Imagion Biosystems:
Annual Report 2020

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Plain-text annual report

Imagion Biosystems Limited Annual Report 2020 IBX ANNUA L R EPORT 2020 IBX A NNUAL RE PO RT 20 2 0 Contents 2020 Highlights A Breakthrough in Early Cancer Detection Letter From the Chairman Directors’ Report Remuneration Report (audited) Auditor’s Independence Declaration Consolidated Statement of Profit and Loss and Other Comprehensive Income Consolidated Statement of Financial Position Consolidated Statement of Changes in Equity Consolidated Statement of Cash Flows Notes to the Consolidated Financial Statements Directors’ Declaration Independent Auditor’s Report Shareholder Information Corporate Directory 2 3 5 7 13 22 23 24 25 26 27 55 56 60 63 2020 Highlights MagSenseTM HER2 Breast Cancer Phase I study initiated: • Human Research Ethics Committee (HREC) approval received • Manufacturing of MagSense™ HER2 nanoparticle formulation completed • Study to be undertaken at multiple sites in Australia • Dr Jane Fox – Monash Health - appointed as principal investigator • Study opened for enrolment in December 2020 Collaboration with Siemens Healthineers explores utility of MagSenseTM nanoparticles with conventional MRI Research published from University of Sydney demonstrates utility of Imagion’s nanoparticles with ultra-low field magnetic resonance imaging (ULF MRI) Total of A$12.2 million funds raised (after costs) in 2020, supports continued MagSenseTM HER2 Breast Cancer product development and expanding the product pipeline Entered 2021 in strong cash position Board of Directors strengthened with appointment of Ms Dianne Angus 1 2 IBX ANNUA L R EPORT 2020 IBX A NNUAL RE PO RT 2 02 0 A Breakthrough in Early Cancer Detection A new way to image the body It’s been over 50 years since the last new imaging technology was introduced. X-Ray (Mammography) 1913 Ultrasound 1956 Magnetic Resonance (MRI) 1971 Computed Tomography (CT) 1972 Position Emission Tomography (PET) 1973 We use PrecisionMRX® nanoparticles to find and detect cancer 1. Our MagSense™ nanoparticles use the PrecisionMRX® cores and add a targeting molecule, such as the HER2 antibody currently in development for breast cancer. 2. When injected into the body, these targeted nanoparticles bind to cancerous cells, if present, and produce a detectable magnetic signature. 3. The functional image informs the physician if tumour is present. 4. If no cancer is present, the nanoparticles do not produce a magnetic signature and are harmlessly metabolised by normal body functions. Imagion Biosystems has future plans to develop nanoparticles coated with other antibodies for indicators such as prostate and ovarian cancer. Despite technical advances in these areas, there is a clear unmet need for a new technology that detects cancer with higher specificity and sensitivity without exposing patients to ionizing radiation. In 2019 the U.S. Food and Drug Administration (FDA) Center for Devices and Radiological Health (CDRH), the U.S. agency regulating medical device technologies, designated the MagSense™ System and Test for HER2 breast cancer as a “Breakthrough Device”. “What excites me about MagSense is the potential for a new way to achieve a functional image without radiation. If we are able to show it works clinically it would be a significant breakthrough.” Mike Harsh Non-Executive Director of Imagion and former VP and CTO, GE Healthcare Saving lives through early cancer detection and treatment The global cancer diagnostic market is approximately $100 billion annually, yet every year cancer kills 9 million people because many of these cases are detected too late. There is a clear need for early and better diagnosis. Imagion is on a mission to make cancer more detectable and at an earlier stage where possible. Our first product focuses on improving the staging of HER2 metastatic breast cancer. Future indicators may include primary diagnosis of prostate and ovarian cancer. A small Phase I clinical study for our MagSense™ technology was initiated in Australia in 2020. The study will evaluate the safety of our MagSense™ nanoparticles and provide evidence of feasibility of two imaging methods: PrecisionMRX® iron oxide nanoparticles are core to our business • Precisely made to control for properties important in many biomedical applications. • Super Paramagnetic with high magnetic susceptibility. • Bio-safe, non-toxic. • Non-radioactive. • Commercially available for research use. Use with our proprietary magnetic relaxometry method • Our MagSenseTM instrument uses ultra-sensitive magnetic sensors to detect the tiny bio-safe nanoparticles. • Nanoparticles bound to cancer cells act like a magnetic beacon to identify the presence of a tumour. Use with Magnetic Resonance Imaging (MRI) • Our nanoparticles could offer a safer alternative to the widely used contrast agent gadolinium. • Siemens Healthineers Australia is collaborating with Imagion in our Phase I study to explore the utility of our nanoparticles. 3 4 To learn more about Imagion Biosystems and our MagSense™ technology, please visit https://imagionbiosystems.com/ IBX ANNUA L R EPORT 2020 IBX A NNUAL RE PO RT 2 02 0 Letter From the Chairman Dear Shareholders, It has been a year of strong progress for Imagion Biosystems as we advanced the development of our novel MagSenseTM technology, to initiate our first in-human study for HER2 metastatic breast cancer. We have worked diligently for the past few years to bring us to this point, and are proud to have initiated the study against the backdrop of global uncertainly due the COVID-19 pandemic. Throughout 2020, we have remained steadfast in executing our plan and completing the necessary requirements to get the study underway. This included manufacturing of the MagSense™ HER2 nanoparticles for use in the study, preparing and obtaining Ethics approval (HREC), and of course signing a collaboration agreement with Siemens Healthineers to support our study’s use of Magnetic Resonance Imaging (MRI). I am proud of our team’s achievements to get us to this point. Early in the year we appointed Dr Oliver Steinbach as Vice President Clinical and Regulatory Affairs. Dr Steinbach has been instrumental in leading the execution of the first in-human study. Following our HREC approval we reported that Monash Health was our first clinical site for the study to be led by Dr Jane Fox, the current Director of Breast Services at Monash Health, a highly regarded clinician who has dedicated her career to improving outcomes for patients with breast cancer and who is strongly supportive of the trial. I am also pleased to inform our shareholders that site initiation and training has now begun at a second site as well. The utility of our underlying magnetic nanoparticles in biomedicine continues to expand as evidenced by publications from leading academic organisations. Research from the University of Sydney published earlier in the year highlighted the utility of Imagion’s iron oxide nanoparticles in enabling ultra low-field magnetic resonance imaging (ULF MRI). This finding could lead to a reduced cost and improved accessibility of MRI. Another publication, by researchers at Weill Cornell Medical College, demonstrated the potential utility of our nanoparticles in a HIV-1 therapy, being used to stimulate the body’s immune response by creating a ‘particulate immunogen’. Our ability to raise funds during the year was instrumental in enabling us to continue our efforts to initiate the study unimpeded and has considerably strengthened our balance sheet providing working capital to accelerate key development plans. Additionally, the funds will enable Imagion to expand the product pipeline to other forms of cancers. In April 2020 we completed an oversubscribed Rights Issue and shortfall placement, raising $2.2 million (net of costs). The company raised a further $10.0 million in August and November, in two oversubscribed placements. Each raise was well supported by new and existing sophisticated and institutional investors. Imagion’s balance sheet was also strengthened by non-dilutive funding, with a $2.2 million Research & Development tax rebate received for the 2019 financial year. In May 2020, the company appointed Ms Dianne Angus to its Board of Directors. Ms Angus joined the board as a Non-Executive Director. Ms Angus brings executive management and listed company director experience in the biotechnology, biopharmaceutical, agritech and healthcare industries. Mr Geoff Hollis was appointed as Chief Financial Officer in December this year. He has strengthened our leadership team and is helping to drive the business forward during the next phase of growth. I’d like to thank our tremendous team for the hard work and commitment they have shown, and congratulate them on achieving our goals in 2020. Our path ahead is exciting as we progress our Phase I study, accelerate development plans and expand our product pipeline to include other potential applications of our technology. On behalf of the Board and all Imagion Biosystems employees, I want to thank investors for your continued support. The groundbreaking work we are doing to develop our transformative MagSense™ technology would not be possible without your funding and support. I look forward to updating you during 2021 on our progress. Robert Proulx Executive Chairman Imagion Biosystems Limited 5 6 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Directors' Report The directors present their report, together with the financial statements, on the consolidated entity (referred to  hereafter as the 'consolidated entity') consisting of Imagion Biosystems Limited (referred to hereafter as the 'Company' or  'parent entity' or ‘Imagion’) and the entities it controlled at the end of, or during the year ended 31 December 2020. Directors The following persons were directors of Imagion Biosystems Limited during the whole of the financial year and up to the  date of this report, unless otherwise stated: Mr Robert Proulx Executive Chair / President Robert has been President of Imagion Biosystems since February 2015.  Previous employment  experience includes President / General Manager for Silicon Biosystems and a career in marketing  and sales management with more than 25 years experience in the computer, life science and medical  diagnostics industries.  Some of Robert's other relevant experience include: Vice President Marketing  and Sales for Nanogen Inc.; Senior Vice President of Marketing and Business Development at Gene  Logic; and General Manager, Life Sciences at IGEN International Inc.  Robert holds an M.A. and B.A.  from The State University of New York at Albany and an Executive MBA from the Penn State Smeal  College of Business. Mr Michael Harsh Non‐Executive Director Michael is a co‐founder and Chief Product Officer of Terapede Systems, a digital X‐ray startup that  focuses on developing an ultra‐high resolution medical flat panel X‐ray detector. Prior to co‐founding  Terapede Systems in 2015, Mr. Harsh had a 36‐year long career with General Electric, including  serving as Global Technology Leader – Imaging Technologies at the GE Global Research Center and  culminating with him serving as Vice President and Chief Technology of GE Healthcare. Additionally,  he serves on the boards of directors of Endra Life Sciences (NASDAQ: NDRA), EmOpti and Compute  Health Acquisition Corp as well as being a member the Radiological Society of North America  ("RSNA"), Research & Education Foundation Board of Trustees. He had previously served as a director  for FloDesign Sonics until its acquisition by MilliporeSigma, a division of the Merck Group. Mr. Harsh  is a graduate of Marquette University, where he earned a bachelor’s degree in Electrical Engineering.  He holds numerous U.S. patents in the field of medical imaging and instrumentation. In 2008, Mr.  Harsh was elected to the American Institute for Medical and Biological Engineering College of Fellows  for his significant contributions to the medical and biological engineering field. Mr David Ludvigson Non‐Executive Director David is currently President & CEO at Nanomix, a point‐of‐care diagnostic medical device company.   David is a financial and operating executive with over 35 years of international experience in life  sciences and technology companies including Biogen (formerly IDEC Pharmaceuticals), Matrix  Pharmaceutical, Nanogen, and MIPS Computer Systems.  His experience over 15 years in the  diagnostics arena has led numerous new product efforts from concept to market launch.  David has  conducted many successful strategic transactions including multiple acquisitions, corporate  partnerships, technology and intellectual property licensing agreements, and OEM relationships and  his financing experience includes venture capital, corporate, mezzanine, lease, bank credit line, LBO,  IPO and secondary public sources. 7 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Ms Jovanka Naumoska Non‐Executive Director Jovanka is an Australian‐qualified corporate lawyer with board‐level experience in legal and  regulatory issues pertaining to medical imaging technology.  Jovanka serves Australian scientific  development organisations in an expert capacity on matters relating to corporate law, business  operations, intellectual property development and regulatory compliance.  She formerly held the role  of Company Secretary role for Imagion Biosystems up until 8 December 2020.   Mr Mark Van Asten Non‐Executive Director Mark has over 30 years of experience in the medical diagnostics and life sciences industry.  Much of  this time has been in international business development, strategic planning and introduction of new  technology.  Through Diagnostic Technology, a company he founded, he has been responsible for the  development and introduction of a number of innovative technology platforms and technologies into  mainstream healthcare use, including HPV DNA testing for cervical cancer screening and the  molecular monitoring for both viral infections and cancer treatments.  He holds an Adjunct Senior  Lectures position at the School of Biotechnology and Biomolecular Science, University of NSW where  he has collaborated on a number of research projects related to biosynthetic pathways in bacteria. Ms Dianne Angus Non‐Executive Director, appointed 8 May 2020 Dianne has worked as a senior executive within the biotechnology, agritech and healthcare sectors  for over twenty years and currently serves as non‐executive director with Neuren Pharmaceuticals  Limited (ASX: NEU) and Bionic Vision Technologies Limited. She has built competitive and  differentiated product portfolios, from investment in innovative research and product development  to commercialisation and market entry. Dianne has created many global industry partnerships to  accelerate asset development, financing and provide reputational validation & endorsement. With  eighteen years’ experience in ASX and NASDAQ listed companies, Dianne has expertise in corporate  governance, capital raising and stakeholder engagement within the listed capital market sector.  Dianne holds a B.Sc. (Ed), B.Sc. (Hons), M.(Biotechnology) and is a registered patent & trade mark  attorney. Ms Bronwyn Le Grice Non‐Executive Director, resigned 31 March 2020 Bronwyn has more than 15 years of experience in healthcare and technology markets spanning  venture capital, capital raising and corporate governance for Australian listed companies and non‐ profit organisations.  She is currently Managing Director of ANDHealth, a unique industry‐led non‐ profit organisation focused on strengthening the Australian digital health ecosystem and de‐risking  innovations in digital health.  Prior to founding ANDHealth, Bronwyn was an Investment Director with  leading Australian healthcare venture capital firm BioScience Managers, where she was responsible  for managing significant transactions in the health technology and digital health sectors, resulting in  more than A$65 million of private and public equity raisings.  This included IPOs on the Australian  Securities Exchange and the UK Alternative Investments Market, in addition to participating in deal  origination, due diligence and negotiation for two funds totalling A$96 million under management. Former Director 8 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Company Secretary Mr Geoff Hollis Company Secretary, appointed 8 December 2020 Geoff recently spent two years as CFO / Company Secretary of Victory Offices Limited, a leading  provider of flexible workspace solutions leading them through an IPO on the Australian Stock  Exchange.  Prior to this Geoff spent 8 years as CFO / Company Secretary with Lifestyle Communities  Limited, a fast growing ASX listed provider of residential accommodation for over 50’s.  Geoff  commenced his career with almost 10 years at leading Melbourne based accounting and business  advisory firm, Pitcher Partners.  Geoff is experienced in capital and debt raisings along with ongoing  investor relations function in addition to other CFO and Company Secretarial experience required for  an ASX listed entity on a growth journey.  Geoff is also a member of the Corporate Governance  Institute and Chartered Accountants Australia and New Zealand. Principal activities During the financial year the principal continuing activities of the consolidated entity consisted of: Nanotechnology;  Biotechnology; Cancer Diagnostics; and Medical Imaging using Superparamagnetic Relaxometry. Dividends There were no dividends paid, recommended or declared during the current or previous financial year. Review of operations Revenue and Other Income comprised interest income, and sales of nanoparticles. The Company markets nanoparticles to  customers through its website and expects to continue to do so, though revenue from this activity is not material and not  expected to be material in the near future.   Operating loss of $5,364,007 (2019: $3,432,506 loss) was materially in line with projections and increased from 2019 due  to: the Company increasing research and development expenditure leading up to the first in‐human‐trial being open for  enrolment in December 2020; and increases in share based payment expenses.   In 2020, the Company successfully raised $13,501,480 (before costs) via a rights issue in April 2020 and two placements in  August 2020 and November 2020 to continue to fund the costs to manufacture nanoparticle material, undertake the first‐ in‐human study and continue research projects. Significant changes in state of affairs Bronwyn Le Grice resigned as a non‐executive director on 31 March 2020. The consolidated entity completed a rights issue that raised $2,501,480 (before costs) on 28 April 2020 through a non‐ renounceable rights issue of 250,147,965 shares at $0.01 to existing shareholders, sophisticated and professional  investors. In April 2020, the consolidated entity received $2,195,551 in R&D tax incentives from the Australian Taxation Office. Dianne Angus was appointed as a non‐executive director on 8 May 2020. The consolidated entity completed a placement that raised $5,000,000 (before costs) on 4 August 2020 through the  placement of 111,111,111 shares at $0.045 to existing shareholders, sophisticated and professional investors. The consolidated entity completed a placement that raised $6,000,000 (before costs) on 27 November 2020 through the  placement of 70,588,236 shares at $0.085 to existing shareholders, sophisticated and professional investors. 9 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Matters subsequent to the end of the financial year No other matters or circumstances have arisen since the end of the financial period that has significantly affected or may  significantly affect the operations of the consolidated entity, the results of those operations, or the state of affairs of the  consolidated entity in future financial years. Likely developments and expected results of operations Management expects spending to increase in future periods pending successful results from the Company's first in‐human‐ trial in relation to HER2 breast cancer which was opened for enrolment in December 2020.  If the in‐human‐trial is  successful it is expected spending will increase as the Company moves its focus to a Pivotal Study (Phase III trial).  The  Company also expects to carry out other research and development projects throughout 2021. Environmental regulation The Consolidated Entity is not subject to any significant environment regulation under Australian Commonwealth or State  Law. Information on Directors Name and title: Qualifications: Expertise and experience: Other current directorships: Former directorships (last 3 years): Membership of committees: Interest in shares: Interest in options: Interest in rights: Contractual rights to shares: Name and title: Qualifications: Expertise and experience: Other current directorships: Former directorships (last 3 years): Membership of committees: Interest in shares: Interest in options: Interest in rights: Contractual rights to shares: Mr Robert Proulx (Executive Chair / President) ‐ Master of Arts and Bachelor of Arts, The State University of New York at  Albany; ‐ Executive Master of Business Administration, Penn State Smeal College of  Business. Robert has over 25 years’ experience bringing life science and medical device  products through development and commercialisation and joined the  predecessor company, Senior Scientific as President and Chief Operating  Officer.  None None None 5,987,000 shares 6,458,250 options 5,000,000 performance rights 5,000,000 performance rights are issued under the company's long‐term  incentive plan and will vest into one ordinary share each subject to  achievement of prescribed performance conditions. Mr Michael Harsh (Non‐Executive Director) ‐ Bachelor’s degree in Electrical Engineering, Marquette University With over 36 years’ service to GE, mostly with GE Healthcare on his résumé,  Michael Harsh is extraordinarily fluent in the complex processes of  transforming high‐potential platform technologies into successful medical  diagnostic products.  ENDRA Life Sciences (2016 – present); EmOpti, Inc. (2015 – present);                                                                                              Compute Health Acquisition Corp (2021‐present). FloDesign (2015 ‐ 2019), NociMed (2019‐2020). Audit and Risk Committee, Remuneration and Nomination Committee 260,000 shares 560,000 options Nil Nil 10 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Name and title: Qualifications: Expertise and experience: Other current directorships: Former directorships (last 3 years): Membership of committees: Interest in shares: Interest in options: Interest in rights: Contractual rights to shares: Name and title: Qualifications: Expertise and experience: Other current directorships: Former directorships (last 3 years): Membership of committees: Interest in shares: Interest in options: Interest in rights: Contractual rights to shares: Name and title: Qualifications: Expertise and experience: Other current directorships: Former directorships (last 3 years): Membership of committees: Interest in shares: Interest in options: Interest in rights: Contractual rights to shares: Mr David Ludvigson (Non‐Executive Director) ‐ Bachelor of Science in Accounting, University of Illinois ‐ Masters in Accounting Science, University of Illinois. David is President and CEO of Nanomix, Inc, a mobile diagnostics company.  Previously, David held executive leadership positions with Nanogen, Matrix  Pharmaceutical, IDEC Pharmaceuticals, MIPS Computer Systems, and other  high‐tech companies. He began his career at Price Waterhouse.  China Stem Cells Ltd (2010‐present); Nanōmix Inc. (2014‐present). None Audit and Risk Committee, Disclosure Committee 470,000 shares 695,000 options Nil Nil Ms Jovanka Naumoska (Non‐Executive Director) ‐ Bachelor of Science degree, University of Wollongong; ‐ Bachelor of Law degree and the Graduate Diploma in Legal Practice,  University of Wollongong; ‐Graduate Diploma in Applied Corporate Governance, Governance Institute of  Australia. Jovanka is an Australian‐qualified corporate lawyer with board‐level experience  in legal and regulatory issues pertaining to medical imaging technology.   Jovanka serves Australian scientific development organisations in an expert  capacity on matters relating to corporate law, business operations, intellectual  property development and regulatory compliance. Security Matters Limited;                                                                                       National Accreditation Authority for Translators and Interpreters Limited None Disclosure Committee 260,000 shares 560,000 options Nil Nil Mr Mark Van Asten (Non‐Executive Director) ‐ Bachelor of Science, University of New South Wales As the Managing Director and founder of Diagnostic Technology Pty Ltd, Mark  has been responsible for the development, introduction, and mainstream  healthcare adoption of technologies throughout Australia and Asia. Mark has  also held several director‐level business development positions with US and  Australian diagnostics corporations. None Cimtech Limited Audit and Risk Committee, Remuneration and Nomination Committee 470,000 shares 695,000 options Nil Nil 11 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Name and title: Qualifications: Expertise and experience: Other current directorships: Former directorships (last 3 years): Membership of committees: Interest in shares: Interest in options: Interest in rights: Contractual rights to shares: Ms Dianne Angus (Non‐Executive Director) ‐ Bachelor of Science (Hons), University of Melbourne;  Masters in  Biotechnology, Monash University. Dianne has worked as a senior executive within the biotechnology, agritech and  healthcare sectors for over twenty years.   With eighteen years’ experience in  ASX and NASDAQ listed companies, Dianne has expertise in corporate  governance, capital raising and stakeholder engagement within the listed  capital market sector.  Neuren Pharmaceuticals Limited None Remuneration and Nomination Committee, Disclosure Committee Nil 500,000 options Nil Nil Other current directorships quoted above are current directorships for listed entities only and excludes directorships of all  other types of entities, unless otherwise stated. Former directorships (last 3 years) quoted above are directorships held in the last 3 years for listed entities only and  excludes directorships of all other types of entities, unless otherwise stated. Company secretary Mr Geoff Hollis was appointed as Company Secretary on 8 December 2020, replacing Ms Jovanka Naumoska.  Geoff is a  member of Chartered Accountant Australia and New Zealand, holds a Graduate Diploma in Applied Corporate Governance  from the Governance Institute of Australia and a Bachelor of Commerce from Deakin University. Geoff has 3,000,000 options which are subject to prescribed vesting conditions and 5,000,000 performance rights which  are subject to the achievement of prescribed performance conditions. Meetings of directors The number of meetings of the company's Board of Directors ('the Board') and of each Board committee held during the  year ended 31 December 2020, and the number of meetings attended by each director were: Board Audit & Risk Management  Committee Remuneration & Nomination  Committee No. of  meetings  eligible to  attend 7 7 7 7 7 5 1 Attended 7 7 7 7 7 5 1 No. of  meetings  eligible to  attend ‐ 2 2 2 ‐ ‐ ‐ Attended 2 2 2 ‐ ‐ ‐ ‐ No. of  meetings  eligible to  attend ‐ ‐ 1 1 1 ‐ ‐ Attended ‐ ‐ ‐ ‐ 1 1 1 Mr Robert Proulx Mr Michael Harsh Mr David Ludvigson Ms Jovanka Naumoska Mr Mark Van Asten Ms Dianne Angus(1) Ms Bronwyn Le Grice(2) (1) Appointed 8th May 2020 (2) Resigned 31st March 2020 12                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Remuneration Report (audited) The remuneration report details the key management personnel remuneration arrangements for the consolidated entity,  in accordance with the requirements of the Corporations Act 2001  and its Regulations. Key management personnel are those persons having authority and responsibility for planning, directing and controlling  the activities of the entity, directly or indirectly, including all directors. The remuneration report is set out under the following main headings: • • • • • • principles used to determine the nature and amount of remuneration; details of remuneration; service agreements; share‐based compensation; additional information; and additional disclosures relating to key management personnel. Principles used to determine the nature and amount of remuneration The objective of the consolidated entity's executive reward framework is to ensure reward for performance is competitive  and appropriate for the results delivered. The framework aligns executive reward with the achievement of strategic  objectives and the creation of value for shareholders, and it is considered to conform to the market best practice for the  delivery of reward. The Board of Directors ('the Board') ensures that executive reward satisfies the following key criteria  for good reward governance practices: • • • • competitiveness and reasonableness; acceptability to shareholders; performance linkage / alignment of executive compensation; and transparency. The Board has determined the remuneration arrangements for the directors and executives with the appointment of the  Nomination and Remuneration Committee they will be responsible for determining and reviewing remuneration  arrangements for its directors and executives.  The performance of the consolidated entity depends on the quality of its directors and executives. The remuneration  philosophy is to attract, motivate and retain high performance and high‐quality personnel. The reward framework is designed to align executive reward to shareholders' interests. The Board have considered that it  should seek to enhance shareholders' interests by: • • having economic profit as a core component of plan design; focusing on sustained growth in shareholder wealth, consisting of dividends and growth in share price, and  delivering constant or increasing return on assets as well as focusing the executive on key non‐financial drivers of  value; and attracting and retaining high calibre executives. • Additionally, the reward framework should seek to enhance executives' interests by: • • • rewarding capability and experience; reflecting competitive reward for contribution to growth in shareholder wealth; and providing a clear structure for earning rewards. In accordance with best practice corporate governance, the structure of non‐executive director and executive director  remuneration is separate. 13 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Non‐executive director's remuneration Fees and payments to non‐executive directors reflect the demands and responsibilities of their role. Non‐executive  directors' fees and payments are reviewed annually by the Board. The Board may, from time to time, receive advice from  independent remuneration consultants to ensure non‐executive directors' fees and payments are appropriate and in line  with the market.  The Board recommends the actual payments to directors and shareholders are responsible for ratifying any  recommendations, if appropriate. ASX listing rules require the aggregate non‐executive director’s remuneration be  determined periodically by a general meeting. The aggregate approved remuneration for non‐executive directors is  $250,000. Executive remuneration The consolidated entity aims to reward executives based on their position and responsibility, with a level and mix of  remuneration which has both fixed and variable components. The executive remuneration and reward framework has five components: • • • • • base pay and non‐monetary benefits; short‐term performance incentives; share‐based payments; health care benefits; and other remuneration such as superannuation and long service leave. The combination of these comprises the executive's total remuneration. Fixed remuneration, consisting of base salary and non‐monetary benefits, are reviewed annually by the Remuneration and  Nomination Committee based on individual and business unit performance, the overall performance of the consolidated  entity and comparable market remunerations. Executives may receive their fixed remuneration in the form of cash or other fringe benefits (for example motor vehicle  benefits) where it does not create any additional costs to the consolidated entity and provides additional value to the  executive. The short‐term incentives ('STI') program is designed to align the targets of the business units with the performance  hurdles of executives. STI payments are granted to executives based on specific annual targets and key performance  indicators ('KPI's') being achieved.  No STI payments were proposed or paid during the year to executives. The long‐term incentives ('LTI') include share‐based payments. Shares are awarded to executives over a period of three  years based on long‐term incentive measures. These include increase in shareholders’ value relative to the entire market  and the increase compared to the consolidated entity's direct competitors.  Consolidated entity performance and link to remuneration Remuneration for certain individuals is directly linked to the performance of the consolidated entity. A portion of cash  bonus and incentive payments are dependent on defined earnings per share targets being met. The remaining portion of  the cash bonus and incentive payments are at the discretion of the Nomination and Remuneration Committee. 14 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Details of remuneration Details of the remuneration of key management personnel of the consolidated entity are set out in the following tables. The key management personnel of the consolidated entity include: the Non‐Executive Directors; Executive Director ‐   Robert Proulx; and the Chief Financial Officer ‐ Geoff Hollis and Brian Conn (resigned). 2020 Non‐Executive Directors Michael Harsh David Ludvigson Jovanka Naumoska Mark Van Asten Dianne Angus(1) Bronwyn Le Grice(2) Non‐Executive Directors Robert Proulx Other Key Management Geoff Hollis(3) Brian Conn(4) Short‐term benefits Share‐based payment Cash  salary &  fees $     Cash  bonus $      Non‐ monetary $ Equity‐settled  shares $ Equity‐settled  options $ Total $     20,851      20,851      20,950      20,950      24,726        5,000                     ‐                       ‐                       ‐                       ‐                       ‐                       ‐                            ‐                          ‐                          ‐                          ‐                          ‐                          ‐                        804                        804                        804                        804                        804                           ‐               21,655               21,655               21,754               21,754               25,530                  5,000                            ‐    406,819                     ‐                            ‐                171,225                  29,533             607,577      25,000    178,145                     ‐                       ‐                            ‐                     6,331                    6,318                           ‐                            ‐                          ‐               37,649             178,145  Total   723,292                     ‐                            ‐                177,556                  39,871             940,719  (1) Represents remuneration from 8 May 2020 to 31 December 2020. (2) Represents remuneration from 1 January 2020 to 31 March 2020. (3) Represents remuneration from 1 December 2020 to 31 December 2020. (4) Represents remuneration from 1 January 2020 to 31 July 2020. 15 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 2019 Non‐Executive Directors Michael Harsh David Ludvigson Jovanka Naumoska Mark Van Asten Bronwyn Le Grice John Hazle(1) Non‐Executive Directors Robert Proulx Other Key Management Brian Conn Short‐term benefits Share‐based payment Cash  salary &  fees $     Cash  bonus $      Non‐ monetary $ Equity‐settled  shares $ Equity‐settled  options $ Total $     20,000      20,000      20,000      20,000      25,000      10,000                     ‐                       ‐                       ‐                       ‐                       ‐                       ‐                            ‐                     9,208                          ‐                     9,208                          ‐                     9,208                          ‐                     9,208                          ‐                     4,476                          ‐                     7,800                           ‐                           ‐                           ‐                           ‐                           ‐                           ‐               29,208               29,208               29,208               29,208               29,476               17,800    399,440                     ‐                            ‐              (939,600)                          ‐           (540,160)   209,093                     ‐                            ‐              (183,600)                 16,129               41,622  Total   723,533                     ‐                            ‐           (1,074,092)                 16,129           (334,430) (1) Represents remuneration from 1 January 2019 to 27 June 2019. Due to the reversal of performance rights as a result of the reassessment of probabilities of performance milestone  achievement, the share‐based payments for Robert Proulx and Brian Conn is negative for the year ended 31 December  2019. The proportion of remuneration linked to performance and the fixed proportion are as follows: Non‐Executive Directors Michael Harsh David Ludvigson Jovanka Naumoska Mark Van Asten Dianne Angus Bronwyn Le Grice John Hazle Non‐Executive Directors Robert Proulx Other Key Management Geoff Hollis Brian Conn Fixed Remuneration 2020 2019 At Risk ‐ STI 2020 2019 At Risk ‐ LTI 2020 2019 96% 96% 96% 96% 97%                    ‐    68% 68% 68% 68% 100%              ‐    85% 56%                         ‐                          ‐                          ‐                          ‐                          ‐                          ‐                          ‐                            ‐                            ‐                            ‐                            ‐                            ‐                            ‐                            ‐  4% 4% 4% 4% 3%                          ‐                           ‐  32% 32% 32% 32%                        ‐  15% 44% 67% (74%)                         ‐                            ‐  33% 174% 66%                    ‐    100% 502%                         ‐                          ‐                            ‐                            ‐  34%                          ‐                         ‐  (402%) 16 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Service agreements Remuneration and other terms of employment for key management personnel are formalised in service agreements.  Details of these agreements are as follows: Name: Title: Agreement commenced: Term of agreement: Details: Name: Title: Agreement commenced: Term of agreement: Details: Mr Robert Proulx Executive Chair / President 1 May 2020 3 years, unless extended by mutual agreement ‐Base salary of $US240,000 per annum, to be reviewed annually by the Nomina(cid:415)on and  Remuneration Committee; ‐En(cid:415)tled to up to 16,000,000 Rights and Op(cid:415)ons under the Equity Incen(cid:415)ve Plan (subject  to certain milestones being met); ‐12 months termina(cid:415)on no(cid:415)ce by the Company. Mr Geoff Hollis Chief Financial Officer / Company Secretary 1 December 2020 Ongoing ‐Base salary of $AUD300,000 per annum, to be reviewed annually by the Nomina(cid:415)on  and Remuneration Committee; ‐En(cid:415)tled to up to 8,000,000 Rights and Op(cid:415)ons under the Equity Incen(cid:415)ve Plan (subject  to certain milestones being met); ‐3 months termina(cid:415)on no(cid:415)ce by either party. Key management personnel have no entitlement to termination payments in the event of removal for misconduct. Share‐based compensation Issue of shares On 29 April 2020, 150,000 rights were converted into ordinary shares to a former director. On 23 June 2020, 200,000 rights were converted into ordinary shares to directors. On 28 August 2020, 2,000,000 options were exercised and converted into ordinary shares to a former key management  personnel. On 10 September 2020, 2,500,000 rights were converted into ordinary shares to the executive director. On 22 October 2020, 2,500,000 rights were converted into ordinary shares to the executive director. On 26 November 2020, 100,000 options were exercised and converted into ordinary shares to a former key management  personnel. 17 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Options The terms and conditions of each grant of options over ordinary shares affecting remuneration of directors and other key  management personnel in this financial year or future reporting years are as follows: Name Number of options  granted Grant date                     2,000,000  Robert Proulx                     2,000,000  Robert Proulx                     2,000,000  Robert Proulx                        250,000  Michael Harsh                        250,000  Michael Harsh                        250,000  David Ludvigson                        250,000  David Ludvigson Jovanka Naumoska                        250,000  Jovanka Naumoska                        250,000  Mark Van Asten                        250,000                         250,000  Mark Van Asten                        250,000  Dianne Angus                        250,000  Dianne Angus                     1,000,000  Geoff Hollis                     1,000,000  Geoff Hollis                     1,000,000  Geoff Hollis Options granted carry no dividend or voting rights. 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 9‐Dec‐20 9‐Dec‐20 9‐Dec‐20 Vesting and  exercisable  date 1‐May‐21 1‐May‐22 1‐May‐23 1‐May‐21 1‐May‐22 1‐May‐21 1‐May‐22 1‐May‐21 1‐May‐22 1‐May‐21 1‐May‐22 1‐May‐21 1‐May‐22 30‐Nov‐21 30‐Nov‐22 30‐Nov‐23 Expiry date 1‐May‐26 1‐May‐27 1‐May‐28 1‐May‐26 1‐May‐27 1‐May‐26 1‐May‐27 1‐May‐26 1‐May‐27 1‐May‐26 1‐May‐27 1‐May‐26 1‐May‐27 30‐Nov‐26 30‐Nov‐27 30‐Nov‐28 Exercise price  $                 0.028                  0.028                  0.028                  0.028                  0.028                  0.028                  0.028                  0.028                  0.028                  0.028                  0.028                  0.028                  0.028                  0.140                  0.140                  0.140  Fair value per  option at grant  date $                   0.010                    0.014                    0.016                    0.010                    0.014                    0.010                    0.014                    0.010                    0.014                    0.010                    0.014                    0.010                    0.014                    0.045                    0.064                    0.077  Performance rights The terms and conditions of each grant of performance rights over ordinary shares affecting remuneration of directors  and other key management personnel in this financial year or future reporting are as follows: Fair value per  right at grant  date $                   0.028                    0.063  Exercise price  $                        ‐                           ‐    Name Number of  rights  granted Grant date Expiry date Robert Proulx(1) Geoff Hollis (1) Note: 5,000,000 performance rights were converted into ordinary shares during the financial year upon achievement  of performance milestones. Performance rights granted carry no dividend or voting rights.   10,000,000      5,000,000  30‐Apr‐23 30‐Nov‐23 6‐Aug‐20 9‐Dec‐20 Additional information The historical earnings of the Consolidated Entity are summarised below: Revenue Net loss before tax Net loss after tax 2020 $       2,696,964        5,364,007        5,364,007  2019 $         2,490,000          3,432,506          3,432,506  2018 $            371,489          8,340,013          8,340,013  2017 $            339,057          7,794,602          7,794,602  18 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 The factors that are considered to affect total shareholders return (‘TSR’) are summarised below: Share price at the start of the financial year ($) Share price at the end of the financial year ($) 2020               0.025                0.145  2019                 0.030                  0.025  2018                 0.110                  0.030  2017                 0.200                  0.110  Basic earnings per share (cents per share) Diluted earnings per share (cents per share)              (0.007)              (0.007)               (0.010)               (0.010)               (0.038)               (0.038)               (0.051)               (0.051) Additional disclosures relating to key management personnel Shareholding The number of shares in the company held during the financial year by each director and other members of key  management personnel of the consolidated entity, including their personally related parties, is set out below: Name Robert Proulx Michael Harsh David Ludvigson Jovanka Naumoska Mark Van Asten Dianne Angus Geoff Hollis Total Balance at  start of year         705,000          150,000          300,000          150,000          300,000                     ‐                       ‐        1,605,000  Received  Additions remuneration          5,000,000                282,000                  60,000                 50,000                 50,000                120,000                  60,000                 50,000                 50,000                120,000                            ‐                          ‐                            ‐                          ‐           5,200,000                642,000  Disposals                        ‐                           ‐                           ‐                           ‐                           ‐                           ‐                           ‐                           ‐    Balance at the  end of the year           5,987,000                260,000                470,000                260,000                470,000                           ‐                           ‐            7,447,000  Option holding The number of options over ordinary shares in the company held during the financial year by each director and other  members of key management personnel of the consolidated entity, including their personally related parties, is set out  below:  Name Robert Proulx Michael Harsh David Ludvigson Jovanka Naumoska Mark Van Asten Dianne Angus Geoff Hollis Total Balance at  start of year         176,250                     ‐              75,000                     ‐              75,000                     ‐                       ‐            326,250  Granted          6,000,000               500,000               500,000               500,000               500,000               500,000           3,000,000         11,500,000  Exercised                           ‐                            ‐                            ‐                            ‐                            ‐                            ‐                            ‐                            ‐  Expired /  forfeited /  other            282,000               60,000             120,000               60,000             120,000                         ‐                           ‐               642,000  Balance at the  end of the year           6,458,250                560,000                695,000                560,000                695,000                500,000            3,000,000          12,468,250  19 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Performance rights holding The number of performance shares in the company held during the financial year by each director and other members of  key management personnel of the consolidated entity, including their personally related parties, is set out below: Name Robert Proulx Michael Harsh David Ludvigson Jovanka Naumoska Mark Van Asten Dianne Angus Geoff Hollis Total Balance at  start of year     8,700,000            50,000            50,000            50,000            50,000                     ‐                       ‐        8,900,000  Granted Vested        10,000,000           (5,000,000)                         ‐                (50,000)                         ‐                (50,000)                         ‐                (50,000)                         ‐                (50,000)                           ‐                          ‐                            ‐           5,000,000         15,000,000           (5,200,000) Expired /  forfeited /  other       (8,700,000)                        ‐                           ‐                           ‐                           ‐                           ‐                           ‐          (8,700,000) Balance at the  end of the year           5,000,000                           ‐                           ‐                           ‐                           ‐                           ‐            5,000,000          10,000,000  This concludes the remuneration report, which has been audited. Shares under option Unissued ordinary shares of Imagion Biosystems Limited under option at the date of this report are as follows: Grant date 6‐Jun‐18 24‐Jun‐19 22‐Oct‐19 22‐Oct‐19 22‐Oct‐19 26‐Nov‐19 28‐Apr‐20 6‐Aug‐20 6‐Aug‐20 6‐Aug‐20 29‐Sep‐20 9‐Dec‐20 9‐Dec‐20 9‐Dec‐20 10‐Feb‐21 Expiry date 20‐Jun‐21 24‐Jun‐24 20‐Sep‐24 22‐Aug‐24 7‐Oct‐24 26‐Nov‐21 28‐Apr‐23 1‐May‐26 1‐May‐27 1‐May‐28 30‐Sep‐25‐31‐Aug‐28 30‐Nov‐26 30‐Nov‐27 30‐Nov‐28 28‐Feb‐28‐31‐Jan‐29 Exercise  price Number  under option $0.2000       3,000,000  $0.0280       2,150,000  $0.0600           100,000  $0.0600           300,000  $0.0600           200,000  $0.0500     87,000,705  $0.0300   239,739,933  $0.0280       3,250,000  $0.0280       3,250,000  $0.0280       2,000,000  $0.0909     10,150,000  $0.1400       1,000,000  $0.1400       1,000,000  $0.1400       1,000,000  $0.1750       2,500,000    356,640,638  Shares issued on the exercise of options The following ordinary shares of Imagion Biosystems Limited were issued during the year ended 31 December 2020 and  up to the date of this report on the exercise of options granted: Date options granted 18‐Aug‐20 28‐Aug‐20 20‐Oct‐20 26‐Nov‐20 15‐Feb‐21 11‐Aug‐20 to 23‐Feb‐21(1) 4‐Sep‐20 to 23‐Feb‐21(2) Exercise price $0.0600 $0.0280 $0.0600 $0.0600 $0.0194 ‐ $0.0593 $0.0300 $0.0500 Number of shares issued      21,600,000          2,000,000          2,370,000       10,730,000          2,986,604       28,908,032          9,705,690       78,300,326  (1) 45 separate conversions of listed options occurred between the dates as per above (2) 26 separate conversions of listed options occurred between the dates as per above 20 Imagion Biosystems Limited Directors' Report For the year ended 31 December 2020 Indemnity and insurance of officers The company has indemnified the directors and executives of the company for costs incurred, in their capacity as a  director or executive, for which they may be held personally liable, except where there is a lack of good faith. During the financial year, the company paid a premium in respect of a contract to insure the directors and executives of  the company against a liability to the extent permitted by the Corporations Act 2001. The contract of insurance prohibits  disclosure of the nature of the liability and the amount of the premium. Proceedings on behalf of the company No person has applied to the Court under Section 237 of the Corporations Act 2001 for leave to bring proceedings on  behalf of the company, or to intervene in any proceedings to which the company is a party for the purpose of taking  responsibility on behalf of the company for all or part of those proceedings. Non‐audit services Non‐audit services provided during the financial year by the auditor included $4,700 for advice in relation to adopting  AASB 16 and option valuation services.  The Directors are satisfied that the provision of these non‐audit services is  compatible with the general standard of independence for auditors imposed by the Corporations Act 2001.  The nature  and scope of these non‐audit services mean that auditor independence was not compromised. Rounding of amounts The company is of a kind referred to in Corporations Instrument 2016/191, issued by the Australian Securities and  Investments Commission, relating to 'rounding‐off'. Amounts in this report have been rounded off in accordance with that  Corporations Instrument to the nearest thousand dollars, or in certain cases, the nearest dollar. Auditor's independence declaration A copy of the auditor's independence declaration as required under section 307C of the Corporations Act 2001 is set out  immediately after this directors' report. On behalf of the directors Robert Proulx Director 25 February 2021 21 AUDITOR’S INDEPENDENCE DECLARATION As lead auditor for the audit of the financial report of Imagion Biosystems Limited and its subsidiaries for the year ended 31 December 2020, I declare that, to the best of my knowledge and belief, there have been no contraventions of: (i) the auditor independence requirements of the Corporations Act 2001 in relation to the audit; and (ii) any applicable code of professional conduct in relation to the audit. RSM AUSTRALIA PARTNERS R B MIANO Partner Dated: 25 February 2021 Melbourne, Victoria 22 Imagion Biosystems Limited Consolidated Statement of Profit and Loss and Other Comprehensive Income For the year ended 31 December 2020 Revenue Revenue and other income Research & development tax incentives Operating Expenses  Research & development expenses Employment expenses Professional fees General expenses Share based payments expense Depreciation expense Foreign exchange gain/(loss) Finance costs Note 4 5 5 2020 $   501,413 2,195,551 2,696,964 (2,860,772) (2,424,170) (1,161,389) (749,786) (399,145) (360,574) (61,283) (43,852) (8,060,971) 2019 $   432,714 2,057,286 2,490,000 (2,269,006) (2,757,564) (784,023) (868,684) 940,754 (141,988) (32,837) (9,158) (5,922,506) Loss before income tax expense (5,364,007) (3,432,506) Income tax expense (benefit) Loss after Income Tax Expense Other comprehensive income ‐   ‐   (5,364,007) (3,432,506) Items that may be reclassified subsequently to profit or loss Foreign currency translation reserve 15 (92,235) (70,284) Income tax relating to these items ‐   ‐   Other comprehensive income/(loss), net of tax (92,235) (70,284) Total comprehensive Income (loss) for the year Attributable to the  Owners of Imagion Biosystems Limited (5,456,242) (3,502,790) Basic earnings (loss) per share Diluted earnings (loss) per share Cents                  (0.007)                  (0.007) Cents                   (0.010)                   (0.010) 23 23 These financial statements should be read in conjunction with the accompanying notes. 23   Imagion Biosystems Limited Consolidated Statement of Financial Position As at 31 December 2020 Current Assets Cash and cash equivalents Trade and other receivables Other current assets Total Current Assets Non‐Current Assets Property, plant and equipment Right‐of‐use assets Total Non‐Current Assets Total Assets Current Liabilities Trade and other payables Lease liabilities Employee benefits Other liabilities Total Current Liabilities Non‐Current Liabilities Lease liabilities (NCA) Employee benefits Total Non‐Current Liabilities Total Liabilities Net Assets Equity Issued capital Reserves Accumulated losses Total Equity Note 6 7 8 9 10 11 12 13 11 12 14 15 16 2020 $   13,200,547  ‐   233,440  13,433,987  160,432  524,585  685,017  2019 $  3,401,713  71  171,112  3,572,896  434,150  865,051  1,299,201             14,119,004              4,872,097  402,090  358,230  109,095  31,438  900,853  302,748  1,536  304,284  885,979  261,760  101,832  33,990  1,283,561  615,019  ‐  615,019  1,205,137  1,898,580  12,913,867  2,973,517  51,322,126  1,601,289  (40,009,548) 12,913,867  36,904,580  714,478  (34,645,541) 2,973,517  These financial statements should be read in conjunction with the accompanying notes. 24 Imagion Biosystems Limited Consolidated Statement of Changes in Equity For the year ended 31 December 2020 Issued Capital $   Reserves $   Accumulated Losses $   Total Equity $   Balance as at 1 January 2019 33,182,325 1,899,938 (31,213,035) 3,869,228  Loss after income tax Other comprehensive income/(loss) after tax Total comprehensive income/(loss) ‐ ‐ ‐ ‐ (70,284) (3,432,506) ‐    (3,432,506) (70,284) (70,284) (3,432,506) (3,502,790) Transactions with owners in their capacity as owners Contributions of equity Costs of contributions of equity Transfer from reserves Share based payments Balance as at 31 December 2019 3,848,272  (287,033) 161,016  ‐ 36,904,580  Issued Capital $   ‐ ‐ (161,016) (954,160) 714,478  Reserves $   ‐ ‐ ‐ ‐ (34,645,541) Accumulated Losses $   3,848,272  (287,033) ‐ (954,160) 2,973,517  Total Equity $   Balance as at 1 January 2020 36,904,580 714,478 (34,645,541) 2,973,517  Loss after income tax Other comprehensive income/(loss) after tax Total comprehensive income/(loss) ‐ ‐ ‐ ‐ (92,235) (5,364,007) ‐ (5,364,007) (92,235) (92,235) (5,364,007) (5,456,242) Transactions with owners in their capacity as owners Contributions of equity Costs of contributions of equity Transfer from reserves Share based payments Balance as at 31 December 2020 16,157,593  (1,901,922) 161,875 ‐ 51,322,126  ‐ ‐ (161,875) 1,140,921 1,601,289  ‐ ‐ ‐ ‐ (40,009,548) 16,157,593  (1,901,922) ‐    1,140,921 12,913,867  These financial statements should be read in conjunction with the accompanying notes. 25                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   Imagion Biosystems Limited Consolidated Statement of Cash Flows For the year ended 31 December 2020 Note Cash Flows from Operating Activities Receipts from customers (inc of sales and other taxes) Payments to suppliers and employees (inc of sales and other taxes) Interest received  Interest and other finance costs paid  Government grants and tax incentives Net cash outflow from operating activities 22 Cash Flows from Investing Activities Payment for property, plant and equipment Net cash outflow from investing activities Cash Flows from Financing Activities Proceeds from the issue of shares Share issue costs Proceeds from the exercise of options Proceeds from financing arrangements Loan from US Government authority Lease repayments Net cash inflow from financing activities  2020 $   319,125 (7,102,542) 1,132 (36,356) 2,195,551 (4,623,090) 2019 $   558,844 (6,815,862) 16,556 (3,501) 2,061,918 (4,182,045) (7,860) (7,860) (12,353) (12,353) 13,501,480 (1,340,077) 2,606,144 ‐   233,815 (480,624) 14,520,738 3,369,266 (13,305) 5,148 84,770 ‐   (120,165) 3,325,714 Net increase (decrease) in cash and cash equivalents 9,889,788 (868,684) Cash and cash equivalents at start of year Effects of exchange rate changes on cash and cash equivalents 3,401,713 (90,954) 4,367,097 (96,700) Cash and cash equivalents at end of year 6 13,200,547 3,401,713 These financial statements should be read in conjunction with the accompanying notes. 26                                     Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies The principal accounting policies adopted in the preparation of the financial statements are set out below. These policies have been consistently applied to all the years presented, unless otherwise stated. The financial statements of Imagion Biosystems Limited & Controlled Entities (the "consolidated entity") for 31 December 2020 were authorised for issue by the Directors on 25 February 2021. Basis of Preparation  a)  These general purpose financial statements have been prepared in accordance with Australian Accounting  Standards and Interpretations issued by the Australian Accounting Standards Board ('AASB') and the  Corporations Act 2001 , as appropriate for for‐profit oriented entities. These financial statements also comply  with International Financial Reporting Standards as issued by the International Accounting Standards Board  ('IASB'). Historical cost convention The financial statements have been prepared under the historical cost convention, except for, where applicable,  the revaluation of available‐for‐sale financial assets, financial assets and liabilities at fair value through profit or  loss, investment properties, certain classes of property, plant and equipment and derivative financial  instruments. Critical accounting estimates The preparation of the financial statements requires the use of certain critical accounting estimates. It also  requires management to exercise its judgement in the process of applying the consolidated entity's accounting  policies. The areas involving a higher degree of judgement or complexity, or areas where assumptions and  estimates are significant to the financial statements, are disclosed in note 2. Parent entity information In accordance with the Corporations Act 2001 , these financial statements present the results of the  consolidated entity only.  Supplementary information about the parent entity is disclosed in note 20. Principles of consolidation The consolidated financial statements incorporate the assets and liabilities of all subsidiaries of Imagion  Biosystems Limited as at 31 December 2020 and the results of all subsidiaries for the year then ended. Imagion  Biosystems Limited and its subsidiaries together are referred to in these financial statements as the  'consolidated  entity'. Subsidiaries are all those entities over which the consolidated entity has control. The consolidated entity controls an entity when the consolidated entity is exposed to, or has rights to, variable returns from its involvement with the entity and has the ability to affect those returns through its power to direct the activities of the entity. Subsidiaries are fully consolidated from the date on which control is transferred to the consolidated entity. They are de‐consolidated from the date that control ceases. Intercompany transactions, balances and unrealised gains on transactions between entities in the consolidated entity are eliminated. Unrealised losses are also eliminated unless the transaction provides evidence of the impairment of the asset transferred. Accounting policies of subsidiaries have been changed where necessary to ensure consistency with the policies adopted by the consolidated entity. 27 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) The acquisition of subsidiaries is accounted for using the acquisition method of accounting. A change in ownership interest, without the loss of control, is accounted for as an equity transaction, where the difference between the consideration transferred and the book value of the share of the non‐controlling interest acquired is recognised directly in equity attributable to the parent. Non‐controlling interest in the results and equity of subsidiaries are shown separately in the statement of profit or loss and other comprehensive income, statement of financial position and statement of changes in equity of the consolidated entity. Losses incurred by the consolidated entity are attributed to the non‐controlling interest in full, even if that results in a deficit balance. Where the consolidated entity loses control over a subsidiary, it derecognises the assets including goodwill, liabilities and non‐controlling interest in the subsidiary together with any cumulative translation differences recognised in equity. The consolidated entity recognises the fair value of the consideration received and the fair value of any investment retained together with any gain or loss in profit or loss.  Comparatives Comparative figures for the prior year have been re‐classified where appropriate to align with current year  disclosures. Going Concern b) The financial statements have been prepared on the going concern basis, which contemplates continuity of  normal business activities and the realisation of assets and discharge of liabilities in the normal course of  business. As disclosed in the financial statements, the consolidated entity incurred a loss of $5,364,007 (2019:  $3,432,506), and had net cash outflows from operating activities of $4,623,090 (2019: $4,182,045) for the year  ended 31 December 2020.  The consolidated entity is still in the product development phase recording minimal  sales revenue, consequently it is dependent on external funding to cover ongoing product development and has  forecast losses for the next financial year.   Despite this financial position, the Directors believe that there are reasonable grounds to believe that the  consolidated entity will be able to continue as a going concern after considering the following factors: • • • • The consolidated entity successfully raised $14.8 million (net of costs) during 2020 from a combination of  rights issues, placements and exercises of options; The consolidated entity is expecting to receive further material funds upon the exercise of listed options in  2021; The Directors are confident that the consolidated entity has sufficient funds to meet its objectives in 2021;  The consolidated entity has historically received some cost relief through the receipt of research &  development income tax incentives and the directors expect this to continue. 28 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) Foreign currency translation c) The financial statements are presented in Australian dollars, which is Imagion Biosystems Limited's functional  and presentation currency. Foreign currency transactions Foreign currency transactions are translated into Australian dollars using the exchange rates prevailing at the dates of the transactions. Foreign exchange gains and losses resulting from the settlement of such transactions and from the translation at financial year‐end exchange rates of monetary assets and liabilities denominated in foreign currencies are recognised in profit or loss. Foreign operations The assets and liabilities of foreign operations are translated into Australian dollars using the exchange rates at  the reporting date. The revenues and expenses of foreign operations are translated into Australian dollars using  the average exchange rates, which approximate the rates at the dates of the transactions, for the period. All  resulting foreign exchange differences are recognised in other comprehensive income through the foreign  currency reserve in equity.  The foreign currency reserve is recognised in profit or loss when the foreign operation or net investment is  disposed of. d) Revenue recognition Revenue from contracts with customers Revenue is recognised at an amount that reflects the consideration to which the consolidated entity is expected  to be entitled in exchange for transferring goods or services to a customer. For each contract with a customer,  the consolidated entity: identifies the contract with a customer; identifies the performance obligations in the  contract; determines the transaction price which takes into account estimates of variable consideration and the  time value of money; allocates the transaction price to the separate performance obligations on the basis of the  relative stand‐alone selling price of each distinct good or service to be delivered; and recognises revenue when  or as each performance obligation is satisfied in a manner that depicts the transfer to the customer of the goods  or services promised. Variable consideration within the transaction price, if any, reflects concessions provided to the customer such as  discounts, rebates and refunds, any potential bonuses receivable from the customer and any other contingent  events. Such estimates are determined using either the 'expected value' or 'most likely amount' method. The  measurement of variable consideration is subject to a constraining principle whereby revenue will only be  recognised to the extent that it is highly probable that a significant reversal in the amount of cumulative  revenue recognised will not occur. The measurement constraint continues until the uncertainty associated with  the variable consideration is subsequently resolved. Amounts received that are subject to the constraining  principle are recognised as a refund liability. Sale of goods Revenue from the sale of goods is recognised at the point in time when the customer obtains control of the  goods, which is generally at the time of delivery. 29 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) Interest Interest revenue is recognised as interest accrues using the effective interest method. This is a method of calculating the amortised cost of a financial asset and allocating the interest income over the relevant period using the effective interest rate, which is the rate that exactly discounts estimated future cash receipts through the expected life of the financial asset to the net carrying amount of the financial asset. Other revenue Other revenue is recognised when it is received or when the right to receive payment is established. Income tax e) The income tax expense or benefit for the period is the tax payable on that period's taxable income based on the applicable income tax rate for each jurisdiction, adjusted by the changes in deferred tax assets and liabilities attributable to temporary differences, unused tax losses and the adjustment recognised for prior periods, where applicable. Deferred tax assets and liabilities are recognised for temporary differences at the tax rates expected to be  applied when the assets are recovered, or liabilities are settled, based on those tax rates that are enacted or  substantively enacted, except for: • • When the deferred income tax asset or liability arises from the initial recognition of goodwill or an asset or  liability in a transaction that is not a business combination and that, at the time of the transaction, affects  neither the accounting nor taxable profits; or When the taxable temporary difference is associated with interests in subsidiaries, associates or joint  ventures, and the timing of the reversal can be controlled, and it is probable that the temporary difference  will not reverse in the foreseeable future. Deferred tax assets are recognised for deductible temporary differences and unused tax losses only if it is  probable that future taxable amounts will be available to utilise those temporary differences and losses. The carrying amount of recognised and unrecognised deferred tax assets are reviewed at each reporting date. Deferred tax assets recognised are reduced to the extent that it is no longer probable that future taxable profits will be available for the carrying amount to be recovered. Previously unrecognised deferred tax assets are recognised to the extent that it is probable that there are future taxable profits available to recover the asset. Deferred tax assets and liabilities are offset only where there is a legally enforceable right to offset current tax  assets against current tax liabilities and deferred tax assets against deferred tax liabilities; and they relate to the  same taxable authority on either the same taxable entity or different taxable entities which intend to settle  simultaneously. Current and non‐current classification f) Assets and liabilities are presented in the statement of financial position based on current and non‐current  classification. An asset is classified as current when: it is either expected to be realised or intended to be sold or consumed in  the consolidated entity's normal operating cycle; it is held primarily for the purpose of trading; it is expected to  be realised within 12 months after the reporting period; or the asset is cash or cash equivalent unless restricted  from being exchanged or used to settle a liability for at least 12 months after the reporting period. All other  assets are classified as non‐current. 30 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) A liability is classified as current when: it is either expected to be settled in the consolidated entity's normal operating cycle; it is held primarily for the purpose of trading; it is due to be settled within 12 months after the reporting period; or there is no unconditional right to defer the settlement of the liability for at least 12 months after the reporting period. All other liabilities are classified as non‐current. Deferred tax assets and liabilities are always classified as non‐current. Cash and cash equivalents g) Cash and cash equivalents includes cash on hand, deposits held at call with financial institutions, other short‐ term, highly liquid investments with original maturities of three months or less that are readily convertible to  known amounts of cash and which are subject to an insignificant risk of changes in value. For the statement of  cash flows presentation purposes, cash and cash equivalents also includes bank overdrafts, which are shown  within borrowings in current liabilities on the statement of financial position. Trade and other receivables h) Trade receivables are initially recognised at fair value and subsequently measured at amortised cost using the  effective interest method, less any allowance for expected credit losses. Trade receivables are generally due for  settlement within 30 days. The consolidated entity has applied the simplified approach to measuring expected credit losses, which uses a  lifetime expected loss allowance. To measure the expected credit losses, trade receivables have been grouped  based on days overdue. Other receivables are recognised at amortised cost, less any allowance for expected credit losses. Investments and other financial assets i) Investments and other financial assets are initially measured at fair value. Transaction costs are included as part  of the initial measurement, except for financial assets at fair value through profit or loss. Such assets are  subsequently measured at either amortised cost or fair value depending on their classification. Classification is  determined based on both the business model within which such assets are held and the contractual cash flow  characteristics of the financial asset unless, an accounting mismatch is being avoided. Financial assets are derecognised when the rights to receive cash flows have expired or have been transferred  and the consolidated entity has transferred substantially all the risks and rewards of ownership. When there is  no reasonable expectation of recovering part or all a financial asset, it's carrying value is written off. Financial assets at fair value through profit or loss Financial assets not measured at amortised cost or at fair value through other comprehensive income are  classified as financial assets at fair value through profit or loss. Typically, such financial assets will be either: (i)  held for trading, where they are acquired for the purpose of selling in the short‐term with an intention of  making a profit, or a derivative; or (ii) designated as such upon initial recognition where permitted. Fair value  movements are recognised in profit or loss. Financial assets at fair value through other comprehensive income Financial assets at fair value through other comprehensive income include equity investments which the  consolidated entity intends to hold for the foreseeable future and has irrevocably elected to classify them as  such upon initial recognition. 31 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) Impairment of financial assets The consolidated entity recognises a loss allowance for expected credit losses on financial assets which are  either measured at amortised cost or fair value through other comprehensive income. The measurement of the  loss allowance depends upon the consolidated entity's assessment at the end of each reporting period as to  whether the financial instrument's credit risk has increased significantly since initial recognition, based on  reasonable and supportable information that is available, without undue cost or effort to obtain. Where there has not been a significant increase in exposure to credit risk since initial recognition, a 12‐month  expected credit loss allowance is estimated. This represents a portion of the asset's lifetime expected credit  losses that is attributable to a default event that is possible within the next 12 months. Where a financial asset  has become credit impaired or where it is determined that credit risk has increased significantly, the loss  allowance is based on the asset's lifetime expected credit losses. The amount of expected credit loss recognised  is measured on the basis of the probability weighted present value of anticipated cash shortfalls over the life of  the instrument discounted at the original effective interest rate. For financial assets measured at fair value through other comprehensive income, the loss allowance is  recognised within other comprehensive income. In all other cases, the loss allowance is recognised in profit or  loss. Property, plant and equipment j) Plant and equipment is stated at historical cost less accumulated depreciation and impairment. Historical cost  includes expenditure that is directly attributable to the acquisition of the items. Depreciation is calculated using straight‐line and diminishing value methods to write off the net cost of each  item of property, plant and equipment (excluding land) over their expected useful lives as follows: Plant and equipment 3‐10 years The residual values, useful lives and depreciation methods are reviewed, and adjusted if appropriate, at each  reporting date. An item of property, plant and equipment is derecognised upon disposal or when there is no future economic  benefit to the consolidated entity. Gains and losses between the carrying amount and the disposal proceeds are  taken to profit or loss. Any revaluation surplus reserve relating to the item disposed of is transferred directly to  retained profits. Right‐of‐use assets k) A right‐of‐use asset is recognised at the commencement date of a lease. The right‐of‐use asset is measured at  cost, which comprises the initial amount of the lease liability, adjusted for, as applicable, any lease payments  made at or before the commencement date net of any lease incentives received, any initial direct costs incurred,  and, except where included in the cost of inventories, an estimate of costs expected to be incurred for  dismantling and removing the underlying asset, and restoring the site or asset. Right‐of‐use assets are depreciated on a straight‐line basis over the unexpired period of the lease or the  estimated useful life of the asset, whichever is the shorter. Where the consolidated entity expects to obtain  ownership of the leased asset at the end of the lease term, the depreciation is over its estimated useful life.  Right‐of use assets are subject to impairment or adjusted for any remeasurement of lease liabilities. 32 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) The consolidated entity has elected not to recognise a right‐of‐use asset and corresponding lease liability for  short‐term leases with terms of 12 months or less and leases of low‐value assets. Lease payments on these  assets are expensed to profit or loss as incurred. Research and development l) Research costs for the development of intellectual property are expenses in the period in which they are  incurred. Development costs are capitalised when it is probable that the project will be a success considering its  commercial and technical feasibility; the consolidated entity is able to use or sell the asset; the consolidated  entity has sufficient resources; and intent to complete the development and its costs can be measured reliably.  Following the initial recognition of the development expenditure, the cost model is applied requiring the asset  to be carried at cost less any accumulated amortisation and accumulated impairment losses. Any expenditure is  capitalised and is amortised on a straight‐line basis over the period of expected benefits from the related  project.  Trade and other payables m) These amounts represent liabilities for goods and services provided to the consolidated entity prior to the end of  the financial year and which are unpaid. Due to their short‐term nature they are measured at amortised cost  and are not discounted. The amounts are unsecured and are usually paid within 30 days of recognition.  Borrowings n) Loans and borrowings are initially recognised at the fair value of the consideration received, net of transaction  costs. They are subsequently measured at amortised cost using the effective interest method. Lease liabilities o) A lease liability is recognised at the commencement date of a lease. The lease liability is initially recognised at  the present value of the lease payments to be made over the term of the lease, discounted using the interest  rate implicit in the lease or, if that rate cannot be readily determined, the consolidated entity's incremental  borrowing rate. Lease payments comprise of fixed payments less any lease incentives receivable, variable lease  payments that depend on an index or a rate, amounts expected to be paid under residual value guarantees,  exercise price of a purchase option when the exercise of the option is reasonably certain to occur, and any  anticipated termination penalties. The variable lease payments that do not depend on an index or a rate are  expensed in the period in which they are incurred.  Lease liabilities are measured at amortised cost using the effective interest method. The carrying amounts are  remeasured if there is a change in the following: future lease payments arising from a change in an index or a  rate used; residual guarantee; lease term; certainty of a purchase option and termination penalties. When a  lease liability is remeasured, an adjustment is made to the corresponding right‐of use asset, or to profit or loss if  the carrying amount of the right‐of‐use asset is fully written down. Finance costs p) Finance costs attributable to qualifying assets are capitalised as part of the asset. All other finance costs are  expensed in the period in which they are incurred. 33 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) Provisions q) Provisions are recognised when the consolidated entity has a present (legal or constructive) obligation as a  result of a past event, it is probable that the consolidated entity will be required to settle the obligation, and a  reliable estimate can be made of the amount of the obligation.  The amount recognised as a provision is the best  estimate of the consideration required to settle the present obligation at the reporting date, taking into account  the risks and uncertainties surrounding the obligation.  If the time value of money is material, provisions are  discounted using a current pre‐tax rate specific to the liability.  The increase in the provision resulting from the  passage of time is recognised as a finance cost. r) Employee benefits Short‐term employee benefits Liabilities for wages and salaries, including non‐monetary benefits and annual leave expected to be settled  wholly within 12 months of the reporting date are measured at the amounts expected to be paid when the  liabilities are settled. Other long‐term employee benefits The liability for annual leave and long service leave not expected to be settled within 12 months of the reporting  date are measured at the present value of expected future payments to be made in respect of services provided  by employees up to the reporting date using the projected unit credit method. Consideration is given to  expected future wage and salary levels, experience of employee departures and periods of service. Expected  future payments are discounted using market yields at the reporting date on corporate bonds with terms to  maturity and currency that match, as closely as possible, the estimated future cash outflows. Share‐based payments Equity‐settled and cash‐settled share‐based compensation benefits are provided to employees.  Equity‐settled transactions are awards of shares, or options over shares, that are provided to employees in  exchange for the rendering of services. Cash‐settled transactions are awards of cash for the exchange of  services, where the amount of cash is determined by reference to the share price. The cost of equity‐settled transactions are measured at fair value on grant date. Fair value is independently  determined using either the Binomial or Black‐Scholes option pricing model that takes into account the exercise  price, the term of the option, the impact of dilution, the share price at grant date and expected price volatility of  the underlying share, the expected dividend yield and the risk free interest rate for the term of the option,  together with non‐vesting conditions that do not determine whether the consolidated entity receives the  services that entitle the employees to receive payment. No account is taken of any other vesting conditions. The cost of equity‐settled transactions are recognised as an expense with a corresponding increase in equity  over the vesting period. The cumulative charge to profit or loss is calculated based on the grant date fair value of  the award, the best estimate of the number of awards that are likely to vest and the expired portion of the  vesting period. The amount recognised in profit or loss for the period is the cumulative amount calculated at  each reporting date less amounts already recognised in previous periods. The cost of cash‐settled transactions is initially, and at each reporting date until vested, determined by applying  either the Binomial or Black‐Scholes option pricing model, taking into consideration the terms and conditions on  which the award was granted.  34 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) The cumulative charge to profit or loss until settlement of the liability is calculated as follows: • • during the vesting period, the liability at each reporting date is the fair value of the award at that date  multiplied by the expired portion of the vesting period; and from the end of the vesting period until settlement of the award, the liability is the full fair value of the  liability at the reporting date. All changes in the liability are recognised in profit or loss. The ultimate cost of cash‐settled transactions is the  cash paid to settle the liability. Market conditions are taken into consideration in determining fair value. Therefore any awards subject to  market conditions are considered to vest irrespective of whether or not that market condition has been met,  provided all other conditions are satisfied. If equity‐settled awards are modified, as a minimum an expense is recognised as if the modification has not  been made. An additional expense is recognised, over the remaining vesting period, for any modification that  increases the total fair value of the share‐based compensation benefit as at the date of modification. If the non‐vesting condition is within the control of the consolidated entity or employee, the failure to satisfy the  condition is treated as a cancellation. If the condition is not within the control of the consolidated entity or  employee and is not satisfied during the vesting period, any remaining expense for the award is recognised over  the remaining vesting period, unless the award is forfeited. If equity‐settled awards are cancelled, it is treated as if it has vested on the date of cancellation, and any  remaining expense is recognised immediately. If a new replacement award is substituted for the cancelled  award, the cancelled and new award is treated as if they were a modification. Fair value measurement s) When an asset or liability, financial or non‐financial, is measured at fair value for recognition or disclosure  purposes, the fair value is based on the price that would be received to sell an asset or paid to transfer a liability  in an orderly  transaction between market participants at the measurement date; and assumes that the  transaction will take place either: in the principal market; or in the absence of a principal market, in the most  advantageous market. Fair value is measured using the assumptions that market participants would use when pricing the asset or  liability, assuming they act in their economic best interests.  For non‐financial assets, the fair value measurement is based on its highest and best use. Valuation techniques  that are appropriate in the circumstances and for which sufficient data are available to measure fair value, are  used, maximising the use of relevant observable inputs and minimising the use of unobservable inputs. Assets and liabilities measured at fair value are classified, into three levels, using a fair value hierarchy that  reflects the significance of the inputs used in making the measurements. Classifications are reviewed at each  reporting date and transfers between levels are determined based on a reassessment of the lowest level of  input that is significant to the fair value measurement. 35 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) For recurring and non‐recurring fair value measurements, external valuers may be used when internal expertise  is either not available or when the valuation is deemed to be significant. External valuers are selected based on  market knowledge and reputation. Where there is a significant change in fair value of an asset or liability from  one period to another, an analysis is undertaken, which includes a verification of the major inputs applied in the  latest valuation and a comparison, where applicable, with external sources of data. Issued capital t) Ordinary shares are classified as equity. Incremental costs directly attributable to the issue of new shares or options are shown in equity as a deduction,  net of tax, from the proceeds. Dividends u) Dividends are recognised when declared during the financial year and no longer at the discretion of the  company. v) Earnings per share Basic earnings per share Basic earnings per share is calculated by dividing the profit attributable to the owners of Imagion Biosystems  Limited, excluding any costs of servicing equity other than ordinary shares, by the weighted average number of  ordinary shares outstanding during the financial year, adjusted for bonus elements in ordinary shares issued  during the financial year. Diluted earnings per share Diluted earnings per share adjusts the figures used in the determination of basic earnings per share to take into  account the after‐income tax effect of interest and other financing costs associated with dilutive potential  ordinary shares and the weighted average number of shares assumed to have been issued for no consideration  in relation to dilutive potential ordinary shares. w) Goods and Services Tax ('GST') and other similar taxes Revenues, expenses and assets are recognised net of the amount of associated GST, unless the GST incurred is  not recoverable from the tax authority. In this case it is recognised as part of the cost of the acquisition of the  asset or as part of the expense. Receivables and payables are stated inclusive of the amount of GST receivable or payable. The net amount of  GST recoverable from, or payable to, the tax authority is included in other receivables or other payables in the  statement of financial position. Cash flows are presented on a gross basis. The GST components of cash flows arising from investing or financing  activities which are recoverable from, or payable to the tax authority, are presented as operating cash flows. Commitments and contingencies are disclosed net of the amount of GST recoverable from, or payable to, the tax  authority. 36 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 1 Significant accounting policies (continued) Rounding of amounts x) The company is of a kind referred to in Corporations Instrument 2016/191, issued by the Australian Securities  and Investments Commission, relating to 'rounding‐off'.  Amounts in this report have been rounded off in  accordance with that Corporations Instrument to the nearest thousand dollars, or in certain cases, the nearest  dollar. New Accounting Standards and Interpretations not yet mandatory or early adopted Australian  y) Australian Accounting Standards and Interpretations that have recently been issued or amended but are not yet  mandatory, have not been early adopted by the consolidated entity for the annual reporting period ended 31  December 2020. The consolidated entity has not yet assessed the impact of these new or amended Accounting  Standards and Interpretations. 2 Critical Accounting Estimates, Assumptions and Judgements  The preparation of the financial statements requires management to make judgements, estimates and  assumptions that affect the reported amounts in the financial statements. Management continually evaluates its  judgements and estimates in relation to assets, liabilities, contingent liabilities, revenue and expenses.  Management bases its judgements, estimates and assumptions on historical experience and on other various  factors, including expectations of future events, management believes to be reasonable under the  circumstances. The resulting accounting judgements and estimates will seldom equal the related actual results.  The judgements, estimates and assumptions that have a significant risk of causing a material adjustment to the  carrying amounts of assets and liabilities (refer to the respective notes) within the next financial year are  discussed below. Fair value measurement hierarchy The consolidated entity is required to classify all assets and liabilities, measured at fair value, using a three level  hierarchy, based on the lowest level of input that is significant to the entire fair value measurement, being: Level  1: Quoted prices (unadjusted) in active markets for identical assets or liabilities that the entity can access at the  measurement date; Level 2: Inputs other than quoted prices included within Level 1 that are observable for the  asset or liability, either directly or indirectly; and Level 3: Unobservable inputs for the asset or liability.  Considerable judgement is required to determine what is significant to fair value and therefore which category  the asset or liability is placed in can be subjective. Estimation of useful lives of assets The consolidated entity determines the estimated useful lives and related depreciation and amortisation  charges for its property, plant and equipment and finite life intangible assets. The useful lives could change  significantly as a result of technical innovations or some other event. The depreciation and amortisation charge  will increase where the useful lives are less than previously estimated lives, or technically obsolete or non‐ strategic assets that have been abandoned or sold will be written off or written down. 37 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 2 Critical Accounting Estimates, Assumptions and Judgements (continued) Lease term The lease term is a significant component in the measurement of both the right‐of‐use asset and lease liability.  Judgement is exercised in determining whether there is reasonable certainty that an option to extend the lease  or purchase the underlying asset will be exercised, or an option to terminate the lease will not be exercised,  when ascertaining the periods to be included in the lease term. In determining the lease term, all facts and  circumstances that create an economical incentive to exercise an extension option, or not to exercise a  termination option, are considered at the lease commencement date. Factors considered may include the  importance of the asset to the consolidated entity's operations; comparison of terms and conditions to  prevailing market rates; incurrence of significant penalties; existence of significant leasehold improvements; and  the costs and disruption to replace the asset. The consolidated entity reassesses whether it is reasonably certain  to exercise an extension option, or not exercise a termination option, if there is a significant event or significant  change in circumstances. Incremental borrowing rate Where the interest rate implicit in a lease cannot be readily determined, an incremental borrowing rate is  estimated to discount future lease payments to measure the present value of the lease liability at the lease  commencement date. Such a rate is based on what the consolidated entity estimates it would have to pay a  third party to borrow the funds necessary to obtain an asset of a similar value to the right‐of‐use asset, with  similar terms, security and economic environment. 3 Operating segments Identification of reporting operating segments The consolidated entity is organised into one operating segment being Research & Development. This operating  segment is based on internal reports that are reviewed and used by the Board of Directors (who are identified as  the Chief Operating Decision Makers (CODM) in assessing performance and in determine the allocation of  resources). 38 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 4 Revenue  Sales revenue Sale of goods Other revenue: Interest Forgiveness of US Government authority loan Other revenue  2020 $   205,717 205,717 5,338 222,676 67,682 295,696 2019 $   410,854 410,854 21,788 ‐   72 21,860 501,413 432,714 Sale of goods includes $197,328 relating to contracted sales which were delivered at a point in time. Forgiveness of US Government authority loan relates to a loan provided by the US Small Business Association for  its Paycheck Protection Payment as part of COVID‐19 relief.  The Company, in accordance with eligibility  requirements, applied to have this loan forgiven in December 2020 and the Company received notification in  January 2021 that the loan and any associated interest had been forgiven in full. Other revenue includes $62,854 from the Australian Taxation Office in relation to cash flow boosts received as  part of COVID‐19 relief. 5 Expenses Depreciation: Plant and equipment Right‐of‐use assets Finance costs: Interest payable on hire purchase liabilities Unwinding of the lease liability interest Other interest 6 Cash and cash equivalents  Cash on hand Cash at bank Term deposits Note 8 9 11 11 2020 $   68,049 292,525 360,574 6,440 37,387 25 43,852 2019 $   118,186 23,802 141,988 5,137 3,557 464 9,158 2020 $   15 5,200,532 8,000,000 13,200,547 2019 $   16 3,401,697 ‐   3,401,713 Funds were placed on term deposit in December 2020 in two tranches for periods of three and six months.  They  are at call within 31 days notice and are therefore recorded as cash and cash equivalents. 39            Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 7 Other current assets Prepayments GST refundable Security deposits Other assets 8 Property, plant and equipment Plant and equipment, at cost Less: accumulated depreciation 2020 $   129,606 65,514 35,805 2,515 233,440 2019 $   97,977 25,748 43,644 3,743 171,112 2020 $   753,535 (593,103) 160,432 2019 $   1,032,534 (598,384) 434,150 Reconciliation Reconciliations of the written down values at the beginning and end of the current and previous financial years  are set out below: Opening balance Additions Assets written‐off Foreign currency revaluation movements Depreciation expense Closing balance 434,150 63,502 (120,331) (22,519) (194,371) 160,432 271,860 278,233 ‐   2,243 (118,186) 434,150 9 Right‐of‐use assets Land and buildings: right‐of‐use Less: accumulated depreciation 2020 $   808,738 (284,153) 524,585 2019 $   889,095 (24,044) 865,051 Reconciliation Reconciliations of the written down values at the beginning and end of the current and previous financial years  are set out below: Opening balance Additions Other Foreign currency revaluation movements Depreciation expense Closing balance 865,051 ‐   (13) (47,928) (292,525) 524,585 ‐   889,095 ‐   ‐   (24,044) 865,051 The consolidated entity leased land and buildings for its offices in December 2019 under an agreement of 25  months with an option to extend. The lease has various escalation clauses. On renewal, the terms of the lease are  renegotiated.  The consolidated entity leases office equipment under agreements of less than two years. These leases are either  short‐term or low‐value, so have been expensed as incurred and not capitalised as right‐of‐use assets. 40 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 10 Trade and other payables Trade payables Other payables and accruals 11 Lease liabilities Current Lease liability ‐ premises Hire purchase liabilities Non‐current Lease liability ‐ premises Hire purchase liabilities Information in relation to the lease liability ‐ premises is below: Maturity analysis ‐ contractual undiscounted cash flows Less than one year One to five years Total undiscounted lease liabilities Amounts recognised in profit and loss Interest on lease liabilities Amounts recognised in profit and loss Total cash outflow for leases 12 Employee benefits Current Provision for annual leave Non‐current Provision for long service leave 13 Other liabilities Make good provision 41 2020 $   288,301 113,789 402,090 2019 $   708,905 177,074 885,979 Interest rate 2020 $   2019 $   5.0% 6.6% 5.0% 5.0% 267,384 90,846 358,230 265,735 37,013 302,748 245,675 16,085 261,760 612,533 2,486 615,019 288,702 297,545 586,247 282,770 644,487 927,257 37,387 3,557 286,207 ‐   2020 $   2019 $   109,095 101,832 1,536 ‐   2020 $   31,438 2019 $   33,990 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 14 Issued capital Ordinary shares Ordinary shares entitle the holder to participate in dividends and the proceeds on the winding up of the company  in proportion to the number of and amounts paid on the shares held. The fully paid ordinary shares have no par  value and the company does not have a limited amount of authorised capital. Ordinary shares ‐ fully paid Movements in ordinary share capital ‐ 2019 Details Opening balance Issue of shares (performance rights) Issue of shares (performance rights) Issue of shares (share‐based payment) Issue of shares (exercise of options) Issue of shares (rights issue) Costs of capital raising Issue of shares (share‐based payment) Movements in ordinary share capital ‐ 2020 Details Opening balance Issue of shares (rights issue) Costs of capital raising Issue of shares (performance rights) Issue of shares (performance rights) Issue of shares (placement) Issue of shares Issue of shares (costs of capital raising) Costs of capital raising Issue of shares (exercise of options) Issue of shares (exercise of options) Issue of shares (performance rights) Issue of shares (exercise of options) Issue of shares (performance rights) Issue of shares (exercise of options) Issue of shares (placement) Costs of capital raising Issue of shares (exercise of listed options) Issue of shares (exercise of listed options) 2020 Shares 998,367,288 2019 Shares 511,282,191 2020 $   51,322,126 2019 $   36,904,580 Shares 322,742,824 962,500 31,250 3,445,310 187,500 181,412,807 ‐ 2,500,000 511,282,191 Shares 511,282,191 250,147,965 ‐ 150,000 200,000 111,111,111 1,000,000 ‐ ‐ 21,600,000 2,000,000 2,500,000 2,370,000 2,500,000 10,730,000 70,588,236 ‐ 7,062,785 5,125,000 998,367,288 Issue Price ‐ 0.160 0.160 0.050 0.039 0.020 ‐ 0.017 Issue Price ‐ 0.010 ‐ 0.060 0.060 0.045 0.050 ‐ ‐ 0.060 0.028 0.028 0.060 0.028 0.060 0.085 ‐ 0.030 0.050 $   33,182,325 154,000 5,000 172,266 7,266 3,628,256 (287,033) 42,500 36,904,580 $   36,904,580 2,501,480 (295,228) 9,375 12,500 5,000,000 50,000 (50,000) (667,963) 1,296,000 55,980 70,000 142,200 70,000 643,800 6,000,000 (888,731) 211,884 256,250 51,322,126 Date 1‐Jan‐19 24‐Jun‐19 30‐Sep‐19 30‐Sep‐19 4‐Oct‐19 26‐Nov‐19 26‐Nov‐19 10‐Dec‐19 31‐Dec‐19 Date 1‐Jan‐20 28‐Apr‐20 28‐Apr‐20 29‐Apr‐20 23‐Jun‐20 4‐Aug‐20 4‐Aug‐20 4‐Aug‐20 4‐Aug‐20 18‐Aug‐20 28‐Aug‐20 10‐Sep‐20 20‐Oct‐20 22‐Oct‐20 26‐Nov‐20 27‐Nov‐20 27‐Nov‐20 Various Various 31‐Dec‐20 42                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 14 Issued capital (continued) On 28 April 2020 the consolidated entity completed a rights issue that raised $2,501,480 (before costs) through  non‐renounceable rights issue of 250,147,965 shares at $0.01. On 29 April 2020, 150,000 vested performance shares were converted into ordinary shares.  The performance  shares were issued to a former director. On 23 June 2020, 200,000 vested performance shares were converted into ordinary shares.  The performance  shares were issued to current directors. On 4 August 2020 the consolidated entity completed a placement that raised $5,000,000 (before costs) through  the issue of 111,111,111 shares at $0.045.  1,000,000 ordinary shares were also issued as part of the costs of the  placement. On 18 August 2020, an option holder exercised 21,600,000 options and converted to ordinary shares. On 28 August 2020, an former employee exercised 2,000,000 options and converted to ordinary shares. On 10 September 2020, 2,500,000 vested performance shares were converted into ordinary shares.  The  performance shares were issued to the CEO. On 20 October 2020, an option holder exercised 2,370,000 options and converted to ordinary shares. On 22 October 2020, 2,500,000 vested performance shares were converted into ordinary shares.  The  performance shares were issued to the CEO. On 26 November 2020, option holders exercised 10,730,000 options and converted to ordinary shares. On 27 November 2020 the consolidated entity completed a placement that raised $6,000,000 (before costs)  through the issue of 70,588,236 shares at $0.085. On various dates throughout 2020 option holders exercised a total of 7,062,785 $0.03 listed options and  converted to ordinary shares. On various dates throughout 2020 option holders exercised a total of 5,125,000 $0.05 listed options and  converted to ordinary shares. Listed options As part of two separate renounceable rights issues (in November 2019 and April 2020) the Company issued listed  options.  In November 2019 'IBXO options' were issued with an exercise price of $0.05.  In April 2020 'IBXOA  options' were issues with an exercise price of $0.03.  IBXO options expire on 26 November 2021 and IBXOA  options expire on 28 April 2023.  Both IBXO and IBXOA options entitle the holder to convert one option to one  ordinary share upon application and payment. 43 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 14 Issued capital (continued) Movements in listed options during the current and previous financial year are set out below: 2019 Details Opening balance Options allotted post rights issue Closing balance 2020 Details Opening balance Options allotted post rights issue Options allotted follow‐on placement Options allotted to lead manager Options allotted to lead manager Options allotted to lead manager Options converted to ordinary shares Closing balance IBXO Options ‐ Date 1‐Jan‐19 96,706,395 26‐Nov‐19 31‐Dec‐19      96,706,395  IBXO Date 1‐Jan‐20 Options 96,706,395 Various (5,125,000) 31‐Dec‐20      91,581,395  IBXOA Options ‐ Date 1‐Jan‐20 28‐Apr‐20 27‐Jul‐20 27‐Jul‐20 6‐Aug‐20 27‐Nov‐20 Various 228,732,965 21,415,000 6,000,000 6,500,000 6,000,000 (7,062,785) 31‐Dec‐20    261,585,180  IBXOA options allotted on 27 July 2020 were in relation to the April 2020 right issue and were prescribed a value  of $26,460 included as part of the costs of capital raising. IBXOA options allotted on 6 August 2020 were in relation to the August 2020 placement and were prescribed a  value of $185,907 included as part of the costs of capital raising. IBXOA options allotted on 27 November 2020 were in relation to the November 2020 placement and were  prescribed a value of $510,000 included as part of the costs of capital raising. Capital risk management The consolidated entity's objectives when managing capital is to safeguard its ability to continue as a going  concern, so that it can provide returns for shareholders and benefits for other stakeholders and to maintain an  optimum capital structure to reduce the cost of capital. Capital is regarded as total equity, as recognised in the statement of financial position, plus net debt. Net debt is  calculated as total borrowings less cash and cash equivalents. 15 Reserves Foreign currency translation reserve Share based payment reserve 2020 $   (59,573) 1,660,862 1,601,289 2019 $   32,662 681,816 714,478 Foreign currency translation reserve The reserve is used to recognise exchange differences arising from the translation of the financial statements of  foreign operations to Australian dollars. It is also used to recognise gains and losses on hedges of the net  investments in foreign operations.  44                                                                                              Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 15 Reserves (continued) Movements in reserves Movements in each class of reserve during the current and previous financial year are set out below: Balance as at 1 January 2019 Movements in revaluation of foreign currency Share based payments for key management, non‐executive  directors and employees Conversion to share capital Balance at 31 December 2019 Balance as at 1 January 2020 Movements in revaluation of foreign currency Share based payment for lead managers and advisors Share based payment for suppliers Share based payments for key management, non‐executive  directors and employees Conversion to share capital Balance at 31 December 2020 16 Accumulated losses Accumulated losses at the beginning of the financial year Losses after income tax expense for the year Accumulated losses at the end of the financial year 17 Key management personnel Share based  payment  reserve $   1,796,992 Foreign  currency  reserve $   102,946 Total $   1,899,938 ‐ (70,284) (70,284) (954,160) (161,016) 681,816 Share based  payment  reserve $   681,816 ‐ 722,368 37,212 381,341 (161,875) 1,660,862 ‐   ‐   32,662 Foreign  currency  reserve $   32,662 (92,235) (954,160) (161,016) 714,478 Total $   714,478 (92,235) 722,368 37,212 ‐   ‐   (59,573) 381,341 (161,875) 1,601,289 2020 $   (34,645,541) (5,364,007) (40,009,548) 2019 $   (31,213,035) (3,432,506) (34,645,541) Compensation The aggregate compensation made to directors and other members of key management personnel of the  consolidated entity is set out below: Short‐term employee benefits Share based payments 2020 $   723,292 217,427 940,719 2019 $   723,533 (1,057,963) (334,430) Share based payments for the year ended 31 December 2019 is a negative amount, reflecting the reversal of  performance rights following a reassessment of the probabilities related to milestone achievement. 45                                                                                                                                                                                     Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 18 Remuneration of auditors During the financial year the following fees were paid or payable for services provided by RSM Australia Partners,  the auditor of the company, its network firms and unrelated firms: Audit services ‐ RSM Australia Partners Audit or review of the financial statements Other services in relation to adoption of AASB 16 and option valuation advice 2020 $   67,000 4,700 71,700 2019 $   60,000 ‐   60,000 19 Commitments The consolidated entity had contracted commitments for services in relation to its MagSenseTM HER2 breast  cancer Phase I first‐in‐human study totalling $718,821.  These expenses are expected to be incurred in 2021.  The  consolidated entity had no other commitments (2019: $nil). 20 Parent entity information Set out below is the supplementary information about the parent entity. Statement of profit or loss and other comprehensive income (Loss) after income tax Total comprehensive income Statement of financial position Total current assets Total assets Total current liabilities Total liabilities Equity    Issued capital    Reserves    Retained earnings Total equity 2020 $   (4,117,825) 2019 $   (3,868,212) (4,117,825) (3,868,212) 2020 $   11,296,821 2019 $   3,185,926 11,296,834 3,370,893 364,414 614,362 365,950 614,362 51,322,126 1,947,990 (42,339,232) 10,930,884 36,488,486 1,385,037 (35,116,992) 2,756,531 Contingent liabilities The parent entity had no contingent liabilities as at 31 December 2020 and 31 December 2019. Capital commitments  The parent entity had contracted commitments for services in relation to its MagSenseTM HER2 breast cancer  Phase I first‐in‐human study totalling $718,821.  These expenses are expected to be incurred in 2021.  The parent  entity had no other commitments (2019: $nil). 46 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 20 Parent entity information (continued) Significant accounting policies The accounting policies of the parent entity are consistent with those of the consolidated entity, as disclosed in  note 1, except for the following: • Investments in subsidiaries are accounted for at cost, less any impairment, in the parent entity. 21 Interests in subsidiaries The consolidated financial statements incorporate the assets, liabilities and results of the following wholly owned  subsidiaries in accordance with the accounting policy described in note 1: Name Imagion Biosystems Inc Principal place of business /  Country of incorporation Unites States of America 22 Reconciliation of loss after income tax to net cash flows from operating activities Ownership interest 2020 % 100 2020 $   2019 % 100 2019 $   Loss after income tax expense for the year (5,364,007) (3,432,506) Adjustments for: Depreciation expense Assets written‐off Refundable deposit Foreign exchange loss Share based payments expense Direct equity raising costs Interest Insurance hire purchase Loan forgiveness Bad debts Equity settled payments Changes in operating assets and liabilities: Trade and other receivables Trade and other payables Monies in trust 23 Earnings per share Loss after income tax 360,574 120,331 ‐   61,283 399,145 ‐   ‐   249,875 (222,676) ‐   24,425 (4,371,050) (66,000) (186,040) ‐   (4,623,090) 2020 $   (5,364,007) Loss after income tax attributable to the owners of Imagion Biosystems Limited (5,364,007) 47 142,230 ‐   123,112 32,837 (940,754) 7,882 5,657 ‐   ‐   4,945 180,852 (3,875,745) (20,900) (298,909) 13,509 (4,182,045) 2019 $   (3,432,506) (3,432,506)             Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 23 Earnings per share (continued) Weighted average number of ordinary shares used in calculating basic earnings  per share 747,075,458 342,221,471 Weighted average number of ordinary shares used in calculating diluted  earnings per share 747,075,458 342,221,471 2020 Number 2019 Number Loss after income tax Loss after income tax attributable to the owners of Imagion Biosystems Limited 24 Share based payments 2020 Cents (0.007) (0.007) 2019 Cents (0.010) (0.010) Performance shares  Since listing on the Australian Stock Exchange, the consolidated entity has established various incentive  arrangements to assist in the attraction, retention and motivation of its employee and management group. Employees No performance rights were issued to employees in 2020 (2019: nil). On 24 June 2019, 62,500 rights were converted into ordinary shares to an employee. On 30 September 2019, 31,250 rights were converted into ordinary shares to an employee. There are no performance rights outstanding for employees at end of 2020 (2019:nil). Key management personnel and directors A total of 15,000,000 rights over shares were issued to key management personnel and directors (10,000,000 on  6 August 2020 and 5,000,000 on 9 December 2020).  These rights vest three years after the date of issue with all  15,000,000 rights being subject to performance milestones.  Each right is convertible into one ordinary share  upon vesting.  Performance rights are unquoted. On 29 April 2020, 150,000 rights were converted into ordinary shares to a former director. On 23 June 2020, 200,000 rights were converted into ordinary shares to directors. On 10 September 2020, 2,500,000 rights were converted into ordinary shares upon achievement of a  performance milestone. On 22 October 2020, 2,500,000 rights were converted into ordinary shares upon achievement of a performance  milestone. 10,400,000 rights lapsed during the year due to non‐achievement of milestones. 48       Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 24 Share based payments (continued) 2019 1 January 2019 Issued Vested ‐ based on employment Converted to shares Balance 31 December 2019 Employees Directors & Key Management Unvested 62,500 ‐ (62,500) ‐ ‐ Vested 31,250 ‐ 62,500 (93,750) ‐ Unvested 11,650,000 ‐ (900,000) ‐ 10,750,000 Vested / not  exercised ‐ ‐ 900,000 (900,000) ‐ 2020 Issued Vested ‐ based on employment Vested ‐ based on achievement of milestones Lapsed ‐ due to non‐achievement of milestones Converted to shares Balance 31 December 2020 ‐ ‐ ‐ ‐ ‐ ‐ ‐ ‐ ‐ ‐ ‐ ‐ 15,000,000 (350,000) (5,000,000) (10,400,000) ‐ 350,000 5,000,000 ‐ ‐ (5,350,000) 10,000,000 ‐ Options A share option plan has been established by the consolidated entity and approved by shareholders at a general  meeting, whereby the consolidated entity may, at the discretion of the Board, grant options over ordinary shares  in the company to certain key management personnel of the consolidated entity. The options are issued for nil  consideration and are granted in accordance with performance guidelines established by the Board. Employees A total of 10,150,000 options were issued to employees on 29 September 2020.  The options have an exercise  price of $0.0909 and vest monthly over three years with expiry dates between 30 September 2025 and 30  September 2028. Key management personnel and directors A total of 6,000,000 options were issued to key management personnel on 1 June 2020.  The options have an  exercise price of $0.028 with one third vesting on 1 May 2021, another third vesting on 1 May 2022 and another  third vesting on 1 May 2023.  Expiry dates are 1 May 2026 to 1 May 2028. A total of 2,500,000 options were issued to directors on 1 June 2020.  The options have an exercise price of  $0.028 with half vesting on 1 May 2021, and the other half vesting on 1 May 2022.  Expiry dates are 1 May 2026  and 1 May 2027. A total of 3,000,000 options were issued to key management personnel on 9 December 2020.  The options have  an exercise price of $0.14 with one third vesting on 30 November 2021, another third vesting on 30 November  2022 and another third vesting on 30 November 2023.  Expiry dates are 30 November 2026 to 30 November  2028. 49                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 24 Share based payments (continued) Set out below are summaries of options granted under the plans: 2020 Grant  date Expiry  date 24‐Jun‐19 24‐Jun‐24 1‐May‐26 1‐Jun‐20 1‐May‐27 1‐Jun‐20 1‐May‐28 1‐Jun‐20 29‐Sep‐20 30‐Sep‐28 9‐Dec‐20 30‐Nov‐26 9‐Dec‐20 30‐Nov‐27 9‐Dec‐20 30‐Nov‐28 Exercise  price Balance at  1‐Jan‐2020 $0.028 4,650,000 $0.028 $0.028 $0.028 $0.091 $0.140 $0.140 $0.140 ‐ ‐ ‐ ‐ ‐ ‐ 4,650,000 Granted ‐ Exercised (2,000,000) 3,250,000 3,250,000 2,000,000 10,150,000 1,000,000 1,000,000 1,000,000 21,650,000 ‐ ‐ ‐ ‐ ‐ ‐ ‐ (2,000,000) Expired /  forfeited /  other (500,000) ‐ ‐ ‐ ‐ ‐ ‐ ‐ (500,000) Balance at 31‐ Dec‐2020 2,150,000 3,250,000 3,250,000 2,000,000 10,150,000 1,000,000 1,000,000 1,000,000 23,800,000 Weighted average exercise price $0.028 $0.073 $0.028 ‐ $0.069 2019 Grant  date Expiry  date 24‐Jun‐19 24‐Jun‐24 Exercise  price $0.028 Weighted average exercise price Balance at  1‐Jan‐2019 ‐ ‐ Granted 5,300,000 Exercised (187,500) Expired /  forfeited /  other (462,500) Balance at 31‐ Dec‐2019 4,650,000 $0.028 $0.028 $0.028 $0.028 Set out below are the options exercisable at the end of the financial year: Grant date Expiry date 24‐Jun‐19 24‐Jun‐24 29‐Sep‐20 30‐Sep‐28 2020 Number 2019 Number 2,150,000 845,833 2,995,833 3,475,000 ‐   3,475,000 The weighted average share price during the financial year was $0.062 (2019: $0.033). The weighted average remaining contractual life of options outstanding at the end of the financial year was 6.08  years (2019: 4.48 years). 50                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 24 Share based payments (continued) For the options granted during the current and previous financial year, the valuation model inputs used to  determine the fair value at the grant date, are as follows: Share  price at  grant  date $0.017 $0.028 $0.028 $0.028 $0.083 $0.125 $0.125 $0.125 Grant  date Expiry  date 24‐Jun‐19 24‐Jun‐24 1‐May‐26 1‐Jun‐20 1‐May‐27 1‐Jun‐20 1‐May‐28 1‐Jun‐20 29‐Sep‐20 30‐Sep‐28 9‐Dec‐20 30‐Nov‐26 9‐Dec‐20 30‐Nov‐27 9‐Dec‐20 30‐Nov‐28 25 Financial instruments Exercise  price $0.028 $0.028 $0.028 $0.028 $0.091 $0.140 $0.140 $0.140 Expected  volatility Dividend yield 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 87.00% 110.00% 110.00% 110.00% 110.00% 110.00% 110.00% 110.00% Fair value at  Risk‐free  grant date interest rate 0.92% $0.011 0.04% $0.010 0.04% $0.014 0.04% $0.016 0.36% $0.047‐$0.064 0.43% $0.045 0.43% $0.064 0.43% $0.077 The consolidated entity’s activities expose it to a variety of financial risks: market risk (including foreign currency  risk, price risk and interest rate risk), credit risk and liquidity risk. The consolidated entity’s overall risk  management program focuses on the unpredictability of financial markets and seeks to minimize potential  adverse effects on the financial performance of the consolidated entity. The consolidated entity uses different  methods to measure different types of risk to which it is exposed. These methods include sensitivity analysis in  the case of interest rate, foreign exchange and other price risks, ageing analysis for credit risk and beta analysis in  respect of investment portfolios to determine market risk.  Derivatives are not currently used by the consolidated entity for hedging purposes. The consolidated entity does  not speculate in the trading of derivative instruments.   Market risk Foreign currency risk The consolidated entity undertakes certain transactions denominated in foreign currency and is exposed to  foreign currency risk through foreign exchange rate fluctuations, in particular United States dollars.  Foreign exchange risk arises from future commercial transactions and recognised financial assets and financial  liabilities denominated in a currency that is not the entity’s functional currency. The risk is measured using  sensitivity analysis and cash flow forecasting.  The consolidated entity had net assets denominated in foreign currencies of $1,982,996 (assets of $2,822,183 less  liabilities of $829,187) as at 31 December 2020 (2019: Net assets $216,998 (assets of $1,501,217 less liabilities of  $1,284,219)). Based on this exposure, had the Australian dollar weakened by 5%/strengthened by 5% (2019:  weakened by 5%/strengthened by 5%) against these foreign currencies with all other variables held constant, the  consolidated entity's loss before tax for the year would have been $99,150 lower/$99,150 higher (2019: $10,850  lower/$10,850 higher) . 51 Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 25 Financial instruments (continued) The carrying amount of the consolidated entity’s foreign currency denominated financial assets and financial  liabilities at the reporting date were as follows (holdings are shown in AUD equivalent): US dollars Assets Liabilities 2020 2,822,183 2019 1,501,217 2020 839,187 2019 1,284,218 Price risk The Consolidated Entity is not exposed to any significant price risk.  Credit risk Credit risk refers to the risk that the counter party will default on its contractual obligations resulting in financial  loss to the consolidated entity. Credit risk is the risk of financial loss to the consolidated entity if a customer or  counterparty to a financial instrument fails to meet its contractual obligations and arises principally from the  consolidated entity’s receivables from customers and investment securities. The consolidated entity has only  minimal sales revenue and consequently does not have credit exposure to outstanding receivables.  Interest rate risk Interest rate risk is the risk that the value of a financial instrument or cash flows associated with the instrument  will fluctuate due to changes in market interest rates. Interest rate risk arises from fluctuations in interest bearing  financial assets and liabilities that the consolidated entity uses. Interest bearing assets comprise cash and cash  equivalents which are considered to be short‐term liquid assets and investment decisions are governed by the  monetary policy.  During the year, the consolidated entity had no variable rate interest bearing liability. It is the consolidated  entity's policy to settle trade payables within the credit terms allowed and therefore not incur interest on  overdue balances. Liquidity risk Liquidity risk is the risk that the consolidated entity will not be able to meet its financial obligations as they fall  due. The consolidated entity’s approach to managing liquidity is to ensure, as far as possible, that it will always  have sufficient liquidity to meet its liabilities when due, under both normal and stressed conditions, without  incurring unacceptable losses or risking damage to the consolidated entity’s reputation. The consolidated entity’s  objective is to maintain a balance between continuity of funding and flexibility. The consolidated entity’s  exposure to financial obligations relating to corporate administration and projects expenditure, are subject to  budgeting and reporting controls, to ensure that such obligations do not exceed cash held and known cash  inflows for a period of at least 1 year. Remaining contractual maturities The following tables detail the consolidated entity’s remaining contractual maturity for its financial instrument  liabilities. The tables have been drawn up based on the undiscounted cash flows of financial liabilities based on  the earliest date on which the financial liabilities are required to be paid. The tables include both interest and  principal cash flows disclosed as remaining contractual maturities and therefore these totals may differ from their  carrying amount in the statement of financial position.  52                                   Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 25 Financial instruments (continued) 2020 Non‐interest bearing Trade payables Other payables Interest bearing Lease liability Hire purchase liability 2019 Non‐interest bearing Trade payables Other payables Interest bearing Lease liability Weighted  average  % 1 year or  less $ Between 1  and 2 years $ Between 2  and 5 years $ Over 5 years $ Total $ 288,301 113,789 267,384 90,846 760,320 5.0% 6.1% ‐ ‐ 265,735 12,050 277,785 ‐ ‐ ‐ 24,963 24,963 ‐ ‐ ‐ ‐ ‐ 288,301 113,789 533,119 127,859 1,063,068 Weighted  average  % 1 year or  less $ Between 1  and 2 years $ Between 2  and 5 years $ Over 5 years $ Total $ 708,905 177,074 ‐ ‐ ‐ ‐ 5.0% 262,257 1,148,236 296,476 296,476 318,587 318,587 ‐ ‐ ‐ ‐ 708,905 177,074 877,320 1,763,299 The cash flows in the maturity analysis above are not expected to occur significantly earlier than contractually  disclosed above.  26 Fair value measurement The following tables detail the consolidated entity’s assets and liabilities, measured or disclosed at fair value,  using a three‐level hierarchy, based on the lowest level of input that is significant to the entire fair value  measurement, being: Level 1: Quoted prices (unadjusted) in active markets for identical assets or liabilities that the entity can access at  the measurement date Level 2: Inputs other than quoted prices included within Level 1 that are observable for the asset or liability,  either directly or indirectly Level 3: Unobservable inputs for the asset or liability The carrying amounts of trade and other receivables and trade and other payables are assumed to approximate  their fair values due to their short‐term nature.  The fair value of financial liabilities are estimated by discounting  the remaining contractual maturities at the current market interest rate that is available for similar financial  liabilities. Valuation techniques for fair value measurements categorised within level 2. Unquoted investments have been valued using a discounted cash flow model.  Derivative financial instruments have been valued using quoted market rates. This valuation technique maximises  the use of observable market data where it is available and relies as little as possible on entity specific estimates. 53                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    Imagion Biosystems Limited Notes to the Financial Statements For the year ended 31 December 2020 27 Income tax benefit 2020 $   2019 $   Tax losses not recognised Unused tax losses for which no deferred tax asset has been recognised (Australia) 7,742,871 9,384,665 Potential tax benefit at 26.0% for 2020 and 27.5% for 2019  2,013,146 2,580,783 Unused tax losses for which no deferred tax asset has been recognised (USA) 9,587,222 8,794,261 The above potential tax benefit for tax losses has not been recognised in the statement of financial position.  These tax losses can only be utilised in the future if the company satisfies the relevant tax loss rules in the  relevant jurisdictions and the Company earns sufficient taxable profit to absorb the losses.  28 Contingent liabilities As of 31 December 2020, the Company was not party to any material litigation, claims or suit whose outcome  could have a material effect on the financial statements (31 December 2019: Nil). 29 Related party transactions Parent entity Imagion Biosystems Limited is the parent entity. Subsidiaries Interest in subsidiaries are set out in Note 21. Key management personnel Disclosures relating to key management personnel are set out in note 18 and the remuneration report included in  the directors' report. Transactions with related parties The following transactions occurred with related parties: Payment for contracting services ‐ Bronwyn Le Grice 2020 $   5,000 2019 $   25,000 Receivable from and payable to related parties The following balances are outstanding at the reporting date in relation to transactions with related parties: Trade payables to David Ludvigson Trade payables to Michael Harsh Trade payables to Jovanka Naumoska Trade payables to Mark Van Asten 30 Events after the reporting period 2020 $   ‐   ‐   ‐   ‐   2019 $   20,554 24,122 27,080 27,080 No other matters or circumstances have arisen since the end of the financial period that has significantly affected  or may significantly affect the operations of the consolidated entity, the results of those operations, or the state  of affairs of the consolidated entity in future financial years. 54                         Imagion Biosystems Limited Directors' Declaration For the year ended 31 December 2020 In the directors' opinion: • • • • the attached financial statements and notes and the remuneration disclosures that are contained within the Remuneration report within the Directors' report comply with the Corporations Act 2001 , the Accounting Standards, the Corporations Regulations 2001  and other mandatory professional reporting requirements; the attached financial statements and notes comply with International Financial Reporting Standards as issued by the International Accounting Standards Board as described in note 1 to the financial statements; the attached financial statements and notes give a true and fair view of the consolidated entity's financial position as at 31 December 2020 and of its performance for the financial year ended on that date; and there are reasonable grounds to believe that the company will be able to pay its debts as and when they become due and payable. The directors have been given the declarations required by section 295A of the Corporations Act 2001. Signed in accordance with a resolution of directors made pursuant to section 295(5)(a) of the Corporations Act  2001. On behalf of the directors Robert Proulx Executive Chair Imagion Biosystems Limited 25 February 2021 55     INDEPENDENT AUDITOR’S REPORT To the Members of Imagion Biosystems Limited Opinion We have audited the financial report of Imagion Biosystems Limited (the Company) and its subsidiaries (the Consolidated Entity), which comprises the consolidated statement of financial position as at 31 December 2020, the consolidated statement of profit or loss and other comprehensive income, the consolidated statement of changes in equity and the consolidated statement of cash flows for the year then ended, and notes to the financial statements, including a summary of significant accounting policies, and the directors' declaration. In our opinion the accompanying financial report of the Consolidated Entity is in accordance with the Corporations Act 2001, including: (I) giving a true and fair view of the Consolidated Entity’s financial position as at 31 December 2020 and of its financial performance for the year then ended; and (ii) complying with Australian Accounting Standards and the Corporations Regulations 2001. Basis for Opinion We conducted our audit in accordance with Australian Auditing Standards. Our responsibilities under those standards are further described in the Auditor's Responsibilities for the Audit of the Financial Report section of our report. We are independent of the Consolidated Entity in accordance with the auditor independence requirements of the Corporations Act 2001 and the ethical requirements of the Accounting Professional and Ethical Standards Board's APES 110 Code of Ethics for Professional Accountants (the Code) that are relevant to our audit of the financial report in Australia. We have also fulfilled our other ethical responsibilities in accordance with the Code. We confirm that the independence declaration required by the Corporations Act 2001, which has been given to the directors of the Company, would be in the same terms if given to the directors as at the time of this auditor's report. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion. Key Audit Matters Key audit matters are those matters that, in our professional judgement, were of most significance in our audit of the financial report of the current period. These matters were addressed in the context of our audit of the financial report as a whole, and in forming our opinion thereon, and we do not provide a separate opinion on these matters. We have determined the matters described below to be the key audit matters to be communicated in our report. 56 Key Audit Matters (continued) Key Audit Matter How our audit addressed this matter Fair Value of the share-based payments Refer to Note 24 in the financial statements In prior periods and in the current period IBX awarded share-based payments in the form of performance rights and share options. In addition, in the current financial period several employees and non-executive directors converted their performance rights and options to shares. There is an element of subjectivity in management’s assessment regarding the achievement of vesting conditions relating to the performance rights. We identified share-based payments as a key audit area due the complexity in the valuation of the options and performance rights issued. Going Concern IBX has been Historically, loss-making, has significant cash outflows and is dependent on continued support from investors through ongoing capital raises to fund research and development activities during its current start-up phase. We noted key financial indicators for the period such as operating losses, and operating cash outflows of $7.1m for the 12 months. IBX had cash reserves of approximately $13.2m as 31 December 2020 to cover IBX’s forecast cash burn for the upcoming financial year of approximately $11m. We included the going concern assumption as a key audit matter as the company relies on external support to cover its planned expenditure. Our audit procedures included, among others: vesting conditions specialists estimates for Reviewing the minutes of directors' meetings and ASX announcements for the approvals in relation to the granting of the instruments; Reviewing the key terms and conditions of the share-based payment arrangements; of Reviewing managements achieving the performance rights issued based on the performance in the current period; Involving our in valuation assessing the key assumptions used in the valuations model including the risk free rate relevant share prices of the company and volatility rates reflecting likely share price movements over the life of the option; reasonableness of key Challenging assumptions used by management relative to the valuation at the grant date; Verifying the mathematical accuracy of the computation; and Reviewing the adequacy and accuracy of the relevant financial statements. disclosures the the in Reviewing the current financial position of IBX; Reviewing ASX announcements, board minutes and all other relevant documentation to assess the entities progress with its research activities; Reviewing managements’ forecasts for the expected results for a period of twelve months from the date of signing the financial statements, the accuracy and the assumptions used; assessing including Understanding forecast expenditure committed and what could be considered discretionary; and the Considering potential downside scenarios and the resultant impact on available funds. - - - - - - - - - - - - 57 Other Information The directors are responsible for the other information. The other information comprises the information included in the Consolidated Entity’s annual report for the year ended 31 December 2020 but does not include the financial report and the auditor's report thereon. Our opinion on the financial report does not cover the other information and accordingly we do not express any form of assurance conclusion thereon. In connection with our audit of the financial report, our responsibility is to read the other information and, in doing so, consider whether the other information is materially inconsistent with the financial report or our knowledge obtained in the audit or otherwise appears to be materially misstated. If, based on the work we have performed, we conclude that there is a material misstatement of this other information, we are required to report that fact. We have nothing to report in this regard. Responsibilities of the Directors for the Financial Report The directors of the Company are responsible for the preparation of the financial report that gives a true and fair view in accordance with Australian Accounting Standards and the Corporations Act 2001 and for such internal control as the directors determine is necessary to enable the preparation of the financial report that gives a true and fair view and is free from material misstatement, whether due to fraud or error. In preparing the financial report, the directors are responsible for assessing the ability of the Consolidated Entity to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless the directors either intend to liquidate the Consolidated Entity or to cease operations, or have no realistic alternative but to do so. Auditor's Responsibilities for the Audit of the Financial Report Our objectives are to obtain reasonable assurance about whether the financial report as a whole is free from material misstatement, whether due to fraud or error, and to issue an auditor's report that includes our opinion. Reasonable assurance is a high level of assurance, but is not a guarantee that an audit conducted in accordance with the Australian Auditing Standards will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of this financial report. A further description of our responsibilities for the audit of the financial report is located at the Auditing and Assurance Standards Board website at: http://www.auasb.gov.au/auditors_responsibilities/ar2.pdf. This description forms part of our auditor's report. Report on the Remuneration Report Opinion on the Remuneration Report We have audited the Remuneration Report included in the directors' report for the year ended 31 December 2020. In our opinion, the Remuneration Report of Imagion Biosystems Limited, for the year ended 31 December 2020, complies with section 300A of the Corporations Act 2001. 58 Report on the Remuneration Report (continued) Responsibilities The directors of the Company are responsible for the preparation and presentation of the Remuneration Report in accordance with section 300A of the Corporations Act 2001. Our responsibility is to express an opinion on the Remuneration Report, based on our audit conducted in accordance with Australian Auditing Standards. RSM AUSTRALIA PARTNERS R B MIANO Partner Dated: 25 February 2021 Melbourne, Victoria 59 Imagion Biosystems Limited Shareholder Information For the year ended 31 December 2020 Corporate Governance Statement The Company's Directors and management are committed to conducting the business of the Group in an ethical  manner and in accordance with the highest standards of corporate governance.  The Company has adopted and  substantially complies with the ASX Corporate Governance Principles and Recommendations  (Fourth Edition)  (Recommendations) to the extent appropriate to the size and nature of the Group's operations. The Company has prepared a statement which sets out the corporate governance practices that were in operation  throughout the financial year for the Company, identifies any Recommendations that have not been followed, and  provides reasons for not following such Recommendations (Corporate Governance Statement). In accordance with ASX Listing Rules 4.10.3 and 4.7.4, the Corporate Governance Statement will be available for review  on the Company's website (www.imagionbiosystems.com), and will be lodged together with an Appendix 4G with the  ASX at the same time that this Annual Report is lodged with the ASX. The Appendix 4G will particularise each Recommendation that needs to be reported against by the Company and will  provide shareholders with information as to where relevant governance disclosures can be found. The Company's corporate governance policies and charters are all available on the Company's website  (www.imagionbiosystems.com). Additional Securities Information In accordance with ASX Listing Rule 4.10, the Company provides the following information to shareholders no  elsewhere disclosed in this Annual Report.  The information provided is current as at 23 February 2021 (Reporting  Date). Quoted equity securities ‐ ordinary shares As at the Reporting Date, the Company had a total of 1,022,104,180 fully paid ordinary shares on issue.  The  Company's shares are quoted on the ASX, and form the only class of securities on issue in the Company that is quoted  on the ASX, and that carries voting rights. At a general meeting of the Company, every holder of ordinary shares is entitled to vote in person or by proxy or  attorney; and on a show of hands (every person present who is a member has one vote); and on a poll (every person  present in person or by proxy or attorney has one vote for each ordinary share they hold). Range of holdings An analysis of the number of shareholders in the Company by size of holding is as follows: Share Range 1‐1,000 1,001‐5,001 5,001‐10,000 10,001‐100,000 100,001 and over Total Number of  Holders 54 1,233 1,711 4,939 1,457 9,394 Units 10,044 4,508,458 13,133,307 184,297,279 825,830,741 1,027,779,829 % 0.001% 0.439% 1.278% 17.932% 80.351% 100.000% Unmarketable Parcels The number of shareholders holding less than a marketable parcel of shares as at the Reporting Date (based on a  closing price of $0.20 per share) was 159. 60                                                                                                                                              Imagion Biosystems Limited Shareholder Information For the year ended 31 December 2020 Top 20 Shareholders The names of the 20 largest holders of ordinary shares as at the Reporting Date are listed below: Name Rank                 HSBC CUSTODY NOMINEES (AUSTRALIA) LIMITED                 HSBC CUSTODY NOMINEES (AUSTRALIA) LIMITED                 CITICORP NOMINEES PTY LIMITED                 THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM                 MR ANTHONY FAILLACE                 MR HAOJIE LI                 G & D FINN PTY LTD J P MORGAN NOMINEES AUSTRALIA PTY LIMITED                 MR ANESTIS LAZARIDIS              MR YUSUF KUCUKBAS               MR GREGORY JOHN HOWLETT & MRS MARGARET WILHELMINA HOW              MR ROBERT REVELEY BNP PARIBAS NOMINEES PTY LTD  BAIRDOS PTY LTD ROOKHARP CAPITAL PTY LIMITED E & W NOMINEE PTY LTD               MR FEERAS NAJJAR  HAWGOOD PTY LTD              MR YOANTO WAKIMIN DR RUSSELL KAY HANCOCK Total 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 No. of shares 56,856,953 35,978,808 22,674,960 10,529,053 10,361,838 9,850,000 8,000,000 7,596,510 7,583,365 7,400,000 6,740,000 6,100,000 5,294,200 5,000,000 5,000,000 4,750,000 4,500,000 4,435,294 4,307,260 4,000,000 226,958,241 % 5.532% 3.501% 2.206% 1.024% 1.008% 0.958% 0.778% 0.739% 0.738% 0.720% 0.656% 0.594% 0.515% 0.486% 0.486% 0.462% 0.438% 0.432% 0.419% 0.389% 22.082% Balance of register Grand total 800,821,588 1,027,779,829 77.918% 100.000% Substantial Shareholders There were no substantial holders of shares in the Company as at the Reporting Date. Escrowed securities There are no escrowed securities in the Company as at the Reporting Date. Unquoted equity securities The Company has two classes of unquoted equity securities on issue, being Performance Rights and Options. Performance Rights The Performance Rights will vest into ordinary shares (on a 1‐for‐1 basis), subject to satisfaction of prescribed vesting  conditions. None of the Performance Rights carry any voting rights.  However, any underlying shares issued upon the vesting or  conversion of the Performance Rights will carry equal voting rights with the other share on issue in the Company. As at the Reporting Date, there were a total of 10,000,000 Performance Rights on issue, held by two holders. 61                                                                                                                                                                                                                                                                                                         Imagion Biosystems Limited Shareholder Information For the year ended 31 December 2020 An analysis of the number of Performance Rights holders by size of holding is as follows: Range 1‐1,000 1,001‐5,001 5,001‐10,000 10,001‐100,000 100,001 and over Total Number of  Holders ‐ ‐ ‐ ‐ Units ‐ ‐ ‐ ‐ 2 2 10,000,000 10,000,000 % 0.000% 0.000% 0.000% 0.000% 100.000% 100.000% Options The Options upon exercise will convert into ordinary shares (on a 1‐for‐1 basis), subject to various exercise prices and  expiry dates. None of the Options carry any voting rights.  However, any underlying shares issued upon the vesting or conversion of  the Options will carry equal voting rights with the other share on issue in the Company. As at the Reporting Date, there were a total of 326,740,638 Options on issue, held by 992 holders. An analysis of the number of Option holders by size of holding is as follows: Range 1‐1,000 1,001‐5,001 5,001‐10,000 10,001‐100,000 100,001 and over Total Number of  Holders 6 27 57 435 467 992 Units 1,529 109,419 451,058 21,820,896 304,357,736 326,740,638 % 0.000% 0.033% 0.138% 6.678% 93.150% 100.000% 62                                                                                                                                                                                                                                                                                                                                                                                                                           Imagion Biosystems Limited Corporate Directory For the year ended 31 December 2020 Corporate Directory Directors Mr Robert Proulx Mr Michael Harsh Mr David Ludvigson Ms Jovanka Naumoska Mr Mark Van Asten Ms Dianne Angus Ms Bronwyn Le Grice Company Secretary Mr Geoff Hollis Executive Chairman / President Non‐Executive Director Non‐Executive Director Non‐Executive Director Non‐Executive Director Non‐Executive Director Non‐Executive Director Appointed 8 May 2020 Resigned 31 March 2020 Registered Office c/o ‐ K&L Gates Level 25, 525 Collins Street Melbourne, VIC, 3000, Australia Principal Place of Business 10355 Science Center Drive Suite 210 San Diego, CA, 92121, USA Share Registry Boardroom Pty Limited Level 12, 225 George Street Sydney, NSW, 2000, Australia Auditor RSM Australia Partners Level 21, 55 Collins St Melbourne, VIC, 3000, Australia Australian Legal Advisor K&L Gates Level 25, 525 Collins Street Melbourne, VIC, 3000, Australia United States Legal Advisor The Grafe Law Office, PC PO Box 2689 Corrales, NM, 87048, USA Stock Exchange Imagion Biosystems Limited's shares are listed on the Australian Stock Exchange (ASX ticker: IBX) 63 About Imagion Biosystems Imagion Biosystems is developing a new non-radioactive and safe diagnostic imaging technology. Combining biotechnology and nanotechnology the Company aims to detect cancer and other diseases earlier and with higher specificity than is currently possible. Imagion Biosystems listed on the Australian Securities Exchange (ASX) in June 2017. www.imagionbiosystems.com investor@imagionbio.com +1 (855) 564-5264 Registered address: Level 25, 525 Collins Street, Melbourne, Victoria, 3000 Australia

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