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NeoGenomics, Inc.

neo · NASDAQ Healthcare
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Employees 2200
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FY2018 Annual Report · NeoGenomics, Inc.
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM 10-K/A
Amendment No. 1

☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the fiscal year ended  December 31, 2018 

or

For the transition period from _________ to __________                    

Commission File Number: 001-35756

NEOGENOMICS, INC.
(Exact name of registrant as specified in its charter)

(State or other jurisdiction of incorporation or organization)

(IRS Employer Identification No.)

Nevada

74-2897368

12701 Commonwealth Drive, Suite 9, Fort Myers, FL 33913
(Address of principal executive offices, Zip code)
(239) 768-0600
(Registrant’s telephone number, including area code)

Securities registered pursuant to Section 12(b) of the Act:

Common Stock, par value $0.001 per share

Name of each exchange on which registered:

NASDAQ Capital Market

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act.    Yes   ☐     No   ☒

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15(d) of the Act.    Yes   ☐     No   ☒

Securities registered pursuant to Section 12(g) of the Act: Common Stock par value $0.001 per share

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for
such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.    Yes   ☒     No   ☐

Indicate  by  check  mark  whether  the  registrant  has  submitted  electronically  every  Interactive  Data  File  required  to  be  submitted  pursuant  to  Rule  405  of  Regulation  S-T  (§232.405  of  this
chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).    Yes   ☒     No   ☐

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K (§229.405 of this chapter) is not contained herein, and will not be contained, to the best of
registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K.   ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. See the
definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer

Non-accelerated filer

☑  
☐

Accelerated filer

Smaller Reporting Company

Emerging Growth Company

☐

☐

☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting
standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act):     ☐   Yes     ☒   No

As of June 30, 2018, the aggregate market value of the registrant’s common stock held by non-affiliates of the registrant was approximately  $790.6 million, based on the closing price of the
registrant’s common stock of $13.11 per share on June 30, 2018.

The number of shares outstanding of the registrant’s Common Stock, par value $0.001 per share, as of February 22, 2019: 94,565,844. 

DOCUMENTS INCORPORATED BY REFERENCE

Portions of the registrant’s Proxy Statement for its 2019 Annual Meeting of Stockholders are incorporated by reference into Part III of this Annual Report on Form 10-K.

 
 
 
 
 
 
NEOGENOMICS, INC.

EXPLANATORY NOTE

This Amendment No. 1 on Form 10-K/A (the “Amendment”) amends NeoGenomics, Inc.’s Annual Report on Form 10-K for the fiscal year ended December 31, 2018 (the
“Form 10-K”), as filed with the Securities and Exchange Commission on February 26, 2019, and is being filed solely to correct an administrative error of a missing signature of
a director on the Form 10-K.

Pursuant to Rule 12b-15 promulgated under the Securities Exchange Act of 1934, as amended, we have repeated the entire text of the Form 10-K in this Amendment. However,
there have been no changes to the text other than the change stated in the immediately preceding paragraph.

This Amendment includes new certifications by our Principal Executive Officer and Principal Financial Officer pursuant to Sections 302 and 906 of the Sarbanes-Oxley Act of
2002 as exhibits 31.1, 31.2 and 32.1 hereto.

Except as expressly set forth above, this Amendment does not, and does not purport to, amend, update or restate the information in any other item of the Form 10-K or reflect
any events that have occurred after the filing of the original Form 10-K.

NEOGENOMICS, INC.

FORM 10-K ANNUAL REPORT
For the Fiscal Year Ended December 31, 2018 

Table of Contents

PART I
Item 1.
Item 1A.
Item 1B.
Item 2.
Item 3.
Item 4.

PART II
Item 5.
Item 6.
Item 7.
Item 7A.
Item 8.
Item 9.
Item 9A.
Item 9B.

PART III
Item 10.
Item 11.
Item 12.
Item 13.
Item 14.

PART IV
Item 15.

SIGNATURES

  Business
  Risk Factors
  Unresolved Staff Comments
  Properties
  Legal Proceedings
  Mine Safety Disclosures

  Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities
  Selected Financial Data
  Management’s Discussion and Analysis of Financial Condition and Results of Operations
  Quantitative and Qualitative Disclosures About Market Risk
  Financial Statements and Supplementary Data
  Changes in and Disagreements With Accountants on Accounting and Financial Disclosure
  Controls and Procedures
  Other Information

  Directors, Executive Officers and Corporate Governance
  Executive Compensation
  Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters
  Certain Relationships and Related Transactions, and Director Independence
  Principal Accounting Fees and Services

  Exhibits and Financial Statement Schedules

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The “NeoGenomics”,“Genoptix” and “Clarient” names and logos have been trademarked with the United States Patent and Trademark Office. We have also trademarked or
have  applications  pending  for  the  brand  names  NeoFISH,  NeoFLOW,  NeoSITE,  NeoArray,  NeoTYPE,  NeoSCORE,  NeoLAB,  NeoLINK,  MultiOmyx,  CO MPASS,  and
CHART. We have also trademarked the marketing slogans, “When time matters and results count” and “Time matters, results count.”  Any other trademarks, registered marks
and trade names appearing in this annual report on Form 10-K are the property of their respective holders.

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NEOGENOMICS, INC.

PART I

FORWARD-LOOKING STATEMENTS

The information in this Annual Report on Form 10-K contains “forward-looking statements” and information within the meaning of Section 27A of the Securities Act of 1933,
as amended, or the “Securities Act”, and Section 21E of the Securities Exchange Act of 1934, as amended, or the “Exchange Act”, which are subject to the “safe harbor” created
by  those  sections.  These  forward-looking  statements  include,  but  are  not  limited  to,  statements  concerning  our  strategy,  future  operations,  future  financial  position,  future
revenues,  changing  reimbursement  levels  from  government  payers  and  private  insurers,  projected  costs,  prospects  and  plans  and  objectives  of  management.  The  words
“anticipates,”  “believes,”  “estimates,”  “expects,”  “intends,”  “may,”  “plans,”  “projects,”  “will,”  “would”  and  similar  expressions  are  intended  to  identify  forward-looking
statements,  although  not  all  forward-looking  statements  contain  these  identifying  words.  We  may  not  actually  achieve  the  plans,  intentions  or  expectations  disclosed  in  our
forward-looking statements and you should not place undue reliance on our forward-looking statements. These forward-looking statements involve known and unknown risks
and  uncertainties  that  could  cause  our  actual  results,  performance  or  achievements  to  differ  materially  from  those  expressed  or  implied  by  the  forward-looking  statements,
including, without limitation, the risks set forth in Part I, Item 1A, “Risk Factors” in this Annual Report on Form 10-K and in our other filings with the Securities and Exchange
Commission, or “SEC”.

Forward-looking statements include, but are not limited to, statements about:

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Our ability to respond to rapid scientific change;

The risk of liability in conducting clinical trials and the sufficiency of our insurance to cover such claims;

Our ability to implement our business strategy;

The expected reimbursement levels from governmental payers and private insurers and proposed changes to those levels;

The application, to our business and the services we provide, of existing laws, rules and regulations, including without limitation, Medicare laws, anti-kickback laws,
Health  Insurance  Portability  and Accountability Act  of  1996  regulations,  state  medical  privacy  laws,  federal  and  state  false  claims  laws  and  corporate  practice  of
medicine laws;

Regulatory developments in the United States including downward pressure on health care reimbursement;

Our ability to maintain our license under the Clinical Laboratory Improvement Amendments of 1988 (“CLIA”);

Food and Drug Administration, or FDA regulation of Laboratory Developed Tests (“LDTs”);

Failure to timely or accurately bill for our services;

Our ability to expand our operations and increase our market share;

Our ability to expand our service offerings by adding new testing capabilities;

Our ability to meet our future capital requirements;

The impact of internalization of testing by customers;

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Our ability to manage our indebtedness;

Our ability to protect our intellectual property from infringement;

Our ability to successfully integrate Genoptix into NeoGenomics including consolidating systems and facilities;

Our ability to integrate future acquisitions and costs related to such acquisitions;

The effects of seasonality on our business;

Our ability to maintain service levels and compete with other diagnostic laboratories;

Our ability to hire and retain sufficient managerial, sales, clinical and other personnel to meet our needs;

Our ability to successfully scale our business, including expanding our facilities, our backup systems and infrastructure;

Our handling, storage and disposal of biological and hazardous materials;

The accuracy of our estimates regarding reimbursement, expenses, future revenues and capital requirements and

Our ability to manage expenses and risks associated with international operations, including anti-corruption and trade sanction laws and other regulations, and economic,
political, legal and other operational risks associated with foreign jurisdictions.

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Any  forward-looking  statement  speaks  only  as  of  the  date  on  which  such  statement  is  made,  and  the  Company  undertakes  no  obligation  to  update  any  forward-looking
statement  or  statements  to  reflect  events  or  circumstances  after  the  date  on  which  such  statement  is  made  or  to  reflect  the  occurrence  of  unanticipated  events.  New  factors
emerge from time to time and it is not possible for management to predict all of such factors, nor can it assess the impact of each such factor on the business or the extent to
which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements.

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ITEM 1. BUSINESS

NeoGenomics, Inc., a Nevada corporation (referred to individually as the “Parent Company” or collectively with its subsidiaries as “NeoGenomics”, “we”, “us”, “our” or the
“Company” in this Annual Report) is the registrant for SEC reporting purposes. Our common stock is listed on the NASDAQ Capital Market under the symbol “NEO”.

Overview

We operate a network of cancer-focused genetic testing laboratories in the United States as well as a laboratories in Switzerland and Singapore.  Our mission is to improve
patient care through exceptional genetic and molecular testing services. Our vision is to become the World’s leading cancer testing and information company by delivering
uncompromising quality, exceptional service and innovative solutions.

As  of  December  31,  2018,  the  Company  has  laboratory  locations  in  Ft.  Myers  and  Tampa,  Florida; Aliso  Viejo,  Carlsbad  and  Fresno,  California;  Houston,  Texas; Atlanta,
Georgia; Nashville, Tennessee; Rolle, Switzerland, and Singapore and currently offers the following types of genetic and molecular testing services:

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b.

c.

d.

e.

f.

Cytogenetics - the study of normal and abnormal chromosomes and their relationship to disease. It involves looking at the chromosome structure to identify
changes  from  patterns  seen  in  normal  chromosomes.  Cytogenetic  studies  are  often  utilized  to  answer  diagnostic,  prognostic  and  predictive  questions  in  the
treatment of hematological malignancies.

Fluorescence  In-Situ  Hybridization  (“FISH”)  -  a  branch  of  cancer  genetics  that  focuses  on  detecting  and  locating  the  presence  or  absence  of  specific  DNA
sequences  and  genes  on  chromosomes.  FISH  helps  bridge  abnormality  detection  between  the  chromosomal  and  DNA  sequence  levels.  The  technique  uses
fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy is
used to visualize the fluorescent probes bound to the chromosomes. FISH can be used to help identify a number of gene alternations, such as amplification,
deletions, and translocations.

Flow cytometry - a rapid way to measure the characteristics of cell populations. Cells from peripheral blood, bone marrow aspirate, lymph nodes, and other
areas are labeled with selective fluorescent antibodies and analyzed as they flow in a fluid stream through a beam of light. The properties measured in these
antibodies include the relative size, relative granularity or internal complexity, and relative fluorescence intensity. These fluorescent antibodies bind to specific
cell surface antigens and are used to identify malignant cell populations. Flow cytometry is typically performed in diagnosing a wide variety of leukemia and
lymphoma neoplasms. Flow cytometry is also used to monitor patients through therapy to determine whether the disease burden is increasing or decreasing,
otherwise known as minimal residual disease monitoring.

Immunohistochemistry  (“IHC”)  and  Digital  Imaging  –  Refers  to  the  process  of  localizing  proteins  in  cells  of  a  tissue  section  and  relies  on  the  principle  of
antibodies binding specifically to antigens in biological tissues. IHC is widely used in the diagnosis of abnormal cells such as those found in cancerous tumors.
Specific surface cytoplasmic or nuclear markers are characteristic of cellular events such as proliferation or cell death (apoptosis). IHC is also widely used to
understand the distribution and localization of differentially expressed proteins.  Digital imaging allows clients to see and utilize scanned slides and perform
quantitative analysis for certain stains.  Scanned slides are received online in real time and can be previewed often a full day before the glass slides can be
shipped back to clients.

Molecular testing - a rapidly growing cancer diagnostic tool focusing on the analysis of DNA and RNA, as well as the structure and function of genes at the
molecular level. Molecular testing employs multiple technologies including DNA fragment length analysis, real-time polymerase chain reaction (“RT-PCR”)
RNA analysis, bi-directional Sanger sequencing analysis, and Next-Generation Sequencing (“NGS”).

Pathology  consultation  -  services  provided  for  clients  in  which  our  pathologists  review  surgical  samples  on  a  consultative  basis.  NeoGenomics  expert
pathologists often assist our client pathologists on their most difficult and complex cases.

Operating Segments

We have two primary types of customers, Clinical and Pharma.  Our Clinical customers include community based pathology practices, oncology groups, hospitals and academic
centers.  Our Pharma customers include pharmaceutical companies to whom we provide testing and other services to support their studies and clinical trials.

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In 2018, our Clinical Services segment accounted for 87% of consolidated revenues and our Pharma Services segment accounted for 13% of our consolidated revenues.  For
further financial information about these segments, see Note R to our Consolidated Financial Statements included in this Annual Report.

Clinical Services Segment

The clinical cancer testing services we offer to community-based pathologists are designed to be a natural extension of, and complementary to, the services that they perform
within their own practices. We believe our relationship as a non-competitive partner to community-based pathology practices, hospital pathology labs and academic centers
empowers them to expand their breadth of testing and provide a menu of services that matches or exceeds the level of service found in any center of excellence around the
world. Community-based pathology practices and hospital pathology labs may order certain testing services on a technical component only (“TC” or “tech-only”) basis, which
allows them to participate in the diagnostic process by performing the professional component (“PC”) interpretation services without having to hire laboratory technologists or
purchase the sophisticated equipment needed to perform the technical component of the tests. We also support our pathology clients with interpretation and consultative services
using our own specialized team of pathologists for difficult or complex cases and provide overflow interpretation services when requested by clients.

In addition, we may directly serve oncology, dermatology, urology and other clinician practices that prefer to have a direct relationship with a laboratory for cancer-related
genetic and molecular testing services. We typically service these types of clients with a comprehensive service offering where we perform both the technical and professional
components of the tests ordered. In certain instances larger clinician practices have begun to internalize pathology interpretation services, and our “tech-only” service offering
allows these larger clinician practices to also participate in the diagnostic process by performing the PC interpretation services on TC testing performed by NeoGenomics.  In
these instances NeoGenomics will typically provide all of the more complex, molecular testing services.

Pharma Services Segment

Our Pharma Services segment supports pharmaceutical firms in their drug development programs by supporting various clinical trials and research.  This portion of our business
often involves working with the pharmaceutical firms (sponsors) on study design as well as performing the required testing.  Our medical team often advises the sponsor and
works closely with them as specimens are received from the enrolled sites.  We also work on developing tests that will be used as part of a companion diagnostic to determine
patients’ response to a particular drug.  As studies unfold, our clinical trials team reports the data and often provides key analysis and insights back to the sponsors.  

Our Pharma Services segment provides comprehensive testing services in support of our pharmaceutical clients’ oncology programs from discovery to commercialization.  In
biomarker  discovery,  our  aim  is  to  help  our  customers  discover  the  right  content.    We  help  our  customers  develop  a  biomarker  hypothesis  by  recommending  an  optimal
platform for molecular screening and backing our discovery tools with the informatics to capture meaningful data.  In other pre and non-clinical work, we can use our platforms
to characterize markers of interest.  Moving from discovery to development, we help our customers refine their biomarker strategy and, if applicable, develop a companion
diagnostic pathway using the optimal technology for large-scale clinical trial testing.

Whether serving as the single contract research organization or partnering with one, our Pharma Services team provides significant technical expertise, working closely with our
customers to support each stage of clinical trial development.  Each trial we support comes with rapid turnaround time, dedicated project management and quality assurance
oversight. We have experience in supporting submissions to the Federal Drug Administration (“FDA”) for companion diagnostics and our Pharma Services strategy is focused
on helping bring more effective oncology treatments to market through providing world class laboratory services in oncology to key pharmaceutical companies in the industry.

Our Pharma Services revenue consists of three revenue streams:
Clinical trials and research;
Validation laboratory services; and
Data services

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Markets

The medical testing laboratory market can be broken down into three primary markets:

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Clinical Pathology testing;
Anatomic Pathology testing; and
Genetic and Molecular testing

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Clinical Pathology testing covers high volume, highly automated, lower complexity tests on easily procured specimens such as blood and urine. Clinical lab tests often involve
testing of a less urgent nature, for example, cholesterol testing and testing associated with routine physical exams.

Anatomic Pathology testing involves evaluation of tissue, as in surgical pathology, or cells as in cytopathology. The most widely performed Anatomic Pathology procedures
include the preparation and interpretation of pap smears, skin biopsies, and tissue biopsies.

Genetic and molecular testing typically involves analyzing chromosomes, genes, proteins and/or DNA/RNA sequences for abnormalities. Genetic and molecular testing requires
highly specialized equipment and credentialed individuals (typically M.D. or Ph.D. level) to certify results and typically yields the highest reimbursement levels of the three
market segments.

NeoGenomics  operates  primarily  in  the  genetic  and  molecular  testing  market.  We  also  act  as  a  reference  laboratory  supplying  anatomic  pathology  testing.  NeoGenomics
typically does not compete in the clinical pathology testing market.  

The field of cancer genetics is evolving rapidly and new tests are being developed at an accelerated pace. Based on medical and scientific discoveries over the last decade,
cancer testing falls into one of three categories: diagnostic testing, prognostic testing and predictive testing. Of the three, the fastest growing area is predictive testing, which is
utilized by clinicians to predict a patient’s response to the various treatment options in order to deliver “personalized or precision medicine” that is optimized to that patient’s
particular circumstances. Personalized or precision medicine allows clinicians to know if a patient will or will not respond to certain medications like Herceptin, Keytruda and
Opdivo. This saves the healthcare system money by ensuring that expensive cancer drugs are only given to those who will benefit from them. This type of testing improves
patient care and potentially saves lives by identifying optimized therapies much more rapidly than what was possible in previous years.

The  United  States  market  for  genetic  and  molecular  testing  is  divided  among  numerous  laboratories.  Many  of  these  laboratories  are  attached  to  academic  institutions  and
primarily provide clinical services to their affiliated university hospitals and associated physicians.

We believe several key factors are influencing the rapid growth in the market for cancer testing: (i) every year, more and more genes and genomic pathways are implicated in
the development and/or clinical course of cancer; (ii) cancer is primarily a disease of the elderly - one in four senior citizens is likely to develop some form of cancer during the
rest of their lifetime once they turn sixty, and now that the baby boomer generation has started to reach this age range, the incidence rates of cancer are rising; (iii) increasingly,
new drugs are being targeted to certain cancer subtypes and pathways which require companion diagnostic testing; (iv) patient and payer awareness of the value of genetic and
molecular testing; (v) decreases in the cost of performing genetic and molecular testing; (vi) increased coverage from third party payers and Medicare for such testing; and
(vii) the health insurance coverage to uninsured Americans under the Patient Protection and Affordable Care Act as amended by the Health Care and Education Reconciliation
Act, each enacted in March 2010. These factors have driven significant growth in the market for this type of testing.

2019 Focus Areas:

We are committed to being an innovative leader in our industry.  Over the past year, we have grown our business organically as well as through the acquisition of Genoptix in
December of 2018. We have continued to expand internationally with the opening of a laboratory in Singapore.  Our plans for 2019 include initiatives to drive profitable growth
while successfully integrating Genoptix and maintaining exceptional service levels. We expect these initiatives to continue to position our Company to be the world’s leading
cancer testing and information company.

Strengthen Our World-Class Culture  

Our belief is that a culture of motivated and engaged employees will deliver superior service to our clients.  We are focused on continuing to strengthen our culture by actively
seeking  feedback  and  ideas  from  employees  on  ways  to  innovate  and  grow  our  business. We  will  foster  employee  engagement  through  collaborative  forums,  frequent  team
dialogue and programs to reward teams for exceptional performance.

Enhancing our culture to closely align with the values of our Company is a key priority.  We will focus on creating a unified culture as we bring Genoptix and NeoGenomics
employees together to become one team. We will create mentoring and training opportunities to enhance and capitalize on the talent within our Company.  We believe these
initiatives will foster a culture of accountability and empowerment.  We also believe these initiatives are necessary to ensure the success of our Company.    

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Communication is a key element in our high performance culture.  Through effective communication we facilitate our employees’ understanding of our Company’s priorities
and how they contribute to the Company’s overall objectives.  We believe our employee retention rate is above average for the laboratory industry and continuing to strengthen
our culture will enable us to continually recruit and retain talented employees.    

Provide Uncompromising Quality

Maintaining the highest quality laboratory operations and service levels has enabled us to consistently grow our business.  We are continuously looking for ways to improve
quality and, in integrating Genoptix and NeoGenomics, we will identify best practices and implement changes to streamline processes across the organization. We are keenly
focused on increasing automation and looking for solutions that will maintain quality while improving efficiency in operations.

We plan to continue to grow a culture of quality through company-wide leadership, coaching and employee engagement initiatives.  Through training, we aim to empower our
employees to understand the importance of quality and how to ensure quality in their respective function.  We will implement initiatives to significantly improve the Corrective
and Preventative Actions (“CAPA”) process to ensure FDA readiness and will challenge employees to identify quality issues and find solutions.

We have been successful in retaining clients while also gaining market share. As we integrate Genoptix, our goal is to ensure that we maintain the highest quality operation.

Pursue Exceptional Service and Growth

Our  plans  for  2019  include  initiatives  to  continue  to  drive  profitable  growth. We  will  continue  to  pursue  market  share  gains  by  providing  high  complexity,  cancer-related
laboratory testing services to hospitals, community-based pathology practices, academic centers, clinicians, and pharmaceutical companies.

Our  laboratory  teams  will  focus  on  service  by  improving  the  customer  experience. This  will  be  accomplished  through  the  development  and  launch  of  innovative  assays,
informatics products and companion diagnostics as well as enhancements to our educational programs. We expect this to result in increased product and process understanding,
increased ability to gain market share as well as enabling us to maintain our high levels of client retention.

We will work to maintain our broad and innovative test menu of molecular, immunohistochemistry, and other testing, which has helped make us a “one stop shop” for many
clients who value that all of their testing can be sent to one laboratory. We believe successfully integrating Genoptix and NeoGenomics' operations will allow us to increase
efficiency and reduce cost per test. We will continue to look for growth opportunities through mergers and/or acquisitions and are focused on strategic opportunities that would
be complementary to our menu of services and would increase our earnings and cash flow in the short to medium time frame. 

Competitive Strengths

In addition to the competitive strengths discussed below, the Company believes that its superior testing technologies and instrumentation, laboratory information system, client
education programs and broad domestic and growing international presence also differentiate NeoGenomics from its competitors.

Turnaround Times

We  strive  to  provide  industry  leading  turnaround  times  for  test  results  to  our  clients  nationwide,  both  in  the  Clinical  Services  and  Pharma  Services  segments. By  providing
information to our clients in a rapid manner, physicians can begin treating their patients as soon as possible. Our consistent timeliness of results in our Clinical Services segment
is a competitive strength and a driver of additional testing requests by our referring physicians. Rapid turnaround times allow for the performance of other adjunctive tests within
an acceptable diagnosis window in order to augment or confirm results and more fully inform treatment options. Additionally, we believe that our rapid turnaround time on
testing and our project milestones are a key differentiator in the Pharma Services segment.

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World-class Medical and Scientific Team

Our team of medical professionals and Ph.Ds. are specialists in the field of genetics, oncology and pathology.  As of December 31, 2018, we employed or contracted with over
80 M.D.s and Ph.Ds.  We have many nationally and world-renowned pathologists on staff, which is a key differentiator from many smaller laboratories.  Our clinical customers
look to our staff and their expertise and they often call our medical team on challenging cases.  For our Pharma Services segment, many sponsors work with our medical team
on their study design and on the interpretation of results from the studies.  Again, our medical team is a key differentiator as we have a depth of medical expertise that many
other laboratories cannot offer to Pharmaceutical companies.

Innovative Service Offerings

We believe we currently have the most extensive menu of tech-only FISH services in the country as well as extensive and advanced tech-only flow cytometry and IHC testing
services. These types of testing services allow the professional interpretation component of a test to be performed and billed separately by our physician clients. Our tech-only
services  are  designed  to  give  pathologists  the  option  to  choose,  on  a  case  by  case  basis,  whether  they  want  to  order  just  the  technical  information  and  images  relating  to  a
specific test so they can perform the professional interpretation, or order “global” services and receive a comprehensive test report which includes a NeoGenomics pathologist’s
interpretation of the test results. Our clients appreciate the flexibility to access NeoGenomics’ medical staff for difficult or complex cases or when they are otherwise unavailable
to perform professional interpretations.

We offer a comprehensive suite of technical and interpretation services, to meet the needs of those clients who are not credentialed and trained in interpreting genetic tests and
who require pathology specialists to interpret the testing results for them. In our global service offerings, our lab performs the technical component of the tests and our M.D.s
and Ph.Ds. provide the service of interpreting the results of those tests. Our professional staff is also available for post-test consultative services. Clients using our global service
offering rely on the expertise of our medical team to give them the answers they need in a timely manner to help inform their diagnoses and treatment decisions.

National Direct Sales Force

Our direct sales force has been trained extensively in cancer genetic testing and consultative selling skills to service the needs of clients. Our sales team for the clinical cancer
testing services is organized into ten regions. Our Pharma Services segment has a dedicated team of business development specialists who are experienced in working with
pharma sponsors and helping them with the testing needs of their research and development projects as well as Phase 1-3 studies. These sales representatives utilize our custom
Customer Relationship Management System (“CRM”) to manage their territories, and we have integrated all of the important customer care functionality within our LIS into
the CRM so that our sales representatives can stay informed of emerging issues and opportunities within their regions. Our in-house customer care team is aligned with our field
sales team to serve the needs of our clients by utilizing the same LIS and CRM. Our field teams can see in real-time when a client calls the laboratory, the reason for the call, the
resolution, and if face-to-face interaction is needed for follow-up.

Seasonality

The majority of our clinical testing volume is dependent on patients being treated by hematology/oncology professionals and other healthcare providers. The volume of our
testing services generally declines modestly during the summer vacation season, year-end holiday periods and other major holidays, particularly when those holidays fall during
the middle of the week. In addition, the volume of our testing tends to decline due to extreme adverse weather conditions, such as excessively hot or cold spells, heavy snow,
hurricanes or tornados in certain regions, consequently reducing revenues and cash flows in any affected period. During the third quarter of 2017, Hurricane Harvey forced the
closure  of  our  Houston  laboratory  for  three  days  and  Hurricane  Irma  forced  the  closure  of  our  Fort  Myers  facility  for  five  days. Therefore,  comparison  of  the  results  of
successive periods may not accurately reflect trends for future periods.

In our Pharma Services business, we enter into both short term and long term contracts, ranging from one month to several years.  While the volume of this testing is not as
directly  affected  by  seasonality  as  described  above,  the  testing  volume  does  vary  based  on  the  terms  of  the  contract.    Many  of  our  long  term  contracts  contain  specific
performance  obligations  whereas  the  testing  is  performed  on  a  specific  schedule.    This  results  in  revenue  that  is  not  consistent  among  periods.    In  addition,  this  results  in
backlog that can be significant.  

Competition

For our Clinical Services segment, the genetic and molecular testing niche of the laboratory testing industry is highly competitive and, given the opportunities in this industry,
we expect it to become even more competitive. Competitive factors in genetic and molecular testing generally include the reputation of the laboratory, range of services offered,
pricing, convenience

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of sample collection and pick-up, quality of analysis and reporting, medical staff, timeliness of delivery of completed reports (i.e. turnaround times) and post-reporting follow-
up for clients.

Our competitors for our Clinical Services segment in the United States are numerous and include major national medical testing laboratories, hospital laboratories and in-house
physician  laboratories.    Some  of  our  competitors  have  greater  financial  resources  and  production  capabilities  than  us.  These  companies  may  succeed  in  developing  service
offerings  that  are  more  effective  than  any  that  we  have  or  may  develop,  and  may  also  prove  to  be  more  successful  than  we  are  in  marketing  such  services.  In  addition,
technological advances or different approaches developed by one or more of our competitors may render our service offerings obsolete, less effective or uneconomical.  

We  intend  to  continue  our  efforts  to  gain  market  share  by  offering  industry-leading  turnaround  times,  a  broad  service  menu,  high-quality  test  reports,  new  tests  including
proprietary ones, enhanced post-test consultation services, and the personal attention from our direct sales force. In addition, we believe our flexible reporting solutions, which
enable clients to report out customized results in a secure, real-time environment, will allow us to continue to gain market share.

Our Pharma Services business competes against many other clinical research organizations and central reference laboratories.  Many of these competitors are much larger and
have a greater international presence than we do.  Over the past few years, we have expanded our Pharma Services business into Europe and Asia at the request of our clients
and believe that our state of the art testing menu and our high level of service along with our international expansion will allow us to continue to gain market share in this
segment. The market for oncology clinical trials continues to grow and we expect to benefit from such overall market growth.

Our Pharma Services segment competitors are numerous Contract Resource Organizations or (“CRO”). These competitors are larger than NeoGenomics and have global
operations including operations in some areas where we do not yet have service capabilities.  These laboratories may be more effective than us in gaining business for global
clinical trials.  Many clinical reference laboratories have also entered the space in support of clinical trials and the related laboratory testing.  These reference laboratories can
often compete with lower pricing for smaller more limited studies.  We believe our service focus and our leading molecular and immunohistochemistry platforms, as well as our
exclusive MultiOmyxTM platform will continue to lead to rapid growth in this segment.

Suppliers

The Company orders its laboratory and research supplies from large national laboratory supply companies. We do not believe a short term disruption from any one of these
suppliers would have a material effect on our business.

Concentrations of Credit Risk

Concentrations  of  credit  risk  with  respect  to  revenue  and  accounts  receivable  are  primarily  limited  to  certain  clients  and  geographies  to  which  the  Company  provides  a
significant volume of its services, and to specific payers of our services such as Medicare and individual insurance companies.

Geographic Information

In 2017, we expanded internationally and have opened locations in Rolle, Switzerland and Singapore; revenues from non U.S. locations comprise an immaterial amount of total
revenue for 2017 and 2018.

Dependence on Major Clients

We  market  our  services  to  pathologists,  oncologists,  urologists,  other  clinicians,  hospitals,  pharmaceutical  companies,  academic  centers  and  other  clinical  laboratories
throughout the United States, Europe and Asia. The Company’s client base consists of a large number of geographically dispersed clients diversified across various customer
types. For the years ended December 31, 2018, 2017 and 2016, no single client accounted for more than 10% of revenue.  

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Payer Mix

The following table reflects our estimate of the breakdown of net clinical revenue by type of payer for the fiscal years ended December 31, 2018, 2017 and 2016:

Medicare and other government
Commercial insurance
Client direct billing

Total

2018

2017 
(as adjusted)

2016 
(as adjusted)

15 %
17 %
68 %

100 %

14  %
17  %
69  %

100  %

15  %
25  %
60  %

100  %

Our proportion of client direct billing has increased over the years shown above, as more payers, including Medicare, private commercial insurances and Medicare Advantage
plans, are practicing “consolidated payment” or “bundled payment” models where they pay the hospitals a lump sum, which is intended to include laboratory testing.  This
reflects an increase in the amount of risk sharing that CMS and other private payers are encouraging providers such as hospital systems to undertake.  We anticipate a gradual
increase in the percentage of client direct billing in the coming years. All of our Pharma Services revenue is billed directly to clients, or the pharmaceutical sponsor.

Trademarks

The “NeoGenomics”,“Genoptix” and “Clarient” names and logos have been trademarked with the United States Patent and Trademark Office. We have also trademarked or
have  applications  pending  for  the  brand  names  NeoFISH,  NeoFLOW,  NeoSITE,  NeoArray,  NeoTYPE,  NeoSCORE,  NeoLAB,  NeoLINK,  MultiOmyx,  CO MPASS,  and
CHART. We have also trademarked the marketing slogans, “When time matters and results count” and “Time matters, results count.”

Insurance

We maintain professional liability and numerous other insurance policies. We believe that our present insurance is sufficient to cover currently estimated exposures, but we
cannot  assure  that  we  will  not  incur  liabilities  in  excess  of  the  policy  coverage  limits.  In  addition,  although  we  believe  that  we  will  be  able  to  continue  to  obtain  adequate
insurance coverage, we cannot assure that we will be able to do so at acceptable cost.

Available Information

Our internet website address is www.neogenomics.com. Our Annual Report on Form 10-K, Quarterly Reports on Form 10-Q, Current Reports on Form 8-K and amendments to
those reports filed or furnished pursuant to section 13(a) or 15(d) of the Exchange Act are available free of charge through our website as soon as reasonably practicable after we
electronically  file  with  or  furnish  them  to  the  SEC,  and  are  available  in  print  to  any  stockholder  who  requests  a  copy.  Information  on  our  website  shall  not  be  deemed
incorporated into, or to be part of, this Annual Report on Form 10-K.

Additionally,  the  SEC  maintains  a  website  that  contains  reports,  proxy  statements,  information  statements  and  other  information  regarding  issuers,  including  us,  that  file
electronically with the SEC at www.sec.gov.

Employees

As of December 31, 2018, the Company had approximately 1,500 full-time equivalent employees and contracted pathologists. Our employees are not represented by any union
and we believe our employee relations are good.

Government Regulation

The laboratory business is subject to extensive governmental regulation at the federal, state and local levels. Our laboratories are required to be licensed by the states, certified
by  the  federal  government  to  participate  in  the  Medicare  and  Medicaid  programs,  and  are  subject  to  extensive  requirements  as  a  condition  of  participation  in  various
governmental health benefits programs. The failure to comply with any of the applicable federal and state laws, regulations, and reimbursement guidelines could have a material
adverse  effect  on  the  Company’s  business.  The  applicable  laws  and  regulations,  and  the  interpretations  of  them,  change  frequently  and  there  can  be  no  assurance  that  the
Company will not be subject to audit, inquiry, or investigation with respect to some aspect of its operations. Some of the federal and state laws and regulations are described
below  under  “Clinical  Laboratory  Operations,”  “Anti-Fraud  and  Abuse  Laws,”  “The  False  Claims  Act,”  “Confidentiality  of  Health  Information”  and  “Food  and  Drug
Administration”.

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Clinical Laboratory Operations

Licensure and Accreditation

The  Company  operates  clinical  laboratories  in  Florida,  Georgia,  Tennessee,  Texas  and  California.  The  laboratories  are  licensed  as  required  by  the  states  in  which  they  are
located. In addition, the laboratories in Fort Myers, Florida, Aliso Viejo and Carlsbad, California, and Nashville, Tennessee are licensed by the State of New York as they accept
clinical specimens obtained in New York.  All of our domestic laboratories are certified in accordance with the Clinical Laboratory Improvement Amendments, as amended
(“CLIA”). Under CLIA, the U.S. Department of Health and Human Services (“HHS”) establishes quality standards for each category of testing performed by the laboratory.
The categories of testing include waived, moderate complexity and high complexity. NeoGenomics’ laboratories are categorized as high complexity. Six of the ten site locations
for NeoGenomics’ laboratories are also accredited by the College of American Pathologists (“CAP”) and actively participate in CAP’s proficiency testing programs for all tests
offered by the Company. Our Tampa, Florida and Fresno, California facilities are read-only laboratories and, therefore, wouldn’t qualify for CAP accreditation.  Proficiency
testing  programs  require  the  participating  laboratories  to  test  specimens  that  they  receive  from  the  testing  entity  and  return  the  results.  The  testing  entity,  conducting  an
approved program, analyzes the results returned and provides to the Company a quality control report assessing the results. An important component of a quality assurance
program is to establish whether the laboratory’s test results are accurate and valid.

The federal and state certification and licensure programs establish standards for the operation of clinical laboratories, including, but not limited to, qualifications of personnel
and  quality  control.  Compliance  with  such  standards  is  verified  by  periodic  inspections  by  inspectors  employed  by  federal  and  state  regulatory  agencies  and  accrediting
organizations. The Company has a Quality Management System meeting applicable regulatory requirements and industry standards.

Quality of Care

Our mission is to improve patient care through quality cancer genetic diagnostic services. By delivering exceptional service and innovative solutions, we aspire to become the
world’s  leading  cancer  and  information  company.  The  quality  of  care  provided  to  clients  and  their  patients  is  of  paramount  importance  to  us.  We  maintain  quality  control
processes,  including  standard  operating  procedures,  controls,  performance  measurement  and  reporting  mechanisms.  Our  employees  are  committed  to  providing  accurate,
reliable and consistent services at all times. Any concerns regarding the quality of testing or services provided by the Company are immediately communicated to our Medical
Team, Company management and, if necessary, the Director for Quality Systems, the Compliance Department or Human Resources Department.  We also continually revise
and improve our tests and work with laboratory equipment vendors to ensure that our laboratory has the highest possible quality.

Compliance Program

The health care industry is highly regulated and scrutinized with respect to fraud, abusive billing practices and improper financial relationships between health care companies
and their referral sources. The Office of the Inspector General of HHS (the “OIG”) has published compliance guidance, including the Compliance Program Guidance for Clinical
Laboratories  in August  of  1998,  and  advisory  opinions.  The  Company  has  implemented  a  robust  Compliance  Program,  which  is  overseen  by  our  Board  of  Directors.  Its
objective  is  to  ensure  compliance  with  the  myriad  of  federal  and  state  laws,  regulations  and  governmental  guidance  applicable  to  our  business.  Our  program  consists  of
training/education  of  employees  and  monitoring  and  auditing  Company  practices.  The  Board  of  Directors  has  formed  a  Compliance  Committee  of  the  Board,  which  meets
regularly to discuss all compliance-related issues that may affect the Company. The Company reviews its policies and procedures as new regulations and interpretations come to
light to comply with applicable regulations. The Chief Compliance Officer reports directly to the Compliance Committee.

Hotline

As  part  of  its  Compliance  Program,  the  Company  provides  a  hotline  for  employees  who  wish  to  anonymously  or  confidentially  report  suspected  violations  of  our  codes  of
conduct, policies/procedures, or laws and regulations. Employees are strongly encouraged to report any suspected violation if they do not feel the problem can be appropriately
addressed through the normal chain of command. The hotline does not replace other resources available to our employees, including supervisors, managers and human resources
staff, but is an alternative channel available 24 hours a day, 365 days a year. The hotline forwards all reports to the Compliance Officer who is responsible for investigating,
reporting to the Compliance Committee, and documenting the disposition of each report. The hotline forwards any calls pertaining to the financial statements or financial issues
to the Chairman of the Audit Committee. The Company does not allow any retaliation against an employee who reports a compliance related issue in good faith.

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Laboratory Developed Tests (“LDTs”)

The FDA has regulatory responsibility over, among other areas, instruments, test kits, reagents and other medical devices used by clinical laboratories to perform diagnostic
testing. High complexity and CLIA-certified laboratories, such as ours, frequently develop internal testing procedures to provide diagnostic results to customers. These tests are
referred to as laboratory developed tests (“LDTs”). LDTs are subject to CMS oversight through its enforcement of CLIA. The FDA has also claimed regulatory authority over
all LDTs, but indicates that it has exercised enforcement discretion with regard to most LDTs offered by high complexity CLIA-certified laboratories, and has not subjected
these tests to FDA rules and regulations governing medical devices. However, the FDA has stated that it has been considering changes in the way it believes that laboratories
ought to be allowed to offer these LDTs, and since 2010 publicly announced that it would be exercising regulatory authority over LDTs, using a risk-based approach that will
direct more resources to tests with the highest risk of injury. On July 31, 2014 the FDA issued a notification to Congress of the “Anticipated Details of the Draft Guidance for
Industry, Food and Drug Administration Staff, and Clinical Laboratories: Framework for Regulatory Oversight of Laboratory Developed Tests,” or the Draft LDT Guidance.  As
described in this notification, the FDA planned to provide draft guidance to clinical laboratories that develop their own LDTs regarding how the FDA intends to regulate such
laboratories under the Federal Food, Drug, and Cosmetic Act. In October 2014, the FDA published Draft LDT Guidance setting forth its proposed framework and timetable for
regulating LDTs. The FDA received numerous comments both in support of and opposed to the draft guidance.  The FDA provided an opportunity for public comment through
February  2015  and  received  numerous  public  comments  in  response  to  the  Draft  LDT  Guidance.  The  FDA  then  announced  that  it  would  not  be  finalizing  the  draft
guidance.    On  January  13,  2017,  FDA  published  a  non-binding  Discussion  Paper  to  “advance  the  public  discussion  by  providing  a  possible  approach  to  spur  further
dialogue.”  The Discussion Paper sets forth a possible LDT regulatory approach where LDTs currently on the market would be exempt from FDA regulation except for adverse
event and malfunction reporting, and regulation of new and modified LDTs would be phased in over four years, based on risk. Recently, Congress has submitted a legislative
discussion draft, the Diagnostic Accuracy and Innovation Act (“DAIA”) to the FDA and requested technical assistance on the draft. FDA’s technical assistance consisted of
recommendations  for  significant  changes  to  the  bill. In  December  2018,  Congress  released  an  updated  bill,  the  Verifying  Accurate  Leading-edge  IVCT  Development
(“VALID”) Act that is largely consistent with FDA’s technical assistance on DAIA.  However, it remains unknown whether Congress will enact legislation regulating LDTs
and, if so, whether the legislation will be similar to the framework described in the Draft LDT Guidance, or in the VALID Act. It is possible that legislation and resulting FDA
regulation may result in increased regulatory burdens for us to register and continue to offer our tests or to develop and introduce new tests, or modify existing tests and may
increase our costs.  We cannot be certain as to which of our tests would require FDA review and approval, and if approval was to be required, that our tests could obtain FDA
approval.

The federal laws governing Medicare, Medicaid and other federal health benefits, as well as other state and federal laws, regulate certain aspects of the relationships between
health care providers, including clinical laboratories, and their referral sources, including physicians, hospitals, other laboratories and other entities. We are subject to the federal
Anti-Kickback Statute (“federal AKS”), as well as similar state statutes and regulations, which prohibit the offer, payment, solicitation or receipt of any form of remuneration in
return for referring, ordering, leasing, purchasing or arranging for or recommending the ordering, purchasing or leasing of items or services payable by Medicare, Medicaid or
any  other  federally  funded  healthcare  program.  The  federal AKS  defines  remuneration  to  include  anything  of  value,  in  cash  or  in  kind,  and  thus  can  implicate  financial
relationships including payments not commensurate with fair market value, such as in the form of space, equipment leases, professional or technical services or anything else of
value.

The federal AKS is an “intent-based” statute, meaning that a violation occurs when one or both parties intend the remuneration to be in exchange for or to induce referrals.
Violations of the federal AKS may result in substantial civil or criminal penalties, including criminal fines of up to $100,000, imprisonment of up to ten years, civil penalties
under  the  federal  CMP  Law  of  up  to  $100,000  for  each  violation,  plus  three  times  the  remuneration  involved,  civil  penalties  under  the  federal  False  Claims Act  of  up  to  a
minimum of $11,181 and a maximum of $22,363 for each claim submitted, plus three times the amounts paid for such claims and exclusion from participation in the Medicare
and Medicaid programs.

Because of the broad proscriptions of the federal AKS, there are both statutory exceptions and regulatory safe harbors promulgated by HHS (collectively, the “Safe Harbors”).
The Safe Harbors specify certain arrangements or activities that would not be considered prohibited remuneration in violation of the federal AKS. An arrangement or activity
that does not meet all of the criteria of an applicable Safe Harbor is not deemed to be illegal per se, rather it may be subject to additional scrutiny by government regulators. The
Company endeavors to comply with any applicable Safe Harbors, but there can be no assurance that the Company would not be subject to investigation and, if investigated, that
relationships could be found not to comply with such Safe Harbors.

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Further,  most  states  have  adopted  similar  anti-kickback  laws  prohibiting  the  offer,  payment,  solicitation  or  receipt  of  remuneration  in  exchange  for  referrals,  and  typically
impose criminal and civil penalties as well as loss of licenses. Some of these state laws apply to items and services paid for by private payers as well as to government payers. In
addition, many states have adopted laws prohibiting the splitting or sharing of fees between physicians and non-physicians, as well as between treating physicians and referral
sources. We believe our arrangements with physicians comply with the federal AKS, and state anti-kickback and fee splitting laws of the states in which we operate, however, if
government regulatory authorities were to disagree, we could be subject to civil and criminal penalties, and be required to restructure or terminate our contractual and other
arrangements with physicians. This could result in a loss of revenue and have a material adverse effect on our business.

Medicare Payment Guidelines

We have various billing arrangements with our clients and with third party payers, including the Medicare program. When the Company bills the client for all, or a portion of, a
laboratory test performed, these client billing arrangements are priced competitively at fair market value. These client billing arrangements may implicate the prohibition of the
Medicare program against charging the Medicare or Medicaid programs fees substantially in excess of the Company’s usual and customary charges.  Given our participation in
Medicare and Medicaid, we are subject to the federal Stark Law and the federal and state anti-kickback statutes.

Federal law authorizes the Secretary of HHS to suspend or exclude providers from participation in the Medicare and Medicaid programs if providers charge Medicare or state
Medicaid programs fees “substantially in excess” of their “usual charges.” In commentary the OIG has noted that “ancillary services, such as laboratory tests and drugs, would
remain subject to these regulations, even when furnished by physicians.” 68 Fed. Reg. 53,939, 53,940 (Sept. 15, 2003). As such, the government could scrutinize the Company’s
pricing and billing practices.

The  Centers  for  Medicare  and  Medicaid  Services  promulgated,  in  2009,  a  revision  to  the  regulation  that  prohibits  the  mark  up  of  purchased  diagnostic  services  42  C.F.R.
§414.50 (the “Anti-Markup Rule”). The Anti-Markup Rule prohibits a physician or other supplier from marking up the price paid for the technical or professional component of
a  diagnostic  test  that  was  ordered  by  the  billing  physician  or  supplier  and  which  was  performed  by  a  physician  who  does  not  share  a  practice  with  the  billing  physician  or
supplier.  The  billing  physician  is  prohibited  from  billing  the  Medicare  program  an  amount  greater  than  the  lesser  of:  (i)  the  performing  supplier’s  net  charge  to  the  billing
physician; (ii) the billing physician’s actual charge; or (iii) the fee schedule amount for the test that would be allowed if the performing supplier billed directly.

In light of the various federal regulations and guidance from the OIG, the Company seeks to price its products competitively while endeavoring to meet applicable statutes and
regulations.

Physician Self-Referral Laws

The  federal  law  referred  to  as  the  “Stark  Law”,  named  after  U.S.  Representative  Fortney  “Pete”  Stark,  prohibits payments  for  certain  health  care  services,  referred  to  as
designated health services or “DHS,” which were rendered as a result of referrals by physicians to DHS entities with which the physicians (or their immediate family members)
have a financial relationship. A “financial relationship” includes both an ownership interest and/or a compensation arrangement with a physician, both direct and indirect, and
DHS includes, but is not limited to, laboratory services.

The Stark Law prohibits an entity that receives a prohibited DHS referral from seeking payment from Medicare and Medicaid for any DHS services performed as a result of
such  a  referral,  unless  an  arrangement  is  carefully  structured  to  satisfy  every  requirement  of  a  regulatory  exception.  The  Stark  Law  is  a  strict  liability  statute,  and  thus  any
technical violation requires repayment of all “tainted” referrals, regardless of the intent, unless an exception applies. Penalties for violating the Stark Law may include the denial
of payment to an entity for the impermissible provision of DHS, the requirement to refund any amounts collected in violation of the Stark Law, and civil monetary penalties of
up  to  $24,748  for  each  violation  and  $164,992  for  each  circumvention  arrangement  or  scheme. The  amounts  may  be  further  increased  by  civil  monetary  penalty  increases
imposed by the Bipartisan Budget Act of 2018.  Other implications of a Stark Law violation may include criminal penalties, exclusion from Medicare and Medicaid programs,
and potential False Claims Act liability, including via “qui tam” action. The Company endeavors to structure its financial relationships in compliance with the Stark Law and
with similar state physician self-referral laws.

Further, many states have promulgated self-referral laws and regulations similar to the federal Stark Law, but these vary significantly based on the state. In addition to services
reimbursed by Medicaid or government payers, often these state laws and regulations can encompass services reimbursed by private payers as well. Penalties for violating state
self-referral laws and regulations vary based on the state, but often include civil and criminal penalties, exclusion from Medicaid, and loss of licenses.

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Our financial arrangements with physicians are governed by the federal Stark Law and similar state self-referral laws, and we rely on certain exceptions to the Stark Law with
respect to such relationships. While we believe that our financial relationships with physicians and referral practices are in compliance with applicable laws and regulations, we
cannot guarantee that government authorities would agree. If we are found by the government to be in violation of the Stark Law or a similar state self-referral law, we could be
subject to significant penalties, including fines as specified above, exclusion from participation in government and private payer programs and requirements to refund amounts
previously received from government.

The False Claims Act

The  federal  False  Claims Act  prohibits  any  person  or  entity  from  knowingly  presenting,  or  causing  to  be  presented,  to  the  U.S.  government,  or  to  a  Medicare  program
contractor, a false or fraudulent claim for payment, or knowingly making or using a false record or statement to have a false claim paid by the government, or conspiring to
defraud the U.S. government, or knowingly making or using a false statement to conceal an obligation to pay the government, or improperly retaining overpayments from, the
government. Following enactment of the ACA, knowing retention of overpayments is also considered a false claim and could lead to liability under the False Claims Act. A
violation of the federal False Claims Act is punishable by a civil penalty of a minimum of $11,181 and a maximum of 22,363 for each separate false claim plus three times the
amount  of  damages  sustained  by  the  government.  Further,  False  Claims  Act  liability  may  lead  to  exclusion  from  participation  in  Medicare,  Medicaid  and  other  federal
healthcare programs. The False Claims Act’s “whistleblower” or “qui tam” provisions are being used with more frequency to challenge the reimbursement practices of providers
and suppliers. Those provisions allow a private individual to bring an action on behalf of the government alleging that the defendant has submitted false claims for payment to
the federal government. The government must decide whether to intervene in the lawsuit and whether to prosecute the case. If it declines to do so, the individual may pursue the
case  alone,  although  the  government  must  be  kept  apprised  of  the  progress  of  the  lawsuit.  Whether  or  not  the  federal  government  intervenes  in  the  case,  it  will  receive  the
majority of any recovery. The successful qui tam relator who brought the case is entitled to a portion of the proceeds and its attorneys’ fees and costs. As most qui tam cases are
filed by current or former employees, an effective compliance program plays a crucial role in reducing the Company’s exposure to liability. It is also a criminal offense, under
Title  18  U.S.  Code,  Section  287,  for  a  person  or  entity  to  make  a  claim  against  the  United  States  or  any  department  or  agency,  knowing  the  claim  to  be  false,  fictitious  or
fraudulent. The penalty is a fine, and imprisonment of up to five years. The federal False Claims Act has been an effective enforcement tool for the federal government. Many
states have enacted similar false claims acts as well.

The Company seeks to structure its arrangements with physicians and other clients to be in compliance with the Anti-Kickback Statute, Stark Law, state laws, and the federal
False  Claims Act  and  to  stay  abreast  of  current  developments  and  changes  in  the  law  and  regulations.  However,  these  laws  and  regulations  are  complex  and  subject  to
interpretation. Consequently, we are unable to ascertain with certainty that any of our transactions will not be subject to scrutiny and, if scrutinized, will not result in sanctions or
penalties. The Company has taken, and will continue to take, actions to endeavor to ensure compliance with the myriad federal and state laws that govern our business.

Confidentiality and Security of Personal Health Information

The Health Insurance Portability and Accountability Act of 1996, as amended (“HIPAA”), contains provisions that protect individually identifiable health information from
unauthorized use or disclosure by covered entities and their business associates. The Office for Civil Rights of HHS, the agency responsible for enforcing HIPAA, has published
regulations  to  address  the  privacy  (the  “Privacy  Rule”)  and  security  (the  “Security  Rule”)  of  protected  health  information  (“PHI”).  The  Company  is  a  covered  entity  under
HIPAA  and  has  adopted  policies  and  procedures  to  comply  with  the  Privacy  Rule  and  the  Security  Rule  and  HIPAA.  The  health  care  facilities  and  providers  that  refer
specimens  to  the  Company  are  also  bound  by  HIPAA.    HIPAA  also  requires  that  all  providers  who  transmit  claims  for  health  care  goods  or  services  electronically  utilize
standard  transaction  and  data  sets  and  use  standardized  national  provider  identification  codes.  The  Company  has  taken  necessary  steps  to  comply  with  HIPAA  regulations,
utilizes standard transaction data sets, and has obtained and implemented national provider identifiers, or NPIs, as the standard unique health identifier in filing and processing
health care claims and other transactions.

The American Recovery and Reinvestment Act (“ARRA”) enacted the HITECH Act which extends the scope of HIPAA to permit enforcement against business associates for a
violation,  establishes  new  requirements  to  notify  the  Office  for  Civil  Rights  of  a  breach  of  PHI,  and  allows  the Attorneys  General  of  the  states  to  bring  actions  to  enforce
violations of HIPAA. Rules implementing various aspects of HIPAA are continuing to be promulgated. With respect to these rules, commencing July 1, 2012, CMS required all
HIPAA-covered  entities  such  as  the  Company  to  conduct  electronic  claim  submissions  and  related  electronic  transactions  under  a  new  HIPAA  transaction  standard  called
Version 5010.

In addition to the HIPAA Privacy Rule and Security Rule described above, the Company is subject to state laws regarding the handling and disclosure of patient records and
patient health information. The HIPAA Privacy Rule and Security Rule

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regulations do not supersede state laws that may be more stringent; therefore, we are required to comply with both federal privacy and security regulations and varying state
privacy and security laws and regulations. These laws vary widely. Penalties for violation include sanctions against a laboratory’s licensure as well as civil or criminal penalties.
Additionally, private individuals may have a right of action against the Company for a violation of a state’s privacy laws. We believe we are in material compliance with current
state laws regarding the confidentiality of health information and will continue to monitor and comply with new or changing state laws.

The Fair and Accurate Credit Transactions Act of 2003, enacted on Dec. 4, 2003, directed the Federal Trade Commission to implement regulations to protect consumers against
identity theft. The Federal Trade Commission issued what are referred to as the “Red Flag Rules”, but the effective date for enforcement was delayed several times. The Red
Flag  Rules  were  subject  to  enforcement  as  of  January  1,  2012.  The  Red  Flag  Program  Clarification Act  of  2010  (“RFPCA”)  gave  some  relief  to  health  care  providers  by
changing the definition of “creditor”, thereby narrowing the application to health care providers who do not otherwise obtain or use consumer reports or furnish information to
consumer reporting agencies in connection with a credit transaction. Health care providers who act as a “creditor” to any of its patients with respect to a “covered account” are
required to implement an identity theft protection program to safeguard patient information. A creditor includes any entity that regularly in the course of business obtains or
uses consumer reports in connection with credit transactions, furnishes information to a consumer reporting agency in connection with a credit transaction, or advances funds to
or on behalf of a person based on the person’s obligation to repay the funds or repayable from specific property pledged by or on behalf of the person. But, a creditor, as defined
in the RFPCA, that advances funds on behalf of a person for expenses incidental to a services provided by the creditor to that person is not subject to the Red Flag Rules. The
Company has developed a written program designed to identify and detect the relevant warning signs – or “red flags” – of identity theft and establish appropriate responses to
prevent and mitigate identity theft in order to comply with the Red Flag Rules. We are also developing a plan to update the program, and the program will be managed by senior
management staff under the policy direction of our Board of Directors. The Company intends to take such steps as necessary to determine the extent to which the Red Flag
Rules apply to it and to take such steps as necessary to comply.

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ITEM 1A. RISK FACTORS

We are subject to various risks that may materially harm our business, financial condition and results of operations. They are not, however, the only risks we face. Additional
risks  and  uncertainties  not  presently  known  to  us  or  that  we  currently  believe  not  to  be  material  may  also  adversely  affect  our  business,  financial  condition  or  results  of
operations. An investor should carefully consider the risks and uncertainties described below and the other information in this filing before deciding to purchase our common
stock. If any of these risks or uncertainties actually occurs, our business, financial condition or operating results could be materially harmed. In that case, the trading price of our
common stock could decline or we may be forced to cease operations.

Risks Relating to Our Business

Our business is subject to rapid scientific change, which could have a material adverse effect on our business, results of operations and financial condition.

The market for genetic and molecular testing services is characterized by rapid scientific developments, evolving industry standards and customer demands, and frequent new
product  introductions  and  enhancements.  For  example,  new  tests  developed  by  our  competitors  may  prove  superior  and  replace  our  existing  tests.  Additionally,  certain
technological changes such as advances in point-of-care testing, could reduce the need for the laboratory tests we provide. Our future success will depend in significant part on
our ability to continually improve our offerings in response to both evolving demands of the marketplace and competitive service offerings, and we may be unsuccessful in
doing so, which could have a material adverse effect on our business, results of operations and financial condition.  

Increased competition, including price competition, could have a material adverse impact on our net revenues and profitability.

The  market  for  genetic  and  molecular  testing  services  is  highly  competitive  and  we  expect  competition  to  continue  to  increase.  Our  major  competitors  including  Quest
Diagnostics  and  Laboratory  Corporation  of America,  are  large  national  laboratories  that  possess  greater  name  recognition,  larger  customer  bases,  and  significantly  greater
financial resources and employ substantially more personnel than we do. Our competitors may develop products and services that are superior to ours or that achieve greater
market acceptance than our offerings. Many of our competitors have long established relationships with their customers and third-party payers. We cannot assure you that we
will be able to compete successfully with such entities in the future.

The laboratory business is intensely competitive both in terms of price and service. Pricing of laboratory testing services is often one of the most significant factors used by
health care providers and third-party payers in selecting a laboratory. As a result of the laboratory industry undergoing consolidation, larger laboratory providers are able to
increase  cost  efficiencies  afforded  by  large-scale  automated  testing.  This  consolidation  results  in  greater  price  competition.  We  may  be  unable  to  increase  cost  efficiencies
sufficiently, if at all, and as a result, our net earnings and cash flows could be negatively impacted by such price competition. Additionally, we may also face changes in fee
schedules, competitive bidding for laboratory services or other actions or pressures reducing payment schedules as a result of increased or additional competition.

Additional competition, including price competition, could have a material adverse impact on our net revenues and profitability.

We face the risk of capacity constraints, which could have a material adverse effect on our business, results of operations and financial condition.

We compete in the market place primarily on three factors: i) the quality and accuracy of our test results; ii) the speed or turn-around times of our testing services; and iii) our
ability to provide after-test support to those physicians requesting consultation. Any unforeseen increase in the volume of clients could strain the capacity of our personnel and
systems, leading to unacceptable turn-around times, or customer service failures. In addition, as the number of our clients and specimens increases, our products, services, and
infrastructure may not be able to scale accordingly. We may also not be able to hire additional licensed medical technologists that we need to handle increased volumes. Any
failure to handle higher volume of requests for our products and services could lead to the loss of established clients and have a material adverse effect on our business, results
of operations and financial condition. If we produce inaccurate test results, our clients may choose not to use us in the future. This could severely harm our business, results of
operations and financial condition. In addition, based on the importance of the subject matter of our tests, inaccurate results could result in improper treatment of patients, and
potential liability for us.

Failure to develop, or acquire licenses for, new or improved testing technologies could materially and adversely affect our revenues.

Our industry is subject to rapidly changing technology and new product introductions. Other companies or individuals, including our competitors, may obtain patents or other
property rights that would prevent, limit or interfere with our ability to develop, perform or sell our solutions or operate our business or increase our costs. In addition, they
could introduce new tests, technologies or services that may result in a decrease in the demand for our services or cause us to reduce the prices of our

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services. Our success will depend, in part, on our ability to develop, acquire or license new and improved technologies on favorable terms and to obtain appropriate coverage and
reimbursement  for  these  technologies.  We  may  not  be  able  to  negotiate  acceptable  licensing  arrangements  and  we  cannot  be  certain  that  such  arrangements  will  yield
commercially successful diagnostic tests. If we are unable to license these testing methods at competitive rates, our research and development costs may increase as a result. In
addition,  if  we  are  unable  to  license  new  or  improved  technologies  to  expand  our  testing  operations,  our  testing  methods  may  become  outdated  when  compared  with  our
competition and testing volume and revenue may be materially and adversely affected.

Clinical trials and research services create a risk of liability.

We conduct clinical trials, which ordinarily involve testing an investigational drug on a limited number of individuals to evaluate a product’s safety, determine a safe dosage
range  and  identify  side  effects.  Errors  or  omissions  could  occur  during  a  clinical  trial  that  may  result  in  harm  to  study  volunteers,  or  if  unnoticed  and  regulatory  approval
received, to consumers of the drug, or that undermine the usefulness of the clinical trial or data from the clinical trial and may delay the entry of a drug to the market.

Our contracts with the pharmaceutical firms include provisions entitling us to be indemnified or entitling us to a limitation of liability. These provisions do not uniformly protect
us against liability arising from certain of our own actions, such as gross negligence or misconduct. We could be materially and adversely affected if we were required to pay
damages or bear the costs of defending any claim which is not covered by or exceeds a contractual indemnification provision or in the event that a party who must indemnify us
does not fulfill its indemnification obligations or which is beyond the level of our insurance coverage.

Clinicians or patients using our services may sue us, and our insurance may not sufficiently cover all claims brought against us, which will increase our expenses.

The development, marketing, sale and performance of healthcare services expose us to the risk of litigation, including professional negligence or product liability claims were
someone to allege that our tests failed to perform as designed. We may also be subject to liability for errors in the test results we provide to pathologists and oncologists or for a
misunderstanding of, or inappropriate reliance upon, the information we provide. Damages assessed in connection with, and the costs of defending, any legal action could be
substantial. We may be faced with litigation claims that exceed our insurance coverage or are not covered under any of our insurance policies. In addition, litigation could have
a material adverse effect on our business if it impacts our existing and potential customer relationships, creates adverse public relations, diverts management resources from the
operation of the business, or hampers our ability to otherwise conduct our business.

We may not be able to implement our business strategy, which could impair our ability to continue operations.

Implementation of our business strategies will depend in large part on our ability to (i) attract and maintain a significant number of clients; (ii) effectively provide acceptable
products and services to our clients; (iii) develop and license new products and technologies; (iv) obtain adequate financing on favorable terms to fund our business strategies;
(v) maintain appropriate internal procedures, policies, and systems; (vi) hire, train, and retain skilled employees and management; (vii) continue to operate despite competition
in the medical laboratory industry; (viii) be paid reasonable fees by government payer’s that will adequately cover our costs; (ix) establish, develop and maintain our name
recognition; and (x) establish and maintain beneficial relationships with third-party insurance providers and other third-party payers. Our inability to obtain or maintain any or
all these factors could impair our ability to implement our business strategies successfully, which could have material adverse effects on our results of operations and financial
condition.

We may be unsuccessful in managing our growth which could prevent us from operating profitably.

Our  growth,  including  through  our  acquisition  of  the  Genoptix  business  in  December  2018,  has  placed,  and  is  expected  to  continue  to  place,  a  significant  strain  on  our
managerial, operational and financial resources. For example, the acquisition of Genoptix is expected to result in a combined company with annual revenues in excess of $379.0
million as compared to our annual revenues of $276.7 million for the year ended December 31, 2018.  To manage our expanded business and our potential growth, we must
continue  to  implement  and  improve  our  operational,  financial  and  billing  systems  and  to  expand,  train  and  manage  our  employee  base.  We  may  not  be  able  to  effectively
manage the expansion of our operations and our systems and our procedures or controls may not be adequate to support our operations. Our management may not be able to
achieve the rapid execution necessary to fully exploit the market opportunity for our products and services. Any inability to manage growth could have a material adverse effect
on our business, results of operations, potential profitability and financial condition.

We have a substantial amount of indebtedness.  This level of indebtedness could adversely affect our flexibility in operating our business and our ability to react to
changes in the economy or our industry.

On June 25, 2018, we entered into a second amendment to our senior secured revolving credit facility, which now provides for a $105.0 million senior secured term loan facility
and  a $75.0 million  revolving  credit  facility. At December 31, 2018,  we  had $96.7 million  and  $5.0  million  of  indebtedness  outstanding  under  the  senior  secured  term  loan
facility and revolving credit

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facility, respectively. We had $60.9 million of available borrowing capacity under the revolving credit facility.  The revolving credit facility allows for additional borrowings as
long as the debt to Adjusted EBITDA ratio remains below  4.0:1.0 for the quarter ending March 31, 2019 and 3.75:1.0 for the quarters ending June 30, 2019 and September 30,
2019,  and  as  specified  in  the  respective  agreements  for  future  quarters. Our  substantial  indebtedness  could  have  significant  consequences  for  our  business  and  financial
condition. For example:

• We  could  be  required  to  dedicate  a  greater  percentage  of  our  cash  flows  to  payments  on  our  debt,  thereby  reducing  the  availability  of  cash  flow  to  fund  capital
expenditures, pursue other acquisitions or investments in new technologies, make stock repurchases and fund other general corporate purposes. If we fail to meet our
payment obligations or otherwise fail to comply with the covenants in our debt, including failure as a result of events beyond our control, it could result in an event of
default on our debt. Upon an event of default, the lenders of that debt could elect to cause all amounts outstanding with respect to that debt to become immediately due
and payable and we would be unable to access our revolving credit facility. Our debt imposes operating and financial covenants and restrictions on us, and compliance
with such covenants and restrictions may adversely affect our ability to adequately finance our operations or capital needs, pursue attractive business opportunities that
may arise, redeem or repurchase capital stock, pay dividends, sell assets, and make capital expenditures.

• We  may  experience  increased  vulnerability  to  general  adverse  economic  conditions,  including  increases  in  interest  rates  for  those  borrowings  that  bear  interest  at

variable rates or if such indebtedness is refinanced at a time when interest are higher.

• We may experience limited flexibility in planning for, or reacting to, changes in or challenges relating to our businesses and industry, creating competitive disadvantages

compared to other competitors with lower debt levels and borrowing costs.

We  cannot  assure  you  that  cash  flows,  combined  with  additional  borrowings  under  the  revolving  credit  facility  or  any  future  credit  facility,  will  be  available  in  an  amount
sufficient to enable us to repay our indebtedness, or to fund other liquidity needs.

In addition, we may incur substantial additional indebtedness in the future, which could cause the related risks to intensify. We may need to refinance all or a portion of our
indebtedness on or before their respective maturities. We cannot assure you that we will be able to refinance any of our indebtedness on commercially reasonable terms or at all.
If we are unable to refinance our debt, we may default under the terms of our indebtedness, which could lead to an acceleration of the debt. We do not expect that we could
repay all of our outstanding indebtedness if the repayment of such indebtedness was accelerated.

The failure to obtain necessary additional capital to finance growth and capital requirements, could adversely affect our business, financial condition and results of
operations.

We may seek to exploit business opportunities that require more capital than we have currently available. We may not be able to raise such capital on favorable terms or at all,
and may be restricted in amount and type of such capital by the agreements governing our existing indebtedness. If we are unable to obtain such additional capital, we may be
required to reduce the scope of our anticipated expansion, which could adversely affect our business, financial condition and results of operations.

As of December 31, 2018, we had cash and cash equivalents of approximately $9.8 million  and  approximately $60.9 million in available borrowing capacity under our senior
secured  revolving  credit  facility. We may still need additional capital to fully implement our business, operating and development plans. Should the financing we require to
sustain  our  working  capital  needs  be  unavailable  or  prohibitively  expensive  when  we  require  it,  there  could  be  a  material  adverse  effect  on  our  long-term  business,  rate  of
growth, operating results, financial condition and prospects.

Changes in the use of LIBOR could adversely affect our business.

Financial regulators are working to transition away from the London Interbank Offered Rate (“LIBOR”) as a reference rate for financial contracts by the end of 2021 and to
develop benchmarks to replace LIBOR. Borrowings under our Term Loan Facility and our Revolving Credit Facility, which mature in December 2021, are derived from the
LIBOR  reference  rate.  The  interest  rate  swap  agreements  we  enter  into  to  reduce  our  exposure  to  interest  rate  fluctuations  on  our  credit  facilities  are  based  on  the  LIBOR
reference rate. Our credit agreement includes general provisions governing the use of an alternate rate of interest to the LIBOR-based rate based upon the rates used by the
Federal Reserve Bank or by Regions Bank, the administrative agent under our credit agreement. At this time, the impact on the Company's borrowing costs, if any, under an
alternative reference rate scenario is uncertain.

If we are unable to successfully integrate the Genoptix business, or any future business we may acquire, with our legacy business, the anticipated benefits of such
transaction may not be realized.

Acquisitions, including the acquisition of Genoptix, involve the combination of two companies that formerly operated as independent companies. Acquisitions require us to
devote  significant  management  attention  and  resources  to  integrating  the  acquired  company’s  business  practices  and  operations  with  our  own.  Potential  difficulties  we  may
encounter as part of the

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integration process, all of which could materially and adversely affect our business, financial condition, results of operations, and cash flows, include the following:

•

•

•

•

•

•

•

•

•

•

the  potential  inability  to  successfully  combine  the  acquired  company’s  business  with  our  legacy  business  in  a  manner  that  permits  us  to  achieve  the  cost  synergies
expected to be achieved when expected, or at all, and other benefits anticipated to result from such transaction;

challenges optimizing the customer information and technology of the two companies, including the goal of consolidating to one laboratory information system and one
billing system;

challenges effectuating any diversification strategy, including challenges achieving revenue growth from sales of each company’s products and services to the customers
of the other company;

difficulties offering products and services across our expanded portfolio;

the need to revisit assumptions about reserves, revenues, capital expenditures, and operating costs, including expected synergies;

challenges faced by a potential diversion of the attention of our management as a result of the integration, which in turn could adversely affect our ability to maintain
relationships with customers, employees and other constituencies or our ability to achieve the anticipated benefits of such transaction;

the potential loss of key employees, customers, managed care contracts or strategic partners, or the ability to attract or retain key management and other key personnel,
which could have an adverse effect on our ability to integrate and operate the acquired business;

complexities associated with managing the combined businesses, including difficulty addressing possible differences in corporate cultures and management philosophies
and the challenge of integrating complex systems, technology, networks and other assets of each of the companies in a seamless manner that minimizes any adverse
impact on customers, suppliers, employees and other constituencies;

costs and challenges related to the integration of the acquired company’s internal controls over financial reporting with ours; and

potential unknown liabilities and unforeseen increased expenses.

We cannot be assured that all of the goals and anticipated benefits of an acquisition, including the acquisition of Genoptix, will be achievable, particularly as the achievement of
the benefits are in many important respects subject to factors that we do not control. These factors would include such things as the reactions of third parties with whom we
enter into contracts and to business and the reactions of investors and analysts.

If we cannot integrate our legacy business and the Genoptix business, or any future business we may acquire, successfully, we may fail to realize the expected benefits of such
transaction, including the anticipated cost synergies. We could also encounter additional transaction and integration costs or be subject to other factors that affect preliminary
estimates.

We may be unable to make, on a timely basis, necessary changes to our internal control structure resulting from the acquisition of Genoptix.

Genoptix is now included in our reporting under the Securities Exchange Act of 1934. Under the Sarbanes-Oxley Act of 2002, we must maintain effective disclosure controls
and procedures and internal control over financial reporting. We are in the process of migrating Genoptix operations to our system of internal controls. Therefore, we may face
difficulties  or  experience  delays  in  developing  changes  or  potentially  necessary  improvements  to  Genoptix  internal  controls  and  accounting  systems  in  order  to  ensure
compliance with the requirements of the Sarbanes-Oxley Act. We may need to commit substantial resources, including substantial time from existing accounting personnel and
from  external  consultants,  to  implement  additional  procedures  and  improved  controls.  This  in  turn  could  have  an  adverse  effect  on  our  business,  results  of  operations,  or
financial condition, harm our reputation, or otherwise cause a decline in investor confidence and our stock price.

Genoptix may have liabilities that are not known, probable or estimable at this time.

Genoptix is now a wholly owned subsidiary of ours and there could be unasserted claims or assessments that we failed or were unable to discover or identify in the course of
performing due diligence investigations of Genoptix. In addition, there may be liabilities that are neither probable nor estimable at this time which may become probable and
estimable in the future. We may learn additional information about Genoptix that adversely affects us, such as unknown, unasserted or contingent liabilities and issues relating
to  compliance  with  applicable  laws,  including  federal  healthcare  laws.  For  example,  Genoptix  from  time  to  time  receives  payments  from  the  U.S.  government.  If  the  U.S.
government were to assert that Genoptix was not entitled to receive such payments in the amount provided, or at all, in light of applicable billing guidance, the government
could impose fines and penalties, in addition to recovery of the overpayments, under federal healthcare laws. Any of the foregoing, individually or in

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the aggregate, if not covered by the indemnification obligations of the Genoptix sellers or our representation and warranty insurance, could have a material adverse effect on our
business.

We may incur greater costs than anticipated, which could result in sustained losses.

We  use  reasonable  efforts  to  assess  and  predict  the  expenses  necessary  to  pursue  our  business  strategies.  However,  implementing  our  business  strategies  may  require  more
employees, capital equipment, supplies or other expenditure items than management has predicted, particularly as we continue to assess any further needs resulting from the
integration of Genoptix. Similarly, the cost of compensating additional management, employees and consultants or other operating costs may be more than we estimate, which
could result in ongoing and sustained losses.

Other manufacturers may discontinue or recall testing products used in our business.

We rely heavily on reagents, test kits and instruments manufactured by third parties in our testing services. From time to time, manufacturers discontinue or recall the reagents,
test kits or instruments used by us to perform laboratory testing. Such discontinuations or recalls could adversely affect our costs, testing volume, costs and revenues.

We may face fluctuations in our results of operations and we are subject to seasonality in our business which could negatively affect our business operations.

Management expects that our results of operations may fluctuate significantly in the future as a result of a variety of factors, including, but not limited to: (i) the continued rate
of growth, usage and acceptance of our products and services; (ii) demand for our products and services; (iii) the introduction and acceptance of new or enhanced products or
services by us or by competitors; (iv) our ability to anticipate and effectively adapt to developing markets and to rapidly changing technologies; (v) our ability to attract, retain
and  motivate  qualified  personnel;  (vi)  the  initiation,  renewal  or  expiration  of  significant  contracts  with  any  major  clients;  (vii)  pricing  changes  by  us,  our  suppliers  or  our
competitors; (viii) seasonality; and (ix) general economic conditions and other factors. Accordingly, future sales and operating results are difficult to forecast. Our expenses are
based in part on our expectations as to future revenues and to a significant extent are relatively fixed, at least in the short-term. We may not be able to adjust spending in a timely
manner  to  compensate  for  any  unexpected  revenue  shortfall. Accordingly,  any  significant  shortfall  in  relation  to  our  expectations  would  likely  have  an  immediate  adverse
impact  on  our  business,  results  of  operations  and  financial  condition.  In  addition,  we  may  determine  from  time  to  time  to  make  certain  pricing  or  marketing  decisions  or
acquisitions  that  could  have  a  short-term  material  adverse  effect  on  our  business,  results  of  operations  and  financial  condition  and  may  not  result  in  the  long-term  benefits
intended.  Furthermore,  in  Florida,  historically  our  largest  referral  market  for  laboratory  testing  services,  a  meaningful  percentage  of  the  population,  returns  to  homes  in  the
Northern United States to avoid the hot summer months. This combined with the usual summer vacation schedules of our clients usually results in seasonality in our business.
Because of all of the foregoing factors, our operating results in future periods could be less than the expectations of investors.

We depend substantially upon third parties for payment of services, which could have a material adverse effect on our cash flows and results of operations.

Our  business  consists  of  clinical  laboratories  that  provide  medical  testing  services  for  doctors,  hospitals,  and  other  laboratories  on  patient  specimens  that  are  sent  to  our
laboratory. In the case of some specimen referrals that are received for patients that are not in-patients or out-patients at a hospital or institution or otherwise sent by another
reference laboratory, we typically bill the patient’s insurance company or a government program for our services. As such, we rely on the cooperation of numerous third-party
payers, including but not limited to Medicare, Medicaid, and various insurance companies, to get paid for performing services on behalf of our clients and their patients. The
amount of such third-party payments is governed by contractual relationships in cases where we are a participating provider for a specified insurance company or by established
government reimbursement rates in cases where we are an approved provider for a government program such as Medicare or Medicaid. However, we do not have contractual
relationships with some of the insurance companies with whom we deal, nor are we necessarily able to become an approved provider for all government programs. In such
cases, we are deemed to be a non-participating provider and there is no contractual assurance that we will be able to collect the amounts billed to such insurance companies or
government programs. Currently, we are not a participating provider with some of the insurance companies we bill for our services. Until such time we become a participating
provider with such insurance companies, there can be no contractual assurance that we will be paid for the services we bill to such insurance companies or patients, and such
third-parties  may  change  their  reimbursement  policies  for  non-participating  providers  in  a  manner  that  may  have  a  material  adverse  effect  on  our  cash  flow  or  results  of
operations.  When  new  Current  Procedural  Terminology  (“CPT”)  codes  are  introduced  by  the American  Medical Association  it  often  takes  time  for  commercial  insurance
providers to recognize the new codes, which can significantly impact the timing of payments, if any, and can increase our days-sales-outstanding. Medicare has also, at times,
issued codes or coding guidance that conflicts with the AMA CPT coding, which can cause confusion when secondary insurance is involved.  Insurance companies may also try
to steer business away from us towards in-network providers by sending letters to physicians and even imposing financial penalties if they continue to send us business.

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We may fail to protect our facilities, which could have a material adverse effect on our business, results of operations and financial condition.

Our operations are dependent in part upon our ability to protect our laboratory operations against physical damage from explosions, fire, floods, hurricanes, earthquakes, power
loss, telecommunications failures, break-ins and similar events. We do not presently have an emergency back-up generator in place at our Tampa, Florida, Nashville, Tennessee,
Atlanta, Georgia, Rolle, Switzerland or Fresno, California laboratories locations which would otherwise mitigate to some extent the effects of a prolonged power outage. The
occurrence of any of these events could result in interruptions, delays or cessations in service to clients, which could have a material adverse effect on our business, results of
operations and financial condition.

The steps we have taken to protect our proprietary rights may not be adequate, which could result in infringement or misappropriation by third-parties.

We  regard  our  copyrights,  trademarks,  trade  secrets  and  similar  intellectual  property  as  critical  to  our  success,  and  we  rely  upon  trademark  and  copyright  law,  trade  secret
protection and confidentiality and/or license agreements with our employees, clients, partners and others to protect our proprietary rights. The steps taken by us to protect our
proprietary rights may not be adequate or third parties may infringe or misappropriate our copyrights, trademarks, trade secrets and similar proprietary rights. In addition, other
parties may assert infringement claims against us.

We are dependent on key personnel and need to hire additional qualified personnel in order for our business to succeed.

Our performance is substantially dependent on the performance of our senior management and key technical personnel. In particular, our success depends substantially on the
continued efforts of our senior management team, which currently is composed of a small number of individuals. The loss of the services of any of our executive officers, our
medical staff, our laboratory directors or other key employees could have a material adverse effect on our business, results of operations and our financial condition. Our future
success also depends on our continuing ability to attract and retain highly qualified managerial and technical personnel as we grow. Competition for such personnel is intense
and  we  may  not  be  able  to  retain  our  key  managerial  and  technical  employees  or  may  not  be  able  to  attract  and  retain  additional  highly  qualified  managerial  and  technical
personnel in the future. The inability to attract and retain the necessary managerial and technical personnel could have a material adverse effect upon our business, results of
operations and financial condition.

Additionally, our ability to retain existing clients for our specialized diagnostic services and attract new clients is dependent upon retaining existing sales representatives and
hiring and training new sales representatives, which is an expensive and time-consuming process. We face intense competition for qualified sales personnel and our inability to
hire or retain an adequate number of sales representatives could limit our ability to maintain or expand our business and increase sales. Even if we are able to increase our sales
force, our new sales personnel may not commit the necessary resources or provide sufficient high quality service and attention to effectively market and sell our services. If we
are  unable  to  maintain  and  expand  our  marketing  and  sales  networks  or  if  our  sales  personnel  do  not  perform  to  our  standards,  we  may  be  unable  to  maintain  or  grow  our
existing  business  and  our  results  of  operations  and  financial  condition  will  likely  suffer  accordingly.  If  a  sales  representative  ceases  employment,  we  risk  the  loss  of  client
goodwill  based  on  the  impairment  of  relationships  developed  between  the  sales  representative  and  the  healthcare  professionals  for  whom  the  sales  representative  was
responsible. This is particularly a risk if the representative goes to work for a competitor, as the healthcare professionals that are our clients may choose to use a competitor’s
services based on their relationship with our former sales representative.

Further,  non-compliant  activities  and  unlawful  conduct  by  sales  and  marketing  personnel  could  give  rise  to  significant  risks  under  the  AKS.  We  require  extensive,
comprehensive training of all sales and marketing personnel, but cannot guarantee that every staff member will comply with the training. Thus, in addition to the cost of training
sales and marketing personnel, we could face liability under the AKS for non-compliance by individuals engaged in prohibited sales and marketing activities.

Failure in our information technology systems could significantly increase testing turn-around time or billing processes and otherwise disrupt our operations.

Our laboratory operations depend, in part, on the continued performance of our information technology systems. Our information technology systems are potentially vulnerable
to physical or electronic break-ins, computer viruses and similar disruptions. Sustained system failures or interruption of our systems in one or more of our laboratory operations
could disrupt our ability to process laboratory requisitions, perform testing, provide test results in a timely manner and/or bill the appropriate party. Breaches with respect to
protected health information could result in violations of HIPAA, the Health Information Technology for Economic and Clinical Health Act, (“HITECH Act”), and analogous
state laws, and risk the imposition of significant fines and penalties. Failure of our information technology systems could adversely affect our business, results of operations and
financial condition.

Performance issues, service interruptions or price increases by our shipping carrier could adversely affect our business, results of operations and financial condition,
and harm our reputation and ability to provide our specialized diagnostic services on a timely basis

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Expedited, reliable shipping is essential to our operations. One of our marketing strategies entails highlighting the reliability of our point-to-point transport of patient samples.
We rely heavily on a single provider of transport services, FedEx Corporation (the “Carrier”) for reliable and secure point-to-point transport of patient samples to our laboratory
and enhanced tracking of these patient samples. Should the Carrier encounter delivery performance issues such as loss, damage or destruction of a sample, it may be difficult to
replace our patient samples in a timely manner and such occurrences may damage our reputation and lead to decreased demand for our services and increased cost and expense
to our business. In addition, any significant increase in shipping rates could adversely affect our operating margins and results of operations. Similarly, strikes, severe weather,
natural disasters or other service interruptions by delivery services we use would adversely affect our ability to receive and process patient samples on a timely basis. If the
Carrier or we were to terminate our relationship, we would be required to find another party to provide expedited, reliable point-to-point transport of our patient samples. There
are only a few other providers of such nationwide transport services, and there can be no assurance that we will be able to enter into arrangements with such other providers on
acceptable  terms,  if  at  all.  Finding  a  new  provider  of  transport  services  would  be  time-consuming  and  costly  and  result  in  delays  in  our  ability  to  provide  our  specialized
diagnostic services. Even if we were to enter into an arrangement with such provider, there can be no assurance that they will provide the same level of quality in transport
services currently provided to us by the Carrier. If the new provider does not provide the required quality and reliable transport services, it could adversely affect our business,
reputation, results of operations and financial condition.

We use biological and hazardous materials that require considerable expertise and expense for handling, storage or disposal and may result in claims against us

We work with hazardous materials, including chemicals, biological agents and compounds, blood samples and other human tissue that could be dangerous to human health and
safety or the environment. Our operations also produce hazardous and bio hazardous waste products. Federal, state and local laws and regulations govern the use, generation,
manufacture, storage, handling and disposal of these materials and wastes. Compliance with applicable environmental laws and regulations may be expensive, and current or
future environmental laws and regulations may impair business efforts. If we do not comply with applicable regulations, we may be subject to fines and penalties. In addition,
we  cannot  entirely  eliminate  the  risk  of  accidental  injury  or  contamination  from  these  materials  or  wastes.  Our  general  liability  insurance  and/or  workers’  compensation
insurance policy may not cover damages and fines arising from biological or hazardous waste exposure or contamination. Accordingly, in the event of contamination or injury,
we could be held liable for damages or penalized with fines in an amount exceeding our resources, and our operations could be suspended or otherwise adversely affected.

Risks Relating to Regulation

If we were required to conduct additional clinical trials prior to continuing to sell our current tests or launching any other tests we may develop, those trials could
result in delays or failure to obtain necessary regulatory approvals, which could harm our business.

In  the  event  that,  in  the  future,  the  FDA  begins  to  regulate  our  tests,  it  may  require  additional  pre-market  clinical  testing  prior  to  submitting  a  regulatory  notification  or
application for commercial sales. Such pre-market clinical testing could delay the commencement or completion of clinical testing, significantly increase our test development
costs,  delay  commercialization  of  any  future  tests,  and  interrupt  sales  of  our  current  tests.  Many  of  the  factors  that  may  cause  or  lead  to  a  delay  in  the  commencement  or
completion  of  clinical  trials  may  also  ultimately  lead  to  delay  or  denial  of  regulatory  clearance  or  approval.  The  commencement  of  clinical  trials  may  be  delayed  due  to
insufficient patient enrollment, which is a function of many factors, including the size of the patient population, the nature of the protocol, the proximity of patients to clinical
sites and the eligibility criteria for the clinical trial.

We may find it necessary to engage contract research organizations to perform data collection and analysis and other aspects of our clinical trials, which might increase the cost
and complexity of our trials. We may also depend on clinical investigators, medical institutions and contract research organizations to perform the trials. If these parties do not
successfully  carry  out  their  contractual  duties  or  obligations  or  meet  expected  deadlines,  or  if  the  quality,  completeness  or  accuracy  of  the  clinical  data  they  obtain  is
compromised due to the failure to adhere to our clinical protocols or for other reasons, our clinical trials may have to be extended, delayed or terminated. Many of these factors
would be beyond our control. We may not be able to enter into replacement arrangements without undue delays or considerable expenditures. If there are delays in testing or
approvals as a result of the failure to perform by third parties, our research and development costs would increase, and we may not be able to obtain regulatory clearance or
approval for our tests. In addition, we may not be able to establish or maintain relationships with these parties on favorable terms, if at all. Each of these outcomes would harm
our ability to market our tests and/or to achieve sustained profitability.

Proposed government regulation of LDTs may result in delays to launching certain laboratory tests and increase our costs to implement new tests.

We frequently develop diagnostic tests for clients that cannot currently be provided using test kits approved or cleared by the FDA. The FDA has been considering changes to
the way that it regulates these LDTs. Currently all LDTs are conducted and

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offered  in  accordance  with  the  CLIA,  and  individual  state  licensing  procedures.  The  FDA  has  published  a  draft  guidance  document  that  would  require  FDA  clearance  or
approval  of  a  subset  of  LDTs,  as  well  as  a  modified  approach  for  some  lower  risk  LDTs  that  may  require  FDA  oversight  short  of  the  full  premarket  approval  or  clearance
process.  Congress  may  enact  legislation  to  provide  a  regulatory  framework  for  the  FDA’s  role  with  regard  to  LDTs.  As  a  result,  there  is  a  risk  that  the  FDA’s  proposed
regulatory process could delay the offering of certain tests and result in additional validation costs and fees. There is also an associated risk for us that some tests currently
offered  might  become  subject  to  FDA  premarket  approval  or  clearance.  This  FDA  approval  or  clearance  process  may  be  time-consuming  and  costly,  with  no  guarantee  of
ultimate approval or clearance.

On July 31, 2014 the FDA issued a notification to Congress of the “Anticipated Details of the Draft Guidance for Industry, Food and Drug Administration Staff, and Clinical
Laboratories: Framework for Regulatory Oversight of Laboratory Developed Tests,” or the Draft LDT Guidance. As described in this notification, the FDA planned to provide
draft guidance to clinical laboratories that develop their own LDTs regarding how the FDA intends to regulate such laboratories under the Federal Food, Drug, and Cosmetic
Act. On October 3, 2014 the FDA issued the draft guidance to clinical laboratories. The regulatory framework will use a risk-based approach to enforce the FDA’s premarket
review requirements, and for high-risk tests, the framework may require laboratories to use FDA-approved tests, if available, rather than LDTs. If implemented, the framework
outlined in the Draft LDT Guidance may also require us to obtain premarket clearance or approval for certain of our LDTs. Implementation of this framework would include a
lengthy phase-in period ranging from two to nine years depending on the risk assessment rating of each particular test. The FDA provided an opportunity for public comment
through February 2015 and received numerous public comments in response to the Draft LDT Guidance. In January 2017 the FDA announced that it would not issue a final
guidance on the oversight of LDTs at the request of various stakeholders to allow for further public discussion on an appropriate oversight approach, and to give congressional
authorizing  committees  the  opportunity  to  develop  a  legislative  solution. At  the  same  time,  Congress,  the  FDA,  and  various  industry  stakeholders  have  worked  to  provide
recommendations for comprehensive reform of LDTs. Recently, Congress has submitted a legislative discussion draft, the Diagnostic Accuracy and Innovation Act (“DAIA”)
to  the  FDA  and  requested  technical  assistance  on  the  draft. FDA's  technical  assistance  consisted  of  recommendations  for  significant  changes  in  the  bill.  In  December  2018,
Congress released an updated bill, the Verifying Accurate Leading-edge IVCT Development (“VALID”) Act that is largely consistent with the FDA's technical assistance on
DAIA. However, it remains unknown whether Congress will enact legislation regulating LDTs and, if so, whether the legislation will be similar to the framework described in
the Draft LDT Guidance, or in the VALID act. This legislation and resulting FDA regulation may result in increased regulatory burdens for us to register and continue to offer
our tests or to develop and introduce new tests and may increase our costs. We do not yet know which of our tests would be classified as high-risk and would require a full FDA
approval. If such approval was required, we cannot be certain that our tests would obtain FDA approval or clearance.

If  the  FDA  and/or  congressional  authorizing  committees  begin  to  regulate  our  tests,  it  could  require  a  significant  volume  of  applications  with  the  FDA  and/or  document
responses  to  congressional  authorizing  committees  which  would  be  burdensome.  Furthermore,  FDA  and/or  congressional  authorizing  committees  could  take  a  long  time  to
review such applications and/or document responses if every laboratory in the country files a large volume of applications and/or document responses for each of their LDTs.

In November of 2017, CMS initiated a national coverage analysis for the use of Next Generation Sequencing “NGS” diagnostic tests for patients with advanced cancer. The
proposed decision memo was released and open to a public comment period. On March 16, 2018, CMS issued a final decision memorandum for NGS as a diagnostic laboratory
test and determined it to be reasonable and necessary and covered nationally, when performed in a CLIA-certified laboratory, when ordered by a treating physician and when all
of the following requirements are met: (a) the patient has either recurrent, relapsed, refractory, metastatic, or advanced stages III or IV cancer; (b) the patient has either not been
previously tested using the same NGS test for the same primary diagnosis of cancer or has had repeat testing using the same NGS test only when a new primary cancer diagnosis
is made by the treating physician; and (c) the patient has decided to seek further cancer treatment (e.g., therapeutic chemotherapy). CMS also determined that the diagnostic
laboratory test using NGS must have: FDA approval or clearance as a companion in vitro diagnostic; an FDA approved or cleared indication for use in that patient’s cancer; and
results provided to the treating physician for management of the patient using a report template to specify treatment options. These CMS changes to reimbursement for NGS
testing could directly affect our revenue for this test type.

Healthcare reform programs may impact our business and the pricing we receive for our services.

In March of 2010, health care reform legislation known as the “Patient Protection and Affordable Care Act,” also known as the ACA, was passed into law. The ACA also makes
changes  that  are  expected  to  significantly  impact  the  pharmaceutical  and  medical  device  industries  and  clinical  laboratories.  For  example,  the ACA  provided  that  effective
December 31, 2017, each medical device manufacturer must pay excise tax in an amount equal to 2.3% of the price for which such manufacturer sells its medical devices that
are listed with the FDA. Although the FDA issued Draft LDT Guidance that, if finalized, would regulate certain clinical laboratory tests that are developed and validated by a
laboratory for its own use, ("LDTs"), as medical devices, none of our LDTs such as our prostate cancer test are currently listed with the FDA. In 2018, however, Congress
passed an

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extension of a two-year moratorium on the Medical Device Excise Tax until December 31, 2019. The extension was retroactive, covering the time between January 1,2018 and
January 22, 2018 when the tax would have otherwise been in effect. We cannot assure you that the tax will not apply to services such as ours after the moratorium.

The  ACA  contains  several  provisions  that  seek  to  limit  Medicare  spending  in  the  future.  One  key  provision  in  the  ACA  is  the  establishment  of  “Accountable  Care
Organizations,” or (“ACOs”), under which hospitals and physicians are able to share savings that result from improved coordination of health care. We cannot predict how the
continued establishment and implementation of these new business models will impact our business. There is the possibility that value-based payment models, such as ACOs,
will drive down the utilization and/or reimbursement rates for our services. We may not be able to gain access into certain ACOs. These changes could have an adverse and
material impact on our operations.

The ACA provided for states to create health insurance “Marketplaces” where individuals can compare and enroll in Qualified Health Plans, (“QHPs”).  Individuals  with  an
income less than 400% of the federal poverty level that purchase insurance on a Marketplace may be eligible for federal subsidies to cover a portion of their health insurance
premium  costs  and  cost-sharing  of  co-insurance  or  co-pay  obligations.  Our  patients  may  be  enrolled  in  QHPs,  and  we  may  begin  to  submit  bills  to  QHPs  for  services  we
provide. The presence of federal funds in QHPs in the form of subsidies and cost-sharing may subject providers to heightened government scrutiny and enforcement, which
could significantly increase the cost of compliance and could materially impact our operations. For example, it is not clear whether the availability of these federal subsidies
classifies a QHP as a federal healthcare program, particularly for purposes of federal fraud and abuse laws. In letters published on October 30, 2013 and February 6, 2014, the
former  Secretary  of  the  Department  of  Health  &  Human  Services,  (“DHHS”),  Kathleen  Sebelius,  indicated  that  DHHS  does  not  consider  QHPs  to  be  federal  healthcare
programs.  However,  a  judge  may  not  agree  with  this  statement  by  Secretary  Sebelius,  and  other  government  regulators,  including,  but  not  limited  to  the  current  of  future
Secretary of the DHHS, may take a different position. For example, subsequent letters from U.S. Senator Charles Grassley to Secretary Sebelius and Attorney General Eric
Holder on November 7, 2013 and February 12, 2014 indicate that this issue remains an outstanding question. If QHPs are classified as federal healthcare programs, it could
significantly increase our costs of compliance.

In January 2017, Congress voted to adopt a budget resolution for fiscal year 2017, or the Budget Resolution, that authorizes the implementation of legislation that would repeal
portions of the ACA. Further, in January 2017, President Trump signed an Executive Order directing federal agencies with authorities and responsibilities under the ACA to
waive, defer, grant exemptions from, or delay the implementation of any provision of the ACA that would impose a fiscal or regulatory burden on states, individuals, healthcare
providers, health insurers, or manufacturers of pharmaceuticals or medical devices. In December of 2017, President Trump signed into law Public Law No. 115-97, which made
changes  to  the  tax  code  and  included,  among  other  things,  a  repeal  of  the ACA’s  penalties  for  the  individual  mandate,  a  provision  that  required  individuals  to  buy  health
insurance or pay a fine. On December 14, 2018 a federal district court judge in the Northern District of Texas ruled that Public Law No. 115-97 rendered the individual mandate
unconstitutional and further ruled that the rest of the ACA was inseverable from the individual mandate, rendering the ACA in its entirety invalid. As of January 2019, this
ruling  has  been  stayed  pending  the  outcome  of  an  appeal  to  the  U.S.  Fifth  Circuit  Court  of Appeals. Additionally,  the ACA  continues  to  be  challenged  in  other  lawsuits.
Congress  also  could  consider  subsequent  legislation  to  replace  elements  of  the  ACA  that  are  repealed  or  ruled  invalid.  Because  of  the  continued  uncertainty  about  the
implementation and constitutionality of the ACA, there can be no assurance at this time that the implementation (or repeal) of these provisions, or the ACA as a whole, will not
have a material adverse effect on our business.

Steps taken by government payers, such as Medicare and Medicaid to control the utilization and reimbursement of healthcare services, including esoteric testing may
diminish our net revenue.

We face efforts by government payers to reduce utilization as well as reimbursement for laboratory testing services. Changes in governmental reimbursement may result from
statutory and regulatory changes, prospective and/or retroactive rate adjustments, administrative rulings and other policy changes.

From time to time, legislative freezes and updates affect some of our tests that are reimbursed by the Medicare program under the Medicare Physician Fee Schedule, ("MPFS"),
or the Clinical Laboratory Fee Schedule, ("CLFS"). The MPFS is updated on an annual basis. In the past, the MPFS was updated using a prescribed statutory formula; (i.e., the
sustainable growth rate formula). The Medicare Access and CHIP Reauthorization Act of 2015, ("MACRA"), repealed the previous statutory formula and specified new annual
conversion factors for calendar years 2015 and beyond. If the new annual conversion factor results in negative reimbursement in future years, the resulting decrease in payment
may adversely affect our revenue, business, operating results, financial condition and prospects.

In addition, recent laws have made changes to Medicare reimbursement for our tests that are reimbursed under the CLFS, many of which have already gone into effect. In June
2016, CMS published the Clinical Laboratory Fee CLFS final rule entitled “Medicare Program: Medicare Clinical Diagnostic Laboratory Tests Payment System” (CMS-1621-
F). The final rule provides regulations to implement the provisions of the Protecting Access to Medicare Act of 2014, ("PAMA"), which was signed into

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law in April 2014. Under the final rule, laboratories, including physician office laboratories, are required to report private payer rate and volume data if they:

•

•

Have $12,500 or more in Medicare revenues from laboratory services on the CLFS and

They receive more than 50 percent of their Medicare revenues from CLFS or PFS during a data collection period.

Tests that meet the criteria for being considered new advanced tests will be paid at actual list charge during an initial period of three calendar quarters. Once the initial period is
over, payment for new, advanced tests would be based on the weighted median private payer rate reported by the single laboratory that performs the new ADLT. Advanced tests
are tests furnished by only one laboratory that include a unique algorithm and, at a minimum, are an analysis of RNA, DNA or proteins or are cleared or approved by the FDA.

Applicable laboratories must report data that includes the payment rate (reflecting all discounts, rebates, coupons and other price concessions) and the volume of each test that
was paid by each private payer (including health insurance issuers, group health plans, Medicare Advantage plans and Medicaid managed care organizations). The definition of
“applicable” laboratory may exclude certain types of laboratories that generally receive more favorable pricing than other laboratories, and thus the make-up of laboratories
reporting pricing data to CMS under the proposed rule may result in lower overall pricing data. Beginning in 2017, the Medicare payment rate for each clinical diagnostic lab
test is equal to the weighted median amount for the test from the most recent data collection period. For example, applicable laboratories were required to collect private payer
data from January 1, 2016 through June 30, 2016 and report it to CMS by March 31, 2017. The new Medicare CLFS rates (based on weighted median private payer rates) were
released in November 2017 and were effective on January 1, 2018. For the years 2017 through 2019, the amount of reduction in the Medicare rate (if any) shall not exceed 10
percent from the prior year’s rate. From January 1, 2019 through June 30, 2019, applicable laboratories are required to collect private payer data and report it to CMS by March
31, 2020. The new Medicare CLFS rates (based on weighted median private payer rates) will be released in November 2020 and will become effective January 1, 2021. For the
years 2020 through 2022, any reduction in the Medicare rate shall not exceed 15 percent from the prior year’s rate. It is too early to predict the impact on reimbursement for our
tests reimbursed under the CLFS, though we believe the government’s goal is to reduce Medicare program payments for CLFS tests. Specifically, CMS projected that the effect
of this rule on the Medicare program will be a savings of $360 million in program payments for CLFS tests furnished in FY 2017, and a savings of $5.14 billion over 10 years,
although  estimates  by  the  Congressional  Budget  Office  have  been  significantly  less.  CMS  also  finalized  its  proposal  that  a  laboratory’s  failure  to  comply  with  reporting
obligations, or a laboratory that makes a misrepresentation or omission in reporting required information, could lead to liability under the Civil Monetary Penalties Law.

Also under PAMA, CMS is required to adopt temporary billing codes to identify new tests and new advanced diagnostic laboratory tests that have been cleared or approved by
the FDA. For an existing test that is cleared or approved by the FDA and for which Medicare payment is made, CMS is required to assign a unique billing code if one has not
already been assigned by the agency. Further, PAMA provides special payment status to “advanced diagnostic laboratory tests,” ("ADLTs"), to allow such ADLTs to be paid
using their actual list charge amount during a certain time frame. We cannot determine at this time the full impact of the new law on our business, financial condition and results
of operations.

CMS also adopts regulations and policies, from time to time, revising, limiting or excluding coverage or reimbursement for certain of the tests that we perform. Likewise, many
state governments are under budget pressures and are also considering reductions to their Medicaid fees. Further, Medicare, Medicaid and other third party payers audit for
overutilization  of  billed  services.  Even  though  all  tests  performed  by  us  are  ordered  by  our  clients,  who  are  responsible  for  establishing  the  medical  necessity  for  the  tests
ordered, we may be subject to recoupment of payments, as the recipient of the payments for such tests, in the event that a third party payer such as CMS determines that the tests
failed  to  meet  all  applicable  criteria  for  payment.  When  third  party  payers  like  CMS  revise  their  coverage  regulations  or  policies,  our  costs  generally  increase  due  to  the
complexity  of  complying  with  additional  administrative  requirements.  Furthermore,  Medicaid  reimbursement  and  regulations  vary  by  state. Accordingly,  we  are  subject  to
varying administrative and billing regulations, which also increase the complexity of servicing such programs and our administrative costs. Finally, state budget pressures have
encouraged  states  to  consider  several  courses  that  may  impact  our  business,  such  as  delaying  payments,  restricting  coverage  eligibility,  service  coverage  restrictions  and
imposing taxes on our services.

In certain jurisdictions including Alaska, Arkansas, Arizona, California, Hawaii, Indiana, Idaho, Kentucky, Missouri, Montana, Nevada, North Carolina, North Dakota, Ohio,
Oregon,  South  Carolina,  South  Dakota,  Utah,  Virginia,  Washington,  West  Virginia  and  Wyoming,  Palmetto  GBA  administers  the  Molecular  Diagnostic  Services  Program,
("MolDx"),  and  establishes  coverage  and  reimbursement  for  certain  molecular  diagnostic  tests,  including  many  of  our  tests.  To  obtain  Medicare  coverage  for  a  molecular
diagnostic  test  (FDA  approved  or  LDT),  laboratories  must  apply  for  and  obtain  a  unique  test  identifier  or  what  is  known  as  a  “Z”  code.  For  newly  developed  tests  or  for
established tests that have not been validated for clinical and analytical validity and clinical utility, laboratories must submit a detailed dossier of clinical data to substantiate
that the test meets Medicare’s requirements for coverage. We have received favorable coverage for many of our molecular tests, however we have also received non-coverage
determinations  for  many  newer  tests.  The  field  of  molecular  diagnostics  is  evolving  very  rapidly,  and  clinical  studies  on  many  new  tests  are  still  underway.  We  cannot  be
assured that some of our molecular tests will

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ever be covered services by Medicare, nor can we determine when the medical literature will meet the standard for coverage that Medicare administrative contractors have set.

In recent years, Medicare has encouraged beneficiaries to participate in managed care programs, known as “Medicare Advantage” programs, and has encouraged beneficiaries
from the traditional fee-for-service Medicare program to switch to Medicare Advantage programs. This has resulted in rapid growth of health insurance and managed care plans
offering Medicare Advantage programs and growth in Medicare beneficiary enrollment in these programs. Also in recent years, many states have increasingly mandated that
Medicaid beneficiaries enroll in managed care arrangements. If these efforts continue to be successful, we may experience a further shift of traditional Medicare and Medicaid
fee-for-service beneficiaries to managed care programs. As a result, we would be required to contract with those private managed care programs in order to be reimbursed for
services provided to their Medicare and Medicaid members. There can be no assurance that we will be successful in entering into agreements with these managed care programs
at rates of payment similar to those we realize from our non-managed care lines of business.

Effective  January  1,  2018  CMS  implemented  an  additional  exception  to  the  laboratory  date  of  service  rules.  Prior  to  2018,  CMS’  14-day  rule  prevented  reference  and
independent laboratories such as ours from billing Medicare directly for clinical laboratory tests or the technical component of pathology services if, among other things, the
tests were ordered less than 14 days following an outpatient's discharge from the hospital. Instead, we would seek reimbursement from the hospital and the hospital would bill
Medicare. Effective January 1, 2018, certain molecular pathology tests and advanced diagnostic laboratory tests ("ADLTs") that previously had to be billed or could be billed
by the hospital are now required to be billed by the performing laboratory if certain requirements are met, although CMS has indicated it will exercise enforcement discretion
until July 1, 2019. Since our client-bill pricing is typically higher for Molecular testing than the Medicare fee schedule, we anticipate a reduction in revenue from this policy
change. Under the MolDx program there are many policies that limit reimbursement on certain tests based on diagnosis codes, and for certain tests there is no reimbursement
regardless of the patient’s condition.

We expect the initiatives described above to continue and, if they do, to reduce reimbursements for clinical laboratory services, to impose more stringent cost controls on clinical
laboratory  services  and  to  reduce  utilization  of  clinical  laboratory  services.  These  efforts,  including  changes  in  law  or  regulations  that  may  occur  in  the  future,  may  each
individually or collectively have a material adverse impact on our business, results of operations, financial condition and prospects.

Changes in regulations, payer policies or contracting arrangements with payers or changes in  other  laws,  regulations  or  policies  may  adversely  affect  coverage  or
reimbursement for our specialized diagnostic services, which may decrease our revenues and adversely affect our results of operations and financial condition.

Governmental payers, as well as private insurers and private payers, have implemented and will continue to implement measures to control the cost, utilization and delivery of
healthcare services, including clinical laboratory and pathology services. Congress and federal agencies, such as CMS, have, from time to time, implemented changes to laws
and  regulations  governing  healthcare  service  providers,  including  specialized  diagnostic  service  providers.  These  changes  have  adversely  affected  and  may  in  the  future
adversely affect coverage for our services. We also believe that healthcare professionals may not use our services if third-party payers do not provide adequate coverage and
reimbursement  for  them.  These  changes  in  federal,  state,  local  and  third-party  payer  regulations  or  policies  may  decrease  our  revenues  and  adversely  affect  our  results  of
operations and our financial condition. We will continue to be a non-contracting provider until such time as we enter into contracts with third-party payers with whom we are not
currently contracted until such time as we enter into contracts with such third-party payers. Because a portion of our revenues is from third-party payers with whom we are not
currently contracted, it is likely that we will be required to make positive or negative adjustments to accounting estimates with respect to contractual allowances in the future,
which may adversely affect our results of operations, our credibility with financial analysts and investors, and our stock price.

Failure  to  comply  with  environmental,  health  and  safety  laws  and  regulations,  including  the  federal  Occupational  Safety  and  Health Administration Act,  and  the
Needlestick Safety and Prevention Act could result in fines and penalties and loss of licensure, and have a material adverse effect upon our business.

We  are  subject  to  licensing  and  regulation  under  federal,  state  and  local  laws  and  regulations  relating  to  the  protection  of  the  environment  and  human  health  and  safety,
including laws and regulations relating to the handling, transportation and disposal of medical specimens, infectious and hazardous waste and radioactive materials, as well as
regulations relating to the safety and health of laboratory employees. The federal Occupational Safety and Health Administration has established extensive requirements relating
to workplace safety for health care employers, including clinical laboratories, whose workers may be exposed to blood-borne pathogens such as HIV and the hepatitis B virus.
These  requirements,  among  other  things,  require  work  practice  controls,  protective  clothing  and  equipment,  training,  medical  follow-up,  vaccinations  and  other  measures
designed to minimize exposure to, and transmission of, blood-borne pathogens. In addition, the Needlestick Safety and Prevention Act requires, among other things, that we
include in our safety programs the evaluation and use of engineering controls such as safety needles, if found to be effective at reducing the risk of needlestick injuries in the
workplace.

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Failure  to  comply  with  such  federal,  state  and  local  laws  and  regulations  could  subject  us  to  denial  of  the  right  to  conduct  business,  fines,  criminal  penalties  and/or  other
enforcement actions, any of which could have a material adverse effect on our business. In addition, compliance with future legislation could impose additional requirements for
us, which may be costly.

Our net revenue will be diminished if payers do not adequately cover or reimburse our services.

There  has  been  and  will  continue  to  be  significant  efforts  by  both  federal  and  state  agencies  to  reduce  costs  in  government  healthcare  programs  and  otherwise  implement
government control of healthcare costs. In addition, private payers continually seek ways to reduce and control overall healthcare costs, and increasing emphasis on managed
care in the United States will continue to put pressure on the pricing of healthcare services. Uncertainty exists as to the coverage and reimbursement status of new applications
and services. Third-party payers, including governmental payers such as Medicare and private payers, are scrutinizing new medical products and services and may not cover or
may limit coverage and the level of reimbursement for our services. Third-party insurance coverage may not be available to patients for any of our existing tests or for tests we
discover and develop, and a substantial portion of the testing for which we bill our hospital and laboratory clients is ultimately paid by third-party payers. Any pricing pressure
exerted by these third party payers on our clients may, in turn, be exerted by our clients on us. If government and other third-party payers do not provide adequate coverage and
reimbursement for our tests, it could adversely affect our operating results, cash flows and/or our financial condition.

Third party billing is extremely complicated and results in significant additional costs to us.

Billing for laboratory services is extremely complicated. Depending on the billing arrangement and applicable laws, we must bill various payers, such as patients, insurance
companies, Medicare, Medicaid, doctors and employer groups, hospitals and other laboratories, all of which have different billing requirements. Additionally, we undertake
internal audits to evaluate compliance with applicable laws and regulations as well as internal compliance policies and procedures. Insurance companies and government payers
such as Medicare and Medicaid also impose routine external audits to evaluate payments, which adds further complexity to the billing process.

Among others, the primary factors which complicate our billing practices are:

•

•

•

•

•

pricing differences between our fee schedules and the reimbursement rates of the payers;

changes in payer rules or contracts;

disputes with payers as to the party who is responsible for payment;

disparity in coverage and information requirements among various carriers; and

differing pre-authorization requirements across insurance carriers

We incur significant additional costs as a result of our participation in the Medicare and Medicaid programs, as billing and reimbursement for clinical laboratory services are
subject to considerable and complex federal and state regulations. The additional costs we expect to incur include those related to: (i) complexity added to our billing processes
and systems; (ii) training and education of our employees and clients; (iii) implementing compliance procedures and oversight; (iv) collections and legal costs; and (v) costs
associated  with,  among  other  factors,  challenging  coverage  and  payment  denials  and  providing  patients  with  information  regarding  claims  processing  and  services,  such  as
advance beneficiary notices.

Our operations are subject to strict laws prohibiting fraudulent billing and other abuse, and our failure to comply with such laws could result in substantial penalties.

Of particular importance to our operations is ensuring compliance with federal and state laws prohibiting fraudulent billing and the retention of overpayments. In particular, if
we fail to comply with federal and state documentation, coding and billing rules, we could be subject to liability under the federal False Claims Act, including civil penalties,
loss of licenses and exclusion from the Medicare and Medicaid programs. The False Claims Act prohibits individuals and companies from knowingly submitting false claims
for payments to, or improperly retaining overpayments from, the government.

If an entity is determined to have violated the federal False Claims Act, it may be required to pay up to three times the actual damages sustained by the government, plus civil
penalties of between $11,181 and $22,363 for each separate false claim. Further, False Claims Act liability may lead to exclusion from participation in Medicare, Medicaid and
other federal healthcare programs. There are a number of potential bases for liability under the federal False Claims Act. For example, liability arises when an entity knowingly
submits, or causes another to submit, a claim for reimbursement to the federal government for a service which was not provided or which did not qualify for reimbursement.
Submitting a claim with reckless disregard or deliberate ignorance of its truth or falsity could also result in liability under the False Claims Act. Following enactment of the
ACA, knowing retention of overpayments is also considered a false claim and could lead to liability under the False Claims Act.

The False Claims Act’s “whistleblower” or “qui tam” provisions are being used with more frequency to challenge the reimbursement practices of providers and suppliers. Those
provisions  allow  a  private  individual  to  bring  an  action  on  behalf  of  the  government  alleging  that  the  defendant  has  submitted  false  claims  for  payment  to  the  federal
government. The government

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must decide whether to intervene in the lawsuit and whether to prosecute the case. If it declines to do so, the individual may pursue the case alone, although the government
must be kept apprised of the progress of the lawsuit. Whether or not the federal government intervenes in the case, it will receive the majority of any recovery. The successful
qui tam relator who brought the case is entitled to a portion of the proceeds and his or her attorneys’ fees and costs. In addition, various states have enacted laws modeled after
the federal False Claims Act, which prohibit submitting false claims for payment to the state or, in some states, to other commercial payers. If we fail to comply with federal and
state documentation, coding, and billing rules, we could be subject to criminal liability through a variety of federal and state criminal statutes.

Government investigations of clinical laboratories have been ongoing for a number of years and are expected to continue in the future. When we submit bills for our services to
third-party  payers,  we  must  follow  complex  documentation,  coding  and  billing  rules  which  are  based  on  federal  and  state  laws,  rules  and  regulations,  various  government
publications,  and  on  industry  practice.  A  large  number  of  laboratories  have  entered  into  substantial  settlements  with  the  federal  and  state  governments  for  alleged
noncompliance under these laws and rules. Private payers have also brought civil actions against laboratories which have resulted in substantial judgments. Failure to follow
these  rules  could  result  in  potential  civil  liability  under  the  False  Claims Act,  under  which  extensive  financial  penalties  can  be  imposed.  It  could  further  result  in  criminal
liability  under  various  federal  and  state  criminal  statutes.  For  example,  there  are  various  state  and  federal  laws  and  rules  regulating  laboratory  billing  practices,  such  as
prohibiting a clinical laboratory from charging a higher price for tests ordered by a physician and provided by a third-party (anti-markup rules) as well as requiring a laboratory
performing certain laboratory tests to directly bill Medicare instead of the ordering provider (direct billing rules).

We submit thousands of claims for Medicare and other payments and we cannot guarantee that there have not been errors in our claims, While we maintain a robust compliance
program that includes consistent, detailed review of our documentation, and coding and billing practices, the rules are frequently vague, complex, and continually changing and
we cannot assure that governmental investigators, private insurers or private whistleblowers will not challenge our practices. Such a challenge could result in a material adverse
effect on our business.

The failure to comply with significant government regulation and laboratory operations may subject us to liability, penalties or limitation of operations.

We are subject to extensive state and federal regulatory oversight. Specifically, our laboratories must satisfy federal requirements under the CLIA to maintain the appropriate
CLIA Certificate for all testing performed at the lab. Additionally, most states have adopted various laws and regulation setting standards for laboratories performing clinical
laboratory testing and requiring laboratories to obtain and maintain a state laboratory license before the laboratory is authorized to perform testing. These state licensure laws
address a host of requirements and often include permissible and prohibited practices involving digital health, including but not limited to telehealth and telepathology.

Upon periodic inspection or survey, our laboratory locations may be found to be non-compliant with CLIA requirements or with applicable licensure or certification laws. The
sanctions for failure to comply with CLIA, state licensure requirements, or other applicable laws and regulations could include the suspension, revocation, or limitation of the
right to perform clinical laboratory services or receive compensation for those services, as well as the requirement to enter into a corrective action plan to monitor compliance,
and the imposition of civil or criminal penalties or administrative fines. In addition, any new legislation or regulation or the application of existing laws and regulations in ways
that we have not anticipated could have a material adverse effect on our business, results of operations and financial condition.

Existing  federal  laws  governing  Medicare  and  Medicaid,  as  well  as  some  other  state  and  federal  laws,  also  regulate  certain  aspects  of  the  relationship  between  healthcare
providers,  including  clinical  laboratories,  and  their  referral  sources,  including  physicians,  hospitals  and  other  laboratories.  Certain  of  these  laws,  including  the  federal  “anti-
kickback  law”  and  the  federal  physician  self-referral  law  (the  “Stark  Law”)  contain  extremely  broad  proscriptions.  Violation  of  these  laws  may  result  in  criminal  penalties,
exclusion from participation in the Medicare, Medicaid, and other federal healthcare programs, repayment of all services tied to any impermissible referrals, and significant
civil  monetary  penalties,  as  well  as  False  Claims Act  liability.  We  seek  to  structure  our  arrangements  with  physicians  and  other  clients  to  be  in  compliance  with  the  anti-
kickback  laws,  Stark  Law  and  similar  state  laws,  and  to  keep  up-to-date  on  developments  concerning  their  application  by  various  means,  including  consultation  with  legal
counsel  and  review  of  the  annual  Work  Plan  by  the  Office  of  the  Inspector  General  (“OIG”)  identifying  targeted  issues.  We  cannot  guarantee,  however,  that  government
authorities will not take a contrary view and impose civil monetary penalties and exclude us based on our arrangements with physicians and other clients.

The federal Civil Monetary Penalties Law, ("federal CMP Law"), imposes civil monetary penalties and exclusion from Medicare and Medicaid programs on any person who
offers or transfers remuneration to any patient who is a Medicare or Medicaid beneficiary, when the person knows or should know that the remuneration is likely to induce the
patient to receive medical services from a particular provider. The federal CMP Law applies, among other things, to many kinds of inducements or benefits provided to patients,
including complimentary items, services or transportation that are of more than a nominal value. We have structured our operations and provision of services to patients in a
manner that we believe complies with the law and its interpretation by government authorities. We cannot guarantee, however, that government authorities will not take a

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contrary view and impose civil monetary penalties and exclude us for past or present practices related to patient incentive, coordination of care and need-based programs.

Furthermore, HIPAA, the HITECH Act, (as implemented through HIPAA's Privacy and Security Rules) and similar state laws contain provisions that require the electronic
exchange of health information, such as claims submission and receipt of remittances, using standard transactions and code sets, which we refer to as "Standards," and regulate
the use and disclosure of patient records and other PHI. These provisions, which address security and confidentiality of patient information as well as the administrative aspects
of claims handling, have very broad applicability and govern many healthcare providers, including physicians and clinical laboratories. Although we believe we are in material
compliance with the Standards, the Privacy and Security Rules, and applicable state privacy and security laws, a failure to comply with these laws could have a material adverse
effect on our business, results of operations and our financial condition and could subject us to liability. Additionally, while there is no private right of action under HIPAA,
state Attorneys  General  may  bring  an  action  against  a  covered  entity,  such  as  us,  for  a  violation  of  HIPAA,  and  the  national  Office  for  Civil  Rights  can  impose  fines  and
penalties.

The failure to comply with physician self-referral laws may subject us to liability, penalties or limitation of operations

We  are  subject  to  the  federal  Stark  Law,  as  well  as  similar  state  statutes  and  regulations,  which  prohibit  payments  for  certain  health  care  services,  which  are  referred  to  as
designated  health  services  (“DHS”),  rendered  as  a  result  of  referrals  by  physicians  to  DHS  entities  with  which  the  physicians  (or  their  immediate  family  members)  have  a
financial relationship. A “financial relationship” includes both an ownership interest and/or a compensation arrangement with a physician, both direct and indirect, and DHS
includes, but is not limited to, laboratory services. The Stark Law prohibits an entity that receives a prohibited DHS referral from seeking payment from Medicare for any DHS
services performed as a result of such a referral, unless an arrangement is carefully structured to satisfy every requirement of a regulatory exception. The Stark Law is a strict
liability statute, and thus any technical violation requires repayment of all “tainted” referrals, regardless of the intent, unless an exception applies. Penalties for violating the
Stark Law may include the denial of payment to an entity for the impermissible provision of DHS, the requirement to refund any amounts collected in violation of the Stark
Law, and civil monetary penalties of up to $24,748 for each violation and $164,992 for each circumvention arrangement or scheme. The amounts may be further increased by
civil  monetary  penalty  increases  imposed  by  the  Bipartisan  Budget Act  of  2018.  Other  implications  of  a  Stark  Law  violation  may  include  exclusion  from  Medicare  and
Medicaid programs, and potential False Claims Act liability, including via “qui tam” action.

Further, many states have promulgated self-referral laws and regulations similar to the federal Stark Law, but these vary significantly based on the state. In addition to services
reimbursed by Medicaid or government payers, often these state laws and regulations can encompass services reimbursed by private payers as well. Penalties for violating state
self-referral laws and regulations vary based on the state, but often include civil penalties, exclusion from Medicaid, and loss of licenses.

Our financial arrangements with physicians are governed by the federal Stark Law, and we rely on certain exceptions to the Stark Law with respect to such relationships. While
we believe that our financial relationships with physicians and referral practices are in compliance with applicable laws and regulations, we cannot guarantee that government
authorities would agree. If we are found by the government to be in violation of the Stark Law, we could be subject to significant penalties, including fines as specified above,
exclusion from participation in government and private payer programs and requirements to refund amounts previously received from government. Further, as our operations
expand  into  new  states  and  jurisdictions,  we  must  continually  evaluate  whether  our  relationships  with  physicians  comply  with  that  jurisdiction’s  laws.  This  may  require
structural and organizational modifications to our relationships with physicians which could adversely affect our results of operations and financial condition.

The failure to comply with Anti-Kickback laws may subject us to liability, penalties or limitation of operations

We are subject to the federal Anti-Kickback Statute, ("AKS") and similar state statutes and regulations, which prohibit the offer, payment, solicitation or receipt of any form of
remuneration  in  return  for  referring,  ordering,  leasing,  purchasing  or  arranging  for  or  recommending  the  ordering,  purchasing  or  leasing  of  items  or  services  payable  by
Medicare, Medicaid or any other federally funded healthcare program. The AKS defines remuneration to include anything of value, in cash or in kind, and thus can implicate
financial  relationships  including  payments  not  commensurate  with  fair  market  value,  such  as  in  the  form  of  space,  equipment  leases,  professional  or  technical  services  or
anything else of value.

The AKS is an “intent-based” statute, meaning that a violation occurs when one or both parties intend the remuneration to be in exchange for or to induce referrals. In 2010, the
ACA, amended the intent requirement of the AKS. A person or entity no longer needs to have actual knowledge of the statute or specific intent to violate it. In addition, the
ACA provides that the government may assert that a claim including items or services resulting from a violation of the AKS constitutes a false or fraudulent claim for purposes
of the federal False Claims Act.

There  are  a  number  of  statutory  exceptions  and  regulatory  safe  harbors  protecting  certain  common  activities  from  prosecution  or  other  regulatory  sanctions;  however,  the
exceptions and safe harbors are drawn narrowly, and practices that do not fit squarely within an exception or safe harbor may be subject to scrutiny.  Violations of the AKS may
result in substantial civil or

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criminal penalties, including criminal fines of up to $100,000, imprisonment of up to ten years, civil penalties under the federal CMP Law of up to $100,000 for each violation,
plus three times the remuneration involved, civil penalties under the federal False Claims Act of a minimum of $11,181 and a maximum of $22,363 for each claim submitted,
plus  three  times  the  amounts  paid  for  such  claims  and  exclusion  from  participation  in  the  Medicare  and  Medicaid  programs.  If  we  face  these  penalties  or  the  participation
exclusion, it could significantly reduce our revenues and could have a material adverse effect on our business.

Further,  most  states  have  adopted  similar  anti-kickback  laws  prohibiting  the  offer,  payment,  solicitation  or  receipt  of  remuneration  in  exchange  for  referrals,  and  typically
impose criminal and civil penalties as well as loss of licenses. Some of these state laws apply to items and services paid for by private payers as well as by government payers.
In  addition,  many  states  have  adopted  laws  prohibiting  the  splitting  or  sharing  of  fees  between  physicians  and  non-physicians,  as  well  as  between  treating  physicians  and
referral sources. We believe our arrangements with physicians comply with the AKS, and state anti-kickback and fee splitting laws of the states in which we operate, however, if
government regulatory authorities were to disagree, we could be subject to civil and criminal penalties, and be required to restructure or terminate our contractual and other
arrangements with physicians. This could result in a loss of revenue and have a material adverse effect on our business.

Some states have also adopted laws prohibiting the corporate practice of medicine, or prohibiting business corporations from employing physicians or engaging in activities
considered to be the “practice of medicine.” In these states, we rely on service agreements with physicians and/or professional associations owned by physicians, to perform
needed professional pathology services. We cannot assure you that a physician or physician’s professional organization will not seek to terminate an agreement with us on any
basis, nor can we assure you that governmental authorities in those states will not seek termination of these arrangements on the basis of state laws prohibiting the corporate
practice of medicine.

A failure to comply with governmental payer regulations could result in our being excluded from participation in Medicare, Medicaid or other governmental payer
programs.

Tests  which  are  reimbursed  by  Medicare  and  other  Government  payers  (for  example,  State  Medicaid  programs)  accounted  for  approximately  15%,  14%  and  15%  of  our
revenues  for  the  years  ended  December  31,  2018,  2017  and  2016,  respectively.  The  Medicare  program  imposes  extensive  and  detailed  requirements  on  diagnostic  service
providers, including, but not limited to, rules that govern how we structure our relationships with physicians, how and when we submit claims for reimbursement and how we
provide specialized diagnostic laboratory services. Further, we are prohibited from contracting with any individuals or entities who have been excluded from participation in
Medicare  or  Medicaid  and  are  listed  on  the  OIG’s  List  of  Excluded  Individuals  and  Entities  List  ("LEIE")  or  in  the  System  for Award  Management,  which  includes  the
previously independent Government Services Administration's Excluded Parties List System ("GSA-EPLS"). Contracting with excluded individuals or entities, such as hiring an
excluded person or contracting with an excluded vendor, can result in significant penalties.

Our failure to comply with applicable Medicare, Medicaid and other governmental payer rules could result in our inability to participate in a governmental payer program, an
obligation to repay funds already paid to us for services performed, civil monetary penalties, criminal penalties, False Claims Act liability and/or limitations on the operational
function of our laboratory. If we were unable to receive reimbursement under a governmental payer program, a substantial portion of our revenues would be lost, which would
adversely affect our results of operations and financial condition.

Failure to comply with the HIPAA Privacy, Security and Breach Notification Regulations may increase our operational costs.

The HIPAA privacy and security regulations establish comprehensive federal standards with respect to the uses and disclosures of PHI by certain entities including health plans
and health care providers, and set standards to protect the confidentiality, integrity and availability of electronic medical records. The regulations establish a complex regulatory
framework governing the use and disclosure of PHI, including, for example, the circumstances under which uses and disclosures of PHI are permitted or required without a
specific  authorization  by  the  patient;  a  patient’s  right  to  access,  amend  and  receive  an  accounting  of  certain  disclosures  of  PHI;  the  content  of  notices  of  privacy  practices
describing how PHI is used and disclosed and individuals’ rights with respect to their PHI; and implementation of administrative, technical and physical safeguards to protect
privacy and security of PHI. The federal privacy regulations restrict our ability to use or disclose certain individually identifiable patient health information, without patient
authorization, for purposes other than payment, treatment or health care operations (as defined by HIPAA), except for disclosures for various public policy purposes and other
permitted purposes outlined in the privacy regulations. The HIPAA privacy and security regulations do not supersede state laws that may be more stringent; therefore, we are
required to comply with both federal privacy and security regulations and varying state privacy and security laws and regulations.

The HIPAA privacy and security regulations also require healthcare providers like us to notify affected individuals, the Secretary of the U.S. Department of Health and Human
Services, and in some cases, the media, when PHI has been "breached," as defined by HIPAA. Many states have similar breach notification laws. In the event of a breach, we
could incur substantial operational and financial costs related to mitigation and remediation, including preparation and delivery of notices to affected individuals. Additionally,
HIPAA, and its implementing regulations provide for significant civil fines, criminal penalties, and other sanctions for failure to comply with the privacy, security, and breach
notification rules, including for wrongful or

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impermissible use or disclosure of PHI. Although the HIPAA statute and regulations do not expressly provide for a private right of action for damages, we could incur damages
under state laws to private parties for the wrongful or impermissible use or disclosure of confidential health information or other private personal information. Additionally,
HIPAA allows state Attorneys General to bring an action against a covered entity, such as us, for a violation of HIPAA. We insure some of our risk with respect to HIPAA
security breaches, but operational costs and penalties associated with HIPAA breaches easily could exceed our insured limits.

We are subject to security risks which could harm our operations.

HIPAA imposes additional requirements, restrictions and penalties on covered entities and their business associates to, among other things, deter breaches of security. As a
result, required preventative and remedial actions, along with the aforementioned reporting requirements, and sanctions for a breach are stringent. Our electronic health records
system is periodically modified to meet applicable security standards. Despite the implementation of various security measures by us, our infrastructure may be vulnerable to
computer viruses, break-ins and other disruptive problems inadvertently introduced by authorized users such as employees and clients, or purposefully targeted by hackers and
other cybercriminals which could lead to interruption, delays or cessation in service to our clients. Further, such incidents, whether electronic or physical, could jeopardize the
security  of  confidential  information,  including  PHI  and  other  sensitive  information  stored  in  our  computer  systems  related  to  clients,  patients,  and  other  parties  connected
through us, which may deter potential clients and give rise to uncertain liability to parties whose security or privacy has been infringed. A significant security breach could
result in fines, loss of clients, damage to our reputation, direct damages, costs of repair and detection, costs to remedy the breach, government penalties, and other expenses. We
insure  some  of  our  risk  with  respect  to  security  breaches  but  the  occurrence  of  any  of  the  foregoing  events  could  have  a  material  adverse  effect  on  our  business,  results  of
operations and our financial condition.

Risks Relating to Our Common Stock

We currently do not expect to pay any cash dividends and the price of our stock may not appreciate.

We  do  not  anticipate  paying  dividends  on  our  common  stock  in  the  foreseeable  future.  Rather,  we  plan  to  retain  earnings,  if  any,  for  the  operation  and  expansion  of  our
business. If we do not pay dividends, the price of our common stock must appreciate for you to recognize a gain on your investment upon sale. This appreciation may not occur.

We may become involved in securities class action litigation that could divert management’s attention and harm our business.

The  stock  markets  have  from  time  to  time  experienced  significant  price  and  volume  fluctuations  that  have  affected  the  market  prices  for  the  common  stock  of  diagnostic
companies. These broad market fluctuations may cause the market price of our common stock to decline. In the past, securities class action litigation has often been brought
against a company following a decline in the market price of its securities. This risk is especially relevant for us because clinical laboratory service companies have experienced
significant  stock  price  volatility  in  recent  years.  We  may  become  involved  in  this  type  of  litigation  in  the  future.  Litigation  often  is  expensive  and  diverts  management’s
attention and resources, which could adversely affect our business.

If any securities analyst downgrades our common stock or our sector, the price of our common stock could be negatively affected.

Securities  analysts  may  publish  reports  about  us  or  our  industry  containing  information  about  us  that  may  affect  the  trading  price  of  our  common  stock.  If  a  securities  or
industry analyst downgrades the outlook for our common stock or one of our competitors’ stocks or chooses to terminate coverage of our common stock, the trading price of
our common stock may be negatively affected.

The price of our common stock may fluctuate significantly.

The price of our common stock has been, and is likely to continue to be, volatile, which means that it could decline substantially within a short period of time. The price of our
common stock could fluctuate significantly for many reasons including the following:

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future announcements concerning us or our competitors;

regulatory developments and enforcement actions bearing on advertising, marketing or sales;

reports and recommendations of analysts and whether or not we meet the milestones and metrics set forth in such reports; gaining or losing large customers or managed
care plans;

introduction of new products or services and related insurance coverage;

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•

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acquisition or loss of significant manufacturers, distributors or suppliers or an inability to obtain sufficient quantities of materials needed to provide our services;

quarterly variations in operating results;

business acquisitions or divestitures;

changes in the regulation of Laboratory Developed Tests (“LDTs”);

changes in governmental or third-party reimbursement practices and rates; and fluctuations in the economy, political events or general market conditions.

In  addition,  stock  markets  in  general  and  the  market  for  shares  of  health  care  stocks  in  particular,  have  experienced  extreme  price  and  volume  fluctuations  in  recent  years,
fluctuations that frequently have been unrelated to the operating performance of the affected companies. These broad market fluctuations may adversely affect the market price
of our common stock. The market price of our common stock could decline below its current price and the market price of our shares may fluctuate significantly in the future.
These fluctuations may be unrelated to our performance.

ITEM 1B. UNRESOLVED STAFF COMMENTS

None

ITEM 2. PROPERTIES

We operate an international network of laboratories. Our corporate office and most of our laboratory facilities are leased except 43,448 square feet of our Carlsbad, California
facility.  These  leases  expire  at  various  dates  through  2023.    We  believe  that  these  locations  are  sufficient  to  meet  our  needs  at  existing  volume  levels  and  that,  if  needed,
additional space will be available at a reasonable cost.

The following table summarizes our facilities by type and location:

Location
Carlsbad, California
Aliso Viejo, California
Fort Myers, Florida
Houston, Texas
Geneva (Rolle), Switzerland
Nashville, Tennessee
Tampa, Florida
Singapore
Fresno, California
Atlanta, Georgia
Plantation, Florida

Purpose
Laboratory, and administrative offices
Laboratory, and administrative offices
Corporate headquarters and laboratory
Laboratory
Laboratory
Laboratory
Laboratory
Laboratory
Laboratory
Laboratory
Courier office

Square Footage
105,066 
96,917 
56,889 
32,757 
7,976 
7,806 
5,875 
2,861 
2,541 
1,190 
240 

Our Switzerland and Singapore laboratories support our Pharma Services segment exclusively; all other locations support both segments of our business. For further financial
information about our segments, see Note R to our Consolidated Financial Statements included in this Annual Report.

ITEM 3. LEGAL PROCEEDINGS

From time to time the Company is engaged in legal proceedings that arise in the ordinary course of business. The Company believes that any resulting liability from these
proceedings will not, either individually or in the aggregate have a material adverse effect on our consolidated financial position, results of operations, or cash flows.

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Legal Matters

NEOGENOMICS, INC.

The  Company  is  involved  in  ongoing  litigation  with  Health  Discovery  Corporation  (“HDC”)  regarding  the  use  of  certain  licensed  technology  under  a  Master  License
Agreement (“MLA”) dated January 6, 2012 between the Company and HDC. As required under the MLA, the parties are required to submit such matters in dispute under the
MLA  to  binding  arbitration. An  arbitration  hearing  took  place  in  December  2018,  where  the  Company  vigorously  defended  its  legal  rights  and  remedies  pertaining  to  this
licensing dispute. The arbitration panel has not yet rendered a decision, and the parties are engaged in required post-hearing procedures as requested by the arbitration panel.
The  Company  does  not  believe,  based  on  currently  available  information,  that  the  outcome  of  this  matter  will  have  a  material  adverse  effect  on  the  Company's  financial
condition.

ITEM 4. MINE SAFETY DISCLOSURES

Not applicable.

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NEOGENOMICS, INC.

PART II

ITEM 5. MARKET FOR THE REGISTRANTS COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND ISSUER PURCHASES OF EQUITY
SECURITIES

Market Information

Our common stock is listed on the NASDAQ Capital Market under the symbol “NEO”.

Holders of Common Stock

As  of  February  22,  2019,  there  were  504  stockholders  of  record  of  our  common  stock.  The  number  of  record  holders  does  not  include  beneficial  owners  of  common  stock
whose shares are held in the names of banks, brokers, nominees or other fiduciaries.

Dividends

We have never declared or paid cash dividends on our common stock. We intend to retain all future earnings to finance operations and future growth and, therefore, we do not
anticipate paying any cash dividends in the foreseeable future.  Our financing arrangements contain certain restrictions on our ability to pay dividends on our common stock.

Equity Compensation Plan Information

The following table summarizes the securities authorized for issuance under equity compensation plans as of December 31, 2018:

Plan Category

Equity compensation plans approved by security holders:

Amended and Restated Equity Incentive Plan
(“Equity Incentive Plan”)
Employee Stock Purchase Plan (“ESPP”)

Total

Number of securities to be issued
upon exercise of outstanding
options, warrants and rights

Weighted average exercise price
of outstanding options, warrants
and rights

Number of securities remaining
available for future issuance under
equity compensation plans

6,839,417  $

— 

6,839,417  $

7.63 
N/A

7.63 

3,298,645  (a)
505,084  (b)

3,803,729 

a.

b.

The  Company’s  Equity  Incentive  Plan  was  amended,  restated  and  subsequently  approved  by  a  majority  of  shareholders  on  December  21,  2015  and  amended  and
subsequently  approved  by  a  majority  of  shareholders  on  May  25,  2017.    The  most  recent  amendment  increased  the  maximum  aggregate  number  of  shares  of  the
Company’s common stock reserved and available for issuance under the Amended Plan to 18,650,000.
The  Company's  Employee  Stock  Purchase  Plan  was  amended,  restated  and  subsequently  approved  by  a  majority  of shareholders  on  June  6,  2013  and  amended  and
subsequently  approved  by  a  majority  of  shareholders  on  May  25,  2017  and  June  1,  2018. The most recent amendment increased the maximum aggregate number of
shares reserved and available for issuance under the Plan to 1,500,000.

Currently, the Company’s Equity Incentive Plan, as amended on May 25, 2017 and the Company’s ESPP, as amended on June 1, 2018, are the only equity compensation plans
in effect.

Recent Sales of Unregistered Securities

On December 10, 2018 we issued 1,000,000 shares of common stock to the shareholders of Genesis Acquisition Holding Corp. in connection with the acquisition of Genoptix.
See Notes E and P to our Consolidated Financial Statements included in this Annual Report.

In August  2017,  the  Company  acquired  a  customer  list  from Ascend  Genomics  in  exchange  for  450,000  shares  of  common  stock.  See  Notes  F  and  P  to  our  Consolidated
Financial Statements included in this Annual Report.

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NEOGENOMICS, INC.

Comparison of Cumulative Five Year Total Return

We have presented below the cumulative total return to our stockholders of $100 during the period from December 31, 2013, through December 31, 2018 in comparison to the
cumulative return on the S&P 500 Index and a customized peer group of six publicly traded companies during that same period. The peer group is made up of Cancer Genetics,
Inc.,  Enzo  Biochem,  Inc.,  Genomic  Health,  Inc.,  Laboratory  Corporation  of America  Holdings,  Myriad  Genetics,  Inc.,  and  Quest  Diagnostics,  Inc.  Several  of  our  closest
competitors are part of large pharmaceutical or other multi-national firms, or are privately held and, as such, we are unable to get financial information for them.

The  results  assume  that  $100  (with  reinvestment  of  all  dividends)  was  invested  in  our  common  stock,  the  index  and  in  the  peer  group  and  its  relative  performance  tracked
through December 31, 2018. The comparisons are based on historical data and are not indicative of, nor intended to forecast, the future performance of our common stock. The
performance graph set forth above shall not be deemed incorporated by reference into any filing by us under the Securities Act or the Exchange Act except to the extent that we
specifically incorporate such information by reference therein.

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NEOGENOMICS, INC.

ITEM 6. SELECTED FINANCIAL DATA

The following is a summary of our historical consolidated financial data for the periods ended and at the dates indicated below. You are encouraged to read this information
together  with  our  audited  consolidated  financial  statements  and  the  related  footnotes  and  “Management’s  Discussion  and Analysis  of  Financial  Condition  and  Results  of
Operations” included elsewhere in this Annual Report.

The historical consolidated financial data for the years ended December 31, 2018, 2017 and 2016 (Statement of Operations Data and Other Cash Data) has been derived from
our audited consolidated financial statements, which are included elsewhere in this Annual Report. The historical consolidated financial data for the years ended December 31,
2015 and 2014 has been derived from our audited consolidated financial statements, which are not included in this Annual Report.

The historical consolidated financial data as of December 31, 2018 and 2017 (Balance Sheet Data) has been derived from our audited consolidated financial statements, which
are included elsewhere in this Annual Report. The historical consolidated financial data (Balance Sheet Data) as of December 31, 2016, 2015 and 2014 has been derived from
our audited consolidated financial statements, which are not included in this Annual Report.

We believe that the comparability of our financial results between the periods presented in the table below is significantly impacted by factors which are more fully described in
“Management’s Discussion and Analysis of Financial Condition and Results of Operations” and the Consolidated Financial Statements and the notes thereto included elsewhere
in this Annual Report.

Statement of Operations Data:

Net revenue
Cost of revenue

Gross margin

Operating expenses

Income (loss) from operations
Interest and other (income) expense
Income tax expense (benefit)

Net income (loss)

Deemed dividends on preferred stock
Amortization of preferred stock beneficial conversion feature
Gain on redemption of preferred stock

Net income (loss) due to common stockholders

Net income (loss) per common share – Basic
Net income (loss) per common share – Diluted

Other Cash Data:

Net cash – operating activities
Net cash – investing activities
Net cash – financing activities

Years Ended December 31,

2018 (4)

2017 (3) 
(as adjusted)

2016 
(as adjusted)

2015 (1)(5)

2014 (2)(5)

(In thousands, except per share data)

$

$

$
$

$
$
$

276,741  $
149,476 

127,265 

117,225 

10,040 
6,216 
1,184 

2,640 
10,198 
(4,571)
(9,075)

240,251  $
138,295 

101,956 

99,054 

2,902 
5,552 
(2,254)

(396)
3,645 
6,902 
— 

231,808  $
133,704 

99,802  $
56,046 

98,104 

95,949 

2,155 
9,998 
(1,701)

(6,142)
18,011 
6,663 
— 

43,756 

49,391 

(5,635)
(1,146)
(1,954)

(2,535)
40 
82 
— 

6,088  $

(10,943) $

(30,816) $

(2,657) $

0.07  $
0.07  $

44,786  $
(139,687) $
91,959  $

(0.14) $
(0.14) $

18,037  $
(13,690) $
(4,095) $

(0.40) $
(0.40) $

21,477  $
(6,501) $
(25,871) $

(0.04) $
(0.04) $

6,393  $
(75,155) $
58,493  $

87,069 
46,355 

40,714 

38,496 

2,218 
929 
157 

1,132 
— 
— 
— 

1,132 

0.02 
0.02 

9,450 
(9,602)
29,007 

1.
2.
3.
4.
5.

Reflects the acquisition of Clarient in December 2015.
Reflects the acquisition of Path Logic in July 2014.
Reflects the sale of Path Logic on August 2017.
Reflects the acquisition of Genoptix in December 2018.
Does not reflect the impact of the adoption of ASU 2014-09, Revenue from Contracts with Customers (Topic 606), which was adopted in the first quarter of 2018.

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NEOGENOMICS, INC.

Balance Sheet Data:
Current assets
Property and equipment
Intangible assets
Goodwill
Other assets

Total assets

Current liabilities
Long-term liabilities

Total liabilities
Series A Redeemable Convertible Preferred Stock
Stockholders’ equity

Total liabilities preferred stock and stockholders’ equity

Working Capital

2018 (5)

2017 (4) 
(as adjusted)

As of December 31,

2016 
(as adjusted)

(In thousands)

2015 (1)(3)(6)

2014 (2)(6)

$

$

$

$

$

103,668  $
60,888 
140,029 
197,892 
2,538 

505,015  $

85,875  $
36,504 
74,165 
147,019 
891 

344,454  $

79,398  $
34,036 
77,064 
147,019 
206 

337,723  $

60,925  $

36,471  $

39,789  $

123,647 

184,572 
— 
320,443 

103,406 

139,877 
32,615 
171,962 

112,746 

152,535 
22,873 
162,315 

82,360  $
34,577 
87,800 
146,421 
129 

351,287  $

40,058  $
73,117 

113,175 
28,602 
209,510 

505,015  $

344,454  $

337,723  $

351,287  $

42,743  $

49,404  $

39,609  $

42,302  $

58,742 
15,082 
4,212 
2,929 
141 

81,106 

14,623 
6,078 

20,701 
— 
60,405 

81,106 

44,119 

1.
2.
3.
4.
5.
6.

Reflects the acquisition of Clarient in December 2015.
Reflects the acquisition of Path Logic in July 2014.
Reflects the adoption of ASU 2015-17, Income Taxes: Balance Sheet Classification of Deferred Taxes.
Reflects the sale of Path Logic on August 1, 2017.
Reflects the acquisition of Genoptix in December 2018.
Does not reflect the impact of the adoption of ASU 2014-09, Revenue from Contracts with Customers (Topic 606), which was adopted in the first quarter of 2018.

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NEOGENOMICS, INC.

ITEM 7. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Introduction

The following discussion and analysis should be read in conjunction with the Consolidated Financial Statements and the Notes thereto included in this Annual Report on Form
10-K. The information contained below includes statements of management’s beliefs, expectations, hopes, goals and plans that, if not historical, are forward-looking statements
subject  to  certain  risks  and  uncertainties  that  could  cause  actual  results  to  differ  materially  from  those  anticipated  in  the  forward-looking  statements.  For  a  discussion  on
forward-looking statements, see the information set forth in the Introductory Note to this Annual Report under the caption “Forward Looking Statements”, which information is
incorporated herein by reference.

Our Company

NeoGenomics, Inc. is a high-complexity CLIA-certified clinical laboratory that specializes in cancer genetics diagnostic testing and pharma services. The Company's testing
services include  cytogenetics,  fluorescence  in-situ  hybridization  (FISH),  flow  cytometry,  immunohistochemistry,  anatomic  pathology  and  molecular  genetic  testing. 
Headquartered in Fort Myers, FL, NeoGenomics has laboratories in Aliso Viejo, Carlsbad and Fresno, CA; Tampa and Fort Myers, FL; Houston, TX; Nashville, TN; Rolle,
Switzerland;  and  Singapore.    NeoGenomics  services  the  needs  of  pathologists,  oncologists,  pharmaceutical  companies,  academic  centers,  other  clinicians,  and  hospitals
throughout the United States, Europe, and Asia.

2018 Overview and Highlights

•

•

•

•

•

We increased revenues by 15.2% compared to 2017, including an increase in Clinical revenue of 13.5% and an increase in Pharma revenue of 28.4%.

We completed the acquisition of Genoptix in December 2018 for approximately $125 million in cash and one million shares of NeoGenomics common stock.

We  continued  our  international  expansion  with  the  opening  of  a  laboratory  in  Singapore  and  the  announcement  of  a  global  strategic  affiliation  with
Pharmaceutical Product Development, LLC (“PPD”).

We redeemed 100% of our Series A Redeemable Convertible preferred stock.

We completed a $135 million equity offering.

Company Outlook

We have developed a company-wide focus for 2019, which includes the following three critical success factors:

•

•

•

To strengthen our world-class culture by seeking feedback from employees on ways to innovate and grow our business. We will focus on employee engagement
and inclusion through collaboration forums, team dialogue and programs to reward teams.

To provide uncompromising quality and service through company-wide leadership, coaching and employee engagement initiatives. Our laboratory teams will
focus on quality by improving the Corrective and Preventative Actions (“CAPA”) process and streamlining and simplifying processes.

To pursue exceptional service and growth through renewed focus on improving the customer experience through the launch of innovative assays, informatics
products and companion diagnostics as well as enhanced educational programs. We will continue to pursue market share gains in both our Clinical and Pharma
Services businesses.

These  critical  success  factors  have  been  communicated  throughout  our  Company.  We  have  structured  departmental  goals  around  these  factors  and  have  created  employee
incentive plans in which every employee will have a meaningful incentive for our success.  

As we focus on profitable growth, we will continue to pursue large purchasing group contracts.  In 2018, we were successful in gaining market share by entering into contracts
with managed care organizations and large hospital groups, which will be part of our strategy as we continue to gain scale.  In addition, our molecular testing menu remains a
strong selling point as it enables us to offer clients a “one stop shop” where they can send all of their oncology testing rather than using multiple labs.

Innovation and changes in science and technology will lead to new therapeutic and diagnostic tests.  Our Company strives to lead in innovation with the launch of new assays,
informatics products, research projects, educational programs and companion

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NEOGENOMICS, INC.

diagnostics.  We will continue to work with pharmaceutical clients on their clinical trials and will work to be on the leading edge of developments in the field of oncology.  

We believe lower cost and increased value of testing is extremely important to the healthcare industry and creates a competitive advantage for our company.  We will invest in
information technology, automation and best practices to continually improve our processes and drive down the cost of testing.  We will continue to expand our test menu and
remain  at  the  forefront  of  the  ongoing  revolution  in  cancer  related  genetic  and  molecular  testing  to  achieve  our  vision  of  becoming  the  world’s  leading  cancer  testing  and
information company.

We have significantly expanded our capacity, especially in the Pharma Services area of our business.  The opening of a laboratory in Switzerland in 2017 and in Singapore in
2018 as well as the recent expansion of our Houston laboratory will allow us to better serve our existing Pharma Services clients and obtain new business in the U.S. and across
Europe and Asia. We expect our strong growth momentum as well as our added capacity to create opportunities for improved quality and revenue growth.

Regulatory Environment

The FDA has been considering changes which may include increased regulation of Laboratory Developed Tests (“LDTs”).  These changes could impact the laboratory testing
industry  and  our  business,  as  further  described  the  discussion  of  Government  Regulations  in  Item  1.    In  October  2014,  the  FDA  announced  its  proposed  framework  and
timetable.  However, at this point the FDA has not released a proposed rule, and it is anticipated that there would be a comment period related to such a significant change.  The
FDA has indicated that there will be a “phase in” period that in some instances will take as long as nine years.  On January 13, 2017 the FDA released a discussion paper in
which  the  FDA  said  that  they  “hope  that  it  advances  public  discussion  on  future  LDT  oversight”.    The  paper  does  not  represent  formal  FDA  policy,  nor  is  it
enforceable.    Recently,  Congress  has  submitted  a  legislative  discussion  draft,  the  Diagnostic Accuracy  and  Innovation Act  (“DAIA”),  to  the  FDA  and  requested  technical
assistance  on  the  draft. In  December  2018,  Congress  released  an  updated  bill,  the  Verifying  Accurate  Leading-edge  IVCT  Development  (“VALID”)  Act  that  is  largely
consistent with FDA’s technical assistance on DAIA. However, it remains unknown whether Congress will enact legislation regulating LDTs and, if so, whether the legislation
will be similar to the framework described in the Draft LDT Guidance, or in the VALID Act.   NeoGenomics is a member of the American Clinical Laboratory Association
(“ACLA”), which has been in active discussions with the FDA and Congress regarding FDA oversight of LDT’s.  At this point we cannot predict the outcome of this issue, or if
there will be any changes to current rules and regulations.    

We closely monitor changes in legislation and take specific actions to identify and estimate the impact of changes in legislation whenever possible as regulatory changes can
affect reimbursement for clinical laboratory services. We do not anticipate significant changes to our clinical revenue in 2018 based on known changes in legislation.

Operating Segments

The Company reports its activities in two operating segments the Clinical Services Segment and the Pharma Services Segment. We have presented the financial information
reviewed by the Chief Operating Decision Maker (“CODM”) including revenues, cost of revenue and gross margin for each of our operating segments. The segment
information presented in these financial statements has been conformed to present segments on this revised basis for all prior periods.  Assets are not presented at the segment
level as that information is not used by the CODM.  

Clinical Services

Our Clinical Services segment includes the cancer testing services we offer to community-based pathologists, hospitals, academic centers, and oncology groups and is designed
to  be  a  natural  extension  of,  and  complementary  to,  the  services  that  they  perform  within  their  own  practices.  We  believe  our  relationship  as  a  non-competitive  partner  to
community-based  pathology  practices,  hospital  pathology  labs  and  academic  centers  empowers  them  to  expand  their  breadth  of  testing  and  provide  a  menu  of  services  that
matches or exceeds the level of service found in any center of excellence around the world.

Pharma Services

Our  Pharma  Services  segment  supports  pharmaceutical  firms  in  their  drug  development  programs  by  supporting  various  clinical  trials.    This  portion  of  our  business  often
involves working with the pharmaceutical firms (sponsors) on study design as well as performing the testing required to validate assays in development and support of Phase I -
III clinical trials.  Our medical team often advises the sponsor and works closely with them as specimens are received from enrolled sites.  We also work on

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developing tests that will be used as part of a companion diagnostic to determine patients’ response to a particular drug.  As studies unfold, our clinical trials team reports the
data and often provide key analysis and insights back to the sponsors.

Our Pharma Services segment provides comprehensive testing services in support of our pharmaceutical clients’ oncology programs from discovery to commercialization.  In
biomarker  discovery,  our  aim  is  to  help  our  customers  discover  the  right  content.    We  help  our  customers  develop  a  biomarker  hypothesis  by  recommending  an  optimal
platform for molecular screening and backing our discovery tools with the informatics to capture meaningful data.  In other pre and non-clinical work, we can use our platforms
to characterize markers of interest.   Moving from discovery to development, we help our customers refine their biomarker strategy and, if applicable, develop a companion
diagnostic pathway using the optimal technology for large-scale clinical trial testing.

Whether serving as the single contract research organization or partnering with one, our Pharma Services group provides significant technical expertise working closely with
our customers to support each stage of clinical trial development.  Each trial we support comes with rapid turnaround time, dedicated project management and quality assurance
oversight. We have experience in supporting submissions to the Federal Drug Administration for companion diagnostics and our Pharma Services strategy is focused on helping
bring more effective oncology treatments to market through providing world class laboratory services in oncology to key pharmaceutical companies in the industry.

Critical Accounting Policies

The  preparation  of  financial  statements  in  conformity  with  United  States  generally  accepted  accounting  principles  ("GAAP")  requires  management  to  make  estimates  and
assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported
amounts of revenues and expenses during the reporting period. Actual results could differ  from  those  estimates.  Our  management  routinely  makes  judgments  and  estimates
about the effects of matters that are inherently uncertain. For a complete description of our significant accounting policies, see Note B to our Consolidated Financial Statements.

Our critical accounting policies are those where we have made difficult, subjective or complex judgments in making estimates, and/or where these estimates can significantly
impact our financial results under different assumptions and conditions. Our critical accounting policies are:

•

•

•

•

•

Revenue Recognition

Accounts Receivable

Intangible Assets

Stock Based Compensation

Deferred taxes

Revenue Recognition

We  adopted Accounting  Standards  Codification  ("ASC")  606, Revenues  from  Contracts  with  Customers,  on  January  1,  2018  using  a  full  retrospective  method  of  adoption.
Under  this  method,  the  Company  has  restated  its  results  for  each  prior  reporting  period  presented  as  if ASC  606  had  been  effective  for  those  periods.  The  adoption  of  this
standard required us to implement new revenue policies, procedures and internal controls related to revenue recognition. In addition, the adoption resulted in enhanced financial
statement disclosures surrounding the nature, amount, timing and uncertainty of revenue and cash flows arising from contracts with customers.

The  new  standard  impacted  each  of  our  two  reportable  segments  differently  due  to  the  transactional  nature  of  the  Clinical  Services  segment  versus  the  generally  long-term
nature of our Pharma Services segment contracts. The specific effect on our reportable segments is explained further in Note B to our Consolidated Financial Statements.

Clinical Services Revenue

The  Company’s  specialized  diagnostic  services  are  performed  based  on  a  written  test  requisition  form  or  electronic  equivalent.  The  performance  obligation  is  satisfied  and
revenues are recognized once the diagnostic services have been performed and the results have been delivered to the ordering physician. These diagnostic services are billed to
various  payers,  including  Medicare,  commercial  insurance  companies,  other  directly  billed  healthcare  institutions  such  as  hospitals  and  clinics,  and  individuals.  Revenue  is
recorded for all payers based on the amount expected to be collected, which considers implicit price

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concessions.  Implicit  price  concessions  represent  differences  between  amounts  billed  and  the  estimated  consideration  the  Company  expects  to  receive  based  on  negotiated
discounts, historical collection experience and other anticipated adjustments, including anticipated payer denials. Collection of consideration the Company expects to receive
typically occurs within 30 to 60 days of billing for commercial insurance, Medicare and other governmental and self-pay payers and within 60 to 90 days of billing for client
payers.

The following table reflects our estimate of the breakdown of net revenue by type of payer for the fiscal years ended December 31, 2018, 2017, and 2016:

Medicare and other government
Commercial insurance
Client direct billing

Total

2018

2017 
(as adjusted)

2016 
(as adjusted)

15 %
17 %
68 %

100 %

14  %
17  %
69  %

100  %

15  %
25  %
60  %

100  %

Our proportion of client direct billing has increased over the years shown above, as more payers, including private commercial insurances and Medicare Advantage plans are
practicing “consolidated payment” or “bundled payment” models where they pay the hospitals a lump sum, which is intended to include laboratory testing.  This reflects an
increase in the amount of risk sharing that CMS and other private payers are encouraging providers such as hospital systems to undertake. We had previously anticipated a
gradual increase in the percentage of client direct billing over the coming years; however, on January 1, 2018 Medicare made a significant change to what is known as the “14-
day rule”. The net result of this rule change is that certain molecular tests that were previously billed to clients, are now once again eligible to be billed directly to the Medicare
program. As a result, our Medicare direct bill revenue increased slightly in 2018 and our client direct bill revenue decreased slightly.

Pharma Services Revenue

The  Company’s  Pharma  Services  segment  generally  enters  into  contracts  with  pharmaceutical  and  biotech  customers  as  well  as  other  Contract  Research  Organizations
("CROs") to provide research and clinical trial services ranging in duration from one month to several years. The Company records revenue on a unit-of-service basis based on
number of units completed and the total expected contract value. The total expected contract value is estimated based on historical experience of total contracted units compared
to realized units as well as known factors on a specific contract-by-contract basis. Certain contracts include upfront fees, final settlement amounts or billing milestones that may
not align with the completion of performance obligations. The value of these upfront fees or final settlement amounts is usually recognized over time based on the number of
units completed, which aligns with the progress of the Company towards fulfilling its obligations under the contract. The Company also enters into other contracts, such as
validation studies, for which the sole deliverable is a final report that is sent to sponsors at the completion of contracted activities. For these contracts, revenue is recognized at a
point in time upon delivery of the final report to the sponsor. Any contracts that contain multiple performance obligations and include both units-of-service and point in time
deliverables are accounted for as separate performance obligations and revenue is recognized as previously disclosed. The Company negotiates billing schedules and payment
terms on a contract-by-contract basis. While the contract terms generally provide for payments based on a unit-of-service arrangement, the billing schedules, payment terms and
related cash payments may not align with the performance of services and, as such, may not correspond to revenue recognized in any given period.

Amounts collected in advance of services being provided are deferred as contract liabilities on the balance sheet. The associated revenue is recognized and the contract liability
is reduced as the contracted services are subsequently performed. Contract assets are established for revenue that has been recognized but not yet billed. These contract assets
are reduced once the customer is invoiced and a corresponding account receivable is recorded. Additionally, certain costs to obtain contracts, primarily for sales commissions,
are  capitalized  when  incurred  and  are  amortized  over  the  term  of  the  contract. Amounts  capitalized  for  contracts  with  an  initial  contract  term  of  twelve  months  or  less  are
classified as current assets and all others are classified as non-current assets.

Most contracts are terminable by the customer, either immediately or according to advance notice terms specified within the contracts.  All contracts require payment of fees to
the Company for services rendered through the date of termination and may require payment for subsequent services necessary to conclude the study or close out the contract.

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NEOGENOMICS, INC.

Trade Accounts Receivable

Accounts  receivable  are  reported  for  all  clinical  services  payers  based  on  the  amount  expected  to  be  collected,  which  considers  implicit  price  concessions.  Implicit  price
concessions represent differences between amounts billed and the estimated consideration the Company expects to receive based on negotiated discounts, historical collection
experience and other anticipated adjustments, including anticipated payer denials.

For Pharma Services, the Company negotiates billing schedules and payment terms on a contract-by-contract basis which often includes payments based on certain milestones
being achieved. Receivables are generally reported over time based on the number of units completed, which aligns with the progress of the Company towards fulfilling its
obligations under the contract.

Days Sales Outstanding (“DSO”) decreased from 91 days at December 31, 2017 to 77 days at December 31, 2018.  These consolidated results include a decrease in Clinical
Services DSO’s from 87 days to 76 days as well as a decrease in Pharma Services DSO’s from 115 days to 82. The decreases are the result of improved billing practices in both
segments as well as the resolution of aged receivables in Pharma.

Intangible Assets

We review our long-lived assets for recoverability if events or changes in circumstances indicate the assets may be impaired.  Impairment exists when the carrying amount of
the asset exceeds fair value.

Genoptix

As a result of the acquisition of Genoptix in December 2018, we recorded an estimated $71.8 million in intangible assets comprised of $56.6 million in customer relationships
which  will  be  amortized  over  a  fifteen-year  period,  $0.7  million  related  to  the  Genoptix  trade  name  which  we  will  amortize  over  a  one-year  period,  and  $14.6  million  in
trademarks which are indefinite-lived assets. The amortization expense for these assets is included in general and administrative expense.

Clarient

As a result of the acquisition of Clarient in December 2015, we recorded $84.0 million in intangible assets comprised of $81.0 million in customer relationships which is being
amortized over a fifteen-year period and $3.0 million related to the Clarient trade name which was amortized over a two-year period.  The amortization expense for these assets
is included in general and administrative expense.

Purchase of Third-Party Customer List  

In August 2017, we acquired a customer list and recorded $4.1 million in intangible assets comprised of customer relationships which is being amortized over a fifteen-year
period. The amortization expense for this asset is included in general and administrative expense.

Stock Based Compensation

We recognize compensation costs for all share-based payment awards made to employees, non-employee contracted physicians and directors based upon the awards’ initial
grant-date fair value. For stock options, we use a trinomial lattice option-pricing model to estimate the fair value of stock option awards, and recognize compensation cost on a
straight-line basis over the awards’ requisite service periods. The Company’s periodic expense is adjusted for actual forfeitures.

See Note B and Note L in the Consolidated Financial Statements included in this Annual Report for more information regarding the assumptions used in our valuation of stock-
based compensation.

Deferred Taxes

Our accounting for deferred tax consequences represents our best estimate of future events that can be appropriately reflected in accounting estimates. The factors included in
the analysis are historical and projected future taxable income including expectations of pending contracts and evolving business practices of our industry. Changes in existing
tax laws, regulations, rates and future operating results may impact the amount of deferred tax liabilities and deferred tax assets over time.

Management assesses the available positive and negative evidence to estimate if sufficient future taxable income will be generated to use the existing deferred tax assets.  

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NEOGENOMICS, INC.

As of December 31, 2018, the Company determined that sufficient positive evidence did not exist to conclude that it is more likely than not that the net operating losses being
generated by the Company's Switzerland and Singapore operations would be able to be utilized in future periods and has therefore established a full valuation allowance against
the deferred tax assets generated by these jurisdictions. As of December 31, 2017, the Company did not record a valuation allowance as management determined that sufficient
positive evidence existed to conclude that it was more likely than not that deferred tax assets were realizable.

Results of Operations for the year ended December 31, 2018 as compared with the year ended December 31, 2017

The following table presents the condensed consolidated statements of operations as a percentage of revenue:

NET REVENUE
Cost of revenue

GROSS PROFIT
OPERATING EXPENSES:
General and administrative
Research and development
Sales and marketing
Loss on sale of Path Logic

Total operating expenses

INCOME FROM OPERATIONS
Interest expense, net

Net income (loss) before income taxes
Income tax expense (benefit)

NET INCOME (LOSS)

Revenue

For the years ended
December 31,

2018

2017 (as adjusted)

100.0  %
54.0 %

46.0 %

30.7 %
1.1  %
10.6 %
— %

42.4 %

3.6  %
2.3  %

1.3  %
0.4  %

0.9  %

100.0  %
57.6 %

42.4 %

29.3 %
1.5  %
10.0 %
0.4  %

41.2 %

1.2  %
2.3  %

(1.1)%
(0.9)%

(0.2)%

Clinical and Pharma Services revenue for the periods presented are as follows ($ in thousands):

Net revenues:
Clinical Services
Pharma Services

Total Revenue

For the Years Ended December 31,

2018

2017 (as adjusted)

% Change

$

$

241,873  $
34,868 

276,741  $

213,097 
27,154 

240,251 

13.5 %
28.4 %

15.2 %

Consolidated revenues increased $36.5 million,  or 15.2%, year-over-year.  Growth in our clinical segment year-over-year, was $28.8 million,  or 13.5%. Testing volumes also
increased in our clinical segment by approximately 11.4% year-over-year. The increases in revenue and volume were due to strong, balanced growth with continued growth in
all modalities. We continue to negotiate managed care and group purchasing contracts to increase our in-network coverage, which should improve reimbursement rates and
facilitate the addition of new accounts. 

Pharma  Services  revenue  increased $7.7  million,  or 28.4%,  year-over-year.    In  addition,  our  backlog  of  signed  contracts  has  continued  to  grow  from $68.7  million  as  of
December 31, 2017 to $98.9 million as of December 31, 2018.  We define backlog as the stated amount of signed contracts less dormant contracts with no activity for twelve
months, contingencies and cancellations.  The recently completed expansion of our Pharma facility in Houston, Texas, provides additional capacity to manage this backlog. We
expect this backlog to result in higher revenues in future years.   

We  also  expect  to  achieve  accelerating  revenue  growth  in  our  Pharma  Services  segment  due  to  our  growing  international  presence. In  addition  to  our  laboratory  in  Rolle,
Switzerland, we announced a global strategic partnership with PPD in 2018, and continued our international expansion including the opening of a laboratory in Singapore.

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The following table shows clinical revenue, cost of revenue, requisitions received and tests performed for the years ended December 31, 2018  and  2017.    This  data  excludes
tests performed for Pharma customers and tests performed by Path Logic, which was sold on August 1, 2017.  Testing revenue and cost of revenue are presented in thousands
below:

Requisitions received (cases)
Number of tests performed
Average number of tests/requisition

Total clinical genetic testing revenue
Average revenue/requisition
Average revenue/test

Cost of revenue
Average cost/requisition
Average cost/test

2018

December 31,

2017 (as adjusted)

% Change

439,597 
749,902 
1.71 

241,873  $
550  $
323  $

128,296  $
292  $
171  $

394,520 
657,394 
1.67 

209,584 
531 
319 

117,838 
299 
179 

$
$
$

$
$
$

11.4 %
14.1 %
2.4  %

15.4 %
3.6  %
1.2  %

8.9  %
(2.3)%
(4.5)%

We continue to realize growth in our clinical testing revenue which we believe is the direct result of our efforts to innovate by developing and maintaining one of the most
comprehensive cancer testing menus in the industry.  Our broad test menu enables our sales teams to identify opportunities for increasing revenues from existing clients and
allows us to gain market share from competitors as well as attract new clients looking for a one-stop shop.

Average  revenue  per  test  increased 1.2%,  year-over-year,  reflecting  the  positive  impact  of  our  internal  reimbursement  initiatives,  partially  offset  by  changes  in  Medicare
reimbursement and regulation.

Cost of Revenue and Gross Margin

Average  cost  per  test  decreased 4.5%,  year  over  year, primarily  due  to  increased  automation  in  our  laboratories  as  well  as  the  benefit  of  increased  economies  of  scale. In
addition, our laboratory teams have been extremely focused on reducing their cost per test across all departments.

Cost of revenue includes payroll and payroll-related costs for performing tests, maintenance and depreciation of laboratory equipment, rent for laboratory facilities, laboratory
reagents, probes and supplies, and delivery and courier costs relating to the transportation of specimens to be tested.

Clinical and Pharma Services cost of revenue and gross profit metrics for the periods presented are as follows ($ in thousands):

Cost of revenue:
Clinical Services
Pharma Services

Total Cost of Revenue

Cost of revenue as a % of revenue

Gross Profit:
Clinical Services
Pharma Services

Total Gross Profit
Gross Profit Margin

For the Years Ended December 31,

2018

2017 (as adjusted)

% Change

$

$

$

$

128,297  $
21,179 

149,476  $

54.0 

%

113,576  $
13,689 

127,265  $

46.0 

%

121,785 
16,510 

138,295 
%

57.6 

91,313 
10,643 

101,956 
%

42.4 

5.3  %
28.3 %

8.1  %

24.4 %
28.6 %

24.8 %

For  2018,  consolidated  cost  of  revenue  as  a  percentage  of  revenue  was 54.0%  compared  to 57.6%,  in  2017,  and  2018  gross  profit  margin  was 46.0%  compared  to 42.4%  in
2017. This improvement was partially due to an increase in our revenue per test in 2018 as well as a decrease in our cost per test. This increase was also driven by the divestiture
of Path Logic in the third quarter of 2017.

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NEOGENOMICS, INC.

General and Administrative Expenses

General  and  administrative  expenses  consist  of  employee-related  costs  (salaries,  fringe  benefits,  and  stock  based  compensation  expense)  for  our  billing,  finance,  human
resources,  information  technology  and  other  administrative  personnel.  We  also  allocate  professional  services,  facilities  expense,  IT  infrastructure  costs,  bad  debt  expense,
depreciation, and other administrative-related costs to general and administrative expenses.

Consolidated general and administrative expenses for the periods presented are as follows ($ in thousands):

General and administrative
General and administrative as a % of revenue

$

84,822  $
%

30.7 

70,359  $
%

29.3 

14,463 

20.6 %

For the years ended
December 31.

2018

2017 (as adjusted)

$ Change

% Change

For fiscal 2018, general and administrative expenses increased $14.5 million, compared to 2017, primarily reflecting increases in payroll and payroll related expenses due to
increases  in  headcounts,  depreciation  and  amortization  expense  as  well  as  approximately  $2.5  million  in  moving  expenses  associated  with  the  relocation  of  our  expanded
Houston, Texas laboratory, and $2.3 million in transaction fees and integration expenses associated with the acquisition of Genoptix.

Payroll expense for the year ended December 31, 2018 increased by approximately $8.3 million when compared to the same period in 2017, primarily reflecting additional staff
hired for support functions related to additional growth.  

Depreciation expense for the year ended December 31, 2018 increased by approximately $1.5 million, when compared to the same period in 2017, primarily reflecting increases
in  capital  expenditures  over  the  last  three  years  including  capital  expenditures  associated  with  the  relocation  of  our  expanded  Houston,  Texas  laboratory  and  continued
investment in our laboratory information system.

We  expect  our  general  and  administrative  expenses  to  increase  in  order  to  support  our  anticipated  growth  through  the  addition  of  personnel  and  related  payroll  and  stock
compensation,  increased  expenses  associated  with  the  expansion  and  maintenance  of  our  facilities,  and  continued  investment  in  the  maintenance  and  development  of  our
information  systems.    However,  we  anticipate  that  general  and  administrative  expenses  as  a  percentage  of  consolidated  revenue  will  decrease  over  the  coming  years  as  we
continue to grow.  

Research and Development Expenses

Research and development expenses relate to cost of developing new proprietary and non-proprietary genetic tests, including payroll and payroll-related costs, maintenance of
laboratory equipment, laboratory supplies, outside consultants and experts assisting our research and development team.    

Consolidated research and development expense for the periods presented are as follows ($ in thousands):

Research and development
Research and development as a % of revenue

$

3,001  $

1.1  %

3,636  $

1.5  %

(635)

(17.5)%

For the years ended
December 31.

2018

2017 (as adjusted)

$ Change

% Change

Research  and  development  expenses  for  the  year  ended December  31,  2018  decreased $0.6 million,  when  compared  to  the  same  period  in 2017. This  decrease  was  largely
attributable to reductions in stock based compensation expense, including the impact of our adoption of ASU 2018-07 in the second quarter of 2018.

We anticipate research and development expenditures will increase over time as we continue to invest in innovative projects and bringing new tests to market.

Sales and Marketing Expenses

Sales and marketing expenses are primarily attributable to employee-related costs including sales management, sales representatives, sales and marketing consultants, marketing,
and customer service personnel.  Costs also include various marketing-related costs such as attending trade shows, advertising and maintaining our website.

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Consolidated sales and marketing expenses for the periods presented are as follows ($ in thousands):

Sales and marketing
Sales and marketing as a % of revenue

$

29,402  $
%

10.6 

24,001  $
%

10.0 

5,401 

22.5 %

For the years ended
December 31.

2018

2017 (as adjusted)

$ Change

% Change

Sales and marketing expenses for the year ended December 31, 2018, increased $5.4 million, when compared to the same period in 2017. This increase is primarily attributable
to higher commissions due to our increase in revenues as well as the expansion of our sales team and continued investment in marketing. We expect commissions expense will
increase  over  time  as  the  sales  representatives  continue  to  generate  new  business.  We  expect  our  sales  and  marketing  expenses  over  the  long  term  will  increase  as  our  test
volumes increase.

Net Interest Expense and Other Income

Net interest expense is comprised of interest incurred on our term debt, revolving credit facility and our capital lease obligations, offset by the interest income earned on cash
deposits.  Net interest expense for the year ended December 31, 2018, increased $0.7 million compared to the same period in 2017, reflecting changes in interest rates as well as
the additional $30 million term loan entered into in the second quarter of 2018. We expect our interest expense to fluctuate based on timing of advances and payments on our
revolving credit facility.

Net Income (Loss)

The following table provides the net loss for each period along with the computation of basic and diluted net income per share (in thousands, except per share amounts):

NET INCOME (LOSS) ATTRIBUTABLE TO COMMON STOCKHOLDERS

Basic weighted average common shares outstanding
Effect of potentially dilutive securities

Diluted weighted average shares outstanding

Basic net income (loss) per common share
Diluted net income (loss) per share

Non-GAAP Measures

Use of non-GAAP Financial Measures

Years Ended December 31,

2018

2017 
(as adjusted)

6,088  $

(10,943)

85,618 
5,950 

91,568 

0.07  $
0.07  $

79,426 
— 

79,426 

(0.14)
(0.14)

$

$
$

Our financial results are provided in accordance with accounting principles generally accepted in the United States of America (GAAP) and using certain non-GAAP financial
measures.  Management believes that presentation of operating results using non-GAAP financial measures provides useful supplemental information to investors and facilitates
the analysis of the Company’s operating results and comparison of operating results across reporting periods and between entities. Management also uses non-GAAP financial
measures for financial and operational decision making, planning and forecasting purposes and to manage our business. Management believes that Adjusted EBITDA is a key
metric for our business because it is used by our lenders in the calculation of our debt covenants.  Management also believes that these non-GAAP financial measures enable
investors  to  evaluate  our  operating  results  and  future  prospects  in  the  same  manner  as  management.    The  non-GAAP  financial  measures  do  not  replace  the  presentation  of
GAAP financial results and should only be used as a supplement to, and not as a substitute for, our financial results presented in accordance with GAAP.  There are limitations
inherent in non-GAAP financial measures because they exclude charges and credits that are required to be included in a GAAP presentation, and do not therefore present the
full measure of our recorded costs against its net revenue.  In addition, our definition of the non-GAAP financial measures below may differ from non-GAAP measures used by
other companies.  

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NEOGENOMICS, INC.

Definitions of non-GAAP measures

Non – GAAP EBITDA

We define Non-GAAP “EBITDA” as net income from continuing operations before: (i) interest expense, (ii) tax expense and (iii) depreciation and amortization expense.

Non – GAAP Adjusted EBITDA

We define Non-GAAP “Adjusted EBITDA” as net income from continuing operations before: (i) interest expense, (ii) tax expense, (iii) depreciation and amortization expense,
(iv) non-cash, stock-based compensation and warrant amortization expense, and if applicable in a reporting period (v) transaction expenses related to acquisitions and potential
acquisitions, (vi) non-cash impairments of intangible assets (vii) debt financing costs and (viii) other significant non-recurring or non-operating (income) or expenses.  

Basis for Non-GAAP Adjustments

Our basis for excluding certain expenses from GAAP financial measures, are outlined below:

•

•

•

•

•

Amortization of intangible assets - The intangible assets that give rise to this amortization expense relate to acquisitions, and the amounts allocated to such
intangible  assets  and  the  terms  of  amortization  vary  by  acquisition  and  type  of  asset.  NeoGenomics  excludes  these  items  to  provide  a  consistent  basis  for
comparing operating results across reporting periods, pre- and post-acquisition.

Deemed  dividends  on  preferred  stock -  GAAP  accounting  for  the  unique  structure  of  the  Series A  Redeemable  Convertible  Preferred  Stock  requires  the
Company  to  assume  that  such  preferred  stock  would  be  outstanding  for  its  entire  ten-year  term.  In  addition,  GAAP  requires  that  the  escalating  preferred
dividend rate over time be accelerated for accounting purposes and amortized on a straight-line basis over the ten-year life of the instrument, irrespective of the
minimal  contractual  requirements  for  "paid  in  kind"  stock  dividends  in  the  early  years.  Since  such  implied  dividends  were  not  paid  in  cash,  and  since  the
Company believed that such preferred stock would have been redeemed within the first three years it was outstanding, before any significant dividends accrued
under the contractual terms, the Company believed these non-cash expenses were not meaningful in evaluating the operating performance of the Company and
it would have been misleading to not adjust for such expenses across reporting periods.

Amortization of preferred stock beneficial conversion feature - This non-cash expense is also a direct result of the complex GAAP accounting requirements
for our Series A Redeemable Convertible Preferred Stock. The Company believes this expense is not meaningful in evaluating the operating performance of the
Company, distorts comparisons across reporting periods, and that it would be misleading to not adjust for such expenses across reporting periods.

Loss on sale of business – The impact of disposals of assets or businesses have been excluded as these losses represent infrequent transactions that impact the
comparability between operating periods. We believe the adjustment of these losses supplements the GAAP information by providing a measure that may be
used to assess the sustainability of our operating performance.

Non-cash,  stock-based  compensation  expenses -  Because  many  of  the  company's  full-time  physicians  reside  in  California,  state  regulations  against  the
corporate practice of medicine require us to retain their professional service corporations rather than hire them as employees. Prior to ASU 2018-07, which we
adopted in the second quarter of 2018, GAAP provided that variable stock- based compensation treatment be applied for non-employee service providers. This
variable accounting treatment can cause significant fluctuations in quarterly expense based on changes in the Company's stock price from one quarter to the
next and result in large positive or negative impacts to total operating expenses. Without adjusting for these non-cash expenses, the Company believed it would
have been difficult to compare financial results from core operations across reporting periods on a consistent basis.

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NEOGENOMICS, INC.

•

•

Moving  expenses -  These  expenses  include  costs  associated  with  the  move  of  our  Houston,  Texas  facility  in  2018  and  the  move  of  our  Irvine,  California
facility in 2017 as well as restoring these facilities back to their original condition at the end of the lease terms. We are adjusting for these costs in Adjusted
EBITDA as the moves were related to the Clarient acquisition and will not be annually recurring. Without adjusting for these expenses, the Company believes it
would be difficult to compare financial results from operations across reporting periods on a consistent basis.

Acquisition and integration expenses - We incurred significant expenses in connection with our recent acquisition of Genoptix related to transaction costs
and integration expenses. These expenses include acquisition-related transaction costs, consultants, severance, systems integration and conversion expenses,
and other costs related to integration activities. In order to compare across periods on a consistent basis we believe it is appropriate to exclude these expenses.

We believe that EBITDA and Adjusted EBITDA provide more consistent measures of operating performance between entities and across reporting periods by excluding cash
and non-cash items of expense that can vary significantly between companies.  In addition, Adjusted EBITDA is a metric that is used by our lenders in the calculation of our
debt covenants.  Adjusted EBITDA also assists investors in performing analyses that are consistent with financial models developed by independent research analysts.

EBITDA and Adjusted EBITDA (as defined by us) are not measurements under GAAP and may differ from non-GAAP measures used by other companies.  We believe there
are limitations inherent in non-GAAP financial measures such as EBITDA and Adjusted EBITDA because they exclude a variety of charges and credits that are required to be
included in a GAAP presentation, and do not therefore present the full measure of NeoGenomics recorded costs against its net revenue.  Accordingly, we encourage investors to
consider both non-GAAP results together with GAAP results in analyzing our financial performance.

The  following  is  a  reconciliation  of  GAAP  net  income  (loss)  to  Non-GAAP  EBITDA  and  Adjusted  EBITDA  for  the  years  ending  December  31,  2018  and  2017  ($  in
thousands): 

NET INCOME (LOSS) (per GAAP)

Adjustments to net income (loss):
Interest expense, net
Amortization of intangibles
Income tax expense (benefit)
Depreciation of property and equipment

EBITDA (non-GAAP)

Further Adjustments to EBITDA:

Facility moving expenses and other adjustments
Loss on sale of business
Acquisition and integration related expenses
Non-cash stock-based compensation

ADJUSTED EBITDA (non-GAAP)

Adjusted EBITDA as % of Revenue

49

For the years ended
December 31,

2018

2017 (as adjusted)

$

2,640  $

(396)

6,230 
5,928 
1,184 
15,804 

31,786 

2,486 
— 
2,325 
6,955 

$

43,552  $

15.7 

%

5,540 
6,995 
(2,254)
15,596 

25,481 

620 
1,058 
— 
6,441 

33,600 

14.0 

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NEOGENOMICS, INC.

Results of Operations for the year ended December 31, 2017 as compared with the year ended December 31, 2016

The following table presents the condensed consolidated statements of operations as a percentage of revenue:

NET REVENUE
Cost of revenue

GROSS PROFIT
OPERATING EXPENSES:
General and administrative
Research and development
Sales and marketing
Loss on sale of Path Logic
Impairment charges

Total operating expenses

INCOME FROM OPERATIONS
Interest expense, net

Net loss before income taxes
Income taxes benefit

NET LOSS

Revenue

For the years ended
December 31.

2017 (as adjusted)

2016 (as adjusted)

100.0  %
57.6 %

42.4 %

29.3 %
1.5  %
10.0 %
0.4  %
— %

41.2 %

1.2  %
2.3  %

(1.1)%
(0.9)%

(0.2)%

100.0  %
57.7 %

42.3 %

27.6 %
2.0  %
10.3 %
— %
1.5  %

41.4 %

0.9  %
4.3  %

(3.4)%
(0.7)%

(2.7)%

Clinical and Pharma Services revenue for the periods presented are as follows ($ in thousands):

Net revenues:
Clinical Services
Pharma Services

Total Revenue

2017 (as adjusted)

2016 (as adjusted)

% Change

For the Years Ended December 31,

$

$

213,097  $
27,154 

240,251  $

210,159 
21,649 

231,808 

1.4  %
25.4 %

3.6  %

Consolidated  revenues  increased $8.4  million,  or 3.6%,  year-over-year.    Growth  in  our  Clinical  segment  year-over-year,  was $2.9  million,  or 1.4%.  Testing  volumes  also
increased in our Clinical segment by approximately 16.7% year-over-year.  The increases in revenue and volume were largely due to strong growth in molecular and histology
testing as well as growth in immunohistochemistry tests due to demand for the PD-L1 test as a result of the FDA approving Pembrolizumab (Keytruda) in October 2016 as first-
line treatment for PD-L1 positive non-small cell lung cancer.  We also noted accelerated growth in flow cytometry and FISH during the second half of the year. While revenues
increased year over year, we believe the impact of Hurricanes Harvey and Irma depressed our revenues by approximately $1.0 million in the third quarter of 2017.

Pharma Services revenue increased approximately $5.5 million, or 25.4%, year-over-year. In addition, our backlog of signed contracts grew from $28.3 million as of December
31, 2016 to $68.7 million as of December 31, 2017.

The following table shows clinical genetic testing revenue, cost of revenue, requisitions received and tests performed for the years ended December 31, 2017 and 2016.  This
data excludes tests performed for Pharma Services and tests performed by Path Logic.  Testing revenue and cost of revenue are presented in thousands below:

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Requisitions received (cases)
Number of tests performed
Average number of tests/requisition

Total clinical genetic testing revenue
Average revenue/requisition
Average revenue/test

Cost of revenue
Average cost/requisition
Average cost/test

2017 (as adjusted)

2016 (as adjusted)

% Change

December 31,

394,520 
657,394 
1.67 

209,584  $
531  $
319  $

117,838  $
299  $
179  $

361,220 
563,132 
1.56 

203,213 
563 
361 

113,373 
314 
201 

$
$
$

$
$
$

9.2  %
16.7 %
7.1  %

3.1  %
(5.6)%
(11.6)%

3.9  %
(4.7)%
(11.1)%

We continued to realize growth in clinical revenue, which we believe is the direct result of our efforts to innovate by developing and maintaining one of the most comprehensive
cancer testing menus in the industry. Our broad test menu enables our sales teams to identify opportunities for increasing revenues from existing clients and allows us to gain
market  share  from  competitors.  New  molecular  and  immunohistochemistry  tests  such  as  Microsatellite  Instability,  DNA  Mismatch  Repair  (MMR),  PD1  and  PD-L1  have
continued to show solid growth and have increased our volume and revenue growth. We believe the field of immunotherapy will continue to show substantial growth in coming
years and our ability to offer multi-modality testing in one laboratory will allow us to capitalize on this increased demand.

Average revenue per test decreased year-over-year, primarily due to the change in test mix, specifically the increase in PD-L1 testing which  has  a  lower  average  unit  price
(“AUP”)  than  our  overall  Company AUP.  Additionally, revenue per test decreased as a result of the 2017 Medicare Physician Fee Schedule, which reduced Medicare Flow
Cytometry reimbursement by 19%, and the combination of Clarient and NeoGenomics insurance contracts as several contracts were amended or renegotiated during 2017.

PathLogic was sold on August 1, 2017 as has been excluded from the above table for comparative purposes. During the seven months of ownership in 2017 NeoGenomics
recorded revenue from PathLogic of $3.5 million. During twelve months of ownership in 2016, NeoGenomics recorded revenue from PathLogic of $6.9 million.

Cost of Revenue and Gross Margin

The decreases to our average revenue per test were offset by our higher volumes and 11.1% reduction in cost per test. The cost per test reductions were partially a result of the
change in test mix, specifically the higher mix of lower cost histology tests. In addition, we continue to have success in reducing costs in the laboratory as synergies are being
realized from the consolidation of our Irvine and Aliso Viejo, California laboratories. Our laboratory teams also made significant progress during 2017 lowering our supplies
costs and improving the efficiency of our medical technologists. We have also seen a reduction in send-out costs, as it is unlikely that we would need to send a test to another
laboratory, due to our extensive test menu.

Cost of revenue includes payroll and payroll-related costs for performing tests, depreciation of laboratory equipment, rent for laboratory facilities, laboratory reagents, probes
and supplies, and delivery and courier costs relating to the transportation of specimens to be tested. Clinical and Pharma Services cost of revenue and gross profit metrics for the
periods presented are as follows ($ in thousands):

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For the Years Ended December 31,

2017 (as adjusted)

2016 (as adjusted)

% Change

Cost of revenue:
Clinical Services
Pharma Services

Total Cost of Revenue

Cost of revenue as a % of revenue

Gross Profit:
Clinical Services
Pharma Services

Total Gross Profit
Gross Profit Margin

General and Administrative Expenses

$

$

$

$

121,785  $
16,510 

138,295  $

57.6 

%

91,313  $
10,643 

101,956  $

120,437 
13,267 

133,704 
%

57.7 

89,722 
8,382 

98,104 
%

1.1  %
24.4 %

3.4  %

1.8  %
27.0 %

3.9  %

42.4 

%

42.3 

General and administrative expenses relate to billing, bad debts, finance, human resources, information technology and other administrative functions. They primarily consist of
employee related costs (such as salaries, fringe benefits, and stock-based compensation expense), professional services, facilities expense, and depreciation and administrative-
related costs allocated to general and administrative expenses.

Consolidated general and administrative expenses for the periods presented are as follows ($ in thousands):

For the years ended
December 31.

2017 (as adjusted)

2016 (as adjusted)

$ Change

% Change

General and administrative
General and administrative as a % of revenue

$

70,359  $
%

29.3 

63,926  $
%

27.6 

6,433 

10.1 %

For fiscal 2017, general and administrative expenses increased $6.4 million, compared to 2016, primarily reflecting increases in bad debt, professional fees, and personnel fees
including stock based compensation, and depreciation and amortization expense.

Professional  fees  for  the  year  ended December 31, 2017  increased  by  approximately $2.4 million,  when  compared  to  the  same  period  in 2016,  primarily  due  to  fees  in  2017
related to the Pharma Services facility in Rolle, Switzerland, and an increase in legal accruals related to a lawsuit brought against Clarient.

Depreciation and amortization expenses for the year ended December 31, 2017 increased by approximately $1.9 million, when compared to the same period in 2016, primarily
reflecting increases in capital expenditures over the last two years.

Payroll expenses for the year ended December 31, 2017 increased by approximately $1.5 million when compared to the same period in 2016, primarily reflecting additional staff
hired for certain functions such as billing, IT and accounts payable.

Research and Development Expenses

Consolidated research and development expenses for the periods presented are as follows ($ in thousands):

Research and development
Research and development as a % of revenue

$

3,636  $

1.5  %

4,649  $

2.0  %

(1,013)

(21.8)%

For the years ended
December 31.

2017 (as adjusted)

2016 (as adjusted)

$ Change

% Change

Research and development expenses for the year ended December 31, 2017 decreased $1.0 million, when compared to the same period in 2016, primarily reflecting a decrease in
contract labor and amortization expense, partially offset by an increase in payroll and payroll-related costs. The decrease in amortization expense reflected Health Discovery
Corporation license agreements, which were being amortized as intangible assets in 2016 but were fully impaired in the fourth quarter of 2016.

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Sales and Marketing

Consolidated sales and marketing expenses for the periods presented are as follows ($ in thousands):

Sales and marketing
Sales and marketing as a % of revenue

$

24,001  $
%

10.0 

23,910  $
%

10.3 

91 

0.4  %

2017 (as adjusted)

2016 (as adjusted)

$ Change

% Change

For the years ended
December 31.

For 2017, sales and marketing expenses as a percentage of revenue improved by 32 basis points compared to 2016, primarily reflecting leverage of our sales team on increased
volumes and revenue in 2017. The $0.1 million increase in sales and marketing expenses primarily reflects higher commissions in line with increased revenue. In addition, we
increased our investment in marketing-related activities in 2017, including trade shows and online marketing.

Net interest Expense and Other Income

Net interest expense is comprised of interest incurred on our Term Loan Facility, Revolving Facility and our capital lease obligations, offset by the interest income we earn on
cash  deposits. Net  interest  expense  decreased $4.5 million for the year ended December 31, 2017  compared  to  the  same  period  in 2016,  primarily  reflecting  the  significantly
lower borrowing rate on the Credit Agreement entered into in December of 2016.  In addition, we entered into a swap agreement to hedge a significant portion of the interest on
our term loan; however, part of that loan is not hedged, nor is our Revolving Facility and they will continue to fluctuate as the LIBOR rates change.

Net Loss

The following table provides the net loss for each period along with the computation of basic and diluted net loss per share for the year ended December 31, 2017 and 2016 (in
thousands, except per share amounts):

NET  LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS

Basic weighted average common shares outstanding
Effect of potentially dilutive securities

Diluted weighted average shares outstanding

Basic net loss per common share
Diluted net loss per common share

For the years ended December 31,

2017 (as adjusted)

2016 (as adjusted)

(10,943) $

(30,816)

79,426 
— 

79,426 

(0.14) $
(0.14) $

77,542 
— 

77,542 

(0.40)
(0.40)

$

$
$

The following is a reconciliation of GAAP net loss to Non-GAAP EBITDA and Adjusted EBITDA for the years ending December 31, 2017 and 2016 ($ in thousands): 

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NET LOSS (GAAP)
Adjustments to Net Loss:

Interest expense, net
Amortization of intangibles
Income taxes (benefit)
Depreciation of property and equipment

EBITDA (non-GAAP)

Further Adjustments to EBITDA:

Facility moving expenses and other adjustments
Loss on sale of business
Non-cash stock-based compensation

ADJUSTED EBITDA (non-GAAP)

Adjusted EBITDA as a % of revenue

Liquidity and Capital Resources 

For the years ended December 31,

2017 (as adjusted)

2016 (as adjusted)

(396) $

5,540 
6,995 
(2,254)
15,596 

25,481 

620 
1,058 
6,441 

33,600  $

14.0 

%

(6,142)

9,998 
7,272 
(1,701)
15,937 

25,364 

3,471 
— 
5,438 

34,273 

14.8 

%

$

$

The following table presents a summary of our cash flows provided by (used in) operating, investing and financing activities for the years ended December 31, 2018, 2017 and
2016 as well as the period ending cash and cash equivalents and working capital (in thousands).

Net cash provided by (used in):

Operating activities

Investing activities
Financing activities
Effects of foreign exchange rate changes on cash and cash equivalents

Net increase (decrease) in cash and cash equivalents
Cash and cash equivalents, beginning of period

Cash and cash equivalents, end of period

Working Capital (1), end of period

(1) Defined as current assets less current liabilities.

Cash Flows from Operating Activities

For the years ended December 31,

2018

2017 
(as adjusted)

2016 
(as adjusted)

$

$

$

44,786  $

(139,687)
91,959 
(68)

(3,010)
12,821 

9,811  $

42,743  $

18,037  $
(13,690)
(4,095)
44 

296 
12,525 

12,821  $

49,404  $

21,477 
(6,501)
(25,871)
— 

(10,895)
23,420 

12,525 

39,609 

During the year ended December 31, 2018, cash flows from operating activities were $44.8 million, a $26.7 million increase compared to 2017. The increase was primarily due
to an increase and accounts payable and other accrued expenses of $12.9 million. Our increase in accounts payable and accrued expenses primarily reflects higher payroll and
payroll-related expenses and increased accrued expenses associated with higher test volumes and strategic initiatives. The change in cash flows from operations is also due to
our net income for the period ending December 31, 2018 compared to our net loss for the period ended December 31, 2017.

During the year ended December 31, 2017, cash flows from operating activities were $18.0 million, a $3.4 million  decrease  compared  to 2016.  The decrease primarily reflects
an increase in working capital of $9.8 million. The increase in working capital primarily reflects an increase in our accounts receivable and a decrease in accounts payable,
partially offset by increases in accrued expenses. The change in cash flows from operations is also due to lower net loss for the period ending December 31, 2017 compared to
our net loss for 2016.

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Cash Flows from Investing Activities

During  the  year  ended December  31,  2018,  cash  used  in  investing  activities  increased  by $126.0 million  compared  to  the  same  period  in 2017.  This  increase  was  primarily
related to the cash consideration of approximately $125.4 million related to the acquisition of Genoptix in December of 2018.

During the year ended December 31, 2017, cash used in investing activities increased by $7.2 million compared to the same period in 2016. This increase was due to equipment
purchases and building improvements, which were necessary to support our continued growth and efficiency. Specifically, we remodeled and upgraded our laboratory facilities
in Aliso Viejo, California, expanded our Houston, Texas facility, opened our Rolle, Switzerland laboratory, invested in additional laboratory equipment to accommodate our
growth and updated existing equipment that was acquired with the purchase of Clarient. These investments were made to help increase our capacity to handle future growth. We
also invested in a new trade show booth as well as upgrades to our IT security environment and our next generation Laboratory Information System (LIS).

Cash Flows from Financing Activities

During  the  year  ended December 31, 2018, cash flows provided by financing activities increased by approximately $96.1 million compared to the same period in 2017.  Cash
provided by financing activities at December 31, 2018 consisted primarily of net cash proceeds of $135.1 million from the equity offering completed in August 2018, partially
offset by $50.1 million paid to redeem 6.9 million shares of Series A Redeemable Convertible Preferred Stock in June 2018.  Cash flows from financing activities also included
an increase in the term loan of $30.0 million, which was partially offset by a $20.4 million repayment on the Revolving Facility.

During  the  year  ended December 31, 2017, cash flows from financing activities decreased by approximately $21.8 million  compared  to  the  same  period  in 2016.  Cash  flows
from financing activities for 2017 included $5.0 million in advances on our revolving credit facility, partially offset by a $2.5 million repayment on our revolving credit facility
as well as a $3.8 million in repayment on our term loan. In 2016, $55.0 million was paid to redeem a portion of our Series A Redeemable Convertible Preferred Stock offset by
$20.0 million and $12.9 million in proceeds received on our Term Loan and Revolving Credit Facilities, respectively. The 2016 revolving credit facility was originally used to
finance the acquisition of Clarient.

Credit Facility

We entered into a Credit Agreement in December 2016, which was subsequently amended in June 2018 to include additional loan capacity.  In order to reduce our exposure to
interest rate fluctuations on this floating rate debt obligation, we entered into interest rate swap agreements. For more information on these hedging instruments, see Note H to
Consolidated  Financial  Statements  herein. The  interest  rate  swap  agreement  effectively  converts  a  portion  of  our  floating  rate  debt  to  a  fixed  obligation,  thus  reducing  the
impact of interest rate changes on future interest expense. We believe this strategy will enhance our ability to manage cash flow within our Company.

Liquidity Outlook

We had approximately $9.8 million in cash and cash equivalents as of December 31, 2018.  In addition, we have a Revolving Facility which provides for up to $75 million in
borrowing capacity of which $5 million is outstanding at December 31, 2018. Based on our level of Adjusted EBITDA and the balance drawn, approximately $60.9 million was
available.  We believe that the cash on hand, available credit lines and positive cash flows generated from operations will provide adequate resources to meet our operating
commitments and interest payments for at least the next 12 months from the issuance of these financial statements.  

Related Party Transactions

See Note N to our consolidated financial statements for a description of our related party transactions.

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Contractual Obligations

The following table summarizes our significant contractual obligations as of December 31, 2018 ($ in thousands):

Purchase obligations
Capital lease obligations
Operating lease obligations

Principal payments on long term debt (1)
Interest on swap agreement (2)
Interest on Term Loan Facility (3)
Interest on Revolving Facility (4)
Total contractual obligations

Total

2019

2020 to 2021

2022 to 2023

After 2023

$

$

550  $

220  $

330  $

12,150 
9,671 
101,750 
5,563 
13,622 
814 

6,706 
5,247 
7,873 
1,391 
5,063 
286 

5,444 
3,880 
93,877 
4,172 
8,559 
528 

144,120  $

26,786  $

116,790  $

—  $
— 
544 
— 
— 
— 
— 

544  $

— 
— 
— 
— 
— 
— 
— 

— 

1.

2.
3.

4.

Amounts represent required principal debt payments on our Term Loan Facility and Revolving Facility.  For a full description of the terms of our indebtedness and the
related debt service requirements, see Note G.
Amounts represent fixed interest owed on the swap agreement. For further details of the swap agreement, see Note H.
Amounts represent interest payments due on the Term Loan Facility assuming principal payments are made as specified in the loan agreement and estimated interest
rates based on the rates in effect at December 31, 2018.
Amounts represent interest payments due on the Revolving Facility based on the December 31, 2018 principal balance and estimated interest rates based on the interest
rates in effect at December 31, 2018.

Capital Expenditures
We currently forecast capital expenditures in order to execute on our business plan and maintain growth; however, the actual amount and timing of such capital expenditures
will ultimately be determined by the volume of business. We currently anticipate that our capital expenditures for the year ended December 31, 2019 will be in the range of $16
million  to  $20  million.  We  have  funded  and  plan  to  continue  funding  these  capital  expenditures  with  capital  lease  financing  arrangements,  cash,  and  through  bank  loan
facilities, if necessary.

Recently Adopted and Issued Accounting Guidance

Adopted
In June 2018, the FASB issued ASU 2018-07, Compensation - Stock Compensation. This standard expands the scope of current stock compensation recognition standards to
include share-based payment transactions for acquiring goods and services from nonemployees. ASU 2018-07 is effective for fiscal years beginning after December 15, 2018,
including  interim  periods  within  that  fiscal  year,  with  early  adoption  permitted.  The  Company  early  adopted  this  ASU  on  April  1,  2018.  The  adoption  of  this  standard
substantially aligned the accounting for share based payments to employees and nonemployees. Under the new standard, the Company recorded a cumulative adjustment of
$1.1 million to increase retained earnings and decrease APIC.

In August  2017,  the  FASB  issued ASU  2017-12, Derivatives  and  Hedging. This standard refines hedge accounting to better align an entity’s risk management activities and
financial reporting for hedging relationships through changes to both the designation and measurement guidance for qualifying hedging relationships and the presentation of
hedge  results.  The  amended  guidance  also  expands  items  eligible  for  hedge  accounting  and  simplifies  the  hedge  effectiveness  testing. ASU  2017-12  is  effective  for  annual
periods beginning after December 15, 2018 and interim periods within those annual periods. Early adoption is permitted. The Company early adopted this standard on April 1,
2018 and applied this guidance to the cash flow hedge entered into in June 2018. See Note H. The adoption of ASU 2017-12 did not have a material effect on its consolidated
financial statements.

In May 2014, the FASB issued ASU 2014-09, which amends FASB Accounting Standards Codification by creating Topic 606, Revenues from Contracts with Customers.  This
standard  update  calls  for  a  number  of  revisions  in  the  revenue  recognition  rules.  The  Company  adopted  this ASU  on  January  1,  2018  using  a  full  retrospective  method  of
adoption. Under this method, the Company has restated its results for each prior reporting period presented as if ASC 606 had been effective for those periods.

The adoption of this standard required us to implement new revenue policies, procedures and internal controls related to revenue recognition. In addition, the adoption resulted
in enhanced financial statement disclosures surrounding the nature, amount, timing and uncertainty of revenue and cash flows arising from contracts with customers. For further
details, see Note C.

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The new standard impacts each of our two reportable segments differently due to the transactional nature of the Clinical Services segment versus the generally long-term nature
of our Pharma Services contracts. The specific effect on our reportable segments is explained below:

Clinical Services Revenue

Under the new standard, substantially all of our bad debt expense, which has historically been presented as part of general and administrative expense, is considered an implicit
price concession and is reported as a reduction in revenue. As a result of ASC 606, we reported a material cumulative reduction in clinical revenue from previously reported
periods and a similar reduction in general and administrative expenses.

Pharma Services Revenue

The adoption of ASC 606 also resulted in changes to the timing of revenue recognition related to Pharma Services contracts as certain individual deliverables such as study
setup fees, for which revenue was previously recognized in the period when the deliverables were completed and invoiced, will be recognized over the remaining performance
period under the new standard. Additionally, certain costs to obtain contracts, primarily for sales commissions, are capitalized when incurred and are amortized over the term of
the contract. Under ASC 606, the Company is required to make estimates of the total transaction price per contract, including estimates of variable consideration and the number
of performance obligations, and recognize the estimated amount as revenue as it transfers control of the product or performance obligations to its customers. The estimation of
total  transaction  price,  number  of  performance  obligations,  variable  consideration  and  the  application  of  the  related  constraint,  was  not  required  under  previous  GAAP  and
requires the use of significant management judgment and estimates. The Company elected certain practical expedients as allowed under the standard including the following:
contracts that began and ended within the same annual reporting period were not restated; contracts with variable consideration were estimated using the transaction price at the
date the contract was completed; contract modifications that occurred prior to the earliest reporting period have not been retrospectively restated but have rather been reflected
as an aggregate adjustment in the earliest reporting period. The cumulative effect of this standard did not result in a material change to our Pharma Services revenue.

 ASC 606 Adoption Impact to Previously Reported Results

We adjusted our condensed consolidated financial statements from amounts previously reported due to the adoption of ASC 606.

Select condensed consolidated balance sheet line items, which reflect the adoption of ASC 606, are as follows (in thousands):

As Reported

Impact of Adoption

As Adjusted

12/31/2017

Prepaids and other current assets

Other assets
Total Assets

Pharma contract liability
Long-term pharma contract liability
Deferred income tax liability, net
Stockholders' Equity
Total Liabilities and Stockholders' Equity

$

$

$

$

$

$

$

4,241 
689 

343,340 

— 
— 
6,307 
172,918 

343,340 

$

57

912 
202 

1,114 

1,406 
283 
381 
(956)

1,114 

$

$

$

$

5,153 
891 

344,454 

1,406 
283
6,688 
171,962 

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NEOGENOMICS, INC.

Select condensed consolidated statement of operations line items, which reflect the adoption of ASC 606, are as follows (in thousands):

For the Twelve Months Ended December 31, 2017

As Reported

Impact of Adoption

As Adjusted

Net Revenue
Clinical Services
Pharma Services
Total Revenue

Gross Margin

Total operating expenses 
Income from Operations
Interest expense
Other expense
Income tax (benefit)
Net Loss

Net Revenue
Clinical Services
Pharma Services

Total Revenue
Gross Profit (Loss)

Total operating expenses 
Income from Operations
Interest expense
Other expense
Income tax (benefit) expense

Net Income (Loss)

$

$

$

$

$

231,748 
26,863 

258,611 
120,316 

117,992 
2,324 
5,540 
265 
(2,635)

$

(18,651)
291 

(18,360)
(18,360)

(18,938)
578 
— 
(253)
381 

(846)

$

450 

$

As Reported

Impact of Adoption

As Adjusted

For the Twelve Months Ended December 31, 2016

222,015 
22,068 

244,083 
110,379 

107,805 
2,574 
9,998 
— 
(1,701)

(5,723)

$

$

$

(11,856) $
(419)

(12,275)
(12,275)

(11,856)
(419)
— 
— 
— 

(419)

213,097 
27,154 

240,251 
101,956 

99,054 
2,902 
5,540 
12 
(2,254)

(396)

210,159 
21,649 

231,808 
98,104 

95,949 
2,155 
9,998 
— 
(1,701)

(6,142)

In  May  2017,  the  FASB  issued  ASU  2017-09, Compensation  –  Stock  Compensation.  This  standard  provides  guidance  related  to  the  scope  of  stock  option  modification
accounting, to reduce diversity in practice and reduce cost and complexity regarding existing guidance. This update is effective for annual periods beginning after December 15,
2017. The Company adopted this standard on January 1, 2018. The adoption of this standard did not have an impact on the consolidated financial statements.

In January 2017, the FASB issued ASU No. 2017-04, Intangibles – Goodwill and Other: Simplifying the Test for Goodwill Impairment. This standard eliminates Step 2 of the
goodwill  impairment  test.  Instead,  an  entity  should  perform  its  annual  or  interim  goodwill  impairment  test  by  comparing  the  fair  value  of  a  reporting  unit  with  its  carrying
amount. An entity should recognize an impairment charge for the amount by which the carrying amount exceeds the reporting unit’s fair value; however, the loss recognized
should not exceed the total amount of goodwill allocated to that reporting unit. This update is effective for annual and interim periods beginning after December 15, 2019. The
Company early adopted this standard on January 1, 2018. The adoption of this standard did not have an impact on the consolidated financial statements.

In August 2016, the FASB issued ASU 2016-15, Statement of Cash Flows – Classification of Certain Cash Receipts and Cash Payments. This standard clarifies how specific
cash receipts and cash payments are classified and presented in the statement of cash flows. This update is effective for fiscal years and interim periods within those fiscal years
beginning after December 15,

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2017. The Company adopted this standard on January 1, 2018. The adoption of this standard did not have an impact on the consolidated financial statements.

In February 2016, the FASB issued ASU 2016-02, Leases. This standard was issued to increase transparency and comparability among organizations by recognizing lease assets
and lease liabilities, including for operating leases, on the balance sheet and disclosing key information about leasing arrangements. This update is effective for fiscal years, and
interim periods within those fiscal years, beginning after December 15, 2018. We adopted this standard on January 1, 2019 using a modified transition approach under which a
cumulative-effect adjustment to retained earnings will be recognized on the date of adoption.

The Company has implemented an information system and changed business processes in order to accumulate the appropriate data and calculate and record right-of-use assets,
lease liabilities and the related expense. We do not currently expect that the adoption will have a material impact on our results of operations; however, based on our portfolio of
operating  leases,  we  expect  to  recognize  approximately  $8  -  $10  million  of  right-of-use  assets  and  corresponding  lease  liabilities  on  our  consolidated  balance  sheet  upon
adoption.

Off Balance Sheet Arrangements

We do not use special purpose entities or other off-balance sheet financing techniques that we believe have, or are reasonably likely to have, a current or future material effect
on our financial condition, changes in financial condition, revenues or expenses, results of operations, liquidity or capital resources.

Effects of Inflation

We do not believe that inflation has had a material impact on our business, revenues, or operating results during the periods presented.

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ITEM 7A. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

Market risk is the potential loss arising from adverse changes in market rates and prices, such as foreign currency exchange rates, interest rates and other relevant market rate or
price changes. We are exposed to market risks, including changes in interest rates and changes in foreign currency exchange rates.  

Interest Rate Risk

The Company is exposed to market risk associated with changes in the LIBOR interest rate.  The Company regularly evaluates its exposure to such changes and may elect to
minimize this risk through the use of interest rate swap agreements.  During the fourth quarter of 2016, the Company entered into a Credit Agreement which provides for a
$75.0 million Term Loan Facility as well as a $75.0 million Revolving Credit Facility. During the second quarter of 2018, the Credit Agreement was amended providing for an
additional term loan of $30.0 million. Borrowings under these facilities bear interest at a variable rate based on one-month LIBOR plus a margin. In December of 2016 and June
of 2018, the Company entered into interest rate swap agreements to reduce our exposure to interest rate fluctuations on our variable rate debt obligations. These agreements
have a notional amount of $50.0 million and $20.0 million, respectively.  As of December 31, 2018, the Company had approximately $31.8 million of unhedged variable rate
debt under the senior secured credit facility. For further details regarding our significant accounting policies relating to derivative instruments and hedging activities, see Note B
to our Consolidated Financial Statements included in this Annual Report.  

Each quarter-point increase or decrease in the one-month LIBOR rate would result in a change in the Company's interest expense by approximately $0.1 million per year based
on the unhedged debt outstanding at December 31, 2018.

Foreign Currency Exchange Risk

We  have  expanded  our  business  into  Europe  and  in  2018  further  expanded  by  opening  a  laboratory  in  Singapore. Our  international  revenues  and  expenses  denominated  in
foreign currencies (primarily Swiss Francs), expose us to the risk of fluctuations in foreign currency exchange rates against the U.S. dollar.  We do not  hedge foreign currency
exchange risks and do not currently feel that these risks are significant.

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ITEM 8. FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

INDEX TO CONSOLIDATED FINANCIAL STATEMENTS

Report of Independent Registered Public Accounting Firm – Crowe LLP
Consolidated Balance Sheets as of December 31, 2018 and 2017
Consolidated Statements of Operations for the years ended December 31, 2018, 2017 and 2016.
Consolidated Statements of Comprehensive Loss for the years ended December 31, 2018, 2017 and 2016
Consolidated Statements of Redeemable Convertible Preferred Stock and Stockholders’ Equity for the years ended December 31, 2018, 2017 and 2016.
Consolidated Statements of Cash Flows for the years ended December 31, 2018, 2017 and 2016.
Notes to Consolidated Financial Statements.

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NEOGENOMICS, INC.

Report of Independent Registered Public Accounting Firm

Shareholders and the Board of Directors of NeoGenomics, Inc.
Fort Myers, Florida

Opinions on the Financial Statements and Internal Control over Financial Reporting

We have audited the accompanying consolidated balance sheets of NeoGenomics, Inc. (the “Company”) as of December 31, 2018 and 2017, the related consolidated statements
of operations, comprehensive income (loss), redeemable convertible preferred stock and stockholders’ equity, and cash flows for each of the years in the three-year period ended
December 31, 2018, and the related notes (collectively referred to as the “financial statements”). We also have audited the Company’s internal control over financial reporting
as  of  December  31,  2018,  based  on  criteria  established  in  Internal  Control  –  Integrated  Framework:  (2013)  issued  by  the  Committee  of  Sponsoring  Organizations  of  the
Treadway Commission (COSO).

In our opinion, the financial statements referred to above present fairly, in all material respects, the financial position of the Company as of December 31, 2018 and 2017, and
the  results  of  its  operations  and  its  cash  flows  for  each  of  the  years  in  the  three-year  period  ended  December  31,  2018  in  conformity  with  accounting  principles  generally
accepted  in  the  United  States  of America. Also  in  our  opinion,  the  Company  maintained,  in  all  material  respects,  effective  internal  control  over  financial  reporting  as  of
December 31, 2018, based on criteria established in Internal Control – Integrated Framework: (2013) issued by COSO.

Basis for Opinions

The  Company’s  management  is  responsible  for  these  financial  statements,  for  maintaining  effective  internal  control  over  financial  reporting,  and  for  its  assessment  of  the
effectiveness  of  internal  control  over  financial  reporting,  included  in  the  accompanying  “Management’s  Report  on  Internal  Control  Over  Financial  Reporting.”  Our
responsibility is to express an opinion on the Company’s financial statements and an opinion on the Company’s internal control over financial reporting based on our audits.  We
are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (“PCAOB”) and are required to be independent with respect to
the Company in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audits to obtain reasonable assurance about
whether the financial statements are free of material misstatement, whether due to error or fraud, and whether effective internal control over financial reporting was maintained
in all material respects.

Our audits of the financial statements included performing procedures to assess the risks of material misstatement of the financial statements, whether due to error or fraud, and
performing  procedures  that  respond  to  those  risks.  Such  procedures  included  examining,  on  a  test  basis,  evidence  regarding  the  amounts  and  disclosures  in  the  financial
statements. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of
the financial statements. Our audit of internal control over financial reporting included obtaining an understanding of internal control over financial reporting, assessing the risk
that a material weakness exists, and testing and evaluating the design and operating effectiveness of internal control based on the assessed risk. As permitted, the Company has
excluded the operations of Genesis Acquisition Holdings Corp., acquired during 2018, which is described in Note E of the consolidated financial statements, from the scope of
management’s report on internal control over financial reporting. As such, it has also been excluded from the scope of our audit of internal control over financial reporting. Our
audits also included performing such other procedures as we considered necessary in the circumstances. We believe that our audits provide a reasonable basis for our opinions.

Definition and Limitations of Internal Control Over Financial Reporting

A company’s internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of
financial statements for external purposes in accordance  with  generally  accepted  accounting  principles. A company’s internal control over financial reporting includes those
policies and procedures that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the assets of the
company;  (2)  provide  reasonable  assurance  that  transactions  are  recorded  as  necessary  to  permit  preparation  of  financial  statements  in  accordance  with  generally  accepted
accounting principles, and that receipts and expenditures of the company are being made only in accordance with authorizations of management and directors of the company;
and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company’s assets that could have a material
effect on the financial statements.

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Because  of  its  inherent  limitations,  internal  control  over  financial  reporting  may  not  prevent  or  detect  misstatements. Also,  projections  of  any  evaluation  of  effectiveness  to
future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures
may deteriorate.

We have served as the Company's auditor since 2014.

Indianapolis, Indiana
February 26, 2019

Crowe LLP

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NEOGENOMICS, INC.

CONSOLIDATED BALANCE SHEETS
(In thousands, except share amounts)

As of December 31,

2018

2017 
(as adjusted)

ASSETS
Current assets

Cash and cash equivalents
Accounts receivable
Inventories
Prepaid assets
Other current assets

Total current assets

Property and equipment (net of accumulated depreciation of $50,127 and $40,530,
respectively)
Intangible assets, net
Goodwill
Other assets

Total assets

LIABILITIES, REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ EQUITY
Current liabilities

Accounts payable
Accrued compensation
Accrued expenses and other liabilities
Short-term portion of car loans
Short-term portion of capital leases
Short-term portion of term loan
Pharma contract liability

Total current liabilities

Long-term liabilities

Long-term portion of car loans
Long-term portion of capital leases
Long-term portion of term loan, net
Revolving credit facility, net
Other long-term liabilities
Deferred income tax liability, net

Total long-term liabilities

Total liabilities

Commitments and contingencies - see Note M
Redeemable convertible preferred stock:

$

$

$

9,811  $
76,919 
8,650 
7,727 
561 

103,668 

60,888 
140,029 
197,892 
2,538 

505,015  $

17,779  $
19,062 
8,986 
— 
6,298 
7,873 
927 

60,925 

— 
5,250 
87,880 
5,000 
3,060 
22,457 

123,647 

184,572 

12,821 
60,427 
7,474 
4,152 
1,001 

85,875 

36,504 
74,165 
147,019 
891 

344,454 

10,450 
9,482 
6,144 
49 
5,190 
3,750 
1,406 

36,471 

20 
5,283 
66,616 
24,516 
283 
6,688 

103,406 

139,877 

Series A Redeemable Convertible Preferred Stock, $0.001 par value, (50,000,000 shares authorized; and 0 and 6,864,000
shares issued and outstanding, respectively)

— 

32,615 

Stockholders' equity

Common stock, $0.001 par value, (250,000,000 shares authorized; 94,465,440 and 80,462,574 shares issued and
outstanding, respectively)
Additional paid-in capital
Accumulated other comprehensive income
Accumulated deficit

Total stockholders’ equity

94 
372,186 
(579)
(51,258)

320,443 

Total liabilities, redeemable convertible preferred stock and stockholders' equity

$

505,015  $

80 
230,030 
274 
(58,422)

171,962 

344,454 

See notes to consolidated financial statements.

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NEOGENOMICS, INC.

CONSOLIDATED STATEMENTS OF OPERATIONS
(In thousands, except per share amounts)

NET REVENUE

Clinical Services
Pharma Services

Total Revenue

Cost of revenue

GROSS MARGIN
Operating expenses:

General and administrative
Research and development
Sales and marketing
Loss on sale of Path Logic
Impairment charges

Total operating expenses
INCOME FROM OPERATIONS

Interest expense and debt termination fees, net
Other expense (income)

Income (loss) before taxes
Income tax expense (benefit)

NET INCOME (LOSS)

Deemed dividends on preferred stock
Amortization of preferred stock beneficial conversion feature
Gain on redemption of preferred stock

NET INCOME (LOSS) ATTRIBUTABLE TO COMMON STOCKHOLDERS

NET INCOME (LOSS) PER SHARE ATTRIBUTABLE TO COMMON STOCKHOLDERS

Basic
Diluted

WEIGHTED AVERAGE COMMON SHARES OUTSTANDING:

Basic
Diluted

$

$

$
$

For the years ended December 31,

2018

2017 
(as adjusted)

2016 
(as adjusted)

241,873  $
34,868 

276,741 

149,476 

127,265 

84,822 
3,001 
29,402 
— 
— 

117,225 
10,040 
6,230 
(14)

3,824 
1,184 

2,640 
10,198 
(4,571)
(9,075)

213,097  $
27,154 

240,251 

138,295 

101,956 

70,359 
3,636 
24,001 
1,058 
— 

99,054 
2,902 
5,540 
12 

(2,650)
(2,254)

(396)
3,645 
6,902 
— 

210,159 
21,649 

231,808 

133,704 

98,104 

63,926 
4,649 
23,910 
— 
3,464 

95,949 
2,155 
9,998 
— 

(7,843)
(1,701)

(6,142)
18,011 
6,663 
— 

6,088  $

(10,943) $

(30,816)

0.07  $
0.07  $

(0.14) $
(0.14) $

85,618 
91,568 

79,426 
79,426 

(0.40)
(0.40)

77,542 
77,542 

See notes to consolidated financial statements.

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CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS)
(In thousands)

NET INCOME (LOSS)

OTHER COMPREHENSIVE INCOME (LOSS), NET OF TAX:

Foreign currency translation adjustments
Gain (loss) on effective cash flow hedge

Total other comprehensive income (loss), net of tax

COMPREHENSIVE INCOME (LOSS)

For the years ended December 31,

2018

2017
(as adjusted)

2016 
(as adjusted)

2,640  $

(396) $

(6,142)

(68)
(785)

(853)

44 
230 

274 

— 
— 

— 

1,787  $

(122) $

(6,142)

$

$

See notes to consolidated financial statements.

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CONSOLIDATED STATEMENTS OF REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ EQUITY
(In thousands, except share amounts) 

Series A Redeemable Convertible
Preferred Stock

Common Stock

Additional Paid-In

Accumulated Other
Comprehensive

Accumulated

Shares

Amount

Shares

Amount

Capital

Income

Deficit

Total

BALANCE, December 31, 2015, as adjusted

14,666,667  $

28,602 

75,820,307  $

76  $

231,497  $

—  $

(23,051) $

208,522 

Common stock issuance ESPP plan

— 

— 

Redemption of Series A Preferred Stock

(8,066,667)

(55,000)

Stock issuance fees and expenses

Issuance of restricted stock

Issuance of stock for warrant exercise

Issuance of common stock for stock options

Beneficial conversion feature reversal

Deemed dividends on preferred stock

Change in beneficial conversion feature

Stock compensation expense - warrants

Stock compensation expense - options and
restricted stock

Net loss

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

24,596 

18,011 

6,663 

— 

— 

— 

98,672 

— 

— 

43,332 

165,375 

2,443,472 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

3 

— 

— 

— 

— 

— 

— 

736 

— 

(267)

— 

— 

3,296 

(24,596)

— 

— 

460 

4,978 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

(18,011)

(6,663)

— 

— 

(6,142)

736 

— 

(267)

— 

— 

3,299 

(24,596)

(18,011)

(6,663)

460 

4,978 

(6,142)

BALANCE, December 31, 2016, as adjusted

6,600,000  $

22,873 

78,571,158  $

79  $

216,104  $

—  $

(53,867) $

162,316 

Common stock issuance ESPP plan

Issuance of Series A Preferred Stock

Stock issuance fees and expenses

Foreign currency translation adjustments

Gain on effective cash flow hedge

Issuance of restricted stock

Issuance of stock for warrant exercise

Issuance of common stock for stock options

Deemed dividends on preferred stock

Amortization of beneficial conversion feature

ESPP expense

Adjustment for impact of accounting standard

Stock comp. exp. - options and restricted stock

Net loss

December 31, 2017, as adjusted

Common stock issuance ESPP plan

— 

264,000 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

6,864,000 

— 

— 

— 

— 

— 

— 

— 

— 

— 

3,645 

6,097 

— 

— 

— 

— 

32,615 

— 

Redemption of Series A Preferred Stock

(6,864,000)

(50,096)

Stock issuance fees and expenses

Foreign currency translation adjustments

Loss on effective cash flow hedge

Issuance of common stock - Acquisition

Issuance of common stock - Public Offering

Issuance of restricted stock

Issuance of common stock for stock options

Deemed dividends on preferred stock

Amortization of beneficial conversion feature

Gain on redemption of preferred stock

ESPP Expense

Stock comp. exp.- options and restricted stock

Adjustment for impact of accounting standard

Net income

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

BALANCE, December 31, 2018

—  $

— 

— 

— 

— 

— 

— 

— 

10,198 

(1,792)

9,075 

— 

— 

— 

— 

— 

108,599 

— 

— 

— 

— 

822,711 

364,600 

595,506 

— 

— 

— 

— 

— 

— 

80,462,574 

117,146 

— 

— 

— 

— 

999,994 

11,270,000 

62,182 

1,553,544 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

1 

— 

— 

— 

— 

— 

— 

— 

— 

80 

— 

— 

— 

— 

— 

1 

11 

— 

2 

— 

— 

— 

— 

— 

— 

— 

844 

— 

(218)

— 

— 

4,094 

— 

1,960 

— 

805 

96 

— 

6,345 

— 

230,030 

1,050 

— 

(354)

— 

— 

13,242 

135,060 

(297)

8,596 

— 

(20,929)

— 

243 

6,640 

(1,095)

— 

— 

— 

— 

44 

230 

— 

— 

— 

— 

— 

— 

— 

— 

— 

274 

— 

— 

— 

(68)

(785)

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

— 

(3,645)

(6,902)

— 

6,388 

— 

(396)

(58,422)

— 

— 

— 

(54)

— 

— 

— 

— 

— 

(10,198)

4,571 

9,075 

— 

— 

1,130 

2,640 

844 

— 

(218)

44 

230 

4,095 

— 

1,960 

(3,645)

(6,097)

96 

6,388 

6,345 

(396)

171,962 

1,050 

— 

(354)

(122)

(785)

13,243 

135,071 

(297)

8,598 

(10,198)

(16,358)

9,075 

243 

6,640 

35 

2,640 

94,465,440  $

94  $

372,186  $

(579) $

(51,258) $

320,443 

See notes to consolidated financial statements.

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CONSOLIDATED STATEMENTS OF CASH FLOWS
(In thousands)

CASH FLOWS FROM OPERATING ACTIVITIES

Net Income (loss)
Adjustments to reconcile net income (loss) to net cash provided by
operating activities, net of business acquisition:

Depreciation
Impairment/loss on sale of assets
Loss on sale of business
Amortization of intangibles
Loss on extinguishment of debt
Amortization of debt issue costs
Stock based compensation

Changes in assets and liabilities, net of business acquisition:

(Increase) decrease in accounts receivable, net of write-offs
(Increase) decrease in inventories
(Increase) decrease in other assets
(Increase) decrease in other current assets
Increase (decrease) in accounts payable and other liabilities

Net cash provided by operating activities

CASH FLOWS FROM INVESTING ACTIVITIES

Acquisition, net of cash acquired
Purchases of property and equipment

Net cash used in investing activities

CASH FLOWS FROM FINANCING ACTIVITIES

(Payments) advances from revolving credit facility, net
Repayment of capital lease obligations
Proceeds from term loan
Redemption of preferred stock
Repayment of term loan
Payments of debt issue costs
Issuance of common stock, net

Net cash (used in) provided by financing activities

Effects of foreign exchange rate changes on cash and cash equivalents

Net increase (decrease) in cash and cash equivalents

Cash and cash equivalent, beginning of year

Cash and cash equivalents, end of year

Supplemental disclosure of cash flow information:

Interest paid
Income taxes paid (refunded), net

Supplemental disclosure of non-cash investing and financing information:

Equipment acquired under capital lease/loan obligations
Purchases of property and equipment included in accounts payable
Fair value of common stock issued to fund acquisition
Fair value of restricted stock issued to fund purchase of customer list

For the years ended December 31,

2018

2017 
(as adjusted)

2016 
(as adjusted)

$

2,640  $

(396) $

(6,142)

15,804 
404 
— 
5,928 
— 
542 
6,955 

209 
734 
96 
(1,448)
12,922 

44,786 

(125,377)
(14,310)

(139,687)

(20,400)
(6,563)
30,000 
(50,096)
(4,500)
(576)

144,094 

91,959 

(68)

(3,010)
12,821 

15,596 
253 
1,058 
6,995 
— 
440 
6,441 

(5,594)
(1,423)
(29)
(446)
(4,858)

18,037 

— 
(13,690)

(13,690)

2,496 
(5,424)
— 
— 
(3,753)
— 

2,586 

(4,095)

44 

296 
12,525 

$

$

9,811  $

12,821  $

6,511  $
(31)

7,569 
660 
13,243 
— 

5,155  $
284 

5,728 
495 
— 
4,095 

15,937 
3,464 
— 
7,272 
1,099 
3,497 
5,438 

(6,569)
(1,145)
(44)
165 
(1,495)

21,477 

1,035 
(7,536)

(6,501)

12,856 
(5,293)
75,000 
(55,000)
(55,000)
(2,202)

3,768 

(25,871)

— 

(10,895)
23,420 

12,525 

5,423 
290 

6,057 
2,423 
— 
— 

See notes to consolidated financial statements.

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NOTES TO THE FINANCIAL STATEMENTS
December 31, 2018, 2017 and 2016

Note A – Nature of Business and Basis of Presentation

NeoGenomics,  Inc.,  a  Nevada  corporation  (the  “Parent”,  “Company”,  or  “NeoGenomics”),  and  its  subsidiaries  operates  as  a  certified  high  complexity  clinical  laboratory  in
accordance  with  the  federal  government’s  Clinical  Laboratory  Improvement Act,  as  amended  (“CLIA”),  and  is  dedicated  to  the  delivery  of  clinical  diagnostic  services  to
pathologists, oncologists, urologists, hospitals, and other laboratories as well as providing clinical trial services to pharmaceutical firms.

The accompanying consolidated financial statements include the accounts of the Parent, all subsidiaries, and the accounts of any variable interest entities where the Company
has determined it is the primary beneficiary. All significant intercompany accounts and balances have been eliminated in consolidation.  

Segment Reporting

The  Company  reports  its  activities  in two  operating  segments;  the  Clinical  Services  segment  and  the  Pharma  Services  segment.    These  reportable  segments  deliver  testing
services to hospitals, pathologists, oncologists, clinicians, pharmaceutical firms and researchers and represent 100% of the Company’s consolidated assets, net revenues and net
income for each of the three years ended December 31, 2018, 2017 and 2016, respectively.  For further financial information about these segments, see Note R.

Reclassifications

Certain  reclassifications  have  been  made  to  the  prior  period  financial  statements  to  conform  to  the  current  period  presentation.  In  addition,  the  Company  adopted  the  new
revenue recognition accounting standard on a full retrospective basis, which requires the Company to restate certain previously reported results. For further details regarding the
impact of these new accounting standards see Note B.

Note B – Summary of Significant Accounting Policies

Use of Estimates

The  Company  prepares  its  consolidated  financial  statements  in  conformity  with  accounting  principles  generally  accepted  in  the  United  States  of America  (“GAAP”).  These
principles  require  management  to  make  estimates,  judgments  and  assumptions  that  affect  the  reported  amounts  of  assets,  liabilities,  revenues  and  expenses,  together  with
amounts  disclosed  in  the  related  notes  to  the  consolidated  financial  statements.  Actual  results  and  outcomes  may  differ  from  management’s  estimates,  judgments  and
assumptions. Significant estimates, judgments and assumptions used in these consolidated financial statements include, but are not limited to those related to revenues, accounts
receivable  and  related  allowances,  contingencies,  useful  lives  and  recovery  of  long-term  assets  and  intangible  assets,  income  taxes  and  valuation  allowances,  stock-based
compensation and impairment analysis of goodwill. These estimates, judgments, and assumptions are reviewed periodically and the effects of material revisions in estimates are
reflected in the consolidated financial statements prospectively from the date of the change in estimate.

Revenue Recognition

Clinical Services

The  Company’s  specialized  diagnostic  services  are  performed  based  on  a  written  test  requisition  form  or  electronic  equivalent.  The  performance  obligation  is  satisfied  and
revenues are recognized once the diagnostic services have been performed and the results have been delivered to the ordering physician. These diagnostic services are billed to
various  payers,  including  Medicare,  commercial  insurance  companies,  other  directly  billed  healthcare  institutions  such  as  hospitals  and  clinics,  and  individuals.  Revenue  is
recorded  for  all  payers  based  on  the  amount  expected  to  be  collected,  which  considers  implicit  price  concessions.  Implicit  price  concessions  represent  differences  between
amounts  billed  and  the  estimated  consideration  the  Company  expects  to  receive  based  on  negotiated  discounts,  historical  collection  experience  and  other  anticipated
adjustments, including anticipated payer denials. Collection of consideration the Company expects to receive typically occurs within 30  to 60 days of billing for commercial
insurance, Medicare and other governmental and self-pay payers and within 60 to 90 days of billing for client payers.

Pharma Services

The Company’s Pharma Services segment generally enters into contracts with pharmaceutical and biotech customers as well as other Clinical Research Organizations (“CROs”)
to provide research and clinical trial services ranging in duration from one month to several years. The Company records revenue on a unit-of-service basis based on number of
units completed and the

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total expected contract value. The total expected contract value is estimated based on historical experience of total contracted units compared to realized units as well as known
factors on a specific contract-by-contract basis. Certain contracts include upfront fees, final settlement amounts or billing milestones that may not align with the completion of
performance obligations. The value of these upfront fees or final settlement amounts is usually recognized over time based on the number of units completed, which aligns with
the progress of the Company towards fulfilling its obligations under the contract.

The Company also enters into other contracts, such as validation studies, for which the sole deliverable is a final report that is sent to sponsors at the completion of contracted
activities.  For  these  contracts,  revenue  is  recognized  at  a  point  in  time  upon  delivery  of  the  final  report  to  the  sponsor. Any  contracts  that  contain  multiple  performance
obligations  and  include  both  units-of-service  and  point  in  time  deliverables  are  accounted  for  as  separate  performance  obligations  and  revenue  is  recognized  as  previously
disclosed. The Company negotiates billing schedules and payment terms on a contract-by-contract basis. While the contract terms generally provide for payments based on a
unit-of-service arrangement, the billing schedules, payment terms and related cash payments may not align with the performance of services and, as such, may not correspond to
revenue recognized in any given period.

Amounts collected in advance of services being provided are deferred as contract liabilities. The associated revenue is recognized and the contract liability is reduced as the
contracted services are subsequently performed. Contract assets are established for revenue that has been recognized but not yet billed. These contract assets are reduced once
the customer is invoiced and a corresponding account receivable is recorded. Additionally, certain costs to obtain contracts, primarily for sales commissions, are capitalized
when incurred and are amortized over the term of the contract. Amounts capitalized for contracts with an initial contract term of twelve months or less are classified as current
assets and all others are classified as non-current assets. Contract assets are included in other assets on the consolidated balance sheet.

Most contracts are terminable by the customer, either immediately or according to advance notice terms specified within the contracts.  All contracts require payment of fees to
the Company for services rendered through the date of termination and may require payment for subsequent services necessary to conclude the study or close out the contract. 

Cost of Revenue

Cost of revenue includes payroll and payroll related costs for performing tests, depreciation of laboratory equipment, rent for laboratory facilities, laboratory reagents, probes
and supplies, and delivery and courier costs relating to the transportation of specimens to be tested.

Shipping Costs
The Company has a significant expense related to shipping specimens to our facilities for testing, including costs incurred for contract couriers, commercial airline flights and
charges  from  FedEx  charges.  We  also  incur  expenses  returning  samples  and  slides  to  our  clients.    We  had  approximately  $9.8 million, $10.8  million  and $10.3  million  in
outsourced shipping expenses for the years ended December 31, 2018, 2017 and 2016, respectively. These costs were expensed as fulfillment costs and included in our cost of
revenue.

Advertising Costs

Advertising costs are expensed at the time they are incurred and are not material for the years ended December 31, 2018, 2017 and 2016. 

Research and Development

Research and development (“R&D”) costs are expensed as incurred. R&D expenses consist of payroll, employee benefits, equity compensation, inventory, and payment for
samples to complete validation studies. These expenses are primarily incurred to develop new genetic tests.

Accounts Receivable

Accounts  receivable  are  reported  for  all  clinical  services  payers  based  on  the  amount  expected  to  be  collected,  which  considers  implicit  price  concessions.  Implicit  price
concessions represent differences between amounts billed and the estimated consideration the Company expects to receive based on negotiated discounts, historical collection
experience and other anticipated adjustments, including anticipated payer denials.

For Pharma Services, the Company negotiates billing schedules and payment terms on a contract-by-contract basis which often includes payments based on certain milestones
being achieved. Receivables are generally reported over time based on the number of units completed, which aligns with the progress of the Company towards fulfilling its
obligations under the contract.

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Foreign Currency

In  2018,  due  to  a  change  in  strategy  regarding  the  negotiation  of  contracts,  the  Company  changed  the  functional  currency  for  our  subsidiaries  outside  of  the  U.S.  from  the
applicable  local  currency  to  U.S.  dollars.    Prior  to  the  change,  we  translated  the  financial  statements  of  the  subsidiary  into  U.S.  dollars  using  average  monthly  exchange
rates.  Translation gains and losses were recorded in accumulated other comprehensive income (“AOCI”) as a component of stockholders' equity.

Statements of Cash Flows

For purposes of the consolidated statements of cash flows, we consider all highly liquid investments purchased with an original maturity of three months or less to be cash
equivalents.

Fair Value of Financial Instruments

The carrying value of cash and cash equivalents, accounts receivable, accounts payable, accrued expenses and other liabilities, and other current assets and liabilities, including
our  revolving  credit  facility  are  considered  reasonable  estimates  of  their  respective  fair  values  due  to  their  short-term  nature.  The  Company  maintains  its  cash  and  cash
equivalents with financial institutions that the Company believes to be of high credit standing. The Company believes that, as of December 31, 2018, its concentration of credit
risk related to cash and cash equivalents was not significant. The carrying value of the Company’s long-term capital lease obligations and term debt approximates its fair value
based on the current market conditions for similar instruments.  In December of 2016 and June of 2018, the Company entered into interest rate swap agreements. See Derivative
Instruments and Hedging Activities below for additional discussion.   

Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the
asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value must maximize the use of
observable inputs and minimize the use of unobservable inputs. A fair value hierarchy has been established based on three levels of inputs, of which the first two are considered
observable and the last unobservable.

Level 1: Quoted prices in active markets for identical assets or liabilities.  These are typically obtained from real-time quotes for transactions in active exchange markets
involving identical assets.

Level 2: Inputs, other than quoted prices included within Level 1, which are observable for the asset or liability, either directly or indirectly.  These are typically obtained from
readily-available pricing sources for comparable instruments.

Level 3: Unobservable inputs, where there is little or no market activity for the asset or liability.  These inputs reflect the reporting entity’s own assumptions of the data that
market participants would use in pricing the asset or liability, based on the best information available in the circumstances.

Inventories

Inventories, which consist principally of testing supplies, are valued at lower of cost or net realizable value, using the first-in, first-out method (FIFO).

Other Current Assets

As of December 31, 2018, 2017 and 2016, other current assets consist primarily of pharma contract assets and capitalized commissions.

Property and Equipment

Property and equipment are recorded at cost, net of accumulated depreciation and amortization. Depreciation and amortization are computed on the straight-line basis over the
estimated useful lives of the assets. Leasehold improvements and property and equipment under capital leases are amortized over the shorter of the related lease terms or their
estimated useful lives. Costs incurred in connection with the development of internal-use software are capitalized in accordance with the accounting standard for internal-use
software, and are amortized over the expected useful life of the software, generally 2-5 years.  We perform a fair value assessment on property and equipment acquired in a
business combination and record the fair value as the cost basis for those assets.

The Company periodically reviews the estimated useful lives of property and equipment. Changes to the estimated useful lives are recorded prospectively from the date of the
change. Upon retirement or sale, the cost of the assets disposed of and the

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related accumulated depreciation are removed from the accounts and any resulting gain or loss is included in income (loss) from operations. Repairs and maintenance costs are
expensed as incurred. 

Intangible Assets

Intangible assets with determinable useful lives are recorded at fair value or cost, less accumulated amortization. Each intangible asset is amortized over its estimated service
period using the straight-line method. We periodically review the estimated pattern in which the economic benefits will be consumed and adjust the amortization period and
pattern to match our estimate. Intangible assets with indefinite useful lives are recorded at fair value or cost and not amortized but tested annually for impairment.

At December 31, 2018, the Company’s intangible assets were related to customer relationships, trade names and trademarks acquired through acquisitions, as well as customer
relationships and a non-compete agreement related to the purchase of a customer list.    

Goodwill

The  Company  evaluates  goodwill  on  an  annual  basis  in  the  fourth  quarter  or  more  frequently  if  management  believes  indicators  of  impairment  exist.  Such  indicators  could
include, but are not limited to (1) a significant adverse change in legal factors or in business climate, (2) unanticipated competition, or (3) an adverse action or assessment by a
regulator. The Company first assesses qualitative factors to determine whether it is more likely than not that the fair value of a reporting unit is less than its carrying amount,
including  goodwill.  If  management  concludes  that  it  is  more  likely  than  not  that  the  fair  value  of  a  reporting  unit  is  less  than  its  carrying  amount,  management  performs  a
quantitative goodwill impairment test. The quantitative analysis is performed by s comparing the fair value of the reporting unit to its carrying value. If the carrying value is
greater than our estimate of fair value, an impairment loss will be recognized for the amount in which the carrying amount exceeds the reporting units fair value. The Company
estimates  the  fair  values  of  its  reporting  units  using  a  combination  of  the  income,  or  discounted  cash  flows,  approach  and  the  market  approach,  which  utilizes  comparable
companies’ data. The Company’s evaluation of goodwill completed during the fourth quarter resulted in no impairment losses.

Recoverability and Impairment of Long-Lived Assets

The Company reviews the recoverability of its long-lived assets (including definite-lived intangible assets) if events or changes in circumstances indicate the assets may be
impaired.  Evaluation  of  possible  impairment  is  based  on  the  Company’s  ability  to  recover  the  asset  from  the  expected  future  pretax  cash  flows  (undiscounted  and  without
interest charges) of the related operations. If the expected undiscounted pretax cash flows are less than the carrying amount of such asset, an impairment loss is recognized for
the difference between the estimated fair value and carrying amount of the asset.  No impairment losses were recognized in the years ended December 31, 2018  or 2017.  The
Company recognized approximately $3.5 million in impairment losses for the year ended December 31, 2016.  See Note Q for further details.  

The Company performs an impairment test for its indefinite-lived intangible assets on an annual basis by reviewing the book value of the asset compared to the fair value. We
did  not  perform  an  impairment  analysis  for  the  year  ended  December  31,  2018  as  the  indefinite-lived  asset  was  acquired  in  December  of  2018  and  the  book  value  was
determined to approximate fair value due to the date acquired.

Debt Issuance Costs

We record debt issuance costs related to our term debt as direct deductions from the carrying amount of the debt.  The costs are amortized to interest expense over the life of the
debt  using  the  effective  interest  method.    Debt  issuance  costs  relating  to  line  of  credit  arrangements  will  be  recorded  as  assets  and  amortized  over  the  term  of  the  credit
arrangement regardless of whether any outstanding borrowing exists.

Derivative Instruments and Hedging Activities

The Company uses derivative instruments to manage risks related to interest expense.  We account for derivatives in accordance with Financial Accounting Standards Board
(“FASB”) ASC Topic 815, which establishes accounting and reporting standards requiring that derivative instruments be recorded on the balance sheet as either an asset or
liability and measured at fair value.  Additionally, changes in the derivative's fair value will be recognized currently in earnings unless specific hedge accounting criteria are
met. For further information on derivative instruments and hedging activities, see Note H.   

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Series A Redeemable Convertible Preferred Stock

The Company classified its Series A Redeemable Convertible Preferred Stock (“Series A Preferred Stock”) as temporary equity on the consolidated balance sheet due to certain
deemed  liquidation  events  that  were  outside  the  Company’s  control.  We  evaluated  our  Series A  Preferred  Stock  upon  issuance  in  order  to  determine  classification  as  to
permanent  or  temporary  equity  and  whether  or  not  the  instrument  contains  an  embedded  derivative  that  requires  bifurcation.  This  analysis  followed  the  whole  instrument
approach  which  compares  an  individual  feature  against  the  entire  instrument  which  includes  that  feature.  This  analysis  was  based  on  a  consideration  of  the  economic
characteristics and risk of the Series A Preferred Stock.

We  evaluated  all  of  the  stated  and  implied  substantive  terms  and  features,  including:  (i)  redemption  (Purchase  Call  Option)  on  the  Series A  Preferred  Stock  allowing  the
Company to redeem the Series A Preferred Stock at any time, (ii) required redemption contingent if we raise capital, (iii) required redemption in the event of certain deemed
liquidation events (in essence, any change in control of the Company), (iv) conversion (Written Call Option) on the underlying shares if after three years the stock trades at
$8.00 for thirty trading days, and (v) conversion (Contingent Forward) on the underlying shares automatically at the ten year anniversary of the issue date.  

As a result of this analysis, we concluded that the Series A Preferred Stock represented an equity host and, therefore, the redemption feature of the Series A Preferred Stock was
not  considered  to  be  clearly  and  closely  related  to  the  associated  equity  host  instrument.    However,  the  redemption  features  did  not  meet  the  net  settlement  criteria  of  a
derivative and, therefore, were not considered embedded derivatives that required bifurcation.

We also concluded that the conversion rights under the Series A Preferred Stock were clearly and closely related to the equity host instrument.  Accordingly, the conversion
rights features on the Series A Preferred Stock were not considered an embedded derivative that required bifurcation.

Beneficial Conversion Feature

The issuance of the Company's Series A Preferred Stock generated a beneficial conversion feature, which arises when a debt or equity security is issued with an embedded
conversion option that is beneficial to the investor or in the money at inception because the conversion option has an effective strike price that is less than the market price of the
underlying stock at the commitment date. We recognized this beneficial conversion feature by allocating the intrinsic value of the conversion option, which is the number of
shares of common stock available upon conversion multiplied by the difference between the effective conversion price per share and the fair value of common stock per share
on the commitment date, to additional paid-in capital, resulting in a discount on the Series A Preferred Stock. NeoGenomics accreted the discount from the date of issuance
through  the  earliest  conversion  date,  which  was  three  years.   Accretion  expense  was  recognized  as  dividend  equivalents.  On  June  25,  2018,  the  Company  redeemed  the
remaining outstanding Preferred Stock. For further information on the redemption, see Note I.   

Income Taxes

We compute income taxes in accordance with ASC Topic 740, Income Taxes, under which deferred taxes are recognized for the tax consequences of temporary differences by
applying enacted statutory rates applicable to future years to differences between the financial statement carrying amounts and the tax bases of existing assets and liabilities.
Also, the effect on deferred taxes of a change in tax rates is recognized in income in the period that included the enactment date. Temporary differences between financial and
tax reporting arise primarily from the use of different depreciation methods and lives for property and equipment and recognition of bad debts and various other expenses that
have been allowed for or accrued for financial statement purposes but are not currently deductible for income tax purposes.

The provision for income taxes, including the effective tax rate and analysis of potential tax exposure items, if any, requires significant judgment and expertise in federal and
state income tax laws, regulations and strategies, including the determination of deferred tax assets and liabilities and any estimated valuation allowances deemed necessary to
recognize deferred tax assets at an amount that is more likely than not to be realized. We evaluate tax positions that have been taken or are expected to be taken in our tax
returns, and record a liability for uncertain tax positions, if deemed necessary. We follow a two-step approach to recognizing and measuring uncertain tax positions. First, tax
positions are recognized if the weight of available evidence indicates that it is more likely than not that the position will be sustained upon examination, including resolution of
related appeals or litigation processes, if any. Second, the tax position is measured as the largest amount of tax benefit that has a greater than 50% likelihood of being realized
upon settlement.

We recognize interest and penalties related to unrecognized tax benefits in the provision for income taxes in the accompanying consolidated financial statements. During  the
year ended December 31, 2018 we had an insignificant amount on our balance sheet related to uncertain tax positions including a provision for interest and penalties related to
such positions. During the

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years ended December 31, 2017 and 2016, we do not believe we had any significant uncertain tax positions, nor did we have any provision for interest or penalties related to
such positions. We do not expect a significant change in our uncertain tax positions in the next 12 months.

Stock-Based Compensation

We  measure  compensation  expense  for  stock-based  awards  to  employees,  non-employee  contracted  physicians,  and  directors  based  upon  the  awards’  initial  grant-date  fair
value.  The estimated grant-date fair value of the award is recognized as expense over the requisite service period using the straight-line method.

We estimate the fair value of stock options and warrants using a trinomial lattice model. This model is affected by our stock price on the date of the grant as well as assumptions
regarding a number of highly complex and subjective variables. These variables include the expected term of the option, expected risk-free rates of return, the expected volatility
of  our  common  stock,  and  expected  dividend  yield,  each  of  which  is  more  fully  described  below.  The  assumptions  for  expected  term  and  expected  volatility  are  the  two
assumptions that significantly affect the grant date fair value.

Expected Term: The expected term of an option is the period of time that the option is expected to be outstanding. The average expected term is determined using a trinomial
lattice simulation model.

Risk-free Interest Rate: We base the risk-free interest rate used in the trinomial lattice valuation method on the implied yield at the grant date of the U.S. Treasury zero-coupon
issue  with  an  equivalent  term  to  the  stock-based  award  being  valued.  Where  the  expected  term  of  a  stock-based  award  does  not  correspond  with  the  term  for  which  a  zero
coupon interest rate is quoted, we use the nearest interest rate from the available maturities.

Expected Stock Price Volatility: We use our own historical weekly volatility because that is more reflective of market conditions.

Dividend Yield: Because we have never paid a dividend and do not expect to begin doing so in the foreseeable future, we have assumed no dividend yield in valuing our stock-
based awards.

Tax Effects of Stock-Based Compensation

We will only recognize a tax benefit from windfall tax deductions for stock-based awards in additional paid-in capital if an incremental tax benefit is realized after all other tax
attributes  currently  available  have  been  utilized. Excess  tax  benefits  and  tax  deficiencies  for  share-based  payment  awards  are  recorded  within  income  tax  expense  in  the
consolidated statement of income (loss), rather than directly to additional paid-in capital.

Net Income (Loss) per Common Share

We have adopted the two class method of calculating earnings (loss) per share, due to the issuance of the Series A Preferred Stock in December 2015.  Under this method, when
we have a net loss we will not allocate the net loss to the holders of the Series A Preferred Stock (our participating shareholders) as they do not have a contractual obligation to
share in losses.  Under this method, when we have net income, we will compute net income per share using the weighted average number of common shares outstanding during
the applicable period plus the weighted average number of preferred shares outstanding during the period.  

Diluted net income per share is computed using the weighted average number of common shares outstanding during the applicable period, plus the dilutive effect of potential
common stock. Potential common stock consists of shares issuable pursuant to stock options and warrants. Calculations of net income per share are done using the treasury
stock method.

Recently Adopted and Issued Accounting Guidance

Adopted
In June 2018, the FASB issued ASU 2018-07, Compensation - Stock Compensation. This standard expands the scope of current stock compensation recognition standards to
include share-based payment transactions for acquiring goods and services from nonemployees. ASU 2018-07 is effective for fiscal years beginning after December 15, 2018,
including  interim  periods  within  that  fiscal  year,  with  early  adoption  permitted.  The  Company  early  adopted  this  ASU  on  April  1,  2018.  The  adoption  of  this  standard
substantially aligned the accounting for share based payments to employees and nonemployees. Under the new standard, the Company recorded a cumulative adjustment of
$1.1 million to increase retained earnings and decrease APIC.

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In August  2017,  the  FASB  issued ASU  2017-12, Derivatives  and  Hedging. This standard refines hedge accounting to better align an entity’s risk management activities and
financial reporting for hedging relationships through changes to both the designation and measurement guidance for qualifying hedging relationships and the presentation of
hedge  results.  The  amended  guidance  also  expands  items  eligible  for  hedge  accounting  and  simplifies  the  hedge  effectiveness  testing. ASU  2017-12  is  effective  for  annual
periods beginning after December 15, 2018 and interim periods within those annual periods. Early adoption is permitted. The Company early adopted this standard on April 1,
2018 and applied this guidance to the cash flow hedge entered into in June 2018, see Note H. The adoption of ASU 2017-12 did not have a material effect on the consolidated
financial statements.

In May 2014, the FASB issued ASU 2014-09, which amends FASB Accounting Standards Codification by creating Topic 606, Revenues from Contracts with Customers.  This
standard  update  calls  for  a  number  of  revisions  in  the  revenue  recognition  rules.  The  Company  adopted  this ASU  on  January  1,  2018  using  a  full  retrospective  method  of
adoption. Under this method, the Company has restated its results for each prior reporting period presented as if ASC 606 had been effective for those periods.

The adoption of this standard required us to implement new revenue policies, procedures and internal controls related to revenue recognition. In addition, the adoption resulted
in enhanced financial statement disclosures surrounding the nature, amount, timing and uncertainty of revenue and cash flows arising from contracts with customers. For further
details, see Note C.

The new standard impacts each of our two reportable segments differently due to the transactional nature of the Clinical Services segment versus the generally long-term nature
of our Pharma Services segment contracts. The specific effect on our reportable segments is explained below:

Clinical Services Revenue

Under the new standard, substantially all of our bad debt expense, which has historically been presented as part of general and administrative expense, is considered an implicit
price concession and is reported as a reduction in revenue. As a result of ASC 606, we reported a material cumulative reduction in clinical revenue from previously reported
periods and a similar reduction in general and administrative expenses.

Pharma Services Revenue

The adoption of ASC 606 also resulted in changes to the timing of revenue recognition related to Pharma Services contracts as certain individual deliverables such as study
setup fees, for which revenue was previously recognized in the period when the deliverables were completed and invoiced, will be recognized over the remaining performance
period under the new standard. Additionally, certain costs to obtain contracts, primarily for sales commissions, are capitalized when incurred and are amortized over the term of
the contract. Under ASC 606, the Company is required to make estimates of the total transaction price per contract, including estimates of variable consideration and the number
of performance obligations, and recognize the estimated amount as revenue as it transfers control of the product or performance obligations to its customers. The estimation of
total  transaction  price,  number  of  performance  obligations,  variable  consideration  and  the  application  of  the  related  constraint,  was  not  required  under  previous  GAAP  and
requires the use of significant management judgment and estimates. The Company elected certain practical expedients as allowed under the standard including the following:
contracts that began and ended within the same annual reporting period were not restated; contracts with variable consideration were estimated using the transaction price at the
date the contract was completed; contract modifications that occurred prior to the earliest reporting period have not been retrospectively restated but have rather been reflected
as an aggregate adjustment in the earliest reporting period. The cumulative effect of this standard did not result in a material change to our Pharma Services revenue.

 ASC 606 Adoption Impact to Previously Reported Results

We adjusted our condensed consolidated financial statements from amounts previously reported due to the adoption of ASC 606.

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Select condensed consolidated balance sheet line items, which reflect the adoption of ASC 606, are as follows (in thousands):

As Reported

December 31, 2017

Impact of Adoption

As Adjusted

Prepaids and other current assets
Other assets

Total Assets

Pharma contract liability
Long-term pharma contract liability
Deferred income tax liability, net
Stockholders' Equity

Total Liabilities and Stockholders' Equity

$

$

$

$

$

$

$

4,241 
689 

343,340 

— 
— 
6,307 
172,918 

343,340 

$

912 
202 

1,114 

1,406 
283 
381 
(956)

1,114 

$

$

$

$

Select condensed consolidated statement of operations line items, which reflect the adoption of ASC 606, are as follows (in thousands):

As Reported

Impact of Adoption

As Adjusted

For the Twelve Months Ended December 31, 2017

Net Revenue
Clinical Services
Pharma Services

Total Revenue
Gross Margin

Total operating expenses 
Income from Operations
Interest expense
Other expense
Income tax (benefit)

Net Loss

Net Revenue
Clinical Services
Pharma Services

Total Revenue
Gross Margin

Total operating expenses 
Income from Operations
Interest expense
Other expense
Income tax (benefit)

Net Loss

$

$

$

$

$

231,748 
26,863 

258,611 
120,316 

117,992 
2,324 
5,540 
265 
(2,635)

$

(18,651)
291 

(18,360)
(18,360)

(18,938)
578 
—
(253)
381 

(846)

$

450 

$

As Reported

Impact of Adoption

As Adjusted

For the Twelve Months Ended December 31, 2016

$

222,015 
22,068 

244,083 
110,379 

107,805 
2,574 
9,998 
— 
(1,701)

$

(11,856)
(419)

(12,275)
(12,275)

(11,856)
(419)
— 
— 
— 

(5,723)

$

(419)

$

76

5,153 
891 

344,454 

1,406 
283
6,688 
171,962 

344,454 

213,097 
27,154 

240,251 
101,956 

99,054 
2,902 
5,540 
12 
(2,254)

(396)

210,159 
21,649 

231,808 
98,104 

95,949 
2,155 
9,998 
— 
(1,701)

(6,142)

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NEOGENOMICS, INC.

In  May  2017,  the  FASB  issued  ASU  2017-09, Compensation  –  Stock  Compensation.  This  standard  provides  guidance  related  to  the  scope  of  stock  option  modification
accounting, to reduce diversity in practice and reduce cost and complexity regarding existing guidance. This update is effective for annual periods beginning after December 15,
2017. The Company adopted this standard on January 1, 2018. The adoption of this standard did not have an impact on the consolidated financial statements.

In January 2017, the FASB issued ASU No. 2017-04, Intangibles – Goodwill and Other: Simplifying the Test for Goodwill Impairment. This standard eliminates Step 2 of the
goodwill  impairment  test.  Instead,  an  entity  should  perform  its  annual  or  interim  goodwill  impairment  test  by  comparing  the  fair  value  of  a  reporting  unit  with  its  carrying
amount. An entity should recognize an impairment charge for the amount by which the carrying amount exceeds the reporting unit’s fair value; however, the loss recognized
should not exceed the total amount of goodwill allocated to that reporting unit. This update is effective for annual and interim periods beginning after December 15, 2019. The
Company early adopted this standard on January 1, 2018. The adoption of this standard did not have an impact on the consolidated financial statements.

In August 2016, the FASB issued ASU 2016-15, Statement of Cash Flows – Classification of Certain Cash Receipts and Cash Payments. This standard clarifies how specific
cash receipts and cash payments are classified and presented in the statement of cash flows. This update is effective for fiscal years and interim periods within those fiscal years
beginning after December 15, 2017. The Company adopted this standard on January 1, 2018. The adoption of this standard did not have an impact on the consolidated financial
statements.

In February 2016, the FASB issued ASU 2016-02, Leases. This standard was issued to increase transparency and comparability among organizations by recognizing lease assets
and lease liabilities, including for operating leases, on the balance sheet and disclosing key information about leasing arrangements. This update is effective for fiscal years, and
interim periods within those fiscal years, beginning after December 15, 2018. We adopted this standard on January 1, 2019 using a modified transition approach under which a
cumulative-effect adjustment to retained earnings will be recognized on the date of adoption.

The Company has implemented an information system and changed business processes in order to accumulate the appropriate data and calculate and record right-of-use assets,
lease liabilities and the related expense. We do not currently expect that the adoption will have a material impact on our results of operations; however, based on our portfolio of
operating  leases,  we  expect  to  recognize  approximately $8  -  $10  million  of  right-of-use  assets  and  corresponding  lease  liabilities  on  our  consolidated  balance  sheet  upon
adoption.

Note C – Revenue Recognition

The Company has two operating segments for which it recognizes revenue; Clinical Services and Pharma Services. Our Clinical Services segment provides various clinical
testing services to community-based pathology practices, hospital pathology labs and academic centers with reimbursement from various payers including client direct billing,
commercial insurance, Medicare and other government payers, and patients. Our Pharma Services segment supports pharmaceutical firms in their drug development programs
by providing testing services for clinical trials and research.

Clinical Services Revenue

The  Company’s  specialized  diagnostic  services  are  performed  based  on  a  written  test  requisition  form  or  electronic  equivalent.  The  performance  obligation  is  satisfied  and
revenues are recognized once the diagnostic services have been performed and the results have been delivered to the ordering physician. These diagnostic services are billed to
various  payers,  including  Medicare,  commercial  insurance  companies,  other  directly  billed  healthcare  institutions  such  as  hospitals  and  clinics,  and  individuals.  Revenue  is
recorded  for  all  payers  based  on  the  amount  expected  to  be  collected,  which  considers  implicit  price  concessions.  Implicit  price  concessions  represent  differences  between
amounts  billed  and  the  estimated  consideration  the  Company  expects  to  receive  based  on  negotiated  discounts,  historical  collection  experience  and  other  anticipated
adjustments, including anticipated payer denials. Collection of consideration the Company expects to receive typically occurs within 30 to 60 days of billing for commercial
insurance, Medicare and other governmental and self-pay payers and within 60 to 90 days of billing for client payers.

Pharma Services Revenue
The Company’s Pharma Services segment generally enters into contracts with pharmaceutical and biotech customers as well as other Contract Research Organizations
(“CROs”) to provide research and clinical trial services ranging in duration from one month to several years. The Company records revenue on a unit-of-service basis based on
number of units completed and the total expected contract value. The total expected contract value is estimated based on historical experience of total contracted units compared
to realized units as well as known factors on a specific contract-by-contract basis. Certain contracts include upfront fees, final settlement amounts or billing milestones that may
not align with the completion of performance obligations.

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The value of these upfront fees or final settlement amounts is usually recognized over time based on the number of units completed, which aligns with the progress of the
Company towards fulfilling its obligations under the contract.

The Company also enters into other contracts, such as validation studies, for which the sole deliverable is a final report that is sent to sponsors at the completion of contracted
activities.  For  these  contracts,  revenue  is  recognized  at  a  point  in  time  upon  delivery  of  the  final  report  to  the  sponsor. Any  contracts  that  contain  multiple  performance
obligations  and  include  both  units-of-service  and  point  in  time  deliverables  are  accounted  for  as  separate  performance  obligations  and  revenue  is  recognized  as  previously
disclosed. The Company negotiates billing schedules and payment terms on a contract-by-contract basis. While the contract terms generally provide for payments based on a
unit-of-service arrangement, the billing schedules, payment terms and related cash payments may not align with the performance of services and, as such, may not correspond to
revenue recognized in any given period.

Amounts collected in advance of services being provided are deferred as contract liabilities on the balance sheet. The associated revenue is recognized and the contract liability
is reduced as the contracted services are subsequently performed. Contract assets are established for revenue that has been recognized but not yet billed. These contract assets
are reduced once the customer is invoiced and a corresponding account receivable is recorded. Additionally, certain costs to obtain contracts, primarily for sales commissions,
are  capitalized  when  incurred  and  are  amortized  over  the  term  of  the  contract. Amounts  capitalized  for  contracts  with  an  initial  contract  term  of  twelve  months  or  less  are
classified as current assets and all others are classified as non-current assets.

Most contracts are terminable by the customer, either immediately or according to advance notice terms specified within the contracts.  All contracts require payment of fees to
the Company for services rendered through the date of termination and may require payment for subsequent services necessary to conclude the study or close out the contract.

The following table summarizes the values of contract assets, capitalized commissions and contract liabilities as of December 31, 2018 and December 31, 2017 (in thousands):

Current pharma contract asset
Long-term pharma contract asset

Total pharma contract asset

Current pharma capitalized commissions
Long-term pharma capitalized commissions

Total pharma capitalized commissions

Current pharma contract liability
Long-term pharma contract liability

Total pharma contract liability

December 31, 2018

December 31, 2017 
(as adjusted)

$

$

$

$

$

$

86 
268 

354 

271 
650 

921 

927 
1,652 

2,579 

$

$

$

$

$

$

541 
31 

572 

371 
171 

542 

1,406 
283 

1,689 

There were no significant changes in the contract assets for the period ended December 31, 2018 as compared to the balances at December 31, 2017. Pharma contract liabilities
increased $0.9 million, or 53%, from December 31, 2017 while capitalized commissions also increased by $0.4 million, or 70%. These increases are due to higher upfront fees
driven  by  increases  in  the  volume  of  Pharma  contracts  in  process.  Revenue  recognized  for  the  year  ended December  31,  2018  related  to  Pharma  contract  liability  balances
outstanding at the beginning of the period was $1.6 million. Amortization of capitalized commissions for the year ended December 31, 2018 was $1.0 million.

There were no significant changes in the contract assets or contract liabilities for the period ended December 31, 2017 as compared to the balances at December 31, 2016.

At December 31, 2018, we had signed contracts for approximately $65.0 million, substantially all of which contain cancellation provisions. The Company applied the practical
expedient  and  does  not  disclose  information  about  remaining  performance  obligations  that  have  original  expected  durations  of  one  year  or  less.  The  unsatisfied  existing
performance obligations under long-term contracts as defined by ASC 606 differs from backlog in that it does not include wholly unperformed contracts where the promised
consideration is variable and/or the application of other practical expedients.

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Disaggregation of Revenue

The  Company  considered  various  factors  for  both  its  Clinical  Services  and  Pharma  Services  segments  in  determining  appropriate  levels  of  homogeneous  data  for  its
disaggregation of revenue, including the nature, amount, timing and uncertainty of revenue and cash flows. For Clinical Services, the categories identified align with our type of
customer due to similarities of billing method, level of reimbursement and timing of cash receipts at this level. Unbilled amounts are accrued and allocated to payor categories
based on historical experience. In future periods, actual billings by payor category may differ from accrued amounts. Pharma Services revenue was not further disaggregated as
substantially  all  of  our  revenue  relates  to  contracts  with  large  pharmaceutical  and  biotech  customers  as  well  as  other  CROs  for  which  the  nature,  timing  and  uncertainty  of
revenue and cash flows is similar and primarily driven by individual contract terms.

The following table details the disaggregation of revenue for both the Clinical and Pharma Services Segments (in thousands):

Clinical Services:
Client direct billing
Commercial Insurance
Medicare and Medicaid
Self-Pay

Total Clinical Services
Pharma Services:

Total Revenue

December 31, 2018

December 31, 2017 
(as adjusted)

December 31, 2016 
(as adjusted)

$

$

164,888  $
40,360 
35,566 
1,059 

241,873 
34,868 

276,741  $

147,726  $
35,473 
29,493 
405 

213,097 
27,154 

240,251  $

126,288 
52,801 
30,517 
553 

210,159 
21,649 

231,808 

Note D – Property and Equipment, Net

Property and equipment consisted of the following at December 31, 2018 and 2017 (in thousands):

Equipment
Building
Leasehold improvements
Furniture and fixtures
Computer hardware and office equipment
Computer software
Land
Assets not yet placed in service

Subtotal

Less: accumulated depreciation and amortization

Property and equipment, net

2018

2017

Estimated Useful
Lives in Years

$

$

43,164  $
7,400 
22,207 
5,675 
12,137 
14,341 
3,170 
2,921 

111,015 
(50,127)

60,888  $

33,711 
— 
14,517 
4,486 
10,038 
10,331 
— 
3,951 

77,034 
(40,530)

36,504 

3-10
40
2-20
7-10
3-10
2-5
— 
— 

Depreciation and amortization expense on property and equipment, including leased assets in each period was as follows (in thousands): 

Depreciation and amortization expense

$

15,804  $

15,596  $

15,937 

For the years ended December 31,

2018

2017

2016

In our consolidated statements of operations, we recorded depreciation and amortization expense as follows: $8.2 million, $9.3 million and $11.8 million was recorded in cost of
revenue  for  the  years  ended December  31,  2018, 2017  and 2016,  respectively,  and $7.6 million, $6.2 million  and $4.2  million  was  recorded  in  general  and  administrative
expenses for the years ended December 31, 2018, 2017 and 2016, respectively.

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Property and equipment under capital leases, included above, consists of the following at December 31, 2018 and 2017 (in thousands):

Equipment
Furniture and fixtures
Computer hardware
Computer software
Leasehold improvements

Subtotal

Less: accumulated depreciation and amortization

Property and equipment under capital leases, net

Note E – Acquisitions

2018

2017

$

$

8,430  $
1,799 
3,953 
484 
7,552 

22,218 
(10,669)

11,549  $

10,619 
1,012 
4,310 
607 
1,485 

18,033 
(7,560)

10,473 

On December  10,  2018  (“the Acquisition  Date”),  the  Company  acquired  all  of  the  issued  and  outstanding  shares  of  common  stock  of  Genesis Acquisition  Holding  Corp
(“Genesis”), and its wholly owned subsidiary, Genoptix, Inc. (“Genoptix”, and collectively with its subsidiaries and Genesis, referred to herein as "Genoptix"), for a purchase
price consisting of (i) cash consideration of approximately $127.0 million, which includes an approximately $2.0 million estimated working capital adjustment and adjustments
for estimated cash on hand of Genoptix on the Closing Date and (ii) 1.0 million shares of NeoGenomics’ common stock pursuant to the Agreement and Plan of Merger.  The
acquisition expands NeoGenomics' reach into oncology practices, and accelerates the company's progress and growth objectives.

Cartesian Medical Group, Inc. (“Cartesian”) is a California professional corporation that provided hematopathology and other pathology services to Genoptix as an independent
contractor. Cartesian is consolidated into Genoptix as a variable interest entity. Subsequent to December 31, 2018, the professional services agreement between Genoptix and
Cartesian is expected to be terminated and the Company will enter into separate Medical Services agreements with the entities owned by the physicians who were previously
employees of Cartesian. The Company does not anticipate the termination of its agreement with Cartesian having an impact on its consolidated financial statements.

The  Company  issued  approximately 1.0  million  shares  of  common  stock  as  consideration  for  the  acquisition  of  Genoptix. This  common  stock  was  issued  as  uncertificated
shares, which carries a minimum six-month holding period before they may be sold to the public. We estimated the fair value of the common stock consideration using inputs
not observable in the market and thus represents a Level 3 measurement as defined in ASC 820. The key assumption in the fair value determination was a 5 percent discount due
to lack of marketability of the common stock as a result of the restrictions imposed on the holder. The acquisition date fair value of common stock transferred is calculated
below (in thousands, except share and per share amounts):

Common Stock Valuation
Shares of common stock issued as consideration
Stock price per share on closing date
Value of common stock issued as consideration

Issue discount due to lack of marketability
Fair value of common stock at December 10, 2018

Amount

1,000,000 
13.94 

13,940 
(697)

13,243 

$

$
$

$

The following table summarizes the estimated fair values of the assets acquired and liabilities assumed at the Acquisition Date. The Company is in the process obtaining input
from third-party valuation firms of its tangible and intangible assets and other information necessary to measure the remaining assets acquired and liabilities assumed; thus, the
provisional  measurements  of  current  assets,  property  and  equipment,  intangible  assets,  goodwill,  current  liabilities,  net  deferred  tax  liabilities  and  long-term  liabilities  are
subject to change.

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The preliminary acquisition fair values below are presented as of December 10, 2018 (in thousands):

Current assets, including cash and cash equivalents of $1,381
Property and equipment
Identifiable intangible assets
Goodwill
Long-term assets

Total assets acquired
Current liabilities
Long-term liabilities (1)

Net assets acquired

$

$

22,172 
21,029 
71,792 
50,873 
170 

166,036 
(10,769)
(15,265)

140,002 

(1) Includes $14.7 million in deferred tax liabilities associated with tangible and intangible assets acquired.

Of the $71.8 million of acquired intangible assets, $56.6 million was provisionally assigned to customer relationships which are being amortized over fifteen years, $0.7 million
was provisionally assigned to the Genoptix trade name which is being amortized over one year, and $14.6 million was provisionally assigned to trade marks which are assigned
as indefinite-lived assets. We recorded approximately $0.3 million of amortization expense for the year ended December 31, 2018.

The goodwill arising from the acquisition of Genoptix includes revenue synergies as a result of our existing customers and Genoptix’ customers having access to each other’s
testing menus and capabilities and also from the new product lines which Genoptix adds to the Company’s product portfolio, including the use of COMPASS and CHART
trademarks. None  of  the  goodwill  is  expected  to  be  deductible  for  income  tax  purposes. The  provisional  fair  value  of  accounts  receivable  acquired  is  approximately $16.7
million, net of a $1.4 million fair value adjustment.

The Company recognized acquisition related transaction costs of approximately $2.3 million during the year ended December 31, 2018. These costs include due diligence, legal,
consulting  and  other  transaction  related  expenses  associated  with  the  acquisition  of  Genoptix.  These  expenses  were  included  in  general  and  administrative  expenses  in  our
consolidated statements of operations for the year ended December 31, 2018.

The amount of revenue and earnings of Genoptix since the date of acquisition that are included in the consolidated statement of operations as of December 31, 2018 are as
follows (in thousands):

Revenue
Gross Margin
Net (Loss)

For the period December 10, 2018
through December 31, 2018

$
$
$

4,629 
2,600 
(334)

The following unaudited pro forma information (in thousands) have been provided for illustrative purposes only and are not necessarily indicative of results that would have
occurred had the Acquisition been in effect since January 1, 2017, nor are they necessarily indicative of future results.

Revenue
Net income (loss) attributable to common stockholders
Income (loss) per share
Basic
Diluted

81

$

$

Years ended December 31,
(unaudited)

2018

2017 
(as adjusted)

367,988  $
1,401 

0.02  $

85,618 
91,568 

356,711 
(42,930)
(0.53)
80,426 
80,426 

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NEOGENOMICS, INC.

The  unaudited  pro  forma  consolidated  results  during  the  years  ended December  31,  2018  and 2017  have  been  prepared  by  adjusting  our  historical  results  to  include  the
Acquisition as if it occurred on January 1, 2017. These unaudited pro forma consolidated historical results were then adjusted for the following:

• Adjustments  to  reflect  amortization  expense  associated  with  the  acquired  assets,  partially  offset  by  the  elimination  of  the  amortization  and  depreciation  expense

associated with Genoptix historical assets.
Remove interest expense under the Credit Facilities as the Company has paid cash and has paid all outstanding debt balances of Genoptix.

•

As noted above, the unaudited pro forma results of operations do not purport to be indicative of the actual results that would have been achieved by the combined company for
the periods presented or that may be achieved by the combined company in the future. 

Note F – Goodwill and Intangible Assets

As a result of the acquisition of Genoptix in December of 2018, see Note E, we recorded $50.9 million in goodwill. The goodwill recorded for the year ended December 31,
2017 is primarily related to the acquisition of Clarient in 2015.

The following table summarizes the changes in goodwill for the years ended December 31, 2018 and 2017 (in thousands):

Balance, beginning of year
Goodwill acquired during the year

Balance, December 31, 2018

For the years ended December 31,

2018

2017

$

$

147,019 
50,873 

197,892 

$

$

147,019 
— 

147,019 

As a result of the acquisition of Genoptix in December of 2018, see Note E, we recorded $71.8 million in intangible assets comprised of $56.6 million in customer relationships
which are being amortized over fifteen years, $0.7 million for the Genoptix trade name which is being amortized over one year, and $14.6 million related to a trade mark with an
indefinite life which will be tested annually for impairment.

In August 2017, the Company acquired a customer list from Ascend Genomics (“Ascend”) in exchange for 450,000 shares of restricted stock, see Note P.  We recorded $4.1
million  in  intangible  assets  comprised  of  customer  relationships  which  are  being  amortized  over fifteen  years.   As  part  of  this  transaction, Ascend  signed  a  non-compete
agreement which was also recorded as an intangible asset and is being amortized over 2 years.  

As a result of the acquisition of Clarient in December 2015, we recorded $84.0 million in intangible assets comprised of $81.0 million in customer relationships amortized over
a fifteen year period and $3.0 million in trade name which we amortized over a two year period.  

The following table summarizes the allocation of goodwill by segment for the years ended December 31, 2018 and 2017 (in thousands):

Clinical Services

Pharma Services

Clinical Services

Pharma Services

2018

2018

Total 2018

2017

2017

Total 2017

Goodwill

$

178,825  $

19,067 

$

197,892 

$

127,952 

$

19,067 

$

147,019 

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Intangible assets as of December 31, 2018 and 2017 consisted of the following (in thousands): 

Amortization
Period

Cost

Trade Names
Non-Compete Agreement
Customer Relationships
Trade Mark - Indefinite lived

Total

Trade Name
Non-Compete Agreement
Customer Relationships

Total

12-24 months
24 months
180 months
— 

Amortization
Period

24 months
36 months
156-180 months

$

$

$

$

December 31, 2018

Accumulated
Amortization

$

3,675 
27 
141,626 
14,559 

$

3,042 
18 
16,798 
— 

159,887 

$

19,858 

$

Cost

$

3,000 
26 
85,068 

88,094 

$

December 31, 2017

Accumulated
Amortization

$

3,000 
4 
10,925 

13,929 

$

Net

Net

633 
9 
124,828 
14,559 

140,029 

— 
22 
74,143 

74,165 

The Company recorded amortization expense of intangible assets in the consolidated statements of operations as follows (in thousands):

Amortization of intangible assets

$

5,928  $

6,995  $

7,272 

For the Years Ended December 31,

2018

2017

2016

The Company records amortization expense as a general and administrative expense.

The estimated amortization expense related to amortizable intangible assets for each of the five succeeding fiscal years and thereafter as of December 31, 2018 is as follows (in
thousands):

Years Ending December 31,

As of December 31,

2019
2020
2021
2022
2023
Thereafter

Total

$

$

10,110 
9,442 
9,442 
9,442 
9,442 
77,592 

125,470 

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Note G – Debt

NEOGENOMICS, INC.

The following table summarizes the long term debt at December 31, 2018 and 2017 (in thousands):

Term Loan Facility
Revolving Facility
Capital leases/loans

Total Debt

Less:  Debt issuance costs
Less: Current portion of long-term debt

Total Long-Term Debt, net

2018

2017

$

$

$

96,750  $
5,000 
11,548 

113,298  $
(997)
(14,171)

98,130  $

71,250 
25,400 
10,542 

107,192 
(1,768)
(8,989)

96,435 

The  carrying  value  of  the  Company’s  long-term  capital  lease  obligations  and  term  debt  approximates  its  fair  value  based  on  the  current  market  conditions  for  similar
instruments.

Term Loan

On December 22, 2016, the Company entered into a Credit Agreement with Regions Bank as administrative agent and collateral agent.  The Credit Agreement provided for a
$75.0 million term loan facility (the “Term Loan Facility”). On June 21, 2018, the Company entered into an amendment to the Credit Agreement (the “Amendment”) which
provided for an additional term loan in the amount of $30.0 million, for which revised terms are included below. On December 31, 2018, the Company had current outstanding
borrowings under the Term Loan, as amended, of approximately $7.9 million and long-term outstanding borrowings of approximately $88.9 million, net of unamortized debt
issuance costs of $1.0 million.  These costs were recorded as a reduction in the carrying amount of the related liability and are being amortized over the life of the loan.

The Term Loan Facility bears interest at a rate per annum equal to an applicable margin plus, at NeoGenomics’ option, either (1) the Adjusted LIBOR rate for the relevant
interest period, (2) an alternate base rate determined by reference to the greatest of (a) the prime lending rate of Regions, (b) the federal funds rate for the relevant interest period
plus 0.50% per annum and (c) the one month LIBOR rate plus 1.00% per annum, or (3) a combination of (1) and (2). The applicable margin will range from 2.25% to 4.00% for
LIBOR loans and 1.25% to 3.00% for base rate loans, in each case based on NeoGenomics’ consolidated leverage ratio (as defined in the Credit Agreement and revised in the
Amendment).  Interest  on  borrowings  is  payable  on  the  last  day  of  each  month,  in  the  case  of  each  base  rate  loan,  and  on  the  last  day  of  each  interest  period  (but  no  less
frequently than every three months), in the case of Adjusted LIBOR loans.  The Company entered into interest rate swap agreements to hedge against changes in the variable
rate of a portion of both the Term Loan Facility and the Amendment.  See Note H -Derivative Instruments and Hedging Activities for more information on these instruments.

The Term Loan Facility and amounts borrowed under the Revolving Facility are secured on a first priority basis by a security interest in substantially all of the tangible and
intangible  assets  of  NeoGenomics  and  the  Guarantors.    The  Term  Loan  Facility  contains  various  affirmative  and  negative  covenants  including  ability  to  incur  liens  and
encumbrances; make certain restricted payments, including paying dividends on its equity securities or payments to redeem, repurchase or retire its equity securities; enter into
certain  restrictive  agreements;  make  investments,  loans  and  acquisitions;  merge  or  consolidate  with  any  other  person;  dispose  of  assets;  enter  into  sale  and  leaseback
transactions; engage in transactions with its affiliates, and materially alter the business it conducts.  In addition, the Company must meet certain maximum leverage ratios and
fixed  charge  coverage  ratios  as  of  the  end  of  each  fiscal  quarter  commencing  with  the  quarter  ending  March  31,  2017.    The  Company  was  in  compliance  with  all  required
financial covenants as of December 31, 2018.

The Term Loan Facility, as amended, has a maturity date of December 21, 2021.  The Credit Agreement requires NeoGenomics to mandatorily prepay the Term Loan Facility
and amounts borrowed under the Revolving Facility with (i) 100% of net cash proceeds from certain sales and dispositions, subject to certain reinvestment rights, (ii) 100% of
net cash proceeds from certain issuances or incurrences of additional debt, (iii) beginning with the fiscal year ending December 31, 2018, 75% of consolidated excess cash flow
(as defined) if NeoGenomics' consolidated leverage ratio is greater than or equal to 3.25:1.0 or 50% of consolidated excess cash flow (as defined) if NeoGenomics' consolidated
leverage  ratio  is  less  than  or  equal  to 3.25:1.0  but  greater  than  or  equal  to 2.75:1.0  and  (iv) 100%  of  net  cash  proceeds  from  issuances  of  permitted  equity  securities  by
NeoGenomics made in order to cure a failure to comply with the financial covenants. NeoGenomics is permitted to voluntarily prepay the Term Loan Facility and amounts
borrowed under the Revolving Facility at any time without penalty. 

Revolving Facility

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On December 22, 2016, the Company entered into a Credit Agreement with Regions Bank as administrative agent and collateral agent.  The Credit Agreement provided for a
$75 million revolving credit facility (the “Revolving Facility”).  On December 31, 2018, the Company had total outstanding borrowings of approximately $5.0 million,  with
unamortized debt issuance costs of $0.8 million. These costs were recorded in other assets and are being amortized over the life of the loan.

The  Revolving  Facility  includes  a $10 million  swingline  sublimit,  with  swingline  loans  bearing  interest  at  the  alternate  base  rate  plus  the  applicable  margin. Any  principal
outstanding under the Revolving Facility is due and payable on December 21, 2021 or such earlier date as the obligations under the Credit Agreement become due and payable
pursuant to the terms of the Credit Agreement.  The Revolving Facility bears interest at a rate per annum equal to an applicable margin plus, at NeoGenomics’ option, either (1)
the Adjusted  LIBOR  rate  for  the  relevant  interest  period,  (2)  an  alternate  base  rate  determined  by  reference  to  the  greatest  of  (a)  the  prime  lending  rate  of  Regions,  (b)  the
federal funds rate for the relevant interest period plus 0.50% per annum and (c) the one month LIBOR rate plus 1.00% per annum, or (3) a combination of (1) and (2). The
applicable  margin  will  range  from 2.25%  to 4.00%  for Adjusted  LIBOR  loans  and 1.25%  to 3.00%  for  base  rate  loans,  in  each  case  based  on  NeoGenomics’  consolidated
leverage ratio. Interest on the outstanding principal of the Term Loan Facility will be payable on the last day of each month, in the case of each base rate loan, and on the last
day of each interest period (but no less frequently than every three months), in the case of LIBOR loans. The Company was in compliance with all required financial covenants
as of December 31, 2018.

The Credit Agreement, as amended, requires NeoGenomics to mandatorily prepay the Term Loan Facility and amounts borrowed under the Revolving Facility with (i) 100% of
net cash proceeds from certain sales and dispositions, subject to certain reinvestment rights, (ii) 100% of net cash proceeds from certain issuances or incurrences of additional
debt, (iii) beginning with the fiscal year ending December 31, 2018, 75% of excess cash flow (as defined) if NeoGenomics' consolidated leverage ratio is greater than or equal to
3.25:1.0 or 50% of consolidated excess cash flow (as defined) if NeoGenomics' consolidated leverage ratio is less than or equal to 3.25:1.0 but greater than or equal to 2.75:1.0
and (iv) 100% of net cash proceeds from issuances of permitted equity securities by NeoGenomics made in order to cure a failure to comply with the financial covenants. For the
year ended December 31, 2018, no excess cash flow payment was due.  NeoGenomics is permitted to voluntarily prepay the Term Loan Facility and amounts borrowed under
the Revolving Facility at any time without penalty, subject to customary “breakage” costs with respect to prepayments of Adjusted LIBOR rate loans made on a day other than
the last day of any applicable interest period.

Capital Leases

The Company has entered into capital leases to purchase laboratory and office equipment.  These leases expire at various dates through 2021 and the weighted average interest
rate under such leases was approximately 4.56% at December 31, 2018. Most of these leases contain bargain purchase options that allow us to purchase the leased property for a
minimal amount upon the expiration of the lease term. The remaining leases have purchase options at fair market value.      

Property and equipment acquired under capital lease agreements (see Note D) are pledged as collateral to secure the performance of the future minimum lease payments.

Maturities of Long-Term Debt

Maturities of long-term debt at December 31, 2018 are summarized as follows (in thousands):

2019
2020
2021

Less:  Interest on capital leases

Less: Current portion of long-term debt
Less:  Debt issuance costs

Long-term debt, net

Debt

Capital Lease Obligations &
Car Loans

Total Long Term Debt

7,873  $
7,873 
86,004 

101,750  $

— 

101,750 
(7,873)
(997)

92,880  $

6,706  $
4,241 
1,202 

12,149  $
(601)

11,548 
(6,298)
— 

5,250  $

14,579 
12,114 
87,206 

113,899 
(601)

113,298 
(14,171)
(997)

98,130 

$

$

$

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NEOGENOMICS, INC.

Note H – Derivative Instruments and Hedging Activities

Cash Flow Hedges

In December of 2016 and June of 2018, the Company entered into interest rate swap agreements to reduce our exposure to interest rate fluctuations on our variable rate debt
obligations.    These  derivative  financial  instruments  are  accounted  for  at  fair  value  as  a  cash  flow  hedge which  effectively  modifies  our  exposure  to  interest  rate  risk  by
converting a portion of our floating rate debt to a fixed rate obligation, thus reducing the impact of interest rate changes on future interest expense.

We  account  for  derivatives  in  accordance  with ASC  Topic  815.  See  Note  B  for  more  information  on  our  accounting  policy  related  to  derivative  instruments  and  hedging
activities.  The fair value measurements of the Company's interest rate swaps are classified within Level 2 of the fair value hierarchy

Under  these  agreements,  we  receive  a  variable  rate  of  interest  based  on  LIBOR  and  we  pay  a  fixed  rate  of  interest.  The  following  table  summarizes  the  interest  rate  swap
agreements.

Notional Amount
Effective Date
Index
Maturity
Rate

December 2016 Hedge

June 2018 Hedge

$50 million
December 30, 2016
One month LIBOR
December 31, 2019
1.59  %

$20 million (1)
June 29, 2018
One month LIBOR
December 31, 2021
2.98  %

(1) The notional amount increases to $70 million upon maturity of December 2016 Hedge on December 31, 2019.

The fair value of the interest rate swap will be included in long-term assets or long-term liabilities, when applicable. At December 31, 2018, we recorded the fair value of these
derivative financial instruments of which $0.5 million was included as an other long-term asset and $0.9 million was included as a long-term liability. These amounts were also
reflected in AOCI.  At  December 31, 2017, the fair value of the derivative financial instruments was $0.4 million, which was included in the balance sheet as other assets and
reflected in AOCI.  The instruments will be evaluated on a monthly basis and resulting increases or decreases will be recorded as a component of AOCI and will be reclassified
to interest expense in the period during which the hedged transaction affects earnings.  Any cash flows from the interest rate swap are included in operating activities on the
consolidated statement of cash flows. The Company performed an effectiveness assessment and determined that the interest rate swaps are highly effective and, thus, there is no
impact to the Company's consolidated statements of operations. As of December 31, 2018, the Company estimates that any amounts reclassified from AOCI to earnings during
the next twelve months will be immaterial.   

Note I – Class A Redeemable Convertible Preferred Stock

On December 30, 2015, (“Original Issue Date”), the Company issued 14,666,667 shares of its Series A Redeemable Convertible Preferred stock (“Series A Preferred Stock”)
as part of the consideration given to acquire all of the outstanding stock of Clarient Inc.  The Series A Preferred Stock has a face value of  $7.50 per share for a total liquidation
value of $110.0 million.  

During the first year, the Series A Preferred Stock had a liquidation value of $100.0 million if the shares were redeemed prior to December 29, 2016. On December 22, 2016,
the Company redeemed 8,066,667 shares of the Series A Preferred Stock for $55.0 million in cash. The redemption amount per share equaled $6.82 ($7.50 minus the liquidation
discount  of 9.09%) . In  December  2017,  the  Company  issued 264,000  additional  shares  of  Preferred  Stock  as  a  Paid-in-Kind  (“PIK”)  dividend,  resulting  in  a  balance  of
6,864,000 shares of Series A Preferred Stock outstanding at December 31, 2017.

On  June  25,  2018,  the  Company  redeemed  the  remaining  outstanding  Preferred  Stock  for  an  aggregate  redemption  amount  of $50.1 million,  prior  to  consideration  of  any
transaction related expenses. The shares were redeemed at $7.30 per share, representing the applicable 4.55% redemption discount on the original liquidation preference plus an
additional $0.14 per share in respect of accrued and unpaid dividends for 2018. Following the redemption, no shares of Preferred Stock remain outstanding.

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The gain on redemption of preferred stock was calculated as the carrying value of the shares of Preferred Stock before the redemption of $37.8 million plus the amount of the
beneficial conversion feature originally recorded with the redeemed shares of $21.3 million, as compared to the total consideration being paid, in this case the $50.1 million.

 Issue Discount

The Company recorded the Series A Preferred Stock at a fair value of approximately $73.2 million, or $4.99 per share, on the date of issuance. The difference between the fair
value of $73.2 million and the liquidation value of $110 million represents a discount of $36.8 million from the initial face value representing the impact the rights and features
of the instrument had on the value to the Company. After the partial redemption, the Series A Preferred stock had a fair value of approximately $32.9 million, or $4.99 per share.
The difference between the fair value of $32.9 million and the liquidation value of $49.5 million represented a discount of approximately $16.6 million.

Beneficial Conversion Features

The fair value of the common stock into which the Series A Preferred Stock was convertible exceeded the allocated purchase price fair value of the Series A Preferred Stock at
the date of issuance and after the partial redemption in December of 2016 by approximately $44.7 and $20.1 million, respectively, resulting in a beneficial conversion feature.
The  Company  recognized  the  beneficial  conversion  feature  as  non-cash,  deemed  dividends  to  the  holder  of  Series A  Preferred  Stock  over  the  first  three  years  the  Series A
Preferred Stock was outstanding, as the date the stock first becomes convertible was three years from the issue date. In addition to the beneficial conversion feature (“BCF”)
recorded at the original issue date, we recorded additional BCF discounts for payment-in-kind shares accrued for the quarter ended March 31, 2018 as dividends.

 Automatic Conversion

Absent  an  early  redemption,  each  share  of  Series A  Preferred  Stock  issued  and  outstanding  as  of  the  tenth  anniversary  of  the  original  issue  date  would  have  automatically
converted into fully paid and non-assessable shares of common stock.

Classification

Prior to redemption, the Company classified the Preferred Stock as temporary equity on the consolidated balance sheets due to certain change in control events that are outside
the Company’s control, including deemed liquidation events described in the Series A Certificate of Designation.

Note J – Income Taxes

On December 22, 2017, the United States enacted the Tax Cuts and Jobs Act.  The Act made significant modifications to the provisions of the Internal Revenue Code, including
but not limited to, a corporate tax rate decrease from 35% to 21% effective as of January 1, 2018.  The Company’s net deferred tax assets and liabilities have been revalued at
the  newly  enacted  U.S.  corporate  rate  in  the  year  of  enactment.    The  adjustment  related  to  the  remeasurement  of  the  deferred  tax  asset  and  liability  balances,  including  the
revaluation of amounts originally reported in other comprehensive income (loss), is a net benefit of $3.0 million and is included in income as of December 31, 2017.  

Significant components of the provision for income taxes for the years ended December 31, 2018, 2017 and 2016 are as follows (in thousands):

Current:

Federal
State

Total Current Provision (Benefit)

Deferred:
Federal
State
Foreign

Total Deferred Provision (Benefit)

Total Tax Provision

2018

2017 
(as adjusted)

2016 
(as adjusted)

$

$

$

$

$

(448) $
126 

(322) $

1,070  $
321 
115 

1,506  $

1,184  $

(91) $
14 

(77) $

(2,359) $
297 
(115)

(2,177) $

(2,254) $

(8)
39 

31 

(1,451)
(281)
— 

(1,732)

(1,701)

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A reconciliation of the differences between the effective tax rate and the federal statutory tax rate for the years ended December 31, 2018, 2017 and 2016 is as follows:

Federal statutory tax rate
State income taxes, net of federal income tax benefit
Non-deductible expenses
Compensation expense
Transaction expenses
Deferred revaluation for Tax Cuts and Jobs Act
Adjustment due to adoption of Accounting Standards
Foreign Tax Rate Differential
Other, net
Valuation allowance

Effective tax rate

2018

2017 
(as adjusted)

2016

21.00  %
11.01  %
3.80 %
(12.52)%
7.09 %
— %
(13.84)%
7.20 %
(1.21)%
8.44 %

30.97  %

34.00  %
(4.96)%
(17.57)%
(25.95)%
— %
116.24 %
— %
(12.99)%
(3.72)%
— %

85.05  %

34.00  %
3.43 %
(1.88)%
(13.37)%
— %
— %
— %
— %
0.73 %
— %

22.91  %

At December 31, 2018 and 2017, our current and non-current deferred income tax assets and liabilities consisted of the following (in thousands):

Net non-current deferred income tax liability:

Allowance for doubtful accounts
Accrued compensation
Other accruals
Other
Net operating loss carry-forwards
Nonqualified stock options and warrants
Accumulated depreciation and amortization

Net deferred income tax liabilities
Less: Valuation allowance

Total Non-Current Deferred Income Tax Liability

2018

2017 
(as adjusted)

634  $

1,935 
156 
502 
17,825 
1,613 
(44,799)

(22,134)
(323)

(22,457) $

170 
943 
84 
(274)
12,282 
1,342 
(21,235)

(6,688)
— 

(6,688)

$

$

At December 31, 2018, the Company has federal net operating loss carry forwards of approximately $71.3 million and state net operating loss carry forwards of approximately
$33.0  million.  The  Company  adopted  ASU  2016-09  as  of  January  1,  2017.    Adoption  required  a  modified  retrospective  transition  whereby  the  cumulative-effect  is  an
adjustment to equity as of the beginning of the period.  This resulted in an adjustment to the deferred tax assets related to net operating loss carryforwards and equity of $6.4
million.  These net operating loss carry forwards will begin to expire in 2030, for both federal and state tax purposes, if not utilized in future periods. An ownership change of
more than 50 percent could result in a limitation of the use of net operating loss carryforwards under IRC Section 382 and the regulations thereunder. Management believes it is
more likely than not that a limitation under Section 382 would not impact the realizability of the federal and state net operating loss deferred tax assets.

Management assesses the recoverability of its deferred tax assets as of the end of each quarter, weighing all positive and negative evidence, and is required to establish and
maintain a valuation allowance for these assets if it's determined that it is more likely than not that some or all of the deferred tax assets will not be realized. The weight given
to  the  evidence  is  commensurate  with  the  extent  to  which  the  evidence  can  be  objectively  verified.  If  negative  evidence  exists,  positive  evidence  is  necessary  to  support  a
conclusion that a valuation allowance is not needed. As of December 31, 2018, management determined that sufficient positive evidence did not exist to conclude that it is more
likely  than  not  that  the  Net  Operating  Losses  being  generated  by  the  Company's  Switzerland  and  Singapore  operations  would  be  able  to  be  utilized  in  future  periods.
Accordingly, management has decided to establish a full valuation allowance of $0.3 million against the deferred tax assets generated by these two jurisdictions.

We file income tax returns in the U.S. federal jurisdiction as well as Singapore, Switzerland and in various state jurisdictions. Tax regulations within each jurisdiction are subject
to the interpretation of the related tax laws and regulations and require significant judgment. For federal and state purposes, we have open tax years ending December 31, 2010
to December 31, 2017.  We are not currently subject to any ongoing income tax examinations.

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The Company adopted the accounting standard for uncertain tax positions, ASC 740-10, and as required by the standard, the Company recognizes the financial statement benefit
of a tax position only after determining that the relevant tax authority would more likely than not sustain the position following an audit. For tax positions meeting the more
likely than not threshold, the amount recognized in the financial statements is the largest benefit that has a greater than 50 percent likelihood of being realized upon ultimate
settlement  with  the  relevant  tax  authority.  Increases  or  decreases  to  the  unrecognized  tax  benefits  could  result  from  management’s  belief  that  a  position  can  or  cannot  be
sustained upon examination based on subsequent information or potential lapse of the applicable statute of limitation for certain tax positions.

The following is our unrecognized tax benefits as of December 31, 2018 (in thousands):

Unrecognized tax benefits - December 31, 2017
Increases from acquisitions
Settled positions
Statute expirations

Unrecognized tax benefits - December 31, 2018

Year Ended December 31, 

2018

— 
632 
— 
— 

632 

$

$

The  amount  of  unrecognized  tax  benefits  at December 31, 2018,  if  recognized  would  favorably  affect  the  Company's  effective  tax  rate. These  unrecognized  tax  benefits  are
classified as other long term liabilities in the Company's consolidated balance sheet. The interest and penalties related to the unrecognized tax benefit are $0.1  million. Interest
and tax penalties related to unrecognized tax benefits are included in income tax expense. There were no uncertain tax positions for the years ended December 31, 2017 or 2016.

The Company has received a temporary tax holiday in Switzerland as an incentive to locate and grow our operations. The tax holiday is for two consecutive 5  year  periods
beginning with the year ended December 31, 2017 and is dependent on meeting agreed upon employment and capital investment targets. The first 5 year period ends with the
year ended December 31, 2021 fiscal year and the second 5 year period, should our employment and capital investment targets be met end with the 2026 fiscal year.  As the
Switzerland operations have been in a tax loss position since inception, no financial benefits have been realized in 2017 or 2018 under the tax holiday.

Note K – Net Income (Loss) per Share

The following table provides the  computation  of  basic  and  diluted  net  income  (loss)  per  share  for  the  years  ended December 31, 2018, 2017  and 2016  (in  thousands,  except
share and per share amounts):

Net income (loss)
Deemed dividends on preferred stock
Gain on redemption of preferred stock
Amortization of preferred stock beneficial conversion feature

Net income (loss) available to common stockholders

Basic weighted average common shares outstanding
Effect of potentially dilutive securities

Diluted weighted average shares outstanding

Basic net income (loss) per share attributable to common stockholders

Diluted net income (loss) per share attributable to common stockholders

Year Ended December 31,

2018

2017 
(as adjusted)

2016 
(as adjusted)

$

$

$

$

2,640  $
10,198 
(9,075)
(4,571)

6,088  $

85,618 
5,950 

91,568 

0.07  $

0.07  $

(396) $
3,645 
— 
6,902 

(10,943) $

79,426 
— 

79,426 

(0.14) $

(0.14) $

(6,142)
18,011 
— 
6,663 

(30,816)

77,542 
— 

77,542 

(0.40)

(0.40)

We have adopted the two-class method in calculating earnings per share as we have determined our preferred shares to be participating securities.  Under this method, we have
included in weighted average shares outstanding all of our preferred shares

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as we have assumed conversion to common shares.  In periods of net loss, we have not allocated the net loss to our participating shareholders as they do not have a contractual
obligation to share in losses.

For the years ended December 31, 2018, 2017 and 2016, 0.3, 1.6 and 1.7 million options were excluded from the calculation of diluted earnings per share because the effect of
including  these  potential  shares  was  anti-dilutive.  For  periods  in  which  the  impact  of  contingently  convertible  Series A  Preferred  Stock  was  anti-dilutive,  these  shares  were
excluded from the calculation of diluted earnings per share. 

Note L – Stock Compensation

Stock Option Plan

On  May  25,  2017,  the  board  of  directors  of  Parent  (the  “Board  of  Directors”)  further  amended  the  Equity  Incentive  Plan,  originally  effective  as  of  October  14,  2003,  and
previously amended and restated effective as of October 31, 2006, April 16, 2013, May 4, 2015 and December 21, 2015. The Amended Plan allows for the award of equity
incentives,  including  stock  options,  stock  appreciation  rights,  restricted  stock  awards,  stock  bonus  awards,  deferred  stock  awards,  and  other  stock-based  awards  to  certain
employees,  directors,  or  officers  of,  or  key  non-employee  advisers  or  consultants,  including  contracted  physicians  to  the  Company  or  its  subsidiaries.  The Amended  Plan,
provides that the maximum aggregate number of shares of the Company’s common stock reserved and available for issuance under the Amended Plan is 18,650,000.

As  of December  31,  2018  and 2017,  stock  options  outstanding  totaled 6.8 million  and 6.3  million  shares,  respectively.    The  outstanding  options  in 2017  included 200,000
options  issued  outside  of  the Amended  Plan  to  Douglas  VanOort,  the  Company’s  Chairman  and  Chief  Executive  Officer.   As  of  December  31,  2018  and 2017,  a  total  of
approximately 3.3 million and 5.4 million shares, respectively, were available for future option and stock awards under the Amended Plan. Options typically expire after 5 years
and generally vest over 3 or 4 years, but each grant’s expiration, vesting and exercise price provisions are determined at the time the awards are granted by the Compensation
Committee of the Board of Directors.

The fair value of each stock option award granted during the years ended December 31, 2018, 2017 and 2016 was estimated as of the grant date using a trinomial lattice model
with the following weighted average assumptions:

Expected term (in years)
Risk-free interest rate (%)
Expected volatility (%)
Dividend yield (%)
Weighted average fair value/share at grant date

2018

2017

2016

1.6 – 4.0
2.5  %
43.0  %
0.0  %

3.0 – 4.5
1.5  %
49.0  %
0.0  %

$

2.80  $

2.26  $

1.0 – 4.5
1.1  %
54.0  %
0.0  %
2.23 

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The status of our stock options are summarized as follows: 

Outstanding at Outstanding at December 31, 2015
Granted
Exercised
Forfeited

Outstanding at Outstanding at December 31, 2016
Granted
Exercised
Forfeited

Outstanding at Outstanding at December 31, 2017
Granted
Exercised
Forfeited

Outstanding at Outstanding at December 31, 2018

Exercisable at Exercisable at December 31, 2018

Number
Of
Shares

Weighted
Average
Exercise
Price

5,326,505  $
2,617,526 
(2,483,519)
(324,402)

5,136,110 
2,119,498 
(565,569)
(347,513)

6,342,526 
2,457,102 
(1,570,211)
(390,000)

6,839,417 

2,508,890 

3.07 
7.14 
1.69 
3.99 

5.76 
7.60 
3.84 
6.12 

6.51 
9.03 
5.48 
7.15 

7.63 

6.42 

The number and weighted average grant-date fair values of options non-vested at the beginning and end of 2018, as well as options granted, vested and forfeited during the year
was as follows:

Non-vested at Non-vested at December 31, 2017
Granted in Granted
Vested in Vested
Forfeited in Forfeited

Non-vested at Non-vested at December 31, 2018

The following table summarizes information about our options outstanding at December 31, 2018:

Number of
Options

Weighted
Average
Grant Date
Fair Value

4,239,185  $
2,457,102 
(2,039,176)
(326,585)

4,330,526 

2.29 
2.80 
2.69 
2.97 

2.67 

Range of
Exercise
Prices ($)
3.31 – 6.00
6.01 – 7.00
7.01 – 8.00
8.01 – 9.00
9.01 – 14.40

Options Outstanding

Options Exercisable

Number
Outstanding

869,667 
289,166 
2,924,201 
1,949,670 
806,713 

6,839,417 

Weighted
Average
Remaining
Contractual
Life (Years)

Weighted
Average
Exercise
Price

1.20 $
2.07
2.85
4.01
4.45

3.12

4.68 
6.76 
7.35 
8.04 
11.10 

7.63 

Number
Exercisable

858,000 
151,671 
1,348,004 
114,996 
36,219 

2,508,890 

Weighted
Average
Remaining
Contractual
Life (Years)

Weighted
Average
Exercise
Price

1.19 $
2.05
2.67
2.83
3.31

2.43

4.66 
6.75 
7.30 
7.93 
9.12 

6.42 

As of December 31, 2018, the aggregate intrinsic value of all stock options outstanding and expected to vest was approximately $34.4 million and the aggregate intrinsic value
of currently exercisable stock options was approximately $15.5 million. The intrinsic value of each option share is the difference between the fair market value of NeoGenomics'
common stock and the exercise price of such option share to the extent it is “in-the-money”. Aggregate intrinsic value represents the value that would have been received by the
holders of in-the-money options had they exercised their options on the last trading day of the year and sold the underlying shares at the closing stock price on such day. The
intrinsic value calculation is based on the $12.61

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closing stock price of NeoGenomics Common Stock on December 31, 2018, the last trading day of 2018. The total number of in-the-money options outstanding and exercisable
as of December 31, 2018 was approximately 2.5 million.

The  total  intrinsic  value  of  options  exercised  during  the  years  ended December  31,  2018, 2017  and 2016  was  approximately $29.3 million,  $2.8  million  and $15.0  million,
respectively. Intrinsic value of exercised shares is the total value of such shares on the date of exercise less the cash received from the option holder to exercise the options. The
total cash proceeds received from the exercise of stock options was approximately $8.6 million, $2.2 million and $4.2 million for the years ended December 31, 2018, 2017 and
2016, respectively.

The total fair value of options granted during the years ended December 31, 2018, 2017 and 2016 was approximately $6.9 million, $4.8 million  and $6.5 million, respectively.
The total fair value of option shares vested during the years ended December 31, 2018, 2017 and 2016 was approximately $5.5 million, $3.6 million and $2.2 million.

We recognize stock-based compensation expense using the straight-line basis over the awards’ requisite service periods.  Stock compensation expense related to stock options
for  the  years  ended December  31,  2018, 2017  and 2016  was  approximately $5.4 million, $5.0 million  and $5.0  million,  respectively.  As  of December  31,  2018,  there  was
approximately $5.1 million of total unrecognized stock-based compensation cost related to unvested stock options granted under the Amended Plan. This cost is expected to be
recognized over a weighted-average period of 2.1 years.

Employee Stock Purchase Plan

The Company sponsors an Employee Stock Purchase Plan (“ESPP”), under which eligible employees can purchase common stock at a discount from the fair market value.  In
accordance with ASC Topic 718-50, Compensation – Stock Compensation – Employee Share Purchase Plans, the ESPP was considered non-compensatory and did not require
the recognition of compensation cost because the discount offered to employees did not exceed 5%.

On May 25, 2017, the Company amended the ESPP, increasing the discount from 5% to 15%.  As a result of this change, we recognized stock-based compensation expense for
the  year  ended December 31, 2018  and 2017  in  the  amount  of  approximately $0.2 million  and $0.1 million,  respectively.    Shares  issued  pursuant  to  this  plan  were 113,503,
108,599 and 98,672 for the years ended December 31, 2018, 2017 and 2016, respectively.

Common Stock Warrants

From time to time, the Company issues warrants to purchase its common stock. These warrants have been issued for consulting services, in connection with the Company’s
credit facilities and sales of its common stock and in connection with employment agreements and for compensation to directors. These warrants are valued using trinomial
lattice pricing model and using the volatility, market price, strike price, risk-free interest rate and dividend yield appropriate at the date the warrants were issued.    There were
no warrants outstanding as of December 31, 2017 and no warrant activity for the year ended December 31, 2018.

Warrant activity is summarized as follows:

Shares

Weighted Average 
Exercise Price

Warrants outstanding, December 31, 2015

Granted
Exercised
Expired/Cancelled
Warrants outstanding, December 31, 2016

Granted
Exercised
Expired/Cancelled
Warrants outstanding, December 31, 2017

$

650,000 
— 
(200,000)
— 

450,000 
— 
(450,000)
— 

— 

1.48 
— 
— 
— 

1.50
— 
1.50 
— 

— 

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Restricted Stock Awards

The  number  and  weighted  average  grant  date  fair  values  of  restricted  non-vested  common  stock  at  the  beginning  and  end  of 2018, 2017  and 2016,  as  well  as  stock  awards
granted, vested and forfeited during the year are as follows:

Nonvested at Nonvested at December 31, 2015
Granted in Granted in 2016
Vested in Vested in 2016
Forfeited in Forfeited in 2016

Nonvested at Nonvested at December 31, 2016
Granted in Granted in 2017
Vested in Vested in 2017
Forfeited in Forfeited in 2017

Nonvested at Nonvested at December 31, 2017
Granted in Granted in 2018
Vested in Vested in 2018
Forfeited in Forfeited in 2018

Nonvested at Nonvested at December 31, 2018

Number
of
Restricted
Shares

Weighted
Average
Grant Date
Fair Value

126,995  $
43,332 
(33,083)
— 

137,244 
372,711 
(182,744)
— 

327,211 
87,811 
(119,180)
(13,334)

282,508 

3.10 
8.49 
8.13 
— 

3.59 
7.27 
4.50 
— 

7.27 
12.87 
7.27 
7.27 

9.01 

Stock compensation expense related to restricted stock for the years ended December 31, 2018, 2017 and 2016 was approximately $1.3 million, $1.3 million,  and $0.5 million,
respectively.

Note M – Commitments and Contingencies

Operating Leases

The  Company  leases  approximately 250,000 square feet of office and laboratory space under non-cancelable operating leases. These operating leases expire at various dates
through 2023. These leases generally require the payment of real estate taxes, insurance, maintenance, utility and operating costs.

The following is a schedule of future minimum obligations under non-cancelable operating leases as of December 31, 2018 (in thousands):

Years ending December 31,

2019
2020
2021
2022
2023
Thereafter

Total minimum lease payments

$

$

5,247 
2,798 
1,082 
453 
92 
— 

9,672 

Rent expense for the years ended December 31, 2018, 2017  and 2016  was  approximately $4.1 million, $4.7 million  and $4.2 million, respectively and is included in costs of
revenues and in general and administrative expenses, depending on the allocation of work space in each facility. Certain of the Company’s facility leases include rent escalation
clauses. The Company normalizes rent expense on a straight-line basis for known changes in lease payments over the life of the lease.

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Purchase Commitments

The Company has agreements in place to purchase a specified level of reagents from certain vendors. These purchase commitments expire at various dates through 2020. The
purchase commitments as of December 31, 2018 are as follows (in thousands):

Years ending December 31,

2019
2020
2021

Total purchase commitments

Capital Lease Obligations

$

$

220 
220 
110 

550 

The Company’s capital lease obligations expire at various times through 2021 and the weighted average interest rates under such leases approximated 4.56%  at December 31,
2018.  Some  of  our  leases  contain  bargain  purchase  options  that  allow  us  to  purchase  the  leased  property  for  a  minimal  amount  upon  the  expiration  of  the  lease  term.  The
remaining leases have purchase options at fair market value. See Note G for more information about future minimum lease payments under capital lease obligations, including
those described above.  Property and equipment acquired under capital lease agreements (see Note D) are pledged as collateral to secure the performance of the future minimum
lease payments shown in Note G.

Employment Contracts

The  agreements  with  our  Chief  Executive  Officer,  Chief  Financial  Officer,  President  of  Pharma  Services,  President  of  Clinical  Services,  and  Chief  Strategy  and  Corporate
Development Officer & Director of Investor Relations
contain some or all of the following:

•

•

Clauses that allow for continuous automatic extensions of one year unless timely written notice terminating the contract is provided to such officers (as defined
in the agreements).
Clauses that provide for 6-12 months of severance benefits in the event that such officers are terminated without “cause” (as defined in the agreements) by the
Company. The base salaries for these officers in 2018 approximates $2.1 million.

Note N – Related Party Transactions

On May 3, 2010, the Company entered into a consulting agreement with Steven C. Jones, a director, officer and shareholder of the Company whereby Mr. Jones would provide
consulting services to the Company in the capacity of Executive Vice President. On May 3, 2010, the Company also entered into a warrant agreement with Mr. Jones and issued
a warrant to purchase 450,000 shares of the Company’s common stock, which were all vested as of December 31, 2016 and fully exercised at December 31, 2017.

On November 4, 2016, the Company entered into an amended and restated consulting agreement (the “Amended and Restated Consulting Agreement”) with Mr. Jones.  The
Amended and Restated Consulting Agreement has an initial term of November 4, 2016 through April 30, 2020, which automatically renews for additional one year periods
unless either party provides notice of termination at least three months prior to the expiration of the initial term or any renewal term. In addition, the Company has the right to
terminate the Amended and Restated Consulting Agreement by giving written notice to Mr. Jones the year prior to the effective date of termination. Mr. Jones has the right to
terminate the Amended and Restated Consulting Agreement by giving written notice to the Company three months prior to the proposed termination date, provided, however,
Mr.  Jones  is  required  to  provide  an  additional  three  months  of  transition  services  to  the  Company  upon  reasonable  request  by  the  Company.  The Amended  and  Restated
Consulting Agreement specifies monthly base retainer compensation of $21,666  per  month  until April  30,  2017; $15,000 per month from May 1, 2017 until April 30, 2018;
$12,500 per month from May 1, 2018 until April 30, 2019; and $10,000 per month thereafter. Mr. Jones is also eligible to receive a cash bonus based on the achievement of
certain performance metrics with a target of 35% of his base retainer for any given fiscal year. Such bonus is eligible to be increased to up to 150% of the target bonus in any
fiscal year in which he meets certain performance thresholds established by the CEO of the Company and approved by the Board of Directors.

During  the  years  ended December  31,  2018, 2017  and 2016,  Mr.  Jones  earned  approximately $163,000,  $242,000  and $263,000,  respectively,  for  various  consulting  work
performed  in  connection  with  his  duties  as  an  Executive  Vice  President  and  reimbursement  of  incurred  expenses.    Mr.  Jones  also  earned  $58,013, $31,912  and $85,000  as
payment of bonuses for the periods indicated above.  During the years ended December 31, 2018, 2017  and 2016, Mr. Jones earned approximately $50,000, $50,000,  and $0,
respectively as compensation for his services on the Board.

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The following table summarizes stock options and restricted stock granted to Mr. Jones during the years ended December 31, 2018, 2017 and 2016:

Grant Date

Common Stock Shares
Granted

Restricted Common Stock
Shares Granted

Fair Value

Fair Value per Share

Grant Price

June 1, 2018
June 1, 2018
May 25, 2017
May 25, 2017
April 20, 2016

3,017 
— 
10,000 
— 
100,000 

—  $
6,897  $
—  $
8,667  $
—  $

11,284  $
80,005  $
24,700  $
63,009  $
250,000  $

3.74  $
11.60  $
2.47  $
7.27  $
2.50  $

11.60 
— 
7.27 
— 
7.15 

Note O – Retirement Plan

We  maintain  a  defined-contribution  401(k)  retirement  plan  covering  substantially  all  employees  (as  defined).  Our  employees  may  make  voluntary  contributions  to  the  plan,
subject to limitations based on IRS regulations and compensation. In addition, we match any employees’ contributions at the rate of  75% of every dollar contributed up to 4% of
the  respective  employee’s  salary  (3%  maximum  Company  match).  Effective,  January  1,  2017  this  benefit  increased  to 100%  of  every  dollar  contributed  up  to 3%  of  the
respective employee’s compensation and an additional 50% of every dollar contributed on the next 2% of compensation (4% maximum Company match).  We made matching
contributions of approximately $2.7 million, $2.5 million and $1.7 million during the years ended December 31, 2018, 2017 and 2016, respectively.  

Note P – Equity Transactions

Public Offering of Common Stock

The Company completed an offering of approximately 11.3 million shares of registered common stock, at a price of $12.75 per share, for gross proceeds of $143.7 million. The
Company received $135.1 million in net proceeds after deducting underwriting fees of $8.6 million.

Common Stock Issued for Transactions/Acquisitions

As discussed in Note E, The Company issued 1.0 million shares of restricted common stock as consideration for the acquisition of Genoptix in December of 2018.

As  discussed  in  Note  F,  the  Company  issued  approximately 0.5  million  shares  of  restricted  common  stock  as  consideration  for  the  purchase  of  a  customer  list  in August
2017.  The restriction prohibits Ascend from registering and trading the shares for a period of six months from the issuance date.

On  December  30,  2015,  the  Company  issued 15.0 million shares of common  stock  as  consideration  for  the  acquisition  of  Clarient.    The  common  stock  includes  restrictions
imposed on the holder in the Investor Board Rights, Lockup and Standstill Agreement. 

Preferred Stock Issued to GE Medical

On December 30, 2015 the Company issued 14.7 million shares of Series A Preferred Stock as consideration for the acquisition of Clarient.  In 2016, the Company redeemed
approximately 8.1  million  shares  of  the  Series A  Preferred  Stock  outstanding  leaving  a  balance  of 6.6  million  shares  outstanding  as  of December  31,  2016.    In 2017,  the
Company  issued 0.3  million  additional  shares  of  Preferred  Stock  as  a  PIK  dividend  resulting  in  a  balance  of 6.9  million  shares.  Subsequently  in  June  2018,  the  Company
redeemed the remaining outstanding Preferred Stock outstanding leaving no shares outstanding as of December 31, 2018.

Note Q – Impairment

The following table reconciles the asset impairment charges (in thousands), which are recognized in operating expenses in our consolidated statement of operations:

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NEOGENOMICS, INC.

Impairment of HDC Assets
Impairment of Path Logic Assets

Total Impairment

HDC Assets

For the Years Ended December 31,

2018

2017

2016

$

$

—  $
— 

—  $

—  $
— 

—  $

1,902 
1,562 

3,464 

This  impairment  charge  is  related  to  the  Master  License  Agreement  with  Health  Discovery  Corporation.    This  impairment  charge  writes  off  the  HDC  intangible  assets
associated with SVM, LDT, flow cytometry and cytogenetics technologies.  The impairment is primarily the result of the lack of revenues to date, and the disputed license
termination notification received from HDC.  Based on this analysis, the Company determined that the assets were fully impaired, and an impairment loss was recorded for the
unamortized balance of these assets.

Path Logic Assets

This impairment charge is associated with our Path Logic intangible assets, consisting of customer relationships.  Based on the analysis performed, this asset is fully impaired.

Note R – Segment Information

We have two primary types of customers, Clinical and Pharma.  Our Clinical customers include community based pathology practices, oncology groups, hospitals and academic
centers.  Our Pharma customers include pharmaceutical companies to whom we provide testing and other services to support their studies and clinical trials.

We have presented the financial information reviewed by the Chief Operating Decision Maker (“CODM”) including revenues, cost of revenue and gross margin for each of our
operating  segments.    The  segment  information  presented  in  these  financial  statements  has  been  conformed  to  present  segments  on  this  revised  basis  for  all  prior
periods.  Balance sheet accounts are not presented at the segment level as that information is not used by the CODM.  

The following table summarizes segment information for the years ended December 31, 2018, 2017 and 2016 (in thousands).  

Net Revenues:
Clinical Services
Pharma Services

Total Revenue
Cost of Revenue:
Clinical Services
Pharma Services

Total Cost of Revenue

Gross Margin:
Clinical Services
Pharma Services

Total Gross Margin

For the Years Ended December 31,

2018

2017 
(as adjusted)

2016 
(as adjusted)

241,873  $
34,868 

276,741  $

128,297  $
21,179 

149,476  $

113,576  $
13,689 

127,265  $

213,097  $
27,154 

240,251  $

121,785  $
16,510 

138,295  $

91,313  $
10,643 

101,956  $

210,159 
21,649 

231,808 

120,437 
13,267 

133,704 

89,722 
8,382 

98,104 

$

$

$

$

$

$

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Note T – Quarterly Financial Data (Unaudited)

Supplementary Data

Selected Quarterly Financial Data (unaudited) (in thousands, except per share data)

Net revenues
Gross margin
Net income (loss)
Deemed dividends on preferred stock and amortization of preferred stock
beneficial conversion feature and gain on redemption of preferred stock

Net income (loss) available to common stockholders
Net income (loss) per common share:

Basic
Diluted

Weighted average common shares outstanding –
   Basic
Weighted average shares outstanding –
   Diluted

 (1) Reflects the acquisition of Genoptix in December 2018

Net revenues
Gross margin
Net income (loss)
Deemed dividends on preferred stock and amortization of preferred stock
beneficial conversion feature

Net (loss) available to common stockholders
Net (loss) per common share:

Basic
Diluted

Weighted average common shares outstanding –
   Basic
Weighted average shares outstanding –
   Diluted

End of Financial Statements

$
$
$

$

$

$
$

$
$
$

$

$

$
$

03/31/18

06/30/18

09/30/18

12/31/2018 (1)

For the Quarters Ended

63,423  $
27,303  $
644  $

2,856  $

(2,212) $

(0.03) $
(0.03) $

80,507 

80,507 

67,746  $
30,530  $
(380) $

(6,304) $

5,924  $

0.07  $
0.07  $

81,017 

90,168 

69,097  $
32,321  $
2,023  $

—  $

2,023  $

0.02  $
0.02  $

87,253 

90,899 

76,475  $
37,111  $
353  $

—  $

353  $

0.00  $
0.00  $

93,270 

96,874 

03/31/17

06/30/17

09/30/17

12/31/17

For the Quarters Ended

57,428  $
22,948  $
(1,165) $

2,566  $

(3,731) $

(0.05) $
(0.05) $

78,650 

78,650 

62,264  $
27,352  $
483  $

2,639  $

(2,156) $

(0.03) $
(0.03) $

79,413 

79,413 

59,137  $
24,895  $
(4,264) $

2,651  $

(6,915) $

(0.09) $
(0.09) $

79,617 

79,617 

61,422  $
26,762  $
4,549  $

2,691  $

1,858  $

0.02  $
0.02  $

86,676 

88,611 

Total

2018

276,741 
127,265 
2,640 

(3,448)

6,088 

0.07 
0.07 

85,618 

91,568 

Total

2017

240,251 
101,956 
(396)

10,547 

(10,943)

(0.14)
(0.14)

79,426 

79,426 

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ITEM 9. CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL DISCLOSURE

None.

ITEM 9A. CONTROLS AND PROCEDURES

Evaluation of Disclosure Controls and Procedures

Under the supervision and with the participation of our management, including our Chief Executive Officer and Chief Financial Officer, we evaluated the effectiveness of our
disclosure  controls  and  procedures  as  of  December  31,  2018.    Based  upon  that  evaluation,  our  Chief  Executive  Officer  and  Chief  Financial  Officer  concluded  that,  as  of
December 31, 2018, our disclosure controls and procedures were (1) effective in that they were designed to ensure that material information relating to us, and information
required to be disclosed in our reports to the SEC, including our consolidated subsidiaries, is made known to our Chief Executive Officer and Chief Financial Officer by others
within  those  entities,  particularly  during  the  period  in  which  this  report  was  being  prepared,  as  appropriate  to  allow  timely  discussions  and  decisions  regarding  required
disclosure therein and (2) effective, in that they provide reasonable assurance that information required to be disclosed by us in the reports that we file or submit under the
Exchange Act is recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and forms.

Management’s Report on Internal Control over Financial Reporting

Our management, with the participation of our Chief Executive Officer and Chief Financial Officer, is responsible for establishing and maintaining adequate internal control
over financial reporting. Internal control over financial reporting is defined in Rules 13a-15(f) or 15d-15(f) promulgated under the Exchange Act as a process designed by, or
under the supervision of, our principal executive and principal financial officer and effected by the Company’s board of directors, management and other personnel, to provide
reasonable  assurance  regarding  the  reliability  of  financial  reporting  and  the  preparation  of  financial  statements  for  external  purposes  in  accordance  with  generally  accepted
accounting  principles  and  includes  those  policies  and  procedures:  (1)  that  pertain  to  the  maintenance  of  records  that  in  reasonable  detail  accurately  and  fairly  reflect  the
transactions  and  dispositions  of  the  assets  of  the  Company;  (2)  provide  reasonable  assurance  that  transactions  are  recorded  as  necessary  to  permit  preparation  of  financial
statements  in  accordance  with  generally  accepted  accounting  principles,  and  that  receipts  and  expenditures  of  the  Company  are  being  made  only  in  accordance  with
authorizations of management and directors of the Company; and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use or
disposition of the Company’s assets that could have a material effect on the financial statements.

Because of its inherent limitations, however, internal control over financial reporting may not prevent or detect misstatements. Projections of any evaluation of effectiveness to
future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures
may deteriorate. Our management assessed the effectiveness of the Company’s internal control over financial reporting as of December 31, 2018. The acquisition of Genoptix
occurred in the fourth quarter of 2018; therefore, management has excluded Genoptix from its assessment of internal control over financial reporting as of December 31, 2018.
Genoptix  is  a  wholly-owned  subsidiary  of  NeoGenomics,  Inc.  whose  total  assets  and  total  revenue  represented 33.0%  and 1.7%,  respectively,  of  the  related  consolidated
financial  statement  amounts  as  of  and  for  the  year  ended  December  31,  2018.  In  making  this  assessment,  our  management  used  the  criteria  set  forth  by  the  Committee  of
Sponsoring Organizations of the Treadway Commission (COSO) in Internal Control—
Integrated Framework (2013 Framework). Based on our assessment, management, with the participation of our Chief Executive Officer and Chief Financial Officer, concluded
that, as of December 31, 2018, our internal control over financial reporting was effective based on those criteria at the reasonable  assurance  level.  The  effectiveness  of  our
internal control over financial reporting as of December 31, 2018 has been audited by Crowe LLP, an independent registered public accounting firm, as stated and attested to in
their report that is included in Item 8.

Changes in Internal Control over Financial Reporting

In connection with the adoption of ASU 2014-09 in the first quarter of 2018, we implemented new internal controls over revenues. These changes have not materially affected,
or are reasonably likely to materially affect, the Company’s internal control over financial reporting.

ITEM 9B. OTHER INFORMATION

None.

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PART III

ITEM 10. DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE

The  information  required  by  this  Item  10  will  be  included  under  the  captions  “Election  of  Directors”,  “Information  as  to  Nominees  and  Other  Directors”,  “Information
Regarding Meetings and Committees of the Board”, “Section 16(a) Beneficial Ownership Reporting Compliance” and as otherwise, set forth in the Company’s 2019 Proxy
Statement and is incorporated herein by reference.

ITEM 11. EXECUTIVE COMPENSATION

The information required by this Item 11 will be included under the captions “Executive Compensation and Other Information” and “Compensation Committee Interlocks and
Insider Participation” and as otherwise set forth in the Company’s 2019 Proxy Statement and is incorporated herein by reference.

ITEM 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS

The information required by this Item 12 will be included under the captions “Security Ownership” and “Equity Compensation Plan Information” and as otherwise set forth in
the Company’s 2019 Proxy Statement and is incorporated herein by reference.  

ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS AND DIRECTOR INDEPENDENCE

The information required by this Item 13 will be included under the captions “Certain Relationships and Related Party Transactions” and “Information Regarding Meetings and
Committees of the Board” and as otherwise set forth in the Company’s 2019 Proxy Statement and is incorporated herein by reference.  

ITEM 14. PRINCIPAL ACCOUNTING FEES AND SERVICES

The information required by this Item 14 will be included under the caption “Independent Auditors” and as otherwise set forth in the Company’s 2019 Proxy Statement and is
incorporated herein by reference.

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ITEM 15. EXHIBITS AND FINANCIAL STATEMENT SCHEDULES

Financial Statements: See Index to Consolidated Financial Statements under Part II, Item 8 of this Annual Report on Form 10-K

Exhibit
No.

   Description of Exhibit

   Location

PART IV

2.1 

2.2 

2.3 

  Stock Purchase Agreement, dated as of October 20, 2015, by and among

NeoGenomics Laboratories, Inc. and GE Medical Holding AB

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on October 26, 2015

  Amendment No. 1 to Stock Purchase Agreement, dated as of December 28,

2015, by and among NeoGenomics Laboratories, Inc. and GE Medical
Holding AB

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on December 31, 2015

Agreement and Plan of Merger, dated October 23, 2018 by and among Genesis
Acquisition Holdings Corp., NeoGenomics Laboratories, Inc., Genoptix
Merger Sub, Inc. and Ampersand 2014 Limited Partnership, solely in its
capacity as representative of the stockholders of the Company 

Incorporated by reference to the Company's current report on Form 8-K as
filed with the SEC on October 26, 2018

3.1 

   Articles of Incorporation, as amended

   Incorporated by reference to the Company’s Registration Statement on Form

SB-2 as filed with the SEC on February 10, 1999

3.2 

3.3 

3.4 

   Amendment to Articles of Incorporation filed with the Nevada Secretary of

State on January 3, 2002

   Incorporated by reference to the Company’s Annual Report on Form 10-KSB

for the year ended December 31, 2002, as filed with the SEC on May 20,
2003

   Amendment to Articles of Incorporation filed with the Nevada Secretary of

State on April 11, 2003

   Incorporated by reference to the Company’s Annual Report on Form 10-KSB

for the year ended December 31, 2002, as filed with the SEC on May 20,
2003

  Amendment to Articles of Incorporation filed with the Nevada Secretary of

State on December 28, 2015

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on December 31, 2015

3.5 

  Certificate of Designation of Series A Convertible Preferred Stock

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on December 31, 2015

3.6 

  Amended and Restated Bylaws

3.7 

  Amendment to Amended and Restated Bylaws

  Incorporated by reference to the Company’s Current Report on Form 8-K, as

filed with the SEC on October 17, 2014

  Incorporated by reference to the Company’s Quarterly Report on Form 10-Q
for the quarterly period ended September 30, 2015, as filed with the SEC on
November 6, 2015

10.1 

10.2 

10.3 

   Amended and Restated Registration Rights Agreement between

NeoGenomics, Inc. and Aspen Select Healthcare, L.P. and individuals dated
March 23, 2005

   Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on March 30, 2005

  Amended and Restated Security Agreement between NeoGenomics, Inc. and

Aspen Select Healthcare, L.P., dated March 30, 2006

  Incorporated by reference to the Company’s Annual Report on Form 10-KSB

for the year ended December 31, 2005, as filed with the SEC on April 3,
2006

  Registration Rights Agreement between NeoGenomics, Inc. and Aspen Select

Healthcare, L.P., dated March 30, 2006

  Incorporated by reference to the Company’s Annual Report on Form 10-KSB

for the year ended December 31, 2005, as filed with the SEC on April 3,
2006

10.4 

  Subscription Documents

  Incorporated by reference to the Company’s Registration Statement on Form

SB-2 as filed with the SEC on July 6, 2007

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10.5 

  Investor Registration Right Agreement

  Incorporated by reference to the Company’s Registration Statement on Form

SB-2 as filed with the SEC on July 6, 2007

10.6*

10.7 

10.8*

10.9*

  Employment Agreement, dated March 16, 2009 between Mr. Douglas M.

VanOort and NeoGenomics, Inc.

  Incorporated by reference to the Company’s Quarterly Report on Form 10-Q
for the quarterly period ended June 30, 2010, as filed with the SEC on August
16, 2010

  Subscription Agreement dated March 16, 2009 between the Douglas M.

VanOort Living Trust and NeoGenomics, Inc.

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on March 20, 2009

  Amended and Restated Employment Agreement dated October 28, 2009

between NeoGenomics, Inc. and Douglas M. VanOort

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on November 3, 2009

  Employment Letter dated November 3, 2009 between NeoGenomics

Laboratories, Inc. and George Cardoza

  Incorporated by reference to the Company’s Quarterly Report on Form 10-Q
for the quarterly period ended June 30, 2010, as filed with the SEC on August
16, 2010

10.10 

  Amended and Restated Consulting Agreement dated November 4, 2016

between NeoGenomics, Inc. and Steven C. Jones.

  Incorporated by reference to the Company’s Quarterly Report on Form 10-Q
for the quarterly period ended September 30, 2016, as filed with the SEC on
November  7, 2016

10.11 

  Master License Agreement, dated January 6, 2012, between NeoGenomics

Laboratories, Inc. and Health Discovery Corporation

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on January 11, 2012

10.12*

  Offer Letter between NeoGenomics Laboratories, Inc. and Steven Ross dated

April 19, 2013

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on April 23, 2013

10.13 

  Confidentiality, Non-Solicitation and Non-Compete Agreement dated April

22, 2013 between NeoGenomics Laboratories, Inc. and Steven Ross

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on April 23, 2013

10.14*

10.15 

10.16 

10.17*

10.18*

10.19

10.20 

  Employment Agreement, dated September 18, 2014 by and between

NeoGenomics, Inc. and Robert J. Shovlin

  Incorporated by reference to Exhibit 10.1 to the Company’s Current Report on

Form 8-K as filed with the SEC on October 3, 2014

  Confidentiality, Non-Solicitation and Non-Compete Agreement, dated
September 18, 2014 by and between NeoGenomics, Inc. and Robert J.
Shovlin

  Incorporated by reference to Exhibit 10.2 to the Company’s Current Report on

Form 8-K as filed with the SEC on October 3, 2014

  Engagement Letter between Aspen Capital Advisors, LLC and NeoGenomics,

Inc. dated November 11, 2015.

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on November 17, 2015

  Amended and Restated Equity Incentive Plan effective as of October 15,

2015.

  Incorporated by reference to the Company’s Annual Report on Form 10-K for
the year ended December 31, 2015, as filed with the SEC on March 15, 2016

  Amendment No. 1 of the Amended and Restated Equity Incentive Plan,

  Incorporated by reference to the Company’s Proxy Statement, dated April 24,

effective as of May 25, 2017.

2017, as filed with the SEC on April 25, 2017

  Form of Indemnification Agreement between NeoGenomics, Inc. and each of

its executive officers and directors.

  Incorporated by reference to the Company’s Quarterly Report on Form 10-Q
for the quarterly period ended September 30, 2016, as filed with the SEC on
November 7, 2016

  Credit Agreement, dated December 22, 2016, by and among NeoGenomics
Laboratories, Inc., NeoGenomics, Inc. and certain of its subsidiaries, the
lenders party thereto and Regions Bank, as administrative agent

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on December 27, 2016

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10.21 

10.22 

14.1 

First Amendment to Credit Agreement by and Among NeoGenomics
Laboratories, Inc., NeoGenomics, Inc. and certain of its subsidiaries, the
lenders party thereto and Regions Bank, as administrative agent

Second Amendment to Credit Agreement by and Among NeoGenomics
Laboratories, Inc., NeoGenomics, Inc. and certain of its subsidiaries, the
lenders party thereto and Regions Bank, as administrative agent

Incorporated by reference to the Company’s Current Report on Form 8-K as
filed with the SEC on March 23, 2018

Incorporated by reference to the Company’s Current Report on Form 8-K as
filed with the SEC on June 25, 2018

  NeoGenomics, Inc. Code of Ethics for Senior Financial Officers and the

Principal Executive Officer

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on July 20, 2011

21.1 

  Subsidiaries of NeoGenomics, Inc.

23.1 

  Consent of Crowe, LLP

  Incorporated by reference to the Company’s Annual Report on Form 10-K for
the year ended December 31, 2018, as filed with the SEC on February 26,
2019

  Incorporated by reference to the Company’s Annual Report on Form 10-K for
the year ended December 31, 2018, as filed with the SEC on February 26,
2019

31.1 

31.2 

32.1**

  Certification by Principal Executive Officer pursuant to Rule 13a-14(a)/ 15d-
14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

  Provided herewith

  Certification by Principal Financial Officer pursuant to Rule 13a-14(a)/ 15d-
14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

  Provided herewith

  Certification by Principal Executive Officer and Principal Financial Officer

pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002

  Provided herewith

101 

†

*
**

99.1 

  Charter of the Compliance Committee

99.2 

  Charter of the Nominating and Corporate Governance Committee

  The following materials from the Company’s Annual Report on Form 10-K for
the year ended December 31, 2018 formatted in Extensible Business Reporting
Language (XBRL): (i) the Consolidated Balance Sheets, (ii) the Consolidated
Statements of Operations, (iii) the Consolidated Statements of Stockholders
Equity (iv) the Consolidated Statements of Cash Flows and (v) related notes.

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on October 17, 2014

  Incorporated by reference to the Company’s Current Report on Form 8-K as

filed with the SEC on October 17, 2014

  Incorporated by reference to the Company’s Annual Report on Form 10-K for

the year ended December 31, 2018, as filed with the SEC on February 26,
2019

Portions of the exhibit have been omitted pursuant to a request for confidential treatment pursuant to Rule 24b-2 promulgated under the Exchange Act. The
omitted information has been filed separately with the SEC.
Denotes a management contract or compensatory plan or arrangement.
The certification attached as Exhibit 32.1 that accompanies this Form 10-K/A is not deemed filed with the SEC and is not to be incorporated by reference into any
filing of NeoGenomics, Inc. under the Securities Act or the Exchange Act, whether made before or after the date of this Form 10-K, irrespective of any general
incorporation language contained in such filing.

102

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Table of Contents

NEOGENOMICS, INC.

SIGNATURES

Pursuant  to  the  requirements  of  Section  13  or  15(d)  of  the  Securities  Exchange Act  of  1934,  the  registrant  has  duly  caused  this  report  to  be  signed  on  its  behalf  by  the
undersigned thereunto duly authorized.

Date: May 8, 2019

NEOGENOMICS, INC.

By:

Name:
Title:

  /s/ Douglas M. VanOort
  Douglas M. VanOort
  Chief Executive Officer

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of the registrant and in the capacities
and on the dates indicated.

Signatures

Title(s)

Date

/s/ Douglas M. VanOort

Douglas M. VanOort

/s/ Sharon A. Virag

Sharon A. Virag

/s/ Kathryn B. McKenzie

Kathryn B. McKenzie

/s/ Steven C. Jones

Steven C. Jones

/s/ Lynn A. Tetrault

Lynn A. Tetrault

/s/ Raymond R. Hipp

Raymond R. Hipp

/s/ Bruce K. Crowther

Bruce K. Crowther

  Chairman of the Board and Chief Executive Officer (Principal Executive

  May 8, 2019

Officer)

  Chief Financial Officer (Principal Financial Officer)

  May 8, 2019

Principal Accounting Officer

  May 8, 2019

Director

  Director

  Director

  Director

103

May 8, 2019

  May 8, 2019

  May 8, 2019

  May 8, 2019

 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
EXHIBIT 31.1

I, Douglas VanOort, certify that:

1. I have reviewed this Annual Report on Form 10-K/A (Amendment No. 1) of NeoGenomics, Inc.;

CERTIFICATIONS

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of
the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results
of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-
15(e) and 15d-15(e)), and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material
information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this
report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide
reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted
accounting principles;

(c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure

controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the
registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over
financial reporting; and

5. The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors
and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely

affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial

reporting.

May 8, 2019

/s/ Douglas M. VanOort
Douglas M. VanOort
Chief Executive Officer, Executive Chairman and
Chairman of the Board

 
 
 
 
EXHIBIT 31.2

I, Sharon A. Virag, certify that:

1. I have reviewed this Annual Report on Form 10-K/A (Amendment No. 1) of NeoGenomics, Inc.;

CERTIFICATIONS

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of
the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results
of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-
15(e) and 15d-15(e)), and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material
information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this
report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide
reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted
accounting principles;

(c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure

controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the
registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over
financial reporting; and

5. The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors
and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely

affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial

reporting.

May 8, 2019

/s/ Sharon A. Virag
Sharon A. Virag
Chief Financial Officer

 
 
 
 
CERTIFICATION PURSUANT TO
18 U.S.C. SECTION 1350
AS ADOPTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

EXHIBIT 32.1

In connection with the Annual Report of NeoGenomics, Inc. (the “Company”) on Form 10-K/A (Amendment No. 1) for the fiscal year ended December 31, 2018 as filed

with the Securities and Exchange Commission on the date hereof (the “Report”), each of the undersigned, in the capacities and on the dates indicated below, hereby certify
pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that to his knowledge:

1. The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

2. The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Date: May 8, 2019

Date: May 8, 2019

/s/Douglas M. VanOort

Douglas M. VanOort

Chief Executive Officer

/s/Sharon A. Virag

Sharon A. Virag

Chief Financial Officer

The foregoing certification is being furnished solely to accompany the Report pursuant to 18 U.S.C. § 1350, and is not being filed for purposes of Section 18 of the Securities
Exchange Act of 1934, as amended, and is not to be incorporated by reference into any filing of the Company, whether made before or after the date hereof, regardless of any
general incorporation language in such filing. A signed original of this written statement required by Section 906, or other document authenticating, acknowledging, or
otherwise adopting the signature that appears in typed form within the electronic version of this written statement required by Section 906, has been provided to the Company
and will be retained by the Company and furnished to the Securities and Exchange Commission or its staff upon request.