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Novabay Pharmaceuticals

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FY2015 Annual Report · Novabay Pharmaceuticals
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2015 annual report

A   V I S I O N   F O R   T H E   F U T U R E   O F   E Y E   C A R E

UNITED STATES 
SECURITIES AND EXCHANGE COMMISSION 
Washington, D.C. 20549 
FORM 10-K 

(Mark One) 
☒ 

ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 

For the fiscal year ended December 31, 2015 
OR 

☐ 

TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 

For the transition period from                     to 
Commission file number 001-33678 
NOVABAY PHARMACEUTICALS, INC. 
(Exact name of registrant as specified in its charter) 

Delaware 
(State or other jurisdiction of incorporation or organization) 

68-0454536 
(I.R.S. Employer Identification No.) 

5980 Horton Street, Suite 550, Emeryville CA 94608 
(Address of principal executive offices) (Zip Code) 
Registrant’s Telephone Number, Including Area Code: (510) 899-8800 
Securities registered pursuant to Section 12(b) of the Act: 

Title of each class 
Common Stock, $0.01 par value per share 

Name of each exchange on which registered 
NYSE Mkt 

Securities registered pursuant to Section 12(g) of the Act: None 

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes ☐    No ☒ 

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes ☐    No ☒ 

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities 
Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and 
(2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐ 

Indicate  by  check  mark  whether  the  registrant  has  submitted  electronically  and  posted  on  its  corporate  Web  site,  if  any,  every 
Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for 
such shorter period that the registrant was required to submit and post such files). Yes ☒ No ☐ 

Indicate by a check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will 
not be contained, to the best of registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III 
of this Form 10-K or any amendment to this Form 10-K. ☐ 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller 
reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of 
the Exchange Act. (Check one): 

Large accelerated filer ☐ 
Non-accelerated filer ☐ 

Accelerated filer ☐ 
Smaller reporting company ☒ 

(Do not check if a smaller reporting company) 

Indicate by check mark whether the registrant is a shell company (as defined in Exchange Act Rule 12b-2). Yes ☐ No ☒ 

As of June 30, 2015, the aggregate market value of the voting stock held by non-affiliates of the registrant, computed by reference to 
the last sale price of such stock as of such date on the NYSE Mkt, was approximately $38,118,763. This figure excludes an aggregate of 
532,441 shares of common stock held by officers and directors as of June 30, 2015. Exclusion of shares held by any of these persons should 
not be construed to indicate that such person possesses the power, direct or indirect, to direct or cause the direction of the management or 
policies of the registrant, or that such person is controlled by or under common control with the registrant. 

As of February 29, 2016, there were 5,003,257 shares of the registrant’s common stock outstanding. 

DOCUMENTS INCORPORATED BY REFERENCE 

Part III incorporates information by reference from the Proxy Statement for the 2016 Annual Meeting of Stockholders expected to 

be held in June 2016. 

 
 
   
   
 
NOVABAY PHARMACEUTICALS, INC. 
ANNUAL REPORT ON FORM 10-K 
FOR THE FISCAL YEAR ENDED DECEMBER 31, 2015 

TABLE OF CONTENTS 

Page 

PART I 
ITEM 1.  BUSINESS ....................................................................................................................................................  1 
ITEM 1A.  RISK FACTORS ...........................................................................................................................................  6 
ITEM 1B.  UNRESOLVED STAFF COMMENTS ........................................................................................................  17 
PROPERTIES ...............................................................................................................................................  17 
ITEM 2. 
ITEM 3. 
LEGAL PROCEEDINGS..............................................................................................................................  17 
ITEM 4.  MINE SAFETY DISCLOSURES .................................................................................................................  17 

PART II 
ITEM 5.  MARKET FOR REGISTRANT’S COMMON EQUITY, RELATED STOCKHOLDER MATTERS 

AND ISSUER PURCHASES OF EQUITY SECURITIES .......................................................................  17 
SELECTED FINANCIAL DATA .................................................................................................................  19 

ITEM 6. 
ITEM 7.  MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS 

OF OPERATIONS .....................................................................................................................................  20 
ITEM 7A.  QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK ..............................  30 
ITEM 8. 
FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA ..............................................................  31 
ITEM 9.  CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND 

FINANCIAL DISCLOSURE ....................................................................................................................  59 
ITEM 9A  CONTROLS AND PROCEDURES ..............................................................................................................  59 
ITEM 9B.  OTHER INFORMATION .............................................................................................................................  59 

PART III 
ITEM 10.  DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE .......................................  60 
ITEM 11.  EXECUTIVE COMPENSATION.................................................................................................................  60 
ITEM 12.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND 

RELATED STOCKHOLDER MATTERS ................................................................................................  60 

ITEM 13.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR 

INDEPENDENCE .....................................................................................................................................  60 
ITEM 14.  PRINCIPAL ACCOUNTING FEES AND SERVICES ................................................................................  60 

PART IV 
ITEM 15.  EXHIBITS, FINANCIAL STATEMENT SCHEDULES .............................................................................  60 

Unless the context requires otherwise, all references in this report to “we,” “our,” “us,” the “Company” and “NovaBay” 

refer to NovaBay Pharmaceuticals, Inc. and its subsidiaries. 

NovaBay®, NovaBay Pharma®, Avenova®, NeutroPhase®, CelleRx®, AgaNase®, Aganocide®, AgaDerm®, Neutrox™ and 
Going Beyond Antibiotics® are trademarks of NovaBay Pharmaceuticals, Inc. All other trademarks and trade names are the 
property of their respective owners. 

On December 18, 2015, the Company effected a 1-for-25 reverse split of its common stock. The accompanying financial 

statements and related notes give retroactive effect to this reverse stock split. 

 
 
  
  
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
  
  
  
  
  
  
SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS 

This report contains forward-looking statements that are based on our management’s beliefs and assumptions and on 
information  currently  available  to  our  management.  These  forward-looking  statements  include,  but  are  not  limited  to, 
statements  regarding  our  product  candidates,  market  opportunities,  competitions,  strategies,  anticipated  trends  and 
challenges in our business and the markets in which we operate, and anticipated expenses and capital requirements. In some 
cases,  you  can  identify  forward-looking  statements  by  terms  such  as  “anticipates,”  “believes,”  “could,”  “estimates,” 
“expects,”  “intends,”  “may,”  “plans,”  “potential,”  “predicts,”  “projects,”  “should,”  “will,”  “would”  and  similar 
expressions intended to identify forward-looking statements. Forward-looking statements involve known and unknown risks, 
uncertainties and other factors that may cause our actual results, performance or achievements to be materially different 
from any future results, performances or achievements expressed or implied by the forward-looking statements. We discuss 
many of these risks in this report in greater detail under the heading “Risk Factors” in Item 1A of this report. Given these 
uncertainties, you should not place undue reliance on these forward-looking statements. You should read this report and the 
documents that we reference in this report and have filed as exhibits to the report completely and with the understanding that 
our actual future results may be materially different from what we expect. Also, forward-looking statements represent our 
management’s beliefs and assumptions only as of the date of this report. Except as required by law, we assume no obligation 
to update these forward-looking statements publicly, or to update the reasons actual results could differ materially from 
those anticipated in these forward-looking statements, even if new information becomes available in the future. 

PART I 

ITEM 1. BUSINESS 

Overview  

We are a biopharmaceutical company developing products for the eye care market. We are currently focused primarily 

on commercializing prescription Avenova® for managing hygiene of the eyelids and lashes in the United States.  

Avenova is the only eye care product formulated with a proprietary, stable and pure form of hypochlorous acid called 
Neutrox™. By replicating the anti-microbial chemicals used by white blood cells to fight infection, Neutrox has proven in 
laboratory testing to have broad antimicrobial properties. Avenova with Neutrox removes debris from the skin on the eyelids 
and lashes without burning or stinging. 

In November 2015, we introduced a new business strategy to focus on growing sales of Avenova in the U.S. market and 
to restructure our business with the goal of achieving profitability from operations by the end of 2016. Our three-part business 
strategy is comprised of: (1) focusing our resources on growing the commercial sales of Avenova in the U.S. eye care market, 
including the implementation of an innovative sales and marketing strategy to increase product margin and profitability; (2) 
significantly reducing expenses through the restructuring of our operations and other cost reduction measures; and (3) seeking 
additional sources of revenue through partnering, divesting and/or other means of monetizing non-core assets in urology, 
dermatology, and wound care.  

We have developed additional commercial products containing Neutrox, including our NeutroPhase® Skin and Wound 
Cleanser for wound care and CelleRx® for the dermatology market. We have partnerships for NeutroPhase in the U.S. as well 
as select overseas markets, most notably China.  

In  addition  to  our  Neutrox  family  of  products,  we  have  also  synthesized  and  developed  a  second  category  of  novel 
compounds aimed at harnessing the power of white blood cell chemistry to address the global, topical anti-infective market. 
This  second  product  category  includes  auriclosene,  our  lead  clinical-stage  Aganocide®  compound,  which  is  a  patented, 
synthetic molecule with a broad spectrum of activity against bacteria, viruses and fungi.  

We were incorporated under the laws of the State of California on January 19, 2000, as NovaCal Pharmaceuticals, Inc., 
and subsequently changed our name to NovaBay Pharmaceuticals, Inc. In June 2010, we changed the state in which we are 
incorporated  (the  “Reincorporation”)  to  the  State  of  Delaware.  All  references  to  “we,”  “us,”  “our,”  “the  Company,”  or 
NovaBay” herein refer to the California corporation prior to the date of the Reincorporation, and to the Delaware corporation 
on and after the date of the Reincorporation.  

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Avenova 

Sales and Marketing  

Prescription Avenova (0.01% Neutrox) is well-suited for daily eyelid and eyelash hygiene by approximately 30 million 
Americans who suffer from blepharitis and dry eye. Additionally, we estimate that an additional 11 million patients suffering 
from other conditions could potentially benefit from the use of Avenova, bringing the total potential market to approximately 
41 million patients.  

A growing number of patients have found Avenova, which is used twice daily, to be soothing and effective in removing 
microorganisms and debris that can cause inflammation, itching and other painful symptoms of the eyelids and lashes. As 
described below, many key opinion leaders in the field of ophthalmology and optometry have embraced Avenova as a tool 
in the management of lid and lash hygiene.  

We  are  targeting  a  customer  base  of  prescribers  that  includes  the  approximately  17,000  ophthalmologists  and 
approximately 37,000 optometrists in the U.S. In August 2014, we launched a dedicated Avenova sales force of 10 direct 
medical sales representatives in 10 major metropolitan areas across the United States. This sales and marketing campaign 
initially targeted major urban areas where large numbers of individuals suffer from problems with their eyelids and lashes. 
These markets included New York, Los Angeles, Boston, Atlanta, and San Francisco. 

In January 2015, we rebranded our product originally known as i-Lid Cleanser as Avenova in order to more clearly 
differentiate  this  prescription  product  from  over-the-counter  (OTC)  detergent-based  lid  wipes.  Our  prescription-only 
Avenova offers advantages as a part of the regimen for managing these disorders compared with alternative regimens that 
contain soaps, bleach and other impurities. Avenova removes micro-organisms from the skin without the use of harmful 
ingredients like detergents and bleach. 

Based on positive sales performance, we expanded our sales force to 35 direct medical sales representatives in February 
2015 and to 43 direct medical sales representatives in August 2015. The sales representatives recruited for this effort have 
extensive experience with eye care products and medical devices—a skill set critical for rapid adoption of Avenova. Based 
on extensive market research, we have assigned our sales representatives to the markets across the U.S. representing the 
highest sales potential. These direct medical sales representatives are calling on targeted ophthalmologists and optometrists 
in  those  markets.  These  targeted  doctors  treat  large  numbers  of  blepharitis  and  dry  eye  patients.  Avenova  is  a  natural 
addition to their existing lid hygiene regimens.  

We have distribution agreements with McKesson Corporation, Cardinal Health and AmerisourceBergen Corporation 
that make Avenova accessible in 90% of the approximate 67,000 retail pharmacies across the U.S. Avenova also is marketed 
through the top ophthalmology and optometry networks. These include Vision Source Independent Optometry Network, the 
largest  independent optometry  network  in the  country  representing 2,800  independent  optometrist  offices,  and ALLDocs 
Optometry Group (also known as The Association of LensCrafters Leaseholding Doctors), the second largest independent 
optometry group in the U.S., which works closely with its LensCrafters partners. Through a partnership with ALPHAEON, 
Avenova  is  available  to  member  ophthalmologists  on  the  ShoutMD®  Store,  the  first  social  commerce  store  for  lifestyle 
healthcare products. Avenova is also available for order online with a prescription, and we provide an online pharmacy locator 
to assist patients with filling prescriptions.  

We expect continued benefit from the support of the key opinion leaders on our Ophthalmic and Optometry Advisory 
Boards, our active schedule of educational and marketing programs and strong presence at major eye care conferences in the 
coming months, including the American Academy of Ophthalmology, the American Optometric Association, the American 
Society of Cataract and Refractive Surgery Conferences and the South Eastern Congress of Optometry, as well as numerous 
Vision Expo meetings held around the U.S. We also plan to continue advertising in leading ophthalmic and optometric trade 
journals. At meetings, in professional publications and in surveys, nationally prominent ophthalmologists and optometrists 
are reporting on improvements in eye care from the use of Avenova.  

We  reported  increases  in  key  metrics  throughout  2015,  including  the  number  of  optometrists  and  ophthalmologists 
purchasing Avenova for their practices. We also reported growth in prescription volume as reported by distributors and the 
number of retail pharmacies ordering Avenova, both of which have been confirmed by third-party prescription data providers. 
Increases in Avenova volume include growth of both Avenova product reorders and new prescriptions.  

We expect that our prescription business will be the main driver of long-term Avenova sales growth. Reimbursement 
under insurance coverage continues to grow with 68% of Avenova prescriptions covered by insurance plans at the end of 
2015.  Supported  by  the  high  percentage  rate  of  insurance  reimbursement,  we  are  focusing  our  primary  sales  efforts  on 

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building our prescription business under a new value pricing model. We are working to improve insurance reimbursement 
coverage for Avenova and aligning our product pricing accordingly. 

Although we are focusing on our prescription sales, we expect continued growth in the doctor to patient direct sales 
channel. We also expect to invest in systems that support prescribing physicians’ efforts to educate their patients. We have 
made it easy for doctors to get Avenova into the hands of patients by providing availability through well-known national 
pharmacy chains, specialty pharmacies, or directly through the practitioners’ office. Furthermore, in order to ensure consistent 
pricing, we have instituted rebate cards to ensure the best price for the patient at the pharmacy. This sales model combined 
with the prospect for further increases in reimbursement under insurance plans has the potential to provide us with additional 
revenue upside.  

Competition 

Our Avenova product is competing in the lid and lash hygiene market. Avenova has the distinct competitive advantage 
of  being  the  only  product  for  the  management  of  eye  conditions  that  contains  our  proprietary  Neutrox,  which  is  pure 
hypochlorous acid. Neutrox was cleared by the U.S. FDA as a prescription medical device for the cleansing and removal of 
microorganisms from wounds and skin.  

There are many companies that sell lid and lash scrubs, most of these are surfactant (soap) based, such as lid scrubs or 
baby shampoos. Prescription Avenova has been shown to neutralize bacterial toxins in vitro and is designed for continuous 
daily  eyelid  hygiene.  Unlike  its  competitors,  Avenova  consists  of  saline  and  0.01%  pure  hypochlorous  acid,  without  the 
bleach  impurities  included  in  competitive  offerings.  Newer  prescription  products  have  more  recently  been  commercially 
launched; however, all include bleach or other impurities. We believe that physicians and their patients will choose Avenova 
over competitive prescription products or diluted soap, such as some OTC products.  

Partnerships to Monetize Other Assets 

We  intend  to  seek  additional  sources  of  revenue  and  reduce  expenses  by  licensing  or  selling  select  non-core  assets, 

possibly including intelli-Case, NeutroPhase, CelleRx and our Aganocide compounds, including auriclosene. 

Currently, the program with the most potential is our urology program. Statistically-significant and clinically-meaningful 
results from a Phase 2 clinical study of our Auriclosene Irrigation Solution (AIS) used to reduce urinary catheter blockage 
and encrustation (UCBE), were announced in September 2013. This study, comparing AIS to saline solution, achieved its 
primary endpoints and showed clear benefits for patients with long-term indwelling catheters. We initiated the next Phase 2 
study in the fourth quarter of 2014, and in the fourth quarter of 2015, we announced completion of that study. Patients with 
long-term indwelling urinary catheters were treated with AIS or its Vehicle. The results of this more demanding study showed 
that AIS was better than its Vehicle in preventing the reduction of flow through catheters due to encrustation, the primary 
efficacy measure, by a statistically-significant margin. Furthermore, there were no cases of clinical catheter blockage in the 
AIS arm of the study; all cases of clinical blockage requiring catheter removal occurred only in the Vehicle arm. 

NovaClear intelli-Case 

In June 2015, we received FDA-clearance for the NovaClear intelli-Case, a highly innovative, easy-to-use device for use 
with  hydrogen  peroxide  disinfection  solutions  for  soft  and  rigid  gas  permeable  contact  lenses.  More  than  24  million 
Americans disinfect their contact lenses with a multipurpose disinfection system to prevent potentially serious infections. 
Approximately two million use hydrogen peroxide as a disinfection solution. Many ophthalmologists and optometrists favor 
the disinfection and lens material compatibility peroxide systems provide, yet side effects associated with misuse and non-
compliance minimize peroxide system use. Hydrogen peroxide in too low of a concentration does not fully disinfect lenses 
and in too high of a concentration can irritate the eye. 

The  intelli-Case  monitors  the  neutralization  of  hydrogen  peroxide  during  the  disinfection  cycle  with  sophisticated 
microprocessor  electronics  embedded  in  the  cap  of  what  otherwise  looks  like  a  standard  peroxide  lens  case.  The  LED 
indicators on the lid inform the user if the lenses are safe to insert into the eyes, resulting in a disinfection system that is safe 
yet simple to use. We are seeking potential partners with the resources to make this break-through device available to the 
largest number of contact lens wearers as soon as possible.  

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Additional Neutrox-based Products 

Although  Avenova  with  Neutrox  is  NovaBay’s  primary  commercial  focus,  over  the  past  ten  years  NovaBay  has 
developed  additional  Neutrox-related  products.  In  addition  to  Avenova,  the  Neutrox  branded  products  currently  being 
commercialized as prescription medical devices are NeutroPhase and CelleRx. Similar to Avenova, we believe the principal 
competitive  advantage of  these  products  in our  target  markets  is  the fact  that in-vitro  studies  show  their  effectiveness  in 
killing bacteria, fungi and viruses, including bacteria in biofilm; very low potential for the development of resistance; fast 
time to kill bacteria; a wide safety margin; a low side-effect profile and cost effectiveness.  

NeutroPhase  (Wound  Care).  Since  its  launch  in  the  U.S.  in  2013,  NeutroPhase  has  impacted  how  wound  care  is 
administered. Consisting of 0.03% Neutrox, NeutroPhase is used to cleanse and remove microorganisms from any type of 
acute or chronic wound, and can be used with any type of wound care modality. Recently, NeutroPhase has been found to be 
an effective irrigation solution as part of the adjunct treatment for Necrotizing Fasciitis (“NF”). Also known as flesh-eating 
disease, NF typically has a high mortality and amputation rate (30% and 70%, respectively) even with aggressive debridement 
and antibiotic treatment. In vitro studies have shown that in solution, NeutroPhase both kills the microorganisms implicated 
in NF and neutralizes the toxins secreted by the microorganisms. Success using NeutroPhase as an irrigation solution has 
established it as an effective part of the adjunct treatment for this deadly disease. 

We believe that NeutroPhase is a well-suited product to treat the six million patients in the U.S. who suffer from chronic 
non-healing  wounds,  such  as  pressure,  venous  stasis  and  diabetic  ulcers.  In  the  U.S.  and  internationally,  NeutroPhase  is 
distributed through commercial partners. In January 2012, we entered into an exclusive distribution agreement with Pioneer 
Pharma  Company  Limited,  or  “Pioneer,”  a  Shanghai-based  company,  for  the  distribution  of  NeutroPhase  throughout 
Southeast Asia and mainland China. We subsequently expanded the agreement with Pioneer so that it includes the licensing 
rights to CelleRx and Avenova. In September 2014, China’s Food and Drug Administration cleared our NeutroPhase Skin 
and  Wound  Cleanser  for  sale  throughout  mainland  China.  In  November  2014,  Taiwan’s  Food  and  Drug  Administration 
cleared our NeutroPhase Skin and Wound Cleanser for sale in Taiwan. We began shipping NeutroPhase to China and Taiwan 
in  the  fourth  quarter  of  2014  to  support  our  launch  of  NeutroPhase  Skin  and  Wound  Cleanser  by  Pioneer.  In  the  U.S., 
NeutroPhase is distributed through our partner, Principle Business Enterprise (“PBE”). 

In March 2015, the National Necrotizing Fasciitis Foundation (“NNFF”) named NeutroPhase its official “Flesh Eating 
Disease” wound cleanser. The NNFF is a non-profit organization established in 1997 by two survivors of the disease. NNFF 
has evolved to become the world’s leading resource for information regarding necrotizing fasciitis, as well as a repository of 
cases reported worldwide.  

NeutroPhase is competing in a crowded skin and wound cleanser market with many old and low priced products with 
similar uses. However, we believe NeutroPhase has distinct competitive advantages in a market where there is currently no 
dominant product. 

CelleRx (Dermatology). Created for cosmetic procedures, CelleRx™ (0.015% Neutrox) is a gentle cleansing solution 
that is effective for post-laser resurfacing, chemical peels and other cosmetic surgery procedures. Cosmetic surgeons and 
aesthetic dermatologists have found that CelleRx results in less pain, erythema, and exudate compared to Dakin solution, 
which  contains  bleach  impurities.  CelleRx  is  a  non-alcohol  formulation  that  doesn’t  dry  or  stain  the  skin,  and  most 
importantly, has been shown to reduce the patient’s downtime post procedure.  

CelleRx is competing in the cosmetic surgery and aesthetic dermatology space as an adjunct therapy for the pre/post 
procedural phase of chemical and laser facial skin peels. Currently many generic creams and salves, as well as home-mixed 
acetic acid potions, are used for this purpose. We believe that CelleRx is clearly differentiated in this field. CelleRx is the 
only Rx product with 510(k) clearance for use as a skin and wound cleanser that is safe, soothing and has broad spectrum 
antimicrobial action in solution. Many clinicians have used the product clinically and have reported excellent results. 

U.S. FDA Regulatory Clearance of Neutrox-based Products. We are marketing Avenova, NeutroPhase, and CelleRx 
as medical devices regulated under the FDA 510(k) process. Avenova and CelleRx fall under the general intended use of skin 
and wound cleansers. NeutroPhase was cleared by the U.S. FDA “for use under the supervision of healthcare professionals 
for  cleansing  and  removal  of  foreign  material,  including  microorganisms  and  debris  from  wounds,  and  for  moistening 
absorbent wound dressings and cleaning minor cuts, minor burns, superficial abrasions, and minor irritations of the skin. It 
is also intended for moistening and debriding acute and chronic dermal lesions, such as Stage I to IV pressure ulcers, stasis 
ulcers, leg ulcers, diabetic foot ulcers, post-surgical wounds, first and second degree burns, and grafted and donor sites.” 

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Aganocide Compounds 

Our first-in-class Aganocide compounds, led by auriclosene (NVC-422), are patented, synthetic molecules with a broad 
spectrum of activity against bacteria, viruses and fungi.  Mimicking the mechanism of action that human white blood cells 
use against infections, Aganocides possess a reduced likelihood of bacteria or viruses developing resistance, which is critical 
for advanced anti-infectives. The World Health Organization (WHO) approved a new generic nomenclature by which our 
novel compound NVC-422 is identified—auriclosene.  

We believe that our Aganocide compounds may, if approved by the regulatory authorities, have significant advantages 
over  existing  compounds  and  compounds  in  development  because  the  Aganocide  compounds  could  be  used  to  prevent 
infections or to treat infections with bacterial and viral components, such as conjunctivitis.  

Recent Events 

In January 2015, we rebranded i-Lid Cleanser as Avenova® Daily Lid & Lash Hygiene to help differentiate prescription 

Avenova from other marketed eye cleansers, in particular over-the-counter (OTC) products not intended for daily use. 

In January 2015, we attended and sought partners for our Avenova product at Arab Health 2015. Held January 26-29, 
2015, at the Dubai International Convention & Exhibition Centre in the United Arab Emirates, Arab Health 2015, then in its 
40th year, was the largest healthcare conference in the world. 

In January 2015, we signed a nationwide distribution agreement with Cardinal Health, to deliver prescription drugs and 
many other products to retail pharmacies, hospitals, mail-order facilities, physician offices, surgery centers and other facilities 
across the U.S. Under the agreement, Cardinal Health will carry and distribute our Avenova product. 

In February 2015, we expanded our sales force for Avenova from 15 sales representatives to 35 representatives, focusing 

on major markets across the U.S. 

In March 2015, we entered into a securities purchase agreement for the sale of our common stock and warrants in a 

private placement for net proceeds of approximately $4.5 million. 

In March 2015, the NNFF named NeutroPhase its official “Flesh Eating Disease” wound cleanser.  

In April 2015, we sponsored an educational workshop on new ideas for lid management during the ASCRS Annual 
Symposium. There, key opinion leaders in the field of optometry and ophthalmology discussed the practical uses of Avenova 
for the management of blepharitis and dry eye, and as a surgical eye preparation. 

In  April  2015,  we  announced  the  appointment  of  Mark  M.  Sieczkarek  as  Chairman  of  the  Board  of  Directors.  Mr. 
Sieczkarek replaced NovaBay founder Dr. Ramin (Ron) Najafi, who remained a director of the Company. Mr. Sieczkarek 
had served as a director since January 2014 and was instrumental in developing the commercial strategy for Avenova. 

In April 2015, we signed a national distribution agreement with AmerisourceBergen to carry and distribute Avenova to 
retail pharmacies in the U.S. AmerisourceBergen is one the largest global pharmaceutical sourcing and distribution services 
companies.  

In April 2015, the NYSE MKT LLC notified us that NovaBay’s stockholders’ equity as of December 31, 2014 was 
below the minimum requirements of Sections 1003(a)(ii) and (iii) of the NYSE MKT Company Guide. We were advised that 
in order to maintain a listing on the NYSE MKT, we had to submit a plan of compliance by May 28, 2015 addressing how 
we intended to regain compliance within the following 18-month period. 

In May 2015, we announced that data from two studies were discussed in poster presentations at the Annual Meeting of 
the Association for Research in Vision and Ophthalmology (ARVO). One poster was presented by Guru Sharma, OD, Ph.D., 
Optometrist at Family Eye Care Optometry and Assistant Professor at Western University of Health Sciences’ College of 
Optometry,  and  discussed  research  documenting  the  successful  use  of  Avenova  on  patients  with  blepharitis.  The  second 
poster was presented by Arthur Epstein, OD, FAAO, FABCO, FBCLA, DPNAP, co-founder and head of the Dry Eye–Ocular 
Surface Disease Center and Director of Clinical Research at Phoenix Eye Care, and found that Avenova was the only product 
of six widely-used commercial eyelid treatments with the ability to neutralize bacterial lipase, a major cause of blepharitis 
and meibomian gland dysfunction (MGD).  

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In May 2015, we entered into a securities purchase agreement for the sale of our common stock and warrants in a private 

placement for net proceeds of approximately $6.3 million.  

In June 2015, we announced FDA approval for intelli-Case, a novel, high-tech device for safely disinfecting contact 

lenses with hydrogen peroxide.  

In July 2015, the New York Stock Exchange accepted our plan to regain compliance with the NYSE MKT’s continued 

listing standards by October 28, 2016. 

In September 2015, we entered into an agreement with ALLDocs Optometry Group, also known as The Association of 
LensCrafters  Leaseholding  Doctors,  to  market  Avenova  to  this  group’s  optometrists.  ALLDocs  is  the  second  largest 
independent optometry group in the U.S. 

In  September  2015,  we  entered  into  a  partnership  with  ALPHAEON  Corporation  to  make  Avenova  available  for 

purchase by member doctors on the ShoutMD® Store, the first social commerce store for lifestyle healthcare production.  

In October 2015, we completed an underwritten public offering for the sale of our common stock and warrants for net 

proceeds of approximately $2.1 million.  

In November 2015, we announced the completion of a 34-patient Phase 2b clinical trial with auriclosene (NVC-422) to 

reduce urinary catheter blockage and encrustation in patients with long-term indwelling urinary catheters.  

In November 2015, we announced a restructuring aimed at reducing expenses and achieving positive cash flow from 
operations by the end of 2016. In conjunction with the announcement, Dr. Najafi resigned his position and our Chairman 
Mark M. Sieczkarek assumed the role of Interim Chief Executive Officer and President.  

In  December  2015,  our  Board  of  Directors  approved  and  we  implemented  a  1-for-25  reverse  stock  split  in  order  to 
maintain continued listing standards with the NYSE MKT. The reverse split was authorized by our stockholders at a special 
stockholder meeting held December 11, 2015.  

In December 2015 and January 2016, we entered into a series of promissory notes for an aggregate $3,020,000 bridge 

loan with a three-year term and no pre-payment penalty. 

In February 2016, we closed a private placement for the sale of an aggregate of 1,518,567 shares of the Company’s 

common stock for total gross proceeds amount of $2,830,804. 

Employees 

As of December 31, 2015, we had 23 full-time and 3 part-time employees. None of our employees are represented by 
labor unions or covered by collective bargaining agreements. We consider our relationship with our employees to be good. 

Available Information 

Our annual reports on Form 10-K, quarterly reports on Form 10-Q, current reports on Form 8-K, and amendments to 
those reports filed or furnished pursuant to Sections 13(a) and 15(d) of the Securities Exchange Act of 1934, as amended, are 
available free of charge on our corporate website, located at www.novabay.com, as soon as reasonably practicable after we 
electronically file such material with, or furnish it to, the Securities and Exchange Commission (SEC). 

ITEM 1A.  RISK FACTORS 

Our business is subject to a number of risks, the most important of which are discussed below. You should consider 
carefully the following risks in addition to the other information contained in this report and our other filings with the SEC 
before deciding to buy, sell or hold our common stock. The risks and uncertainties described below are not the only ones 
facing our Company. Additional risks and uncertainties not presently known to us or that we currently believe are immaterial 
may also impair our business operations. If any of the following risks actually occur, our business, financial condition or 
results of operations could be materially adversely affected, the value of our common stock could decline and you may lose 
all or part of your investment. 

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Risks Relating to Our Liquidity 

There is uncertainty about our ability to continue as a going concern. 

We have a limited number of commercial products, and these products are still in their early stage of commercialization 
and will require significant additional investment before we realize substantial revenue. As a result, we have incurred since 
our inception, and expect to continue to incur until at least the end of 2016, substantial net losses. Moreover, our cash position 
is inadequate to support our current business operations and substantial additional funding will be needed in order to pursue 
our  business  plan,  which  includes  increasing  market  penetration  for  our  existing  commercial  products,  research  and 
development  for  additional  product  offerings  for  the  eye  care  market,  seeking  regulatory  approval  for  these  product 
candidates, and pursuing their commercialization in the U.S., Asia, and other markets. These circumstances raise substantial 
doubt about our ability to continue as a going concern, which depends on our ability to raise capital to fund our current 
operations.  

We  have  a  history  of  losses  and  expect  that  we  will  incur  net  losses  in  the  future,  and  that  we  may  never  achieve  or 
maintain sustained profitability.  

We expect to incur substantial marketing and sales expenses as we attempt to increase sales of our Avenova product. We 
expect to incur losses for the foreseeable future, and we may never achieve or maintain sustained profitability. In addition, at 
this time we are subject to the following risks:   

●  our results of operations may fluctuate significantly, which may adversely affect the value of an investment in our

common stock;  

    ●  we may be unable to develop and commercialize our product candidates; and  

    ● 

it may be difficult to forecast accurately our key operating and performance metrics because of our limited operating
history. 

We will need to generate significant revenues to achieve and maintain profitability. If we cannot successfully market 
and sell Avenova, either independently or with partners, we will not be able to generate sufficient revenues to achieve or 
maintain  profitability  in  the  future.  Our  failure  to  achieve  and  subsequently  maintain  profitability  could  have  a  material 
adverse impact on the market price of our common stock. 

We may be unable to raise additional capital on acceptable terms in the future, which may in turn limit our ability to 
develop and commercialize products and technologies. 

While we have reduced our staff levels and reduced both our research and general expenditures, we believe our capital 
outlays  and  operating  expenditures  will  outsize  our  expected  near-term  revenue.  Commercializing  a  product  is  very 
expensive,  and  we  expect  that  we  will  need  to  raise  additional  capital,  through  future  private  or  public  equity  offerings, 
strategic alliances or debt financing, before we achieve a breakeven point between expenses and product sales. In addition, 
we may require even more significant capital outlays and operating expenditures if we do not continue to partner with third 
parties to develop and commercialize our products. 

Our future capital requirements will depend on many factors, including: 

    ● 

the availability and willingness of capital markets to fund our planned operations; 

    ● 

economic conditions out of our control; 

    ●  market acceptance and revenue growth of Avenova; 

    ● 

the extent to which we receive milestone payments or other funding from external partners, if any; 

● 

the  scope,  rate  of  progress,  cost  and  results  of  our  pre-clinical  studies  and  clinical  trials  and  other  research  and
development activities, if any; 

    ● 

the terms and timing of any collaborative, licensing and other arrangements that we may establish; 

    ● 

the cost and timing of regulatory approvals; 

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● 

the cost of establishing clinical and commercial supplies of our product candidates and any products that we may
develop; 

    ● 

the effect of competing technological and market developments; 

    ● 

the costs associated with marketing and selling Avenova and NeutroPhase; 

    ● 

the cost of filing, prosecuting, defending and enforcing any patent claims and other intellectual property rights; and 

● 

the extent to which we acquire or invest in businesses, products and technologies, although we currently have no
commitments or agreements relating to any of these types of transactions. 

Additional financing may not be available to us on favorable terms, or at all. The securities rules and regulations limit 
our sale of securities registered on a Form S-3 to one-third of the aggregate market value of our outstanding common equity 
held by non-affiliates (the “Aggregate Market Value”) during a 12-month period as long as our Aggregate Market Value is 
below $75 million. In our October 2015 public offering of common stock and accompanying warrants to purchase common 
stock, we utilized substantially all of our remaining capacity to sell securities on Form S-3 at the time and we currently have 
no capacity to sell additional securities on Form S-3. Until our Aggregate Market Value reaches $75 million, our ability to 
raise capital on Form S-3 is limited, especially during the period through October 2016. As a result, we may have to raise 
capital on a Form S-1 registration statement, which requires more disclosure than the Form S-3, would cause additional legal 
and other expenses, and could delay the timing of any future offerings. Even after October 2016, we may not be able to raise 
the amount of capital we need on a Form S-3 if our low Aggregate Market Value persists. 

In connection with our bridge loan financing completed in January 2016, we granted China Kington Asset Management 
Co. Ltd. (“China Kington”) a first right of refusal to lead our financings for a period that is the shorter of two years after the 
bridge loan financing or until our net cash flow has been no less than $0 for three consecutive months. Such financings must 
be unanimously approved by our Board of Directors, which includes two members nominated by China Kington pursuant to 
the bridge loan arrangement, until the bridge loan is paid off. As a result of these restrictions, we might not be able to obtain 
additional capital we need, or on the most favorable terms. Even if we are able to obtain such capital, the proceeds must be 
used to repay the bridge loan first before being used for our business. 

Our ability to obtain additional financing may also be negatively affected by the recent volatility in the financial markets, 
as well as the general downturn in the economy and decreased consumer confidence. Even if we succeed in selling additional 
securities to raise funds, our existing stockholders’ ownership percentage would be diluted and new investors may demand 
rights, preferences or privileges senior to those of existing stockholders. In addition, if in the future we sell, or grant options 
or rights to purchase, our common stock at an effective price per share less than the subsequently adjusted exercise price of 
our  warrants  originally  issued  in  July  2011,  March  2015  and  October  2015,  the  exercise  price  of  these  warrants  will  be 
reduced  to  equal  such  lower price,  subject  to  certain  exemptions  as provided  in  the warrants.  The  exercise price of such 
warrants  is  currently  set  at  $1.81  as  a  result  of  the  Company’s  February  2016  private  placement  offering.  See  “—If  we 
conduct offerings in the future, the price at which we offer our securities is likely to trigger a price protection provision 
included in warrants originally issued in July 2011, March 2015 and October 2015, reducing the probability and magnitude 
of any future share price appreciation.” 

If we raise additional capital through strategic alliance and licensing arrangements, we may have to trade our rights to 
our technology, intellectual property or products to others on terms that may not be favorable to us. If we raise additional 
capital through debt financing, the financing may involve covenants that restrict our business activities. 

Risks Relating to Owning Our Common Stock 

If  our  stockholders’  equity  does  not  meet  the  minimum  standards  of  the  NYSE  MKT,  we  may  be  subject  to  delisting 
procedures. 

On April 28, 2015, we received a letter from the NYSE MKT notifying us that our stockholders' equity as of December 
31, 2014 was below the minimum requirements of Sections 1003(a)(ii) and (iii) of the NYSE MKT Company Guide. In order 
to maintain our listing, we submitted a plan of compliance, addressing how we intend to regain compliance with the Company 
Guide within 18 months, or by November 28, 2016. We continue our listing but will be subject to periodic reviews by the 
exchange. If we do not make progress consistent with the plan, the exchange will initiate delisting procedures, as appropriate.  

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We are pursuing options to address the stockholders’ equity deficiency as indicated in our plan submitted to the NYSE 
MKT. However, we cannot guarantee that we will be able to comply with the listing requirements, and therefore our common 
stock may be subject to delisting. If our common stock is delisted, this could, among other things, substantially impair our 
ability to raise additional funds; result in a loss of institutional investor interest and fewer financing opportunities for us; 
and/or  result  in  potential  breaches  of  representations  or  covenants  of  our  warrants,  subscription  agreements  or  other 
agreements  pursuant  to  which  we  made  representations  or  covenants  relating  to  our  compliance  with  applicable  listing 
requirements. Claims related to any such breaches, with or without merit, could result in costly litigation, significant liabilities 
and diversion of our management's time and attention and could have a material adverse effect on our financial condition, 
business and results of operations.  

If  we  conduct  offerings  in  the  future,  the  price  at  which  we  offer  our  securities  is  likely  to  trigger  a  price  protection 
provision included in warrants originally issued in July 2011, March 2015 and October 2015, reducing the probability 
and magnitude of any future share price appreciation. 

As part of our October 2015 offering, we agreed to amend certain terms of the warrants we previously issued in July 
2011 and March 2015 to certain investors. As a result, in four different sets of warrants issued in July 2011, March 2015 and 
October 2015, we agreed to provide certain price protections affecting warrants exercisable for an aggregate of 1,317,227 
shares of our common stock, of which 874,425 shares must be issued, if at all, by March 6, 2020, and 442,802 shares must 
be issued, if at all, by October 27, 2020. Specifically, in the event that we undertake a third-party equity financing of either: 
(1) common stock at a sale price of less than $5.00 per share; or (2) convertible securities with an exercise price of less than 
$5.00 per share, we have agreed to reduce the exercise price of all warrants discussed hereof to such lower price. As a result, 
if any future offering is conducted at a common stock price or warrant exercise price under $5.00 per share (as adjusted for 
any reverse stock split or similar transaction), these price protections will be triggered. The exercise price of such warrants 
is currently set at $1.81 as a result of the Company’s February 2016 private placement offering. The further reduction of the 
exercise price for the warrants discussed hereto would limit the probability and magnitude of future share price appreciation, 
if  any, by placing  downward  pressure on  our  stock  price if  it  exceeds  such offering  sale  price. All of  these warrants  are 
currently exercisable and will remain so after any exercise price adjustment. In the past, we have extended the expiration 
dates or adjusted other terms of previously-issued warrants as consideration for certain offering conditions, and we cannot 
assure you that we will not do so in the future. Any such modifications would reduce the probability and magnitude of any 
share  price  appreciation  during  the  period  of  the  extension.  We  cannot  guarantee  that  you  will  receive  a  return  on  your 
investment when you do sell your shares or that you will not lose the entire amount of your investment. If you do receive a 
return on your investment, it may be lower than the return you would have realized in the absence of the price protection 
provisions discussed hereof. 

The price of our common stock may fluctuate substantially, which may result in losses to our stockholders. 

The stock prices of many companies in the pharmaceutical and biotechnology industry have generally experienced wide 
fluctuations, which are often unrelated to the operating performance of those companies. The market price of our common 
stock is likely to be volatile and could fluctuate in response to, among other things: 

    ● 

successful shifting in strategy to focus on the eye care market; 

    ● 

the announcement of new products by us or our competitors; 

    ● 

the announcement of partnering arrangements by us or our competitors; 

    ●  quarterly variations in our or our competitors’ results of operations; 

    ● 

announcements by us related to litigation; 

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● 

changes in our earnings estimates, investors’ perceptions, recommendations by securities analysts or our failure to
achieve analysts’ earnings estimates; 

    ●  developments in our industry; and 

●  general, economic and market conditions, including the recent volatility in the financial markets and decrease in
consumer confidence and other factors unrelated to our operating performance or the operating performance of our
competitors. 

The volume of trading of our common stock may be low, leaving our common stock open to the risk of high volatility. 

The number of shares of our common stock being traded may be very low. Any stockholder wishing to sell his/her stock 
may cause a significant fluctuation in the price of our stock. We have a number of large stockholders, including our principal 
stockholder Pioneer. The sale of a substantial number of shares of common stock by such large stockholders within a short 
period of time could cause our stock price to decrease substantially. In addition, low trading volume of a stock increases the 
possibility that, despite rules against such activity, the price of the stock may be manipulated by persons acting in their own 
self-interest. We may not have adequate market makers and market making activity to prevent manipulation. 

Our  amended  and  restated  certificate  of  incorporation  and  bylaws  and  Delaware  law  contain  provisions  that  could 
discourage a third party from making a takeover offer that is beneficial to our stockholders. 

Anti-takeover provisions of our amended and restated certificate of incorporation, amended and restated bylaws and 
Delaware law may have the effect of deterring or delaying attempts by our stockholders to remove or replace management, 
engage in proxy contests and effect changes in control. The provisions of our charter documents include: 

    ● 

a classified board so that only one of the three classes of directors on our Board of Directors is elected each year; 

    ● 

elimination of cumulative voting in the election of directors; 

    ●  procedures for advance notification of stockholder nominations and proposals; 

    ● 

the ability of our Board of Directors to amend our bylaws without stockholder approval; and 

● 

the ability of our Board of Directors to issue up to 5,000,000 shares of preferred stock without stockholder approval
upon  the  terms  and  conditions  and  with  the  rights,  privileges  and  preferences  as  our  Board  of  Directors  may
determine. 

In  addition,  as  a  Delaware  corporation,  we  are  subject  to  the  Delaware  General  Corporation  Law,  which  includes 
provisions that may have the effect of deterring hostile takeovers or delaying or preventing changes in control or management 
of our Company. Provisions of the Delaware General Corporation Law could make it more difficult for a third party to acquire 
a  majority  of  our  outstanding  voting  stock  by  discouraging  a  hostile  bid,  or  delaying,  preventing  or  deterring  a  merger, 
acquisition or tender offer in which our stockholders could receive a premium for their shares, or effect a proxy contest for 
control of NovaBay or other changes in our management. 

We have not paid dividends in the past and do not expect to pay dividends in the future, and any return on investment may 
be limited to the value of our stock. 

We have never paid cash dividends on our common stock and do not anticipate paying cash dividends on our common 
stock  in  the  foreseeable  future.  The  payment  of  dividends  on  our  common  stock  will  depend  on  our  earnings,  financial 
condition and other business and economic factors affecting us at such time as our Board of Directors may consider relevant. 
If we do not pay dividends, you will experience a return on your investment in our shares only if our stock price appreciates. 
We cannot assure you that you will receive a return on your investment when you do sell your shares or that you will not lose 
the entire amount of your investment. 

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Pioneer  and China  Kington  might  influence our  corporate matters  in a manner  that  is  not  in  the best  interest  of our 
general stockholders. 

As of February 29, 2016, Pioneer beneficially owns approximately 22% of our common stock. Our director Mr. Xinzhou 
“Paul” Li is the chief executive officer and chairman of Pioneer. Pursuant to the arrangement of our bridge loan financing 
completed in January 2016, two of our directors were nominated by China Kington, including Mr. Mijia “Bob” Wu, who is 
the Managing Director of China Kington and Non-Executive Director of Pioneer, and Mr. Xiaoyan “Henry” Liu, who has 
worked closely with China Kington on other financial transactions in the past.  

As a result, Pioneer and China Kington have input on all  matters before our Board of Directors and  may be able to 
exercise significant influence over all matters requiring board and stockholder approval. In particular, under our bridge loan 
arrangement, for a period that is the shorter of two years after the bridge loan financing or until our net cash flow has been 
no less than $0 for three consecutive months, our financings must be unanimously approved by our Board of Directors, which 
provides Pioneer and China Kington a veto right over such financings. See “We may be unable to raise additional capital on 
acceptable terms in the future, which may in turn limit our ability to develop and commercialize products and technologies.” 
Pioneer and China Kington may choose to exercise their influence in a manner that is not in the best interest of our general 
stockholders. 

Our ability to use our net operating loss carryforwards and certain other tax attributes may be limited.  

Under Section 382 of the Internal Revenue Code of 1986, as amended, if a corporation undergoes an “ownership change,” 
generally defined as a greater than 50% change (by value) in its equity ownership over a three year period, the corporation’s 
ability to use its pre-change net operating loss carryforwards and other pre-change tax attributes (such as research tax credits) 
to offset its post-change income may be limited. Since the Company’s formation, the Company has raised capital through the 
issuance of capital stock on several occasions which, combined with the purchasing shareholders’ subsequent disposition of 
those shares, may have resulted in one or more changes of control, as defined by Section 382. The Company has not currently 
completed a study to assess whether any change of control has occurred, or whether there have been multiple changes of 
control since the Company’s formation, due to the significant complexity and cost associated with the study. If the Company 
has  experienced  a  change  of  control  at  any  time  since  its  formation,  its  NOL  carryforwards  and  tax  credits  may  not  be 
available, or their utilization could be subject to an annual limitation under Section 382. In addition, since we will need to 
raise substantial additional funding to finance our operations, we may undergo further ownership changes in the future. In 
the future, if we earn net taxable income, our ability to use our pre-change net operating loss carryforwards to offset United 
States federal taxable income may be subject to limitations, which could potentially result in increased future tax liability  
to us.  

Risks Relating to Our Business 

Our future success is largely dependent on the successful commercialization of Avenova. 

The  future  success  of  our  business  is  largely  dependent  upon  the  successful  commercialization  of  Avenova.  We  are 
dedicating a substantial amount of our resources to advance Avenova as aggressively as possible. If we encounter difficulties 
in the commercialization of Avenova, we will not have the resources necessary to continue our business in its current form. 
If we are unable to establish and maintain adequate sales, marketing and distribution capabilities or enter into or maintain 
agreements with third parties to do so, we may be unable to successfully commercialize our products. We believe we are 
creating  an  efficient  commercial  organization,  taking  advantage  of  outsourcing  options  where  prudent  to  maximize  the 
effectiveness of our commercial expenditures. However, we may not be able to correctly judge the size and experience of the 
sales  and  marketing  force  and  the  scale  of  distribution  necessary  to  be  successful.  Establishing  and  maintaining  sales, 
marketing, and distribution capabilities are expensive and time-consuming. Such expenses may be disproportionate compared 
to the revenues we may be able to generate on sales of Avenova.  

Our commercialized products are not approved by the FDA as a drug, so we rely solely on the 510(k) clearance of Neutrox 
as a medical device. 

Our business and future growth depend on the development, use and sale of products that are subject to FDA regulation, 
clearance  and  approval.  Under  the  U.S.  Federal  Food,  Drug,  and  Cosmetic  Act  and  other  laws,  we  are  prohibited  from 
promoting our products for off-label uses. This means that we may not make claims about the safety or effectiveness of our 
products and may not proactively discuss or provide information on the use of our products, except as allowed by the FDA. 
As a medical device, our claims regarding efficacy are limited. Without claims of efficacy, market acceptance of our products 
may be slow.  

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We may be subject to fines, penalties, injunctions and other sanctions if we are deemed to be promoting the use of our 
products for non-FDA-approved, or off-label, uses. 

There is a risk that the FDA or other federal or state law enforcement authorities could determine that the nature and 
scope of our sales and marketing activities may constitute the promotion of our products for a non-FDA-approved use in 
violation of applicable law. We also face the risk that the FDA or other regulatory authorities might pursue enforcement 
based on past activities that we have discontinued or changed, including sales activities, arrangements with institutions and 
doctors, educational and training programs and other activities.  

Government  investigations  concerning  the  promotion  of  off-label  uses  and  related  issues  are  typically  expensive, 
disruptive  and  burdensome  and  generate  negative  publicity.  If  our  promotional  activities  are  found  to  be  in  violation  of 
applicable law or if we agree to a settlement in connection with an enforcement action, we would likely face significant fines 
and penalties and be required to substantially change our sales, promotion, grant and educational activities. In addition, were 
any enforcement actions against us or our senior officers to arise, we could be excluded from participation in U.S. government 
healthcare programs such as Medicare and Medicaid. 

We do not have our own manufacturing capacity, and we rely on partnering arrangements or third-party manufacturers 
for the manufacture of our products and potential products. 

We do not currently operate manufacturing facilities for production of our product and product candidates. We have no 
experience in product formulation or manufacturing, and we lack the resources and the capabilities to manufacture any of 
our product candidates on a clinical or commercial scale. As a result, we have partnered and expect to partner with third 
parties to manufacture our products or rely on contract manufacturers to supply, store and distribute product supplies for our 
clinical trials. Any performance failure on the part of our commercial partners or future manufacturers could delay clinical 
development or regulatory approval of our product candidates or commercialization of our products, producing additional 
losses and reducing or delaying product revenues. 

Our  products  and  product  candidates  will  require  precise,  high-quality  manufacturing.  The  failure  to  achieve  and 
maintain  high manufacturing  standards,  including  the  incidence of  manufacturing  errors,  could  result in patient  injury  or 
death, product recalls or withdrawals, delays or failures in product testing or delivery, cost overruns or other problems that 
could seriously harm our business. Contract manufacturers and partners often encounter difficulties involving production 
yields, quality control and quality assurance, as well as shortages of qualified personnel. These manufacturers and partners 
are  subject  to  ongoing  periodic  unannounced  inspection  by  the  FDA  and  corresponding  state  agencies  to  ensure  strict 
compliance  with  Quality  Systems  Regulations,  current  Good  Manufacturing  Practice  and  other  applicable  government 
regulations and corresponding foreign standards; however, we do not have control over third-party compliance with these 
regulations and standards. If any of our manufacturers or partners fails to maintain compliance, the production of our products 
could be interrupted, resulting in delays, additional costs and potentially lost revenues. 

In addition, if the FDA or other regulatory agencies approve any of our product candidates for commercial sale, we will 
need to manufacture them in larger quantities. Significant scale-up of manufacturing will require validation studies, which 
the FDA must review and approve. If we are unable to successfully increase the manufacturing capacity for a product, the 
regulatory approval or commercial launch of any products may be delayed or there may be a shortage in supply and our 
business may be harmed as a result. 

We  depend  on  skilled  and  experienced  personnel  and  management  leadership  to  operate  our  business  effectively  and 
maintain our investor relationships. If we are unable to retain, recruit and hire such key employees, especially our next 
President  and  CEO,  our  ability  to  manage  our  business  will  be  harmed,  which  would  impair  our  future  revenue  and 
profitability. Creating a reliable revenue stream depends on our ability to manage an effective staff. 

Our success largely depends on the skills, experience and efforts of our officers and other key employees. The efforts of 
our officers and other key employees are critical to us as we continue to focus on the commercialization of our Avenova 
product with the goal of achieving positive cash flow from operations by the end of 2016.  Any of our officers and other key 
employees may terminate their employment at any time, and the loss of any of our senior management team members could 
disrupt our business and affect key partnerships.  

Recently, on November 18, 2015, our former President and CEO, Dr. Ramin “Ron” Najafi, resigned from NovaBay and 
our Chairman of the Board, Mark M. Sieczkarek, was appointed as Interim President and CEO. We do not intend to retain 
Mr. Sieczkarek in a long-term executive capacity, and his employment agreement expires on March 31, 2016, with three-
month renewal periods that cannot be extended beyond November 18, 2016 by its terms. If we fail to identify, attract and 
hire a strong candidate to serve as our next President and CEO, or if we are unable to manage the transition to a new President 

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and CEO, our ability to manage our business will be harmed. The execution of our business strategy, and thus our future 
revenue and profitability, depends on our ability to successfully manage this transition. 

We intend to rely on a limited number of pharmaceutical wholesalers to distribute Avenova.  

We intend to rely primarily upon pharmaceutical wholesalers in connection with the distribution of Avenova. If we are 
unable to establish or maintain our business relationships with these pharmaceutical wholesalers on commercially acceptable 
terms, it could have a material adverse effect on our sales and may prevent us from achieving profitability. 

If we grow and fail to manage our growth effectively, we may be unable to execute our business plan. 

Our future growth, if any, may cause a significant strain on our management and our operational, financial and other 
resources. Our ability to grow and manage our growth effectively will require us to implement and improve our operational, 
financial and management information systems and to expand, train, manage and motivate our employees. These demands 
may require the hiring of additional management personnel and the development of additional expertise by management. 
Any increase in resources devoted to research and product development without a corresponding increase in our operational, 
financial and management information systems could have a material adverse effect on our business, financial condition, and 
results of operations. 

Government agencies may establish usage guidelines that directly apply to our products or proposed products or change 
legislation or regulations to which we are subject. 

Government usage guidelines typically address matters such as usage and dose, among other factors. Application of 
these guidelines could limit the use of our products and products that we may develop. In addition, there can be no assurance 
that government regulations applicable to our products or proposed products or the interpretation thereof will not change and 
thereby prevent the marketing of some or all of our products for a period of time or permanently. The FDA’s policies may 
change and additional government regulations may be enacted that could modify, prevent or delay regulatory approval of our 
product candidates. We cannot predict the likelihood, nature or extent of adverse government regulation that may arise from 
future legislation or administrative action, either in the U.S. or in other countries. 

We and our collaborators are and will be subject to ongoing FDA obligations and continued regulatory review, such as 
continued  safety  reporting  requirements,  and  we  and  our  collaborators  may  also  be  subject  to  additional  FDA  post-
marketing obligations or new regulations, all of which may result in significant expense and which may limit our ability 
to commercialize our medical devices and drug products and candidates. 

Any regulatory approvals that we receive may also be subject to limitations on the indicated uses for which the product 
may be marketed or contain requirements for potentially costly post-marketing follow-up studies. The FDA may require us 
to commit to perform lengthy post marketing studies, which would require us to expend additional resources and thus could 
have an adverse effect on our operating results and financial condition. In addition, if the FDA approves any of our drug 
product candidates, the labeling, packaging, adverse event reporting, storage, advertising, promotion and record keeping for 
the drug will be subject to extensive regulatory requirements. The subsequent discovery of previously unknown problems 
with the drugs, including adverse events of unanticipated severity or frequency, may result in restrictions on the marketing 
of the drugs or the withdrawal of the drugs from the market. If we are not able to maintain regulatory compliance, we may 
be  subject  to  fines,  suspension  or  withdrawal  of  regulatory  approvals,  product  recalls,  seizure  of  products,  operating 
restrictions and criminal prosecution. Any of these events could prevent us from marketing any products we may develop 
and our business could suffer. 

Our past clinical trials may expose us to expensive liability claims, and we may not be able to maintain liability insurance 
on reasonable terms or at all. 

Even though we have concluded all our clinical trials, an inherent risk remains. If a claim were to arise in the future 
based on our past clinical trial activity, we would most likely incur substantial expenses. Our inability to obtain sufficient 
clinical trial insurance at an acceptable cost to protect us against potential clinical trial claims could prevent or inhibit the 
commercialization of our product candidates. Our current clinical trial insurance covers individual and aggregate claims up 
to $5.0 million. This insurance may not cover all claims and we may not be able to obtain additional insurance coverage at a 
reasonable cost, if at all, in the future. In addition, if our agreements with any future corporate collaborators entitle us to 
indemnification  against  product  liability  losses  and  clinical  trial  liability,  such  indemnification  may  not  be  available  or 
adequate should any claim arise. 

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The pharmaceutical and biopharmaceutical industries are characterized by patent litigation, and any litigation or claim 
against us may impose substantial costs on us, place a significant strain on our financial resources, divert the attention 
of management from our business and harm our reputation. 

There  has  been  substantial  litigation  in  the  pharmaceutical  and  biopharmaceutical  industries  with  respect  to  the 
manufacture, use and sale of new products that are the subject of conflicting patent rights. For the most part, these lawsuits 
relate to the validity, enforceability and infringement of patents. Generic companies are encouraged to challenge the patents 
of pharmaceutical products in the United States because a successful challenger can obtain six months of exclusivity as a 
generic product under the Hatch-Waxman Act. We expect that we will rely upon patents, trade secrets, know-how, continuing 
technological innovations and licensing opportunities to develop and maintain our competitive position, and we may initiate 
claims to defend our intellectual property rights as a result. Other parties may have issued patents or be issued patents that 
may prevent the sale of our products or know-how or require us to license such patents and pay significant fees or royalties 
to produce our products. In addition, future patents may be issued to third parties which our technology may infringe. Because 
patent applications can take many years to issue, there may be applications now pending of which we are unaware that may 
later result in issued patents that our products may infringe. 

Intellectual property litigation, regardless of outcome, is expensive and time-consuming, would divert management’s 
attention from our business and could have a material negative effect on our business, operating results or financial condition. 
If such a dispute were to be resolved against us, we might be required to pay substantial damages, including treble damages 
and attorney’s fees if we were found to have willfully infringed a third party’s patent, to the party claiming infringement, to 
develop  non-infringing  technology,  to  stop  selling  any  products  we  develop,  to  cease  using  technology  that  contains  the 
allegedly infringing intellectual property or to enter into royalty or license agreements that may not be available on acceptable 
or commercially practical terms, if at all. Our failure to develop non-infringing technologies or license the proprietary rights 
on  a  timely  basis  could  harm  our  business.  Modification  of  any  products  we  develop  or  development  of  new  products 
thereafter could require us to conduct additional clinical trials and to revise our filings with the FDA and other regulatory 
bodies,  which  would  be  time-consuming  and  expensive.  In  addition,  parties  making  infringement  claims  may  be  able  to 
obtain an injunction that would prevent us from selling any products we develop, which could harm our business. 

If product liability lawsuits are brought against us, they could result in costly litigation and significant liabilities.  

Despite all reasonable efforts to ensure safety, it is possible that we or our collaborators will sell products, including 
Avenova, NeutroPhase, and intelli-Case, which are defective, to which patients react in an unexpected manner, or which are 
alleged to have side effects. The manufacture and sale of such products may expose us to potential liability, and the industries 
in which our products are likely to be sold have been subject to significant product liability litigation. Any claims, with or 
without merit, could result in costly litigation, reduced sales, significant liabilities and diversion of our management’s time 
and attention, and could have a material adverse effect on our financial condition, business and results of operations. 

If a product liability claim is brought against us, we may be required to pay legal and other expenses to defend the claim 
and, if the claim is successful, damage awards may not be covered, in whole or in part, by our insurance. We may not have 
sufficient capital resources to pay a judgment, in which case our creditors could levy against our assets. We may also be 
obligated to indemnify our collaborators and make payments to other parties with respect to product liability damages and 
claims.  Defending  any  product  liability  claims,  or  indemnifying  others  against  those  claims,  could  require  us  to  expend 
significant financial and managerial resources. 

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If we are unable to protect our intellectual property, our competitors could develop and market products similar to ours 
that may reduce demand for our products. 

Our success, competitive position and potential future revenues will depend in significant part on our ability to protect 
our intellectual property. We rely on the patent, trademark, copyright and trade secret laws of the U.S. and other countries, 
as  well  as  confidentiality  and  nondisclosure  agreements,  to  protect  our  intellectual  property  rights.  We  apply  for  patents 
covering our technologies as we deem appropriate. 

There is no assurance that any patents issued to us or licensed or assigned to us by third parties will not be challenged, 
invalidated, found unenforceable or circumvented, or that the rights granted thereunder will provide competitive advantages 
to us. If we or our collaborators or licensors fail to file, prosecute or maintain certain patents, our competitors could market 
products that contain features and clinical benefits similar to those of any products we develop, and demand for our products 
could decline as a result. Further, although we have taken steps to protect our intellectual property and proprietary technology, 
third parties may be able to design around our patents or, if they do infringe upon our technology, we may not be successful 
or have sufficient resources in pursuing a claim of infringement against those third parties. Any pursuit of an infringement 
claim by us may involve substantial expense and diversion of management attention. 

We also rely on trade secrets and proprietary know-how that we seek to protect by confidentiality agreements with our 
employees, consultants and collaborators. If these agreements are not enforceable, or are breached, we may not have adequate 
remedies for any breach, and our trade secrets and proprietary know-how may become known or be independently discovered 
by competitors. 

We operate in the State of California. The laws of the State prevent us from imposing a delay before an employee who 
may  have  access  to  trade  secrets  and  proprietary  know-how  can  commence  employment  with  a  competing  company. 
Although we may be able to pursue legal action against competitive companies improperly using our proprietary information, 
we may not be aware of any use of our trade secrets and proprietary know-how until after significant damage has been done 
to our company. 

Furthermore, the laws of foreign countries may not protect our intellectual property rights to the same extent as the laws 
of the U.S. If our intellectual property does not provide significant protection against foreign or domestic competition, our 
competitors, including generic manufacturers, could compete more directly with us, which could result in a decrease in our 
market share. All of these factors may harm our competitive position. 

A  default  under  the  terms  of  our  recent  bridge  loan  could  result  in  the  loss  of  our  intellectual  property,  including 
intellectual property related to Avenova. 

As partial collateral for the approximately $3.0 million bridge loan we obtained in December 2015 and January 2016, 
we granted China Kington, as collateral agent, a lien on all of our intellectual property.  If we default on the bridge loan, 
including by failing to make any payment due pursuant to the loan, China Kington would have the right to foreclose on our 
intellectual  property. We  cannot  successfully  commercialize  Avenova without  control of  the related  intellectual  property 
portfolio.    A  loss  of  such  intellectual  property  would  prevent  us  from  executing  our  current  business  strategy,  which  is 
essential to our efforts to achieve profitability.  For further information regarding the possible risks if we fail to commercialize 
Avenova, please see the risk factor entitled “Our future success is largely dependent on the successful commercialization 
of Avenova.” 

Our current patent portfolio could leave us vulnerable to larger companies who have the resources to develop and market 
competing products.  

We aggressively protect and enforce our patent rights worldwide. However, certain risks remain. There is no assurance 
that patents will issue from any of our applications or, for those patents we have or that do issue, that the claims will be 
sufficiently broad to protect our proprietary rights, or that it will be economically possible to pursue sufficient numbers of 
patents to afford significant protection. For example, we do not have any composition of matter patent directed to the Neutrox 
(hypochlorous  acid)  composition.  This  relatively  weak  patent  portfolio  leaves  us  vulnerable  to  competitors  who  wish  to 
compete in the same marketplace with similar products. If a potential competitor introduces a formulation similar to Avenova 
or NeutroPhase with a similar composition that does not fall within the scope of the method of treatment/manufacture claims, 
then we or a potential marketing partner would be unable to rely on the allowed claims to protect its market position for the 
method of using the Avenova or NeutroPhase composition, and any revenues arising from such protection would be adversely 
impacted.  

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If physicians and patients do not accept and use our products, we will not achieve sufficient product revenues and our 
business will suffer. 

Even if the FDA has cleared or approves product candidates that we develop, physicians and patients may not accept 

and use them. Acceptance and use of our products may depend on a number of factors including: 

●  perceptions by members of the healthcare community, including physicians, about the safety and effectiveness of

our products; 

    ●  published studies demonstrating the cost-effectiveness of our products relative to competing products; 

    ● 

availability of reimbursement for our products from government or healthcare payers; and 

    ● 

effectiveness of marketing and distribution efforts by us and our licensees and distributors, if any. 

The  failure of any of our products  to  find market  acceptance would harm  our  business  and  could require us  to  seek 

additional financing. 

If  we  cannot  compete  successfully  for  market  share  against  other  companies,  we  may  not  achieve  sufficient  product 
revenues and our business will suffer. 

The  market  for  our  products  and  product  candidates  is  characterized  by  intense  competition  and  rapid  technological 
advances. Existing or future competing products may provide greater therapeutic convenience or clinical or other benefits 
for a specific indication than our products, or may offer comparable performance at a lower cost. If our products are unable 
to capture and maintain market share, we may not achieve sufficient product revenues and our business will suffer. 

We compete for market share against fully-integrated pharmaceutical and medical device companies or other companies 
that develop products independently or collaborate with larger pharmaceutical companies, academic institutions, government 
agencies and other public and private research organizations. In addition, many of these competitors, either alone or together 
with  their  collaborative  partners,  have  substantially  greater  capital  resources,  larger  research  and  development  staffs  and 
facilities, and greater financial resources than we do, as well as significantly greater experience in: 

    ●  developing drugs and devices; 

    ● 

conducting preclinical testing and human clinical trials; 

    ●  obtaining FDA and other regulatory approvals of product candidates; 

    ● 

formulating and manufacturing products; and 

    ● 

launching, marketing, distributing and selling products. 

Our competitors may: 

    ●  develop and patent processes or products earlier than we will; 

    ●  develop and commercialize products that are less expensive or more efficient than any products that we may develop;

    ●  obtain regulatory approvals for competing products more rapidly than we will; and 

● 

improve upon existing technological approaches or develop new or different approaches that render any technology
or products we develop obsolete or uncompetitive. 

We  cannot  assure  you  that  our  competitors  will  not  succeed  in  developing  technologies  and  products  that  are  more 
effective than any developed by us or that would render our technologies and any products we develop obsolete. If we are 
unable to compete successfully against current or future competitors, we may be unable to obtain market acceptance for any 
product candidates we create, which could prevent us from generating revenues or achieving profitability and could cause 
the market price of our common stock to decline. 

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Our ability to generate revenues from our current products and any products we develop will be diminished if we fail to 
obtain acceptable prices or an adequate level of reimbursement for our products from healthcare payers. 

Significant uncertainty exists as to the cost and reimbursement status of newly-approved healthcare products. Healthcare 
payers, including Medicare, are challenging the prices charged for medical products and/or are seeking pharmacoeconomic 
data to justify formulary acceptance and reimbursement practices. We currently have not generated pharmacoeconomic data 
on any of our products. If customers and insurance companies are not willing to pay the set price for our products, our revenue 
will be limited. 

ITEM 1B.  UNRESOLVED STAFF COMMENTS 

Not applicable.  

ITEM 2.  PROPERTIES 

Our  principal  executive  offices  and  our  research  and  development  and  administrative  operations  are  located  in 
Emeryville, California. In total, we lease approximately 16,465 square feet of office space in the facility pursuant to a lease 
agreement expiring on October 31, 2020. 

ITEM 3.  LEGAL PROCEEDINGS 

We are currently not a party to, nor is our property the subject matter of, any pending or, to our knowledge, contemplated 
material legal proceedings.  From time to time, we may become party to litigation and subject to claims arising in the ordinary 
course of our business. 

ITEM 4.  MINE SAFETY DISCLOSURES 

Not Applicable. 

PART II 

ITEM 5.  MARKET FOR REGISTRANT’S COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND

ISSUER PURCHASES OF EQUITY SECURITIES 

Market Information  

Our common stock is listed on the NYSE MKT, under the symbol “NBY.” The following table sets forth, for the periods 
indicated, the high and low sales prices for our common stock as reported by the NYSE Mkt, after giving effect to the 25:1 
reverse stock split: 

2015 

2014 

High 

Low 

High 

Low 

First Quarter ..................................................  $ 
Second Quarter ..............................................  $ 
Third Quarter ................................................  $ 
Forth Quarter .................................................  $ 

18.75    $ 
26.25    $ 
17.00    $ 
9.50    $ 

10.50     $ 
12.75     $ 
5.50     $ 
1.75     $ 

36.75    $ 
29.50    $ 
32.50    $ 
21.25    $ 

25.75   
19.50   
17.25   
13.25  

Holders  

As of February 26, 2016, there were approximately 26 holders of record of our common stock. This figure does not 

reflect persons or entities that hold their stock in nominee or “street” name through various brokerage firms. 

Dividend Policy 

We  have  not  paid  cash  dividends  on  our  common  stock  since  our  inception.  We  currently  expect  to  retain  earnings 
primarily for use in the operation and expansion of our business, and therefore, do not anticipate paying any cash dividends 
in the near future. Any future determination to pay cash dividends will be at the discretion of our Board of Directors and will 
be  dependent  upon  our  financial  condition,  results  of  operations,  capital  requirements,  restrictions  under  any  existing 
indebtedness and other factors the Board of Directors deems relevant. 

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Purchase of Equity Securities by the Issuer  

During 2015, we repurchased 237 shares from an employee at price of $0.71 per share to satisfy the statutory withholding 

tax liability upon the vesting of restricted share-based award.  

Performance Graph(1) 

The  following  graph  compares  our  total  stockholder  returns  for  the  past  five  years  to  two  indices:  the  NYSE  MKT 
Composite Index and the RDG MicroCap Biotechnology Index. The total return for each index assumes the reinvestment of 
all dividends, if any, paid by companies included in these indices and are calculated as of December 31 of each year. 

As a member of the NYSE MKT Composite Index, we are required under applicable regulations to use this index as a 
comparator, and we believe the RDG MicroCap Biotechnology Index is a relevant comparator since it is composed of peer 
companies in lines-of-business similar to ours. 

The stockholder return shown on the graph below is not necessarily indicative of future performance, and we do not 

make or endorse any predictions as to future stockholder returns. 

18 

 
  
  
  
  
  
  
 
  
 
 
12/10

12/11 

12/12

12/13

12/14 

12/15

NovaBay Pharmaceuticals, Inc. ........................ 
NYSE MKT Composite ..................................... 
RDG MicroCap Biotechnology ......................... 

100.00
100.00
100.00

80.72 
104.50 
100.77 

68.07
110.18
93.77

74.10
118.63
106.18

37.95 
120.72 
80.01 

4.87
107.77
44.81

(1) This section is not “soliciting material,” is not deemed “filed” with the SEC and is not to be incorporated by reference in 
any of our filings under the Securities Act or the Exchange Act whether made before or after the date hereof and irrespective 
of any general incorporation language in any such filing. 

ITEM 6.   SELECTED FINANCIAL DATA  

The following table presents selected financial information as of and for the dates and periods indicated below which 
have been derived from our audited consolidated financial statements and other information. The information set forth below 
is not necessarily indicative of results of future operations, and should be read in conjunction with “Management’s Discussion 
and Analysis of Financial Condition and Results of Operations” in Part II, Item 7 of this report and our consolidated financial 
statements and related notes included elsewhere in this report. 

Statements of Operations Data: 
Sales: 

2015 

Year Ended December 31, 
2013 
(in thousands, except per share data) 

2012 

2014 

2011 

Product Revenue ...............................................   $

4,146    $ 

684     $

223     $

14     $

—  

Other Revenue ..................................................     
Total Net Sales .....................................................     

Product Cost of Goods Sold .............................     
Gross Profit ..........................................................     

235      
4,381      

1,261      
3,120      

370       
1,054       

3,254       
3,477       

6,933       
6,947       

11,019   
11,019   

486       
568       

162       
3,315       

8       
6,939       

—  
11,019   

Operating expenses: 

Research and development ...............................     
Selling, general and administrative ...................     
Total operating expenses ......................................     
Operating loss.......................................................     
Non-cash gain (loss) on change in fair value of 

warrants ..........................................................     
Other income (expense), net .................................     
Loss before income taxes .....................................     
Provision for income taxes ...................................     

6,045      
18,089      
24,134      
(21,014)     

2,149      
(96)     
(18,961)     
(12)     

9,511       
7,935       
17,446       
(16,878)     

1,664       
22       
(15,192)     
(2)     

12,461       
6,340       
18,801       
(15,486)     

(555)     
1       
(16,040)     
(2)     

9,275       
5,973       
15,248       
(8,309)     

1,439       
(155)     
(7,025)     
(2)     

9,911   
5,429   
15,340   
(4,321) 

(732) 
(30) 
(5,083) 
(2) 

Net loss  ................................................................   $

(18,973)   $ 

(15,194)   $

(16,042)   $

(7,027)   $

(5,085) 

Net loss per share: 

Basic .................................................................   $
Diluted ..............................................................   $

(6.82)   $ 
(6.82)   $ 

(7.65)   $
(7.65)   $

(10.51)   $
(10.51)   $

(5.97)   $
(5.97)   $

Shares used in computing net loss per share: 

Basic (after 1 for 25 reverse stock split) ...........     
Diluted (after 1 for 25 reverse stock split) ........     

2,784      
2,784      

1,985      
1,985      

1,527      
1,527      

1,178      
1,178      

(4.93) 
(4.93) 

1,031  
1,031  

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2015 

2014 

2013 
(in thousands) 

2012 

2011 

Balance Sheet Data: 
Cash, cash equivalents and short-term 

investments ........................................................   $
Working capital ....................................................     
Total assets ...........................................................     
Deferred revenue—current and non-current ........     
Common stock and additional paid-in capital ......     
Total stockholders’ equity (deficit) ......................     

2,385    $
(106)     
5,077      
2,418      
85,422      
(5,098)      

5,429    $ 
3,607      
7,537      
2,425      
73,395      
1,848      

13,053    $
11,163      
15,650      
1,871      
64,884      
8,516      

16,870    $
15,108      
19,235      
1,892      
54,373      
14,049      

14,138  
11,720  
15,963  
2,250  
42,672  
9,344  

ITEM 7.  MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF

OPERATIONS 

The  following  discussion  of  our  financial  condition  and  results  of  operations  should  be  read  together  with  our 
consolidated  financial  statements  and  related  notes  included  in  Part  II,  Item  8  of  this  report.  This  discussion  contains 
forward-looking statements that involve risks and uncertainties. Words such as “expects,” “anticipated,” “will,” “may,” 
“goals,” “plans,” “believes,” “estimates,” “concludes, ”determines,” variations of these words, and similar expressions 
are intended to identify these forward-looking statements. As a result of many factors, including those set forth under the 
section entitled “Risk Factors” in Item 1A and elsewhere in this report, our actual results may differ materially from those 
anticipated  in  these  forward-looking  statements.  Readers  are  cautioned  that  these  forward-looking  statements  are  only 
predictions  based  upon  assumptions  made  that  we  believed  to  be  reasonable  at  the  time,  and  are  subject  to  risks  and 
uncertainties. Therefore, actual results may differ materially and adversely from those expressed in any forward-looking 
statements.  Except  as  required  by  law,  we  undertake  no  obligation  to  revise  or  update  publicly  any  forward-looking 
statements. 

Overview  

We are a biopharmaceutical company developing products for the eye care market. We are currently focused primarily 

on commercializing prescription Avenova® for managing hygiene of the eyelids and lashes in the United States.  

Avenova is the only eye care product formulated with a proprietary, stable and pure form of hypochlorous acid called 
Neutrox™. By replicating the anti-microbial chemicals used by white blood cells to fight infection, Neutrox has proven in 
laboratory testing to have broad antimicrobial properties. Avenova with Neutrox removes debris from the skin on the eyelids 
and lashes without burning or stinging. 

In November 2015, we introduced a new business strategy to focus on growing sales of Avenova in the U.S. market and 
to restructure our business with the goal of achieving profitability from operations by the end of 2016. Our three-part business 
strategy is comprised of: (1) focusing our resources on growing the commercial sales of Avenova in the U.S. eye care market, 
including the implementation of an innovative sales and marketing strategy to increase product margin and profitability; (2) 
significantly reducing expenses through the restructuring of our operations and other cost reduction measures; and (3) seeking 
additional sources of revenue through partnering, divesting and/or other means of monetizing non-core assets in urology, 
dermatology, and wound care.  

We have developed additional commercial products containing Neutrox, including our NeutroPhase® Skin and Wound 
Cleanser for wound care and CelleRx™ for the dermatology market. We have partnerships for NeutroPhase in the U.S. as 
well as select overseas markets, most notably China.  

In  addition  to  our  Neutrox  family  of  products,  we  have  also  synthesized  and  developed  a  second  category  of  novel 
compounds aimed at harnessing the power of white blood cell chemistry to address the global, topical anti-infective market. 
This  second  product  category  includes  auriclosene,  our  lead  clinical-stage  Aganocide®  compound,  which  is  a  patented, 
synthetic molecule with a broad spectrum of activity against bacteria, viruses and fungi.  

Avenova 

Prescription Avenova (0.01% Neutrox) is well-suited for daily eyelid and eyelash hygiene by approximately 30 million 
Americans who suffer from blepharitis and dry eye. Additionally, we estimate that an additional 11 million patients suffering 
from other conditions could potentially benefit from the use of Avenova, bringing the total potential market to approximately 
41 million patients.  

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We  are  targeting  a  customer  base  of  prescribers  that  includes  the  approximately  17,000  ophthalmologists  and 
approximately 37,000 optometrists in the U.S. In August 2014, we launched a dedicated Avenova sales force of 10 direct 
medical sales representatives in 10 major metropolitan areas across the United States. This sales and marketing campaign 
initially targeted major urban areas where large numbers of individuals suffer from problems with their eyelids and lashes. 
These markets included New York, Los Angeles, Boston, Atlanta, and San Francisco. 

Based on positive sales performance, we expanded our sales force to 35 direct medical sales representatives in February 
2015 and to 43 direct medical sales representatives in August 2015. The sales representatives recruited for this effort have 
extensive experience with eye care products and medical devices—a skill set critical for rapid adoption of Avenova. Based 
on extensive market research, we have assigned our sales representatives to the markets across the U.S. representing the 
highest sales potential. These direct medical sales representatives are calling on targeted ophthalmologists and optometrists 
in those markets. These targeted doctors treat large numbers of blepharitis and dry eye patients. Avenova is a natural addition 
to their existing lid hygiene regimens.  

We have distribution agreements with McKesson Corporation, Cardinal Health and AmerisourceBergen Corporation 
that make Avenova accessible in 90% of the approximate 67,000 retail pharmacies across the U.S. Avenova also is marketed 
through the top ophthalmology and optometry networks. These include Vision Source Independent Optometry Network, the 
largest  independent optometry  network  in the  country  representing 2,800  independent  optometrist  offices,  and ALLDocs 
Optometry Group (also known as The Association of LensCrafters Leaseholding Doctors), the second largest independent 
optometry group in the U.S., which works closely with its LensCrafters partners. Through a partnership with ALPHAEON, 
Avenova  is  available  to  member  ophthalmologists  on  the  ShoutMD®  Store,  the  first  social  commerce  store  for  lifestyle 
healthcare products. Avenova is also available for order online with a prescription, and we provide an online pharmacy locator 
to assist patients with filling prescriptions.  

We expect that our prescription business will be the main driver of long-term Avenova sales growth. Reimbursement 
under insurance coverage continues to grow with 68% of Avenova prescriptions covered by insurance plans at the end of 
2015.  Supported  by  the  high  percentage  rate  of  insurance  reimbursement,  we  are  focusing  our  primary  sales  efforts  on 
building our prescription business under a new value pricing model. We are working to improve insurance reimbursement 
coverage for Avenova and aligning our product pricing accordingly. 

Although we are focusing on our prescription sales, we expect continued growth in the doctor to patient direct sales 
channel. We also expect to invest in systems that support prescribing physicians’ efforts to educate their patients. We have 
made it easy for doctors to get Avenova into the hands of patients by providing availability through well-known national 
pharmacy chains, specialty pharmacies, or directly through the practitioners’ office. Furthermore, in order to ensure consistent 
pricing, we have instituted rebate cards to ensure the best price for the patient at the pharmacy. This sales model combined 
with the prospect for further increases in reimbursement under insurance plans has the potential to provide us with additional 
revenue upside.  

Partnerships to Monetize Other Assets 

We  intend  to  seek  additional  sources  of  revenue  and  reduce  expenses  by  licensing  or  selling  select  non-core  assets, 

possibly including intelli-Case, NeutroPhase, CelleRx and our Aganocide compounds, including auriclosene. 

Currently, the program with the most potential is our urology program. Statistically-significant and clinically-meaningful 
results from a Phase 2 clinical study of our Auriclosene Irrigation Solution (AIS) used to reduce urinary catheter blockage 
and encrustation (UCBE), were announced in September 2013. This study, comparing AIS to saline solution, achieved its 
primary endpoints and showed clear benefits for patients with long-term indwelling catheters. We initiated the next Phase 2 
study in the fourth quarter of 2014 at and in the fourth quarter of 2015 announced completion of that study. Patients with 
long-term indwelling urinary catheters were treated with AIS or its Vehicle. The results of this more demanding study showed 
that AIS was better than its Vehicle in preventing the reduction of flow through catheters due to encrustation, the primary 
efficacy measure, by a statistically-significant margin. Furthermore, there were no cases of clinical catheter blockage in the 
AIS arm of the study; all cases of clinical blockage requiring catheter removal occurred only in the Vehicle arm. 

NovaClear intelli-Case 

In June 2015, we received FDA-clearance for the NovaClear intelli-Case, a highly innovative, easy-to-use device for use 
with hydrogen peroxide disinfection solutions for soft and rigid gas permeable contact lenses. The intelli-Case monitors the 
neutralization of hydrogen peroxide during the disinfection cycle with sophisticated microprocessor electronics embedded in 
the cap of what otherwise looks like a standard peroxide lens case. The LED indicators on the lid inform the user if the lenses 
are safe to insert into the eyes, resulting in a disinfection system that is safe yet simple to use. We are seeking potential 

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partners with the resources to make this break-through device available to the largest number of contact lens wearers as soon 
as possible.  

Additional Neutrox-based Products 

In addition to Avenova, the Neutrox branded products currently being commercialized as prescription medical devices 

are NeutroPhase and CelleRx.  

NeutroPhase  (Wound  Care).  Since  its  launch  in  the  U.S.  in  2013,  NeutroPhase  has  impacted  how  wound  care  is 
administered. Consisting of 0.03% Neutrox, NeutroPhase is used to cleanse and remove microorganisms from any type of 
acute or chronic wound, and can be used with any type of wound care modality. Recently, NeutroPhase has been found to be 
an effective irrigation solution as part of the adjunct treatment for Necrotizing Fasciitis (“NF”). Also known as flesh-eating 
disease, NF typically has a high mortality and amputation rate (30% and 70%, respectively) even with aggressive debridement 
and antibiotic treatment. We believe that NeutroPhase is also well-suited to treat the six million patients in the U.S. who 
suffer from chronic non-healing wounds, such as pressure, venous stasis and diabetic ulcers.  

In the U.S. and internationally, NeutroPhase is distributed through commercial partners. In January 2012, we entered 
into an exclusive distribution agreement with Pioneer Pharma Company Limited, or “Pioneer,” a Shanghai-based company, 
for the distribution of NeutroPhase throughout Southeast Asia and mainland China. We subsequently expanded the agreement 
with Pioneer so that it includes the licensing rights to CelleRx and Avenova. In September 2014, China’s Food and Drug 
Administration cleared our NeutroPhase Skin and Wound Cleanser for sale throughout mainland China. In November 2014, 
Taiwan’s Food and Drug Administration cleared our NeutroPhase Skin and Wound Cleanser for sale in Taiwan. We began 
shipping NeutroPhase to China and Taiwan in the fourth quarter of 2014 to support our launch of NeutroPhase Skin and 
Wound  Cleanser  by  Pioneer.  In  the  U.S.,  NeutroPhase  is  distributed  through  our  partner,  Principle  Business  Enterprise 
(“PBE”). 

CelleRx (Dermatology). Created for cosmetic procedures, CelleRx™ (0.015% Neutrox) is a gentle cleansing solution 
that is effective for post-laser resurfacing, chemical peels and other cosmetic surgery procedures. Cosmetic surgeons and 
aesthetic dermatologists have found that CelleRx results in less pain, erythema, and exudate compared to Dakin solution, 
which  contains  bleach  impurities.  CelleRx  is  a  non-alcohol  formulation  that  doesn’t  dry  or  stain  the  skin,  and  most 
importantly, has been shown to reduce the patient’s downtime post procedure.  

Critical Accounting Policies and Estimates  

Our consolidated financial statements have been prepared in accordance with generally accepted accounting principles 
in the United States. The preparation of these consolidated financial statements requires us to make estimates, assumptions 
and judgments that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities 
at the date of the financial statements, as well as the reported revenues and expenses during the reporting periods. In preparing 
these consolidated financial statements, management has made its best estimates and judgments of certain amounts, giving 
due  consideration  to  materiality.  On  an  ongoing  basis,  we  evaluate  our  estimates  and  judgments  related  to  revenue 
recognition, research and development costs, patent costs, stock-based compensation, income taxes and other contingencies. 
We  base  our  estimates  on  historical  experience  and  on  various  other  factors  that  we  believe  are  reasonable  under  the 
circumstances. Actual results may differ from these estimates. 

While  our  significant  accounting policies are  more  fully  described  in Note  2 of  the Notes  to  Consolidated  Financial 
Statements  (Summary  of  Significant  Accounting  Policies),  included  in  Part  II,  Item  8  of  this  report,  we  believe  that  the 
following accounting policies are most critical to fully understanding and evaluating our reported financial results. 

Allowance for Doubtful Accounts 

We charge Bad Debt expense and setup an Allowance for Doubtful Accounts when management believes is unlikely 
specific invoices will be collected. Management identified amounts due that are in dispute and it believes are unlikely to be 
collected at the end of 2015. At December 31, 2015, management had reserved $40 thousand, primarily based on specific 
amounts that are in dispute and are over 120 days past due. 

Inventory 

Inventory is comprised of (1) raw materials and supplies, such as bottles, packaging materials, labels, boxes, pumps; (2) 
goods in progress, which are normally unlabeled bottles; and (3) finished goods. We utilize contract manufacturers to produce 
our products and the cost associated with manufacturing is included in inventory. 

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Inventory is stated at the lower of cost or market value determined by the first-in, first-out method. 

Revenue Recognition 

We sell products through a limited number of distributors and via our webstore. We generally record product sales upon 
shipment to the final customer for our webstore sales and upon shipment from our distributor to the final customers for our 
major distribution partners. 

We recognize product revenue when: (i) persuasive evidence that an arrangement exists, (ii) delivery has occurred and 
title  has  passed, (iii)  the  price  is  fixed  or determinable,  and  (iv) collectability  is  reasonably  assured.  Revenue  from  sales 
transactions where the customer has the right to return the product is recognized at the time of sale only if: (i) our price to the 
customer is substantially fixed or determinable at the date of sale, (ii) the customer has paid us, or the customer is obligated 
to pay us and the obligation is not contingent on resale of the product, (iii) the customer's obligation to us would not be 
changed in the event of theft or physical destruction or damage of the product, (iv) the customer acquiring the product for 
resale  has  economic  substance  apart  from  that  provided  by  us,  (v)  we  do  not  have  significant  obligations  for  future 
performance  to  directly  bring  about  resale  of  the  product  by  the  customer,  and  (vi)  the  amount  of  future  returns  can  be 
reasonably estimated.  

Product Revenue Allowances  

Product revenue is recognized net of cash consideration paid to our customers and wholesalers, for services rendered by 
the wholesalers accordance with the wholesalers agreements, and include a fixed rate per prescription shipped and monthly 
program management and data fees. These services are not deemed sufficiently separable from the customers' purchase of 
the product; therefore, they are recorded as a reduction of revenue at the time of revenue recognition.  

Other  product  revenue  allowances  include  certain  prompt  pay  discounts  and  allowances  offered  to  our  customers, 
program rebates and chargebacks. These product revenue allowances are recognized as a reduction of revenue or as a selling 
expense at the later of the date at which the related revenue is recognized or the date at which the allowance is offered.  

Other Revenue 

License and collaboration revenue is primarily generated through agreements with strategic partners for the development 
and commercialization of our product candidates. The terms of the agreements typically include non-refundable upfront fees, 
funding of research and development activities, payments based upon achievement of certain milestones and royalties on net 
product sales. In accordance with authoritative guidance, we analyze our multiple element arrangements to determine whether 
the elements can be separated. We perform our analysis at the inception of the arrangement and as each product or service is 
delivered. If a product or service is not separable, the combined deliverables are accounted for as a single unit of accounting 
and revenue is recognized over the performance obligation period. Revenue is recognized when the following criteria have 
been met: persuasive evidence of an arrangement exists; delivery has occurred and risk of loss has passed; the seller’s price 
to  the buyer  is  fixed  or determinable;  and  collectability  is  reasonably  assured. If  these  factors  were  to  vary  the resulting 
change could have a material effect on our revenue recognition and on our results of operations. 

Cost of Goods Sold 

Cost of goods sold includes third party manufacturing costs, shipping costs, and other costs of goods sold. Cost of goods 
sold also includes any necessary allowances for excess inventory that may expire and become unsalable. We did record an 
allowance for obsolete inventory of $45 thousand during 2015, but did not record an allowance for excess inventory as of 
December 31, 2015.  

Research and Development Costs 

We charge research and development costs to expense as incurred. These costs include salaries and benefits for research 
and development personnel, costs associated with clinical trials managed by contract research organizations, and other costs 
associated with research, development and regulatory activities. Research and development costs may vary depending on the 
type of item or service incurred, location of performance or production, or lack of availability of the item or service, and 
specificity  required  in  production  for  certain  compounds.  We  use  external  service  providers  to  conduct  clinical  trials,  to 
manufacture  supplies  of  product  candidates  and  to  provide  various  other  research  and  development-related  products  and 
services. Our research, clinical and development activities are often performed under agreements we enter into with external 
service providers.  We estimate and accrue the costs incurred under these agreements based on factors such as milestones 
achieved, patient enrollment, estimates of work performed, and historical data for similar arrangements.  As actual costs are 

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incurred,  we  adjust  our  accruals.    Historically,  our  accruals  have  been  consistent  with  management’s  estimates,  and  no 
material adjustments to research and development expenses have been recognized.  Subsequent changes in estimates may 
result in a material change in our expenses, which could also materially affect our results of operations. 

Stock-Based Compensation 

Stock-based compensation expense is measured at the grant date for all stock-based awards to employees and directors 
and is recognized as expense over the requisite service period, which is generally the vesting period. Forfeitures are estimated 
at the time of grant and reduce compensation expense ratably over the vesting period. This estimate is adjusted periodically 
based on the extent to which actual forfeitures differ, or are expected to differ, from the previous estimate. See Note 10 of 
the Notes to Consolidated Financial Statements for further information regarding stock-based compensation expense and the 
assumptions used in estimating that expense. For stock options granted to employees, the fair value of the stock options is 
estimated using a Black-Scholes-Merton option pricing model.  

Stock-based compensation arrangements with non-employees are recorded at their fair value on the measurement date. 
The measurement of stock-based compensation is subject to periodic adjustment as the underlying equity instruments vest. 
Non-employee stock-based compensation charges are amortized over the vesting period on a straight-line basis. For stock 
options  granted  to  non-employees,  the  fair  value  of  the  stock  options  is  estimated  using  a  Black-Scholes-Merton  option 
pricing model. 

Income Taxes 

We account for income taxes under the asset and liability method. Deferred tax assets and liabilities are recognized for 
the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets 
and liabilities and their respective tax bases and operating loss and tax credit carryforwards. Deferred tax assets and liabilities 
are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences 
are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized 
in income in the period that includes the enactment date. A valuation allowance is recognized if it is more likely than not that 
some portion or the entire deferred tax asset will not be recognized.  

Common Stock Warrant Liabilities 

For warrants that are issued or modified and there is a deemed possibility that we may have to settle them in cash, or for 
warrants we issue or modify that contain an exercise price adjustment feature that reduces the exercise price and increases 
the  number  of  shares  of  our  common  stock  eligible  for  purchase  thereunder  in  the  event  we  subsequently  issue  equity 
instruments at a price lower than the exercise price of the warrants, we record the fair value of the issued or modified warrants 
as  a  liability  at  each balance  sheet date  and record  changes  in the  estimated  fair value  as  a non-cash gain  or  loss  on  the 
consolidated statements of operations and comprehensive loss. The fair values of these warrants have been determined using 
the Binomial Lattice (“Lattice”) valuation model, and the change in the fair value are recorded in the consolidated statements 
of operations and comprehensive gain or loss. The Lattice model provides for assumptions regarding volatility, call and put 
features and risk-free interest rates within the total period to maturity. These values are subject to a significant degree of our 
judgment.   

Recent Accounting Pronouncements 

See Note 2 of the Notes to Consolidated Financial Statements (Summary of Significant Accounting Policies) included 

in Part II, Item 8 of this report for information on recent accounting pronouncements. 

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Results of Operations 

Comparison of Years Ended December 31, 2015, 2014 and 2013 

Twelve Months Ended December 31, 

%  
Change 

%  
Change 

2015 

2014 
(in thousands, except per share data) 

2013 

Statements of Operations Data: 
Sales: 

Product Revenue, net ........................................   $ 
Other Revenue ..................................................     
Total Net Sales .....................................................     

Product Cost of Goods Sold ..........................     
Gross Profit ..........................................................     

4,146      
235      
4,381      

1,261      
3,120      

Operating expenses: 

Research and development ...............................     
Selling, general and administrative ...................     
Total operating expenses ......................................     
Operating loss.......................................................     
Non-cash gain (loss) on change in fair value of 

warrants ..........................................................     
Other income (expense), net .................................     
Loss before income taxes .....................................     
Provision for income taxes ...................................     

6,045      
18,089      
24,134      
(21,014)     

2,149      
(96)     
(18,961)     
(12)     

506     $
(36)     

159       
449       

(36)     
128       
38       
25       

29       
(536)     
25       
500       

684       
370       
1,054       

486       
568       

9,511       
7,935       
17,446       
(16,878)     

1,664       
22       
(15,192)     
(2)     

207     $
(89)     

200       
(83)     

(24)     
25       
(7)     
9       

(400)     
2,100       
(5)     
-      

223   
3,254   
3,477   

162   
3,315   

12,461   
6,340   
18,801   
(15,486) 

(555) 
1   
(16,040) 
(2) 

Net loss  ................................................................   $ 

(18,973)     

25     $

(15,194)     

(5)   $

(16,042) 

Total Net Sales and Gross Profit 

Total Net Sales were $4,381 thousand for the year ended December 31, 2015, compared to $1,054 thousand for the year 

ended December 31, 2014, and $3,477 thousand for the year ended December 31, 2013. 

Gross Profit was $3,120 thousand for the year ended December 31, 2015, compared to $568 thousand for the year ended 

December 31, 2014, and $3,315 thousand for the year ended December 31, 2013. 

2015-2014 

Product revenue increased by $3,462 thousand, or 506%, to $4,146 thousand from $684 thousand and other revenue 
decreased by $135 thousand, or 36%, to $235 thousand from $370 thousand for the year ended December 31, 2015, compared 
to  the  year  ended  December  31,  2014.  The  change  in  the  product  revenue  was  primarily  the  result  of  increased  sales  of 
Avenova in connection with the focus on product commercialization, partially offset by a reduction in other revenue because 
of our de-emphasis of technology and collaboration agreements.  

Gross  Profit  increased  by  $2,552  thousand,  or  449%,  to  $3,120  thousand  from  $568  thousand  for  the  year  ended 
December 31, 2015, compared to the year ended December 31, 2014. The increase in Gross Profit was primarily the result 
of increased sales of Avenova. 

2014-2013 

Product revenue increased $461 thousand, or 207%, to $684 thousand from $223 thousand and other revenue decreased 
by $2,884 thousand, or 89%, to $370 from $3,254 thousand for the year ended December 31, 2015, compared to the year 
ended  December  31,  2014.  The  change  in  product  revenue  was  primarily  the  result  of  increased  sales  of  Avenova.  The 
decrease in 2014 other revenue was primarily related to the full recognition of the upfront payments from a collaboration 
agreement in 2013. 

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Gross Profit decreased by $2,747 thousand, or 83%, to $568 thousand from $3,315 thousand for the year ended December 
31, 2014, compared to the year ended December 31, 2013. The reduction in Gross Profit was primarily related to the full 
recognition of the upfront payments from a collaboration agreement in 2013. 

Research and Development 

Total Research and Development expenses were $6,045 thousand, $9,511 thousand, and $12,461 thousand for the years 

ended December 31, 2015, December 31, 2014, and December 31, 2013, respectively. 

2015-2014 

Research  and Development expenses decreased by $3,466  thousand, or  36%,  to $6,045  thousand  for  the  year  ended 
December 31, 2014, from $9,511 thousand for the year ended December 31, 2014. The reduction is primarily the result of 
reduced spending on clinical trials and shifting responsibilities to production support from research and development. 

2014-2013 

Research  and  Development  expenses  decreased  $2,950  thousand,  or  24%,  to  $9,511  thousand  for  the  year  ended 
December 31, 2014, from $12,461 thousand for the year ended December 31, 2013. The decrease is primarily the result of 
fewer in-clinical activities as we completed our BAYnovation trial for viral conjunctivitis and neared the completion of the 
BACTOvation trial for bacterial conjunctivitis. 

Sales, general and administrative 

Sales, general and administrative expenses were $18,089 thousand, $7,935 thousand, and $6,340 thousand for the years 
ended December 31, 2015, December 31, 2014, and December 31, 2013, respectively. We expect to incur increasing sales, 
general  and  administrative  expenses  throughout  2016  and  in  subsequent  years  as  we  support  the  commercialization  of 
Avenova. 

2015-2014 

Sales, general and administrative expenses increased by $10,154 thousand, or 128%, to $18,089 thousand for the year 
ended December 31, 2015, from $7,935 thousand for the year ended December 31, 2014. The increase was primarily due to 
the increase in sales representative headcount and sales and marketing activities for the launch of Avenova, which began in 
August of 2014. 

2014-2013 

Sales, general and administrative expenses increased by $1,595 thousand, or 25%, to $7,935 thousand for the year ended 
December 31, 2104, from $6,340 thousand for the year ended December 31, 2013. The increase was primarily due to the 
increase  in  sales  representative  headcount  and  sales  and  marketing  activities  for  the  launch  of  Avenova,  which  began  in 
August of 2014. 

Non-cash gain (loss) on changes in fair value of warrants 

The  adjustments  to  the  fair  value  of  warrants  were  gains  of  $2,149  thousand,  $1,664  thousand,  and  a  loss  of  $555 

thousand for the years ended December 31, 2015, December 31, 2014, and December 31, 2013, respectively. 

2015-2014 

The non-cash gain on changes in the fair value of warrants relates primarily to warrants issued or modified as part of the 
October 2015 financing. The change in fair value was primarily the result of two factors. First, the October 2015 financing 
included the following elements that increased the fair value of the warrant liability: the term of the warrants issued in July 
2011 was extended and the exercise price adjusted to the then market price, the terms of the warrants issued in March 2015 
were similarly adjusted, which caused the March 2015 warrants to be reclassified from equity to a liability, and additional 
warrants were issued as part of the October 2015 financing. The October 2015 warrants were classified as a liability when 
they were issued. Second, the warrants issued in July 2011, March 2015 and October 2015 were all valued when they were 
issued and re-measured as of December 31, 2015, the result being a reduction in the warrant liability of $2,149 thousand. 
Please see Note 8 of the Financial Statements for a more complete explanation. 

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2014-2013 

The non-cash gain on changes in fair value of warrants relates primarily to the warrants issued in July 2011. The balance 

fluctuated primarily with our stock price and the remaining term of the warrants.  

Other income (expense), net 

Other income (expense), net, were expense of $96 thousand and income of $22 thousand and $1 thousand for the years 
ended December 31, 2015, December 31, 2014, and December 31, 2013, respectively. The change is primarily the result of 
converting  investments  in  securities  to  operating  cash  during  2015,  instead  of  being  invested  in  accounts  that  generated 
returns. 

Net loss 

The Net loss was $18,973 thousand, $15,194 thousand, and $16,042 thousand for the years ended December 31 2015, 

December 31, 2014, and December 31, 2013, respectively. 

2015-2014 

Net loss increased by $3,779 thousand, or 25%, to $18,973 thousand for the year ended December 31, 2015, from $15,194 
thousand  for  the  year  ended  December  31,  2014.  This  increase  was  primarily  the  result  of  greater  Selling,  general  and 
administrative expenses associated with the commercialization of Avenova, which were partially offset by increased Product 
Revenue and Gross Profit and reduced Research and Development expenses. 

2014-2013 

Net loss decreased by $848 thousand, or 5%, to $15,194 thousand for the year ended December 31, 2014, from $16,042 
thousand for the year ended December 31, 2013. The decrease in Net loss was primarily related to our efforts to focus on the 
commercialization of products and to de-emphasize our research and development programs. 

Liquidity and Capital Resources 

As of December 31, 2015, we had cash and cash equivalents of $2.4 million, compared to $5.4 million and $13.1 million 
at  December  31,  2014  and  2013,  respectively.  We  have  incurred  cumulative  net  losses  of  $90.5  million  since  inception 
through December 31, 2015. Since inception, we have funded our operations primarily through the sales of our stock and 
warrants and funds received under our collaboration agreements. Since December 31, 2014, we have raised net proceeds of 
$1.2 million related to sales of our stock through the At-the-Market Offering Agreement (“ATM Agreement”) set up in 2014. 
In 2015, we closed three additional financings in which we raised a total of $13.0 million, or approximately $11.5 million in 
net  cash  proceeds  after  deducting  underwriting  commissions  and  other  offering  costs  of  $1.5  million.  We  also  raised 
approximately $1.3 million on the sale of warrants. Additionally, in December 2015, we borrowed $1.7 million, the first 
tranche of an aggregate $3.0 million bridge loan.  

Although we recently raised capital, our cash and our cash equivalents are not sufficient to fund our planned operations. 
To  achieve  this,  we  will  continue  with  our  historical  financing  strategy  to  raise  additional  capital  in  order  to  fund  our 
operations  and  meet  our  ongoing  obligations,  with  the  goal  of  being  cash  flow  positive  by  December  2016.  There  is  no 
assurance  that  we  will  be  able  to  raise  capital,  or  if  we  are  able  to  raise  capital,  that  it  will  be  on  favorable  terms.  We 
incorporated additional information regarding risks related to our capital and liquidity in Item 1A. Risk Factors of this report, 
which should be read with this disclosure. 

Until we can generate sufficient product revenue, we expect to finance future cash flow needs through public or private 
equity  offerings,  debt  financings  or  corporate  collaboration  and  licensing  arrangements.  In  addition,  we  are  seeking  to 
monetize  non-core  assets  such  as  our  UCBE  program.  In  two  Phase  2  clinical  studies,  our  AIS  demonstrated  clinically 
meaningful and statistically significant results in preventing encrustation and incidence of clinical blockage in the in-dwelling 
catheters of chronically catheterized patients. To the extent that we raise additional funds by issuing equity securities, our 
shareholders may  experience  dilution.  In  addition, debt  financing,  if  available,  may  involve restrictive  covenants.  To  the 
extent that we raise additional funds through collaboration and licensing arrangements, it may be necessary to relinquish 
some rights to our technologies or product candidates, or grant licenses on terms that are not favorable to us. We are currently 
seeking  partners/purchasers  who  would  pay  an  up-front  fee  for  some  of  our  “non-core  assets,”  such  as  our  urology  and 
aesthetic dermatology programs.  

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Cash Used in Operating Activities 

For the year ended December 31, 2015, cash used in operating activities was $18.6 million compared to $15.0 million 
for the year ended December 31, 2014. The increase in 2015 of cash used in operating activities was due to increased spending 
on sales and marketing activities in the amount of $8.9 million, partially offset by a decrease in spending on clinical activity 
in 2015 in the amount of $1.8 million, as we were reaching completion of certain clinical trials. 

For the year ended December 31, 2014, cash used in operating activities was $15.1 million compared to $13.0 million 
for the year ended December 31, 2013. The increase in 2014 of cash used in operating activities was due to spending on sales 
and  marketing  activities  for  the  launch  of  Avenova,  which  we  started  in  August  2014,  partially  offset  by  a  decrease  in 
spending on clinical activity in 2014, as we were reaching completion of certain clinical trials. 

Cash Provided By or Used In Investing Activities 

For the year ended December 31, 2015, $0.1 million cash was used in investing activities, and in December 31, 2014 
and 2013, cash provided by investing activities of $2.6 million, and $1.4 million, respectively, was primarily attributable to 
the net effects of purchases of short-term investments and sales and maturities. 

Cash Provided by Financing Activities 

Net  cash  provided  by  financing  activities  of  $15.6  million  for  the  year  ended  December  31,  2015,  was  primarily 
attributable to proceeds from the sale of common stock and warrants in March, May and October, the sale of our common 
stock under our ATM agreement and the proceeds from the December bridge loan. 

Net  cash  provided  by  financing  activities  of  $7.4  million  for  the  year  ended  December  31,  2014,  was  primarily 
attributable to proceeds from the sale of our common stock under our ATM agreement and the sale of common stock and 
warrants in our March financing. 

Net  cash  provided  by  financing  activities  of  $9.3  million  for  the  year  ended  December  31,  2013,  was  primarily 
attributable to the $5.7 million provided by stock sales to Pioneer, $375 thousand in stock sales to another investor and $2.9 
million provided by exercises of warrants and stock options. 

28 

 
  
    
  
  
  
  
  
  
  
 
 
Quarterly Results of Operations (unaudited)  

The following table presents unaudited quarterly results of operations for the eight most recent quarters ending with the 
quarter ended December 31, 2015. This information has been derived from our unaudited consolidated financial statements 
and has been prepared by us on a basis consistent with our audited annual consolidated financial statements and includes all 
adjustments, consisting only of normal recurring adjustments, which management considers necessary for a fair presentation 
of the information for the periods presented. 

Quarter Ended  
   Dec. 31,       Sept. 30,       June 30,      March 31,      Dec. 31,       Sept. 30,       June 30,      March 31,   

2015 

2015 
  (in thousands, except per share data) 

2015 

2015 

2014 

2014 

2014 

2014 

Statements of Operations 

Data: 

Sales: 

Product Revenue ............   $ 
Other Revenue ...............     
Total Net Sales ...................     

1,587     $ 
48       
1,635       

1136    $ 
64      
1,200       

931    $ 
77      
1,008      

492     $ 
46       
538      

385     $ 
106       
491       

90     $ 
62       
152       

21     $ 
102       
123       

Product Cost of 

Goods Sold ..............     
Gross Profit ........................     
Operating expenses: 
Research and development .     
Sales, general and 

administrative ..................     
Total operating expenses ....     
Operating loss ....................     
Non-cash gain (loss) on 
change in fair value of 
warrants ...........................     

Other income (expense), 

net ....................................     
Loss before income taxes ...     
Benefit from (provision 

for) income taxes .............     
Net loss ..............................   $ 
Net loss per share: 
Basic and diluted  ...............   $ 
Shares used in computing 

net loss per share: 
Basic and diluted (after 

effect of 1-for-25 reverse 
stock split) .......................     

591       
1,044       

269       
931      

253      
755      

148      
390      

296       
195       

42       
110       

18       
105       

1,239       

1,920       

1,245      

1,641       

2,433       

2,312       

2,238       

2,528   

5,951       
7,190       
(6,146)     

4,359       
6,279       
(5,348)     

4,369      
5,614      
(4,859)     

3,410       
5,051       
(4,661)     

2,663       
5,096       
(4,901)     

1,911       
4,223       
(4,113)     

1,653       
3,891       
(3,786)     

1,708   
4,236   
(4,078) 

1,976       

139       

—      

34       

451       

(104)     

797       

520   

(32)     
(4,202)     

(31)     
(5,240)     

(22)     
(4,881)     

(11)     
(4,638)     

(26)     
(4,476)     

(2)     
(4,219)     

57       
(2,932)     

(7) 
(3,565) 

2       
(4,204)   $ 

(2)     
(5,242)   $ 

(6)     
(4,887)   $ 

(2)     
(4,640)   $ 

8       
(4,468)   $ 

—      
(4,219)   $ 

(10)     
(2,942)   $ 

—  
(3,565) 

(1.26)   $ 

(1.76)   $ 

(1.84)   $ 

(2.13)   $ 

(2.17)   $ 

(2.08)   $ 

(1.45)   $ 

(1.97) 

3,337      

2,985      

2,653      

2,175      

2,060      

2,033      

2,031      

1,814  

188   
100   
288   

130   
158   

Balance Sheet Data: 
Cash, cash equivalents and short-term investments ......   $ 
Working capital .............................................................     
Total assets ....................................................................     
Equipment loan—current and non-current ....................     
Deferred revenue—current and non-current .................     
Common stock and additional paid-in capital ...............     
Total stockholders’ equity (deficit) ...............................     

2015 

2014 

2013 
(in thousands) 

2012 

2011 

2,385     $ 
(106)     
5,077       
—       
2,418       
85,422       
(5,098)      

5,429    $ 
3,607      
7,537      
—      
2,425      
73,395      
1,848      

13,053    $ 
11,163      
15,650      
—      
1,871      
64,884      
8,516      

16,870    $ 
15,108      
19,235      
—      
1,892      
54,373      
14,049      

14,138  
11,720  
15,963  
—  
2,250  
42,672  
9,344  

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Net Operating Losses and Tax Credit Carryforwards  

As of December 31, 2015, we had net operating loss carryforwards for federal and state income tax purposes of $80.6 
million  and  $77.1  million,  respectively.  If  not  utilized,  the  federal  and  state  net  operating  loss  carryforwards  will  begin 
expiring at various dates between 2024 and 2035. As of December 31, 2015, we also had tax credit carryforwards for federal 
income tax purposes of $1,274,000 and $256,000 for state tax purposes.  

Current  federal  and  California  tax  laws  include  substantial  restrictions  on  the  utilization  of  net  operating  loss 
carryforwards in the event of an ownership change of a corporation. Accordingly, our ability to utilize net operating loss 
carryforwards  may  be  limited  as  a  result  of  such  ownership  changes.  Such  a  limitation  could  result  in  the  expiration  of 
carryforwards before they are utilized.  

Inflation and Seasonality 

We  do  not  believe  that  inflation  has  had  a  material  impact  on  our  business  and  operating  results  during  the  periods 
presented, and we do not expect it to have a material impact in the near future, although there can be no assurances that our 
business will not be affected by inflation in the future. 

We do not believe our business is subject to seasonality or any other cyclical trends. 

Off-Balance Sheet Arrangements  

We have no off-balance sheet arrangements as of December 31, 2015. 

Contractual Obligations 

Our contractual cash commitments as of December 31, 2015, were as follows (in thousands): 

Contractual Obligations 
Operating leases ................................   $ 
  $ 

Total 

Less than  
1 year 

     1 - 3 years 

     3 - 5 years 

More than  
5 years 

3,290     $ 
3,290     $ 

643    $ 
643    $ 

1,344     $ 
1,344     $ 

1,303    $ 
1,303    $ 

-  
-  

This compares to contractual cash commitments as of December 31, 2014, of $3.9 million. 

Our commitments under the operating leases shown above consist of payments relating to our lease of laboratory and 

office space in one office building in Emeryville, California. This lease expires on October 31, 2020. 

ITEM 7A.  QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK 

Our market risk consists principally of interest rate risk on our cash, cash equivalents, and short-term investments. Our 
exposure  to  market  risk  is  limited  primarily  to  interest  income  sensitivity,  which  is  affected by  changes  in  interest rates, 
particularly because the majority of our investments are in short-term debt securities. 

Our investment policy restricts our investments to high-quality investments and limits the amounts invested with any 
one issuer, industry, or geographic area. The goals of our investment policy are as follows: preservation of capital, assurance 
of liquidity needs, best available return on invested capital, and minimization of capital taxation. Some of the securities in 
which we invest may be subject to market risk. This means that a change in prevailing interest rates may cause the principal 
amount of the investment to fluctuate. For example, if we hold a security that was issued with an interest rate fixed at the 
then-prevailing rate and the prevailing interest rate later rises, the principal amount of our investment will probably decline. 
To minimize this risk, in accordance with our investment policy, we maintain our cash and cash equivalents in short-term 
marketable  securities,  including  money  market  mutual  funds,  Treasury  bills,  Treasury  notes,  certificates  of  deposit, 
commercial paper, and corporate and municipal bonds. The risk associated with fluctuating interest rates is limited to our 
investment portfolio. Due to the short-term nature of our investment portfolio, we believe we have minimal interest rate risk 
arising  from  our  investments.  As  of  December  31,  2015  and  2014,  a  10%  change  in  interest  rates  would  have  had  an 
immaterial effect on the value of our short-term marketable securities. We do not use derivative financial instruments in our 
investment portfolio. We do not hold any instruments for trading purposes. 

With most of our focus on Avenova in the domestic U.S. market, we have not had any material exposure to foreign 

currency rate fluctuations. 

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ITEM 8.  FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA 

The financial statements required by this Item 8 are set forth below. Our quarterly financial information is set forth in 

Item 7 of this report and is hereby incorporated into this Item 8 by reference. 

INDEX TO CONSOLIDATED FINANCIAL STATEMENTS 

    Page 
Report of Independent Registered Public Accounting Firm ...........................................................................................     32 
Consolidated Balance Sheets as of December 31, 2015 and 2014 .................................................................................     33 
Consolidated Statements of Operations and Comprehensive Loss for the Years Ended December 31, 2015, 2014 

and 2013 ..................................................................................................................................................................... 

34 

Consolidated Statements of Stockholders’ Equity (Deficit) for the Years Ended December 31, 2015, 2014  

and 2013 ..................................................................................................................................................................... 

35 
Consolidated Statements of Cash Flows for the Years Ended December 31, 2015, 2014 and 2013 ..............................     36 
Notes to Consolidated Financial Statements ..................................................................................................................     37 

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REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM 

To the Board of Directors and Stockholders of 
NovaBay Pharmaceuticals, Inc. 

We have audited the accompanying consolidated balance sheets of NovaBay Pharmaceuticals, Inc. as of December 31, 2015 
and 2014 and the related consolidated statements of operations and comprehensive loss, stockholders’ equity, and cash flows 
for each of the three years in the period ended December 31, 2015. These financial statements are the responsibility of the 
Company’s management. Our responsibility is to express an opinion on these financial statements based on our audits.  

We  conducted  our  audits  in  accordance  with  the  standards  of  the  Public  Company  Accounting  Oversight  Board  (United 
States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial 
statements are free of material misstatement. The Company is not required to have, nor were we engaged to perform, an audit 
of its internal control over financial reporting. Our audits included consideration of internal control over financial reporting 
as a basis for designing audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an 
opinion on the effectiveness of the Company’s internal control over financial reporting. Accordingly, we express no such 
opinion. An audit also includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial 
statements, assessing the accounting principles used and significant estimates made by management, as well as evaluating 
the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion. 

In our opinion, the consolidated financial statements audited by us present fairly, in all material respects, the consolidated 
financial position of NovaBay Pharmaceuticals, Inc. as of December 31, 2015 and 2014, and the consolidated results of its 
operations and its cash flows for each of the three years in the period ended December 31, 2015, in conformity with accounting 
principles generally accepted in the United States of America. 

The accompanying consolidated financial statements have been prepared assuming that the Company will continue as a going 
concern. As discussed in Note 1 to the consolidated financial statements, the Company has suffered recurring losses and 
negative cash flows from operations and has a stockholders’ deficit, all of which raise substantial doubt about its ability to 
continue as a going concern. The consolidated financial statements do not include any adjustments that might result from the 
outcome of this uncertainty. 

San Francisco, California 
March 3, 2016 

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NOVABAY PHARMACEUTICALS, INC. 
CONSOLIDATED BALANCE SHEETS 
(in thousands, except shares and per share data) 

ASSETS 

Current assets: 

Cash and cash equivalents .................................................................................   $
Accounts receivable, net of allowance for doubtful accounts ($40 and $0 at 

December 31 2015, and December 31, 2014, respectively) ............................     
Inventory, net .....................................................................................................     
Prepaid expenses and other current assets .........................................................     
Total current assets ............................................................................................     
Property and equipment, net  ....................................................................................     
Other assets ...............................................................................................................     
TOTAL ASSETS ......................................................................................................   $

LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT) 
Liabilities: 

Current liabilities: 

Accounts payable ...............................................................................................   $
Accrued liabilities  .............................................................................................     
Deferred revenue ................................................................................................     
Total current liabilities .......................................................................................     
Deferred revenues - non-current ...............................................................................     
Deferred rent .............................................................................................................     
Notes payable, related party ......................................................................................     
Warrant liability ........................................................................................................     
Total liabilities ...................................................................................................     

Commitments and contingencies (Note 7) 
Stockholders' equity (deficit): 

December 31, 

2015 

2014 

2,385     $

536       
1,345       
261       
4,527       
395       
155       
5,077     $

2,483     $
1,980       
170       
4,633       
2,248       
189       
1,655       
1,450       
10,175       

5,429   

273   
521   
729   
6,952   
436   
149   
7,537   

1,865   
1,055   
425   
3,345   
2,000   
171   
—  
173   
5,689   

Preferred stock: 5,000 shares authorized; none outstanding at December 31, 2015 

and 2014 .................................................................................................................     

—       

—  

Common stock, $0.01 par value; 240,000 shares authorized; 3,486 and 2,066 

shares issued and outstanding at December 31, 2015 and 2014, respectively ........     
Additional paid-in capital ..........................................................................................     
Accumulated other comprehensive loss ....................................................................     
Accumulated deficit ..................................................................................................     
Total stockholders' equity (deficit) ....................................................................     
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT) ................   $

35       
85,387       
—       
(90,520 )     
(5,098 )     
5,077     $

21  
73,374  
—  
(71,547) 
1,848   
7,537   

The accompanying notes are an integral part of these consolidated financial statements 

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NOVABAY PHARMACEUTICALS, INC. 
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS 
(in thousands, except per share data) 

Year Ended December 31, 
2014 

2015 

2013 

Sales: 

Product Revenue, net ......................................................................   $ 
Other Revenue ................................................................................     
Total Sales, net ...................................................................................     

Product Cost of Goods Sold ........................................................     
Gross Profit ........................................................................................     

Research and development ..........................................................     
Sales, general and administrative ................................................     
Total Operating Expenses ...........................................................     
Operating Loss ...................................................................................     

Non cash gain(loss) on changes in fair value of warrants ..................     
Other income (expense), net ...............................................................     

Loss before provision for income taxes .............................................     
Provision for income tax ....................................................................     
Net loss ...............................................................................................     

4,146     $
235       
4,381       

1,261       
3,120       

6,045       
18,089       
24,134       
(21,014)     

2,149       
(96)     

(18,961)     
(12)     
(18,973)     

Change in Unrealized gains (losses) on available for sale securities .     
Comprehensive loss ...........................................................................   $ 

—      
(18,973)   $

684     $
370       
1,054       

486       
568       

9,511       
7,935       
17,446       
(16,878 )     

1,664       
22       

(15,192 )     
(2 )     
(15,194 )     

15       
(15,179 )   $

223   
3,254   
3,477   

162   
3,315   

12,461   
6,340   
18,801   
(15,486 ) 

(555 ) 
1   

(16,040 ) 
(2 ) 
(16,042 ) 

(2 ) 
(16,044 ) 

Loss per share (basic and diluted) ......................................................   $ 

(6.82)   $

(7.65 )   $

(10.51 ) 

Basic and Diluted Shares used in loss per share calculation ..............     

2,784       

1,985       

1,527   

The accompanying notes are an integral part of these consolidated financial statements 

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NOVABAY PHARMACEUTICALS, INC. 
CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY (DEFICIT) 
(in thousands) 

     Accumulated 

    Additional     

Other  

Total  

Balance at December 31, 2012  ........................       1,477     $ 
Net loss ..........................................................       —       

15    $ 
—      

Change in unrealized gains (losses) on 

   Common Stock       Paid-In 
  Shares     Amount      Capital 

Loss 

    Comprehensive      Accumulated      Stockholders'     
    Equity (Deficit)   
14,049   
(16,042) 

(40,311)   $ 
(16,042)     

(13)   $ 
—      

     Deficit  

54,358    $ 
—      

investments ..........................................      —       

—      

—      

Issuance of common stock in connection 

12       
with shelf offering, net of offering costs ......      
200       
Issuance of stock to Pioneer ...............................      
Issuance of stock to Feichter ..........................      
12       
Credits on sales of NeutroPhase .....................       —       
11       
Issuance of stock for option exercises ............      
72       
Issuance of stock for warrant exercises ..........      
Issuance of stock to consultants for services ..      
1       
Stock-based compensation expense related to 

—      
2      
—      
—      
—      
1      
—      

352      
5,698      
375      
7      
126      
2,717      
49      

warrants .......................................................       —       

—      

166      

Stock-based compensation expense related to 

employee and director stock options ...........       —       

—      

921      

Stock-based compensation expense related to 

non-employee stock options ........................       —       
Balance at December 31, 2013  ....................       1,785       
Net loss ..........................................................       —       

Change in unrealized gains (losses) on 

—      
18      
—      

97      
64,866      
—      

investments ..........................................      —       

—      

—      

Issuance of common stock in connection 

with shelf offering, net of offering costs ......      

275       
Issuance of stock to Pioneer ...........................       —       
2       
Issuance of stock for option exercises ............      
2       
Issuance of stock to consultants for services ..      
Employee bonus paid in common stock .........      
1       
Stock-based compensation expense related to 

3      
—      
—      
—      
—      

7,122      
205      
34      
28      
77      

employee and director stock options ...........       —       

—      

853      

Stock-based compensation expense related to 

non-employee stock options ........................       —       
Vesting of employee restricted stock awards .      
1       
Balance at December 31, 2014  ....................       2,066       
Net loss ..........................................................       —       
Issuance of common stock in connection 

—      
—      
21      
—      

189      
—      
73,374      
—      

with shelf offering, net of offering costs ......      

85       

1      

1,176      

Issuance of stock and warrants, net of 

offering costs ...............................................       1,328       
Equity transferred to warrant liability ............       —       
4       
Issuance of stock to consultants for services ..      
Employee bonus paid in common stock .........      
3       
Stock-based compensation expense related to 

13      
—      
—      
—      

11,505      
(2,175)     
63      
62      

employee and director stock options ...........       —       

—      

1,194       

Stock-based compensation expense related to 

(2)     

—      
—      
—      
—      
—      
—      
—      

—      

—      

—      
(15)     
—      

15       

—      
—      
—      
—      
—      

—      

—      
—      
—      
—      

—      

—      
—      
—      
—      

—      

—      

—      
—      
—      
—      
—      
—      
—      

—      

—      

(2) 

352   
5,700   
375   
7   
126   
2,718   
49   

166   

921   

—      
(56,353)     
(15,194)     

97   
8,516   
(15,194) 

—      

—      
—      
—      
—      
—      

—      

—      
—      
(71,547)     
(18,973)     

—      

—      
—      
—      
—      

—      

15   

7,125   
205   
34   
28   
77   

853   

189   
—  
1,848   
(18,973) 

1,177   

11,518  
(2,175) 
63   
62   

1,194   

188   
(5,098) 

non-employee stock options ........................       —       
Balance at December 31, 2015 .....................       3,486     $ 

—      
35    $ 

188       
85,387     $ 

—      
—    $ 

—      
(90,520)   $ 

The accompanying notes are an integral part of these consolidated financial statements. 

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NOVABAY PHARMACEUTICALS, INC. 
CONSOLIDATED STATEMENTS OF CASH FLOWS 
(in thousands) 

Cash flows from operating activities: 
Net loss ...............................................................................................   $
Adjustments to reconcile net loss to net cash used in operating 

activities: 

Depreciation and amortization ...........................................................     
Net realized loss on sales of short-term investments ..........................     
Loss (gain) on disposal of property and equipment ...........................     
Stock-based compensation expense for options and stock issued to 

employees and directors ...................................................................     
Compensation expense for warrants issued for services ....................     
Stock-based compensation expense for options, warrants and stock 

issued to non-employees ..................................................................     
Non-cash (gain) loss on change in fair value of warrants ..................     
Changes in operating assets and liabilities: 
(Increase) decrease in accounts receivable .........................................     
Increase in inventory ..........................................................................     
(Increase) decrease in prepaid expenses and other assets ...................     
Increase (decrease) in accounts payable and accrued liabilities .........     
Increase (decrease) in deferred revenue .............................................     
Net cash used in operating activities ..................................................     
Cash flows from investing activities: 
Purchases of property and equipment ................................................     
Proceeds from disposal of property and equipment ...........................     
Purchases of short-term investments ..................................................     
Proceeds from maturities and sales of short-term investments ..........     
Net cash provided (used) by investing activities ................................     
Cash flows from financing activities: 
Proceeds from common stock issuances, net .....................................     
Proceeds from exercise of options and warrants ................................     
Proceeds from borrowings .................................................................     
Proceeds from shelf offering, net .......................................................     
Net cash provided by financing activities ..........................................     
Net increase (decrease) in cash and cash equivalents .........................     
Cash and cash equivalents, beginning of period ................................     
Cash and cash equivalents, end of period ...........................................   $
Supplemental disclosure of non cash information 
Bonus paid in stock ............................................................................   $
Stock issued to consultants for services .............................................   $
Options exercised ...............................................................................   $
Equity transferred to warrant liability ................................................   $

Year Ended December 31. 
2014 

2013 

2015 

(18,973)   $ 

(15,194)   $ 

(16,042) 

164       
—      
(1)     

1,194       
—      

188       
(2,149)     

(299)     
(751)     
402       
1,655       
11      
(18,559)     

(123)     
37       
—      
—      
(86)     

11,519      
1,250      
1,655       
1,177       
15,601       
(3,044)     
5,429       
2,385     $ 

62     $ 
63     $ 
(4)   $ 
(2,175)   $ 

232       
40       
(54)     

853       
—      

189       
(1,664)     

555       
(451)     
138       
(252)     
553       
(15,055)     

(68)     
128       
(4,012)     
6,550       
2,598       

227       
34       
—      
7,125       
7,386       
(5,071)     
10,500       
5,429     $ 

54     $ 
7     $ 
—    $ 
—    $ 

314  
21  
—  

921  
166  

97  
555  

159  
(208) 
(345) 
1,414  
(21) 
(12,969) 

(141) 
—  
(4,330) 
5,878  
1,407  

6,075  
2,900  
—  
352  
9,327  
(2,235) 
12,735  
10,500  

—  
49  
—  
—  

The accompanying notes are an integral part of these consolidated financial statements. 

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NOVABAY PHARMACEUTICALS, INC. 
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS 

NOTE 1. ORGANIZATION 

NovaBay  Pharmaceuticals,  Inc.  (the  “Company”)  is  a  biopharmaceutical  company  focused  on  commercializing 

prescription Avenova® daily lid and lash hygiene in the domestic eye care market. 

The  Company  was  incorporated  under  the  laws  of  the  State  of  California  on  January  19,  2000,  as  NovaCal 
Pharmaceuticals, Inc. It had no operations until July 1, 2002, on which date it acquired all of the operating assets of NovaCal 
Pharmaceuticals,  LLC,  a  California  limited  liability  company.  In  February  2007,  it  changed  its  name  from  NovaCal 
Pharmaceuticals,  Inc.  to  NovaBay  Pharmaceuticals,  Inc.  In  August  2007,  it  formed  two  subsidiaries––NovaBay 
Pharmaceuticals Canada, Inc., a wholly-owned subsidiary incorporated under the laws of British Columbia (Canada), which 
was formed to conduct research and development in Canada and was dissolved in July 2012, and DermaBay, Inc., a wholly-
owned U.S. subsidiary, which may explore and pursue dermatological opportunities. In June 2010, it changed the state in 
which  it  is  incorporated  (the  “Reincorporation”),  and  is  now  incorporated  under  the  laws  of  the  State  of  Delaware.  All 
references to “the Company” herein refer to the California corporation prior to the date of the Reincorporation, and to the 
Delaware  corporation  on  and  after  the  date  of  the  Reincorporation.  Historically,  the  Company  operated  as  four  business 
segments.  At  the  direction  of  its  Board  of  Directors,  the  Company  is  focused  primarily  on  commercializing  prescription 
Avenova for managing hygiene of the eyelids and lashes in the United States and is now managed as a single business and 
not four segments. 

Effective December 11, 2015, we effected a 1-for-25 reverse split of our outstanding common stock (“Reverse Stock 

Split”) (See Note 9).  

Need to Raise Additional Capital 

We have incurred significant losses from operations since inception and expect losses to continue for the foreseeable 
future.  As  of  December  31,  2015,  we  had  cash  and  cash  equivalents  of  $2.4  million.  Our  operating  plans  call  for  cash 
expenditures to exceed $2.4 million over the next twelve months. We plan to raise additional capital to fund our operations. 
We  plan  to  finance  our  operations  through  the  sale  of  equity  securities,  debt  arrangements  or  partnership  or  licensing 
collaborations. Such funding may not be available or may be on terms that are not favorable to us. Our inability to raise 
capital as and when needed could have a negative impact on our financial condition and our ability to continue as a going 
concern.  If  we  become  unable  to  continue  as  a  going  concern,  we  may  have  to  liquidate  our  assets,  and  might  realize 
significantly less than the values at which they are carried on our financial statements, and stockholders may lose all or part 
of their investment in our common stock. 

The accompanying financial statements have been prepared assuming we will continue to operate as a going concern, 
which contemplates the realization of assets and the settlement of liabilities in the normal course of business. The consolidated 
financial  statements  do  not  include  any  adjustments  to  reflect  the  possible  future  effects  on  the  recoverability  and 
classification of assets or the amounts of liabilities that may result from uncertainty related to our ability to continue as a 
going concern. 

NOTE 2.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES 

Basis of Presentation 

The  accompanying  consolidated  financial  statements  have  been  prepared  in  accordance  with  accounting  principles 

generally accepted in the United States (“U.S. GAAP”) and are expressed in U.S. dollars.  

Reclassifications 

Prior  period  amounts  in  the  accompanying  consolidated  balance  sheets  have  been reclassified  to  conform  to  current 

period presentation. The reclassifications did not change total assets, total liabilities, or total stockholders’ equity.  

Principles of Consolidation 

The  accompanying  consolidated  financial  statements  include  the  accounts  of  the  Company  and  its  wholly-owned 

subsidiary, DermaBay, Inc. All inter-company accounts and transactions have been eliminated in consolidation. 

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Use of Estimates 

The preparation of financial statements in accordance with U.S. GAAP requires management to make estimates and 
assumptions  that  affect  the  amounts  reported  in  the  consolidated  financial  statements  and  accompanying  notes.  These 
estimates include useful lives for property and equipment and related depreciation calculations, estimated amortization period 
for payments received from product development and license agreements as they relate to revenue recognition, assumptions 
for valuing options and warrants, and income taxes. Actual results could differ from those estimates. 

Cash and Cash Equivalents and Short-Term Investments 

The Company considers all highly liquid instruments with a stated maturity of three months or less to be cash and cash 
equivalents. As of December 31, 2015, cash and cash equivalents were held in financial institutions in the U.S. and include 
deposits in money market funds, which were unrestricted as to withdrawal or use. 

The Company classifies all highly liquid investments with a stated maturity of greater than three months as short-term 
investments. Short-term investments generally consist of certificates of deposit and corporate debt securities. The Company 
has classified their short-term investments as available-for-sale. These securities are carried at fair value, with the unrealized 
gains and losses reported as a component of other comprehensive income (loss) until realized. Realized gains and losses from 
the sale of available-for-sale securities, if any, are determined on a specific identification basis. A decline in the market value 
below  cost  of  any  available-for-sale  security  that  is  determined  to  be  other  than  temporary  results  in  a  revaluation  of  its 
carrying amount to fair value and an impairment charge to earnings, resulting in a new cost basis for the security. No such 
impairment charges were recorded for the periods presented. The interest income and realized gains and losses are included 
in other income (expense), net, within the consolidated statements of operations. Interest income is recognized when earned. 

Concentrations of Credit Risk and Major Partners 

Financial instruments that potentially subject the Company to significant concentrations of credit risk consist primarily 
of cash and cash equivalents, short-term investments and accounts receivable. The Company maintains deposits of cash, cash 
equivalents and short-term investments with three highly-rated, major financial institutions in the United States. 

Deposits in these banks may exceed the amount of federal insurance provided on such deposits. The Company does not 
believe these deposits are exposed to significant credit risk due to the financial position of the financial institutions in which 
these  deposits  are  held.  Additionally,  the  Company  has  established  guidelines  regarding  diversification  and  investment 
maturities, which are designed to maintain safety and liquidity. 

During  the  year  ended  December  31,  2015,  revenues  were  derived  primarily  from  the  Company’s  webstore  selling 
Avenova  directly  to  doctors  and  through  sales  to  three  distribution  partners.  During  the  year  ended  December  31,  2014, 
revenues were derived from one collaboration partner and sales to two distribution partners, service revenues and sales of 
Avenova  and  NeutroPhase.  During  the  year  ended  December  31,  2013,  revenues  were  derived  from  two  collaboration 
partners, sales to two distribution partners, and sales of NeutroPhase products and service revenues. 

Fair Value of Financial Assets and Liabilities 

Financial instruments, including accounts receivable, accounts payable and accrued liabilities are carried at cost, which 

management believes approximates fair value due to the short-term nature of these instruments.  

The Company measures the fair value of financial assets and liabilities based on U.S. GAAP guidance, which defines 

fair value, establishes a framework for measuring fair value, and requires disclosures about fair value measurements. 

Under U.S. GAAP, fair value is defined as the exchange price that would be received for an asset or paid to transfer a 
liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between 
market participants on the measurement date. A fair value hierarchy is also established, which requires an entity to maximize 
the use of observable inputs and minimize the use of unobservable inputs when measuring fair value. There are three levels 
of inputs that may be used to measure fair value: 

Level 1 – quoted prices in active markets for identical assets or liabilities; 
Level 2 – quoted prices for similar assets and liabilities in active markets or inputs that are observable; 
Level 3 – inputs that are unobservable (for example cash flow modeling inputs based on assumptions). 

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Allowance for Doubtful Accounts 

We charge Bad Debt expense and record an Allowance for Doubtful Accounts when management believes is unlikely 
specific invoices will be collected. Management identified amounts due that are in dispute and it believes are unlikely to be 
collected at the end of 2015. At December 31, 2015, management had reserved $40 thousand, primarily based on specific 
amounts that are in dispute and are over 120 days past due. 

Inventory 

Inventory is: (1) raw materials and supplies, such as bottles, packaging materials, labels, boxes, pumps; (2) goods in 
progress,  which  are  normally  unlabeled  bottles;  and  (3)  finished  goods.  The  Company  utilizes  contract  manufacturers  to 
produce its products and the cost associated with maufacturing is included in inventory. 

Inventory is stated at the lower of cost or market value determined by the first-in, first-out method. 

Property and Equipment 

Property and equipment are stated at cost, less accumulated depreciation and amortization. Depreciation is calculated 
using the straight-line method over the estimated useful lives of the related assets, which are five to seven years for office 
and laboratory equipment, three years for software and seven years for furniture and fixtures. Leasehold improvements are 
depreciated over the shorter of seven years or the lease term.  

The costs of normal maintenance, repairs, and minor replacements are charged to operations when incurred. 

Impairment of Long-Lived Assets 

The Company accounts for long-lived assets in accordance with U.S. GAAP, which requires that companies consider 
whether events or changes in facts and circumstances, both internally and externally, may indicate that impairment of long-
lived  assets  held  for  use  is  present.  Management  periodically  evaluates  the  carrying  value  of  long-lived  assets  and  has 
determined that there was no impairment as of all periods presented. Determination of recoverability is based on the estimate 
of undiscounted future cash flows resulting from the use of the asset and its eventual disposition. In the event that such cash 
flows  are  not  expected  to  be  sufficient  to  recover  the  carrying  amount  of  the  asset,  the  assets  are  written  down  to  their 
estimated fair values and the loss is recognized in the statements of operations. 

Comprehensive Income (Loss) 

ASC  220,  Comprehensive  Income,  requires  that  an  entity’s  change  in  equity  or  net  assets  during  a  period  from 
transactions and other events from non-owner sources be reported. The Company reports unrealized gains and losses on its 
available-for-sale securities as other comprehensive income (loss). 

Revenue Recognition 

The  Company  sells  products  through  a  limited  number  of  distributors  and  via  its  webstore.  The  Company  generally 
records product sales upon shipment to the final customer for its webstore sales and upon shipment from its distributor to the 
final customers for its major distribution partners. 

We recognize product revenue when: (i) persuasive evidence that an arrangement exists, (ii) delivery has occurred and 
title  has  passed, (iii)  the  price  is  fixed  or determinable,  and  (iv) collectability  is  reasonably  assured.  Revenue  from  sales 
transactions where the customer has the right to return the product is recognized at the time of sale only if: (i) our price to the 
customer is substantially fixed or determinable at the date of sale, (ii) the customer has paid us, or the customer is obligated 
to pay us and the obligation is not contingent on resale of the product, (iii) the customer's obligation to us would not be 
changed in the event of theft or physical destruction or damage of the product, (iv) the customer acquiring the product for 
resale  has  economic  substance  apart  from  that  provided  by  us,  (v)  we  do  not  have  significant  obligations  for  future 
performance  to  directly  bring  about  resale  of  the  product  by  the  customer,  and  (vi)  the  amount  of  future  returns  can  be 
reasonably estimated.  

Product Revenue Allowances  

Product revenue is recognized net of cash consideration paid to our customers and wholesalers, for services rendered by 
the wholesalers accordance with the wholesalers agreements, and include a fixed rate per prescription shipped and monthly 

39 

 
  
  
  
  
  
  
  
  
  
  
  
   
   
  
  
  
program management and data fees. These services are not deemed sufficiently separable from the customers' purchase of 
the product; therefore, they are recorded as a reduction of revenue at the time of revenue recognition.  

Other  product  revenue  allowances  include  certain  prompt  pay  discounts  and  allowances  offered  to  our  customers, 
program rebates and chargebacks. These product revenue allowances are recognized as a reduction of revenue or as a selling 
expense at the later of the date at which the related revenue is recognized or the date at which the allowance is offered. 

Other Revenue 

License and collaboration revenue is primarily generated through agreements with strategic partners for the development 
and commercialization of our product candidates. The terms of the agreements typically include non-refundable upfront fees, 
funding of research and development activities, payments based upon achievement of certain milestones and royalties on net 
product sales. In accordance with authoritative guidance, we analyze our multiple element arrangements to determine whether 
the elements can be separated. We perform our analysis at the inception of the arrangement and as each product or service is 
delivered. If a product or service is not separable, the combined deliverables are accounted for as a single unit of accounting 
and revenue is recognized over the performance obligation period. Revenue is recognized when the following criteria have 
been met: persuasive evidence of an arrangement exists; delivery has occurred and risk of loss has passed; the seller’s price 
to  the buyer  is  fixed  or determinable;  and  collectability  is  reasonably  assured. If  these  factors  were  to  vary  the resulting 
change could have a material effect on our revenue recognition and on our results of operations. 

Cost of Goods Sold 

Cost of goods sold includes third party manufacturing costs, shipping costs, and other costs of goods sold. Cost of goods 
sold  also  includes  any  necessary  allowances  for  excess  inventory  that  may  expire  and  become  unsalable.  The  Company 
recorded  an  allowance  for  obsolete  inventory  of  $45  thousand  during  2015,  but  did  not  record  an  allowance  for  excess 
inventory as of December 31, 2015.  

Research and Development Costs 

The Company charges research and development costs to expense as incurred. These costs include salaries and benefits 
for research and development personnel, costs associated with clinical trials managed by contract research organizations, and 
other  costs  associated  with  research,  development  and  regulatory  activities.  Research  and  development  costs  may  vary 
depending on the type of item or service incurred, location of performance or production, or lack of availability of the item 
or service, and specificity required in production for certain compounds. The Company uses external service providers to 
conduct clinical trials, to manufacture supplies of product candidates and to provide various other research and development-
related  products  and  services.  The  Company’s  research,  clinical  and  development  activities  are  often  performed  under 
agreements it enters into with external service providers.  The Company estimates and accrues the costs incurred under these 
agreements based on factors such as milestones achieved, patient enrollment, estimates of work performed, and historical 
data for similar arrangements.  As actual costs are incurred, the Company adjusts its accruals.  Historically, the Company’s 
accruals  have  been  consistent  with  management’s  estimates,  and  no  material  adjustments  to  research  and  development 
expenses have been recognized.  Subsequent changes in estimates may result in a material change in the Company’s expenses, 
which could also materially affect its results of operations. 

Patent Costs 

Patent costs, including legal expenses, are expensed in the period in which they are incurred. Patent expenses are included 

in sales, general and administrative expenses in the consolidated statements of operations. 

Stock-Based Compensation 

The  Company  accounts  for  stock-based  compensation  under  the  provisions  of  ASC  718,  Compensation-Stock 
Compensation. Under the fair value recognition provisions, stock-based compensation expense is measured at the grant date 
for all stock-based awards to employees and directors and is recognized as expense over the requisite service period, which 
is generally the vesting period. Forfeitures are estimated at the time of grant and reduce compensation expense ratably over 
the vesting period. This estimate is adjusted periodically based on the extent to which actual forfeitures differ, or are expected 
to differ, from the previous estimate. See Note 10 of the Notes to Consolidated Financial Statements for further information 
regarding stock-based compensation expense and the assumptions used in estimating that expense. For stock options granted 
to employees, the fair value of the stock options is estimated using a Black-Scholes-Merton option pricing model.  

40 

 
  
  
  
   
  
  
  
  
  
  
  
  
Stock-based compensation arrangements with non-employees are recorded at their fair value on the measurement date. 
The measurement of stock-based compensation is subject to periodic adjustment as the underlying equity instruments vest. 
Non-employee stock-based compensation charges are amortized over the vesting period on a straight-line basis. For stock 
options  granted  to  non-employees,  the  fair  value  of  the  stock  options  is  estimated  using  a  Black-Scholes-Merton  option 
pricing model. 

Income Taxes 

The  Company  accounts  for  income  taxes under  the  asset and  liability  method.  Deferred  tax  assets  and  liabilities  are 
recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of 
existing assets and liabilities and their respective tax bases and operating loss and tax credit  carryforwards. Deferred tax 
assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those 
temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in 
tax rates is recognized in income in the period that includes the enactment date. A valuation allowance is recognized if it is 
more likely than not that some portion or the entire deferred tax asset will not be recognized. 

Common Stock Warrant Liabilities 

For warrants that are newly issued or modified and there is a deemed possibility that we may have to settle them in 
cash, or for warrants we issue or modify that contain an exercise price adjustment feature that reduces the exercise price and 
increases the number of shares of our common stock eligible for purchase thereunder in the event we subsequently issue 
equity instruments at a price lower than the exercise price of the warrants, we record the fair value of the issued or modified 
warrants as a liability at each balance sheet date and record changes in the estimated fair value as a non-cash gain or loss on 
the consolidated statements of operations and comprehensive loss. The fair values of these warrants have been determined 
using the Binomial Lattice (“Lattice”) valuation model, and the change in the fair value are recorded in the consolidated 
statements of operations and comprehensive gain or loss. The Lattice model provides for assumptions regarding volatility, 
call and put features and risk-free interest rates within the total period to maturity. These values are subject to a significant 
degree of our judgment.   

Net Income (Loss) per Share 

The  Company  computes  net  income  (loss)  per  share  by  presenting  both  basic  and  diluted  earnings  (loss)  per  share 

(“EPS”). 

Basic EPS is computed by dividing net income (loss) available to common shareholders by the weighted average number 
of common shares outstanding during the period. Diluted EPS gives effect to all dilutive potential common shares outstanding 
during  the period,  including  stock  options  and warrants, using  the  treasury  stock  method. In  computing diluted  EPS,  the 
average stock price for the period is used to determine the number of shares assumed to be purchased from the exercise of 
stock options or warrants. Potentially dilutive common share equivalents are excluded from the diluted EPS computation in 
net loss periods because their effect would be anti-dilutive. During years ended December 31, 2015, 2014 and 2013, there is 
no difference between basic and diluted net loss per share due to the Company’s net losses. The following table sets forth the 
reconciliation between basic EPS and diluted EPS, after giving effect to the reverse stock split. 

Year Ended December 31,  

(in thousands, except per share data) 

2015 

2014 

2013 

Net loss .........................................................................................    $ 

(18,973)   $ 

(15,179)   $ 

(16,044 ) 

Basic shares ..................................................................................      
Add: shares issued upon assumed exercise of stock options and 

warrants .....................................................................................      
Diluted shares ...............................................................................      

Basic EPS .....................................................................................    $ 
Diluted EPS ..................................................................................    $ 

2,784      

1,985       

—      
2,784      

(6.82)   $ 
(6.82)   $ 

—      
1,985       

(7.65)   $ 
(7.65)   $ 

1,527   

—   
1,527   

(10.51 ) 
(10.51 ) 

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The following outstanding stock options and stock warrants were excluded from the diluted EPS computation as their 

effect would have been anti-dilutive:  

(in thousands) 
Stock options ..........................................................................     
Stock warrants ........................................................................     

2015 

Year Ended December 31,  
2014 

2013 

388      
1,458      

323      
197      

287  
192  

Recent Accounting Pronouncements 

In April 2015, the FASB issued Accounting Standards Update 2015-3, Simplifying the Presentation of Debt Issuance 
Costs , which requires debt issuance costs to be presented in the balance sheet as a direct deduction from the carrying value 
of the associated debt liability, consistent with the presentation of a debt discount. The recognition and measurement guidance 
for debt issuance costs are not affected by this guidance. The guidance is effective for financial statements issued for fiscal 
years beginning after December 15, 2015, and interim periods within those fiscal years. The Company is currently evaluating 
the method of adoption and the impact of adopting ASU 2015-3 on its results of operations, cash flows and financial position. 

In May 2014, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update No. 2014-09, 
Revenue from Contracts with Customers. The updated standard will replace most existing recognition guidance in U.S. GAAP 
when it becomes effective and permits the use of either the retrospective or cumulative effect transition method. In August 
2015,  the  FASB  issued  an  update  to  defer  the  effective  date  of  this  update  by  one  year.  The  updated  standard  becomes 
effective for the Company in the first quarter of 2018, but allows the Company to adopt the standard one year earlier if it is 
so choses. The Company has not yet elected a transition method and is currently evaluating the effect that the updated standard 
will have on its results of operations, cash flows and financial position. 

In July 2015, the FASB issued ASU 2015-11, Inventory (Topic 330) Related to Simplifying the Measurement of Inventory 
which applies to all inventory measured using first-in, first-out (“FIFO”) or average cost. Inventory within the scope of the 
new guidance should be measured at the lower of cost and net realizable value. Net realizable value is the estimated selling 
prices in the ordinary course of business, less reasonably predictable costs of completion, disposal, and transportation. The 
amendments will be effective for the Company beginning in fiscal 2017, including interim periods within fiscal 2017. The 
new guidance should be applied prospectively, and earlier application is permitted as of the beginning of an interim or annual 
reporting period. The Company is currently evaluating the method of adoption and the impact of adopting ASU 2015-11 on 
its results of operations, cash flows and financial position. 

In February 2016, the FASB issued ASU 2016-02, Leases (Topic 842) which supersedes FASB ASC Topic 840, Leases 
(Topic 840) and provides principles for the recognition, measurement, presentation and disclosure of leases for both lessees 
and lessors. The new standard requires lessees to apply a dual approach, classifying leases as either finance or operating 
leases based on the principle of whether or not the lease is effectively a financed purchase by the lessee. This classification 
will determine whether lease expense is recognized based on an effective interest method or on a straight-line basis over the 
term of the lease, respectively. A lessee is also required to record a right-of-use asset and a lease liability for all leases with 
a  term  of  greater  than  twelve  months  regardless  of  classification.  Leases  with  a  term  of  twelve  months  or  less  will  be 
accounted  for  similar  to  existing  guidance  for  operating  leases.  The  standard  is  effective  for  annual  and  interim  periods 
beginning after December 15, 2018, with early adoption permitted upon issuance. The Company is currently evaluating the 
method of adoption and the impact of adopting ASU 2016-02 on its results of operations, cash flows and financial position. 

NOTE 3. FAIR VALUE MEASUREMENTS  

The Company measures the fair value of financial assets and liabilities based on authoritative guidance that defines fair 
value, establishes a framework consisting of three levels for measuring fair value, and requires disclosures about fair value 
measurements. Fair value is defined as the exchange price that would be receive for an asset or paid to transfer a liability (an 
exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market 
participants on the measurement date.  

The Company’s cash equivalents and investments are classified within Level 1 or Level 2 of the fair value hierarchy 
because  they  are  valued using  quoted  market  prices  in  active  markets,  broker or dealer  quotations,  or  alternative  pricing 
sources with reasonable levels of price transparency. The types of investments that are generally classified within Level 1 of 
the fair value hierarchy include money market securities. The types of investments that are generally classified within Level 
2 of the fair value hierarchy include corporate securities, certificates of deposits and U.S. government securities. 

42 

 
  
  
  
  
  
    
    
  
  
   
  
  
     
  
  
  
  
The Company’s warrant liability is classified within level 3 of the fair value hierarchy because the value is calculated 

using significant judgment based on our own assumptions in the valuation of this liability. 

The  following  table  presents  the  Company’s  assets  and  liabilities  measured  at  fair  value  on  a  recurring  basis  as  of 

December 31, 2015: 

Fair Value Measurements Using 

Quoted 
Prices in  
Active 
Markets  
for Identical 
Items  
(Level 1) 

Significant  
Other  
Observable  
Inputs  
(Level 2) 

Significant  
Unobservable 
Inputs  
(Level 3) 

Balance at  
December 
31, 2015 

2,385     $ 
2,385    $ 

2,385    $ 
2,385    $ 

—    $ 
—    $ 

—  
—  

(in thousands) 
Assets 
Cash equivalents ...................................................................   $ 
Total assets ...........................................................................   $ 

Liabilities 
Warrant liability ...................................................................   $ 
Total liabilities .....................................................................   $ 

1,450    $ 
1,450     $ 

—    $ 
—    $ 

—    $ 
—    $ 

1,450   
1,450   

For the year ended December 31, 2014, as a result of the fair value adjustment of the warrant liability, the Company 
recorded  a  non-cash  gain  on  a  change  in  the  fair  value  of  $1.7  million  in  its  consolidated  statements  of  operations  and 
comprehensive loss.  See Note 8 for further discussion on the calculation of the fair value of the warrant liability. 

(in thousands) 
Fair value of warrants at December 31, 2012 ........................................................................................   $ 
Increase in fair value at December 31, 2013 ......................................................................................     
Total warrant liability at December 31, 2013 ........................................................................................     
Decrease in fair value at December 31, 2014 ....................................................................................     
Total warrant liability at December 31, 2014 ........................................................................................     
Warrants issued..................................................................................................................................     
Increase in fair value at December 31, 2015 ......................................................................................     
Total warrant liability at December 31, 2015 .........................................................................   $ 

   Warrant liability    
1,282   
555   
1,837   
(1,664) 
173   
3,426   
(2,149) 
1,450   

NOTE 4. INVENTORY  

Inventory consisted of the following: 

(in thousands) 
Raw materials and supplies ..............................................................................   $ 
Goods in process ..............................................................................................     
Finished goods .................................................................................................     
Less Reserve for obsolete inventory ................................................................     
Total inventory, net ..........................................................................................   $ 

December 31, 
2015 

December 31,  
2014 

660    $ 
248      
482      
(45)     
1,345    $ 

260  
184  
77   
—  
521  

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NOTE 5. PROPERTY AND EQUIPMENT  

Property and equipment consisted of the following: 

(in thousands) 
Office and laboratory equipment ..............................................................................   $ 
Furniture and fixtures ...............................................................................................     
Software ...................................................................................................................     
Leasehold improvements ..........................................................................................     
Total property and equipment, at cost ......................................................................     
Less: accumulated depreciation................................................................................     
Total property and equipment, net ...........................................................................   $ 

December 31, 
2015 

December 31,  
2014 

1,633     $ 
254       
37       
173      
2,097       
(1,702)     
395     $ 

1,697  
98   
9   
172   
1,976   
(1,540) 
436   

Depreciation  and  amortization  expense  was  $164  thousand,  $232  thousand  and  $314  thousand  for  the  years  ended 

December 31, 2015, 2014 and 2013, respectively. 

NOTE 6. ACCRUED LIABILITIES  

Accrued liabilities consisted of the following: 

(in thousands) 
Research and development .......................................................................................   $ 
Employee payroll and benefits .................................................................................     
Severance pay...........................................................................................................     
Sales rebate ..............................................................................................................     
Other.........................................................................................................................     
Total accrued liabilities ............................................................................................   $ 

December 31,  
2015 

December 31,  
2014 

394    $ 
614       
590       
150      
232       
1,980    $ 

209   
667  
—  
—  
179  
1,055  

NOTE 7. RELATED PARTY NOTES PAYABLE 

Beginning on December 30, 2015, NovaBay Pharmaceuticals, Inc. (the “Company”) entered into a series of agreements 
pursuant to a loan (the “Loan”) facilitated by China Kington Asset Management Co. Ltd. (“China Kington”). In connection 
with  the  Loan,  the  Company  issued  or  will  soon  issue  five  (5)  promissory  notes  (the  “Notes”)  payable  to  Mr.  Mark 
Sieczkarek, the Gail J. Maderis Revocable Trust, Dr. T. Alex McPherson, Mr. Jian Ping Fu, and Pioneer Pharma (Singapore) 
Pte.  Ltd.  (“Pioneer”)  (collectively,  the  “Lenders”),  loaning  the  Company  an  aggregate  of  $3,020,000.  Specifically,  Mr. 
Sieczkarek, Chairman of the Board of the Company (the “Board”) and Interim President and Chief Executive Officer of the 
Company, loaned the Company $199,000; the Gail J. Maderis Revocable Trust, on behalf of Ms. Maderis, a Director of the 
Company,  loaned  the  Company  $71,000;  Dr.  McPherson,  a  Director  of  the  Company,  loaned  the  Company 
$20,000; Pioneer loaned the Company $1,365,000; and Mr. Fu has promised to loan the Company $1,365,000. All Notes 
were issued on December 30, 2015 except the Note payable to Mr. Fu, which will be issued in January 2016 upon receipt of 
such funds. 

The proceeds from the Notes are to be used for general corporate purposes. Minimum quarterly payments of principal 
and  interest  will  begin  on  March  31,  2016  and  continue  on  the  last  day  of  each  June,  September,  December  and  March 
thereafter. The entire principal sum and any and all accrued and unpaid interest is payable in full upon the Company’s next 
financing, but in no event shall the term of the Loan extend beyond December 30, 2018, except for the loan by Mr. Fu, the 
term of which shall extend three (3) years from the date of issuance of the Note payable to Mr. Fu. The Notes will pay interest 
at a rate of six percent (6%) per annum and may be prepaid in whole or in part at any time without premium or penalty.  

In  connection  with  the  Notes,  China  Kington  has  agreed  to  act  as  collateral  agent  for  the  benefit  of  the  Lenders,  in 
accordance with the terms of a collateral agency and intercreditor agreement (the “Collateral Agency Agreement”), which 
was entered into on December 30, 2015 between China Kington and the Lenders. To secure the Notes, China Kington shall 
have a perfected security interest in all tangible and intangible assets of the Company, pursuant to a security agreement (the 
“Security Agreement”) between the Company and China Kington, which was entered into on December 30, 2015. 

As consideration to China Kington for facilitating the Loan, the Company agreed to the following: (1) the grant of a first 
right of refusal for China Kington (or its designee that shall be acceptable to the Company in its reasonable discretion) to 
lead financings for the Company for a period that is the shorter of two (2) years or the day that the Company’s cash flow has 
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been  equal  to  or  greater  than  $0  in  each  month  for  three  (3)  consecutive  months,  subject  to  certain  limitations;  (2)  the 
participation of Mr. Sieczkarek as a Lender in this financing; (3) the participation of the Company’s Board, management and 
investors that the Board and management provide, to contribute an aggregate nine percent (9%) of funds in the Company’s 
next financing; (4) the appointment of two new members to the Company’s Board to be named in the future by China Kington; 
and (5) the Company’s agreement to reasonably cooperate with reasonable requests made by an auditor engaged, and paid 
for, by China Kington, subject to certain limitations.  

As of December 31, 2015, outstanding amounts under these notes was $1.7 million. 

See the Neutrophase Distribution Agreements section of Note 12 for description of the Company’s relationship with 

Pioneer Pharma Co., Ltd. 

NOTE 8. COMMITMENTS AND CONTINGENCIES  

Operating Leases 

We lease laboratory facilities and office space under an operating lease, which expires on October 31, 2020. Rent expense 
was  $1,008  thousand,  $1,045  thousand,  and  $966  thousand  for  the  years  ended  December  31,  2015,  2014  and  2013, 
respectively.  The  future  minimum  lease  payments  under  this  non-cancellable  operating  lease  were  as  follows  as  of 
December 31, 2015: 

(in thousands) 
Year ending December 31: 

  Lease Commitment   

2016 ...................................................................................................................................................   $ 
2017 ...................................................................................................................................................     
2018 ...................................................................................................................................................     
2019 ...................................................................................................................................................     
2020 ...................................................................................................................................................     
Total lease commitment ........................................................................................................................   $ 

643   
662   
682   
703   
600   
3,290   

The Company’s monthly rent payments fluctuate under the master lease agreement. In accordance with U.S. GAAP, the 
Company recognizes rent expense on a straight-line basis, and records deferred rent for the difference between the amounts 
paid and recorded as expense. At December 31, 2015 and 2014, the Company had $189 thousand and $171 thousand of 
deferred rent, respectively.  

Directors and Officers Indemnity 

As permitted under Delaware law and in accordance with our bylaws, we indemnify our officers and directors for certain 
events  or  occurrences  while  the  officer  or  director  is  or  was  serving  at  our  request  in  such  capacity.  The  term  of  the 
indemnification period is for the officer’s or director’s lifetime. The maximum amount of potential future indemnification is 
unlimited; however, we have a director or officer insurance policy that limits our exposure and may enable us to recover a 
portion of any future payments. We believe the fair value of these indemnification agreements is minimal. Accordingly, we 
have not recorded any liabilities for these agreements as of December 31, 2015. 

In  the  normal  course  of  business,  we  provide  indemnifications  of  varying  scope  under  our  agreements  with  other 
companies, typically our clinical research organizations, investigators, clinical sites, suppliers and others. Pursuant to these 
agreements, we generally indemnify, hold harmless, and agree to reimburse the indemnified parties for losses suffered or 
incurred by the indemnified parties in connection with use or testing of our products or product candidates or with any U.S. 
patent or any copyright or other intellectual property infringement claims by any third party with respect to our products. The 
term of these indemnification agreements is generally perpetual. The potential future payments we could be required to make 
under these indemnification agreements is unlimited. Historically, costs related to these indemnification provisions have been 
immaterial. We also maintain various liability insurance policies that limit our exposure. As a result, we believe the fair value 
of these indemnification agreements is minimal. Accordingly, we have not recorded any liabilities for these agreements as of 
December 31, 2015.  

Legal Matters 

From time to time, the Company may be involved in various legal proceedings arising in the ordinary course of business. 
There are no matters at December 31, 2015, that, in the opinion of management, would have a material adverse effect on our 
financial position, results of operations or cash flows. 

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NOTE 9. WARRANT LIABILITY  

In  July  2011,  the  Company  sold  common  stock  and  warrants  in  a  registered  direct  financing.  As  part  of  this 
transaction, 139,520 warrants were issued with an exercise price of $33.25 and were exercisable from January 1, 2012 to July 
5, 2016. The terms of the warrants require registered shares to be delivered upon each warrant’s exercise and also require 
possible cash payments to the warrant holders (in lieu of the warrant’s exercise) upon specified fundamental transactions 
involving  the  Company’s  common  stock,  such  as  in  an  acquisition  of  the  Company.  Under  ASC  480,  Distinguishing 
Liabilities  from  Equity,  the  Company’s  ability  to  deliver  registered  shares  upon  an  exercise  of  the  warrants  and  the 
Company’s  potential  obligation  to  cash-settle  the  warrants  if  specified  fundamental  transactions  occur  are  deemed  to  be 
beyond  the  Company’s  control.  The warrants  contain  a provision  according  to which  the warrant holder would have  the 
option to receive cash, equal to the Black Scholes fair value of the remaining unexercised portion of the warrant, as cash 
settlement in the event that there is a fundamental transaction (contractually defined to include various merger, acquisition 
or stock transfer activities). Due to this provision, ASC 480 requires that these warrants be classified as liabilities. The fair 
values of these warrants have been determined using the Binomial Lattice (“Lattice”) valuation model, and the changes in 
the fair value are recorded in the consolidated statement of operations. The Lattice model provides for assumptions regarding 
volatility and risk-free interest rates within the total period to maturity. In addition, after January 5, 2012, and if the closing 
bid price per share of the common stock in the principal market equals or exceeds $66.50 for any ten trading days (which do 
not have to be consecutive) in a period of fifteen consecutive trading days, the Company has the right to require the exercise 
of one-third of the warrants then held by the warrant holders.  

In  October  2015,  the  holders  of  all  warrants  issued  pursuant  to  the  Company’s  securities  purchase  agreement  dated 
March 3, 2015 (the “Agreement”) agreed to reduce the length of notice required to such investors prior to the Company’s 
issuance of new securities from twenty business days to two business days, for the remainder of such investors’ pre-emptive 
right period (expiring March 3, 2016). The Company entered into these agreements to enable it to expeditiously raise capital 
in the Offering (as described below) and future offerings. As consideration for these agreements, the Company amended 
certain provisions of both the Short-Term Warrants and Long-Term Warrants issued pursuant to the Agreement (together, 
the “March 2015 Warrants”) and the warrants issued pursuant to the placement agent agreement dated June 29, 2011 (the 
“2011 Warrants”). Specifically, the amendments decreased the exercise price for both the March 2015 Warrants and the 2011 
Warrants to $5.00 per share. In addition, the amendments extended the exercise expiration date for the Short-Term Warrants 
and the 2011 Warrants to March 6, 2020. A price protection provision also was added to both the 2011 Warrants and March 
2015 Warrants, such that if the Company subsequently sells or otherwise disposes of Company common stock at a lower 
price  per  share  than  $5.00  or  any  securities  exchangeable  for  common  stock  with  a  lower  exercise  price  than  $5.00,  the 
exercise price of such warrants will be reduced to that lower price. 

In October 2015, the Company also entered into an underwriting agreement with Roth Capital Partners, LLC, relating to 
the public offering and sale of up to (i) 492,000 shares of the Company’s common stock; and (ii) warrants to purchase up 
to 442,802 shares of the Company’s common stock with an exercise price of $5.00 per share.  

The  shares  of  common  stock  and  warrants  were  issued  separately.  Each  warrant  was  exercisable  immediately  upon 
issuance and will expire 60 months from the date of issuance. The price to the public in this offering was $5.00 per share of 
common  stock  and  related  warrant.  The  net  proceeds  to  the  Company  were  approximately  $2.1  million  after  deducting 
underwriting discounts and commissions and offering expenses.  

The Company evaluated the change in terms of the July 2011 warrants and noted that the change in terms resulted in a 
revaluation at the time of the change. The warrants were re-issued and valued as of October 27, 2015 at $360,821 with the 
new terms, and a modification expense was recorded for the difference between the fair value of the warrants at their new 
terms after modification on October 27, 2015 and the fair value of the warrants at their original terms prior to modification 
as  of  October  27,  2015.  The  fair  values  of  these  warrants  have  been  determined  using  the  Binomial  Lattice  (“Lattice”) 
valuation model, and the changes in the fair value are recorded in the consolidated statement of operations. 

The key assumptions used to value the warrants after the modification at October 27, 2015 were as follows: 

Assumption 
Expected price volatility .......................................................................................................................     
Expected term (in years) ......................................................................................................................     
Risk-free interest rate ...........................................................................................................................     
Dividend yield ......................................................................................................................................     
Weighted-average fair value of warrants .............................................................................................   $ 

80.00% 
4.36  
1.23% 
0.00% 
2.60  

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The key assumptions used to value the warrant after the modification at December 31, 2015 were as follows: 

Assumption 
Expected price volatility ..........................................................................................      
Expected term (in years) .........................................................................................      
Risk-free interest rate ..............................................................................................      
Dividend yield .........................................................................................................      
Weighted-average fair value of warrants ................................................................    $ 

Year Ended December 31,  
2015 

2014 

80.00 %     
4.18        
1.58 %     
0.00 %     
1.10      $ 

60% 

1.51  
0.47% 
0.00% 
1.25  

In  March 2015,  the  Company  issued both short-term  (15-month  term;  $0.60  per  share  exercise price)  and  long-term 
warrants (60-month term; $0.65 per share exercise price). At that time the Company determined that these warrants qualified 
for equity accounting and did not contain embedded derivatives that required bifurcation. After the October 2015 Agreement 
noted above, the Company evaluated the change in terms of the March 2015 warrants and noted that the change in terms 
resulted in liability classification of both the long-term (“Long-term”) and short-term (“Short-term”) warrants. The warrants 
were re-issued and valued as of October 27, 2015 at a total of $1,821,508 with the new terms and a modification expense was 
recorded at the difference between the fair value of the warrants on their new terms after modification as of October 27, 2015 
and the fair value of the warrants on their original terms prior to modification as of October 27, 2015. The fair values of these 
warrants have been determined using the Binomial Lattice (“Lattice”) valuation model, and the changes in the fair value are 
recorded in the consolidated statement of operations. 

The key assumptions used to value the warrants after the modification at October 27, 2015 were as follows: 

Assumption 
Expected price volatility .......................................................................................................................   
Expected term (in years) ......................................................................................................................   
Risk-free interest rate ...........................................................................................................................   
Dividend yield ......................................................................................................................................   
Weighted-average fair value of warrants ............................................................................................. 

The key assumptions used to re-value the warrants at December 31, 2015 were as follows: 

Assumption 
Expected price volatility .......................................................................................................................   
Expected term (in years) ......................................................................................................................   
Risk-free interest rate ...........................................................................................................................   
Dividend yield ......................................................................................................................................   
Weighted-average fair value of warrants ............................................................................................. 

$

$

80.00% 
4.36  
1.23% 
0.00% 
2.78  

80.00% 
4.18  
1.58% 
0.00% 
1.16  

As noted above, in October 2015, the Company issued warrants in connection with an underwriting agreement. The 
Company evaluated the terms of the warrants and noted that under ASC 480, the Company’s potential obligation to cash-
settle the warrants if specified fundamental transactions occur are deemed to be beyond the Company’s control. Due to this 
provision,  ASC  480  requires  that  these  warrants  be  classified  as  liabilities.  The  fair  values  of  these  warrants  have  been 
determined using the Binomial Lattice (“Lattice”) valuation model, and the changes in the fair value are recorded in the 
consolidated statement of operations. The fair value of the warrants at issuance was $1,250,453. 

The key assumptions used to initially value the warrants at October 27, 2015 were as follows: 

Assumption 
Expected price volatility .......................................................................................................................     
Expected term (in years) ......................................................................................................................     
Risk-free interest rate ...........................................................................................................................     
Dividend yield ......................................................................................................................................     
Weighted-average fair value of warrants .............................................................................................   

$

75.50% 
5.00  
1.38% 
0.00% 
2.82  

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The key assumptions used to re-value the warrants at December 31, 2015 were as follows: 

Assumption 
Expected price volatility .......................................................................................................................     
Expected term (in years) ......................................................................................................................     
Risk-free interest rate ...........................................................................................................................     
Dividend yield ......................................................................................................................................     
Weighted-average fair value of warrants .............................................................................................   

$

77.50% 
4.83  
1.72% 
0.00% 
1.21  

NOTE 10. STOCKHOLDERS’ EQUITY  

Amendments to Articles of Incorporation – Reverse Stock Split 

Effective December 11, 2015, we amended our Certificate of Incorporation to effect a 1 - for - 25 reverse split of our 
outstanding  common  stock.  The  Reverse  Stock  Split  was  approved  by  our  stockholders  on  December  11,  2015.  The 
accompanying financial statements and related notes give retroactive effect to this reverse stock split. 

Preferred Stock 

Under the Company’s amended articles of incorporation, the Company is authorized to issue of up to 5,000,000 shares 
of preferred stock in such series and with such rights and preferences as may be approved by the board of directors. As of 
December 31, 2015, there were no shares of preferred stock outstanding. 

Common Stock 

On November 14, 2013, the Company entered into an At-The-Market Offering Agreement (“2013 ATM Agreement”), 
with  Ascendiant  Capital  Markets  (“Ascendiant”)  as  its  agent,  and  filed  a  prospectus  supplement  to  its  shelf  registration 
statement, pursuant to which the Company may offer and sell shares of its common stock having an aggregate offering price 
of up to $5.0 million from time to time.  

On October 16, 2014, the Company entered into an At-The-Market Offering Agreement (the “2014 ATM Agreement”, 
the “Agreement”) with Ascendiant under which it may offer and sell its common stock having aggregate sales proceeds of 
up  to  $10.0  million  from  time  to  time  through  Ascendiant  as  its  sales  agent.  Sales  of  Company  common  stock  through 
Ascendiant are made by means of ordinary brokers’ transactions on the NYSE MKT or otherwise at market prices prevailing 
at the time of sale, in block transactions, or as otherwise agreed upon by the Company and Ascendiant. Ascendiant uses 
commercially reasonable efforts to sell Company common stock from time to time, based upon instructions from it (including 
any price, time or size limits or other customary parameters or conditions it may impose). The Company pays Ascendiant a 
commission of 3.0% of the gross sales proceeds of any common stock sold through Ascendiant under the Agreement. The 
Company  has  also  provided  Ascendiant  with  customary  indemnification  rights.  In  connection  with  the  Agreement,  the 
Company terminated the At-The-Market Offering Agreement with Ascendiant dated November 13, 2013. 

The Company is not obligated to make any sales of common stock under the Agreement. The offering of shares of the 
Company’s common stock pursuant to the Agreement will terminate upon the earlier of (i) the sale of all common stock 
subject to the Agreement, or (ii) termination of the Agreement in accordance with its terms. 

For  the  year  ended December  31,  2014,  the  Company  sold 1.3  million  shares  for  gross  proceeds of $1.2  million, or 
approximately $1.1 million in net proceeds after deducting offering costs and commissions of $81 thousand. For the year 
ended December 31, 2013, the Company sold 289,492 shares for gross proceeds of $378 thousand, or approximately $352 
thousand in net proceeds after deducting offering costs and commissions of $26 thousand. Under the terms of the 2014 and 
2013 ATM Agreement, the Company paid Ascendiant 3% of the gross proceeds of all sales made under these agreements.  

On March 25, 2014, the Company closed a public offering for the sale of 224,000 units, each unit consisting of (i) one 
share of common stock and (ii) one warrant to purchase 6.25 of a share of common stock (or a total of 56,000 shares), at a 
purchase price of $30.00 per unit. The warrants were immediately exercisable for $39.00 per share and will expire eighteen 
months from the date of issuance. All of the shares of common stock and warrants issued in the offering (and the shares of 
common stock issuable upon exercise of the warrants) were offered pursuant to a shelf registration statement filed with, and 
declared  effective  by,  the  Securities  and  Exchange  Commission.  The  shares  of  common  stock  and  the  warrants  were 
immediately separable and were issued separately, but were purchased together.  The Company raised a total of $6.7 million 
from this offering, or approximately $6.0 million in net proceeds after deducting underwriting commissions of $470 thousand 
and other offering costs of $211 thousand.  

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On March 6, 2015, the Company closed a private placement offering of an aggregate of 370,993 immediately separable 
Units, which included 370,933 shares of the Company’s common stock, 278,200 Long-Term Warrants and 370,933 Short-
Term  Warrants  (the  “March  Offering”).  The  per  Unit  purchase  price  was  $12.50  for  outside  investors  and  $15.00  for 
Company insiders, and the exercise prices for the 15-month warrants and 5-year warrants were $0.60 and $0.65 per share, 
respectively. Also on March 6, 2015, the Company entered into a registration rights agreement with the purchasers, pursuant 
to which the Company agreed to file as many registration statements with the Securities and Exchange Commission (the 
“SEC”) as may be necessary to cover the resale of the shares of Company common stock issued in the offering, including 
those shares underlying the warrants, and to keep such registration statements effective for the terms defined therein. The 
Company raised a total of $4.7 million from this offering, or approximately $4.5 million in net proceeds after deducting 
offering costs of $200 thousand. The carrying amount of the warrant liability was $760 thousand as of December 31, 2015. 
Subsequent remeasurements of the warrant liability will be recorded to gain or loss on revaluation of the warrant liability in 
other income or expense. 

On May 22, 2015, the Company closed a private placement offering of an aggregate of 435,746 shares of the Company’s 
common stock and 217,873 warrants with a 12-month term (the “May Offering”). The purchase price for a share of Company 
common stock and related warrant was $15.75, and the exercise price for the warrants was $19.50 per share.  On May 18, 
2015, the Company entered into a registration rights agreement with the purchasers, pursuant to which the Company agreed 
to use best efforts to file as many registration statements with the SEC as may be necessary to cover the resale of the shares 
of  Company  common  stock  issued  in  the  offering,  including  those  shares  underlying  the  warrants,  and  to  keep  such 
registration statements effective for the terms defined therein. In connection with the May Offering, the Company agreed to 
enter into an additional definitive securities purchase agreement with the purchasers in the March Offering. In exchange for 
a  waiver  of  certain  pre-emptive  rights  granted  to  the  purchasers  in  the  March  Offering,  an  additional  635,000  shares  of 
Company common stock were issued to such purchasers (other than entities affiliated with the Company). The Company 
raised a total of $7.3 million from this offering, or approximately $6.4 million in net proceeds after deducting offering costs 
of $900 thousand. 

On October 27, 2015, pursuant to an underwriting agreement with Roth Capital Partners, LLC, the Company closed a 
public offering of (i) 492,000 shares of the Company’s common stock; and (ii) warrants to purchase up to 468,280 shares of 
the Company’s common stock with an exercise price of $5.00 per share. The shares of common stock and warrants were 
issued  separately.  Each  warrant  was  exercisable  immediately  upon  issuance  and  will  expire  60  months  from  the  date  of 
issuance. The price to the public in this offering was $5.00 per share of common stock and related warrant. The Company 
raised a total of $2.3 million from this offering, or approximately $1.9 million in net proceeds after deducting underwriting 
discounts and offering costs of $400 thousand.  

Stock Warrants 

At December 31, 2013, there were outstanding warrants to purchase 49,000 shares of common stock with an exercise 

price of $68.75 per share expiring on August 21, 2014.  

In July 2011, 139,520 warrants were issued in connection with our July 2011 registered direct financing. These warrants 
were  issued  with  an  exercise  price  of  $33.25  and  were  set  to  expire  on  July  5,  2016.  These  outstanding  warrants  were 
exercisable at December 31, 2015. During 2012, 1,200 of these warrants were exercised and the company received $30,000 
in cash for the warrants. See Note 8 for further details on these warrants. 

In March 2015, the Company issued 278,200 Long-Term Warrants and 370,933 Short-Term Warrants, with exercise 
prices of $16.25 and $15.00 per share, respectively. Both warrants were exercisable on or after September 6, 2015, six months 
from the date of issuance. These outstanding warrants were exercisable at December 31, 2015. See Note 8 for further details 
on these warrants. 

In May 2015, the Company issued 217,873 warrants with a 12-month term and an exercise price of $19.50 per share. The 
warrants became exercisable at any time on or after November 22, 2015, six months from the date of issuance, and will 
continue to be exercisable for one year thereafter. These outstanding warrants were exercisable at December 31, 2015. See 
Note 8 for further details on these warrants. 

In October 2015, the Company issued warrants to purchase up to 442,800 shares of the Company’s common stock with 
an exercise price of $5.00 per share. Each warrant was exercisable immediately upon issuance and will expire 60 months 
from the date of issuance. A price protection provision was included in such warrants, such that if the Company subsequently 
sells or otherwise disposes of Company common stock at a lower price per share than $5.00 or any securities exchangeable 
for common stock with a lower exercise price than $5.00, the exercise price of such warrants will be reduced to that lower 
price. See Note 8 for further details on these warrants. 

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The following table summarizes information about the Company’s warrants outstanding at December 31, 2015, 2014 

and 2013, and activity during the three years then ended.   

   Warrants 

(in thousands) 
Outstanding at December 31, 2012 ..........................................................................     
Warrants granted ...............................................................................................     
Warrants expired ...............................................................................................     
Warrants exercised ............................................................................................     
Outstanding at December 31, 2013 ..........................................................................     
Warrants granted ...............................................................................................     
Warrants expired ...............................................................................................     
Outstanding at December 31, 2014 ..........................................................................     
Warrants granted ...............................................................................................     
Warrants expired ...............................................................................................     
Outstanding at December 31, 2015 ..........................................................................     

Weighted- 
Average  
Exercise Price    
39.75  
40.75  
37.50  
37.50  
43.00  
39.00  
68.75  
35.23  
7.40  
39.00  
5.19  

448    $ 
1    $ 
(185)   $ 
(72)   $ 
192    $ 
55    $ 
(50)   $ 
197    $ 
1,317    $ 
(56)   $ 
1,458    $ 

NOTE 11. EQUITY-BASED COMPENSATION 

Equity Compensation Plans  

Prior to October 2007, the Company had two equity incentive plans in place: the 2002 Stock Option Plan and the 2005 
Stock Option Plan. In October 2007, the Company adopted the 2007 Omnibus Incentive Plan (the 2007 Plan) to provide for 
the granting of stock awards, such as stock options, unrestricted and restricted common stock, stock units, dividend equivalent 
rights, and stock appreciation rights to employees, directors and outside consultants, as determined by the board of directors. 
In conjunction with the adoption of the 2007 Plan, no further option awards may be granted from the 2002 or 2005 Stock 
Option Plans, and any option cancellations or expirations from the 2002 or 2005 Stock Option Plans may not be reissued. At 
the inception of the 2007 Plan, 40,000 shares were reserved for issuance under the 2007 Plan.   

For the years from 2009 to 2012, the number of shares of common stock authorized for issuance under the 2007 Plan 
increased annually in an amount equal to the lesser of (a) 40,000 shares or (b) 4% of the number of shares of the Company’s 
common stock outstanding on the last day of the preceding year or (c) such lesser number as determined by the board of 
directors.  Accordingly, an additional 40,000, 37,427, and 37,207 shares of common stock were authorized for issuance under 
the 2007 Plan in January 2012, 2011 and 2010, respectively. Beginning in 2013, the shareholders voted to remove the 40,000 
share cap and the 2007 Plan increases annually by 4% of the number of shares of the Company’s common stock outstanding 
on the last day of the preceding year. Accordingly, an additional 32,646 and 59,157 shares of common stock were authorized 
for  issuance  under  the  2007  Plan  in  January  2014  and  2013,  respectively.  On  March  30th,  2015,  the  company  filed  a 
registration statement to add an additional 82,461 shares to the 2007 Plan. As of December 31, 2015, there were 34,233 
shares available for future grant under the 2007 Plan. In January 2016 we added 139,449 shares to the Plan, per our evergreen 
provision.  

Under the terms of the 2007 Plan, the exercise price of incentive stock options may not be less than 100% of the fair 
value of the common stock on the date of grant and, if granted to an owner of more than 10% of the Company’s stock, then 
not less than 110%. Stock options granted under the 2007 Plan expire no later than ten years from the date of grant. Stock 
options granted to employees generally vest over four years, while options granted to directors and consultants typically vest 
over a shorter period, subject to continued service. All of the options granted prior to October 2007 include early exercise 
provisions that allow for full exercise of the option prior to the option vesting, subject to certain repurchase provisions. The 
Company issues new shares to satisfy option exercises under the plans.  

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Stock Based Compensation Summary 

The following table summarizes information about the Company’s stock options and restricted stock units outstanding 

at December 31, 2015, 2014 and 2013, and activity during the three years then ended: 

(in thousands, except years  
and per share data) 
Outstanding at December 31, 2012 ......................................     
Options granted .............................................................     
Options exercised ..........................................................     
Restricted stock units vested .........................................     
Options forfeited/cancelled ...........................................     
Outstanding at December 31, 2013 ......................................     
Options granted .............................................................     
Restricted stock units granted .......................................     
Options exercised ..........................................................     
Restricted stock units vested .........................................     
Options forfeited/cancelled ...........................................     
Outstanding at December 31, 2014 ......................................     
Options granted .............................................................     
Restricted stock units granted .......................................     
Options exercised ..........................................................     
Restricted stock units vested .........................................     
Options forfeited/cancelled ...........................................     
Restricted stock units cancelled ....................................     
Outstanding at December 31, 2015 ......................................     

Weighted-
Average 
Exercise 
Price 

Weighted-
Average 
Remaining 
Contractual 
Life (years) 

     Aggregate 
Intrinsic 
Value 

Options 

249     $ 
71     $ 
(10)   $ 
(10)   $ 
(13)   $ 
287       
68     $ 
3     $ 
(2)   $ 
(4)   $ 
(29)   $ 
323       
85     $ 
16     $ 
-    $ 
(6)   $ 
(28)   $ 
(2)   $ 
388     $ 

40.50       
34.75       
11.00       
—      
42.50       

22.50       
—      
14.00       
—      
36.50       

11.20       
—      
—      
—      
30.58       
—      
32.03       

6.2    $ 

19   

Vested and expected to vest at December 31, 2015 .............     

379     $ 

32.35       

6.1    $ 

19   

Vested at December 31, 2015 ..............................................     

294     $ 

37.63       

5.2    $ 

Exercisable at December 31, 2015 .......................................     

294     $ 

37.63       

5.2    $ 

2   

2   

For  options  that  have  a  quoted  market  price  in  excess  of  the  exercise  price  (“in-the-money  options”),  the  aggregate 
intrinsic value is calculated as the difference between the exercise price of the underlying stock option awards and the closing 
market price of the Company’s common stock as quoted on the NYSE MKT as of December 31, 2015. The Company received 
no cash payments for the exercise of stock options during the year ended December 31, 2015. The Company received $34 
thousand and $114 thousand during the years ended December 31, 2014 and 2013, respectively. The aggregate intrinsic value 
of stock option awards exercised was $4 thousand, $32 thousand, and $261 thousand for the years ended December 31, 2015, 
2014 and 2013, respectively, as determined at the date of option exercise.  

As of December 31, 2015, total unrecognized compensation cost related to unvested stock options and restricted stock 
units was $956 thousand. This amount is expected to be recognized as stock-based compensation expense in the Company’s 
consolidated statements of operations and comprehensive loss over the remaining weighted average vesting period of 2.17 
years. 

Stock Option Awards to Employees and Directors  

The Company grants options to purchase common stock to its employees and directors at prices equal to or greater than 
the market value of the stock on the dates the options are granted. The Company has estimated the value of stock option 
awards as of the date of grant by applying the Black-Scholes-Merton option pricing model using the single-option valuation 
approach. The application of this valuation model involves assumptions that are judgmental and subjective in nature. See 
Note 2 for a description of the accounting policies that the Company applies to value its stock-based awards. 

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During the years ended December 31, 2015, 2014 and 2013, the Company granted options to employees and directors 

to purchase an aggregate of 59,000, 52,000 and 64,000 shares of common stock, respectively.  

The weighted average assumptions used in determining the value of options granted and a summary of the methodology 

applied to develop each assumption are as follows:  

Assumption 
Expected price volatility ........................................................     
Expected term (in years) .......................................................     
Risk-free interest rate ............................................................     
Dividend yield .......................................................................     
Weighted-average fair value of options granted during the 

2015 

Year Ended December 31,  
2014 

2013 

77.22 %     
6.8        
1.76 %     
0.00 %     

76.88 %     
6.5        
2.06 %     
0.00 %     

80.15% 
5.1  
1.13% 
0.00% 

period ..................................................................................   $ 

7.35      $ 

15.25      $ 

23.00   

Expected Price Volatility—This is a measure of the amount by which the stock price has fluctuated or is expected to 
fluctuate. The computation of expected volatility was based on the historical volatility of our own stock and comparable 
companies from a representative peer group selected based on industry and market capitalization data.  

Expected Term—This is the period of time over which the options granted are expected to remain outstanding. The 

expected life assumption is based on the Company’s historical data.  

Risk-Free  Interest  Rate—This  is  the  U.S.  Treasury  rate  for  the  week  of  the  grant  having  a  term  approximating  the 

expected life of the option.  

Dividend Yield—We have not made any dividend payments nor do we have plans to pay dividends in the foreseeable 

future.  

Forfeitures are estimated at the time of grant and reduce compensation expense ratably over the vesting period. This 
estimate is adjusted periodically based on the extent to which actual forfeitures differ, or are expected to differ, from the 
previous estimate.  

Additionally, during the years ended December 31, 2015 and 2014, the Company issued 16,000 and 2,000 shares of 
common stock to employees, respectively. The Company did not issue any shares of common stock to its employees during 
the year ended 2013.  

For the years ended December 31, 2015, 2014 and 2013, we recognized stock-based compensation expense of $1,193 

thousand, $853 thousand and $921 thousand, respectively, for option awards to employees and directors.  

Stock-Based Awards to Non-Employees  

During the years ended December 31, 2015, 2014 and 2013, the Company granted options to purchase an aggregate of 
27,000, 14,000, and 7,000 shares of common stock, respectively, to non-employees in exchange for advisory and consulting 
services. The stock options are recorded at their fair value on the measurement date and recognized over the respective service 
or vesting period. The fair value of the stock options granted was calculated using the Black-Scholes-Merton option pricing 
model based upon the following assumptions: 

Assumption 
Expected price volatility ........................................................     
Expected term (in years) .......................................................     
Risk-free interest rate ............................................................     
Dividend yield .......................................................................     
Weighted-average fair value of options granted during the 

2015 

Year Ended December 31,  
2014 

2013 

83.77 %     
9.6        
2.18 %     
0.00 %     

79.10 %     
8.6        
2.28 %     
0.00 %     

78.89% 
8.5  
2.75% 
0.00% 

period ..................................................................................   $ 

7.15      $ 

15.25      $ 

23.75   

In addition, the Company granted restricted stock to non-employees totaling 500, 600 and 2,000 shares of common stock 

in the years ended December 31, 2015, 2014 and 2013, respectively, in exchange for advisory and consulting services.  

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For the years ended December 31, 2015, 2014 and 2013, the Company recognized stock-based compensation expense 
of $188 thousand, $189 thousand and $97 thousand, respectively, related to non-employee options and restricted stock grants.  

Summary of Stock-Based Compensation Expense 

A summary of the stock-based compensation expense included in results of operations for the option and stock awards 

discussed above is as follows: 

(in thousands) 
Research and development .........................................    $ 
General and administrative .........................................      
Total stock-based compensation expense ...................    $ 

2015 

Year Ended December 31,  
2014 

2013 

449     $ 
933       
1,382     $ 

376     $ 
666       
1,042     $ 

381   
637   
1,018   

Since the Company has operating losses and net operating loss carryforwards, there are no tax benefits associated with 

stock-based compensation expense. 

NOTE 12. LICENSE, COLLABORATION AND DISTRIBUTION AGREEMENTS  

Galderma 

On March 25, 2009, the Company entered into a collaboration and license agreement with Galderma S.A. to develop 
and  commercialize  the  Company’s  Aganocide  compounds,  which  covers  acne,  impetigo  and  potentially  other  major 
dermatological conditions.  The Company amended this agreement in December 2009 and again in December 2010.  Based 
on the Impetigo Phase 2a clinical trial results, in December 2010, Galderma S.A. exercised the option to continue with the 
development of an impetigo treatment and initiated a Phase 2b study.  In November 2013, the Company announced that the 
auriclosene Phase 2b clinical study regarding the treatment of impetigo had been completed. While the study showed that 
auriclosene is safe and well tolerated, it did not meet its primary clinical endpoint. Knowledge gained from two previous 
impetigo  studies  is  expected  to  lead  to  both  improvements  in  the  clinical  study  protocol  and  an  optimized  auriclosene 
formulation if the program moves forward. 

Galderma  paid  NovaBay  certain  upfront  fees,  ongoing  fees,  reimbursements,  and  milestone  payments  related  to 
achieving  development  and  commercialization  of  its  Aganocide  compounds.  If  products  are  commercialized  under  the 
agreement, NovaBay’s royalties will escalate as sales increase. The Company received a $1.0 million upfront technology 
access fee payment in the first quarter of 2009 and a $3.25 million continuation fee and a $500,000 fee to expand the license 
to include the Asia-Pacific Territory in December 2010. These fees were recorded as deferred revenues and recognized as 
earned on a straight-line basis over the Company’s expected performance period. The initial upfront technology access fee 
was recognized over the initial 20 month funding term of the agreement through October 2010, and the continuation and 
license fees were recognized over the additional three year funding term of the agreement through November 2013. 

Revenue has been recognized under the Galderma agreement as follows: 

(in thousands) 
Amortization of upfront technology access fee, continuation 

fee and license fee ................................................................   $ 
On-going Research and Development ....................................     
Materials, Equipment, and Contract Study Costs ...................     
  $ 

2015 

Year Ended December 31, 
2014 

2013 

--    $ 
—      
—      
--    $ 

1     $ 
—       
—       
1     $ 

945   
1,228   
393   
2,566   

The Company had deferred revenue balances of $0, $0 and $1 thousand, respectively, at December 31, 2015, 2014 and 
2013, related to the Galderma agreement, which consisted of the unamortized balances on the upfront technology and access 
fee and the continuation and license fee and support for ongoing research and development. As of December 31, 2015, the 
Company has earned $4.25 million in milestone payments. For the year ended December 31, 2015, the Company has not 
earned or received any royalty payments under the Galderma agreement. 

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Virbac 

In April 2012, the Company entered into a feasibility and option agreement with Virbac, a global animal health company, 
for the development and potential commercialization of Aganocides for a number of veterinary uses for companion animals. 
Under the terms of the agreement, NovaBay received an upfront payment and is entitled to additional support for research 
and development. The Company will conduct veterinary studies using NovaBay’s Aganocide compounds to assess feasibility 
for treating several veterinary indications. 

In April 2013, the option was exercised and the Company entered into a collaboration and license agreement with Virbac. 
Under this new agreement, Virbac acquired exclusive worldwide rights to develop the Company’s proprietary compound, 
auriclosene (NVC-422), for global veterinary markets for companion animals.  The Company received an option exercise fee 
and may receive future development and pre-commercial milestone payments as a result of the collaboration. The Company 
also  expects  to  receive  royalties  on  the  sale  of  any  commercial  products  in  the  companion  animal  field.  Virbac’s  option 
exercise follows its extensive testing of auriclosene for veterinary uses during the 12-month option period. The Company is 
recognizing the option exercise fee over its expected performance period of 10 years based on actual sales during this period. 

Revenue has been recognized under the agreement as follows: 

(in thousands) 
Amortization of upfront technology access fee, continuation 

fee and license fee ................................................................   $ 
On-going Research and Development ....................................     
Materials, Equipment, and Contract Study Costs ...................     
  $ 

2015 

Year Ended December 31, 
2014 

2013 

—    $ 
—      
—      
—    $ 

—     $ 
—       
38       
38     $ 

42  
87  
8  
137   

The  Company  had  deferred  revenue  balances  of  $246  thousand,  $246  thousand  and  $246  thousand,  respectively,  at 
December 31, 2015, 2014 and 2013, related to this agreement, which consisted of the unamortized balances on the upfront 
technology and access fee and the support for ongoing research and development. 

NeutroPhase Distribution Agreements 

In  January  2012,  the  Company  entered  into  a  distribution  agreement  with  Pioneer  Pharma  Co.,  Ltd.  (“Pioneer”),  a 
Shanghai-based  company  that  markets  high-end  pharmaceutical  products  into  China,  for  the  commercialization  of 
NeutroPhase in this territory. Under the terms of the agreement, NovaBay received an upfront payment of $312,500. NovaBay 
also received $312,500 in January 2013, related to the submission of the first marketing approval for the product to the CFDA 
(formerly  the  SFDA,  State  Food  and  Drug  Administration),  which  was  submitted  in  December  2012.  The  distribution 
agreement provides that Pioneer is entitled to receive cumulative purchase discounts of up to $500,000 upon the purchase of 
NeutroPhase  product.  The  deferred  revenue  will  be  recognized  as  the  purchase  discounts  are  earned,  with  the  remaining 
deferred  revenue  recognized  ratably  over  the  product  distribution  period.  During  the  year  ended  December  31,  2014, 
NovaBay received $625,000 upon receipt of a marketing approval of the product from the CFDA.  

In September 2012, the Company entered into two agreements with Pioneer: (1) an international distribution agreement 
(“Distribution Agreement”) and (2) a unit purchase agreement (“Purchase Agreement”). These agreements were combined 
and accounted for as one arrangement with one unit of accounting for revenue recognition purposes. 

Pursuant to the terms of the Distribution Agreement, Pioneer has the right to distribute NeutroPhase, upon a marketing 
approval from a Regulatory Authority, in certain territories in Asia (other than China). Upon execution of the Distribution 
Agreement, we received an upfront payment, which was recorded as deferred revenue. Pioneer is also obligated to make 
certain additional payments to us upon receipt of the marketing approval. The Distribution Agreement further provides that 
Pioneer is entitled to a cumulative purchase discount not to exceed $500,000 upon the purchase of NeutroPhase product, 
payable in NovaBay unregistered restricted common stock. 

Pursuant to the Purchase Agreement, we also received $2.5 million from Pioneer for the purchase of restricted units 
(comprising one share of common stock and a warrant for the purchase of one share of common stock). The unit purchase 
was completed in two tranches: (1) 800,000 units in September 2012; and (2) 1,200,000 units in October 2012, with both 
tranches at a purchase price of $1.25 per unit. The fair value of the total units sold was $3.5 million, based upon the trading 
price of our common stock on the dates the units were purchased and the fair value of the warrants based on the Black-
Scholes Merton option pricing model. Because the aggregate fair value of the units on the dates of purchase exceeded the 

54 

 
  
  
   
  
  
  
  
  
    
    
  
  
  
  
  
  
  
  
$2.5 million in proceeds received from the unit purchase by approximately $1 million, we reallocated $600,000 from deferred 
revenue to stockholders’ equity as consideration for the purchase of the units.  

In December 2013, the Company announced it had expanded its NeutroPhase commercial partnership agreement with 
Pioneer.  The  expanded  agreement  includes  licensing  rights  to  two  new  products,  Avenova  and  CelleRx,  which  were 
developed internally by NovaBay. The expanded partnership agreement covers the commercialization and distribution of 
these products in China and 11 countries in Southeast Asia.  

Revenue has been recognized under these agreements as follows: 

(in thousands) 

2015 

Year Ended December 31, 
2014 

2013 

Amortization of upfront technology access fee ......................   $ 
On-going Research and Development ....................................     
  $ 

26    $ 
--      
26    $ 

63     $ 
55       
118     $ 

62   
148   
210  

The Company had deferred revenue balances of $2.1 million, $2.2 million, and $1.6 million, respectively, at December 
31, 2015, 2014 and 2013, related to these agreements, which consisted of the unamortized balances on the upfront technology 
and access fee and the support for ongoing research and development. 

Avenova Distribution Agreements 

In November 2014, the Company signed a nationwide distribution agreement for its Avenova product with McKesson 
Corporation (“McKesson”). The agreement is part of the Company’s commercialization strategy. McKesson makes Avenova 
widely available in local pharmacies and major retail chains across the U.S., such as Wal-Mart, Costco, CVS and Target. 
During the year ended December 31, 2014, the Company earned $4,000 in sales revenue related to the distribution agreement 
with McKesson. 

In  January  2015,  the  Company  signed  a  nationwide  distribution  agreement  with  Cardinal  Health.  In  April  2015,  the 

Company signed a nationwide distribution agreement with AmerisourceBergen to market Avenova. 

NOTE 13. EMPLOYEE BENEFIT PLAN  

We have a 401(k) plan covering all eligible employees. We are not required to contribute to the plan and have made no 

contributions through December 31, 2015. 

NOTE 14. INCOME TAXES  

The federal and state income tax provision is summarized as follows (in thousands): 

(in thousands) 
Current 

Federal ................................................................   $ 
State ....................................................................     
Other ...................................................................     
Total current tax expense ...........................................      

Deferred 

Federal ................................................................     
State ....................................................................     
Other ...................................................................     
Total deferred tax expense .........................................      

Income tax provision ..................................................    $ 

2015 

Year Ending December 31 
2014 

2013 

—    $ 
1.6      
—      
1.6      

—      
—      
—      
—      

1.6    $ 

—    $ 
1.6      
—      
1.6      

—      
—      
—      
—      

1.6    $ 

—  
1.6  
—  
1.6  

—  
—  
—  
—  

1.6  

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Deferred income taxes reflect the net tax effects of (a) temporary differences between the carrying amounts of assets and 
liabilities for financial reporting purposes and the amounts used for income tax purposes, and (b) operating losses and tax 
credit carryforwards. 

The tax effects of significant items comprising the Company's deferred taxes as of December 31 are as follows: 

(in thousands) 
Deferred tax assets: 

December 31 

2015 

2014 

Net operating losses ......................................................................................   $ 
Accruals ........................................................................................................     
Deferred revenue ..........................................................................................     
Stock options ................................................................................................     
Other deferred tax assets ..............................................................................     
Total deferred tax assets .............................................................     

31,464     $ 
403       
954       
1,558       
652       
35,031       

Deferred tax liabilities: 

Property and equipment ................................................................................     
Total deferred tax liabilities ........................................................     

(28)     
(28)     

Valuation allowance .........................................................................................     
Net deferred taxes ............................................................................................   $ 

(35,003)     
—    $ 

24,213   
246   
717   
1,329   
464   
26,969   

(67) 
(67) 

(26,902) 
—  

The Company records the tax benefit of net operating loss carryforwards and temporary differences as an asset to the 
extent that management assesses that realization is "more likely than not." Realization of the future tax benefits is dependent 
on the Company's ability to generate sufficient taxable income within the carryforward period. Because of the Company's 
recent history of operating losses, management believes that recognition of the deferred tax assets is currently not likely to 
be realized and, accordingly, has provided a valuation allowance. 

The valuation allowance increased by the following amounts (in thousands):  

2015 

2014 

2013 

$ 

8,101    $ 

6,286    $

6,096   

In accordance with ASC 718 Compensation – Stock Compensation, the Company has excluded from deferred tax assets 
benefits attributable to employee stock option exercises. Therefore, these amounts are not included in gross or net deferred 
tax assets. As of December 31, 2015, approximately $1.1 million of federal and $0.8 million of state net operating loss is 
attributable to stock-based compensation deductions in excess of book expense. The benefit of the tax deduction related to 
these options will be credited to stockholders' equity when they reduce cash taxes payable. 

Net operating loss and tax credit carryforwards as of December 31, 2015, are as follows (in thousands):  

Net operating losses, federal ..............................................................   $ 
Net operating losses, state ..................................................................   $ 
Tax credits, federal .............................................................................   $ 
Tax credits, state ................................................................................   $ 

Amount 

80,622      
77,141      
1,274      
256     

Expiration  
Years 
 2024 - 2035 
 2016 - 2035 
 2031 - 2034 
do not expire 

Under U.S. federal tax law, the amount and availability of tax benefits are subject to a variety of interpretations and 
restrictive tests. Utilization of the net operating loss (NOL) carryforwards may be subject to a substantial annual limitation 
due to ownership changes that have occurred previously or that could occur in the future, as provided by Section 382 of the 
Internal Revenue Code of 1986, and similar state provisions. Ownership changes may limit the amount of NOL carryforwards 
that can be utilized annually to offset future taxable income and tax, respectively. In general, an ownership change, as defined 
by Section 382, results from transactions increasing the ownership of certain shareholders or public groups in the stock of a 
corporation by more than 50 percentage points over a three-year period. Since the Company’s formation, the Company has 
raised capital through the issuance of capital stock on two occasions which, combined with the purchasing shareholders’ 
subsequent disposition of those shares, may have resulted in one or more changes of control, as defined by Section 382. The 

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Company has not currently completed a study to assess whether any change of control has occurred, or whether there have 
been multiple changes of control since the Company’s formation, due to the significant complexity and cost associated with 
the study. If the Company has experienced a change of control at any time since its formation, its NOL carryforwards and 
tax credits may not be available, or their utilization could be subject to an annual limitation under Section 382. A full valuation 
allowance has been provided against the Company’s NOL carryforwards, and if an adjustment is required, this adjustment 
would be offset by an adjustment to the valuation allowance. Accordingly, there would be no impact on the consolidated 
balance sheet or statement of operations if an adjustment is required. 

The effective tax rate of the Company's provision (benefit) for income taxes differs from the federal statutory rate as 

follows: 

(in thousands) 

2015 

Year Ending December 31 
2014 

2013 

Income tax provision (benefit) at federal statutory rate ...   $ 
State tax ............................................................................     
ISO-related expense for GAAP ........................................     
Change in valuation allowance ........................................     
Revaluation of warrant liability .......................................     
Tax credits ........................................................................     
Other ................................................................................     
Total .................................................................................   $ 

(6,439 )   $ 
(1,060 )     
164       
8,101       
(731 )     
(123 )     
90       
2     $ 

(5,154)   $ 
(818)     
144       
6,286       
(565)     
(44)     
153       
2     $ 

(5,425 ) 
(836 ) 
178   
6,095   
189   
(285 ) 
86   
2   

Uncertain Income Tax Positions 

The Company adopted the provisions of ASC 740-10, Accounting for Uncertainty in Income Taxes, on January 1, 2007. 
There was no impact on our consolidated financial position, results of operations and cash flows as a result of adoption. A 
reconciliation of the beginning and ending balances of the unrecognized tax benefits during the years ended December 31, 
2015 and 2014 is as follows: 

(in thousands) 
Unrecognized benefit - beginning of period ....................................................   $ 
Gross increases - current period tax positions ..................................................     
Unrecognized benefit - end of period ...............................................................   $ 

Year ended December 31, 
2014 
2015 

881     $ 
76       
957     $ 

866   
15   
881   

Our policy will be to recognize interest and penalties related to income taxes as a component of income tax expense. We 
are subject to income tax examinations for U.S. incomes taxes and state income taxes from 2004 forward. We do not anticipate 
that total unrecognized tax benefits will significantly change in the next 12 months.  

Net Operating Losses and Tax Credit Carryforwards 

As of December 31, 2015, we had net operating loss carryforwards for federal and state income tax purposes of $80.6 
million  and  $77.1  million,  respectively.  If  not  utilized,  the  federal  and  state  net  operating  loss  carryforwards  will  begin 
expiring at various dates between 2016 and 2035. As of December 31, 2015, we also had tax credit carryforwards for federal 
income tax purposes of $1,274,000 and $256,000 for state tax purposes. If not utilized, the federal tax credits will begin 
expiring in 2031. The state tax credits have an indefinite carryover period.  

Current  federal  and  California  tax  laws  include  substantial  restrictions  on  the  utilization  of  net  operating  loss 
carryforwards in the event of an ownership change of a corporation. Accordingly, our ability to utilize net operating loss 
carryforwards  may  be  limited  as  a  result  of  such  ownership  changes.  Such  a  limitation  could  result  in  the  expiration  of 
carryforwards before they are utilized. 

57 

 
  
  
  
  
  
  
    
    
  
  
    
        
       
    
  
  
  
  
  
  
  
    
  
  
  
  
  
   
 
 
NOTE 15. SUBSEQUENT EVENTS  

In December 2015 and January 2016, we entered into a series of agreements pursuant to a loan (the “Loan”) facilitated 
by China Kington Asset Management Co. Ltd. (“China Kington”). In connection with the Loan, we issued five (5) promissory 
notes (the “Notes”) payable to Mr. Mark Sieczkarek, the Gail J. Maderis Revocable Trust, Dr. T. Alex McPherson, Mr. Jian 
Ping Fu, and Pioneer Pharma (Singapore) Pte. Ltd. (“Pioneer Pharma”) (collectively, the “Lenders”), loaning us an aggregate 
of $3,020,000. Specifically, Mr. Sieczkarek, Chairman of the Board and Interim President and Chief Executive Officer of the 
Company, loaned us $199,000; the Gail J. Maderis Revocable Trust, on behalf of Ms. Maderis, a Director of the Company, 
loaned us $71,000; Dr. McPherson, a Director of the Company, loaned us $20,000; Pioneer Pharma loaned us $1,365,000; 
and Mr. Fu loaned us $1,365,000. All Notes were issued on December 30, 2015 except the Note payable to Mr. Fu, which 
was issued on January 12, 2016 upon receipt of all funds. The loan has a three-year term with no pre-payment penalty. 

In February 2016, we entered into three securities purchase agreements (the “Purchase Agreements”) for the sale of an 
aggregate of 1,518,567 shares of the Company’s common stock (the “Common Stock”) to accredited investors for a total of 
$2,831,000. We entered into the first purchase agreement with Mr. Jian Ping Fu (the “Fu Agreement”), pursuant to which the 
Company agreed to issue and sell to Mr. Fu 696,590 shares of Common Stock, at a per share price of $1.81, which was a five 
percent (5%) discount to the closing price of the Common Stock on February 16, 2016, the date of the Fu Agreement. We 
entered into the second purchase agreement with Pioneer Pharma (the “Pioneer Agreement”), pursuant to which we agreed 
to issue and sell to Pioneer, Pharma 696,590 shares of Common Stock, at a per share price of $1.91, which was the closing 
price of the Common Stock on February 16, 2016 with no discount. We entered into a third purchase agreement with Mark 
M. Sieczkarek (the “Sieczkarek Agreement”), pursuant to which the Company agreed to issue and sell to Mr. Sieczkarek 
125,387  shares  of  Common  Stock,  at  a  per  share  price  of  $1.91,  which  was  the  closing  price  of  the  Common  Stock  on 
February 16, 2016 with no discount. The Common Stock issued by the Company pursuant to the Purchase Agreements has 
not been registered under the Securities Act and may not be offered or sold in the United States absent registration or an 
applicable exemption from registration requirements. 

58 

 
    
  
 
 
ITEM 9.  CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND 

FINANCIAL DISCLOSURE 

None. 

ITEM 9A.  CONTROLS AND PROCEDURES 

Evaluation of Disclosure Controls and Procedures 

As of the end of the period covered by this report, we carried out an evaluation, under the supervision and with the 
participation of our management, including our Chief Executive Officer and Chief Financial Officer, of the effectiveness of 
our  disclosure  controls  and  procedures  pursuant  to  Rule  13a-15  and  15d-15  of  the  Securities  Exchange  Act  of  1934,  as 
amended  (the  Exchange  Act).  Based  upon  that  evaluation,  our  Chief  Executive  Officer  and  our  Chief  Financial  Officer 
concluded  that  our  disclosure  controls  and  procedures  were  effective  to  ensure,  at  the  reasonable  assurance  level,  that 
information required to be disclosed by us in the reports that we file or submit under the Exchange Act is recorded, processed, 
summarized and reported within the time periods specified in the SEC’s rules and forms and were effective in ensuring that 
information required to be disclosed by us in the reports that we file or submit under the Exchange Act was accumulated and 
communicated to our management, including our Chief Executive Officer and Chief Financial Officer, as appropriate, to 
allow timely decisions regarding required disclosure. 

A control system, no matter how well conceived and operated, can provide only reasonable, not absolute, assurance that 
the objectives of the control system are met. Further, the design of a control system must reflect the fact that there are resource 
constraints, and the benefits of controls must be considered relative to their costs. Assessing the costs and benefits of such 
controls and procedures necessarily involves the exercise of judgment by management. Because of the inherent limitations 
in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, 
if any, have been detected. Our Chief Executive Officer and our Chief Financial Officer concluded that our disclosure controls 
and procedures were effective at the reasonable assurance level. 

Management’s Report on Internal Control over Financial Reporting. 

Our management is responsible for establishing and maintaining adequate internal control over financial reporting, as 
such term is defined in Exchange Act Rules 13a-15(f) and 15d-15(f). Under the supervision and with the participation of our 
management, including our principal executive officer and our principal financial officer, we conducted an evaluation of the 
effectiveness of our internal control over financial reporting as of December 31, 2015.  Our management utilized the criteria 
set forth in “Internal Control-Integrated Framework (2013)” issued by the Committee of Sponsoring Organizations of the 
Treadway  Commission  to  conduct  an  assessment  of  the  effectiveness  of  our  internal  control  over  financial  reporting  as 
of December 31, 2015. Our management has concluded that, as of December 31, 2015, our internal control over financial 
reporting was effective based on these criteria. 

Changes in Internal Control Over Financial Reporting 

During  the  fourth  quarter  of  2015,  there  were  no  changes  in  our  internal  control  over  financial  reporting  which  has 

materially affected, or are reasonably likely to materially affect, our internal control over financial reporting. 

ITEM 9B.  OTHER INFORMATION 

None. 

59 

 
  
  
  
  
  
  
  
  
  
  
  
  
 
 
PART III 

ITEM 10.  DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE 

The  information  required  by  this  item  will  be  included  in  our  Proxy  Statement  for  the  2016  Annual  Meeting  of 

Stockholders (the “2016 Proxy Statement”) and is incorporated herein by reference. 

ITEM 11.  EXECUTIVE COMPENSATION 

The  information  required  by  this  item  will  be  included  in  the  2016  Proxy  Statement  and  is  incorporated  herein  by 

reference. 

ITEM 12.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND 

RELATED STOCKHOLDER MATTERS 

The  information  required  by  this  item  will  be  included  in  the  2016  Proxy  Statement  and  is  incorporated  herein  by 

reference. 

ITEM 13.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR 

INDEPENDENCE 

The  information  required  by  this  item  will  be  included  in  the  2016  Proxy  Statement  and  is  incorporated  herein  by 

reference. 

ITEM 14.  PRINCIPAL ACCOUNTANT FEES AND SERVICES 

The  information  required  by  this  item  will  be  included  in  the  2016  Proxy  Statement  and  is  incorporated  herein  by 

reference. 

ITEM 15.  EXHIBITS, FINANCIAL STATEMENT SCHEDULES 

(a) Documents filed as part of this report: 

PART IV 

(1) Financial Statements. The financial statements listed in the Index for Item 8 hereof are filed as part of this 

report. 

(2) Financial  Statement  Schedules.  All  schedules  have  been  omitted  because  they  are  not  required  or  the 

required information is included in our consolidated financial statements and notes thereto. 

(3) Exhibits. See the Exhibit Index which follows the signature page of this report, which is incorporated herein 

by reference. 

60 

 
  
  
   
  
  
  
  
  
  
  
  
  
  
  
  
 
 
SIGNATURES 

Pursuant  to  the  requirements  of  Section 13  or  15(d) of  the  Securities  Exchange Act  of  1934,  the  registrant  has duly 

caused this report on Form 10-K to be signed on its behalf by the undersigned, thereunto duly authorized. 

Date: March 3, 2016 

By: 

/s/   Mark M. Sieczkarek  

Director and Interim Chief Executive Officer 

POWER OF ATTORNEY 

We, the undersigned officers and directors of NovaBay Pharmaceuticals, Inc., do hereby constitute and appoint Mark M. 
Sieczkarek and Thomas J. Paulson, and each of them, our true and lawful attorneys-in-fact and agents, each with full power 
of substitution and resubstitution, for him and in his name, place and stead, in any and all capacities, to sign any and all 
amendments to this report, and to file the same, with exhibits thereto, and other documents in connection therewith, with the 
Securities  and  Exchange  Commission,  granting  unto  said  attorneys-in-fact  and  agents,  and  each  of  them,  full  power  and 
authority to do and perform each and every act and thing requisite or necessary to be done in and about the premises, as fully 
to all intents and purposes as he might or could do in person, hereby, ratifying and confirming all that each of said attorneys-
in-fact and agents, or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof. 

Pursuant to the requirements of the Securities Exchange Act of 1934, this report on Form 10-K has been signed below 

by the following persons on behalf of the registrant in the capacities and on the dates indicated: 

Signature 

Title 

/s/ MARK M. SIECZKAREK  
Mark M. Sieczkarek  

  Chairman of the Board and Interim Chief  
  Executive Officer (principal executive officer) 

/s/ THOMAS PAULSON 
Thomas J. Paulson 

/s/ PAUL FREIMAN 
Paul E. Freiman 

/s/ ALEX MCPHERSON 
Alex McPherson, MD, Ph.D 

/s/ GAIL MADERIS 
Gail Maderis 

/s/ MASSIMO RADAELLI 
Massimo Radaelli, Ph.D 

/s/ LI XINZHOU 
LI Xinzhou 

/s/ WU MIJIA 
WU Mijia 

/s/ LIU XIAOYAN 
LIU Xiaoyan 

  Chief Financial Officer and Treasurer (principal   
  financial and accounting officer) 

  Director 

  Director 

  Director 

  Director 

  Director 

  Director 

  Director 

61 

Date

March 3, 2016

March 3, 2016

March 3, 2016

March 3, 2016

March 3, 2016

March 3, 2016

March 3, 2016

March 3, 2016

March 3, 2016

 
  
  
   
   
   
   
   
   
   
  
  
  
  
  
  
   
     
     
  
     
   
     
     
     
   
     
     
  
    
     
   
     
     
  
    
     
   
     
     
  
    
     
   
     
     
  
    
     
   
     
     
  
    
     
   
     
     
  
    
     
   
     
     
  
     
     
  
  
 
 
EXHIBIT INDEX 

Exhibit 
Number 
2.1 

3.1 

3.2 

3.3 

3.4 

3.5 
4.1 

4.2 
4.3 

4.4 

4.5 

4.6 

4.7 
4.8 

4.9 

4.10 

4.11 
4.12 

4.13 

4.14 

4.15 

  Exhibit Description 
Agreement and Plan of Merger of NovaBay 
Pharmaceuticals, Inc. (a California 
corporation) and NovaBay Pharmaceuticals, 
Inc. (a Delaware Corporation)  
Amended and Restated Certificate of 
Incorporation of NovaBay Pharmaceuticals, 
Inc.  
Certificate of Amendment of Amended and 
Restated Certificate of Incorporation of 
NovaBay Pharmaceuticals, Inc.  
Certificate of Amendment of Amended and 
Restated Certificate of Incorporation of 
NovaBay Pharmaceuticals, Inc.  
Certificate of Amendment of Amended and 
Restated Certificate of Incorporation of 
NovaBay Pharmaceuticals, Inc. 
Bylaws  
Form of Warrant issued in August 2009 
offering. 
Form of Warrant issued in July 2011 offering 
Form of Warrant issued in December 2012 
offering 
Form of Warrant issued in March 2014 
offering 
Form of Warrant issued in March 2015 
Offering (issued with 15-month term) 
Form of Warrant issued in March 2015 
Offering (issued with 5-year term) 
Form of Warrant issued in May 2015 offering 
Form of Warrant issued in October 2015 
offering 
Registration Rights Agreement (between the 
Company, Pioneer Pharma (Singapore) Pte. 
Ltd., and Anson Investments Master Fund LP,
et al.) 
Registration Rights Agreement (between the 
Company, China Kington Investment Co. 
Ltd. and Dr. Dean Rider) 
Promissory Note payable to Mark Sieczkarek 
Promissory Note payable to The Gail J. 
Maderis Revocable Trust 
Promissory Note payable to T. Alex 
McPherson 
Promissory Note payable to Pioneer Pharma 
(Singapore) Pte. Ltd. 
Promissory Note payable to Jian Ping Fu 

Incorporation by Reference 

 Form 
S-3 

 File Number 
333-159917 

Exhibit/ 
Form 8-K Item  
Reference 
2.1 

Filed 
Herewith 

 Filing Date 
7/1/2010 

8-K 

001-33678 

8-K 

001-33678 

8-K 

001-33678 

8-K 

001-33678 

8-K 
8-K 

8-K 
8-K 

8-K 

8-K 

8-K 

10-Q 
8-K 

001-33678 
001-33678 

001-33678 
001-33678 

001-33678 

001-33678 

001-33678 

001-33678 
001-33678 

3.1 

3.1 

3.1 

3.1 

3.2 
4.3 

4.4 
4.1 

4.1 

4.2 

4.3 

4.7 
4.1 

6/29/2010 

6/04/2014 

10/02/2015     

12/21/2015     

6/29/2010 
8/21/2009 

10/27/2015     
12/6/2012 

3/20/2014 

10/27/2015     

10/27/2015     

8/13/2015 
10/27/2015     

8-K 

001-33678 

10.2 

3/9/2015 

10-Q 

001-33678 

4.9 

8/13/2015 

8-K 
8-K 

8-K 

8-K 

8-K 

001-33678 
001-33678 

001-33678 

001-33678 

001-33678 

10.1 
10.2 

10.3 

10.4 

10.1 

1/06/2016 
1/06/2016 

1/06/2016 

1/06/2016 

1/14/2016 

62 

 
  
  
  
  
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
 
 
 
Exhibit 
Number 
4.16 

4.17 

10.1+ 

  Exhibit Description 

Collateral Agency and Intercreditor 
Agreement (among China Kington Asset 
Management Co. Ltd. and the lenders named 
therein) 
Security Agreement (between the Company 
and China Kington Asset Management Co. 
Ltd.) 
Indemnity Agreement (Form of Indemnity 
Agreement between the Company and its 
Directors and Officers) 

10.2+  NovaCal Pharmaceuticals, Inc. 2002 Stock 

Option Plan 

10.3+  NovaCal Pharmaceuticals, Inc. 2005 Stock 

Option Plan  

10.4+  NovaBay Pharmaceuticals, Inc. 2007 

Omnibus Incentive Plan (as amended and 
restated) 

10.5+  NovaBay Pharmaceuticals, Inc. 2007 

Omnibus Incentive Plan (Form Agreements 
to the 2007 Omnibus Incentive Plan)  

Long Term Strategic Bonus for Executives 

10.6+  Executive Officer Cash Bonus Structure  
10.7 
10.8+  Non-Employee Director Compensation Plan 
10.9+ 
2013 Bonuses for Named Executive Officers  
10.10+  2014 Bonuses for Named Executive Officers 
10.11+  Separation Agreement (by and between the 

Company and Ramin “Ron” Najafi) 
10.12+  Executive Employment Agreement 

(Employment Agreement of Mark M. 
Sieczkarek)  

Incorporation by Reference 

 Form 
8-K 

 File Number 
001-33678 

Exhibit/ 
Form 8-K Item  
Reference 
10.5 

Filed 
Herewith 

 Filing Date 
1/06/2016 

8-K 

001-33678 

10.6 

1/06/2016 

10-Q 

001-33678 

10.1 

8/12/2010 

S-1, 
as amended 
S-1, 
as amended 
10-Q 

333-140714 

333-140714 

001-33678 

10.1 

10.2 

10.1 

3/30/2007 

3/30/2007 

8/09/2012 

S-1,  
as amended 

333-140714 

10.3 

5/29/2007 

10-K 
8-K 
10-K 
8-K 
8-K 
8-K 

001-33678 
001-33678 
001-33678 
001-33678 
001-33678 
001-33678 

10.4 
Item 5.02 
10.10 
Item 5.02 
Item 5.02 
10.1 

3/27/2012 
4/24/2013 
3/06/2014 
4/18/2014 
3/24/2015 
11/19/2015     

8-K 

001-33678 

10.1 

1/5/2016 

10.13+  Executive Employment Agreement 

8-K 

001-33678 

10.2 

1/5/2016 

(Employment Agreement of Thomas J. 
Paulson)  

10.14+  Executive Employment Agreement 

8-K 

001-33678 

10.3 

1/5/2016 

(Employment Agreement of Justin M. Hall)  

10.15  Office Lease between Emery Station 

10.16 

10.17 

10.18 

Associates II, LLC (Landlord) and NovaCal 
Pharmaceuticals, Inc. (Tenant), Emerystation 
North  
Fifth Amendment to Lease between Emery 
Station Office II, LLC (Landlord) and 
NovaCal Pharmaceuticals, Inc. (Tenant), 
Emerystation North Project  
Sixth Amendment to Lease between Emery 
Station Office II, LLC (Landlord) and 
NovaCal Pharmaceuticals, Inc. (Tenant), 
Emerystation North Project  
Seventh Amendment to Lease between 
Emery Station Office II, LLC (Landlord) and 
NovaCal Pharmaceuticals, Inc. (Tenant), 
Emerystation North Project  

10.19  Eighth Amendment to Lease between Emery 
Station Office II, LLC (Landlord) and 
NovaCal Pharmaceuticals, Inc. (Tenant), 
Emerystation North Project 

S-1, 
as amended 

333-140714 

10.10 

3/30/2007 

10-K 

001-33678 

10.20 

3/14/2008 

10-Q, 
as amended 

001-33678 

10.1 

11/14/2008     

10-Q 

001-33678 

10.2 

8/09/2012 

X 

63 

 
 
 
 
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
 
 
 
Exhibit 
Number 

  Exhibit Description 

10.20  Master Security Agreement (between the 

Company and General Electric Capital 
Corporation)  

10.21†  Collaboration and License Agreement by and 
between NovaBay Pharmaceuticals, Inc. and 
Galderma S.A.  

 Form 
S-1, 
as amended 

10-Q, 
as amended 

Incorporation by Reference 

 File Number 
333-140714 

Exhibit/ 
Form 8-K Item  
Reference 
10.14 

Filed 
Herewith 

 Filing Date 
5/29/2007 

001-33678 

10.2 

8/04/2009 

10.22†  Amendment No. 1 to the Collaboration and 

10-K 

001-33678 

License Agreement   

10.23†  Amendment No. 2 to the Collaboration and 

10-K 

001-33678 

10.18 

10.24 

10.18 

3/30/2010 

3/10/2011 

3/27/2012 

10-K 

001-33678 

10.24† 

10.25† 

10.26 

10.27 

License Agreement  
International Distribution Agreement (by and 
between the Company and Pioneer Pharma 
Co. Ltd.)  
International Distribution Agreement (by and 
between the Company and Naqu Area 
Pioneer Co. Ltd.)  
First Amendment to International Distribution 
Agreement (by and between the Company 
and Naqu Area Pioneer Co. Ltd.). 
Second Amendment to International 
Distribution Agreement (by and between the 
Company and Naqu Area Pioneer Co. Ltd).  

10.28  Assignment and Assumption Agreement 
(Assignment of International Distribution 
Agreement (Pioneer Pharma) to Naqu Area 
Pioneer Co. Ltd.)  

10-Q 

001-33678 

10.1 

11/01/2012     

10-Q 

001-33678 

10.2 

5/01/2014 

10-Q 

001-33678 

10.3 

5/01/2014 

10-K 

001-33678 

10.28 

3/26/2015 

10.29  Agreement (Amendments to International 

10-K 

001-33678 

10.29 

3/26/2015 

Distribution Agreements by and between the 
Company and Naqu Area Pioneer Co. Ltd.)  

10.30  NovaBay Pharmaceuticals, Inc. Unit Purchase 

10-Q 

001-33678 

10.2 

11/1/2012 

Agreement (by and between the Company 
and Pioneer Pharma (Singapore) Pte. Ltd.)  

10.31  NovaBay Pharmaceuticals, Inc. Warrant 

10-Q 

001-33678 

10.1 

8/01/2013 

Amendment Agreement (by and between the 
Company and Pioneer Pharma (Singapore) 
Pte. Ltd.) 

10.32  NovaBay Pharmaceuticals, Inc. Common 
Stock Purchase Agreement (between the 
Company and Pioneer Pharma (Singapore) 
Pte. Ltd.) 

10.34 

10.33  At-the-Market Offering Agreement (between 
the Company and Ascendiant Capital 
Markets, LLC)  
Securities Purchase Agreement (between the 
Company, Pioneer Pharma (Singapore) Pte. 
Ltd., and Anson Investments Master Fund LP,
et al.) 
Securities Purchase Agreement (between the 
Company, China Kington Investment Co. 
Ltd. and Dr. Dean Rider) 

10.35 

10-K 

001-33678 

10.29 

3/06/2014 

8-K 

001-33678 

1.1 

10/17/2014     

8-K 

001-33678 

10.1 

03/09/2015     

10-Q 

001-33678 

10.1 

8/13/2015 

64 

 
 
 
 
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
 
 
Exhibit 
Number 
10.36 

10.37 

10.38 

10.39 

23.1 
24.1 

31.1 

31.2 

  Exhibit Description 

Stock Purchase Agreement (between the 
Company and the purchasers pursuant to the 
March 3, 2015 Securities Purchase 
Agreement) 
Securities Purchase Agreement (between the 
Company and Jian Ping Fu) 
Securities Purchase Agreement (between the 
Company and Pioneer Pharma (Singapore) 
Pte. Ltd.) 
Securities Purchase Agreement (between the 
Company and Mark M. Sieczkarek) 
Consent of OUM & Co. LLP 
Power of Attorney (contained on signature 
page) 
Certification of the Principal Executive 
Officer of NovaBay Pharmaceuticals, Inc., as 
required by Rule 13a-14(a) or Rule 15d-14(a) 
Certification of the Principal Financial 
Officer of NovaBay Pharmaceuticals, Inc., as 
required by Rule 13a-14(a) or Rule 15d-14(a) 

32.1‡  Certification by the Chief Executive Officer 

of NovaBay Pharmaceuticals, Inc., as 
required by Rule 13a-14(b) or 15d-14(b) and 
Section 1350 of Chapter 63 of Title 18 of the 
United States Code (18 U.S.C. 1350) 
32.2‡  Certification by the Chief Financial Officer of 

NovaBay Pharmaceuticals, Inc., as required 
by Rule 13a-14(b) or 15d-14(b) and Section 
1350 of Chapter 63 of Title 18 of the United 
States Code (18 U.S.C. 1350) 

101.INS  XBRL Instance Document 
101.SCH  XBRL Taxonomy Extension Schema 

Document  

101.CAL  XBRL Taxonomy Extension Calculation 

Linkbase Document 

101.DEF  XBRL Taxonomy Extension Definition 

Linkbase 

101.LAB  XBRL Taxonomy Extension Labels Linkbase 

Document 

101.PRE  XBRL Taxonomy Extension Presentation 

Linkbase Document 

Incorporation by Reference 

 Form 
10-Q 

 File Number 
001-33678 

Exhibit/ 
Form 8-K Item  
Reference 
10.2 

Filed 
Herewith 

 Filing Date 
8/13/2015 

8-K 

8-K 

001-33678 

001-33678 

10.1 

10.2 

2/17/2016 

2/17/2016 

8-K 

001-33678 

10.3 

2/17/2016 

X 
X 

X 

X 

X 

X 

X 
X 

X 

X 

X 

X 

Indicates a management contract or compensatory plan or arrangement 

+ 
†  NovaBay Pharmaceuticals, Inc. has been granted confidential treatment with respect to certain portions of this exhibit (indicated by 

asterisks), which have been separately filed with the Securities and Exchange Commission. 

65