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IQVIA

iqv · NYSE Healthcare
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FY2017 Annual Report · IQVIA
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UNITED STATES 
SECURITIES AND EXCHANGE COMMISSION 
Washington, D.C. 20549 

FORM 10-K 

(Mark One) 
☒

ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 

☐

TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 

For the fiscal year ended December 31, 2017 
or 

For the transition period from                     to                      . 
Commission File Number: 001-35907 

IQVIA HOLDINGS INC. 

(Exact name of registrant as specified in its charter)

Delaware
(State or other jurisdiction of 
incorporation or organization)

27-1341991
(I.R.S. Employer 
Identification Number)

4820 Emperor Blvd., Durham, North Carolina 27703 
and 
83 Wooster Heights Road, Danbury, Connecticut 06810 
(Address of principal executive offices and Zip Code) 
(919) 998-2000 and (203) 448-4600 
(Registrant’s telephone number, including area code) 

Securities registered pursuant to Section 12(b) of the Act: 

Title of Each Class:

Common Stock, par value $0.01 per share

Name of Each Exchange on which Registered

New York Stock Exchange

Securities registered pursuant to Section 12(g) of the Act: None 

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act.    Yes  ☒    No  ☐ 
Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or section 15(d) of the Exchange Act.    Yes  ☐    No  ☒ 
Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 

during the preceding twelve months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements 
for the past 90 days.    Yes  ☒    No  ☐ 

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to 

be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit 
and post such files).    Yes  ☒    No  ☐ 

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of 

registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K.    ☒ 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or 
emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 
12b-2 of the Exchange Act. 
Large accelerated filer

Accelerated filer

☐

☒  

Non-accelerated filer

☐(Do not check if a smaller reporting company)

Smaller reporting company

Emerging growth company

☐

☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or 

revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.  ☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).    Yes  ☐    No  ☒ 
The aggregate market value of the voting and non-voting common stock held by non-affiliates of the registrant, based upon the closing sale price as reported 

on the New York Stock Exchange on June 30, 2017, the last business day of the registrant’s most recently completed second quarter, was approximately 
$12,189,011,444. 

Indicate the number of shares outstanding of each of the issuer’s classes of Common Stock, as of the latest practicable date. 

Class

Number of Shares Outstanding

Common Stock $0.01 par value

208,251,468 shares outstanding as of February 12, 2018

Portions of the registrant’s Proxy Statement for the 2018 Annual Meeting of Stockholders are incorporated herein by reference in Part III of this Annual 

Report on Form 10-K to the extent stated herein. Such proxy statement will be filed with the Securities and Exchange Commission within 120 days of the registrant’s 
fiscal year ended December 31, 2017. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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IQVIA HOLDINGS INC.
FORM 10-K 

TABLE OF CONTENTS 

PART I 

Item  

1.
Business
1A. Risk Factors
1B. Unresolved Staff Comments
2.
Properties
3.
Legal Proceedings
4. Mine Safety Disclosures

Selected Financial Data

PART II 
5. Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities
6.
7. Management’s Discussion and Analysis of Financial Condition and Results of Operations
7A. Quantitative and Qualitative Disclosures About Market Risk
8.
9.
9A. Controls and Procedures
9B. Other Information

Financial Statements and Supplementary Data
Changes in and Disagreements with Accountants on Accounting and Financial Disclosure

PART III 

Executive Compensation
Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters

10. Directors, Executive Officers and Corporate Governance
11.
12.
13. Certain Relationships and Related Transactions and Director Independence
14.

Principal Accountant Fees and Services

15.

Exhibits and Financial Statement Schedules

PART IV 

Exhibit Index 

16.

Form 10-K Summary

Signatures 

2

 
 
FORWARD-LOOKING STATEMENTS 

Except for any historical information contained herein, the matters discussed or incorporated by reference in this Annual 
Report on Form 10-K contains forward-looking statements within the meaning of the federal securities laws, including Section 27A of 
the Securities Act of 1933, as amended (“Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended (the 
“Exchange Act”). Such forward-looking statements reflect, among other things, our current expectations, our forecasts and our 
anticipated results of operations, all of which are subject to known and unknown risks, uncertainties and other factors that may cause 
our actual results, performance or achievements, market trends, or industry results to differ materially from those expressed or implied 
by such forward-looking statements. Therefore, any statements contained herein that are not statements of historical fact may be 
forward-looking statements and should be evaluated as such. Without limiting the foregoing, the words “anticipates,” “believes,” 
“estimates,” “expects,” “intends,” “may,” “plans,” “projects,” “should,” “targets,” “will” and the negative thereof and similar words 
and expressions are intended to identify forward-looking statements. These forward-looking statements are subject to a number of 
risks, uncertainties and assumptions, including those described in Part I, Item 1A, “Risk Factors.” If one or more of these risks or 
uncertainties materialize, or if underlying assumptions prove incorrect, our actual results may vary materially from those expected, 
estimated or projected or as otherwise suggested by the forward-looking statements that we make for a number of reasons. Given these 
uncertainties, users of the information included or incorporated by reference in this Form 10-K, including investors and prospective 
investors, are cautioned not to place undue reliance on such forward-looking statements. All forward-looking statements are made 
only as of the date hereof. We assume no obligation to update any such forward-looking information to reflect actual results or 
changes in the factors affecting such forward-looking information. 

GENERAL 

On October 3, 2016, Quintiles Transnational Holdings Inc. (“Quintiles”) completed its previously announced merger of equals 
transaction (the “Merger”) with IMS Health Holdings, Inc. (“IMS Health”). Pursuant to the terms of the merger agreement dated as of 
May 3, 2016 between Quintiles and IMS Health (the “Merger Agreement”), IMS Health was merged with and into Quintiles, and the 
separate corporate existence of IMS Health ceased, with Quintiles continuing as the surviving corporation. Immediately prior to the 
completion of the Merger, Quintiles reincorporated as a Delaware corporation. Quintiles changed its name to Quintiles IMS Holdings, 
Inc. At the effective time of the Merger, each issued and outstanding share of IMS Health common stock was automatically converted 
into 0.3840 of a share of the Company’s common stock. 

On November 6, 2017, IQVIA Holdings Inc. (the “Company”) filed a Certificate of Amendment to its Amended and Restated 

Certificate of Incorporation (the “Certificate of Amendment”) to effect a change of the Company’s name from “Quintiles IMS 
Holdings, Inc.” to “IQVIA Holdings Inc.,” effective as of November 6, 2017 (the “Name Change”). 

On November 15, 2017, shares of the Company commenced trading under an updated New York Stock Exchange ticker 

symbol, “IQV,” and a new CUSIP number, 46266C 105.

When we use the terms “IQVIA,” the “Company,” “we,” “us” or “our” in this Annual Report on Form 10-K, we mean IQVIA 

Holdings Inc. and its subsidiaries on a consolidated basis, unless we state or the context implies otherwise. 

INDUSTRY AND MARKET DATA 

This annual report on Form 10-K includes market data and forecasts with respect to the healthcare industry. In some cases, we 
rely on and refer to market data and certain industry forecasts that were obtained from third party surveys, market research, consultant 
surveys, publicly available information and industry publications and surveys that we believe to be reliable. However, we have not 
independently verified data from industry analyses and cannot guarantee their accuracy or completeness. We believe that data 
regarding the industry, market size and its market position and market share within such industry provide general guidance but are 
inherently imprecise. Other industry and market data included in this annual report are from IQVIA analyses and have been identified 
accordingly, including, for example, IQVIA Market Prognosis, which is a subscription-based service that provides five-year 
pharmaceutical market forecasts at the national, regional and global levels. We are a leading global information provider for the 
healthcare industry and we maintain databases, produce market analyses and deliver information to clients in the ordinary course of 
our business. Our information is widely referenced in the industry and used by governments, payers, academia, the life sciences 
industry, the financial community and others. Most of this information is available on a subscription basis. Other reports and 
information are available publicly through our IQVIA Institute for Healthcare Informatics (the “IQVIA Institute”). All such 
information is based upon our own market research, internal databases and published reports and has not been verified by any 
independent sources. Our estimates and assumptions involve risks and uncertainties and are subject to change based on various 
factors, including those discussed in the “Risk Factors” section. These and other factors could cause results to differ materially from 
those expressed in the estimates and assumptions. 

3

TRADEMARKS AND SERVICE MARKS 

All trademarks, trade names, product names, graphics and logos of QuintilesIMS, Quintiles, IMS Health or IQVIA contained 

herein are trademarks or registered trademarks of IQVIA Holdings Inc. or its subsidiaries, as applicable, in the United States and/or 
other countries. All other party trademarks, trade names, product names, graphics and logos contained herein are the property of their 
respective owners. The use or display of other parties’ trademarks, trade names, product names, graphics or logos is not intended to 
imply, and should not be construed to imply, a relationship with, or endorsement or sponsorship of IQVIA Inc. or its subsidiaries by 
such other party.

Solely for convenience, the trademarks, service marks and trade names referred to in this annual report are listed without the ®, 
(sm) and (TM) symbols, but we will assert, to the fullest extent under applicable law, our rights or the rights of the applicable licensors 
to these trademarks, service marks and trade names. We do not intend our use or display of other companies’ trademarks or service 
marks to imply an endorsement or sponsorship of us by such other companies. 

4

 
 
Item 1. Business 

Our Company 

PART I 

We are a leading global provider of information, innovative technology solutions and contract research services focused on 

helping healthcare clients find better solutions for patients. Formed through the Merger of IMS Health and Quintiles, we apply human 
data science – leveraging the analytic rigor and clarity of data science to the ever-expanding scope of human science – to enable 
companies to reimagine and develop new approaches to clinical development and commercialization, speed innovation, and accelerate 
improvements in healthcare outcomes. Powered by the IQVIA CORE™, we deliver unique and actionable insights at the intersection 
of large scale analytics, transformative technology and extensive domain expertise, as well as execution capabilities to help biotech, 
medical device, and pharmaceutical companies, medical researchers, government agencies, payers and other healthcare stakeholders 
tap into a deeper understanding of diseases, human behaviors and scientific advances, in an effort to advance their path toward cures. 
With more than 55,000 employees, we conduct operations in more than 100 countries.

We have one of the largest and most comprehensive collections of healthcare information in the world, which includes more 

than 530 million comprehensive, longitudinal, non-identified patient records spanning sales, prescription and promotional data, 
medical claims, electronic medical records and social media. Our scaled and growing data set contains approximately 30 petabytes of 
proprietary data sourced from more than 120,000 data suppliers and covering over 900,000 data feeds globally. Based on this data, we 
deliver information and insights on over 85% of the world’s pharmaceuticals, as measured by 2016 sales. We standardize, organize, 
structure and integrate this data by applying our sophisticated analytics and leveraging our global technology infrastructure. This helps 
our clients run their organizations more efficiently and make better decisions to improve their clinical, commercial and financial 
performance. The breadth of the intelligent, actionable information we provide is not comprehensively available from any other source 
and our scope of information would be difficult and costly for another party to replicate. 

We leverage our proprietary information assets to develop clinical and commercial capabilities with a talented healthcare-

focused workforce that enables us to grow our relationships with healthcare stakeholders throughout the life science’s value chain. 
This set of capabilities includes: 

•

• 

•

•

•

A leading healthcare-specific global IT infrastructure, representing what we believe is one of the largest and most 
sophisticated information technology infrastructures in healthcare. We receive over 70 billion healthcare records 
annually, our infrastructure then connects complex healthcare data while applying a wide range of privacy, security, 
operational, legal and contractual protections for data in response to local law, supplier requirements and industry 
leading practices;

Analytics-driven clinical development, which improves clinical trial design, site identification and patient recruitment 
by empowering therapeutic, scientific, and domain experts with expansive levels of information, including product 
level tracking in 90 markets, and information about treatments and outcomes on more than 530 million non-identified 
patients; 

Robust real-world insights ecosystem, with sophisticated retrospective database analytics, prospective real-world data 
collection technology platforms and scientific expertise, which enables us to address critical healthcare issues of cost, 
value and patient outcomes; 

A growing set of proprietary clinical and commercial applications, which helps our clients increase their clinical 
operations performance and supports their sales operations, sales management, multi-channel marketing and 
performance management; and 

A staff of more than 55,000 employees across the globe, including approximately 19,000 Commercial Services 
employees, approximately 29,000 Research & Development Solutions employees and approximately 7,000 Integrated 
Engagement Services employees. 

5

Our mission-critical relationships with our life science clients consist of four important decision-making processes related to 

their product portfolios: Research and Development, Pre-Launch, Launch and In-Market. We continue to develop software and 
services applications to further deepen our level of client integration by enabling our clients to enhance and/or automate many 
components of these key decision-making processes. 

• Market opportunity assessment

• Drug pricing optimization • Market access

• Commercial operations

•

Project management and clinical 
monitoring

• Launch readiness

• Health technology 

assessment

• Clinical trial support services

• Commercial planning

• Commercial readiness

•

•

Sales force effectiveness

Sales force alignment

•

Patient recruitment

• Brand positioning

•

Forecasting

• Multi-channel marketing

• Clinical trial laboratory services

• Message testing

• Resource allocation

• Client relationship 

management

•

Strategic clinical trial planning 
and design

•

Influence networks

• Contract sales force

• Lifecycle management

• Territory design

• Observational studies

•

Stakeholder engagement

We believe that a powerful component of our value proposition is the breadth and depth of intelligence we provide to help our 

clients address fundamental operational questions. 

User
Research & Development

Which study centers have the 
target patients?

Illustrative Questions
Are there enough patients for 
my clinical trial?

How long will trial 
enrollment take to hit target 
patient volumes?

How much should I pay my 
sales representative next 
month?

Which providers generate the 
highest return on 
representative visit?

Does my sales representative 
drive appropriate prescribing?

What share of patients is 
appropriately treated?

Which underserved patient 
populations will benefit most 
from my new drug?

Is my brand gaining market 
share quickly enough to hit 
revenue forecasts?

Sales

Marketing

Real-World 
Evidence/Pharmacovigilance

What is the likely impact of 
new therapies on costs and 
outcomes?

Are new therapies performing 
better against existing standards 
of care in real-world settings?

Does real-world data indicate 
adverse events not detected in 
clinical trials?

6

 
 
 
 
 
 
 
 
 
 
 
 
 
Our Market Opportunity 

We compete in a market of greater than $230 billion consisting of outsourced research and development, real-world evidence 

and connected health and technology enabled commercial operations markets for the life sciences companies and the broader 
healthcare industry. The following sets forth our estimates for the size of our principal markets: 

•

•

• 

Outsourced research and development: Biopharmaceutical spending on drug development totaled approximately 
$100 billion in 2017. Of that amount, we estimate that our addressable opportunity (clinical development spending 
excluding preclinical spending) was approximately $59 billion. The portion of this addressable opportunity that was 
outsourced in 2017, based on our estimates, was approximately $26 billion; 

Real-World Evidence and connected health: Total addressable market of approximately $80 billion based on 2017 
sales that consists of two relatively equal parts. First, the market for Real-World Evidence of approximately $40 billion 
includes traditionally defined analytic platforms and implementation, medical and scientific analytic services, 
observation studies and market access. Second, the market for connected healthcare of approximately $40 billion 
includes areas such as revenue cycle management, payer analytics and clinical decision support services; and 

Technology enabled commercial operations: Total addressable market of approximately $50 billion based on 2017 
sales that includes information, data warehousing, IT outsourcing, software applications and other services in the 
broader market for IT services. This addressable market also includes commercial services such as recruiting, training, 
deploying and managing global sales forces, channel management, patient engagement services, market access 
consulting, brand communication, advisory services, and health information analytics and technology consulting. 

In deriving estimates of the size of the various markets described above, we review third-party sources, which include 
estimates and forecasts of spending in various segments, in combination with internal IQVIA research and analysis informed by our 
experience serving these segments, as well as projected growth rates for each of these segments. See “Industry and Market Data” 
above.   

We believe there are six key trends affecting our end markets that will create increasing demand for research and development 

services and commercial solutions: 

Growth and innovation in the life sciences industry. The life sciences industry is a large and critical part of the global 
healthcare system, and, according to the latest information available from the IQVIA Market Prognosis service, is estimated to have 
generated approximately $1.1 trillion in revenue in 2017. According to our research, revenue growth in the life sciences industry 
globally is expected to range from 3% to 6% between 2018 and 2022. According to the IQVIA Institute, it is estimated that spending 
on pharmaceuticals in emerging markets will expand at a 6% to 9% compound annual growth rate (“CAGR”) through 2022. The 
growth of emerging markets is making these geographies strategically important to life sciences organizations and, consistent with 
their approach in the developed markets, we expect these organizations to apply a high degree of sophistication to their commercial 
operations in these countries. For global companies, this requires highly localized knowledge and information assets, the development 
of market access strategies and performance benchmarking. In addition, local players are learning that they need to compete on the 
basis of improved information and analytics. 

Growth in Research and Development. Spending trends in research and development are impacted as a result of several 

factors, including major biopharmaceutical companies’ efforts to replenish revenues lost from the so-called “patent cliff,” increased 
access to capital by the small and midcap biotechnology industry, and recent increases in pharmaceutical approvals by regulatory 
authorities. The IQVIA Institute also estimates that approximately 225 new molecular entities (“NMEs”) are expected to be approved 
between 2018 and 2022, compared to 208 between 2012 and 2016, and 149 between 2007 and 2011. We believe that further research 
and development spending, combined with the continued need for cost efficiency across the healthcare landscape, will continue to 
create opportunities for biopharmaceutical services companies, particularly those with a global reach and broad service offerings, to 
help biopharmaceutical companies with their pre- and post-launch solutions development and commercialization needs. 

Increased Complexity in Research and Development. Biopharmaceutical companies face environments in which it has 

become increasingly difficult to operate. Improved standards of care in many therapeutic areas and the emergence of new types of 
therapies, such as biologics, genetically targeted therapies, gene and stem cell therapies, and other treatment modalities have led to 
more complex development and regulatory pathways. For example, the United States and European countries have recently released 
guidelines for the development of “biosimilar” products. We believe that our global clinical development capabilities, including our 
expertise in biomarkers and genomics and our global laboratory network, position us well to help biopharmaceutical companies 
manage the complexities inherent in an environment where this type of expertise is important. 

7

Regulators require clinical trials involving local populations as part of the process for approving new pharmaceutical products, 
especially in certain Asian and emerging markets. Understanding the epidemiological and physiological differences in different ethnic 
populations and being able to conduct clinical trials locally in certain geographies will be important to pharmaceutical product growth 
strategies, both for multinational and local/regional biopharmaceutical companies. We believe that our global clinical development 
capabilities and unmatched presence in Asia and other emerging markets make us a strong partner for biopharmaceutical companies 
managing the complexities of international drug development. 

Financial pressures driving the need for increased efficiency. Despite expected accelerating growth in the global life 
sciences market, we believe our clients will face increased operating margin pressure due to their changing product mix, pricing and 
reimbursement challenges, and rising costs of compliance. Product portfolios for life sciences companies have shifted toward specialty 
products with lower peak market sales potential than traditional primary care medicines. We believe that the need for 
biopharmaceutical companies to maximize productivity and lower costs across their processes from research and development through 
commercial operations will cause them to look to partners as they enter into outsourcing arrangements to improve efficiency. Further, 
our clients are looking for new ways to simplify processes and drive operational efficiencies by using automation, consolidating 
vendors and adopting new technology options such as hosted and cloud-based applications. This provides opportunities for technology 
services vendors to capture and consolidate internal spending by providing lower-cost and variable-cost options that lower clients’ 
research and development, selling, marketing and administrative costs. 

Evolving need to integrate and structure expanding sources of data. Over the past decade, many health systems around the 

world have focused on digitizing medical records. While such records theoretically enhance access to data, relevant information is 
often unintegrated, unstructured, siloed in disparate software systems, or entered inconsistently. In addition, new sources of data from 
the internet, such as social media and information on limited patient pools, and information resulting from enhanced diagnostic 
technologies are creating new sources of healthcare data. 

In order to derive valuable insights from existing and expanding sources of information, clients need access to statistically 

significant data sets organized into databases that can be queried and analyzed. For example, real-world evidence studies demonstrate 
practical and clinical efficacies, which we believe require the aggregation and integration of large clinical data sets across all care 
settings, types of therapies and patient cohorts. Longitudinal studies require analysis of non-identified patient diagnoses, treatments, 
procedures and laboratory test results to identify types of patients that will likely best respond to particular therapies. Finally, 
manufacturers also require the ability to analyze social media activity to identify unmet patient needs and support for new orphan 
drugs. This information is highly relevant to all healthcare stakeholders and we believe the opportunity to more broadly apply 
healthcare data can only be realized through structuring, organizing and integrating new and existing forms of data in conjunction with 
sophisticated analytics. 

Need for demonstrated value in healthcare. Participants in the healthcare industry are focused on improving quality and 

reducing costs, both of which require assessment of quality and value of therapies and providers. As a result, physicians no longer 
make prescribing decisions in isolation, but rather in the context of guidance and rules from payers, integrated delivery networks and 
governments. We believe life sciences companies are working to bring alignment across constituents on the value of their treatments 
in order to successfully develop and commercialize new therapies. 

There is increasing pressure on life sciences companies to support and justify the value of their therapies. Many new drugs that 
are being approved are more expensive than existing therapies, and will likely receive heightened scrutiny by regulators and payers to 
determine whether the existing treatment options would be sufficient. Additionally, many new specialty drugs are molecular-based 
therapies and require a more detailed understanding of clinical factors and influencers that demonstrate therapeutic value. As a result, 
leading life sciences companies are utilizing more sophisticated outcome research and data analytics services. 

We believe we are well positioned to take advantage of these global trends in healthcare. Beyond our proprietary information 

assets, we have developed key capabilities to assess opportunities to develop and commercialize therapies, support and defend the 
value of medicines and help our clients operate more efficiently through the application of insight-driven decision-making and cost-
efficient technology solutions. 

8

Our Growth Strategy 

We believe we are well positioned for continued growth across the markets we serve. Our strategy for achieving growth 

includes: 

Continue to innovate by leveraging our information, advanced analytics, technology and domain expertise. As a leader in 

the development and commercialization of new pharmaceutical therapies, we can empower our therapeutic, scientific and domain 
experts with expansive levels of information including product level tracking in 90 markets and information about treatments and 
outcomes on more than 530 million non-identified patients. Further, we have the ability to optimize the clinical trial process and 
enable our clients to reduce costs and get their products to market more quickly by running their clinical trials more efficiently and 
effectively through more informed site selection and faster patient recruitment practices. 

Build upon our extensive client relationships. We have a diversified base of over 8,000 clients in over 100 countries, and 
have expanded our client value proposition to address a broader market for research and development and commercial operations 
which we estimate to be more than $230 billion in 2017. Through the combined offerings of research and development and 
commercial services we built a platform that allows us to be a more complete partner to our clients. 

Expand portfolio through strategic acquisitions. We have and expect to continue to acquire assets and businesses that 
strengthen our value proposition to clients. We have developed an internal capability to source, evaluate and integrate acquisitions that 
have created value for stockholders. As the global healthcare landscape evolves, we expect that there will be a growing number of 
acquisition opportunities across the life sciences, payer and provider sectors. We expect to continue to invest in or explore 
opportunities for strategic acquisitions to grow our platform and enhance our ability to provide more services to our clients. 

Expand the penetration of our offerings to the broader healthcare marketplace. We believe that substantial opportunities 

exist to expand penetration of our market and further integrate our offerings in a broader cross-section of the healthcare marketplace, 
particularly connected healthcare. 

Our Offerings 

We offer hundreds of distinct services, applications and solutions to help our clients make critical decisions and perform better. 

We have three operating segments: Commercial Solutions, Research & Development Solutions and Integrated Engagement Services. 
Their offerings complement each other and can provide enhanced value to our clients when delivered together, with each driving 
demand for the other. 

For financial information regarding our segments, see Part II, Item 7 “Management’s Discussion and Analysis of Financial 

Condition and Results of Operations—Consolidated Results of Operations-Segment Results of Operations and Note 22 to our audited 
consolidated financial statements included elsewhere in this Annual Report on Form 10-K. 

Please refer to Note 21 to our audited consolidated financial statements included elsewhere in this Annual Report on Form 10-
K for further details regarding our foreign and domestic operations in 2017, 2016 and 2015. For a discussion of risks attendant to our 
foreign operations, see “Risk Factors — Our business is subject to international economic, political and other risks that could 
negatively affect our results of operations and financial condition.” 

Our Commercial Solutions offerings include: 

Technology solutions. We provide an extensive range of cloud-based applications and associated implementation services. 

Software as a Service (“SaaS”) solutions that support a wide range of clinical and commercial processes, including clinical trial design 
and planning, site start-up, patient consent, site payments, content management, multi-channel marketing, customer relationship 
management (“CRM”), performance management, incentive compensation, territory alignment, roster management, call planning, 
compliance reporting and master data management. These solutions are used by healthcare companies to manage, optimize and 
execute their clinical and commercial strategies in an orchestrated manner while addressing their regulatory obligations. Using 
proprietary algorithms, we combine our country-level data, healthcare expertise and therapeutic knowledge in over 100 countries to 
create our Global Market Insight family of offerings such as MIDAS, Analytics Link and Disease Insights, which provides a leading 
source of insight into international market dynamics and are used by most large pharmaceutical companies.

9

Real-World Insights. We enable clients to use non-identified patient-level data to understand treatments, outcomes, and costs 

to inform and advance healthcare decision making. With patient privacy and security safeguards, we offer data assets that integrate 
medical claims, prescriptions, electronic medical records, biomarkers and government statistics as needed for research requirements. 
Our proprietary technologies and advanced analytic skills enable us to help payer, government, and biopharmaceutical clients manage 
and use this information to understand the effectiveness and economic efficiency of drugs in real-world use.

Workflow analytics and consulting services. We provide a broad set of strategic and implementation consulting services, 

including advanced analytics and commercial processes outsourcing services to help the commercial operations of life sciences 
companies successfully transform their commercial models, engage more effectively with the healthcare stakeholders and reduce their 
operating costs. We also help our client’s R&D function to address strategic challenges in the drug development process. Our global 
teams leverage local market knowledge, deep scientific and therapeutic area expertise and our global information resources to assist 
our clients with R&D strategy, portfolio, brand and commercial strategy, as well as pricing and market access and launch excellence.

National information offerings. Our national offerings comprise unique services in 90 countries that provide consistent 
country level performance metrics related to sales of pharmaceutical products, prescribing trends, medical treatment and promotional 
activity across multiple channels including retail, hospital and mail order. These solutions are an integral part of critical processes in 
life science companies around the world and are also used extensively by the investment and financial sectors that deal with life 
science companies. 

Sub-national information offerings. Our sub-national offerings comprise unique services in more than 70 countries that 

provide a consistent measurement of sales or prescribing activity at the regional, zip code and individual prescriber level (depending 
on regulation in the relevant country). These solutions are used extensively, with a majority of pharmaceutical sales organizations 
within these countries dependent on these services to set goals, determine resourcing, measure performance and calculate 
compensation.  

Reference information offerings. Our widely used reference database that tracks more than 15 million healthcare 
professionals in approximately 100 countries, providing a comprehensive view of health care practitioners that is critical for the 
commercial success of our clients’ marketing and sales initiatives. 

Our Research & Development Solutions (“RDS”) offerings include: 

Project Management and Clinical Monitoring. Drawing upon our years of experience, our site databases, our site 
relationships and our highly trained staff, Clinical Solutions & Services enables the efficient conduct and coordination of multi-site 
clinical trials (generally Phase II-IV). Clinical Solutions & Services’ service offerings include protocol design, feasibility and 
operational planning, site start up and patient recruitment. 

Clinical Trial Support Services. Each clinical trial requires a number of concurrent services and data streams. We offer a 

broad range of functional services and consultation to support clinical trials through specialized expertise that help clients efficiently 
collect, analyze and report the quality data and evidence they need to gain regulatory approval. 

Q2 Solutions. We provide our clients globally scaled end-to-end clinical trial laboratory and research services through our 

majority-owned joint venture with Quest Diagnostics Incorporated (“Quest”) which was formed on July 1, 2015. We offer genomic 
and bioanalytical laboratory services supporting clinical trials offerings within the joint venture, which is referred to as Q2 Solutions. 

Strategic Planning and Design. Through our strategic planning and design services, we offer consultation services to improve 

decisions and performance including portfolio, program and protocol planning and design, biomarker consultation, benefit-risk 
management, regulatory affairs, biostatistics, modeling and simulation, and personalized medicine. 

10

Our principal Integrated Engagement Services (“IES”) offerings include: 

Health Care Provider Engagement Services. We partner with biopharmaceutical companies and other life sciences providers 

(e.g., medical device companies) to develop and deploy tailored stakeholder engagement solutions, including contract sales and 
market access professionals, which are focused on improving brand value at all stages of the product lifecycle from initial market 
entry to brands nearing patent expiry. 

Patient Engagement Services. Our nurse-based programs directly engage with patients to help improve their disease and 

medication understanding through interventional and non-interventional support, while also providing assistance in navigating 
complex reimbursement coverage issues. Our patient engagement services combine insight from clinical trials and social listening, 
behavioral design, personal and innovative eHealth multichannel interactions across multiple sites (e.g., the physician’s office, 
hospital, pharmacy, home), that act as an extension of the Health Care Provider prescribed treatment course which can lead to 
improved adherence and better overall outcomes. 

Medical Affairs Services. We provide a range of scientific strategy and medical affairs services to help biopharmaceutical 

companies plan and transition from the clinical trial setting to commercialization. Beginning in the clinical trial stage, our services can 
deploy educators to clinical trial sites to accelerate patient recruitment and improve retention, assist in translation of complex clinical 
trial data into a compelling scientific platform and publication strategy, and, provide field medical teams to facilitate scientific 
engagement with key opinion leaders and healthcare decision makers, before and after product approval. 

Our Clients 

Sales to companies in life sciences, including pharmaceutical companies, biotechnology companies, device and diagnostic 

companies, and consumer health companies, accounted for the majority of our revenues. Nearly all of the top 100 global 
pharmaceutical and biotechnology companies, measured by revenue, are clients, and many of these companies subscribe to reports and 
services in many countries. Other clients include payers, government and regulatory agencies, providers, pharmaceutical distributors, 
and pharmacies. Our client base is broad in scope and enables us to avoid dependence on any single client. No single client accounted 
for 10% or more of our combined company revenues in 2017, 2016 or 2015. 

Our Competition 

Our Commercial Solutions business competes with a broad and diverse set of businesses. While we believe no competitor 

provides the combination of geographical reach and breadth of its services, we generally compete in the countries in which we operate 
with other information, analytics, technology, services and consulting companies, as well as with the in-house capabilities of our 
clients. Also, we compete with certain government agencies, private payers and other healthcare stakeholders that provide their data 
directly to others. In addition to country-by-country competition, we have a number of regional and global competitors in the 
marketplace as well. Our offerings compete with various firms, including Accenture, Cognizant Technology Solutions, Covance, 
Deloitte, Evidera, GfK, LexisNexis Risk Solutions, IBM, Infosys, Kantar Health, McKinsey, Nielsen, OptumInsight, Parexel, Press 
Ganey, RTI Health Solutions, Symphony Health Solutions, Synovate Healthcare, The Advisory Board, Trizetto, Veeva, Verisk, and 
ZS Associates. We also compete with a broad range of new entrants and start-ups that are looking to bring new technologies and 
business models to healthcare information services and technology services. 

The markets for Research & Development Solutions offerings are highly competitive, and we compete against traditional 
contract research organizations (“CROs”), the in-house research and development departments of biopharmaceutical companies, 
universities and teaching hospitals. Among the traditional CROs, there are several-hundred small, limited-service providers, several 
medium-sized firms and only a few full-service companies with global capabilities. Our primary competitors include Covance Inc. 
(the drug development business of Laboratory Corporation of America Holdings), ICON plc, PAREXEL International Corporation, 
Pharmaceutical Product Development, Inc., PRA International, and Syneos Health, among others. 

Our Integrated Engagement Services business competes against the in-house sales and marketing departments of 

biopharmaceutical companies, other contract pharmaceutical sales and service organizations and consulting firms. Integrated 
Engagement Services’ primary competitor in the United States is Syneos Health. Outside of the United States, Integrated Engagement 
Services typically competes against single country or more regionally focused service providers, such as United Drug plc, Syneos 
Health, Publicis, EPS Corporation and CMIC HOLDINGS Co., Ltd. 

11

Government Regulation 

Many aspects of our businesses are regulated by federal and state laws, rules and regulations. Accordingly, we maintain a 

robust compliance program aimed at ensuring we operate our business in compliance with all existing legal requirements material to 
the operation of our businesses. There are, however, occasionally uncertainties involving the application of various legal requirements, 
the violation of which could result in, among other things, fines or other sanctions. See “Part I—Item 1A—Risk Factors” for 
additional detail. 

Good Clinical Practice 

Good Clinical Practice (“GCP”) regulations and guidelines are the industry standard for the conduct of clinical trials with 

respect to maintaining the integrity of the data and safety of the research subjects. The United States Food and Drug Administration 
(“FDA”), the European Medicines Agency (“EMA”), Japan’s Ministry of Health, Labour and Welfare and most other global 
regulatory authorities expect that study results and data submitted to such authorities be based on clinical trials conducted in 
accordance with GCP provisions. Records for clinical trials must be maintained for specified periods for inspection by the FDA and 
other regulators. 

Regulation of Drugs, Biologics and Medical Devices 

In the United States, pharmaceutical, biological and medical device products are subject to extensive regulation by the FDA. 

The Federal Food, Drug, and Cosmetic Act (“FDC Act”), the Public Health Service Act (“PHS Act”), and other federal and state 
statutes and regulations, govern, among other things, the research, development, testing, manufacture, storage, recordkeeping, 
approval, labeling, promotion and marketing, distribution, post-approval monitoring and reporting, sampling, and import and export of 
pharmaceutical, biological and medical device products. Failure to comply with applicable United States requirements may subject a 
company to a variety of administrative or judicial sanctions, such as FDA refusal to approve a pending new drug application (“NDA”) 
for a new drug, a biologics license application (“BLA”) for a new biological product pre-market approval (“PMA”) or clearance for a 
new medical device, warning or untitled letters, product recalls, product seizures, total or partial suspension of production or 
distribution, injunctions, fines, civil penalties, and criminal prosecution. 

Regulation of Patient Information 

Our information management services relate to the processing of information regarding patient diagnosis and treatment of 

disease and are, therefore, subject to substantial governmental regulation. In addition, the confidentiality of patient-specific 
information and the circumstances under which such patient-specific records may be released for inclusion in our databases or used in 
other aspects of our business is heavily regulated. Federal, state and foreign governments are contemplating or have proposed or 
adopted additional legislation governing the possession, use and dissemination of personal data, such as personal health information 
and personal financial data, as well as security breach notification rules for loss or theft of such data. Additional legislation or 
regulation of this type might, among other things, require us to implement additional security measures and processes or bring within 
the legislation or regulation de-identified health or other data, each of which may require substantial expenditures or limit our ability 
to offer some of our services. 

In particular, personal health information is recognized in many countries such as the United States, the European Union, or 

EU, and several countries in Asia, as a special, sensitive category of personal information, subject to additional mandatory protections. 
Violations of data protection regulations are subject to administrative penalties, civil money penalties and criminal prosecution, 
including corporate fines and personal liability. 

Regulation of Promotion, Marketing and Distribution of Pharmaceutical Products and Medical Devices 

Certain of our services are subject to detailed and comprehensive regulation in each geographic market in which we operate. 
Such regulation relates, among other things, to the distribution of drug samples, the marketing and promotion of approved products, 
the qualifications of sales representatives and the use of healthcare professionals in sales functions. 

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In the United States, certain of our services are subject to numerous federal and state laws pertaining to promotional activities 

involving pharmaceutical products and medical devices.  Certain of our services are subject to the FDA’s regulations against “off-
label promotion,” which require sales representatives to restrict promotion of the approved product they are detailing to the approved 
labeling for the product. The Prescription Drug Marketing Act imposes licensing, personnel record keeping, packaging, labeling, 
product handling and facility storage and security requirements. Other federal and state laws prohibit manufacturers, suppliers and 
providers from offering, giving or receiving kickbacks or other remuneration in connection with ordering or recommending the 
purchase or rental of healthcare items and services. The sale or distribution of pharmaceutical products and devices is also governed 
by the United States Federal Trade Commission Act and state consumer protection laws. We are subject to similar regulations 
currently in effect in the other countries where we offer Integrated Engagement Services. 

We are also subject to various laws and regulations that may apply to certain drug and device promotional practices, including, 

among others, various aspects of Medicare and federal healthcare programs. Violations of these laws and regulations may result in 
criminal and/or civil penalties, including possibly as an “aider and abettor.”  

Regulation of Laboratories 

Our United States “central” laboratories are subject to licensing and regulation under federal, state and local laws relating to 

hazard communication and employee right-to-know regulations, and the safety and health of laboratory employees. Additionally, our 
United States laboratories are subject to applicable federal and state laws and regulations and licensing requirements relating to the 
handling, storage and disposal of hazardous waste, radioactive materials and laboratory specimens, including the regulations of the 
Environmental Protection Agency, the Nuclear Regulatory Commission, the Department of Transportation, the National Fire 
Protection Agency and the United States Drug Enforcement Administration (“DEA”). The use of controlled substances in testing for 
drugs with a potential for abuse is regulated in the United States by the DEA and by similar regulatory bodies in other parts of the 
world. Our United States laboratories using controlled substances for testing purposes are licensed by the DEA. The regulations of the 
United States Department of Transportation, Public Health Service and Postal Service apply to the surface and air transportation of 
laboratory specimens. Our laboratories also are subject to International Air Transport Association regulations, which govern 
international shipments of laboratory specimens. Furthermore, when the materials are sent to a foreign country, the transportation of 
such materials becomes subject to the laws, rules and regulations of such foreign country. Our laboratories outside the United States 
are subject to applicable national laws governing matters such as licensing, the handling and disposal of medical specimens, hazardous 
waste and radioactive materials, as well as the health and safety of laboratory employees. 

In addition to its comprehensive regulation of safety in the workplace, the United States Occupational Safety and Health 

Administration has established extensive requirements relating to workplace safety for healthcare employers whose workers may be 
exposed to blood-borne pathogens such as HIV and the hepatitis B virus. Although we believe that we are currently in compliance in 
all material respects with such federal, state and local laws, failure to comply with such laws could subject us to denial of the right to 
conduct business, fines, criminal penalties and other enforcement actions. 

Further, laboratories that analyze human blood or other biological samples for the diagnosis and treatment of clinical trial 

subjects must comply with Clinical Laboratory Improvement Amendments (“CLIA”), as well as requirements established by various 
states. The failure to meet these requirements may result in civil penalties and suspension or revocation of the CLIA certification. 

Our Intellectual Property 

In addition to our proprietary data sets described above, we develop and use a number of proprietary methodologies, analytics, 

systems, technologies and other intellectual property in the conduct of our business. We rely upon a combination of legal, technical, 
and administrative safeguards to protect our proprietary and confidential information and trade secrets, and patent, copyright and 
trademark laws to protect other intellectual property rights. We consider our trademark and related names, marks and logos to be of 
material importance to our business, and we have registered or applied for registration for certain of these trademarks including 
IQVIA, QuintilesIMS, Quintiles, IMS Health and IMS, in the United States and other jurisdictions and aggressively seek to protect 
them. Trademarks and service marks generally may be renewed indefinitely so long as they are in use and/or their registrations are 
properly maintained, and so long as they have not been found to have become generic. The technology and other intellectual property 
rights owned and licensed by us are of importance to our business, although our management believes that our business, as a whole, is 
not dependent upon any one intellectual property or group of such properties.

Our Employees 

As of December 31, 2017, we have more than 55,000 employees worldwide. Almost all of these employees are full-time. None 
of our employees are covered by a collective bargaining agreement or are represented by a labor union. Employees in certain locations 
outside of the United States are represented by works councils as required by local laws. 

13

Available Information 

Our website address is www.iqvia.com, and our investor relations website is located at http://ir.iqvia.com. Information on our 
website is not incorporated by reference herein. Copies of our annual reports on Form 10-K, quarterly reports on Form 10-Q, current 
reports on Form 8-K and our Proxy Statements for our annual meetings of stockholders, and any amendments to those reports, as well 
as Section 16 reports filed by our insiders, are available free of charge on our website as soon as reasonably practicable after we file 
the reports with, or furnish the reports to, the Securities and Exchange Commission (“SEC”). Our SEC filings are also available for 
reading and copying at the SEC’s Public Reference Room at 100 F Street, NE, Washington, D.C. 20549. Information on the operation 
of the Public Reference Room may be obtained by calling the SEC at 1-800-SEC-0330. In addition, the SEC maintains an Internet site 
(http://www.sec.gov) containing reports, proxy and information statements, and other information regarding issuers that file 
electronically with the SEC. Information on the SEC’s website does not constitute part of this report. Also posted on our website are 
our certificate of incorporation and by-laws, the charters for our Audit Committee, Leadership Development and Compensation 
Committee and Nominating and Governance Committee, our Corporate Governance Guidelines, and our Code of Conduct governing 
our directors, officers and employees. Copies of our SEC reports and corporate governance information are available in print upon the 
request of any stockholder to our Investor Relations Department. Within the time period required by the SEC and the New York Stock 
Exchange (“NYSE”), we will post on our website any amendment to the Code of Business Conduct or the Code of Ethics for Chief 
Executive Officer and Senior Financial Officers or any waiver of either such policy applicable to any of our senior financial officers, 
executive officers or directors. 

14

 Item 1A. Risk Factors 

RISK FACTORS

We operate in a rapidly changing environment that involves a number of risks, some of which are beyond our control. You 
should consider carefully the risks and uncertainties described below together with the other information included in this Annual 
Report on Form 10-K, including our consolidated financial statements and related notes included elsewhere in this Annual Report on 
Form 10-K, in evaluating our company. The occurrence of any of the following risks may materially and adversely affect our business, 
financial condition, results of operations and future prospects. 

Risks Relating to Our Business 

The potential loss or delay of our large contracts or of multiple contracts could adversely affect our results. 

Most of our Research & Development Solutions clients can terminate our contracts upon 30 to 90 days notice. Our clients may 

delay, terminate or reduce the scope of our contracts for a variety of reasons beyond our control, including but not limited to: 

•

• 

• 

•

• 

• 

•

• 

•

• 

•

decisions to forego or terminate a particular clinical trial; 

lack of available financing, budgetary limits or changing priorities; 

actions by regulatory authorities; 

production problems resulting in shortages of the drug being tested; 

failure of products being tested to satisfy safety requirements or efficacy criteria; 

unexpected or undesired clinical results for products; 

insufficient patient enrollment in a clinical trial; 

insufficient investigator recruitment; 

shift of business to a competitor or internal resources; 

product withdrawal following market launch; or 

shut down of manufacturing facilities. 

As a result, contract terminations, delays and alterations are a regular part of our Research & Development Solutions business. 
In the event of termination, our contracts often provide for fees for winding down the project, but these fees may not be sufficient for 
us to maintain our margins, and termination may result in lower resource utilization rates. In addition, we will not realize the full 
benefits of our backlog of contractually committed services if our clients cancel, delay or reduce their commitments under our 
contracts with them, which may occur if, among other things, a client decides to shift its business to a competitor or revoke our status 
as a preferred provider. Thus, the loss or delay of a large contract or the loss or delay of multiple contracts could adversely affect our 
revenues and profitability. We believe the risk of loss or delay of multiple contracts potentially has greater effect where we are party 
to broader partnering arrangements with global biopharmaceutical companies. 

 We depend on third parties for data and support services. Our suppliers or providers might restrict our use of or refuse to 

license data or provide services, which could lead to our inability to access certain data or provide certain services and, as a result, 
materially and adversely affect our operating results and financial condition. 

Each of our Commercial Solutions information services is derived from data we collect from third parties. These data suppliers 

are numerous and diverse, reflecting the broad scope of information that we collect and use in our business. 

15

Although we typically enter into long-term contractual arrangements with many of these suppliers of data, at the time of entry 

into a new contract or renewal of an existing contract, suppliers may increase restrictions on our use of such data, increase the price 
they charge us for data or refuse altogether to license the data to us. In addition, during the term of any data supply contract, suppliers 
may fail to adhere to our data quality control standards or fail to deliver data. Further, although no single individual data supplier is 
material to our business, if a number of suppliers collectively representing a significant amount of data that we use for one or more of 
our services were to impose additional contractual restrictions on our use of or access to data, fail to adhere to our quality-control 
standards, repeatedly fail to deliver data or refuse to provide data, now or in the future, our ability to provide those services to our 
clients could be materially adversely impacted, which may harm our operating results and financial condition. 

Additionally, we depend on third parties for support services to our business. Such support services include, but are not limited 

to, third-party transportation providers, suppliers of drugs for patients participating in clinical trials, suppliers of kits for use in our 
clinical trial laboratories business, suppliers of reagents for use in our testing equipment and providers of maintenance contracts for 
our equipment. The failure of any of these third parties to adequately provide the critical support services could have a material 
adverse effect on our business. 

If we fail to perform our services in accordance with contractual requirements, regulatory standards and ethical 

considerations, we could be subject to significant costs or liability and our reputation could be harmed. 

We contract with biopharmaceutical companies to perform a wide range of services to assist them in bringing new drugs to 
market. Our services include monitoring clinical trials, data and laboratory analysis, electronic data capture, patient recruitment and 
other related services. Such services are complex and subject to contractual requirements, regulatory standards and ethical 
considerations. For example, we must adhere to regulatory requirements such as the FDA and current GCP, Good Laboratory Practice 
and Good Manufacturing Practice requirements. If we fail to perform our services in accordance with these requirements, regulatory 
agencies may take action against us for failure to comply with applicable regulations governing clinical trials or sales and marketing 
practices. Such actions may include sanctions, such as injunctions or failure of such regulatory authorities to grant marketing approval 
of products, delay, suspension or withdrawal of approvals, license revocation, product seizures or recalls, operational restrictions, civil 
or criminal penalties or prosecutions, damages or fines. Clients may also bring claims against us for breach of our contractual 
obligations and patients in the clinical trials and patients taking drugs approved on the basis of those clinical trials may bring personal 
injury claims against us for negligence. Any such action could have a material adverse effect on our results of operations, financial 
condition and reputation. 

Such consequences could arise if, among other things, the following occur: 

Improper performance of our services. The performance of clinical development services is complex and time-consuming. 

For example, we may make mistakes in conducting a clinical trial that could negatively impact or obviate the usefulness of the clinical 
trial or cause the results of the clinical trial to be reported improperly. If the clinical trial results are compromised, we could be subject 
to significant costs or liability, which could have an adverse impact on our ability to perform our services. As examples: 

•

•

non-compliance generally could result in the termination of ongoing clinical trials or sales and marketing projects or 
the disqualification of data for submission to regulatory authorities; 

compromise of data from a particular clinical trial, such as failure to verify that informed consent was obtained from 
patients, could require us to repeat the clinical trial under the terms of our contract at no further cost to our client, but at 
a substantial cost to us; and 

• 

breach of a contractual term could result in liability for damages or termination of the contract. 

Large clinical trials can cost up to hundreds of millions of dollars, and while we endeavor to contractually limit our exposure 

to such risks, improper performance of our services could have an adverse effect on our financial condition, damage our reputation 
and result in the cancellation of current contracts by or failure to obtain future contracts from the affected client or other clients. 

Investigation of clients. From time to time, one or more of our clients are audited or investigated by regulatory authorities or 
enforcement agencies with respect to regulatory compliance of their clinical trials, programs or the marketing and sale of their drugs. 
In these situations, we have often provided services to our clients with respect to the clinical trials, programs or activities being 
audited or investigated, and we are called upon to respond to requests for information by the authorities and agencies. There is a risk 
that either our clients or regulatory authorities could claim that we performed our services improperly or that we are responsible for 
clinical trial or program compliance. If our clients or regulatory authorities make such claims against us and prove them, we could be 
subject to damages, fines or penalties. In addition, negative publicity regarding regulatory compliance of our clients’ clinical trials, 
programs or drugs could have an adverse effect on our business and reputation. 

16

Insufficient client funding to complete a clinical trial. As noted above, clinical trials can cost hundreds of millions of dollars. 
There is a risk that we may initiate a clinical trial for a client, and then the client becomes unwilling or unable to fund the completion 
of the clinical trial. In such a situation, notwithstanding the client’s ability or willingness to pay for or otherwise facilitate the 
completion of the clinical trial, we may be ethically bound to complete or wind down the clinical trial at our own expense. 

Security breaches and unauthorized use of our IT systems and information, or the IT systems or information in the 

possession of our vendors, could expose us, our clients, our data suppliers or others to risk of loss. 

We rely upon the security of our computer and communications systems infrastructure to protect us from cyberattacks and 
unauthorized access. Cyberattacks can include malware, computer viruses, hacking or other significant disruption of our computer, 
communications and related systems. Cyber threats are rapidly evolving and are becoming increasingly sophisticated. Despite our 
efforts to ensure the integrity of our systems, as cyber threats evolve and become more difficult to detect and successfully defend 
against, one or more cyber threats might defeat the measures that we or our vendors take to anticipate, detect, avoid or mitigate such 
threats. Certain techniques used to obtain unauthorized access, introduce malicious software, disable or degrade service, or sabotage 
systems may be designed to remain dormant until a triggering event and we may be unable to anticipate these techniques or implement 
adequate preventative measures since techniques change frequently or are not recognized until launched, and because cyberattacks can 
originate from a wide variety of sources. Although we take steps to manage and avoid these risks and to prevent their recurrence, our 
preventive and remedial actions may not be successful. Such attacks, whether successful or unsuccessful, could result in our incurring 
costs related to, for example, rebuilding internal systems, defending against litigation, responding to regulatory inquiries or actions, 
paying damages or fines, or taking other remedial steps with respect to third parties. Publicity about vulnerabilities and attempted or 
successful incursions could damage our reputation with clients and data suppliers and reduce demand for our services. 

We also store proprietary and sensitive information in connection with our business, which could be compromised by a 
cyberattack. To the extent that any disruption or security breach results in a loss or damage to our data, an inappropriate disclosure of 
proprietary or sensitive information, an inability to access data sources, or an inability to process data or provide our offerings to our 
clients, it could cause significant damage to our reputation, affect our relationships with our data suppliers and clients (including loss 
of suppliers and clients), lead to claims against us and ultimately harm our business. We may be required to incur significant costs to 
alleviate, remedy or protect against damage caused by these disruptions or security breaches in the future. We may also face inquiry or 
increased scrutiny from government agencies as a result of any such disruption or breach. While we have insurance coverage for 
certain instances of a cyber security breach, our coverage may not be sufficient if we suffer a significant attack or multiple attacks. 
Any such breach or disruption could have a material adverse effect on our operating results and our reputation as a provider of 
mission-critical services. 

Some of our vendors have significant responsibility for the security of certain of our data centers and computer-based 
platforms. Also, our data suppliers have responsibility for security of their own computer and communications environments. These 
third parties face risks relating to cyber security similar to ours, which could disrupt their businesses and therefore materially impact 
ours. Accordingly, we are subject to any flaw in or breaches to their computer and communications systems or those that they operate 
for us, which could result in a material adverse effect on our business, operations and financial results. 

Failure to meet productivity objectives under our internal business transformation initiatives could adversely impact our 

competitiveness and harm our operating results. 

We are pursuing business transformation initiatives to update technology, increase innovation and obtain operating 
efficiencies. As part of these initiatives, we seek to improve our productivity, flexibility, quality, functionality and cost savings by 
investing in the development and implementation of global platforms and integration of our business processes and functions to 
achieve economies of scale. For example, we are moving local standardizing and cleaning from countries around the world to Asia, 
and retiring local standardizing and cleaning systems. These various initiatives may not yield their intended gains, which may impact 
our competitiveness and our ability to meet our growth objectives and, as a result, materially and adversely affect our business, 
operating results and financial condition. 

17

If we are unsuccessful at investing in growth opportunities, our business could be materially and adversely affected. 

We continue to invest significantly in growth opportunities, including the development and acquisition of new data, 
technologies and services to meet our clients’ needs. For example, we are expanding our services and technology offerings, such as 
the development of a cloud-based platform with a growing number of applications to support commercial operations for life sciences 
companies (e.g., multi-channel marketing, marketing campaign management, customer relationship management, incentive 
compensation management, targeting and segmentation, performance management and other applications). We also continue to invest 
significantly in growth opportunities in emerging markets, such as the development, launch and enhancement of services in China, 
India, Russia, Turkey and other countries. We believe healthcare spending in these emerging markets will continue to grow over the 
next five years, and we consider our presence in these markets to be an important focus of our growth strategy. 

There is no assurance that our investment plans or growth strategy will be successful or will produce a sufficient or any return 
on our investments. Further, if we are unable to develop new technologies and services, clients do not purchase our new technologies 
and services, our new technologies and services do not work as intended or there are delays in the availability or adoption of our new 
technologies and services, then we may not be able to grow our business or growth may occur slower than anticipated. Additionally, 
although we expect continued growth in healthcare spending in emerging markets, such spending may occur more slowly or not at all, 
and we may not benefit from our investments in these markets.

 We plan to fund growth opportunities with cash from operations or from future financings. There can be no assurance that 

those sources will be available in sufficient amounts to fund future growth opportunities when needed. 

Any of the foregoing could have a material and adverse effect on our operating results and financial condition. 

Data protection, privacy and similar laws in the United States and around the world restrict access, use and disclosure of 

personal information, and failure to comply with or adapt to changes in these laws could materially and adversely harm our 
business. 

The confidentiality, collection, use and disclosure of personal data, including individually identifiable health information and 
clinical trial patient-specific information, are subject to governmental regulation generally in the country that the personal data were 
collected or used. For example, United States federal regulations under the Health Insurance Portability and Accountability Act of 
1996 (“HIPAA”) create specific requirements for the protection of the privacy and security of individual health information. These 
provisions apply to both “covered entities” (primarily health care providers and health insurers) and their “business associates” or 
service providers.  As there are some instances where we are a HIPAA “business associate” of a “covered entity,” we can be directly 
liable for mishandling protected health information. Under HIPAA’s enforcement scheme, we can be subject to significant penalties in 
connection with HIPAA violations, along with the potential for significant other expenditures related to these activities. These rules 
require individuals’ written authorization in many situations, in addition to any required informed consent, before protected health 
information may be used for research. We are both directly and indirectly affected by the privacy provisions surrounding individual 
authorizations because many investigators with whom we are involved in clinical trials are directly subject to them as a HIPAA 
“covered entity” and because we obtain identifiable health information from third parties that are subject to such regulations. The laws 
and regulations related to the protection of personal health information in connection with research activities are under re-evaluation, 
particularly in the United States, and changes to these regulations could have a material adverse impact on our ability to provide some 
of our services in their current form or maintain our profitability. In general, patient health information is among the most sensitive 
(and highly regulated) of personal information and laws and regulations around the United States and the world are designed to ensure 
that information about an individual’s healthcare is properly protected from inappropriate access, use and disclosure. Laws restricting 
access, use and disclosure of patient health information also include the European Union’s (“EU”) General Data Protection 
Regulation, Canada’s Personal Information Protection and Electronic Documents Act and other data protection, privacy, data security 
and similar national, state/provincial and local laws. In the EU personal data includes any information that relates to an identified or 
identifiable natural person with health information carrying additional obligations, including obtaining the explicit consent from the 
individual for collection, use or disclosure of the information. In addition, we are subject to EU rules with respect to cross-border 
transfers of such data out of the EU (along with similar data transfer requirements in other countries). The United States, the EU and 
its member states, and other countries where we have operations, such as Japan, South Korea, Malaysia, the Philippines, Russia and 
Singapore, continue to issue new privacy and data protection rules and regulations that relate to personal data and health information.

18

We have established frameworks, models, processes and technologies to manage privacy and security for many data types, 

from a variety of sources, and under myriad privacy and data protection laws worldwide. In addition, we rely on our data suppliers to 
deliver information to us in a form and in a manner that complies with applicable privacy and data protection laws. These laws are 
complex and there is no assurance that the safeguards and controls employed by us or our data suppliers will be sufficient to prevent a 
breach of these laws, or that claims will not be filed against us or our data suppliers despite such safeguards and controls. Failure to 
comply with such laws, certain certification/registration and annual re-certification/registration provisions associated with these data 
protection and privacy regulations, and similar rules in various jurisdictions, or to resolve any serious privacy complaints, may result 
in, among other things, regulatory sanctions, criminal prosecution, civil liability, negative publicity, damage to our reputation, or data 
being blocked from use or liability under contractual provisions. For example, in July 2015, indictments were issued by the Seoul 
Central District Prosecutors’ Office in South Korea against IMS Korea and two of its employees, among others, alleging improper 
handling of sensitive health information in violation of applicable privacy laws. See Item 3 “Legal Proceedings” for additional 
information.

Laws and expectations relating to privacy continue to evolve, and we continue to adapt to changing needs. For example, the 

definition of “personally identifiable information” and “personal data” continues to evolve and broaden and many new laws and 
regulations are being enacted. In addition, certain long-established programs have been (or are at risk of being) declared invalid (such 
as the EU-U.S. Safe Harbor framework that operated for many years but was struck down by European courts in 2015), so that this 
area remains in a state of flux. Changes to these programs may adversely impact our ability to provide services to our clients or 
develop new products or services. Federal, state and foreign governments are contemplating or have proposed or adopted additional 
legislation governing the collection, possession, use or dissemination of personal data, such as personal health information, and 
personal financial data as well as security breach notification rules for loss or theft of such data. Additional legislation or regulation of 
this type might, among other things, require us to implement new security measures and processes or bring within the legislation other 
personal data not currently regulated, each of which may require substantial expenditures or limit our ability to offer some of our 
services. Additionally, changes in these laws (including newly released interpretations of these laws by courts and regulatory bodies) 
may limit our data access, use and disclosure, and may require increased expenditures by us or may dictate that we not offer certain 
types of services. Any of the foregoing may have a material adverse impact on our ability to provide services to our clients or maintain 
our profitability.

There is ongoing concern from privacy advocates, regulators and others regarding data protection and privacy issues, and the 
number of jurisdictions with data protection and privacy laws has been increasing. Also, there are ongoing public policy discussions 
regarding whether the standards for de-identified, anonymous or pseudonymized health information are sufficient, and the risk of re-
identification sufficiently small, to adequately protect patient privacy. These discussions may lead to further restrictions on the use of 
such information. There can be no assurance that these initiatives or future initiatives will not adversely affect our ability to access and 
use data or to develop or market current or future services. 

Data protection, privacy and similar laws protect more than patient information, and although they vary by jurisdiction, these 

laws can extend to employee information, business contact information, provider information and other information relating to 
identifiable individuals. Failure to comply with these laws may result in, among other things, civil and criminal liability, negative 
publicity, damage to our reputation and liability under contractual provisions. In addition, compliance with such laws may require 
increased costs to us or may dictate that we not offer certain types of services. 

 The occurrence of any of the foregoing could impact our ability to provide the same level of service to our clients, require us 

to modify our offerings or increase our costs, which could materially and adversely affect our operating results and financial 
condition.

Our success depends on our ability to protect our intellectual property rights. 

Our success depends, in part, upon our ability to develop, use and protect our proprietary methodologies, analytics, systems, 

technologies and other intellectual property. Existing laws of the various countries in which we provide services or solutions offer 
only limited protection of our intellectual property rights, and the protection in some countries may be very limited. We rely upon a 
combination of trade secrets, confidentiality policies, nondisclosure, invention assignment and other contractual arrangements, and 
patent, copyright and trademark laws, to protect our intellectual property rights. These laws are subject to change at any time and 
certain agreements may not be fully enforceable, which could further restrict our ability to protect our innovations. Our intellectual 
property rights may not prevent competitors from independently developing services similar to or duplicative of ours. Further, the 
steps we take in this regard might not be adequate to prevent or deter infringement or other misappropriation of our intellectual 
property by competitors, former employees or other third parties, and we might not be able to detect unauthorized use of, or take 
appropriate and timely steps to enforce, our intellectual property rights. 

19

 Our ability to obtain, protect and enforce our intellectual property rights is subject to general litigation or third-party 
opposition risks, as well as the uncertainty as to the scope of protection, registrability, patentability, validity and enforceability of our 
intellectual property rights in each applicable country. Governments may adopt regulations, and government agencies or courts may 
render decisions, requiring compulsory licensing of intellectual property rights. When we seek to enforce our intellectual property 
rights we may be subject to claims that the intellectual property rights are invalid or unenforceable. Litigation may be necessary in the 
future to enforce our intellectual property rights and to protect our confidential and proprietary information. Litigation brought to 
protect and enforce our intellectual property rights could be costly, time consuming and distracting to management and could result in 
the impairment or loss of portions of our intellectual property rights. Furthermore, our efforts to enforce our intellectual property 
rights may be met with defenses, counterclaims and countersuits attacking the validity and enforceability of our intellectual property 
rights. Our inability to protect our proprietary technology against unauthorized copying or use, as well as any costly litigation or 
diversion of our management’s attention and resources, could delay further sales or the implementation of our solutions, impair the 
functionality of our solutions, delay introductions of new solutions, result in our substituting inferior or more costly technologies into 
our solutions, or injure our reputation and harm our operating results and financial condition. 

Depending on the circumstances, we might need to grant a specific client greater rights in intellectual property developed in 
connection with a contract than we otherwise generally do. In certain situations, we might forego all rights to the use of intellectual 
property we create, which would limit our ability to reuse that intellectual property for other clients. Any limitation on our ability to 
provide a service or solution could cause us to lose revenue-generating opportunities and require us to incur additional expenses to 
develop or license new or modified solutions for future projects. 

The theft or unauthorized use or publication of our trade secrets and other confidential business information could reduce the 

differentiation of our services and harm our business; the value of our investment in development or business acquisitions could be 
reduced; and third parties might make claims against us related to losses of their confidential or proprietary information. In addition, 
we may not be able to discover or determine the extent of any unauthorized use of our proprietary rights. Third parties that license our 
proprietary rights also may take actions that diminish the value of our proprietary rights or reputation. The protection of our 
intellectual property may require the expenditure of significant financial and managerial resources. Moreover, the steps we take to 
protect our intellectual property may not adequately protect our rights or prevent third parties from infringing or misappropriating our 
proprietary rights. These incidents and claims could harm our business, reduce revenue, increase expenses and harm our reputation. 

We may be subject to claims by others that we are infringing on their intellectual property rights. 

Third parties may assert claims that we or our clients infringe their intellectual property rights and these claims, with or 

without merit, could be expensive to litigate, cause us to incur substantial costs and divert management resources and attention in 
defending the claim. In some jurisdictions, plaintiffs can also seek injunctive relief that may limit the operation of our business or 
prevent the marketing and selling of our services that infringe on the plaintiff’s intellectual property rights. To resolve these claims, 
we may enter into licensing agreements with restrictive terms or significant fees, stop selling, be required to implement costly 
redesigns to the affected services, or pay damages to satisfy contractual obligations to others. If we do not resolve these claims in 
advance of a trial, there is no guarantee that we will be successful in court. These outcomes may have a material adverse impact on our 
business, operating results and financial condition. 

In addition, certain contracts with our suppliers or clients contain provisions whereby we indemnify, subject to certain 
limitations, the counterparty for damages suffered as a result of claims related to intellectual property infringement and the use of our 
data. Claims made under these provisions could be expensive to litigate and could result in significant payments. 

 We rely on licenses from third parties to certain technology and intellectual property rights for some of our services and the 

licenses we currently have could terminate or expire. 

Some of our business services rely on technology or intellectual property rights owned and controlled by others. Our licenses 

to this technology or these intellectual property rights could be terminated or could expire. We may be unable to replace these licenses 
in a timely manner. Failure to renew these licenses, or renewals of these licenses on less advantageous terms, could harm our 
operating results and financial condition. 

20

Our financial results may be adversely affected if we underprice our contracts, overrun our cost estimates or fail to receive 

approval for or experience delays in documenting change orders. 

Most of our Research & Development Solutions contracts are either fee for service contracts or fixed-fee contracts. Our past 

financial results have been, and our future financial results may be, adversely impacted if we initially underprice our contracts or 
otherwise overrun our cost estimates and are unable to successfully negotiate a change order. Change orders typically occur when the 
scope of work we perform needs to be modified from that originally contemplated by our contract with the client. Modifications can 
occur, for example, when there is a change in a key clinical trial assumption or parameter or a significant change in timing. Where we 
are not successful in converting out-of-scope work into change orders under our current contracts, we bear the cost of the additional 
work. Such underpricing, significant cost overruns or delay in documentation of change orders could have a material adverse effect on 
our business, results of operations, financial condition or cash flows. 

The relationship of backlog to revenues varies over time. 

Backlog represents future revenues for our Research & Development Solutions business from work not yet completed or 

performed under signed binding commitments and signed contracts. Once work begins on a project, revenue is recognized over the 
duration of the project. Projects may be terminated or delayed by the client or delayed by regulatory authorities for reasons beyond our 
control. To the extent projects are delayed, the timing of our revenue could be affected. In the event that a client cancels a contract, we 
typically would be entitled to receive payment for all services performed up to the cancellation date and subsequent client-authorized 
services related to terminating the canceled project. Typically, however, we have no contractual right to the full amount of the revenue 
reflected in our backlog in the event of a contract cancellation. The duration of the projects included in our backlog, and the related 
revenue recognition, range from a few weeks to many years. Our backlog may not be indicative of our future revenues from our 
Research & Development Solutions business, and we may not realize all the anticipated future revenue reflected in our backlog. A 
number of factors may affect backlog, including: 

•

•

• 

•

the size, complexity and duration of the projects; 

the percentage of full services versus functional services; 

the cancellation or delay of projects; and 

change in the scope of work during the course of a project. 

Although an increase in backlog will generally result in an increase in revenues to be recognized over time (depending on the 

level of cancellations), an increase in backlog at a particular point in time does not necessarily correspond directly to an increase in 
revenues during a particular period. The extent to which contracts in backlog will result in revenue depends on many factors, including 
but not limited to delivery against projected schedules, the need for scope changes (change orders), contract cancellations and the 
nature, duration, size, complexity and phase of the contracts, each of which factors can vary significantly from time to time. 

The rate at which our backlog converts to revenue may vary over time for a variety of reasons. The revenue recognition on 

larger, more global projects could be slower than on smaller, less global projects for a variety of reasons, including but not limited to 
an extended period of negotiation between the time the project is awarded to us and the actual execution of the contract, as well as an 
increased timeframe for obtaining the necessary regulatory approvals. Additionally, the increased complexity of clinical trials and the 
need to enroll precise patient populations could extend the length of clinical trials causing revenue to be recognized over a longer 
period of time. Further, delayed projects will remain in backlog, unless otherwise canceled by the client, and will not generate revenue 
at the rate originally expected. Thus, the relationship of backlog to realized revenues may vary over time.

21

Our business depends on the continued effectiveness and availability of our information systems, including the information 

systems we use to provide our services to our clients, and failures of these systems may materially limit our operations. 

Due to the global nature of our business and our reliance on information systems to provide our services, we intend to increase 

our use of web-enabled and other integrated information systems in delivering our services. We also provide access to similar 
information systems to certain of our clients in connection with the services we provide them. As the breadth and complexity of our 
information systems continue to grow, we will increasingly be exposed to the risks inherent in the development, integration and 
ongoing operation of evolving information systems, including: 

• 

• 

• 

disruption, impairment or failure of data centers, telecommunications facilities or other key infrastructure platforms; 

security breaches of, cyberattacks on and other failures or malfunctions in our critical application systems or their 
associated hardware; and 

excessive costs, excessive delays or other deficiencies in systems development and deployment. 

The materialization of any of these risks may impede the processing of data, the delivery of databases and services, and the 

day-to-day management of our business and could result in the corruption, loss or unauthorized disclosure of proprietary, confidential 
or other data. While we have disaster recovery plans in place, they might not adequately protect us in the event of a system failure. 
While many of our operations have disaster recovery plans in place, we currently do not have excess or standby computer processing 
or network capacity everywhere in the world to avoid disruption in the receipt, processing and delivery of data in the event of a system 
failure. Despite any precautions we take, damage from fire, floods, hurricanes, power loss, telecommunications failures, computer 
viruses, break-ins and similar events at our various computer facilities could result in interruptions in the flow of data to our servers 
and from our servers to our clients. Corruption or loss of data may result in the need to repeat a clinical trial at no cost to the client, but 
at significant cost to us, the termination of a contract or damage to our reputation. 

In addition, any failure by our computer environment to provide sufficient processing or network capacity to transfer data 
could result in interruptions in our service. In the event of a delay in the delivery of data, we could be required to transfer our data 
collection operations to an alternative provider of server hosting services. Such a transfer could result in significant delays in our 
ability to deliver services to our clients, and increase our costs. Additionally, significant delays in system enhancements or inadequate 
performance of new or upgraded systems once completed could damage our reputation and harm our business. Finally, long-term 
disruptions in the infrastructure caused by events such as natural disasters, the outbreak of war, the escalation of hostilities and acts of 
terrorism, particularly involving cities in which we have offices, could adversely affect our businesses. Although we carry property 
and business interruption insurance, our coverage might not be adequate to compensate us for all losses that may occur. 

We have continued to undertake significant programs to optimize business processes with respect to our services. Our inability 

to effectively manage the implementation and adapt to new processes designed into new or upgraded systems in a timely and cost-
effective manner may result in disruption to our business and negatively affect our operations.  

We have entered into agreements with certain vendors to provide systems development and integration services that develop or 
license to us the IT platform for programs to optimize our business processes. If such vendors fail to perform as required or if there are 
substantial delays in developing, implementing and updating the IT platform, our client delivery may be impaired, and we may have to 
make substantial further investments, internally or with third parties, to achieve our objectives. Additionally, our progress may be 
limited by parties with existing or claimed patents who seek to enjoin us from using preferred technology or seek license payments 
from us. Meeting our objectives is dependent on a number of factors which may not take place as we anticipate, including obtaining 
adequate technology-enabled services, creating IT-enabled services that our clients will find desirable and implementing our business 
model with respect to these services. Also, increased IT-related expenditures may negatively impact our profitability. 

22

We may experience challenges with the acquisition, development, enhancement or deployment of technology necessary for 

our business. 

We operate in businesses that require sophisticated computer systems and software for data collection, data processing, cloud-

based platforms, analytics, cryptography, statistical projections and forecasting, mobile computing, social media analytics and other 
applications and technologies, particularly our Commercial Solutions business. We seek to address our technology risks by increasing 
our reliance on the use of innovations by cross-industry technology leaders and adapt these for our biopharmaceutical and healthcare 
industry clients. Some of these technologies supporting the industries we serve are changing rapidly and we must continue to adapt to 
these changes in a timely and effective manner at an acceptable cost. We also must continue to deliver data to our clients in forms that 
are easy to use while simultaneously providing clear answers to complex questions. There can be no guarantee that we will be able to 
develop, acquire or integrate new technologies, that these new technologies will meet our clients’ needs or achieve expected 
investment goals, or that we will be able to do so as quickly or cost-effectively as our competitors. Significant technological change 
could render certain of our services obsolete. Moreover, the introduction of new services embodying new technologies could render 
certain of our existing services obsolete. Our continued success will depend on our ability to adapt to changing technologies, manage 
and process ever-increasing amounts of data and information and improve the performance, features and reliability of our services in 
response to changing client and industry demands. We may experience difficulties that could delay or prevent the successful design, 
development, testing, introduction or marketing of our services. New services, or enhancements to existing services, may not 
adequately meet the requirements of current and prospective clients or achieve any degree of significant market acceptance. These 
types of failures could have a material adverse effect on our operating results and financial condition. 

Consolidation in the industries in which our clients operate may reduce the volume of services purchased by consolidated 

clients following an acquisition or merger, which could materially harm our operating results and financial condition. 

Mergers or consolidations among our clients have in the past and could in the future reduce the number of our clients and 

potential clients. When companies consolidate, overlapping services previously purchased separately are usually purchased only once 
by the combined entity, leading to loss of revenue. Other services that were previously purchased by one of the merged or 
consolidated entities may be deemed unnecessary or cancelled. If our clients merge with or are acquired by other entities that are not 
our clients, or that use fewer of our services, they may discontinue or reduce their use of our services. There can be no assurance as to 
the degree to which we may be able to address the revenue impact of such consolidation. Any of these developments could materially 
harm our operating results and financial condition. 

We may be adversely affected by client or therapeutic concentration. 

Although we did not have any client that represented 10% or more of our revenues in 2017, 2016 and 2015, we derive the 

majority of our revenues from a number of large clients. If any large client decreases or terminates its relationship with us, our 
business, results of operations or financial condition could be materially adversely affected.  

Additionally, conducting multiple clinical trials for different clients in a single therapeutic class involving drugs with the same 

or similar chemical action has in the past and may in the future adversely affect our business if some or all of the clinical trials are 
canceled because of new scientific information or regulatory judgments that affect the drugs as a class or if industry consolidation 
results in the rationalization of drug development pipelines. Similarly, marketing and selling drugs for different biopharmaceutical 
companies with similar chemical actions subjects us to risk if new scientific information or regulatory judgment prejudices the drugs 
as a class, which may lead to compelled or voluntary prescription limitations or withdrawal of some or all of such drugs from the 
market. 

23

Our business is subject to international economic, political and other risks that could negatively affect our results of 

operations and financial condition. 

We have significant operations in countries that may require complex arrangements to deliver services throughout the world 

for our clients. Additionally, we have established operations in locations remote from our most developed business centers. As a 
result, we are subject to heightened risks inherent in conducting business internationally, including the following: 

•

•

•

• 

• 

• 

• 

• 

•

•

required compliance with a variety of local laws and regulations which may be materially different than those to which 
we are subject in the United States or which may change unexpectedly; for example, conducting a single clinical trial 
across multiple countries is complex, and issues in one country, such as a failure to comply with local regulations or 
restrictions, may affect the progress of the clinical trial in the other countries, for example, by limiting the amount of 
data necessary for a clinical trial to proceed, resulting in delays or potential cancellation of contracts, which in turn 
may result in loss of revenue; 

the United States or foreign countries could enact legislation or impose regulations or other restrictions, including 
unfavorable labor regulations, tax policies or economic sanctions, which could have an adverse effect on our ability to 
conduct business in or expatriate profits from the countries in which we operate, including hiring, retaining and 
overseeing qualified management personnel for managing operations in multiple countries, differing employment 
practices and labor issues, and tax-related risks, including the imposition of taxes and the lack of beneficial treaties, 
that result in a higher effective tax rate for us; 

foreign countries are expanding or may expand their regulatory framework with respect to patient informed consent, 
protection and compensation in clinical trials, which could delay or inhibit our ability to conduct clinical trials in such 
jurisdictions; 

the regulatory or judicial authorities of foreign countries may not enforce legal rights and recognize business 
procedures in a manner in which we are accustomed or would reasonably expect; 

local, economic, political and social conditions, including potential hyperinflationary conditions, political instability, 
and potential nationalization, repatriation, expropriation, price controls or other restrictive government actions, 
including changes in political and economic conditions may lead to changes in the business environment in which we 
operate, as well as changes in foreign currency exchange rates; 

immigration laws are subject to legislative change and varying standards of application and enforcement due to 
political forces, economic conditions or other events (including proposals in the U.S. to change limitations on 
temporary and permanent workers), and local immigration laws may require us to meet certain other legal requirements 
as a condition to obtaining or maintaining entry visas, which may impact our ability to provide services to our clients; 

potential violations of local laws or anti-bribery laws, such as the United States Foreign Corrupt Practices Act 
(“FCPA”), and the UK Bribery Act, may cause difficulty in managing foreign operations, as well as significant 
consequences to us if those laws are violated; 

regulatory changes and economic conditions leading up to and following the UK’s likely exit from the EU (“Brexit”), 
including uncertainties as to its effect on trade laws, tariffs, instability and volatility in the global financial and 
currency markets, conflicting or redundant regulatory regimes in Europe, such as the European Medicines Agency 
(“EMA”) possible relocation from UK to a country within the European Union, and political stability; 

clients in foreign jurisdictions may have longer payment cycles, and it may be more difficult to collect receivables in 
foreign jurisdictions; and  

natural disasters, pandemics or international conflict, including terrorist acts, could interrupt our services, endanger our 
personnel or cause project delays or loss of clinical trial materials or results. 

These risks and uncertainties could negatively impact our ability to, among other things, perform large, global projects for our 

clients. Furthermore, our ability to deal with these issues could be affected by applicable United States laws and the need to protect 
our assets. Any such risks could have an adverse impact on our financial condition and results of operations. 

24

Exchange rate fluctuations may affect our results of operations and financial condition. 

Because a large portion of our revenues and expenses are denominated in currencies other than the United States dollar and our 

financial statements are reported in United States dollars, changes in foreign currency exchange rates could significantly affect our 
results of operations and financial condition. Exchange rate fluctuations between local currencies and the United States dollar create 
risk in several ways, including: 

• 

•

Foreign Currency Translation Risk. The revenue and expenses of our foreign operations are generally denominated in 
local currencies and translated into United States dollars for financial reporting purposes. Accordingly, exchange rate 
fluctuations will affect the translation of foreign results into United States dollars for purposes of reporting our 
consolidated results. 

Foreign Currency Transaction Risk. We are subject to foreign currency transaction risk for fluctuations in exchange 
rates during the period of time between the consummation and cash settlement of a transaction. We earn revenue from 
our service contracts over a period of several months and, in some cases, over several years. Accordingly, exchange 
rate fluctuations during this period may affect our profitability with respect to such contracts. 

We may limit these risks through exchange rate fluctuation provisions stated in our service contracts, or we may hedge our 

transaction risk with foreign currency exchange contracts or options. We have not, however, hedged all of our foreign currency 
transaction risk, and we may experience fluctuations in financial results from our operations outside the United States and foreign 
currency transaction risk associated with our service contracts. 

Due to the global nature of our business, we may be exposed to liabilities under anti-corruption laws, including the United 

States Foreign Corrupt Practices Act, the United Kingdom Bribery Act and various international anti-corruption laws, and any 
allegation or determination that we violated these laws could have a material adverse effect on our business. 

We are required to comply with the FCPA, the UK Bribery Act and other international anti-corruption laws, which prohibit 
companies from engaging in bribery including corruptly or improperly offering, promising, or providing money or anything else of 
value to non-United States officials and certain other recipients. In addition, the FCPA imposes certain books, records, and accounting 
control obligations on public companies and other issuers. We operate in parts of the world in which corruption can be common and 
compliance with anti-bribery laws may conflict with local customs and practices. Our global operations face the risk of unauthorized 
payments or offers being made by employees, consultants, sales agents, and other business partners outside of our control or without 
our authorization. It is our policy to implement safeguards to prohibit these practices by our employees and business partners with 
respect to our operations. However, irrespective of these safeguards, or as a result of monitoring compliance with such safeguards, it is 
possible that we or certain other parties may discover or receive information at some point that certain employees, consultants, sales 
agents, or other business partners may have engaged in corrupt conduct for which we might be held responsible. Violations of the 
FCPA, the UK Bribery Act or other international anti-corruption laws may result in restatements of, or irregularities in, our financial 
statements as well as severe criminal or civil sanctions, and we may be subject to other liabilities, which could negatively affect our 
business, operating results and financial condition. In some cases, companies that violate the FCPA may be debarred by the United 
States government and/or lose their United States export privileges. Changes in anti-corruption laws or enforcement priorities could 
also result in increased compliance requirements and related costs which could adversely affect our business, financial condition and 
results of operations. In addition, the United States or other governments may seek to hold us liable for successor liability FCPA 
violations or violations of other anti-corruption laws committed by companies in which we invest or that we acquired or will acquire. 

We face risks related to sales to government entities. 

We derive a portion of our revenue from sales to government entities in the United States. In general, our contracts with 

United States government entities are terminable at will by the government entity at any time. Government demand and payment for 
our services may be affected by public-sector budgetary cycles and funding authorizations, including government shutdowns. 
Government contracts are subject to oversight, including special rules on accounting, expenses, reviews and security. Failure to 
comply with these rules could result in civil and criminal penalties and sanctions, including termination of contracts, fines and 
suspensions, or debarment from future business with the United States government. As a result, failure to comply with these rules 
could have an adverse effect on our future business, reputation, operating results and financial condition. 

25

If we are unable to successfully develop and market new services or enter new markets, our growth, results of operations or 

financial condition could be adversely affected. 

A key element of our growth strategy is the successful development and marketing of new services or entering new markets 
that complement or expand our existing business. As we develop new services or enter new markets, including services targeted at 
participants in the broader healthcare industry, we may not have or adequately build the competencies necessary to perform such 
services satisfactorily, may not receive market acceptance for such services or may face increased competition. If we are unable to 
succeed in developing new services, entering new markets or attracting a client base for our new services or in new markets, we will 
be unable to implement this element of our growth strategy, and our future business, reputation, results of operations and financial 
condition could be adversely affected. 

Our Research & Development Solutions business could subject us to potential liability that may adversely affect our results 

of operations and financial condition. 

Our Research & Development Solutions business involves the testing of new drugs on patients in clinical trials and, if 

marketing approval is granted, the availability of these drugs to be prescribed to patients. Our involvement in the clinical trials and 
development process creates a risk of liability for personal injury to or death of patients, particularly those with life-threatening 
illnesses, resulting from adverse reactions to the drugs administered during testing or after product launch, respectively. For example, 
we have from time to time been sued and may be sued in the future by individuals alleging personal injury due to their participation in 
clinical trials and seeking damages from us under a variety of legal theories. Although we maintain the types and amounts of insurance 
we view as customary in the industries and countries in which we operate, if we are required to pay damages or incur defense costs in 
connection with any personal injury claim that is outside the scope of indemnification agreements we have with our clients, if any 
indemnification agreement is not performed in accordance with its terms or if our liability exceeds the amount of any applicable 
indemnification limits or available insurance coverage, our financial condition, results of operations and reputation could be materially 
and adversely affected. We maintain professional liability insurance, including liability for completed operations coverage. In the 
future, we may not be able to get adequate insurance for these types of risks at reasonable rates. 

We also contract with physicians to serve as investigators in conducting clinical trials. If the investigators commit errors or 

make omissions during a clinical trial that result in harm to clinical trial patients or after a clinical trial to a patient using the drug after 
it has received regulatory approval, claims for personal injury or liability damages may result. Additionally, if the investigators engage 
in fraudulent behavior, clinical trial data may be compromised, which may require us to repeat the clinical trial or subject us to 
liability. We do not believe we are legally responsible for the medical care rendered by such third-party investigators, and we would 
vigorously defend any claims brought against us. However, it is possible we could be found liable for claims with respect to the 
actions of third-party investigators, which may adversely affect our financial condition, results of operations and reputation. 

Some of our Research & Development Solutions services involve direct interaction with clinical trial subjects or volunteers 
and operation of Phase I clinical facilities, which could create potential liability that may adversely affect our results of operations 
and financial condition. 

We operate facilities where Phase I clinical trials are conducted, which ordinarily involve testing an investigational drug on a 

limited number of healthy individuals, typically 20 to 80 persons, to determine such drug’s basic safety. Failure to operate such a 
facility in accordance with applicable regulations could result in that facility being shut down, which could disrupt our operations. 
Additionally, we face risks associated with adverse events resulting from the administration of such drugs to healthy volunteers and 
the professional malpractice of medical care providers. Occasionally, physicians employed at our Phase I clinical facilities act as 
principal investigators in later-phase clinical trials at those same facilities. We also directly employ nurses and other trained 
employees who assist in implementing the testing involved in our clinical trials, such as drawing blood from healthy volunteers. Any 
professional malpractice or negligence by such investigators, nurses or other employees could potentially result in liability to us in the 
event of personal injury to or death of a healthy volunteer in clinical trials. This liability, particularly if it were to exceed the limits of 
any indemnification agreements and insurance coverage we may have, may adversely affect our financial condition, results of 
operations and reputation. 

26

Our Integrated Engagement Services business could result in liability to us if a drug causes harm to a patient. While we are 

generally indemnified and insured against such risks, we may still suffer financial losses. 

When we market drugs under contract for a biopharmaceutical company, we could suffer liability for harm allegedly caused by 

those drugs, either as a result of a lawsuit against the biopharmaceutical company to which we are joined, a lawsuit naming us or any 
of our subsidiaries or an action launched by a regulatory body. While we are generally indemnified by the biopharmaceutical company 
for the action of the drugs we market on its behalf, and we carry insurance to cover harm caused by our negligence in performing 
services, it is possible that we could nonetheless incur financial losses, regulatory penalties or both. In particular, any claim could 
result in potential liability for us if the claim is outside the scope of the indemnification agreement we have with the 
biopharmaceutical company, the biopharmaceutical company does not abide by the indemnification agreement as required or the 
liability exceeds the amount of any applicable indemnification limits or available insurance coverage. Such a finding could have an 
adverse impact on our financial condition, results of operations and reputation. Furthermore, negative publicity associated with harm 
caused by drugs we helped to market could have an adverse effect on our business and reputation. 

Our insurance may not cover all of our indemnification obligations and other liabilities associated with our operations. 

We maintain insurance designed to provide coverage for ordinary risks associated with our operations and our ordinary 

indemnification obligations. The coverage provided by such insurance may not be adequate for all claims we may make or may be 
contested by our insurance carriers. If our insurance is not adequate or available to pay liabilities associated with our operations, or if 
we are unable to purchase adequate insurance at reasonable rates in the future, our profitability may be adversely impacted. 

If we are unable to attract suitable investigators and patients for our clinical trials, our clinical development business might 

suffer. 

The timely recruitment of investigators and patients for clinical trials is essential to our Research & Development Solutions 
business. Investigators are typically located at hospitals, clinics or other sites and supervise the administration of the investigational 
drug to patients during the course of a clinical trial. Patients generally include people from the communities in which the clinical trials 
are conducted. Our clinical development business could be adversely affected if we are unable to attract suitable and willing 
investigators or patients for clinical trials on a consistent basis. For example, if we are unable to engage investigators to conduct 
clinical trials as planned or enroll sufficient patients in clinical trials, we might need to expend additional funds to obtain access to 
resources or else be compelled to delay or modify the clinical trial plans, which may result in additional costs to us. 

If we lose the services of key personnel or are unable to recruit additional qualified personnel, our business could be 

adversely affected. 

Our success substantially depends on the collective performance, contributions and expertise of our personnel including senior 

management and key personnel, qualified professional, scientific and technical operating staff and qualified sales representatives for 
our contract sales services. There is significant and increasing competition for qualified personnel, particularly those with higher 
educational degrees, such as a medical degree, a Ph.D. or an equivalent degree, or relevant experience in the industry and in the 
locations in which we operate. In addition, the departure of our key employees, or our inability to continue to identify, attract and 
retain qualified personnel or replace any departed personnel in a timely fashion, may impact our ability to grow our business and 
compete effectively in our industry and may negatively affect our ability to meet financial and operational goals. 

Disruptions in the credit and capital markets and unfavorable general economic conditions could negatively affect our 

business, results of operations and financial condition. 

Disruptions in the credit and capital markets could have negative effects on our business that may be difficult to predict or 

anticipate, including the ability of our clients, vendors, contractors and financing sources to meet their contractual obligations. 
Although we are unable to quantify the impact it has had on us, we are aware of a limited number of instances in our Research & 
Development Solutions business during the past several years where cancellations, changes in scope and failure to pay timely were 
attributable, at least in part, to difficulty in our clients’ ability to obtain financing. In the future such actions by our clients could, if 
they involve a significant amount of business with us, have a material adverse effect on our results of operations. 

27

Our effective income tax rate may fluctuate for a variety of reasons, including the Tax Cuts and Jobs Act enacted in 2017 

(the “Tax Act”), which may adversely affect our operations, earnings and earnings per share. 

Our effective income tax rate is influenced by our projected profitability in the various taxing jurisdictions in which we 
operate. Changes in a jurisdiction’s income tax rates and the distribution of our profits and losses among such jurisdictions may have a 
significant impact on our effective income tax rate, which in turn could have an adverse effect on our net income and earnings per 
share. Factors that may affect our effective income tax rate include, but are not limited to: 

•

•

• 

• 

•

• 

•

the requirement to exclude from our quarterly worldwide effective income tax calculations losses in jurisdictions where 
no income tax benefit can be recognized; 

actual and projected full year pre-tax income; 

changes in the valuation of deferred tax assets and liabilities; 

the repatriation of foreign earnings to the United States; 

changes in tax laws in various jurisdictions, including the Tax Act; 

audits by taxing authorities; and 

the establishment of valuation allowances against deferred income tax assets if we determined that it is more likely 
than not that future income tax benefits will not be realized.  

In addition, our effective income tax rate is influenced by U.S. tax law which has been substantially modified by the Tax 

Act.  The following provisions of the Tax Act could have an adverse effect on our tax rate if it is determined that the provisions are 
applicable to us:

•           Anti-base erosion and profit shifting; 

•           Global intangible low-taxed income; 

•           Deduction for net business interest limited to 30% of adjusted taxable income; and

•           Performance-based compensation and commissions now subject to $1 million limit. 

All of these items described above may cause fluctuations in our effective income tax rate through increased U.S. tax liability 

and/or the loss of tax attributes in any given year that could adversely affect our results of operations and impact our earnings and 
earnings per share. Additional information regarding our income taxes is presented in Note 18 to our audited consolidated financial 
statements included in this Annual Report on Form 10-K.

Changes in accounting standards issued by the Financial Accounting Standards Board (“FASB”), including ASC 606 

“Revenue from Contracts with Customers” (ASC 606), or other standard-setting bodies may adversely affect our financial 
statements.

We are required to prepare our financial statements in accordance with generally accepted accounting principles in the United 

States of America (“GAAP”), which is periodically revised and/or expanded. From time to time, we are required to adopt new or 
revised accounting standards issued by recognized authoritative bodies, including the FASB and the SEC. It is possible that future 
accounting standards we are required to adopt, such as amended guidance for leases, may require additional changes to the current 
accounting treatment that we apply to our financial statements and may require us to make significant changes to our reporting 
systems. Such changes could result in a material adverse impact on our business, results of operations and financial condition.

For example, effective January 1, 2018, we were required to adopt ASC 606. Under this new standard, the Company is 

required to recognize revenue for its clinical trial arrangements on a percentage of completion basis. This change in revenue 
recognition requires significant estimates of project costs that will need to be updated and adjusted on a regular basis. These updates 
and adjustments are likely to result in variability in our revenue recognition from period to period that may cause unexpected 
variability in our operating results. See Note 1 to our audited consolidated financial statements included elsewhere in this Annual 
Report on Form 10-K for details regarding ASC 606.

28

Our relationships with existing or potential clients who are in competition with each other may adversely impact the degree 

to which other clients or potential clients use our services, which may adversely affect our results of operations. 

The biopharmaceutical industry is highly competitive, with biopharmaceutical companies each seeking to persuade payers, 

providers and patients that their drug therapies are better and more cost-effective than competing therapies marketed or being 
developed by competing firms. In addition to the adverse competitive interests that biopharmaceutical companies have with each 
other, biopharmaceutical companies also have adverse interests with respect to drug selection and reimbursement with other 
participants in the healthcare industry, including payers and providers. Biopharmaceutical companies also compete to be first to 
market with new drug therapies. We regularly provide services to biopharmaceutical companies who compete with each other, and we 
sometimes provide services or funding to such clients regarding competing drugs in development. Our existing or future relationships 
with our biopharmaceutical clients may therefore deter other biopharmaceutical clients from using our services or may result in our 
clients seeking to place limits on our ability to serve other biopharmaceutical industry participants in connection with drug 
development activities. In addition, our further expansion into the broader healthcare market may adversely impact our relationships 
with biopharmaceutical clients, and such clients may elect not to use our services, reduce the scope of services that we provide to them 
or seek to place restrictions on our ability to serve clients in the broader healthcare market with interests that are adverse to theirs. A 
loss of clients or reductions in the level of revenues from a client could have a material adverse effect on our results of operations, 
business and prospects. 

If we are unable to successfully identify, acquire and integrate existing businesses, services and technologies, our business, 

results of operations and financial condition could be adversely impacted. 

We anticipate that a portion of our future growth may come from acquiring existing businesses, services or technologies. The 

success of any acquisition will depend upon, among other things, our ability to effectively integrate acquired personnel, operations, 
services and technologies into our business and to retain the key personnel and clients of our acquired businesses. In addition, we may 
be unable to identify suitable acquisition opportunities or obtain any necessary financing on commercially acceptable terms. We may 
also spend time and money investigating and negotiating with potential acquisition targets but not complete the transaction. Any 
future acquisition could involve other risks, including, among others, the assumption of additional liabilities and expenses, difficulties 
and expenses in connection with integrating the acquired companies and achieving the expected benefits, issuances of potentially 
dilutive securities or interest-bearing debt, loss of key employees of the acquired companies, transaction costs, diversion of 
management’s attention from other business concerns and, with respect to the acquisition of foreign companies, the inability to 
overcome differences in foreign business practices, language and customs. Our failure to identify potential acquisitions, complete 
targeted acquisitions and integrate completed acquisitions could have a material adverse effect on our business, financial condition and 
results of operations. 

Investments in our clients’ businesses or drugs and our related commercial rights strategies could have a negative impact 

on our financial performance. 

We may enter into arrangements with our clients or other drug companies in which we take on some of the risk of the potential 

success or failure of their businesses or drugs, including making strategic investments in our clients or other drug companies, 
providing financing to clients or other drug companies or acquiring an interest in the revenues from clients’ drugs or in entities 
developing a limited number of drugs. Our financial results would be adversely affected if these investments or the underlying drugs 
result in losses or do not achieve the level of success that we anticipate and/or our return or payment from the drug investment or 
financing is less than our direct and indirect costs with respect to these arrangements. 

 Our results of operations may be adversely affected if we fail to realize the full value of our goodwill and intangible assets. 

We assess the realizability of our indefinite-lived intangible assets and goodwill annually and conduct an interim evaluation 

whenever events or changes in circumstances, such as operating losses or a significant decline in earnings associated with the acquired 
business or asset, indicate that these assets may be impaired. For example, we recognized $40 million of impairment losses during the 
year ended December 31, 2017, for goodwill and intangible assets in Encore Health Resources LLC (“Encore”), which we sold in the 
third quarter of 2017. Our ability to realize the value of the goodwill and indefinite-lived intangible assets will depend on the future 
cash flows of the businesses we have acquired, which in turn depend in part on how well we have integrated these businesses into our 
own business. If we are not able to realize the value of the goodwill and indefinite-lived intangible assets, we may be required to incur 
material charges relating to the impairment of those assets. Such impairment charges could materially and adversely affect our 
operating results and financial condition. 

29

We face risks arising from the restructuring of our operations. 

From time to time, we have adopted restructuring plans to improve our operating efficiency through various means such as 

reduction of overcapacity, elimination of non-billable support roles or other realignment of resources. Restructuring presents 
significant potential risks of events occurring that could adversely affect us, including: 

• 

• 

• 

• 

• 

actual or perceived disruption of service or reduction in service standards to clients; 

the failure to preserve supplier relationships and distribution, sales and other important relationships and to resolve 
conflicts that may arise; 

loss of sales as we reduce or eliminate staffing on non-core services; 

diversion of management attention from ongoing business activities; and 

the failure to maintain employee morale and retain key employees. 

Further, any such restructuring would result in charges that, if material, could harm our results of operations and significantly 

reduce our cash position or increase debt. In addition, we may incur certain unforeseen costs once any restructuring activities are 
implemented. Further, if we determine to effect any restructuring, we can give no assurance that any projected cost reductions 
resulting from such restructuring activities will be achieved within the expected timeframe, or at all. 

Because of these and other factors, we cannot predict whether we will realize the purpose and anticipated benefits of these 

measures and, if we do not, our business and results of operations may be adversely affected. 

Additionally, there may be delays in implementing the restructuring activities or a failure to achieve the anticipated levels of 

cost savings and efficiency as a result of the restructuring activities, each of which could materially and adversely impact our business 
and results of operations. Further restructuring or reorganization activities may also be required in the future beyond what is currently 
planned, which could further enhance the risks associated with these activities. 

Risks Relating to Our Industry 

The biopharmaceutical services industry is highly competitive. 

The biopharmaceutical services industry is highly competitive. Our business often competes with other biopharmaceutical 

services companies, internal discovery departments, development departments, sales and marketing departments, information 
technology departments and other departments within our clients, some of which could be considered large biopharmaceutical services 
companies in their own right with greater resources than ours. We also compete with universities, teaching hospitals, governments 
agencies and others. If we do not compete successfully, our business will suffer. The industry is highly fragmented, with numerous 
smaller specialized companies and a handful of companies with global capabilities similar to certain of our own capabilities. Increased 
competition has led to price and other forms of competition, such as acceptance of less favorable contract terms, that could adversely 
affect our operating results. There are few barriers to entry for companies considering offering any one or more of the services we 
offer. Because of their size and focus, these companies might compete effectively against us, which could have a material adverse 
impact on our business. 

Our future growth and success will depend on our ability to successfully compete with other companies that provide similar 

services in the same markets, some of which may have financial, marketing, technical and other advantages. We also expect that 
competition will continue to increase as a result of consolidation among these various companies. Large technology companies with 
substantial resources, technical expertise and greater brand power could also decide to enter or further expand in the markets where 
our business operates and compete with us. If one or more of our competitors or potential competitors were to merge or partner with 
another of our competitors, or if a new entrant emerged with substantial resources, the change in the competitive landscape could 
adversely affect our ability to compete effectively. We compete on the basis of various factors, including breadth and depth of 
services, reputation, reliability, quality, innovation, security, price and industry expertise and experience. In addition, our ability to 
compete successfully may be impacted by the growing availability of health information from social media, government health 
information systems and other free or low-cost sources. Consolidation or integration of wholesalers, retail pharmacies, health 
networks, payers or other healthcare stakeholders may lead any of them to provide information services directly to clients or indirectly 
through a designated service provider, resulting in increased competition from firms that may have lower costs to market (e.g., no data 
supply costs). Any of the above may result in lower demand for our services, which could result in a material adverse impact on our 
operating results and financial condition. 

30

Outsourcing trends in the biopharmaceutical industry and changes in aggregate spending and research and development 

budgets could adversely affect our operating results and growth rate. 

Economic factors and industry trends that affect biopharmaceutical companies affect our Research & Development Solutions 

business. Biopharmaceutical companies continue to seek long-term strategic collaborations with global contract research organizations 
with favorable pricing terms. Competition for these collaborations is intense and we may decide to forego an opportunity or we may 
not be selected, in which case a competitor may enter into the collaboration and our business with the client, if any, may be limited. In 
addition, if the biopharmaceutical industry reduces its Research & Development Solutions activities or reduces its outsourcing of 
clinical trials and sales and marketing projects or such outsourcing fails to grow at projected rates, our operations and financial 
condition could be materially and adversely affected. We may also be negatively impacted by consolidation and other factors in the 
biopharmaceutical industry, which may slow decision making by our clients or result in the delay or cancellation of clinical trials. Our 
commercial services may be affected by reductions in new drug launches and increases in the number of drugs losing patent 
protection. All of these events could adversely affect our business, results of operations or financial condition. 

Our business may be materially and adversely impacted by factors affecting the biopharmaceutical and healthcare 

industries. 

The vast majority of our revenue is generated from sales to the biopharmaceutical and healthcare industries. The clients we 
serve in these industries are commonly subject to financial pressures, including, but not limited to, increased costs, reduced demand 
for their products, reductions in pricing and reimbursement for products and services, formulary approval and placement, government 
approval to market their products and limits on the manner by which they market their products, loss of patent exclusivity (whether 
due to patent expiration or as a result of a successful legal challenge) and the proliferation of or changes to regulations applicable to 
these industries. To the extent our clients face such pressures, or they change how they utilize our offerings, the demand for our 
services, or the prices our clients are willing to pay for those services, may decline. Any such decline could have a material adverse 
effect on our business, operating results and financial condition. 

We may be affected by healthcare reform and potential additional reforms. 

The United States Congress continues to consider healthcare reform legislation and impose health industry cost containment 
measures, which may significantly impact the biopharmaceutical industry. In addition, numerous government bodies are considering 
or have adopted various healthcare reforms and may undertake, or are in the process of undertaking, efforts to control growing 
healthcare costs through legislation, regulation and voluntary agreements with medical care providers and biopharmaceutical 
companies. We are uncertain as to the effects of these recent reforms on our business and are unable to predict what legislative 
proposals, if any, will be adopted in the future. If regulatory cost containment efforts limit the profitability of new drugs, our clients 
may reduce their research and development spending or promotional, marketing and sales expenditures, which could reduce the 
business they outsource to us. Similarly, if regulatory requirements are relaxed or simplified drug approval procedures are adopted, the 
demand for our services could decrease. 

Foreign and domestic government bodies may also adopt healthcare legislation or regulations that are more burdensome than 
existing regulations. For example, product safety concerns and recommendations by the Drug Safety Oversight Board could change 
the regulatory environment for drug products, and new or heightened regulatory and licensing requirements may increase our expenses 
or limit or delay our ability to offer some of our services. Additionally, new or heightened regulatory requirements may have a 
negative impact on the ability of our clients to conduct industry-sponsored clinical trials, which could reduce the need for our services. 

Actions by government regulators or clients to limit a prescription’s scope or withdraw an approved drug from the market 

could adversely affect our business and result in a loss of revenues. 

Government regulators have the authority, after approving a drug, to regulate or limit its scope of prescription or withdraw it 

from the market completely based on safety concerns. Similarly, clients may act to voluntarily limit the scope of prescription of drugs 
or withdraw them from the market. In the past, we have provided services with respect to drugs that have been limited and/or 
withdrawn. If we are providing services to clients for drugs that are limited or withdrawn, we may be required to narrow the scope of 
or terminate our services with respect to such drugs, which would prevent earning the full amount of revenues anticipated under the 
related service contracts with negative impacts to our financial results. 

31

If we do not keep pace with rapid technological changes, our services may become less competitive or obsolete. 

The biopharmaceutical industry is subject to rapid technological changes. Our current competitors or other businesses might 

develop technologies or services that are more effective or commercially attractive than, or render obsolete, our current or future 
technologies and services. If our competitors introduce superior technologies or services and if we cannot make enhancements to 
remain competitive, our competitive position would be harmed. If we are unable to compete successfully, we may lose clients or be 
unable to attract new clients, which could lead to a decrease in our revenue and financial condition. 

Laws restricting biopharmaceutical sales and marketing practices may adversely impact demand for our services. 

There have been a significant number of laws, legislative initiatives and regulatory actions over the years that seek to limit 

biopharmaceutical sales and marketing practices. For example, three states in 2006 and 2007 passed laws restricting the use of 
prescriber identifiable information for the purpose of promoting branded prescription medicines. Although these laws were 
subsequently declared to be unconstitutional based on a decision of the U.S. Supreme Court in Sorrell v. IMS Health in 2011, we are 
unable to predict whether, and in what form, other initiatives may be introduced or actions taken at the state or Federal levels to limit 
biopharmaceutical sales and marketing practices. In addition, while we will continue to seek to adapt our services to comply with the 
requirements of these laws (to the extent applicable to our services), if enacted, there can be no assurance that our efforts to adapt our 
offerings will be successful and provide the same financial contribution to us. There can also be no assurance that future legislative 
initiatives will not adversely affect our ability to develop or market current or future offerings, or that any future laws will not 
diminish the demand for our services, all of which could, over time, result in a material adverse impact on our operating results and 
financial condition. 

Our Research & Development Solutions clients face intense competition from lower cost generic products, which may 

lower the amount that they spend on our services. 

Our Research & Development Solutions clients face increasing competition from lower cost generic products, which in turn 

may affect their ability to pursue research and development activities with us. In the United States, EU and Japan, political pressure to 
reduce spending on prescription drugs has led to legislation and other measures which encourages the use of generic products. In 
addition, proposals emerge from time to time in the United States and other countries for legislation to further encourage the early and 
rapid approval of generic drugs. Loss of patent protection for a product typically is followed promptly by generic substitutes, reducing 
our clients’ sales of that product and their overall profitability. Availability of generic substitutes for our clients’ drugs may adversely 
affect their results of operations and cash flow, which in turn may mean that they would not have surplus capital to invest in research 
and development and drug commercialization, including in our services. If competition from generic products impacts our clients’ 
finances such that they decide to curtail our services, our revenues may decline and this could have a material adverse effect on our 
business. 

32

Risks Relating to Our Indebtedness 

Restrictions imposed in the Senior Secured Credit Facilities and other outstanding indebtedness, including the indentures 

governing IQVIA Holdings Inc. outstanding notes, may limit our ability to operate our business and to finance our future 
operations or capital needs or to engage in other business activities. 

The terms of the Senior Secured Credit Facilities restrict IQVIA and its restricted subsidiaries from engaging in specified types 

of transactions. These covenants restrict the ability of IQVIA and its restricted subsidiaries, among other things, to: 

•

•

• 

•

• 

•

• 

• 

• 

•

 •

• 

incur liens; 

make investments and loans; 

incur indebtedness or guarantees; 

issue preferred stock of a restricted subsidiary; 

issue disqualified equity; 

engage in mergers, acquisitions and asset sales; 

declare dividends, make payments or redeem or repurchase equity interests; 

alter the business IQVIA and its restricted subsidiaries conduct; 

make restricted payments; 

enter into agreements limiting restricted subsidiary distributions; 

prepay, redeem or purchase certain indebtedness; and 

engage in certain transactions with affiliates. 

In addition, the revolving credit facility and the new term loans under our senior secured credit facility require IQVIA to 

comply with a quarterly maximum senior secured net leverage ratio test and minimum interest coverage ratio test. IQVIA’s ability to 
comply with these financial covenants can be affected by events beyond our control, and IQVIA may not be able to satisfy them. 
Additionally, the restrictions contained in the indentures governing the outstanding notes could also limit our ability to plan for or 
react to market conditions, meet capital needs or make acquisitions or otherwise restrict our activities or business plans. 

A breach of any of these covenants could result in a default under the Senior Secured Credit Facilities or the indentures 
governing the outstanding notes, which could trigger acceleration of our indebtedness and may result in the acceleration of or default 
under any other debt to which a cross-acceleration or cross-default provision applies, which could have a material adverse effect on 
our business, operations and financial results. In the event of any default under the Senior Secured Credit Facilities, the applicable 
lenders could elect to terminate borrowing commitments and declare all borrowings and loans outstanding, together with accrued and 
unpaid interest and any fees and other obligations, to be due and payable. In addition, or in the alternative, the applicable lenders could 
exercise their rights under the security documents entered into in connection with the Senior Secured Credit Facilities. IQVIA and the 
other subsidiary guarantors have pledged substantially all of their tangible and intangible assets (subject to customary exceptions) as 
collateral under the Senior Secured Credit Facilities, including the stock and the assets of certain of our current and future wholly 
owned United States subsidiaries and a portion of the stock of certain of our non-United States subsidiaries. 

If we were unable to repay or otherwise refinance these borrowings and loans when due, the applicable lenders could proceed 
against the collateral granted to them to secure that indebtedness, which could force us into bankruptcy or liquidation. In the event the 
applicable lenders accelerate the repayment of our borrowings, we and our subsidiaries may not have sufficient assets to repay that 
indebtedness. Any acceleration of amounts due under the credit agreement governing the Senior Secured Credit Facilities or the 
exercise by the applicable lenders of their rights under the security documents would likely have a material adverse effect on us. 

33

Despite our level of indebtedness, we are able to incur more debt and undertake additional obligations. Incurring such debt 

or undertaking such additional obligations could further exacerbate the risks to our financial condition. 

Although our credit agreement, which governs the senior credit facilities of our wholly owned subsidiary through which we 

conduct our operations, IQVIA Inc. (“OpCo”), contains restrictions on the incurrence of additional indebtedness, these restrictions are 
subject to a number of qualifications and exceptions and the indebtedness incurred in compliance with these restrictions could 
increase. In addition, the receivables financing agreement for our special purpose subsidiary, IQVIA Funding, LLC (“IQVIA 
Funding”) limits borrowing based on the amount of receivables purchased by IQVIA Funding from certain of our other subsidiaries, 
but when supported by the value of such purchased receivables, the debt under our receivables financing facility can increase. 

While the credit agreement also contains restrictions on our and our restricted subsidiaries’ ability to make loans and 
investments, these restrictions are subject to a number of qualifications and exceptions, and the investments incurred in compliance 
with these restrictions could be substantial.  

Restrictive covenants in our other indebtedness may limit our flexibility in our current and future operations, particularly 

our ability to respond to changes in our business or to pursue our business strategies. 

The terms contained in certain of our indebtedness, including credit facilities and any future indebtedness of ours, may include 

a number of restrictive covenants that impose significant operating and financial restrictions, including restrictions on our and our 
restricted subsidiaries’ ability to take actions that we believe may be in our interest. These agreements, among other things, limit our 
ability to: 

• 

•

• 

•

• 

•

• 

•

• 

•

• 

•

incur additional debt; 

provide guarantees in respect of obligations of other persons; 

issue redeemable stock and preferred stock; 

pay dividends or distributions or redeem or repurchase capital stock; 

prepay, redeem or repurchase debt; 

make loans, investments and capital expenditures; 

enter into transactions with affiliates; 

create or incur liens; 

make distributions from our subsidiaries; 

sell assets and capital stock of our subsidiaries; 

make acquisitions; and 

consolidate or merge with or into, or sell substantially all of our assets to, another person. 

A breach of the covenants or restrictions under the agreements governing our other indebtedness could result in a default under 

the applicable indebtedness. Such default may allow the creditors to accelerate the related debt and may result in the acceleration of 
any other debt to which a cross-acceleration or cross-default provision applies. In the event our lenders and noteholders accelerate the 
repayment of our borrowings, we cannot assure that we and our subsidiaries would have sufficient assets to repay such indebtedness. 

Our financial results, our substantial indebtedness and our credit ratings could adversely affect the availability and terms of 

future financing. 

34

Interest rate fluctuations and our ability to deduct interest expense may affect our results of operations and financial 

condition. 

Because we have variable rate debt, fluctuations in interest rates affect our business. We attempt to minimize interest rate risk 

and lower our overall borrowing costs through the utilization of derivative financial instruments, primarily interest rate caps and 
swaps. We have entered into interest rate caps and swaps with financial institutions that have reset dates and critical terms that match 
those of our senior secured term loan credit facility. Accordingly, any change in market value associated with the interest rate caps and 
swaps is offset by the opposite market impact on the related debt. Because we do not attempt to hedge all of our variable rate debt, we 
may incur higher interest costs for the portion of our variable rate debt which is not hedged.    

In addition, the deduction for our interest expense may be limited, which could have an adverse impact on our taxes and net 

income.  

Risks Relating to Ownership of Our Common Stock 

The parties to the Shareholders Agreement continue to have significant influence over us, including control over decisions 

that require the approval of stockholders, which could limit the ability of other stockholders to influence the outcome of matters 
submitted to stockholders for a vote. 

As of February 12, 2018, certain parties to a Shareholders Agreement dated May 3, 2016 (the “Shareholders Agreement”) own 

approximately 24.9% of the outstanding shares of our common stock.

The parties to the Shareholders Agreement, other than Dr. Dennis Gillings and certain of his affiliates (the “DG Shareholders”) 

(who have agreed separately to vote in favor of the merger and the transactions contemplated thereby), have agreed to vote for 
individuals designated to the Company’s board of directors as follows: 

• 

•

• 

•

•

• 

Ari Bousbib (as our Chief Executive Officer); 

one individual designated by the TPG Shareholders (as defined in the Shareholders Agreement) (until the time at which 
the TPG Shareholders beneficially own, as a group, less than 5% of our outstanding common stock); 

another individual designated by the TPG Shareholders (until the earlier of (i) the seven year anniversary of 
completion of the Merger and (ii) time at which the TPG Shareholders beneficially own, as a group, 5% or more but 
less than 12% of our outstanding common stock); 

one individual designated by each of Bain Capital Investors, LLC (“Bain Capital”), the LGP Shareholders and the CPP 
Shareholder (each until the earlier of (i) the day after our 2018 annual meeting of stockholders or (ii) the time at which 
such stockholder group beneficially owns less than 2.5% of our outstanding common stock); 

four individuals who are non-stockholder, independent directors; and 

until the Company’s 2018 annual meeting of stockholders, one individual designated by remaining Quintiles Nominees 
(as defined in the Shareholders Agreement). 

The Shareholders Agreement provides that we will use our best efforts to cause Dr. Gillings to be elected as the Lead Director 

through our 2018 annual meeting of stockholders and to be elected as a director so that he may serve as a director until the day after 
our 2021 annual meeting of stockholders (provided that the DG Shareholders, as a group, continue to beneficially own at least 2.5% of 
our outstanding common stock), including using its best efforts to support his nomination for the slate of director nominees for a three-
year term at our 2020 annual meetings of stockholders. 

In 2017, the LGP Shareholders and the TPG Shareholders each ceased having the right to appoint one director to the Board. 

Following the secondary offering that closed on September 19, 2017, the LGP Shareholders holdings of our outstanding common 
stock fell below 2.5%. Following the secondary offering that closed on November 30, 2017, the TPG Shareholders holdings of our 
outstanding common stock fell below 12%. As a result, pursuant to the Shareholders Agreement, Mr. Danhakl offered to tender his 
resignation and the TPG Shareholders offered to tender the resignation of one of its two representatives on the Board. The TPG 
Shareholders continue to have the right to appoint one remaining director to the Board. After review, the Nominating and Governance 
Committee of the Board declined the offers made by Mr. Danhakl and the TPG Shareholders.

35

Even though the LGP Shareholders and the TPG Shareholders each lost the right to appoint one director to the Board, the 

parties to the Shareholders Agreement potentially still have the ability to influence decisions of our company to enter into any 
corporate transaction (and the terms thereof), any change in the composition of our board of directors and any transaction that requires 
stockholder approval regardless of whether others believe that such change or transaction is in the best interests of our company. 
Additionally, the parties to the Shareholders Agreement are in the business of making investments in companies and may from time to 
time acquire and hold interests in businesses that compete directly or indirectly with us. One or more of the parties to the Shareholders 
Agreement may also pursue acquisition opportunities that may be complementary to our businesses and, as a result, those acquisition 
opportunities may not be available to us. So long as the parties to the Shareholders Agreement continue to own a significant amount of 
our equity, if they exercise their stockholder rights collectively, they will be able to significantly influence our decisions.  

Provisions of the corporate governance documents of IQVIA could make an acquisition of IQVIA difficult and may 

prevent attempts by its stockholders to replace or remove its management, even if beneficial to its stockholders. 

In addition to the beneficial ownership of a large percentage of IQVIA common stock by the parties to the Shareholders 

Agreement, our certificate of incorporation and Delaware bylaws and the General Corporation Law of Delaware (“DGCL”) contain 
provisions that could make it difficult for a third party to acquire IQVIA even if doing so might be beneficial to its stockholders, 
including: 

• 

• 

• 

• 

• 

•

• 

the division of the board of directors into three classes and the election of each class for three-year terms; 

subject to the Shareholders Agreement, the sole ability of the board of directors to fill a vacancy created by the death or 
resignation of a director or the expansion of the board of directors; 

advance notice requirements for stockholder proposals and director nominations; 

limitations on the ability of stockholders to call special meetings and to take action by written consent; 

the approval of holders of at least seventy-five percent (75%) of the outstanding shares of IQVIA entitled to vote on 
any amendment, alteration, change, addition or repeal of the Delaware bylaws is required to amend, alter, change, add 
to or repeal the Delaware bylaws; 

the required approval of holders of at least seventy-five percent (75%) of the outstanding shares of IQVIA to remove 
directors, which removal may only be for cause, subject to different requirements in the case of directors elected by a 
voting group of stockholders and the terms of the Shareholders Agreement; and 

the ability of the board of directors to issue new series of, and designate the terms of, preferred stock, without 
stockholder approval, which could be used to, among other things, institute a rights plan that would have the effect of 
significantly diluting the stock ownership of a potential hostile acquirer, likely preventing acquisitions that have not 
been approved by the board of directors. 

In addition, IQVIA is subject to Section 203 of the DGCL regulating corporate takeovers, although our board of directors 
adopted a resolution approving the Merger pursuant to which shares of common stock were acquired, by among others, the TPG 
Shareholders. Section 203, subject to certain exceptions, prohibits a Delaware corporation from engaging in any “business 
combination” with any “interested stockholder” for a period of three years following the date that such stockholder became an 
interested stockholder unless: 

•

•

• 

prior to such date, the board of directors of the corporation approved either the business combination or the transaction 
that resulted in the stockholder becoming an interested stockholder; 

upon consummation of the transaction that resulted in the stockholder becoming an interested stockholder, the 
interested stockholder owned at least 85% of the voting stock of the corporation outstanding at the time the transaction 
commenced, excluding those shares owned by persons who are directors and also officers, and employee stock plans in 
which employee participants do not have the right to determine confidentially whether shares held subject to the plan 
will be tendered in a tender or exchange offer; or 

on or subsequent to such date, the business combination is approved by the board of directors and authorized at an 
annual or special meeting of stockholders, and not by written consent, by the affirmative vote of at least two-thirds of 
the outstanding voting stock that is not owned by the interested stockholder. 

36

In general, Section 203 defines “business combination” to include mergers or consolidations between a Delaware corporation 

and an interested stockholder, transactions with an interested stockholder involving the assets or stock of the corporation or its 
majority-owned subsidiaries and transactions which increase an interested stockholder’s percentage ownership of stock. In general, 
Section 203 defines an “interested stockholder” as any entity or person beneficially owning 15% or more of the outstanding voting 
stock of the corporation and any entity or person affiliated with or controlling or controlled by such entity or person. These provisions 
may frustrate or prevent any attempts by stockholders to replace members of the board of directors. Because IQVIA’s board is 
responsible for appointing the members of management, these provisions could in turn affect any attempt to replace current members 
of management. As a result, stockholders of IQVIA may lose their ability to sell their stock for a price in excess of the prevailing 
market price due to these protective measures, and efforts by stockholders to change the direction or management of IQVIA may be 
unsuccessful. 

Our operating results and share price may be volatile, which could cause the value of our stockholders’ investments to 

decline. 

Our quarterly and annual operating results may fluctuate in the future, and such fluctuations may be significant. In addition, 
securities markets worldwide have experienced, and are likely to continue to experience, significant price and volume fluctuations. 
This market volatility, as well as general economic, market or political conditions, could subject the market price of our shares to wide 
price fluctuations regardless of our operating performance. Our operating results and the trading price of our shares may fluctuate in 
response to various factors, including: 

•

• 

• 

•

• 

•

• 

•

• 

•

market conditions in the broader stock market; 

actual or anticipated fluctuations in our quarterly and annual financial and operating results; 

introduction of new services by us or our competitors; 

issuance of new or changed securities analysts’ reports or recommendations; 

sales, or anticipated sales, of large blocks of our stock; 

additions or departures of key personnel; 

regulatory or political developments; 

litigation and governmental investigations; 

changing economic conditions; and 

exchange rate fluctuations. 

These and other factors, many of which are beyond our control, may cause our operating results and the market price for our 

shares to fluctuate substantially. While we believe that operating results for any particular quarter are not necessarily a meaningful 
indication of future results, fluctuations in our quarterly operating results could limit or prevent investors from readily selling their 
shares and may otherwise negatively affect the market price and liquidity of our shares. In addition, in the past, when the market price 
of a stock has been volatile, holders of that stock have sometimes instituted securities class action litigation against the company that 
issued the stock. If any of our stockholders brought a lawsuit against us, we could incur substantial costs defending the lawsuit. Such a 
lawsuit could also divert the time and attention of our management from our business, which could significantly harm our profitability 
and reputation. 

There may be sales of a substantial amount of our common stock by our current stockholders, and these sales could cause 

the price of our common stock to fall. 

As of February 12, 2018, there were 208,251,468 shares of common stock outstanding. Approximately 24.9% of the 

outstanding shares of our common stock is held by parties to the Shareholders Agreement.  

Sales of substantial amounts of our common stock in the public market, or the perception that such sales will occur, could 
adversely affect the market price of our common stock and make it difficult for us to raise funds through securities offerings in the 
future. For example, as restrictions on resale end, the market price of our common stock could decline if the holders of currently 
restricted shares sell them or are perceived by the market as intending to sell them. 

37

Stockholders that are a party to the Shareholders Agreement may require us to register their shares for resale under the federal 

securities laws, subject to certain requirements. Under the Shareholders Agreement, we are required to pay the registration expenses 
associated with the registration of such shares, not including the underwriting discounts, commissions and transfer taxes. Registration 
of those shares would allow those stockholders to immediately resell their shares in the public market. Any such sales or the 
anticipation of such sales may cause the market price of our common stock to decline. In 2017, the parties to the Shareholders 
Agreement sold approximately 47.2 million shares of our common stock, of which we repurchased approximately 19.7 million shares.  

In addition, we may use our cash, cash generated from operations or dispositions of assets or businesses and/or proceeds from 
any new financing arrangements or issuances of debt or equity securities to repurchase shares, including the repurchase of shares from 
our stockholders that are a party to the Shareholders Agreement. 

Since we have no current plans to pay regular cash dividends on our common stock, stockholders may not receive any 

return on investment unless they sell their common stock for a price greater than that which they paid for it. 

Although we have previously declared dividends to our stockholders prior to our initial public offering in May 2013, we do 
not currently anticipate paying any regular cash dividends on our common stock. Any decision to declare and pay dividends in the 
future will be made at the discretion of our Board and will depend on, among other things, our results of operations, financial 
condition, cash requirements, contractual restrictions and other factors that our Board may deem relevant. In addition, our ability to 
pay dividends is, and may be, limited by covenants of existing and any future outstanding indebtedness we or our subsidiaries incur, 
including under our existing credit facilities. Therefore, any return on investment in our common stock is solely dependent upon the 
appreciation of the price of our common stock on the open market, which may not occur. 

Our certificate of incorporation contains a provision renouncing any interest and expectancy in certain corporate 

opportunities identified by certain of our affiliates, even if such corporate opportunities are ones that we might reasonably be 
deemed to have pursued or had the ability or desire to pursue. 

Our certificate of incorporation provides that our company renounces any interest or expectancy in the business opportunities 
of the TPG Shareholders, the Bain Capital, CPP Investment Board Private Holdings Inc. (“CPP Shareholder”), and Leonard Green & 
Partners, L.P. (“LGP Shareholders”), and their affiliates (other than our company and our subsidiaries) and all of their respective 
partners, principals, directors, officers, members, managers, managing directors and/or employees, and each such person will have no 
obligation to offer us such opportunities. This provision applies to these stockholders (and associated parties) only for so long as a 
nominee designated by the stockholder under the Shareholders Agreement continues to serve on the board. Stockholders are deemed 
to have notice of and have consented to this provision of our certificate of incorporation. 

Therefore, a director or officer of our company who also serves as a director, officer, member, manager, or employee of such 

stockholders may pursue certain business opportunities, including acquisitions, that may be complementary to its business and, as a 
result, such opportunities may not be available to us. These potential conflicts of interest could have a material adverse effect on the 
business, financial condition, results of operations, or prospects of our company if attractive corporate opportunities are allocated by 
such stockholders to themselves or their other affiliates instead of to us.  

Item 1B. Unresolved Staff Comments 

None. 

Item 2. Properties 

As of December 31, 2017, we had approximately 282 offices located in approximately 83 countries. Our executive 
headquarters are located adjacent to Research Triangle Park, North Carolina, and in Danbury, Connecticut. We own facilities in 
Barcelona, Spain; Buenos Aires, Argentina; Caracas, Venezuela; Los Ruices, Venezuela; Lisbon, Portugal and Bangalore, India. All 
of our other offices are leased. Our properties are geographically distributed to meet our worldwide operating requirements, and none 
of our properties are individually material to our business operations. Many of our leases have an option to renew, and we believe that 
we will be able to successfully renew expiring leases on terms satisfactory to us. We believe that our facilities are adequate for our 
operations and that suitable additional space will be available if needed. 

38

Item 3. Legal Proceedings

We are involved in a variety of legal and tax proceedings, claims and litigation that arise from time to time in the ordinary 

course of business. These actions may be commenced by various parties, including competitors, clients, current or former employees, 
government agencies or others. We record a provision with respect to a proceeding, claim or litigation when it is probable that a 
liability has been incurred and the amount of the loss can be reasonably estimated. However, even in instances where we have 
recorded an estimated liability, we are unable to predict with certainty the final outcome of the matter or whether resolution of the 
matter will materially affect our operating results, financial position or cash flows. As additional information becomes available, we 
adjust our assessment and estimates of such liabilities accordingly. 

Further, we routinely enter into agreements with our suppliers to acquire data and with our clients to sell data, all in the normal 

course of business. In these agreements, we sometimes agree to indemnify and hold harmless the other party for any damages such 
other party may suffer as a result of potential intellectual property infringement and other claims related to the use of the data. We 
have not accrued liability with respect to these matters, as the exposure is considered remote. 

Based on our review of the latest information available, management does not expect the impact of pending legal and tax 

proceedings, claims and litigation, either individually or in the aggregate, to have a material adverse effect on our operating results, 
financial position or cash flows. However, one or more unfavorable outcomes in any claim or litigation against us could have a 
material adverse effect for the period in which it is resolved. The following is a summary of the more significant legal matters 
involving the company. 

Our wholly-owned subsidiary, IMS Government Solutions Inc., is primarily engaged in providing services under contracts 

with the United States government. United States government contracts are subject to extensive legal and regulatory requirements and, 
from time to time, agencies of the United States government have the ability to investigate whether contractors’ operations are being 
conducted in accordance with such requirements. IMS Government Solutions discovered potential noncompliance with various 
contract clauses and requirements under its General Services Administration Contract (the “GSA Contract”) which was awarded in 
2002 to its predecessor company, Synchronous Knowledge Inc. (Synchronous Knowledge Inc. was acquired by IMS Health in May 
2005). The potential noncompliance arose from two primary areas: first, at the direction of the government, work performed under one 
task order was invoiced under another task order without the appropriate modifications to the orders being made; and second, 
personnel who did not meet strict compliance with the labor categories component of the qualification requirements of the GSA 
Contract were assigned to contracts. Upon discovery of the potential noncompliance, we began remediation efforts, promptly 
disclosed the potential noncompliance to the United States government, and were accepted into the Department of Defense Voluntary 
Disclosure Program. We filed a Voluntary Disclosure Program Report on August 29, 2008. We are currently unable to determine the 
outcome of all of these matters pending the resolution of the Voluntary Disclosure Program process and the ultimate liability arising 
from these matters could exceed our current reserves. 

On February 13, 2014, a group of approximately 1,200 medical doctors and 900 private individuals filed a civil lawsuit with 

the Seoul Central District Court against IMS Korea and two other defendants, KPA and the Korean Pharmaceutical Information 
Center (“KPIC”). The civil lawsuit alleges KPA and KPIC collected their personal information in violation of applicable privacy laws 
without the necessary consent through a software system installed on pharmacy computer systems in Korea, and that personal 
information was transferred to IMS Korea and sold to pharmaceutical companies. On September 11, 2017, the District Court issued a 
final decision that the encryption in use by the defendants since June 2014 was adequate to meet the requirements of the Korean 
Personal Information Privacy Act (“PIPA”) and the sharing of non-identified information for market research purposes was allowed 
under PIPA. The District Court also found an earlier version of encryption was insufficient to meet PIPA requirements, but no 
personal data had been leaked or re-identified. The District Court did not award any damages to plaintiffs. Approximately 280 medical 
doctors and 200 private individuals appealed the District Court decision. The Company believes the appeal is without merit and 
intends to vigorously defend its position.    

 On July 23, 2015, indictments were issued by the Seoul Central District Prosecutors’ Office in South Korea against 24 

individuals and companies alleging improper handling of sensitive health information in violation of, among others, South Korea’s 
Personal Information Protection Act. IMS Korea and two of its employees were among the individuals and organizations indicted. 
Although there is no assertion that IMS Korea used patient identified health information in any of its offerings, prosecutors allege that 
certain of IMS Korea’s data suppliers should have obtained patient consent when they converted sensitive patient information into 
non-identified data and that IMS Korea had not taken adequate precautions to reduce the risk of re-identification. We believe the 
indictment is without merit that we acted in compliance with all applicable laws at all times and intend to vigorously defend our 
position.

39

On January 10, 2017, IQVIA Inc., IMS Health Incorporated and IMS Software Services, Inc. (collectively “IQVIA Parties”) 

filed a lawsuit in the U.S. District Court for the District of New Jersey against Veeva Systems, Inc. (“Veeva”) alleging Veeva 
unlawfully used IQVIA Parties intellectual property to improve Veeva data offerings, to promote and market Veeva data offerings and 
to improve Veeva technology offerings. IQVIA Parties seek injunctive relief, appointment of a monitor, the award of compensatory 
and punitive damages and reimbursement of all litigation expenses, including reasonable attorneys’ fees and costs. On March 13, 
2017, Veeva filed counterclaims alleging anticompetitive business practices in violation of the Sherman Act and state laws. Veeva 
claims damages in excess of $200 million, and is seeking punitive damages and litigation costs, including attorneys’ fees. We believe 
the counterclaims are without merit, reject all counterclaims raised by Veeva and intend to vigorously defend IQVIA Parties’ position 
and pursue our claims against Veeva.

For additional information, see Note 13 to our audited consolidated financial statements included elsewhere in this Annual 

Report on Form 10-K.

Item 4. Mine Safety Disclosures 

Not applicable. 

40

PART II

Item 5. Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities 

Market Information for Common Stock 

Our common stock trades on the NYSE under the symbol “IQV.” The following table sets forth the high and low sales prices 

per share of our common stock as reported by the NYSE for the periods indicated. 

Fiscal Year 2016
First Quarter
Second Quarter
Third Quarter
Fourth Quarter

Fiscal Year 2017
First Quarter
Second Quarter
Third Quarter
Fourth Quarter

Holders of Record 

High

Low

67.92    $
71.44    $
81.26    $
81.45    $

High

Low

83.04    $
91.81    $
99.95    $
110.67    $

55.01 
61.21 
65.01 
70.10  

74.80 
78.07 
87.45 
94.28  

  $
  $
  $
  $

  $
  $
  $
  $

On February 12, 2018, we had approximately 46 stockholders of record as reported by our transfer agent. Holders of record are 

defined as those stockholders whose shares are registered in their names in our stock records and do not include beneficial owners of 
common stock whose shares are held in the names of brokers, dealers or clearing agencies.

Dividend Policy 

We do not currently intend to pay dividends on our common stock, and no dividends were declared or paid in 2017 or 2016. 

However, we expect to reevaluate our dividend policy on a regular basis and may, subject to compliance with the covenants contained 
in our credit facilities and other considerations, determine to pay dividends in the future. The declaration, amount and payment of any 
future dividends on shares of our common stock will be at the sole discretion of our Board, which may take into account general and 
economic conditions, our financial condition and results of operations, our available cash and current and anticipated cash needs, 
capital requirements, contractual, legal, tax and regulatory restrictions, the implications of the payment of dividends by us to our 
stockholders or by our subsidiaries to us, and any other factors that our Board may deem relevant. Our long-term debt arrangements 
contain usual and customary restrictive covenants that, among other things, place limitations on our ability to declare dividends. For 
additional information regarding these restrictive covenants, see Part II, Item 7 “Management’s Discussion and Analysis of Financial 
Condition and Results of Operations—Liquidity and Capital Resources” and Note 11 to our audited consolidated financial statements 
included elsewhere in this Annual Report on Form 10-K. 

Recent Sales of Unregistered Securities 

We did not sell any unregistered equity securities in 2017. 

41

  
 
 
 
 
 
 
    
 
  
 
 
 
 
 
 
 
    
 
  
Purchases of Equity Securities by the Issuer 

On October 30, 2013, our Board approved the repurchase program authorizing the repurchase of up to $125.0 million of either 
our common stock or vested in-the-money employee stock options, or a combination thereof (the “Repurchase Program”). Our Board 
increased the stock repurchase authorization under the Repurchase Program with respect to the repurchase of our common stock by 
$600.0 million, $1.5 billion, $1.0 billion and $1.0 billion in 2015, November 2016, February 2017 and May 2017, respectively, which 
increased the total amount that has been authorized under the Repurchase Program to $4.225 billion. The Repurchase Program does 
not obligate us to repurchase any particular amount of common stock or vested in-the-money employee stock options, and it may be 
modified, suspended or discontinued at any time. The timing and amount of repurchases are determined by our management based on 
a variety of factors such as the market price of our common stock, our corporate requirements, and overall market conditions. 
Purchases of our common stock may be made in open market transactions effected through a broker-dealer at prevailing market prices, 
in block trades, or in privately negotiated transactions. We may also repurchase shares of our common stock pursuant to a trading plan 
meeting the requirements of Rule 10b5-1 under the Exchange Act, which would permit shares of our common stock to be repurchased 
when we might otherwise be precluded from doing so by law. Repurchases of vested in-the-money employee stock options were made 
through transactions between us and our employees (other than our executive officers, who were not eligible to participate in the 
program), and this aspect of the Repurchase Program expired in November 2013. The Repurchase Program for common stock does 
not have an expiration date.

Since the Merger, we repurchased 43.7 million shares of our common stock at an average market price per share of $82.76 for 

an aggregate purchase price of $3,620 million both under and outside of the Repurchase Program. These amounts include 9,677,420 
shares of our common stock which we repurchased from certain of our principal stockholders in a private transaction for 
approximately $750 million and 10,071,003 shares of our common stock which we repurchased directly from underwriters in 
connection with three separate underwritten, secondary public offerings of shares of our common stock held by certain of our principal 
stockholders for approximately $935 million in the aggregate in May, September and November 2017. For additional information 
regarding our equity repurchases, see Part II, Item 7 “Management’s Discussion and Analysis of Financial Condition and Results of 
Operations—Liquidity and Capital Resources” and Note 14 to our audited consolidated financial statements included elsewhere in this 
Annual Report on Form 10-K. 

From inception of the Repurchase Program through December 31, 2017, we have repurchased a total of $4,043 million of our 

securities under the Repurchase Program consisting of $59 million of stock options and $3,984 million of common stock.  As of 
December 31, 2017, we have remaining authorization to repurchase up to $182 million of our common stock under the Repurchase 
Program. In addition, from time to time, we have repurchased and may continue to repurchase common stock through private or other 
transactions outside of the Repurchase Program. On February 14, 2018, the Board authorized an increase in the post-merger share 
repurchase authorization by $1.5 billion to a total of $5.0 billion, with $1.7 billion authorization remaining.

The following table summarizes the monthly equity repurchase program activity for the three months ended December 31, 

2017 and the approximate dollar value of shares that may yet be purchased pursuant to the Repurchase Program. In addition, the table 
includes shares repurchased outside the Repurchase Program and shares withheld from employees to satisfy certain tax obligations 
due in connection with grants of stock under the Quintiles IMS Holdings, Inc. 2017 Incentive and Stock Award Plan (“the Plan”). The 
Plan provides for the withholding of shares to satisfy tax obligations. It does not specify a maximum number of shares that can be 
withheld for this purpose. The shares of common stock withheld to satisfy tax withholding obligations may be deemed to be “issuer 
purchases” of shares that are required to be disclosed pursuant to this Item.

Period

October 1, 2017 – October 31, 2017
November 1, 2017 – November 30, 2017
December 1, 2017 – December 31, 2017

Total Number of
Shares Purchased(1)  

Average Price
Paid per Share

Total Number of
Shares Purchased as
Part of Publicly
Announced
Plans or Programs  

Approximate Dollar
Value of Shares That
May Yet Be Purchased
Under the 
Plans or Programs

(in millions, except per share data)

—    $
3.6    $
0.1    $
3.7     

—     
102.39     
99.06     

—    $
1.1    $
—    $
1.1     

295 
187 
182 

(1)   During the three months ended December 31, 2017, the Company repurchased 2.5 million shares outside the Repurchase program which were retired and 
approximately 0.1 million shares were withheld from employees to satisfy certain tax obligations due in connection with grants of stock under the Plan. 

42

 
 
 
 
 
 
 
 
 
 
   
   
   
 
   
      
  
During the year ended December 31, 2017, we repurchased 30.9 million shares of our common stock at an average market 

price per share of $84.80 for an aggregate purchase price of $2,620 million both under and outside of the Repurchase Program, which 
includes approximately 19.7 million shares from our sponsors.    

Stock Performance Graph 

This performance graph shall not be deemed “filed” for purposes of Section 18 of the Exchange Act, or incorporated by 
reference into any filing of IQVIA Holdings Inc. under the Exchange Act or under the Securities Act, except as shall be expressly set 
forth by specific reference in such filing.

The following graph shows a comparison from May 9, 2013 (the date our common stock commenced trading on the NYSE) 

through December 31, 2017 of the cumulative total return for our common stock, the Standard & Poor’s 500 Stock Index (“S&P 500”) 
and a select peer group. The peer group consists of Cerner Corporation, Charles River Laboratories, Inc., Dun & Bradstreet 
Corporation, Equifax Inc., ICON plc, IHS Markit Ltd., Laboratory Corporation of America Holdings, Nielsen N.V., PRA Health 
Sciences, Inc., Syneos Health (formerly INC Research Holdings), Thomson Reuters Corporation and Verisk Analytics, Inc. The 
companies in our peer group are publicly traded information services, information technology or contract research companies, and 
thus share similar business model characteristics to IQVIA, or provide services to similar customers as IQVIA. Many of these 
companies are also used by our compensation committee for purposes of compensation benchmarking.

The graph assumes that $100 was invested in IQVIA, the S&P 500 and the peer group as of the close of market on May 9, 

2013, assumes the reinvestments of dividends, if any. The S&P 500 and our peer group are included for comparative purposes only. 
They do not necessarily reflect management’s opinion that the S&P 500 and our peer group are an appropriate measure of the relative 
performance of the stock involved, and they are not intended to forecast or be indicative of possible future performance of our 
common stock.

5/9/2013

12/31/2013

12/31/2014

12/31/2015

12/31/2016

12/31/2017

IQVIA
Peer Group
S&P 500

  $
  $
  $

100    $
100    $
100    $

110    $
115    $
114    $

140    $
127    $
127    $

163    $
139    $
126    $

181    $
143    $
138    $

233 
163 
164  

43

 
 
 
   
   
   
   
   
 
Item 6. Selected Financial Data

We have derived the following consolidated statements of income data for 2017, 2016 and 2015 and consolidated balance 

sheet data as of December 31, 2017 and 2016 from our audited consolidated financial statements included elsewhere in this Annual 
Report on Form 10-K. We have derived the following consolidated statements of income data for 2014 and 2013 and consolidated 
balance sheet data as of December 31, 2015, 2014 and 2013 from our audited consolidated financial statements not included in this 
Annual Report on Form 10-K. You should read the consolidated financial data set forth below in conjunction with our consolidated 
financial statements and related notes included elsewhere in this Annual Report on Form 10-K and the information under Part II, 
Item 7, “Management’s Discussion and Analysis of Financial Condition and Results of Operations.” On October 3, 2016, we 
completed a merger of equals transaction with IMS Health. Pursuant to the terms of the merger agreement dated as of May 3, 2016 
between Quintiles and IMS Health, IMS Health was merged with and into Quintiles, and the separate corporate existence of IMS 
Health ceased, with Quintiles continuing as the surviving corporation. We have included the results of operations of acquired 
businesses, including IMS Health, from the date of acquisition. As a result, our period to period results of operations vary depending 
on the dates and sizes of the acquisitions. Accordingly, this selected financial data is not necessarily comparable or indicative of our 
future results. You should read this selected consolidated financial data in conjunction with our audited consolidated financial 
statements and related footnotes included elsewhere in this Annual Report on Form 10-K. 

(in millions, except per share data)
Statement of Income Data:
Revenues
Reimbursed expenses
Total revenues

Costs of revenue, exclusive of depreciation and
   amortization
Costs of revenue, reimbursed expenses
Selling, general and administrative expenses
Depreciation and amortization
Restructuring costs
Merger related costs(1)
Impairment charges(2)
Income from operations
Interest expense, net
Loss on extinguishment of debt
Other expense (income), net

Income before income taxes and equity in earnings
   (losses) of unconsolidated affiliates

Income tax (benefit) expense(3)

Income before equity in earnings (losses) of
   unconsolidated affiliates

Equity in earnings (losses) of unconsolidated affiliates

Net income

Net (income) loss attributable to non-controlling interests

Net income attributable to IQVIA Holdings Inc.

  $

Year Ended December 31,

2017

2016(4)

2015

2014

2013

  $

8,060    $
1,679     
9,739     

5,364    $
1,514     
6,878     

4,326    $
1,411     
5,737     

4,165    $
1,295     
5,460     

4,622     
1,679     
1,605     
1,011     
63     
—     
40     
719     
339     
19     
30     

331     
(987)    

1,318     
10     
1,328     
(19)    
1,309    $

3,236     
1,514     
1,011     
289     
71     
87     
28     
642     
140     
31     
(8)    

479     
345     

134     
(4)    
130     
(15)    
115    $

2,705     
1,411     
815     
128     
30     
—     
2     
646     
97     
8     
2     

539     
159     

380     
8     
388     
(1)    
387    $

2,664     
1,295     
781     
121     
9     
—     
—     
590     
97     
—     
(8)    

501     
149     

352     
5     
357     
—     
357    $

3,808 
1,291 
5,099 

2,452 
1,291 
772 
108 
14 
— 
— 
462 
119 
20 
— 

323 
96 

227 
(1)
226 
1 
227  

(in millions, except per share data)
Earnings per share attributable to common stockholders:
Basic
Diluted
Cash dividends declared per common share
Weighted average common shares outstanding:
Basic
Diluted

2017

Year Ended December 31,
2015

2014

2016(4)

2013

  $
  $
  $

6.01    $
5.88    $
—    $

0.77    $
0.76    $
—    $

3.15    $
3.08    $
—    $

2.78    $
2.72    $
—    $

1.83 
1.77 
— 

217.8     
222.6     

149.1     
152.0     

123.0     
125.6     

128.0     
131.1     

124.1 
127.9  

44

 
 
 
 
 
 
 
 
 
 
 
 
 
   
      
      
      
      
  
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
 
 
 
 
   
 
 
 
 
 
 
 
   
      
      
      
      
  
   
      
      
      
      
  
   
   
(in millions)
Statement of Cash Flow Data:
Net cash provided by (used in):

Operating activities
Investing activities
Financing activities
Other Financial Data:
Capital expenditures
Cash dividend paid to common stockholders

(in millions)
Balance Sheet Data:
Cash and cash equivalents
Investments in debt, equity and other securities
Trade accounts receivable and unbilled services, net
Property and equipment, net
Total assets
Total long-term liabilities
Total debt(5)
Total stockholders’ equity (deficit)

2017

Year Ended December 31,
2015

2014

2016(4)

2013

  $

  $

  $

970    $
(1,190)    
(72)    

860    $
1,731     
(2,284)    

(369)   $
—     

(164)   $
—     

476    $
(67)    
(249)    

(78)   $
—     

433    $
(173)    
(130)    

(83)   $
—     

393 
(236)
71 

(88)
—  

2017

2016(4)

As of December 31,
2015

2014

2013

959    $
54     
1,993     
440     
22,742     
11,480     
10,269     
8,358     

1,198    $
53     
1,707     
406     
21,208     
9,643     
7,219     
8,860     

977    $
33     
1,166     
188     
3,926     
2,668     
2,501     
(336)    

867    $
35     
975     
190     
3,296     
2,528     
2,306     
(704)    

777 
40 
924 
200 
3,054 
2,239 
2,061 
(667)

(1)   Merger related costs include the direct and incremental costs associated with our merger with IMS Health Holdings, Inc., on October 3, 2016 (the “Merger”). 
(2)  In 2017, we recognized $40 million of impairment losses for declines in fair value of goodwill ($39.6 million) and identifiable intangible assets ($0.4 million) in 

Encore, which we sold in the third quarter of 2017. In 2016, we recognized $28 million of impairment losses for declines in fair value of goodwill ($23 million) and 
identifiable intangible assets ($5 million) in Encore. In 2015, we wrote down $2 million related to long-lived assets. 

(3)  Income tax expense in 2017 includes $(977) million related to the enactment of the Tax Act and $(261) million related to purchase accounting amortization as a 
result of the Merger. Income tax expense in 2016 includes $252 million related to a change in our indefinitely reinvested assertion on our cumulative foreign 
earnings as a result of the Merger.

(4)  Includes the acquisition of IMS Health effective October 3, 2016. 
(5)  Excludes $44 million, $19 million, $33 million, $22 million and $28 million of unamortized discounts and debt issuance costs as of December 31, 2017, 2016, 

2015, 2014 and 2013. 

45

 
 
 
 
   
 
 
 
 
 
 
 
   
      
      
      
      
  
   
      
      
      
      
  
   
   
   
      
      
      
      
  
   
 
 
 
 
   
 
 
 
 
 
 
 
   
      
      
      
      
  
   
   
   
   
   
   
   
Item 7. Management’s Discussion and Analysis of Financial Condition and Results of Operations 

You should read the following discussion and analysis of our financial condition and results of operations together with our 

consolidated financial statements and the related notes included elsewhere in this Annual Report on Form 10-K. Some of the 
information contained in this discussion and analysis or set forth elsewhere in this Annual Report, including information with respect 
to our plans and strategy for our business, includes forward-looking statements that involve risks and uncertainties. You should read 
the “Risk Factors” section of this Annual Report for a discussion of important factors that could cause actual results to differ 
materially from the results described in or implied by the forward-looking statements contained in the following discussion and 
analysis. 

Overview 

We are a leading global provider of information, innovative technology solutions and contract research services focused on 

helping healthcare clients find better solutions for patients. Formed through the Merger of IMS Health and Quintiles, we apply human 
data science – leveraging the analytic rigor and clarity of data science to the ever-expanding scope of human science – to enable 
companies to reimagine and develop new approaches to clinical development and commercialization, speed innovation, and accelerate 
improvements in healthcare outcomes. Powered by the IQVIA CORE™, we deliver unique and actionable insights at the intersection 
of large scale analytics, transformative technology and extensive domain expertise, as well as execution capabilities to help biotech, 
medical device, and pharmaceutical companies, medical researchers, government agencies, payers and other healthcare stakeholders 
tap into a deeper understanding of diseases, human behaviors and scientific advances, in an effort to advance their path toward cures. 
With more than 55,000 employees, we conduct operations in more than 100 countries.

The Company is managed through three reportable segments, Commercial Solutions, Research & Development Solutions and 

Integrated Engagement Services. Commercial Solutions provides critical information, technology solutions and real-world insights 
and services to our life science clients. Research & Development Solutions, which primarily serves biopharmaceutical clients, is 
engaged in research and development and provides clinical research and clinical trial services. Integrated Engagement Services 
provides contract sales to both biopharmaceutical clients and the broader healthcare market. 

For a description of our service offerings within our segments, refer to “Business” within Part I, Item 1, of this Annual Report 

on Form 10-K. 

Industry Outlook 

For information about the industry outlook and markets that we operate in, refer to “Our Market Outlook” within Part I, Item I 

of this Annual Report on Form 10-K. 

Business Combinations 

We have completed and will continue to consider strategic business combinations to enhance our capabilities and offerings in 
certain areas, including several individually immaterial acquisitions during the years ended December 31, 2017 and 2016. In October 
2016, we completed the Merger to better serve our clients across their entire product lifecycle by (i) increasing the efficiency of 
healthcare companies’ commercial organizations through enhanced analytics and outsourcing services; (ii) improving clinical trial 
design, recruitment, and execution; and (iii) creating real-world information solutions based on the use of medicines by actual patients 
in normal situations. In July 2015, we combined our global clinical trials laboratory operations in our Research & Development 
Solutions segment with the clinical trials laboratory operations of Quest with the resulting combined business referred to as Q2 
Solutions. We own 60% of Q2 Solutions and Quest owns the remaining 40%. 

These transactions were accounted for as business combinations and the acquired results of operations are included in our 

consolidated financial information since the acquisition date with a non-controlling interest for the portion that we do not own. See 
Note 15 to our audited consolidated financial statements included elsewhere in this Annual Report on Form 10-K for additional 
information with respect to these business combinations. 

46

Sources of Revenue 

Total revenues are comprised of revenues from the provision of our services and revenues from reimbursed expenses that are 

incurred while providing our services. We do not have any material product revenues. Our segment revenues expressed as a percent of 
2017 revenues (excluding reimbursed expense revenue) are as follows: 

Commercial Solutions
Research & Development Solutions
Integrated Engagement Services

45.0%
45.3%
9.7%

Reimbursed expenses are comprised primarily of payments to physicians (investigators) who oversee clinical trials and travel 

expenses for our clinical monitors principally within our Research & Development Solutions segment and travel expenses for our 
sales representatives within our Integrated Engagement Services segment. Reimbursed expenses may fluctuate from period-to-period 
due, in part, to where we are in the lifecycle of the many contracts that are in progress at a particular point in time. As reimbursed 
expenses are pass-through costs to our clients with little to no profit and we believe that the fluctuations from period-to-period are not 
meaningful to our underlying performance, we do not provide any analysis of the fluctuations in these items or their impact on our 
financial results. We have collection risk on contractually reimbursable expenses, and, from time to time, are unable to obtain 
reimbursement from the client for costs incurred. When such an expense is not reimbursed, it is classified as costs of revenue on the 
consolidated statements of income. 

See Note 1 to our audited consolidated financial statements included elsewhere in this Annual Report on Form 10-K for details 

regarding the new revenue recognition standard, which will be effective January 1, 2018.

Costs and Expenses 

Our costs and expenses are comprised primarily of our costs of revenue, reimbursed expenses and selling, general and 
administrative expenses. Costs of revenue include compensation and benefits for billable employees and personnel involved in 
production, trial monitoring, data management and delivery, and the costs of acquiring and processing data for our information 
offerings; costs of staff directly involved with delivering technology-related services offerings and engagements, related 
accommodations and the costs of data purchased specifically for technology services engagements; and other expenses directly related 
to service contracts such as courier fees, laboratory supplies, professional services and travel expenses. As noted above, reimbursed 
expenses are comprised principally of payments to investigators who oversee clinical trials and travel expenses for our clinical 
monitors and sales representatives. Selling, general and administrative expenses include costs related to sales, marketing, and 
administrative functions (including human resources, legal, finance, quality assurance, compliance and general management) for 
compensation and benefits, travel, professional services, training and expenses for information technology (“IT”), facilities and 
depreciation and amortization. 

Foreign Currency Translation

In 2017, approximately 41% of our revenues were denominated in currencies other than the United States dollar, which 

represents approximately 55 currencies. Because a large portion of our revenues and expenses are denominated in currencies other 
than the United States dollar and our financial statements are reported in United States dollars, changes in foreign currency exchange 
rates can significantly affect our results of operations. The revenue and expenses of our foreign operations are generally denominated 
in local currencies and translated into United States dollars for financial reporting purposes. Accordingly, exchange rate fluctuations 
will affect the translation of foreign results into United States dollars for purposes of reporting our consolidated results. As a result, we 
believe that providing the impact of fluctuations in foreign currency rates on certain financial results can facilitate the analysis of 
period-to-period comparisons of business performance that excludes the effects of foreign currency rate fluctuations. The constant 
currency information assumes the same foreign currency exchange rates that were in effect for the comparable prior-year period were 
used in translation of the current period results. 

47

 
 
 
 
 
 
Consolidated Results of Operations 

 For information regarding our results of operations for Commercial Solutions, Research & Development Solutions and 

Integrated Engagement Services, refer to “Segment Results of Operations” later in this section.

Revenues 

(dollars in millions)
Revenues

  $

2017 compared to 2016 

Year Ended December 31,
2016
5,364    $

2017
8,060    $

2015
4,326    $

Change

2017 vs. 2016

2016 vs. 2015

  %  

$
2,696     

50.3%  $

$
1,038     

  %  

24.0%

In 2017, our revenues increased $2,696 million, or 50.3%, as compared to the same period in 2016. This increase was 
comprised of constant currency revenue growth of approximately $2,678 million, or 49.9%, and a positive impact of approximately 
$18 million from the effects of foreign currency fluctuations. The constant currency revenue growth was comprised of a $2,515 
million increase in Commercial Solutions, which includes $2,557 million from the Merger, partially offset by lower revenue from 
Encore during the first half of 2017 and the sale of Encore at the beginning of the third quarter of 2017, a $172 million increase in 
Research & Development Solutions and a $9 million decrease in Integrated Engagement Services.

2016 compared to 2015

In 2016, our revenues increased $1,038 million, or 24.0%, as compared to the same period in 2015. This increase was 
comprised of constant currency revenue growth of approximately $1,044 million, or 24.1%, and a negative impact of approximately 
$6 million from the effects of foreign currency fluctuations. The constant currency revenue growth was comprised of a $769 million 
increase in Commercial Solutions, which includes $799 million from the Merger, partially offset by a decline in the legacy service 
offerings, a $341 million increase in Research & Development Solutions, which includes the incremental impact from the businesses 
that Quest contributed to Q2 Solutions, and a $66 million decrease in Integrated Engagement Services. The revenue contributed by the 
Merger in 2016 was negatively impacted by approximately $55 million as a result of adjusting the acquired IMS Health unearned 
income to fair value as required by purchase accounting. 

Costs of Revenue, exclusive of Depreciation and Amortization 

(dollars in millions)
Costs of revenue, exclusive of depreciation and amortization
% of revenues

2017 compared to 2016

2017

Year Ended December 31,
2016

2015

  $

4,622 
  $
57.3%   

3,236 
  $
60.3%   

2,705 
62.5%

When compared to 2016, costs of revenue, exclusive of depreciation and amortization, in 2017 increased $1,386 million. This 

increase includes a constant currency increase of approximately $1,388 million, or 42.9%, partially offset by a positive impact of 
approximately $2 million from the effects of foreign currency fluctuations. The constant currency growth was comprised of a $1,267 
million increase in Commercial Solutions, which includes $1,302 million from the Merger, partially offset by lower costs from Encore 
during the first half of 2017 and the sale of Encore at the beginning of the third quarter of 2017, a $119 million increase in Research & 
Development Solutions and a $2 million increase in Integrated Engagement Services.

As a percent of revenues, costs of revenue declined in 2017 to 57.3% as compared to 60.3% in 2016. This decline was 

primarily due to the fact that 2017 includes a lower proportion of revenues from the lower margin Integrated Engagement Services 
segment, primarily as a result of the Merger.

48

 
  
 
 
  
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
2016 compared to 2015 

When compared to 2015, costs of revenue, exclusive of depreciation and amortization, in 2016 increased $531 million. This 

increase includes a constant currency increase of approximately $566 million, or 20.9%, partially offset by a positive impact of 
approximately $35 million from the effects of foreign currency fluctuations. The constant currency growth was comprised of a $403 
million increase in Commercial Solutions, which includes $435 million from the Merger, partially offset by a decline in the legacy 
service offerings, a $222 million increase in Research & Development Solutions, which includes the incremental impact from the 
businesses that Quest contributed to Q2 Solutions, and a $59 million decrease in Integrated Engagement Services.  

Selling, General and Administrative Expenses

(dollars in millions)
Selling, general and administrative expenses
% of revenues

2017 compared to 2016

2017

Year Ended December 31,
2016

2015

  $

1,605 
  $
19.9%   

1,011 
  $
18.8%   

815 
18.8%

The $594 million increase in selling, general and administrative expenses in 2017 includes a constant currency increase of 
$587 million, or 58.1%, and a negative impact of approximately $7 million from the effects of foreign currency fluctuations. The 
constant currency growth primarily consisted of a $479 million increase in Commercial Solutions, primarily from the Merger and a $6 
million increase in Research & Development Solutions.  Also contributing to the increase was a higher level of general corporate and 
unallocated expenses of $111 million, primarily due to higher stock-based compensation expense and acquisition and integration 
related costs, which was partially offset by a $9 million decrease in Integrated Engagement Services.

2016 compared to 2015 

The $196 million increase in selling, general and administrative expenses in 2016 includes a constant currency increase of 

$215 million, or 26.4%, partially offset by a positive impact of approximately $19 million from the effects of foreign currency 
fluctuations. The constant currency growth was comprised of a $149 million increase in Commercial Solutions, which includes $156 
million from the Merger, partially offset by a decline in legacy service offerings, a $34 million increase in Research & Development 
Solutions, which includes the incremental impact from the businesses that Quest contributed to Q2 Solutions, a $3 million increase in 
Integrated Engagement Services, and a $29 million increase in general corporate and unallocated expenses, which includes $37 
million from the Merger. The constant currency increase in general corporate and unallocated expenses in 2016 was primarily due to 
higher stock-based compensation expense. 

Depreciation and Amortization 

(dollars in millions)
Depreciation and amortization
% of revenues

2017

Year Ended December 31,
2016

2015

  $

1,011 
  $
12.5%   

289 
  $
5.4%   

128 
3.0%

The $722 million and $161 million increases in depreciation and amortization in 2017 and 2016, respectively, were primarily 

due to the approximately $6.4 billion of intangible assets acquired in the Merger.

49

 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
   
Restructuring Costs 

(in millions)
Restructuring costs

2017

Year Ended December 31,
2016

2015

  $

63    $

71    $

30  

During 2017, we recognized $63 million of restructuring charges, net of reversals for changes in estimates, under our existing 
restructuring plans. The remaining actions under these plans, as well as actions associated with upcoming 2018 plans, are expected to 
occur throughout 2018, and are expected to consist of severance, facility closure and other exit-related costs. 

During 2016, we recognized $71 million of restructuring charges, net of reversals for changes in estimates, under our existing 

restructuring plans. 

During 2015, we recognized $30 million of restructuring charges, net of reversals for changes in estimates, associated with 

both the February 2015 restructuring plan and the Q2 Solutions restructuring plan. 

Merger Related Costs 

(in millions)
Merger related costs

2017

Year Ended December 31,
2016

2015

  $

—    $

87    $

—  

During 2016, we recognized $87 million of merger related costs. Merger related costs include the direct and incremental costs 
associated with the Merger such as (i) investment banking, legal, accounting and consulting fees, (ii) incremental compensation costs 
triggered under change in control provisions in executive employment agreements, (iii) compensation and related costs of employees 
100% dedicated to merger-related integration activities and (iv) severance and other termination costs associated with employees 
whose positions became redundant as a result of the Merger.  

Impairment Charges 

(in millions)
Impairment charges

2017

Year Ended December 31,
2016

2015

  $

40    $

28    $

2  

During 2017 and 2016, we recognized $40 million and $28 million, respectively, of impairment losses for declines in fair 

value of goodwill and identifiable intangible assets in Encore. See Note 17 to our audited consolidated financial statements included 
elsewhere in this Annual Report on Form 10-K for additional information with respect to impairment charges. During the fourth 
quarter of 2015, we exited a training facility in Japan, resulting in a $2 million impairment of the land and building. 

Interest Income and Interest Expense 

(in millions)
Interest income
Interest expense

2017

Year Ended December 31,
2016

2015

  $
  $

(7)   $
346    $

(4)   $
144    $

(4)
101  

Interest income includes interest received primarily from bank balances and investments. 

Interest expense during 2017 was higher than 2016 due to an increase in the average debt outstanding, primarily as a result of 

the debt assumed in the Merger and the refinancing transaction in the fourth quarter of 2016 (approximately $4.5 billion), the February 
2017 issuance of €1,425 million (approximately $1,522 million) of 3.25% senior notes, the September 2017 issuance of €420 million 
(approximately $501 million) of 2.875% senior notes and the incremental term B loan of $750 million. See Note 11 to our audited 
consolidated financial statements included elsewhere in this Annual Report on Form 10-K for additional information with respect to 
these debt transactions. Interest expense during 2016 was higher than 2015 due to an increase in the average debt outstanding, 
primarily as a result of the debt acquired from the Merger. 

50

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Loss on Extinguishment of Debt 

(in millions)
Loss on extinguishment of debt

2017

Year Ended December 31,
2016

2015

  $

19    $

31    $

8  

During 2017, we recognized a $19 million loss on extinguishment of debt for fees and expenses incurred related to the 

refinancing of our senior notes and senior secured credit facilities, which includes a $16 million make-whole premium. 

In the fourth quarter of 2016, we recognized a $31 million loss on extinguishment of debt related to the refinancing of our 

senior secured credit facilities. The loss on extinguishment of debt includes an $8 million make-whole premium, $9 million of 
unamortized debt issuance costs and $14 million of unamortized discount. 

In May 2015, we recognized an $8 million loss on extinguishment of debt related to the refinancing of our senior secured 
credit facilities. The loss on extinguishment of debt includes $1 million of unamortized debt issuance costs, $1 million of unamortized 
discount and $6 million of related fees and expenses. 

See “—Liquidity and Capital Resources” for more information on these transactions.  

Other Expense (Income), Net 

(in millions)
Other expense (income), net

2017

Year Ended December 31,
2016

2015

  $

30    $

(8)   $

2  

Other expense, net for 2017 primarily consisted of foreign currency net losses, partially offset by investment gains. The 
foreign currency losses in 2017 were primarily the result of the combination of changes in intercompany loan balances from corporate 
legal entity integration and a weaker U.S. dollar.

Other income, net for 2016 primarily consisted of a gain on the sale of a cost basis investment partially offset by foreign 

currency net losses.  

Other expense, net for 2015 primarily consisted of $6 million of expense related to the change in fair value of contingent 

consideration related to an acquisition, partially offset by $5 million of foreign currency net gains. 

Income Tax (Benefit) Expense

(dollars in millions)
Income tax (benefit) expense
Effective income tax rate

2017

Year Ended December 31,
2016

2015

  $

(987)

  $
(298.2)%   

345 
  $
72.0%   

159 
29.5%

On December 22, 2017, the U.S. government enacted the Tax Act. The Tax Act is comprehensive legislation that includes 

provisions that lower the federal corporate income tax rate from 35% to 21% beginning in 2018 and impose a one-time transition tax 
on undistributed foreign earnings. ASC 740 “Income Taxes” generally requires the effects of the tax law change to be recorded in the 
period of enactment. However, the SEC staff issued Staff Accounting Bulletin No. 118 to address situations when a registrant does not 
have the necessary information available, prepared, or analyzed (including computations) in reasonable detail to complete the 
accounting for certain income tax effects of the Tax Act. We have recognized the tax impacts related to the transition tax on 
undistributed foreign earnings and the impact to deferred tax assets and liabilities and included these amounts in our consolidated 
financial statements for the year ended December 31, 2017, on a provisional basis. The ultimate impact may differ from these 
provisional amounts, possibly materially, due to, among other things, additional analysis, changes in interpretations and assumptions 
we have made, and additional interpretive regulatory guidance that may be issued. The accounting is expected to be complete when 
the 2017 U.S. corporate income tax return is filed in 2018.  

51

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
As a result of the Tax Act, we recorded a provisional deferred tax benefit of $977 million related to the revaluation of deferred 

taxes at the newly enacted 21% rate and the reversal of the deferred tax liability on undistributed foreign earnings net of the newly 
enacted transition tax. We no longer consider any of our foreign earnings to be indefinitely reinvested. Our effective income tax rate 
was also favorably impacted by a tax benefit of $261 million related to purchase accounting amortization of approximately $763 
million as a result of the Merger. Additionally, due to the adoption of the new stock-based compensation accounting standard on 
January 1, 2017, our effective income tax rate was favorably impacted by $26 million of excess tax benefits on equity compensation.

The increase in the 2016 effective income tax rate, as compared to 2015, was due to a change in our indefinite reinvestment 

assertion on the majority of our cumulative foreign earnings. Due to the Merger, we reevaluated our indefinite reinvestment assertion 
based on the need for cash in the United States, including funding the Repurchase Program and potential acquisitions. Accordingly, 
we changed our assertion with respect to $2,801 million of foreign earnings, including $1,865 million of IMS Health’s previously 
undistributed historical foreign earnings. Deferred income taxes of $625 million were recorded in 2016 related to non-indefinitely 
reinvested foreign earnings. Of that amount, $373 million was recorded through purchase accounting related to IMS Health’s 
historical foreign earnings and the remainder of $252 million was recorded through deferred income tax expense 

Equity in Earnings (Losses) of Unconsolidated Affiliates 

(in millions)
Equity in earnings (losses) of unconsolidated affiliates

2017

Year Ended December 31,
2016

2015

  $

10    $

(4)   $

8  

Equity in earnings (losses) of unconsolidated affiliates primarily includes earnings (losses) from our investment in NovaQuest 
Pharma Opportunities Funds. See Note 4 to our audited consolidated financial statements included elsewhere in this Annual Report on 
Form 10-K for additional information with respect to these funds.

Net Income Attributable to Non-controlling Interests 

(in millions)
Net income attributable to non-controlling interests

2017

Year Ended December 31,
2016

2015

  $

(19)   $

(15)   $

(1)

Net income attributable to non-controlling interests primarily includes Quest’s interest in Q2 Solutions. 

Segment Results of Operations 

Revenues and profit by segment are as follows (dollars in millions): 

Commercial Solutions
Research & Development Solutions
Integrated Engagement Services
Total
General corporate and unallocated
Depreciation and amortization
Restructuring costs
Merger related costs
Impairment charges
Consolidated

Segment Revenues
2016

2017

2015

2017

Segment Profit
2016

2015

  $

3,630    $
3,647     
783     
8,060     

1,089    $
3,478     
797     
5,364     

323    $
3,159     
844     
4,326     

  $

8,060    $

5,364    $

4,326    $

1,010    $
997     
73     
2,080     
(247)    
(1,011)    
(63)    
—     
(40)    
719    $

234    $
943     
76     
1,253     
(136)    
(289)    
(71)    
(87)    
(28)    
642    $

19 
824 
78 
921 
(115)
(128)
(30)
— 
(2)
646  

Prior period segment results have been recast to conform to immaterial changes to management reporting in 2017. The recast 
only impacts the fourth quarter of 2016 as the management reporting changes relate to IMS Health and these results are only reflected 
in our results since the date of the Merger on October 3, 2016.  

52

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
      
      
      
   
      
      
      
   
      
      
      
   
      
      
      
   
      
      
      
Certain costs are not allocated to our segments and are reported as general corporate and unallocated expenses. These costs 

primarily consist of stock-based compensation, and expenses for corporate overhead functions such as senior leadership, finance, 
human resources, information technology, facilities and legal. In addition, we do not allocate depreciation and amortization, 
restructuring costs, merger related costs or impairment charges to our segments.  

Commercial Solutions 

(dollars in millions)
Revenues
Costs of revenue, exclusive of depreciation
   and amortization
Selling, general and administrative expenses
Segment profit

  $

  $

Revenues 

2017 compared to 2016

Year Ended December 31,
2016
1,089    $

2017
3,630    $

2015

323    $

Change

2017 vs. 2016
2,541     

233.3%  $

2016 vs. 2015
766     

237.2%

1,917     
703     
1,010    $

641     
214     
234    $

239     
65     
19    $

1,276     
489     
776     

199.1 
228.5 
331.6%  $

402     
149     
215      1,131.6%

168.2 
229.2 

Commercial Solutions’ revenues were $3,630 million in 2017, an increase of $2,541 million over 2016. This increase was 

comprised of constant currency revenue growth of approximately $2,515 million, and a positive impact of approximately $26 million 
from the effects of foreign currency fluctuations. The constant currency increase includes the incremental impact from the Merger of 
$2,557 million, including post-Merger acquisitions, partially offset by a decline in revenue from Encore during the first half of 2017 
and the sale of Encore at the beginning of the third quarter of 2017. 

2016 compared to 2015 

Commercial Solutions’ revenues were $1,089 million in 2016, an increase of $766 million over 2015, which includes the 

impact from the Merger of $799 million. The revenue increase was due to the impact from the Merger and from growth in real-world 
and late phase research services, partially offset by lower revenues from Encore and advisory services. The revenue contributed by the 
Merger in 2016 was negatively impacted by approximately $55 million as a result of adjusting the acquired IMS Health unearned 
income to fair value as required by purchase accounting. 

Costs of Revenue, exclusive of Depreciation and Amortization 

2017 compared to 2016 

Commercial Solutions’ costs of revenues, exclusive of depreciation and amortization, were $1,917 million in 2017, an increase 

of $1,276 million over 2016. This increase was comprised of a $1,267 million constant currency increase and a negative impact of 
approximately $9 million from the effects of foreign currency fluctuations. The constant currency increase includes the incremental 
impact from the Merger of $1,302 million, including post-Merger acquisitions, partially offset by lower costs from Encore due to 
lower revenue volumes during the first half of 2017 and the sale of Encore at the beginning of the third quarter of 2017.

2016 compared to 2015 

Commercial Solutions’ costs of revenue, exclusive of depreciation and amortization, increased approximately $402 million in 
2016. This increase was comprised of a $403 million constant currency increase, which includes $435 million from the Merger, offset 
by lower costs from Encore and advisory services due to lower revenue volumes, and $1 million due to the negative effects of foreign 
currency fluctuations.  

53

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
Selling, General and Administrative Expenses

2017 compared to 2016 

Commercial Solutions’ selling, general and administrative expenses increased approximately $489 million in 2017 as 
compared to 2016. This increase was comprised of a $479 million constant currency increase and a negative impact of approximately 
$10 million from the effects of foreign currency fluctuations. The constant currency increase was primarily due to the incremental 
impact from the Merger of $487 million, including post-Merger acquisitions. 

2016 compared to 2015 

Commercial Solutions’ selling, general and administrative expenses increased approximately $149 million in 2016 as 

compared to 2015. This increase was primarily due to $156 million from the Merger, an increase in bad debt expense and partially 
offset by cost reductions in various other areas. 

Research & Development Solutions 

(dollars in millions)
Revenues
Costs of revenue, exclusive of depreciation
   and amortization
Selling, general and administrative expenses
Segment profit

  $

  $

Backlog and Net New Business 

Year Ended December 31,
2016
3,478    $

2017
3,647    $

2015
3,159    $

2017 vs. 2016
169     

2,068     
582     
997    $

1,956     
579     
943    $

1,779     
556     
824    $

112     
3     
54     

Change

4.9%  $

5.7 
0.5 
5.7%  $

2016 vs. 2015
319     

10.1%

177     
23     
119     

9.9 
4.1 
14.4%

Beginning with the third quarter of 2016, we began reporting net new business and backlog on an as-contracted basis (signed 

binding commitments and signed contracts during the period) on a rolling basis for the last twelve months. We only report backlog 
and net new business for the Research & Development Solutions segment. Previously, net new business included non-binding written 
awards, which was consistent with industry practice. We believe the as-contracted method is a more precise approach as it requires a 
higher threshold and less judgment for backlog inclusion. Net new business totaled $4.54 billion and $4.34 billion for the twelve 
months ended December 31, 2017 and 2016, respectively. Ending backlog was $10.54 billion at December 31, 2017. 

Net new business under sole provider arrangements is recorded over the life of the arrangement as projects are awarded. 

Consistent with our methodology for calculating net new business during a particular period, backlog represents, at a particular point 
in time, future service revenues from work not yet completed or performed under signed contracts. Once work begins on a project, 
service revenues are recognized over the duration of the project. Net new business and backlog denominated in foreign currencies are 
valued each month using the actual average foreign exchange rates in effect during the month. 

 We believe that backlog and net new business may not be consistent indicators of future revenues because they have been and 
likely will be affected by a number of factors, including the variable size and duration of projects, many of which are performed over 
several years, cancellations, and changes to the scope of work during the course of projects. Projects that have been delayed remain in 
backlog, but the timing of the revenue generated may differ from the timing originally expected. Additionally, projects may be 
terminated or delayed by the customer or delayed by regulatory authorities. In the event that a client cancels a contract, we typically 
would be entitled to receive payment for all services performed up to the cancellation date and subsequent client-authorized services 
related to winding down the canceled project. For more details regarding risks related to our backlog, see Part I, Item IA, “Risk 
Factors—Risks Related to our Business—The relationship of backlog to revenues varies over time.”

54

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
Revenues 

2017 compared to 2016 

Research & Development Solutions’ revenues were $3,647 million in 2017, an increase of $169 million, or 4.9%, over 2016. 

This increase was comprised of constant currency revenue growth of $172 million, or 4.9%, partially offset by a negative impact of 
approximately $3 million from the effects of foreign currency fluctuations.

The constant currency revenue growth for 2017 primarily includes volume-related increases from both our clinical solutions 

and services and our clinical trial support services as well as revenue from current year acquisitions, partially offset by lower revenue 
from early clinical development services, due to a facility closure in Europe in 2016.

 2016 compared to 2015 

Research & Development Solutions’ revenues were $3,478 million in 2016, an increase of $319 million, or 10.1%, over 2015. 

This increase was comprised of constant currency revenue growth of $341 million, or 10.8%, partially offset by a negative impact of 
approximately $22 million from the effects of foreign currency fluctuations. The constant currency revenue growth primarily includes 
volume-related increases in our services and the incremental impact from the businesses that Quest contributed to Q2 Solutions. 

The volume-related revenue growth was related to increases in revenue from both our clinical solutions and services and our 

clinical trial support services. This growth was due largely to execution on the higher backlog in place as we entered the year. The 
2016 growth was negatively impacted by $17 million of non-recurring revenue recognized in the second quarter of 2015 related to the 
early close out of a client arrangement. The constant currency revenue growth in 2016 was negatively impacted by $27 million of 
foreign currency exchange rate adjustments associated with client contracts and losses on foreign exchange forward contracts. 

Costs of Revenue, exclusive of Depreciation and Amortization 

2017 compared to 2016 

Research & Development Solutions’ costs of revenue, exclusive of depreciation and amortization, increased approximately 

$112 million in 2017 as compared to 2016. This increase includes constant currency growth of $119 million, or 6.1%, partially offset 
by $7 million from the positive effects of foreign currency fluctuations.

The constant currency costs of revenue growth was primarily due to an increase in compensation and related expenses and the 

impact from post-Merger acquisitions. The increase in compensation and related expenses resulted from (i) an increase in billable 
headcount resulting from the higher volume of constant currency revenue, (ii) our continued investment in our global delivery network 
(“GDN”) that enables us to provide standardized, centrally-managed services from seven hub locations across five countries, and 
(iii) an increase in competition for qualified personnel in certain markets.

 2016 compared to 2015 

Research & Development Solutions’ costs of revenue, exclusive of depreciation and amortization, increased approximately 

$177 million in 2016 over 2015. This increase includes constant currency growth of $222 million, or 12.5%, which includes the 
incremental impact from the businesses that Quest contributed to Q2 Solutions, partially offset by $45 million from the positive effects 
of foreign currency fluctuations.  

The constant currency costs of revenue growth was primarily due to the impact from the Q2 Solutions transaction and an 

increase in compensation and related expenses. The increase in compensation and related expenses resulted from (i) an increase in 
billable headcount resulting from the higher volume of constant currency revenue, (ii) our continued investment in our GDN which is 
a coordinated global delivery model that enables us to provide standardized, centrally-managed services from seven hub locations 
across five countries, (iii) annual merit increases and (iv) an increase in competition for qualified personnel in certain markets. The 
constant currency growth for 2016 also includes a $12 million reserve for certain potentially non-reimbursable expenses. These 
increases in cost were partially offset by $17 million of expense recognized in the second quarter of 2015 related to the early close out 
of a client arrangement that did not recur in 2016 and a $15 million increase in the benefit from research and development credits 
received in Europe. 

55

Selling, General and Administrative Expenses

2017 compared to 2016 

Research & Development Solutions’ selling, general and administrative expenses increased approximately $3 million, or 
0.5%, in 2017 as compared to 2016. This increase was caused by a constant currency increase of $6 million, offset by a positive 
impact of approximately $3 million from the effects of foreign currency fluctuations. As a percent of revenues, Research & 
Development Solutions’ selling, general and administrative expenses were 16.0% and 16.6% in 2017 and 2016, respectively. The 
constant currency increase for 2017 was primarily due to the impact of post-Merger acquisitions, partially offset by lower incentive 
compensation and bad debt expense. 

2016 compared to 2015 

Research & Development Solutions’ selling, general and administrative expenses increased approximately $23 million, or 

4.1%, in 2016 as compared to 2015. This increase was caused by constant currency growth of $34 million, partially offset by a 
reduction of $11 million from foreign currency fluctuations. As a percent of revenues, Research & Development Solutions’ selling, 
general and administrative expenses were 16.6% and 17.6% in 2016 and 2015, respectively. The constant currency increase was 
primarily due to the incremental impact from the businesses that Quest contributed to Q2 Solutions, higher compensation and related 
expenses due to annual merit increases and an increase in headcount and an increase in bad debt expense.  

Integrated Engagement Services 

(dollars in millions)
Revenues
Costs of revenue, exclusive of depreciation
   and amortization
Selling, general and administrative expenses
Segment profit

Revenues 

2017 compared to 2016 

Year Ended December 31,
2016

2015

2017

  $

783    $

797    $

844    $

Change

2017 vs. 2016
(14)    

(1.8)%  $

2016 vs. 2015
(47)    

(5.6)%

637     
73     
73    $

639     
82     
76    $

687     
79     
78    $

(2)    
(9)    
(3)    

(0.3)
(11.0)
(3.9)%  $

(48)    
3     
(2)    

(7.0)
3.8 
(2.6)%

  $

Integrated Engagement Services’ revenues were $783 million in 2017, a decrease of $14 million, or 1.8%, over 2016. This 

decrease was comprised of a constant currency revenue decrease of $9 million, or 1.1%, and a negative impact of approximately $5 
million due to the effects of foreign currency fluctuations. The decline in constant currency revenues for 2017 was due to lower 
demand in Japan and North America, which was also a result of cancellations that occurred in 2017. The decline was also due to a $9 
million benefit from the acceleration of revenue in the second quarter of 2016 that did not recur in 2017 related to a contract 
modification on a sales force arrangement that fixed a portion of the contract price that was previously not determinable until future 
sales-based royalties were known, partially offset by revenue from new projects starting up, primarily in Europe. 

2016 compared to 2015 

Integrated Engagement Services’ revenues were $797 million in 2016, a decrease of $47 million, or 5.6%, over 2015. This 

decrease was comprised of a constant currency revenue decrease of $66 million, or 7.8%, partially offset by a positive impact of 
approximately $19 million due to the effects of foreign currency fluctuations. The decline in constant currency revenues for 2016 was 
due to decreases in North America (primarily as a result of cancellations that occurred in 2015 and earlier this year), Japan and 
Europe. The decline in Europe was partially offset by a $9 million benefit from the acceleration of revenue related to a contract 
modification in 2016.

56

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
Costs of Revenue, exclusive of Depreciation and Amortization 

2017 compared to 2016 

Integrated Engagement Services’ costs of revenue, exclusive of depreciation and amortization, decreased approximately $2 

million in 2017. This decrease includes constant currency growth of $2 million, or 0.3%, more than offset by $4 million from the 
positive effects of foreign currency fluctuations. The constant currency cost of revenue growth in 2017 was due to an increase in 
compensation and related expenses resulting from an increase in billable headcount in Europe as a result of an increase in new projects 
starting up in the 2017 period.

 2016 compared to 2015 

Integrated Engagement Services’ costs of revenue, exclusive of depreciation and amortization, decreased approximately $48 

million in 2016. This decrease was comprised of a $59 million constant currency decrease, or 8.6%, partially offset by $11 million due 
to the positive effects of foreign currency fluctuations. The constant currency decrease for 2016 was due to a decrease in 
compensation and related expenses resulting from a decrease in billable headcount. 

Selling, General and Administrative Expenses

2017 compared to 2016 

Integrated Engagement Services’ selling, general and administrative expenses decreased approximately $9 million in 2017 as 

compared to 2016, primarily due to lower compensation and related expenses resulting from a decrease in headcount.

2016 compared to 2015 

Integrated Engagement Services’ selling, general and administrative expenses increased approximately $3 million in 2016 as 

compared to 2015, primarily due to a higher level of bad debt expense. 

57

Liquidity and Capital Resources 

Overview 

We assess our liquidity in terms of our ability to generate cash to fund our operating, investing and financing activities. Our 

principal source of liquidity is operating cash flows. In addition to operating cash flows, other significant factors that affect our overall 
management of liquidity include: capital expenditures, acquisitions, investments, debt service requirements, dividends, equity 
repurchases, adequacy of our revolving credit and receivables financing facilities and access to the capital markets. 

We manage our worldwide cash requirements by monitoring the funds available among our subsidiaries and determining the 

extent to which those funds can be accessed on a cost-effective basis. The repatriation of cash balances from certain of our subsidiaries 
could have adverse tax consequences; however, those balances are generally available without legal restrictions to fund ordinary 
business operations. We have and expect to transfer cash from those subsidiaries to the United States and to other international 
subsidiaries when it is cost effective to do so. 

We had a cash balance of $959 million at December 31, 2017 ($147 million of which was in the United States), a decrease 

from $1,198 million at December 31, 2016. 

Based on our current operating plan, we believe that our available cash and cash equivalents, future cash flows from operations 

and our ability to access funds under our revolving credit and receivables financing facilities will enable us to fund our operating 
requirements and capital expenditures and meet debt obligations for at least the next 12 months. We regularly evaluate our debt 
arrangements, as well as market conditions, and from time to time we may explore opportunities to modify our existing debt 
arrangements or pursue additional financing arrangements that could result in the issuance of new debt securities by us or our 
affiliates. We may use our existing cash, cash generated from operations or dispositions of assets or businesses and/or proceeds from 
any new financing arrangements or issuances of debt or equity securities to repay or reduce some of our outstanding obligations, to 
repurchase shares from our stockholders or for other purposes. As part of our ongoing business strategy, we also continually evaluate 
new acquisition, expansion and investment possibilities or other strategic growth opportunities, as well as potential dispositions of 
assets or businesses, as appropriate, including dispositions that may cause us to recognize a loss on certain assets. Should we elect to 
pursue any such transaction, we may seek to obtain debt or equity financing to facilitate those activities. Our ability to enter into any 
such potential transactions and our use of cash or proceeds is limited to varying degrees by the terms and restrictions contained in our 
existing debt arrangements. We cannot provide assurances that we will be able to complete any such financing arrangements or other 
transactions on favorable terms or at all. 

Equity Repurchase Program

On October 30, 2013, our Board approved the Repurchase Program authorizing the repurchase of up to $125 million of either 

our common stock or vested in-the-money employee stock options, or a combination thereof. Our Board increased the stock 
repurchase authorization under the Repurchase Program with respect to the repurchase of our common stock by $600 million, $1.5 
billion, $1.0 billion and $1.0 billion in 2015, November 2016, February 2017 and May 2017, respectively, which increased the total 
amount that has been authorized under the Repurchase Program to $4.225 billion. The Repurchase Program does not obligate us to 
repurchase any particular amount of common stock or vested in-the-money employee stock options, and it may be modified, 
suspended or discontinued at any time. The timing and amount of repurchases are determined by our management based on a variety 
of factors such as the market price of our common stock, our corporate requirements, and overall market conditions. Purchases of our 
common stock may be made in open market transactions effected through a broker-dealer at prevailing market prices, in block trades, 
or in privately negotiated transactions. We may also repurchase shares of our common stock pursuant to a trading plan meeting the 
requirements of Rule 10b5-1 under the Exchange Act, which would permit shares of our common stock to be repurchased when we 
might otherwise be precluded from doing so by law. The Repurchase Program for common stock does not have an expiration date.

During the year ended December 31, 2017, we repurchased 30,896,313 shares of our common stock for approximately $2.6 

billion. These amounts include 9,677,420 shares of our common stock, which we repurchased from certain of our principal 
stockholders in a private transaction for approximately $750 million and 10,071,003 shares of our common stock, which we 
repurchased directly from underwriters in connection with three separate underwritten, secondary public offerings of shares of our 
common stock held by certain of our principal stockholders for approximately $935 million in the aggregate in May, September and 
November 2017. Additional information regarding the Repurchase Program is presented in Part II, Item 5 “Market for Registrant’s 
Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities” and Notes 14 and 27 to our audited 
consolidated financial statements included elsewhere in this Annual Report on Form 10-K.

58

As of December 31, 2017, we have remaining authorization to repurchase up to $182 million of our common stock under the 

Repurchase Program. In addition, from time to time, we have repurchased and may continue to repurchase common stock through 
private or other transactions outside of the Repurchase Program. On February 14, 2018, the Board authorized an increase in the post-
merger share repurchase authorization by $1.5 billion to a total of $5.0 billion, with $1.7 billion authorization remaining.

Debt

As of December 31, 2017, we had $10.3 billion of total indebtedness, excluding $500 million of available borrowings under 
our revolving credit facilities. See Note 11 to our audited consolidated financial statements included elsewhere in this Annual Report 
on Form 10-K for additional details regarding our credit arrangements.

Senior Secured Credit Agreement and Senior Notes

2017 Financing Transactions

At December 31, 2017, our senior secured credit facility provided financing of up to approximately $5,656 million, which 

consisted of $5,185 million principal amount of debt outstanding and $471 million of available borrowing capacity on the $1 billion 
revolving credit facility that expires in 2021. The revolving credit facility is comprised of a $450 million senior secured revolving 
facility available in U.S. dollars, a $400 million senior secured revolving facility available in U.S. dollars, Euros, Swiss Francs and 
other foreign currencies and a $150 million senior secured revolving facility available in U.S. dollars and Yen. The term A loans and 
revolving credit facility mature in October 2021, while the term B loans mature in 2024 and 2025. Under certain circumstances, the 
maturity date of the term A loans and the senior secured revolving facility may be accelerated to 2020. We are required to make 
scheduled quarterly payments on the term A loans equal to 1.25% of the original principal amount, with the remaining balance paid at 
maturity. We are required to make scheduled quarterly payments on the term B loans equal to approximately 0.25% of the original 
principal amount, with the remaining balance paid at maturity. In addition, beginning with fiscal year ending December 31, 2017, we 
are required to apply 50% of excess cash flow (as defined in our senior secured credit facility), subject to a reduction to 25% or 0% 
depending upon our senior secured first lien net leverage ratio, for prepayment of the Term Loans, with any such prepayment to be 
applied toward principal payments due in subsequent quarters. We are also required to pay an annual commitment fee that ranges from 
0.30% to 0.40% in respect of any unused commitments under the revolving credit facility. The senior secured credit facility is 
collateralized by substantially all of our assets and the assets of our material domestic subsidiaries including 100% of the equity 
interests of substantially all of our material domestic subsidiaries and 66% of the equity interests of substantially all of our first-tier 
material foreign subsidiaries and their domestic subsidiaries.

During the third quarter of 2017, we issued €420 million (approximately $501 million) of senior notes due 2025. The senior 

notes mature on September 15, 2025 and bear an interest rate of 2.875%, which is paid semi-annually on March 15 and September 15, 
beginning on March 15, 2018. Also during the third quarter of 2017, we entered into an amendment to provide for an incremental term 
B loan of $750 million and an increase in restricted payment capacity. The term B loan will mature in 2025 and bears a floating 
interest rate of LIBOR plus 2.00% per year. The net proceeds from the senior notes due 2025 and the incremental term B loan were 
used for the redemption of the outstanding 4.125% Euro denominated senior notes due 2023, to pay down the revolving credit facility, 
to pay certain fees and expenses and for other general corporate purposes, including the repurchase of the Company’s common stock 
and acquisitions.

During the first quarter of 2017, we issued €1.425 billion (approximately $1,522 million) of senior notes due 2025.  The senior 
notes mature on March 15, 2025 and bear an annual interest rate of 3.25%, which is paid semi-annually on March 15 and September 
15, beginning on September 15, 2017. Also during the first quarter of 2017, we refinanced our term B loans in which the maturity was 
extended to 2024 and the interest rate margin on the loan denominated in U.S. dollars was reduced from 2.50% to 2.00% and the 
interest rate margin on the loan denominated in Euros was reduced from 2.75% to 2.00%. See Note 11 to our audited consolidated 
financial statements included elsewhere in this Annual Report on Form 10-K for additional details regarding our credit arrangements.

2016 Financing Transactions

On October 3, 2016, we refinanced the term A loans due 2019 (approximately $884 million) assumed in the Merger with a 
term A loan facility due in 2021 for an aggregate principal amount of approximately $1,350 million comprised of both U.S. dollar 
denominated term A loans and Euro denominated term A loans. Additionally, the revolving credit facility was refinanced to an 
aggregate principal amount equal to $1,000 million. The additional proceeds were used, in part, to fund the redemption on 
November 1, 2016 of $500 million of 6% Senior Notes due 2020 assumed in the Merger, at a redemption price equal to 101.5% of the 
aggregate outstanding principal amount plus accrued interest to the redemption date. We incurred a loss on extinguishment of debt of 
approximately $8 million related to the aggregate payments for make-whole premiums.

59

On September 28, 2016, IMS Health issued $1,750 million of senior unsecured notes, which consisted of (i) $1,050 million of 

5% senior notes due October 2026 (the “5% Dollar Notes”) and (ii) €625 million of 3.5% senior notes due October 2024 (the “3.5% 
Euro Notes” and, together with the 5% Dollar Notes, the “2016 Notes”). The proceeds of the 2016 Notes, which we assumed upon 
closing of the Merger, were used on October 3, 2016 to repay in full ($1,389 million) the term loans outstanding under the Quintiles 
Transnational senior secured credit facilities. Interest on the 2016 Notes is payable semi-annually, beginning on April 15, 2017. The 
notes are guaranteed on a senior unsecured basis by our wholly-owned domestic restricted subsidiaries (excluding IMS Japan K.K.) 
and, subject to certain exceptions, each of our future domestic subsidiaries that guarantees our other indebtedness or indebtedness of 
any of the guarantors. The 5% Dollar Notes and the 3.5% Euro Notes may be redeemed, either together or separately, prior to their 
final stated maturity, subject to a customary make-whole premium, at any time prior to October 15, 2021 with respect to the 5% Dollar 
Notes and October 15, 2019 with respect to the 3.5% Euro Notes (in each case subject to a customary “equity claw” redemption right) 
and thereafter subject to annually declining redemption premiums at any time prior to October 15, 2024 with respect to the 5% Dollar 
Notes and October 15, 2021 with respect to the 3.5% Euro Notes.

We also assumed in the Merger €275 million of 4.125% Senior Notes due in April 2023 (the “4.125% Senior Notes”). As 
noted above, during the third quarter of 2017, the 4.125% Senior Notes were redeemed. Interest on the 4.125% Senior Notes was 
payable semi-annually each year and commenced on October 1, 2015. 

Receivables Financing Facility 

On December 5, 2014, we entered into a four-year arrangement to securitize certain of our accounts receivable. Under the 

receivables financing facility, certain of our accounts receivable are sold on a non-recourse basis by certain of our consolidated 
subsidiaries to another of our consolidated subsidiaries, a bankruptcy-remote special purpose entity (“SPE”). The SPE obtained a term 
loan and revolving loan commitment from a third-party lender, secured by liens on the assets of the SPE, to finance the purchase of 
the accounts receivable, which includes a $275 million term loan and a $25 million revolving loan commitment. The revolving loan 
commitment may be increased by an additional $35 million as amounts are repaid under the term loan. IQVIA has guaranteed the 
performance of the obligations of existing and future subsidiaries that sell and service the accounts receivable under the receivables 
financing facility. The assets of the SPE are not available to satisfy any of our obligations or any obligations of our subsidiaries. As of 
December 31, 2017, the full $25 million of revolving loan commitment was available under the receivables financing facility. On 
December 15, 2017, the Company amended its receivables financing facility to extend the original term of the facility to December 
15, 2020. In addition, the applicable margin (over LIBOR) changed to 90 bps regardless of our credit rating. Prior to the amendment, 
the margin was based on our credit rating and could range from 85 bps to 135 bps.

Restrictive Covenants 

Our debt agreements provide for certain covenants and events of default customary for similar instruments, including a 

covenant not to exceed a specified ratio of consolidated senior secured net indebtedness to Consolidated EBITDA, as defined in the 
senior secured credit facility and a covenant to maintain a specified minimum interest coverage ratio. If an event of default occurs 
under any of the Company’s or the Company’s subsidiaries’ financing arrangements, the creditors under such financing arrangements 
will be entitled to take various actions, including the acceleration of amounts due under such arrangements, and in the case of the 
lenders under the revolving credit facility and New Term Loans, other actions permitted to be taken by a secured creditor. Our long-
term debt arrangements contain usual and customary restrictive covenants that, among other things, place limitations on our ability to 
declare dividends. For additional information regarding these restrictive covenants, see Part II, Item 5 “Market for Registrant’s 
Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities—Dividend Policy” and Note 11 to our 
audited consolidated financial statements included elsewhere in this Annual Report on Form 10-K. At December 31, 2017, the 
Company was in compliance in all material respects with the financial covenants under the Company’s financing arrangements. 

60

Years ended December 31, 2017, 2016 and 2015 

Cash Flow from Operating Activities 

(in millions)
Net cash provided by operating activities

2017 compared to 2016

2017

Year Ended December 31,
2016

2015

  $

970    $

860    $

476  

Cash provided by operating activities increased $110 million in 2017 as compared to 2016. Cash flows from operating 

activities reflects higher cash-related net income of $614 million, offset by higher payments for interest, income taxes and normal 
fluctuations in cash collections from clients and accounts payable. Cash collections from clients can vary significantly each year 
depending on the timing of cash receipts under contractual payment terms relative to the recognition of revenue over a project 
lifecycle and the timing of renewals.

2016 compared to 2015 

Cash provided by operating activities increased $384 million in 2016 as compared to 2015. Cash flows from operating 
activities reflects higher cash-related net income, lower payments for income taxes and normal fluctuations in cash collections from 
clients and accounts payable.   

Cash Flow from Investing Activities

(in millions)
Net cash (used in) provided by investing activities

2017 compared to 2016 

2017

Year Ended December 31,
2016

2015

  $

(1,190)   $

1,731    $

(67)

During 2017, we had net cash outflows from investing activities, while during 2016, we had net cash inflows. The decrease of 
$2,921 million in our net cash flows from investing activities was primarily due to cash from the acquisition of businesses, including 
the Merger in 2016 ($1,887 million), cash used for the acquisition of businesses in 2017 ($854 million) and higher cash used for the 
acquisition of property, equipment and software in 2017 ($205 million).

2016 compared to 2015 

Cash provided by investing activities increased $1,798 million in 2016 as compared 2015. This increase was primarily related 

to cash from the acquisition of businesses, including the Merger ($1,887 million) partially offset by higher cash used for the 
acquisition of property, equipment and software ($86 million). 

61

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Cash Flow from Financing Activities 

(in millions)
Net cash used in financing activities

2017 compared to 2016 

2017

Year Ended December 31,
2016

2015

  $

(72)   $

(2,284)   $

(249)

Cash used in financing activities decreased $2,212 million in 2017 as compared to 2016. The decrease in cash used in 

financing activities was primarily related to higher net borrowings under our credit facilities ($3,781 million), partially offset by 
higher cash used to repurchase common stock ($1,523 million).

2016 compared to 2015 

Cash used in financing activities increased $2,035 million in 2016 as compared to 2015. The increase in cash used in financing 

activities was primarily related to lower net borrowing under our credit facilities ($1,488 million) and higher cash used to repurchase 
common stock ($582 million). 

Contingencies 

We are exposed to certain known contingencies that are material to our investors. The facts and circumstances surrounding 

these contingencies and a discussion of their effect on us are in Note 13 to our audited consolidated financial statements included 
elsewhere in this Annual Report on Form 10-K. These contingencies may have a material effect on our liquidity, capital resources or 
results of operations. In addition, even where our reserves are adequate, the incurrence of any of these liabilities may have a material 
effect on our liquidity and the amount of cash available to us for other purposes. 

We believe that we have made appropriate arrangements in respect of the future effect on us of these known contingencies. We 

also believe that the amount of cash available to us from our operations, together with cash from financing, will be sufficient for us to 
pay any known contingencies as they become due without materially affecting our ability to conduct our operations and invest in the 
growth of our business. 

Contractual Obligations and Commitments 

Below is a summary of our future payment commitments by year under contractual obligations as of December 31, 2017 (in 

millions): 

Long-term debt, including interest(1)
Operating leases
Data acquisition and telecommunication services
Purchase obligations(2)
Commitments to unconsolidated affiliates(3)
Benefit obligations(4)
Uncertain income tax positions(5)
Total

2018

  2019 - 2020  

  2021 - 2022  

  Thereafter  

Total

496    $
169     
254     
28     
—     
22     
9     
978    $

1,251    $
250     
397     
29     
—     
23     
—     
1,950    $

2,336    $
169     
194     
17     
—     
24     
—     
2,740    $

8,429    $
157     
13     
3     
—     
74     
—     
8,676    $

12,512 
745 
858 
77 
— 
143 
9 
14,344  

  $

  $

(1)  Interest payments on our debt are based on the interest rates in effect on December 31, 2017. 
(2)   Purchase obligations are defined as agreements to purchase goods or services that are enforceable and legally binding and that specify all significant terms, 
including fixed or minimum quantities to be purchased, fixed, minimum or variable pricing provisions and the approximate timing of the transactions. 
(3)  We are currently committed to invest $70 million in private equity funds. As of December 31, 2017, we have funded approximately $54 million of these 

commitments and we have approximately $16 million remaining to be funded which has not been included in the above table as we are unable to predict when these 
commitments will be paid. 

(4)  Amounts represent expected future benefit payments for our pension and postretirement benefit plans, as well as expected contributions for 2018 for our funded 
pension benefit plans. We made cash contributions totaling approximately $25 million to our defined benefit plans in 2017, and we estimate that we will make 
contributions totaling approximately $22 million to our defined benefit plans in 2018. Due to the potential impact of future plan investment performance, changes in 
interest rates, changes in other economic and demographic assumptions and changes in legislation in foreign jurisdictions, we are not able to reasonably estimate the 
timing and amount of contributions that may be required to fund our defined benefit plans for periods beyond 2018. 

(5)  As of December 31, 2017, our liability related to uncertain income tax positions was approximately $95 million, $86 million of which has not been included in the 

above table as we are unable to predict when these liabilities will be paid due to the uncertainties in the timing of the settlement of the income tax positions.

62

 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
Application of Critical Accounting Policies 

Note 1 to the audited consolidated financial statements provided elsewhere in this Annual Report on Form 10-K describes the 

significant accounting policies used in the preparation of the consolidated financial statements. The preparation of our consolidated 
financial statements requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, 
and the disclosure of contingent assets and liabilities at the date of the financial statements, as well as the reported amounts of 
revenues and expenses during the period. Our estimates are based on historical experience and various other assumptions we believe 
are reasonable under the circumstances. We evaluate our estimates on an ongoing basis and make changes to the estimates and related 
disclosures as experience develops or new information becomes known. Actual results may differ from those estimates. 

We believe the following critical accounting policies affect our more significant judgments and estimates used in the 

preparation of our consolidated financial statements. 

Revenue Recognition 

We recognize revenue when all of the following conditions are satisfied: (1) there is persuasive evidence of an arrangement, 
(2) the service offering has been delivered to the client, (3) the collection of fees is probable and (4) the arrangement consideration is 
fixed or determinable. We do not recognize revenue with respect to start-up activities including contract and scope negotiation, 
feasibility analysis and conflict of interest review associated with contracts. The costs for these activities are expensed as incurred. For 
contracts in which portions of revenue are contingent upon the occurrence of uncertain future events we recognize the revenue only 
after it has been earned and the contingency has been resolved. 

In some cases, contracts provide for consideration that is contingent upon the occurrence of uncertain future events. We 

recognize contingent revenue when the contingency has been resolved and all other criteria for revenue recognition have been met. 
Cash payments made to clients as incentives to induce the clients to enter into service agreements with us are amortized as a reduction 
of revenue over the period the services are performed. We record revenues net of any tax assessments by governmental authorities, 
such as value added taxes, that are imposed on and concurrent with specific revenue generating transactions. We do not recognize 
revenue with respect to start-up activities including contract and scope negotiation, feasibility analysis and conflict of interest review 
associated with contracts. The costs for these activities are expensed as incurred.

For arrangements that include multiple elements, arrangement consideration is allocated to units of accounting based on the 

relative selling price. The best evidence of selling price of a unit of accounting is vendor-specific objective evidence (“VSOE”), which 
is the price we charge when the deliverable is sold separately. When VSOE is not available to determine selling price, we use relevant 
third-party evidence (“TPE”) of selling price, if available. When neither VSOE nor TPE of selling price exists, we use our best 
estimate of selling price considering all relevant information that is available without undue cost and effort. 

We derive the majority of our revenues in the Commercial Solutions segment from various information and technology service 

offerings. Our revenue arrangements may include multiple elements. A typical information offerings arrangement (primarily under 
fixed-price contracts) may include an ongoing subscription-based deliverable for which revenue is recognized ratably as earned over 
the contract period and/or a one-time delivery of data offerings for which revenue is recognized upon delivery, assuming all other 
criteria are met. Our subscription arrangements typically have terms ranging from one to three years and are generally non-cancelable 
and do not contain refund-type provisions. We also offer technology services offerings that enable our clients to make informed 
business decisions. Technology services offerings consist of a mix of small and large-scale services and consulting projects, multi-
year outsourcing contracts and SaaS licenses. These arrangements typically have terms ranging from several weeks to three years, 
with a majority having terms of one year or less. Revenues for services engagements where deliverables occur ratably over time are 
recognized on a straight-line basis over the term of the arrangement. Revenues from time and material contracts are recognized as the 
services are provided. Revenues from fixed price ad hoc services and consulting contracts are recognized either over the contract term 
based on the ratio of the number of hours incurred for services provided during the period compared to the total estimated hours to be 
incurred over the entire arrangement (efforts based), or upon delivery (completed contract). 

63

The majority of revenue in our Research & Development Solutions segment and Integrated Engagement Services segment is 
recognized based on objective contractual criteria and does not require significant estimates or judgments. However, at any point in 
time we are working on thousands of active client projects, which are governed by individual contracts. Most projects are customized 
based on the needs of the client, the type of services being provided, therapeutic indication of the drug, geographic locations and other 
variables. Project specific terms related to pricing, billing terms and the scope and type of services to be provided are generally 
negotiated and contracted on a project-by-project basis. Changes in the scope of work are common, especially under long-term 
contracts, and generally result in a change in contract value. In such situations, we enter into negotiations for a contract amendment to 
reflect the change in scope and the related price. Depending on the complexity of the amendment, the negotiation process can take 
from a few weeks for a simple adjustment to several months for a complex amendment. Management may authorize the project team 
to commence work on activities outside the contract scope while we negotiate and finalize the contract amendment. In these limited 
cases, if we are not able to obtain a contract amendment from the client, our profit margin on the arrangement may be impacted. This 
result occurs because our costs of delivery are expensed as they are incurred, while revenue is not recognized unless the client has 
agreed to the changes in scope and renegotiated pricing terms, the contract value is amended and all other revenue recognition criteria 
are met. Most contracts are terminable upon 30 to 90 days notice by the client. Our risk of material loss in these situations is mitigated 
as these contracts generally require payment to us for expenses to wind down the clinical trial or project, fees earned to date and, in 
some cases, a termination fee or a payment of some portion of the fees or profits that could have been earned under the contract if it 
had not been terminated early. In addition, our contract terms provide for payment terms that generally correspond with performance 
of the services. Termination fees are included in revenues when realization is assured. 

See Note 1 to our audited consolidated financial statements included elsewhere in this Annual Report on Form 10-K for details 

regarding the new revenue recognition standard, which will be effective January 1, 2018. 

Accounts Receivable and Unbilled Services 

Accounts receivable represents amounts billed to clients. Revenues recognized in excess of billings are classified as unbilled 

services. The realization of these amounts is based on the client’s willingness and ability to pay us. We have an allowance for doubtful 
accounts based on management’s estimate of probable losses we expect to incur resulting from a client failing to pay us. Our 
allowance for doubtful accounts, and losses from clients failing to pay us, have not been material to our results of operations. If any of 
these estimates change or actual results differs from expected results, then an adjustment is recorded in the period in which the 
amounts become reasonably estimable. These adjustments could have a material effect on our results of operations. 

Investments in Unconsolidated Affiliates—Equity Method Investments 

We have investments in unconsolidated affiliates that are accounted for under the equity method of accounting. Periodically, 
we review our investments for a decline in value which we believe may be other than temporary. Should we identify such a decline, 
we will record a loss through earnings to establish a new cost basis for the investment. These losses could have a material adverse 
effect on our results of operations. 

Income Taxes 

Certain items of income and expense are not recognized on our income tax returns and financial statements in the same year, 

which creates timing differences. The income tax effect of these timing differences results in (1) deferred income tax assets that create 
a reduction in future income taxes and (2) deferred income tax liabilities that create an increase in future income taxes. Recognition of 
deferred income tax assets is based on management’s belief that it is more likely than not that the income tax benefit associated with 
certain temporary differences, income tax operating loss and capital loss carryforwards and income tax credits, would be realized. We 
recorded a valuation allowance to reduce our deferred income tax assets for those deferred income tax items for which it was more 
likely than not that realization would not occur. We determined the amount of the valuation allowance based, in part, on our 
assessment of future taxable income and in light of our ongoing income tax strategies. If our estimate of future taxable income or tax 
strategies changes at any time in the future, we would record an adjustment to our valuation allowance. Recording such an adjustment 
could have a material effect on our financial condition or results of operations. 

64

Income tax expense is based on the distribution of profit before income tax among the various taxing jurisdictions in which we 

operate, adjusted as required by the income tax laws of each taxing jurisdiction. Changes in the distribution of profits and losses 
among taxing jurisdictions may have a significant impact on our effective income tax rate. We do not consider the undistributed 
earnings of our foreign subsidiaries to be indefinitely reinvested outside of the United States. Accordingly, we have provided a 
deferred income tax liability related to those undistributed earnings. The associated foreign income taxes on our foreign earnings 
could be available as a credit in the United States on our income taxes. We recognize foreign tax credits to the extent that the 
recognition is supported by projected foreign source income. See Note 18 to our audited consolidated financial statements included 
elsewhere in the Annual Report on Form 10-K for details regarding the Tax Cuts and Jobs Act and the impact on our consolidated 
financial statements.

Business Combinations 

We use the acquisition method to account for business combinations, and accordingly, the identifiable assets acquired, the 

liabilities assumed and any non-controlling interest in the acquiree are recorded at their estimated fair values on the date of the 
acquisition. We use significant judgments, estimates and assumptions in determining the estimated fair value of assets acquired, 
liabilities assumed and non-controlling interest including expected future cash flows, discount rates that reflect the risk associated with 
the expected future cash flows and estimated useful lives. 

When a business combination involves contingent consideration, we recognize a liability equal to the estimated fair value of 
the contingent consideration obligation at the date of the acquisition. The estimate of fair value of a contingent consideration liability 
requires subjective assumptions to be made regarding future business results including revenues and net new business, discount rates 
that reflect the risk associated with the expected future cash flows and probabilities assigned to various potential business result 
scenarios. We reassess the estimated fair value of the contingent consideration each financial reporting period over the term of the 
arrangement. Any resulting changes are recognized in earnings and could have a material effect on our results of operations. 

Goodwill, Tangible and Identifiable Intangible Assets 

We have recorded and allocated to our reporting units the excess of the cost over the fair value of the net assets acquired, 
known as goodwill. The recoverability of the goodwill and indefinite-lived intangible assets are evaluated annually for impairment, or 
if and when events or circumstances indicate a possible impairment. We review the carrying values of other identifiable intangible 
assets if the facts and circumstances indicate a possible impairment. Goodwill and indefinite-lived intangible assets are not amortized, 
and other identifiable intangible assets are amortized over their estimated useful lives. We believe that the risk of an impairment to 
goodwill or indefinite-lived intangible assets is currently very low. 

For goodwill, we perform a qualitative analysis to determine whether it is more likely than not that the estimated fair value of a 

reporting unit is less than its book value. This includes a qualitative analysis of macroeconomic conditions, industry and market 
considerations, internal cost factors, financial performance, fair value history and other company specific events. If this qualitative 
analysis indicates that it is more likely than not that estimated fair value is less than the book value for the respective reporting unit, 
we apply a two-step impairment test in which we determine whether the estimated fair value of the reporting unit is in excess of its 
carrying value. If the carrying value of the net assets assigned to the reporting unit exceeds the estimated fair value of the reporting 
unit, we perform the second step of the impairment test to determine the implied estimated fair value of the reporting unit’s goodwill. 
We determine the implied estimated fair value of goodwill by determining the present value of the estimated future cash flows for 
each reporting unit and comparing the reporting unit’s risk profile and growth prospects to selected, reasonably similar publicly traded 
companies. The inherent subjectivity of applying a discounted cash flow and market comparables approach to valuing our assets and 
liabilities could have a significant impact on our analysis. Any future impairment could have a material adverse effect on our financial 
condition or results of operations. 

For indefinite-lived intangible assets, we perform a qualitative analysis to determine whether it is more likely than not that the 
estimated fair value of the indefinite-lived intangible asset is less than its carrying value. If this qualitative analysis indicates that it is 
more likely than not that the estimated fair value is less than the carrying value of the indefinite-lived intangible asset, we determine 
the estimated fair value of the indefinite-lived intangible asset (trade name) by determining the present value of the estimated royalty 
payments on an after-tax basis that it would be required to pay the owner for the right to use such trade name. If the carrying amount 
exceeds the estimated fair value, an impairment loss is recognized in an amount equal to the excess. Any future impairment could 
have a material adverse effect on our financial condition or results of operations. 

65

We review the carrying values of property and equipment if the facts and circumstances suggest that a potential impairment 
may have occurred. If this review indicates that carrying values will not be recoverable, as determined based on undiscounted cash 
flows over the remaining depreciation or amortization period, we will reduce carrying values to estimated fair value. The inherent 
subjectivity of our estimates of future cash flows could have a significant impact on our analysis. Any future write-offs of long-lived 
assets could have a material adverse effect on our financial condition or results of operations. 

Stock-based Compensation 

We measure compensation cost for stock-based payment awards (stock options and stock appreciation rights) granted to 
employees and non-employee directors at fair value using the Black-Scholes-Merton option-pricing model and for performance 
awards using the Monte Carlo simulation model. Stock-based compensation expense includes stock-based awards granted to 
employees and non-employee directors and has been reported in selling, general and administrative expenses in our consolidated 
statements of income based upon the classification of the individuals who were granted stock-based awards. 

The Black-Scholes-Merton option-pricing model requires the use of subjective assumptions, including share price volatility, 

the expected life of the award, risk-free interest rate and the fair value of the underlying common shares on the date of grant. In 
developing our assumptions, we take into account the following: 

•

• 

• 

• 

• 

We calculate expected volatility based on reported data for selected reasonably similar publicly traded companies for 
which the historical information is available. We plan to continue to use the guideline peer group volatility information 
until the historical volatility of our common shares is relevant to measure expected volatility for future award grants; 

We determine the risk-free interest rate by reference to implied yields available from United States Treasury securities 
with a remaining term equal to the expected life assumed at the date of grant; 

We estimate the dividend yield to be zero as we do not currently anticipate paying any future dividends; 

We estimate the average expected life of the award based on our historical experience; and 

We estimate forfeitures based on our historical analysis of actual forfeitures. 

Pensions and Other Postretirement Benefits

We provide retirement benefits to certain employees, including defined benefit pension plans and postretirement medical 

plans. The determination of benefit obligations and expense is based on actuarial models. In order to measure benefit costs and 
obligations using these models, critical assumptions are made with regard to the discount rate, expected return on plan assets, cash 
balance crediting rate, lump sum conversion rate and the assumed rate of compensation increases. In addition, retiree medical care cost 
trend rates are a key assumption used exclusively in determining costs for our postretirement health care and life insurance benefit 
plans. Management reviews these critical assumptions at least annually. Other assumptions involve demographic factors such as 
turnover, retirement and mortality rates. Management reviews these assumptions periodically and updates them when its experience 
deems it appropriate to do so. 

The discount rate is the rate at which the benefit obligations could be effectively settled and is determined annually by 

management. For United States plans, the discount rate is based on results of a modeling process in which the plans’ expected cash 
flow (determined on a projected benefit obligation basis) is matched with spot rates developed from a yield curve comprised of high-
grade (Moody’s Aa and above, or Standard and Poor’s AA and above) non-callable corporate bonds to develop the present value of 
the expected cash flow, and then determining the single rate (discount rate), which when applied to the expected cash flow derives that 
same present value. In the United Kingdom specifically, the discount rate is set based on the yields on a universe of high quality non-
callable corporate bonds denominated in the British Pound, appropriate to the duration of plan liabilities. For the other non-United 
States plans, the discount rate is based on the current yield of an index of high quality corporate bonds. As a sensitivity measure, a 25 
basis point increase in the discount rate for our United States plan and United Kingdom plans, absent any offsetting changes in other 
assumptions, would result in a $1 million decrease and a less than $1 million increase, respectively, in pension expense at December 
31, 2017.  

Under the United States qualified retirement plan, participants have a notional retirement account that increases with pay and 

investment credits. The rate used to determine the investment credit (cash balance crediting rate) varies monthly. At retirement, the 
account is converted to a monthly retirement benefit. 

66

In selecting an expected return on plan asset assumption, we consider the returns being earned by each plan investment 

category in the fund, the rates of return expected to be available for reinvestment and long-term economic forecasts for the type of 
investments held by the plan. The actual return on plan assets will vary from year to year versus this assumption. We believe it is 
appropriate to use long-term expected forecasts in selecting the expected return on plan assets. As such, there can be no assurance that 
our actual return on plan assets will approximate the long-term expected forecasts. As a sensitivity measure, a 25 basis point change in 
the expected return on assets (“EROA”) assumption for our United States plan, absent any offsetting changes in other assumptions, 
would result in a less than $1 million increase or decrease in pension expense at December 31, 2017. For our United Kingdom plans, a 
25 basis point change in the EROA assumption, absent any offsetting changes in other assumptions, would result in a less than $1 
million increase or decrease in pension expense at December 31, 2017. While we believe that the assumptions used are reasonable, 
differences in actual experience or changes in assumptions may materially affect our pension and postretirement obligations and future 
expense. 

We utilize a corridor approach to amortizing unrecognized gains and losses in the pension and postretirement plans. 
Amortization occurs when the accumulated unrecognized net gain or loss balance exceeds the criterion of 10% of the larger of the 
beginning balances of the projected benefit obligation or the market-related value of the plan assets. The excess unrecognized gain or 
loss balance is then amortized using the straight-line method over the average remaining service life of active employees expected to 
receive benefits. At December 31, 2017, the weighted-average remaining service life of active employees was approximately 12 years. 

Foreign Currency 

We have significant investments in non-United States countries. Therefore, changes in the value of foreign currencies affect 

our consolidated financial statements when translated into United States dollars. For all operations outside the United States where we 
have designated the local currency as the functional currency, assets and liabilities are translated using end-of-period exchange rates; 
revenues, expenses and cash flows are translated using average rates of exchange prevailing during the period the transactions 
occurred. Translation gains and losses are included as an adjustment to the accumulated other comprehensive income (loss) 
component of stockholders’ equity. In addition, gains and losses from foreign currency transactions, such as those resulting from the 
settlement and revaluation of third-party and intercompany foreign receivables and payables, are included in the determination of net 
income (loss). 

For operations outside the United States that are considered to be highly inflationary or where the United States dollar is 
designated as the functional currency, monetary assets and liabilities are remeasured using end-of-period exchange rates, whereas non-
monetary accounts are remeasured using historical exchange rates, and all remeasurement and transaction adjustments are recognized 
in other expense (income), net.  

Recently Issued Accounting Standards 

Information relating to recently issued accounting standards is included in Note 1 to our audited consolidated financial 

statements included elsewhere in this Annual Report on Form 10-K. 

67

Item 7A. Quantitative and Qualitative Disclosures About Market Risk 

Market risk is the potential loss arising from adverse changes in market rates and prices. In the ordinary course of business, we 

are exposed to various market risks and we regularly evaluate our exposure to such changes. Our overall risk management strategy 
seeks to balance the magnitude of the exposure and the cost and availability of appropriate financial instruments. The following 
analyses present the sensitivity of our financial instruments to hypothetical changes that are reasonably possible over a one-year 
period. 

Foreign Currency Exchange Rates 

We transact business in more than 100 countries and approximately 55 currencies and are subject to risks associated with 

fluctuating foreign currency exchange rates. Our objective is to reduce earnings and cash flow volatility associated with foreign 
currency exchange rate movements. Accordingly, we enter into foreign currency forward contracts to minimize the impact of foreign 
exchange movements on non–functional currency assets and liabilities. We also enter into foreign currency forward contracts to hedge 
certain forecasted foreign currency cash flows related to service contracts and to hedge non-United States dollar anticipated 
intercompany royalties. It is our policy to enter into foreign currency transactions only to the extent necessary to meet our objectives 
as stated above. We do not enter into foreign currency transactions for investment or speculative purposes. The principal currencies 
hedged are the Euro, the British Pound, the Japanese Yen, the Swiss Franc and the Canadian dollar. 

The contractual value of our foreign exchange derivative instruments, all of which were foreign exchange forward contracts, 
was approximately $282 million at December 31, 2017. The fair value of these contracts is subject to change as a result of potential 
changes in foreign exchange rates. We assess our market risk based on changes in foreign exchange rates utilizing a sensitivity 
analysis. The sensitivity analysis measures the potential loss in fair values based on a hypothetical 10% change in foreign currency 
exchange rates. The potential loss in fair value for foreign exchange forward contracts based on a hypothetical 10% decrease in the 
value of the United States dollar or, in the case of non-United States dollar related contracts, the currency being purchased, was $12 
million at December 31, 2017. However, the change in the fair value of the foreign exchange forward contracts would likely be offset 
by a change in the value of the future service contract revenue, royalty or balance sheet exposure being hedged caused by the currency 
exchange rate fluctuation. The estimated fair values of the foreign exchange forward contracts were determined based on quoted 
market prices. 

Exchange rate fluctuations affect the United States dollar value of foreign currency revenue and expenses and may have a 

significant effect on our results. Excluding the impacts from any outstanding or future hedging transactions, a hypothetical 10% 
change in average exchange rates used to translate all foreign currencies to the United States dollar would have impacted income 
before income taxes for 2017 by approximately $112 million. The actual impact of exchange rate movements in the future could differ 
materially from this hypothetical analysis, based on the mix of foreign currencies and the timing and magnitude of individual 
exchange rate movements. 

Additionally, commencing in 2016, we designated a portion of our foreign currency denominated debt as a hedge of our net 
investment in foreign subsidiaries to reduce the volatility in stockholders’ equity caused by changes in the Euro exchange rate with 
respect to the United States dollar. As of December 31, 2017, these borrowings (net of original issue discount) were €4,036 million 
($4,835 million). A hypothetical 10% decrease in the value of the United States dollar would lead to a potential loss in fair value of 
$484 million. However, this change in fair value would be offset by the change in value of the hedged portion of our net investment in 
foreign subsidiaries caused by the currency exchange rate fluctuation.  

Interest Rates 

Because we have variable rate debt, fluctuations in interest rates affect our business. We attempt to minimize interest rate risk 

and lower our overall borrowing costs through the utilization of derivative financial instruments, primarily interest rate caps and 
swaps. We have entered into interest rate caps and swaps with financial institutions that have reset dates and critical terms that match 
the underlying debt. Accordingly, any change in market value associated with the interest rate caps and swaps is offset by the opposite 
market impact on the related debt. As of December 31, 2017, we had approximately $5.5 billion of variable rate indebtedness and 
interest rate caps and swaps with a notional value of $1.6 billion. Because we do not attempt to hedge all of our variable rate debt, we 
may incur higher interest costs for the portion of our variable rate debt that is not hedged. Excluding debt covered by hedges, each 
quarter-point increase or decrease in the interest rate on our variable rate debt would result in our interest expense changing by 
approximately $10 million per year. 

68

Marketable Securities 

At December 31, 2017, we held investments in marketable equity securities. These investments are classified as either trading 
securities or available-for-sale securities and are recorded at fair value. These securities are subject to price risk. As of December 31, 
2017, the fair value of these investments was $46 million based on the quoted market value of the securities. The potential loss in fair 
value resulting from a hypothetical decrease of 10% in quoted market values was approximately $5 million at December 31, 2017. 

69

Item 8. Financial Statements and Supplementary Data 

MANAGEMENT’S REPORT ON INTERNAL CONTROL OVER FINANCIAL REPORTING 

The management of IQVIA Holdings Inc. (the “Company”) is responsible for establishing and maintaining adequate internal 

control over financial reporting. Internal control over financial reporting is a process designed to provide reasonable assurance 
regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with 
generally accepted accounting principles. A company’s internal control over financial reporting includes those policies and procedures 
that pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the 
assets of the company; provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial 
statements in accordance with generally accepted accounting principles, and that receipts and expenditures of the company are being 
made only in accordance with authorizations of management and directors of the company; and provide reasonable assurance 
regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company’s assets that could have a 
material effect on the financial statements. 

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, 

projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of 
changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate. 

Management assessed the effectiveness of the Company’s internal control over financial reporting as of December 31, 2017. In 
making this assessment, management used the framework established in Internal Control—Integrated Framework (2013) issued by the 
Committee of Sponsoring Organizations of the Treadway Commission (COSO). As a result of this assessment and based on the 
criteria in the COSO framework, management has concluded that, as of December 31, 2017, the Company’s internal control over 
financial reporting was effective. 

The effectiveness of the Company’s internal control over financial reporting as of December 31, 2017 has been audited by 

PricewaterhouseCoopers LLP, an independent registered public accounting firm, as stated in their report which appears herein. 

/s/ Ari Bousbib
Ari Bousbib
Chairman, Chief Executive Officer and President
(Principal Executive Officer)

February 16, 2018 

/s/ Michael R. McDonnell
Michael R. McDonnell
Executive Vice President and Chief Financial Officer
(Principal Financial Officer)

70

 
 
 
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Board of Directors and Stockholders of IQVIA Holdings Inc.

 Opinions on the Financial Statements and Internal Control over Financial Reporting

We have audited the accompanying consolidated balance sheets of IQVIA Holdings Inc. and its subsidiaries as of December 
31, 2017 and 2016, and the related consolidated statements of income, comprehensive income, cash flows and stockholders’ equity 
(deficit) for each of the three years in the period ended December 31, 2017, including the related notes and financial statement 
schedules listed in the index appearing under Item 15(a)(2) (collectively referred to as the “consolidated financial statements”). We 
also have audited the Company’s internal control over financial reporting as of December 31, 2017, based on criteria established in 
Internal Control - Integrated Framework (2013) issued by the Committee of Sponsoring Organizations of the Treadway Commission 
(COSO).  

In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial 

position of the Company as of December 31, 2017 and 2016, and the results of its operations and its cash flows for each of the three 
years in the period ended December 31, 2017 in conformity with accounting principles generally accepted in the United States of 
America. Also in our opinion, the Company maintained, in all material respects, effective internal control over financial reporting as 
of December 31, 2017, based on criteria established in Internal Control - Integrated Framework (2013) issued by the COSO.

Basis for Opinions

The Company’s management is responsible for these consolidated financial statements, for maintaining effective internal 

control over financial reporting, and for its assessment of the effectiveness of internal control over financial reporting, included in the 
accompanying Management’s Report on Internal Control over Financial Reporting. Our responsibility is to express opinions on the 
Company’s consolidated financial statements and on the Company’s internal control over financial reporting based on our audits. We 
are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (“PCAOB”) and are 
required to be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable rules 
and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform 

the audits to obtain reasonable assurance about whether the consolidated financial statements are free of material misstatement, 
whether due to error or fraud, and whether effective internal control over financial reporting was maintained in all material respects.  

Our audits of the consolidated financial statements included performing procedures to assess the risks of material misstatement 

of the consolidated financial statements, whether due to error or fraud, and performing procedures that respond to those risks. Such 
procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the consolidated financial 
statements. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well 
as evaluating the overall presentation of the consolidated financial statements. Our audit of internal control over financial reporting 
included obtaining an understanding of internal control over financial reporting, assessing the risk that a material weakness exists, and 
testing and evaluating the design and operating effectiveness of internal control based on the assessed risk. Our audits also included 
performing such other procedures as we considered necessary in the circumstances. We believe that our audits provide a reasonable 
basis for our opinions.

71

Definition and Limitations of Internal Control over Financial Reporting

A company’s internal control over financial reporting is a process designed to provide reasonable assurance regarding the 

reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally 
accepted accounting principles. A company’s internal control over financial reporting includes those policies and procedures that 
(i) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the 
assets of the company; (ii) provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial 
statements in accordance with generally accepted accounting principles, and that receipts and expenditures of the company are being 
made only in accordance with authorizations of management and directors of the company; and (iii) provide reasonable assurance 
regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company’s assets that could have a 
material effect on the financial statements.

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, 

projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of 
changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.

/s/ PricewaterhouseCoopers LLP

Raleigh, North Carolina 
February 16, 2018

We have served as the Company’s auditor since 2002. 

72

 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF INCOME 

(in millions, except per share data)
Revenues
Reimbursed expenses
Total revenues

Costs of revenue, exclusive of depreciation and amortization
Costs of revenue, reimbursed expenses
Selling, general and administrative expenses
Depreciation and amortization
Restructuring costs
Merger related costs
Impairment charges

Income from operations

Interest income
Interest expense
Loss on extinguishment of debt
Other expense (income), net

Income before income taxes and equity in earnings (losses) of
   unconsolidated affiliates
Income tax (benefit) expense

Income before equity in earnings (losses) of unconsolidated affiliates

Equity in earnings (losses) of unconsolidated affiliates

Net income

Net income attributable to non-controlling interests
Net income attributable to IQVIA Holdings Inc.
Earnings per share attributable to common stockholders:

Basic
Diluted

Weighted average common shares outstanding:

Basic
Diluted

  $

  $

  $
  $

2017

Year Ended December 31,
2016

2015

8,060    $
1,679     
9,739     
4,622     
1,679     
1,605     
1,011     
63     
—     
40     
719     
(7)    
346     
19     
30     

331     
(987)    
1,318     
10     
1,328     
(19)    
1,309    $

6.01    $
5.88    $

217.8     
222.6     

5,364    $
1,514     
6,878     
3,236     
1,514     
1,011     
289     
71     
87     
28     
642     
(4)    
144     
31     
(8)    

479     
345     
134     
(4)    
130     
(15)    
115    $

0.77    $
0.76    $

149.1     
152.0     

4,326 
1,411 
5,737 
2,705 
1,411 
815 
128 
30 
— 
2 
646 
(4)
101 
8 
2 

539 
159 
380 
8 
388 
(1)
387 

3.15 
3.08 

123.0 
125.6  

The accompanying notes are an integral part of these consolidated financial statements. 

73

 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
      
      
  
   
      
      
  
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME

(in millions)
Net income
Comprehensive income (loss) adjustments:

2017

Year Ended December 31,
2016

2015

  $

1,328    $

130    $

388 

Unrealized gains (losses) on derivative instruments, net of income tax
   expense (benefit) of $1, $3 and ($4)
Defined benefit plan adjustments, net of income tax expense of
   $3, $11 and $—
Foreign currency translation, net of income tax benefit of
   ($201), ($9) and ($5)
Reclassification adjustments:

(Gains) losses on derivative instruments included in net income, net of
   income tax expense of $—, $7 and $6
Amortization of actuarial losses and prior service costs included in net
   income

Comprehensive income (loss)

Comprehensive (income) loss attributable to non-controlling interests

Comprehensive income (loss) attributable to IQVIA Holdings Inc.

  $

4     

5     

(7)    

23     

614     

(513)    

(1)    

21     

1     
1,951     
(26)    
1,925    $

1     
(345)    
1     
(344)   $

(9)

— 

(60)

12 

1 
332 
3 
335  

The accompanying notes are an integral part of these consolidated financial statements. 

74

 
 
 
 
   
   
 
   
      
      
  
   
   
   
   
      
      
  
   
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
CONSOLIDATED BALANCE SHEETS 

(in millions, except per share data)

Current assets:

ASSETS

Cash and cash equivalents
Trade accounts receivable and unbilled services, net
Prepaid expenses
Income taxes receivable
Investments in debt, equity and other securities
Other current assets and receivables

Total current assets
Property and equipment, net
Investments in debt, equity and other securities
Investments in unconsolidated affiliates
Goodwill
Other identifiable intangibles, net
Deferred income taxes
Deposits and other assets

Total assets

LIABILITIES AND STOCKHOLDERS’ EQUITY

Current liabilities:

Accounts payable
Accrued expenses
Unearned income
Income taxes payable
Current portion of long-term debt
Other current liabilities

Total current liabilities

Long-term debt, less current portion
Deferred income taxes
Other liabilities

Total liabilities

Commitments and contingencies (Note 1)
Stockholders’ equity:

Common stock and additional paid-in capital, 400.0 shares authorized at
   December 31, 2017 and 2016, $0.01 par value, 249.5 and 248.3 shares
   issued at December 31, 2017 and 2016, respectively
Retained earnings (accumulated deficit)
Treasury stock, at cost, 41.4 and 12.9 shares at December 31, 2017 and 2016,
    respectively
Accumulated other comprehensive income (loss)

Equity attributable to IQVIA Holdings Inc.’s stockholders

Non-controlling interests

Total stockholders’ equity
Total liabilities and stockholders’ equity

December 31,

2017

2016

  $

  $

  $

  $

959    $

1,993   
146   
47   
46   
259   
3,450   
440   
8   
70   
11,850   
6,591   
98   
235   
22,742    $

322    $

1,664   
733   
72   
103   
10   
2,904   
10,122   
918   
440   
14,384   

10,782   
655   

(3,374)  
46   
8,109   
249   
8,358   
22,742    $

1,198 
1,707 
123 
34 
40 
235 
3,337 
406 
13 
69 
10,727 
6,390 
89 
177 
21,208 

250 
1,493 
774 
76 
92 
20 
2,705 
7,108 
2,133 
402 
12,348 

10,602 
(399)

(1,000)
(570)
8,633 
227 
8,860 
21,208  

The accompanying notes are an integral part of these consolidated financial statements. 

75

 
 
 
 
   
 
 
 
    
 
  
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF CASH FLOWS 

2017

Year Ended December 31,
2016

2015

  $

1,328    $

130    $

388 

(in millions)
Operating activities:

Net income
Adjustments to reconcile net income to cash provided by operating
   activities:

Depreciation and amortization
Amortization of debt issuance costs and discount
Amortization of accumulated other comprehensive loss on terminated
   interest rate swaps
Stock-based compensation
Impairment of goodwill, identifiable intangible and long-lived assets
Gain on disposals of property and equipment, net
(Earnings) loss from unconsolidated affiliates
(Gain) loss on investments, net
(Benefit from) provision for deferred income taxes
Excess income tax benefits from stock-based award activities

Changes in operating assets and liabilities:

Accounts receivable and unbilled services
Prepaid expenses and other assets
Accounts payable and accrued expenses
Unearned income
Income taxes payable and other liabilities

Net cash provided by operating activities

Investing activities:

Acquisition of property, equipment and software
Net cash (paid for) assumed from acquisition of businesses
Disposition of business, net of cash disposed
Sales (purchases) of trading securities, net
Proceeds from corporate owned life insurance policies
Proceeds from sale of equity securities
Investments in unconsolidated affiliates, net of payments received
Termination of interest rate swaps
Other

Net cash (used in) provided by investing activities

Financing activities:

Proceeds from issuance of debt
Payment of debt issuance costs
Repayment of debt
Proceeds from revolving credit facility
Repayment of revolving credit facility
Principal payments on capital lease obligations
Payment of contingent consideration
Stock issued under employee stock purchase and option plans
Repurchase of common stock
Excess income tax benefits from stock-based award activities

Net cash used in financing activities
Effect of foreign currency exchange rate changes on cash
(Decrease) increase in cash and cash equivalents
Cash and cash equivalents at beginning of period
Cash and cash equivalents at end of period

  $

1,011     
9     

3     
106     
40     
(1)    
(10)    
(8)    
(1,216)    
—     

(142)    
(54)    
90     
(104)    
(82)    
970     

(369)    
(854)    
12     
2     
—     
—     
15     
—     
4     
(1,190)    

5,242     
(50)    
(2,883)    
1,921     
(1,767)    
(2)    
(4)    
91     
(2,620)    
—     
(72)    
53     
(239)    
1,198     
959    $

289     
30     

3     
80     
28     
(1)    
8     
(13)    
135     
(41)    

(62)    
(8)    
160     
52     
70     
860     

(164)    
1,887     
—     
(40)    
21     
41     
(17)    
—     
3     
1,731     

466     
(7)    
(1,949)    
172     
—     
(2)    
(5)    
97     
(1,097)    
41     
(2,284)    
(86)    
221     
977     
1,198    $

128 
9 

8 
38 
2 
(1)
(8)
1 
18 
(39)

(246)
15 
104 
54 
5 
476 

(78)
32 
— 
— 
— 
— 
(12)
(11)
2 
(67)

2,249 
(22)
(2,057)
— 
— 
(4)
(3)
64 
(515)
39 
(249)
(50)
110 
867 
977  

The accompanying notes are an integral part of these consolidated financial statements. 

76

 
 
 
 
 
 
 
 
 
 
   
      
      
  
   
      
      
  
   
   
   
   
   
   
   
   
   
   
   
      
      
  
   
   
   
   
   
   
   
      
      
  
   
   
   
   
   
   
   
   
   
   
   
      
      
  
   
   
   
   
   
   
   
   
   
   
   
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY (DEFICIT)

 (in millions)
Balance, December 31, 2014
Issuance of common stock
Repurchase of common stock
Stock-based compensation
Income tax benefits from stock-based award activities
Q2 Solutions business combination
Non-controlling interest related to Q2 Solutions transaction
Deferred tax impact of the Q2 Solutions transaction
Net income
Unrealized loss on derivative instruments, net of tax
Foreign currency translation, net of tax
Reclassification adjustments, net of tax
Balance, December 31, 2015
Issuance of common stock
Repurchase of common stock before October 3, 2016
Repurchase of common stock on or after October 3, 2016
Stock-based compensation
Income tax benefits from stock-based award activities
Investment by non-controlling interest
Net income
Unrealized gain on derivative instruments, net of tax
Defined benefit plan adjustments, net of tax
Foreign currency translation, net of tax
Reclassification adjustments, net of tax
Balance, December 31, 2016
Issuance of common stock
Repurchase of common stock
Repurchase and retirement of common stock
Stock-based compensation
Distribution to non-controlling interest
Net income
Unrealized gain on derivative instruments, net of tax
Defined benefit plan adjustments, net of tax
Foreign currency translation, net of tax
Balance, December 31, 2017

Common
Stock
Shares

Treasury
Stock
Shares

Common
Stock

Additional
Paid-In
Capital

Retained 
Earnings 
(Accumulated 
Deficit)

Treasury
Stock

Accumulated
Other
Comprehensive
Income (Loss)  

Non-
controlling
Interests

Total

124.1 
3.1 
(7.8)    
— 
— 
— 
— 
— 
— 
— 
— 
— 
119.4 
130.4 

(1.5)    
— 
— 
— 
— 
— 
— 
— 
— 
— 
248.3 
3.7 
— 
(2.5)    
— 
— 
— 
— 
— 
— 
249.5 

— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
(12.9)    
— 
— 
— 
— 
— 
— 
— 
— 
(12.9)    
— 
(28.5)    
— 
— 
— 
— 
— 
— 
— 
(41.4)   $

1 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
1 
1 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
2 
— 
— 
— 
— 
— 
— 
— 
— 
— 
2 

  $

143 
65 
(455)    
31 
39 
423 
(231)    
(7)    
— 
— 
— 
— 
8 
10,522 

(46)    
— 
76 
41 
(1)    
— 
— 
— 
— 
— 
10,600 
— 
— 
— 
180 
— 
— 
— 
— 
— 
10,780 

  $

(788)    
— 
(61)    
— 
— 
— 
— 
— 
387 
— 
— 
— 
(462)    
— 
(52)    
— 
— 
— 
— 
115 
— 
— 
— 
— 
(399)    
— 
— 
(255)    
— 
— 
1,309 
— 
— 
— 
655 

  $

— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
— 
(1,000)    
— 
— 
— 
— 
— 
— 
— 
— 
(1,000)    
— 
(2,374)    
— 
— 
— 
— 
— 
— 
— 
(3,374)   $

(59)    
— 
— 
— 
— 
— 
— 
— 
— 
(9)    
(56)    
13 
(111)    
— 
— 
— 
— 
— 
— 
— 
(7)    
23 
(497)    
22 
(570)    
— 
— 
— 
— 
— 
— 
4 
5 
607 
46 

  $

— 
— 
— 
— 
— 
— 
231 
— 
1 
— 
(4)    
— 
228 
— 
— 
— 
— 
— 
— 
15 
— 
— 
(16)    
— 
227 
— 
— 
— 
— 
(4)    
19 
— 
— 
7 
249 

  $

(703)
65 
(516)
31 
39 
423 
— 
(7)
388 
(9)
(60)
13 
(336)
10,523 
(98)
(1,000)
76 
41 
(1)
130 
(7)
23 
(513)
22 
8,860 
— 
(2,374)
(255)
180 
(4)
1,328 
4 
5 
614 
8,358  

The accompanying notes are an integral part of these consolidated financial statements. 

77

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements 

1. Summary of Significant Accounting Policies 

The Company 

Conducting business in more than 100 countries with over 55,000 employees, IQVIA Holdings Inc. (together with its 

subsidiaries, the “Company” or “IQVIA”) is a leading integrated information and technology-enabled healthcare service provider 
worldwide, dedicated to helping its clients improve their clinical, scientific and commercial results. 

On October 3, 2016, Quintiles Transnational Holdings Inc. (“Quintiles”) completed its previously announced merger of equals 
transaction (the “Merger”) with IMS Health Holdings, Inc. (“IMS Health”). Pursuant to the terms of the merger agreement dated as of 
May 3, 2016 between Quintiles and IMS Health (the “Merger Agreement”), IMS Health was merged with and into Quintiles, and the 
separate corporate existence of IMS Health ceased, with Quintiles continuing as the surviving corporation (the “Surviving 
Corporation”). Immediately prior to the completion of the Merger, Quintiles reincorporated as a Delaware corporation. The Surviving 
Corporation changed its name to Quintiles IMS Holdings, Inc (“QuintilesIMS”). At the effective time of the Merger, each issued and 
outstanding share of IMS Health common stock, par value $0.01 per share (“IMS Health common stock”), was automatically 
converted into 0.3840 of a share of the Company’s common stock, par value $0.01 per share. In addition, immediately following the 
effective time of the Merger, Quintiles Transnational Corp (“Quintiles Corp.”), a direct subsidiary of Quintiles, was merged with and 
into IMS Health Incorporated, following which IMS Health Incorporated will continue as a direct, wholly-owned subsidiary of the 
Surviving Corporation. See Note 15 for additional information regarding the Merger. 

On November 6, 2017, the Company filed a Certificate of Amendment to its Amended and Restated Certificate of 
Incorporation (the “Certificate of Amendment”) to effect a change of the Company’s name from “Quintiles IMS Holdings, Inc.” to 
“IQVIA Holdings Inc.” (the “Name Change”). 

On November 15, 2017, shares of the Company commenced trading under an updated New York Stock Exchange ticker 

symbol, “IQV” (formerly the shares traded under the ticker symbol “Q”). 

Principles of Consolidation 

The accompanying consolidated financial statements include the accounts and operations of the Company, its subsidiaries and 
investments in which the Company has control. Amounts pertaining to the non-controlling ownership interests held by third parties in 
the operating results and financial position of the Company’s majority-owned subsidiaries are reported as non-controlling interests. 
Intercompany accounts and transactions have been eliminated in consolidation. 

Use of Estimates 

The preparation of financial statements in accordance with generally accepted accounting principles in the United States of 

America (“GAAP”) requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, 
and the disclosure of contingent assets and liabilities, at the date of the financial statements, as well as the reported amounts of 
revenues and expenses during the period. These estimates are based on historical experience and various other assumptions believed 
reasonable under the circumstances. The Company evaluates its estimates on an ongoing basis and makes changes to the estimates and 
related disclosures as experience develops or new information becomes known. Actual results may differ from those estimates. 

78

IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

Foreign Currencies 

The Company’s financial statements are reported in United States dollars and, accordingly, the Company’s results of 

operations are impacted by fluctuations in exchange rates that affect the translation of its revenues and expenses denominated in 
foreign currencies into United States dollars for purposes of reporting its consolidated financial results. Assets and liabilities recorded 
in foreign currencies on the books of foreign subsidiaries are translated at the exchange rate on the balance sheet date. Revenues, costs 
and expenses are translated at average rates of exchange during the year. Translation adjustments resulting from this process are 
charged or credited to the accumulated other comprehensive income (loss) (“AOCI”) component of stockholders’ equity (deficit). The 
Company is subject to foreign currency transaction risk for fluctuations in exchange rates during the period of time between the 
consummation and cash settlement of a transaction. The Company earns revenue from its service contracts over a period of several 
months and, in some cases, over a period of several years. Accordingly, exchange rate fluctuations during this period may affect the 
Company’s profitability with respect to such contracts. 

For operations outside the United States that are considered to be highly inflationary or where the United States dollar is 
designated as the functional currency, monetary assets and liabilities are remeasured using end-of-period exchange rates, whereas non-
monetary accounts are remeasured using historical exchange rates, and all remeasurement and transaction adjustments are recognized 
in other expense (income), net. Other expense (income), net, includes foreign currency net losses (gains) for 2017, 2016 and 2015 of 
approximately $40 million, $6 million and ($5) million, respectively. The foreign currency losses in 2017 were primarily the result of 
the combination of changes in intercompany loan balances from corporate legal entity integration and a weaker U.S. dollar.

Cash Equivalents 

The Company considers all highly liquid investments with an initial maturity of three months or less when purchased to be 

cash equivalents. 

Investments in Marketable Securities 

Investments in marketable securities are classified as either trading or available-for-sale and measured at fair market value. 

Realized and unrealized gains and losses on trading securities are included in other expense (income), net, on the accompanying 
consolidated statements of income. Realized gains and losses on available-for-sale securities are included in other expense (income), 
net, on the accompanying consolidated statements of income. Unrealized gains and losses, net of deferred income taxes, on available-
for-sale securities are included in the AOCI component of stockholders’ equity (deficit) until realized. Any gains or losses from the 
sales of investments or other-than-temporary declines in fair value are computed by specific identification. 

Equity Method Investments 

The Company’s investments in and advances to unconsolidated affiliates are accounted for under the equity method if the 
Company exercises significant influence or has an investment in a limited partnership that is considered to be greater than minor. 
These investments and advances are classified as investments in and advances to unconsolidated affiliates on the accompanying 
consolidated balance sheets. The Company records its pro rata share of the earnings, adjusted for accretion of basis difference, of these 
investments in equity in earnings of unconsolidated affiliates on the accompanying consolidated statements of income. The Company 
reviews its investments in and advances to unconsolidated affiliates for impairment whenever events or changes in circumstances 
indicate that the carrying amounts may not be recoverable.

79

IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued   

Derivatives 

The Company uses derivative instruments to manage exposures to interest rates and foreign currencies. Derivatives are 

recorded on the balance sheet at fair value at each balance sheet date utilizing pricing models for non-exchange-traded contracts. At 
inception, the Company designates whether or not the derivative instrument is an effective hedge of an asset, liability or firm 
commitment which is then classified as either a cash flow hedge or a fair value hedge. If determined to be an effective cash flow 
hedge, changes in the fair value of the derivative instrument are recorded as a component of AOCI until realized. The Company 
includes the impact from these hedges in the same line item as the hedged item on the consolidated statements of cash flows. Changes 
in fair value of effective fair value hedges are recorded in earnings as an offset to the changes in the fair value of the related hedged 
item. Hedge ineffectiveness, if any, is immediately recognized in earnings. Changes in the fair values of derivative instruments that 
are not an effective hedge are recognized in earnings. When it is probable that a hedged forecasted transaction will not occur, the 
Company discontinues hedge accounting for the affected portion of the forecasted transaction, and reclassifies gains or losses that 
were accumulated in AOCI to earnings in other expense (income), net for foreign exchange derivatives and interest expense for 
interest rate derivatives on the consolidated statements of income. Cash flows are classified consistent with the underlying hedged 
item. The Company has entered, and may in the future enter, into derivative contracts (caps, swaps, forwards, calls or puts, warrants, 
for example) related to its debt, investments in marketable equity securities and forecasted foreign currency transactions. 

Accrued Loyalty

The Company owns businesses that manage co-pay reimbursements on behalf of its pharmaceutical customers. These 
customers prefund the reimbursements and the Company includes this cash on its balance sheet. The Company draws on this cash to 
pay pharmacies as consumers use these programs. Accrued loyalty was $143 million and $131 million, as of December 31, 2017 and 
2016, respectively, and included within accrued expenses on the consolidated balance sheet.

Billed and Unbilled Services and Unearned Income 

In general, prerequisites for billings and payments are established by contractual provisions including predetermined payment 
schedules, which may or may not correspond to the timing of the performance of services under the contract. Unbilled services arise 
when services have been rendered for which revenue has been recognized but the clients have not been billed. 

In some cases, payments received are in excess of revenue recognized. Payments received in advance of services being 
provided are deferred as unearned income on the consolidated balance sheet. As the contracted services are subsequently performed 
and the associated revenue is recognized, the unearned income balance is reduced by the amount of the revenue recognized during the 
period. 

Allowance for Doubtful Accounts 

The Company’s allowance for doubtful accounts is determined based on a variety of factors that affect the potential 

collectability of the related receivables, including length of time the receivables are past due, client credit ratings, financial stability of 
the client, specific one-time events and client payment history. In addition, in circumstances where the Company is made aware of a 
specific client’s inability to meet its financial obligations, a specific allowance is established. The accounts are individually evaluated 
on a regular basis and reserves are established as deemed appropriate based on the above criteria. 

Receivables Financing Facility 

Advances received under the Company’s receivables financing facility are accounted for as borrowings secured by the 
receivables and included in net cash provided by financing activities. The Company services the collateralized accounts receivables 
and the cash flows for the underlying receivables are included in cash provided by operating activities. The collateralized accounts 
receivables are included in trade accounts receivable and unbilled services, net. 

80

IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

Business Combinations 

Business combinations are accounted for using the acquisition method of accounting. The identifiable assets acquired, the 

liabilities assumed, and any non-controlling interest in the acquiree are recorded at their estimated fair values on the date of the 
acquisition. Goodwill represents the excess of the purchase price over the estimated fair value of the net assets acquired, including the 
amount assigned to identifiable intangible assets. When a business combination involves contingent consideration, the Company 
recognizes a liability equal to the estimated fair value of the contingent consideration obligation at the date of the acquisition. 
Subsequent changes in the estimated fair value of the contingent consideration are recognized in earnings in the period of the change. 
Acquisition-related costs are expensed as incurred. The consolidated financial statements include the results of operations of business 
combinations since the acquisition date. 

Long-Lived Assets 

Property and equipment are stated at cost and are depreciated using the straight-line method over the shorter of the asset’s 

estimated useful life or the lease term, if related to leased property, as follows: 

Buildings and leasehold improvements
Equipment
Furniture and fixtures
Transportation equipment

3 - 40 years
3 - 10 years
5 - 10 years
3 - 20 years

Definite-lived identifiable intangible assets are amortized primarily using an accelerated method that reflects the pattern in 

which the Company expects to benefit from the use of the asset over its estimated remaining useful life as follows:

Trademarks and trade names
Contract backlog and client relationships
Software and related assets
Databases
Non-compete agreements and other

1 - 17 years
1 - 25 years
1 - 9 years
1 - 9 years
1 - 5 years

Goodwill and indefinite-lived identifiable intangible assets, which consist of a trade name, are not amortized but evaluated for 

impairment annually, or more frequently if events or changes in circumstances indicate an impairment. 

Included in software and related items is the capitalized cost of internal-use software used in supporting the Company’s 
business. Qualifying costs incurred during the application development stage are capitalized and amortized over their estimated useful 
lives. Costs are capitalized from completion of the preliminary project stage and when it is considered probable that the software will 
be used to perform its intended function, up until the time the software is placed into service. The Company recognized $134 million, 
$44 million and $38 million of amortization expense in 2017, 2016 and 2015, respectively, related to software and related assets. 

The carrying values of property, equipment and intangible and other long-lived assets are reviewed for recoverability if the 

facts and circumstances suggest that a potential impairment may have occurred. If this review indicates that carrying values will not be 
recoverable, as determined based on undiscounted cash flow projections, the Company will record an impairment charge to reduce 
carrying values to estimated fair value. See Note 17 for information regarding the impairment charges recognized in 2017 and 2016. 
During 2015, the Company recognized a $2 million impairment charge for long-lived assets related to a facility closure in Japan. 

81

 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued  

Revenue Recognition 

The Company recognizes revenue when all of the following conditions are satisfied: (1) there is persuasive evidence of an 

arrangement; (2) the service offering has been delivered to the client; (3) the collection of the fees is probable; and (4) the arrangement 
consideration is fixed or determinable. The Company’s arrangements are primarily service contracts that range in duration from a few 
months to several years. 

In some cases, contracts provide for consideration that is contingent upon the occurrence of uncertain future events. The 

Company recognizes contingent revenue when the contingency has been resolved and all other criteria for revenue recognition have 
been met. Cash payments made to clients as incentives to induce the clients to enter into service agreements with the Company are 
amortized as a reduction of revenue over the period the services are performed. The Company records revenues net of any tax 
assessments by governmental authorities, such as value added taxes, that are imposed on and concurrent with specific revenue 
generating transactions. The Company does not recognize revenue with respect to start-up activities including contract and scope 
negotiation, feasibility analysis and conflict of interest review associated with contracts. The costs for these activities are expensed as 
incurred.  

For the arrangements that include multiple elements, arrangement consideration is allocated to units of accounting based on 
the relative selling price. The best evidence of selling price of a unit of accounting is vendor-specific objective evidence (“VSOE”), 
which is the price the Company charges when the deliverable is sold separately. When VSOE is not available to determine selling 
price, management uses relevant third-party evidence (“TPE”) of selling price, if available. When neither VSOE nor TPE of selling 
price exists, management uses its best estimate of selling price considering all relevant information that is available without undue cost 
and effort. 

The Company derives the majority of its revenues in the Commercial Solutions segment from various information and 

technology service offerings. A typical information offerings arrangement (primarily under fixed-price contracts) may include an 
ongoing subscription-based deliverable for which revenue is recognized ratably as earned over the contract period, and/or a one-time 
delivery of data offerings for which revenue is recognized upon delivery, assuming all other criteria are met. The Company’s 
subscription arrangements typically have terms ranging from one to three years and are generally non-cancelable and do not contain 
refund-type provisions. Technology services offerings consist of a mix of small and large-scale services and consulting projects, 
multi-year outsourcing contracts and Software-as-a-Service (“SaaS”) licenses. These arrangements typically have terms ranging from 
several weeks to three years, with a majority having terms of one year or less. Revenues for services engagements where deliverables 
occur ratably over time are recognized on a straight-line basis over the term of the arrangement. Revenues from time and material 
contracts are recognized as the services are provided. Revenues from fixed price ad hoc services and consulting contracts are 
recognized either over the contract term based on the ratio of the number of hours incurred for services provided during the period 
compared to the total estimated hours to be incurred over the entire arrangement (efforts based), or upon delivery (completed 
contract). 

The majority of the Company’s contracts within the Research & Development Solutions segment are service contracts for 

clinical research that represent a single unit of accounting. The Company recognizes revenue on its clinical research services contracts 
as services are performed primarily on a proportional performance basis, generally using output measures that are specific to the 
service provided. Examples of output measures include among others, number of investigators enrolled, number of site initiation visits 
and number of monitoring visits completed. Revenue is determined by dividing the actual units of work completed by the total units of 
work required under the contract and multiplying that ratio by the total contract value. The total contract value, or total contractual 
payments, represents the aggregate contracted price for each of the agreed upon services to be provided. Changes in the scope of work 
are common, especially under long-term contracts, and generally result in a change in contract value. Once the client has agreed to the 
changes in scope and renegotiated pricing terms, the contract value is amended and revenue is recognized, as described above. To the 
extent that contracts involve multiple elements, the Company follows the allocation methodology described above and recognizes 
revenue for each unit of accounting on a proportional performance basis. Most contracts may be terminated upon 30 to 90 days notice 
by the client, however, in the event of termination, contract provisions typically require payment for services rendered through the 
date of termination, as well as for subsequent services rendered to close out the contract. 

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 IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued  

The Company derives the majority of its revenues in its Integrated Engagement Services segment on a fee-for-service basis to 

clients within the biopharmaceutical industry. Fees on these arrangements are billed based on a contractual per-diem or hourly rate 
basis and revenue is recognized primarily on a time and materials basis. Some of the Company’s Integrated Engagement Services 
contracts are multiple element arrangements, with elements including recruiting, training and deployment of sales representatives. The 
nature of the terms of these multiple element arrangements will vary based on the customized needs of the Company’s clients. For 
contracts that have multiple elements, the Company follows the allocation methodology described above and recognizes revenue for 
each unit of accounting on a time and materials basis. The Company’s Integrated Engagement Services contracts sometimes include 
variable fees that are based on a percentage of service sales (royalty payments). The Company recognizes revenue on royalty 
payments when the variable components become fixed or determinable and all other revenue recognition criteria have been met, 
which generally only occurs upon the sale of the underlying service(s) and upon the Company’s receipt of information necessary to 
make a reasonable estimate. 

Reimbursed Expenses 

The Company includes reimbursed expenses in total revenues and costs of revenue as the Company is deemed to be the 

primary obligor in the applicable arrangements. These costs include such items as payments to investigators and travel expenses for 
the Company’s clinical monitors and sales representatives. 

The Company has collection risk on contractually reimbursable expenses, and, from time to time, is unable to obtain 
reimbursement from the client for costs incurred. When such an expense is not reimbursed, it is classified as costs of revenue on the 
consolidated statements of income. 

Expenses 

The Company’s costs and expenses are comprised primarily of costs of revenue, reimbursed expenses and selling, general and 

administrative expenses. Costs of revenue include compensation and benefits for billable employees and personnel involved in 
production, data management and delivery, and the costs of acquiring and processing data for the Company’s information offerings; 
costs of staff directly involved with delivering technology-related services offerings and engagements, related accommodations and 
the costs of data purchased specifically for technology services engagements; and other expenses directly related to service contracts 
such as courier fees, laboratory supplies, professional services and travel expenses. As noted above, reimbursed expenses are 
comprised principally of payments to investigators who oversee clinical trials and travel expenses for the Company’s clinical monitors 
and sales representatives. Selling, general and administrative expenses include costs related to sales, marketing, and administrative 
functions (including human resources, legal, finance and general management) for compensation and benefits, travel, professional 
services, training and expenses for information technology (“IT”), facilities and depreciation and amortization.

Concentration of Credit Risk 

Financial instruments that subject the Company to credit risk primarily consist of cash and cash equivalents, marketable 

securities and accounts receivable. The Company maintains its cash and cash equivalent balances with high-quality financial 
institutions and, consequently, the Company believes that such funds are subject to minimal credit risk. Investment policies have been 
implemented that limit purchases of marketable securities to investment grade securities. Substantially all revenues for Commercial 
Solutions, Research & Development Solutions and Integrated Engagement Services are earned by performing services under contracts 
with various pharmaceutical, biotechnology, medical device and healthcare companies. The concentration of credit risk is equal to the 
outstanding accounts receivable and unbilled services balances, less the unearned income related thereto, and such risk is subject to 
the financial and industry conditions of the Company’s clients. The Company does not require collateral or other securities to support 
client receivables. Credit losses have been immaterial and reasonably within management’s expectations. No client accounted for 10% 
or more of consolidated revenues in 2017, 2016 or 2015. 

Restructuring Costs 

Restructuring costs, which primarily include termination benefits and facility closure costs, are recorded at estimated fair 

value. Key assumptions in determining the restructuring costs include the terms and payments that may be negotiated to terminate 
certain contractual obligations and the timing of employees leaving the Company. 

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IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

Merger Related Costs 

Merger related costs include the direct and incremental costs associated with business combinations including (i) acquisition 

related costs such as investment banking, legal, accounting and consulting fees (see Footnote 15), (ii) incremental compensation costs 
triggered under change in control provisions in executive employment agreements, (iii) compensation and related costs of employees 
100% dedicated to merger-related integration activities and (iv) severance and other termination costs associated with redundant 
employees. During 2016, the Company recognized $87 million of merger related costs, which includes $36 million of acquisition 
related costs. All of these costs are related to the Merger. Merger related costs for all other business combinations have been 
immaterial and are included within selling, general and administrative expenses on the consolidated statements of income. 

Legal Costs

Legal costs are expensed as incurred. 

Debt Fees

Fees incurred to issue debt are generally deferred and amortized as a component of interest expense over the estimated term of 

the related debt using the effective interest rate method. 

Contingencies 

The Company records accruals for claims, suits, investigations and proceedings when it is probable that a liability has been 

incurred and the amount of the loss can be reasonably estimated. The Company reviews claims, suits, investigations and proceedings 
at least quarterly and records or adjusts accruals related to such matters to reflect the impact and status of any settlements, rulings, 
advice of counsel or other information pertinent to a particular matter. Legal costs associated with contingencies are charged to 
expense as incurred. 

The Company is party to legal proceedings incidental to its business. While the outcome of these matters could differ from 
management’s expectations, the Company does not believe the resolution of these matters will have a material adverse effect to the 
Company’s financial statements. 

Income Taxes 

Income tax expense includes United States federal, state and international income taxes. Certain items of income and expense 

are not reported in income tax returns and GAAP financial statements in the same year. The income tax effects of these differences are 
reported as deferred income taxes. Valuation allowances are provided to reduce the related deferred income tax assets to an amount 
which will, more likely than not, be realized. In light of the newly enacted Tax Cuts and Jobs Act (the “Tax Act”), the Company no 
longer considers the undistributed earnings of its foreign subsidiaries to be indefinitely reinvested and records deferred income taxes 
on these earnings. The Company has provisionally recorded their U.S. deferred taxes based on the Federal corporate income tax rate 
of 21%. We are continuing to analyze aspects of the Tax Act and, therefore, have not finalized our accounting policy with respect to 
whether to (1) recognize deferred taxes for basis differences expected to reverse as Global Low Taxed Intangible Income (“GILTI”) or 
(2) account for GILTI as period costs if and when incurred. We have not recognized any deferred tax impacts related to GILTI or the 
Base Erosion Anti Abuse Tax (“BEAT”) on a provisional basis. Interest and penalties related to unrecognized income tax benefits are 
recognized as a component of income tax expense as discussed further in Note 18. 

Pensions and Other Postretirement Benefits 

The Company provides retirement benefits to certain employees, including defined benefit pension plans and postretirement 
medical plans. The determination of benefit obligations and expense is based on actuarial models. In order to measure benefit costs 
and obligations using these models, critical assumptions are made with regard to the discount rate, expected return on plan assets, cash 
balance crediting rate, lump sum conversion rate and the assumed rate of compensation increases. In addition, retiree medical care cost 
trend rates are a key assumption used exclusively in determining costs for the Company’s postretirement health care and life insurance 
benefit plans. Management reviews these critical assumptions at least annually. Other assumptions involve demographic factors such 
as turnover, retirement and mortality rates. Management reviews these assumptions periodically and updates them when their 
experience deems it appropriate to do so. 

84

IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

The discount rate is the rate at which the benefit obligations could be effectively settled and is determined annually by 

management. For United States plans, the discount rate is based on results of a modeling process in which the plans’ expected cash 
flow (determined on a projected benefit obligation basis) is matched with spot rates developed from a yield curve comprised of high-
grade (Moody’s Aa and above, or Standard and Poor’s AA and above) non-callable corporate bonds to develop the present value of 
the expected cash flow, and then determining the single rate (discount rate), which when applied to the expected cash flow derives that 
same present value. In the United Kingdom specifically, the discount rate is set based on the yields on a universe of high quality non-
callable corporate bonds denominated in the British Pound, appropriate to the duration of plan liabilities. For the non-United States 
plans, the discount rate is based on the current yield of an index of high quality corporate bonds. 

The Company estimates the service and interest cost components of net periodic benefit cost for the Company’s United States 
and United Kingdom pension benefit plans by utilizing a full yield curve approach in the estimation of these components by applying 
the specific spot rates along the yield curve used in the determination of the benefit obligation to each of the underlying projected cash 
flows based on time until payment. 

Under the United States qualified retirement plan, participants have a notional retirement account that increases with pay and 

investment credits. The rate used to determine the investment credit (cash balance crediting rate) varies monthly. At retirement, the 
account is converted to a monthly retirement benefit. 

In selecting an expected return on plan asset assumption, the Company considers the returns being earned by each plan 
investment category in the fund, the rates of return expected to be available for reinvestment and long-term economic forecasts for the 
type of investments held by the plan. The actual return on plan assets will vary from year to year versus this assumption. The 
Company believes it is appropriate to use long-term expected forecasts in selecting the expected return on plan assets. As such, there 
can be no assurance that the Company’s actual return on plan assets will approximate the long-term expected forecasts. While the 
Company believes that the assumptions used are reasonable, differences in actual experience or changes in assumptions may 
materially affect its pension and postretirement benefit obligations and future expense. 

The Company’s estimated long-term rate of return on plan assets is based on the principles of capital market theory that 

maintain that over the long run, prudent investment risk taking is rewarded with incremental returns and that combining non-
correlated assets can maximize risk adjusted portfolio returns. Long-term return estimates are developed by asset category based on 
actual class return data, historical relationships between asset classes and risk factors and peer plan data. Long-term return estimates 
for the Company’s United Kingdom pension plans are developed by asset category based on actual class return data, historical 
relationships between asset classes and risk factors. 

The Company utilizes a corridor approach to amortizing unrecognized gains and losses in the pension and postretirement 

benefit plans. Amortization occurs when the accumulated unrecognized net gain or loss balance exceeds the criterion of 10% of the 
larger of the beginning balances of the projected benefit obligation or the market-related value of the plan assets. The excess 
unrecognized gain or loss balance is then amortized using the straight-line method over the average remaining service life of active 
employees expected to receive benefits. 

Stock-based Compensation 

The Company accounts for stock-based compensation for stock options and stock appreciation rights under the fair value 

method and uses the Black-Scholes-Merton model to estimate the value of such stock-based awards granted to its employees and non-
executive directors. Expected volatility is based upon the historical volatility of a peer group for a period equal to the expected term, 
as the Company does not have adequate history to calculate its own volatility and believes the expected volatility will approximate the 
historical volatility of the peer group. The Company does not currently anticipate paying dividends. The expected term represents the 
period of time the grants are expected to be outstanding. The risk-free interest rate is based on the United States Treasury yield curve 
in effect at the time of the grant. 

The Company accounts for its stock-based compensation for restricted stock awards and restricted stock units based on the 

closing market price of the Company’s common stock on the date of grant. The Company accounts for its stock-based compensation 
for performance awards based on the closing market price of the Company’s common stock on the date of grant and upon the Monte 
Carlo simulation model. 

85

IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued  

Earnings Per Share 

The calculation of earnings per share is based on the weighted average number of common shares or common stock 

equivalents outstanding during the applicable period. The dilutive effect of common stock equivalents is excluded from basic earnings 
per share and is included in the calculation of diluted earnings per share. Potentially dilutive securities include outstanding stock 
options and unvested restricted stock units, restricted stock and performance awards. Employee equity share options, restricted stock 
units, restricted stock, performance awards and similar equity instruments granted by the Company are treated as potential common 
shares outstanding in computing diluted earnings per share. Diluted shares outstanding are calculated based on the average share price 
for each fiscal period using the treasury stock method. Under the treasury stock method, the amount the employee must pay for 
exercising stock options, the amount of compensation cost for future service that the Company has not yet recognized, and the amount 
of benefits that would be recorded in additional paid-in capital when the award becomes deductible for tax purposes are assumed to be 
used to repurchase shares. 

Treasury Stock 

The Company records treasury stock purchases under the cost method. Upon reissuance of treasury stock, amounts in excess 

of the acquisition cost are credited to additional paid in capital. If the Company reissues treasury stock at an amount below its 
acquisition cost and additional paid in capital associated with prior treasury stock transactions is insufficient to cover the difference 
between the acquisition cost and the reissue price, this difference is recorded in retained earnings. 

Recently Issued Accounting Standards 

Accounting pronouncements adopted 

In August 2016, the United States Financial Accounting Standards Board (“FASB”) issued new accounting guidance that 

eliminates the diversity in practice related to the cash flow classification of certain cash receipts and payments including debt 
prepayment or extinguishment payments, payments upon maturity of a zero coupon bond, payment of contingent liabilities arising 
from a business combination, proceeds from insurance settlements, distributions received from certain equity method investees, and 
cash flows related to beneficial interests obtained in a financial asset securitization. The new guidance designates the appropriate cash 
flow statement classification, including requirements to allocate certain components of these cash receipts and payments among 
operating, investing and financing activities.  In the absence of specific guidance, each separately identifiable cash source and use will 
be classified on the basis of the nature of the underlying cash flows. The Company adopted this new accounting guidance 
retrospectively on January 1, 2017. The adoption of this new accounting guidance did not have a material effect on the Company’s 
consolidated financial statements. 

In March 2016, the FASB issued new accounting guidance that simplifies several aspects of the accounting for employee 
stock-based compensation transactions, including the accounting for income taxes, forfeitures, statutory tax withholding requirements, 
and the classification of excess income tax benefits on the statement of cash flows. Under the new accounting guidance, excess 
income tax benefits related to stock-based awards are reflected as a reduction of income tax expense on the statements of income and 
as cash provided from operating activities on the statements of cash flows. In the prior periods, these tax benefits were reflected 
directly in additional paid in capital and as cash provided from financing activities. The Company adopted this new accounting 
guidance prospectively on January 1, 2017. The adoption of this new accounting guidance did not impact the Company’s recognition 
of its stock-based compensation expense or its presentation of cash flows related to employee taxes paid for withheld shares. 

Accounting pronouncements being evaluated 

In August 2017, the FASB issued new accounting guidance that will allow more financial and nonfinancial hedging strategies 

to be eligible for hedge accounting. It also amends the presentation and disclosure requirements and changes how companies assess 
hedge effectiveness. It is intended to more closely align hedge accounting with companies’ risk management strategies, simplify the 
application of hedge accounting, and increase transparency as to the scope and results of hedging programs. The new accounting 
guidance will be effective for the Company on January 1, 2019. The Company is currently evaluating the impact of this new 
accounting guidance on its consolidated financial statements.

86

IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

In March 2017, the FASB issued new accounting guidance that requires the service cost component of net periodic benefit cost 
be presented in the same income statement line item as other employee compensation costs, and requires that the other components of 
net periodic benefit expense be recognized in the non-operating section of the income statement. In addition, only the service cost 
component of net periodic benefit expense is eligible for capitalization when applicable.  The new standard requires retrospective 
application of the change in the income statement and prospective application for the capitalization of service cost in assets. The new 
standard permits previously disclosed components of net benefit costs as an estimation basis for applying the retrospective 
presentation as a practical expedient. The new accounting guidance will be effective for the Company on January 1, 2018. Utilizing 
the practical expedient based on amounts disclosed in Note 19, the Company will reclassify non-service components of net periodic 
benefit cost of $17 million and $3 million for 2017 and 2016, respectively, from selling, general and administrative expenses into 
other income, net.

In January 2017, the FASB issued new accounting guidance that changes the definition of a business to clarify when a set of 

assets does not constitute a business. Under the new definition, when substantially all of the fair value of gross assets acquired (or 
disposed of) is concentrated in a single identifiable asset or a group of similar identifiable assets, the set of assets is generally not a 
business. The new accounting guidance will be effective for the Company on January 1, 2018. The adoption of this new accounting 
guidance may result in more acquisitions being accounted for as asset acquisitions.

In February 2016, the FASB issued new accounting guidance that requires lessees to recognize almost all leases on their 

balance sheet as a right-of-use asset and a lease liability. The income statement will reflect lease expense for operating leases, and 
amortization and interest expense for financing leases. The new accounting guidance will be effective for annual reporting periods 
beginning after December 15, 2018. Early adoption is permitted. The Company is currently evaluating the impact of this new 
accounting guidance on its consolidated financial statements.

In January 2016, the FASB issued new accounting guidance that modifies how entities measure equity investments and present 
changes in the fair value of financial liabilities. The new accounting guidance will be effective for annual reporting periods beginning 
after December 15, 2017. Early adoption of the presentation guidance is permitted; however, early adoption of the recognition and 
measurement guidance is not permitted. The adoption of this new accounting guidance is not expected to have a material effect on the 
Company’s consolidated financial statements.

In May 2014, the FASB and the International Accounting Standards Board issued a converged standard on the recognition of 

revenue from contracts with clients. The objective of the new standard is to establish a single comprehensive revenue recognition 
model that is designed to create greater comparability of financial statements across industries and jurisdictions. Under the new 
standard, companies will be required to recognize revenue to depict the transfer of goods or services to clients in amounts that reflect 
the consideration to which the company will be entitled in exchange for those goods or services. The Company has concluded that the 
majority of the clinical trial arrangements will represent a single performance obligation.  The Company will account for revenue for 
this single performance obligation over time using project cost as an input method to measure progress. The Company will be required 
to use significant judgment in calculating its estimated costs at completion for each contract, and will be required to update these 
estimates on an ongoing basis, which may result in fluctuations in revenue recognized in any given period. The Company’s 
arrangements in the Commercial Solutions and Integrated Engagement Services segments are generally multiple element 
arrangements under which current rules require the deferral of revenue when payment on a delivered unit of accounting is contingent 
on performing on a future unit of accounting.  Under the new standard these arrangements will consist of multiple performance 
obligations and such deferral of revenue will in some cases be lower (or zero) when management determines that it is probable that 
performance on the future performance obligation will occur. Service revenues and reimbursed expenses revenues will be treated 
consistently and presented as one line on the consolidated statements of income for all segments. The new standard will require 
expanded disclosures on revenue recognition, including information about changes in assets and liabilities that result from contracts 
with clients. The new standard will be effective for annual reporting periods beginning after December 15, 2017. The Company will 
adopt the new standard on January 1, 2018. The Company will use the full retrospective approach to transition upon adoption, which 
will require the Company to recast each prior reporting period presented. 

The adoption of the new standard is expected to result in a revenue reduction of less than 1% in 2017 and the cumulative 
impact through 2017 is not expected to be material to total stockholders’ equity. The revenue impact of the new standard will be 
finalized upon adoption in the first quarter of 2018 and is therefore subject to change. 

87

IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

2. Accounts Receivable and Unbilled Services 

Accounts receivable and unbilled services consist of the following (in millions): 

Trade:

Billed
Unbilled services

Trade accounts receivable and unbilled services

Allowance for doubtful accounts

Trade accounts receivable and unbilled services, net

3. Investments – Debt, Equity and Other Securities 

Current 

December 31,

2017

2016

  $

  $

1,229    $
779   
2,008   
(15)  
1,993    $

998 
723 
1,721 
(14)
1,707  

The Company’s short-term investments in debt, equity and other securities consist primarily of trading investments in mutual 

funds that are measured at fair value with realized and unrealized gains and losses recorded in other expense (income), net, on the 
accompanying consolidated statements of income. 

Long-term 

The Company’s long-term investments in debt, equity and other securities consist primarily of cost method investments.

The Company reviews the carrying value of each individual investment at each balance sheet date to determine whether or not 

an other-than-temporary decline in fair value has occurred. The Company employs alternative valuation techniques including the 
following: (i) the review of financial statements, including assessments of liquidity, (ii) the review of valuations available to the 
Company prepared by independent third parties used in raising capital, (iii) the review of publicly available information including 
press releases and (iv) direct communications with the investee’s management, as appropriate. If the review indicates that such a 
decline in fair value has occurred, the Company adjusts the carrying value to the estimated fair value of the investment and recognizes 
a loss for the amount of the adjustment. 

4. Investments in and Advances to Unconsolidated Affiliates 

The Company accounts for its investments in and advances to unconsolidated affiliates under the equity method of accounting 
and records its pro rata share of its losses or earnings from these investments in equity in earnings (losses) of unconsolidated affiliates. 
The following is a summary of the Company’s investments in and advances to unconsolidated affiliates (in millions): 

NovaQuest Pharma Opportunities Fund III, L.P.
NovaQuest Pharma Opportunities Fund IV, L.P.
CenduitTM
NostraData Pty Ltd.
Other

NovaQuest Pharma Opportunities Funds 

December 31,

2017

2016

33    $
7   
14   
8   
8   
70    $

43 
6 
11 
8 
1 
69  

  $

  $

The Company has committed to invest up to $50 million as a limited partner in NovaQuest Pharma Opportunities Fund III, 

L.P. (“Fund III”). As of December 31, 2017, the Company has funded approximately $43 million and has approximately $7 million of 
remaining funding commitments. As of December 31, 2017 and 2016, the Company had a 10.9% ownership interest in Fund III. 

88

 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

The Company has committed to invest up to $20 million as a limited partner in NovaQuest Pharma Opportunities Fund IV, 

L.P. (“Fund IV”). As of December 31, 2017, the Company has funded approximately $11 million and has approximately $9 million of 
remaining funding commitments. As of December 31, 2017 and 2016, the Company had a 2.3% ownership interest in Fund IV. 

Cenduit™ 

In May 2007, the Company and Thermo Fisher Scientific Inc. (“Thermo Fisher”) completed the formation of a joint venture, 
Cenduit™. The Company contributed its Interactive Response Technology operations in India and the United States. Thermo Fisher 
contributed its Fisher Clinical Services Interactive Response Technology operations in three locations — the United Kingdom, the 
United States and Switzerland. Additionally, each company contributed $4 million in initial capital. The Company and Thermo Fisher 
each own 50% of Cenduit™. Cenduit provides project related services to the Company on an as needed basis.

NostraData Pty Ltd.

In November 2015, IMS Health made a 10.25 million AUD (approximately 9 million USD) investment in NostraData Pty Ltd. 

(“NostraData”) for a 24% equity interest. NostraData provides data to the Company on an as needed basis.

See Note 20 for information regarding related party transactions. 

5. Variable Interest Entities 

As of December 31, 2017, the Company’s investments in unconsolidated variable interest entities (“VIEs”) and its estimated 

maximum exposure to loss were as follows (in millions): 

NovaQuest Pharma Opportunities Fund III, L.P.
NovaQuest Pharma Opportunities Fund IV, L.P.
Pappas Life Science Ventures V, L.P. (“Pappas Fund V”)

Investments in
Unconsolidated
VIEs

Maximum
Exposure to
Loss

  $

  $

33    $
7   
1   
41    $

40 
16 
5 
61  

The Company has determined that these funds are VIEs but that the Company is not the primary beneficiary as it does not 

have a controlling financial interest in these funds. However, because the Company has the ability to exercise significant influence, it 
accounts for its investments in these funds under the equity method of accounting and records its pro rata share of earnings and losses 
in equity in earnings (losses) of unconsolidated affiliates on the accompanying consolidated statements of income. The investment 
assets of unconsolidated VIEs are included in investments in and advances to unconsolidated affiliates on the accompanying 
consolidated balance sheets. 

6. Derivatives 

Foreign Exchange Risk Management 

The Company transacts business in more than 100 countries and is subject to risks associated with fluctuating foreign 
exchange rates. The Company’s objective is to reduce earnings and cash flow volatility associated with foreign exchange rate 
movements. Accordingly, the Company enters into foreign currency forward contracts to (i) hedge certain forecasted foreign exchange 
cash flows arising from service contracts (“Service Contract Hedging”) and (ii) hedge non-United States dollar anticipated 
intercompany royalties (“Royalty Hedging”). It is the Company’s policy to enter into foreign currency transactions only to the extent 
necessary to meet its objectives as stated above. The Company does not enter into foreign currency transactions for investment or 
speculative purposes. The principal currencies hedged are the Euro, the British Pound, the Japanese Yen, the Swiss Franc and the 
Canadian dollar.  

89

 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

 Service Contract Hedging and Royalty Hedging contracts are designated as hedges and are carried at fair value, with changes 

in the fair value recorded to AOCI. The change in fair value is reclassified from AOCI to earnings in the period in which the hedged 
transaction occurs. These contracts have various expiration dates through November 2018. 

As of December 31, 2017, the Company had 57 open Service Contract Hedging and Royalty Hedging contracts to hedge 
certain forecasted foreign currency cash flow transactions occurring in 2018 with notional amounts totaling $282 million. As of 
December 31, 2016, the Company had 62 open Service Contract Hedging and Royalty Hedging contracts to hedge certain forecasted 
foreign currency cash flow transactions occurring in 2017. For accounting purposes, these hedges are deemed to be highly effective. 
As of December 31, 2017 and 2016, the Company had recorded gross unrealized gains (losses) of $5 million and ($4) million and $11 
million and ($9) million, respectively, related to these contracts. Upon expiration of the hedge instruments in 2018, the Company will 
reclassify the unrealized gains and losses on the derivative instruments included in AOCI into earnings. The unrealized gains (losses) 
are included in other current assets and liabilities on the accompanying consolidated balance sheets as of December 31, 2017 and 
2016. 

Interest Rate Risk Management 

The Company purchases interest rate caps and has entered into interest rate swap agreements for purposes of managing its risk 

in interest rate fluctuations. 

On June 9, 2011, the Company entered into six interest rate swaps that expired between September 30, 2013 and March 31, 

2016, in an effort to limit its exposure to changes in the variable interest rate on its senior secured credit facilities. During May 2015, 
in conjunction with the debt refinancing described in Note 11, the Company terminated the remaining open interest rate swaps for a 
cash payment to the counterparty of $12 million, which includes $1 million of accrued interest. Since the hedged forecasted cash 
transactions continued to be probable of occurring, the accumulated loss ($3 million at December 31, 2015) related to the terminated 
interest rate swaps in AOCI was reclassified to earnings as a component of interest expense in the same periods as the hedged 
forecasted transactions occurred over the first three months of 2016. 

In April 2014, IMS Health purchased United States dollar denominated interest rate caps (“2014 Caps”) with a total notional 

value of $1 billion at strike rates ranging between 2% and 3%. These caps were effective at various times between April 2014 and 
April 2016, and expire at various times between April 2017 and April 2019. The total premiums were $21 million, which were paid in 
2014. The 2014 Caps are designated as cash flow hedges. 

IMS Health also entered into United States dollar and Euro denominated interest rate swap agreements in April 2014 (“2014 
Swaps”) to hedge interest rate exposure on notional amounts of approximately $600 million of its borrowings. The 2014 Swaps were 
effective between April and June 2014, and expire at various times from March 2017 through March 2021. On these agreements, the 
Company pays a fixed rate ranging from 1.4% to 2.1% and receives a variable rate of interest equal to the greater of three-month 
United States dollar London Interbank Offered Rate (“LIBOR”) or three-month Euro Interbank Offered Rate (“EURIBOR”), and 1%. 
The 2014 Swaps are designated as cash flow hedges. 

On June 3, 2015, the Company entered into seven forward starting interest rate swaps (“2015 Swaps”) in an effort to limit its 

exposure to changes in the variable interest rate on its senior secured credit facilities. Interest on the swaps began accruing on June 30, 
2016 and the interest rate swaps currently outstanding expire between March 31, 2018 and March 31, 2020. The Company pays a 
fixed rate ranging from 1.6% to 2.1% and receives a variable rate of interest equal to the three-month LIBOR on these agreements. 

90

IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

The critical terms of the 2015 Swaps are substantially the same as the underlying borrowings. These interest rate swaps are 

being accounted for as cash flow hedges as these transactions were executed to hedge the Company’s interest payments and for 
accounting purposes these hedges are highly effective. As such, the effective portion of the hedges is recorded as unrealized gains 
(losses) on derivatives included in AOCI and the ineffective portion of the hedges is recognized in earnings. The 2014 EUR Swap 
(notional value $347 million) ceased to be considered a highly effective hedge for accounting purposes when the underlying debt was 
refinanced on March 7, 2017. As such, the Company discontinued hedge accounting on that date and prospective changes in the fair 
value of the 2014 EUR Swap are recognized in earnings. The 2014 USD Swap (notional value $100 million) ceased to be considered a 
highly effective hedge for accounting purposes during the third quarter of 2017 and as such, the Company has discontinued hedge 
accounting and prospective changes in the fair value of the 2014 USD Swap are recognized in earnings.  The fair value of these 
interest rate swaps represents the present value of the anticipated net payments the Company will make to the counterparty, which, 
when they occur, are reflected as interest expense on the consolidated statements of income. These interest rate swaps will result in a 
total debt mix of approximately 55% fixed rate debt and 45% variable rate debt, before the additional protection arising from the 
interest rate caps.

Net Investment Risk Management 

Beginning in 2016, the Company designated its foreign currency denominated debt as a hedge of its net investment in foreign 

subsidiaries to reduce the volatility in stockholders’ equity caused by changes in the Euro exchange rate with respect to the United 
States dollar. As of December 31, 2017, these borrowings (net of original issue discount) were €4,036 million ($4,835 million). The 
effective portion of foreign exchange gains or losses on the remeasurement of the debt is recognized in the cumulative translation 
adjustment component of AOCI with the related offset in long-term debt. Those amounts would be reclassified from AOCI to earnings 
upon the sale or substantial liquidation of these net investments. The amount of foreign exchange losses related to the net investment 
hedge included in cumulative translation adjustment for the year ended December 31, 2017 was $557 million. 

The fair values of the Company’s derivative instruments and the line items on the accompanying consolidated balance sheets 

to which they were recorded are summarized in the following table (in millions): 

Derivatives designated as hedging
   instruments:
Foreign exchange forward contracts

Interest rate swaps

Interest rate caps

Derivatives not designated as hedging
   instruments:
Interest rate swaps

Foreign exchange forward contracts

Balance Sheet
Classification

Other current assets
and liabilities
Other current
liabilities
Deposits and other
assets

Other current
liabilities
Other current
liabilities

December 31, 2017

December 31, 2016

  Assets

  Liabilities  

  Notional  

  Assets

  Liabilities  

  Notional  

  $

5    $

4    $

282    $

11    $

9    $

300 

—     

1     

405     

—     

15     

945 

1     

—     

700     

1     

—     

1,000 

—   

8   

447     

— 

— 

— 

—     

—     

—     

—     

1     

189 

Total derivatives

  $

6    $

13     

     $

12    $

25     

The effect of the Company’s cash flow hedging instruments on other comprehensive income (loss) is summarized in the 

following table (in millions): 

Foreign exchange forward contracts
Interest rate derivatives

Total

2017

Year Ended December 31,
2016

2015

  $

  $

(5)   $
9     
4    $

16    $
8     
24    $

(1)
6 
5  

91

 
 
 
 
 
 
 
 
 
 
 
 
    
      
      
      
      
      
  
 
 
   
 
   
   
   
      
      
      
  
  
  
  
  
 
   
  
  
 
   
 
   
   
      
      
      
      
      
  
   
  
 
 
 
 
 
 
 
 
 
 
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

The Company expects $1 million of pre-tax unrealized losses related to its foreign exchange contracts and interest rate 

derivatives included in AOCI at December 31, 2017 to be reclassified into earnings within the next twelve months. 

7. Fair Value Measurements 

The Company records certain assets and liabilities at fair value. Fair value is defined as the price that would be received to sell 

an asset or paid to transfer a liability in the principal or most advantageous market for the asset or liability in an orderly transaction 
between market participants at the measurement date. A three-level fair value hierarchy that prioritizes the inputs used to measure fair 
value is described below. This hierarchy requires entities to maximize the use of observable inputs and minimize the use of 
unobservable inputs. The three levels of inputs used to measure fair value are as follows: 

•

• 

• 

Level 1—Quoted prices in active markets for identical assets or liabilities. 

Level 2—Observable inputs other than quoted prices included in Level 1, such as quoted prices for similar assets and 
liabilities in active markets; quoted prices for identical or similar assets and liabilities in markets that are not active; or 
other inputs that are observable or can be corroborated by observable market data. 

Level 3—Unobservable inputs that are supported by little or no market activity. This includes certain pricing models, 
discounted cash flow methodologies and similar techniques that use significant unobservable inputs. 

The carrying values of cash, cash equivalents, accounts receivable and accounts payable approximated their fair values at 
December 31, 2017 and 2016 due to their short-term nature. At December 31, 2017 and 2016, the fair value of total debt approximated 
$10,432 million and $7,298 million, respectively, as determined under Level 2 measurements based on quoted prices for these 
financial instruments. 

Recurring Fair Value Measurements 

The following table summarizes the fair value of the Company’s financial assets and liabilities that are measured on a 

recurring basis as of December 31, 2017 (in millions): 

Assets:
Marketable securities
Derivatives
Total

Liabilities:
Derivatives
Contingent consideration

Total

Level 1

Level 2

Level 3

Total

  $

  $

  $

  $

46    $
—     
46    $

—    $
—     
—    $

—    $
6     
6    $

13    $
—     
13    $

—    $
—     
—    $

—    $
69     
69    $

The following table summarizes the fair value of the Company’s financial assets and liabilities that are measured on a 

recurring basis as of December 31, 2016 (in millions): 

Assets:
Marketable securities
Derivatives
Total

Liabilities:
Derivatives
Contingent consideration

Total

Level 1

Level 2

Level 3

Total

40    $
—     
40    $

—    $
—     
—    $

—    $
12     
12    $

25    $
—     
25    $

—    $
—     
—    $

—    $
18     
18    $

  $

  $

  $

  $

92

46 
6 
52 

13 
69 
82  

40 
12 
52 

25 
18 
43  

 
 
 
 
 
 
 
 
 
   
      
      
      
  
   
   
      
      
      
  
   
 
 
 
 
 
 
 
 
 
   
      
      
      
  
   
   
      
      
      
  
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued

Below is a summary of the valuation techniques used in determining fair value: 

Marketable securities—The Company values trading and available-for-sale securities using the quoted market value of the 

securities held. 

Derivatives—Derivatives consist of foreign exchange contracts and interest rate caps and swaps. The fair value of foreign 

exchange contracts is based on observable market inputs of spot and forward rates or using other observable inputs. The fair value of 
the interest rate caps and swaps is the estimated amount that the Company would receive or pay to terminate such agreements, taking 
into account market interest rates and the remaining time to maturities or using market inputs with mid-market pricing as a practical 
expedient for bid-ask spread. 

Contingent consideration—The Company values contingent consideration related to business combinations using a weighted 

probability calculation of potential payment scenarios discounted at rates reflective of the risks associated with the expected future 
cash flows. Key assumptions used to estimate the fair value of contingent consideration include revenue, net new business and 
operating forecasts and the probability of achieving the specific targets.

The following table summarizes the changes in Level 3 financial assets and liabilities measured on a recurring basis for the 

year ended December 31 (in millions): 

Contingent Consideration – Accrued Expenses
2016

2015

2017

Balance as of January 1
Business combinations
Contingent consideration paid
Revaluations included in earnings and foreign currency translation
   adjustments
Balance as of December 31

  $

  $

18    $
57     
(4)    

(2)    
69    $

4    $
19     
(4)    

(1)    
18    $

1 
— 
(3)

6 
4  

The revaluation for the contingent consideration is recognized in other expense (income), net on the accompanying 

consolidated statements of income.

Non-recurring Fair Value Measurements 

Certain assets are carried on the accompanying consolidated balance sheets at cost and are not remeasured to fair value on a 

recurring basis. These assets include cost and equity method investments and loans that are written down to fair value for declines that 
are deemed to be other-than-temporary, and goodwill and identifiable intangible assets that are tested for impairment annually and 
when a triggering event occurs. See Note 17 for additional information. 

As of December 31, 2017, assets carried on the balance sheet and not remeasured to fair value on a recurring basis totaled 

approximately $18,519 million and were identified as Level 3. These assets are comprised of cost and equity method investments of 
$78 million, goodwill of $11,850 million and other identifiable intangibles, net of $6,591 million. 

Cost and Equity Method Investments—The inputs available for valuing investments in non-public portfolio companies are 
generally not easily observable. The valuation of non-public investments requires significant judgment by the Company due to the 
absence of quoted market values, inherent lack of liquidity and the long-term nature of such assets. When a triggering event occurs, 
the Company considers a wide range of available market data when assessing the estimated fair value. Such market data includes 
observations of the trading multiples of public companies considered comparable to the private companies being valued as well as 
publicly disclosed merger transactions involving comparable private companies. In addition, valuations are adjusted to account for 
company-specific issues, the lack of liquidity inherent in a non-public investment and the fact that comparable public companies are 
not identical to the companies being valued. Such valuation adjustments are necessary because in the absence of a committed buyer 
and completion of due diligence similar to that performed in an actual negotiated sale process, there may be company-specific issues 
that are not fully known that may affect value. Further, a variety of additional factors are reviewed by the Company, including, but not 
limited to, financing and sales transactions with third parties, current operating performance and future expectations of the particular 
investment, changes in market outlook and the third-party financing environment. Because of the inherent uncertainty of valuations, 
estimated valuations may differ significantly from the values that would have been used had a ready market for the securities existed, 
and the differences could be material. 

93

 
 
 
 
 
 
 
 
 
 
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

Goodwill—Goodwill represents the difference between the purchase price and the fair value of the identifiable tangible and 
intangible net assets resulting from business combinations. The Company performs a qualitative analysis to determine whether it is 
more likely than not that the estimated fair value of a reporting unit is less than its book value. This includes a qualitative analysis of 
macroeconomic conditions, industry and market considerations, internal cost factors, financial performance, fair value history and 
other company specific events. If this qualitative analysis indicates that it is more likely than not that the estimated fair value is less 
than the book value for the respective reporting unit, the Company applies a two-step impairment test in which the Company 
determines whether the estimated fair value of the reporting unit is in excess of its carrying value. If the carrying value of the net 
assets assigned to the reporting unit exceeds the estimated fair value of the reporting unit, the Company performs the second step of 
the impairment test to determine the implied estimated fair value of the reporting unit’s goodwill. The Company determines the 
implied estimated fair value of goodwill by determining the present value of the estimated future cash flows for each reporting unit 
and comparing the reporting unit’s risk profile and growth prospects to selected, reasonably similar publicly traded companies. See 
Note 17 for additional information. 

Definite-lived Intangible Assets—If a triggering event occurs, the Company determines the estimated fair value of definite-

lived intangible assets by determining the present value of the expected cash flows. See Note 17 for additional information. 

Indefinite-lived Intangible Asset—If a qualitative analysis indicates that it is more likely than not that the estimated fair value 

is less than the carrying value of an indefinite-lived intangible asset, the Company determines the estimated fair value of the 
indefinite-lived intangible asset (trade name) by determining the present value of the estimated royalty payments on an after-tax basis 
that it would be required to pay the owner for the right to use such trade name. If the carrying amount exceeds the estimated fair value, 
an impairment loss is recognized in an amount equal to the excess. 

8. Property and Equipment 

The major classes of property and equipment were as follows (in millions): 

Land, buildings and leasehold improvements
Equipment
Furniture and fixtures
Transportation equipment
Property and equipment, gross
Less accumulated depreciation
Property and equipment, net

December 31,

2017

2016

324    $
446   
81   
72   
923   
(483)  
440    $

333 
338 
72 
26 
769 
(363)
406  

  $

  $

Property and equipment depreciation expense was as follows (in millions):

Depreciation expense

2017

Year Ended December 31,
2016

2015

  $

125    $

79    $

61  

94

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued

9. Goodwill and Identifiable Intangible Assets 

As of December 31, 2017, the Company has approximately $6,591 million of identifiable intangible assets, of which 

approximately $18 million, relating to a trade name, is deemed to be indefinite-lived and, accordingly, is not being amortized. 
Amortization expense associated with identifiable definite-lived intangible assets was as follows (in millions): 

Amortization expense

2017

Year Ended December 31,
2016

2015

  $

886    $

210    $

67  

Estimated amortization expense for existing identifiable intangible assets is expected to be approximately $983 million, $988 

million, $917 million, $765 million and $407 million for the years ending December 31, 2018, 2019, 2020, 2021 and 2022, 
respectively. Estimated amortization expense can be affected by various factors, including future acquisitions or divestitures of service 
and/or licensing and distribution rights or impairments. 

The following is a summary of identifiable intangible assets (in millions): 

As of December 31, 2017
Accumulated
Amortization   

Net
Amount

Gross
Amount

As of December 31, 2016
Accumulated
Amortization   

Net
Amount

Gross
Amount

Definite-lived identifiable intangible assets:
Client relationships and backlog
Trademarks, trade names and other
Databases
Software and related assets
Non-compete agreements

Indefinite-lived identifiable intangible assets:
Trade names(1)

  $

  $

  $

4,604    $
528     
1,876     
927     
24     
7,959    $

(474)   $
(59)    
(468)    
(382)    
(3)    
(1,386)   $

4,130    $
469     
1,408     
545     
21     
6,573    $

3,983    $
384     
1,742     
619     
9     
6,737    $

(125)   $
(15)    
(87)    
(247)    
—     
(474)   $

3,858 
369 
1,655 
372 
9 
6,263 

18    $

—    $

18    $

127    $

—    $

127  

(1)   In 2017, in conjunction with the Company’s name change from QuintilesIMS to IQVIA, the classification of the Quintiles trade name changed from an indefinite-

lived intangible asset to a definite-lived intangible asset.

The following is a summary of goodwill by segment for the years ended December 31, 2017 and 2016 (in millions): 

Commercial
Solutions

Research &
Development
Solutions

Integrated
Engagement
Services

Balance as of December 31, 2015
Business combinations
Impairment
Impact of foreign currency fluctuations and other
Balance as of December 31, 2016
Business combinations
Impairment
Impact of foreign currency fluctuations and other
Balance as of December 31, 2017

  $

  $

70    $
9,698     
(23)    
(330)    
9,415     
403     
(40)    
570     
10,348    $

602    $
611     
—     
(17)    
1,196     
178     
—     
11     
1,385    $

95

    Consolidated  
720 
10,376 
(23)
(346)
10,727 
581 
(40)
582 
11,850  

48    $
67     
—     
1     
116     
—     
—     
1     
117    $

 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
   
   
   
 
   
      
      
      
      
      
  
   
   
   
   
 
   
      
      
      
      
      
  
 
 
   
   
   
   
   
   
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

During the second quarter of 2017, the Company determined there was sufficient indication that the carrying value of Encore 

Health Resources LLC (“Encore”) should be reviewed for further impairment due to its continued decline in performance.  The 
Company performed an impairment assessment that resulted in the recognition of a goodwill impairment of $39.6 million, which 
represented the remaining amount of goodwill associated with Encore, and an intangible asset impairment of $0.4 million for declines 
in fair value.  On July 12, 2017, the Company completed the sale of Encore to an unrelated third party. As of December 31, 2017, 
accumulated goodwill impairment losses were $63 million, solely related to Encore.

During the year ended December 31, 2016, the Company recorded impairment losses of $28 million. See Note 17 for 

additional information.

10. Accrued Expenses

(in millions)
Compensation, including bonuses, fringe benefits and payroll taxes
Restructuring
Interest
Client contract related
Professional fees
Contingent consideration and deferred purchase price
Other

December 31,

2017

2016

  $

  $

656    $
84   
45   
565   
76   
59   
179   
1,664    $

610 
102 
42 
502 
69 
22 
146 
1,493  

11. Credit Arrangements 

The following is a summary of the Company’s revolving credit facilities at December 31, 2017: 

Facility
$1,000 million (revolving credit facility)

$25 million (receivables financing facility)
£10 million (approximately $13 million) general
   banking facility with a European headquartered
   bank

Interest Rates

  LIBOR in the relevant currency borrowed plus a margin (margin of

   2.00% at December 31, 2017)

  LIBOR Market Index Rate (1.56% at December 31, 2017) plus 0.90%
  Bank’s base rate (0.50% at December 31, 2017) plus 1%

96

 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

The following table summarizes the Company’s debt at the dates indicated (dollars in millions): 

Senior Secured Credit Facilities:

Term A Loan due 2021—U.S. Dollar LIBOR at average floating rates of 3.69%
Term A Loan due 2021—Euro LIBOR at average floating rates of 2.00%
Term B Loan due 2025—U.S. Dollar LIBOR at average floating rates of 3.69%
Term B Loan due 2024—U.S. Dollar LIBOR at average floating rates of 3.69%
Term B Loan due 2024—Euro LIBOR at average floating rates of 2.75%
Term B Loan due 2021—U.S. Dollar LIBOR at average floating rates of 3.50%
Term B Loan due 2021—Euro LIBOR at average floating rates of 3.75%

Revolving Credit Facility due 2021:

U.S. Dollar denominated borrowings—U.S. Dollar LIBOR at average floating
   rates of 3.47%

5.0% Senior Notes due 2026—U.S. Dollar denominated
2.875% Senior Notes due 2025—Euro denominated
3.25% Senior Notes due 2025—Euro denominated
3.5% Senior Notes due 2024—Euro denominated
4.125% Senior Notes due 2023—Euro denominated
4.875% Senior Notes due 2023—U.S. Dollar denominated
Receivables financing facility due 2020—U.S. Dollar LIBOR at average floating rate of
   2.46%
Principal amount of debt
Less: unamortized discount and debt issuance costs
Less: current portion
Long-term debt

  $

  $

Contractual maturities of long-term debt at December 31, 2017 are as follows (in millions): 

2018
2019
2020
2021
2022
Thereafter

December 31,

2017

2016

844    $
453   
748   
1,188   
1,423   
—   
—   

529   
1,050   
503   
1,707   
749   
—   
800   

275   
10,269   
(44)  
(103)  
10,122    $

  $

  $

888 
419 
— 
— 
— 
1,700 
765 

375 
1,050 
— 
— 
658 
289 
800 

275 
7,219 
(19)
(92)
7,108  

103 
103 
378 
1,652 
34 
7,999 
10,269  

At December 31, 2017, there were bank guarantees totaling approximately £3 million (approximately $4 million) issued 
against the availability of the general banking facility with a European headquartered bank through their operations in the United 
Kingdom. 

Senior Secured Credit Agreement and Senior Notes

2017 Financing Transactions

At December 31, 2017, the Company’s senior credit facility provided financing of up to approximately $5,656 million, which 

consisted of $5,185 million principal amount of debt outstanding (as detailed in the table above) and $471 million of available 
borrowing capacity on the $1.0 billion revolving credit facility that expires in 2021.

97

 
 
 
 
 
   
 
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued

On September 14, 2017, the Company’s wholly owned subsidiary, Quintiles IMS Incorporated (the “Issuer”), issued €420 
million (approximately $501 million) aggregate principal amount of 2.875% senior notes due 2025 (the “2025 Notes”). The 2025 
Notes, which are unsecured obligations of the Issuer, mature on September 15, 2025 and bear an interest rate of 2.875%, which is paid 
semi-annually on March 15 and September 15 of each year, beginning on March 15, 2018. The 2025 Notes may be redeemed prior to 
their final stated maturity, subject to a customary make-whole premium at any time prior to September 15, 2020 (subject to a certain 
customary “equity claw” redemption right) and thereafter subject to a redemption premium declining from 1.438% to 0%. On 
September 18, 2017, the Company amended its senior credit facility agreement (the “Amendment”) to provide for an incremental term 
B loan of $750 million and to increase the facility’s restricted payment capacity, specifically an increase to the total net leverage ratio 
conditions for unlimited restricted investments from 4.25-to-1.00 to 4.50-to-1.00 and for dividends and distributions from 4.00-to-1.00 
to 4.50-to-1.00. The new term B loan will mature in 2025 and bear a floating interest rate of LIBOR plus 2.00% per year.

On March 7, 2017, the Company refinanced all of its term B loans due 2021—U.S. dollar denominated (approximately $1,700 

million) and its term B loans due 2021—Euro denominated (approximately $765 million) with an extended and repriced term B loan 
facility due in 2024 for an aggregate principal amount of approximately $2,479 million comprised of $1,200 million U.S. dollar 
denominated term B loans and €1,200 million ($1,279 million) Euro denominated term B loans. The U.S. dollar denominated term B 
loans bear interest based on the U.S. Dollar LIBOR with a floor of 0.75%, plus a margin of 2.00% for an all-in interest rate of 3.69% 
as of December 31, 2017. The Euro denominated term B loans bear interest based on the Euro LIBOR with a floor of 0.75%, plus a 
margin of 2.00% for an all-in interest rate of 2.75% as of December 31, 2017. In connection with this refinancing, the Company 
recognized a $3 million loss on extinguishment of debt, which includes fees and related expenses.

On February 28, 2017, the Issuer issued €1,425 million (approximately $1,522 million) aggregate principal amount of 3.25% 

senior notes due 2025 (the “2017 Notes”). The 2017 Notes, which are unsecured obligations of the Issuer, mature on March 15, 2025 
and bear an interest rate of 3.25%, which is paid semi-annually on March 15 and September 15 of each year, beginning on September 
15, 2017. The 2017 Notes may be redeemed prior to their final stated maturity, subject to a customary make-whole premium at any 
time prior to March 15, 2020 (subject to a certain customary “equity claw” redemption right) and thereafter subject to annually 
declining redemption premiums at any time prior to March 15, 2022. During March 2017, the proceeds of the 2017 Notes were used to 
pay fees and expenses related to the notes offering and the refinancing referenced above and other general corporate purposes, 
including the repurchase of the Company’s common stock.

The net proceeds from the offering of the 2025 Notes and the Amendment referenced above were used to refinance certain 

indebtedness, including the redemption of the outstanding 4.125% Euro denominated senior notes due 2023 (the “4.125% Notes”), to 
pay down the revolving credit facility, to pay fees and expenses related to the offering of the 2025 Notes and the Amendment and for 
other general corporate purposes, including the repurchase of the Company’s common stock and acquisitions. In connection with this 
refinancing, the Company recognized a $16 million loss on extinguishment of debt, which includes the 4.125% Notes make-whole 
premium.  

2016 Financing Transactions

On October 3, 2016, the Company refinanced the term A loans due 2019 (approximately $884 million) assumed in the Merger 

with a term A loan facility due in 2021 for an aggregate principal amount of approximately $1,350 million comprised of both U.S. 
dollar denominated term A loans and Euro denominated term A loans. Additionally, the revolving credit facility was refinanced to an 
aggregate principal amount equal to $1.0 billion. The additional proceeds were used, in part, to fund the redemption on November 1, 
2016 of $500 million of 6% Senior Notes due 2020 assumed in the Merger, at a redemption price equal to 101.5% of the aggregate 
outstanding principal amount plus accrued interest to the redemption date. The Company incurred a loss on extinguishment of debt of 
approximately $8 million related to the aggregate payments for make-whole premiums.

98

IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

On September 28, 2016, IMS Health issued senior unsecured notes totaling principal amount of $1,750 million, which 

consisted of (i) $1,050 million of 5% senior notes due October 2026 (the “5% Dollar Notes”) and (ii) €625 million of 3.5% senior 
notes due October 2024 (the “3.5% Euro Notes” and, together with the 5% Dollar Notes, the “2016 Notes”). The proceeds of the 2016 
Notes, which the Company assumed upon closing of the Merger, were used on October 3, 2016 to repay in full ($1,389 million) the 
term loans outstanding under the Quintiles Transnational senior secured credit facilities. Interest on the 2016 Notes is payable semi-
annually, beginning on April 15, 2017. The notes are guaranteed on a senior unsecured basis by the Company’s wholly-owned 
domestic restricted subsidiaries (excluding IMS Japan K.K.) and, subject to certain exceptions, each of the Company’s future domestic 
subsidiaries that guarantees the Company’s other indebtedness or indebtedness of any of the guarantors. The 5% Dollar Notes and the 
3.5% Euro Notes may be redeemed, either together or separately, prior to their final stated maturity, subject to a customary make-
whole premium, at any time prior to October 15, 2021 with respect to the 5% Dollar Notes and October 15, 2019 with respect to the 
3.5% Euro Notes (in each case subject to a customary “equity claw” redemption right) and thereafter subject to annually declining 
redemption premiums at any time prior to October 15, 2024 with respect to the 5% Dollar Notes and October 15, 2021 with respect to 
the 3.5% Euro Notes.

The Company also assumed in the Merger €275 million of 4.125% Senior Notes due in April 2023 (the “4.125% Senior 

Notes”). As noted above, during the third quarter of 2017 the 4.125% Senior Notes were redeemed. Interest on the 4.125% Senior 
Notes was payable semi-annually each year and commenced on October 1, 2015. 

 Receivables Financing Facility 

On December 15, 2017, the Company amended its Receivables Financing Agreement to extend the original term of its 
receivables financing facility to December 15, 2020. In addition, the applicable margin (over LIBOR) changed to 90 bps regardless of 
the Company’s credit rating. Prior to the amendment, the margin was based on the Company’s credit rating and could range from 85 
bps to 135 bps. 

On December 5, 2014, the Company entered into a four-year arrangement to securitize certain of its accounts receivable. 

Under the receivables financing facility, certain of the Company’s accounts receivable are sold on a non-recourse basis by certain of 
its consolidated subsidiaries to another of its consolidated subsidiaries, a bankruptcy-remote special purpose entity (“SPE”). The SPE 
obtained a term loan and revolving loan commitment from a third-party lender, secured by liens on the assets of the SPE, to finance 
the purchase of the accounts receivable, which includes a $275 million term loan and a $25 million revolving loan commitment. The 
revolving loan commitment may be increased by an additional $35 million as amounts are repaid under the term loan. The Company 
has guaranteed the performance of the obligations of existing and future subsidiaries that sell and service the accounts receivable 
under the receivables financing facility. The assets of the SPE are not available to satisfy any of the Company’s obligations or any 
obligations of its subsidiaries. As of December 31, 2017, $25 million of revolving loans were available under the receivables financing 
facility. 

Restrictive Covenants 

The Company’s debt agreements provide for certain covenants and events of default customary for similar instruments, 

including a covenant not to exceed a specified ratio of consolidated senior secured net indebtedness to Consolidated EBITDA, as 
defined in the Company’s senior secured credit facility and a covenant to maintain a specified minimum interest coverage ratio. If an 
event of default occurs under any of the Company’s or the Company’s subsidiaries’ financing arrangements, the creditors under such 
financing arrangements will be entitled to take various actions, including the acceleration of amounts due under such arrangements, 
and in the case of the lenders under the revolving credit facility and New Term Loans, other actions permitted to be taken by a secured 
creditor. The Company’s long-term debt arrangements contain usual and customary restrictive covenants that, among other things, 
place limitations on the Company’s ability to declare dividends. For additional information regarding these restrictive covenants, see 
Part II, Item 5 “Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities—
Dividend Policy” and Part II, Item 7 “Management’s Discussion and Analysis of Financial Condition and Results of Operations—
Liquidity and Capital Resources” included elsewhere in this Annual Report on Form 10-K. At December 31, 2017, the Company was 
in compliance in all material respects with the financial covenants under the Company’s financing arrangements. 

99

IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

12. Leases

The Company leases facilities under operating leases, many of which contain renewal and escalation clauses. The Company 

also leases certain equipment and motor vehicles under operating leases. The leases expire at various dates through 2029 with options 
to cancel certain leases at various intervals. Rental expenses under these agreements were $197 million, $127 million and $109 million 
in 2017, 2016 and 2015, respectively. 

The following is a summary of future minimum payments under operating leases that have initial or remaining non-cancelable 

lease terms in excess of one year at December 31, 2017 (in millions): 

2018
2019
2020
2021
2022
Thereafter
Total minimum lease payments

13. Contingencies

Operating
Leases

169 
135 
115 
94 
75 
157 
745  

  $

  $

The Company and its subsidiaries are involved in legal and tax proceedings, claims and litigation arising in the ordinary course 

of business. Management periodically assesses the Company’s liabilities and contingencies in connection with these matters based 
upon the latest information available. For those matters where management currently believes it is probable that the Company will 
incur a loss and that the probable loss or range of loss can be reasonably estimated, the Company has recorded reserves in the 
consolidated financial statements based on its best estimates of such loss. In other instances, because of the uncertainties related to 
either the probable outcome or the amount or range of loss, management is unable to make a reasonable estimate of a liability, if any. 
However, even in many instances where the Company has recorded an estimated liability, the Company is unable to predict with 
certainty the final outcome of the matter or whether resolution of the matter will materially affect the Company’s results of operations, 
financial position or cash flows. As additional information becomes available, the Company adjusts its assessments and estimates of 
such liabilities accordingly. 

The Company routinely enters into agreements with its suppliers to acquire data and with its clients to sell data, all in the 

normal course of business. In these agreements, the Company sometimes agrees to indemnify and hold harmless the other party for 
any damages such other party may suffer as a result of potential intellectual property infringement and other claims related to the use 
of the data. The Company has not accrued a liability with respect to these matters, as the exposure is considered remote. 

Based on its review of the latest information available, management does not expect the impact of pending legal and tax 

proceedings, claims and litigation, either individually or in the aggregate, to have a material adverse effect on the Company’s results 
of operations, cash flows or financial position. However, one or more unfavorable outcomes in any claim or litigation against the 
Company could have a material adverse effect for the period in which it is resolved. The following is a summary of certain legal 
matters involving the Company. 

100

 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

The Company’s wholly-owned subsidiary, IMS Government Solutions Inc. (“IMS Government Solutions”), is primarily 

engaged in providing services under contracts with the United States government. United States government contracts are subject to 
extensive legal and regulatory requirements and, from time to time, agencies of the United States government have the ability to 
investigate whether contractors’ operations are being conducted in accordance with such requirements. IMS Government Solutions 
discovered potential noncompliance with various contract clauses and requirements under its General Services Administration 
Contract (the “GSA Contract”), which was awarded in 2002 to its predecessor company, Synchronous Knowledge Inc. (Synchronous 
Knowledge Inc. was acquired by IMS Health in May 2005). The potential noncompliance arose from two primary areas: first, at the 
direction of the government, work performed under one task order was invoiced under another task order without the appropriate 
modifications to the orders being made; and second, personnel who did not meet strict compliance with the labor categories 
component of the qualification requirements of the GSA Contract were assigned to contracts. The Company is currently unable to 
determine the outcome of all of these matters pending the resolution of the Voluntary Disclosure Program process and the ultimate 
liability arising from these matters could exceed the Company’s current reserves. 

On February 13, 2014, a group of approximately 1,200 medical doctors and 900 private individuals filed a civil lawsuit with 

the Seoul Central District Court against IMS Korea and two other defendants, KPA and the Korean Pharmaceutical Information 
Center (“KPIC”). The civil lawsuit alleges KPA and KPIC collected their personal information in violation of applicable privacy laws 
without the necessary consent through a software system installed on pharmacy computer systems in Korea, and that personal 
information was transferred to IMS Korea and sold to pharmaceutical companies. On September 11, 2017, the District Court issued a 
final decision that the encryption in use by the defendants since June 2014 was adequate to meet the requirements of the Korean 
Personal Information Privacy Act (“PIPA”) and the sharing of non-identified information for market research purposes was allowed 
under PIPA. The District Court also found an earlier version of encryption was insufficient to meet PIPA requirements, but no 
personal data had been leaked or re-identified. The District Court did not award any damages to plaintiffs. Approximately 280 medical 
doctors and 200 private individuals appealed the District Court decision. The Company believes the appeal is without merit and 
intends to vigorously defend its position.   

On July 23, 2015, indictments were issued by the Seoul Central District Prosecutors’ Office in South Korea against 24 

individuals and companies alleging improper handling of sensitive health information in violation of, among others, South Korea’s 
Personal Information Protection Act. IMS Korea and two of its employees were among the individuals and organizations indicted. 
Although there is no assertion that IMS Korea used patient identified health information in any of its offerings, prosecutors allege that 
certain of IMS Korea’s data suppliers should have obtained patient consent when they converted sensitive patient information into 
non-identified data and that IMS Korea had not taken adequate precautions to reduce the risk of re-identification. The Company 
believes the indictment is without merit as it acted in compliance with all applicable laws at all times and intends to vigorously defend 
its position. 

On January 10, 2017, IQVIA Inc., IMS Health Incorporated and IMS Software Services, Inc. (collectively “IQVIA Parties”) 

filed a lawsuit in the U.S. District Court for the District of New Jersey against Veeva Systems, Inc. (“Veeva”) alleging Veeva 
unlawfully used IQVIA Parties intellectual property to improve Veeva data offerings, to promote and market Veeva data offerings and 
to improve Veeva technology offerings. IQVIA Parties seek injunctive relief, appointment of a monitor, the award of compensatory 
and punitive damages and reimbursement of all litigation expenses, including reasonable attorneys’ fees and costs. On March 13, 
2017, Veeva filed counterclaims alleging anticompetitive business practices in violation of the Sherman Act and state laws. Veeva 
claims damages in excess of $200 million, and is seeking punitive damages and litigation costs, including attorneys’ fees. The 
Company believes the counterclaims are without merit, reject all counterclaims raised by Veeva and intend to vigorously defend 
IQVIA Parties’ position and pursue the Company’s claims against Veeva.

101

IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

14. Stockholders’ Equity 

Preferred Stock 

The Company is authorized to issue 1.0 million shares of preferred stock, $0.01 per share par value. No shares of preferred 

stock were issued and outstanding as of December 31, 2017 or 2016. 

Equity Repurchase Program and Secondary Public Offerings

On October 30, 2013, the Company’s Board of Directors (the “Board”) approved an equity repurchase program (the 
“Repurchase Program”) authorizing the repurchase of up to $125 million of either the Company’s common stock or vested in-the-
money employee stock options, or a combination thereof. The Board increased the stock repurchase authorization under the 
Repurchase Program with respect to the repurchase of its common stock by $600 million, $1.5 billion, $1 billion and $1 billion in 
2015, November 2016, February 2017 and May 2017, respectively, which increased the total amount that has been authorized under 
the Repurchase Program to $4.225 billion. The Repurchase Program does not obligate the Company to repurchase any particular 
amount of common stock or vested in-the-money employee stock options, and it could be modified, extended, suspended or 
discontinued at any time.

During the year ended December 31, 2017, the Company repurchased 30,896,313 shares of its common stock, including 
repurchases both under and outside of the Repurchase Program at an average market price per share of $84.80 for an aggregate 
purchase price of approximately $2.6 billion. These amounts include shares of the Company’s common stock that it repurchased from 
certain of its principal stockholders in a private transaction and directly from underwriters in connection with three separate 
underwritten secondary public offerings described below.

In February 2017, the Company entered into a share repurchase agreement with certain of the Company’s principal 

stockholders under the Repurchase Program. Pursuant to that agreement, the Company purchased an aggregate of 9,677,420 shares of 
the Company’s common stock in a private transaction for an aggregate purchase price of approximately $750 million. This transaction 
was consummated on February 28, 2017. 

On May 24, 2017, an automatic shelf registration statement (including a prospectus) relating to the offering of an unspecified 
amount of common stock was filed by the Company with the Securities and Exchange Commission and became effective upon filing. 
The registration statement will expire three years after the date of filing. Additionally, in May, the Company completed an 
underwritten secondary public offering of 10,571,003 shares of its common stock held by certain of the Company’s principal 
stockholders (the “May Selling Stockholders”), of which the Company repurchased 3,571,003 shares for an aggregate purchase price 
of approximately $300 million. The Company did not offer any stock in this transaction and did not receive any proceeds from the sale 
of the shares by the May Selling Stockholders. Pursuant to an agreement with the underwriter, the Company’s per-share purchase 
price for repurchased shares was the same as the per-share purchase price payable by the underwriter to the May Selling Stockholders.

In September 2017, the Company completed an underwritten secondary public offering of 9,000,000 shares of its common 

stock held by certain of the Company’s principal stockholders (the “September Selling Stockholders”), of which the Company 
repurchased 4,000,000 shares for an aggregate purchase price of approximately $380 million. The Company did not offer any stock in 
this transaction and did not receive any proceeds from the sale of the shares by the September Selling Stockholders. Pursuant to an 
agreement with the underwriter, the Company’s per-share purchase price for repurchased shares was the same as the per-share 
purchase price payable by the underwriter to the September Selling Stockholders. 

In November 2017, the Company completed an underwritten secondary public offering of 10,000,000 shares of its common 

stock held by certain of the Company’s principal stockholders (the “November Selling Stockholders”), of which the Company 
repurchased 2,500,000 shares for an aggregate purchase price of approximately $255 million. These shares were repurchased outside 
of the Company’s existing Repurchase Program. The Company did not offer any stock in this transaction and did not receive any 
proceeds from the sale of the shares by the November Selling Stockholders. Pursuant to an agreement with the underwriter, the 
Company’s per-share purchase price for repurchased shares was the same as the per-share purchase price payable by the underwriter 
to the November Selling Stockholders. 

102

IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

As of December 31, 2017, the Company has remaining authorization to repurchase up to $182 million of its common stock 

under the Repurchase Program. In addition, from time to time, the Company has repurchased and may continue to repurchase common 
stock through private or other transactions outside of the Repurchase Program. In February 2018, the Board authorized an increase of 
the share repurchase authorization by $1.5 billion. See Note 27 for additional information regarding this authorization increase. 

Below is a summary of the share repurchases made both under and outside of the Repurchase Program (in millions, except per 

share data): 

Number of shares of common stock repurchased
Aggregate purchase price
Average price per share

Non-controlling Interests 

2017

Year Ended December 31,
2016

2015

  $
  $

30.9     
2,620    $
84.80    $

14.3     
1,098    $
76.57    $

7.8 
516 
65.56  

As discussed further in Note 15, the Company contributed businesses to a joint venture with Quest Diagnostics Incorporated 

(“Quest”) that was recorded at book value (carryover basis) because the Company owns 60% of the joint venture and maintains 
control of these businesses. As a result, Quest’s non-controlling interest in the joint venture, referred to as Q2 Solutions, is equal to 
40%. Quest’s non-controlling interest was $249 million at December 31, 2017. 

15. Business Combinations 

IMS Health 

On October 3, 2016, pursuant to the terms of the Merger Agreement, IMS Health merged with and into Quintiles, with 
Quintiles continuing as the Surviving Corporation. The combination of Quintiles and IMS Health capabilities and resources creates an 
information and technology enabled healthcare service provider with a full suite of end-to-end clinical and commercial offerings. The 
Merger was accounted for as a business combination with Quintiles considered the accounting and the legal acquirer. Immediately 
prior to the completion of the Merger, Quintiles reincorporated as a Delaware corporation. The Surviving Corporation changed its 
name to Quintiles IMS Holdings, Inc. At the effective time of the Merger, IMS Health common stock was automatically converted 
into 0.3840 of a share of the Company’s common stock. In addition, IMS Health equity awards held by current employees and certain 
members of the former IMS Health board of directors were converted into the Company’s equity awards after giving effect to the 
exchange ratio. The terms of these awards, including vesting provisions, are substantially consistent to those of the historical IMS 
Health equity awards. All of the Company’s and IMS Health’s performance units outstanding at the date of the Merger were converted 
into restricted stock units with service based vesting requirements. The merger consideration was approximately $10.4 billion (based 
on the closing price of the Company’s common stock on October 3, 2016), and consisted of the fair value of the Company’s common 
stock issued (approximately 126.6 million shares) in exchange for the IMS Health common stock as well as the fair value of the vested 
portion of the converted IMS Health equity awards. The Merger-date value of former IMS Health stock-based awards was valued 
using the Black-Scholes-Merton model and apportioned between Merger consideration (purchase price) and unearned compensation to 
be recognized in expense as earned in future periods based on remaining service periods. In connection with the IMS Health 
acquisition, the Company recorded goodwill, primarily attributable to the assembled workforce of IMS Health and the expected 
synergies, which was assigned to the Commercial Solutions segment ($9,688 million), the Research & Development Solutions 
segment ($533 million) and the Integrated Engagement Services segment ($67 million). The goodwill is not deductible for income tax 
purposes. 

103

 
 
 
 
 
   
   
 
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

Quest 

On July 1, 2015, the Company and Quest closed on a joint venture transaction that resulted in the combination of their 
respective global clinical trials laboratory operations. The joint venture transaction was effected through the creation of two primary 
new legal entities that the Company controls. Both the Company’s and Quest’s clinical trials laboratory operations were contributed to 
these new legal entities. The Company accounted for the contribution of the Quest businesses as a business combination. Quest was 
issued a 40% equity interest in the legal entities, the fair value of which was $423 million on July 1, 2015 (40% of the fair value of all 
operations contributed by both parties) and represents the purchase price paid by the Company for the clinical trials laboratory 
operations that Quest contributed to the joint venture transaction. The resulting combined capabilities are designed to provide its 
clients with globally scaled end-to-end clinical trials laboratory services and the combined business is referred to and marketed as Q2 
Solutions. The Company accounted for the contribution of the Quest businesses as a business combination and consolidated the 
related new legal entities in its financial statements with a non-controlling interest for the portion owned by Quest. The Company 
recorded goodwill, primarily attributable to assembled workforce and expected synergies. This business combination is part of the 
Research & Development Solutions segment and the resulting goodwill is not deductible for income tax purposes. 

The following table summarizes the estimated fair value of the net assets acquired at the date of the acquisitions (in millions): 

IMS Health

Quest

Assets acquired:

Cash and cash equivalents
Accounts receivable and unbilled services
Prepaid expenses
Other current assets
Property and equipment
Goodwill
Other identifiable intangibles
Deferred income tax asset – long-term
Other long-term assets

Liabilities assumed:

Accounts payable and accrued expenses
Unearned income
Current portion of long-term debt
Other current liabilities
Long-term debt, less current portion
Deferred income tax liability – long-term
Other long-term liabilities

Net assets acquired

The other identifiable intangible assets consisted of the following (in millions): 

Client relationships
Backlog
Trade names
Databases
Software
Total other identifiable intangibles
Amortized over a weighted average useful life (in years)

  $

  $

  $

  $

2,031    $
528   
85   
145   
247   
10,288   
6,435   
25   
71   

(700)  
(175)  
(88)  
(45)  
(6,070)  
(2,104)  
(248)  
10,425    $

IMS Health

Quest

3,960    $
—   
385   
1,820   
270   
6,435    $
18   

32 
6 
1 
4 
16 
262 
126 
— 
— 

(13)
— 
— 
— 
— 
(10)
(1)
423  

74 
33 
19 
— 
— 
126 
9  

The acquired Quest trade name is an indefinite-lived intangible asset that is not amortized. 

104

 
 
 
 
 
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued

Acquisition Related Costs 

Acquisition related costs include the direct and incremental costs associated with mergers and acquisitions such as investment 

banking, legal, accounting and consulting fees. The Company recognized approximately $36 million of acquisition related costs 
associated with the IMS Health merger during the year ended December 31, 2016, which are included with merger related costs on the 
consolidated statement of income. Acquisition related costs for all other acquisitions were immaterial and are not presented. 

Unaudited Pro Forma Information 

The following unaudited pro forma information presents the financial results as if the acquisition of IMS Health had occurred 
on January 1, 2015 with pro forma adjustments to give effect to (i) an increase in depreciation and amortization expense for fair value 
adjustments of property, plant and equipment and intangible assets, (ii) an increase in stock-based compensation expense resulting 
from the exchange of the vested IMS Health equity awards for the Company’s equity awards and (iii) the related income tax effects. 
The pro forma results do not include any cost synergies, costs or other effects pertaining to the integration of IMS Health. 
Accordingly, such pro forma amounts are not necessarily indicative of the results that actually would have occurred for the periods 
presented below had the IMS Health acquisition been completed on January 1, 2015, nor are they indicative of the future operating 
results of the Company. 

The following table summarizes the pro forma results (in millions, except earnings per share): 

Revenues
Reimbursed expenses
Total revenues

Net income attributable to IQVIA Holdings Inc.
Earnings per share attributable to common stockholders:

Basic
Diluted

Year Ended December 31,

2016

2015

  $

  $
  $

  $
  $

7,784    $
1,514   
9,298    $
42    $

0.17    $
0.17    $

7,180 
1,411 
8,591 
450 

1.80 
1.76  

Pro forma information is not presented for any other acquisitions as the aggregate operations of the acquired businesses were 

not significant to the overall operations of the Company. 

The Company’s consolidated statements of income for the year ended December 31, 2016 includes $806 million of revenues 

related to the IMS Health acquisition. Following the closing of the IMS Health acquisition, the Company began integrating IMS 
Health’s operations. As a result, computing a separate measure of IMS Health’s stand-alone profitability for periods after the 
acquisition date is impracticable. 

Other Acquisitions 

The Company also completed a number of individually immaterial acquisitions during the year ended December 31, 2017. The 
Company’s assessment of fair value and the purchase price allocation related to these acquisitions is preliminary and subject to change 
upon completion. Further adjustments may be necessary as additional information related to the fair values of assets acquired and 
liabilities assumed is assessed during the measurement period (up to one year from the acquisition date). In addition to the merger with 
IMS Health in October 2016, the Company completed a few unrelated individually immaterial acquisitions during the fourth quarter 
of 2016. The accompanying consolidated financial statements include the results of the acquisitions subsequent to each respective 
closing date. 

105

 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
  
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

The following table provides certain financial information for these individually immaterial acquisitions, including the 

preliminary allocations of the purchase prices to certain tangible and intangible assets acquired and goodwill (in millions): 

Total cost of acquisitions, net of cash acquired(1)
Amounts recorded in the Consolidated Balance Sheets:

Goodwill
Portion of goodwill deductible for income tax purposes

Intangible assets:

Client relationships
Backlog
Non-compete agreements
Software
Trade names

Total intangible assets

Amortization
Period

2017

2016

   $

   $

6-16 years  $
1-4 years 
2-5 years 
2-9 years 
1-17 years 

   $

923    $

581    $
235   

285    $
15   
14   
61   
17   
392    $

136 

88 
— 

31 
7 
9 
1 
— 
48  

(1)  Total cost of acquisitions, net of cash acquired, includes contingent consideration and deferred purchase payments of $69 million. 

16. Restructuring 

From time to time, the Company takes restructuring actions to adapt to changing market conditions. These actions include 

closing facilities, consolidating functional activities, eliminating redundant positions, aligning resources with customer requirements 
and taking actions to improve process efficiencies. There were restructuring plans approved in each of 2017, 2016 and 2015 for these 
activities. Additionally, in 2016, the Company also acquired certain restructuring. 

The 2017 management approved plans resulted in approximately $61 million of restructuring expense, net of reversals, which 

consisted of severance, facility closure costs and other exit-related costs. The 2016 management approved plans resulted in 
approximately $33 million of restructuring expense, net of reversals, which consisted of severance, facility closure costs and other 
exit-related costs. The 2015 management approved plans resulted in approximately $23 million of restructuring expense, net of 
reversals, which consisted of severance, facility closure costs and other exit-related costs. Also during 2015, in connection with 
consummating the joint venture transaction with Quest, a restructuring plan was approved to reduce facility overcapacity and 
eliminate redundant roles. Since the start of this plan in 2015, the Company has recognized approximately $12 million of restructuring 
costs related to this plan.

The following amounts were recorded for the restructuring plans (in millions): 

Balance at December 31, 2015
Expense, net of reversals
Acquisitions
Payments
Foreign currency translation and other
Balance at December 31, 2016
Expense, net of reversals
Payments
Foreign currency translation and other
Balance at December 31, 2017

Severance and
Related Costs

Exit Costs

Total

  $

  $

12    $
60     
80     
(48)    
(5)    
99     
59     
(77)    
(1)    
80    $

2    $
3     
—     
(2)    
—     
3     
4     
(4)    
1     
4    $

14 
63 
80 
(50)
(5)
102 
63 
(81)
— 
84  

The reversals were due to changes in estimates primarily resulting from the redeployment of staff and higher than expected 

voluntary terminations. Restructuring costs are not allocated to the Company’s reportable segments as they are not part of the segment 
performance measures regularly reviewed by management. The Company expects the majority of the restructuring accruals at 
December 31, 2017 will be paid in 2018.

106

 
 
 
 
 
 
 
 
  
 
    
 
  
 
 
  
 
 
 
  
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

17. Impairment Charges 

During 2017 and 2016, the Company performed impairment assessments of Encore that resulted in the impairment of goodwill 
of $39.6 million and $23 million, respectively. These impairments represented the entire amount of goodwill associated with Encore.  
Encore had certain strategic initiatives not performing as expected, resulting in a decline in revenues. Additionally, as part of the 
respective impairment assessment, intangible asset impairments of $0.4 million and $5 million were recorded in 2017 and 2016, 
respectively. On July 12, 2017, the Company completed the sale of Encore to an unrelated third party. 

18. Income Taxes

On December 22, 2017, the U.S. government enacted the Tax Act. The Tax Act is comprehensive legislation that includes 

provisions that lower the federal corporate income tax rate from 35% to 21% beginning in 2018 and impose a one-time transition tax 
on undistributed foreign earnings. ASC 740 “Income Taxes” generally requires the effects of the tax law change to be recorded in the 
period of enactment. However, the SEC staff issued Staff Accounting Bulletin No. 118 to address situations when a registrant does not 
have the necessary information available, prepared, or analyzed (including computations) in reasonable detail to complete the 
accounting for certain income tax effects of the Tax Act. The Company has recognized the tax impacts related to the transition tax on 
undistributed foreign earnings and the impact to deferred tax assets and liabilities and included these amounts in its consolidated 
financial statements for the year ended December 31, 2017, on a provisional basis. The ultimate impact may differ from these 
provisional amounts, possibly materially, due to among other things, additional analysis, changes in interpretations and assumptions 
the Company has made, and additional interpretive regulatory guidance that may be issued. The accounting is expected to be complete 
when the 2017 U.S. corporate income tax return is filed in 2018.

The components of income before income taxes and equity in earnings (losses) of unconsolidated affiliates are as follows (in 

millions): 

Domestic
Foreign

2017

Year Ended December 31,
2016

2015

  $

  $

(495)   $
826     
331    $

(85)   $
564     
479    $

The components of income tax expense attributable to continuing operations are as follows (in millions): 

Current expense:

Federal and state
Foreign

Deferred (benefit) expense:

Federal and state
Foreign

2017

Year Ended December 31,
2016

2015

  $

  $

(3)   $
222     
219     

(1,165)    
(41)    
(1,206)    
(987)   $

64    $
129     
193     

166     
(14)    
152     
345    $

68 
471 
539  

51 
109 
160 

5 
(6)
(1)
159  

As a result of the Tax Act, the Company recorded a provisional deferred tax benefit of $977 million related to the revaluation 

of deferred taxes at the newly enacted 21% rate and reversal of the deferred tax liability on undistributed earnings net of the newly 
enacted transition tax. 

107

 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
   
      
      
  
   
 
   
   
      
      
  
   
   
 
   
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

The differences between the Company’s consolidated income tax expense attributable to continuing operations and the 

expense computed at the 35% United States statutory income tax rate were as follows (in millions):

Federal income tax expense at statutory rate
State and local income taxes, net of federal effect
Research and development
Foreign nontaxable interest income
United States taxes recorded on foreign earnings
Tax contingencies
Foreign rate differential
Equity compensation
Provisional Tax Act impact
Other

2017

Year Ended December 31,
2016

2015

  $

  $

116    $
(13)    
(9)    
(7)    
6     
17     
(95)    
(19)    
(977)    
(6)    
(987)   $

167    $
—     
(11)    
(8)    
252     
2     
(60)    
—     
—     
3     
345    $

189 
2 
(13)
(9)
38 
(8)
(49)
— 
— 
9 
159  

 In 2016, due to the Merger, the Company reevaluated its indefinite reinvestment assertion based on the need for cash in the 

United States, including funding the Repurchase Program and potential acquisitions. Accordingly, the Company changed its assertion 
with respect to $2,801 million of foreign earnings, including $1,865 million of IMS Health’s previously undistributed historical 
foreign earnings. Deferred income taxes of $625 million were recorded in 2016 related to non-indefinitely reinvested foreign 
earnings. Of that amount, $373 million was recorded through purchase accounting related to IMS Health’s historical foreign earnings 
and the remainder of $252 million was recorded through deferred income tax expense. 

Undistributed earnings of the Company’s foreign subsidiaries amounted to approximately $3,134 million at December 31, 

2017. With the enactment of the Tax Act, the Company does not consider any of its foreign earnings as indefinitely reinvested. The 
Company has recorded a provisional estimate of the deferred income tax liability for the transition tax, net of foreign tax credits, of 
$186 million as of December 31, 2017. 

The income tax effects of temporary differences from continuing operations that give rise to significant portions of deferred 

income tax assets (liabilities) are presented below (in millions): 

Deferred income tax assets:

Net operating loss and capital loss carryforwards
Tax credit carryforwards
Accrued expenses and unearned income
Employee benefits
Other

Valuation allowance for deferred income tax assets

Total deferred income tax assets
Deferred income tax liabilities:

Undistributed foreign earnings
Amortization and depreciation
Other

Total deferred income tax liabilities
Net deferred income tax liabilities

December 31,

2017

2016

  $

278    $
170   
46   
189   
82   
765   
(200)  
565   

(21)  
(1,334)  
(30)  
(1,385)  

  $

(820)   $

242 
267 
75 
273 
32 
889 
(153)
736 

(590)
(2,026)
(164)
(2,780)
(2,044)

108

 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
   
   
 
 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued

Due to the U.S. income tax rate decreasing from 35% to 21% per the Tax Act, the Company recorded a provisional reduction 

to its net deferred tax liabilities of $606 million, which includes a $753 million reduction to deferred tax liabilities that related to 
intangible amortization that was recorded through purchase accounting upon the Merger. In response to the Tax Act, the Company 
also reversed most of its deferred tax liability related to undistributed foreign earnings

The Company had federal, state and local, and foreign tax loss carryforwards and tax credits, the tax effect of which was $469 

million as of December 31, 2017. Of this amount, $34 million has an indefinite carryforward period, and the remaining $435 million 
expires at various times beginning in 2018. Some of these losses are subject to limitations under the Internal Revenue Code, however, 
management expects all losses to be utilized during the carryforward periods. 

In 2017, the Company increased its valuation allowance by $47 million to $200 million at December 31, 2017 from $153 

million at December 31, 2016. The valuation allowance increase is primarily related to an increase in the value of the U.S. state net 
operating losses as a result of the U.S. federal tax rate decreasing with the Tax Act.

A reconciliation of the beginning and ending amount of gross unrecognized income tax benefits is presented below (in 

millions): 

2017

Year Ended December 31,
2016

2015

Balance at January 1
IMS Health balance as of Merger
Additions based on tax positions related to the current year
Additions for income tax positions of prior years
Impact of changes in exchange rates
Settlements with tax authorities
Reductions for income tax positions of prior years
Reductions due to the lapse of the applicable statute of limitations
Balance at December 31

  $

  $

64    $
—     
11     
13     
4     
(2)    
(2)    
(6)    
82    $

30    $
37     
3     
7     
(3)    
—     
(1)    
(9)    
64    $

41 
— 
2 
9 
(1)
— 
(2)
(19)
30  

As of December 31, 2017, the Company had total gross unrecognized income tax benefits of $82 million associated with over 
100 jurisdictions in which the Company conducts business that, if recognized, would reduce the Company’s effective income tax rate. 

The Company’s policy for recording interest and penalties relating to uncertain income tax positions is to record them as a 
component of income tax expense in the accompanying consolidated statements of income. In 2017, 2016 and 2015, the amount of 
interest and penalties recorded as an addition/(reduction) to income tax expense in the accompanying consolidated statements of 
income was $3 million, $2 million and ($2) million, respectively. As of December 31, 2017 and 2016, the Company had accrued 
approximately $18 million and $11 million, respectively, of interest and penalties.

The Company believes that it is reasonably possible that a decrease of up to $10 million in gross unrecognized income tax 

benefits for federal, state and foreign exposure items may be necessary within the next 12 months due to lapse of statutes of 
limitations or uncertain tax positions being effectively settled. The Company believes that it is reasonably possible that a decrease of 
up to $1 million in gross unrecognized income tax benefits for foreign items may be necessary within the next 12 months due to 
payments. For the remaining uncertain income tax positions, it is difficult at this time to estimate the timing of the resolution.

109

 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

The Company conducts business globally and, as a result, files income tax returns in the United States federal jurisdiction and 
various state and foreign jurisdictions. In the normal course of business, the Company is subject to examination by taxing authorities 
throughout the world. The following table summarizes the tax years that remain open for examination by tax authorities in the most 
significant jurisdictions in which the Company operates: 

United States
India
Japan
United Kingdom
Switzerland

2014-2016
2006-2017
2012-2016
2016
2013-2016

In certain of the jurisdictions noted above, the Company operates through more than one legal entity, each of which has 

different open years subject to examination. The table above presents the open years subject to examination for the most material of 
the legal entities in each jurisdiction. Additionally, it is important to note that tax years are technically not closed until the statute of 
limitations in each jurisdiction expires. In the jurisdictions noted above, the statute of limitations can extend beyond the open years 
subject to examination. 

Due to the geographic breadth of the Company’s operations, numerous tax audits may be ongoing throughout the world at any 
point in time. Income tax liabilities are recorded based on estimates of additional income taxes that may be due upon the conclusion of 
these audits. Estimates of these income tax liabilities are made based upon prior experience and are updated in light of changes in facts 
and circumstances. However, due to the uncertain and complex application of income tax regulations, it is possible that the ultimate 
resolution of audits may result in liabilities that could be materially different from these estimates. In such an event, the Company will 
record additional income tax expense or income tax benefit in the period in which such resolution occurs. 

The Company had a tax holiday for Quintiles East Asia Pte. Ltd. in Singapore through June 2015. The income tax benefit of 

this holiday was approximately $2 million in 2015. The tax holiday increased earnings per share by approximately $0.02 in 2015. 

110

 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

19. Employee Benefit Plans 

Pension and Postretirement Benefit Plans 

The Company sponsors both funded and unfunded defined benefit pension plans. These plans provide benefits based on 

various criteria, including, but not limited to, years of service and salary. The Company also sponsors an unfunded postretirement 
benefit plan in the United States that provides health and prescription drug benefits to retirees who meet the eligibility requirements. 
The Company uses a December 31 measurement date for all pension and postretirement benefit plans.  

The following table summarizes changes in the benefit obligation, the plan assets and the funded status of the pension benefit 

plans (in millions): 

Obligation and funded status:
Change in benefit obligation
Projected benefit obligation at beginning of year   $
Service costs
Interest cost
Expected return on plan assets
Actuarial gains
Business combinations
Benefits paid
Contributions
Settlements
Foreign currency fluctuations and other
Projected benefit obligation at end of year
Change in plan assets
Fair value of plan assets at beginning of year
Actual return on plan assets
Contributions
Business combinations
Benefits paid
Settlements
Foreign currency fluctuations and other
Fair value of plan assets at end of year
Funded status

  $

United States Plans

Pension Benefits

December 31

Non-United States Plans

2017

2016

2017

2016

308    $
13   
11   
—   
25   
—   
(8)  
—   
—   
—   
349   

312   
53   
3   
—   
(8)  
—   
—   
360   
11    $

—    $
4   
3   
—   
(30)  
333   
(2)  
—   
—   
—   
308   

—   
5   
1   
308   
(2)  
—   
—   
312   

4    $

508    $
26   
9   
—   
(2)  
—   
(21)  
1   
(4)  
42   
559   

348   
17   
21   
—   
(21)  
(4)  
30   
391   
(168)   $

154 
18 
5 
— 
(8)
377 
(9)
— 
— 
(29)
508 

87 
4 
9 
284 
(9)
— 
(27)
348 
(160)

The following table summarizes the amounts recognized in the consolidated balance sheets related to the pension benefit plans 

(in millions): 

United States Plans

Pension Benefits

December 31

Non-United States Plans

2017

2016

2017

2016

Deposits and other assets
Accrued expenses
Other long-term liabilities
AOCI

  $

55    $
2   
42   
33   

45    $
1   
40   
29   

15    $
8   
175   
(3)  

13 
9 
164 
(8)

111

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
    
 
    
 
  
 
 
    
 
    
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
    
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

The following table summarizes the accumulated benefit obligation for all pension benefit plans (in millions): 

Accumulated benefit obligation

Pension Benefits

United States Plans

Non-United States Plans

December 31

2017

2016

2017

2016

  $

343    $

303    $

507    $

469  

 At December 31, 2017, the benefit obligation for other postretirement benefits was $3 million, with $1 million recorded in 

accrued expenses and $2 million included within other long-term liabilities. 

The following table provides the information for pension plans with an accumulated benefit obligation in excess of plan assets 

and projected benefit obligations in excess of plan assets (in millions): 

Pension Benefits

United States Plans

Non-United States Plans

December 31

2017

2016

2017

2016

Plans with accumulated benefit obligation in excess of plan assets:
Accumulated benefit obligation
Fair value of plan assets
Plans with projected benefit obligation in excess of plan assets:
Projected benefit obligation
Fair value of plan assets

  $

  $

45    $
3     

46    $
3     

43    $
2     

44    $
2     

442    $
301     

492    $
309     

409 
271 

444 
271  

The components of net periodic benefit cost changes in plan assets and benefit obligations recognized in other comprehensive 

loss were as follows (in millions): 

Service cost
Interest cost
Expected return on plan assets
Amortization of actuarial losses
Net periodic benefit cost
Other changes in plan assets and benefit obligations
   recognized in other comprehensive loss:
Actuarial loss (gain) – current years
Amortization of actuarial losses
Total recognized in other comprehensive income
Total recognized in net periodic benefit cost and other
   comprehensive loss

United States Plans

Non-United States Plans

Pension Benefits

2017

  $

Year Ended December 31,
2017

2016

2016

2015

13    $
11     
(24)    
—     
—     

(4)    
—     
(4)    

4    $
3     
(6)    
—     
1     

(29)    
—     
(29)    

26    $
9     
(14)    
1     
22     

(4)    
(1)    
(5)    

18    $
5     
(6)    
1     
18     

(5)    
(1)    
(6)    

$

(4)   $

(28)   $

17    $

12    $

15 
3 
(3)
1 
16 

— 
(1)
(1)

15  

112

 
 
 
 
 
   
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
   
 
 
 
 
 
 
   
   
   
 
   
      
      
      
  
   
   
      
      
      
  
   
 
 
 
 
 
   
 
 
 
 
 
 
   
   
   
   
 
   
   
   
   
 
 
      
      
      
      
  
   
   
   
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

The components of other changes in plan assets and benefit obligations recognized in other comprehensive loss related to the 

other postretirement benefits plan are de minimis. In addition, the amounts in AOCI that are expected to be recognized as components 
of net periodic benefit cost (credit) during 2018 for pension and other postretirement benefit plans are de minimis. 

Assumptions 

The weighted average assumptions used to determine net periodic benefit cost were as follows for the years ended 

December 31: 

Discount rate
Rate of compensation
    increases
Expected return on
   plan assets

Pension Benefits

  Other Postretirement Benefits  

United States Plans

2017

2016

2017

Non-United States Plans
2016

2015

2017

2016

4.17%   

3.62%   

1.89%   

1.88%   

2.46%   

2.90%   

2.40%

3.00%   

3.00%   

5.17%   

5.27%   

4.32%   

7.94%   

7.94%   

4.16%   

4.26%   

4.05%   

— 

— 

— 

—  

The weighted average assumptions used to determine benefit obligations were as follows at December 31: 

Discount rate
Rate of compensation
    increases

Pension Benefits

Other Postretirement Benefits

United States Plans

2017

2016

Non-United States Plans
2016
2017

2017

2016

3.69%   

4.17%   

1.90%   

1.68%   

2.90%   

2.90%

3.00%   

3.00%   

4.54%   

5.17%   

— 

—  

The discount rate represents the interest rate used to determine the present value of the future cash flows currently expected to 

be required to settle the Company’s defined benefit plan obligations. The discount rates are derived using weighted average yield 
curves on AA-rated corporate bonds. The cash flows from the Company’s expected benefit obligation payments are then matched to 
the yield curve to derive the discount rates. At December 31, 2017, the discount rate ranged from 2.90% to 3.73% for the Company’s 
United States pension plan and postretirement benefit plan. At December 31, 2017, the discount rate ranged from 2.22% to 2.53% for 
the Company’s United Kingdom pension plans. The United States and United Kingdom plans represent approximately 76% of the 
consolidated benefit obligation as of December 31, 2017. The discount rates in other non-U.S. countries ranged from 0.40% to 11.60% 
at December 31, 2017. 

The Company’s assumption for the expected return on plan assets was determined by the weighted average of the long-term 

expected rate of return on each of the asset classes invested as of the balance sheet date. For plan assets invested in government bonds, 
the expected return was based on the yields on the relevant indices as of the balance sheet date. There is considerable uncertainty for 
the expected return on plan assets invested in equity and diversified growth funds. The expected rate of return on plan assets for the 
United States pension plans was 7.75% at January 1, 2018. Outside the United States, the range of applicable expected rates of return 
was 1.0% to 6.46% as of January 1, 2018, compared to 0.8% to 9.0% as of January 1, 2017. The expected return on assets (“EROA”) 
was $38 million and $13 million and the actual return on assets was $70 million and $10 million for the years ended December 31, 
2017 and 2016, respectively.

113

 
 
 
 
 
 
 
 
  
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
   
 
 
   
 
 
 
 
 
 
 
 
 
 
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

Under the Company’s United States qualified retirement plan, participants have a notional retirement account that increases 
with pay and investment credits. The rate used to determine the investment credit (cash balance crediting rate) varies monthly and is 
equal to 1/12th of the yield on 30-year U.S. Government Treasury Bonds, with a minimum of 0.25%. At retirement, the account is 
converted to a monthly retirement benefit. 

At December 31, 2017, the Company’s health care cost trend rate for the next seven years was assumed to be 6.5% and the 

assumed ultimate cost trend rate was 5%. The Company assumed that ultimate cost trend rate is reached in 2021. 

Assumed health care cost trend rates could have a significant effect on the amounts reported for the health care plans. A one-
percentage-point change in assumed health care cost trend rates at December 31, 2017 would have a de minimis effect on the total of 
service and interest cost and on the accumulated postretirement benefit obligation. 

Plan Assets 

The Company’s pension plan weighted average asset allocations, by asset category, were as follows: 

Asset Category
Equity securities
Debt securities
Real estate
Other
Total

Plan Assets at December 31,

United States Plans
2016
2017

  Non-United States Plans

Total

2017

2016

2017

2016

69.86%   
25.21 
4.93 
— 

70.09%   
24.94 
4.97 
— 

47.92%   
14.65 
— 
37.43 

46.09%   
14.42 
— 
39.49 

58.44%   
19.71 
2.36 
19.49 

57.43%
19.39 
2.35 
20.83 

    100.00%    100.00%    100.00%    100.00%    100.00%    100.00%

The target asset allocation for the Company’s pension plans were as follows: 

Asset Category
Equity securities
Debt securities
Real estate
Other

United States
Plans

Non-United
States Plans

60-80% 
20-30% 
0-10% 
—% 

35-50% 
10-20% 
—% 
30-45% 

Total

45-65%
10-30%
0-5%
10-30%

The following table summarizes United States plan assets measured at fair value (in millions): 

Asset Category
Domestic equities
International equities
Corporate bonds
Real estate
Total assets in the fair value hierarchy
Common/collective trusts measured at net asset value
   (“NAV”)(1)
Total

  $

  $

Level 1

December 31, 2017
Level 2

Total

Level 1

December 31, 2016
Level 2

Total

37    $
23     
53     
18     
131     

—     
131    $

—    $
—     
—     
—     
—     

—     
—    $

37    $
23     
53     
18     
131     

229     
360    $

32    $
20     
46     
15     
113     

—     
113    $

—    $
—     
—     
—     
—     

—     
—    $

32 
20 
46 
15 
113 

199 
312  

114

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
 
 
 
 
 
 
 
 
 
   
 
 
   
   
   
   
   
 
   
   
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

The following table summarizes non-United States plan assets measured at fair value (in millions): 

Asset Category
International equities
Debt issued by national, state or local government
Diversified growth fund
Investments funds
Insurance contracts
Other
Total assets in the fair value hierarchy
Assets measured at NAV(1)
Total

  $

  $

Level 1

December 31, 2017
Level 2

Total

Level 1

December 31, 2016
Level 2

Total

—    $
2     
—     
—     
—     
—     
2     
—     
2    $

66    $
55     
17     
7     
141     
7     
293     
—     
293    $

66    $
57     
17     
7     
141     
7     
295     
96     
391    $

—    $
2     
—     
—     
—     
—     
2     
—     
2    $

57    $
48     
14     
7     
133     
6     
265     
—     
265    $

57 
50 
14 
7 
133 
6 
267 
81 
348  

(1)  Certain investments that are measured at fair value using the net asset value per share (or its equivalent) practical expedient have not been classified in the fair value 

hierarchy. The fair value amounts presented in the above plan asset tables are intended to permit reconciliation of the fair value of plan assets in the fair value 
hierarchy to the plan asset amounts presented in the above funded status table as of December 31, 2017 and 2016. 

Investments in mutual funds are valued at quoted market prices. Investments in common/collective trusts and pooled funds are 
valued at the NAV as reported by the trust. The NAV is based on the fair value of the underlying investments held by the fund less its 
liabilities. Insurance contracts are valued at the amount of the benefit liability. The Company has no Level 3 assets that rely on 
unobservable inputs to measure fair value. 

Investment Policies and Strategies 

The Company invests primarily in a diversified portfolio of equity and debt securities that provide for long-term growth within 
reasonable and prudent levels of risk. The asset allocation targets established by the Company are strategic and applicable to the plan’s 
long-term investing horizon. The portfolio is constructed and maintained to provide adequate liquidity to meet associated liabilities 
and minimize long-term expense and provide prudent diversification among asset classes in accordance with the principles of modern 
portfolio theory. The plan employs a diversified mix of actively managed investments around a core of passively managed index 
exposures in each asset class. Within each asset class, rapid market shifts, changes in economic conditions or an individual fund 
manager’s outlook may cause the asset allocation to fall outside the prescribed targets. The majority of the Company’s plan assets are 
measured quarterly against benchmarks established by the Company’s investment advisors and the Company’s Asset Management 
Committee, who review actual plan performance and have the authority to recommend changes as deemed appropriate. Assets are 
rebalanced periodically to their strategic targets to maintain the plan’s strategic risk/reward characteristics. The Company periodically 
conducts asset liability modeling studies to ensure that the investment strategy is aligned with the obligations of the plans and that the 
assets will generate income and capital growth to meet the cost of current and future benefits that the plans provide. The pension plans 
do not have investments in Company stock at December 31, 2017 or 2016. 

The portfolio for the Company’s United Kingdom pension plans seek to invest in a range of suitable assets of appropriate 
liquidity that will generate in the most effective manner possible, income and capital growth to ensure that there are sufficient assets to 
meet benefit payments when they fall due, while controlling the long-term costs of the plans and avoiding short-term volatility of 
investment returns. The plans seek to achieve these objectives by investing in a mixture of real (equities) and monetary (fixed interest) 
assets. It recognizes that the returns on real assets, while expected to be greater over the long-term than those on monetary assets, are 
likely to be more volatile. A mixture across asset classes should nevertheless provide the level of returns required by the plans. The 
trustee periodically conducts asset liability modeling exercises to ensure the investments are aligned with the appropriate benchmark 
to better reflect the plans’ liabilities. The trustee also undertakes to review this benchmark on a regular basis. 

115

 
 
   
 
 
   
   
   
   
   
 
   
   
   
   
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

Cash Flows 

Contributions 

The Company expects to contribute approximately $22 million in required contributions to its pension and postretirement 
benefit plans during 2018. The Company may make additional contributions into its pension plans in 2018 depending on, among other 
factors, how the funded status of those plans change or in order to meet minimum funding requirements as set forth in employee 
benefit and tax laws, plus additional amounts the Company may deem to be appropriate. 

Estimated future benefit payments and subsidy receipts 

The following benefit payments (net of expected participant contributions) for pension benefits are expected to be paid as 

follows (in millions): 

2018
2019
2020
2021
2022
Years 2023 through 2027

Pension Benefits

29 
30 
32 
35 
37 
218 
381  

  $

  $

Benefit payments (net of expected participant contributions) for other postretirement benefits are expected to be de minimis 

over the periods presented. 

Defined Contribution Plans 

Defined contribution or profit sharing plans are offered in Australia, Austria, Belgium, Bulgaria, Canada, the Czech Republic, 

Denmark, Finland, France, Germany, Greece, Hong Kong, Hungary, India, Ireland, Israel, Japan, Malaysia, the Netherlands, New 
Zealand, Poland, Slovakia, South Africa, Sweden, Switzerland, Taiwan, Thailand, the United States and the United Kingdom. In some 
cases, these plans are required by local laws or regulations. 

In the United States, the Company has 401(k) plans under which the Company matches employee deferrals at varying 
percentages and specified limits of the employee’s salary. In 2017, 2016 and 2015, the Company expensed $47 million, $39 million 
and $36 million, respectively, related to matching contributions. 

Certain key executives of the Company participate in an unfunded defined contribution executive retirement plan, assumed in 

the Merger, which was frozen to additional accruals for future service contributions in 2012. Participants continue to receive an annual 
investment credit based on the average of the annual yields at the end of each month on the AA-AAA rated 10 plus year maturity 
component of the Merrill Lynch United States Corporate Bond Master Index. 

Plans Accounted for as Postretirement Benefits 

The Company provides certain executives with postretirement medical, dental and life insurance benefits. These benefits are 
individually negotiated arrangements in accordance with their individual employment arrangements. The above tables do not include 
the Company’s expense or obligation associated with providing these benefits. The obligation related to these benefits was 
approximately $12 million for the year ended December 31, 2017, and the Company’s expense for the year then ended was de 
minimis.

116

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

Stock Incentive Plans 

Stock incentive plans provide incentives to eligible employees, officers and directors in the form of non-qualified stock 

options, incentive stock options, stock appreciation rights (“SARs”), restricted stock awards (“RSAs”), restricted stock units 
(“RSUs”), performance awards, covered annual incentive awards, cash-based awards and other stock-based awards, in each case 
subject to the terms of the stock incentive plans. 

In April 2017, the Company’s 2017 Incentive and Stock Award Plan (the “2017 Plan”) was approved by the Company’s 

stockholders. The 2017 Plan consolidates the unused share pools under the Company’s 2014 Incentive and Stock Award Plan (the 
“2014 Plan”), the Company’s 2013 Stock Incentive Plan (the “2013 Plan”), the Company’s 2010 Equity Incentive Plan (the “2010 
Plan”) and the Company’s 2008 Stock Incentive Plan (the “2008 Plan”), and together with the 2010 Plan, the 2013 Plan and the 2014 
Plan, the “Prior Plans,” and makes shares underlying outstanding awards granted under (but not ultimately delivered) the Prior Plans 
eligible for use in connection with new awards under the 2017 Plan.  The 2017 Plan provides for the grant of stock options, SARs, 
restricted and deferred stock (including RSUs), performance awards, dividend equivalents, other stock-based awards and cash-based 
awards. 

The fair value of stock options and SARs is estimated using the Black-Scholes-Merton option-pricing model. The fair value of 
restricted stock and RSUs is based on the closing market price of the Company’s common stock on the date of grant. The fair value of 
the performance shares is determined separately for the portion of the award based on compound annual earnings per share (“EPS”) 
growth and the portion of the award based on relative total shareholder return (“TSR”). The fair value of the compound annual EPS 
growth portion of the award is equal to the closing market price of the Company’s common stock on the date of grant. The fair value 
of the TSR portion of the award is determined based on a Monte Carlo simulation model. 

The Company recognized stock-based compensation expense of $106 million, $80 million and $38 million in 2017, 2016 and 

2015, respectively. Stock-based compensation expense is included in selling, general and administrative expenses on the 
accompanying consolidated statements of income. The associated future income tax benefit recognized was $21 million, $24 million 
and $9 million in 2017, 2016 and 2015, respectively. As of December 31, 2017, there was approximately $103 million of total 
unrecognized stock-based compensation expense related to outstanding non-vested stock-based compensation arrangements, which 
the Company expects to recognize over a weighted average period of 1.16 years. 

As of December 31, 2017, there were 13.4 million shares available for future grants under all of the Company’s stock 

incentive plans. 

The Company used the following assumptions when estimating the value of the stock-based compensation for stock options 

and SARs issued as follows: 

Expected volatility
Weighted average expected volatility
Expected dividends
Expected term (in years)
Risk-free interest rate

2017

Year Ended December 31,
2016

2015

22 – 25%  

20 – 30%  

26 – 41%  

24%
0.0%  

1.0 – 6.9
  1.16 – 2.32%  

28%
0.0%
0.3 – 6.6
  0.32 – 2.19%  

34%
0.0%
3.7 – 6.7
  1.06 – 2.04%  

117

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
   
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

Stock Options 

The option price is determined by the Board at the date of grant and the options expire 10 years from the date of grant. The 

vesting schedule for options granted to employees is either (i) 25% per year beginning on the first anniversary of the date of grant; or 
(ii) 33% on the third anniversary of the date of grant and 67% on the fourth anniversary of the date of grant. 

The Company’s stock option activity in 2017 is as follows (in millions, except number of options and exercise price): 

Outstanding at December 31, 2016

Exercised
Canceled

Outstanding at December 31, 2017

Number of
Options
7,251,339    $
(2,957,816)    
(212,891)    
4,080,632    $

Weighted
Average
Exercise Price

34.83    $
34.43     
57.03     
33.97    $

Aggregate

Intrinsic Value  
299 

261  

The weighted average fair value per share of the options granted in 2016 and 2015 was $17.91 and $21.96, respectively. The 

total intrinsic value of options exercised was approximately $157 million, $155 million and $144 million in 2017, 2016 and 2015, 
respectively. The Company received cash of approximately $102 million, $101 million and $59 million in 2017, 2016 and 2015, 
respectively, from options exercised. 

Selected information regarding the Company’s stock options as of December 31, 2017 is as follows: 

Options Outstanding

Options Exercisable

Number of
Options

827,775    $
1,219,780     
823,189     
839,003     
370,885    $

    $

Exercise Price Range
—
—
—
—
—

8.34     
18.40     
28.13     
44.45     
64.86     

    $

Weighted
Average
Exercise Price  

18.23    $
26.05     
42.74     
64.67     
77.11    $

11.15     
24.21     
33.07     
57.72     
65.28     

Weighted
Average
Remaining
Life
(in Years)

Number of
Options

2.54     
3.09     
4.59     
6.99     
7.12     

827,775    $
1,219,780     
751,032     
431,827     
172,635    $

Weighted
Average
Exercise Price  
11.15 
24.21 
33.52 
56.09 
65.31  

The weighted average remaining contractual life of the options outstanding and exercisable as of December 31, 2017 is 4.5 

years and 3.9 years, respectively. The total aggregate intrinsic value of the exercisable stock options and the stock options expected to 
vest as of December 31, 2017 was approximately $260 million. 

Stock Appreciation Rights – Stock Settled 

The exercise price of the stock-settled SARs (“SSRs”) is equal to the closing market price of the Company’s common stock as 
of the grant date and expire on the tenth anniversary of the date of grant. The SSRs are eligible to vest either (i) in equal increments of 
25% on each of the first four anniversaries of the date of grant or (ii) in three equal annual installments on each of the first three 
anniversaries of the date of grant. 

118

 
 
 
 
 
 
   
   
  
   
  
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
     
 
     
 
     
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

The Company’s SSR activity in 2017 is as follows (in millions, except number of SSRs and exercise price): 

Outstanding at December 31, 2016

Granted
Exercised
Canceled

Outstanding at December 31, 2017

Number of
Options
1,313,322    $
1,971,768     
(123,342)    
(236,978)    
2,924,770    $

Weighted
Average
Exercise Price

62.13    $
78.96     
63.24     
74.00     
72.47    $

Aggregate

Intrinsic Value  
18 

74  

The total intrinsic value of SSRs exercised was approximately $2.9 million in 2017. 

The weighted average remaining contractual life of the SSRs outstanding and exercisable as of December 31, 2017 is 8.5 years 

and 6.8 years, respectively. The total aggregate intrinsic value of the exercisable SSRs and the SSRs expected to vest as of 
December 31, 2017 was approximately $72 million. 

Stock Appreciation Rights – Cash Settled 

The Company’s cash settled SARs (“CSRs”) require the Company to settle in cash an amount equal to the difference between 

the fair value of the Company’s common stock on the date of exercise and the grant price, multiplied by the number of CSRs being 
exercised. These awards either (i) vest 25% per year or (ii) vest 33% on the third anniversary of the date of grant and 67% on the 
fourth anniversary of the date of grant; or (iii) one-third per year beginning on the first anniversary of the date of grant. 

The Company’s CSR activity in 2017 is as follows (in millions, except number of CSRs and grant price): 

Outstanding at December 31, 2016

Granted
Exercised
Canceled

Outstanding at December 31, 2017

  Number of CSRs  

Weighted
Average
Grant Price

479,176    $
15,227     
(117,813)    
(39,475)    
337,115    $

52.42    $
78.21     
50.26     
56.52     
53.87    $

Aggregate

Intrinsic Value  
11 

15  

As of December 31, 2017, 2016 and 2015, the weighted average fair value per share of the CSRs granted was $52.53, $34.25 

and $29.79, respectively. The Company paid approximately $4 million, $2 million and $1 million to settle exercised CSRs in 2017, 
2016 and 2015, respectively. 

The weighted average remaining contractual life of the CSRs outstanding and exercisable as of December 31, 2017 is 6.5 years 

and 5.9 years, respectively. The total aggregate intrinsic value of the exercisable CSRs and the CSRs expected to vest as of 
December 31, 2017 was approximately $15 million. 

Restricted Stock Units – Stock Settled

The Company’s RSUs will settle in shares of the Company’s common stock within 45 days of the applicable vesting date. 

RSUs granted to employees vest either (i) 25% per year beginning on the first anniversary of the date of grant; (ii) one-third per year 
beginning on the first anniversary of the grant date; (iii) 33% on the third anniversary of the date of grant and 67% on the fourth 
anniversary of the date of grant or (iv) 100% at the end of the three-year period following the grant date. Members of the Company’s 
board of directors receive RSUs that are fully vested when granted.  

119

 
 
 
 
 
 
   
   
  
   
  
   
  
   
 
 
 
 
   
   
  
   
  
   
  
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

The Company’s RSU activity in 2017 is as follows: 

Outstanding at December 31, 2016

Granted
Vested
Canceled

Outstanding at December 31, 2017

  Number of RSUs

Weighted
Average Grant-Date
Fair Value

1,720,817    $
57,699   
(563,435)  
(117,373)  
1,097,708    $

74.40 
97.03 
72.90 
71.11 
76.71  

As of December 31, 2017, there are 1.1 million RSUs outstanding with an intrinsic value of approximately $107 million. 

Restricted Stock Units – Cash Settled 

The Company’s cash settled RSUs (“Cash RSUs”) require the Company to settle in cash an amount equal to the fair value of 
the Company’s common stock on the vest date multiplied by the number of vested Cash RSUs. These awards vest 100% at the end of 
the three-year period following the date of grant. 

The Company’s Cash RSU activity in 2017 is as follows: 

Outstanding at December 31, 2016

Granted

Outstanding at December 31, 2017

Number of
Cash RSUs

Weighted
Average Grant-Date
Fair Value

—    $

9,015   
9,015    $

— 
95.98 
95.98  

As of December 31, 2017, there are 9,015 Cash RSUs outstanding with an intrinsic value of approximately $0.9 million. 

Restricted Stock Awards 

Restricted stock awards (“RSAs”) vest either (i) in equal increments of 50% on each of the second and fourth anniversaries of 

the grant date; (ii) one-third per year beginning on the first anniversary of the date of grant; or (iii) 25% on each of the second and 
third anniversaries of the grant date and 50% on the fourth anniversary of the date of grant. 

The Company’s RSA activity in 2017 is as follows: 

Outstanding at December 31, 2016

Granted
Vested

Outstanding at December 31, 2017

  Number of RSAs

Weighted
Average Grant-Date
Fair Value

367,053    $
254,582   
(181,484)  
440,151    $

80.20 
78.21 
80.20 
79.05  

As of December 31, 2017, there are 440,151 RSAs outstanding with an intrinsic value of approximately $43 million.

120

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

Performance Awards

The Company awarded performance awards that contain both service and performance based vesting criteria. Vesting occurs if 
the recipient remains employed and depends on the degree to which the Company achieves certain compound annual EPS growth and 
relative TSR goals during a three-year performance period (as defined in the award agreements). 

The Company’s performance award activity in 2017 is as follows: 

Outstanding at December 31, 2016

Granted
Canceled

Outstanding at December 31, 2017

Number of 
Performance 
Awards

Weighted
Average Grant-Date
Fair Value

—    $

519,206   
(42,874)  
476,332    $

— 
85.76 
84.90 
85.84  

As of December 31, 2017, there are 476,332 performance awards outstanding with an intrinsic value of approximately $47 

million. 

Employee Stock Purchase Plan 

Prior to December 31, 2016, the Company sponsored an Employee Stock Purchase Plan (“ESPP”) that allowed eligible 

employees to authorize payroll deductions of up to 10% of their base salary to be applied toward the purchase of full shares of the 
Company’s common stock on the last day of the offering period. During 2016 and 2015, the Company issued 0.1 million shares of 
common stock for purchases under the ESPP. Effective as of December 31, 2016, the ESPP was discontinued and participant 
contributions under the ESPP ceased. The final purchase of shares under the ESPP occurred on December 31, 2016. 

Other 

The Company sponsors a supplemental non-qualified deferred compensation plan, covering certain management employees, 

and maintains other statutory indemnity plans as required by local laws or regulations. 

20. Related Party Transactions 

During 2017, 2016 and 2015, the Company entered into a number of contracts with HUYA Bioscience International, LLC, 

primarily in Asia, in which the Company will provide up to approximately $5 million, $(8 million) net cancellations and $32 million, 
respectively, of services on a fee for services basis at arm’s length and at market rates. In 2017, 2016 and 2015, the Company 
recognized revenue of approximately $8 million, $6 million and $7 million, respectively, for services under these agreements. 

The Company has entered into other transactions with related parties including investments in and advances to unconsolidated 

affiliates that are discussed in Note 4. 

121

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

21. Operations by Geographic Location 

The table below presents the Company’s operations by geographical location. The Company attributes revenues to 

geographical locations based upon where the services are performed. The Company’s operations within each geographical region are 
further broken down to show each country that accounts for 10% or more of the totals (in millions): 

Revenues:
Americas:

United States
Other

Americas

Europe and Africa:
United Kingdom
Other

Europe and Africa

Asia-Pacific:
Japan
Other
Asia-Pacific
Revenues
Reimbursed expenses
Total revenues

(in millions)
Property, equipment and software, net:
Americas:

United States
Other

Americas

Europe and Africa:
United Kingdom
Other

Europe and Africa

Asia-Pacific:
Japan
Other

Asia-Pacific

Total property, equipment and software, net

2017

Year Ended December 31,
2016

2015

  $

  $

3,282    $
325     
3,607     

586     
2,532     
3,118     

763     
572     
1,335     
8,060     
1,679     
9,739    $

2,145    $
233     
2,378     

461     
1,594     
2,055     

587     
344     
931     
5,364     
1,514     
6,878    $

As of December 31,

2017

2016

  $

  $

623    $
27   
650   

51   
208   
259   

39   
37   
76   
985    $

1,788 
185 
1,973 

410 
1,237 
1,647 

443 
263 
706 
4,326 
1,411 
5,737  

430 
25 
455 

40 
214 
254 

36 
34 
70 
779  

122

 
 
 
 
 
 
 
 
 
 
   
      
      
  
   
      
      
  
   
   
   
      
      
  
   
   
   
   
      
      
  
   
   
   
   
   
 
 
 
 
   
 
 
 
    
 
  
 
 
    
 
  
 
 
 
 
 
 
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

22. Segments 

The following table presents the Company’s operations by reportable segment. The Company is managed through three 

reportable segments, Commercial Solutions, Research & Development Solutions and Integrated Engagement Services. Commercial 
Solutions provides mission critical information, technology solutions and real-world insights and services to the Company’s life 
science clients. Research & Development Solutions, which primarily serves biopharmaceutical clients, is engaged in research and 
development and provides clinical research and clinical trial services. Integrated Engagement Services provides contract sales to both 
biopharmaceutical clients and the broader healthcare market. Prior period segment results have been recast to conform to immaterial 
changes to management reporting in 2017. The recast only impacts the fourth quarter of 2016 as the management reporting changes 
relate to IMS Health and these results are only reflected in our results since the date of the Merger on October 3, 2016.  

Certain costs are not allocated to the Company’s segments and are reported as general corporate and unallocated expenses. 

These costs primarily consist of stock-based compensation and expenses for corporate overhead functions such as senior leadership, 
finance, human resources, information technology, facilities and legal. The Company does not allocate depreciation and amortization, 
restructuring costs, merger related costs or impairment charges to its segments. Revenues and costs for reimbursed expenses are not 
allocated to the Company’s segments. Asset information by segment is not presented, as this measure is not used by the chief 
operating decision maker to assess the performance of the Company. Information presented below is in millions: 

Revenues
Commercial Solutions
Research & Development Solutions
Integrated Engagement Services

Total revenues
Costs of revenue
Commercial Solutions
Research & Development Solutions
Integrated Engagement Services

Total costs of revenue

Selling, general and administrative expenses
Commercial Solutions
Research & Development Solutions
Integrated Engagement Services
General corporate and unallocated

Total selling, general and administrative expenses

Segment profit
Commercial Solutions
Research & Development Solutions
Integrated Engagement Services

Total segment profit

General corporate and unallocated
Depreciation and amortization
Restructuring costs
Merger related costs
Impairment charges

Total income from operations

2017

Year Ended December 31,
2016

2015

  $

  $

3,630    $
3,647     
783     
8,060     

1,917     
2,068     
637     
4,622     

703     
582     
73     
247     
1,605     

1,010     
997     
73     
2,080     
(247)    
(1,011)    
(63)    
—     
(40)    
719    $

1,089    $
3,478     
797     
5,364     

641     
1,956     
639     
3,236     

214     
579     
82     
136     
1,011     

234     
943     
76     
1,253     
(136)    
(289)    
(71)    
(87)    
(28)    
642    $

323 
3,159 
844 
4,326 

239 
1,779 
687 
2,705 

65 
556 
79 
115 
815 

19 
824 
78 
921 
(115)
(128)
(30)
— 
(2)
646  

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IQVIA HOLDINGS INC. AND SUBSIDIARIES
Notes to Consolidated Financial Statements - Continued 

23. Earnings Per Share 

The following table reconciles the basic to diluted weighted average shares outstanding (in millions): 

Basic weighted average common shares outstanding
Effect of dilutive stock options and share awards
Diluted weighted average common shares outstanding

2017

Year Ended December 31,
2016

2015

217.8     
4.8     
222.6     

149.1     
2.9     
152.0     

123.0 
2.6 
125.6  

The following table presents the weighted average number of outstanding stock-based awards not included in the computation 
of diluted earnings per share if they are subject to performance conditions or if the effect of including such stock-based awards in the 
computation would be anti-dilutive (in millions): 

Shares subject to performance conditions
Shares subject to anti-dilutive stock-based awards
Total shares excluded from diluted earnings per share

2017

Year Ended December 31,
2016

2015

0.4     
1.0     
1.4     

0.1     
1.1     
1.2     

0.1 
1.0 
1.1  

The vesting of performance awards is contingent upon the achievement of certain performance targets. The performance 

awards are not included in diluted earnings per share until the performance targets have been met. 

Stock-based awards will have a dilutive effect under the treasury method when the respective period’s average market value of 

the Company’s common stock exceeds the exercise proceeds. 

24. Comprehensive Income

Below is a summary of the components of AOCI (in millions): 

Balance at December 31, 2014
Other comprehensive (loss) income before
   reclassifications
Reclassification adjustments
Balance at December 31, 2015
Other comprehensive (loss) income before
   reclassifications
Reclassification adjustments
Balance at December 31, 2016
Other comprehensive income before
   reclassifications
Reclassification adjustments
Balance at December 31, 2017

Foreign
Currency
Translation    

Derivative
Instruments    

Defined
Benefit
Plans

Income
Taxes

Total

  $

(56)   $

(19)   $

(15)   $

31    $

(59)

(61)    
—     
(117)    

(506)    
—     
(623)    

406     
—     
(217)   $

(13)    
18     
(14)    

(4)    
28     
10     

5     
(1)    
14    $

—     
1     
(14)    

34     
1     
21     

8     
1     
30    $

9     
(6)    
34     

(5)    
(7)    
22     

197     
—     
219    $

(65)
13 
(111)

(481)
22 
(570)

616 
— 
46  

  $

124

 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
   
   
 
   
   
   
   
   
   
   
   
IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

Below is a summary of the (gains) losses reclassified from AOCI into the consolidated statements of income and the affected 

financial statement line item (in millions): 

Reclassification Adjustments
Derivative instruments:

Interest rate swaps and caps
Foreign exchange forward contracts
Foreign exchange forward contracts
Total before income taxes
Income tax (benefit) expense
Total net of income taxes

Defined benefit plans:

Amortization of actuarial losses
Income tax (benefit) expense
Total net of income taxes

25. Supplemental Cash Flow Information 

Affected Financial Statement
Line Item

2017

2016

2015

Year Ended December 31,

  Interest expense
  Revenues
  Other expense (income), net

  See Note 19

  $

  $

  $

  $

—    $
7     
(8)    
(1)    
—     
(1)   $

1    $
—     
1    $

6    $
19     
3     
28     
7     
21    $

1    $
—     
1    $

12 
6 
— 
18 
6 
12 

1 
— 
1  

The following table presents the Company’s supplemental cash flow information (in millions): 

Supplemental Cash Flow Information:

Interest paid
Income taxes paid, net of refunds

Non-cash Investing Activities:

Fair value of consideration transferred in connection with business
   combinations

2017

Year Ended December 31,
2016

2015

320    $
195    $

124    $
106    $

82 
121 

—    $

10,425    $

423  

  $
  $

  $

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IQVIA HOLDINGS INC. AND SUBSIDIARIES 
Notes to Consolidated Financial Statements - Continued 

26. Quarterly Financial Data (Unaudited) 

The following table summarizes the Company’s unaudited quarterly results of operations (in millions, except per share data): 

Revenues
Income from operations
Net income
Net income attributable to non-controlling interests
Net income attributable to IQVIA Holdings Inc.(1)
Basic earnings per share(2)
Diluted earnings per share(2)

Revenues
Income from operations
Net income (loss)
Net income attributable to non-controlling interests
Net income (loss) attributable to IQVIA Holdings Inc.
Basic earnings (loss) per share(2)
Diluted earnings (loss) per share(2)

2017
  First Quarter     Second Quarter     Third Quarter     Fourth Quarter  
2,161 
  $
203 
1,084 
(8)
1,076 
5.14 
5.02  

2,019    $
197     
89     
(5)    
84    $
0.39    $
0.38    $

1,969    $
151     
79     
(4)    
75    $
0.35    $
0.34    $

1,911    $
168     
76     
(2)    
74    $
0.32    $
0.31    $

  $
  $
  $

2016
  First Quarter     Second Quarter     Third Quarter     Fourth Quarter(3) 
1,953 
  $
144 
(175)
(3)
(178)
(0.74)
(0.74)

1,108    $
179     
109     
(2)    
107    $
0.89    $
0.88    $

1,136    $
168     
104     
(5)    
99    $
0.83    $
0.82    $

1,167    $
151     
92     
(5)    
87    $
0.73    $
0.71    $

  $
  $
  $

(1)  The significant increase during the fourth quarter of 2017 is due to the enactment of the Tax Act. See Note 18 for additional details. 
(2)  The sum of the quarterly per share amounts may not equal per share amounts reported for year-to-date periods. This is due to changes in the number of weighted 

average shares outstanding and the effects of rounding for each period. 

 (3)  The fourth quarter of 2016 includes the results of operations of IMS Health since the date of the Merger on October 3, 2016. 

27. Subsequent Event

On February 14, 2018, the IQVIA board authorized an increase in the post-merger share repurchase authorization by $1.5 

billion to a total of $5.0 billion, with $1.7 billion authorization remaining.

126

 
 
 
 
   
   
   
 
 
 
 
   
   
   
Item 9. Changes in and Disagreements with Accountants on Accounting and Financial Disclosure 

None. 

Item 9A. Controls and Procedures 

Evaluation of Disclosure Controls and Procedures 

As required by Rule 13a-15 under the Exchange Act, as amended, we carried out an evaluation of the effectiveness of the 

design and operation of our disclosure controls and procedures under the supervision and with the participation of our management, 
including the Chief Executive Officer (“CEO”) and Chief Financial Officer (“CFO”). There are inherent limitations to the 
effectiveness of any system of disclosure controls and procedures, including the possibility of human error and the circumvention or 
overriding of the controls and procedures. Accordingly, even effective disclosure controls and procedures can only provide reasonable 
assurance of achieving their control objectives. Based upon our evaluation, our CEO and CFO concluded that our disclosure controls 
and procedures were effective to provide reasonable assurance that information required to be disclosed by us in the reports that we 
file or submit under the Exchange Act, as amended, is recorded, processed, summarized and reported within the time periods specified 
in the applicable rules and forms, and that it is accumulated and communicated to our management, including our CEO and CFO, as 
appropriate, to allow timely decisions regarding required disclosure. 

Management’s Report on Internal Control over Financial Reporting 

Our management’s report on internal control over financial reporting is set forth in Part II, Item 8 of this Annual Report on 

Form 10-K and is incorporated herein by reference. 

Changes in Internal Control over Financial Reporting 

There were no changes in our internal control over financial reporting during the quarter ended December 31, 2017 that 

materially affected, or are reasonably likely to materially affect, our internal control over financial reporting. 

Item 9B. Other Information 

None. 

127

Item 10. Directors, Executive Officers and Corporate Governance 

PART III

Information required by this Item, other than the information regarding the executive officers of the Company set forth below, 
is incorporated by reference to the sections of our definitive Proxy Statement for our 2018 Annual Meeting of Stockholders (the “2018 
Proxy Statement”) entitled “Proposal No. 1:  Election of Directors,” “Security Ownership of Certain Beneficial Owners and 
Management—Section 16(a) Beneficial Ownership Reporting Compliance,” “The Company’s Corporate Governance—Documents 
Establishing our Corporate Governance” and “The Company’s Corporate Governance—Committees of the Board.”  

The current executive officers of the Company are as follows:

Name

Ari Bousbib
Michael R. McDonnell
W. Richard Staub, III
Kevin C. Knightly
James H. Erlinger III

    Age     
56
54
55
57
59

Position

Chairman, Chief Executive Officer, and President
Executive Vice President and Chief Financial Officer
President, Research & Development Solutions
President, Information & Technology Solutions
Executive Vice President, General Counsel and Secretary

Ari Bousbib, Director, Chairman, Chief Executive Officer and President

Mr. Bousbib is Chairman, Chief Executive Officer and President of the Company. He assumed this position in October 2016 
following the Merger of Quintiles and IMS Health. From 2010 until the Merger, Mr. Bousbib served as Chairman and CEO of IMS 
Health. Prior to joining IMS Health, Mr. Bousbib spent 14 years at United Technologies Corporation (“UTC”), an aerospace, defense 
and building systems company. From 2008 until 2010, he served as President of UTC’s Commercial Companies, with executive 
leadership responsibilities for the worldwide operations of Otis Elevator Company, Carrier Corporation, UTC Fire & Security and 
UTC Power Inc. From 2002 until 2008, Mr. Bousbib was President of Otis, and from 2000 to 2002, he served as its Chief Operating 
Officer. Prior to joining UTC, Mr. Bousbib was a partner at Booz Allen Hamilton. Mr. Bousbib currently serves on the board of 
directors of The Home Depot, Inc. and is a member of the Harvard Medical School Health Care Policy Advisory Council. He 
previously served on the board of directors of Best Buy, Inc. and was appointed by the President of the United States to serve on the 
President’s Commission on White House Fellowships. Mr. Bousbib holds a Master of Science Degree in Mathematics and Mechanical 
Engineering from the Ecole Superieure des Travaux Publics, Paris, and an M.B.A. from Columbia University.

Michael R. McDonnell, Executive Vice President and Chief Financial Officer

Mr. McDonnell has served as Senior Vice President and Chief Financial Officer since December 2015. Prior to joining the 

Company, Mr. McDonnell served as the Executive Vice President and Chief Financial Officer of Intelsat S.A., a leading global 
provider of satellite services, since July 2011 and as the Executive Vice President and Chief Financial Officer of its subsidiary, Intelsat 
Investments S.A., from November 2008 to May 2013. He previously served as Executive Vice President, Chief Operating Officer, 
Chief Financial Officer and Treasurer of MCG Capital Corporation, a publicly-held commercial finance company, from August 2006 
through October 2008, and as its Executive Vice President, Chief Financial Officer and Treasurer from September 2004 to October 
2008. Before joining MCG Capital Corporation, Mr. McDonnell served as Executive Vice President and Chief Financial Officer for 
EchoStar Communications Corporation (f/k/a DISH Network Corporation), a direct-to-home satellite television operator, from July 
2004 to August 2004 and as its Senior Vice President and Chief Financial Officer from August 2000 to July 2004. Mr. McDonnell 
spent 14 years at PricewaterhouseCoopers LLP, including four years as a partner. He also served on the board of directors of Catalyst 
Health Solutions, Inc., a pharmacy benefit management company, from 2005 to 2012. Mr. McDonnell has a Bachelor of Science 
degree in accounting from Georgetown University and is a certified public accountant.

W. Richard Staub, III, President, Research & Development Solutions

Mr. Staub has served as President, Research & Development Solutions since December 2016. Previously Mr. Staub served as 
President of Novella Clinical, a Quintiles company, since 2013. Prior to Novella’s 2013 acquisition by Quintiles, Mr. Staub served as 
both president and CEO of Novella Clinical since 2008. Before joining Novella Clinical in 2004, Mr. Staub was senior vice president 
of global business development for one of the world’s largest clinical research organizations. Mr. Staub’s career in the pharmaceutical 
industry began at Zeneca Pharmaceuticals in 1989 where he had progressive responsibilities as a medical and hospital sales 
representative, cardiovascular portfolio analyst and marketing manager. Mr. Staub has a Bachelor of Arts degree in Economics from 
the University of North Carolina at Chapel Hill.

128

 
 
 
Kevin C. Knightly, President, Information & Technology Solutions

Mr. Knightly has served as President, Information & Technology Solutions since October 2016. Previously Mr. Knightly 
served as Senior Vice President, Information Offerings at IMS Health from April 2015 to October 2016.  From January 2011 to March 
2015, Mr. Knightly served as Senior Vice President, Supplier Management at IMS Health. Prior to that, Mr. Knightly served in a 
number of senior financial, operations, marketing and general management roles for IMS Health, including as Senior Vice President, 
Pharma Business Management from 2007 until 2010. Mr. Knightly holds a B.S. in Economics and Accounting from the College of the 
Holy Cross, and an M.B.A. from New York University’s Stern Business School.

James H. Erlinger III, Executive Vice President, General Counsel and Secretary

Mr. Erlinger has served as our Executive Vice President, General Counsel since January 2013 and as our Secretary since 

February 2013. Prior to joining us, he spent over 27 years practicing corporate law at Bryan Cave, LLP, a multinational law firm. Mr. 
Erlinger focused his practice on outsourcing, healthcare, joint ventures, mergers and acquisitions, licensing and capital formation. Mr. 
Erlinger is a certified public accountant and received his Bachelor’s degree in Finance from the University of Missouri-Columbia, his 
Master of Business Administration from the University of Missouri-Columbia, College of Business and his Juris Doctor from the 
University of Missouri-Kansas City School of Law. 

Item 11. Executive Compensation 

The information required by this item is set forth under the headings “Director Compensation,” “Compensation Discussion 
and Analysis,” “Compensation Committee Report,” “Compensation of Named Executive Officers,” and “Compensation Committee 
Interlocks and Insider Participation” in the 2018 Proxy Statement and is incorporated herein by reference. 

Item 12. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters 

Information in response to this Item, other than Securities Authorized for Issuance Under Equity Compensation Plans, will be 

set forth in the section entitled “Security Ownership of Certain Beneficial Owners and Management” in the Company’s 2018 Proxy 
Statement, which information is incorporated herein by reference. 

Securities Authorized for Issuance Under Equity Compensation Plans

The following table provides certain information with respect to all of our equity compensation plans in effect as of December 

31, 2017:

Equity Compensation Plan Information

Number of Securities
to be issued Upon
Exercise of
Outstanding Options,
Warrants and Rights
(a)

Weighted Average
Exercise Price of
Outstanding Options,
Warrants and Rights
(b)

Number of Securities
Remaining Available for
Future Issuance Under
Equity Compensation Plans
(excluding securities
reflected in column (a))
(c)

8,503,068  (1) $

26,727  (2) $
$

8,529,795   

50.04  (3)

—   
50.04  (3)

13,412,549  (4)

—   
13,412,549   

Plan Category
Equity compensation plans
    approved by security holders
Equity compensation plans not
    approved by security holders
Total

(1) Consists of: (i) 7,005,402 shares of common stock issuable upon the exercise of outstanding time-based stock options and underlying outstanding time-based SARs; (ii) 
1,097,708 shares of common stock issuable in settlement of outstanding restricted stock units awarded and (ii) 399,958 shares of common stock issuable in settlement of 
outstanding performance units awarded. Excludes (i) 440,151 shares of common stock subject to outstanding awards of restricted stock and (ii) 76,374 shares of common 
stock subject to outstanding awards of performance stock.

(2)  Consists of outstanding awards issued to certain executives with supplemental pension benefits in accordance with their individual employment arrangements under the IMS 

Health DCERP.

(3)  The weighted-average exercise price includes all outstanding stock options and SARs but does not include restricted stock units, restricted stock, performance units or 

performance stock or IMS Health DCERP awards, all of which do not have an exercise price. If restricted stock units, performance units and other awards that constitute 
“rights” were included in this calculation, treating such awards as having an exercise price of $0, the weighted average exercise price of outstanding options, warrants and 
rights would be $41.23.

(4)  Consists of all securities remaining available under our equity compensation plans. All of these shares are available for delivery under stock options, SARs, restricted stock, 
restricted stock units, performance awards or other forms of equity award authorized by the plans. Does not include 2,251,704 shares that would have remained available 
under our Employee Stock Purchase Plan had it not been discontinued as of December 31, 2016.

129

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Item 13. Certain Relationships and Related Transactions and Director Independence 

The information required by this item is set forth under the headings “The Company’s Corporate Governance,” and “Certain 

Relationships and Related Party Transactions” in the 2018 Proxy Statement and is incorporated herein by reference. 

Item 14. Principal Accountant Fees and Services 

The information required by this item is set forth under the headings “Proposal No. 2: Ratification of the Appointment of the 
Independent Registered Public Accounting Firm—Fees Paid to Independent Registered Public Accounting Firm” in the 2018 Proxy 
Statement and is incorporated herein by reference. 

130

PART IV

Item 15. Exhibits and Financial Statement Schedules 

(a) The following documents are filed as part of this report: 

(1)  Financial Statements 

The following consolidated financial statements of IQVIA Holdings Inc. and its subsidiaries, and the independent registered 

public accounting firm’s report thereon, are included in Part II, Item 8 of this report: 

Management’s Report on Internal Control over Financial Reporting
Report of Independent Registered Public Accounting Firm
Consolidated Statements of Income
Consolidated Statements of Comprehensive Income
Consolidated Balance Sheets
Consolidated Statements of Cash Flows
Consolidated Statements of Stockholders’ Equity (Deficit)
Notes to Consolidated Financial Statements

(2)  Financial Statement Schedules for the Years Ended December 31, 2017, 2016 and 2015

Schedule I—Condensed Financial Information of Registrant (Parent Company Only)
Schedule II—Valuation and Qualifying Accounts

Page
70
71
73
74
75
76
77
78

139
144

All other schedules are omitted, since the required information is not applicable or is not present in amounts sufficient to 

require submission of the schedule, or because the information required is included in the consolidated financial statements and notes 
thereto. 

(3)  Exhibits

The exhibits in the accompanying Exhibit Index preceding the signature page are filed or furnished as a part of this report and 

are incorporated herein by reference. The Company agrees to furnish to the SEC, upon request, copies of any long-term debt 
instruments that authorize an amount of securities constituting 10% or less of the total assets of IQVIA Holdings Inc. and its 
subsidiaries on a consolidated basis. 

131

 
 
 
EXHIBIT INDEX

Exhibit
Number

2.1*

Exhibit Description

Agreement and Plan of Merger, dated as of May 3, 2016, by and between Quintiles 
Transnational Holdings Inc. and IMS Health Holdings, Inc. (which includes the Plan 
of Conversion dated as of May 3, 2016 as Exhibit A thereto).

Incorporated by Reference 

Filed
Herewith

Form

File No.

Exhibit

Filing Date

8-K

001-35907

2.1

May 3, 2016

3.1

3.2

4.1

4.2

4.3

4.4

4.5

4.6

4.7

4.8

4.9

10.1

10.2

10.3

10.4

10.5

10.6

Amended and Restated Certificate of Incorporation of IQVIA Holdings Inc., 
effective November 6, 2017 (as amended through November 6, 2017).

X

Amended and Restated Bylaws of IQVIA Holdings Inc., effective November 6, 
2017

Specimen Common Stock Certificate of Quintiles Transnational Holdings Inc.

Indenture dated as of May 12, 2015, among Quintiles Transnational Corp., the 
subsidiary guarantors listed therein and U.S. Bank National Association as trustee.

Form of 4.875% Rule 144A Senior Note due 2023 (incorporated by reference to 
Exhibit A to Exhibit 4.1 filed May 13, 2015).

Form of 4.875% Regulation S Senior Note due 2023 (incorporated by reference to 
Exhibit A to Exhibit 4.1 filed May 13, 2015).

Indenture, dated as of September 28, 2016, among Quintiles IMS Incorporated, the 
Guarantors listed therein and U.S. Bank National Association, as Trustee.

Senior Note Indenture, dated as of October 24, 2012, among IMS Health 
Incorporated, as Issuer, the Guarantors party thereto, and Wells Fargo Bank, 
National Association, as Trustee.

Senior Note Indenture, dated as of March 30, 2015, among IMS Health 
Incorporated, as Issuer, the Guarantors party thereto, and Deutsche Trustee 
Company Limited, as Trustee.

Indenture, dated February 28, 2017, among Quintiles IMS Incorporated, as Issuer, 
U.S. Bank National Association, as trustee of the Notes, and certain subsidiaries of 
the Issuer as guarantors.

Indenture, dated September 14, 2017, among Quintiles IMS Incorporated, as Issuer, 
U.S. Bank National Association, as trustee of the Notes, and certain subsidiaries of 
the Issuer as guarantors.

Fourth Amended and Restated Credit Agreement, dated as of October 3, 2016, by 
and among Quintiles IMS Incorporated, Quintiles IMS Holdings, Inc., the 
Guarantors party thereto and the Lenders party thereto (Annex B to Exhibit 10.9 
filed October 3, 2016).

Amendment No. 1, dated March 7, 2017, to Fourth Amended and Restated Credit 
Agreement, dated October 3, 2016 (and filed with the Securities and Exchange 
Commission as Annex B to Exhibit 10.9 on Form 8-K dated October 3, 2016), 
among Quintiles IMS Incorporated, Quintiles IMS Holdings, Inc., the Guarantors 
party thereto, Bank of America N.A., as Administrative Agent and Collateral Agent, 
the Incremental Term B-1 Euro Lenders party thereto and the other Lenders party 
thereto.

Amendment No. 2, dated September 18, 2017, to Fourth Amended and Restated 
Credit Agreement, by and among Quintiles IMS Incorporated, Quintiles IMS 
Holdings, Inc., the Guarantors party thereto and the Incremental Term B-2 Dollar 
Lenders party thereto.

Senior Note Purchase Agreement, dated September 14, 2016, between IMS Health 
Incorporated, a wholly owned subsidiary of IMS Health Holdings, Inc., and the 
representative of the initial purchasers named therein.

Amended and Restated Pledge and Security Agreement, dated as of March 17, 2014, 
among Healthcare Technology Intermediate Holdings, Inc., IMS Health 
Incorporated, each of the grantors party thereto, and Bank of America, N.A., as 
Administrative Agent.

U.S. Guaranty, dated as of March 17, 2014, among Healthcare Technology 
Intermediate Holdings, Inc., as Holdings, IMS Health Incorporated, as Parent 
Borrower, the other Guarantors party thereto from time to time, and Bank of 
America, N.A., as Administrative Agent.

132

8-K

001-35907

3.2

November 7, 2017

S-1/A 333-186708

8-K

001-35907

4.1

4.1

April 26, 2013

May 13, 2015

8-K

001-35907

4.2

May 13, 2015

8-K

001-35907

4.3

May 13, 2015

8-K

001-35907

4.1

October 3, 2016

333-193159

4.9

January 2, 2014

001-36381

4.1

May 15, 2015

IMS
Health
S-1

IMS
Health
10-Q

8-K

001-35907

4.1

February 28, 2017

8-K

001-35907

4.1

September 19, 2017

8-K

001-35907

10.9

October 3, 2016

8-K

001-35907

10.1

March 8, 2017

8-K

001-35907

10.1

September 19, 2017

10-Q

001-35907

10.10

November 3, 2016

333-193159

10.33

March 24, 2014

333-193159

10.34

March 24, 2014

IMS
Health
S-1/A

IMS
Health
S-1/A

 
 
 
 
 
 
 
Exhibit
Number

10.7

10.8

10.9

10.10

10.11

Exhibit Description

Incorporated by Reference 

Filed
Herewith

Form

File No.

Exhibit

Filing Date

Assignment and Assumption Agreement, dated December 10, 2009, between 
Quintiles Transnational Corp. and Quintiles Transnational Holdings Inc.

Stockholders Agreement, dated May 3, 2016, among Quintiles Transnational 
Holdings Inc. and the stockholders identified therein.

S-1

333-186708

10.12

February 15, 2013

8-K

001-35907

10.4

May 3, 2016

Voting Agreement, dated May 3, 2016, by and among Quintiles Transnational 
Holdings Inc. and affiliates of TPG Global, LLC.

8-K

001-35907

10.1

May 3, 2016

Voting Agreement, dated May 3, 2016, by and between Quintiles Transnational 
Holdings Inc. and CPP Investment Board Private Holdings Inc.

Voting Agreement, dated May 3, 2016, by and between Quintiles Transnational 
Holdings Inc. and Leonard Green & Partners, L.P.

8-K

001-35907

10.2

May 3, 2016

8-K

001-35907

10.3

May 3, 2016

   10.12

Share Repurchase Agreement, dated February 23, 2017, between Quintiles IMS 
Holdings, Inc. and the selling shareholders set forth on Schedule I thereto.

8-K

001-35907

10.1

February 24, 2017

10.13†

Form of Director Indemnification Agreement.

10.14

10.15†

Form of Indemnification Agreement with each of the non-management directors of 
Quintiles IMS Holdings Inc.

Description of Non-Employee Director Compensation, effective as of January 1, 
2017.

S-1/A 333-186708

10.13

April 19, 2013

8-K

001-35907

10.8

October 3, 2016

10-K

001-35907

10.27

February 16, 2017

10.16†

Form of Non-Competition, Non-Solicitation, Confidentiality and IP Agreement.

8-K

001-35907

10.2

October 19, 2015

10.17†

Quintiles Transnational Holdings Inc. Annual Management Incentive Plan.

S-1/A 333-186708

10.57

April 19, 2013

10.18†

Quintiles Transnational Holdings Inc. 2008 Stock Incentive Plan.

S-1

333-186708

10.17

February 15, 2013

10.19†

Form of Stock Option Award Agreement for Senior Executives under the Quintiles 
Transnational Holdings Inc. 2008 Stock Incentive Plan.

S-1

333-186708

10.18

February 15, 2013

10.20†

Form of Stock Option Award Agreement for Non-Employee Directors under the 
Quintiles Transnational Holdings Inc. 2008 Stock Incentive Plan.

S-1

333-186708

10.19

February 15, 2013

10.21†

Quintiles Transnational Holdings Inc. 2013 Stock Incentive Plan.

S-1/A 333-186708

10.22

April 19, 2013

10.22†

Form of Award Agreement Awarding Nonqualified Stock Options to Employees 
under the Quintiles Transnational Holdings Inc. 2013 Stock Incentive Plan.

S-1/A 333-186708

10.23

April 19, 2013

10.23†

Form of Award Agreement Awarding Incentive Stock Options to Employees under 
the Quintiles Transnational Holdings Inc. 2013 Stock Incentive Plan.

10-Q

001-35907

10.2

May 1, 2014

10.24†

Form of Award Agreement Awarding Nonqualified Stock Options to Non-
Employee Directors under the Quintiles Transnational Holdings Inc. 2013 Stock 
Incentive Plan.

S-1/A 333-186708

10.24

April 19, 2013

10.25†

Form of Award Agreement Awarding Stock Appreciation Rights under the Quintiles 
Transnational Holdings Inc. 2013 Stock Incentive Plan.

S-1/A 333-186708

10.56

April 19, 2013

10.26†

Form of Award Agreement Awarding Stock Appreciation Rights under the Quintiles 
IMS Holdings, Inc. 2013 Stock Incentive Plan effective February 2017.

10-K

001-35907

10.41

February 16, 2017

10.27†

Form of Award Agreement Awarding Restricted Stock Units under the Quintiles 
Transnational Holdings Inc. 2013 Stock Incentive Plan prior to February 2015.

8-K

001-35907

10.1

November 26, 2013

10.28†

Form of Award Agreement Awarding Restricted Stock Units under the Quintiles 
Transnational Holdings Inc. 2013 Stock Incentive Plan effective February 2015.

10-K

001-35907

10.34

February 12, 2015

10.29†

Form of Award Agreement Awarding Performance Units under the Quintiles 
Transnational Holdings Inc. 2013 Stock Incentive Plan.

10-K

001-35907

10.35

February 12, 2015

10.30†

Form of Award Agreement Awarding Performance Shares under the Quintiles IMS 
Holdings, Inc. 2013 Stock Incentive Plan effective February 2017.

10-K

001-35907

10.45

February 16, 2017

10.31†

Form of Restricted Stock Award Agreement under the Quintiles Transnational 
Holdings Inc. 2013 Stock Incentive Plan.

10-Q

001-35907

10.3

November 3, 2016

10.32†

Form of Award Agreement Awarding Restricted Stock Units under the Quintiles 
IMS Holdings, Inc. 2013 Stock Incentive Plan effective February 2017.

10-K

001-35907

10.47

February 16, 2017

133

 
 
 
 
 
 
 
Exhibit
Number

Exhibit Description

Incorporated by Reference 

Filed
Herewith

Form

File No.

Exhibit

Filing Date

10.33†

Quintiles IMS Holdings, Inc. Defined Contribution Executive Retirement Plan.

8-K

001-35907

10.7

October 3, 2016

10.34†

IMS Health Incorporated Defined Contribution Executive Retirement Plan, as 
amended and restated.

10.35†

First Amendment to the IMS Health Incorporated Retirement Excess Plan, dated 
March 17, 2009.

10.36†

Second Amendment to the IMS Health Incorporated Retirement Excess Plan, dated 
December 8, 2009.

10.37†

Third Amendment to the IMS Health Incorporated Retirement Excess Plan, dated 
April 5, 2011.

10.38†

Fourth Amendment to the IMS Health Incorporated Retirement Excess Plan 
(effective May 3, 2016).

333-193159

10.10

January 2, 2014

333-193159

10.12

January 2, 2014

333-193159

10.13

January 2, 2014

333-193159

10.14

January 2, 2014

001-36381

10.3

July 28, 2016

IMS
Health
S-1

IMS
Health
S-1

IMS
Health
S-1

IMS
Health
S-1

IMS
Health
10-Q

10.39†

Quintiles IMS Holdings, Inc. 2010 Equity Incentive Plan.

8-K

001-35907

10.5

October 3, 2016

10.40†

Healthcare Technology Holdings, Inc. 2010 Equity Incentive Plan, as amended and 
restated.

10.41†

Form of IMS Time-and Performance-Based Stock Option Award Agreement under 
the 2010 Equity Incentive Plan.

10.42†

Form of IMS Time-Based Stock Option Award Agreement under the 2010 Equity 
Incentive Plan.

10.43†

Form of IMS Director Stock Option Award Agreement under the 2010 Equity 
Incentive Plan.

10.44†

Form of IMS Restricted Stock Unit Award Agreement under the 2010 Equity 
Incentive Plan.

10.45†

Form of IMS Director Restricted Stock Unit Award Agreement under the 2010 
Equity Incentive Plan.

10.46†

Form of IMS Rollover Stock Appreciation Right Award Agreement under the 2010 
Equity Incentive Plan.

10.47†

IMS Health Incorporated Savings Equalization Plan, as amended and restated 
effective as of January 1, 2011.

333-193159

10.16

February 13, 2014

333-193159

10.17

January 2, 2014

333-193159

10.18

January 2, 2014

333-193159

10.19

January 2, 2014

333-193159

10.20

January 2, 2014

333-193159

10.21

January 2, 2014

333-193159

10.22

January 2, 2014

333-193159

10.15

January 2, 2014

IMS
Health
S-1/A

IMS
Health
S-1

IMS
Health
S-1

IMS
Health
S-1

IMS
Health
S-1

IMS
Health
S-1

IMS
Health
S-1

IMS
Health
S-1

10.48†

Quintiles IMS Holdings, Inc. 2014 Incentive and Stock Award Plan.

8-K

001-35907

10.6

October 3, 2016

10.49†

Form of IMS Stock Appreciation Rights Agreement under the 2014 Incentive and 
Stock Award Plan.

10.50†

Form of IMS Performance Share Award Agreement under the 2014 Incentive and 
Stock Award Plan.

10.51†

2014 IMS Health Annual Incentive Plan.

001-36381

10.1

February 10, 2015

001-36381

10.2

February 10, 2015

333-193159

10.30

March 10, 2014

IMS
Health
8-K

IMS
Health
8-K

IMS
Health
S-1/A

134

 
 
 
 
 
 
Exhibit
Number

Exhibit Description

Incorporated by Reference 

Filed
Herewith

Form

File No.

Exhibit

Filing Date

10.52†

Quintiles IMS Holdings, Inc. 2017 Incentive and Stock Award Plan.

DEF 14A 001-35907 Appendix B February 22, 2017

10.53†

Form of Award Agreement Awarding Stock Appreciation Rights under the 
Quintiles IMS Holdings, Inc. 2017 Incentive and Stock Award Plan effective April 
2017.

10-Q

001-35907

10.8

May 8, 2017

10.54†

Form of Award Agreement Awarding Performance Shares under the Quintiles IMS 
Holdings, Inc. 2017 Incentive and Stock Award Plan effective April 2017.

10-Q

001-35907

10.9

May 8, 2017

10.55†

Form of Award Agreement Awarding Restricted Stock Units under the Quintiles 
IMS Holdings, Inc. 2017 Incentive and Stock Award Plan effective April 2017.

10-Q

001-35907

10.10

May 8, 2017

10.56†

Quintiles Transnational Holdings Inc. Change of Control Severance Plan, which 
covers among others our executive officers.

8-K

001-35907

10.1

November 6, 2015

10.57†

Quintiles IMS Incorporated Employee Protection Plan, effective January 1, 2017.

10-K

001-35907

10.69

February 16, 2017

10.58†

Quintiles IMS Incorporated Savings Equalization Plan, effective December 31, 
2016.

10-K

001-35907

10.76

February 16, 2017

10.59†

Quintiles Transnational Corp. Elective Deferred Compensation Plan, as amended 
and restated.

10-Q

001-35907

10.1

October 28, 2015

10.60†

Quintiles IMS Holdings Inc. Non-Employee Director Deferral Plan, effective 
January 1, 2017.

10-K

001-35907

10.78

February 16, 2017

10.61†

Amended and Restated Employment Agreement among IMS Health Holdings, Inc., 
IMS Health Incorporated and Ari Bousbib, dated February 12, 2014.

10.62†

Senior Management Nonstatutory Option Agreement between Healthcare 
Technology Holdings, Inc. and Ari Bousbib, dated December 1, 2010.

10.63†

Senior Management Nonstatutory Option Agreement between Healthcare 
Technology Holdings, Inc. and Ari Bousbib, dated December 1, 2010.

10.64†

Restricted Stock Unit Award Agreement between IMS Health Holdings, Inc. and 
Ari Bousbib dated February 12, 2014, incorporated herein by reference to 
Amendment 2 to the Company’s Registration Statement on Form S-1 filed with the 
SEC on March 10, 2014.

10.65†

Amendment No. 1, dated December 31, 2015, to Restricted Stock Unit Award 
Agreement between IMS Health Holdings, Inc. and Ari Bousbib dated February 12, 
2014.

10.66†

Stock Appreciation Rights Agreement between IMS Health Holdings, Inc. and Ari 
Bousbib, dated February 10, 2015.

10.67†

Amendment No. 1, dated December 31, 2015, to Stock Appreciation Rights 
Agreement between IMS Health Holdings, Inc. and Ari Bousbib dated February 10, 
2015.

10.68†

Restricted Stock Award Agreement between IMS Health Holdings, Inc. and Ari 
Bousbib dated December 31, 2015.

333-193159

10.25

March 10, 2014

333-193159

10.23

February 13, 2014

333-193159

10.24

February 13, 2014

333-193159

10.29

March 10, 2014

001-36381

10.33

February 19, 2016

001-36381

10.34

February 19, 2016

001-36381

10.35

February 19, 2016

001-36381

10.36

February 19, 2016

IMS
Health
S-1/A

IMS
Health
S-1/A

IMS
Health
S-1/A

IMS
Health
S-1/A

IMS
Health
10-K

IMS
Health
10-K

IMS
Health
10-K

IMS
Health
10-K

10.69†

Letter Agreement, dated May 3, 2016, between Quintiles Transnational Holdings 
Inc. and Ari Bousbib.

8-K

001-35907

10.6

May 3, 2016

10.70†

Letter Agreement, dated May 3, 2016, between Quintiles Transnational Holdings 
Inc. and Dennis B. Gillings, CBE.

8-K

001-35907

10.5

May 3, 2016

10.71†

Letter Agreement, dated October 14, 2015, between Michael McDonnell and 
Quintiles Transnational Corp.

8-K

001-35907

10.3

October 19, 2015

135

 
 
 
 
 
 
Exhibit
Number

Exhibit Description

Incorporated by Reference 

Filed
Herewith

Form

File No.

Exhibit

Filing Date

10.72†

Initial Award Agreement Awarding Restricted Stock Units to Michael McDonnell 
under the Quintiles Transnational Holdings Inc. 2013 Stock Incentive Plan.

10-K

001-35907

10.29

February 11, 2016

10.73†

Letter agreement between the Company and Michael R. McDonnell effective on 
October 3, 2016.

8-K

001-35907

10.1

October 3, 2016

10.74†

Executive Employment Agreement, dated November 1, 2012, between James H. 
Erlinger III and Quintiles Transnational Corp.

10-K

001-35907

10.63

February 12, 2015

10.75†

Letter agreement between the Company and James H. Erlinger III effective on 
October 3, 2016.

8-K

001-35907

10.2

October 3, 2016

10.76†

Letter Agreement between the Company and W. Richard Staub, III, effective on 
December 1, 2016.

10-K

001-35907

10.104

February 16, 2017

21.1

23.1

31.1

31.2

32.1

32.2

101

List of Subsidiaries of IQVIA Holdings Inc.

Consent of PricewaterhouseCoopers LLP.

Certification of Chief Executive Officer, pursuant to Rule 13a-14(a)/15d-14(a), as 
adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

Certification of Executive Vice President and Chief Financial Officer, pursuant to 
Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley 
Act of 2002.

Certification of Chief Executive Officer, pursuant to 18 U.S.C. Section 1350, as 
adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

Certification of Executive Vice President and Chief Financial Officer, pursuant to 
18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley 
Act of 2002.

Interactive Data Files Pursuant to Rule 405 of Regulation S-T: (i) Consolidated 
Statements of Income, (ii) Consolidated Statements of Comprehensive Income, (iii) 
Consolidated Balance Sheets, (iv) Consolidated Statements of Cash Flows, and (v) 
Notes to Consolidated Financial Statements.

X

X

X

X

X

X

X

†

Indicates management contract or compensatory plan or arrangement. 

* The Merger Agreement and the description thereof included herein have been included to provide investors and stockholders with information regarding the terms 
of the agreement. They are not intended to provide any other factual information about Quintiles or IMS Health or their respective subsidiaries or affiliates or 
stockholders. The representations, warranties and covenants contained in the Merger Agreement were made only for purposes of the Merger Agreement as of the 
specific dates therein, were solely for the benefit of the parties to the Merger Agreement, may be subject to limitations agreed upon by the contracting parties, 
including being qualified by confidential disclosures made for the purposes of allocating contractual risk among the parties to the Merger Agreement instead of 
establishing these matters as facts, and may be subject to standards of materiality applicable to the contracting parties that differ from those applicable to investors. 
Investors should not rely on the representations, warranties and covenants or any descriptions thereof as characterizations of the actual state of facts or condition of 
the parties thereto or any of their respective subsidiaries or affiliates. Moreover, information concerning the subject matter of representations and warranties may 
change after the date of the Merger Agreement, which subsequent information may or may not be fully reflected in public disclosures by Quintiles or IMS Health. 
Accordingly, investors should read the representations and warranties in the Merger Agreement not in isolation but only in conjunction with the other information 
about Quintiles or IMS Health and their respective subsidiaries that the respective companies include in reports, statements and other filings they make with the 
United States Securities and Exchange Commission.

Item 16. Form 10-K Summary 

None.

136

 
 
 
 
 
 
Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this 

report to be signed on its behalf by the undersigned, thereunto duly authorized. 

SIGNATURES

IQVIA HOLDINGS INC.

By: /s/ Michael R. McDonnell

  Name: Michael R. McDonnell

Title: Executive Vice President and Chief 
Financial Officer

Date: February 16, 2018 

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following 

persons on behalf of the registrant in the capacities and on the dates indicated. 

Signature

/s/ Ari Bousbib

Ari Bousbib

/s/ Michael R. McDonnell

Michael R. McDonnell

/s/ Robert Parks

Robert Parks

/s/ Dr. Dennis B. Gillings, CBE

Dr. Dennis B. Gillings, CBE

/s/ John P. Connaughton

John P. Connaughton

/s/ Jonathan J. Coslet

Jonathan J. Coslet

/s/ John G. Danhakl

John G. Danhakl

/s/ Michael J. Evanisko

Michael J. Evanisko

/s/ James A. Fasano

James A. Fasano

Title

Date

February 16, 2018

February 16, 2018

February 16, 2018

February 16, 2018

February 16, 2018

February 16, 2018

February 16, 2018

February 16, 2018

February 16, 2018

Chairman, Chief Executive Officer and President; Director
(Principal Executive Officer)

Executive Vice President and Chief Financial Officer
(Principal Financial Officer)

Senior Vice President, Corporate Controller
(Principal Accounting Officer)

Director

Director

Director

Director

Director

Director

137

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Signature

/s/ Colleen A. Goggins

Colleen A. Goggins

/s/ Jack M. Greenberg

Jack M. Greenberg

/s/ John M. Leonard, M.D.

John M. Leonard, M.D.

/s/ Ronald A. Rittenmeyer

Ronald A. Rittenmeyer

/s/ Todd B. Sisitsky

Todd B. Sisitsky

Title

Director

Director

Director

Director

Director

Date

February 16, 2018

February 16, 2018

February 16, 2018

February 16, 2018

February 16, 2018

138

 
 
 
 
 
 
 
 
(2) Financial Statement Schedules 

Schedule I—Condensed Financial Information of Registrant 

IQVIA HOLDINGS INC. (PARENT COMPANY ONLY) 
CONDENSED STATEMENTS OF INCOME

(in millions)
Selling, general and administrative expenses
Merger related costs

Loss from operations

Interest income
Other expense, net

Loss before income taxes and equity in earnings of subsidiary

Income tax benefit

Income (loss) before equity in earnings of subsidiary

Equity in earnings of subsidiary

Net income

2017

Year Ended December 31,
2016

2015

  $

  $

1    $
—     
(1)    
—     
—     
(1)    
(3)    
2     
1,307     
1,309    $

—    $
21     
(21)    
—     
—     
(21)    
(4)    
(17)    
132     
115    $

1 
— 
(1)
— 
— 
(1)
(1)
— 
387 
387  

139

 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
   
IQVIA HOLDINGS INC. (PARENT COMPANY ONLY)
CONDENSED STATEMENTS OF COMPREHENSIVE INCOME

(in millions)
Net income
Comprehensive income (loss) adjustments:

Unrealized gains (losses) on derivative instruments, net of income tax
   expense (benefit) of $1, $3 and ($4)
Defined benefit plan adjustments, net of income tax expense of
   $3, $11 and $—
Foreign currency translation, net of income tax benefit of
   ($201), ($9) and ($5)
Reclassification adjustments:

Losses on derivative instruments included in net income, net of
   income tax expense of $—, $7 and $6
Amortization of actuarial losses and prior service costs included in
   net income

Comprehensive income (loss)

2017

Year Ended December 31,
2016

2015

  $

1,309    $

115    $

387 

4     

5     

(7)    

23     

607     

(497)    

(1)    

21     

  $

1     
1,925    $

1     
(344)   $

(9)

— 

(56)

12 

1 
335  

140

 
 
 
 
 
 
 
 
 
 
   
      
      
  
   
   
   
   
      
      
  
   
   
IQVIA HOLDINGS INC. (PARENT COMPANY ONLY)
CONDENSED BALANCE SHEETS

ASSETS

(in millions, except per share data)

Current assets:

Cash and cash equivalents
Income taxes receivable
Other current assets and receivables

Total current assets
Investment in subsidiary

Total assets

LIABILITIES AND STOCKHOLDERS’ EQUITY

Current liabilities:

Accounts payable
Income taxes payable

Total current liabilities
Investment in subsidiary
Payable to subsidiary

Total liabilities

Commitments and contingencies
Stockholders’ equity:

Common stock and additional paid-in capital, 400.0 shares authorized at
   December 31, 2017 and 2016, $0.01 par value, 249.5 and 248.3 shares
   issued and outstanding at December 31, 2017 and 2016, respectively
Accumulated deficit
Treasury stock, at cost, 41.4 and 12.9 shares at December 31, 2017 and 2016,
   respectively
Accumulated other comprehensive loss

Total stockholders’ equity
Total liabilities and stockholders’ equity

December 31,

2017

2016

  $

  $

  $

  $

1    $
—   
1   
2   
9,659   
9,661    $

—    $
—   
—   
1,552   
—   
1,552   

10,782   
655   

(3,374)  
46   
8,109   
9,661    $

12 
4 
— 
16 
8,631 
8,647 

— 
— 
— 
— 
14 
14 

10,602 
(399)

(1,000)
(570)
8,633 
8,647  

141

 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
 
  
 
 
    
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC. (PARENT COMPANY ONLY)
CONDENSED STATEMENTS OF CASH FLOWS

(in millions)
Operating activities:

Net income
Adjustments to reconcile net income to cash provided by operating 
activities:

Subsidiary loss

Change in operating assets and liabilities:

Accounts payable and accrued expenses
Income taxes payable and other liabilities

Net cash provided by operating activities

Investing activities:

Investment in subsidiary, net of dividends received

Net cash provided by investing activities

Financing activities:

Stock issued under employee stock purchase and option plans
Repurchase of common stock
Repurchase of stock options
Intercompany with subsidiary

Net cash used in financing activities

Effect of foreign currency exchange rate changes on cash
(Decrease) increase in cash and cash equivalents
Cash and cash equivalents at beginning of period
Cash and cash equivalents at end of period

2017

Year Ended December 31,
2016

2015

  $

1,309    $

115    $

387 

91     

91     

(3)    
4     
1,401     

1,150     
1,150     

91     
(2,620)    
—     
(31)    
(2,560)    
(2)    
(11)    
12     
1    $

—     
(5)    
201     

791     
791     

97     
(1,097)    
—     
15     
(985)    
—     
7     
5     
12    $

56 

— 
— 
443 

— 
— 

64 
(515)
— 
1 
(450)
— 
(7)
12 
5  

  $

142

 
 
 
 
 
 
 
 
 
 
   
      
      
  
   
      
      
  
   
   
      
      
  
   
   
   
   
      
      
  
   
   
   
      
      
  
   
   
   
   
   
   
   
   
IQVIA HOLDINGS INC. (PARENT COMPANY ONLY) 
NOTES TO CONDENSED FINANCIAL INFORMATION

The condensed parent company financial statements have been prepared in accordance with Rule 12-04, Schedule I of 
Regulation S-X as the restricted net assets of IQVIA Holdings Inc.’s (the “Company”) wholly-owned subsidiary, IQVIA Incorporated 
exceed 25% of the consolidated net assets of the Company. The ability of IQVIA Incorporated to pay dividends may be limited due to 
the restrictive covenants in the agreements governing its credit arrangements. 

These condensed parent company financial statements include the accounts of IQVIA Holdings Inc. on a standalone basis (the 
“Parent”) and the equity method of accounting is used to reflect ownership interest in its subsidiary. Refer to the consolidated financial 
statements and notes presented elsewhere herein for additional information and disclosures with respect to these financial statements. 

Since the Parent is part of a group that files a consolidated income tax return, in accordance with ASC 740, a portion of the 
consolidated amount of current and deferred income tax expense of the Company has been allocated to the Parent. The income tax 
benefit of $3, $4 million and $1 million in 2017, 2016 and 2015, respectively, represents the income tax benefit that will be or were 
already utilized in the Company’s consolidated United States federal and state income tax returns. If the Parent was not part of these 
consolidated income tax returns, it would not be able to recognize any income tax benefit, as it generates no revenue against which the 
losses could be used on a separate filer basis. 

Below is a summary of the dividends paid to the Parent by IQVIA Incorporated in 2017, 2016 and 2015 (in millions): 

Paid in December 2017
Paid in November 2017
Paid in September 2017
Paid in August 2017
Paid in May 2017
Paid in March 2017
Paid in February 2017
Paid in January 2017
Total paid in 2017
Paid in December 2016
Paid in November 2016
Paid in June 2016

Total paid in 2016
Paid in December 2015
Paid in November 2015
Paid in May 2015

Total paid in 2015

Amount

  $

  $
  $

  $
  $

  $

22 
362 
373 
168 
356 
1,237 
45 
3 
2,566 
503 
422 
89 
1,014 
1 
223 
220 
444  

143

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Schedule II—Valuation and Qualifying Accounts 

Deferred Tax Asset Valuation Allowance

Information presented below is in millions: 

December 31, 2017
December 31, 2016
December 31, 2015

(a) Recorded through purchase accounting transaction. 
(b)

Impact of reductions recorded to expense and translation adjustments. 

Additions

Balance at
Beginning
of Year

Charged to
Expenses

Charged to
Other
Accounts(a)

  Deductions(b)  

Balance at
End of
Year

  $
  $
  $

153    $
22    $
25    $

52    $
10    $
2    $

—    $
129    $
—    $

(5)   $
(8)   $
(5)   $

200 
153 
22  

144

 
 
 
   
 
 
 
 
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
IQVIA HOLDINGS INC.

Exhibit 3.1

AMENDED AND RESTATED CERTIFICATE OF INCORPORATION

1. The name of the corporation is “IQVIA Holdings Inc.” (hereinafter referred to as the “Corporation”).

2. The street address and county of the registered office of the Corporation in the State of Delaware is 1209 Orange Street, in the City of 

Wilmington, County of New Castle, 19801, and the name of its registered agent at such address is The Corporation Trust Company.

3. The purpose for which the Corporation is organized is to engage in any lawful act or activity for which corporations may be organized 

under the General Corporation Law of the State of Delaware (the “DGCL”).

4. Capitalization.

A. Authorized Shares. The Corporation shall have authority to issue four hundred and one million (401,000,000) shares, consisting 

of (a) four hundred million (400,000,000) shares of Common Stock, par value $0.01 per share (the “Common Stock”); and (b) one 
million (1,000,000) shares of Preferred Stock, par value $0.01 per share (the “Preferred Stock”).

B. Common Stock. All shares of Common Stock will be identical in all respects and will entitle the holders thereof to the same 

preferences, limitations and relative rights.

1. Voting Rights. On all matters to be voted on by the Corporation’s stockholders, each holder of record of shares of Common 

Stock will be entitled to one vote per share so held.

2. Dividends. When and as dividends are declared or paid on shares of Common Stock, whether in cash, property or securities 

of the Corporation, each holder of record of shares of Common Stock will be entitled to a ratable portion of such dividend, based 
upon the number of shares of Common Stock then held of record by each such holder.

3. Liquidation. The holders of the Common Stock will be entitled to share ratably, on the basis of the number of shares of 

Common Stock then held by each such holder, in all distributions to the holders of the Common Stock in any liquidation, 
dissolution or winding up of the Corporation.

 
 
 
 
C. Preferred Stock. The Preferred Stock may be issued from time to time in one or more series, the shares of each such series to 

have such designations, preferences, relative rights and powers, including voting powers (or qualifications, limitations or restrictions 
thereof) as are stated in the resolution or resolutions providing for the issuance of such series adopted by the Board of Directors of the 
Corporation. Authority is expressly granted to the Board of Directors, subject to the provisions hereof and to any limitations provided 
under the DGCL, to authorize the issuance of one or more series within the class of Preferred Stock, and with respect to each such series 
to determine and fix by resolution or resolutions the designations, preferences, relative rights and powers, including voting powers, full or 
limited, or no voting power, of such shares, or the qualifications, limitations or restrictions of such shares. This paragraph is intended to 
afford to the Board of Directors the maximum authority permitted under the DGCL.

5. Stockholders of the Corporation may not take any action by written consent in lieu of a meeting.

Subject to the requirements of applicable law, a special meeting of the stockholders of the Corporation may be called at any time 

(i) by a majority of the members of the Board of Directors or (ii) by the Chairman of the Board or Chief Executive Officer of the Corporation. 
Any special meeting of the stockholders shall be held on such date, at such time and at such place within or outside the State of Delaware as the 
Corporation may designate. Notice of every special meeting of the stockholders of the Corporation shall state the purpose or purposes of such 
meeting. No business may be transacted and no corporate action may be taken at a special meeting other than business within the purpose or 
purposes stated in the notice of the meeting unless all of the stockholders are present in person or by proxy, in which case any and all business 
may be transacted at the meeting even though the meeting is held without notice.

6. The Corporation shall be entitled to treat the person in whose name any shares are registered as the owner thereof for all purposes and 

shall not be bound to recognize any equitable or other claim to, or interest in, such shares on the part of any other person, whether or not the 
Corporation shall have notice thereof, except as required by applicable law.

7. The business and affairs of the Corporation shall be managed by or under the direction of the Board of Directors. The number of 
directors which shall constitute the Board of Directors shall be not less than five (5) nor more than seventeen (17), and shall be fixed in such a 
manner as may be prescribed by the Bylaws. The directors shall be divided into three classes designated Class I, Class II and Class III with 
each class consisting, as nearly as possible, of one-third of the total number of directors constituting the entire Board of Directors. Class I 
directors shall initially serve for a term expiring at the first annual meeting of stockholders following the effectiveness of this Certificate of 
Incorporation, Class II directors shall initially serve for a term expiring at the second annual meeting of stockholders following the 
effectiveness of this Certificate of Incorporation and Class III directors shall initially serve for a term expiring at the third annual meeting of 
stockholders following the effectiveness of this Certificate of Incorporation. At each succeeding annual meeting, successors to the class of 
directors whose term expires at that annual meeting shall be elected for a term expiring at the third succeeding annual meeting of stockholders. 
If the number of directors is changed, any increase or decrease shall be apportioned among the classes so as to maintain the number of directors 
in each class as nearly equal as

2

 
possible, and any additional director of any class appointed or elected to fill a newly created directorship resulting from an increase in such 
class shall hold office for a term that shall coincide with the remaining term of that class, but in no case shall a decrease in the number of 
directors remove or shorten the term of any incumbent director. A director shall hold office until the annual meeting at which his or her term 
expires and until his or her successor shall be elected and qualified, subject, however, to prior death, resignation, retirement, disqualification or 
removal from office. The Board of Directors is authorized to assign members of the Board of Directors already in office to their respective 
initial class.

8. In furtherance and not in limitation of the powers conferred by law, the Board of Directors is expressly authorized to adopt, alter, 
amend and repeal the Bylaws of the Corporation. Any amendment, alteration, change, addition or repeal of the Bylaws of the Corporation by 
the stockholders of the Corporation shall require the affirmative vote of the holders of at least seventy-five percent (75%) of the outstanding 
shares of the Corporation, voting together as a class, entitled to vote on such amendment, alteration, change, addition or repeal.

9. Subject to the Bylaws of the Corporation, the stockholders may, at any meeting the notice of which shall state that it is called for that 

purpose, remove, only for cause and with the affirmative vote of the holders of at least seventy-five percent (75%) of the outstanding shares of 
the Corporation, voting together as a class, any Director, or the entire Board of Directors, and fill the vacancy or vacancies; in each case 
provided that whenever any director shall have been elected by a voting group of stockholders, only the stockholders from that voting group 
may participate in the vote to remove him or her, and such vacancy may be filled only by the holders of shares of that voting group. Subject to 
the Bylaws of the Corporation, vacancies caused by any such removal and not filled by the stockholders at the meeting at which such removal 
shall have been made, or any vacancy caused by the death or resignation of any director or for any other reason, and any newly created 
directorship resulting from any increase in the authorized number of Directors, may be filled only by the affirmative vote of a majority of the 
directors then in office, although less than a quorum. Any director so elected to fill any such vacancy or newly created directorship shall hold 
office until the next election of the class for which such director has been chosen and until his or her successor is elected and qualified or until 
his or her earlier resignation or removal.

Subject to the Bylaws of the Corporation, when one or more directors shall resign effective at a future date, a majority of the 

directors then in office, including those who have so resigned, shall have power to fill such vacancy or vacancies, the vote thereon to take effect 
when such resignation or resignations shall become effective, and each director so chosen shall hold office as herein provided in connection 
with the filling of other vacancies.

10. Limitation of Director Liability; Indemnification

(A) Limitation of Director Liability. To the fullest extent that the DGCL or any other law of the State of Delaware (as they exist 

on the date hereof or as they may hereafter be amended) permits the limitation or elimination of the liability of directors, no director of the 
Corporation shall be liable to the Corporation or its stockholders for monetary damages for breach of fiduciary duty as a director. No 
amendment to, or modification or repeal of, this Article 10 shall adversely affect any right or protection of a director of the Corporation 
existing

3

 
hereunder with respect to any state of facts existing or act or omission occurring, or any cause of action, suit or claim that, but for this Article 
10, would accrue or arise, prior to such amendment, modification or repeal. If the DGCL is amended after the Effective Time to authorize 
corporate action further eliminating or limiting the personal liability of directors, then the liability of a director of the Corporation shall be 
eliminated or limited to the fullest extent permitted by the DGCL, as so amended.

(B) Indemnification.

1. Nature of Indemnity. The Corporation shall indemnify any person (an “Indemnitee”) who at any time serves or has served 

as a director or officer of the Corporation, or at the request of the Corporation is or was serving as a director, officer, partner, 
member, trustee, employee or agent of any other foreign or domestic corporation, partnership, limited liability company, joint 
venture, trust, employee benefit plan, or other enterprise, or as a trustee or administrator under any employee benefit plan of the 
Corporation or any wholly owned subsidiary thereof (any such entity, an “Other Entity”), to the fullest extent from time to time 
permitted by law in the event he or she is or is threatened to be involved as a party, witness or otherwise in any threatened, pending 
or completed action, demand, suit or proceeding, whether civil, criminal, administrative, arbitrative, investigative or other and 
whether formal or informal, including but not limited to any investigation, inquiry, hearing or alternative dispute resolution process, 
whether or not brought by or on behalf of the Corporation, by reason of the fact that he or she is or was acting in such capacity; 
provided , however , that the Corporation shall not indemnify any such Indemnitee against liability or expenses such person may 
incur on account of his or her activities which were, at the time taken, known or believed by him or her to be clearly in conflict with 
the best interests of the Corporation. The rights of those receiving indemnification hereunder shall, to the fullest extent from time to 
time permitted by law, cover (1) reasonable expenses, including without limitation all reasonable attorneys’ fees actually incurred 
by him or her in connection with any such action, suit or proceeding; (2) all payments made by him or her in satisfaction of any 
judgment, money decree, fine (including an excise tax assessed with respect to an employee benefit plan), penalty, or settlement for 
which he or she may have become liable in such action, suit or proceeding; and (3) all reasonable expenses incurred in enforcing the 
indemnification rights provided herein. The rights granted herein shall not be limited by the provisions contained in Section 145 of 
the DGCL.

2. Determination That Indemnification Is Proper. The Board of Directors shall take all such action as may be necessary and 

appropriate to authorize the Corporation to pay the indemnification required by Article 10(B)(1), including without limitation 
making a determination that indemnification is permissible in the circumstances and a good faith evaluation of the manner in which 
the claimant for indemnity acted and of the reasonable amount of indemnity due him or her. The Board of Directors may appoint a 
committee or special counsel to make such determination and evaluation. The Board of Directors may give notice to, and obtain 
approval by, the stockholders of the Corporation for any decision to indemnify.

4

 
3. Advance Payment of Expenses. Expenses incurred by a director or an officer in connection with an action, suit or 

proceeding referred to in Article 10(B)(1) shall be paid by the Corporation in advance of the final disposition of such action, suit or 
proceeding upon receipt of an undertaking by or on behalf of the director or officer to repay such amount unless it shall ultimately 
be determined that he or she is entitled to be indemnified by the Corporation pursuant to this Article 10(B); provided , however , 
that the Corporation shall have no obligation to advance expenses incurred by a director or officer with respect to any claim 
initiated by such director or officer without the prior written consent of or authorization of the Board of Directors (other than a 
claim brought by a director or officer to enforce his or her or rights under this Article 10). Such expenses incurred by other 
employees and agents may be so paid upon such terms and conditions, if any, as the Board of Directors deems appropriate. The 
Board of Directors may authorize the Corporation’s legal counsel to represent such director, officer, employee or agent in any 
action, suit or proceeding, whether or not the Corporation is a party to such action, suit or proceeding.

4. No Duplication of Payments. The Corporation shall not be liable under this Article 10(B) to make any payment in 
connection with any claim made against any Indemnitee to the extent such person has otherwise received payment (under any 
insurance policy, bylaw or otherwise) of the amounts otherwise payable as indemnity hereunder; provided , however , that the 
Corporation agrees that, as between the Corporation, on the one hand, and any Sponsor Stockholder with whom a director is or was 
affiliated and any insurer providing insurance coverage to such Sponsor Stockholder, on the other hand, the Corporation (1) is the 
indemnitor of first resort under this Article 10 (i.e., its obligations under this Article 10 are primary and any indemnification or 
advancement obligations of any Sponsor Stockholder with whom a director is or was affiliated and the obligations of any insurer of 
such Sponsor Stockholder to provide insurance coverage with respect to the same obligations are secondary), (2) shall be required 
to advance the full amount of expenses incurred by the director and shall be liable for the full amount of indemnification obligations 
as required by the terms of this Certificate of Incorporation and any other agreements the Corporation may have with the director, 
without regard to any rights the director may have against such Sponsor Stockholder, and (c) unconditionally and irrevocably 
waives, relinquishes, releases such Sponsor Stockholder from and agrees not to exercise any rights that it may have with respect to 
any and all claims for contribution, subrogation or any other recovery of any kind in respect thereof. For purposes of this Article 10, 
“Sponsor Stockholder” means any current or former stockholder that is or was party to the Stockholders Agreement (as defined 
below), any Affiliate (as defined in the Stockholders Agreement) of such stockholder (other than the Corporation and its 
subsidiaries), and/or any other investment entity or related management company that is advised by the same investment adviser as 
any of the foregoing entities or by an Affiliate (as defined in the Stockholders Agreement) of such investment adviser.

5. Subrogation. Subject to the limitations set forth in Article 10(B)(4), in the event of payment of indemnification to an 
Indemnitee, the Corporation shall be subrogated to the extent of such payment to any right of recovery such person may have and 
such

5

 
person, as a condition of receiving indemnification from the Corporation, shall execute all documents and do all things that the 
Corporation may deem necessary or desirable to perfect such right of recovery, including the execution of such documents 
necessary to enable the Corporation effectively to enforce any such recovery.

(C) Insurance. The Corporation shall have the power to purchase and maintain insurance on behalf of any person who is or was a 
director, officer, trustee, employee, member or agent of the Corporation, or was serving at the request of the Corporation as a director, officer, 
trustee, employee, member or agent of an Other Entity, against any liability asserted against the person and incurred by the person in any such 
capacity, or arising out of his or her status as such, whether or not the Corporation would have the power or the obligation to indemnify such 
person against such liability under the provisions of this Article 10 or the DGCL.

(D) Non-Exclusivity of Rights. The rights conferred on any Indemnitee by this Article 10 are not exclusive of other rights arising 
under any bylaw, agreement, vote of directors or stockholders or otherwise, and shall continue as to a person who has ceased to be a director, 
officer, employee or agent, and shall inure to the benefit of the heirs and legal representatives of such Indemnitee. The Corporation may enter 
into an agreement with any of its directors, officers, employees or agents providing for indemnification and advancement of expenses, 
including attorneys’ fees, that may change, enhance, qualify or limit any right to indemnification or advancement of expenses created by this 
Article 10.

(E) Survival; Amendment or Repeal. The foregoing provisions of this Article 10 shall be deemed to be a contract between the 

Corporation and each Indemnitee at any time while these provisions as well as the relevant provisions of the DGCL are in effect and any repeal 
or modification thereof shall not affect any right or obligation then existing with respect to any state of facts then or previously existing or any 
action, suit, or proceeding previously or thereafter brought or threatened based in whole or in part upon any such state of facts. Such a contract 
right may not be modified retroactively without the consent of the Indemnitee.

(F) Other Indemnification. This Article 10 shall not limit the right of the Corporation, to the extent and in the manner permitted by 

law, to indemnify and to advance expenses to Indemnitees or persons other than Indemnitees when and as authorized by appropriate corporate 
action, including without limitation by separate agreement with the Corporation.

11. Except as set forth herein, the Corporation reserves the right to amend, alter, change or repeal any provision contained in this 
Certificate of Incorporation, in the manner now or hereafter prescribed by statute, and all rights conferred on stockholders herein are granted 
subject to this reservation.

12. Meetings of stockholders may be held within or without the State of Delaware, as the Bylaws of the Corporation may provide. The 

books of the Corporation may be kept (subject to any provision contained in applicable law) outside the State of Delaware at such place as may 
be designated from time to time by the Board of Directors or in the Bylaws of the Corporation.

13. The stockholders of the Corporation shall have no right to cumulate their votes for the election of directors.

6

 
14. Renouncement of Corporate Opportunity.

A. Scope. The provisions of this Article 14 are set forth to define, to the extent permitted by applicable law, the duties of Exempted 

Persons (as defined below) to the Corporation and, to the extent applicable, its stockholders, with respect to certain classes or categories 
of business opportunities. “Exempted Person” means each of the Bain Shareholders, the TPG Shareholders, the CPP Shareholder and the 
LG Shareholders (each as defined in the Shareholders Agreement, dated as of May 3, 2016, by and among the Corporation and certain of 
its stockholders named therein, as such agreement existed as of May 3, 2016 (the “Stockholders Agreement”)), their respective Affiliates 
(other than the Corporation and its subsidiaries), TPG Global, LLC and Bain Capital, LLC and their Affiliates and all of their respective 
partners, principals, directors, officers, members, managers, managing directors and/or employees, including any of the foregoing who 
serve as officers or directors of the Corporation. Solely for purposes of this Article 14, references to “Affiliate”, “Nominee”, and 
“Stockholder Group” have the meaning ascribed to such terms in the Stockholders Agreement.

B. Competition and Allocation of Corporate Opportunities. The Exempted Persons shall not have any fiduciary or other duty to 

refrain from engaging directly or indirectly in the same or similar business activities or lines of business as the Corporation or any of its 
subsidiaries. To the fullest extent permitted by applicable law, the Corporation, on behalf of itself and its subsidiaries, renounces any 
interest or expectancy of the Corporation and its subsidiaries in, or in being offered an opportunity to participate in, business 
opportunities that are from time to time presented to the Exempted Persons, even if the opportunity is one that the Corporation or its 
subsidiaries might reasonably be deemed to have pursued or had the ability or desire to pursue if granted the opportunity to do so, and 
each such Exempted Person shall have no duty to communicate or offer such business opportunity to the Corporation and, to the fullest 
extent permitted by applicable law, shall not be liable to the Corporation or any of its subsidiaries or, to the extent applicable, any of its or 
their stockholders, for breach of any fiduciary or other duty, as a director or officer or otherwise, by reason of the fact that such Exempted 
Person pursues or acquires such business opportunity, directs such business opportunity to another person or fails to present such business 
opportunity, or information regarding such business opportunity, to the Corporation or its subsidiaries.

C. Certain Matters Deemed Not Corporate Opportunities. In addition to and notwithstanding the foregoing provisions of this 

Article 14, a corporate opportunity shall not be deemed to belong to the Corporation if it is a business opportunity that the Corporation is 
not financially able or contractually permitted or legally able to undertake, or that is, from its nature, not in the line of the Corporation’s 
business or is of no practical advantage to it or that is one in which the Corporation has no interest or reasonable expectancy.

D. Effect of Stockholders Agreement. The provisions of Sections B and C of this Article 14 (i) shall be subject to compliance with 

any procedures regarding corporate opportunities specified in the Stockholders Agreement and (ii) shall continue with respect to an 
Exempted Person until the first date that both of the following conditions are true

7

 
(a) such Exempted Person’s applicable Stockholder Group is not entitled to designate at least one (1) Nominee to the Board of Directors 
of the Corporation pursuant to the Stockholders Agreement, and (b) no individual is serving on the Board who has at any time been 
designated as a Nominee by such Exempted Person’s applicable Stockholder Group.

E. Amendment of this Article 14. No amendment or repeal of this Article 14 in accordance with the provisions of Article 11 shall 

apply to or have any effect on the liability or alleged liability of any Exempted Person for or with respect to any activities or opportunities 
of which such Exempted Person becomes aware prior to such amendment or repeal. This Article 14 shall not limit any protections or 
defenses available to, or indemnification or advancement rights of, any director or officer of the Corporation under this Certificate of 
Incorporation of the Corporation, the Corporation’s bylaws or applicable law.

8

 
IQVIA HOLDINGS INC.

SUBSIDIARIES OF THE REGISTRANT

Subsidiary
AIECO IT Solutions India Private Ltd.
Albatross Financial Solutions Limited

Alimed Egeszsegugyi Szolgaltato Kft.

Appature, Inc.

Ardentia International Limited

Aseorias IMS Health Chile Limitada

Asserta Centroamerica Medicion de Mercados, S.A.

Battaerd Mansley (Proprietary) Limited

Battaerd Mansley Pty. Ltd.

Benefit Canada, Inc.

Benefit Holding, Inc.

Bulgarian Branch (FKA Cgd CZ sro, Bulgarian Branch)

BUZZEOPDMA LLC

Cambridge Pharma Consultancy Limited

Cambridge Pharma Consultancy, Inc.

CDS - Center de Service SAS

Cegedim Venezuela C.A.

Cenduit (India) Services Private Company Limited

Cenduit Limited

Cenduit LLC

Cenduit Mauritius Holdings Company

Chemical Information Services, LLC

Clinical Financial Services, LLC

Clinical Lab Minority Shareholder Limited

Coordinated Management Holdings L.L.C.

Coordinated Management System, Inc.

CORE Center for Outcomes Research GmbH

CORE Holding GmbH

Coté Orphan Consulting UK Limited

Coté Orphan Limited

Coté Orphan, LLC

CRM Health Korea Ltd.

CSD Health Korea Ltd.

Data Niche Associates, INC.

Datadina Ecuador S.A.

Dataline Software Limited

Datec Industria e Comercio, Distribudora Grafica e Mala Direta Ltda.

Dimensiions Healthcare LLC

Exhibit 21.1

Jurisdiction or 
State of Organization
India
United Kingdom

Hungary

Washington

United Kingdom

Chile

Guatemala

South Africa

Australia

Canada

North Carolina

Bulgaria

Delaware

United Kingdom

Delaware

France

Venezuela

India

United Kingdom

Delaware

Mauritius

Texas

Pennsylvania

United Kingdom

Delaware

Delaware

Switzerland

Switzerland

United Kingdom

Ireland

Maryland

India

United Kingdom

Hungary

Washington

United Kingdom

Chile

Guatemala

Subsidiary
Drug Dev Inc.
Drugdev Limited 

EA Institute L.L.C.

Enterprise Associates, LLC

Epenicus, LLC

EPS Research Limited

EPS Software Limited

Forcea NV

Foresight Group International UK LTD

Foresight Group Japan G.K.

Foresight Group US, LLC

Foresight IT Solutions Consulting India Private Limited

Global Crown Investment Limited

Grace Data Corporation 

HighPoint Solutions, LLC

Highpoint Solutions, LLC

Hospital Marketing Services Ltd.

Hotel Lot C-8B, LLC

Iasist Holdco Limited

Iasist Potugal, Consultadoria na Área de Saúde, Unipessoal, Lda

Iasist SAU Agencia en Chile

Iasist Sociedad Anonima Unipersonal 

iGuard, Inc.

Impact RX, LLC

IMS (Gibraltar) Holding Limited 

IMS (UK) Pension Plan Trustee Company Limited

IMS AB

IMS Adriatic d.o.o. za konzalting

IMS AG (Mexico Branch)

IMS Bulgaria E.o.o.D.

IMS CHINAMETRIK LIMITED

IMS Consulting Myanmar Company, Ltd.

IMS Health - Thailand Branch

IMS Health (Australia) Partnership

IMS Health (N.Z.) Limited

IMS Health (Pty.) Ltd.

IMS Health a.s.

IMS Health Analytics Services Private Limited

IMS Health Argentina S.A.

IMS Health Asia PTE. LTD.

IMS Health Australia Holding Pty. Ltd.

IMS Health Australia Pty. Ltd.

IMS Health B.V.

IMS Health Bangladesh Limited

Jurisdiction or 
State of Organization
South Africa
Australia

Canada

North Carolina

Bulgaria

Delaware

United Kingdom

Delaware

France

Venezuela

Florida

India

Hong Kong

Nebraska

Delaware

Switzerland

United Kingdom

North Carolina

United Kingdom

Portugal

Chile

Spain

North Carolina

South Africa

Gibraltar

United Kingdom

Sweden

Croatia

Mexico

Bulgaria

Hong Kong

Myanmar

Thailand

Australia

New Zealand

South Africa

Czech Republic

India

Argentina

Singapore

Australia

Australia

Netherlands

Bangladesh

Subsidiary
IMS Health Bolivia S.R.L.
IMS Health Canada Inc.

IMS Health Capital, INC.

IMS Health Colombia S.A.

IMS Health Consulting bvba

IMS Health Cyprus LTD

IMS Health de Venezuela C.A.

IMS Health Del Peru S.A.

IMS Health Do Brasil Ltda.

IMS Health Egypt Limited

IMS Health Finance B.V.

IMS Health Group Limited

IMS Health Hellas Technology Solutions S.A.

IMS Health Holdings (Pty.) Ltd.

IMS Health II - Technology Solutions Lda.

IMS Health Informatin Solutions Australia Pty. Ltd

IMS Health Information and Consulting Services India Private Limited

IMS Health Information Solutions (China) Co. Ltd.

IMS Health Information Solutions Argentina S.A.

IMS Health Information Solutions GmbH

IMS Health Information Solutions India Private Ltd.

IMS Health Information Solutions Japan K.K.

IMS Health Korea LTD

IMS Health Lanka (Private) Limited

IMS Health Limited

IMS Health LLC

IMS Health Malaysia Sdn. Bhd.

IMS Health Marktforschung GmbH

IMS Health Networks Limited

IMS Health Operations Center Philippines, Inc.

IMS Health Pakistan (Private) Limited

IMS Health Paraguay SRL

IMS Health Philippines, Inc.

IMS Health Puerto Rico Inc.

IMS Health Regional Pte. Ltd.

IMS Health S.P.R.L.

IMS Health S.r.l.

IMS Health Services Ltd.

IMS Health Soluçoes de Tecnologia DO Brazil Ltda.

IMS Health Surveys Limited

IMS Health Taiwan LTD.

IMS Health Technology Solutions (China) Co. Ltd.

IMS Health Technology Solutions Australia Pty. Ltd

IMS Health Technology Solutions Colombia Ltda.

Jurisdiction or 
State of Organization
Bolivia
Canada

Nevada

Colombia

Belgium

Cyprus

Venezuela

Peru

Brazil

Egypt

Netherlands

United Kingdom

Greece

South Africa

Portugal

Australia

India

China

Argentina

Austria

India

Japan

Korea

Sri Lanka

Ireland

Russia

Malaysia

Austria

United Kingdom

Philippines

Pakistan

Paraguay

Philippines

Puerto Rico

Singapore

Belgium

Italy

Hungary

Brazil

United Kingdom

Taiwan

China

Australia

Colombia

Subsidiary
IMS Health Technology Solutions Czech Republic SRO
IMS Health Technology Solutions Egypt L.L.C.

IMS Health Technology Solutions Finland OY

IMS Health Technology Solutions Holdings AB

IMS Health Technology Solutions Hungary Ltd.

IMS Health Technology Solutions India Private Ltd.

IMS Health Technology Solutions Japan K.K.

IMS Health Technology Solutions Kazakhstan, LLC

IMS Health Technology Solutions LLC

IMS Health Technology Solutions Romania Srl

IMS Health Technology Solutions Slovakia SRO

IMS Health Technology Solutions Sweden AB

IMS Health Technology Solutions Ukraine LLC

IMS Health Technology Tunisia 

IMS Health Tibbi Istatistik Ticaret ve Musavirlik Ltd. Sirketi

IMS Health Tunisia sarl

IMS Health Uruguay S.A.

IMS Health, LDA.

IMS Holdings (U.K.) Limited

IMS Hospital Group Limited

IMS Informatics AG

IMS Informatics Holding AG

IMS Information Medical Statistics (Israel) LTD.

IMS Information Medical Statistics Spol.s.r.o.

IMS Information Solutions Medical Research Limited

IMS Information Solutions UK Ltd.

IMS International (Proprietary) Limited

IMS Japan K.K.

IMS Market Research Consult (Beijing)

IMS Market Research Consultins (Shanghai) Co., Ltd.

IMS Meridian Limited

IMS Meridian Research Limited

IMS Pharmaceutical Services Srl.

IMS Republica Dominicana, S.A.

IMS Services, pharmaceutical marketing services Ltd.

IMS Software Services LTD.

IMS Technology Solutions UK Limited

Infocus Health Limited

Infopharm Ltd.

Informations Medicales & Statistiques S.A.R.L.

Innovex Holdings I LLC

Innovex Merger Corp.

Innovex Saglik Hizmetleri Arastirma ve Danismanlik Ticaret Limited Sirketi

Innovex Saglik Urunleri Pazarlame ve Hizmet Danismanlik Anonim Sirketi

Jurisdiction or 
State of Organization
Czech Republic
Egypt

Finland

Sweden

Hungary

India

Japan 

Kazakhstan

Russia

Romania

Slovak Republic

Sweden

Ukraine

Tunisia

Turkey

Tunisia

Uruguay

Portugal

United Kingdom

United Kingdom

Switzerland

Switzerland

Israel

Slovak Republic

United Kingdom

United Kingdom

South Africa

Japan and Delaware

China

China

Hong Kong

British Virgin Islands

Romania

Dominican Republic

Slovenia

Delaware

United Kingdom

United Kingdom

United Kingdom

Morocco

Delaware

North Carolina

Turkey

Turkey

Subsidiary
Institute of Medical Communications NCO
Intercontinental Medical Statistics International, LTD. (DE)

Interstatistik AG

IPP Informacion Promocional y Publicitaria S.A. de C.V.

IQVIA AG

IQVIA AG (UK Branch)

IQVIA Asia Pacific Commercial Holdings LLC

IQVIA Beteiligungs-gesellschaft mbH

IQVIA BioSciences Holdings LLC

IQVIA ChinaMetrik Inc.

IQVIA Commercial Consulting Sp. z.o.o.

IQVIA Commercial Deutschland GmbH

IQVIA Commercial Finance Inc.

IQVIA Commercial GmbH & Co. OHG

IQVIA Commercial India Holdings Corp.

IQVIA Commercial Licensing Associates LLC

IQVIA Commercial Services LLC

IQVIA Commercial Software GmbH

IQVIA Commercial Sp. z.o.o.

IQVIA Commercial Trading Corp.

IQVIA Deutschland GmbH

IQVIA Government Solutions Inc.

IQVIA Holdings France SAS

IQVIA Holdings Inc. 

IQVIA IES European Holdings

IQVIA Inc. 

IQVIA Information, S.A.

IQVIA Informations Solutions France SAS 

IQVIA Ltd.

IQVIA Market Intelligence LLC

IQVIA Medical Communications & Consulting, Inc.

IQVIA Medical Radar AB

IQVIA Operations France SAS

IQVIA Partners AS

IQVIA Pharma Inc.

IQVIA Pharma Services Corp.

IQVIA Phase One Services LLC

IQVIA RDS Asia Inc

IQVIA RDS BT Inc.

IQVIA RDS Consulting Inc.

IQVIA RDS France SAS

IQVIA RDS Funding LLC

IQVIA RDS Holdings

IQVIA RDS Inc.

Jurisdiction or 
State of Organization
Russia
Delaware

Switzerland

Mexico

Switzerland

United Kingdom

North Carolina

Germany

Delaware

Delaware

Poland

Germany

Delaware

Germany

Delaware

Delaware

Delaware

Germany

Poland

Delaware

Germany

Delaware

France

Delaware

United Kingdom

Delaware

Spain

France

United Kingdom

North Carolina

New Jersey

Sweden

France

Denmark

North Carolina

North Carolina

Kansas

North Carolina

North Carolina

North Carolina

France

North Carolina

United Kingdom

North Carolina

Subsidiary
IQVIA RDS Latin America LLC
IQVIA RDS Poland Sp. Zoo

IQVIA RDS Spain S.L.

IQVIA RDS Spain S.L., Representacao. Permanente em Portugal

IQVIA RDS Support Sarl

IQVIA RDS Transfer LLC

IQVIA RDS UK Holdings Limited

IQVIA Solutions Denmark AS

IQVIA Solutions Finance UK I Limited

IQVIA Solutions Finance UK II Ltd.

IQVIA Solutions Finance UK III Ltd.

IQVIA Solutions Finance UK V. Ltd.

IQVIA Solutions Finland OY

IQVIA Solutions Global Holdings UK Ltd.

IQVIA Solutions GmbH

IQVIA Solutions HQ Limited

IQVIA Solutions Norway AS

IQVIA Solutions Sweden AB

IQVIA Solutions UK Investments Ltd.

IQVIA Solutions UK Limited

IQVIA Technology Services Ltd.

IQVIA Technology Solutions Finland OY

IQVIA Technology Solutions Poland SP. z.o.o.

IQVIA Trading Management Inc.

IQVIA Transportation Services Corp.

IQVIA World Publications Ltd.

Kun Tuo Medical Research & Development (Beijing) Co. Ltd.

Laboratorie Novex Pharma Sarl

Laboratorio Commuq Pharma SL

M&H Informatics (BD) LTD.

Mecurial Insights Holding Pty. Ltd.

Mecurial Insights Pty. Ltd.

Med-Vantage, Inc.

Mercados Y Analisis, S.A.

Meridian Research Vietnam Ltd.

MG Recherche

M-TAG Australia Pty. Ltd.

Nordisk Medicin Information AB

Novella Clinical LLC

Novella Clinical Ltd.

Novex Pharma Gmbh

Novex Pharma Laboratorio S.L.

Novex Pharma Limited

Operaciones Centralizadas Latinoamericana Limitada

Jurisdiction or 
State of Organization
North Carolina
Poland

Spain

Portugal

France

Delaware

United Kingdom

Denmark

United Kingdom

United Kingdom

United Kingdom

United Kingdom

Finland

United Kingdom

Switzerland

United Kingdom

Norway

Sweden

United Kingdom

United Kingdom

United Kingdom

Finland

Poland

Delaware

Delaware

United Kingdom

China

France

Spain

Bangladesh

Australia

Australia

Delaware

Spain

Vietnam

France

Australia

Sweden

Delaware

United Kingdom

Germany

Spain

United Kingdom

Chile

Subsidiary
Outcome Sciences LLC
Penderwood Limited

Pharma Deals Limited

Pharma Strategy Group Ltd.

Pharmadata s.r.o.

Pharmaforce, S.A. de C.V.

PharmARC Consulting Services GmbH

PharmARC Inc.

Pharm-Consult Limited Liability Partnership

Pilgrim Quality Solutions EMEA BV

Pilgrim Software Asia PVT, Ltd

Pilgrim Software Holding B.V.

Polaris Cooperatie

Polaris Management Partners LLC

Polaris Solutions BV

Polaris Solutions LLC

Polaris Solutions Ltd.

PR Editions S.A.S.

Primeum IQVIA SAS

Privacy Analytics Inc.

Professional Pharmaceutical Marketing Services (Pty.) Ltd.

PT IMS Health Indonesia

PT Quintiles Indonesia

Pygargus AB

Q Squared Solutions (Beijing) Co. Ltd.

Q Squared Solutions (India) Private Limited

Q Squared Solutions (Quest) Limited

Q Squared Solutions (Quest) LLC

Q Squared Solutions (Shanghai) Co. Ltd.

Q Squared Solutions B.V.

Q Squared Solutions BioSciences LLC

Q Squared Solutions China (Quest) Limited

Q Squared Solutions China Limited

Q Squared Solutions Expression Analysis LLC

Q Squared Solutions Holdings B.V.

Q Squared Solutions Holdings Limited

Q Squared Solutions Holdings LLC

Q Squared Solutions K.K.

Q Squared Solutions Limited

Q Squared Solutions LLC

Q Squared Solutions Proprietary Limited

Q Squared Solutions Pte. Ltd.

Q Squared Solutions S.A.

Q2 Metrics 

Jurisdiction or 
State of Organization
Delaware
United Kingdom

United Kingdom

United Kingdom

Slovak Republic

Mexico

Switzerland

New Jersey

Kazakhstan

Netherlands 

Nepal

Netherlands 

Netherlands

New Jersey

Netherlands

New York

Hong Kong

France

France

Canada

South Africa

Indonesia

Indonesia

Sweden

China

India

United Kingdom

Delaware

China

Netherlands

Delaware

United Kingdom

United Kingdom

Delaware

Netherlands

United Kingdom

Delaware

Japan

United Kingdom

North Carolina

South Africa

Singapore

Argentina

Canada

Subsidiary
Qcare Site Services, Inc.
QIMS Pharma Services SA DE CV

Quintiles (Pty.) Ltd.

Quintiles (Thailand) Co. Ltd.

Quintiles AB

Quintiles AG

Quintiles Argentina S.A.

Quintiles Austria GmbH

Quintiles B.V.

Quintiles Belgium N.V.

Quintiles Benin Ltd.

Quintiles Brasil Ltda.

Quintiles Bulgaria EOOD

Quintiles Canada, Inc.

Quintiles Chile

Quintiles Clindata (Pty.) Limited

Quintiles Clindepharm (Pty.) Limited

Quintiles Clinical and Commercial Nigeria Limited

Quintiles Colombia Ltda.

Quintiles Commercial (UK) Limited

Quintiles Commercial AB

Quintiles Commercial ApS

Quintiles Commercial Brasil Ltda.

Quintiles Commercial Europe Limited

Quintiles Commercial Finland OY

Quintiles Commercial Germany GmbH

Quintiles Commercial Italia S.r.L.

Quintiles Commercial Laboratrio S.L.U.

Quintiles Commercial Overseas Holdings Limited

Quintiles Commercial Portugal Unipressoal Ltda.

Quintiles Commercial Rus LLC

Quintiles Commercial South Africa (Pty) Limited

Quintiles Commercial US. Inc.

Quintiles Costa Rica S.A.

Quintiles Czech Republic, s.r.o.

Quintiles d.o.o. Beograd

Quintiles Denmark

Quintiles East Africa Limited

Quintiles East Asia Pte. Ltd.

Quintiles Eastern Holdings GmbH

Quintiles Egypt LLC

Quintiles Enterprise Management (Shanghai) Co. Ltd.

Quintiles Estonia OU

Quintiles Finance Sarl

Jurisdiction or 
State of Organization
North Carolina
Mexico

South Africa

Thailand

Sweden

Switzerland

Argentina

Austria

Netherlands

Belgium

Benin

Brazil

Bulgaria

Canada

Chile

South Africa

South Africa

Nigeria

Colombia

United Kingdom

Sweden

Denmark

Brazil

United Kingdom

Finland

Germany

Italy

Spain

United Kingdom

Portugal

Russia

South Africa

Delaware

Costa Rica

Czech Republic

Serbia

Denmark

Kenya

Singapore

Austria

Egypt

China

Estonia

Luxembourg

Subsidiary
Quintiles Finance Sarl - US
Quintiles Finance Uruguay, S.r.l.

Quintiles GesmbH

Quintiles GmbH

Quintiles Greece

Quintiles Guatemala, S.A.

Quintiles Holdings S.a.r.l.

Quintiles Hong Kong Limited

Quintiles Hungary Kft.

Quintiles IMS European Holdings I CV

Quintiles IMS Finance Ireland Designated Activity Company

Quintiles Ireland (Finance) Limited

Quintiles Ireland Limited

Quintiles Israel LTD.

Quintiles Istanbul Saglik Hizmetleri Arastirma ve Danismanlik Limited Sirketi

Quintiles Lanka Private Limited

Quintiles Latin America Inc.

Quintiles Latvia SIA

Quintiles Luxembourg European Holding S.a.r.l. - US

Quintiles Luxembourg European Holding, S.a.r.l.

Quintiles Luxembourg France Holdings SARL

Quintiles Malaysia Sdn. Bhd.

Quintiles Mauritius Holdings, Inc. 

Quintiles Medical Development (Dalian) Co. Ltd.

Quintiles Medical Development (Shanghai) Co. Ltd.

Quintiles Medical Education Inc.

Quintiles Mexico, S. de R.L. de C.V.

Quintiles Netherlands

Quintiles New Zealand

Quintiles Norway

Quintiles Novosibirsk

Quintiles OY

Quintiles Panama, Inc.

Quintiles Peru S.r.l.

Quintiles Phase One Clinical Trials India Private Limited

Quintiles Philippines, Inc.

Quintiles Pty. Limited

Quintiles Puerto Rico, Inc.

Quintiles Research (India) Private Limited

Quintiles Romania S.R.L.

Quintiles Russia

Quintiles Russia LLC

Quintiles S.a.r.l.

Quintiles S.a.r.L. - US

Jurisdiction or 
State of Organization
United States
Uruguay

Austria

Germany

Greece

Guatemala

Luxembourg

Hong Kong

Hungary

Netherlands

Ireland

Ireland

Ireland

Israel

Turkey

Sri Lanka

Argentina

Latvia

United States

Luxembourg

Luxembourg

Malaysia

Mauritius

China

China

New York

Mexico

Netherlands

New Zealand

Norway

Russia

Finland

Panama

Peru

India

Philippines

Australia

Puerto Rico

India

Romania

Russia

Russia

Luxembourg

United States

Subsidiary
Quintiles Site Services, S.A.
Quintiles Slovakia s.r.o.

Quintiles South Africa (PTY.) Limited

Quintiles St. Petersburg

Quintiles Staff Services Sp.A.

Quintiles Switzerland Sarl

Quintiles Taiwan Limited

Quintiles Transnational Japan K.K.

Quintiles Transnational Korea Co. Limited

Quintiles UAB

Quintiles UK (Japan Holdings) Limited

Quintiles Ukraine

Quintiles Vietnam, LLC

Quintiles West Africa Limited

Quintiles Zagreb d.o.o.

Redsite Limited

Reportive SA

RX India LLC

Schwarzeck Verlag GmbH

SecureConsent, LLC

Shanghai IMS Market Research Co. Ltd.

Source Informatics Limited

Spartan Leasing Corporation

STI Technologies Limited

Targeted Molecular Diagnostics, LLC

Tarius A/S

Temas Srl - Società Unipersonale

TforG Connect BVBA

TforG Support NV

The Amundsen Group, Inc.

Themis Limited

Themis North America Inc.

UAB IMS Health

ValueMedices Research, LLC

VCG&A Inc.

VCG-Bio, Inc.

Wingspan Technology Inc.

Jurisdiction or 
State of Organization
Costa Rica
Slovakia

South Africa

Russia

Italy

Switzerland

Taiwan

Japan

Korea

Lithuania

United Kingdom

Ukraine

Vietnam

Ghana

Croatia

United Kingdom

France

Delaware

Germany

Delaware

China

United Kingdom

Delaware

Canada

Illinois

Denmark

Italy

Belgium

Belgium

Massachusetts

United Kingdom

District of Columbia

Lithuania

Delaware

Massachusetts

Delaware

Pennsylvania

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in the Registration Statement on Form S-8 (Nos. 333-213927, 
333-193212, 333-188431) and Form S-3 (No. 333-218209) of IQVIA Holdings Inc. (formerly Quintiles IMS 
Holdings, Inc.) of our report dated February 16, 2018 relating to the financial statements, financial statement 
schedules and the effectiveness of internal control over financial reporting, which appears in this Form 10-K.

Exhibit 23.1

/s/ PricewaterhouseCoopers LLP

Raleigh, North Carolina
February 16, 2018

 
Exhibit 31.1 

CERTIFICATION OF PERIODIC REPORT UNDER SECTION 302 OF 

THE SARBANES-OXLEY ACT OF 2002 

I, Ari Bousbib, certify that: 

1. I have reviewed this annual report on Form 10-K of IQVIA Holdings Inc. (the “registrant”); 

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact 
necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with 
respect to the period covered by this report; 

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all 
material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in 
this report; 

4. The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as 
defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act 
Rules 13a-15(f) and 15d-15(f)) for the registrant and have: 

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under 
our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is 
made known to us by others within those entities, particularly during the period in which this report is being prepared; 

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be 

designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the 
preparation of financial statements for external purposes in accordance with generally accepted accounting principles; 

(c)

Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our 
conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this 
report based on such evaluation; and 

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the 
registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has 
materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; 
and 

5. The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial 
reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the 
equivalent functions): 

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting 

which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial 
information; and 

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the 

registrant’s internal control over financial reporting. 

Date: February 16, 2018 

/s/ Ari Bousbib
Ari Bousbib
Chairman, Chief Executive Officer and President
(Principal Executive Officer)

 
Exhibit 31.2 

CERTIFICATION OF PERIODIC REPORT UNDER SECTION 302 OF 

THE SARBANES-OXLEY ACT OF 2002 

I, Michael R. McDonnell, certify that: 

1. I have reviewed this annual report on Form 10-K of IQVIA Holdings Inc. (the “registrant”); 

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact 
necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with 
respect to the period covered by this report; 

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all 
material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in 
this report; 

4. The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as 
defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act 
Rules 13a-15(f) and 15d-15(f)) for the registrant and have: 

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under 
our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is 
made known to us by others within those entities, particularly during the period in which this report is being prepared; 

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be 

designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the 
preparation of financial statements for external purposes in accordance with generally accepted accounting principles; 

(c)

Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our 
conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this 
report based on such evaluation; and 

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the 
registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has 
materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; 
and 

5. The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial 
reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the 
equivalent functions): 

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting 

which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial 
information; and 

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the 

registrant’s internal control over financial reporting. 

Date: February 16, 2018 

/s/ Michael R. McDonnell
Michael R. McDonnell
Executive Vice President and Chief Financial Officer
(Principal Financial Officer)

 
CERTIFICATION PURSUANT TO 
18 U.S.C. SECTION 1350 
AS ADOPTED PURSUANT TO SECTION 906 
OF THE SARBANES-OXLEY ACT OF 2002 

Exhibit 32.1 

I, Ari Bousbib, Chairman, Chief Executive Officer and President of IQVIA Holdings Inc. (the “Company”), do hereby certify, 
pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that to the best of my 
knowledge: 

(1)

(2)

the Annual Report on Form 10-K of the Company for the year ended December 31, 2017 (the “Report”) fully complies 
with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and 

the information contained in the Report fairly presents, in all material respects, the financial condition and results of 
operations of the Company for the periods presented therein. 

Date: February 16, 2018 

/s/ Ari Bousbib
Ari Bousbib
Chairman, Chief Executive Officer and President
(Principal Executive Officer)

This certification is being furnished solely to accompany the Report pursuant to 18 U.S.C. § 1350, as adopted pursuant to Section 906 
of the Sarbanes-Oxley Act of 2002, and shall not be deemed “filed” by the Company for purposes of Section 18 of the Securities 
Exchange Act of 1934, as amended, and shall not be incorporated by reference into any filing of the Company under the Securities Act 
of 1933, as amended, or the Securities Exchange Act of 1934, as amended, whether made before or after the date of this Report, 
irrespective of any general incorporation language contained in such filing. 

A signed original of this written statement required by Section 906 of the Sarbanes-Oxley Act of 2002 has been provided to the 
Company and will be retained by the Company and furnished to the Securities and Exchange Commission or its staff upon request.  

CERTIFICATION PURSUANT TO 
18 U.S.C. SECTION 1350 
AS ADOPTED PURSUANT TO SECTION 906 
OF THE SARBANES-OXLEY ACT OF 2002 

Exhibit 32.2 

I, Michael R. McDonnell, Executive Vice President and Chief Financial Officer of IQVIA Holdings Inc. (the “Company”), do hereby 
certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that to the best of 
my knowledge: 

(1)

(2)

the Annual Report on Form 10-K of the Company for the year ended December 31, 2017 (the “Report”) fully complies 
with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and 

the information contained in the Report fairly presents, in all material respects, the financial condition and results of 
operations of the Company for the periods presented therein. 

Date: February 16, 2018 

/s/ Michael R. McDonnell
Michael R. McDonnell
Executive Vice President and Chief Financial Officer
(Principal Financial Officer)

This certification is being furnished solely to accompany the Report pursuant to 18 U.S.C. § 1350, as adopted pursuant to Section 906 
of the Sarbanes-Oxley Act of 2002, and shall not be deemed “filed” by the Company for purposes of Section 18 of the Securities 
Exchange Act of 1934, as amended, and shall not be incorporated by reference into any filing of the Company under the Securities Act 
of 1933, as amended, or the Securities Exchange Act of 1934, as amended, whether made before or after the date of this Report, 
irrespective of any general incorporation language contained in such filing. 

A signed original of this written statement required by Section 906 of the Sarbanes-Oxley Act of 2002 has been provided to the 
Company and will be retained by the Company and furnished to the Securities and Exchange Commission or its staff upon request.