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ProMetic Life Sciences Inc.

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FY2000 Annual Report · ProMetic Life Sciences Inc.
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ProMetic Life Sciences Inc.
Management’s Report

The accompanying consolidated financial statements for ProMetic Life Sciences Inc. are management’s responsibility and have
been  approved  by  the  ProMetic  Life  Sciences  Inc. Board  of  Directors. These  financial  statements  were  prepared  by 
management  in  accordance  with  generally  accepted  Canadian  accounting  principles. They  include  some  amounts  that  are
based on estimates and judgments. The financial information contained elsewhere in the Annual Report is consistent with
that contained in the financial statements.

To ensure the accuracy and objectivity of the information contained in the financial statements, ProMetic Life Sciences Inc.
management maintains a system of internal accounting controls. Management believes that this system gives a reasonable
degree of assurance that the financial documents are reliable and provide an adequate basis for the financial statements, and
that the Company’s assets are properly accounted for and safeguarded.

The Board of Directors upholds its responsibility for the financial statements in this annual report primarily through its audit
committee. The audit committee is made up of outside directors who review the Company’s consolidated annual financial
statements as well as management’s analysis and the operating results, and recommend their approval by the Board. KPMG
LLP, Chartered Accountants, the external auditors designated by the shareholders, periodically meet with the audit committee
to discuss auditing, the reporting of financial information and other related subjects.

Pierre Laurin
Chairman, President
and Chief Executive Officer 

Montreal, Canada, April 10, 2001 

André Bédard
Vice-President Finance
and Chief Financial Officer

Auditors’ Report to the Shareholders

We have audited the consolidated balance sheets of ProMetic Life Sciences Inc. at December 31, 2000 and 1999 and the
consolidated statements of operations and deficit and cash flows for the years then ended. These financial statements are
the responsibility of the Company’s management. Our responsibility is to express an opinion on these financial statements
based on our audits.

We conducted our audits in accordance with Canadian generally accepted auditing standards. Those standards require that
we  plan  and  perform  an  audit  to  obtain  reasonable  assurance  whether  the  financial  statements  are  free  of  material 
misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial
statements. An audit also includes assessing the accounting principles used and significant estimates made by management,
as well as evaluating the overall financial statement presentation.

In  our  opinion, these  consolidated  financial  statements  present  fairly, in  all  material  respects, the  financial  position  of  the
Company as at December 31, 2000 and 1999 and the results of its operations and its cash flows for the years then ended
in accordance with Canadian generally accepted accounting principles.

KPMG LLP
Chartered Accountants

Montreal, Canada, April 10, 2001

22

       ProMetic » Annual Report  2000

ProMetic Life Sciences Inc.
Consolidated Balance Sheets

December 31, 2000 and 1999

Assets

Current assets:

Cash and cash equivalents
Short-term investments
Accounts receivable (note 3)
Inventories (note 4)
Prepaid expenses

Investment (note 5)

Capital assets (note 6)

Deferred development costs (note 7)

Liabilities and Shareholders' Equity

Current liabilities:

Accounts payable and accrued liabilities
Current portion of long-term debt (note 8)

Long-term debt (note 8)

Shareholders' equity:

Share capital (note 9)
Deficit

Commitments (notes 5, 6 and 10)
Contingencies (notes 11 and 13)

See accompanying notes to consolidated financial statements.

On behalf of the Board:

2000
$

1999
$

2,270,316
2,000,000
524,133
300,594
172,659
5,267,702

2,281,245

781,662

–  

235,888
519,597
155,335
1,692,482

741,900

3,620,386

3,367,994

3,018,104

1,665,433

14,187,437

7,467,809

1,741,756
110,758
1,852,514

2,247,229
196,308
2,443,537

–

1,150,114

64,432,379 
49,659,979
(52,097,456)               (45,785,821)
3,874,158
12,334,923

14,187,437

7,467,809

Pierre Laurin, Director

Claude Lemire, Director

       ProMetic » Annual Report 2000

23

ProMetic Life Sciences Inc.
Consolidated Statements of Operations and Deficit

Years ended December 31, 2000 and 1999

Revenues (1)

Expenses before the undernoted items:

Research and development expenses (note 7)
Depreciation of capital assets
Financial expenses

2000
$

1999
$

2,219,029

2,955,640

2,815,166
3,769,555
561,172
240,776

3,945,565
3,184,155
433,832
74,624

Loss from continuing operations

5,167,640

4,682,536

Loss from the discontinuation of the generic pharmaceutical

segment (note 13)

Net loss

Deficit, beginning of year

Share issue expenses

Deficit, end of year

Loss per share from continuing operations

Net loss per share

Weighted average number of outstanding shares

(in thousands)

(1) Revenues include interest income of $139,690 (1999: $69,450).

See accompanying notes to consolidated financial statements.

–  

23,591,290

5,167,640

28,273,826

45,785,821

16,300,223

1,143,995

1,211,772

52,097,456

45,785,821

0.10

0.10

0.11

0.66

53,068

42,889

24

       ProMetic » Annual Report  2000

ProMetic Life Sciences Inc.
Consolidated Statements of Cash Flows

Years ended December 31, 2000 and 1999

Cash flows from operating activities:

Net loss
Adjustments to reconcile net loss to cash flows used by

operating activities:

Loss (gain) on disposal of capital assets
Depreciation of capital assets
Amortization and write-off of deferred development

costs (note 7)

Loss from the discontinuation of the generic

pharmaceutical segment
Cash flows used in operating activities

Net change in non-cash operating working capital items (note 16)

Cash flows from financing activities:

Proceeds from share issues and subscription
Share issue expenses
Increase in long-term debt
Repayment of long-term debt
Decrease in bank overdraft

Cash flows from investing activities:

Acquisition of short-term investments
Acquisition of an investment (note 5)
Additions to capital assets
Proceeds from disposal of capital assets
Deferred development costs (note 7)

2000
$

1999
$

(5,167,640)

(28,273,826)

3,739
561,172

21,613

–  
(4,581,116)

(592,039)
(5,173,155)

14,272,400
(1,143,995)
–  
(735,664)
–  

12,392,741

(2,000,000)
(1,539,345)
(844,909)
27,606
(1,374,284)
(5,730,932)

(20,511)
433,832

735,760

23,591,290
(3,533,455)

1,114,859
(2,418,596)

13,448,750
(1,211,772)
139,911
(115,017)
(168,878)
12,092,994

–  
(741,900)
(572,497)
121,635
(1,551,206)
(2,743,968)

Cash used by the discontinued generic pharmaceutical segment

–  

(10,684,145)

Increase (decrease) in cash and cash equivalents

1,488,654

(3,753,715)

Cash and cash equivalents, beginning of year

781,662

4,535,377

Cash and cash equivalents, end of year

2,270,316

781,662

Other information related to cash flows:
Interests paid during the year
Interests received during the year

Non-cash transaction:

Conversion of long-term debt into shares

See accompanying notes to consolidated financial statements.

229,612
74,947

500,000

55,279
69,540

–  

       ProMetic » Annual Report 2000

25

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements 

Years ended December 31, 2000 and 1999

ProMetic is a leading biopharmaceutical company engaged in the research, development, manufacturing and commercialization
of  a  variety  of  commercial  applications  from  its  platform  technology. ProMetic  owns  proprietary  enabling  technology 
essential for use in large-scale drug purification proteomics, medical applications and therapeutics.

1. Significant accounting policies:

(a) Basis of presentation:

These  consolidated  financial  statements  have  been  prepared  using  accounting  principles  applicable  to  a  going 
concern, which  assume  that  the  Company  will  continue  its  operations  in  the  foreseeable  future  and  be  able  to 
realize assets and satisfy liabilities in the normal course of business.

However, an emerging company assumes that it can expect future profitability and the support of its shareholders 
and other external funding sources, if applicable. Management is of the opinion that adequate resources will be 
available to complete the projects under development as at December 31, 2000.

(b) Consolidation basis:

The consolidated financial statements include the accounts of ProMetic Life Sciences Inc. and its subsidiaries.

(c) Cash and cash equivalents and short-term investments:

Cash equivalents are highly liquid investments purchased with an original maturity of less than three months. Short-
term investments are investment grade short-term debt instruments with original maturities greater than three 
months. Short-term investments are valued at the lower of cost and market value. The carrying value of these 
investments approximates their fair value due to their short maturity.

(d)

Inventories:

Work in process and finished goods are valued at the lower of cost and net realizable value and raw materials are 
valued at the lower of cost and replacement cost. Cost is established using the first in, first out method.

26

       ProMetic » Annual Report  2000

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 2

Years ended December 31, 2000 and 1999

1. Significant accounting policies (continued):

(e)

Investment:

The investment is recorded at cost.

(f) Capital assets:

Capital assets are recorded at cost. Depreciation is provided over the estimated useful lives of capital assets using 
the following methods and rates:

Asset

Leasehold improvements
Equipment and tools
Office equipment and furniture
Computer equipment
Intellectual property

Method

Rate/period

Straight-line
Declining balance
Declining balance
Declining balance
Straight-line

Lease period
10% to 30%
20%
30%
5 to 15 years

Intellectual  property  includes  vested  rights  as  well  as  fees  and  expenditures  incurred  to  obtain  licenses  for 
product manufacturing and marketing.

(g) Deferred development costs:

Development costs of new products and processes, which are considered technically and financially feasible, are 
stated at cost less related research and development tax credits and grants. These costs are amortized from the 
start-up  date  of  commercial  production, based  on  sales. Should  the  Company  determine  that  the  unamortized
balance is in excess of recoverable amounts, the excess will be charged to operations for the year.

(h) Revenue recognition:

The  Company  recognizes  revenues  from  various  research  and  technology  agreements  when  the  contracted 
services are provided and the various conditions, if any, are met.

(i)

Scientific research and experimental development expenses:

Research and development expenditures are charged to operations in the year in which they are incurred, net of 
related tax credits.

       ProMetic » Annual Report 2000

27

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 3

Years ended December 31, 2000 and 1999

1. Significant accounting policies (continued):

(j)

Foreign currency translation:

Foreign currency transactions are translated into Canadian dollars using the temporal method. Under this method,
monetary assets and liabilities are translated at year-end exchange rates while non-monetary items are translated 
at  historical  exchange  rates. Expense  items  are  translated  at  the  exchange  rate  on  the  transaction  date  or  at 
average  exchange  rates  prevailing  during  the  period. Exchange  gains  or  losses  are  included  in  the  statement 
of operations.

(k)

Income taxes:

The Company uses the asset and liability method of accounting for income taxes. Future income tax assets and 
income  tax  liabilities  are  recognized  in  the  balance  sheet  to  account  for  the  future  tax  consequences  of  timing 
differences between the respective accounting and taxable value of balance sheet assets and liabilities. As appropriate,
a valuation allowance is recognized to decrease the value of tax assets to an amount that is more likely than not to
be realized. Future income tax assets and income tax liabilities are measured using the income tax rates that are 
expected to apply when the asset is realized or the liability is settled. The effect of changes in income tax rates is 
recognized in the year during which these rates change.

(l)

Stock option plan:

The Company has established a stock option plan, as described in note 9 (b). No charge is recognized for this 
plan  when  stock  options  are  granted. Any  consideration  paid  on  the  exercise  of  stock  options  is  credited  to   
share capital.

(m) Use of estimates:

The  preparation  of  financial  statements  in  conformity  with  generally  accepted  accounting  principles  requires 
management  to  make  estimates  and  assumptions  that  affect  the  reported  amounts  of  assets  and  liabilities  and 
disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of 
revenues and expenses during the reporting period. Significant items for which management must make estimates 
related to the valuation and assessment of recoverability of intellectual property and deferred development costs.
Reported amounts and note disclosure reflect the overall economic conditions that are most likely to occur and 
anticipated measures to be taken by management. Actual results could differ from those estimates.

28

       ProMetic » Annual Report  2000

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 4

Years ended December 31, 2000 and 1999

2. Change in accounting policy:

Effective  January  1, 2000, the  Company  adopted  Section  3465  of  the  CICA  Handbook, Income  taxes. Section  3465 
requires  a  change  from  the  deferred  method  of  accounting  for  income  taxes  to  the  asset  and  liability  method  of 
accounting for income taxes.

The  cumulative  effect  of  this  change  in  accounting  for  income  taxes  is  nil  as  of  January  1, 2000  as  the  Company 
recorded a valuation allowance equal to the future income tax asset that could have been recorded if it would have 
been more likely than not that a portion or all of this future income tax asset would realize.

3. Accounts receivable:

Trade
Sales taxes receivable
Interest receivable
Other

4.

Inventories:

Raw materials
Work in progress and finished goods

5.

Investment:

2000
$

344,496
60,244
64,742
54,651

524,133

2000
$

148,552
152,042

300,594

1999
$

64,668
158,721

–  

12,499

235,888

1999
$

321,710
197,887

519,597

As  of April  13, 2000, through AlphaOne-ProMetic  Inc. (“AlphaOne-ProMetic”), the  Company  entered  into  a  50-50 
joint  venture  with  Arriva  Pharmaceuticals, Inc. (“Arriva”; formerly  known  as  AlphaOne  Pharmaceuticals, Inc.)  of 
Alameda, California  for  the  development  of  applications  relating  to  commercializing  serine  protease  inhibitors  as  a 
platform  for  various  pharmaceutical  products  for  dermatological  (ex.: eczema, psoriasis, genital  herpes),
gastrointestinal  (ex.: Crohn’s  disease,
irritable  bowel  syndrome)  and  urinary  tract  indications. The  first  serine 
protease pursued is rAAT, a lead compound produced in genetically-engineered yeast cells.

       ProMetic » Annual Report 2000

29

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 5

Years ended December 31, 2000 and 1999

5.

Investment (continued):

Arriva  has  granted  to  AlphaOne-ProMetic  an  exclusive, perpetual  license  to  develop, manufacture  and 
commercialize  these  serine  protease  inhibitors  and  the  Company  has  granted  AlphaOne-ProMetic  an  exclusive,
perpetual  license  for  the  use  of  its  Mimetic  LigandTM purification  technology  for  the  indications  within  the  scope 
of the joint venture. The Company has undertaken to fund the joint venture for $4 million US beginning April 1st, 2001,
on the basis of monthly instalments of $100,000 US each beginning April 1st, 2001, and up to the approval of next year 
joint  venture  budget  in  December  2001. The  Company  had  also  undertaken  to  purchase  preferred  voting  shares  in 
Arriva for a total amount of $1.5 million US representing a total equity position of 5.6%.This transaction was completed 
in November 2000.

No expenses relating to the project activities had been allocated to the joint venture as of December 31, 2000.

6. Capital assets:

Leasehold improvements
Equipment and tools
Office equipment and furniture
Computer equipment
Intellectual property ((a) and (b))

Leasehold improvements
Equipment and tools
Office equipment and furniture
Computer equipment
Intellectual property ((a) and (b))

30

       ProMetic » Annual Report  2000

Cost
$

390,856
2,412,439
157,716
176,654
2,471,003

Accumulated
depreciation
$

136,824
1,472,353
34,540
57,231
287,334

2000

Net book
value
$

254,032
940,086
123,176
119,423
2,183,669

5,608,668

1,988,282

3,620,386

Cost
$

127,241
1,091,468
56,396
94,486
2,414,972

3,784,563

Accumulated
depreciation
$

15,306
215,926
14,876
35,053
135,408

416,569

1999

Net book
value
$

111,935
875,542
41,520
59,433
2,279,564

3,367,994

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 6

Years ended December 31, 2000 and 1999

6. Capital assets (continued):

(a) The Company owns the rights, title and interest in and to the know-how, the information, the technology and the 
patents  relating  to  its  Mimetic  Ligand Technology. Part  of  these  rights, title  and  interest  were  assigned  to  the 
Company by the Cambridge University’s Institute of Biotechnology in consideration of the payment of continuing 
royalties; the others have been developed by the Company.

(b) Pursuant to a license agreement dated November 9, 1995, and amended as of December 20, 2000 with DCV, Inc.,
the  Company  owns  the  exclusive  right  to  use  under  the  patent  rights, a  technology  permitting  the  link  of 
its Mimetic Ligands™ to a matrix with a Teflon-like surface such as the Teflon beads (registered mark of Dupont 
Chemical  &  Energy  Operations,
Inc.)  and  the  Company’s  Perfluorocarbon  beads  (Perfluorosorb™). This 
technology  is  useful  in  chromatographic  applications  and  for  medical  devices. This  license  is  subject  to  the 
payment  of  a  royalty  to  DCV, Inc. on  net  sales  with  respect  to  any  products  covered  by  the  patent  rights.

7. Deferred development costs:

Research and development

Incurred during the year

Less: Amount deferred

Amortization of deferred development costs

Write-off of deferred development costs

2000
$

1999
$

5,122,226

3,999,601

1,374,284
3,747,942

6,000

15,613

1,551,206
2,448,395

66,039

669,721

Expense for the year

3,769,555

3,184,155

Deferred development costs

Deferred development costs, beginning of year

1,665,433

2,430,271

Deferred development costs for the year
Amortization of deferred development costs
Write-off for the year
Portion related to the discontinued 
generic pharmaceutical segment

1,374,284
(6,000)
(15,613)

1,551,206
(66,039)
(669,721)

–  

(1,580,284)

Deferred development costs, end of year

3,018,104

1,665,433

       ProMetic » Annual Report 2000

31

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 7

Years ended December 31, 2000 and 1999

8. Long-term debt:

Bank loan, bearing interest at prime rate plus 2.5%, payable 
by monthly capital and interest installments of $9,328,
maturing in December 2001

Due to shareholders, bearing interest at prime rate plus 3.5% 
from January 2000, of which $500,000 were converted into 
subordinate voting shares and $535,000 were repaid in 2000

Due to a shareholder, unsecured, bearing interest at prime 

rate plus 2.25%, payable on demand

Current portion of long-term debt

9. Share capital:

Authorized and without par value:

2000
$

1999
$

110,758

206,511

–  

–  

110,758

110,758

1,035,000

104,911
1,346,422

196,308

–

1,150,114

Unlimited number of Subordinate voting shares, participating, carrying one vote per share

20,000,000  Multiple  voting  shares, participating, carrying  ten  votes  per  share, convertible  at  the  option  of  the 
holder  or  automatically  converted  upon  their  sale  to  a  third  party  by  the  holder  into  an  equal  number 
of Subordinate voting shares

An unlimited number of Preferred shares, no par value, issuable in one or several series:

1,050,000  Preferred  shares, series  A, non-participating, non-voting, convertible  at  the  option  of  the  holder 
into  subordinate  voting  shares  at  $0.50  per  share  except  for  unpaid  dividends, convertible  at  a  rate  equal 
to  the  trading  average  of  the  subordinate  voting  shares  during  the  20  days  preceding  the  conversion,
preferential cumulative dividend of 12% per year, payable quarterly

32

       ProMetic » Annual Report  2000

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 8

Years ended December 31, 2000 and 1999

9. Share capital (continued):

Authorized and without par value (continued):

An unlimited number of Preferred shares, no par value, issuable in one or several series (continued):

950,000  Preferred  shares, series  B, non-participating, non-voting, convertible  at  the  option  of  the  holder  into 
subordinate  voting  shares  at  $0.60  per  share  except  for  unpaid  dividends, convertible  at  a  rate  equal  to  the 
trading  average  of  the  subordinate  voting  shares  during  the  20  days  preceding  the  conversion, preferential 
cumulative dividend of 12% per year, payable quarterly

Issued and fully paid:

46,254,045 Subordinate voting shares (1999 - 32,777,747)
13,703,197 Multiple voting shares (1999 - 14,303,057)
1,050,000 Preferred shares, series A (1999-nil)
950,000 Preferred shares, series B (1999-nil)
1,957,504 warrants (ii and iii) (1999 - nil)

Subscriptions

2000
$

60,787,994
1,644,385
1,050,000
950,000

–  
–  

1999
$

46,395,130
1,714,849

–  
–  
–  

1,550,000

64,432,379

49,659,979

Cumulative dividends in arrears on preferred shares amount to $208,525 as at December 31, 2000 (1999 - nil).

(a) Share issuance:

(i) On  February  18, 2000, the  Company  issued  2,000,000  preferred  shares  (1,050,000  Series A  and  950,000 

Series B) at a price of $1 per share, for gross proceeds of $2,000,000.

(ii) On  March  16, 2000, the  Company  issued  3,629,295  units  for  a  gross  proceeds  of  $3,084,900. Each  unit  is 
comprised  of  one  Subordinate  voting  share  and  one-half  of  a  warrant. Each  whole  warrant  entitles  the
holder  thereof  to  purchase  one  Subordinate  voting  share  at  any  time  between  the  date  of  issuance  and  a 
period of 12 months thereafter, at a price of $1.10 per share.

(iii) On May 15, 2000, the Company issued 357,143 units for a gross proceeds of $500,000. Each unit is comprised 
of  one  Subordinate  voting  share  and  0.4  of  a  warrant. Each  whole  warrant  entitles  the  holder  thereof  to 
purchase one Subordinate voting share at any time between the date of issuance and a period of 12 months 
thereafter, at a price of $1.40 per share.

       ProMetic » Annual Report 2000

33

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 9

Years ended December 31, 2000 and 1999

9. Share capital (continued):

(a) Share issuance (continued):

(iv) On September 6, 2000, the Company proceeded with a public issue of 6,600,000 Subordinate voting shares at 

a price of $1.25 per share, for gross proceeds of $8,250,000.

(v) On November 3, 2000, the Company proceeded with a public issue of 990,000 Subordinate voting shares at 
a price of $1.25 per share, for gross proceeds of $1,237,500 representing the exercise in whole of the 15% 
option to cover allotments granted in the September 6, 2000 public issue.

(vi) During  the  year  2000, 1,300,000  Subordinate  voting  shares  were  issued  following  the  conversion  of 

shareholders’ advances.

(vii) During the year 2000, 599,860 Multiple voting shares were converted into 599,860 Subordinate voting shares.

(viii) As  set  forth  in  a  prospectus  dated August  12, 1999, 6,799,286  Subordinate  voting  shares  have  been  issued 
following the exercise of the 6,799,286 special warrants by their holders. These special warrants were issued,
on June 25, 1999, for net proceeds of $11,125,332, net of agents’ fees and estimated issuance expenses.

(ix) During  the  year  1999, 1,145,806  Multiple  voting  shares  were  converted  into  1,145,806  Subordinate 

voting shares.

(b) Stock options:

The Company established a stock option plan for its directors, officers and employees or consultants. The plan 
provides  that  the  aggregate  number  of  shares  reserved  for  issuance  at  any  time  under  the  plan  and  any  other 
employee incentive plans may not exceed 3,500,000 Subordinate voting shares. The options could be exercised in 
a period not exceeding 10 years from the date they were granted.

Year of grant

1997
1998
1999
2000

Subscription price 
(in dollars)

Number of options outstanding
1999

2000

$1.49 to $1.75
$2.00 to $3.00
$1.00 to $2.00
$1.35

165,502
65,500
2,265,000
300,000

210,318
118,000
2,727,000

–  

2,796,002

3,055,318

34

       ProMetic » Annual Report  2000

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 10

Years ended December 31, 2000 and 1999

9. Share capital (continued):

(b) Stock options (continued):

Changes in the number of options outstanding during the past two fiscal years were as follows:

Number of options as at December 31, 1998
Granted
Cancelled

Number of options as at December 31, 1999

Granted
Cancelled

Number of options as at December 31, 2000

The following table summarizes information about stock options outstanding at December 31, 2000:

Range of
exercise prices

Number
outstanding

$1.00 to $1.49
$1.50 to $1.75
$2.00 to $3.00

2,327,002
148,000
321,000

2,796,002

Weighted
average
remaining
contractual
life (in years)

9.03
6.67
7.98

Weighted
average
exercise
price
$

1.05
1.58
2.16

Number
exercisable

1,072,401
88,800
77,300

1,238,501

Options

756,911
2,925,750
(627,343)

3,055,318

300,000
(559,316)

2,796,002

Weighted
average
exercise
price
$

1.00
1.58
2.26

       ProMetic » Annual Report 2000

35

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 11

Years ended December 31, 2000 and 1999

10. Commitments:

The  Company  has  commitments  under  various  operating  leases  for  office  space  and  laboratories. The  minimum 
annual payments are as follows:

2001
2002
2003
2004
2005
2006 and thereafter

11. Contingency:

$

678,602
669,728
592,292
558,178
632,438
2,835,511

The Company and a subsidiary, ProMetic BioSciences Inc., have an outstanding claim from a former employee for an 
approximate amount of $320,000. This claim was rejected by the Superior Court (Quebec, Canada) on August 8, 2000 
and the former employee appealed against this judgment. After obtaining representation from their legal counselors,
management  is  of  the  opinion  that  this  claim  is  without  substantial  merit  and  no  provision  was  recorded  in  these 
consolidated financial statements in that respect. Settlements, if any, will be charged to operations in the period in which 
the settlement occurs.

12. Financial instruments:

(a) Fair values:

The carrying amount of cash and cash equivalents, short-term investments, accounts receivable, accounts payable 
and accrued liabilities approximates the fair value because of the near-term maturity of these instruments. The 
carrying  amount  of  the  Company’s  floating  rate  long-term  debt  approximates  its  fair  value  because  it  bears 
interest at current market floating rates.

(b) Credit risk:

The Company reviews a new customer’s credit history before extending credit and conducts regular reviews of its 
existing customers’ credit performance.

(c) Foreign currency rate risk:

The Company receives a substantial part of its revenues in US dollars and the majority of its expenses are incurred 
in Sterling pounds. The Company does not possess nor issue financial instruments for hedging or trading purposes.

36

       ProMetic » Annual Report  2000

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 12

Years ended December 31, 2000 and 1999

13. Discontinuation of the generic pharmaceutical segment:

On  September  30, 1999, the  Company  discontinued  its  activities  in  the  generic  pharmaceuticals  business  when  its 
subsidiary ProMetic Pharma Inc. (“Pharma”) made an assignment in favour of its creditor generally under the Bankruptcy 
and Insolvency Act. As a result, the following legal proceedings took place:

(a) A  garanteed  creditor  of  Pharma,

is  claiming  $2,021,619  from  the  Company  pursuant  to  guarantees  and 
agreements  related  to  certain  credit  contracts  concluded  between  this  creditor  and  Pharma. The  action 
was commenced on June 29, 2000.

(b) A legal action was filed by a creditor of Pharma for recovery of certain amounts. The claim is for $305,104.

The Company is contesting these claims and on the basis of the opinions provided by legal counsels, the Company is of 
the view that it has valid grounds for defence in respect of each claim. While management is confident to avoid any 
unfavorable outcome, it should however be noted that any settlement in favour of one of the above creditors could 
have an adverse effect on the Company’s cash flows, its results of operations and its financial position. No provision 
related to these claims was recorded in these consolidated financial statements.

Settlements, if any, will be charged to operations in the period in which the settlement occurs.

14. Related party transactions:

The Company entered into the following transaction with related parties:

Consulting fees paid to directors

2000
$

1999
$

194,175

288,350

       ProMetic » Annual Report 2000

37

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 13

Years ended December 31, 2000 and 1999

15. Income taxes:

Significant components of the Company’s net future income taxes balances are as follows:

Future income tax assets:

Capital assets
Net losses
Financing costs
Undeducted research and development expenses

Less: valuation allowance

Net future income tax assets

Future income tax liabilities:

Capital assets

Net future income tax assets

$

11,125
5,256,343
1,143,648
265,020
6,676,136
(6,431,222)

244,914

244,914

–  

The Company has unutilized tax loss carryforwards and unamortized share issue expenses for which no tax benefit has 
been reflected in the financial statements. These items may be used to reduce taxable income and income taxes in 
future years. As at December 31, 2000, expiry dates and amounts are as follows:

Tax loss carryforwards expiring in 2002
Tax loss carryforwards expiring in 2003
Tax loss carryforwards expiring in 2004
Tax loss carryforwards expiring in 2005
Tax loss carryforwards expiring in 2006
Tax loss carryforwards expiring in 2007
Tax loss carryforwards expiring in 2010
Tax loss carryforwards expiring in 2011
Tax loss carryforwards expiring in 2012
Tax loss carryforwards expiring in 2018
Tax loss carryforwards expiring in 2019
Tax loss carryforwards expiring in 2020
Tax loss carryforwards, no expiration date
Share issue expenses to be amortized over 1 year
Share issue expenses to be amortized over 2 years
Share issue expenses to be amortized over 3 years
Share issue expenses to be amortized over 4 years

38

       ProMetic » Annual Report  2000

Federal
$

42,580
525,630
764,964
1,100,268
4,091,000
3,213,135

–  
–  
–  
–  
–  
–  
–  

Provincial
$

42,580
364,589

–  

1,149,113
4,091,000
3,213,135

–  
–  
–  
–  
–  
–  
–  

151,499
1,185,481
747,950
915,196

151,499
1,185,481
747,950
915,196

Other
countries
$

–  
–  
–  
–  
–  
–  

162,699
467,255
1,170,475
1,447,184
540,082
77,050
62,329

–  
–  
–  
–  

12,737,703

11,860,543

3,927,074

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 14

Years ended December 31, 2000 and 1999

16. Net change in non-cash operating working capital items:

(Increase) decrease in accounts receivable
Decrease (increase) in inventories
Increase in prepaid expenses
(Decrease) increase in accounts payable and

accrued liabilities

17. Segmented information:

2000
$

(288,245)
219,003
(17,324)

(505,473)

1999
$

1,195,223
(105,656)
(89,149)

114,441

(592,039)

1,114,859

ProMetic  is  a  leading  biopharmaceutical  company  engaged  in  the  research, development, manufacturing  and 
commercialisation  of  a  variety  of  commercial  applications  from  its  platform  technology. ProMetic  owns  proprietary 
enabling technology essential for use in large-scale drug purification proteomics, medical applications and therapeutics.

Revenues by geographic segment are as follows:

United States
United Kingdom
Europe (excluding United Kingdom)
Other
Canada
Intersegment sales

Net losses from the continuing operations by geographic segment are as follows:

Canada
United States
United Kingdom

2000
$

1,256,989
797,025
139,652
37,598
160,672
(172,907)

1999
$

1,469,550
609,247
1,559,158
57,745
74,012
(814,072)

2,219,029

2,955,640

2000
$

3,890,293
777,740
499,607

1999
$

3,021,676
1,003,364
657,496

5,167,640

4,682,536

       ProMetic » Annual Report 2000

39

ProMetic Life Sciences Inc.
Notes to Consolidated Financial Statements, page 15

Years ended December 31, 2000 and 1999

17. Segmented information (continued):

Assets by geographic segment are as follows:

Canada
United Kingdom
United States

Capital assets by geographic segment are as follows:

United Kingdom
Canada
United States

Capital expenditures by geographic segment are as follows:

United Kingdom
Canada
United States

Major customer information:

2000
$

8,010,094
5,543,422
633,921

1999
$

4,489,475
2,377,380
600,954

14,187,437

7,467,809

2000
$

2,599,566
973,143
47,677

1999
$

2,311,675
971,888
84,431

3,620,386

3,367,994

2000
$
660,163
181,059
3,687

844,909

1999
$
152,710
416,216
3,571

572,497

As  the  Company  is  in  its  development  phase, a  considerable  percentage  of  its  R&D  revenues  are  derived  from 
a relatively small number of customers.

18. Comparative figures:

Comparative figures have been reclassified in order to conform with the current year’s presentation.

40

       ProMetic » Annual Report  2000