Quarterlytics / Healthcare / Medical - Diagnostics & Research / Psychemedics Corp.

Psychemedics Corp.

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Employees 201-500
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FY2010 Annual Report · Psychemedics Corp.
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CORPORATE PROFILE

Psychemedics Corporation
The Companys multi patented

is the worlds largest

provider

of hair testing

for the detection of drugs of abuse

process

has been utilized

by thousands

of clients

including

over 10% of

the

Fortune

500 companies

for pre-employment and random drug

testing Major police departments Federal

Reserve Banks schools

and other public

entities

also secure

the safety and reliability of

their activities

from

drug abusers
internet ECommerce website wwwdrugfreeteenagers.com

by using our unique

process Our personal drug

testing

service PDT-90 is available via our

The Companys drug

test provides for the

detection of cocaine marijuana opiates including
and PCP We strongly believe our drug

oxycontin

and vicodin

amphetamines

including

Ecstasy

testing method to be superior

to any other product

currently in use

including

traditional

urine testing

and other hair testing methods

LYNCH BREWER
HOFFMAN FINKLLP
.i-ittorneys at Law

________________________________________________

75 FEDERAL

STREET

7TH FLOOR

BOSTON

MASSACHuSETrS

02110

TEL 617 951-0800 FAX 617 951-0811
WWW.LYNCHBREWER.COM

OWEN
LYNCH
EDWARDS BREWER JR
HOFFMAN
ALAN

DALE

KERESTER

JENNIFER

PLAIT

WHITMANt

CHRISTINE
THOMAS
SONIAJ EWONt

CLEMENS

JR

LISA

CASEY

ALSO ADMI1TED
ADMITTED

ALSO

tALSO ADMITTED

IN CT

IN FL

IN ME

ALSO

ADMI1TED

IN NH

PETERW FINKt
JOHN

DENNISt

PATRICKJ
ANNE HOFFMAN

KINNEY

April

201

OVERNIGHT DELIVERY

Securities and Exchange Commission

Street NE
100
Washington DC 20549

Re

Corporation

Psychemedics
Commission File No 1-13738
CIK No 0000806517

Dear Sir/Madam

Pursuant

to Rule 4a-3 of the Securities Exchange Act of 1934 on behalf of

Psychemedics

as supplemental
Corporation
Corporations 2010 Annual Report Except for the Companys Form 10-K

am enclosing

information seven

copies of

Psychemedics
included therein which was filed with the Commission on March 25 2011 pursuant
to be considered

to be treated as soliciting material

and is not

this report

is not

to Rule 13a-

to be filed

under the Securities Exchange Act of 1934

Please acknowledge

receipt of
copy of this cover letter and returning it

the foregoing materials by date stamping the enclosed
to the undersigned in the self-addressed

metered

envelope provided

enclosures

cc

Nell Lemer

Psychemedics Corporation
via email without end

Nicole Cunneen

BDO USA LLP

with

copy of end regular U.S Mail

312843.1

Dear Fellow Shareholders

In 2010 sales and profits were back on the growth track Revenues advanced

19% and

our EPS increased 72% over last year While we are very proud of
been profitable every year since 1993 including the severe 2009 recession
continues

that we have
focus
to be sales and earnings growth While some of our growth in 2010 can be

the fact

our

attributed to the economic

recovery the primary increase has come from new customers and

introducing new programs to existing customers

As

reported

to you last year in 2009 we made major investments

in sales and

marketing at
salary cuts In 2010 while we continued

the same time we had to make major reductions

tight cost controls we again made major

including across-the-board

investments

in sales and marketing to grow our business

In April we brought on Jim Dyke to be our Corporate Vice President of Sales

This is

Marketing
and general manager experience He is charged with accelerating
given his extremely

new position for us Jim has extensive professional

he is focused

strong background

on profitable

our sales growth and

sales growth

sales experience

In July we announced
the UK an international

of

that we had signed
science-based

and diagnostic services and reference standards

company and market
to market

sales and marketing agreement with LGC
forensic

leader

in analytical

the patented Psychemedics

hair

analysis drug test
whose forensic science capabilities

to the UK We are very proud to be working with LGC company
sets the highest quality standards

in the UK Since we

the highest quality and most cost effective
provide
match With this agreement we hope to capitalize
in the UK and Europe and help companies
place

drug test available this is
on the developing

perfect

growth opportunities
drug free work

there establish and maintain

We also continued

to add to our

internal

sales

team and undertook and completed

of our website www.Psychemedics.com

total overhaul
well as to expand our e-commerce platform We strongly believe
in sales and marketing position us well
investments

for future growth

to improve our internet presence as

that

these continued

In addition Neil Lerner joined us as our new Vice President and Controller Neils

background with

extensive
added strength He has come in and restructured the finance department
in the Company with the key data required to drive our business as well as handle our
external

number of major large as well as small companies

to better

gives us

serve all

reporting

In September

2010 for the fourth year

in

row DeMarche Associates Inc

leading

research and financial

consulting firm included

investment
companies with the Best CEOs in the nation This is awarded
American firms with CEOs who had generated the most shareholder
compensation over
effort at Psychemedics We are all pleased with this award as we strive to accomplish our
goal of generating maximum return for shareholders while delivering the highest quality
most cost effective

three years We mention this because it is truly

small group of
value

the previous

per unit of CEO

in their listing of

Psychemedics

team

to

drug test available

With our strong track record of profitability

and the major investments

in sales and

marketing that we have made over
future growth and come into 2011 with great confidence
largest provider of drug testing using hair analysis We have the most sensitive
available which results

rate This higher detection

higher detection

in

the last two years we believe we are well positioned for

in our future We are the worlds

rate serves as

drug test

powerful upfront deterrent
is

our proprietary process allows

to drug use What makes our

test

the most sensitive

and effective

us to get virtually

100% of the drug out of

the hair

if

you cant get
test in this case radioimmunoassay

the drug out you cant measure it

and all our

we have the most sensitive
tests are cleared by the FDA

screening
we have

been and continue
have the most extensive

legal

track record

supporting

to be the leader

in mass-spectrometry confirmation testing

we
our proprietary testing method We
industries including over 10% of the

and

wide base of
have thousands
Fortune 500 along with schools and major law enforcement agencies We believe we have

of customers across

very

strong technology

platform and customer base to build on and are excited

about

the

years ahead

In addition the Companys balance
million in cash and short-term investments

our confidence

the financial

success of

in the future and remain committed to rewarding shareholders

and no long term debt Our directors share
and sharing
the company with them as they grow We are very pleased now to

sheet remains strong with approximately $5.7

have had 58 consecutive

quarters of paying

dividend

would like to thank all our clients

deterring drug abuse our directors

for the major contribution they are making
for their counsel and guidance and all my teammates

in

at

for their continued

commitment and dedication

to excellence

in serving our

want

to thank you our shareholders

for your continued

support

Psychemedics
customers And

Sincerely

Raymond

Kubacki

Chairman President

and

Chief Executive Officer

SECURITIES

AND EXCHANGE COMMISSION

UNITED STATES

Washington D.C 20549

FORM 10-K

ANNUAL REPORT PURSUANT TO SECTION 13 OR
OF THE SECURITIES

EXCHANGE ACT OF 1934

For the Fiscal Year Ended December 31 2010

TRANSITION REPORT PURSUANT
OF THE SECURITIES

EXCHANGE ACT OF 1934

TO SECTION 13 OR 15d

Commission File Number 1-13738

PSYCHEMEDICS CORPORATION

Exact Name of Registrant

as Specified

in Its Charter

Delaware

State or Other

Jurisdiction

of

Incorporation

or Organization

125 Nagog Park
Acton Massachusetts

Address of Principal Executive Offices

58-1701987

I.R.S Employer
No

Identification

01720

Zip Code

Registrants Telephone Number Including Area Code 978 206-8220

Securities registered pursuant

to Section 12b of

the Act

Common Stock

$0.005 par value

Title of Class

Securities registered pursuant

to Section 12g of the Act None

Indicate

by

1934 YesE No

check mark if the

registrant

is

well-known

seasoned

issuer as defined in Rule 405 of the Securities

Exchange Act of

Indicate

by

check mark if the

registrant

is not required to file reports pursuant

to Section

13 or Section 15d of the Securities

Exchange Act of 1934

Yes

No

Indicate

by check mark whether

the

registrant

has filed all

reports

required to be filed by Section

13 or 15d of the Securities

Exchange Act of 1934 during the preceding

12 months or for such

shorter period that

the registrant was required to file such

reports

and

has been

subject

to such

filing requirements for the past

90 days

Yes

No

Indicate

by check mark whether

the

registrant

has submitted electronically

and posted on its corporate web site if any every

Interactive

Data File required to be submitted and posted pursuant

to Rule 405 of Regulation

S-T during the preceding

12 months or for

such

shorter period that

the

registrant was required to submit and post such

files Yes

No

Indicate

by check mark if disclosure

of delinquent

filers

pursuant

to Item 405 of Regulation

S-K 229.405 of this chapter

is not

contained herein and will not be contained

to the best of registrants

knowledge in definitive

proxy or

information

statements

incorporated

by reference in Part

III of this Form 10-K or any amendment

to this Form 10-K

Indicate

by check mark whether

the registrant

is

large

accelerated

filer an accelerated

filer or

non-accelerated

filer See definition

of accelerated

filer and

large accelerated

filer in Rule 12b-2 of the Securities

Exchange Act of 1934

Large Accelerated
Do not check

if

Filer

Accelerated

Filer

Non-Accelerated

Filer

Smaller Reporting

Company

smaller reporting

company

Indicate

by

check mark whether

the registrant

is

shell company

as defined in Rule 12b-2 of

the Securities

and Exchange

Act of 1934

Yes

No

As of June 30 2010

there were 5212835 shares

of Conmion Stock of the Registrant outstanding The aggregate market

value of the

Common Stock of the Registrant held by non-affiliates
and 5% shareholders are affiliates of the Registrant

price

of $7.98 per share

on June 30 2010

assuming for these

purposes

but not conceding

that all executive

officers

directors

as of June 30 2010 was approximately

$18 million computed based

upon the closing

As of March 22 2011

there were

of Common Stock of the Registrant outstanding

shares

5212013
DOCUMENTS INCORPORATED

BY REFERENCE

Part

III of this Annual Report

on Form 10-K incorporates by reference portions

of the Registrants

definitive

proxy statement

to be

filed with the Securities

and Exchange Commission no later than 120 days after

the close of its fiscal year provided

that

if such

proxy

statement

is not filed with the Commission in such

120-day period an amendment

to this Form 10-K shall be filed no later than the end of

the 120-day period

SPECIAL NOTE REGARDiNG FORWARD-LOOKING STATEMENTS

Some of the statements
Registrants Common Stock

under Business Risk Factors Legal Proceedings Market
and Related

Matters and Management Discussion

Stockholder

for

and Analysis of

Financial Condition
Form 10-K constitute forward-looking
amended and Section

and Results of Operations and elsewhere

in this Annual Report

on Form 10-K this

statements

under Section

27A of

the Securities Act of 1933

as

21E of the Securities Exchange Act of 1934

as amended

including

statements made

with respect

to future earnings per share

future revenues

future operating income future cash

flows

competitive

and strategic

initiatives

potential

stock

repurchases

and future liquidity

needs These statements

involve known and unknown

risks uncertainties

and other factors

that may cause

results levels

of activity

growth performance

earnings per share or achievements

to be materially different

from any future results

levels of activity growth performance

earnings per

share or achievements

expressed

or implied by such

forward-looking

statements

The forward-looking

statements

included in this Form 10-K and referred to elsewhere

are related to

future events or our strategies

or future financial

forward-looking

statements

by terminology

such

performance
as may should believe anticipate

In some cases you can

identify

future

potential
plan expand focus through strategy provide offer allow commitment

opportunity

growth leader could expect

estimate encourage

intend

implement result
include or the negative

increase establish perform make continue
terms or comparable terminology All

of such

can ongoing

forward-looking

statements

included

in this Form 10-K are based

on information

available to us as of

the filing date of this report

and the

Company assumes no obligation

to update any such

forward-looking

statements

Our actual

results

could

differ materially from the forward-looking

statements

Important

factors

that

could

cause

actual

results

to differ

materially from expectations

reflected

in our forward-looking

statements

include those described

in Item 1A

Risk Factors

PSYCHEMEDICS CORPORATION

FORM 10-K
ANNUAL REPORT
For the Year Ended December 31 2010

TABLE OF CONTENTS

Item

Business

Item 1A

Item lB

Risk Factors

Unresolved

Staff Comments

Properties

Legal

Proceedings

Reserved

PART

PART II

Item

Item

Item

Item

Item

Item

Item 7A

Item

Item

Market

for Registrants Common Equity Related

Stockholder

Matters and Issuer

Purchases

of Equity Securities

Selected Financial Data

Managements Discussion

and Analysis of Financial Condition

and Results of

Operations

Quantitative

and Qualitative Disclosures About Market Risk

Financial Statements

and Supplementary Data

in and Disagreements

With Accountants

on Accounting

and Financial

Changes

Disclosure

Item 9A.T Controls

and Procedures

Item 9B

Other

Information

Item 10

Directors

Executive

Officers and Corporate Governance

Item 11

Executive

Compensation

PART III

Item 12

Security Ownership of Certain Beneficial Owners

and Management

and Related

Stockholder

Matters

Item 13

Item 14

Certain Relationships

and Related

Transactions

and Director

Independence

Principal Accounting

Fees

and Services

Item 15

Exhibits

Financial Statement

Schedules

PART IV

OTHER ITEMS

Signatures

Power

of Attorney

11

Page

12

12

12

12

13

15

15

21

22

39

39

40

41

42

42

42

42

43

44

44

Available

Information Background

Psychemedics Corporation

the Company or Psychemedics

maintains executive

offices

located at

PART

125 Nagog Park Acton MA 01720 Our
NASDAQ Stock Exchange Market under
The Company makes available

telephone

the symbol PMD Our

number

is 978 206-8220 Our stock

is traded on the

Internet address

is wwwpsychemedics.com

free of charge on the Investor

Information

section of its website its Annual

Report

on Form 10-K Quarterly Reports

on Form 10-Q Current Reports

on Form 8-K and all amendments

to

those reports as

soon

as

reasonably

practicable after

such material

is electronically

filed with the Securities

and Exchange

Commission

the SEC Copies

Corporation Attn Investor Relations
SEC may be viewed or obtained
Internet site at www.sec.gov We do not
Annual Report

on Form 10-K

are also available without

charge from Psychemedics

125 Nagog Park Acton MA 01720 Alternatively reports filed with the

at the SEC Public Reference Room in Washington D.C or the SECs

intend for

information

contained

in our website

to be part of this

Item

Business

General

Psychemedics Corporation

is

Delaware corporation

organized

on September 24 1986 to provide testing

services for the detection of abused

substances

through

the analysis of hair samples The Companys testing

methods utilize

patented

technology

to enzymatically

dissolve hair samples

and then perform

radioimmunoyassays on the hair sampled with confirmation

testing

by mass spectrometry

The Companys primary application

of its patented

technology

is as

testing

service that analyzes hair

samples

for the presence

of certain

drugs of abuse Employing radioimmunoassay

procedures

to drug test hair

samples

differs from the more commonly used

approach

in which immunoassay

procedures

are employed to

test urine samples The Companys tests provide quantitative

information

that

can

indicate the approximate

amount of drug ingested as well

as historical

data which can

show

pattern of

individual drug

use over

longer period of time providing

superior detection compared to other

types of drug testing This information

is

useful

to employers

for both applicant

and employee testing as well

as

to physicians

treatment professionals

law enforcement

agencies

school administrators

parents concerned

about

their childrens

drug use and other

individuals

or entities

engaged

in any business where drug

use or potential drug

use is an issue The Company

provides commercial

testing

and confirmation

by mass spectrometry using industry-accepted

practices for

cocaine marijuana PCP methamphetamine
sporadic use patterns and rapid clearance

hydromorphone

and oxycodone

including

Ecstasy which is difficult

to detect

in urine due to

from the body and opiates including

heroin hydrocodone

Testing services are currently performed at the Companys laboratory

at 5832 Uplander Way Culver City

California The Companys services are marketed under
registered service mark

the name RIAH Radioimmunoassay

of Hair

Development

of Radioimmunoassay

of Hair

The application

of unique

radioimmunoassay

procedures

to the analysis of hair was initially developed

in

1978 by the founders

of the Company Annette

Baumgartner

and Werner

Baumgartner Ph.D The

Baumgartners

demonstrated

that when

certain

chemical

substances

enter

the bloodstream the blood

carries

these substances

to the hair where they become entrapped in the protein matrix in amounts approximately

proportional

to the amount

ingested The Companys patented

drugs of abuse

testing

procedure

involves

direct

analysis of

liquefied

hair samples

by radioimmunoassay

procedures

utilizing

effective

reagents

and antibodies

The antibodies detect

the presence

of

specific

drug or drug metabolite

in the liquefied

hair sample by

reacting with the drug present

in the sample solution

as well

as

an added radioactive

analog

of

the drug The

resulting antibody-drug

complex is precipitated

and analyzed The amount of drug present

in the sample is

inversely

proportional

to the amount of radioactive

analog

in the precipitate RIA positive results are then

confirmed

by Mass Spectrometry

Depending upon the length of head hair

the Company is able to provide

historical

information

on drug use by the

person

from whom the sample was obtained

Since head hair grows

approximately

1.3 centimeters per month

3.9 centimeter head hair sample can

reflect

drug

ingestion over

the approximate

several months prior to the collection

of the sample Another testing

option involves

sectional

analysis of

the head hair sample In this procedure the hair is sectioned

lengthwise

to approximately

correspond

to certain

time periods Each

section corresponds

to

time period which allows the Company to

provide information

on patterns of drug use

Validation

of

the Companys Proprietary Testing Method

The process of analyzing human hair
been the subject of numerous peer-reviewed

for

the presence

of drugs using the Companys patented method has

scientific

field studies Results from the studies that have

been

published or accepted
technology Some of these studies were performed with the following

journals are generally

in scientific

for publication

favorable to the Companys

organizations

Boston University

School

of Public Health Citizens for

Better Community Court Columbia University

Connecticut

Department of

Mental Health

and Addictive

Services

Koba Associates-DC Initiative

Harvard Cocaine Recovery Project

Hutzel Hospital

ISA Associates

Interscience America-NIDA Workplace Study University

of California-Sleep

State Organization Maternal/Child

Substance

Abuse Project Matrix Center National Public Services

Research

Institute

Narcotic

and Drug Research

Institute San Diego State University-Chemical

Dependency

Center

Spectrum Inc Stapleford Centre London Task Force

on Violent Crime Cleveland Ohio University

of

Miami-Department of Psychiatry University

of Miami-Division of Neonatology

University

of South Florida-

Par Inc University

Operation
Ana and Wayne State University

of Washington VA Medical Center-Georgia

U.S Probation Parole-Santa

The

above studies include research

in the following

areas

effects of prenatal

drug use treatment evaluation workplace

drug use the criminal

justice

system and epidemiology Many of

the studies have been funded by the National
NIDA Several
supporting the general validity

hundred research

and usefulness of hair analysis

Institute

of Justice

or the National

Institute

on Drug Abuse

articles written by independent

researchers have been published

Some of

the Companys customers

have also completed their own testing

to validate the Companys

proprietary hair testing method as

prelude to utilizing

the Companys services These

studies have

consistently

confirmed

the Companys superior detection rate compared to urinalysis

testing When

results

based

on the Companys patented hair testing method were compared to urine results

in side-by-side

evaluations

to 10 times as many drug

abusers were accurately identified

by the Companys proprietary

method

offers

In addition to these studies the Companys proprietary method is validated through
for whom it has performed testing

of clients

to the thousands

the services it

In 1998

the National

Institute

of Justice utilizing Psychemedics hair testing completed

Pennsylvania

Prison study where hair analysis revealed

an average prison drug use level of approximately

7.9% in 1996

Comparatively urinalysis

revealed

virtually

no positives After measures to curtail drug use were instituted

drug-sniffing dogs searches

and scanners

the use level

fell

to approximately

hair analysis in 1998 Again

the urine tests

showed

virtually

no positives

of hair analysis to monitor populations

and the weakness

of urinalysis

2% according
The study illustrates

to the results of

the usefulness

The Company

FDA on all

has received

510k

clearance

from the United

States

Food

and Drug Administration

five of

its assays used

to test human hair for drugs of abuse As of

the date of

this report

Psychemedics

has received FDA clearance

for

five-drug panel

test

that

is not

restricted

to head hair samples

for drugs of abuse

Advantages

of Using the Companys Patented Method

The Company asserts

that hair testing

using its patented method confers substantive advantages

relative

to existing means of drug detection through

urinalysis Although urinalysis

testing

can provide accurate

drug

use information

the scope

of the information

is short-term and is generally limited to the type of drug

ingested within

few days of the test Studies published in many scientific

publications

have

indicated that

most drugs

disappear

from urine within

few days

In contrast

to urinalysis

testing hair testing

historical

drug

use information

resulting in

using the Companys patented method can provide long-term
This window may

wider window of detection

significantly

be several months or longer depending on the length of

the hair sample The Companys standard

test

offering however

uses

3.9 centimeter

length head hair sample

cut close to the scalp which measures

use for

approximately

the previous several months

This wider window

enhances

the detection efficiency

of hair analysis making it particularly

useful

in

pre-employment and random testing Hair

testing

not only identifies more drug users but

it may also uncover

patterns and severity of drug use information

most helpful

in determining

the scope

of an individuals

involvement

with drugs while serving as

deterrent against

the use of drugs Hair

testing employing the

Companys patented method greatly reduces

the incidence

of

false negatives associated with evasive

measures typically

encountered

with urinalysis testing For example urinalysis

test

results

are adversely

impacted

by excessive

fluid intake prior to testing

and by adulteration

or substitution

of

the urine sample

Moreover

drug user who abstains from use for

few days prior to urinalysis

testing

can usually escape

detection Hair

testing

is effectively

free of these problems as

it cannot

be thwarted

by evasive measures

typically encountered

with urinalysis

testing Hair

testing

is also attractive

to customers

since sample

collection

is typically

performed

under

close supervision

yet is less intrusive

and less embarrassing

for test

subjects

Hair

testing

using the Companys patented method with mass spectrometry

confirmation

further reduces

the prospects

of error in conducting

drug detection tests Urinalysis testing

is more susceptible to problems

such

as evidentiary

false positives

resulting from passive

drug exposure

or poppy seeds To combat

this

problem in federally mandated testing the opiate cutoff

levels

for urine testing were raised 667% from

300 to 2000 ng/ml

on December

1998 and testing

for the presence

of

heroin metabolite 6-AM was

These requirements

required
6-AM in urine down to several hours post drug use In contrast
be detected

for months

effectively

however

reduced

the detection time frame

for confirmed

heroin with

the metabolite 6-AM is stable

in hair and can

In the event

positive urinalysis

test

result

is challenged

test on

newly collected urine sample is not

viable remedy Unless

the forewarned

individual continues

to use drugs prior to the date of

the newly

collected sample

re-test may yield

negative

result when using urinalysis

testing

because

of temporary

abstinence

In contrast when

the Companys hair testing method is offered on

repeat hair sample the

individual suspected

of drug use cannot

as easily

affect

the results

because

historical

drug use data remains

locked

in the hair fiber

When

compared to other hair testing methods

not only are the Companys assays

cleared by the FDA

they also employ

unique

patented method of enzyme

digestion that

the Company believes allows for the

most efficient

release of drugs

from the hair without destroying the drugs The Companys method of

releasing

drugs

from hair

is

key advantage

and results

in superior detection rates

Disadvantages

of Hair Testing

There are

some disadvantages

of hair testing

as compared to drug detection through

urinalysis Because

hair starts growing below the skin surface drug ingestion evidence

does not appear

in hair above

the scalp

until approximately

five to seven

days after use

Thus hair

testing

is not suitable

for determining

drug presence

in for cause testing

as

is done in

connection

with an accident

It does however

provide

drug history which can complement

urinalysis

information

investigation
in for cause testing

Currently

radioimmunoassay

testing

using hair samples

under

the Companys patented method is only

practiced by Psychemedics Corporation

The Companys prices for its tests are generally

somewhat

higher

than prices for tests using urinalysis

but

the Company believes that

its superior detection rates provide more value

to the customer This pricing

policy could however

adversely impact

the growth of the Companys sales volume

Intellectual Property

Certain aspects of the Companys hair analysis method are covered

by six US patents and

number of

foreign patents and trade secrets

owned by the Company One U.S patent expires in 2011 see risk factors

and two additional patent applications

have been filed The Company believes that

its superior

technology

is

protected by this combination

of US and foreign patents and trade secrets The Companys ability

to protect

the confidentiality

of

these trade secrets

is dependent upon

the Companys internal

safeguards

and upon

the

laws protecting trade secrets

and unfair competition

Target Markets

Workplace

The Company focuses
applicant and employee testing

its primary marketing

efforts

on the private sector with particular

emphasis on job

Most businesses

use drug testing

to screen job applicants and employees

The Hazeldon Foundation

survey

from 2007 indicated that

85 percent

of human resource

professionals believe that drug

testing

is an

effective

way to diagnose

substance

abuse The prevalence

of drug

screening

programs reflects

concern

that

use contributes

drug
HR professionals believe that absenteeism

to employee health problems and costs as the same study found that 62 percent

of

is the most significant

problem caused

by substance

abuse

and

addiction

followed

at 49 percent

by reduced

productivity

lack of trustworthiness

at 39 percent

negative

impact

on the companys external

image at 32 percent

and missed deadlines at 31 percent

and in certain

industries safety hazards It has been estimated that

the cost

to American businesses

is more than

$100 billion annually

The principal criticism of employee drug

testing

programs centers on the effectiveness of

the testing

program Most private sector testing

programs use urinalysis Such programs are susceptible to evasive

maneuvers and the inability
An industry has developed
dilutants clean urine and devices

over

to obtain confirmation

through

repeat samples

in the event of

challenged

result

the Internet

and through

direct mail marketing

wide variety of adulterants

to assist drug users in falsifying

urine test results

Moreover

scheduled

tests such

as pre-employment testing

and some random testing

programs provide an

opportunity

for many drug users to simply abstain for

few days in order

to escape

detection by urinalysis

The Company presents its patented hair analysis method to potential

clients

as

better

technology

well

suited to employer needs Field studies

and actual client

results

support

the accuracy

and effectiveness

of the

Companys patented

technology

and its ability

to detect varying levels of drug use This information

provides

an employer with greater

flexibility in assessing

the scope

of an applicants

or an employees

drug problem

The Company performs

confirmation

test of all presumptive

positive results

through mass spectrometry

The use of mass spectrometry

is an industry accepted

practice used

to confirm positive drug test

results of an

initial screen

In an employment

setting mass spectrometry confirmation

is typically used prior to the taking

of any disciplinary action against an employee

The Company offers

its clients

five-drug screen with mass

spectrometry

confirmation

of cocaine PCP marijuana amphetamines

including

Ecstasy and opiates

including

heroin and oxycodone

Schools

The Company currently serves hundreds

of schools

throughout

the United

States and in several

foreign

countries

The Company

offers

its school

clients

the same five-drug screen with mass spectrometry

confirmation

that

is used with the Companys workplace testing

service

Parents

The Company also offers

personal drug testing

service known as PDT90 for parents concerned

about

drug use by their children

It allows parents to collect

small sample from their child in the privacy of

it to the Companys laboratory
service uses the same patented method that

and have it tested for drugs of abuse

by the Company

The

is used with the Companys workplace

testing

the home send

PDT-90

service

testing

Research

The Company

is involved in ongoing studies involving

use of drugs of abuse

in various populations

including
North Carolina Chapel Hill Johns Hopkins Bloomberg School Of Public Health Mclean Hospital Wayne

Boston Medical Center Boston University

School of Public Health University

the following

of

State University

and Chemistry

and Drug Metabolism Section NIDA

Sales and Marketing

The Company markets

its corporate drug testing

services primarily through

its own sales

force Sales

offices are located in several major cities in the United States in order

to facilitate communications with

corporate employers The Company markets

its home drug testing

service PDT-90 through

the Internet

and

retail distributors

Competition

The Company competes directly

with numerous commercial

laboratories

that

test

for drugs primarily

through

urinalysis testing Most of

these laboratories

such

as Laboratory Corporation

of America and Quest

Diagnostics

have

substantially

greater

financial

resources market identity marketing

organizations

facilities

and numbers of personnel

than the Company

The Company has been steadily

increasing its base of corporate

customers

and believes that

future success with new customers

is dependent

on the Companys ability

to

communicate

the advantages

of implementing

drug program utilizing

the Companys patented hair analysis

method

The Companys ability

to compete is also

function of pricing The Companys prices for

its tests are

generally

somewhat

higher

than prices for tests using urinalysis However

the Company believes that

its

superior detection rates coupled with the customers ability to test

less frequently

due to hair

testings wider

window of detection several months versus approximately

three days with urinalysis provide more value

to

the customer This pricing policy could however

lead to slower

sales growth for

the Company

Although other

laboratories also offer hair testing

for drugs of abuse Psychemedics

is the only laboratory

with FDA clearance

for

five-drug panel

test

that

is not

limited to head hair

samples

date no other laboratory

engaged

in hair testing

has received

approval

or clearance

its assays

for the testing

of both head and body hair samples

two other

laboratories

for drugs of abuse To
from the FDA on all of
have either partial FDA

clearance

or clearance

specific

to head hair samples only Additionally several of these laboratories

that

purport

to test hair samples

use method that

the Company presumes includes the use of

form of

immunoassay

procedures

The Company

however

does not believe that

immunoassay

testing of hair samples

is as effective

on

commercial basis without using the Companys unique

patented method which allows for

the efficient

release of drugs

from the hair through

enzyme

digestion without destroying the drugs

Government Regulation

The Company is licensed as

clinical

laboratory by the State of California as well

as certain

other states

All

tests are performed according

to the laboratory

Human Services

through

the Clinical Laboratories

licensing statutes

standards

established by the Department of Health

Improvement Amendments CLIA and various

and

state

substantial

number of states

regulate drug

testing The

scope

and nature of such

regulations

varies

greatly from state

to state

and is subject

to change

from time to time The Company addresses

state

law issues

on an ongoing basis

In 2000 the FDA issued regulations

under

the Federal Food Drug and Cosmetic Act

as amended

the

FDC Act with respect
the regulations

not previously

recognized

to companies that market drugs of abuse

test sample

collection systems Under

companies engaged

in the business
by the FDA are required to submit

testing

of

for drugs of abuse using

test screening

assay

their

assay to the FDA for recognition prior to

marketing In addition

the laboratory performing

the tests is required to be certified

by

recognized

agency

The regulations

included

transitional

period in order

for companies not

immediately

in compliance with the

proposed requirements

to obtain the necessary

data they needed for submission

to the FDA

By May

2002 the Company had received

510k

clearance

to market all

five of

its assays

In June 2008 Psychemedics also received

the first CAP College of American Pathologists

certification

specifically

including hair testing

Research and Development

The Company is continuously

engaged

in research

and development

activities

During the years ended

December

31 2010 2009 and 2008 $481433 $467435 and $474622 respectively were expended for

research

and development

The Company continues

to perform research

activities

to develop

new products

and

services and to improve existing products

and services utilizing

the Companys proprietary

technology

The

Company also continues

to evaluate methodologies

to enhance

its drug

screening

capabilities Additional

research using the Companys proprietary

technology

is being

conducted

by outside research

organizations

through

government-funded

studies

Research

has continued

on the interactions

of different

types of hair with drugs

in the environment and

from actual drug usage This work has concentrated

on assessments

of various published methods for removal

of externally deposited

drug

from hair surfaces and on methods of extraction of metabolically

deposited

drugs

from the solid hair matrix Some of the work has been presented

at meetings

of the Society of Forensic

Toxicologists

and the European Society of Hair Testing

Sources and Availability

of Raw Materials

Since its inception

the Company has purchased

raw materials for

its laboratory

services from outside

suppliers

The most critical of

these raw materials are the radio-labeled

drugs which the Company

purchases

from single supplier

although

other suppliers of radio-labeled

drugs exist The Company has entered

into an

agreement with its principal supplier

to purchase

certain proprietary

information

regarding the manufacture

of

such

radio-labeled

drugs

owned

by the supplier

in the event

that

the supplier ceases to be able to supply such

radio-labeled

drugs

to the Company

Employees

As of December

31 2010 the Company had 91 full-time

equivalent employees

of whom full-time

employees were in research

and development

None of the Companys employees are subject

to

collective

bargaining agreement

Item 1A Risk Factors

In addition to other

information

contained

in this Form 10-K the following

risk factors

should

be

carefully considered

in evaluating Psychemedics Corporation

and its business

because

such

factors

could

have

significant

impact

on our business

operating results

and financial

condition

These risk factors

could

cause

actual

results

to materially differ

from those projected in any forward-looking

statements

Companies may develop

products

that compete with our products

and some of these companies may be

larger and better capitalized

than we are

Many of our competitors

and potential

competitors are larger

and have greater

financial

resources

than

we do and offer

range of products

broader

than our products Some of the companies with which we now

compete or may compete in the future may develop more extensive research

and marketing

capabilities

and

greater

technical

and personnel

resources

than we do and may become

better positioned to compete in an

evolving

industry Failure to compete successfully could

harm our business

and prospects

Increased competition including

price competition

could have

material

impact on the Company

net

revenues and profitability

Our business

is intensely

competitive

both in terms of price and service Pricing of drug

testing

services

is

significant

factor often considered

by customers

in selecting

drug testing

laboratory As

result of

the

clinical

laboratory

industry

undergoing

significant

consolidation

larger clinical

laboratory

providers are able to

increase cost efficiencies

afforded by large-scale automated testing This consolidation

results

in greater price

competition

The Company may be unable

to increase cost efficiencies

sufficiently

if at all and as

result

its

net earnings and cash

flows could

be negatively impacted by such

price competition

The Company may also

face increased

competition

from companies that do not comply with existing laws or regulations or otherwise

disregard compliance

standards

in the industry Additionally

the Company may also face changes

in fee

schedules

competitive

bidding for

laboratory

services or other actions or pressures reducing

payment

schedules

as

result of

increased

or additional

competition

Additional

competition

including

price

competition could

have

material adverse

impact

on the Companys net revenues

and profitability

Our results of operations are subject

in part

to variation in our customers hiring practices and other

factors

beyond our control

Our

results of operations have been and may continue

to be subject

to variation in our customers hiring

practices which in turn is dependent

to

large extent

on the general condition

of

the economy Results for

particular quarter may vary due to

number of factors

including

economic conditions

in our markets

in general

economic conditions

affecting

our customers

and their particular industries

the introduction

of new products

and product

enhancements by us or our competitors

and

pricing and other competitive

conditions

failure to obtain and retain new customers or

loss of existing customers or

reduction

in tests

ordered could impact the Company

ability to successfully

grow its business

The Company

needs

to obtain and retain new customers In addition

reduction in tests ordered without

offsetting

growth in its customer

base could

impact

the Companys ability

and could

have

material adverse

impact

on the Companys net revenues

to successfully grow its business
and profitability

We compete

primarily on the basis of the quality of testing reputation in the industry

the pricing of services and ability

to

employ qualified personnel

The Companys failure to successfully

compete on any of these factors

could

result

in the loss of customers

and

reduction in the Companys ability

to expand its customer

base

Our business

could be harmed if we are unable to protect our proprietay technology

We rely primarily on

combination

of

trade secrets patents and trademark

laws

and confidentiality

procedures

to protect our technology

Despite

these precautions

unauthorized

third

parties may infringe or

copy portions of our

technology

In addition

because

patent applications

in the United States are not publicly

disclosed until either

18 months after

the application filing date or

the publication

date of an issued

patent wherein applicants seek only US patent protection
which relate to our

there is

technology

Moreover

risk that

applications not yet disclosed may have been filed

foreign intellectual

property laws will not protect

our

intellectual

property

rights

to the same extent as United States intellectual

property laws One of our

patents is due to expire in 2011
be vulnerable to competitors who attempt

In the absence

of protections afforded by patents or by trade secrets we may

to copy our products

processes

or technology

Our business

could be affected by

computer

or other IT System failure

computer or IT system failure could

affect our ability to perform tests report

test

results

or properly

bill customers Failures could

conversions

telecommunications

occur

as

result of the standardization

and other system
failures malicious human acts such as electronic break-ins or computer

IT systems

of our

viruses

or natural disasters Sustained

system failures

or interruption of

the Companys systems

in one or

more of

its operations could disrupt the Companys ability

to process

and provide test

results

in

timely

manner and/or bill

the appropriate party Failure of

the Companys information

systems

could adversely affect

the Companys business

profitability

and financial

condition

Failure to maintain confidential

information

could result in

signficant

financial

impact

The Company maintains confidential

information

regarding the results of drug

tests and other

information

including

credit

card and payment

information

from our customers The failure to protect

this information

could

result

in lawsuits

fines or penalties Any loss of data or breach of confidentiality such

as through

computer

security

breach could

expose

the Company to

financial

liability

Our future

success will depend

on the continued services of our key personnel

The loss of any of our key personnel

could

harm our business

and prospects We may not be able to

attract

and retain

personnel

under

contract other

than

necessary
officers who have

for the development

of our business We do not have key personnel

agreements

providing

for severance

and non compete covenants

in the event of

termination

of employment

following

change

of control

Further we do not have

any key

man life insurance

for any of our officers

or other key personnel

We may become
and attestation process mandated on certain

exposed to potential

risks

and related costs as

result of the internal control

assessment

issuers by Section

404 of the Sarbanes-Oxley Act of 2002

We evaluated

tested

and implemented

internal

controls over

financial

reporting to enable management

to

report on such
we cease qualifying as

internal

controls as

required by Section

the Sarbanes-Oxley
smaller reporting company under SEC rules under

404 of

Act of 2002 At such

time

$75 million market cap we

will be required to provide an auditor attestation

on internal

controls

The auditor attestation

could

cause

us to

incur significant

costs including

increased

accounting

fees and staffing

levels While we believe that we are

compliant with the management

evaluation requirements of Section 404 if our

independent

registered public

accounting

firm were unable

to attest

in

timely manner

to our evaluation

we could

be subject

to regulatory

scrutiny

and

loss of public confidence

in our internal

controls

In addition

new or improved controls

or difficulties

encountered

in their

or cause

us to fail

to meet our

reporting obligations

implementation could

any failure to implement required
harm our operating results

Our reliance on one supplier

for certain raw materials used in our testing procedures could harm our

business

and prospects

Since

its inception

the Company has purchased

raw materials for

its laboratory

services from outside

suppliers

The most critical of these raw materials are the radio-labeled drugs which the Company

purchases

from single supplier

although

other suppliers of radio-labeled

drugs exist The Company has entered

into an

agreement with its principal supplier

to purchase

certain

proprietary

information

regarding the manufacture

of

such

radio-labeled

drugs owned by the supplier

in the event

that

the supplier ceases to be able to supply such

radio-labeled

drugs

to the Company Obtaining alternative

sources of supply of

the radio-labeled

drugs

could

involve delays and other costs however

the Company maintains

surplus supply The failure of the

Companys primary or any alternative

supplier of

radio-labeled drugs

to provide such

radio-labeled

drugs at an

acceptable

price or an interruption of supplies from such

supplier

and

the exhaustion

of the Companys

current supply on hand could

result

in lost or deferred sales

There is

risk that our insurance

will not be sufficient

to protect

us from errors and omissions liability or

other claims or

that

in the future

errors and omissions

insurance

will not be available

to us at

reasonable

cost

if at all

Our business

involves

the risk of claims of errors

and omissions

and other claims inherent

to our

business We maintain errors and omissions and general

liability insurance

subject

to deductibles

and

exclusions

There is

risk that our

insurance will not be sufficient

to protect us from all

such possible claims

An under-insured

or uninsured

claim could

harm our operating results

or financial

condition

Our research

and development

capabilities

may not produce viable new services or products

We are attempting to develop

further capabilities

in the drug

testing

arena It

is uncertain whether we will

be able to develop

services that

are more efficient

effective

or that are suitable

for our customers Our ability

to create viable products

or services depends on many factors

including

the implementation

of appropriate

technologies

the development

of effective

new research

tools the complexity

of

the chemistry

and biology

the lack of predictability

in the scientific

process

and the performance

and decision-making

capabilities

of our

scientists

Further

some of our existing patents are due to expire within the next

years including one in 2011

Our

research

and development

teams are working to develop

improved processes with the aim of gaining

additional patent protection

There is no guarantee

that

they will be successful

in developing

these

improvements

or gaining such additional patent protection

If any or all of our patents expire there may be

increased

competition

in the marketplace

for our service or we might be required to

rely

to

greater extent on

trade secret protection

Improved

testing technologies

or the Companys customers using new technologies

to perform their own

tests could adversely affect

the Companys business

Advances

in technology

may lead to the development

of more cost-effective

technologies

such

as point-

of-care testing

equipment

that

can be operated

by third

parties

or customers

themselves

in their own offices

without

requiring the services of

freestanding laboratory Development

of such

technology

and its use by the

Companys customers

could

reduce

the demand

for its testing

services and negatively

impact

our revenues

We may not be able to recruit and retain the experienced

scientists

and management we need to compete in

our industry

Our future success depends upon our ability

to attract

retain

and motivate highly

skilled

scientists

and

management Our ability

caliber scientists

to achieve

our business
and other qualified experts We compete with other

strategies

depends on our ability

to hire and retain high

testing

companies

research

companies

and academic and research

institutions

to recruit

personnel

personnel

We may incur greater costs

than anticipated

and face significant
or may not be successful

competition

for

qualified

in attracting

new scientists

or management

or in retaining or motivating

our existing personnel

Our

future success also depends on the personal efforts

and abilities of the principal members

of our

senior management

and scientific

staff

to provide strategic direction to manage

our operations and maintain

cohesive

and stable

environment

Our facilities

and practices may fail to comply with government

regulations

Our

testing

facilities

and processes must be operated

in conformity with current government

regulations

These requirements

include

records and documentation

among other things quality control quality assurance
If we fail
to comply with these requirements

and the maintenance

of

we may not be able to continue

our

services to certain customers or we could

be subject

to fines and penalties

suspension

of production

or

withdrawal

of our certifications

We operate

facility

that we believe conforms

to all applicable requirements

This facility

and our

testing

practices are subject

to periodic regulatory

inspections

to ensure

compliance

Our business

could be harmed from the loss or suspension

of any licenses

The forensic laboratory

testing

industry is subject

to significant

regulation and many of

these statutes

and

regulations are subject

to change

The Company cannot

assure that applicable

statutes

and regulations will not

be interpreted or applied by

regulatory authority in manner that would adversely affect

its business

Potential sanctions for violation of

these regulations could

include the suspension

or loss of various licenses

certificates

and authorizations

which could

have

material adverse

effect

on the Companys business

If our use of chemical and hazardous materials
injury we may be liable for damages

violates

applicable

laws or regulations or causes personal

Our drug testing

activities

including

the analysis and synthesis of chemicals involve

the controlled use

of chemicals including

flammable combustible toxic and radioactive materials that are potentially

hazardous

Our use storage handling and disposal of these materials is subject

to federal

state

and local

laws and

regulations

including

the Resource Conservation

and Recovery Act

the Occupational

Safety and Health Act

and local

fire codes and regulations promulgated by the Department of Transportation

Agency the Department of Energy

and the California Department of Public Health

the Drug Enforcement
and Environment We may

incur significant

costs to comply with these laws and regulations in the future In addition

we cannot

completely

eliminate the risk of accidental

contamination

or injury from these materials which could

result

in

material unanticipated

expenses such

as substantial

fines or penalties

remediation

costs or damages

or the

loss of

permit or other authorization

to operate

or engage in our business

Those

expenses

could exceed our

net worth and limit our ability

to raise additional capital

Our operations could be interrupted

by damage to our specialized laboratory

facilities

Our operations are dependent

upon the continued

use of our highly

specialized laboratories

and

equipment

in Culver City California Catastrophic

events

including

earthquakes

fires or explosions

could

damage our

laboratories

equipment

scientific

data work in progress or inventories of chemicals

and may

materially interrupt

our business We employ

safety

precautions in our

laboratory

activities

in order

to reduce

the likelihood of

the occurrence

of certain

catastrophic

events

however we cannot

eliminate the chance

that

such

events will occur The availability

of

laboratory

space

in these locations is

limited and rebuilding

our

facilities

could

be time consuming

and result

in substantial

delays in

fulfilling our agreements

with our

customers We maintain business

interruption insurance

to cover

continuing

expenses

and lost

revenue

caused

by such

occurrences

However

this insurance

does

not compensate us for the loss of opportunity

and potential

harm to customer

relations

that our

inability

to meet our customers needs

in

timely manner could

create

Agreements

we have with our employees

our trade secrets

confidential

information

consultants and customers may not afford adequate protection for
and other proprietary

information

In addition to patent protection

we also rely on copyright

and trademark

protection

trade secrets know-

how continuing technological

innovation

and licensing opportunities

In an effort

to maintain the

confidentiality

and ownership of our trade secrets

and proprietary

information

we require our employees

consultants

and advisors to execute

confidentiality

and proprietary

information

agreements However

these

agreements may not provide us with adequate

protection against

improper use or disclosure of confidential

information

and there may not be adequate
Furthermore we may from time to time hire scientific

remedies

in the event of unauthorized

use or disclosure

personnel

formerly

employed by other companies

involved in one or more areas similar to the activities

we conduct

In some situations our confidentiality

and

proprietary

information

agreements may conflict with or be subject

to the rights

of third parties with whom

10

our employees

consultants or advisors have prior employment

or consulting

relationships Although we

require our employees and consultants to maintain the confidentiality

of all proprietary

information

of

their

previous employers these individuals

or we may be subject

to allegations of

trade secret misappropriation

or

other similar claims as

result of their prior affiliations

Finally others may independently

develop

substantially

equivalent proprietary

information

and techniques

or otherwise gain access

to our trade secrets

Our

failure or inability

to protect our proprietary

information

and techniques may inhibit

or limit our ability to

compete effectively or exclude

certain competitors

from the market

Risks Related to Our Stock

Our quarterly operating

results could fluctuate

significantly which could cause our stock price to decline

Our quarterly operating results

have fluctuated in the past and are likely

to fluctuate

in the future Our

results

are

impacted

by the extent

to which we are able to gain new customers

and on the hiring practices of

our existing customers which are in turn

impacted

by general economic conditions

Entering into new

customer

contracts can

involve

long lead time Accordingly negotiation can be lengthy

and is subject

to

number of significant

risks including

customers budgetary

constraints

and internal

reviews Due to these and

other market factors

our operating results

could

fluctuate

significantly

from quarter

to quarter

In addition

we

may experience
industry-specific economic conditions

significant

fluctuations

in quarterly operating results

due to factors

such

as general and

that may affect

the budgets

and the hiring practices of our customers

Due to the possibility

of

fluctuations

in our

revenue

and expenses we believe that quarter-to-quarter

comparisons

of our operating results are not necessarily

good indication

of our future performance Our

operating results

in some quarters may not meet

the expectations

of stock market analysts and investors

If we

do not meet analysts

and/or

investors

expectations

our stock price could

decline

Our stock price could experience

substantid

volatility

The market price of our common stock

has historically

experienced

and may continue

to experience

extensive volatility

Our quarterly operating results the success or failure of future development

efforts

changes

in general conditions

in the economy

or the financial markets

and other developments

affecting

our

customers our competitors or us could

cause

the market price of our common stock

to fluctuate

substantially

This volatility may adversely affect

the price of our common stock

In the past securities

class

action

litigation

has often been instituted

following

periods of volatility

in the market price of

companys

securities

securities

class

action suit against us could

result

in potential liabilities substantial costs and the

diversion of managements

attention and resources

regardless of whether we win or lose

Payment of

dividend

could decline or cease

Because we have historically

paid dividends

any cessation of our program or reduction in our quarterly

dividend could

affect our stock price We have paid dividends

on our common stock

for 58 consecutive

quarters It

is our

intent

to continue

this practice as

long as we are able However

if we are forced to cease

this practice or reduce

the amount of the regular dividend due to operating or economic

conditions

our stock

price could

suffer In December

2008 the Company also paid

special dividend Investors should

not

anticipate

or expect

any future or recurring special dividends

Further

if the Company

ceases its future

dividends

return on investment

in our common stock would depend

entirely

upon future appreciation

There

is no guarantee

that our common stock will appreciate in value or even maintain the price at which

stockholders

have

purchased

their shares

The general economic

condition

could

continue

to deteriorate

Our business

is dependent

upon new hiring and the supply of new jobs created by overall economic

conditions

If the economy

continues

to deteriorate

leading to high unemployment

and the lack of new job

creation our business

and stock price could

be adversely affected

11

Item lB Unresolved

Staff Comments

Not applicable

Item

Properties

The Company maintains its corporate office

and northeast

sales

office

at 125 Nagog Park Acton

Massachusetts

the office

consists of 3971

square

feet and

is leased through

February

2015

The Company leases 18000

square feet of space

in Culver City California for laboratory purposes This

facility

is leased through

December

31 2012 with an option to renew for an additional

three years The

Company also leases an additional 5400 square feet of space
and information

purposes This office

technology

space

in Culver City California for customer service

is leased through

December

31 2012 with an option

to renew for an additional

three years

Item

Legal Proceedings

The Company

is involved in various suits and claims in the ordinary

course of business

The Company

does

not believe that

the disposition

of any such

suits or claims will have

material adverse

effect

on the

continuing

operations or financial

condition

of

the Company

Item

Reserved

Not applicable

12

PART II

Item Market for Registrants Common Equity Related Shareholder Matters and Issuer Purchases of
Equity Securities

The Companys common stock

is traded on the NASDAQ Stock Market

under

the symbol PMD As

of March

25 2011 there were 217 record holders of

the Companys common stock

The number of

record

owners was determined

from the Companys stockholder

records maintained

by the companys transfer

agent

and does not

include beneficial

owners of the Companys common stock whose

shares are held in the names

of various security holders dealers and clearing agencies

The Company believes that

the number of beneficial

owners of

the Companys common stock held by others as or in nominee names

exceeds

2000

The following

table

sets

forth

for the periods indicated the range of prices for

the Companys common

stock

as

reported by the NASDAQ Stock Exchange

and dividends

declared

by the Company

Fiscal 2009

First Quarter

Second Quarter

Third Quarter

Fourth Quarter

Fiscal 2010

First Quarter

Second Quarter

Third Quarter

Fourth Quarter

High

Low

Dividends

$7.32

$3.03

$0.170

6.99

7.05

7.70

5.51

6.00

5.10

0.170

0.120

0.120

$8.21

$7.17

$0.120

9.03

9.72

9.95

7.54

7.76

6.89

0.120

0.120

0.120

The Company has paid dividends over

the past fourteen years It most recently declared

dividend in

March 2011 which was paid in March

2011

The Companys current

intention is to continue

to declare

dividends

to the extent

funds are available and not required for operating purposes

or capital

requirements

and only then upon

approval

by the Board of Directors

Issuer Purchases of Equity Securities

During the fourth quarter of 2010 the Company repurchased

822 common shares for

treasury at

weighted

average price of $7.31 per

share

See Item

for more detail

13

EQUITY COMPENSATION

PLAN INFORMATION

The following

table

provides information

as of December

31 2010 with respect

to shares of

the

Companys common stock
Equity Incentive Plan

that were issuable under

the Companys 2006 Equity Incentive Plan the 2006

The table

does not

include information with respect

to shares subject

to outstanding options granted

under other equity compensation

plans that were no longer

in effect

on December

31 2010

Footnote

to

the table

sets

forth

the total number of shares of common stock

such

expired or discontinued

plans as of December

issuable upon
31 2010 and the weighted

the exercise of options under

average exercise price of

those

options No additional options may be granted

under

such

other expired or discontinued

plans

Number of Securities
to
Be Issued Upon Exercise
of

Outstanding

Options

Weighted

Average

Exercise

Price of Outstanding

Number of Securities

That

Options Warrants

and

Remained

Available

for

Plan Category

Equity compensation

plans approved

by security holders

Equity compensation plans not

approved

by security holders

Total

Warrants and Rights

Rights

Future

Issuance

94700

$0.00

84450

94700

$0.00

84450

Consists of

the 2006 Equity Incentive Plan

This table

does not
May 11 2006 As of December
the exercise of outstanding options under

include information

31 2010

for

the Companys 2000 Stock Option

Plan discontinued

on

total of 289371

the foregoing discontinued

shares of common stock were issuable upon
average exercise

plan The weighted
per share No additional options may be granted

price of outstanding options under

such plan is $13.96

under

the 2000 Stock Option Plan

Performance Graph

COMPARE YEAR CUMULATIVE

TOTAL RETURN AMONG

PSCYCHEMEDICS CORPORATION NASDAQ COMPOSITE
INDEX AND RUSSELL 2000 INDEX

200

150

100

50

Iii__

2005

2006

2007

2008

2009

2010

PSYCHEMEDICS

CORPORAF1ON

RUSSELL

2000

INDEX

NASDAQ COMPOSI

FL INDEX

Psychemedics Corporation

100.00

142.93

124.28

2005

2006

2007

Russell 2000

Index

NASDAQ Composite Index

100.00

121.40

106.90

100.00

109.52

120.27

71.51

102.89

2008

61.67

7458

2009

74.49

88.03

2010

82.25

107.83

12029

Calculated by the Company using www.vahoo.com/finance

historical

prices

aol

sa

endec

Dccc nhcr

31

2010

ci

Company

Daa

20 11
ommon Stock the Russell 2000 Index

oh

and the

\SDAQ

Composite Index The prices

all assume the reinvestment

of dividends

14

The Russell 2000 Index

is composed

of the smallest 2000 companies in the Russell 3000 Index The

Company has been

unable

to identify

peer group of companies that engage in

testing

of drugs of abuse

except

for

large pharmaceutical

companies where such

business

is insignificant

to such

companies

other

lines of businesses

The Company therefore uses in its proxy statements

peer

index based

on market

capitalization

The NASDAQ Composite Index
Exchange Market

includes companies whose

shares are traded on the NASDAQ Stock

In September 2008 Psychemedics moved its listing to the NASDAQ Stock Exchange

Market

from the AMEX Stock Exchange Market

Item

Selected

Financial Data

The selected financial

data presented

below is derived from our

financial

statements

and should

be read

in connection

with those

statements

Revenue

Gross profit

Income from operations

Net

income

Basic net income per share

Diluted

net income per share

Total assets

Working capital

Shareholders

equity

Cash dividends

declared

per common share

As of and for the Years

Ended

December

31

2010

2009

2008

2007

2006

In Thousands

Except

for per Share Data

$20109

$16955

$22949

$24569

$23425

12042

4414

2614

0.50

0.50

11766

8566

9748

0.480

9610

2584

1527

0.29

0.29

10602

8471

9294

0.530

13350

14677

14056

4707

2969

0.57

0.57

12628

9516

10560

7139

4484

0.86

0.85

15561

12773

13878

1.160

0.575

7563

4902

0.95

0.94

13261

10534

11504

0.475

Item

Managements Discussion

and Analysis

of Financial Condition and Results of Operations

The Managements

Discussion

and Analysis of Financial Condition

and Results of Operations

should

be

read together with the more detailed business

information

and financial statements

and related notes that

appear elsewhere

in this annual

report on Form 10-K This annual

report may contain certain

forward-looking information within the meaning of the Private Securities Litigation Reform Act of 1995

This information

involves risks and uncertainties

Actual

results may differ materially from the

results

discussed

in the forward-looking

statements

Factors

that might

cause

such

difference include

but are not

limited to those discussed

in Item 1A

Risk Factors

Overview

Psychemedics Corporation

is the worlds largest

provider of hair testing

for drugs of abuse utilizing

patented hair analysis method involving

radioimmunoassay

technology

and confirmation

by mass spectrometry

to analyze

human hair

to detect abused

substances

The Companys customers

include Fortune

500 companies

as well as small

to mid-size corporations

schools

and governmental

entities

located primarily in the United

States During the year ended December

31 2010 the Company generated

$20.1 million in revenue while

maintaining

gross margin of 60% and pre-tax margins

of 22% At December

31 2010 the Company had

$5.7 million of cash cash equivalents

and short-term investments

During 2010 the Company had operating

cash

flow of $3.3 million and it distributed approximately

$2.5 million or $0.48 per share of cash

dividends

to

its shareholders

To date the Company has paid fifty-eight

consecutive

quarterly cash dividends

15

The following

table

sets

forth for the periods indicated

the selected statements

of operations data as

percentage

of

total

revenue

Revenue

Cost of

revenue

Gross profit

Operating

expenses

General

and administrative

Marketing and selling

Research

and development

Total operating expenses

Operating

income

Other income

Interest

income

Other

income

Total other

income

Income before taxes

Provision

for income taxes

Net

income

Year Ended December

31

2010

2009

2008

100.0%

100.0%

100.0%

40.1%

43.3%

41.8%

59.9%

56.7%

58.2%

20.9%

21.2%

19.7%

14.6%

17.5%

__ __ _1

15.9%

37.9%

41.5%

22.0%

15.2%

37.7%

20.5%

0.1%

0.3%

1.3%

0.1%

0.3%

1.3%

15.5%

21.8%

9.1%

6.5%

8.9%

22 _2

Results

for the Year Ended DecembeE 31 2010 Compared to Results for the Year Ended December 31

2009

Revenue

increased

$3.2 million or 19% to $20.1 million in 2010 compared to $17.0 million in 2009 This

increase was due to an increase in volume from new and existing clients Average revenue

per sample

increased

2% between 2010 and 2009

Gross profit

increased

$2.4 million to $12.0 million in 2010 compared to $9.6 million in 2009 Direct

costs increased

by 10% from 2009 to 2010 mainly associated with the direct

cost of materials

resulting

from

higher volumes

The

gross profit margin increased

from 57% in 2009 to 60% in 2010 as revenue

increased

more than direct

costs

General and administrative GA expenses were $4.2 million for the year ended December

31 2010

compared to $3.6 million for

the year ended December

of revenue GA expenses were 20.9% and 21.2% for

31 2009 representing an increase of 17% As
31 2010
the years ended December

and

percentage

2009 respectively

The

increase in general and administrative

expenses

in 2010 was due to several

factors

an

increase in salary expense

due to the reinstatement of salaries

in 2010 following

salary

cut in the second

half of 2009 an increase in accounting

and audit

fees an increase in

legal

fees defending

our technology

on

behalf of our customers and bonuses

earned

in 2010 and not

in 2009

Marketing and selling

expenses were $2.9 million for

the

year

ended December

31 2010 compared to

$3.0 million for the

year

ended December

31 2009

decrease of less than 1% Total marketing

and selling

expenses

represented

14.6% and 17.5% of revenue

for the

years

ended December

31 2010 and 2009

respectively

Research and development RD expenses

2009 RD expenses

represented

2.4% and 2.8% of

revenue

for the years ended December

31 2010 and

for 2010 were $0.5 million compared to $0.5 million for

2009 respectively

Interest

income decreased

approximately

$22000 to approximately

December

31 2010 compared to $45000 for the year ended December

$23000 for the year ended
31 2009 Interest

income in both

periods represented

interest

and dividends

earned on cash equivalents

and short-term investments

decrease

in the yield on investment

balances

in 2010

as compared to 2009 caused

the decrease

in interest

income

16

During the year ended December

31 2010 the Company recorded

tax provision

of $1.8 million

representing an effective

tax rate of 41.1% During the year ended December

31 2009 the Company recorded

tax provision

of $1.1 million representing an effective

tax rate of 41.9% We do not expect

significant

change

in our tax rate in the foreseeable future

for the Year Ended December 31 2009 Compared to Results for the Year Ended December 31

Results

2008

Revenue

decreased

$6.0 million or 26% to $17.0 million in 2009 compared to $22.9 million in 2008

This decrease was due in

part

to decreased

testing

volume which fell 26% compared to 2008 Average

revenue

per sample was unchanged

between 2009

and 2008 Revenue

included the recognition

of deferred

revenue

relating

to the sale of PDT-90

products

was $0.1 million for each

of the years ended December

31

2009 and 2008

Gross profit decreased

$3.7 million to $9.6 million in 2009 compared to $13.4 million in 2008 Direct

costs decreased
The gross profit margin fell from 58% in 2008 to 57% in 2009 as revenue

by 23% from 2008 to 2009 mainly due to lower

General and administrative GA expenses were $3.6 million for

labor and associated

direct

cost of materials

declined more than direct

costs

the year ended December

31 2009

compared to $4.5 million for

the year ended December
of revenue GA expenses were 21.2% and

percentage

31 2008 representing
19.7% for the years ended December

decrease of 20% As

31 2009 and

2008 respectively

The decrease

in general and administrative

expenses

in 2009 was due primarily to

decrease

in several categories

lower

legal fees defending

our technology

on behalf of our customers reduced

salaries

and stock compensation

decreased

bad debt expense

and lower consulting fees

Marketing and selling

expenses were $3.0 million for the year

ended December

31 2009 compared to

$3.6 million for

the year ended December

31 2008

decrease

of 19% The variation in marketing

and selling

expenses was primarily due to lower staffing

levels

salary

expense

and reduced

benefit

expense of

approximately

$289000 Total marketing

and selling

expenses

represented

17.5% and 15.9% of

revenue

for

the years

ended December

31 2009 and 2008 respectively

Research and development RD expenses

represented

2.8% and 2.1% of revenue

for the years ended December

31 2009 and

for 2009 were $0.5 million compared to $0.5 million for

2008 RD expenses
2008 respectively

Interest

income decreased

approximately

$263000

to approximately

December

31 2009 compared to $308000 for the year ended December

$45000 for the year ended
31 2008 Interest

income in both

periods represented

interest

and dividends

earned

on cash equivalents

and short-term investments

Lower

average

investment

balances

along with

decrease

in the yield on investment

balances

in 2009

as compared

to 2008 caused

the decrease

in interest

income

During the year ended December

31 2009 the Company recorded

tax provision

of $1.1 million

representing an effective

tax rate of 41.9% During the year ended December
tax rate of 40.8%

of $2.0 million representing an effective

tax provision

31 2008 the Company recorded

Liquidity

and Capital Resources

At December

31 2010 the Company had $5.7 million of cash cash equivalents and short
31 2009 The Companys operating activities

compared to $5.8 million at December

term

generated

investments

net cash of $3.3 million in 2010 $2.4 million in 2009 and $3.7 million in 2008 Investing

activities

used

$1.9 million in 2010 used

$1.1 million in 2009

and generated

$3.5 million in 2008 Financing

activities

used

$2.6 million in 2010 $3.1 million in 2009

and $6.7 million in 2008

Operating

cash

flow of $3.3 million in 2010 primarily reflected

net income of $2.6 million adjusted for

depreciation

and amortization

of $0.3 million stock compensation

expense

of $0.4 million an increase in

prepaid expenses

and accounts

receivable of $0.9 million and an increase in accounts

payable

of $0.5 million

and an increase in accrued

expenses

of $0.2 million Operating

cash

flow of $2.4 million in 2009 primarily

reflected

net income of $1.5 million adjusted for depreciation and amortization

of $0.3 million stock

compensation

expense

of $0.4 million

decrease

in prepaid expenses

and accounts

receivable

of $0.8 million

and accounts

payable

of $0.5 million and

decrease

in accrued

expenses

of $0.2 million Operating

cash

flow

17

of $3.7 million in 2008 primarily reflected

net

income of $3.0 million adjusted for depreciation

and

amortization

of $0.3 million stock

compensation expense

of $0.6 million offset by an increase in accrued

expenses

of $0.4 million and an increase in prepaid expenses
of $0.3 million We expect operating cash

flow to

increase as our projected sales

increase

Investing cash

flow principally reflected

the purchase

of short-term investments

and capital

expenditures

During 2010 the Company invested in short-term investments

of $1.0 million During 2009 the Company

invested in short-term investments

of $1.0 million while in 2008 the Company redeemed at par

investments

of

$3.9 million Capital expenditures were $0.8 million $0.04 million and $0.3 million in 2010 2009 and 2008

respectively
equipment We expect

The expenditures

related principally to new equipment

laboratory
to increase from the current year as additional

including

and computer

software and

capital

expenditures

equipment

is purchased

primarily for our laboratory

During 2010 the Company repurchased

17219

shares of common stock

for

822 shares for

In 2009 the Company repurchased
treasury The Company has authorized 750000 shares for repurchase

treasury

since

June

of 1998

of which 250000 shares of common stock were authorized in March

of 2009 for

repurchase

Since

1998

total of 547899 shares have been repurchased

The Company also distributed $2.5 million

$3.0 million and $6.1 million of which $2.6 million was

special

dividend of cash dividends

to its

shareholders in 2010 2009 and 2008 respectively

At December

31 2010 the Companys principal sources of

liquidity

included

approximately

$5.7 million

of cash cash

equivalents

and short-term investments

Management

currently believes that

such

funds together

with future operating profits should

be adequate

to fund anticipated working capital

requirements

and capital

expenditures

in the near

term Depending upon the Companys results

of operations

its future capital

needs

and available marketing

opportunities

the Company may use various financing

sources

to raise additional

funds Such

sources

could

include joint

ventures

issuance

of common stock or debt

financing

although

there

is no assurance

that

such

financings will be available to the Company on terms it deems

acceptable

if at all

At December

31 2010 the Company had no long-term debt

The Company has paid dividends

over

the past

fifty-eight

quarters

It most recently declared

dividend

in March

2011 which was paid in March

2011

and amounted to $625442 The Companys current

intention is

to continue

to declare dividends

to the extent

funds are available and not required for operating purposes

or

capital

and only then upon approval
in the future the Company will declare dividends

requirements

by the Board of Directors

There can be no assurance

that

Contractual

obligations

as of December

31 2010 were as follows

Contractual

Obligation

Operating

leases

Purchase

commitment

Total

Purchase Commitment

Payments

Due by Period

Less Than

Year

Years

35

Years

Greater

Than

Years

Amounts

in Thousands

$738

$54

546

569

$1155

$738

$54

Total

$1338

569

$1907

The Company has

supply agreement with

vendor which requires the Company to purchase

isotopes

used

in its drug

testing

procedures

from this sole supplier at prices based

upon prior year purchase

levels

Purchases

amounted to $432000 $584000 and $606000

in 2010 2009 and 2008 respectively

The Company

expects

to purchase

$569000

in 2011

In exchange for exclusivity the supplier has provided

the Company

with the right

to purchase

the isotope technology

at fair market

value

under

certain

conditions

including

the

failure to meet

the Companys purchase

commitments

This agreement

does

not

include

fixed termination

date however

it is cancelable

upon mutual

agreement by both parties

or after six months termination

notice

by the Company of

its intent

to use

different

technology

in connection

with its drug testing

procedures

18

Critical Accounting

Policies

The Companys significant

accounting

policies are described

in Note

to the financial

statements

included in Item

of this Form 10-K Management

believes the most critical accounting

policies are as

follows

Revenue

Recognition

The Company is in the business

of performing

drug

testing

and reporting the results

thereof

The

Companys drug

testing

services include training

for collection

of samples

and storage of positive samples

for

its customers

for an agreed-upon

fee

per

unit tested of samples The revenues

are recognized

when the

predominant deliverable

drug

testing is provided

and reported to the customer

The Company recognizes

Revenue Recognition

Standards Codification ASC 605
In accordance with ASC 605 the Company considers testing training and storage

with Accounting

in accordance

revenue

elements

as one unit of accounting

for

revenue

recognition

minimis and do not have stand-alone value

to the customer

purposes
The Company recognizes

as

the training and storage costs are de

revenue

as

the service

is performed and reported to the customer

since the predominant deliverable

in each

arrangement

is the

testing

of

the units

The Company also provides expert

testimony when and if

necessary

to support

the results

of the tests

which is generally billed separately and recognized

as the services are provided

Deferred

revenue

represents payments received

in advance

of

the performance

of drug

testing

procedures

generally in relation

to the personal drug testing

kits PDT-90 Deferred

revenue

is recognized

as revenue when

the underlying

test

results

are delivered With respect

to

portion of

these transactions

there may be instances

where the customer ultimately does not require performance

Revenue

is then recognized

when the Company

can

reasonably

reliably

and objectively

determine

that

it is remote that performance

will be required for an

estimable portion of

transactions

The Company recorded approximately

$24000 $128000 and $90000

of

revenue

in the results

of operations for

the years ended December

31 2010 2009 and 2008 respectively

related to test kits that were sold for which the Companys obligations

to provide service were deemed

remote

Estimates

The preparation of

financial

statements

in conformity with accounting

principles generally

accepted

in the

United

States requires management

to make estimates

including

bad debts and income tax valuation

and

assumptions

that affect

the reported amounts of assets and liabilities and disclosure of contingent

assets

and

liabilities at

the date of

the financial

statements

and the reported amounts of revenues

and expenses

during the

reporting

period Actual

results

could differ

from those estimates

Allowance

for Doubtful Accounts

The

allowance

for doubtful

accounts

is based

on managements

assessment

of

the ability

to collect

amounts owed to it by its customers Management
and uses

based

methodology

on calculating the allowance

reviews

its accounts

receivable aging

for doubtful

accounts

using

combination

of

factors including

the age

of

the receivable along with managements

judgment

to

identify

accounts

that may not be collectible The

Company routinely assesses the financial

strength of

its customers

and as

consequence

believes that

its

accounts

receivable credit

risk exposure

is limited The Company maintains an allowance

for potential credit

losses but historically

has not experienced

any significant

losses related to individual customers

or groups of

customers

in any particular industry or geographic

area Bad debt

expense

has been within managements

expectations

Income

Taxes

The Company

accounts

for income taxes using the liability method which requires the Company to

recognize

current

tax liability or asset

for current

taxes payable

or refundable and

deferred tax liability or

asset for the estimated future tax effects of

temporary

differences between the financial

statement

and tax

reporting bases of assets

and liabilities to the extent

that

they are realizable Deferred

tax expense benefit

results

from the net change

in deferred tax assets

and liabilities during the year

deferred tax valuation

allowance

is required if it is more likely

than not

that all or

portion of the recorded

deferred tax assets will

not be realized

19

The Company had net deferred tax assets

in the amount of $240000

at December

31 2010 which the

Company believes are fully realizable based

upon expected

future taxable income which the Companys

believes is reasonably

attainable

in light of previous operating results

during the past three years

The Company operates within multiple taxing jurisdictions

and could

be subject

to audit

in these

jurisdictions These audits may involve complex
resolve The Company has provided

issues which may require an extended

period of

time to

for its estimated taxes payable

in the accompanying

financial

statements

Interest

and penalties related to income tax matters are recognized

as

general and administrative

expense

The Company did not have
as of December

any unrecognized
31 2010 or 2009 The Company does

tax benefits

and did not have

any interest

or penalties accrued

not expect

the unrecognized

tax benefits to change

significantly

over

the next

twelve months

The above

listing is not

intended

to be

comprehensive list of all of

the Companys accounting

policies

In many cases the accounting

treatment of

particular

transaction is

specifically

dictated by accounting

principles generally

accepted

in the United

States with no need for managements

judgment

in their

application

There are also areas in which managements

judgment

in selecting any available alternative

would

not produce

materially different

result

Recent Accounting

Pronouncements

In April 2010 the FASB issued Accounting

Standards Update or ASU No 2010-17 Revenue

Recognition
ASU 2010-17 allows the milestone method as

Milestone Method

Topic 605 Milestone Method

an acceptable

revenue

of Revenue Recognition or ASU 2010-17
recognition methodology when an

arrangement

includes substantive milestones ASU 2010-17 provides

definition

of substantive milestone and

should

be applied regardless of whether

the arrangement

includes single or multiple deliverables

or units of

ASU 2010-17 is limited to transactions involving milestones relating

to research

and development

accounting
deliverables ASU 2010-17 also includes enhanced

disclosure requirements

about

each arrangement

individual

milestones and related contingent

consideration

information

about substantive milestones and factors

considered

in the determination

ASU 2010-17 is effective

on

prospective basis for milestones achieved

in

fiscal years

and interim periods within those years beginning

on or after

June 15 2010 with early adoption

permitted

The adoption

of

this standard

is not expected

to have

material

impact

on the Companys financial

position

results of operations or cash

flows

In October 2009 the FASB issued ASU No 2009-14

Software

Topic 985 Certain Revenue
of the FASB EITF or ASU 2009-14

Arrangements
ASU 2009-14 changes

That

Include Software

Elements

consensus

the accounting model

for

revenue

arrangements

that

software elements The amendments

of this update provide additional

guidance

include tangible products
on how to determine

and

which

software

if any relating

to the tangible product

also would be excluded

from the scope

of the software

revenue

recognition guidance

The amendments

in this update also provide guidance

on how

vendor should

allocate

arrangement

consideration

to deliverables

in an arrangement

that

includes both tangible products

and

software

as well

as arrangements

that have deliverables

both included and excluded

from the

scope

of

software revenue

recognition

guidance This standard

is effective

prospectively

for revenue

arrangements

entered

into or materially modified in fiscal years beginning

on or after

June 15 2010 The adoption

of this

standard

is not expected

to have

material

impact

on the Companys financial

position

results

of operations

or cash

flows

In October

2009 the FASB issued ASU No 2009-13 Revenue Recognition

Topic 605

Multiple-Deliverable
ASU 2009-13 will separate multiple-deliverable

Revenue Arrangements

consensus of the FASB EITF or ASU 2009-13

revenue arrangements This update establishes

selling

price

hierarchy

for determining

the selling

price of

deliverable

The amendments

of this update will

replace the

term fair value in the revenue

allocation guidance

with selling price to clarify

that

the allocation

of

revenue

is based

on entity-specific

assumptions

rather

than assumptions

of

marketplace

participant

The

amendments

of this update will eliminate

the residual method of allocation and require that arrangement

consideration

be allocated at the inception of

the arrangement

to all deliverables

using the relative

selling

price method

The amendments

in this update will

require that

vendor determine

its best estimated selling

price in manner consistent with that used

to determine

the price to sell

the deliverable

on

standalone

basis

This standard

is effective

prospectively

for

revenue

arrangements

entered

into or materially modified in fiscal

20

years beginning

on or after

June 15 2010 The adoption

of

this standard

is not expected

to have

material

impact

on the Companys financial

position

results of operations or cash

flows

Effective

January

Disclosures Topic 820 Improving

2010 the Company adopted ASU No 2010-06 Fair Value Measurements
or ASU 20 10-06

about Fair Value Measurements

Disclosures

and

reporting

entity

should

provide additional disclosures about

the different

classes of assets

and liabilities measured at

fair

value the valuation techniques

and inputs used the activity

in Level

fair value measurements

and the

transfers

between Levels

and

fair value measurements

The adoption

of the additional disclosures for

Level

and Level

fair value measurements did not have an impact

on our financial

position

results

of

operations or cash

flows The disclosures regarding Level

fair value measurements

do not become

effective

until January

2011

and the adoption

is not expected

to have

material

impact

on the Companys financial

position

results

of operations

or cash

flows

Item 7A Quantitative

and Qualitative

Disclosures About Market Risk

Not Required

21

Item

Financial Statements and Supplementary

Data

Financial Statements

Report

of

Independent

Registered

Public Accounting Firm

Balance

Sheets

as of December

31 2010

and 2009

Statements

of

Income for

the Years Ended December

31 2010 2009 and 2008

Statements

of Shareholders

Equity for the Years Ended December

31 2010 2009 and

2008

Statements

of Cash Flows for the Years Ended December

31 2010 2009 and 2008

Notes

to Financial Statements

Not Covered by Above Report

Unaudited Supplementary Quarterly Financial

Information

Page

23

24

25

26

27

28

38

22

REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Board of Directors

and

Shareholders

of Psychemedics Corporation

Acton Massachusetts

We have audited the accompanying

balance

sheets of Psychemedics Corporation

the Company

as of

December

31 2010

and 2009

and the related

statements

of

income

shareholders

equity and cash

flows for

each of

the three

years

in the period ended December

31 2010 These

financial

statements

are the

responsibility of

the Companys management

Our responsibility is to express

an opinion on these financial

statements

based

on our audits

We conducted

our audits in accordance

with the standards

of

the Public Company Accounting Oversight

Board United States Those

standards

require that we plan and perform the audit

to obtain reasonable

assurance

about whether

the financial

statements

are free of material misstatement

The Company

is not

required to have nor were we engaged

to perform an audit of

its internal

control

over

financial

reporting Our

audit

includes consideration

of

internal

control

over

financial

reporting

as

basis

for designing audit

procedures

that are appropriate in the circumstances

but not

for

the purpose

of expressing an opinion on the

effectiveness of the Companys internal

control over

financial

reporting Accordingly we express

no such

opinion An audit also includes examining on

test basis evidence

supporting the amounts and disclosures in

the financial

statements

assessing

the accounting

principles used

management as well

as evaluating the overall

financial

statement

and significant
presentation We believe that our audits

estimates made by

provide

reasonable

basis for our opinion

In our opinion the financial

statements

referred to above present

fairly in all material

respects the

financial

position of the Company at December

31 2010

and 2009

and the results of

its operations and its

cash

flows for each

of

the three years in the period ended December

31 2010 in conformity with accounting

principles generally

accepted

in the United

States of America

Is BDO USA LLP

Boston Massachusetts

March

25 2011

23

PSYCHEMEDICS CORPORATION

BALANCE SHEETS

ASSETS

Current assets

Cash and cash equivalents

Short-term investments

Accounts

receivable

net of allowance

of $119295

in 2010 and

$134282

in 2009

Prepaid

expenses

and other current

assets

Deferred

tax assets

Total current

assets

Property and equipment

net

Computer software

Office furniture

and equipment

Laboratory

equipment

Leasehold

improvements

Less

accumulated

depreciation

and amortization

Deferred

tax assets net of current portion

Other

assets

Total assets

LIABILITIES AND SHAREHOLDERS

EQUITY

Current

liabilities

Accounts

payable

Accrued

expenses

Deferred

revenue

Total current

liabilities

Commitments

and contingencies

Note 10

Shareholders

equity

December

31

2010

2009

3720488

2018452

4840367

1006436

3905821

3016084

700822

239831

663433

253221

10585414

9779541

1290255

2032406

7493190

1205840

1967701

6830750

915015

908615

11730866

10912906

10663996

10381599

1066870

114037

531307

204764

86814

11766321

10602426

699833

180784

1302370

1090898

16605

36360

2018808

1308042

Preferred stock

$0.005 par value 872521

shares authorized

no shares

issued or outstanding

Common stock

$0.005

par value 50000000 shares authorized

5877358 shares issued in 2010

and 5861872 shares issued in 2009

29387

29309

Additional

paid-in capital

27764992

27419359

Treasury

stock

at cost 665345 shares in 2010 and 664523 shares in

2009

Accumulated

deficit

Total shareholders

equity

Total

liabilities and shareholders

equity

10059398

10053364

7987468

9747513

8100920

9294384

11766321

10602426

The accompanying

notes are an integral part of these financial statements

24

PSYCHEMEDICS CORPORATION

STATEMENTS

OF INCOME

Revenues

Cost of

revenues

Gross profit

Operating

expenses

General

and administrative

Marketing and selling

Research

and development

Total operating expenses

Income from operations

Interest

income

Income before taxes

Provision

for income taxes

Net

income

Basic net income per share

Diluted income per share

Dividends

declared

per share

Special dividends

declared

per share

Year Ended December

31

2010

2009

2008

$20108862

$16954994

$22948604

8067229

7345016

9598515

12041633

9609978

13350089

4195998

2949739

3596774

2961477

481433

467435

7627170

7025686

4414463

2584292

4520074

3648584

474622

8643280

4706809

23091

4437554

1823834

2613720

0.50

0.50

0.48

0.00

45320

308034

2629612

1102317

1527295

5014843

2046054

2968789

0.29

0.29

0.53

0.00

0.57

0.57

0.66

0.50

Weighted average

common shares outstanding

basic

5207244

5193329

5219141

Weighted average

common shares outstanding

diluted

5226454

5204767

5245713

The accompanying

notes are an integral

part of

these financial statements

25

PSYCHEMEDICS CORPORATION

STATEMENTS

OF SHAREHOLDERS

EQUITY

Treasury

Stock

Common Stock

Shares

5811982

17931

13155

$O.005
par Value

$29060

90

66

BALANCE December 31 2007

Exercise

of stock

options

Shares issued

vested

Stock compensation

expense

Acquisition

of treasury

stock

Cash

dividends

declared

$1.16

per share

Net

income

Paid-In

Capital

Shares

Cost

Deficit

Total

Accumulated

$26539764

586197

9163624

$3527269

$13877931

199114

66

379931

61107

810333

199204

379931

810333

6055634

6055634

2968789

6614114

2968789

10559888

BALANCE December

31 2008

5843068

29216

27118743

647304

9973957

Shares

issued

vested

18804

93

Tax withholding related to

vested

shares

from employee

stock

pians

Stock compensation

expense

Change

in excess

tax benefit on

equity

awards

Acquisition

of

treasury

stock

Cash

dividends

declared

$0.53 per share

Net

income

93

39381

394498

54408

17219

79407

___________

3014101

1527295

BALANCE December

31 2009

5861872

29309

27419359

664523

10053364

8100920

Shares issued

vested

15486

78

Tax withholding related to

vested

shares

from employee

stock

plans

Stock compensation

expense

Acquisition

of

treasury

stock

Cash

dividends

declared

$0.48 per share

Net

income

78

49261

394972

822

6034

2500268

2613720

BALANCE December

31 2010

5877358

$29387

$27764992

665345

$10059398

$7987468

39381

394498

54408

79407

3014101

1527295

9294384

49261

394972

6034

2500268

2613720

9747513

The accompanying

notes are an integral

part of

these financial statements

26

PSYCHEMEDICS CORPORATION

STATEMENTS

OF CASH FLOWS

Cash flows from operating activities

Net

income

Adjustments to reconcile net

income to net cash

provided

by operating activities

Depreciation

and amortization

Deferred

income taxes

Change

in excess

tax benefit on equity awards

Stock compensation

expense

Changes

in operating assets

and liabilities

Accounts

receivable

Prepaid

expenses

and other current assets

Accounts

payable

Accrued expenses

Deferred

revenue

Net cash

provided

by operating activities

Cash flows from investing activities

Maturities

of short-term investments

Purchases

of short-term investments

Increase

in other

long-term assets

Purchases

of property

and equipment

Net cash

provided

by used in investing activities

Cash flows from financing

activities

Dividends

paid

Proceeds

from employee stock plans and stock option

exercises

net of

tax withholding

Acquisition

of

treasury stock

Tax benefit associated with exercise of options

Net cash

used

in financing activities

Net

increase decrease

in cash

and cash equivalents

Cash and cash equivalents

beginning

of year

Cash and cash equivalents

end of year

Supplemental

disclosures of cash

flow information

Year Ended December

31

2010

2009

2008

2613720

1527295

2968789

284911

218154

394972

889737

37389

519049

211472

19755

336795

130434

54408

394498

382371

442453

464110

178026

117720

331393

72399

379931

156887

606967

156254

317682

88875

3295397

__________

2399582

3687493

1012016

1006436

29737

817960

14582

35427

1859713

__________

1056445

__________

3875000

17811

344534

3512655

2500268

3014101

6055634

49261
6034

39381

79407

189891

810333

9313

2555563

3132889

6666763

1119879

1789752

4840367
_________
3720488

6630119
_________
4840367

533385

6096734

6630119

Cash paid for

income taxes

2009694

112449

2553537

Non-cash investing and financing activities

Issuance

of restricted

stock awards

78

93

66

The accompanying

notes are an integral part of these financial statements

27

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS
December 31 2010

Nature of Business

and Basis of Presentation

Psychemedics Corporation

is the worlds largest

provider of hair testing

for drugs of abuse utilizing

patented hair analysis method involving

radioimmunoassay

technology

and confirmation

by mass spectrometry

to analyze

human hair

to detect abused

substances

The Companys customers

include Fortune

500 companies

as well as small

to mid-size corporations

schools

and governmental

entities

located primarily in the

United

States

Summary of Significant

Accounting

Policies

Risks and Uncertainties

The Company is subject

to

number of risks and uncertainties similar to those of other companies

such

as those associated with the continued

expansion

of the Companys sales

and marketing

network

development

of markets

for new products

and services offered by the Company

the economic health of principal customers

of

the Company

financial

and operational

risks

associated with possible expansion

of testing

facilities

used

by

the Company

government

regulation including but not

limited to Food

and Drug Administration

regulations

competition

and general economic

conditions

Estimates

The preparation

of financial

statements

in conformity with accounting

principles generally

accepted

in the

United

States requires management

to make estimates

including

those related

to bad debts and income tax

valuation

and assumptions

that affect

the reported amounts of assets

and liabilities and disclosure

of

contingent

assets

and liabilities at

the date of

the financial

statements

and the reported amounts of revenues

and expenses

during the reporting period Actual

results

could differ

from those estimates Changes

in

estimates are recorded

in the period in which they become

known

Cash Equivalents

and Short-Term Investments

All highly

liquid investments

with original maturities of 90 days or less are considered

cash equivalents

These consist of cash

savings U.S government

Certificates

of Deposit CDs at December

31 2010

U.S federal government
$0.6 million was in U.S federal government-backed money-market

issues the account

backed

itself

reserve money market accounts

and government
and 2009 While the money market account
is not federally insured As of December

insured

contains

31 2010

accounts

and $2.0 million was in CDs

with maturities under

90 days

all of which are classified

as cash

and cash equivalents

There was also $2.0 million of CDs with maturities within

14 weeks

that are classified

as short-term

investments

The Company accounts

for

investment

securities

in accordance

with Accounting

Standards

Codification ASC 320 Under ASC 320 investments

that

the Company has positive intent

and ability

to hold

are classified

to maturity
market value The Company intends to hold all CDs to maturity All short-term investments
31 2010 The Company does

held-to-maturity at December

not use derivative

as held-to-maturity and are reported at amortized cost which approximates

instruments

financial

fair

for

were classified

as

speculative or trading purposes

28

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS
December 31 2010

Summary of Significant

Accounting

Policies

continued

During the first quarter of 2008 the Company

adopted ASC 820 Fair Value Measurements

and

Disclosures

which defines fair value establishes guidelines

regarding fair value measurements Fair value

and expands disclosures
is defined under ASC 820 as the exchange price that would be

for measuring

fair value

received

for an asset or paid to transfer

liability an exit price
the asset or liability in an orderly transaction between market

for

in the principal or most advantageous market

participants

on the measurement date

Valuation techniques

used

to measure fair value

under ASC 820 must maximize the use of observable

inputs

and minimize the use of unobservable

inputs

The standard

describes

fair value hierarchy

based

on three

levels

of

inputs of which the

first

two are considered

observable

and the last unobservable

that may be used

to measure fair value which are the following

Level

Level

Quoted prices in active markets

for

identical

assets or liabilities

Inputs other than Level

that are observable

either

directly

or indirectly such

as quoted

prices for similar assets

or liabilities quoted prices in markets

that are not active

or other

inputs that are observable

or can be corroborated by observable market data for substantially

the full

term of the assets or liabilities

Level

Unobservable

inputs that are supported

by little or no market activity

and that are significant

to the fair value

financial

instruments

level within the fair value hierarchy

is based

on the lowest

level of any input

that

is

significant

to the fair value measurement

In accordance

with ASC 820 the Companys financial

assets

that are measured at

fair value

on

recurring basis as of December

31 2010 are cash cash equivalents and short

term investments

The cash cash

equivalents

and short

term investments

are measured using level

one inputs

Inventory

The Company expenses

consumables such

as chemicals

and antibodies as purchased

The Company

has

supply agreement with

vendor which requires the Company to purchase

isotopes used

in its drug

testing

procedures

from this sole supplier

in exchange for variable annual payments based

upon prior year purchases

Property

and Equipment

Property and equipment are stated

at cost Depreciation

and amortization

are provided

over

the estimated

useful

lives of

the assets using the straight-line

method Repair

and maintenance

costs are expensed as

incurred

The estimated useful

lives of

the assets

are as

follows

Computer

software

Office furniture

and equipment

Laboratory

equipment

Leasehold

improvements

to

to

to

years

years

years

Lesser of term of lease or estimated useful

life

The Company recorded

depreciation

and amortization

related

to property and equipment of $282397

$333844 and $331393

in 2010 2009

and 2008

respectively

Other Assets

Other

assets primarily consist of capitalized

legal costs relating

to patent applications

The Company

amortizes

these costs over

10 years from the date of grant of the applicable patent As of December

31 2010

and 2009 the Company had capitalized legal

costs relating

to an outstanding patent application of $26938

The amount of amortization

related

to patent applications

is expected

to remain

and $13064 respectively
below $10000 per year for

the next

years

29

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS
December 31 2010

Summary of Significant

Accounting

Policies

continued

Revenue Recognition

The Company is in the business

of performing

drug testing

services and reporting the results

thereof

The

Companys drug testing

services include training

for collection of samples

and storage of positive samples

for

its customers

for an agreed-upon

fee per unit

tested

of samples The revenues

are recognized

when

the

predominant

deliverable

drug

testing is provided

and reported to the customer

The Company recognizes

revenue

ASC 605 the Company

considers testing training

under ASC 605 Revenue Recognition
and storage elements

In accordance

with

as one unit of accounting

for

revenue

recognition purposes

as

the training

and storage costs

are de minimis and do not have stand-alone value

to

the customer The Company recognizes

revenue

as the service is performed and reported to the customer

since the predominant deliverable

in each

arrangement

is the

testing

of

the units

The Company also provides expert

testimony when and

if necessary

to support

the results

of the tests

which is generally billed separately and recognized

as

the services are provided

Deferred

revenue

represents payments received

in advance

of

the performance

of drug

testing procedures

generally in relation

to the personal drug testing

kits PDT-90 Deferred

revenue

is recognized

as

revenue when

the underlying

test

results

are delivered With respect

to

portion of

these transactions

where the customer

ultimately does

not require performance

Revenue

is then recognized

there may be instances
when the Company

can

reasonably

reliably

and objectively

determine

that

it is remote that performance

will be required for an

estimable portion of transactions

The Company recorded

$24145 $127809 and $89714 of

revenue

in the

results of operations for

the years ended December

31 2010 2009 and 2008 related

to test kits that were

sold for which the At December

31 2010 and 2009 the Company had deferred revenue

of approximately

$17000

and $36000 respectively

reflecting

sales of

its personal drug

testing

service for which the

performance

of the related test had not yet occurred

and future

obligations were not deemed

remote

Companys

Research and Development

Expenses

The Company charges all research

and development

expenses

to operations as incurred

Income Taxes

The Company accounts

for

income taxes using the liability method pursuant

to FASB ASC 740 Income

Taxes Under

this method the Company recognizes

deferred tax assets

and liabilities for

the expected

tax

consequences

of temporary

differences between the tax bases of assets

and liabilities and their

reported

amounts using enacted

tax rates

in effect

for

the year the differences are expected

to reverse The Company

evaluates

uncertain tax positions annually and considers whether

the amounts recorded

for

income taxes are

adequate

to address

the Companys tax risk profile The Company

analyzes

the potential

tax liabilities of

specific

transactions and tax positions based

on managements

judgment

as

to the expected

outcome

Concentration

of Credit Risk and Off-Balance

Sheet Risk

The Company has no significant

off-balance-sheet

risk such

as foreign exchange contracts

option

contracts or other

foreign hedging

arrangements Financial

instruments that potentially subject

the Company

to concentrations

of credit

risk are principally cash

and cash equivalents

short-term investments

and accounts

receivable

institutions

The Company places
These include money market accounts

its cash

and cash equivalents

and short-term investments

in highly

rated

holding U.S federal government

reserve securities While

the underlying

securities

are federally issued the account

itself is not

insured Concentration

of credit

risk

with respect

to accounts

receivable is limited to certain

customers

sales To reduce

risk the Company routinely assesses the financial

to whom the Company makes
strength of its customers

and as

substantial

consequence believes that

its accounts

receivable credit

risk exposure

is limited The Company maintains an

30

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS
December 31 2010

Summary of Significant

Accounting

Policies

continued

allowance

for potential

credit

losses but historically

has not experienced

any significant

losses related

to

individual customers

or groups

of customers

in any particular

industry or geographic

area The Company does

not require collateral

Comprehensive

Income

The Companys comprehensive

income is the same as its reported net income for the years ended

December

31 2010 2009 and 2008

Stock-Based Compensation

The Company accounts

for equity awards in accordance

with ASC 718 Compensation

Stock

FASB ASC 718 requires employee equity awards to be accounted

Compensation
method Accordingly share-based
award It also requires the measurement of compensation cost at fair value

is measured at

compensation

the grant date based

for under

the fair value

on the fair value of

the

on the date of grant and

recognition

of compensation

expense over

the service period for awards expected

to vest The Company uses

the straight-line

attribution

method to recognize

share-based

compensation

over

the service period of

the

award which is generally equal

to the vesting period

Under ASC 718 the Company recorded

$394972 $394498 and $379931

of stock compensation

expense

in the accompanying

statements

of income for the years ended December

31 2010 2009

and 2008

respectively

See Note

for additional

information

relating

to the Companys stock plans

Basic and Diluted Net

Income per Share

Basic net

income per share is computed by dividing

net income available to common shareholders by the

weighted

average number of common shares outstanding during the period Diluted net

income per

share is

computed by dividing

net income by the weighted

average number of conmion shares and dilutive

common

stock equivalents outstanding

during the period The number of dilutive

common stock equivalents

outstanding during the period has been determined

in accordance

with the treasury-stock method Common

equivalent

shares consist of common stock

issuable upon

the exercise of outstanding options and the unvested

portion of stock unit awards SUAs

Basic

and diluted weighted

average

common shares outstanding are as

follows

Weighted average

common shares outstanding

5207244

5193329

5219141

Dilutive common equivalent

shares

19210

11438

26572

Weighted average

common shares outstanding

assuming dilution

5226454

5204767

5245713

2010

2009

2008

For the years ending December

31 2010 2009 and 2008 options to purchase

298390 361382 and

331292 common shares

respectively were outstanding but not included in the dilutive

common equivalent

share calculation

as

their effect would have been anti-dilutive

Financial

Instruments

Financial

instruments

include cash equivalents

short-term investments

and accounts

receivable/payable

Estimated

fair values of

these financial

instruments approximate

carrying values

due to their short-term nature

Segment

Reporting

The Company manages

its operations as one segment

drug

testing

services As

result

the financial

information

disclosed herein materially represents all of

the financial

information

related to the Companys

principal operating segment Substantially

all of the Companys revenues

and assets

are in the United States

31

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS
December 31 2010

Summary of Significant

Accounting

Policies

continued

Subsequent Events

The Company evaluated

all events

time of

filing with the SEC of the Companys annual
the Company did not have

2010 During this period

and transactions that occurred

after December

31 2010 through
report on Form 10-k for the year ended December
any material

recognizable

subsequent

events

the

31

Recent Accounting

Pronouncements

In April 2010 the FASB issued Accounting

Standards Update or ASU No 2010-17 Revenue

Milestone Method

Recognition
ASU 2010-17 allows the milestone method as an acceptable

revenue
includes substantive milestones ASU 2010-17 provides

Topic 605 Milestone Method

arrangement

of Revenue Recognition or ASU 2010-17
recognition methodology when an

definition

of substantive milestone and

should

be applied regardless of whether

the arrangement

includes single or multiple deliverables

or units of

ASU 2010-17 is limited to transactions involving milestones relating

to research

and development

accounting
deliverables ASU 2010-17 also includes enhanced

disclosure requirements

about

each

arrangement

individual

milestones and related contingent

consideration

information

about substantive milestones and factors

considered

in the determination

ASU 2010-17 is effective

on

prospective

basis for milestones achieved

in

fiscal years and interim periods within those years beginning

on or after

June 15 2010 with early adoption

permitted

The adoption

of

this standard

is not expected

to have

material

impact

on the Companys financial

position

results of operations or cash

flows

In October 2009 the FASB issued ASU No 2009-14

Software

Topic 985 Certain Revenue
of the FASB EITF or ASU 2009-14

Arrangements
ASU 2009-14 changes

That

Include Software

Elements

consensus

the accounting model

for revenue

arrangements

that

software elements The amendments

of this update provide additional

guidance

include tangible products
on how to determine

and

which

software

if any relating

to the tangible product

also would be excluded

from the scope

of the software

revenue

recognition

guidance The amendments

in this update also provide guidance

on how

vendor should

allocate

arrangement

consideration

to deliverables

in an arrangement

that

includes both tangible products

and

software

as well

as arrangements

that have deliverables

both included and excluded

from the scope

of

software revenue

recognition

guidance This standard

is effective

prospectively

for

revenue

arrangements

entered

into or materially modified in fiscal years beginning

on or after

June 15 2010 The adoption

of

this

standard

is not expected

to have

material

impact

on the Companys financial

position

results of operations

or cash

flows

In October 2009 the FASB issued ASU No 2009-13 Revenue Recognition

Topic 605

Multiple-Deliverable
ASU 2009-13 will separate multiple-deliverable

Revenue Arrangements

consensus

of the FASB EITF or ASU 2009-13

revenue arrangements This update establishes

selling

price

hierarchy

for determining

the selling

price of

deliverable

The amendments

of this update will

replace the

term fair value in the revenue

allocation

guidance with selling price to clarify

that

the allocation

of

revenue

is based

on entity-specific

assumptions

rather

than assumptions

of

marketplace

participant

The

amendments

of this update will eliminate the residual method of allocation and require that arrangement

consideration

be allocated at

the inception

of

the arrangement

to all deliverables

using the relative

selling

price method

The amendments

in this update will

require that

vendor determine

its best estimated selling

price in manner consistent with that used

to determine

the price to sell

the deliverable

on

standalone

basis

This standard

is effective

prospectively

for

revenue

arrangements

entered

into or materially modified in fiscal

years beginning

on or after

June 15 2010 The adoption

of

this standard

is not expected

to have

material

impact

on the Companys financial

position

results of operations or cash

flows

Effective January

Disclosures Topic 820 Improving

2010 the Company adopted ASU No 2010-06 Fair Value Measurements
or ASU 2010-06

about Fair Value Measurements

Disclosures

and

reporting

entity

should

provide additional disclosures about

the different

classes of assets

and liabilities measured at fair

32

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS

December 31 2010

Summary of Significant

Accounting

Policies

continued

value the valuation techniques

and inputs used the activity

in Level

fair value measurements

and the

transfers

between Levels

and

fair value measurements

The adoption

of the additional disclosures for

Level

and Level

fair value measurements did not have

an impact

on our

financial

position

results

of

operations or cash

flows The disclosures regarding Level

fair value measurements do not become

effective

until

January

2011

and the adoption

is not expected

to have

material

impact

on the Companys financial

position

results of operations

or cash

flows

Accounts Receivable

The Company maintains an allowance

for uncollectible

accounts

receivable based

on managements

assessment

of the collectability

of

its customer accounts

by reviewing

customer

payment patterns and other

relevant

factors

The Company reviews

the adequacy of the allowance

for uncollectible

accounts

on

quarterly basis and adjusts the balance

as determined

necessary

The following

is

roliforward of the

Companys allowance

for doubtful accounts

Balance

beginning

of period

Provision

for recoveries of doubtful

accounts

Write-offs

Balance

end of period

Accrued Expenses

Accrued expenses

consist of the following

Accrued payroll and employee benefits

Accrued income taxes

Accrued hair collection expense

Accrued audit and tax consulting

Other

accrued

expenses

Income Taxes

The income tax provision

consists of

the following

Current

Federal

State

Deferred

Federal

State

2010

2009

$134282

$246462

10302

25289

89378

22802

$119295

$134282

2010

607248

117727

151817

425578

2009

392558

331831

79480

98481

188548

$1302370

$1090898

2010

2009

2008

$1261670

344010

810538

215753

$1549593

424062

1605680

1026291

1973655

171848

46306

218154

71540

4486

76026

56819

15580

72399

$1823834

$1102317

$2046054

33

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS
December 31 2010

Income Taxes

continued

reconciliation of

the effective

rate with the federal statutory

rate is as

follows

Federal statutory

rate

State income taxes net of

federal benefit

Permanent differences

Stock

based

compensation

Effective

tax rate

2010

2009

2008

34.0%

34.0%

34.0%

5.6

0.2

1.7

5.7

0.4

1.8

5.8

1.0

41.1%

41.9%

40.8%

The components of the net deferred tax assets

included in the accompanying

balance

sheets are as

follows

at December

31

Deferred

tax assets

Deferred

revenue

Stock-based

compensation

Allowance

for doubtful

accounts

Excess of book

over

tax depreciation

and amortization

Accrued expenses

Deferred

tax liabilities

Prepaid

expenses

Excess of

tax over book depreciation

and amortization

2010

2009

6566

146812

47171

133960

334509

17790

76888

94678

14382

136976

53114

204764

66719

475955

17970

17970

$239831

$457985

ASC 740 contains

two-step approach

to recognizing

and measuring uncertain tax positions

tax

contingencies The first step is to evaluate

the tax position for recognition

by determining

if the weight

of

available evidence

indicates it is more likely

than not

that

the position will be sustained on an audit

including

resolution

of related appeals or litigation

processes

if any

The second

step is to measure the tax benefit as the

largest

amount which is more than 50% likely of being

realized upon ultimate

settlement

The Company

considers many factors when evaluating and estimating the Companys tax positions and tax benefits which

may require periodic adjustments

and which may not accurately forecast actual outcomes

The Company

adopted

these provisions

effective

January

2007 without material effect

in the financial

statements

The Company

operates within multiple taxing jurisdictions

and could

be subject

to audit

in these

jurisdictions These audits may involve complex

issues which may require an extended

period of

time to

resolve

The Company has provided

for

its estimated taxes payable

in the accompanying

financial

statements

Interest

and penalties related

to income tax matters are recognized

as

general and administrative

expense

The Company did not have

any unrecognized

tax benefits and did not have

any interest

or penalties accrued

as of December

31 2010

and 2009 The tax years ended December

31 2007 through

December

31 2010

remain subject

to examination

by all major taxing authorities

Preferred Stock

The Board of Directors

has the authority to designate

authorized preferred shares in one or more series

and to fix the relative

rights

and preferences

without

vote or action by the stockholders

The Board of

Directors

has no present plans to designate

or issue any shares of preferred stock

34

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS

December 31 2010

Stock-Based Awards

In 2006 the Company adopted

new stock-based

plan the 2006 Equity Incentive Plan for officers

directors employees and consultants

The

2006 Equity Incentive Plan provides for grants of options with

terms of up to ten years grants of

restricted

stock or stock unit awards SUAs issuances

of stock

bonuses

or

grants other stock-based

awards

covering

up to 250000 shares of common stock As of December

31 2010

84450 shares remained available for future grant under

the 2006 Equity Incentive Plan

The fair value of the SUAs was determined

by the closing price on the date of grant The SUAs vest

over

period of two to four years and are convertible

into an equivalent number of shares of

the Companys

common stock provided

that

the employee receiving

the award remains

continuously

employed throughout

the

vesting period The Company records compensation
the vesting term of the SUA Employees are issued shares upon vesting

expense

related

net of tax withholdings

to the SUAs on

straight-line

basis over

The Company granted

34000 SUAs to certain members

of management

and its directors

on May 10

2007 The fair value of the SUAs was $18.41

per share which was the closing price of

the Companys stock

on May 10 2007 The SUAs vest over
number of shares of

the Companys common stock provided

that

the awardee remains

continuously

employed

period of

two to four years and are convertible

into an equivalent

throughout

the vesting periods Of these 34000 units 1500 were cancelled

upon termination

of an employee

in 2010 In 2008 2009 and 2010 10000 10000 and 7000 units

vested

and were issued net of

tax

withholdings

respectively

In 2008 the Company granted 32600 SUAs on May 15 1000 SUAs on October

14 and 800 SUAs on

November

The fair values of the SUAs were $16.50 $10.67

and $9.30 per share

respectively

which was

the closing price of the Companys stock on those

dates

The SUAs vest over

period of

two to four years

and are convertible

into an equivalent number of shares of the Companys common stock provided

that

the

awardee remains

continuously

employed throughout

the vesting period Of these 34400 units 1200 were

cancelled

upon termination

of an employee in 2008 and 1850 were cancelled

upon termination

of

three

employees in 2010 In 2009 and 2010 9800 and 9350 of these units

vested and were issued net of

tax

withholdings

respectively

In 2010 the Company granted 94000 SUAs on April

which was the closing price of the Companys stock on that date The SUAs vest over

years and are convertible

into an equivalent number of shares of

the awardee remains

continuously

employed throughout

cancelled

upon termination

of

three employees in 2010

The fair value of the SUAs was $7.75 per share
period of two to four

the Companys common stock provided
the vesting period Of these 94000 units 17000 were

that

The Company also

has stock option plans that have expired or been terminated

but shares can be issued

upon exercise of outstanding options that were granted prior to such

expiration or termination

No additional

grants of options or other stock

based

for these plans is included in this footnote

awards may be made under
under

Options

granted

such

expired or terminated plans Activity

the plans consisted of both non-qualified

and incentive stock options and were granted

in each

case at

price that was not

less than the fair market

value of the common stock at

the date of grant These options generally have

lives of

ten years and vest either

immediately

or over periods up to four years

35

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS
December 31 2010

Stock-Based Awards

continued

summary of stock option activity

for the Companys stock option plans is as follows

Outstanding December

31 2007

Granted

Exercised

Terminated

Outstanding December

31 2008

Granted

Exercised

Terminated

Outstanding December

31 2009

Granted

Exercised

Terminated

Outstanding December

31 2010

Weighted

Average

Exercise

Price
per Share

$15.63

Weighted

Average

Remaining

Contractual

Life

Aggregate

Intrinsic
Va1ue

13.93

20.51

15.22

17.75

14.80

Number

of Shares

450034

18139

39785

392110

55189

336921

47550

289371

19.93

$13.96

3.7 years

The aggregate

intrinsic

value

on this table was calculated based

on the amount

if any by which the

closing market value

of the Companys stock on December

31 2010 $8.20 exceeded the exercise price

of the underlying

options multiplied by the number of shares subject

to each

option

The total

intrinsic

value of stock options exercised calculated based

on the amount by which the market value of

the

Companys stock
years 2010 2009

at the time of exercise exceeded the exercise price was $0 $0 and $65060 for
and 2008 respectively

the

All SUAs were issued for $0 per share

summary of activity

for SUAs under

the Companys 2006

Equity Incentive Plan is as follows

Outstanding

Granted

Unvested

December

31 2007

Converted to common stock

Terminated

Outstanding

Granted

Unvested

December

31 2008

Converted to common stock

Terminated

Outstanding

Granted

Unvested

December

31 2009

Converted to common stock

Terminated

Outstanding

Unvested

December

31 2010

Available for grant December

31 2010

Weighted

Average

Remaining

Contractual

Life

Aggregate

Intrinsic

Value2

282975

156022

179801

3.0 years

$776540

Number

of Shares

51550

34400

17150
1200
67600

25000

42600

94000

21550
20350

94700

84450

The aggregate
stock on December

intrinsic

value

on this table was calculated based

on the closing market price of the Companys

31 2010 $8.20 For value

on the grants converted

to common stock the price used

is

the price on the conversion

date

36

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS
December 31 2010

Stock-Based Awards

continued

intrinsic

The aggregate
Companys stock on December
price used is the price on the grant date

value on this table was calculated based on the closing market

price of the

31 2010 $8.20 For value

on the grants converted

to common stock

the

Total stock

based

compensation expense

for 2010 was $394972

Figure includes 6064 shares in 2010 and 6196 shares in 2009 withheld to cover

federal

income taxes

As of December

31 2010

total of 468521

shares of common stock were reserved

for issuance

under

the various stock option and stock-based

plans As of December

31 2010 the unamortized

fair value of

awards relating

to SUAs was $638155

to be amortized over

weighted

average period of approximately

years

Employee Benefit Plan

The Psychemedics Corporation 401k Savings

and Retirement

Plan the 40 1k Plan is

qualified

defined contribution

plan in accordance

with Section

40 1k of the Internal

Revenue Code All employees over

the age of 21 are eligible

to make pre-tax contributions

up to

specified percentage

of

their compensation

Under

the 401k Plan the Company may but

is not obligated to match

portion of the employees

contributions

up to

defined maximum Matching

contributions

of $0 $55018 and $127080

were made in

the years ended December

31 2010 2009 and 2008 respectively

The Company match was

suspended

on

July

2009 and was reinstated as of January

2011

Royalty Agreements

The Company has

royalty-free license from its founder which was received

in

fair market value

exchange in connection

with the formation

of the Company

for the proprietary

rights

to certain patented hair

analysis technology

used by the Company in its drug testing

services The Company has two agreements

to

sublicense its technology

which have not generated

significant

royalties

to date

10 Commitments and Contingencies

Commitments

The Company

leases certain

of

its facilities

and equipment under operating lease agreements

expiring

on

various dates through

February

2015 Total minimum lease payments

including

scheduled

increases are

charged

to operations on the straight-line

basis over

the life of

the respective lease Rent expense was

approximately

$558000 $534000 and $516000

in 2010 2009

and 2008 respectively

At December

31 2010 minimum commitments

remaining under

lease agreements

were approximately

as

follows

Years Ending December

31

2011

2012

2013

2014

2015

Thereafter

37

Amount

546000

534000

101000

103000

45000

9000

$1338000

PSYCHEMEDICS CORPORATION

NOTES TO FINANCIAL STATEMENTS
December 31 2010

10 Commitments and Contingencies

continued

Purchase Commitment

The Company has

supply agreement with

vendor which requires the Company to purchase

isotopes

used

in its drug testing

procedures

from this sole supplier

in exchange for variable annual payments based

upon prior year purchases Purchases

amounted to $431897 $584109 and $606484

in 2010 2009 and

2008 respectively

The Company

expects

to purchase

approximately

$569000

in 2011 In exchange for

exclusivity the supplier has provided

the Company with the right

to purchase

the isotope technology

at fair

market value

under

certain

conditions

including the failure to meet

the Companys purchase

commitments

This agreement

does

not

include

fixed termination date however

it is cancelable

upon

mutual agreement by

the parties

or six months after

termination

notice by the Company of

its intent

to use

different

technology

in

connection

with its drug

testing

procedures

Contingencies

The Company is subject

to legal

proceedings

and claims which arise in the ordinary

course of

its

business

The Company believes that although

there can

be no assurance

as

to the disposition

of

these

proceedings

based

upon

information

available to the Company

at this time the expected

outcome of these

matters would not have

material

impact

on the Companys results of operations or financial

condition

11 Selected Quarterly Financial

Data Unaudited

The following

are selected quarterly financial

data for

the years ended December

31 2010 and 2009

Revenues

Gross profit

Income from operations

Net

income

Basic net income per share

Diluted net income per share

Revenues

Gross profit

Income from operations

Net

income

Basic net

income per share

Diluted net income per share

Quarter Ended 000s Except per Share Amounts

March

31

2010

$4464

2554

836

506

0.09

0.09

June 30
2010

$5422

3380

1564

873

0.17

0.17

September 30
2010

December

31

2010

$5106

3026

1336

817

0.16

0.16

$5117

3082

678

418

0.08

0.08

Quarter Ended 000s Except per Share Amounts

March

31

2009

$4078

2092

53

39

0.01

0.01

June 30
2009

$3934

2106

298

174

0.03

0.03

September 30
2009

$4670

2890

1273

768

0.15

0.15

December

31

2009

$4271

2522

960

546

0.11

0.10

38

Item

Changes

in and Disagreements With Accountants

on Accounting

and Financial Disclosure

None

Item 9A

Controls

and Procedures

Disclosure Controls

and Procedures

The Company maintains disclosure controls and procedures

as defined in Exchange Act Rules 13a-15e

and 15d-15e that are designed
SEC are recorded processed
and forms and that

such

to ensure that

information

required to be disclosed in reports filed with the

summarized and reported within the time period specified by the SECs rules

information

is accumulated

and communicated

to our management

including

to our

Chief Executive

Office and Principal Financial Officer

as appropriate

to allow for timely decisions regarding

required disclosure

As required by Rule 13a-15

under

the Exchange Act the Companys management

with the participation

of

of

the Companys Chief Executive Officer and its Principal Financial Officer has evaluated
its disclosure controls and procedures

31 2010 Based

as of December

on this evaluation

the effectiveness

our Chief

Executive Officer and Principal Financial Officer concluded that

procedures

were effective

for ensuring that

information

the Companys disclosure controls and
required to be disclosed by the Company in the reports

that

it files or submits under

the Securities Exchange Act of 1934 is recorded processed

summarized and

reported within the time periods specified in the SECs rules

and forms and that

its disclosure controls and

procedures

were also effective

to ensure that

information

required to be disclosed in the reports

that

it files or

submits under

the Exchange Act is accumulated

and communicated

to management

including the Companys

principal executive

and financial

officers

to allow timely decisions regarding required disclosure

Changes

in Internal Control Over Financial Reporting

There were no changes

in the Companys internal

control

over

financial

reporting that occurred

during

the Companys last

fiscal quarter

that have materially affected or are reasonably

likely

to materially affect

the

Companys internal

control over

financial

reporting

Managements Report on Internal Control Over Financial Reporting

The Companys management

is responsible for establishing and maintaining

adequate

internal

control

over

financial

reporting as defined in Rules

3a- 15f and 15d- 15f under

the Exchange Act Under

the

supervision

and with the participation of management

including

our Chief Executive Officer and Principal

Financial Officer

the Company conducted

an evaluation of

the effectiveness of our internal

control over

financial

reporting based

on the framework

in Internal Control

Integrated Framework

issued by the

Committee

of Sponsoring

Organizations

of the Treadway Commission

Based

on the Companys evaluation

under

the framework

in Internal Control

Integrated Framework the Companys management

concluded

that

our

internal

control

over

financial

reporting was effective

as of December

31 2010

This annual

report does not

include an attestation

report of our independent

registered public accounting

firm regarding internal

control

over

financial

reporting Managements report was not subject

to attestation

by

our

registered public

accounting

firm pursuant

to temporary

rules of

the Securities and Exchange

Commission

that permit us to provide only managements

report

in this annual

report

Inherent Limitations

on Effectiveness

of Controls

The Companys management

including

its Chief Executive Officer and Principal Financial Officer does

not expect

that

the Companys disclosure controls and procedures

or the Companys internal

controls will

prevent

all error

and all fraud

control system no matter how well

conceived

and operated

can provide

only reasonable

not absolute assurance

that

the objectives for

the control

of

control

system must

reflect

the fact

that

there are resource

constraints

system are met Further
and the benefits

of controls must

the design

be considered

relative

to their costs Because

of the inherent

limitations

in all control systems no evaluation

of controls can provide absolute assurance

that all control

issues misstatements

errors

and instances of fraud

if any within our company

have been or will be prevented

or detected

Further

internal

controls may become

inadequate

as

result of changes

in conditions

or through

the deteriorations

of

the degree of compliance

with

policies or procedures

39

Item 9B Other Information

On March

24 2011

the Compensation Committee of
the Company approved the terms of cash performance

Corporation

the Board of Directors of Psychemedics

bonus arrangements

with certain

executive

officers including

the Companys Chief Executive Officer its Vice President

Laboratory

Operations its Vice President and Controller and other employees for 2011 the cash bonus arrangements

Bonus

payments under

the cash bonus arrangements

are calculated and paid as

follows

Each participant

has the opportunity

to earn as bonus compensation

up to an aggregate

of an additional

25% of his or her Base Salary in 2011 based

on achievement

of Company and individual performance

targets

Each participants

target percentages

consist of the following

Up to 10% of Base Salary based
income goals for 2011

on the Companys achievement

of pre-determined

revenue

and net

Up to 10% of Base Salary based

on the employees

achievement

of pre-determined

individual goals

for 2011

Up to 5% of Base Salary based

on the Companys achievement

of pre-determined

customer

service

goals for 2011

The Compensation Committee reserves the right

to withdraw amend add to and terminate the cash

bonus arrangements or any portion of

them in its discretion at any time including

but not

limited to

changing

or eliminating

the threshold amounts giving rise to the payment of

target percentages

determining

the calculation

of such

threshold amounts

and adjusting threshold amounts to take into account

special non

recurring

items in determining

financial

and individual performance

At the end of

fiscal year 2011 the Chief Executive Officer will

review

and assess the performance

of

each

of

the other participants

with respect

to achievement

of his or her individual

targets and provide his

recommendations

thereon

to the Compensation Committee

In addition

the Compensation Committee will

review

and assess the Chief Executive

Officers

performance

with respect

to achievement

of his

individual

targets The Compensation Committee will

then determine

the level of payout

of

the portion of the Chief

Executive

Officers

bonus arrangement

with respect

to individual and Company targets

and each

of

the other

participants

based

on the Committees

review

and assessment

of

the performance

of each

individual

toward

his or her individual

targets

and Company targets

40

PART III

Item 10 Directors

and Executive Officers

of the Registrant

Following

is

list

that

sets

forth

as of March 25 2011

the names ages

and positions within the

Company of all of

the Executive

Officers of

director

has been nominated for reelection at

the Company and the Directors of
the Companys 2011 Annual Meeting

the Company

Each such

to be held on May 24

2011

at 300 P.M at the Seaport Hotel 200 Seaport Boulevard Boston Massachusetts

Name

Raymond

Neil Lerner

Kubacki

James Dyke
Michael

Schaffer Ph.D

Harry Connick

Walter

Tomenson

Jr

Fred

Weinert

Age

66

43

46

66

85

64

63

Position

Chairman Chief Executive Officer President Director

Vice President Controller

Corporate

Vice President Sales

Marketing

Vice President Laboratory Operations

Director Audit Committee member Compensation Committee

Member Nominating Committee member
Director Audit Committee member Compensation Committee

Member Nominating Committee member

Director Audit Committee member Compensation Committee

Member Nominating Committee member

All Directors

hold office

until

the next annual meeting

of stockholders

or until

their successors

are

elected Officers

serve at the discretion of the Board of Directors

Mr Kubacki

has been the Companys President and Chief Executive Officer since 1991 He has also

served

as Chairman of the Board of the Company since 1993 He is

director

of

Integrated Environmental

Technologies LTD From 2007 until 2010 he served

as

director

of Protection One Inc and from 2004 to

2007 he served

as

director of

Integrated Alarm Services Group Inc He is also

trustee of the Center

for

Excellence

in Education

based

in Washington D.C and holds an Advanced

Professional Director Certification

from the American College of Directors

As

result of these and other professional

experiences Mr Kubacki

possesses

collective

particular

and experience
qualifications skills and experience Mr Kubacki has been

knowledge

in marketing

and operations that strengthen the Boards

director

of

the Company since 1991

Mr Lerner

joined the Company as Vice President and Controller in October

2010 Prior to joining the

Company
Controller with Atlas TMS Divisional Controller with Mastec

of Operational Accounting

as Director

he served

at Beacon

Roofing Supply Inc Corporate

Inc and multiple roles with Johnson

Johnson including

plant controller in the Netherlands Mr Lerner

is Certified Public Accountant

Mr Dyke

joined the Company as Corporate

Vice President Sales and Marketing

in April 2010 Prior to

joining the Company

he worked as

Strategic Sales Consultant and held

variety of Vice President of

Sales/Sales

Marketing and General Management

positions with Pitney Bowes Inc in Canada the United

Kingdom and United

States

Dr Schaffer has served

as Vice President of Laboratory Operations

since 1999 From 1990 to 1999

he

served

as Director

of Toxicology Technical

Manager

and Responsible

Person

laboratory

of SmithKline

Beecham Clinical Laboratories

From 1990 to 1999

for the Leesburg Florida
he was also member of the

Board of Directors of

the American Board of Forensic Toxicologists Dr Schaffer has been an inspector

for

the Substance

Abuse

and Mental Health

Services Administrations

National Laboratory Certification

Program

since 1989

Mr Connick

served

as District Attorney

for Orleans Parish New Orleans LA from 1974 to 2003 In

2002 Mr Connick

received

from Drug Czar John

Walters

the Directors

Award

for Distinguished

Service

in recognition of exemplary accomplishment

result of

these and other professional

and distinguished
experiences Mr Connick

service in the fight against

illegal drugs As

possesses

particular

knowledge

and experience

in law enforcement

and the effects

of drugs of abuse

and their effect

on society that strengthen the Boards

collective

qualifications skills and experience Mr Connick

has been

director

of the Company

since 2003

41

Mr Tomenson

is

Senior Advisor to Integro Ltd Mr Tomenson

was Managing Director

and Chairman

of Client Development

of Marsh Inc from 1998 until 2004 From 1993
services division of Marsh Inc Mr Tomenson

is

to 1998

he was chairman of

Director

of

the Trinity College

FINPRO the financial
School Fund Inc He also serves on the Executive

Council of

the Inner-City Scholarship

Fund

and holds

Master Professional Director Certification

from the American College of Directors As

result of

these and

other professional

experiences Mr Tomenson

possesses

particular

knowledge

and experience

in marketing

and

distribution

and human resources

that strengthen the Boards

collective

qualifications skills and experience

Mr Tomenson

has been

director

of the Company since 1999

Mr Weinert

is an entrepreneur whose

current activities

are concentrated

in real

estate

and new business

development

He has served

on the Business Advisory Council

for

the University

of Dayton for over 20 years

From 1973

until 1989 Mr Weinert

held various executive

positions in the Finance

and Operations

groups of

Waste Management

Inc and its subsidiaries

including

years as

the President of Waste Management

International

Inc As

result of

these and other professional

experiences Mr Weinert

possesses

particular

knowledge and experience

in accounting

that strengthen the Boards

collective

the Company since 1991

finance capital

structures
qualifications skills and experience Mr Weinert

distribution

and international operations

has been

director

of

The information

required by Item 405 of Regulation

S-K will be set

forth in the Proxy Statement

of

the

Company relating

to the 2011 Annual Meeting of Stockholders

to be held on May 24 2011 and is

incorporated

herein by reference

The Company has

code

of ethics

that applies to all employees and non-employee directors This code

satisfies

the requirements

set

forth

in Item 406 of Regulation

S-K and applies to all relevant

persons

set

forth

therein The Company will mail
and without charge Such

to interested parties

copy of

the Code of Ethics upon written request

request shall be made to our General Counsel

125 Nagog Park Acton

Massachusetts

01720

Item 11 Executive Compensation

The information

required by this item will be set

forth

in the Proxy Statement

of the Company relating

to

the 2011 Annual Meeting of Stockholders

to be held on May 24 2011

and is incorporated

herein by reference

Item 12 Security Ownership
Matters

of Certain Beneficial Owners and Management and Related Stockholder

The information

required by this item will be set

forth

in the Proxy Statement

of the Company relating

to

the 2011 Annual Meeting

of Stockholders

to be held on May 24 2011

and is incorporated

herein by reference

Item 13 Certain Relationships

and Related Transactions

and Director

Independence

The information

required by this item will be set

forth

in the Proxy Statement

of the Company relating

to

the 2011 Annual Meeting

of Stockholders

to be held on May 24 2011

and is incorporated

herein by reference

Item 14 Principal Accounting

Fees and Services

The information

required by this item will be set

forth

in the Proxy Statement

of the Company relating

to

the 2011 Annual Meeting

of Stockholders

to be held on May 24 2011

and is

incorporated

herein by reference

42

Item 15 Exhibits Financial Statement Schedules

PART IV

Financial Statements

required by Item 15 are included and indexed

in Part II Item

Financial Statement

Schedules

included in Part

IV of

this report Schedule

II

is omitted because

information

is included in Notes

to Financial Statements All other schedules

under

the accounting

regulations

of the SEC are not required under

the related instructions

and are inapplicable and thus have been omitted

See Exhibit

Index included elsewhere

in this Report

43

Pursuant

to the requirements of Section

13 or 15d of the Securities Exchange Act of 1934

the

registrant

has duly caused

this Report

to be signed

on its behalf by the undersigned thereunto duly authorized

SIGNATURES

Date March 25 2011

PSYCHEMEDICS CORPORATION

By Is Raymond

Kubacki

Raymond

Kubacki

Chairman

President and Chief Executive Officer

Pursuant

to the requirements of

the Securities Exchange Act of 1934

this Report

has been signed below

by the following

persons

on behalf of

the Registrant and in the capacities and on the dates indicated

POWER OF ATTORNEY

KNOW ALL PERSONS BY THESE PRESENTS

that each

person whose

signature appears below

appoints jointly

and severally Raymond

Kubacki

and Neil Lemer and each

one of

them his attorneys-in-

fact

each with the power of substitution

for him in any and all capacities

to sign any and all amendments

to

this Annual Report

on Form 10-K and to file the same with exhibits thereto and other documents in

coimection

therewith with the SEC hereby

ratifying

and confinning

all

that

each attorneys-in-fact or his

substitute

or substitutes may do or cause

to be done by virtue hereof

Is Raymond

Kubacki

Chairman President and Chief Executive Officer

March 25 2011

Raymond

Kubacki

Director

Principal Executive Officer

Is Neil Lerner

Neil Lemer

Is Harry Connick

Harry Connick

Vice President Controller

March 25 2011

Principal Financial

and Accounting Officer

Director

March 25 2011

Is Walter

Tomenson

Jr

Director

March 25 2011

Walter

Tomenson

Jr

Is Fred

Weinert

Director

March

25 2011

Fred

Weinert

44

Exhibit

Number

EXHIBIT INDEX

Description

3.1

Amended and Restated Certificate

of Incorporation

by reference from the Registrants Quarterly Report

filed on August
on Form 10-Q for

2002

Incorporated

the Quarter ended

September 30 2002

3.2

By-Laws

of the Company

Incorporated

by reference from the Registrants Annual Report

on Form 10-K for the fiscal

year

ended December

31 2001

4.1

Specimen Stock Certificate

Incorporated

by reference from the Registrants Registration

Statement

on Form 8-A filed on July 31 2002

10.1

License Agreement with Werner Baumgartner Ph.D and Annette Baumgartner

dated

January

17 1987

Incorporated

by reference from the Registrants Registration

Statement

10.2.1

10.2.2

on Form S-18 File No 33-10186 LA
Lease dated October

1992 with Mitchell

Hersch

et

with respect

to premises

in

Culver City California

Incorporated

by reference from the Registrants Annual Report

on

Form 10-KSB

for the fiscal year ended December

31 1992

Security Agreement
reference from the Registrants Annual Report on Form 10-KSB

dated October

1992 with Mitchell

Hersch et

Incorporated

by

for

the fiscal year ended

December

31 1992

10.2.3

First Amendment to Lease dated with Mitchell

Hersch et.al California

Incorporated

by

reference from the Registrants Annual Report

on Form 10-K for

the fiscal

year

ended

December

31 1997

10.2.4

Second Amendment to Lease

dated with Mitchell

Hersch

et.al California

Incorporated

by reference from the Registrants Annual Report on Form 10-K for
December

31 1997

the fiscal year

ended

10.2.5

Third Amendment to Lease dated December

31 1997 with Mitchell

Hersch et.al

California

Incorporated

by reference from the Registrants Annual Report

on Form 10-K

for the fiscal

year

ended December

31 1997

10.2.6

Fourth Amendment to Lease dated May 24 2005 with Mitchell

Hersch

et.al

California

Incorporated

by reference from the Registrants Annual Report

on Form 10-K

for the fiscal

year

ended December

31 2005

10.2.7

First Amendment to Lease dated December

10 1999 with Isabelle Greenspan

et.al California

5840 Uplander Way

10.3

10.4

2000 Stock Option Plan
on Form 10-Q for the Quarter ended September 30 2002
Amended and restated change

Incorporated

in Control

Severance

Agreement with Raymond

Kubacki

by reference from the Registrants Quarterly Report

dated July 10 2008

Incorporated

by reference from the Registrants

current

report on

form 8-k filed on July 14 2008

10.5

2006 Equity Incentive Plan

Incorporated

by reference from the Registrants Current Report

10.6

10.7

on Form 8-K filed on May 17 2006
Form of Stock Unit Award

used with employees and consultants under

the 2006 Equity

Incentive Plan

Incorporated

by reference from the Registrants Current Report

on

Form 8-K filed on May 17 2006
Form of Stock Unit Award

used with non-employee

directors

under

the 2006 Equity Incentive

Plan

Incorporated

by reference from the Registrants Current Report

on Form 8-K filed on

May 17 2006

10.8

Change

in control

severance

agreement with Michael Schaffer PhD dated July 10 2008

Incorporated

by reference from the registrants current

report on Form 8-k filed on July 14

10.9

2008
Amendment dated November

2008 to change

in control

severance

agreement with Ray

Kubacki

Incorporated

by reference from the Registrants Annual Report

on Form 10-K for

the fiscal

year

ended December

31 2008

45

Exhibit

Number

Description

10.10

Amendment dated November

2008 to change

in control

severance

agreement with Michael

Schaffer

Incorporated

by reference from the Registrants Annual Report

on Form 10-K for

the fiscal year ended December

31 2008

10.11

Employment

offer

letter dated April

Registrants Quarterly Report

10.12

Change

in Control

Severance

2010 with James Dyke incorporated
on Form 10-Q for the quarter ended June 30 2010
Agreement with James

by reference from

Dyke dated April 72010 Incorporated
on Form 10-Q for the quarter ended June 30

by reference from Registrants Quarterly Report

2010

10.13

23.1

31.1

Employment
Consent of BDO USA LLP Independent

letter dated October

offer

25 2010 with Neil Lerner

Registered

Public Accounting Firm

Certification

of Chief Executive Officer Pursuant

to Section

302 of

the Sarbanes-Oxley

Act of 2002

31.2

Certification

of Vice President and Controller Pursuant

to Section

302 of

the Sarbanes-Oxley

Act of 2002

32.1

Certification

of Chief Executive Officer Pursuant

to 18 U.S.C Section

1350 as Adopted

Pursuant

to Section

906 of the Sarbanes-Oxley

Act of 2002

32.2

Certification

of Vice President and Controller Pursuant

to 18 U.S.C Section

1350 as Adopted

Pursuant

to Section

906 of the Sarbanes-Oxley

Act of 2002

Management

compensation

plan or arrangement

46

MANAGEMENT AND CORPORATE INFORMATION

BOARD OF DIRECTORS

Kubacki
Raymond
Chairman President and C.E.O

Harry Connick

Private Investor

Walter

Tomenson Jr

Senior Advisor

Integro Ltd

Fred

Weinert

Private Investor

CORPORATE OFFICERS

Raymond
Chairman President and C.E.O

Kubacki

Michael

Schaffer Ph.D

Vice President-Laboratory

Operations

Neil Lerner

Vice President

Finance

James Dyke

AUDITORS

BDO USA LLP

Boston Massachusetts

CORPORATE OFFICES

Corporate Headquarters

125 Nagog Park

Acton Massachusetts

01720

Laboratory Facilities

5832 Uplander Way

Culver City California 90230

FORM 10K

copy of the Companys Form 10-K as

filed with the

Secunties

and Exchange

Commission may be obtained

by any stockholder

at our website

www.psychernedics

corn

or by writing to

Corporate

Vice President Sales

Marketing

Investor Relations

TRANSFER

AGENT

do Computershare

Trust Company N.A

P.O Box 43078

Providence RI 02940-3078

Investor Relations Telephone

Number

1-800-426-5523

Internet Address

http//www.computershare.com

COUNSEL

Lynch Brewer Hoffman

Fink LLP

Boston Massachusetts

Psychemedics Corporation

125 Nagog Park
Acton MA 01720

ANNUAL MEETING

The 2011 Annual Meeting of Stockholders
held on May 24 2011 at 300 p.m at

will be

The Seaport Hotel

200 Seaport Boulevard

Boston Massachusetts

NASDAQ Stock Exchange

Symbol PMD

PSYCHEMEDICS
CORPORATION

125 NAGOG PARK ACTON MA 01720