized base salary and target non-
equity incentive plan compensation (both fi gures are shown as if they were paid for a full year, but will actually
be paid for only the nine months from April through December 2008):
—Annualized base salary—$864,250
—Annualized target non-equity incentive plan compensation—$1,209,950*
• Dr. Lechleiter. Effective April 1, 2008, Dr. Lechleiter will receive the following annualized base salary and target
non-equity incentive plan compensation (both fi gures are shown as if they were paid for a full year, but will
actually be paid for only the nine months from April through December 2008):
—Annualized base salary—$1,400,000
—Annualized target non-equity incentive plan compensation—$1,960,000*
* These amounts represent the target bonus under the Eli Lilly and Company Bonus Plan, assuming the
annualized base salary was paid for the entire calendar year. Actual bonuses paid for a given calendar
year will be calculated on actual base salary earnings for the year, and may vary from target depending on
company performance in 2008. See pages 84–85 for a description of the Bonus Plan.
Compensation Committee Report
The compensation committee (“we” or “the committee”) evaluates and establishes compensation for executive of-
fi cers and oversees the deferred compensation plan, the company’s management stock plans, and other manage-
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ment incentive, benefi t, and perquisite programs. Management has the primary responsibility for the company’s
fi nancial statements and reporting process, including the disclosure of executive compensation. With this in mind,
we have reviewed and discussed with management the Compensation Discussion and Analysis found on pages
81–90 of this proxy statement. The committee is satisfi ed that the Compensation Discussion and Analysis fairly and
completely represents the philosophy, intent, and actions of the committee with regard to executive compensa-
tion. We recommended to the board of directors that the Compensation Discussion and Analysis be included in this
proxy statement for fi ling with the Securities and Exchange Commission.
Compensation Committee
Karen N. Horn, Ph.D., Chair
George M.C. Fisher
J. Erik Fyrwald
Ellen R. Marram
Summary Compensation Table 1
Name and Principal
Position
Sidney Taurel
Chairman of the Board and
Chief Executive Offi cer
Year
2007
2006
Salary
($)
Stock Awards2
($)
Option Awards2
($)
Non-Equity
Incentive Plan
Compensation3
($)
Change in
Pension Value4
($)
All Other
Compensation5
($)
Total
Compensation
($)
$1,717,417
$1,650,333
$6,443,000
$5,400,000
$600,000
$3,805,333
$4,035,929
$2,764,308
0
$1,417,434
$215,044
$192,409
$13,011,390
$15,229,817
John C. Lechleiter, Ph.D.
President and Chief
Operating Offi cer
Steven M. Paul, M.D.
Executive Vice President,
Science and Technology
Robert A. Armitage
Senior Vice President and
General Counsel
Derica W. Rice
Senior Vice President and
Chief Financial Offi cer
2007
2006
$1,149,083
$1,112,000
$4,641,000
$3,510,000
$390,000
$3,967,976
$2,160,277
$1,490,080
$921,394
$1,156,247
$70,761
$68,790
$9,332,515
$11,305,093
2007
2006
2007
2006
2007
2006
$960,333
$916,167
$2,852,671
$1,864,460
$200,000
$1,240,000
$1,534,613
$1,043,514
$396,687
$607,463
$13,500
$55,789
$5,957,804
$5,727,393
$741,667
$701,657
$1,995,000
$1,394,053
$716,400
$1,339,911
$1,045,750
$705,165
$232,697
$231,862
$45,551
$42,691
$4,777,065
$4,415,339
$747,583
$615,000
$1,995,000
$675,000
$473,675
$590,928
$1,054,093
$580,466
$194,469
$168,627
$78,787
$37,722
$4,543,607
$2,667,743
1 No bonus was paid to a named executive offi cer except as part of a non-equity incentive plan.
2 No stock options were granted in 2007. A discussion of the assumptions used in calculating these values may be
found in Note 7 to our 2007 audited fi nancial statements on pages 43–44 of our annual report.
3 Payment for 2007 performance made in March 2008 under the Eli Lilly and Company Bonus Plan.
4 The amounts in this column are the change in pension value for each individual. No named executive offi cer received
preferential or above-market earnings on deferred compensation.
5 The table below shows the components of this column for 2007, which include the company match for each individ-
ual’s savings plan contributions, tax reimbursements, and perquisites.
Name
Mr. Taurel
Dr. Lechleiter
Dr. Paul
Mr. Armitage
Mr. Rice
Year
2007
2006
2007
2006
2007
2006
2007
2006
2007
2006
Savings Plan Match
Tax Reimbursements
Perquisites
Other
$103,045
$99,020
$68,945
$66,720
$13,500
$54,970
$44,500
$42,099
$44,855
$36,900
$2,7311
$1,3821
$1,8162
$2,0702
0
$8192
$1,0512
$5922
$15,0302,3
$8222
$109,268 4
$92,0074
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
$18,9025
0
Total “All Other
Compensation”
$215,044
$192,409
$70,761
$68,790
$13,500
$55,789
$45,551
$42,691
$78,787
$37,722
1 Tax reimbursements on income imputed to Mr. Taurel for his use of the corporate aircraft to attend outside
board meetings and for travel by his wife on the corporate aircraft to attend certain company functions in-
volving spouse participation.
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2 Tax reimbursements for travel by the executives’ spouses on the corporate aircraft to attend certain company
functions involving spouse participation.
3 For Mr. Rice, this amount includes $13,051 in tax reimbursements for the payment described in footnote 5
below.
4 These amounts include the incremental cost to the company of use of the corporate aircraft to attend outside
board meetings and one personal trip in 2007, offset by Mr. Taurel’s reimbursement under the time-share
agreement. The incremental cost of Mr. Taurel’s use of the corporate aircraft was $107,105 in 2007 and $91,069
in 2006. The amounts in this column also include Mrs. Taurel’s expenses to attend board functions that
included spouse participation. In addition, Mr. Taurel’s family members have occasionally accompanied him
on business trips, at no incremental cost to the company. We calculate the incremental cost to the company
of any personal use of the corporate aircraft based on the cost of fuel, trip-related maintenance, crew travel
expenses, on-board catering, landing fees, trip-related hangar and parking costs, and smaller variable costs,
offset by any time-share lease payments by the executive. Since the company-owned aircraft are used primar-
ily for business travel, we do not include the fi xed costs that do not change based on usage, such as pilots’
salaries, the purchase costs of the company-owned aircraft and the cost of maintenance not related to trips.
5 Reimbursement for an over-withholding of taxes by the company in a prior year when Mr. Rice was on an
overseas assignment.
We have no employment agreements with our named executive offi cers. See, however, the description of ad-
ditional years of service that may be credited to certain named executive offi cers upon retirement (pages 96–97).
The compensation plans under which the grants in the following table were made are generally described in
the Compensation Discussion and Analysis, beginning on page 81, and include the Eli Lilly and Company Bonus
Plan, a non-equity incentive plan, and the 2002 Lilly Stock Plan, which provides for performance awards, share-
holder value awards, stock options, restricted stock grants, and stock units.
Grants of Plan-Based Awards During 2007
Name
Grant Date
Compensation
Committee
Action Date
Mr. Taurel
—
2/9/2007 4
2/9/2007 5
—
12/18/2006
12/18/2006
Dr. Lechleiter
—
2/9/2007 4
2/9/2007 5
—
12/18/2006
12/18/2006
Dr. Paul
—
2/9/2007 4
2/9/2007 5
—
12/18/2006
12/18/2006
Mr. Armitage
—
2/9/2007 4
2/9/2007 5
—
12/18/2006
12/18/2006
Mr. Rice
—
2/9/2007 4
2/9/2007 5
—
12/18/2006
12/18/2006
Estimated Possible Payouts
Under Non-Equity
Incentive Plan Awards 1
Estimated Possible and Future
Payouts Under Equity
Incentive Plan Awards 2
Threshold
($)
Target
($)
Maximum
($)
Threshold
(# shares)
Target
(# shares)
Maximum
(# shares)
All Other
Option
Awards:
Number of
Securities
Underlying
Options 3
0
0
0
0
0
$2,146,771
$4,293,542
$1,149,083
$2,298,166
$816,283
$1,632,566
$556,250
$1,112,500
$560,688
$1,121,376
0
0
0
0
0
0
0
0
0
0
56,426
68,426
100,000
95,796
36,677
44,477
73,354
62,268
22,128
26,834
44,256
37,568
15,766
19,119
31,532
26,767
15,766
19,119
31,532
26,767
0
0
0
0
0
Grant Date
Fair Value
of Equity
Awards
$3,060,000
$3,060,000
$1,989,000
$1,989,000
$1,200,000
$1,200,000
$855,000
$855,000
$855,000
$855,000
1 These columns show the range of payouts targeted for 2007 performance under the Eli Lilly and Company Bonus
Plan as described in the section titled “Cash Incentive Bonuses” in the Compensation Discussion and Analysis.
The 2008 bonus payment for 2007 performance has been made based on the metrics described, at 188 percent of
target, and is shown in the Summary Compensation Table in the column titled “Non-Equity Incentive Plan Com-
pensation.”
2 These columns show the range of payouts targeted for 2007 performance under the 2002 Lilly Stock Plan as
described in the sections titled “Equity Incentives—Performance Awards” and “Equity Incentives—Shareholder
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Value Awards” in the Compensation Discussion and Analysis.
3 No stock options were granted to named executive offi cers in 2007.
4 These rows show performance award grants. The dollar amount recognized by the company for these perfor-
mance awards is shown in the Summary Compensation Table in the column titled “Stock Awards” and their valu-
ation assumptions are referenced in footnote 2 to that table. The 2007 performance award payout was made in
January 2008 and is shown in more detail below.
5 These rows show shareholder value award grants. The payout for the 2007 shareholder value award will be deter-
mined in January 2010.
Our performance awards granted in 2007 paid out in January 2008, and the named executive offi cers received
the following shares:
Name
Mr. Taurel
Dr. Lechleiter
Dr. Paul
Mr. Armitage
Mr. Rice
Performance Awards
Value on
December 31, 2007
100,000
$5,339,000
73,354
44,256
31,532
31,532
$3,916,370
$2,362,828
$1,683,493
$1,683,493
For 2007 performance, payouts were 200 percent of target. In order to receive a performance award payout,
a participant must have remained employed with the company through December 31, 2007 (except in the case of
death, disability, or retirement). In addition, an executive who was an executive offi cer at the time of grant and at
the time of payout received payment in shares of restricted stock. Non-preferential dividends are paid during the
one-year restriction period. Each executive was awarded the shares identifi ed above, and the shares will remain
restricted (and subject to forfeiture if the executive resigns) until the earlier of February 2009 or the executive’s
retirement. Mr. Taurel’s shares will vest upon his retirement from the company on December 31, 2008.
Our shareholder value awards granted in 2007 will pay out at the end of the three-year performance period
according to the grid as shown on page 87 of the Compensation Discussion and Analysis. At the end of 2007, the
award was on track to pay out at 40 percent of target.
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Outstanding Equity Awards at December 31, 2007
Option Awards
Stock Awards
Number of
Securities
Underlying
Unexercised
Options (#) 1
Exercisable
Number of
Securities
Underlying
Unexercised
Options (#) 1
Unexercisable
Option
Exercise
Price
($)
Option
Expiration
Date
Equity
Incentive
Plan Awards:
Number of
Unearned
Shares, Units
or Other
Rights That
Have Not
Vested
(#)
Equity
Incentive
Plan Awards:
Market or
Payout Value
of Unearned
Shares, Units
or Other
Rights That
Have Not
Vested
($)
68,4263
$3,653,264
Number of
Shares
or Units of
StockThat
Have Not
Vested 2
(#)
Market Value
of Shares or
Units
of Stock That
Have Not Vested 2
($)
100,000 4
96,120 5
$5,339,000
$5,131,846
400,000
350,000
350,000 6
175,000
350,000
350,000
240,000
50,000
200,000
120,000
120,000 7
60,000
10,000
100,000
80,000
50,000
120,000
50,000
46,000
23,000
75,900
25,000 9
46,000
25,000
80,000
80,000
23,800
7,000
23,100
14,000
25,000
11,200
10,000
5,000
12,000
10,000
5,700
216,867
255,621
140,964
127,811
72,289
85,207
50,000 9
25,000 9
54,217
53,254
30,000
27,108
23,077
$56.18
55.65
73.11
57.85
75.92
79.28
88.41
66.38
74.28
61.22
$56.18
55.65
73.11
57.85
75.92
79.28
88.41
88.41
66.38
74.28
$56.18
55.65
73.11
57.85
75.92
79.28
73.98
88.41
88.41
88.41
66.38
74.28
$56.18
55.65
73.11
57.85
75.92
79.28
73.98
66.38
$52.54
56.18
55.65
73.11
57.85
75.92
79.28
73.98
66.38
74.28
2/09/2016
2/10/2015
2/14/2014
2/15/2013
2/17/2012
10/04/2011
12/17/2010
10/16/2009
10/17/2008
5/30/2008
2/09/2016
2/10/2015
2/14/2014
2/15/2013
2/17/2012
10/04/2011
12/17/2010
12/17/2010
10/16/2009
10/17/2008
2/09/2016
2/10/2015
2/14/2014
2/15/2013
2/17/2012
10/04/2011
2/18/2011
12/17/2010
12/17/2010
12/17/2010
10/16/2009
10/17/2008
2/09/2016
2/10/2015
2/14/2014
2/15/2013
2/17/2012
10/04/2011
2/18/2011
10/16/2009
4/29/2016
2/09/2016
2/10/2015
2/14/2014
2/15/2013
2/17/2012
10/04/2011
2/18/2011
10/16/2009
10/17/2008
73,354 4
62,478 5
$3,916,370
$3,335,700
44,4773
$2,374,627
44,256 4
5,000 8
32,040 5
$2,362,828
$266,950
$1,710,616
26,834 3
$1,432,667
31,532 4
24,030 5
$1,683,493
$1,282,962
19,1193
$1,020,763
31,532 4
$1,683.493
19,1193
$1,020,763
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Name
Mr. Taurel
Dr. Lechleiter
Dr. Paul
Mr. Armitage
Mr. Rice
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1 The vesting date of each option is listed in the table below by expiration date:
Expiration Date
Vesting Date
Expiration Date
Vesting Date
04/29/2016
02/09/2016
02/10/2015
02/14/2014
02/15/2013
02/17/2012
05/01/2009
02/10/2009
02/11/2008
02/19/2007
02/17/2006
02/18/2005
10/04/2011
02/18/2011
12/17/2010
10/16/2009
10/17/2008
05/30/2008
10/03/2003
02/20/2004
12/18/2003
10/18/2002
10/19/2001
06/04/2001
2 These two columns show performance award shares paid in restricted shares with a holding period of one year.
The restricted stock shares pay dividends during the restriction period, but the dividends are not preferential.
3 Shares granted under the company’s Shareholder Value Award plan that will vest December 31, 2009. The number
of shares reported in the table refl ects the target payout amount, which will be made if the average stock price in
November and December 2009 is between $63.00 and $66.99. Actual payouts may vary from zero to 140 percent of
target. Had the performance period ended at year end, the payout would have been 40 percent of target.
4 Shares paid out in January 2008 for 2007 performance. These shares vest in February 2009.
5 Shares paid out in January 2007 for 2006 performance. These shares vested in February 2008.
6 Mr. Taurel transferred 348,683 shares of this option to a trust for the benefi t of his children, and these shares
vested on April 30, 2002. 149,172 shares of this option are held in trust for the benefi t of Mr. Taurel’s children, and
the remainder have been transferred back to Mr. Taurel.
7 Dr. Lechleiter transferred 118,683 shares of this option to a trust for the benefi t of his children, and these shares
vested on April 30, 2002. 50,734 shares of this option are held in trust for the benefi t of Dr. Lechleiter’s children,
and the remainder have been transferred back to Dr. Lechleiter.
8 These shares will vest December 20, 2010.
9 These options were granted outside of the normal annual cycle and vest in three installments, as follows: 25 per-
cent on December 19, 2005; 25 percent on December 18, 2008; and 50 percent on November 2, 2009.
Options Exercised and Stock Vested in 2007
Name
Mr. Taurel
Dr. Lechleiter
Dr. Paul
Mr. Armitage
Mr. Rice
Option Awards
Stock Awards 2
Number of Shares Acquired
on Exercise (#)
Value Realized
on Exercise ($) 1
Number of Shares Acquired
on Vesting (#)
Value Realized
on Vesting ($)
0
0
0
0
100,000
$480,020
0
0
0
0
64,690
32,345
24,564
13,478
0
$3,501,023
$1,750,511
$1,342,904
$729,429
0
1 Amounts refl ect the difference between the exercise price of the option and the market price at the time of exer-
cise.
2 Amounts refl ect the market value of the stock on the day the stock vested. These shares represent performance
awards issued in January 2006 for company performance in 2005, which were subject to forfeiture for one year
following issuance. For Dr. Paul, these columns include 3,000 shares of restricted stock, which vested on June 1,
2007.
Retirement Benefi ts
We maintain two programs to provide retirement income to all eligible U.S. employees, including executive offi cers:
• The Lilly Employee 401(k) Plan, a defi ned contribution plan qualifi ed under sections 401(a) and 401(k) of the
Internal Revenue Code. Eligible employees may elect to contribute a portion of their salary to the plan, and
the company provides matching contributions on the employees’ contributions up to 6 percent of base salary.
The matching contributions are in the form of Lilly stock. The employee contributions, company contributions,
and earnings thereon are paid out in accordance with elections made by the participant. See the Summary
Compensation Table on page 91 for information about company contributions to the named executive offi cers.
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• The Lilly Retirement Plan (the retirement plan), a tax-qualifi ed defi ned benefi t plan that provides monthly
retirement benefi ts to eligible employees. See the Summary Compensation Table on page 91 for additional
information about the value of these pension benefi ts.
Section 415 of the Internal Revenue Code generally places a limit on the amount of annual pension that can
be paid from a tax-qualifi ed plan ($180,000 in 2007) as well as on the amount of annual earnings that can be used
to calculate a pension benefi t ($225,000). However, since 1975 the company has maintained a non-tax-qualifi ed
retirement plan that pays eligible employees the difference between the amount payable under the tax-qualifi ed
plan and the amount they would have received without the qualifi ed plan’s limit. The nonqualifi ed retirement plan is
unfunded and subject to forfeiture in the event of bankruptcy.
The following table shows benefi ts that named executive offi cers are entitled to under the retirement plan.
Pension Benefi ts in 2007
Name
Mr. Taurel 2
Dr. Lechleiter 3
Dr. Paul 4
Mr. Armitage
Mr. Rice
Plan
tax-qualifi ed plan
nonqualifi ed plan
total
tax-qualifi ed plan
nonqualifi ed plan
total
tax-qualifi ed plan
nonqualifi ed plan
total
tax-qualifi ed plan
nonqualifi ed plan
total
tax-qualifi ed plan
nonqualifi ed plan
total
Number of Years of
Credited Service
Present Value of
Accumulated Benefi t ($) 1
Payments During
Last Fiscal year ($)
35
35
28
28
15
15 5
9
9 6
18
18
$1,169,470
$29,237,439
$30,406,909
$733,909
$6,563,736
$7,297,645
$252,137
$3,037,525
$3,289,662
$184,031
$795,456
$979,487
$231,424
$571,961
$803,385
0
0
0
0
0
1 The calculation of present value of accumulated benefi t assumes a discount rate of 6.75 percent, mortality RP
2000CH (post-retirement decrement only), and joint and survivor benefi t of 25 percent.
2 Mr. Taurel is currently eligible for full retirement benefi ts.
3 Dr. Lechleiter is currently eligible for early retirement. He qualifi es for approximately 11 percent less than his full
retirement benefi t. Early retirement benefi ts are further described below.
4 Dr. Paul is currently eligible for early retirement because he is over 55 years old and has more than 10 years of
service. He qualifi es for approximately 27 percent less than his full retirement benefi t. Early retirement benefi ts
are further described below.
5 Dr. Paul will be eligible for an additional 10 years of service, if he is employed by the company past age 60. This
potential additional service credit increased the present value of his nonqualifi ed pension benefi t shown above by
$1,174,879.
6 Mr. Armitage will be credited with approximately one year of service when he reaches age 60, making him eligible
to receive a reduced retirement benefi t under the company’s retirement program. Since this arrangement only
applies toward his eligibility for a benefi t, it does not change the present value of his nonqualifi ed pension benefi t.
The retirement plan benefi ts shown in the table are net present values. The benefi ts are not payable as a lump
sum; they are generally paid as a monthly annuity for the life of the retiree. The annual benefi t under the plan is
calculated using the average of the annual earnings for the highest fi ve out of the last 10 years of service (average
annual earnings). Annual earnings covered by the retirement plan consist of salary and bonus (amounts disclosed
in the company’s proxy statements for the relevant years) calculated for the amount of bonus paid (rather than
credited) and for the year in which earnings are paid (rather than earned or credited). In addition, for years prior to
2003, the calculation includes performance award payouts. The amount of the benefi t also depends on the retiree’s
age and years of service at the time of retirement. Benefi t calculations are based on “points,” with an employee’s
points equaling the sum of his or her age plus years of service. Employees who retire (i) at age 65 with at least fi ve
years of service, (ii) at age 62 with at least 80 points, or (iii) with 90 or more points receive an unreduced benefi t.
Employees may elect early retirement with reduced benefi ts under either of the following two options:
• Employees with between 80 and 90 points may retire with a benefi t that is reduced by three percent for each year
that the employee has left to reach 90 points or age 62.
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• Employees who have less than 80 points, but who have reached age 55 and have at least 10 years of service, may
retire with a benefi t that is reduced as described above and is further reduced by six percent for each year that
the employee has left to reach 80 points or age 65.
All U.S. retirees are entitled to medical insurance under the company’s plans. Retirees with spouses or un-
married dependents may elect that, upon the retiree’s death, the plan will pay survivor annuity benefi ts at either
25 or 50 percent of the retiree’s annuity benefi t. Election of the higher survivor benefi t will result in a lower annuity
payment during the retiree’s life.
Dr. Paul joined the company in 1993. Dr. Paul will receive 10 years of additional service credit if he remains
employed by the company past age 60, or is involuntarily terminated before he turns 60. When Mr. Armitage joined
the company in 1999, the company agreed to provide him with a retirement benefi t based on his actual years of
service and earnings at age 60. When Mr. Armitage reaches age 60 with 9.75 years of service, he will be treated
as though he has, for eligibility purposes only, 20 years of service. The additional service credits will make him
eligible to begin reduced benefi ts nine months earlier, but will not change the timing or amount of his unreduced
benefi ts (shown in the Pension Benefi ts in 2007 table on page 96). A grant of additional years of service credit to
any employee must be approved by the compensation committee of the board of directors.
Nonqualifi ed Deferred Compensation in 2007
Name
Mr. Taurel
Dr. Lechleiter
Dr. Paul
Mr. Armitage
Mr. Rice
Plan
nonqualifi ed savings
deferred compensation
total
nonqualifi ed savings
deferred compensation
total
nonqualifi ed savings
deferred compensation
total
nonqualifi ed savings
deferred compensation
total
nonqualifi ed savings
deferred compensation
total
Executive
Contributions in
Last Fiscal Year
($) 1
Registrant
Contributions in
Last Fiscal Year
($) 2
Aggregate
Earnings in
Last Fiscal Year
($)
Aggregate
Distributions in
Last Fiscal Year
($)
Aggregate
Balance at Last
Fiscal Year End
($) 3
$89,545
—
$89,545
$55,445
$372,520
$427,965
—
—
0
$31,000
$690,703
$721,703
$31,355
—
$31,355
$89,545
—
$89,545
$55,445
—
$55,445
—
—
0
$31,000
—
$31,000
$31,355
—
$31,355
$149,079
$464,186
$613,265
$42,801
$154,615
$197,416
$38,821
—
$38,821
$18,646
$123,219
$141,865
$7,670
—
$7,670
$2,924,791
$8,551,063
$11,475,854
$866,467
$2,917,168
$3,783,635
$689,318
—
$689,318
$370,254
$2,397,663
$2,767,917
$185,495
—
$185,495
0
0
0
0
0
1 The amounts in this column are also included in the Summary Compensation Table on page 91, in the “Salary” col-
umn (nonqualifi ed savings) or the “Non-Equity Incentive Plan Compensation” column (deferred compensation).
2 The amounts in this column are also included in the Summary Compensation Table on page 91, in the “All Other
Compensation” column as a portion of the savings plan match.
3 Of the totals in this column, the following amounts have previously been reported in the Summary Compensation
Table for this year and for previous years:
Name
Mr. Taurel
Dr. Lechleiter
Dr. Paul
Mr. Armitage
Mr. Rice
2007 ($)
$179,090
$483,410
0
$752,703
$62,710
Previous Years ($)
Total ($)
$3,341,875
$2,182,887
$218,711
$1,867,372
$47,400
$3,520,965
$2,666,297
$218,711
$2,620,075
$110,110
The Nonqualifi ed Deferred Compensation in 2007 table above shows information about two company pro-
grams: a nonqualifi ed savings plan and a deferred compensation plan. The nonqualifi ed savings plan is designed
to allow each executive to contribute up to 6 percent of his or her base salary, and receive a company match,
beyond the contribution limits prescribed by the IRS with regard to 401(k) plans. This plan is administered in the
same manner as the company 401(k) Plan, with the same participation and investment elections, and all employ-
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ees are eligible to participate. Executive offi cers and other executives may also defer receipt of all or part of their
cash compensation under the company’s deferred compensation plan. Amounts deferred by executives under this
program are credited with interest at 120 percent of the applicable federal long-term rate as established for the
preceding December by the U.S. Treasury Department under Section 1274(d) of the Internal Revenue Code with
monthly compounding, which was 5.7 percent for 2007 and is 5.5 percent for 2008. Participants may elect to receive
the funds in a lump sum or in up to 10 annual installments following retirement, but may not make withdrawals
during their employment, except in the event of hardship as approved by the compensation committee. All deferral
elections and associated distribution schedules are irrevocable. Both plans are unfunded and subject to forfeiture
in the event of bankruptcy.
Potential Payments Upon Termination or Change in Control
The following table describes the potential payments and benefi ts under the company’s compensation and benefi t
plans and arrangements to which the named executive offi cers would be entitled upon termination of employment.
Except for (i) certain terminations following a change in control of the company, as described below, and (ii) certain
pension arrangements as shown below and described under “Retirement Benefi ts” above, there are no agreements,
arrangements, or plans that entitle named executive offi cers to severance, perquisites, or other enhanced benefi ts
upon termination of their employment. Any agreement to provide such payments or benefi ts to a terminating execu-
tive offi cer (other than following a change in control) would be at the discretion of the compensation committee.
Potential Payments Upon Termination of Employment
Cash Severance
Payment
Incremental
Pension Benefi t
(present value)
Continuation of
Medical / Welfare
Benefi ts (present
value)
Acceleration and
Continuation of
Equity Awards
(unamortized
expense as of
12/31/07)
Excise Tax
Gross-Up
Total
Termination
Benefi ts
Mr. Taurel
• Voluntary retirement
• Involuntary termination
• Involuntary or good reason
termination after change in control
(CIC)
Dr. Lechleiter
• Voluntary retirement
• Involuntary termination
• Involuntary or good reason
termination after CIC
Dr. Paul
• Voluntary retirement
• Involuntary termination
• Involuntary or good reason
termination after CIC
Mr. Armitage
• Voluntary termination
• Involuntary termination
• Involuntary or good reason
termination after CIC
Mr. Rice
• Voluntary termination
• Involuntary termination
• Involuntary or good reason
termination after CIC
0
0
$11,580,950
0
0
0
0
0 1
0
0
0
0
0
0
$24,0002
$487,102
0
0
0
0
0
0
0
0
0
$6,661,440
$1,347,065
$24,000
$316,617
$3,301,506
0
0
$12,092,052
0
0
$11,650,628
0
0
0
0
$3,141,258 3
$89,577 3
0
0
0
0
0
$3,230,835
$5,029,728
$4,108,206 3
$113,577 3
$457,972
$3,888,845
$13,598,328
0
0
0
0
0
0
0
0
0
0
0
0
$3,603,432
$720,138
$242,082
$3,102,557
$2,171,275
$9,839,484
0
0
0
0
0
0
0
0
0
0
0
0
$3,637,654
$104,298
$24,000
$1,845,095
$1,697,147
$7,308,194
1 See “Change-in-Control Severance Pay Program—Incremental pension benefi t” on page 100.
2 See “Accrued Pay and Regular Retirement Benefi ts” and “Change-in-Control Severance Pay Program—Continua-
tion of medical and welfare benefi ts” on pages 99–100.
3 These amounts refl ect an additional 10 years of service credit that would be credited to Dr. Paul upon an invol-
untary termination, other than for cause, should it occur before he reaches age 60 (see pages 96–97 for more
information about Dr. Paul’s retirement benefi ts).
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Accrued Pay and Regular Retirement Benefi ts. The amounts shown in the previous table do not include payments
and benefi ts to the extent they are provided on a non-discriminatory basis to salaried employees generally upon
termination of employment. These include:
• Accrued salary and vacation pay.
• Regular pension benefi ts under the Lilly Retirement Plan and the nonqualifi ed retirement plan. See “Retirement
Benefi ts” on pages 95–97. The amounts shown in the table above as “Incremental Pension Benefi t” are explained
below.
• Welfare benefi ts provided to all U.S. retirees, including retiree medical and dental insurance. The amounts
shown in the table above as “Continuation of Medical / Welfare Benefi ts” are explained below.
• Distributions of plan balances under the Lilly 401(k) Plan and the nonqualifi ed savings plan. See the narrative
following the Nonqualifi ed Deferred Compensation in 2007 table on pages 97–98 for information about the 401(k)
plan, the deferred compensation plan, and the nonqualifi ed savings plan.
• The value of accelerated vesting of certain unvested equity grants upon retirement. Under the company’s stock
plans, employees who terminate employment while retirement-eligible receive accelerated vesting of unvested
stock options (except for options granted in the 12 months before retirement, which are forfeited), outstanding
performance awards and shareholder value awards (which are paid on a reduced basis for time worked during
the award period), and restricted stock awarded in payment of previous performance awards.
• The value of option continuation upon retirement. When an employee terminates prior to retirement, his or her
stock options are terminated 30 days thereafter. However, when a retirement-eligible employee terminates, his or
her options remain in force until the earlier of fi ve years after retirement or the option’s normal expiration date.
Deferred Compensation. The amounts shown in the table do not include distributions of plan balances under the
Lilly deferred compensation plan. Those amounts are shown in the Nonqualifi ed Deferred Compensation in 2007
table on page 97.
Death and Disability. A termination of employment due to death or disability does not entitle the named executive
offi cers to any payments or benefi ts that are not available to salaried employees generally.
Change-in-Control Severance Pay Program. As described in the Compensation Discussion and Analysis under
“Severance Benefi ts” on page 89, the company maintains a change-in-control severance pay program for nearly
all employees, including the named executive offi cers (the “CIC Program”). The CIC Program defi nes a change in
control very specifi cally, but generally the term includes the occurrence of, or entry into an agreement to do one of
the following: (a) acquisition of 15 percent or more of the company’s stock; (b) replacement by the shareholders of
one third or more of the board of directors; (c) consummation of a merger, share exchange, or consolidation of the
company; or (d) liquidation of the company or sale or disposition of all or substantially all of its assets. The amounts
shown in the table for “involuntary or good reason termination” following a change in control are based on the fol-
lowing assumptions and plan provisions:
• Covered terminations. The table assumes a termination of employment that is eligible for severance under the
terms of the current plan, based on the named executive’s compensation, benefi ts, age, and service credit at
December 31, 2007. Eligible terminations include an involuntary termination for reasons other than cause, or a
voluntary termination by the executive for good reason, within two years following the change in control.
—A termination of an executive offi cer by the company is for cause if it is for any of the following reasons: (i) the
employee’s willful and continued refusal to perform, without legal cause, his or her material duties, resulting
in demonstrable economic harm to the company; (ii) any act of fraud, dishonesty, or gross misconduct
resulting in signifi cant economic harm or other signifi cant harm to the business reputation of the company;
or (iii) conviction of or the entering of a plea of guilty or nolo contendere to a felony.
—A termination by the executive offi cer is for good reason if it results from (i) a material diminution in the
nature or status of the executive’s position, title, reporting relationship, duties, responsibilities or authority,
or the assignment to him or her of additional responsibilities that materially increase his or her workload;
(ii) any reduction in the executive’s then-current base salary; (iii) a material reduction in the executive’s
opportunities to earn incentive bonuses below those in effect for the year prior to the change in control; (iv) a
material reduction in the executive’s employee benefi ts from the benefi t levels in effect immediately prior to
the change in control; (v) the failure to grant to the executive stock options, stock units, performance shares,
or similar incentive rights during each twelve (12) month period following the change in control on the basis
of a number of shares or units and all other material terms at least as favorable to the executive as those
rights granted to him or her on an annualized average basis for the three (3) year period immediately prior to
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the change in control; or (vi) relocation of the executive by more than fi fty (50) miles.
• Cash severance payment. Represents the CIC Program benefi t of two times the 2007 annual base salary plus two
times cash bonus for 2007 under the Eli Lilly and Company Bonus Plan.
• Incremental pension benefi t. Represents the present value of an incremental nonqualifi ed pension benefi t of
two years of age credit and two years of service credit that is provided under the CIC Program. The following
standard actuarial assumptions were used to calculate each individual’s incremental pension benefi t:
Discount rate:
6.75 percent
Mortality (post-retirement only):
RP 2000CH
Joint & survivor benefi t:
25% of pension
Because Mr. Taurel already qualifi es for a full pension benefi t, the additional age credit and service credit do not
increase his benefi t. For Dr. Paul, the amounts in the table above refl ect the 10 years of additional service credit
described on pages 96–97.
• Continuation of medical and welfare benefi ts. Represents the present value of the CIC Plan’s guarantee for
two years following a covered termination of continued coverage equivalent to the company’s current active
employee medical, dental, life, and long-term disability insurance. For two of the three retirement-eligible
employees, Mr. Taurel and Dr. Lechleiter, there is limited incremental benefi t under the CIC Plan because they
would be entitled to equivalent medical and dental coverage in the ordinary course as retirees regardless of the
reason for termination. For Dr. Paul, the amounts in the table refl ect the 10 years of additional service credit
described on pages 96–97. The same actuarial assumptions were used to calculate continuation of medical and
welfare benefi ts as were used to calculate incremental pension benefi ts, with the addition of an assumed COBRA
rate of $12,000 per year.
• Acceleration and continuation of equity awards. Under the CIC Plan, upon a covered termination, any unvested stock
options, restricted stock, or other equity awards would vest, and options would be exercisable for up to three
years following termination. Payment of the Shareholder Value Award is accelerated in the case of a change in
control in which Lilly is not the surviving entity. For the three retirement-eligible employees, Mr. Taurel and Drs.
Lechleiter and Paul, the only other equity award receiving accelerated vesting and term extension because of
the CIC Plan would be 5,000 shares of restricted stock held by Dr. Paul; all other unvested equity awards (with
the exception of the SVA) automatically vest upon retirement regardless of reason. The amounts in this column
represent the previously unamortized expense that would be recognized in connection with the acceleration of
unvested equity grants. In addition, the two named executive offi cers who are not retirement-eligible, Messrs.
Armitage and Rice, would receive the benefi t under the CIC Plan of continuation of their outstanding stock
options for up to three years following termination of employment. There would be no incremental expense to the
company for this continuation because the option would already have been fully expensed.
• Excise tax gross-up. Upon a change in control, employees may be subject to certain excise taxes under Section
280G of the Internal Revenue Code. The company has agreed to reimburse the affected employees for those
excise taxes as well as any income and excise taxes payable by the executive as a result of the reimbursement.
The amounts in the table are based on a 280G excise tax rate of 20 percent and a 40 percent federal, state, and
local income tax rate.
Payments Upon Change in Control Alone. The CIC Program is a “double trigger” program, meaning payments are
made only if the employee suffers a covered termination of employment within two years following the change in
control. Employees do not receive payments upon a change in control alone, except that upon consummation of a
change in control a partial payment of outstanding performance awards would be made, reduced to refl ect only the
portion of the year worked prior to the change in control. For example, if a change in control occurred on June 30,
the employee would receive one-half of the value of the performance award, calculated based on the company’s
then-current fi nancial forecast for the year. Likewise, in the case of a change in control in which Lilly is not the
surviving entity, the SVA will pay out based on the change-in-control stock price and prorated for the portion of the
three-year performance period elapsed.
Related-Person Transaction
As noted above, under board policy, for security reasons the company aircraft is made available to Mr. Taurel for
all travel. The company has entered into a time-share arrangement with Mr. Taurel in connection with his per-
sonal use of company aircraft. Under the time-share agreement, Mr. Taurel leases the company aircraft, including
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crew and fl ight services, for personal fl ights. He pays a time-share fee based on the company’s cost of the fl ight
but capped at the greater of (i) an amount equivalent to fi rst-class airfare for the relevant fl ight (if commercially
available) and (ii) the Standard Industry Fare Levels as established by the Internal Revenue Service for purposes of
determining taxable fringe benefi ts.
Ownership of Company Stock
Common Stock Ownership by Directors and Executive Offi cers
The following table sets forth the number of shares of company common stock benefi cially owned by the directors,
the named executive offi cers, and all directors and executive offi cers as a group, as of February 4, 2008.
The table shows shares held by named executives in the Lilly Employee 401(k) Plan, shares credited to the
accounts of outside directors in the Lilly Directors’ Deferral Plan, and total shares benefi cially owned by each
individual, including the shares in the respective plans. In addition, the table shows shares that may be purchased
pursuant to stock options that are exercisable within 60 days of February 4, 2008.
Name
Robert A. Armitage
Sir Winfried Bischoff
J. Michael Cook
Michael L. Eskew
Martin S. Feldstein, Ph.D.
George M.C. Fisher
J. Erik Fyrwald
Alfred G. Gilman, M.D., Ph.D.
Karen N. Horn, Ph.D.
John C. Lechleiter, Ph.D.
Ellen R. Marram
Steven M. Paul, M.D.
Franklyn G. Prendergast, M.D., Ph.D.
Derica W. Rice
Kathi P. Seifert
Sidney Taurel
401(k) Plan Shares
1,383
—
—
—
—
—
—
—
—
13,040
—
47
—
4,850
—
16,981
Directors’ Deferral
Plan Shares 1
Total Shares Owned
Benefi cially 2
Stock Options
Exercisable Within
60 Days of
February 4, 2008
—
11,232
10,702
0
9,596
18,536
9,268
17,159
29,944
—
9,596
—
22,804
—
18,837
—
73,317
13,232
12,502
0
10,596
28,536
9,368
17,159
29,944
236,4453
10,596
58,435
22,804
69,207
22,370
281,154
11,200
—
—
8,400
11,200
—
14,000
14,000
867,811
5,600
496,107
14,000
101,977
14,000
1,108,586 4
2,520,621
All directors and executive offi cers as a group (22 people):
2,074,960
1 See description of the Lilly Directors’ Deferral Plan, pages 76–77.
2 Unless otherwise indicated in a footnote, each person listed in the table possesses sole voting and sole invest-
ment power with respect to the shares shown in the table to be owned by that person. No person listed in the
table owns more than 0.10 percent of the outstanding common stock of the company. All directors and executive
offi cers as a group own 0.18 percent of the outstanding common stock of the company. 1,800 of Mr. Cook’s shares
were on deposit in a margin account as of February 4, 2008.
3 The shares shown for Dr. Lechleiter include 13,470 shares that are owned by a family foundation for which he is a di-
rector. Dr. Lechleiter has shared voting power and shared investment power over the shares held by the foundation.
4 The shares shown for Mr. Taurel include 18,545 shares that are owned by a family foundation for which he is a
director. Mr. Taurel has shared voting power and shared investment power over the shares held by the foundation.
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Principal Holders of Stock
To the best of the company’s knowledge, the only benefi cial owners of more than 5 percent of the outstanding
shares of the company’s common stock are the shareholders listed below:
Name and Address
Lilly Endowment, Inc. (the “Endowment”)
2801 North Meridian Street
Indianapolis, Indiana 46208
Capital World Investors
333 South Hope Street
Los Angeles, California 90071
Wellington Management Company, LLP
75 State Street
Boston, Massachusetts 02109
Number of Shares
Benefi cially Owned
137,505,804
(as of 2/4/08)
80,085,190
(as of 12/31/07)
67,709,168
(as of 12/31/07)
Percent of
Class
12.1%
7.1%
6.0%
The Endowment has sole voting and sole investment power with respect to its shares. The board of directors of the
Endowment is composed of Mr. Thomas M. Lofton, chairman; Mr. N. Clay Robbins, president; Mrs. Mary K. Lisher;
Drs. Otis R. Bowen and William G. Enright; and Messrs. Daniel P. Carmichael, Eli Lilly II, and Eugene F. Ratliff
(Emeritus Director). Each of the directors is, either directly or indirectly, a shareholder of the company.
Capital World Investors is a division of Capital Research and Management Company. It has sole voting power
with respect to 4,350,000 shares (approximately 0.38 percent of shares outstanding) and sole investment power
with respect to all of its shares.
Wellington Management Company, LLP acts as investment advisor to various clients. It has shared voting
power with respect to 21,625,613 shares (approximately 1.9 percent of shares outstanding) and shared investment
power with respect to all of its shares.
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Items of Business to Be Acted Upon at the Meeting
Item 1. Election of Directors
Under the company’s articles of incorporation, the board is divided into three classes with approximately one-third
of the directors standing for election each year. The term for directors elected this year will expire at the annual
meeting of shareholders held in 2011. Each of the nominees listed below has agreed to serve that term. If any
director is unable to stand for election, the board may, by resolution, provide for a lesser number of directors or
designate a substitute. In the latter event, shares represented by proxies may be voted for a substitute director.
The board recommends that you vote FOR each of the following nominees:
• Michael L. Eskew
• Alfred G. Gilman, M.D., Ph.D.
• Karen N. Horn, Ph.D.
• John C. Lechleiter, Ph.D.
Biographical information about these nominees may be found on pages 65–66 of this proxy statement. Information
about certain legal matters may be found on page 115.
Item 2. Proposal to Ratify the Appointment of Principal Independent Auditors
The audit committee has appointed the fi rm of Ernst & Young LLP as principal independent auditors for the com-
pany for the year 2008. In accordance with the bylaws, this appointment is being submitted to the shareholders for
ratifi cation. Ernst & Young served as the principal independent auditors for the company in 2007. Representatives
of Ernst & Young are expected to be present at the annual meeting and will be available to respond to questions.
Those representatives will have the opportunity to make a statement if they wish to do so.
102102
The board recommends that you vote FOR ratifying the appointment of Ernst & Young LLP as principal indepen-
dent auditors for 2008.
Item 3. Proposal to Amend the Company’s Articles of Incorporation to Provide for Annual Election of Directors
The company’s Amended Articles of Incorporation currently provide that the board of directors is divided into three
classes, with each class elected every three years. In December 2006, on the recommendation of the directors and
corporate governance committee, the board unanimously adopted resolutions approving, and recommending to the
shareholders for approval, amendments to provide for the annual election of directors. This proposal was brought
before shareholders at the company’s annual meeting of shareholders in April 2007, and received the vote of over
75 percent of the outstanding shares; however, the proposal required the vote of 80 percent of the outstanding
shares to pass. In December 2007, the board again unanimously adopted resolutions recommending these amend-
ments to shareholders for approval.
If approved, this proposal will become effective upon the fi ling of Amended and Restated Articles of Incor-
poration containing these amendments with the Secretary of State of Indiana, which the company intends to do
promptly after shareholder approval is obtained. Directors elected prior to the effectiveness of the amendments
will stand for election for one-year terms once their then-current terms expire. This means that directors whose
terms expire at the 2009 and 2010 annual meetings of shareholders would be elected for one-year terms, and
beginning with the 2011 annual meeting, all directors would be elected for one-year terms at each annual meeting.
In addition, in the case of any vacancy on the board occurring after the 2008 annual meeting, including a vacancy
created by an increase in the number of directors, the vacancy would be fi lled by interim election of the board, with
the new director to serve a term ending at the next annual meeting. At all times, directors are elected to serve for
their respective terms and until their successors have been elected and qualifi ed. This proposal would not change
the present number of directors, and it would not change the board’s authority to change that number and to fi ll
any vacancies or newly created directorships.
Article 9(b) of the company’s Amended Articles of Incorporation contains the provisions that will be affected if
this proposal is adopted. This article, set forth in Appendix A to this proxy statement, shows the proposed changes
with deletions indicated by strike-outs and additions indicated by underlining. The board has also adopted con-
forming amendments to the company’s bylaws, to be effective immediately upon the effectiveness of the amend-
ments to the Amended Articles of Incorporation.
Background of Proposal
The proposal is a result of ongoing review of corporate governance matters by the board. The board, assisted by
the directors and corporate governance committee, considered the advantages and disadvantages of maintaining
the classifi ed board structure. The board considered the view of some shareholders who believe that classifi ed
boards have the effect of reducing the accountability of directors to shareholders because classifi ed boards limit
the ability of shareholders to evaluate and elect all directors on an annual basis. The election of directors is the
primary means for shareholders to infl uence corporate governance policies. The board gave considerable weight
to the approval at the 2006 annual meeting of a shareholder proposal requesting that the board take all necessary
steps to elect the directors annually, and to the 75 percent favorable vote for management’s proposal in 2007.
The board also considered benefi ts of retaining the classifi ed board structure, which has a long history in
corporate law. Proponents of a classifi ed structure believe it provides continuity and stability in the management
of the business and affairs of a company because a majority of directors always have prior experience as directors
of the company. Proponents also assert that classifi ed boards may enhance shareholder value by forcing an entity
seeking control of a target company to initiate arms-length discussions with the board of that company, because
the entity cannot replace the entire board in a single election. While the board recognizes those potential benefi ts,
it also notes that even without a classifi ed board, the company has other means to compel a takeover bidder to
negotiate with the board, including certain “supermajority” vote requirements in its Amended Articles of Incor-
poration (as described in the company’s response to Item 8 on pages 112–113), other provisions of its articles and
bylaws, and certain provisions of Indiana law. In addition, the company has a shareholder rights plan. However, the
plan will expire in July 2008, and the board does not intend to renew it.
The directors and corporate governance committee and the board heard advice from outside governance and
legal experts on the annual election of directors. On the recommendation of the committee, the board approved
the amendments, and determined to recommend that shareholders approve the amendments to the company’s
Amended Articles of Incorporation to provide for the annual election of directors. Although this proposal did not
pass in 2007, the board continues to support this change and believes that by taking this action, it can provide
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shareholders further assurance that the directors are accountable to shareholders while maintaining appropriate
defenses to respond to inadequate takeover bids.
Vote Required
The affi rmative vote of at least 80 percent of the outstanding common shares is needed to pass this proposal.
The board recommends that you vote FOR amending the company’s articles of incorporation to provide for an-
nual election of directors.
Item 4. Proposal to Amend the Company’s Articles of Incorporation to Provide for Election of Directors by Major-
ity Vote
On the recommendation of the directors and corporate governance committee, the board has unanimously adopted
resolutions approving, and recommending to the shareholders for approval, amendments to the Amended Articles
of Incorporation to change the standard of election in uncontested elections of directors to a majority of votes cast.
Please see Appendix A to this proxy statement for the text of the proposed new Article 15.
Background of Proposal
Indiana law provides that, unless otherwise specifi ed by the Articles of Incorporation, directors are elected by a
plurality of votes cast. Lilly’s Amended Articles of Incorporation do not specify otherwise; therefore, directors are
elected by a plurality. Under this standard, director nominees with the most votes cast in their favor are elected
to the board, notwithstanding the number of votes withheld against a director nominee. Thus, a director can be
elected even though a majority of shares voted oppose his or her election.
The plurality standard has been the norm for U.S. corporations for many years. Recently, however, many
shareholders have called for changes in the director election standards to make director elections more meaning-
ful. In 2005, Lilly and several other leading companies addressed this concern by adopting a director resignation
policy, which calls for any director who fails to receive a majority of favorable votes to tender his or her resigna-
tion, subject to a determination by the board whether to accept the resignation. The board believes that now is the
right time to take the next step in assuring that shareholders have a clear voice in electing directors by moving to a
majority vote standard for uncontested elections.
Under Indiana law, directors are elected to serve for their respective terms and until their successors have
been elected and qualifi ed. Thus, under a majority vote standard, an incumbent director who fails to receive a
majority of votes cast would not be elected, but would continue to serve as a “holdover” director. However, under
amendments to the company’s Bylaws which the board has adopted subject to shareholder approval of this Item 4,
the unelected director would be required to offer to resign immediately. The board, with the advice of the directors
and corporate governance committee, would determine the appropriate responsive action and communicate its
decision, and its underlying rationale, to shareholders within 90 days of certifi cation of the election results. If the
resignation is accepted, the board may decide to fi ll any resulting vacancy or decrease the number of directors.
The amendments provide that in a contested election—an election in which the number of nominees exceeds
the number of directors to be elected—the plurality standard will continue to apply.
Effective Time
If approved, the Amended and Restated Articles of Incorporation will be effective upon fi ling with the State of Indi-
ana, which the company intends to do promptly after shareholder approval is obtained.
Vote Requirement
The amendments will be adopted if the votes cast for the amendment exceed the votes cast against the amendment.
The board recommends that you vote FOR amending the company’s articles of incorporation to provide for elec-
tion of directors by majority vote.
Item 5. Amendment of the 2002 Lilly Stock Plan
Stock incentive plans have been an integral part of the company’s compensation programs for more than 50 years.
These plans enable the company to attract and retain top talent and focus employees on creating and sustaining
shareholder value through increased employee stock ownership. In 2002, the board and the shareholders adopted
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the 2002 Lilly Stock Plan (“Plan”). The board now recommends that the shareholders approve certain amendments
to the Plan, primarily to extend its termination date and add additional shares that may be granted under the Plan.
Overview of Plan
Under the Plan all employees of the company are eligible to participate. The Compensation Committee of the board
(the “Committee”) may make grants to offi cers and employees at its discretion. The Plan authorizes the grant of up
to 80,000,000 shares plus unused shares under prior shareholder-approved stock plans.
The Committee may grant stock options, stock appreciation rights, performance awards, including sharehold-
er value awards, restricted stock grants and stock units to employees. The Board may grant stock options under
the Plan to nonemployee directors. The Plan is designed to maximize the deductibility of stock options and perfor-
mance awards under section 162(m) of the Internal Revenue Code of 1986, as amended (the “Code”).
Overview of Amendments
The board has approved, and recommends that the shareholders approve, the following changes to the Plan:
• extend the term of the Plan by eight years (from 2012 to 2020)
• increase the number of shares that may be granted during the life of the Plan by 39,000,000
• clarify the circumstances under which unused shares from expired or terminated grants may be added back to
the Plan for future grants
• eliminate or decrease share limits on certain types of grants that may be made under the Plan in the aggregate
• raise share limits on certain types of grants that may be made to individuals
• eliminate dollar-denominated performance awards
• allow stock units to be paid in cash
• miscellaneous clarifi cations to Plan language.
All proposed changes to the Plan are shown in Appendix B to this proxy statement, with new language indi-
cated by underlining and deleted language indicated by strike-outs. In addition, the most signifi cant changes are
described in more detail below.
Shares Subject to Plan
The maximum number of shares of Lilly stock that may be issued or transferred for grants under the Plan is the
sum of:
• 80,000,000 shares;
• 5,243,448 shares that were available under the previous shareholder-approved plan (the 1998 Lilly Stock Plan) at the
time that plan terminated in April 2002;
• any shares subject to grants under the Plan or prior shareholder-approved stock plans (the 1989, 1994, and 1998 Lilly
Stock Plans) that are not issued or transferred due to termination, lapse, or forfeiture of the grant; and
• any shares exchanged by grantees as payment to the company of the exercise price of stock options granted under the
Plan or prior shareholder approved stock plans.
The maximum number is subject to adjustment for stock splits, stock dividends, spin offs, reclassifi cations,
or other relevant changes affecting Lilly stock. There are currently approximately 46,577,743 shares available for
issue or transfer.
Proposed Amendments:
• Increase the maximum number of shares to 119,000,000, an increase of 39,000,000 shares. We anticipate that
this will provide suffi cient shares for several years of grants.
• Allow the add-back of shares withheld by the company for taxes upon the exercise of stock options or the
vesting of other grants. The number of shares that would be added back under this provision is not expected
to be material.
Grants Under the Plan
Under the Plan all employees of the company, including offi cers, and all members of the board are eligible to par-
ticipate. Currently approximately 40,500 employees, including all 10 executive offi cers, are eligible to participate.
The number of eligible employees and grantees will vary from year to year. There are currently 11 nonemployee
directors.
Stock Options and Stock Appreciation Rights. The Committee may grant nonqualifi ed options, incentive stock
options, or other tax favored stock options under the Code. The Committee establishes the option price, which may
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not be less than 100 percent of the fair market value of the stock on the date of grant. Options may not be repriced.
The Committee also establishes the vesting date and the term of the option.
The Committee may also grant stock appreciation rights (“SARs”)—the right to receive an amount based on
appreciation in the fair market value of shares of Lilly stock over a base price. If granted without a related stock
option, the committee establishes the base price of the SARs, which may not be less than 100 percent of the fair
market value of the stock on the date of grant, and the settlement or exercise date, which may not be more than
eleven years after the grant date. If granted in connection with a stock option, the holder of SARs may, upon exer-
cise, surrender the related options and receive payment, in the form of Lilly stock, equal to the excess of the the
fair market value of Lilly stock over the exercise price in the date of exercise multiplied by the number of shares
exercised. The price and term of the SARs mirror those of the related stock option, and the SARs automatically
terminate to the extent the related options are exercised. Effectively, these awards give the holder the benefi t of
the related stock options (in the form of shares of Lilly stock) without requiring payment of the exercise price.
A maximum of 60,000,000 shares may be issued under the Plan in the form of incentive stock options. No
grantee may receive options and SARs, considered together, for more than 2,500,000 shares under the Plan in any
period of three consecutive calendar years.
Proposed Amendments:
• Decrease the incentive stock option limit to 30,000,000 shares.
• Increase the individual limit to 3,500,000 shares in any period of three consecutive calendar years.
The incentive stock option limit is being reduced in light of expected grant patterns. The increase in the
individual limit will increase fl exibility of plan administration.
Performance Awards. The Committee may grant performance awards under which payment is made in shares
of Lilly stock, cash, or both if the fi nancial performance of the company or a subsidiary, division, or other business
unit of the company selected by the Committee meets certain performance goals during an award period. The
Committee establishes the performance goals at the beginning of the award period based on one or more perfor-
mance goals specifi ed in the Plan. The material terms of those performance goals are:
• earnings per share
• net income
• divisional income
• corporate or divisional net sales
• EVA® (after-tax operating profi t less the annual total cost of capital)
• Market Value Added (the difference between a company’s fair market value, as refl ected primarily in its stock
price, and the economic book value of capital employed)
• any of the foregoing goals before the effect of acquisitions, divestitures, accounting changes, and restructuring
and special charges
• total shareholder return
• other Lilly stock price goals.
The Committee also establishes the award period (four or more consecutive fi scal quarters), the threshold,
target and maximum performance levels, and the number of shares or dollar amounts payable at various perfor-
mance levels from the threshold to the maximum. In order to receive payment, a grantee must generally remain
employed by the company to the end of the award period. The Committee may impose additional conditions on a
grantee’s entitlement to receive payment under a performance award.
At any time prior to payment, the Committee can adjust awards for the effect of unforeseen events that have
a substantial effect on the performance goals and would otherwise make application of the performance goals
unfair. However, the Committee may not increase the amount that would otherwise be payable to individuals who
are subject to Section 162(m) of the Code.
A maximum of 18,000,000 shares may be issued under the Plan in the form of performance awards. Awards
may be denominated either in shares of Lilly stock (“Stock Performance Awards”) or in dollar amounts (“Dollar
Performance Awards”). The maximum number of shares that may be received by an individual in payment of Stock
Performance Awards in any calendar year is 100,000. As to Dollar Performance Awards, the maximum payment
to an individual in any calendar year is $8,000,000. The Committee can elect to pay cash in lieu of part or all of the
shares of Lilly stock payable under a Stock Performance Award, and such cash payment is counted as a payment of
shares (based on the market value of Lilly stock on the payment date) for purposes of determining compliance with
the 100,000-share limit for Stock Performance Awards.
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Proposed Amendments:
• Eliminate the 18,000,000-share limit. This limit was adopted at a time when performance awards created
a greater accounting expense to the company than stock options. With changes in accounting rules, the
expense of the different types of grants is comparable, and therefore the limit no longer serves its intended
purpose of minimizing the accounting cost of the Plan.
• Raise the individual limit from 100,000 to 600,000 shares annually. This change is also necessary to allow the
grant of both traditional performance awards and SVAs under the current program design.
• Eliminate Dollar Performance Awards. We have not granted Dollar Performance Awards for many years and
do not contemplate granting them in the future.
Restricted Stock Grants or Stock Units. The Committee may also issue or transfer shares under a restricted
stock grant. The grant will set forth a restriction period during which the shares may not be transferred. If the
grantee’s employment terminates during the restriction period, the grant terminates and the shares are returned
to the company. However, the Committee can provide complete or partial exceptions to that requirement as it
deems equitable. If the grantee remains employed beyond the end of the restriction period, the restrictions lapse
and the shares become freely transferable.
The Committee may grant stock unit awards subject to vesting and transfer restrictions and conditions of
payment determined by the Committee. The value of each stock unit equals the fair market value of Lilly stock and
may include the right to receive the equivalent of dividends on the shares granted. Payment is made in the form of
Lilly stock.
A maximum of 3,000,000 shares of Lilly stock may be issued or transferred under the Plan in the form of re-
stricted stock grants or stock unit awards, considered together.
Proposed Amendments:
• Eliminate the 3,000,000-share maximum. This limit was adopted at a time when stock grants created a
greater accounting expense to the company than stock options. With changes in accounting rules, the
expense of the different kinds of grants is comparable, and therefore the limit no longer serves its intended
purpose of minimizing the accounting cost of the Plan.
• Allow stock grants to be paid in cash to facilitate making stock grants in certain foreign countries.
Authority of Committee
The Plan is administered and interpreted by the Committee, each member of which must be a “nonemployee direc-
tor” within the meaning of Rule 16b-3 under the Securities Exchange Act of 1934 and an “outside director” within
the meaning of Section 162(m) of the Code. As to grants to employees, the Committee selects persons to receive
grants from among the eligible employees, determines the type of grants and number of shares to be awarded,
and sets the terms and conditions of the grants. The Committee may establish rules for administration of the Plan
and may delegate authority to others for plan administration, subject to limitations imposed by SEC and IRS rules
and state law.
Other Information
The Plan remains effective until April 14, 2012, unless earlier terminated by the board. The board may amend the
Plan as it deems advisable, except that shareholder approval is required for any amendment that would (i) allow
the repricing of stock options below the original option price, (ii) allow the grant of stock options at an option price
below fair market value of Lilly stock on the date of grant, (iii) increase the number of shares authorized for issu-
ance or transfer, or (iv) increase any of the various maximum limits established for stock options, performance
awards, and restricted stock.
Proposed Amendment: Extend termination date of the Plan to April 20, 2020.
The Committee may provide in the grant agreement, or by subsequent action, that the following shall occur in
the event of a change in control (as defi ned in Article 12 of the Plan), in order to preserve all of the grantee’s rights:
(i) any outstanding stock option not already vested shall become immediately exercisable; (ii) any restriction pe-
riods on restricted stock grants shall immediately lapse; and (iii) outstanding performance awards will be vested
and paid out on a prorated basis, based on the maximum award opportunity and the number of months elapsed
compared to the total number of months in the award period.
The future amounts that will be received by grantees under the Plan are not determinable. For the 2007 award
year, no stock options were granted to employees or directors, and employees received the following performance
awards, shareholder value awards (which were granted under the Plan as a form of performance award), restrict-
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ed stock grants and restricted stock units:
Group
Performance Awards (Payout)
Shareholder Value Awards
(Target) 1
Restricted Stock Grants / Units
Named Executive Offi cers
Footnote 2
Footnote 2
All Executive Offi cers as a group
(10 employees)
391,218 shares
243,754 shares
None
None
All other employees
3,577,896 shares
726,194 shares
379,176 shares
1 For 2007-2009 award period. The actual number of shares paid may vary from zero to 140 percent of target for
executive offi cers and from 40 to 140 percent of target for all other employees.
2 See page 93, narrative following Grants of Plan-Based Awards During 2007 table.
Securities Authorized for Issuance Under Equity Compensation Plans
The following table presents information as of December 31, 2007, regarding our compensation plans under which
shares of Lilly common stock have been authorized for issuance.
Plan category
Equity compensation plans approved
by security holders
Equity compensation plans not
approved by security holders 1
Total
(a) Number of securities to
be issued upon exercise of
outstanding options, warrants,
and rights
(b) Weighted-average exercise
price of outstanding options,
warrants, and rights
(c) Number of securities
remaining available for
future issuance under equity
compensation plans (excluding
securities refl ected in column (a))
71,953,815
9,195,230
81,149,045
$68.78
$75.77
$69.57
46,577,743
320,555
46,898,298
1 Represents shares in the Lilly GlobalShares Stock Plan, which permits the company to grant stock options to non-
management employees worldwide. The plan is administered by the senior vice president responsible for human
resources. The stock options are nonqualifi ed for U.S. tax purposes. The option price cannot be less than the fair
market value at the time of grant. The options shall not exceed 11 years in duration and shall be subject to vesting
schedules established by the plan administrator. There are provisions for early vesting and early termination of
the options in the event of retirement, disability, and death. In the event of stock splits or other recapitalizations,
the administrator may adjust the number of shares available for grant, the number of shares subject to outstand-
ing grants, and the exercise price of outstanding grants.
The board recommends that you vote FOR amendment of the 2002 Lilly Stock Plan.
Item 6. Shareholder Proposal Regarding International Outsourcing of Animal Research
Meredith Page, 2231 Court Ave., Memphis, Tennessee 38104, on behalf of People for the Ethical Treatment of
Animals (PeTA), 501 Front Street, Norfolk, Virginia 23510, and benefi cial owner of approximately 105 shares, has
submitted the following proposal:
Resolved, that the Board report to shareholders on the rationale for increasingly exporting the Company’s animal
experimentation to countries which have either nonexistent or substandard animal welfare regulations and little or
no enforcement. Further, the shareholders request that the report include information on the extent to which the
Company requires adherence to U.S. animal welfare standards at facilities in foreign countries.
Supporting Statement: Eli Lilly has publicly committed to an “ethical and scientifi c obligation to ensure the re-
sponsible treatment of animals used in research, to minimize the number of animals involved, and to pursue the
development of alternative test systems.”1
However, the Company is currently relocating animal research and testing to countries known for having no or
poor animal welfare standards and negligible oversight.
1 Policy statement at http://www.lilly.com/about/citizenship/key_issues/research/rd_animal.html.
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In January 2006, Business Week reported that “[i]ncreasingly, Lilly is moving its research and development,
including clinical trials, to China, India, and the former Soviet bloc.”1 Then, the August 21, 2007 issue of The Wall
Street Journal reported that Eli Lilly had entered into a partnership with a Shanghai Company known as Chi-Med by
which “Lilly will hand over preclinical research and development on several compounds to the Chinese company,”
and new agreements with Chi-Med’s Hutchison MediPharma were reported in October 2007.2
As previously reported in Forbes magazine, the rationale for outsourcing animal testing to China is that “scientists
are cheap, lab animals plentiful and pesky protesters held at bay.”3 Our Company now conducts a signifi cant propor-
tion of its research in foreign laboratories, with 20% of it based in China (its largest non-U.S.-based Research & Devel-
opment team).4 Purposely re-locating research to regions with lower animal costs, easy animal availability, and lower
welfare standards is in direct confl ict with Lilly’s stated commitment to reducing, refi ning, and replacing animal use.
As recent media reports of safety scandals and product recalls have made abundantly clear, standards for
products exported from China to the U.S. are lacking. Shareholders deserve to understand why animal testing is
being moved to foreign countries, such as China. Moreover, our Company should report on the steps that are being
taken to assure shareholders that animal testing conducted in other countries is held to at least the same animal
welfare standards as animal testing conducted in the U.S.
Accordingly, we urge shareholders to support this socially and ethically responsible resolution.
Statement in Opposition to the Proposal Regarding the International Outsourcing of Animal Research
The public policy and compliance committee of the board has reviewed the proposal submitted on PeTA’s behalf
and believes that Lilly’s current initiatives address the shareholder concerns and that additional reporting is an
unnecessary use of company resources. Lilly’s current report on our use of animals can be found in our Corporate
Citizenship Report on our website at www.lilly.com.
Lilly maintains high standards of animal care and use in all our facilities. While efforts to minimize the use
of animal testing have been underway for some time, the appropriate use of animals in research is essential to
ensure that safe and effi cacious medicines become available to patients. Furthermore, it is a requirement dictated
by regulatory agencies around the world. Lilly fully recognizes the fundamental ethical obligation to treat animals
used in research responsibly. We have both an ethical and a scientifi c interest in ensuring that standards are in
place at company and third-party facilities to ensure both appropriate animal care and valid study results. Accord-
ingly, all of the company’s sites are accredited by the Association for the Assessment and Accreditation of Labora-
tory Animal Care International (AAALAC). AAALAC accreditation is a voluntary process that includes a detailed,
comprehensive review of research animal programs such as animal care and use policies and procedures, animal
environment, housing and management, veterinary medical care, and physical plant operations.
In an increasingly competitive and global economy, Lilly regularly evaluates and develops relationships with
entities that can assist in meeting our productivity and core mission objectives; this includes select laboratory ani-
mal research and animal supply companies. Relocating research to regions with lower animal costs does not af-
fect Lilly’s stated commitment to reducing, refi ning, and replacing animal use. Regardless of local variations, Lilly
seeks to do business only with those companies that share our commitment to animal welfare. We also require the
companies that we work with to comply with applicable local laws and treat animals in a humane manner.
Lilly has been adding provisions to our contracts with third parties who do research on our behalf or supply
laboratory animals to our facilities, requiring these parties to comply with the principles of Lilly’s Animal Care and
Use Policy, and we will periodically assess their adherence to these expectations. We recently revised our Animal
Care and Use policy to refl ect this requirement.
Lilly believes that international research efforts may facilitate the harmonization of global animal welfare
standards. To this end, Lilly actively shares its views on the importance of animal welfare in the research context
with international regulatory bodies and research scientists in other countries around the world, including China.
Leading Lilly research scientists seek opportunities to present data on the care and use of laboratory animals at
international scientifi c forums and to government offi cials. Lilly actively encourages animal research and ani-
mal supply companies, both inside and outside the United States, to obtain and maintain AAALAC accreditation.
Through active engagement, Lilly is helping to raise the standards of animal care and use in countries that have not
had such standards or enforced them.
The board recommends that you vote AGAINST this proposal.
1 “Lilly’s Labs Go Global”; Business Week (Jan. 30, 2006)
2 http://www.drugresearcher.com/news/ng.asp?n=80470&m=1DRGO10&c=iubqfdmlvoteibj,
3 “Comparative Advantage”; Forbes, p. 76 Vol. 178 No. 10 (Nov. 13, 2006)
4 See footnote 3.
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Item 7. Shareholder Proposal Regarding Allowing Shareholders to Amend the Company’s Bylaws
California Public Employees’ Retirement System (CalPERS), P.O. Box 942707, Sacramento, California 94229-2707,
benefi cial owner of approximately 4.7 million shares, has submitted the following proposal:
RESOLVED, that the shareowners of Eli Lilly & Company (“Company”) urge the Company to take all steps neces-
sary, in compliance with applicable law, to allow its shareowners to amend the Company’s bylaws by a majority
vote. Currently, the Company does not allow shareowners to amend the Company’s bylaws.
Supporting Statement: The most important shareowner power is the power to vote. In most cases, in addition
to having the power to vote to elect directors, shareowners are able to vote to amend a company’s bylaws. Ap-
proximately 95% of companies in the S&P 500 and the Russell 1000 allow shareowners to amend the bylaws. The
Company is one of the very few companies in the S&P 500 that does not give shareowners this power.
Bylaws typically contain corporate governance provisions of the utmost importance to shareowners, e.g., the
ability to call a special meeting, the ability to remove directors, anti-takeover provisions, director election rules,
among other provisions. Without a formal mechanism to impact a company’s governance through bylaw amend-
ments, the shareowners of a company are disenfranchised. In fact, limiting shareowner ability to amend the by-
laws has been found to be one of six entrenching mechanisms that are negatively correlated with company perfor-
mance. See “What Matters in Corporate Governance?” Lucian Bebchuk, Alma Cohen & Allen Ferrell, Harvard Law
School, Discussion Paper No. 491 (09/2004, revised 03/2005).
This proposal asks for a majority vote standard to amend the bylaws of the Company since a supermajority
vote can be almost impossible to obtain in light of abstentions and broker nonvotes. For example, a proposal to de-
classify the board of directors fi led at Goodyear Tire & Rubber Company failed to pass by a majority of shares out-
standing even though approximately 90 percent of votes cast were in favor of the proposal. While it is often stated
by corporations that the purpose of supermajority requirements is to provide corporations the ability to protect
minority shareowners, supermajority requirements are most often used, in CalPERS’ opinion, to block initiatives
opposed by management and the board of directors but supported by most shareowners. At the Sara Lee Corpora-
tion, approximately 81% of shareowners agreed when it passed a proposal identical to this proposal.
This is why CalPERS is sponsoring this proposal that, if passed and implemented, would make the Company
more accountable to shareowners by allowing shareowners to amend the bylaws by majority vote. As a trust fund
with more than 1.4 million participants, and as the owner of approximately 4.7 million shares of the Company’s
common stock, CalPERS believes that corporate governance procedures and practices, and the level of account-
ability they impose, are closely related to fi nancial performance. CalPERS also believes that shareowners are
willing to pay a premium for shares of corporations that have excellent corporate governance. If the Company were
to take steps to implement this proposal, it would be a strong statement that this Company is committed to good
corporate governance and its long-term fi nancial performance.
Please vote FOR this proposal.
Statement in Opposition to the Proposal Regarding Amending the Company’s Bylaws
The board of directors believes that this proposal is not in the best long-term interests of the shareholders and
recommends that you vote against it.
The company’s bylaws establish a number of fundamental corporate governance operating principles, includ-
ing rules for meetings of directors and shareholders, election and duties of directors and offi cers, authority to
approve transactions, and procedures for stock issuance. Like many other Indiana corporations, Lilly has adopted
the default provision under Indiana law, which states that unless the articles of incorporation provide otherwise,
the bylaws may be amended only by the directors.
The board of directors has fi duciary obligations to the company and all its shareholders, including large insti-
tutions, small institutions, and individual investors. The board believes that allowing the bylaws to be amended by
a majority shareholder vote would expose the shareholders to the risk that a few large shareholders who wish to
advance their own special interests—and who have no duties to the other shareholders—could adopt changes in
these operating principles that could be detrimental to minority shareholders. Under the majority vote standard
endorsed by the proponent (requiring only a majority of shares voted at the meeting), shareholders holding signifi -
cantly less than half of the outstanding shares could adopt bylaw amendments to further their own special inter-
ests. The board, on the other hand, has fi duciary duties to consider and balance the interests of all shareholders
when considering bylaw provisions, and is better positioned to ensure that any bylaw amendments are prudent and
are designed to protect and maximize long-term value for all shareholders.
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The proponent suggests this proposal is necessary to foster good governance principles at the company and
make the directors more accountable to the shareholders. On the contrary, the board has been for many years, and
intends to remain, a leader in corporate governance. The company has adopted comprehensive corporate gover-
nance principles, consistent with best practices, that ensure the company remains fully transparent and account-
able to shareholders. Further, the board is taking three major steps to demonstrate its continuing commitment to
good corporate governance and accountability to shareholders:
• In this proxy statement, the board is seeking shareholder approval to eliminate the classifi ed board (see Item 3).
• The board is also seeking shareholder approval to adopt a majority voting standard for uncontested director
elections (see Item 4).
• The board has determined that it will not renew the company’s shareholder rights plan when it expires in July 2008.
The proponent also suggests that adopting this proposal will enhance company performance because compa-
nies with good corporate governance are more highly valued. We certainly agree that strong corporate governance
practices benefi t shareholders, but we do not believe that this particular proposal will improve the company’s
corporate governance or lead to better performance. In fact, a 2004 study by Lawrence D. Brown and Marcus L.
Caylor of Georgia State University 1 found that companies that permit shareholders to amend the bylaws performed
no better or worse than those who reserve that power to the directors. This is consistent with our view that adopt-
ing this proposal would not enhance our already strong corporate governance practices and instead would expose
minority shareholders to actions detrimental to their best interests.
The board recommends that you vote AGAINST this proposal.
Item 8. Shareholder Proposal Regarding Adopting a Simple Majority Vote Standard
William Steiner, 112 Abbottsford Gate, Piermont, New York 10968, benefi cial owner of approximately 1,700 shares,
has submitted the following proposal:
8—Adopt Simple Majority Vote
RESOLVED, Shareowners urge our company to take all steps necessary, in compliance with applicable law, to fully
adopt simple majority vote requirements in our Charter and Bylaws. This includes special solicitations.
This shareholder proposal topic won our 62%-support at our 2007 annual meeting. Simple majority vote also
won an impressive 72% yes-vote average at 24 major companies in 2007. The Council of Institutional Investors
www.cii.org recommends adoption of simple majority vote and the adoption of shareholder proposals upon receiv-
ing their fi rst majority vote.
Hopefully our management is not headed for the same category as FirstEnergy (FE), a serial ignorer of major-
ity shareholder votes. As a result each FirstEnergy director candidate received 27% to 39% in opposing votes at the
2007 FirstEnergy annual meeting.
Currently a 1%-minority can frustrate the will of our 79%-shareholder majority under our 80% supermajor-
ity provision. Also our supermajority vote requirements can be almost impossible to obtain when one considers
abstentions and broker nonvotes. For example, a Goodyear (GT) proposal failed to pass even though 90% of votes
cast were yes-votes.
Furthermore, our management said in its 2007 annual proxy that a supermajority provision is by no means
insurmountable. Then our management promptly failed to obtain the 80% supermajority vote required to pass its
own proposal for annual election of each director.
Mr. Fisher, Chairman of our Governance Committee did not authorize a special solicitation fi ling in order to
make a good effort to obtain the 80% vote. Because of this management failure, shareholders are now encouraged
to submit an annual election shareholder proposal so that it will be adopted by our company.
The merits of adopting this proposal should also be considered in the context of our company’s overall corpo-
rate governance structure and individual director performance. For instance in 2007 the following structure and
performance issues were reported (and certain concerns are noted):
• The Corporate Library http://www.thecorporatelibrary.com, an independent investment research fi rm, rated our
company:
“D” in governance.
“High Governance Risk Assessment.”
“Very High Concern” in Takeover Defenses.
1 Brown, L.D. and M.L. Caylor. 2004. The Correlation between Corporate Governance and Company Performance. Institutional Shareholder Services
White Paper.
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“High Concern” in Executive Pay.
• No shareholder right to:
1) Cumulative voting.
2) To act by written consent.
3) To call a special meeting.
• Five of our directors were potentially confl icted:
Mr. Bischoff
Mr. Prendergast
Mr. Feldstein
Mr. Fyrwald
Mr. Gilman
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• Three directors were designated “Accelerated Vesting” directors by The Corporate Library—due to a director’s
involvement with a board that accelerated stock option vesting in order to avoid recognizing the corresponding
expense:
Mr. Cook
Mr. Feldstein
Ms. Marram
• Poison pill with a 15% trigger.
• We had no independent Chairman—Independent oversight concern.
• Plus our lead director, Ms. Horn had 20-year tenure—Independence concern.
The above concerns shows there is room for improvement and reinforces the reason to take one step forward
now to encourage our board to respond positively to our 62%-support for this topic:
Adopt Simple Majority Vote—
Yes on 8
Statement in Opposition to the Proposal Regarding Adopting a Simple Majority Vote Standard
This proposal, which does not pertain to the election of directors, calls for the elimination of provisions in the
company’s articles of incorporation that require more than a simple majority vote for certain actions to be ap-
proved. The board of directors believes that this would not be in the best long-term interest of the shareholders
and recommends that you vote against it.
Most proposals submitted to a vote of the company’s shareholders can already be adopted by a simple ma-
jority vote. However, in 1985 the company’s shareholders voted to increase the approval requirement for a few
fundamental corporate actions. These actions, which require the approval of at least 80 percent of the outstanding
shares of stock entitled to vote, relate to:
• removal of directors
• the amendment of the articles of incorporation’s provisions relating to the terms of offi ce and removal of
directors 1
• merger, consolidation, recapitalization, or certain other business combinations involving the company that are
not approved by the board of directors
• the amendment of the articles of incorporation’s provisions relating to such mergers and other business
combinations.
The board believes that in adopting these supermajority voting provisions, shareholders intended to preserve
and maximize the value of Lilly stock for all shareholders by protecting against short-term, self-interested actions
by one or a few large shareholders. These provisions help ensure that important corporate governance rules are
not changed without the clear consensus of a substantial majority of stockholders that such change is prudent and
in the best interests of the company.
The board has a fi duciary duty under the law to act in a manner it believes to be in the best interests of the
company and its shareholders. In the event of an unfriendly or unsolicited bid from one or a few large shareholders
to take over or restructure the company, these supermajority voting provisions encourage bidders to negotiate with
the board on behalf of all shareholders. In addition, they allow the board time and bargaining leverage to consider
1 Under Item 3, the board is recommending that the shareholders approve amendments to these provisions that would establish annual election of direc-
tors.
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alternative proposals that maximize the value of the company for all shareholders, including large institutional
investors as well as smaller institutions and individual shareholders.
The board believes that these supermajority voting provisions protect all shareholders by making it more
diffi cult for one or a few large shareholders to replace important corporate governance rules of the company to
further a special interest, or to take control of the company, without negotiating with the board to assure that the
best results are achieved for all shareholders.
The board recommends that you vote AGAINST this proposal.
Item 9. Shareholder Proposal Regarding Reporting on the Company’s Political Contributions
The American Federation of Labor and Congress of Industrial Organizations (AFL-CIO), 815 Sixteenth Street, N.W.,
Washington, D.C. 20006, benefi cial owner of approximately 700 shares, has submitted the following proposal:
Resolved, that the shareholders of Eli Lilly and Company (the “Company”) hereby request that the Company pro-
vide a report, updated semi-annually, disclosing the Company’s:
1. Policies and procedures for political contributions and expenditures (both direct and indirect) made with
corporate funds.
2. Monetary and non-monetary political contributions and expenditures not deductible under Section 162 (e)(1)(B)
of the Internal Revenue Code, including but not limited to contributions to or expenditures on behalf of political
candidates, political parties, political committees and other political entities organized and operating under
26 USC Sec. 527 of the Internal Revenue Code and any portion of any dues or similar payments made to any
tax exempt organization that is used for an expenditure or contribution if made directly by the corporation
would not be deductible under Section 162 (e)(1)(B) of the Internal Revenue Code. The report shall include the
following:
a. An accounting of the Company’s funds that are used for political contributions or expenditures as
described above;
b. Identifi cation of the person or persons in the Company who participated in making the decisions to make
the political contribution or expenditure; and
c. The internal guidelines or policies, if any, governing the Company’s political contributions and expenditures.
The report shall be presented to the board of directors’ audit committee or other relevant oversight commit-
tee and posted on the Company’s website to reduce costs to shareholders.
Supporting Statement: As long-term shareholders, we support policies that apply transparency and accountabil-
ity to corporate spending on political activities. Absent a system of accountability, we believe that company assets
can be used for political objectives that are not shared by and may be inimical to the interests of the Company and
its shareholders. We are concerned that there is currently no single source of information that provides all of the
information sought by this resolution.
Data from the Federal Election Commission and the Internal Revenue Service provides an incomplete picture of
our Company’s political donations. Although corporate contributions to political parties are prohibited at the federal
level, companies can contribute to independent political committees, or 527s. In addition, payments can be made to
trade associations, and the portion of those payments used for political activities do not have to be disclosed.
Trade associations engage in political activity that may support or confl ict with our Company’s positions on
important issues like universal access to healthcare, biomedical research and women’s health choices.
The recently enacted Honest Leadership and Open Government Act requires greater disclosure of trade as-
sociation political and lobbying activity including the reporting of all contributions bundled by a trade association’s
political action committee and the listing of all companies who contribute more than $5,000 in any quarterly period
in support of a trade association’s lobbying activity. Company disclosure will help assure that trade associations
are meeting their legal obligation in reporting political and lobbying activity and that those activities are consistent
with the interests of our Company as a member of a trade association.
Statement in Opposition to the Proposal Regarding Reports on the Company’s Political Contributions
The public policy and compliance committee of the board has reviewed this proposal and recommends a vote
against it as we currently publish most of the information requested by the shareholder. The additional reporting
requirements are unnecessary, as the information requested is publicly available and this reporting would place
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an undue administrative burden on the company.
Beginning in the fi rst quarter of 2005, the company has published the following information on our website
(www.lilly.com) for both direct company contributions and employee political action committee (PAC) contributions
to support candidates for political offi ce, political parties, offi cials, or committees in the United States:
• policies and procedures for company and PAC contributions
• contributions to candidates, including information about the candidate's offi ce (for example, state, local, or
federal; House or Senate), party affi liation, state, and district
• contributions to political organizations and Section 527 organizations reported by state.
This information is updated annually. In addition to the information available on our website, detailed corporate
contributions, PAC contribution data, and the company’s direct lobbying expenses are available to the public on the
Federal Election Commission website (http://www.fec.gov/disclosure.shtml) and through individual states’ agen-
cies.
One way we participate in the political process is by maintaining memberships in trade associations specifi c
to business and pharmaceutical industry interests, such as PhRMA (Pharmaceutical Research and Manufactur-
ers Association), BIO (Biotechnology Association), Healthcare Leadership Conference, and Business Roundtable.
In our 2007 Report of Political Financial Support, to be published by April 2008, we will report the names of the
major U.S. trade associations to which Lilly belongs, where our annual membership dues exceed $50,000; we will
also note where we have a board seat. These tax-exempt organizations are all required to disclose their lobbying
expenditures under the Lobbying Act of 1995; they report their lobbying expenditures to the United States Senate
(http://www.senate.gov/pagelayout/legislative/g_three_sections_with_teasers/lobbyingdisc.htm). As we do not
control what portion of the organization’s budget is spent on lobbying, it is the fact of company membership and
support for the trade association, and the trade association’s total lobbying expenditure, that reveals the most
about Lilly's political activities.
The board recommends that you vote AGAINST this proposal.
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Other Matters
Section 16(a) Benefi cial Ownership Reporting Compliance
Under Securities and Exchange Commission rules, our directors and executive offi cers are required to fi le with the
Securities and Exchange Commission reports of holdings and changes in benefi cial ownership of company stock.
We have reviewed copies of reports provided to the company, as well as other records and information. Based on
that review, we concluded that all reports were timely fi led except that, due to administrative error, Mr. Rice fi led
one late report in connection with the receipt of performance award shares by his wife, a former Lilly employee.
Upon discovery, this matter was promptly reported.
Certain Legal Matters
In April 2007, the company received demands from two shareholders that the board of directors cause the company
to take legal action against current and former directors and others for allegedly causing damage to the company
with respect to the allegedly improper marketing of Evista, Prozac, and Zyprexa. We received a similar demand
in September related only to Zyprexa. In accordance with procedures established under the Indiana Business
Corporation Law (Ind. Code §23-1-32), the board has appointed a committee of independent persons to consider
the demands and determine what action, if any, the company should take in response. In January 2008, two of the
three shareholders who had submitted the demands fi led a derivative suit in the United States District Court for
the Southern District of Indiana, nominally on behalf of the company, against various current and former directors
and offi cers. The suit alleges that the board of directors constructively denied the shareholders’ prior demands by
failing to take action on the demands suffi ciently promptly. Each of the current directors, other than Mr. Eskew, is
named in the suit. We believe this suit is without merit and are prepared to defend against it vigorously.
Other Information Regarding the Company’s Proxy Solicitation
We will pay all expenses in connection with our solicitation of proxies. We will pay brokers, nominees, fi ducia-
ries, or other custodians their reasonable expenses for sending proxy material to and obtaining instructions from
persons for whom they hold stock of the company. We expect to solicit proxies primarily by mail, but directors,
offi cers, and other employees of the company may also solicit in person or by telephone, fax, or electronic mail. We
have retained Georgeson Shareholder Communications Inc. to assist in the distribution and solicitation of proxies.
Georgeson may solicit proxies by personal interview, telephone, fax, mail, and electronic mail. We expect that the
fee for those services will not exceed $17,500 plus reimbursement of customary out-of-pocket expenses.
By order of the board of directors,
James B. Lootens
Secretary
March 10, 2008
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Appendix A
Proposed Amendments to the Company’s Articles of Incorporation
Proposed changes to the company’s articles of incorporation are shown below related to Items 3 and 4, Items of
Business to Be Acted Upon at the Meeting. The proposed changes to Article 9 relate to Item 3. The addition of a new
Article 15 relates to Item 4. Additions are indicated by underlining and deletions are indicated by strike-outs.
. . . . .
9. The following provisions are inserted for the management of the business and for the conduct of the affairs of
the Corporation, and it is expressly provided that the same are intended to be in furtherance and not in limitation or
exclusion of the powers conferred by statute:
(a) The number of directors of the Corporation, exclusive of directors who may be elected by the holders of any
one or more series of Preferred Stock pursuant to Article 7(b) (the “Preferred Stock Directors”), shall not be
less than nine, the exact number to be fi xed from time to time solely by resolution of the Board of Directors,
acting by not less than a majority of the directors then in offi ce.
(b) The Prior to the 2009 annual meeting of shareholders, the Board of Directors (exclusive of Preferred Stock
Directors) shall be is divided into three classes, with the term of offi ce of one class expiring each year. At Com-
mencing with the annual meeting of shareholders in 1985, fi ve 2009, each class of directors of the fi rst class
whose term shall then or thereafter expire shall be elected to hold offi ce for a one-year term expiring at the
1986 next annual meeting of, fi ve directors of the second class shall be elected to hold offi ce for a term expir-
ing at the 1987 annual meeting, and six directors of the third class shall be elected to hold offi ce for a term
expiring at shareholders. In the case of any vacancy on the Board of Directors occurring after the 1988 2008
annual meeting. Commencing with the annual meeting of shareholders in 1986, each class of directors whose
term shall then expire shall be elected to hold offi ce for a three year term. In the case of any vacancy on the
Board of Directors, including a vacancy created by an increase in the number of directors, the vacancy shall be
fi lled by election of the Board of Directors with the director so elected to serve for the remainder of the term of
the director being replaced or, in the case of an additional director, for the remainder of the term of the class
to which the director has been assigned. until the next annual meeting of shareholders. All directors shall
continue in offi ce until the election and qualifi cation of their respective successors in offi ce. When the number
of directors is changed, any newly created directorships or any decrease in directorships shall be so assigned
among the classes by a majority of the directors then in offi ce, though less than a quorum, as to make all
classes as nearly equal in number as possible. No decrease in the number of directors shall have the effect of
shortening the term of any incumbent director. Election of directors need not be by written ballot unless the
By-laws so provide.
(c) Any director or directors (exclusive of Preferred Stock Directors) may be removed from offi ce at any time,
but only for cause and only by the affi rmative vote of at least 80% of the votes entitled to be cast by holders of
all the outstanding shares of Voting Stock (as defi ned in Article 13 hereof), voting together as a single class.
(d) Notwithstanding any other provision of these Amended Articles of Incorporation or of law which might
otherwise permit a lesser vote or no vote, but in addition to any affi rmative vote of the holders of any particu-
lar class of Voting Stock required by law or these Amended Articles of Incorporation, the affi rmative vote of
at least 80% of the votes entitled to be cast by holders of all the outstanding shares of Voting Stock, voting
together as a single class, shall be required to alter, amend or repeal this Article 9.
. . . . .
15. Subject to the rights of the holders of preferred stock to elect any directors voting separately as a class or
series, at each annual meeting of shareholders, the directors to be elected at the meeting shall be chosen by the
majority of the votes cast by the holders of shares entitled to vote in the election at the meeting, provided a quorum
is present; provided, however, that if the number of nominees exceeds the number of directors to be elected, then
directors shall be elected by the vote of a plurality of the votes cast by the holders of shares entitled to vote, pro-
vided a quorum is present. For purposes of this Article 15, a “majority of votes cast” shall mean that the number of
votes cast “for” a director’s election exceeds the number of votes cast “against” that director’s election.
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Appendix B
Proposed Amendments to the 2002 Lilly Stock Plan
Proposed changes to the company’s 2002 Lilly Stock Plan are shown below related to Item 5, Items of Business to
Be Acted Upon at the Meeting. Additions are indicated by underlining and deletions are indicated by strike-outs.
2002
LILLY STOCK PLAN
As amended through October 18, 2004April 21, 2008
The 2002 Lilly Stock Plan (“2002 Plan”) authorizes the Board of Directors of Eli Lilly and Company (“Board”) and
the Compensation Committee of the Board, as applicable, to provide offi cers and other employees of Eli Lilly and
Company and its subsidiaries and nonemployee directors of Eli Lilly and Company (“Nonemployee Directors”)
with certain rights to acquire shares of Eli Lilly and Company common stock (“Lilly Stock”). The Company believes
that this incentive program will benefi t the Company’s shareholders by allowing the Company to attract, motivate,
and retain employees and directors and by providing those employees and directors stock-based incentives to
strengthen the alignment of interests between those persons and the shareholders. For purposes of the 2002 Plan,
the term “Company” shall mean Eli Lilly and Company and its subsidiaries, unless the context requires otherwise.
1. Administration.
(a) Grants to Eligible Employees. With respect to Grants to Eligible Employees (as those terms are defi ned in
Sections 2 and 3(a), respectively), the 2002 Plan shall be administered and interpreted by the Compensation
Committee of the Board consisting of not less than two independent directors appointed by the Board from
among its members. A person may serve on the Compensation Committee for purposes of administration and
interpretation of the 2002 Plan only if he or she (i) is a “Non-employee Director” for purposes of Rule 16b-3
under the Securities Exchange Act of 1934, as amended (the “1934 Act”), and (ii) satisfi es the requirements of
an “outside director” for purposes of Section 162(m) of the Internal Revenue Code of 1986, as amended (the
“Code”), and (iii) satisfi es the New York Stock Exchange rules for independence. The Compensation Committee
may, subject to the provisions of the 2002 Plan, from time to time establish such rules and regulations and
delegate such authority to administer the 2002 Plan as it deems appropriate for the proper administration of
the Plan, except that no such delegation shall be made in the case of awards intended to be qualifi ed under
Rule 16b-3 of the 1934 Act or Section 162(m) of the Code. The decisions of the Compensation Committee or its
authorized designees (the “Committee”) shall be made in its sole discretion and shall be fi nal, conclusive, and
binding with respect to the interpretation and administration of the 2002 Plan and any Grant made under it.
(b) Grants to Nonemployee Directors. With respect to Stock Option Grants made to Nonemployee Directors pursuant
to Section 8, the Board shall serve to administer and interpret the 2002 Plan and any such Grants, and all
duties, powers and authority given to the Committee in subsection (a) above or elsewhere in the 2002 Plan in
connection with Grants to Eligible Employees shall be deemed to be given to the Board in its sole discretion in
connection with Stock Option Grants to Nonemployee Directors.
2. Grants.
Incentives under the 2002 Plan shall consist of incentive stock options or other forms of tax-qualifi ed stock options
under the Code, nonqualifi ed stock options, performance awards, stock appreciation rights, stock unit awards,
and restricted stock grants (collectively, “Grants”). The Committee shall approve the form and provisions of each
Grant to Eligible Employees and the Board shall approve the form and provisions of each Stock Option Grant to
Nonemployee Directors. All Grants shall be subject to the terms and conditions set out herein and to such other
terms and conditions consistent with the 2002 Plan as the Committee or Board, as applicable, deems appropriate.
Grants under a particular section of the 2002 Plan need not be uniform and Grants under two or more sections
may be combined in one instrument. The Committee shall determine the fair market value of Lilly Stock for pur-
poses of the 2002 Plan.
3. Eligibility for Grants.
(a) Grants to Eligible Employees. Grants may be made to any employee of the Company, including a person who is
also a member of the Board of Directors (“Eligible Employee”). The Committee shall select the persons to receive
Grants (“Grantees”) from among the Eligible Employees and determine the number of shares subject to any
particular Grant.
(b) Grants to Nonemployee Directors. Grants of Stock Options may be made to any member of the Board who is not
an employee of the Company (a “Nonemployee Director”). The Board shall select the persons who will receive
Stock Options Grants (“Grantees”) from among the Nonemployee Directors and determine the number of
shares subject to any particular Stock Option Grant.
4. Shares Available for Grant.
(a) Shares Subject to Issuance or Transfer. Subject to adjustment as provided in Section 4(b), the aggregate number
of shares of Lilly Stock that may be issued or transferred under the 2002 Plan shall be the sum of the following
amounts:
(i) 80,000,000 119,000,000 shares;
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(ii) Any shares of Lilly Stock subject to an award hereunder or under the 1989, 1994 or 1998 Lilly Stock
Plans (the “Prior Shareholder-Approved Plans”) which, after the effective date of the 2002 Plan,:
a. are not purchased or awarded under a Stock Option or Performance Award due to termination,
lapse, or forfeiture, or which are forfeited under a Restricted Stock Grant; are not issued or
transferred in connection with a Stock Option, Stock Appreciation Right or Stock Unit Award due to
termination, lapse, surrender or forfeiture;
b. are not issued or transferred in connection with the payment of a Performance Award due to ter-
mination, lapse, surrender, forfeiture, failure to achieve Performance Goals, or payment in cash in
lieu of shares pursuant to Section 6(c); or
c. are forfeited under a Restricted Stock Grant.
(iii) Upon the termination or expiration of the 1998 Lilly Stock Plan, any shares of Lilly Stock that remained
available for grant under that plan at the time of termination or expiration; and
(iv) The number of shares of Lilly Stock exchanged by a Grantee as full or partial payment to the Company
of the exercise price of a Stock Option that was granted hereunder or under a Prior Shareholder-Ap-
proved Plan or withheld for taxes under Sections 5(e), 7(c), 9(e) or 10(c).
The shares may be authorized but unissued shares or treasury shares.
(b) Adjustment Provisions. If any subdivision or combination of shares of Lilly Stock or any stock dividend,
reorganization, recapitalization, or consolidation or merger with Eli Lilly and Company as the surviving
corporation occurs, or if additional shares or new or different shares or other securities of the Company or any
other issuer are distributed with respect to the shares of Lilly Stock through a spin-off or other extraordinary
distribution, the Committee shall make such adjustments as it determines appropriate in the number of shares
of Lilly Stock that may be issued or transferred in the future under Sections 4(a), 5(f) and (g), 6(f), 7(e), and 9(d),
and 10(c). The Committee shall also adjust as it determines appropriate the number of shares and Option Price
or base price as applicable in outstanding Grants made before the event.
5. Stock Option Grants to Eligible Employees.
The Committee may grant to Eligible Employees options qualifying as incentive stock options under the Code (“In-
centive Stock Options”), other forms of tax-favored stock options under the Code, and nonqualifi ed stock options
(collectively, “Stock Options”). The Committee shall determine the terms and conditions applicable to Stock Options
granted to Eligible Employees consistent with the following:
(a) Option Price. The Committee shall determine the price or prices at which Lilly Stock may be purchased by the
Grantee under a Stock Option (“Option Price”) which shall be not less than the fair market value of Lilly Stock
on the date the Stock Option is granted (the “Grant Date”). In the Committee’s discretion, the Grant Date of a
Stock Option may be established as the date on which Committee action approving the Stock Option is taken or
any later date specifi ed by the Committee. Once established, the Option Price may not be reduced except in the
case of adjustments under Section 4(b).
(b) Option Exercise Period. The Committee shall determine the option exercise period of each Stock Option. The
period shall not exceed ten years from the Grant Date in the case of an Incentive Stock Option, and eleven years
in the case of any other Stock Option.
(c) Exercise of Option. A Stock Option will be deemed exercised by a Grantee upon delivery of (i) a notice of exercise
to the Company or its representative as designated by the Committee, and (ii) accompanying payment of the
Option Price if the Stock Option requires such payment at the time of exercise. The notice of exercise, once
delivered, shall be irrevocable.
(d) Satisfaction of Option Price. A Stock Option may require payment of the Option Price upon exercise or may specify
a period not to exceed 30 days following exercise within which payment must be made (“Payment Period”).
The Grantee shall pay or cause to be paid the Option Price in cash, or with the Committee’s permission, by
delivering (or providing adequate evidence of ownership of) shares of Lilly Stock already owned by the Grantee
and having a fair market value on the date of exercise equal to the Option Price, or a combination of cash and
such shares. If the Grantee fails to pay the Option Price within the Payment Period, the Committee shall have
the right to take whatever action it deems appropriate, including voiding the option exercise or voiding that part
of the Stock Option for which payment was not timely received. The Company shall not deliver shares of Lilly
Stock upon exercise of a Stock Option until the Option Price and any required withholding tax are fully paid.
(e) Share Withholding. With respect to any Stock Option, the Committee may, in its discretion and subject to such
rules as the Committee may adopt, permit or require the Grantee to satisfy, in whole or in part, any withholding
tax obligation which may arise in connection with the exercise of the nonqualifi ed option by having the Company
withhold shares of Lilly Stock having a fair market value equal to the amount of the withholding tax.
(f) Limits on Individual Grants. No individual Grantee may be granted Stock Options or Stock Appreciation Rights,
considered together, under the 2002 Plan for more than 2,500,000 3,500,000 shares of Lilly Stock in any period
of three consecutive calendar years.
(g) Limits on Incentive Stock Options. The aggregate fair market value of the stock covered by Incentive Stock
Options granted under the 2002 Plan or any other stock option plan of the Company or any subsidiary or
parent of the Company that become exercisable for the fi rst time by any employee in any calendar year shall
not exceed $100,000 (or such other limit as may be established by the Code). The aggregate fair market value
for this purpose will be determined at the Grant Date. An Incentive Stock Option shall not be granted to any
Eligible Employee who, on the Grant Date, owns stock possessing more than 10 percent of the total combined
voting power of all classes of stock of the Company or any subsidiary or parent of the Company. Not more than
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360,000,000 shares of Lilly Stock may be issued or transferred under the 2002 Plan in the form of Incentive
Stock Options.
6. Performance Awards to Eligible Employees.
The Committee may grant to Eligible Employees Performance Awards, which shall be denominated at the time
of grant either in shares of Lilly Stock (“Stock Performance Awards”) or in dollar amounts (“Dollar Performance
Awards”). Payment under a Stock Performance Award or a Dollar Performance Award shall be made, at the dis-
cretion of the Committee, in shares of Lilly Stock (“Performance Shares”), or in cash or in any combination thereof,
if the fi nancial or market performance of the Company or any subsidiary, division, or other unit of the Company
(“Business Unit”) selected by the Committee meets certain fi nancial goals established by the Committee for the
Award Period. The following provisions are applicable to Performance Awards:
(a) Award Period. The Committee shall determine and include in the Grant the period of time (which shall be four
or more consecutive fi scal quarters) for which a Performance Award is made (“Award Period”). Grants of
Performance Awards need not be uniform with respect to the length of the Award Period. Award Periods for
different Grants may overlap. A Performance Award may not be granted for a given Award Period after one
half (1/2) or more of such period has elapsed, or in the case of an Award intended to be qualifi ed under Section
162(m) of the Code, after 90 days or more of such period has elapsed.
(b) Performance Goals and Payment. Before a Grant is made, the Committee shall establish objectives
(“Performance Goals”) that must be met by the Business Unit during the Award Period as a condition to
payment being made under the Performance Award. The Performance Goals, which must be set out in the
Grant, are limited to earnings per share; divisional income; net income; return on equity; sales; divisional sales;
economic value added (EVA); market value added (MVA); any of the foregoing before the effect of acquisitions,
divestitures, accounting changes, and restructuring and special charges, and other unusual gains or losses
(determined according to criteria established by the Committee at or within 90 days after the time of grant);
total shareholder return; or stock price goals. The Committee shall also set forth in the Grant the number of
Performance Shares or the amount of payment to be made under a Performance Award if the Performance
Goals are met or exceeded, including the fi xing of a maximum payment (subject to Section 6(f)).
(c) Computation of Payment. After an Award Period, the fi nancial performance of the Business Unit during the
period shall be measured against the Performance Goals. If the minimum Performance Goals are not met, no
payment shall be made under a Performance Award. If the minimum Performance Goals are met or exceeded,
p Prior to payment the Committee shall certify that fact in writing as to the performance achieved against
the Performance Goals and certify the number of Performance Shares, if any, or the amount of payment, if
any, to be made under a Performance Award in accordance with the grant for each Grantee. The Committee,
in its sole discretion, may elect to pay part or all of the Performance Award in cash in lieu of issuing or
transferring Performance Shares. The cash payment shall be based on the fair market value of Lilly Stock on
the date of payment (subject to Section 6(f)). The Company shall promptly notify each Grantee of the number of
Performance Shares and the amount of cash, if any, he or she is to receive.
(d) Revisions for Signifi cant Events. At any time before payment is made, the Committee may revise the Performance
Goals and the computation of payment if unusual events occur during an Award Period which have a substantial
effect on the Performance Goals and which in the judgment of the Committee make the application of
the Performance Goals unfair unless a revision is made; provided, however, that no such revision shall be
permissible with respect to a Performance Award intended to qualify for exemption under Section 162(m) of the
Code, except that the Committee (i) may provide in the terms of any such Performance Award that revisions to
the Performance Goals shall be made on a non-discretionary basis upon the occurrence of one or more specifi c
objective events, the occurrence of which are substantially uncertain at the time of grant, and (ii) may in its
discretion make a revision with respect to such Performance Award that results in a lesser payment than would
have occurred without the revision or in no payment at all.
(e) Requirement of Employment. To be entitled to receive payment under a Performance Award, a Grantee must
remain in the employment of the Company to the end of the Award Period, except that the Committee may
provide for partial or complete exceptions to this requirement as it deems equitable in its sole discretion,
consistent with maintaining the exemption under Section 162(m) of the Code. The Committee may impose
additional conditions on the Grantee’s entitlement to receive payment under a Performance Award.
(f) Maximum Payments. (i) No individual may receive Performance Award payments in respect of Stock Performance
Awards in excess of 100600,000 shares of Lilly Stock in any calendar year or payments in respect of Dollar
Performance Awards in excess of $8,000,000 in any calendar year. For purposes of determining the maximum
payment under this subsection, payment in cash of all or part of a Stock Performance Award will be deemed an
issuance of the number of shares with respect to which such cash payment is made. No individual may receive
both a Stock Performance Award and a Dollar Performance Award for the same Award Period.
(ii) Not more than 18,000,000 shares of Lilly Stock may be issued or transferred under the 2002 Plan in the
form of Performance Awards.
7. Restricted Stock Grants to Eligible Employees.
The Committee may issue or transfer shares of Lilly Stock to an Eligible Employee under a Restricted Stock Grant.
Upon the issuance or transfer, the Grantee shall be entitled to vote the shares and to receive any dividends paid.
The following provisions are applicable to Restricted Stock Grants:
(a) Requirement of Employment. If the Grantee’s employment terminates during the period designated in the Grant
as the “Restriction Period,” the Restricted Stock Grant terminates and the shares immediately revert to the
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Company. However, the Committee may provide for partial or complete exceptions to this requirement as it
deems equitable.
(b) Restrictions on Transfer. During the Restriction Period, a Grantee may not sell, assign, transfer, pledge,
or otherwise dispose of the shares of Lilly Stock except to a Successor Grantee under Section 13(a). Each
certifi cate for shares issued or transferred under a Restricted Stock Grant shall be held in escrow by the
Company until the expiration of the Restriction Period.
(c) Withholding Tax. Before delivering the certifi cate for shares of Lilly Stock to the Grantee, Lilly may require the
Grantee to pay to the Company any required withholding tax. The Committee may, in its discretion and subject
to such rules as the Committee may adopt, permit or require the Grantee to satisfy, in whole or in part, any
withholding tax requirement by having the Company withhold shares of Lilly Stock from the Grant having a fair
market value equal to the amount of the withholding tax. In the event the Grantee fails to pay the withholding
tax within the time period specifi ed in the Grant, the Committee may take whatever action it deems appropriate,
including withholding or selling suffi cient shares from the Grant to pay the tax and assessing interest or late
fees to the Grantee.
(d) Lapse of Restrictions. All restrictions imposed under the Restricted Stock Grant shall lapse (i) upon the
expiration of the Restriction Period if all conditions stated in Sections 7(a), (b) and (c) have been met or (ii) as
provided under Section 12(a)(ii). The Grantee shall then be entitled to delivery of the certifi cate.
(e) Total Number of Shares Granted. Not more than 3,000,000 shares of Lilly Stock may be issued or transferred
under the 2002 Plan in the form of Restricted Stock Grants and Stock Unit Awards, considered together.
8. Stock Option Grants to Nonemployee Directors
The Board may grant Stock Options to Nonemployee Directors and may determine the terms and conditions ap-
plicable to such Stock Options consistent with the following provisions:
(a) Option Price. The Board shall determine the price or prices at which Lilly Stock may be purchased by the
Nonemployee Director under a Stock Option (“Option Price”) which shall be not less than the fair market value
of Lilly Stock on the date the Stock Option is granted (the “Grant Date”). In the Board’s discretion, the Grant
Date of a Stock Option may be established as the date on which Board action approving the Stock Option is
taken or any later date specifi ed by the Board. Once established, the Option Price may not be reduced except in
the case of adjustments under Section 4(b).
(b) Option Exercise Period. The Board shall determine the option exercise period of each Stock Option. The period
shall not exceed ten years from the Grant Date. Unless the Board shall otherwise expressly provide in a Stock
Option agreement, in the event a Grantee’s service on the Board is terminated, any Stock Option held by such
Grantee shall remain exercisable for fi ve years after such termination (or until the end of the option exercise
period, if earlier). In the event a Nonemployee Director is removed from the Board for “cause” (as determined
in accordance with applicable state law and the Articles of Incorporation of Lilly), any Stock Option held by that
Nonemployee Director shall terminate immediately.
(c) Exercise of Option. A Stock Option will be deemed exercised by a Nonemployee Director upon delivery of (i) a
notice of exercise to Lilly or its representative as designated by the Board, and (ii) accompanying payment of
the Option Price if the Stock Option requires such payment at the time of exercise. The notice of exercise, once
delivered, shall be irrevocable.
(d) Satisfaction of Option Price. A Stock Option may require payment of the Option Price upon exercise or may specify
a period not to exceed 30 days following exercise within which payment must be made (“Payment Period”). The
Grantee shall pay or cause to be paid the Option Price in cash, or with the Board’s permission, by delivering (or
providing adequate evidence of ownership of) shares of Lilly Stock already owned by the Grantee and having a
fair market value on the date of exercise equal to the Option Price, or a combination of cash and such shares.
If the Grantee fails to pay the Option Price within the Payment Period, the Board shall have the right to take
whatever action it deems appropriate, including voiding the option exercise or voiding that part of the Stock
Option for which payment was not timely received. Lilly shall not deliver shares of Lilly Stock upon exercise of a
Stock Option until the Option Price and any required withholding tax are fully paid.
9. Stock Appreciation Rights to Eligible Employees.
The Committee may grant Stock Appreciation Rights to Eligible Employees. A Stock Appreciation Right is an award
in the form of a right to receive, upon exercise or settlement of the right but without other payment, an amount
based on appreciation in the fair market value of shares of Lilly Stock over a base price established for the Award.
Stock Appreciation Rights shall be settled or exercisable at such time or times and upon conditions as may be ap-
proved by the Committee, provided that the Committee may accelerate the settlement or exercisability of a Stock
Appreciation Right at any time. The following provisions are applicable to Stock Appreciation Rights:
(a) Freestanding Stock Appreciation Rights. A Stock Appreciation Right may be granted without any related Stock
Option, and in such case, will be settled or exercisable at such time or times as determined by the Committee,
but in no event after eleven years from the Grant Date. The Committee shall determine the base price of a Stock
Appreciation Right granted without any related Option, provided, however, that such base price per share shall
not be less than the fair market value of Lilly Stock on the Grant Date.
(b) Tandem Stock Appreciation Rights. A Stock Appreciation Right may be granted in connection with a Stock Option,
either at the time of grant or at any time thereafter during the term of the Stock Option. A Stock Appreciation
Right granted in connection with a Stock Option will entitle the holder, upon exercise, to surrender the Stock
Option or any portion thereof to the extent unexercised, with respect to the number of shares as to which such
Stock Appreciation Right is exercised, and to receive payment of an amount computed as described in Section
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9(c). The Stock Option will, to the extent and when surrendered, cease to be exercisable. A Stock Appreciation
Right granted in connection with a Stock Option hereunder will have a base price per share equal to the per
share exercise price of the Stock Option, will be exercisable at such time or times, and only to the extent,
that the related Stock Option is exercisable, and will expire no later than the related Stock Option expires. If a
related Stock Option is exercised in whole or in part, then the SAR related to the shares purchased terminates
as of the date of such exercise.
(c) Payment of Stock Appreciation Rights. A Stock Appreciation Right will entitle the holder, upon settlement or
exercise, as applicable, to receive payment of an amount determined by multiplying: (i) the excess of the fair
market value of a share of Lilly Stock on the date of settlement or exercise of the Stock Appreciation Right over
the base price of the Stock Appreciation Right, by (ii) the number of shares as to which the Stock Appreciation
Right is settled or exercised. Payment of the amount determined under the foregoing will be made in shares
of Lilly Stock valued at their fair market value on the date of settlement or exercise, as applicable, subject to
applicable tax withholding requirements.
(d) Limits on Individual Grants. No individual Grantee may be granted Stock Options or Stock Appreciation Rights,
considered together, under the 2002 Plan for more than 2,500,000 3,500,000 shares of Lilly Stock in any period
of three consecutive calendar years.
(e) Share Withholding. With respect to any Stock Appreciation Right, the Committee may, in its discretion and
subject to such rules as the Committee may adopt, permit or require the Grantee to satisfy, in whole or in
part, any withholding tax obligation which may arise in connection with the exercise or settlement of the right
by having the Company withhold shares of Lilly Stock having a fair market value equal to the amount of the
withholding tax.
10. Stock Unit Awards to Eligible Employees.
The Committee may grant Stock Unit Awards to Eligible Employees. A Stock Unit Award is an award of a number of
hypothetical share units with respect to shares of Lilly Stock that are granted subject to such vesting and transfer
restrictions and conditions of payment as the Committee shall determine and set forth in an award agreement.
The value of each unit under a Stock Unit Award is equal to the fair market value of the Lilly Stock on any applicable
date of determination. A Stock Unit Award shall be subject to such restrictions and conditions as the Committee
shall determine. A Stock Unit Award may be granted, at the discretion of the Committee, together with a dividend
equivalent right with respect to the same number of shares of Lilly Stock. The following provisions are applicable
to Stock Unit Awards:
(a) Vesting of Stock Unit Awards. On the Grant Date, the Committee shall determine any vesting requirements with
respect to a Stock Unit Award, which shall be set forth in the award agreement, provided that the Committee
may accelerate the vesting of a Stock Unit Award at any time. Vesting requirements may be based on the
continued employment of the Grantee with the Company for a specifi ed time period or periods. Vesting
requirements may also be based on the attainment of specifi ed performance goals or measures established by
the Committee. A Stock Unit Award may also be granted on a fully vested basis, with a deferred payment date.
(b) Payment of Stock Unit Awards. A Stock Unit Award shall become payable to a Grantee at the time or times
determined by the Committee and set forth in the award agreement, which may be upon or following the vesting
of the award. The payment with respect to each share unit under a Stock Unit Award shall be determined
by reference to the fair market value of Lilly Stock on each applicable payment date. Payment will be made
in shares of Lilly Stock or cash at the discretion of the Committee, subject to applicable tax withholding
requirements.
(c) Total Number of Shares Granted. Not more than 3,000,000 shares of Lilly Stock may be issued or transferred
under the 2002 Plan in the form of Restricted Stock Grants and Stock Unit Awards, considered together.
(d) (c) Share Withholding. With respect to any Stock Unit Award, the Committee may, in its discretion and subject
to such rules as the Committee may adopt, permit or require the Grantee to satisfy, in whole or in part, any
withholding tax obligation which may arise in connection with the payment of the award by having the Company
withhold shares of Lilly Stock having a fair market value equal to the amount of the withholding tax.
11. Amendment and Termination of the 2002 Plan.
(a) Amendment. The Board may amend or terminate the 2002 Plan, but no amendment shall (i) allow the repricing
of Stock Options or Stock Appreciation Rights at a price below the original Option Price or base price as
applicable; (ii) allow the grant of Stock Options or Stock Appreciation Rights at an Option Price (or base price
as applicable) below the fair market value of Lilly Stock on the Grant Date; (iii) increase the number of shares
authorized for issuance or transfer pursuant to Sections 4(a), 6(f)(ii), 7(e), or 10(c); or (iv) increase the maximum
limitations on the number of shares subject to Grants imposed under Sections 5(f), 5(g), 6(f)(i), or 9(d), unless in
any case such amendment receives approval of the shareholders of the Company.
(b) Termination of 2002 Plan; Resubmission to Shareholders. The 2002 Plan shall remain in effect until April 1420,
20202012 or until earlier terminated by the Board. To the extent required under Section 162(m) of the Code, the
material terms of the 2002 Plan will be submitted to the shareholders of the Company for reapproval not later
than the annual meeting of shareholders that occurs in 2007 2013 if the Plan has not been terminated at that
time.
(c) Termination and Amendment of Outstanding Grants. A termination or amendment of the 2002 Plan that occurs
after a Grant is made shall not result in the termination or amendment of the Grant unless the Grantee
consents or unless the Committee acts under Section 13(e). The termination of the 2002 Plan shall not impair
the power and authority of the Committee with respect to outstanding Grants. Whether or not the 2002 Plan has
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terminated, an outstanding Grant may be terminated or amended under Section 13(e) or may be amended (i)
by agreement of the Company and the Grantee consistent with the 2002 Plan or (ii) by action of the Committee
provided that the amendment is consistent with the 2002 Plan and is found by the Committee not to impair the
rights of the Grantee under the Grant.
12. Change in Control.
(a) Effect on Grants. The Committee may provide in the agreement relating to a Grant or at any later date, that upon
the occurrence of a Change in Control (as defi ned below) the following shall occur:
(i)
In the case of Stock Options, each outstanding Stock Option that is not then fully exercisable shall
automatically become fully exercisable and shall remain so for the period permitted in the agreement
relating to the Grant;
(ii) The Restriction Period on all outstanding Restricted Stock Grants shall automatically expire and all
restrictions imposed under such Restricted Stock Grants shall immediately lapse;
(iii) Each Grantee of a Performance Award for an Award Period that has not been completed at the time of the
Change in Control shall be deemed to have earned a minimum Performance Award equal to the product
of (y) such Grantee’s maximum award opportunity for such Performance Award, and (z) a fraction, the
numerator of which is the number of full and partial months that have elapsed since the beginning of
such Award Period to the date on which the Change in Control occurs, and the denominator of which is
the total number of months in such Award Period; provided, however, that nothing in this subsection shall
prejudice the right of the Grantee to receive a larger payment under such Performance Award pursuant
to the terms of the Award or under any other plan of the Company;
(iv) Each outstanding Stock Appreciation Right that is not then fully exercisable shall automatically become
fully exercisable and shall remain so for the period permitted in the agreement relating to the Grant; and
(v) Each outstanding Stock Unit Award shall fully and immediately vest and become payable.
(b) Change in Control. For purposes of the 2002 Plan, a Change in Control shall mean the happening of any of the
following events:
(i) The acquisition by any “person,” as that term is used in Sections 13(d) and 14(d) of the 1934 Act (other
than (w) the Company, (x) any subsidiary of the Company, (y) any employee benefi t plan or employee
stock plan of the Company or a subsidiary of the Company or any trustee or fi duciary with respect to
any such plan when acting in that capacity, or (z) Lilly Endowment, Inc.,) of “benefi cial ownership,” as
defi ned in Rule 13d-3 under the 1934 Act, directly or indirectly, of 15 percent or more of the shares of the
Company’s capital stock the holders of which have general voting power under ordinary circumstances to
elect at least a majority of the Board of Directors of the Company (or which would have such voting power
but for the application of the Indiana Control Share Statute) (“Voting Stock”); provided, however, that an
acquisition of Voting Stock directly from the Company shall not constitute a Change in Control;
(ii) The fi rst day on which less than two-thirds of the total membership of the Board of Directors of the
Company shall be Continuing Directors (as that term is defi ned in Article 13(f) of the Company’s Articles
of Incorporation);
(iii) Consummation of a merger, share exchange, or consolidation of the Company (a “Transaction”), other
than a Transaction which would result in the Voting Stock of the Company outstanding immediately
prior thereto continuing to represent (either by remaining outstanding or by being converted into voting
securities of the surviving entity) more than 50 percent of the Voting Stock of the Company or such
surviving entity immediately after such Transaction; or
(iv) A complete liquidation of the Company or a sale or disposition of all or substantially all the assets of the
Company, other than a sale or disposition of assets to any subsidiary of the Company.
13. General Provisions.
(a) Prohibitions Against Transfer. (i) Except as provided in part (ii) of this subparagraph, during a Grantee’s lifetime,
only the Grantee or his or her authorized legal representative may exercise rights under a Grant. Such persons
may not transfer those rights. The rights under a Grant may not be disposed of by transfer, alienation, pledge,
encumbrance, assignment, or any other means, whether voluntary, involuntary, or by operation of law, and
any such attempted disposition shall be void; provided, however, that when a Grantee dies, the personal
representative or other person entitled under a Grant under the 2002 Plan to succeed to the rights of the
Grantee (“Successor Grantee”) may exercise the rights. A Successor Grantee must furnish proof satisfactory
to the Company of his or her right to receive the Grant under the Grantee’s will or under the applicable laws of
descent and distribution.
(ii) Notwithstanding the foregoing, the Committee may, in its discretion and subject to such limitations and
conditions as the Committee deems appropriate, grant nonqualifi ed stock options (or amend previously-
granted options) on terms which permit the Grantee to transfer all or part of the stock option, for
estate or tax planning purposes or for donative purposes, and without consideration, to a member of
the Grantee’s immediate family (as defi ned by the Committee), a trust for the exclusive benefi t of such
immediate family members, or a partnership, corporation, limited liability company or similar entity the
equity interests of which are owned exclusively by the Grantee and/or one or more members of his or
her immediate family. No such stock option or any other Grant shall be transferable incident to divorce.
Subsequent transfers of a stock option transferred under this part (ii) shall be prohibited except for
transfers to a Successor Grantee upon the death of the transferee.
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(b) Substitute Grants. In the event of a business combination in which another corporation is combined
with the Company by reason of a corporate merger, consolidation, acquisition of stock or property,
reorganization or liquidation in which the Company is the surviving entity, the Committee may make
Grants to individuals who are or were employees, directors, or consultants to such other corporation in
substitution for stock options, performance awards, restricted stock grant, stock appreciation rights, or
stock unit awards granted to such individuals by such other corporation that are outstanding at the time
of the business combination (“Substituted Stock Incentives”). The terms and conditions of the substitute
Grants may vary from the terms and conditions that would otherwise be required by the 2002 Plan and
from those of the Substituted Stock Incentives. The Committee shall prescribe the exact provisions of
the substitute Grants, preserving where practical the provisions of the Substituted Stock Incentives.
The Committee shall also determine the number of shares of Lilly Stock to be taken into account under
Section 4.
(c) Subsidiaries. The term “subsidiary” means a corporation, limited liability company or similar form of
entity of which Eli Lilly and Company owns directly or indirectly 50 percent or more of the voting power.
(d) Fractional Shares. Fractional shares shall not be issued or transferred under a Grant, but the Committee
may pay cash in lieu of a fraction or round the fraction.
(e) Compliance with Law. The 2002 Plan, the exercise of Grants, and the obligations of the Company to issue
or transfer shares of Lilly Stock under Grants shall be subject to all applicable laws and regulations and
to approvals by any governmental or regulatory agency as may be required. The Committee may revoke
any Grant if it is contrary to law or modify a Grant to bring it into compliance with any valid and mandatory
law or government regulation. The Committee may also adopt rules regarding the withholding of taxes on
payment to Grantees.
(f) Ownership of Stock. A Grantee or Successor Grantee shall have no rights as a shareholder of the Company
with respect to any shares of Lilly Stock covered by a Grant until the shares are issued or transferred to
the Grantee or Successor Grantee on the Company’s books.
(g) No Right to Employment or to Future Grants. The 2002 Plan and the Grants under it shall not confer
upon any Eligible Employee or Grantee the right to continue in the employment of the Company or as a
member of the Board or affect in any way (i) the right of the Company to terminate the employment of an
Eligible Employee or Grantee at any time, with or without notice or cause, or (ii) any right of the Company
or its shareholders to terminate the Grantee’s service on the Board. Neither the status of an individual
as an Eligible Employee nor the receipt of one or more Grants by a Grantee shall confer upon the Eligible
Employee or Grantee any rights to future Grants.
(h) Foreign Jurisdictions. The Committee may adopt, amend, and terminate such arrangements and make
such Grants, not inconsistent with the intent of the 2002 Plan, as it may deem necessary or desirable to
make available tax or other benefi ts of the laws of foreign jurisdictions to Grantees who are subject to
such laws. The terms and conditions of such foreign Grants may vary from the terms and conditions that
would otherwise be required by the 2002 Plan.
(i) Governing Law. The 2002 Plan and all Grants made under it shall be governed by and interpreted in
accordance with the laws of the State of Indiana, regardless of the laws that might otherwise govern
under applicable Indiana confl ict-of-laws principles.
(j) Effective Date of the Amended 2002 Plan. The amended 2002 Plan is effective upon its approval by the
Company’s shareholders at the annual meeting to be held on April 1521, 20082, or any adjournment of
the meeting.
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Senior Management
Sidney Taurel
Chairman of the Board and Chief
Executive Offi cer 1
Andrew M. Dahlem, Ph.D.
Vice President, LRL Operations and
Lilly Research Laboratories, Europe
Anne Nobles.
Vice President, Compliance and
Enterprise Risk Management
John C. Lechleiter, Ph.D.
President and Chief Operating Offi cer 1
Frank M. Deane, Ph.D.
President, Manufacturing Operations
E. Paul Ahern, Ph.D.
Vice President, Global API
Manufacturing
Alecia A. DeCoudreaux
Vice President and General Counsel,
Lilly USA
Steven M. Paul, M.D.
Executive Vice President, Science
and Technology, and President, Lilly
Research Laboratories
Richard D. Pilnik.
Group Vice President and Chief
Marketing Offi cer
Derica W. Rice
Senior Vice President and Chief
Financial Offi cer
Gino Santini
Senior Vice President, Corporate
Strategy and Business Development
J. Carmel Egan, Ph.D.
Vice President, Project Management
Timothy R. Franson, M.D.
Vice President, Global Regulatory
Affairs
Thomas W. Grein
Vice President and Treasurer
Simon N. R. Harford
Vice President and Controller
Jeffrey N. Simmons
President, Elanco Animal Health
William F. Heath, Ph.D.
Executive Director, Bioproduct
Research and Development 3
Sharon L. Sullivan
Vice President, Human Resources,
Global Compensation and HR Services
Michael C. Heim
Vice President and Chief Information
Offi cer
Lorenzo Tallarigo, M.D..
President, International Operations 4
Abbas S. Hussain
President, European Operations
Jacques Tapiero
President, Intercontinental Operations
Peter J. Johnson
Executive Director, Corporate Strategy
Albertus J. van den Bergh
Vice President, Global Customer
Solutions 5
Elizabeth H. Klimes.
Vice President, Six Sigma
Patricia A. Martin
Vice President, Global Diversity
W. Darin Moody
Vice President, Corporate Engineering
and Continuous Improvement
Anthony J. Murphy, Ph.D.
Senior Vice President, Human
Resources
Thomas R. Verhoeven, Ph.D.
Vice President, Product Research and
Development 6
Fionnuala Walsh, Ph.D.
Vice President, Quality
James A. Ward
Vice President and Chief Procurement
Offi cer
Andreas F. Witzel
Vice President, Manufacturing,
European and Asian Drug Product
Robert A. Armitage
Senior Vice President and General
Counsel
Robert W. Armstrong, Ph.D.
Vice President, Global External
Research and Development
Alex M. Azar II
Senior Vice President, Corporate
Affairs and Communications
Alan Breier, M.D.
Vice President, Medical, and Chief
Medical Offi cer
Thomas F. Bumol, Ph.D.
Vice President, Biotech Discovery
Research and President, Applied
Molecular Evolution
Bryce D. Carmine.
President, Global Product
Development 2
William W. Chin, M.D.
Vice President, Discovery Research
and Clinical Investigation
Deirdre P. Connelly.
President, U.S. Operations
Newton F. Crenshaw
President and General Manager, Lilly
Japan
Maria Crowe
Vice President, Manufacturing,
Americas Drug Products
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Board of Directors
Sidney Taurel
Chairman of the Board and Chief Executive Offi cer 1
John C. Lechleiter, Ph.D.
President and Chief Operating Offi cer 1
Sir Winfried Bischoff
Chairman, Citigroup Inc.
J. Michael Cook
Retired Chairman and Chief Executive Offi cer, Deloitte & Touche LLP
Michael L. Eskew
Former Chairman and Chief Executive Offi cer, United Parcel Service, Inc. 7
Martin S. Feldstein, Ph.D.
President and Chief Executive Offi cer, National Bureau of Economic Research, and George F. Baker Professor of
Economics, Harvard University
George M.C. Fisher
Former Chairman of the Board and Chief Executive Offi cer, Motorola, Inc. and Eastman Kodak Company 8
J. Erik Fyrwald
Group Vice President, DuPont Agriculture & Nutrition
Alfred G. Gilman, M.D., Ph.D.
Executive Vice President for Academic Affairs and Provost, The University of Texas Southwestern Medical Center at
Dallas; Dean, Southwestern Medical School; and Regental Professor of Pharmacology and Director of the Cecil and Ida
Green Center for Molecular, Computational, and Systems Biology, The University of Texas Southwestern Medical Center
Karen N. Horn, Ph.D.
Retired President, Private Client Services, and Managing Director, Marsh, Inc.
Ellen R. Marram
President, The Barnegat Group LLC
Franklyn G. Prendergast, M.D., Ph.D.
Edmond and Marion Guggenheim Professor of Biochemistry and Molecular Biology and Professor of Molecular
Pharmacology and Experimental Therapeutics, Mayo Medical School; Director, Mayo Clinic Center for Individualized
Medicine; and Director Emeritus, Mayo Clinic Cancer Center
Kathi P. Seifert
Retired Executive Vice President, Kimberly-Clark Corporation
Notes
1Taurel will retire as chief executive offi cer effective March 31, 2008, and as chairman of the board effective December 31, 2008.
Effective April 1, 2008, Lechleiter will assume the role of president and chief executive offi cer.
2Effective April 1, 2008, Carmine will assume the role of executive vice president, global marketing and sales.
3Effective April 1, 2008, Heath will assume the role of vice president, product research and development.
4Effective March 31, 2008, Tallarigo will retire from the company.
5Effective March 31, 2008, van den Bergh will retire from the company.
6Effective April 1, 2008, Verhoeven will assume the role of president, global product development.
7Eskew was elected to the board February 18, 2008.
8Fisher will retire from the board effective April 21, 2008.
125
Corporate Information
Annual meeting
The annual meeting of shareholders will be held at the
Lilly Center Auditorium, Lilly Corporate Center, India-
napolis, Indiana, on Monday, April 21, 2008, at 11:00 a.m.
EDT. For more information, see the proxy statement sec-
tion of this report, beginning on page 60.
10-K and 10-Q reports
Paper copies of the company’s annual report to the
Securities and Exchange Commission on Form 10-K and
quarterly reports on Form 10-Q are available upon written
request to:
Eli Lilly and Company
P.O. Box 88665
Indianapolis, Indiana 46208-0665
To access these reports more quickly, you can fi nd all of
our SEC fi lings online at: http://investor.lilly.com/edgar.
cfm
Stock listings
Eli Lilly and Company common stock is listed on the New
York, London, and Swiss stock exchanges. NYSE ticker
symbol: LLY. Most newspapers list the stock as “Lilly (Eli)
and Co.”
CEO and CFO certifi cations
The company’s chief executive offi cer and chief fi nancial
offi cer have provided all certifi cations required under
Securities and Exchange Commission regulations with
respect to the fi nancial information and disclosures in
this report. The certifi cations are available as exhibits to
the company’s Form 10-K and 10-Q reports.
In addition, the company’s chief executive offi cer has fi led
with the New York Stock Exchange a certifi cation to the
effect that, to the best of his knowledge, the company is
in compliance with all corporate governance listing stan-
dards of the Exchange.
Transfer agent and registrar
Wells Fargo Shareowner Services
Mailing address:
Shareowner Relations Department
P.O. Box 64854
St. Paul, Minnesota 55164-0854
Overnight address:
161 North Concord Exchange
South St. Paul, Minnesota 55075
Telephone: 1-800-833-8699
E-mail: stocktransfer@wellsfargo.com
Internet: http://www.wellsfargo.com/com/shareowner_
services
Dividend reinvestment and stock purchase plan
Wells Fargo Shareowner Services administers the Share-
owner Service Plus Plan, which allows registered share-
holders to purchase additional shares of Lilly common
stock through the automatic investment of dividends.
The plan also allows registered shareholders and new
investors to purchase shares with cash payments, either
by check or by automatic deductions from checking or
savings accounts. The minimum initial investment for
new investors is $1,000. Subsequent investments must be
at least $50. The maximum cash investment during any
calendar year is $150,000. Please direct inquiries concern-
ing the Shareowner Service Plus Plan to:
Wells Fargo Shareowner Services
Shareowner Relations Department
P.O. Box 64854
St. Paul, Minnesota 55164-0854
Telephone: 1-800-833-8699
Online delivery of proxy materials
Shareholders may elect to receive annual reports and
proxy materials online. This reduces paper mailed to the
shareholder’s home and saves the company printing and
mailing costs. To enroll, go to http://proxyonline.lilly.com
and follow the directions provided.
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126
Annual Meeting Admission Ticket
Eli Lilly and Company 2008 Annual Meeting of Shareholders
Monday, April 21, 2008
11 a.m. EDT
Lilly Center Auditorium
Lilly Corporate Center
Indianapolis, Indiana 46285
The top portion of this page will be required for admission to the meeting.
Please write your name and address in the space provided below and present this ticket when you enter the Lilly
Center.
A reception (beverages only) will be held from 10:00 a.m. to 10:45 a.m. in the Lilly Center.
Name
Address
City, State, and Zip Code
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Detach here
Directions and Parking
From I-70 take Exit 79B; follow signs to McCarty Street. Turn right (east) on McCarty Street; go straight into
Lilly Corporate Center. You will be directed to parking. Be sure to take the admission ticket (the top portion of this
page) with you to the meeting and leave this parking pass on your dashboard.
127
Take the top portion of this page with you to the meeting.
Detach here
D
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Eli Lilly and Company
Annual Meeting of Shareholders
April 21, 2008
Complimentary Parking
Lilly Corporate Center
Please place this identifi er on the dashboard of your car as you enter Lilly Corporate
Center so it can be clearly seen by security and parking personnel.
128
On the Cover
Candy Edwards is a wife, mother, grandmother and self-taught artist
with a passion for helping others. She also is a Cymbalta® patient.
Just two years ago, Candy developed a staph infection that kept her
9 Beyond Medicine: Providing Answers That Matter
6
Innovation at Lilly: The Portfolio and the Pipeline
Year in Review
1 Financial Highlights
2 Letter to Shareholders
Financials
hospitalized and bedridden for several months. The infection was so
severe that it nearly killed her. Although Candy survived, she found
herself in a world of intense pain, fear, anger and despair. The spirited
woman her family, friends and community knew so well soon became
someone they hardly recognized. Candy lost interest in everything she
cared about—even her family and her art.
“I cried all the time and I had terrible mood swings,” said Candy. “I felt
like I was in this deep hole—it was like I was pinned down. Suicide
seemed to be the only way out.”
Fortunately, Candy’s husband of 30 years, Freddie, recognized that
something was seriously wrong with the woman he loved, and he
pleaded with her to talk to her doctor. Although she was reluctant
at fi rst to accept her diagnosis of depression and initially refused to
take the medicine her doctor gave her, Candy eventually decided to
give it a try.
Candy’s doctor had prescribed Cymbalta, and she recalls that within a
“Cymbalta works for me,” she said. The turning point was the day she
woke up and decided to put on her make-up—something she hadn’t
done for nearly 6 months. “I fi nally started to feel like I was back.”
Today, Candy is using her love of art to help raise awareness about
highway safety in her home state of Georgia. She has created
characters such as “Boostie,” who promotes the importance of booster
seats for young children, and “Buckley,” a character who encourages
motorists to wear seatbelts.
Candy isn’t shy about telling her story to others, and by doing so she
has become a source of hope and inspiration for others suffering from
depression in her community.
10 Review of Operations
14 Consolidated Statements of Income
19 Consolidated Balance Sheets
20 Consolidated Statements of Cash Flows
21 Consolidated Statements of Comprehensive Income
30 Segment Information
31 Selected Quarterly Data
32 Selected Financial Data
33 Notes to Consolidated Financial Statements
57 Management’s Reports
58 Report of Independent Registered Public Accounting Firm
Proxy Statement
61 General Information
65 Board of Directors
69 Highlights of the Company’s Corporate Governance Guidelines
77 Directors and Corporate Governance Committee Matters
78 Audit Committee Matters
80 Compensation Committee Matters
81 Executive Compensation
101 Ownership of Company Stock
102
Items of Business To Be Acted Upon at the Meeting
115 Other Matters
Corporate Information
week, she could tell a difference.
60 Notice of 2008 Annual Meeting and Proxy Statement
“I always tell them to talk to their physician,” Candy said. “If I hadn’t
124 Senior Management and Board of Directors
sought help, I might have lost everything. I have my family and my life
126 Corporate Information
back. It was a blessing.”
127 Annual Meeting Admission Ticket
Trademarks
Actos®
Alimta®
Arxxant®
Axid®
Byetta®
Ceclor®
Cialis®
Coban®
Cymbalta®
Effi ent™
Evista®
Forteo®
Gemzar®
Humalog®
Humatrope®
Humulin®
Permax®
Prozac®
Prozac® Weekly™
ReoPro®
Rumensin®
Strattera®
Surmax®
Symbyax®
Tylan®
Vancocin®
Xigris®
Yentreve®
Zyprexa®
Zyprexa® Zydis®
(pioglitazone hydrochloride)
(pemetrexed disodium)
(ruboxistaurin mesylate)
(nizatidine)
(exenatide injection)
(cefaclor)
(tadalafi l)
(monensin sodium), Elanco
(duloxetine hydrochloride)
(prasugrel)
(raloxifene hydrochloride)
(teriparatide of recombinant DNA origin)
(gemcitabine hydrochloride)
(insulin lispro of recombinant DNA origin)
(somatropin of recombinant DNA origin)
(human insulin of recombinant DNA origin)
(pergolide mesylate)
(fl uoxetine hydrochloride)
(fl uoxetine hydrochloride)
(abciximab), Centocor
(monensin sodium), Elanco
(atomoxetine hydrochloride)
(avilamycin), Elanco
(olanzapine/fl uoxetine hydrochloride)
(tylosin), Elanco
(vancomycin hydrochloride)
(drotrecogin alfa [activated])
(duloxetine hydrochloride)
(olanzapine)
(olanzapine)
Actos® is a trademark of Takeda Chemical Industries, Ltd.
AIR® is trademark of Alkermes, Inc.
Axid® is a trademark of Reliant Pharmaceuticals, LLC.
Byetta® is a trademark of Amylin Pharmaceuticals, Inc.
Cialis® is a trademark of Lilly ICOS LLC.
EVA® is a trademark of Stern Stewart & Co.
Sarafem® is a trademark of Galen (Chemicals) Limited
Vancocin® is a trademark of ViroPharma Incorporated
Zydis® is a trademark of Cardinal Health.
All trademarks listed above are trademarks of Eli Lilly and Company unless otherwise noted.
For More Information
Lilly corporate responsibility and report of political fi nancial support . . www.lilly.com/about/citizenship/index.html
Lilly clinical trials registry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . www.lillytrials.com
Lilly Grant Offi ce . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . www.lillygrantoffi ce.com
Multi-drug resistant tuberculosis initiative . . . . . . . . . . . . . . . . . . . . . . . . . www.lillymdr-tb.com
Medicare prescription drug coverage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . www.lillymedicareanswers.com
Pharmaceutical industry patient assistance programs . . . . . . . . . . . . . . . www.pparx.org
Lilly Cares. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . www.lillycares.com or call toll-free 1-800-545-6962
© 2008 Eli Lilly and Company
2007AR
Eli Lilly and Company
2007 Annual Report
Notice of 2008
Annual Meeting
Proxy Statement
Eli Lilly and Company
Lilly Corporate Center
Indianapolis, Indiana 46285 USA
www.lilly.com