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Worldwide Healthcare Trust PLC

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FY2010 Annual Report · Worldwide Healthcare Trust PLC
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Finsbury Worldwide Pharmaceutical Trust PLC
25 Southampton Buildings, London  WC2A 1AL
www.finsburywp.com

2010

F I N S B U RY  W O R L D W I D E  
P H A R MAC E U T I C A L  T R U S T   P LC

A N N UA L   R E P O R T &   F I N A N C I A L   S TAT E M E N TS
F O R  T H E  YE A R   E N D E D   3 1   MA R C H   2 0 1 0

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ACC E S S I N G  T H E   G LO B A L   MA R K E T

Pharmaceuticals and biotechnology are worldwide industries and accessing the global market as a UK investor can be difficult.
Within the UK, there are diminishing options for investment as the universe of companies is shrinking through mergers and
acquisitions. Finsbury Worldwide Pharmaceutical Trust PLC offers an opportunity to gain exposure to the pharmaceutical and
biotechnology sectors on a global scale.

I N V E S T M E N T   O B J E C T I V E   A N D   P O L I C Y

Finsbury Worldwide Pharmaceutical Trust PLC invests worldwide in pharmaceutical, biotechnology and related companies in the
healthcare sector with the objective of achieving a high level of capital growth. In order to achieve its investment objective, the
Company invests in a diversified portfolio of shares in pharmaceutical and biotechnology companies and related securities on a
worldwide basis. It uses gearing and derivative transactions to mitigate risk and also to enhance returns. Further details of the
Company’s investment policy are set out in the Report of the Directors on page 14. Details of a proposed change to the
Company’s investment policy are set out in the Chairman’s Statement on page 3.

CO N T I N UAT I O N  V OT E

The next continuation vote of the Company shall be held at the Annual General Meeting in 2014, and further opportunities to
vote on the continuation of the Company shall be given to shareholders every five years thereafter.

G E A R I N G

The Company’s borrowing requirements are met through the utilisation of a loan facility, repayable on demand provided by
Goldman Sachs & Co. New York. At the date of this Annual Report £24.1m was drawn down from this facility.

A N N UA L   G E N E R A L   M E E T I N G

The Annual General Meeting of the Company will be held at the Barber-Surgeons’ Hall, Monkwell Square, Wood Street, London
EC2Y 5BL on Thursday, 15 July 2010 at 12 noon.

1
Performance Summary
2-3
Chairman’s Statement
4-5
Your Board
6
A Special Relationship
7-10
Review of Investments
11
Champions of Innovation
12
Portfolio
13
Analysis of the Portfolio
Report of the Directors Incorporating the Business Review 14-24
Statement of Directors’ Responsibilities
25
26-31
Corporate Governance
31
Shareholder Analysis

Directors’ Remuneration Report
Independent Auditors’ Report
Income Statement
Reconciliation of Movements in Shareholders’ Funds
Balance Sheet
Cash Flow Statement
Notes to the Financial Statements
Notice of Annual General Meeting 
How to Invest
Glossary
Company Information
Disability Act

32-33
34-35
36
37
38
39
40-55
56-60
61
62
63
63

The Company is a member of the Association of Investment Companies.

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01

P E R F O R MA N C E   S U M MA RY

Shareholders’ funds 
Net asset value per share – diluted~
(dilution for warrants/subscription shares)

Net asset value per share – basic

Share price 

Premium/(discount) of share price to diluted 
net asset value per share 

Premium/(discount) of share price to basic 
net asset value per share 
Benchmark Index†
Total expense ratio (excluding performance fees)#

*31 March
2005

31 March
2006

31 March
2007

31 March
2008

31 March
2009

31 March
2010

£226.4m  £334.8m  £273.6m  £224.8m  £263.0m £346.2m

414.7p 

564.1p 

511.2p 

414.7p 

583.0p 

520.9p 

430.0p 

575.0p 

477.8p 

482.4p 

486.6p 

457.0p 

600.5p

635.9p

550.5p

752.7p

780.8p

701.5p

3.7%

1.9% 

(6.5%) 

(5.3%) 

(8.3%)

(6.8%)

3.7% 

(1.4%) 

(8.3%) 

(6.1%) 

(13.4%)

(10.2%)

6,173.2 

7,787.8 

7,507.7 

7,049.7 

8,101.0

10,094.2

1.5% 

1.4% 

1.3% 

1.3% 

1.2%

1.0%

% Change for 
the year ended
31 March
2010

31.6

25.3

22.8

27.4

N/A

N/A

24.6

N/A

*
†
~

#

Restated for accounting policy introduction of FRS 26 and FRS 21.
Datastream World Pharmaceutical and Biotechnology Index, (total return, sterling adjusted).
There was no dilution in years prior to 2006. Dilution for conversion of all outstanding warrants at the conversion price of 464p and the conversion of all outstanding
subscription shares at a conversion price of 614p (see note 14 on page 48).
Excludes indexation of the deferred fee paid to M and I Investors, Inc. on 24 January 2006. However, this includes the VAT repayment of £255,000 received during the
year ended 31 March 2010. 

P E R F O R MA N C E TO   3 1   MA R C H   2 0 1 0

900

800

700

600

500

400

300

200

100

0

Apr
95

Mar
96

Mar
97

Mar
98

Mar
99

Mar
00

Mar
01

Mar
02

Mar
03

Mar
04

Mar
05

Mar
06

Mar
07

Mar
08

Mar
09

Mar
10 

Finsbury Worldwide  Net Asset Value (total return)

Finsbury Worldwide Share Price (total return)

Benchmark Index

Rebased to 100 as at 28 April 1995
Source: Morningstar & Thomson Reuters

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02

Chairman’s Statement

THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION.

If you are in any doubt about any aspect of the proposal described in this document or as to the action you should take,
you should consult your stockbroker, bank manager, solicitor, accountant or other appropriate independent adviser.

If you have sold or otherwise transferred all your ordinary shares of 25p each in Finsbury Worldwide Pharmaceutical
Trust PLC (the “Company”), please forward this document to the purchaser or transferee, or to the bank, stockbroker
or other agent through whom the sale or transfer was effected, for transmission to the purchaser or transferee.

R E V I E W   O F  T H E
YE A R   A N D
P E R F O R MA N C E

I am pleased to report that during
the year ended 31 March 2010 the
Company’s diluted net asset value
per share rose by 25.3% compared
to a rise of 24.6% in the Company’s
benchmark index during the same
period. The Company benefitted

Martin Smith

from solid investment performance across its holdings, ranging
from large pharmaceutical companies such as Novartis, Johnson
& Johnson and Shire to emerging Hong Kong based
pharmaceutical company Sinopharm and US biotechnology
company Dendreon. The Company’s performance in sterling
terms was achieved despite the appreciation of sterling against
the U.S. dollar during this period and uncertainty surrounding
President Obama’s U.S. healthcare reform proposals.

During the year, the Company’s share price rose by 27.4% and
the discount of the share price to diluted net asset value per
share narrowed to close at 6.8% compared to 8.3% a year ago.
This discount level at the year end was slightly wider than the 6%
target, however I would like to remind shareholders that it
remains possible for the share price to trade outside the discount
target from time to time, the discount reflecting the balance of
supply and demand for the Company’s shares on any one day.

Further information on the Company’s investments can be
found in the Review of Investments beginning on page 7.

C A P I TA L

In implementing its policy of actively managing the discount by
buying back shares at prices representing a discount greater
than 6% to the diluted net asset value per share, if there is
demand in the market for it to do so, a total of 8,508,938 shares
was repurchased by the Company during the year at a cost of
£48.5m (including expenses). The Company’s share buy-back
authority was renewed at a General Meeting held on 2 March
2010 when authority was granted to repurchase 6,716,138
shares; a total of 2,105,102 shares have so far been repurchased

for treasury under this authority. I would like to remind
shareholders that the Board has resolved that any shares held in
treasury will be cancelled on the date of the Annual General
Meeting each year and consequently all shares held in treasury
on 15 July 2010 will be cancelled.

Shareholder approval to renew the authority to repurchase the
Company’s shares will be sought at the Annual General Meeting.

The final exercise date for the Company’s warrants was 31 July
2009 and all of the remaining warrants in issue on that date
were converted into shares. As a result, 10,745,610 new shares
were issued by the Company on 5 August 2009, raising £49.9m
of additional funds for the Company. 

On 4 September 2009, the Company undertook a bonus issue of
subscription shares on the basis of one subscription share for
every five ordinary shares held at that date. The subscription
shares have quarterly subscription dates and so far a total of
1,019,447 new shares have been issued, raising £6.3m of
additional funds for the Company, as a result of holders of
subscription shares exercising their subscriptions rights. 

REVENUE AND DIVIDENDS

The revenue return for the year was £4.2 million
(2009: £2.4 million) and the Board, in order to maintain
investment trust status, has declared an interim dividend of
8.5p per share, compared to last year’s interim dividend of
5.0p per share, an increase of 70%. Based on the current share
price of 657.25p that represents a yield of 1.3%.

The interim dividend will be payable on 26 July 2010 to ordinary
shareholders on the register of members on 25 June 2010. The
associated ex-dividend date will be 23 June 2010.

GEARING

The Company’s borrowing requirements are met through a loan
facility, which is repayable on demand, provided by the
custodian Goldman Sachs & Co New York. At the time of writing
a total of £24.1m of this facility has been drawn down.

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ALTERNATIVE INVESTMENT FUND
MANAGER (‘AIFM’) DIRECTIVE

There is currently draft legislation under consideration in Europe,
the AIFM Directive, designed to regulate ‘alternative investment
funds’ including investment trusts. Our trade association, the
Association of Investment Companies, continues to work
towards ensuring that the AIFM Directive is drafted to
accommodate the UK investment company structure. Your
Board will continue to keep shareholders informed of major
developments concerning the Directive as they arise.

OUTLOOK

2009 saw a remarkable recovery in the fortunes of global
markets due, in part, to radical and unprecedented stimulus
packages from central governments; however, there still remains
a degree of uncertainty concerning the rate of global economic
recovery. The removal of the uncertainty surrounding healthcare
reform in the U.S. should continue to benefit the sector and this,
together with a combination of low valuations and strong
earnings growth potential, continued merger and acquisition
activity and a number of anticipated high profile product
approvals are all positive indicators for the future. Your Board
believes that the Company is well positioned to take advantage
of these factors and so remains optimistic for the Company’s
future performance. The Board would like to thank shareholders
for their continued support. I would also like to thank our
Investment Manager and our Manager for their hard work
during the year.

PROPOSED CHANGE TO INVESTMENT
POLICY

Under the Listing Rules the Company is required to seek the
approval of shareholders for any material change to its
investment policy and any related party transaction and so I set
out below information about some proposed changes. An
ordinary resolution to approve these changes will be proposed
at the Company’s Annual General Meeting to be held at
12 noon on Thursday, 15 July 2010 at the Barber-Surgeons Hall,
Monkwell Square, Wood Street, London EC2Y 5BL.

The Company’s investment policy is to invest worldwide in
pharmaceutical, biotechnology and related companies in the
healthcare sector with the objective of achieving a high level of
capital growth. Our Investment Manager believes that it would
be beneficial to shareholders to broaden the definition of the
healthcare sector as referred to within the investment policy, to
include companies in the healthcare equipment and healthcare
technology sectors and also to include companies that provide
healthcare and related services. None of these three areas of the
healthcare sector will represent more than 15% of the portfolio
at the date of acquisition and any investment made will be
subject to the Company’s existing investment limitations and
guidelines, details of which, together with the Company’s
current investment policy, can be found on page 14.

As a consequence of this development, the Board is proposing a
change from the Company’s existing benchmark index which is
the Datastream World Pharmaceutical and Biotechnology Index
(measured in sterling terms on a total return basis), to the MSCI
World Healthcare Index (measured in sterling terms on a total
return basis). Your Board believes that this index will more
accurately reflect the makeup of the Company’s portfolio.
Further details of the changes are set out at page 21.

Your Board strongly supports the investment philosophy and
approach of our Investment Manager, OrbiMed Capital LLC, and
is of the view that these changes will be of benefit to
shareholders. 

PROPOSED CHANGE OF NAME

In addition, and as a direct consequence of the proposals
discussed above, a special resolution will be proposed at the
Annual General Meeting to change the Company’s name from
Finsbury Worldwide Pharmaceutical Trust PLC to Worldwide
Healthcare Trust PLC, which your Board believes more accurately
describes the Company today and going forward.

Martin Smith
Chairman
21 June 2010

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04

Your Board

P R O F E S S O R
D U N C A N   G E D D E S * +
Professor Geddes, aged 68, joined
the Board at launch in 1995 and
has been designated as the Senior
Independent Director. An author of
numerous publications on
respiratory medicine, Professor
Geddes is self-employed.  

PAU L   G AU N T +
Paul Gaunt, aged 61, joined the Board at launch in 1995. Paul is
self-employed and has 30 years’ experience in the investment
industry. He was formerly Senior Investment Manager and an
Assistant General Manager of  The Equitable Life Assurance
Society and a Director of Brit Insurance Holdings PLC and Oasis
Healthcare PLC. Paul is a Director of RCM Technology Trust PLC
and also of The Biotech Growth Trust PLC; OrbiMed Capital LLC,

the Company’s Investment
Manager, also acts as Investment
Manager for The Biotech Growth
Trust PLC.

The Board of Directors, all of whom are non-executive,
supervise the management of Finsbury Worldwide
Pharmaceutical Trust PLC and look after the interests of
shareholders.

MA R T I N   S M I T H +
(C H A I R MA N )
Martin Smith, aged 67, joined the
Board in 2007. He was a founder of
Phoenix Securities, a private
investment banking firm. Following
the acquisition of Phoenix in 1997
by Donaldson Lufkin and Jenrette
(DLJ), he chaired DLJ’s European

Investment Banking Group. He subsequently founded and was
a non executive director of New Star Asset Management
Group PLC. He attended Oxford University and has an MBA
from Stanford University.

J O S E P H I N E   D I XO N * +
Josephine (“Jo”) Dixon, aged 50, joined the Board in 2004. A
Chartered Accountant, having trained with Deloitte & Co. in
London, Jo is Chairman of the Audit Committee.  Jo is self-
employed and is also a non-executive director of Baring

Emerging Europe PLC. Until 2003 Jo
held a number of senior executive
positions in investment banking,
leisure and support services. She
currently acts as a consultant to a
number of companies.

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05

D R   DAV I D
H O L B R O O K * +
Dr David Holbrook, aged 50, joined
the Board in 2007. He is a qualified
physician and a Director of MTI
Partners Limited, a leading
technology venture capital investor.
He attended London and Oxford
Universities, and has an MBA from

A N T H O NY
TO W N S E N D * +
Anthony Townsend, aged 62,
joined the Board at launch in 1995.
Anthony has spent 40 years
working in the City and was
Chairman of The Association of
Investment Companies from 2001
to 2003.  Anthony is Chairman of

Harvard Business School. He has held senior positions in a
number of blue chip biopharmaceutical organisations
including GlaxoSmithKline and Roche. 

iimia Investment Trust plc, British & American Investment Trust
PLC, F&C Global Smaller Companies PLC, Finsbury Growth &
Income Trust PLC and Baronsmead VCT 3 plc.

S A M U E L   D   I S A LY +
Sam Isaly, aged 65, joined the Board at launch in 1995. Sam is
Managing Partner of OrbiMed Capital LLC, the Company’s

Investment Manager, and has been
an international pharmaceutical
investment specialist for more than
20 years having worked in New
York and Europe with Chase
Manhattan, Société Générale, Crédit
Suisse and UBS Warburg.

Other than those stated above, none of the Directors has any
other connections with the Investment Manager and is not
employed by any of the companies in which the Company
holds an investment.

*
Member of the Audit Committee.
+
Member of the Nominations and Management Engagement and
Remuneration Committees.

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06

A Special Relationship

F I N S B U RY  W O R L D W I D E   P H A R MAC E U T I C A L  T R U S T   P LC   O U TS O U R C E S
T H E   MA N AG E M E N T   O F   I TS P O R T F O L I O  TO   O R B I M E D   C A P I TA L   L LC ,   A
N E W  YO R K   B A S E D   B O U T I Q U E   CO M PA NY  W H I C H   S P E C I A L I S E S
E XC LU S I V E LY   I N  T H E   MA N AG E M E N T   O F   A S S E TS   I N  T H E   G LO B A L   H E A LT H
S C I E N C E S   I N D U S T RY.   P E R S O N A L   I N V E S T M E N T,  T H R O U G H   CO M PA NY
O W N E R S H I P,   M E A N S  T H AT  T H E  T E A M   I S   CO M M I T T E D  TO   P R O D U C I N G
E XC E L L E N T   P E R F O R MA N C E .  

OrbiMed has managed the portfolio since the Company’s
launch in 1995, and the many awards won by the Company
over the years are a testament to the strength and talent
harnessed by the OrbiMed team.

OrbiMed had approximately US$5 billion in assets under
management as at 31 March 2010, across a range of funds,
including investment trusts, hedge funds and private equity
funds. OrbiMed’s investment management activities were
founded in 1989 by Samuel D Isaly.

OrbiMed Capital LLC – Investment Manager

OrbiMed emphasises investments in companies with under-
appreciated products in the pipeline, high quality
management teams and adequate financial resources.

A disciplined portfolio construction process is utilised to
ensure that the portfolio is focused on 30 to 40 ‘high
conviction’ positions.

Finally, the portfolio is subject to a rigorous risk management
process to moderate portfolio volatility.

T H E  T E A M  
OrbiMed’s investment team, headed up by Samuel D Isaly,
includes over 30 experienced professionals with expertise in
science, medicine, finance and law, many of whom have
advanced degrees and broad experience in science and
medicine. Collectively, the team currently serves on the boards
of over 25 biotechnology and healthcare companies.

With a coverage universe of over 750 public companies,
OrbiMed’s professionals maintain an exceptional level of
research intensity. The team has a demonstrated record of
investing successfully across market cycles in both public and
private companies.

I N V E S T M E N T   S T R AT E G Y   A N D
P R O C E S S
‘Bottom-up’ fundamental research provides the investment thesis
for all positions. In addition to meeting frequently with industry
executives and healthcare practitioners, OrbiMed attends many
major medical conferences worldwide. Portfolio positions are
discussed and selected during daily portfolio management
meetings. OrbiMed invests with a worldwide perspective,
selecting ideas from across all major geographical markets.

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Review of Investments 

07

We present with pleasure our 15th
annual Review of Investments for
Finsbury Worldwide Pharmaceutical
Trust PLC.

P E R F O R MA N C E
R E V I E W

The year ended 31 March 2010 was
a challenging one. With broader
markets recovering after the worst

Samuel D Isaly

financial market collapse in a generation, historic healthcare
reform being passed in the U.S. and currency markets
displaying continued volatility, the year certainly provided its
share of headwinds. But the Company’s returns proved they
were surmountable.

The Company’s diluted net asset value per share increased by
25.3% during the year. This result compares to a return of
24.6% from our benchmark, the Datastream World
Pharmaceutical and Biotechnology Index (measured in sterling
terms on a total return basis). Since inception in 1995, the
cumulative increase of the Company’s undiluted net asset
value per share now measures 708% compared to a
cumulative increase of 354% in the benchmark index.

While not as volatile as the Company’s previous financial year,
there were still major currency movements in 2010. Notably,
the U.S. dollar weakened against sterling by 5.8% in the year. As
a significant majority of the portfolio holdings are
denominated in U.S. dollars (70% as of 31 March 2010) this had
a negative drag on the Company’s reported returns this year.
Thus far in 2010 the dollar has appreciated significantly against
sterling, providing support for returns to date in the new
financial year.

D I V E R S E   CO N T R I B U T I O N  TO
P E R F O R MA N C E

Successful performance came in a variety of subsectors and
geographies in 2010. First and foremost, the top contributor to
performance this year was the Swiss drug giant, Novartis. A
considerable amount of positive pipeline and earnings news
flowed throughout the year. We also believe the truly

diversified healthcare platform that Novartis is building
(pharmaceuticals, generics, vaccines, and consumer) is finally
being rewarded by investors. The addition of ophthalmology
leader, Alcon, to the Novartis group adds another diverse
element to the business. 

The number two contributor in 2010 came as a result of a
Chinese initial-public-offering (“IPO”) involving a leading
pharmaceutical distributor, Sinopharm. Since the IPO in
September of 2009, the stock has more than doubled.
Sinopharm’s business model of aggressive acquisitions in this
space has been well rewarded. We expect future growth rates
to remain very attractive.

Another top contributor during the year was Dendreon, the
maker of a novel therapeutic vaccine for the treatment of
prostate cancer, Provenge. This U.S.-based company
announced stellar data in April 2009 that convinced us that
Provenge will be a “blockbuster product”. The stock remains a
core holding in the portfolio and it has, in our view, a good
chance of being acquired by a large drug company.

Our fourth biggest contributor in 2010 was a UK company,
Shire Pharmaceuticals. This underappreciated growth story
together with solid business fundamentals finally received
some recognition this past year, in terms of share price
appreciation. 

Finally, rounding out the top five contributors to performance
was the U.S.-based global healthcare leader, Johnson &
Johnson. Like Novartis, the share price increase was in part due
to the diverse nature of the company, with exposure to
pharmaceuticals, devices, diagnostics, and consumer markets.
However, Johnson & Johnson is also the first of the major
pharmas to emerge from its “patent cliff”, which for them was
in 2009 and 2010 compared to the industry low point in 2012.
With few remaining patent concerns coupled with a strong
earnings recovery, J&J boasts possibly the best new product
flow of any major pharmaceutical company and yet still
possesses a pipeline with several potential blockbusters in late
stage development.

The only significant area of weak performance in the portfolio
came from major biotechnology companies. While we
continue to believe that current valuations are at historical

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Review of Investments (continued)

lows, a number of company-specific events have led this
group of companies to underperform other segments of
healthcare. For example, Genzyme, a flagship biotechnology
company, has been beset by manufacturing challenges that
have prevented the company from producing several key
products in sufficient quantities. We continue to believe that
the depressed valuations of these companies will eventually
be recognised either by financial investors or strategic
acquirers.

H E A LT H C A R E   R E F O R M   PA S S E S  
–   F I N A L LY

Since Barack Obama was sworn in as the 44th President of the
United States in January 2009, a major focus for investors has
been the potential legislative changes to the U.S. healthcare
system. It has taken just over one year for the speculation to
become law: March 2010 bore witness to an historic event in
the United States as a major healthcare reform bill was passed
by both the House and Senate and signed into law by
President Obama. We believe this to be a net positive for the
healthcare sector and in particular the pharmaceutical
industry. While there may be some near term earnings
pressure on the margin for some pharmaceutical companies,
in the long term the addition of 30 million new entrants into
the healthcare insurance and drug coverage markets will
benefit the industry. 

Importantly, this bill contains no provisions that will impose
price controls or introduce the federal government as a major
buyer of drugs, a scenario that was considered by many as the
worst case scenario. In fact, the term “reform” as applied to this
legislation is somewhat misleading. Rather, this new law
essentially expands the current Medicaid and Medicare
programmes, simply allowing more individuals to qualify. While
pharmaceutical companies had to help pay for this expansion
through increased drug rebates to both programmes, it is
expected to cost the industry only $8 billion per year over
10 years (or $80 billion of the nearly $1 trillion total price tag).
Note that the U.S. pharmaceutical market reached over $300
billion in 2009. Thus, we believe that over time, the additional
lives under coverage and the commensurate increase in drug
consumption will more than offset any rebate pressure. 

M E R G E R S   A N D   ACQ U I S I T I O N S  TO
CO N T I N U E  

This year saw additional mergers and acquisitions, some of
which certainly aided in our performance. Most notable was
the announced take-over-bid for OSI Pharmaceuticals of New
York by the Japanese global pharmaceutical player, Astellas.
OSI Pharmaceuticals is a leader in oncology, a therapeutic class
that is deemed as a “must have” for pharmaceutical companies.
The bid was for nearly $3 billion, representing a 41% premium
to the company valuation prior to the acquisition offer.

Headwinds facing the major pharmaceutical companies are
reaching their zenith, with patent expirations and poor
product pipelines taking their toll. As a result, we expect
further acquisitions of biotechnology companies by
pharmaceutical companies.

We also expect a pause in major pharmaceutical company
mergers following the completion this year of two such
transactions, namely Pfizer/Wyeth and Merck/Schering-Plough. 

We anticipate that diversification plays will continue, however,
such as the Novartis takeover of Alcon. We suspect generic
drug manufactures could come into focus as acquisition
targets for major pharmaceutical companies.

O U R   S T R AT E G Y   F O R   2 0 1 0   A N D
B E YO N D

Looking ahead, we are optimistic about the prospects for
performance in the coming fiscal year. Low valuations across
sub-sectors and the strong earnings growth potential of our
holdings has historically been a rewarding combination. 

We will continue to be selective with regard to the
pharmaceutical sector, due to sector related challenges, and to
focus on companies with new products, earnings growth,
diversification of revenues, and attractive valuations. Healthy
dividend yields and acquisition potential are also potential
aspects for our investment theses in this area.

One area in which we have increased our exposure is generic
drug manufacturers. We think this sector is on a secular global
growth trajectory and we have thus made substantial strategic
investments in generic pharma companies in the U.S. and Asia.

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Review of Investments (continued)

09

We believe the Japanese generic drug market is in the nascent
stages and represents a compelling long term growth
investment opportunity.

With regard to biotechnology, we remain optimistic for the
major capitalisation companies. Following a difficult year,
valuations are near generational lows, despite excellent growth
potential and very limited patent exposure (unlike some of
their pharmaceutical company peers). For specialty companies,
we continue to favour those with novel product opportunities
for major unmet medical needs with near term regulatory and
commercial objectives. We are focused in areas such as
oncology, rheumatology, antivirals, and neuroscience. These
companies also are high probability targets for acquisitions.

Our geographic exposure continues to place significant
emphasis on our holdings in North America, with 70% of the
portfolio in that region. The balance of our exposure resides in
Europe (19%), Asia (8%) and Israel (3%).

Finally, we believe that the proposed change to the Company’s
investment policy, as described in the Chairman’s Statement
on page 3 of the Annual Report, will be of benefit to
shareholders and plays to OrbiMed’s strengths as we have
significant experience in these areas of the healthcare sector.

Samuel D Isaly
OrbiMed Capital LLC
Investment Manager
21 June 2010

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10

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Review of Investments (continued)

CO N T R I B U T I O N   BY   I N V E S T M E N T   –   E XC LU D I N G D E R I VAT I V E S

Top Five Contributors

Novartis 
Sinopharm
Dendreon (Including Dendreon 4.75% convertible bond)
Shire
Johnson & Johnson

Bottom Five Contributors

Biogen Idec
Genmab
Genzyme 
Gilead Science
GlaxoSmithKline

Contribution
for the year to
31 March 2010
£’000

Contribution
per share
(pence)*

6,504 
5,954 
5,003 
4,710 
3,897 

(2,744)
(2,117)
(1,885)
(1,270)
(1,095)

14.74 
13.49 
11.34 
10.67 
8.83 

59.07 

(6.22)
(4.80)
(4.27)
(2.88)
(2.48)

(20.65)

*

based on the weighted average number of shares in issue during the year ended 31 March 2010 (44,122,846).
Source: Frostrow Capital LLP

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Champions of Innovation

I N D U S T RY   L E A D I N G   I N V E S T M E N TS   I N  T H E P O R T F O L I O

11

1 )   B R I S TO L- M YE R S   S Q U I B B
Major pharmaceutical companies across the globe are all facing
the same problem – how to fill the new product gap. We
believe that Bristol-Myers is poised to do it best, with one of, if
not the strongest, pipelines in the industry. Perhaps the most
innovative of those compounds is ipilimumab, an antibody that
boosts one’s own immune system to treat cancer. The lead
indication is for the devastating disease of advanced melanoma
for which there are no approved treatments. We believe that
ipilimumab could be practically curative in some patients.
Perhaps the largest commercial opportunity for Bristol-Myers
lies with their cardiovascular drug, apixiban. This compound
belongs to a class of drugs called Factor Xa Inhibitors and we
believe this compound to be best-in-class with multi-billion
dollar sales potential. We expect these two compounds to enter
the market over the next two years.

3 )   D E N D R E O N   CO R P O R AT I O N
Dendreon is an emerging biotech company focused on cancer
therapies. The company’s lead product, Provenge, received U.S.
Food and Drug Administration (“FDA”) approval in April 2010
for the treatment of prostate cancer. Provenge is the first
cell-based immunotherapy, commonly referred to as a “cancer
vaccine”, to demonstrate efficacy against cancer. With this
therapy, a patient’s antigen presenting cells are harvested and
combined with an antigen found on prostate cancer cells and
then re-infused into the patient. This process “programmes”
the patient’s immune system to recognise and fight the
cancer. In a phase three trial released last year, prostate cancer
patients receiving Provenge lived four months longer than
those receiving placebo. We expect Provenge sales to
eventually exceed $2 billion annually. Dendreon is one of the
few late stage biotechnology companies launching a
blockbuster product, and as such, is a prime acquisition target
for big pharma.

2 )   A M G E N
Amgen is the world’s largest biotechnology company and
markets protein therapeutics in supportive cancer care,
nephrology, and inflammation. Its base business consists of its
Epogen/Aranesp franchise to treat anaemia, its
Neupogen/Neulasta franchise to treat low white blood cell
counts due to chemotherapy, and its drug Enbrel to treat
rheumatoid arthritis and psoriasis. The company’s anaemia
business has been under pressure over the past couple of years
due to safety concerns and reimbursement cutbacks, but we
believe the pressures on this business are now well-understood
by investors. The major growth driver for the company is a novel
antibody called Prolia, which is expected to be approved and
launched in 2010. Prolia has shown strong Phase three data for
preventing fractures in osteoporosis and cancer patients. The
company expects to announce additional Phase three results in
mid-2010 for the prevention of bone metastases. We believe
peak sales for this drug could approach $5 billion, making it one
of the largest biotech products to be launched in the near-term.

4)  HUMAN  GENOME  SCIENCES,  INC.
Human Genome Sciences (HGSI) is an emerging
biotechnology company developing drugs for autoimmune
disease, infectious disease and cancer. In 2009, the company
announced positive phase three clinical trial results for
Benlysta, a novel treatment for the inflammatory disorder
known as lupus. Benlysta is an antibody that targets the “BLyS”
protein and thus inhibits B-cell activity which is implicated in
lupus and other autoimmune diseases. Lupus has traditionally
been a very difficult disease to treat; there has not been a new
drug approved in the U.S. for lupus in over 50 years. With a
poorly-served market, we expect rapid uptake of Benlysta once
approved (around year-end). HGSI and GlaxoSmithKline (GSK)
are co-developing and commercializing Benlysta and therefore
HGSI would be a natural acquisition candidate for GSK to
obtain full rights to this potential blockbuster product.

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12

Portfolio

as at 31 March 2010

Investments
Johnson & Johnson 
Roche 
Pfizer
Novartis 
Merck 
Bristol-Myers Squibb
Shire #
Amgen 
Teva Pharmaceutical Industries
Genzyme 
Top 10 investments
Dendreon ^
Celgene 
Mylan
Sinopharm 
Abbott Laboratories
Perrigo 
Sawai Pharmaceutical 
Hospira 
Elan ~
Towa Pharmaceutical 
Top 20 investments
Vertex Pharmaceuticals 
Gilead Sciences 
Vertex Milestone Monetization (unquoted, CPEC)† 
Illumina 
Cubist Pharmaceuticals 
Nichi-Iko Pharmaceutical 
Allergan 
Endo Pharmaceuticals 
NPS Pharmaceuticals 
Allos Therapeutics
Top 30 investments
BioMarin Pharmaceutical 
Incyte 4.75% 01/10/2015
Intermune
Warner Chilcott 
VWR Funding 10.25% 15/07/2015
Momenta Pharmaceuticals 
OSI Pharmaceuticals
Angiotech Pharmaceuticals FRN 01/12/2013
Pharma 10 Cinacalcet Royalty 15.5% 30/03/2017
QHP Royalty 10.25% 15/03/2015
Top 40 investments
Salix Pharmaceuticals 5.5% 15/08/2028
Medicines 
Endo Pharmaceutical 1.75% 15/04/2015
Genmab 
Genomic Health 
Total investments (excluding options)
Options
Johnson & Johnson >*
Celgene >
SPDR *
Myriad Genetics *
Pfizer >*
Merck >
Total options
Total investments including options 

Country
USA
Switzerland
USA
Switzerland
USA 
USA
UK
USA
Israel
USA

USA
USA
USA
China
USA
USA
Japan
USA
Ireland
Japan

USA
USA
USA
USA
USA
Japan
USA
USA
USA
USA

USA
USA
USA
Ireland
USA
USA
USA
USA
USA
USA

USA
USA
USA
Denmark
USA

USA
USA
USA
USA
USA
USA

Market value
£’000
26,653
26,487
19,484
19,244
18,452
17,954
14,110
10,834
10,814
10,592
174,624
10,512
10,202
10,035
9,602
8,228
8,207
8,177
8,065
7,776
7,220
262,648
7,406
7,376
7,314
7,005
6,951
6,950
6,739
6,430
6,122
6,033
330,974
5,919
5,854
5,275
5,215
4,635
4,293
3,864
3,204
2,983
2,564
374,780
2,690
2,331
1,644
1,324
830
383,599

292
274
135
(5)
(10)
(58)
628
384,227

As at 31 March 2010 the U.S.$/£ exchange rate was U.S.$1.5169/£1.00 (31 March 2009: U.S $1.4334/£1.00).
#
includes Shire 2.75% 09/05/2014 equating to 0.4% of investments.
^
includes Dendreon 4.75% 15/06/2014 equating to 1.0% of investments.
~
includes Elan 8.75% 15/10/2016 equating to 0.7% of investments. 
>
includes Call Options.
* 
includes Put Options.
†
Convertible Preferred Equity Certificates (CPEC).

% of
investments
6.9
6.9
5.1
5.0
4.8
4.7
3.7
2.8
2.8
2.8
45.5 
2.7
2.7
2.6
2.5
2.1
2.1
2.1
2.1
2.0
1.9
68.3
1.9
1.9
1.9
1.8
1.8
1.8
1.8
1.7
1.6
1.6
86.1
1.5
1.5
1.4
1.4
1.2
1.1
1.0
0.8
0.8
0.7
97.5
0.7
0.6
0.4
0.3
0.3
99.8

0.1
0.1
-
-
-
-
0.2
100.0

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Analysis of the Portfolio

13

T H E   P O R T F O L I O
as at 31 March 2010

Equities (including options)
Convertibles
Fixed Interest Securities

Total of all investments

G E O G R A P H I C A L   A N A LYS I S
as at 31 March

2 0 1 0

Market value
£’000

% of 
investments

91.8
4.7
3.5

100.0

352,442
18,399
13,386

384,227

2 0 0 9

Europe 19%

Europe 28%

USA
70%

Far East 
incl. Japan
8%
Israel
3%

USA
64%

Far East 
incl. Japan
8%

A N A LYS I S   BY   MA R K E T   C A P I TA L I S AT I O N
as at 31 March

2 0 1 0

Large Cap 
Israel 3%

Large Cap 
Far East incl. 
Japan 8%

2 0 0 9

Large Cap 
Far East incl. 
Japan 8%

Small Cap 
USA 32%

Small Cap 
Europe 2%

Large Cap 
Europe 17%

Small Cap USA
34%

Large Cap 
Europe 16%

Large Cap USA
38%

Small Cap 
Europe 12%

Large Cap USA
30%

Note:
A small capitalisation company is defined as being one with a market capitalisation of less than U.S.$5bn and a large capitalisation
company is one with a market capitalisation of more than U.S.$5bn.

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14

Report of the Directors
Incorporating the Business Review

The Directors present their report and the audited financial
statements for the year ended 31 March 2010.

S TAT U S   A N D   AC T I V I T I E S   O F  T H E   CO M PA NY
During the year under review the Company has continued to
conduct its affairs so as to qualify as an investment company, as
defined under s833 of the Companies Act 2006, and an
investment trust within the meaning of s842 of the Income &
Corporation Taxes Act 1988. HM Revenue & Customs approval
of the Company’s status as an investment trust has been
received for all years up to and including the year ended
31 March 2009. This is, however, subject to review should there
be any enquiry under Corporation Tax Self Assessment. The
Directors are of the opinion that the Company has
subsequently directed its affairs so as to enable it to continue to
obtain HM Revenue & Customs approval as an investment trust.

The Company’s shares are eligible for inclusion in the stocks
and shares component of an Individual Savings Account.

CO N T I N UAT I O N   O F  T H E   CO M PA NY
A resolution was passed at last year’s Annual General Meeting
that the Company continue as an investment trust for a further
five year period. In accordance with the Company’s Articles of
Association, shareholders will have an opportunity to vote on
the continuation of the Company at the Annual General
Meeting in 2014 and every five years thereafter.

I N V E S T M E N T   O B J E C T I V E   A N D   B E N C H MA R K
The Company invests worldwide in pharmaceutical,
biotechnology and related companies in the healthcare sector
with the objective of achieving a high level of capital growth.
Performance is measured against the Datastream World
Pharmaceutical and Biotechnology Index (total return, sterling
adjusted).

I N V E S T M E N T   P O L I C Y
In order to achieve its investment objective, the Company
invests in a diversified portfolio of shares in pharmaceutical,
biotechnology and related companies in the healthcare sector
with the objective of achieving a high level of capital growth. It
uses gearing and derivative transactions to mitigate risk and
also to enhance capital returns. 

Investment Limitations and Guidelines
The Board seeks to manage the Company’s risk by imposing
various investment limits and restrictions:

•

•

•

•

•

•

•

•

•

The Company will not invest more than 10% of its gross
assets in other listed investment companies (including
listed investment trusts);

The Company will not invest more than 15% of the
portfolio in any one individual stock at the time of
acquisition;

At least 60% of the portfolio will normally be invested in
larger companies (i.e. with a market capitalisation of at
least US$5bn);

At least 20% of the portfolio will normally be invested in
smaller companies (i.e. with a market capitalisation of less
than US$5bn);

Investment in unquoted securities will not exceed 10% of
the portfolio at the time of acquisition;

A maximum of 5% of the portfolio, at the time of
acquisition, may be invested in each of debt instruments,
convertibles and royalty bonds issued by pharmaceutical
and biotechnology companies;

The Company’s gearing policy is to borrow up to the lower
of £70m or 20% of the Company’s net asset value;

Derivative transactions can be used to mitigate risk and/or
enhance capital returns and will be restricted to 5% of the
portfolio; and

Equity Swaps may be used in order to meet the Company’s
investment objective of achieving a high level of capital
growth and is restricted to 5% of the portfolio.

Compliance with the Board’s investment limitations and
guidelines is monitored continuously by Frostrow Capital LLP
(“Frostrow” or the “Manager”) and OrbiMed Capital LLC
(“OrbiMed” or the “Investment Manager”) and is reported to the
Board on a monthly basis.

P E R F O R MA N C E
In the year to 31 March 2010, the Company’s diluted net asset
value per share increased by 25.3% compared to a rise of
24.6% in the Datastream World Pharmaceutical and
Biotechnology Index (total return, sterling adjusted). The
Company’s share price rose by 27.4% in the same period.

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Report of the Directors (continued)
Incorporating the Business Review

15

The Review of Investments on pages 7 to 10 includes a review
of the principal developments during the year, together with
information on investment activity within the
Company’s portfolio.

R E S U LTS   A N D   D I V I D E N D S
The results attributable to shareholders for the year and the
transfer to reserves are shown on page 36. In order to maintain
investment trust status the Directors have declared an interim
dividend for the year of 8.5p per share (2009: interim dividend of
5.0p) payable on 26 July 2010.

K E Y   P E R F O R MA N C E   I N D I C ATO R S   ( ‘ K P I s ’ )
At each Board meeting the Board assesses the Company’s
performance in meeting its investment objective and against
the following key performance indicators:

•

•

•

•

•

•

•

Net asset value total return (see page 1)

Share price total return (see pages 1 and 33)

Stock contribution analysis (see page 10)

Share price premium/discount to net asset value per share
(see page 1)

Total expense ratio (see page 1)

Benchmark and peer group performance (see pages 1 and 33)

Issue of new shares/repurchase of own shares (see pages 16
and 17)

The management of the portfolio is conducted by the
Investment Manager and the management of the Company’s
affairs, including marketing, administration and company
secretarial matters is conducted by the Manager. Each provider
is responsible to the Board which is ultimately responsible to
the shareholders for performing against, inter alia, the above
KPIs within the terms of their respective agreements by
utilising the capabilities of the experienced professionals
within each firm.

P R I N C I PA L   R I S K S   A N D  T H E I R   M I T I G AT I O N
The Company’s assets consist principally of listed equities; its
main area of risk is therefore stockmarket-related. The specific
key risks faced by the Company, together with the Board’s
mitigation approach, are as follows:

Objective and Strategy – The Company and its investment
objective become unattractive to investors
The Board regularly reviews the investment mandate and the
long-term investment strategy in relation to market and
economic conditions, and the operation of the Company’s peers,
thereby monitoring whether the Company should continue in its
present form. A continuation vote was held at last year’s Annual
General Meeting and will be held every five years thereafter. Each
month the Board receives a monthly review, which monitors the
Company’s investment performance (both on an absolute basis
and against the benchmark and peer group) and its compliance
with the investment guidelines. Additional reports and
presentations are regularly presented to investors by the
Company’s Manager, Investment Manager and Corporate
Stockbroker.

Level of discount/premium – Share price performance lags
NAV performance
The Board undertakes a regular review of the level of
discount/premium and consideration is given to ways in which
share price performance may be enhanced, including the
effectiveness of marketing and share buy-backs, where
appropriate. The Board has implemented a discount control
mechanism intended to establish a maximum level of 6%
discount of share price to the diluted net asset value per share.
Shareholders should note that it remains possible for the share
price discount to net asset value per share to be greater than
6% on any one day and is due to the fact that the share price
continues to be influenced by overall supply and demand for
the Company’s shares in the secondary market. The average
month end share price discount during the year was 7.1%, a
level that has been broadly maintained since the year end. The
making and timing of any share buy-backs is at the absolute
discretion of the Board.

Market Price and Industry Risk
Market price risk arises mainly from uncertainty about future
prices of financial instruments held. It represents the potential
loss the Company might suffer through holding market
positions in the face of price movements. 

Industry risk exists in all specialist industries. Risks are inherent
in pharmaceutical companies with, for example, the potential
for drug withdrawals from the market or failures after launch
and lack of expected profit growth.

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Report of the Directors (continued)
Incorporating the Business Review

The Board meets on a quarterly basis during the year and on
an ad hoc basis if necessary. At each meeting they consider
the asset allocation of the portfolio. The Investment Manager
has responsibility for selecting investments in accordance with
the Company’s investment objective and seeks to ensure that
individual stocks meet an acceptable risk-reward profile. 

Liquidity Risk
The Company’s assets comprise mainly realisable securities,
which can be sold to meet funding requirements if necessary.

Portfolio Performance and Financial Instruments –
Investment performance may not be meeting the
Investment objective or shareholder requirements
The Board regularly reviews investment performance against the
benchmark and against peer group. The Board also receives
regular reports that show an analysis of performance compared
with other relevant indices. The Investment Manager provides
an explanation of stock selection decisions and an overall
rationale for the make-up of the portfolio. The Investment
Manager discusses current and potential investment holdings
with the Board on a regular basis in addition to new initiatives,
which may enhance shareholder returns.

Operational and Regulatory – Compliance with s1158 of
the Corporation Taxes Act 2010 (formerly s842 of the
Income and Corporation Taxes Act 1988)
A breach of s1158 of the Corporation Taxes Act 2010 could lead
to the Company being subject to capital gains tax on the sale of
its investments, whilst serious breach of other regulatory rules
may lead to suspension from the Stock Exchange or to a
qualified Audit Report. Other control failures, either by the
Manager, the Investment Manager or any other of the
Company’s service providers, may result in operational and/or
reputational problems, erroneous disclosures or loss of assets
through fraud, as well as breaches of regulations.

The Manager reviews the level of compliance with s1158 and
other financial regulatory requirements on a daily basis. All
investment transactions and income and expenditure forecasts
are reported to the Board. The Board regularly considers all risks,
the measures in place to control them and the possibility of any
other risks that could arise. The Board ensures that satisfactory
assurances are received from service providers. The Compliance
Officer of the Manager and the Investment Manager produce
regular reports for review by the Company’s Audit Committee
and are available to attend meetings in person if required.

Currency Risk
A significant proportion of the Company’s assets are, and will
continue to be, invested in securities denominated in foreign
currencies, in particular U.S. dollars. As the Company’s shares
are denominated and traded in sterling, the return to
shareholders will be affected by changes in the value of
sterling relative to those foreign currencies. The Board has
made clear the Company’s position with regard to currency
fluctuation, which is that it does not currently hedge against
currency exposure.

Loan Facility Risk – The provider of the Company’s loan
facility may no longer be prepared to lend to the
Company

The Board and the Investment Manager are kept fully informed
of any likelihood of the withdrawal of the loan facility so that
repayment can be effected in an orderly fashion.

Credit Risk

The Company’s assets can be held by Goldman Sachs & Co.
New York as collateral for the loan provided by them to the
Company. Such assets taken as collateral may be used, loaned,
sold, rehypothecated or transferred by Goldman Sachs & Co.
New York, although the Company maintains the economic
benefits from ownership of those assets. Goldman Sachs & Co.
New York may take up to 140% of the value of the outstanding
loan as collateral. The Company is fully protected, such
protection being equal to the net assets held by Goldman
Sachs & Co. New York, by SEC rules and U.S. legislation.

Assets held by Goldman Sachs & Co. New York, as custodian,
that are not used as collateral, are held in segregated client
accounts. (Also see Glossary on page 62).

Further information on financial instruments and risk, as
required by FRS 29, can be found in note 18 to the financial
statements beginning on page 49.

LOA N   FAC I L I T Y
The Company’s borrowing requirements are met through the
utilisation of a loan facility, repayable on demand, provided by
Goldman Sachs & Co. New York.

S H A R E   C A P I TA L
The final exercise date for the Company’s warrants was 31 July
2009 and all of the remaining warrants in issue on that date
were converted into shares. As a result, 10,745,610 shares were

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Report of the Directors (continued)
Incorporating the Business Review

17

allotted by the Company on 5 August 2009, raising £49.9m of
additional funds for the Company. On 4 September 2009, the
Company made a bonus issue of subscription shares on the
basis of one subscription share for every five ordinary shares
held at that date. The subscription shares have quarterly
subscription dates and the following shares were allotted by
the Company as a result of holders of the subscription shares
exercising their subscription rights during the year:
42,148 shares were allotted on 13 November 2009 raising
£259,000. 696,505 shares were allotted on 3 February 2010
raising £4.3m.

Subsequent to the year-end, 280,794 shares were allotted on
7 May 2010 raising £1.7m.

At the Annual General Meeting held on 17 July 2009, authority
was granted for the repurchase of 5,898,027 shares of 25p,
representing 14.99% of the issued share capital at that time. This
authority was renewed by the Company at a General Meeting
held on 2 March 2010 where authority was granted to
repurchase 6,716,138 shares of 25p, representing 14.99% of the
issued share capital at that time. In the year under review, the
Company bought back a total of 8,508,938 shares, 6,239,416 of
which were held in treasury at 31 March 2010, at a cost of
£48,453,000 (including expenses). Since the year end and to
21 June 2010, a further 1,637,733 shares, costing £10,905,000
(including expenses), have been repurchased and held in
treasury. In aggregate, to 21 June 2010, the shares bought back
equate to a total of 24.5% of the issued share capital at the
beginning of the year. As indicated in the Chairman’s Statement,
the Board has agreed that any treasury shares remaining on
15 July 2010, the date of the Annual General Meeting, will be
cancelled. A total of 3,985,397 shares held in treasury were
cancelled on 20 July 2009.

P R O S P E C TS

Following a general and developing recovery in global markets, the
Company’s Investment Manager believes strongly that the sector
will benefit from the removal of uncertainty surrounding healthcare
reform in the U.S. In addition, a combination of low valuations and
strong earnings growth potential together with continued merger
and acquisition activity and a number of expected high profile
product approvals will all be key drivers for future performance.

The Association of Investment Companies continues to work
towards ensuring that the AIFM Directive is drafted to

accommodate the UK investment company structure. The Board
will continue to keep this situation under close review.

Further information on the Company’s performance can be
found in the Review of Investments provided by the
Company’s Investment Manager, that begins on page 7.

MA N AG E M E N T
Management, Administrative and Secretarial Services Agreement:
Management, Administrative, Secretarial and other services are
provided to the Company by the Manager. The Manager is
authorised and regulated by the Financial Services Authority. 

Frostrow Capital LLP, as Manager, receives a periodic fee equal
to 0.30% per annum of the Company’s market capitalisation up
to £150m and 0.20% per annum of the market capitalisation in
excess of £150m, plus a fixed amount equal to £50,000
per annum.

The notice period on the Management, Administration and
Company Secretarial Agreement with Frostrow is 12 months,
termination can be initiated by either party.

The Manager, under the terms of the agreement provides, inter
alia, the following services:

• marketing and shareholder services;

•

•

administrative services;

advice and guidance in respect of corporate governance
requirements;

• maintaining the books of account and record in respect of
Company dealing, investments, transactions, dividends and
other income, the income account, balance sheet and cash
books and statements;

•

•

preparation and despatch of the audited annual and
unaudited interim report and accounts and interim
management statements; and

attending to general tax affairs where necessary.

I N V E S T M E N T   MA N AG E M E N T  
Investment Management Agreement:
Investment Management Services are provided by the
Investment Manager. The Investment Manager is authorised
and regulated by the U.S. Securities and Exchange
Commission. The Investment Manager receives a periodic fee
equal to 0.65% p.a. of the Company’s net asset value. The
Investment Management Agreement may be terminated by

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Report of the Directors (continued)
Incorporating the Business Review

either party giving notice of not less than 12 months. The
Investment Manager under the terms of the agreement
provides, inter alia, the following services:

•

•

•

•

•

seeking out and evaluating investment opportunities;

recommending the manner by which monies should be
invested, disinvested, retained or realised;

advising on how rights conferred by the investments
should be exercised;

analysing the performance of investments made; and

advising the Company in relation to trends, market
movements and other matters which may affect the
investment policy of the Company.

Performance Fee:
Dependent on the level of performance achieved, the
Manager and Investment Manager are also entitled to the
payment of a performance fee. The performance fee is
calculated by reference to the amount by which the
Company’s portfolio has out-performed the Datastream World
Pharmaceutical and Biotechnology Index (total return, sterling
adjusted) (the “Benchmark”).

The fee is calculated quarterly by comparing the cumulative
performance of the Company’s portfolio with the cumulative
performance of the Benchmark since the launch of the
Company in 1995. The performance fee amounts to 16.5% of
any outperformance of the net asset value over the
Benchmark, the Investment Manager receiving 15.0% and the
Manager receiving 1.5% of the outperformance.

At each quarterly calculation date any performance fee
payable is based on the lower of:

(i)

(ii)

the cumulative outperformance of the portfolio over the
Benchmark as at the quarter end date; and

the cumulative out-performance of the portfolio over the
Benchmark as at the corresponding quarter end date in
the previous year.

In the year under review no performance fee was paid.
However, a performance fee of £2,983,000 was accrued as at
31 March 2010 (see note 3 on page 42) and the accrual at 
31 March 2009 crystallised and became payable post year 
end.

CO N T I N U I N G   A P P O I N T M E N T   O F  T H E
MA N AG E R   A N D   I N V E S T M E N T   MA N AG E R
The Board has concluded that it is in shareholders’ interests
that the Manager and the Investment Manager continue in
their roles. The review undertaken by the Board considered the
Company’s investment performance over both the short and
longer terms, together with the quality and adequacy of other
services provided. The Board also reviewed the
appropriateness of the terms of the Investment Management
and Management Agreements, in particular the length of
notice period and the fee structures.

G O I N G   CO N C E R N
The Company’s business activities together with the factors likely
to affect its future development, performance and position are set
out in the Report of the Directors on pages 14 to 24. The financial
position of the Company, its liquidity position and its borrowing
facility are set out in the notes to the financial statements
beginning on page 40. In addition, the Corporate Governance
Report, the Financial Statements and the associated notes give
details of the Company’s objectives, policies and processes, its
financial risk management objectives and its exposure to risks. The
Company has considerable financial resources and a good spread
of investments across different geographical areas. The majority of
the Company’s investments are listed on stock exchanges and are
readily realisable. Having considered the Company’s prospects, the
Directors believe that it is appropriate to adopt the going concern
basis in preparing the financial statements as the assets of the
Company consist mainly of securities that are readily realisable and,
accordingly, the Company has adequate financial resources to
continue in operational existence for the foreseeable future.

C R E D I TO R S PAYM E N T   P O L I C Y
Terms of payment are negotiated with suppliers when
agreeing settlement details for transactions. While the
Company does not follow a formal code, it is the Company’s
continuing policy to pay amounts due to creditors as and
when they become due. As at 31 March 2010, the Company
did not have any trade creditors (2009: Nil).

C H A R I TA B L E   A N D   P O L I T I C A L   D O N AT I O N S
The Company has not in the past and does not intend in
future to make any charitable or political donations.

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Report of the Directors (continued)
Incorporating the Business Review

19

E N V I R O N M E N TA L   A N D   E T H I C A L   P O L I C Y
The Company’s primary objective is to achieve a high level of
capital growth by investment in pharmaceutical and
biotechnology companies and the Board recognises that this
should be done in an environmentally responsible way. The
Directors support the action being taken by the major
pharmaceutical companies to make products more affordable
to patients in developing countries. The Directors believe that
the Company would be in breach of its fiduciary duties to
shareholders if investment decisions were based solely on
ethical or environmental considerations.

D I R E C TO R S’ I N T E R E S TS

D I R E C TO R S
The Directors of the Company, who served throughout the
year, are all non-executive and are listed below. Their
biographies can be found on pages 4 and 5.

Martin Smith (Chairman)
Josephine Dixon
Paul Gaunt
Professor Duncan Geddes
Dr David Holbrook 
Samuel D Isaly
Anthony Townsend

The beneficial interests of the Directors and their families in the Company were as set out below:

Martin Smith
Josephine Dixon
Paul Gaunt
Professor Duncan Geddes
Dr David Holbrook
Samuel D Isaly
Anthony Townsend

Shares
of 25p each

31 March 2010

1 April 2009

Warrants to subscribe
for Shares/Subscription Shares*
1 April 2009

31 March 2010

2,000
3,000
–
42,250
–
353,600
18,785

–
–
–
38,250
–
235,673
17,370

400
600
–
8,450
–
100,720
3,757

–
25,680
–
4,000
–
407,134
1,415

*
The warrants to subscribe for ordinary shares expired on 31 July 2009. The subscription shares were issued on 4 September 2009.

As at 21 June 2010 there had been no changes in the above details.

Samuel D Isaly is a partner in OrbiMed Capital LLC which is party to the Investment Management Agreement with the Company
and receives fees as described on pages 17 and 18. A number of the partners at OrbiMed Capital LLC have a minority financial
interest totalling 20% in Frostrow Capital LLP, the Company’s Manager.

D I R E C TO R S’ F E E S  
A report on Directors’Remuneration is set out on pages 32 and 33.

D I R E C TO R S’ &   O F F I C E R S’ L I A B I L I T Y
I N S U R A N C E   CO V E R
Directors’ & officers’ liability insurance cover was maintained by
the Board during the year ended 31 March 2010. It is intended
that this policy will continue for the year ending 31 March
2011 and subsequent years.

D I R E C TO R S’ I N D E M N I T I E S  
As at the date of this report, indemnities are in force between the
Company and each of its Directors under which the Company

has agreed to indemnify each Director, to the extent permitted
by law, in respect of certain liabilities incurred as a result of
carrying out his role as a Director of the Company. The Directors
are also indemnified against the costs of defending any criminal
or civil proceedings or any claim by the Company or a regulator
as they are incurred provided that where the defence is
unsuccessful the Director must repay those defence costs to the
Company. The indemnities are qualifying third party indemnity
provisions for the purposes of the Companies Act 2006.

A copy of each deed of indemnity is available for inspection at
the Company’s registered office during normal business hours
and will be available for inspection at the Annual General
Meeting.

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Report of the Directors (continued)
Incorporating the Business Review

S U B S TA N T I A L   S H A R E H O L D I N G S
As at 30 April 2010 the Company was aware of the following interests in the shares of the Company, which exceeded 3% of the
issued share capital (excluding treasury shares):

Beneficial
shareholder

East Riding of Yorkshire Council
Newton Investment Management
Rensburg Sheppards Investment Management
Alliance Trust Savings
Legal & General Investment Management
Smith & Williamson
Investec Asset Management
Deutsche Bank Private Wealth Management

Registered holder

Nortrust Nominees
Various Nominees
Ferlim Nominees/Hero Nominees
Alliance Trust Savings Nominees
Various Nominees
Various Nominees
Various Nominees
Pershing Nominees

Number of
shares

4,723,495
3,512,919
2,800,225
2,003,705
1,772,830
1,562,728
1,500,974
1,356,978

% of issued
share capital

10.65
7.92
6.32
4.52
4.00
3.52
3.39
3.06

I N D E P E N D E N T   AU D I TO R S
Ernst & Young LLP have indicated their willingness to continue
to act as Auditors to the Company and a resolution for their
re-appointment, will be proposed at the forthcoming Annual
General Meeting.

AU D I T   I N F O R MAT I O N
The Directors who held office at the date of approval of this
Directors’ Report confirm that, so far as they are aware, there is
no relevant audit information of which the Auditors are
unaware; and that each Director has taken all steps they ought
to have taken as a Director to make themselves aware of any
relevant audit information and to establish that the auditors
are aware of such information.

S E C T I O N   9 9 2   O F  T H E   CO M PA N I E S   AC T   2 0 0 6
The following disclosures are made in accordance with Section
992 of the Companies Act 2006.

Capital Structure
The Company’s capital structure is summarised in note 13 on
page 47.

Voting Rights in the Company’s shares
Details of the voting rights in the Company’s shares at the date
of this Annual Report are given in note 9 to the Notice of
Annual General Meeting on page 59.

CO R P O R AT E   G O V E R N A N C E
A formal statement on Corporate Governance, which forms
part of this Report of the Directors, is set out on pages 26
to 31.

B E N E F I C I A L   O W N E R S   O F   S H A R E S   –
I N F O R MAT I O N   R I G H TS
Beneficial owners of shares who have been nominated by the
registered holder of those shares to receive information rights
under section 146 of the Companies Act 2006 are required to
direct all communications to the registered holder of their
shares rather than to the Company’s registrar, Capita Registrars,
or to the Company directly.

N OT I C E   P E R I O D   F O R   G E N E R A L   M E E T I N G S
Recent amendments made to the Company’s Articles of
Association included a provision allowing general meetings of
the Company to be called on the minimum notice period
provided for in the Companies Act 2006. For meetings other
than Annual General Meetings this is currently a period of 14
clear days.

A Special Resolution was passed by shareholders at last year’s
Annual General Meeting approving this. The Board is
proposing Resolution 14 as a Special Resolution to renew this
approval for a further year. The notice period for Annual
General Meetings will remain 21 clear days.

E L E C T R O N I C   CO M M U N I C AT I O N S
Included with notice of the Annual General Meeting is a letter
to shareholders asking for their individual consent to receive
documents, notices and information either electronically or via
the Company’s website. Ordinary Resolution 13 also requests
the consent of shareholders to send or supply documents by
electronic means.

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Report of the Directors (continued)
Incorporating the Business Review

21

Ordinary Resolution 13 and your individual consent will give
the Company more flexibility to supply notices, documents or
information in electronic form and by means of a website
pursuant to the FSA’s Disclosure Rules and Transparency Rules.
The Company’s Articles of Association were updated at last
year’s Annual General Meeting to enable the Company to send
all documents and notices electronically rather than just
notices of meetings, proxies, and copies of annual reports and
accounts and summary financial statements and to permit the
Company to send documents by means of a website and to
ensure the Articles of Association are consistent with the
provisions of the Companies Act 2006.

Shareholders should note that even if Ordinary Resolution 13 is
passed no action will be taken and no documents will be sent
electronically until the consent of shareholders in General
Meeting has been obtained and until the Company receives
individual consent to electronic communication. However,
provided that Ordinary Resolution 13 is passed at the Annual
General Meeting and provided we have not received a
response from you by 23 July 2010, the Companies Act 2006
allows us to assume that you have agreed that the documents
and information referred to in the consent letter can be sent to
you by posting them on the Company’s website.

A shareholder may, if he or she wishes, continue to receive all
company communications in hard copy form. Moreover, a
shareholder may, in relation to a particular communication,
request a hard copy form of that communication or, at any
time, revoke his or her general agreement to be provided
documentation in electronic form or by means of a website by
delivering written notice or such revocation to the Company.

P R O P O S E D   C H A N G E  TO   I N V E S T M E N T   P O L I C Y

The Company’s current investment policy is to invest
worldwide in pharmaceutical, biotechnology and related
companies in the healthcare sector with the objective of
achieving a high level of capital growth. However, the
Company’s Investment manager believes that it would be
beneficial to shareholders to broaden the definition of the
healthcare sector as referred to within the investment policy, to
include companies in the healthcare equipment and
healthcare technology sectors and also to include companies
that provide healthcare and related services. None of these
areas of the healthcare sector would individually represent

more than 15% of the portfolio at the date of acquisition and
any investment made would be subject to the Company’s
existing limitations and guidelines.

As a consequence of this development, the Board is also
proposing a change from the Company’s existing benchmark
index which is the Datastream World Pharmaceutical and
Biotechnology Index (measured in sterling terms on a total
return basis), to the MSCI World Healthcare Index (measured in
sterling terms on a total return basis) as it is believed that this
index will more accurately reflect the makeup of the
Company’s portfolio. The MSCI World Healthcare Index, as
described above, will be used in relation to the calculation of
any performance fee to be paid to the Investment Manager
and Manager.

Under the Listing Rules the Company is required to seek the
approval of shareholders for any material change in its
investment policy and any related party transaction, such as
the change to the Company’s benchmark in relation to the
calculation of any future performance fee. Therefore an
ordinary resolution to approve the above-mentioned changes
to the Company’s investment policy and benchmark will be
proposed at the Company’s forthcoming Annual General
Meeting. As required for a related party transaction of this
nature, the Manager, Investment Manager and their associates
will not be entitled to vote on this resolution.

The Manager, Investment Manager and their associates have
not participated in the Board’s consideration of the change to
the Company's benchmark for the purposes of determining
whether it is fair and reasonable as far as the holders of the
Company’s ordinary and subscription shares are concerned.

The Board strongly supports the investment philosophy and
approach of the Company’s Investment Manager and is of the
view that these changes will be of benefit to shareholders.

Full details of the Company’s current investment policy are set
out on page 14. The proposed revised investment policy is set
out below.

I N V E S T M E N T   P O L I C Y
In order to achieve its investment objective, the Company
invests worldwide in a diversified portfolio of shares in
pharmaceutical, biotechnology and related companies in the
healthcare sector with the objective of achieving a high level

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Report of the Directors (continued)
Incorporating the Business Review

of capital growth. It uses gearing and derivative transactions to
mitigate risk and also to enhance capital returns. 

•

•

•

•

•

•

•

•

•

•

The Company will not invest more than 10% of its gross
assets in other listed investment companies (including
listed investment trusts);

The Company will not invest more than 15% of the
portfolio in any one individual stock at the time of
acquisition;

At least 60% of the portfolio will normally be invested in
larger companies (i.e. with a market capitalisation of at
least US$5bn);

At least 20% of the portfolio will normally be invested in
smaller companies (i.e. with a market capitalisation of less
than US$5bn);

Investment in unquoted securities will not exceed 10% of
the portfolio at the time of acquisition;

A maximum of 5% of the portfolio, at the time of
acquisition, may be invested in each of debt instruments,
convertibles and royalty bonds issued by pharmaceutical
and biotechnology companies;

A maximum of 15% of the portfolio, at the time of
acquisition, may be invested in companies in each of the
following sectors:

healthcare equipment
healthcare technology

–
–
– providers of healthcare and related services

The Company’s gearing policy is to borrow up to the lower
of £70m or 20% of the Company’s net asset value;

Derivative transactions can be used to mitigate risk or
enhance capital returns and will be restricted to 5% of the
portfolio; and

Equity Swaps may be used in order to meet the Company’s
investment objective of achieving a high level of capital
growth and is restricted to 5% of the portfolio.

PROPOSED CHANGE TO THE COMPANY’S NAME
As a consequence of the proposals to amend the Company’s
investment policy a Special Resolution will be proposed at the
Annual General Meeting to change the Company’s name to
the Worldwide Healthcare Trust PLC.

PERFORMANCE FEE
As a consequence of the proposed change to the Company’s
benchmark, shareholders should note that the Company’s
performance fee, described on page 18 will be amended to
substitute the MSCI World Healthcare Index (measured in
sterling terms on a total return basis) for the Company’s
current benchmark. Shareholders should further note that the
Company’s performance fee is not capped and the proposed
change of benchmark could potentially result in a
performance fee being paid where none or a lesser amount
would be paid under current arrangements. Likewise, under
the proposed change of benchmark, the situation could arise
where no performance fee is paid where one would be
payable under the current arrangements. No change to the
quantum of the performance fee is proposed.

A N N UA L   G E N E R A L   M E E T I N G
The formal Notice of Annual General Meeting is set out on
pages 56 to 60 of this Annual Report.

Resolutions relating to the following items of special business
will be proposed at the forthcoming Annual General Meeting:

Issue of Shares
Ordinary Resolution 9 in the Notice of Annual General Meeting
gives authority to the Directors to allot the unissued share capital
up to an aggregate nominal amount of £1,074,495 (equivalent to
4,297,982 shares, or 10% of the Company’s existing issued share
capital on 21 June 2010, being the nearest practicable date prior
to the signing of this Report). Such authority will expire on the
date of the next Annual General Meeting or after a period of
15 months from the date of the passing of the resolution,
whichever is earlier. This means that the authority will have to be
renewed at the next Annual General Meeting.

When shares are to be allotted for cash, Section 551 of the
Companies Act 2006 (the “Act”) provides that existing
shareholders have pre-emption rights and that the new shares
must be offered first to such shareholders in proportion to
their existing holding of shares. However, shareholders can, by
special resolution, authorise the Directors to allot shares
otherwise than by a pro rata issue to existing shareholders.
Special Resolution 10 will, if passed, give the Directors power
to allot for cash equity securities up to 10% of the Company’s
existing share capital on 21 June 2010 (reduced by any

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Report of the Directors (continued)
Incorporating the Business Review

23

treasury shares sold by the Company pursuant to Special
Resolution 11, as described below), as if Section 551 of the Act
does not apply. This is the same nominal amount of share
capital which the Directors are seeking the authority to allot
pursuant to Resolution 9. This authority will also expire on the
date of the next Annual General Meeting or after a period of
15 months, whichever is earlier. This authority will not be used
in connection with a rights issue by the Company.

Under the Companies (Acquisition of Own Shares) (Treasury
Shares) Regulations 2003 (as amended) (the “Treasury Share
Regulations”) the Company is permitted to buy back and hold
shares in treasury and then sell them at a later date for cash,
rather than cancelling them. The Treasury Share Regulations
require such sale to be on a pre-emptive, pro rata, basis to
existing shareholders unless shareholders agree by special
resolution to disapply such pre-emption rights. Accordingly, in
addition to giving the Directors power to allot unissued share
capital on a non pre-emptive basis pursuant to Resolution 10,
Resolution 11, if passed, will give the Directors authority to sell
shares held in treasury on a non pre-emptive basis. No dividends
may be paid on any shares held in treasury and no voting rights
will attach to such shares. The benefit of the ability to hold
treasury shares is that such shares may be resold. This should
give the Company greater flexibility in managing its share
capital, and improve liquidity in its shares. It is the intention of
the Board that any re-sale of treasury shares would only take
place at a narrower discount to the net asset value per share
than that at which they had been bought into treasury, and in
any event at a discount no greater than 5% to the prevailing net
asset value per share, and this is reflected in the text of
Resolution 11. It is also the intention of the Board that sales from
treasury would only take place when the Board believes that to
do so would assist in the provision of liquidity to the market. The
number of treasury shares which may be sold pursuant to this
authority is limited to 10% of the Company’s existing share
capital on 21 June 2010 (reduced by any equity securities
allotted for cash on a non-pro rata basis pursuant to Resolution
10, as described above). This authority will also expire on the
date of the next Annual General Meeting or after a period of 15
months, whichever is earlier.

The Directors intend to use the authority given by Resolutions
10 and 11 to allot shares and disapply pre-emption rights only
in circumstances where this will be clearly beneficial to

shareholders as a whole. The issue proceeds would be
available for investment in line with the Company’s investment
policy. No issue of shares will be made which would effectively
alter the control of the Company without the prior approval of
shareholders in General Meeting. 

Share Repurchases
At the Annual General Meeting held on 17 July 2009, and at a
subsequent General Meeting, held on 2 March 2010,
shareholders approved the renewal of the authority permitting
the Company to repurchase its own shares.

The Directors wish to renew the authority given by
shareholders at the recent General Meeting. The principal aim
of a share buy-back facility is to enhance shareholder value by
acquiring shares at a discount to net asset value, as and when
the Directors consider this to be appropriate. The purchase of
shares, when they are trading at a discount to net asset value
per share, should result in an increase in the net asset value per
share for the remaining shareholders. This authority, if conferred,
will only be exercised if to do so would result in an increase in
the net asset value per share for the remaining shareholders
and if it is in the best interests of shareholders generally. Any
purchase of shares will be made within guidelines established
from time to time by the Board. It is proposed to seek
shareholder authority to renew this facility for another year at
the Annual General Meeting.

Under the current Listing Rules, the maximum price that may
be paid on the exercise of this authority must not exceed the
higher of (i) 105% of the average of the middle market
quotations for the shares over the five business days
immediately preceding the date of purchase and (ii) the higher
of the last independent trade and the highest current
independent bid on the trading venue where the purchase is
carried out. The minimum price which may be paid is 25p per
share. Shares which are purchased under this authority will
either be cancelled or held as treasury shares.

Special Resolution 12 in the Notice of Annual General Meeting
will renew the authority to purchase in the market a maximum
of 14.99% of shares in issue on 21 June 2010, being the nearest
practicable date prior to the signing of this Report, (amounting
to 6,442,675 shares). Such authority will expire on the date of
the next Annual General Meeting or after a period of 15
months from the date of passing of the resolution, whichever
is earlier. This means in effect that the authority will have to be

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Report of the Directors (continued)
Incorporating the Business Review

The Directors of the Company, whose names appear on
page 63 accept responsibility for the information contained in
this document. To the best of the knowledge and belief of the
Directors (who have taken reasonable care to ensure that such
is the case) the information contained in this document is in
accordance with the facts and does not omit anything likely to
affect the import of such information.

By order of the Board
Frostrow Capital LLP
Company Secretary
21 June 2010

renewed at the next Annual General Meeting or earlier if the
authority has been exhausted. 

Electronic Communications
Ordinary Resolution 13 seeks shareholder approval for the
Company to send them documents, notices and information
either electronically or via the Company’s website.

General Meetings
Special Resolution 14 seeks shareholder approval for the
Company to hold General Meetings (other than Annual
General Meetings) at 14 clear days’ notice.

Significant Changes
Save for the fall in the audited value of the Company’s
net assets from £346.2 million as at 31 March 2010 to
£327.4 million (unaudited) as at 17 June 2010 (being the latest
practicable date prior to the publication of this document),
there has been no significant change in the financial or trading
position of the Company since 31 March 2010.

Change to Investment Policy
Ordinary Resolution 15 seeks shareholder approval for the
Company to make an amendment to its investment policy.

Change of Name
Special Resolution 16 seeks shareholder approval to change the
name of the Company to Worldwide Healthcare Trust PLC.

The authorities being sought under Resolutions 9, 10, 11, 12
and 14 will last until the conclusion of the next Annual General
Meeting or, if less, a period of 15 months.

The Board considers that the resolutions set out above are, in
the Board’s opinion, in the best interests of shareholders as a
whole. Accordingly, the Board unanimously recommends to
shareholders that they vote in favour of the above resolutions
to be proposed at the forthcoming Annual General Meeting.

The Board, which has been so advised by Winterflood
Investment Trusts, believes that the proposed change to the
Company’s benchmark is fair and reasonable as far as the
holders of both the ordinary shares and the subscription shares
of the Company are concerned.

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Statement of Directors’ Responsibilities

25

The Directors are responsible for preparing the annual report
and the financial statements in accordance with applicable
United Kingdom law and regulations.

Company law in the United Kingdom requires the Directors to
prepare financial statements for each financial year. Under this
law the Directors have elected to prepare the financial
statements in accordance with United Kingdom Generally
Accepted Accounting Practice, (United Kingdom standards and
applicable law). Under Company law the Directors must not
approve the financial statements unless they are satisfied that
they give a true and fair view of the state of affairs of the
Company and the profit and loss of the Company for that
period.

In preparing these financial statements, the Directors are
required to:

•

select suitable accounting policies and applied them
consistently;

• make judgements and estimates that are reasonable and

prudent; and

•

state whether applicable UK Accounting Standards have
been followed, subject to any material departures
disclosed and explained in the financial statements.

The Directors are responsible for keeping proper accounting
records that are sufficient to show and explain the Company’s
transactions and which disclose with reasonable accuracy at any
time the financial position of the Company and enable them to
ensure that the financial statements comply with the
Companies Act 2006. They are also responsible for safeguarding
the assets of the Company and hence for taking reasonable
steps for the prevention and detection of fraud and other
irregularities.

Under applicable law and regulation, the Directors are also
responsible for preparing a Report of the Directors, including a
formal statement on Corporate Governance and a Directors’
Remuneration Report that comply with such law and
regulations.

The financial statements are published on the Company’s
website (website address: www.finsburywp.com), which is a
website maintained by the Manager. The maintenance and
integrity of the website is, so far as it relates to the Company, the
responsibility of the Manager. The work carried out by the
Auditors does not involve consideration of the maintenance and
integrity of this website and accordingly, the Auditors accept no
responsibility for any changes that have occurred to the financial
statements since they were initially presented on the website.
Visitors to the website need to be aware that legislation in the
United Kingdom governing the preparation and dissemination of
the financial statements may differ from legislation in their
jurisdiction.

The Directors, whose details can be found on pages 4 and 5,
each confirm that to the best of their knowledge the financial
statements, within the Annual Report, have been prepared in
accordance with applicable accounting standards, give a true
and fair view of the assets, liabilities, financial position and the
profit for the year ended 31 March 2010, and that the Chairman’s
Statement, Review of Investments and the Report of the
Directors include a fair review of the information required by
4.1.8R to 4.2.11R of the FSAs Disclosure and Transparency Rules.

On behalf of the Board
Martin Smith
Chairman 
21 June 2010

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26

Corporate Governance

This Corporate Governance Statement forms part of the Report of the Directors.

CO M P L I A N C E
The Board has considered the principles and
recommendations of the AIC Code of Corporate Governance
(“AIC Code”) by reference to the AIC Corporate Governance
Guide for Investment Companies (“AIC Guide”). The AIC Code,
as explained by the AIC Guide, addresses all the principles set
out in Section 1 of the Combined Code, as well as setting out
additional principles and recommendations on issues that are
of specific relevance to Finsbury Worldwide Pharmaceutical
Trust PLC.

The Board considers that reporting against the principles and
recommendations of the AIC Code, and by reference to the AIC
Guide (which incorporates the Combined Code), will provide
better information to shareholders.

The Company has complied with the recommendations of the
AIC Code and the relevant provisions of Section 1 of the
Combined Code throughout the year ended 31 March 2010
and up to the date of this report, except with regard to the fact
that the Chairman of the Company is Chairman of the
Management Engagement and Remuneration Committee and
as set out below.

The Combined Code includes provision relating to: 

•

•

•

the role of the chief executive (section A.2);

executive directors’ remuneration (section B.1); and

the need for an internal audit function (section C.3).

For the reasons set out in the AIC Guide, and in the preamble
to the AIC Code, the Board considers these provisions are not
relevant to the position of Finsbury Worldwide Pharmaceutical
Trust PLC, being an externally managed investment company.
The Company has therefore not reported further in respect of
these provisions.

I N T E R N A L   AU D I T  
As the Company delegates to third parties its day-to-day
operations and has no employees, the Board has determined
that there are no requirements for an internal audit function.
The Board reviews annually whether a function equivalent to
an internal audit is needed and it will continue to monitor its
systems of internal controls in order to provide assurance that
they operate as intended.

B OA R D   I N D E P E N D E N C E ,   CO M P O S I T I O N   A N D
T E N U R E
The Board, chaired by Martin Smith, currently consists of seven
non-executive Directors. The Directors’ biographical details, set
out on pages 4 and 5, demonstrate a breadth of investment,
commercial and professional experience. Professor Duncan
Geddes has been designated as the Senior Independent
Director. The Directors review their independence annually. The
Directors retire by rotation at every third Annual General
Meeting and any Directors appointed to the Board since the
previous Annual General Meeting also retire and stand for
election. Any Director who has served on the Board for more
than nine years is subject to annual re-election. Jo Dixon retires
by rotation in accordance with the Company’s Articles of
Association and, being eligible, offers herself for re-election at
the forthcoming Annual General Meeting. Paul Gaunt is a
Director of The Biotech Growth Trust PLC for which OrbiMed also
acts as Investment Manager; he has also served on the Board for
over nine years. Despite being considered by the Board to be
independent in character and judgement Mr Gaunt is not
considered to be an Independent Director. Samuel D Isaly is
Managing Partner of OrbiMed, the Company’s Investment
Manager, and has also served on the Board for over nine years.
Mr Isaly is therefore not considered to be an Independent
Director. Professor Geddes and Anthony Townsend have both
also served on the Board for over nine years. However, the Board
considers them to be independent in character and judgement
and, in accordance with the AIC Code, does not believe that the
criterion of length of service should necessarily preclude them
from being considered independent; they also have no other
links to the Investment Manager and have a wide range of other
interests. The Board has considered the position of Ms Dixon and
Messrs Gaunt, Isaly, Townsend and Professor Geddes, as part of
the evaluation process, and believes that it would be in the
Company’s best interests to propose them for re-election at the
forthcoming Annual General Meeting. In line with the
Company’s strong commitment to its corporate governance
responsibilities, the Board regularly reviews its performance and
composition to ensure it has the correct mix of relevant skills
and experience for the good conduct of the Company’s
business. As part of this process the Board is in the process of
agreeing a programme of refreshment, which will see its
membership change as current Directors retire in an orderly
manner, and new Directors are appointed.

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Corporate Governance (continued)

27

None of the Directors has a service contract with the
Company. New Directors are appointed with the expectation
that they will serve for a minimum period of three years. Any
Director may resign in writing to the Board at any time. The
terms of their appointment are detailed in a letter sent to them
when they join the Board. These letters are available for
inspection at the offices of the Company’s Manager and will be
available at the Annual General Meeting. When a new Director is
appointed to the Board, they are provided with all relevant
information regarding the Company and their duties and
responsibilities as a Director. In addition, a new Director will also
spend time with representatives of the Manager and Investment
Manager in order to learn more about their processes and
procedures. The Board also receives regular briefings from,
amongst others, the Auditors and the Company Secretary
regarding any proposed developments or changes in laws or
regulations that could affect the Company and/or the Directors.

T H E   B OA R D ’S   R E S P O N S I B I L I T I E S
The Board is responsible for efficient and effective leadership of
the Company and regularly reviews the schedule of matters
reserved for its decision. The Board meets at least on a
quarterly basis and at other times as necessary. The Board is
responsible for all aspects of the Company’s affairs, including
the setting of parameters for and the monitoring of investment
strategy, the review of investment performance (including
peer group performance) and investment policy. It also has
responsibility for all corporate strategy issues, dividend policy,
share buy-back policy, gearing, share price and
discount/premium monitoring and corporate governance
matters. To enable them to discharge their responsibilities,
prior to each meeting the Directors are provided, in a timely
manner, with a comprehensive set of papers giving detailed
information on the Company’s transactions, financial position
and performance. Representatives of the Manager and
Investment Manager attend each Board meeting, enabling the
Directors to seek clarification on specific issues or to probe
further on matters of concern; a full written report is also
received from the Manager and Investment Manager at each
quarterly meeting. In light of these reports, the Board gives
direction to the Investment Manager with regard to the
Company’s investment objectives and guidelines. Within these
established guidelines, the Investment Manager takes

decisions as to the purchase and sale of individual investments.

There is an agreed procedure for Directors, in the furtherance
of their duties, to take independent professional advice, if
necessary, at the Company’s expense. The Directors have
access to the advice and services of the Company Secretary,
through its appointed representative, who is responsible to the
Board for ensuring that Board procedures are followed.

P E R F O R MA N C E   E VA LUAT I O N
The Board has carried out an evaluation process for the year
ended 31 March 2010, independently managed by Professor
Geddes, the Senior Independent Director. This took the form of
a questionnaire followed by discussions to identify how the
effectiveness of its activities, including the performance of
investment, Directors and the Company’s  committees,
together with the Company’s policies and processes, might be
improved. The results of the evaluation process were presented
to and discussed by the Board and, as a result, it was agreed
that the current Directors contributed effectively and that all
had the skills and experience which are relevant to the
leadership and direction of the Company.

CO N F L I C T   O F   I N T E R E S T
On 1 October 2008 it became a statutory requirement that a
Director must avoid a situation in which he or she has, or can
have, a direct or indirect interest that conflicts, or possibly may
conflict, with the Company’s interests (a “situational conflict”).
The Company’s Articles of Association were amended at the
last Annual General Meeting to give the Directors authority to
approve such situations, where appropriate.

It is the responsibility of each individual Director to avoid an
unauthorised conflict situation arising. He or she must request
authorisation from the Board as soon as he or she becomes
aware of the possibility of a situational conflict arising.

The Board is responsible for considering Directors’ requests for
authorisation of situational conflicts and for deciding whether
they should be authorised. The factors to be considered will
include whether the situational conflict could prevent the
Director from performing his or her duties, whether it has, or
could have, any impact on the Company and whether it could
be regarded as likely to affect the judgment and/or actions of
the Director in question. When the Board is deciding whether

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Corporate Governance (continued)

to authorise a conflict or potential conflict, only Directors who
have no interest in the matter being considered are able to take
the relevant decision, and in taking the decision the Directors
must act in a way they consider, in good faith, will be most
likely to promote the Company’s success. The Directors are able
to impose limits or conditions when giving authorisation if they
think this is appropriate in the circumstances.

the membership of the Committees as at 31 March 2010 are
shown with the Directors’ biographies on pages 4 and 5.
Following a review by the Board during the year, it was agreed
that the Company’s Remuneration Committee should be
reconstituted as Management Engagement and Remuneration
Committee under the chairmanship of Mr Martin Smith, the
Chairman of the Company.

A register of conflicts is maintained by the Company Secretary
and is reviewed at quarterly Board meetings, to ensure that
any authorised conflicts remain appropriate. Directors are
required to confirm at these meetings whether there has been
any change to their position.

The Directors must also comply with the statutory rules
requiring company directors to declare any interest in an actual
or proposed transaction or arrangement with the Company.

CO M M I T T E E S   O F  T H E   B OA R D
During the year the Board delegated certain responsibilities and
functions to committees. Copies of the full terms of reference,
which clearly define the responsibilities of each Committee, can be
obtained from the Company Secretary, will be available for
inspection at the Annual General Meeting, and can be found at
the Company’s website at www.finsburywp.com. Following a
review by the Board in 2008, it was agreed that due to the size of
the Board, the membership of the Management Engagement and
Remuneration and Nominations Committees should comprise the
whole Board, under the chairmanship of the Chairman of the
Company and Professor Geddes respectively (provided that a
majority of the Directors present are independent). It was further
agreed that the membership of the Audit Committee comprise
the following independent Directors: Jo Dixon (Chairman), Dr
David Holbrook, Professor Duncan Geddes and Anthony
Townsend. Directors who are not members of the Audit
Committee may attend at the invitation of the Chairman. Details of

The table overleaf details the number of Board and Committee
meetings attended by each Director. During the year there
were four Board meetings, three Board Committee meetings,
two Audit Committee meetings, one meeting of the
Nominations Committee, one meeting of the Management
Engagement and Remuneration Committee and three Share
Allotment Committee meetings.

N O M I N AT I O N S   CO M M I T T E E
The Nominations Committee is responsible for the Board
appraisal process and for making recommendations to the
Board on the appointment of new Directors. Where
appropriate, each Director is invited to submit nominations and
external advisers may be used to identify potential candidates.

MA N AG E M E N T   E N G AG E M E N T   A N D
R E M U N E R AT I O N CO M M I T T E E
The level of Directors’ fees is reviewed on a regular basis
relative to other comparable investment companies and in the
light of Directors’ responsibilities. Neither the Chairman nor
individual Directors participate in discussions involving
personal remuneration. Details of the fees paid to the Directors
in the year under review are detailed in the Directors’
Remuneration Report on pages 32 and 33.

This committee also reviews the terms of engagement of the
Investment Manager, the Manager and the Company’s other
service providers.

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Corporate Governance (continued)

29

M E E T I N G   AT T E N DA N C E
The number of meetings held during the year of the Board and its Committees, and each Director’s attendance level, is shown below:

Type and number of meetings
held in 2009/10
Martin Smith
Josephine Dixon
Paul Gaunt
Professor Duncan Geddes
Dr David Holbrook
Samuel D Isaly
Anthony Townsend

Board
(4)
4
4
4
4
4
4
4

Board
Committee
(3)
2
2
N/A
N/A
1
N/A
3

Allotment
Committee
(3)
3
1
1
N/A
N/A
1
N/A

Audit
Committee
(2)
N/A
2
N/A
2
2
N/A
2

Management
Engagement and
Remuneration
Committee
(1)
1
1
1
1
1
1
1

Nominations
Committee
(1)
1
1
1
1
1
1
1

All of the Directors attended the Annual General Meeting held on 17 July 2009.
Mr Townsend attended the General Meeting of the Company held on 4 September 2009.
Professor Geddes attended the General Meeting of the Company held on 2 March 2010.

AUDIT COMMITTEE
The Audit Committee meets at least twice a year and is
responsible for the review of the interim and annual financial
statements, the nature and scope of the external audit and the
findings therefrom and the terms of appointment of the
Auditors, including their remuneration and the provision of any
non-audit services by them.

The Audit Committee meets representatives of the Manager and
Investment Manager and their Compliance Officers who report
as to the proper conduct of business in accordance with the
regulatory environment in which the Company, Manager and
Investment Manager operate. The Company’s external Auditors
also attend meetings of this Committee at its request and report
on their work procedures and their findings in relation to the
Company’s statutory audit. They also have the opportunity to
meet with the Committee without representatives of the
Manager or the Investment Manager being present. The Audit
Committee reviews the need for non-audit services and
authorises such on a case by case basis, having consideration to
the cost effectiveness of the services and the independence and
objectivity of the Auditors. Non-audit fees of £15,000 were paid
to Ernst & Young LLP during the year for their review of the
Company’s options strategy and for the provision of tax advice in
relation to royalty bonds and convertible preferred equity
certificates (CPECs). The Board has concluded, on the
recommendation of the Audit Committee, that the Auditors
continued to be independent and that their reappointment be
proposed at the Annual General Meeting.

INTERNAL CONTROLS
The Directors are responsible for the Company’s system of internal
control which is designed to safeguard the Company’s assets,
maintain proper accounting records and ensure that financial
information used within the business, or published, is reliable.
However, such a system can only be designed to manage rather
than eliminate the risk of failure to achieve business objectives
and therefore can only provide reasonable, but not absolute,
assurance against fraud, material misstatement or loss.
Risk assessment and the review of internal controls are
undertaken by the Board in the context of the Company’s overall
investment objective. The review covers the key business,
operational, compliance and financial risks facing the Company.
In arriving at its judgement of what risks the Company faces, the
Board has considered the Company’s operations in the light of
the following factors: 

•

•

•

the nature and extent of risks which it regards as
acceptable for the Company to bear within its overall
business objective;

the threat of such risks becoming a reality; and

the Company’s ability to reduce the incidence and impact
of risk on its performance.

Against this background, the Board has split the review of risk
and associated controls into five sections reflecting the nature
of the risks being addressed. These sections are as follows:

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Corporate Governance (continued)

•

•

•

•

•

corporate strategy;

investment activity;

published information, compliance with laws and
regulations;

service providers; and

financial activity.

The Company has appointed agents to provide administrative
services to the Company. The Company has obtained from its
various service providers assurances and information relating to
their internal systems and controls to enable the Board to make
an appropriate risk and control assessment, including the
following:

•

•

•

•

details of the control environment in operation;

identification and evaluation of risks and control objectives; 

review of communication methods and procedures; and

assessment of the control procedures.

The key procedures which have been established to provide
internal financial controls are as follows:

•

•

•

•

investment management is provided by OrbiMed Capital
LLC. The Board is responsible for setting the overall
investment policy and monitors the actions of the
Investment Manager at regular Board meeting;

administration, company secretarial and marketing duties for
the Company are performed by Frostrow Capital LLP;

custody of assets is undertaken by Goldman Sachs & Co.
New York;

the Board clearly defines the duties and responsibilities of
their agents and advisers. The appointment of agents and
advisers to the Company is conducted by the Board after
consideration of the quality of the parties involved; the Board
monitors their ongoing performance and contractual
arrangements; 

All of the Company’s management functions are performed by
third parties whose internal controls are reviewed by the Board or
on its behalf by Frostrow Capital LLP.

In accordance with guidance issued to directors of listed
companies, (“the Turnbull Guidance”) the Directors confirm that
they have carried out a review of the effectiveness of the system
of internal financial control during the year and up to the date of
approval of the financial statements, as set out above.

RELATIONS WITH SHAREHOLDERS
The Board reviews the shareholder register at each Board
meeting. The Company has regular contact with its institutional
shareholders particularly through the Manager. The Board
supports the principle that the Annual General Meeting be used
to communicate with private investors. The full Board attends the
Annual General Meeting under the Chairmanship of the
Chairman of the Board. Details of proxy votes received in respect
of each resolution are made available to shareholders at the
meeting and are also published on the Company’s website at
www.finsburywp.com. Representatives from the Investment
Manager attend the Annual General Meeting and give a
presentation on investment matters to those present. The
Company has adopted a nominee share code which is set out
on page 31.

The Board receives marketing and public relations reports from
the Manager to whom the marketing function has been
delegated. The Board reviews and considers the marketing plans
of the Manager on a regular basis.

The annual and interim financial reports, the interim
management statements and a monthly fact sheet are available
to all shareholders. The Board considers the format of the annual
and interim financial reports so as to ensure they are useful to all
shareholders and others taking an interest in the Company. In
accordance with best practice, the annual report, including the
Notice of the Annual General Meeting, is sent to shareholders at
least 20 working days before the Meeting. Separate resolutions
are proposed for substantive issues.

• mandates for authorisation of investment transactions and

expense payments are set by the Board; and

•

the Board reviews financial information produced by the
Investment Manager and the Manager in detail on a regular
basis.

EXERCISE OF VOTING POWERS
The Board has delegated authority to the Investment Manager to
vote the shares owned by the Company that are held on its
behalf by its custodian, Goldman Sachs & Co. New York. The
Board has instructed that the Investment Manager submit votes

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Corporate Governance (continued)

31

for such shares wherever possible. This accords with current best
practice whilst maintaining a primary focus on financial returns.
The Investment Manager may refer to the Board on any matters
of a contentious nature. The Company does not retain voting
rights on any shares that are subject to rehypothecation in
connection with the loan facility provided by Goldman Sachs &
Co. New York.

ACCOUNTABILITY AND AUDIT
The Statement of Directors’ Responsibilities in respect of the
financial statements is set out on page 25. The report of the
Auditors is set out on pages 34 and 35. The Board has delegated
contractually to external agencies, including the Manager and
the Investment Manager, the management of the portfolio,
custodial services (which includes the safeguarding of the
Company’s assets), the day to day marketing, accounting
administration, company secretarial requirements and
registration services. Each of these contracts was entered into
after full and proper consideration by the Board of the quality
and cost of the services offered, including the control systems in
operation in so far as they relate to the affairs of the Company.
The Board receives and considers regular reports from the

Manager and the Investment Manager and ad hoc reports and
information are supplied to the Board as required.

NOMINEE SHARE CODE
Where shares are held in a nominee company name, the
Company undertakes:

•

•

•

to provide the nominee company with multiple copies of
shareholder communications, so long as an indication of
quantities has been provided in advance;

to allow investors holding shares through a nominee
company to attend General Meetings, provided the correct
authority from the nominee company is available; and

that investors in the Alliance Trust Savings Scheme or ISA are
automatically sent shareholder communications, including
details of General Meetings, together with a form of direction
to facilitate voting and to seek authority to attend.

Nominee companies are encouraged to provide the necessary
authority to underlying shareholders to attend the Company’s
General Meetings. 

Shareholder Analysis

as at 31 March

2010

2010
number of % of issued
number of % of issued subscription subscription
shares^

shares share capital

shares^

2010

2010

2009

2009
number of % of issued
shares share capital

2009

2009
number of % of issued
warrants#
warrants#

Nominee Companies*
Other Institutions, Investment 
Funds and Companies
Private Individuals
Banks and Bank Nominees

34,236,796

77.4

7,978,398

91.6

34,386,134

83.1

8,330,379

6,867,690
1,390,944
1,739,860

15.5
3.2
3.9

118,963
342,682
271,470

1.4
3.9
3.1

3,957,834
1,316,008
1,701,455

9.6
3.2
4.1

722,709
544,730
1,147,792

77.5

6.7
5.1
10.7

Total shares/warrants in issue

44,235,290*

100.0

8,711,513

100.00

41,361,431*

100.0

10,745,610†

100.0

*

Includes Alliance Trust 

Savings Scheme, and ISA 
clients

2,003,705

4.5

372,160

4.1

2,013,822

4.9

126,341

1.2

#
†
^

Warrants to subscribe for shares, created on 17 December 2004.
All of the remaining 10,745,610 warrants in issue on 31 July 2009, the last exercise date, were exercised on this date.
Subscription shares, created on 4 September 2009.

217687 Finsbury WWP pp32-pp39  6/21/10  3:08 PM  Page 32

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Directors’ Remuneration Report

The fees for the Directors are determined within the limits set
out in the Company’s Articles of Association, the maximum
aggregate amount currently being £200,000. Directors are not
eligible for bonuses, pension benefits, share options, long-term
incentive schemes or other benefits. The policy is for the
Chairman of the Board and Chairman of the Audit Committee
to be paid higher fees than the other Directors to reflect their
more onerous roles and additional responsibilities.

D I R E C TO R S’ S E R V I C E   CO N T R AC TS
It is the Board’s policy that none of the Directors has a service
contract. The terms of their appointment provide that
Directors shall retire and be subject to election at the first
Annual General Meeting after their appointment and
re-election at least every three years thereafter. The terms also
provide that a Director may resign by notice in writing to the
Board at any time and may be removed without notice and
that compensation will not be due on leaving office. The
Company’s policy is for the Directors to be remunerated in the
form of fees payable quarterly in arrears, to the Director
personally or to a specified third party.

YO U R   CO M PA NY ’S   P E R F O R MA N C E
The Regulations require a line graph be included in the
Directors’ Remuneration Report comparing, for a period of five
years, on a cumulative basis, the total share price return
(assuming all dividends are reinvested) to shareholders and the
total shareholder return on a notional investment made up of
shares of the same kind and number as those by reference to
which the Datastream World Pharmaceutical and
Biotechnology Index (total return, sterling adjusted), chosen as
it is the Company’s stated benchmark, is calculated. 

The Board has prepared this report in accordance with the
requirements of Section 420 to 422 of the Companies
Act 2006. An ordinary resolution for the approval of this report
will be put to the members at the forthcoming Annual General
Meeting.

The law requires the Company’s auditors to audit certain of the
disclosures provided. Where disclosures have been audited,
they are indicated as such. The Auditors’ opinion is included in
their report on pages 34 and 35.

MA N AG E M E N T E N G AG E M E N T A N D
R E M U N E R AT I O N   CO M M I T T E E
The Company has seven non-executive Directors, five of whom
are considered by the Board to be independent. The whole
Board fulfils the function of the Management Engagement and
Remuneration Committee (provided that a majority of the
Directors present are independent). The Board may utilise the
services of the Company Secretary or external advisers to
provide advice when the Directors consider the level of
Directors’ fees. 

The Directors’ fees are reviewed annually by the Management
Engagement and Remuneration Committee and such review
will not necessarily result in a change to the rates paid; the
current level of fees paid to the Directors has been in place
since 2004. During the year, the Management Engagement
and Remuneration Committee carried out a review of the level
of Directors’ fees in relation both to fees paid to the boards of
other investment trust companies and also to the Board’s
corporate governance obligations. The Board decided, on the
advice of the Management Engagement and Remuneration
Committee, that the fees paid to the Directors should be
increased with effect from 1 April 2010. The revised fee levels
are set out on page 33.

P O L I C Y   O N   D I R E C TO R S’ F E E S
The Board’s policy is that the remuneration of Directors should
reflect the experience of the Board as a whole, be fair and
comparable to that of other investment trusts that are similar
in size, have a similar capital structure (Ordinary shares), and
have a similar investment objective. It is intended that this
policy will continue for the year ending 31 March 2011 and
subsequent years. 

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Directors’ Remuneration Report (continued)

33

D I R E C TO R S’ E M O LU M E N TS   F O R  T H E  YE A R   (AU D I T E D)
The Directors who served in the year received the following emoluments in the form of fees:

Martin Smith+
Josephine Dixon (Chairman of the Audit Committee)
Paul Gaunt
Professor Duncan Geddes
Dr David Holbrook
Ian Ivory*
Samuel D Isaly
Anthony Townsend

*
Retired from the Board on 23 July 2008.
+
Appointed Chairman 23 July 2008.

Fees
2010
£’000

30
21
19
19
19
–
19
19

146

Fees
2009
£’000

27
21
19
19
19
9
19
19

152

With effect from 1 April 2010 the fees paid to the Directors increased as follows:

Chairman £35,000 pa
Chairman of the Audit Committee £25,000 pa
Director £22,000 pa

S H A R E H O L D E R  TOTA L   R E T U R N   F O R  T H E   F I V E  YE A R S  TO   3 1   MA R C H   2 0 1 0

180

170

160

150

140

130

120

110

100

90

80

70

60

50

Mar
05

Mar
06
Benchmark index 

Rebased to 100 as at 31 March 2005
Source: Morningstar & Thomson Reuters

Mar
07

Mar
08

Mar
09
Finsbury Worldwide Share price (total return)

Mar
10

A P P R O VA L
The Directors’ Remuneration Report on pages 32 and 33 was approved by the Board of Directors on 21 June 2010 and signed on
its behalf by:

Martin Smith (Chairman)

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34

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Independent Auditors’ Report 
to the Members of Finsbury Worldwide Pharmaceutical Trust PLC

We have audited the financial statements of Finsbury
Worldwide Pharmaceutical Trust PLC for the year ended
31 March 2010 which comprise the Income Statement,
Reconciliation of Movements in Shareholders’ Funds, Balance
Sheet, Cash Flow Statement and the related notes 1 to 19. The
financial reporting framework that has been applied in their
preparation is applicable law and United Kingdom Accounting
Standards (United Kingdom Generally Accepted Accounting
Practice).

This report is made solely to the Company’s members, as a
body, in accordance with Chapter 3 of Part 16 of the
Companies Act 2006. Our audit work has been undertaken so
that we might state to the Company’s members those matters
we are required to state to them in an auditor’s report and for
no other purpose. To the fullest extent permitted by law, we do
not accept or assume responsibility to anyone other than the
Company and the Company’s members as a body, for our
audit work, for this report, or for the opinions we have formed.

R E S P E C T I V E   R E S P O N S I B I L I T I E S   O F
D I R E C TO R S   A N D   AU D I TO R S
As explained more fully in the Statement of Directors’
Responsibilities set out on page 25, the Directors are
responsible for the preparation of the financial statements and
for being satisfied that they give a true and fair view. Our
responsibility is to audit the financial statements in accordance
with applicable law and International Standards on Auditing
(UK and Ireland). Those standards require us to comply with
the Auditing Practices Board’s (APB’s) Ethical Standards for
Auditors.

S CO P E   O F  T H E   AU D I T   O F  T H E   F I N A N C I A L
S TAT E M E N TS
An audit involves obtaining evidence about the amounts and
disclosures in the financial statements sufficient to give
reasonable assurance that the financial statements are free
from material misstatement, whether caused by fraud or error.
This includes an assessment of: whether the accounting
policies are appropriate to the Company’s circumstances and
have been consistently applied and adequately disclosed; the
reasonableness of significant accounting estimates made by
the Directors; and the overall presentation of the financial
statements. 

O P I N I O N   O N   F I N A N C I A L   S TAT E M E N TS
In our opinion the financial statements:

•

•

•

give a true and fair view of the state of the Company’s
affairs as at 31 March 2010 and of its profit for the year
then ended;

have been properly prepared in accordance with United
Kingdom Generally Accepted Accounting Practice; and

have been prepared in accordance with the requirements
of the Companies Act 2006.

O P I N I O N   O N   OT H E R   MAT T E R S   P R E S C R I B E D
BY  T H E   CO M PA N I E S   AC T   2 0 0 6
In our opinion:

•

•

the part of the Directors’ Remuneration Report to be
audited has been properly prepared in accordance with
the Companies Act 2006; 

the information given in the Directors’ Report for the
financial year for which the financial statements are
prepared is consistent with the financial statements.

MAT T E R S   O N  W H I C H  W E   A R E   R E Q U I R E D  TO
R E P O R T   BY   E XC E P T I O N
We have nothing to report in respect of the following:

Under the Companies Act 2006 we are required to report to
you if, in our opinion:

•

•

•

adequate accounting records have not been kept, or
returns adequate for our audit have not been received
from branches not visited by us; or

the financial statements and the part of the Directors’
Remuneration Report to be audited are not in agreement
with the accounting records and returns; or

certain disclosures of directors’ remuneration specified by
law are not made; or

• we have not received all the information and explanations

we require for our audit; 

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Independent Auditors’ Report (continued)

35

Under the Listing Rules we are required to review:

•

•

the Directors’ statement, set out on page 18, in relation to
going concern; and

the part of the Corporate Governance Statement on pages
26 to 31 of the financial statements relating to the
Company’s compliance with the nine provisions of the
June 2008 Combined Code specified for our review.

Caroline Gulliver, (Senior Statutory Auditor)
for and on behalf of Ernst & Young LLP, Statutory Auditor
London
21 June 2010

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36

Income Statement

for the year ended 31 March 2010

Gains on investments held at fair 
value through profit or loss

Exchange gains/(losses) on currency balances
Income from investments held at fair value

through profit or loss

Investment management, management and 

and performance fees

Other expenses

Net return before 

finance charges and taxation

Finance costs

Net return before taxation
Taxation on net return on ordinary 

activities

Net return after taxation

Return per share – basic

Return per share – diluted

9

2

3
4

5

6

7

7

2010
Revenue
£’000

Notes

2010
Capital
£’000

76,180
3,946

2010
Total
£’000

76,180
3,946

2009
Revenue
£’000

2009
Capital
£’000

2009
Total
£’000

–
–

76,505
(12,042)

76,505
(12,042)

–
–

5,825

–

5,825

4,018

–

4,018

(133)
(506)

5,186
(11)

5,175

(965)

4,210

9.5p

9.5p

(5,025)
–

75,101
(212)

74,889

303

75,192

170.5p

170.5p

(5,158)
(506)

80,287
(223)

80,064

(662)

79,402

180.0p

180.0p

(116)
(588)

3,314
(29)

3,285

(866)

2,419

5.5p

5.4p

(2,436)
–

62,027
(543)

61,484

360

61,844

141.4p

138.2p

(2,552)
(588)

65,341
(572)

64,769

(506)

64,263

146.9p

143.6p

The “Total” column of this statement is the Income Statement of the Company. The “Revenue” and “Capital” columns are
supplementary to this and are prepared under guidance published by the Association of Investment Companies.

All revenue and capital items in the above statement derive from continuing operations.

The Company has no recognised gains and losses other than those disclosed in the Income Statement and Reconciliation of
Movements in Shareholders’ Funds. Accordingly no separate Statement of Total Recognised Gains and Losses has been presented.

No operations were acquired or discontinued in the year.

The accompanying notes are an integral part of this statement.

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Reconciliation of Movements 
in Shareholders’ Funds

37

For the year ended 31 March 2010

Ordinary Subscription
share
capital
£’000

share
capital
£’000

At 31 March 2009
Net return from ordinary activities  

11,105

after taxation

Dividend paid in respect of year 

ended 31 March 2009

Proceeds from warrant exercise 
Transfer from warrant reserve 

following exercise of warrants
Subscription shares issued less 

issue costs

Subscription shares exercised for 

ordinary shares

Shares purchased including 

expenses

At 31 March 2010

–

–
2,686

–

–

184

(1,331)

12,644

–

–

–
–

–

97

(7)

–

90

For the year ended 31 March 2009

Share
premium
account
£’000

117,706

–

–
47,174

Warrant
reserve
£’000

Capital
reserve
£’000

Capital
redemption
reserve
£’000

Revenue
reserve
£’000

Total
£’000

7,417

118,709

3,678

4,402

263,017

–

–
–

75,192

–
–

–

(295)

7

–

–
–

–

–

–

(48,453)

145,160

1,331

5,009

4,210

79,402

(1,982)
–

(1,982)
49,860

–

–

–

–

–

(198)

4,535

(48,453)

6,630

346,181

7,417

(7,417)

–

4,351

–

176,648

–

–

–

–

Ordinary Subscription
share
capital
£’000

share
capital
£’000

At 31 March 2008
Net return from ordinary activities  

11,772

after taxation

Dividend paid in respect of year 

ended 31 March 2008

Proceeds from warrant exercise
Transfer from warrant reserve 

following exercise of warrants

Shares purchased including 

expenses

At 31 March 2009

–

–
3

–

(670)

11,105

–

–

–
–

–

–

–

Share
premium
account
£’000

117,639

Warrant
reserve
£’000

7,426

–

–
58

9

–

–

–
–

(9)

–

Capital
reserve
£’000

81,611

61,844

–
–

–

(24,746)

117,706

7,417

118,709

Capital
redemption
reserve
£’000

Revenue
reserve
£’000

Total
£’000

3,008

3,327

224,783

–

–
–

–

670

3,678

2,419

64,263

(1,344)
–

(1,344)
61

–

–

–

(24,746)

4,402

263,017

The accompanying notes are an integral part of this statement.

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38

Balance Sheet

as at 31 March 2010

Fixed assets
Investments held at fair value through profit or loss
Derivative – OTC swaps

Current assets
Debtors
Derivative – financial instruments
Cash at bank

Current liabilities
Creditors: amounts falling due within one year
Derivative – financial instruments

Net current liabilities

Total net assets

Capital and reserves
Ordinary share capital
Subscription share capital
Share premium account
Warrant reserve
Capital reserve
Capital redemption reserve
Revenue reserve

Total shareholders’ funds

Net asset value per share – basic

Diluted net asset value per share – for subscription shares/warrants

Notes

9
9 & 12

10
9 & 12
16

11
9 & 12

13
13

19

14

14

2010
£’000

383,599
–

383,599

1,757
628
–

2,385

(39,803)
–

(39,803)

(37,418)

346,181

12,644
90
176,648
–
145,160
5,009
6,630

346,181

780.8p

752.7p

2009
£’000

294,928
10,321

305,249

1,307
–
9,979

11,286

(52,564)
(954)

(53,518)

(42,232)

263,017

11,105
–
117,706
7,417
118,709
3,678
4,402

263,017

635.9p

600.5p

The financial statements on pages 36 to 55 were approved by the Board of Directors and authorised for issue on 21 June 2010
and were signed on its behalf by:

Martin Smith
Chairman

The accompanying notes are an integral part of this statement.

Finsbury Worldwide Pharmaceutical Trust PLC – Company Registration Number 3023689 (Registered in England)

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Cash Flow Statement

for the year ended 31 March 2010

39

Net cash inflow/(outflow) from operating activities

Notes

15

2010
£’000

2,108

2009
£’000

(61)

Servicing of finance
Interest paid

Taxation
Taxation recovered

Financial investments
Purchases of investments and derivatives
Sales of investments and derivatives

Net cash (outflow)/inflow from financial investment

Equity dividends paid

Net cash (outflow)/inflow before financing

Financing
Issue of ordinary shares
Proceeds from exercise of warrants
Subscription share issue costs
Purchase of own shares
Subscription shares exercised for ordinary shares
Repayment of short term loans

Net cash inflow/(outflow) from financing

(223)

(582)

93

91

(265,795)
250,859

(14,936)

(1,982)

(14,940)

–
49,860
(198)
(49,061)
4,535
–

5,136

(251,520)
257,286

5,766

(1,344)

3,870

61
–
–
(25,068)
–
(14,813)

(39,820)

Decrease in cash

16

(9,804)

(35,950)

The accompanying notes are an integral part of this statement.

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40

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Notes to the Financial Statements

1 . ACCO U N T I N G   P O L I C I E S
The principal accounting policies, all of which have been applied consistently throughout the year in the preparation of these
financial statements, are set out below:

(a) Basis of Preparation
The financial statements have been prepared in accordance with United Kingdom generally accepted accounting standards (UK
GAAP) and with the Statement of Recommended Practice ‘Financial Statements of Investment Trust Companies and Venture
Capital Trusts’ dated January 2009 (the ‘SORP’).

The Company’s financial statements are presented in sterling. All values are rounded to the nearest thousand pounds (£’000)
except where otherwise indicated.

(b) Investments held at fair value through profit or loss
Listed investments have been designated by the Board as held at fair value through profit or loss and accordingly are valued at
fair value, deemed to be bid market prices. 

Unquoted investments have also been designated by the Board as held at fair value through profit or loss, and are valued by the
Directors using primary valuation techniques such as earnings multiples, option pricing models, discounted cash flow analysis
and recent transactions.

Changes in the fair value of investments held at fair value through profit or loss and gains and losses on disposal are recognised
in the Income Statement as ‘gains or losses on investments held at fair value through profit or loss’. Also included within this
caption are transaction costs in relation to the purchase or sale of investments, including the difference between the purchase
price of an investment and its bid price at the date of purchase. All purchases and sales are accounted for on a trade date basis.

The Company has classified its financial assets designated at fair value through profit or loss and the fair value of derivative
financial instruments using a fair value hierarchy that reflects the significance of the inputs used in making the fair value
measurements. The hierarchy has the following levels:

•

•

•

Level 1 – quoted prices (unadjusted) in active markets for identical assets or liabilities;

Level 2 – inputs other than quoted prices included with Level 1 that are observable for the asset or liability, either directly
(i.e. as prices) or indirectly (i.e. derived from prices); and

Level 3 – inputs for the asset or liability that are not based on observable market data (unobservable inputs).

Investment Income

(c)
Dividends receivable on equity shares are recognised on the ex-dividend date. Where no ex-dividend date is quoted, dividends
are recognised when the Company’s right to receive payment is established.

Income from fixed interest securities is recognised on a time apportionment basis so as to reflect the effective interest rate.

Deposit interest is accounted for on an accruals basis.

(d) Expenses
All expenses are accounted for on an accruals basis. Expenses are charged through the revenue column of the Income Statement
except as follows:

(i) expenses which are incidental to the acquisition or disposal of an investment, categorised as fixed assets held at fair value

through profit or loss are charged to the capital column of the Income Statement; and

(ii) expenses are charged to the capital column of the Income Statement where a connection with the maintenance or

enhancement of the value of the investments can be demonstrated. In this respect the investment management and
management fees have been charged to the Income Statement in line with the Board’s expected long-term split of returns, in
the form of capital gains and income, from the Company’s portfolio. As a result 5% of the investment management and
management fees are charged to the revenue column of the Income Statement and 95% are charged to the capital column
of the Income Statement.

Any performance fee accrued or paid is charged in full to the capital column of the Income Statement.

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Notes to the Financial Statements (continued)

41

1 . ACCO U N T I N G   P O L I C I E S   (CO N T I N U E D)

(e) Finance costs
Finance costs are accounted for on an accruals basis. Finance costs are charged to the Income Statement in line with the Board’s
expected long-term split of returns, in the form of capital gains and income, from the Company’s portfolio. As a result 5% of the
finance costs are charged to the revenue column of the Income Statement and 95% are charged to the capital column of the
Income Statement. Finance charges, if applicable, including interest payable and premiums on settlement or redemption, are
accounted for on an accruals basis in the Income Statement using the effective interest rate method and are added to the
carrying amount of the instrument to the extent that they are not settled in the period in which they arise.

(f) Taxation
The tax effect of different items of expenditure is allocated between capital and revenue using the marginal basis.

Deferred taxation is provided on all timing differences that have originated but not been reversed by the Balance Sheet date
other than those differences regarded as permanent. This is subject to deferred tax assets only being recognised if it is considered
more likely than not that there will be suitable profits from which the reversal of timing differences can be deducted. Any liability
to deferred tax is provided for at the average rate of tax expected to apply. Deferred tax assets and liabilities are not discounted to
reflect the time value of money.

(g) Foreign Currency
The results and financial position of the Company are expressed in sterling, which is the functional and presentational currency of
the Company. Sterling is the functional currency because it is the currency of the primary economic environment in which the
Company operates.

Transactions recorded in overseas currencies during the year are translated into sterling at the appropriate daily exchange rates.
Assets and liabilities denominated in overseas currencies at the Balance Sheet date are translated into sterling at the exchange
rates ruling at the date.

Any gains or losses on the translation of foreign currency balances, whether realised or unrealised, are taken to the capital or the
revenue column of the Income Statement, depending on whether the gain or loss is of a capital or revenue nature.

(h) Derivative Financial Instruments
The Company uses derivative financial instruments (namely put and call options). The merits and rationale behind such strategies
are to enhance the capital return of the portfolio, facilitate management of the portfolio volatility and improve the risk-return
profile of the Company relative to its benchmark.

All derivative instruments are valued at fair value in the Balance Sheet in accordance with FRS 26: ‘Financial instruments:
measurement’.

Each investment in options is reviewed on a case-by-case basis and are all deemed to be capital in nature. As such, all gains and
losses on the above strategies have been debited or credited to the capital column of the Income Statement.

All gains and losses on over-the-counter (OTC) equity swaps, during the swap term, are accounted for as investment holding
gains or losses on investments. Where there has been a re-positioning of the swap, gains and losses are accounted for on a
realised basis. All such gains and losses have been debited or credited to the capital column of the Income Statement.

(i) Capital Reserves
The following are transferred to this reserve:

– gains and losses on the realisation of investments;

–

–

–

–

realised and unrealised exchange differences of a capital nature; 

expenses, together with the related taxation effect, in accordance with the above policies; 

increases and decreases in the valuation of investments held at the year end; and

unrealised exchange differences of a capital nature.

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Notes to the Financial Statements (continued)

2 .

I N CO M E   F R O M   I N V E S T M E N TS   H E L D   AT   FA I R  VA LU E  T H R O U G H   P R O F I T   O R   LO S S

Income from investments
UK listed dividends
Overseas dividends
Money market dividend
Fixed interest income

Other income
Deposit interest
Interest received from VAT recovery

Total income from investments held at fair value through profit or loss

Total income comprises:
Dividends
Interest

2010
£’000

–
4,612
–
1,151

5,763

5
57

5,825

4,612
1,213

5,825

3 .

I N V E S T M E N T   MA N AG E M E N T,   MA N AG E M E N T   A N D   P E R F O R MA N C E   F E E S

Investment Management fee
Management  fee
Refund of VAT previously paid on management fees
Performance fee accrual

2010
Revenue
£’000

96
37
–
–

133

2010
Capital
£’000

1,828
693
(255)
2,759

5,025

2010
Total
£’000

1,924
730
(255)
2,759

5,158

2009
Revenue
£’000

83
33
–
–

116

2009
Capital
£’000

1,584
628
–
224

2,436

2009
£’000

212
3,594
48
71

3,925

93
–

4,018

3,854
164

4,018

2009
Total
£’000

1,667
661
–
224

2,552

In accordance with the performance fee arrangements described in the Report of the Directors on page 18 no performance fee
was paid during the year ended 31 March 2010 (2009: nil). At the year end a performance fee of £2,759,000 was accrued, in
addition, the performance fee of £224,000 accrued at 31 March 2009 crystalised and become payable post the year end. Of the
£224,000 fee payable, £204,000 is payable to the Investment Manager and £20,000 is payable to the Manager.

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Notes to the Financial Statements (continued)

43

4 . OT H E R   E X P E N S E S

Directors’ remuneration 
Auditors’ remuneration for the audit of the Company’s financial statements
Auditors’ remuneration for other services
Marketing 
ISA and savings scheme expenses 
Registrar 
Custody
Other 

Details of the amounts paid to Directors are included in the Directors’ Remuneration Report on page 33.

5 .   F I N A N C E   C H A R G E S

Finance charges

2010
Revenue
£’000

11

2010
Capital
£’000

212

2010
Total
£’000

223

2009
Revenue
£’000

29

2009
Capital
£’000

543

6 . TAXAT I O N   O N   O R D I N A RY   AC T I V I T I E S

(a) Analysis of charge in year:

UK corporation tax at 28% (2009: 28%)
Tax relief to capital
Overseas taxation

2010
Revenue
£’000

2010
Capital
£’000

303
662

965

(303)
–

(303)

2010
Total
£’000

–
662

662

2009
Revenue
£’000

2009
Capital
£’000

360
506

866

(360)
–

(360)

2010
Revenue
£’000

2009
Revenue
£’000

146
23
15
32
3
56
13
218

506

152
22
4
38
18
41
37
276

588

2009
Total
£’000

572

2009
Total
£’000

–
506

506

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Notes to the Financial Statements (continued)

6 . TAXAT I O N   O N   O R D I N A RY   AC T I V I T I E S   (CO N T I N U E D)

(b) Factors affecting current tax charge for the year
The tax charged for the year is lower than the standard rate of corporation tax in the UK for a large company 28% (2009: 28%). 

The difference is explained below.

Total return before tax

Corporation tax at 28% (2009: 28%)
Non-taxable gains on investments held at fair value 

through profit and loss

Overseas withholding tax not recoverable
Non taxable overseas dividends
Non taxable UK dividend
Expenses charged to capital available to be utilised
Timing differences on overseas dividends
Disallowed expenses

Current tax charge

2010
Revenue
£’000

5,175

1,449

–
662
(1,100)
–
(122)
75
1

965

2010
Capital
£’000

74,889

20,969

(22,435)
–
–
–
1,163
–
–

(303)

2010
Total
£’000

80,064

22,418

(22,435)
662
(1,100)
–
1,041
75
1

662

2009
Revenue
£’000

3,285

920

–
506
–
(59)
(479)
(27)
5

866

2009
Capital
£’000

61,484

17,216

(18,049)
–
–
–
473
–
–

(360)

2009
Total
£’000

64,769

18,136

(18,049)
506
–
(59)
(6)
(27)
5

506

(c) Provision for deferred tax
The Company has not recognised a deferred tax asset of £10,324,000 (2009: £10,996,000) arising as a result of unutilised expenses.
These expenses will only be utilised if the Company generates sufficient taxable profits in the future or if there is a change in the
legislation and capital gains become taxable for investment trust companies. It is considered too uncertain that either of these
will occur and, therefore, no deferred tax asset has been recognised. There is no capital gains tax payable by the Company
because investment trust companies are exempt from this tax.

7 . R E T U R N P E R   S H A R E

The return per share is based in the following figures:
Revenue return
Capital return

Total return

2010
£’000

4,210
75,192

79,402

2009
£’000

2,419
61,844

64,263

Weighted average number of ordinary shares in issue during the year – basic

44,122,846

43,756,755

Revenue return per share
Capital return per share

Total return per share – basic

9.5p
170.5p

180.0p

5.5p
141.4p

146.9p

Weighted average number of shares in issue during the year – diluted

44,122,846

44,764,156

Revenue return per share
Capital return per share

Total return per share – diluted

*

dilution not applicable

9.5p*
170.5p*

180.0p*

5.4p
138.2p

143.6p

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Notes to the Financial Statements (continued)

45

8 .

I N T E R I M   D I V I D E N D

Under UK GAAP, final dividends are not recognised until they are approved by shareholders and interim dividends are not
recognised until they are paid. They are also debited directly from reserves. Amounts recognised as distributable to ordinary
shareholders for the year ended 31 March 2010 were as follows:

Interim dividend in respect of the year ended 31 March 2009
Interim dividend in respect of the year ended 31 March 2008

2010
£’000

1,982
–

1,982

2009
£’000

–
1,344

1,344

In respect of the year ended 31 March 2010, an interim dividend of 8.5p per share (2009: 5.0p per share) has been declared. The
aggregate cost of this dividend based on the number of shares in issue at 21 June 2010 is estimated to be £3,653,000. In
accordance with FRS 21 this dividend will be reflected in the interim accounts for the period ending 30 September 2010. Total
dividends in respect of the financial year, which is the basis on which the requirements of s842 of the Income and Corporation
Taxes Act 1988 are considered, are set out below:

Revenue available for distribution by way of dividend for the year
Dividends for the year ended 31 March

based on 42,979,817 shares in issue as at 21 June 2010.

9 .

I N V E S T M E N TS  

Cost at 1 April 2009
Investment holdings gains/(losses)

at 1 April 2009

Valuation at 1 April 2009

Movement in the year:
Purchases at cost
Sales – proceeds

– realised gains/(losses) on sales

Net movement in investment holding

gains/(losses)

Valuation at 31 March 2010

Cost at 31 March 2010
Investment holding gains

at 31 March 2010

Valuation at 31 March 2010

Listed
investments
£’000

252,165

42,763

294,928

241,009
(231,909)
45,750

26,507

376,285

307,015

69,270

376,285

Unlisted
investments
£’000

1,094

(1,094)

–

6,318
(7)
(1,087)

2,090

7,314

6,318

996

7,314

2010
£’000

4,210
(3,653)

557

OTC
swap

10,031

290

10,321

–
(10,253)
222

(290)

–

–

–

–

Derivatives

Options
£’000

(158)

(796)

(954)

7,574
(8,980)
1,942

1,046

628

378

250

628

2009
£’000

2,419
(1,982)

437

Total
£’000

263,132

41,163

304,295

254,901
(251,149)
46,827

29,353

384,227

313,711

70,516

384,227

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Notes to the Financial Statements (continued)

9 .

I N V E S T M E N TS   (CO N T I N U E D)

Gains on investment

Realised gains based on historical cost – sales
Less: amounts recognised as investment holding gains in previous years

Realised gains based on carrying value at previous Balance Sheet date
Movement in investment holding gains in the year

Gains on investments

2010
£’000

46,827
(40,817)

6,010
70,170

76,180

2009
£’000

35,421
(5,043)

30,378
46,127

76,505

Purchase transaction costs for the year to 31 March 2010 were £467,000 (year ended 31 March 2009: £492,000). These comprise
mainly stamp duty and commission.

Sales transaction costs for the year to 31 March 2010 were £372,000 (year ended 31 March 2009: £367,000). These comprise
mainly commission.

1 0 . D E BTO R S

Amounts due from brokers
Withholding taxation recoverable
VAT recoverable
Prepayments and accrued income

1 1 . C R E D I TO R S

Amounts falling due within one year

Amounts due to brokers
Amounts due to brokers – OTC swap
Amounts due to brokers – purchase of own shares
Stamp duty due on purchase of own shares
Bank loan facility*
Performance fee accrual
Other creditors and accruals

2010
£’000

535
323
37
862

1,757

2010
£’000

–
–
–
4
36,062
2,983
754

39,803

2009
£’000

245
416
33
613

1,307

2009
£’000

100
10,794
608
4
40,183
224
651

52,564

*

The Company’s borrowing requirements are met through the utilisation of a loan facility, repayable on demand, provided by
Goldman Sachs & Co. New York (“Goldman Sachs”). Interest on the facility is charged at the Federal effective rate plus 1 week OIS+
Spread plus 45 basis points. As at 31 March 2010 assets to the value of approximately 140% of the the Company’s debt were held
by Goldman Sachs as collateral.

1 2 . D E R I VAT I V E   F I N A N C I A L   I N S T R U M E N TS

Fair value of call and put options
Fair value of OTC equity swap

See note 9 on pages 45 and 46 for movements in the year.

+
See Glossary on page 62.

2010
£’000

628
–

628

2009
£’000

(954)
10,321

9,367

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Notes to the Financial Statements (continued)

47

1 3 . S H A R E   C A P I TA L

Issued and fully paid:
At 1 April 2009
Ordinary shares bought back and held in treasury
Treasury shares cancelled following 2009 AGM
Ordinary shares bought back for cancellation
Exercise of remaining warrants
Subscription share of 1p
Subscription shares converted to Ordinary shares

At 31 March 2010

Issued and fully paid:
50,576,172 Ordinary shares of 25p
8,992,307 Subscription shares 1p

Ordinary

shares

number

41,361,431
(7,166,763)
–
(1,342,175)
10,745,610
–
738,653

44,336,756

Treasury

shares

number

3,058,050
7,166,763
(3,985,397)
–
–
–
–

6,239,416

Total

Ordinary

shares

in issue

number

44,419,481
–
(3,985,397)
(1,342,175)
10,745,610
–
738,653

50,576,172

Total

Subscription

shares

in issue

number

–
–
–
–
–
9,730,960
(738,653)

8,992,307

£’000

12,644
90

During the year ended 31 March 2010 a total of 8,508,938 shares were bought back by the Company (2009: 4,841,800),
6,239,416 of these were held in treasury at 31 March 2010 (2009: 3,058,050), at a cost of £48,453,000 including expenses of
£337,000 (2009: £24,746,000); 1,342,175 of the shares repurchased were immediately cancelled. In addition, all of the 3,985,397
shares held in treasury at 17 July 2009, date of the Company’s Annual General Meeting, were cancelled in accordance with the
Board’s stated policy.

The final exercise date for the Company’s warrants was 31 July 2009 and all of the 10,745,610 remaining warrants in issue on that
date were converted into shares (on a one for one basis) on 5 August 2009 raising £49,860,000 of additional funds for the
Company.

On 4 September 2009, the Company made bonus issue of subscription shares on the basis of one subscription share for every
five ordinary shares held at that date. The subscription shares have quarterly subscription dates and the following shares were
allotted by the Company as a result of certain holders of the subscription shares exercising their subscription rights during
the year:

42,148 shares were allotted on 13 November 2009 raising £259,000,

696,505 shares were allotted on 3 February 2009m raising £4,276,000,

At the year end there were 8,992,307 subscription shares in issue (2009: 10,745,610 warrants).

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Notes to the Financial Statements (continued)

1 4 . N E T   A S S E T  VA LU E   P E R   S H A R E

Net asset value per share – basic

Net asset value per share – diluted for subscription shares/warrants

2010
£’000

780.8p

752.7p

2009
£’000

635.9p

600.5p

The net asset value per share is based on the assets attributable to equity shareholders of £346,181,000 (2009: £263,017,000) and
on the number of shares in issue at the year end of 44,336,756 (excluding shares held in treasury) (2009: 41,361,431). As at
31 March 2010, there were 8,992,307 subscription shares in issue (2009: 10,745,610 warrants). The diluted net asset value per share
assumes all outstanding subscription shares were exercised at 614p resulting in assets attributable to equity shareholders of
£401,394,000 and on 53,329,063 shares (2009: assumed all outstanding warrants were exercised at 464p resulting in assets
attributable to shareholders of £312,877,000 and on 52,107,041 shares). As at 31 March 2010 the Company held 6,239,416 shares
in treasury (2009: 3,058,050). The treasury shares were not dilutive at 31 March 2010.

1 5 . R E CO N C I L I AT I O N   O F   O P E R AT I N G   R E T U R N  TO   N E T   C A S H   O U T F LO W   F R O M

O P E R AT I N G AC T I V I T I E S

Gains before finance costs and taxation
Less: capital gain before finance costs and taxation

Revenue return before finance costs and taxation
Expenses charged to capital
Increase in accrued income
(Increase)/decrease in other debtors
Increase in creditors and accruals
Net taxation suffered on investment income

Net cash inflow/(outflow) from operating activities

2010
£’000

80,287
(75,101)

5,186
(5,025)
(249)
(4)
2,862
(662)

2,108

1 6 . R E CO N C I L I AT I O N   O F   N E T   C A S H   F LO W   M O V E M E N T  TO   M O V E M E N T   I N   N E T D E B T

2009
£’000

65,341
(62,027)

3,314
(2,436)
(422)
3
220
(740)

(61)

2009
£’000

(35,950)
(12,042)
14,813

(33,179)
2,975

(30,204)

2010
£’000

(9,804)
3,946
–

(5,858)
(30,204)

(36,062)

Increase in net debt resulting from cashflows
Exchange movements
Decrease in short term loans/bank overdraft

Movement in net debt in the year
Net (debt)/funds at start of year

Net debt at end of year

Represented by:

Net bank overdraft/cash at bank

Net debt

At 1 April
2009
£’000

(30,204)

(30,204)

Cash flows
£’000

(9,804)

(9,804)

Exchange
movements
£’000

3,946

3,946

At 31 March
2010
£’000

(36,062)

(36,062)

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Notes to the Financial Statements (continued)

49

1 7 . R E L AT E D   PA R T I E S
Details of the relationship between the Company, Frostrow Capital LLP and OrbiMed Capital LLC are disclosed in the Report of
the Directors on pages 17 and 18. Samuel D Isaly is a Director of the Company, as well as Managing Partner of the Company’s
Investment Manager, OrbiMed Capital LLC; also a number of the partners at OrbiMed Capital LLC have a minority financial interest
totalling 20% in Frostrow Capital LLP. During the year ended 31 March 2010, OrbiMed Capital LLC received £1,924,000 in respect
of Investment Management fees, of which £554,000 was outstanding at the year end. In addition an amount of £204,000 was
outstanding in respect of performance fees which crystalised at 31 March 2010.

1 8 . F I N A N C I A L   I N S T R U M E N TS’ E X P O S U R E  TO   R I S K   A N D   R I S K   MA N AG E M E N T   P O L I C I E S

The Company’s financial instruments comprise securities and other investments, derivative instruments, cash balances, loans,
debtors and creditors that arise directly from its operations.

As an investment trust, the Company invests in equities  and other investments for the long term so as to secure its investment
objective as stated on page 14. In pursuing its investment objective, the Company is exposed to a variety of risks that could result
in a reduction in the Company’s net assets.

The main risks that the Company faces arising from its financial instruments are:

(i) market risk (including foreign currency risk, interest rate risk and other price risk)

(ii)

liquidity risk

(iii) credit risk

These risks and the Directors’ approach to the management of them, are set out in the Report of Directors on pages 15 and 16
and have not changed from the previous accounting period. The Investment Manager, in close co-operation with the Board of
Directors, co-ordinates the Company’s risk management.

(i) Market risk:
The Company’s portfolio is exposed to market price fluctuations which are monitored by the Investment Manager in pursuance
of the investment objective. Further information on the portfolio is set out on page 12.

Management of risk:
Derivative instruments are used to mitigate market price risk, the following option strategies or a combination of such have been
used during the financial year:

•

•

•

•

Buy calls: provides leveraged long exposure, facilitates exposure while minimising capital at risk.

Buy puts: provides leveraged protection, facilitates exposure while minimising capital at risk.

Sell calls: against an existing position, provides partial protection from a decline in stock price; facilitates commitment to an
exit strategy and exit price that is consistent with fundamental analysis.

Sell puts: provides an effective entry price at which to add to an existing position, or provides an effective entry price at which
to initiate a new position.

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50

Notes to the Financial Statements (continued)

18. FINANCIAL INSTRUMENTS’ EXPOSURE TO RISK AND RISK MANAGEMENT POLICIES (CONTINUED)

(a) Foreign Currency risk
A significant proportion of the Company’s portfolio is denominated in currencies other than sterling (the Company’s functional
currency, and the currency in which it reports its results). As a result, movements in exchange rates can significantly affect the
sterling value of those items.

Rate of exchange against sterling at 31 March

U.S. dollar
Japanese yen
Swiss franc
Euro/Danish kroner

2010

1.5169
141.7392
1.5967
1.1211

2009

1.4334
141.5720
1.6298
1.0796

Foreign currency exposure and sensitivity
The fair values of the Company’s monetary items that are denominated in foreign currency as at 31 March 2010 are shown below:

U.S. dollar
Swiss franc
Japanese yen
Euro/Danish kroner
Hong Kong dollar

2010
Current
assets
£’000

2,004
323
–
–
–

2,327

2010
Current
liabilities
£’000

(35,990)
–
–
–
–

(35,990)

2010

investments
£’000

305,223
45,731
22,347
1,324
9,602

384,227

2009
Current
assets
£’000

9,619
–
147
–
–

9,766

2009
Current
liabilities
£’000

(52,031)
–
–
–
–

(52,031)

2009

investments
£’000

209,994
28,976
25,464
7,167
–

271,601

Management of risk:
The Investment Manager and Manager monitor the Company’s exposure to foreign currencies on a daily basis and report to the
Board on a regular basis. The Investment Manager does not hedge against foreign currency movements, but takes account of the
risk when making investment decisions.

Foreign currency borrowing facilities are available and are currently being utilised, to limit the Company’s exposure to anticipated
future changes in exchange rates, which might otherwise adversely affect the value of portfolio investments.

Income denominated in foreign currencies is converted into sterling on receipt. The Company does not use financial instruments
to mitigate the currency exposure in the period between the time that the income is included in the financial statements and its
receipt.

Foreign currency sensitivity
The following table details the sensitivity of the Company’s profit or loss after taxation for the year and shareholders’ funds to a
10% increase and decrease in sterling against the U.S. dollar (2009: 30% increase and decrease), a 5% increase and decrease in
sterling against the Japanese yen (2009: 30% increase and decrease), and a 5% increase and decrease in sterling against the Swiss
franc (2009: 20% increase and decrease).

These percentages have been determined based on market volatility in exchange rates over the previous 12 months. The
sensitivity analysis is based on the Company’s foreign currency financial instruments held at each Balance Sheet date.

Sterling depreciates
Sterling appreciates

2010
USD
£’000

29,910
(24,471)

2010
YEN
£’000

1,180
(1,069)

2010
CHF
£’000

2,456
(2,228)

2009
USD
£’000

76,283
(41,084)

2009
YEN
£’000

10,899
(5,871)

2009
CHF
£’000

7,394
(4,918)

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Notes to the Financial Statements (continued)

51

18. FINANCIAL INSTRUMENTS’ EXPOSURE TO RISK AND RISK MANAGEMENT POLICIES (CONTINUED)

(b) Interest rate risk
Interest rate movement may affect:

–

–

–

the interest payable on the Company’s variable rate borrowings;

the level of income receivable from floating rate securities and cash at bank and on deposit;

the fair value of investments of fixed interest securities.

Management of the risk
The possible effects on fair value and cash flows that could arise as a result of changes in interest rates are taken into account
when making investment decisions and borrowing under the multicurrency loan facility.

The Company, generally, does not hold significant cash balances (except when required for collateral against the Company’s
derivative positions), with short term borrowing being used when required.

Interest rate exposure
The Company has a loan facility with Goldman Sachs which is repayable on demand. £35,992,000 was drawn down under this
facility at 31 March 2010. The exposure of financial assets and liabilities to floating interest rates, giving cash flow interest rate risk
when rates are re-set, is shown below.

Floating rate
The floating interest rate exposure of the financial assets and financial liabilities to interest rate risk at 31 March 2010 in respect of
cash was nil (2009: £9,979,000). At 31 March 2010 there was an overdraft position with Bank of New York Mellon of £70,000
(2009: nil) and a bank overdraft position at Goldman Sachs of £35,992,000 (2009: £40,183,000).

Fixed rate
In the year to 31 March 2010, the Company held 8.2% of the portfolio in fixed interest securities. This percentage is deemed not
to be material and accordingly no sensitivity analysis has been presented.

(c) Other price risk
Other price risk may affect the value of the Company’s investments. If market prices at the Balance Sheet date had been 25%
higher or lower (2009: 20% higher or lower) while all other variables remained constant, the revenue return would have
decreased/increased by £43,000 (2009: £22,000), and the capital return would have increased/decreased by £95,187,000
(2009: £60,273,000) and the return on equity would have increased/decreased by £95,230,000. The calculations are based on the
portfolio valuations as at the respective balance sheet dates and are not representative of the year as a whole.

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Notes to the Financial Statements (continued)

18. FINANCIAL INSTRUMENTS’ EXPOSURE TO RISK AND RISK MANAGEMENT POLICIES (CONTINUED)

(ii) Liquidity risk
This is the risk that the Company will encounter difficulty in meeting obligations associated with financial liabilities.

Management of the risk
Liquidity risk is not significant as the majority of the Company’s assets are investments in quoted equities and other quoted
securities that are readily realisable. The Company has a loan facility repayable on demand with Goldman Sachs.

Interest on the facility is charged at the Federal effective rate plus 1 week OIS Spread plus 45 basis points.

In order to ensure diversification within the portfolio, the Board gives guidance to the Investment Manager concerning exposure
limits to individual companies. Geographical and sectoral exposure are also reviewed regularly by the Directors.

Liquidity exposure
Contractual maturities of the financial liabilities as at 31 March 2010, based on the earliest date on which payment can be
required are as follows:

31 March 2010

Current liabilities:
Borrowings under the loan facility
Amounts due to brokers and accruals

3 months
or less
£’000

36,062
982

37,044

*
assuming the performance fee accrued at 31 March 2010 crystalises at 31 March 2011.

31 March 2009

Current liabilities:
Borrowings under the loan facility
Amounts due to brokers and accruals

3 months
or less
£’000

40,183
1,363

41,546

2010

Not more than
one year
£’000

–
2,759*

2,759

2009
Not more
than one year
£’000

–
11,018

11,018

Total
£’000

36,062
3,741

39,803

Total
£’000

40,183
12,381

52,564

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Notes to the Financial Statements (continued)

53

18. FINANCIAL INSTRUMENTS’ EXPOSURE TO RISK AND RISK MANAGEMENT POLICIES (CONTINUED)

(iii) Credit risk
The failure of the counterparty to a transaction to discharge its obligations under that transaction could result in the Company
suffering a loss.

The carrying amounts of financial assets best represent the maximum credit risk at the Balance Sheet date. The Company’s listed
investments are held on its behalf by Goldman Sachs acting as the Company’s custodian.

Bankruptcy or insolvency of a custodian may cause the Company’s rights with respect to securities held by that custodian to be
delayed, however, the Board monitors the Company’s risk to its custodians by reviewing continuously their internal control reports
and their credit ratings.

Certain of the Company’s assets are held by Goldman Sachs as collateral for the loan provided by them to the Company. Such
assets held by Goldman Sachs are available for rehypothecation.†

Management of the risk
The risk is not significant, and is managed as follows:

•

•

•

by only dealing with brokers which have been approved by OrbiMed Capital LLC and banks with high credit ratings;

by setting limits to the maximum exposure to any one counterparty at any time; and

by monitoring the assets subject to rehypothecation†.

† See Glossary on page 62. 

Credit risk exposure

Fixed interest securities and convertibles
M&A Basket – OTC equity swap

Current assets:
Other receivables (amounts due from brokers, dividends 

and interest receivable)
Cash at bank and on deposit*

Includes cash held as collateral.
*

2010
Balance
Sheet
£’000

31,785
–

2,385
–

2009
Balance
Sheet
£’000

2,344
10,321

1,307
9,979

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Notes to the Financial Statements (continued)

18. FINANCIAL INSTRUMENTS’ EXPOSURE TO RISK AND RISK MANAGEMENT POLICIES (CONTINUED)

Company’s hierarchy as quoted in note 1b on page 40.

As of 31 March 2010

Assets/(liabilities)
Financial investments designated at 
fair value through profit or loss

Fair value of derivative financial instruments

Assets measured at fair value 

Level 1
£’000

376,285

–

376,285

Level 2
£’000

–

628

628

Level 3
£’000

7,314

–

7,314

Total 
£’000

383,599

628

384,227

As at 31 March 2010, the put and call options have been classified as level two and the investment in the unquoted Convertible
Preferred Equity Certificates (CPEC) has been classed as level three. All of the remaining investments have been classified as
level one.

As of 31 March 2009

Assets/(liabilities)
Financial investments designated at 
fair value through profit or loss

Fair value of derivative financial instruments

Assets measured at fair value 

Level 1
£’000

294,928

–

294,928

Level 2
£’000

–

9,367

9,367

Level 3
£’000

Total 
£’000

–

–

–

294,928

9,367

304,295

Level 3 Reconciliation

At 31 March 2010

Purchases at cost
Total gains included in gains on investments in the income statement:
– on assets held at the end of the year

Closing balance

2010
Equity
investments
£’000

6,318

996

7,314

Level 3 valuation techniques used by the Company are explained in the accounting policies in note 1b.

Fair value of financial assets and financial liabilities
The fair value of the financial assets and financial liabilities are either carried in the Balance Sheet at their fair value (investments
and derivatives) or the Balance Sheet amount is a reasonable approximation of fair value (due from brokers, dividends and
interest receivable, due to brokers, accrual, cash at bank, bank overdraft and amounts due under the loan facility).

Capital management policies and procedures
The Company’s capital management objectives are to ensure that it will be able to continue as a going concern and to maximise
the income and capital return to its equity shareholders through an appropriate level of gearing.

The Board’s policy is to limit gearing to the lower of £70m and 20% of the Company’s net assets.

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Notes to the Financial Statements (continued)

55

18. FINANCIAL INSTRUMENTS’ EXPOSURE TO RISK AND RISK MANAGEMENT POLICIES (CONTINUED)

The capital structure of the Company consists of the equity share capital, retained earnings and other reserves as disclosed on the
Balance Sheet on page 38.

Gearing for this purpose is defined as net debt as a percentage of total net assets. As at 31 March 2010 the gearing percentage of
the Company was 10.4% (2009: 11.5%).

The Board with the assistance of the Investment Manager monitors and reviews the broad structure of the Company’s capital on
an ongoing basis. This includes a review of:

–

–

–

–

the planned level of gearing, which takes into account the Investment Manager’s view of the market;

the need to buy back equity shares, either for cancellation or to hold in treasury, in light of any share price discount to net
asset value per share in accordance with the Company’s share buyback policy;

the need for new issues of equity shares, including issues from treasury; and

the extent to which revenue in excess of that which is required to be distributed should be retained.

The Company’s objectives, policies and processes for managing capital are unchanged from the preceding accounting period.

The Company is also subject to several externally imposed capital requirements and are as follows:

–

–

as a public company, the Company has a minimum share capital of £50,000; and

in order to be able to pay dividends out of profits available for distribution, the Company has to be able to meet one of the
two capital restriction tests imposed on investment companies by company law.

These requirements are unchanged since last year and the Company has complied with them.

1 9 . C A P I TA L   R E S E R V E

At 31 March 2009
Transfer on disposal of investments
Net gains on investments
Expenses charged to capital
Subscription shares issued less issue costs
Shares purchased including expenses
Exchange gain on currency balances

At 31 March 2010

Capital Reserve –
Other
£’000

Capital Reserve –
Investment
Holding Gains
£’000

77,546
40,817
6,010
(4,934)
(288)
(48,453)
3,946

74,644

41,163
(40,817)
70,170
–
–
–
–

70,516

Total
£’000

118,709
–
76,180
(4,934)
(288)
(48,453)
3,946

145,160

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Notice of Annual General Meeting

Notice is hereby given that the Annual General Meeting of Finsbury Worldwide Pharmaceutical Trust PLC will be held at the Barber-
Surgeons’ Hall, Monkwell Square, Wood Street, London, EC2Y 5BL on Thursday, 15 July 2010 from 12 noon for the following purposes:

O R D I N A RY   B U S I N E S S
1.

To receive and, if thought fit, to accept the Audited Accounts and the Report of the Directors for the year ended 31 March 2010

2.

3.

4.

5.

6.

7.

8.

To re-elect Ms Jo Dixon as a Director of the Company

To re-elect Mr Paul Gaunt as a Director of the Company

To re-elect Professor Duncan Geddes as a Director of the Company

To re-elect Mr Samuel D Isaly as a Director of the Company

To re-elect Mr Anthony Townsend as a Director of the Company

To re-appoint Ernst & Young LLP as the Company’s Auditors and to authorise the Directors to determine their remuneration

To approve the Directors’ Remuneration Report for the year ended 31 March 2010

S P E C I A L   B U S I N E S S
To consider, and if thought fit, pass the following resolutions of which resolutions 10, 11, 12, 14 and 16 will be proposed as special
resolutions:

Authority to Allot Shares
9.

THAT in substitution for all existing authorities the Directors be and are hereby generally and unconditionally authorised in
accordance with section 551 of the Companies Act 2006 (the “Act”) to exercise all powers of the Company to allot relevant
securities (within the meaning of section 551 of the Act) up to a maximum aggregate nominal amount of £1,074,495 (being
10% of the issued share capital of the Company at 21 June 2010) and representing 4,297,982 shares of 25 pence each (or, if less,
the number representing 10% of the issued share capital of the Company at the date at which this resolution is passed),
provided that this authority shall expire at the conclusion of the Annual General Meeting of the Company to be held in 2011 or
15 months from the date of passing this resolution, whichever is the earlier, unless previously revoked, varied or renewed, by the
Company in General Meeting and provided that the Company shall be entitled to make, prior to the expiry of such authority, an
offer or agreement which would or might require relevant securities to be allotted after such expiry and the Directors may allot
relevant securities pursuant to such offer or agreement as if the authority conferred hereby had not expired.

Disapplication of Pre-emption Rights
10. THAT in substitution of all existing powers (but in addition to any power conferred on them by resolution 11 set out in the

notice convening the Annual General Meeting at which this resolution is proposed (“Notice of Annual General Meeting”)) the
Directors be and are hereby generally empowered pursuant to Section 570 of the Companies Act 2006 (the “Act”) to allot equity
securities (within the meaning of Section 560 of the Act) for cash pursuant to the authority conferred on them by resolution 9
set out in the Notice of Annual General Meeting or otherwise as if Section 561(1) of the Act did not apply to any such allotment:

(a) pursuant to an offer of equity securities open for acceptance for a period fixed by the Directors where the equity
securities respectively attributable to the interests of holders of shares of 25p each in the Company (“Shares”) are
proportionate (as nearly as may be) to the respective numbers of Shares held by them but subject to such exclusions or
other arrangements in connection with the issue as the Directors may consider necessary, appropriate or expedient to
deal with equity securities representing fractional entitlements or to deal with legal or practical problems arising in any
overseas territory, the requirements of any regulatory body or stock exchange, or any other matter whatsoever; and 

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Notice of Annual General Meeting (continued)

57

(b) provided that (otherwise than pursuant to sub-paragraph (a) above) this power shall be limited to the allotment of

equity securities up to an aggregate nominal value of £1,074,495, being 10% of the issued share capital of the Company
as at 21 June 2010 and representing 4,297,982 Shares or, if changed, the number representing 10% of the issued share
capital of the Company at the date of the meeting at which this resolution is passed, and provided further that (i) the
number of equity securities to which this power applies shall be reduced from time to time by the number of treasury
shares which are sold pursuant to any power conferred on the Directors by resolution 11 set out in the Notice of Annual
General Meeting and (ii) no allotment of equity securities shall be made under this power which would result in Shares
being issued at a price which is less than the net asset value per Share as at the latest practicable date before such
allotment of equity securities as determined by the Directors in their reasonable discretion,

and such power shall expire at the conclusion of the next Annual General Meeting of the Company after the passing of this
resolution or 15 months from the date of passing this resolution, whichever is earlier, unless previously revoked, varied or renewed
by the Company in general meeting and provided that the Company shall be entitled to make, prior to the expiry of such
authority, an offer or agreement which would or might otherwise require equity securities to be allotted after such expiry and the
Directors may allot equity securities pursuant to such offer or agreement as if the power conferred hereby had not expired.

11. THAT in substitution of all existing powers (but in addition to any power conferred on them by resolution 10 set out in the
Notice of Annual General Meeting) the Directors be and are hereby generally empowered pursuant to Section 570 of the
Companies Act 2006 (the “Act”) to sell relevant shares (within the meaning of Section 560 of the Act) if, immediately before
the sale, such shares are held by the Company as treasury shares (as defined in Section 724 of the Act (“treasury shares”)), for
cash as if Section 561(1) of the Act did not apply to any such sale provided that:

(a) where any treasury shares are sold pursuant to this power at a discount to the then prevailing net asset value of

ordinary shares of 25p each in the Company (“Shares”), such discount must be (i) lower than the discount to the net
asset value per Share at which the Company acquired the Shares which it then holds in treasury and (ii) not greater than
5% to the prevailing net asset value per Share at the latest practicable time before such sale (and for this purpose the
Directors shall be entitled to determine in their reasonable discretion the discount to their net asset value at which such
Shares were acquired by the Company and the net asset value per Share at the latest practicable time before such
Shares are sold pursuant to this power); and 

(b)

this power shall be limited to the sale of relevant shares having an aggregate nominal value of £1,074,495, being 10% of
the issued share capital of the Company as at 21 June 2010 and representing 4,297,982 Shares or, if changed, the
number representing 10% of the issued share capital of the Company at the date of the meeting at which this
resolution is passed, and provided further that the number of relevant shares to which power applies shall be reduced
from time to time by the number of Shares which are allotted for cash as if Section 561(1) of the Act did not apply
pursuant to the power conferred on the Directors by resolution 10 set out in the Notice of Annual General Meeting, 

and such power shall expire at the conclusion of the next Annual General Meeting of the Company after the passing of this
resolution or 15 months from the date of passing this resolution, whichever is earlier, unless previously revoked, varied or
renewed by the Company in General Meeting and provided that the Company shall be entitled to make, prior to the expiry of
such authority, an offer or agreement which would or might otherwise require treasury shares to be sold after such expiry and
the Directors may sell treasury shares pursuant to such offer or agreement as if the power conferred hereby had not expired.

Authority to Repurchase Ordinary Shares
12. THAT the Company be and is hereby generally and unconditionally authorised in accordance with section 701 of the

Companies Act 2006 (the “Act”) to make one or more market purchases (within the meaning of section 693(4) of the Act) of
ordinary shares of 25 pence each in the capital of the Company (“Shares”) provided that:

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Notice of Annual General Meeting (continued)

(a)

the maximum aggregate number of Shares authorised to be purchased is 6,442,675 (representing approximately 14.99% of
the issued share capital of the Company at the date of the notice convening the meeting at which this resolution is
proposed);

(b)

the minimum price (exclusive of expenses) which may be paid for a Share is 25 pence;

(c)

(d)

(e)

the maximum price (exclusive of expenses) which may be paid for a Share is an amount equal to the greater of (i) 105%
of the average of the middle market quotations for a Share as derived from the Daily Official List of the London Stock
Exchange for the five business days immediately preceding the day on which that Share is purchased and (ii) the higher
of the price of the last independent trade in shares and the highest then current independent bid for shares on the
London Stock Exchange as stipulated in Article 5(1) of Regulation No. 2233/2003 of the European Commission
(Commission Regulation of 22 December 2003 implementing the Market Abuse Directive as regards exemptions for
buyback programmes and stabilisation of financial instruments);

the authority hereby conferred shall expire at the conclusion of the Annual General Meeting of the Company to be held
in 2011 or, if earlier, on the expiry of 15 months from the date of the passing of this resolution unless such authority is
renewed prior to such time; and

the Company may make a contract to purchase Shares under this authority before the expiry of such authority which
will or may be executed wholly or partly after the expiration of such authority, and may make a purchase of Shares in
pursuance of any such contract.

Electronic Communication
13. THAT the Company be authorised, subject to and in accordance with the provisions of the Companies Act 2006 and the

articles of association of the Company (as from time to time amended or varied) to send, convey or supply all types of
notices, documents or information to the members by means of electronic equipment (such term is defined in the Financial
Services Authority’s Disclosure and Transparency Rules) for the processing (including, without limitation, by means of digital
compression) storage and transmission of data, employing wires, radio optical technologies, or any other electromagnetic
means, including without limitation, by making such notices, documents or information available on a website.

General Meetings
14. THAT as permitted by the EU Shareholders’ Rights Directive (2007/36/EC) any General Meeting of the Company (other than the

Annual General Meeting of the Company) shall be called by notice of at least 14 clear days in accordance with the provisions
of the Articles of Association of the Company provided that the authority shall expire on the conclusion of the next Annual
General Meeting of the Company, or, if earlier, on the expiry 15 months from the date of the passing of the resolution.

Change to Investment Policy

15. THAT the proposed revised investment policy and benchmark set out on pages 21 and 22 of the Company’s annual report

and accounts dated 21 June 2010, a copy of which marked “A” and signed for the purpose of identification by the Chairman of
the Meeting and produced to the Meeting, be and it is hereby approved and adopted with immediate effect as the
Company’s investment policy in place of the Company’s existing investment policy.

Change of the Company’s name

16. THAT the name of the Company be changed to Worldwide Healthcare Trust PLC.

By order of the Board

Frostrow Capital LLP
Company Secretary
21 June 2010

Registered Office:
One Wood Street
London EC2V 7WS

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Notice of Annual General Meeting (continued)

59

Notes
1. Members are entitled to appoint a proxy to exercise all or any of their rights to attend and to speak and vote on their behalf at the meeting.
A shareholder may appoint more than one proxy in relation to the meeting provided that each proxy is appointed to exercise the rights
attached to a different share or shares held by that shareholder. A proxy need not be a shareholder of the Company. A proxy form which
may be used to make such appointment and give proxy instructions accompanies this notice.

2.

3.

4.

5.

6.

7.

8.

9.

A vote withheld is not a vote in law, which means that the vote will not be counted in the calculation of votes for or against the resolutions.
If no voting indication is given, a proxy may vote or abstain from voting at his/her discretion. A proxy may vote (or abstain from voting) as he
or she thinks fit in relation to any other matter which is put before the meeting.

To be valid any proxy form or other instrument appointing a proxy must be completed and signed and received by post or (during normal
business hours only) by hand at Capita Registrars, PXS, 34 Beckenham Road, Beckenham, Kent BR3 4TU no later than 12 noon on 13 July 2010.

In the case of a member which is a company, the instrument appointing a proxy must be executed under its seal or signed on its behalf by a
duly authorised officer or attorney or other person authorised to sign. Any power of attorney or other authority under which the instrument
is signed (or a certified copy of it) must be included with the instrument.

The return of a completed proxy form, other such instrument or any CREST Proxy Instruction (as described below) will not prevent a
shareholder attending the meeting and voting in person if he/she wishes to do so.

Any person to whom this notice is sent who is a person nominated under section 146 of the Companies Act 2006 to enjoy information rights (a
“Nominated Person”) may, under an agreement between him/her and the shareholder by whom he/she was nominated, have a right to be
appointed (or have someone else appointed) as a proxy for the meeting. If a Nominated Person has no such proxy appointment right or does not
wish to exercise it, he/she may, under any such agreement, have a right to give instructions to the shareholder as to the exercise of voting rights.

The statement of the rights of shareholders in relation to the appointment of proxies in paragraphs 1 and 3 above does not apply to
Nominated Persons. The rights described in these paragraphs can only be exercised by shareholders of the Company.

Pursuant to regulation 41 of the Uncertificated Securities Regulations 2001, only shareholders registered on the register of members of the
Company (the “Register of Members”) at 5.30 p.m. on 13 July 2010 (or, in the event of any adjournment, on the date which is two days before
the time of the adjourned meeting) will be entitled to attend and vote or be represented at the meeting in respect of shares registered in
their name at that time. Changes to the Register of Members after that time will be disregarded in determining the rights of any person to
attend and vote at the meeting.

As at 21 June 2010 (being the last business day prior to the publication of this notice) the Company’s issued share capital consists of
42,979,817 ordinary shares, carrying one vote each. Therefore, the total voting rights in the Company as at 21 June 2010 are 42,979,817.

10. CREST members who wish to appoint a proxy or proxies through the CREST electronic proxy appointment service may do so by using the
procedures described in the CREST Manual. CREST Personal Members or other CREST sponsored members, and those CREST members who
have appointed a service provider(s), should refer to their CREST sponsor or voting service provider(s), who will be able to take the
appropriate action on their behalf.

11.

In order for a proxy appointment or instruction made using the CREST service to be valid, the appropriate CREST message (a “CREST Proxy
Instruction”) must be properly authenticated in accordance with the specifications of Euroclear UK and Ireland Limited (“CRESTCo”), and must
contain the information required for such instruction, as described in the CREST Manual. The message, regardless of whether it constitutes
the appointment of a proxy or is an amendment to the instruction given to a previously appointed proxy must, in order to be valid, be
transmitted so as to be received by the issuer’s agent (ID RA10) no later than 48 hours before the time appointed for holding the meeting.
For this purpose, the time of receipt will be taken to be the time (as determined by the timestamp applied to the message by the CREST
Application Host) from which the issuer’s agent is able to retrieve the message by enquiry to CREST in the manner prescribed by CREST. After
this time any change of instructions to proxies appointed through CREST should be communicated to the appointee through other means.

12. CREST members and, where applicable, their CREST sponsors, or voting service providers should note that CRESTCo does not make available
special procedures in CREST for any particular message. Normal system timings and limitations will, therefore, apply in relation to the input of
CREST Proxy Instructions. It is the responsibility of the CREST member concerned to take (or, if the CREST member is a CREST personal
member, or sponsored member, or has appointed a voting service provider, to procure that his CREST sponsor or voting service provider(s)
take(s)) such action as shall be necessary to ensure that a message is transmitted by means of the CREST system by any particular time. In
this connection, CREST members and, where applicable, their CREST sponsors or voting system providers are referred, in particular, to those
sections of the CREST Manual concerning practical limitations of the CREST system and timings.

13.

The Company may treat as invalid a CREST Proxy Instruction in the circumstances set out in Regulation 35(5)(a) of the Uncertificated
Securities Regulations 2001.

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Notice of Annual General Meeting (continued)

14.

In the case of joint holders, where more than one of the joint holders purports to appoint a proxy, only the appointment submitted by the
most senior holder will be accepted. Seniority is determined by the order in which the names of the joint holders appear in the Register of
Members in respect of the joint holding (the first named being the most senior).

15. Members who wish to change their proxy instructions should submit a new proxy appointment using the methods set out above. Note that

the cut-off time for receipt of proxy appointments (see above) also applies in relation to amended instructions; any amended proxy
appointment received after the relevant cut-off time will be disregarded.

16. Members who have appointed a proxy using the hard-copy proxy form and who wish to change the instructions using another hard-copy

form, should contact Capita Registrars on 0871 664 0300 (calls cost 10p per minute plus network extras).

17.

18.

19.

If a member submits more than one valid proxy appointment, the appointment received last before the latest time for the receipt of proxies
will take precedence.

In order to revoke a proxy instruction, members will need to inform the Company. Members should send a signed hard copy notice clearly
stating their intention to revoke a proxy appointment to Capita Registrars, PXS, 34 Beckenham Road, Beckenham, Kent BR3 4TU. 

In the case of a member which is a company, the revocation notice must be executed under its common seal or signed on its behalf by an
officer of the company or an attorney for the company. Any power of attorney or any other authority under which the revocation notice is
signed (or a duly certified copy of such power of attorney) must be included with the revocation notice. If a member attempts to revoke
their proxy appointment but the revocation is received after the time for receipt of proxy appointments (see above) then, subject to
paragraph 4, the proxy appointment will remain valid.

LO C AT I O N   O F  T H E   A N N UA L   G E N E R A L   M E E T I N G

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How to Invest
Alliance Trust Savings Limited

S AV I N G S   P L A N
The Company participates in the Alliance Trust Savings Limited Investment Trust Savings Plan, which facilities both regular
monthly investments and occasional lump sum investments in the Company’s shares. Shareholders who would like information
on the Savings Plan should call Alliance Trust Savings Limited on 01382 573737. Calls to this number are recorded for monitoring
purposes and are charged at local rates, non-BT line charges may vary.

I N D I V I D UA L   S AV I N G S   ACCO U N TS   ( “ I S A” )
ISAs are a tax-efficient method of investment, introduced by the Government. Investors will have the opportunity to invest in the
Company up to £10,200 in the current tax year when they subscribe to a Stocks and Shares ISA.

Capita Registrars – Share Dealing Service

A quick and easy share dealing service is available to existing shareholders through the Company’s Registrar, Capita Registrars, to
either buy or sell shares. An online and telephone dealing facility provides an easy to access and simple to use service.

Type of trade
Share certificates

Online
1% of the value of the deal
(Minimum £20.00, max £75.00)

Telephone
1.5% of the value of the deal
(Minimum £25.00, max £102.50)

There is no need to pre-register and there are no complicated forms to fill in. The online and telephone dealing service allows you
to trade ‘real time’ at a known price which will be given to you at the time you give your instruction.

To deal online or by telephone all you need is your surname, shareholder reference number, full postcode and your date of birth.
Your shareholder reference number can be found on your latest statement or certificate where it will appear as either a ‘folio
number’ or ‘investor code’. Please have the appropriate documents to hand when you log on or call, as this information will be
needed before you can buy or sell shares.

For further information on this service please contact: 

www.capitadeal.com (online dealing) or 0871 664 0446† (telephone dealing)

†
Calls cost 10p per minute plus network extras and may be recorded for training purposes. Lines are open from 8.00 a.m. to 4.30 p.m. Monday to Friday.

R I S K  WA R N I N G S
–
–

Past performance is no guarantee of future performance.
The value of your investment and any income from it may go down as well as up and you may not get back the amount
invested. This is because the share price is determined by the changing conditions in the relevant stockmarkets in which the
Company invests and by the supply and demand for the Company’s shares.

– As the shares in an investment trust are traded on a stockmarket, the share price will fluctuate in accordance with supply and
demand and may not reflect the underlying net asset value of the shares; where the share price is less than the underlying
value of the assets, the difference is known as the ‘discount’. For these reasons, investors may not get back the original amount
invested.

– Although the Company’s financial statements are denominated in sterling, it may invest in stocks and shares that are
denominated in currencies other than sterling and to the extent they do so, they may be affected by movements in
exchange rates. As a result, the value of your investment may rise or fall with movements in exchange rates.
Investors should note that tax rates and reliefs may change at any time in the future.
The value of ISA tax advantages will depend on personal circumstances. The favourable tax treatment of ISAs may not be
maintained.

–
–

The information on this page has been issued and approved by Frostrow Capital LLP, authorised and regulated in the UK by the
Financial Services Authority.

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62

Glossary

I N V E S T M E N T  T R U S T  T E R M S

Diluted Net Asset Value
This is a method of calculating the net asset value (“NAV”) of a
company that has issued, and has outstanding, convertible
loan stocks, warrants or options. The calculation assumes that
the holders have exercised their right to convert or subscribe,
thus increasing the number of shares among which the assets
are divided. 

Discount or Premium
A description of the situation when the share price is lower or
higher than the NAV per share. The size of the discount or
premium is calculated by subtracting the share price from the
NAV per share and is usually expressed as a percentage (%) of
the NAV per share. If the share price is higher than the NAV per
share, this situation is called a premium.

Gearing
Also known as leverage, particularly, in the USA. The term used
to describe the process of borrowing money for investment
purposes in the expectation that the returns on the
investments purchased using the borrowings exceed the costs
of those borrowings. 

NAV per share (pence)
Net asset value per share is shareholders’ funds expressed as an
amount per share. Shareholders’ funds are the total value of all
of the Company’s assets, at current fair value, having deducted
all prior charges.

NAV Total Return
The theoretical total return on shareholders’ funds per share,
including the assumed £100 original investment at the
beginning of the period specified, reflecting the change in
NAV assuming that dividends paid to shareholders were
reinvested at NAV at the time the shares were quoted ex-
dividend. A way of measuring investment management
performance of investment trusts which is not affected by
movements in discounts/premiums. 

OIS (Overnight Indexed Swap)
Overnight indexed swap is an interest rate swap where the
periodic floating rate of the swap is equal to the geometric
average of an overnight index over every day of the payment
period.

Rehypothecation
The pledging of securities or other assets as collateral to secure
a loan such as a debit balance in a margin account. Assets
subject to rehypothecation are protected by relevant U.S. SEC
Rules.

Total Assets
Total assets less current liabilities before deducting prior
charges. Prior charges include all loans for investment
purposes.

Total Expense Ratio
The total expense ratio is calculated by taking the Company’s
expenses and dividing by the average net asset value of the
Company over the year.

Treasury Shares
Shares previously issued by a company that have been bought
back from shareholders to be held by the company for
potential sale or cancellation at a later date.

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Company Information

D I R E C TO R S
Martin Smith (Chairman)
Josephine Dixon
Paul Gaunt
Professor Duncan Geddes
Dr David Holbrook
Samuel D Isaly
Anthony Townsend

CO M PA NY   R E G I S T R AT I O N   N U M B E R
3023689 (Registered in England)
The Company is an investment company as defined under
Section 833 of the Companies Act 2006
The Company was incorporated in England and Wales on
14 February 1995. The Company was incorporated as
Finsbury Worldwide Pharmaceutical Trust PLC.
W E B S I T E
Website: www.finsburywp.com
R E G I S T E R E D   O F F I C E
One Wood Street
London EC2V 7WS
I N V E S T M E N T   MA N AG E R
OrbiMed Capital LLC
767 Third Avenue, 30th Floor
New York NY10017 - 2023
Website: www.orbimed.com
Registered under the U.S. Securities & Exchange Commission
MA N AG E R ,   A D M I N I S T R ATO R   A N D   CO M PA NY
S E C R E TA RY
Frostrow Capital LLP
25 Southampton Buildings, London WC2A 1AL
Telephone: 0203 008 4910
E-mail: info@frostrow.com
Website: www.frostrow.com
Authorised and regulated by the Financial Services Authority
If you have an enquiry about the Company or if you would like to
receive a copy of the Company’s monthly fact sheet by e-mail,
please contact Frostrow Capital using the above e-mail address.
C U S TO D I A N
Goldman Sachs & Co.
200 West Street, Third Floor
New York, NY10282
AU D I TO R S
Ernst & Young LLP
1 More London Place
London SE1 2AF

63

R E G I S T R A R S
Capita Registrars
Northern House, Woodsome Park
Fenay Bridge, Huddersfield
West Yorkshire HD8 0GA
Telephone (in UK): 0871 664 0300†
Telephone (from overseas): + 44 208 639 3399
Facsimile: + 44 (0) 1484 600911
E-mail: ssd@capitaregistrars.com
Website: www.capitaregistrars.com

R E G I S T R A R S   (CO N T I N U E D)
Please contact the Registrars if you have a query about a 
certificated holding in the Company’s shares.
calls cost 10p per minute plus network charges and may be recorded for
training purposes. Lines are open from 8.30 a.m. to 5.30 p.m. Monday to
Friday.

†

S TO C K B R O K E R
Winterflood Securities Limited
The Atrium Building
Cannon Bridge, 25 Dowgate Hill
London EC4R 2GA

A L L I A N C E  T R U S T   S AV I N G S   L I M I T E D
PO Box 164
8 West Marketgait
Dundee
DD1 9YP

Customer Services: 01382 573737*
E-mail: contact@alliancetrust.co.uk.
Please contact Alliance Trust Savings Limited if
you have a query concerning an Alliance Trust
Savings Scheme, First Steps Plan or ISA account.
Calls to this number are recorded for monitoring purposes only and will be
charged at local rates, non-BT line charges may vary.

*

S H A R E   A N D  WA R R A N T   P R I C E   L I S T I N G S
The price of your shares and warrants can be found in various
publications including the Financial Times, The Daily Telegraph,
The Times, The Scotsman and The Herald.

The Company’s net asset value per share is announced daily
and is available, together with the share price, on the TrustNet
website at www.trustnet.com.

I D E N T I F I C AT I O N   CO D E S
Shares:

Subscription Shares:

:
SEDOL
ISIN
:
BLOOMBERG :
:
EPIC
:
SEDOL
:
ISIN
BLOOMBERG :

0338530
GB0003385308
FWP LN
FWP
B3VMCB0
GB00B3VMCB07
FWPS LN

D I S A B I L I T Y   AC T
Copies of this annual report and other documents issued by the Company are available from the Company Secretary. If needed,
copies can be made available in a variety of formats, including Braille, audio tape or larger type as appropriate. You can contact
the Registrar to the Company, Capita Registrars, which has installed telephones to allow speech and hearing impaired people
who have their own telephone to contact them directly, without the need for an intermediate operator, for this service please call
0800 731 1888. Specially trained operators are available during normal business hours to answer queries via this service.
Alternatively, if you prefer to go through a ‘typetalk’ operator (provided by the RNID) you should dial 18001 followed by the
number you wish to dial.

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This report is printed on Revive 75 Silk. The paper consists of 50% de-inked post consumer waste, 25% pre-consumer waste and 25% virgin wood

fibre. The pulp used is a combination of Elemental Chlorine Free (ECF) and Totally Chlorine Free (TCF). The mill is certified to environmental

management standard ISO 14001. This product has been awarded the NAPM 75% Recycled Mark. This report has been printed using vegetable

based inks.

Perivan Financial Print 217687

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Finsbury Worldwide Pharmaceutical Trust PLC
25 Southampton Buildings, London  WC2A 1AL
www.finsburywp.com

2010

F I N S B U RY  W O R L D W I D E  
P H A R MAC E U T I C A L  T R U S T   P LC

A N N UA L   R E P O R T &   F I N A N C I A L   S TAT E M E N TS
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