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Harvard Bioscience

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FY2017 Annual Report · Harvard Bioscience
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Solutions to Advance Life Science

2017 ANNUAL REPORTRevolutionizing Neuroscience ResearchHARVARD BIOSCIENCE   •   ANNUAL REPORT 2017Financial Highlights

Revenues
($ U.S. in thousands)

108,663

108,664

105,171

104,521

101,882

2017 Revenues by Region
(Revenues originating from region)

Jeff Duchemin

Jeffrey A. Duchemin was 

appointed Chief Executive 

Officer on August 26, 2013.  

He assumed the additional 

roles of President on 

November 1, 2013 and  

Director on October 29, 

2013. Prior to joining 

Harvard Bioscience,  

Mr. Duchemin spent 16 

years with Becton Dickinson 

(BD) in progressive sales, 

marketing and executive 

leadership positions 

across BD’s three business 

segments;  

BD Medical Systems,  

BD Diagnostic Systems,  

and BD Biosciences.  

Mr. Duchemin earned an 
M.B.A. from Southern  

New Hampshire University  

and a B.S. in accounting 

from the University of 

Massachusetts Dartmouth.

65% United States

15% United Kingdom

11% Germany

9% Rest of the World

Employees by Country
(As of December 31, 2017)

FY13

FY14

FY15

FY16

FY17

Non-GAAP Adjusted Income  
from Continuing Operations
($ U.S. in thousands)

8,893

7,062

4,980

4,405

4,224

FY13

FY14

FY15

FY16

FY17

Non-GAAP Adjusted Diluted EPS
($ U.S.)

0.27

0.22

0.15

0.13

56% United States

21% Germany

11% United Kingdom

6% Spain

0.12

2% Canada

2% Sweden

1% China

0% France

FY13

FY14

FY15

FY16

FY17

In this annual report, we have included non-GAAP financial 
information including adjusted income and adjusted earnings 
per diluted share from continuing operations. We believe that 
this non-GAAP financial information provides investors with an 
enhanced understanding of the underlying operations of the 
business. This non-GAAP financial information approximates 
information used by our management to internally evaluate 
our results. In particular, we believe that the presentation 

of non-GAAP adjusted income from continuing operations, 
including a number of adjusted line items, provides investors 
with a clearer understanding of the full effect of the adjustments 
that we make to our GAAP income and earnings per diluted 
share from continuing operations in order to derive our non-
GAAP adjusted income and earnings per diluted share from 
continuing operations. A tabular reconciliation of these non-
GAAP adjusted results can be found at Exhibit 1 and 2.

H A R V A R D   B I O S C I E N C E ,   I N C .     •     2 0 1 7   A N N U A L   R E P O R T

Financial Performance

Selected Financial Data

For The Year Ended December 31,

2017  

2016  

2015  

2014  

2013

(in thousands, except per share data)

Statement of Operations Data:

Revenues ........................................................................................

$ 101,882  $ 104,521  $ 108,664  $ 108,663  $ 105,171 

Cost of revenues ............................................................................

   54,285      56,106     59,941     59,319     57,475 

Gross profit...............................................................................

   47,597     48,415     48,723     49,344     47,696 

Operating expenses .......................................................................

   47,698     51,412     50,436     42,726     46,159 

Operating (loss) income ...........................................................

(101 )    

(2,997 )    

(1,713 )     6,618     1,537 

Other expense, net ..................................................................

(1,987 )   

(81 )   

(1,895 )   

(2,201 )   

(1,102 )

(Loss) income from continuing operations before income taxes ..

   (2,088)     (3,078)    

(3,608 )     4,417    

435 

Income tax (benefit) expense .........................................................

(1,223 )    1,229    15,431    2,062   

(288)

(Loss) income from continuing operations ...............................

(865 )    

(4,307 )    (19,039 )     2,355    

723 

Discontinued operations:

Loss from discontinued operations, net of tax .........................

–     

–     

–     

–      

(2,553 )

Net (loss) income......................................................................

$ 

(865 ) $  (4,307 ) $ (19,039 ) $  2,355 $  (1,830 )

(Loss) earnings per share:

Basic (loss) earnings per common share from continuing operations .. $ 

(0.02 )  $ 

(0.13 )  $ 

(0.57 )  $ 

0.07  $ 

0.02 

Discontinued operations ..........................................................

–     

–     

–     

–     

(0.08 )

Basic (loss) earnings per common share ..................................

$ 

(0.02 )  $ 

(0.13 )  $ 

(0.57 )  $ 

0.07 $ 

(0.06 )

Diluted (loss) earnings per common share from continuing operations .... $ 

(0.02 )  $ 

(0.13 )  $ 

(0.57 )  $ 

0.07  $ 

0.02 

Discontinued operations ..........................................................

–     

–     

–     

–     

(0.08 )

Diluted (loss) earnings per common share ...............................

$ 

(0.02 ) $ 

(0.13 ) $ 

(0.57 ) $ 

0.07 $ 

(0.06 )

Weighted average common shares:

Basic .........................................................................................

   34,753     34,212     33,593     32,171     30,384 

Diluted .....................................................................................

   34,753     34,212     33,593     33,237     31,914 

As of December 31,

2017  

2016  

2015  

2014  

2013

(in thousands)

Balance Sheet Data:

Cash and cash equivalents .......................................................

$  5,733  $  5,596  $  6,744  $ 14,134  $ 25,771 

Working capital ........................................................................

   33,494     30,871     31,226    38,964     44,665 

Total assets ...............................................................................

  109,354    107,765    120,050    135,916    135,460 

Long-term debt, net of current portion ...................................

   8,983     11,374     16,369     16,450     19,750 

Stockholders’ equity .................................................................

   80,900     72,196     77,598     95,468     94,485 

Please refer to Item 6 beginning on page 20 in our Annual Report on Form 10-K for the year ended 
December 31, 2017, included herein, for footnotes to our Selected Financial Data.

W W W . H A R V A R D B I O S C I E N C E . C O M

Robert Gagnon

Mr. Gagnon was appointed 

Chief Financial Officer  

on November 1, 2013.  

Prior to joining the 

company he was recently 

Executive Vice President, 

Chief Financial Officer and 

Treasurer at Clean Harbors, 

Inc. (NYSE:CLH), a leading 

provider of environmental, 

energy and industrial  

services throughout  

North America. Prior to this,  

he served in progressive  

executive positions at  

Biogen Idec, Inc.,  

a Fortune 500 company  

developing treatments in 

the areas of immunology 

and neurology. Earlier, he 
worked in a variety of senior 

positions at Deloitte & 

Touche, LLP, and  

PricewaterhouseCoopers, 

LLP. He holds an M.B.A. 

from the MIT Sloan School 

of Management and a  

bachelor of arts degree  

in accounting from  

Bentley College.

 
  
  
  
  
 
 
 
 
HEKA

HEKA Elektronik (HEKA)  
is a developer, manufacturer 

and marketer of precision 

electrophysiology  

equipment specializing  

in both manual and 

automated Patch Clamp 

Amplifier systems.  

HEKA also specializes  

in instrumentation  

and equipment for  

Electrochemistry.

Dear Fellow Shareholders

During 2017, Harvard Bioscience continued to build a strong foundation for long 
term success. Our teams did a great job executing to our strategy as our commercial 
initiatives took hold. Highlights from 2017 include:

•  Three consecutive quarters of topline organic growth beginning with  

the second quarter of 2017.

•  Our electrophysiology product lines, including our Multi Channel Systems,  
  Triangle BioSystems, HEKA Elektronik, and Warner brands, were the primary  
  growth drivers during 2017. The integrated portfolio of products makes  
  Harvard Bioscience a leading provider of electrophysiology products  

for our customers on a global basis.  

•  Our revenue in the U.S. grew at least 2% organically for the last three  
  quarters of 2017. 

•  Topline growth in China continued a strong trend, growing 15% in 2017.

•  Our results in Europe ended the year strongly. Constant currency revenue  
  growth in Europe for the fourth quarter of 2017 was 7%.

•  Academic research funding from the National Institutes of Health had a  
strong year. For the year ended December 31, 2017, NIH outlays to  

  academic labs increased 8%.

In addition to the commercial successes of 2017, our entire organization has spent the last 
three years executing to our strategy. From implementing commercial initiatives, launching 
ERP platforms, consolidating facilities, and initiating prudent cost containment measures, 
we have built a foundation to be able to acquire and integrate a transformative acquisition. 
That hard work paid off in January of 2018 when we announced the sale of Denville 
Scientific and the acquisition of Data Sciences International. 

Introduction to Data Sciences International
Data Sciences International, or DSI, is a developer, manufacturer and marketer of 
telemetry, instrumentation, software and services that help advance science. DSI, which 
recorded revenue of approximately $44 million during 2017, is a recognized global leader 
in pre-clinical physiologic monitoring. Based in St. Paul, MN, DSI’s products are used in 
four primary research areas, including Basic, Drug Discovery, Safety Pharmacology, and 
Toxicology Research. DSI serves customers across many industries, from biopharma to 
contract research organizations and academic and government labs. 

The sale of Denville and acquisition of DSI transformed Harvard Bioscience into a pure 
play life science instrumentation company with competitive advantages across our 
portfolio. We are a larger organization, less susceptible to fluctuations in academic 
research funding, with improved profitability. As most of you know, Harvard Bioscience 
has historically been heavily weighted in academia. More than 70% of our global revenue 
comes from customers in academic labs with the remainder from a mix of pharma, 
biotech, government and other customers. For the past several years, the global

H A R V A R D   B I O S C I E N C E ,   I N C .     •     2 0 1 7   A N N U A L   R E P O R T

 
 
 
academic markets have been flat or grown more slowly than other end markets.  
We have continued to focus on diversifying our customer mix to take advantage 
of faster growing markets.  Executing on these two transactions does just 
that.  DSI’s revenue from academic customers is almost an inverse of Harvard 
Bioscience’s customer mix.  On an ongoing pro-forma basis, our mix will now 
be closer to 60% revenue from academic customers and 40% from biopharma, 
contract research organizations, and government.  This diversification makes 
our organization less susceptible to fluctuations in academic research funding.  
We see a tremendous cross selling opportunity of DSI products into more 
academic labs, as well as our legacy brands into the biopharma and CRO 
markets.  Nothing exemplifies this opportunity more than each company’s top 
customers.  There is almost no overlap in each company’s top 25 customers.

In addition to a diversified customer mix, our financial profile will significantly 
improve. By acquiring DSI our company has become more profitable moving 
forward. For 2018, we anticipate our adjusted gross margins and adjusted 
operating margins to increase to mid-50% and increase to the low double 
digits, respectively.

Looking Ahead…
When I took over as Harvard Bioscience’s President and CEO over four years 
ago, I knew we would become a successful company if we executed on four 
corporate initiatives – commercial excellence, operational efficiency, product 
development, and acquisitions. In that time, we’ve worked tremendously hard 
to organically grow the topline, develop and bring new products to market, 
implement ERP systems, consolidate facilities, all while focusing on cost 
containment initiatives. We experienced several headwinds along the way, but 
that never deterred us from our goals. Today is not the end of the story, today  
is the beginning of a new chapter for Harvard Bioscience; a pure play life 
science instrumentation company with new topline and bottom-line growth 
potential and several new competitive advantages that differentiate ourselves 
from our competitors.

The future is bright. 2018 should be a banner year for Harvard Bioscience and 
its shareholders. We appreciate the commitment and continued support and 
look forward to sharing the future success of Harvard Bioscience with you all.

Sincerely,

Jeffrey A. Duchemin
President & Chief Executive Officer

W W W . H A R V A R D B I O S C I E N C E . C O M

MCS

Multi-Channel Systems  
is a developer, manufacturer 

and marketer of precision 

scientific measuring  

instrumentation and 

equipment in the field of 

Electrophysiology including, 

data acquisition systems,  

for use with custom  

amplifier configurations,  

in vivo-systems designed  

for recordings with  

microelectrode arrays,  

and in vitro-systems for  

extracellular recordings 

from microelectrode arrays.

TBSI

Triangle BioSystems

Triangle BioSystems (TBSI) 
is a developer, manufacturer 

and marketer of in vivo  

neural interface systems to 

aid neuroscience research, 

especially in the fields of 

Electrophysiology,  

Psychology, Neurology and 

Pharmacology. This includes 

both wireless and tethered 

systems for both stimulation 

and recording.

Corporate Information

Our Company
Harvard Bioscience, Inc., a Delaware corporation, is a global developer, manufacturer and 
marketer of a broad range of scientific instruments and systems used to advance life science 
for basic research, drug discovery, clinical and environmental testing. Our products are sold to 
thousands of researchers in over 100 countries through our global sales organization, websites, 
catalogs, and through distributors including Thermo Fisher Scientific Inc., VWR, and other 
specialized distributors. We have sales and manufacturing operations in the United States, 
the United Kingdom, Germany, Sweden, Spain, France, Canada and China. Our vision is to 
be a world-leading life science company that excels in meeting the needs of our customers 
by providing a wide breadth of innovative products and solutions, while providing exemplary 
customer service.

Transfer Agent  
& Registrar
Computershare Limited 
250 Royall Street 
Canton, MA 02021

Annual Meeting  
of Stockholders
The Annual Meeting of 
Stockholders of Harvard 
Bioscience, Inc. will be held on 
Thursday, May 17, 2018 at 11:00 
a.m. local time, at the offices of 
Burns & Levinson LLP, 125 Summer 
Street, Boston, MA 02110.  

Investor Relations
To obtain copies of this annual 
report or other financial 
information, please write or call:

Investor Relations 
Harvard Bioscience, Inc.  
84 October Hill Road  
Holliston, Massachusetts 01746 
508-893-8066

Dividends
Harvard Bioscience, Inc. has never 
declared or paid cash dividends 
on its common stock and currently 
has no plans to do so in the 
foreseeable future.

Board of Directors
Jeffrey A. Duchemin 
Our President &  
Chief Executive Officer

Katherine A. Eade 
Deputy General Counsel 
La-Z-Boy, Inc.

James W. Green 
General Partner 
Grantchester Group

John F. Kennedy 
Formerly President & CFO  
Nova Ventures Corporation

Earl R. Lewis 
Chairman 
FLIR Systems, Inc.

Thomas W. Loewald 
Division President 
ProAmpac

Bertrand Loy 
President & CEO 
Entegris, Inc.

George Uveges 
Principal 
Tallwood Group

Price Range of  
Common Stock
Year Ended December 31, 2017

Quarter 
First 
Second 
Third 
Fourth 

  High 
$  3.25 
$  2.75 
$  3.75 
$  3.80 

FY 2017 average 
FY 2017 closing 

  Low 
$  2.55  
$  2.30  
$  2.35  
$  3.08

$  2.92  
$  3.30

Year Ended December 31, 2016

Quarter 
First 
Second 
Third 
Fourth 
FY 2016 average 
FY 2016 closing 

  High 
$  3.25 
$  3.83 
$  3.19 
$  3.05 

  Low 
$  2.48  
$  2.72  
$  2.53  
$  2.30 
$  2.84  
$  3.05

Management
Jeffrey A. Duchemin 
President &  
Chief Executive Officer

Robert E. Gagnon 
Chief Financial Officer

Yong Sun 
Vice President,  
Commercial Operations

Stock Profile
Since the Company’s initial public 
offering on December 7, 2000, 
shares of Harvard Bioscience, Inc. 
have been quoted on the Nasdaq 
Global Market, and currently trade 
under the symbol “HBIO”.

As of March 9, 2018, the Company 
had 116 stockholders of record. 
The Company believes that the 
number of beneficial owners of 
our common stock at that date was 
substantially greater.

Corporate Address
Harvard Bioscience, Inc. 
84 October Hill Road  
Holliston, Massachusetts 01746 
www.harvardbioscience.com

Independent Registered 
Public Accounting Firm
Grant Thorton LLP 
75 State Street 
Boston, Massachusetts 02109 
www.grantthornton.com

General Counsel 
Burns & Levinson LLP 
125 Summer Street  
Boston, Massachusetts 02110

H A R V A R D   B I O S C I E N C E ,   I N C .     •     2 0 1 7   A N N U A L   R E P O R T

 
 
 
 
UNITED STATES  
SECURITIES AND EXCHANGE COMMISSION  
Washington, D.C. 20549 

☒ 

☐ 

FORM 10-K 
Annual report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934  

For the fiscal year ended December 31, 2017 
or  
Transition report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934  
For the transition period from              to               
Commission File Number 001-33957 

HARVARD BIOSCIENCE, INC.  
(Exact Name of Registrant as Specified in Its Charter) 

Delaware 
(State or other jurisdiction of Incorporation or organization) 

04-3306140 
(I.R.S. Employer Identification No.) 

84 October Hill Road, Holliston, Massachusetts 01746 
(Address of Principal Executive Offices, including zip code) 

(508) 893-8999  
(Registrant’s telephone number, including area code) 
Securities registered pursuant to Section 12(b) of the Act: 

Title of each class 
Common Stock, $0.01 par value 

Name of each exchange on which registered 
The NASDAQ Global Market  

Securities registered pursuant to Section 12(g) of the Act: 
None 

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. YES ☐    NO ☒ 

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. YES ☐    NO ☒ 

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 
1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing 
requirements for the past 90 days. YES ☒    NO ☐ 

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate web site, if any, every Interactive Data File 
required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant 
was required to submit and post such files). YES ☒    NO ☐ 

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to 
the best of registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment 
to this Form 10-K. ☐ 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. 

See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one): 

Large accelerated filer ☐ 

Non-accelerated filer ☐ 

(Do not check if a smaller reporting company) 

Accelerated filer ☒ 

Smaller reporting company ☐ 

Emerging growth company ☐ 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any 

new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐  

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act. YES ☐    NO ☒ 

The  aggregate  market  value  of  28,652,635  shares  of  voting  common  equity  held  by  non-affiliates  of  the  registrant  as  of  June  30,  2017  was 
approximately $73,064,219 based on the closing sales price of the registrant’s common stock, par value $0.01 per share on that date. Shares of the registrant’s 
common stock held by each officer and director and each person known to the registrant to own 10% or more of the outstanding voting power of the registrant 
have been excluded in that such persons  may be deemed affiliates. This determination of affiliate status is not a determination for other purposes. The 
registrant has no shares of non-voting common stock authorized or outstanding. 

At March 9, 2018, there were 35,594,802 shares of the registrant’s common stock issued and outstanding. 

DOCUMENTS INCORPORATED BY REFERENCE  

Portions of the Company’s definitive Proxy Statement in connection with the 2018 Annual Meeting of Stockholders (the “Proxy Statement”), to be 
filed within 120 days after the end of the Registrant’s fiscal year, are incorporated by reference into Part III  of this Form 10-K. Except with respect to 
information specifically incorporated by reference in this Form 10-K, the Proxy Statement is not deemed to be filed as part hereof. 

  
 
 
  
 
 
  
  
  
HARVARD BIOSCIENCE, INC.  
TABLE OF CONTENTS 
ANNUAL REPORT ON FORM 10-K 
For the Year Ended December 31, 2017 
INDEX  

Page 

PART I  

  Item 1. 

Business .........................................................................................................................................................  1 

  Item 1A.  Risk Factors ...................................................................................................................................................  7 

  Item 1B.  Unresolved Staff Comments ..........................................................................................................................  18 

  Item 2. 

Properties .......................................................................................................................................................  18 

  Item 3. 

Legal Proceedings .........................................................................................................................................  18 

  Item 4. 

Mine Safety Disclosures ................................................................................................................................  18 

PART II  

Item 5. 

Market for Registrant's Common Equity, Related Stockholder Matters and Issuer Purchases of Equity 
Securities .......................................................................................................................................................  19 

  Item 6. 

Selected Financial Data .................................................................................................................................  20 

  Item 7. 

Management's Discussion and Analysis of Financial Condition and Results of Operations .........................  22 

  Item 7A.  Quantitative and Qualitative Disclosures about Market Risk ........................................................................  37 

  Item 8. 

Financial Statements and Supplementary Data ..............................................................................................  37 

  Item 9. 

Changes in and Disagreements with Accountants on Accounting and Financial Disclosure ........................  37 

  Item 9A.  Controls and Procedures ................................................................................................................................  37 

  Item 9B.  Other Information ..........................................................................................................................................  41 

PART III 

  Item 10.  Directors, Executive Officers and Corporate Governance .............................................................................  41 

  Item 11. 

Executive Compensation ...............................................................................................................................  41 

  Item 12. 

Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters ......  41 

  Item 13. 

Certain Relationships and Related Transactions, and Director Independence ...............................................  41 

  Item 14. 

Principal Accounting Fees and Services ........................................................................................................  41 

PART IV 

  Item 15. 

Exhibits, Financial Statement Schedules .......................................................................................................  42 

Index to Consolidated Financial Statements ..................................................................................................  F-1 

Signatures 

  
  
  
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
  
    
  
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
  
    
  
  
    
  
  
    
    
  
  
    
  
 
This  Annual  Report  on  Form  10-K  contains  statements  that  are  not  statements  of  historical  fact  and  are  forward-
looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange 
Act of 1934 (Exchange Act), each as amended. The forward-looking statements are principally, but not exclusively, contained 
in  “Item  1:  Business”  and  “Item  7:  Management’s  Discussion  and  Analysis  of  Financial  Condition  and  Results  of 
Operations.” These statements involve known and unknown risks, uncertainties and other factors that may cause our actual 
results,  performance  or  achievements  to  be  materially  different  from  any  future  results,  performance  or  achievements 
expressed  or  implied  by  the  forward-looking  statements.  Forward-looking  statements  include,  but  are  not  limited  to, 
statements  about  management’s  confidence or  expectations,  our business  strategy,  our ability  to  raise  capital  or borrow 
funds to consummate acquisitions and the availability of attractive acquisition candidates, our expectations regarding future 
costs of product revenues, our anticipated compliance with the covenants contained in our credit facility, the adequacy of 
our financial resources and our plans, objectives, expectations and intentions that are not historical facts. In some cases, you 
can identify forward-looking statements by terms such as “may,” “will,” “should,” “could,” “would,” “seek,” “expects,” 
“plans,”  “aim,”  “anticipates,”  “believes,”  “estimates,”  “projects,”  “predicts,”  “intends,”  “think,”  “strategy,” 
“potential,”  “objectives,”  “optimistic,”  “new,”  “goal”  and  similar  expressions  intended  to  identify  forward-looking 
statements. These statements reflect our current views with respect to future events and are based on assumptions and subject 
to  risks  and  uncertainties.  Given  these  uncertainties,  you  should  not  place  undue  reliance  on  these  forward-looking 
statements. We discuss many of these risks in detail under the heading “Item 1A. Risk Factors” beginning on page 7 of this 
Annual Report on Form 10-K. You should carefully review all of these factors, as well as other risks described in our public 
filings, and you should be aware that there may be other factors, including factors of which we are not currently aware, that 
could cause these differences. Also, these forward-looking statements represent our estimates and assumptions only as of the 
date of this report. We may not update these forward-looking statements, even though our situation may change in the future, 
unless  we  have  obligations  under  the  federal  securities  laws  to  update  and  disclose  material  developments  related  to 
previously disclosed information. Harvard Bioscience, Inc. is referred to herein as “we,” “our,” “us,” and “the Company.” 

Item 1. 

Business.  

Overview  

PART I  

Harvard Bioscience, Inc., a Delaware corporation, is a global developer, manufacturer and marketer of a broad range 
of  scientific  instruments  and  systems  used  to  advance  life  science  for  basic  research,  drug  discovery,  clinical  and 
environmental  testing.  Our  products  are  sold  to  thousands  of  researchers  in  over  100  countries  through  our  global  sales 
organization, websites, catalogs, and through distributors including Thermo Fisher Scientific Inc., VWR and other specialized 
distributors.  We  have  sales  and  manufacturing  operations  in  the  United  States,  the  United  Kingdom,  Germany,  Sweden, 
Spain, France, Canada, and China. 

Our History  

Our business began in 1901 under the name Harvard Apparatus. It was founded by Dr. William T. Porter, a Professor 
of Physiology at Harvard Medical School and a pioneer of physiology education. We have grown over the years with the 
development and evolution of modern life science research and education. Our early inventions included ventilators based 
on Dr. Porter’s design, the mechanical syringe pump for drug infusion in the 1950s, and the microprocessor controlled syringe 
pump in the 1980s. 

In March of 1996, a group of investors acquired a majority of the then existing business of our predecessor, Harvard 
Apparatus, Inc. Following this acquisition, our focus was redirected to acquiring complimentary companies with innovative 
technologies  while  continuing  to  grow  the  existing  business  through  internal  product  development.  Since  1996,  we  have 
completed more than 26 business or product line acquisitions related to our continuing operations. We have also developed 
many new product lines including: new generation Harvard Apparatus syringe pumps, PHD Ultra series of syringe pumps, 
advanced  Inspira  ventilators,  GeneQuant  DNA/RNA/protein  calculators,  UVM  plate  readers,  BTX  Gemini  X2  multi-
waveform electroporation system, BioDrop micro-volume spectrophotometer and cuvette, OxyletPro metabolic monitoring 
system,  Multi-Channel  Systems’  automated  four  channel  PatchServer,  DP-304A  amplifiers,  Allegro  Peristaltic  pump 
systems, Centrifan small-volume evaporators and advanced VentElite ventilators. 

Led by President and CEO Jeffrey A. Duchemin, we have conducted a multi-year restructuring program to reduce costs, 
align global functions, consolidate facilities to optimize our global footprint, divest non-core businesses and to reinvest in 
key  areas  such  as  sales  and  common  IT  systems.  As  part  of  these  efforts,  we  divested  our  AHN  Biotechnologie  GmbH 
subsidiary (AHN) in the fourth quarter of 2016 and, during the first quarter of 2018, we sold substantially all the assets of our 
wholly-owned subsidiary, Denville Scientific, Inc. (Denville). 

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We  are  also  pursuing  a  strategy  to  grow  the  business  through  strategic,  accretive  acquisitions,  including  four 

acquisitions since the fourth quarter of 2014. 

Most recently, in January 2018, we acquired Data Sciences International, Inc. (DSI) for approximately $70.0 million. 
DSI, a St. Paul, Minnesota-based life science research company, is a recognized leader in physiologic monitoring focused on 
delivering preclinical products, systems, services and solutions to its customers. Its customers include pharmaceutical and 
biotechnology  companies,  as  well  as  contract  research  organizations,  academic  labs  and  government  researchers.  This 
acquisition diversifies our customer base into the biopharmaceutical and contract research organization markets and offers 
revenue and cost synergies. 

Our Strategy  

Our vision is to be a world leading life science company that excels in meeting the needs of our customers by providing 
a wide breath of innovative products and solutions, while providing exemplary customer service. Our business strategy is to 
grow our top-line and bottom-line, and build shareholder value through a commitment to: 

• 

• 

• 

• 

commercial excellence; 

new product development; 

strategic acquisitions; and 

operational efficiencies. 

Our Products  

As  of  December  31,  2017,  our  broad  core  product  range  was  organized  into  three  commercial  product  families: 
Physiology, Cell, Molecular Instruments (PCMI), Electrophysiology (Ephys), and Laboratory Products and Supplies (LPS). 
As  of  December  31,  2017,  we  primarily  sold  our  products  under  brand  names,  including  Harvard  Apparatus,  Denville 
Scientific,  KD  Scientific,  Hoefer,  Biochrom,  BTX,  Warner  Instruments,  MCS,  HEKA,  Hugo  Sachs  Elektronik,  Panlab, 
Coulbourn Instruments, TBSI, and CMA Microdialysis. Following the sale of Denville and the acquisition of DSI in 2018, 
our core broad product ranges will be organized into three commercial product families, consisting of PCMI, Ephys, and Data 
Sciences. 

Our products consist of instruments, consumables, and systems that are made up of several individual products. Sales 
prices of these products are mostly priced in the range of $5,000 to $15,000, but range from under $100 to over $100,000. 
We manufacture our products at our locations in the United States, Germany, Sweden and Spain. 

In addition to our proprietary manufactured products, we sell many products that are made by other manufacturers. 
These  distributed  products  accounted  for  approximately  36%  of  our  revenues  for  the  year  ended  December  31,  2017. 
Distributed products enable us to provide our customers with a single source for their research needs, and consist of a large 
variety  of  devices,  instruments  and  consumable  items  used  in  experiments  involving  fluid  handling,  molecular  and  cell 
biology,  tissue,  organ  and  animal  research.  Many  of  our  proprietary  manufactured  products  are  leaders  in  their  fields; 
however,  researchers  often  need  complementary  products  in  order  to  conduct  particular  experiments.  Following  is  a 
description of each product family. 

Physiology, Cell and Molecular Instruments Product Family 

Our PCMI product family includes our traditional syringe pump and peristaltic pump product lines, as well as a broad 
range of instruments and accessories for tissue, organ and animal based lab research, including surgical products, infusion 
systems,  microdialysis  instruments,  behavior  research  systems,  and  isolated  organ  and  tissue  bath  systems.  Our  product 
offerings are marketed through our Harvard Apparatus, CMA Microdialysis, Panlab, Coulbourn, Hugo Sachs brands and 
entities. We sell these products through our global sales force, technical service team and our global distribution channel. 

The  PCMI  product  family  also  includes  spectrophotometers,  microplate  readers,  amino  acid  analyzers,  gel 
electrophoresis  equipment,  and  electroporation  instruments.  We  market  them  under  the  names  Biochrom,  Libra,  WPA, 
BioDrop, Hoefer, Scie-plas, and BTX. We sell them primarily through our distribution arrangements with various distributors. 

Our PCMI product family made up approximately 56% of our global revenues for the year ended December 31, 2017. 

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Electrophysiology Family 

The  Electrophysiology  product  family  includes  the  brands  Multi-Channel  Systems,  HEKA,  TBSI  and  Warner 

Instruments. 

Multi-Channel Systems focuses on the development and manufacture of precision scientific measuring instrumentation 

and equipment in the field of electrophysiology including: 

•  Data acquisition systems, for use with custom amplifier configurations. 
•  Complete in vivo-systems, the solution for in vivo recordings with microelectrode arrays. 
•  Complete in vitro-systems for extracellular recordings from microelectrode arrays in vitro. 

HEKA also develops, designs and manufactures precision electrophysiology equipment specializing in Patch Clamp 
Amplifiers  and  both  manual  and  automated  Patch  Clamp  Systems  along  with  the  associated  software.  The  brand  also 
specializes in instrumentation and equipment for Electrochemistry. 

Warner  Instruments  manufactures  specialized  tools  for  Electrophysiology  and  Cell  Biology  research  including  cell 

chambers, perfusion controllers, temperature controllers, microincubation systems and bio-sensing systems. 

TBSI designs and develops in vivo neural interface systems research to aid neuroscience research, especially in the 
fields of electrophysiology, psychology, neurology and pharmacology. This includes both wireless and tethered systems for 
both stimulation and recording. 

Our Electrophysiology product family made up approximately 20% of our global revenues for the year ended December 

31, 2017. 

Laboratory Products and Supplies Family 

The LPS family consisted of the Denville Scientific brands. 

Denville sold laboratory products such as syringe pipettes and tips, reagents, gloves, and other equipment. As discussed 
above, during the first quarter of 2018, we sold substantially all the assets of Denville, and we shortly thereafter acquired 
Data Sciences International. As such during 2018, the Laboratory Products and Supplies Family was replaced with the Data 
Sciences product family. 

Our LPS family made up approximately 24% of our global revenues for the year ended December 31, 2017. 

Our Customers  

Our end-user customers are primarily research scientists at universities, hospitals, government laboratories, including 
the United States National Institute of Health (NIH), and pharmaceutical and biotechnology companies. We also have global 
and regional distribution partners, and original equipment manufacturer (OEM) customers who incorporate our products into 
their  products  under  their  brands.  Our  academic  customers,  which  account  for  approximately  70%  of  our  revenues 
historically, include major colleges and universities such as Baylor College of Medicine, Cambridge University, Harvard 
University, Johns Hopkins University, Massachusetts Institute of Technology, University of California system, University of 
Texas  -  MD  Anderson  Center  and  Yale  University.  Our  pharmaceutical  and  biotechnology  customers  have  included 
pharmaceutical companies and research laboratories such as Amgen, Inc., AstraZeneca plc, Genentech, Inc. and Johnson & 
Johnson. We have tens of thousands of customers worldwide and no customer accounted for more than 10% of our revenues 
in 2017. 

With  the  sale of Denville  and  the  acquisition of  DSI, both  in  January 2018,  the  percentage of our revenues  that  is 

derived from academic customers will decline from approximately 70% to closer to 60% on a pro forma basis. 

Sales and Marketing  

We  conduct  direct  sales  in  the  United  States,  the  United  Kingdom,  Germany,  France,  Spain,  Sweden,  Canada  and 
China. We sell primarily through distributors in other countries. For the year ended December 31, 2017, revenues from direct 
sales  to  end-users  represented  approximately  65%  of  our  revenues;  and  revenues  from  sales  of  our  products  through 
distributors represented approximately 35% of our revenues. 

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Direct Sales  

We have a global sales organization managing both direct sales and distributors. Our websites and catalogs serve as the 
primary sales tool for our Harvard Apparatus, Denville and other product lines, which includes both proprietary manufactured 
products  and  complementary  products  from  various  suppliers.  Our  reputation  as  a  leading  producer  of  many  of  our 
manufactured products creates traffic to our websites, enables cross-selling and facilitates the introduction of new products. 

Distributors  

We engage distributors for the sales of our own branded and private label products in certain areas of the world and for 

certain product lines. 

Research and Development 

Our principal research and development mission is to develop products that address growth opportunities within the 
life science research process, as well as to maintain and optimize our existing product portfolios. We maintain development 
staff in many of our manufacturing facilities to design and develop new products and to re-engineer existing products to bring 
them to the next generation. Our research and development expenses were approximately $5.6 million, $5.4 million and $6.4 
million for the years ended December 31, 2017, 2016 and 2015, respectively. From time to time, we receive grants from 
governmental entities in relation to research projects. Such grants received are accounted for as a reduction in research and 
development expenses over the period of the project. We anticipate that we will continue to make investments in research 
and development activities as we deem appropriate. We plan to continue to pursue a balanced development portfolio strategy 
of originating new products from internal research and acquiring products through business and technology acquisitions. 

Manufacturing  

We manufacture and test the majority of our products in our principal manufacturing facilities located in the United 
States, Sweden, Spain and Germany. We have considerable manufacturing flexibility at our various facilities, and each facility 
can  manufacture  multiple  products  at  the  same  time.  We  maintain  in-house  manufacturing  expertise,  technologies  and 
resources. We seek to maintain multiple suppliers for key components that are not manufactured in-house, and while some 
of our products are dependent on sole-source suppliers, we do not believe our dependence upon these suppliers creates any 
significant risks. 

Our  manufacturing  operations  primarily  involve  assembly  and  testing  activities  along  with  some  machine  based 

processes. 

Manufacturing Activity 

   Manufacturing Facility 

syringe pumps, ventilators, cell injectors, molecular sample preparation products, 
electroporation products, electrophysiology products, spectrophotometers, amino acid 
analysis systems, low-volume, high-throughput liquid dispensers, plate readers, 
behavioral research products, and microdialysis products 
electrophysiology products 
electrophysiology products 
electrophysiology products 
complete organ testing systems 
electrophoresis products 
behavioral research products 
behavioral research products 
microdialysis products 

Holliston, Massachusetts 

Hamden, Connecticut 
Reutlingen, Germany 
Lambrecht, Germany 

   March-Hugstetten, Germany 

Richmond, California 
Barcelona, Spain 
Durham, North Carolina 
Kista, Sweden 

Not included in the table above are the physiological monitoring products and systems that DSI manufactures at its 

leased facility in New Brighton, Minnesota. 

Going forward we will continue to evaluate our manufacturing facilities and operations to further our goal of having 

an optimal manufacturing footprint. 

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Competition  

The markets into which we sell some of our products are highly competitive, and we expect the intensity of competition 
to continue or increase. We compete with many companies engaged in developing and selling tools for life science research. 
Many of our competitors have greater financial, operational, sales and marketing resources, and more experience in research 
and development and commercialization than we have. Moreover, our competitors may have greater name recognition than 
we do, and many offer discounts as a competitive tactic. These competitors and other companies may have developed or 
could in the future develop new technologies that compete with our products, which could render our products obsolete. We 
cannot assure you that we will be able to make the enhancements to our technologies necessary to compete successfully with 
newly emerging technologies. We believe that we offer one of the broadest selections of products to organizations engaged 
in life science research. We have numerous competitors on a product line basis. We believe that we compete favorably with 
our competitors on the basis of product performance, including quality, reliability and speed, technical support, price and 
delivery time. 

We compete with several companies that provide instruments for life science research including, Lonza Group Ltd., 
Becton  Dickinson,  Eppendorf  AG,  Razel  Scientific  Instruments, Inc.,  Ugo  Basile,  Danaher  Corporation,  Bio-Rad 
Laboratories, Inc., PerkinElmer, Inc. and Thermo Fisher Scientific, Inc. 

We  cannot  forecast  if  or  when  these  or  other  companies  may  develop  competitive  products.  We  expect  that  other 
products  will  compete  with  our  products  and  potential  products  based  on  efficacy,  safety,  cost  and  intellectual  property 
positions. While we believe that these will be the primary competitive factors, other factors include, in certain instances, 
availability of supply, manufacturing, marketing and sales expertise and capability. 

Seasonality  

Sales and earnings in our third quarter are usually flat or down from the second quarter primarily because there are a 
large number of holidays and vacations during such quarter, especially in Europe. Additionally, academic institutions in the 
northern hemisphere typically take a hiatus during the summer months. Our fourth quarter revenues and earnings are often 
the highest in any fiscal year compared to the other three quarters, primarily because many of our customers tend to spend 
budgeted money before their own fiscal year ends. 

Intellectual Property  

To  establish  and protect  our  proprietary  technologies  and  products, we rely  on  a  combination of patent,  copyright, 
trademark and trade-secret laws, as well as confidentiality provisions in our contracts. Patents or patent applications cover 
certain of our new technologies. Most of our more mature product lines are protected by trade names and trade secrets only. 

We have implemented a patent strategy designed to provide us with freedom to operate and facilitate commercialization 
of  our  current  and  future  products.  Our  success  depends,  to  a  significant  degree,  upon  our  ability  to  develop  proprietary 
products and technologies. We intend to continue to file patent applications as we develop new products and technologies. 

Patents provide some degree of protection for our intellectual property. However, the assertion of patent protection 
involves complex legal and factual determinations and is therefore uncertain. The scope of any of our issued patents may not 
be  sufficiently  broad  to  offer  meaningful  protection.  In  addition,  our  issued  patents  or  patents  licensed  to  us  may  be 
successfully challenged, invalidated, circumvented or unenforceable so that our patent rights would not create an effective 
competitive barrier. Moreover, the laws of some foreign countries may protect our proprietary rights to a greater or lesser 
extent  than  the  laws  of  the  United  States.  In  addition,  the  laws  governing  patentability  and  the  scope  of  patent  coverage 
continue to evolve, particularly in areas of interest to us. As a result, there can be no assurance that patents will be issued 
from any of our patent applications or from applications licensed to us. As a result of these factors, our intellectual property 
positions bear some degree of uncertainty. 

We also rely in part on trade-secret protection of our intellectual property. We attempt to protect our trade secrets by 
entering into confidentiality agreements with third parties, employees and consultants. Our employees and consultants also 
sign  agreements  requiring  that  they  assign  to  us  their  interests  in  patents  and  copyrights  arising  from  their  work  for  us. 
Although  many  of  our  United  States  employees  have  signed  agreements  not  to  compete  unfairly  with  us  during  their 
employment and after termination of their employment, through the misuse of confidential information, soliciting employees, 
soliciting customers and the like, the enforceability of these provisions varies from jurisdiction to jurisdiction and, in some 
circumstances, they may not be enforceable. In addition, it is possible that these agreements may be breached or invalidated 
and  if so,  there  may  not  be an  adequate  corrective  remedy  available. Despite  the  measures  we have  taken  to protect  our 
intellectual  property,  we  cannot  assure  you  that  third  parties  will  not  independently  discover  or  invent  competing 

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technologies, or reverse engineer our trade secrets or other technologies. Therefore, the measures we are taking to protect our 
proprietary rights may not be adequate. 

We do not believe that our products infringe on the intellectual property rights of any third party. We cannot assure 
you, however,  that  third parties  will  not  claim  such  infringement  by  us  or our  licensors  with respect  to  current  or future 
products.  We  expect  that  product  developers  in  our  market  will  increasingly  be  subject  to  such  claims  as  the  number  of 
products and competitors in our market segment grows and the product functionality in different market segments overlaps. 
In addition, patents on production and business methods are becoming more common and we expect that more patents will 
be issued in our technical field. Any such claims, with or without merit, could be time-consuming, result in costly litigation 
and diversion of management’s attention and resources, cause product shipment delays or require us to enter into royalty or 
licensing agreements. Moreover, such royalty or licensing agreements, if required, may not be on terms advantageous to us, 
or acceptable at all, which could seriously harm our business or financial condition. 

“Harvard” is a registered trademark of Harvard University. The marks “Harvard Apparatus” and “Harvard Bioscience” 

are being used pursuant to a license agreement entered into in December 2002 between us and Harvard University. 

Government Regulation  

We  are  not  subject  to  direct  governmental  regulation  other  than  the  laws  and  regulations  generally  applicable  to 
businesses in the domestic and foreign jurisdictions in which we operate. In particular, our current products are not subject 
to pre-market approval by the United States Food and Drug Administration (FDA) for use on human clinical patients. In 
addition, we believe we are currently in compliance with all relevant environmental laws. 

Employees 

As  of  December  31,  2017,  we  employed  434  employees,  of  which  413  are  full-time  and  21  are  part-time.  As  of 

December 31, 2016, we employed 435 employees, of which 411 were full-time and 24 were part-time. 

Geographical residence information for these employees is summarized in the table below: 

As of December 31, 2017 

United States .................................................................................................................................................     
Germany ........................................................................................................................................................     
United Kingdom ............................................................................................................................................     
Spain ..............................................................................................................................................................     
Canada ...........................................................................................................................................................     
Sweden ..........................................................................................................................................................     
China .............................................................................................................................................................     
France ............................................................................................................................................................     
Total ..............................................................................................................................................................     

245   
93   
46   
27   
7   
6   
8   
2   
434   

Included in the table above are 55 Denville employees. All Denville employees were U.S. based as of December 31, 
2017. Not included in the table above are employees of DSI and its subsidiaries, which had approximately 180 employees at 
the end of 2017. 

Geographic Area  

Financial  information  regarding  geographic  areas  in  which  we  operate  is  provided  in  Note  21  of  the  “Notes  to 

Consolidated Financial Statements,” which are included elsewhere in this Annual Report. 

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Executive Officers of the Registrant 

The following table shows information about our executive officers as of December 31, 2017. 

Name 
Jeffrey Duchemin .................... 
Robert Gagnon ........................ 
Yong Sun ................................. 

Age 
52 
43 
54 

Position 
Chief Executive Officer, President and Director 
Chief Financial Officer 
Vice President, Commercial Operations 

Jeffrey A. Duchemin was appointed Chief Executive Officer on August 26, 2013.  He assumed the additional roles of 
President on November 1, 2013 and Director on October 29, 2013. Prior to joining Harvard Bioscience, Mr. Duchemin spent 
16 years with Becton Dickinson (BD) in progressive sales, marketing and executive leadership positions across BD’s three 
business segments; BD Medical Systems, BD Diagnostic Systems, and BD Biosciences. In October 2012, BD Biosciences 
Discovery Labware was acquired by Corning Life Sciences. Mr. Duchemin was a Global Business Director for Corning Life 
Sciences until his departure to Harvard Bioscience. Mr. Duchemin is a transformational leader with demonstrated business 
results. The depth of his experience spans across a broad range of life science research and medical device products resulting 
in  growth  on  a  global  basis.  Mr.  Duchemin  earned  an  M.B.A.  from  Southern  New  Hampshire  University  and  a  B.S.  in 
accounting from the University of Massachusetts Dartmouth. 

Robert E. Gagnon was appointed Chief Financial Officer on November 1, 2013.  Prior to joining the company he was 
recently  Executive  Vice  President,  Chief Financial Officer  and  Treasurer  at  Clean Harbors, Inc. (NYSE:CLH),  a  leading 
provider of environmental, energy and industrial services throughout North America. Prior to this, he served in progressive 
executive  positions  at  Biogen  Idec,  Inc.,  a  Fortune  500  company  developing  treatments  in  the  areas  of  immunology  and 
neurology. Earlier, he worked in a variety of senior positions at Deloitte & Touche, LLP, and PricewaterhouseCoopers, LLP. 
Mr. Gagnon holds an M.B.A. from the MIT Sloan School of Management and a B.A. in accounting from Bentley College. 

Yong Sun assumed the role of Vice President, Commercial Operations on October 28, 2015. Previously Mr. Sun held 
the position of Vice President, Strategic Marketing and Business Development and Vice President, R&D since October 28, 
2013 and March 10, 2014, respectively. Prior to joining Harvard Bioscience, he served as Vice President of Global Marketing 
and Americas Sales at Beaver-Visitec International, a company combining former ophthalmic business units from BD and 
Medtronic; in this role he led global marketing to develop and implement strategic marketing plans in target surgical markets. 
Prior to this, he served in progressive positions at BD, including Director of Global Marketing & United States Sales. Earlier, 
he served as Marketing Manager, Global Life Sciences Market & Greater China Region at Eli Lilly & Company’s eLilly Unit 
(now InnoCentive, Inc.). Mr. Sun, holds an M.B.A. from the MIT Sloan School of Management, a M.S. in environmental 
science & engineering from Northeastern University and a B.S. in biochemistry from Peking University. 

Available Information and Website  

Our  website  address  is  www.harvardbioscience.com.  Our  Annual  Report  on  Form 10-K,  Quarterly  Reports  on 
Form 10-Q, Current Reports on Form 8-K, and exhibits and amendments to those reports filed or furnished with the Securities 
and Exchange Commission pursuant to Section 13(a) of the Exchange Act are available for review on our website and the 
Securities and Exchange Commission’s website at www.sec.gov. Any such materials that we file with, or furnish to, the SEC 
in the future will be available on our website as soon as reasonably practicable after they are electronically filed with, or 
furnished to, the SEC. The information on our website is not incorporated by reference into this Annual Report on Form 10-
K. 

Item 1A. 

Risk Factors.  

The following factors should be reviewed carefully, in conjunction with the other information contained in this Annual 
Report  on  Form  10-K.  As  previously  discussed,  our  actual  results  could  differ  materially  from  our  forward-looking 
statements. Our business faces a variety of risks. These risks include those described below and may include additional risks 
and uncertainties not presently known to us or that we currently deem immaterial. If any of the events or circumstances 
described  in  the  following  risk  factors  occur,  our  business  operations,  performance  and  financial  condition  could  be 
adversely affected and the trading price of our common stock could decline.  

Reductions in customers’ research budgets or government funding may adversely affect our business. 

Many  of  our  customers  representing  a  significant  portion  of  our  revenues  are  universities,  government  research 
laboratories, private foundations and other institutions who are dependent for their funding upon grants from U.S. government 
agencies, such as the United States National Institutes of Health (NIH), and similar agencies in other countries. Research and 

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development spending of our customers can fluctuate based on spending priorities and general economic conditions. The 
level of government funding of research and development is unpredictable. There have been instances where NIH grants have 
been  frozen  or  otherwise  unavailable  for  extended  periods  or  directed  for  certain  products.  Any  reduction  or  delay  in 
governmental  spending  could  cause  our  customers  to  delay  or  forego  purchases  of  our  products.  If  government  funding 
necessary to purchase our products were to decrease, our business and results of operations could be materially adversely 
affected. Spending by some of these customers fluctuates based on budget allocations and the timely passage of the annual 
federal budget. An impasse in federal government budget decisions could lead to substantial delays or reductions in federal 
spending. 

With respect to acquisitions we have completed or may seek to consummate in the future, we have and will incur a variety 
of  costs,  and  may  never  realize  the  anticipated  benefits  of  the  acquisitions  due  in  part  to  difficulties  integrating  the 
businesses, operations and product lines.  

Our business strategy includes the acquisition of businesses, technologies, services or products that we believe are a 
strategic fit with our business. Most recently, in January 2018, we completed the acquisition of all the outstanding stock of 
Data  Sciences  International,  Inc.,  (DSI)  a  privately  held  physiologic  monitoring  business  with  headquarters  in  St.  Paul, 
Minnesota. With respect to these recent acquisitions or if we undertake any future acquisition, the process of integrating the 
acquired business, technology, service or product may result in unforeseen operating difficulties and expenditures and may 
absorb  significant  management  attention  that  would  otherwise  be  available  for  ongoing  development  of  our  business. 
Moreover, we may fail to realize the anticipated benefits of any acquisition as rapidly as expected or at all. Such transactions 
are inherently risky, and any such recent or future acquisitions could reduce stockholders’ ownership, cause us to incur debt, 
expose us to future liabilities and result in amortization expenses related to intangible assets with definite lives, which may 
adversely impact our ability to undertake future acquisitions on substantially similar terms. We may also incur significant 
expenditures in anticipation of an acquisition that is never realized. 

Our  ability  to achieve  the benefits  of acquisitions  depends  in part  on  the  integration  and  leveraging of  technology, 
operations, sales and marketing channels and personnel. The integration process is a complex, time-consuming and expensive 
process and may disrupt our business if not completed in a timely and efficient manner. We may have difficulty successfully 
integrating acquired businesses, and their domestic and foreign operations or product lines, and as a result, we may not realize 
any of the anticipated benefits of the acquisitions we make. We cannot assure that our growth rate will equal the growth rates 
that have been experienced by us and these and other acquired companies, respectively, operating as separate companies in 
the past. 

We have substantial debt and other financial obligations and we may incur even more debt. Any failure to meet our debt 
and other financial obligations could harm our business, financial condition and results of operations.  

We have substantial debt and other financial obligations and significant unused borrowing capacity. On January 31, 
2018,  we  entered  into  a  Financing  Agreement  with  Cerberus  Business  Finance,  LLC,  as  agent  and  lender  (the  Credit 
Agreement). As of March 16, 2018, we had borrowings of $67.0 million under the Credit Agreement. The Credit Agreement 
includes  financial  covenants  relating  to  leverage  and  fixed  charges,  as  well  as  other  customary  affirmative  and  negative 
covenants, including limitations on our ability to incur additional indebtedness and requires lender approval for acquisitions 
funded with cash, promissory notes and/or other consideration in excess of $1.0 million and for acquisitions in excess of $0.5 
million. If we are not in compliance with certain of these covenants, in addition to other actions the creditor may require, the 
amounts outstanding under the Credit Agreement may become immediately due and payable. This immediate payment may 
negatively impact our financial condition. In addition, any failure to make scheduled payments of interest and principal on 
our outstanding indebtedness would likely harm our ability to incur additional indebtedness on acceptable terms. Our cash 
flow and capital resources may be insufficient to pay interest and principal on our debt in the future. If that should occur, our 
capital  raising  or  debt  restructuring  measures  may  be  unsuccessful  or  inadequate  to  meet  our  scheduled  debt  service 
obligations, which could cause us to default on our obligations and further impair our liquidity. 

The  obligations  under  the  Credit  Agreement  and  related  guarantees  are  secured  on  a  first-priority  basis  (subject  to 
certain liens permitted under the Credit Agreement) by a lien on substantially all the tangible and intangible assets of our 
company and the subsidiary guarantors, including all of the capital stock held by such obligors, subject to a 65% limitation 
on pledges of capital stock of foreign subsidiaries and certain other exceptions. Our Credit Agreement and related obligations: 

•  Require us to dedicate significant cash flow to the payment of principal and interest on our debt, which reduces the 

funds we have available for other purposes; 

•  May limit our flexibility in planning for or reacting to changes in our business and market conditions or funding our

strategic growth plan; 

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• 

Impose on us additional financial and operational restrictions; 

•  Expose us to interest rate risk since a portion of our debt obligations is at variable rates (which is mitigated to a
certain extent, by interest rate hedging transactions we entered into in connection with our Credit Agreement); and 

•  Restrict our ability to fund certain acquisitions. 

In addition, investors may be apprehensive about investing in companies such as ours that carry a substantial amount 

of leverage on their balance sheets, and this apprehension may adversely affect the price of our common stock. 

Further, based upon our actual performance levels, our covenants relating to leverage and fixed charges could limit our 

ability to incur additional debt, which could hinder our ability to execute our current business strategy. 

Our  ability  to  make  scheduled  payments  on  our  debt  and  other  financial  obligations  and  comply  with  financial 
covenants depends on our financial and operating performance. Our financial and operating performance will continue to be 
subject to prevailing economic conditions and to financial, business and other factors, some of which are beyond our control. 
Failure within any applicable grace or cure periods to may such payments, comply with the financial covenants, or any other 
non-financial or restrictive covenant, would create a default under our Credit Agreement. The maturity date with respect to 
the loans under the Credit Agreement is currently January 31, 2023. Our cash flow and existing capital resources may be 
insufficient to repay our debt at maturity, in which such case prior thereto we would have to extend such maturity date, or 
otherwise repay, refinance and or restructure the obligations under the Credit Agreement, including with proceeds from the 
sale of assets, and additional equity or debt capital. If we are unsuccessful in obtaining such extension, or entering into such 
repayment, refinance or restructure prior to maturity, or any other default existed under the Credit Agreement, our lenders 
could accelerate the indebtedness under the Credit Agreement, foreclose against their collateral or seek other remedies, which 
would jeopardize our ability to continue our current operations. 

A portion of our revenues are derived from customers from the pharmaceutical and biotechnology industries and are 
subject to risks faced by those industries. Such risks may adversely affect our financial results.  

We derive a significant portion of our revenues from pharmaceutical and biotechnology companies. We expect that 
pharmaceutical and biotechnology companies will continue to be a significant source of our revenues for the foreseeable 
future, including in our PCMI, Ephys and Data Sciences commercial product families. As a result, we are subject to risks and 
uncertainties  that  affect  the  pharmaceutical  and  biotechnology  industries,  such  as  government  regulation,  ongoing 
consolidation, uncertainty of technological change, and reductions and delays in research and development expenditures by 
companies in these industries. 

In particular, the biotechnology industry is largely dependent on raising capital to fund its operations. If biotechnology 
companies that are our customers are unable to obtain the financing necessary to purchase our products, our business and 
results of operations could be adversely affected. In addition, we are dependent, both directly and indirectly, upon general 
health care spending patterns, particularly in the research and development budgets of the pharmaceutical and biotechnology 
industries, as well as upon the financial condition and purchasing patterns of various governments and government agencies. 
As it relates to both the biotechnology and pharmaceutical industries, many companies have significant patents that have 
expired  or  are  about  to  expire,  which  could  result  in  reduced  revenues  for  those  companies.  If  pharmaceutical  or 
biotechnology companies that are our customers suffer reduced revenues as a result of these patent expirations, they may be 
unable to purchase our products, and our business and results of operations could be adversely affected. 

Customer, vendor and employee uncertainty about the effects of any of our acquisitions could harm us.  

The  customers  of  any  company  we  acquire,  including  DSI  and  others  in  the  future,  may,  in  response  to  the 
consummation  of  the  acquisition,  delay  or  defer  purchasing  decisions.  Any  delay  or  deferral  in  purchasing  decisions  by 
customers could adversely affect our business. Similarly, employees of acquired companies may experience uncertainty about 
their future role until or after we execute our post-acquisition strategies. This may adversely affect our ability to attract and 
retain key management, sales, marketing and technical personnel following an acquisition. 

Our business is subject to economic, political and other risks associated with international revenues and operations.  

We manufacture and sell our products worldwide and as a result, our business is subject to risks associated with doing 
business internationally. A substantial amount of our revenues are derived from international operations, and we anticipate 
that a significant portion of our sales will continue to come from outside the United States in the future. We anticipate that 
revenues from international operations will likely continue to increase as a result of our efforts to expand our business in 

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markets abroad. In addition, a number of our manufacturing facilities and suppliers are located outside the United States. Our 
foreign operations subject us to certain risks, including: effects of fluctuations in foreign currency exchange rates (discussed 
below); the impact of local economic conditions; local product preferences and seasonality (discussed below) and product 
requirements;  local  difficulty  to  effectively  establish  and  expand  our  business  and  operations  in  international  markets; 
disruptions of capital and trading markets; restrictions and potentially negative tax implications of transfer of capital across 
borders; differing labor regulations; other factors beyond our control, including potential political instability, terrorism, acts 
of war, natural disasters and diseases; unexpected changes and increased enforcement of regulatory requirements and various 
state,  federal  and  international,  intellectual  property,  environmental,  antitrust,  anti-corruption,  fraud  and  abuse (including 
anti-kickback and false claims laws) and employment laws; and interruption to transportation flows for delivery of parts to 
us and finished goods to our customers. 

Specifically with respect to the expansion of our business into China, our financial performance may be subject to the 
following risks, among others affecting companies that operate in China: the impact of declining economic growth in China; 
regulation  of  foreign  investment  and  business  activities  by  the  Chinese  government,  including  recent  scrutiny  of  foreign 
companies, may limit our ability to expand our business in China; uncertainties with respect to the legal system in China may 
limit the legal protections available to us in China; government restrictions on the remittance of currency out of China and 
the ability of any subsidiary we may establish in China to pay dividends and make other distributions to us; and potential 
unfavorable tax consequences as a result of our operations in China. 

Newly enacted U.S. government tax reform could have a negative impact on the results of future operations. 

On December 22, 2017, the President of the United States signed into law H.R. 1, originally known as the “Tax Cuts 
and Jobs Act”, hereafter referred to as “the Tax Act”, to be effective as of January 1, 2018. The Company is in the process of 
determining the impact to the financial statements of all aspects of the Tax Act and will reflect the impact of such reform in 
the financial statements during the period in which such amounts can be reasonably estimated. The Tax Act contained certain 
substantial changes to the Internal Revenue Code, some of which could have an adverse effect on our business. The Tax Act 
significantly revises the U.S. corporate income tax by, among other things, lowering corporate income tax rates, implementing 
a modified territorial tax system and imposing a repatriation tax on undistributed foreign earnings of foreign subsidiaries. 
Given the complexity of the Tax Act, anticipated guidance from the Internal Revenue Service about implementing the Tax 
Act, and the potential for additional guidance from the Securities and Exchange Commission or the Financial Accounting 
Standards Board related to the Tax Act, the intended and unintended consequences of the Tax Act on our business and on 
holders  of  our  common  shares  is  uncertain  and  could  be  adverse,  which  could  result  in  further  impact  to  our  results  of 
operations, financial condition and cash flow. 

Foreign currency exchange rate fluctuations may have a negative impact on our reported earnings.  

We are also subject to the risks of fluctuating foreign currency exchange rates, which could have an adverse effect on 
the sales price of our products in foreign markets, as well as the costs and expenses of our foreign subsidiaries. A substantial 
amount of our revenues are derived from international operations, and we anticipate that a significant portion of revenues 
will continue to come from outside the United States in the future. As a result, currency fluctuations among the United States 
dollar, British pound, euro and the other currencies in which we do business have caused and will continue to cause foreign 
currency translation and transaction gains and losses. We have not used forward exchange contracts to hedge our foreign 
currency exposures. We attempt to manage foreign currency risk through the matching of assets and liabilities. In the future, 
we  may  undertake  to  manage  foreign  currency  risk  through  hedging  methods,  including  foreign  currency  contracts.  We 
recognize foreign currency gains or losses arising from our operations in the period incurred. We cannot guarantee that we 
will be successful in managing foreign currency risk or in predicting the effects of exchange rate fluctuations upon our future 
operating results because of the number of currencies involved, the variability of currency exposure and the potential volatility 
of currency exchange rates. We cannot predict with any certainty changes in foreign currency exchange rates or the degree 
to which we can address these risks. 

Economic conditions and regulatory changes caused by the United Kingdom’s likely exit from the European Union could 
adversely affect our business. 

In June 2016, the United Kingdom (the U.K.) held a referendum in which voters approved an exit from the European 
Union (E.U.), commonly referred to as Brexit. On March 29, 2017, the U.K. formally notified the E.U. of its intention to 
withdraw pursuant to the Treaty on European Union. The withdrawal of the U.K. from the E.U. will take effect either when 
agreed upon or, in the absence of such an agreement, two years after the U.K. provided its notice of withdrawal. It appears 
likely that this withdrawal will involve a process of lengthy negotiations between the U.K. and the E.U. member states to 
determine the terms of the withdrawal as well as the U.K.’s relationship with the E.U. going forward. The announcement of 
Brexit has resulted in significant volatility in global stock market and currency exchange rate fluctuations that resulted in 

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strengthening of the U.S. dollar relative to other foreign currencies in which we conduct business. The announcement of 
Brexit  and  the  likely  withdrawal  of  the  U.K.  from  the  E.U.  may  also  create  global  economic  uncertainty,  including  an 
uncertain funding environment for U.K. customers receiving funding from the E.U, which may cause our customers to closely 
monitor their costs and reduce their spending budgets. The effects of Brexit will depend on any agreements the U.K. makes 
to retain access to E.U. markets either during a transitional period or more permanently. Since a significant proportion of the 
regulatory framework in the U.K. is derived from E.U. directives and regulations, the referendum could materially change 
the regulatory regime applicable to the approval of any product candidates in the U.K. In addition, since the EMA is located 
in the U.K., the implications for the regulatory review process in the E.U. has not been clarified and could result in relocation 
of the EMA or a disruption in the EMA review process. 

Further, Brexit could adversely affect European and worldwide economic or market conditions and could contribute to 
instability in global financial markets. Brexit is likely to lead to legal uncertainty and potentially divergent national laws and 
regulations as the U.K. determines which E.U. laws to replace or replicate. This could adversely affect our business, financial 
condition, operating results and cash flows. 

Domestic and global economic conditions could adversely affect our operations. 

We  are  subject  to  the  risks  arising  from  adverse  changes  in  domestic  and  global  economic  conditions.  If  global 
economic and market conditions, or economic conditions in the United States, deteriorate, we may experience an adverse 
effect  on  our  business,  operating  results  and  financial  condition.  Concerns  about  credit  markets,  consumer  confidence, 
economic conditions, government spending to sponsor life science research, volatile corporate profits and reduced capital 
spending could negatively impact demand for our products. If economic growth in the United States and other countries slows 
or deteriorates, customers may delay or forego purchases of our products. Unstable economic, political and social conditions 
make it difficult for our customers, our suppliers and us to accurately forecast and plan future business activities. If such 
conditions exist, our business, financial condition and results of operations could suffer. We cannot project the extent of the 
impact of the economic environment on our industry or us. 

Changes in governmental regulations may reduce demand for our products, adversely impact our revenues, or increase 
our expenses.  

We compete in many markets in which we and our customers must comply with federal, state, local and international 
regulations. We  develop,  configure  and  market our products  to  meet  customer  needs  created by  those  regulations.  These 
requirements include, among other things, regulations regarding manufacturing practices, product labeling, and advertising 
and post marketing reporting. We must incur expense and spend time and effort to ensure compliance with these complex 
regulations. Possible regulatory actions for non-compliance could include warning letters, fines, damages, injunctions, civil 
penalties,  recalls,  seizures  of  our  products,  and  criminal  prosecution.  These  actions  could  result  in,  among  other  things, 
substantial modifications to our business practices and operations; refunds, recalls, or seizures of our products; a total or 
partial shutdown of production in one or more of our facilities while we or our suppliers remedy the alleged violation; and 
withdrawals or suspensions of current products from the market. Any of these events could disrupt our business and have a 
material adverse effect on our revenues, profitability and financial condition. 

We continue to expand our business into foreign countries and international markets. If our products are not accepted in 
these new markets our financial performance may suffer.  

We continue to aggressively expand our sales and marketing efforts in foreign countries and international markets. The 
cost and diversion of resources to these efforts may not result in an increase in revenues in our business. Expansion of our 
business into new markets may be more costly and require the devotion of more of our management’s time than we anticipate, 
which may hurt our business performance in other markets. Our operating results may suffer to the extent that our efforts to 
expand our product sales in these new markets are delayed or prove to be unsuccessful. 

The life sciences industry is very competitive. 

We expect to encounter increased competition from both established and development-stage companies that continually 
enter the market. These include companies developing and marketing life science instruments, systems and lab consumables, 
health  care  companies  that  manufacture  laboratory-based  tests  and  analyzers,  diagnostic  and  pharmaceutical  companies, 
analytical  instrument  companies,  and  companies  developing  life  science  or  drug  discovery  technologies.  Currently,  our 
principal competition comes from established companies that provide products that perform many of the same functions for 
which  we  market  our  products.  Many  of  our  competitors  have  substantially  greater  financial,  operational,  marketing  and 
technical resources than we do. Moreover, these competitors may offer broader product lines and tactical discounts, and may 
have greater name recognition. In addition, we may face competition from new entrants into the field. We may not have the 

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financial resources, technical expertise or marketing, distribution or support capabilities to compete successfully in the future. 
In  addition,  we  face  changing  customer  preferences  and  requirements,  including  increased  customer  demand  for  more 
environmentally-friendly products. 

The  life sciences  industry  is also  subject  to  rapid  technological  change and discovery.  The development  of new  or 
improved products, processes or technologies by other companies may render our products or proposed products obsolete or 
less competitive. In some instances, our competitors may develop or market products that are more effective or commercially 
attractive than our current or future products. To meet the evolving needs of customers, we must continually enhance our 
current and planned products and develop and introduce new products. However, we may experience difficulties that may 
delay  or  prevent  the  successful  development,  introduction  and  marketing  of  new  products  or  product  enhancements.  In 
addition, our product lines are based on complex technologies that are subject to change as new technologies are developed 
and introduced in the marketplace. We may have difficulty in keeping abreast of the changes affecting each of the different 
markets we serve or intend to serve. Our failure to develop and introduce products in a timely manner in response to changing 
technology, market demands or the requirements of our customers could cause our product sales to decline, and we could 
experience significant losses. 

We offer and plan to offer a broad range of products and have incurred and expect to continue to incur substantial 
expenses for development of new products and enhanced versions of our existing products. The speed of technological change 
in our market may prevent us from being able to successfully market some or all of our products for the length of time required 
to  recover  development  costs.  Failure  to  recover  the  development  costs  of  one  or  more  products  or  product  lines  could 
decrease our profitability or cause us to experience significant losses. 

Ethical concerns surrounding the use of our products and misunderstanding of the nature of our business could adversely 
affect our ability to develop and sell our existing products and new products.  

Some of our products may be used in areas of research usage involving animal research and other techniques presently 
being explored in the life science industry. These techniques have drawn negative attention in the public forum. Government 
authorities may regulate or prohibit any of these activities. Additionally, the public may disfavor or reject these activities. 

If we are not able to manage our growth, our operating profits may be adversely impacted.  

Our success will depend on the expansion of our operations through both organic growth and acquisitions. Effective 
growth  management  will  place  increased  demands  on  our  management  team,  operational  and  financial  resources  and 
expertise. To manage growth, we must expand our facilities, optimize our operational, financial and management systems, 
and hire and train additional qualified personnel. Failure to manage this growth effectively could impair our ability to generate 
revenues  or  could  cause  our  expenses  to  increase  more  rapidly  than  revenues,  resulting  in  operating  losses  or  reduced 
profitability. 

Failure or inadequacy of our information technology infrastructure or software could adversely affect our day-to-day 
operations and decision-making processes and have an adverse effect on our performance. 

We depend on accurate and timely information and numerical data from key software applications to aid our day-to-
day  business,  financial  reporting  and  decision-making  and,  in  many  cases,  proprietary  and  custom-designed  software  is 
necessary to operate our business. We are upgrading our disaster recovery procedures for our critical systems. However, any 
disruption  caused  by  the  failure  of  these  systems,  the  underlying  equipment,  or  communication  networks  could  delay  or 
otherwise adversely impact our day-to-day business and decision making, could make it impossible for us to operate critical 
equipment, and could have an adverse effect on our performance, if our disaster recovery plans do not mitigate the disruption. 
Disruptions could be caused by a variety of factors, such as catastrophic events or weather, power outages, or cyber-attacks 
on our systems by outside parties. 

An  information  security  incident,  including  a  cybersecurity  breach,  could  have  a  negative  impact  to  our  business  or 
reputation 

To meet business objectives, we rely on both internal information technology (IT) systems and networks, and those of 
third parties and their vendors, to process and store sensitive data, including confidential research, business plans, financial 
information,  intellectual  property,  and  personal  data  that  may  be  subject  to  legal  protection.  The  extensive  information 
security and cybersecurity threats, which affect companies globally, pose a risk to the security and availability of these IT 
systems and networks, and the confidentiality, integrity, and availability of our sensitive data. We continually assess these 
threats and make investments to increase internal protection, detection, and response capabilities, as well as ensure our third 
party providers have required capabilities and controls, to address this risk. To date, we have not experienced any material 

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impact to the business or operations resulting from information or cybersecurity attacks; however, because of the frequently 
changing attack techniques, along with the increased volume and sophistication of the attacks, there is the potential for us to 
be adversely impacted. This impact could result in reputational, competitive, operational or other business harm as well as 
financial costs and regulatory action. 

We may experience difficulties fully implementing our enterprise resource planning systems.  

We have been engaged in a project to upgrade and harmonize our enterprise resource planning (ERP) systems. Our 
ERP  systems  are  critical  to  our  ability  to  accurately  maintain  books  and  records,  record  transactions,  provide  important 
information  to  our  management  and  prepare  our  financial  statements.  The  implementation  of  the  new  ERP  systems  has 
required, and will continue to require, the investment of significant financial and human resources. In addition, we may not 
be  able  to  successfully  complete  the  full  implementation  of  the  ERP  systems  without  experiencing  difficulties.  Any 
disruptions, delays or deficiencies in the design and implementation of the new ERP systems could adversely affect our ability 
to process orders, ship products, provide services and customer support, send invoices and track payments, fulfill contractual 
obligations or otherwise operate our business. 

We  may  incur  additional  restructuring  costs  or  not  realize  the  expected  benefits of our  initiatives  to  reduce operating 
expenses to date and in the future.  

We may not be able to implement all of the actions that we intend to take in the restructuring of our operations and we 
may  not  be  able  to  fully  realize  the  expected  benefits  from  such  realignment  and  restructuring  plans  or  other  similar 
restructurings in the future. In addition, we may incur additional restructuring costs in implementing such realignment and 
restructuring plans or other similar future plans in excess of our expectations. The implementation of our restructuring efforts, 
including the reduction of our workforce, may not improve our operational and cost structure or result in greater efficiency 
of  our  organization;  and  we  may  not  be  able  to  support  sustainable  revenue  growth  and  profitability  following  such 
restructurings. 

Attractive acquisition opportunities may not be available to us in the future.  

We  will  consider  the  acquisition  of other businesses. However, we  may  not  have  the  opportunity  to  make  suitable 
acquisitions on favorable terms in the future, which could negatively impact the growth of our business. In order to pursue 
such opportunities, we may require significant additional financing, which may not be available to us on favorable terms, if 
at all. We expect that our competitors, many of which have significantly greater resources than we do, will compete with us 
to acquire businesses. This competition could increase prices for acquisitions that we would likely pursue. 

We may be the subject of lawsuits from counterparties to acquisitions and divestitures, including an acquiring company 
or  its  stockholders,  an  acquired  company’s  previous  stockholders,  a  divested  company’s  stockholders  or  our  current 
stockholders.  

We  may  be  the  subject  of  lawsuits  from  either  an  acquiring  company  or  its  stockholders,  an  acquired  company’s 
previous stockholders, a divested company’s stockholders or our current stockholders. Such lawsuits could result from the 
actions  of  the  acquisition  or  divestiture  target  prior  to  the  date  of  the  acquisition  or  divestiture,  from  the  acquisition  or 
divestiture transaction itself or from actions after the acquisition or divestiture. Defending potential lawsuits could cost us 
significant expense and detract management’s attention from the operation of the business. Additionally, these lawsuits could 
result in the cancellation of or the inability to renew certain insurance coverage that would be necessary to protect our assets. 

Failure  to  raise  additional  capital  or  generate  the  significant  capital  necessary  to  implement  our  acquisition  strategy, 
expand our operations and invest in new products could reduce our ability to compete and result in less revenues.  

We anticipate that our financial resources, which include available cash, cash generated from operations, and debt and 
equity capacity, will be sufficient to finance operations and capital expenditures for at least the next twelve months. However, 
this expectation is premised on the current operating plan, which may change as a result of many factors, including market 
acceptance  of  new  products  and  future  opportunities  with  collaborators.  Consequently,  we  may  need  additional  funding 
sooner than anticipated. In addition, our Credit Agreement is not sufficient to fund our acquisition strategy. In such case, our 
inability to raise sufficient capital on favorable terms and in a timely manner (if at all) could seriously harm our business, 
product development, and acquisition efforts. In addition, our Credit Agreement contains limitations on our ability to incur 
additional  indebtedness  and  requires  lender  approval  for  acquisitions  funded  with  cash,  promissory  notes  and/or  other 
consideration in excess of $1.0 million and for acquisitions in excess of $0.5 million. If future financing is not available or is 
not available on acceptable terms, we may have to alter our operations or change our business strategy. We cannot assure you 
that the capital required to fund operations or our acquisition strategy will be available in the future. 

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If we raise additional funds through the sale of equity or convertible debt or equity-linked securities, existing percentages 
of ownership in our common stock will be reduced and these transactions may dilute the value of our outstanding common 
stock. 

We may raise additional funds through the sale of equity or convertible debt or equity-linked securities to repay our 
existing indebtedness, implement our acquisition strategy, expand our operations and/or invest in new products. If we so raise 
additional  funds  through  such  sales,  existing  percentages  of  ownership  in  our  common  stock  will  be  reduced  and  these 
transactions may dilute the value of our outstanding common stock. We may issue securities that have rights, preferences and 
privileges senior to our common stock. If we raise additional funds through collaborations or licensing arrangements, we may 
relinquish rights to certain of our technologies or products, or grant licenses to third parties on terms that are unfavorable. 

Our stock price has fluctuated in the past and could experience substantial declines in the future.  

The market price of our common stock has experienced significant fluctuations and may become volatile and could 

decline in the future, perhaps substantially, in response to various factors including, but not limited to: 

•  Significant sales of our common stock, whether by us or our shareholders; 

•  volatility of the financial markets; 

•  uncertainty regarding the prospects of the domestic and foreign economies; 

• 

• 

technological innovations by competitors or in competing technologies; 

revenues and operating results fluctuating or failing to meet the expectations of management, securities analysts, or
investors in any quarter; 

•  comments  of  securities  analysts  and  mistakes  by  or  misinterpretation  of  comments  from  analysts,  downward

revisions in securities analysts’ estimates or management guidance; 

• 

investment banks and securities analysts becoming subject to lawsuits that may adversely affect the perception of 
the market; 

•  conditions or trends in the biotechnology and pharmaceutical industries; 

•  announcements of significant acquisitions or financings or strategic partnerships; 

• 

failure to realize the anticipated benefits of the DSI acquisition; 

•  non-compliance with the internal control standards pursuant to the Sarbanes-Oxley Act of 2002; and 

•  a decrease in the demand for our common stock. 

In  addition,  public  stock  markets  have  experienced  extreme  price  and  trading  volatility.  The  stock  market  and  the 
NASDAQ Global Market in general, and the biotechnology industry and small cap markets in particular, have experienced 
significant  price  and  volume  fluctuations  that  at  times  may  have  been  unrelated  or  disproportionate  to  the  operating 
performance of those companies. These broad market and industry factors may further harm the market price of our common 
stock, regardless of our operating performance. In the past, securities class action litigation has often been instituted following 
periods of volatility in the market price of a company’s securities. A securities class action suit against us could result in 
substantial costs, potential liabilities and the diversion of management’s attention and resources. 

As a result of our spin-off of Harvard Apparatus Regenerative Technology, Inc., now known as Biostage, together with 
certain related transactions, third parties may seek to hold us responsible for Biostage’s liabilities, including liabilities 
that Biostage has assumed from us. 

Third parties may seek to hold us responsible for Biostage’s liabilities, including any of the liabilities that Biostage 
agreed to retain or assume in connection with the separation of the Biostage business from our businesses, and related spin-
off distribution. On April 14, 2017, anticipated representatives for the estate of an individual plaintiff filed a wrongful death 
complaint  with  the  Suffolk  Superior  Court,  in  the  County  of  Suffolk,  Massachusetts,  against  us  and  other  defendants, 
including Biostage, as well as another third party. The complaint seeks payment for an unspecified amount of damages and 
alleges that the plaintiff sustained terminal injuries allegedly caused by products, including synthetic trachea scaffolds and 
bioreactors, provided by certain of the named defendants and utilized in connection with surgeries performed by third parties 

14 

 
 
 
 
 
 
 
 
 
 
 
 
in 2012 and 2013. The litigation is at an early stage and we continue to vigorously defend this case through our liability 
insurance carrier from whom we have requested defense and indemnification of any losses incurred in connection with this 
lawsuit. Any such product liability insurance coverage may not be sufficient to satisfy all liabilities resulting from this claim. 
If claims against us substantially exceed our coverage, then our business could be adversely impacted. While we believe that 
such claim is without merit, we are unable to predict the ultimate outcome of such litigation. Pursuant to our agreements with 
Biostage, Biostage has agreed to indemnify us for claims and losses relating to certain liabilities that it has assumed from us, 
including  liabilities  in  connection  with  the  sale  of  Biostage’s  products,  intellectually  property  infringement  and  other 
liabilities related to the operation of Biostage’s business. However, if those liabilities are significant and we are ultimately 
held liable for them, we cannot assure you that Biostage will have the ability to satisfy its obligations to us, in particular due 
to Biostage having limited revenues, products in early stage development and a need for additional funds in the future. If 
Biostage is unable to satisfy its obligations under its indemnity to us, we may have to satisfy these obligations, which could 
have an adverse impact on our financial condition, results of operations or cash flows. 

If our goodwill or intangible assets become impaired, we may be required to record a significant charge to earnings.  

Under accounting principles generally accepted in the United States, we review our goodwill and intangible assets for 
impairment when events or changes in circumstances indicate the carrying value may not be recoverable. Goodwill is also 
required to be tested for impairment at least annually. Factors that may be considered a change in circumstances indicating 
that the carrying value of our goodwill or other intangible assets may not be recoverable include a decline in our stock price 
and  market  capitalization,  future  cash  flows,  and  slower  growth  rates  in  our  industry.  We  may  be  required  to  record  a 
significant charge to earnings in our financial statements during the period in which any impairment of our goodwill or other 
intangible assets is determined, which could adversely impact our results of operations. 

Accounting for goodwill, other intangible assets and long-lived assets may have an adverse effect on us.  

We assess the recoverability of identifiable intangibles with finite lives and other long-lived assets, such as property, 
plant and equipment, for impairment whenever events or changes in circumstances indicate that the carrying value may not 
be recoverable in accordance with the provisions of Financial Accounting Standards Board (FASB) Accounting Standards 
Codification (ASC) 360, “Property, Plant and Equipment”. In accordance with FASB ASC 350, “Intangibles-Goodwill and 
Other”, goodwill and intangible assets with indefinite lives from acquisitions are evaluated annually, or more frequently, if 
events or circumstances indicate there may be an impairment, to determine whether any portion of the remaining balance of 
goodwill and indefinite lived intangibles may not be recoverable. If it is determined in the future that a portion of our goodwill 
and other intangible assets is impaired, we will be required to write off that portion of the asset according to the methods 
defined by FASB ASC 360 and FASB ASC 350, which could have an adverse effect on net income for the period in which 
the write-off occurs. At December 31, 2017, we had goodwill and intangible assets of $57.2 million, or 52%, of our total 
assets and we concluded that none of our goodwill or other intangible assets was impaired. 

If our accounting estimates are not correct, our financial results could be adversely affected.  

Management judgment and estimates are required in the application of our Critical Accounting Policies. We discuss 
these  estimates  in  the  subsection  entitled  critical  accounting  policies  beginning  on  page  32  in  Item  7,  Management’s 
Discussion  and  Analysis  of  Financial  Condition  and  Results  of  Operations  in  this  Annual  Report.  If  our  estimates  are 
incorrect, our future financial operating results and financial condition could be adversely affected. 

If we fail to retain key personnel and hire, train and retain qualified employees, we may not be able to compete effectively, 
which could result in reduced revenue or increased costs.  

Our success is highly dependent on the continued services of key management, technical and scientific personnel. Our 
management and other employees may voluntarily terminate their employment at any time upon short notice. The loss of the 
services of any member of the senior management team, including the Chief Executive Officer, Jeffrey A. Duchemin; the 
Chief Financial Officer, Robert E. Gagnon; the Vice President, Commercial Operations, Yong Sun; or any of the managerial, 
technical or scientific staff may significantly delay or prevent the achievement of product development, our growth strategies 
and other business objectives. Our future success will also depend on our ability to identify, recruit and retain additional 
qualified scientific, technical and managerial personnel. We operate in several geographic locations where labor markets are 
particularly competitive, including the Boston, Massachusetts metropolitan area, England, and Germany where demand for 
personnel with these skills is extremely high and is likely to remain high. As a result, competition for qualified personnel is 
intense, particularly in the areas of general management, finance, information technology, engineering and science, and the 
process of hiring suitably qualified personnel is often lengthy and expensive, and may become more expensive in the future. 
If we are unable to hire and retain a sufficient number of qualified employees, our ability to conduct and expand our business 
could be seriously reduced. 

15 

 
If we are unable to effectively protect our intellectual property, third parties may use our technology, which would impair 
our ability to compete in our markets.  

Our continued success will depend in significant part on our ability to obtain and maintain meaningful patent protection 
for certain of our products throughout the world. Patent law relating to the scope of claims in the technology fields in which 
we operate is still evolving. The degree of future protection for our proprietary rights is uncertain. We also own numerous 
United States registered trademarks and trade names and have applications for the registration of trademarks and trade names 
pending. We rely on patents to protect a significant part of our intellectual property and to enhance our competitive position. 
However, our presently pending or future patent applications may not be accepted and patents might not be issued, and any 
patent previously issued to us may be challenged, invalidated, held unenforceable or circumvented. Furthermore, the claims 
in patents which have been issued or which may be issued to us in the future may not be sufficiently broad to prevent third 
parties from producing competing products similar to our products. In addition, the laws of various foreign countries in which 
we compete may not protect our intellectual property to the same extent, as do the laws of the United States. If we fail to 
obtain  adequate  patent  protection  for  our  proprietary  technology,  our  ability  to  be  commercially  competitive  could  be 
materially impaired. 

In addition to patent protection, we also rely on protection of trade secrets, know-how and confidential and proprietary 
information.  To  maintain  the  confidentiality  of  trade-secrets  and proprietary  information,  we generally  seek  to  enter  into 
confidentiality agreements with our employees, consultants and strategic partners upon the commencement of a relationship. 
However, we may not be able to obtain these agreements in all circumstances in part due to local regulations. In the event of 
unauthorized use or disclosure of this information, these agreements, even if obtained, may not provide meaningful protection 
for  our  trade-secrets  or  other  confidential  information.  In  addition,  adequate  remedies  may  not  exist  in  the  event  of 
unauthorized use or disclosure of this information. The loss or exposure of our trade secrets and other proprietary information 
would impair our competitive advantages and could have an adverse effect on our operating results, financial condition and 
future growth prospects. 

The manufacture, sale and use of products and services may expose us to product liability claims for which we could have 
substantial liability.  

We face an inherent business risk of exposure to product liability claims if our products, services or product candidates, 
including without limitation, any of our life science research tools are alleged or found to have caused injury, damage or loss. 
We may in the future be unable to obtain insurance with adequate levels of coverage for potential liability on acceptable 
terms or claims of this nature may be excluded from coverage under the terms of any insurance policy that we can obtain. If 
we are unable to obtain such insurance or the amounts of any claims successfully brought against us substantially exceed our 
coverage, then our business could be adversely impacted. 

We may be involved in lawsuits to protect or enforce our patents that would be expensive and time-consuming.  

In order to protect or enforce our patent rights, we may  initiate patent litigation against third parties. We may also 
become subject to interference proceedings conducted in the patent and trademark offices of various countries to determine 
the  priority  of  inventions.  Several  of  our  products  are  based  on  patents  that  are  closely  surrounded  by  patents  held  by 
competitors or potential competitors. As a result, we believe there is a greater likelihood of a patent dispute than would be 
expected if our patents were not closely surrounded by other patents. The defense and prosecution, if necessary, of intellectual 
property  suits,  interference  proceedings  and  related  legal  and  administrative  proceedings  would  be  costly  and  divert  our 
technical and management personnel from their normal responsibilities. We may not prevail in any of these suits should they 
occur. An adverse determination of any litigation or defense proceedings could put our patents at risk of being invalidated or 
interpreted narrowly and could put our patent applications at risk of being rejected and no patents being issued. 

Furthermore, because of the substantial amount of discovery required in connection with intellectual property litigation, 
there is a risk that some of our confidential information could be compromised by disclosure during this type of litigation. 
For example, during the course of this kind of litigation, there could be public announcements of the results of hearings, 
motions or other interim proceedings or developments in the litigation. Securities analysts or investors may perceive these 
announcements to be negative, which could cause the market price of our stock to decline. 

Our success will depend partly on our ability to operate without infringing on or misappropriating the intellectual property 
rights of others.  

We may be sued for infringing on the intellectual property rights of others, including the patent rights, trademarks and 
trade names of third parties. Intellectual property litigation is costly and the outcome is uncertain. If we do not prevail in any 
intellectual property litigation, in addition to any damages we might have to pay, we could be required to stop the infringing 
activity, or obtain a license to or design around the intellectual property in question. If we are unable to obtain a required 

16 

license on acceptable terms, or are unable to design around any third party patent, we may be unable to sell some of our 
products and services, which could result in reduced revenue. 

Rising commodity and precious metals costs could adversely impact our profitability.  

Raw material commodities such as resins, and precious metal commodities such as platinum are subject to wide price 
variations. Increases in the costs of these commodities and the costs of energy, transportation and other necessary services 
may adversely affect our profit margins if we are unable to pass along any higher costs in the form of price increases or 
otherwise achieve cost efficiencies such as in manufacturing and distribution. 

Regulations related to conflict minerals may force us to incur additional expenses and otherwise adversely impact our 
business. 

The SEC has promulgated final rules mandated by the Dodd-Frank Act regarding disclosure of the use of tin, tantalum, 
tungsten  and  gold,  known  as  conflict  minerals,  in  products  manufactured  by  public  companies.  These  new  rules  require 
ongoing due diligence to determine whether such minerals originated from the Democratic Republic of Congo (the DRC) or 
an adjoining country and whether such minerals helped finance the armed conflict in the DRC. Reporting obligations for the 
rule began on May 31, 2014 and are required annually thereafter. There will be costs associated with complying with these 
disclosure requirements, including costs to determine the origin of conflict minerals in our products. The implementation of 
these rules and their effect on customer, supplier and/or consumer behavior could adversely affect the sourcing, supply and 
pricing of materials used in our products. As a result, we may also incur costs with respect to potential changes to products, 
processes or sources of supply. We may face disqualification as a supplier for customers and reputational challenges if the 
due diligence procedures we implement do not enable us to verify the origins for all conflict minerals used in our products, 
including that such minerals did not originate from any of the covered conflict countries. Accordingly, the implementation 
of these rules could have an adverse effect on our business, results of operations and/or financial condition. 

Provisions of Delaware law, of our charter and bylaws may make a takeover more difficult, which could cause our stock 
price to decline.  

Provisions in our certificate of incorporation and bylaws and in the Delaware corporate law may make it difficult and 
expensive for a third party to pursue a tender offer, change in control or takeover attempt, which is opposed by management 
and  the  board  of  directors.  Public  stockholders  who  might  desire  to  participate  in  such  a  transaction  may  not  have  an 
opportunity to do so. We have a staggered board of directors that makes it difficult for stockholders to change the composition 
of the board of directors in any one year. These anti-takeover provisions could  substantially impede the ability of public 
stockholders to change our management and board of directors. Such provisions may also limit the price that investors might 
be willing to pay for shares of our common stock in the future. 

An active trading market for our common stock may not be sustained.  

Although our common stock is quoted on the NASDAQ Global Market, an active trading market for the shares may 
not be sustained. This could negatively affect the price for our common stock, including investors’ ability to buy or sell our 
common stock and the listing thereof. 

Your percentage ownership will be diluted in the future because of equity award issuances. 

Your percentage ownership will be diluted in the future because of equity awards that we expect will be granted to our 
directors, officers and employees, as well as shares of common stock, or securities convertible into common stock, we issue 
in connection with future capital raising or strategic transactions. Our Third Amended and Restated 2000 Stock Option and 
Incentive Plan provides for the grant of equity-based awards, including restricted stock, restricted stock units, stock options, 
stock  appreciation  rights  and  other  equity-based  awards  to  our  directors,  officers  and  other  employees,  advisors  and 
consultants. The issuance of any shares of our stock would dilute the proportionate ownership and voting power of existing 
security holders. 

Any issuance of preferred stock in the future may dilute the rights of our common stockholders.  

Our board of directors has the authority to issue up to 5,000,000 shares of preferred stock and to determine the price, 
privileges and other terms of these shares. The board of directors may exercise this authority without any further approval of 
stockholders. The rights of the holders of common stock may be adversely affected by the rights of future holders of preferred 
stock. 

17 

 
 
Cash dividends will not likely be paid on our common stock.  

Currently, we intend to retain all of our earnings to finance the expansion and development of our business and do not 
anticipate paying any cash dividends to holders of our common stock in the near future. As a result, capital appreciation, if 
any, of our common stock will be a stockholder’s sole source of gain for the near future. 

Changes in the European regulatory environment regarding privacy and data protection regulations could have a material 
adverse impact on our results of operations. 

The E.U. has recently adopted a comprehensive overhaul of its data protection regime in the form of the General Data 
Protection Regulation (GDPR), which comes into effect in May 2018. GDPR extends the scope of the existing E.U. data 
protection law to foreign companies processing personal data of E.U. residents. The regulation imposes a strict data protection 
compliance regime with severe penalties of 4% of worldwide turnover or €20 million, whichever is greater, and includes new 
rights such as the right of erasure of personal data. Although the GDPR will apply across the E.U., as has been the case under 
the current data protection regime, E.U. Member States have some national derogations and local data protection authorities 
(DPAs) will still have the ability to interpret the GDPR, which has the potential to create inconsistencies on a country-by-
country basis. Implementation of, and compliance with the GDPR could increase our cost of doing business and/or force us 
to  change our business  practices  in  a  manner  adverse  to our business. In  addition,  violations of  the GDPR  may  result  in 
significant fines, penalties and damage to our brand and business which could, individually or in the aggregate, materially 
harm our business and reputation. 

Item  1B.  Unresolved Staff Comments.  

None. 

Item  2. 

Properties.  

Our principal facilities incorporate manufacturing, research and development, sales and marketing, and administration 

functions. Our facilities consist of: 

• a leased 83,123 square foot facility in Holliston, Massachusetts, which includes our corporate headquarters, 
• a leased 29,020 square foot facility in Richmond, California, 
• a leased 22,449 square foot facility in Reutlingen, Germany, 
• a leased 20,853 square foot facility in Barcelona, Spain, 
• a leased 12,031 square foot facility in March-Hugstetten, Germany, 

Excluded  from  the  listing  of  facilities  above,  is  the  115,667  square  foot  facility  leased  by  DSI  in  New  Brighton, 

Minnesota, and the 36,144 square foot facility in Charlotte, North Carolina that was leased by Denville. 

We also lease additional facilities in Cambourne, England, Lambrecht, Germany, Hamden Connecticut, Durham, North 
Carolina and Kista, Sweden, Shanghai, China, Les Ulis, France, St. Augustin, Germany, Lunenburg, Canada and Montreal, 
Canada. 

We believe our current facilities are adequate for our needs for the foreseeable future. 

Item  3. 

Legal Proceedings.  

On April 14, 2017, anticipated representatives for the estate of an individual plaintiff filed a wrongful death complaint 
with  the  Suffolk  Superior  Court,  in  the  County  of  Suffolk,  Massachusetts,  against  the  Company  and  other  defendants, 
including Biostage, Inc. (f/k/a Harvard Apparatus Regenerative Technology, Inc.), our former subsidiary that was spun off 
in 2013, as well as another third party. The complaint seeks payment for an unspecified amount of damages and alleges that 
the plaintiff sustained terminal injuries allegedly caused by products, including synthetic trachea scaffolds and bioreactors, 
provided by certain of the named defendants and utilized in connection with surgeries performed by third parties in 2012 and 
2013. The litigation is at an early stage and the Company intends to vigorously defend this case and has contacted its liability 
insurance carrier to request defense and indemnification of any losses incurred in connection with this lawsuit. While we 
believe that such claim is without merit, we are unable to predict the ultimate outcome of such litigation. 

Item 4. 

Mine Safety Disclosures 

Not Applicable. 

18 

 
 
  
 
 
 
 
PART II 

Item  5. 

Market  for  Registrant’s  Common  Equity,  Related  Stockholder  Matters  and  Issuer  Purchases  of  Equity
Securities.  

Price Range of Common Stock  

Our common stock has been quoted on the NASDAQ Global Market since our initial public offering on December 7, 
2000, and currently trades under the symbol “HBIO.” The following table sets forth the range of the high and low sales prices 
per share of our common stock as reported on the NASDAQ Global Market for the quarterly periods indicated. 

Fiscal Year Ended December 31, 2017 
First Quarter ....................................................................................................................   $ 
Second Quarter ................................................................................................................   $ 
Third Quarter ...................................................................................................................   $ 
Fourth Quarter .................................................................................................................   $ 

High 

Low 

3.25    $
2.75    $
3.75    $
3.80    $

Fiscal Year Ended December 31, 2016 
First Quarter ....................................................................................................................   $ 
Second Quarter ................................................................................................................   $ 
Third Quarter ...................................................................................................................   $ 
Fourth Quarter .................................................................................................................   $ 

High 

Low 

3.25    $
3.83    $
3.19    $
3.05    $

2.55   
2.30   
2.35   
3.08   

2.48   
2.72   
2.53   
2.30   

On March 9, 2018, the closing sale price of our common stock on the NASDAQ Global Market was $4.60 per share. 
There were 116 holders of record of our common stock as of March 9, 2018. We believe that the number of beneficial owners 
of our common stock at that date was substantially greater. 

Dividend Policy  

We have never declared or paid cash dividends on our common stock in the past and do not intend to pay cash dividends 
on our common stock in the foreseeable future. Any future determination to pay cash dividends will be at the discretion of 
our Board of Directors and will depend on our financial condition, results of operations, capital requirements and other factors 
our Board of Directors deems relevant. 

Stockholder Return Performance Graph  

This performance graph shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, 
as amended (the Exchange Act), or incorporated by reference into any filing of Harvard Bioscience under the Securities Act 
of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such filing. 

The following graph provides a comparison of the cumulative total stockholder return on the Company’s common stock 
from  December 31,  2012  to  December 31,  2017  with  the  cumulative  return  of  the  Russell  2000  Index  and  the  Nasdaq 
Biotechnology Index over the same period. The five-year cumulative return assumes an initial investment of $100 in the 
Company’s common stock and in each index on December 31, 2012. The total return for the Company’s common stock and 
the indices used assumes the reinvestment of all dividends. The table below reflects the stock prices as adjusted for the spin-
off of HART which was effected on November 1, 2013, for all periods presented. 

19 

  
 
  
  
  
  
  
  
  
  
  
  
  
  
  
  
12/12    

12/13  

  12/14    

  12/15     

  12/16    

   12/17  

Harvard Bioscience, Inc. ....................................   
Russell 2000 .........................................................   
NASDAQ Biotechnology ....................................   

   100.00        141.63        170.86        104.56        91.91        99.44  
   100.00        138.82        145.62        139.19        168.85        193.58  
   100.00        174.05        230.33        244.29        194.95        228.29  

The stock price performance included in this graph is not necessarily indicative of future stock price performance. 

Item 6. 

Selected Financial Data 

The financial data presented below have been derived from our audited consolidated financial statements. The selected 
historical financial data presented below should be read in conjunction with “Item 7. Management’s Discussion and Analysis 
of Financial Condition and Results of Operations” and “Item 8. Financial Statements and Supplementary Data.” and with our 
previously filed Annual Reports on Form 10-K. The selected data in this section is not intended to replace the consolidated 
financial statements. The information presented below is not necessarily indicative of the results of our future operations. 

20 

 
 
  
  
  
  
  
     
     
     
     
     
  
   
  
 
 
2017 

For The Year Ended December 31, 
2014 
2015 
2016 
(in thousands, except per share data) 

2013 

Statement of Operations Data: 
Revenues ..................................................................................    $  101,882     $  104,521    $  108,664    $  108,663    $  105,171  
57,475  
Cost of revenues .......................................................................      
47,696  
Gross profit ..........................................................................      
46,159  
Operating expenses ..................................................................      
1,537  
Operating (loss) income .......................................................      
Other expense, net ...............................................................      
(1,102) 
(Loss) income from continuing operations before income 

54,285       
47,597       
47,698       
(101 )     
(1,987 )     

59,941      
48,723      
50,436      
(1,713)     
(1,895)     

59,319      
49,344      
42,726      
6,618      
(2,201)     

56,106      
48,415      
51,412      
(2,997)     
(81)     

taxes (1) ............................................................................     
Income tax expense (benefit) (2) ..............................................      
(Loss) income from continuing operations ..........................      

(2,088 )     
(1,223 )     
(865 )     

(3,078)     
1,229      
(4,307)     

(3,608)     
15,431      
(19,039)     

4,417      
2,062      
2,355      

435  
(288) 
723  

Discontinued operations (3): 

Loss from discontinued operations, net of tax .....................      
Net (loss) income .................................................................    $ 

-       
(865 )   $ 

-      
(4,307)   $ 

-      
(19,039)   $ 

-      
2,355    $ 

(2,553) 
(1,830) 

(Loss) earnings per share: 

Basic (loss) earnings per common share from continuing 

operations .........................................................................   $ 
Discontinued operations ......................................................      
Basic (loss) earnings per common share ..............................    $ 

(0.02 )   $ 
-       
(0.02 )   $ 

(0.13)   $ 
-      
(0.13)   $ 

(0.57)   $ 
-      
(0.57)   $ 

0.07    $ 
-      
0.07    $ 

Diluted (loss) earnings per common share from continuing 

operations .........................................................................   $ 
Discontinued operations ......................................................      
Diluted (loss) earnings per common share ...........................    $ 

(0.02 )   $ 
-       
(0.02 )   $ 

(0.13)   $ 
-      
(0.13)   $ 

(0.57)   $ 
-      
(0.57)   $ 

0.07    $ 
-      
0.07    $ 

0.02  
(0.08) 
(0.06) 

0.02  
(0.08) 
(0.06) 

Weighted average common shares: 

Basic ....................................................................................      
Diluted .................................................................................      

34,753       
34,753       

34,212      
34,212      

33,593      
33,593      

32,171      
33,237      

30,384  
31,914  

2017 

2016 

As of December 31, 
2015 
(in thousands) 

2014 

2013 

Balance Sheet Data: 
Cash and cash equivalents ........................................................    $ 
Working capital ........................................................................      
Total assets ...............................................................................      
Long-term debt, net of current portion .....................................      
Stockholders’ equity ................................................................      

5,733     $ 
33,494       
109,354       
8,983       
80,900       

5,596    $ 
30,871      
107,765      
11,374      
72,196      

6,744    $ 
31,226      
120,050      
16,369      
77,598      

14,134    $ 
38,964      
135,916      
16,450      
95,468      

25,771  
44,665  
135,460  
19,750  
94,485  

(1) 

Included in the net operating loss for the year ended December 31, 2016 was $1.7 million of forensic investigation costs from
the first half, a $0.7 million AHN impairment charge from the third quarter, and a $1.2 million loss on sale of AHN from the
fourth quarter. The total impact of these three charges, on a pre-tax basis, was $3.6 million for the year ended December 31,
2016. 

(2) 

Income tax expense for the year ended December 31, 2015 is primarily the result of the recognition of a valuation allowance
on U.S. deferred tax assets. 

(3)  On September 30, 2008, we completed the sale of assets of our Union Biometrica Division including its German subsidiary, 
Union Biometrica GmbH, representing at that time the remaining portion of our Capital Equipment Business Segment, to UBIO
Acquisition Company. The purchase price paid by UBIO Acquisition Company included an earn-out based on the revenue 
generated by the acquired business over a five-year post-transaction period. Discontinued operations include a gain on disposal
related to the earn-out, net of tax, of $0.3 million in 2013. 

On November 1, 2013, the spin-off of our RMD business from our Company was completed. Through the spin-off date the 
historical operations of RMD were reported as continuing operations in our consolidated statements of operations. Following
the spin-off, and reported herein, the historical operations of RMD were restated and presented as discontinued operations in
our consolidated statements of operations presented. Discontinued operations include the results of the RMD business except
for certain corporate overhead costs and other allocations, which remain in continuing operations.  The costs incurred to separate 
and spin-off  the RMD business remain in continuing operations and have been classified and reported as transaction costs,
within  operating  expenses,  on  our  consolidated  statements  of  operations.  Discontinued  operations  include  losses  from
operations of the RMD business, net of tax, for 2013 of $2.8 million. 

21 

  
  
  
  
  
    
    
    
    
  
  
  
  
    
        
       
       
       
   
    
        
       
       
       
   
    
        
       
       
       
   
  
    
        
       
       
       
   
  
    
        
       
       
       
   
    
        
       
       
       
   
  
  
  
  
  
  
    
    
    
    
  
  
  
  
    
        
       
       
       
   
   
 
 
 
 
 
 
 
 
  
  
  
  
  
Item 7. 

Management’s Discussion and Analysis of Financial Condition and Results of Operations. 

Forward-Looking Statements  

The  following  section  of  this  Annual  Report  on  Form 10-K  entitled  “Management’s  Discussion  and  Analysis  of 
Financial  Condition  and  Results  of  Operations”  contains  statements  that  are  not  statements  of  historical  fact  and  are 
forward-looking  statements  within  the  meaning  of  federal  securities  laws.  These  statements  involve  known  and  unknown 
risks,  uncertainties  and  other  factors  that  may  cause  our  actual  results,  performance  or  achievements  to  be  materially 
different from any future results, performance or achievements expressed or implied by the forward-looking statements. These 
statements reflect our current views with respect to future events and are based on assumptions and subject to risks and 
uncertainties. Factors that may cause our actual results to differ materially from those in the forward-looking statements 
include those factors described in “Item 1A. Risk Factors” beginning on page 7 of this Annual Report on Form 10-K. You 
should carefully review all of these factors, as well as the comprehensive discussion of forward-looking statements on page 1 
of this Annual Report on Form 10-K. 

Overview  

Harvard Bioscience, Inc., a Delaware corporation, is a global developer, manufacturer and marketer of a broad range 
of scientific instruments, systems and lab consumables used to advance life science for basic research, drug discovery, clinical 
and environmental testing. Our products are sold to thousands of researchers in over 100 countries through our global sales 
organization, websites, catalogs, and through distributors including Thermo Fisher Scientific Inc., VWR and other specialized 
distributors.  We  have  sales  and  manufacturing  operations  in  the  United  States,  the  United  Kingdom,  Germany,  Sweden, 
Spain, France, Canada, and China. 

Led by President and CEO Jeffrey A. Duchemin, we have conducted a multi-year restructuring program to reduce costs, 
align global functions, consolidate facilities to optimize our global footprint, divest non-core businesses and to reinvest in 
key  areas  such  as  sales  and  common  IT  systems.  As  part  of  these  efforts,  we  divested  our  AHN  Biotechnologie  GmbH 
subsidiary (AHN) in the fourth quarter of 2016 and, during the first quarter of 2018, we sold substantially all the assets of our 
wholly-owned subsidiary, Denville Scientific, Inc. (Denville). 

We  are  also  pursuing  a  strategy  to  grow  the  business  through  strategic,  accretive  acquisitions,  including  four 

acquisitions since the fourth quarter of 2014. 

Most recently, in January 2018, we acquired Data Sciences International, Inc. (DSI) for approximately $70.0 million. 
DSI, a St. Paul, Minnesota-based life science research company, is a recognized leader in physiologic monitoring focused on 
delivering preclinical products, systems, services and solutions to its customers. Its customers include pharmaceutical and 
biotechnology  companies,  as  well  as  contract  research  organizations,  academic  labs  and  government  researchers.  This 
acquisition diversifies our customer base into the biopharmaceutical and contract research organization markets and offers 
revenue and cost synergies. 

22 

 
  
  
  
  
  
  
  
 
 
 
Our Strategy  

Our vision is to be a world leading life science company that excels in meeting the needs of our customers by providing 
a wide breath of innovative products and solutions, while providing exemplary customer service. Our business strategy is to 
grow our top-line and bottom-line, and build shareholder value through a commitment to: 

• 

• 

• 

• 

commercial excellence; 

new product development; 

strategic acquisitions; and 

operational efficiencies. 

In the table below, we provide an overview of selected operating metrics. 

     % of 
    Revenues      

     % of 
    Revenues      

2016 

     % of 
     Revenues   

2015 

2017 

(dollars in thousands) 

Revenues ..................................................   $  101,882      
54,285      
Cost of revenues .......................................     
21,036      
Sales and marketing expenses ..................     
18,575      
General and administrative expenses .......     
5,645      
Research and development expenses ........     
Restructuring (credits) charges .................     
-      
2,442      
Amortization of intangible assets .............     
-      
Impairment charges ..................................     
-      
Loss on sale of AHN ................................     

      $ 104,521      
56,106      
20,486      
20,950      
5,392      
(4)     
2,722      
676      
1,190      

53.3%    
20.6%    
18.2%    
5.5%    
0.0%    
2.4%    
0.0%    
0.0%    

      $ 108,664      
59,941      
20,577      
19,832      
6,420      
788      
2,819      
-      
-      

53.7%     
19.6%     
20.0%     
5.2%     
0.0%     
2.6%     
0.6%     
1.1%     

55.2 %
18.9 %
18.3 %
5.9 %
0.7 %
2.6 %
0.0 %
0.0 %

Components of Operating Income 

Revenues.     We  generate  revenues  by  selling  apparatus,  instruments,  devices  and  consumables  through  our 
distributors,  direct  sales  force,  websites  and  catalogs.  Our  websites  and  catalogs  serve  as  the  primary  sales  tools  for  our 
various product lines. These product lines include both proprietary manufactured products and complementary products from 
various suppliers. Our reputation as a leading producer in many of our manufactured products creates traffic to our website, 
enables cross-selling and facilitates the introduction of new products. We have field sales teams in the U.S., Canada, the 
United Kingdom, Germany, France, Spain and China. In those regions where we do not have a direct sales team, we use 
distributors. Revenues from direct sales to end users represented approximately 65%, 64% and 63% of our revenues for the 
years ended December 31, 2017, 2016 and 2015, respectively. 

Our products consist of instruments, consumables, and systems that are made up of several individual products. Sales 
prices of these products are mostly priced in the range of $5,000 to $15,000, but range from under $100 to over $100,000. 
They are mainly scientific instruments like spectrophotometers and plate readers that analyze light to detect and quantify a 
wide range of molecular and cellular processes, or apparatus like gel electrophoresis units. We also use distributors for both 
our catalog products and our higher priced products, for sales in locations where we do not have subsidiaries or where we 
have  existing  distributors  in  place  from  acquired  businesses.  For  the  years  ended  December  31,  2017,  2016  and  2015, 
approximately 35%, 36% and 37% of our revenues, respectively, were derived from sales to distributors. 

For the years ended December 31, 2017, 2016 and 2015, approximately 62% of our revenues, for all periods, were 
derived from products we manufacture, approximately 14%, 14% and 13%, respectively, were derived from complementary 
products we distribute in order to provide the researcher with a single source for all equipment needed to conduct a particular 
experiment. Approximately 24%, 24% and 25% of our revenues, respectively, for the years ended December 31, 2017, 2016, 
2015 were derived from distributed products sold under our brand names. 

For  the  years  ended  December  31,  2017,  2016  and  2015,  approximately  35%,  38%  and  40%  of  our  revenues, 
respectively, were derived from sales made by our non-United States operations. The decrease in international revenues was 
primarily due to the impact of the loss of revenue following the AHN disposition, the effects of currency fluctuation, and the 
impact of softness in the European funding environment. 

23 

  
   
  
 
  
 
  
 
  
  
  
    
       
       
  
  
  
  
  
  
    
  
  
  
  
  
Changes in the relative proportion of our revenue sources between catalog or website sales, direct sales and distribution 

sales are primarily the result of a different sales proportion of acquired companies and changes in geographic mix. 

Cost  of  revenues.     Cost  of  revenues  includes  material,  labor  and  manufacturing  overhead  costs,  obsolescence 
charges, packaging costs, warranty costs, shipping costs and royalties. Our cost of revenues may vary over time based on the 
mix of products sold. We sell products that we manufacture and products that we purchase from third parties. The products 
that we purchase from third parties typically have a higher cost of revenues as a percent of revenues because the profit is 
effectively shared with the original manufacturer. We anticipate that our manufactured products will continue to have a lower 
cost of revenues as a percentage of revenues as compared with the cost of non-manufactured products for the foreseeable 
future. Additionally, our cost of revenues as a percent of revenues will vary based on mix of direct to end user sales and 
distributor sales, mix by product line and mix by geography. 

Sales and marketing expenses.     Sales and marketing expense consists primarily of salaries and related expenses for 
personnel in sales, marketing and customer support functions. We also incur costs for travel, trade shows, demonstration 
equipment, public relations and marketing materials, consisting primarily of the printing and distribution of our catalogs, 
supplements and the maintenance of our websites. We may from time to time expand our marketing efforts by employing 
additional technical marketing specialists in an effort to increase sales of selected categories of products. We may also from 
time to time expand our direct sales organizations in an effort to concentrate on key accounts or promote certain product 
lines. 

General and administrative expenses.     General and administrative expense consists primarily of salaries and other 
related costs for personnel in executive, finance, accounting, information technology and human resource functions. Other 
costs include professional fees for legal and accounting services, facility costs, investor relations, insurance and provision for 
doubtful accounts. 

Research and development expenses.     Research and development expense consists primarily of salaries and related 
expenses for personnel and spending to develop and enhance our products. Other research and development expense includes 
fees for consultants and outside service providers, and material costs for prototype and test units. We expense research and 
development  costs  as  incurred.  From  time  to  time,  we  receive  grants  from  governmental  entities  in  relation  to  research 
projects. Such grants received are accounted for as a reduction in research and development expense over the period of the 
project. We believe that investment in product development is a competitive necessity and plan to continue to make these 
investments in order to realize the potential of new technologies that we develop, license or acquire for existing markets. 

Restructuring charges.     Restructuring charges consist of severance, other personnel-related charges and exit costs 

related to plans to create organizational efficiencies and reduce operating expenses. 

Amortization of intangibles.   Amortization of intangibles expense consists of the expensing of the costs of the finite 

lived intangible assets over the useful life of the assets.  

Stock-based compensation expenses.     Stock-based compensation expense for the years ended December 31, 2017, 
2016 and 2015 was $3.5 million, $3.5 million and $2.8 million, respectively. The stock-based compensation expense related 
to stock options, restricted stock units, restricted stock units with a market condition and the employee stock purchase plan 
and was recorded as a component of cost of revenues, sales and marketing expenses, general and administrative expenses, 
research and development expenses and discontinued operations. 

Currently, we intend to retain all of our earnings to pay down debt, finance the expansion and development of our 
business and do not anticipate paying any cash dividends to holders of our common stock in the near future. As a result, 
capital appreciation, if any, of our common stock will be a stockholder’s sole source of gain for the near future. 

24 

  
  
  
  
  
  
  
  
 
 
Selected Results of Operations 

Year Ended December 31, 2017 compared to Year Ended December 31, 2016 

Revenues  

Revenues decreased 2.6%, or $2.6 million, to $101.9 million for the year ended December 31, 2017, compared to 

revenues of $104.5 million for the year ended December 31, 2016.   

The loss in revenues from the October 2016 AHN disposition negatively impacted 2017 revenues by approximately 
$2.1 million, while the impact of currency translation negatively impacted 2017 revenues by approximately $0.3 million. 
Excluding the impact of the AHN disposition and currency translation, organic revenues declined approximately $0.3 million, 
or 0.2%. 

Reconciliation of Changes In Revenues Compared to the Same Period of the Prior Year 

 For the Year Ended   
  December 31, 2017   

Organic and AHN change ....................................................................................................................     

Foreign exchange effect .......................................................................................................................     

Total revenue change............................................................................................................................     

-2.3%

-0.3%

-2.6%

Each reporting period, we face currency exposure that arises from translating the results of our worldwide operations 
to the United States dollar at exchange rates that fluctuate from the beginning of such period. We evaluate our results of 
operations  on  both  a  reported  and  a  foreign  currency-neutral  basis,  which  excludes  the  impact  of  fluctuations  in  foreign 
currency  exchange  rates.  We  believe  that  disclosing  this  non-GAAP  financial  information  provides  investors  with  an 
enhanced understanding of the underlying operations of the business. This non-GAAP financial information is used by our 
management to internally evaluate our operating results. The non-GAAP financial information provided in the table above 
should be considered in addition to, not as a substitute for, the financial information provided and presented in accordance 
with accounting principles generally accepted in the United States, or GAAP and may be different than other companies’ 
non-GAAP financial information. 

Cost of revenues 

Cost  of  revenues  were  $54.3  million  for  the  year  ended  December  31,  2017,  a  decrease  of  $1.8  million,  or  3.2%, 
compared with $56.1 million for the year ended December 31, 2016. The decrease in cost of revenues was primarily due to 
the decrease in sales, including the effect of cost of revenues from the sale of AHN of approximately $1.6 million. Gross 
profit margin as a percentage of revenues increased slightly to 46.7% for the year ended December 31, 2017 compared with 
46.3% for 2016. 

Sales and marketing expenses 

Sales and marketing expenses increased $0.5 million, or 2.7%, to $21.0 million for the year ended December 31, 2017 
compared with $20.5 million for the year ended December 31, 2016. This increase was due to increases in employee costs 
and stock compensation offset by decreases in consulting and purchased services as well as the impact of the sale of AHN. 

General and administrative expenses 

General and administrative expenses were $18.6 million for the year ended December 31, 2017, a decrease of $2.4 
million, or 11.3%, compared with $21.0 million for the year ended December 31, 2016. The decrease was primarily due to a 
decrease in audit costs, consulting and purchased services costs, as well as the impact of the sale of AHN. 

Research and development expenses  

Research and development expenses were $5.6 million for the year ended December 31,  2017, an increase of $0.2 
million, or 4.7%, compared with $5.4 million for the year ended December 31, 2016. The increase was primarily due to an 

25 

  
  
  
  
  
  
  
  
  
   
   
  
   
   
  
   
   
  
  
  
  
  
  
  
  
  
increase in employee, consulting and other purchased services due to investments in product development and compliance 
efforts. 

Amortization of intangible assets 

Amortization of intangible asset expenses was $2.4 million for the year ended December 31, 2017 compared with $2.7 
million for the year ended December 31, 2016. The decrease in amortization expense was due to some long-lived intangibles 
having become fully amortized in 2016, as well as the impact of the disposal of AHN. 

Impairment charges 

During the third quarter of 2016, we initiated plans to sell the operations of AHN. As a result of initiating the plan to 
sell  the  operations  of  AHN,  we  evaluated  the  long-lived  assets  for  impairment,  pursuant  to  ASC  360-10.  Based  on  the 
resulting impairment analysis, we recognized an impairment charge of $0.7 million for the year ended December 31, 2016. 

Loss on sale of AHN 

The loss on sale of AHN was $1.2 million for the year ended December 31, 2016. During the fourth quarter of 2016, 
we concluded the sale of AHN. Upon the closing of the transaction, we recorded a loss on sale of $1.2 million for the year 
ended December 31, 2016. 

Other expense, net 

Other expense, net, was $2.0 million and $0.1 million for the years ended December 31, 2017 and 2016, respectively. 
Included in other expense, net for the year ended December 31, 2017 was $0.7 million of interest expense and $0.7 million 
of transaction related costs, including due diligence and deal investigative activities. For the year ended December 31, 2016, 
other expense, net included $0.6 million of interest expense. The increase in other expense, net was primarily due to the 
increase in transaction related costs and currency exchange rate fluctuations. Currency exchange rate fluctuations included 
as a component of net loss resulted in approximately $0.5 million in currency losses during the year ended December 31, 
2017, compared to $0.7 million in currency gains during the year ended December 31, 2016. 

Income taxes 

Income tax was a benefit of approximately $1.2 million and an expense of $1.2 million for the years ended December 
31, 2017 and 2016, respectively. The decrease in income tax expense year over year was primarily attributable to a reduction 
in the valuation allowance recorded against US net deferred tax assets in 2017, partially offset by tax expense associated with 
the remeasurement of net federal deferred tax assets. These events result directly from recent U.S. tax reform legislation 
which is discussed below. 

On December 22, 2017, tax reform legislation known as the Tax Cuts and Jobs Act (the Tax Act) was signed into law. 
The Tax Act makes broad and complex changes to the U.S. Internal Revenue Code, including the reduction of the corporate 
income tax rate from 35% to 21% and the implementation of a modified territorial tax system; the latter includes a one-time 
transition tax on previously unremitted earnings of foreign subsidiaries. The Company has recorded provisional estimates 
related  to  repatriation  tax  impact  and  changes  in  the  revaluation  of  net  deferred  tax  assets  in  the  consolidated  financial 
statements. Other provisions of the Tax Act will not impact the Company until the tax year ended December 31, 2018. 

Year Ended December 31, 2016 compared to Year Ended December 31, 2015 

Revenues  

Revenues  decreased  3.8%,  or  $4.2  million,  to  $104.5  million  for  the  year  ended  December  31,  2016,  compared  to 

revenues of $108.7 million for the year ended December 31, 2015.   

Excluding the effects of currency translation, primarily from the weakening of the British Pound against the U.S. dollar, 
our revenues decreased 1.8% or $2.0 million, from the previous year. The remainder of the decline in revenues was primarily 
the result of softness in the European funding environment and slower than expected NIH budget funding, as well as less 
revenues from AHN in 2016 compared to 2015, following its sale in October 2016, due to two fewer months of revenue 
which amounted to approximately $0.5 million. 

26 

  
  
 
  
  
  
  
  
  
  
  
  
  
  
  
 
 
Reconciliation of Changes In Revenues Compared to the Same Period of the Prior Year 

 For the Year Ended   
  December 31, 2016   

Organic and AHN change ....................................................................................................................     

Foreign exchange effect .......................................................................................................................     

Total revenue change............................................................................................................................     

-1.8%

-2.0%

-3.8%

Each reporting period, we face currency exposure that arises from translating the results of our worldwide operations 
to the United States dollar at exchange rates that fluctuate from the beginning of such period. We evaluate our results of 
operations  on  both  a  reported  and  a  foreign  currency-neutral  basis,  which  excludes  the  impact  of  fluctuations  in  foreign 
currency  exchange  rates.  We  believe  that  disclosing  this  non-GAAP  financial  information  provides  investors  with  an 
enhanced understanding of the underlying operations of the business. This non-GAAP financial information approximates 
information  used  by  our  management  to  internally  evaluate  our  operating  results.  The  non-GAAP  financial  information 
provided in the table above should be considered in addition to, not as a substitute for, the financial information provided and 
presented in accordance with accounting principles generally accepted in the United States, or GAAP. 

Cost of revenues 

Cost  of  revenues  were  $56.1  million  for  the  year  ended  December  31,  2016,  a  decrease  of  $3.8  million,  or  6.4%, 
compared  with  $59.9  million  for  the  year  ended  December  31,  2015.  Gross  profit  margin  as  a  percentage  of  revenues 
increased to 46.3% for the year ended December 31, 2016 compared with 44.8% for 2015. The increase in gross profit margin 
was due primarily due to the savings associated with the relocation and consolidation of certain facilities in 2015. 

Sales and marketing expenses 

Sales and marketing expenses decreased $0.1 million, or 0.4%, to $20.5 million for the year ended December 31, 2016 
compared with $20.6 million for the year ended December 31, 2015. The decrease was primarily due to favorable currency 
translation and the impact of our restructuring activities. 

General and administrative expenses 

General and administrative expenses were $21.0 million for the year ended December 31, 2016, an increase of $1.2 
million, or 5.6%, compared with $19.8 million for the year ended December 31, 2015. The increase was primarily due to 
audit and forensic investigation costs, higher stock compensation expense, partially offset by favorable currency translation, 
and the impact of our restructuring activities. 

Research and development expenses 

Research  and  development  expenses  were  $5.4  million  for  the  year  ended  December  31,  2016,  a  decrease  of  $1.0 
million, or 16.0%, compared with $6.4 million for the year ended December 31, 2015. The decrease was primarily due to the 
impact of our restructuring activities, favorable currency translation, and an increase in the amount of research grants earned. 
Research grants earned are accounted for as a reduction in research and development expense. 

Restructuring 

Restructuring charges were immaterial for the year ended December 31, 2016 compared with $0.8 million for the year 

ended December 31, 2015. There were no restructuring activities during the year ended December 31, 2016. 

Restructuring charges recorded during the year ended December 31, 2015 included additional charges related to the 
restructuring plan we implemented during the year ended December 31, 2014, as well as charges related to restructuring plans 
commenced during the year ended December 31, 2015. The 2015 restructuring plans included actions to move the Coulbourn 
Instruments’ operations to Holliston, MA and the HEKA Canada operations to HEKA Germany, as well as eliminating certain 
positions made redundant as a result of our site consolidations and a realignment of our commercial sales team. 

27 

  
  
  
  
 
  
  
  
   
   
  
   
   
  
  
  
  
  
  
  
  
  
  
  
  
 
 
Amortization of intangible assets 

Amortization of intangible asset expenses was $2.7 million for the year ended December 31, 2016 compared with $2.8 

million for the year ended December 31, 2015. 

Impairment charges 

During the third quarter of 2016, we initiated plans to sell the operations of AHN. As a result of initiating the plan to 
sell  the  operations  of  AHN,  we  evaluated  the  long-lived  assets  for  impairment,  pursuant  to  ASC  360-10.  Based  on  the 
resulting impairment analysis, we recognized an impairment charge of $0.7 million for the year ended December 31, 2016. 

Loss on sale of AHN 

The loss on sale of AHN was $1.2 million for the year ended December 31, 2016. During the fourth quarter of 2016, 
we concluded the sale of AHN. Upon the closing of the transaction, we recorded a loss on sale of $1.2 million for the year 
ended December 31, 2016. 

Other expense, net 

Other expense, net, was $0.1 million and $1.9 million for the years ended December 31, 2016 and 2015, respectively. 
Included in other expense, net for the year ended December 31, 2016 was interest expense of $0.6 million. For the year ended 
December 31, 2015 other expense, net included $0.9 million of interest expense and $1.2 million of acquisition related costs, 
including due diligence and deal investigative activities. The decrease in other expense, net was primarily due to the decrease 
in  acquisition  related  costs  and  currency  exchange  rate  fluctuations.  Currency  exchange  rate  fluctuations  included  as  a 
component of net (loss) income resulted in approximately $0.7 million in currency gains during the year ended December 
31, 2016, compared to $0.2 million in currency gains during the year ended December 31, 2015. 

Income taxes 

Income tax expense was approximately $1.2 million and $15.4 million for the years ended December 31, 2016 and 
2015,  respectively.  The decrease  in  income  tax  expense year  over  year  was primarily  attributable  to  the  recognition of  a 
valuation allowance on U.S. deferred tax assets in 2015. During the year ended December 31, 2015, we determined that it 
was more likely than not that our U.S. deferred tax assets would not be realized and therefore recorded a net increase to the 
valuation  allowance  of  $16.4  million  to  offset  U.S.  deferred  tax  assets  net  of  deferred  tax  liabilities  except  for  certain 
indefinite-lived intangible assets. This decision was based on all available evidence. 

Liquidity and Capital Resources  

Historically, we have financed our business through cash provided by operating activities, the issuance of common 
stock,  and  bank  borrowings.  Our  liquidity  requirements  arise  primarily  from  investing  activities,  including  funding  of 
acquisitions, and other capital expenditures. On October 26, 2016, we sold the operations of AHN and received approximately 
$1.4 million, net of cash on hand. Subsequent to December 31, 2017, we sold the operations of Denville Scientific, Inc. and 
received approximately $17.0 million. Simultaneously, we retired our existing debt balances of approximately $11.9 million. 
On January 31, 2018, we entered into a financing agreement which comprised of a $64.0 million term loan and up to a $25.0 
million line of credit. Finally, on January 31, 2018, we acquired Data Sciences International, Inc. for $70.0 million. 

As of December 31, 2017, we held cash and cash equivalents of $5.7 million, compared with $5.6 million at December 
31,  2016.  As  of  December  31,  2017  and  December  31,  2016,  we  had  $11.7  million  and  $13.7  million,  respectively,  of 
borrowings outstanding under our credit facility. Total debt, net of cash and cash equivalents was $6.0 million at December 
31, 2017, compared to $8.1 million at December 31, 2016. In addition, we had an underfunded United Kingdom pension 
liability of approximately $1.2 million and $3.0 million at December 31, 2017 and December 31, 2016, respectively. 

As of December 31, 2017 and December 31, 2016, cash and cash equivalents held by our foreign subsidiaries was $4.8 
million and $4.5 million, respectively. Funds held by our foreign subsidiaries are not available for domestic operations unless 
the funds are repatriated. At December 31, 2017, we changed our indefinite reinvestment assertion to provide that all foreign 
earnings above the level required for local operating expenses would be repatriated to the U.S. in tax years after 2017. At 
December 31, 2017, as we were considering a potential U.S. acquisition, we changed our assertion and it was anticipated that 
U.S. needs would require repatriation of all foreign subsidiaries’ earnings rather than just France and Canada. As a result of 
the  Tax  Act,  all  prior  unremitted  earnings  are  deemed  paid  and  included  in  the  current  provision  under  the  one-time 
repatriation tax calculation. Prior to 2017, this modified assertion only applied to our subsidiaries in France and Canada. 

28 

  
  
  
  
  
  
  
  
  
  
  
  
 
Therefore,  no  tax  liability  other  than  withholding  tax  has  been  accrued  at  December  31,  2017  for  these  anticipated 
repatriations. 

Condensed Cash Flow Statements 
(unaudited) 

2017 

Year Ended December 31, 
2016 
(in thousands) 

2015 

Cash flows from operations: 

Net loss ...........................................................................................    $ 
Changes in assets and liabilities .....................................................      
Other adjustments to operating cash flows .....................................      
Net cash provided by operating activities ...................................      

Investing activities: 

Additions to property, plant and equipment ...................................      
Acquisitions, net of cash acquired ..................................................      
Dispositions, net of cash on hand ...................................................      
Other investing activities ................................................................      
Net cash used by investing activities ..........................................      

(865)   $
(3,811)     
5,733      
1,057      

(890)     
-      
-      
(27)     
(917)     

Financing activities: 

Net repayments of debt ...................................................................      
Other financing activities ...............................................................      
Net cash used by financing activities .........................................      

(1,952)     
160      
(1,792)     

(4,307 )   $
(41 )     
9,731       
5,383       

(1,445 )     
-       
1,417       
(34 )     
(62 )     

(5,050 )     
182       
(4,868 )     

(19,039) 
(2,719) 
22,463  
705  

(2,960) 
(4,545) 
-  
(12) 
(7,517) 

(2,550) 
2,010  
(540) 

Effect of exchange rate changes on cash ............................................      

1,789      

(1,601 )     

(38) 

Increase (decrease) in cash and cash equivalents ...............................    $ 

137    $

(1,148 )   $

(7,390) 

Our operating activities provided cash of $1.1 million, $5.4 million and $0.7 million for the years ended December 31, 
2017, 2016 and 2015, respectively. The decrease in cash flows from operations in 2017 compared to 2016 was primarily due 
to larger outflows due to working capital changes in 2017 as well as larger noncash charges in 2016. The increase in cash 
flows from operations in 2016 compared to 2015 was primarily due to a lower net loss with higher noncash charges in 2016, 
and a decrease in inventory and receivables as compared to 2015. 

Our investing activities used cash of $0.9 million during the year ended December 31, 2017, $0.1 million for the year 
ended December 31, 2016, and $7.5 million for the year ended December 31, 2015. Investing activities during 2017, 2016 
and 2015 included purchases of property, plant and equipment, proceeds from the sale of property, plant and equipment and 
expenditures for our catalogs. In addition, investing activities in 2016 included proceeds from the disposition of AHN, net of 
cash on hand, of $1.4 million. In January 2015, we acquired HEKA for approximately $4.5 million, net of cash acquired. 
During  2017,  2016  and  2015,  capital  expenditures  were  $0.9  million,  $1.4  million  and  $3.0  million,  respectively.  The 
increases in capital expenditures in 2016 over 2015 was due to the investment in implementing a new Enterprise Resource 
Planning (ERP) platform. Capital expenditure decreased in 2017, as a significant amount of the upfront ERP costs had already 
been incurred. 

Our financing activities have historically consisted of borrowings and repayments under our revolving credit facility 
and term loans, payments of debt issuance costs, and the issuance of common stock. During the years ended December 31, 
2017, 2016 and 2015, financing activities used cash of $1.8 million, $4.9 million and $0.5 million , respectively. During the 
year ended December 31, 2017, we borrowed $2.8 million under our credit facility, repaid $4.7 million of debt under our 
credit facility and term loans and ended the year with $11.7 million of borrowings. Net proceeds from the issuance of common 
stock for the year ended December 31, 2017 were $0.2 million, which related to the exercise of stock options and the employee 
stock purchase plan. During the year ended December 31, 2016, we borrowed $4.0 million under our credit facility, repaid 
$9.0 million of debt under our credit facility and term loans and ended the year with $13.7 million of borrowings. Net proceeds 
from  the  issuance  of  common  stock  for  2016  were  $0.2  million,  which  related  to  the  exercise  of  stock  options  and  the 
employee stock purchase plan. During the year ended December 31, 2015, we borrowed $5.8 million under our credit facility, 
repaid $8.4 million of debt under our credit facility and term loans and ended the year with $18.9 million of borrowings. Net 

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proceeds from the issuance of common stock for 2015 were $2.0 million, which related to the exercise of stock options and 
the employee stock purchase plan. 

Borrowing Arrangements  

On August 7, 2009, we entered into an Amended and Restated Revolving Credit Loan Agreement related to a $20.0 
million revolving credit facility with Bank of America, as agent, and Bank of America and Brown Brothers Harriman & Co 
as lenders (as amended, the 2009 Credit Agreement). On March 29, 2013, we entered into a Second Amended and Restated 
Revolving Credit Agreement (as amended, the 2013 Credit Agreement) with Bank of America, as agent, and Bank of America 
and Brown Brothers Harriman & Co, as lenders that amended and restated the 2009 Credit Agreement. Between September 
2011 and May 2017, we entered into a series of amendments that among other things did the following: 

• 

• 

• 

• 

• 

• 

• 

on September 30, 2011, reduced interest rates to the London Interbank Offered Rate plus 3.0%; 

on March 29, 2013, converted existing loan advances into a term loan in the principal amount of $15.0 million
(the 2013 Term Loan), provided a revolving credit facility in the maximum principal amount of $25.0 million
(the 2013 Revolving Line) and a delayed draw term loan (the 2013 DDTL) of up to $15.0 million; 

on October 31, 2013, reduced the 2013 DDTL from up to $15.0 million to up to $10.0 million; 

on April 24, 2015, extended the maturity date of the 2013 Revolving Line to March 29, 2018 and reduced the
interest rates on the 2013 Revolving Line, 2013 Term Loan and 2013 DDTL; 

on June 30, 2015, amended its quarterly minimum fixed charge coverage financial covenant; 

on March 9, 2016, amended the principal payment amortization of the 2013 Term Loan and 2013 DDTL to
five years, as well as amended its quarterly minimum fixed charge coverage financial covenant; and 

on May 2, 2017, entered into a Third Amended and Restated Revolving Credit Agreement (as amended, the
Credit Agreement) with Bank of America, as agent, and Bank of America and Brown Brothers Harriman &
Co, as lenders that amended and restated the 2013 Credit Agreement. 

The  Credit  Agreement  was  entered  into  to,  among  other  things,  consolidate,  combine  and  restate  the  outstanding 
indebtedness, on the date of the Credit Agreement, into a term loan (the Term Loan) in the principal amount of $14.0 million, 
and also provide for a $25.0 million revolving line of credit (the Revolving Line). The Term Loan and the Revolving Line 
each have a maturity date of May 1, 2022. Borrowings under the Term Loan accrue interest at a rate based on either the 
effective LIBOR for certain interest periods selected by us, or a daily floating rate based on the BBA LIBOR as published by 
Reuters (or other commercially available source providing quotations of BBA LIBOR), plus in either case, a margin of 2.75%. 
Additionally, the Revolving Line accrues interest at a rate based on either the effective LIBOR for certain interest periods 
selected by us, or a daily floating rate based on the BBA LIBOR, plus in either case, a margin of 2.25%.  

The Term Loan and loans under the Revolving Line evidenced by the Credit Agreement, or the Loans, are guaranteed 
by all of our direct and indirect domestic subsidiaries, and secured by substantially all of the assets of the Company and the 
guarantors. The Loans are subject to restrictive covenants under the Credit Agreement, and financial covenants that require 
us and our subsidiaries to maintain certain financial ratios on a consolidated basis, including a maximum leverage, minimum 
fixed charge coverage and minimum working capital. Prepayment of the Loans is allowed by the Credit Agreement at any 
time during the terms of the Loans. The Loans also contain limitations on our ability to incur additional indebtedness and 
requires lender approval for acquisitions funded with cash, promissory notes and/or other consideration in excess of $6.0 
million and for acquisitions funded solely with equity in excess of $10.0 million. 

As  of  December  31,  2017  and  December  31,  2016,  we  had  borrowings  of  $11.7  million  and  $13.7  million,  net  of 
deferred financing costs, respectively, outstanding under our Credit Agreement. The carrying value of the debt approximates 
fair  value  because  the  interest  rate  under  the  obligation  approximates  market  rates  of  interest  available  to  us  for  similar 
instruments. 

As of December 31, 2017, the weighted effective interest rates, net of the impact of our interest rate swaps, on our 

Term Loan, was 4.61%. 

On January 22, 2018, in connection with the sale of Denville, we terminated the Credit Agreement. All outstanding 
amounts under the agreement were repaid in full using a portion of the proceeds of the Denville sale. At the time of repayment, 
there was approximately $11.9 million outstanding. 

30 

  
  
  
  
  
  
  
On January 31, 2018, we acquired all of the issued and outstanding shares of Data Sciences International, Inc. (DSI), 
a Delaware corporation for approximately  $70.0 million. We funded the acquisition from our existing cash balances, the 
proceeds of the Denville transaction and the proceeds of the Financing Agreement discussed below. 

Additionally,  on  January  31,  2018,  we  entered  into  a  financing  agreement  by  and  among  us  and  certain  of  our 
subsidiaries, as borrowers (collectively, the Borrower), certain of our subsidiaries, as guarantors, various lenders from time 
to time party thereto (the Lenders), and Cerberus Business Finance, LLC, as collateral agent and administrative agent for the 
Lenders (the Financing Agreement). 

The Financing Agreement provides for senior secured credit facilities (the Senior Secured Credit Facilities) comprised 
of a $64.0 million term loan and up to a $25.0 million revolving line of credit. The proceeds of the term loan and $4.8 million 
of advances under the revolving line of credit were used to fund a portion of the DSI acquisition, and to pay fees and expenses 
related thereto and the closing of the Senior Secured Credit Facilities. In addition, the revolving facility is available for use 
by us and our subsidiaries for general corporate and working capital needs, and other purposes to the extent permitted by the 
Financing Agreement. The Senior Secured Credit Facilities have a maturity of five years. At the closing date of the Financing 
Agreement, we had approximately $14.5 million of available borrowing capacity under the revolving line of credit. 

Commencing on March 31, 2018, the outstanding term loans will amortize in equal quarterly installments equal to 
$0.4 million per quarter on such date and during each of the next three quarters thereafter, $0.6 million per quarter during the 
next four quarters thereafter and $0.8 million per quarter thereafter, with a balloon payment at maturity. 

The obligations of the Borrower under the Senior Secured Credit Facilities are unconditionally guaranteed by us and 
certain of our existing and subsequently acquired or organized subsidiaries. The Senior Secured Credit Facilities and related 
guarantees are secured on a first-priority basis (subject to certain liens permitted under the Financing Agreement) by a lien 
on substantially all the tangible and intangible assets of the Borrower and the subsidiary guarantors, including all of the capital 
stock held by such obligors (subject to a 65% limitation on pledges of capital stock of foreign subsidiaries), subject to certain 
exceptions. 

Interest  on  all  loans  under  the  Senior  Secured  Credit  Facilities  is  paid  monthly.  Borrowings  under  the  Financing 
Agreement accrue interest at a per annum rate equal to, at our option, a base rate plus 4.75% or a LIBOR rate plus 6.25%. 
The loans are also subject to a 1.25% interest rate floor for LIBOR loans and a 4.25% interest rate floor for base rate loans. 

As a result of terminating the Credit Agreement, we unwound our previously existing swap agreement and received 
an immaterial amount of proceeds. On February 16, 2018, we entered into a new interest rate swap contract with PNC bank 
with a notional amount of $36.0 million and a termination date of January 31, 2023 in order to hedge the risk of changes in 
the  effective  benchmark  interest  rate  (LIBOR)  associated  with  the  Financing  Agreement.  The  swap  contract  converted 
specific variable-rate debt into fixed-rate debt and fixed the LIBOR rate associated with a portion of the term loan under the 
Financing Agreement at 2.72%. 

The Financing Agreement contains customary representations and warranties and affirmative covenants applicable us 
and our subsidiaries and also contains certain restrictive covenants, including, among others, limitations on the incurrence of 
additional debt, liens on property, acquisitions and investments, loans and guarantees, mergers, consolidations, liquidations 
and dissolutions, asset sales, dividends and other payments in respect of the Company’s capital stock, prepayments of certain 
debt,  transactions  with  affiliates  and  modifications  of  organizational  documents,  material  contracts,  affiliated  practice 
agreements and certain debt agreements. The Financing Agreement also contains customary events of default. 

Our forecast of the period of time through which our financial resources will be adequate to support our operations is 
a forward-looking statement that involves risks and uncertainties, and actual results could vary as a result of a number of 
factors. Based on our current operations and current operating plans, we expect that our available cash, cash generated from 
current operations and debt capacity will be sufficient to finance current operations, any potential future acquisitions and 
capital expenditures for the next 12 months and beyond. This may involve incurring additional debt or raising equity capital 
for our business. Additional capital raising activities will dilute the ownership interests of existing stockholders to the extent 
we raise capital by issuing equity securities and we cannot guarantee that we will be successful in raising additional capital 
on favorable terms or at all. 

31 

 
 
Contractual Obligations 

The following schedule represents our contractual obligations for our continuing operations, excluding interest, as of 

December 31, 2017. 

   Total      

     2023 and   
2018       2019       2020       2021       2022       Beyond   

-  
Bank credit facility and notes payable ............    $11,899      $11,899      $
-     $ 
Operating leases .............................................       8,974         1,744         1,657         1,501         1,110        1,089       
1,873  
Total ...............................................................    $20,873      $13,643      $ 1,657      $ 1,501      $ 1,110     $ 1,089     $  1,873  

-     $ 

(in thousands) 
-      $ 
-      $

As previously noted, we sold Denville in January 2018, and accordingly the table above excludes its future payments 
under operating leases. Additionally, we acquired DSI in January 2018, and as such the table above, which is as of December 
31, 2017, excludes its future operating payments under its operating lease. 

We have a liability at December 31, 2017 and 2016 of $0.3 million and $0.4 million, respectively for uncertain tax 
positions taken in an income tax return. We do not know the ultimate resolution of these uncertain tax positions and as such, 
do not know the ultimate timing of payments, if any, related to this liability. Accordingly, this amount is not included in the 
above table. 

We have an underfunded United Kingdom pension liability of $1.2 million and $3.0 million as of December 31, 2017 
and 2016, respectively, which is recognized as part of the "Other long term liabilities" line item in our consolidated balance 
sheets. Since we do not know the ultimate timing of payments related to this liability, this amount has not been included in 
the above table. 

Critical Accounting Policies  

We believe that our critical accounting policies are as follows: 

• 

• 

• 

• 

• 

• 

revenue recognition; 

accounting for income taxes; 

inventory; 

valuation of identifiable intangible assets in business combinations; 

valuation of long-lived and intangible assets and goodwill; and 

stock-based compensation. 

Revenue recognition.     We follow the provisions of FASB ASC 605, “Revenue Recognition”. We recognize revenue 
of products when persuasive evidence of a sales arrangement exists, the price to the buyer is fixed or determinable, delivery 
has occurred, and collectability of the sales price is reasonably assured. Sales of some of our products include provisions to 
provide additional services such as installation and training. Revenues on these products are recognized when the additional 
services  have  been  performed.  Service  agreements  on  our  equipment  are  typically  sold  separately  from  the  sale  of  the 
equipment. Revenues on these service agreements are recognized ratably over the life of the agreement, typically one year, 
in accordance with the provisions of FASB ASC 605-20, “Revenue Recognition—Services”. 

We account for shipping and handling fees and costs in accordance with the provisions of FASB ASC 605-45-45, 
“Revenue Recognition—Principal Agent Considerations”, which requires all amounts charged to customers for shipping and 
handling to be classified as revenues. Our costs incurred related to shipping and handling are classified as cost of product 
revenues. Warranties and product returns are estimated and accrued for at the time sales are recorded. We have no obligations 
to customers after the date products are shipped or installed, if applicable, other than pursuant to warranty obligations and 
service  or  maintenance  contracts.  We  provide  for  the  estimated  amount  of  future  returns  upon  shipment  of  products  or 
installation,  if  applicable,  based  on  historical  experience.  Historically,  product  returns  and  warranty  costs  have  not  been 
significant, and they have been within our expectations and the provisions established, however, there is no assurance that 
we  will  continue  to  experience  the  same  return  rates  and  warranty  repair  costs  that  we  have  in  the  past.  Any  significant 
increase in product return rates or a significant increase in the cost to repair our products could have a material adverse impact 
on our operating results for the period or periods in which such returns or increased costs materialize. 

32 

  
     
       
       
       
       
       
  
  
  
  
  
  
  
  
  
  
We make estimates evaluating our allowance for doubtful accounts. On an ongoing basis, we monitor collections and 
payments from our customers and maintain a provision for estimated credit losses based upon our historical experience and 
any specific customer collection issues that we have identified. Historically, such credit losses have not been significant, and 
they have been within our expectations and the provisions established, however, there is no assurance that we will continue 
to experience the same credit loss rates that we have in the past. A significant change in the liquidity or financial position of 
our customers could have a material adverse impact on the collectability of our accounts receivable and our future operating 
results. 

Accounting for income taxes.     We determine our annual income tax provision in each of the jurisdictions in which 
we operate. This involves determining our current and deferred income tax expense that reflects accounting for differences 
between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases. The future 
tax  consequences  attributable  to  these  differences  result  in  deferred  tax  assets  and  liabilities,  which  are  included  in  our 
consolidated balance sheets. We assess the recoverability of the deferred tax assets by considering whether it is more likely 
than not that some portion or all of the deferred tax assets will not be realized. To the extent we believe that recovery does 
not meet this “more likely than not” standard as required in FASB ASC 740, “Income Taxes”, we must establish a valuation 
allowance. If a valuation allowance is established, increased or decreased in a period, we allocate the related income tax 
expense or benefit to income from continuing operations in the consolidated statement of operations. 

Management’s judgment and estimates are required in determining our income tax provision, deferred tax assets and 
liabilities and any valuation allowance recorded against deferred tax assets. We review the recoverability of deferred tax 
assets  during  each  reporting  period  by  reviewing  estimates  of  future  taxable  income,  future  reversals  of  existing  taxable 
temporary differences, and tax planning strategies that would, if necessary, be implemented to realize the benefit of a deferred 
tax asset before expiration. Due to our three year cumulative loss position, we concluded that a full valuation allowance was 
required to offset most U.S. deferred tax assets, net of deferred tax liabilities except deferred tax liabilities related to indefinite 
lived intangible assets. At December 31, 2017, we have a valuation allowance of $11.4 million, of which $10.6 million relates 
to our U.S. deferred tax assets. The remainder relates to deferred tax assets in certain foreign jurisdictions. 

We assess tax positions taken on tax returns, including recognition of potential interest and penalties, in accordance 
with the recognition thresholds and measurement attributes outlined in FASB ASC 740. Interest and penalties recognized, if 
any, would be classified as a component of income tax expense. 

Inventory.      We  value  our  inventory  at  the  lower  of  the  actual  cost  to  purchase  (first-in,  first-out  method)  and/or 
manufacture the inventory or the current estimated market value of the inventory. We regularly review inventory quantities 
on hand and record a provision to write down excess and obsolete inventory to its estimated net realizable value if less than 
cost,  based  primarily  on  historical  inventory  usage  and  estimated  forecast  of  product  demand.  Since  forecasted  product 
demand quite often is a function of previous and current demand, a significant decrease in demand could result in an increase 
in the charges for excess inventory quantities on hand. In addition, our industry is subject to technological change and new 
product development, and technological advances could result in an increase in the amount of obsolete inventory quantities 
on hand. Therefore, any significant unanticipated changes in demand or technological developments could have a significant 
adverse impact on the value of our inventory and our reported operating results. 

Valuation of identifiable intangible assets acquired in business combinations.    The determination of the fair value of 
intangible assets, which represents a significant portion of the purchase price in our acquisitions, requires the use of significant 
judgment with regard to (i) the fair value; and (ii) whether such intangibles are amortizable or not amortizable and, if the 
former, the period and the method by which the intangibles asset will be amortized. We estimate the fair value of acquisition-
related intangible assets principally based on projections of cash flows that will arise from identifiable assets of acquired 
businesses. The projected cash flows are discounted to determine the present value of the assets at the dates of acquisitions. 
At  December  31,  2017,  amortizable  intangible  assets  include  existing  technology,  trade  names,  distribution  agreements, 
customer relationships and patents. These amortizable intangible assets are amortized on a straight-line basis over 7 to 15 
years, 10 to 15 years, 4 to 5 years, 5 to 15 years and 5 to 15 years, respectively. 

Valuation of long-lived and intangible assets.     In accordance with the provisions of FASB ASC 360, “Property, 
Plant and Equipment”, we assess the value of identifiable intangibles with finite lives and long-lived assets for impairment 
whenever events or changes in circumstances indicate that the carrying value may not be recoverable. Factors we consider 
important which could trigger an impairment review include the following: significant underperformance relative to expected 
historical or projected future operating results; significant changes in the manner of our use of the acquired assets or the 
strategy for our overall business; significant negative industry or economic trends; significant changes in who our competitors 
are and what they do; significant changes in our relationship with our distributors; significant decline in our stock price for a 
sustained period; and our market capitalization relative to net book value. 

33 

If we were to determine that the value of long-lived assets and identifiable intangible assets with finite lives was not 
recoverable based on the existence of one or more of the aforementioned factors, then the recoverability of those assets to be 
held and used would be measured by a comparison of the carrying amount of those assets to undiscounted future net cash 
flows before tax effects expected to be generated by those assets. If such assets are considered to be impaired, the impairment 
to be recognized would be measured by the amount by which the carrying value of the assets exceeds the fair value of the 
assets. 

As a result of our initiation of plans to sell the operations of AHN during the third quarter of 2016, we conducted an 
evaluation of AHN’s assets for impairment. Based on this evaluation, we recognized an impairment charge of $0.7 million 
on its long-lived assets. 

Goodwill  and  Other Intangible  Assets.     FASB  ASC  350, “Intangibles-Goodwill  and  Others”  addresses  financial 
accounting and reporting for acquired goodwill and other intangible assets. Among other things, FASB ASC 350 requires 
that  goodwill  and  intangible  assets  with  indefinite  useful  lives  no  longer  be  amortized,  but  rather  tested  annually  for 
impairment or more frequently if events or circumstances indicate that there may be impairment. Goodwill is also subject to 
an annual impairment test, or more frequently, if indicators of potential impairment arise. ASU 2011-08 intends to simplify 
goodwill impairment testing by permitting an assessment of qualitative factors to determine when events and circumstances 
lead to the conclusion that it is necessary to perform the two-step goodwill impairment test required under ASC 350. The 
two-step goodwill impairment test consists of a comparison of the fair value of our reporting units with their carrying amount. 
If the carrying amount exceeds its fair value, we are required to perform the second step of the impairment test, as this is an 
indication  that  goodwill  may  be  impaired.  The  impairment  loss  is  measured  by  comparing  the  implied  fair  value  of  the 
reporting unit’s goodwill with its carrying amount. If the carrying amount exceeds the implied fair value, an impairment loss 
shall be recognized in an amount equal to the excess. After an impairment loss is recognized, the adjusted carrying amount 
of the intangible asset shall be its new accounting basis. Subsequent reversal of a previously recognized impairment loss is 
prohibited. For unamortizable intangible assets, if the carrying amount were to exceed the fair value of the asset we would 
write down the unamortizable intangible asset to fair value. 

For the purpose of our goodwill analysis, we have one reporting unit. We conducted our annual impairment analysis 
in  the  fourth  quarter  of  fiscal  year  2017.  The  determination  of  the  fair  value  of  the  reporting  unit  requires  us  to  make  a 
significant estimate on control premiums appropriate of industries in which we compete. We compared our carrying value to 
our overall market capitalization. 

The  results  of  our  test  for  goodwill  impairment  showed  that  the  estimated  fair  value  of  our  business  substantially 
exceeded its carrying value. We concluded that none of our goodwill was impaired.  We also concluded that the fair value of 
the unamortized intangible assets significantly exceeds the carrying amounts. 

Stock-based compensation.     We account for stock-based payment awards in accordance with the provisions of FASB 
ASC 718, “Compensation—Stock Compensation”, which requires us to recognize compensation expense for all stock-based 
payment awards made to employees and directors including stock options, restricted stock units, restricted stock units with a 
market condition and employee stock purchases related to our Employee Stock Purchase Plan (as amended, ESPP). We issue 
new shares upon stock option exercises, upon the vesting of restricted stock units and restricted stock units with a market 
condition, and under our ESPP. 

FASB ASC 718 requires companies to estimate the fair value of stock-based payment awards on the date of grant 
using an option-pricing model. The value of the award that vests is recognized as expense over the requisite service periods 
in our consolidated statement of operations. We adopted ASU 2016-09 as of January 1, 2017. As a result of this adoption, we 
have elected as an accounting policy to account for forfeitures for service based awards as they occur, with no adjustment for 
estimated forfeitures. 

We  value  stock-based  payment  awards,  except  restricted  stock  awards,  at  the  grant  date  using  the  Black-Scholes 
option-pricing  model.  We  value  the  restricted  stock  units  with  a  market  condition  at  the  grant  date  using  a  Monte-Carlo 
valuation simulation. Our determination of fair value of stock-based payment awards on the date of grant using an option-
pricing model or Monte-Carlo valuation simulation is affected by our stock price as well as assumptions regarding a number 
of highly complex and subjective variables. These variables include, but are not limited to our expected stock price volatility 
over the term of the awards and actual and projected stock option exercise behaviors. 

The fair value of restricted stock units are based on the market price of our common stock on the date of grant and are 
recorded as compensation expense ratably over the applicable service period, which ranges from one to four years. Unvested 
restricted stock units are forfeited in the event of termination of employment or engagement with our Company. 

We record stock compensation expense on a straight-line basis over the requisite service period for all awards granted. 

34 

Impact of Foreign Currencies  

Our international operations in some instances operate in a natural hedge as we sell our products in many countries and 
a substantial portion of our revenues, costs and expenses are denominated in foreign currencies, especially the British pound 
sterling, the Euro, the Canadian dollar and the Swedish krona. 

For the year ended December 31, 2017, the U.S dollar’s strengthening in relation to those currencies resulted in an 
unfavorable translation effect on our consolidated revenues and a neutral effect on our consolidated net loss. Changes in 
foreign currency exchange rates resulted in an unfavorable effect on revenues of approximately $0.3 million and a favorable 
effect on expenses of approximately $0.3 million. During 2016, the U.S dollar’s strengthening in relation to those currencies 
resulted in an unfavorable translation effect on our consolidated revenues and our consolidated net loss. Changes in foreign 
currency exchange rates resulted in an unfavorable effect on revenues of approximately $2.1 million and a favorable effect 
on  expenses  of  approximately  $1.9  million.  Similarly,  during  2015,  the  U.S  dollar’s  strengthening  in  relation  to  those 
currencies resulted in an unfavorable translation effect on our consolidated revenues and our net income. Changes in foreign 
currency exchange rates resulted in an unfavorable effect on revenues of $4.0 million and a favorable effect on expenses of 
$3.6 million. 

The gain associated with the translation of foreign equity into U.S. dollars included as a component of comprehensive 
income (loss) for the year ended December 31, 2017, was approximately $4.4 million, compared to losses of $4.6 million 
and $4.9 million for the years ended December 31, 2016 and 2015, respectively. 

In addition, currency exchange rate fluctuations included as a component of net loss resulted in currency losses of 
approximately $0.5 million during the year ended December 31, 2017, compared to currency gains of approximately $0.7 
million and $0.2 million during the years ended December 31, 2016 and 2015, respectively. 

Recently Issued Accounting Pronouncements  

In  February  2016,  the  FASB  issued  ASU  2016-02,  Leases,  which  is  intended  to  improve  financial  reporting  about 
leasing transactions. The update requires a lessee to record on the balance sheet the assets and liabilities for the rights and 
obligations  created  by  lease  terms  of  more  than  12 months.  The  update  is  effective  for  fiscal  years  beginning  after 
December 15, 2018. We have commenced the process of evaluating the requirements of the standard as well as collecting 
information on all our leases. We have not yet concluded on the impact of the adoption on our consolidated financial position, 
results of operations and cash flows, however, assets and liabilities will increase upon adoption for right-of-use assets and 
lease  liabilities.   Our  future  commitments  under  lease  obligations  are  summarized  under  the  “Contractual  Obligations” 
heading above. 

In June 2016, the FASB issued ASU 2016-13, Financial Instruments – Credit Losses (Topic 326), Measurement of 
credit losses on Financial Instruments. The update amends the FASB’s guidance on the impairment of financial instruments. 
The ASU adds to U.S. GAAP an impairment model (known as the current expected credit loss (CECL) model) that is based 
on expected losses rather than incurred losses. Under the new guidance, an entity recognizes as an allowance its estimate of 
expected credit losses, which the FASB believes will result in more timely recognition of such losses. The ASU is effective 
for fiscal years beginning after December 15, 2019, including interim periods within those fiscal years. We are evaluating the 
impact of ASU 2016-13 on our consolidated financial statements. 

In  August  2017,  the  FASB  issued  ASU  2017-12, Derivatives  and  Hedging  (Topic  815) which  amends  the  hedge 
accounting  recognition  and presentation  requirements  in ASC  815.  The  Board’s objectives  in  issuing  the  ASU  are  to  (1) 
improve the transparency and understandability of information conveyed to financial statement users about an entity’s risk 
management activities by better aligning the entity’s financial reporting for hedging relationships with those risk management 
activities  and  (2)  reduce  the  complexity  of  and  simplify  the  application  of  hedge  accounting  by  preparers.  The  ASU  is 
effective  for  annual  reporting  periods,  including  interim  periods  within  those  annual  reporting  periods,  beginning  after 
December 15, 2018. Early adoption is permitted, including adoption in any interim period. We are evaluating the requirements 
of this guidance and have not yet determined the impact of the adoption on our consolidated financial position, results of 
operations and cash flows. 

Recently Adopted Accounting Pronouncements 

Adopted in 2017  

In March 2016, the FASB issued ASU 2016-09, Compensation – Stock Compensation (Topic 718): Improvements to 
Employee  Share-Based  Payment  Accounting,  which  simplifies  the  accounting  for  share-based  payment  transactions, 

35 

including  the  income  tax  consequences,  classification  of  awards  as  either  equity  or  liabilities  and  classification  on  the 
statement of cash flows. 

The standard requires an entity to recognize all excess tax benefits and tax deficiencies as income tax benefit or expense 
in the income statement as discrete items in the reporting period in which they occur, and such tax benefits and tax deficiencies 
are not included in the estimate of an entity’s annual effective tax rate, applied on a prospective basis. Further, the standard 
eliminates the requirement to defer the recognition of excess tax benefits until the benefit is realized through a reduction to 
taxes payable. All excess tax benefits previously unrecognized, along with any valuation allowance, should be recognized on 
a modified retrospective basis as a cumulative adjustment to retained earnings as of the date of adoption. Under ASU 2016-
09, an entity that applies the treasury stock method in calculating diluted earnings per share is required to exclude excess tax 
benefits  and  deficiencies  from  the  calculation  of  assumed  proceeds  since  such  amounts  are  recognized  in  the  income 
statement. Excess tax benefits should also be classified as operating activities in the same manner as other cash flows related 
to income taxes on the statement of cash flows, as such excess tax benefits no longer represent financing activities since they 
are recognized in the income statement, and should be applied prospectively or retrospectively to all periods presented. 

We  adopted  ASU  2016-09  as  of  January  1,  2017.  We  recorded  a  cumulative  increase  in  retained  earnings  of  $0.5 
million at the beginning of the first quarter of 2017 with a corresponding increase in deferred tax assets related to the prior 
years’ unrecognized excess tax benefits. An equal amount of valuation allowance was also recorded against these deferred 
tax assets with a corresponding decrease to retained earnings resulting in no net impact to retained earnings and deferred tax 
assets. In addition, tax deficiencies related to vested restricted stock units and canceled stock options during the year ended 
December 31, 2017 have been recognized in the current period’s income statement. 

ASU 2016-09 also allows an entity to elect as an accounting policy either to continue to estimate the total number of 
awards for which the requisite service period will not be rendered or to account for forfeitures for service based awards as 
they occur. An entity that elects to account for forfeitures as they occur should apply the accounting change on a modified 
retrospective  basis  as  a  cumulative  effect  adjustment  to  retained  earnings  as  of  the  date  of  adoption.  We  elected  as  an 
accounting policy to account for forfeitures for service based awards as they occur, and as a result, we recorded a cumulative 
effect adjustment of $0.1 million to reduce retained earnings with a corresponding increase in additional paid in capital related 
to the prior years’ stock-based compensation expense as required under the modified retrospective approach. The tax effect 
of this adjustment, which included the impact of a valuation allowance was immaterial. 

Adopted in 2018 

In May 2014, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) 2014-
09, Revenue from Contracts with Customers, a new accounting standard that provides for a comprehensive model to use in 
the accounting for revenue arising from contracts with customers that will replace most existing revenue recognition guidance 
within generally accepted accounting principles in the United States. Under this standard, revenue will be recognized to depict 
the transfer of promised goods or services to customers in an amount that reflects the consideration to which we expect to be 
entitled in exchange for those goods or services. 

We have completed the process of evaluating the impact of the new standard on its consolidated financial position, 
results  of  operations  and  cash  flows.  We  adopted  this  standard  as  of  January  1,  2018  using  the  modified  retrospective 
approach. As part of the implementation of the standard, we identified our significant revenue streams, which currently consist 
primarily of product revenue transactions, and to a lesser extent, extended warranty transactions on certain product sales, and 
revenues  from  government  contracts.  The  timing  of  recognizing  revenues  for  these  revenue  streams  is  not  expected  to 
materially  change.  Additionally,  no  material  changes  to  business  processes,  systems  and  controls  are  expected.  We  are 
drafting enhanced revenue disclosures which will be presented prospectively starting in the first quarter of 2018. 

In  May  2017,  the  FASB  issued  ASU  2017-09, Stock  compensation  (Topic  718):  Scope  of  modification 
accounting which amends the scope of modification accounting for share-based payment arrangements. The ASU provides 
guidance on the types of changes to the terms or conditions of share-based payment awards to which an entity would be 
required to apply modification accounting under ASC 718. Specifically, an entity would not apply modification accounting 
if  the  fair  value,  vesting  conditions,  and  classification  of  the  awards  are  the  same  immediately  before  and  after  the 
modification. The ASU  is  effective  for annual  reporting  periods,  including  interim  periods within  those  annual  reporting 
periods, beginning after December 15, 2017. We adopted this guidance on January 1, 2018, and the new standard did not 
have a material impact on our consolidated financial position, results of operations and cash flows.

36 

Item 7A. 

Quantitative and Qualitative Disclosures about Market Risk. 

The  majority  of  our  manufacturing  and  testing  of  products  occurs  in  our  facilities  in  the  United  States,  Germany, 
Sweden and Spain. We sell our products globally through our distributors, direct sales force, websites and catalogs. As a 
result, our financial results are affected by factors such as changes in foreign currency exchange rates and weak economic 
conditions in foreign markets. 

We  collect  amounts  representing  a  substantial  portion  of  our  revenues  and  pay  amounts  representing  a  substantial 
portion of our operating expenses in foreign currencies. As a result, changes in currency exchange rates from time to time 
may affect our operating results. 

We are exposed to market risk from changes in interest rates primarily through our financing activities. As of December 

31, 2017, we had $11.7 million outstanding under our Credit Agreement. 

As noted above under the heading “Borrowing Arrangements”, on May 2, 2017, we entered into the Credit Agreement 
to amend our credit facility with Bank of America, as agent, and Bank of America and Brown Brothers Harriman & Co. as 
lenders. Immediately after entering into this Credit Agreement, we entered into a new interest rate swap contract with Bank 
of America with a notional amount of $14.0 million and a termination date of March 30, 2022 in order to hedge the risk of 
changes  in  the  effective  benchmark  interest  rate  (LIBOR)  associated  with  our  Term  Loan.  The  swap  contract  converted 
specific variable-rate debt into fixed-rate debt and fixed the LIBOR rate associated with the Term Loan at 1.86%. The interest 
rate swap was designated as a cash flow hedge instrument in accordance with ASC 815 “Derivatives and Hedging”. As a 
result of entering into the new interest rate swap contract, we unwound the previous interest rate swap contracts, and received 
an immaterial amount in proceeds. 

As  further  noted  under  the  “Borrowing  Arrangements”  heading,  on  January  22,  2018,  we  terminated  the  Credit 
Agreement, and on January 31, 2018, entered into the Financing Agreement. As a result of terminating the Credit Agreement, 
we unwound our previously existing swap agreement and received an immaterial amount of proceeds. On February 16, 2018, 
we entered into a new interest rate swap contract with PNC bank with a notional amount of $36.0 million and a termination 
date of January 31, 2023 in order to hedge the risk of changes in the effective benchmark interest rate (LIBOR) associated 
with the Financing Agreement. The swap contract converted specific variable-rate debt into fixed-rate debt and fixed the 
LIBOR rate associated with a portion of the term loan under the Financing Agreement at 2.72%. 

As of December 31, 2017, the weighted effective interest rate, net of the impact of our interest rate swap, on our Term 
Loan was 4.61%. Following our entering into the Financing Agreement, our weighted effective interest rate on outstanding 
borrowings was approximately 8.42%. 

Assuming no other changes which would affect the margin of the interest rate, the estimated effect of interest rate 
fluctuations on outstanding borrowings under our Financing Agreement over the next twelve months from January 31, 2018 
is quantified and summarized as follows: 

Interest rates increase by 1% .........................................................................................................................   $ 
Interest rates increase by 2% .........................................................................................................................   $ 

   (in thousands) 
328   
656   

Item 8. 

Financial Statements and Supplementary Data. 

The information required by this item is contained in the consolidated financial statements filed as part of this Annual 

Report on Form 10-K are listed under Item 15 of Part IV below. 

Item 9. 

Changes in and Disagreements with Accountants on Accounting and Financial Disclosure. 

Interest expense 
increase 

None. 

Item 9A. 

Controls and Procedures. 

This Report includes the certifications of our Chief Executive Officer and Chief Financial Officer required by Rule 
13a-14 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). See Exhibits 31.1 and 31.2. This Item 9A 
includes information concerning the controls and control evaluations referred to in those certifications. 

37 

 
  
  
  
  
  
  
  
  
  
  
  
   
  
   
  
   
  
(a)                    Evaluation of Disclosure Controls and Procedures 

Disclosure controls and procedures refer to controls and other procedures designed to ensure that information required 
to be disclosed in the reports we file or submit under the Exchange Act is recorded, processed, summarized and reported, 
within the time periods specified in the rules and forms of the U.S. Securities and Exchange Commission. Disclosure controls 
and  procedures  include,  without  limitation,  controls  and  procedures  designed  to  ensure  that  information  required  to  be 
disclosed  by  us  in  our  reports  that  we  file  or  submit  under  the  Exchange  Act  is  accumulated  and  communicated  to  our 
management, including our Chief Executive Officer and Chief Financial Officer, as appropriate to allow timely decisions 
regarding  our  required  disclosure.  In  designing  and  evaluating  our  disclosure  controls  and  procedures,  our  management 
recognizes  that  any  controls  and  procedures,  no  matter  how  well  designed  and  operated,  can  provide  only  reasonable 
assurance of achieving the desired control objectives, and management was required to apply its judgment in evaluating and 
implementing possible controls and procedures. 

We carried out an evaluation, under the supervision and with the participation our Chief Executive Officer and Chief 
Financial Officer, of the effectiveness of the design and operation of our disclosure controls and procedures (as defined in 
Rules 13a-15(e) and 15d-15(e) under the Exchange Act) as of the end of the period covered in this Report. Based upon the 
evaluation described above, our Chief Executive Officer and Chief Financial Officer have concluded that they believe that 
our  disclosure  controls  and  procedures  were  effective,  as  of  December  31,  2017,  in  providing  reasonable  assurance  that 
information required to be disclosed by us in the reports that we file or submit under the Exchange Act is accumulated and 
communicated  to  our  management,  including  our  Chief  Executive  Officer  and  Chief  Financial  Officer,  to  allow  timely 
decisions  regarding  required  disclosures,  and  is  recorded,  processed,  summarized  and  reported  within  the  time  periods 
specified in the Securities and Exchange Commission’s rules and forms. 

(b)                     Management’s Report on Internal Control Over Financial Reporting 

Our management is responsible for establishing and maintaining adequate internal control over financial reporting (as 
defined in Rules 13a-15(f) and 15d-15(f) under the Exchange Act). Our internal control over financial reporting is a process 
designed  by  and  under  the  supervision  of  our  Chief  Executive  Officer  and  Chief  Financial  Officer  and  effected  by  our 
management  and  other  personnel,  to  provide  reasonable  assurance  regarding  the  reliability  of  financial  reporting  and  the 
preparation  of  consolidated  financial  statements  for  external  purposes  in  accordance  with  generally  accepted  accounting 
principles.  Our  internal  control  over  financial  reporting  includes  those  policies  and  procedures  that  (1)  pertain  to  the 
maintenance  of  records  that,  in  reasonable  detail,  accurately  and  fairly  reflect  transactions  and  dispositions  of  assets,  (2) 
provide  reasonable  assurance  that  transactions  are  recorded  as  necessary  to  permit  preparation  of  consolidated  financial 
statements  for  external  purposes  in  accordance  with  generally  accepted  accounting  principles,  (3)  provide  reasonable 
assurance that receipts and expenditures are being made only in accordance with authorizations of management and directors, 
and (4) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use or disposition 
of assets that could have a material effect on the consolidated financial statements. 

Because of inherent limitations, internal control over financial reporting may not prevent or detect misstatements. It is 
a process that involves human diligence and compliance and is therefore subject to human error and misjudgment. In general, 
evaluations  of  effectiveness  for  future  periods  are  subject  to  risk  as  controls  may  become  inadequate  due  to  changes  in 
conditions or the degree of compliance with key processes or procedures could deteriorate. 

Our management evaluated the effectiveness of our internal control over financial reporting as of December 31, 2017 
using  the  criteria  set  forth  in  Internal  Control  –  Integrated  Framework  (2013)  issued  by  the  Committee  of  Sponsoring 
Organizations of the Treadway Commission (COSO). As a result of that evaluation, management has concluded that our 
internal control over financial reporting was effective as of December 31, 2017. 

The effectiveness of our internal control over financial reporting as of December 31, 2017 has also been audited by 
Grant Thornton LLP, our independent registered public accounting firm, as stated in their report, which is included below in 
Item 9A(e). 

(c)                     Changes in Internal Controls Over Financial Reporting 

The Company identified control deficiencies related to current and deferred income taxes and inventory costing and 
reserves for the year-ended December 31, 2016, which were assessed as material weaknesses. We developed a remediation 
plan at the time, and designed and implemented certain new internal controls in an effort to remediate the material weaknesses. 
During  the  fourth  quarter  of  fiscal  2017,  we  successfully  completed  the  testing  necessary  to  conclude  that  the  material 
weaknesses had been remediated. 

38 

  
  
  
  
  
  
  
  
  
Except  as  noted  above,  there  has  been  no  change  in  the  Company's  internal  control  over  financial  reporting  as 
of December 31, 2017, that has materially affected, or is reasonably likely to materially affect, the Company's internal control 
over financial reporting.  

(d)                    Inherent Limitations on Effectiveness of Controls 

The design of any system of control is based upon certain assumptions about the likelihood of future events, and there 
can be no assurance that any design will succeed in achieving its stated objectives under all future events, no matter how 
remote, that controls may become inadequate because of changes in conditions, or that the degree of compliance with the 
policies or procedures may not deteriorate. Because of their inherent limitations, systems of control may not prevent or detect 
all misstatements. Accordingly, even effective systems of control can provide only reasonable assurance of achieving their 
control objectives. 

39 

  
  
 
 
(e)           Report of Independent Registered Public Accounting Firm  

Report of Independent Registered Public Accounting Firm 

The Board of Directors and Shareholders 
Harvard Bioscience, Inc.: 

Opinion on internal control over financial reporting 
We  have  audited  the  internal  control  over  financial  reporting  of  Harvard  Bioscience,  Inc.  (a  Delaware  corporation)  and 
subsidiaries (the “Company”) as of December 31, 2017, based on criteria established in the 2013 Internal Control—Integrated 
Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (“COSO”). In our opinion, 
the Company maintained, in all material respects, effective internal control over financial reporting as of December 31, 2017, 
based on criteria established in the 2013 Internal Control—Integrated Framework issued by COSO. 

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) 
(“PCAOB”), the consolidated financial statements of the Company as of and for the year ended December 31, 2017, and our 
report dated March 16, 2018 expressed an unqualified opinion on those financial statements. 

Basis for opinion 
The  Company’s  management  is  responsible  for  maintaining  effective  internal  control  over  financial  reporting  and  for  its 
assessment of the effectiveness of internal control over financial reporting, included in the accompanying Management’s 
Report on Internal Control Over Financial Reporting. Our responsibility is to express an opinion on the Company’s internal 
control over financial reporting based on our audit. We are a public accounting firm registered with the PCAOB and are 
required to be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable 
rules and regulations of the Securities and Exchange Commission and the PCAOB. 

We conducted our audit in accordance with the standards of the PCAOB. Those standards require that we plan and perform 
the audit to obtain reasonable assurance about whether effective internal control over financial reporting was maintained in 
all material respects. Our audit included obtaining an understanding of internal control over financial reporting, assessing the 
risk that a material weakness exists, testing and evaluating the design and operating effectiveness of internal control based 
on the assessed risk, and performing such other procedures as we considered necessary in the circumstances. We believe that 
our audit provides a reasonable basis for our opinion. 

Definition and limitations of internal control over financial reporting 
A company’s internal control over financial reporting is a process designed to provide reasonable assurance regarding the 
reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally 
accepted accounting principles. A company’s internal control over financial reporting includes those policies and procedures 
that  (1)  pertain  to  the  maintenance  of  records  that,  in  reasonable  detail,  accurately  and  fairly  reflect  the  transactions  and 
dispositions of the assets of the company; (2) provide reasonable assurance that transactions are recorded as necessary to 
permit preparation of financial statements in accordance with generally accepted accounting principles, and that receipts and 
expenditures of the company are being made only in accordance with authorizations of management and directors of the 
company; and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or 
disposition of the company’s assets that could have a material effect on the financial statements. 

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, 
projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate 
because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate. 

/s/ GRANT THORNTON, LLP 

Boston, Massachusetts 
March 16, 2018 

40 

  
  
  
  
  
  
  
  
  
  
  
  
  
 
 
Item 9B. 

Other Information.  

None. 

Item 10. 

Directors, Executive Officers and Corporate Governance. 

PART III 

Incorporated by reference to our definitive Proxy Statement to be filed pursuant to Regulation 14A under the Exchange 
Act,  in  connection  with  our  2018  Annual  Meeting  of  Stockholders.  Information  concerning  executive  officers  of  our 
Company is included in Part I of this Annual Report on Form 10-K as Item 1. Business- Executive Officers of the Registrant 
and incorporated herein by reference. 

Item 11. 

Executive Compensation. 

Incorporated by reference to our definitive Proxy Statement to be filed pursuant to Regulation 14A under the Exchange 

Act in connection with our 2018 Annual Meeting of Stockholders. 

Item 12. 

Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters. 

Incorporated by reference to our definitive Proxy Statement to be filed pursuant to Regulation 14A under the Exchange 

Act in connection with our 2018 Annual Meeting of Stockholders. 

Item 13. 

Certain Relationships and Related Transactions, and Director Independence. 

Incorporated by reference to our definitive Proxy Statement to be filed pursuant to Regulation 14A under the Exchange 

Act in connection with our 2018 Annual Meeting of Stockholders. 

Item 14. 

Principal Accounting Fees and Services. 

Incorporated by reference to our definitive Proxy Statement to be filed pursuant to Regulation 14A under the Exchange 

Act in connection with our 2018 Annual Meeting of Stockholders. 

41 

 
  
  
  
 
  
   
  
   
  
   
  
   
  
 
 
Item 15.  Exhibits, Financial Statement Schedules.  

(a)  Documents Filed. The following documents are filed as part of this Annual Report on Form 10-K or incorporated by 
reference as indicated:  

1 

Financial Statements. The consolidated financial statements of Harvard Bioscience, Inc. and its subsidiaries filed
under this Item 15: 

  Page 

Index to Consolidated Financial Statements ....................................................................................................    F-1  

Reports of Independent Registered Public Accounting Firms .........................................................................    F-2  

Consolidated Balance Sheets as of December 31, 2017 and 2016 ..................................................................    F-4 

Consolidated Statements of Operations for the years ended December 31, 2017, 2016 and 2015 ..................    F-5 

Consolidated Statements of Comprehensive Income (Loss) for the years ended December 31, 2017, 2016 
and 2015 ..........................................................................................................................................................  

  F-6 

Consolidated Statements of Stockholders’ Equity for the years ended December 31, 2017, 2016 and 2015 ..    F-7 

Consolidated Statements of Cash Flows for the years ended December 31, 2017, 2016 and 2015 .................    F-8 

Notes to Consolidated Financial Statements ...................................................................................................    F-9 

2 

Exhibits and Exhibit Index. See the Exhibit Index included as the last part of this Annual Report on Form 
10-K, which is incorporated herein by reference. 

42 

  
  
  
  
  
  
  
   
  
  
  
  
  
  
  
  
  
   
  
  
  
  
  
  
  
  
  
   
  
  
  
  
  
  
  
  
  
   
  
  
  
  
  
  
  
  
  
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
 
  
 
  
  
 
INDEX TO CONSOLIDATED FINANCIAL STATEMENTS 

HARVARD BIOSCIENCE, INC. 

   Page 

Reports of Independent Registered Public Accounting Firms .........................................................................................     F-2 

Consolidated Balance Sheets as of December 31, 2017 and 2016 ..................................................................................     F-4 

Consolidated Statements of Operations for the years ended December 31, 2017, 2016 and 2015 ..................................     F-5 

Consolidated Statements of Comprehensive Income (Loss) for the years ended December 31, 2017, 2016 and 2015 ..     F-6 

Consolidated Statements of Stockholders’ Equity for the years ended December 31, 2017, 2016 and 2015 .................     F-7 

Consolidated Statements of Cash Flows for the years ended December 31, 2017, 2016 and 2015 ................................     F-8 

Notes to Consolidated Financial Statements ...................................................................................................................     F-9 

F-1 

  
  
  
  
  
  
  
  
    
  
  
  
  
  
  
  
  
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
 
 
 
Report of Independent Registered Public Accounting Firm 

The Board of Directors and Shareholders 
Harvard Bioscience, Inc.: 

Opinion on the financial statements  
We have audited the accompanying consolidated balance sheet of Harvard Bioscience, Inc. (a Delaware corporation) and 
subsidiaries (the “Company”) as of December 31, 2017, and the related consolidated statements of operations, comprehensive 
loss, stockholders’ equity, and cash flows for the year ended December 31, 2017, and the related notes (collectively referred 
to as the “financial statements”). In our opinion, the financial statements present fairly, in all material respects, the financial 
position of the Company as of December 31, 2017, and the results of its operations and its cash flows for the year ended 
December 31, 2017, in conformity with accounting principles generally accepted in the United States of America. 

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) 
(“PCAOB”), the Company’s internal control over financial reporting as of December 31, 2017, based on criteria established 
in the 2013 Internal Control—Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway 
Commission (“COSO”), and our report dated March 16, 2018, expressed an unqualified opinion. 

Basis for opinion  
These financial statements are the responsibility of the Company’s management. Our responsibility is to express an opinion 
on the Company’s financial statements based on our audit. We are a public accounting firm registered with the PCAOB and 
are  required  to  be  independent  with  respect  to  the  Company  in  accordance  with  the  U.S.  federal  securities  laws  and  the 
applicable rules and regulations of the Securities and Exchange Commission and the PCAOB. 

We conducted our audit in accordance with the standards of the PCAOB. Those standards require that we plan and perform 
the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement, whether 
due to error or fraud. Our audit included performing procedures to assess the risks of material misstatement of the financial 
statements, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included 
examining,  on  a  test  basis,  evidence  supporting  the  amounts  and  disclosures  in  the  financial  statements.  Our  audit  also 
included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the 
overall presentation of the financial statements. We believe that our audit provides a reasonable basis for our opinion. 

/s/ GRANT THORNTON LLP 

We have served as the Company’s auditor since 2017. 

Boston, Massachusetts 
March 16, 2018 

F-2 

  
  
  
  
  
  
  
  
  
  
  
 
 
Report of Independent Registered Public Accounting Firm 

The Board of Directors and Stockholders 
Harvard Bioscience, Inc.: 

We have audited the accompanying consolidated balance sheet of Harvard Bioscience, Inc. and subsidiaries (the Company) 
as of December 31, 2016, and the related consolidated statements of operations, comprehensive (loss) income, stockholders’ 
equity and cash flows for each of the years in the two-year period ended December 31, 2016. These consolidated financial 
statements  are  the  responsibility  of  the  Company’s  management.  Our  responsibility  is  to  express  an  opinion  on  these 
consolidated financial statements based on our audits. 

We  conducted  our  audits  in  accordance  with  the  standards  of  the  Public  Company  Accounting  Oversight  Board  (United 
States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial 
statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts 
and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant 
estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits 
provide a reasonable basis for our opinion. 

In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial 
position of Harvard Bioscience, Inc. and subsidiaries as of December 31, 2016, and the results of their operations and their 
cash flows for each of the years in the two-year period ended December 31, 2016, in conformity with U.S. generally accepted 
accounting principles. 

Cambridge, Massachusetts 
March 16, 2017 

/s/ KPMG LLP 

F-3 

  
  
  
  
  
  
  
  
  
  
 
 
HARVARD BIOSCIENCE, INC. 
CONSOLIDATED BALANCE SHEETS  
(In thousands, except share and per share data)  

   December 31,     December 31, 

2017 

2016 

Assets 
Current assets: 

Cash and cash equivalents ...........................................................................................   $ 
Accounts receivable, net of allowance for doubtful accounts of $454 and $611, 

respectively ..............................................................................................................      
Inventories ...................................................................................................................     
Other receivables and other assets ...............................................................................     
Total current assets ..................................................................................................      

Property, plant and equipment, net ..................................................................................     
Deferred income tax assets ..............................................................................................     
Amortizable intangible assets, net ...................................................................................     
Goodwill ..........................................................................................................................     
Indefinite lived intangible assets .....................................................................................     
Other assets .....................................................................................................................     
Total assets ......................................................................................................................   $ 

Liabilities and Stockholders' Equity 
Current liabilities: 

Current portion, long-term debt ...................................................................................   $ 
Accounts payable ........................................................................................................     
Deferred revenue .........................................................................................................     
Accrued income taxes .................................................................................................     
Accrued expenses ........................................................................................................     
Other liabilities – current .............................................................................................     
Total current liabilities ............................................................................................      

Long-term debt, less current installments ........................................................................     
Deferred income tax liabilities ........................................................................................     
Other long term liabilities ................................................................................................     
Total liabilities.................................................................................................................     

Commitments and contingencies .....................................................................................     

5,733    $

5,596   

16,236      
21,353      
4,213      
47,535      

4,140      
182      
15,960      
39,969      
1,244      
324      
109,354    $

2,765    $
5,404      
633      
387      
4,551      
301      
14,041      

8,983      
3,964      
1,466      
28,454      

15,746   
19,955   
4,175   
45,472   

4,296   
1,157   
17,471   
38,032   
1,209   
128   
107,765   

2,372   
6,196   
500   
223   
4,550   
760   
14,601   

11,374   
6,417   
3,177   
35,569   

Stockholders' equity: 

Preferred stock, par value $0.01 per share, 5,000,000 shares authorized ....................     
Common stock, par value $0.01 per share, 80,000,000 shares authorized; 

42,763,985 and 42,186,827 shares issued and 35,018,478 and 34,441,320 shares 
outstanding, respectively .........................................................................................     
Additional paid-in-capital ............................................................................................     
Accumulated deficit ....................................................................................................     
Accumulated other comprehensive loss ......................................................................     
Treasury stock at cost, 7,745,507 common shares ......................................................     
Total stockholders' equity ........................................................................................      
Total liabilities and stockholders' equity .........................................................................   $ 

-      

-   

419      
218,792      
(116,967)     
(10,676)     
(10,668)     
80,900      
109,354    $

418   
215,134   
(116,030 ) 
(16,658 ) 
(10,668 ) 
72,196   
107,765   

See accompanying notes to consolidated financial statements. 

F-4 

  
  
  
  
  
    
       
    
    
       
    
  
    
       
    
  
    
       
    
    
       
    
    
       
    
  
    
       
    
  
    
       
    
       
    
  
    
       
    
    
       
    
  
  
 
 
HARVARD BIOSCIENCE, INC. 
CONSOLIDATED STATEMENTS OF OPERATIONS 
(In thousands, except per share data) 

Year Ended December 31, 
2016 

2017 

2015 

Revenues ............................................................................................   $
Cost of revenues (exclusive of items shown separately below) .........     
Gross profit .....................................................................................     

101,882    $ 
54,285      
47,597      

104,521    $
56,106      
48,415      

108,664   
59,941   
48,723   

Sales and marketing expenses ............................................................     
General and administrative expenses .................................................     
Research and development expenses ..................................................     
Restructuring (credits) charges ...........................................................     
Amortization of intangible assets .......................................................     
Impairment charges ............................................................................     
Loss on sale of AHN ..........................................................................     
Total operating expenses, net .........................................................     

21,036      
18,575      
5,645      
-      
2,442      
-      
-      
47,698      

20,486      
20,950      
5,392      
(4)     
2,722      
676      
1,190      
51,412      

20,577   
19,832   
6,420   
788   
2,819   
-   
-   
50,436   

Operating loss .....................................................................................     

(101)     

(2,997)     

(1,713 ) 

Other income (expense): 

Foreign exchange ...........................................................................     
Interest expense, net .......................................................................     
Other expense, net ..........................................................................     
Other expense, net ..............................................................................     

Loss before income taxes ...................................................................     
Income tax (benefit) expense..............................................................     
Net loss ...............................................................................................     

(534)     
(713)     
(740)     
(1,987)     

(2,088)     
(1,223)     
(865)     

737      
(639)     
(179)     
(81)     

(3,078)     
1,229      
(4,307)     

210   
(846 ) 
(1,259 ) 
(1,895 ) 

(3,608 ) 
15,431   
(19,039 ) 

Loss per share: 

Basic loss per common share .........................................................   $

(0.02)   $ 

(0.13)   $

(0.57 ) 

Diluted loss per common share ......................................................   $

(0.02)   $ 

(0.13)   $

(0.57 ) 

Weighted average common shares: 

Basic ...............................................................................................     
Diluted ............................................................................................     

34,753      
34,753      

34,212      
34,212      

33,593   
33,593   

See accompanying notes to consolidated financial statements. 

F-5 

  
  
  
  
  
  
  
  
    
    
    
  
    
       
       
    
  
    
       
       
    
  
    
       
       
    
    
       
       
    
  
    
       
       
    
  
    
       
       
    
    
       
       
    
  
    
       
       
    
  
    
       
       
    
    
       
       
    
  
 
 
HARVARD BIOSCIENCE, INC. 
CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS) 
(In thousands) 

Year Ended December 31, 
2016 

2017 

2015 

Net loss ...............................................................................................   $
Other comprehensive income (loss): 
Foreign currency translation adjustments ...........................................     
Derivatives qualifying as hedges, net of tax: 

Loss on derivative instruments designated and qualifying as cash 

flow hedges .................................................................................     

Amounts reclassified from accumulated other comprehensive 

income (loss) to net loss ..............................................................     
Derivatives qualifying as hedges, net of tax ...................................     
Defined benefit pension plans, net of tax: ..........................................     
Amortization of net losses included in net periodic pension costs, 
net of tax expense of $62, $52 and $58 in 2017, 2016 and 2015, 
respectively .................................................................................     

Net gain (loss), net of tax (benefit) expense of ($246), $88 and 

$241 in 2017, 2016 and 2015, respectively .................................     
Defined benefit pension plans, net of tax ...........................................     
Other comprehensive income (loss) ...................................................     
Comprehensive income (loss) ............................................................   $

(865)   $ 

(4,307)   $

(19,039 ) 

4,445      

(4,606)     

(4,936 ) 

(24)     

61      
37      

(29)     

39      
10      

(85 ) 

93   
8   

300      

252      

248   

1,200      
1,500      
5,982      
5,117    $ 

(430)     
(178)     
(4,774)     
(9,081)   $

1,029   
1,277   
(3,651 ) 
(22,690 ) 

See accompanying notes to consolidated financial statements. 

F-6 

  
  
  
  
  
  
  
  
    
    
    
  
    
    
    
    
       
       
    
    
       
       
    
       
       
    
  
 
 
HARVARD BIOSCIENCE, INC. 
CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY 
(In thousands) 

   Number of       
   Shares 
Issued 

    Additional      

     Accumulated        
Other 

Total 

    Common     Paid-in      Accumulated    Comprehensive    Treasury    Stockholders’   
     Stock 

    Income (Loss)      Stock 

     Capital       Deficit 

     Equity 

Balance at December 31, 2014 ..........      
Stock option exercises ...................      
Stock purchase plan ......................      
Vesting of restricted stock units ....      
Shares withheld for taxes ..............      
Stock compensation expense .........      
Net income ....................................      
Other comprehensive loss .............      
Balance at December 31, 2015 ..........      
Stock option exercises ...................      
Stock purchase plan ......................      
Vesting of restricted stock units ....      
Shares withheld for taxes ..............      
Stock compensation expense .........      
Net loss .........................................      
Other comprehensive loss .............      
Balance at December 31, 2016 ..........      

Share based payment change in 

accounting principle ..................      
Stock option exercises ...................      
Stock purchase plan, net ................      
Vesting of restricted stock units ....      
Shares withheld for taxes ..............      
Stock compensation expense .........      
Net loss .........................................      
Other comprehensive income ........      
Balance at December 31, 2017 ..........      

40,309    $ 
1,772      
59      
237      
(652)     
-      
-      
-      
41,725      
375      
81      
302      
(296)     
-      
-      
-      
42,187      

-      
143      
76      
489      
(131)     
-      
-      
-      
42,764    $ 

397     $  206,656    $ 
2,605      
25       
208      
-       
-      
-       
(767)    
(6 )    
2,755      
-       
-      
-       
-      
-       
416        211,457      
167      
196      
-      
(183)    
3,497      
-      
-      
418        215,134      

4       
-       
-       
(2 )    
-       
-       
-       

-       
2       
-       
-       
(1 )    
-       
-       
-       

72      
188      
140      
-      
(242)    
3,500      
-      
-      
419     $  218,792    $ 

(92,684)  $ 
-      
-      
-      
-      
-      
(19,039)    
-      
(111,723)    
-      
-      
-      
-      
-      
(4,307)    
-      
(116,030)    

(72)    
-      
-      
-      
-      
-      
(865)    
-      
(116,967)  $ 

-      
-      
-      
-      
-      
-      
(3,651)    

(8,233)  $  (10,668 )  $ 
-       
-       
-       
-       
-       
-       
-       
(11,884)     (10,668 )    
-       
-       
-       
-       
-       
-       
-       
(16,658)     (10,668 )    

-      
-      
-      
-      
-      
-      
(4,774)    

-      
-      
-      
-      
-      
-      
-      
5,982      

-       
-       
-       
-       
-       
-       
-       
-       
(10,676)  $  (10,668 )  $ 

95,468  
2,630  
208  
-  
(773)
2,755  
(19,039)
(3,651)
77,598  
171  
196  
-  
(185)
3,497  
(4,307)
(4,774)
72,196  

-  
190  
140  
-  
(243)
3,500  
(865)
5,982  
80,900  

See accompanying notes to consolidated financial statements. 

F-7 

 
  
  
  
      
  
      
  
      
  
  
      
  
  
  
  
  
    
      
  
    
  
  
  
  
  
 
 
 
HARVARD BIOSCIENCE, INC. 
CONSOLIDATED STATEMENTS OF CASH FLOWS 
(In thousands) 

Cash flows from operating activities: 

Net loss ...........................................................................................   $
Adjustments to reconcile net loss to net cash provided by 

operating activities: 
Stock compensation expense ......................................................     
Depreciation ...............................................................................     
Impairment charges ....................................................................     
Loss on sale of AHN ..................................................................     
(Gain) loss on sale of assets, net .................................................     
Non-cash restructuring (credit) ...................................................     
Amortization of catalog costs .....................................................     
(Recovery of) provision for allowance for doubtful accounts ....     
Amortization of intangible assets ...............................................     
Amortization of deferred financing costs ...................................     
Deferred income taxes ................................................................     
Changes in operating assets and liabilities: 

Decrease (increase) in accounts receivable ............................     
(Increase) decrease in inventories...........................................     
(Increase) decrease in other receivables and other assets .......     
(Decrease) increase in trade accounts payable .......................     
Decrease (increase) in accrued income taxes .........................     
(Decrease) increase in accrued expenses ................................     
Increase (decrease) in deferred revenue .................................     
(Decrease) increase in other liabilities ....................................     
Net cash provided by operating activities ...........................     

Cash flows (used in) provided by investing activities: 

Additions to property, plant and equipment ...................................     
Additions to catalog costs ...............................................................     
Proceeds from disposition ..............................................................     
Proceeds from sales of property, plant and equipment ...................     
Acquisitions, net of cash acquired ..................................................     
Net cash used in investing activities ...........................................     

Cash flows provided by (used in) financing activities: 

Proceeds from issuance of debt ......................................................     
Repayments of debt ........................................................................     
Payments of debt issuance costs .....................................................     
Net proceeds from issuance of common stock ...............................     
Net cash used in financing activities ..........................................     

Effect of exchange rate changes on cash ............................................     
Increase (decrease) in cash and cash equivalents ...............................     
Cash and cash equivalents at the beginning of period ........................     
Cash and cash equivalents at the end of period ..................................   $

Year Ended December 31, 
2016 

2017 

2015 

(865)   $ 

(4,307)   $

(19,039 ) 

3,500      
1,317      
-      
93      
(12)     
-      
42      
(109)     
2,442      
44      
(1,584)     

196      
(548)     
(102)     
(918)     
212      
(736)     
95      
(2,010)     
1,057      

(890)     
(39)     
-      
12      
-      
(917)     

2,750      
(4,702)     
-      
160      
(1,792)     

1,789      
137      
5,596      
5,733    $ 

3,497      
1,532      
676      
1,190      
-      
(27)     
20      
309      
2,722      
91      
(279)     

566      
1,248      
(658)     
(2,413)     
(195)     
871      
(187)     
727      
5,383      

(1,445)     
(34)     
1,417      
-      
-      
(62)     

4,000      
(9,050)     
-      
182      
(4,868)     

(1,601)     
(1,148)     
6,744      
5,596    $

2,755   
1,745   
-   
-   
25   
(85 ) 
9   
(7 ) 
2,819   
86   
15,116   

(1,340 ) 
(1,223 ) 
755   
2,577   
(311 ) 
(1,511 ) 
120   
(1,786 ) 
705   

(2,960 ) 
(18 ) 
-   
6   
(4,545 ) 
(7,517 ) 

5,800   
(8,350 ) 
(32 ) 
2,042   
(540 ) 

(38 ) 
(7,390 ) 
14,134   
6,744   

Supplemental disclosures of cash flow information: 

Cash paid for interest ......................................................................   $
Cash paid for income taxes, net of refunds ....................................   $

686    $ 
(13)   $ 

620    $
928    $

854   
963   

See accompanying notes to consolidated financial statements. 

F-8 

  
  
  
  
  
  
  
    
       
       
    
    
       
       
    
    
       
       
    
  
    
       
       
    
    
       
       
    
  
    
       
       
    
    
       
       
    
  
    
       
       
    
  
    
       
       
    
    
       
       
    
  
  
HARVARD BIOSCIENCE, INC.  
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS 

1. 

Organization 

Harvard Bioscience, Inc. ( “Harvard Bioscience” or “the Company”) is a global developer, manufacturer and marketer 
of a broad range of scientific instruments and systems used to advance life science for basic research, drug discovery, clinical 
and environmental testing. The Company’s products are sold to thousands of researchers in over 100 countries through its 
global sales organization, websites, catalogs, and through distributors including Thermo Fisher Scientific Inc., VWR and 
other  specialized  distributors.  The  Company  has  sales  and  manufacturing  operations  in  the  United  States,  the  United 
Kingdom, Germany, Sweden, Spain, France, Canada and China. 

2. 

Summary of Significant Accounting Policies 

(a)  

Principles of Consolidation 

The  consolidated  financial  statements  include  the  accounts  of  Harvard  Bioscience, Inc.  and  its  wholly-owned 

subsidiaries. All intercompany balances and transactions have been eliminated in consolidation. 

(b) 

Use of Estimates 

The  preparation  of  financial  statements  in  conformity  with  accounting  principles  generally  accepted  in  the  United 
States  requires  the  use  of  management  estimates.  Such  estimates  include  the  determination  and  establishment  of  certain 
accruals and provisions, including those for inventory excess and obsolescence, income tax and reserves for bad debts. In 
addition, certain estimates are required in order to determine the value of assets and liabilities associated with acquisitions, 
as  well  as  the  Company’s  defined  benefit  pension  obligations.  Estimates  are  also  required  to  evaluate  the  value  and 
recoverability of existing long-lived and intangible assets, including goodwill. On an ongoing basis, the Company reviews 
its estimates based upon currently available information. Actual results could differ materially from those estimates. 

(c) 

Cash and Cash Equivalents 

For purposes of the consolidated balance sheets and statements of cash flows, the Company considers all highly liquid 

instruments with original maturities of three months or less to be cash equivalents. 

For the purposes of reporting consolidated cash flows, cash and cash equivalents include cash on hand and amounts 
due from banks. The Company maintains a portion of its cash in bank deposit accounts which, at times, may exceed federally 
insured limits. The Company has not experienced any losses in such accounts. The Company believes it is not exposed to 
any significant risk with respect to these accounts. 

(d) 

Allowance for Doubtful Accounts 

Allowance for doubtful accounts is based on the Company’s assessment of collectability of customer accounts. The 
Company  regularly  reviews  the  allowance  by  considering  factors  such  as  historical  experience,  credit  quality,  age  of  the 
accounts receivable balances and other factors that may affect a customer’s ability to pay. 

(e) 

Inventories 

The  Company  values  its  inventories  at  the  lower  of  the  actual  cost  to  purchase  (first-in,  first-out  method)  and/or 
manufacture  the  inventories  or  the  current  estimated  market  value  of  the  inventories.  The  Company  regularly  reviews 
inventory  quantities  on  hand  and  records  a  provision  to  write  down  excess  and  obsolete  inventories  to  its  estimated  net 
realizable value if less than cost, based primarily on historical inventory usage and estimated forecast of product demand. 

(f) 

Property, Plant and Equipment 

Property,  plant  and  equipment  are  stated at cost  and  depreciated  using  the  straight-line method over  the  estimated 

useful lives of the assets as follows: 

  40 years 
Buildings .....................................................................................................................................   
Machinery and equipment ...........................................................................................................  3 -  10 years 
Computer equipment and software ..............................................................................................  3 -  7 years 
Furniture and fixtures ..................................................................................................................  5 -  10 years 
Automobiles ................................................................................................................................  3 -  6 years 

F-9 

 
 
  
  
  
  
  
Property and equipment held under capital leases and leasehold improvements are amortized using the straight line 

method over the shorter of the lease term or estimated useful life of the asset. 

(g) 

Catalog Costs 

Significant  costs  of  product  catalog  design,  development  and  production  are  capitalized  and  amortized  over  the 

expected useful life of the catalog (usually one to three years). 

(h)  

Income Taxes 

Income taxes are accounted for under the asset and liability method. Deferred tax assets and liabilities are recognized 
for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets 
and liabilities and their respective tax bases. Deferred tax assets and liabilities are measured using enacted tax rates expected 
to be applied to taxable income in the years in which those temporary differences are expected to be recovered or settled. The 
effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the 
enactment date. 

The Company recognizes the effect of income tax positions only if those positions are more likely than not of being 
sustained. Recognized income tax positions are measured at the largest amount that is more than 50% likely of being realized. 
Changes in recognition are reflected in the period in which the judgement occurs. 

(i) 

Foreign Currency Translation 

The  functional  currency  of  the  Company’s  foreign  subsidiaries  is  generally  their  local  currency.  All  assets  and 
liabilities of its foreign subsidiaries are translated at exchange rates in effect at period-end. Income and expenses are translated 
at  rates  which  approximate  those  in  effect  on  the  transaction  dates.  The  resulting  translation  adjustment  is  recorded  as  a 
separate component of stockholders’ equity in accumulated other comprehensive (loss) income (AOCI) in the consolidated 
balance sheets. Gains and losses resulting from foreign currency transactions are included in net (loss) income. 

(j) 

Earnings per Share 

Basic earnings per share is computed by dividing net income by the weighted average number of shares of common 
stock outstanding during the periods presented. The computation of diluted earnings per share is similar to the computation 
of basic earnings per share, except that the denominator is increased for the assumed exercise of dilutive options and other 
potentially dilutive securities using the treasury stock method unless the effect is antidilutive. 

(k) 

Comprehensive Income (Loss) 

The  Company  follows  the  provisions  of  Financial  Accounting  Standards  Board  (FASB)  Accounting  Standards 
Codification (ASC) 220, “Comprehensive Income”. FASB ASC 220 requires companies to report all changes in equity during 
a period, resulting from net (loss) income and transactions from non-owner sources, in a financial statement in the period in 
which they are recognized. The Company has chosen to disclose comprehensive income (loss), which encompasses net loss, 
foreign currency translation adjustments, gains and losses on derivatives, the underfunded status of its pension plans, and 
pension minimum additional liability adjustments, net of tax, in the consolidated statements of comprehensive income (loss). 

(l) 

Revenue Recognition 

The Company follows the provisions of FASB ASC 605, “Revenue Recognition”. The Company recognizes product 
revenues when persuasive evidence of a sales arrangement exists, the price to the buyer is fixed or determinable, delivery has 
occurred, and collectability of the sales price is reasonably assured. Sales of some of its products include provisions to provide 
additional services such as installation and training. Revenues on these products are recognized when the additional services 
have been performed. Service agreements on its equipment are typically sold separately from the sale of the equipment. Cash 
received prior to rendering of the service on these contracts is recorded as deferred revenue and the revenues are recognized 
ratably over the life of the agreement, typically one year, in accordance with the provisions of FASB ASC 605-20, “Revenue 
Recognition—Services”. 

The Company accounts for shipping and handling fees and costs in accordance with the provisions of FASB ASC 605-
45-45,  “Revenue  Recognition—Principal  Agent  Considerations”,  which  requires  all  amounts  charged  to  customers  for 
shipping and handling to be classified as revenues. The costs incurred related to shipping and handling is classified as cost of 
product revenues. Warranties and product returns are estimated and accrued for at the time sales are recorded. The Company 
has no obligations to customers after the date products are shipped or installed, if applicable, other than pursuant to warranty 

F-10 

obligations and service or maintenance contracts. The Company provides for the estimated amount of future returns upon 
shipment of products or installation, if applicable, based on historical experience. 

Sales  taxes,  value  added  taxes,  and  certain  excise  taxes  collected  from  customers  and  remitted  to  governmental 

authorities are accounted for on a net basis, and are therefore excluded from revenues. 

(m) 

Valuation of Identifiable Intangible Assets Acquired in Business Combinations 

The determination of the fair value of intangible assets, which represents a significant portion of the purchase price in 
the Company’s acquisitions, requires the use of significant judgment with regard to (i) the fair value; and (ii) whether such 
intangibles are amortizable or not amortizable and, if the former, the period and the method by which the intangibles asset 
will  be  amortized.  The  Company  estimates  the  fair  value  of  acquisition-related  intangible  assets  principally  based  on 
projections  of  cash  flows  that  will  arise  from  identifiable  assets  of  acquired  businesses.  The  projected  cash  flows  are 
discounted  to  determine  the  present  value  of  the  assets  at  the  dates  of  acquisitions.  At  December  31,  2017,  amortizable 
intangible assets include existing technology, trade names, distribution agreements, customer relationships and patents. These 
amortizable intangible assets are amortized on a straight-line basis over 7 to 15 years, 10 to 15 years, 4 to 5 years, 5 to 15 
years and 5 to 15 years, respectively. 

(n) 

Goodwill and Other Intangible Assets 

Goodwill and unamortizable intangible assets acquired in a business combination and determined to have an indefinite 
useful  life  are  not  amortized,  but  instead  are  tested  for  impairment  annually  or  more  frequently  if  events  or  changes  in 
circumstances indicate that the asset might be impaired, in accordance with the provisions of FASB ASC 350, “Intangibles—
Goodwill and Other”. 

For the purpose of its goodwill analysis, the Company has one reporting unit. The Company conducted its annual 
impairment analysis in the fourth quarter of fiscal year 2017. The goodwill impairment test is a two-step process. The first 
step of the impairment analysis compares the Company’s fair value to its carrying value to determine if there is any indication 
of impairment. Step two of the analysis compares the implied fair value of goodwill to its carrying amount in a manner similar 
to a purchase price allocation for business combination. If the carrying amount of goodwill exceeds its implied fair value, an 
impairment loss is recognized equal to that excess. For indefinite-lived intangible assets if the carrying amount exceeds the 
fair value of the asset, the Company would write down the indefinite-lived intangible asset to fair value. 

At  December  31,  2017,  the  fair  value  of  the  Company  significantly  exceeded  the  carrying  value.  The  Company 

concluded that none of its goodwill was impaired. 

The  Company  evaluates  indefinite-lived  intangible  assets  for  impairment  annually  and  when  events  occur  or 
circumstances change that may reduce the fair value of the asset below its carrying amount.  Events or circumstances that 
might  require  an  interim  evaluation  include  unexpected  adverse  business  conditions,  economic  factors,  unanticipated 
technological changes or competitive activities, loss of key personnel and acts by governments and courts. At December 31, 
2017, the Company concluded that none of its indefinite-lived intangible assets were impaired. 

(o) 

Impairment of Long-Lived Assets 

The  Company  assesses  recoverability  of  its  long-lived  assets  that  are  held  for  use,  such  as  property,  plant  and 
equipment and amortizable intangible assets in accordance with FASB ASC 360, “Property, Plant and Equipment” when 
events or  changes  in  circumstances  indicate  that  the  carrying  amount  of an  asset  or  asset  group  may  not be  recoverable. 
Recoverability of assets or an asset group to be held and used is measured by a comparison of the carrying amount of an asset 
or asset group to estimated undiscounted future cash flows expected to be generated by the asset or the asset group. Cash 
flow  projections  are  based  on  trends  of  historical  performance  and  management’s  estimate  of  future  performance.  If  the 
carrying amount of the asset or asset group exceeds the estimated future cash flows, an impairment charge is recognized by 
the amount by which the carrying amount of the asset or asset group exceeds its estimated fair value. At December 31, 2017, 
the Company concluded that none of its long-lived assets were impaired. 

(p) 

Derivatives 

The Company uses interest-rate-related derivative instruments to manage its exposure related to changes in interest 
rates on its variable-rate debt instruments. The Company does not enter into derivative instruments for any purpose other than 
cash flow hedging. The Company does not speculate using derivative instruments. The Company recognizes all derivative 
instruments as either assets or liabilities in the balance sheet at their respective fair values. For derivatives designated in 
hedging  relationships,  changes  in  the  fair  value  are  either  offset  through  earnings  against  the  change  in  fair  value  of  the 

F-11 

hedged item attributable to the risk being hedged or recognized in AOCI, to the extent the derivative is effective at offsetting 
the changes in cash flows being hedged until the hedged item affects earnings. 

The Company only enters into derivative contracts that it intends to designate as a hedge of a forecasted transaction or 
the variability of cash flows to be received or paid related to a recognized asset or liability (cash flow hedge). For all hedging 
relationships, the Company formally documents the hedging relationship and its risk-management objective and strategy for 
undertaking the hedge, the hedging instrument, the hedged transaction, the nature of the risk being hedged, how the hedging 
instrument’s effectiveness in offsetting the hedged risk will be assessed prospectively and retrospectively, and a description 
of the method used to measure ineffectiveness.  The Company also formally assesses, both at the inception of the hedging 
relationship and on an ongoing basis, whether the derivatives that are used in hedging relationships are highly effective in 
offsetting changes in cash flows of hedged transactions. For derivative instruments that are designated and qualify as part of 
a cash flow hedging relationship, the effective portion of the gain or loss on the derivative is reported as a component of other 
comprehensive  income  and  reclassified  into  earnings  in  the  same  period  or  periods  during  which  the  hedged  transaction 
affects earnings. Gains and losses on the derivative representing either hedge ineffectiveness or hedge components excluded 
from the assessment of effectiveness are recognized in current earnings. 

The Company discontinues hedge accounting prospectively when it determines that the derivative is no longer effective 
in offsetting cash flows attributable to the hedged risk, the derivative expires or is sold, terminated, or exercised, the cash 
flow  hedge  is  de-designated because  a  forecasted  transaction  is  not  probable  of  occurring,  or  management  determines  to 
remove the designation of the cash flow hedge. 

In  all  situations  in  which  hedge  accounting  is  discontinued  and  the  derivative  remains  outstanding,  the  Company 
continues to carry the derivative at its fair value on the balance sheet and recognizes any subsequent changes in its fair value 
in earnings. When it is probable that a forecasted transaction will not occur, the Company discontinues hedge accounting and 
recognizes immediately in earnings gains and losses that were accumulated in other comprehensive income related to the 
hedging relationship. 

(q) 

Fair Value of Financial Instruments 

The carrying values of the Company’s cash and cash equivalents, trade accounts receivable and trade accounts payable 
and short-term debt approximate their fair values because of the short maturities of those instruments. The fair value of the 
Company’s long-term debt approximates its carrying value and is based on the amount of future cash flows associated with 
the debt discounted using current borrowing rates for similar debt instruments of comparable maturity. 

Financial reporting standards define a fair value hierarchy that consists of three levels: 

 

 

 

Level  1  includes  instruments  for  which  quoted  prices  in  active  markets  for  identical  assets  or  liabilities
accessible to the Company at the measurement date. 

Level 2 includes instruments for which the valuations are based on quoted prices for similar assets or liabilities, 
quoted  prices  in  markets  that  are  not  active,  or  other  inputs  that  are  observable  or  can  be  corroborated  by
observable data for substantially the full term of the assets or liabilities. 

Level  3  includes  valuations  based  on  inputs  that  are  unobservable  and  significant  to  the  overall  fair  value
measurement. 

(r) 

Stock-based Compensation 

The  Company  accounts  for  stock-based  payment  awards  in  accordance  with  the  provisions  of  FASB  ASC  718, 
“Compensation—Stock Compensation”, which requires it to recognize compensation expense for all stock-based payment 
awards made to employees and directors including stock options, restricted stock units, restricted stock units with a market 
condition  and  employee  stock  purchases  (“employee  stock  purchases”)  related  to  its  Employee  Stock  Purchase  Plan  (as 
amended, the ESPP). The Company issues new shares upon stock option exercises, upon vesting of restricted stock units and 
restricted stock units with a market condition, and under the Company’s ESPP. 

F-12 

  
  
  
 
 
Stock-based compensation expense recognized is based on the value of the portion of stock-based payment awards 
that is ultimately expected to vest. The value of the award is recognized as expense as it vests over the requisite service 
periods  in  its consolidated  statements  of  operations.  The Company  values  stock-based  payment  awards,  except restricted 
stock units at grant date using the Black-Scholes option-pricing model (Black-Scholes model). The Company values restricted 
stock units with a market condition using a Monte-Carlo valuation simulation. The determination of fair value of stock-based 
payment awards on the date of grant using an option-pricing model or Monte-Carlo valuation simulation is affected by its 
stock price as well as assumptions regarding certain variables. These variables include, but are not limited to its expected 
stock price volatility over the term of the awards and actual and projected stock option exercise behaviors. 

The fair value of restricted stock units are based on the market price of the Company’s stock on the date of grant and 
are  recorded  as  compensation  expense  ratably  over  the  applicable  service  period,  which  ranges  from  one  to  four  years. 
Unvested restricted stock units are forfeited in the event of termination of employment with the Company. 

Stock-based compensation expense recognized under FASB ASC 718 for the years ended December 31, 2017, 2016 
and 2015 consisted of stock-based compensation expense related to stock options, the employee stock purchase plan, and the 
restricted stock units and was recorded as a component of cost of product revenues, sales and marketing expenses, general 
and administrative expenses, research and development expenses and discontinued operations. Refer to footnote 19 for further 
details. 

(s) 

Recently Issued Accounting Pronouncements 

In  February  2016,  the  FASB  issued  ASU  2016-02,  Leases,  which  is  intended  to  improve  financial  reporting  about 
leasing transactions. The update requires a lessee to record on the balance sheet the assets and liabilities for the rights and 
obligations  created  by  lease  terms  of  more  than  12 months.  The  update  is  effective  for  fiscal  years  beginning  after 
December 15, 2018. The Company has commenced the process of evaluating the requirements of the standard as well as 
collecting information on all its leases. The Company has not yet concluded on the impact of the adoption on its consolidated 
financial position, results of operations and cash flows, however, assets and liabilities will increase upon adoption for right-
of-use assets and lease liabilities.  The Company’s future commitments under lease obligations are summarized in Note 14. 

In June 2016, the FASB issued ASU 2016-13, Financial Instruments – Credit Losses (Topic 326), Measurement of 
credit losses on Financial Instruments. The update amends the FASB’s guidance on the impairment of financial instruments. 
The ASU adds to U.S. GAAP an impairment model (known as the current expected credit loss (CECL) model) that is based 
on expected losses rather than incurred losses. Under the new guidance, an entity recognizes as an allowance its estimate of 
expected credit losses, which the FASB believes will result in more timely recognition of such losses. The ASU is effective 
for fiscal years beginning after December 15, 2019, including  interim periods within those fiscal years. The Company is 
evaluating the impact of ASU 2016-13 on its consolidated financial statements. 

In  August  2017,  the  FASB  issued  ASU  2017-12, Derivatives  and  Hedging  (Topic  815) which  amends  the  hedge 
accounting  recognition  and presentation  requirements  in ASC  815.  The  Board’s objectives  in  issuing  the  ASU  are  to  (1) 
improve the transparency and understandability of information conveyed to financial statement users about an entity’s risk 
management activities by better aligning the entity’s financial reporting for hedging relationships with those risk management 
activities  and  (2)  reduce  the  complexity  of  and  simplify  the  application  of  hedge  accounting  by  preparers.  The  ASU  is 
effective  for  annual  reporting  periods,  including  interim  periods  within  those  annual  reporting  periods,  beginning  after 
December 15, 2018. Early adoption is permitted, including adoption in any interim period. The Company is evaluating the 
requirements of this guidance and has not yet determined the impact of the adoption on its consolidated financial position, 
results of operations and cash flows. 

Recently Adopted Accounting Pronouncements 

Adopted in 2017 

In March 2016, the FASB issued ASU 2016-09, Compensation – Stock Compensation (Topic 718): Improvements to 
Employee  Share-Based  Payment  Accounting,  which  simplifies  the  accounting  for  share-based  payment  transactions, 
including  the  income  tax  consequences,  classification  of  awards  as  either  equity  or  liabilities  and  classification  on  the 
statement of cash flows. 

The standard requires an entity to recognize all excess tax benefits and tax deficiencies as income tax benefit or expense 
in the income statement as discrete items in the reporting period in which they occur, and such tax benefits and tax deficiencies 
are not included in the estimate of an entity’s annual effective tax rate, applied on a prospective basis. Further, the standard 
eliminates the requirement to defer the recognition of excess tax benefits until the benefit is realized through a reduction to 

F-13 

  
  
   
  
  
  
  
  
  
  
taxes payable. All excess tax benefits previously unrecognized, along with any valuation allowance, should be recognized on 
a modified retrospective basis as a cumulative adjustment to retained earnings as of the date of adoption. Under ASU 2016-
09, an entity that applies the treasury stock method in calculating diluted earnings per share is required to exclude excess tax 
benefits  and  deficiencies  from  the  calculation  of  assumed  proceeds  since  such  amounts  are  recognized  in  the  income 
statement. Excess tax benefits should also be classified as operating activities in the same manner as other cash flows related 
to income taxes on the statement of cash flows, as such excess tax benefits no longer represent financing activities since they 
are recognized in the income statement, and should be applied prospectively or retrospectively to all periods presented. 

The Company adopted ASU 2016-09 as of January 1, 2017. The Company recorded a cumulative increase in retained 
earnings of $0.5 million at the beginning of the first quarter of 2017 with a corresponding increase in deferred tax assets 
related to the prior years’ unrecognized excess tax benefits. An equal amount of valuation allowance was also recorded against 
these deferred tax assets with a corresponding decrease to retained earnings resulting in no net impact to retained earnings 
and deferred tax assets. In addition, tax deficiencies related to vested restricted stock units and canceled stock options during 
the year ended December 31, 2017 have been recognized in the current period’s income statement. 

ASU 2016-09 also allows an entity to elect as an accounting policy either to continue to estimate the total number of 
awards for which the requisite service period will not be rendered or to account for forfeitures for service based awards as 
they occur. An entity that elects to account for forfeitures as they occur should apply the accounting change on a modified 
retrospective basis as a cumulative effect adjustment to retained earnings as of the date of adoption. The Company elected as 
an accounting policy to account for forfeitures for service based awards as they occur, and as a result, the Company recorded 
a cumulative effect adjustment of $0.1 million to reduce retained earnings with a corresponding increase in additional paid 
in capital related to the prior years’ stock-based compensation expense as required under the modified retrospective approach. 
The tax effect of this adjustment, which included the impact of a valuation allowance was immaterial. 

Adopted in 2018 

In May 2014, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) 2014-
09, Revenue from Contracts with Customers, a new accounting standard that provides for a comprehensive model to use in 
the accounting for revenue arising from contracts with customers that will replace most existing revenue recognition guidance 
within generally accepted accounting principles in the United States. Under this standard, revenue will be recognized to depict 
the transfer of promised goods or services to customers in an amount that reflects the consideration to which the Company 
expects to be entitled in exchange for those goods or services. 

The Company has completed the process of evaluating the impact of the new standard on its consolidated financial 
position, results of operations and cash flows. The Company adopted this standard as of January 1, 2018 using the modified 
retrospective approach. As part of the implementation of the standard, the Company identified its significant revenue streams, 
which currently consist primarily of product revenue transactions, and to a lesser extent, extended warranty transactions on 
certain product sales, and revenues from government contracts. The timing of recognizing revenues for these revenue streams 
is  not  expected  to  materially  change.  Additionally,  no  material  changes  to  business  processes,  systems  and  controls  are 
expected. The Company is drafting enhanced revenue disclosures which will be presented prospectively starting in the first 
quarter of 2018. 

In  May  2017,  the  FASB  issued  ASU  2017-09, Stock  compensation  (Topic  718):  Scope  of  modification 
accounting which amends the scope of modification accounting for share-based payment arrangements. The ASU provides 
guidance on the types of changes to the terms or conditions of share-based payment awards to which an entity would be 
required to apply modification accounting under ASC 718. Specifically, an entity would not apply modification accounting 
if  the  fair  value,  vesting  conditions,  and  classification  of  the  awards  are  the  same  immediately  before  and  after  the 
modification. The ASU  is  effective  for annual  reporting  periods,  including  interim  periods within  those  annual  reporting 
periods, beginning after December 15, 2017. The Company adopted this guidance on January 1, 2018, and the new standard 
did not have a material impact on its consolidated financial position, results of operations and cash flows.. 

3. 

Concentrations 

No customer accounted for more than 10% of revenues for the years ended December 31, 2017, 2016 and 2015. At 

December 31, 2017 and 2016, no customer accounted for more than 10% of net accounts receivable. 

F-14 

 
  
  
  
  
  
  
 
  
 
 
4. 

Accumulated Other Comprehensive Loss 

Changes in each component of accumulated other comprehensive loss, net of tax are as follows: 

(in thousands) 

  Foreign currency    Derivatives 
   qualifying as 

translation 
adjustments 

hedges 

   Defined benefit    
   pension plans    

Total 

Balance at December 31, 2015 ...........................   $ 

(9,594 )   $ 

(10)   $ 

(2,280)   $

(11,884 ) 

Other comprehensive (loss) income before 

reclassifications.................................................     
Amounts reclassified from AOCI .........................     

(4,606 )     
-       

(29)     
39      

(430)     
252      

(5,065 ) 
291   

Net other comprehensive (loss) income ...............     

(4,606 )     

10      

(178)     

(4,774 ) 

Balance at December 31, 2016 ...........................     

(14,200 )   $ 

-      

(2,458)     

(16,658 ) 

Other comprehensive (loss) income before 

reclassifications.................................................     
Amounts reclassified from AOCI .........................     

4,445       
-       

(24)     
61      

1,200      
300      

5,621   
361   

Other comprehensive (loss) income .....................     

4,445       

37      

1,500      

5,982   

Balance at December 31, 2017 ...........................   $ 

(9,755 )   $ 

37    $ 

(958)   $

(10,676 ) 

The amounts reclassified out of accumulated other comprehensive (loss) income are as follows: 

(in thousands) 

  Affected line item in the   
  Statements of Operations   

Amounts Reclassified From AOCI 
Derivatives qualifying as hedges 

Realized loss on derivatives qualifying as 

hedges ......................................................  

 $
Income tax ..................................................  Income tax (benefit) expense    

Interest expense 

Defined benefit pension plans 

Amortization of net losses included in net 

periodic pension costs ..............................  

General and administrative 
expenses 

Income tax ..................................................  Income tax (benefit) expense    

Year Ended December 31, 
2016 

2017 

2015 

61   $
-     
61     

362     
(62)   
300     

39   $ 
-     
39     

304     
(52)    
252     

93  
-  
93  

306  
(58) 
248  

341  

Total reclassifications .............................  

 $

361   $

291   $ 

5. 

Inventories 

Inventories consist of the following: 

Finished goods.................................................................................................................   $ 
Work in process ...............................................................................................................     
Raw materials ..................................................................................................................     
Total ............................................................................................................................   $ 

10,284    $ 
1,042      
10,027      
21,353    $ 

9,340   
823   
9,792   
19,955   

   December 31,     December 31, 

2017 

2016 

(in thousands) 

F-15 

 
  
  
  
    
    
  
  
 
  
  
  
    
  
     
    
  
    
        
       
       
    
  
    
        
       
       
    
  
    
        
       
       
    
  
    
        
       
       
    
  
    
        
       
       
    
  
    
        
       
       
    
  
  
  
 
 
  
   
   
   
   
   
   
      
      
   
   
   
      
      
   
  
   
   
   
   
      
      
   
   
  
   
   
  
   
   
      
      
   
   
  
 
  
  
  
  
  
  
  
  
 
6. 

Property, Plant and Equipment 

Property, plant and equipment consist of the following: 

   December 31,     December 31, 

2017 

2016 

Land, buildings and leasehold improvements .................................................................   $ 
Machinery and equipment ...............................................................................................     
Computer equipment and software ..................................................................................     
Furniture and fixtures ......................................................................................................     
Automobiles ....................................................................................................................     

Less: accumulated depreciation .......................................................................................     
Property, plant and equipment, net ..................................................................................   $ 

(in thousands) 
2,220    $ 
7,758      
9,149      
1,243      
120      
20,490      
(16,350)     
4,140    $ 

2,095   
7,224   
8,115   
1,274   
196   
18,904   
(14,608 ) 
4,296   

7. 

Acquisitions 

As further discussed in Note 25 (Subsequent Events) on January 31, 2018, the Company completed the acquisition of 

Data Sciences International, Inc. 

HEKA Elektronik 

On January 8, 2015, the Company, through its wholly-owned Ealing Scientific Limited and Multi-Channel Systems 
MCS  GmbH  (MCS)  subsidiaries,  acquired  all  of  the  issued  and  outstanding  shares  of  HEKA  Elektronik  (HEKA)  for 
approximately  $5.9  million,  or  $4.5  million,  net  of  cash  acquired.  Included  in  the  acquisition  of  HEKA  were:  HEKA 
Electronik Dr. Schulze GmbH, based in Lambrecht, Germany (HEKA Germany); HEKA Electronics Incorporated, based in 
Chester, Nova Scotia, Canada (HEKA Canada); and HEKA Instruments Incorporated, based in Bellmore, New York. The 
Company funded the acquisition from its existing cash balances. 

HEKA is a developer, manufacturer and marketer of sophisticated electrophysiology instrumentation and software for 
biomedical and industrial research applications. This acquisition is complementary to the electrophysiology line currently 
offered by the Company’s wholly-owned Warner Instruments and MCS subsidiaries. 

The aggregate purchase price for this acquisition was allocated to tangible and intangible assets acquired as follows: 

Tangible assets ..............................................................................................................................................   $ 
Liabilities assumed ........................................................................................................................................     
Net assets .......................................................................................................................................................     

   (in thousands) 
4,165   
(2,426 ) 
1,739   

Goodwill and intangible assets: 
Goodwill ........................................................................................................................................................     
Trade name ....................................................................................................................................................     
Customer relationships ..................................................................................................................................     
Developed technology ...................................................................................................................................     
Non-compete agreements ..............................................................................................................................     
Deferred tax liabilities ...................................................................................................................................     
Total goodwill and intangible assets, net of tax ............................................................................................     
Acquisition purchase price ............................................................................................................................   $ 

1,668   
774   
1,627   
1,338   
27   
(1,245 ) 
4,189   
5,928   

F-16 

 
  
  
  
  
  
  
  
  
  
    
  
 
  
  
  
  
  
  
  
  
    
    
    
    
 
 
 
Goodwill recorded as a result of the acquisition of HEKA is not deductible for tax purposes. 

In the second quarter of 2016, an immaterial correction was made to the allocation of the aggregate purchase price to 
the tangible and intangible assets acquired to increase both accrued liabilities and goodwill by $50,000 as of June 30, 2016. 
This correction has been reflected in the table above. 

The results of operations for HEKA have been included in the Company’s consolidated financial statements from the 

date of acquisition. 

The following consolidated pro forma information is based on the assumption that the acquisition of HEKA occurred 
on January 1, 2015. Accordingly, the historical results have been adjusted to reflect amortization expense that would have 
been recognized on such a pro forma basis. The pro forma information is presented for comparative purposes only and is not 
necessarily indicative of the financial position or results of operations which would have been reported had we completed the 
acquisition during these periods or which might be reported in the future. 

Year Ended  
December 31, 
2015 
(in thousands) 

Pro Forma 

Revenues ..............................................................................................................................................   $ 
Net (loss) income .................................................................................................................................     

108,761   
(19,027 ) 

Direct  transaction  costs  recorded  in  other  expense,  net,  in  relation  to  all  current  or  prospective  acquisitions  in  the 
Company’s  consolidated  statements  of  operations  were  $0.5  million,  $0.1  million  and  $1.2  million  for  the  years  ended 
December 31, 2017, 2016 and 2015, respectively. 

8. 

Dispositions 

As further discussed in Note 25 (Subsequent Events) on January 22, 2018, the Company sold substantially all the assets 

of its wholly owned subsidiary, Denville Scientific, Inc. 

AHN Biotechnologie GmbH 

On  October  26,  2016,  the  Company  sold  the  operations  of  its  AHN  Biotechnologie  GmbH  subsidiary  (AHN),  a 
manufacturer of liquid handling products, located in Nordhausen, Germany for gross cash proceeds of approximately $1.7 
million. Proceeds received at closing, net of cash on hand, were approximately $1.4 million. The results of operations of 
AHN, through the date of sale, were reported in the Company’s consolidated statements of operations for the year ended 
December 31, 2016. 

As a result of the initiation of plans to sell the operations of AHN, during the third quarter of 2016, the Company 
evaluated  the  long-lived  assets  of  AHN  for  impairment,  pursuant  to  ASC  360-10.  Based  on  the  impairment  analysis, the 
carrying amount of the long-lived assets exceeded the fair value of the long-lived assets as determined using the probability 
weighted present value of future cash flows. Consequently, the Company recognized an impairment charge of $0.7 million 
for  the  year  ended  December  31,  2016  in  operating  expenses  within  its  statements  of  operations.  Of  the  overall  charge, 
approximately $0.1 million was allocated to AHN’s intangible assets (trade name and customer relationships), while $0.6 
million was allocated to its property, plant and equipment (machinery and equipment). 

F-17 

  
  
  
  
  
  
  
  
  
  
    
    
  
  
 
  
  
  
  
 
 
Upon the closing of the transaction, the Company recorded a loss on sale of $1.2 million for the year ended December 
31, 2016 in operating expenses within the statements of operations. On October 26, 2016, the major classes of assets and 
liabilities of AHN disposed of, including an allocation of goodwill, were comprised of the following: 

Assets 

Accounts receivable, net ............................................................................................................................   $ 
Inventory ...................................................................................................................................................     
Property, plant and equipment, net ............................................................................................................     
Amortizable intangibles, net ......................................................................................................................     
Allocation of goodwill ...............................................................................................................................     

279   
438   
919   
196   
484   

   (in thousands) 

Liabilities 

Accounts payable and accrued expenses ...................................................................................................   $ 

245   

9. 

Goodwill and Other Intangible Assets 

Intangible assets consist of the following: 

   December 31, 2017 

   December 31, 2016 

(in thousands) 

   Weighted 
Average 
Life 

   (a) 

Amortizable intangible assets: 
Existing technology .............................................     $16,173     $ 
Trade names ........................................................        7,646       
Distribution agreements/customer relationships .       23,744       
223       
Patents .................................................................       
Total amortizable intangible assets .....................       47,786     $ 

   Gross    

Accumulated 
Amortization    Gross    

Accumulated 
Amortization   

(13,179)    $ 15,082     $ 
(4,060)       7,379       
(14,413)      22,976       
204       
(31,826)      45,641     $ 

(174)      

(11,710)      
(3,479)      
(12,862)      
(119)      
(28,170)      

6.5 Years 
7.1 Years 
8.1 Years 
1.2 Years 

Indefinite-lived intangible assets: 
Goodwill ..............................................................       39,969       
Other indefinite-lived intangible assets ...............        1,244       
Total goodwill and other indefinite-lived 

         38,032       
          1,209       

intangible assets ...............................................       41,213       

         39,241       

Total intangible assets .........................................     $88,999       

       $ 84,882       

(a) Weighted average life as of December 31, 2017.   

The change in the carrying amount of goodwill for the years ended December 31, 2017 and 2016 is as follows: 

Balance at December 31, 2015 ..........................................................................................................................    $ 
Adjustment to purchase price allocation of prior year acquisition ................................................................      
Adjustment to goodwill for AHN disposition ...............................................................................................      
Effect of change in currency translation ........................................................................................................      
Balance at December 31, 2016 ..........................................................................................................................      
Effect of change in currency translation ........................................................................................................      
Balance at December 31, 2017 ..........................................................................................................................    $ 

   (in thousands) 
40,357  
50  
(484) 
(1,891) 
38,032  
1,937  
39,969  

F-18 

  
  
    
    
  
    
    
    
    
  
 
  
  
  
     
     
     
     
  
  
  
     
     
     
     
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
         
  
     
        
         
        
         
  
  
         
     
        
         
        
         
  
  
         
         
  
  
         
         
  
  
         
         
  
  
         
  
     
        
         
        
         
  
  
         
         
  
  
         
  
  
  
  
 
 
 
Intangible asset amortization expense was $2.4 million, $2.7 million and $2.8 million for the years ended December 
31, 2017, 2016 and 2015, respectively. Amortization expense of existing amortizable intangible assets is currently estimated 
to be $2.4 million for the year ending December 31, 2018, $2.2 million for the year ending December 31, 2019, $2.2 million 
for the year ending December 31, 2020, $2.2 million for the year ending December 31, 2021 and $2.1 million for the year 
ending December 31, 2022. 

10. 

Restructuring and Other Exit Costs 

During  2014  and  2015,  the  Company  entered  into  various  restructuring  plans,  which  included  eliminating  certain 
positions made redundant as a result of its site consolidations, as well as a realignment of its commercial sales team. These 
restructuring plans also included the relocation of the distribution operations of the Company’s Denville Scientific subsidiary 
from New Jersey to North Carolina, as well as the consolidation of the manufacturing operations of its Biochrom subsidiary 
to its headquarters in Holliston, MA. Activity and liability balances related to these charges for the year ended December 31, 
2016, were as follows: 

  Severance Costs   

Other 
(in thousands) 

Total 

Restructuring balance at December 31, 2015 .....................................   $ 
Restructuring charges .........................................................................     
Non-cash reversal of restructuring charges ........................................     
Cash payments....................................................................................     
Effect of change in currency translation .............................................     
Restructuring balance at December 31, 2016 .....................................   $ 

132    $ 
-      
(27)     
(104)     
(1)     
-    $ 

-    $
23      
-      
(28)     
5      
-    $

132   
23   
(27 ) 
(132 ) 
4   
-   

For the year ended December 31, 2015, the activity and liability balances related to these charges were as follows: 

  Severance Costs   

Other 
(in thousands) 

Total 

Restructuring balance at December 31, 2014 .....................................   $ 
Restructuring charges .........................................................................     
Non-cash reversal of restructuring charges ........................................     
Cash payments....................................................................................     
Effect of change in currency translation .............................................     
Restructuring balance at December 31, 2015 .....................................   $ 

626    $ 
434      
(85)     
(833)     
(10)     
132    $ 

-    $
439      
-      
(439)     
-      
-    $

626   
873   
(85 ) 
(1,272 ) 
(10 ) 
132   

Aggregate net restructuring charges for the years ended December 31, 2017, 2016 and 2015 were as follows: 

Restructuring (credits) charges ...........................................................   $ 

-    $ 

(4)   $

788   

2017 

Year Ended December 31, 
2016 
(in thousands) 

2015 

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11. 

Long Term Debt 

On August 7, 2009, the Company entered into an Amended and Restated Revolving Credit Loan Agreement related to 
a  $20.0  million  revolving  credit  facility  with  Bank  of  America,  as  agent,  and  Bank  of  America  and  Brown  Brothers 
Harriman & Co as lenders (as amended, the 2009 Credit Agreement). On March 29, 2013, the Company entered into a Second 
Amended and Restated Revolving Credit Agreement (as amended, the 2013 Credit Agreement) with Bank of America, as 
agent,  and  Bank  of  America  and  Brown  Brothers  Harriman &  Co,  as  lenders  that  amended  and  restated  the  2009  Credit 
Agreement. Between September 2011 and May 2017, the Company entered into a series of amendments that among other 
things did the following: 

• 

• 

• 

• 

• 

• 

• 

on September 30, 2011, reduced interest rates to the London Interbank Offered Rate plus 3.0%; 

on March 29, 2013, converted existing loan advances into a term loan in the principal amount of $15.0 million
(the 2013 Term Loan), provided a revolving credit facility in the maximum principal amount of $25.0 million
(the 2013 Revolving Line) and a delayed draw term loan (the 2013 DDTL) of up to $15.0 million; 

on October 31, 2013, reduced the 2013 DDTL from up to $15.0 million to up to $10.0 million; 

on April 24, 2015, extended the maturity date of the 2013 Revolving Line to March 29, 2018 and reduced the
interest rates on the 2013 Revolving Line, 2013 Term Loan and 2013 DDTL; 

on June 30, 2015, amended its quarterly minimum fixed charge coverage financial covenant; 

on March 9, 2016, amended the principal payment amortization of the 2013 Term Loan and 2013 DDTL to
five years, as well as amended its quarterly minimum fixed charge coverage financial covenant; and 

on May 2, 2017, entered into a Third Amended and Restated Revolving Credit Agreement (as amended, the
Credit Agreement) with Bank of America, as agent, and Bank of America and Brown Brothers Harriman &
Co, as lenders that amended and restated the 2013 Credit Agreement. 

The  Credit  Agreement  was  entered  into  to,  among  other  things,  consolidate,  combine  and  restate  the  outstanding 
indebtedness, on the date of the Credit Agreement, into a term loan (the Term Loan) in the principal amount of $14.0 million, 
and also provide for a $25.0 million revolving line of credit (the Revolving Line). The Term Loan and the Revolving Line 
each have a maturity date of May 1, 2022. Borrowings under the Term Loan accrue interest at a rate based on either the 
effective LIBOR for certain interest periods selected by the Company, or a daily floating rate based on the BBA LIBOR as 
published by Reuters (or other commercially available source providing quotations of BBA LIBOR), plus in either case, a 
margin of 2.75%. Additionally, the Revolving Line accrues interest at a rate based on either the effective LIBOR for certain 
interest periods selected by the Company, or a daily floating rate based on the BBA LIBOR, plus in either case, a margin of 
2.25%.  

The Term Loan and loans under the Revolving Line evidenced by the Credit Agreement, or the Loans, are guaranteed 
by all of the Company’s direct and indirect domestic subsidiaries, and secured by substantially all of the assets of the Company 
and the guarantors. The Loans are subject to restrictive covenants under the Credit Agreement, and financial covenants that 
require the Company and its subsidiaries to maintain certain financial ratios on a consolidated basis, including a maximum 
leverage, minimum fixed charge coverage and minimum working capital. Prepayment of the Loans is allowed by the Credit 
Agreement at any time during the terms of the Loans. The Loans also contain limitations on the Company’s ability to incur 
additional  indebtedness  and  requires  lender  approval  for  acquisitions  funded  with  cash,  promissory  notes  and/or  other 
consideration in excess of $6.0 million and for acquisitions funded solely with equity in excess of $10.0 million. 

As of December 31, 2017 and December 31, 2016, the Company had borrowings of $11.7 million and $13.7 million, 
net  of  deferred  financing  costs,  respectively,  outstanding  under  its  Credit  Agreement.  The  carrying  value  of  the  debt 
approximates fair value because the interest rate under the obligation approximates market rates of interest available to the 
Company for similar instruments. 

As of December 31, 2017, the weighted effective interest rates, net of the impact of the Company’s interest rate swaps, 

on its Term Loan was 4.61%. 

F-20 

 
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
 
 
As of December 31, 2017 and December 31, 2016, the Company’s borrowings were comprised of: 

   December 31,     December 31, 

2017 

2016 

(in thousands) 

Long-term debt: 

Term loan ....................................................................................................................   $ 
DDTL ..........................................................................................................................     
Revolving line .............................................................................................................     
Total unamortized deferred financing costs ................................................................     
Total debt ........................................................................................................................     
Less: current installments ............................................................................................     
Current unamortized deferred financing costs .............................................................     
Long-term debt ................................................................................................................   $ 

11,899    $ 
-      
-      
(151)     
11,748      
(2,800)     
35      
8,983    $ 

5,400   
4,400   
4,050   
(104 ) 
13,746   
(2,450 ) 
78   
11,374   

The aggregate amounts of debt maturing during the next five years are as follows: 

   (in thousands) 

2018 ...............................................................................................................................................................   $ 
2019 ...............................................................................................................................................................     
2020 ...............................................................................................................................................................     
2021 ...............................................................................................................................................................     
2022 ...............................................................................................................................................................     
Total ..............................................................................................................................................................   $ 

11,899   
-   
-   
-   
-   
11,899   

As  further  discussed  in  Note  25,  on  January  22,  2018,  the  Company  terminated  the  Credit  Agreement  and  all 
outstanding  amounts  under  the  agreement  were  repaid  in  full.  At  the  time  of  repayment,  there  was  approximately  $11.9 
million of debt balances outstanding. Accordingly, the table above reflects the repayment of the debt in 2018. Additionally, 
as further disclosed in Note 25, on January 31, 2018, the Company entered into a financing agreement with Cerberus Business 
Finance, LLC, which provided for a $64.0 million term loan and up to a $25.0 million revolving line of credit. The $64.0 
million term loan has a maturity of five years. The payment schedule of this financing agreement is detailed in Note 25. 

12. 

Derivatives 

The Company uses interest-rate-related derivative instruments to manage its exposure related to changes in interest 
rates on its variable-rate debt instruments. The Company does not enter into derivative instruments for any purpose other than 
cash flow hedging. The Company does not speculate using derivative instruments. 

By using derivative financial instruments to hedge exposures to changes in interest rates, the Company exposes itself 
to credit risk and market risk. Credit risk is the failure of the counterparty to perform under the terms of the derivative contract. 
When the fair value of a derivative contract is positive, the counterparty owes the Company, which creates credit risk for the 
Company. When the fair value of a derivative contract is negative, the Company owes the counterparty and, therefore, the 
Company is not exposed to the counterparty’s credit risk in those circumstances. The Company minimizes counterparty credit 
risk in derivative instruments by entering into transactions with carefully selected major financial institutions based upon 
their credit profile. 

Market risk is the adverse effect on the value of a derivative instrument that results from a change in interest rates. The 
market risk associated with interest-rate contracts is managed by establishing and monitoring parameters that limit the types 
and degree of market risk that may be undertaken. 

The Company assesses interest rate risk by continually identifying and monitoring changes in interest rate exposures 
that may adversely impact expected future cash flows and by evaluating hedging opportunities. The Company maintains risk 
management control systems to monitor interest rate risk attributable to both the Company’s outstanding or forecasted debt 
obligations as well as the Company’s offsetting hedge positions. The risk management control systems involve the use of 
analytical techniques, including cash flow sensitivity analysis, to estimate the expected impact of changes in interest rates on 
the Company’s future cash flows. 

F-21 

  
  
  
  
  
  
  
    
       
    
  
  
  
  
    
    
  
  
 
  
  
  
  
  
The  Company  uses  variable-rate  London  Interbank  Offered  Rate  (LIBOR)  debt  to  finance  its  operations.  The  debt 
obligations expose the Company to variability in interest payments due to changes in interest rates. Management believes 
that it is prudent to limit the variability of a portion of its interest payments. To meet this objective, management enters into 
LIBOR based interest rate swap agreements to manage fluctuations in cash flows resulting from changes in the benchmark 
interest rate of LIBOR. These swaps change the variable-rate cash flow exposure on the debt obligations to fixed cash flows. 
Under the terms of the interest rate swaps, the Company receives LIBOR based variable interest rate payments and makes 
fixed interest rate payments, thereby creating the equivalent of fixed-rate debt for the notional amount of its debt hedged. 

As disclosed in Note 11, on May 2, 2017, the Company entered into a Credit Agreement that amended its then existing 
credit  facility  with  Bank  of  America,  as  agent,  and  Bank  of  America  and  Brown  Brothers  Harriman  &  Co.  as  lenders. 
Immediately after entering into this Credit Agreement, the Company entered into an interest rate swap contract with Bank of 
America with a notional amount of $14.0 million and a termination date of March 30, 2022 in order to hedge the risk of 
changes in the effective benchmark interest rate (LIBOR) associated with the Company’s Term Loan. The swap contract 
converted specific variable-rate debt into fixed-rate debt and fixed the LIBOR rate associated with the Term Loan at 1.86% 
plus a bank margin of 2.75%. The interest rate swap was designated as a cash flow hedge instrument in accordance with ASC 
815 “Derivatives and Hedging”. 

The notional amount of the Company’s derivative instruments as of December 31, 2017 was $11.9 million. 

The  following  table  presents  the  notional  amount  and  fair  value  of  the  Company’s  derivative  instruments  as  of 

December 31, 2017 and December 31, 2016. 

 December 31, 2017  December 31, 2017
  Notional Amount   Fair Value (a) 

Derivatives designated as hedging instruments 
under ASC 815 
Interest rate swaps .....................................................   Other assets 

 Balance sheet classification 

  $ 

(in thousands) 
11,900 $ 

37  

 December 31, 2016  December 31, 2016
  Notional Amount   Fair Value (a) 

Derivatives designated as hedging instruments 
under ASC 815 
Interest rate swaps .....................................................   Other assets 

 Balance sheet classification 

(in thousands) 

  $ 

5,500 $ 

-  

(a) See Note 13 for the fair value measurements related to these financial instruments. 

All of the Company’s derivative instruments are designated as hedging instruments. 

The Company has structured its interest rate swap agreements to be 100% effective and as a result, there was no impact 
to  earnings  resulting  from  hedge  ineffectiveness.  Changes  in  the  fair  value  of  interest  rate  swaps  designated  as  hedging 
instruments that effectively offset the variability of cash flows associated with variable-rate, long-term debt obligations are 
reported in accumulated other comprehensive income (“AOCI”). These amounts subsequently are reclassified into interest 
expense as a yield adjustment of the hedged interest payments in the same period in which the related interest affects earnings. 
The Company’s interest rate swap agreement was deemed to be fully effective in accordance with ASC 815, and, as such, 
unrealized gains and losses related to these derivatives were recorded as AOCI. 

The  following  table  summarizes  the  effect  of  derivatives  designated  as  cash  flow  hedging  instruments  and  their 

classification within comprehensive loss for the years ended December 31, 2017, 2016 and 2015: 

Derivatives in Hedging Relationships 

Amount of gain or (loss) recognized in OCI  
on derivative (effective portion) 
Year Ended December 31, 
2016 
(in thousands) 

2015 

2017 

Interest rate swaps ..............................................................................   $

(24)   $ 

(29)   $

(85 ) 

F-22 

 
  
  
  
  
   
  
   
  
  
   
  
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
 
 
 
The following table summarizes the reclassifications out of accumulated other comprehensive loss for the years ended 

December 31, 2017, 2016 and 2015: 

Details about AOCI Components 

Amount reclassified from AOCI into  
income (effective portion) 
Year Ended December 31, 
2016 
(in thousands) 

2017 

2015 

Location of amount 
reclassified from AOCI 
 into income (effective portion)

Interest rate swaps .............................................  $ 

61  $ 

39  $ 

93   

Interest expense 

As of December 31, 2017, the deferred gains or losses on derivative instruments accumulated in AOCI expected to be 

reclassified to earnings during the next twelve months were immaterial. 

As disclosed in Note 25, on January 22, 2018, the Company terminated its Credit Agreement with Bank of America, 
as  agent,  and  Bank  of  America  and  Brown  Brothers  Harriman  &  Co.  as  lenders.  As  a  result  of  terminating  this  Credit 
Agreement,  the  Company  unwound  the  interest  rate  swap  contract  and  received  an  immaterial  amount  in  proceeds.  In 
addition, as further described in Note 25, in February 2018, the Company entered into a new interest rate swap agreement 
with PNC bank as a result of entering into the previously described financing agreement with Cerberus Financing LLC. . 

13. 

Fair Value Measurements 

Fair value measurement is defined as the price that would be received to sell an asset or paid to transfer a liability in 
the principal or most advantageous market for the asset or liability in an orderly transaction between market participants at 
the measurement date. A fair value hierarchy is established, which prioritizes the inputs used in measuring fair value into 
three broad levels as follows: 

Level 1—Quoted prices in active markets for identical assets or liabilities. 
Level 2—Inputs, other than the quoted prices in active markets, that are observable either directly or indirectly. 
Level 3—Unobservable inputs based on the Company’s own assumptions. 

The following tables present the fair value hierarchy for those liabilities measured at fair value on a recurring basis: 

(In thousands) 
Assets (Liabilities): 

Fair Value as of December 31, 2017 

Level 1 

Level 2 

Level 3 

Total 

Interest rate swap agreements ...........................   $ 

-    $ 

37     $ 

-    $ 

37   

(In thousands) 
Assets (Liabilities): 

Fair Value as of December 31, 2016 

Level 1 

Level 2 

Level 3 

Total 

Interest rate swap agreements ...........................   $

-     $

-    $ 

-    $

-   

The Company uses the market approach technique to value its financial liabilities. The Company’s financial liabilities 
carried at fair value include derivative instruments used to hedge the Company’s interest rate risks. The fair value of the 
Company’s interest rate swap agreements was based on LIBOR yield curves at the reporting date.  

14. 

Leases 

The Company has noncancelable operating leases for office and warehouse space expiring at various dates through 
2022 and thereafter. Rent expense, which is recorded on a straight-line basis, was $1.9 million, $1.8 million and $2.1 million 
for the years ended December 31, 2017, 2016 and 2015, respectively. 

F-23 

  
 
 
  
 
 
  
 
 
 
  
 
 
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
     
    
    
  
  
    
    
      
      
      
  
    
        
       
       
    
  
  
 
  
 
 
Future minimum lease payments for operating leases, with initial or remaining terms in excess of one year at 

December 31, 2017, are as follows: 

2018 ...............................................................................................................................................................   $
2019 ...............................................................................................................................................................     
2020 ...............................................................................................................................................................     
2021 ...............................................................................................................................................................     
2022 ...............................................................................................................................................................     
Thereafter ......................................................................................................................................................     
Net minimum lease payments .......................................................................................................................   $

Leases 
     (in thousands)   
1,744   
1,657   
1,501   
1,110   
1,089   
1,873   
8,974   

   Operating 

As  further  discussed  in  Note  25,  on  January  22,  2018,  the  Company  sold  substantially  all  the  assets  of  Denville 
Scientific, an operating subsidiary. Additionally, as discussed in Note 25, the Company acquired DSI in January 2018, and 
as such the table above, which is as of December 31, 2017 excludes both DSI and Denville’s future payments under operating 
leases. 

15. 

Accrued Expenses 

Accrued expenses consist of: 

Accrued compensation and payroll .................................................................................   $ 
Accrued professional fees ...............................................................................................     
Warranty costs .................................................................................................................     
Other ................................................................................................................................     
Total ................................................................................................................................   $ 

16. 

Income Tax 

December 31, 

2017 

2016 

(in thousands) 
1,772    $
580      
246      
1,953      
4,551    $

1,468   
1,105   
193   
1,784   
4,550   

Income tax expense attributable to income from operations for the years ended December 31, 2017, 2016 and 2015 consisted 
of: 

Current income tax expense: 

Federal and state .............................................................................   $
Foreign ...........................................................................................     

Deferred income tax (benefit) expense: 

Federal and state .............................................................................     
Foreign ...........................................................................................     

Total income tax (benefit) expense ....................................................   $

2017 

Year Ended December 31, 
2016 
(in thousands) 

2015 

262    $ 
297      
559      

(2,357)     
575      
(1,782)     
(1,223)   $ 

170    $
790      
960      

166      
103      
269      
1,229    $

(4 ) 
677   
673   

15,598   
(840 ) 
14,758   
15,431   

F-24 

  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
    
       
       
    
  
    
    
       
       
    
  
    
  
 
 
Income tax expense for the years ended December 31, 2017, 2016 and 2015 differed from the amount computed by 

applying the U.S. federal income tax rate of 34% to pre-tax operations income as a result of the following: 

2017 

Year Ended December 31, 
2016 
(in thousands) 

2015 

Computed "expected" income tax (benefit) expense ......................................    $ 

(710)   $ 

(1,046)   $ 

(1,227) 

Increase (decrease) in income taxes resulting from: 
Permanent differences, net .........................................................................      
Foreign tax rate differential .......................................................................      
State income taxes, net of federal income tax benefit ................................      
Non-deductible stock compensation expense ............................................      
Impact of foreign rate change ....................................................................      
Impact of U.S. rate change .........................................................................      
Tax credits .................................................................................................      
Change in reserve for uncertain tax position ..............................................      
Impact of change to prior year tax accruals ...............................................      
Impact of adoption of ASU 2016-09, Improvements to Employee  
Share-based Payment Accounting .............................................................      
U.S. tax on foreign dividends ....................................................................      
Foreign withholding taxes .........................................................................      
Conversion of U.S. foreign tax credits from credit to deduction ...............      
Non-deductible loss on subsidiary stock sale .............................................      
Change in valuation allowance allocated to income ..................................      
tax expense (benefit) ..................................................................................      
Other ..........................................................................................................      
Total income tax (benefit) expense ................................................................    $ 

(108)     
23      
(71)     
174      
-      
2,521      
(14)     
(58)     
72      

(486)     
3,149      
38      
648      
-      

(6,393)     
(8)     
(1,223)   $ 

(128)     
165      
(93)     
110      
30      
-      
(89)     
127      
291      

-      
497      
74      
1,772      
501      

(983)     
1      
1,229    $ 

32  
(12) 
82  
(161) 
89  
-  
(169) 
35  
370  

-  
-  
-  
-  
-  

16,401  
(9) 
15,431  

Income tax (benefit) expense is based on the following pre-tax loss from operations for the years ended December 31, 

2017, 2016 and 2015: 

2017 

Year Ended December 31, 
2016 
(in thousands) 

2015 

Domestic ........................................................................................................    $ 
Foreign ...........................................................................................................      
Total ...............................................................................................................    $ 

(3,129)   $ 
1,041      
(2,088)   $ 

(3,107)   $ 
29      
(3,078)   $ 

(3,331) 
(277) 
(3,608) 

The tax effects of temporary differences that give rise to significant components of the deferred tax assets and deferred 

tax liabilities from operations at December 31, 2017 and 2016 are as follows: 

Deferred tax assets: 

Accounts receivable ...................................................................................................................   $ 
Inventory....................................................................................................................................     
Operating loss and credit carryforwards ....................................................................................     
Property, plant and equipment ...................................................................................................     
Pension liabilities .......................................................................................................................     
Contingent consideration ...........................................................................................................     
Stock compensation expense .....................................................................................................     
Other assets ................................................................................................................................     
Total gross deferred assets .............................................................................................................     
Less: valuation allowance ..........................................................................................................     
Deferred tax assets .........................................................................................................................   $ 

Deferred tax liabilities: 

Indefinite-lived intangible assets ...............................................................................................   $ 
Definite-lived intangible assets ..................................................................................................     
Other accrued liabilities .............................................................................................................     
Total deferred tax liabilities ...........................................................................................................     
Net deferred tax liabilities ..............................................................................................................   $ 

F-25 

December 31, 

2017 

2016 

(in thousands) 

93     $ 
891       
8,287       
3       
151       
2,273       
1,667       
119       
13,484       
(11,447 )     
2,037     $ 

3,166     $ 
2,383       
270       
5,819       
(3,782 )   $ 

170   
1,336   
12,586   
5   
631   
3,262   
2,076   
23   
20,089   
(17,840 ) 
2,249   

4,567   
2,593   
349   
7,509   
(5,260 ) 

  
  
  
  
  
  
  
  
    
       
       
   
    
       
       
   
       
       
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
    
        
    
  
    
        
    
    
        
    
Certain prior year amounts in the above table have been reclassified for consistency with the current year presentation. 

These reclassifications had no effect on the Company’s consolidated financial statements. 

The Company adopted the provisions of ASU 2016-09, Improvements to Employee Share-based Payment Accounting, 
on January 1, 2017.  Upon adoption, the company recorded previously unrecognized excess tax benefits from the exercise of 
employee stock options as an increase in its deferred tax asset for net operating losses of approximately $0.5 million.  The 
tax benefit of this increased deferred tax asset is fully offset by an increase in the valuation allowance. Following adoption, 
excess  tax  benefits  or  tax  deficit  is  reflected  as  income  tax  benefit  or  expense  in  the  year  the  tax  impact  is  generated. 
Approximately $96 thousand of tax deficit was recorded as income tax expense in 2017. Prior to the adoption of ASU 2016-
09, these excess tax benefits could only be recognized when the related tax deduction reduces income taxes payable and the 
benefit would be reflected as a credit to additional paid-in capital if realized. 

The amounts recorded as deferred tax assets as of December 31, 2017 and 2016 represent the amount of tax benefits of 
existing deductible temporary differences and carryforwards that are more likely than not to be realized through the generation 
of  sufficient  future  taxable  income  within  the  carryforward  period.  Significant  management  judgment  is  required  in 
determining any valuation allowance recorded against deferred tax assets and liabilities. During the year ended December 
31, 2015, the Company determined that it was more likely than not that its U.S. deferred tax assets would not be realized and 
therefore recorded a net increase to the valuation allowance of $16.4 million to offset U.S. deferred tax assets net of deferred 
tax  liabilities  except  for  deferred  tax  liabilities  associated  with  certain  indefinite-lived  intangible  assets.  The  Company’s 
judgment was based on consideration of all available evidence. At December 31, 2017 and 2016, the Company continues to 
maintain  a  valuation  allowance  against  substantially  all  net  U.S.  deferred  tax  assets,  exclusive  of  deferred  tax  liabilities 
associated with certain indefinite-lived intangible assets. During the year ended December 31, 2017, the Company determined 
that it was more likely than not that deferred tax assets of certain foreign subsidiaries would not be realized and therefore 
recorded a valuation allowance of $0.5 million on net deferred tax assets. 

On December 22, 2017, tax reform legislation known as the Tax Cuts and Jobs Act (the Tax Act) was signed into law. 
The Tax Act makes broad and complex changes to the U.S. Internal Revenue Code, including the reduction of the corporate 
income tax rate from 35% to 21% and the implementation of a modified territorial tax system; the latter includes a one-time 
transition  tax  on  previously  unremitted  earnings  of  foreign  subsidiaries.  Recent  SEC  guidance  under  Staff  Accounting 
Bulletin No. 118, Income Tax Accounting Implications of the Tax Cuts and Jobs Act (SAB 118) provides for a measurement-
period approach for the recording of income tax effects related to tax reform for which the accounting is incomplete. The 
accounting for the impact of the Tax Act is incomplete, however the Company has recorded provisional estimates for the 
impact of changes related to the revaluation of deferred taxes, the impact of the mandatory repatriation of foreign earnings 
after electing the utilization of existing tax attributes, and for the reduction in valuation allowance on net federal deferred tax 
assets. Since these provisions were based on estimates, the Company will continue to measure the impact of these areas and 
record any changes in subsequent quarters when information and guidance become available. Those areas include the analysis 
of various elections available including the transition tax, state-tax impact and adoption by the various states, completion of 
foreign earnings and profits calculations and additional guidance from the Treasury on various provisions under the new law. 

Other  law  changes  implemented  by  the  Act  such  as  changes  to  the  calculation  for  Section  162(m)  executive 
compensation deduction, interest deduction limitation and Global Intangible Low Taxed Income (GILTI), and others will not 
have any impact on the Company until the year ended December 31, 2018. The Company will continue to monitor guidance 
regarding these changes for how it will impact the financial statements in later periods. 

At December 31, 2017, the Company had federal net operating loss carryforwards of $14.4 million, which begin to 
expire in 2021 and state net operating loss carryforwards of $8.6 million, which begin to expire in 2018. Approximately $8.0 
million of federal net operating loss carryforwards are expected to be utilized during 2017 to offset the transition impact. The 
Company also had research and development tax credit carryforwards of $1.7 million which begin to expire in 2020. The 
Company had $0.4 million of alternative minimum tax credit carryforwards which are not subject to expiration and become 
refundable under the Tax Act beginning in 2018 subject to sequestration. In addition, the Company had a total of $1.1 million 
of state investment tax credit carryforwards, research and development tax credit carryforwards, and EZ credit carryforwards, 
which begin to expire in 2018. Approximately $3.3 million of net operating losses are subject to an annual limitation of $0.7 
million imposed by change in ownership provisions of Section 382 of the Internal Revenue Code. As mentioned above, these 
net operating loss and credit carryforwards have full valuation allowances set up against them. 

F-26 

  
  
  
  
  
 
 
Undistributed earnings of the Company’s foreign subsidiaries amounted to approximately $49.2 million, $48.6 million, 
and $48.7 million at December 31, 2017, 2016 and 2015, respectively. As of December 31, 2017, the Company changed its 
indefinite reinvestment assertion to provide that all foreign earnings above the level required for local operating expenses 
would be repatriated to the U.S. in tax years after 2017. Prior to 2017, this modified assertion only applied to the Company’s 
subsidiaries in France and Canada. At December 31, 2017, as the Company was considering a potential U.S. acquisition, the 
Company changed its assertion and it was anticipated that U.S. needs would require repatriation of all foreign subsidiaries’ 
earnings rather than just France and Canada. As a result of the Tax Act, all prior unremitted earnings are deemed paid and 
included in the current provision under the one-time repatriation tax calculation. Therefore, as a result of the change in this 
assertion, only $38 thousand of additional withholding has been accrued as of December 31, 2017. 

In 2016, the Company recorded a tax reserve in the amount of $59 thousand related to the disposition of a foreign 
subsidiary. Additionally in 2016, the Company recorded a reserve for $62 thousand related to issues raised in an ongoing 
German income tax audit. In 2017, the Company recorded a $21 thousand adjustment to the reserve related to the disposition 
of a foreign subsidiary. Also in 2017, the German income tax audit was settled for $30 thousand and $32 thousand of the 
remaining reserve was reversed. A reconciliation of uncertain tax liabilities is as follows: 

Balance at December 31, 2015 ......................................................................................................................   $ 
Additions based on current year tax positions ...............................................................................................     
Additions based on tax positions of prior years ............................................................................................     
Balance at December 31, 2016 ......................................................................................................................     
Decreases based on tax positions of prior years ............................................................................................     
Settlements ....................................................................................................................................................     
Balance at December 31, 2017 ......................................................................................................................   $ 

   (in thousands) 
285   
59   
62   
406   
(53 ) 
(30 ) 
323   

At December 31, 2017 and 2016 the amount of unrecognized tax benefits that would affect the Company’s effective 
tax rate was $0.3 million and $0.4 million, respectively. The Company classifies interest and penalties related to unrecognized 
tax benefits as a component of income tax expense. For the years ended December 31, 2017 and 2016, respectively, interest 
recognized in the consolidated statement of operations was immaterial, and there were no penalties recognized. 

The Company or one of its subsidiaries files income tax returns in the U.S. federal jurisdiction, and various states and 
foreign jurisdictions. With few exceptions, the Company is no longer subject to income tax examinations by tax authorities 
in  foreign  jurisdictions  for  years  before  2013.  In  the  U.S.,  the  Company's  net  operating  loss  and  tax  credit  carryforward 
amounts remain subject to federal and state examination for tax years starting in 2000 as a result of tax losses incurred in 
prior years. There are currently no pending federal or state tax examinations. The Company is subject to audits by various 
taxing jurisdictions. Additional reserves are established when necessary. No ongoing audits are expected to have a material 
impact. 

17. 

Employee Benefit Plans 

The Company sponsors profit sharing retirement plans for its U.S. employees, which includes employee savings plans 
established under Section 401(k) of the U.S. Internal Revenue Code (the 401(k) Plans). The 401(k) Plans cover substantially 
all full-time employees who meet certain eligibility requirements. Contributions to the profit sharing retirement plans are at 
the  discretion  of  management.  For  the  years  ended  December  31,  2017,  2016  and  2015,  the  Company  contributed 
approximately $0.6 million, $0.6 million and $0.5 million, respectively, to the 401(k) Plans. 

The  Company’s  subsidiary  in  the  United  Kingdom,  Biochrom,  maintains  contributory,  defined  benefit  or  defined 
contribution pension plans for substantially all of its employees. These defined benefit pension plans have been closed to new 
employees since 2014, as well as closed to the future accrual of benefits for existing employees. The provisions of FASB 
ASC 715-20 require that the funded status of the Company’s pension plans be recognized in its balance sheet. FASB ASC 
715-20 does not change the measurement or income statement recognition of these plans, although it does require that plan 
assets and benefit obligations be measured as of the balance sheet date. The Company has historically measured the plan 
assets and benefit obligations as of the balance sheet date. 

F-27 

  
  
  
  
  
  
 
  
  
 
 
The components of the Company’s defined benefit pension expense were as follows: 

Components of net periodic benefit cost: 
Interest cost ........................................................................................   $
Expected return on plan assets ...........................................................     
Net amortization loss ..........................................................................     
Net periodic benefit cost .....................................................................   $

2017 

Year Ended December 31, 
2016 
(in thousands) 

2015 

524    $ 
(663)     
362      
223    $ 

632    $
(683)     
304      
253    $

711   
(668 ) 
306   
349   

The measurement date is December 31 for these plans. The funded status of the Company’s defined benefit pension 

plans and the amount recognized in the consolidated balance sheets at December 31, 2017 and 2016 is as follows: 

Change in benefit obligation: 

Balance at beginning of year .......................................................................................   $ 
Interest cost .................................................................................................................     
Actuarial loss ...............................................................................................................     
Benefits paid ................................................................................................................     
Currency translation adjustment ..................................................................................     
Balance at end of year .................................................................................................   $ 

19,214    $
524      
26      
(514)     
1,876      
21,126    $

18,582   
632   
4,636   
(982 ) 
(3,654 ) 
19,214   

December 31, 

2017 

2016 

(in thousands) 

December 31, 

2017 

2016 

(in thousands) 

Change in fair value of plan assets: 

Balance at beginning of year .......................................................................................   $ 
Actual return on plan assets .........................................................................................     
Employer contributions ...............................................................................................     
Benefits paid ................................................................................................................     
Currency translation adjustment ..................................................................................     
Balance at end of year .................................................................................................   $ 

16,252    $
1,871      
689      
(514)     
1,674      
19,972    $

15,767   
3,868   
694   
(982 ) 
(3,095 ) 
16,252   

Change in benefit obligation: 
Funded status ...................................................................................................................   $ 
Unrecognized net loss .....................................................................................................     
Net amount recognized ....................................................................................................   $ 

(1,154)   $
N/A      
(1,154)   $

(2,962 ) 
N/A   
(2,962 ) 

The accumulated benefit obligation for all defined benefit pension plans was $21.1 million and $19.2 million at 

December 31, 2017 and 2016, respectively. 

December 31, 

2017 

2016 

(in thousands) 

F-28 

  
  
  
  
  
  
  
  
  
    
    
    
  
  
  
  
  
  
  
  
  
    
       
    
  
  
  
  
  
  
  
  
  
   
 
  
  
  
  
  
  
  
  
    
       
    
  
 
 
The amounts recognized in the consolidated balance sheets consist of: 

December 31, 

2017 

2016 

(in thousands) 

Deferred income tax assets ..............................................................................................   $ 
Other long term liabilities ................................................................................................     
Net amount recognized ....................................................................................................   $ 

196    $
(1,154)     
(958)   $

504   
(2,962 ) 
(2,458 ) 

The amounts recognized in accumulated other comprehensive loss, net of tax consist of: 

Underfunded status of pension plans ...............................................................................   $ 
Net amount recognized ....................................................................................................   $ 

December 31, 

2017 

2016 

(in thousands) 
(958)   $
(958)   $

(2,458 ) 
(2,458 ) 

The weighted average assumptions used in determining the net pension cost for these plans follows: 

Year Ended December 31, 
2016 

2017 

2015 

Discount rate .....................................................................................     
Expected return on assets ..................................................................     

2.43%    
3.86%    

2.62%     
4.68%     

3.57%
4.43%

The discount rate assumptions used for pension accounting reflect the prevailing rates available on high-quality, fixed-
income debt instruments with terms that match the average expected duration of the Company’s defined benefit pension plan 
obligations. The Company uses the iBoxx AA 15yr+ index, which matches the average duration of its pension plan liability 
of approximately 15 years. With the current base of assets in the pension plans, a one percent increase/decrease in the discount 
rate assumption would decrease/increase annual pension expense by approximately $12,000. 

The Company’s mix of pension plan investments among asset classes also affects the long-term expected rate of return 
on plan assets. As of December 31, 2017, the Company’s actual asset mix approximated its target mix. Differences between 
actual and expected returns are recognized in the calculation of net periodic pension (income)/cost over the average remaining 
expected future working lifetime, which is approximately 15 years, of active plan participants. With the current base of assets, 
a  one  percent  increase/decrease  in  the  asset  return  assumption  would  decrease/increase  annual  pension  expense  by 
approximately $200,000. 

The fair value and asset allocations of the Company’s pension benefits as of December 31, 2017 and 2016 measurement 

dates were as follows: 

Asset category: 

2017 

December 31, 

(in thousands) 

2016 

Equity securities ...............................................    $
Debt securities ..................................................      
Liability driven investment funds .....................      
Cash and cash equivalents ................................      
Other .................................................................      
Total .................................................................    $

10,774      
3,204      
4,685      
856      
453      
19,972      

54%  $
16%    
24%    
4%    
2%    
100%  $

8,577      
7,447      
-      
228      
-      
16,252      

53%
46%
0%
1%
0%
100%

F-29 

  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
    
       
        
       
   
 
 
 
Financial reporting standards define a fair value hierarchy that consists of three levels. The fair values of the plan assets 

by fair value hierarchy level as of December 31, 2017 and 2016 is as follows: 

December 31, 

2017 

2016 

(in thousands) 

Quoted Prices in Active Markets for Identical Assets (Level 1) .....................................   $ 
Significant Other Observable Inputs (Level 2) ................................................................     
Significant Other Unobservable Inputs (Level 3) ............................................................     
Total ............................................................................................................................   $ 

856    $
19,116      
-      
19,972    $

228   
16,024   
-   
16,252   

Level 1 assets consist of cash and cash equivalents held in the pension plans at December 31, 2017. The Level 2 assets 
primarily consist of investments in private investment funds that are valued using the net asset values provided by the trust 
or fund, including an insurance contract. Although these funds are not traded in an active market with quoted prices, the 
investments underlying the net asset value are based on quoted prices. 

The Company expects to contribute approximately $0.7 million to its pension plans during 2018. 

The benefits expected to be paid from the pension plans are $0.5 million in 2018, $0.6 million in 2019, $0.6 million in 
2020, $0.6 million in 2021 and $0.7 million in 2022. The expected benefits to be paid in the five years from 2023—2027 are 
$4.2 million. The expected benefits are based on the same assumptions used to measure the Company’s benefit obligation at 
December 31, 2017. 

18. 

Commitments and Contingent Liabilities 

From time to time, the Company may be involved in various claims and legal proceedings arising in the ordinary course 

of business. The Company is not currently a party to any such material claims or proceedings. 

19. 

Capital Stock 

Common Stock  

On February 5, 2008, the Company’s Board of Directors adopted a Shareholder Rights Plan and declared a dividend 
distribution of one preferred stock purchase right for each outstanding share of the Company’s common stock to shareholders 
of record as of the close of business on February 6, 2008. Initially, these rights would not be exercisable and would trade with 
the  shares  of  the  Company’s  common  stock.  Under  the  Shareholder  Rights  Plan,  the  rights  generally  would  become 
exercisable if a person became an “acquiring person” by acquiring 20% or more of the common stock of the Company or if 
a person commences a tender offer that could result in that person owning 20% or more of the common stock of the Company. 
If a person became an acquiring person, each holder of a right (other than the acquiring person) would be entitled to purchase, 
at the then-current exercise price, such number of shares of preferred stock which are equivalent to shares of the Company’s 
common stock having a value of twice the exercise price of the right. If the Company were acquired in a merger or other 
business combination transaction after any such event, each holder of a right would then be entitled to purchase, at the then-
current exercise price, shares of the acquiring company’s common stock having a value of twice the exercise price of the 
right. The Shareholder Rights Plan expired in accordance with its terms on the close of business on February 6, 2018. 

Preferred Stock 

The Company’s Board of Directors has the authority to issue up to 5.0 million shares of preferred stock and to determine 
the price privileges and other terms of the shares. The Board of Directors may exercise this authority without any further 
approval of stockholders. As of December 31, 2017, the Company had no preferred stock issued or outstanding. 

Employee Stock Purchase Plan (as amended, the “ESPP”) 

In 2000, the Company approved the ESPP. Under this ESPP, participating employees can authorize the Company to 
withhold  a  portion  of  their  base  pay  during  consecutive  six-month  payment  periods  for  the  purchase  of  shares  of  the 
Company’s common stock. At the conclusion of the period, participating employees can purchase shares of the Company’s 
common stock at 85% of the lower of the fair market value of the Company’s common stock at the beginning or end of the 
period.  Shares  are  issued  under  the  ESPP  for  the  six-month  periods  ending  June 30  and  December 31.  Under  this  plan, 
1,050,000 shares of common stock are authorized for issuance of which 801,454 shares were issued as of December 31, 2017. 

F-30 

  
  
  
  
  
  
  
  
  
  
  
  
 
  
  
 
  
  
  
  
  
  
During the years ended December 31, 2017, 2016 and 2015, the Company issued 76,215 shares, 81,228 shares and 58,823 
shares, respectively, of the Company’s common stock under the ESPP. 

Third Amended and Restated 2000 Stock Option and Incentive Plan (as amended, the “Third A&R Plan”) 

The Second Amendment to the Third A&R Plan (the “Amendment”) was adopted by the Board of Directors on April 3, 
2015. Such Amendment was approved by the stockholders at the Company’s 2015 Annual Meeting of Stockholders. Pursuant 
to the Amendment, the aggregate number of shares authorized for issuance under the Third A&R Plan was increased by 
2,500,000 shares to 17,508,929. 

Through December 31, 2017, 2016 and 2015, incentive stock options to purchase 10,218,057 shares and non-qualified 
stock options to purchase 13,369,074, 13,131,374 and 13,088,374 shares, respectively, had been granted to employees and 
directors under the Stock Plans. Generally, both the incentive stock options and non-qualified stock options become fully 
vested over a range of one to four-year periods. 

Restricted Stock Units with a Market Condition (the “Market Condition RSU’s”) 

On August 3, 2015, the Compensation Committee of the Board of Directors of the Company approved and granted 
deferred stock awards of Market Condition RSU’s to members of the Company’s management team under the Third A&R 
Plan. The vesting of these Market Condition RSU’s is cliff-based and linked to the achievement of a relative total shareholder 
return of the Company’s common stock from August 3, 2015 to the earlier of (i) August 3, 2018 or (ii) upon a change of 
control (measured relative to the Russell 3000 index and based on the 20-day trading average price before each such date). 
As of December 31, 2017, the target number of these restricted stock units that may be earned is 164,127 shares; the maximum 
amount is 150% of the target number. 

Stock-Based Payment Awards 

The Company accounts for stock-based payment awards in accordance with the provisions of FASB ASC 718, which 
requires it to recognize compensation expense for all stock-based payment awards made to employees and directors including 
stock options, restricted stock units, Market Condition RSU’s and employee stock purchases related to the ESPP. 

FASB ASC 718 requires companies to estimate the fair value of stock-based payment awards, except restricted stock 
units, on the date of grant using an option-pricing model. The value of the award is recognized as expense as it vests over the 
requisite service periods in the Company’s consolidated statements of operations. 

The Company adopted ASU 2016-09 as of January 1, 2017. As disclosed in footnote 2, as a result of this adoption, the 
Company  has  elected  as  an  accounting  policy  to  account  for  forfeitures  for  service  based  awards  as  they  occur,  with  no 
adjustment for estimated forfeitures. The Company recognized as of January 1, 2017, a cumulative effect adjustment of $0.1 
million to reduce retained earnings as required under the modified retrospective approach. 

The Company values stock-based payment awards, except restricted stock units, using the Black-Scholes option-pricing 
model. The Company values the Market Condition RSU’s using a Monte-Carlo valuation simulation. The determination of 
fair  value  of  stock-based  payment  awards  on  the  date  of  grant  using  an  option-pricing  model  or  Monte-Carlo  valuation 
simulation is affected by its stock price as well as assumptions regarding certain variables. These variables include, but are 
not limited to its expected stock price volatility over the term of the awards and actual and projected stock option exercise 
behaviors. The Company records stock compensation expense on a straight-line basis over the requisite service period for all 
awards granted since the adoption of FASB ASC 718. 

Earnings per share 

Basic  earnings  per  share  is  based  upon  net  income  divided  by  the  number  of  weighted  average  common  shares 
outstanding during the period. The calculation of diluted earnings per share assumes conversion of stock options, restricted 
stock units and Market Condition RSU’s into common stock using the treasury method. The weighted average number of 
shares used to compute basic and diluted earnings per share consists of the following: 

Year Ended December 31, 
2016 

2017 

2015 

Basic ..............................................................................................................     
Effect of assumed conversion of employee and director stock options, 

restricted stock units and Market Condition RSU's ....................................     
Diluted ...........................................................................................................     

34,753,325      

34,211,521      

33,592,775  

-      
34,753,325      

-      
34,211,521      

-  
33,592,775  

F-31 

  
  
  
  
  
  
  
    
    
  
  
Excluded from the shares used in calculating the diluted earnings per common share in the above table are options, 
restricted stock units and Market Condition RSU’s of approximately 5,741,298, 5,351,261 and 5,521,283 shares of common 
stock for the years ended December 31, 2017, 2016 and 2015, respectively, as the impact of these shares would be anti-
dilutive. 

General Option Information 

The following is a summary of stock option and the restricted stock unit activity: 

Stock Options 

  Restricted Stock Units 

  Market Condition RSU's 

Stock 
  Options 
  Outstanding   Price 

 Weighted    
  Average   Restricted    
  Exercise   Stock Units    Grant Date Condition RSU's   Grant Date
   Fair Value 

 Outstanding    Fair Value   Outstanding 

Market 

Balance at December 31, 2014 .......     6,263,112    $ 
Granted .......................................    
945,000      
Exercised ....................................     (1,772,062)    
-      
Vested (RSUs) ............................    
(413,864)    
Cancelled / forfeited ...................    
Balance at December 31, 2015 .......     5,022,186      
43,000      
(374,772)    
-      
(593,596)    
Balance at December 31, 2016 .......     4,096,818      
237,700      
(143,391)    
-      
(410,883)    
Balance at December 31, 2017 .......     3,780,244    $ 

Granted .......................................    
Exercised ....................................    
Vested (RSUs) ............................    
Cancelled / forfeited ...................    

Granted .......................................    
Exercised ....................................    
Vested (RSUs) ............................    
Cancelled / forfeited ...................    

3.42      306,397      $ 
5.31      254,685     
-     
3.04     
-      (237,188)   
(10,335)   
4.15     
3.85      313,559     
3.10      1,095,190     
-     
2.80     
-      (301,520)   
3.84     
(34,576)   
3.94      1,072,653     
3.24      1,298,371     
-     
2.48     
-      (488,570)   
(85,527)   

3.93     
3.95      1,796,927      $ 

4.30      
5.56      
-      
5.65      
5.56      
5.29      
2.92      
-      
4.45      
3.89      
3.15      
2.49      
-      
3.08      
3.05      
2.69      

-      $ 

196,785     
-     
-     
(11,247)    
185,538     
-     
-     
-     
(3,388)    
182,150     
-     
-     
-     
(18,023)    
164,127      $ 

-  
4.81  
-  
-  
4.81  
4.81  
4.81  
-  
-  
4.81  
4.81  
-  
-  
-  
4.81  
4.81  

The Company’s policy is to issue stock available from its registered but unissued stock pool through its transfer agent 

to satisfy stock option exercises and vesting of the restricted stock units. 

The  following  table  summarizes  information  concerning  currently  outstanding  and  exercisable  options  as  of 

December 31, 2017 (Aggregate Intrinsic Value, in thousands): 

Options Outstanding 

Options Exercisable 

  Weighted 
Average 

   Weighted 
Average 

Range of 
Exercise 
Price 

Shares 

  Weighted   
  Average   Aggregate 
  Outstanding at   Contractual Life   Exercise    Intrinsic    Exercisable at   Contractual Life   Exercise    Intrinsic 
   Dec. 31, 2017   

 Weighted   
  Average   Aggregate   

  Dec. 31, 2017   

   Remaining 

  Remaining 

   Value 

   Value 

in Years 

in Years 

   Price 

  Price 

Shares 

$2.02-2.37 .............     
2.38-2.94 ...............     
2.95-3.59 ...............     
3.60-3.95 ...............     
3.96-4.11 ...............     
4.12-4.17 ...............     
4.18-4.26 ...............     
4.27-4.41 ...............     
4.42-5.51 ...............     
5.52-5.63 ...............     
$2.02-5.63 .............     

415,024  
357,095  
321,239  
277,429  
252,282  
607,875  
71,500  
750,000  
462,300  
265,500  
3,780,244  

1.22  
4.78  
7.89  
5.47  
3.49  
6.41  
6.66  
5.88  
7.14  
7.41  
5.61  

 $ 

 $ 

2.20     $ 
2.58       
3.30       
3.65       
4.04       
4.12       
4.21       
4.31       
5.37       
5.56       
3.95     $ 

457       
257       
-       
-       
-       
-       
-       
-       
-       
-       

415,024  
315,845  
79,039  
273,679  
250,782  
452,750  
55,500  
750,000  
273,175  
132,750  
714        2,998,544  

1.22  
4.25  
2.93  
5.46  
3.47  
6.41  
6.63  
5.88  
7.11  
7.41  
5.02  

  $ 

  $ 

2.20     $ 
2.57       
3.35       
3.65       
4.04       
4.12       
4.21       
4.31       
5.31       
5.56       
3.84     $ 

457  
231  
-  
-  
-  
-  
-  
-  
-  
-  
688  

F-32 

  
  
  
  
 
  
   
  
  
   
  
  
  
 
  
 
  
  
  
  
  
 
  
 
  
 
  
  
  
 
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
   
    
    
    
    
  
    
 
  
  
  
  
  
  
  
    
   
   
    
    
    
    
    
   
    
   
   
    
    
   
   
    
    
   
   
    
    
   
   
    
    
   
   
    
    
   
   
    
    
   
   
    
    
   
   
    
    
   
   
    
    
   
    
 
 
 
The aggregate intrinsic value in the preceding table represents the total pre-tax intrinsic value, based on the Company’s 
closing stock price of $3.30 as of December 31, 2017, which would have been received by the option holders had all option 
holders exercised their options as of that date. The aggregate intrinsic value of options exercised for the years ended December 
31, 2017 and 2016 was approximately $0.1 million, respectively. The aggregate intrinsic value of options exercised for the 
year  ended  December  31,  2015  was  $0.8  million.  The  total  number  of  in-the-money  options  that  were  exercisable  as  of 
December 31, 2017 was 824,869. 

For the year ended December 31, 2017, the total compensation costs related to unvested awards not yet recognized is 

$4.0 million and the weighted average period over which it is expected to be recognized is 2.18 years. 

Valuation and Expense Information under Stock-Based-Payment Accounting 

Stock-based compensation expense related to stock options, restricted stock units, Market Condition RSU’s and the 

employee stock purchase plan for the years ended December 31, 2017, 2016 and 2015 was allocated as follows: 

2017 

Year Ended December 31, 
2016 
(in thousands) 

2015 

Cost of revenues .................................................................................   $
Sales and marketing ...........................................................................     
General and administrative .................................................................     
Research and development .................................................................     
Total stock-based compensation.........................................................   $

63    $ 
595      
2,703      
139      
3,500    $ 

60    $
546      
2,780      
111      
3,497    $

70   
418   
2,170   
97   
2,755   

On  April  28,  2015,  the  Company  announced  the  appointment  of  James  Green  to  its  Board  of  Directors  and  the 
retirement of Robert Dishman from its Board of Directors. As part of Dr. Dishman’s retirement, the Company (i) awarded an 
unrestricted stock award to Dr. Dishman on April 28, 2015, having an aggregate cash value of $80,000, (ii) accelerated the 
vesting of all outstanding stock options and restricted stock units that were unvested as of April 28, 2015, and (iii) extended 
the post-retirement option exercise period for each option to the earlier to occur of the respective scheduled expiration date 
or April 28, 2016. Total compensation expense recognized as part of general and administrative expenses for the year ended 
December 31, 2015, as part of these modifications, was approximately $0.1 million. 

The Company did not capitalize any stock-based compensation. 

The weighted-average estimated fair value per share of stock options granted during 2017, 2016 and 2015 was $1.32, 
$1.21  and  $2.12,  respectively,  using  the  Black  Scholes  option-pricing  model  with  the  following  weighted-average 
assumptions: 

Volatility ............................................................................................     
Risk-free interest rate .........................................................................     
Expected holding period (in years) .....................................................      5.41 years 
Dividend yield ....................................................................................     

-% 

Year Ended December 31, 
2016 
41.97% 
1.29% 

2015 
40.97% 
1.72% 

2017 
41.63% 
2.03% 

       5.21 years 

       5.50 years 

-% 

-% 

F-33 

  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
    
  
  
  
  
  
  
  
  
  
  
     
     
 
     
     
 
  
      
      
  
 
 
 
The weighted average fair value of the Market Condition RSU’s granted under the Third A&R Plan during the year 
ended December 31, 2015 was $4.81. The following assumptions were used to estimate the fair value, using a Monte-Carlo 
valuation simulation, of the Market Condition RSU’s granted during the year ended December 31, 2015: 

   Year Ended 
   December 31, 

2015 

Volatility .......................................................................................................................................................     
Risk-free interest rate ....................................................................................................................................     
Correlation coefficient ...................................................................................................................................     
Dividend yield ...............................................................................................................................................     

35.88% 
0.99% 
0.25% 
-% 

The Company used historical volatility to calculate the expected volatility as of December 31, 2017. Historical volatility 
was  determined  by  calculating  the  mean  reversion  of  the  daily  adjusted  closing  stock  price.  The  risk-free  interest  rate 
assumption is based upon observed U.S. Treasury bill interest rates (risk-free) appropriate for the term of the Company’s 
stock  options.  The  expected  holding  period  of  stock  options  represents  the  period  of  time  options  are  expected  to  be 
outstanding and were based on historical experience. The vesting period ranges from one to four years and the contractual 
life is ten years. 

Stock-based  compensation  expense  recognized  in  the  consolidated  statements  of  operations  for  the  years  ended 
December 31, 2017, 2016 and 2015 is recognized on awards as they vest and was reduced for annualized estimated forfeitures 
of 0.00%, 8.41% and 8.06%, respectively. As previously noted, the Company adopted ASU 2016-09 as of January 1, 2017, 
and  accordingly  recorded  a  cumulative  effect  adjustment  for  this  adoption.  As  of  that  date  onward,  the  Company  has 
accounted for forfeitures as they occur. Prior to the adoption of ASU 2016-09, stock-based-payment accounting required 
forfeitures to be estimated at the time of grant and revised, if necessary, in subsequent periods if actual forfeitures differ from 
those estimates. 

20. 

Related Party Transactions 

As part of the acquisitions of MCS and Triangle BioSystems, Inc. (TBSI), the Company signed lease agreements with 
the former owners of the acquired companies. The principals of such former owners were employees of the Company as of 
December 31, 2017. Pursuant to a lease agreement, the Company incurred rent expense of approximately $0.2 million to the 
former owners of MCS for each of the years ended December 31, 2017 and 2016 and 2015, respectively. Pursuant to a lease 
agreement, the Company incurred rent expense of approximately $42,000 to the former owner of TBSI for each of the years 
ended December 31, 2017 and 2016 and 2015, respectively. 

21. 

Segment and Related Information 

Operating segments are determined by products and services provided by each segment, internal organization structure, 
the manner in which operations are managed, criteria used by the Chief Operating Decision Maker, or CODM, to assess the 
segment performance, as well as resource allocation and the availability of discrete financial information. The Company has 
one operating segment. As such, segment results and consolidated results are the same. 

The following tables summarize selected financial information of the Company’s continuing operations by geographic 

location: 

Revenues originating from the following geographic areas consist of: 

United States ......................................................................................   $
Germany .............................................................................................     
United Kingdom .................................................................................     
Rest of the world ................................................................................     
Total revenues ....................................................................................   $

2017 

Year Ended December 31, 
2016 
(in thousands) 

2015 

66,198    $ 
11,162      
15,042      
9,480      
101,882    $ 

65,179    $
13,477      
16,421      
9,444      
104,521    $

64,766   
15,755   
18,051   
10,092   
108,664   

F-34 

  
  
  
  
  
  
  
  
 
  
  
 
  
  
  
  
  
  
  
  
  
  
  
  
 
 
 
Long-lived assets by geographic area consist of the following: 

December 31, 

2017 

2016 

(in thousands) 

United States ...................................................................................................................   $ 
Germany ..........................................................................................................................     
United Kingdom ..............................................................................................................     
Rest of the world .............................................................................................................     
Total long-lived assets (1) ...............................................................................................   $ 

10,127    $
5,793      
966      
3,214      
20,100    $

12,004   
5,504   
918   
3,341   
21,767   

(1) Total long-lived assets includes property, plant and equipment, net and amortizable intangible assets, net. 

Net assets by geographic area consist of the following: 

December 31, 

2017 

2016 

(in thousands) 

United States ...................................................................................................................   $ 
Germany ..........................................................................................................................     
United Kingdom ..............................................................................................................     
Rest of the world .............................................................................................................     
Total net assets ................................................................................................................   $ 

30,698    $
18,354      
14,376      
17,472      
80,900    $

22,312   
18,512   
17,908   
18,866   
77,598   

22. 

Allowance for Doubtful Accounts 

Allowance for doubtful accounts is based on the Company’s assessment of the collectability of customer accounts. A 

rollforward of allowance for doubtful accounts is as follows: 

   Beginning   
   Balance 

Charged (credited) to 
   Charged to   
   Ending 
 Expense (Recoveries)   Allowance (1)  Other (2)     Balance 

Bad Debt 

Year ended December 31, 2015 ................    $ 
Year ended December 31, 2016 ................    $ 
Year ended December 31, 2017 ................    $ 

328     
310     
611     

(4)      
309       
(109)      

4     
11     
(68)    

(18)   $ 
(19)   $ 
20    $ 

310  
611  
454  

(in thousands) 

(1) Consists of accounts written off, net of recoveries. 
(2) Consists of the effect of currency translation. 

23. 

Warranties 

Warranties are estimated and accrued at the time revenues are recorded. A rollforward of the Company’s product 

warranty accrual is as follows: 

   Beginning 
   Balance 

   Payments 

   Additions/ 
(Credits) 

Ending 
   Balance 

(in thousands) 

Year ended December 31, 2015 ...........................................   $ 

252       

(81)     

(24)   $ 

Year ended December 31, 2016 ...........................................   $ 

147       

(97)     

143    $ 

Year ended December 31, 2017 ...........................................   $ 

193       

(7)     

60    $ 

147  

193  

246  

F-35 

  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
 
  
  
  
  
  
  
  
  
  
  
    
   
    
   
    
  
  
 
  
  
  
  
  
  
  
  
  
  
  
    
    
    
    
  
    
        
       
       
   
  
    
        
       
       
   
  
 
 
24. 

Quarterly Financial Information (unaudited) 

Statement of Operations Data: 

2017 

First 
Quarter 

Second 
Quarter 

Third 
Quarter 
(in thousands, except per share data) 

Fourth 
Quarter 

Fiscal 
Year 

Revenues ............................................................    $ 
Cost of revenues .................................................      
Gross profit ....................................................      
Total operating expenses ....................................      
Operating (loss) income .....................................      
Other (expense) ..................................................      
Loss before income taxes ...................................      
Income tax expense (benefit) .............................      
Net (loss) income ...............................................    $ 

24,156    $ 
12,657      
11,499      
12,138      
(639)     
(404)     
(1,043)     
23      
(1,066)   $ 

25,213    $ 
13,926      
11,287      
11,286      
1      
(463)     
(462)     
(81)     
(381)   $ 

25,050    $ 
13,411      
11,639      
11,775      
(136)     
(274)     
(410)     
7      
(417)   $ 

27,463     $ 
14,291       
13,172       
12,499       
673       
(846 )     
(173 )     
(1,172 )     
999     $ 

101,882  
54,285  
47,597  
47,698  
(101) 
(1,987) 
(2,088) 
(1,223) 
(865) 

Loss per share: 

Basic (loss) earnings per common share ........    $ 

(0.03)   $ 

(0.01)   $ 

(0.01)   $ 

0.03     $ 

(0.02) 

Diluted (loss) earnings per common share .....    $ 

(0.03)   $ 

(0.01)   $ 

(0.01)   $ 

0.03     $ 

(0.02) 

F-36 

 
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
    
    
    
    
    
  
    
       
       
       
        
   
    
       
       
       
        
   
  
    
       
       
       
        
   
  
    
       
       
       
        
   
  
 
 
Statement of Operations Data: 

2016 

First 
Quarter 

Second 
Quarter 

Third 
Quarter 
(in thousands, except per share data) 

Fourth 
Quarter 

Fiscal 
Year 

Revenues ............................................................    $ 
Cost of revenues .................................................      
Gross profit ....................................................     
Total operating expenses ....................................      
Operating loss ....................................................      
Other (expense) income, net ...............................      
Loss before income taxes ...................................      
Income tax expense (benefit) .............................      
Net loss ..............................................................    $ 

26,963     $ 
14,018       
12,945       
13,166       
(221 )     
(222 )     
(443 )     
193       
(636 )   $ 

26,136    $ 
14,461      
11,675      
12,515      
(840)     
73      
(767)     
(54)     
(713)   $ 

25,007    $ 
13,317      
11,690      
12,503      
(813)     
(67)     
(880)     
758      
(1,638)   $ 

26,415    $ 
14,310      
12,105      
13,228      
(1,123)     
135      
(988)     
332      
(1,320)   $ 

104,521  
56,106  
48,415  
51,412  
(2,997) 
(81) 
(3,078) 
1,229  
(4,307) 

Loss per share: 

Basic loss per common share .........................   $ 

(0.02 )   $ 

(0.02)   $ 

(0.05)   $ 

(0.04)   $ 

(0.13) 

Diluted loss per common share ......................   $ 

(0.02 )   $ 

(0.02)   $ 

(0.05)   $ 

(0.04)   $ 

(0.13) 

25. 

Subsequent Events 

Denville Transaction 

On January 22, 2018, the Company sold substantially all the assets of its wholly owned subsidiary, Denville Scientific, 
Inc. (Denville), for approximately $20.0 million, which includes a $3.0 million earn-out provision (the Denville Transaction). 
Upon the closing of the transaction, the Company received $17.0 million. The remaining $3.0 million represents consideration 
that is contingent on Denville achieving certain performance metrics over a period of two years. Denville is a Charlotte, North 
Carolina-based life science research consumables distributor. The results of operations and financial position of Denville 
have been reported in the Company’s consolidated statements of operations and balance sheet for all periods presented. 

As a result of the Company’s initiation of plans to sell the operations of Denville during the fourth quarter of 2017, 
management  conducted  an  evaluation  of  Denville’s  assets  for  impairment.  Based  on  this  evaluation,  which  consisted  of 
comparing  the  probable  cash  flows  to  the  net  book  value  of  the  assets,  management  concluded  that  the  assets  were  not 
impaired. 

As of December 31, 2017, the major classes of assets and liabilities of Denville, which were reported in the Company’s 

consolidated balance sheet, were comprised of the following: 

Assets 
Accounts receivable, net .................................................................................................................................................    $ 
Inventory .........................................................................................................................................................................      
Property, plant and equipment, net ..................................................................................................................................      
Amortizable intangible assets, net ...................................................................................................................................      

Liabilities 
Accounts payable and accrued expenses .........................................................................................................................    $ 

(in thousands) 

2,854  
4,457  
396  
5,930  

1,720  

Termination of Third Amended and Restated Credit Agreement 

On January 22, 2018, in connection with the closing of the Denville Transaction, the Company terminated the Third 
Amended and Restated Credit Agreement, dated as of May 1, 2017, among the Company, Brown Brothers Harriman & Co. 
and each of the other lenders party thereto, and Bank of America, as administrative agent. All outstanding amounts under the 
agreement were repaid in full using a portion of the proceeds of the Denville Transaction. At the time of repayment, there 
was approximately $11.9 million outstanding. 

Interest Rate Swap 

As a result of terminating the Third Amended and Restated Credit Agreement, the Company unwound its existing 
swap agreement and received an immaterial amount of proceeds. On February 16, 2018, the Company entered into a new 

F-37 

  
  
  
  
  
  
  
  
  
  
  
  
  
  
    
    
    
    
    
  
    
        
       
       
       
   
    
        
       
       
       
   
  
    
        
       
       
       
   
  
    
        
       
       
       
   
 
  
  
    
   
  
    
   
    
   
interest rate swap contract with PNC bank with a notional amount of $36.0 million and a termination date of January 31, 
2023 in order to hedge the risk of changes in the effective benchmark interest rate (LIBOR) associated with the Financing 
Agreement (defined below). The swap contract converted specific variable-rate debt into fixed-rate debt and fixed the LIBOR 
rate associated with a portion of the term loan under the Financing Agreement at 2.72%. 

Data Sciences International Transaction 

On January 31, 2018, the Company acquired all of the issued and outstanding shares of Data Sciences International, 
Inc. (DSI), a Delaware corporation for approximately $70.0 million. The Company funded the acquisition from its existing 
cash balances, the remaining proceeds of the Denville Transaction and the proceeds of the Financing Agreement discussed 
below. 

DSI,  a  St.  Paul,  Minnesota-based  life  science  research  company,  is  a  recognized  leader  in  physiologic  monitoring 
focused  on  delivering  preclinical  products,  systems,  services  and  solutions  to  its  customers.  Its  customers  include 
pharmaceutical  and  biotechnology  companies,  as  well  as  contract  research  organizations,  academic  labs  and  government 
researchers.  This  acquisition  diversifies  the  Company’s  customer  base  into  the  biopharmaceutical  and  contract  research 
organization markets. 

The Company is in the process of determining the fair value of the various tangible and intangible assets acquired as 

a result of this acquisition. 

Financing Agreement 

On  January  31,  2018,  the  Company  entered  into  a  financing  agreement  by  and  among  the  Company  and  certain 
subsidiaries of the Company parties thereto, as borrowers (collectively, the Borrower), certain subsidiaries of the Company 
parties thereto, as guarantors, various lenders from time to time party thereto (the Lenders), and Cerberus Business Finance, 
LLC, as collateral agent and administrative agent for the Lenders (the Financing Agreement). 

The Financing Agreement provides for senior secured credit facilities (the Senior Secured Credit Facilities) comprised 
of a $64.0 million term loan and up to a $25.0 million revolving line of credit. The proceeds of the term loan and $4.8 million 
of advances under the revolving line of credit were used to fund a portion of the DSI acquisition, and to pay fees and expenses 
related thereto and the closing of the Senior Secured Credit Facilities. In addition, the revolving facility is available for use 
by  the  Company  and  its  subsidiaries  for  general  corporate  and  working  capital  needs,  and  other  purposes  to  the  extent 
permitted by the Financing Agreement. The Senior Secured Credit Facilities have a maturity of five years. At the closing date 
of  the  Financing  Agreement,  the  Company  had  approximately  $14.5  million  of  available  borrowing  capacity  under  the 
revolving line of credit. 

Commencing on March 31, 2018, the outstanding term loans will amortize in equal quarterly installments equal to 
$0.4 million per quarter on such date and during each of the next three quarters thereafter, $0.6 million per quarter during the 
next four quarters thereafter and $0.8 million per quarter thereafter, with a balloon payment at maturity. 

The  obligations  of  the  Borrower  under  the  Senior  Secured  Credit  Facilities  are  unconditionally  guaranteed  by  the 
Company and certain of the Company’s existing and subsequently acquired or organized subsidiaries. The Senior Secured 
Credit  Facilities  and  related  guarantees  are  secured  on  a  first-priority  basis  (subject  to  certain  liens  permitted  under  the 
Financing Agreement) by a lien on substantially all the tangible and intangible assets of the Borrower and the subsidiary 
guarantors, including all of the capital stock held by such obligors (subject to a 65% limitation on pledges of capital stock of 
foreign subsidiaries), subject to certain exceptions. 

Interest  on  all  loans  under  the  Senior  Secured  Credit  Facilities  is  paid  monthly.  Borrowings  under  the  Financing 
Agreement accrue interest at a per annum rate equal to, at the Borrower’s option, a base rate plus 4.75% or a LIBOR rate plus 
6.25%. The loans are also subject to a 1.25% interest rate floor for LIBOR loans and a 4.25% interest rate floor for base rate 
loans. 

The Financing Agreement contains customary representations and warranties and affirmative covenants applicable to 
the Company and its subsidiaries and also contains certain restrictive covenants, including, among others, limitations on the 
incurrence of additional debt, liens on property, acquisitions and investments, loans and guarantees, mergers, consolidations, 
liquidations  and  dissolutions,  asset  sales,  dividends  and  other  payments  in  respect  of  the  Company’s  capital  stock, 
prepayments of certain debt, transactions with affiliates and modifications of organizational documents, material contracts, 
affiliated  practice  agreements  and  certain  debt  agreements.  The  Financing  Agreement  also  contains  customary  events  of 
default. 

F-38 

 
 
Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly 

caused this report to be signed on its behalf by undersigned thereunto duly authorized.  

SIGNATURES 

Date: March 16, 2018 

HARVARD BIOSCIENCE, INC. 

By:  /s/ JEFFREY A. DUCHEMIN 

Jeffrey A. Duchemin 
Chief Executive Officer 

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, this report has been signed 

below by the following persons on behalf of the registrant and in the capacities and on the dates indicated: 

Signature 

Title 

Date 

/s/ JEFFREY A. DUCHEMIN 
Jeffrey A. Duchemin 

Chief Executive Officer and Director (Principal Executive Officer)  March 16, 2018 

/s/ ROBERT E. GAGNON 
Robert E. Gagnon 

Chief Financial Officer 
(Principal Financial Officer and Principal Accounting Officer) 

March 16, 2018 

/s/ JAMES GREEN 
James Green 

/s/ JOHN F. KENNEDY 
John F. Kennedy 

/s/ EARL R. LEWIS 
Earl R. Lewis 

/s/ BERTRAND LOY 
Bertrand Loy 

/s/ GEORGE UVEGES 
George Uveges 

Director 

Director 

Director 

Director 

Director 

/s/ THOMAS W. LOEWALD 
Thomas W. Loewald 

Director 

/s/ KATHERINE A. EADE 
Katherine A. Eade 

Director 

March 16, 2018 

March 16, 2018 

March 16, 2018 

March 16, 2018 

March 16, 2018 

March 16, 2018 

March 16, 2018 

 
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
 
 
 
EXHIBIT INDEX 

The  following  exhibits  are  filed  as  part  of  this  Annual  Report  on  Form  10-K.  Where  such  filing  is  made  by 

incorporation by reference to a previously filed document, such document is identified. 

Exhibit 
Number 

Description 

Method of Filing 

2.1§  Separation and Distribution Agreement between Harvard 
Bioscience, Inc. and Biostage, Inc. (f/k/a Harvard 
Apparatus Regenerative Technology, Inc.) dated as of 
October 31, 2013 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed November 6, 2013) and 
incorporated by reference thereto  

2.2§  Share Purchase Agreement between Biochrom Limited, as 

Buyer, and Multi-Channel Systems Holding GmbH, as 
Seller, dated as of October 1, 2014  

2.3§  Stock Purchase Agreement by and among Harvard 

Bioscience, Inc., as Buyer, Triangle BioSystems, Inc., and 
the sellers party thereto dated as of October 1, 2014 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed October 1, 2014) and 
incorporated by reference thereto 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed October 1, 2014) and 
incorporated by reference thereto 

2.4§  Agreement for the Sale and Purchase of All Shares in 
HEKA GmbH by and among Multi Channel Systems 
MCS GmbH, as Purchaser, Dr. Peter Schulze GmbH & 
Co. KG, as Seller, and Dr. Peter Schulze, as Guarantor, 
dated as of January 8, 2015 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed January 9, 2015) and 
incorporated by reference thereto 

2.5§  Agreement for the Sale and Purchase of All Shares in 
HEKA Canada between Ealing Scientific Limited, as 
Purchaser, and Dr. Peter Schulze, as Seller, dated as of 
January 8, 2015 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed January 9, 2015) and 
incorporated by reference thereto 

2.6§  Merger Agreement, dated as of January 22, 2018, between 

Harvard Bioscience, Inc., Plymouth Sub, Inc. and Data 
Sciences International, Inc. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed January 26, 2018) and 
incorporated by reference thereto 

2.7§  Purchase Agreement, dated as of January 22, 2018, 

between Harvard Bioscience, Inc., Denville Scientific, 
Inc. and Thomas Scientific, LLC 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed January 26, 2018) and 
incorporated by reference thereto 

3(i) 

Second Amended and Restated Certificate of 
Incorporation of Harvard Bioscience, Inc.  

3(ii)  Amended and Restated By-laws of Harvard 

Bioscience, Inc.  

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form S-1/A (File No. 333-45996) (filed on 
November 9, 2000) and incorporated by reference thereto  

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form S-1/A (File No. 333-45996) (filed on 
November 9, 2000) and incorporated by reference thereto 

3.1  Amendment No. 1 to Amended and Restated Bylaws of 
Harvard Bioscience, Inc. (as adopted October 30, 2007) 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed on November 1, 2007) and 
incorporated by reference thereto 

3.2  Certificate of Designations, Preferences and Rights of a 

Series of Preferred Stock of Harvard Bioscience, Inc. 
classifying and designating the Series A Junior 
Participating Cumulative Preferred Stock 

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form 8-A (filed February 8, 2008) and 
incorporated by reference thereto 

3.3  Certificate of Elimination of Series A Junior Participating 
Cumulative Preferred Stock, dated as of February 27, 
2018  

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form 8-A/A (filed March 2, 2018) and 
incorporated by reference thereto 

 
  
  
 
  
  
    
  
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
  
    
 
 
   
  
  
    
  
  
    
4.1 

Specimen certificate for shares of Common Stock, $0.01 
par value, of Harvard Bioscience, Inc.  

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form S-1/A (File No. 333-45996) (filed on 
November 9, 2000) and incorporated by reference thereto  

4.2  Amended and Restated Securityholders’ Agreement dated 

as of March 2, 1999 by and among Harvard 
Apparatus, Inc., Pioneer Partnership II, Pioneer Capital 
Corp., First New England Capital, L.P. and Citizens 
Capital, Inc. and Chane Graziano and David Green 

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form S-1/A (File No. 333-45996) (filed on 
October 25, 2000) and incorporated by reference thereto 

4.3 

Shareholders Rights Agreement, dated as of February 5, 
2008 between Harvard Bioscience, Inc., and Registrar and 
Transfer Company, as Rights Agent  

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form 8-A (filed February 8, 2008) and 
incorporated by reference thereto 

10.1  Harvard Apparatus, Inc. 1996 Stock Option and Grant 

Plan 

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form S-1/A (File No. 333-45996) (filed on 
October 25, 2000) and incorporated by reference thereto 

10.2  Harvard Bioscience, Inc. Third Amended and Restated 

2000 Stock Option and Incentive Plan  

  Previously disclosed in the Company’s Proxy Statement on 
Schedule 14A (filed April 15, 2011) and incorporated by 
reference thereto  

10.3  Harvard Bioscience, Inc. Employee Stock Purchase Plan 

10.4  Form of Director Indemnification Agreement  

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form S-1/A (File No. 333-45996) (filed on 
November 9, 2000) and incorporated by reference thereto 

  Previously filed as an exhibit to the Company’s Registration 
Statement on Form S-1/A (File No. 333-45996) (filed on 
October 25, 2000) and incorporated by reference thereto  

10.5  Lease of Unit 22 Phase I Cambridge Science Park, Milton 
Road, Cambridge dated May 8, 2008 between The Master 
Fellows and Scholars of Trinity College Cambridge and 
Biochrom Limited. 

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 11, 2009) and 
incorporated by reference thereto 

10.6  Lease, dated February 23, 2004, by and between William 

Cash Forman and Hoefer, Inc.  

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 15, 2004) and 
incorporated by reference thereto  

10.7 +  Trademark License Agreement, dated December 19, 2002, 

by and between Harvard Bioscience, Inc. and President 
and Fellows of Harvard College.  

10.8  Lease Agreement Between Seven October Hill, LLC and 
Harvard Bioscience, Inc. dated December 30, 2005. 

10.9  Form of Incentive Stock Option Agreement (Executive 

Officers). 

10.10  Form of Non-Qualified Stock Option Agreement 

(Executive Officers). 

10.11  Form of Non-Qualified Stock Option Agreement (Non-

Employee Directors).   

  Previously filed as an exhibit to the Company’s Quarterly 
Report on Form 10-Q (filed May 15, 2003) and incorporated 
by reference thereto 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed January 4, 2006) and 
incorporated by reference thereto 

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 16, 2006) and 
incorporated by reference thereto 

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 16, 2006) and 
incorporated by reference thereto  

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 16, 2006) and 
incorporated by reference thereto 

 
  
  
  
    
  
  
    
  
  
    
  
  
  
    
  
  
  
    
  
 
 
   
  
  
    
  
  
    
  
  
  
    
 
 
   
 
 
   
10.12  Amended and Restated Revolving Credit Loan 

Agreement, dated as of August 7, 2009, by and among 
Harvard Bioscience, Inc. and the Lenders from time to 
time party thereto, including Bank of America, N.A. (both 
in its capacity as “Lender” and in its capacity as “Agent”), 
and Brown Brothers Harriman & Co. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed August 13, 2009) and 
incorporated by reference thereto 

10.13  Amendment No. 2, dated as of May 22, 2010, to Lease 
Agreement, as subsequently amended, between Seven 
October Hill LLC and Harvard Bioscience, Inc. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed June 3, 2010) and incorporated 
by reference thereto 

10.14  Form of Deferred Stock Award Agreement under the 

Harvard Bioscience, Inc. Second Amended and Restated 
2000 Stock Option And Incentive Plan, as amended 

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 16, 2011) and 
incorporated by reference thereto 

10.15  Director Compensation Arrangements 

  Filed with this report 

10.16  Amendment No. 1 to the Harvard Bioscience, Inc. 

Employee Stock Purchase Plan, effective as of January 1, 
2012  

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 14, 2014) and 
incorporated by reference thereto 

10.17  First Amendment to Harvard Bioscience, Inc. Third 

Amended and Restated 2000 Stock Option and Incentive 
Plan, effective as of March 9, 2013 

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 14, 2014) and 
incorporated by reference thereto 

10.18  Second Amended and Restated Revolving Credit 

Agreement, dated as of March 29, 2013, by and among 
Harvard Bioscience, Inc. and the Lenders from time to 
time party thereto, including Bank of America, N.A. and 
Brown Brothers Harriman & Co. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed April 3, 2013) and incorporated 
by reference thereto 

10.19  Amendment No. 2 to the Harvard Bioscience, Inc. 

Employee Stock Purchase Plan, effective as of May 23, 
2013  

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 14, 2014) and 
incorporated by reference thereto 

10.20  First Amendment to Second Amended and Restated Credit 

Agreement dated as of May 30, 2013, with an effective 
date as of April 30, 2013, by and among Harvard 
Bioscience, Inc. Bank of America, N.A. and Brown 
Brothers Harriman & Co.  

10.21 #  Employment Agreement, dated August 26, 2013, between 
Harvard Bioscience, Inc. and Jeffrey A. Duchemin  

10.22 #  Offer letter dated September 30, 2013 between Harvard 

Bioscience, Inc. and Yong Sun 

10.23 #  Employment Agreement, dated October 2, 2013, between 
Harvard Bioscience, Inc. and Robert E. Gagnon 

10.24  Second Amendment to Second Amended and Restated 
Credit Agreement and Waiver dated as of October 31, 
2013, by and among Harvard Bioscience, Inc. Bank of 
America, N.A. and Brown Brothers Harriman & Co. 

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 14, 2014) and 
incorporated by reference thereto 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed August 29, 2013) and 
incorporated by reference thereto 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed February 19, 2014) and 
incorporated by reference thereto 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed October 16, 2013) and 
incorporated by reference thereto 

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 14, 2014) and 
incorporated by reference thereto 

10.25 

Intellectual Property Matters Agreement between Harvard 
Bioscience, Inc. and Biostage, Inc. (f/k/a Harvard 
Apparatus Regenerative Technology, Inc.) dated as of 
October 31, 2013. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed November 6, 2013) and 
incorporated by reference thereto 

 
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
 
 
   
  
  
    
  
  
    
  
  
    
  
  
    
10.26  Product Distribution Agreement between Harvard 
Bioscience, Inc. and Biostage, Inc. (f/k/a Harvard 
Apparatus Regenerative Technology, Inc.) dated as of 
October 31, 2013. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed November 6, 2013) and 
incorporated by reference thereto 

10.27  Tax Sharing Agreement between Harvard Bioscience, Inc. 
and Biostage, Inc. (f/k/a Harvard Apparatus Regenerative 
Technology, Inc.) dated as of October 31, 2013. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed November 6, 2013) and 
incorporated by reference thereto 

10.28  Transition Services Agreement between Harvard 
Bioscience, Inc. and Biostage, Inc. (f/k/a Harvard 
Apparatus Regenerative Technology, Inc.) dated as of 
October 31, 2013. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed November 6, 2013) and 
incorporated by reference thereto 

10.29 #  Amendment to Employment Agreement between Harvard 
Bioscience, Inc. and Jeffrey A. Duchemin, effective July 
30, 2014. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed July 31, 2014) and incorporated 
by reference thereto 

10.30 #  Amendment to Employment Agreement between Harvard 
Bioscience, Inc. and Robert E. Gagnon, effective July 30, 
2014. 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed July 31, 2014) and incorporated 
by reference thereto 

10.31  Amendment No. 3, dated as of May 30, 2014, to Lease 
Agreement, as subsequently amended, between Seven 
October Hill LLC and Harvard Bioscience, Inc. 

  Previously filed as an exhibit to the Company’s Quarterly 
Report on Form 10-Q (filed August 7, 2014) and 
incorporated by reference thereto 

10.32 #  Second Amendment to Employment Agreement, dated as 
of March 1, 2015, between Harvard Bioscience, Inc. and 
Jeffrey A. Duchemin 

  Previously filed as an exhibit to the Company’s Quarterly 
Report on Form 10-Q (filed May 7, 2015) and incorporated 
by reference thereto 

10.33  Third Amendment to Second Amended and Restated 

Credit Agreement and Waiver dated as of April 24, 2015, 
by and among Harvard Bioscience, Inc. Bank of America, 
N.A. and Brown Brothers Harriman & Co. 

10.34  Fourth Amendment to Second Amended and Restated 

Credit Agreement and Waiver dated as of June, 30, 2015, 
by and among Harvard Bioscience, Inc. Bank of America, 
N.A. and Brown Brothers Harriman & Co. 

  Previously filed as an exhibit to the Company’s Quarterly 
Report on Form 10-Q (filed August 6, 2015) and 
incorporated by reference thereto 

  Previously filed as an exhibit to the Company’s Quarterly 
Report on Form 10-Q (filed August 6, 2015) and 
incorporated by reference thereto 

10.35  Form of Deferred Stock Award Agreement under the 

Harvard Bioscience, Inc. Third Amended and Restated 
2000 Stock Option And Incentive Plan, as amended 

  Previously filed as an exhibit to the Company’s Quarterly 
Report on Form 10-Q (filed November 5, 2015) and 
incorporated by reference thereto 

10.36  Fifth Amendment to Second Amended and Restated 

Credit Agreement and Waiver dated as of November 5, 
2015, by and among Harvard Bioscience, Inc. Bank of 
America, N.A. and Brown Brothers Harriman & Co. 

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed April 29, 2016) and 
incorporated by reference thereto 

10.37  Sixth Amendment to Second Amended and Restated 
Credit Agreement dated as of March 9, 2016, by and 
among Harvard Bioscience, Inc. Bank of America, N.A. 
and Brown Brothers Harriman & Co. 

  Previously filed as an exhibit to the Company’s Quarterly 
Report on Form 10-Q (filed May 16, 2016) and incorporated 
by reference thereto 

10.38  Limited Consent and Waiver dated as of May 5, 2016 by 

and among Harvard Bioscience, Inc., Bank of America, 
N.A and Brown Brothers Harriman & Co. 

  Previously filed as an exhibit to the Company’s Quarterly 
Report on Form 10-Q (filed August 4, 2016) and 
incorporated by reference thereto 

10.39 #  Third Amendment to Employment Agreement, dated as of 

May 26, 2016, between Harvard Bioscience, Inc. and 
Jeffrey A. Duchemin 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed May 27, 2016) and incorporated 
by reference thereto 

 
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
 
 
   
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
10.40 #  Second Amendment to Employment Agreement, dated as 

of May 26, 2016, between Harvard Bioscience, Inc. and 
Robert E. Gagnon 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed May 27, 2016) and incorporated 
by reference thereto 

10.41 #  Employment Agreement, dated as of May 26, 2016, 

between Harvard Bioscience, Inc. and Yong Sun 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed May 27, 2016) and incorporated 
by reference thereto 

10.42  Limited Consent and Waiver dated as of November 1, 

2016, and effective as of October 26, 2016 by and among 
Harvard Bioscience, Inc., Bank of America, N.A and 
Brown Brothers Harriman & Co. 

  Previously filed as an exhibit to the Company’s Annual 
Report on Form 10-K (filed March 17, 2017) and 
incorporated by reference thereto 

10.43  Lease Agreement, dated as of August 15, 2008, between 

  Filed with this report 

AX US L.P. (as assigned to it by New Brighton 14th Street 
LLC), Ryan Companies US, Inc. and Data Sciences 
International, Inc. (as assigned to it by Transoma Medical, 
Inc.) 

10.44  First Amendment to Lease Agreement, dated as of 

  Filed with this report 

February 26, 2008, between AX US L.P. (as assigned to it 
by New Brighton 14th Street LLC), Ryan Companies US, 
Inc. and Data Sciences International, Inc. (as assigned to it 
by Transoma Medical, Inc.)   

10.45  Second Amendment to Lease Agreement, dated as of 

  Filed with this report 

August 4, 2008, between AX US L.P. (as assigned to it by 
New Brighton 14th Street LLC), Ryan Companies US, Inc. 
and Data Sciences International, Inc. (as assigned to it by 
Transoma Medical, Inc.) 

10.46  Financing Agreement, dated as of January 31, 2018, 

between Harvard Bioscience, Inc., each of the borrowers 
named therein, the lenders from time to time party thereto, 
and Cerberus Business Finance, LLC 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed February 2, 2018) and 
incorporated by reference thereto 

16.1  Letter from KPMG to the Securities and Exchange 

Commission, dated as of May 9, 2017 

  Previously filed as an exhibit to the Company’s Current 
Report on Form 8-K (filed May 11, 2017) and incorporated 
by reference thereto 

21.1  Subsidiaries of the Registrant 

23.1  Consent of Grant Thornton LLP 

23.2  Consent of KPMG LLP 

31.1  Certification of Chief Financial Officer of Harvard 

Bioscience, Inc., pursuant to Rules 13a-15(e) and 15d-
15(e), as adopted pursuant to Section 302 of the Sarbanes-
Oxley Act of 2002 

  Filed with this report 

  Filed with this report 

  Filed with this report 

  Filed with this report 

31.2  Certification of Chief Executive Officer of Harvard 

Bioscience, Inc., pursuant to Rules 13a-15(e) and 15d-
15(e), as adopted pursuant to Section 302 of the Sarbanes-
Oxley Act of 2002 

  Filed with this report 

32.1  Certification of Chief Financial Officer of Harvard 

Bioscience, Inc., pursuant to 18 U.S.C. Section 1350, as 
adopted pursuant to Section 906 of the Sarbanes-Oxley 
Act of 2002 

  *  

 
  
  
    
  
  
    
  
  
    
  
  
    
 
 
   
 
 
   
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
32.2  Certification of Chief Executive Officer of Harvard 

Bioscience, Inc., pursuant to 18 U.S.C. Section 1350, as 
adopted pursuant to Section 906 of the Sarbanes-Oxley 
Act of 2002 

  * 

101.INS XBRL Instance Document 

  Filed with this report 

101.SCH XBRL Taxonomy Extension Schema Document 

  Filed with this report  

101.CAL XBRL Taxonomy Extension Calculation Linkbase 

  Filed with this report  

Document 

101.DEF XBRL Taxonomy Extension Definition Linkbase 

  Filed with this report  

Document 

101.LAB XBRL Taxonomy Extension Label Linkbase Document 

  Filed with this report  

101.PRE XBRL Taxonomy Extension Presentation Linkbase 

  Filed with this report  

Document 

+ 

* 

# 
§ 

Certain portions of this document have been granted confidential treatment by the Securities and Exchange Commission
(the Commission). 
This  certification  shall  not  be  deemed  “filed”  for  purposes  of  Section 18  of  the  Securities  Exchange  Act  of  1934,  or 
otherwise subject to the liability of that section, nor shall it be deemed to be incorporated by reference into any filing under 
the Securities Act of 1933 or the Securities Exchange Act of 1934 
Management contract or compensatory plan or arrangement. 
The  schedules  and  exhibits  to  the  Separation  and  Distribution  Agreement  have  been  omitted.  A  copy  of  any  omitted
schedule or exhibit will be furnished to the SEC supplementally upon request. 

The Company will furnish to stockholders a copy of any exhibit without charge upon written request. 

 
  
  
  
  
  
  
  
  
  
  
 
Exhibit 10.15 

Compensation of Non-Employee Directors Upon Initial Election to the Board 

Director Compensation Arrangements 

Each non-employee director will be entitled to receive a non-qualified stock option having an aggregate Black-Scholes 
cash value of $120,000, rounded to the nearest 100 shares, provided that in no case shall such stock option be less than 25,000 
shares (so long as 25,000 shares are required to be granted under the equity incentive plan of the Corporation). Such option shall 
be for the purchase of common stock of the Corporation and shall vest annually over three years and be granted on the fifth 
business day following his or her initial election to the Board. 

Annual Compensation of Non-Employee Directors 

The annual retainers described herein shall each be satisfied by the issuance of deferred stock awards of restricted stock 
units (each a “Retainer Award”) in accordance herewith. Each non-employee director will be entitled to receive an annual retainer 
valued at $31,500. The Chairman will also be entitled to receive an additional annual retainer valued at $31,500. Each non-
employee director member of the Audit Committee will be entitled to receive an additional annual retainer valued at $8,100. 
Each non-employee director member of the Compensation Committee will be entitled to receive an additional annual retainer 
valued at $5,400. Each non-employee member of the Governance Committee will be entitled to receive an additional annual 
retainer valued at $4,500. The Committee Chairman of the Audit Committee will be entitled to receive an additional annual 
retainer valued at $16,200. The Committee Chairman of the Compensation Committee will be entitled to receive an additional 
annual  retainer  valued  at  $10,800.  The  Committee  Chairman  of  the  Governance  Committee  will  be  entitled  to  receive  an 
additional  annual  retainer  valued  at  $4,500.  The  Retainer  Awards  for  individuals  that  are  non-employee  directors  of  the 
Corporation as of the first trading day of January of the corresponding year, are granted on the first trading day of January (the 
“Grant Date”) and vest quarterly over the calendar year (on each March 31, June 30, September 30 and December 31, provided 
that in the event a director’s service (including as a Board member, or just role as Chairman, Committee Chairman, Committee 
member) ends during a particular quarter, the vesting date for such quarter in relation to the portion of the award attributable to 
such roles that are ending, shall be the last day of the director’s term in the respective role such that the full quarterly amount 
attributable to such roles shall vest on that earlier vesting date) and subject to continued service as a non-employee director on 
the applicable vesting dates) and subject to continued service as a non-employee director on the applicable vesting dates. The 
number of shares of common stock subject to a Retainer Award is equal to the amount of cash that would have been received 
had the retainers all been paid in cash, divided by the average daily closing market price of the common stock for the month of 
November, rounded to the nearest 100 shares. 

In the event that a non-employee director is named Chairman or joins any committees of the Board of Directors during 
a fiscal year after the Grant Date, such director shall be granted a Retainer Award (the “Additional Retainer Award”), in relation 
to such additional roles and respective retainer amounts pro-rated for the remainder of such year, on the first trading day of the 
month after the individual is appointed to such roles. The Additional Retainer Award shall vest in equal amounts spread over the 
remaining quarterly vesting dates of the Retainer Awards for such calendar year subject to continued service as a non-employee 
director on the applicable vesting dates, provided that in the event a director’s service (including as a Board member, or their 
role as Chairman, Committee Chairman, Committee member) ends during a particular quarter, the vesting date for such quarter 
in relation to the portion of the award attributable to such roles that are ending, shall be the last day of the director’s term in the 
respective role  such  that  the full quarterly amount  attributable  to  such  roles  shall vest  on  that  earlier  vesting  date  (i.e.  if  the 
Additional Retainer Award is granted on September 1, one half would vest on September 30 and the remaining half would vest 
on December 31). The number of shares of common stock subject to an Additional Retainer Award is equal to the amount of 
cash that would have been received had the retainers all been paid in cash, divided by the average daily closing market price of 
the common stock for the calendar month that is two months prior to the month the director was appointed to the additional roles, 
rounded to the nearest 100 shares (i.e., the month of June if the director was appointed to the additional roles on August 15). 

Each non-employee director will also be entitled to receive an equity award having an aggregate cash value of $72,000, 
rounded to the nearest 100 shares, vesting fully on the earlier to occur of (i) the date of the Corporation’s next Annual Meeting 
of Stockholders after the grant date, immediately prior to the commencement of such meeting, and (ii) one year from the date of 
grant and granted on the fifth business day following the Corporation’s Annual Meeting of Stockholders, with such award to be 
evidenced by a grant of deferred stock awards of restricted stock units. In addition, non-employee directors shall be reimbursed 
for their expenses incurred in connection with attending Board and Committee meetings. 

 
  
  
  
  
  
  
  
 
Exhibit 21.1 

Subsidiaries of the Registrant 

AHN Acquisition GmbH (Germany) 
Asys Hitech GmbH (Austria) 
Biochrom Limited (United Kingdom) 
Biochrom US, Inc. (United States) 
BioDrop Ltd. (United Kingdom) 
Cartesian Technologies, Inc. (United States) 
CMA Microdialysis AB (Sweden) 
Coulbourn Instruments, LLC (United States) 
Denville  Scientific,  Inc.  (now  known  as  Harvard  Distribution  Oldco,  Inc.  following  name  change  after  December  31,  2017) 
(United States) 
Ealing Scientific Limited (doing business as Harvard Apparatus, Canada) (Canada) 
FKA GSI US, Inc. (formerly Genomic Solutions, Inc.) (United States) 
FKAUBI, Inc. (formerly Union Biometrica, Inc.) (United States) 
Genomic Solutions Canada, Inc. (United States) 
Harvard Apparatus Limited (United Kingdom) 
Harvard Apparatus, S.A.R.L. (France) 
HEKA Electronics Incorporated (Canada) 
HEKA Electronik Dr. Schulze GmbH (Germany) 
HEKA Instruments Incorporated (United States) 
Hoefer, Inc. (United States) 
Hugo Sachs Elektronik - Harvard Apparatus GmbH (Germany) 
KD Scientific, Inc. (United States) 
Multi Channel Systems MCS GmbH (Germany) 
Panlab S.L. (Spain) 
Scie-Plas Ltd. (United Kingdom) 
Triangle BioSystems, Inc. (United States) 
Walden Precision Apparatus Ltd. (United Kingdom) 
Warner Instruments LLC (United States) 

*This list excludes the following entities which were not subsidiaries as of December 31, 2017 but are subsidiaries following the 
acquisition of Data Sciences International, Inc. in January 2018: 

Data Sciences International, Inc. 
Data Sciences (UK) MN, Ltd. 
Data Sciences EURL 
Data Sciences GmbH 
DSI (Shanghai) Trading Co Ltd. 

 
  
  
  
  
  
  
EXHIBIT 23.1 

Consent of Independent Registered Public Accounting Firm 

The Board of Directors 
Harvard Bioscience, Inc.: 

We have issued our reports dated March 16, 2018, with the respect to the consolidated financial statements and internal control 
over financial reporting included in the Annual Report of Harvard Bioscience, Inc. on Form 10-K for the year ended December 
31, 2017. We consent to the incorporation by reference of the said reports in the Registration Statements of Harvard Bioscience, 
Inc.  on  Form  S-3,  as  amended  (File  No.  333-203552)  and  Forms  S-8  (File  No.  333-53848,  File  No.  333-104544,  File  
No.  333-135418,  File  No.  333-151003,  File  No.  333-174476,  File  No.  333-189175,  File  No.  333-204760  and  
File No. 333-218497). 

/s/ GRANT THORNTON LLP 

Boston, Massachusetts 
March 16, 2018 

 
  
  
  
  
  
  
  
  
Consent of Independent Registered Public Accounting Firm 

EXHIBIT 23.2 

The Board of Directors 
Harvard Bioscience, Inc.: 

We  consent  to  the  incorporation  by  reference  in  the  Registration  Statement  Numbers  333-53848,  333-104544,  333-135418,  
333-151003, 333-174476, 333-189175, 333-204760 and 333-218497 on Form S-8, and 333-203552 on Form S-3, as amended, 
of Harvard Bioscience, Inc. and subsidiaries of our report dated March 16, 2017, with respect to the consolidated balance sheet 
of Harvard Bioscience, Inc. and subsidiaries as of December 31, 2016, and the related consolidated statements of operations, 
comprehensive  (loss)  income,  stockholders’  equity  and  cash  flows  for  each  of  the  years  in  the  two-year  period  ended 
December 31, 2016, which report appears in the December 31, 2017 annual report on Form 10-K of Harvard Bioscience, Inc. 

Cambridge, Massachusetts 
March 16, 2018 

/s/ KPMG LLP 

 
  
  
  
  
  
  
  
  
I, Robert E. Gagnon, certify that: 

Certification 

1.  I have reviewed this annual report on Form 10-K of Harvard Bioscience, Inc.; 

EXHIBIT 31.1 

2.  Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material
fact necessary to make the statements made, in light of the circumstances under which such statements were made, not
misleading with respect to the period covered by this report; 

3.  Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in
all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods
presented in this report; 

4.  The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and
procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e) and internal control over financial reporting (as
defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have: 

   a.  Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed
under  our  supervision,  to  ensure  that  material  information  relating  to  the  registrant,  including  its  consolidated
subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is 
being prepared; 

   b.  Designed such internal control over financial reporting, or caused such internal control over financial reporting to be
designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the 
preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

   c.  Evaluated  the  effectiveness  of  the  registrant’s  disclosure  controls  and  procedures  and  presented  in  this  report  our 
conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by
this report based on such evaluation; and 

   d.  Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the
registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has
materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting;
and 

5.  The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control
over  financial  reporting,  to  the  registrant’s  auditors  and  the  audit  committee  of  the  registrant’s  board  of  directors  (or
persons performing the equivalent functions): 

   a.  All  significant  deficiencies  and  material  weaknesses  in  the  design  or  operation  of  internal  control  over  financial
reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and
report financial information; and 

   b.  Any fraud, whether or not material, that involves management or other employees who have a significant role in the

registrant’s internal control over financial reporting. 

       Date: March 16,  2018 

/s/ ROBERT E. GAGNON 
Robert E. Gagnon 
Chief Financial Officer 

 
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
I, Jeffrey A. Duchemin, certify that: 

Certification 

1.  I have reviewed this annual report on Form 10-K of Harvard Bioscience, Inc.; 

EXHIBIT 31.2 

2.  Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material
fact necessary to make the statements made, in light of the circumstances under which such statements were made, not 
misleading with respect to the period covered by this report; 

3.  Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in
all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods
presented in this report; 

4.  The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and
procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e) and internal control over financial reporting (as
defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have: 

   a.  Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed
under  our  supervision,  to  ensure  that  material  information  relating  to  the  registrant,  including  its  consolidated
subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is 
being prepared; 

   b.  Designed such internal control over financial reporting, or caused such internal control over financial reporting to be
designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the
preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

   c.  Evaluated  the  effectiveness  of  the  registrant’s  disclosure  controls  and  procedures  and  presented  in  this  report  our 
conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by
this report based on such evaluation; and 

   d.  Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the
registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has
materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting;
and 

5.  The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control
over  financial  reporting,  to  the  registrant’s  auditors  and  the  audit  committee  of  the  registrant’s  board  of  directors  (or
persons performing the equivalent functions): 

   a.  All  significant  deficiencies  and  material  weaknesses  in  the  design  or  operation  of  internal  control  over  financial
reporting  which  are reasonable  likely  to  adversely  affect the  registrant’s  ability  to  record, process,  summarize  and
report financial information; and 

   b.  Any fraud, whether or not material, that involves management or other employees who have a significant role in the

registrant’s internal control over financial reporting. 

       Date:  March 16, 2018 

/s/ JEFFREY A. DUCHEMIN 
Jeffrey A. Duchemin 
Chief Executive Officer 

 
  
  
  
  
  
  
  
  
  
  
  
  
  
  
 
CERTIFICATION OF PERIODIC FINANCIAL REPORT 
PURSUANT TO 18 U.S.C. SECTION 1350 

EXHIBIT 32.1 

The  undersigned  officer  of  Harvard  Bioscience, Inc.  (the  “Company”)  hereby  certifies  to  his  knowledge  that  the 
Company’s annual report on Form 10-K for the year ended December 31, 2017 to which this certification is being furnished as 
an exhibit (the “Report”), as filed with the Securities and Exchange Commission on the date hereof, fully complies with the 
requirements of Section 13(a) or 15(d), as applicable, of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), 
and that the information contained in the Report fairly presents, in all material respects, the financial condition and results of 
operations  of  the  Company.  This  certification  is  provided  solely  pursuant  to  18  U.S.C.  Section 1350  and  Item 601(b)(32)  of 
Regulation S-K (“Item 601(b)(32)”) promulgated under the Securities Act of 1933, as amended (the “Securities Act”), and the 
Exchange Act. In accordance with clause (ii) of Item 601(b)(32), this certification (A) shall not be deemed “filed” for purposes 
of  Section 18  of  the  Exchange  Act,  or  otherwise  subject  to  the  liability  of  that  section,  and  (B) shall  not  be  deemed  to  be 
incorporated by reference into any filing under the Securities Act or the Exchange Act, except to the extent that the Company 
specifically incorporates it by reference. 

        Date: March 16,  2018 

/s/ ROBERT E. GAGNON 
Name: Robert E. Gagnon 
Title: Chief Financial Officer 

 
  
  
  
  
  
  
  
CERTIFICATION OF PERIODIC FINANCIAL REPORT 
PURSUANT TO 18 U.S.C. SECTION 1350 

EXHIBIT 32.2 

The  undersigned  officer  of  Harvard  Bioscience, Inc.  (the  “Company”)  hereby  certifies  to  his  knowledge  that  the 
Company’s annual report on Form 10-K for the year ended December 31, 2017 to which this certification is being furnished as 
an exhibit (the “Report”), as filed with the Securities and Exchange Commission on the date hereof, fully complies with the 
requirements of Section 13(a) or 15(d), as applicable, of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), 
and that the information contained in the Report fairly presents, in all material respects, the financial condition and results of 
operations  of  the  Company.  This  certification  is  provided  solely  pursuant  to  18  U.S.C.  Section 1350  and  Item 601(b)(32)  of 
Regulation S-K (“Item 601(b)(32)”) promulgated under the Securities Act of 1933, as amended (the “Securities Act”), and the 
Exchange Act. In accordance with clause (ii) of Item 601(b)(32), this certification (A) shall not be deemed “filed” for purposes 
of  Section 18  of  the  Exchange  Act,  or  otherwise  subject  to  the  liability  of  that  section,  and  (B) shall  not  be  deemed  to  be 
incorporated by reference into any filing under the Securities Act or the Exchange Act, except to the extent that the Company 
specifically incorporates it by reference. 

       Date: March 16,  2018 

/s/ JEFFREY A. DUCHEMIN 
Name: Jeffrey A. Duchemin 
Title: Chief Executive Officer 

 
  
  
  
  
  
 
 
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Exhibit 1

Harvard Bioscience, Inc.
Reconciliation of US GAAP Income (Loss) from Continuing Operations to Non-GAAP  
Adjusted Income from Continuing Operations (Unaudited)

US GAAP income (loss) from continuing operations ........................ $ 

723  $  2,355  $ (19,039 ) $  (4,307 ) $ 

Adjustments:

For the Year Ended December 31, 

2013  

2014  

2015  

2016  

2017
(865 )

Amortization of intangible assets ...............................................

 2,590   

 2,578   

 2,819   

 2,722   

 2,442 

Inventory valuation step-up charges on acquisition ...................

Forensic investigation and remediation costs ............................

Impairment charges ...................................................................

Loss on sale of AHN ...................................................................

–    

–    

–    

–    

Transaction costs ........................................................................

5   

1,144   

1,187   

Biostage transaction costs .........................................................

   2,048   

–     

–     

263  

799  

–     

–   

–    

–    

–    

–    

–    

–    

 1,663  

 386

 676  

 1,190  

54   

–     

–  

 95

695 

–   

Restructuring and severance related expenses ..........................

 2,150   

 1,647   

 1,849   

 38   

 492 

Stock-based compensation expense .........................................

 2,599   

 2,156   

 2,755   

 3,497   

 3,500 

Income taxes ..............................................................................

(3,053 )   

(1,250 )   14,035   

(553 )   

(2,521 )

Non-GAAP adjusted income from continuing operations ............... $  7,062 $  8,893 $  4,405 $  4,980 $  4,224

Exhibit 2

Harvard Bioscience, Inc.
Reconciliation of US GAAP Diluted Earnings (Loss) Per Common Share from Continuing Operations to 
Non-GAAP Adjusted Diluted Earnings Per Common Share from Continuing Operations (unaudited)

US GAAP earnings (loss) per diluted share from continuing operations ...  $  0.02   $  0.07   $ 

2013  

2014  

2015  
(0.57 )   $ 

2016  
(0.13 )   $ 

2017
(0.02 ) 

For the Year Ended December 31, 

Adjustments:

Amortization of intangible assets ...............................................

0.08    

0.08    

0.08    

0.08    

0.07 

Inventory valuation step-up charges on acquisition ...................

–     

0.01   

0.02  

–    

–  

Warner

Warner Instruments is a 
developer, manufacturer 

and marketer of specialized 

tools for Electrophysiology 

and Cell Biology research 

including cell chambers, 

perfusion controllers, 

temperature controllers, 

microincubation systems 

and bio-sensing systems.

Forensic investigation and remediation costs ............................

Impairment charges ...................................................................

Loss on sale of AHN ...................................................................

–     

–     

–     

–     

–     

–     

–      

–      

–      

Transaction costs ........................................................................

–      

0.03    

0.04   

Biostage transaction costs .........................................................

0.06  

–     

–     

Restructuring and severance related expenses ..........................

 0.07   

 0.05   

 0.06   

0.02   

0.03   

–      

–     

–      

0.05    

0.01 

Stock-based compensation expense .........................................

0.08    

0.06    

0.08    

0.11    

–   

–   

0.02 

–   

0.01 

0.10 

Income taxes ..............................................................................

 (0.09 )  

 (0.03 )  

 0.42  

 (0.01 )  

 (0.07 )

Non-GAAP adjusted earnings per diluted share from  
  continuing operations ....................................................................  $  0.22  $  0.27  $  0.13  $  0.15  $  0.12

Forward-Looking Statements
This Annual Report contains forward-looking statements.  In some cases, you 
can identify forward-looking statements by terms such as “capitalize,” “increase,” 
“guidance,” “objectives,” “emerging,” “long-term,” “growth,” “potential,” 
“future,” “expects,” “plans,” “achieve,” “could,” “will,” “lead,” “opportunity,” 
“estimate,” “continue,” “strategy,” “intend,” “believe,””see,” “may,” “should,” 
“would,” “seek,” “aim,” “anticipates,” “projects,” “predicts,” “think,” “optimistic,” 
“new,” “goal” and similar expressions.  These statements include, but are not 
limited to,  statements or inferences about our beliefs, plans or objectives, 
management’s confidence or expectations, our business strategy and ability 
to execute such strategy, the outlook for the life sciences industry, and our 
positioning for growth and market demand. 

These statements involve known and unknown risks, uncertainties and other 
factors that may cause our actual results, performance or achievements to 
be materially different from any future results, performance or achievements 
expressed or implied by the forward-looking statements. Forward-looking 
statements include, but are not limited to, statements about management’s 
confidence or expectations, our business strategy, our ability to raise capital 
or borrow funds to consummate acquisitions and the availability of attractive 
acquisition candidates, our expectations regarding future costs of product 
revenues, our anticipated compliance with the covenants contained in our 
credit facility, the adequacy of our financial resources and our plans, objectives, 
expectations and intentions that are not historical facts, plus factors described 
under the heading “Part I, Item 1A. Risk Factors” in our 2017 Annual Report on 
Form 10-K or in our other public filings.

 
 
 
 
 
 
 
 
 
  
 
  
 
 
 
 
 
  
 
  
 
84 October Hill Road
Holliston, Massachusetts 01746
phone 508.893.8066
www.harvardbioscience.com