Quarterlytics / Financial Services / Asset Management - Leveraged / Luminex Corporation

Luminex Corporation

lmnx · NASDAQ Financial Services
Claim this profile
Ticker lmnx
Exchange NASDAQ
Sector Financial Services
Industry Asset Management - Leveraged
Employees 501-1000
← All annual reports
FY2009 Annual Report · Luminex Corporation
Sign in to download
Loading PDF…
A N N U A L   R E P O R T   2 0 0 9

   L E A D E R S H I P   |   G L O B A L   E X P A N S I O N   |   A S S A Y S   |   P A R T N E R S   |   I N N O V A T I O N   |   P E O P L E 

Luminex is dedicated to our mission to improve the health,  
safety and quality of life for people around the world.

A   c o m m i t m e n t   t o   c u s t o m e r s .

L U M I N E X   A N N U A L   R E P O R T   2 0 0 9

L E T T E R   T O   S H A R E H O L D E R S

Fellow Shareholders:

2009 was an extraordinary year filled with unexpected events  
whose impact resonated around the world. At Luminex, we are  
very proud of the progress we have made through 2009. The events 
of the past year have included economic adversity, market challenges 
and an unpredicted pandemic. Thanks to the strong financial and 
operational foundation we established over the last several years,  
and the tremendous dedication of our people, Luminex was able  
to weather challenges and realize significant opportunities during  
this most unusual year. 

As we faced these challenges, the company continued to execute our 
strategic growth plan and maintained our focus on our customers 
while assisting them in solving their problems. As a result, Luminex 
further strengthened our position as the worldwide leader in 
multiplexed solutions, and advanced our mission of improving the 
health, safety and quality of life of people around the world. 

Despite uncertain economic conditions, we achieved many 
operational milestones, including record total revenue, record 
revenues from royalties, record systems revenue, record assay  
sales and record net income. The system revenue we achieved,  
in particular, in a year that featured unprecedented capital  
constraints is a true testament to the Luminex technology platform. 
By year end, we had increased the cumulative number of Luminex 
systems shipped worldwide to more than 6,700 and expanded  
our international presence into the growing Asia-Pacific market. 

Luminex’s Assay Group drove high growth by increasing adoption of 
our diagnostic tests worldwide. We achieved regulatory clearances 
and updates for our respiratory viral and cystic fibrosis tests around 
the world. Our xTAG® Respiratory Viral Panel (RVP) assay product 
line played an integral part in the fight against the 2009 Influenza 
A/H1N1 virus. We launched new tests and continued refinement 
and development of assays in areas as diverse as microRNA analysis, 
poultry flock monitoring, biothreat and newborn screening.

Luminex’s Technology Group made major contributions to our growth 
with further adoption of our Luminex 200 system in laboratories 
and clinics worldwide. We achieved full commercial launch of our 
FLEXMAP 3D® system for higher-volume laboratories, and delivered 
every milestone toward the final development of our MAGPIX™ 
system for smaller and lower-volume laboratories. 

We enriched our relationships with our strategic partners in 2009, 
collaborating to expand the reach of our xMAP® Technology into 
international markets and explore new xMAP-based applications  
in growth markets including biodefense and agro-biotechnology. 

We are proud of what Luminex accomplished in 2009, and are 
confident in our growth strategy, partner and product pipeline, and 
prospects for continued growth in 2010 and beyond. The market 
for innovation continues to be strong and demand for our xMAP 
Technology continues to grow. We believe Luminex is very well 
positioned to capture many exciting opportunities ahead. 

Looking toward the coming year, Luminex will continue to execute 
our strategic growth plan, creating the products and leveraging the 
collaborations that will allow us to reach additional customers and 
new markets. We will also maintain our focus on creating shareholder 
value as we strive toward improving the health, safety and quality  
of people worldwide. 

Thank you for your ongoing support and investment in Luminex.  
We look forward to a bright future. 

Sincerely,

Patrick J. Balthrop, Sr. 
Chief Executive Officer and President

 
 
P E R F O R M A N C E   H I G H L I G H T S

O V E R A L L   
A N N U A L   R E V E N U E 

Up 16 percent

2 0 0 9   R E V E N U E S   
W E R E   $ 1 2 0 . 6   M I L L I O N 

A N N U A L   
G R O S S   P R O F I T 

Up $10.3 Million

G R O S S   P R O F I T   M A R G I N   
F O R   T H E   Y E A R 
W A S   6 7   P E R C E N T 

A N N U A L   
O P E R A T I N G   I N C O M E 

Up 121 percent

2 0 0 9 
O P E R A T I N G   I N C O M E 
I N C R E A S E D 
$ 4 M   O V E R   2 0 0 8 
T O   $ 7 . 4 M

A S S A Y   
R E V E N U E   G R O W T H 

Up 66 percent

A S S A Y   S A L E S   W E R E   A   
R E C O R D   $ 3 1 . 1   M I L L I O N

R O Y A L T Y   
R E V E N U E   G R O W T H 

Up 23 percent

R O Y A L T Y   R E V E N U E S 
R E A C H E D 
$ 1 8 . 3   M I L L I O N

S Y S T E M   P L A C E M E N T S 

873 shipments

R O Y A L T Y - B E A R I N G   
E N D - U S E R   S A L E S

Up 18 percent

T H E R E   W E R E   6 , 7 6 7   
L U M I N E X   S Y S T E M S   I N   
T H E   M A R K E T   A T   
T H E   E N D   O F   2 0 0 9

R O Y A L T Y - B E A R I N G 
E N D - U S E R   S A L E S   R E A C H E D 
$ 2 8 1 . 8   M I L L I O N   
I N   2 0 0 9 

S Y S T E M   R E V E N U E 

Up 9 percent

I N   A   C H A L L E N G I N G   
C A P I T A L   M A R K E T ,   
L U M I N E X   H A D   
S Y S T E M   R E V E N U E   O F   
$ 3 0 . 7   M I L L I O N

C A S H   A N D   
I N V E S T M E N T S   A T   
D E C E M B E R   3 1 ,   2 0 0 9

$119.6 Million

L U M I N E X   H A S   
M A I N T A I N E D   A   S T R O N G 
B A L A N C E   S H E E T ,   
P R O V I D I N G   
S I G N I F I C A N T   
F L E X I B I L I T Y

 
R E V E N U E   M I X

2007

63%

2008

2009

54%

33%

13%

27%

10%

63%

26%

10%

64%

Royalty, Consumable and Assay

System

Other

C O N S U M A B L E   R E V E N U E
(in millions)

2009      

2008      

2007

R O Y A L T Y   R E V E N U E
(in millions)

2009      

2008      

2007

A S S A Y   R E V E N U E
(in millions)

2009      

2008      

2007

S Y S T E M   R E V E N U E
(in millions)

2009      

2008      

2007

$28.4

(22% CAGR, 2007–2009)

$31.7

$19.2

$18.3

(34% CAGR, 2007–2009)

$14.9

$10.2

$31.1

(66% CAGR, 2007–2009)

$18.7

$11.3

$30.7

(12% CAGR, 2007–2009)

$28.1

$24.4

T O T A L   R E V E N U E   (in millions)
(27% CAGR, 2004–2009)

$120.6

$104.4

$75.0

$53.0

$35.9

$42.3

2004

2005

2006

2007

2008

2009

C U M U L A T I V E   S Y S T E M   S H I P M E N T S

120,000

90,000

60,000

30,000

0

7,000

6,000

5,000

4,000

3,000

2,000

1,000

        0

2004

2005

2006

2007

2008

2009

F I V E   Y E A R   C U M U L A T I V E   T O T A L   R E T U R N *
(Among Luminex Corporation, the NASDAQ Composite Index and the NASDAQ Biotechnology Index)

$250

$200

$150

$100

 $50

2004

2005

2006

2007

2008

2009

Luminex Corporation

NASDAQ Composite

NASDAQ Biotechnology

*$100 invested on 12/31/04 in stock or index, including reinvestment of dividends.
Fiscal year ending December 31.

E X E C U T I O N   A N D   L E A D E R S H I P

Luminex delivered excellent financial and 
operational results in 2009, posting record 
revenues in several key areas, expanding 
our market reach, and growing our base 
of systems and assays. These results are an 
outcome of the strategic growth plan we 
have been executing since 2005 to increase 
revenues, improve profits and gross margins, 
drive adoption of our xMAP® Technology and 
build our pipeline of innovative products. 

2005 was a year of change as we began to 
transform Luminex from a technology-
based company to a market-driven and 
customer-focused business. We delivered new 
partnerships to expand use of our technology, 
strengthened our regulatory infrastructure 
and further grew our significant internal  
R&D investments. 

2006 was a year of development and 
achievement. We built on the progress 
achieved in 2005, delivered the initial results 
of our growing R&D investments and secured 

partnerships that would allow us to create 
new applications for our technology and 
reach new end users across both geographic 
markets and important industry sectors.  

2007 was a transformational year in which we 
completed the acquisition of Tm Bioscience 
to create Luminex Molecular Diagnostics 
and launch our company into the important, 
growing molecular diagnostics market. 

2008 was a record-breaking year of many 
accomplishments. Record operational and 
financial results. The launch of products 
including the first assay of its type ever 
to be cleared by the U.S. Food and Drug 
Administration (FDA), the xTAG® 
Respiratory Viral Panel. The first commercial 
shipment of our FLEXMAP 3D® system, 
and the establishment of many important 
new partnerships with companies including 
Becton Dickinson, Tyson Foods and  
Abbott Molecular.

2009 was a unique and challenging year, 
but we set new records as we built on the 
tremendous foundation that had been 
established throughout the previous years. 
Our total revenues reached $120.6 million, 
a 16 percent increase over 2008, despite 
unprecedented economic constraints across 
our industry. With cumulative instrument 
shipments of 6,767 instruments worldwide, 
our total number of system placements 
today is many times higher than that of any 
other multiplexing company in the world, 
underscoring our position as the worldwide 
leader in multiplexed solutions. 

The market for Luminex’s xMAP Technology 
is very large and expanding, and we 
are working both independently and in 
cooperation with our partners to capture 
these opportunities. We have the resources, 
expertise, relationships and financial strength 
to position Luminex for continued growth 
and industry leadership in 2010. 

    B R A D   C R U T C H F I E L D   |   V I C E   P R E S I D E N T   A N D   G R O U P   M A N A G E R ,   L I F E   S C I E N C E ,   B I O - R A D

“ The Asia-Pacific region is an essential, growing life sciences market.  
There is strong demand for Luminex technology, and many projected  
growth opportunities.” 

G L O B A L   E X P A N S I O N

A key element of Luminex’s growth strategy is driving adoption of our 
multiplexing technology around the world. In 2009, to complement 
our headquarters in Austin, Texas and locations in Toronto, Canada 
and Amsterdam, The Netherlands, we expanded our corporate 
footprint to include facilities in Shanghai in the People’s Republic of 
China and Tokyo, Japan. 

significant. Through our efforts and the work of our partners over 
the last several years, Luminex systems can be found in research 
institutions and laboratories throughout Asia-Pacific. We established 
new offices in China and Japan to drive further expansion and allow 
us to provide additional support, sales, training and services to our 
customers and partners throughout the Asia-Pacific market.  

The Asia-Pacific region is an important growth market for Luminex, 
and is home to one of the fastest-growing life science markets in 
the world, where the opportunity for xMAP Technology adoption is 

In our first months of operation in China and Japan, we have been 
hard at work establishing new local partnerships and are excited  
about the possibilities ahead. 

Vancouver

Calgary

Spokane

Seattle

Portland

Minneapolis

Milwaukee

Omaha

Chicago

Ottawa

Buffalo

Philadelphia

Baltimore

New York

San Francisco

Oakland

Los Angeles

San Diego

Boulder

Kansas City

St. Louis

Washington D. C.

Norfolk

Memphis

Charlotte

Birmingham

Dallas

Houston

New Orleans

Jacksonville

Tampa

Havana

Mexico City

Nuuk 

Reykjavik

Torshavn

Oslo

Helsinki

Stockholm

Copenhagen

Berlin

Warsaw

Lviv

Kiev

Rostov

Moscow

Minsk

Perm

Izevsk

Ufa

Tol Yatti

Kuybyshev

Jaroslavl

Gorkiy

Kazan

Saratov

Volgograd

Frunze

Bucharest

Krasnodar

Dublin

London

Cork

Paris

Nantes

Toulouse

Sverdlovsk

Chelyabinsk

Omsk

Novosibirsk

Krasnojarsk

Irkutsk

Ponta Delgada

Porto

Madrid

Barcelona

Rome

Lisbon

Sevilla

Algiers

Gibraltar

Rabat

Tunis

Tripoli

Izmir

Athens

Ankara

Adana

Cairo

Tashkent

Ashgabat

Kabul

Islamabad

Multan

Tehran

Esfahan

Shiraz

Baghdad

Basra

Riyadh

Qaraghandy

Ulaanbaatar

Frunze

Almaty

Urumqi

Baotou

Beijing

Yinchuan

Xining

Taiyuan

Qiqihar

Harbin

Jixi

Fuxin

Jilin
Benxi

Sapporo

Pyongyang

Seoul

Sendai

Tokyo

New Delhi

Jaipur

Agra

Kathmandu

Allahabad

Dhaka

Ahmadabad

Surat

Nagpur

Calcutta

Muscat

Xuzhou
Hefei

Chengdu

Zigong

Huangshi

Yueyang

Shanghai

Ningbo

Dukou

Guiyang

Wenzhou
Wenzhou

Taipai

Fuzhou

Xiamen

Nanning

Shantou

Hanoi

Hong Kong

Bombay

Pune

Varanasi

Rangoon

Vientiane

Madras

Cochin

Colombo

Bangkok

Manila

Phnom Penh

Ho Chi Minh City

Kuala Lumpur

Davao

Nouakchott

Praia

Dakar

Bamako

Niamey

Khartoum

Asmara

Sanaa

Caracas

Bogota

Georgetown

Paramaribo

Conakry

Freetown

Abuja

Porto Novo

Monrovia

Abidjan

Accra

Lome

Bangui

N'Djamena

Jakarta

Port Moresby

Perth

Adelaide

Sydney

Canberra

Melbourne

Brisbane

Auckland

Wellington

Addis Abbaba

Dar es Salaam

Yaounde

Libreville

Kampala

Nairobi

Mogadishu

Kinshasa

Luanda

Huambo

Likasi

Lusaka

Harare

Antananarivo

Windhoek

Walvis Bay

Gaborone

Pretoria

Mbabane

Maputo

Bloemfontein

Umtata

Cape Town

Quito

Lima

Manaus

Belem

Fortaleza

Sao Goncalo

Recife

Brasilia

Salvador

La Paz

Sucre

Goiania

Belo Horizonte

Campinas

Curitiba

Sao Paulo

Rio De Janeiro

Asuncion

Porto Alegre

Santiago

Rosario

Buenos Aires

Montevideo

Port Stanley

A S S A Y S 

2009 was a landmark year for Luminex’s 
Assay Group, featuring increased sales, 
product advancements, the achievement 
of regulatory milestones and new launches 
around the world. 

was recognized as an important tool and 
proved to be a comprehensive way for patients 
infected with common respiratory viruses 
to be distinguished from those potentially 
infected with the pandemic influenza strain.

For many, 2009 will be remembered as the 
year of the Influenza A/H1N1 pandemic.  
The World Health Organization reported that, 
from April 2009 through January 2010, more 
than 200 countries and overseas territories 
or communities had reported laboratory-
confirmed cases of 2009 Influenza A/H1N1. 

The pandemic and the necessity for fast, 
reliable respiratory viral testing accelerated 
adoption of xTAG RVP in many laboratories. 
We expect that labs’ experiences with this 
innovative test and xMAP® Technology in 
such an extraordinary circumstance has 
created lasting customers for the product.

Luminex was proud to be responsive to  
our customers and involved in efforts  
to monitor and control the pandemic.  
Our team collaborated with public health  
officials, laboratories and partners as the  
virus spread from the late spring through 
early winter. Because of its ability to detect 
many respiratory viruses at once, our  
xTAG® Respiratory Viral Panel (RVP)  

Further advancing our work in respiratory 
viral detection, we launched xTAG RVP 
Fast in Europe in 2009. We are following 
regulatory approval processes to launch the 
test in other regions of the world.

In addition to our xTAG RVP advancements 
in 2009, we continued to increase sales 
of assays including our Ashkenazi Jewish 

Panel and Pneumococcal 14 assay. We also 
enhanced our line of cystic fibrosis products, 
launching xTAG Cystic Fibrosis 39 v2 in the 
U.S. and Europe, and launching in Europe 
xTAG Cystic Fibrosis 71 v2, which screens for 
71 CF-causing gene mutations using a faster 
and simpler protocol. We look forward to 
launching xTAG Cystic Fibrosis 60 v2, which 
detects 60 mutations more easily and faster, 
in the U.S. in 2010. 

Luminex continued refinement of our 
FlexmiR® line of products in 2009, launching 
FlexmiR v2, a faster, easy-to-use, highly 
sensitive method for microRNA detection and 
quantitation. We also continued development 
of our pipeline of assays including our 
newborn screening test, NeoPlex4™, our novel 
GI panel and our poultry flock monitoring 
assay. We expect to launch these assays in 
several countries by the end of 2010. 

   C H R I S T I N E   G I N O C C H I O ,   P H . D .   |    S E N I O R   D I R E C T O R   O F   I N F E C T I O U S   D I S E A S E   D I A G N O S T I C S ,   

N O R T H   S H O R E - L I J   H E A L T H   S Y S T E M   L A B O R A T O R I E S

“ During the influenza pandemic, xTAG RVP helped our lab perform 
sensitive molecular testing, and gauge the actual magnitude of the 
H1N1 outbreak.”

S T R A T E G I C   P A R T N E R S H I P S

A critical component of Luminex’s growth has been our network 
of strategic partners. Comprised of industry-leading, innovative 
companies, our partner base has been integral in expanding  
Luminex’s reach into new geographic markets and industry sectors, 
and creating new applications for our xMAP Technology to power  
new developments in healthcare, life sciences, agro-biotechnology  
and biodefense.  

In 2009, we saw many partnerships flourish. Long-standing partners 
such as Bio-Rad Laboratories and One Lambda continued to leverage 

xMAP-based products to advance science and healthcare.  
Our distribution partners, including Abbott Molecular and  
Fisher Healthcare, increased penetration worldwide by distributing 
Luminex assays. Luminex developed new agreements to deliver 
additional products to key customers. Millipore, a long-standing 
Luminex partner, signed an agreement to add the FLEXMAP 3D® 
system to its Luminex suite of products to serve their international 
customer base of academic, reference and pharmaceutical  
research laboratories.

I N N O V A T I O N

In addition to the research and development work conducted by our 
partners and customers, Luminex maintains a robust R&D operation 
dedicated to advancing our technology. Innovation is the core of 
Luminex’s business and we are constantly striving to develop new 
products for scientists working in diverse disciplines. 

Continuous investment in the expansion of our offerings helps us 
extend our market-leading position and ensures that we launch 
products vital to the customers we serve. xMAP® Technology and our 
systems, assays and analysis software play a crucial role in meeting  
our customers’ evolving needs. 

In 2009, we saw the launch of exciting new products and the 
achievement of key milestones for many of our pipeline products. 

In systems, we delivered the full commercial launch of FLEXMAP 
3D® to create a multiplexing solution for scientists in high-throughout 
laboratories. FLEXMAP 3D was developed with our unique blend 
of innovation and product development discipline, and its design is 
based on years of customer feedback. FLEXMAP 3D can conduct 500 
simultaneous tests on one sample, and allow scientists to process up  
to 144,000 data points in less than an hour. It is an ideal system for 
higher-volume laboratories. 

FLEXMAP 3D is an example of the significant investments we have 
made in delivering our platform product line strategy. The next 
exciting platform offering in this strategy will be MAGPIX™, a system 
designed for smaller, lower-volume laboratories. We look forward to 
launching MAGPIX in 2010. 

In assays, we began to roll out the next generations of our xTAG® 
Respiratory Viral Panel, xTAG Cystic Fibrosis line and FlexmiR® 
microRNA assay in 2009. These unique tests, which are streamlined, 
easier to use and more efficient versions of their predecessors, were 
enhanced and improved based on suggestions from clinicians, 
scientists and researchers. We have an exciting pipeline of additional 
innovative assays in development. 

In software, 2009 saw the release of our xPONENT® 3.1 software. 
Developed with direct input from users across a range of research  
and clinical diagnostic disciplines, the software features more than  
65 new enhancements that allow scientists to work more efficiently 
and effectively. 

As a result of our continuous development, Luminex’s xMAP 
Technology is protected by more than 89 patents and 215  
patents pending.

Luminex was recognized in  

The Wall Street Journal for Technology  

Innovation for xTAG RVP and honored  

as Most Innovative Company for 2009  

at the American Business Awards.

  W A Y N E   R O T H ,   P H . D .   |   C H I E F   E N G I N E E R   R & D   |   L U M I N E X   E M P L O Y E E   F O R   1 2   Y E A R S

“ At the end of the day, improving the lives of people is what our work  
at Luminex is all about. Better medicines, faster diagnoses, safer food.  
It’s a good feeling to know that the work I do truly makes a difference.”

P E O P L E

While our growth strategy is driven by our 
technology, partnerships, products and 
innovation, it is people who are at the center 
of everything Luminex does. Our customers, 
partners, employees and shareholders are 
integral to our operations. They drive our 
advances and it is through their dedication 
that we continue to succeed. We all share a 

passion and dedication to fostering the health 
and safety of humankind. 

Our growth is truly sustainable for the long 
term if we can continue to positively impact 
human lives. A new assay holds the potential 
to create a faster way to identify a genetic 
disease in a child. A new system can mean a 

quicker route to a new medical therapy. Our 
xMAP Technology improves performance and 
outcomes while making research and delivery 
of healthcare more efficient and less costly. 
With our attention focused on improving the 
health, safety and quality of life of people, our 
opportunities are bright. 

C O R P O R AT E   O F F I C E R S

V I C E   P R E S I D E N T S

B O A R D   O F   D I R E C T O R S

Patrick J. Balthrop, Sr.
Chief Executive Officer
and President

Russell W. Bradley
Vice President
Business Development
and Strategic Planning

Steven Back
Vice President
Manufacturing

Timothy R. Dehne
Vice President
Systems Research  
and Development

Jeremy Bridge-Cook, Ph.D.
Senior Vice President
Assay Group

Andrew D. Ewing
Vice President
Technical Operations

Harriss T. Currie
Chief Financial Officer 
Vice President
Treasurer

Nancy Krunic, Ph.D.
Vice President
Luminex Molecular  
Diagnostics 

Gregory J. Gosch
Vice President
Luminex Bioscience Group

Darin S. Leigh
Vice President
Commercial Operations

Michael F. Pintek
Senior Vice President
Operations

David S. Reiter
Vice President
General Counsel
and Corporate Secretary

Oliver H. Meek
Vice President
Quality Assurance
and Regulatory Affairs

G. Walter Loewenbaum, II (1)
Chairman of the Board;
Chief Executive Officer and  
Chairman of the Board,
Mumboe Corp.
Chairman of the Board,
3D Systems Corporation

Patrick J. Balthrop, Sr. (1) (5)
Chief Executive Officer
and President

Robert J. Cresci (2)(4)
Managing Director, Pecks 
Management Partners Ltd.
Director, ContinuCare
Corporation
Director, j2 Global
Communications, Inc.

Thomas W. Erickson (1)(2)
Chairman of the Board,
Inmar, Inc.

Fred C. Goad, Jr. (3)
Member, Voyent Partners, LLC

Jay B. Johnston (3)(5)
Chairman of the Board,
QuesTek Innovations, LLC

Jim D. Kever (3)
Member, Voyent Partners, LLC
Director, 3D Systems  
Corporation
Director, Emdeon, Inc.
Director, Tyson Foods, Inc.

Kevin M. McNamara (2)
Director, Tyson Foods, Inc.

Edward A. Ogunro, Ph.D. (5)
Director, Applied  
NeuroSolutions, Inc.

Gerard Vaillant (3)(4)(5)
Retired Company Group
Chairman, Johnson & Johnson
Director, Sensors for Medicine
and Science, Inc.  
Director, Tecan AG
Director, OncoMethylome
Sciences

(1)  Member of the Executive Committee
(2) Member of the Audit Committee 
(3) Member of the Compensation Committee
(4)  Member of the Nominating and  

Corporate Governance Committee

(5)  Member of the Strategy and  
Development Committee

Independent Registered Public Accountants
Ernst & Young LLP
Austin, Texas

Annual Meeting of Stockholders
The annual meeting of stockholders will be held on Thursday, May 20, 2010  
at 10:00 a.m. local time at the Austin Airport Hilton, Austin, Texas.

Transfer Agent and Registrar
Mellon Investor Services, LLC
480 Washington Boulevard
Jersey City, New Jersey 07310
1.866.635.6965

Form 10-K/Investor Contact
A copy of the Company’s Annual Report on Form 10-K, filed with the Securities  
and Exchange Commission, may be obtained from the Company at no charge.  
Requests for the Annual Report on Form 10-K and other investor information 
should be directed to Investor Relations at the Company’s corporate office or  
www.luminexcorp.com or by e-mail to: investor@luminexcorp.com

Cautionary Note Regarding 
Forward-Looking Statements
This report contains forward-looking statements 
(all statements other than those made solely 
with respect to historical fact) under the Private 
Securities Litigation Reform Act of 1995. These 
forward-looking statements, including statements 
regarding our future financial position, business 
strategy, new products, assay sales, budgets, 
liquidity, cash flows, projected costs, litigation 
costs, including the costs or impact of any litigation 
settlements or orders, regulatory approvals or the 
impact of any laws or regulations applicable to us, 
and plans and objectives of management for future 
operations, are subject to known and unknown 
risks and uncertainties (some of which are 
beyond the Company’s control) that could cause 
actual results to differ materially and adversely 
from those anticipated in the forward-looking 
statements. See the Company’s 10-K filing for more 
detailed disclosure regarding forward-looking 
statements and associated risks and uncertainties.

In 2010, we will continue to execute our growth plan,
advance our product pipeline and enhance relationships
with key partners.

United States Headquarters
Luminex Corporation
12212 Technology Boulevard
Austin, Texas 78727
United States
512.219.8020

Europe
Luminex B.V.
Krombraak 15
4906 Oosterhout
The Netherlands
+31.16.240.8333

Canada
Luminex Molecular Diagnostics
439 University Avenue, Suite 900
Toronto, Ontario M5G 1Y8
Canada
416.593.4323

Japan
Luminex Japan  
Corporation Ltd.
Kamiyacho Sankei Bldg 3F
1-7-2 Azabudai
Minato-ku, Tokyo 106-0041
Japan
+81.3.5545.7440

China
Luminex Shanghai Trading Co. Ltd
Unit 6405, Building 6
No. 339 Cai Lun Rd.
Zhangjiang Hi-Tech Park of
Pudong District
Shanghai 201203, PRC
China
+021.61650809/61650810

w w w . l u m i n e x c o r p . c o m

UNITED STATES 
SECURITIES AND EXCHANGE COMMISSION  
WASHINGT0N, D.C. 20549  

FORM 10-K  

(cid:0)

(cid:2)

Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

for the fiscal year ended December 31, 2009  

or  

Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

for the transition period from                      to                     .  

Commission File No. 000-30109  

LUMINEX CORPORATION  

(Exact name of registrant as specified in its charter) 

DELAWARE
(State or other jurisdiction of 
incorporation or organization) 

12212 TECHNOLOGY BLVD., AUSTIN, TEXAS
(Address of principal executive offices) 

74-2747608
(I.R.S. Employer
Identification No.)

78727
(Zip Code)

(512) 219-8020 
(Registrant’s telephone number, including area code)  

Securities registered pursuant to Section 12 (b) of the Act:  

Title of each class
Common Stock, $0.001 par value 
Rights to Purchase Series A Junior Participating Preferred 
Stock, $0.001 par value 

Name of exchange on which registered
The NASDAQ Global Market
The NASDAQ Global Market

Securities registered pursuant to Section 12 (g) of the Act: NONE  

Indicate  by  check  mark  if  the  registrant  is  a  well-known  seasoned  issuer,  as  defined  in  Rule 405  of  the  Securities  Act. 
(cid:0)

(cid:2)

 No 

Indicate by check mark if  the  registrant is not  required  to file reports pursuant  to Section 13 or Section  15(d) of the Act. 
(cid:2)

(cid:0)

 No 

Yes 

Yes 

Indicate by  check mark  whether the Registrant: (1) has filed all reports required to be filed by  Section 13 or  15(d) of the 
Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the Registrant was required to 
file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes 

 No 

(cid:0)

(cid:2)

Indicate  by  check  mark  whether  the  registrant  has  submitted  electronically  and  posted  on  its  corporate  Web  site,  if  any, 
every  Interactive  Data  File  required  to  be  submitted  and  posted  pursuant  to  Rule 405  of  Regulation S-T  (§232.405  of  this 
chapter)  during  the  preceding  12 months  (or  for  such  shorter  period  that  the  registrant  was  required  to  submit  and  post  such 
files). Yes 

 No 

(cid:2)

(cid:2)

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K (§229.405 of this chapter) 
is  not  contained  herein,  and  will  not  be  contained,  to  the  best  of  Registrant’s  knowledge,  in  definitive  proxy  or  information 
statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K. 

(cid:2)

  
  
  
  
  
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a 
smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company”
in Rule 12b-2 of the Exchange Act.  

Large accelerated filer 

(cid:2)

   Accelerated filer

(cid:0)

Non-accelerated filer 
 (Do not check if a smaller reporting company) 

(cid:0)

 Smaller reporting company 

(cid:0)

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act). Yes 

(cid:0)

(cid:2)

 No 

Based on the closing sale price of common stock on The NASDAQ Global Market on June 30, 2009, the aggregate market 
value of the voting stock held by non-affiliates of the Registrant was $683,940,619 as of such date, which assumes, for purposes 
of  this  calculation  only,  that  all  shares  of  common  stock  beneficially  held  by  officers  and  directors  are  shares  owned  by 
“affiliates”.  

There were 41,844,572 shares of the Company’s Common Stock, par value $0.001 per share, outstanding on February 23, 

2010.  

DOCUMENTS INCORPORATED BY REFERENCE  

Portions  of  the  Registrant’s  Proxy  Statement  for  its  2010 Annual  Meeting  of  Stockholders  are  incorporated by  reference 

into Part III hereof.  

  
   
 
  
  
  
 
 
  
 
 
 
 
LUMINEX CORPORATION  

FORM 10-K 
FOR THE YEAR ENDED DECEMBER 31, 2009  

TABLE OF CONTENTS  

PART I

  PAGE

Item 1. 

  Business

Item 1A.    Risk Factors

Item 1B.    Unresolved Staff Comments

Item 2. 

  Properties

Item 3. 

  Legal Proceedings

Item 4. 

  Submission of Matters to a Vote of Security Holders

PART II

Item 5. 

Market for the Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of 
Equity Securities

Item 6. 

  Selected Financial Data

Item 7. 

  Management’s Discussion and Analysis of Financial Condition and Results of Operations

Item 7A.    Quantitative and Qualitative Disclosures about Market Risk

Item 8. 

  Financial Statements and Supplementary Data

Item 9. 

  Changes in and Disagreements with Accountants on Accounting and Financial Disclosure

Item 9A.    Controls and Procedures

Item 9B.    Other Information

Item 10.    Directors, Executive Officers and Corporate Governance

Item 11.    Executive Compensation

PART III

Item 12. 

Security Ownership of Certain Beneficial Owners and Management and Related Stockholder 
Matters

Item 13.    Certain Relationships and Related Transactions, and Director Independence

Item 14.    Principle Accounting Fees and Services

PART IV

Item 15.    Exhibits, Financial Statement Schedules

Signatures and Certifications

1

19 

31

31 

31

31

32

35

36

55 

56

91

91

92

92

92

92

93

93

94

S-1

                                   
   
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
  
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
  
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
  
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
  
 
 
 
 
Safe Harbor Cautionary Statement  

This  annual  report  on  Form  10-K  contains  statements  that  are  forward-looking  statements  under  the  Private  Securities 
Litigation  Reform  Act  of  1995.  Forward-looking  statements  give  our  current  expectations  of  forecasts  of  future  events.  All 
statements other than statements of current or historical fact contained in this annual report, including statements regarding our 
future financial position, business  strategy, new products, assay sales, budgets, liquidity, cash flows, projected  costs,  litigation 
costs,  including  the  costs  or  impact  of  any  litigation  settlements  or  orders,  regulatory  approvals  or  the  impact  of  any  laws  or 
regulations applicable to us, and plans and objectives of management for future operations, are forward-looking statements. The 
words  “anticipate,”  “believe,”  “continue,”  “should,”  “estimate,”  “expect,”  “intend,”  “may,”  “plan,”  “projects,”  “will,”  and 
similar expressions, as they relate to us, are intended to identify forward-looking statements. These statements are based on our 
current plans and actual future activities, and our financial condition and results of operations may be materially different from 
those set forth in the forward-looking statements as a result of known or unknown risks and uncertainties, including, among other 
things:  

•

•

•

•

•

•

•

•

•

•

•

•

•

•

•

•

  risks and uncertainties relating to market demand and acceptance of our products and technology; 

  dependence on strategic partners for development, commercialization and distribution of products; 

  the  impact  of  the  ongoing  uncertainty  in  U.S.  and  global  finance  markets  and  changes  in  government  funding,
including its effects on the capital spending policies of our partners and end users and their ability to finance purchases
of our products; 

  concentration of our revenue in a limited number of strategic partners some of which may be experiencing decreased
demand  for their products  utilizing  or  incorporating  our  technology  and  budget  or  finance constraints  in  the  current
economic environment or periodic variability in their purchasing patterns or practices;

  fluctuations  in  quarterly  results  due  to  a  lengthy  and  unpredictable  sales  cycle,  bulk  purchases  of  consumables,

fluctuations in product mix, and the seasonal nature of some of our assay products;

  our ability to obtain and enforce intellectual property protections on our products and technologies; 

  reliance on third party distributors for distribution of specific assay products;

  our ability to scale manufacturing operations and manage operating expenses, gross margins and inventory levels;

  potential shortages, or increases in costs, of components or other disruptions to our manufacturing operations;

  competition; 

  our ability to successfully launch new products; 

  the timing of regulatory approvals; 

  the implementation, including any modification, of our strategic operating plans;

  the uncertainty regarding the outcome or expense of any litigation brought against or initiated by us; 

  risks relating to our foreign operations; and 

  risks and uncertainties associated with implementing our acquisition strategy including our ability to obtain financing,
our ability to integrate acquired companies or selected assets into our consolidated business operations, and the ability
to recognize the benefits of our acquisitions. 

Many of  these  risks, uncertainties  and other  factors  are  beyond our control  and are  difficult  to  predict. Any or  all  of our 
forward-looking statements in this annual report may turn out to be inaccurate. We have based these forward-looking statements 
largely  on  our  current  expectations  and  projections  about  future  events  and  financial  trends  that  we  believe  may  affect  our 
financial condition, results of operations, business strategy and financial needs. New factors could also emerge from time to time 
that could adversely  affect  our business. The forward-looking statements herein can be affected by inaccurate assumptions we 
might  make  or  by  known  or  unknown risks, uncertainties  and  assumptions, including  the risks, uncertainties  and  assumptions 
outlined  above  and  described  in  Item 1A  “Risk  Factors”  below.  In  light  of  these  risks,  uncertainties  and  assumptions,  the 
forward-looking events and circumstances discussed in this annual report may not occur and actual results could differ materially 
from those anticipated or implied in the forward-looking statements. When you consider these forward-looking statements, you 
should keep in mind these risk factors and other cautionary statements in this annual report including in Item 7 “Management’s 
Discussion and Analysis of Financial Condition and Results of Operations” and in Item 1A “Risk Factors.”  

                                   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Our  forward-looking  statements  speak  only  as  of  the  date  made.  We  undertake  no  obligation  to  publicly  update  or  revise 
forward-looking statements, whether as a result of new information, future events or otherwise. All subsequent written and 
oral forward-looking statements attributable to us or persons acting on our behalf are expressly qualified in their entirety by 
the cautionary statements contained in this annual report.  

Unless  the  context  requires  otherwise,  references  in  this  Annual  Report  on  Form  10-K  to  “Luminex,”  the  “Company,” 

“we,” “us” and “our” refer to Luminex Corporation and its subsidiaries.  

Luminex®,  xMAP®,  xTAG®,  Luminex®  100™,  Luminex®  200™,  Luminex®  XYP™,  Luminex®  SD™,  Luminex  HTSTM, 
FLEXMAP  3D®,  MicroPlex®,  MagPix™,  MagPlex®,  SeroMAP™,  xPONENT®,  and  FlexmiR®  are  trademarks  of  Luminex 
Corporation. This report also refers to trademarks, service marks and trade names of other organizations.  

                                   
   
ITEM 1. BUSINESS  

Overview  

PART I  

We develop, manufacture and sell proprietary biological testing technologies and products with applications throughout the 
life sciences and diagnostics industries. These industries depend on a broad range of tests, called bioassays, to perform diagnostic 
tests,  discover  and  develop  new  drugs  and  identify  genes.  Our  xMAP®  (Multi-Analyte  Profiling)  technology,  an  open 
architecture,  multiplexing  technology,  allows  simultaneous  analysis  of  up  to  500  bioassays  from  a  small  sample  volume, 
typically a single drop of fluid, by reading biological tests on the surface of microscopic polystyrene beads called microspheres. 
xMAP  technology  combines  this  miniaturized  liquid  array  bioassay  capability  with  small  lasers,  digital  signal  processors  and 
proprietary  software  to  create  a  system  offering  advantages  in  speed, precision,  flexibility  and  cost.  Our  xMAP  technology  is 
currently  being  used  within  various  segments  of  the  life  sciences  industry  which  includes  the  fields  of  drug  discovery  and 
development,  clinical  diagnostics,  genetic  analysis,  bio-defense,  protein  analysis  and  biomedical  research.  Our  business  is 
currently  organized  into  two  reportable  segments:  the  technology  segment  and  the assay  segment.  Our  products  are described 
below under “Products.”  

The technology segment was initially built around strategic partnerships. As of December 31, 2009, we had approximately 
68 strategic partners, 39 of which have developed reagent-based products utilizing our technology. Luminex and these partners 
have  sold  over  6,760  xMAP-based  instruments  in  laboratories  worldwide  as  of  December 31,  2009.  We  license  our  xMAP 
technology to our partners, who then develop products that incorporate the xMAP technology into products that they sell to end 
users.  We  also  develop  and  manufacture  the  proprietary  xMAP  laboratory  instrumentation  and  the  proprietary  xMAP 
microspheres  and  sell  these  products  to  our  partners.  When  our  partners  sell  xMAP-based  reagent  consumable  products  or 
xMAP-based  testing  services,  which run on the  xMAP  instrumentation, to end  users, such as testing laboratories,  we  obtain  a 
royalty on the sales from the partner. Luminex was founded on this model, and much of our success to date has been due to this 
model.  

The  assay  segment consists  of  Luminex  Bioscience Group,  or LBG, and Luminex Molecular  Diagnostics,  or  LMD.  This 
segment is primarily involved in the development and sale of assays utilizing xMAP technology on our installed base of systems. 
The  assay  segment  augments  our  partnership  model  with  a  distribution  model,  designed  to  take  advantage  of  our  increasing 
installed base of xMAP-based instrumentation. LBG introduced our first two assay products in late 2006.  

LMD, which we created upon our acquisition of Tm Bioscience in March 2007, is focused on multiplexed applications for 
the human molecular clinical diagnostics market. Tm Bioscience focused on the three segments of the genetic testing market for 
which it was developing products: human genetics, personalized medicine and infectious disease. Tm Bioscience had established 
a  solid  position  in  the  marketplace  with  their  product  development  and  FDA-compliant  manufacturing  capabilities.  We 
substantially completed the integration of Tm Bioscience during 2007, and we believe that with Tm Bioscience fully integrated, 
we  are  in  a  position  to  take  advantage  of  the  complementary  strengths  of  both  companies  in  molecular  diagnostics.  In 
January 2008,  the  assay  segment  launched  xTAG®  Respiratory  Viral  Panel  (RVP),  which  is  the  first  Food  and  Drug
Administration  (FDA) cleared  assay  to  simultaneously  detect  and  identify  12  viruses  and  viral  subtypes  that  together  are 
responsible for more than 85 percent of respiratory viral infections.  

1

                                   
   
We  have  established  a  leading  position  in  several  segments  of  the  life  sciences  industry  by  developing  and  delivering 
products  that  meet  customer  and  partner  needs  in  specific  market  segments,  including  multiplexing,  accuracy,  precision, 
sensitivity,  specificity,  reduction  of  labor  and  ability  to  test  for  proteins  and  nucleic  acids.  These  needs  are  addressed  by  our 
proprietary  technology,  xMAP  Technology,  which  allows  the  end  user  in  a  laboratory  to  perform  biological  testing  in  a 
multiplexed format. Multiplexing allows for many different laboratory results to be generated from one sample at one time. This 
is important because our end user customers and partners, which include laboratory professionals performing research, clinical 
laboratories performing tests on patients as ordered by a physician and other laboratories, have a fundamental need to perform 
high  quality  testing  as  efficiently  as  possible.  Until  the  availability  of  multiplexing  technology  such  as  xMAP,  the  laboratory 
professional had to perform one test on one sample in a sequential manner, and if additional testing was required on that sample, 
a second procedure would be performed to generate the second result, and so on until all the necessary tests were performed. By 
using  xMAP  technology,  these  end  users  have  the  opportunity  to  become  more  efficient  by  generating  multiple  simultaneous 
results per sample. We believe that this technology may also offer advantages in other industries, such as the food safety/animal 
health,  newborn  screening  and  bio-defense/bio-threat  markets.  Using  the  products  Luminex  has  available  today,  up  to  500 
simultaneous analyte results can be generated from a single sample.  

Luminex was incorporated under the laws of the State of Texas in May 1995, and we began commercial production of our 
Luminex 100 System in 1999. We were reincorporated in the State of Delaware in July 2000. Our shares of common stock are 
traded  on  the  Nasdaq  Global  Market  under  the  symbol  “LMNX.”  Our  principal  executive  offices  are  located  at  12212 
Technology  Blvd.,  Austin,  Texas  78727,  and  our 
is 
www.luminexcorp.com. Our Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q, Current Reports on Form 8-K, and 
amendments to these reports filed or furnished pursuant to Section 13(a) or 15(d) of the Securities Exchange Act of 1934, are 
available free of charge through our website as soon as reasonably practicable after such material is electronically filed with, or 
furnished to, the Securities and Exchange Commission, or the SEC. Information contained  or  accessible  on  our website is not 
incorporated  by  reference  into  this  report  and  such  information  should  not  be  considered  to  be  part  of  this  report  except  as 
expressly incorporated herein. The public may read and copy these materials at the SEC’s public reference room at 100 F Street, 
N.E., Washington, D.C. 20549 or on the SEC’s website at http://www.sec.gov. The SEC’s website contains reports, proxy and 
information  statements,  and  other  information  regarding  issuers  that  file  electronically  with  the  SEC.  Questions  regarding  the 
public reference room may be directed to the SEC at 1-800-732-0330.  

is  (512) 219-8020.  Our  website  address 

telephone  number 

Industry Background  

The  life  sciences  industry  uses  bioassays  to  detect  the  presence  and  characteristics  of  certain  biochemicals,  proteins  or 
nucleic  acids  in  a  sample.  Drug  discovery,  genetic  analysis,  pharmacogenomics,  clinical  diagnostics  and  general  biomedical 
research all use bioassays. For example, bioassays can be used to:  

•

•

•

•

  measure  the  presence  and  quantity  of  substances  such  as  infectious  agents,  antigens  for  histocompatibility,  hormones,
cancer markers and other proteins in a patient’s blood, other body fluid or tissue to assist physicians in diagnosing, treating
or monitoring disease conditions;

  detect genetic variations, such as single nucleotide polymorphisms or genetic mutations present in inherited diseases;

  measure the response to a compound or dosage by measuring cellular activity for drug discovery and development; and

  assist  physicians  in  prescribing  the  appropriate  tailored  drug  therapy  based  on  the  patient’s  unique  genetic  makeup,  a 

process known as pharmacogenetics. 

The  life  sciences  customer  can  purchase  bioassays  in  the  form  of  complete  off-the-shelf  kits,  develop  them  internally  or 
utilize a customized service to meet their specific needs. Although it is important to note that xMAP technology is relevant to a 
subset of the total life sciences market, based on external market research data, we believe the total global market for tools and 
consumables  used  in  drug  discovery  and  development,  clinical  diagnostics  and  biomedical  research  represented  a  market  of 
approximately $45 billion in end user sales in 2008, growing at an estimated 6% annually.  

2

                                   
   
The table below briefly describes the key bioassay technologies in the life sciences industry:  

KEY TECHNOLOGIES

DESCRIPTION

MARKETS SERVED

BioChips/Microarrays  

Automated Immunoassays  

Gels and blots  

PCR methods  

High-density arrays of DNA fragments 
or proteins attached to a flat glass or 
silicon surface 

Automated test tube-based instruments 
used for detecting antibodies, proteins 
and other analytes 

Biomedical research and select clinical 
diagnostics

Clinical diagnostics

Physical separation of molecules or 
analytes for visualization 

Clinical diagnostics and biomedical 
research

Tests which use polymerase chain 
reaction (PCR) technology to test DNA 
and ribonucleic acid (RNA) 

Nucleic acid testing in clinical 
diagnostics and biomedical research

Microfluidics chips  

Miniaturized liquid handling system on
a chip 

Biomedical research

Microtiter-plate based assays  

Genotyping technologies  

Gene expression technologies  

Plastic trays with discrete wells in 
which different types of assays are 
performed, usually Enzyme-Linked 
Immuno-Sorbent Assay (ELISA) tests 

DNA primers or probes designed to 
identify small differences between 
DNA targets using methods such as 
primer extension assays, ligation assays, 
cleavage assays or hybridization assays, 
sequencing and others 

DNA primers or probes designed to 
measure the degree of transcriptional 
activity of a specific gene, indicating 
how active the cells are in making the 
protein encoded by that gene 

Drug discovery, clinical diagnostics and 
biomedical research

Drug discovery, clinical diagnostics and 
biomedical research

Drug discovery, clinical diagnostics and 
biomedical research

Based on external market research data and our own internal estimates, we believe the potential life sciences market directly 
addressed  by  our  xMAP  technology  was  approximately  $2.1  billion  in  2008  and  that  it  will  reach  $3.3 billion  by  2012.  In 
addition, we are also focused on other specialty market segments, including food safety/animal health, newborn screening and 
bio-defense/bio-threats. With only limited market penetration of our multiplexing xMAP technology thus far in the key market 
segments referenced above, we believe there remain significant growth opportunities for Luminex and our strategic partners in 
each of these markets.  

3

                                   
   
 
 
 
 
  
 
  
 
 
 
 
  
 
  
 
 
 
  
 
  
 
 
 
 
  
 
 
 
 
 
 
  
 
Our xMAP Technology  

Our  xMAP  technology  combines  existing  biological  testing  techniques  with  advanced  digital  signal  processing  and 
proprietary software. With our technology, discrete bioassays are performed on the surface of color-coded microspheres. These 
microspheres  are  read  in  a  compact  analyzer  that  utilizes  lasers  and  high-speed  digital  signal  processing  to  simultaneously 
identify the bioassay and measure the individual assay results. The key features of xMAP technology include the following:  

•

  Multi-analyte/multi-format 

  xMAP technology has been designed to simultaneously perform up to 500 distinct bioassays in a single tube or well of a
microtiter  plate  using  only  a  small  amount  of  sample.  Moreover,  unlike  most  existing  technologies  that  are  dedicated  to
only one type of bioassay, xMAP can perform multiple types of assays including enzymatic, genetic and immunologic tests
on the same instrumentation platform. 

•

  Flexibility/scalability 

  xMAP  technology  allows  flexibility  in  customizing  test  panels.  Panels  can  be  modified  to  include  new  bioassays  in  the
same tube by adding additional microsphere sets. It is also scalable, meaning that there is no change in the manufacturing
process and only minimal changes to the required labor to produce a small or large number of microsphere-based tests.

•

  Both protein and nucleic acid applications on a single platform

  xMAP technology has an advantage due to its ability to analyze both proteins and nucleic acids. This allows customers to
utilize a single platform to evaluate samples across more biological parameters and generate a more complete assessment of
these samples. Alternative technologies are restricted to either proteins or nucleic acid, requiring customers to use two or
more technologies from other vendors to get the same information. 

•

  High throughput 

  Our  technology  can  perform  up  to  500  tests  in  a  single  well  permitting  up  to  96,000  unattended  tests  to  be  detected  in
approximately an hour with only a small amount of sample. Rapid sample analysis permits efficient use for high-throughput 
applications. 

•

  Ease of use 

  Most xMAP bioassays are simple to perform. A test sample is added to a solution containing microspheres that have been
coated with reagents. The solution is then processed through our xMAP technology system which incorporates proprietary
software to automate data acquisition and analysis in real-time.

•

  Cost effective 

  By performing multiple assays at one time, xMAP technology is designed to be cost effective for customers compared to
competitive techniques such as enzyme-linked immunosorbent assay (ELISA) or Real-time PCR. By analyzing only those 
assays in which a customer is interested, xMAP is also more cost effective than most competing microarray technologies. In
addition, microsphere-based bioassays are inexpensive compared to other technologies such as biochips. 

Polystyrene microspheres, approximately 5.6 microns in diameter, are a fundamental component of the xMAP technology. 
We purchase and manufacture microspheres and, in a proprietary process, dye them with varying intensities of proprietary dyes 
to achieve up to 500 distinct colors. The specific dye proportions permit each color-coded microsphere to be readily identified 
based on its distinctive fluorescent signature. Our customers create bioassays by attaching different biochemical reactants to each 
distinctly colored microsphere set. These  unique reactants  bind, or capture, specific substances present in  the  test sample. The 
microsphere sets can then be combined in test panels as required by the user, with a maximum of 500 tests per panel. Customers 
can order either standard microspheres or magnetic microspheres.  

4  

                                   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
To  perform  a  bioassay  using  xMAP  technology,  a  researcher  attaches  biochemicals,  or  reagents,  to  one  or  more  sets  of 
color-coded microspheres, which are then mixed with a test sample. This mixture is injected into the xMAP analyzer, where the 
microspheres pass single-file in a fluid stream through two laser beams. The first laser excites the internal dyes that are used to 
identify the color of the microsphere and the test being performed on the surface of the microsphere. The second laser excites a 
fluorescent dye captured on the surface of the microspheres that is used to quantify the result of the bioassay taking place. Our 
proprietary optics, digital signal processors and software record the fluorescent signature of each microsphere and compare the 
results to the known identity of that color-coded microsphere set. The results are analyzed and displayed in real-time with data 
stored on the computer database for reference, evaluation and analysis.  

xTAG®  technology developed  by  the assay  segment  consists of several components including multiplexed PCR or target 
identification primers, DNA Tags, xMAP microspheres, and data analysis software. xTAG technology permits the development 
of  molecular  diagnostic  assays  for  clinical  use  by  hospital  and  reference  laboratories.  xTAG  technology  has  been  applied,  in 
particular, to human genetic assays, pharmacogenetic assays, and infectious disease assays.  

We have an active product development pipeline of both instrument systems and assays. Our new instrument, FLEXMAP 
3D® was market released in June 2009 to complement our current instrument offerings. The FLEXMAP 3D system has twice the 
throughput of our LX 200 instrument and will detect, via multiplexing, up to 500 distinct biomarkers simultaneously in a single 
assay. This is a five fold increase in multiplexing capability over our LX200 instrument. The FLEXMAP 3D system, with these 
enhanced capabilities, will support our market expansion into new testing segments in both research and clinical testing markets 
in which high-throughput and/or high-multiplexing are key customer requirements.  

In addition to FLEXMAP 3D, we have a new instrument platform under development we refer to internally as MagPix™. 
Market  release  of  the  MagPix  is  expected  in  the  latter  half  of  2010.  MagPix  is  an  innovative  technology  platform  using  our 
proprietary  xMAP  magnetic  microspheres.  By  virtue  of  its  small  size  and  ease  of  use,  we  believe  MagPix  will  enhance  the 
adoption  of  our  xMAP  technology  in  our  existing  markets  and  allow  us  to  expand  xMAP  into  emerging  markets  including 
research, clinical and bio-threat testing segments with lower throughput and lower multiplexing requirements, but with increased
focus on capital cost considerations.  

We  have multiple  assay development activities ongoing in  the  assay segment.  The  assay segment has assay development 
programs focused in the areas of human genetics, pharmacogenetics, infectious disease, newborn screening, agricultural testing, 
and bio-threat. In 2010, we have plans to submit certain assay products to regulatory authorities for clearance in order to comply 
with established guidelines across the jurisdictions in which we participate.  

Business Strategy  

Our primary goal continues to be the establishment of Luminex as an industry leader and xMAP technology as the industry 
standard for  performing  bioassays  by transforming Luminex from  a technology-based  company to a  market-driven,  customer-
focused company. To achieve this goal, we have implemented and are pursuing the following strategies:  

•

  Focus on key market segments 

  We have identified the following key market segments: (i) life sciences research profile oriented screening and secondary
screening, (ii) life sciences research RNA profiling and transcriptional screening, (iii) genetic molecular infectious disease
testing,  and  (iv) immunodiagnostics.  In  addition  to  the  segments  listed  above,  we  have  identified  other  potential  market
opportunities in the applied markets such as bio-defense, or bio-threat testing, and food safety and animal health testing. We 
will continue to employ both a partnership driven business model focused on selected key segments and a product driven
business model in other key segments, working with distributors.

  We  will  continue  to  focus  our  commercialization  efforts  through  strategic  partners  on  large  sectors  of  the  life  sciences
industry  where  Luminex  believes  it  has  distinct  competitive  advantages  over  existing  and  emerging  technologies  and
approaches. We define strategic partners as companies in the life sciences industry that either develop and distribute assays
and  tests  on  xMAP  technology  or  may  only  distribute  our  xMAP  technology  based  systems  and  consumables.  With  our
partners’  support,  we  have targeted  major  pharmaceutical  companies, large clinical  laboratories, research  institutions  and
major medical institutions for our principal marketing efforts. We believe these customers provide the greatest opportunity
for  maximizing  the  use  of  xMAP  based  products  and  continued  adoption  by  these  industry  leaders  will  promote  wider
market acceptance of our xMAP technology. 

5

                                   
   
 
 
 
 
•

  Continue to develop strategic partnerships focused on our key market segments

  Currently,  39  of  our  approximately  68  strategic  partners  have  developed  reagent-based  products  utilizing  the  Luminex 
platform and are submitting royalties. We also have strategic partners who distribute Luminex products. During 2009, the
39  strategic  partners  who  have  commercialized  reagent-based  products  accounted  for  approximately  58%  of  our  total
revenue  and all  of  our  strategic  partners  represented  approximately  77%  of  our  total  revenue.  We  intend  to  broaden  and
accelerate  market  acceptance  of  xMAP  technology  through  development,  marketing  and  distribution  partnerships  with
leaders  in the life sciences industry.  By leveraging our strategic  partners’  market positions and utilizing  their distribution 
channels  and marketing infrastructure, we believe  we can  continue to expand  our installed  instrument base. Furthermore,
our  partners’  investments  in  research  and  development  for  xMAP  applications  provide  Luminex  users  with  more  menu
options than we can presently generate ourselves. 

•

  Develop and deliver market-leading assay products 

  We  are  focused  on  maximizing  the  value  we  provide  our  stockholders,  partners  and  end  user  customers  by  developing
internally  and  co-developing  with  partners  content  applications  based  on  customers’  needs  in  key  market  segments.  We 
believe  that  by  enhancing  both  our  partner  driven  model  and  our  direct  efforts  with  the  delivery  of  value-added  assay 
content,  Luminex  should  be  able  to  gain  greater  control  over  product  development,  market  penetration  and
commercialization. 

•

  Develop next generation products

  Our research and development group  is pursuing projects  such as the development of consumables, automation, software
and  the  expansion  and  enhancement  of  our  multiplexing  capabilities  to  advance  our  xMAP  technology  and  its  market
acceptance. We are also collaborating with industry participants, biomedical research institutions and government entities to
develop  additional xMAP products.  We also continuously consider  other  adjacent  markets  where  our platform and assay
offerings  would  be  beneficial.  We  believe  that  our  design,  development,  and  manufacturing  capabilities  and  FDA
compliance track record provide us a competitive advantage over our competitors, relating to the commercialization of both
multiplex testing platforms and assay products. 

•

  Opportunistically pursue acquisitions that could accelerate these strategies

  We  have  developed  analytical  tools  and  an  evaluation  template  to  assess  potential  acquisition  targets  to  accelerate  our
business strategies in the key markets described above. This approach led to the acquisition of Tm Bioscience in 2007. We
actively  evaluate  opportunities  to  enhance  our  capabilities  or  our  access  to  markets  or  technologies,  or  provide  us  other
advantages in executing our business strategies in our key markets. 

Products  

Technology Segment  

Instruments  

Luminex®  100™ and Luminex® 200™.  The  Luminex  100 and 200 are compact  analyzers that integrate fluidics, optics 
and digital signal processing to perform up to 100 bioassays simultaneously in a single tube or well of a microtiter plate using 
only  a  small  amount  of  sample.  By  combining  small  diode  lasers  with  digital  signal  processors  and  microcontrollers,  these 
systems  perform  rapid,  multi-analyte  profiles  under  the  control  of  a  Windows®-based  personal  computer  and  our  proprietary 
software.  

We  also  offer  two  peripheral  components  for  the  Luminex  systems  —  the  Luminex®  XYP™  (XY  Platform)  and  the 
Luminex® SD™ (Luminex Sheath Delivery System). The XY Platform complements the Luminex systems by automating the 
sequential positioning of each well of a microtiter plate, permitting up to 9,600 unattended tests per plate to be performed in less 
than an hour. The Luminex SD is a pressurized, external pump delivery system that enhances the delivery of sheath fluid to the 
Luminex systems by pumping sheath fluid from an external bulk reservoir, enabling the Luminex systems to operate for up to 24 
hours without switching to a new reservoir of sheath fluid.  

6

                                   
   
 
 
 
 
 
 
 
 
 
 
 
FLEXMAP 3D®. The FLEXMAP 3D system is intended for use as a general laboratory instrument in markets, including 
but not limited to, life science research and diagnostics. This device is designed for use with xMAP technology and assay kits 
available  through  Luminex  and  Luminex-partner  companies.  The  FLEXMAP  3D  system,  in  combination  with  xMAP 
technology,  can  simultaneously  measure  up  to  500  analytes  from  a  single  sample.  The  FLEXMAP  3D  is  Luminex’s  newest 
instrument and offers increased speed and enhanced ease-of-use and serviceability.  

Total  instrument  revenue  for  2009,  2008,  and  2007  was  $30.7 million,  $28.1 million,  and  $24.4  million,  respectively;  or 
25%, 27%, and 33% of total revenue, respectively. See Item 7 “Management’s Discussion and Analysis of Financial Condition 
and Results of Operations” and Item 8 “Financial Statements and Supplementary Data” for a detailed discussion of our financial 
position and results of operations by segment.  

Consumables  

MicroPlex®  Microspheres.  Our  xMAP  Systems  use  polystyrene  microspheres  that  are  approximately  5.6  microns  in 
diameter. We dye the microspheres in sets with varying intensities of a red and a near infrared dye to achieve up to 500 distinct 
color  sets.  Each  microsphere  can  carry  the  reagents  of  an  enzymatic,  genetic  or  immunologic  bioassay.  In  addition  to 
microspheres,  consumables  from  Luminex  also  include  sheath  fluid.  Additional  consumables,  for  which  Luminex  receives  a 
royalty, in the form of reagent kits are developed and distributed by our partners.  

MagPlex®  Microspheres.  These  microspheres  feature  super-paramagnetic  properties  that  make  them  ideal  for  running 
automated xMAP-based assays. These microspheres can be moved or held in place by a magnetic field. Many automated sample 
preparation systems utilize magnetic properties to automate the sample preparation steps in an assay. Automating sample testing 
using MagPlex microspheres on a robotic sample preparation system minimizes hands-on technician time, improves precision, 
and streamlines workflow.  

xTAG®  Microspheres.  These  dyed  microspheres  are  linked  to  a  set  of  100  proprietary  nucleic  acid  capture  sequences 
providing a  “universal  array”  for  DNA  and  RNA  work. They  are designed  for  conducting genotyping  and  other  nucleic  acid-
based experiments in the life sciences markets. When used in conjunction with our Luminex systems, the xTAG microspheres 
are designed to simplify the genotyping assay development process and increase assay flexibility. The xTAG microspheres may 
be  used  in  customized  end  user  identified  single  nucleotide  polymorphisms  (SNPs)  or  in  pre-defined  kits  developed  by  our 
strategic partners.  

SeroMAP™  Microspheres.  These  100  distinct  sets  of  microspheres  are  designed  for  specific  protein  based  serological 

applications. Certain Luminex partners use this product for enriched sensitivity in serum-based assays.  

Calibration and Control Microspheres. Calibration microspheres are microspheres of known fluorescent light intensities 
used  to  calibrate  the  settings  for  the  classification  and  reporter  channel  for  the  Luminex  systems.  Control  microspheres  are 
microspheres that are used to verify the calibration and optical integrity for both the classification and reporter channels for the 
Luminex 100, 200 and FLEXMAP 3D systems.  

Total consumable revenue for the years ended December 31, 2009, 2008, and 2007 was $28.4 million, $31.7 million, and 
$19.2 million, respectively; or 24%, 30%, and 26% of total revenue, respectively. The decrease in consumables as a percentage 
of total revenue is primarily attributable to the decrease in the dollar amount of bulk purchases by our two largest customers due 
to the varying consumable needs during the regulatory clearance and commercialization phases of development of our partners’
products  and  the  economic  environment.  Additionally,  our  partners  reported  approximately  $282 million,  $238 million,  and 
$170 million  of  royalty  bearing  consumable  sales  during  2009,  2008  and  2007,  respectively;  resulting  in  $18.3 million, 
$14.9 million, and $10.2 million of royalty revenue for the years ended December 31, 2009, 2008 and 2007, respectively or 15%, 
14%,  and  14%  of  total  revenue,  respectively.  See  Item 7  “Management’s Discussion  and  Analysis of Financial Condition and 
Results  of  Operations”  and  Item 8  “Financial  Statements  and  Supplementary  Data”  for  a  detailed  discussion  of  our  financial 
position and results of operations by segment.  

7

                                   
   
Software  

xPONENT®.  This software enhances both  ease-of-use  and automation capabilities  expanding  xMAP functionality  in  our 
core  market  segments.  Customer-centric  development  and  extensive  field  testing  with  customers  has  resulted  in  a  user 
experience which  is a significant step forward  in the  market place.  The software suite incorporates  important new features all 
designed to  simplify laboratory  workflow and  increase  productivity. New features  include  enhanced security  (21  CFR  Part 11 
compliance  and  electronic  signatures),  integration  capabilities  that  allow  users  to  transmit  and  receive  data  from  Laboratory 
Information  Systems  (LIS/LIMS),  integration  with  the  most  popular  automated  sample  preparation  systems,  the  ability  to  run 
magnetic  bead  applications  and  touch-screen  capability.  xPONENT  is  sold  on  new  Luminex  100,  200  and  FLEXMAP  3D 
systems and is available as an upgrade to the existing Luminex 100 and 200 systems in the marketplace. Sales of this product 
during 2009 did not represent a material component of our revenue.  

Assay Segment  

Product Families  

A  product  family  consists  of  two  or  more  assay  products  which  are  focused  on  similar  or  related  markets.  Each  assay 
consists of a combination of chemical and biological reagents and our proprietary bead technology used to perform diagnostic 
and research assays on samples. As of February 23, 2010 the following product families are commercially available:  

MicroRNA Family  

The FlexmiR® family of Research Use Only (RUO) kits is used by our customers to study the levels of microRNA targets 
in a variety of cells or tissues from different species. MicroRNA is of interest in a wide variety of applications including cancer 
and numerous other diseases.  

Respiratory Viral Family  

This family of products includes the xTAG® Respiratory Viral Panel, as well as xTAG® RVP FAST, a newer version of the 
original RVP assay. These in vitro diagnostic (IVD) products enable our laboratory end users to identify the causative agent for 
respiratory infections, a major cause of illness and mortality globally, for their physicians and patients.  

Cystic Fibrosis Family  

These FDA-cleared and Conformité Européenne (CE) marked IVD kits include the first-ever FDA-cleared IVD for cystic 
fibrosis  genotyping.  Current  recommendations  by  the  American  College  of  Medical  Genetics  (ACMG) and  the  American 
College  of  Obstetricians  and  Gynecologists  (ACOG) include  screening  for  23  mutations  in  the  cystic  fibrosis  transmembrane 
conductance regulator (CFTR) gene. The xTAG® Cystic Fibrosis Kits screen for these mutations in addition to a variety of other 
important cystic fibrosis (CF) mutations commonly found in the ethnically diverse North American and European populations. 
These kits are typically used for screening newborns and for diagnosing adult carriers of the CF gene.  

Personalized Medicine Products Family  

This  product  family  includes  three  assays  used  to  determine  the  drug  metabolism  status  of  individuals  for  specific 
medications.  All three  products include genotyping of genes encoding different  cytochrome  P450 drug metabolizing enzymes. 
This type of information is typically used to determine if a patient will need a lower or higher dose of a specific drug, or whether 
they  should  be  switched  to  a  different  medication  altogether.  These  three  assays  are  currently  Investigational  Use  Only 
(IUO) assays.  

8

                                   
   
Specialty Products Family  

This  family  of  products  includes  one  IVD  product  and  two  investigational  assays.  These  products  are  targeted  towards 

specialty, niche markets.  

In  addition  to  the  commercially  available  assays,  we  develop  custom  reagents  for  certain  of  our  partners.  Total  assay 
revenue  for  the  years  ended  December 31,  2009,  2008,  and  2007  was  $31.1  million,  $18.7 million,  and  $11.3 million, 
respectively; or 26%, 18%, and 15% of total revenue, respectively. The increase in assay revenue as a percentage of total revenue 
is primarily attributable to the acquisition of LMD. See Item 7 “Management’s Discussion and Analysis of Financial Condition 
and Results of Operations” and Item 8 “Financial Statements and Supplementary Data” for a detailed discussion of our financial 
position and results of operations by segment.  

Sales and Marketing  

Our sales  and marketing strategy is to expand the installed  base and utilization of xMAP technology. We are focused on 
generating recurring revenues from royalties on bioassay kits and testing services developed or performed by others that use our 
technology, as well as the sale of Luminex-developed assays, microspheres and other consumables. We have two key elements 
of our sales and marketing strategy. The first is our allegiance to Luminex’s historic strategic partner program with life sciences 
companies  that  develop  applications  or  perform  testing  using  our  technology  platforms  and  distribute  our  systems  to  their 
customers. The second is our dedication to marketing the assays developed by the assay segment through our strategic partners 
or directly to end users in segments where our partners do not participate.  

We continue to use strategic partners as our primary distribution channel, and we will continue to pursue new partnerships 
focusing  on  partners  with  market  presence  in  our  key  segments  described  above.  Some  of  our  strategic  partners  develop 
application-specific  bioassay  kits  for  use  on  our  xMAP  platform  that  they,  in  turn,  sell  to  their  customers  thereby  generating 
royalties for  us.  Certain  strategic partners  also  perform testing  services  for  third  parties using our technology  also resulting  in 
royalties for us. Other strategic partners also buy our products, including xMAP Luminex systems and consumables, or xTAG 
test kits, and then resell those products to their customers. As of December 31, 2009, we had approximately 68 strategic partners, 
compared  to  approximately  60  strategic  partners  as  of  December 31,  2008.  During  2009,  39  of  these  strategic  partners  had 
released commercialized products utilizing the Luminex platform and were submitting royalties. Of these 39 strategic partners 
with  commercialized  products,  18  companies  principally  serve  the  clinical  diagnostics  market  and  21  companies  principally 
serve the life science research market. Revenues through these commercialized, royalty-submitting, strategic partners constituted 
58%  of  our  revenues  for  2009.  We  also  believe  our  strategic  partners  provide  us  with  complementary  capabilities  in  product 
development, regulatory expertise and sales and marketing. By leveraging our strategic partners’ bioassay testing competencies, 
customer relationships and distribution channels, we believe that we can continue to achieve measurable market penetration and 
technology adoption.  

We  also serve as the  original  equipment manufacturer (OEM) for certain  strategic partners  that  choose  to sell  our xMAP 

technology as an embedded system under their own branding and marketing efforts.  

Customers  

In  2009,  2008  and  2007,  two  customers  each  accounted  for  more  than  10%  of  our  total  revenues.  One  Lambda,  Inc. 
accounted  for  15%,  19%,  and  15%  of  our  total  revenues  in  2009,  2008  and  2007,  respectively.  Bio-Rad  Laboratories,  Inc. 
accounted for 11%, 17%, and 20% of our total revenues in 2009, 2008 and 2007, respectively. No other customer accounted for 
more  than 10%  of  our  total revenues in  2009,  2008 or  2007. The  loss  of  either  one  of these  customers could  have a  material 
adverse effect on our business, financial condition and results of operation.  

One Lambda, Inc. accounted for 21%, 24% and 18% of the Company’s total technology segment revenues in 2009, 2008 
and  2007,  respectively.  Bio-Rad  Laboratories,  Inc.  accounted  for  16%,  21%  and  24%  of  the  Company’s  total  technology 
segment  revenues  in  2009,  2008  and  2007,  respectively.  Fisher  Scientific  accounted  for  31%,  21%  and  less  than  10%  of  the 
Company’s  total  assay  segment  revenues  in  2009,  2008  and  2007,  respectively.  Abbott  Laboratories  accounted  for  21%,  less 
than 10%, and less than 10% of the Company’s total assay segment revenues in 2009, 2008 and 2007, respectively. Genzyme 
Genetics  accounted  for  15%,  27%,  and  33%  of  the  Company’s  total  assay  segment  revenues  in  2009,  2008  and  2007, 
respectively. LabCorp accounted for less than 10%, less than 10%, and 13% of the Company’s total assay segment revenues in 
2009, 2008 and 2007, respectively. No other customer accounted for more than 10% of total segment revenues in 2009, 2008 or 
2007.  

9  

                                   
   
International Operations  

We currently sell our products to a number of customers outside the United States, primarily including customers in other 
areas  of  North  America,  Europe  and  Asia-Pacific.  For  the  annual  periods  ended  December 31,  2009,  2008,  and  2007,  foreign 
sales  to  customers  totaled  $22.8 million,  $15.0 million,  and  $11.4 million,  respectively,  representing  19%,  14%,  and  15%, 
respectively, of our total revenues for such periods. We have foreign subsidiaries in the Netherlands, the People’s Republic of 
China  and  Japan  which  increase  our  international  support,  service  and  marketing  capabilities.  Our  foreign  subsidiaries  are  a 
direct  and  integral component of  the  U.S.  entity’s  operations  and  their  efforts  support  the  sales made  by  our  North  American 
entities. Sales to territories outside of the U.S. are primarily denominated in U.S. dollars. We believe that our activities in some 
countries outside the U.S. involve greater risk than our domestic business due to the foreign economic conditions, exchange rate 
fluctuations,  local  commercial  and  economic  policies  and  political  uncertainties.  See  Note  17  to  our  Consolidated  Financial 
Statements.  

Technical Operations  

Our  Technical  Operations  Group  provides technical support  to our  customers,  our  strategic  partners  and  their  customers. 
Most of our technical operations personnel have experience as biologists, biochemists, or electrical engineers and have extensive 
experience in academic, industrial and commercial settings. Cross training is a major focus, empowering group members to solve 
problems outside their primary assignment.  

Remote Support  

Our  technical  support services  department assists users primarily  through  a  toll-free  hotline, internet  interface and e-mail 
communications. We deliver “24/7” remote technical support with our staff based at our Austin location, our Toronto location, 
and in our European, Chinese, and Japanese subsidiaries to better serve our customer base. Personnel assist our strategic partners 
and  customers  with  product  orders,  software,  hardware,  system  implementation  and  development  of  their  bioassays.  A 
comprehensive  software  and  database  system  is  utilized  to  track  customer  interactions,  follow  trends  and  measure  utilization. 
The information is categorized and presented to management for regular review.  

Training  

Through  our  training  group,  we  offer  comprehensive  programs  in  basic  system  training,  advanced  assay  development, 
instrument  field  service  and  technical  support  functions.  A  significant  part  of  our  training  material  is  now  web-based  and 
available online. For larger customers who have many users, such as our strategic partners, training may be performed on-site at 
their locations.  

Field Support  

We currently have field service and field application  personnel based across North America, Europe, China and Japan in 
areas of our more significant system concentration. We intend to place additional field service personnel and pursue third-party 
service  provider agreements through our certified  service professional program, as required, in order to ensure responsive and 
cost-effective support of our customers worldwide. In addition, several of our strategic partners provide their own field service 
and field application support. As we continue to expand our installed base, we believe a strong, reliable, efficient field support 
organization is crucial to building a high level of customer satisfaction.  

10

                                   
   
Research and Development  

Our  research  and  development  groups  seek  to  advance  the  capabilities  of  xMAP  technology  to  further  penetrate  the  life 
sciences  and  diagnostics  industry  to  increase  utilization  of  our  systems.  In  addition,  we  collaborate  with  other  companies, 
academic institutions and our customers to increase the breadth of xMAP applications. Our research and development expense 
for the years ended December 31, 2009, 2008, and 2007, was $20.8 million, $18.6 million and $15.4 million, respectively. Our 
current research and development projects include:  

•

  New product development 

  Our  research  and  development  teams,  including  the  assay  segment,  and  marketing  team  are  working  closely  with  both
internal and external groups to design and develop products that will expand capabilities of the xMAP-based technologies. 
We  believe  that  these  efforts  will  continue  to  result  in  unique  products.  These  products  will  include  instrumentation,
services, software and consumables including assays.

•

  Instrument development 

  Our  engineering  group  responsible  for  the  design  of  our  xMAP  instruments  leverages  proprietary  electrical,  optical  and
digital signal processing technologies to achieve high performance and reliability. This methodology enabled the recently
released FLEXMAP 3D® instrument to double throughput, multiplex up to 500 analytes, enhance assay limit of detection,
and greatly extend the usable dynamic range. 

  To further market penetration, we are now engaged in the development of an instrument line that maintains the top features
of our existing products, at a greatly reduced sales and manufacturing cost. Simultaneously, a highly efficient subset of the
engineering  team  is  engaged  in  the  focused  research  necessary to extend our  intellectual property position,  and  keep  our
products innovative for many years to come. 

•

  Assay development 

  Our  assay  segment,  consisting  of  LBG  and  LMD, develops new assay products  that  include  both  nucleic  acid-based  and 
protein-based assays. These assays include immunoassays and molecular diagnostic assays for the diagnostics industry, and
nucleic  acid-based  and  protein-based  assays  for  the  life  science  research  and  agricultural  science  markets.  All  assay
applications  make  use  of  our  xMAP  technology  and  our  strength  in  multiplex  technology.  Our  assay  research  and
development  is  intended  to  increase  the  penetration  of  our  xMAP  instruments  and  our  application  menu,  and  to  drive
growth in our high-margin assay businesses. 

•

  Consumable development 

  We continue to develop and enhance our existing consumable product line and support introduction of new product lines.

These new products include calibrators, controls and microspheres with additional performance characteristics. 

  Our current bead utilizes three common chemistries for the immobilization of assays on its surface. While these chemistries
are well accepted in the industry, it is desirable to expand our bead chemistry capability to enhance market penetration and
adoption. We continue to work on other surface chemistries to provide optimal performance in broader application areas.

•

  Software development 

  Our software research and development teams will continue to extend xPONENT instrument control and analysis software
capabilities.  xPONENT  software  provides  analysis  and  automation  interface  capabilities  as  well  as  control  functions  for
Luminex  instruments  like  the  FLEXMAP  3D  product.  New  versions  of  xPONENT  will  provide  sophisticated  data
regression  functionality  and  increased  productivity  through  better  instrument  utilization.  We  continue  to  develop
applications  like  xPONENT  QC-Reviewer  that  will  bridge  the  gap  between  the  instrument  control  software  and  the
Laboratory  Information  Systems  (LIS) to  provide  better  test  results  management  and  wider  use  of  Luminex  developed
assays. 

11

                                   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
•

  Automation 

  We collaborate with our strategic partners and others to provide automation solutions that will integrate our various xMAP
instruments  with  sample  handling  equipment  and  laboratory  information  systems  to  increase  bioassay  throughput  and
operational efficiencies and allow for walk-away capability. 

•

  Enhancing bioassay performance and operational efficiencies 

  Our  scientists  and  engineers  dedicate  efforts  to  further  enhance  xMAP  in  the  areas  of  assay  performance,  such  as
sensitivity, precision, reliability and operational efficiencies. We are actively collecting market and customer requirements
that will allow us to provide optimal features and benefits in current and future products.

Manufacturing  

We  have  approximately  29,000  square  feet  of  manufacturing  space  located  at  our  principal  executive  offices  in  Austin, 
Texas. In 2002, we completed the registration of our Quality Management System (QMS) to the ISO 9001:2000 standard, which 
is an internationally recognized standard for quality management systems. Subsequent audits by the registrar have been and will 
continue  to  be  carried  out  at  regular  intervals  to  ensure  we  are  maintaining  our  system  in  compliance  with  ISO  standards. 
Recertification is required every three years and we were successfully recertified as of February 23, 2007.  

In  July 2005,  we  completed  the  registration  of  our  QMS  to  the  ISO  13485:2003  Quality  Management  Standard  and  the 
Canadian Medical Devices Conformity Assessment System (CMDCAS) for Medical Devices. This standard  includes  a special 
set of requirements  specifically related to the supply of medical devices  and related services. Additionally, we manufacture to 
current  Good  Manufacturing  Practice  (cGMP)  requirements  and  our  QMS  is  implemented  in  accordance  with  FDA  Quality 
System Regulations. In August 2006, a Level II Quality System Inspection Technique (QSIT) contract inspection was conducted. 
The inspection is “closed” under 21 C.F.R. 20.64 (d) (3) and the Establishment Inspection Report No. 3002524000 provided in 
accordance  with  the Freedom of  Information  Act  (FOIA) and 21  C.F.R.  Part 20.  No  DSHS  form E-14  or  FDA  form  483  was 
issued.  

In addition, we have approximately 4,000 square feet of manufacturing space located in Toronto, Canada. This facility and 

the LMD QMS have been certified to the ISO 13485:2003 standard and registered under the CMDCAS.  

Instruments  

Contract  manufacturers  assemble  certain  components  of  our  xMAP  technology  systems.  The  remaining  assembly  and 
manufacturing of our systems are performed at our facility in Austin, Texas. The quality control and quality assurance protocols 
are all performed at our facility. Parts and component assemblies that comprise our xMAP technology system are obtained from 
a number of sources. We have identified alternate sources of supply for several of our strategic parts and component assemblies. 
Additionally, we have entered into supply agreements with most of our suppliers of strategic parts and component subassemblies 
to  help  ensure  component  availability,  and  flexible  purchasing  terms  with  respect  to  the  purchase  of  such  components.  As  of 
December 31, 2009, 6,767 Luminex systems have been sold since inception.  

Microspheres  

We manufacture as well as procure undyed, standard and magnetic carboxylated polystyrene microspheres. We synthesize 
our  dyes  and  manufacture  our  dyed  polystyrene  microspheres  using  a  proprietary  method in our  Austin,  Texas  manufacturing 
facility in large lots. We dye the microspheres with varying intensities of a red and a near infrared dye to produce our distinctly 
colored  microsphere  sets.  We  currently  purchase  polystyrene  microspheres  from  one  supplier,  in  accordance  with  a  supply 
agreement. We believe this agreement will help ensure microsphere availability and flexible purchasing terms with respect to the 
purchase of such microspheres. While we believe the microspheres will continue to be available from our supplier in quantities 
sufficient to meet our production needs, we believe our in-house manufacturing capabilities along with other potential suppliers 
would provide sufficient microspheres for us if given adequate lead-time to manufacture the microspheres to our specifications.  

12

                                   
   
 
 
 
 
 
Kits  

Contract manufacturers produce certain components of our xMAP-based developed reagents. The remaining assembly and 
manufacturing of our developed kits are performed at either our facility in Austin, Texas or Toronto, Canada. The quality control 
and quality assurance protocols are all performed at our facilities. Reagents and component assemblies that comprise our xMAP 
technology kits are obtained from a number of sources.  

Competition  

We  design  our  xMAP  technology  for  use  by  customers  across  the  various  segments  of  the  life  sciences  industry.  Our 
competition includes companies marketing conventional testing products based on established technologies such as ELISA, real-
time  PCR,  mass  spectrometry,  sequencing,  gels,  biochips  and  flow-based  technologies  as  well  as  companies  developing  their 
own advanced testing technologies.  

The pharmaceutical industry is a large market for the genomic, protein and high-throughput screening applications of the 
xMAP technology. In each application area, Luminex faces a different set of competitors. Genomic and protein testing can be 
performed  by  products  available  from  Affymetrix,  Inc.,  Life  Technologies  Corporation,  Becton,  Dickinson  and  Company, 
Illumina, Inc., Meso Scale Discovery, a division of Meso Scale Diagnostics LLC, and Sequenom, Inc., among others.  

Our  diagnostic  market  competitors  include  Abbott  Laboratories,  Beckman  Coulter,  Inc.,  Celera  Corporation,  Cepheid, 
Johnson  &  Johnson,  Roche  Diagnostics,  Siemens  Medical,  and  Hologic,  Inc.  among  others.  Some  of  these  companies  have 
technologies  that  can  perform  a  variety  of  established  assays.  Some  of  these  companies  also  offer  integrated  systems  and 
laboratory automation that are designed to meet the need for improved work efficiencies in the clinical laboratory.  

Competition within the academic biomedical research market is highly fragmented. There are hundreds of suppliers to this 
market including Amersham Pharmacia Biotech, a part of GE Healthcare, Life Technologies Corporation, and Becton, Dickinson 
and Company. Any company in this field is a potential competitor.  

Intellectual Property  

To  establish  and  protect  our  proprietary  technologies  and  products,  we  rely  on  a  combination  of  patent,  copyright, 
trademark  and  trade  secrets  laws  and  confidentiality  agreements.  We  have  filed  for  registration  or  obtained  registration  for 
trademarks used with our products and key technology.  

We have implemented a strategy designed to optimize our intellectual property rights. For core intellectual property, we are 
pursuing  patent  coverage  in  the  United  States  and  those  foreign  countries  that  correspond  to  the  majority  of  our  anticipated 
customer  base.  We  currently  own  89  issued  patents  in  the  United  States  and  foreign  jurisdictions,  including  five  in  each  of 
France, Germany and the United Kingdom, four in Japan and Canada, three in Italy, two each in India, Singapore and Australia 
and one in each of Hong Kong, Korea and Israel, all directed to various aspects and applications of our products and technology. 
In  addition,  our  patent  portfolio  includes  215  other  pending  patent  applications  in  the  United  States  and  their  corresponding 
international and  foreign counterparts in major industrial markets. We believe our  patents and pending  claims provide, or will 
provide, protection for systems and technologies that allow  “real time” multiplexed analytical techniques for the detection and 
quantification of many analytes from a single sample. We also hold a patent covering the precision-dyeing process that we use to 
dye our microspheres. We have been granted a patent on our “Zero Dead Time” sampling architecture, which uses digital over-
sampling to measure the area of a fluorescence pulse instead of “peak detection,” giving increased sensitivity with no lost events. 
Other issued patents and pending patent applications cover specific aspects and applications of our xMAP technology and on-
going molecular research. However, as a result of a procedural omission, we are unable to pursue a patent application in Japan 
corresponding  to  our  U.S.  patent  for  real-time  multiplexing  techniques.  We  also  have  patents  covering  key  aspects  of  xTAG 
technology utilized in our assay products.  

The  source code for our proprietary software  is protected  as a trade  secret and/or as  a  copyrighted work.  Aspects of this 

software also are covered by an issued patent.  

13

                                   
   
We also rely on trade secret protection of our intellectual property. We attempt to protect our trade secrets by entering into 
confidentiality  agreements  with  strategic  partners,  third  parties,  employees  and  consultants.  Our  employees  and  third-party 
consultants also sign agreements requiring that they assign to us their interests in inventions and original works of expression and 
any corresponding patents and copyrights arising from their work for us.  

Government Regulation  

Food and Drug Administration  

The Food and Drug Administration regulates medical devices pursuant to various statutes, namely the Federal Food, Drug 
and Cosmetic Act as amended and supplemented by the Medical Device Amendments of 1976, the Safe Medical Devices Act of 
1990,  the  Medical  Device  Amendments  of  1992,  the  FDA  Export  Reform  and  Enhancement  Act  of  1996,  the  FDA 
Modernization Act of 1997, the Public Health, Security and Bioterrorism Preparedness and Response Act of 2002, the Medical 
Device User Fee and Modernization Act of 2002, and the Project BioShield Act of 2004. Medical devices, as defined by statute, 
include  instruments,  machines,  in  vitro  reagents  or  other  similar  or  related  articles,  including  any  components,  parts,  or 
accessories  of  such  articles  that  are  intended  for  use  in  the  diagnosis  of  disease  or  other  condition  or  in  the  cure,  mitigation, 
treatment  or  prevention  of  disease;  or  are  intended  to  affect  the  structure  or  function  of  the  body  and  do  not  achieve  their 
intended purpose through chemical action or metabolization. The FDA classifies medical devices intended for human  use into 
three classes. For Class I devices, general controls (for example, labeling and good manufacturing practices) provide reasonable 
assurance  of  safety  and  effectiveness.  Class II  devices  are  products  for  which  general  controls  do  not  provide  reasonable 
assurance  of  safety  and  effectiveness  and  for  which  there  is  sufficient  information  to  establish  special  controls  (for  example, 
special control documents, guidelines and patient registries). Class III devices are products for which neither general nor special 
controls provide reasonable  assurance of safety and  effectiveness. Generally, Class III includes devices  that  support or sustain 
human  life,  are  for  uses  that  are  substantially  important  in  preventing  impairment  of  human  health,  are  used  as  a  stand  alone 
assay for patient screening or diagnosis of disease, or present a potential, unreasonable risk of illness or injury.  

We manufacture a version of the Luminex 100 and Luminex 200 — the Luminex 100 Integrated System (Luminex 100 IS) 
and the Luminex 200 Integrated System (Luminex 200 IS), respectively — for use with diagnostic assay kits that are available 
through our strategic partners. For FDA purposes, the Luminex 100 IS and Luminex 200 IS are IVD cleared and are considered a 
component of our partners’ kit products. Depending on the particular kit’s regulatory classification into Class I, II, or III and its 
intended use, kits manufactured by our strategic partners that are used in conjunction with our technology may be subject to FDA 
clearance or approval  before they  can  be  marketed and  sold. After incorporating the  Luminex 100 IS  or Luminex  200  IS into 
their  products,  our  strategic  partners  are  required  to  make  various  premarket  submissions  such  as  premarket  approval 
applications, premarket notifications and/or investigational device exemption applications to the FDA for their products and are 
required to comply with numerous requirements and restrictions prior to clearance or approval of the applications. There can be 
no assurance that the FDA will file, clear or approve our strategic partners’ submissions.  

We manufacture kit products that are intended for research use only (RUO) applications (not for diagnostic use) as well as 
kits  that  are  for  diagnostic  use  (currently  regulatory  classification  of  Class II)  in  our  Austin,  Texas  facility.  Additionally,  the 
assay  segment  manufactures  products  that  are  intended  for  RUO,  those  that  are  IVD  cleared  (Class II)  as  well  as  kits  and 
investigational use only (IUO) or clinical applications.  

In  December,  2007  we  submitted  to  the  FDA  our  request  for  510(k)  clearance  on  our  Luminex  100/200  Instrument.  On 
December 13, 2007 the FDA received our 510(k) #k073506 submission for the Luminex 100/200 IS System. On March 7, 2008, 
the instrument received FDA 510(k) clearance. All future diagnostic assay kits subject to FDA clearance may reference the 510
(k)  #k073506  for  the  instrument  in  their  respective  applications.  A  master  file  letter  from  Luminex  allowing  the  partner  to 
reference the file may be required.  

Our instruments use lasers to identify the bioassays and measure their results. Therefore, we are required to ensure that our 
products comply with FDA regulations pertaining to the performance of laser products. These regulations are intended to ensure 
the  safety  of  laser  products  by  establishing  standards  to  prevent  exposure  to  excess  levels  of  laser  radiation.  There  can  be  no 
assurance that the FDA will agree with our interpretation and implementation of these regulations.  

14

                                   
   
We, and our strategic partners, may be subject to periodic inspection by the FDA for, among other things, compliance with 
the FDA’s current good manufacturing practice regulations. These regulations, also known as the Quality System Regulations, 
govern  the  methods  used  in,  and  the  facilities  and  controls  used  for,  the  design,  manufacture,  packaging,  labeling,  servicing, 
installation and distribution of all finished medical devices intended for human use. Additionally, our strategic partners may be 
subject to other premarket and post market controls such as labeling, complaint handling, medical device reporting, corrections 
and  removals  reporting,  and  record  keeping  requirements.  If  the  FDA  has  evidence  demonstrating  that  a  company  is  not  in 
compliance  with  applicable  regulations,  it  can  detain  or  seize  products,  request  or,  in  certain  circumstances,  require  a  recall, 
impose operating restrictions, enjoin future violations, recommend criminal prosecution to the Department of Justice, and assess 
civil and criminal penalties against us, our officers, or our employees. Other regulatory agencies may have similar powers.  

Medical  device laws  and regulations are  also  in  effect  in  many  countries  outside  of the  United States.  These range  from 
comprehensive preapproval requirements for medical products to simpler requests for product data or certification. The number 
and scope  of these requirements  are  increasing. There can  be  no  assurance that  we, and  our strategic  partners, will  be  able  to 
obtain any approvals that may be required to market xMAP technology products outside the United States.  

The  assay  segment  produces  CE  marked  products  which  are  subject  to  a  number  of  different  European  Union 
(EU) Directives including but not limited to the In Vitro Diagnostic Devices Directive (98/79/EEC). CE marking of our products 
is currently by self declaration, not issued by a third party, based on the intended uses of our products. A product that is not CE 
marked is automatically considered to be non-compliant. The law is enforced through market surveillance by appointed national 
enforcement agencies. Imported products are checked for compliance at customs offices.  

The  State Food  and Drug Administration, P.R.  China  (SFDA) is  the  Government  regulation  authority  in  charge of safety 
management of drug, food, health food and cosmetics for the People’s Republic of China. In December 2007 we submitted the 
application for a certificate to combine both Luminex 100 and 200 into one product called Luminex System. This certificate is 
required for registration and approval to import our products into China. Luminex received the registration certificate from the 
People’s Republic of China for the Luminex 100 and Luminex 200 Systems on March 4, 2009.  

Failure  by  us,  or  our  strategic  partners,  to  comply  with  applicable  federal,  state  and  foreign  medical  product  laws  and 
regulations  would  likely  have  a  material  adverse  effect  on  our  business.  In  addition,  federal,  state  and  foreign  regulations 
regarding the manufacture and sale of medical devices and components of such devices are subject to future changes. We cannot 
predict what impact, if any, such changes might have on our business, but any such change could have a material impact.  

WEEE  

As part of the Council Directive 2002/26 of February 13, 2003, Waste Electrical and Electronic Equipment (WEEE), we are 
in compliance with the requirements, beginning on August 13, 2005, regarding the labeling and disposal of some of our products 
containing electronic devices in each of the EU member states where our regulated products are distributed. While we are taking 
steps to comply with the requirements of WEEE, we cannot be certain that we will comply with the implementation of WEEE in 
all EU member states.  

15  

                                   
   
European IVD Directive  

The EU’s regulation of in vitro medical devices is under the In Vitro Diagnostic Directive (IVDD) 98/79/EC of October 27, 

1998, as implemented in the EU member states.  

The principle behind the IVDD is that no in vitro device or accessory may be placed on the market or put into service unless 
it satisfies the essential requirements set forth in the IVDD. Devices considered to meet the essential requirements must bear the 
CE marking of conformity when they are placed on the market. The responsibility for placing the CE marking on the device lies 
with  the  manufacturer.  A  manufacturer  placing  devices  on  the  market  in  its  name  is  required  to  notify  its  national  competent 
authorities.  

Luminex  Corporation  has  declared  that  the  LX100  IS,  the  LX200  IS  and  the  FLEXMAP  3D  are  classified  as  a  self-
declaration  device  and  is  in  conformity  with  Article 1,  Article 9,  Annex  I  (Essential  Requirements),  and  Annex  III,  and  the 
additional  provisions of  IVDD  98/79/EC.  However,  there  can  be no  assurance that  the EU  member  states  will  agree  with  our 
interpretation and implementation of these regulations. As the European marketplace continues to be material to our operations, 
failure by us or our strategic partners to comply with the IVDD could have a material adverse effect on our business.  

Environmental  

We  are  subject  to  federal,  state  and  local  laws  and  regulations  relating  to  the  protection  of  human  health  and  the 
environment.  In  the  course  of  our  business,  we  are  involved  in  the  handling,  storage  and  disposal  of  certain  chemicals  and 
biohazards. The laws and regulations applicable to our operations include provisions that regulate the discharge of materials into 
the  environment.  Some  of  these  environmental  laws  and  regulations  impose  “strict  liability,”  rendering  a  party  liable  without 
regard to negligence or fault on the part of such party. Such environmental laws and regulations may expose us to liability for 
environmental  contamination,  including  remediation  costs,  natural  resource  damages  and  other  damages  as  a  result  of  the 
conduct of, or conditions caused by, us or others, or for acts that were in compliance with all applicable laws at the time such 
acts  were  performed.  In  addition,  where  contamination  may  be  present,  it  is  not  uncommon  for  neighboring  landowners  and 
other third parties to file claims for personal injury, property damage and recovery of response costs. Although it is our policy to 
use  generally  accepted  operating  and  disposal  practices  in  accordance  with  applicable  environmental  laws  and  regulations, 
hazardous substances or wastes may have been disposed or released on, under or from properties owned, leased or operated by us 
or  on,  under  or  from  other  locations  where  such  substances  or  wastes  have  been  taken  for  disposal.  These  properties  may  be 
subject  to  investigation,  remediation  and  monitoring  requirements  under  federal,  state  and  local  environmental  laws  and 
regulations.  We  believe  that  our operations  are  in  substantial  compliance  with  applicable  environmental  laws  and  regulations. 
However, failure to comply with these environmental laws and regulations may result in the imposition of administrative, civil 
and  criminal  penalties  or  other  liabilities.  We  do  not  believe  that  we  have  been  required  to  expend  material  amounts  in 
connection with our efforts to comply with environmental requirements or that compliance with such requirements will have a 
material  adverse  effect  upon  our  capital  expenditures,  results  of  operations  or  competitive  position.  Because  the  requirements 
imposed by such laws and regulations may frequently change and new environmental laws and regulations may be adopted, we 
are  unable  to  predict  the  cost  of  compliance  with  such  requirements  in  the  future,  or  the  effect  of  such  laws  on  our  capital 
expenditures,  results  of  operations  or  competitive  position.  Moreover,  the  modification  or  interpretation  of  existing 
environmental laws or regulations, the more vigorous enforcement of existing environmental laws or regulations, or the adoption 
of new environmental laws or regulations may also negatively impact our strategic partners, which in turn could have a material 
adverse effect on us and other similarly situated component companies.  

16  

                                   
   
Employees  

As  of  both  February 23,  2010  and  December 31,  2009,  we  had  a  total  of  437  employees  and  contract  employees,  as 
compared  with  384  as  of  December 31,  2008.  The  increase  from  2008  to  2009  is  mainly  due  to  personnel  added  related  to 
development, production, regulatory clearance, and quality control for our new instrument, MagPix, and our new bead products 
and assays, as well as our expansion into China and Japan. None of our employees  are represented by a  collective bargaining 
agreement, and we have not experienced any work stoppage. We believe that relations with our employees are good.  

Segments  

Financial information relating to our reportable segments for the years ended December 31, 2009, 2008, and 2007 can be 
found  in  Item 7  “Management’s  Discussion  and  Analysis  of  Financial  Condition  and  Results  of  Operations”  and  Item 8 
“Financial Statements and Supplementary Data”.  

Executive Officers of the Registrant as of February 25, 2010  

Name

Patrick J. Balthrop  
Michael F. Pintek  
Russell W. Bradley  
Jeremy Bridge-Cook, Ph.D  
Harriss T. Currie  
Gregory J. Gosch  
David S. Reiter  

Age

53 
41 
46 
41 
48 
47 
 43 

Position

President and Chief Executive Officer
Senior Vice President, Operations

  Vice President, Business Development and Strategic Planning

Senior Vice President, Assay Group

  Chief Financial Officer, Vice President, Finance and Treasurer
  Vice President, Luminex Bioscience Group
  Vice President, General Counsel and Corporate Secretary

Patrick J. Balthrop. Mr. Balthrop joined Luminex in May 2004 as President and Chief Executive Officer and has served as 
a  member  of  the  Board  of  Directors  since  September 2004.  He  served  as  president  of  Fisher  Healthcare,  a  Fisher  Scientific 
International company, a manufacturer and supplier of products and services principally to the scientific and laboratory markets 
from 2002 to May 2004. Prior to Fisher Scientific International, Mr. Balthrop served in a number of leadership positions for over 
20 years with Abbott Laboratories, primarily in  Abbott’s Diagnostics Division. Mr. Balthrop’s most recent positions  at Abbott 
were  as head of worldwide commercial diagnostics operations and as head of Abbott Vascular. Mr. Balthrop holds  an M.B.A. 
from the Kellogg Graduate School of Management of Northwestern University, and a B.S. in Biology from Spring Hill College.  

Michael  F.  Pintek.  Mr. Pintek  joined  Luminex  as  Senior  Vice  President  of  Operations  in  July  2009.  He  joined  Luminex 
from  Roche  Molecular  Systems,  Inc.,  a  subsidiary  of  Roche  Diagnostics  Corporation  where  he  held  several  positions  of 
increasing responsibility since 2001, most recently as Vice President and General Manager, Blood Screening at Roche. Prior to 
Roche  Molecular  Systems,  his  experience  includes  management  positions  with  Ventana  Medical  Systems  and  Abbott 
Laboratories’ Diagnostics Division. Mr. Pintek holds a B.S. in Business Administration from Central Michigan University.  

Russell  W. Bradley.  Mr. Bradley  joined  Luminex  in  May 2005  as Vice  President of  Business  Development  and  Strategic 
Planning. Previously, Mr. Bradley spent 17 years at Beckman Coulter Corp., a manufacturer of biomedical testing systems and 
products, where he served as the director of the Beckman Coulter CARES initiative, involved in Luminex’s clinical HIV/AIDS 
monitoring business in developing regions around the globe. During his tenure at Beckman Coulter, Mr. Bradley was involved in 
the  evaluation,  market  assessment  and  successful  commercial  launch  of  multiple  life  science  technologies  and  applications. 
Mr. Bradley holds a B.S. in Immunology and Biochemistry from Monash University, Melbourne, Australia.  

17

  
   
 
 
 
 
 
 
 
 
  
 
  
 
 
 
 
 
 
 
 
 
 
 
 
Jeremy  Bridge-Cook,  Ph.D.  Dr. Bridge-Cook  has  served  as  Senior  Vice  President,  Assay  Group  since  June 2009. 
Dr. Bridge Cook joined Luminex in March 2007 as Vice President of Luminex Molecular Diagnostics. Previously, Dr. Bridge-
Cook  served  as  senior  vice  president,  corporate  development  of  Tm  Bioscience.  Dr. Bridge-Cook  joined  Tm  Bioscience  in 
July 2000 as director  of  business development and served in various capacities  thereafter, including vice president of business 
development, vice president of marketing and business development, and finally senior vice president, corporate development. 
Prior  to  joining  Tm,  Dr. Bridge-Cook  worked  for  three  years  as  an  investment  analyst  at  MDS  Capital  Corp.  and  University
Medical Discoveries Inc. Dr. Bridge-Cook has a Ph.D. in Immunology from the University of Toronto.  

Harriss T. Currie. Mr. Currie has served as Vice President, Finance, Treasurer and Chief Financial Officer since October of 
2002. Since joining Luminex in November of 1998, Mr. Currie previously served in the capacities of Controller, Treasurer and 
Acting  Chief  Financial  Officer.  Prior  to  joining  us,  he  was  employed  as  the  chief  financial  officer,  secretary  and  treasurer  of 
SpectraCell  Laboratories  from  1993  to  1998  where  he  also  served  as  vice  president  of  finance  for  two  subsidiary  companies. 
Mr. Currie earned his B.B.A. from Southwestern University and his M.B.A. in Finance and Marketing from The University of 
Texas at Austin. Prior to returning to graduate school for his M.B.A., Mr. Currie was a certified public accountant with Deloitte 
& Touche LLP.  

Gregory  J.  Gosch.  Mr. Gosch  joined  Luminex  in  October 2004,  and  currently  serves  as  Vice  President,  Luminex 
Bioscience Group. Since joining Luminex, Mr. Gosch previously served in the capacity of Vice President, Marketing and Sales. 
Previously,  he  served  in  commercial  management  positions  at  other  life  sciences  companies  including  Nanogen  Inc.,  a 
manufacturer  of  diagnostic  testing  products,  Chiron  Corporation  and  Bio-Rad  Laboratories,  Inc.  Mr. Gosch  holds  an  M.B.A. 
from the Carlson School of Management, a Masters of Health Care Administration from the School of Public Health, both of the 
University of Minnesota, and a B.A. in Molecular, Cellular and Developmental Biology from the University of Colorado.  

David S. Reiter. Mr. Reiter joined Luminex as Vice President, General Counsel and Corporate Secretary in October 2003. 
Prior to becoming General Counsel, Mr. Reiter was in private practice with the firm of Phillips & Reiter, PLLC, which provides 
outsourced general counsel services for technology companies. Before co-founding the firm, Mr. Reiter was vice president and 
general counsel for 724 Solutions Inc., a provider of mobile commerce software solutions and applications (NASDAQ: SVNX). 
Earlier in his career, Mr. Reiter served as senior counsel for Compaq Computer Corporation, supporting the Worldwide Sales & 
Services,  Supply  Chain  Management  and  Consumer  Products  Group.  Mr. Reiter  is  a  graduate  of  the  University  of  Southern 
California (Juris Doctorate/Master of International Relations), University of Sheffield, UK (M.B.A.) and the University of Notre 
Dame (B.A.) in Government. Mr. Reiter is a member of the Texas Bar and the American Bar Association.  

18

                                   
   
ITEM 1A. RISK FACTORS  

We expect our operating results to continue to fluctuate from quarter to quarter.  

The sale of our instrumentation and assay products typically involves a significant technical evaluation and commitment of 
capital by us, our partners and the end user. Accordingly, the sales cycle associated with our products typically is lengthy and 
subject  to  a  number  of  significant  risks,  much  of  which  is  beyond  our  control,  including  partners’  budgetary  constraints, 
inventory  management  practices,  regulatory  approval  and  internal  acceptance  reviews.  As  a  result  of  this  lengthy  and 
unpredictable sales cycle, our operating results have historically fluctuated significantly from quarter to quarter. We expect this 
trend to continue for the foreseeable future.  

The  vast  majority  of  our  system  sales  are  made  to  our  strategic  partners.  Our  partners  typically  purchase  instruments  in 
three  phases  during  their  commercialization  cycle:  first, instruments  necessary  to  support  internal  assay  development;  second, 
instruments for sales force demonstrations; and finally, instruments for resale to their customers. As a result, most of our system 
placements are highly dependent on the continued commercial success of our strategic partners and can fluctuate from quarter to 
quarter as our strategic partners move from phase to phase. We expect this trend to continue for the foreseeable future.  

Our assay products are sometimes sold to large customers. The ordering and consumption patterns of these customers can 
fluctuate,  affecting  the  timing  of  shipments  and  revenue  recognition.  In  addition,  certain  products  assist  in  the  diagnosis  of 
illnesses that are seasonal, and customer orders can fluctuate for this reason.  

Because of the effect of bulk purchases, defined as the purchase of $100,000 or more of consumables in a quarter, and the 
introduction of seasonal components to our assay menus, we experience fluctuations in the percentage of our quarterly revenues 
derived  from  our  highest  margin  items:  consumables,  royalties  and  assays.  Our  gross  margin  percentage  is  highly  dependent 
upon the mix of revenue components each quarter. These fluctuations contribute to the variability and lack of predictability of 
both gross margin percentage and total gross profit from quarter to quarter. We expect this trend to continue for the foreseeable 
future.  

Due to the early stage of the market for molecular tests, projected growth scenarios for the assay segment are highly volatile 
and  are  based  on  a  number  of  underlying  assumptions  that  may  or  may  not  prove  to  be  valid,  including  the  performance  of 
strategic partners that distribute our assay segment products.  

We have a limited history of profitability and had an accumulated deficit of approximately $67.0 million as of December 31, 
2009.  

We  have  incurred  significant  net  losses  since  our  inception.  At  December 31,  2009,  we  had  an  accumulated  deficit  of 
approximately  $67.0 million.  In  order  to  remain  profitable,  we  need  to  sustain  or  increase  our  revenues  while  achieving 
reasonable  cost  and  expense  levels.  We  believe  that  we  have  achieved  a  level  of  consistent  profitability  from  our  continuing 
operations; however, we cannot be certain that we can sustain or increase profitability on a quarterly or annual basis. If we fail to 
achieve  operating  results  in  line  with  market  expectations,  the  market  price  of  our  common  stock  will  likely  decline. 
Furthermore,  as we  continue  to  utilize  cash to support  operations,  acquisitions and  research  and development efforts,  we may 
further  decrease  the  cash  available  to  us.  As  of  December 31,  2009,  cash,  cash  equivalents  and  short-term  and  long-term 
investments totaled $119.6 million, compared to $124.1 million at December 31, 2008. The decrease since December 31, 2008 is 
primarily attributable to capital expenditures and an increase in our accounts receivable as of December 31, 2009.  

19

                                   
   
Our  success  depends  significantly  on  the  establishment  and  maintenance  of  successful  relationships  with  our  strategic 
partners. Currently, a limited number of strategic partners account for a majority of our revenue and the loss of any one of 
these  partners  or  their  inability  to  perform  to  expectations  could  have  a  material  adverse  effect  on  our  business,  financial 
condition and results of operations.  

The development and commercialization of our xMAP technology is highly dependent on our ability to establish successful 
strategic relationships with a number of partners. For the twelve months ended December 31, 2009, we had 39 strategic partners 
submitting royalties as compared to 35 for the twelve months ended December 31, 2008. Two customers, One Lambda, Inc. and 
Bio-Rad  Laboratories,  Inc.,  accounted  for  26%  of  consolidated  total  revenue  in  the  twelve  months  ended  December 31,  2009 
(15% and  11%, respectively). For  comparative purposes, these  same  two  customers accounted  for  36%  of  total revenue  (19% 
and 17%, respectively) in the twelve months ended December 31, 2008. No other customer accounted for more than 10% of total 
revenue  during  the  twelve  months  ended  December 31,  2009.  We  had  only  three  additional  partners  who  individually 
represented 5% or more of our total revenue and collectively represented 22% of our revenue for the year ended December 31, 
2009. In total, for the year ended December 31, 2009, our top five partners accounted for 48% of our total revenue. In total, for 
the  year  ended  December 31,  2008,  our  top  five  partners  accounted  for  53%  of  our  total  revenue.  The  loss  of  any  of  our 
significant strategic partners, or any of our significant customers, could have a material adverse effect on our growth and future 
results of operations. The assay segment is dependent on a few significant customers with respect to sales of its genetic test kits. 
If any significant customer discontinues its relationship with the assay segment for any reason, or reduces or postpones current or 
expected  purchase  commitments  for  the  assay  segment’s  products,  the  assay  segment’s  results  from  operations  could  be 
materially adversely affected.  

Delays  in  implementation,  delays  in  obtaining  regulatory  approval,  changes  in  strategy  or  the  financial  difficulty  of  our 
strategic  partners  for  any  reason  could  have  a  material  adverse  effect  on  our  business,  financial  condition  and  results  of 
operations.  

Our  ability  to  enter  into  agreements  with  additional  strategic  partners  depends  in  part  on  convincing  them  that  our 
technology can help achieve and accelerate their goals or efforts. We will expend substantial funds and management efforts with 
no  assurance  that  any  additional  strategic  relationships  will  result.  We  cannot  assure  you  that  we  will  be  able  to  negotiate 
additional  strategic  agreements  in  the  future  on  acceptable  terms,  if  at  all,  or  that  current  or  future  strategic  partners  will  not 
pursue or  develop alternative  technologies  either  on  their  own  or  in  collaboration  with  others. Some  of the  companies  we are 
targeting  as  strategic  partners  offer  products  competitive  with  our  xMAP  technology,  which  may  hinder  or  prevent  strategic 
relationships.  Termination  of  strategic  relationships,  the  failure  to  enter  into  a  sufficient  number  of  additional  strategic 
relationships on favorable terms, or disputes with our partners could reduce sales of our products, lower margins on our products 
and limit the creation of market demand for and acceptance of our products.  

In  most  of  our  strategic  relationships  we  have  granted  our  strategic  partners  non-exclusive  rights  with  respect  to 
commercialization  of  our  products  and  technology.  The  lack  of  exclusivity  could  deter  existing  strategic  partners  from 
commercializing xMAP technology and may deter new strategic partners from entering into agreements with us.  

A significant portion of our future revenues will come from sales of our systems and the development and sale of bioassay 
kits  utilizing  our  technology  by our  strategic  partners  and  from  use  of  our  technology  by  our  strategic  partners  in  performing 
services offered to third parties. We believe that our strategic partners will have economic incentives to develop and market these 
products,  but  we  cannot  accurately  predict  future  sales  and  royalty  revenues  because  most  of  our  existing  strategic  partner 
agreements do not include minimum purchase requirements or minimum royalty commitments. In addition, we have no control 
with respect to our strategic partners’ sales personnel and how they prioritize products based on xMAP technology nor can we 
control the timing of the development or release of products by our strategic partners. The amount of these revenues depends on 
a variety of factors  that are outside our control, including the amount and  timing  of resources that current and future strategic 
partners devote to develop and market products incorporating our technology. Further, the development and marketing of certain 
bioassay  kits  will  require  our  strategic  partners  to  obtain  governmental  approvals,  which  could  delay  or  prevent  their 
commercialization efforts. If our current or future strategic partners do not successfully develop and market products based on 
our technology and obtain necessary government approvals, our revenues from product sales and royalties will be significantly 
reduced.  

20

                                   
   
Current economic conditions and the uncertain economic outlook may adversely impact our business, results of operations, 
financial condition or liquidity.  

Global economic conditions may remain challenging and uncertain for the foreseeable future. The  credit markets and the 
financial  services  industry  have  been  experiencing  a  period  of  unprecedented  turmoil  and  upheaval  characterized  by  the 
bankruptcy, failure, collapse or sale of various financial institutions and an unprecedented level of intervention from the United 
States  federal  government.  These  conditions  not  only  limit  our  access  to  capital  but  also  make  it  extremely  difficult  for  our 
customers, our vendors and us to accurately forecast and plan future business activities, and they could cause U.S. and foreign 
businesses and consumers to slow spending on our products and services, which would delay and lengthen sales cycles. Some of 
our  customers  rely on  government  research  grants  to  fund  technology  purchases. If  negative  trends  in  the  economy affect  the 
government’s allocation of funds to research, there may be less grant funding available for certain of our customers to purchase 
technologies like those Luminex sells. Certain of our partners and their and our customers may face challenges gaining timely 
access to sufficient credit or may otherwise be faced with budget constraints, which could result in decreased purchases of, or 
development  of  products  based  on,  our  products  or  in  an  impairment  of  their  ability  to  make  timely  payments  to  us.  If  our 
partners and our customers do not make timely payments to us, we may be required to assume greater credit risk relating to those 
customers, increase our allowance for doubtful accounts and our days sales outstanding would be negatively impacted. Although 
we maintain allowances for doubtful accounts for estimated losses resulting from the inability of our customers to make required 
payments and such losses have historically been within our expectations and the provisions established, we may not continue to 
experience  the  same  loss  rates  that  we  have  in  the  past,  especially  given  the  current  turmoil  of  the  worldwide  economy. 
Additionally,  these  economic  conditions  and  market  turbulence  may  also  impact  our  suppliers  causing  them  to  be  unable  to 
supply  in  a  timely  manner  sufficient  quantities  of  customized  components,  thereby  impairing  our  ability  to  manufacture  on 
schedule and at commercially reasonable costs.  

If the FDA or other governmental laws and regulations change in ways that we do not anticipate and we fail to comply with 
those  regulations  that  affect  our  business,  we  could  be  subject  to  enforcement  actions,  injunctions  and  civil  and  criminal 
penalties or otherwise be subject to increased costs that could delay or prevent marketing of our products.  

The production, testing, labeling, marketing and distribution of our products for some purposes and products based on our 
technology are subject to governmental regulation by the FDA and by similar agencies in other countries. Some of our products 
and products based on our technology for in vitro diagnostic purposes are subject to clearance by the FDA prior to marketing for 
commercial use. To date, eight strategic partners have obtained such clearances. Others are anticipated. The process of obtaining 
necessary FDA clearances can be time-consuming, expensive and uncertain. Further, clearance may place substantial restrictions 
on  the  indications for  which  the product  may  be  marketed  or  to  whom  it  may  be  marketed.  In  addition, because  some  of  our 
products  employ  laser  technology,  we  are  also  required  to  comply  with  FDA  requirements  relating  to  radiation  performance 
safety standards.  

Periodically  the  FDA  issues  guidance  documents  that  represent  the  FDA’s  current  thinking  on  a  topic.  These  issues  are 
initially  issued  in  draft  form  prior to  final  rule generally  with  enforcement  discretion  for  some grace period  of  time.  Changes 
made through this process may impact the release status of products offered and our ability to market those products affected by 
the change. For example, the FDA released on September 14, 2007 the final document “Guidance for Industry and FDA Staff 
Commercially Distributed Analyte Specific Reagents (ASRs): Frequently Asked Questions.” This guidance may limit or delay 
distribution of assays on our platform, including assays developed and distributed by our assay segment, to the extent additional 
regulatory clearance is required prior to distribution.  

Cleared  medical  device  products  are  subject  to  continuing  FDA  requirements  relating  to,  among  others,  manufacturing 
quality control and quality assurance, maintenance of records and documentation, registration and listing, import/export, adverse 
event and other reporting, distribution, labeling and promotion and advertising of medical devices. Our inability or the inability 
of  our  strategic  partners  to  obtain  required  regulatory  approval  or  clearance  on  a  timely  or  acceptable  basis  could  harm  our 
business.  In  addition,  failure  to  comply  with  applicable  regulatory  requirements  could  subject  us  or  our  strategic  partners  to 
regulatory enforcement  action,  including  warning  letters, product seizures, recalls,  withdrawal  of clearances,  restrictions on or 
injunctions against marketing our products or products based on our technology, and civil and criminal penalties.  

21

                                   
   
Medical device laws and regulations are in  effect within the United  States and also in many countries outside the United 
States.  These  range  from  comprehensive  device  clearance  requirements  for  some  or  all  of  our  medical  device  products  to 
requests  for  product  data  or  certifications  regarding  the  hazardous  material  content  of  our  products.  As  part  of  the  European 
Council  Directive 2002/96 of February 13,  2003  (WEEE), we are expected  to  comply with certain requirements regarding the 
collection, recycling and labeling of our products containing electronic devices in each of the European Union, or EU, member 
states where  our  regulated products are distributed. While we are  taking steps to  comply with  the requirements  of WEEE, we 
cannot be certain that we will comply with the national stage implementation of WEEE in all member states. Our products are 
currently exempt from the European Council Directive 2002/95 of January 27, 2003, Restriction of the Use of Certain Hazardous 
Substances  in  Electrical  and  Electronic  Equipment  (RoHS),  which  required  the  removal  of  certain  specified  hazardous 
substances  from  certain  products  beginning  July 1,  2006  in  each  of  the  member  states.  However,  the  EU  has  indicated  that  it 
may,  and  it  is  generally  expected  it  will,  include  medical  devices,  including  some  of  our  products,  under  the  jurisdiction  of 
RoHS. If this exemption is revoked, it could result in increased costs to us and we cannot assure you we will ultimately be able to 
comply  with  RoHS  or  related  requirements  in  other  jurisdictions.  In  addition,  the  State  of  California  adopted  the  Electronic 
Waste Recycling Act, effective January 1, 2007, which requires the California Department of Toxic Substances Control to adopt 
regulations to prohibit the sale of electronic devices in California if they are also prohibited from sale in the EU under the RoHS 
directive  because  they  contain  certain  heavy  metals.  The  number  and  scope  of  these  requirements  are  increasing  and  we  will 
likely become subject to further similar laws in other jurisdictions. Failure to comply with applicable federal, state and foreign 
medical device laws and regulations may harm our business, financial condition and results of operations. We are also subject to 
a  variety  of  other  laws  and  regulations  relating  to,  among  other  things,  environmental  protection  and  workplace  health  and 
safety.  

Our  strategic  partners  and  customers  expect  our  organization  to  operate  on  an  established  quality  management  system 
compliant  with  FDA  Quality  System  Regulations  and  industry  standards,  the  In  Vitro  Diagnostic  Directive  98/79/EC  of  27 
October 1998  (Directive)  as  implemented  nationally  in  the  EU  member  states  and  industry  standards,  such  as  ISO  9000.  We 
became ISO 9001:2000 certified in March 2002 and self-declared our Luminex 100 and Luminex 200 devices are in conformity 
with Article 1, Article 9, Annex I (Essential Requirements), and Annex III, and the additional provisions of the Directive as of 
December 7, 2003. Subsequent audits are carried out annually to ensure we maintain our system in substantial compliance with 
ISO  and  other  applicable  regulations  and  industry  standards.  We  became  ISO  13485:2003  and  Canadian  Medical  Device 
Conformity  Assessment  System  (CMDCAS) certified  in  July 2005.  In  August 2006  a  Level  II  QSIT  contract  inspection  was 
conducted  in  accordance  with  CPGM  7382.845,  Inspection  of  Medical  Device  Manufacturers,  PAC  82845B,  Medical  Device 
Level II Inspections pursuant to the FDA Dallas District Office FY 06 Workplan and the DSHS Drugs & Medical Device Group 
FY  06  Workplan.  The  inspection  is  “closed”  under  21  C.F.R.  20.64  (d)  (3) and  the  Establishment  Inspection  Report 
No. 3002524000  provided  in  accordance  with  the  FOIA  and  21  C.F.R.  Part 20.  No  DSHS  form  E-14  or  FDA  form  483  was 
issued.  Failure  to  maintain  compliance  with  FDA,  CMDCAS  and  EU  regulations  and  other  medical  device laws,  or  to  obtain 
applicable registrations where required, could reduce our competitive advantage in the markets in which we compete and also 
decrease satisfaction and confidence levels with our partners.  

22

                                   
   
If our technology and products do not become widely used in the life sciences and clinical diagnostics industries, it is unlikely 
that we can maintain or increase profitability.  

Life sciences companies have historically conducted biological tests using a variety of technologies, including bead-based 
analysis. In  certain testing  areas, our  xMAP technology  is  relatively new and  unproven,  and the use of our technology  by  life 
sciences companies is limited. The commercial success of our technology depends upon its widespread adoption as a method to 
perform  bioassays.  In  order  to  be  successful,  we  must  convince  potential  partners  to  utilize  our  system  instead  of  competing 
technologies. Market acceptance depends on many factors, including our ability to:  

•

•

•

•

•

  convince prospective strategic partners and customers that our technology is an attractive alternative to other technologies

for pharmaceutical, research, clinical, biomedical and genetic testing and analysis; 

  encourage these partners to develop and market products using our technology; 

  manufacture products in sufficient quantities with acceptable quality and at an acceptable cost; 

  obtain and maintain sufficient pricing and royalties from partners on such Luminex products; and 

  place and service sufficient quantities of our products, including the ability to provide the level of service required in the

mainstream clinical diagnostics market segment. 

Because  of  these  and  other  factors,  our  products  may  not  gain  or  sustain  sufficient  market  acceptance  to  again  achieve, 

maintain or increase profitability.  

Our reliance on strategic relationships to market many of our products makes forecasting difficult.  

As a result of our reliance on our strategic relationships, it can be difficult to accurately forecast future operating results. 
Our  operating  expenses  are  largely  based  on  anticipated  revenue  trends,  and  a  high  percentage  of  our  expenses  are,  and  will 
continue  to  be,  fixed  in  the  short-term.  The  level  of  our  revenues  depends  upon  the  rate  and  timing  of  the  adoption  of  our 
technology as a method  to  perform bioassays. In addition,  we  currently  anticipate that the vast majority  of  future  sales of  our 
products  and  products  incorporating  our  technology  will  be  made  by  through  our  strategic  relationships.  For  the  following 
reasons,  estimating  the  timing  and  amount  of  sales  of  these  products  that  may  be  made  through  our  strategic  relationships  is 
particularly difficult:  

•

•

•

•

•

•

•

•

  We have no control over the timing or extent of product development, marketing or sale of our products by our strategic

partners. 

  We do not control the incentives provided by our strategic partners and distributors to their sales personnel. 

  We  utilize  distributors  for  a  portion  of  our  sales,  including  several  of  our  key  assay  products  and  the  loss  of  or  non-

performance by these distributors could harm our revenues in the territories serviced by these distributors. 

  A  significant  number  of  our  strategic  partners  intend  to  produce  clinical  diagnostic  applications  that  may  need  to  be

approved by the FDA, or other regulatory bodies in jurisdictions outside of the United States. 

  Certain strategic partners may have unique requirements for their applications and systems. Assisting the various strategic
partners may strain our research and development and manufacturing resources. To the extent that we are not able to timely
assist our strategic partners, the commercialization of their products will likely be delayed.

  Certain strategic partners may fail to deliver products that satisfy market requirements, or such products may fail to perform

properly. 

  We  have  limited  access  to  partner  and  distributor  confidential  corporate  information.  A  sudden  unexpected  change  in

ownership, strategy or other material event could adversely impact partner purchases of our products. 

  Partners tend to order in bulk prior to the production of new lots of their products and prior to major product development
initiatives.  The  frequency  of  these  bulk  purchases  is  difficult  to  predict  and  may  cause  large  fluctuations  in  microsphere
sales quarter to quarter. 

23

                                   
   
 
 
 
 
 
 
 
 
 
 
 
The life sciences industry is highly competitive and subject to rapid technological change, and we may not have the resources 
necessary to compete successfully.  

We compete with companies in the United States and abroad that are engaged in the development and production of similar 
products. We will continue to face intense competition from existing competitors and other companies seeking to develop new 
technologies.  Many  of  our  competitors  have  access  to  greater  financial,  technical,  scientific,  research,  marketing,  sales, 
distribution, service and other resources than we do. These companies may develop technologies that are superior alternatives to 
our technologies or may be more effective at commercializing their technologies in products.  

The life sciences industry is characterized by rapid and continuous technological innovation. We may need to develop new 
technologies for our products to remain competitive. One or more of our current or future competitors could render our present 
or future products or those of our partners obsolete or uneconomical by technological advances. In addition, the introduction or 
announcement of new products by us or others could result in a delay of or decrease in sales of existing products, as we await 
regulatory approvals, while customers evaluate these new products, or if customers choose to purchase the new products instead 
of legacy products. We may also encounter other problems in the process of delivering new products to the marketplace such as 
problems  related  to  design,  development,  supply  chain  or  manufacturing  of  such  products,  and  as  a  result  we  may  be 
unsuccessful  in  selling  such  products.  Our  future  success  depends  on  our  ability  to  compete  effectively  against  current 
technologies,  as  well  as  to  respond  effectively  to  technological  advances  by  developing  and  marketing  products  that  are 
competitive in the continually changing technological landscape.  

Our  success  depends  on  our  ability  to  service  and  support  our  products  directly  or  in  collaboration  with  our  strategic 
partners.  

To  the  extent  that  we  or  our  strategic  partners  fail  to  maintain  a  high  quality  level  of  service  and  support  for  xMAP 
technology  products,  there  is  a  risk  that  the  perceived  quality  of  our  xMAP  technology  products  will  be  diminished  in  the 
marketplace. Likewise, we may fail to provide the level, quantity or quality of service expected by the marketplace. This could 
result  in  slower  adoption  rates  and  lower  than  anticipated  utilization  of  xMAP  products  which  could  have  a  material  adverse 
affect on our business, financial condition and results of operations.  

The property rights we rely upon to protect the technology underlying our products may not be adequate to maintain market 
exclusivity. Inadequate intellectual property protection could enable third parties to exploit our technology or use very similar 
technology and could reduce our ability to distinguish our products in the market.  

Our success depends, in part, on our ability to obtain, protect and enforce patents on  our technology and products and to 
protect our trade secrets, including the intellectual property of entities we may acquire. Any patents we own may not afford full 
protection for our technology and products. Others may challenge our patents and, as a result, our patents could be narrowed or 
invalidated. In addition, our current and future patent applications may not result in the issuance of patents in the United States or 
foreign countries. Competitors may develop products that are not covered by our patents. Further, there is a substantial backlog 
of patent applications at the U.S. Patent and Trademark Office and certain patent offices in foreign jurisdictions, and the approval 
or rejection of patent applications may take several years.  

We have obtained 89 patents in the United States and foreign jurisdictions directed to various aspects and applications of 
our products and technology. We have 215 pending applications in the United States and foreign jurisdictions. In Japan, due to a 
procedural  omission,  we  are  unable  to  obtain  patent  protection  for  our  method  of  “real  time”  detection  and  quantification  of 
multiple  analytes  from  a  single  sample  on  our  platform  technology  similar  to  the  protection  we  have  obtained  in  the  United 
States. Although we are pursuing patent protection in Japan for other aspects of our technology and products, we may not be able 
to prevent competitors from developing and marketing technologies and products similar to our xMAP technology in Japan. We 
also have patents covering key aspects of xTAG technology utilized in our assay products.  

24

                                   
   
We require our employees, consultants, strategic partners and other third parties to execute confidentiality agreements. Our 
employees  and  third-party  consultants  also  sign  agreements  requiring  that  they  assign  to  us  their  interests  in  inventions  and 
original  expressions  and  any  corresponding  patents  and  copyrights  arising  from  their  work  for  us.  In  addition,  we  have 
implemented  a  patent  process  to  file  patent  applications  on  our  key  technology.  However,  we  cannot  guarantee  that  these 
agreements or this patent process will provide us with adequate protection against improper use of our intellectual property or 
disclosure of confidential information. In addition, in some situations, these agreements may conflict with, or be subject to, the 
rights  of  third  parties  with  whom  our  employees,  consultants  or  advisors  have  prior  employment  or  consulting  relationships. 
Further,  others  may  independently  develop  substantially  equivalent  proprietary  technology,  techniques  and  products  or 
counterfeit  versions  of  our  products  or  otherwise  gain  access  to  our  trade  secrets.  Our  failure  to  protect  our  proprietary 
information and techniques may inhibit or limit our ability to exclude certain competitors from the market.  

In  order  to  protect  or  enforce  our  patent  rights,  we  may  have  to  initiate  legal  proceedings  against  third  parties,  such  as 
infringement suits or interference proceedings. These legal proceedings could be expensive, take significant time and/or divert 
management’s  attention  from  other  business  concerns.  These  proceedings  may  cause  us  to  lose  the  benefit  of  some  of  our 
intellectual property rights, the loss of which may inhibit or preclude our ability to exclude certain competitors from the market. 
These proceedings also may provoke these third parties to assert claims against us. The patent position of companies like ours 
generally is highly uncertain, involves complex legal and factual questions and has recently been the subject of much litigation. 
No  consistent  policy  has  emerged  from  the  U.S.  Patent  and  Trademark  Office  or  the  courts  regarding  the  breadth  of  claims 
allowed or the degree of protection afforded under patents like ours.  

Our  success  depends  partly  on  our  ability  to  operate  without  infringing  on  or  misappropriating  the  proprietary  rights  of 
others.  

We  have  been  (and  from  time  to  time  we  may  be)  notified  that  third  parties  consider  their  patents  or  other  intellectual 
property relevant to our products. We may be sued for infringing the intellectual property rights of others, including claims with 
respect  to  intellectual  property  of  entities  we  may  acquire.  In  addition,  we  may  find  it  necessary,  if  threatened,  to  initiate  a 
lawsuit seeking a declaration from a court that we do not infringe on the proprietary rights of others or that their rights are invalid 
or  unenforceable.  Intellectual  property  litigation  is  costly,  and,  even  if  we  prevail,  the  cost  of  such  litigation  could  affect  our 
profitability. Furthermore, litigation is time  consuming and  could  divert management’s attention and  resources away  from our 
business. If we do not prevail in any litigation, we may have to pay damages and could be required to stop the infringing activity 
or obtain a license. Any required license may not be available to us on acceptable terms, if at all. Moreover, some licenses may 
be nonexclusive, and  therefore,  our  competitors  may have access  to  the same technology  licensed  to us. If we fail to obtain  a 
required  license or  are  unable  to  design around  a  patent, we  may  be  unable  to  sell some  of  our products,  which could have  a 
material adverse affect on our business, financial condition and results of operations.  

We require collaboration with other organizations in obtaining relevant biomarkers, access to oligonucleotides and enzymes 
that  are  patented  or  controlled  by others.  If  we  cannot continue  to  obtain  access to  these  areas  or  identify  freedom  to operate 
opportunities, our business, financial condition and results of operations could be negatively affected.  

25

                                   
   
We  have only  produced  our  products in limited  quantities,  and we  may experience  problems  in  scaling our  manufacturing 
operations or delays or component shortages that could limit the growth of our revenue.  

To date, we have produced our products in limited quantities relative to the quantities necessary to achieve desired revenue 
growth. We may not be able to produce sufficient quantities or maintain consistency between differing lots of consumables. If 
we encounter difficulties in scaling our manufacturing operations as a result of, among other things, quality control and quality 
assurance  issues  and  availability  of  components  and  raw  material  supplies,  we  will  likely  experience  reduced  sales  of  our 
products, increased repair or re-engineering costs due to product returns, and defects and increased expenses due to switching to 
alternate suppliers, any of which would reduce our revenues and gross margins.  

We presently outsource certain aspects of the assembly of our systems to contract manufacturers. Because of a long lead-
time to delivery, we are required to place orders for a variety of items well in advance of scheduled production runs. We recently 
increased our flexibility to purchase strategic components within shorter lead times by entering into supply agreements with the 
suppliers  of  these  components.  Although  we  attempt  to  match  our  parts  inventory  and  production  capabilities  to  estimates  of 
marketplace demand, to the extent system orders materially vary from our estimates, we may experience continued constraints in 
our systems production and delivery capacity, which could adversely impact revenue in a given fiscal period. Should our need 
for raw materials and components used in production continue to fluctuate, we could incur additional costs associated with either 
expediting or postponing delivery of those materials. In an effort to control costs, during the last quarter of 2005 we implemented 
a  lean  production  system.  Managing  the  change  from  discrete  to  continuous  flow  production  requires  time  and  management 
commitment. Lean initiatives and limitations in our supply chain capabilities may result in part shortages that delay shipments 
and cause fluctuations in revenue in a given period.  

We currently purchase certain key components of our product line from a limited number of outside sources and may only 
be available  through  a limited  number of providers. We do not have  agreements  with all of our  suppliers. While we  currently 
believe that we will be able to satisfy our forecasted demand for our kits, the failure to find alternative suppliers in the event of a 
supply  failure  at  any  of  our  current  vendors  at  reasonably  comparable  prices  could  have  a  material  adverse  effect  on  our 
business, financial condition and results of operations. Additionally, we have entered into supply agreements with most of our 
suppliers  of  strategic  reagents  and  component  subassemblies  to  help  ensure  component  availability,  and  flexible  purchasing 
terms with respect to the purchase of such components. Our reliance on our suppliers and contract manufacturers exposes us to 
risks including:  

•

•

•

•

•

•

  the  possibility  that  one  or  more  of  our  suppliers  or  our  assemblers  that  do  not  have  supply  agreements  with  us  could

terminate their services at any time without penalty;

  the potential obsolescence and/or inability of our suppliers to obtain required components;

  the potential delays and expenses of seeking alternate sources of supply or manufacturing services; 

  the inability to qualify alternate sources without impacting performance claims of our products; 

  reduced  control  over  pricing,  quality  and  timely  delivery  due  to  the  difficulties  in  switching  to  alternate  suppliers  or

assemblers; and 

  increases in prices of raw materials and key components.

Consequently,  in  the  event  that  supplies  of  components  or  work  performed  by  any  of  our  assemblers  are  delayed  or 

interrupted for any reason, our ability to produce and supply our products could be impaired.  

26

                                   
   
 
 
 
 
 
International business operations create additional operational and legal risk.  

Our  future  profitability  will  depend  in  part  on  our  ability  to  grow  and  ultimately  maintain  our  product  sales  in  foreign 
markets,  particularly  in  Asia  and  Europe.  Our  plans  to  expand  globally  will  expose  us  to  additional  foreign  currency  risk  in 
multiple currencies. Our operations outside the United States are subject to additional risks, including:  

•

•

•

•

•

•

•

•

•

•

•

•

•

•

•

•

•

•

  changes in or interpretations of foreign law that may adversely affect our ability to sell our products, perform services or

repatriate profits to the United States; 

  the imposition of tariffs; 

  hyperinflation or economic or political instability in foreign countries;

  imposition  of  limitations  on  or  increase  of  withholding  and  other  taxes  on  remittances  and  other  payments  by  foreign

subsidiaries; 

  conducting business in places where business practices and customs are unfamiliar and unknown; 

  the burden of complying with complex and changing foreign regulatory requirements; 

  longer accounts receivable collection times; 

  the imposition of restrictive trade policies, including export restrictions;

  worldwide political conditions; 

  the imposition of inconsistent laws or regulations; 

  reduced protection of intellectual property rights in some foreign countries;

  the imposition or increase of investment requirements and other restrictions by foreign governments; 

  longer collection cycles for account receivables; 

  the interpretation of contractual provisions governed by foreign laws in the event of a contract dispute; 

  uncertainties relating to foreign laws, including labor laws, and legal proceedings;

  significant currency fluctuations;

  having to comply with a variety of U.S. laws, including the Foreign Corrupt Practices Act; and 

  having to comply with U.S. export control regulations and policies that restrict our ability to communicate with non-U.S. 

employees and supply foreign affiliates, partners and customers.

The capital spending policies of our customers have a significant effect on the demand for our products.  

Our  customers  include  clinical  diagnostic,  pharmaceutical,  biotechnological,  chemical  and  industrial  companies,  and  the 
capital spending  policies  of  these  companies  can  have  a  significant effect  on the  demand  for our  products. These  policies  are 
based  on a wide variety of factors, including  governmental regulation or price controls, the resources available for purchasing 
research  equipment,  the  spending  priorities  among  various  types  of  analytical  equipment  and  the  policies  regarding  capital 
expenditures during recessionary periods. Any decrease in capital spending by life sciences companies could cause our revenues 
to  decline.  As  a  result,  we  are  subject  to  significant  volatility  in  revenue.  Therefore,  our  operating  results  can  be  materially 
affected (negatively and positively) by the spending policies and priorities of our customers.  

27

                                   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
If we become subject to product liability claims, we may be required to pay damages that exceed our insurance coverage.  

Our business exposes us to potential product liability claims that are inherent in the testing, production, marketing and sale 
of biotechnological, human (including genetic) diagnostic and therapeutic products. Although we believe that we are reasonably 
insured  against  these  risks  and  we  generally  have  limited  indemnity  protections  in  our  supplier  agreements,  there  can  be  no 
assurance that we will be able to obtain insurance in amounts or scope sufficient to provide us with adequate coverage against all 
potential  liabilities.  A  product  liability  claim  in  excess  of  our  insurance  coverage  or  claim  that  is  outside  or  exceeds  our 
indemnity  protections  in  our  supplier  agreements  or  a  recall  of  one  of  our  products  would  have  to  be  paid  out  of  our  cash 
reserves.  

If third-party payors increasingly restrict payments for healthcare expenses or fail to adequately pay for multi-analyte testing, 
we may experience reduced sales which would hurt our business and our business prospects.  

Third-party  payors,  such  as  government  entities  and  healthcare  programs,  health  maintenance  organizations  and  private 
insurers, are continually seeking to reduce healthcare expenses. The federal government has also recently reduced the funding for 
certain  government  sponsored  healthcare  programs  which  has  caused  these  third  party  payors  to  seek  further  reduction  in 
medical  expenses.  The  federal  government  is  also  considering  comprehensive  healthcare  reform,  which  could  further  limit 
government  reimbursement  to  these  payors.  These  reductions  may  decrease  demand  for  our  products  and  the  price  we  can 
charge.  Increasingly,  Medicaid  and other  third-party  payors are  challenging  the prices  charged  for medical  services,  including 
clinical diagnostic tests. They are also attempting to contain costs by limiting coverage and the reimbursement level of tests and 
other  healthcare  products.  In  addition,  cost  containment  initiatives  by  governmental  or  educational  entities  or  programs  may 
reduce funding for genetic research and development activities and retard the growth of the genetic testing marketing. Without 
adequate  coverage  and  reimbursement,  consumer  demand  for  tests  will  decrease.  Decreased  demand  could  cause  sales  of  our 
products, and sales and services by our strategic partners, to fall. In addition, decreased demand could place pressure on us, or 
our strategic partners, to lower prices on these products or services, resulting in lower margins. Reduced sales or margins by us, 
or our strategic partners, would hurt our business, profitability and business prospects.  

We may in the future incur substantial debt that could restrict our operations.  

We  may  incur  indebtedness  in  the  future  for,  among  other  purposes,  funding  operating  expenses  and/or  costs  related  to 

future expansions and acquisitions. This indebtedness could have adverse consequences on us, including:  

•

•

•

  limiting our ability to compete and our flexibility in planning for, or reacting to, changes in our business and the industry in

which we operate; 

  limiting  our  ability  to  borrow  additional  funds  for  working  capital,  capital  and  research  and  development  expenditures,

acquisitions and general corporate or other purposes; and

  exposing us to interest rate risk.

To the extent incurred, our debt service obligations will require us to use a portion of our operating cash flow to pay interest 
and principal  on  indebtedness instead  of  for  other  corporate purposes, including funding future expansion of our business and 
ongoing  capital  expenditures.  Our  ability  to  repay  or  refinance  our  debt  depends  on  our  successful  financial  and  operating 
performance. Our financial and operating performance depends upon a number of factors, many of which are beyond our control, 
as further described in this Item 1A “Risk Factors.”  

28

                                   
   
 
 
We may be unsuccessful in implementing our acquisition strategy. We may face difficulties integrating acquired entities with 
our existing businesses.  

Acquisitions of assets or entities designed to accelerate the implementation of our strategic plan are an element of our long-
term strategy. We may be unable to identify and complete appropriate future acquisitions in a timely manner and no assurance 
can be provided that the market price of potential business acquisitions will be acceptable. In addition, many of our competitors 
have  greater  financial  resources  than  we  have  and  may  be  willing  to  pay  more  for  these  businesses  or  selected  assets.  In  the 
future,  should  we  identify  suitable  acquisition  targets,  we  may  be  unable  to  complete  acquisitions  or  obtain  the  financing,  if 
necessary,  for  these  acquisitions  on  terms favorable to us. Generally,  potential acquisitions  pose  a number  of risks, including, 
among others, that:  

•

•

•

•

•

•

•

•

•

•

•

  we may not be able to accurately estimate the financial effect of acquisitions on our business; 

  future acquisitions may require us to assume liabilities, incur large and immediate write-offs, issue capital stock potentially 
dilutive to our stockholders or spend significant cash or may result in a decrease in our future operating income or operating
margins; 

  we  may  be  unable  to  realize  the  anticipated  benefits  and  synergies  from  acquisitions  as  a  result  of  inherent  risks  and
uncertainties, including difficulties integrating acquired businesses or retaining their key personnel, partners, customers or
other  key  relationships,  entering  market  segments  in  which  we  have  no  or  limited  experience,  and  risks  that  acquired
entities may not operate profitably or that acquisitions may not result in improved operating performance; 

  acquisitions  and  subsequent  integration  of  these  companies  may  disrupt  our  business  and  distract  our  management  from

other responsibilities; and 

  the costs of unsuccessful acquisition efforts may adversely affect our financial performance.

  Other risks of integration include:

  disparate information technology, internal control, financial reporting and record-keeping systems; 

  differences in accounting policies, including those requiring judgment or complex estimation processes; 

  new partners or customers who may operate on terms and programs different than ours;

  additional employees not familiar with our operations;

  facilities  or  operations  in  remote  locations  or  potentially  foreign  jurisdictions  and  the  inherent  risks  of  operating  in

unfamiliar legal and regulatory environments; and 

  new products, including the risk that any underlying intellectual property associated with such products may not have been

adequately protected or that such products may infringe on the proprietary rights of others.

We rely on the innovation and resources  of larger industry participants and public  programs to advance genomic research 
and educate physicians/clinicians on genetic diagnostics.  

The  linkages  between  genetic  anomalies  that  our  products  detect  and  the  underlying  disease  states  are  not  always  fully 
medically  correlated.  Additionally,  the  availability  of  correlated  genetic  markers  is  dependent  on  significant  investment  in 
genomic  research,  often  funded  through  public  programs  for  which  there  are  no  assurances  of  on-going  support.  Should  any 
government limit patent rights to specific genetic materials, private investment in this area could also be significantly curtailed. 
In  addition, the adoption  of  genetic  diagnostics is  dependent to a great  extent on the education  and training of  physicians and 
clinicians.  We  do  not  have  the  resources  to  undertake  such  training,  and  are  relying  on  larger  industry  participants  and 
professional medical colleges to establish, communicate and educate physicians and clinicians on best practices related to genetic 
diagnostics.  

We are subject to evolving legislative, judicial and ethical standards on use of technology and biotechnology.  

The adoption of genetic testing is occurring within the broader context of a myriad of decisions related to genetic patenting 
and genotyping. Issues associated with health insurance, data access, intellectual property protection, national and international 
legislative  initiatives  and  other  variables  may  have  a  significant  impact  on  the  wide  spread  adoption  of  genetic  testing  or  on 
specific segments or tests within the genetic testing market.  

29

                                   
   
 
 
 
 
 
 
 
 
 
 
 
 
Our success depends on our ability to attract and retain our management and staff.  

We depend on the principal members of our management and scientific staff, including our chief executive officer, Patrick 
Balthrop, and our operations, marketing, research and development, technical support, technical service and sales staff. The loss 
of services of key members of management could delay or reduce our product development, marketing and sales and technical 
support  efforts.  In  addition,  recruiting  and  retaining  qualified  scientific  and  other  personnel  to  perform  research  and 
development,  technical  support,  technical  service  and  marketing  and  sales  work  will  be  critical  to  our  success.  There  is  a 
shortage in our industry of qualified management and scientific personnel, and competition for these individuals is intense. There 
can  be  no  assurance  that  we  will  be  able  to  attract  additional  and  retain  existing  personnel  necessary  to  achieve  our  business 
objectives.  

Our stock price has been and is likely to continue to be volatile.  

The  trading  price  of  our  common  stock  has  been  and  is  likely  to  continue  to  be  highly  volatile  and  subject  to  wide 

fluctuations in price. This volatility is in response to various factors, many of which are beyond our control, including:  

•

•

•

•

•

•

•

•

•

•

  actual  or  anticipated  variations  in  quarterly  operating  results  from  historical  results  or  estimates  of  results  prepared  by

securities analysts; 

  announcements of technological innovations or new products or services by us or our competitors; 

  announcements by us of significant acquisitions, strategic partnerships, joint ventures or capital commitments; 

  conditions or trends in the life science, biotechnology and pharmaceutical industries;

  additions or departures of key personnel; 

  changes in financial estimates by securities analysts;

  general economic conditions and interest rates; 

  instability in the United States and other financial markets and the ongoing and possible escalation of unrest in the Middle

East, other armed hostilities or further acts or threats of terrorism in the United States or elsewhere; 

  sales of our common stock; and

  the potential adverse impact of the secondary trading of our stock on foreign exchanges which are subject to less regulatory
oversight than the NASDAQ Global Market, without our permission, and the activity of the market makers of our stock on
such exchanges, including the risk that such market makers may engage in naked short sales and/or other deceptive trading
practices which may artificially depress or otherwise affect the price of our common stock on the NASDAQ Global Market.

In  addition,  the  stock  market  in  general,  and  the  NASDAQ  Global  Market  and  the  market  for  technology  companies  in 
particular,  has  experienced  significant  price  and  volume  fluctuations  that  have  often  been  unrelated  or  disproportionate  to  the 
operating performance of those companies. Further, there has been particular volatility in the market prices of securities of life 
sciences  companies.  These  broad  market  and  industry  factors  may  seriously  harm  the  market  price  of  our  common  stock, 
regardless of our operating performance. In the past, following periods of volatility in the market price of a company’s securities, 
securities class action litigation has often been instituted. A securities class action suit against us could result in substantial costs, 
potential liabilities and the diversion of management’s attention and resources.  

Anti-takeover provisions in our certificate of incorporation, bylaws and stockholder rights plan and Delaware law could make 
a third party acquisition of us difficult.  

Our certificate of incorporation, bylaws and stockholder rights plan contain provisions that could make it more difficult for 
a third party to acquire us, even if doing so would be beneficial to our stockholders. We are also subject to certain provisions of 
Delaware law that could delay, deter or prevent a change in control of us. These provisions could limit the price that investors 
might be willing to pay in the future for shares of our common stock.  

30

                                   
   
 
 
 
 
 
 
 
 
 
ITEM 1B. UNRESOLVED STAFF COMMENTS  

None.  

ITEM 2. PROPERTIES  

Our  principal  research  and  development,  manufacturing  and  administrative  facilities  are  located  in  Austin,  Texas,  and 
consist of approximately 115,000 square feet of leased  space pursuant to a lease  agreement which expires April 30, 2015. We 
maintain an additional 10,384 square feet of leased office space in Oosterhout, Netherlands, approximately 27,000 square feet of 
leased office and manufacturing space primarily used by the assay segment in Toronto, Canada, approximately 3,500 square feet 
of leased  office space in Shanghai,  People’s Republic of China, and approximately 2,500 square feet of leased office space in 
Tokyo, Japan. We are currently expanding our manufacturing space in Austin, Texas to ensure that our facilities are adequate for 
our future needs.  

ITEM 3. LEGAL PROCEEDINGS  

On  July 24,  2009,  we  notified  Abbott  Molecular  Inc.  of  our  intent  to  convert  its  right  to  distribute  Luminex’s  xTAG®
Respiratory  Viral  Panel  from  exclusive  to  non-exclusive  on  a  worldwide  basis  under  the  Distribution  Agreement,  dated 
February 1,  2008,  between  Abbott  Molecular  and  LMD.  On  September 11,  2009,  Abbott  Molecular  Inc.  notified  us  that  it 
intended to exercise its right to seek arbitration under the Distribution Agreement. Among other matters, Abbott disputed LMD’s 
right to terminate Abbott’s exclusive right to distribute RVP under the Agreement. The arbitration to resolve this matter was held 
on  December 14-15,  2009.  The  arbitrator  issued  his  binding  ruling  on  December 30,  2009,  instructing  Luminex,  among  other 
matters,  to  reinstate  Abbott’s  exclusive  right  to  distribute  RVP  outside  of  the  United  States  and  co-exclusively  with  Fisher 
Scientific  within  the  United  States.  All  other  terms  and  conditions  of  the  Distribution  Agreement  remain  in  effect  and  are 
unaffected by the Arbitration.  

When  and  if  it  appears  probable  in  management’s  judgment  that  we  will  incur  monetary  damages  or  other  costs  in 
connection  with  any  claims  or  proceedings,  and  such  costs  can  be  reasonably  estimated,  liabilities  will  be  recorded  in  the 
financial statements and charges will be recorded against earnings. Though there can be no assurances, our management believes 
that the  resolution  of existing routine  matters  and other  incidental claims,  taking into  account  accruals  and insurance,  will  not 
have a material adverse effect on our financial condition or results of operations.  

ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS  

None.  

31

                                   
   
PART II  

ITEM 5.   MARKET  FOR  THE  REGISTRANT’S  COMMON  EQUITY,  RELATED  STOCKHOLDER  MATTERS  AND

ISSUER PURCHASES OF EQUITY SECURITIES

Market Information  

Our common stock is traded on the NASDAQ Global Market under the symbol “LMNX.”  

The  following  table  sets  forth  the  range  of  high  and  low  sale  prices  on  The  NASDAQ  Stock  Market  and/or  NASDAQ 
Global Market, as applicable, for each quarter during 2009 and 2008. On February 23, 2010, the last reported sale price of our 
common stock was $14.67 per share.  

2009
First Quarter 
Second Quarter 
Third Quarter 
Fourth Quarter 

2008
First Quarter 
Second Quarter 
Third Quarter 
Fourth Quarter 

Holders  

High

Low

$
$
$
$

$
$
$
$

22.83   
19.01   
18.70   
17.65   

High

20.48   
23.09   
27.00   
25.11   

$
$
$
$

$
$
$
$

14.86
14.32
14.47
12.75

Low

14.75
18.00
19.41
12.57 

As  of  February 23,  2010,  we  had  718  holders  of  record  of  our  common  stock.  Because  many  of  our  shares  are  held  by 
brokers  and other institutions on behalf of stockholders, we are unable  to estimate the  total number  of  beneficial stockholders 
represented by these record holders.  

Dividends  

We have never declared or paid cash dividends on our common stock and, while this policy is subject to periodic review by 
our  board  of  directors,  we  currently  intend  to  retain  any  earnings  for  use  in  our  business  and  do  not  anticipate  paying  cash 
dividends in the foreseeable future. Our ability to declare dividends may also from time to time be limited by the terms of any 
applicable credit facility.  

32

                                   
   
 
   
   
   
 
   
   
 
   
 
 
Performance Graph  

The following graph compares the change in Luminex’s cumulative total stockholder return on its common shares with the

NASDAQ Composite Index and the NASDAQ Biotechnology Index.  

COMPARISON OF 5 YEAR CUMULATIVE TOTAL RETURN* 
Among Luminex Corporation, The NASDAQ Composite Index 
And The NASDAQ Biotechnology Index  

*

  $100 invested on 12/31/04 in stock or index, including reinvestment of dividends. Fiscal year ending December 31.

Luminex Corporation 
NASDAQ Composite 
NASDAQ Biotechnology 

12/04  
100.00 
100.00       
100.00 

12/05
130.86
101.33       
117.54

12/06
143.02
114.01       
117.37

12/07      
182.88       
123.71       
121.37       

12/08      
240.54       
73.11       
113.41       

12/09
168.13
105.61 
124.58

33

                                   
  
   
 
 
 
   
       
         
         
         
         
         
 
 
   
   
     
     
     
Issuer Purchases of Equity Securities  

The stock repurchase activity for the fourth quarter of 2009 was as follows:  

Period
10/01/09 - 10/31/09 
11/1/09 - 11/30/09 
12/01/09 - 12/31/09 

Total Fourth Quarter 

 Total Number of   Average Price

Purchased as Part of

Shares that May Yet Be

Shares
Purchased

  Paid per Share   Publicly Announced   Purchased Under the Plans or 

(1)($)

Plans or Programs

Programs

Total Number of Shares Approximate Dollar Value of

—   
303   
993   
1,296   

—
13.74
14.63
14.42

—
—
—
—

—
—
—
—

(1)   Shares purchased are attributable to the withholding of shares by Luminex to satisfy the payment of tax obligations related

to the vesting of restricted shares.

34

                                   
   
 
    
     
 
 
    
     
 
 
 
 
  
  
  
  
   
 
 
 
 
 
 
 
 
 
 
 
  
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ITEM 6. SELECTED FINANCIAL DATA  

The  following  selected  consolidated  financial  data  should  be  read  in  conjunction  with  the  Consolidated  Financial 
Statements  and  Notes thereto  and with  Item 7  “Management’s Discussion  and Analysis  of Financial  Condition  and  Results  of 
Operations”  and  other  financial  data  included  elsewhere  in  this  Annual  Report  on  Form  10-K.  The  consolidated  statement  of 
operations data for the years ended December 31, 2009, 2008 and 2007 and the consolidated balance sheet data at December 31, 
2009 and 2008 are derived from the audited consolidated financial statements included elsewhere in this Annual Report on Form 
10-K.  The  consolidated  statement  of  operations  data  for  the  years  ended  December 31,  2006  and  2005  and  the  consolidated
balance sheet data at December 31, 2007, 2006 and 2005 are derived from audited consolidated financial statements not included 
in this Annual Report on Form 10-K.  

2009

Year Ended December 31,

2006
2007
2008
(In thousands, except per share data)

2005

Consolidated Results of Operations 

Data: 
Total revenue 
Gross profit 
Income (loss) from operations 
Net income (loss) 

Net income (loss) applicable to 

common stockholders 

Net income (loss) per common 

share, basic 

Shares used in computing net 

income (loss) per share, basic 

$

$

$

$

120,643   
81,294   
7,399   
17,729   

104,447   
70,946
3,353
3,057

$

75,010   
46,094
(17,418)
(2,711)

$

52,989 
32,252 

$

(581)[1] 
1,507[1]  

42,313 
22,321
(3,496)
(2,666)

17,729   

$

3,057

$

(2,711)

$

1,507 

$

(2,666)

0.44   

$

0.08   

$

(0.08)  

$

0.05[1]  

$

(0.09)

40,562   

37,868

34,361

31,434 

30,990

Net income (loss) per share, diluted

$

0.43   

$

0.08

$

(0.08)

$

0.05[1]  

$

(0.09)

Shares used in computing net 

income (loss) per share, diluted

41,633   

39,700

34,361

32,988 

30,990

2009

2008

At December 31,
2007
(In thousands)

2006

2005

Consolidated Balance Sheet Data: 

Cash and cash equivalents 
Short-term investments 
Long-term investments 
Working capital 
Total assets 
Total long-term debt 
Total stockholders’ equity 

$

90,843 
8,511 
20,228   

122,398 
248,013 
3,591 
218,738 

$

$

81,619
40,501

2,000   

$

27,233
6,944

—   

131,767
217,291
3,359
194,540

40,801
123,559
3,110
103,480

$

27,414   
10,956   
7,346   
44,179   
66,696   
—   
54,159   

25,206
10,947
5,466 
39,364
58,035
—
44,710

[1]   Effective  January 1,  2006,  we  changed  our  method  of  accounting  for  stock-based  compensation  to  conform  to  ASC  718 

“Stock Compensation”. 

35

                                   
   
 
   
   
 
 
   
 
 
 
   
   
   
 
 
 
 
   
   
 
 
   
  
   
   
 
 
   
   
   
 
 
   
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
  
   
   
 
 
   
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
  
   
   
 
 
   
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
  
   
   
 
 
   
 
 
 
  
   
   
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
  
   
   
 
 
   
 
 
 
 
 
   
   
   
   
   
   
   
   
   
 
 
 
 
   
 
  
   
 
 
   
   
   
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ITEM 7.   MANAGEMENT’S  DISCUSSION  AND  ANALYSIS  OF  FINANCIAL  CONDITION  AND  RESULTS  OF

OPERATIONS 

The following information should be read in conjunction with the Consolidated Financial Statements and the accompanying 
Notes  included  below  in  Item 8  and  “Risk  Factors”  included  above  in  Item 1A  of  this  Annual  Report  on  Form  10-K.  This 
discussion  contains  forward-looking  statements  that  involve  risks  and  uncertainties.  Our  actual  results  may  differ  materially 
from those anticipated in these forward-looking statements.  

Overview  

We develop, manufacture and sell proprietary biological testing technologies and products with applications throughout the 
life sciences and diagnostics industries. These industries depend on a broad range of tests, called bioassays, to perform diagnostic 
tests,  discover  and  develop  new  drugs  and  identify  genes.  Our  xMAP®  technology,  an  open  architecture,  multiplexing 
technology, allows simultaneous analysis of up to 500 bioassays from a small sample volume, typically a single drop of fluid, by 
reading biological tests on the surface of microscopic polystyrene beads called microspheres. xMAP technology combines this 
miniaturized  liquid  array  bioassay  capability  with  small  lasers,  digital  signal  processors  and  proprietary  software  to  create  a 
system offering advantages in speed, precision, flexibility and cost. Our xMAP technology is currently being used within various 
segments of the life sciences industry which includes the fields of drug discovery and development, clinical diagnostics, genetic 
analysis, bio-defense, protein analysis and biomedical research.  

Our  end  user  customers  and  partners,  which  include  laboratory  professionals  performing  research,  clinical  laboratories 
performing tests on patients as ordered by a physician and other laboratories, have a fundamental need to perform high quality 
testing as efficiently as possible.  Luminex has adopted a business model built, in part,  around  strategic partnerships. We have 
licensed our xMAP technology to partner companies, which in turn then develop products that incorporate the xMAP technology 
into  products  that  partners  sell  to  end  users.  Luminex  develops  and  manufactures  the  proprietary  xMAP  laboratory 
instrumentation  and  the  proprietary  xMAP  microspheres and sells  these products to its partners.  Our partners  then sell  xMAP 
instrumentation and xMAP-based reagent consumable products, which run on the instrumentation, to the end user laboratory. As 
of December 31, 2009, Luminex had approximately 68 strategic partners and these partners have purchased from Luminex over 
6,760 xMAP-based systems. Of the 68 strategic partners, 39 have released commercialized reagent-based products utilizing our 
technology.  

Beginning in 2006, we began developing proprietary assays through LBG. This development was supplemented in 2007 by 
our  acquisition  of  Tm  Bioscience,  which  we  now  refer  to  as  LMD.  Our  assay  segment  focuses  on  the  molecular  diagnostics 
market and certain specialty markets.  

Luminex has several forms of revenue that result from our business model:  

•

•

•

•

•

•

  System revenue is generated from the sale of our xMAP systems and peripherals. Currently, system revenue is derived
from the sale of the Luminex 100 and 200 analyzers, our FLEXMAP 3D system,  optional  XY Platform and  Sheath
Delivery Systems. 

  Consumable  revenue  is  generated  from  the  sale  of  our  dyed  polystyrene  microspheres  and  sheath  fluid.  Our  larger
commercial and development partners often purchase these consumables in bulk to minimize the number of incoming
qualification events and to allow for longer development and production runs.

  Royalty  revenue  is  generated  when  a  partner  sells  our  proprietary  microspheres  to  an  end  user,  a  partner  sells  a  kit
incorporating our proprietary microspheres to an end user or when a partner utilizes a kit to provide a testing result to a
user.  End users can be facilities such  as  testing labs, development facilities and research facilities that  buy prepared
kits and have specific testing needs or testing service companies that provide assay results to pharmaceutical research
companies or physicians. 

  Assay revenue is generated from the sale of our kits which are a combination of chemical and biological reagents and

our proprietary bead technology used to perform diagnostic and research assays on samples. 

  Service revenue is generated when a partner or other owner of a system purchases a service contract from us after the
standard  warranty  has  expired.  Service  contract  revenue  is  amortized  over  the  life  of  the  contract  and  the  costs
associated with those contracts are recognized as incurred. 

  Other  revenue  consists  of  items  such  as  training,  shipping,  parts  sales,  license  revenue,  grant  revenue,  contract
research  and development fees,  milestone revenue  and other items that  individually  amount to less  than 5% of total
revenue. 

36

                                   
   
 
 
 
 
 
 
2009 Highlights  

•

•

•

•

•

•

•

•

•

•

  Luminex grew total revenue by approximately 16% over 2008 revenue to $120.6 million 

  Gross margin percentage of 67%, compared to 68% in 2008

  For  the  year  ended  2009,  assay  revenue  increased  66%,  royalty  revenue  increased  23%  and  system  sales

increased 9% over the prior calendar year

  Full commercial launch of the high-throughput FLEXMAP 3D multiplexing system 

  System shipments of 873, resulting in cumulative life-to-date shipments of 6,767, up 15% from a year ago

  Our partners reported over $281 million of royalty bearing end user sales on xMAP technology for the year, an

18% increase over 2008 

  Settlement of SUNY lawsuit, resulting in a one-time charge of approximately $4.4 million 

  Establishment  of  offices  in  Shanghai,  People’s  Republic  of  China  and  Tokyo,  Japan  to  provide  commercial

support and service to customers and partners in these markets

  Obtained  registration  certificate  from  the  People’s  Republic  of  China  for  the  Luminex  100  and  Luminex  200

Systems 

  Tax  benefit  from the  release  of  the  U.S.  deferred tax  asset  valuation  allowance  provided  a  one  time  benefit  of

$14.9 million, or $0.36 per share, basic 

Consumable Sales Trends  

We  have  experienced  a  decline  in  consumable  revenue  since  the  third  quarter  of  2008.  After  thorough  analysis  of  the 
decline, we have identified several factors contributing to the decline, none of which individually appear to be systemic in nature 
or  indicative  of  future  results.  Overall,  the  decline  manifested  itself  through  a  decline  in  activity  at  varying  times  from  our 
largest,  bulk  purchasing  partners.  From  the  third  quarter  of  2008  through  the  fourth  quarter  of  2009,  we  had  bulk  purchases 
totaling  $7.0 million,  $6.8 million,  $6.1 million,  $5.5 million,  $4.3  million,  and  $6.4 million  in  consumables,  respectively. 
Alternatively,  non  bulk  consumable  sales  varied  within  a  much  smaller  range  between  $1.2 million  and  $1.8 million  with  the 
largest  amount  of  non  bulk  sales  taking  place  in  the  third  quarter  of  2009  with  $1.8 million  of  consumables.  We  believe  the 
decrease in bulk purchases can be attributed to several factors including (1) purchases in prior periods of significant volumes of 
consumables related to the conversion of our partners’ assay product portfolios from carboxyl beads to magnetic beads primarily 
in anticipation of the release of our new MagPix system in 2010; (2) volume reductions in bulk purchases from several of our 
partners as a result of a reduction in total consumable needs prior to the regulatory clearance and commercialization phases of 
development of new products and transitioning product lines; (3) increased attention on inventory management by our partners 
during 2009 as a result of the macro economic climate and (4) an increase in our partners’ focus on generating current revenue 
from  commercialized  products.  We  anticipate  consumables  sales  will  improve  in  2010.  The  success  of  our  partners’
commercialization efforts  is  reflected  in the  rising  level  of  royalties and reported  royalty  bearing  sales during  the  period  over 
which the consumable revenue has declined. Reported royalty bearing sales have increased by 18% from $238.5 million in 2008 
to $281.8 million in 2009.  

Release of Valuation Allowance  

During  the  fourth  quarter  of  2009,  we  released  a  portion  of  our  total  valuation  allowance  on  deferred  U.S.  tax  assets. 
Release  of  the  valuation  allowance  was  dependent  upon  an  assessment  of  the  likelihood  of  utilization  of  the  specifically 
identified deferred tax assets. The assessment indicated that Luminex was more likely than not to benefit from the deferred tax 
assets based upon our historical pre-tax book income and projected taxable income, thus prompting the release. The tax benefit 
from the release of this deferred tax asset valuation allowance is reflected below operating income as a benefit of $14.9 million 
in 2009, or $0.36 per share, basic.  

As a result of the release of our valuation allowance on US tax assets, our effective tax rate, which has been relatively low, 
will increase significantly in the near term. For 2010, we estimate that our effective tax rate will be in excess of the maximum 
U.S. corporate tax rate of 35%, however, for the full year 2010, we expect cash taxes paid will be less than 25% of total income 
tax expense recognized for the full year. The quarterly effective tax rate for 2010 will fluctuate as a result of variability of the 
taxable  income  within  the  multiple  jurisdictions  (the  United  States,  Canada,  The  Netherlands,  China  and  Japan)  in  which  we 
operate.  

37

  
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Change in Cash Position  

Our cash, cash equivalents and investments decreased by approximately $4.5 million during the year ended December 31, 
2009  to  $119.6 million  at  December 31,  2009  from  $124.1 million  at  December  31,  2008.  The  decrease  was  primarily 
attributable to capital expenditures of $10.4 million partially offset by positive operating cash flows.  

Segment Information  

Luminex has two reportable segments: The technology segment and the assay segment. The technology segment, which is 
our base business, consists of system sales to partners and end customers, raw bead sales, royalties, service and support of the 
technology, and other miscellaneous items. The assay segment consists of LBG and LMD. This segment is primarily involved in 
the development and sale of assays on xMAP technology for use on Luminex’s installed base of systems.  

Future Operations  

We  anticipate 2010 revenue growth to  be  driven  by  continued  adoption of our core  technology coupled  with system and 
assay introductions and commercialization by Luminex and our partners. We anticipate continued revenue concentration in our 
high  margin  items  (assays,  consumables  and  royalties)  contributing  to  favorable,  but  variable  gross  margin  percentages. 
Additionally,  we  believe  that  a  sustained  investment  in  R&D  is  necessary  in  order  to  meet  the  needs  of  our  marketplace  and 
provide a sustainable new product pipeline. Therefore, we estimate that R&D expenditures will increase in absolute dollars over 
time,  but  decrease  as  a  percentage  of  total  revenue  towards  our  long  term  target  of  15%  of  revenue.  We  could  experience 
volatility  in  R&D  expenses  as  a  percentage  of  revenue  on  a  quarterly  basis.  Consistent  with  this  trend  our  R&D  expenses 
increased by $2.1 million or 11% from 2008 to 2009, but dropped as a percentage of total revenue to 17% in 2009 compared to 
18% in 2008. While we currently expect modest increases in absolute dollars of selling, general, and administrative expenses in 
2010,  excluding  the  impact  of  foreign  exchange  rates  on  foreign  denominated  balances,  we  expect  selling,  general,  and 
administrative expenses to decrease as a percentage of total revenue in 2010.  

We expect our primary challenges in 2010 to be the continued adoption and development of partner products incorporating 
Luminex technology, the timing effect of the ongoing uncertainty in global finance markets and changes in government funding 
on  planned  purchases  by  end  users,  commercialization,  regulatory  acceptance  and  market  adoption  of  output  from  the  assay 
segment  and  the  expansion  and  enhancement  of  our  installed  base  and  leadership  position  within  our  identified  target  market 
segments.  

Critical Accounting Policies  

The discussion and analysis of our financial condition and results of operations are based upon our consolidated financial 
statements, which have been prepared in accordance with United States generally accepted accounting principles (GAAP). The 
preparation of these financial statements requires us to make estimates and judgments that affect the reported amounts of assets, 
liabilities, revenues and expenses, and related disclosure of contingent assets and liabilities. We base our estimates on historical 
experience  and  on  various  other  assumptions  that  are  believed  to  be  reasonable  under  the  circumstances,  the  results  of  which 
form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other 
sources. The following is a discussion of our most critical accounting policies used in the preparation of our financial statements, 
and  the  judgments  and  estimates  involved  under  each.  We  also  have  other  significant  accounting  policies  that  do  not  involve 
critical  accounting  estimates  because  they  do  not  generally  require  us  to  make  estimates  and  judgments  that  are  difficult  or 
subjective.  These  are  described  in  Note  1  of  our  Consolidated  Financial  Statements  provided  herein  in  Item 8.  Estimates  and 
assumptions are reviewed periodically. Actual results may differ from these estimates under different assumptions or conditions. 

38  

                                   
   
Revenue  Recognition.  Revenue  on  sales  of  our  products  is  recognized  when  persuasive  evidence  of  an  agreement  exists, 
delivery has occurred, the fee is fixed and determinable and collectability is probable. These criteria are generally met at the time 
our product is shipped. If the criteria for revenue recognition are not met at the time of shipment, the revenue is deferred until all 
criteria  are  met.  Royalty  revenue  is  generated  when  a  partner  sells  products  incorporating  our  technology,  provides  testing 
services to third parties using our technology or resells our consumables. Royalty revenue is recognized as it is reported to us by 
our  partners,  generally  quarterly; therefore,  the  underlying end  user  sales  may  be  related  to  prior periods  due to the  timing of 
when the revenue is reported to us by our partners. We also sell extended service contracts for maintenance and support of our 
products.  Revenue  for  service  contracts  is  recognized  ratably  over  the  term  of  the  agreement.  Revenue  from  contracts  with 
multiple elements is recognized as each element is earned based on the relative selling price of each element when there are no 
undelivered elements that are essential to the functionality of the delivered elements and when the amount is not contingent upon 
delivery of the undelivered elements.  

Upfront payments from our strategic partners are nonrefundable and will be recognized as revenue as our strategic partners 
purchase products or applied against royalty payments. Nonrefundable license fees are amortized into revenue over the estimated 
life of the license agreements.  

Inventory  Valuation.  Inventories  are  valued  at  the  lower  of  cost  or  market  value,  with  cost  determined  according  to  the 
standard cost method. Inventories have been written down through an  allowance for excess and obsolete  inventories. The  two 
major components of the allowance for excess and obsolete inventory are (i) a specific write-down for inventory items that we no 
longer  use  in  the  manufacture  of  our  products  or  that  no  longer  meet  our  specifications  and  (ii) a  write-down  against  slow 
moving items for potential obsolescence. Inventory is reviewed on a regular basis and adjusted based on management’s review 
of inventories on hand compared to estimated future usage and sales. While management believes that adequate write-downs for 
inventory  obsolescence  have  been  made  in  the  consolidated  financial  statements,  scientific  and  technological  advances  will 
continue and we could  experience additional inventory write-downs in the future. However, we  do not believe this estimate is 
subject to significant variability.  

Warranties.  We  provide  for  the  estimated  cost  of  initial  product  warranties  at  the  time  revenue  is  recognized.  While  we 
engage  in  product  quality  programs  and processes,  our  warranty obligation  is affected  by  product  failure  rates, material usage 
and service delivery  costs incurred in  correcting  a product failure. While management believes  that adequate reserve has been 
made  in  the  consolidated  financial  statements  for  product  warranties,  should  actual  product  failure  rates,  material  usage  or 
service delivery costs differ from our estimates, revisions to the estimated warranty liability would be required. However, we do 
not believe this estimate is subject to significant variability.  

Purchase Price Allocation, Intangibles and Goodwill. The purchase price allocation for acquisitions requires extensive use 
of accounting estimates and judgments to allocate the purchase price to the identifiable tangible and intangible assets acquired, 
including in-process research and development (IPR&D), and liabilities assumed based on their respective fair values. Intangible 
assets  with  definite  lives  are  amortized  over  the  assets’  estimated  useful  lives using  the  straight-line  method.  We  periodically 
review the estimated useful lives of our identifiable intangible assets, taking into consideration any events or circumstances that 
might result in a diminished fair value or revised useful life.  

We evaluate the carrying value of goodwill and other intangible assets annually or more frequently if there is evidence that 
certain  events  or  changes  in  circumstances  indicate  that  the  carrying  amount  of  these  assets  may  not  be  recoverable.  In 
performing  the  impairment  test,  we  utilize  the  two-step  approach  prescribed  under  U.S.  GAAP.  The  first  step  requires  a 
comparison of the carrying value of the reporting unit to the estimated fair value of the reporting unit. If in step one of the annual 
test, the carrying amount of a reporting unit exceeds its fair value, then a goodwill impairment test is performed in step two to 
measure  the  amount  of  the  impairment  loss,  if  any.  We  would  recognize  an  impairment  charge  for  any  amount  by  which  the 
carrying  amount  of  goodwill  exceeds  its  fair  value.  Determining  the  fair  value  of  goodwill  is  subjective  in  nature  and  often 
involves the use of estimates and assumptions.  

As of  December 31,  2009, we  have  $39.6 million  of goodwill  allocated  to  the  assay segment, which  includes LMD.  Our 
annual test did not result  in an impairment charge  as  the  estimated  fair  value of the assay  segment  reporting  unit continues  to 
exceed  the  carrying  value  by  a  significant  enough  amount  that  any  reasonably  likely  change  in  the  assumptions  used  in  the 
analysis, including terminal growth rates and the discount rate, would not cause the carrying value to exceed the estimated fair 
value for the reporting unit as determined under the step one goodwill impairment analysis.  

39

                                   
   
We utilize the income approach based on a discounted cash flow analysis to determine its fair value estimates, and then use 
market  comparisons  as  a  reasonability  check  to  ensure  that  neither  the  income  approach  nor  the  market  comparisons  yielded 
significantly different results. The  income  approach is  based  on a discounted  cash flow (DCF) analysis and  calculates  the fair 
value  by  estimating  the  after-tax  cash  flows  attributable  to  a  reporting  unit  and  then  discounting  the  after-tax  cash  flows  to  a 
present  value  using  a  risk-adjusted  discount  rate.  As  our  assay  segment  and  goodwill  came  into  existence  in  2007  due  to  our 
acquisition of Tm Biosciences, now referred to as LMD, we believe that the DCF method best aligns with how we approached 
the  acquisition  and  determined  the  value  of  the  acquired  company.  This  methodology  used  to  determine  fair  value  has  been 
consistently applied since the inception of our goodwill in 2007; however, the assumptions and estimates are updated each year. 
Our estimates are based on revenue projections by product line, and include judgment based on historical growth and scheduled 
product  approvals  by  the  various  governmental  authorities.  We  believe  its  assumptions  are  consistent  with  the  plans  and 
estimates  used  to  manage  the  underlying  businesses.  The  most  significant  assumptions  used  in  the  discounted  cash  flow 
methodology are the discount rate, based upon the estimated weighted average cost of capital (WACC), and the terminal growth 
rate, based upon strategic studies we commissioned and our own internal analysis. We used the following rates in 2009:  

Assumptions
WACC 
Terminal Growth Rate 

2009

15.2%
4.4%

To determine our WACC rate, we performed a peer company analysis and considered the weighted average return on debt 
and equity, the  updated risk-free  interest  rate, beta,  equity  risk  premium, and  entity specific size  risk  premium. We  based our 
terminal growth rates upon market estimates provided in strategic studies previously commissioned by us and our own internal 
analysis. Our analysis yielded an estimated fair value in excess of the carrying value by over 50% for 2009.  

Concurrent with the above analysis, we performed a sensitivity analysis based upon reasonably likely changes to determine 
if our DCF analysis would result in impairment if the following changes were made to our assumptions: i) assumed WACC rate 
was  increased  by  5 percentage  points;  ii)  future  revenue  was  75%  of  our  projections  in  the  DCF  model;  or  iii)  the  terminal 
growth rate  used  was  50%  lower.  None of  these sensitivity  analyses  resulted  in  an  estimated  fair  value less  than the  carrying 
amount of the reporting unit.  

Accounting  for  Income  Taxes.  We  calculate  our  provision  for  income  taxes  using  the  asset  and  liability  method,  under 
which  deferred  tax  assets  and  liabilities  are  recognized  by  identifying  the  temporary  differences  arising  from  the  different 
treatment  of  items  for  tax  and  accounting  purposes.  In  determining  the  future  tax  consequences  of  events  that  have  been 
recognized  in  our  financial  statements  or  tax  returns,  judgment  is  required.  Differences  between  the  anticipated  and  actual 
outcomes of these future tax consequences could have  a material impact  on our consolidated results of operations or financial 
position.  The  recognition  of  deferred  tax  assets  is  reduced  by  a  valuation  allowance  if  it  is  more  likely  than  not  that  the  tax 
benefits will not be realized. We regularly review our deferred tax assets for recoverability and establish a valuation allowance 
based on historical income, projected future income, the expected timing of the reversals of existing temporary differences and 
the  implementation  of  tax-planning  strategies.  Undistributed  earnings  of  our  foreign  subsidiaries  are  considered  permanently 
reinvested and, accordingly, no provision for U.S. federal or state income taxes has been provided thereon.  

Effective  January 1,  2007, we  adopted Accounting  Standards  Codification  (ASC) 740  “Income  Taxes”  (ASC 740) which 
clarifies the accounting for uncertainty in tax positions. These provisions require recognition of the impact of a tax position in 
our financial statements only if that position is more likely than not of being sustained upon examination by taxing authorities, 
based  on  the  technical  merits  of  the  position.  Any  interest  and  penalties  related  to  uncertain  tax  positions  will  be  reflected  in 
income tax expense. Determining the consolidated provision for income taxes involves judgments, estimates and the application 
of complex tax regulations. We are required to provide for income taxes in each of the jurisdictions where we operate, including 
estimated liabilities for uncertain tax positions. Although we believe that we have provided adequate liabilities for uncertain tax 
positions,  the  actual  liability  resulting  from  examinations  by  taxing  authorities  could  differ  from  the  recorded  income  tax 
liabilities and could result in additional income tax expense. In accordance with ASC 740, changes of estimates in our income 
tax liabilities are reflected in our income tax provision in the period in which the factors resulting in the change to our estimate 
become known to us. As a result, our effective income tax rate may fluctuate on a quarterly basis.  

40  

                                   
   
 
 
   
 
 
 
 
 
We  recognize  excess  tax  benefits  associated  with  share-based  compensation  to  stockholders’  equity  only  when  realized. 
When assessing whether excess tax benefits relating to share-based compensation have been realized, we follow the with-and-
without approach, excluding any indirect effects of the excess tax deductions. Under this approach, excess tax benefits related to 
share-based compensation are not deemed to be realized until after the utilization of all other tax benefits available to us.  

Stock compensation. Stock-based compensation cost is measured at the grant date based on the fair value of the award and 
is recognized as an expense on a straight-line basis over the requisite service period, which is generally the vesting period. The 
fair  value  of  our  stock-based  awards  is  estimated  using the  Black-Scholes  option  pricing  model.  The  Black-Scholes  valuation 
calculation  requires  us  to  estimate  key  assumptions  such  as  expected  volatility,  expected  term  and  risk-free  rate  of  return. 
Calculation of expected volatility is based on historical volatility. The expected term is calculated using the contractual term of 
the options as well as an analysis of our historical exercises of stock options. The estimate of risk-free rate is based on the U.S. 
Treasury yield curve in effect at the time of grant. We have never paid cash dividends and do not currently intend to pay cash 
dividends, thus we have assumed a 0% dividend yield. We are required to estimate potential forfeitures of stock grants and adjust 
compensation  cost  recorded  accordingly.  The  estimate  of  forfeitures  is  based  on  historical  forfeiture  performance  and  will  be 
adjusted over the requisite service period to the extent that actual forfeitures differ, or are expected to differ, from such estimates. 
If we use different assumptions for estimating stock-based compensation expense in future periods or if actual forfeitures differ 
materially  from  our  estimated  forfeitures,  the  change  in  our  stock-based  compensation  expense  could  materially  affect  our 
operating income, net income, and net income per share.  

Consolidated Results of Operations  

The following table sets forth the percentage of total revenue of certain items in the Consolidated Statements of Operations. 
The  financial information and  the discussion below  should be read in conjunction with the Consolidated  Financial Statements 
and Notes thereto.  

2009

Year Ended December 31,
2008

2007

Revenue 

Cost of revenue 

Gross profit 

Operating expenses 

Research and development expense 
Selling, general and administrative expense 
In-process research and development expense 
Gain on settlement of liability 

Total operating expenses 

Income (loss) from operations 

Interest expense from long-term debt

Other income, net 

Settlement of litigation 

Income taxes 

Net income (loss) 

41

100%

33%

67%

17%  
44%
—
—

61%

6%

—

1%

(4)%

12%

15%

100%  

32%  

68%  

18%  
47%  
— 
— 

65%  

3%  

— 

1%  

— 

(1)% 

3%  

100%

39%

61%

20%
54%
10%
(3)%

82%

(20)%

(1)%

2%

15%

—

(4)%

                                   
   
 
 
 
   
 
 
 
 
 
 
 
 
 
 
  
 
 
   
 
   
 
 
 
 
 
 
 
 
  
 
 
   
 
   
 
   
 
 
 
   
  
 
 
   
 
 
   
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
  
 
 
   
 
   
 
 
 
 
 
 
 
 
  
 
 
   
 
  
 
 
   
 
 
  
 
 
   
 
  
 
   
 
 
   
 
 
   
 
 
 
  
 
 
   
 
   
 
 
 
 
 
 
 
 
  
 
 
   
 
   
 
 
 
 
 
 
 
 
Year Ended December 31, 2009 Compared to Year Ended December 31, 2008  

Year Ended December 31,

Revenue 
Gross profit 
Gross margin percentage 
Operating expenses 
Net income 

2009

$
$

$
$

120,643
81,294 

67%

73,895
17,729

$
$

$
$

Variance  

2008
(dollars in thousands)
104,447
70,946 

$
$

16,196 
10,348 

68%

67,593
3,057

(1)% 

$
$

6,302 
14,672 

Variance
(%)

16%
15%

N/A

9%
480%

Revenue.  Total  revenue  increased  to  $120.6 million  for  the  year  ended  December 31,  2009  from  $104.4 million  in  2008. 
The  increase  in  revenue  was  primarily  attributable  to  an  increase  of  $12.3  million  in  assay  revenue  in  the  assay  segment  and 
continued  growth in  system  sales  and  royalty revenue  in  the  technology  segment,  offset by  a  decrease  in technology  segment 
consumable sales.  

A breakdown of revenue for the years ended December 31, 2009 and 2008 is as follows (in thousands):  

System sales 
Consumable sales 
Royalty revenue 
Assay revenue 
Service contracts 
Other revenue 

Year Ended December 31,

2009

2008

$

$

30,711   
28,380   
18,312   
31,054   
5,845   
6,341   
120,643   

$

$

28,136
31,724
14,897
18,715
5,363
5,612 
104,447

We continue to have revenue concentration in a limited number of strategic partners, as the top five customers, by revenue, 
accounted for 48% of total revenue in 2009 down from 53% of total revenue in 2008. In particular, two customers accounted for 
26% of 2009 total revenue (15% and 11% respectively) down from 36% of 2008 total revenue (19% and 17% respectively). The 
decline was primarily attributable to the increase in assay segment revenue as a percentage of total revenue, but was also affected 
by company and market factors specific to those customers. No other customer accounted for more than 10% of total revenue. 
See the segment discussions that follow on pages 45-51 for additional revenue discussion.  

Gross Profit. Gross profit increased to $81.3 million for the year ended December 31, 2009, as compared to $70.9 million 
for the year ended December 31, 2008. The gross profit margin rate (gross profit as a percentage of total revenue) was 67% for 
the  year  ended  December 31,  2009,  down  from  68%  for  the  year  ended  December 31,  2008.  Maintenance  of  our  gross  profit 
margin rate was enabled by the high concentration of sales in our higher margin items such as assays, consumables and royalties. 
The increase in gross profit was primarily attributable to the overall increase in revenue. We anticipate continued fluctuation in 
gross profit margin and related gross profit primarily as a result of variability in partner bulk purchases and the absolute number 
of quarterly system sales.  

Research  and  Development  Expense.  Research  and  development  expenses  increased  to  $20.8 million  for  the  year  ended 
December 31,  2009  from  $18.6 million  for  the  year  ended  December 31,  2008.  The  increase  was  primarily  attributable  to 
increased activity by the assay segment related to product development, an increase in materials, and additional personnel costs 
associated with the addition of employees and contract employees. Research and development headcount at December 31, 2009 
was 132 as compared to 116 at December 31, 2008. As a percentage of revenue, research and development expense decreased to 
17% in 2009 as compared with 18% in 2008. Our current expectation is for research and development expenses to be between 
15% and 18% of total revenue for 2010.  

42  

                                   
   
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
   
 
 
 
 
 
 
 
   
 
 
 
 
 
 
  
   
 
 
 
 
 
 
Selling, General and  Administrative  Expense.  Selling,  general  and  administrative  expenses  increased  to  $53.1 million  for 
the year ended December 31, 2009 from $49.0 million for the comparable period in 2008. The increase was primarily attributable 
to additional personnel costs associated with the addition of employees and an increase in stock compensation expense. Selling, 
general and administrative headcount at December 31, 2009 was 158 as compared to 134 at December 31, 2008. As a percentage 
of revenue, selling, general and administrative expenses decreased to 44% in 2009 as compared to 47% in 2008.  

Income from Operations. Operating profit as a percentage of revenue increased from 3% in 2008 to 6% in 2009 as a result 

of our overall control of operating expenses and maintenance of our gross profit margin rate.  

Other Income, net. Other income, net decreased to $0.7 million for the year ended December 31, 2009 from $1.1 million for 
the year ended December 31, 2008 due to the decrease in the average rate earned on our current invested balances from 2.0% for 
the  year  ended  December 31,  2008  to  0.6%  for  the  year  ended  December 31,  2009.  This  decrease  is  the  result  of  an  overall 
decrease in market rates compared to the prior year period.  

Income taxes. Income tax expense decreased in 2009 due to the $14.9 million tax benefit from the release of a portion of 

our total valuation allowance on deferred U.S. tax assets.  

Year Ended December 31, 2008 Compared to Year Ended December 31, 2007  

Revenue 
Gross profit 
Gross margin percentage 
Operating expenses 
Net (loss) income 

Year Ended December 31,

2008

2007
(dollars in thousands)

Variance  

$
$

$
$

104,447
70,946

68%

67,593
3,057

$
$

$
$

75,010
46,094

61%

63,512
(2,711)

$
$

$
$

29,437 
24,852 

7% 

4,081 
5,768 

Variance
(%)

39%
54%

N/A

6%
213%

Revenue. Total revenue increased to $104.4 million for the year ended December 31, 2008 from $75.0 million in 2007. The 
increase  in  revenue  was  primarily  attributable  to  an  increase  of  $17.2  million  in  consumable  and  royalty  revenues  in  the 
technology segment  and  continued growth in the  assay  segment, including the  effects  of  the acquisition  of LMD.  In addition, 
system sales increased to 915 systems in 2008 from 862 systems for 2007.  

A breakdown of revenue for the years ended December 31, 2008 and 2007 is as follows (in thousands):  

System sales 
Consumable sales 
Royalty revenue 
Assay revenue 
Service contracts 
Other revenue 

Year Ended December 31,

2008

2007

$

$

28,136   
31,724   
14,897   
18,715   
5,363   
5,612   
104,447   

$

$

24,428 
19,199
10,244
11,323
4,431
5,385
75,010

The top five customers, by revenue, accounted for 53% of total revenue in 2008. In particular, two customers accounted for 
36%  of  2008  total  revenue (19%  and  17%  respectively). No  other customer  accounted  for more  than  10%  of total revenue  in 
2008. See the segment discussions that follow on pages 45-51 for additional revenue discussion.  

Gross Profit. Gross profit increased to $70.9 million for the year ended December 31, 2008, as compared to $46.1 million 
for the year ended December 31, 2007. The gross profit margin rate was 68% for the year ended December 31, 2008, up from 
61% the year ended December 31, 2007. The increase in gross margin rate was primarily attributable to the continuing shift in 
revenue concentration towards higher margin items such as assays, consumables and royalties. The increase in gross profit was 
primarily attributable to the overall increase in revenue.  

43  

                                   
   
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
   
 
 
 
 
 
 
   
 
 
 
 
 
 
  
   
 
 
 
 
 
 
Research  and  Development  Expense.  Research  and  development  expenses  increased  to  $18.6 million  for  the  year  ended 
December 31,  2008  from  $15.4 million  for  the  year  ended  December 31,  2007.  The  increase  was  primarily  attributable  to 
incorporation of the results of LMD for the full twelve months in 2008 compared to the inclusion of only ten months of operating 
results  of  LMD in the year ended December 31, 2007, as the acquisition was consummated on  March 1, 2007, and to a lesser 
extent,  to  increased  activity  by  the  assay  segment  related  to  product  development,  an  increase  in  materials,  and  additional 
personnel  costs  associated  with  the  addition  of  employees  and  contract  employees.  Research  and  development  headcount  at 
December 31, 2008 was 116 as compared to 111 at December 31, 2007. As a percentage of revenue, research and development 
expense decreased to 18% in 2008 as compared with 21% in 2007.  

Selling, General and  Administrative  Expense.  Selling,  general  and  administrative  expenses  increased  to  $49.0 million  for 
the year ended December 31, 2008 from $40.7 million for the comparable period in 2007. The increase was primarily attributable 
to  incorporation  of  the  results  of  LMD  for  the  full  twelve  months  in  2008  compared  to  the  inclusion  of  only  ten  months  of 
operating results of LMD in the year ended December 31, 2007, and to a lesser extent additional personnel costs associated with 
the  addition  of  employees  and  an  increase  in  stock  compensation  expense.  Selling,  general  and  administrative  headcount  at 
December 31,  2008  was  134  as  compared  to  119  at  December 31,  2007.  As  a  percentage  of  revenue,  selling,  general  and 
administrative expenses reduced to 47% in 2008 as compared to 54% in 2007.  

Other Income, net. Other income, net decreased to $1.1 million for the year ended December 31, 2008 from $1.7 million for 
the year ended December 31, 2007 partially due to approximately $480,000 in costs related to a potential acquisition that did not 
occur,  offset  by  the  interest  income  on  the  net  proceeds  from  our  secondary  offering.  In  addition,  the  average  rate  earned  on 
current invested balances decreased to 2.0% for the year ended December 31, 2008 from 5.0% for the year ended December 31, 
2007.  This  decrease  in  the  average  rate  earned  is  the  result  of  an  overall  decrease  in  market  rates  compared  to  the  prior  year 
period. See additional discussions by segment below.  

Settlement of litigation. We settled our pending litigation with Rules Based Medicine (RBM) on October 15, 2007. As part 
of  the  settlement,  Luminex  received  a  cash  payment  of  $12.5 million.  $11.5 million  was  recognized  as  part  of  net  income  in 
2007, while $1.0 million was deferred for licensing rights granted to RBM from Luminex.  

Gain on settlement of liability. $2.3 million was recognized in the year ended December 31, 2007 related to the settlement 

of a liability related to the renegotiation of a contract acquired as part of the acquisition of Tm Bioscience.  

44

                                   
   
Segment Results of Operations  

Technology Segment  

Selected financial data for the year ended December 31, 2009 and 2008 of our technology segment is as follows:  

Revenue 
Gross profit 
Gross margin percentage 
Operating expenses 
Net income 

Year Ended December 31,

2009

2008
(dollars in thousands)

Variance  

$
$

$
$

87,389
57,649

66%

49,527
21,406

$
$

$
$

83,567
54,756

66%

45,723
9,405

$
$

$
$

3,822 
2,893 

0% 

3,804 
12,001 

Variance
(%)

5%
5%

N/A

8%
128%

Revenue. Total revenue increased 5% to $87.4 million for the year ended December 31, 2009 from $83.6 million in 2008. 
The increase in revenue was primarily attributable to an increase in system sales and royalty revenue as a result of the continued 
acceptance and utilization of our technology in the marketplace offset by decreases in consumable sales.  

A  breakdown  of  revenue  in  the  technology  segment  for  the  years  ended  December 31,  2009  and  2008  is  as  follows  (in 

thousands):  

System sales 
Consumable sales 
Royalty revenue 
Service contracts 
Other revenue 

Year Ended December 31,

2009

2008

$

$

29,296   
28,316   
18,312   
5,552   
5,913   
87,389   

$

$

26,408
31,678
14,897 
5,290
5,294
83,567 

The top five customers, by revenue, accounted for 56% of total technology segment revenue in 2009 compared to 62% in 
2008. In particular, two customers accounted for 37% of total technology segment revenue in the year ended December 31, 2009 
(21%  and  16%,  respectively).  For  comparative  purposes,  these  same  two  customers  accounted  for  45%  of  total  technology 
segment revenue (24% and 21%, respectively) in the year ended December 31, 2008. We believe that the decrease in percentage 
of total revenue represented by our two largest customers is primarily the result of specific company factors and general market 
factors applicable to our two largest  customers.  These  factors, we believe,  resulted in a decrease in the dollar amount  of  bulk 
purchases by one of our largest customers, and a decline in system purchases relative to their historical purchases by the other. 
No other customer accounted for more than 10% of total technology segment revenue.  

System  and  peripheral  component  sales  increased  11%  to  $29.3 million  for  the  year  ended  December 31,  2009  from 
$26.4 million for the year ended December 31, 2008. The technology segment sold 838 of the 873 total system sales in 2009. For 
the year ended December 31, 2009, five of our partners accounted for 552, or 66%, of total technology segment system sales for 
the  period.  Five  of  our  partners  accounted  for  698,  or  80%,  of  total  technology  segment  system  sales  for  the  year  ended 
December 31, 2008.  

45

                                   
   
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
   
 
  
   
   
 
 
 
 
 
 
   
 
   
 
   
  
 
   
 
 
 
 
 
 
Consumable  sales,  comprised  of  microspheres  and  sheath  fluid,  decreased  11%  to  $28.3 million  during  2009  from 
$31.7 million in 2008. This is primarily the result of a decrease in the number and average dollar amount of bulk purchases as 
described  in  the  Overview  section  above.  During  2009  we  had  51  bulk  purchases  of  consumables  totaling  approximately 
$22.3 million as compared with 49 bulk purchases totaling approximately $26.1 million in the prior year. Partners who reported 
royalty bearing sales accounted for $22.7 million, or 80%, of total consumable sales for the year ended December 31, 2009. A 
bulk  purchase  is  defined  as  the  purchase  of  $100,000  or  more  of  consumables  in  a  quarter.  As  the  number  of  applications 
available  on  our  platform  expands,  we  anticipate  that  the  overall  level  of  consumable  sales,  and  related  bulk  purchases,  will 
continue to fluctuate.  

Royalty  revenue  increased  23%  to  $18.3 million  for  the  year  ended  December 31,  2009  from  $14.9  million  for  the  year 
ended  December 31,  2008.  We  believe  this  is  primarily  the  result  of  our  increased  cumulative  instrument  placements,  menu 
expansion, and utilization of our partners’ assays on our technology. We expect modest fluctuations in the number of commercial 
partners  submitting  royalties  quarter  to  quarter  based  upon  the  varying  contractual  terms,  consolidations  among  partners, 
differing reporting and payment requirements, and the addition of new partners. For the year ended December 31, 2009, we had 
39  commercial  partners  submit  royalties  as  compared  with  35  for  the  year  ended  December 31,  2008.  Additionally,  the  39 
partners  from  whom  we  recognized  $18.3  million  in  royalties  in  2009  represented  approximately  $14.9 million  of  the  total 
royalties in 2008, an increase of approximately 23% over their prior year payments. Total royalty bearing sales reported to us by 
our  partners  were  approximately  $281.8 million  for the  year  ended  December 31,  2009  as  compared  to  $238.5 million  for  the 
year ended December 31, 2008.  

Service  contracts,  comprised  of  extended  warranty  contracts  earned  ratably  over  the  term  of  a  contract,  increased  5%  to 
$5.6 million during 2009 from $5.3 million in 2008. This increase is attributable to additional resources allocated to the sale of 
extended service  agreements  resulting in  increased penetration of the expanded installed base.  At  December 31, 2009, we had 
1,086  Luminex  systems  covered  under  extended  service  agreements  and  $2.3 million  in  deferred  revenue  related  to  those 
contracts. At December 31, 2008, we had 967 Luminex systems covered under extended service agreements and $2.1 million in 
deferred revenue related to those contracts.  

Other revenue, comprised of training revenue, shipping revenue, miscellaneous part sales, amortized license fees, reagent 
sales and grant revenue, increased 12% to $5.9 million for the year ended December 31, 2009 compared to $5.3 million for the 
year ended December 31, 2008. This increase is primarily the result of an increase in grant revenue.  

Gross Profit. The gross profit margin percentage (gross profit as a percentage of total revenue) for the technology segment 
remained  flat  at  66%  for  the  years  ended  December 31,  2009  and  2008.  The  increase  in  royalty  revenue,  one  of  our  higher 
margin items, was offset by the decrease in consumable sales, another of our higher margin items. Consumables and royalties 
comprised $46.6 million, or 53%, of technology segment revenue for the year ended December 31, 2009 and $46.6 million, or 
56%,  for  the  year  ended  December 31,  2008.  Gross  profit  for  the  technology  segment  increased  to  $57.6 million  for  the  year 
ended December 31, 2009, as compared to $54.8 million for the year ended December 31, 2008. The increase in gross profit was 
primarily attributable to the overall increase in revenue.  

Operating expenses. Research and development expenses increased to $10.9 million for the year ended December 31, 2009 
from  $10.8 million  for  the  year  ended  December 31,  2008.  The  slight  increase  was  primarily  attributable  to  an  increase  in 
personnel costs associated with the addition of employees offset by a decrease in professional consulting fees. The increase in the 
number of employees has allowed us to enhance our focus on development of our system, consumable and software products and 
the expansion of applications for use on our platforms. As a percentage of revenue, research and development expense was 12% 
in 2009 and 13% in 2008.  

Selling,  general  and  administrative  expenses  increased  to  $38.7 million  for  the  year  ended  December 31,  2009  from 
$34.9 million for the comparable period in 2008. The increase was primarily related to additional personnel costs and the related 
stock  compensation  and  travel  costs  associated  with  the  increase  in  employees  and  contract  employees  of  the  technology 
segment to 119 at December 31, 2009 from 99 at December 31, 2008 and higher legal and professional fees. As a percentage of 
revenue, selling, general and administrative expenses were 44% in 2009 and 42% in 2008.  

46

                                   
   
Income taxes. Income tax expense decreased in 2009 due to the $14.9 million tax benefit from the release of a portion of 

our total valuation allowance on deferred U.S. tax assets.  

Selected financial data for the year ended December 31, 2008 and 2007 of our technology segment is as follows:  

Revenue 
Gross profit 
Gross margin percentage 
Operating expenses 
Net income 

Year Ended December 31,

2008

2007
(dollars in thousands)

Variance  

$
$

$
$

83,567
54,756

66%

45,723
9,405

$
$

$
$

62,436
37,864

61%

38,391
12,330

$
$

$
$

21,131 
16,892 

5% 

7,332 
(2,925)  

Variance  
(%)

34%
45%

N/A

19%
24%

Revenue. Total revenue increased 34% to $83.6 million for the year ended December 31, 2008 from $62.4 million in 2007. 
The increase in revenue was primarily attributable to an increase in consumable, royalty and system revenue as a result of our 
efforts  to  accelerate  instrument  placements,  menu  expansion,  and  increasing  utilization  of  our  partners’  assays  on  our 
technology.  

A  breakdown  of  revenue  in  the  technology  segment  for  the  years  ended  December 31,  2008  and  2007  is  as  follows  (in 

thousands):  

System sales 
Consumable sales 
Royalty revenue 
Service contracts 
Other revenue 

Year Ended December 31,

2008

2007

$

$

26,408   
31,678   
14,897   
5,290   
5,294   
83,567   

$

$

23,320 
19,197
10,213
4,431
5,275 
62,436

The top five customers, by revenue, accounted for 62% of total revenue in 2008 compared to 61% in 2007. In particular, 
two customers accounted for 45% of 2008 total technology segment revenue (24% and 21%, respectively) compared to 42% of 
2007 total technology segment revenue (18% and 24%, respectively). No other customer accounted for more than 10% of total 
technology segment revenue.  

System  and  peripheral  component  sales  increased  13%  to  $26.4 million  for  the  year  ended  December 31,  2008  from 
$23.3 million  for  the  year  ended  December 31,  2007.  System  sales  increased  to  875  systems  for  2008  as  compared  to  838 
systems in the prior year.  

Consumable  sales,  comprised  of  microspheres  and  sheath  fluid,  increased  65%  to  $31.7 million  during  2008  from 
$19.2 million in 2007. This was primarily the result of an increase in bulk purchases due to increased commercial activity by our 
partners. Partners who reported royalty bearing sales accounted for $28.2 million, or 89%, of total consumable sales for the year 
ended  December 31,  2008.  In  addition,  during  2008  we  had  49  bulk  purchases  of  consumables  totaling  approximately 
$26.1 million as compared with 41 bulk purchases totaling approximately $14.3 million in the prior year.  

Royalty  revenue  increased  46%  to  $14.9 million  for  the  year  ended  December 31,  2008  from  $10.2  million  for  the  year 
ended  December 31,  2007.  We  believe  this  was  primarily  the  result  of  our  efforts  to  accelerate  instrument  placements,  menu 
expansion, and increasing utilization of our partner’s assays on our technology. For the year ended December 31, 2008, we had 
35  commercial  partners  submit  royalties  as  compared  with  30  for  the  year  ended  December 31,  2007.  Additionally,  the  30 
partners  from  whom  we  recognized  $10.2 million  in  royalties  in  2007  represented  approximately  $14.6 million  of  the  total 
royalties in 2008, an increase of approximately 43% over their prior year payments. Total royalty bearing sales reported to us by 
our  partners  were  approximately  $238.5 million  for the  year  ended  December 31,  2008  as  compared  to  $167.0 million  for  the 
year ended December 31, 2007.  

47

                                   
   
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
   
  
   
   
 
 
 
 
 
 
 
   
 
 
 
 
 
 
  
   
 
 
 
 
 
 
Service contracts, comprised of extended warranty contracts earned ratably over the term of a contract, increased 19% to 
$5.3 million during 2008 from $4.4 million in 2007. This increase was attributable to additional resources allocated to the sale of 
extended service  agreements  resulting in  increased penetration of the expanded installed base.  At  December 31, 2008, we had 
967 Luminex systems covered under extended service agreements and $2.1 million in deferred revenue related to those contracts. 
At December 31, 2007, we had 799 Luminex systems covered under extended service agreements and $1.8 million in deferred 
revenue related to those contracts.  

Other revenue, comprised of training revenue, shipping revenue, miscellaneous part sales, amortized license fees, reagent 

sales and grant revenue, stayed flat at $5.3 million for the years ended December 31, 2008 and 2007.  

Gross Profit. The gross profit margin percentage (gross profit as a percentage of total revenue) for the technology segment 
increased to 66% for the year ended December 31, 2008 from 61% for the year ended December 31, 2007. Gross profit for the 
technology segment increased to $54.8 million for the year ended December 31, 2008, as compared to $37.9 million for the year 
ended December 31, 2007. The increase in gross profit margin percentage was primarily attributable to changes in revenue mix 
between our higher and lower gross margin items. The increase in gross profit was primarily attributable to the overall increase 
in  revenue  coupled  with the  increase  in  gross margin.  Consumables  and royalties,  two  of our  higher  margin items, comprised 
$46.6 million, or 56%, of technology segment revenue for the year ended December 31, 2008 and $29.4 million, or 47%, for the 
year ended December 31, 2007.  

Operating expenses. Research and development expenses increased to $10.8 million for the year ended December 31, 2008 
from $8.9 million for the year ended December 31, 2007. The increase was primarily attributable to an increase in materials and 
supplies  and  additional  personnel  costs  associated  with  the  addition  of  employees  in the  technology  segment.  The  increase  in 
materials  and  supplies  and  the  number  of  employees  has  allowed  us  to  enhance  our  focus  on  development  of  our  system, 
consumable  and  software  products  and  the  expansion  of  applications  for  use  on  our  platforms.  As  a  percentage  of  revenue, 
research and development expense was 13% in 2008 and 14% in 2007.  

Selling,  general  and  administrative  expenses  increased  to  $34.9 million  for  the  year  ended  December 31,  2008  from 
$29.4 million for the comparable period in 2007. The increase was primarily related to additional personnel costs and the related 
stock  compensation  and  travel  costs  associated  with  the  increase  in  employees  and  contract  employees  of  the  technology 
segment to 99 at December 31, 2008 from 81 at December 31, 2007 and higher legal and professional fees. As a percentage of 
revenue, selling, general and administrative expenses were 42% in 2008 and 47% in 2007.  

Settlement  of  litigation.  We  settled  our  pending  litigation  with  RBM  on  October 15,  2007.  As  part  of  the  settlement, 
Luminex  received  a  cash  payment  of  $12.5 million.  $11.5 million  was  recognized  as  part  of  net  income  in  2007,  while 
$1.0 million was deferred for licensing rights granted to RBM from Luminex.  

48  

                                   
   
Assay Segment  

Selected financial data for the year ended December 31, 2009 and 2008 of our assay segment is as follows:  

Revenue 
Gross profit 
Gross margin percentage 
Operating expenses 
Net loss 

Year Ended December 31,

2009

2008
(dollars in thousands)

Variance  

$
$

$
$

33,254
23,645

71% 

24,368
(3,677)

$
$

$
$

20,880
16,190

78% 

21,870
(6,348)

$
$

$
$

12,374 
7,455 

(6)% 

2,498 
2,671 

Variance
(%)

59%
46%

N/A 
(11)%
42%

A breakdown of revenue in the assay segment for the years ended December 31 is as follows (in thousands):  

System sales 
Consumable sales 
Royalty revenue 
Assay revenue 
Service contracts 
Other revenue 

Year Ended December 31,

2009

2008

$

$

1,415   
64   
—   
31,054   
293   
428   
33,254   

$

$

1,728
46
— 
18,715
73
318
20,880

Revenue. Total revenue increased 59% to $33.3 million for the year ended December 31, 2009 from $20.9 million in 2008. 
The  increase  in  revenue was  primarily  attributable  to a 66%  increase  in  assay  revenue,  driven  primarily  by  increased  sales  of
RVP resulting from the H1N1 influenza. We currently do not anticipate the occurrence of a pandemic influenza to contribute to 
our 2010 results. The top five customers, by revenue, accounted for 81% of total revenue in 2009 compared to 72% in 2008. In 
particular, the top two customers in 2009, one of which was not a top two customer in 2008, accounted for 52% of total revenue 
(31% and 21%, respectively) compared to the top two customers of 2008 which accounted for 48% of total revenue (27% and 
21%, respectively). The majority of our assay segment revenues are generated from the sale of test kits. Historically, over 70% of 
our total assay revenue was derived from our CF product line. In the year ended December 31, 2009, our top two assay segment 
products  were RVP  and  CF.  These two  products  represented approximately  89%  and  83%  of total  assay  revenue in  the  years 
ended December 31, 2009 and 2008, respectively. System sales during the year ended 2009 in the assay segment decreased to 35 
systems  compared  to  40  systems  in  2008.  Other  revenue  includes  contract  research  and  development  fees  and  commercial 
milestone revenue.  

Gross  profit.  The  gross  profit  margin  percentage  (gross  profit  as  a  percentage  of  total  revenue)  for  the  assay  segment 
decreased to 71% for the year ended December 31, 2009 from 78% for the year ended December 31, 2008. Gross profit for the 
assay segment increased to $23.6 million for the year ended December 31, 2009, as compared to $16.2 million for the year ended 
December 31, 2008. The decrease in gross profit margin percentage was primarily attributable to a contractual amendment with a 
partner  resulting  in  a  positive  pricing  adjustment  of  $327,000  in  2008  and  accelerated  amortization  in  2009  of  a  license 
agreement related to the termination of a supply contract associated with our FlexmiR product line. The increase in gross profit 
was primarily attributable to the overall increase in revenue offset by the decrease in gross margin.  

Operating expenses. Research and development expenses increased to $9.9 million for the year ended December 31, 2009 
from $7.8 million for the year ended December 31, 2008. The increase in research and development expenses was primarily due 
to  increased  activity  by  the  assay  segment  related  to  product  development,  additional  personnel  costs  and  the  related  stock 
compensation  costs  associated  with  the  increase  in  research  and  development  employees  and  contract  employees  of  the  assay 
segment to 60 at December 31, 2009 from 45 at December 31, 2008.  

49

                                   
   
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
   
 
  
   
   
 
 
 
 
 
 
 
   
 
 
 
 
 
 
  
   
 
 
 
 
 
 
Selling, general and administrative expenses, including the amortization of acquired intangibles, increased to $14.5 million 
for  the  year  ended  December 31,  2009  from  $14.1 million  for  the  comparable  period  in  2008.  The  slight  increase  in  selling, 
general  and  administrative  expenses  was  primarily  due  to  a  decrease  in  marketing  expenses,  outside  services  and  legal  fees, 
offset by a payment of $780,000 made related to the termination of a supply contract associated with our FlexmiR product line. 
We  launched our next generation FlexmiR in July 2009. This termination is not expected  to affect  FlexmiR  product supply  to 
customers.  

Selected financial data for the year ended December 31, 2008 and 2007 of our assay segment is as follows:  

Revenue 
Gross profit 
Gross margin percentage 
Operating expenses 
Net loss 

2008

Year Ended December 31,

Variance  
$

2007
(dollars in thousands)

Variance
(%)

$
$

$
$

20,880
16,190

78%

21,870 
(6,348)

$
$

$
$

12,574
8,230

65%

25,121 
(15,041)

$
$

$
$

8,306 
7,960 

13% 
(3,251)  
8,693 

66%
97%

N/A
(13)%
58%

Revenue. Revenues were derived from LBG for the twelve months ended December 31, 2008 and 2007 and also from LMD 

from March 1, 2007 through December 31, 2008.  

A breakdown of revenue in the assay segment for the years ended December 31 is as follows (in thousands):  

System sales 
Consumable sales 
Royalty revenue 
Service contracts 
Assay revenue 
Other revenue 

Year Ended December 31,

2008

2007

$

$

1,728   
46   
—   
73   
18,715   
318   
20,880   

$

$

1,108
2
31
—
11,323
110
12,574 

The top five customers, by revenue, accounted for 72% of total revenue in 2008 compared to 64% in 2007. In particular, the 
top two customers in 2008 accounted for 48% of total revenue (27% and 21%, respectively) compared to the top two customers 
of 2007 which accounted for 46% of total revenue (33% and 13%, respectively. In the year ended December 31, 2008, as a result 
of the launch of our RVP product in January, 2008, our top two assay segment products were CF and RVP. These two products 
represented over 83% of total assay revenue in the year ended December 31, 2008. System sales during the year ended 2008 in 
the  assay  segment  increased  to  40  systems  compared  to  24  systems  in  2007.  Other  revenue  includes  contract  research  and 
development fees and commercial milestone revenue.  

Gross  profit.  The  gross  profit  margin  percentage  (gross  profit  as  a  percentage  of  total  revenue)  for  the  assay  segment 
increased to 78% for the year ended December 31, 2008 from 65% for the year ended December 31, 2007. Gross profit for the 
assay segment increased to $16.2 million for the year ended December 31, 2008, as compared to $8.2 million for the year ended 
December 31,  2007.  The  increase  in  gross  profit  margin  percentage  was  primarily  attributable  to  increased  utilization  and 
capacity at LMD, increased sales of higher gross margin assays, and changes in revenue mix between our higher and lower gross 
margin items. The increase in gross profit was primarily attributable to the overall increase in revenue coupled with the increase 
in gross margin.  

50

                                   
   
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
   
  
   
   
 
 
 
 
 
   
 
   
 
   
  
 
   
 
 
 
 
 
 
Operating expenses. Research and development expenses increased to $7.8 million for the year ended December 31, 2008 
from $6.4 million for the year ended December 31, 2007. The increase in research and development expenses was primarily due 
to  incorporation  of  the  results  of  LMD  for  the  full  twelve  months  in  2008  compared  to  the  inclusion  of  only  ten  months  of 
operating results of LMD in the year ended December 31, 2007, as the acquisition was consummated on March 1, 2007, and to a 
lesser extent, to increased activity by the assay segment related to product development.  

Selling,  general  and  administrative  expenses  increased  to  $12.1 million  for  the  year  ended  December 31,  2008  from 
$9.6 million  for  the  comparable  period  in  2007,  excluding  the  non-recurring  $7.4 million  write-off  of  in-process  research  and 
development related to the acquisition of LMD, for the nine months ended September 30, 2007. The overall increase in selling, 
general, and administrative expenses is primarily due to the addition of costs associated with LMD. As previously discussed, the 
expenses  for  the  year  ended  December 31,  2007  include  expenses  related  to  LBG  for  the  entire  twelve  months  and  expenses 
related  to  LMD  for  ten  months  only.  The  overall  increase  in  selling,  general  and  administrative  expenses  was  primarily 
attributable to the addition of LMD and to a lesser extent increased activity by the LBG.  

Gain on settlement of liability. $2.3 million was recognized in the year ended December 31, 2007 related to the settlement 

of a liability related to the renegotiation of a contract acquired as part of the acquisition of Tm Bioscience.  

Liquidity and Capital Resources  

Cash and cash equivalents 
Short-term investments 
Long-term investments 

December 31,    December 31,

2009

2008

(in thousands)

90,843   
8,511   
20,228   
119,582   

$

$

81,619
40,501
2,000
124,120

$

$

At December 31, 2009, we held cash, cash equivalents and short-term and long-term investments of $119.6 million and had 
working  capital  of  $122.4 million.  At  December 31,  2008,  we  held  cash,  cash  equivalents  and  short-term  and  long-term 
investments of $124.1 million and had working capital of $131.5 million. Cash, cash equivalents and investments have decreased 
by approximately $4.5 million during the year ended December 31, 2009 due primarily to capital expenditures and an increase in 
our accounts receivable.  

We  have funded  our  operations  to  date  primarily  through  the  issuance of  equity securities (in conjunction  with an initial 
public  offering  in  2000,  subsequent  option  exercises,  and  our  follow-on  public  offering  in  2008)  and  cash  generated  from 
operations.  Our  cash  reserves  are  held  directly  or  indirectly  in  a  variety  of  short-term,  interest-bearing  instruments,  including
obligations of the United States government or agencies thereof and United States corporate debt securities. We do not have any 
investments in asset-backed commercial paper, auction rate securities, or mortgage backed or sub-prime style investments.  

Cash provided by operations was $5.8 million for the year ended December 31, 2009. Significant items affecting operating 
cash flows for the period were our net income of $17.7 million and adjustments for depreciation and amortization of $8.3 million 
and stock compensation of $8.2 million, offset by the $15.5 million increase in our deferred income taxes due to our release of 
the valuation allowance, an increase in accounts receivable of $10.8 and an increase in inventory of $5.9 million.  

51  

                                   
   
 
   
   
 
 
 
   
 
 
 
 
   
 
 
 
 
 
 
  
   
 
 
 
 
 
 
Cash provided by investing activities was $3.3 million for the year ended December 31, 2009 as compared with cash used 
in investing of $41.7 million for the year ended December 31, 2008. In 2009, our purchases of securities decreased as we decided 
to  hold  maturing  short-term  investments in  cash and cash  equivalents.  Capital expenditures  for property,  plant  and  equipment 
increased to $10.4 million from $4.4 million in 2008. The increase is primarily related to leasehold improvements for additional 
space leased in the U.S. and the Netherlands, acquisitions of FLEXMAP 3D systems for internal use, leasehold improvements 
for  our  new  office  in  the  People’s Republic  of  China,  and purchases of  equipment for  our  business  continuity  site. Currently, 
exclusive of changes in investments, we expect cash used in investing activities to be primarily for purchases of property, plant 
and equipment.  

Cash  provided  by  financing  activities  was  $0.6 million  for  the  year  ended  December 31,  2009  as  compared  with  cash 
provided by financing activities of $81.7 million for the year ended December 31, 2008 due to our follow-on public offering in 
June of 2008 of $74.7 million and a decrease in the proceeds from issuance of common stock due to exercises of stock options 
and warrants of $0.6 million in 2009 compared to $7.1 million in 2008.  

Our  future  capital  requirements  will  depend  on  a  number  of  factors,  including  our  success  in  developing  and  expanding 
markets  for  our  products,  payments  under  possible  future  strategic  arrangements,  continued  progress  of  our  research  and 
development  of  potential  products,  the  timing  and  outcome  of  regulatory  approvals,  the  need  to  acquire  licenses  to  new 
technology, costs associated with strategic acquisitions including integration costs and assumed liabilities, litigation expense, the 
status  of  competitive  products  and  potential  cost  associated  with  both  protecting  and  defending  our  intellectual  property. 
Additionally,  actions  taken  as  a  result  of  the  ongoing  internal  evaluation  of  our  business  could  result  in  expenditures  not 
currently contemplated in our estimates for 2010. We believe, however, that our existing cash and cash equivalents are sufficient 
to fund our operating expenses, capital equipment requirements and other expected liquidity requirements for the coming twelve 
months. Factors that could affect our capital requirements, in addition to those listed above include: (i) continued collections of 
accounts receivable consistent with our historical experience, (ii) our ability to manage our inventory levels consistent with past 
practices, and (iii) signing of partnership agreements which include significant up front license fees. See also the “Safe Harbor 
Cautionary Statement” and Item 1A “Risk Factors” above.  

To the extent our capital resources are insufficient to meet future capital requirements we will have to raise additional funds 
to continue  the  development and deployment of our technologies. There can  be no assurance that debt or equity funds will be 
available  on  favorable  terms,  if  at  all,  particularly  given  the  current  state  of  the  capital  markets.  To  the  extent  that  additional 
capital is raised through the sale of equity or convertible debt securities, the issuance of those securities could result in dilution to 
our  stockholders.  Moreover,  incurring  debt  financing  could  result  in  a  substantial  portion  of  our  operating  cash  flow  being 
dedicated  to  the  payment  of  principal  and  interest  on  such  indebtedness,  could  render  us  more  vulnerable  to  competitive 
pressures and economic downturns and could impose restrictions on our operations. If adequate funds are not available, we may 
be required to curtail operations significantly or to obtain funds through entering into agreements on unattractive terms.  

52  

                                   
   
Contractual Obligations  

As of December 31, 2009, we had approximately $11.7 million in non-cancelable obligations for the next 12 months. These 
obligations are included in our estimated cash usage during 2009. The following table reflects our total current non-cancelable 
obligations by period as of December 31, 2009 (in thousands):  

Payments Due By Period

Contractual Obligations
Non-cancelable rental obligations 
Non-cancelable purchase obligations (1) 
Long-term debt obligations (2) 
Capital lease obligations 

Total
$ 11,421
12,662
5,430
20

Less Than
1 Year

$

2,446
8,330
868
20

1-3 Years
4,656
$
1,552
2,090

—  

    More Than

3-5 Years   
3,801   
$
1,082   
2,472   
—   

$

5 Years

518
1,698
—
—

Total (3) 

$ 29,533

$

11,664

$

8,298

$

7,355   

$

2,216

(1)   Purchase  obligations  include  contractual  arrangements  in  the  form  of  purchase  orders  primarily  as  a  result  of  normal

inventory purchases or minimum payments due resulting when minimum purchase commitments are not met. 

(2)   On December 12, 2003, LMD entered into an agreement with the Ministry of Industry of the Government of Canada under
which the Government agreed to invest up to Canadian (Cdn) $7.3 million relating to the development of several genetic
tests. This agreement was amended in March 2009. Funds were advanced from Technology Partnerships Canada (TPC), a
special  operating  program.  The  actual  payments  we  received  were  predicated  on  eligible  expenditures  made  during  the
project period which ended July 31, 2008. LMD has received Cdn $4.9 million from TPC which is expected to be repaid
along with approximately Cdn $1.6 million of imputed interest for a total of approximately Cdn $6.5 million. 

  LMD has agreed to repay the TPC funding through a royalty on revenues. Royalty payments commenced in 2007 at a rate
of 1% of total revenue and at a rate of 2.5% for 2008 and thereafter. Aggregate royalty repayment will continue until total
advances plus imputed interest has been repaid or until December 31, 2016, whichever is earlier. The repayment obligation
expires  on  December 31,  2016  and  any  unpaid  balance  will  be  cancelled  and  forgiven  on  that  date.  Should  the  term  of
repayment be shorter than expected due to higher than expected assay revenue, the effective interest rate would increase as
repayment  is  accelerated.  Repayments  denominated  in  U.S.  Dollars  are  currently  projected  to  be  as  shown  in  the  table
above, but actual future sales generating a repayment obligation will vary from this projection and are subject to the risks
and  uncertainties  described  elsewhere  in  this  report,  including  under  “Risk  Factors”  and  “Safe  Harbor  Cautionary 
Statement.” Furthermore, payment reflected in U.S. Dollars is subject to adjustment based upon applicable exchange rates
as of the reporting date. The amount due within one year, as shown in the table above, is our estimated repayment amount
based on the current projected sales for the full year 2009. 

(3)   Due to the uncertainty with respect to the timing of future cash flows associated with Luminex’s unrecognized tax benefits 
at December 31, 2009, Luminex is unable to make reasonably reliable estimates of the timing of cash settlement with the
respective taxing authority. Therefore, $0.8 million of unrecognized tax benefits have been excluded from the contractual
obligations table above. See Note 10 to the Consolidated Financial Statements for a discussion on income taxes. 

Inflation  

We do not believe that inflation has had a direct adverse effect on our operations to date. However, a substantial increase in 
product and manufacturing costs and personnel related expenses could have an adverse impact on our results of operations in the 
event these expenses increase at a faster pace than we can increase our system, consumable and royalty rates.  

53

                                   
   
 
 
   
   
   
   
 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
   
   
   
   
   
   
   
   
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Recently Adopted Accounting Standards  

In  June 2009,  the  FASB  issued  ASC  Update  No. 2009-01  (ASU  No. 2009-01),  “Topic  105  —  Generally  Accepted 
Accounting Principles,” which amends the ASC for the issuance of Statement of Financial Accounting Standards No. 168 (SFAS 
No. 168),  “The  FASB  Accounting  Standards  Codification  and  the  Hierarchy  of  Generally  Accepted  Accounting  Principles.”
ASU  No. 2009-01  includes  SFAS  No. 168  in  its  entirety  and  establishes  the  ASC  as  the  source  of  authoritative  accounting 
principles  recognized  by  FASB  for  all  nongovernmental  entities  in  the  preparation  of  financial  statements  in  accordance  with 
GAAP.  For  SEC  registrants,  rules  and  interpretive  releases  of  the  SEC  under  federal  securities  laws  are  also  considered 
authoritative sources of GAAP. The guidance is effective for financial statements issued for interim and annual periods ending 
after September 15, 2009. We adopted the FASB ASC for fiscal year ended December 31, 2009. The adoption had no impact on 
our financial statements. All references to authoritative guidance have been updated to cite relevant ASC Topics, as applicable.  

Recent Accounting Pronouncements  

The  FASB  recently  amended  its  guidance  on  the  information  that  a  reporting  entity  must  provide  in  its  financial  reports 
about a transfer of financial assets; the effects of a transfer on its financial position, financial performance, and cash flows; and a 
transferor’s continuing involvement in transferred financial assets. Specifically, among other aspects, the new guidance amends 
previous  guidance  related  to  the  concept  of  a  qualifying  special-purpose  entity,  variable  interest  entities  that  are  qualifying 
special-purpose  entities  and  the  financial-components  approach.  The  new  guidance  is  effective  for  transfer  of  financial  assets 
occurring on or after January 1, 2010. We have not determined the effect that the adoption of the new guidance will have on its 
financial position or results of operations but the effect will generally be limited to future transactions. Historically, we have not 
had any material transfers of financial assets. Additionally, the FASB recently amended its guidance surrounding a company’s 
analysis to determine whether its variable interest or interests give it a controlling financial interest in a variable interest entity. 
The  primary  beneficiary  of  a  variable  interest  entity  is  the  enterprise  that  has  both  (1) the  power  to  direct  the  activities  of  a 
variable interest entity that most significantly impact the entity’s economic performance and (2) the obligation to absorb losses of 
the entity that could potentially be significant to the variable interest entity or the right to receive benefits from the entity that 
could potentially be significant to the variable interest entity. This new guidance also requires ongoing reassessments of whether 
an enterprise is the primary beneficiary of a variable interest entity. The guidance is effective for all variable interest entities and 
relationships with variable interest entities existing as of January 1, 2010. We do not expect the adoption of this standard to have 
an impact on our financial position or results of operations.  

In October 2009, the FASB updated its revenue recognition guidance, amending the criteria for separating consideration in 
multiple-deliverable  arrangements.  The  amendments  establish  a  selling  price  hierarchy  for  determining  the  selling  price  of  a 
deliverable. The selling price used for  each deliverable will be based on vendor-specific objective evidence if  available, third-
party  evidence  if  vendor-specific  objective  evidence  is  not  available,  or  estimated  selling  price  if  neither  vendor-specific 
objective evidence  nor third-party evidence is available. The amendments will eliminate the residual method of allocation  and 
require  that  arrangement  consideration  be  allocated  at  the  inception  of  the  arrangement  to  all  deliverables  using  the  relative 
selling  price  method.  The  relative  selling  price  method  allocates  any  discount  in  the  arrangement  proportionally  to  each 
deliverable on the basis of each deliverable’s selling price. This update will be effective prospectively for revenue arrangements 
entered  into  or  materially  modified  in  fiscal  years  beginning  on  or  after  June 15,  2010.  Early  adoption  is  permitted.  We  are 
currently  evaluating  the  requirements  of  this  update  and  have  not  yet  determined  the  impact  on  our  consolidated  financial 
statements.  

In October 2009, the FASB updated its software guidance, changing the accounting model for revenue arrangements that 
include  both  tangible  products  and  software  elements.  Tangible  products  containing  software  components  and  non-software 
components that function together to deliver the tangible product’s essential functionality are no longer within the scope of the 
software  revenue  guidance.  In  addition,  the  amendments  require  that  hardware  components  of  a  tangible  product  containing 
software  components  always  be  excluded  from the  software  revenue guidance.  This update  will be effective prospectively for 
revenue arrangements entered into or materially modified in fiscal years beginning on or after June 15, 2010. Early adoption is 
permitted.  We  are  currently  evaluating  the  requirements  of  this  update  and  have  not  yet  determined  the  impact  on  our 
consolidated financial statements.  

54

                                   
   
In January 2010, the FASB updated it guidance related to fair value measurements and disclosures. This guidance requires 
some  new  disclosures  and  clarifies  some  existing  disclosure  requirements  about  fair  value  measurement  in  order  to  improve 
these disclosures and, thus, increase the transparency in financial reporting. Specifically, guidance will require a reporting entity 
to disclose separately the amounts of significant transfers in and out of Level 1 and Level 2 fair value measurements and describe 
the  reasons  for  the  transfers  and  present  separately  information  about  purchases,  sales,  issuances,  and  settlements  in  the 
reconciliation for fair value measurements using significant unobservable inputs. In addition, the FASB clarified the disclosure 
requirements related to the use of  judgment in determining the appropriate classes  of  assets and liabilities when reporting fair 
value measurement for each class and about the valuation techniques and inputs used to measure fair value for both recurring and 
nonrecurring  fair  value  measurements.  The  update  is  effective  for  interim  and  annual  reporting  periods  beginning  after 
December 15, 2009, except for the disclosures about purchases, sales, issuances, and settlements in the roll forward of activity in 
Level  3  fair  value  measurements.  Those  disclosures  are  effective  for  fiscal  years  beginning  after  December 15,  2010,  and  for 
interim  periods  within  those  fiscal  years.  Early  application  is  permitted.  We  are  currently  evaluating  the  requirements  of  this 
update and have not yet determined the impact on our consolidated financial statements.  

ITEM 7A. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK  

Interest Rate Risk.  Our  interest  income is sensitive  to  changes in the  general  level of  domestic interest  rates, particularly 
since our investments are in short-term and long-term instruments available-for-sale. A 50 basis point fluctuation from average 
investment  returns  at  December 31,  2009  would  yield  an  approximate  1%  variance  in  overall  investment  return.  Due  to  our 
intention to hold our investments to maturity, we have concluded that there is no material market risk exposure.  

Foreign Currency Risk. As of December 31, 2009, as a result of our foreign operations, we have costs, assets and liabilities 
that are denominated in foreign currencies, primarily Canadian dollars and to a lesser extent the Euro, Renminbi, and Yen. For 
example, some fixed asset purchases, certain expenses, and the TPC debt of our Canadian subsidiary, LMD, are denominated in 
Canadian  dollars  while  sales  of  products  are  primarily  denominated  in  U.S.  dollars.  All  transactions  in  our  Netherlands  and 
Japanese subsidiaries are denominated in Euros and Yen, respectively. All transactions, with the exception of our initial capital 
investment,  in  our  Chinese  subsidiary  are  denominated  in  Renminbi.  As  a  consequence,  movements  in  exchange  rates  could 
cause our foreign currency denominated expenses to fluctuate as a percentage of net revenue, affecting our profitability and cash 
flows.  A  significant  majority  of  our  revenues  are  denominated  in  U.S.  dollars.  The  impact  of  foreign  exchange  on  foreign 
denominated  balances  will  vary  in  relation  to  changes  between  the  U.S.  and  Canadian  Dollar,  Euro,  Yen,  and  Renminbi 
exchange  rates.  A  10%  change  in  these  exchange  rates  in  relation  to  the  U.S.  dollar  would  result  in  an  immaterial  foreign 
exchange impact. As a result of our efforts to expand globally, in the future we will be exposed to additional foreign currency 
risk in multiple currencies; however, at this time, our exposure to foreign currency fluctuations is not material.  

In  addition,  the indirect effect  of  fluctuations  in  interest  rates  and foreign currency  exchange  rates could  have  a  material 
adverse  effect  on  our  business  financial  condition  and  results  of  operations.  For  example,  currency  exchange  rate fluctuations 
could  affect  international  demand  for  our  products.  In  addition,  interest  rates  fluctuations  could  affect  our  customers’  buying 
patterns. Furthermore, interest rate and currency exchange rate fluctuations may broadly influence the United States and foreign 
economies resulting in  a material adverse effect on our business, financial condition  and results of operations. As  a result, we 
cannot give any assurance as to the effect that future changes in foreign currency rates will have on our consolidated financial 
position,  results  of  operations  or  cash  flows.  Our  aggregate  foreign  currency  transaction  loss  of  $214,000  was  included  in 
determining our consolidated results for the year ended December 31, 2009.  

55

                                   
   
ITEM 8.   FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

Index to Consolidated Financial Statements  

Report of Independent Registered Public Accounting Firm

Report of Independent Registered Public Accounting Firm

Consolidated Balance Sheets 

Consolidated Statements of Operations 

Consolidated Statements of Cash Flows

Consolidated Statements of Changes in Stockholders’ Equity

Notes to Consolidated Financial Statements 

56

PAGE

57

58

59

60 

61

62

63

                                   
   
 
 
   
 
 
  
 
   
 
 
 
  
 
   
 
 
  
 
   
 
 
  
 
   
 
 
  
 
   
 
 
  
 
   
 
 
  
 
   
 
 
  
 
   
 
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM  

The Board of Directors and Shareholders of  
Luminex Corporation  

We  have  audited  Luminex  Corporation’s  internal  control  over  financial  reporting  as  of  December 31,  2009,  based  on  criteria 
established in Internal Control—Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway 
Commission (the COSO criteria). Luminex Corporation’s management is responsible for maintaining effective internal control 
over financial reporting,  and  for  its  assessment of  the  effectiveness  of internal  control over  financial reporting included in the 
accompanying Management’s Report on Internal Control over Financial Reporting. Our responsibility is to express an opinion 
on the company’s internal control over financial reporting based on our audit.  

We conducted our audit in accordance with the standards of the Public Company Accounting Oversight Board (United States). 
Those  standards  require  that  we  plan  and  perform  the  audit  to  obtain  reasonable  assurance  about  whether  effective  internal 
control over financial reporting was maintained in all material respects. Our audit included obtaining an understanding of internal 
control  over  financial  reporting,  assessing  the  risk  that  a  material  weakness  exists,  testing  and  evaluating  the  design  and 
operating effectiveness of  internal control  based on  the  assessed  risk, and  performing  such  other  procedures as we  considered 
necessary in the circumstances. We believe that our audit provides a reasonable basis for our opinion.  

A  company’s  internal  control  over  financial  reporting  is  a  process  designed  to  provide  reasonable  assurance  regarding  the 
reliability  of  financial  reporting  and the preparation of financial statements for external purposes  in accordance with generally 
accepted accounting principles. A company’s internal control over financial reporting includes those policies and procedures that 
(1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions 
of the assets of the company; (2) provide reasonable assurance that transactions are recorded as necessary to permit preparation 
of  financial  statements  in  accordance  with  generally  accepted  accounting  principles,  and  that  receipts  and  expenditures  of  the 
company are being made only in accordance with authorizations of management and directors of the company; and (3) provide 
reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company’s 
assets that could have a material effect on the financial statements.  

Because  of  its  inherent  limitations,  internal  control  over  financial  reporting  may  not  prevent  or  detect  misstatements.  Also, 
projections  of  any  evaluation  of  effectiveness  to  future  periods  are  subject  to  the  risk  that  controls  may  become  inadequate 
because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.  

In our opinion, Luminex Corporation maintained, in all material respects, effective internal control over financial reporting as of 
December 31, 2009, based on the COSO criteria.  

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States), the 
consolidated balance sheets of Luminex Corporation as of December 31, 2009 and 2008, and the related consolidated statements 
of  operations,  stockholders’  equity,  and  cash  flows  for  each  of  the  three  years  in  the  period  ended  December 31,  2009  of 
Luminex Corporation and our report dated February 25, 2010 expressed an unqualified opinion thereon.  

Austin, Texas 
February 25, 2010  

/s/ Ernst & Young LLP  

57

  
   
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM  

The Board of Directors and Shareholders of 
Luminex Corporation  

We  have  audited  the  accompanying  consolidated  balance  sheets  of  Luminex  Corporation  (the  Company)  as  of  December 31, 
2009 and 2008, and the related consolidated statements of operations, stockholders’ equity and cash flows for each of the three 
years in the period ended December 31, 2009. These financial statements are the responsibility of the Company’s management. 
Our responsibility is to express an opinion on these consolidated financial statements based on our audits.  

We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States). 
Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements 
are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures 
in  the financial  statements.  An  audit  also  includes assessing the  accounting  principles  used  and  significant  estimates made by 
management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable 
basis for our opinion.  

In  our  opinion, the  consolidated  financial  statements referred  to  above  present  fairly,  in  all  material  respects, the consolidated 
financial position of Luminex Corporation at December 31, 2009 and 2008 and the consolidated results of its operations and its 
cash  flows  for  each  of  the  three  years  in  the  period  ended  December 31,  2009,  in  conformity  with  U.S.  generally  accepted 
accounting principles.  

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States), the 
Company’s internal control over financial reporting as of December 31, 2009, based on criteria established in Internal Control—
Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission, and our report dated 
February 25, 2010 expressed an unqualified opinion thereon.  

Austin, Texas 
February 25, 2010  

/s/ Ernst & Young LLP  

58

                                   
   
LUMINEX CORPORATION  
CONSOLIDATED BALANCE SHEETS 
(In thousands, except share and per share amounts)  

Current assets: 

Cash and cash equivalents 
Short-term investments 
Accounts receivable, (net of allowance for doubtful accounts of $523 and $272 at 

December 31, 2009 and 2008, respectively) 

ASSETS

Inventories, net  
Deferred income taxes 
Prepaids and other 

Total current assets 

Property and equipment, net 
Intangible assets, net 
Deferred income taxes 
Long-term investments 
Goodwill 
Other 

Total assets 

Current liabilities: 

Accounts payable 
Accrued liabilities 
Deferred revenue 
Current Portion of long term debt 

Total current liabilities 

Long-term debt 
Deferred revenue 
Other 

Total liabilities 

Stockholders’ equity: 

LIABILITIES AND STOCKHOLDERS’ EQUITY

Common stock, $.001 par value, 200,000,000 shares authorized; issued and outstanding: 

40,736,340 shares in 2009; 40,334,082 shares in 2008

Preferred stock, $.001 par value, 5,000,000 shares authorized; no shares issued and 

outstanding 

Additional paid-in capital 
Accumulated other comprehensive loss (gain) 
Accumulated deficit 

Total stockholders’ equity 

December 31,

2009

2008

$

90,843   
8,511   

$

81,619
40,501

22,108   
17,524   
1,040   
2,130   

11,024
11,589
2
1,658 

142,156   

146,393

17,255   
12,938   
14,732   
20,228   
39,617   
1,087   

12,567 
14,901
274
2,000
39,617
1,539

$

248,013   

$

217,291

$

$

8,430   
7,493   
2,967   
868   

4,580
6,930
2,671
445 

19,758   

14,626

3,591   
4,614   
1,312   

2,914 
4,960
251

29,275   

22,751

41   

40

—   
285,648   
28   
(66,979)  

—
279,255
(47)
(84,708)

218,738   

194,540

Total liabilities and stockholders’ equity

$

248,013   

$

217,291

See the acompanying notes which are an integral part of these Consolidated Financial Statements.  

59

                                   
   
 
 
   
   
   
 
 
 
   
  
 
   
   
 
   
   
   
 
 
 
 
 
 
 
 
   
 
 
 
 
 
  
 
   
   
 
  
 
   
   
 
 
 
 
 
 
 
 
   
 
 
 
 
 
  
 
   
   
   
 
 
 
 
 
  
 
   
   
 
   
   
 
 
 
 
 
   
 
 
 
 
 
  
 
   
   
 
  
 
   
   
 
 
 
 
 
   
 
 
 
 
 
  
 
   
   
 
   
 
 
 
 
 
  
 
   
   
 
   
   
 
 
 
 
 
   
 
 
 
   
  
 
   
   
 
   
 
 
 
 
 
  
 
   
   
   
 
 
 
 
 
  
 
   
   
LUMINEX CORPORATION  
CONSOLIDATED STATEMENTS OF OPERATIONS 
(In thousands, except per share amounts)  

Revenue 

Cost of revenue 

Gross profit 

Operating expenses: 

Research and development 

Selling, general and administrative

In-process research and development 

Gain on settlement of liability 

Total operating expenses 

Income (loss) from operations 

Interest expense from long-term debt

Other income, net 

Settlement of litigation 

Income (loss) before income taxes 

Income taxes 

Net income (loss) 

Net income (loss) per share, basic 

Shares used in computing net income (loss) per share, basic

Net income (loss) per share, diluted 

Shares used in computing net income (loss) per share, diluted

Year Ended December 31,
2008

2007

2009

$

120,643

$

104,447   

$

75,010

39,349

81,294

20,752

53,143

—   

—

73,895

7,399

(481)

719

33,501   

28,916

70,946   

46,094

18,628   

48,965   

—   

—   

15,383

40,729

7,400 

(2,345)

67,593   

61,167

3,353   

(15,073)

(592)  

1,144   

(513)

1,665

(4,350)

—   

11,500

3,287

14,442

17,729

0.44

40,562

0.43

41,633

3,905   

(2,421)

(848)  

(290)

3,057   

0.08   

$

$

(2,711)

(0.08)

37,868   

34,361

0.08   

$

(0.08)

39,700   

34,361

$

$

$

$

$

$

See the accompanying notes which are an integral part of these Consolidated Financial Statements.  

60

                                   
   
 
 
   
   
   
   
   
 
 
 
   
  
 
   
   
  
 
   
   
   
   
   
 
 
   
 
 
 
 
 
 
 
 
  
 
   
   
 
  
 
   
   
   
   
   
 
 
   
   
  
 
   
   
 
  
 
   
   
 
  
 
   
   
 
 
 
 
  
 
   
   
 
   
 
 
 
 
 
 
 
 
  
 
   
   
 
   
 
 
 
 
 
 
 
 
  
 
   
   
 
  
 
   
   
 
  
 
   
   
   
   
   
 
 
  
 
   
   
 
   
 
   
 
 
 
   
  
 
   
   
   
   
   
 
 
   
 
 
 
 
 
 
 
 
  
 
   
   
 
   
 
   
 
 
 
   
  
 
   
   
   
 
 
 
 
 
 
 
 
  
 
   
   
   
 
 
 
 
 
 
 
 
  
 
   
   
 
  
 
   
   
   
 
 
 
 
 
 
 
 
  
 
   
   
 
LUMINEX CORPORATION  
CONSOLIDATED STATEMENTS OF CASH FLOWS 
(In thousands)  

CASH FLOWS FROM OPERATING ACTIVITIES: 
Net income (loss) 

Adjustments to reconcile net income (loss) to net cash provided by 

operating activities: 
Depreciation and amortization expense 
In-process research and development expense 
Gain on settlement of liability 
Amortization of deferred stock, restricted stock and stock 

compensation expense 
Deferred income tax benefit 
Loss on disposal of assets 
Other 

Changes in operating assets and liabilities: 

Accounts receivable, net 
Inventories, net 
Other assets 
Accounts payable 
Accrued liabilities 
Deferred revenue 

Net cash provided by operating activities

CASH FLOWS FROM INVESTING ACTIVITIES: 

Purchases of available-for-sale securities 
Maturities of available-for-sale securities 
Purchases of held-to-maturity securities 
Maturities of held-to-maturity securities 
Purchase of property and equipment
Acquisition of business, net of cash acquired 
Acquisition activity 
Proceeds from sale of assets 
Acquired intangible assets 
Acquired technology rights 

Net cash provided by (used in) investing activities 

CASH FLOWS FROM FINANCING ACTIVITIES: 

Proceeds from debt 
Payments on debt 
Proceeds from secondary offering, net of offering costs
Proceeds from issuance of common stock 
Other 

Net cash provided by (used in) financing activities 
Effect of foreign currency exchange rate on cash 
Change in cash and cash equivalents 
Cash and cash equivalents, beginning of year 
Cash and cash equivalents, end of year

Interest and penalties paid 

SUPPLEMENTAL DISCLOSURE OF NON-CASH EFFECT OF 

ACQUISITIONS: 
Purchase price 
Common stock issued 
Conversion of Tm options and warrants 
Forgiveness of receivable from acquired company 
Write-off of acquired technology rights 
Cash acquired 
Acquisition, net of cash acquired 

Year Ended December 31,
2008

2007

2009

$

17,729

$

3,057   

$

(2,711)

8,329
—
—

8,160
(15,496)  

25
1,665

(10,827)
(5,935)
(699)
3,672   
(765)
(55)
5,803

(62,764)
33,968
—

42,501   
(10,369)
—
—
—
—
(29)
3,307

453
(440)
—
567
—
580
(466)
9,224   
81,619
90,843

456

—
—
—
—
—
—
—

$

$

7,001   
—   
—   

7,251   
(105)  
8   
(415)  

694   
(5,081)  
(837)  
1,760   
(312)  
830   
13,851   

—   
—   
(55,868)  
20,310   
(4,449)  
—   
(481)  
19   
—   
(1,216)  
(41,685)  

—   
(134)  
74,722   
7,075   
—   
81,663   
557   
54,386   
27,233   
81,619   

160   

—   
—   
—   
—   
—   
—   
—   

$

$

$

$

5,063
7,400
(2,345)

6,593
(128)
88
268

(3,255)
(129)
1,147
(2,958)
(715)
75
8,393

—
—
(6,325)
17,717 
(6,685)
(2,686)

30
(10)
(265)
1,776

—
(12,349)
—
1,868
13
(10,468)
118
(181)
27,414
27,233

1,360

(49,401)
41,754
2,315
1,233
473
940
(2,686)

$

$

See the accompanying notes which are an integral part of these Consolidated Financial Statements.  

61

                                   
   
 
 
   
   
   
   
   
 
 
 
   
 
   
   
 
   
   
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
  
 
   
   
 
   
   
 
 
 
 
 
 
 
 
 
   
 
 
 
   
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
  
 
   
   
   
   
   
 
 
   
   
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
  
 
   
   
  
 
   
   
 
   
   
   
   
   
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
LUMINEX CORPORATION  
CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS’ EQUITY 
(In thousands, except per share data)  

Common Stock

  Number of      
Shares

   Amount

Additional
Paid-In
Capital

Accumulated
Other

Total

Comprehensive Accumulated   Stockholders’
Deficit
Income/(Loss)

Equity

Balance at December 31, 2006 
Exercise of stock options 
Issuances of restricted stock, 
net of shares withheld for 
taxes 

Shares Exchanged in Tm 

31,678,608   $
331,754    

32 $ 139,116
1,868
—

$

178,815    

—

(425)

Acquisition 

  3,202,034    

3    

41,751  

—    
—      
—    

—

—

2,315
6,593
—

65
—

—

—  

—

—

$

(85,054)  $

—  

—  

—  

(2,711) 

54,159
1,868

(425)

41,754 

2,315
6,593
(2,711)

Value of Tm options and 

warrants traded 
Stock compensation 
Net income 
Foreign currency translation 

adjustment 

Balance at December 31, 2007 
Exercise of stock options 
Issuances of restricted stock, 
net of shares withheld for 
taxes 

Stock compensation 
Net income 
Secondary public offering, net 

of offering costs 

Tax benefits associated with 

options 

Foreign currency translation 

adjustment 

Balance at December 31, 2008 
Exercise of stock options 
Issuances of restricted stock, 
net of shares withheld for 
taxes 

Stock compensation 
Net income 
Tax benefits associated with 

options 

Foreign currency translation 

adjustment 

Other 

Balance at December 31, 2009 

—    
35,391,211   $
644,057    

—
—
35 $ 191,218
7,075

1

$

(73)

(8) $
—

—  

(87,765)  $

—  

(73)
103,480
7,076

273,814    

—    

—      
—    

4,025,000    

—      

—

4

(1,281) 
7,251
—

74,718

274

—  

—

—  

3,057  

(1,281)
7,251
3,057

74,722

274

—    
40,334,082   $
71,602    

—
—
40 $ 279,255
566

1

$

(39)
(47) $
—

—  

(84,708)  $

—  

(39)
194,540
567

330,656    

—      
—    

—      

—

—

(2,371)
8,160
—

38

—    
—    
40,736,340   $

—  
—    
—
—
41 $ 285,648

$

—

—

12  
63
28

—  

17,729  

—  

$

(66,979)  $

(2,371)
8,160
17,729

38

12 
63
218,738

See the accompanying notes which are an integral part of these Consolidated Financial Statements.  

62

                                   
   
 
 
  
      
      
  
 
 
  
   
  
 
 
 
 
 
      
 
  
 
 
 
  
 
 
 
  
  
 
  
      
      
  
 
 
  
   
  
 
 
 
 
 
 
 
 
 
 
   
  
 
 
 
 
 
  
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
  
 
 
 
  
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
  
 
 
 
 
 
 
 
 
  
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
LUMINEX CORPORATION  
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS  

NOTE 1 — DESCRIPTION OF BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES  

Description of Business  

Luminex  Corporation  (the  “Company”  or  “Luminex”)  develops,  manufactures  and  sells  proprietary  biological  testing 
technologies  and  products  with  applications  throughout  the  life  sciences  and  diagnostic  industries.  The  Company’s  xMAP®
technology,  an  open  architecture,  multiplexing  technology,  allows  the  Luminex  systems  to  simultaneously  perform  up  to  500 
bioassays from a small sample volume, typically a single drop of fluid, by reading biological tests on the surface of microscopic 
polystyrene beads called microspheres. xMAP technology combines this miniaturized liquid array bioassay capability with small 
lasers, digital signal  processors  and  proprietary software to create a system  offering  advantages in speed,  precision,  flexibility 
and cost. The Company’s xMAP technology is currently being used within various segments of the life sciences industry which 
includes  the fields of drug  discovery and  development,  clinical  diagnostics, genetic  analysis,  bio-defense,  protein analysis  and 
biomedical research.  

Principles of Consolidation  

The  consolidated  financial  statements  include  the  accounts  of  the  Company  and  its  wholly  owned  subsidiaries.  All 
significant  intercompany  transactions  and balances have  been  eliminated  upon  consolidation. Certain  prior year  amounts have 
been reclassified to conform to the current year presentation.  

The acquisition of Tm Bioscience Corporation, or Tm, now known as Luminex Molecular Diagnostics, Inc., or LMD, was 
completed  on  March 1, 2007;  therefore, the  results of  operations of  LMD  in  the  Company’s consolidated  financial  statements 
only include LMD results since that date.  

Adoption of the FASB Accounting Standards Codification  

In  June 2009,  the  FASB  issued  ASC  Update  No. 2009-01  (ASU  No. 2009-01),  “Topic  105  —  Generally  Accepted 
Accounting Principles,” which amends the ASC for the issuance of Statement of Financial Accounting Standards No. 168 (SFAS 
No. 168),  “The  FASB  Accounting  Standards  Codification  and  the  Hierarchy  of  Generally  Accepted  Accounting  Principles.”
ASU  No. 2009-01  includes  SFAS  No. 168  in  its  entirety  and  establishes  the  ASC  as  the  source  of  authoritative  accounting 
principles  recognized  by  FASB  for  all  nongovernmental  entities  in  the  preparation  of  financial  statements  in  accordance  with 
GAAP.  For  SEC  registrants,  rules  and  interpretive  releases  of  the  SEC  under  federal  securities  laws  are  also  considered 
authoritative sources of GAAP. The guidance is effective for financial statements issued for interim and annual periods ending 
after September 15, 2009. The Company adopted the FASB ASC for fiscal year ended December 31, 2009. The adoption had no 
impact on the Company’s financial statements. All references to authoritative guidance have been updated to cite relevant ASC 
Topics, as applicable.  

Use of Estimates  

The  preparation  of  financial  statements  in  conformity  with  accounting  principles  generally  accepted  in  the  United  States 
requires  management  to  make  estimates  and  assumptions  that  affect  the  amounts  reported  in  the  financial  statements  and 
accompanying notes. Actual amounts and results could differ from those estimates, and such differences could be material to the 
financial statements.  

Subsequent Events  

The  Company  has  evaluated  subsequent  events through  the  time  of  filing  this Form  10-K with the  SEC on  February 25, 
2010.  No  material  subsequent  events  have  occurred  since  December 31,  2009  that  required  recognition  or  disclosure  in  these 
financial statements.  

63

                                   
   
Cash and Cash Equivalents  

Cash and cash equivalents consist of cash deposits and highly liquid investments with original maturities of three months or 

less when purchased.  

Investments  

The  Company  determines  the  appropriate  classification  of  its  investments  in  debt  and  equity  securities  at  the  time  of 
purchase and reevaluates such determinations at each balance sheet date. Debt securities are classified as held-to-maturity when 
the Company has the positive intent and ability to hold the securities to maturity. Debt securities for which the Company does 
not  have  the  intent  or  ability  to  hold  to  maturity  are  classified  as  available  for  sale.  Held-to-maturity  securities  are  stated  at 
amortized cost, which approximates fair value of these investments. Marketable securities that are bought and held principally 
for the purpose of selling them in the near term are classified as trading securities and are reported at fair value, with unrealized 
gains and losses recognized in earnings. Debt and marketable equity securities not classified as held-to-maturity or as trading are 
classified  as  available  for  sale,  and  are  carried  at  fair  market  value,  with  the  unrealized  gains  and  losses  included  in  the 
determination of comprehensive income and reported in stockholders’ equity. Marketable securities are recorded as either short-
term or long-term on the balance sheet based on contractual maturity date. The fair value of all securities is determined by quoted 
market prices and market interest rates as of the end of the reporting period. Declines in fair value below the Company’s carrying 
value deemed to be other than temporary are charged against net earnings.  

Fair Value of Financial Instruments  

The fair values of financial instruments are determined based on  quoted market prices and market  interest rates as of the 
end  of  the  reporting  period.  The  Company’s  financial  instruments  include  cash  and  cash  equivalents,  short-term  investments, 
accounts receivable, long-term investments, accounts payable, accrued liabilities, and long-term debt. Except for the fair value of 
the Company’s long-term debt, the fair values of these financial instruments were not materially different from their carrying or 
contract values at December 31, 2009 and 2008. See Note 11 for further details concerning the fair value of the Company’s long-
term debt.  

Concentration of Credit Risk  

Financial instruments which potentially subject the Company to concentrations of credit risk consist of short-term and long-
term  investments  and  trade  receivables.  The  Company’s  short-term  investments  consist  of  investments  in  high  credit  quality 
financial institutions and corporate issuers.  

The  Company  provides  credit,  in  the  normal  course  of  business,  to  a  number  of  its  customers  geographically  dispersed 
primarily  throughout  the  U.S.  The  Company  attempts  to  limit  its  credit  risk  by  performing  ongoing  credit  evaluations  of  its 
customers and maintaining adequate allowances for potential credit losses and does not require collateral.  

One Lambda, Inc. accounted for 21%, 24% and 18% of the Company’s total technology segment revenues in 2009, 2008 
and  2007,  respectively.  Bio-Rad  Laboratories,  Inc.  accounted  for  16%,  21%  and  24%  of  the  Company’s  total  technology 
segment  revenues  in  2009,  2008  and  2007,  respectively.  Fisher  Scientific  accounted  for  31%,  21%  and  less  than  10%  of  the 
Company’s  total  assay  segment  revenues  in  2009,  2008  and  2007,  respectively.  Abbott  Laboratories  accounted  for  21%,  less 
than 10%, and less than 10% of the Company’s total assay segment revenues in 2009, 2008 and 2007, respectively. Genzyme 
Genetics  accounted  for  15%,  27%,  and  33%  of  the  Company’s  total  assay  segment  revenues  in  2009,  2008  and  2007, 
respectively. LabCorp accounted for less than 10%, less than 10%, and 13% of the Company’s total assay segment revenues in 
2009, 2008 and 2007, respectively. No other customer accounted for more than 10% of total segment revenues in 2009, 2008 or 
2007.  

64

                                   
   
Inventories  

Inventories, consisting primarily of raw materials and purchased components, are stated at the lower of cost or market, with 
cost  determined  according  to  the  standard  cost  method.  The  Company  routinely  assesses  its  on-hand  inventory  for  timely 
identification and measurement of obsolete, slow-moving or otherwise impaired inventory.  

Property and Equipment  

Property  and  equipment  are  carried  at  cost  less  accumulated  amounts  for  amortization  and  depreciation.  Property  and 
equipment are generally amortized or depreciated on a straight-line basis over the useful lives of the assets, which range from 
two to seven years. Leasehold improvements and equipment under capital lease are amortized on a straight-line basis over the 
shorter  of  the  remaining  term  of  the  lease  or  the  estimated  useful  life  of  the  improvements  and  equipment.  The  Company 
classifies the carrying value of Luminex xMAP™ Instruments placed within the reagent rental program and the instruments on 
loan to customers in Property and equipment as “Assets on loan/rental”.  

Goodwill and Other Intangible Assets  

Goodwill represents the excess of the cost over the fair value of the assets of the acquired business. In accordance with ASC 
350  “Goodwill  and  Other”  (ASC  350),  goodwill  is  reviewed  for  impairment  at  least  annually  at  the  beginning  of  the  fourth 
quarter,  or  more  frequently  if  impairment  indicators  arise,  on  a  reporting  unit  level.  The  Company  allocates  goodwill  to  one 
reporting unit, the assay segment, for goodwill impairment testing. In performing the impairment test, the Company utilizes the 
two-step approach prescribed under the ASC. The first step requires a comparison of the carrying value of the reporting unit to 
the estimated fair value of the reporting unit. If in step one of the annual test, the carrying amount of a reporting unit exceeds its 
fair  value,  then  a  goodwill  impairment  test  is  performed  in  step  two  to  measure  the  amount  of  the  impairment  loss,  if  any. 
Determining  the  fair  value  of  goodwill  is  subjective  in  nature  and  often  involves  the  use  of  estimates  and  assumptions.  The 
Company utilizes the income approach based on a discounted cash flow analysis to determine its fair value estimates, and then 
uses market comparisons as a reasonability check to ensure that neither the income approach nor the market comparisons yielded 
significantly different results. The income approach is based on a discounted cash flow analysis and calculates the fair value by 
estimating the after-tax cash flows attributable to a reporting unit and then discounting the after-tax cash flows to a present value 
using  a  risk-adjusted  discount  rate.  As  the  Company’s  assay  segment  and  goodwill  came  into  existence  in  2007  due  to  the 
acquisition of Tm Biosciences, now referred to as LMD, the Company believes that the DCF method best aligns with how the 
Company approached the acquisition and determined the value of the acquired company. This methodology used to determine 
fair value has been consistently applied since the inception of the Company’s goodwill in 2007; however, the assumptions and 
estimates  are  updated  each  year.  The  Company’s  estimates  are  based  on  revenue  projections  by  product  line,  and  include 
judgment based  on historical  growth  and scheduled  product approvals  by the  various  governmental  authorities.  The  Company 
believes  its  assumptions  are  consistent  with  the  plans  and  estimates  used  to  manage  the  underlying  businesses.  The  most 
significant assumptions used in the discounted cash flow methodology are the discount rate, based upon the estimated weighted 
average cost of capital (WACC), and the terminal growth rate, based upon strategic studies the Company commissioned and the 
Company’s own internal  analysis.  A WACC rate of 15.2% and a terminal growth  rate of 4.4% were  used by the Company  in 
2009.  

To determine the Company’s WACC rate, the Company performed a peer company analysis and considered the weighted 
average  return  on  debt  and  equity,  the  updated  risk-free  interest  rate,  beta,  equity  risk  premium,  and  entity  specific  size  risk 
premium.  The  Company’s  terminal  growth  rates  are  based  upon  market  estimates  provided  in  strategic  studies  previously 
commissioned  by  the  Company  and  the  Company’s  own  internal  analysis.  The  Company’s  analysis  yielded  an  estimated  fair 
value in excess of the carrying value by over 50% for 2009.  

Concurrent with the above analysis, the Company performed a sensitivity analysis based upon reasonably likely changes to 
determine  if  the  Company’s  DCF  analysis  would  result in  impairment  if  the  following  changes  were  made  to the  Company’s 
assumptions:  i)  assumed  WACC  rate  was  increased  by  5 percentage  points;  ii)  future  revenue  was  75%  of  the  Company’s 
projections in the DCF model; or iii) the terminal growth rate used was 50% lower. None of these sensitivity analyses resulted in 
an estimated fair value less than the carrying amount of the reporting unit. No goodwill impairments were recorded in 2009 or 
2008.  

65

                                   
   
Intangible  assets  are  amortized  on  a  straight  line  basis  over  their  respective  estimated  useful  lives  ranging  from  2  to 
15 years. The useful lives of the assets acquired as part of the Tm acquisition were established as a result of the allocation of fair 
values at March 1, 2007. The Company has no intangible assets with indefinite useful lives.  

Impairment of Long-Lived Assets  

Long-lived assets held and used by the Company are reviewed for impairment whenever events or changes in circumstances 
indicate that their net book value may not be recoverable. When such factors and circumstances exist, the Company compares 
the projected undiscounted future cash flows associated with the related asset or group of assets over their estimated useful lives 
against their respective carrying amounts. Impairment, if any, is based on the excess of the carrying amount over the fair value of 
those assets and is recorded in the period in which the determination was made.  

Revenue Recognition and Allowance For Doubtful Accounts  

Revenue from sales of the Company’s products is recognized when persuasive evidence of an agreement exists, delivery of 
the product has occurred, the fee is fixed and determinable and collectability is probable. Generally, these criteria are met at the 
time the product is shipped. If the criteria for revenue recognition are not met at the time of shipment, the revenue is deferred 
until  all  criteria  are  met.  Revenues  from  royalties  related  to  agreements  with  strategic  partners  are  recognized  when  such 
amounts are reported to the Company; therefore, the underlying end  user sales  may  be related  to prior  periods. Revenue from 
extended service agreements is deferred and recognized ratably over the term of the agreement. Revenues from contracts with 
multiple elements are recognized as each element is earned based on the relative fair value of each element when there are no 
undelivered elements that are essential to the functionality of the delivered elements and when the amount is not contingent upon 
delivery  of  the  undelivered  elements.  Amounts  billed  or  collected  in  excess  of  revenue  recognized  are  recorded  as  deferred 
revenue.  

The Company continuously monitors collections and payments from its customers and maintains allowances for doubtful 
accounts based upon its historical experience and any specific customer collection issues that have been identified. While such 
credit  losses  have  historically  been  within  the  Company’s  expectations,  there  can  be  no  assurance  that  the  Company  will
continue  to  experience  the  same level  of  credit losses  that  it  has in  the  past.  A significant  change  in  the  liquidity  or financial 
position of any one of the Company’s significant customers, or a deterioration in the economic environment, in general, could 
have  a  material  adverse  impact  on  the  collectability  of  the  Company’s  accounts  receivable  and  its  future  operating  results, 
including a reduction in future revenues and additional allowances for doubtful accounts.  

Product-Related Expenses  

The  Company  provides  for  the  estimated  cost  of  initial  product  warranties  at  the  time  revenue  is  recognized.  While  the 
Company engages in product quality programs and processes, the Company’s warranty obligation is affected by product failure 
rates,  material  usage  and  service  delivery  costs  incurred  in  correcting  a  product  failure.  Should  actual  product  failure  rates, 
material usage or service delivery costs differ from the Company’s estimates, revisions to the estimated warranty liability would 
be  required.  Shipping  and  handling  costs  associated  with  product  sales  are  included  in  cost  of  sales.  The  Company  expenses 
advertising costs as incurred. Advertising expenses were not significant for any of the years presented.  

Research and Development Costs  

Research and development costs are generally expensed in the period incurred; however, the Company capitalizes certain 
internally  developed  products,  used  for  evaluation  during  development  projects  that  also  have  alternative  future  uses.  These 
assets are generally  depreciated on a straight-line basis over the  useful life  of  the assets  which  range  from two  months to  one 
year. The Company did not capitalize any material research and development costs in 2009 or 2008.  

66

                                   
   
Incentive Compensation  

Management  incentive  plans  are  tied  to  various  financial  and  non-financial  performance  metrics.  Bonus  accruals  made 
throughout  the year  related to the  various incentive plans  are based  on  management’s best  estimate of the  achievement  of the 
specific metrics. Adjustments to the accruals are made on a quarterly basis as forecasts of performance are updated. At year-end, 
the accruals are adjusted to reflect the actual results achieved.  

Income Taxes  

The Company accounts for income under the asset and liability method. Deferred tax assets and liabilities are recognized 
for the estimated future tax consequences attributable to differences between the financial statement carrying amounts of existing 
assets  and  liabilities  and  their  respective  tax  bases.  Deferred  tax  balances  are  adjusted  to  reflect  tax  rates  based  on  currently 
enacted tax laws, which will be in effect in the years in which the temporary differences are expected to reverse. The effect on 
deferred tax assets and liabilities of a change in tax rates is recognized in the results of operations in the period of the enactment 
date. A valuation allowance is recorded to reduce the carrying amounts of deferred tax assets unless it is more likely than not that 
such assets will be realized.  

The Company recognizes excess tax benefits associated with share-based compensation to stockholders’ equity only when 
realized.  When  assessing  whether  excess  tax  benefits  relating  to  share-based  compensation  have  been  realized,  the  Company 
follows the with-and-without approach, excluding any indirect effects of the excess tax deductions. Under this approach, excess 
tax benefits related to share-based compensation are not deemed to be realized until after the utilization of all other tax benefits 
available to the Company.  

Effective January 1, 2007, the Company adopted ASC 740, which clarifies the accounting for uncertainty in tax positions. 
These provisions require recognition of the impact of a tax position in the Company’s financial statements only if that position is 
more  likely than  not  of  being  sustained  upon  examination by  taxing authorities, based  on the  technical  merits  of  the position. 
Any interest and penalties related to uncertain tax positions will be reflected in income tax expense.  

Earnings Per Share  

Basic  net  income  (loss) per  share  is  computed  by  dividing  the  net  income  (loss) for  the  period  by  the  weighted  average 
number of common  shares outstanding during the  period.  Diluted net  income  (loss) per share  is  computed  by  dividing  the net 
income (loss) for the period by the weighted average number of common and common equivalent shares outstanding during the 
period. Potentially dilutive securities composed of incremental common shares issuable upon the exercise of stock options and 
warrants,  and  common  shares  issuable  on  conversion  of  preferred  stock,  were  excluded  from  historical  diluted  loss  per  share 
because of their anti-dilutive effect.  

Stock-Based Compensation  

The  Company  accounts  for  stock-based  employee  compensation plans  under  the  fair  value recognition  and  measurement 
provisions of ASC 718 “Stock Compensation” (ASC 718). ASC 718 requires the recognition of compensation expense, using a 
fair-value based method, for costs related to all share-based payments including stock options. Pursuant to ASC 718, stock-based 
compensation  cost  is  measured  at  the  grant  date,  based on  the  fair  value  of  the  award,  and  is  recognized  as  expense  over  the 
requisite service period.  

Segment Reporting  

Historically  the  Company  had  operated  as  a  single  segment.  Subsequent  to  the  acquisition  of  LMD,  management 
determined that the Company has two segments for financial reporting purposes: the technology segment and the assay segment. 
See Note 17 — Segment and Geographic Information.  

67  

                                   
   
NOTE 2 — BUSINESS COMBINATIONS  

Acquisition  

On  March 1,  2007,  the  Company  completed  the  acquisition  of  Tm,  a  DNA-based  research  and  diagnostics  company 
headquartered in Toronto, Canada. Prior to the acquisition, Tm was one of the Company’s strategic partners. All intercompany 
balances were eliminated upon acquisition. The Company believes this acquisition is a logical extension of its strategy and that 
the combined Company will be in a position to take advantage of the complementary strengths of both companies in molecular 
diagnostics. The acquired company is referred to as LMD and is included in the Company’s assay segment for financial reporting 
purposes. The focus of LMD is to design, develop, manufacture and commercialize nucleic-acid based testing products for use in 
the genetic testing, personalized medicine and infectious disease markets.  

Upon the closing of the acquisition, the Company exchanged 0.06 shares of Luminex common stock for each outstanding 
Tm  share,  which  resulted  in  the  issuance  of  approximately  3.2 million  shares  of  Luminex  common  stock.  The  value  of  the 
approximately 3.2 million common shares issued was determined based on the average market price of the Company’s common 
stock  over  the  period  including  five  days  before  and  after  the  terms  of  the  acquisition  were  agreed  to  and  announced  in 
accordance  with  ASC  805  “Business  Combinations”  (ASC  805).  The  Company  also  agreed  to  assume  the  outstanding  Tm 
options according to  the applicable Tm  plan  provisions  and the outstanding warrants. At the date of acquisition, these options 
and  warrants  were  potentially  exercisable  for  approximately  694,000  additional  shares  of  Luminex  common  stock  on  an  as-
converted basis. The estimated fair value of Luminex’ replacement options and warrants was calculated using the Black-Scholes 
model.  In  accordance  with  ASC  718,  the  portion  of  the  estimated  fair  value  of  unvested  Tm  options  related  to  future  service 
(approximately $242,000) was deducted from the purchase price consideration and will be recognized as compensation expense 
over  those  awards’  remaining  vesting  period.  As  of  December 31,  2009,  there  were  replacement  options  outstanding  for  the 
purchase  of  68,414  shares  of  Luminex  common  stock  with  exercise  prices  ranging  from  $11.12  to  $44.88  and  replacement 
warrants outstanding for the purchase of approximately 288,000 shares of Luminex common stock with exercise prices ranging 
from $10.12 to $37.18. All of the warrants are exercisable as of December 31, 2009.  

Immediately  subsequent  to  the  acquisition,  the  Company  retired  approximately  $13.2 million  of  Tm  debt,  including  an 
approximately  $1.0 million  contractual  penalty,  by  using  existing  cash  reserves.  Under  the  terms  of  one  of  the  retired  debt 
instruments, the balance of the note became callable upon the acquisition and was subject to a contractual penalty if either called 
by  the  debt  holder  or  prepaid  by  Tm.  The  penalty  was  triggered  when  the  Tm  shareholders  ratified  the  acquisition  of  Tm  by 
Luminex  on  February 21,  2007.  The penalty  was  recorded  by  Tm  prior to  Luminex’ acquisition  based  on the  penalty  amount 
agreed by the debt holder, and was reflected in the opening balance of “Other current liabilities assumed.”  

The  acquisition  was  accounted  for  as  a  purchase  business  combination  in  accordance  with  ASC  805.  LMD  results  of 
operations are included with the Company’s from the date of acquisition, March 1, 2007. The purchase price of the acquisition 
was  approximately  $49.4 million,  including  the  issuance  of  common  stock  valued  at  $41.8 million  and  transaction  costs  of 
approximately $3.6 million. The purchase price has been allocated to the net assets acquired based on estimates of the fair values 
at the date of the acquisition.  

In 2007, Luminex completed the process of allocating fair values for certain tangible and intangible assets and in-process 
research and development (IPR&D) identified during the acquisition. The acquired intangible assets were allocated to the assay 
segment. The excess purchase price over the fair values of the net tangible assets, identified intangible assets and liabilities was 
allocated  to  goodwill.  Luminex  recorded  $39.6 million  of  goodwill  related  to  the  Tm  acquisition  in  the  Company’s  assay 
segment. Goodwill is not expected to be deductible for tax purposes.  

68

                                   
   
The  following  table  summarizes  the  estimated  fair  values  of  net  assets  at  the  date  of  acquisition  (in  thousands).  Certain 
tangible and intangible assets and liabilities were adjusted to their estimated fair market values upon the final analysis of these 
values  during  the  fourth  quarter.  Based  on  ASC  805,  the  following  intangible  assets  evaluated  were:  trade  name  (Tag-It), 
customer  list/contracts,  technology/trade  secrets,  and  in-process  research  and  development.  IPR&D  has  been  recorded  at  its
estimated fair market value and charged to expense in 2007.  

Cash 
Other current assets 
Other assets 
Property and equipment 
Purchased intangible assets 
In-process research and development
Goodwill 
Total assets 

Current portion of debt assumed 
Accrued severance assumed 
Other current liabilities assumed 
Long-term debt assumed 
Other long-term liabilities assumed 
Total liabilities 

Purchase price 

Pro Forma Information  

$

$

$

940
3,157
28
3,518
18,800 
7,400
39,617
73,460

12,447
1,945
7,148 
2,294
225
24,059

$

49,401

The financial information in the table below summarizes the combined results of operations of Luminex and LMD, on a pro 

forma basis, as though the companies had been combined at the beginning of 2007.  

The  pro  forma  financial  information  is  presented  for  informational  purposes  only  and  is  not  indicative  of  the  results  of 

operation that would have been achieved if the acquisition of LMD had taken place at the beginning of fiscal 2007.  

The following table summarizes the pro forma financial information for the year ended December 31, 2007 (in thousands, 

except per share amounts):  

Revenues 
Net loss 
Net loss per share, basic and diluted 

In-process Research and Development (IPR&D)  

2007

75,328
(8,488)
(0.25)

$
$
$

In conjunction with the acquisition of LMD in 2007, the Company has recorded total IPR&D expense of $7.4 million for 

acquired IPR&D which was not technologically feasible as of the acquisition date and had no alternative future use.  

69

                                   
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
   
 
 
 
  
 
   
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
   
 
 
 
  
 
   
 
   
 
 
 
 
 
   
 
 
 
 
 
NOTE 3 — INVESTMENTS  

Held-to-maturity securities as of December 31, 2009 consisted of government sponsored debt obligations of $42.8 million.  

Held-to-maturity securities consisted of the following as of December 31, 2009 (in thousands):  

Due in one year or less 
Due after one year through two years

Total held-to-maturity securities 

Cost

Accrued    
Interest

    Amortized Cost

$

$

40,501   
2,000

42,501

$

$

283   
20   

303   

$
$

$

40,784 
2,020

42,804

Available-for-sale securities consisted of the following as of December 31, 2009 (in thousands):  

Gains in
Accumulated
Other
Comprehensive
Gain (Loss)

Losses in

Accumulated   

Other

Comprehensive   Estimated
   Fair Value

Gain (Loss)

  Amortized

Cost

Current: 

Money Market funds 
Non-government sponsored debt securities 

Total current securities 

$

$

60,299
33,495
93,794

Noncurrent: 

Non-government sponsored debt securities 
Government sponsored debt securities

Total noncurrent securities 

18,144
2,035
20,179

— $
19
19

72
12
84

$

—  
(5) 
(5) 

60,299
33,509
93,808

(35) 
—  
(35) 

18,181
2,047
20,228

Total available-for-sale securities 

$ 113,973

$

103

$

(40) 

$

114,036

There were no proceeds from the sales of available-for-sale securities during the year ended December 31, 2009 or 2008. 
Net  unrealized  holding  gains  and  losses  of  $63,000  on  available-for-sale  securities  have  been  included  in  accumulated  other 
comprehensive gain (loss).  

The estimated fair value of available-for-sale debt securities at December 31, 2009, by contractual maturity, was as follows 

(in thousands):  

Due in one year or less 
Due after one year through two years

Estimated
Fair Value

$

$

33,509
20,228
53,737

Expected maturities may differ from contractual maturities because the issuers of the securities may have the right to prepay 

obligations without prepayment penalties.  

70

                                   
   
 
   
   
 
 
  
   
   
 
   
 
 
 
 
 
 
 
 
  
   
   
   
 
 
 
 
 
 
 
 
 
 
  
   
 
 
  
 
 
 
 
  
 
 
 
  
 
  
   
 
  
   
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
  
   
 
  
   
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
  
   
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
   
 
 
 
   
 
 
 
  
 
   
 
 
 
The  Fair  Value  Measurements  and  Disclosures  Topic  of  the  FASB  ASC  defines  fair  value,  establishes  a  framework  for 
measuring  fair  value  under generally  accepted  accounting principles  and  enhances  disclosures  about  fair  value  measurements. 
Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the 
principal  or  most  advantageous  market  for  the  asset  or  liability  in  an  orderly  transaction  between  market  participants  on  the 
measurement date. Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize 
the use of unobservable inputs. The ASC describes a fair value hierarchy based on the following three levels of inputs that may 
be used to measure fair value, of which the first two are considered observable and the last unobservable:  

Level 1—Quoted prices in active markets for identical assets or liabilities.  

Level 2—Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets 
or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable 
market data for substantially the full term of the assets or liabilities.  

Level 3—Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of 

the assets or liabilities.  

The  following  table  represents  the  Company’s  fair  value  hierarchy  for  its  financial  assets  (cash  equivalents  and 

investments) measured at fair value on a recurring basis as of December 31, 2009 (in thousands):  

Fair Value Measurements at Reporting Date Using

Level 1

Level 2

Level 3

Total

Money Market funds 
Non-government sponsored debt securities 
Government sponsored debt securities

Total 

Amounts included in: 
Cash and cash equivalents 
Short-term investments 
Long-term investments 

Total 

—   

—

—

—   
—
—

—

—   

$

—   

60,299 
51,690
2,047

—   

$

114,036

$

—   
—   
—   

85,297 
8,511
20,228

—   

$

114,036

$

$

$

60,299   
51,690
2,047

114,036

85,297   
8,511
20,228

$

114,036

71

                                   
   
 
 
   
   
 
 
   
 
 
 
 
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
  
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
  
 
   
   
 
   
   
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
  
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
NOTE 4 — ACCOUNTS RECEIVABLE  

Accounts receivable consisted of the following at December 31 (in thousands):  

2009

2008

Accounts receivable 
Less: Allowance for doubtful accounts

$

$

22,631   
(523)  

22,108   

The following table summarizes the changes in the allowance for doubtful accounts (in thousands):  

Balance at December 31, 2006 

Reductions charged to costs and expenses 
Write-offs of uncollectible accounts
Additions due to acquired accounts receivable 
Recoveries of uncollectible accounts

Balance at December 31, 2007 

Reductions charged to costs and expenses 
Write-offs of uncollectible accounts
Recoveries of uncollectible accounts

Balance at December 31, 2008 

Reductions charged to costs and expenses 
Write-offs of uncollectible accounts
Increase in allowance charged to expense 
Recoveries of uncollectible accounts

Balance at December 31, 2009 

NOTE 5 — INVENTORY, NET  

Inventory consisted of the following at December 31 (in thousands):  

Parts and supplies 
Work-in-progress 
Finished goods 

2009

$

9,499   
4,064   
3,961   
17,524   

$

$

$

$

$

$

$

11,296 
(272)

11,024

301
—
(1)
56 
—

356
(50)
(34)
—

272
— 
(7)
258
—

523

2008

5,213
3,939
2,437 
11,589

The  Company  has  non-cancelable  purchase  commitments  with  certain  of  its  component  suppliers  in  the  amount  of 
approximately  $12.7 million  at  December 31,  2009.  Should  production  requirements  fall  below  the  level  of  the  Company’s 
commitments,  the  Company  could  be  required  to  take  delivery  of  inventory  for  which  it  has  no  immediate  need  or  incur  an 
increased cost per unit going forward.  

72

                                   
   
 
 
   
   
 
   
  
 
   
   
 
 
   
 
 
 
 
 
  
 
   
   
  
   
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
   
 
 
 
  
 
   
 
 
 
 
 
 
 
   
 
 
 
  
 
   
 
 
 
 
 
 
 
 
 
  
 
   
 
   
 
 
 
 
 
   
   
 
   
 
 
 
 
 
 
   
 
 
 
 
 
  
 
   
 
 
 
 
 
NOTE 6 — PROPERTY AND EQUIPMENT  

Property and equipment consisted of the following at December 31 (in thousands):  

Laboratory equipment 
Leasehold improvements 
Computer equipment 
Purchased software 
Furniture and fixtures 
Assets on loan/rental 
Capital lease equipment 

Less: Accumulated amortization and depreciation 

2009

2008

$

$

12,389   
9,317   
3,602   
7,172   
3,524   
1,849   
116   

9,223 
6,550
3,071
5,521
1,609
1,516
116

37,969   
(20,714)  

27,606
(15,039)

$

17,255   

$

12,567

Depreciation expense was $5.7 million,  $4.5 million, and $3.0 million for the years ended December 31,  2009,  2008, and

2007, respectively.  

NOTE 7 — ACQUIRED INTANGIBLE ASSETS  

Amortized identifiable intangible assets consisted of the following at December 31 (in thousands except weighted average

lives):  

2009

2008

Technology/trade secrets 
Customer lists/contracts 
Total 

  $

  $

  Gross carrying   Accumulated Weighted Gross carrying   Accumulated   Weighted
   amortization    average life

amount

amount

   amortization
(5,355)
(208)
(5,563)

17,400   $
1,100    
18,500   $

average life
9
15

$

$

17,400   $
1,100    
18,500   $

(3,465) 
(134) 
(3,599)   

9
15

The amortization expense related to purchased intangible assets was approximately $2.0 million for both of the years ended
December 31, 2009 and 2008. The estimated aggregate amortization expense for the next five years is as follows (in thousands): 

2010 
2011 
2012 
2013 
2014 

$

1,963
1,963
1,963
1,963
1,963

73

                                   
   
 
 
   
   
 
   
  
 
   
   
 
 
 
 
 
 
 
   
 
 
 
 
 
  
 
   
   
  
 
 
   
 
 
 
 
 
  
 
   
   
  
   
 
 
 
 
 
 
 
      
      
    
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
NOTE 8 — OTHER ASSETS  

Other assets consisted of the following at December 31 (in thousands):  

Purchased technology rights (net of accumulated amortization of $1,215,000 and $548,000 

in 2009 and 2008, respectively) 

Other 

Less: Current portion 

2009

2008

$

817   
288   

$

1,105   
(18)  

1,300
353

1,653 
(114)

$

1,087   

$

1,539

For  the  years  ended  December 31,  2009  and  2008,  the  Company  recognized  amortization  expense  related  to  the 
amortization  of  these  acquired  technology  rights  of  approximately  $667,000  and  $440,000,  respectively.  Future  amortization 
expense  will  be  $129,000  in  2010,  $110,000  in  2011,  $107,000  in  2012,  $94,000  in  2013,  $85,000  in  2014,  and  $293,000 
thereafter.  

NOTE 9 — ACCRUED WARRANTY COSTS  

Sales  of  certain  of  the  Company’s  systems  are  subject  to  a  warranty.  System  warranties  typically  extend  for  a  period  of 
twelve months from the date of installation or no more than 15 months from the date of shipment. The Company estimates the 
amount  of  warranty  claims  on  sold  products  that  may  be  incurred  based  on  current  and  historical  data.  The  actual  warranty 
expense could differ from the estimates made by the Company based on product performance. Warranty expenses are evaluated 
and adjusted periodically.  

The following table summarizes the changes in the warranty accrual (in thousands):  

Accrued warranty costs at December 31, 2006 
Warranty expenses 
Accrual for warranty costs 
Accrued warranty costs at December 31, 2007 
Warranty expenses 
Accrual for warranty costs 
Accrued warranty costs at December 31, 2008 
Warranty expenses 
Accrual for warranty costs 
Accrued warranty costs at December 31, 2009 

NOTE 10 — INCOME TAXES  

$

$

311
(525)
473
259
(946)
1,166 
479
(1,003)
1,105
581

The components of income (loss) before income taxes for the years ended December 31 are as follows (in thousands):  

Domestic 
Foreign 

Total 

2009

2008

$

$

8,236   
(4,949)
3,287

$

$

13,021   
(9,116)  
3,905   

$

$

2007

12,164 
(14,585)
(2,421)

74

                                   
   
 
 
   
   
 
   
  
 
   
   
 
   
 
 
 
 
 
  
 
   
   
  
 
 
 
 
   
 
 
 
 
 
  
 
   
   
  
   
 
 
 
 
 
 
 
   
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
   
 
 
 
 
   
 
 
 
 
 
   
   
 
   
 
 
   
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
The  components  of  the  provision  (benefit) for  income  taxes  attributable  to  continuing  operations  for  the  years  ended

December 31 are as follows (in thousands):  

Current: 

Federal 
Foreign 
State 
Total current 

Deferred: 
Federal 
Foreign 
State 
Total deferred 

Total provision for income taxes 

2009

2008

2007

$

$

$

194
(41)
295
448

(13,263)
—
(1,627)  
(14,890)
(14,442)  

$

$

$

308   
146   
394   
848   

—   
—   
—   
—   
848   

$

$

$

177
84
29
290

—
—
— 
—
290 

The  provision  (benefit) for  income  taxes  differs  from  amount  computed  by  applying  the  statutory  federal  rate  to  pretax

income (loss) as follows (in percentages):  

Statutory tax rate 
State taxes, net of federal benefit 
Permanent items 
Effect of foreign operations 
Research and incentive tax credit generated 
Canadian tax rate change 
Valuation allowance 
Other 

Year Ended December 31,
2008

2007

2009

35.0%
5.7%
25.5%
0.2%
(48.4)% 
0.0%
(451.2)%
(6.0)%
(439.2)% 

35.0%  
7.3%  
16.0%  
(0.6)% 
(21.9)% 
0.0%  
(14.4)% 
0.0%  
21.4%  

34.0%
3.6%
(21.2)%
14.7%
35.8%
(64.8)%
(11.4)%
0.0%
(9.3)%

75

                                   
   
 
 
   
   
 
   
 
   
   
 
 
   
 
 
 
 
 
 
 
 
  
 
   
   
 
   
   
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
   
 
   
 
 
 
   
 
   
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
  
 
 
 
 
   
 
 
 
 
 
 
 
 
 
Deferred  income  taxes  reflect  the  net  tax  effects  of  temporary  differences  between  the  carrying  amounts  of  assets  and 
liabilities  for  financial  reporting  purposes  and  the  amounts  used  for  income  tax  purposes.  Significant  components  of  the 
Company’s deferred tax assets and liabilities as of December 31 are as follows (in thousands):  

Deferred tax assets: 

Current deferred tax assets 

Accrued Liabilities and other 
Gross current deferred tax assets 
Valuation allowance 
Net current deferred tax assets 
Noncurrent deferred tax assets 

Net operating loss and credit carryforwards 
Deferred revenue 
Depreciation and amortization 
Stock compensation 
Gross Noncurrent Deferred Tax Assets 
Valuation allowance 

Net noncurrent deferred tax assets

Deferred tax liabilities: 

Current deferred tax liabilities 

Accrued Liabilities and other 
Total current deferred tax liabilities 
Net current deferred tax asset 
Noncurrent deferred tax liabilities 

Acquired intangibles 

Total noncurrent deferred tax liabilities 
Net noncurrent deferred tax asset 
Net deferred tax assets 

2009

2008

2007

$

$

$

$

$
$
$
$

2,323
2,323
(801)
1,522   

53,528
2,906
3,099
1,922
61,455
(42,575)
18,880

(482)
(482)  
1,040

(4,148)
(4,148)
14,732
15,772

$

$

$

$
$
$
$

908   
908   
(906)  
2   

49,726   
2,835   
6,924   
3,191   
62,676   
(57,577)  
5,099   

—   
—   
2   

(4,825)  
(4,825)  
274   
276   

$

$

$

$
$
$
$

1,061
1,061
(1,059)
2 

54,168
2,535
7,902
1,981
66,586
(60,944)
5,642

—
— 
2

(5,521)
(5,521)
121
123

The valuation allowance decreased by $15.3 million in fiscal year 2009 and decreased by $3.4 million in fiscal year 2008. 
During fiscal year 2009, the Company released approximately $14.9 million of the valuation allowance that had been placed on 
its  U.S.  deferred  tax  assets  that  impacted  the  effective  tax  rate.  The  Company  recorded  an  additional  amount  of  valuation 
allowance  related  to  the  provision  for  the  Canadian  subsidiary  of  approximately  $1.0 million.  The  remaining  decrease  in  the 
valuation allowance of approximately $1.4 million was the reversal of certain deferred tax assets and the corresponding valuation 
allowance  such  that  there  was  no  impact  to  the  Company’s  income  tax  provision  (benefit).  Based  on  the  Company’s  recent 
history of generating income in the U.S. and the Company’s expectation to continue to generate future income in the U.S., the 
Company determined that it was  more  likely  than  not  that  the $14.9 million  of  U.S.  deferred tax  assets  would  be  realized. At 
December 31,  2009,  the  Company  had  federal  net  operating  losses  carryforwards  of  $66.2 million.  Of  that  amount, 
approximately  $55.6 million  of  the  federal  net  operating  loss  is  attributable  to  employee  stock  option  deductions,  the  benefit 
from which will be allocated to additional paid-in capital rather than current earnings if subsequently realized. The federal net 
operating  losses  begin  expiring  in  2026.  The  Company  also  has  federal  research  and  development  credit  carryforwards  of 
approximately  $2.9 million  that  will  begin  to  expire in 2013  if  not utilized  prior to that time.  The Company has net  operating 
losses  in  various states  that  total  $10.2 million. The  state  net  operating  loss carryforwards  expire  in  fiscal  years 2010 through 
2021. In addition, the Company has Canadian non-capital income tax loss carryforwards of $32.4 million, a scientific research 
and  experimental  development  pool  in  Canada  of  $36 million,  and  investment  tax  credits  in  Canada  of  $7.7 million  that  will 
begin  to  expire in  2010  if  not utilized  prior  to  that  time.  The investment  tax credits  are accounted  for under  the flow-through 
method of accounting. Utilization of the net operating losses and tax credits may be subject to substantial annual limitation due 
to the “change in ownership” provisions of the Internal Revenue Code of 1986. The annual limitation may result in the expiration 
of net operating losses and research and development credits before utilization.  

76

                                   
   
 
 
   
   
   
   
   
 
 
   
 
   
   
 
   
   
   
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
  
 
   
   
   
   
   
 
 
   
   
 
   
   
 
   
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
Undistributed earnings of the Company’s foreign subsidiaries are considered permanently reinvested and, accordingly, no 
provision for U.S. federal or state income taxes has been provided thereon. The cumulative amount of undistributed earnings of 
the  Company’s  non-US  subsidiaries  was  approximately  $0.9 million  at  December 31,  2009,  $0  at  December 31,  2008  and 
$6.3 million at December 31, 2007. The ultimate tax liability related to repatriation of the Company’s undistributed earnings is 
not estimable at the present time.  

On January 1, 2007, the Company adopted the provisions of ASC 740 (FIN No. 48). There were no liabilities, interest or 
penalties recorded for uncertain tax positions as a result of the adoption. Under ASC 740, the impact of an uncertain tax position 
that  is  more  likely  than  not  of  being  sustained  upon  audit  by  the  relevant  taxing  authority  must  be  recognized  at  the  largest 
amount that is more likely than not to be sustained. No portion of an uncertain tax position will be recognized if the position has 
less  than  a  50%  likelihood  of  being  sustained.  Also,  under  ASC  740,  interest  expense  is  recognized  on  the  full  amount  of 
deferred benefits for uncertain tax positions.  

As  of  December 31,  2009  and  December 31,  2008,  the  Company  had  recorded  gross  unrecognized  tax  benefits  of 
approximately  $0.8 million  and  $0.3 million,  respectively.  All  of  the  unrecognized  tax  benefits  as  of  December 31,  2009,  if 
recognized,  would  impact  the  effective  tax  rate.  The  Company  recognized  interest  expense  and  penalties  associated  with 
uncertain  tax  positions  as  a  component  of  income  tax  expense.  During  the  years  ended  December 31,  2009  and  2008,  the 
Company recognized approximately $3,000 and $23,000 in tax related interest and penalties, respectively. Reserves for interest 
and penalties  as of  December 31, 2009 and  2008  are  not significant  as the  Company  has  net operating loss  carryovers.  In the 
years ended December 31, 2009 and 2008, cash paid for taxes, net of cash received for tax refunds, was approximately $867,000 
and $405,000, respectively.  

A reconciliation of the beginning and ending balance of unrecognized tax benefits is as follows:  

Balance at December 31, 2007 
Additions based on tax positions related to the current year
Additions for tax positions of prior years
Reductions for tax positions of prior years 
Settlements 
Lapse of statute of limitations 
Cumulative translation adjustment 

Balance at December 31, 2008 
Additions based on tax positions related to the current year
Additions for tax positions of prior years
Reductions for tax positions of prior years 
Settlements 
Lapse of statute of limitations 
Cumulative translation adjustment 

Balance at December 31, 2009 

$

$

$

—
—
251
—
— 
—
—

251 
74
508
—
—
—
—

833

As of December 31, 2009, there were no unrecognized tax benefits that the Company expects would change significantly 

over the next 12 months.  

The  Company  files  U.S.,  state  and  foreign  income  tax  returns  in  jurisdictions  with  varying  statutes  of  limitations.  In  the 
U.S., the federal income tax returns for years after 1996 are open and in Canada, the federal income tax returns for years after 
2003 are open.  There are numerous other income tax jurisdictions for which tax returns are  not yet settled, none of which are 
individually significant. The Company is not currently under audit in any major taxing jurisdictions.  

77

  
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
  
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
  
 
   
 
   
 
 
 
NOTE 11 — LONG-TERM DEBT  

On  December 31,  2009,  long-term  debt  consisted  of  a  loan  payable  to  Technology  Partnership  Canada  (TPC) valued  at 

$3.6 million and the related short term interest payable of $868,000.  

On December 12, 2003, LMD entered into an agreement with the Ministry of Industry of the Government of Canada under 
which the Government agreed to invest up to Canadian (Cdn) $7.3 million relating to the development of several genetic tests. 
This  agreement  was  amended  in  March 2009.  Funds  were  advanced  from  TPC,  a  special  operating  program.  The  actual 
payments  received  by  the  Company  were  predicated  on  eligible  expenditures  made  during  the  amended  project  period  which 
ended  July 31,  2008.  As  of  December 31,  2009,  the  Company had  received  $4.6 million  from  TPC ($4.9  million in  Canadian 
dollars) which is expected  to be repaid along with  approximately  $1.6 million  of  imputed interest for a total of approximately 
$6.2 million ($6.5 million in Canadian dollars). Approximately $761,000 ($799,000 in Canadian dollars) of the interest has been 
repaid as of December 31, 2009.  

LMD agreed to repay the TPC funding through a royalty on revenues. This liability was assumed by the Company as part of 
the acquisition and the liability was recorded at fair value as of the date of acquisition. This liability is subject to adjustments for 
foreign currency translation effects as it is a foreign currency denominated balance. Royalty payments commenced in 2007 at a 
rate of 1% of total revenue and at a rate of 2.5% for 2008 and thereafter. Aggregate royalty repayment will continue until total 
advances  plus  imputed  interest  has  been  repaid  or  until  December 31,  2016,  whichever  is  earlier.  The  repayment  obligation 
expires on December 31, 2016 and any unpaid balance will be cancelled and forgiven on that date. Should the term of repayment 
be shorter than expected  due to higher than expected assay revenue,  the effective interest rate  would increase as repayment is 
accelerated. Repayments denominated in U.S. Dollars are currently projected to be as shown in the table below, but actual future 
sales generating  a  repayment  obligation  will vary  from  this  projection  and  are subject to  the  risks  and  uncertainties described 
elsewhere  in  this  report,  including  under  “Risk  Factors”  and  “Safe  Harbor  Cautionary  Statement.”  Furthermore,  payments 
reflected in U.S. Dollars are subject to adjustment based upon applicable exchange rates as of the reporting date.  

Estimated repayments on the debt for the next five years and thereafter are as follows (in thousands):  

2010 
2011 
2012 
2013 
2014 
Thereafter 

Less: Amount representing implied interest 
Total principal repayments 
Discount 
Total long-term debt 
Less: Current portion of long-term debt

$

$

$
$
$

$

868
947
1,143
1,360 
1,112
—
5,430
(414)
5,016
(557)
4,459
(868)
3,591

In  2009  and  2008,  the  Company  had  imputed  interest  expense  related  to  its  long-term  debt  of  $179,000  and  $221,000, 
respectively recorded in the assay segment. The effective interest rate was 4.03% and 4.88% as of December 31, 2009 and 2008, 
respectively. At December 31, 2009 and 2008, the fair value of the Company’s long-term debt was approximately $4.1 million 
and $3.0 million, respectively. The Company’s long-term debt is classified as a Level 3 instrument and the Company has used a 
discounted cash flow (DCF) model to determine the estimated fair value as of December 31, 2009 and 2008. The assumptions 
used in preparing the DCF model include estimates for (i) the amount and timing of future interest and principal payments and 
(ii) the  rate  of  return  indicative  of  the  investment  risk  in  the  ownership  of  the  TPC  debt.  In  making  these  assumptions,  the 
Company considered relevant factors including the likely timing of principal repayments and the probability of full repayment 
considering the timing of royalty payments based upon total revenue.  

78

                                   
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
  
 
 
 
   
 
 
 
 
 
   
 
   
 
 
 
   
 
 
 
  
 
   
 
 
 
NOTE 12 — NET INCOME (LOSS) PER SHARE  

The  following  table sets forth  the  computation of  basic  and  diluted net  income  (loss) per  share (in thousands,  except per 

share data):  

Numerator: 

Net income (loss) 

Denominator: 

Year Ended December 31,
2008

2007

2009

$

17,729

$

3,057   

$

(2,711)

Denominator for basic net income (loss) per share — weighted average 

common stock outstanding 

Effect of dilutive securities: 
Stock options and awards 

40,562   

37,868   

34,361 

1,071

1,832   

—

Denominator for diluted net income (loss) per share — weighted 

average shares outstanding — diluted 

Basic net income (loss) per share 
Diluted net income (loss) per share 

41,633

39,700   

34,361

$
$

0.44
0.43

$
$

0.08   
0.08   

$
$

(0.08)
(0.08)

Restricted stock awards (RSAs) and stock options to acquire 690,000, 623,000, and 1.1 million shares for the years ended 
December 31, 2009, 2008 and 2007, respectively, were excluded from the computations of diluted earnings per share because the 
effect of including the RSAs and stock options would have been anti-dilutive.  

NOTE 13 — STOCKHOLDERS’ EQUITY AND COMPREHENSIVE INCOME/ LOSS  

Preferred Stock  

The Company’s Board of Directors has the authority to issue up to 5,000,000 shares of preferred stock in one or more series 
and to fix the rights, preferences, privileges and restrictions thereof, including dividend rights, dividend rates, conversion rights, 
voting rights, terms of redemption, redemption prices, liquidation preferences and the number of shares constituting any series or 
the designation of such series, without further vote or action by the Company’s stockholders. At December 31, 2009 and 2008, 
there was no preferred stock issued and outstanding.  

Stockholders’ Rights Plan  

On  June 20,  2001,  the  Company’s  Board  of  Directors  declared  a  dividend  of  one  right  for  each  outstanding  share  of  the 
Company’s common stock to stockholders of record at the close of business on July 2, 2001. Each right entitles the registered 
holder to purchase from the Company a unit consisting of one one-hundredth of a share of Series A Junior Participating Preferred 
Stock,  par  value  $0.001  per  share,  at  a  purchase  price  of  $100  per  fractional  share,  subject  to  adjustment.  The  rights  are  not 
currently  exercisable  and  will  become  exercisable  only  in  the  event  a  person  or  group  acquires  beneficial  ownership  of 
20 percent or more of common stock. The rights expire on June 20, 2011.  

Comprehensive Income/Loss  

The  Company’s  comprehensive  income  or  loss  is  comprised  of  net  income  or  loss  and  foreign  currency  translation  and 
unrealized gains and losses on available-for-sale securities. Comprehensive income for the year ended December 31, 2009 was
approximately $17.8 million and comprehensive income for the year ended December 31, 2008 was approximately $3.0 million. 

79

                                   
   
 
 
   
   
 
 
   
 
   
   
  
 
   
   
 
   
   
 
 
 
 
 
   
   
 
   
 
 
 
 
 
 
 
 
  
 
   
   
 
  
 
   
   
NOTE 14 — EMPLOYEE BENEFIT PLANS AND STOCK-BASED COMPENSATION  

Stock-Based Compensation  

At December 31, 2009, the Company has two stock-based employee compensation plans pursuant to which grants may be 
made:  the  2006  Management  Stock  Purchase  Plan  (the  “MSPP”)  which  was  approved  at  the  Company’s  Annual  Meeting  on 
May 25, 2006 and the Amended and Restated 2006 Equity Incentive Plan (the “Equity Incentive Plan”) which was approved at 
the Company’s Annual Meeting on May 25, 2006 and amended at the Company’s Annual Meeting on May 21, 2009. No further 
grants shall be made pursuant to the 2000 Long-Term Incentive Plan (the “2000 Plan”), the 2001 Broad-Based Stock Option Plan 
(the  “2001  Plan”),  or  the  Tm  Bioscience  Corporation  Share  Option  Plan  (the  “Tm  Plan”)  that  the  Company  assumed  in 
connection with the Tm acquisition. The Tm Plan governs the former Tm options which were exchanged for options to purchase 
shares of Luminex common stock in connection with the acquisition.  

Equity Incentive Plans  

Under the Company’s Equity Incentive Plan, 2000 Plan, 2001 Plan, and the Tm Plan, certain employees, consultants and 
non-employee directors have been granted RSAs, restricted share units (RSUs) and options to purchase shares of common stock. 
The options, RSAs, and RSUs generally vest in installments over a four to five year period, and the options expire either five or 
ten  years  after  the  date  of  grant.  Under  the  Equity  Incentive  Plan,  certain  employees,  directors  of,  and  consultants  to  the 
Company are eligible to be granted RSAs, RSUs, and options to purchase common stock. The MSPP provides for the granting of 
rights  to defer  an  elected  percentage  of  their  bonus  compensation through  the  purchase of  restricted  shares  of  the  Company’s 
common stock, discounted by 20%, to certain officers of the Company. As of December 31, 2009, there were approximately 2.7 
million  shares  authorized  for  future  issuance  under  the  Company’s  Equity  Incentive  Plan  and  500,000  shares  eligible  for 
purchase, pursuant to the terms and conditions thereof, under the MSPP.  

The Equity Incentive Plan, the MSPP, the 2000 Plan, the 2001 Plan, and the Tm Plan are administered by the Compensation 
Committee  of  the  Board  of  Directors.  The  Compensation  Committee  has  the  authority  to  determine  the  terms  and  conditions 
under which awards will be granted from the Equity Incentive Plan, including the number of shares, vesting schedule and term, 
as applicable. Any option award exercise prices, as set forth in the Equity Incentive Plan, will be equal to the fair market value 
on the date of grant. Under certain circumstances, the Company may repurchase previously granted RSAs and RSUs.  

On  March 25,  2007,  the  Compensation  Committee  approved  an  amendment  to  the  restricted  stock  agreement,  dated 
May 17, 2004 (the “Restricted Stock Agreement”), of the Company’s CEO, Patrick J. Balthrop. The Company and Mr. Balthrop 
initially entered into the  Restricted Stock Agreement in connection with  the hiring  of  Mr. Balthrop as the  President and  Chief 
Executive Officer of the Company. The Restricted Stock Agreement provided for the grant of 200,000 restricted shares, which 
would  vest  in  portions  based  on  the  attainment  of  certain  performance  goals  related  to  Company  revenue,  earnings  and  stock 
price. If the goals provided for in the Restricted Stock Agreement were not achieved by the end of the fifth anniversary of the 
date  of  the  Restricted  Stock  Agreement,  all  non-vested  shares  would  be  forfeited.  The amendment  provides  for  the  automatic
vesting of all unvested restricted shares immediately prior to the fifth anniversary of the date of the Restricted Stock Agreement, 
to the extent any or all of the performance measures have not been previously achieved. Mr. Balthrop’s 200,000 share restricted 
stock award, as amended, has market, service or performance criteria for vesting of all shares. The Company has assumed that 
vesting  will  occur  at  the  end  of  the  five  years  based  on  achievement  of  the  service  criteria  so  all  expense  is  being  amortized 
straight-line over the five-year period from May 17, 2004 through 2009. Pursuant to the amendment to this award, the award was 
revalued  to  the  market  price  on  the  date  of  amendment  of  $14.39.  This  resulted  in  additional  expense  to  the  Company  of 
approximately $356,000 of which approximately $29,000 and $70,000 was recognized in 2009 and 2008, respectively.  

80

                                   
   
On  December 4, 2008 and March 11,  2009  the Board  adopted the  Luminex  Corporation  2008  Long Term  Incentive  Plan 
(the “2008 LTIP”) and the Luminex Corporation 2009 Long Term Incentive Plan (the “2009 LTIP”), respectively. Awards under 
the  2008  LTIP  and 2009 LTIP  were granted  by the  Board in the  form of  RSUs  and are  to  be  treated  as  Performance Awards 
under the Equity Incentive Plan. Grants of RSUs under the 2008 LTIP and 2009 LTIP shall initially be unvested and represent 
the  maximum amount  of shares  that  participants  may  receive  under  the plan,  assuming  achievement  of the maximum  level of 
performance goals established for the grant, and subject to adjustment for certain transactions and other non-recurring events that 
may affect Luminex or its financial performance. On December 4, 2008, the Company’s Chief Executive Officer was granted an 
unvested RSU under the 2008 LTIP for 102,564 shares of Luminex Common Stock, and the Company’s then Chief Operating 
Officer was granted an unvested RSU under the 2008 LTIP for 76,923 shares of Luminex Common Stock. Partial or complete 
vesting  of  the  RSUs  shall  be  dependent  upon  the  continued  employment  and  the  achievement  of  certain  performance  goals 
during the performance period extending from the date of grant through December 31, 2010. The Company’s Chief Operating 
Officer forfeited his entire grant upon his resignation on February 1, 2009. On March 11, 2009, the Company’s Chief Executive 
Officer was granted an award for an unvested RSU under the 2009 LTIP for $2,200,000 worth of shares of Luminex Common 
Stock, and the Company’s Chief Financial Officer was granted an award for an unvested RSU under the 2009 LTIP for $825,000 
worth of shares of Luminex Common Stock. The actual maximum number of shares of 140,395 shares and 52,648 shares for the 
CEO  and  CFO,  respectively,  was  determined  on  May 12,  2009,  based  upon  the  closing  price  of  the  stock  on  that  date. 
Performance goals under the grants are based on the following components, with the following weights given to each: 50% on 
the trading price of Luminex Common Stock at the end of the performance period and 50% on Luminex’s operating cash flows 
per diluted share at the end of the performance period.  

The 2008 LTIP performance goals are as described below:  

•

•

  Partial or complete achievement of the trading  price goal is dependent upon the average closing price of Luminex’s 
Common  Stock  for  the  twenty  consecutive  trading  days  ending  December 31,  2010,  inclusive,  subject  to  certain
adjustments as described in the 2008 LTIP. There is a range of trading price targets as follows: a minimum threshold
of $24.79 per share, a target of $28.17 per share, and a maximum goal of $44.73 per share. 

  Partial  or  complete  achievement  of  the  operating  cash  flow  goal  is  dependent  upon  the  average  quarterly  “total 
operating  cash  flows”  per  diluted  share  for  the  four  quarters  ended  December 31,  2010,  as  further  described  in  the
2008 LTIP. “Total operating cash flows” means Luminex’s GAAP net cash provided by operating activities as shown 
on its financial statements for the 12 month period ended December 31, 2010, as further described in the 2008 LTIP.
There is a range of targets as follows: a minimum threshold of $0.101 per share, a target of $0.111 per share, and a
maximum goal of $0.157 per share. 

The 2009 LTIP performance goals are as described below:  

•

•

  Partial or complete achievement of the trading  price goal is dependent upon the average closing price of Luminex’s 
Common  Stock  for  the  twenty  consecutive  trading  days  ending  December 31,  2011,  inclusive,  subject  to  certain
adjustments as described in the 2009 LTIP. There is a range of trading price targets as follows: a minimum threshold
of $32.38 per share, a target of $36.79 per share, and a maximum goal of $58.42 per share. 

  Partial  or  complete  achievement  of  the  operating  cash  flow  goal  is  dependent  upon  the  average  quarterly  “total 
operating  cash  flows”  per  diluted  share  for  the  four  quarters  ended  December 31,  2011,  as  further  described  in  the
2009 LTIP. “Total operating cash flows” means Luminex’s GAAP net cash provided by operating activities as shown 
on its financial statements for the 12 month period ended December 31, 2011, as further described in the 2009 LTIP.
There is a range of targets as follows: a minimum threshold of $0.134 per share, a target of $0.152 per share, and a
maximum goal of $0.241 per share. 

81

                                   
   
 
 
 
 
In the event that a participant achieves less than the maximum level of the performance goals, the total number of shares 
represented  by  such  RSU  shall  be  reduced  to  reflect  where  actual  performance  lies  in  the  range  of  performance  goals  and 
weighted  aggregate  corresponding  payout  opportunities  established  for the  grant.  Calculation  of shares between  threshold  and 
maximum performance shall be determined based on straight-line interpolation.  

Accounting for Stock Compensation  

Stock-based  compensation  costs  are  generally  based  on  the  fair  value  calculated  from  the  Black-Scholes  option-pricing 
model  on  the  date  of  grant  for  stock  options  and  market  value  on  the  date  of  grant  for  RSAs.  The  fair  values  of  stock  are 
amortized as compensation expense on a straight-line basis over the vesting period of the grants.  

In accordance with ASC 718 Company evaluates the assumptions used in the Black-Scholes model at each grant date using 
a consistent methodology for computing expected volatility, expected term and risk-free rate of return. Calculation of expected 
volatility is based on historical volatility. The expected term is calculated using the contractual term of the options as well as an 
analysis of the Company’s historical exercises of stock options. The estimate of the risk-free rate is based on the U.S. Treasury 
yield curve in effect at the time of grant. The Company has never paid cash dividends and does not currently intend to pay cash 
dividends, and thus has assumed a 0% dividend yield. The assumptions used are summarized in the following table:  

Dividend yield 
Expected volatility 
Risk-free rate of return 
Expected life 
Weighted average fair value at grant date

[1]

  No stock options were issued to employees during this period. 

2009

2008

2007

0.0%
0.6
2.0% 

7 yrs
8.63

$

0.0% 
0.5 
3.0% 

8 yrs 
8.62 

$

0.0%
0.5
5.0%

7 yrs
4.70[1]

$

As part of the requirements of ASC 718, the Company is required to estimate potential forfeitures of stock grants and adjust 
compensation  cost  recorded  accordingly.  The  estimate  of  forfeitures  is  based  on  historical  forfeiture  performance  and  will  be 
adjusted over the requisite service period to the extent that actual forfeitures differ, or are expected to differ, from such estimates. 
Changes in estimated forfeitures  will  be  recognized  through  a  cumulative catch-up  adjustment  in  the period of evaluation and 
will also impact the amount of stock compensation expense to be recognized in future periods.  

82

                                   
   
 
 
 
   
 
 
 
  
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
The Company’s stock option activity for the years ended December 31, 2007, 2008 and 2009 is as follows:  

Stock Options
Outstanding at December 31, 2006 
Granted 
Exercised 
Cancelled or expired 
Outstanding at December 31, 2007 
Granted 
Exercised 
Cancelled or expired 
Outstanding at December 31, 2008 
Granted 
Exercised 
Cancelled or expired 
Outstanding at December 31, 2009 

Vested at December 31, 2009 and expected to vest 

Exercisable at December 31, 2009 

    Weighted    

Shares
(in thousands)
3,163
823
(332) 
(210)
3,444
77
(644) 
(106)
2,771
167
(72)
(70) 

2,796

2,794

2,558

$

$

$

$

$

$

Average
Exercise
Price

9.76
20.91

5.63   

23.86
11.96
20.70
10.99   
24.22
11.96
16.31
7.90
17.80   
12.18

12.17

11.72

Weighted   
Average   
Remaining   
Contractual  
Life

Aggregate
Intrinsic
Value
(in thousands)

3.62  

3.62  

3.15  

$

$

$

12,994

12,994

12,972

During  the  years  ended  December 31,  2009,  2008  and  2007,  the  total  intrinsic  value  of  stock  options  exercised  was 
$0.6 million, $6.7 million and  $3.2 million, respectively, and  the  total fair value of stock options that vested  was $1.0 million, 
$3.2 million and $2.8 million, respectively. The Company had $1.6 million of total unrecognized compensation costs related to 
stock options at December 31, 2009 that are expected to be recognized over a weighted-average period of 2.2 years.  

83

                                   
   
 
 
  
   
 
 
 
 
   
 
 
 
 
 
 
  
 
  
   
 
  
   
 
 
 
   
  
   
 
 
  
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
   
 
  
   
 
 
 
   
  
   
 
 
  
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
   
 
  
   
 
  
   
 
 
 
   
  
   
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
  
   
 
  
 
   
   
   
   
   
  
   
 
 
The Company’s restricted share activity for the year ended December 31, 2009 is as follows:  

Restricted Stock Awards
Non-vested at December 31, 2008 
Granted 
Vested 
Cancelled or expired 
Non-vested at December 31, 2009 

Restricted Stock Units
Non-vested at December 31, 2008 
Granted 
Vested 
Cancelled or expired 
Non-vested at December 31, 2009 

    Weighted-
Average  
    Grant-Date
Fair Value
15.39
$
16.16
14.78
16.11 
15.90

$

Shares
(in thousands)   
1,197   
485   
(464) 
(117) 
1,101   

Shares
(in thousands)
280
354
(12)
(77)
545

As of December 31, 2009, there was $22.1 million of unrecognized compensation cost related to RSAs and RSUs. That cost 
is expected to be recognized over a weighted average-period of 3.1 years. The total fair value of restricted shares vested during 
the year ended December 31, 2009, 2008 and 2007 was $7.1 million, $4.4 million, and $2.8 million, respectively.  

RSAs and RSUs may be granted at the discretion of the Board of Directors under the Equity Incentive Plan in connection 
with the hiring or retention of key employees and are subject to certain conditions. Restrictions expire at certain dates after the 
grant  date  in  accordance with  specific provisions  in  the  applicable  agreement.  During  the  year  ended December 31,  2009,  the 
Company awarded 485,048 shares of restricted stock awards, which had a fair value at the date of grant ranging from $14.30 —
$21.42. During the year ended December 31, 2008, the Company awarded 310,096 shares of restricted stock awards, which had 
a  fair  value  at  the  date  of  grant  ranging  from  $16.12  —  $24.69.  During  the  year  ended  December 31,  2007,  the  Company 
awarded 776,359 shares of restricted common stock, which had a fair value at the date of grant ranging from $12.43 — $14.39. 
During the year ended December 31, 2009, the Company awarded 354,157 shares of restricted stock units, which had a fair value 
at the date of grant ranging from $15.51 — $18.48. During the year ended December 31, 2008, the Company awarded 283,828 
shares of restricted stock units, which had a fair value at the date of grant ranging from $16.12 — $24.21. No restricted stock 
units  were  awarded  in  2007.  Compensation  under  these  restricted  stock  awards  and  units  was  charged  to  expense  over  the 
restriction period and amounted to $7.4 million, $6.1 million, and $4.4 million in 2009, 2008 and 2007, respectively.  

There were no significant stock compensation costs capitalized into assets as of December 31, 2009.  

The Company received $0.6 million, $7.1 million, and $1.9 million for the exercise of stock options during the years ended 
December 31,  2009, 2008 and 2007,  respectively. Cash was  not  used  to  settle  any  equity instruments  previously granted. The 
Company issued shares pursuant to grants relating to each of the Equity Incentive Plan, 2000 Plan and 2001 Plan from reserves 
upon the exercise of stock options and vesting of RSAs. The Company does not currently expect to repurchase shares from any 
source to satisfy such obligation under these plans.  

84

                                   
   
 
   
   
 
 
 
   
   
 
 
 
 
 
 
   
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
The following are the stock-based compensation costs recognized in the Company’s consolidated statements of income (in 

thousands):  

Cost of revenue 
Research and development 
Selling, general and administrative 
Stock-based compensation costs reflected in net income (loss)

Reserved Shares of Common Stock  

Year Ended December 31,
2008

2007

2009

$

$

710
1,368
6,082
8,160

$

$

523   
1,143   
5,585   
7,251   

$

$

380
810
5,403
6,593

At  December 31,  2009  and  2008,  the  Company  had  reserved  6,535,475  and  3,873,472  shares  of  common  stock, 
respectively,  for  the  issuance  of  common  stock  upon  the  exercise  of  options,  issuance  of  RSAs,  RSUs,  purchase  of  common 
stock  pursuant to the  MSPP  or other awards  issued  pursuant  to  the Company’s equity  plans  and arrangements.  The following 
table summarizes the reserved shares by plan as of December 31, 2009:  

2000 Plan 
2001 Plan 
2006 Equity Incentive Plan 
2006 Management Stock Purchase Plan
Tm Plan 
Other * 

*

  Balthrop Option and Tm Warrants

Employee Savings Plans  

Options / Warrants
Outstanding

Shares Available   Total Shares

for Future Issuance   Reserved

1,208,300
462,638
839,534   

—
61,161
769,422
3,341,055   

—   
—   
2,695,420   
500,000   
—   
—   
3,195,420   

1,208,300
462,638
3,534,954 
500,000
61,161
769,422
6,536,475 

Effective  January 1,  2001,  the Company  began sponsoring  a retirement plan  authorized  by  section  401(k)  of the  Internal 
Revenue Code. In accordance with the  401(k) plan, all employees are eligible to participate  in the plan on the first day of the 
month  following  the  commencement  of  full  time  employment.  For  2009,  2008,  and  2007,  each  employee  could  contribute  a 
percentage  of  compensation  up  to  a  maximum  of  $16,500,  $15,500,  and  $15,500  per  year,  respectively,  with  the  Company 
matching  50%  of  each  employee’s  contributions.  The  Company’s  contributions  for  2009,  2008  and  2007  were  $767,000, 
$536,000, and $543,000, respectively.  

85

                                   
   
 
 
   
   
 
 
   
 
 
   
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
     
 
 
  
   
 
 
 
 
 
 
 
 
  
  
   
 
 
 
 
 
 
 
 
 
 
 
NOTE 15 — COMMITMENTS AND CONTINGENCIES  

Lease Arrangements  

The Company has operating leases related primarily to its office and manufacturing facilities with original lease periods up 
to  10 years.  Rental  and  lease  expense  for  these  operating  leases  for  the  years  2009,  2008  and  2007  totaled  approximately 
$2.6 million, $2.6 million, and $1.2 million, respectively.  

Minimum annual lease commitments as of December 31, 2009 under non-cancelable leases for each of the next five years 

and in the aggregate were as follows (in thousands):  

2010 
2011 
2012 
2013 
2014 
Thereafter 
Total 

$

$

2,446
2,414
2,242
2,131 
1,670
518
11,421

These  non-cancelable  lease  commitments  related  to  facilities  include  certain  rent  escalation  provisions  which  have  been 
included  in  the  minimum  annual  rental  commitments  shown  above.  These  amounts  are  recorded  to  expense  on  a  straight-line 
basis over the life of the lease. In addition, some of the Company’s leases contain options to renew the lease for five to ten years 
at  the  then  prevailing  market  rental  rate,  right  of  first  refusal  to  lease  additional  space  that  becomes  available,  or  leasehold 
improvement incentives.  

Non-Cancelable Purchase Commitments  

As  of  December 31,  2009  the  Company  had  approximately  $12.7 million  in  purchase  commitments  with  several  of  its 

inventory suppliers. These commitments require delivery of minimum amounts of components throughout 2017.  

Employment Contracts  

The  Company  has  entered into  employment  contracts  with  certain  of its  key executives. Generally,  certain  amounts  may 
become  payable  in  the  event  the  Company  terminates  the  executives’  employment  without  cause  or  the  executive  resigns  for 
good reason.  

Gain on Settlement of Liability  

In 2007, the Company renegotiated a contract acquired as part of the acquisition of Tm Bioscience. As part of the contract 
renegotiation  there was  a  settlement of a liability of $2.3  million which  the Company has recorded  as  a  gain  on  settlement of 
liability in 2007.  

86

                                   
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
   
 
 
 
Legal Proceedings  

On  July 24,  2009,  Luminex  notified  Abbott  Molecular  Inc.  of  the  Company’s  intent  to  convert  its  right  to  distribute 
Luminex’s  xTAG®  Respiratory  Viral  Panel  from  exclusive  to  non-exclusive  on  a  worldwide  basis  under  the  Distribution 
Agreement,  dated  February 1,  2008,  between  Abbott  Molecular  and  LMD.  On  September 11,  2009,  Abbott  Molecular  Inc. 
notified  the  Company  that  it  intended  to  exercise  its  right  to  seek  arbitration under  the  Distribution  Agreement.  Among other 
matters,  Abbott  disputed  LMD’s  right  to  terminate  Abbott’s  exclusive  right  to  distribute  RVP  under  the  Agreement.  The 
arbitration to resolve this matter was held on December 14-15, 2009. The arbitrator issued his binding ruling on December 30, 
2009,  instructing  Luminex, among other  matters, to reinstate Abbott’s exclusive right  to  distribute  RVP outside of  the United 
States  and  co-exclusively  with  Fisher  Scientific  within  the  United  States.  All  other  terms  and  conditions  of  the  Distribution
Agreement remain in effect and are unaffected by the Arbitration.  

On  June 19,  2009,  Luminex  terminated  a  long-term  supply  contract  related  to  its  FlexmiR®  product  line.  A  payment  of 

$1 million was made in June 2009 related to this termination. This payment included a purchase of $220,000 of inventory.  

NOTE 16 — GUARANTEES  

The  terms  and  conditions  of  the  Company’s  development  and  supply  and  license  agreements  with  its  strategic  partners 
generally  provide  for  a  limited  indemnification  of  such  partners,  arising  from  the  sale  of  Luminex  systems  and  consumables, 
against  losses,  expenses  and  liabilities  resulting  from  third-party  claims  based  on  an  alleged  infringement  on  an  intellectual 
property right of such third party.  The terms of such indemnification provisions  generally limit the  scope  of and  remedies for 
such  indemnification  obligations.  To  date,  the  Company  has  not  had  to  reimburse  any  of  its  strategic  partners  for  any  losses 
arising from such indemnification obligations.  

NOTE 17 — SEGMENT AND GEOGRAPHIC INFORMATION  

The  Chief Operating  Decision Maker  (CODM) is Luminex’s Chief  Executive  Officer. The  CODM allocates  resources  to 
and assesses the performance of each operating segment using information about its  revenue and  projections.  The Company’s 
reporting  segments  reflect  the  nature  of  the  products  offered  to  customers  and  the  markets  served  and  are  comprised  of  the 
following:  

Technology segment  —  represents  the Company’s base  business and  consists of system sales  to  partners,  raw bead sales, 

royalties, service and support of the technology, and other miscellaneous items.  

Assay segment  — consists  of LBG  and LMD and is primarily  involved in  the development  and sale  of  assays  on  xMAP 

technology for use on Luminex’s installed base of systems.  

Intersegment sales are recorded at fixed prices which approximate the prices charged to third party strategic partners and 
are  not  a  measure  of  segment  operating  earnings.  Intersegment  sales  of  approximately  $14.0 million,  $6.5 million,  and 
$3.5 million for the years ended December 31, 2009, 2008, and 2007 have been eliminated upon consolidation, respectively.  

87

                                   
   
Following is selected information for the years ended December 31, 2009 and 2008 or as of December 31, 2009 and 2008

(in thousands):  

  Technology  
Segment

2009
Assay

Technology  
Segment

2008
Assay   

   Segment

Consolidated

  Segment   Consolidated

Revenues from external customers   

$

87,389  

$ 33,254

$

120,643

$

83,567  

$ 20,880   $

104,447

Depreciation and amortization 

4,428  

3,901

Segment profit (loss) 

21,406  

(3,677)

8,329

17,729

3,279  

3,722  

9,405  

(6,348) 

7,001

3,057

Segment assets 

170,927  

  77,086

248,013

145,008  

  72,283  

217,291

The  table  below  provides  information  regarding  long-term  assets  and  product  revenues  from  the  Company’s  sales  to 

customers within the United States and in foreign countries for the years ended December 31 (in thousands):  

Domestic 
Foreign: 

Europe 
Asia 
Canada 
Other 

Sales to Customers
2008

2009

2007

2009

Long-Term Assets
2008

2007

$ 97,842   

$ 89,465

$ 63,591

$ 50,045

$ 13,553 

$ 10,863

11,398   
4,337   
4,608   
2,458   
$ 120,643   

9,279
1,204   
2,204
2,295
$ 104,447

7,835

739   
846
1,999
$ 75,010

1,078
264 
54,446[1]
24
$ 105,857

428 
— 

501
— 

  56,885[1] 

  58,676[1]

32 
$ 70,898 

—
$ 70,040

[1]   $39,617 of the long-term assets in Canada represents goodwill from the acquisition of LMD.

Our aggregate foreign currency transaction losses of $214,000 and $465,000 were included in determining our consolidated

results for the year ended December 31, 2009 and 2008, respectively.  

88

                                   
   
 
 
  
   
 
   
  
   
 
 
 
 
 
  
 
  
   
 
   
  
   
  
 
   
  
   
  
   
  
   
  
   
  
   
 
 
 
 
 
  
 
  
   
 
   
  
   
 
 
 
 
  
 
  
   
 
   
  
   
 
 
 
 
   
   
   
 
 
   
 
 
   
 
 
 
   
 
 
  
 
   
   
   
 
 
   
 
 
 
   
   
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
NOTE 18 — SETTLEMENT OF LITIGATION  

On January 16, 2008, Luminex Corporation and LMD were served with a complaint, filed by The Research Foundation of 
the  State  University  of  New  York  (SUNY) in  Federal  District  Court  for  the  Northern  District  of  New  York,  alleging,  among 
other  claims,  that  LMD  breached  its  license  agreement  with  SUNY  by  failing  to  pay  royalties  allegedly  owed  under  the 
agreement. The complaint sought an undetermined amount of damages as well as injunctive relief. On March 27, 2009, Luminex 
and  LMD  settled  the  pending  litigation  with  SUNY.  As  part  of  the  settlement,  SUNY  received  a  one  time  cash  payment  of 
approximately  $4.4 million,  which  represents  all  amounts  owed  by  Luminex  as  part  of the  settlement.  The  cash  payment  was 
made  by  Luminex  in  exchange  for  resolution  of  the  dispute  between  the  companies  and  a  complete  release  of  all  claims  by 
SUNY against Luminex and correspondingly a complete release of all claims by Luminex against SUNY. All other terms of the 
agreement are confidential. The parties have formally dismissed the lawsuit, as required by the applicable settlement agreement.  

The  Company  settled its  pending  litigation  with  Rules Based  Medicine, Inc.  (RBM) on  October  15,  2007.  As  part  of  the 
settlement, Luminex received a cash payment of $12.5 million in 2007. The cash payment was made by RBM in exchange for 
resolution of the dispute between the companies regarding Biophysical Corporation as well as the retirement of Luminex’s stock 
ownership  in  RBM  and  the  grant  of  certain  additional  licensing  rights  from  Luminex.  All  other  terms  of  the  agreement  are 
confidential.  The  parties  formally  dismissed  the  lawsuit  on  October 24,  2007,  as  required  by  the  settlement  agreement.  The 
Company recorded $11.5 million of the $12.5 million payment in the fourth quarter of 2007 as a gain on settlement of litigation. 
The remaining $1.0 million has been deferred related to the license agreement with RBM and will be recognized over the term of 
the license agreement.  

NOTE 19 — RECENT ACCOUNTING PRONOUNCEMENTS  

The  FASB  recently  amended  its  guidance  on  the  information  that  a  reporting  entity  must  provide  in  its  financial  reports 
about a transfer of financial assets; the effects of a transfer on its financial position, financial performance, and cash flows; and a 
transferor’s continuing involvement in transferred financial assets. Specifically, among other aspects, the new guidance amends 
previous  guidance  related  to  the  concept  of  a  qualifying  special-purpose  entity,  variable  interest  entities  that  are  qualifying 
special-purpose  entities  and  the  financial-components  approach.  The  new  guidance  is  effective  for  transfer  of  financial  assets 
occurring on or after January 1, 2010. The Company has not  determined the effect that the adoption of the new  guidance will 
have on its financial position or results of operations but the effect will generally be limited to future transactions. Historically, 
the  Company  has  not  had  any  material  transfers  of  financial  assets.  Additionally,  the  FASB  recently  amended  its  guidance 
surrounding a company’s analysis to determine whether its variable interest or interests give it a controlling financial interest in a 
variable interest entity. The primary beneficiary of a variable interest entity is the enterprise that has both (1) the power to direct 
the activities of a variable interest entity that most significantly impact the entity’s economic performance and (2) the obligation 
to absorb  losses of the  entity  that  could  potentially  be significant  to  the  variable  interest  entity  or the right  to receive benefits 
from  the  entity  that  could  potentially  be  significant  to  the  variable  interest  entity.  This  new  guidance  also  requires  ongoing 
reassessments of whether an enterprise is the primary beneficiary of a variable interest entity. The guidance is effective for all 
variable interest entities and relationships with variable interest entities existing as of January 1, 2010. The Company does not 
expect the adoption of this standard to have an impact on its financial position or results of operations.  

89  

                                   
   
In October 2009, the FASB updated its revenue recognition guidance, amending the criteria for separating consideration in 
multiple-deliverable  arrangements.  The  amendments  establish  a  selling  price  hierarchy  for  determining  the  selling  price  of  a 
deliverable. The selling price used for  each deliverable will be based on vendor-specific objective evidence if  available, third-
party  evidence  if  vendor-specific  objective  evidence  is  not  available,  or  estimated  selling  price  if  neither  vendor-specific 
objective evidence  nor third-party evidence is available. The amendments will eliminate the residual method of allocation  and 
require  that  arrangement  consideration  be  allocated  at  the  inception  of  the  arrangement  to  all  deliverables  using  the  relative 
selling  price  method.  The  relative  selling  price  method  allocates  any  discount  in  the  arrangement  proportionally  to  each 
deliverable on the basis of each deliverable’s selling price. This update will be effective prospectively for revenue arrangements 
entered  into  or  materially  modified  in  fiscal  years  beginning  on  or  after  June 15,  2010.  Early  adoption  is  permitted.  The 
Company  is  currently  evaluating  the  requirements  of  this  update  and  has  not  yet  determined  the  impact  on  the  Company’s 
consolidated financial statements.  

In October 2009, the FASB updated its software guidance, changing the accounting model for revenue arrangements that 
include  both  tangible  products  and  software  elements.  Tangible  products  containing  software  components  and  non-software 
components that function together to deliver the tangible product’s essential functionality are no longer within the scope of the 
software  revenue  guidance.  In  addition,  the  amendments  require  that  hardware  components  of  a  tangible  product  containing 
software  components  always  be  excluded  from the  software  revenue guidance.  This update  will be effective prospectively for 
revenue arrangements entered into or materially modified in fiscal years beginning on or after June 15, 2010. Early adoption is 
permitted. The Company is  currently evaluating the requirements of this update and  has  not yet  determined the impact on the 
Company’s consolidated financial statements.  

In January 2010, the FASB updated it guidance related to fair value measurements and disclosures. This guidance requires 
some  new  disclosures  and  clarifies  some  existing  disclosure  requirements  about  fair  value  measurement  in  order  to  improve 
these disclosures and, thus, increase the transparency in financial reporting. Specifically, guidance will require a reporting entity 
to disclose separately the amounts of significant transfers in and out of Level 1 and Level 2 fair value measurements and describe 
the  reasons  for  the  transfers  and  present  separately  information  about  purchases,  sales,  issuances,  and  settlements  in  the 
reconciliation for fair value measurements using significant unobservable inputs. In addition, the FASB clarified the disclosure 
requirements related to the use of  judgment in determining the appropriate classes  of  assets and liabilities when reporting fair 
value measurement for each class and about the valuation techniques and inputs used to measure fair value for both recurring and 
nonrecurring  fair  value  measurements.  The  update  is  effective  for  interim  and  annual  reporting  periods  beginning  after 
December 15, 2009, except for the disclosures about purchases, sales, issuances, and settlements in the roll forward of activity in 
Level  3  fair  value  measurements.  Those  disclosures  are  effective  for  fiscal  years  beginning  after  December 15,  2010,  and  for 
interim periods within those fiscal years. Early application is permitted. The Company is currently evaluating the requirements of 
this update and has not yet determined the impact on the Company’s consolidated financial statements.  

90

                                   
   
SELECTED QUARTERLY RESULTS (UNAUDITED)  

The following table sets forth certain quarterly financial data for the periods indicated (in thousands, except per share data): 

Revenue 
Gross profit 
Income (loss) from operations 
Net income (loss) 
Basic income (loss) per share 
Diluted income (loss) per share 

Revenue 
Gross profit 
Income (loss) from operations 
Net income (loss) 
Basic income (loss) per share 
Diluted income (loss) per share 

  March 31,

2009

June 30,
2009

September 30,    December 31,

2009

2009

Quarter Ended

$

$

$

25,557
17,568
1,584
(2,790)
(0.07)
(0.07) 

  March 31,

2008

$

23,012
15,257
(1,268)
(1,166) 
(0.03)
(0.03)

$

27,801
19,300
1,029
1,112
0.03
0.03   

$

29,118   
18,771   
(512) 
(609) 
(0.01) 
(0.01) 

38,167
25,655
5,298
20,016
0.49
0.48 

Quarter Ended

June 30,
2008

September 30,    December 31,

2008

2008

$

24,341
16,563
(514)
(959) 
(0.03)
(0.03)

$

28,897   
19,554   
2,981   
3,173   
0.08   
0.08   

28,197
19,572
2,154
2,009 
0.05
0.05

ITEM 9.   CHANGES  IN  AND  DISAGREEMENTS  WITH  ACCOUNTANTS  ON  ACCOUNTING  AND  FINANCIAL

DISCLOSURE 

None.  

ITEM 9A. CONTROLS AND PROCEDURES  

Evaluation of Disclosure Controls and Procedures  

We maintain disclosure controls and procedures, as defined in Rule 13a-15(e) promulgated under the Securities Exchange 
Act of 1934 (Exchange Act), which are designed to ensure that information required to be disclosed by us in the reports that we 
file or submit under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the 
Securities  and  Exchange  Commission’s  rules  and  forms  and  that  such  information  is  accumulated  and  communicated  to  the 
Company’s management, including the Company’s Chief Executive Officer and Chief Financial Officer, as appropriate, to allow 
timely decisions regarding required disclosure. We carried out an evaluation, under the supervision and with the participation of 
the Company’s management, including the Company’s Chief Executive Officer and Chief Financial Officer, of the effectiveness 
of  the  design  and  operation  of  the  Company’s  disclosure  controls  and  procedure  as  of  the  end  of  the  period  covered  by  this 
report. Based on the evaluation and criteria of these disclosure controls and procedures, the Chief Executive Officer and Chief 
Financial Officer concluded that the Company’s disclosure controls and procedures were effective.  

91

                                   
   
 
 
   
   
 
 
 
 
 
   
  
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
   
  
 
   
   
   
   
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Management’s Report on Internal Control Over Financial Reporting  

Our management is responsible for establishing and maintaining adequate internal control over financial reporting, as such 
term  is  defined  in  Exchange  Act  Rules 13a-15(f)  and  15d-15(f).  Under  the  supervision  and  with  the  participation  of  our 
management, including our Chief Executive Officer and Chief Financial Officer, we conducted an evaluation of the effectiveness 
of our internal control over financial reporting as of December 31, 2009 based on the framework in Internal Control—Integrated 
Framework  issued  by  the  Committee  of  Sponsoring  Organizations  of  the  Treadway  Commission  (COSO).  Based  on  that 
evaluation, our management concluded that our internal control over financial reporting was effective as of December 31, 2009. 
Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Projections 
of  any  evaluation  of  effectiveness  to  future  periods  are  subject  to  the  risks  that  controls  may  become  inadequate  because  of 
changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.  

Our  independent  registered  public  accounting  firm,  Ernst  &  Young  LLP,  has  issued  a  report  on  their  assessment  of  the 

effectiveness of our internal control over financial reporting, which is provided at Item 8, page 57.  

Changes in Internal Control Over Financial Reporting  

There were no changes in our internal control over financial reporting identified in connection with the evaluation required 
by  Exchange  Act  Rule 13a-15(d)  during  the  fourth  quarter  of  2009  that  have  materially  affected,  or  are  reasonably  likely  to 
materially affect, our internal control over financial reporting.  

ITEM 9B. OTHER INFORMATION  

None.  

PART III  

ITEM 10. DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE  

The  information  required  by  this  Item  concerning  our  directors,  audit  committee,  and  audit  committee  financial  experts, 
code  of  ethics  and  compliance  with  Section  16(a)  of  the  Exchange  Act  is  incorporated  by  reference  to  information  under  the 
captions  “Proposal  1  —  Election  of  Class I  Directors”,  “Corporate  Governance”  and  “Section 16(a)  Beneficial  Ownership 
Reporting  Compliance”  in  our  definitive  proxy  statement for our  2010  annual meeting  of stockholders  to  be  held  on or  about 
May 20,  2010  (Proxy  Statement).  It  is  anticipated  that  our  Proxy  Statement  will  be  filed  with  the  Securities  and  Exchange 
Commission on or about April 7, 2010.  

Pursuant to General Instruction G(3), certain information with respect to our executive officers is set forth under the caption 

“Executive Officers of the Registrant” in Item 4 of this Annual Report on Form 10-K.  

ITEM 11. EXECUTIVE COMPENSATION  

Information required by this  item is  incorporated  by  reference to  the sections  of  the Proxy Statement entitled  “Executive 

and Director Compensation.”  

ITEM 12.   SECURITY  OWNERSHIP  OF  CERTAIN  BENEFICIAL  OWNERS  AND  MANAGEMENT  AND  RELATED

STOCKHOLDER MATTERS 

Information  required  by  this  Item  is  incorporated  by  reference  to  the  sections  of  the  Proxy  Statement  entitled  “Security 

Ownership of Certain Beneficial Owners and Management.”  

92

                                   
   
Securities Authorized for Issuance Under Equity Compensation Plans  

The following table sets forth, as of December 31, 2009, certain information with respect to shares of our common stock

authorized for issuance under our equity compensation plans.  

Number of Securities Remaining

   Available for Future Issuance

Number of Securities to Weighted-Average Under Equity Compensation Plans
be Issued Upon Exercise
of Outstanding Options Outstanding Options

Exercise Price of

(Excluding Securities Reflected
in Column (A))
(C)

Plan Category

Equity compensation plans approved by 

security holders 

Equity compensation plans not 

approved by security holders (1) 

Total 

(A)

(B)

2,047,834 $

1,293,221 $

3,341,055

7.44

13.55

3,195,420

—

3,195,420

(1)   Includes  shares  issuable  upon  the  exercise  of  options  granted  under  the  Tm  Bioscience  Corporation  Share  Option  Plan
assumed by Luminex in connection with the acquisition of Tm Bioscience. These options have a weighted average exercise
price of $23.34. No further grants will be made pursuant to this plan. Also includes options to purchase 500,000 shares of
the Company’s common stock issued to Patrick J. Balthrop, Sr. on May 15, 2004 in connection with his hiring. Such option
grants were issued separate and apart from the Company’s stockholder approved equity incentive plans. 

ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE  

Information  required  by  this  Item  is  incorporated  by  reference  to  the  sections  of  the  Proxy  Statement  entitled  “Certain 

Relationships and Related Party Transactions” and “Corporate Governance.”  

ITEM 14. PRINCIPLE ACCOUNTING FEES AND SERVICES  

Information required by this Item is incorporated by reference to the section of the Proxy Statement entitled “Ratification of 

Appointment of Independent Registered Public Accounting Firm.”  

93

                                   
   
 
 
 
 
 
  
 
   
 
 
 
 
 
  
 
  
 
   
 
 
 
 
 
 
 
 
 
 
  
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
PART IV  

ITEM 15. EXHIBITS AND FINANCIAL STATEMENT SCHEDULES  

(a)   The following documents are filed as a part of this Annual Report on Form 10-K:

(1) Financial Statements:  

The Financial Statements required by this item are submitted in Part II, Item 8 of this report.  

(2) Financial Statement Schedules:  

All schedules are omitted because they are not applicable or the required information is shown in the Financial Statements
or in the notes thereto.  

(3) Exhibits:  

EXHIBIT  
NUMBER 

DESCRIPTION OF DOCUMENT

2.1  

3.1  

3.2  

4.1  

10.1#  

10.2#  

10.3#  

10.4#  

10.5#  

Merger  Agreement,  dated  December 14,  2006,  by  and  between  the  Company  and  Tm  Bioscience  Corporation
(Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed December 15, 2006). 

Restated Certificate of Incorporation of the Company (Previously filed as an Exhibit to the Company’s Registration 
Statement on Form S-1 (File No. 333-96317), filed February 7, 2000, as amended). 

Amended and Restated Bylaws of the Company (Previously filed as an Exhibit to the Company’s Current Report on 
Form 8-K, filed September 16, 2008). 

Rights Agreement dated as of June 20, 2001 between Luminex Corporation and Mellon Investor Services LLC, as
Rights Agent which includes as Exhibit A the form of Certificate of Designations of Series A Junior Participating
Preferred Stock setting forth the terms of the Series A Junior Participating Preferred Stock, as Exhibit B the form of
Rights  Certificate  and  as  Exhibit C  the  Summary  of  Rights  (Previously  filed  as  an  Exhibit  to  the  Company’s 
Current Report on Form 8-K dated June 21, 2001 (File No. 000-30109)).

Form of Incentive Stock Option Agreement for the 1996 Stock Option Plan (Previously filed as an Exhibit to the
Company’s Registration Statement on Form S-1 (File No. 333-96317), filed February 7, 2000, as amended).

2000  Long-Term  Incentive  Plan  of  the  Company,  as  amended  (Previously  filed  as  an  Exhibit  to  the  Company’s 
Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2002 (File No. 000-30109)). 

Form of Stock Option Award Agreement for the 2000 Long-Term Incentive Plan (Previously filed as an Exhibit to 
the Company’s Registration Statement on Form S-1 (File No. 333-96317), filed February 7, 2000, as amended).

2001  Broad-Based  Stock  Option  Plan  of  the  Company  (Previously  filed  as  an  Exhibit  to  the  Company’s  Annual 
Report on Form 10-K for the fiscal year ended December 30, 2001 (File No. 000-30109)). 

Form of Option Grant Certificate for the 2001 Broad-Based Stock Option Plan (Previously filed as an Exhibit to the
Company’s Annual Report on Form 10-K for the fiscal year ended December 30, 2001 (File No. 000-30109)).

94

                                   
   
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
EXHIBIT  
NUMBER 

10.6#  

10.7  

10.8  

10.9  

10. 10#  

10.11#  

DESCRIPTION OF DOCUMENT

Form of Indemnification Agreement between the Company and each of the directors and executive officers of the
Company (Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed September 16, 2008).

Lease  Agreement  between  Aetna  Life  Insurance  Company,  as  Landlord,  and  Luminex  Corporation,  as  Tenant,
dated October 19, 2001 (Previously filed as an Exhibit to the Company’s Form 10-Q for the quarterly period ended 
September 30, 2001 (File No. 000-30109)). 

First  Amendment  to  Lease  Agreement  between  Aetna  Life  Insurance  Company,  as  Landlord,  and  Luminex
Corporation as Tenant, dated July 25, 2002. (Previously filed as an Exhibit to the Company’s Quarterly Report on 
Form 10-Q for the period ended June 30, 2002 (File No. 000-30109)).

Lease Amendment between McNeil 4 & 5 Investors, LP, as Landlord, and Luminex Corporation, as Tenant, dated
January 27, 2003 (Previously filed as an Exhibit to the Company’s Annual Report on Form 10-K for the fiscal year 
ended December 31, 2002 (File No. 000-30109)).

Employment  Agreement,  effective  as  of  October 1,  2003,  by  and  between  Luminex  Corporation  and  Harriss  T.
Currie  (Previously  filed  as  an  Exhibit  to  the  Company’s  Annual  Report  on  Form 10-K  for  the  fiscal  year  ended 
December 31, 2003 (File No. 000-30109)). 

Employment Agreement effective as of October 1, 2003, by and between Luminex Corporation and David S. Reiter
(Previously  filed  as  an  Exhibit  to  the  Company’s  Annual  Report  on  Form 10-K  for  the  fiscal  year  ended 
December 31, 2003 (File No. 000-30109)). 

10.12#  

Employment  Agreement  effective  as  of  May 15,  2004,  by  and  between  Luminex  Corporation  and  Patrick  J.
Balthrop (Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed May 18, 2004).

10.13#  

Employment  Agreement  effective  as  of  October 25,  2004,  by  and  between  Luminex  Corporation  and  Gregory  J.
Gosch (Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed October 22, 2004).

10.14#  

Employment  Agreement  effective  as  of  May 23,  2005,  by  and  between  Luminex  Corporation  and  Russell  W.
Bradley (Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed May 25, 2005).

10.15#  

2009  Executive  Compensation  Summary  (Previously  filed  in  the  Company’s  Current  Report  on  Form 8-K  filed 
March 17, 2009). 

10.16#  

10.17#  

Form of Restricted Stock Agreement for the 2000 Long-Term Incentive Plan and 2001 Broad-Based Stock Option 
Plan  (Previously  filed  as  an  Exhibit  to  the  Company’s  Quarterly  Report  on  Form 10-Q  for  the  quarterly  period 
ended September 30, 2004 (File No. 000-30109)).

Form of Non-Qualified Stock Option Agreement dated as of May 15, 2004, by and between Luminex Corporation
and Patrick J. Balthrop (Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed May 18, 
2004 (File No. 000-30109)).

10.18#  

Form  of  Amendment  to  Executive  Employment  Agreements  (Previously  filed  as  an  Exhibit  to  the  Company’s 
Annual Report on Form 10-K for the fiscal year ended December 31, 2005).

10.19#  

Luminex  Corporation  Amended  and  Restated  2006  Equity  Incentive  Plan  (Previously  filed  as  an  Exhibit  to  the
Company’s Current Report on Form 8-K filed May 21, 2009). 

10.20#  

Form  of  Non-Qualified  Stock  Option  Agreement  for  the  Amended  and  Restated  2006  Equity  Incentive  Plan
(Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed May 21, 2009). 

10.21#  

Form of Restricted Share Award Agreement for Officers & Employees for the Amended and Restated 2006 Equity
Incentive Plan (Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed May 21, 2009).

95

                                   
   
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
EXHIBIT  
NUMBER 

10.22#  

DESCRIPTION OF DOCUMENT

Form  of  Restricted  Share  Award  Agreement  for  Directors  for  the  Amended  and  Restated  2006  Equity  Incentive
Plan (Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed May 21, 2009). 

10.23#  

Form of Restricted  Share Unit Agreement for Officers &  Employees for the  Amended and  Restated 2006 Equity
Incentive Plan (Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed May 21, 2009).

10.24#  

Form of Restricted Share Unit Agreement for Directors for the Amended and Restated 2006 Equity Incentive Plan
(Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed May 21, 2009). 

10.25#  

Luminex  Corporation  2006  Management  Stock  Purchase  Plan  (Previously  filed  as  Exhibit B  to  the  Company’s 
Proxy Statement for its Annual Meeting of Shareholders held on May 25, 2006).

10.26#  

10.27# 

10.28# 

Employment Agreement effective as of March 1, 2007, by and between Luminex Corporation, Tm Bioscience and
Jeremy Bridge-Cook (Previously filed as an Exhibit to the Company’s Annual Report on Form 10-K for the fiscal 
year ended December 31, 2006). 

Amendment to Restricted Stock Agreement, dated as of March 25, 2007, by and between Luminex Corporation and
Patrick J. Balthrop,  Sr. (Previously  filed  as  an  Exhibit  to  the Company’s Quarterly Report on  Form 10-Q for the 
quarterly period ended March 31, 2007). 

Amendment to Luminex Corporation Amended and Restated 2000 Long-Term Incentive Plan dated as of May 24, 
2007  (Previously  filed  as  an  Exhibit  to  the  Company’s  Quarterly  Report  on  Form 10-Q  for  the  quarterly  period 
ended June 30, 2007). 

10.29#  

Amendment to Luminex Corporation 2001 Broad-Based Stock Option Plan dated as of May 24, 2007 (Previously
filed as an Exhibit to the Company’s Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2007).

10.30#  

Amendment to Luminex Corporation 2006 Management Stock Purchase Plan dated as of May 24, 2007 (Previously
filed as an Exhibit to the Company’s Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2007). 

10.31#  

Luminex  Corporation  2008  Long  Term  Incentive  Plan  (Previously  filed  as  an  Exhibit  to  the  Company’s  Current 
Report on Form 8-K filed December 9, 2008).

10.32#  

Form  of  Restricted  Share  Unit  Award  Agreement  for  Awards  under  the  Luminex  Corporation  2008  Long  Term
Incentive  Plan  (Previously  filed  as  an  Exhibit  to  the  Company’s  Current  Report  on  Form 8-K  filed  December 9, 
2008). 

10.33#  

  Employment Agreement, dated as of July 1, 2009, by and between Luminex Corporation and Michael F. Pintek.

10.34#  

Luminex  Corporation  2009  Long  Term  Incentive  Plan  (Previously  filed  as  an  Exhibit  to  the  Company’s  Current 
Report on Form 8-K filed March 17, 2009). 

10.35#  

Form  of  Restricted  Share  Unit  Award  Agreement  for  Awards  under  the  Luminex  Corporation  2009  Long  Term
Incentive Plan (Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed March 17, 2009).

10.36#  

Form of Non-Qualified Stock Option Agreement for the 2006 Equity Incentive Plan (Previously filed as an Exhibit
to the Company’s Current Report on Form 8-K filed May 25, 2006).

10.37#  

Form  of  Restricted  Share  Award  Agreement  for  Officers  &  Employees  for  the  2006  Equity  Incentive  Plan
(Previously filed as an Exhibit to the Company’s Current Report on Form 8-K filed May 25, 2006). 

96

                                   
   
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
EXHIBIT  
NUMBER 

10.38#  

DESCRIPTION OF DOCUMENT

Form of Restricted Share Award Agreement for Directors for the 2006 Equity Incentive Plan (Previously filed as an
Exhibit to the Company’s Current Report on Form 8-K filed May 25, 2006). 

10.39#  

Form of Restricted Stock Unit Agreement for the 2006 Equity Incentive Plan (Previously filed as an Exhibit to the
Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2006). 

10.40#  

Form  of  Amendments  to  Equity  Award  Agreements  (Previously  filed  as  an  Exhibit  to  the  Company’s  Quarterly 
Report on Form 10-Q for the quarterly period ended June 30, 2007).

21.1  

  Subsidiaries of the Company. 

23.1  

  Consent of Independent Registered Public Accounting Firm.

24.1  

  Power of Attorney (incorporated in the signature page of this report).

31.1  

31.2  

32.1  

32.2  

Certification  by  CEO  pursuant  to  Securities  and  Exchange  Act  Rules 13a-14(a)  and  15d  —  14(a),  as  adopted 
pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

Certification  by  CFO  pursuant  to  Securities  and  Exchange  Act  Rules 13a-14(a)  and  15d  —  14(a),  as  adopted 
pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

Certification  by  CEO  pursuant  to  18  U.S.C.  Section 1350,  as  adopted  pursuant  to  Section 906  of  the  Sarbanes-
Oxley Act of 2002. 

Certification  by  CFO  pursuant  to  18  U.S.C.  Section 1350,  as  adopted  pursuant  to  Section 906  of  the  Sarbanes-
Oxley Act of 2002. 

#

  Management contract or compensatory plan or arrangement.

97

  
   
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
  
 
 
  
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
 
 
 
Pursuant  to  the  requirements  of  the  Section 13  or  15(d)  of  the  Securities  Exchange Act  of  1934,  the  Registrant  has  duly 

caused this Report to be signed on its behalf by the undersigned, thereunto duly authorized.  

SIGNATURES  

LUMINEX CORPORATION 

By:  /s/ Patrick J. Balthrop  
Patrick J. Balthrop 
President and Chief Executive Officer  
Date: February 25, 2010 

Pursuant to the requirements of the Securities Exchange Act of 1934, this Report has been signed below by the following 

persons on behalf of the Registrant and in the capacities and on the dates indicated.  

POWER OF ATTORNEY  

KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints 
Patrick J. Balthrop and Harriss T. Currie, each his true and lawful attorney-in-fact and agent, with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all capacities, to sign any and all amendments to this Report, 
and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities  and Exchange 
Commission, granting unto said attorneys-in-fact and agents, full power and authority to do and perform each and every act and 
thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he might or could do in 
person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or their substitutes or substitute, may lawfully 
do or cause to be done by virtue hereof.  

Pursuant to the requirements of the Securities Exchange Act of 1934, this Report has been signed below by the following 

persons on behalf of the registrant and in the capacities and on the dates indicated.  

S-1  

                                   
   
 
 
 
 
 
 
 
 
 
 
 
 
SIGNATURES

/s/ Patrick J. Balthrop  
Patrick J. Balthrop 

/s/ Harriss T. Currie  
Harriss T. Currie 

/s/ Robert J. Cresci  
Robert J. Cresci 

/s/ Thomas W. Erickson  
Thomas W. Erickson 

/s/ Fred C. Goad, Jr.  
Fred C. Goad, Jr. 

/s/ Jay B. Johnston  
Jay B. Johnston 

/s/ Jim D. Kever  
Jim D. Kever 

/s/ G. Walter Loewenbaum II  
G. Walter Loewenbaum II  

/s/ Kevin M. McNamara  
Kevin M. McNamara 

/s/ Edward A. Ogunro  
Edward A. Ogunro 

/s/ Gerard Vaillant  
Gerard Vaillant 

TITLE

DATE

President and Chief Executive Officer, 

February 25, 2010

  Chief Financial Officer, Vice President, 

February 25, 2010

Finance and Treasurer (Principal Financial Officer 
and Principal Accounting Officer)

  Director 

  Director 

  Director 

  Director 

  Director 

February 25, 2010

February 25, 2010

February 25, 2010

February 25, 2010

February 25, 2010

  Chairman of the Board of Directors 

February 25, 2010

  Director 

  Director 

  Director 

S-2

February 25, 2010

February 25, 2010

February 25, 2010

                                   
   
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
EXHIBIT 10.33  

EMPLOYMENT AGREEMENT  

THIS  EMPLOYMENT  AGREEMENT  (this  “Agreement”)  is  made  and  entered  into  as  of  July 1,  2009  (the  “Effective 

Date”) by and between Luminex Corporation, a Delaware corporation (“Luminex”) and Michael F. Pintek (“Executive”).  

RECITAL  

WHEREAS, Executive is to be employed as the Senior Vice President, Operations for Luminex;  

WHEREAS, Luminex and Executive wish to document the terms of the employment of Executive in such capacity; and  

WHEREAS,  Executive  has  represented  to  Luminex  and  Luminex  has  relied  on  Executive’s  representation  that  the 
execution  of  this  Agreement  by  Executive,  and  the  provision  of  services  by  Executive  to  Luminex  as  contemplated  in  this 
Agreement, will not conflict with, or cause Executive or any other person or entity to be in breach of, (i) any other contract to 
which Executive is a party or (ii) any duty which Executive may owe to any other person or entity.  

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, 

AGREEMENT  

the parties agree as follows:  

1. Duties.  

1.1  Duties.  During  the  term  of  this  Agreement  (including  all  renewal  periods,  if  any,  the  “Term”),  Executive 
agrees to be employed by and to serve as Senior Vice President, Operations and Luminex agrees to employ and retain Executive 
in such capacity subject to the provisions of this Agreement. Executive shall have such powers, authority and duties, and shall 
render such services of executive and administrative character, or act in such other capacity for Luminex, as the Chief Executive 
Officer or the Board of Directors of Luminex (the  “Board”)  shall from time to time lawfully direct and Executive shall report 
directly  to  the  Chief  Executive  Officer  of  Luminex.  Executive  shall  devote  all  of  his  business  time,  energy,  and  skill  to  the 
business of Luminex;  

2. Term and Termination.  

2.1  Term.  Subject  to  Section 2.2,  the  term  of  employment  of  Executive  by  Luminex  shall  be  two  (2) years 
commencing  on  the  Effective  Date  and  shall  thereafter  automatically  renew  for  successive  additional  one-year  terms  unless 
either party provides the  

Execution Version 

Confidential 

                                   
 
other with written notice of its intent not to renew this Agreement at least sixty (60) days prior to the end of the Term (unless 
terminated earlier pursuant to the provisions of this Agreement).  

2.2 Termination of Employment.  

2.2.1 Termination For Cause.  “Termination For Cause” shall mean the termination by Luminex of Executive’s 
employment  with  Luminex  as  the  result  of  Executive’s  material  fraud  upon  Luminex,  violation  of  the  law  or  Executive’s 
material breach of this Agreement after receipt of written notice from Luminex specifying such breach and failure by Executive 
to cure such breach within fifteen (15) days from receipt of such notice. Executive’s inability to perform his obligations under 
this Agreement despite his best efforts as a result of a permanent or temporary disability (as evidenced by a written determination 
from a physician chosen by Executive and reasonably acceptable to Luminex) shall not result in a Termination For Cause. In the 
event that Executive fails to cure the breach within the fifteen (15) day cure period, the termination shall be effective as of the 
date that Luminex notifies Executive of his termination following the expiration of the fifteen (15) day cure period. Upon any 
Termination  For  Cause,  Executive  shall  be  paid  the  Accrued  Obligations  (defined  below)  within  three  (3) business  days 
following the effective date of termination.  

2.2.2  Termination  Other  Than  For  Cause.  “Termination  Other  Than  For  Cause”  shall  mean  (i) termination  by 
Luminex of Executive’s employment with Luminex for any reason other than Termination For Cause, Termination by Reason of 
Death,  Termination  by  Reason  of  Incapacity  or  Termination  Upon  Expiration  of  Agreement  or  (ii) termination  by  Executive 
upon constructive termination of Executive’s employment with Luminex by reason of (A) a reduction in Executive’s Base Salary 
(defined  below);  (B) a  reduction  in  Executive’s  title  from  Chief  Operating  Officer  for  Luminex  (whether  by  reason  of 
Executive’s removal from any of such offices or Luminex’s failure to reappoint Executive to any of such offices); (C) a Material 
Diminution (defined below); (D) a requirement that Executive change his principal place of business to a location that is outside 
the  Office Area (defined below), or (E) Luminex’s continued material breach of this  Agreement after receipt of written notice 
from Executive specifying such breach and failure by Luminex to cure such breach within fifteen (15) days from receipt of such 
notice. Termination Other Than For Cause may be effected by Luminex at any time by providing Executive with written notice 
of such termination. The termination shall be effective as of the date of the notice or such later date as may be determined by 
Luminex. Executive may also effect a Termination Other Than For Cause upon written notice to Luminex at any time any of the 
conditions for constructive termination set forth in clause (ii) above (including without limitation, if applicable, the expiration of 
the  cure  period)  have  been  met.  Upon  any  Termination  Other  Than  For  Cause,  Executive  shall  be  paid  (i) within  three 
(3) business  days  following  the  effective  date  of  termination  the  amount  of  the  Accrued  Obligations  and  (ii) all  severance 
compensation provided in Section 4.1. For purposes of this Agreement, “Material Diminution” means a material diminution by 
Luminex of Executive’s duties, powers, authority, functions or responsibilities without Executive’s consent, such that Executive 
is  left  with  such  duties,  powers,  authority,  functions  and  responsibilities  (when  viewed  in  the  aggregate)  that  are  materially 
diminished compared to both (i) those duties, powers, authority, functions and responsibilities conferred upon Executive at the 
Effective Date and (ii) those duties, powers, authority, functions and responsibilities that are most typically conferred upon  

Execution Version 

- 2

                                   
   
the chief operating officer of companies having both (i) a chief operating officer and (ii) revenues comparable to Luminex (based 
on the revenues of Luminex at the time of determination). Luminex and Executive agree that in the event there is an ambiguity 
with  respect  to  the  interpretation  or  application  of  the  definition  of  “Material  Diminution”,  such  ambiguity  shall  be  resolved 
according to the reasonable interpretation of such definition most favorable to Luminex. For purposes of this Agreement, “Office 
Area”  means  the  geographical  area  within  a  40  mile  radius  of Luminex’s current  principal office at  12212  Technology Blvd., 
Austin, Texas.  

2.2.3  Actual  Voluntary  Termination.  “Actual  Voluntary  Termination”  shall  mean  termination  by  Executive  of 
Executive’s employment with Luminex for any reason other than Termination For Cause, Termination Other Than For Cause, 
Termination  by  Reason  of  Death  or  Termination  by  Reason  of  Incapacity.  In  the  event  of  an  Actual  Voluntary  Termination, 
Executive shall be paid within fifteen (15) business days following the effective date of termination the amount of the Accrued 
Obligations.  

2.2.4 Termination by Reason of Incapacity. If, during the Term, Executive shall become Permanently Disabled 
(defined below), Luminex may terminate Executive’s employment with Luminex effective on the earliest date permitted under 
applicable  law,  if  any,  and  such  termination  shall  be  deemed  “Termination  by  Reason  of  Incapacity”.  Upon  termination  of 
employment  under  this  Section,  Executive  shall  be  paid  (i) within  three  (3) business  days  following  the  effective  date  of 
termination the amount of the Accrued Obligations and (ii) all severance compensation provided in Section 4.2. As used herein, 
Executive  shall  be  deemed  “Permanently  Disabled”  if  Executive  is  (i)  collecting  long-term  disability  payments  under  a  long-
term disability plan established for the benefit of Luminex’s employees or executives generally or a reasonably similar plan or 
(ii) if, and only if, no such long-term disability plan is in effect at the time of determination, a physician selected by Luminex and 
reasonably acceptable to Executive makes a written determination that Executive is unable to perform his obligations under this 
Agreement despite his best efforts by reason of any medically determinable physical or mental impairment that can be expected 
to result in death or that has lasted or can be expected to last for a continuing period of not less than 12 months.  

2.2.5  Termination  by  Reason  of  Death.  In  the  event  of  Executive’s  death  during  the  Term,  Executive’s 
employment  with  Luminex  shall  be  deemed  to  have  terminated  as  of  the  date  on  which  his  death  occurs  and  the  estate  of 
Executive  shall  be  paid  (i) within  fifteen  (15) days  following  the  effective  date  of  termination  the  amount  of  the  Accrued 
Obligations and (ii) all severance compensation provided in Section 4.3.  

2.2.6 Termination Upon Expiration of Agreement. In the event that Luminex refuses for any reason to extend this 
Agreement  by  giving  written  notice  at  least  60 days  prior  to  the  initial  or  any  renewal  period  as  set  forth  in  Section 2.1, 
Executive shall be paid (i) within three (3) business days following the effective date of termination the amount of the Accrued 
Obligations  and  (ii) all  severance  compensation  provided  in  Section 4.4.  In  the  event  that  Executive  refuses  for  any  reason 
(except as otherwise provided herein) to extend this Agreement by giving written notice at least 60 days prior to the initial or any 
renewal period as set forth in Section 2.1, the termination shall be deemed an Actual Voluntary Termination.  

Execution Version 

- 3 -

                                   
   
2.2.7  Termination  of Relationship  with Affiliated  Entities.  Unless  agreed by  Luminex  (or  a subsidiary  thereof) 
and  Executive  in  a  separate  written  agreement  (other  than  corporate  minutes,  resolutions,  charter  documents,  bylaws  and 
partnership agreements), upon the termination of Executive’s employment with Luminex for any reason, Executive shall tender a 
written resignation of any positions he may have with Luminex and any and all of Luminex’s direct and indirect subsidiaries.  

2.2.8  Definition of  Accrued Obligations. As used in this Agreement,  “Accrued  Obligations”  means  all  accrued 
but  unpaid  salary,  accrued  but  unpaid  vacation,  sick  leave,  and  similar  pay  (all  determined  in  accordance  with  Luminex’s 
policies then in effect), and any appropriate business expenses incurred by Executive in connection with his duties hereunder, all 
to the date of termination.  

3. Salary, Benefits and Bonus Compensation.  

3.1 Base Salary. As payment for the services to be rendered by Executive as provided in Section 1 and subject to 
the terms and conditions of Section 2, Luminex agrees to pay to Executive a “Base Salary” at the rate of $13,125.00 per each 
semi-monthly pay period or $315,000 per annum (or such greater amount as may be determined from time to time by the Board
or the Compensation Committee thereof) payable in accordance with the then-current payroll policies of Luminex.  

3.2  Signing  Bonus.  Executive  shall  receive  an  initial  signing  bonus  in  the  amount  of  $100,000,  payable  to 
Executive upon the Effective Date of this Agreement (the “Signing Bonus”). Executive may receive an additional discretionary 
signing bonus (the “Additional Signing Bonus”) at the sole discretion of the Compensation Committee of the Company’s Board 
of Directors. In addition, the Company shall pay an additional amount to Executive, calculated as hereinafter described, designed 
to  reimburse  Executive  for  any  federal  and  state  income  and  Medicare  tax  withholdings  required  by  applicable  law  on  the 
Signing  Bonus  and  the  Additional  Signing  Bonus  (the  “Gross-up  Amount”).  Executive  agrees  that  he  shall  be  obligated  to 
promptly  repay  to  Company the  “pro  rata amount”  of  the aggregate  amount of the  Signing  Bonus  and  the  Additional  Signing 
Bonus  (if  any)  and  the  Gross-up  Amount  (the  “Total  Signing  Bonus”)  in  the  event  of  “Termination  for  Cause”  pursuant  to 
Section 2.2.1 or in the event of “Actual Voluntary Termination” pursuant to Section 2.2.3 within three (3) years of the Effective 
Date.  The “pro rata amount” shall be determined by multiplying the Total Signing Bonus by a fraction determined by dividing 
the number of days remaining from the date of the termination event through the date that is three (3) years from the Effective 
Date,  by  1095.  The  Gross-up  Amount  shall  be  determined  by  dividing  the  aggregate  amount  of  the  Signing  Bonus  and,  if 
applicable the Additional Signing Bonus, by .635, which applies the federal income tax at a 35% rate, Medicare tax at a 1.45% 
rate and no state income tax. In the event state income tax shall be applicable to these payments, an appropriate adjustment for 
the net applicable state income tax rate shall be made to this calculation.  

3.3  Annual  Bonus.  Executive  shall  be  eligible  to  receive  a  bonus  each  year  in  an  amount  up  to  at  least  fifty 
percent (50%) of your then-current Base Salary (or such other amount as may otherwise be determined by the Company’s Board 
of Directors), subject to the  

Execution Version 

- 4 -

                                   
   
performance  criteria  established  annually  by  the  Company’s  Board  of  Directors  and  payable  during  the  first  quarter  of  the 
following  year  or  otherwise  as  consistent  with  the  timing  of  other  employee  bonuses.  The  Board  is  under  no  obligation  to 
declare,  and  Luminex  is  under  no  obligation  to  pay,  any  bonus  to  Executive  under  the  terms  of  this  Agreement.  In  the  event 
Executive and Luminex are parties to a written agreement or plan executed by both Luminex and Executive that governs bonus 
arrangements, and the provisions thereof conflict with this Section 3.3, the terms of such other written agreement or plan shall 
supersede this Section 3.3. Notwithstanding the foregoing, Executive shall be eligible to receive a prorata portion of any bonus 
awarded for 2009 based on the number of months Executive is employed by the Company during 2009.  

3.4 Change in Control. In the event that both (i) a Change in Control (defined below) of Luminex occurs during 
the Term and (ii) Executive’s employment with Luminex (or, as applicable, its successor in interest) terminates for any reason 
(including  without  limitation  an  Actual  Voluntary  Termination by  Executive)  at  any  time  within  six  (6) months  following  the 
occurrence of the Change in Control of Luminex, in lieu of any Severance Compensation then owed or that otherwise would be 
owed in the future to Executive under Section 4  of this  Agreement, Luminex (or its successor in interest)  shall pay Executive 
both the Accrued Obligations and a lump sum payment (the “Change in Control Payment”) in an aggregate amount equal to the 
sum of (i) the Bonus Amount (defined below), plus (ii) an amount equal to Executive’s annual Base Salary (at the highest rate in 
effect during the period beginning six months immediately prior to the effective date of the Change of Control through the date 
of  termination)  within  three  (3) business  days  after  the  termination  of  Executive’s  employment.  In  the  interest  of  clarity, 
Luminex and Executive agree that, upon the termination of Executive’s employment at any time within six (6) months following 
the occurrence of the Change in Control of Luminex, the provisions of Sections 4.1, 4.2, 4.3, 4.4, and 4.6 shall automatically be 
deemed null and void and shall not apply with respect to any termination of Executive’s employment (whether such termination 
is effected in connection with the Change in Control of Luminex or at any time in the future following the Change in Control of 
Luminex), and under no circumstances shall Luminex ever be obligated to pay Executive both a Change in Control Payment and 
Severance Compensation under Section 4. For purposes of this Agreement, a “Change in Control” of Luminex shall be deemed 
to have occurred if, after the date of this Agreement:  

(A) any  “Person” (as such term is used in Sections 13(d) and 14(d) of the Securities Exchange Act of 1934, as amended 
(the  “Exchange  Act”))  (other  than  an  Approved  Person  (as  defined  below))  becomes  the  “Beneficial  Owner”  (as  defined  in 
Rule 13d-3  under  the  Exchange  Act),  directly  or  indirectly,  of  a  majority  or  more  of  the  then  outstanding  Common  Stock  of
Luminex (“Common Stock”) (such Person, an “Acquiring Person”); or  

(B) Luminex  merges  or  consolidates  with  any  other  corporation  or  other  entity,  in  each  case  other  than  a  merger  or 
consolidation  which  results  in  the  voting  securities  of  Luminex  outstanding  immediately  prior  thereto  continuing  to  represent 
(either by remaining outstanding or by being converted into voting securities of the surviving entity) at least a majority of the 
combined voting power of the voting securities of Luminex or such surviving entity outstanding immediately after such merger 
or consolidation; or  

Execution Version 

- 5 -

                                   
   
(C) Luminex  sells  or  disposes  of  all  or  substantially  all  of  Luminex’s  assets  in  one  transaction  or  a  series  of  related 

transactions; or  

(D) Luminex  files  a  periodic  or  current  report  or  proxy  statement  with  the  Securities  and  Exchange  Commission  (the 
“SEC”) disclosing that a “change in control” (as such term is used in Item 1 of Form 8-K promulgated by the SEC) of Luminex 
has occurred; or  

(E) If, as a result of nominations made by a person or group other than the Board of Directors of Luminex, individuals who 
prior to such nominations constitute the Directors of Luminex cease for any reason to constitute at least a majority thereof within 
the two year period following such nominations.  

As  used  in  this  Agreement,  “Approved  Person”  means  (1) an  employee  benefit  plan  of  Luminex  (or  a  trustee  or  other 
fiduciary holding securities for such a plan), or (2) a corporation owned, directly or indirectly, by the stockholders of Luminex in 
substantially  the  same  proportions  as  their  ownership  of  stock  of  Luminex,  or  (3) a  Person  not  less  than  a  majority  of  whose 
voting securities are Beneficially Owned by Luminex after giving effect to the transaction.  

As used in this Agreement, “Bonus Amount” means the annual bonus (if any) received or to be received by Executive under 
Section 3.2  in  respect  of  the  then most  recently  completed calendar  year,  or if  no  determination  concerning  bonuses  has been 
made for the most recently completed calendar year, then the annual bonus (if any) for the previous calendar year.  

Any  options  (“Options”)  granted  (including  without  limitation  Options  that  may  be  granted  in  the  future)  and  restricted 
stock  (“Restricted  Stock”)  issued (including  without  limitation Restricted Stock  that  may be  issued in the  future) to Executive 
pursuant to any  incentive  plan  of  Luminex shall immediately vest upon a  Change in Control. Luminex shall take  no  action  to 
facilitate a transaction involving a Change in Control, including without limitation redemption of any rights issued pursuant to 
any rights agreement, unless it has taken such action as may be necessary to ensure that Executive has the opportunity to exercise 
all Options he may then hold, and obtain certificates containing no restrictive legends in respect of any Restricted Stock he may 
then  hold,  at  a  time  and  in  a  manner  that  shall  give  Executive  the  opportunity  to  sell  or  exchange  the  securities  of  Luminex 
acquired upon exercise of his Options and upon receipt of unrestricted certificates for shares of Common Stock in respect of his 
Restricted Stock, if any (collectively, the “Acquired Securities”), at the earliest time and in the most advantageous manner any
holder of the  same  class of securities  as  the Acquired Securities is able to  sell or exchange  such securities in connection with 
such Change in Control. Luminex acknowledges that its covenants in the preceding sentence (the “Covenants”)  are reasonable 
and necessary in order to protect the legitimate interests of Luminex in maintaining Executive as one of its employees and that 
any  violation  of  the  Covenants  by  Luminex  would  result  in  irreparable  injuries  to  Executive,  and  Luminex  therefore 
acknowledges that in the event of any violation of the Covenants by Luminex or its directors, officers or employees, or any of 
their respective agents, Executive shall be entitled to obtain from any court of competent jurisdiction temporary, preliminary and 
permanent injunctive relief in order to (i) obtain specific performance of the Covenants, (ii) obtain specific performance of the 
exercise of his Options, delivery of certificates  

Execution Version 

- 6 -  

                                   
   
containing  no  restrictive  legends  in  respect  of  his Restricted  Stock  and  the sale  or exchange of  the Acquired  Securities  in  the 
advantageous manner contemplated above or (iii) prevent violation of the Covenants; provided nothing in this Agreement shall 
be deemed to prejudice Executive’s rights to damages for violation of the Covenants. In the event that the terms of any separate 
written agreement concerning Options granted or Restricted Stock issued to Executive conflict with the terms of this paragraph, 
the terms of this paragraph shall control.  

3.5 Additional Benefits. During the Term, Executive shall be entitled to the following fringe benefits:  

3.5.1 Transitional Expenses. The Company will pay for the following additional expenses upon presentation of 
applicable receipts: i) the costs of your temporary living until you purchase a home, at a rate of per month to be agreed upon by 
you  and me  for  up  to  a  period  of  three  (3) months;  ii) the costs of  a  rental  car until your automobile arrives  in  Austin or  you 
purchase an automobile, which is expected to be for a period of no more than one (1) month; iii) the costs of your airfare to and 
from California for up to two (2) trips per month for a period of up to three (3) months, not to exceed $1,000 per month; iv) the 
costs of up to two (2) house hunting trips for you and your spouse.   

3.5.2 Benefits and Vacation. Executive shall be eligible to participate in such of Luminex’s benefits and deferred 
compensation  plans  as  are  now  generally  available  or  later  made  generally  available  to  executive  officers  of  Luminex.  A 
termination or expiration of this Agreement for any reason or for no reason shall not affect any rights which Executive may have 
pursuant to any agreement, policy, plan, program or arrangement of Luminex providing Executive benefits (including under any 
stock  option  agreement  or  bonus  plan  or  agreement  which  may  exist),  which  rights  shall  be  governed  by  the  terms  thereof. 
Executive  shall  be  entitled to four (4) weeks paid vacation each  calendar  year  (prorated for partial years).  Unless approved  in 
advance by the Board or a committee thereof, accrued vacation not taken in any applicable period shall not be carried forward or 
used in any subsequent period.  

3.5.3 Reimbursement for Expenses.  

3.5.3.1  Incidental  Expenses.  Luminex  shall  reimburse  Executive  for  reasonable  and  properly  documented 
out-of-pocket business and/or entertainment expenses incurred by Executive in connection with his duties under this Agreement. 
Any such expenses shall be submitted by Executive to Luminex on a periodic basis and will be paid in accordance with standard 
Luminex policies and procedures.  

3.5.3.2  Moving  Expenses.  In  the  event  of  the  relocation  of  Luminex’s  headquarters  to  a  location  that  is 
outside the Office Area and Executive elects to relocate, Luminex shall (i) reimburse Executive for any reasonable, out-of-pocket 
and adequately documented moving expenses incurred by Executive in connection with the transfer of his residence and (ii) pay 
to an Executive an amount of cash reasonably calculated by Luminex to negate adverse income tax consequences to Executive of 
the foregoing reimbursement.  

Execution Version 

- 7 -

                                   
   
4. Severance Compensation.  

4.1  Severance  Compensation  in  the  Event  of  a  Termination  Other  Than  For  Cause.  In  the  event  Executive’s 
employment is terminated as a result of a Termination Other Than for Cause, Executive shall be paid (subject to Section 4.6) the 
Severance Compensation (defined below).  

4.2 Severance Compensation for Termination by Reason of Incapacity. In the event Executive’s employment is 
terminated as a result of a Termination by Reason of Incapacity, Executive shall be paid (subject to Section 4.6) the difference of 
(i) the Severance Compensation  less (ii) any payment or payments received by Executive during the twelve (12) month  period 
from the time of termination under any long-term disability plan in effect that provides benefits to Executive.  

4.3  Severance  Compensation  for  Termination  by  Reason  of  Death.  In  the  event  Executive’s  employment  is 

terminated as a result of Executive’s death, the estate of Executive shall be paid the Severance Compensation.  

4.4  Severance  Compensation  In  the  Event  Of  A  Failure  Of  Luminex  To  Renew  This  Agreement.  In  the  event 
Luminex  fails  or  otherwise  refuses  for  any  reason  to  extend  this  Agreement  beyond  the  Term  and  any  extensions  thereof, 
Executive shall be paid (subject to Section 4.6) the Severance Compensation.  

4.5 No  Severance Compensation Upon Other Termination. In the event of an Actual Voluntary Termination or 

Termination For Cause, Executive shall not be paid any severance compensation.  

4.6 Conditions to Payment; Sole Remedy. Executive shall not be entitled to receive any compensation or other 
payment  pursuant  to  Sections 4.1,  4.2  or  4.4  unless  Executive  shall  have  executed  and  delivered  to  Luminex  a  release 
substantially  in  the  form  attached  hereto  as  Exhibit  “A”  and,  provided  Luminex  has  also  signed  such  release  within  two 
(2) business  days  of  execution  and  delivery  by  Executive,  all  revocation  and  waiting  periods  applicable  to  such  release  have 
expired (if Luminex fails to sign such release, then such revocation and waiting periods shall not apply). In addition, in the event 
that  Executive  breaches  any  of  the  restrictive  covenants  set  forth  in  Article 5  at  any  time,  Luminex  shall  be  entitled  to 
discontinue  any  compensation  or  other  payments  pursuant  to  Sections 4.1,  4.2  or  4.4  (provided,  however,  that  if  it  is  finally 
determined by a court of competent jurisdiction or an arbitrator that Luminex asserted in bad faith that Executive breached any of 
the restrictive covenants set forth in Article 5, the payments of the Severance Compensation shall be extended for two months for 
each calendar month that payments were delayed. The compensation to be paid to Executive pursuant to Sections 4.1, 4.2, 4.3 or 
4.4 shall represent  the sole and exclusive remedy of Executive in  connection  with the termination of his employment  and this 
Agreement upon a Termination Other Than for Cause, a Termination by Reason of Incapacity, a termination in connection with 
Executive’s death, or a refusal by Luminex to extend this Agreement beyond the Term and any extensions thereof.  

Execution Version 

- 8 -  

                                   
   
4.7  Definition  of  Severance  Compensation.  As  used  in  this  Agreement,  “Severance  Compensation”  means  an 
amount equal to the sum of (i) the Bonus Amount plus (ii) an amount equal to Executive’s annual Base Salary (at the highest rate 
in effect for the six month period immediately prior to the date of termination), paid in semi-monthly installments for a period of 
twelve (12)  months  from the date of termination. In addition, as part of the  Severance Compensation,  Luminex also shall pay 
(until the earlier of (A) the first annual anniversary of the termination of this Agreement or (B) the date that Executive is eligible 
to  be  covered  under  a  comparable  or  more  favorable  health  plan  of  another  Person)  (i) COBRA  payments  in  respect  of  the 
continuation  of  health  benefits  for  Executive,  his  spouse  and  his  children  and  (ii) payments  to  fund  dental  coverage  for 
Executive,  his  spouse  and  his  children  comparable  to  the  dental  coverage  that  they  would  have  received  if  Executive  had 
continued as an employee of Luminex.  

5. Protection of Luminex.  

5.1 Non-Competition. Ancillary to the otherwise enforceable agreements set forth in this Agreement, Executive 
agrees that during Executive’s employment  with Luminex and  for  a  period of one year following termination of employment, 
whether such termination occurs at the insistence of Executive or Luminex for any reason, Executive shall not compete directly 
or  indirectly  in  any  way  with  the  business  of  Luminex  anywhere  in  the  world  where  Luminex  conducted  business  during  the 
Term.  For  purposes  of  this  Agreement,  “compete  directly  or  indirectly  in  any  way  with  the  business  of  Luminex”  means  to 
become  an  employee,  consultant,  advisor,  manager,  member,  director  of  or  beneficially  own  more  than  three  percent  of  any 
individual, company or entity that  competes with Luminex in the  Core Business (defined below) at the time of determination. 
Executive  agrees  that  the  assertion  or  existence  of  any  claim  by  Executive  against  Luminex  shall  not  be  a  defense  to  the 
enforcement of this paragraph by injunction or otherwise. As used in this Agreement, “Core Business” means the development, 
manufacturing and/or marketing of multiplexing biological testing technologies with applications in the life-sciences industry.  

5.2  Nonsolicitation.  Ancillary  to  the  otherwise  enforceable  agreements  set  forth  in  this  Agreement,  Executive 
agrees that, for a period of one (1) year subsequent to the termination of Executive’s employment with Luminex, whether such 
termination  occurs  at  the  insistence  of  Executive  or  Luminex  for  any  reason,  Executive  shall  not  recruit,  hire,  or  attempt  to 
recruit or hire, directly or by assisting others, any other employees of Luminex, nor shall Executive contact or communicate with 
any other employees of Luminex for the purpose of inducing other employees to terminate their employment with Luminex. For 
purposes of this covenant, “other employees of Luminex” shall refer to employees who are still actively employed by, or doing 
business with, Luminex or a subsidiary of Luminex at the time of the attempted recruiting or hiring.  

5.3 Remedies. Due to the irreparable and continuing nature of the injury which would result from a breach of the 
covenants described in Sections 5.1 and 5.2, Executive agrees that Luminex may, in addition to any remedy which Luminex may 
have at law or in equity, apply to any court of competent jurisdiction for the entry of an immediate order to restrain or enjoin the 
breach of this covenant and to otherwise specifically enforce the provisions of the covenants set forth in Sections 5.1 and 5.2.  

Execution Version 

- 9 -

                                   
   
5.4 Acknowledgment. Executive acknowledges and agrees that the restrictions set forth above are ancillary to an 
otherwise enforceable agreement and supported by independent valuable consideration as required by TEX. BUS. & COMM. CODE
ANN. § 15.50. Executive further acknowledges and agrees that the limitations as to time, geographical area, and scope of activity 
to be restrained by Sections 5.1 and 5.2 are reasonable and acceptable to Executive, and do not impose any greater restraint than 
is reasonably necessary to protect the goodwill and other business interests of Luminex.  

5.5  Reformation  and  Severance.  If  a  judicial  determination  is  made  that  any  of  the  provisions  of  the  above 
restriction constitutes an unreasonable or otherwise unenforceable restriction against Executive, it shall be rendered void only to 
the extent that such judicial determination finds such provisions to be unreasonable or otherwise unenforceable. In this regard, 
the  parties  hereby agree that any  judicial authority construing  this Agreement shall be empowered to  sever any portion  of the 
prohibited  business  activity  from  the  coverage  of  this  restriction  and  to  apply  the  restriction  to  the  remaining  portion  of  the 
business  activities  not  so  severed  by  such  judicial  authority.  Moreover,  notwithstanding  the  fact  that  any  provisions  of  this 
restriction are determined by a court not to be specifically enforceable through injunctive relief, Luminex shall nevertheless be 
entitled to seek to recover monetary damages as a result of the breach of any provision which is not reformed by a court. The 
time  period  during  which  the  restrictions  shall  apply  shall  be  tolled  and  suspended  as  to  Executive  for  a  period  equal  to  the 
aggregate quantity of time during which Executive violates such prohibitions in any respect.  

5.6  Confidential Information and Trade Secrets. As used  herein,  “Confidential Information” means any  data or 
information  that  is  important,  competitively  sensitive,  and  not  generally  known  by  the  public  or  persons  involved  in  the 
biological  testing  or  life  sciences  industries,  including,  but  not  limited  to,  Luminex’s  business  plans,  Prospective  Customers, 
training manuals, proprietary software, product development plans, bidding and pricing procedures, market plans and strategies, 
projections, internal performance statistics, financial data, confidential personnel information concerning employees of Luminex, 
operational  or  administrative  plans,  policy  manuals,  and  terms  and  conditions  of  contracts  and  agreements.  The  term 
“Confidential Information” shall not apply to information which is (i) already in Executive’s possession (unless such information 
was  obtained  by  Executive  from  Luminex  in  the  course  of  Executive’s  employment  by  Luminex);  (ii) received  by  Executive 
from a third party with, to Executive’s knowledge, no restriction on disclosure or (iii) required to be disclosed by any applicable 
law or by an order of a court of competent jurisdiction.  

Executive recognizes and acknowledges that the Confidential Information constitutes valuable, special and unique assets of 
Luminex and its affiliates. Except as required to perform Executive’s duties as an Executive of Luminex, until such time as they 
cease  to  be  Confidential  Information  through  no  act  of  Executive  in  violation  of  this  Agreement,  Executive  will  not  use  or 
disclose any Confidential Information of Luminex. Upon the request of Luminex and, in any event, upon the termination of this 
Agreement for any reason, Executive will surrender to Luminex (i) all memoranda, notes, records, drawings, manuals or other 
documents pertaining to Luminex’s business including all copies and/or reproductions thereof and (ii) all materials involving any 
Confidential Information of Luminex.  

Execution Version 

- 10 -

                                   
   
5.7  Preservation  of  Luminex  Property.  Executive  acknowledges  that  from  time  to  time  in  the  course  of 
employment with Luminex, Executive has had the opportunity to inspect and use certain property of Luminex, both tangible and 
intangible, including  but  not  limited  to  files,  records,  documents,  drawings,  specifications,  lists,  equipment,  graphics,  designs, 
and similar items relating to the business of Luminex. Executive acknowledges and agrees that all such property, including but 
not limited  to  any and  all copies thereof,  whether  prepared  by Executive or otherwise  in  the possession  of Executive,  are  and 
shall remain the exclusive property of Luminex, that Executive shall have no right or proprietary interest in such property and 
that  Executive  will  safeguard  and  return  to  Luminex  all  such  property  upon  the  earlier  of  (i) Luminex’s  request  and  (ii) the 
termination of Executive’s employment with Luminex.  

5.8  Assignment  of  Inventions  to  Luminex.  All  computer  software,  compilations,  programs,  improvements, 
inventions, notes, copyrightable works, and opportunities for additional Luminex business, made, fixed, conceived, or acquired 
by Executive during the Term are exclusively owned by Luminex, are Luminex’s works for hire, and fully assigned to Luminex 
including without limitation all rights to renewals, extensions, causes of action, reproduce, prepare derivative works, distribute, 
display,  perform,  transfer,  make, use and  sell  and may  never be copied, used, or disclosed without  Luminex’s express  written 
consent. Executive will sign on request any documents affirming the same for any particular item. In addition, Executive agrees 
to execute Company’s standard Confidentiality and IP Assignment Agreement by the Effective Date.  

5.9  Notice  to  Subsequent  Employers.  Executive  agrees  that,  prior  to  commencing  any  new  employment  in  the 
Core Business  within  twelve months after the  termination of this Agreement, Executive will furnish  the new employer with  a 
copy of this Agreement. Executive also agrees that Luminex may advise any new or prospective employer of the existence and 
terms of this Agreement and furnish the employer with a copy of this Agreement.  

6. Disclosure of Investments. Commencing upon Executive’s execution of this Agreement and at all times during the 
Term, Executive shall keep the Board informed in writing of the nature and extent of Executive’s investments, stock holdings, or 
retention  as  a  director,  advisor  or  any  similar  interest  in  any  business  or  enterprise  involved  in  the  Core  Business  other  than 
Luminex;  provided,  however,  that  Executive  shall  not  be  required  to  disclose  any  such  investments  or  stock  holdings  that 
constitute less than 1% of such entity’s total obligations or total voting power.  

7. Arbitration.  

7.1  Exclusive  Remedy.  Arbitration  shall  be  the  sole  and  exclusive  remedy  for  resolving  any  claim  or  dispute 
which  cannot  be  mutually  resolved  between  the  parties  to  this  Agreement  with  the  exception  of  disputes  arising  out  of 
Executive’s obligations under Article 5 or disputes arising out of Luminex’s obligations under the last paragraph of Section 3.4, 
which are not subject to this arbitration provision; provided however, that the parties hereto agree that they may bring action in 
any court of competent jurisdiction to enforce any award granted pursuant to arbitration or to otherwise enforce this Article 7. 
This includes, but is not limited to,  

Execution Version 

- 11 -

                                   
   
termination, interpretation or application of this Agreement or any other agreement or policy of Luminex, any claim of violation 
of law relating to the employment relationship, including, without limitation, any claim of employment discrimination or sexual 
harassment, or harassment based on any other prohibited basis, or any claim by Luminex against Executive. This Agreement is a 
waiver of the right to trial by a jury or court.  

7.2  Limitations.  The  request  for  arbitration  must  be  made  within  one  (1) year  from  the  date  of  the  occurrence 

giving rise to the dispute or claim; or, in the event of a statutory claim, the time set forth by statute.  

7.3  Rules  and  Procedures.  The  arbitration  will  be  conducted  under  the  rules  and  procedures  for  arbitration  of 
employment disputes of the American Arbitration Association. The arbitration shall take place in Austin, Texas unless the parties 
mutually agree to another location.  

7.4 Arbitrator’s Authority. Upon finding that a claim is meritorious or in favor of one of the parties to the dispute, 

the arbitrator or arbitrators shall have the authority to order legal and equitable remedies appropriate as permitted by law.  

7.5 Expenses. Costs of obtaining and paying the arbiter and the costs associated with conducting the arbitration, 
including obtaining a facility to be used during the arbitration, shall be paid by Luminex. Other costs of the arbitration or any 
litigation  associated  with  any  dispute  arising  under  or  in  connection  with  this  Agreement  including,  without  limitation, 
reasonable attorneys’ and experts’ fees and expenses of Luminex and the Executive shall be borne by the party incurring such 
expense unless the arbiter or court of law, as the case may be, awards costs to one of the parties.  

8. Miscellaneous.  

8.1 Waiver. The waiver of the breach of any provision of this Agreement shall not operate or be construed as a 

waiver of any subsequent breach of the same or other provision hereof.  

8.2  Entire  Agreement;  Modifications. Except as  otherwise provided  herein,  this Agreement  represents the  sole, 
entire, and complete understanding among the parties with respect to the subject matter hereof, and this Agreement supersedes 
any and all prior understandings, agreements, plans and negotiations, whether written or oral, with respect to the subject matter 
hereof, including without limitation any understandings, agreements or obligations respecting any past or future compensation, 
bonuses, reimbursements or other payments to Executive from Luminex. All modifications to the Agreement must be in writing 
and signed by both Executive and Luminex.  

8.3 Notices. All notices and other communications under this Agreement shall be in writing and shall be given by 
facsimile or first class mail, certified or registered with return receipt requested, and shall be deemed to have been duly  given 
three business days after  

Execution Version 

- 12 -

                                   
   
mailing  or  one  business  day  after  transmission  of  a  facsimile  (with  confirmation  of  receipt)  to  the  respective  persons  named 
below:  

If to Luminex:  

If to Executive:  

Luminex Corporation
Attn: General Counsel
12212 Technology Blvd.
Austin, Texas 78727
Fax: (512) 219-6325

Mr. Michael F. Pintek
5 MacGregor Place
Danville, CA 94526

Any party may change such party’s address for notices by notice duly given pursuant to this Section 8.3.  

8.4 Headings. The Section headings herein are intended for reference and shall not by themselves determine the 

construction or interpretation of this Agreement.  

8.5 Governing Law; Venue. This Agreement shall be governed by and construed in accordance with the laws of
the  State  of  Texas.  Subject  in  all  respects  to  Section 7  generally  and  Section 7.3  in  particular,  any  dispute  arising  out  of  or 
relating to this Agreement may be brought in a court of competent jurisdiction located in Austin, Texas, and both of the parties to 
this Agreement irrevocably submit to the exclusive jurisdiction of such courts in any such dispute, waives any objection it may 
now or hereafter  have to venue  or  to convenience of forum, agrees that all claims in respect of the dispute shall be heard and 
determined only in any such court, and agrees not to bring any dispute arising out of or relating to this Agreement in any other 
court. The parties agree that either or both of them may file a copy of this paragraph with any court as written evidence of the 
knowing, voluntary and bargained agreement among the parties irrevocably to waive any objections to venue or to convenience 
of forum. Process in any dispute may be served on any party anywhere in the world.  

8.6  Severability.  Should any court  of  competent  jurisdiction  determine  that  any  provision  of this Agreement  is 
illegal or unenforceable to any extent, such provision shall be enforced to the extent permissible and all other provisions of this 
Agreement shall continue to be enforceable to the extent possible.  

8.7 Counterparts. This Agreement may be executed in one or more counterparts, all of which taken together shall 

constitute one and the same Agreement.  

8.8 Assignment. Neither this Agreement nor any duties or obligations hereunder may be assigned by either party 
without  the  other  party’s  prior  written  consent;  provided,  however,  that  Luminex  may  assign  this  Agreement  to  either  (i) a 
wholly-owned subsidiary of Luminex (provided, however, that such assignment shall not relieve Luminex of its  

Execution Version 

- 13 -

                                   
   
 
 
 
 
 
 
   
 
   
 
   
 
   
 
  
 
 
 
   
 
 
   
obligations  hereunder)  or  (ii) a  Person  acquiring  substantially  all  of  Luminex’s  assets  if  such  acquisition  would  constitute  a 
Change in Control.  

8.9 Withholding. All compensation and benefits payable to Executive hereunder shall be reduced by all federal, 

state, local and other withholdings and similar taxes and payments required by applicable law.  

Execution Version 

- 14 -

                                   
   
IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the day and year first above written.  

Execution Version 

LUMINEX CORPORATION 

By:  /s/ Patrick J. Balthrop  

EXECUTIVE 

/s/ Michael F. Pintek  
MICHAEL F. PINTEK 

- 15 -  

                                   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
EXHIBIT “A” 
GENERAL RELEASE AGREEMENT  

THIS GENERAL RELEASE AGREEMENT (this “Agreement”) dated as of the                                         day of               
                                               , [fill in effective date of termination pursuant to the Employment Agreement] (the “Effective 
Date”), is by and between Michael F. Pintek (“Executive”) and Luminex Corporation (“Luminex”).  

WHEREAS, Executive’s employment with Luminex has terminated pursuant to that certain Employment Agreement dated 

as of July 1, 2009 (the “Employment Agreement”);  

NOW, THEREFORE, in consideration of the foregoing premises and other good and valuable consideration, the receipt 

and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows:  

1. Termination of Employment. Executive and Luminex hereby agree that Executive’s employment with Luminex has 
terminated pursuant to Section  _____  [fill in applicable section] of the Employment Agreement effective as of the Effective 
Date.  To  the  extent  he  continues  to  hold  any  such  positions  or  directorships,  Executive  hereby  resigns  all  positions  and 
directorships he holds with Luminex and any and all of Luminex’s subsidiaries and affiliates.  

2. Release  by  Executive.  Executive,  on  his  own  behalf  and  on  behalf  of  the  Executive  Released  Parties  (defined 
below),  hereby  irrevocably  and  unconditionally  releases  and  forever  discharges  Luminex,  its  respective  subsidiaries  and other 
affiliated  and  their  respective  agents,  employees,  representatives,  officers,  directors,  stockholders,  trustees  and  attorneys,  past 
and present, and the heirs, successors and assigns of all of the foregoing (collectively, the “Released Parties”) from any and all 
debts, liabilities, claims, demands, actions or causes of action, suits, judgments or controversies of any kind whatsoever (except 
as set forth below) arising from Executive’s relationship (including without limitation as a stockholder) to, employment with or 
service  as  an  employee,  officer,  director,  or  manager  of  Luminex  or  its  subsidiaries  and  affiliates  (collectively,  the  “Claims”) 
against the Released Parties, that now exist or that may arise in the future out of any matter, transaction or event occurring prior 
to or on the Effective Date, including without limitation, any claims of breach of contract or for severance or other termination 
pay (except as set forth  in Section 4 below), or claims of harassment or discrimination (for example, on  the basis  of  age, sex, 
race, handicap, disability, religion, color or national origin) under any federal, state or local law, rule or regulation, including, but 
not limited to the Age Discrimination in Employment Act of 1967, 29 U.S.C. §621, et seq. Except as set forth below, Executive 
further  agrees  not  to  file  or  bring  any  claim,  suit,  civil  action,  complaint,  arbitration  or  administrative  action  (any  of  the 
foregoing, an “Action”) in any city, state or federal court or agency or arbitration tribunal with respect to any Claim against any 
of the Released Parties or (except as may be required by law) assist any other person or entity with any Action against any of the 
Released Parties. Notwithstanding anything to the contrary contained in this Agreement, Executive does not release any of the 
Released Parties and shall not be  

- 16 -  

                                   
   
prohibited  from  filing  or  bringing  an  Action  with  respect  to  any  right  Executive  otherwise  may  have  now  or  in  the  future  to 
(i) receive  distributions  or  dividends  made  in  respect  of  Luminex’s  capital  stock  or  (ii) be  indemnified  by  Luminex  under  the 
Certificate of Incorporation or Bylaws of Luminex (as the same are currently in effect), any resolution adopted by the Board of 
Directors  of  Luminex,  or  any  other  separate  written  agreement  or  instrument  requiring  Luminex  to  indemnify  Executive  or 
(iii) receive  workers’  compensation  claims  or  (iv) receive  Accrued  Obligations  (as  such  term  is  defined  in  the  Employment 
Agreement)  or  (v) receive  Severance  Compensation  (as  such  term  is  defined  in  the  Employment  Agreement)  or  (vi) stock, 
options,  and  other  equity-based  compensation  that  vested  prior  to  the  Effective  Date  or  that  vests  subsequent  to  the  Effective 
Date pursuant to the Employment Agreement or an applicable Luminex long-term incentive plan (which stock, options or other 
equity-based compensation shall be governed by the terms and provisions of the applicable written agreement(s) or instrument(s) 
and/or the applicable Luminex incentive plan) or (vii) vested benefits payable under retirement and other employee benefit plans 
covering Executive (which benefits shall be governed by the terms and provisions of the applicable plan).  

3. Release  by  Luminex.  Luminex,  on  its  own  behalf  and  on  behalf  of  the  Released  Parties,  hereby  irrevocably  and 
unconditionally  releases  and  forever  discharges  Executive  and  his  heirs,  successors  and  assigns  (collectively,  the  “Executive 
Released Parties”) from any and all Claims against the Executive Released Parties, that now exist or that may arise in the future. 
Except as set forth below, Luminex further agrees not to file or bring any Action in any city, state or federal court or agency or 
arbitration  tribunal  with  respect to any  Claim against  any  of the  Executive  Released  Parties  or (except as  may  be  required by 
law) assist any other person or entity with any Action against any of the Executive Released Parties. Notwithstanding anything to 
the  contrary  contained  in  this  Agreement,  Luminex  does  not  release  any  of  the  Executive  Released  Parties  and  shall  not  be 
prohibited  from  filing  or  bringing  an  Action  with  respect  to  (i) a  breach  by  Executive  after  the  Effective  Date  of  any  of 
Executive’s  obligations  under  the  Employment  Agreement  that  by  their  terms  survive  termination  of  the  Employment 
Agreement, including without limitation the provisions of Article 5 of the Employment Agreement, or (ii) in connection with any 
claim  for  indemnification  by  Executive,  any  obligation  or  burden  of  proof  applicable  to  Executive  that  is  a  condition  to 
Executive’s right to be indemnified by Luminex under the Certificate of Incorporation or Bylaws of Luminex (as the same are 
currently in effect),  any  resolution  adopted by the  Board of  Directors of Luminex,  or  any  other  separate  written agreement or 
instrument  requiring  Luminex  to  indemnify  Executive or  (iii) any  Claims  that  arise  out  of any criminal  or  fraudulent  activity, 
willful misconduct or gross negligence of Executive.  

4. Severance Compensation. In consideration of Executive’s execution of this Agreement, Executive shall be entitled 
to  receive  from  Luminex  the  Severance  Compensation  under  one  of  Section 4.1,  4.2  or  4.4  in  the  Employment  Agreement. 
Executive acknowledges that no other promise or agreements of any kind have been made to Executive or with Executive by any 
person  or  entity  whatsoever  to  cause  Executive  to  sign  this  Agreement.  Executive  further  acknowledges  and  agrees  that  the 
Severance  Compensation,  together  with  any  other  payments  or  benefits  that  may  be  due  under  the  terms  of  the  Employment 
Agreement,  shall  constitute  full  accord  and  satisfaction  of  all  obligations,  including  without  limitation  any  and  all  severance 
obligations,  in  connection  with  Executive’s  employment.  Executive  would  not  be  entitled  to  receive  the  Severance 
Compensation but for Executive’s execution of this Agreement.  

- 17 -

                                   
   
5. Disclaimer  of  Liability.  Executive  acknowledges  that  this  Agreement  shall  not  in  any  way  be  construed  as  an 
admission by Executive or any of the Released Parties of any wrongful or illegal act against the other or any other person, and 
that Executive and the Released Parties expressly disclaim any liability of any nature whatsoever arising from or related to the 
subject of this Agreement.  

6. COMPETENCY. EXECUTIVE ACKNOWLEDGES THE FOLLOWING:  

a. THAT  HE  FULLY  COMPREHENDS  AND  UNDERSTANDS  ALL  OF  THE  TERMS  OF  THIS  AGREEMENT 

AND THEIR LEGAL EFFECTS;  

b. THAT HE IS COMPETENT TO EXECUTE THIS AGREEMENT;  

c. THAT  IT  IS  EXECUTED  KNOWINGLY  AND  VOLUNTARILY  AND  WITHOUT  RELIANCE  UPON  ANY 

STATEMENT OR REPRESENTATION OF ANY RELEASED PARTY OR ITS REPRESENTATIVES;  

d. THAT HE HAS BEEN ADVISED IN WRITING TO CONSULT WITH AN ATTORNEY BEFORE EXECUTING 
THIS  AGREEMENT  AND  THAT  HE  HAS  HAD  THE  OPPORTUNITY  TO  CONSULT  WITH  AN  ATTORNEY  OF  HIS 
CHOICE REGARDING THIS AGREEMENT;  

e. THAT EXECUTIVE DOES NOT WAIVE RIGHTS OR CLAIMS THAT MAY ARISE AFTER THE DATE THIS 

AGREEMENT IS EXECUTED;  

f. THAT  EXECUTIVE  WAIVES  RIGHTS  OR  CLAIMS  UNDER  THIS  AGREEMENT  ONLY  IN  EXCHANGE 
FOR  CONSIDERATION  IN  ADDITION  TO  ANYTHING  OF  VALUE  TO  WHICH  THE  EXECUTIVE  WAS  ALREADY 
ENTITLED;  

g. [THAT  HE  HAS  BEEN  PROVIDED  THE  MATERIALS  REGARDING  THE  CLASS,  UNIT,  OR  GROUP  OF 
INDIVIDUALS ELIGIBLE FOR THIS COMPENSATION AND THE TIME LIMITS APPLICABLE TO SUCH PROGRAM;] 
[This clause to be included if required by or advisable under applicable law.]  

h. [THAT  HE  HAS  BEEN  PROVIDED  THE  JOB  TITLES  AND  AGES  OF  ALL  INDIVIDUALS  ELIGIBLE  OR 
SELECTED FOR THE PROGRAM AND THE AGES OF ALL INDIVIDUALS IN THE SAME JOB CLASSIFICATION OR 
ORGANIZATIONAL UNIT WHO ARE NOT ELIGIBLE OR SELECTED FOR THE PROGRAM;] [This clause to be included 
if required by or advisable under applicable law.]  

i. THAT  HE  HAS  HAD  A  PERIOD  OF  AT  LEAST  21  DAYS  [or  45 days,  if  required  by  or  advisable  under 

applicable law] WITHIN WHICH TO CONSIDER THIS AGREEMENT;  

j. THAT  FOR  A  PERIOD  OF  SEVEN  DAYS  FOLLOWING  THE  EXECUTION  OF  THIS  AGREEMENT, 
EXECUTIVE  MAY  REVOKE  THIS  AGREEMENT  AND  IT  SHALL  NOT  BECOME  EFFECTIVE  OR  ENFORCEABLE 
UNTIL THE SEVEN-DAY PERIOD HAS EXPIRED OR SUCH LATER DATE AS PROVIDED FOR HEREIN.  

- 18 -

  
   
7. Parties in Interest. This  Agreement is for the benefit of the Released Parties and shall be binding upon  Executive 

and his representatives and heirs.  

8. Governing Law. This  Agreement and  the  rights and obligations of Executive hereunder  shall  be governed  by  and 

construed and enforced in accordance with the substantive laws of the State of Texas.  

9. Amendment. This Agreement may not be clarified, modified, changed or amended except in writing and signed by 

Executive and Luminex or a successor-in-interest of Luminex.  

10. Non-disparagement. Executive agrees that he will refrain from speaking ill of or making any disparaging comment 
about Luminex or Luminex’s management, other employees or contractors, following the termination of his employment except 
as may be necessary or advisable, in the reasonable judgment of Executive, to enforce his rights under this Agreement, enforce 
claims arising after the Effective Date and not released in this Agreement, or defend a legal action brought against Executive by 
any of the Released Party.  Luminex agrees that it will  refrain from speaking  ill  of  or  making any disparaging comment  about 
Executive following the termination of his employment except as may be necessary or advisable, in the reasonable judgment of 
Luminex,  to  (i)  to  enforce  its  rights  under  the  Employment  Agreement  or  this  Agreement  not  released  in  this  Agreement  or 
(ii) defend a legal action brought against any of the Released Parties by Executive or (iii) comply with applicable securities laws 
or protect Luminex from potential liability.  

11. Enforcement of Laws. Nothing in this Agreement affects the rights and responsibilities of the Equal Employment 
Opportunity Commission (the “Commission”) to enforce the anti-discrimination laws, and this waiver does not affect Executive’s 
right to file a charge or participate in an investigation or proceeding with the Commission. However, Executive waives any rights 
or claims, known or unknown, to participate in any recovery under any proceeding or investigation by the Commission or any 
state or local commission concerned with the enforcement of anti-discrimination laws.  

12. Severability.  If  any  provision  of  this  Agreement  is  held  to  be  illegal,  invalid  or  unenforceable  under  present  or 
future laws, such provision shall be fully severable and this Agreement shall be construed and enforced as if such illegal, invalid 
or  unenforceable  provision  never  comprised  a  part  hereof;  and  the  remaining  provisions  hereof  shall  remain  in  full  force  and 
effect and shall not be affected by the illegal, invalid or unenforceable provision, and there shall be added automatically as part 
of this Agreement a provision as similar in its terms to such illegal, invalid or unenforceable provision as may be possible and be 
legal, valid and enforceable.  

- 19 -

                                   
   
IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the day and year first above written. 

LUMINEX CORPORATION 

By:   

EXECUTIVE 

Michael F. Pintek, individually 

- 20 -

                                   
   
 
 
  
 
 
 
 
 
 
     
 
 
 
 
 
 
 
EXHIBIT 21.1  

LIST OF SUBSIDIARIES  

Luminex International, Inc., a Delaware corporation 
Luminex B.V., a Dutch Private Limited Liability Company 
Luminex Molecular Diagnostics, Inc., an Ontario, Canada corporation 
Luminex Trading (Shanghai) Co., Ltd., a Chinese Foreign Investment Company 
Luminex Japan Corporation Ltd., a Japanese KK  

                                   
 
Exhibit 23.1

Consent of Independent Registered Public Accounting Firm  

We consent to the incorporation by reference in the Registration Statement (Form S-8 No. 333-141042) pertaining to the Tm 
Bioscience Corporation Share Option Plan, in the Registration Statement (Form S-8 No. 333-134450) pertaining to the Luminex 
Corporation 2006 Equity Incentive Plan and the Luminex Corporation 2006 Management Stock Purchase Plan, in the 
Registration Statement (Form S-8 No. 333-46686) pertaining to the 2000 Long-Term Incentive Plan of Luminex Corporation, in 
the Registration Statement (Form S-8 No. 333-87918) pertaining to the 2001 Broad-Based Stock Option Plan of Luminex 
Corporation and in the Registration Statement (Form S-8 No. 333-118772) pertaining to the Balthrop Non-Qualified Stock 
Option Agreement of Luminex Corporation, in the Registration Statement (Form S-8 No. 333-159382) pertaining to the 
Amended and Restated 2006 Equity Incentive Plan and in the Registration Statement (Form S-3 No. 333-151691) of our reports 
dated February 25, 2010, with respect to the consolidated financial statements of Luminex Corporation, and the effectiveness of 
internal control over financial reporting of Luminex Corporation, included in this Annual Report (Form 10-K) for the year ended 
December 31, 2009.  

/s/ Ernst & Young LLP  

Austin, Texas  
February 25, 2010  

                                   
 
Exhibit 31.1 

I, Patrick J. Balthrop, certify that:  

1. I have reviewed this report on Form 10-K of Luminex Corporation;  

CERTIFICATIONS  

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material 
fact  necessary  to  make  the  statements  made,  in  light  of  the  circumstances  under  which  such  statements  were  made,  not 
misleading with respect to the period covered by this report;  

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in 
all  material  respects  the  financial  condition,  results  of  operations  and  cash  flows  of  the  registrant  as  of,  and  for,  the  periods 
presented in this report;  

4. The  registrant’s other  certifying officers  and  I are  responsible for  establishing and  maintaining  disclosure controls and 
procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined 
in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:  

a)  Designed  such  disclosure  controls  and  procedures,  or  caused  such  disclosure  controls  and  procedures  to  be  designed 
under  our  supervision,  to  ensure  that  material  information  relating  to  the  registrant,  including  its  consolidated  subsidiaries,  is 
made known to us by others within those entities, particularly during the period in which this report is being prepared;  

b)  Designed  such  internal  control  over  financial  reporting,  or  caused  such  internal  control  over  financial  reporting  to  be 
designed  under  our  supervision,  to  provide  reasonable  assurance  regarding  the  reliability  of  financial  reporting  and  the 
preparation of financial statements for external purposes in accordance with generally accepted accounting principles;  

c)  Evaluated  the  effectiveness  of  the  registrant’s  disclosure  controls  and  procedures  and  presented  in  this  report  our 
conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report 
based on such evaluation; and  

d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the 
registrant’s most  recent fiscal quarter  (the registrant’s fourth  fiscal  quarter in the  case of  an  annual report) that  has  materially 
affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and  

5. The  registrant’s  other  certifying  officers  and  I  have  disclosed,  based  on  our  most  recent  evaluation  of  internal  control 
over  financial  reporting,  to  the  registrant’s  auditors  and  the  audit  committee  of  the  registrant’s  board  of  directors  (or  persons 
performing the equivalent functions):  

a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting 
which  are  reasonably  likely  to  adversely  affect  the  registrant’s  ability  to  record,  process,  summarize  and  report  financial 
information; and  

b)  Any  fraud,  whether  or  not  material,  that  involves  management  or  other  employees  who  have  a  significant  role  in  the 

registrant’s internal control over financial reporting.  

Date: February 25, 2010  

By:  /s/ Patrick J. Balthrop  
Patrick J. Balthrop 
President and Chief Executive Officer 

                                   
   
 
 
 
 
 
 
 
 
Exhibit 31.2 

I, Harriss T. Currie, certify that:  

1. I have reviewed this report on Form 10-K of Luminex Corporation;  

CERTIFICATIONS  

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material 
fact  necessary  to  make  the  statements  made,  in  light  of  the  circumstances  under  which  such  statements  were  made,  not 
misleading with respect to the period covered by this report;  

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in 
all  material  respects  the  financial  condition,  results  of  operations  and  cash  flows  of  the  registrant  as  of,  and  for,  the  periods 
presented in this report;  

4. The  registrant’s other  certifying officers  and  I are  responsible for  establishing and  maintaining  disclosure controls and 
procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined 
in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:  

a)  Designed  such  disclosure  controls  and  procedures,  or  caused  such  disclosure  controls  and  procedures  to  be  designed 
under  our  supervision,  to  ensure  that  material  information  relating  to  the  registrant,  including  its  consolidated  subsidiaries,  is 
made known to us by others within those entities, particularly during the period in which this report is being prepared;  

b)  Designed  such  internal  control  over  financial  reporting,  or  caused  such  internal  control  over  financial  reporting  to  be 
designed  under  our  supervision,  to  provide  reasonable  assurance  regarding  the  reliability  of  financial  reporting  and  the 
preparation of financial statements for external purposes in accordance with generally accepted accounting principles;  

c)  Evaluated  the  effectiveness  of  the  registrant’s  disclosure  controls  and  procedures  and  presented  in  this  report  our 
conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report 
based on such evaluation; and  

d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the 
registrant’s most  recent fiscal quarter  (the registrant’s fourth  fiscal  quarter in the  case of  an  annual report) that  has  materially 
affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and  

5. The  registrant’s  other  certifying  officers  and  I  have  disclosed,  based  on  our  most  recent  evaluation  of  internal  control 
over  financial  reporting,  to  the  registrant’s  auditors  and  the  audit  committee  of  the  registrant’s  board  of  directors  (or  persons 
performing the equivalent functions):  

a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting 
which  are  reasonably  likely  to  adversely  affect  the  registrant’s  ability  to  record,  process,  summarize  and  report  financial 
information; and  

b)  Any  fraud,  whether  or  not  material,  that  involves  management  or  other  employees  who  have  a  significant  role  in  the 

registrant’s internal control over financial reporting.  

Date: February 25, 2010  

By:  /s/ Harriss T. Currie  
Harriss T. Currie 
Vice President - Finance 
Chief Financial Officer 
Treasurer 

                                   
   
 
 
 
 
 
 
 
 
 
CERTIFICATION PURSUANT TO 
18 U.S.C. SECTION 1350, 
AS ADOPTED PURSUANT TO 
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002  

Exhibit 32.1

In  connection  with  the  Annual  Report  of  Luminex  Corporation  (the  “Company”)  on  Form  10-K  for  the  period  ended 
December 31,  2009,  as  filed  with  the  Securities  and  Exchange  Commission  on  the  date  hereof  (the  “Report”),  I,  Patrick  J. 
Balthrop, President and Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. §1350, as adopted pursuant to 
§906 of the Sarbanes-Oxley Act of 2002, that:  

(1) The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and  

(2) The  information  contained in  the Report  fairly presents,  in all material respects, the financial  condition and  results of 

operations of the Company.  

/s/ PATRICK J. BALTHROP  
Patrick J. Balthrop 
President and Chief Executive Officer  
February 25, 2010

                                   
   
     
 
 
 
 
 
 
CERTIFICATION PURSUANT TO 
18 U.S.C. SECTION 1350, 
AS ADOPTED PURSUANT TO 
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002  

Exhibit 32.2

In  connection  with  the  Annual  Report  of  Luminex  Corporation  (the  “Company”)  on  Form  10-K  for  the  period  ended 
December 31,  2009,  as  filed  with  the  Securities  and  Exchange  Commission  on  the  date  hereof  (the  “Report”),  I,  Harriss  T. 
Currie, Vice President — Finance, Chief Financial Officer and Treasurer of the Company, certify, pursuant to 18 U.S.C. §1350, 
as adopted pursuant to §906 of the Sarbanes-Oxley Act of 2002, that:  

(1) The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and  

(2) The  information  contained in  the Report  fairly presents,  in all material respects, the financial  condition and  results of 

operations of the Company.  

/s/ HARRISS T. CURRIE  
Harriss T. Currie 
Vice President - Finance 
Chief Financial Officer 
Treasurer  
February 25, 2010