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BioNTech SE

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FY2023 Annual Report · BioNTech SE
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23

A C T I N G   T O G E T H E R

2

1

MAGAZINE

05

41

48

05

11

14

18

25

30

41

48

60

EXPLORING 
THE POWER OF 
COMBINATION

OUR PIPELINE

FACTS AND  
FIGURES

LETTER  
FROM  THE  
MANAGEMENT  
BOARD

INTERVIEW WITH 
HELMUT JEGGLE 
AND UGUR SAHIN

REPORT OF THE  
SUPERVISORY  
BOARD 

FROM FOUNDING  
VISION TO  
GLOBAL IMPACT

2023 HIGHLIGHTS

FINANCIAL  
CALENDAR,  
IMPRINT

BioNTech | Annual Report 20233

2

3

4

5

INDEPENDENT  
AUDITOR‘S REPORT
CONSOLIDATED  
FINANCIAL  
STATEMENTS

INDEPENDENT  
AUDITOR‘S REPORT
REMUNERATION  
REPORT

62

115

217

249

COMBINED MANAGEMENT  
REPORT 2023

GROUP REPORT 2023

COMPENSATION REPORT 
2023

FURTHER INFORMATION

FINANCIAL REPORT

BioNTech | Annual Report 2023Bispecific antibodies are protein molecules that can bind 
two different targets, bringing closer for example the 
cancer cell to the immune cell. When in close proximity 
of the cancer cell, the immune cell could recognize and 
orchestrate its elimination. 

4

1MAGAZINE

BioNTech | Annual Report 2023EXPLORING THE 
POWER OF  
COMBINATION

55

Our vision for future precision cancer treatments: 
We are developing a unique therapy toolbox  
designed to act together and with the aim to  
improve outcomes for patients.

BioNTech | Annual Report 20236

1

THE CHALLENGE // 
When a physician discusses a potential  
treatment plan with a patient who has just 
been diagnosed with cancer, they know that 
they will have to treat a disease with many 
different facets. Cancer cells are physically 
different from healthy cells in the body. Their 
shapes and properties are mutated and 
changed. They interact differently with their 
environment to grow abnormally and survive. 
And in each growing cycle, they have the 
potential to change further. The cells in the 
same tumor within the same patient can also 
be different. Medicine faces the challenge 
that every tumor is unique.

2

THE CONSEQUENCE // 
As a consequence, a standard of care might 
work for one, but not another patient. In 
other cases, the constant changes of the 
tumor cells lead to a resistance to available 
treatments. What may have originally given 
good results and helped the patient might not 
work over time. For example, it is estimated 
that more than 90%  of mortalities  in cancer 
patients can be attributed to chemotherapy 
resistance. 

Helping patients and addressing unmet  
medical needs is what drives us at BioNTech 
every day. We have been spending years on 
better understanding tumors’ differences as 
well as the immune system’s mechanisms to 
develop potential cancer treatments. We  
believe that the limitations cannot be over-
come by a single technology, but rather a 
therapy toolbox. 

DNA MUTATION

DNA MUTATION

SHARED  
TUMOR 
TARGET  
TPTE

CLDN6

PD-L1

HER-2

EPCAM

PATIENT- 
INDIVIDUAL
TUMOR  
TARGET

BioNTech | Annual Report 20237

SELECTED TARGETS

HER-2

CLDN6

Targeted therapies //

Cell therapies are designed to equip certain immune 
cells of the patients physically with structures (recep-
tors), enabling them to recognize cancer cells and 
orchestrate their elimination.

Antibody-drug conjugates (ADCs)  are designed 
to targetedly deliver a chemotherapy to tumor cells. 
Unlike traditional chemotherapy, cancer treatments 
with ADCs are designed to minimize the impact on 
healthy cells. 

Y

G

R

E

N

Y

S

SYNERGETIC 
SPACE FOR  
CURATIVE  
APPROACHES

Y
G
R
E
N
Y
S

S

Y

N

E

R

G

Y

3

OUR APPROACH //
We work on potential treatment approaches 
that aim to precisely target the specific tumor 
features by employing a different mechanism 
to tackle each feature. Our approach is to 
combine therapies – some investigational  
and some approved – with the aim of achieving  
better results compared to the current  
standard of care. This is why we are developing  
a suite of technologies which we call our  
oncology toolbox.

mRNA vaccines//

Immuno-modulators //

mRNA vaccines are designed to teach the immune 
system about features on the surface of cancer cells 
(targets), supporting immune cells to recognize and 
destroy them.

Mono- and bispecific antibodies  are designed to 
modulate the activity of immune cells and in some 
cases cancer cells, enhancing the immune response 
against cancer cells.

SELECTED TARGETS

PD-L1

EpCAM

SELECTED TARGETS

SHARED 
TUMOR 
TARGET TPTE

PATIENT- INDIVIDUAL 
TUMOR  
TARGET

Simplified illustration

BioNTech | Annual Report 2023investigational  
cell therapy 

B NT2 11

8

We have been evaluating  
combinational therapies since 
2014. Here is a selection of a few 
currently running clinical trials: 

BNT211 //

The product candidate BNT211 combines a 
CAR-T cell therapy candidate with an mRNA 
vaccine candidate. For the CAR-T cell therapy 
candidate, patients’ certain immune cells are 
equipped with a receptor to recognize the 
target protein CLDN6 and precisely attack 
cancer cells. The mRNA vaccine candidate 
encodes for CLDN6 and is designed to 
stimulate these CAR-T cells’ persistence 
and functionality in the body, complementing 
the CAR-T cells in a synergistic manner. This 
approach is aimed at more efficient recogni-
tion and elimination of cancer cells. BNT211 is 
currently being evaluated in Phase 1/2 clinical 
trials in patients with germ cell tumors.

mRNA vaccine candidate

Claudin-6 (CLDN6) is a surface protein expressed 
on multiple solid tumors such as ovarian cancer, 
sarcoma,  testicular cancer, endometrial cancer  
and gastric cancer.

BioNTech | Annual Report 2023BioNTech | Annual Report 2023

individualized mRNA 
vaccine candidate 

9

B NT122  + C H EC KPO I NT I N H I B ITO R

AUTOGENE CEVUMERAN/BNT1221   
+ CHECKPOINT INHIBITOR //

This potential treatment approach combines 
two different molecules to fight cancer. The 
individualized mRNA vaccine candidate 
BNT122 is designed to provide immune cells 
with information about the patient’s unique 
cancer cells and induce an immune response 
against the tumor. The checkpoint inhibitor 
is an antibody that keeps cancer cells from 
suppressing immune cells. This combinatory 
approach is intended to lead to a stronger and 
more specific immune response and elimina-
tion of cancer cells. BNT122 is currently being 
evaluated in Phase 2 clinical trials in patients 
with melanoma. 

checkpoint inhibitor

1) In collaboration with Genentech, a member of the Roche Group.

BioNTech | Annual Report 2023BioNTech | Annual Report 2023

10

checkpoint inhibitor

BNT311 + CHECKPOINT INHIBITOR

bispecific antibody  
candidate

ACASUNLIMAB/BNT3111 + CHECKPOINT 
INHIBITOR //

This investigational treatment approach  
consists of two antibodies and is intended to 
target cancer cells while enhancing immune 
cell functions in a potentially synergistic  
manner. BNT311 is a bispecific antibody that  
is designed to simultaneously address two 
targets at once: It binds to 4-1BB molecules, 
which are expressed on specific immune cells, 
with the aim of enhancing their function. It also 
binds to PD-L1 proteins, which are expressed 
on tumor cells, with the aim of preventing them 
from silencing immune cells. BNT311 is com-
bined with the current standard of care, which 
is a checkpoint inhibitor which also keeps 
cancer cells from suppressing immune cells. 
This combinational treatment approach is  
intended to increase the count of active 
immune cells that are able to recognize and 
eliminate cancer. BNT311 is currently being 
evaluated in Phase 2 clinical trials in patients 
with solid tumors, including non-small cell lung 
cancer and endometrial cancer.

1) In collaboration with Genmab.

BioNTech | Annual Report 202311

OUR  
PIPELINE

We are advancing a diversified portfolio of 
product candidates derived from our four drug 
classes focused on the potential treatment of 
cancer, infectious diseases and other serious 
diseases of unmet patient need.

BioNTech | Annual Report 2023ONCOLOGY // 

DRUG CLASS PLATFORM

PRODUCT  
CANDIDATE

BNT111 

BNT113

INDICATION (TARGET)

 PHASE 1

PHASE 1/2

 PHASE 2

PHASE 3

RIGHTS1

COLLABORATOR/
PARTNER

Advanced, R/R melanoma

Metastatic/R/R HPV16+ head and neck cancer

1L metastatic metastatic non-small cell lung cancer 

FixVac

BNT116

Advanced/metastatic non-small cell lung cancer

Fully owned2

12

iNeST

RiboMabs

1L advanced melanoma

Adjuvant colorectal cancer

Adjuvant pancreatic ductal adenocarcinoma

Multiple solid tumors

Multiple solid tumors (CD3×CLDN6)

Multiple solid tumors (IL-2 variant)

BNT122
(autogene
cevumeran) 

BNT142 

BNT151

mRNA

RiboCytokines

BNT152 + BNT153

Multiple solid tumors (IL-7, IL-2)

CELL  
THERA-
PIES

CAR-T cells + CARVac

BNT211

Multiple solid tumors (CLDN6)

Neoantigen-based T cells

BNT221

Refractory metastatic melanoma

BNT311/GEN1046
(acasunlimab)

aPD(L)1-R/R metastatic NSCLC (PD-L1×4-1BB)

Multiple solid tumors (PD-L1×4-1BB)

BNT312/GEN1042

Multiple solid tumors (CD40×4-1BB)4

BNT313/GEN1053

Multiple solid tumors (CD27)

BNT314/GEN1059

Multiple solid tumors (EpCAM×4-1BB)

BNT322/GEN1056

Multiple solid tumors 

aPD(L)1-R/R metastatic NSCLC (CTLA-4)

Platinum-resistant ovarian cancer (CTLA-4) 

Next-generation immune 
checkpoint modulators 

BNT316/ONC-392 
(gotistobart)

Metastatic castration-resistant prostate cancer (CTLA-4)

Multiple solid tumors (CTLA-4)

Targeted cancer antibodies

BNT321

Pancreatic cancer (sLea)

Multiple solid tumors (HER2)

BNT323/DB-1303

2L+, HR+/HER2-low metastatic breast cancer (HER2)

PROTEIN- 
BASED 
THERA- 
PEUTICS

Antibody-drug 
conjugates

BNT324/DB-1311

Multiple solid tumors (B7H3)

BNT325/DB-1305

Multiple solid tumors (TROP2)

BNT326/YL202

Multiple solid tumors (HER3)

SMI5

Toll-like receptor binding

BNT411

Multiple solid tumors (TLR7)

Collaboration Genentech3

Fully owned

Fully owned

Fully owned

Fully owned

Collaboration Genmab

Collaboration OncoC4

Fully owned

Collaboration Duality Biologics

MediLink  
Therapeutics

Collaboration

Fully owned

As of: March 20, 2024
1) For further details about BioNTech’s rights see quarterly reports under https://investors.biontech.de/financials-filings/quarterly-reports. 2) FixVac platform is fully owned by BioNTech. The BNT111 and BNT116 Phase 2 trials are jointly conducted with Regeneron as part of a cost-sharing 
strategic collaboration.  3) A member of the Roche Group.    4) Two Phase 1/2 clinical trials in patients with solid tumors are ongoing in combination with ICI+/- chemotherapy.  5) Small molecule immunomodulators.

BioNTech | Annual Report 2023 
 
 
INFECTIOUS DISEASES //

DRUG CLASS

PRODUCT CANDIDATE

INDICATION

  PHASE 1

PHASE 1/2

PHASE 2

PHASE 3

COMMERCIAL

RIGHTS1

COLLABORATOR/ PARTNER

13

BNT162b2

BNT162b2+BNT162b4
(T-cell enhancing)

BNT162b5/6/7 
(stabilized spike antigen) 

COVID-19

BNT162b2+BNT1616

COVID-19 – Influenza combination

BNT161

BNT163

BNT164

BNT165

BNT166

BNT167

mRNA

Influenza

Herpes simplex virus

Tuberculosis8

Malaria9

Mpox

Shingles

Collaboration

Collaboration

Collaboration

Pfizer
Fosun Pharma

Pfizer

Pfizer

Collaboration7

University of Pennsylvania

Funded by Bill & Melinda Gates 
Foundation

Fully owned

Fully owned

Fully owned

Funded by CEPI10

Collaboration

Pfizer

As of: March 20, 2024
1) For further details about BioNTech’s rights see quarterly reports under https://investors.biontech.de/financials-filings/quarterly-reports.  6) The COVID-19-Influenza combination is a Phase 3 trial in partnership with Pfizer. Further development is subject to entering into a definitive agreement. 
7) Out-licensed to Pfizer 8) Two Phase 1 clinical trials are ongoing (NCT05537038, Germany and NCT05547464, Republic of South Africa).  9) A Phase 1 clinical trial (NCT05581641) and a Phase 1/2 clinical trial (NCT06069544) are ongoing.  10) Coalition for Epidemic Preparedness Innovations (CEPI).

BioNTech | Annual Report 2023 
14

FACTS AND  
FIGURES

BioNTech | Annual Report 202315

OUR DIVERSE  
COMPANY
~ 6,300  

EMPLOYEES

> 2,500 

OF WHICH ARE IN RESEARCH & DEVELOPMENT

> 80 

NATIONALITIES FROM  
A LIKE AFGHANISTAN TO Z LIKE ZAMBIA

~ 51% 

FEMALE EMPLOYEES  
IN THE TOTAL WORKFORCE

All figures according to BioNTech’s annual report on Form 20-F for the year ended December 31, 2023 
available on https://investors.biontech.de/node/15956/html; accessed March 22, 2024.

BioNTech | Annual Report 202316

OUR INNOVATIVE  
PIPELINE

ONCOLOGY

INFECTIOUS DISEASES

PHASE 1 TRIALS

PHASE 1 TRIALS

PHASE 2 TRIALS

PHASE 2 TRIALS

PHASE 3 TRIALS

PHASE 3 TRIALS

6

19

1

13

2

2

8

20

1

1

5

1

1

9

2021

2022

2023

Sources: 2023: 20-F;  2022: 20-F, Link: https://investors.biontech.de/node/14881/html;  2021: 20-F, Link: https://investors.biontech.de/node/9571/html;  Phase 1 also includes Phase 1/2 trials.

BioNTech | Annual Report 2023OUR GLOBAL  
FOOTPRINT1

LOCATIONS GLOBALLY // 

17

MAINZ (HEADQUARTERS)

HALLE

BERLIN

LOCATIONS  
IN GERMANY //

IDAR-OBERSTEIN

MARBURG

MARTINSRIED

NEURIED

CAMBRIDGE (UK) 

LONDON (UK)

VIENNA (AUSTRIA)

ISTANBUL (TÜRKIYE)

SAN FRANCISCO (USA)

GAITHERSBURG (USA)

CAMBRIDGE (USA)

PARIS (FRANCE)

SHANGHAI (CHINA)

SINGAPORE

LAGOS  
(NIGERIA)

TUNIS (TUNISIA)

KIGALI (RWANDA)

MELBOURNE (AUSTRALIA)

BioNTech locations

InstaDeep locations

CAPE TOWN (SOUTH AFRICA)

BioNTech  & InstaDeep locations

1) As of March 20, 2024.

BioNTech | Annual Report 202318

LETTER  
FROM THE  
MANAGEMENT  
BOARD

SEAN MARETT
CHIEF BUSINESS  
OFFICER AND CHIEF  
COMMERCIAL OFFICER

RYAN RICHARDSON
CHIEF STRATEGY OFFICER

JAMES RYAN, PH.D. 
CHIEF LEGAL OFFICER

JENS HOLSTEIN
CHIEF FINANCIAL  
OFFICER

SIERK POETTING, PH.D.
CHIEF OPERATING  
OFFICER

PROF.  
ÖZLEM TÜRECI, M.D.
CHIEF MEDICAL OFFICER

PROF. UGUR SAHIN,M.D.
CHIEF EXECUTIVE  
OFFICER

BioNTech | Annual Report 202319

DEAR  
SHAREHOLDERS,

“Acting together” – the title of this 
year’s annual report – reflects our 
commitment to developing thera-
pies with combination or synergistic 
potential with the aim of revolution-
izing the field of medicine. 

2023 was a year in which we made good 
progress on many fronts: maintaining our 
position in the COVID-19 vaccine market,  
advancing our oncology pipeline, and 
strengthening our organization in preparation of 
the next growth phase, including our planned 
product launches in oncology. We presented 
encouraging data from our oncology pipeline 
and now have an increasing number of mid- 
and later-stage clinical trials. 

We believe that we have the financial ability to 
fund a diversified pipeline and to strengthen 
our core capabilities with external innovation. 
At the same time, we continue our efforts to 
support developing a global ecosystem to 
bring innovative therapies to patients where 
they are needed. Thus, we believe that we 
have the technology, the capabilities, and the 
team to work towards a new era of precision 
medicine. 

OUR COVID-19 VACCINE FRANCHISE //
Last year, we demonstrated that we have 
successfully built a leading COVID-19 vaccine 
franchise in collaboration with our partner 
Pfizer Inc. (“Pfizer”), both commercially and 
scientifically. 

This was underlined by our leading market 
position in the United States, the European 
Union (“EU”), and Japan.1 Since 2021, we 
have shipped more than 4.5 billion doses of 
COVID-19 vaccines to over 180 countries 
and territories. 2 In 2023 alone, we distributed 
over 460 million total vaccine doses, of which 
over 190 million doses were our successfully 
launched Omicron XBB.1.5-adapted monova-
lent COVID-19 vaccine.3

As we transitioned out of the pandemic into 
a more endemic-like situation, 2023 helped 
us better understand the future demand for 
COVID-19 vaccines. We expect COVID-19 
to remain an annual seasonal disease with 
peaks in the respiratory infection season: This 
means that vaccinations are likely to largely shift 
to annual seasonal use, and we are adapting 
our company accordingly. 

The transition of SARS-CoV-2 to an endemic 
infectious disease had an effect on our 2023 
revenues, which were at approximately 
€3.8 billion. In the same period, we had less 
expenditures than originally planned, and 
we maintained a strong financial position. 

1) Company assessment as of December 3, 2023. 2) Partnered with Pfizer; cumulative doses shipped in the years 2021-2023. 3) Figures according 
to BioNTech’s annual report on Form 20-F for the year ended December 31, 2023, available at https://investors.biontech.de/node/15956/html; 
accessed March 22, 2024. 

BioNTech | Annual Report 202320

with approximately €17.7 billion in cash, cash 
equivalents, and security investments. We 
remained profitable in 2023, ending the year 
with approximately €0.9 billion in net profit. 
As we look to 2024, we expect our COVID-19 
vaccine franchise to stay cash-generative 
given our partnership model with Pfizer. We 
will continue to focus on cost discipline, even 
as we invest in the next wave of innovation. 

The World Health Organization (“WHO”) 
expects that SARS-CoV-2 will remain a risk 
for people around the world as new variants 
emerge, making the need for addressing it 
critical.4 In line with our goal to provide people 
worldwide with COVID-19 vaccines that are 
adapted to newly circulating virus variants 
or sublineages, we launched an Omicron 
XBB.1.5-adapted monovalent COVID-19  
vaccine. We have introduced single-dose 
vials and non-frozen pre-filled syringes in 
the United States, which we delivered in line 
with the orders. We expect a transition from 
advanced purchase agreements to commercial 
market ordering in more geographies in the 
future.  

Looking ahead, it is our goal to continue 
building a sustainable respiratory vaccine 
business and retain a market-leading position 
in COVID-19 vaccines. To this end, we have 
continued to work on combination vaccine 
candidates with Pfizer. Our combination  
vaccine candidate against COVID-19 and  

4)  https://www.who.int/europe/news/item/12-06-2023-with-the-inter-
national-public-health-emergency-ending--who-europe-launches-its-
transition-plan-for-covid-19, accessed February 15, 2024

BioNTech | Annual Report 2023 
We believe combining  
complementary treatment  
modalities may enable us to  
better leverage the potential  
of each technology to provide 
precise and personalized  
treatments to patients,  
improving outcomes and  
reducing the risk of resistance  
to therapies.

21

influenza moved into a Phase 3 trial in  
December 2023. 

A GROWING MID- AND LATE-STAGE 
ONCOLOGY PIPELINE //
In 2023, we successfully advanced and 
broadened our diversified pipeline and now 
have multiple ongoing registrational trials.  
We also have leveraged our strong financial  
position with continued investment in R&D. 

Our oncology pipeline is set to drive long-
term growth for the company. It is based on 
our understanding that cancer is a highly  
individual disease. To this end, we want to 
lead in the individualization of cancer med-
icine and address the continuum of cancer 
treatments and bring novel therapies to  
patients, from early disease stages to late-
stage metastatic disease. 

We have built a portfolio of different platform 
technologies with combination potential and 
synergistic mechanisms of action, encom-
passing development programs for immuno-
modulators, cell and precision therapies, as 
well as personalized mRNA vaccines across 
a wide range of solid tumors and stages of 
treatment. With this approach, we aim for a 
widespread application of our platform tech-
nologies in combination with effective target 
selection to address a range of solid tumors 
in different stages of the disease with high 
medical need.

In 2023, we not only complemented the  
pipeline with in-licensed assets, but also  
presented encouraging data at various  
scientific conferences across our platform 
technologies. This included data for the 
investigational mRNA vaccine program  
autogene cevumeran/BNT1225 in patients with 
adjuvant pancreatic ductal adenocarcinoma,  
our fully owned autologous cell therapy 
candidate BNT211 in combination with an 
mRNA booster, and data on programs we are 
developing with partners. The data present-
ed for the antibody candidate BNT3166 for 
patients with non-small cell lung cancer and 
the investigational antibody drug conjugate 
BNT3237 for endometrium and breast cancer 
patients led to the start of pivotal Phase 3 
trials for both assets.

We believe combining complementary 
treatment modalities may enable us to better 
leverage the potential of each technology to 
provide precise and personalized treatments 
to patients, improving outcomes and reducing 
the risk of resistance to therapies. We expect 
to continue building and maturing our oncology 
pipeline in 2024 in anticipation of potential 
commercial oncology launches as soon as 
2026, if approved. We aim to have ten or more 
indication approvals by 2030. 

5) I In collaboration with Genentech Inc. (“Genentech”), a member of the Roche Group. 6)  In collaboration with OncoC4, Inc. (“OncoC4”).  
7)  In collaboration with Duality Biologics (Suzhou) Co. Ltd. (“DualityBio”).

BioNTech | Annual Report 202322

BioNTech | Annual Report 202323

ECOSYSTEM DEVELOPMENT //
Our vision is to improve the health of people 
worldwide by bringing innovative therapies 
to patients where they are needed. To this 
end, we initiated a number of public-private 
partnerships in 2023, which aim to support 
the development of immunotherapies and 
vaccines as well as expand access to our 
product candidates, building on our expertise 
in R&D as well as manufacturing.

We entered into a collaboration with the  
government of the United Kingdom to  
augment our clinical trial network for person-
alized mRNA immunotherapies with the aim to 
provide personalized cancer therapies for up 
to 10,000 patients by the end of 2030, either 
in clinical trials or as authorized treatments. In 
the state of Victoria in Australia, we entered a 
multi-year partnership aimed at strengthen-
ing the local mRNA ecosystem by supporting 
the development of innovative medicines 
from research to application in the clinic. We 
intend to progress the development of inves-
tigational mRNA-based medicines and other 
product candidates with the aim of treating 
up to 4,000 cancer patients in Australia and 
New Zealand over a ten-year period, either in 
clinical trials or as authorized treatments. 

initiatives to help build a sustainable and resil-
ient African vaccine ecosystem. Our state-
of-the-art manufacturing site in Kigali could 
become the first commercial-scale mRNA 
manufacturing facility on the continent, and 
we plan to equip it to manufacture a range of 
mRNA-based vaccines targeted to the needs 
of the African Union member states. 

This ties in with our development activities 
for prophylactic mRNA vaccine candidates 
targeting infectious diseases such as tuber-
culosis, malaria, and HIV, as well as dis- 
eases with epidemic and pandemic potential, 
including mpox. Clinical trials for tuberculosis 
and malaria vaccine programs are already 
underway in South Africa and the United 
States, respectively. By the end of 2024, we 
plan to have ongoing clinical trials in Africa for 
vaccine candidates against malaria, tubercu-
losis, and HIV.

STRENGTHEN CORE CAPABILITIES 
WITH EXTERNAL INNOVATION //
We have made significant progress in  
enhancing our core capabilities with external 
innovation. The rationale behind these deals 
is to strengthen our backbone and comple-
mentary technologies, and we have already 
started to create value. 

2023 also marked an important milestone in 
our efforts to help support equitable access 
to novel medicines globally: We inaugurated 
our site in Kigali, Rwanda, which is one of our 

In 2023, we entered into licensing deals for 
six different clinical stage assets, including 
in-licensing an investigational antibody  

candidate from each of OncoC4 and Biotheus 
Inc. (“Biotheus”), as well as investigational 
antibody-drug conjugates from DualityBio 
and MediLink Therapeutics (Suzhou) Co., Ltd. 
(“MediLink”). Two of those assets – BNT316 
and BNT323 – moved into pivotal trials within 
six months of signing the respective deal. 

We also acquired InstaDeep Ltd.  
(“InstaDeep”) with the intent to integrate 
world-class capabilities in supercomputing, 
artificial intelligence (“AI”) research, and 
generative AI into drug design and delivery. 
Examples include optimization of mRNA and 
protein design, and end-to-end optimization 
for personalized medicines from genome 
and mutanome analysis to target prediction 
and manufacturing. We aim to implement AI 
and machine learning capabilities into our 
processes even more, planning to scale our 
platforms so that we are able to develop 
more precise products and provide them to 
patients more efficiently.

We will continue to focus on scaling the busi-
ness for commercial readiness in oncology 
in multiple countries by the end of 2025. One 
step toward achieving this is our strategic 
collaboration with Autolus Therapeutics plc 
(“Autolus”), which we signed in February 
2024. The collaboration grants us the option 
to access Autolus’ commercial and clinical 
site network, CAR-T cell therapy manufac-
turing capacities, and commercial supply 

BioNTech | Annual Report 202324

Your Management Board, 

Prof. Ugur Sahin, M.D.
Chief Executive Officer

Jens Holstein
Chief Financial Officer

Sean Marett
Chief Commercial Officer, 
Chief Business Officer

Sierk Poetting, Ph.D.
Chief Operating Officer

Prof. Özlem Türeci, M.D.
Chief Medical Officer

Ryan Richardson
Chief Strategy Officer

James Ryan, Ph.D.
Chief Legal Officer 

infrastructure in a cost-efficient set-up. This 
has the potential to enable the expansion of 
our cell therapy program BNT211 into trials for 
multiple cancer indications. 

A NOTE ON ACTING TOGETHER //
“Acting together” is not only a description of 
our pipeline approach, but also a reflection of 
our culture. At BioNTech, we believe in acting 
together not only within the company, but also 
with stakeholders, including our collabora-
tors, business partners, regulators, communi-
ty members, and many more. We saw during 
the COVID-19 pandemic that this approach 
was instrumental in successfully reaching 
a common goal, and we are convinced that 
by acting together, we will be able to work 
towards our vision of improving the health of 
people worldwide.

The development of the COVID-19 vaccine 
has transformed BioNTech. The realization of 
our oncology pipeline has the same potential 
to transform our company once more. Howev-
er, this will only be possible thanks to the con-
tinued unrelenting commitment, passion, and 
hard work of our employees. We would also 
like to thank you, our shareholders, for your 
continued support and look forward to taking 
the next steps to turn our vision into reality. 

“Acting together” 
is not only a description 
of our pipeline approach, 
but also a reflection 
of our culture.

BioNTech | Annual Report 202325

INTERVIEW WITH 
HELMUT JEGGLE 
AND UGUR SAHIN

BioNTech | Annual Report 2023BioNTech | Annual Report 2023

26

“The COVID-19 vaccine  
has not only contributed  
significantly to BioNTech’s  
revenues but has also shown  
the efficiency of a business  
model which is based on  
innovative technologies.”

HELMUT JEGGLE
CHAIRMAN  OF THE  
SUPERVISORY BOARD

How would you summarize the  
year 2023?

What goals did you set for yourself in 2023, 
and did you achieve them?

HELMUT JEGGLE // While the years 2020 
to 2022 were characterized by the develop-
ment, large-scale production and supply of 
the COVID-19 vaccine together with Pfizer, 
2023 was a year in which BioNTech refo-
cused to advance a core area: our oncology 
pipeline. The Company tailored its strategy by 
in-licensing further product candidates in late-
stage clinical development. These included 
antibody-drug conjugates, or ADCs, a new 
targeted form of chemotherapy. BioNTech’s 
goal is to be as efficient as possible in submit-
ting these candidates for regulatory approval.

UGUR SAHIN // We believe antibody-drug 
conjugates represent an exciting and import-
ant advancement in medicine, and we expect 
their broad applicability in the treatment of 
cancer within the next 15 years. We have 
forged collaborations with powerful and 
innovative partners in this field with whom we 
are jointly developing these candidates. We 
envision an exciting opportunity to combine 
ADCs with our proprietary product candi-
dates, which also aligns with our strategy of 
developing complementary and synergistic 
therapeutic approaches. By doing so, we 
aim to extend the reach of our therapies to 
broader patient populations, thereby making 
a tangible difference in their lives.

UGUR SAHIN // We had three overarching 
goals in 2023, all of which were successfully 
achieved at BioNTech. Our first goal was to 
close the financial year on a profitable note 
while maintaining our leadership in COVID-19 
vaccines. This objective was met, largely 
due to our effective development and rollout 
of a variant-adapted vaccine. Second, we 
sought to strategically invest in our oncology 
pipeline, launching several potentially pivotal 
trials in 2023 while bolstering our technology 
platforms through strategic collaborations to 
further solidify our position in this area. Third, 
within the realm of infectious diseases, we 
successfully advanced our vaccine candi-
dates targeting shingles, tuberculosis and 
mpox into clinical trials. We anticipate initial 
data for some of these candidates in 2024.

How significant is the COVID-19 vaccine 
business for BioNTech? Are there additional 
revenue streams for the Company?

UGUR SAHIN // The COVID-19 vaccine,  
including its seasonal adapted variant vac-
cines, are our only approved product to date. 
In 2023, we witnessed a pivotal transition 
from the pandemic phase to more and more 
seasonal vaccination campaigns. In many 
countries, a vaccination against COVID-19 

BioNTech | Annual Report 202327

is now recommended primarily for older 
individuals and those with underlying health 
conditions, leading to a corresponding decline 
in demand for the COVID-19 vaccine. Looking 
ahead, we anticipate an ongoing need for 
seasonal, variant-specific vaccines tailored to 
specific population groups. It’s imperative for 
us to address this seasonal dynamic while si-
multaneously advancing the development of a 
combination vaccine targeting both COVID-19 
and influenza. In addition to our COVID-19 vac-
cine business, we generate revenues through 
our service-based enterprises, including sub-
sidiaries like InstaDeep, JPT Peptide Technol-
ogies, and IMFS, as well as revenues from our 
pandemic preparedness contract in Germany. 

GROBENTWURF

HELMUT JEGGLE // The COVID-19 vaccine 
has not only contributed significantly to BioN-
Tech’s revenues but has also shown the effi-
ciency of a business model which is based on 
innovative technologies. From the initial stages 
of research and development to the estab-
lishment of robust production capacities and 
logistics infrastructure to meet the demand, 
BioNTech’s comprehensive vertical integration 
exceeded the expectations set at the time of 
its IPO. This revenue stream is also serving as 
a valuable lesson in cost discipline, providing 
BioNTech with a defined financial framework 
to pursue other innovative projects. With this 
foundation in place, the Company now has the 
opportunity to solidify its business model and 
extend its success into oncology.

What expenditures do you expect in 2024, 
and where will you allocate investments in 
particular?

UGUR SAHIN // Our focus is specifically 
on three core areas: advancing potentially 
registrational trials with the aim of product 
launches in oncology, ensuring the Company’s 
organizational launch readiness, and the 
ongoing development of our pipeline en-
compassing vaccine candidates targeting 
COVID-19 and other infectious diseases.
The bulk of our expenditure is allocated to  
oncology, primarily to support more advanced- 
stage clinical trials and the launch readiness. 
Furthermore, we are advancing several 
vaccine candidates for infectious diseases 
into the next clinical phase. In addition, in 
2023, we have further bolstered our interna-
tional presence to facilitate clinical trials and 
prepare for potential market launches across 
various regions, including the US, the UK, 
Singapore, Rwanda, and Australia.

What are your goals for 2024 and the  
upcoming years in the field of oncology?

UGUR SAHIN // By the end of 2024, we aim 
to have a ten or more clinical trials with regis-
trational potential across various indications 
within our pipeline. Our overarching target in 
oncology is to launch the first product, if ap-
proved, by 2026 and to secure ten indication 
approvals by 2030. Our vision is to transform 

BioNTech into a sustainable income-gen-
erating entity through a series of approvals, 
thereby delivering tangible value to patients, 
the society, investors, and the Company alike.

HELMUT JEGGLE // What Ugur Sahin is  
setting out here are very ambitious goals 
indeed. It is therefore important that the 
Company strikes a balance between R&D and 
commercialization. BioNTech had already 
started to build an organization to successfully 
commercialize its oncology products. This 
remains an important strategic aspect in 2024.

You have licensed new candidates.  
What is the rationale behind this?

UGUR SAHIN // The candidates we have 
in-licensed hold significant strategic impor-
tance for us because we believe they possess 
the potential to be used in patients to achieve 
a potent effect in advanced disease settings 
and could have synergies with our immu-
notherapies. For instance, ADCs offer the 
possibility to debulk large tumors to eradicate 
residual tumor cells through subsequent 
immunotherapy. Currently, we are assessing 
ADCs targeting specific types of cancer in 
the lung, breast, and gastrointestinal tract. In 
combination with ADCs, we expect to be able 
to extend the scope of our immunotherapies 
to advanced cancers.

BioNTech | Annual Report 2023“Cancer is not a single disease, 
but rather a spectrum of  
diseases, each unique in its 
characteristics. Hence, our 
pipeline is structured into  
three distinct therapeutic  
approaches.”

PROF. UGUR SAHIN, M.D.
CHIEF EXECUTIVE OFFICER

28

HELMUT JEGGLE // At an early stage, 
BioNTech recognized the opportunity and 
combined a scientific pioneering spirit with 
strong entrepreneurship in the ADC space. 
It is noteworthy that two of the in-licensed 
product candidates, one an antibody can-
didate and the other an ADC candidate, are 
already being evaluated in Phase 3 studies.

Mr. Jeggle, in the 2021 annual report you 
said that BioNTech is fully financed until the 
next product launch. Do you stand by that 
statement? Will the Company propose a 
dividend to shareholders this year? 

HELMUT JEGGLE // Given the Company’s 
ambitious targets, there is currently little  
latitude for dividends, which will not be 
proposed at the upcoming Annual General 
Meeting. BioNTech’s primary objective is to 
develop the Company into sustainable  
profitability by 2030 without the need for 
additional capital. The potential for future divi-
dends is also contingent upon sales from our  
COVID-19 vaccine business. Hence, in 2023, 
we established a Product Committee at  
BioNTech to further develop the product 
pipeline with a target-oriented approach, 
paving the way for market access.

The feedback we have received by both 
private and institutional investors is that they 
recognize the Company’s potential, grounded 
in its scientific standing, and endorse the 

BioNTech | Annual Report 202329

You have a well-filled pipeline with over 30 
candidates in oncology alone and across 
different drug classes. How is that made 
up? Why do you need so many candidates?

of approval.  Our strategic intent is to position 
ourselves to commercialize these products 
across various indications in the future, thereby 
expanding their reach and impact.

strategy of leveraging BioNTech’s financial 
position to spearhead the next wave of  
potential product launches.

What was BioNTech’s strategic direction 
when it went public, and has the Company 
maintained that course?

UGUR SAHIN // Our objective was to pioneer 
the next generation of immunotherapies, aiming 
to significantly enhance treatment outcomes 
for cancer patients. Our focus was and still is to 
help shape a new era of personalized medi-
cine as pioneers. In 2023, we found ourselves 
poised to realign with our original mission. The 
notable difference from 2019 lies in our new-
found financial and organizational resources 
that empower us to turn our vision into reality 
on a grander scale. This achievement is based 
on the dedication and ambition of our teams, 
whose passion has propelled us forward. We 
extend our gratitude to our colleagues who 
work diligently with us every day to actively 
shape the medicine of tomorrow.  

UGUR SAHIN // Cancer is not a single disease, 
but rather a spectrum of diseases, each unique 
in its characteristics. Hence, our pipeline is 
structured into three distinct therapeutic 
approaches. First, we are dedicated to devel-
oping candidates for targeted therapies, which 
encompass modalities such as CAR-T cell 
therapies or ADCs. These interventions are 
primarily tailored to combat cancer in patients 
at advanced stages of the disease. Second, our 
focus extends to the development of immuno-
therapies, exemplified by antibodies, aimed at 
fortifying the immune system. This holds the 
potential to exert long-term control over tumors 
in some patient populations. The third compo-
nent of our pipeline centers  
on personalized mRNA cancer vaccine  
candidates designed to prevent relapses  
and metastases effectively.

HELMUT JEGGLE // From my perspective, 
two key factors stand out: First, BioNTech now 
has the autonomy to self-finance, based on its 
COVID-19 vaccine business. Consequently, 
influence of external risks has been reduced. 
Second, the Company has experienced a  
remarkable surge in both growth and exper-
tise – arguably surpassing what was foresee-
able back in 2019.

We pride ourselves on being among the few 
companies committed to researching a diversi-
fied toolbox comprising of various mechanisms 
of action, including the aspect of whether and 
how these could be combined and act syner-
gistically to enhance their effect. We are initially 
evaluating the therapeutic approaches in indi-
cations with a high medical need or for larger 
patient populations for which we see probability 

What are you looking forward to in 2024?

HELMUT JEGGLE // It is an important year for 
BioNTech. The year 2024 marks a new begin-
ning, and that always means something exciting. 
This year, our focus is on fortifying our organi-
zational infrastructure for commercialization in 
furtherance of launch readiness, 
and on enhancing transparency in product de- 
velopment progress, particularly in potentially 
registrational trials. BioNTech has consistently 
demonstrated its strength as a cohesive team, 
and I want to extend my heartfelt appreciation 
for everyone’s passion, dedication,  
and drive. Without each individual’s contribu-
tion, the Company would not be where it stands 
today.

UGUR SAHIN // Thank you, Helmut, I share 
your sentiment wholeheartedly. As part of 
this remarkable team, I am eager to propel our 
candidates toward market launch, pending 
regulatory authorization, and demonstrate the 
value they bring to both the Company and to 
society. We have a unique opportunity to drive 
transformative change in the field of medicine, 
and I firmly believe we have everything it takes 
to establish BioNTech as one of the leading 
global immunotherapy companies.

BioNTech | Annual Report 202330

REPORT OF THE  
SUPERVISORY BOARD ON  
THE FINANCIAL YEAR 2023

PROF. RUDOLF  
STAUDIGL, PH.D.

PROF. ANJA  
MORAWIETZ, PH.D.

PROF. CHRISTOPH  
HUBER, M.D.1

HELMUT JEGGLE
CHAIRMAN  OF THE  
SUPERVISORY BOARD

NICOLA  
BLACKWOOD 1

MICHAEL  
MOTSCHMANN

ULRICH  
WANDSCHNEIDER, PH.D.

1) Nicola Blackwood was elected to the Supervisory Board on May 25, 2023. She succeeded  
Prof. Christoph Huber, M.D., who left the Supervisory Board after reaching the retirement age limit.

BioNTech | Annual Report 202331

In the past year, BioNTech SE continued to transition towards becoming a  
leading global immunotherapy Company. The Company maintained its leading  
position for COVID-19 vaccines in key markets. At the same time, BioNTech focused 
on its growing oncology pipeline and advanced several candidates from different 
drug classes to later stages of development. Part of this effort also included the 
Management Board’s strategic decision to license clinical projects in late-stage  
development to be able to further additional candidates towards regulatory  
submission and to potentially develop new oncology treatment standards in-house 
and combine them with other therapies.

BioNTech | Annual Report 202332

In addition, BioNTech strengthened its 
technology platforms, digital capabilities, 
and infrastructure through corresponding 
investments and strategic partnerships. This 
includes the acquisition of InstaDeep Ltd. 
(“InstaDeep”) as part of BioNTech’s strategy 
to build world-leading capabilities in AI- 
driven drug discovery and the development 
of next-generation immunotherapies and 
vaccines to address diseases with high  
unmet medical needs.

Combining all these factors with the Company’s 
strong financial position places BioNTech 
well for 2024. In the current financial year, 
the aim will be to deploy resources with the 
necessary level of cost discipline, while the 
Management Board will continue to focus on 
the oncology segment, and the Company is 
preparing to potentially launch its first oncology 
products in various markets.

Throughout the financial year 2023, the 
Supervisory Board, under my Chairmanship, 
performed its duties and obligations in  
accordance with the law and the Articles  
of Association, as well as its Rules of Proce-
dure. At the Annual General Meeting on May 
25, 2023, the Supervisory Board changed 
its composition: Prof. Christoph Huber, 
M.D. stepped down, and Baroness Nicola 
Blackwood was elected as a member of the 
Supervisory Board of BioNTech SE as his 
successor.  

Nicola Blackwood is Chairwoman of the  
Advisory Board of Oxford University Innovation 
Ltd., CEO of Blackwood Intelligence Ltd., 
Chairwoman of the Advisory Board of 
Genomics England as well as an indepen-
dent advisor. She complements the Board’s 
established competence profile particularly 
with her expertise in the areas of science 
and innovation, as well as her strong strate-
gic and analytical skills. Nicola Blackwood 
also has proven expertise in research and 
development, digitalization, and corporate 
social responsibility (CSR)/sustainability 
and international experience in the markets 
relevant to the Company. During the Annual 
General Meeting of the financial year 2023, 
Ulrich Wandschneider, Ph.D. and Michael 
Motschmann were re-elected, which con-
tributes to the continuity and a sustainable 
long-term focus of the Company.

CONTROL AND MONITORING  
FUNCTION OF THE SUPERVISORY 
BOARD TOWARDS THE  
MANAGEMENT BOARD//
The Supervisory Board continuously  
monitored the Management Board,  
regularly advised it, and oversaw the  
strategic development of the Company.

As the Supervisory Board, we closely follow 
the rapid development of the Company, and 
we apply our know-how, entrepreneurial  
focus, and approach of agile control to  

support BioNTech’s business activities and 
its team. Among other things, the Management 
Board regularly informed us about current 
business activities and future business 
planning (including financial, investment and 
personnel planning). In addition, we regularly 
consulted with the Management Board on 
the risk situation, risk management and 
compliance in the Company. As Chairman of 
the Supervisory Board, I was also in regular 
contact with the Management Board beyond 
the Supervisory Board meetings. Within this 
framework, I was routinely informed about all 
matters relating to the Company, including 
its legal and business relations with affiliated 
companies, and all significant business trans-
actions and matters at affiliated companies.

On the basis of reporting by the Management 
Board, which was prepared in cooperation 
with the respective specialist departments, 
we discussed business developments and 
events of importance to the Company in detail. 
Where necessary, the Supervisory Board was 
supported in this by the respective responsible 
committees. We, as the Supervisory Board, 
maintain an active dialogue with the Manage-
ment Board to embrace BioNTech’s rapid 
development and to review their decisions, 
considering the opportunities and risks  
without any unnecessary delays. In doing so, 
we always keep in mind the Company’s goals: 
for example, the goal of having several  
products that are market-ready by 2030.  

BioNTech | Annual Report 202333

The Supervisory Board was directly involved 
at an early stage in all decisions of fundamental 
importance to the Company. Where the law, 
the Articles of Association or the Rules of 
Procedure required the approval of the  
Supervisory Board for individual measures,  
a corresponding resolution was passed.  
The Supervisory Board approved the respec-
tive resolutions proposed by the Manage-
ment Board after thorough examination and  
discussion.

Cooperation with the Management Board of 
BioNTech was characterized by responsible 
and goal-oriented action in every respect. 
The Management Board fully fulfilled its  
reporting obligations to the Supervisory Board, 
both verbally and in writing, to constantly  
enable the Supervisory Board to assure itself 
as to the legality and regularity, appropriate-
ness, and economic efficiency of the man-
agement of the Company.

FOCUS TOPICS AND MEETINGS OF THE 
SUPERVISORY BOARD //
A total of six ordinary meetings were held 
in the financial year 2023, during which the 
strategic development of the Company was 
discussed, generally jointly with the Man-
agement Board. The 2023 meetings were 
held on March 08, March 23, May 10, May 25, 
September 14, and December 14, 2023. All 
members of the Supervisory Board attended 
the individual meetings except for the  

BioNTech | Annual Report 202334

meeting on March 23, which Prof. Rudolf 
Staudigl and I, Helmut Jeggle, were unable 
to attend. Members of the BioNTech Man-
agement Board also attended some of these 
meetings. All Management Board members 
attended the meetings on March 08, September 
 14, and December 14, 2023. In addition, Jens 
Holstein attended the meeting on March 23 
and all Management Board members except 
for Prof. Özlem Türeci, M.D. attended the 
meeting on May 10. The meeting on May 25 
was held without the Management Board. 
A short meeting was also held following the 
quarterly meeting on December 14, which 
was only attended by James Ryan, Ph.D. from 
the Management Board. A multi-day strategy 
workshop was held in March and September 
2023, respectively, and was attended by 
the entire Supervisory Board and Manage-
ment Board to discuss the Company’s future 
strategic direction. Within the framework of 
the meetings and outside the meetings, the 
Supervisory Board also met and discussed 
regularly without the Management Board. All 
six ordinary meetings were held in person.

The focus of the ordinary meetings in the 
financial year 2023 was on deliberations 
regarding the continued development of the 
Company’s business related to the Pfizer- 
BioNTech COVID-19 vaccine and the 
associated strategic decisions regarding 
adaptations to the Omicron variant and its 
sublineages, as well as decisions with regards 

to production, supply, delivery, and distribution 
of the vaccine worldwide. In addition, a focus 
was placed on deliberations regarding the 
Company’s pipeline development in the areas of 
oncology and infectious diseases as well as on 
the completion of new strategic collaborations.

The Supervisory Board was also involved  
in decisions about the strengthening and  
extension of the developed corporate strategy, 
including the growth of the Company and the 
accompanying expansion into various regions 
worldwide.

In addition to the focus topic of the COVID-19 
vaccine business and the pipeline expansion in 
the areas of oncology and infectious diseases, 
the Supervisory Board addressed the following 
topics during the 2023 financial year:

   Review of production of the COVID-19 
vaccine, as well as its commercialization, 
network development, creation of a 
development plan adapted to changing 
population health needs worldwide, 
national and international distribution as 
well as facilitating global availability of the 
COVID-19 vaccine; 

   Review of the expansion of distribution 
and commercialization of the COVID-19 
vaccine and support of global vaccine 
supply to populations by entering into  
supply agreements as well as collaboration 

agreements with multiple companies and 
governments worldwide; 

   Review of the advancement of the 
diversified portfolio of oncology product 
candidates and the achievement of clinical 
trial milestones in the areas of oncology 
and immunology, and development of IT 
processes to support clinical development; 

   Review of strategy, structure and  
process development in the areas of com-
mercialization, communication, digitization 
and cooperations at the respective sites; 

   Review of the expansion of laboratory  
and production capacity and office  
space, as well as the development of new  
manufacturing facilities to expand produc-
tion and distribution capacity worldwide, 
including development and construction of 
BioNTainers intended to expand vaccine 
production worldwide; 

   Review of the Company’s global growth 
and related measures, such as site expan-
sion in Africa, Asia and Australia; 

   Review of and participation in public- 
private partnerships to advance the devel-
opment of immunotherapies through the 
expansion of clinical trials;

BioNTech | Annual Report 202335

   Monitoring the Company’s financing 
activities; 

   Completion of several collaborations, 
investments and licensing agreements,  
in particular with regard to strategic  
rationales; 

   Review of the established terms and 
parameters for determining the restricted 
stock units, or RSUs, announced in January 
2024 under the BioNTech Employee 2020 
Long-Term Equity Plan (“BioNTech Employee 
2020 Equity Plan”) for employees; 

   Setting the agenda and review of the 
draft resolutions for the 2023 Annual  
General Meeting; 

   Review and appraisal of the compensation 
granted and owed in the 2023 financial 
year and of the compensation system 
applied as part of the compensation report 
pursuant to Section 162 of the German 
Stock Corporation Act (AktG); 

   Review and monitor the achievement of 
the Company’s 2023 goals and the setting 
of the budget for the 2024 financial year; 

   Review and discussion of the financial 
statements and the combined manage-
ment report for BioNTech SE and the 
Group;

   Review and discuss the effectiveness of 
the internal control system and risk man-
agement as well as the results of the annual 
auditor’s review; 

   Consideration of all corporate gover-
nance issues and review of compliance with 
the recommendations of the Corporate 
Governance Code both in and after the 
2023 financial year; and 

   Discussion and review of the Company’s 
sustainability report.

COMMITTEES //
To implement its monitoring and advisory  
function, the Supervisory Board has formed 
three committees: an Audit Committee, a 
Compensation, Nomination and Governance 
Committee, and a Capital Markets Committee. 
The above-mentioned key topics were  
prepared by the committees, including the 
associated resolutions and issues, for subse-
quent consideration by the full Supervisory 
Board. Effective October 01, 2023, a new 
Product Committee was established.

The Audit Committee consisted of Prof.  
Anja Morawietz, Ph.D., Ulrich Wandschneider 
and Rudolf Staudigl throughout the 2023 
financial year. Anja Morawietz is the Chair  
of the Audit Committee. In particular, the  
Audit Committee deals with monitoring the  
Company’s accounting, monitoring the  

BioNTech | Annual Report 202336

establishment and effective functioning of 
internal controls over financial reporting, 
monitoring compliance with SOX regulations 
(Sarbanes-Oxley Act Section 404), and  
monitoring the establishment and effective 
functioning of the risk and compliance man-
agement system and the internal auditing 
system. For the quarterly financial statements 
as of March 31, June 30, and September 30, 
2023, as well as the annual financial state-
ments as of December 31, 2023, the Audit 
Committee held discussions with the auditors 
and representatives of the accounting depart-
ment, discussed the key points of the audit, 
and discussed the publications in detail with 
the Management Board. For reports requiring 
approval by the Supervisory Board, the Audit 
Committee prepared the resolutions for the 
Supervisory Board’s decision. The Committee 
met eight times in the 2023 financial year. Of 
these, a total of four meetings were held in 
person, three as hybrid meetings, and one 
meeting took place as a video conference. 
Ulrich Wandschneider was unable to attend 
one meeting; otherwise, all members of the 
Audit Committee attended all meetings.

All members of the Audit Committee qualify as 
“independent directors” for the financial year 
2023 within the meaning of Rule 10A-3 under 
the U.S. Securities Exchange Act of 1934, as 
amended (the “Exchange Act”) and Nasdaq 
Listing Rule 5605. In addition, all members have 
qualified as “audit committee financial experts” 

as defined under the Exchange Act. In addition, 
all members also have the special knowledge 
and experience in the field of accounting as well 
as expertise in the field of auditing as required 
by the German Corporate Governance Code. 
This includes knowledge and experience in the  
application of accounting principles and internal 
control and risk management systems, and 
special knowledge and experience in auditing 
financial statements. Anja Morawietz and  
Ulrich Wandschneider also possess knowledge 
of sustainability reporting and auditing.

Throughout the financial year 2023, Rudolf 
Staudigl and Michael Motschmann were  
members of the Compensation, Nominating 
and Corporate Governance Committee.  
Until May 25, 2023, Christoph Huber was  
part of the Committee. Since May 25, 2023, 
Nicola Blackwood has replaced Christoph 
Huber on this Committee. Rudolf Staudigl is 
the Chair of the Committee. The Compensa-
tion Committeedeals with fundamental issues 
relating to the compensation and determina-
tion of the salaries of the Management Board, 
and with the compensation of the Supervisory 
Board as well as the employee stock option 
programs. In the financial year 2023, it focused 
on the elections to the Supervisory Board 
and the implementation of new Management 
Board contracts to be concluded in 2023.  
For the new and re-elections of the Supervi-
sory Board, the Committee made proposals to 
the full Supervisory Board. Furthermore, the 

Compensation, Nomination and Corporate  
Governance Committee reviewed the com-
pensation system for the Management Board 
and Supervisory Board members by com-
missioning external consultants to conduct a 
benchmark analysis and discussed the result 
as well as possible future adjustments. In 
addition, the Committee held discussions to 
determine corporate goals, which were then 
discussed by the full Supervisory Board. The 
actual application of the compensation system 
in the 2023 financial year was assessed 
in the form of the compensation report in 
accordance with Section 162 of the German 
Stock Corporation Act (AktG). In the financial 
year 2023, the Committee also addressed 
the requirements for implementing a share 
repurchase program and discussed the 
introduction of shareholder guidelines with 
the Management Board. Additional possible 
performance-based employee shareholder 
programs which are in line with corporate 
objectives were discussed. In addition, the 
Committee addressed the development of 
a corporate governance standard for the 
Company that meets the requirements of both 
Nasdaq Global Select Market and the German 
Corporate Governance Code. The Committee 
met seven times during the 2023 financial year. 
The seven meetings took place as video con-
ferences. Three meetings were only attended 
by Michael Motschmann and Rudolf Staudigl. 
All other meetings were attended by all mem-
bers of the Committee.

BioNTech | Annual Report 202337

The Capital Markets Committee consisted 
of me, Helmut Jeggle, Michael Motschmann, 
and Anja Morawietz throughout the financial 
year 2023. To this day, I continue to act as 
Chair  of the Committee. The Capital Markets 
Committee advised the Supervisory Board 
on capital market measures which took place 
during the 2023 financial year, in particular 
measures taken to integrate InstaDeep 
following its acquisition, as well as other 
potential takeover, merger and acquisition 
activities. In the financial year 2023, the Com-
mittee also focused on the regular analysis 
of the Company’s investor structure, investor 
expectations regarding BioNTech and their 
goals for the financial year 2023 as well as 
feedback from investors. The Committee held 
discussions on strategic corporate planning, 
share price performance, and analyst ratings. 
The Committee also held discussions on indi-
vidual targets of potential M&A transactions, 
regularly discussed updates on planned 
or ongoing transactions, and engaged in 
discussions on the topic of communicating 
with investors. The Committee met four times 
during the 2023 financial year. All of these 
meetings took place as video conferences. 
All members of the Committee took part in all 
meetings.

Following extensive discussions in the Su-
pervisory Board and two strategy workshops 
with the Management Board, it was decided 
to establish a new Product Committee. This 

Committee was formally formed on October 1, 
2023. Its members are Ulrich Wandschneider, 
Nicola Blackwood and me, Helmut Jeggle. 
Ulrich Wandschneider serves as Chair of  
this Committee. The Product Committee’s  
responsibilities include strategy, execution 
and communications advice in relation to 
relevant launch efforts as well as overseeing 
activities related to product development, 
launch plans and their implementation. 
Special attention is given to advising on 
the market potential of products in clinical 
development. Prior to the establishment of 
the Product Committee, several preliminary 
discussions were held between the members 
of the Committee and Ugur Sahin, a represen-
tative of the Management Board, to define the 
structure and responsibilities of the Product 
Committee. The Committee met once in the 
2023 financial year. During this meeting, the 
focus was on discussing future work priorities, 
setting strategic goals, and laying the founda-
tion for next steps. All members of the Commit-
tee took part in this in-person meeting.

CORPORATE GOVERNANCE //
Together with the Management Board,  
we thoroughly examined the recommenda-
tions of the Corporate Governance Code. 
BioNTech adheres to the recommendations 
of the Corporate Governance Code with the 
exception of the provisions explicitly listed 
in the Declaration of Conformity pursuant to 
Section 161 of the German Stock Corporation 

BioNTech | Annual Report 202338

Act (AktG) dated February 27, 2024, and for 
which an explanation is provided as to why 
these are not complied with. We will continue to 
support the Management Board in its efforts 
to fully comply with the recommendations of 
the German Corporate Governance Code in 
the future.

CONFLICTS OF INTEREST ON THE SUPER- 
VISORY BOARD AND MANAGEMENT 
BOARD, SELF-ASSESSMENT, FURTHER 
TRAINING AND COMPETENCE PROFILE //
Conflicts of interest of Supervisory Board 
and Management Board members that may 
arise, for example, as a result of a consultancy 
or board function with customers, suppliers, 
lenders or other third parties, are disclosed in 
the interests of good corporate governance. 
There were no potential conflicts of interest 
for the Supervisory Board and Management 
Board in the 2023 financial year. Accord-
ingly, neither the Supervisory Board nor the 
Management Board members waived their 
right to participate in the discussion of indi-
vidual agenda items or to vote on the relevant 
resolutions.

As members of the Supervisory Board, we 
regularly participated in training and further 
education measures in the 2023 financial 
year. This included, e.g., various workshops 
and training events on topics relevant to 
the Company. In addition, the Supervisory 
Board received training from an external legal 

advisor commissioned by the Company on 
the topics of sustainability/CSR, cybercrime 
and common corporate risks. After the end 
of the financial year, the Supervisory Board 
conducted a self-assessment by completing 
a written questionnaire to evaluate the meth-
ods used by the Supervisory Board and the 
collaboration with the Management Board. 
This evaluation covered all key aspects of 
the Supervisory Board’s work, including 
its committees, composition, competence 
profile, main topics, and its relationship with 
the Management Board. Following the evalu-
ation of this self-assessment, the work of the 
Supervisory Board, its committees and the 
Management Board remains professional and 
cooperative. No fundamental need for change 
was identified.

The Supervisory Board established a compe-
tency profile for the entire body, which covers 
various specialist areas. As the Supervisory 
Board, we ensure that the competency profile 
is met by our members and updated as nec-
essary. In addition, the Supervisory Board al-
ways endeavors to fill this competency profile 
when appointing members to the full body.

ANNUAL AND CONSOLIDATED  
FINANCIAL STATEMENTS AUDIT //
In accordance with the resolution of the 
Annual General Meeting on May 25, 2023, 
the Supervisory Board has commissioned 
EY GmbH & Co. KG Wirtschaftsprüfungs-

gesellschaft to audit the annual financial 
statements for the 2023 financial year.

The audit includes:

   the annual financial statements of  
BioNTech SE in accordance with HGB; 

   the report on relations with affiliated 
companies pursuant to Section 313 para. 
1 of the German Stock Corporation Act 
(AktG), the so-called dependency report; 

   the consolidated financial statements 
prepared in accordance with Section 315e 
para. 3 in conjunction with para. 1 HGB on 
the basis of International Financial Reporting 
Standards (IFRS) as adopted by the EU; 

   the consolidated financial statements, 
which have been prepared in accordance 
with IFRS as issued by the International 
Accounting Standards Board (IASB) and 
filed on Form 20-F with the U.S. Securities 
Exchange Commission after our approval; 

   the combined management report; and 

   the audit of the internal control system.

The financial statements prepared by the 
Management Board on March 18, 2024, 
i.e., the annual financial statements and the 
dependency report of BioNTech SE, and the 

BioNTech | Annual Report 202339

consolidated financial statements and the 
management report for the Group and the 
Company for the 2023 financial year, were 
submitted to all members of the Supervisory 
Board.

Together with the Management Board, we 
prepared a compensation report for the first 
time for the 2023 financial year in accor-
dance with Section 162 of the German Stock 
Corporation Act (AktG), which was adopted 
on March 18, 2024, and is disclosed as a 
separate report. 

We also received the auditors’ reports on 
the accounting records, the annual financial 
statements, the dependency report, the 
consolidated financial statements as well as 
the management report on the Group and the 
Company for the financial year 2023, each of 
which was issued with an unqualified opinion 
on March 20, 2024. The auditors’ report was 
discussed by the Audit Committee with the 
Management Board and the auditors. The 
Audit Committee particularly focused on 
key audit matters described in the auditors’ 
report, including the audit procedures per-
formed. This was followed by a discussion in 
the Supervisory Board. 

On our part, we have audited the annual 
financial statements, the dependency report, 
the consolidated financial statements and the 
management report for the Group and the 

Company for the 2023 financial year.

Based on the final results of our audit, we 
have no objections to raise. We consider the 
auditor’s assessment of the annual financial 
statements to be accurate. We approve the 
annual financial statements and the consol-
idated financial statements prepared by the 
Management Board. The former is thus ad-
opted. The Supervisory Board also concurs 
with the management report on the Group 
and the Company. Based on the final result of 
its examination, the Supervisory Board also 
has no objections to the declaration by the 
Management Board on relations with affiliated 
companies in the dependency report.

EXPRESSION OF GRATITUDE OF THE 
SUPERVISORY BOARD //
Last year, BioNTech set important milestones 
for the future. The Company plans to drive 
clinical development in the field of oncology 
towards potential approvals. In addition, it 
is addressing infectious diseases with high 
medical need with its vaccine candidates. 

As often is the case, success like this comes 
from the sum of several things. 

The Supervisory Board would like to thank the 
investors for their trust, the members of BioN-
Tech’s Management Board and all employees 
across the globe for their performance over 
the past year.

BioNTech | Annual Report 202340

With great commitment, passion and an  
unwavering belief in the Company’s vision, 
they have contributed significantly to its  
success and have always collaborated with 
the Company’s corporate bodies.

Munich, March 20, 2024
BioNTech SE

Helmut Jeggle
Chairman of the Supervisory Board

BioNTech | Annual Report 2023FROM FOUNDING  
VISION TO GLOBAL 
IMPACT 

41

BioNTech’s  
15-year journey

BioNTech | Annual Report 202342

2023 was a special year for us at BioNTech as it marked our 15th anniversary – a 
moment to reflect on our remarkable journey from a small, privately owned startup 
to a global, fully integrated immunotherapy Company.

There are many milestones that make BioNTech’s story unique. Groundbreaking 
scientific discoveries, combined with unwavering determination result in profound 
biopharmaceutical innovation. We were the first to develop an intravenously  
delivered mRNA-based human therapeutic, the first to advance an individualized 
mRNA-based cancer immunotherapy into clinical trials, and the first to establish 
scaled in-house manufacturing for such a product candidate.

BioNTech | Annual Report 202343

2008

FOUNDING OF THE COMPANY //
BioNTech was founded in 2008 by medical 
doctors and scientists Ugur Sahin, Özlem 
Türeci and Christoph Huber. They were 
driven by the vision to translate scientific 
discoveries into life-saving treatments. The 
founding also involved Andreas and Thomas 
Strüngmann, the MIG funds, and Chairman of 
the Supervisory Board Helmut Jeggle. They 
supported the founding idea with seed financing 
of $180 million. Profs. Sahin and Türeci had 
already spent decades researching innovative 
potential treatment options to address cancer 
at this point. With BioNTech, they sought to 
advance this research and develop potential 
individualized mRNA-based cancer vaccines 
and other precision cancer treatments. 

CHRISTOPH HUBER
Pioneering hematologist, oncologist, 
and translational immunologist Prof. 
Christoph Huber, M.D. co-founded 
BioNTech and served as a member 
of the Company’s Supervisory Board 
until his retirement in 2023. With 
his many years of dedication, his 
passion, and his pioneering spirit, he 
made decisive contributions to the 
translation of scientific research into 
practical applications, such as the 
characterization of surface struc-
tures of cancer cells, throughout his 
career and contributed significantly 
to the diversified pipeline the Compa-
ny can draw on today. 

2012

INITIATION OF FIRST  
CLINICAL TRIAL // 
In 2012, we started our first Phase 1 clinical 
trial with an RNA immunotherapy in melanoma. 
While every patient’s tumor is unique,  
tumors can share certain sets of markers, 
known as antigens, that are not found in 
healthy cells. This is the idea behind one of 
our mRNA-based immunotherapy approach-
es, now known as FixVac. In a Phase 1 clinical 
trial, which BioNTech initiated in 2015, pa-
tients with melanoma were treated with one of 
these FixVac investigational candidates; the 
first results of the trial were published in the 
high-ranking journal Nature in 2020.

KATALIN KARIKÓ
mRNA scientist Prof. Katalin (Kati) 
Karikó first met the BioNTech team in 
2013 and decided to join the Company 
shortly afterward. Like Ugur Sahin 
and Özlem Türeci, she believed in the 
potential of mRNA from the very  
beginning and focused on improving 
the therapeutic potential of the mol-
ecule. In 2014, the three scientists 
published their findings in a compre-
hensive overview in Nature Reviews 
Drug Discovery. In 2023, Kati Karikó 
and her colleague Drew Weissman 
from the University of Pennsylvania 
received the Nobel Prize in Physiology 
or Medicine for pioneering  
nucleoside base modifications, 
which were one of the key innova-
tions applied to develop the Pfizer- 
BioNTech COVID-19 vaccine. 

BioNTech | Annual Report 20232014

FIRST TRIAL WITH FULLY INDIVIDUALIZED  
mRNA VACCINE CANDIDATE //
We took a decisive step towards potential  
individualized cancer therapies in 2014 by  
initiating the first Phase 1 clinical trial with our  
individualized mRNA-based immunotherapy  
approach, called iNeST (individualized  
neoantigen specific immunotherapy). Results 
were published three years later in Nature. 

44

2015

SEAN MARETT
Sean Marett joined BioNTech in 2012 
and played a crucial role in ensuring 
BioNTech’s liquidity in the early  
stages of development and support-
ing its growth. He successfully  
executed BioNTech’s first collab-
oration agreement in his first year, 
followed by numerous revenue- 
generating agreements with high- 
profile pharmaceutical companies. 
Sean’s outstanding negotiation and 
leadership skills have been instrumental 
in the Company’s transformation into 
a next-generation immunotherapy 
Company. 

EXPANDING OUR TOOLKIT // 
We started to expand our toolkit in 2015. 
Cancer is not just one disease, but many.  
Cancer differs from patient to patient and 
even within a patient’s tumor there are 
different cancer cells. This is why there is no 
one-size-fits-all approach to treating cancer 
that works for all patients. A whole toolkit of 
therapeutic approaches is needed. We at  
BioNTech are developing our proprietary 
technologies and are also teaming up with 
other organizations to build such a toolkit. In 
2015, we entered into a collaboration with 
Genmab to jointly research and develop novel 
mono- and bispecific cancer antibodies. Many 
more collaborations have followed in the 
years to come. Today, we work together with 
Genmab, DualityBio, Genentech, Genevant, 
OncoC4, Regeneron, Pfizer, and others. 

Together, we have developed a diversified 
toolkit consisting of platform technologies 
with combinational and synergistic potential 
which we evaluate in clinical trials, including 
mRNA therapeutics, cell therapies, and  
protein-based precision therapeutics.

BioNTech | Annual Report 20232018

SERIES A FINANCING ROUND //
We secured a Series A funding of $270 
million in 2018. As part of the financing, we 
gained additional investors who believed in 
BioNTech and our vision. They supported our 
global expansion and the accelerated devel-
opment of our unique oncology pipeline with 
precision and personalized candidates. 

2019

INITIAL PUBLIC OFFERING // 
Our Initial Public Offering (IPO) was in 2019. 
With gross proceeds of $150 million, we have 
since been listed on the NASDAQ Global Select 
Market under the ticker symbol “BNTX”.

2019

2020

45

PROJECT LIGHTSPEED // 
2020 changed everything – but not our  
vision. Our scientists decided decades ago  
to develop mRNA as a flexible platform tech-
nology. They saw the potential of mRNA as a 
technology for the treatment of cancer and as 
a vaccine against infectious diseases. At the 
beginning of 2020, we started the develop-
ment of our COVID-19 vaccine, an endeavor 
we called Project Lightspeed. Our goal was 
to develop a safe and effective vaccine 
against COVID-19. Simultaneously, we  
enhanced our manufacturing capacities  
by acquiring our site in Marburg, which we  
expanded to become one of the largest mRNA 
manufacturing facilities in Europe in 2021. 

Within only 10 months we developed the  
Pfizer-BioNTech COVID-19 Vaccine, eval-
uated it in large clinical trials, and received 
(emergency or conditional) approval from 
authorities in different countries. For us at  
BioNTech, this was a tremendous success, 
as it was not only the fastest vaccine devel-
opment against a new pathogen in medical 
history, but also proof that mRNA can become 
a new drug class.

BioNTech | Annual Report 202346

2021

RE-FOCUS ON FIGHT  
AGAINST CANCER //
In 2021, we refocused on our roots by 
reinforcing our development of cancer 
therapies that can also be combined with 
each other. We used our resources to 
further accelerate the development of our 
cancer treatment candidates. This included 
the treatment of the first colorectal cancer 
patient in a Phase 2 trial with an individual-
ized cancer vaccine candidate. In addition, 
we acquired a new manufacturing site in 
Gaithersburg in the US to expand our clinical 
production capacities for cell therapies. In 
parallel, we continued our work to develop 
novel COVID-19 vaccines. 

2022

INTRODUCTION OF OUR BIONTAINERS //
We introduced a new global manufacturing 
approach for mRNA-based products in 2022. 
Our container-based, modular BioNTainers 
 are designed to enable the scalable produc-
tion of mRNA-based medicines. The ground-
breaking for the first BioNTainer-based facility 
was held in Rwanda in the same year. Ground-
breaking for a BioNTainer-based facility in 
Melbourne, Australia, is intended to follow in 
2024.

BioNTech | Annual Report 202347

After 15 years of in parts invisible advance-
ments, 2023 was marked by a number of sig-
nificant milestones across various domains. 
As we turn the page to the next chapter, we 
will delve into the details of our anniversary 
year, exploring the impact of our work of 
the past year where we once again aimed 
at pushing the boundaries of science and 
making a difference in the lives of patients 
worldwide.

BioNTech | Annual Report 20232023 
HIGHLIGHTS 

48

BioNTech | Annual Report 2023 
49

CORPORATE DEVELOPMENT //

BioNTech signed a Memorandum of 
Understanding with the Government  
of the United Kingdom to benefit 
patients by expanding clinical trials for 
personalized mRNA immunotherapies 
with the aim to provide personalized 
cancer therapies for up to 10,000 
patients by the end of 2030, either  
in clinical trials or as authorized treat-
ments. The corresponding contracts 
were signed in July 2023.

JAN

BioNTech | Annual Report 2023INFECTIOUS DISEASES //

CORPORATE DEVELOPMENT //

5050

German Chancellor Olaf Scholz  
visited BioNTech in Marburg, Germany, 
as we completed the construction 
of our first proprietary plasmid DNA 
manufacturing facility. Plasmid DNA 
is an important starting material for 
the manufacturing of mRNA-based 
vaccines and therapies, as well as  
cell therapies.

Pfizer and BioNTech started a Phase 
1/2 trial exploring the safety, tolerability, 
and immunogenicity of the companies’ 
mRNA vaccine program BNT167 
against shingles.

FEB

BioNTech | Annual Report 202351

CORPORATE DEVELOPMENT //

BioNTech signed a Memorandum of  
Understanding with the Weizmann  
Institute of Science in Israel, under 
which scientists from BioNTech and 
the Weizmann Institute would collabo-
rate on basic and applied research with 
the aim of better understanding various 
diseases, including cancer.

We entered into a license and col-
laboration agreement with OncoC4 
to co-develop and commercialize 
the monoclonal antibody candidate 
BNT316/ONC-392 (gotistobart) as  
monotherapy or combination therapy 
in various cancer indications.

05

MAR

BioNTech | Annual Report 202352

CORPORATE DEVELOPMENT //

BioNTech formed a global strategic  
partnership with Duality Biologics to  
accelerate the development of differen-
tiated ADC therapeutics for solid  
tumors. This agreement further  
expanded BioNTech’s clinical-stage  
oncology portfolio with a new class of 
precision medicine therapeutics  
expanding the breadth of its immuno-
therapy toolkit with synergistic potential.

APR

BioNTech | Annual Report 202353

CORPORATE DEVELOPMENT //

Baroness Nicola Blackwood was elected 
to BioNTech’s Supervisory Board, 
succeeding Prof. Christoph Huber, 
M.D., who left the Supervisory Board 
after reaching the retirement age limit. 
Supervisory Board members Michael 
Motschmann and Ulrich Wandschneider, 
Ph.D., were reappointed.

MAY

BioNTech | Annual Report 202354

ONCOLOGY //

The first patient with NSCLC was  
treated in a pivotal Phase 3 trial  
evaluating BioNTech’s and OncoC4’s 
antibody candidate BNT316/ 
ONC-392 (gotistobart). The initiation 
of the trial was based on positive safety 
and efficacy data from a Phase 1/2 
study with BNT316/ONC-392  
alone and in combination with  
pembrolizumab in patients with 
advanced solid tumors. Follow-up 
data from this trial presented at the 
ASCO 2023 Annual Meeting showed 
encouraging anti-tumor activity and a 
manageable safety profile in a patient 
cohort with metastatic, anti-PD-(L)1- 
resistant NSCLC.

JUN

BioNTech | Annual Report 202355

CORPORATE DEVELOPMENT //

BioNTech closed its acquisition of 
InstaDeep, a leading global technol-
ogy company in the field of AI and 
machine learning. The acquisition 
supports BioNTech’s strategy to 
build world-leading capabilities 
in AI-driven drug discovery and 
development of next-generation 
immunotherapies and vaccines to 
address diseases with high unmet 
medical need. 

JUL

BioNTech | Annual Report 202356

INFECTIOUS DISEASES //

Pfizer and BioNTech received approvals 
for individuals 12 years and older for their 
Omicron XBB.1.5-adapted monovalent 
COVID-19 vaccine in various markets, 
including the United States, Europe,  
Canada and Japan.

AUG/SEP

BioNTech | Annual Report 2023INFECTIOUS DISEASES //

CORPORATE DEVELOPMENT //
CORPORATE DEVELOPMENT

57

BioNTech and the Coalition for  
Epidemic Preparedness Innovations 
(CEPI) formed a strategic partnership  
to advance mRNA-based vaccine candi-
dates with the development of BNT166 
for the prevention of mpox. CEPI agreed 
to provide funding of up to $90 million  
to support the development of mRNA- 
based vaccine candidates.

SEP

The Supervisory Board appointed 
James Ryan, Ph.D., to the Management 
Board as Chief Legal Officer. As part of 
the Management Board, James Ryan 
has continued to lead the Company’s 
corporate legal strategy and global legal 
operations including transactions,  
corporate governance, securities,  
intellectual property (IP), insurance,  
data privacy, among others. 

BioNTech | Annual Report 202358

ONCOLOGY //

BioNTech expanded its late-stage 
oncology portfolio: The first patient 
was treated in a Phase 2 clinical trial 
evaluating the mRNA-based individ-
ualized cancer vaccine candidate 
BNT122 in resected pancreatic 
ductal adenocarcinoma (PDAC).

We presented data across our 
oncology pipeline, covering multiple 
solid tumor types and novel mecha-
nisms of action, at the ESMO  
Congress, including data from 
a Phase 1/2 trial for cell therapy 
candidate BNT211. BNT211 is being 
evaluated alone and in combination 
with an investigational CAR-T cell 
Amplifying RNA Vaccine (CARVac) in 
patients with solid tumors. The data 
showed encouraging signs of clinical 
activity and an increased  
persistence of cancer-specific 
CAR-T cells in the combinatory  
setting. In course of the dose esca-
lation, a dose-dependent increase in 
adverse events was observed. In most 
cases, these were of grade 1 and 2.  

We presented data updates at the 
SITC Annual Meeting across multiple 
immuno-oncology programs, such 
as mRNA-based cancer vaccine 
candidates, investigational antibodies 
and cell therapies. 

OCT

BioNTech | Annual Report 2023ONCOLOGY //

CORPORATE DEVELOPMENT //

59

Together with our collaborator Duality 
Biologics, we were granted Break-
through Therapy designation by the 
FDA for their investigational ADC 
BNT323/DB-1303 for the treatment 
of advanced endometrial cancer. 

DEC

BioNTech and the State of Victoria 
in Australia signed a multi-year stra-
tegic partnership to strengthen the 
local mRNA ecosystem and facilitate 
innovations deriving from it. This 
partnership is aimed at providing 
high-tech manufacturing capabilities 
and expertise to curate encouraging 
projects for further R&D.

We inaugurated our site in Kigali, 
Rwanda. The inauguration took place 
on the occasion of the set-up of the 
first BioNTainer, which was flown to 
Kigali, Rwanda, in March 2023.

From left to right: John Nkengasong, Africa CDC; 
Sierk Poetting, BioNTech; Ugur Sahin,  
BioNTech; H.E. Ursula von der Leyen, President 
of the European Commission; H.E. Macky Sall, 
former President of the Republic of Senegal; 
H.E. Paul Kagame, President of the Republic of 
Rwanda; H.E. Nana Akufo-Addo, President of the 
Republic of Ghana; Hon. Mia Amor Mottley, Prime 
Minister of Barbados; H.E. Annalena Baerbock, 
Federal Minister of Foreign Affairs of the Federal 
Republic of Germany.

BioNTech | Annual Report 2023 
FINANCIAL  
CALENDAR 2024

60

MAY  6

MAY  17

AUG  5

OCT  1

NOV  4

NOV  14

FIRST QUARTER 
EARNINGS

ANNUAL GENERAL 
MEETING

SECOND QUARTER  
EARNINGS

INNOVATION SERIES  
(DIGITAL & AI DAY)

THIRD QUARTER  
EARNINGS

INNOVATION SERIES 

IMPRINT //
BioNTech SE 
An der Goldgrube 12 
55131 Mainz, Germany
Tel.: +49-6131-9084-0 
Fax: +49-6131-9084-390 
Email: info@biontech.de 

CORPORATE  
COMMUNICATIONS //
Tel.: +49-6131-9084-1513 
Email: media@biontech.de 

CONCEPT, VISUAL  
DESIGN AND 
RENDERINGS // 
heureka GmbH, Essen

PHOTOGRAPHY/ 
COPYRIGHT // 
BioNTech SE

DISCLAIMER //
Date of publication:  
April 8, 2024.
References were drawn at the 
time of publication; we take no 
responsibility for the content of 
external sources. The English 
translation of the annual report is 
provided for convenience only. 
The German original is definitive.

BioNTech | Annual Report 202361

FORWARD -LOOKING STATEMENTS //
This document contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, but not limited to, statements concerning: BioNTech’s expected revenues and net profit 
related to sales of BioNTech’s COVID-19 vaccine, referred to as COMIRNATY where approved for use under full or conditional marketing authorization, in territories controlled by BioNTech’s collaboration partners, particularly for those figures 
that are derived from preliminary estimates provided by BioNTech’s partners; the rate and degree of market acceptance of BioNTech’s COVID-19 vaccine and, if approved, BioNTech’s investigational medicines; expectations regarding antic-
ipated changes in COVID-19 vaccine demand, including changes to the ordering environment and expected regulatory recommendations to adapt vaccines to address new variants or sublineages; the initiation, timing, progress, results, and 
cost of BioNTech’s research and development programs, including those relating to additional formulations of BioNTech’s COVID-19 vaccine, and BioNTech’s current and future preclinical studies and clinical trials, including statements regard-
ing the timing of initiation, enrollment, and completion of studies or trials and related preparatory work and the availability of results, and the timing and outcome of applications for regulatory approvals and marketing authorizations; BioNTech’s 
expectations with respect to its intellectual property; the impact of BioNTech’s collaboration and licensing agreements and its acquisition of InstaDeep Ltd.; the development, nature and feasibility of sustainable vaccine production and supply 
solutions; and BioNTech’s estimates of revenues, research and development expenses, cost of sales, general and administrative expenses, and capital expenditures for operating activities. In some cases, forward-looking statements can be 
identified by terminology such as “will,” “may,” “should,” “expects,” “intends,” “plans,” “aims,” “anticipates,” “believes,” “estimates,” “predicts,” “potential,” “continue,” or the negative of these terms or other comparable terminology, although not all 
forward-looking statements contain these words. The forward-looking statements in this press release are neither promises nor guarantees, and you should not place undue reliance on these forward-looking statements because they involve 
known and unknown risks, uncertainties, and other factors, many of which are beyond BioNTech’s control and which could cause actual results to differ materially from those expressed or implied by these forward-looking statements.

These risks and uncertainties include, but are not limited to: BioNTech’s pricing and coverage negotiations regarding its COVID-19 vaccine with governmental authorities, private health insurers and other third-party payors after BioNTech’s 
initial sales to national governments; the future commercial demand and medical need for initial or booster doses of a COVID-19 vaccine; competition from other COVID-19 vaccines or related to BioNTech’s other product candidates, including 
those with different mechanisms of action and different manufacturing and distribution constraints, on the basis of, among other things, efficacy, cost, convenience of storage and distribution, breadth of approved use, side-effect profile and 
durability of immune response; the timing of and BioNTech’s ability to obtain and maintain regulatory approval for BioNTech’s product candidates; the ability of BioNTech’s COVID-19 vaccines to prevent COVID-19 caused by emerging virus 
variants; BioNTech’s and its counterparties’ ability to manage and source necessary energy resources; BioNTech’s ability to identify research opportunities and discover and develop investigational medicines; the ability and willingness 
of BioNTech’s third-party collaborators to continue research and development activities relating to BioNTech’s development candidates and investigational medicines; the impact of the COVID-19 pandemic on BioNTech’s development 
programs, supply chain, collaborators and financial performance; unforeseen safety issues and potential claims that are alleged to arise from the use of BioNTech’s COVID-19 vaccine and other products and product candidates developed or 
manufactured by BioNTech; BioNTech’s and its collaborators’ ability to commercialize and market BioNTech’s COVID-19 vaccine and, if approved, its product candidates; BioNTech’s ability to manage its development and expansion; regulatory 
developments in the United States and other countries; BioNTech’s ability to effectively scale its production capabilities and manufacture its products, including target COVID-19 vaccine production levels, and product candidates; risks relating 
to the global financial system and markets; and other factors not known to BioNTech at this time.

You should review the risks and uncertainties described under the heading “Risk Factors” in BioNTech’s annual report on Form 20-F for the year ended December 31, 2023 and in subsequent filings made by BioNTech with the SEC, which 
are available on the SEC’s website at https://www.sec.gov/. Except as required by law, BioNTech disclaims any intention or responsibility for updating or revising any forward-looking statements contained in this document in the event of new 
information, future developments or otherwise. These forward-looking statements are based on BioNTech’s current expectations and speak only as of the date hereof.

BioNTech | Annual Report 202362

COMBINED  
MANAGEMENT  
REPORT 2023

mRNA is a natural information molecule 
that is translated to proteins. A protein that 
belongs to the body will have a specific 
function in the cell, while the protein that 
does not belong to the body can serve as 
a lesson to the immune system about what 

should be eliminated.   2

BioNTech | Annual Report 20231  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

63

1  GENERAL INFORMATION  
ON THE BioNTech GROUP

Pursuant to Section 315 para. 5 of the German Commercial Code (HGB) 
in conjunction with Section 298 para. 2 HGB, this combined management 
report comprises both the group management report of BioNTech SE 
and its group companies (together “BioNTech” or the “Group”) and the 
management report of BioNTech SE (also “the Company”), hereinafter 
also referred to as “BioNTech”, the “Group”, “we” or “us”. The combined 
management report has been prepared in accordance with the Regula-
tion on the Statute for a European Company (SE) in conjunction with the 
German Stock Corporation Act (AktG). The comments on the Group have 
been prepared in accordance with the International Financial Reporting 
Standards (IFRS) as adopted by the European Union; the comments on 
BioNTech SE have been prepared in accordance with the German Com-
mercial Code (HGB). Unless otherwise stated, the statements in the com-
bined management report relate to both the Group and BioNTech SE. In 
addition to the reporting on the Group, the development of BioNTech SE 
is explained in Section 3.

We prepare and publish our combined management report in euros and 
round figures to the nearest thousand or million euros. Accordingly, the 
figures presented as totals or as percentages in some tables may deviate 
slightly and the figures presented in the notes may not add up exactly to 
the totals presented.

1.1 Business Model

We are a global immunotherapy company pioneering the development 
of novel medicines against cancer, infectious diseases and other serious 
diseases. Our vision and mission are the same as when our Company was 
founded in 2008: We are committed to improving the health of people 
worldwide, harnessing the full potential of the immune system to develop 
drugs to fight diseases with high or unmet medical need.

Our fully integrated business model combines decades of research in 
immunology, translational drug discovery and development, technology- 
agnostic innovation, GMP manufacturing, artificial intelligence and ma-
chine learning, and commercial capabilities to develop and commercialize 
vaccines and therapies.

We have built a broad portfolio of product candidates across multiple 
technology platforms that encompass a diverse range of therapeutic ap-
proaches, including mRNA vaccines and therapeutics, cell and gene ther-
apies, protein-based therapeutics (including monospecific and bispecific 
antibodies and antibody-drug conjugates or ADCs), cell therapies and 
small molecules. We believe that harnessing complementary, potential-
ly  synergistic  modes  of  action  increases  the  likelihood  of  therapeutic 
success, reduces the risk of emergence of secondary resistance mech-
anisms and could also unlock a larger potential patient population. Crit-
ically, this approach allows us to pursue a technology-agnostic path by 
developing an appropriate therapeutic platform or a combination thereof 
for the intended patient and purpose.

We have continued to develop and diversify our pipeline. There are cur-
rently 22 product candidates in oncology and seven product candidates 
in infectious diseases in clinical development.

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64

In 2023, we remained committed to our goals and strengthened our tech-
nology platforms, our digital capabilities and our infrastructure through 
sustainable investments, strategic partnerships and tactical acquisitions 
to bring long-term value to patients and other stakeholder groups.

Leading the Development of COVID-19 Vaccines

In 2023, in partnership with Pfizer Inc., New York, United States (Pfizer), we 
developed an Omicron XBB.1.5-adapted monovalent COVID-19 vaccine 
and launched it in various markets worldwide. This is part of our efforts to 
build an enduring COVID-19 vaccine business.

Healthcare and Social Responsibility

We have made progress in making innovative medicines more acces-
sible  to  wider  populations  around  the  world:  In  2023,  more  than  30% 
of COVID-19 vaccine doses were delivered to low- and middle-income 
countries (LMICs) in line with demand. We work with NGOs, institutions 
and governments to provide more equitable access to novel medicines, 
especially in low- and middle-income countries and regions. In Decem-
ber 2023, we reached the next milestone in the establishment of mRNA 
vaccine manufacturing capacities in Africa with the inauguration of the 
our site in Kigali, Rwanda. We are progressing the development of mRNA 
vaccine candidates for infectious diseases with high medical need, in-
cluding vaccine candidates against tuberculosis, malaria, and HIV, as well 
as against infectious diseases with pandemic potential, such as mpox.

Innovative and Diversified Pipeline

We are working on the development of innovative drugs for diseases with 
high or unmet medical need. We continue to build our pipeline, which has 
grown in recent years in line with the Company’s fundamental vision of 
harnessing the power of the immune system to fight cancer and other 
serious diseases. In 2023, we commenced two Phase 3 trials in oncology, 

and we and our partners presented data on several product candidates 
at international medical meetings. We entered into four new collabora-
tions and in-licensed six product candidates in oncology, some of which 
have advanced rapidly to later-stage clinical trials, in 2023. For infectious 
diseases, we initiated three Phase 1 clinical trials for vaccine candidates 
based on our proprietary mRNA technology in 2023. These include prod-
uct candidates for a malaria vaccine, tuberculosis (in collaboration with 
the Bill & Melinda Gates Foundation) and mpox in partnership with the 
Coalition for Epidemic Preparedness Innovations (CEPI). 

Innovation at Scale

We are building and scaling biotech innovations with the aim of becoming 
a patient-centric multi-product company. We expanded our team globally 
in 2023 and attracted talent, including clinical and regulatory experts, 
to advance the development of our pipeline. Our diverse workforce rep-
resents more than 80 nations, and we have subsidiaries in 18 countries 
across five continents. In 2023, we expanded our organization in Asia, 
Africa, the United States, Australia and Europe. We increased our overall 
research and development and production capabilities, including com-
pleting construction of our first proprietary plasmid DNA manufacturing 
facility in Marburg, Germany. Furthermore, we established a corporate 
office in Shanghai, China, and inaugurated our site in Kigali, Rwanda, 
on the occasion of the set-up of the first manufacturing unit called BioN-
Tainer. With the acquisition of our long-time strategic collaboration partner 
InstaDeep, we have taken a further step in our strategy, aiming to build 
world-leading capabilities in AI-driven drug discovery and development of 
next-generation immunotherapies and vaccines to address diseases with 
high unmet medical need. The transaction adds approximately 290 highly 
skilled professionals to our organization.

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65

1.2 Legal and Organizational Structure

1.3 The BioNTech Approach

Legal Structure

BioNTech SE was founded in 2008 as a spin-off from Johannes Gutenberg 
University Mainz. The underlying broad technology and patent portfolio 
was built up over a period of more than 20 years.

BioNTech SE is the parent company of the BioNTech Group and is re-
sponsible for the management and development of the Group. BioNTech 
SE has its registered  office  in  Mainz, Germany (An der  Goldgrube  12, 
55131 Mainz). In addition, as of the end of the 2023 financial year, the 
 BioNTech Group included 41 group companies.

The shares of BioNTech SE are publicly traded as American Depositary 
Shares (ADSs), each of which represents one ordinary share, on the 
Nasdaq Global Select Market.

Organizational Structure

As the parent company of the BioNTech Group, BioNTech SE has a dual 
management system: The Management Board, as the managing body, 
had seven members as of December 31 and is appointed and monitored 
by the Supervisory Board. On May 3, 2023, our Supervisory Board ex-
panded our Management Board by appointing James Ryan as Chief Legal 
Officer (CLO), effective as of September 1, 2023. As CLO, James Ryan 
heads up our Legal department and is responsible for developing and 
leading the corporate legal strategy to promote and protect BioNTech’s 
global operations. His current appointment to our Management Board 
ends on December 31, 2027. The Supervisory Board is elected by the An-
nual General Meeting. During the year ended December 31, 2023, Nicola 
Blackwood was appointed to the Supervisory Board on May 25, 2023. 
She succeeded Christoph Huber, who left the Supervisory Board after 
reaching the applicable retirement age limit. As a result, the Supervisory 
Board consisted of six members as of the reporting date December 31, 
2023. As of the reporting date December 31, 2023, the Group had 6,292 
employees, 3,166 of them at BioNTech SE (December 31, 2022: 4,692, 
2,304 of them at BioNTech SE). An annual average of 5,640 people were 
employed in 2023, of which 2,882 were employed by BioNTech SE (previ-
ous year: 4,104, of which 1,936 were employed by BioNTech SE). 

We work on the development of next-generation immunotherapies by 
pursuing a strategy based on a technology-agnostic approach. Our key 
objectives are to build a sustainable respiratory vaccines business based 
on the BioNTech-Pfizer-Comirnaty franchise and to advance an innova-
tive oncology pipeline targeting multiple product approvals in the coming 
years. Our vision is to establish a multi-product company based on our 
technologies and science. In 2023, we expanded our access to a new 
technology – ADCs. We believe that this technology has the potential 
to replace highly toxic chemotherapy regimens in the long term and to 
become a new combination backbone of cancer treatment. Since our 
founding, we have been a multi-technology company. We believe that by 
combining complementary treatment modalities, we can leverage the 
potential of each technology to provide precise and personalized treat-
ments to patients. Our approach is based on the following principles:

  Exploiting the full potential of the immune system
Our pipeline comprises immunomodulators, including bispecific and 
monospecific antibodies, ADCs and cell therapies, including T-cell 
receptor and CAR-T cell therapies, as well as small molecules. Our 
broad clinical pipeline is unique in that it features mRNA-based vac-
cines, including cancer vaccines and prophylactic vaccines against 
infectious diseases. Our technology-agnostic innovation engine is 
driven by potential synergies between these technologies with the 
aim of enabling individualized treatment for cancer patients.

  Programs to combat global health burdens
Our infectious disease product strategy is rooted in our global social 
responsibility to address diseases with high or unmet medical need. We 
are committed to democratizing global access to innovative medicines. 

  Broadening the universe of patients benefiting from cancer 
immunotherapy
Our aim is to cover cancer at early, adjuvant and metastatic stages and 
to extend the utility of immunotherapy to patient populations that are 
currently not amenable or do not benefit from current immunotherapies. 

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  Improving the success rate through new combinations
We  develop  drug  candidates  that  are  precisely  tailored  to  the  re-
spective target. To augment the immune response and to counter-
act  resistance  mechanisms,  we  seek  to  combine  compounds  with 
non-overlapping and/or synergistic mechanisms of action, such as the 
combination of our FixVac immunotherapy CARVac with our innovative 
CAR-T therapy candidates. 

  Individualized approaches
The challenge in the treatment of cancer is its interindividual variability 
and heterogeneity, which increases the risk of recurrence or treatment 
failure. Addressing this biological reality is one of our fundamental prin-
ciples for the development of product candidates. For example, each 
of our mRNA cancer vaccine candidates incorporates multiple targets 
in order to account for this variability.

  Integrating AI into our pipeline and processes
Since  our  founding,  we  have  integrated  computer-aided  methods, 
data science, artificial intelligence (AI), and machine learning into our 
work. With the acquisition of InstaDeep, we aim to build world-leading 
capabilities in AI-driven drug discovery and development of next-gen-
eration immunotherapies and vaccines to address diseases with high 
unmet medical need. The objective is to enable high-throughput de-
sign and testing of novel drug candidates at scale. 

66

1.4 Commercialization

Our COVID-19 vaccine is based on our proprietary mRNA technology. The 
COVID-19 vaccine development program was launched in late January 
2020 in response to the COVID-19 pandemic. Under this program, two 
strategic collaborations with major pharmaceutical companies, Pfizer and 
Fosun Pharmaceutical Industrial Development Co. Ltd., Shanghai, China 
(Fosun Pharma), were completed and led to the first marketing authoriza-
tions of our vaccine in December 2020.

Under our collaboration with Pfizer, we are the marketing authorization 
holder in the United States, the European Union, the United Kingdom, 
Canada and other countries, and holder of emergency use authorizations, 
or EUAs, or equivalents in the United States (jointly with Pfizer) and other 
countries for the COVID-19 vaccine program. Pfizer has marketing and 
distribution rights worldwide with the exception of China, Germany and 
Turkey.  Fosun  Pharma  has  marketing  and  distribution  rights  in  China, 
Hong Kong special administrative region, or SAR, Macau SAR and the 
region of Taiwan. We have the marketing and distribution rights for the 
COVID-19 vaccine, known as Comirnaty, in Germany and Turkey.

In 2023, we and Pfizer continued our global COVID-19 vaccine leadership 
with our Omicron XBB.1.5-adapted monovalent COVID-19 vaccine. Since 
the beginning of the pandemic, we have developed and commercialized 
four COVID-19 vaccine products: the original COVID-19 vaccine, two vari-
ant-adapted bivalent vaccines (Original/Omicron BA.1 and Original/Omi-
cron BA.4-5-adapted bivalent vaccines) and the Omicron XBB.1.5-adapt-
ed monovalent COVID-19 vaccine.

As part of our and Pfizer’s two billion COVID-19 vaccine doses pledge 
to support equitable access to medicines for low- and middle-income 
countries (LMICs), we and Pfizer have delivered a total of around 1.8 billion 
doses of Comirnaty to LMICs in line with demand.

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We believe that we and our partner Pfizer are well positioned to main-
tain  our  leadership  role  in  the  development  and  commercialization  of 
COVID-19 vaccines.

1.5 Research and Development

Pipeline of Clinical Product Candidates
Our diversified portfolio consists of product candidates from different 
drug classes focused on the treatment of cancer and infectious diseases. 
There are currently 22 product candidates in oncology and seven product 
candidates in infectious diseases in clinical development.

In 2023, we initiated seven global clinical trials in oncology, including two 
Phase 3 trials (BNT323/DB-1303 and BNT316/ONC-392, gotistobart), 
three Phase 2 trials (BNT116, BNT311/GEN1046 and BNT122) and one 
Phase 1/2 trial (BNT324/DB-1311). In 2023, we brought several product 
candidates into mid- and late stage development, namely Phase 2 and 
3 clinical trials, including antibody drug conjugates (ADCs) and mRNA 
vaccines. In 2023, we expanded our technology base to include ADCs by 
initiating new collaborations with DualityBio and MediLink Therapeutics 
because we believe that this technology has the potential to supplement 
or replace highly toxic chemotherapy regimens as a new combination 
backbone of cancer treatment. Our growing pipeline now includes ADCs 
directed against four distinct targets and is of interest for a broad range 
of cancer types. Beyond ADCs, our collaborations with OncoC4 and Bio-
theus complement our pipeline with mid to late-stage clinical programs 
and have augmented our oncology pipeline.

We published clinical data for the following programs:

  Autogene cevumeran/BNT122, our individualized cancer vaccine 
program (iNeST) in collaboration with Genentech for patients with 
pancreatic ductal adenocarcinoma (PDAC) as an adjuvant therapy: 
Results from an investigator-initiated Phase 1 trial show that autogene 
cevumeran in combination with atezolizumab and mFOLFIRINOX in-
duces significant T-cell response in patients with surgically resected 
pancreatic ductal adenocarcinoma (PDAC) that correlates with de-
layed recurrence. 

  BNT116, our FixVac program for patients with non-small cell lung 
cancer (NSCLC): BNT116 was generally well tolerated and had a man-
ageable safety profile as monotherapy and in combination with cemi-
plimab. In heavily pretreated NSCLC patients, early clinical activity was 
observed with treatment with BNT116 with the addition of cemiplimab 
from cycle 3 onward.

  BNT211, our most advanced cell therapy program, which is being 
investigated alone and in combination with a CLDN6-encoding CAR-T 
cell amplifying mRNA vaccine (“CARVac”) in patients with germ cell tu-
mors and other solid tumors: The Phase 1/2 trial is evaluating the safety 
and efficacy of BNT211 in patients with CLDN6-positive relapsed or 
refractory advanced solid tumors. The data showed encouraging signs 
of clinical activity and improved persistence of cancer-specific CAR-T 
cells in combination with CARVac.

  BNT221, an autologous, fully personalized, polyspecific T-cell ther-
apy candidate directed against individual neoantigens in patients with 
metastatic melanoma: The first monotherapy data from the dose es-
calation phase of the Phase 1 trial demonstrate a manageable toler-
ability profile and signs of clinical activity in patients with pretreated 
advanced or metastatic melanoma.

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  BNT316/ONC-392 (gotistobart), an anti-CTLA-4 monoclonal anti-
body candidate in development in collaboration with OncoC4 Inc. for 
patients with metastatic NSCLC: The results show encouraging antitu-
mor activity for BNT316/ONC-392 as monotherapy in patients with im-
munotherapy (“IO”)-resistant NSCLC and a manageable safety profile.

  BNT323/DB-1303,  an  ADC  candidate  directed  against  HER2  in 
development  in  collaboration  with  DualityBio  and  being  evaluated 
in  patients  with  metastatic  breast  cancer  and  endometrial  cancer: 
BNT323/DB-1303 was well tolerated by patients with HR+/HER2-low 
breast cancer. Preliminary antitumor activity was observed in heavily 
pretreated patients with breast cancer. A manageable safety profile 
and encouraging antitumor activity was also observed in patients with 
endometrial cancer.

  BNT325/DB-1305, an ADC candidate directed against TROP2 in 
development in collaboration with DualityBio: A manageable safety 
profile and encouraging antitumor activity in patients with metastatic 
NSCLC were observed.

In infectious diseases,  we  started  three Phase  1  clinical trials for pro-
phylactic vaccine candidates based on our mRNA technology platform. 
These include candidates against malaria (proprietary program), tubercu-
losis (in collaboration with the Bill & Melinda Gates Foundation) and mpox 
(in partnership with CEPI).

Collaborations
In addition to the strategic collaborations with Pfizer and Fosun Phar-
ma entered into as part of the COVID-19 vaccine development program 
during the 2020 financial year, as well as the ongoing academic collab-
oration with the University Hospital Mainz and Translational Oncology at 
the University Medical Center of Johannes Gutenberg-Universität Mainz 
gemeinnützige GmbH (TRON), we have further developed the following 
collaborations with pharmaceutical and technology companies. 

  Genentech:  development  of  individualized  neo-epitope-specific 
mRNA immunotherapies for the treatment of various cancers within 
our iNeST platform. 

  Pfizer:  development  of  an  mRNA-based  influenza  vaccine  and  a 
combined mRNA-based influenza and COVID-19 vaccine as well as an 
mRNA-based herpes zoster virus vaccine. 

  Genmab: development of novel monospecific and bispecific check-
point immunomodulators. 

In 2023, we entered into multiple complementary agreements and collab-
orations, including:

  The completion of the acquisition of our long-time strategic col-
laboration partner InstaDeep Ltd., or InstaDeep, which enables us to 
leverage AI and ML technologies across our therapeutic platforms and 
operations. With our acquisition of InstaDeep, we have added indus-
try-leading AI and ML capabilities and approximately 290 profession-
als to our organization.

  An exclusive worldwide license agreement with OncoC4 for the joint 
development and commercialization of BNT316/ONC-392 (gotistob-
art), an anti-CTLA-4 monoclonal antibody as monotherapy or combi-
nation therapy in various cancer indications. As part of the agreement, 
we will hold the exclusive worldwide commercialization rights with 
participation of OncoC4 in certain markets.

  Exclusive license and collaboration agreements with DualityBio for 
the development, manufacture and global commercialization of three 
ADC candidates, BNT323/DB-1303 as well as BNT324/DB-1311 and 
BNT325/DB-1305, excluding Mainland China, Hong Kong Special Ad-
ministrative Region, and Macau Special Administrative Region.

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  A multi-year strategic partnership with the State of Victoria in Aus-
tralia  to  strengthen  the  local  mRNA  ecosystem  and  facilitate  inno-
vations deriving from it. As part of this partnership, BioNTech plans 
to build and operate a state-of-the-art mRNA manufacturing facility 
tailored to the needs of the local mRNA ecosystem and will set up an 
mRNA Innovation Center in Melbourne where the Company will lever-
age its expertise to support the development of the mRNA ecosystem 
in the State of Victoria.

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  A strategic research collaboration and worldwide license agree-
ment with MediLink Therapeutics (Suzhou) Co., or MediLink, for the 
development of a next-generation ADC, BNT326/YL202, against Hu-
man Epidermal Growth Factor Receptor 3 (HER3). Under the terms of 
the agreement, MediLink will grant BioNTech exclusive global rights, 
excluding Mainland China, Hong Kong Special Administrative Region, 
and Macau Special Administrative Region.

  A strategic research collaboration, option and worldwide license 
agreement with Biotheus Inc. (Biotheus) granting us worldwide, ex-
clusive options to a preclinical-stage bispecific antibody and a clini-
cal-stage monoclonal antibody for cancer therapy, BNT327/PM8002. 
We hold the rights to develop, manufacture and potentially commer-
cialize BNT327/PM8002, a bispecific antibody candidate targeting 
PD-L1 and VEGF-A, globally except in Greater China, where Biotheus 
retains the rights to BNT327/PM8002.

  A strategic partnership with CEPI to advance mRNA-based vaccine 
candidates  with  the  development  of  BNT166  for  the  prevention  of 
mpox.

  A strategic partnership with the Government of the United Kingdom 
(“UK”) with the aim to provide personalized mRNA cancer immuno-
therapies for up to 10,000 patients by 2030, either in clinical trials or as 
authorized treatments. We are also planning to invest in an R&D hub in 
Cambridge, United Kingdom.

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2 ECONOMIC REPORT

2.1 Macroeconomic and Sector-Specific Conditions

The  German  economy  declined  in  2023.  Inflation-adjusted  gross  do-
mestic product was 0.3%(1) lower than in the previous year. The energy 
crisis and geopolitical tensions spawned uncertainty and weighed on the 
economy. 

According to IMF experts, however, the global economy will have grown 
by 3.1% in 2023.(2)

Adjusted for inflation, the German pharmaceutical industry expects reve-
nues to fall by 2.9% in 2023(3) and production to be 1.4(3) lower. The reason 
cited is vaccination fatigue among the population and thus a fall in demand 
for vaccines. In 2022, revenues rose by 6.5%(4) on the back of high de-
mand for COVID-19 vaccines and production was up by 3.6%.(4)

In January 2023, the WHO’s expert panel stated that the COVID-19 pan-
demic remained a public health emergency of international concern, but 
this status was finally lifted in May.(5) Since June 2023, the COVID-19 vacci-
nation has been included in the general recommendations of the Standing 
Committee on Vaccination (STIKO) of the Robert Koch Institute.(6) These 
include the recommendation of baseline immunity for people without un-
derlying diseases between the ages of 18 and 59 and an annual booster 
vaccination for risk groups.

With the development and advancement of the COVID-19 vaccine against 
diverse COVID-19 variants, as well as an early warning system designed to 
detect SARS-CoV2 risk variants more quickly, we are working with other 
companies, research institutes and governments to continue to contrib-
ute to the worldwide effort to protect against COVID-19. Our goal remains 
to make the vaccine available to a broad population worldwide after the 
transition of the pandemic to an endemic phase. 

Therapeutics in Immunotherapy
The global market for mRNA therapeutics was estimated to be worth 
$45 billion(7) in 2023 and, according to a forecast by Precedence Re-
search, will expand at a compound annual growth rate of 13%(7) to around 
$138 billion(7) by 2032. Currently, mRNA vaccines are only approved for 
vaccination against COVID-19, yet there are many more under develop-
ment, e.g. to combat cancer.(8)

Marketing authorization, pricing, and reimbursement are highly regulated 
in healthcare. On the one hand, the strategy pursued by governments is to 
provide patients with highly effective and safe medicines in a timely man-
ner. On the other hand, cost pressure on global healthcare systems has 
been increasing for years. Therefore, drug manufacturers not only need 
to demonstrate the efficacy and safety of their products to gain approval, 
but also need to demonstrate the cost-effectiveness of their new drug 
against the respective standard of care to gain reimbursability. The rapid 
development of the COVID-19 vaccine, based on BioNTech’s proprietary 
mRNA technology, has demonstrated the potential of immunotherapies. 
The rapid, efficient and safe development was driven by BioNTech’s de-
cades of expertise in the research and development of mRNA-based 
vaccines. BioNTech’s mRNA vaccine technology allows for faster devel-
opment as well as shorter production cycles than would be possible with 
more traditional methods of vaccine production. This is critical in bringing 
a COVID-19 vaccine to market and meeting urgent medical needs. 

(1)  Source: https://www.destatis.de/EN/Themes/Economy/National-Accounts-Domestic-Product/Tables/

(4)  Source: https://www.aerzteblatt.de

gdp-bubbles.html

(5)  Source: https://www.tagesschau.de/ausland/europa/coronapandemie-who-gesundheitsnotstand-100.html

(2)  Source: https://www.imf.org/en/Publications/WEO/Issues/2024/01/30/ 

(6)  Source: https://www.kbv.de/html/1150_63927.php

world-economic-outlook-update-january-2024

(7)  Source: https://www.precedenceresearch.com/mrna-therapeutics-market

(3)  Source: https://www.pharmazeutische-zeitung.de/pharmabranche-erwartet-weniger-umsatz

(8)  Source: https://www.vfa.de/de/arzneimittel-forschung

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1  MAGAZINE 

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  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

2.2 Business Development Compared to the Forecast

The  following  table  compares  the  forecast  and  actual  figures  of  the  
BioNTech Group for the 2023 financial year:

Commercial COVID-19 vaccine 
revenues

Research and development 
expenses

Sales, general and administrative 
expenses

Investments in property, plant and 
equipment and intangible assets

Annual effective tax rate of the 
BioNTech Group

Forecast for the  
2023 financial year  
(published in Q4 2022  
earnings presentation)

Revised forecast for the  
2023 financial year  
(published in the Q2 2023  
earnings presentation)

Revised forecast for the  
2023 financial year  
(published in the Q3 2023  
earnings presentation)

Results for the  
2023 financial year

~ €5 billion

~ €5 billion

~ €4 billion

€3776.2 million

€2.4 billion to €2.6 billion

€2.0 billion to €2.2 billion

€1.8 billion to €2.0 billion

€1783.1 million

€650 million to €750 million

€600 million to €700 million

€600 million to €650 million

€557.7 million

€500 million to €600 million

€350 million to €450 million

€200 million to €300 million

€275.5 million

~ 27%

~ 21%

~ 21%

21.6%

A total of €3.8 billion in commercial COVID-19 vaccine revenues was gen-
erated in the 2023 financial year. This was around €1.2 billion below the 
initial forecast. The shortfall is attributable to lower proprietary COVID-19 
revenues due to weaker demand and a lower gross profit share from sales 
by our collaboration partner Pfizer, which was negatively impacted by 
write-downs of the partner’s inventories, among other things. 

The research and development expenses anticipated for the 2023 fi-
nancial year were around €700.0 million below the initial forecast range 
at €1.8 billion. This effect was due to the postponement of clinical trials 
as well as efforts to carefully review our cost base in the context of a de-
clining COVID-19 business with the aim of optimizing costs and forging 
partnerships to alleviate the financial burden. 

Initially,  we  expected  sales,  general  and  administrative  expenses  in 
the range of €600 million to €750 million for the 2023 financial year. At 
€557.7 million, the actual costs for the internal administrative and coordi-
native functions associated with the expansion of research and develop-
ment, such as finance, human resources, or business development, were 
around €100.0 million below the forecast costs. Altogether, we success-
fully reduced our sales, general and administrative expenses by actively 
managing our variable costs. We have optimized our corporate strategy to 
ensure that we use our resources effectively and efficiently and focus on 
the key areas. By systematically deprioritizing and postponing projects, 
we concentrated on our core initiatives and thus drove forward our suc-
cess. We also reigned in our expenditure by reducing external costs and 
consultancy to ensure our financial stability. In addition, fees for external 
counsel in connection with our legal disputes were reclassified from gen-
eral and administrative expenses to other operating expenses.

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  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Operating  investments  in  property,  plant  and  equipment  came  to 
€275.5 million in the past financial year. The expenditures for the expan-
sion and improvement of our research and development and manufac-
turing facilities and investments in IT infrastructure were thus around 
50% below the lower end of the range that was originally forecast. This 
was mainly attributable to delays in and halted construction projects as 
have been prevalent in the entire construction sector due to global supply 
problems.  Furthermore,  planned  investments  were  postponed  due  to 
short-term changes in priorities. 

Our effective tax rate in the 2023 financial year was 21.6%, 5.4 percent-
age points lower that the originally forecast rate. A reorganization of the 
intellectual property rights within the Group became effective as of June 
30, 2023 and July 1, 2023, which also led to tax effects. As a result, the 
effective tax rate fell in 2023.

2.3  Net Assets, Financial Position and Operating Results of 

the Group

2.3.1 Operating Results

Revenues
Our revenues mainly include commercial COVID-19 vaccine revenues 
in addition to research and development revenues from collaborations. 
Revenues from contracts with customers decreased by €13,491.6 million 
from €17,310.6 million during the 2022 financial year to €3,819.0 million 
during the 2023 financial year, as demand for our COVID-19 vaccine de-
clined compared to the previous year and the strong revenue figures from 
the 2022 financial year could therefore again not be achieved. In addition, 
the shared write-downs of our collaboration partner Pfizer’s inventories 
significantly reduced our gross profit share and hence our revenues for 
the year ended December 31, 2023. 

Accordingly, commercial revenues from the sale of our COVID-19 vaccine 
decreased by €13,369.0 million from €17,145.2 million during the 2022 
financial year to €3,776.2 million during the 2023 financial year.

Sales to collaboration partners represent sales of products manufac-
tured by us and transferred to partners. Whenever responsibilities in the 
manufacturing and supply process of the COVID-19 vaccine shift and the 
COVID-19 vaccine is transferred, the vaccine is sold from one partner to 
the other. Revenues from our collaboration partner Pfizer are significantly 
influenced by amounts due to write-downs of inventories as well as costs 
related to contracts with contract manufacturing organizations, or CMOs, 
included therein. Those costs represent accrued manufacturing vari-
ances compared to the original manufacturing costs and are shared with 
our partner under the collaboration agreement. These manufacturing 
variances are recognized as transfer price adjustments once identified. 
The regular reassessment of these manufacturing variances may result 
in adjustments to the respective prior-period revenues. The associated 
effects in the 2023 financial year amounted to €74.5 million (previous 
year: €850.0 million). During the 2023 financial year, revenues from selling 
products manufactured by us to collaboration partners decreased by a 
total of €949.0 million from €1,224.3 million during the 2022 financial year 
to €275.3 million.

Revenues from direct COVID-19 vaccine sales in our territories, Germany 
and Turkey, fell by €2,711.1 million from €3,184.7 million to €473.6 million 
during the 2023 financial year, compared to the previous year. The share 
of gross profit received by Pfizer as a collaboration partner based on our 
sales is recognized as cost of sales.

Based on COVID-19 vaccine sales in the collaboration partners’ territo-
ries, we are eligible to receive a share of their gross profit. This income is 
presented as a net figure in the statements of profit or loss and is recog-
nized as collaboration revenue during the commercial phase, together 
with sales milestones. Manufacturing cost variances either reflected as 

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1  MAGAZINE 

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  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

transfer price adjustments as described above or resulting from costs 
highly probable to be incurred by the partner were taken into account 
when determining the gross profit. Compared to the previous year, reve-
nues in this context decreased by €9,708.9 million from €12,736.2 million 
to €3,027.3 million during the 2023 financial year. 

Research and development revenues from collaborations decreased 
by €112.5 million from €116.0 million during the 2022 financial year to 
€3.5 million during the 2023 financial year. The decline was mainly at-
tributable to one-time effects in connection with Pfizer (influenza) and 
Sanofi S.A. (intratumoral mRNA-based therapies) in the previous year.

Cost of Sales
From the year ended December 31, 2022 to the year ended December 31, 
2023, cost of sales decreased by €2,395.2 million from €2,995.0 million to 
€599.8 million, mainly due to recognizing lower costs from our decreased 
COVID-19 vaccine sales, which included Pfizer’s share of our gross profit 
based on our sales. Our cost of sales contains inventory write-offs and 
expenses for production capacities derived from contracts with CMOs 
that became redundant. The effects were driven by reducing production 
capacities as well as further fostering the global production network with 
our collaboration partners during the year ended December 31, 2023. 

Research and Development Expenses

(in millions €)

Research and development expenses(1)

COVID-19

Non-COVID-19

(1)  Breakdown according to internal cost allocation rules.

From the year ended December 31, 2022 to the year ended December 31, 
2023, research and development expenses increased by €246.1 million 
from €1,537.0 million to €1,783.1 million, mainly influenced by progressing 
clinical studies for pipeline candidates as well as by our newly acquired 

Years ended December 31,

Change

2023

1,783.1

313.0

1,470.1

2022

1,537.0

550.0

987.0

€

246.1

(237.0)

483.1

%

16.0

(43.1)

48.9

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

product candidates and the development of variant-adapted COVID-19 
vaccines. The increase was further driven by an increase in wages, ben-
efits and social security expenses resulting from a significant increase in 
headcount.

2023 but were not designated as hedging instruments. Gains from foreign 
exchange forward contracts at fair value through profit or loss amounted 
to €67.6 million during the 2023 financial year compared to losses of 
€385.5 million in the previous year. 

Sales and Marketing Expenses
From  the  year  ended  December  31,  2022  to  the  year  ended  Decem-
ber 31, 2023, sales and marketing expenses increased by €3.2 million 
from €59.5 million to €62.7 million, mainly due to increased expenses for 
setup and enhancement of the commercial IT platform and an increase in 
wages, benefits and social security expenses resulting from an increase 
in headcount.

General and Administrative Expenses
From the year ended December 31, 2022 to the year ended Decem-
ber 31, 2023, general and administrative expenses adjusted for external 
legal fees in connection with certain legal disputes increased by €13.3 mil-
lion from €481.7 million to €495.0 million, mainly due to increased expens-
es for purchased IT services as well as an increase in wages, benefits and 
social security expenses resulting mainly from an increase in headcount. 

Other Operating Result
From the year ended December 31, 2022 to the year ended December 31, 
2023, the other operating result decreased by €593.3 million from posi-
tive €405.3 million to a negative result of €188.0 million. 

During the year ended December 31, 2023, the other operating result 
reflected a negative effect from recognizing foreign exchange differences 
arising on operating items (expenses of €252.0 million during the 2023 fi-
nancial year compared to gains of €727.4 million in the previous year). The 
decrease reflects the change in foreign exchange rates and is related to 
our U.S. dollar denominated trade receivables which were mainly incurred 
under our COVID-19 collaboration with Pfizer, U.S. dollar denominated 
trade payables as well as U.S. dollar denominated other financial liabili-
ties which mainly relate to obligations incurred from our license agree-
ments. To manage our transaction exposures, foreign currency forward 
contracts were entered into again during the year ended December 31, 

Finance Result
During the year ended December 31, 2023, the finance result increased 
compared to the year ended December 31, 2022 by €184.3 million from 
€311.4 million to €495.7 million.

During  the  year  ended  December  31,  2023,  the  finance  income  of 
€519.6 million was mainly due to interest income earned on financial se-
curities and bank deposits as well as fair value adjustments in relation to 
money market funds. During the year ended December 31, 2022, fair value 
measurement adjustments of the derivative embedded within our con-
vertible note had a significant impact on our finance result. 

Income Taxes
Our tax expenses decreased by €3,263.9 million from €3,519.7 million in 
the previous year to €255.8 million in the 2023 financial year. Income tax-
es comprise current taxes of €243.1 million (previous year: €3,629.6 mil-
lion) and deferred tax expenses of €12.7 million (previous year: deferred 
tax income of €109.9 million). Current income taxes include corporate 
income taxes and trade taxes of our German income tax group and are 
based on the calculated taxable income. Taxable income for 2023 is also 
net of deductible personnel expenses from our Employee Stock Owner-
ship Plans. Due to the decision by the Supervisory Board on the settle-
ment mechanism for the option rights at the end of September 2022, tax 
savings came to €19.8 million as of December 31, 2023, which are recog-
nized directly in equity as the tax-deductible amount exceeds the amount 
of the related cumulative share-based payment expense. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

In 2023, deferred tax assets are only recognized where the recognition 
criteria of IAS 12 are met as of December 31, 2023. Unrecognized deferred 
tax assets are re-assessed at each reporting date and are recognized to 
the extent that the recognition criteria of IAS 12 are met. The amount of 
deductible temporary differences, unused tax losses, and unused tax 
credits for which no deferred tax asset is recognized in the statement of 
financial position as of December 31, 2023 is €531.5 million. As of Decem-
ber 31, 2023, we recognize deferred tax assets on the losses of our U.S. 
tax group and other companies outside Germany. A reorganization of the 
intellectual property rights within the Group became effective as of June 
30, 2023 and July 1, 2023, which also led to deferred tax effects in Germa-
ny, Austria and the U.S. 

Annual Result
During the 2023 financial year, a profit of €930.3 million (previous year: 
€9,434.4 million) was generated. 

 2.3.2 Financial Position

The objective of financial management is to safeguard capital and to pro-
vide liquidity for the growth of the companies. The proceeds from com-
mercial sales of our COVID-19 vaccine have become our most important 
source of liquidity and resulted in a significant increase in cash and cash 
equivalents in the 2023 financial year. Scenario and cash flow planning 
are used to determine liquidity needs. 

Capital Structure
As of December 31, 2023, our share capital comprised 248,552,200 vot-
ing bearer shares, of which 10,826,465 were held as treasury shares. The 
par value of our shares is €1.00 and each confers one voting right at the 
Annual General Meeting. The financing of ongoing clinical trials, as well as 
the development, build-up of production capacity and commercialization 
of new formulations were primarily funded from cash flow from operating 
activities. 

In March 2022, our Management Board and Supervisory Board autho-
rized the 2022 share repurchase program of ADSs, pursuant to which 
ADSs with a value of up to $1.5 billion per ordinary share could be repur-
chased within a two-year period, commencing on May 2, 2022. In 2022, 
the first tranche of our 2022 share repurchase program of ADSs, with a 
value of up to $1.0 billion, concluded on October 10, 2022. The second 

tranche with a value of up to $0.5 billion commenced on December 7, 
2022 and concluded on March 17, 2023. In March 2023, our Management 
Board and Supervisory Board authorized the 2023 share repurchase 
program, under which ADSs with a value of up to $0.5 billion could be pur-
chased. It started on June 2, 2023 and concluded on September 18, 2023. 
During the year ended December 31, 2023, 6,868,136 ADSs were repur-
chased at an average price of $116.78 (€107.53), for total consideration of 
$802.1 million (€738.5 million).

Investments
During the 2023 financial year, investments were made in particular in 
property, plant and equipment in the amount of €249.4 million (previous 
year: €329.2 million). The investments were mainly made in connection 
with new buildings in Germany and investments in our BioNTainer. Invest-
ments in intangible assets amounted to €505.0 million during the 2023 
financial year (previous year: €34.2 million), primarily in connection with 
the acquisition of license and collaboration agreements with Duality Bi-
ologics Co. Ltd and OncoC4 Inc. In addition, €187.4 million was invested 
in intangible assets in connection with business acquisitions, mainly in 
the context of the acquisition of the new subsidiary InstaDeep Ltd. There 
were no business acquisitions in the previous year. 

Depreciation of property, plant and equipment amounted to €97.7 million 
during the 2023 financial year (previous year: €42.4 million). Amortization 
of intangible assets amounted to €40.5 million (previous year: €22.0 mil-
lion). 

For investing activities, we spent a total of €6,954.5 million during the 
2023 financial year (previous year: €35.3 million), primarily for first-time 
investments in bonds in the amount of €7,128.4 million.

Liquidity
As of December 31, 2023, our cash and cash equivalents amounted to 
€11,663.7 million compared to €13,875.1 million as of December 31, 2022 
and security investments to €5,989.7 million (previous year: nil), i.e. a total 
of €17,653.4 million. Primarily, the overall increase in cash inflow during the 
2023 financial year is due to payments received from commercial sales 
of our COVID-19 vaccine and our share of gross profit from commercial 
sales of the COVID-19 vaccine by our partner Pfizer included therein. The 
contractual settlement of the gross profit share has a temporal offset of 
more than one calendar quarter. In addition, Pfizer’s subsidiaries outside 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

the United States have a different financial quarter. We receive a large por-
tion of these payments via our partner Pfizer in U.S. dollars, which exposes 
us to significant concentration and currency risks. Operating activities, 
which mainly comprise the share of gross profit received, as well as pay-
ments in connection with research and development activities, generated 
a cash flow from operating activities of €5,371.4 million (previous year: 
cash flow of €13,577.4 million). 

Equity
Compared to December 31, 2022, equity increased by €190.3 million from 
€20,055.6 million to €20,245.9 million as of December 31, 2023. The in-
crease mainly resulted from the profit during the 2023 financial year, part-
ly offset by effects from the share repurchase program of €738.5 million. 
The equity ratio increased by 1.8 percentage points to 88.0% (previous 
year: 86.2%).

Net cash used in financing activities for the year ended December 31, 
2023 was €778.6 million (previous year: €1,419.3 million). The main com-
ponent was the cash of €738.5 million used in connection with the share 
repurchase program.

2.3.3 Net Assets

As of December 31, 2023, total assets amounted to €23,006.3 million 
compared to €23,279.1 million as of December 31, 2022. The decrease 
was mainly due to lower receivables from Pfizer as a result of reduced 
COVID-19 vaccine sales, as well as the following developments: 

Current and Non-Current Assets
Compared  to  December  31,  2022,  non-current  assets  increased  by 
€2,121.9 million from €1,357.1 million to €3,479.0 million as of December 31, 
2023, due primarily to investments in non-current securities and intangi-
ble assets.

The €2,394.7 million decrease in current assets from €21,922.0 million 
as of December 31, 2022 to €19,527.3 million as of December 31, 2023 is 
mainly attributable to two contrasting effects: While total cash and cash 
equivalents and securities increased, receivables from our COVID-19 col-
laboration with Pfizer and receivables from our customers that we supply 
directly in our territory decreased due to lower demand at the end of the 
2023 financial year. 

Current and Non-Current Liabilities
Compared to December 31, 2022, liabilities decreased by €463.1 million 
from €3,223.5 million to €2,760.4 million as of December 31, 2023. The 
decrease was mainly attributable to the remittance of wage taxes and so-
cial security expenses in connection with the settlement of the Employee 
Stock Ownership Plans (ESOP 2018 and LTI-plus) and lower obligations 
incurred from our license agreements.

Off-Balance Sheet Commitments
The off-balance sheet commitments include the following:

(in millions €)

December 31, 2023 December 31, 2022

Commitments under purchase agreements 
for property, plant and equipment

Contractual obligations to acquire 
intangible assets

Total

154.4

1,721.1

1,875.5

105.2

—

105.2

Contractual obligations to acquire intangible assets exist in connection 
with in-licensing and research and development cooperations. We have 
entered into obligations to pay milestone payments once specific targets 
have been reached. Provided that all of the milestone events are achieved, 
we would be obligated to pay up to €1,721.1 million as of December 31, 
2023 (nil as of December 31, 2022) in connection with the acquisition of 
intangible assets. The amounts shown represent the maximum payments 
to be made, and it is unlikely that they will all fall due. The amounts and 
the dates of the actual payments may both vary considerably from those 

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  OF BioNTech SE

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  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

BioNTech | Annual Report 2023

77

stated in the table, since the achievement of the conditions for payment 
is possible but uncertain. Other financial obligations from possible future 
sales-based milestone and license payments were not included in the 
table above.

a relevant contribution to supporting the third United Nations Sustainable 
Development Goal (SDG 3): Ensure healthy lives and promote well-being 
for all at all ages. 

The expected maturities of payment obligations under purchase agree-
ments for property, plant and equipment and contractual obligations to 
acquire intangible assets are as follows:

(in millions €)

Less than 1 year

1 to 5 years More than 5 years

Commitments under 
purchase agreements 
for property, plant and 
equipment

Contractual obligations 
to acquire intangible 
assets

Total

152.5

1.9

—

BioNTech SE

249.4

401.9

954.9

956.8

516.8

516.8

2.4.  Key Performance Indicators of the Group and  

BioNTech SE

2.4.1  Non-Financial Key Performance Indicators of the Group and 

BioNTech SE

Innovation was classified as a material non-financial key performance 
indicator during the 2023 financial year and was used for internal man-
agement.

We are working on the development of innovative drugs for diseases with 
high or unmet medical need. We continue to build our pipeline, which has 
grown in recent years in line with the Company’s fundamental vision of 
harnessing the power of the immune system to fight cancer and other se-
rious diseases. BioNTech supports the United Nations Sustainable Devel-
opment Goals (SDGs). In this context, with our business model, we make 

Progress in research achievements and the advancement and expanded 
commercialization of our COVID-19 vaccine are key performance indica-
tors for our Company. We are working to clinically demonstrate the ben-
efit of additional treatment approaches, further develop additional prod-
uct candidates in studies with potential for approval, and continuously 
expand collaborations and manufacturing capabilities to offer innovative 
treatments to patients around the world. 

2.4.2 Financial Key Performance Indicators of the Group and  

The following financial key performance indicators are in the focus of our 
operational business development management. We use the measures 
based on current exchange rates (not currency adjusted) and take effects 
from potential M&A activities or collaborations into account where these 
have been published. 

Revenues
Total revenues mainly comprise expected commercial revenue, particu-
larly in connection with our COVID-19 business as well as other revenue 
sources. Revenues are heavily influenced by the volumes available under 
the collaboration and the agreed upon purchase quantities. As our rev-
enues represent our share of gross profits of the collaboration partners’ 
gross profit, they are also influenced by the incurring costs. For further 
information on the composition of commercial COVID-19 vaccine sales 
and the components contained therein, see the comments on sales under 
2.3.1 Operating Results. Our sales serve as a performance indicator of our 
commercial earning power. 

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  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Research and Development Expenses
Research and development expenses are an indicator of our future earn-
ings potential, as this is highly dependent on the development of the clin-
ical pipeline and the responsible management of the financial resources 
generated. This figure mainly includes expenses for the development of 
our clinical product candidates, early exploratory research and research 
and development overhead costs.

Sales, General and Administrative Expenses
These costs include sales and marketing costs as well as general and 
administrative costs. We use this measure to manage the costs associat-
ed with the expansion of the sales and marketing organization to ensure 
the necessary infrastructure and digital capacity for future market-ready 
products, as well as to manage the internal administrative and coordina-
tive functions associated with the expansion of research and develop-
ment, such as finance, human resources, or business development, with 
regard to the associated cost development. 

Investments in Property, Plant and Equipment and Intangible Assets
Capital expenditures for property, plant and equipment and intangible 
assets include expenditures for the acquisition of property, plant and 
equipment as well as expenditures for the acquisition of intangible assets 
and rights of use, unless they are made as part of mergers and acquisi-
tions (M&A). These mainly include expenditures for the expansion and 
improvement of our research and development and manufacturing facil-
ities and investments in a state-of-the-art IT infrastructure to support the 
Company in all digitization projects.

2.5  Overall Statement on the Business Development and 

Position of the Group and BioNTech SE

We are a global immunotherapy company pioneering the development 
of novel medicines against cancer, infectious diseases and other serious 
diseases. These activities still require high investments at this stage. In ad-
dition to financial metrics, we continue to measure our business success 
primarily by our research performance, and in particular by the achieve-
ment of the targets we have set. Together with collaboration partners, we 
have generated a robust and diversified oncology and infectious disease 
pipeline. There are currently 22 product candidates in oncology and sev-
en product candidates in infectious diseases in clinical development. In 
the 2023 financial year, we continuously advanced and diversified our 
pipeline, progressing in line with expectations and planning. Among other 
things, we expanded our access to a new technology – ADCs – in 2023. In 
addition, with the acquisition of our long-time strategic collaboration part-
ner InstaDeep, we have taken a further step in our strategy, aiming to build 
world-leading capabilities in AI-driven drug discovery and development of 
next-generation immunotherapies and vaccines to address diseases with 
high unmet medical need. We are well positioned to continue BioNTech’s 
successful development in what remains a challenging market environ-
ment in 2024.

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2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

3  MANAGEMENT REPORT OF 

BioNTech SE

3.2  Net Assets, Financial Position and Operating Results of 

BioNTech SE

3.2.1 Operating Results

3.1  Supplementary Notes According to the  

German Commercial Code (HGB)

BioNTech SE is the parent company of the BioNTech Group and is head-
quartered in Mainz, Germany. In addition, as of the end of the 2023 financial 
year, the BioNTech Group included 41 group companies. Key management 
functions for the Group, such as corporate strategy, risk management, 
investment management tasks, executive and financial management, as 
well as communication with important target groups of the Group, are the 
responsibility of the Management Board of BioNTech SE. With its operating 
activities, in particular in connection with the two collaboration agreements 
with Pfizer and Fosun Pharma, which were concluded by BioNTech SE in 
the context of the COVID-19 vaccine program, BioNTech SE generated the 
bulk of the Group’s revenues. 

BioNTech SE is not managed separately using its own key performance 
indicators,  as  the  Company  is  integrated  into  the  group  management 
system. The explanations given for the Group apply. The economic frame-
work conditions of BioNTech SE essentially correspond to those of the 
BioNTech Group and are described in detail in Section 2.

Years ended December 31,

(in millions €)

Revenues

Cost of sales

Gross profit

2023

3,270.1

(250.0)

3,020.1

Research and development expenses

(1,743.6)

Sales expenses

General and administrative expenses

Other operating income

Other operating expenses

Operating income

(29.4)

(535.1)

299.5

(315.6)

695.9

2022

12,514.5

(1,615.7)

10,898.8

(1,519.7)

(29.1)

(475.4)

1,041.3

(717.1)

9,198.8

Income from profit transfer

184.6

2,863.3

Income from other securities and loans 
classified as fixed financial assets

Other interest and similar income

Expenses from loss transfer

Interest and similar expenses

Profit before tax

Income taxes

Net income

29.7

366.7

(166.2)

(78.0)

1,032.7

(233.2)

799.5

—

51.8

(86.9)

(30.9)

11,996.1

(3,370.1)

8,626.0

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  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Revenues
Revenues decreased by €9,244.4 million from €12,514.5 million during 
the 2022 financial year to €3,270.1 million during the 2023 financial year. 
Commercial revenues decreased due to lower demand for our COVID-19 
vaccine and are largely attributable to revenue recognition under the col-
laboration agreement with Pfizer, to which BioNTech SE is a party. 

Cost of Sales
From  the  year  ended  December  31,  2022  to  the  year  ended  Decem-
ber 31, 2023, cost of sales decreased by €1,365.7 million from €1,615.7 mil-
lion to €250.0 million due to the decline in COVID-19 vaccine sales. Cost 
of sales primarily includes the share of our gross profit that Pfizer receives 
as a collaboration partner based on our sales. In addition, sales-related 
licensing costs for third-party intellectual property contribute to the cost 
of sales. 

Research and Development Expenses
From  the  year  ended  December  31,  2022  to  the  year  ended  Decem-
ber 31, 2023, research and development expenses increased by €223.9 
million from €1,519.7 million to €1,743.6 million, mainly due to progressing 
clinical studies for our pipeline candidates as well as our newly acquired 
product candidates and the development of variant-adapted COVID-19 
vaccines. The increase was further driven by an increase in wages, ben-
efits and social security expenses resulting from a significant increase in 
headcount. 

General and Administrative Expenses
From the year ended December 31, 2022 to the year ended December 31, 
2023, general and administrative expenses increased by €59.7 million 
from €475.4 million to €535.1 million, mainly due to the expenses from the 
remittance of wage taxes and social security expenses from the exercise 
of our share-based payments, increased expenses for purchased IT ser-
vices as well as an increase in wages, benefits and social security expens-
es resulting mainly from an increase in headcount.

Other Operating Result
From the year ended December 31, 2022 to the year ended December 
31, 2023, the other operating result decreased by €340.3 million from 
positive €324.2 million to a negative result of €16.1 million. This item mainly 
included foreign currency gains from the translation of our U.S. dollar 
denominated trade receivables, which mainly arose from our COVID-19 
collaboration with Pfizer. The offsetting effects mainly include expenses 
from foreign exchange forward contracts.

Finance Result
During the year ended December 31, 2023, the finance result, compris-
ing the effects of profit transfer and interest income and expenses, de-
creased by €2,460.5 million compared to the year ended December 31, 
2022 from €2,797.3 million to €336.8 million. The decrease resulted in 
particular from the decline in income from the profit transfer from affiliated 
companies (net profit transfer of €18.4 million; previous year: net profit 
transfer of €2,776.4 million). During the year ended December 31, 2023, 
the interest result included in the finance result improved by €297.5 million 
compared to the year ended December 31, 2022 from €20.9 million to 
€318.4 million, which is mainly due to interest income earned on securities. 

Income Taxes
Income taxes amounted to €233.2 million during the 2023 financial year 
(previous year: €3,370.1 million). Income taxes comprise current taxes 
of €233.2 million (previous year: €3,442.3 million) and no deferred tax 
expense or deferred tax income (previous year: deferred tax income of 
€72.3 million). The decrease in current taxes is due to a decline in revenue 
recognition related to our COVID-19 vaccine sales and includes corporate 
income taxes and trade taxes of our German income tax group and is 
based on calculated taxable income. Taxable income is also net of de-
ductible personnel expenses from our share-based payments programs. 
In the HGB, or German GAAP accounts, the Supervisory Board decision 
on the ESOP 2018 resulted in a present obligation to settle in cash with 
regard to the wage tax from the exercise of the share-based payments. 
Consequently, pursuant to German GAAP, the difference between the 
value of the wage tax payment and the fair value of the pro rata rights 
was recognized as an additional expense as of the grant date. Our share-
based payments programs resulted in aggregate actual tax savings of 

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  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Liquidity
As of December 31, 2023, our cash and cash equivalents amounted to 
€11,409.5 million compared to €13,798.0 million as of December 31, 2022, 
securities classified as fixed assets amounted to €1,326.4 million (previ-
ous year: nil) and other securities amounted to €4,662.6 million (previous 
year: nil), i.e. a total of €17,398.5 million. Primarily, the overall increase in 
cash inflow during the 2023 financial year is due to payments received 
from commercial sales of our COVID-19 vaccine and our share of gross 
profit from commercial sales of the COVID-19 vaccine by our partner 
Pfizer included therein. The contractual settlement of the gross profit 
share has a temporal offset of more than one calendar quarter. In addition, 
Pfizer’s subsidiaries outside the United States have a different financial 
quarter. We receive a large portion of these payments via our partner 
Pfizer in U.S. dollars, which exposes us to significant concentration and 
currency risks. Operating activities, which mainly include the share of 
gross profit received, as well as payments in connection with research 
and development activities, generated a cash flow from operating activi-
ties of €4,514.8 million (previous year: cash flow of €13,148.0 million). 

Net cash used in financing activities for the year ended December 31, 
2023 was €813.4 million (previous year: €552.9 million). The main com-
ponent was the cash of €738.5 million used in connection with the share 
repurchase program.

€11.9 million, which are recognized directly in equity as the tax-deductible 
amount exceeds the amount of the related cumulative share-based pay-
ment expense. 

Annual Result
During the 2023 financial year, net income of €799.5 million (previous 
year: €8,626.0 million) was reported.

 3.2.2 Financial Position

The objective of the financial management of BioNTech SE is essentially 
identical to that of the Group and involves providing liquidity for the growth 
of the group companies. 

Capital Structure
As  of  December  31,  2023,  our  share  capital  comprised  248,552,200 
voting bearer shares, of which 10,826,465 were held as treasury shares. 
The capital reserve decreased mainly in connection with the share repur-
chase program. 

Investments
Total investments of €2,598.1 million were made during the 2023 financial 
year (previous year: €703.5 million). The amount consisted of investments 
in property, plant and equipment amounting to €59.2 million (previous 
year: €75.7 million) and investments in intangible assets amounting to 
€667.2 million (previous year: €31.8 million) as well as investments in se-
curities classified as fixed assets and shares in affiliated companies and 
other loans amounting to €1,871.7 million (previous year: €596.0 million), 
primarily driven by the acquisition of InstaDeep and, to a lesser extent, 
financing activities for subsidiaries.

Depreciation of buildings, other equipment, furniture and fixtures amount-
ed to €21.4 million in 2023 (previous year: €14.4 million). Amortization of 
intangible assets amounted to €63.9 million (previous year: €12.0 million). 

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2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

3.2.3 Net Assets

(in millions €)

Assets

Fixed assets

Intangible assets

Property, plant and equipment

Financial assets

Total fixed assets

Current assets

Inventories

Receivables and other assets

Other securities

Cash on hand and at banks

Total current assets

Prepaid expenses

Total assets

December 31, 2023 December 31, 2022

(in millions €)

December 31, 2023 December 31, 2022

Equity and liabilities

Equity

71.9

99.9

Share capital

Capital reserve

1,279.7

Treasury shares

1,451.5

Retained earnings

Accumulated profit

0.7

Total equity

7,273.3

Provisions

—

Tax provisions

13,798.0

Other provisions

21,072.0

Total provisions

63.5

Liabilities

22,587.0

Trade payables

674.6

136.5

2,542.8

3,353.9

1.2

2,813.9

4,662.6

11,409.5

18,887.2

216.3

22,457.4

Liabilities to affiliated companies

Other liabilities

Total liabilities

Deferred income

248.6

695.6

(10.8)

9,845.1

9,361.0

20,139.5

525.1

571.7

1,096.8

254.2

485.8

93.4

833.4

387.7

Total equity and liabilities

22,457.4

248.6

1,295.4

(5.3)

9,445.4

8,961.2

19,945.3

606.1

923.3

1,529.4

57.2

389.6

651.6

1,098.4

13.9

22,587.0

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  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

As of December 31, 2023, total assets amounted to €22,457.40 million 
compared to €22,587.0 million as of December 31, 2022. A significant part 
of this balance comprises cash on hand and at banks stemming from our 
COVID-19 collaboration with Pfizer and the payments received under the 
profit and loss transfer agreements derived from the COVID-19 vaccine 
sales of our subsidiaries. The changes in our total assets are mainly due to 
the following developments:

Fixed Assets and Current Assets
Compared to December 31, 2022, fixed assets increased by €1,902.4 mil-
lion from €1,451.5 million to €3,353.9 million as of December 31, 2023. 
Besides additions in intangible assets, financial assets increased due to 
the investments in securities.

Compared  to  December  31,  2022,  current  assets  decreased  by 
€2,184.8 million from €21,072.0 million to €18,887.2 million as of Decem-
ber 31, 2023. The decline mainly resulted from the decrease in receiv-
ables from Pfizer as a result of lower demand for our COVID-19 vaccine. 

Equity
Compared to December 31, 2022, equity increased by €194.2 million, 
from €19,945.3 million to €20,139.5 million as of December 31, 2023. The 
increase resulted primarily from the net income generated during the 
2023 financial year. The equity ratio increased by 1.4 percentage points to 
89.7% (2022: 88.3%).

Provisions and Liabilities
Compared to December 31, 2022, provisions and liabilities decreased by 
€697.6 million from €2,627.8 million to €1,930.2 million as of December 31, 
2023, largely as a result of lower provisions for outstanding invoices and 
miscellaneous provisions as well as lower liabilities from wage taxes and 
social security expenses.

Off-Balance Sheet Commitments
Contingent liabilities relate to potential future events whose occurrence 
would give rise to an obligation. As of the reporting date, contingent lia-
bilities from guarantees amounted to €642.8 million. The risk of claims is 
considered to be low due to the central management of the subsidiaries, 
taking into account the Group’s good financial position.

Other  financial  obligations  include  the  following  rental  and  lease 
obligations:

(in millions €)

Less than 1 year

1 to 5 years More than 5 years

Rental agreements

8.5

28.1

7.2

Rental and lease agreements offer the benefit of optimizing liquidity. There 
are  no  identifiable  significant  risks.  The  aforementioned  transactions 
include expenses from rental agreements with ATHOS KG, Holzkirchen, 
Germany, or entities controlled by them.

There are also other financial obligations in connection with the purchase 
of property, plant and equipment and intangible assets: 

(in millions €)

Less than 1 year

1 to 5 years More than 5 years

Commitments under 
purchase agreements 
for property, plant and 
equipment

Contractual obligation to 
acquire intangible assets

Total

152.5

249.4

401.9

1.9

954.9

956.8

—

516.8

516.8

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  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The financial obligations in connection with the purchase of intangible as-
sets arise from the license and collaboration agreements concluded and 
the resulting obligations to make milestone payments to the collaboration 
partner as well as the contractual obligation under purchase agreements 
for property, plant and equipment. Provided that all contractually agreed 
milestones are reached, the Company would be obligated to pay up to 
€1,875.5 million as of December 31, 2023.

3.3 Forecast, Opportunity and Risk Report

The business development of BioNTech SE is essentially subject to the 
same risks and opportunities as the BioNTech Group, as BioNTech SE 
participates in the risks of the group companies via its investments. As 
a result of the central financial management of the BioNTech Group, all 
financing transactions are primarily conducted via BioNTech SE. As the 
parent company of the BioNTech Group, BioNTech SE is integrated into 
our Group-wide risk management.

3.4 Relationships with Affiliated Companies 

Final declaration of the Management Board of BioNTech SE on the re-
port on relationships with affiliated companies for the 2023 financial year 
(dependent company report pursuant to Section 312 para. 3 sentence 3 
AktG): 

“According to the circumstances known to us at the time when the legal 
transactions were carried out or the actions were taken, BioNTech SE 
received appropriate consideration for each legal transaction and was 
not disadvantaged. In the financial year, no actions were taken or omitted 
at the instigation of or in the interests of ATHOS KG or its affiliated compa-
nies in the period from January 1 to December 31, 2023.”

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  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

4  FORECAST, OPPORTUNITY  

AND RISK REPORT

4.1 Forecast

We as a company are part of the pharmaceutical and biotechnology in-
dustry, which stands out nationally and internationally for its innovative 
strength. The growth prospects for the industry are considered to be 
good, driven by its independence from economic cycles, global demo-
graphic change and medical and technological progress. Based on the 
Company’s proprietary mRNA technology, we succeeded in becoming 
the first company worldwide to develop a highly effective and safe vaccine 
against COVID-19 in compliance with scientific standards within one year 
and to then successfully market it globally. This demonstrates our ability 
to develop and commercialize medicines and therapies based on innova-
tive technologies that can add value for patients and society. 

We expect consolidated revenues of €2.5 billion to €3.1 billion for the 2024 
financial year.

The revenue forecast mainly comprises commercial revenues from our 
COVID-19 vaccine business and is based on various assumptions includ-
ing, but not limited to, the transition still expected in 2024 from a mar-
ket environment with purchase agreements between governments and 
vaccine manufacturers to commercial market orders and a regulatory 
recommendation to adapt the COVID-19 vaccines to the latest circulating 
variants or sublineages of SARS-CoV-2. Our estimated COVID-19 vaccine 
revenues reflect the deliveries anticipated under existing or promised 
supply agreements as well as expected sales from conventional commer-
cial orders. While we anticipate an increase in demand due to a vaccine 
adaptation, we expect fewer primary vaccinations and a lower percent-
age of booster vaccinations within the population as a whole. We expect 

that our revenues will be shaped by purchases of our COVID-19 vaccine in 
the second half of the year.

Revenue is heavily influenced by the volumes available under the collabo-
ration and the agreed upon purchase quantities, to which we have adjust-
ed our production capabilities accordingly. As our revenues represent our 
share of gross profits of the collaboration partners’ gross profit, they are 
also influenced by the incurring costs. 

We aim to generate long-term sustainable revenues from the COVID-19 
vaccine program and maintain our leadership role in the development and 
commercialization of COVID-19 vaccines. We have developed and mar-
keted four COVID-19 vaccine products since the start of the pandemic. 
Going forward, we intend to continue our work with Pfizer to create the 
conditions to flexibly adapt the vaccine to other potential future muta-
tions if necessary, to continually optimize the formulations and to make 
the product accessible to additional patient groups through indication 
extensions. 

As described above, the range of revenue we forecast depends on vari-
ous factors. Our revenue forecast is based on largely stable vaccination 
rates and can be influenced by a change in price levels, particularly in the 
more competitive U.S. market. The forecast factors in expected write-
downs recognized by our collaboration partner Pfizer. 

In addition to COVID-19 vaccine revenues, we plan to develop further 
revenue sources, such as from the framework agreement signed with the 
Federal Republic of Germany on pandemic preparedness including man-
ufacturing and supply of mRNA vaccines and, for example, revenues from 
external sales by our subsidiaries InstaDeep Ltd., JPT Peptide Technol-
ogies GmbH and BioNTech Individualized mRNA Manufacturing GmbH.

With the successful production and commercialization of our COVID-19 
vaccine, we have built up a wealth of expertise and a global network to 
develop,  produce  and  commercialize  products  worldwide.  Our  future 
earnings potential is highly dependent on the development of the clinical 
pipeline and the responsible use of the financial resources generated. We 
have generated a broad pipeline of product candidates across a range 

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  REPORT 

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  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

of technology platforms and, in addition, intend to reinvest the proceeds 
from the sale of our COVID-19 vaccine in our advanced clinical candidates 
and in the further expansion of our therapeutic platforms. During the 2024 
financial year, we expect to make significant progress in several clinical 
trials and present data updates for numerous development programs. In 
connection with building our product pipeline in oncology and infectious 
disease and expanding into new areas such as autoimmune diseases, 
regenerative  medicine  and  allergies,  we expect  our research and de-
velopment expenses to continue to increase. In this context, we expect 
expenses of €2.4 billion to €2.6 billion for the 2024 financial year. 

Costs are also expected to increase for the internal administrative and 
coordinative functions associated with the expansion of research and de-
velopment, such as finance, human resources, or business development. 
For the 2024 financial year, we expect sales, general and administrative 
expenses in the range of €700.0 million to €800.0 million. This forecast 
does not include expenses for external legal counsel in connection with 
certain legal disputes, as these are recognized in the other operating re-
sult. Nor does it include potential payments that may arise from the results 
of current or future legal disputes or related judgments or settlements.

Operating investments in property, plant and equipment and intangible 
assets will also increase. For the 2024 financial year, we expect operating 
investments in property, plant, equipment and intangible assets in the 
range of €400.0 million to €500.0 million. This includes expenditures for 
the expansion and improvement of our research and development and 
manufacturing facilities described above and further investments in IT 
infrastructure to support the Company in its bio-digital transformation and 
our focus as a data-driven enterprise. 

Based on the guidance for revenues and considering cost of sales, re-
search and development expenses and all other costs, we do not expect 
to turn a profit in 2024.

In 2023, we strengthened our technology platforms, our digital capabili-
ties, and our infrastructure through relevant investments, select strategic 
partnerships, licensing and acquisitions to bring long-term added value 
to patients, shareholders, and to society. In 2024, we intend to continue 
building our oncology pipeline towards our first oncology product launch 

in 2026 and to apply for ten further indication approvals by 2030. Longer 
term, we see potential applications for our technologies beyond oncology 
and infectious disease, including autoimmune diseases, inflammatory 
diseases,  cardiovascular  diseases,  neurodegenerative  diseases,  and 
regenerative medicines. 

4.2 Risk Report

4.2.1 Risk Governance Framework

Risk Management System
As a next-generation immunotherapy company, we are exposed to nu-
merous uncertainties and changes resulting, for example, from new re-
search approaches. These uncertainties can have a significant impact on 
the planned business performance. BioNTech is aware of the need to take 
risks in order to exploit opportunities that arise. Our risk management sys-
tem (RMS) describes the systematic approach to identifying, assessing, 
managing, mitigating and communicating risks. As part of our risk gov-
ernance framework, a functioning risk management system is a central 
element of value-based corporate governance and applies to all divisions, 
subsidiaries and locations throughout the Group. The risk management 
function belongs to the Business Planning & Analysis department and 
reports directly to the CFO.

Risk Management Process
Our Management Board and Supervisory Board jointly determine the risk 
strategy and risk appetite. Our company-wide risk management system 
covers strategic, operational, financial, legal, compliance and reputational 
risks. Our systems are constantly being reviewed and enhanced, and will, 
for instance, address environmental, climate and human rights aspects 
more systematically in the future. This also includes the requirements of 
double materiality in accordance with the EU Corporate Sustainability Re-
porting Directive (CSRD), whereby BioNTech will have to report on both 
the impact of the Company’s activities on people and the environment 
and the impact of sustainability aspects on the Company from the 2025 
financial year onwards.

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  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The regular risk cycle is completed once every six months. Our risk own-
ers and experts assess the risks and decide how to respond to them. 
Enterprise Risk Management regularly reports to the Management Board 
on the overall risk situation. Ad hoc risks are continuously identified, as-
sessed and, if necessary, reported directly to the Management Board. 

Risk Identification
At BioNTech, new risks are systematically identified and analyzed. Exist-
ing risks were re-assessed, and reviewed and refined with regard to their 
substance and assessment, and adjusted where necessary.

The individual risks are assigned to our risk owners, who are responsible 
for the management of these risks and who have the necessary compe-
tencies and level of responsibility to do so. The risk owners evaluate the 
individual risks quantitatively by determining the probability of occurrence 
and the estimated monetary impact. In addition, the risks are expanded 
to include the dimensions of “reputational damage” and “legal relevance” 
and assessed qualitatively.

The risk identification process is supported by a risk management tool, 
which catalogs risks within our risk universe. In order to capture the full 
range of possible outcomes, the risks are aggregated using a Monte Carlo 
simulation. A comparison of the resulting value-at-risk and our risk-bear-
ing capacity enables us to manage risks comprehensively. The risk-bear-
ing capacity plan refers to several metrics such as rating, our equity, EBIT 
and our cash and cash equivalents and compares them with the aggre-
gated overall risk in the short, medium and long term.

Risk Assessment and Management
Risks are assessed in financial terms according to “probability of occur-
rence” and “damage potential”. Probability of occurrence is rated on a 
scale ranging from “very unlikely” to “very likely”, while damage poten-
tial is rated on a scale from “low” to “critical”. Risks arise depending on 
the combined magnitude of the two factors and are classified as “high”, 
 “medium” or “low”. The order in which the risks are presented within the 
three  categories reflects the current assessment of the relative mag-
nitude of risk for us and therefore provides an indication of the current 
significance of these risks for us.

However, risks with a currently low estimated damage potential may have 
a greater impact in the future than currently assessed and are therefore 
continuously monitored by Central Risk Management. 

We monitor identified risks continuously and respond to them in different 
ways. For each risk, we make an individual decision as to whether or not to 
accept the risk. Alternatively, we consider, for example, whether we can 
cover (or transfer) the risk by insurance or mitigate it by other means. 

Risk Reporting
The aim is to identify, monitor and manage our risks at an early stage. 
Risks and their impact on the Company are presented transparently in 
order to enable effective management of these risks. We use internal and 
external sources of information for this purpose.

Central Risk Management prepares an overall risk report for the Man-
agement Board twice a year. The Risk Committee comments on the risk 
report and validates the greatest risks, recommends responses and iden-
tifies interdependencies between the risks. The Management Board then 
informs the Audit Committee. If unexpectedly high risks arise – in addition 
to the regular reporting of significant risks – these are reported directly to 
the Management Board. The Audit Committee of our Supervisory Board 
examines the effectiveness and adequacy of the risk management sys-
tem and also calls on the Internal Audit department for this purpose. 

Risk Culture
BioNTech practices and promotes an open risk culture. All employees can 
approach their manager or Enterprise Risk Management directly or re-
port new risks (anonymously) via a reporting portal. Training courses are 
offered every six months for all risk owners and experts, and the training 
documents are available to all employees via the intranet. The information 
collected can then be forwarded directly to the relevant risk owner or 
discussed in workshops. Regular news articles are addressed to all em-
ployees and underline the open risk culture.

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  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Three Lines Model
Our objective is to anticipate potential developments at an early stage and 
to systematically identify, assess and manage any resulting risks. In order 
to systematically manage risks, the governance structure of BioNTech 
is based around the three lines model. From an operational perspective, 
activities in the first line are aimed at compliance with the requirements 
defined in the second line and application of controls as part of day-to-day 
operations. The second line comprises risk management as well as our in-
ternal control system (see 4.2.3) and our compliance and ethics program 
(see 5.4 Integrity and Ethics). This line provides systems and expertise to 
systematically detect risks, defines the control framework and sets pol-
icies. Internal Audit, which was newly implemented in the 2022 financial 
year, is the third line (see 4.2.3). 

4.2.2 Risks

Risks with the Greatest Financial Impact

Risks from Strategic Transformation and Integration
We are in a constant process of strategic adjustments. If we cannot imple-
ment our plans as expected, we are exposed to certain risks. For example, 
the benefits of the measures may be less than originally estimated, they 
may have a later impact than anticipated, or they may not have any effect 
at all. On the other hand, constant growth also amplifies the complexity 
of integrating successful transactions, our pipeline, locations, processes 
and interfaces. Any of these factors – alone or in combination – could 
have a negative impact on our business, net assets, financial position and 
operating results. The transformation is being addressed through vari-
ous strategic initiatives, including in particular the expansion of existing 
departments and cross-disciplinary teams as well as the expansion of 
our IT support and the underlying process landscape. The financial risk is 
assessed as high and has primarily a medium and long-term impact.

Risks Related to Commercial Products
BioNTech’s future success depends largely on our ability to successfully 
commercialize our development candidates. The commercial function is 
constantly being enlarged and its processes refined in order to consoli-
date our position and establish ourselves as the market leader. Commer-
cial scaling and the interaction between medical and public affairs are 
time-critical components. The financial risk is assessed as high.

In  2020,  our  COVID-19  vaccine  was  our  first  commercial  product 
launched on the market and an effective component in the fight against 
the COVID-19 pandemic. Revenues projected on the basis of assump-
tions are subject to fluctuations and may thus fall short of our own expec-
tations. These fluctuations can be caused, for example, by an incorrect 
assessment of market size or unforeseen changes in market demand. 
This also includes the transition to standard treatment, securing the sup-
ply chain and adapting our vaccine doses to the changing distribution 
channels. Changes in the requirements for our vaccine, missed or delayed 
adaptation to new virus variants or even superior products from compet-
itors could also have an aggravating effect. We continuously monitor and 
analyze market and industry developments in order to identify market 
entry barriers, growing competition or changes in health legislation at an 
early stage and are further expanding the internal capacities needed to 
do so. In addition, we are in active exchange with government represen-
tatives, health insurance companies and other payers. The financial risk is 
assessed as medium.

The various contracts with our collaboration partners and the associat-
ed profit share are subject to certain expectations on our side. Despite 
various consultations and our own assessment, actual results may fall 
short of our expectations, e.g. due to lower revenues or market shares in 
our partners’ regions as well as increased costs on our partners’ side. In 
order to be able to better assess the developments, we are in intensive 
and constant exchange with our partners. The financial risk is assessed 
as medium.

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  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Research and Development Risks
There are currently 22 product candidates in oncology and seven product 
candidates in infectious diseases in clinical development. Our main activ-
ity therefore continues to be research and development and the super-
vision of clinical trials. Naturally, this also involves the greatest risks. For 
scientific, procedural or regulatory reasons, product candidates may not 
be developed to market maturity, or only with a delay. Likewise, despite 
optimal preparation, unforeseeable complications or side effects may 
occur in the course of clinical trials, which in the worst case could lead 
to legal disputes and compensation payments. The increasing number 
of candidates in our product pipeline also has a growing impact on the 
Company’s risk situation. We constantly monitor the development of our 
industry and the market in order to address uncertain factors during the 
research and development of our candidates in oncology and infectious 
disease (e.g. clinical care costs, the number of treatable patients, possi-
ble additional costs due to delays in clinical trials, a more difficult patient 
search or an additional trial to collect additional data). The financial risk is 
assessed as high.

People Risks
Our workforce plays a crucial role in our transformation. The skills of our 
employees are an important factor for our business success. If we are 
unable to attract or retain a sufficient number of experts, this could have a 
negative impact on our business in the future. New processes and capaci-
ties are being developed and built up to counteract the bottleneck caused 
by the generally high market demand for the recruitment of new employ-
ees and relevant specialist staff. The financial risk is assessed as high.

Geopolitical and External Risks
Our constant global expansion also increases the regulatory require-
ments placed on us. For example, working with collaboration partners 
in different countries and regions leads to additional requirements and 
regulations that we have to consider. This includes topics such as data 
protection, animal welfare and the protection of human rights. The finan-
cial risk is assessed as high.

Events on a global scale are also the focus of strategic consideration and 
include climate change and associated extreme weather events such as 
floods or droughts. We also monitor the effects of geopolitical tensions 
and conflicts in various regions of the world with a view to their potential 
impact on our business activities. These include armed conflicts such as 
those in Ukraine and the Middle East and their potential escalation, as well 
as trade conflicts. Even though the financial risk is currently assessed as 
low, the situation is being closely monitored.

Such tensions can have further consequences, such as a high inflation 
rate, disrupted supply chains, for example due to import restrictions, sup-
ply bottlenecks or resource shortages. These are continuously monitored 
and evaluated by our Business Continuity Management function. The 
financial risk is assessed as low.

Physical and IT Security Risks
The protection of our data and the security of our information also in-
cludes unauthorized access – from outside or inside – to our supply chain, 
infrastructure or intellectual property as well as extortionist acts, deni-
al-of-service attacks, fraud and phishing or even a global IT blackout. We 
take various measures to counteract these risks; for example, we contin-
uously enhance our security policies and guidelines and perform IT risk 
and application security assessments; a vulnerability scanner, awareness 
training for our employees and incident management function have been 
set up. The residual financial risk is classified as medium.

The continued visibility of the Company and the growing international 
presence have diversified security risks. Physical security risks include 
criminal threats against the assets of BioNTech, harassment of employ-
ees, unauthorized access and other undesired acts against BioNTech’s 
operations. With a security transformation program, awareness training 
and the implementation of corresponding physical security standards, 
BioNTech aims to achieve and uphold a globally consistent level of pro-
tection for all BioNTech representatives and assets. A medium residual 
financial risk remains.

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  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Legal, IP and Insurance Risks
The legal risks that are currently relevant to us can be grouped into two 
categories: contractual risks and patent-related risks.

sources  of  information.  The  necessary  processes  and  systems  have 
been established and are constantly being refined. The residual financial 
risk is classified as low, but reputational damage could be high.

On the contractual side, we are confronted with possible breaches of 
contract. Different interpretations of the contracts, the claims regulated 
in them and the allocation of revenues and costs could lead to disputes. 
Where the recognition criteria are met, provisions are made to counter 
this risk. We assess this as a medium residual financial risk.

The withholding and deduction of taxes on remuneration for the transfer 
of the use or the permission to use rights, in particular copyrights and 
intellectual property rights, is actively monitored by our Tax department. 
The financial risk is considered to be low, but reputational damage could 
be high.

It is possible that not all events or different events are fully insured. Our 
constant growth makes it difficult for insurance service providers to as-
sess us, coverage amounts and related premiums may be set too high or 
too low. If coverage amounts are too low, there is a risk that events may not 
be fully covered, while excessively high coverage would impair our liquid-
ity. We have established a central insurance management function and 
work with specialized insurance brokers and insurers with experience in 
the pharmaceutical industry. We liaise with our insurers to address any 
discrepancies. Identified risks are evaluated and mitigated whenever nec-
essary. We assess this as a medium residual financial risk.

In addition, in the normal course of business, we could from time to time 
unintentionally infringe protected intellectual property of others. These 
patent-related risks are countered by continuous monitoring of patent 
applications. In addition, in such cases, we continuously assess whether 
the related circumstances will change in the future, including whether it 
may be necessary to recognize a provision and whether there are poten-
tial indemnification claims against such allegations. The financial risk is 
assessed as low.

Intentional or unintentional infringement of our intellectual property by 
third parties is currently considered to be a low financial risk, but would 
have mainly long-term effects.

Compliance and Regulatory Risks
The rapid growth of recent years augments the risk of a delay in quarterly 
or annual financial statements. Increased media attention and regulatory 
requirements also have an impact on timelines, as does the interaction 
between internal departments and external collaboration partners as 

In Compliance & Business Ethics, the focus is on combating corruption, 
bribery and money laundering. In addition, processes have been put in 
place and various training courses, guidelines and policies are available 
to our employees to actively address dealing with healthcare experts, 
conflicts of interest and discrimination. The financial risk from such mis-
conduct is classified as low, but it could result in high reputational damage.

Processes and responsibilities need to keep pace and evolve with the 
rapid growth. It may not be possible to adequately meet the requirements 
of the Sarbanes-Oxley Act (U.S. federal law designed to improve report-
ing by companies using the U.S. public capital market). The confidence 
of the market or individual investors could be damaged. To counteract 
this, the internal control system is constantly being expanded and further 
developed. The financial risk is low.

Financial Risks
A large part of the incoming payments are in U.S. dollars. Consequently, 
we incur an exchange rate risk for the funds required in euros. With the aim 
of preserving capital, surplus liquidity is invested in short and longer-term 
securities and at various banks as well as in money market funds with 
investment grade ratings, subject to limits defined in a risk policy. Coun-
terparty limits are derived from the respective banks’ credit default swaps 
(CDSs) and monitored on an ongoing basis. Any interest rate risks in this 
context can also lead to opportunities. We also identify exchange rate 
risks with regard to foreign currency investments. Exchange rate and in-
terest rate fluctuations can reduce the value of our financial positions. We 
limit the effects of the identified risks with the help of a coordinated and 
consistently implemented risk strategy. As a matter of principle, forward 
exchange transactions are concluded as hedging instruments. Our risk 

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  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

strategy also takes into account natural hedging relationships. In addition, 
developments on the financial markets are continuously monitored to 
enable us to react to exceptional events at short notice. The financial risk 
is assessed as low.

Sustainability Risks
Since the 2023 financial year, Risk Performance and Corporate Social 
Responsibility (CSR) have worked together to identify material sustain-
ability risks and integrate them into the company-wide risk management 
system. In 2023, the analyses focused on climate risks as identified by 
the Task Force on Climate-related Financial Disclosures (TCFD) and hu-
mans rights risks pursuant to the German Act on Corporate Due Diligence 
for the Prevention of Human Rights Violations in Supply Chains (LkSG), 
which has been applicable to BioNTech since January 1, 2023.

We integrate climate-related topics (climate risks pursuant to the TCFD 
and targets in accordance with the Science Based Targets initiative or 
SBTi) into risk management on a continuous basis. BioNTech added a 
separate category of potentially relevant financial and physical impacts of 
climate change to its corporate risk management in 2023 and continues 
to work on integrating more specific climate-related risk categories into 
risk management. The sustainability report for the 2023 financial year 
contains an overview of the climate risks identified as being of relevance 
for us and of climate risk governance and strategy. Metrics and targets 
(not externally audited) for assessing and managing relevant climate-re-
lated risks are published in the 2023 Sustainability Report and on our 
website at www.biontech.de. The climate targets for 2030 in accordance 
with the SBTi were confirmed by the SBTi in January 2024. 

BioNTech has been conducting a proactive risk assessment since 2023 
in order to identify potential and actual human rights and environmental 
risks and incidents in accordance with the LkSG at an early stage and to 
take action to prevent and mitigate them. The risk assessment will be car-
ried out annually and, if necessary, on an ad hoc basis to assess potential 
risks arising from significant changes in the Company’s business activities 
or business relationships or if specific concerns arise in relation to human 
rights and environmental risks under the LkSG. In 2023, BioNTech car-
ried out risk assessments for its own business activities at both abstract 
and concrete levels, using information from external experts and internal 

sources. The risk assessment along the supply chain was based on coun-
try-specific and industry-specific risk data. The identified human rights 
risks are recorded in the Company’s risk management system. One focus 
of the human rights management process in 2023 was the discussion and 
preparation of the integration of human rights risks into the Company’s 
risk management system. The integration is being coordinated by the 
Human Rights Officer and BioNTech’s risk management function and will 
continue in 2024. The establishment of formal governance structures will 
also continue in 2024.

We differentiate between human rights risks in our own sphere of respon-
sibility and those in our supply chain. If we fail to comply with the legal 
requirements or do not handle reported violations in a timely or appro-
priate manner, we could be excluded from public tenders, suffer a loss of 
reputation or be fined. The financial risk for BioNTech is low in both areas 
(outside-in perspective).

On the other hand, the more we drive forward our transformation guided 
by the SBTi targets, the greater the transition risks will be. This can have a 
negative impact on our business activities and on our material, production 
and transportation costs. The financial impact on BioNTech is assessed 
as low.

We also consider the physical effects of climate risks, such as the impact 
of heatwaves, flooding or rising sea levels on our business units or our 
supply chain. The financial impact on BioNTech is currently considered to 
be low, but could rise in the longer term (outside-in perspective).

4.2.3 Internal Control System and Internal Audit

Internal Control System
Our internal control system (ICS) is designed to provide reasonable as-
surance regarding the reliability of financial reporting and the preparation 
of our financial statements for external reporting purposes in accordance 
with International Financial Reporting Standards (IFRS) or the German 
Commercial Code (HGB). Having listed our share on the Nasdaq Global 
Select Market, we have established our internal control system based on 
SOX regulations (Sarbanes-Oxley Act Section 404). 

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  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The standard ICS process is depicted in an ICS lifecycle, comprising the 
six steps presented below that are carried out either consecutively or in 
parallel:

  Scoping phase

  Testing of effectiveness

  Discussion of test results

  Monitoring of activities

  Quality assurance of the self-assessments

  ICS reporting

The results of the testing are communicated regularly to the Manage-
ment Board and Supervisory Board and approved in connection with the 
annual financial statements. The scope of the ICS is defined across all 
processes. The test results include financial reporting topics as well as 
further processes and topics from general areas, such as treasury, tax, IT, 
compliance and operational topics.

Based on the COSO model (Committee of Sponsoring Organizations of 
the Treadway Commission), our internal control system for financial re-
porting is divided into five components: control environment, risk assess-
ment, control activities, information and communication, and monitoring 
of the internal control system.

The effectiveness of internal control over financial reporting is regularly 
reviewed and assessed against the COSO components in accordance 
with Section 404 SOX. As of December 31, 2023, the control system over 
financial reporting was assessed as effective by our Management Board.

Internal Audit
The Internal Audit function was newly implemented in October 2022. In-
ternal Audit reports to the CEO and the Audit Committee. As an indepen-
dent audit and consulting function without operational responsibility, In-
ternal Audit performs audits of organizational units, processes, corporate 
functions, applications and projects selected according to a risk-based 
approach on behalf of the Management Board and the Audit Committee. 
Various audits were conducted in the 2023 financial year. Audit findings 
lead to agreed actions that are overseen by Internal Audit until they have 
been fully implemented. Regular reporting to the Audit Committee and 
Management Board on the implementation status of the agreed actions 
has been established. 

4.2.4  Assessment of the Internal Control System and Risk Management 

System by the Management Board

The company-wide risk situation is evaluated twice-yearly at Manage-
ment Board meetings. The results of the internal control process are pre-
sented to the Audit Committee once a quarter and an overall assessment 
is given of the adequacy and effectiveness of the ICS and RMS. On this 
basis, the Management Board is not aware of any indications that our ICS 
and RMS were not appropriate or not effective overall as of December 31, 
2023.

We  are  convinced  that  we  will  be  able  to  master  challenges  and  take 
advantage of opportunities in the future without taking unjustifiably high 
risks. In doing so, we strive for a balanced relationship between opportu-
nities and risks. Our aim is to increase added value for our stakeholders by 
analyzing and seizing new opportunities.

4.2.5 Assessment of the Overall Risk Situation by the Management Board

The assessment of the overall risk situation is the result of the consolidat-
ed consideration of all significant risk categories and individual risks. 

Given systemic limitations, the design of internal control over financial 
reporting and the diligence of control implementation do not provide ab-
solute assurance that the financial reporting objectives will be achieved 
and misstatements will always be prevented or detected.

At the time the management report was prepared, the aforementioned 
risks did not pose any threat to the continued existence of BioNTech SE 
and its affiliated subsidiaries.

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  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

4.3 Opportunity Report

In pursuit of our vision, we are focused on transforming the treatment of 
cancer and infectious diseases and creating long-term value for patients, 
society and our shareholders through innovative and personalized med-
icines and therapies that harness the full potential of the human immune 
system. Based on the key building blocks listed below, we believe we are 
well positioned to provide people around the world with access to our 
therapies and medicines and to ensure that they benefit from them. 

Pipeline of Clinical Product Candidates

Underpinning our vision is our understanding and long experience in im-
munology. We are a multi-technology company with specific expertise in 
the development of mRNA-based therapeutics, immunomodulators such 
as monospecific and bispecific antibodies and targeted therapies such as 
ADCs and CAR-T cell therapies. We believe that by combining comple-
mentary treatment modalities, we can leverage the full potential of each 
technology to develop precise and personalized treatments that increase 
the likelihood of therapeutic success, reduce the risk of treatment resis-
tance and reach a broader patient population. We use AI and machine 
learning to build our pipeline, identify and optimize molecules and accel-
erate workflows on our journey to becoming an AI-integrated company. 

Our diversified product portfolio encompasses a large array of product 
candidates with a growing pipeline of investigational compounds in ad-
vanced development. The breadth of the pipeline should enable us to 
advance product candidates to approval, while at the same time cush-
ioning the impact of candidates that fail to reach market on the Compa-
ny’s overall performance. There are currently 22 product candidates in 
oncology and seven product candidates in infectious diseases in clinical 
development. In 2023, we initiated three Phase 1 clinical trials in infectious 
disease for mRNA-based prophylactic vaccine candidates against the 
herpes simplex  virus,  tuberculosis  and mpox. In oncology, we  started 
seven trials with product candidates from across a range of technologies 
against a number of solid tumors: ADCs (one Phase 1/2 and one Phase 3 
trial), monoclonal antibodies (one Phase 3 trial), bispecific antibodies (one 
Phase 2 trial) and mRNA-based product candidates (two Phase 2 trials).

The rapid development, successful commercialization and delivery of 
our COVID-19 vaccine based on our proprietary mRNA technology has 
demonstrated the potential of immunotherapies. The speed and success 
of developing a vaccine based on mRNA technology has also demon-
strated that not only can highly effective and safe vaccines be produced 
based on this technology, but that mRNA technology may also enable 
potentially faster product development and shorter production cycles 
than conventional vaccine technologies. In 2023, we and Pfizer continued 
our global COVID-19 vaccine leadership with the market launch of the 
Omicron XBB.1.5-adapted monovalent COVID-19 vaccine. Furthermore, 
we are focusing on building a sustainable respiratory infectious disease 
vaccine business, leveraging our existing COVID-19 vaccine franchise. In 
addition to our marketed product Comirnaty, we are collaborating with 
Pfizer on our development program for a shingles vaccine and for a com-
bination vaccine against COVID-19 and influenza designed to potentially 
address two serious respiratory diseases with a single vaccine. 

Our long-term oncology vision is to expand the number of available treat-
ment options for cancer patients. We aim to address the full continuum of 
cancer treatment by developing novel therapies to best serve the needs 
of cancer patients from adjuvant to late-stage settings. We aim to achieve 
this  by  building  a  diverse  toolkit  and  clinical  portfolio  with  synergistic 
mechanisms of action. To increase the potential efficacy of our immuno-
therapies, we develop product candidates that are precisely targeted. By 
combining compounds with synergistic mechanisms of action, such as 
the combination of our FixVac immunotherapy (CARVac) with our novel 
CAR-T therapies, we aim to potentially increase the efficacy of our thera-
pies and counteract resistance mechanisms. Our objective is to combine 
immunomodulators and/or targeted therapies with our mRNA cancer 
vaccines to polyspecifically target and potentially cure cancer.

We believe we are well positioned to develop the next generation of im-
munotherapies that have the potential to change treatment paradigms for 
therapies against cancer, infectious diseases and other serious diseases, 
and significantly improve clinical outcomes for patients. 

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  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

We continued to build our pipeline in 2023 and are currently conducting 
11 Phase 2 and 3 clinical trials in various modalities and indications as 
monotherapy or in combination with a standard therapy. Our future rests 
on the four pillars of our COVID-19 franchise, the oncology pipeline, the 
infectious disease pipeline and our strong financial position. In 2024, we 
will raise our R&D spending, particularly in oncology, in order to conduct 
potential pivotal studies. We plan to have ten potentially registrational 
trials running by the end of 2024. We will continue to pursue our active 
business development and M&A strategy. The aim is to secure several 
oncology product approvals by 2030 and to have a leading pipeline for 
late-stage infectious diseases. With our strong financial position, our mar-
ket-leading COVID-19 vaccine and our expanding oncology and infectious 
disease pipeline, we believe we are well positioned to execute our vision 
of pioneering novel medicines against cancer, infectious diseases and 
other serious diseases.

Research and Development Employees

As of December 31, 2023, the BioNTech Group employed 6,292 peo-
ple, 42.5% of whom worked in research and development. As of Decem-
ber 31, 2022, 38.1% of the Group’s 4,692 employees worked in research 
and  development.  As  of  December  31,  2023,  BioNTech  SE  employed 
3,166 people (December 31, 2022: 2,304), 55.1% of whom worked in re-
search and development (December 31, 2022: 54.6%). The large num-
ber of employees in R&D will enable us to continue and accelerate basic 
scientific research and, above all, clinical research, particularly for our 
approval-relevant studies. 

Production

In 2020 to 2022, to accommodate the production of the COVID-19 vac-
cine we not only expanded our internal production capacities, most nota-
bly by acquiring the plant in Marburg, which is now one of the world’s larg-
est mRNA production facilities with a production capacity of up to three 
billion mRNA vaccine doses per year, but also built a global supply chain 
and production network. We are working hard to build or lease the labora-
tories, production facilities and office space necessary for the Company’s 
further expansion and are convinced that the best way for us to expand 

our production capacities is to enlarge our existing internal production 
facilities and build additional new in-house facilities rather than outsource 
to external partners with the greater dependencies this would entail.

Since the beginning of 2023, a further manufacturing facility has been 
in operation in Marburg, where we are manufacturing plasmids for our 
clinical trials. Establishing our own plasmid DNA production enables us to 
manufacture the starting materials for mRNA- and cell-based drugs more 
flexibly and autonomously. In Mainz, the semi-automation of processes 
under  the  iNEST  (individualized  neoantigen-specific  immunotherapy) 
program has resulted in the faster production of individualized mRNA 
cancer vaccines for clinical use. The aim is to improve processes in order 
to reduce turnaround times further.

We also plan to build our own fully integrated mRNA production sites in 
Asia and Africa with capacity to produce several hundreds of millions of 
doses of various mRNA-based vaccines. Our plans in Asia include con-
structing a fully integrated mRNA manufacturing facility in Singapore, with 
the option of extending it to produce other drug classes, such as cell ther-
apies. The facility will be integrated into the Company’s global produc-
tion network and is an important building block for supplying the Asian 
region with our COVID-19 vaccine and other future products in oncology 
and  infectious  disease.  Using  a  novel  approach,  we  have  also  devel-
oped turnkey mRNA production facilities based on a container solution 
called BioNTainer, which are designed to enable scalable mRNA vaccine 
production. Several shipping containers for our first BioNTainer finished 
construction in Europe, underwent quality checks, were prepared for 
shipment and arrived in Kigali, Rwanda, in March 2023. The facility being 
established there will become a node in a decentralized and robust end-
to-end manufacturing network in Africa. Vaccines to be manufactured in 
Africa will be dedicated to people residing in member states of the African 
Union. In addition, we announced in December 2023 that we also plan to 
build a BioNTainer-based production facility in Victoria, Australia.

Our continually growing global manufacturing capacity and our global 
COVID-19 vaccine supply chains and manufacturing network give us the 
opportunity to provide people around the world with fast and easy access 
to state-of-the-art medicines and therapies. In addition, the increasing 

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  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

digitalization and automation of business processes, supported by effec-
tive process management, creates opportunities for us to create addition-
al value and increase efficiency. 

Commercialization

Last year, we continued our transformation into a globally operating, prof-
itable  and  fully  integrated  biotechnology  company.  The  main  focus  in 
2023 was on ensuring the best possible supply of our COVID-19 vaccine. 
The financial resources gained in 2021, 2022 and 2023 have put us in a 
good position to accelerate the expansion of our portfolio in the field of 
oncology and to open up further therapeutic areas and sales markets. We 
remain on track for assuming a leading role in the rapidly growing market 
for immunotherapies in the coming years.

With the commercial team set up in 2020 and the establishment of two 
sales companies in Germany and Turkey, we are creating the necessary 
conditions to also be able to market future products on our own and thus 
significantly reduce dependency on our partners. The expansion of com-
mercial capacity in preparation for product launches should be complet-
ed by the end of 2025 and allow us to achieve commercial readiness in 
oncology in multiple countries.

We also continued with the expansion of our digital commercial ecosys-
tem to enable even better interaction with the Company’s stakeholders, 
including a personalized customer journey, a sales performance program 
and a smart learning platform. In the future, we will continue to make use 
of opportunities to expand our own know-how to include promising com-
plementary technologies such as artificial intelligence (AI) and machine 
learning (ML) and strengthen production capacities by making targeted 
acquisitions and investments in other companies.

The acquisition of InstaDeep Ltd., headquartered in London, United King-
dom, will strengthen our pioneering position in the field of AI-powered 
drug discovery, design and development. In this context, the increased at-
tention on our Company due to the successful development and produc-
tion of a COVID-19 vaccine as well as its commercialization also offers the 
opportunity to enter into new partnerships with leading global companies, 

foundations and academic research institutions for the development and 
distribution of further products. In 2023, we forged a strategic partnership 
with the UK government with the aim of providing personalized mRNA 
cancer therapies for patients, either in clinical trials or as authorized treat-
ments. An R&D hub is being established in Cambridge for this purpose. 
Last but not least, in December last year BioNTech signed a strategic 
partnership agreement with the State of Victoria in Australia to strengthen 
the mRNA ecosystem.

Team and Corporate Culture

Standing behind the great successes of the past three years are our now 
more than 6,000 employees. In addition, we have a management team 
consisting of renowned scientists, experienced entrepreneurs and the 
biotechnology investors who support us.

In order to be able to continue our successful development, it is of great 
importance for us to continue to attract the best minds to the Company 
in the future. We owe our high profile worldwide to Project Lightspeed 
and the rapid and successful development of the COVID-19 vaccine. This 
improves our chances of attracting global talent to BioNTech. 

Our corporate culture, which puts people first, and our inclusive and sup-
portive  working  environment  speak  for  themselves:  For  example,  our 
BioNTech emotional well-being program led to the award of best-in-class 
employer in the United States from the Gallagher Biotech Benefits Alli-
ance. In Germany, the Company was recognized in an independent rank-
ing as the best employer in Germany in the pharmaceutical and medical 
technology sector. BioNTech’s commitment to talent does not end with 
the Company’s own needs: By participating in programs such as the GIZ’s 
“Africa is coming!” or the WHO’s “Tropical Disease Research”, BioNTech 
is involved in capability-building initiatives that extend beyond the Compa-
ny. BioNTech sees maintaining and developing our corporate culture as a 
cornerstone of our strategy to manage the expected future growth of our 
organization. We have set up a Culture Campus, an independent depart-
ment that reports directly to CEO Ugur Sahin and CMO Özlem Türeci, to 
bring together employees from a wide range of disciplines who join forces 
to further develop the culture rooted in the founding team’s vision. 

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  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Embedding the success factors of our leadership and corporate culture 
is the core task of cultural work at BioNTech – promoting cohesion, a pio-
neering spirit and a safe environment in which mistakes are accepted and 
viewed as elements of a learning process.

There are many helping hands – the number of cultural ambassadors 
has grown to more than 100 colleagues from all over the world in the last 
two years. They are committed to promoting a sense of community and 
developing the corporate culture through various initiatives, such as open 
office  hours,  an  internal  networking  hub  (“Connect  with  Colleagues”) 
and workshops. The success principles of our culture are systematically 
reflected in our HR processes and offerings and in our communication – 
from onboarding to company-wide buddy circles and leadership training. 

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  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

5  CORPORATE GOVERNANCE 

DECLARATION PURSUANT TO 
SECTION 315D IN CONJUNCTION 
WITH SECTION 289F HGB

Code, is issued in connection with the Corporate Governance Declaration 
pursuant to Section 315d in conjunction with Section 289f HGB: 

BioNTech SE has complied and will continue to comply with all recom-
mendations of the Code as amended on April 28, 2022, with the exception 
of the points listed below. 

5.1  Declaration on the Corporate Governance Code 

Pursuant to Section 161 AktG

The German Stock Corporation Act (AktG) requires that the Manage-
ment Board and Supervisory Board of German companies listed on a 
stock exchange regulated and supervised by a state-recognized body 
issue an annual declaration either (i) stating that the recommendations of 
the German Corporate Governance Code, or “Code” have been complied 
with or (ii) listing the recommendations with which the Company has not 
complied and explaining the reasons for the deviation from the recommen-
dations of the Code (Declaration of Conformity). There is no obligation to 
comply with the recommendations or suggestions of the Code. A listed 
company in this sense is obliged to further indicate in this annual declara-
tion whether it intends to comply with the recommendations or to list the 
recommendations it does not intend to comply with in the future. This state-
ment shall be made publicly available online. 

If the company changes its policy with regard to certain recommenda-
tions between these annual statements, it must disclose this fact and ex-
plain the reasons for the deviation from the recommendations. Non-com-
pliance with the suggestions also contained in the Code in addition to the 
recommendations does not have to be disclosed.

The Management Board and Supervisory Board have dealt in detail with 
the recommendations of the Code and, on February 27, 2024, issued the 
following Declaration of Conformity pursuant to Section 161 para. 1 of the 
German Stock Corporation Act (AktG), which, in accordance with the 

  According to Item B.1 of the Code, the Supervisory Board shall take 
diversity in account in the composition of the Management Board. On 
March 8, 2023, the Supervisory Board of the Company set the target 
for the proportion of women on the Management Board at 25%. The 
deadline by which this target is to be achieved was set at December 
31, 2025. James Ryan was appointed to the Management Board as 
Chief Legal Officer effective as of September 1, 2023. The position of 
Chief Legal Officer did not exist in the Company before this date. The 
Supervisory Board considered the appointment of a representative of 
the Company’s Legal department to the Management Board to be im-
portant in order to attain the Company’s strategic and economic objec-
tives. As Senior Vice President Legal & IP and General Counsel, James 
Ryan had been head of the Legal department for many years and was 
the most suitable candidate for this position due to his great expertise 
and the trust placed in him by the Supervisory Board. The appointment 
was made after careful consideration and discussion and, in the opin-
ion of the Supervisory Board, was in the best interests of the Company. 
The Supervisory Board addresses the newly set diversity targets for 
the Management Board and will take these into account in the future.

  According to Item B.3 of the Code, the initial appointment of Man-
agement Board members shall be for a period of no more than three 
years. In a departure from this, the Management Board member James 
Ryan was appointed for a period of four years with effect from Sep-
tember 1, 2023. In view of James Ryan’s many years of experience in 
the Company as Senior Vice President Legal & IP and General Coun-
sel as well as his professional qualifications, the Supervisory Board 
considered an initial appointment for four years to be necessary and 
appropriate. Furthermore, the Supervisory Board considered the initial 
appointment for a four-year period to be in the best interests of the 
Company, enabling the implementation of long-term strategic corpo-
rate goals and decisions.

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  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

  According to Item C.7 of the Code, it is recommended that more 
than half of the members of the Supervisory Board be independent of 
the Company and its Management Board. Accordingly, a Supervisory 
Board member is independent of the Company and its Management 
Board if he or she has no personal or business relationship with the 
Company or its Management Board that may cause a substantial – 
and not merely temporary – conflict of interest. In assessing indepen-
dence, the length of service on the Supervisory Board is to be taken 
into account, among other factors. Despite the fact that two of the six 
members of the Supervisory Board have served on the Superviso-
ry Board for longer than the 12 years recommended by the Code, all 
members of the Supervisory Board are considered independent. The 
Supervisory Board considers it advantageous and essential for the 
Company to retain the knowledge and experience currently available 
on the Supervisory Board. This includes many years of knowledge of 
the Company and its industry as well as comprehensive professional 
knowledge in the areas of finance, economics, science and the capital 
markets, which is particularly important in view of the current steady 
global growth and transformation of the Company. The duration of the 
membership of the two Supervisory Board members Helmut Jeggle 
and Michael Motschmann does not conflict with their respective inde-
pendence due to their longstanding ties with the Company and their 
economic independence from the Company as well as the absence of 
other matters that could give rise to possible conflicts of interest (see 
Item C.8 of the Code).

5.2  Composition and Working Practices of the Management 

Board, Supervisory Board and Committees

We are a European public company with limited liability (Societas Euro-
paea or SE) (also referred to as European stock corporation, and in the 
official terminology of the European legislation referred to as European 
public limited liability company), having its seat in Germany. We have cho-
sen to have a two-tiered SE structure. Hence, our corporate bodies are 
the Management Board (Vorstand), the Supervisory Board (Aufsichtsrat) 
and the shareholders’ meeting (Hauptversammlung). Our Management 
and Supervisory Boards are entirely separate, and, as a rule, no individual 
may simultaneously be a member of both boards.

Our Management Board is responsible for the day-to-day management of 
our business in accordance with applicable laws, our Articles of Associa-
tion (Satzung) and the Management Board’s internal rules of procedure 
(Geschäftsordnung). Our Management Board represents us in our deal-
ings with third parties.

The principal function of our Supervisory Board is to supervise our Man-
agement Board. The Supervisory Board is also responsible for appointing 
and removing the members of our Management Board, representing us in 
connection with transactions between a current or former member of the 
Management Board and us, and granting approvals for certain significant 
matters.

Our Management Board and our Supervisory Board are solely respon-
sible for, and manage, their own areas of competency (Kompetenztren-
nung); therefore, neither board may make decisions that, pursuant to ap-
plicable law, our Articles of Association or the internal rules of procedure 
are the responsibility of the other board. Members of both boards owe a 
duty of loyalty and care to us. In carrying out their duties, they are required 
to exercise the standard of care of a prudent and diligent businessperson. 
If they fail to observe the appropriate standard of care, they may become 
liable to us.

In carrying out their duties, the members of both boards must take into ac-
count a broad range of considerations when making decisions, including 
the interests of our shareholders, employees, creditors and, to a limited 
extent, the general public, while respecting the rights of our shareholders 
to be treated on equal terms. Additionally, the Management Board is re-
sponsible for implementing an appropriate and effective internal control 
system and risk management system.

Our Supervisory Board has comprehensive monitoring responsibilities. 
To ensure that our Supervisory Board can carry out these functions prop-
erly, our Management Board must, among other duties, regularly report 
to our Supervisory Board regarding our current business operations and 
future business planning (including financial, investment and personnel 
planning). In addition, our Supervisory Board or any of its members is enti-
tled to request special reports from the Management Board on all matters 
regarding the Company, our legal and business relations with affiliated 

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  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

companies and any business transactions and matters at such affiliated 
companies that may have a significant impact on our position at any time.

Under German law, our shareholders have, as a general rule, no direct 
recourse against the members of our Management Board or the mem-
bers of our Supervisory Board in the event that they are believed to have 
breached their duty of loyalty and care to us. Apart from when we are 
unable to fulfill our third-party obligations, tortious conduct to board mem-
bers or other special circumstances, only we have the right to claim dam-
ages against the members of our two boards. 

We may waive these claims to damages or settle these claims only if at 
least three years have passed since a claim associated with any violation 
of a duty has arisen and only if our shareholders approve the waiver or 
settlement at a shareholders’ meeting with a simple majority of the votes 
cast, provided that no shareholders who in the aggregate hold one-tenth 
or more of our share capital oppose the waiver or settlement and have 
their opposition formally recorded in the meeting’s minutes.

5.2.1 Supervisory Board

German law requires that the Supervisory Board consists of at least three 
members, while a company’s articles of association may stipulate a cer-
tain higher number. Our Supervisory Board consists of six members as 
of December 31, 2023. As we are not subject to co-determination, the 
members of our Supervisory Board are all elected by the shareholders’ 
meeting in accordance with the provisions of the SE Regulation and the 
German Stock Corporation Act (Aktiengesetz). 

The following table sets forth the names and functions of the current 
members of our Supervisory Board, their ages as of December 31, 2023, 
their terms (which expire on the date of the relevant year’s general share-
holders’ meeting) and their principal occupations and other relevant Su-
pervisory Board mandates outside of our Company:

Name (function)

Age

Term 
expires

Principal occupation  
(other relevant mandates)

Helmut Jeggle  
(Chair of the  
Supervisory Board)

53

2026

Ulrich Wandschneider, 
Ph.D. (Deputy Chair of 
the Supervisory Board)

62

2027

Baroness  
Nicola Blackwood(1)

44

2027

Prof.  
Christoph Huber, M.D. (2)

79

2023

Prof.  
Anja Morawietz, Ph.D.

46

2026

Michael Motschmann

66

2027

Prof.  
Rudolf Staudigl, Ph.D.

69

2026

Managing partner and entrepreneurial 
venture capital investor of Salvia GmbH 
(Supervisory Board member 4SC AG, 
AiCuris AG, APK AG and Tonies SE)

Managing director of beebusy  
capital GmbH and independent 
consultant to companies in the life 
science and healthcare sector

Managing Director and Chair of Oxford 
University Innovations Limited (Equity 
Partner, ReCode Health Ventures LLC, 
Trustee and Director of the Alan Turing 
Institute, Chair of the Advisory Board of 
Genomics England Limited)

Professor emeritus at the Johannes 
Gutenberg University Mainz (Deputy 
Chair of the Supervisory Board Tirol 
Kliniken GmbH)

Certified Public Accountant and 
Management Consultant, Professor 
of External Accounting and General 
Business Administration at the 
Nuremberg University of Applied 
Sciences Georg Simon Ohm

Member of the Management Board 
and head of equity investments of MIG 
Capital AG (Supervisory Board  
member AFFiRiS AG, APK AG, 
 HMW-Emissionshaus AG and  
HMW-Innovations AG)

Independent consultant (Member of 
the Supervisory Board of TÜV Süd 
Aktiengesellschaft, member of the 
Supervisory Board of Groz-Beckert KG 
(Deputy Chair))

(1)  Appointed effective as of May 25, 2023. 

(2)  Member of the Supervisory Board until May 25, 2023

The business address of the members of the Supervisory Board is the busi-
ness address of BioNTech: An der Goldgrube 12, 55131 Mainz, Germany.

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  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The competence profile of the members of the Supervisory Board is as 
follows as of December 31, 2023:

Qualification/name (function)

(Biotech) industry experience

(Biotech) industry sales and marketing

Management

Innovation, research and development

Accounting, auditing and controlling  
(including sustainability reporting)

Compliance, internal controls and risk 
management

Human resources

Digitalization

International experience/relevant markets

CSR/sustainability 

Elected to the Supervisory Board of the 
Company for the first time 

End of term

Independence 

Year of birth 

Gender

Helmut Jeggle  
(Chair of the 
Supervisory  
Board)

Ulrich 
Wandschneider, 
Ph.D. (Deputy Chair 
of the Supervisory 
Board)

Baroness  
Nicola Blackwood

Prof.  
Anja Morawietz, 
Ph.D.

Michael 
Motschmann

Prof.  
Rudolf Staudigl, 
Ph.D.

x

x

x

x

x

2008

2026

x

1970

m

x

x

x

x

x

x

x

x

x

x

2018

2027

x

1961

m

x

x

x

x

x

x

2023

2027

x

1979

f

x

x

x

x

x

x

2008

2027

x

1957

m

x

x

x

x

x

x

x

2022

2026

x

1954

m

x

x

x

x

x

2022

2026

x

1977

f

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  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

German law does not require the majority of our Supervisory Board mem-
bers to be independent and neither our Articles of Association (Satzung) 
nor the rules of procedure for our Supervisory Board provide otherwise. 
As  per  our  Supervisory  Board’s  assessment,  an  appropriate  number 
of shareholder representatives on the Supervisory Board (i.e. the en-
tire Supervisory Board) are independent if the Supervisory Board has 
two independent members. In addition to Ulrich Wandschneider, Nicola 
Blackwood, Anja Morawietz and Rudolf Staudigl, the Supervisory Board 
considers Helmut Jeggle and Michael Motschmann to be independent 
irrespective of the fact that they will soon have been members of the 
Supervisory Board for a period of more than 15 years. As stated in the dec-
laration to the German Corporate Governance Code, or the Corporate 
Governance Code, (Entsprechenserklärung) published by the Company 
on February 27, 2024 pursuant to Section 161 para. 1 of the German Stock 
Corporation Act (Aktiengesetz), which in accordance with the Corporate 
Governance Code is issued in connection with the Declaration pursuant 
to Section 315d in conjunction with Section 289f of the German Commer-
cial Code (HGB), the length of membership of the two named Supervisory 
Board members does not stand in the way of their independence. How-
ever, the rules of procedure for our Supervisory Board provide that the 
Supervisory Board should have an independent member with expertise 
in the field of accounting, internal control processes and auditing. Ulrich 
Wandschneider, Anja Morawietz, Michael Motschmann and Rudolf Stau-
digl fulfill this role. 

Under European law, a member of a supervisory board of an SE may be 
elected for a maximum term to be specified in the articles of associa-
tion, which must not exceed six years. Re-election, including repeated 
re-election, is permissible. The shareholders’ meeting may specify a term 
of office for individual members or all of the members of our Supervisory 
Board which is shorter than the standard term of office and, subject to 
statutory limits, may set different start and end dates for the terms of 
members of our Supervisory Board. Our Articles of Association provide 
for a term of approximately five years, depending on the date of the annual 
general shareholders’ meeting in the year in which the term of the relevant 
member is to expire.

The shareholders’ meeting may, at the same time as it elects the members 
of the Supervisory Board, elect one or more substitute members. The 
substitute members replace members who cease to be members of our 
Supervisory Board and take their place for the remainder of their respec-
tive terms of office. Currently, no substitute members have been elected 
or have been proposed to be elected.

Members of our Supervisory Board may be dismissed at any time during 
their term of office by a resolution of the shareholders’ meeting adopted 
by at least a simple majority of the votes cast. In addition, any member of 
our Supervisory Board may resign at any time by giving one month’s writ-
ten notice – or, in the event of cause, giving written notice with immediate 
effect – of his or her resignation to the Management Board.

Our Supervisory Board elects a chairperson and a deputy chairperson 
from its members. The deputy chairperson exercises the chairperson’s 
rights and obligations whenever the chairperson is unable to do so. The 
members of our Supervisory Board have elected Helmut Jeggle as chair-
person and Ulrich Wandschneider as deputy chairperson, each for the 
term of their respective membership on our Supervisory Board.

The Supervisory Board meets at least twice each calendar half-year. Our 
Articles of Association provide that a quorum of the Supervisory Board 
members is present if at least three of its members participate in the vote. 
Members of our Supervisory Board are deemed present if they attend the 
meeting via telephone or other (electronic) means of communication (in-
cluding via video conference) or submit their written vote through another 
member. Additionally, our Articles of Association allow for resolutions to 
be taken via telephone or other (electronic) means of communications 
(including via video conference).

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Resolutions of our Supervisory Board are passed by the vote of a simple 
majority of the votes cast unless otherwise required by law, our Articles 
of Association or the rules of procedure of our Supervisory Board. In the 
event of a tie, the chairperson of the Supervisory Board has the casting 
vote. Our Supervisory Board is not permitted to make management deci-
sions, but in accordance with European and German law and in addition to 
its statutory responsibilities, it has determined that certain matters require 
its prior consent, including:

  entering into certain large transactions;

  creating or holding any interest in businesses (except wholly owned 
subsidiaries) or disposing of shares in businesses (except for a sale of 
JPT); 

  issuing shares from authorized capital, unless the shares are issued 
pursuant to a redemption of stock appreciation rights; and

  acquiring treasury shares in return for valuable consideration.

The remuneration of the members of the Supervisory Board is described 
in the remuneration report, which is prepared for the 2023 financial year 
in accordance with the requirements of Section 162 AktG and published 
on the website. 

Each member of the Supervisory Board shall disclose any conflicts of 
interest to the Supervisory Board, especially those that may arise from 
providing advice or holding any offices or board positions at customers, 
suppliers, creditors or other third parties. Material conflicts of interest that 
are not merely temporary and that are specific to a particular Supervisory 
Board member shall result in this particular member leaving office. Our 
Supervisory Board also puts in place adequate measures to limit, prevent 
or resolve conflicts of interest in accordance with applicable legal require-
ments and the Company’s Conflicts of Interest Policy.

Our Supervisory Board conducted a self-assessment for the year ended 
December 31, 2023 by completing a written questionnaire. It covered all 
key aspects of the Supervisory Board’s work, including its committees, 
its composition, its competence profile, its main topics and its relationship 
with the Management Board. The results of the self-assessment have 
been evaluated and will be presented to the Supervisory Board to serve 
as a basis for discussion on current challenges and suggestions for im-
provement. Based on the evaluation of the self-assessment to date, the 
Supervisory Board, its committees and the Management Board continue 
to operate at a professional and cooperative level. No fundamental need 
for change was identified.

Supervisory Board Practices
Decisions are generally made by our Supervisory Board as a whole, how-
ever decisions on certain matters may be delegated to committees of our 
Supervisory Board to the extent permitted by law. The chairperson, or if 
he or she is prevented from doing so, the deputy chairperson, chairs the 
meetings of the Supervisory Board and determines the order in which 
the agenda items are discussed, the method and order of voting, as well 
as any adjournment of the discussion and passing of resolutions on indi-
vidual agenda items after a due assessment of the circumstances. Our 
Supervisory Board may designate further types of actions as requiring its 
approval.

In addition, each member of the Supervisory Board is obliged to carry 
out his or her duties and responsibilities personally, and such duties and 
responsibilities cannot be generally and permanently delegated to third 
parties. However, the Supervisory Board and its committees have the 
right to appoint independent experts for the review and analysis of spe-
cific circumstances in accordance with its control and supervision duties 
under applicable European and German law. We would bear the costs of 
any such independent experts that are retained by the Supervisory Board 
or any of its committees.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Pursuant to Section 107 para. 3 of the German Stock Corporation Act 
(Aktiengesetz), the Supervisory Board may form committees from among 
its members and charge them with the performance of specific tasks. The 
committees’ tasks, authorizations and processes are determined by the 
Supervisory Board. Where permissible by law, important powers of the 
Supervisory Board may also be transferred to committees.

The Supervisory Board has established an Audit Committee, a Compen-
sation,  Nominating,  Corporate  Governance  Committee  and  a  Capital 
Markets and Product Committee by resolution. The Product Committee 
was established as of October 1, 2023. Set forth in the table below are the 
members of the respective committees during the year ended December 
31, 2023.

Name of Committee

Members

Audit Committee

Prof. Anja Morawietz, Ph.D. (Chair),  
Prof. Rudolf Staudigl, Ph.D. and  
Ulrich Wandschneider, Ph.D.

Compensation, Nominating and 
Corporate Governance Committee

Prof. Rudolf Staudigl, Ph.D. (Chair),  
Baroness Nicola Blackwood (since May 25, 2023), 
Prof. Christoph Huber, M.D. (until May 25, 2023)  
and Michael Motschmann

Capital Markets Committee

Helmut Jeggle (Chair),  
Prof. Anja Morawietz, Ph.D. and Michael Motschmann

Product Committee  
(est. October 1, 2023)

Ulrich Wandschneider, Ph.D. (Chair),  
Baroness Nicola Blackwood and Helmut Jeggle

Audit Committee
Our Audit Committee for the year ended December 31, 2023, consisted 
of Anja Morawietz (Chair), Rudolf Staudigl and Ulrich Wandschneider. 
The Audit Committee assists the Supervisory Board in overseeing the 
accuracy and integrity of our financial statements, our accounting and 
financial reporting processes and audits of our financial statements, the 
effective functioning of our internal control system, our risk management 
system, our compliance with legal and regulatory requirements, our inde-
pendent auditor’s qualifications and independence, the performance of 
the independent auditor and the effective functioning of our internal audit 

functions, and, subject to certain limitations, adopts and implements perti-
nent decisions on behalf of the Supervisory Board. The Audit Committee’s 
duties and responsibilities to carry out its purpose, include, among others:

  making a recommendation to the Supervisory Board with respect to 
the proposal for the appointment of the auditors;

  considering the commissioning of the audit engagement, as well as 
the compensation, retention and oversight of the independent auditor;

  evaluating the qualifications, independence and quality of perfor-
mance of the independent auditor;

  reviewing and pre-approving the audit and non-audit services to be 
performed by the independent auditor;

  reviewing and discussing with the independent auditor and manage-
ment the annual audit plan, as well as critical accounting policies and 
practices to be used;

  discussing and determining additional areas of audit focus, as ap-
propriate; 

  reviewing and discussing with the independent auditor and man-
agement the adequacy and effectiveness of our internal accounting 
controls and critical accounting policies;

  reviewing and discussing with the independent auditor and manage-
ment the results of our annual audit;

  discussing and reviewing the sustainability report;

  reviewing the effectiveness of the compliance management system; 

  reviewing and discussing with the independent auditor and manage-
ment any quarterly or annual earnings announcements;

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

  reviewing any related party transactions and reviewing and moni-
toring potential conflict of interest situations on an ongoing basis for 
compliance with our policies and procedures; and

  overseeing procedures for the receipt, retention and treatment of 
complaints received regarding accounting, internal accounting con-
trols or auditing matters. 

Within the limits of applicable European and German law, the Audit Com-
mittee shall have the resources and authority appropriate to discharge 
its duties and responsibilities, including the authority to select, retain, 
terminate, and approve the fees and other engagement terms of spe-
cial or independent counsel, accountants or other experts and advisors, 
as it deems necessary or appropriate for so discharging its duties and 
responsibilities, without seeking approval of the Management Board or 
Supervisory Board. 

In addition, all members have the special knowledge and experience re-
quired by the German Corporate Governance Code in the field of ac-
counting and expertise in the field of auditing. This includes in particular 
knowledge and experience in applying accounting principles and internal 
control and risk management systems and specific knowledge and expe-
rience in financial statement audits. Furthermore, Ulrich Wandschneider 
and Anja Morawietz have knowledge in sustainability reporting and in 
auditing such reports.

Compensation, Nominating and Corporate Governance Committee
Our Compensation, Nominating and Corporate Governance Commit-
tee for the year ended December 31, 2023 consisted of Rudolf Staudigl 
(Chair), Nicola Blackwood (since May 25, 2023), Christoph Huber (until 
May 25, 2023) and Michael Motschmann. The Compensation, Nominat-
ing and Corporate Governance Committee’s duties and responsibilities to 
carry out its purpose include, among others:

  preparing and discussing with management policies relating to the 
remuneration of the members of our Management Board;

  reviewing and supervising corporate goals and objectives for the 
remuneration of the members of the Management Board, including 
evaluation of the performance of the members of the Management 
Board in light of these goals and proposals to the Supervisory Board 
for remuneration based on such evaluations;

  reviewing all equity-based compensation plans and arrangements 
and making recommendations to the Supervisory Board regarding 
such plans;

  assisting with identifying and recruiting candidates to fill positions on 
the Management Board and the Supervisory Board;

  considering any corporate governance issue that arises and devel-
oping appropriate recommendations for the Supervisory Board; and

  overseeing the evaluation of the Supervisory Board and reporting on 
its performance and effectiveness. 

Capital Markets Committee
Our Capital Markets Committee for the year ended December 31, 2023 
consisted of Helmut Jeggle (Chair) and Michael Motschmann. The Cap-
ital  Markets  Committee  advises  and  makes  recommendations  to  the 
Supervisory Board on issues in connection with capital measures and 
takeover, merger and acquisition activities. Its responsibilities include the 
following tasks:

  overseeing the activities of the Company relating to its capital struc-
ture and capital raising, including preparation for and implementation 
of public offerings and share issuances; and

  overseeing  the  activities  of  the  Company  relating  to  takeovers, 
mergers and acquisitions activities.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Product Committee
Our Product Committee was established as of October 1, 2023 and con-
sisted of Ulrich Wandschneider (Chair), Nicola Blackwood and Helmut 
Jeggle in the year ended December 31, 2023. The Product Committee 
advises  and  makes  recommendations  to  the  Supervisory  Board  with 
respect to our strategy and investment in research and development pro-
grams and product launch preparations including commercialization. Its 
responsibilities include the following tasks:

5.2.2 Management Board

Our Supervisory Board determines the exact number of members of our 
Management Board, which must consist of at least two members. Pursu-
ant to the Articles, the Supervisory Board may also appoint a chairperson 
or a spokesman of the Management Board. Ugur Sahin has been appoint-
ed the chair of the Management Board. 

  advising on strategy, execution and communication regarding rele-
vant go-to-market efforts; 

  overseeing  the  activities  relating  to  a)  product  development,  
b) launch plans and c) their execution; and 

Name

Prof. Ugur Sahin,  
M.D.

Term 
expires

2026

Age

58

  advising on market potential for products in clinical development. 

Jens Holstein

60

2025

Sean Marett(1)

59

2024

Sierk Poetting,  
Ph.D.

51

2026

Ryan Richardson

44

2026

James Ryan,  
Ph.D.(2)

48

2027

Prof. Özlem Türeci,  
M.D.

57

2025

Position  
(main responsibilities)

Chief Executive Officer (Research and 
Development, Scientific Collaborations, 
Patent Filings, Quality Assurance and 
Project Management)

Chief Financial Officer (Finance,  
Human Resources, Risk Management 
and Purchasing)

Chief Business Officer and Chief 
Commercial Officer (Marketing  
and Sales)

Chief Operating Officer (Production, 
IT, Laboratories and Infrastructure, 
Sustainability and Internal 
Communications)

Chief Strategy Officer (Corporate 
Strategy, Capital Market Responsibility 
and Investor Relations) 

Chief Legal Officer (Legal, Business 
Development, Alliance Management  
and Intellectual Property)

Chief Medical Officer (Clinical 
Development, Regulatory and  
Medical Affairs)

(1)   Sean Marett will retire as planned from the Management Board of BioNTech as of June 30, 2024.  

He will continue as a specialist advisor to the Company at least until the end of the year 2024.

(2)  Appointed effective as of September 1, 2023. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The members of our Management Board are appointed by our Superviso-
ry Board for a term of up to five years. They are eligible for reappointment 
or extension, including repeated reappointment and extension, after the 
completion of their term in office, in each case again for up to an additional 
five years. Under certain circumstances, such as a serious breach of duty 
or a vote of no confidence by the shareholders in a shareholders’ meeting, 
a member of the Management Board may be removed from office by our 
Supervisory Board prior to the expiration of his or her term.

The members of our Management Board conduct the daily business of 
the Company in accordance with applicable laws, our Articles of Associa-
tion and the rules of procedure for the Management Board adopted by our 
Supervisory Board. They are generally responsible for the management 
of our Company and for handling our daily business relations with third 
parties, the internal organization of our business and communications 
with our shareholders.

A member of the management board of an SE governed by German law 
may not deal with or vote on matters relating to proposals, arrangements 
or contractual agreements between himself or herself and the Compa-
ny, and a member of our Management Board may be liable to us if he or 
she has a material interest in any contractual agreement between the 
Company and a third party which is not disclosed to and approved by our 
Supervisory Board.

The rules of procedure for our Management Board provide that certain 
matters require a resolution of the entire Management Board, in addition 
to transactions for which a resolution adopted by the entire Management 
Board is required by law or required by our Articles of Association. In par-
ticular, the entire Management Board shall decide on, among others:

  the budget plan for the following year, which is to be presented by 
the Management Board to the Supervisory Board by December 20 of 
each year;

  reporting to the Supervisory Board;

  all measures and transactions that require the Supervisory Board’s 
approval;

  all measures and transactions relating to a business area that is of 
extraordinary importance or involves an extraordinary economic risk;

  establishing new lines of business or discontinuing existing ones;

  acquisitions or sales of interests or holdings; and

  certain material transactions.

The remuneration of the members of the Management Board is described 
in the remuneration report, which is prepared for the 2023 financial year 
in accordance with the requirements of Section 162 AktG and published 
on the website. 

5.3  Objectives for the Composition of the Management 

Board Pursuant to Section 76 para. 4 AktG and of the 
Supervisory Board Pursuant to Section 111 para. 5 AktG 
and Diversity Policy

Our social aspirations in our core business are complemented by good 
corporate governance. In this context, the staffing of the Management 
Board and Supervisory Board as well as long-term succession planning 
must be appropriately adapted to the needs of the Company. In addition 
to the professional and personal qualifications of the members of the 
Management Board and the Supervisory Board, we take diversity and the 
appropriate participation of women into account in the composition of 
both bodies. Furthermore, we pay attention to a balanced age structure to 
ensure long-term succession planning and have set the maximum age of 
Management Board members at 70 years and Supervisory Board mem-
bers at 80 years. The Management Board and the Supervisory Board are 
of the opinion that the current composition takes full account of the objec-
tives thus defined for the composition of these bodies. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

On March 8, 2023, the Supervisory Board set the target for the propor-
tion of women on the Management Board at 25% and on the Supervisory 
Board at 25% in accordance with Section 111 para. 5 AktG. The deadline 
by which this target is to be achieved was set at December 31, 2025. In ad-
dition, the Supervisory Board has developed a competence profile for the 
entire Board. The competence profile takes into account the following ar-
eas: general (biotech) industry experience, experience in sales and mar-
keting, management, innovation, research and development, accounting, 
auditing and controlling (including sustainability reporting), compliance, 
internal control and risk management, human resources, digitalization, 
international experience/relevant markets and CSR/sustainability. When 
making appointments to the entire Board, the Supervisory Board always 
strives to fill out this competence profile.

Özlem Türeci holds the position of Chief Medical Officer on our Manage-
ment Board, which was expanded to include James Ryan as of Septem-
ber 1, 2023 and currently has seven members. This reduced the current 
female quota of the Management Board to 14%. Nevertheless, diversity 
on the Management Board is a key topic and will be the center of efforts to 
meet the targets by December 31, 2025. 

Nicola Blackwood has been a member of our Supervisory Board since 
2023, which currently consists of six members. The current percentage 
of women on the Supervisory Board is therefore 33%, which means that 
the target of 25% was reached for the first time in the 2023 financial year. 

In accordance with Section 76 para. 4 AktG, the Management Board also 
decided on March 8, 2023 on the target number of women in manage-
ment positions. The share of women in members of the top management 
level below the Management Board and the second highest management 
level below the Management Board is to be at least 30% in each case. The 
deadline by which this target is to be achieved at both management levels 
was set at December 31, 2025.

As of December 31, 2023, a total of 37% (previous year: 38%) of the mem-
bers of the top management level below the BioNTech Management Board 
are women. At the second highest management level below the Manage-
ment Board, 46% (previous year: 40%) of the positions at BioNTech are 
held  by  women  as  of  December  31,  2023.  The  targets  were  therefore 
achieved in both the 2023 and the 2022 financial years. 

5.4 Integrity and Ethics

Compliance & Business Ethics 

BioNTech has implemented a comprehensive compliance and ethics 
program consisting of three common compliance program elements: 
Prevent – Detect – Respond.

Prevent
Policies and processes: All employees are actively informed about rele-
vant policies and guidelines. Clearly defined processes help to prevent 
business practices that do not conform to regulations or the Company’s 
values. 

Training and communication: BioNTech’s ethics and compliance rules 
are conveyed through regular training and practical supplementary ma-
terials. The training program comprises both in-person and online train-
ing sessions.

Detect
Early detection of compliance risks: In view of BioNTech’s rapid growth, 
the compliance program provides for various measures to ensure that 
potential new compliance risks are identified on a timely basis. 

Integrated controls: BioNTech’s compliance program comprises controls 
that are embedded in the relevant business processes.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Whistleblower program: The contact point for ethics protection enables 
the  anonymous  reporting  of  misconduct  of  any  kind.  Reports  can  be 
made online or in person.  

Respond
Internal  investigations:  As  soon  as  a  report  of  possible  misconduct  is 
received, a systematic review is carried out to determine whether further 
investigation is necessary. All investigations are subject to a process that 
ensures a professional, objective and confidential approach. 

Disciplinary actions and optimizations: Based on the results of investi-
gations, audits and risk assessments, the Compliance & Business Ethics 
department makes recommendations for disciplinary actions and opti-
mizations. Disciplinary actions address personal responsibilities, while 
optimizations are aimed at improving structural and procedural aspects. 

Continuous feedback: The Compliance & Business Ethics department 
systematically collects feedback from the organization in order to adapt 
the compliance program to the Company’s requirements. 

Digital Compliance Platform

The measures listed above are supported by a digital platform known as 
the BioNTech Best Practices Hub (BxP Hub). The BxP Hub offers a wide 
range of functions that support the introduction of policies, training and 
monitoring activities. Using various modules, the BxP Hub captures inter-
actions on various compliance topics, such as transfers of value to/from 
healthcare industry representatives, dinner invitations, business gifts, as 
well as potential conflicts of interest and any violations or concerns re-
ported through BioNTech’s reporting channels.

Code of Business Conduct & Ethics

The Code of Business Conduct & Ethics applies to all members of the 
Supervisory Board, members of the Management Board, managing direc-
tors of the group companies and employees of BioNTech and is available 
online at www.biontech.de. It is considered to be the fundamental basis for 
conduct when performing activities for/on behalf of BioNTech. It provides 
an overview of the general requirements that reflect compliance with 
laws, regulations and BioNTech internal policies. It covers, among other 
topics, human rights, anti-discrimination, patient safety, data protection, 
occupational safety, anti-corruption and fair competition. The Code is 
communicated to all BioNTech employees and all employees are required 
to sign that they understand and will comply. If an employee violates the 
Code of Business Conduct & Ethics, this may result in a number of dis-
ciplinary consequences, up to and including termination of employment.

Progress in 2023

In 2023, the BioNTech compliance program evolved and made significant 
progress in terms of team size, specialization and content:

General
The compliance program was refined and continued to be rolled out at 
various locations around the world. Particular attention was paid to the 
United States, where a full-time compliance employee has started to tailor 
the program to local requirements. In addition, a compliance champions 
program was launched, with local contact persons for compliance issues 
being appointed. The contact persons are local multipliers of the compli-
ance principles and serve as the first point of contact for questions and 
local requirements.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Policy Governance 
The Global Policy Governance Framework is owned by the Compliance 
& Business Ethics department and defines the central process for the 
development, approval and implementation of global and local corporate 
policies and guidelines. In 2023, 12 new policies and guidelines were 
introduced. 

Whistleblowing & Speak-Up Program
The German Whistleblower Protection Act, which came into force on 
July 2, 2023, sets out a wide range of legal requirements for whistleblower 
systems and the handling of tip-offs. Thanks to the Company’s existing 
whistleblowing system and speak-up policy, the processes were already 
largely in line with the new law, and only minor adjustments had to be 
made. 

Transparency Requirements
BioNTech complies with all legal requirements in the respective jurisdic-
tions with regard to its donations or other transfers of value in the context 
of its interactions with healthcare professionals and patient organizations. 
All the necessary information has been published on the website. In ad-
dition, in Germany BioNTech has joined the vfa (Verband Forschender 
Arzneimittelhersteller: Association of Research-Based Pharmaceuticals 
Companies) and voluntarily endorsed the FSA Code (Freiwillige Selbst-
kontrolle für die Arzneimittelindustrie e.V.) and corresponding publica-
tions in 2022.

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6 REMUNERATION REPORT

The remuneration report for the 2023 financial year is prepared in accor-
dance with the requirements of Section 162 AktG and published on the 
website at www.biontech.de. 

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

2 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

7 NON-FINANCIAL REPORT

Since our founding, we have focused on our vision and mission of im-
proving the health of people worldwide, harnessing the full potential of 
the immune system to develop drugs to fight diseases with high or unmet 
medical need.

We support the United Nations Sustainable Development Goals (SDGs). 
Our research and development work makes an important contribution 
to the United Nations’ third Sustainable Development Goal (SDG 3): To 
ensure healthy lives and promote well-being at all ages. Target 3.3 (com-
municable diseases) and Target 3.B (vaccines and medicines) are of par-
ticular significance for us. This is in line with our core commitment to glob-
al social responsibility. At the heart of our business practices is the goal 
of ensuring that people around the globe benefit from our research and 
innovations. As part of this effort, we continue to focus on urgent medical 
needs and fair and equitable access to new medicines.

Climate Strategy

We see climate protection as a core element of our commitment to sus-
tainability. If humanity does not succeed in limiting global warming to 1.5 
°C compared to pre-industrial levels, severe consequences for people 
and nature all over the world are to be expected. We therefore support the 
global agreement on climate change, or Paris Agreement adopted at the 
21st United Nations Climate Change Conference, or COP 21 at the end of 
2015 and the UN’s 13th Sustainable Development Goal (SDG 13) to take 
immediate action to address the climate crisis and its impacts.

BioNTech is addressing the climate crisis by minimizing the impact of our 
business activities and reducing greenhouse gas (GHG) emissions in 
operations and throughout the value chain. Based on the requirements of 
the Science Based Targets Initiative (SBTi) and after consultation with the 
Supervisory Board, the Management Board set binding emission reduc-
tion targets during the first quarter of 2022. For the Company’s scope 1 
and 2 GHG emissions, a target absolute reduction of 42% by 2030 (target 
amount: 1.9 kt CO₂e) compared to a 2021 baseline (3.2 kt CO₂e) was set. 
A supplier engagement target was adopted for scope 3 greenhouse gas 
emissions and further specified in the course of 2023 in accordance with 
the requirements of the SBTi: BioNTech has committed to having 72% of 
its suppliers by emissions, which comprise purchased goods and ser-
vices, capital goods and upstream transportation and distribution, to have 
set science-based SBTi targets by 2027.

The Company’s near-term and science-based emissions reduction tar-
gets for scopes 1, 2 and 3 were validated by the Science Based Targets 
Initiative in January 2024. This validation confirms that BioNTech’s scope 
1 and scope 2 climate targets are ambitious and in line with the United 
Nations Paris Climate Agreement, which aims to limit global warming to 1.5 
degrees Celsius above pre-industrial levels.

In order to achieve these climate goals, in 2023 BioNTech started to inte-
grate the targets for reducing its GHG emissions in its growth and invest-
ment planning, supply chain management and day-to-day operations. In 
September 2022, the Energy & Sustainability Projects (ESP) department 
was established for this purpose under the umbrella of the BioNTech Site 
Service unit (BSS). The new department now has six employees and its 
brief includes operationalizing the decarbonization goals in scopes 1 and 
2. In 2023, BioNTech’s Management Board also approved a multi-year 
budget to provide the ESP department with additional financial scope 
for decarbonization activities. The budget will be used for targeted mod-
ernization measures as part of the decarbonization roadmap. As an agile 
instrument, it supplements the decarbonization measures planned and 

2 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

budgeted in property conversion projects. For new buildings, the topic 
of carbon emissions was added to the budget process with a view to 
achieving the sustainability targets and complying with sustainability re-
quirements. At the same time, we continued our efforts to reduce scope 3 
emissions in our supply chain in order to achieve our supplier engagement 
target. To this  end,  discussions  with  the  key  suppliers commenced in 
2023 to agree on memoranda of understanding declaring these suppli-
ers’ intention to set science-based emissions reduction targets in accor-
dance with the SBTi. In addition, the Code of Conduct for Suppliers was 
revised in 2023 and now contains specific climate protection require-
ments for suppliers.

We are aware of the effects of the climate crisis on our business and incor-
porate this risk outlook into our holistic climate strategy. For this purpose, 
in the 2022 financial year, we analyzed and identified climate-related risks 
based on the recommendations of the Task Force on Climate-related 
Financial Disclosures (TCFD). The TCFD was founded in 2015 by the 
Financial Stability Board and has developed recommendations on how 
to mitigate the risks of climate change and make use of the opportunities 
presented. In 2022, we conducted a qualitative and quantitative scenario 
analysis covering our entire value chain and focusing on both transition 
risks and physical risks. We have started to integrate the insights from 
the analysis into our risk management and our processes. Following the 
acquisition of InstaDeep in 2023, the 2022 analysis was supplemented by 
assessments of climate-related risks at the InstaDeep locations.

Human Rights Obligations

Motivated by the Guiding Principles on Business and Human Rights ad-
opted by the United Nations in 2011 (UN Guiding Principles), many national 
action plans (NAP) for human rights due diligence in business have been 
developed worldwide. The German federal government adopted the Ger-
man NAP in 2016. This was followed by the German Act on Corporate Due 
Diligence for the Prevention of Human Rights Violations in Supply Chains, or 
the German Supply Chain Act (LkSG), which came into force on January 1, 

2023. BioNTech is monitoring the fast-moving regulatory developments 
on the topic of human rights in all countries in which the Company and 
strategic suppliers operate. 

BioNTech first pledged its commitment to the basic principles of human 
rights in 2016 on the basis of the Universal Declaration of Human Rights 
and the fundamental principles of the International Labour Organization 
(ILO). In a new edition of the 2020 Code of Business Conduct & Ethics, 
the Company has pledged its commitment to the Universal Declaration of 
Human Rights, the fundamental principles of the ILO, the Guiding Princi-
ples of the United Nations on Business and Human Rights (UNGP) and the 
ten principles of the UN Global Compact to which we became a signatory 
in 2020. Following an initial gap analysis in 2022 to assess the measures 
taken to address human rights risks, we carried out a comprehensive hu-
man rights risk assessment for the first time in 2023, covering our own op-
erations and direct suppliers. The assessment was the basis for defining 
the relevant human rights issues. As part of this process, BioNTech takes 
appropriate preventive measures to address the identified risks. We plan 
to continuously refine and adapt the human rights risk assessment and 
monitor its effectiveness. 

As of January 1, 2023, our Management Board appointed a Human Rights 
Officer as part of the Company’s preparations for the introduction of the 
German Supply Chain Act. Responsibility for human rights management 
was transferred to the Human Rights Officer. This role is responsible for all 
subsidiaries of the BioNTech Group and reports directly to the Chief Op-
erating Officer (COO), who is the member of the Management Board re-
sponsible for human rights issues. The appointment of the Human Rights 
Officer does not release the Management Board from its oversight and 
monitoring responsibility for the protection of human rights. Details on 
BioNTech’s human rights risk management in accordance with the LkSG 
can be found in the Risk Report (section 4.2) and in the BioNTech Human 
Rights Statement 2024. 

2 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

ESG Ratings

In 2023, BioNTech was able to maintain the “Prime” rating issued by the 
rating agency Institutional Shareholder Services, ISS ESG (Environmen-
tal, Social, Governance) as in 2022 and remained in the benchmark “top 
10% of the industry.” ISS ESG awarded the Company as a whole a cor-
porate rating of B- and a governance quality score of 5 (as of December 
2023) on a risk scale of 1 (low risk) to 10 (high risk).

In 2022, BioNTech was able to improve its overall S&P Global Corporate 
Sustainability Assessment (S&P CSA) score – for the first time as an ac-
tively participating company – to 32 out of 100 points compared to the 
previous year. In 2023, BioNTech scored of 45 out of 100 points and thus 
improved once again. 

The rating agency Morningstar Sustainalytics gave BioNTech an ESG risk 
rating of 24.1 in 2023 (2022: 22.3), which corresponds to a “medium risk,” 
the third of five risk levels (negligible, low, medium, high and severe). The 
rating measures the degree to which a company’s economic value is at 
risk driven by ESG factors. Sustainalytics uses absolute risk categories 
and quantitative scores from 0 to 40+ to allow a comparable assessment 
for all companies and sectors evaluated. 

CSR Management

Our CSR management, including the fields of action and the material CSR 
topics, is presented in detail in the separate 2023 Sustainability Report 
and made available online at www.biontech.de. 

With the publication of relevant and material sustainability information, we 
address all stakeholders and especially investors with high expectations 
regarding the environmental, social and governance (ESG) performance 
of companies.

2 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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2  COMBINED MANAGEMENT  
  REPORT 

  GENERAL INFORMATION 

  ECONOMIC REPORT

  MANAGEMENT REPORT 
  OF BioNTech SE

  FORECAST, OPPORTUNITY  
  AND RISK REPORT

  CORPORATE GOVERNANCE
  DECLARATION PURSUANT TO
  SECTION 315D IN CONJUNCTION
  WITH SECTION 289F HGB

  REMUNERATION REPORT

  NON-FINANCIAL REPORT

  EVENTS AFTER THE 
  REPORTING PERIOD

3  GROUP REPORT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

8  EVENTS AFTER THE  
REPORTING PERIOD

A detailed description of the events after the reporting period can be 
found in the notes to the consolidated financial statements and the annual 
financial statements of BioNTech SE. 

Mainz, March 18, 2024

BioNTech SE

Prof. Ugur Sahin, M.D. 
Chief Executive Officer

Sean Marett 
Chief Business Officer and  
Chief Commercial Officer

Ryan Richardson 
Chief Strategy Officer

Prof. Özlem Türeci, M.D. 
Chief Medical Officer

Jens Holstein 
Chief Financial Officer

Sierk Poetting, Ph.D. 
Chief Operating Officer

James Ryan, Ph.D. 
Chief Legal Officer

2 
 
 
 
 
 
 
 
 
 
 
 
 
 
A tumor consists of cancer cells that have features on 
the surface that are not typical for healthy cells. Immune 
cells can be taught and equipped to recognize these 
features and orchestrate the elimination of the cancer.

115

GROUP  

REPORT 2023 3

BioNTech | Annual Report 2023BioNTech | Annual Report 2023

116

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

CONSOLIDATED STATEMENTS OF PROFIT OR LOSS

(in millions €, except per share data)

Note

2023

2022

2021

Years ended December 31, 

Revenues

Commercial revenues

Research & development revenues

Total revenues

Cost of sales

Research and development expenses

Sales and marketing expenses

General and administrative expenses (1)

Other operating expenses (1)

Other operating income 

Operating income

Finance income

Finance expenses

Profit before tax

Income taxes

Profit for the period

Earnings per share

Basic earnings for the period per share

Diluted earnings for the period per share

6

6

7.1

7.1

7.1

7.1

7.2

7.3

7.4

7.5

8

9

9

3,815.5

3.5

3,819.0

(599.8)

(1,783.1)

(62.7)

(495.0)

(293.0)

105.0

690.4

519.6

(23.9)

1,186.1

(255.8)

930.3

3.87

3.83

17,194.6

116.0

17,310.6

(2,995.0)

(1,537.0)

(59.5)

(481.7)

(410.0)

815.3

12,642.7

330.3

(18.9)

12,954.1

(3,519.7)

9,434.4

38.78

37.77

18,874.0

102.7

18,976.7

(2,911.5)

(949.2)

(50.4)

(276.8)

(103.4)

598.4

15,283.8

67.7

(305.1)

15,046.4

(4,753.9)

10,292.5

42.18

39.63

(1)  Adjustments to prior-year figures due to change in functional allocation of general and administrative 

expenses and other operating expenses (see Note 7.2).

The accompanying notes form an integral part of these consolidated financial statements.

3 
 
 
 
 
 
 
 
 
 
 
 
 
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2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME

(in millions €)

Profit for the period

Other comprehensive income

Other comprehensive income that may be reclassified to profit  
or loss in subsequent periods, net of tax

Exchange differences on translation of foreign operations

Net other comprehensive income/(loss) that may be reclassified  
to profit or loss in subsequent periods 

Other comprehensive loss that will not be reclassified to profit  
or loss in subsequent periods, net of tax

Net gain on equity instruments designated at fair value through  
other comprehensive income

Remeasurement gain on defined benefit plans

Net other comprehensive income that will not be reclassified  
to profit or loss in subsequent periods

Other comprehensive income/(loss) for the period, net of tax 

Comprehensive income for the period, net of tax

Note

Years ended December 31,

2022

9,434.4

2021

10,292.5

11.2

11.2

10.5

0.6

11.1

22.3

8.4

8.4

—

0.3

0.3

8.7

9,456.7

10,301.2

2023

930.3

(19.8)

(19.8)

3.7

0.3

4.0

(15.8)

914.5

The accompanying notes form an integral part of these consolidated financial statements.

3 
 
 
 
 
 
 
 
 
 
 
 
 
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2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

CONSOLIDATED STATEMENTS OF FINANCIAL POSITION

(in millions €)

Assets

Non-current assets 

Goodwill

Other intangible assets 

Property, plant and equipment 

Right-of-use assets

Other financial assets

Other non-financial assets

Deferred tax assets 

Total non-current assets 

Current assets

Inventories 

Trade and other receivables 

Contract assets 

Other financial assets 

Other non-financial assets

Income tax assets 

Cash and cash equivalents

Total current assets 

Total assets

Note

December 31, 2023

December 31, 2022

10

10

11

20

12

14

8

13

12

6

12

14

8

12

362.5

804.1

757.2

214.4

1,176.1

83.4

81.3

3,479.0

357.7

2,155.7

4.9

4,885.3

280.9

179.1

11,663.7

19,527.3

23,006.3

61.2

158.5

609.2

211.9

80.2

6.5

229.6

1,357.1

439.6

7,145.6

—

189.4

271.9

0.4

13,875.1

21,922.0

23,279.1

The accompanying notes form an integral part of these consolidated financial statements.

Continued on next page

3 
 
 
 
 
 
 
 
 
 
 
 
 
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119

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

CONSOLIDATED STATEMENTS OF FINANCIAL POSITION

(in millions €)

Equity and liabilities

Equity 

Share capital

Capital reserve

Treasury shares

Retained earnings

Other reserves 

Total equity 

Non-current liabilities 

Lease liabilities, loans and borrowings

Other financial liabilities 

Income tax liabilities

Provisions

Contract liabilities

Other non-financial liabilities

Deferred tax liabilities

Total non-current liabilities 

Current liabilities 

Lease liabilities, loans and borrowings

Trade payables and other payables

Other financial liabilities 

Refund liabilities

Income tax liabilities

Provisions

Contract liabilities

Other non-financial liabilities

Total current liabilities

Total liabilities 

Total equity and liabilities 

The accompanying notes form an integral part of these consolidated financial statements.

Note

December 31, 2023

December 31, 2022

15

15

15

16

12

12

8

17

6

19

8

12

12

12

6

8

17

6

19

248.6

1,229.4

(10.8)

19,763.3

(984.6)

20,245.9

191.0

38.8

—

8.8

398.5

13.1

39.7

689.9

28.1

354.0

415.2

—

525.5

269.3

353.3

125.1

2,070.5

2,760.4

23,006.3

248.6

1,828.2

(5.3)

18,833.0

(848.9)

20,055.6

176.2

6.1

10.4

8.6

48.4

17.0

6.2

272.9

36.0

204.1

785.1

24.4

595.9

367.2

77.1

860.8

2,950.6

3,223.5

23,279.1

3 
 
 
 
 
 
 
 
 
 
 
 
 
1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

BioNTech | Annual Report 2023

120

CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS’ EQUITY

Equity attributable to equity holders of the parent

Note

Share  
capital

246.3

Capital  
reserve

1,514.5

Treasury  
shares

(4.8)

(in millions €)

As of January 1, 2021

Profit for the period

Other comprehensive income

Total comprehensive income

Issuance of treasury shares

Transaction costs

Share-based payments 

As of December 31, 2021

Profit for the period

Other comprehensive income

Total comprehensive income

Issuance of share capital

Redemption of convertible note

Share repurchase program

Transaction costs

Dividends

Share-based payments

Deferred taxes

As of December 31, 2022

Profit for the period

Other comprehensive loss

Total comprehensive profit/(loss)

Share repurchase program

Share-based payments

Current and deferred taxes

Treasury shares used for acquisition  
of business combination

As of December 31, 2023

—

—

—

—

—

—

—

—

—

162.6

(2.7)

—

—

—

—

1.0

—

—

246.3

1,674.4

(3.8)

—

—

—

0.5

1.8

—

—

—

—

—

—

—

—

67.1

233.2

(979.5)

(0.1)

—

833.1

—

—

—

—

—

—

(6.9)

—

—

5.4

—

Retained 
earnings

(409.6)

10,292.5

—

10,292.5

—

—

—

9,882.9

9,434.4

—

9,434.4

—

—

—

—

(484.3)

—

—

Other  
reserves 

25.4

—

8.7

8.7

—

—

59.8

93.9

—

22.3

22.3

—

—

—

—

—

(1,519.8)

554.7

Total  
equity 

1,371.8

10,292.5

8.7

10,301.2

163.6

(2.7)

59.8

11,893.7

9,434.4

22.3

9,456.7

67.6

235.0

(986.4)

(0.1)

(484.3)

(681.3)

554.7

248.6

1,828.2

(5.3)

18,833.0

(848.9)

20,055.6

—

—

—

—

—

—

—

248.6

—

—

—

(731.6)

30.2

—

102.6

1,229.4

—

—

—

(6.9)

0.3

—

1.1

930.3

—

930.3

—

—

—

—

—

(15.8)

(15.8)

—

(15.1)

(104.8)

930.3

(15.8)

914.5

(738.5)

15.4

(104.8)

—

103.7

(10.8)

19,763.3

(984.6)

20,245.9

15

16

15

12

15

15

16

8

15

16

8

5

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

CONSOLIDATED STATEMENTS OF CASH FLOWS

(in millions €)

Operating activities

Profit for the period

Income taxes

Profit before tax

Adjustments to reconcile profit before tax to net cash flows

  Depreciation and amortization of property, plant, equipment, intangible assets and right-of-use assets

  Share-based payment expenses

  Net foreign exchange differences

  Loss on disposal of property, plant and equipment

  Finance income excluding foreign exchange differences

  Finance expense excluding foreign exchange differences

  Movements in government grants

  Other non-cash income/(loss)

  Net (gain)/loss on derivative instruments at fair value through profit or loss

Working capital adjustments

  Decrease/(increase) in trade and other receivables, contract assets and other assets

  Decrease/(increase) in inventories

 Increase in trade payables, other financial liabilities, other liabilities, contract liabilities,  
refund liabilities and provisions

Interest received and realized gains from cash and cash equivalents

Interest paid and realized losses from cash and cash equivalents

Income tax paid

Share-based payments

Net cash flows from operating activities

Years ended December 31, 

2022

2021

9,434.4

3,519.7

12,954.1

123.3

108.6

625.5

0.6

(265.3)

18.9

0.3

—

(241.0)

4,369.9

62.9

85.7

29.3

(21.5)

(4,222.1)

(51.8)

13,577.4

10,292.5

4,753.9

15,046.4

75.2

93.9

(387.5)

4.6

(1.5)

305.2

(89.0)

(2.2)

57.3

(11,808.1)

(438.4)

1,516.1

1.2

(12.2)

(3,457.9)

(13.4)

889.7

2023

930.3

255.8

1,186.1

183.4

51.4

(298.0)

3.8

(519.6)

7.9

2.4

—

175.5

5,374.0

81.9

118.9

258.2

(5.4)

(482.9)

(766.2)

5,371.4

The accompanying notes form an integral part of these consolidated financial statements.

Continued on next page

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

CONSOLIDATED STATEMENTS OF CASH FLOWS

(in millions €)

Investing activities

Purchase of property, plant and equipment

Proceeds from sale of property, plant and equipment

Purchase of intangible assets and right-of-use assets

Acquisition of subsidiaries and businesses, net of cash acquired

Investment in other financial assets

Proceeds from maturity of other financial assets

Net cash flows used in investing activities

Financing activities

Proceeds from issuance of share capital and treasury shares, net of costs

Proceeds from loans and borrowings

Repayment of loans and borrowings

Payments related to lease liabilities

Share repurchase program

Dividends

Net cash flows from/ (used in) financing activities

Net increase/(decrease) in cash and cash equivalents

Change in cash and cash equivalents resulting from exchange rate differences

Change in cash and cash equivalents resulting from other valuation effects

Cash and cash equivalents at the beginning of the period

Cash and cash equivalents as of December 31

The accompanying notes form an integral part of these consolidated financial statements.

Years ended December 31,

2023

2022

2021

(249.4)

(0.7)

(455.4)

(336.9)

(7,128.4)

1,216.3

(6,954.5)

—

0.3

(0.1)

(40.3)

(738.5)

—

(778.6)

(2,361.7)

(14.5)

164.8

13,875.1

11,663.7

(329.2)

0.6

(34.1)

—

(47.8)

375.2

(35.3)

110.5

0.8

(18.8)

(41.1)

(986.4)

(484.3)

(1,419.3)

12,122.8

60.1

(0.5)

1,692.7

13,875.1

(127.5)

3.4

(26.5)

(20.8)

(19.5)

(375.2)

(566.1)

160.9

—

(52.6)

(14.1)

—

—

94.2

417.8

64.7

—

1,210.2

1,692.7

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

NOTES TO THE CONSOLIDATED  
FINANCIAL STATEMENTS

1 CORPORATE INFORMATION

BioNTech  SE  is  a  limited  company  incorporated  and  domiciled  in  
Germany. American Depositary Shares (ADS) representing BioNTech 
SE’s ordinary shares have been publicly traded on the Nasdaq Global 
Select Market since October 10, 2019. The registered office is located 
in Mainz, Germany (An der Goldgrube 12, 55131 Mainz). BioNTech SE is 
registered in the commercial register B of the Mainz Local Court under the 
number HRB 48720. These consolidated financial statements have been 
prepared in accordance with International Financial Reporting Standards 
(IFRS) as endorsed by the European Union (EU), and give a true and fair 
view of the financial position and results of operations of the Group in  
accordance with International Financial Reporting Standards (IFRS) and 
the results of operation of BioNTech SE and its subsidiaries, hereinafter 
also referred to as “BioNTech”, the “Group”, “we” or “us”. 

Our consolidated financial statements for the year ended December 31, 
2023, were prepared by the Management Board on March 18, 2024.

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

2  SIGNIFICANT ACCOUNTING  

2.2 Basis of Consolidation

POLICIES

2.1 Basis of Preparation

General

The consolidated financial statements comprise the financial statements 
of BioNTech SE and its controlled investees (subsidiaries). 

The Group controls an investee if, and only if, the Group has

  power over the investee (i.e., existing rights that give it the current 
ability to direct the relevant activities of the investee); 

  exposure, or rights, to variable returns from its involvement with the 
investee; and 

  the ability to use its power over the investee to affect its returns. 

The  consolidated  financial  statements  have  been  prepared  in  accor-
dance with the International Financial Reporting Standards (IFRS) as 
issued by the International Accounting Standards Board (IASB). 

Generally, there is a presumption that a majority of voting rights results in 
control. 

We prepare and publish our consolidated financial statements in Euros 
and  round  numbers  to  thousands  or  millions  of  Euros,  respectively.  
Accordingly, numerical figures shown as totals in some tables may not 
be exact arithmetic aggregations of the figures that preceded them and 
figures presented in the explanatory notes may not add up to the rounded 
arithmetic aggregations. Rounding applied may differ from rounding pub-
lished in different units in the previous years. 

Segment Information

Decisions with respect to business operations and resource allocations 
are made by our Management Board, as the chief operating decision maker  
(CODM) based on BioNTech as a whole. Accordingly, we operate and 
make decisions as a single operating segment, which is also our reporting 
segment. 

Whether an investee is controlled is re-assessed if facts and circumstances  
indicate that there are changes to one or more of the three elements of 
control. Consolidation of a subsidiary begins when control is obtained 
over the subsidiary and ceases when control over the subsidiary is lost. 

The profit/(loss) and each component of other comprehensive income/
(loss) for the period are attributed to the equity holders of the parent 
of  the  Group  and  to  the  non-controlling  interests,  even  if  this  results 
in the non-controlling interests having a deficit balance. When neces-
sary, adjustments are made to the consolidated financial statements of  
subsidiaries  to  bring  their  accounting  policies  in  line  with  the  Group’s 
accounting policies. All intra-group assets and liabilities, equity, income, 
expenses and cash flows relating to transactions between members of 
the Group are eliminated on consolidation.

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

A change in the ownership interest of a subsidiary, without a loss of con-
trol, is accounted for as an equity transaction. 

If control over a subsidiary is lost, the related assets (including goodwill), 
liabilities, non-controlling interests and other components of equity are 
derecognized, while any resultant gain or loss is recognized in the consol-
idated statements of profit or loss. Any investment retained is recognized 
at fair value.

In determining the spot exchange rate to use on initial recognition of the 
related asset, expense or income (or part of it) on the derecognition of a 
non-monetary asset or non-monetary liability relating to advance consid-
eration, the date of the transaction is the date on which the Group initially 
recognizes the non-monetary asset or non-monetary liability arising from 
the advance consideration. If there are multiple payments or receipts in 
advance, the Group determines the transaction date for each payment or 
receipt of advance consideration.

2.3 Summary of Material Accounting Policies

2.3.1 Foreign Currencies

Our  consolidated  financial  statements  are  presented  in  Euros,  which 
is also our functional currency. For each entity, the Group determines 
the functional currency, and items included in the consolidated financial 
statements of such entities are measured using that functional currency. 
We use the direct method of consolidation and, on disposal of a foreign  
operation, the gain or loss that is reclassified to the consolidated statements 
of profit or loss reflects the amount that arises from using this method.

Transactions and Balances
Transactions in foreign currencies are initially recorded by the Group’s 
entities at their respective functional currency spot rates at the date the 
transaction first qualifies for recognition.

Foreign Currency Translation
Foreign currency translation effects from the translation of operating 
activities include foreign exchange differences arising on operating items 
such as trade receivables and trade payables and are either shown as 
other operating income or expenses on a cumulative basis. Foreign cur-
rency translation effects presented within finance income and expenses 
include foreign exchange differences arising on financing items such as 
loans and borrowings as well as foreign exchange differences arising on 
cash and cash equivalents and are either shown as finance income or 
expenses on a cumulative basis. 

Foreign Currency Translation on Consolidation
Upon consolidation, the assets and liabilities of foreign operations are 
translated into Euros at the rate of exchange prevailing at the reporting 
date and the transactions recorded in their consolidated statements of 
profit or loss are translated at exchange rates prevailing at the dates of the 
transactions.

Monetary assets and liabilities denominated in foreign currencies are 
translated at the functional currency spot rates of exchange at the report-
ing date.

The exchange differences arising on translation for consolidation are 
recognized  in  other  comprehensive  income.  On  disposal  of  a  foreign 
operation, the component of other comprehensive income relating to that 
particular foreign operation is reclassified to profit or loss.

Non-monetary items that are measured in terms of historical cost in a 
foreign currency are translated using the exchange rates at the dates of 
the initial transactions.

Any goodwill arising on the acquisition of a foreign operation and any fair 
value adjustments to the carrying amounts of assets and liabilities arising 
upon the acquisition are treated as assets and liabilities of the foreign  
operation and translated at the spot rate of exchange at the reporting date.

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Identification of Performance Obligations
Our customer contracts often include bundles of licenses, goods and 
services. If the granting of a license is bundled together with delivering 
of goods and or the rendering of services, it is assessed whether these 
agreements are comprised of more than one performance obligation. A 
performance obligation is only accounted for as the grant of a license if 
the grant of a license is the sole or the predominant promise of the perfor-
mance obligation. 

Determining Transaction Prices
We apply judgment when determining the consideration that is expected 
to be received. If the consideration in an agreement includes a variable 
amount, we estimate the amount of consideration to which we will be en-
titled in exchange for transferring the goods to the customer. At contract 
inception, the variable consideration is estimated based on the most likely 
amount of consideration expected from the transaction and constrained 
until it is highly probable that a significant revenues reversal in the amount 
of cumulative revenues recognized will not occur when the associated 
uncertainty with respect to the variable consideration is subsequently 
resolved. The estimated revenues are updated at each reporting date to 
reflect the current facts and circumstances.

Allocation of Transaction Prices
If a contract with a customer contains more than one performance obli-
gation, the transaction price is allocated to each performance obligation 
based on relative standalone selling prices. We have established the fol-
lowing hierarchy to determine the standalone selling prices.

2.3.2 Current versus Non-Current Classifications

Assets and liabilities in the consolidated statements of financial position 
are presented based on current or non-current classification. 

An asset is current when it is either: (i) expected to be realized or intended 
to be sold or consumed in the normal operating cycle, (ii) held primar-
ily for the purpose of trading, (iii) expected to be realized within twelve 
months after the reporting period, or (iv) cash or cash equivalents, unless 
it is restricted from being exchanged or used to settle a liability for at least 
twelve months after the reporting period. All other assets are classified as 
non-current. 

A liability is current when it is either: (i) expected to be settled in the normal 
operating cycle, (ii) held primarily for the purpose of trading, (iii) due to be 
settled within twelve months after the reporting period, or (iv) there is no 
unconditional right to defer the settlement of the liability for at least twelve 
months after the reporting period. The terms of the liability that could, at 
the option of the counterparty, result in its settlement by the issue of equi-
ty instruments do not affect its classification. The Group classifies all other 
liabilities as non-current. 

Deferred tax assets and liabilities are classified as non-current assets and 
liabilities, respectively.

2.3.3 Revenue from Contracts with Customers

Revenue
Identification of the Contract
We generate revenues from collaboration and license agreements, which 
contain multiple elements, including licenses to use, research, develop, 
manufacture and commercialize candidates and products, research and 
development services as well as obligations to develop and manufacture 
preclinical and clinical material and products. We determined that those 
collaboration and license agreements qualify as contracts with custom-
ers. A contract is an agreement between two or more parties that estab-
lishes enforceable rights and obligations. 

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

  Where standalone selling prices for offered licenses, goods or ser-
vices are observable and reasonably consistent across customers, 
our standalone selling price estimates are derived from our respective 
pricing history. However, due to the limited number of customers and 
the limited company history, this approach can rarely be used.

  Where  sales  prices  for  an  offering  are  not  directly  observable  
or  highly  variable  across  customers,  we  follow  a  cost-plus-margin  
approach.

  For  offerings  that  have  highly  variable  pricing  and  lack  substan-
tial direct costs to estimate based on a cost-plus-margin approach,  
we allocate the transaction price by applying a residual approach.

Revenue arrangements that involve two or more partners who contribute 
to the provision of a specific good or service to a customer are assessed 
in terms of principal-agent considerations in order to determine the ap-
propriate treatment for the transactions between us and the collaborator 
and the transactions between us and other third parties. The classifica-
tion of transactions under such arrangements is determined based on the 
nature and contractual terms of the arrangement along with the nature of 
the operations of the participants. Any consideration related to activities 
in which we are considered the principal, which includes being in control 
of the good or service before such good or service is transferred to the 
customer, is accounted for as gross revenues. Any consideration related 
to activities in which we are considered the agent is accounted for as net 
revenues.

Judgment is required when estimating standalone selling prices.

Recognition of Revenues
For each separate performance obligation, it is evaluated whether con-
trol is transferred either at a point in time or over time. For performance 
obligations that are satisfied over time, revenues are recognized based 
on a measure of progress, which depicts the performance in transferring 
control to the customer. Under the terms of our licensing arrangements, 
we provide the licensee with a research and development license, which 
represents a right to access our intellectual property as it exists through-
out the license period (as our intellectual property is still subject to further 
research). Therefore, the promise to grant a license is accounted for as a 
performance obligation satisfied over time as our customers simultane-
ously receive and consume the benefits from our performance. 

Revenues  based  on  the  collaboration  partners’  gross  profit,  which  is 
shared under the respective collaboration agreements, are recognized 
based on the sales-based or usage-based royalty exemption; i.e., when 
the underlying sales occur, which is when the performance obligation has 
been satisfied. As described further in Note 3, judgment is applied to cer-
tain aspects when accounting for the collaboration agreements.

Revenues from the sale of pharmaceutical and medical products (e.g., 
COVID-19 vaccine sales and other sales of peptides and retroviral vectors 
for clinical supply) are recognized when we transfer control of the product 
to the customer. Control of the product normally transfers when the cus-
tomer gains physical possession and we have not retained any significant 
risks of ownership or future obligations with respect to the product. In 
general, payments from customers are due within 30 days after invoice. 
However, with respect to our collaboration with Pfizer Inc., or Pfizer, there 
is a significant time lag between when revenues are recognized and the 
payments are received. The contractual settlement of the gross profit 
share has a temporal offset of more than one calendar quarter. As Pfizer’s 
financial quarter for subsidiaries outside the United States differs from 
ours, it creates an additional time lag between the recognition of revenues 
and the payment receipt. 

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

For certain contracts, the finished product may temporarily be stored at 
our location under a bill-and-hold arrangement. Revenues from bill-and-
hold  arrangements  are  recognized  at  the  point  in  time  when  the  cus-
tomer obtains control of the product and all of the following criteria have 
been met: (i) the arrangement is substantive; (ii) the product is identified 
separately  as  belonging  to  the  customer;  (iii)  the  product  is  ready  for 
physical transfer to the customer; and (iv) we do not have the ability to 
use the product or direct it to another customer. In determining when the 
customer obtains control of the product, we consider certain indicators, 
including whether title and significant risks and rewards of ownership 
have transferred to the customer and whether customer acceptance has 
been received. 

Contract Balances
Contract Assets
A contract asset is the right to consideration in exchange for goods or 
services transferred to the customer. If we transfer goods or services to 
a customer before the customer pays the respective consideration or 
before payment is due, a contract asset is recognized for the earned con-
sideration that is conditional.

Trade Receivables
A receivable represents our right to an amount of consideration that is 
unconditional (i.e., only the passage of time is required before payment of 
the consideration is due). 

Contract Liabilities
A contract liability is the obligation to transfer goods or services to a cus-
tomer for which we have received consideration (or an amount of consid-
eration is due) from the customer. If a customer pays consideration before 
we transfer goods or services to the customer, a contract liability is recog-
nized when the payment is made or when the payment is due (whichever 
is earlier). Contract liabilities are recognized as revenue when we fulfill our 
performance obligations under the contract.

Refund Liabilities
A refund liability is a consideration which has been received but which 
will need to be refunded to the customer in the future as it represents 
an amount to which we are ultimately not entitled under the contract. A 
refund liability is measured at the amount of consideration received (or 
receivable) to which we do not expect to be entitled (i.e., amounts not 
included in the transaction price). We update our estimates of refund lia-
bilities (and the corresponding change in the transaction price) at the end 
of each reporting period.

2.3.4 Research and Development Expenses

Research and development costs are expensed in the period in which 
they are incurred. Regarding internal projects, we consider that regula-
tory approval and other uncertainties inherent in the development of new 
products preclude the capitalization of internal development expenses as 
an intangible asset until marketing approval from a regulatory authority is 
obtained. Payments made to third parties, such as contract research and 
development organizations as compensation for subcontracted research 
and development, that are deemed not to transfer intellectual property 
are  expensed  as  internal  research  and  development  expenses  in  the 
period in which they are incurred. Such payments are only capitalized 
if they meet the criteria for recognition of an internally generated intan-
gible asset, usually when marketing approval has been received from a 
regulatory authority. We have entered into agreements under which third 
parties grant licenses to us, which are known as in-license agreements. 
If in-licensing results in consideration for the acquisition of intellectual 
property that meets the definition of an identifiable asset, this is capital-
ized as an intangible asset unless the respective intellectual property is 
mainly used as part of our general ongoing research and development 
activities without any intent to market the respective product as such.  
If the transaction also includes research and development services to be 
provided by the licensor, the share of consideration attributable to these 
services is recognized in research and development expenses in line with 
the performance of the services. Sales-based milestone or royalty pay-
ments incurred under license agreements after the approval date of the 
respective pharmaceutical product are recognized as expenses in cost 
of sales as incurred.

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Subsequent internal research and development costs in relation to intel-
lectual property rights are expensed because the technical feasibility of 
the internal research and development activity can only be demonstrated 
by the receipt of marketing approval for a related product from a regulato-
ry authority in a major market. 

Prior  to  the  second  quarter  of  2023,  we  had  assessed  that  inventory 
produced prior to successful regulatory approval did not meet the criteria 
for capitalization as an asset, and accordingly expensed the costs of pre-
launch inventory as research and development costs. Based on the expe-
rience of the past years and the developments since our COVID-19 vac-
cine was first authorized or approved for emergency or temporary use, 
our assessment regarding the potential to produce economic benefits 
changed. Beginning with the second quarter of 2023, pre-launch products  
from the Comirnaty product family with their potential for economic ben-
efit fulfill the recognition criteria for an asset under the IFRS Conceptual 
Framework. At each reporting date, the respective inventory is measured 
at the lower of cost and net realizable value. However, because it is not 
probable until regulatory approval is obtained, we consider the net realiz-
able value to be zero, as this is the probable amount expected to be real-
ized from its sale until approval is obtained. The write-down is recognized 
in the statements of profit or loss as research and development expenses. 
If regulatory approval for a product candidate is obtained, the relevant 
write-down would be reversed to a maximum of the original cost. Subse-
quently, inventory is recognized as cost of sales. This reassessment has 
been treated as a change in estimate and the impacts on current period 
inventories, cost of sales and research and development expenses are 
described in Note 7.1.

2.3.5 Government Grants

Government grants and similar grants which are accounted for in accor-
dance with IAS 20 are recognized where there is reasonable assurance 
that the grant will be received and all attached conditions will be complied 
with. When the grant relates to an expense item, it is recognized as other 
income on a systematic basis over the periods that the related costs for 
which the grant is intended to compensate are expensed. When the grant 
relates to an asset, it is recognized as deferred income within the con-
solidated statements of financial position. Other income is subsequently 
recognized in our consolidated statements of profit or loss over the useful 
life of the underlying asset subject to funding. 

2.3.6 Taxes

Current Income Tax
Current income tax assets and liabilities are measured at the amount 
expected to be recovered from or paid to the taxation authorities. The tax 
rates and tax laws used to compute the amount are those that are enact-
ed or substantively enacted at the reporting date in the countries where 
the Group operates and generates taxable income. 

In addition, current income taxes presented for the period include adjust-
ments for uncertain tax payments or tax refunds for periods not yet finally 
assessed by tax authorities, excluding interest expenses and penalties 
on the underpayment of taxes. In the event that amounts included in the 
tax return are considered unlikely to be accepted by the tax authorities  
(uncertain tax positions), a provision for income taxes is recognized. 

Management periodically evaluates positions taken in the tax returns with 
respect to situations in which applicable tax regulations are subject to 
interpretation and establishes provisions where appropriate.

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Deferred Tax
Deferred tax is provided using the liability method on temporary differences 
between the tax bases of assets and liabilities and their carrying amounts 
for financial reporting purposes at the reporting date.

Deferred tax assets and liabilities are measured at the tax rates that are 
expected to apply in the year in which the asset is realized, or the liability 
is settled, based on tax rates (and tax laws) that have been enacted or 
substantively enacted at the reporting date. 

Deferred tax liabilities are recognized for all taxable temporary differences, 
except: 

Unrecognized deferred tax assets are re-assessed at each reporting date 
and are recognized to the extent that it has become probable that future 
taxable profits will allow the deferred tax asset to be recovered. 

Recognition of Taxes
Current and deferred tax items are recognized similarly to the underlying 
transaction either in profit or loss, other comprehensive income or directly 
in equity.

Current tax assets and current tax liabilities are offset if, and only if, we 
have a legally enforceable right to set off the recognized amounts and 
intend either to settle on a net basis, or to realize the asset and settle the 
liability simultaneously. Deferred tax assets and deferred tax liabilities are 
only offset when we have a legally enforceable right to set off current tax 
assets and current tax liabilities and the deferred tax assets and deferred 
tax liabilities relate to income taxes levied by the same taxation authority 
on either (i) the same taxable entity or (ii) different taxable entities, which 
intend either to settle current tax liabilities and assets on a net basis, or to 
realize the assets and settle the liabilities simultaneously, in each future 
period in which significant amounts of deferred tax liabilities or assets are 
expected to be settled or recovered.

  when the deferred tax liability arises from the initial recognition of 
goodwill or an asset or liability in a transaction that is not a business 
combination and, at the time of the transaction, affects neither the  
accounting profit nor taxable profit or loss; or 

  in respect of taxable temporary differences associated with invest-
ments in subsidiaries, when the timing of the reversal of the temporary 
differences can be controlled and it is probable that the temporary 
differences will not reverse in the foreseeable future. 

Deferred tax assets are recognized for all deductible temporary differ-
ences, the carry forward of unused tax credits and any unused tax losses. 
Deferred tax assets are recognized to the extent that it is probable that 
taxable profit will be available against which the deductible temporary dif-
ferences, the carry forward of unused tax credits and unused tax losses 
can be utilized, except:

  when the deferred tax asset relating to the deductible temporary 
difference arises from the initial recognition of an asset or liability in a 
transaction that is not a business combination and, at the time of the 
transaction, affects neither the accounting profit nor taxable profit or 
loss; or

  in respect of deductible temporary differences associated with in-
vestments in subsidiaries, deferred tax assets are recognized only to 
the extent that it is probable that the temporary differences will reverse 
in the foreseeable future and taxable profit will be available against 
which the temporary differences can be utilized. 

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Sales Tax
Expenses and assets are recognized net of sales tax, except when the 
sales tax incurred on a purchase of assets or services is not recoverable 
from the taxation authority.

entities which are part of the Group, beginning in financial year 2024. The 
Group falls within the scope of these regulations. The Group carried out 
an analysis as of the reporting date to determine the fundamental impact 
and the jurisdictions in which the Group is exposed to possible effects in 
connection with a Pillar 2 top-up tax.

The net amount of sales tax recoverable from, or payable to, the taxation 
authority is included as part of receivables or payables in the consolidated 
statements of financial position.

Future Tax Legislation
Based on the Organisation for Economic Co-operation and Development 
(OECD) Base Erosion and Profit Shifting (BEPS) project to tackle tax 
avoidance, the OECD/G20 Inclusive Framework (an association of about 
140 countries) decided to introduce a global minimum taxation for large 
multinational groups (known as Pillar 2). The Global Anti-Base Erosion 
Rules are intended to ensure that large multinational groups pay a min-
imum level of tax on the income arising in each jurisdiction where they 
operate. In December 2021, the OECD published its Model Rules, which 
serve as a draft bill for implementation into national domestic law, followed 
by guidelines and commentaries published in March 2022. In December 
2022, the EU adopted a corresponding directive (EU 2022/2523) that 
obliges EU member states to transpose the rules into national domestic 
law. If the effective tax rate in any jurisdiction is below the minimum rate 
(15%), the Group may be subject to the so-called top-up tax or a so-called 
qualified domestic minimum top-up tax. 

Based on this analysis, no countries were identified in which the Group 
would be materially affected by a Pillar 2 top-up tax. Consequently, the 
average effective Group tax rate would not have changed if the Pillar 2 
legislation had already been in force on the balance sheet date. BioNTech 
applies the exception in IAS 12, according to which no deferred tax assets 
and liabilities in connection with the second income taxes of the second 
pillar of the OECD are recognized and no disclosures are made. 

2.3.7 Business Combinations and Goodwill

Business combinations are accounted for using the acquisition method. 
The cost of an acquisition is measured as the aggregate of the consider-
ation transferred, which is measured at acquisition date fair value, and the 
amount of any non-controlling interests in the acquiree.

Goodwill is initially measured at cost as the excess of the aggregate of the 
consideration transferred and the amount recognized for non-controlling 
interests and any previous interest held over the net identifiable assets 
acquired and liabilities assumed.

Several jurisdictions in which the Group operates have transposed the 
OECD Model Rules into national domestic law and brought them into 
force. In addition, the Group is closely following the progress of the legis-
lative process in each country in which the Group operates. As of the bal-
ance sheet date, the BEPS Pillar 2 regulations (MinBestRL UmsG) had al-
ready been transposed into German law (MinStG). The date of application 
of the law in Germany is for financial years beginning after December 30, 
2023. Subsequently, as the OECD Model Rules have entered into force in 
Germany, the Group is obliged to file top-up tax information returns for all 

Costs related to executing business combinations are recognized when 
they are incurred and are classified as general and administrative expenses. 

After initial recognition, goodwill is tested at least annually or when there 
is an indication for impairment. See Note 2.3.10. For the purpose of im-
pairment testing, goodwill acquired in a business combination is, from the 
acquisition date, allocated to each of the cash-generating units that are 
expected to benefit from the combination, irrespective of whether other 
assets or liabilities of the acquiree are assigned to those units. 

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Where goodwill has been allocated to a cash-generating unit (CGU) and 
part of the operation within that unit is disposed of, the goodwill associ-
ated with the operation disposed of is included in the carrying amount of 
the operation when determining the gain or loss on disposal. Goodwill dis-
posed of in these circumstances is measured based on the relative values 
of the operation disposed of and the portion of the cash-generating unit 
retained.

2.3.8 Intangible Assets

Intangible assets acquired separately are measured on initial recognition 
at cost. The cost of intangible assets acquired in a business combination 
is their fair value at the date of acquisition. Following initial recognition,  
intangible assets are carried at cost less any accumulated amortization 
and accumulated impairment losses.

The portion of the consideration in in-licensing agreements paid by us 
to acquire intellectual property is recognized as an intangible asset. If 
in-licensing includes research and development services, the share of 
consideration attributable to these services is deferred and recognized in 
research and development expenses according to the utilization thereof. 
Payments depending on the achievement of specific milestones as part of 
the purchase of intangible assets, except for intangible assets acquired 
in  a  business  combination,  are  recognized  as  subsequent  acquisition 
cost of the intangible asset and as a financial liability once the milestone 
is reached.

The useful lives of intangible assets are assessed as either finite or indef-
inite. 

Intangible assets with finite lives are amortized generally on a straight-line 
basis over the useful life and assessed for impairment whenever there is 
an indication that the intangible asset may be impaired. The amortization 
period and the amortization method for an intangible asset with a finite 
useful life are reviewed at the end of each reporting period at the least. 
The amortization expense on intangible assets with finite lives is recog-
nized in the consolidated statements of profit or loss in the expense cate-
gory that is consistent with the function of the intangible assets.

A summary of the useful lives applied to the Group’s intangible assets is 
as follows:

Intangible assets

Intellectual property rights

Licenses

Software

Useful life (years)

8-20

3-20

3-8

Intangible assets with indefinite useful lives are tested for impairment 
at least annually, or  when  there is an indication for impairment, either 
individually or at the level of a cash-generating unit (see Note 2.3.10 for  
further details). In the case of intangible assets not yet available for use, 
the point in time from which a capitalized asset can be expected to gen-
erate economic benefit for the Group cannot be determined. Such assets 
are not amortized, and therefore classified as having an indefinite useful 
life. The intangible assets not yet available for use are tested for impair-
ment annually, or when there is an indication for impairment on an indi-
vidual basis. The assessment of indefinite life is reviewed annually to de-
termine whether the indefinite life continues to be supportable. If not, the 
change in useful life from indefinite to finite is made on a prospective basis.

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

We have classified advanced payments on intangible assets as intangible 
assets that are not yet ready for use. Advanced payments on intangible 
assets are tested for impairment on an annual basis.

Depreciation is calculated on a straight-line basis over the estimated use-
ful lives of the assets, as follows:

An intangible asset is derecognized upon disposal (i.e., at the date the 
recipient obtains control) or when no future economic benefits are ex-
pected from its use or disposal. Any gain or loss arising upon derecogni-
tion of the asset (calculated as the difference between the net disposal 
proceeds and the carrying amount of the asset) is included in the consoli-
dated statements of profit or loss.

See Note 2.3.4 for further details in connection with our accounting of 
internally generated intangible assets.

2.3.9 Property, Plant and Equipment

Construction in progress is stated at cost. Property, plant and equipment 
are stated at cost, net of accumulated depreciation and accumulated im-
pairment losses, if any. Such cost includes the cost of replacing part of the 
property, plant and equipment if the recognition criteria are met. All other 
repair and maintenance costs are expensed as incurred.

Property, plant and equipment

Useful life (years)

Buildings

Equipment, tools and installations 

10-33

7-18

Operating and business equipment has a useful life of 1-10 years and is 
reported under equipment, tools and installations due to immateriality. 

An item of property, plant and equipment initially recognized is derecog-
nized upon disposal (i.e., at the date the recipient obtains control) or when 
no future economic benefits are expected from its use or disposal. Any 
gain or loss arising on derecognition of the asset (calculated as the differ-
ence between the net disposal proceeds and the carrying amount of the 
asset) is included in the consolidated statements of profit or loss when the 
asset is derecognized.

The residual values, useful lives and methods of depreciation of property, 
plant and equipment are reviewed at each financial year-end and adjusted 
prospectively, if appropriate.

2.3.10 Impairment of Non-Financial Assets

At each reporting date, we assess whether there is an indication that a 
non-financial asset may be impaired. Goodwill is tested for impairment 
at least annually. Impairment is determined for goodwill by assessing the 
recoverable amount of each cash-generating unit (or group of CGUs) to 
which the goodwill relates. If any indication exists, or when annual impair-
ment testing is performed, we estimate the asset’s or CGU’s recoverable 
amount. The recoverable amount is the higher of an asset’s or CGU’s fair 
value less costs of disposal and its value in use. The recoverable amount 

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

is determined for an individual asset, unless the asset does not generate 
cash inflows that are largely independent of those from other assets or 
groups of assets. If the asset does not generate independent cash in-
flows, the impairment test is performed for the smallest group of assets 
that generate largely independent cash inflows from other assets (CGU). 
When the carrying amount of an asset or cash-generating unit exceeds its 
recoverable amount, the asset or the non-current assets of the CGU are 
considered impaired and written down to their recoverable amount.

Impairment losses are recognized in the consolidated statements of profit 
or loss in expense categories consistent with the function of the impaired 
asset.

Intangible assets with an indefinite useful life are tested for impairment an-
nually at the CGU level, as appropriate, and when circumstances indicate 
that the carrying value may be impaired. 

Intangible assets not yet available for use are not amortized, but rather 
tested for impairment when a triggering event arises or at least once a 
year. The identification of triggering events takes place on a quarterly or 
on an ad hoc basis with the involvement of the responsible departments, 
taking internal and external information sources into consideration. The 
impairment test is performed annually or if there are indications of impair-
ment by determining the asset’s value in use. In assessing value in use, the 
estimated discounted future cash flows are based on long-term forecast 
calculations reflecting the asset’s estimated product life cycles. The as-
sumptions are based on internal estimates along with external market 
studies. The result of the valuation depends to a large extent on the esti-
mates by the management of the future cash flows of the assets and the 
discount rate applied, and is therefore subject to uncertainty.

2.3.11 Financial Instruments

A financial instrument is any contract that gives rise to a financial asset 
of one entity and a financial liability or equity instrument of another entity.

i) Financial Assets
Initial Recognition and Measurement
Financial assets mainly include money market funds, bank deposits and 
reverse repos, security investments, trade receivables, cash at banks as 
well as equity investments. Financial assets are initially measured at fair 
value as of the trade date and – depending on their classification – subse-
quently measured at amortized cost, fair value through other comprehen-
sive income (OCI) or fair value through profit or loss. 

Subsequent Measurement
The measurement of financial assets depends on their classification, as 
described below.

Financial Assets Measured at Amortized Cost
Financial assets measured at amortized cost include trade receivables 
and other financial assets are generally measured using the effective in-
terest rate (EIR) method. With respect to trade receivables, we applied the 
practical expedient, which means that they are measured at the transac-
tion price determined in accordance with IFRS 15. Refer to the accounting 
policies in Note 2.3.3. Other financial assets measured at amortized cost 
are held to collect contractual cash flows, which are solely payments of 
principal and interest. Gains and losses are recognized in our consolidat-
ed statements of profit or loss when the financial asset is derecognized, 
modified or impaired. 

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  REPORT

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Financial Assets Designated at Fair Value through OCI (Equity Instruments)
Upon initial recognition, we can irrevocably elect to classify equity invest-
ments as equity instruments designated at fair value through OCI if they 
meet the definition of equity under IAS 32 and are not held for trading. The 
classification is determined on an instrument-by-instrument basis. Gains 
and losses on these financial assets are never recycled to profit or loss. 
Dividends are recognized as other income in the consolidated statements 
of profit or loss when the right of payment has been established. Equity 
instruments designated at fair value through OCI are not subject to impair-
ment assessment. We elected to irrevocably classify our non-listed and 
listed equity investments under this category. They are recognized using 
trade date accounting.

Financial Assets at Fair Value through Profit or Loss
Derivatives not designated as hedging instruments are measured at fair 
value through profit or loss. A financial asset exists if the derivative has a 
positive fair value.

Derecognition
A financial asset (or, where applicable, a part of a financial asset or part of 
a group of similar financial assets) is primarily derecognized (i.e., removed 
from the consolidated statements of financial position) when the rights to 
receive cash flows from the asset have expired or have been transferred 
in terms of fulfilling the derecognition criteria. 

Impairment of Financial Assets
An  allowance  for  expected  credit  losses  (ECLs)  is  considered  for  all 
non-derivative financial debt investments, including cash, time deposits 
and debt securities of the Group. ECLs are based on the difference be-
tween the contractual cash flows due in accordance with the contract 
and all of the cash flows that the Group expects to receive, discounted at 
an approximation of the original effective interest rate. The expected cash 
flows will include cash flows from the sale of collateral held or other credit 
enhancements that are integral to the contractual terms.

Since our financial debt investments are considered to be investments 
with low risk, the expected credit loss in the upcoming twelve months 
is used to determine the impairment loss. Wherever a considerable in-
crease in the default risk is assumed, the lifetime expected credit loss of 
the financial asset is considered.

For trade receivables and contract assets, the Group applies a simplified 
approach in calculating ECLs. This means that the Group does not track 
changes in credit risk, but instead recognizes a loss allowance based on 
lifetime ECLs at each reporting date. We have established an ECL model 
that is based on the probability of default (PD), considers the respective 
country default probabilities and takes the maturities into account. In or-
der to determine the PD of companies, we use the maturities of the trade 
receivables and the score of the companies. 

If there is objective evidence that certain trade receivables or contract 
assets are fully or partially impaired, additional loss allowances are recog-
nized to account for expected credit losses. A debtor’s creditworthiness 
is assumed to be impaired if there are objective indications that the debtor 
is in financial difficulties, such as the disappearance of an active market for 
its products or impending insolvency. 

ii) Financial Liabilities
Financial liabilities are generally measured at amortized cost using the 
effective interest rate (EIR) method. Derivatives with negative fair values 
not designated as hedging instruments and liabilities for contingent con-
sideration in business combinations are measured at fair value.

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

All financial liabilities are recognized initially at fair value and, in the case 
of loans and borrowings and payables, net of directly attributable trans-
action costs.

Financial liabilities measured at amortized cost include loans and borrow-
ings, trade payables and other financial liabilities. They are measured at 
amortized cost using the EIR method. Gains and losses are recognized 
in the consolidated statements of profit or loss when the liabilities are 
derecognized as well as through the EIR amortization process.

Amortized cost is calculated by taking into account any discount or pre-
mium on acquisition and fees or costs that are an integral part of the EIR. 
The EIR amortization is included as finance costs in the consolidated 
statements of profit or loss.

Derecognition
A financial liability is derecognized when the obligation under the liability 
is discharged or cancelled or expires. When an existing financial liability 
is replaced by another from the same lender on substantially different 
terms, or the terms of an existing liability are substantially modified, such 
an exchange or modification is treated as the derecognition of the original 
liability and the recognition of a new liability. The difference in the respec-
tive carrying amounts is recognized in the consolidated statements of 
profit or loss.

iii) Expenses and Income from Exchange Forward Contracts
Effects from foreign exchange forward contracts, which are measured 
at fair value through profit or loss, are shown as either other operating in-
come or other operating expenses on a cumulative basis and might switch 
between those two items during the year-to-date reporting periods.

2.3.12 Fair Value Measurement

Fair value is a market-based measurement. For some assets and liabilities, 
observable market transactions or market information is available. For 
other assets and liabilities, observable market transactions or market 
information might not be available. When a price for an identical asset or 
liability is not observable, another valuation technique is used. To increase 
consistency and comparability in fair value measurements, there are three 
levels of the fair value hierarchy:

  Level 1 contains the use of quoted prices in active markets for identi-
cal assets or liabilities.

  Level 2 inputs are inputs other than quoted prices included within 
Level 1 that are observable for the asset or liability either directly or 
indirectly. 

  Level 3 inputs are unobservable. 

Within this hierarchy, estimated values are made by management based 
on reasonable assumptions, including other fair value methods.

For assets and liabilities that are recognized in the financial statements  
at fair value on a recurring basis, we determine whether transfers have  
occurred  between  levels  in  the  fair  value  hierarchy  by  re-assessing  
categorization (based on the lowest level input that is significant to the fair 
value measurement as a whole) at the end of each reporting period.

For the purpose of fair value disclosures, classes of assets and liabilities 
have been determined on the basis of the nature, characteristics and risks 
of the asset or liability and the level of the fair value hierarchy, as explained 
above.

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

2.3.13 Inventories

2.3.14 Cash and Cash Equivalents

Inventories are valued at the lower of cost and net realizable value.

Costs incurred in bringing each product to its present location and condi-
tion are accounted for as follows:

  raw materials and supplies: purchase cost on a first-in/first-out ba-
sis; or

  unfinished goods and finished goods: cost of direct materials and 
labor, including both internal manufacturing and third-party contract 
manufacturing organizations, or CMOs, and a proportion of manufac-
turing overheads based on the normal operating capacity, but exclud-
ing borrowing costs.

Net realizable value is the estimated selling price in the ordinary course 
of business less estimated costs of completion and the estimated costs 
necessary to make the sale. Write-offs are recorded if inventories are ex-
pected to be unsaleable, do not fulfill the specification defined by our qual-
ity standards or if their shelf-life has expired. For our inventories subject to 
the collaboration partners’ gross profit share mechanism, we consider the 
contractual compensation payments in the estimate of the net realizable 
value.

Beginning with the second quarter of 2023, pre-launch products from the 
Comirnaty product family with their potential for economic benefit fulfill 
the recognition criteria for an asset under the IFRS Conceptual Frame-
work. At each reporting date, the respective inventory is measured at the 
lower of cost and net realizable value. However, because is not probable 
until regulatory approval is obtained, we consider the net realizable value 
to be zero, as this is the probable amount expected to be realized from its 
sale until approval is obtained (see also Note 2.3.4 for further information 
on our assessment regarding the potential of our pre-launch products to 
produce economic benefits). 

Cash  and  cash  equivalents  comprise  cash  at  banks  and  on  hand  and 
short-term investments that we consider to be highly liquid (including de-
posits, money market funds and reverse repos) with an original maturity 
of three months or less that are readily convertible to a known amount of 
cash and subject to an insignificant risk of changes in value. Deposits with 
an original maturity of more than three months are recognized as other 
financial assets. 

2.3.15 Treasury Shares

We  apply  the  par  value  method  to  our  repurchases  of  outstanding  
American Depositary Shares, or ADSs. Accordingly, the nominal value of 
acquired treasury shares is deducted from equity and shown in the sep-
arate item “Treasury shares”. Any premium paid in excess of the nominal 
value of a repurchased ADS is deducted from the capital reserve. On the 
trade date, we recognize a liability, and on the settlement date, we settle 
in cash. We recognize the foreign exchange differences that may occur 
between the trade and settlement date as profit or loss.

2.3.16 Leases

At the inception of a contract, we assess whether the contract is, or con-
tains, a lease. A contract is, or contains, a lease if the contract conveys 
the right to control the use of an identified asset for a period of time in ex-
change for consideration. To assess whether a contract conveys the right 
to control the use of an identified asset, we assess whether: 

  the contract involves the use of an identified asset – this may be 
specified explicitly or implicitly and should be physically distinct or 
represent substantially all of the capacity of a physically distinct asset. 
If the supplier has a substantive substitution right, then the asset is not 
identified; 

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

  we have the right to obtain substantially all of the economic benefits 
from the use of the asset throughout the period of use; and

  we have the right to direct the use of the asset. We possess this 
right when we hold the decision-making rights that are most relevant 
to changing how and for what purpose the asset is used. In rare cases 
where the decision about how and for what purpose the asset is used 
is predetermined, the Group has the right to direct the use of the asset 
if either:

–  we have the right to operate the asset; or

–   we designed the asset in a way that predetermines how and for 

what purpose it will be used. 

At inception or on reassessment of a contract that contains a lease com-
ponent, the consideration in the contract is allocated to each lease com-
ponent on the basis of their relative standalone prices. However, for leas-
es of land and buildings in which we are a lessee, we have elected not to 
separate non-lease components, and instead account for the lease and 
non-lease components as a single lease component.

The right-of-use asset is subsequently depreciated using the straight-
line method from the commencement date to the earlier of the end of the  
useful life of the right-of-use asset and the end of the lease term. The 
estimated useful lives of right-of-use assets are determined on the same  
basis as those of property, plant and equipment. In addition, the right-of-
use asset is periodically reduced by impairment losses, if any, and adjust-
ed for certain remeasurements of the lease liability.

The lease liability is initially measured at the present value of the lease 
payments that are not paid at the commencement date, discounted using 
the incremental borrowing interest rate implicit in the lease or, if that rate 
cannot be readily determined, the Group’s incremental borrowing rate. 
Generally, the incremental borrowing rate is used as the discount rate.

Lease payments included in the measurement of the lease liability com-
prise the following: 

  fixed payments, including in-substance fixed payments;

  variable lease payments that depend on an index or a rate, initially 
measured using the index or rate as of the commencement date; 

We recognize a right-of-use asset and a lease liability at the lease com-
mencement date. 

  amounts expected to be payable under a residual value guarantee; 
and

The right-of-use asset is initially measured at cost, which comprises the 
initial amount of the lease liability adjusted for any lease payments made 
at or before the commencement date, plus any initial direct costs incurred 
and an estimate of the costs to dismantle and remove the underlying as-
set or to restore the underlying asset or the site on which it is located, less 
any lease incentives received by the Group.

  the exercise price under a purchase option that is reasonably certain 
to be exercised, lease payments in an optional renewal period if it is 
reasonably certain that the extension option is exercised, and penal-
ties for early termination of a lease unless it is reasonably certain that 
the contract will not be terminated early.

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1  MAGAZINE 

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The lease liability is subsequently measured at amortized cost using the 
EIR method. It is remeasured when there is a change in future lease pay-
ments arising from a change in an index or rate, if there is a change in the 
estimate of the amount expected to be payable under a residual value 
guarantee, or if we change our assessment of whether we will exercise 
a purchase, extension or termination option. When the lease liability is 
remeasured, a corresponding adjustment is made to the carrying amount 
of the right-of-use asset or is recorded in the consolidated statements 
of profit or loss if the carrying amount of the right-of-use asset has been 
reduced to zero.

Right-of-use  assets  are  presented  separately  and  lease  liabilities  are 
presented under “Financial liabilities” in the consolidated statements of 
financial position.

Depreciation is calculated on a straight-line basis over the estimated use-
ful lives of the assets or shorter lease term, as follows:

2.3.17 Provisions

Provisions are recognized when there is a present obligation (legal or 
constructive) as a result of a past event, it is probable that an outflow of 
resources embodying economic benefits will be required to settle the 
obligation and a reliable estimate can be made of the amount of the ob-
ligation. When we expect some or all of a provision to be reimbursed, for 
example, under an insurance contract, the reimbursement is recognized 
as a separate asset, but only when the reimbursement is virtually certain. 

A provision is also recognized for certain contracts with suppliers for 
which the unavoidable costs of meeting the obligations exceed the eco-
nomic benefits expected to be received. The economic benefits con-
sidered in the assessment comprise the future benefits we are directly 
entitled to under the contract as well as the anticipated future benefits 
that are the economic consequence of the contract if these benefits can 
be reliably determined.

Right-of-use assets

Buildings

Equipment, tools and installations 

Production facilities 

Automobiles

Useful life or shorter 
lease term (years)

The expense relating to a provision is presented in the consolidated state-
ments of profit or loss net of any reimbursement. 

2-25

2.3.18 Share-Based Payments

2-5

2-3

3-4

Employees (and others providing similar services) receive remuneration 
in the form of share-based payments, which are settled in equity instru-
ments (equity-settled transactions) or in cash (cash-settled transactions). 

Short-Term Leases and Leases of Low-Value Assets
We have elected not to recognize right-of-use assets and lease liabilities 
for short-term leases of machinery that have a lease term of 12 months or 
less or leases of low-value assets. We recognize the lease payments as-
sociated with these leases as an expense in the consolidated statements 
of profit or loss on a straight-line basis over the lease term.

In accordance with IFRS 2, share-based payments are generally divided 
into cash-settled and equity-settled. Both types of payment transactions 
are measured initially at their fair value as of the grant date. The fair value is 
determined using an appropriate valuation model, further details of which 
are given in Note 16. Rights granted under cash-settled transactions are 
remeasured at fair value at the end of each reporting period until the set-
tlement date. The cost of share-based payment awards is recognized 
over the relevant service period, applying either the straight-line method 
or the graded vesting method, where applicable. 

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2.4 Standards Applied for the First Time

In 2023, the following potentially relevant new and amended standards 
and interpretations became effective, but did not have a material impact 
on our consolidated financial statements:

Standards/Interpretations

IFRS 17 Insurance Contracts

Amendments to IFRS 17 Insurance contracts:  
Initial Application of IFRS 17 and IFRS 9 –  
Comparative Information

Amendments to IAS 1 and IFRS Practice Statement 2:  
Disclosure of Accounting Policies

Amendments to IAS 8 Accounting policies,  
Changes in Accounting Estimates and Errors:  
Definition of Accounting Estimates

Amendments to IAS 12 Income Taxes:  
Deferred Tax related to Assets and Liabilities arising  
from a Single Transaction

Amendments to IAS 12 Income taxes:  
International Tax Reform – Pillar Two Model Rules

Date of application

January 1, 2023

January 1, 2023

January 1, 2023

January 1, 2023

January 1, 2023

January 1, 2023

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

These costs are recognized in cost of sales, research and development 
expenses, sales and marketing expenses or general and administrative 
expenses, together with a corresponding increase in equity (other re-
serves) or other liabilities, over the period in which the service is provided 
(the vesting period). The cumulative expense recognized for cash- and 
equity-settled transactions at each reporting date until the vesting date 
reflects the extent to which the vesting period has expired, and also re-
flects the best estimate of the number of equity instruments expected to 
ultimately vest. 

Service and non-market performance conditions are not taken into ac-
count when determining the grant date fair value of awards, but the likeli-
hood of the conditions being met is assessed as part of our best estimate 
of the number of equity instruments that will ultimately vest. Market per-
formance conditions are reflected within the grant date fair value. Any 
other conditions attached to an award, but without an associated service 
requirement, are considered to be non-vesting conditions. Non-vesting 
conditions are reflected in the fair value of an award and lead to an imme-
diate expensing of an award unless there are also service and/or perfor-
mance conditions.

If we have a choice of settling either in cash or by providing equity instru-
ments, the rights granted are accounted for as an equity-settled transac-
tion, unless there is a present obligation to settle in cash. 

If, due to local tax regulations, an amount is withheld for the employee’s 
tax obligations and paid directly to the tax authorities in cash on the em-
ployee’s  behalf,  the  entire  share-based  payment  program  remains  an 
equity-settled plan based on the IFRS 2 classification. Accordingly, the 
amount withheld for the employee’s tax obligations expected to be paid 
directly to the tax authorities is reclassified from “Other reserves” to “Oth-
er non-financial liabilities”.

2.3.19 Cash Dividend

We recognize a liability to pay a dividend when the distribution is autho-
rized. As per the corporate laws of Germany, a distribution is authorized 
when it is approved by the general shareholder meeting. A corresponding 
amount is recognized directly in equity.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

2.5 Standards Issued but Not Yet Effective

The  new  and  amended  standards  and  interpretations  that  are  issued 
but not yet effective by the date of issuance of the financial statements 
and that might have an impact on our financial statements are disclosed  
below.  We  have  not  adopted  any  standards  early  and  intend  to  adopt 
these  new  and  amended  standards  and  interpretations,  if  applicable, 
when they become effective. 

Standards/Interpretations

Amendments to IFRS 16 Leases:  
Lease Liability in a Sale and Leaseback

Amendments to IAS 7 Statement of Cash Flows and  
IFRS 7 Financial Instruments: Disclosures:  
Supplier Finance Arrangements

Amendments to IAS 1 Presentation of Financial Statements:  
Classification of Liabilities as Current or Non-Current

Amendments to IAS 1 Presentation of Financial Statements:  
Non-current Liabilities with Covenants

Amendments to IAS 21 The Effects of Changes in Foreign 
Exchange Rates: Lack of Exchangeability

(1)

Date of application

January 1, 2024

(1)

January 1, 2024

January 1, 2024

January 1, 2024

January 1, 2025

(1)  Standards had not yet been endorsed in the European Union at the time of publication. 

We do not expect a significant impact from the application of any of these 
standards and amendments. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

3  SIGNIFICANT ACCOUNTING 
JUDGEMENTS, ESTIMATES  
AND ASSUMPTIONS

The  preparation  of  the  consolidated  financial  statements  requires  
management to make judgments, estimates and assumptions that affect 
the reported amounts of revenues, expenses, assets and liabilities, the 
accompanying disclosures and the disclosure of contingent liabilities. 
Uncertainty about these assumptions and estimates could result in out-
comes that require a material adjustment to the carrying amount of assets 
or liabilities affected in future periods. 

Significant accounting judgments, as well as key assumptions concerning 
the future and other key sources of estimation uncertainty at the reporting 
date that have a significant risk of causing a material adjustment to the 
carrying amounts of assets and liabilities within the next financial year, are 
described below. We based our assumptions and estimates on parame-
ters available when the consolidated financial statements were prepared. 
Existing circumstances and assumptions about future developments, 
however, may change due to market changes or circumstances arising 
that are beyond the control of the Group. Such changes are reflected in 
the assumptions when they occur.

Revenues from Contracts with Customers

We applied the following judgments, estimates and assumptions that sig-
nificantly affect the determination of the amount and timing of revenues 
from contracts with customers:

Identification and Determination of Performance Obligations

We generate revenues from collaboration and license agreements, which 
contain multiple elements, including licenses to use, research, develop, 
manufacture and commercialize candidates and products, research and 
development services as well as obligations to develop and manufacture 
preclinical and clinical material and products. We determined that those 
collaboration and license agreements qualify as contracts with custom-
ers. A contract is an agreement between two or more parties that estab-
lishes enforceable rights and obligations. At inception of each agreement, 
we apply judgment when determining which promises represent distinct 
performance obligations. If promises are not distinct, they are combined 
until the bundle of promised goods and services is distinct. For some 
agreements, this results in accounting for goods and services promised in 
a collaboration and license agreement as a single performance obligation 
with a single measure of progress. For these combined performance ob-
ligations, we assess which of these promises is the predominant promise 
to determine the nature of the performance obligation. When licenses are 
granted, we determined that the grant of the license is the predominant 
promise within the combined performance obligations. In our view, we 
grant our customers a right to access or a right to use our intellectual 
property due to the collaboration and license agreements. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Measurement of the Transaction Price

Our collaboration and license agreements often include variable con-
sideration, which is contingent on the occurrence or non-occurrence 
of a future event (i.e., reaching a certain milestone). When determining 
deferred revenues from a collaboration and license agreement, we need 
to estimate the amount of consideration to which we will be entitled in ex-
change for transferring the promised goods or services to our customers. 

As there are usually only two possible outcomes (i.e., milestone is reached 
or not), we have assessed that the method of the most likely amount is 
the best method to predict the amount of consideration to which we will 
be entitled. At contract inception, the most likely amount for milestone 
payments is estimated to be zero. We have assessed that the likelihood 
of achieving the respective milestone decreases depending on how far 
the expected date of achieving the milestone lies in the future. At each 
reporting date, we use judgment to determine when to include variable 
consideration in the transaction price in such a way that it is highly proba-
ble that a significant revenue reversal in the amount of cumulative revenue 
recognized will not occur when the associated uncertainty with respect to 
the variable consideration is subsequently resolved. We have concluded 
that future milestone payments are fully constrained at the end of the 
current financial year.

Future milestone payments would become unconstrained upon the satis-
faction of the milestone event, specifically a development event, regulato-
ry approval or achievement of a sales milestone.

Allocation of the Transaction Price to Performance Obligations and 
Revenue Recognition as Performance Obligations are Satisfied

We allocate the transaction price to performance obligations based on 
their relative standalone selling prices, which are generally based on our 
best estimates and interpretations of facts and circumstances of each 
contractual agreement and may require significant judgment to determine 
appropriate allocation.

Upfront payments and reimbursement for expenses are initially deferred 
on our consolidated statements of financial position. We assessed that 
no significant financing component exists within our collaboration agree-
ments since the overall business purpose of advanced payments is to 
support the payment structure rather than to provide a significant benefit 
of financing. For performance obligations in which the costs vary based 
on progress, an input-based measure that takes into account cost in-
curred is the most reliable indicator of the progress of the related re-
search activities. In other cases, revenue recognition on a straight-line 
basis may be the most reliable indicator of our performance toward com-
plete satisfaction. If the contractual activities progress, the achievement 
of development milestones will be used to measure the progress toward 
complete satisfaction. We evaluate the measure of progress in each re-
porting period and, if necessary, adjust the measure of performance and 
related revenue recognition. Any such adjustments are recorded on a 
cumulative catch-up basis, which would affect revenues and net profit or 
loss in the period of adjustment.

Upon successfully commercializing a pharmaceutical product, the collab-
oration and license agreements also provide for additional profit-sharing 
or tiered royalties earned when customers recognize net sales of licensed 
products as well as sales milestone payments. Revenue is recognized 
based on the sales-based or usage-based royalty exemption; i.e., when, or 
as, the underlying sales occur, which is when the performance obligation 
has been satisfied. 

Principal-Agent Considerations

Collaboration agreements that involve two or more partners who con-
tribute to the provision of a specific good or service to a customer are 
assessed in terms of principal-agent considerations. Under our current 
collaboration agreements, the allocation of marketing and distribution 
rights defines territories in which the collaboration partner acts as a prin-
cipal in each case. We recognize revenue net based on the collaboration 
partners’ gross profit in territories where the partner is responsible for 
supply, and on a gross basis when directly supplying our customers in 
our territories when control has been transferred. Amounts paid to col-
laboration partners for their share of our profits earned where we are the 
principal in the transaction are recorded as cost of sales. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Pfizer Agreement Characteristics

With  respect  to  our  collaboration  with  Pfizer,  commercial  revenues 
are recognized based on our collaboration partner’s gross profit from 
COVID-19 vaccine sales, which is shared under the respective collabo-
ration agreement. In determining commercial revenues pursuant to this 
collaboration agreement, we are reliant on our collaboration partner for 
details regarding its gross profit for the period at hand. Some of the infor-
mation which our collaboration partner provides us with to identify the 
gross profit is, by necessity, preliminary and subject to change. 

Pfizer’s gross profit share is calculated based on sales and takes into 
account transfer prices. The latter include manufacturing and shipping 
costs, which represent standard prices and include mark-ups on manu-
facturing costs as specified by the terms of the agreement. Manufactur-
ing and shipping cost variances were considered as far as those have 
been identified. Nevertheless, those input parameters may be adjusted 
once actual costs are determined. The sales as reported by Pfizer have 
been used to estimate license obligations in terms of royalties and sales 
milestones. Sales milestones and royalties are recognized as they are 
earned by the partners. Sales milestones are shared equally, while royalty 
payments are borne by the partners on the basis of revenues in the terri-
tories for which the partners are responsible and subsequently deducted 
as cost under the gross profit shared. The estimated royalty fees applied 
to net sales reflect the license obligations to the extent currently identified 
from third-party contractual arrangements. Changes in estimates are ac-
counted for prospectively, when determined. 

Manufacturing cost variances include expenses from unused contract 
manufacturing capacities and overstock inventories finally scrapped. As 
only materialized costs – which means manufacturing capacities finally 
lapsed or inventories finally scrapped – are shared with the partner in a 
cash-effective manner, the gross profit share impact is anticipated once 
assessed as being highly probable to occur. Therefore, information on 
Pfizer’s write-downs of inventories is considered. Any changes to this 
assessment will be recognized prospectively.

Pfizer’s determination of manufacturing and shipping costs also affects 
the transfer prices that have been charged to COVID-19 vaccine supplies 
that it manufactures and supplies to us and may be subject to adjustment 
whenever manufacturing and shipping cost variances are identified. Like-
wise, our own cost of sales and the respective gross profit share owed 
to our partner may be adjusted prospectively, when changes are deter-
mined. 

For contract balances related to the Pfizer agreement, see Note 6. Judg-
ment is required in determining whether a right to consideration is uncon-
ditional and thus qualifies as a receivable. 

Provisions and Contingencies

We are currently confronted with a number of claims and legal proceed-
ings. They include claims from third parties demanding indemnification 
for alleged infringement of a third-party patent or other intellectual propri-
etary rights, as well as product liability claims. In respect of these matters, 
we assess whether provisions must be recorded and whether contingen-
cies must be reported. 

Due to uncertainties relating to these matters, provisions and contingen-
cies are based on the best information available.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Significant judgment is required in the determination of whether and when 
a provision is to be recorded and what the appropriate amount for such 
provision should be. Notably, judgment is required in the following areas:

For further disclosures and carrying amounts relating to provisions as well 
as contingencies, see Note 17 and Note 18.

  Determining whether an obligation exists

Research and Development Expenses

  Determining the probability of an outflow of economic benefits

  Determining whether the amount of an obligation is reliably estimable

  Estimating  the  amount  of  the  expenditure  required  to  settle  the  
present obligation

At the end of each reporting period, we reassess the potential obligations 
related to our pending claims and litigation and adjust our respective pro-
visions and contingencies to reflect the current best estimate. In addition, 
we monitor and evaluate new information that we receive after the end 
of the respective reporting period, but before the consolidated financial 
statements are authorized for issue, in order to determine whether this 
provides additional information regarding conditions that existed at the 
end of the reporting period. Changes to estimates, assumptions and out-
comes compared to previous estimates and assumptions could require 
material adjustments to the carrying amounts of the respective provisions 
recorded and additional provisions.

The expected timing or amounts of any outflows of economic benefits 
resulting from these lawsuits and claims are uncertain and difficult to 
estimate or even not estimable, as they generally depend on the duration 
of the legal proceedings and settlement negotiations required to resolve 
the litigation and claims and the unpredictability of the outcomes of legal 
disputes in several jurisdictions.

Disclosures in respect of third-party claims and litigation for which no 
provisions have been recognized are made in the form of contingent liabil-
ities, unless a potential outflow of resources is considered remote. It is not 
practicable to estimate the financial impact of contingent liabilities due to 
the uncertainties around lawsuits and claims as outlined above. 

The nature of our business and primary focus of our activities, including 
development of our platforms and manufacturing technologies, generate 
a significant amount of research and development expenses. Research 
costs are expensed as incurred. Development expenditures on an indi-
vidual project are recognized as an intangible asset if, and only if, the cap-
italization criteria are met. Based on our assessment, we have concluded 
that, due to the inherent risk of failure in pharmaceutical development 
and the uncertainty of approval, these criteria are usually not met before 
regulatory approval is achieved. The related expenditure is reflected in 
the consolidated statements of profit or loss in the period in which the ex-
penditure is incurred. We have entered into agreements under which third 
parties grant licenses to us, which are known as in-license agreements. If 
in-licensing results in consideration for the acquisition of intellectual prop-
erty that meets the definition of an identifiable asset, this is capitalized as 
an intangible asset. If the transaction also includes research and develop-
ment services to be provided by the licensor, the share of consideration 
attributable to these services is recognized in research and development 
expenses in line with the performance of the services. The allocation of 
consideration attributable to the acquisition of intellectual property and 
consideration  attributable  to  the  research  and  development  services 
provided by the licensor requires management to make judgements and 
assumptions. These judgments and assumptions can materially affect our 
research and development expenses.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Business Combinations

In our accounting for business combinations, judgment is required in de-
termining whether an intangible asset is identifiable and whether it should 
be recorded separately from goodwill. Additionally, estimating the acqui-
sition-date fair values in conjunction with purchase price allocation in-
volves estimation uncertainty and discretionary decisions. The necessary 
measurements are based on information available on the acquisition date 
and on expectations and assumptions that have been deemed reason-
able by management. These judgments, estimates and assumptions can 
materially affect our financial position and profit. 

Intangible Assets 

Significant assumptions and estimates are required to determine the ap-
propriate amount of amortization of intangible assets. They relate in par-
ticular to the determination of the underlying useful life. The useful life of an 
intangible asset is based on our estimates regarding the period over which 
the intangible asset is expected to generate economic benefits for us. 

Significant assumptions and estimates are also required for the identifica-
tion of a potential need to recognize an impairment loss. These estimates 
include management’s assumptions regarding future cash flow projec-
tions and economic risks that require significant judgment and assump-
tions about future developments. They can be affected by a variety of 
factors, including, but not limited to, changes in business strategy, internal 
forecasts and the estimation of weighted average cost of capital. 

Changes to the assumptions underlying our assessment of the impair-
ment of goodwill and intangible assets could require material adjustments 
to the carrying amount of our recognized goodwill and intangible assets, 
as well as to the amounts of impairment charges recognized in profit or loss.

Share-Based Payments

Determining the fair value of share-based payment transactions requires 
the most appropriate valuation for the specific program, which depends 
on the underlying terms and conditions. We used valuation models such 
as a binomial or Monte Carlo simulation model for the measurement of the 
cash- and equity-settled transactions’ fair value, taking into account cer-
tain assumptions relating to a number of factors, including the volatility of 
the stock price, the determination of an appropriate risk-free interest rate, 
expected dividends and the probability of reaching a minimum hurdle to 
exercise the relevant options. For awards which were granted prior to the 
initial public offering, at a time where no quoted market prices existed, the 
valuation model assumptions included the option’s underlying share price. 
For awards which were granted after the initial public offering, the grant 
date’s share prices on the Nasdaq Global Select Market were included in 
the valuation. 

A fluctuation assumption is applied when estimating the number of equity 
instruments for which service conditions are expected to be satisfied 
and will be revised if material differences arise. Ultimately, a true-up to the 
number satisfied by the settlement date will be recorded. 

For further disclosures relating to share-based payments, see Note 16.

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Our management continued to take the view that deferred tax assets 
on tax losses carried forward that relate to subsidiaries which have a 
loss-making history cannot be recognized. This includes the assessment 
that those subsidiaries have neither any taxable temporary differences 
nor any tax planning opportunities available that could support the recog-
nition of deferred tax assets. 

For further disclosures relating to deferred taxes, see Note 8.

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Income Taxes

We are subject to income taxes in more than one tax jurisdiction. Due to the 
increasing complexity of tax laws and the corresponding uncertainty re-
garding the legal interpretation by the fiscal authorities, tax calculations are 
generally subject to an elevated amount of uncertainty. To the extent neces-
sary, possible tax risks are taken into account in the form of provisions. 

We do not recognize or we would impair deferred tax assets if it is unlike-
ly that a corresponding amount of future taxable profit will be available 
against which the deductible temporary differences, tax loss carry for-
wards and tax credits can be utilized. The assessment whether a deferred 
tax asset can be recognized or is impaired requires significant judgment, 
as we need to estimate future taxable profits to determine whether the 
utilization of the deferred tax asset is probable. In evaluating our ability to 
utilize our deferred tax assets, we consider all available positive and neg-
ative evidence, including the level of historical taxable income and projec-
tions for future taxable income over the periods in which the deferred tax 
assets are recoverable. Based on the requirements in IAS 12, to not place 
reliance on future events that are uncertain as they for example cannot be 
controlled, managements assessment takes particular into account the 
fact that there is an inherent risk of failure in pharmaceutical development 
and an uncertainty of approval which is dependent on external regulatory 
agencies’  opinions.  This  also  includes  management’s  assessment  on 
the character and amounts of taxable future profits, the periods in which 
those profits are expected to occur, and the availability of tax planning 
opportunities. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

4 GROUP INFORMATION

Information about Subsidiaries

The consolidated financial statements include the following subsidiaries:

Name

Country of incorporation

Registered office

December 31, 2023

December 31, 2022

% equity interest

BioNTech BioNTainer Holding GmbH

BioNTech Cell & Gene Therapies GmbH

BioNTech Delivery Technologies GmbH

BioNTech Diagnostics GmbH

BioNTech Europe GmbH

BioNTech Idar-Oberstein Services GmbH

BioNTech Individualized mRNA Manufacturing GmbH

BioNTech Innovation and Services Marburg GmbH

BioNTech Innovation GmbH

BioNTech Innovative Manufacturing Services GmbH

BioNTech Manufacturing GmbH

BioNTech Manufacturing Marburg GmbH

BioNTech Real Estate Holding GmbH

BioNTech Real Estate Verwaltungs GmbH

InstaDeep DE GmbH

JPT Peptide Technologies GmbH

NT Security and Services GmbH

reSano GmbH

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Germany

Mainz(3)

Mainz(3)

Halle(3)

Mainz(3)

Mainz(3)

Idar-Oberstein(3)

Mainz(3)

Marburg(3)

Mainz(3)

Idar-Oberstein(3)

Mainz(3)

Marburg(3)

Holzkirchen(3)

Holzkirchen(3)

Berlin

Berlin(3)

Mainz(3)

Mainz(3)

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

n/a (2)

100%

100%

100%

(1) 

Included during the year ended December 31, 2023.

(2)  Fully acquired during the year ended December 31, 2023.

(3)  Subsidiary makes use of the exemption of Sections 264 para. 3 and 264b HGB for the 2023 financial year.

Continued on next page

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Information about Subsidiaries

Name

BioNTech Australia Pty Ltd.

BioNTech R&D (Austria) GmbH

BioNTech (Shanghai) Pharmaceuticals Co. Ltd.

InstaDeep France SAS

Biopharma BioNTech Israel Ltd.

New Technologies Re

InstaDeep Nigeria Limited

BioNTech Rwanda Ltd.

BioNTech Sénégal Suarl

BioNTech Pharmaceuticals Asia Pacific Pte. Ltd.

BioNTech Pharmaceuticals Spain S.L

BioNTech Switzerland GmbH

BioNTech Taiwan Co. Ltd.

InstaDeep Tunisia SARL

BioNTech Turkey Tıbbi Ürünler Ve Klinik Araştirma Ticaret Anonim Şirketi

BioNTech UK Ltd.

InstaDeep Ltd.

BioNTech Research and Development, Inc.

BioNTech USA Holding, LLC

BioNTech US Inc.

BioNTech Delivery Technologies (US), LLC

InstaDeep LLC

JPT Peptide Technologies Inc.

Country of incorporation

Registered office

December 31, 2023

December 31, 2022

% equity interest

Australia

Austria

China

France

Israel

Melbourne

Vienna

Shanghai

Paris

Tel Aviv

Luxembourg

Luxembourg

Nigeria

Rwanda

Senegal

Singapore

Spain

Switzerland

Taiwan

Tunisia

Türkiye

United Kingdom

United Kingdom

United States 

United States 

United States 

United States 

United States 

United States 

Lagos

Kigali

Dakar

Singapore

Barcelona

Basel

Taipei

Tunis

Istanbul

London

London

Cambridge

Cambridge

Cambridge

Cambridge

Dover

Cambridge

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

100%

n/a(2)

n/a(1)

n/a(1)

n/a(2)

100%

n/a(1)

100%

n/a(1)

n/a(1)

n/a(1)

n/a(2)

100%

100%

5.3%(2)

100%

100%

100%

n/a(2)

n/a(2)

100%

(1) 

Included during the year ended December 31, 2023.

(2)  Fully acquired during the year ended December 31, 2023.

(3)  Subsidiary makes use of the exemption of Sections 264 para. 3 and 264b HGB for the 2023 financial year. 

All entities listed above are included in our consolidated financial statements.

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Parent Company

ATHOS KG, Holzkirchen, Germany, is the sole shareholder of AT Impf 
GmbH, Munich, Germany, and beneficial owner of the following percent-
age of ordinary shares in BioNTech at the dates as indicated. ATHOS KG  
via AT Impf GmbH has de facto control over BioNTech based on its sub-
stantial shareholding, which practically enables it to exercise the majority  
of voting rights to pass resolutions at our Annual General Meeting, or AGM. 

Name

AT Impf GmbH

Country of incorporation

Registered office

December 31, 2023

December 31, 2022

Germany

Munich

43.77%

43.42%

Ownership of ordinary shares in BioNTech (in %)

Entity with Significant Influence over the Group

Medine GmbH, Mainz, Germany, owned the following percentage of ordi-
nary shares in BioNTech at the following dates as indicated: 

Name

Medine GmbH

Country of incorporation

Registered office

December 31, 2023

December 31, 2022

Germany

Mainz

17.01%

17.38%

Ownership of ordinary shares in BioNTech (in %)

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

5 BUSINESS COMBINATIONS

Acquisition of InstaDeep Ltd.

In  July  2023,  we  acquired  InstaDeep  Ltd.,  London,  United  Kingdom  
(InstaDeep), a leading global technology company in the field of artificial 
intelligence (AI) and machine learning, by purchasing 100% of the re-
maining shares in InstaDeep not already owned by us. The acquisition is 
intended to create a fully integrated, enterprise-wide capability that lever-
ages AI and machine learning technologies across our therapeutic plat-
forms and operations. InstaDeep also continues to provide its services to 
clients around the world in diverse industries, including in the technology, 
transport and logistics, and industrial and financial services sectors.

The completion of the acquisition took place in July 2023. We performed 
an allocation of the total consideration and the underlying assets acquired 
(including certain identified intangible assets such as InstaDeep’s Deep-
Chain technology and customer relationships) and liabilities assumed 
based on their fair values using the information available as of the acqui-
sition date. The total consideration and the fair values in accordance with 
IFRS 3 of the identified net assets acquired of InstaDeep as of July 31, 
2023, are as follows:

(in millions €)

Assets 

Intangible assets

Property, plant and equipment 

Right-of-use assets

Trade receivables

Financial assets - current

Cash and cash equivalents

Other assets non-current and current

Total assets

Liabilities

Deferred tax liabilities

Other liabilities long-term and short-term

Total liabilities

Total identifiable net assets at fair value

Goodwill from the acquisition

Total consideration 

Consideration

Cash paid

Cash to be paid in 2024

Designated FX hedge

Shares transferred (approx. 1.1 million shares)

Contingent consideration

Previously held non-listed equity investment (stake of 5.3%)

Total consideration 

Fair value recognized  
on acquisition

InstaDeep Ltd.

187.6

2.1

0.7

2.4

52.5

21.2

8.7

275.0

45.8

18.2

64.0

211.0

306.5

517.5

358.1

4.0

(8.1)

103.7

31.8

27.9

517.5

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The  goodwill  mainly  comprises  the  value  of  expected  synergies  from 
including AI and machine learning technologies across our therapeutic 
platforms and operations and intangible assets that are not recognized 
separately,  such  as  the  acquired  skilled  workforce  and  its  know-how. 
Therefore, the goodwill is allocated almost in full to the CGU immunother-
apies and to a minor extent to a CGU comprising the external InstaDeep 
business. The goodwill is not tax deductible.

Deferred tax liabilities relating to temporary differences of the assets 
acquired in the business combination were recognized in an amount of 
€45.8 million. In line with the deferred tax liabilities assumed, deferred 
tax assets relating to temporary differences and tax loss carry forwards 
which existed as of the acquisition date were recognized. The deferred 
tax assets and liabilities were offset to the extent that the conditions for 
offsetting were fulfilled.

Since the acquisition, InstaDeep’s impact on our revenue and profit for the 
period has been immaterial. Accordingly, hypothetical amounts for our 
revenue and profit for the financial year, which were calculated on the as-
sumption that the acquisition had taken place at the beginning of the year, 
would not materially differ from the actual figures reported. 

The  intangible  assets  acquired  comprise  DeepChain  technology  and 
customer  relationships.  Their  fair  values  were  determined  based  on  
the  multi-period  excess  earnings  method  (MEEM)  and  amount  to 
€176.0 million and €7.8 million respectively.

The fair value of the shares transferred is determined based on the num-
ber of shares transferred and the closing price of the ADSs as of July 31, 
2023.

The acquisition of InstaDeep is a step acquisition in accordance with IFRS 
3.41-3.42A since we already held a 5.3% interest prior to the acquisition. In 
prior reporting periods, we recognized changes in the value of this equity 
interest in other comprehensive income. The amount of the remeasure-
ment to fair value that was recognized in other comprehensive income is 
recognized on the same basis as would be required if we disposed direct-
ly of the previously held equity interest. Based on the total consideration 
for the acquired shares (94.7%), the value of the already held shares is 
€27.9 million, which results in a loss of €2.2 million shown in other compre-
hensive income in the year ended December 31, 2023.

At the acquisition date, the contingent consideration was recognized at 
its fair value of €31.8 million based on cash flow projections in connec-
tion with performance-based future milestone cash payments to eligible 
shareholders after a three-year earn-out period. The lower end of the 
bandwidth of possible outcomes of the contingent consideration is zero; 
the upper limit is €124.6 million. In addition, €12.5 million of potential earn-
out payments are considered remuneration and will be recognized as 
personnel expense over a three-year period in which services are to be 
provided.

Transaction costs of €6.0 million were expensed and are included in gen-
eral and administrative expenses.

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

6  REVENUES FROM CONTRACTS 

WITH CUSTOMERS

6.1 Disaggregated Revenue Information

the  year  ended  December  31,  2021,  revenues  recognized  from  Pfizer 
(€15,500.0 million) and the German Federal Ministry of Health (€1,945.6 
million), accounted for more than 10% of total revenues. During the year 
ended December 31, 2023, based on the geographic region in which our 
customers and collaboration partners are located, we mainly recognized 
revenues in the United States (€3,010.9 million) and Germany (€482.7 mil-
lion). During the year ended December 31, 2022, the main geographic re-
gions were United States (€12,709.7 million) and Germany (€3,031.0 mil-
lion). During the year ended December 31, 2021, the main geographic 
regions were United States (€14,636.5 million), Germany (€2,241.9 million) 
and Belgium (€675.0 million).

Set out below is the disaggregation of the Group’s revenues from con-
tracts with customers:

Commercial Revenues

(in millions €)

Commercial revenues

COVID-19 vaccine revenues

  Sales to collaboration partners

 Direct product sales to  
customers

 Share of collaboration partners’ 
gross profit and sales milestones

Other sales

Research & development  
revenues from collaborations

Years ended December 31,

2023

3,815.5

3,776.2

275.3

2022

17,194.6

17,145.2

1,224.3

2021

18,874.0

18,806.8

970.9

473.6

3,184.7

3,007.2

3,027.3

12,736.2

14,828.7

39.3

3.5

49.4

116.0

67.2

102.7

Total

3,819.0

17,310.6

18,976.7

During the year ended December 31, 2023, commercial revenues were 
recognized from the supply and sales of our COVID-19 vaccine world-
wide. During the year ended December 31, 2023, our commercial reve-
nues decreased in line with a lower COVID-19 vaccine market demand. 
In addition, write-downs by our collaboration partner Pfizer Inc. (Pfizer), 
significantly reduced our gross profit share and hence negatively influ-
enced our revenues for the year ended December 31, 2023. We are the 
marketing authorization holder in the United States, the European Union, 
the United Kingdom, Canada and other countries, and holder of emer-
gency use authorizations or equivalents in the United States (jointly with 
Pfizer) and other countries. Pfizer has marketing and distribution rights 
worldwide with the exception of China, Germany and Türkiye. Shanghai 
Fosun Pharmaceutical (Group) Co., Ltd, or Fosun Pharma, has marketing 
and distribution rights in China, Hong Kong special administrative region, 
or SAR, Macau SAR and the region of Taiwan. The allocation of marketing 
and distribution rights defines territories in which the collaboration part-
ners act as a principal.

During the year ended December 31, 2023, revenues recognized from 
Pfizer Inc., or Pfizer (€3,293.0 million) and the German Federal Ministry 
of Health (€473.6 million), each account for more than 10% of total reve-
nues. During the year ended December 31, 2022, revenues recognized 
from Pfizer (€13,795.8 million) and the German Federal Ministry of Health 
(€3,020.5 million) represented more than 10% of total revenues. During 

Sales to Collaboration Partners
Sales to collaboration partners represent sales of products manufac-
tured by us to collaboration partners. Whenever responsibilities in the 
manufacturing and supply process of the COVID-19 vaccine shift and 
the COVID-19 vaccine is transferred, the vaccine is sold from one part-
ner to the other. Under the collaboration with Pfizer, from time to time, 

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

those sales are significantly influenced by amounts due to write-downs of  
inventories as well as costs related to production capacities derived from 
contracts with CMOs that became redundant. Those costs represent 
accrued manufacturing variances and are charged to our partner once fi-
nally materialized. These manufacturing variances are reflected as trans-
fer price adjustments once identified. The regular reassessment of these 
manufacturing  variances  may  result  in  adjustments  to  the  respective 
prior-period revenues. Sales to collaboration partners during the years 
ended December 31, 2023, 2022 and 2021 of €74.5 million, €850.0 million 
and €31.0 million, respectively, related to the aforementioned manufactur-
ing variances.

Direct Product Sales to Customers
Direct product sales are recognized from supplying COVID-19 vaccine in 
our territories Germany and Türkiye. During the years ended December  
1, 2023, 2022 and 2021, we recognized €473.6 million, €3,184.7 million  
and €3,007.2 million of revenues, respectively. The share of gross profit 
that we owe our collaboration partner Pfizer based on our sales is recog-
nized as cost of sales. 

Share of Collaboration Partners’ Gross Profit and Sales Milestones
Based on COVID-19 vaccine sales in the collaboration partners’ territories, 
we are eligible to receive a share of their gross profit, which represents a 
seasonally affected net figure and is recognized as collaboration revenue 
during the commercial phase, together with sales milestones. Manufac-
turing cost variances either reflected as transfer price adjustments as 
described above or resulting from costs highly probable to be incurred 
by the partner, were taken into account when determining the gross prof-
it. During the year ended December 31, 2021, those revenues included 
€476.6 million of sales milestones. 

The revenues from contracts with customers disclosed above were rec-
ognized as follows: 

(in millions €)

2023

2022

2021

Years ended December 31,

Timing of revenue recognition

 Goods and services  
transferred at a point in time

 Goods and services  
transferred over time

 Revenue recognition  
applying the sales-based  
or usage-based royalty  
recognition constraint mode l (1)

Total

776.3

4,447.2

4,034.3

15.4

127.2

113.7

3,027.3

3,819.0

12,736.2

17,310.6

14,828.7

18,976.7

(1) 

 Represents sales based on the share of the collaboration partners’ gross profit and sales milestones.

6. 2 Contract Balances

(in millions €)

December 31, 2023

December 31, 2022

Trade and other receivables 

Contract liabilities

Refund liabilities

2,155.7

751.8

—

7,145.6

125.5

24.4

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Trade and other receivables significantly decreased compared to the 
previous year and predominantly comprise trade receivables from our 
COVID-19 collaboration with Pfizer as well as our direct product sales to 
customers in our territory. The contractual settlement of the gross profit 
share has a temporal offset of more than one calendar quarter. As Pfizer’s 
financial quarter for subsidiaries outside the United States differs from 
ours, it creates an additional time lag between the recognition of revenues 
and the payment receipt. Consequently, as of December 31, 2023, our 
trade receivables included, in addition to the profit share for the fourth 
quarter of 2023, trade receivables which related to the gross profit share 
for the third quarter of 2023.

Contract liabilities significantly increased compared to the previous year 
as advance payments in connection with the amendment of the COVID-19 
vaccine  purchase  agreement  with  the  European  Commission,  or  EC, 
were received. As of December 31, 2023, the contract liabilities included 
€386.4  million  of  such  payments  under  our  collaboration  with  Pfizer 
(COVID-19 vaccine), €302.3 million from the German Federal Ministry of 
Health and €62.3 million of remaining upfront fees from our collaboration 
agreement with Pfizer (Zoster) (as of December 31, 2022: €65.7 million of 
remaining upfront fees from collaboration and commercial supply agree-
ments and €56.3 million of advance payments for future COVID-19 vac-
cine sales). 

The refund liabilities recognized as of December 31, 2022, represented 
consideration which was refunded to the collaboration partner during the 
year ended December 31, 2023. 

Set  out  below  is  the  amount  of  revenue  recognized  for  the  periods  
indicated:

(in millions €)

2023

2022

2021

Years ended December 31, 

Amounts included in contract  
liabilities at the beginning  
of the year

3.5

63.1

73.7

6.3 Performance Obligations

The contract liabilities allocated to the remaining performance obligations 
from collaboration or commercial supply agreements (unsatisfied or par-
tially unsatisfied) as of year-end are as follows:  

(in millions €)

Within one year

More than one year

Total

December 31, 2023

December 31, 2022

353.3

398.5

751.8

77.1

48.4

125.5

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

7  INCOME AND  
EXPENSES

7.1 General Expenses

Cost of Sales

From the year ended December 31, 2022 to the year ended December 31, 
2023, cost of sales decreased by €2,395.2 million or 80% from €2,995.0 
million to €599.8 million, mainly due to recognizing lower cost of sales 
from our decreased COVID-19 vaccine sales, which included the share 
of gross profit that we owe our collaboration partner Pfizer based on our 
sales. In addition, cost of sales was impacted by expenses arising from 
inventory write-offs and expenses for production capacities derived from 
contracts with CMOs that became redundant. The effects were driven 
by reducing production capacities as well as further fostering the global 
production network with our collaboration partners during the year end-
ed December 31, 2023. Based on the regulatory approval obtained with 
respect to our Omicron XBB.1.5-adapted monovalent COVID-19 vaccine 
during the third quarter of 2023, we reversed the initial write-down of 
pre-launch inventory recorded in research and development expensed 
to a maximum of the original cost of €46.9 million. Thereof €27.3 million 
resulted in cost of sales during the year ended December 31, 2023 as the 
respective inventory has been either sold or written down. The remain-
der is presented in inventories as of December 31, 2023 and amounted 
to €19.6 million. With respect to the year ended December 31, 2022 the 
amount was nil.

Research and Development Expenses

From the year ended December 31, 2022 to the year ended December 31, 
2023, our research and development expenses increased by €246.1 mil-
lion or 16% from €1,537.0 million to €1,783.1 million, mainly influenced by 
progressing clinical studies for pipeline candidates as well as by our newly 
acquired product candidates and the development of variant adapted 
COVID-19 vaccines. The increase was further driven by an increase in 
wages, benefits and social security expenses resulting from a significant 
increase in headcount.

Sales and Marketing Expenses

From the year ended December 31, 2022 to the year ended December 31, 
2023, our sales and marketing expenses increased by €3.2 million or 5% 
from €59.5 million to €62.7 million, mainly due to increased expenses for 
setup and enhancement of commercial IT platforms and an increase in 
wages, benefits and social security expenses resulting from an increase 
in headcount. 

General and Administrative Expenses

From the year ended December 31, 2022 to the year ended December 31, 
2023, our general and administrative expenses increased by €13.3 mil-
lion or 3% from €481.7 million to €495.0 million, mainly influenced by in-
creased expenses for IT services as well as by wages, benefits and social 
security expenses resulting from an increase in headcount. 

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  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

7.2 Other Operating Expenses

7.3 Other Operating Income

Years ended December 31,

Years ended December 31,

(in millions €)

Foreign exchange differences, net

Loss on derivative instruments at 
fair value through profit or loss

Litigation costs (1)

Other

Total

2023

252.0

—

29.4

11.6

293.0

2022

—

385.5

3.0

21.5

410.0

2021

(in millions €)

2023

2022

2021

—

Gain on derivative instruments at 
fair value through profit or loss

86.3

Government grants

9.0

8.1

Foreign exchange differences, net

Other

103.4

Total

67.6

2.2

—

35.2

105.0

—

1.4

727.4

86.5

815.3

5.7

137.2

446.3

9.2

598.4

(1)  Adjustments to prior-year figures relate to costs for external legal advice in connection with certain legal 

litigations from general and administrative expenses to other operating expense to reflect changes in 

internal reporting also in the external reporting.

During the year ended December 31, 2023, the other expenses increased 
compared to the year ended December 31, 2022, which was mainly de-
rived from recognizing foreign exchange differences arising on operating 
items. The foreign exchange differences included in operating expenses 
primarily arose from valuing our U.S. dollar-denominated trade receiv-
ables which were mainly incurred under our COVID-19 collaboration with 
Pfizer, U.S. dollar-denominated trade payables as well as U.S. dollar-de-
nominated other financial liabilities which mainly relate to obligations in-
curred from our license agreements.

During the year ended December 31, 2022, the other operating expenses 
increased compared to the year ended December 31, 2021, mainly from 
recording the change in fair value of foreign exchange forward contracts 
that were entered into during the year ended December 31, 2022, to man-
age some of our transaction exposures but were not designated as hedg-
ing instruments under IFRS. 

During the year ended December 31, 2023, the other income decreased 
compared to the year ended December 31, 2022, as foreign exchange 
differences arising on operating items changed from a positive effect  
to  a  negative  effect,  which  is  recorded  in  other  operating  expenses  
(see Note 7.2). 

During the year ended December 31, 2022, the other income increased 
compared to the year ended December 31, 2021, which was mainly due 
to recognizing foreign exchange differences arising on operating items. 
The foreign exchange differences included in operating income primarily 
arose from valuing our U.S. dollar-denominated trade receivables which 
were mainly incurred under our COVID-19 collaboration with Pfizer, U.S. 
dollar-denominated trade payables as well as U.S. dollar-denominated 
other financial liabilities which mainly relate to obligations incurred from 
our license agreements.

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

7.4 Finance Income

(in millions €)

Interest income

Fair value adjustments of financial 
instruments measured at fair value

Foreign exchange differences, net

Total

During  the  year  ended  December  31,  2023,  the  finance  expenses  in-
creased compared to the year ended December 31, 2022, mainly due to 
exchange differences derived from our foreign exchange bank deposits 
and cash accounts.

2021

1.5

—

66.2

67.7

During the year ended December 31, 2022, the finance expenses de-
creased compared to the year ended December 31, 2021, mainly due to 
final settlement of the derivative embedded within the convertible note 
which led to financial income whereas during the year ended Decem-
ber 31, 2021, expenses in the amount of €277.8 million were derived from 
the respective fair value measurement adjustment.

Years ended December 31, 

2023

357.6

162.0

—

519.6

2022

48.5

216.8

65.0

330.3

During the year ended December 31, 2023, the finance income increased 
compared to the year ended December 31, 2022, mainly due to interest 
income earned on bank deposits and financial securities as well as fair 
value adjustments in relation to our money market funds.

7.6 Employee Benefits Expense

During the year ended December 31, 2022, the finance income included 
the final fair value measurement adjustments of the derivative embedded 
within the convertible note upon the early redemption of the convert-
ible note as of March 1, 2022, the redemption date, as well as interest in-
come from our bank deposits and increased compared to the year ended  
December 31, 2021.

(in millions €)

Wages and salaries

Social security costs

Pension costs

Total

Years ended December 31, 

2023

617.8

76.7

4.1

698.6

2022

544.8

58.6

2.1

605.5

2021

345.9

31. 7

1.2

378.8

7.5 Finance Expenses

Wages and salaries include, among other things, expenses for share-
based payments.

(in millions €)

Foreign exchange differences, net

Fair value adjustments of financial 
instruments measured at fair value

Other

Total

Years ended December 31, 

2023

16.0

—

7.9

23.9

2022

—

—

18.9

18.9

2021

—

277.8

27.3

305.1

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

8 INCOME TAX

The  following  table  illustrates  the  current  and  deferred  taxes  for  the  
periods indicated: 

Income tax for the years ended December 31, 2023, December 31, 2022, 
and December 31, 2021, comprised current income taxes, other taxes 
and deferred taxes. We are subject to corporate taxes, the solidarity sur-
charge and trade taxes. Our corporate tax rate in the reporting year re-
mained unchanged (15.0%) as did the solidarity surcharge (5.5%) where-
as the average trade tax rate changed resulting in a combined income 
tax rate of 27.1% in the year ended December 31, 2023 (during the years 
ended December 31, 2022 and 2021: 27.2% and 30.7%, respectively). 
Deferred taxes are calculated at a rate of 27.1%. Current taxes for Austria 
are calculated at a corporate tax rate of 24.0%. Austria’s decrease of its 
corporate tax rate down to 23.0% in 2024 is be recognized from 2023 
onwards for deferred taxes. BioNTech USA Holding, LLC is subject to 
Federal Corporate Income Tax (21.0%) as well as State Income Tax in 
various state jurisdictions (effective rate of 4.5%). The deferred tax rates 
calculations basis remained unchanged compared to the previous period.

(in millions €)

Current income taxes

Deferred taxes

Income taxes

Years ended December 31, 

2023

243.1

12.7

255.8

2022

3,629.6

(109.9)

3,519.7

2021

4,535.0

218.9

4,753.9

The following table reconciles the expected income taxes to the income 
tax  expenses.  The  expected  income  taxes  were  calculated  using  the 
combined income tax rate of BioNTech SE applicable to the Group and 
mentioned above which was applied to profit before taxes to calculate the 
expected income taxes.

3 
 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

(in millions €)

Profit before tax

Expected tax credit

Effects 

Years ended December 31, 

2023

1,186.1

321.8

2022

12,954.1

3,529.7

2021

15,046.4

4,622.5

  Deviation due to local tax basis

6.6

8.9

9.1

 Deviation due to deviating 
income tax rate (Germany and 
foreign countries)

  Change in valuation allowance

 Effects from tax losses and  
tax credits

 Change in deferred taxes due 
to tax rate change

  Non-deductible expenses

  Non tax-effective income

 Non tax-effective share-based 
payment expenses

 Tax-effective equity transaction 
costs

  Adjustment prior year taxes

 Non-tax effective bargain 
purchase

  Other effects

Income taxes

Effective tax rate

(0.1)

(14.3)

(66.5)

(2.4)

3.1

(0.6)

7.7

—

5.5

—

(5.0)

255.8

21.6%

7.3

30.6

23.2

(2.3)

2.5

(87.9)

8.7

—

(31.5)

—

30.5

9.4

3.0

19.5

(7.5)

90.5

(0.3)

15.5

(1.2)

(2.9)

(0.7)

(3.0)

3,519.7

            27.2%

4,753.9

31.6%

On November 15, 2018, we established a share option program pursuant 
to which we were permitted to grant selected employees and our Man-
agement Board options to receive shares in the Company. The program 
is designed as an Employee Stock Ownership Plan, or ESOP. We offered 

the participants a certain number of rights, or option rights, subject to their 
explicit acceptance. Grants under the ESOP took place from November 
2018 until December 2019. An exercise of option rights in accordance 
with the terms of the ESOP gives a participant the right to obtain shares 
against payment of the exercise price. By way of an updated decision 
of the Supervisory Board at the end of September 2022 compared to 
the initial settlement mechanism, an ESOP settlement may be made by 
delivery to the participant of such number of ADSs equal to the net value 
of the exercised option rights after deduction of (i) the exercise price and 
(ii) the applicable wage taxes (including solidarity surcharge thereon and 
church tax, if applicable) and social security contributions resulting from 
such exercise. The respective number of ADS shall be settled with ADS 
acquired in the course of the share repurchase program. The applicable 
wage  taxes  (including  solidarity  surcharge  thereon  and  church  tax,  if 
applicable) and social security contributions resulting from such exer-
cise are paid in cash directly to the respective authorities. Expenses for 
taxation purposes resulting from the settlement are only recognized once 
the option rights have been exercised. After considering the settlements 
in the twelve months ended December 31, 2023 and taking into account 
the recognition criteria of IAS 12, a deferred tax is not recognized in our 
consolidated statement of financial position of €17.8 million which relates 
to future settlements.

The current tax savings associated with the excess were directly recog-
nized in equity in a total amount of €19.8 million. Considering these tax 
amounts directly recognized in equity when calculating an effective tax 
rate, the tax rate would be decreased by about 1.6 percentage points. 

The intended settlement mechanism of Option Rights of the Chief Execu-
tive Officer Grant (see Note 16.4 for plan details) led to a deferred tax as-
set in the total amount of €108.8 million as of December 31, 2023. Taking 
into account the recognition criteria of IAS 12 this deferred tax asset is not 
recognized in our consolidated statements of profit or loss neither recog-
nized directly in equity as other reserves in our consolidated statements 
of changes in stockholders’ equity.

3 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Taxes

Deferred taxes for the periods indicated relate to the following:

Year ended December 31, 2023

(in millions €)

Fixed assets

Right-of-use assets

Inventories 

Trade and other receivables 

Lease liabilities

Contract liabilities

Loans and borrowings

Net employee defined benefit liabilities

Share-based payments 

Other provisions

Other (incl. deferred expenses)

Tax losses/tax credits

Deferred tax assets net (before valuation adjustment)

Valuation adjustment

Deferred tax assets/(liabilities), net (after valuation adjustment)

Thereof deferred tax assets

Thereof deferred tax liability

January 1,   
2023

Recognized  
in P&L

Recognized  
in OCI

Recognized directly 
in equity

December 31,  
2023

15.8

(55.8)

148.9

(162.7)

55.2

(10.0)

7.6

0.7

188.4

11.0

61.5

99.5

360.1

(136.7)

223.4

229.6

(6.2)

20.2

(0.8)

(35.3)

72.7

2.0

(33.0)

(2.8)

(0.1)

12.0

(1.2)

(106.4)

(5.1)

(77.8)

65.1

(12.7)

20.8

(33.5)

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

(44.4)

—

—

—

—

—

—

—

(58.3)

—

—

—

(102.7)

(66.4)

(169.1)

(169.1)

—

(8.4)

(56.6)

113.6

(90.0)

57.2

(43.0)

4.8

0.6

142.1

9.8

(44.9)

94.4

179.6

(138.0)

41.6

81.3

(39.7)

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Taxes

Year ended December 31, 2022 

(in millions €)

Fixed assets

Right-of-use assets

Inventories 

Trade and other receivables 

Lease liabilities

Loans and borrowings

Contract liabilities

Net employee defined benefit liabilities

Other provisions

Share-based payments 

Other (incl. deferred expenses)

Tax losses/tax credits

Deferred tax assets net (before valuation adjustment)

Valuation adjustment

Deferred tax assets/(liabilities), net (after valuation adjustment)

Thereof deferred tax assets

Thereof deferred tax liability

January 1,   
2022

Recognized  
in P&L

Recognized  
in OCI

Recognized directly 
in equity

December 31,  
2022

(6.5)

(47.5)

1.8

(95.6)

48.7

23.1

10.6

0.9

6.3

—

1.6

70.9

14.3

(81.0)

(66.7)

229.6

(6.2)

22.3

(8.3)

147.1

(67.1)

6.5

(15.5)

(20.6)

(0.5)

4.7

8.5

59.9

28.6

165.6

(55.7)

109.9

20.8

(33.5)

—

—

—

—

—

—

—

0.3

—

—

—

—

0.3

—

0.3

—

—

—

—

—

—

—

—

—

—

—

179.9

—

—

179.9

—

179.9

(169.1)

—

15.8

(55.8)

148.9

(162.7)

55.2

7.6

(10.0)

0.7

11.0

188.4

61.5

99.5

360.1

(136.7)

223.4

81.3

(39.7)

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

As of December 31, 2023, our accumulated tax losses comprised tax 
losses of German entities that were incurred prior to the establishment 
of a tax group with BioNTech SE or by entities that are not within the tax 
group  (as  of  December  31,  2023:  BioNTech  Real  Estate  Verwaltungs 
GmbH; as of December 31, 2022: BioNTech BioNTainer Holding GmbH, 
BioNTech  Idar-Oberstein  Services  GmbH,  NT  Security  and  Services 
GmbH, BioNTech Real Estate Verwaltungs GmbH and the Real Estate 
partnerships) or U.S. tax group. Up until the year ended December 31, 
2022, our accumulated tax losses also comprised those of the German 
tax group. Our accumulated tax losses for the periods indicated amount-
ed to the following:

(in millions €)

Corporate tax

Trade tax 

(in millions €)

Federal tax credits

State tax credits

Years ended December 31,

2023

260.7

140.1

2022

352.3

204.1

Years ended December 31,

2023

21.3

8.7

2022

4.0

1. 6

2021

272.0

170.6

2021

0.8

0.3

Up until the year ended December 31, 2023, deferred tax assets on tax 
losses were only partially recognized, as there was not sufficient probabil-
ity in terms of IAS 12 that future taxable profits would have been available 
against which all the unused tax losses could have been utilized. 

The amount of deductible temporary differences, unused tax losses, and 
unused tax credits for which no deferred tax asset is recognized in the 
statement of financial position as of December 31, 2023 is €531.5 million. 
Thus  as  of  December  31,  2023,  we  have  not  recognized  deferred  tax 
assets for unused tax losses and temporary differences in an amount 
of €138.0 million (December 31, 2022: €136.7 million 31 December 2021 
€81.0 million).

A reorganization of the intellectual property rights within the Group be-
came effective as of June 30, 2023 and July 1, 2023 which led to deferred 
tax effects in Germany, the U.S. and Austria. As a result, BioNTech SE 
recognized deferred tax assets and deferred tax income at the time of the 
transaction. In addition, this transaction led to a revaluation of previously 
unrecognized U.S. federal and state deferred tax assets, including unused 
tax losses and unused tax credits. As of December 31, 2022, there were 
unrecognized U.S. federal and state deferred tax assets of €128.9 million. 
As of December 31, 2023, it is considered highly probable that taxable 
profits for the U.S. tax group will be available against which the deferred 
tax assets can be utilized in the near future, fulfilling the requirements 
set out by IAS 12. Therefore we no longer continue to maintain the full 
non-recognition of deferred tax assets of our U.S. tax group as there will 
be future taxable profits available against which the unused tax losses 
and  temporary  differences  can  be  utilized.  As  of  December  31,  2023, 
we maintain the non-recognition of deferred tax assets for unused U.S. 
federal and state tax losses and tax credits at an amount of €31.9 million 
and €2.8 million, respectively, as there is not sufficient probability in terms 
of IAS 12 that future taxable income will be available against which these 
unused tax losses can be utilized. The material unrecognized U.S. federal 
and state tax losses and tax credits will begin to expire in 2036. 

3 
 
 
 
 
 
 
 
 
 
 
 
 
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164

The Group does not recognize deferred tax liabilities for taxable tem-
porary differences associated with investments in subsidiaries, in cases 
where the Group is able to control the timing of the reversal of the tempo-
rary difference and it is probable that the temporary differences will not 
reverse in the foreseeable future. The aggregate amount of temporary dif-
ferences associated with investments in subsidiaries, for which deferred 
tax liabilities have not been recognized, is €2.8 million.

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

9 EARNINGS PER SHARE

The following table reflects the income and share data used in the basic 
and diluted EPS calculations:

Basic earnings per share (EPS) is calculated by dividing the profit for the 
year attributable to ordinary equity holders of the parent by the weighted 
average number of ordinary shares outstanding during the year.

Diluted EPS is calculated by dividing the profit attributable to ordinary 
equity holders of the parent by the weighted average number of ordinary 
shares outstanding during the year, plus the weighted average number 
of ordinary shares that would be issued on conversion of all the dilutive 
potential ordinary shares into ordinary shares.

(in millions €,  
except per share data)

Profit attributable to ordinary 
equity holders of the parent  
for basic earnings 

Weighted average number  
of ordinary shares outstanding 
for basic EPS

Effects of dilution from  
share options

Weighted average number  
of ordinary shares outstanding 
adjusted for the effect of dilution 

Earnings per share

Basic earnings for the period  
per share

Diluted earnings for the period 
per share

Years ended December 31, 

2023

2022

2021

930.3

9,434.4

10,292.5

240.6

243.3

244.0

2.1

6.5

15.7

242.7

249.8

259.7

3.87

3.83

38.78

42.18

37.77

39.63

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

10  OTHER INTANGIBLE  

ASSETS AND GOODWILL

Goodwill

(in millions €)

Acquisition costs

As of January 1, 2022

  Currency differences

As of December 31, 2022

As of January 1, 2023

  Acquisition of subsidiaries and businesses

  Currency differences

As of December 31, 2023

Intangible Assets with Indefinite Useful Lives

Goodwill

57.8

3.4

61.2

61.2

306.9

(5.6)

362.5

(in millions €)

Goodwill

Intangible assets with indefinite 
useful life

Total

CGU Immunotherapies

External Product Sales of JPT

External Business of InstaDeep

Total

As of  
December 31, 
2023

As of  
December 31, 
2022

As of  
December 31, 
2023

As of  
December 31, 
2022

As of  
December 31, 
2023

As of  
December 31, 
2022

As of  
December 31, 
2023

As of  
December 31, 
2022

352.2

444.5

796.7

60.7

—

60.7

0.5

—

0.5

0.5

—

0.5

9.8

—

9.8

—

—

—

362.5

444.5

807.0

61.2

—

61.2

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Considering updated financial information regarding our COVID 19 vac-
cine business an additional impairment test for our CGU immunothera-
pies was performed as of December 31, 2023. The recoverable amount 
of the CGU immunotherapies was once again determined based on a fair 
value less cost of disposal (FVLCD), which we derived based on our mar-
ket capitalization as of December 31, 2023. 

As a result of the additional analysis for the CGU immunotherapies, we did 
not identify an impairment for the CGU immunotherapies. Even if our mar-
ket capitalization had been approximately 10% lower, FVLCD would have 
still been above the respective carrying amount of the CGU. 

The intangible assets resulting from licensing and collaboration agree-
ments are combined into one class of assets due to their similar nature 
and use in our operations and are attributed to the CGU immunotherapies.

A  sensitivity  analysis  of  the  key  assumptions,  future  cash  flows  and 
weighted average cost of capital, was performed as part of the scheduled 
impairment testing of the intangible assets not yet available for use. The 
sensitivity analysis did not give rise to any impairment loss, either for a 
reduction of 10% in future cash flows or for a 10% increase in the weighted 
average cost of capital.

For the year ended December 31, 2023, we have total goodwill of €362.5 
million, which relates almost completely to the CGU immunotherapies. 
The CGU immunotherapies focuses on the development of therapies to 
address a range of rare and infectious diseases and comprises our broad 
pipeline that includes mRNA-based immune activators, antigen-targeting 
T cells and antibodies and defined immunomodulators of various immune 
cell mechanisms.

We performed our annual impairment test in October 2023.

The recoverable amount of the CGU immunotherapies has been deter-
mined based on a fair value less cost of disposal (FVLCD), which we derived 
based on our market capitalization as an observable input parameter. 

The recoverable amount of the CGU JPT and the CGU external business 
of InstaDeep has been determined based on the value in use. In assessing 
value in use, the estimated future cash flows, which are derived based on 
the strategic business plan approved by the management, are discounted 
to their present value using a pre-tax discount rate that reflects current 
market assessments of the time value of money and the risks specific to 
the assets. A long-term growth rate of 1.0% is applied to project future 
cash flows after the last year of the detailed planning period.

As a result of the analysis in October 2023, we did not identify an impair-
ment for these CGUs.

Intangible assets with indefinite useful lives mainly comprised intangible 
assets not yet available for use of €443.5 million. Such assets are not 
amortized and therefore reviewed for impairment annually. An impairment 
test was performed on an individual basis of the assets in the fourth quar-
ter of 2023. The recoverable amounts were determined based on value in 
use. The results did not give rise to any impairment losses.

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Other Intangible Assets

(in millions €)

Acquisition costs

As of January 1, 2022

  Additions

  Disposals

  Reclassifications

  Currency differences

As of December 31, 2022

As of January 1, 2023

  Additions

  Acquisition of subsidiaries and businesses

  Disposals

  Reclassifications

  Currency differences

As of December 31, 2023

Concessions, licenses,  
in-process R&D and  
similar rights

Advance  
payments

191.6

22. 8

(0.1)

6.1

1.9

222.3

222.3

489.2

187.4

(1.6)

4.9

(3.6)

898.6

7.8

11. 4

—

(6.1)

—

13.1

13.1

15.8

—

(1.6)

(4.9)

—

22.4

Total

199.4

34.2

(0.1)

—

1.9

235.4

235.4

505.0

187.4

(3.2)

—

(3.6)

921.0

Continued on next page

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Other Intangible Assets

(in millions €)

Cumulative amortization and impairment charges

As of January 1, 2022

  Amortization

  Disposals

  Currency differences

As of December 31, 2022

As of January 1, 2023

  Amortization

  Disposals

  Currency differences

As of December 31, 2023

(in millions €)

Carrying amount

As of December 31, 2022

As of December 31, 2023

Concessions, licenses,  
in-process R&D and  
similar rights

Advance  
payments

54.8

22.0

(0.1)

0.2

76.9

76.9

40.5

(0.3)

(0.2)

116.9

—

—

—

—

—

—

—

—

—

—

Concessions, licenses,  
in-process R&D and  
similar rights

145.4

781.7

Advance  
payments

13.1

22.4

Total

54.8

22.0

(0.1)

0.2

76.9

76.9

40.5

(0.3)

(0.2)

116.9

Total

158.5

804.1

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The increase in other intangible assets by €645.6 million from December 
31, 2022 to December 31, 2023 was mainly related to the acquisition of 
InstaDeep (see Note 5) and licenses fulfilling the definition of identifiable 
assets acquired. We entered into license and collaboration agreements 
in which we work together with partners to develop pharmaceutical prod-
ucts and, provided regulatory approval is granted, commercialize them. 
The upfront payments in connection with the license and collaboration 
agreements described below resulted in the recognition of intangible 
assets not yet available for use in the amount of €443.5 million and a pre-
payment for future development activities recognized in the other non- 
financial assets (€22.5 million as at December 31, 2023, see also Note 14). 

In March 2023, we entered into license and collaboration agreements 
with Duality Biologics (Suzhou) Co. Ltd., Shanghai, China, or Duality, for 
exclusive licenses to two investigational ADC assets (BNT323/DB-1303 
and  BNT324/DB-1311)  directed  against  targets  expressed  in  a  broad 
range of human cancers. In August 2023, we signed another exclusive 
agreement with Duality to develop, manufacture and commercialize an 
additional ADC, BNT325/DB-1305. Duality received upfront payments 
totaling $220.0 million (€203.7 million) and is eligible to receive future 
milestone payments as well as tiered royalties.

In April 2023, we entered into a licensing and collaboration agreement 
with OncoC4 Inc., Rockville (Maryland), United States, or OncoC4, which 
includes joint development of BNT316/ONC-392 in a range of solid tumor 
indications, with the parties equally sharing development costs for such 
joint development studies. BioNTech holds the exclusive worldwide com-
mercialization rights for this product candidate. OncoC4 received an up-
front payment of $200.0 million (€181.5 million, thereof €125.2 million paid 
for the acquisition of an intangible asset) and is eligible to receive future 
milestone payments as well as tiered royalties.

In November 2023, we entered into a strategic research collaboration 
and worldwide license agreement with MediLink Therapeutics (Suzhou) 
Co., Ltd., or MediLink Therapeutics, for the development of a next-gen-
eration ADC, BNT326/YL202, against Human Epidermal Growth Factor 
Receptor 3 (HER3). MediLink Therapeutics received an upfront payment 
of $70.0 million (€64.1 million) and is eligible to receive future milestone 
payments as well as tiered royalties.

In December 2023, we entered into an exclusive global license and col-
laboration with Biotheus Inc., or Biotheus, under which we will be devel-
oping, manufacturing and commercializing Biotheus’ bispecific antibody 
candidate BNT327/PM8002 globally ex-Greater China. We agreed to an 
upfront payment of $55.0 million (€50.6 million) plus future milestone and 
royalty payments.

In July 2023, in connection with the acquisition of InstaDeep we acquired 
DeepChain technology. As of December 31, 2023 the book value of Deep-
Chain technology amounted to €163.3 million with a remaining useful life 
of 6.6 years.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

11  PROPERTY, PLANT AND  

EQUIPMENT

(in millions €)

Acquisition and production costs

As of January 1, 2022

  Additions

  Disposals

  Reclassifications

  Currency differences

As of December 31, 2022

As of January 1, 2023

  Additions

  Acquisition of subsidiaries and businesses

  Disposals

  Reclassifications

Currency differences

As of December 31, 2023

Land and  
buildings

Equipment, tools  
and installations

Construction in progress 
and advance payments

104.1

100.2

—

12.0

0.7

217.0

217.0

9.7

—

—

9.3

(0.6)

235.4

198.3

46.7

(1.1)

28.2

0.9

273.0

273.0

50.3

2.1

(2.4)

22.3

(1.2)

344.1

94.3

182.3

(0.5)

(40.2)

(0.4)

235.5

235.5

189.4

—

(0.2)

(31.6)

(3.6)

389.5

Total

396.7

329.2

(1.6)

—

1.2

725.5

725.5

249.4

2.1

(2.6)

—

(5.4)

969.0

Continued on next page

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

PROPERTY, PLANT AND  
EQUIPMENT 

(in millions €)

Cumulative depreciation and impairment charges

Land and  
buildings

Equipment, tools  
and installations

Construction in progress 
and advance payments

As of January 1, 2022

  Depreciation 

  Disposals

  Currency differences

As of December 31, 2022

As of January 1, 2023

  Depreciation 

  Disposals

  Currency differences

As of December 31, 2023

(in millions €)

Carrying amount

As of December 31, 2022

As of December 31, 2023

14.2

7.8

—

—

22.0

22.0

14.4

—

(0.2)

36.2

60.0

34.6

(0.4)

0.1

94.3

94.3

83.3

(1.7)

(0.3)

175.6

—

—

—

—

—

—

—

—

—

—

Land and  
buildings

Equipment, tools  
and installations

Construction in progress 
and advance payments

195.0

199.2

178.7

168.5

235.5

389.5

Total

74.2

42.4

(0.4)

0.1

116.3

116.3

97.7

(1.7)

(0.5)

211.8

Total

609.2

757.2

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Non-Current Assets by Region

As of December 31, 2023, non-current assets comprised €158.2 million  
in  other  intangible  assets,  goodwill,  property,  plant  and  equipment,  
right-of-use assets and other assets of our subsidiaries incorporated 
in the United States (as of December 31, 2022: €188.0 million) as well 
as €511.7 million in the United Kingdom (as of December 31, 2022: nil), 
respectively. The remaining non-current assets of €1,469.0 million (as of 
December 31, 2022: €871.9 million) mainly relate to entities incorporated 
in Germany.

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

12  FINANCIAL ASSETS AND  
FINANCIAL LIABILITIES

In general, the aim is to protect and maximize the financial resources  
available for further research and development projects.

Since December 1, 2021, we have an investment and asset management 
policy in place that contains policies and processes for managing cash 
and cash equivalents. Under this policy, our investment portfolio is to be 
maintained in a manner that minimizes risks to the invested capital. These 
risks include mainly credit risk and concentration risk. The portfolio must 
provide  liquidity  in  a  timely  manner  to  accommodate  operational  and  
capital needs. The portfolio is managed by the Treasury department.

12.1 Capital Risk Management

Our capital management objectives are designed primarily to finance our 
growth strategy.

We are not subject to externally imposed capital requirements. Our capital 
management objectives were achieved in the years ended December 31, 
2023, and 2022.

Our  treasury  committee  reviews  the  total  amount  of  cash  and  cash  
equivalents on a regular basis. As part of this review, the committee con-
siders total cash and cash equivalents, cash outflow, currency translation 
differences and refinancing activities. We monitor cash using a burn rate. 
The cash burn rate is defined as the average monthly net cash flow from 
operating and investing activities during a financial year.

(in millions €)

December 31, 2023

December 31, 2022

Cash at banks and on hand

Cash equivalents

  Bank deposits

  Money market funds

  Reverse Repo

Total

453.1

11,210.6

2,589.5

7,446.1

1,175.0

11,663.7

1,325.2

12,549.9

9,401.0

3,148.9

—

13,875.1

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

12.2 Categories of Financial Instruments

Financial Assets and Liabilities at Amortized Cost and at Fair Value through 
OCI and Profit or Loss

Set out below is an overview of financial assets and liabilities at amortized 
cost and at fair value through OCI and profit or loss, as of the dates indicated:

December 31, 2023  

(in millions €)

Financial assets measured at fair value

  Money market funds

  Non-listed equity investments

  Listed equity investments

Financial assets not measured at fair value

  Trade and other receivables 

  Security investments

  Other financial assets

  Bank deposits

  Reverse Repo

  Cash at banks and on hand

Financial liabilities measured at fair value

  Foreign exchange forward contracts

  Contingent consideration

Financial liabilities not measured at fair value

  Lease liabilities

  Loans and borrowings

  Trade payables and other payables

  Other financial liabilities

Category (1)

Carrying 
amount

Level 1  
(Fair value)

Level 2  
(Fair value)

Level 3  
(Fair value)

FVTPL

FVTOCI

FVTOCI

AC

AC

AC

AC

AC

AC

FVTPL

FVTPL

n/a

AC

AC

AC

7,446.1

7,446.1

27.1

26.0

2,155.7

5,989.7

18.6

2,589.5

1,175.0

453.1

0.4

38.8

216.7

2.3

354.0

414.9

—

26.0

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

0.4

—

—

—

—

—

—

27.1

—

—

—

—

—

—

—

—

38.8

—

—

—

—

Total

7,446.1

27.1

26.0

2,155.7

5,989.7

18.6

2,589.5

1,175.0

453.1

0.4

38.8

216.7

2.3

354.0

414.9

(1)  Financial assets and liabilities categorized at amortized costs mainly correspond to fair value. Fair values 

are not disclosed because the book values represent a reasonable approximation of fair value. We do not 

make a disclosure for cash and cash equivalents, trade receivables and trade payables. 

Continued on next page

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

December 31, 2022  

(in millions €)

Financial assets measured at fair value

  Foreign exchange forward contracts

  Money market funds

  Non-listed equity investments

  Listed equity investments

Financial assets not measured at fair value

  Trade and other receivables 

  Other financial assets

  Bank deposits

  Cash at banks and on hand

Financial liabilities measured at fair value

  Contingent consideration

Financial liabilities not measured at fair value

  Lease liabilities

  Loans and borrowings

  Trade payables and other payables

  Other financial liabilities

Category (1) Carrying amount

Level 1  
(Fair value)

Level 2  
(Fair value)

Level 3  
(Fair value)

Total

FVTPL

FVTPL

FVTOCI

FVTOCI

AC

AC

AC

AC

183.7

3,148.9

57.1

20.0

7,145.6

8.8

9,401.0

1,325.2

FVTPL

6.1

n/a

AC

AC

AC

210.1

2.1

204.1

785.1

—

3,148.9

—

20.0

—

—

—

—

—

—

—

—

—

183.7

—

57.1

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

6.1

—

—

—

—

183.7

3,148.9

57.1

20.0

7,145.6

8.8

9,401.0

1,325.2

6.1

210.1

2.1

204.1

785.1

(1)  Financial assets and liabilities categorized at amortized costs mainly correspond to fair value. We do not 

make a disclosure for cash and cash equivalents, trade receivables and trade payables. Fair values are 

disclosed because the book values represent a reasonable approximation of fair value.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Equity investments designated at Fair Value through OCI

Measurement of fair values

Financial investments in equity securities measured at fair value through 
other comprehensive income comprise the following effects:

The following table shows the valuation techniques used in measuring fair 
values for financial instruments in our consolidated statements of financial 
position, as well as the significant unobservable inputs used. 

(in millions €)

December 31, 2023

December 31, 2022

Type

Valuation technique

Net gain on equity instruments designated 
at fair value through other comprehensive 
income

Total

3.7

3.7

10.5

10.5

Forward exchange  
contracts

Non-listed equity  
investments

Listed equity  
investments

Money market funds

Contingent  
consideration

Discounted cash flow using 
par method. Expected future 
cash flows based on foreign 
exchange forwards  
discounted over the 
respective remaining term 
of the contracts using the 
respective deposit interest 
rates and spot rates.

Quantitative and qualitative 
factors such as actual and 
forecasted results, cash 
position and financing round 
valuations.

Significant  
unobservable inputs

n/a

  Actual and forecasted 
results

  Cash position

  Nature and pricing indication 
of latest financing round

Stock prices of the listed 
companies and applicable 
exchange rates, if the listing 
is in a foreign currency.

n/a

Quoted prices on an active 
market

n/a

Present value of expected 
future payments and reflecting 
changes in expected 
achievement of underlying 
performance parameters 
and compounding effects. 

  Expected future payments

  Applied cost of capital

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

12.3 Recurring Fair Values (Level 3)

12.4  Financial Instruments Risk Management Objectives 

and Policies

The following table shows the recurring fair value measurement of the 
contingent considerations and the effect of the measurements on our 
consolidated statements of profit or loss for the current period.

(in millions €)

As of January 1, 2022

As of January 1, 2023

  Purchases

Net effect on profit or loss

  Net change in fair value

As of December 31, 2023

Contingent  
consideration

6.1

6.1

31.8

0.9

38.8

The sensitivity of the fair values of contingent considerations in fair value 
level 3 to the significant, unobservable, variable input factors, with all other 
factors remaining constant, is shown in the following table:

Contingent consideration

Input factor

Cash flow projections

Discount rate

Change in  
assumptions

10%

1%

Change in fair value 
with increasing  
input factor  
(in millions €)

Change in fair value 
with decreasing 
input factor  
(in millions €)

3.4

(0.8)

(3.4)

0.8

The estimated fair value of non-listed equity investments would, for exam-
ple, increase (decrease) if price of latest financing round were to increase 
(decrease) and the overall company value were higher (lower).

Our financial liabilities mainly comprise obligations derived from license 
agreements, trade and other payables, lease liabilities, contingent consid-
eration, loans and borrowings, hedging liabilities as well as other financial 
liabilities. The main purpose of these financial liabilities is to enable our 
operations. Our principal financial assets include mainly cash, security in-
vestments and trade receivables that derive directly from our operations.

We are exposed to market risk, credit risk and liquidity risk. Our Manage-
ment Board oversees the management of these risks. 

The treasury committee provides assurance to our Management Board 
that  our  financial  risk  activities  are  governed  by  appropriate  policies 
and  procedures  and  that  financial  risks  are  identified,  measured  and  
managed  in  accordance  with  our  policies  and  risk  objectives.  The  
Management Board reviews and agrees policies for managing each of 
these risks, which are summarized below.

12.5 Market Risks

Market risks address the risks that the fair value or future cash flows of a 
financial instrument will fluctuate due to changes in market prices. Market 
risks comprise three types of risk: interest risks, foreign currency risks 
and other price risks. Financial instruments affected by market risks in-
clude financial assets such as security investments, trade and other re-
ceivables, cash and cash equivalents as well as financial liabilities such as 
trade payables and other financial liabilities. We do not consider interest 
risks as well as other price risks as material risks to us.

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

There were no material changes in the way the risks were managed and 
valued during the years ended December 31, 2023, and 2022. Because 
of the significantly higher cash balance and security investments – the 
market risk exposure on counterparty risk increased compared to the 
previous period.

Foreign Currency Risks

Foreign currency risks address the risks that the fair value or future cash 
flows  of  an  exposure  will  fluctuate  because  of  changes  in  foreign  ex-
change rates. We are subject to currency risks, as our income and ex-
penditures are denominated in Euro and the U.S. dollar. As such, we are 
exposed to exchange rate fluctuations between these currencies. Cash 
inflows  denominated  in  U.S.  dollar  mainly  result  from  generating  pro-
ceeds under our collaboration agreements. Our commercial revenues are  
primarily collaboration revenues from earnings based on our partners’ 
gross profit, which is shared under the respective collaboration agree-
ments and represents payments we receive in U.S. dollar. Cash outflows 
dominated in U.S. dollar mainly result from amounts spent on research 
and development activities and license obligations as well as expanding 
our global footprint further. With the aim of preserving capital, surplus 
liquidity is mainly invested in domestic currency investments as exchange 
rate fluctuations can reduce the value of our financial positions. We limit 
the effects of the identified risks by means of a coordinated and con-
sistently implemented risk strategy. Besides applying natural hedging 
relationships where possible, foreign exchange forward contracts are 
concluded, as a matter of principle, as instruments to mitigate foreign 
currency exchange risk associated with foreign currency-denominated 
payments. However, the foreign exchange forward contracts which we 
entered into were not designated as hedging instruments under IFRS.

The carrying amount of the monetary assets and liabilities denominated in 
U.S. dollar at the dates indicated are as follows:

(in millions €)

December 31, 2023

December 31, 2022

Cash and cash equivalents in U.S. dollar

Monetary assets in U.S. dollar

Monetary liabilities and provisions  
in U.S. dollar

Total

122.6

1,191.9

567.3

747.2

1,487.4

7,098.5

1,527.8

7,058.1

The following tables demonstrate the sensitivity to a reasonable, possible 
change in U.S. dollar exchange rates or U.S. dollar forward rates, with all 
other variables held constant. The impact on our profit before tax is due to 
changes in the fair value of monetary assets and liabilities. The exposure 
to foreign currency changes for all other currencies is not material.

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

1 € =

Currency

U.S. dollar

(in millions €)

2023

2022

Closing rate

Average rate

Country

United States 

2023

1.1050

2022

1.0666

2023

1.0813

2022

1.0530

Change  
in U.S. dollar rate

Effect on profit/ 
(loss) before tax

Effect on  
pre-tax equity

+5%

-5%

+5%

-5%

(35.5)

39.2

(195.2)

215.7

(35.5)

39.3

(191.5)

211.7

12.6  Credit Risk Management

Credit risks address the risks that a counterparty will not meet its obli-
gations under a financial instrument or customer contract, leading to a 
financial loss. We are exposed to credit risks from our operating activities, 
including  security  investments,  bank  deposits,  reverse  repos,  foreign 
exchange transactions, trade and other receivables and cash at banks. 
The maximum exposure to credit risk for the components of the con-
solidated statements of financial position as of December 31, 2023, and  
December 31, 2022, are the carrying amounts as illustrated in Note 12.1  
and Note 12.2.

Security Investments, Bank Deposits, Reverse Repos and Cash at banks

Our financial management is dedicated predominantly to the goal of cap-
ital preservation. Thus, all our financial activities are focused towards 
avoiding risks and, where they cannot be avoided, actively managing and 
minimizing them. Credit risks from balances with security investments, 
bank  deposits,  reverse  repos  and  cash  at  banks  are  managed  by  our 
Treasury department in accordance with our investment and asset man-
agement policy.

Our security investments are solely invested in the highest-quality liq-
uid  assets  (e.g.  core  European  sovereign,  supranational  and  agency 
bonds) and bank deposits with a maturity of more than 3 months (held at  
selected banks, exclusively rated as investment grade). They do not bear 
any currency risks or material credit risks. The bank deposits are held at 
selected banks, exclusively rated as investment grade. We limit our invest-
ment engagements individually and track each credit risk continuously.  
For reverse repos, only investment-grade counterparties qualify as our 
business partners and even secured investments are solely collateralized 
by high-quality liquid assets.

Accordingly, credit risks from these financial assets are limited. Before 
entering into new business relationships and during ongoing business 
relationships, we evaluate our business partners with regard to their indi-
vidual default risk. Therefore, we do not presume an increased credit risk 
as of the balance sheet date and determine the impairment loss based on 
the upcoming twelve months.

The calculated expected credit losses were not material as of December  
31, 2023, and December 31, 2022. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Trade and Other Receivables

12.7  Liquidity Risk

Our exposure to credit risks of trade and other receivables is primarily re-
lated to transactions with corporate customers in the biopharma/biotech 
industry that operate in the United States or Germany, as well as govern-
ments which are customers, in connection with fulfilling our commercial 
obligations in our territories as defined in our contracts with customers. 
An analysis of the aging of receivables and the creditworthiness of cus-
tomers is used to evaluate this risk at each reporting date. We follow risk 
control procedures to assess the credit quality of our customers taking 
into account their financial position, past experience and other factors.

We plan to invest heavily in R&D as we make a strong drive to build out our 
global development organization and diversify our therapeutic area foot-
print. Additionally, we plan to enhance capabilities through complemen-
tary acquisitions, technologies, infrastructure and manufacturing. Our 
liquidity management ensures the availability of cash and cash equiva-
lents, short term financial instruments for operational activities and further 
investments through appropriate budget planning. In addition, a sufficient 
level of cash and cash equivalents, which are managed centrally, is always 
maintained to finance the operational activities.

As of December 31, 2023, outstanding trade and other receivables were 
mainly due from  our  collaboration  partner Pfizer. Besides  well-estab-
lished pharmaceutical companies and governmental institutions, our oth-
er customers – to a smaller extent – are medical universities, other public 
institutions and peers in the biopharma industry, which have good credit 
ratings. Due to this customer portfolio, the credit risk on trade and other 
receivables is generally very low. We have not incurred material bad debt 
expense and do not expect that this will change with respect to the trade 
and other receivables outstanding as of December 31, 2023. 

We monitor liquidity risks using a liquidity planning tool.

Ultimately, the responsibility for liquidity risk management lies with our 
Management Board, which has established an appropriate approach to 
managing short-, medium- and long-term financing and liquidity require-
ments. We manage liquidity risks by holding appropriate reserves based 
on our COVID-19 sales, as well as by monitoring forecasted and actual 
cash flows and reconciling the maturity profiles of financial assets and 
liabilities. Significant reserves currently exist and were generated during 
the Covid-19 pandemic.

The expected credit risk on trade and other receivables derived from  
applying the simplified approach in calculating expected credit losses 
was not material as of December 31, 2023, and December 31, 2022. 

Risk Concentration

Concentrations arise when the number of counterparties is small or when 
a larger number of counterparties is engaged in similar business activi-
ties, or activities in the same geographical region, or has economic fea-
tures that would cause their ability to meet contractual obligations to be  
affected similarly by changes in economic, political or other conditions. 
Concentrations indicate the relative sensitivity of our performance to de-
velopments affecting a particular industry. We only have a limited number 
of customers mainly comprising pharmaceutical companies and govern-
mental institutions.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The maturity profile of our financial liabilities based on contractual undis-
counted payments is summarized as follows:

Year ended December 31, 2023  

(in millions €)

Loans and borrowings

Trade and other payables

Lease liabilities

Contingent consideration

Foreign exchange forward contracts

Other financial liabilities

Total

Year ended December 31, 2022  

(in millions €)

Loans and borrowings

Trade and other payables

Lease liabilities

Contingent consideration

Other financial liabilities

Total

Less than 1 year

1 to 5 years

More than 5 years

—

354.0

34.1

—

0.4

414.9

803.4

2.3

—

136.6

57.5

—

—

196.4

—

—

73.7

0.3

—

—

74.0

Less than 1 year

1 to 5 years

More than 5 years

—

204.1

40.5

—

785.1

1,029.7

2.1

—

112.9

—

—

115.0

—

—

79.1

6.1

—

85.2

Total

2.3

354.0

244.4

57.8

0.4

414.9

1,073.8

Total

2.1

204.1

232.5

6.1

785.1

1,229.9

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

12.8  Changes in Liabilities Arising  
from Financing Activities

Year ended December 31, 2023  

(in millions €)

Current obligations under lease contracts

Non-current obligations under lease contracts

Loans and borrowings

Total

Year ended December 31, 2022  

(in millions €)

Current obligations under lease contracts

Non-current obligations under lease contracts

Loans and borrowings

Convertible note – embedded derivative

Total

January 1,  
2023

36.0

174.1

2.1

212.2

January 1,  
2022

27.9

153.7

119.9

308.7

610.2

Cash flows

and disposals Reclassification

Other

New leases  

December 31, 
2023

(40.3)

—

0.2

(40.1)

(0.6)

51.1

—

50.5

34.1

(34.1)

—

—

(1.1)

(2.5)

—

(3.6)

28.1

188.6

2.3

219.0

Cash flows

and disposals Reclassification

Other

New leases  

December 31, 
2022

(41.1)

—

(18.0)

—

(59.1)

14.8

52.6

—

—

67.4

33.3

(33.3)

—

—

—

1.1

1.1

(99.8)(1)

(308.7)(1)

(406.3)

36.0

174.1

2.1

—

212.2

(1)  Related to the early redemption of our convertible note during the year ended December 31, 2023,  

as further described in Note 15.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

13 INVENTORIES

(in millions €)

December 31, 2023

December 31, 2022

Raw materials and supplies

Unfinished goods

Finished goods

Total

347.5

4.0

6.2

357.7

409.7

21.0

8.9

439.6

During  the  year  ended  December  31,  2023  expenses  from  inventory  
write-downs to net realizable value due to inventories expected to be 
unsellable,  not  fulfilling  the  specification  defined  by  our  quality  stan-
dards, shelf-life expiry or disposals resulted in €94.5 million, compared to  
€484.6  million  in  the  previous  period.  The  inventories  valued  at  net  
realizable value in our consolidated statements of financial position as of 
December 31, 2023, take contractual compensation payments into con-
sideration. We have not pledged any inventories as securities for liabilities. 
During the years ended December 31, 2023, and 2022, costs of inven-
tories in the amount of €354.4 million and €1,550.6 million, respectively, 
were recognized as cost of sales. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

14 OTHER NON-FINANCIAL ASSETS

(in millions €)

Deferred expenses

Sales tax receivable

Prepayments related  
to CRO and CMO contracts

Other

Total

Total current

Total non-current

December 31, 2023

December 31, 2022

313.2

5.2

—

45.9

364.3

280.9

83.4

120.0

93.8

35.3

29.3

278.4

271.9

6.5

Deferred expenses mainly comprise prepayments for future expenses 
of €151.1 million (nil as of December 31, 2022) for the settlement fee of the 
European Commission to our collaboration partner and prepayments 
for our collaborations with OncoC4 Inc., Rockville, USA, €22.5 million 
(nil as of December 31, 2022), Ryvu Therapeutics S.A., Krakau, Poland, 
€15.7  million  (€19.7  million  as  of  December  31,  2022)  and  Medigene  
Immunotherapies GmbH, Planegg/Martinsried, €5.1 million (€9.4 million 
as of December 31, 2022). Prior year deferred expenses mainly comprise 
service contracts and insurance obligations.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

15 ISSUED CAPITAL AND RESERVES

As  of  December  31,  2023,  the  number  of  shares  outstanding  was 
237,725,735. This amount excludes 10,826,465 shares held in treasury. 
For the year ended December 31, 2022, the number of shares outstand-
ing was 243,215,169, excluding 5,337,031 shares held in treasury.

Capital Transactions During the Year Ended December 31, 2023

In March 2022, our Management Board and Supervisory Board autho-
rized the 2022 share repurchase program of ADSs, pursuant to which 
we were permitted to repurchase ADSs, each representing one ordinary 
share, with a value of up to $1.5 billion a two-year period, commencing on 
May 2, 2022. The first tranche of our 2022 share repurchase program of 
ADSs, with a value of up to $1.0 billion, concluded on October 10, 2022. 
The  second  tranche  with  a  value  of  up  to  $0.5  billion  commenced  on  
December 7, 2022 and concluded on March 17, 2023.

The following repurchases under the programs occurred:

2022 Program first tranche ($1.0 billion)   

Period

May 2022

June 2022

July 2022

August 22

September 22

October 2022

Total

Number of  
ADSs purchased

917,988

1,160,219

519,320

1,666,515

2,280,988

400,483

6,945,513

Average price paid  
per ADS

$151.76 (€143.99)

$140.82 (€133.35)

$162.03 (€159.40)

Net amount spent  
(in millions)

$139.3 (€132.2)

$163.4 (€154.7)

$84.1 (€82.8)

$149.08 (€148.24)

$248.4 (€247.0)

$135.95 (€137.66)

$136.37 (€139.09)

$310.1 (€314.0)

$54.6 (€55.7)

$999.9 (€986.4)

Continued on next page

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

2022 Program second tranche ($0.5 billion)  

Period

January 2023

February 2023

March 2023

Total

Number of  
ADSs purchased

618,355

857,620

745,196

2,221,171

Average price paid  
per ADS

$142.26 (€131.12)

$138.05 (€129.06)

$128.49 (€121.08)

Net amount spent  
(in millions)

$88.0 (€81.1)

$118.4 (€110.7)

$95.7 (€90.2)

$302.1 (€282.0)

In March 2023, our Management Board and Supervisory Board autho-
rized the 2023 share repurchase program, under which we were per-
mitted to purchase ADSs, each representing one ordinary share, with a 
value of up to $0.5 billion, which started June 2, 2023 and concluded on 
September 18, 2023. 

The following repurchases under the programs occurred:

Program 2023 ($0.5 billion)  

Period

June 2023

July 2023

Aug 23

Sep 23

Total

Number of  
ADSs purchased

1,532,685

1,738,061

1,261,706

114,513

4,646,965

Average price paid  
per ADS

$108.92 (€100.45)

$107.92 (€97.57)

$105.07 (€95.85)

$112.22 (€105.07)

Net amount spent  
(in millions)

$166.9 (€154.0)

$187.6 (€169.6)

$132.6 (€120.9)

$12.9 (€12.0)

$500.0 (€456.5) 

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188

In June 2022, at the Annual General Meeting, our shareholders approved 
the proposed special cash dividend of €2.00 per ordinary share (including 
those held in the form of ADSs), which led to an aggregate payment of 
€484.3 million.

In November and December 2022, the ESOP 2018 and LTI-plus awards 
were settled by transferring ordinary shares previously held in treasury to 
the entitled employees and Management Board members (see Note 16).

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Capital Transactions During the Year Ended December 31, 2022

In  January  2022,  we  announced  a  new  research,  development  and  
commercialization collaboration with Pfizer to develop potentially the first 
mRNA-based vaccine for the prevention of shingles (herpes zoster virus, 
or HZV). In connection with this collaboration, Pfizer agreed to make an 
equity investment in us, acquiring 497,727 ordinary shares paying a total 
amount of €110.6 million. The issuance of 497,727 ordinary shares with 
the nominal amount of €0.5 million was registered with the commercial 
register (Handelsregister) on March 24, 2022. The equity investment, 
which was issued in a foreign currency, represents a derivative from the 
date of signing until the date of closing of the transaction. From the fair 
value measurement of this derivative, €43.0 million were recognized in 
finance income in our consolidated statements of profit or loss during the 
year ended December 31, 2022. At the closing date, in February 2022, 
this derivative and the agreed investment amount were recognized in our 
capital reserve and, taking an increase in share capital of €0.5 million into 
account, led to a net increase of the capital reserve of €67.1 million in our 
consolidated statements of financial position.

In March 2022, we redeemed our convertible note by exercising our early 
redemption option (see Note 12), which was fulfilled in April 2022, by is-
suing 1,744,392 ordinary shares. The nominal amount of €1.8 million was  
recorded in share capital and, finally, as a result of the transaction, the 
capital reserve increased by €233.2 million in our consolidated state-
ments of financial position. The declaratory registration with the commer-
cial register (Handelsregister) was made on May 20, 2022.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

16 SHARE-BASED PAYMENTS

During the years ended December 31, 2023, 2022, and 2021, our share-
based payment arrangements led to the following expenses: 

(in millions €)

Note

2023

Expense arising from equity-settled share-based payment arrangements

  Employee Stock Ownership Plan

  Chief Executive Officer Grant

  Management Board Grant (1)

 BioNTech 2020 Employee Equity Plan for Employees Based Outside 
North America

InstaDeep Employee Incentive Plan (2)

Expense/(Income) arising from cash-settled share-based payment 
arrangements

  Employee Stock Ownership Plan

  Management Board Grant (1)

  BioNTech Restricted Stock Unit Plan for North America Employees

16.5

16.4

16.3

16.1

16.5

 16.2, 16.3

16.1

Total

Cost of sales

Research and development expenses

Sales and marketing expenses

General and administrative expenses 

Total

44.1

—

1.2

3.2

36.3

3.4

7.3

(0.9)

(2.4)

10.6

51.4

6.5

33.4

1.0

10.5

51.4

Years ended December 31,

2022

46.5

13.8

3.1

4.3

25.3

—

61.5

53.4

—

8.1

108.0

3.0

84.6

0.8

19.6

108.0

2021

61.0

20.2

5.9

2.4

32.5

—

32.7

6.3

3.6

22.8

93.7

7.0

60.5

0.5

25.7

93.7

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

(1) 

In May 2021 and 2022, phantom options were granted under the Management Board Grant for the years 

2021 and 2022 which led to a modification from an equity-settled to cash-settled share-based payment 

arrangement and a reclassification of €1.1 million and €3.3 million between equity and non-current other 
liabilities, respectively. Expenses incurred before and after the modification dates have been disclosed  

as equity-settled or cash-settled share-based payment arrangement, respectively. The amount includes  

expenses incurred with respect to a one-time signing bonus granted to Jens Holstein as of his appointment 
to the Management Board (see Note 21.2). 

(2)  As part of the acquisition of InstaDeep (see Note 5), it was agreed to issue long-term equity awards with 
a total target incentive value of £15.0 million, each for options and RSUs. The allocation shall be made in a 

manner consistent with BioNTech's existing share-based payment arrangements. The arrangement was 

communicated to the employees as part of the acquisition but relates to future services. Following the 

rules of IFRS 2, starting with the service commencement date during the year ended December 31, 2023 

and in advance of the grant date, expenses were recorded based on the estimated grant date fair values 

and numbers of equity instruments. 

During the years ended December 31, 2023, 2022 and 2021, our share-
based payment arrangements led to a cash outflow of €766.2 million, 
€51.8 million and €13.4 million, respectively. We expect to settle the equi-
ty-settled share-based payment arrangements of our 2020 Management 
Board Grant (see Note 16.3), the Chief Executive Officer Grant (see Note 
16.4) and the Employee Stock Ownership Plan (see Note 16.5) on a net 
basis by delivering to the participant a number of ADSs equal to the net 
value of the exercised option rights after deduction of (i) the exercise price 
and (ii) the applicable wage taxes (including solidarity surcharge thereon 
and church tax, if applicable) and social security contributions resulting 
from such exercise. This reduces the dilutive impact of the respective 
rights compared to an all-equity settlement. If all of the equity-settled 
rights outstanding as of December 31, 2023, were to be exercised ac-
cordingly, the cash outflow to the tax authority in 2024 would amount 
to approximately €213.0 million (based on the share price as of Decem-
ber 31, 2023).

16.1 BioNTech Employee Equity Plan

BioNTech 2020 Employee Equity Plan for Employees Based Outside 
North America (Equity-Settled)

Description of Share-Based Payments
In December 2020, we approved the BioNTech 2020 Employee Equity 
Plan for employees based outside North America, or the European Plan. 
Under the European Plan, Restricted Stock Units, or RSUs, are offered to 
our employees. 

Award  agreements  were  entered  as  of  the  respective  grant  dates  in  
February 2021 (LTI 2020 and LTI-plus program), January 2022 (LTI 2021 
program) and December 2022 (LTI 2022 program). RSUs issued under 
the  LTI  2020,  LTI  2021  and  LTI  2022  programs  vest  annually  in  equal 
installments over respective waiting periods of four years, commencing 
in December 2020, December 2021 and December 2022, respectively. 
RSUs issued under the LTI-plus program vested annually in equal install-
ments over the waiting period of two years, which elapsed in December 
2022. Hence, during the year ended December 31, 2022, the LTI-plus 
awards were settled by transferring shares previously held in treasury, 
see Note 15. All programs were classified as equity-settled as we have the 
ability to determine the method of settlement. 

Measurement of Fair Values
The fair values of the awards issued under the European Plan were based 
upon the price of our ADSs representing ordinary shares at the grant date. 

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Reconciliation of Outstanding Share-Options

As of January 1, 2022

Forfeited/Modified

Granted/Allocated

Settled (1)

As of December 31, 2022

As of January 1, 2023

Forfeited/Modified

As of December 31, 2023

Thereof vested

Thereof unvested

LTI-plus program

LTI 2020 program

LTI 2021 program

LTI 2022 program

372,011

(7,932)

—

(364,079)

—

—

—

—

—

—

242,416

(7,111)

—

—

235,305

235,305

(4,400)

230,905

175,523

55,382

110,036

(5,428)

—

—

104,608

104,608

(3,497)

101,111

51,905

49,206

—

—

396,11

—

396,11

396,11

(16,141)

379,969

96,466

283,503

(1)  The closing price of an American Depositary Share of BioNTech on Nasdaq on December 15, 2022, the 

settlement date, converted from USD to Euro using the exchange rate published by the German Central 

Bank (Deutsche Bundesbank) on the same day was €171.40.

Inputs Used in Measurement of the Fair Values at Grant Dates

Weighted average fair value

Waiting period (in years)

LTI-plus program

LTI 2020 program

LTI 2021 program

LTI 2022 program

87.60

2.0

92.21

4.0

203.22

4.0

165.03

4.0

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

BioNTech 2020 Restricted Stock Unit Plan 
for North America Employees (Cash-Settled)

16.2  Management Board Grant –  

Short-Term Incentive (Cash-Settled)

Description of Share-Based Payments
In December 2020, we approved the BioNTech 2020 Restricted Stock 
Unit  Plan  for  North  America  Employees,  or  the  North  American  Plan.  
Under  the  North  American  Plan,  RSUs  are  offered  to  our  employees. 
These RSUs vest over four years, with 25% vesting one year after the 
service commencement date and the remainder vesting in equal quar-
terly installments thereafter. The first awards under the North American 
Plan were granted in February 2021. The service date for these awards 
is the date as of which the employee became employed by BioNTech US. 
During the years ended December 31, 2023, and 2022, further awards 
were granted under the North American Plan, which included awards 
granted to new-hire employees and ongoing, recurring awards to exist-
ing employees on the approximate anniversary of each employee’s start 
date of employment with BioNTech US. As these RSUs are intended to 
be cash-settled upon vesting, the awards were defined as a cash-settled 
share-based payment arrangement. During the years ended December  
31, 2023, 2022 and 2021, the exercise of RSUs resulted in a cash outflow 
of €10.0 million, €9.4 million and €10.1 million, respectively.

As of December 31, 2023, the liability related to these awards amounted 
to €14.4 million (€13.4 million as of December 31, 2022). 

Management Board’s service agreements also include a short-term in-
centive compensation component, which is an annual performance-relat-
ed bonus for the years of their respective service periods. 

50% of those yearly awards are paid out one year after the achievement 
of the performance targets for the respective bonus year has been deter-
mined, subject to an adjustment relative to the performance of the price 
of  the  American  Depositary  Shares  representing  our  ordinary  shares 
during that year (second installment). The second installments represent 
cash-settled share-based payment arrangements. The fair values of the 
liabilities are recognized over the awards’ vesting periods beginning when 
entering or renewing service agreements, i.e., the service commence-
ment date, until each separate determination date and are remeasured 
until the settlement date. As of December 31, 2023, the liability related to 
these awards amounted to €2.1 million (€2.3 million as of December 31, 
2022). 

3 
 
 
 
 
 
 
 
 
 
 
 
 
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193

The right to receive options generally represents an equity-settled share-
based payment arrangement. The allocation of the number of issued op-
tions in 2020 occurred in February 2020. In May 2021 and May 2022, the 
Management Board received phantom options equivalent to the number 
of options the Management Board members would have been entitled to 
receive for 2021 and 2022, which led to a modification from equity-settled 
to cash-settled share-based payment arrangement and a reclassifica-
tion of €1.1 million and €3.3 million between equity and non-current other 
liabilities as of the respective allocation dates. During 2023, options were 
granted in May 2023. 

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

16.3  Management Board Grant Long-Term Incentive  
(Partly Equity-Settled, Partly Cash-Settled)

Description of Share-Based Payments

Our  Management  Board’s  service  agreements  provide  for  long-term  
incentive compensation (Management Board Grant – LTI) through an  
annual grant of options to acquire BioNTech shares during their respec-
tive service periods. The options granted each year are subject to the 
terms  and  conditions  of  the  respective  authorizations  of  the  Annual  
General Meeting creating our Employee Stock Ownership Plan (ESOP) 
and the applicable option agreements thereunder. 

The options vest annually in equal installments over four years commenc-
ing on the first anniversary of the allocation date and are exercisable four 
years after the allocation date. The vested options can only be exercised 
if each of the following performance criteria has been achieved: (i) at the 
time of exercise, the current price is equal to or greater than the threshold 
amount (that is, the exercise price, provided that such amount increases 
by seven percentage points on each anniversary of the allocation date); 
(ii) at the time of exercise, the current price is at least equal to the target 
price (that is, (a) for the twelve-month period starting on the fourth anni-
versary of the allocation date, $8.5 billion divided by the total number of 
the ordinary shares outstanding immediately following the initial public 
offering  (other  than  ordinary  shares  owned  by  BioNTech),  and  (b)  for 
each twelve-month period starting on the fifth or subsequent anniversary 
of the allocation date, 107% of the target share price applicable for the 
prior twelve-month period); and (iii) the closing price for the fifth trading 
day prior to the start of the relevant exercise window is higher than the 
exercise  price  by  at  least  the  same  percentage  by  which  the  Nasdaq 
Biotechnology Index or a comparable successor index as of such time is 
higher than such index was as of the last trading day before the allocation 
date. Following the expiry of the waiting period, option rights may be ex-
ercised during the exercise windows as set out in the ESOP agreement.  
The option rights can be exercised up to ten years after the allocation 
date. If they have not been exercised by that date, they will be forfeited 
without compensation. 

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Measurement of Fair Values

A Monte-Carlo simulation model has been used to measure the fair values 
at the (estimated) allocation dates of the Management Board Grant. This 
model  incorporates  the  impact  of  the  performance  criteria  regarding 
share price and index development described above. The parameters 
used for measuring the fair values as of the respective (estimated) alloca-
tion dates were as follows:

Weighted average fair value

Weighted average share price

Exercise price (2)

Expected volatility

Expected life (years)

Risk-free interest rate

Allocation date  
February 2020

Allocation date  
May 12, 2021(1)

Allocation date  
May 17, 2021(1)

Allocation date  
May 2022(1)

€10.83

€28.20

€28.32

36.6%

4.8

1.6%

€29.05

€168.44

€167.63

49.7%

4.6

3.9%

€27.64

€179.46

€169.08

49.7%

4.6

3.9%

€38.88

€147.84

€137.65

49.7%

5.8

3.9%

(1)  Classified as cash-settled share-based payment arrangement; all other share-based payment  

(2)  The share options allocated as of February 2020 and May 2023 as well as the phantom share  

arrangements are classified as equity-settled.

options allocated as of May 2021 and 2022 are subject to an effective exercise price cap. 

Weighted average fair value (1)

Weighted average share price (1)

Exercise price (1)

Expected volatility

Expected life (years) (1)

Risk-free interest rate

(1)  Valuation parameter for estimated allocation dates derived from the Monte-Carlo simulation model.

Allocation date  
May 2023

Estimated  
allocation date  
2024

Estimated  
allocation date  
2025

Estimated  
allocation date  
2026

€46.29

€98.93

€105.42

47.2%

5.8

3.7%

€43.67

€95.51

€96.82

47.7%

5.8

3.9%

€39.97

€95.51

€99.74

43.0%

5.8

3.9%

€32.86

€95.51

€105.13

36.8%

5.8

3.9%

3 
 
 
 
 
 
 
 
 
 
 
 
 
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195

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

For the awards with estimated allocation dates, the exercise prices of  
options expected to be allocated have been derived from the Monte-Carlo 
simulation model. Those will be adjusted until the actual allocation has 
occurred and the exercise price has ultimately been determined. 

All options are subject to an effective exercise price cap, which means that 
the exercise price shall be adjusted to ensure that the current price of an 
ADS as of the exercise date does not exceed 800% of the exercise price. 
With respect to the LTI 2020 agreement, the maximum economic benefit 
receivable in respect of any exercised option is capped at $246.24, with 
the effective exercise price being capped at a Euro amount equivalent 
to $30.78. With respect to the phantom share options issued under the 
LTI 2021 and 2022 as well as the options issued under the LTI 2023 pro-
grams, the maximum compensation that the Management Board mem-
bers are entitled to receive under such programs, together with other 
compensation components received by each such board member in the 
respective grant year, shall not exceed €20.0 million for Ugur Sahin as 
Chief Executive Officer (CEO) and €10.0 million for all other Management 
Board members. 

Expected volatility was based on an evaluation of the historical volatilities 
of comparable companies over the historical period commensurate with 
the  expected  option  term.  The  expected  term  was  based  on  general  
option holder behavior for employee options. 

3 
 
 
 
 
 
 
 
 
 
 
 
 
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196

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Reconciliation of Outstanding Share-Options

The (phantom) share options allocated and expected to be allocated to 
our Management Board as of December 31, 2023, are presented in the 
table below. 

(Phantom) share options outstanding

 Thereof allocated and vested but subject to performance and  
waiting requirements

  Thereof allocated and unvested

Weighted average exercise price (€)

(1)  Classified as cash-settled share-based payment arrangement; all other share-based payment  

arrangements are classified as equity-settled.

Allocation date  
February 2020

Allocation date  
May 12, 2021 (1)

Allocation date  
May 17, 2021 (1)

Allocation date  
May 2022 (1)

248,096

186,072

62,024

28.32

45,279

22,640

22,639

167.63

6,463

3,232

3,231

169.08

86,118

21,531

64,587

137.65

Share options outstanding/expected to be allocated

  Thereof allocated and unvested

Weighted average exercise price (€)

(1)  Valuation parameter derived from the Monte-Carlo simulation model.

Allocation date  
May 2023 (1)

Estimated allocation  
date 2024 (1)

Estimated allocation  
date 2025 (1)

Estimated allocation  
date 2026 (1)

130,586

130,586

105.42

164,148

—

96.82

118,312

—

99.74

93,561

—

105.13

For the awards with estimated allocation dates, the numbers of options 
expected to be allocated have been derived from a Monte-Carlo simula-
tion model. Those will be adjusted until the actual allocation has occurred 
and the number of options granted has ultimately been determined. 

As of December 31, 2023, the share options allocated and expected to 
be allocated under our equity-settled share-based payment arrange-
ments had a remaining weighted average expected life of 4.1 years (as of  
December 31, 2022: 4.0 years). 

As  of  December  31,  2023,  the  liability  related  to  the  phantom  option 
awards amounted to €3.6 million (€5.6 million as of December 31, 2022). 

3 
 
 
 
 
 
 
 
 
 
 
 
 
 
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197

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

16.4 Chief Executive Officer Grant (Equity-Settled)

Measurement of Fair Values

A Monte-Carlo simulation model has been used to measure the fair value 
at the grant date of the Chief Executive Officer Grant. This model incor-
porates the impact of the performance criteria regarding share price and 
index development described above in the calculation of the award’s fair 
value at the grant date. The inputs used in the measurement of the fair val-
ue at the grant date of the Chief Executive Officer Grant were as follows:

Weighted average fair value

Weighted average share price

Exercise price

Expected volatility

Expected life (years)

Risk-free interest rate

Grant date  
October 9, 2019

€5.63

€13.60

€13.60

41.4%

5.4

1.5%

Expected volatility was based on an evaluation of the historical volatilities 
of comparable companies over the historical period commensurate with 
the  expected  term.  The  expected  term  was  based  on  general  option  
holder behavior for employee options.

Description of Share-Based Payments

In  September  2019,  we  granted  Ugur  Sahin  an  option  to  purchase 
4,374,963 of our ordinary shares, subject to Sahin’s continuous employ-
ment with us. The options’ exercise price per share is the Euro translation 
of the public offering price from our initial public offering, €13.60 ($15.00), 
which is subject to the effective exercise price cap and the maximum cap 
mechanism. Under the exercise price cap the exercise price shall be ad-
justed to ensure that the current price of an ADS as of the exercise date 
does not exceed 800% of the exercise price. Under the maximum cap 
mechanism the maximum economic benefit receivable in respect of any 
exercised option is capped at $240.00 with the effective exercise price 
being capped at a Euro amount equivalent to $30.00. 

The options vest annually in equal installments after four years commenc-
ing on the first anniversary of the initial public offering and have a waiting 
period of four years after the initial public offering. The vested option 
rights can only be exercised if and to the extent that each of the following 
performance criteria has been achieved: (i) at the time of exercise, the 
current price is equal to or greater than the threshold amount (that is, 
the exercise price, provided that such amount increases by seven per-
centage points on each anniversary of the allocation date); (ii) at the time 
of exercise, the current price is at least equal to the target price (that 
is, (a) for the twelve-month period starting on the fourth anniversary of 
the allocation date, $8.5 billion divided by the total number of the shares 
outstanding immediately following the initial public offering (other than 
shares owned by us), and (b) for each twelve-month period starting on the 
fifth or subsequent anniversary of the allocation date, 107% of the target 
share price applicable for the prior twelve-month period); and (iii) the clos-
ing price for the fifth trading day prior to the start of the relevant exercise 
window is higher than the exercise price by at least the same percentage 
by which the Nasdaq Biotechnology Index or a comparable successor 
index as of such time is higher than such index was as of the last trading 
day before the allocation date. Following the expiry of the waiting period, 
option rights may be exercised during the exercise windows as defined 
by our ESOP. The option rights can be exercised up to ten years after the 
allocation date. If they have not been exercised by that date, they will be 
forfeited without compensation. 

3 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

198

versary date. Following the expiry of the waiting period, option rights may 
be exercised within a period of four weeks from the date of the Annual 
General Meeting or the publication of the annual financial statements, the 
semi-annual report or our most recent quarterly report or interim report 
(exercise windows). The option rights can be exercised up to eight years 
after the allocation date. If they have not been exercised by that date, they 
will be forfeited without compensation. 

By way of a shareholders’ resolution of the general meeting on August 
19, 2019, the authorization to issue such option rights was amended such 
that, in order for the options to be exercisable, the average closing price 
of the Company’s shares or the average closing price of the right or cer-
tificate to be converted into an amount per share on the ten trading days 
immediately preceding the exercise must exceed the strike price by a 
minimum of 28%, with this percentage increasing by seven percentage 
points as of the fifth anniversary of the issue date and as of each subse-
quent anniversary date. Furthermore, in addition to the aforementioned 
requirements, the exercise is only possible if the share price (calculated 
by reference to the price of the ordinary share underlying the ADS) has 
performed  similar  to  or  better  than  the  Nasdaq  Biotechnology  Index.  
The changes made do not affect option rights already issued.

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Reconciliation of Outstanding Share-Options

On  October  9,  2023,  with  the  final  installment  vesting,  all  4,374,963  
options became exercisable under the rules of the ESOP and the ESOP 
agreement. During the year ended December 31, 2023, no options were 
exercised.

As of December 31, 2023, the share options outstanding had a remaining 
weighted average expected life of 1.1 years (as of December 31, 2022:  
2.1 years).

16.5  Employee Stock Ownership Plan  

(Partly Equity-Settled, Partly Cash-Settled)

Description of Share-Based Payments

Based on an authorization of the general meeting on August 18, 2017, we 
established a share option program under which we granted selected 
employees options to receive our shares. The program is designed as an 
Employee Stock Ownership Plan, or ESOP. We offered participants a cer-
tain number of option rights by their explicit acceptance of an option rights 
agreement. The exercise of option rights in accordance with the agree-
ment gives the participants the right to obtain shares against payment 
of the exercise price. With respect to the Management Board members 
serving at the time of allocation, the options are subject to the effective  
exercise price cap and maximum cap mechanisms. Under the exercise 
price cap, the exercise price shall be adjusted to ensure that the current 
price of an ADS as of the exercise date does not exceed 800% of the  
exercise price. Under the maximum cap mechanism, the maximum eco-
nomic benefit receivable in respect of any exercised option, is capped 
at $240, with the effective exercise price being capped at a Euro amount 
equivalent to $30.00. Under the ESOP, the option rights (other than Özlem 
Türeci’s, and Ryan Richardson’s options) fully vest after four years and can 
be exercised if: (i) the waiting period of four years has elapsed; and (ii) at 
the time of exercise, the average closing price of the shares of the Com-
pany or the average closing price of the right or certificate to be converted 
into an amount per share on the previous ten trading days preceding the 
exercise of the option right exceeds the strike price by a minimum of 32%, 
with this percentage increasing by eight percentage points as of the fifth 
anniversary of the respective issue date and as of each subsequent anni-

3 
 
 
 
 
 
 
 
 
 
 
 
 
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199

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Measurement of Fair Values

The fair value of the ESOP has been measured using a binomial model.  
Service  conditions  attached  to  the  arrangement  were  not  taken  into  
account in measuring the fair value.

The share options can only be exercised by the grantee if the price of 
the share is equal or greater to the threshold amount as defined in the 
arrangement. Moreover, the option rights can only be exercised if the IPO 
has occurred. Both conditions have been incorporated into the fair value 
at the grant date.

The inputs used in the measurement of the fair values at the grant date of 
the ESOP were as follows:

Weighted average fair value

Weighted average share price

Exercise price (1)

Expected volatility

Expected life (years)

Risk-free interest rate

Grant date  
November 15, 2018

Grant dates between 
February 21 and  
April 3, 2019

Grant dates between 
April 29 and  
May 31, 2019

Grant date  
December 1, 2019

€7.41

€14.40

€10.14

46.0%

5.8

0.1%

€6.93

€15.72

€15.03

46.0%

6.0

0.1%

€7.04

€16.03

€15.39

46.0%

6.0

0.1%

€9.49

€19.84

€15.82

46.0%

5.5

0.1%

(1)  With respect to the Management Board members appointed as such at the time the options were granted, 

the options are subject to the effective exercise price cap as well as the maximum cap mechanism.

Expected volatility has been based on an evaluation of the historical and 
the implied volatilities of comparable companies over the historical period 
commensurate with the expected term. The expected term has been 
based on general option holder behavior for employee options.

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3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Reconciliation of Outstanding Share-Options (Equity-Settled)

Set out below is an overview of changes to share options outstanding and 
number of ordinary shares underlying these options that occurred during 
the periods indicated:

Number of 
ordinary shares 
underlying 
options

Weighted  
average  
exercise 
price(€) (1)

Share options 
outstanding

As of January 1, 2022

642,007

11,556,124

Modified (2)

Exercised (3)

As of December 31, 2022

As of January 1, 2023

Exercised (3)

As of December 31, 2023

  Thereof vested

  Thereof unvested

(1,040)

(18,720)

(583,383)

(10,500,890)

57,584

57,584

(39,785)

17,799

17,799

—

1,036,514

1,036,514

(716,121)

320,393

320,393

—

10.23

10.14

10.14

11.10

11.10

11.04

11.24

11.24

—

(1)  With respect to the Management Board members appointed as such at the time the options were granted, 

the options are subject to the effective exercise price cap as well as the maximum cap mechanism.

(2)  Rights have been modified to cash-settled righ ts, all other terms remained unchanged.

(3)  The average closing price of an American Depositary Share of BioNTech on Nasdaq weighted over 

the various dates immediately preceding the settlement dates, converted from USD to Euro using the 

exchange rate published by the German Central Bank (Deutsche Bundesbank) on the same days was 

€96.49 and €160.44 for all settlements during the years ended December 31, 2023 and 2022, respectively.

In September 2022, the Supervisory Board determined the ESOP settle-
ment by the delivery of treasury shares (in the form of ADSs) equal to the 
net value of the exercised option rights after deduction of (i) the exercise 
price and (ii) the applicable wage taxes (including solidarity surcharge 
thereon and church tax, if applicable) and social security contributions 
resulting from such exercise. The settlement was applied during the ex-
ercise windows in 2022 and 2023. The applicable wage taxes (including 
solidarity  surcharge  thereon  and  church  tax,  if  applicable)  and  social 

security  contributions  resulting  from  and  withheld  upon  the  exercise 
amounted to €724.0 million and were paid in January 2023 in cash directly  
to the respective authorities. The settlement mechanism decision did 
not change the rights as such, neither did it change the classification as 
equity- settled option rights.

As of December 31, 2023, the share options outstanding under our equity- 
settled share-based payment arrangements had a remaining weighted 
average expected life of 0.8 years (as of December 31, 2022: 1.7 years).

Development of Share-Options (Cash-Settled)

Phantom options which were granted under the ESOP mainly during the 
year ended December 31, 2022 each give the participants the right to re-
ceive a cash payment equal to the difference between an exercise closing 
price (average closing price of an American Depositary Share of BioNTech 
on Nasdaq over the last ten trading days preceding the exercise date) 
and the exercise price. The majority of options have an exercise price of 
€10.14. During the years ended December 31, 2023, and 2022, 52,100 
and 289,168 cash-settled phantom option rights were exercised and re-
sulted in a cash outflow of €4.5 million and €42.2 million, respectively.  
The average closing prices (10-day averages) of an American Deposi-
tary Share of BioNTech on Nasdaq weighted over the various settlement 
dates converted from USD to Euro using the exchange rate published 
by the German Central Bank (Deutsche Bundesbank) on the same days 
was €96.25 and €155.39. As of December 31, 2023, 109,651 cash-settled 
option rights remained outstanding. As of December 31, 2023, the liability 
related to cash-settled share-based payment option rights amounted to 
€8.5 million (€14.5 million as of December 31, 2022), of which €8.3 million 
(€11.2 million as of December 31, 2022) related to rights already vested 
(partly subject to performance and waiting requirements). The liability is 
based on the fair value of the respective rights. The fair value is measured 
using a binomial model consistent with the grant date fair value measure-
ment of the equity-based option rights described above, which is updated 
on every reporting date. 

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

17 PROVISIONS

As of December 31, 2023, our current provisions included €79.7 million 
in other obligations mainly comprising inventor remunerations as well 
as customs and duties (€51.4 million as of December 31, 2022, mainly 
comprising inventor remunerations as well as customs and duties). The 
change of €28.3 million compared to the previous period related mainly 
to additions.

(in millions €)

Contractual disputes

Obligations from onerous CMO contracts

Other

Total

Total current

Total non-current

December 31, 2023

December 31, 2022

118.2

80.2

79.7

278.1

269.3

8.8

88.9

235.5

51.4

375.8

367.2

8.6

As of December 31, 2023, our current provisions included €118.2 million 
in contractual disputes mainly related to purported obligations arising out 
of certain contractual disputes unrelated to the below-mentioned patent 
proceedings (€88.9 million as of December 31, 2022). Acknowledging an 
increase in obligations identified as contractual disputes, the change of 
€29.3 million compared to the previous period related mainly to additions.

As  of  December  31,  2023,  our  current  provisions  included  €80.2   
million (€235.5 million as of December 31, 2022) of obligations for pro-
duction capacities derived from contracts with Contract Manufacturing 
Organizations, or CMOs, that became redundant The effects were driven 
by reducing production capacities as well as further fostering the global  
production network with our collaboration partners during the year ended  
December  31,  2023.  The  related  expenses  were  recognized  in  cost 
of  sales  in  our  consolidated  statements  of  profit  or  loss.  The  change 
of €(155.3) million compared to the previous period related to addition 
(€45.1 million), to release (€126.0 million) and usage (€74.5 million). 

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

in the period in which the amounts are accrued or paid. We will continue 
to evaluate whether, if circumstances were to change in the future, the 
recording of a provision may be needed and whether potential indemnifi-
cation entitlements exist against any such claim. 

Certain pending matters to which we are a party are discussed below.

Alnylam Proceedings

In March 2022, Alnylam Pharmaceuticals, Inc., or Alnylam, filed a lawsuit 
against Pfizer and Pharmacia & Upjohn Co. LLC in the U.S. District Court 
for  the  District  of  Delaware  alleging  that  an  existing  patent  owned  by 
Alnylam, U.S. Patent No. 11,246,933, or the ‘933 Patent, is infringed by the 
cationic lipid used in Comirnaty, and seeking monetary relief, which is not 
specified in their filings. We filed a counterclaim to become party to the 
Alnylam proceeding, and in June 2022, Alnylam added to its claims alle-
gations that we induced infringement of the ‘933 Patent. Additionally, in 
July 2022, Alnylam filed a lawsuit against us, our wholly owned subsidiary, 
BioNTech Manufacturing GmbH, Pfizer and Pharmacia & Upjohn Co. LLC 
in the U.S. District Court for the District of Delaware alleging that we also 
induced infringement of a newly issued patent, U.S. Patent No. 11,382,979, 
or the ‘979 Patent, which is a continuation of the ‘933 Patent. The two 
lawsuits were consolidated on July 28, 2022. In May 2023, Alnylam filed 
a third lawsuit against Pfizer Inc. and Pharmacia & Upjohn Co. LLC in the 
U.S. District Court for the District of Delaware alleging infringement of U.S. 
Patent Nos. 11,633,479; 11,633,480; 11,612,657; and 11,590,229, all of which 
are continuations of the ‘933 Patent. We filed a counterclaim to become 
party to the new proceeding, and in July 2023, Alnylam added to its claims 
allegations that we induced infringement of the four new patents. All of the 
proceedings have been consolidated and are currently pending.

18  CONTINGENCIES AND OTHER  
FINANCIAL COMMITMENTS

Contingencies

Our contingencies include, but are not limited to, intellectual property 
disputes and product liability and other product-related litigation. From 
time to time, in the normal course and conduct of our business, we may 
be involved in discussions with third parties about considering, for exam-
ple, the use and/or remuneration for use of such third party’s intellectual 
property. As of December 31, 2023, none of such intellectual property- 
related considerations that we have been notified of, and for which po-
tential claims could be brought against us or our subsidiaries in the future, 
fulfill the criteria for recording a provision. We are subject to an increasing 
number of product liability claims. Such claims often involve highly com-
plex issues related to medical causation, correctness and completeness 
of product information (Summary of Product Characteristics/package 
leaflet) as well as label warnings and reliance thereon, scientific evidence 
and findings, actual and provable injury, and other matters. These com-
plexities vary from matter to matter. As of December 31, 2023, none of 
these claims fulfill the criteria for recording a provision. Substantially all of 
our contingencies are subject to significant uncertainties and, therefore, 
determining the likelihood of a loss and/or the measurement of any loss 
can be complex. Consequently, we are unable to estimate the range of 
reasonably possible loss. Our assessments, which result from a complex 
series of judgments about future events and uncertainties, are based on 
estimates and assumptions that have been deemed reasonable by man-
agement, but that may prove to be incomplete or inaccurate, and unantici-
pated events and circumstances may occur that might cause us to change 
those estimates and assumptions. We currently do not believe that any of 
these matters will have a material adverse effect on our financial position, 
and will continue to monitor the status of these and other claims that may 
arise. However, we could incur judgments, enter into settlements or revise 
our expectations regarding the outcome of matters, which could have a 
material adverse effect on our results of operations and/or our cash flows 

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Infringement Proceedings – EP’755, DE’123, and DE’130
In  July  2023,  CureVac  SE  filed  a  second  lawsuit  against  us  and  our  
wholly  owned  subsidiaries,  BioNTech  Manufacturing  GmbH  and  
BioNTech  Manufacturing  Marburg  GmbH,  in  the  Düsseldorf  
Regional  Court,  alleging  Comirnaty’s  infringement  of  one  Europe-
an patent, EP4023755B1, or the EP’755 Patent, and two Utility Models 
DE202021004123U1, and DE202021004130U1.

Nullity Proceedings – EP’122
In September 2022, we filed a nullity action in the Federal Patent Court of 
Germany seeking a declaration that the EP’122 Patent is invalid. In April 
2023, the Federal Patent Court of Germany issued a preliminary opinion in 
the EP’122 nullity action in support of the validity of the EP’122 Patent. The 
preliminary opinion did not address any infringement of the EP’122 Patent.  
The preliminary opinion is a preliminary assessment by the court of the 
merits of a claim, and is non-binding. On December 19, 2023, the Federal 
Patent Court held an oral hearing, after which it nullified EP’122. 

Cancellation Proceedings– DE’961, DE‘974, and DE’575
In November 2022, we filed cancellation actions seeking the cancellation 
of the three German Utility Models in the German Patent and Trademark 
Office. On December 27, 2023, the German Patent Office issued a pre-
liminary opinion that DE’974 is likely to be cancelled based on invalidity 
pursuant to para. 1 (2) no. 5 Utility Model Act.

We believe we have strong defenses against the allegations claimed rela-
tive to each of the patents and intend to vigorously defend ourselves in the 
proceedings mentioned above. However, our analysis of Alnylam’s claims 
is ongoing and complex, and we believe the outcome of the suit remains 
substantially uncertain. Taking into account discussions with our external 
lawyers, we do not consider the probability of an outflow of resources 
to be sufficient to recognize a provision at the balance sheet date. In our 
opinion, these matters constitute contingent liabilities as of the balance 
sheet date. However, it is currently impractical for us to estimate with suffi-
cient reliability the respective contingent liabilities.

CureVac Proceedings

Germany
Infringement Proceedings – EP’122, DE’961, DE‘974, DE’575, and EP’668
In  July  2022,  CureVac  AG,  or  CureVac,  filed  a  lawsuit  against  us  and 
our  wholly  owned  subsidiaries,  BioNTech  Manufacturing  GmbH  and  
BioNTech  Manufacturing  Marburg  GmbH,  in  the  Düsseldorf  Regional  
Court,  alleging  Comirnaty’s  infringement  of  one  European  patent,  
EP1857122B1,  or  the  EP’122  Patent,  and  three  Utility  Models 
DE202015009961U1, DE202015009974U1, and DE202021003575U1. 
In August 2022, CureVac added European Patent EP3708668B1, or the 
EP’668 Patent, to its German lawsuit.

On August 15, 2023, the Düsseldorf Regional Court held a hearing on 
infringement with respect to all five IP rights. At the hearing, the Court sus-
pended its infringement ruling with respect to EP’122 until December 28, 
2023. On September 28, 2023, the Court issued orders suspending its 
infringement rulings with respect to the remaining four IP rights (DE’961, 
DE’974, DE’575, and EP’668) pending validity decisions in the DE’961, 
DE’974, and DE’575 cancellation proceedings before the German Patent 
and Trademark Office and in the EP’668 opposition proceedings before 
the Opposition Division of the European Patent Office. In the September 
28th orders, the Court explained that it was suspending its infringement 
rulings  until  validity  decisions  are  reached,  while  contemporaneously 
noting concerns regarding the validity of DE’961, DE’974, DE’575, and 
EP’668. On December 28, 2023, the Düsseldorf Regional Court stayed 
the infringement proceedings as to EP’122 until a final appellate decision 
is rendered as to the validity of EP 122 by the Federal Court of Justice.

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

United States 
In July 2022, we and Pfizer filed a complaint for a declaratory judgment in 
the U.S. District Court for the District of Massachusetts, seeking a judg-
ment of non-infringement by Comirnaty of U.S. Patent Nos. 11,135,312, 
11,149,278 and 11,241,493. In May 2023, the action in the U.S. District Court 
for the District of Massachusetts was transferred to the U.S. District Court 
for the Eastern District of Virginia, where CureVac filed counterclaims 
asserting  infringement  of  six  additional  U.S.  patents,  U.S.  Patent  Nos. 
10,760,070; 11,286,492; 11,345,920; 11,471,525; 11,576,966; and 11,596,686. 
In July 2023, CureVac filed amended counterclaims to assert an additional  
U.S. patent, U.S. Patent No. 11,667,910.

United Kingdom 
In September 2022, we and Pfizer filed a declaration of non-infringement 
and revocation action against the EP’122 Patent and the EP’668 Patent 
in the Business and Property Courts of England and Wales. In October 
2022, CureVac responded by filing a counterclaim alleging infringement 
of the EP’122 and EP’668 patents in the Business And Property Courts of 
England and Wales. On December 18, 2023, we amended our pleadings 
to further allege non-infringement and invalidity against EP’755.

All of the above proceedings are currently pending.

We  believe  we  have  strong  defenses  against  the  allegations  claimed  
relative to each of the patents and utility models and intend to vigorously 
defend ourselves  in  the  proceedings mentioned above. However, our 
analysis of CureVac’s claims is ongoing and complex, and we believe the 
ultimate outcomes remain substantially uncertain. Taking into account 
discussions with our external lawyers, we do not consider the probability 
of an outflow of resources to be sufficient to recognize a provision at the 
balance sheet date. In our opinion, these matters constitute contingent 
liabilities as of the balance sheet date. However, it is currently impracti-
cal for us to estimate with sufficient reliability the respective contingent  
liabilities.

Moderna Proceedings

Germany
Infringement Proceedings – EP’949 and EP’565
In August 2022, Moderna filed a lawsuit against us and Pfizer and our 
wholly owned subsidiaries, BioNTech Manufacturing GmbH, BioNTech 
Europe  GmbH  and  BioNTech  Manufacturing  Marburg  GmbH,  Pfizer  
Manufacturing Belgium NV, Pfizer Ireland Pharmaceuticals and Pfizer Inc. 
in the Düsseldorf Regional Court alleging Comirnaty’s infringement of two 
European Patents, 3590949B1, or the EP’949 Patent, and 3718565B1, 
or the EP’565 Patent. On November 7, 2023, the European Patent Office 
(“EPO”) Opposition Division revoked EP’565 after a one-day oral hearing.  
The Opposition Division issued a preliminary opinion on December 8, 
2023 noting that it believes EP’949 is likely invalid. As a result of these EPO 
proceedings, the Düsseldorf Regional Court postponed its hearing on in-
fringement, originally scheduled for December 12, 2023, to January 21,  
2025.

United Kingdom
In August 2022, Moderna filed a lawsuit asserting Comirnaty’s infringe-
ment of the EP’949 Patent and EP’565 Patent against us and our wholly 
owned subsidiaries, BioNTech Manufacturing GmbH, BioNTech Europe 
GmbH and BioNTech Manufacturing Marburg GmbH, Pfizer Limited, Pfizer  
Manufacturing Belgium NV and Pfizer Inc. in the Business and Property 
Courts of England and Wales. In September 2022, we and Pfizer filed a 
revocation action in the Business and Property Courts of England and 
Wales requesting revocation of the EP’949 Patent and EP’565 Patent. 

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  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

United States
U.S. District Court Litigation 
In August 2022, Moderna filed a lawsuit in the United States District Court 
for the District of Massachusetts against us and our wholly owned sub-
sidiaries  BioNTech  Manufacturing  GmbH  and  BioNTech  US  Inc.  and  
Pfizer Inc. alleging Comirnaty’s infringement of U.S. Patent Nos. 10,898,574, 
10,702,600 and 10,933,127 and seeking monetary relief. 

Belgium
In May 2023, Moderna filed a lawsuit against us, our wholly owned sub-
sidiary BioNTech Manufacturing GmbH, Pfizer Inc. and Pfizer Manufactur-
ing Belgium alleging Comirnaty’s infringement of the EP’949 Patent and 
the EP’565 Patent in the Brussels Dutch-speaking Enterprise Court. 

All of the above proceedings are currently pending.

Inter Partes Review

In August 2023, Pfizer and we filed petitions seeking inter partes review 
of U.S. Patent Nos. 10,702,600 and 10,933,127 before the United States 
Patent Trial and Appeal Board.

Netherlands
In September 2022, Moderna filed a lawsuit against us and our whol-
ly  owned  subsidiary  BioNTech  Manufacturing  GmbH  and  Pfizer  B.V.,  
Pfizer Export B.V., C.P. Pharmaceuticals International C.V. and Pfizer Inc. in 
the District Court of The Hague alleging Comirnaty’s infringement of the  
EP  ‘949  Patent  and  the  EP  ’565  Patent.  The  District  Court  of  the 
Hague held a hearing on October 6, 2023 on infringement and validity 
with  respect  to  the  EP  ’949  Patent.  On  December  6,  2023,  the  Court 
found EP’949 to be invalid. The EP’565 case has been stayed pending  
Moderna’s appeal of the Opposition Division’s revocation of EP’565.

Ireland
In May 2023, Moderna filed a lawsuit against us and our wholly owned 
subsidiary BioNTech Manufacturing GmbH, Pfizer Inc., Pfizer Healthcare  
Ireland,  Pfizer  Ireland  Pharmaceuticals,  and  C.P.  Pharmaceuticals  
International C.V. alleging Comirnaty’s infringement of the EP’949 Patent 
and EP’565 Patent in the High Court of Ireland.  

We believe we have strong defenses against the allegations claimed rel-
ative to each of the patents and intend to vigorously defend ourselves in 
the proceedings mentioned above. However, our analysis of Moderna’s 
claims is ongoing and complex, and we believe the outcome of the suit 
remains substantially uncertain. Taking into account discussions with 
our external lawyers, we do not consider the probability of an outflow of 
resources to be sufficient to recognize a provision at the balance sheet 
date. In our opinion, these matters constitute contingent liabilities as of the 
balance sheet date. However, it is currently impractical for us to estimate 
with sufficient reliability the respective contingent liabilities.

Arbutus and Genevant Proceedings

In  April  2023,  Arbutus  Biopharma  Corp.,  or  Arbutus,  and  Genevant  
Sciences GmbH, or Genevant, filed a lawsuit against Pfizer and us in the 
U.S. District Court for the District of New Jersey alleging that Pfizer and 
we have infringed the following patents owned by Arbutus: U.S. Patent 
Nos. 9,504,651; 8,492,359; 11,141,378; 11,298,320; and 11,318,098, through 
the  use  of  Genevant’s  lipid  nanoparticle  technology  and  methods  for 
producing such lipids in Comirnaty, and seeking monetary relief. This pro-
ceeding is currently pending.

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  CONSOLIDATED STATEMENTS OF 
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  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

We  believe  we  have  strong  defenses  against  the  allegations  claimed  
relative to each of the patents and intend to vigorously defend ourselves 
in the lawsuit mentioned above. However, our analysis of Arbutus and 
Genevant’s claims is ongoing and complex, and we believe the outcome of 
the suit remains substantially uncertain. Taking into account discussions 
with our external lawyers, we do not consider the probability of an outflow 
of resources to be sufficient to recognize a provision at the balance sheet 
date. In our opinion, these matters constitute contingent liabilities as of the 
balance sheet date. However, it is currently impractical for us to estimate 
with sufficient reliability the respective contingent liabilities.

Promosome Proceedings

In  June  2023,  Promosome  LLC  filed  a  lawsuit  against  Pfizer,  us,  and  
BioNTech Manufacturing GmbH in the U.S. District Court for the South-
ern District of California alleging that Pfizer and our Comirnaty vaccine 
has infringed U.S. Patent No. 8,853,179, and seeking monetary relief. On  
October 4, 2023, the parties filed a joint stipulation of dismissal, dismiss-
ing the lawsuit with prejudice. As part of this stipulation of dismissal, Pro-
mosome agreed to a covenant not to assert U.S. Patent No. 8,853,179 
against  Pfizer  and  us  or  any  of  their  products,  including  Comirnaty.  
This matter is considered closed.

Other financial commitments

The other financial commitments were as follows:

(in millions €)

December 31, 2023

December 31, 2022

Commitments under purchase agreements 
for property, plant and equipment

Contractual obligation to acquire  
intangible assets

Total

154.4

1,721.1

1,875.5

105.2

—

105.2

Contractual  obligations  to  acquire  intangible  assets  exist  in  connec-
tion  with  in-licensing  and  research  and  development  collaborations.  
We  have  entered  into  obligations  to  make  milestone  payments  once  
specific targets have been reached. Provided that all of the milestone 
events are achieved, we would be obligated to pay up to €1,721.1 million as of  
December  31,  2023  (nil  as  of  December  31,  2022)  in  connection  with 
the acquisition of intangible assets. The amounts shown represent the 
maximum payments to be made, and it is unlikely that they will all fall due. 
The amounts and the dates of the actual payments may both vary consid-
erably from those stated in the table, since the achievement of the con-
ditions for payment is possible but uncertain. Other financial obligations 
from possible future sales-based milestone and license payments were 
not included in the table above.

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

The expected maturities of payment obligations under purchase agree-
ments for property, plant and equipment and contractual obligations to 
acquire intangible assets are as follows:

Year ended December 31, 2023  

(in Millionen €)

Commitments under purchase agreements for property, plant and equipment

Contractual obligation to acquire intangible assets

Total

Other financial obligations were recognized at nominal value.

Less than 1 year

1 to 5 years

More than 5 years

152.5

249.4

401.9

1.9

954.9

956.8

—

516.8

516.8

Total

154.4

1,721.1

1,875.5

3 
 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

19  OTHER NON-FINANCIAL  

LIABILITIES

(in millions €)

Liabilities to employees 

Liabilities from share-based payment 
arrangements

Liabilities from wage taxes and  
social securities expenses

Other

Total

Total current

Total non-current

December 31, 2023

December 31, 2022

73.3

29.0

15.1

20.8

138.2

125.1

13.1

50.6

36.2

761.8

29.2

877.8

860.8

17.0

3 
 
 
 
 
 
 
 
 
 
 
 
 
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20.2  Amounts Recognized in the Consolidated Statements 

of Profit or Loss

Depreciation Charge of Right-of-Use Assets

(in millions €)

Buildings

Production facilities 

Other operating equipment

Total depreciation charge

Interest on lease liabilities

Expense related to short-term 
leases and leases of low-value 
assets

Total amounts recognized  
in profit or loss

Years ended December 31,

2023

40.7

3.0

1.5

45.2

5.7

58.9

109.8

2022

35.2

23.1

0.5

58.8

5.1

27.1

91.0

2021

14.7

14.0

0.3

29.0

2.9

9.5

41.4

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

20 LEASES

20.1  Amounts Recognized in the Consolidated Statements 

of Financial Position

Right-of-Use Assets

The following amounts are presented as right-of-use assets within the 
consolidated statements of financial position as of the dates indicated: 

(in millions €)

Buildings

Production facilities 

Other operating equipment

Total

December 31, 2023

December 31, 2022

209.8

—

4.6

214.4

206.5

3.0

2.4

211.9

Additions to the right-of-use assets during the year ended December 31, 
2023, were €66.4 million (during the year ended December 31, 2022: 
€118.3 million).

Lease Liability

The following amounts are included in lease liabilities, loans and borrow-
ings as of the dates indicated: 

(in millions €)

Current

Non-current

Total

December 31, 2023

December 31, 2022

28.1

188.6

216.7

36.0

174.1

210.1

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

20.3  Amounts Recognized in the Consolidated Statements 

of Cash Flows

During the year ended December 31, 2023, the total cash outflow for leases  
amounted to €46.0 million (during the year ended December 31, 2022: 
€46.2 million; during the year ended December 31, 2021: €17.0 million).

20.4 Extension Options

The Group has several lease contracts that include extension options. 
These  options  are  negotiated  by  management  to  provide  flexibility  in 
managing the leased asset portfolio and align with the Group’s business 
needs. Management exercises judgment in determining whether these 
extension options  are  reasonably  certain  to  be  exercised.  The undis-
counted potential future lease payments, which relate to periods after 
the exercise date of renewal options and are not included in lease liabili-
ties, amount to up to €157.2 million as of December 31, 2023, considering 
terms up until 2049 (as of December 31, 2022: €163.1 million considering 
terms up until 2049).

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

21 RELATED PARTY DISCLOSURES

Key Management Personnel Compensation

21.1 Parent and Ultimate Controlling Party

ATHOS KG, Holzkirchen, Germany is the sole shareholder of AT Impf 
GmbH, Munich, Germany and beneficial owner of our ordinary shares. 
ATHOS KG via AT Impf GmbH has de facto control over BioNTech based 
on its substantial shareholding, which practically enables it to exercise 
the majority of voting rights to pass resolutions at our Annual General 
Meeting, or AGM. 

21.2 Transactions with Key Management Personnel

In May 2023, at the Annual General Meeting, our shareholders reappoint-
ed Ulrich Wandschneider and Michael Motschmann as members of the 
Supervisory Board. In addition, Nicola Blackwood was appointed to our 
Supervisory Board. She succeeded Christoph Huber, who left the Super-
visory Board after reaching the applicable retirement age limit.

Our key management personnel has been defined as the members of the 
Management Board and the Supervisory Board. Key management per-
sonnel compensation is comprised of the following:

(in millions €)

Management Board

  Fixed compensation

 Short-term incentive –  
first installment

 Short-term incentive –  
second installment (1)

 Other variable compensation (2)

 Share-based payments  
(incl. long-term incentive) (3)

Supervisory Board

Total compensation paid to  
key management personnel

Years ended December 31,

2023

8.3

3.9

0.7

1.0

0.8

1.9

0.6

8.9

2022

15.0

2.9

0.6

0.7

0.1

10.7

0.5

15.5

2021

20.4

2.2

0.6

1.2

—

16.4

0.4

20.8

(1)  The fair value of the second installment of the short-term incentive compensation which has been  

classified as a cash-settled share-based payment arrangement was determined pursuant to the  

regulations of IFRS 2 “Share-based Payments.” This table shows the pro-rata share of personnel  

expenses for the respective financial year that are recognized over the award’s vesting period beginning  

as of the service commencement date (date when entering or renewing service agreements) until  

each separate determination date and are remeasured until settlement date. 

(2)  Includes a one-time signing and retention cash payment agreed when renewing the service agreement 

agreed with Sean Marett.

(3)  The fair value of the share-based payments was determined pursuant to the regulations of IFRS 2  

“Stock-based Payments”. This table shows the pro-rata share of personnel expenses resulting from 

stock-based compensation for the respective financial year. During the years ended December 31, 2023, 

2022, and 2021, the amounts included expenses derived from a one-time signing bonus granted to Jens 

Holstein as of his appointment to the Management Board in the form of 4,246 phantom shares. 

3 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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212

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

Management Board members participated in our ESOP program (see 
Note 16). Out of the 5,152,410 option rights granted to our Management 
Board under the ESOP 2018 program 4,921,630 options were exercised 
during the year ended December 31, 2022. The remaining 230,780 option 
rights were exercised by Sean Marett in May 2023. As of December 31, 
2023, no further options issued to our Management Board members are 
outstanding. 

The outstanding balances of transactions with ATHOS KG or entities con-
trolled by them were as follows as of the periods indicated:

(in millions €)

ATHOS KG

Total

December 31, 2023

December 31, 2022

0.4

0.4

—

—

21.3 Related Party Transactions

None of the balances are secured and no bad debt expense has been 
recognized in respect of amounts owed by related parties. 

The total amount of transactions with ATHOS KG or entities controlled by 
it was as follows for the periods indicated:

(in millions €)

2023

2022

2021

Years ended December 31,

Purchases of various goods and 
services from entities controlled 
by ATHOS KG

Purchases of property and other 
assets from entities controlled  
by ATHOS KG

Total

0.3

—

0.3

0.3

62.5

62.8

0.9

—

0.9

On  December  22,  2022,  we  entered  into  a  purchase  agreement  with 
Santo Service GmbH, pursuant to which we acquired the real estate prop-
erty An der Goldgrube 12 and the existing laboratory and office building 
including any movable assets for a total consideration of €62.5 million. 
The purchase price was paid during the year ended December 31, 2022. 
Santo Service GmbH is wholly owned by AT Impf GmbH, that is controlled 
by ATHOS KG.

3 
 
 
 
 
 
 
 
 
 
 
 
 
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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

22 NUMBERS OF EMPLOYEES

The average number of employees is: 

The average number of employees as of the reporting date is: 

Years ended December 31,

Years ended December 31,

Quarterly average number  
of employees by function

Clinical Research & Development

Scientific Research & Development 

Operations

Quality

Support Functions

Commercial & Business  
Development 

Total

2023

434

1,871

1,469

470

1,217

179

5,640

2022

243

1,302

1,240

383

828

108

4,104

2021

137

875

863

322

431

66

Number of employees by function 
as of the reporting date

Clinical Research & Development

Scientific Research & Development

Operations

Quality

Support Functions

Commercial & Business  
Development

2,694

Total

2023

592

2,080

1,562

474

1,390

194

6,292

2022

274

1,512

1,365

413

983

145

4,692

2021

153

1,026

1,036

301

539

83

3,138

3 
 
 
 
 
 
 
 
 
 
 
 
 
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214

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

23 FEES FOR AUDITORS

The  following  fees  were  recognized  for  the  services  provided  by  
EY GmbH & Co. KG Wirtschaftsprüfungsgesellschaft for the fiscal years 
ended December 31, 2023 and December 31, 2022: 

(in millions €)

Audit fees

Audit-related fees

Tax fees

All other fees

Total fees for professional audit  
services and other services 

Years ended December 31,

2023

2022

3.2

0.3

0.1

—

3.6

2.9

0.4

0.2

0.2

3.7

3 
 
 
 
 
 
 
 
 
 
 
 
 
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215

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

24 CORPORATE GOVERNANCE

The  declaration  of  conformity  pursuant  to  Section  161  para.  1  of  the  
German Stock Corporation Act (Aktiengesetz) is issued in accordance 
with the Corporate Governance Code in connection with the corporate 
governance declaration pursuant to Section 315d in conjunction with 
Section 289f HGB and can be found in the combined management report 
of BioNTech SE. 

3 
 
 
 
 
 
 
 
 
 
 
 
 
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216

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

  CONSOLIDATED STATEMENTS OF 
  PROFIT OR LOSS 

  CONSOLIDATED STATEMENTS OF 
  COMPREHENSIVE INCOME

  CONSOLIDATED STATEMENTS OF 
  FINANCIAL POSITION

  CONSOLIDATED STATEMENTS OF
  CHANGES IN STOCKHOLDERS’ EQUITY

  CONSOLIDATED STATEMENTS OF 
  CASH FLOWS

  NOTES TO THE CONSOLIDATED 
  FINANCIAL STATEMENT 

4  COMPENSATION REPORT 

5  FURTHER INFORMATION

25  EVENTS AFTER THE REPORTING 

PERIOD

The  Supervisory  Board  has  appointed  Annemarie  Hanekamp  to  the  
Management Board as Chief Commercial Officer (CCO), effective as of 
July 1, 2024. She will take over the role from Sean Marett, who will retire as 
planned from the Management Board as of June 30, 2024. 

Mainz, March 18, 2024

BioNTech SE

On  February  8,  2024,  we  and  Autolus  Therapeutics  plc,  or  Autolus,  a 
clinical-stage biopharmaceutical company developing next-generation 
programmed T cell therapies, announced a strategic collaboration aimed 
at advancing both companies' autologous CAR-T programs towards com-
mercialization. We have entered into a license and option agreement and a 
securities purchase agreement under which we purchased $200.0 million  
of  Autolus'  American  Deposit  Shares  in  a  private  placement  closed 
on February 13, 2024 resulting in a stake in Autolus ordinary shares of 
12.5%. Under the terms of the license and option agreement, we made 
a  $50.0  million  upfront  payment  in  exchange  for  the  right  to  receive  
royalties on net sales of Autolus' lead asset obe-cel, co-commercializa-
tion options for Autolus' AUTO1/22 and AUTO6NG programs as well as 
an exclusive license and exclusive options to certain technologies owned 
by Autolus.

Prof. Ugur Sahin, M.D. 
Chief Executive Officer 

Jens Holstein
Chief Financial Officer

Sean Marett 
Chief Business Officer and  
Chief Commercial Officer

Sierk Poetting, Ph.D.
Chief Operating Officer

Ryan Richardson 
Chief Strategy Officer 

James Ryan, Ph.D.
Chief Legal Officer

Prof. Özlem Türeci, M.D.
Chief Medical Officer

3 
 
 
 
 
 
 
 
 
 
 
 
 
Antibody-drug conjugates (ADCs) are protein molecules 
that are designed to carry chemotherapy. As antibodies 
specifically bind their target, they aim to deliver chemo-
therapy only to cancer cells, sparring healthy ones.

217

COMPENSATION 

REPORT 2023 4

BioNTech | Annual Report 2023BioNTech | Annual Report 2023

218

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION 
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

A. COMPENSATION REPORT

The Compensation Report describes the structure and individualized 
amount  of  the  compensation  components  of  the  Management  Board 
and Supervisory Board of BioNTech SE, hereinafter also referred to as 
“BioNTech”, the “Group”, “we” or “us”, as well as the compensation system 
applied for the year ended December 31, 2023.

The Compensation Report is aligned with the requirements of Sec. 162 
German Stock Corporation Act (Aktiengesetz, “AktG”) and the recom-
mendations of the German Corporate Governance Code, as amended on 
April 28, 2022. The disclosures in our Compensation Report are explicitly 
not expense-related and do not follow the IFRS regulations as published 
in our consolidated financial statements or the German Commercial Code 
(HGB) regulations as published in the statutory financial statements of 
BioNTech.

Our Management Board and Supervisory Board have jointly agreed to en-
gage our external auditor to perform a formal audit of the Compensation 
Report. 

We prepare and publish this Compensation Report in Euros and round 
numbers to thousands or millions of Euros respectively. Accordingly, nu-
merical figures shown as totals in some tables may not be exact arithmetic 
aggregations of the figures that preceded them, and figures presented in 
the explanatory notes may not precisely add up to the rounded arithmetic 
aggregations. 

The compensation system of the Management Board and the compen-
sation system of the Supervisory Board approved by the Annual General 
Meeting on June 22, 2021 is published on our website at www.biontech.de 
(https://investors.biontech.de/corporate-governance/overview).

4 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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219

who  left  the  Supervisory  Board  after  reaching  the  applicable  retire-
ment age limit.  Ulrich Wandschneider’s, Nicola Blackwood’s and Michael 
Motschmann’s current appointment to our Supervisory Board will end 
at the AGM in 2027. The compensation system for Supervisory Board 
members for 2023 was retained from 2022. As of October 1, 2023, our 
Supervisory Board established a Product Committee. The Product Com-
mittee advises and makes recommendations to the Supervisory Board 
with respect to our strategy and investment in research and development 
programs and product launch preparations including commercialization. 

The elements of the compensation system and the actual compensation 
according to Sec. 87a AktG are set out below.

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

B.  REVIEW OF THE YEAR ENDED 

DECEMBER 31, 2023

On  May  3,  2023,  our  Supervisory  Board  expanded  our  Management 
Board by appointing James Ryan as Chief Legal Officer (CLO), effective 
as of September 1, 2023. As CLO, James Ryan heads up our legal depart-
ment and is responsible for developing and leading the Company’s corpo-
rate legal strategy to promote and protect BioNTech’s global operations. 
His current appointment to our Management Board will end on August 30, 
2027. Overall, the service agreements with current Management Board 
members encompass terms with end dates that fall between Decem-
ber 31, 2024 and August 31, 2027. The Management Board’s compensa-
tion system is applied whenever service agreements with members of our 
Management Board are entered into, amended or extended.

During the year ended December 31, 2023, the term of office of the Su-
pervisory Board members Ulrich Wandschneider, Christoph Huber, and 
Michael Motschmann, who were elected by the shareholders at the An-
nual General Meeting (AGM) on September 17, 2018, ended at the close 
of the Annual General Meeting on May 25, 2023. As part of the 2023 
AGM, Ulrich Wandschneider and Michael Motschmann were re-elect-
ed as Supervisory Board members. In addition, Nicola Blackwood was 
appointed to our Supervisory Board. She succeeded Christoph Huber, 

219

4 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

220

All members of the Supervisory Board are reimbursed for their expenses. 

The compensation of our Supervisory Board for the years ended Decem-
ber 31, 2023, and 2022 was paid out during December 2023 and Decem-
ber 2022. The fixed compensation and the compensation for committee 
activities of our Supervisory Board members is considered owed and 
granted in the respective financial year in which the underlying services 
were performed.

C.  COMPENSATION OF  

SUPERVISORY BOARD MEMBER

The compensation system of our Supervisory Board as included in our 
Articles of Association is structured as 100% fixed compensation. The 
compensation  system  for  Supervisory  Board  members  for  2023  was 
retained from 2022.

Pursuant to Sec. 113 para. 3 AktG, as amended by the Act Implementing 
the Second Shareholder Rights Directive, the Annual General Meeting 
of a listed company must pass a resolution on the compensation of the 
members of the Supervisory Board at least every four years.

The members of the Supervisory Board receive an annual compensation 
of €70,000, the Chair €210,000 and the Vice Chair €105,000. The Chair 
of the Audit Committee receives an additional annual compensation of 
€30,000. The respective Chair of another committee receives an addi-
tional annual compensation of €15,000. An ordinary committee member 
receives an additional annual remuneration of €5,000 per committee. 

Members of the Supervisory Board who are only members of the Super-
visory Board or committees, or who chair or vice-chair the Supervisory 
Board or the Audit Committee or another committee, for part of the finan-
cial year receive the respective compensation on a pro-rata basis. Hence, 
the compensation of the Supervisory Board members who either left or 
joined in 2023, namely Christoph Huber and Nicola Blackwood, was paid 
on a pro-rata basis with respect to their departure or appointment at our 
AGM on May 25, 2023. In addition, compensation was paid to the mem-
bers of the Product Committee with effect from the date of its establish-
ment as of October 1, 2023.

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

220

44 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

221

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

The compensation granted and owed to our Supervisory Board members 
during the years ended December 31, 2023, and 2022 are presented in 
the following table: 

in thousands €

Base Compensation

2023

2022

Committee Compensation

2023

2022

Total

2023

2022

Helmut Jeggle 
Chair  

Ulrich  
Wandschneider, 
Ph.D. 
Vice Chair

210

210

16

15

226

225

105

105

9

35

114

140

Baroness Nicola  
Blackwood(1)

Prof. Christoph  
Huber, M.D.(2)

Prof. Anja  
Morawietz, Ph.D.

Michael 
Motschmann

Prof. Rudolf  
Staudigl, Ph.D.

42

—

4

—

46

—

28

70

2

10

30

80

70

35

35

—

105

35

70

70

10

25

80

95

70

35

20

—

90

35

(1)  Nicola Blackwood was appointed to the Supervisory Board by the Annual General Meeting on May 25, 2023.

(2)  Christoph Huber served as a member of our Supervisory Board from 2008 and left the Supervisory Board 

on May 25, 2023 after reaching the retirement age limit.

If the reimbursement of expenses or the compensation is subject to val-
ue-added tax, the value-added tax shall be paid in addition. 

The current appointments of our Supervisory Board will end with the 
Annual General Meeting during the respective year set forth below: 

The Supervisory Board members are included in our D&O liability insur-
ance and are co-insured at our expense.

  Helmut Jeggle: 2026

  Ulrich Wandschneider: 2027

  Nicola Blackwood: 2027

  Anja Morawietz: 2026

  Michael Motschmann: 2027

  Rudolf Staudigl: 2026

221

44 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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222

1.3 Involvement of the Annual General Meeting

Pursuant to Sec. 120a para. 1 AktG, the Annual General Meeting (AGM) 
of a listed company must approve the compensation system of the Man-
agement Board presented by the Supervisory Board at least every four 
years and in addition whenever there is a significant change to such sys-
tem. Taking the requirements of Sec. 87a para. 1 AktG into account, the 
Supervisory Board adopted a compensation system for the members of 
the Management Board on May 7, 2021. The compensation system for 
members of the Management Board was approved by the AGM on June 
22, 2021 with a majority of 99.38% of the votes cast and is implement-
ed whenever new service agreements are entered into, existing service 
agreements  are  extended  or  specific  compensation  components  are 
initiated. 

The Supervisory Board expects to submit modifications to the current 
compensation system for the Management Board and to the compensa-
tion for the Supervisory Board to our 2024 AGM for approval. 

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

D.  COMPENSATION OF  

MANAGEMENT BOARD MEMBERS

1 Compensation System

1.1 Compensation System Philosophy

The compensation structure of the Company’s Management Board is 
designed to promote corporate governance and is oriented towards the 
Company’s sustainability and long-term development. Compensation is 
also linked to ethical, ecological and social criteria, reflecting our overall 
strategy and culture. The compensation system therefore sets incentives 
for the sustainable, long-term positive development of the Company as 
a whole and for the long-term commitment of the Management Board 
members. The compensation system is designed to be clear and com-
prehensible. It is aligned with the requirements of the AktG and the rec-
ommendations of the German Corporate Governance Code as amended 
on April 28, 2022 and ensures that the Company’s Supervisory Board can 
react to organizational changes and flexibly take into account changing 
market conditions. 

1.2  Responsibility for Determining the Compensation of the  

Management Board

The Supervisory Board is responsible for determining the structure of the 
compensation system, including targets and caps and the specific com-
pensation of individual Management Board members. The Supervisory 
Board determines the compensation of the Management Board compet-
itively and in line with the market in order to continue to attract and retain 
outstanding individuals.

When determining the specific compensation, the Supervisory Board 
ensures that the compensation of the Management Board is appropriate 
and in line with market customary standards. 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

2  Compensation Components, Target Total Compensation 

and further Provisions

The following table gives an overview of the key provisions of the com-
pensation system, including compensation components and target total 
compensation as approved by the AGM on June 22, 2021. 

Basis of Assessment/Parameters

Strategic Reference

Non-Performance related 
Compensation

Fixed compensation

Fringe benefits

Performance-related 
Compensation

Short-term performance-related 
variable compensation (short-term 
incentive, STI)

Long-term performance-related 
variable compensation (long-term 
incentive, LTI)

Fixed contractually agreed compensation paid in twelve equal monthly 
installments.

Mainly allowances for health and long-term care insurance and 
supplementary insurance, conclusion of D&O insurance with  
deductible in accordance with Sec. 93 para. 2 sentence 3 AktG, 
non-cash benefits from bicycles and travel allowances.

  Target bonus

  Limit on payout amount: up to a maximum of 60% of the amount of fixed 
compensation;

  Performance criteria: Company targets and ESG targets;

  Of the STI, 50% is payable in cash in the month following approval of the 
consolidated financial statements;

  Of the STI, 50% is payable in cash one year after the end of the financial 
year to which the STI relates and subject to an adjustment in relation to 
the share price development one year following the date, when the STI 
achievement is determined. 

  Stock Option Program and/or Restricted Stock Unit Program (RSUP);

  Performance targets: Relative share price development and absolute 
share price development;

  Waiting period: Four years after allocation of the stock options or alloca-
tion of the remaining restricted stock units.

The compensation of the Management Board is based on customary 
market standard. It is also in line with their duties and performance, as well 
as the situation and success of the Group. 

Incentivizes strong annual (non-financial and financial) performance as 
the foundation of the Group’s long-term strategy and sustainable value 
creation with achieving strategic sustainability targets.

The regular LTI is intended to promote the Management Board’s long-term 
commitment to the Group and its sustainable growth. Therefore, the 
performance targets of the LTI are linked to the Group’s long-term share 
price development. 

Continued on next page

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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224

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

Other Compensation Rules

Target total compensation

Basis of Assessment/Parameters

Strategic Reference

  For each Management Board member for the upcoming financial year  
the Supervisory Board sets Target Total Compensation corresponding to 
the sum of fixed compensation (~40%), target STI (~20%) and target LTI 
(~40%, each as percentage of the Target Total Compensation). Relative to 
the Target Total Compensation the individual compensation components 
shall reflect the following percentage ranges.

Sets targets to the compensation of the Management Board to ensure 
a well-weighted combination between fixed and variable compensation 
components. 

  Chief Executive Officer

–  Fixed compensation: 25-35% 
–  Variable compensation: 65-75% 
–  Target STI: 12-18% 
–  Target LTI: 50-60%

  Other Management Board members

–  Fixed compensation: 35-45% 
–  Variable compensation: 55-65% 
–  Target STI: 17-23% 
–  Target LTI: 30-40%

Maximum compensation

Maximum compensation for the financial year in accordance with  
Sec. 87a para. 1 sentence 2 no. 1 AktG:

Caps the compensation of Management Board members to avoid 
uncontrollably high payouts and thus disproportionate costs and risks  
for the Group.

  Chief Executive Officer (CEO): €20 million

  Other Management Board members: €10 million

Maximum compensation can only be achieved if the value of the stock 
options granted under the LTI at the time of exercise of the stock options is 
at least eight times the exercise price. 

Further provisions

  Supervisory Board mandates within the BioNTech group: fully 
compensated for with the compensation as a member of the Management 
Board.

Further provisions also function as a cap in case of different mandates 
within the BioNTech Group to avoid uncontrollably payouts and risks for 
the Group. 

  Supervisory Board mandates outside the BioNTech group: Supervisory 
Board has to approve and decides within the scope of the approval 
whether and to what extent compensation is to be offset against the 
compensation of the Management Board member. 

Continued on next page

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225

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

Basis of Assessment/Parameters

Strategic Reference

Claw-back and malus rules

Severance payment cap

  Service contracts of Management Board members to be newly 
concluded or extended and the terms and conditions of the Stock Option 
Plans and the RSUPs will contain malus and claw-back provisions entitling 
the Company to withhold or reclaim variable compensation components 
in whole or in part in the event of a breach by the Management Board 
member concerned of internal company policies or statutory obligations. 

  Service contracts of Management Board members to be newly 
concluded or extended and the terms and conditions of the Stock 
Option Plan will in future contain a provision obliging Management Board 
members to repay variable compensation already paid out if it transpires 
after payment that the basis for calculating the amount paid out was 
incorrect.

In the event of premature termination, Management Board members 
are granted a severance payment in the amount of the compensation 
expected to be owed by the Company for the remaining term of the 
employment contract, up to a maximum of two years’ compensation.

Ensures sustainable corporate development and ensures avoiding taking 
inappropriate risks.

Caps the compensation of Management Board members in the case of 
premature termination to avoid uncontrollably high payouts and risks for 
the Group.

Continued on next page

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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226

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

of the Management Board are retained and to be able to attract new ap-
pointments to the Management Board, which are in the Company’s long-
term interest. The analysis showed that our compensation system, which 
includes targets and caps, is in line with market standards and complies 
with the German Corporate Governance Code. The Supervisory Board 
will continue to examine the compensation system on a regular basis and 
critically review the need for adjustments in light of sustained internal 
and external developments. In connection with new Nasdaq listing rules 
and U.S. securities regulations, the Supervisory Board expects to submit 
modifications to the current compensation system for the Management 
Board to our 2024 AGM for approval in the event of a future accounting 
restatement. Due to the changes in BioNTech’s operational and financial 
situation since the existing compensation system was adopted in 2021, 
the Compensation, Nominating and Corporate Governance Committee 
has  proposed  a  modification  to  the  compensation  system  during  the 
course of the year ended December 31, 2023, which is currently being 
discussed with the Supervisory Board and it is expected to be proposed 
for approval at the 2024 AGM. The main changes will affect the LTI for the 
Management Board, whereby Performance Share Units (PSUs) will be im-
plemented and the performance hurdles for stock options will also be in-
creased. Furthermore, the pay out structure of the STI will be modified and 
the Company plans to implement a Share Ownership Guideline, which will 
require Management Board members to hold a certain value of BioNTech 
shares or American Depositary Shares (ADSs).

3 Terms of the Current Service Agreements

The  following  sets  forth  the  termination  dates  of  the  current  service 
agreements of our Management Board: 

  Prof. Ugur Sahin, M.D.: December 31, 2026

  Jens Holstein: June 30, 2025

  Sean Marett: December 31, 2024

  Sierk Poetting, Ph.D.: November 30, 2026

  Ryan Richardson: December 31, 2026

  James Ryan, Ph.D.: August 31, 2027

  Prof. Özlem Türeci, M.D.: May 31, 2025

4  Review of the Appropriateness of Management Board 
Compensation for the year ended December 31, 2023

Our current compensation system was derived from a thorough review 
performed by our Supervisory Board, which considered the major trans-
formational changes we underwent in the past, and was approved as of 
June 22, 2021. The service agreements with our Management Board, 
which were extended or concluded during the years ended December 31, 
2021, 2022 and 2023 until the respective dates outlined in section 3, have 
been designed to comply with the compensation system.

Consistent with previous years, in the year ended December 31, 2023, 
we conducted a review of the compensation system to ensure appro-
priateness  and  to  re-assess  current  compensation.  The  assessment 
took into account BioNTech’s market position. We engaged an external 
independent compensation consultant to assess the compensation level 
and structure of our compensation system to ensure that the members 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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227

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

5 Compensation during the year ended December 31, 2023

5.1 Target Total and Maximum Compensation

The Management Board’s target total compensation (TTC) for the years 
ended December 31, 2023, and 2022 is presented below. The following 
table discloses the compensation instruments and demonstrates their 
compliance with the defined target percentage ranges. 

Prof. Ugur Sahin, M.D.

Years ended December 31,

Jens Holstein(1)

Years ended December 31,

2023

2022

2023

2022

in thousand €

in % of TTC

in thousand €

in % of TTC

in thousand €

in % of TTC

in thousand €

in % of TTC

Non-performance related 
compensation

Fixed compensation

Fringe benefits

Performance-related  
compensation

Short-term incentive  

Management Board Grant – LTI

Target Total Compensation (TTC)

700

6

350

1,150

2,206

32

16

52

100

360

6

180

750

1,296

28

14

58

100

550

5

300

550

1,405

39

21

39

100

550

7

300

550

1,407

39

21

39

100

(1)  Jens Holstein’s compensation overview excludes a one-time special payment during the year ended 2023. For further information, see section 5.4.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

Sean Marett(1)

Years ended December 31,

Sierk Poetting, Ph.D.

Years ended December 31,

2023

2022

2023

2022

in thousand €

in % of TTC

in thousand €

in % of TTC

in thousand €

in % of TTC

in thousand €

in % of TTC

Non-performance related 
compensation

Fixed compensation

Fringe benefits

Performance-related  
compensation

Short-term incentive  

Management Board Grant – LTI

Target Total Compensation (TTC)

550

12

300

550

1,412

39

1

21

39

100

513

8

300

550

1,371

37

1

22

40

100

550

5

300

550

1,405

39

21

39

100

550

4

300

550

1,404

39

21

39

100

(1)  Sean Marett’s compensation overview excludes the one-time signing and retention cash payment granted to him at the time of the extension of his service agreement during the year ended 2022. 

Ryan Richardson

Years ended December 31,

James Ryan, Ph.D.(1)

Years ended December 31,

2023

2022

2023

2022

in thousand €

in % of TTC

in thousand €

in % of TTC

in thousand €

in % of TTC

in thousand €

in % of TTC

Non-performance related 
compensation

Fixed compensation

Fringe benefits

Performance-related  
compensation

Short-term incentive  

Management Board Grant – LTI

Target Total Compensation (TTC)

550

26

300

550

1,426

39

2

21

39

100

340

27

170

280

817

42

3

21

34

100

183

-

100

-

283

65

35

100

—

—

—

—

—

—

—

—

—

—

(1)  James Ryan was appointed to the Management Board as Chief Legal Officer (CLO) as of September 1, 2023. His compensation overview excludes the one-time signing bonus granted to him at the time of such appointment. 

For further information, see section 5.3.

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

Non-performance related  
compensation

Fixed compensation

Fringe benefits

Performance-related  
compensation

Short-term incentive  

Management Board Grant – LTI

Target Total Compensation (TTC)

Prof. Özlem Türeci, M.D.

Years ended December 31,

2023

2022

in thousand €

in % of TTC

in thousand €

in % of TTC

550

—

300

550

1,400

39

21

39

100

518

—

300

550

1,368

38

22

40

100

Starting with the phantom share options issued in May 2021 (see section 
5.5), the agreements are subject to a maximum limit on the total compen-
sation that the member is entitled to receive in the grant year, taking into 
account all other compensation received by such member during the 
applicable year. These amounts are €20.0 million for our Chief Executive 
Officer (CEO), and €10.0 million for all other members. For the purposes 
of this limitation, compensation components are attributed to the financial 
year they are granted, irrespective of when they are ultimately paid out. 

5.2 Fixed Compensation and Fringe Benefits

Fixed compensation is primarily paid out as a salary in twelve monthly 
installments. Other components of fixed compensation include fringe 
benefits, such as allowances for health and long-term care insurance and 
supplementary insurance, non-cash benefits for bicycles, and travel al-
lowances. The Management Board also benefits from our D&O insurance 
policy. Our D&O insurance expenses are not considered compensation, 
as they are incurred in the Company’s own interests to cover risks for our 
Management Board and Supervisory Board, and senior executives and 
managing directors of BioNTech group entities. 

Effective January 1, 2023, Ugur Sahin’s annual fixed compensation was 
increased to €700,000 from €360,000 as part of an annual compensa-
tion review to ensure competitive compensation comparable to that of 
companies in a comparable sector and relevant peer group. Jens Hol-
stein’s effective annual fixed compensation was €550,000 during each 
of the years ended December 31, 2023 and 2022. Effective April 1, 2022, 
Sean Marett’s annual fixed compensation was increased from €400,000 
to €550,000. Hence, during the years ended December 31, 2023 and 
2022, his effective annual fixed compensation amounted to €550,000 
and €512,500, respectively. Sierk Poetting’s effective annual fixed com-
pensation amounted to €550,000, respectively, during the years end-
ed December 31, 2023 and 2022. Effective as of his appointment to the 
Management Board as of September 1, 2023, James Ryan’s annual fixed 
compensation was €550,000. His compensation is partly paid in the U.K. 
(in GBP) by the Company's subsidiary, BioNTech UK Limited, and part-
ly in Germany (in Euro). During the year ended December 31, 2023, his 
effective annual fixed compensation as a Management Board member 
amounted to €183,333. Ryan Richardson’s annual fixed compensation 
was increased from €340,000 to €550,000 leading to the respective 
effective annual fixed compensation during the years ended December 31, 

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1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

target achievement of 90%, the annual bonus amounts for Ugur Sahin, 
Jens Holstein, Sean Marett, Sierk Poetting, Ryan Richardson, James Ryan 
and Özlem Türeci for the year ended December 31, 2023 amounted to 
€315,000; €270,000; €270,000; €270,000; €270,000; €90,000; and 
€270,000, respectively.

During the year ended December 31, 2023, upon the recommendation of 
the Compensation, Nomination and Corporate Governance Committee, 
the Supervisory Board approved a special payment in the gross amount 
of €600,000 to Jens Holstein. The special payment was made to honor 
Jens Holstein’s contribution to the extraordinary financial performance 
of  BioNTech  and  recognize  his  efforts  to  strengthen  the  Company’s 
long-term financial performance. Of this payment, Jens Holstein used 
€150,000 net of costs and expenses to purchase 1,620 BioNTech shares 
during the year ended December 31, 2023 to further strengthen his long-
term commitment.

During the year ended December 31, 2023, as part of his appointment to 
the Management Board, James Ryan received a one-time signing cash 
payment in the amount of €180,000. The one-time signing cash payment 
provided compensation in lieu of participation in the LTI 2023 program, 
which was allocated before his appointment, and a pro-rata allocation 
for 2023 would not have been permitted under our current AGM authori-
zations, as ESOPs may only be issued within the first six months of each 
calendar year. Of this payment, James Ryan shall use 50% net of costs 
and expenses to purchase BioNTech shares on or before August 31, 2024 
to further strengthen his long-term commitment. 

2023 and 2022. Effective March 1, 2022, Özlem Türeci’s annual fixed com-
pensation was increased from €360,000 to €550,000. Hence, during the 
years ended December 31, 2023 and 2022, her effective annual fixed 
compensation amounted to €550,000 and €518,333, respectively. The 
increase in the fixed compensation payable to Sean Marett, Ryan Rich-
ardson and Özlem Türeci increased to €550,000 to align with the fixed 
compensation payable to Jens Holstein under his 2021 service agree-
ment, which was considered necessary and in the Company's interest to 
retain our existing Management Board members. All of the Management 
Board members’ activities for BioNTech Group companies are compen-
sated by their base compensation of €550,000 and in the case of Ugur 
Sahin, €700,000.

5.3 Short-Term Incentive Compensation (STI)

The STI is a performance-related bonus with a one-year assessment 
period. The compensation system provides for STI amounts up to a max-
imum of 60% of the amount of the fixed compensation per year. The pay-
out amount of the short-term incentive compensation depends on the 
achievement of certain financial and non-financial performance criteria 
of the Group in a particular financial year, which goals are set uniformly for 
all members of the Management Board. The Supervisory Board exercises 
reasonable discretion in determining whether such criteria have been 
achieved. A detailed description of the STI and potential performance 
targets are included in our compensation system.

During  the  year  ended  December  31,  2022,  the  maximum  short-term 
incentive compensation for each of Ugur Sahin, Jens Holstein, Sean Ma-
rett, Sierk Poetting, Ryan Richardson and Özlem Türeci was €180,000; 
€300,000;  €300,000;  €300,000;  €170,000;  and  €300,000,  respec-
tively, which, considering the 2022 target achievement of 85%, led to 
respective annual bonus amounts of €153,000; €255,000; €255,000; 
€255,000;  €144,500;  and  €255,000.  Following  the  extension  of  their 
respective service agreements and in line with the changes in their annual 
fixed compensation, the maximum short-term incentive compensation 
for Ugur Sahin and Ryan Richardson was increased to €350,000 and 
€300,000 respectively. Following his appointment to the Management 
Board as of September 1, 2023, the maximum short-term compensa-
tion for James Ryan was defined on a pro-rata basis and amounted to 
€100,000 for the year ended December 31, 2023. Based on the 2023 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

231

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

The following table summarizes the overall target achievement and the 
resulting annual bonus payout amount per Management Board member.

Short-Term Incentive Compensation (STI) 
for the year ended December 31, 2023

Relative to fixed 
compensation  
(in %)

Lower Limit  
(0%)

Upper Limit  
(100%)

Overall Target 
Achieve-ment  
(in %)

Thereof First  
Installment to  
be paid out  
in April 2024

Thereof Second 
Installment deferred 
and to be paid out in 
February 2025(1)

Compensation Corridor

STI Payment (in thousand)

Prof. Ugur Sahin, M.D.

Jens Holstein

Sean Marett

Sierk Poetting, Ph.D.

Ryan Richardson

James Ryan, Ph.D.(2)

Prof. Özlem Türeci, M.D.

50

55

55

55

55

55

55

—

—

—

—

—

—

—

350

300

300

300

300

100

300

90

90

90

90

90

90

90

158

135

135

135

135

45

135

158

135

135

135

135

45

135

(1)   Deferred amount is dependent on the share price development during the year following the determination date in Februar 2024. 

(2)  Appointed effective as of September 1, 2023. 

The performance targets defined by our Supervisory Board for the year 
ended December 31, 2023 are related both to our financial performance 
and to our strategic and operational objectives, as we aim to advance our 
pipeline into market readiness. As shown in the table below, the ambitious 
and measurable financial and non-financial performance targets include 
various Company Goals as well as Environmental, Social and Corporate 
Governance, or ESG, targets and were defined in line with the applicable 
compensation system. 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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232

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

The Supervisory Board made the following determinations at the begin-
ning of the 2024 financial year.

Company Goals

Achieve financial targets

Performance Targets 2023 Financial Year

Accelerate Oncology Pipeline

Expand Comirnaty Franchise

Advance technological and manufacturing capabilities

ESG Targets

Enable entrepreneurial spirit at scale, care for people and culture and achieve highest 
quality, CSR and compliance standards

Additional Incentives

Achievements with significant value for the company that were not planned or known at 
the beginning of 2023

Total

Target Performance 
(in %)

Level of Target 
Achievement  
(in %)

Achieved Target 
Performance  
(in %)

30%

20%

18%

16%

31%

10%

125%

53%

75%

100%

81%

84%

20%

16%

15%

18%

13%

26%

2%

90%

During the year ended December 31, 2023, we advanced and diversified 
our innovation pipeline to serve a larger patient population; in particular, 
we advanced our mid- to late-stage oncology and our infectious disease 
pipeline by progressing various programs into and within the clinic. Fur-
thermore, we continued to help fight the pandemic by broadening access 
to Comirnaty worldwide. We also advanced our technological and manu-
facturing capabilities with different construction projects worldwide and 
became a leading artificial intelligence and machine learning company 
with the acquisition of InstaDeep. While we went from a pandemic to an 
endemic market situation and continued investing into our pipeline, we 
were able to remain profitable during the 2023 financial year and ended 
with a €17.7 billion cash and security investment balance as of December 
31, 2023. Additionally, during the year ended December 31, 2023 we fur-
ther improved our governance to achieve and maintain highest possible 
quality, CSR and compliance standards. Furthermore, we continued our 
Company's growth strategy, by elevating our corporate function, hiring 
qualified personnel and caring for our people. The determination on the 
actual achievement of the performance targets by the Supervisory Board 
for the year ended December 31, 2023 was 90%. 

The first installment of the STI for the year ended December 31, 2023 will 
be paid out in April 2024, the month after the approval of the consolidated 
financial statements. The first installment of the STI for the year ended De-
cember 31, 2023 was considered granted and owed in 2023, the year in 
which the activity to which the compensation relates, was performed. The 
first installment of the STI for the year ended December 31, 2022 was con-
sidered granted and owed in 2022 and was paid out in April 2023.

The  second  installment  of  the  STI  for  the  year  ended  December  31, 
2023 was also considered granted and owed in 2023, as the Manage-
ment Board had already completed the activity to which it relates. It will be 
paid out in February 2025 subject to an adjustment due to the share-price 
development. The second installment of the STI for the year ended De-
cember 31, 2022 was considered granted and owed in 2022 and was paid 
out in March 2024 with adjustments due to the share-price development. 

The second STI installment is subject to adjustments in relation to the 
development of the share price between the determination date, when 
the STI achievement is determined, and the respective anniversary of 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

233

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

that date (i.e., in the event of an increase or decrease in the share price, 
based on the market price of ADSs representing our ordinary shares, 
the payment amount is multiplied by the factor of the development of the 
share price). 

Outlook for the 2024 Short-Term Incentive Compensation
For the year ending December 31, 2024 the Supervisory Board defined 
the following performance targets and their weighting for all Management 
Boards Members. The building blocks of the ambitious and measurable 
financial and non-financial performance targets comprise various Com-
pany Goals as well as an Environmental, Social and Corporate Gover-
nance-targets and Additional Incentives. Each of the performance targets 
containing sub-targets with a relative weighting that adds to a maximal 
total achievable target of 125%, whereby the maximum payout on the STI 
is capped at 100% . 

Performance Targets 2024  
Financial Year

Target Performance 
(in %)

Company Goals

Maintain sustainable Financials targets

Continue to build a competitive commercial 
business

Advance pipeline towards market

ESG Targets

Further improve ESG & Global Health 
impact

Additional Incentives Rewards for achievements at the discretion-

of the Supervisory Board

Total

15%

15%

65%

20%

10%

125%

5.4  Share-Based Payments (incl. Long-Term Incentive (LTI) and other 

one-time awards)

Our Management Board’s service agreements provide for long-term in-
centive compensation (Management Board Grant - LTI) through an annual 
grant of options to acquire BioNTech shares during their respective service 
periods. These LTI awards are in line with our compensation system ap-
proved by the AGM on June 22, 2021. The options granted each year are 
subject to the terms and conditions of the respective authorizations of the 
Annual General Meeting creating our Employee Stock Ownership Plan 
(ESOP) and the applicable option agreements thereunder (see section 5.5 
below). 

During the year ended December 31, 2022, the number of options granted 
to Ugur Sahin, Jens Holstein, Sean Marett, Sierk Poetting, Ryan Richardson 
and Özlem Türeci was calculated based on a target value of €750,000; 
€550,000; €550,000; €550,000; €280,000; and €550,000, respectively. 
Beginning on January 1, 2023, the target for the number of options to be 
granted each year for Ugur Sahin and Ryan Richardson was increased 
to a value of €1,050,000 and €550,000, respectively, as part of an annual 
compensation review to ensure competitive compensation. As a result, 
the number of options granted to Ugur Sahin, Jens Holstein, Sean Ma-
rett, Sierk Poetting, Ryan Richardson and Özlem Türeci was calculated 
based on a target value of €1,050,000; €550,000; €550,000; €550,000; 
€550,000;  and  €550,000,  respectively.  The  service  agreement  with 
James Ryan provides that granted options will generally be calculated 
based on a target value of €550,000. However, as the annual grant is gen-
erally made in the first half of the year, no LTI was granted for the period 
from his appointment on September 1, 2023 to December 31, 2023. 

The Supervisory Board granted Jens Holstein a one-time signing bonus of 
€800,000 in connection with his appointment in the form of 4,246 phan-
tom shares. The phantom shares vest in four equal installments on July 1 
of 2022, 2023, 2024, and June 30, 2025 but will only be settled in cash on 
July 1, 2025. The cash payment is subject to an effective settlement clos-
ing price cap. This means that the settlement closing price shall effectively 
be adjusted to ensure that the current price of an ADS as of the settlement 
date does not exceed 800% of the closing price applied when the award 
was initially granted. In addition, the total cash payment under the award 
shall not exceed €6.4 million. 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

234

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

We have also entered into one-time share-based payment arrangements 
with our Management Board members, including the Employee Stock 
Ownership Plan (ESOP) granted in 2018 (ESOP 2018 Program) and the 
Chief Executive Officer Grant granted in 2019 (CEO Grant 2019), which 
are explained in detail in section 5.5 below. 

from USD to Euro using the exchange rates published by the German 
Central Bank (Deutsche Bundesbank) on the same days, as well as using 
the effective exercise price and maximum cap mechanism for all Manage-
ment Board members. The implied market value may vary from the benefit 
in kind.

5.5 Additional Disclosures on Share-Based Payment Instruments

In accordance with Sec. 162 para. 1 no. 3 AktG, the table below provides 
an overview of the share options and other share-based payment instru-
ments allocated to our Management Board and outstanding as of Decem-
ber 31, 2023. 

During the year ended December 31, 2022, option rights granted under the 
ESOP 2018 vested and became exercisable on September 16, 2022 for 
James Ryan, and on November 15, 2022 for Ugur Sahin, Sierk Poetting and 
Sean Marett. The option rights granted to Ryan Richardson and Özlem 
Türeci, which had vested in 2019 but were subject to performance and 
waiting conditions, became exercisable on September 16, 2022 and No-
vember 15, 2022, respectively. During the exercise period, the options 
rights remain subject to performance conditions which must be fulfilled as 
of the date the relevant option rights are exercised. Following the vesting 
of 25% on an annual basis since 2019, the CEO Grant 2019 vested and be-
came exercisable on October 9, 2023. In addition, the various LTI awards 
vest at a rate of 25% annually over four years. The annual vesting dates 
starting the year after the options were awarded are as follows: February 
13 for the LTI 2020 award, May 12 (for all Management Board members 
except Jens Holstein; May 17 for Jens Holstein) for the LTI 2021 award, 
May 31 for the LTI 2022 award, and May 22 for the LTI 2023 award. While 
vesting, the LTI awards continue to be subject to performance and waiting 
conditions. Jens Holstein’s one-time signing bonus also vests at a rate of 
25% annually over four years until June 30, 2025. The award continues to 
be subject to waiting conditions over the vesting period. 

The benefits from our share-based payment arrangements (including 
long-term incentive) are considered granted and owed when the awards 
are settled. For further explanations, see section 5.6. During the years 
ended December 31, 2023 and 2022, this definition applies to the option 
rights granted under the ESOP 2018 Program as a result of their exercise 
and settlement. Although the entire CEO Grant 2019 became exercisable 
during the year ended December 31, 2023, it was not considered granted 
and owed, as it was not actually exercised and remains accessible. With 
respect to the ESOP 2018 Program, the table "Compensation Granted 
and Owed" in section 5.6 shows the implied market value calculated using 
the closing price of an American Depositary Share of BioNTech on Nas-
daq on the respective last day preceding the exercise dates converted 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

235

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

Prof. Ugur Sahin, M.D.

Jens Holstein 

Sean Marett

Sierk Poetting, Ph.D.

Ryan Richardson 

James Ryan, Ph.D.(7)

Prof. Özlem Türeci, M.D.

Grant Date/ 
Allocation Date

10/09/2019(2)

2/13/2020(3)

5/12/2021(4)

5/31/2022(5)

5/20/2023(6)

5/17/2021(4)

7/1/2021(8)

5/31/2022(5)

5/20/2023(6)

11/15/2018

2/13/2020(3)

5/12/2021(4)

5/31/2022(5)

5/20/2023(6)

2/13/2020(3)

5/12/2021(4)

5/31/2022(5)

5/20/2023(6)

2/13/2020(3)

5/12/2021(4)

5/31/2022(5)

5/20/2023(6)

12/15/2020

12/10/2021

12/09/2022

12/08/2023

2/13/2020(3)

5/12/2021(4)

5/31/2022(5)

5/20/2023(6)

Number of Ordinary  
Shares Underlying Share 
Options/Number of  
Phantom Share Options(1)

4,374,963

97,420

17,780

19,997

38,506

6,463

4,246

14,664

18,416

—

38,968

7,112

14,664

18,416

38,968

7,112

14,664

18,416

33,772

6,163

7,465

18,416

1,163

313

740

750

38,968

7,112

14,664

18,416

Option Exercise  
Price (€)(11)

Earliest Option 
Exercise Date(9)

Option  
Expiration Date

Name of  
the Program

13.57

27.86

167.63

137.65

103.12

169.08

n/a(8)

137.65

103.12

10.14

27.86

167.63

137.65

103.12

27.86

167.63

137.65

103.12

27.86

167.63

137.65

103.12

n/a

n/a

n/a

 n/a 

27.86

167.63

137.65

103.12

10/9/2023

2/13/2024

5/12/2025

5/31/2026

5/20/2027

5/17/2025

7/1/2025(8)

5/31/2026

5/20/2027

11/15/2022

2/13/2024

5/12/2025

5/31/2026

5/20/2027

2/13/2024

5/12/2025

5/31/2026

5/20/2027

2/13/2024

5/12/2025

5/31/2026

5/20/2027

12/15/2024

12/10/2025

12/9/2026

12/8/2027

2/13/2024

5/12/2025

5/31/2026

5/20/2027

10/9/2029

CEO Grant 2019

2/13/2030

5/12/2031

5/31/2032

5/20/2033

5/17/2031

LTI 2020(10)

LTI 2021(10)

LTI 2022(10)

LTI 2023(10)

LTI 2021(10)

n/a(8)

Signing Bonus

5/31/2032

5/20/2033

11/15/2026

2/13/2030

5/12/2031

5/31/2032

5/20/2033

2/13/2030

5/12/2031

5/31/2032

5/20/2033

2/13/2030

5/12/2031

5/31/2032

5/20/2033

n/a

n/a

n/a

n/a

2/13/2030

5/12/2031

5/31/2032

5/20/2033

LTI 2022(10)

LTI 2023(10)

ESOP 2018

LTI 2020(10)

LTI 2021(10)

LTI 2022(10)

LTI 2023(10)

LTI 2020(10)

LTI 2021(10)

LTI 2022(10)

LTI 2023(10)

LTI 2020(10)

LTI 2021(10)

LTI 2022(10)

LTI 2023(10)

LTI 2020 (EEP)

LTI 2021 (EEP)

LTI 2022 (EEP)

LTI 2023 (EEP)

LTI 2020(10)

LTI 2021(10)

LTI 2022(10)

LTI 2023(10)

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

236

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

(1)  The 18-for-1 stock split of our ordinary shares, which became effective on September 18, 2019 upon 

registration with the commercial register (Handelsregister) is reflected in share amounts granted in 

advance.

(2)  Options vested in four equal installments on October 9 of 2020, 2021, 2022 and 2023. With the final 

installment vesting in 2023, the entire award became exercisable. As Ugur Sahin did not exercise in 2023, 

the options remain exercisable and can only be exercised during the exercise windows as defined by our 

ESOP.

(3)  Options vested in four equal installments on February 13 of 2021, 2022, 2023 and 2024, and are now 

exercisable following the expiry of the waiting period on February 13, 2024 and can only be exercised 

during the exercise windows as defined by our ESOP.

(4)  Options were issued as phantom share options and vest in four equal installments on May 12 of 2022, 

2023, 2024 and 2025 for all Management Board members except Jens Holstein, and in the case of 

Jens Holstein, vest in four equal installments on May 17 of 2022, 2023, 2024 and 2025. The options 

will not become exercisable before the expiry of the waiting period on May 12, 2025 and May 17, 2025, 

respectively, and can only be exercised during the exercise windows as defined by our ESOP. 

(5)  Options were issued as phantom share options and vest in four equal installments on May 31 of 2023, 

2024, 2025 and 2026 for all Management Board members. The options will not become exercisable 

before the expiry of the waiting period on May 31, 2026 and can only be exercised during the exercise 

windows as defined by our ESOP. 

(6)  Options vest in four equal installments on May 20 of 2024, 2025, 2026 and 2027. The options will not 

become exercisable before the expiry of the waiting period on May 20, 2027 and can only be exercised 

during the exercise windows as defined by our ESOP. 

(7)  As James Ryan was not part of the Management Board at the time the 2023 LTI award was allocated, 

he did not receive any options under the ESOP. Prior to his appointment to the Management Board, 

RSUs were granted to him under the BioNTech 2020 Employee Equity Plan (EEP). RSUs issued under 

the LTI 2020 (EEP), LTI 2021 (EEP), LTI 2022 (EEP) and LTI 2023 (EEP) programs vest annually in equal 

installments over four years commencing in December 2020, December 2021, December 2022 and 

December 2023 respectively and will be settled after a waiting period of four years. 

(8)  In connection with Jens Holstein’s appointment to the Management Board as Chief Financial Officer 

(CFO) as of July 1, 2021, the Supervisory Board granted him a one-time signing bonus as outlined in 

section 5.4. n/a = not applicable

(9)  Indicates end of the respective waiting periods, additional restrictions with respect to exercise windows 

may apply.

(10) Management Board Grant (Long-Term Incentive) in the respective years. 

(11)  All options are subject to an effective exercise price cap. This means that the exercise price shall 

effectively be adjusted to ensure that the current price of an ADS as of the exercise does not exceed 

800% of the exercise price. With respect to the ESOP 2018 Program and the CEO Grant 2019, the 

maximum economic benefit receivable in respect of any exercised is capped at $240.00 with the effective 

exercise price being capped at a Euro amount equivalent to $30.00. With respect to the LTI 2020, the 

maximum economic benefit receivable in respect of any exercised option is capped at $246.24, with the 

effective exercise price being capped at a Euro amount equivalent to $30.78. With respect to the phantom 

share options issued under the LTI 2021 and 2022 as well as the options issued under the LTI 2023 

programs, the maximum compensation that the Management Board members are entitled to receive 

under such programs, together with other compensation components received by each such board 

member in the respective grant year, shall not exceed €20.0 million for Ugur Sahin as Chief Executive 

Officer (CEO) and €10.0 million  for all other Management Board members. 

Management Board Grant (Long-Term Incentive)
Our Management Board’s service agreements provide for long-term in-
centive compensation (Management Board Grant - LTI) through an an-
nual grant of options to acquire BioNTech shares during their respective 
service periods. The options granted each year are subject to the terms 
and conditions of the respective authorizations of the Annual General 
Meeting creating our Employee Stock Ownership Plan (ESOP) and the 
applicable option agreements thereunder. The allocation of the number 
of issued options in 2020 occurred in February 2020. In May 2021 and 
May 2022, the Management Board received phantom options equivalent 
to the number of options the Management Board members would have 
been entitled to receive for 2021 and 2022. During 2023, options were 
granted in May 2023. 

For the awards allocated as of February 13, 2020; May 12, 2021; May 17, 
2021; May 31, 2022 and May 20, 2023, the exercise prices are $30.78 
(€27.86);  $185.23  (€167.63);  $186.83  (€169.08);  $152.10  (€137.65)and 
$113.94 (€103.12) respectively (all amounts calculated as of December 31, 
2023 using the foreign exchange rate as published by the German Central 
Bank (Deutsche Bundesbank)).

All options are subject to an effective exercise price cap, which means that 
the exercise price shall be adjusted to ensure that the current price of an 
ADS as of the exercise date does not exceed 800% of the exercise price. 
With respect to the LTI 2020, the maximum economic benefit receivable 
in respect of any exercised option is capped at $246.24, with the effective 
exercise price being capped at a Euro amount equivalent to $30.78. With 
respect to the phantom share options issued under the LTI 2021 and 2022 
as well as the options issued under the LTI 2023 programs, the maximum 
compensation that the Management Board members are entitled to re-
ceive under such programs, together with other compensation compo-
nents received by each such board member in the respective grant year, 
shall not exceed €20.0 million for Ugur Sahin as Chief Executive Officer 
(CEO) and €10.0 million for all other Management Board members. The 
options vest annually in equal installments over four years commencing 
on the first anniversary of the allocation date and become exercisable four 
years after the allocation date. 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

237

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

The vested options can only be exercised if each of the following perfor-
mance criteria has been achieved: (i) at the time of exercise, the current 
price is equal to or greater than the threshold amount (that is, the exercise 
price, provided that such amount increases by seven percentage points 
on each anniversary of the allocation date); (ii) at the time of exercise, the 
current price is at least equal to the target price (that is, (a) for the twelve-
month period starting on the fourth anniversary of the allocation date, 
$8.5 billion divided by the total number of the ordinary shares outstanding 
immediately following the initial public offering (other than ordinary shares 
owned by BioNTech), and (b) for each twelve-month period starting on 
the fifth or subsequent anniversary of the allocation date, 107% of the 
target share price applicable for the prior twelve-month period); and (iii) 
the closing price for the fifth trading day prior to the start of the relevant 
exercise window is higher than the exercise price by at least the same 
percentage by which the Nasdaq Biotechnology Index or a comparable 
successor index as of such time is higher than such index was as of the 
last trading day before the allocation date. Following the expiry of the wait-
ing period, option rights may be exercised during the exercise windows as 
set out in the ESOP agreement. The option rights can be exercised up to 
ten years after the allocation date. If they have not been exercised by that 
date, they will be forfeited without compensation. 

The tables below show the development and the outstanding number of 
share options as of and between the dates indicated: 

Management Board Grant (LTI 2020)

Number of Ordinary Shares 
Underlying Share Options

As of December 31, 2022

Exercised

As of December 31, 2023

Prof. Ugur  
Sahin, M.D.

97,420

—

97,420

Jens Holstein(1)

Sean Marett

Sierk  
Poetting, Ph.D.

Ryan Richardson

James  
Ryan, Ph.D.(2)

Prof. Özlem  
Türeci, M.D.

—

—

—

38,968

—

38,968

38,968

—

38,968

33,772

—

33,772

—

—

—

38,968

—

38,968

(1)  Jens Holstein was appointed to the Management Board as Chief Financial Officer (CFO) as of July 1, 2021, subsequent to the allocation of the Management Board Grant (LTI 2020). 

(2)  James Ryan was appointed to the Management Board as Chief Legal Officer (CLO) as of September 1, 2023, subsequent to the allocation of the Management Board Grant (LTI 2020). 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

238

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

Management Board Grant (LTI 2021)

 Number of Phantom Share Options 

As of December 31, 2022

Exercised

As of December 31, 2023

Prof. Ugur  
Sahin, M.D.

17,780

—

17,780

Jens Holstein

Sean Marett

Sierk  
Poetting, Ph.D.

Ryan Richardson

James  
Ryan, Ph.D.(1)

Prof. Özlem  
Türeci, M.D.

6,463

—

6,463

7,112

—

7,112

7,112

—

7,112

6,163

—

6,163

—

—

—

7,112

—

7,112

(1)  James Ryan was appointed to the Management Board as Chief Legal Officer (CLO) as of September 1, 2023, subsequent to the allocation of the Management Board Grant (LTI 2021). 

Management Board Grant (LTI 2022)

 Number of Phantom Share Options 

As of December 31, 2022

Exercised

As of December 31, 2023

Prof. Ugur  
Sahin, M.D.

19,997

—

19,997

Jens Holstein

Sean Marett

Sierk  
Poetting, Ph.D.

Ryan Richardson

James  
Ryan, Ph.D.(1)

Prof. Özlem  
Türeci, M.D.

14,664

—

14,664

14,664

—

14,664

14,664

—

14,664

7,465

—

7,465

—

—

—

14,664

—

14,664

(1)  James Ryan was appointed to the Management Board as Chief Legal Officer (CLO) as of September 1, 2023, subsequent to the allocation of the Management Board Grant (LTI 2022).

Management Board Grant (LTI 2023)

 Number of Share Options 

As of December 31, 2022

Allocated

Exercised

As of December 31, 2023

Prof. Ugur  
Sahin, M.D.

—

38,506

—

38,506

Jens Holstein

Sean Marett

Sierk  
Poetting, Ph.D.

Ryan Richardson

James  
Ryan, Ph.D.(1)

Prof. Özlem  
Türeci, M.D.

—

18,416

—

18,416

—

18,416

—

18,416

—

18,416

—

18,416

—

18,416

—

18,416

—

—

—

—

—

18,416

—

18,416

(1)  James Ryan was appointed to the Management Board as Chief Legal Officer (CLO) as of September 1, 2023, subsequent to the allocation of the Management Board Grant (LTI 2023).

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

239

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

The following is a presentation of the one-time programs that were 
approved prior to the adoption of the compensation system during the 
year ended December 31, 2021:

windows as defined by our ESOP. The option rights can be exercised up 
to ten years after the allocation date. If they have not been exercised by 
that date, they will be forfeited without compensation.

Chief Executive Officer Grant 2019
In  September  2019,  we  granted  Ugur  Sahin  an  option  to  purchase 
4,374,963 of our ordinary shares, subject to his continuous employment 
with us. The exercise price per share of each option is $15.00 (€13.57), 
being the public offering price from our initial public offering converted 
into Euros as of December 31, 2023, and which is subject to the effective 
exercise price cap and the maximum cap mechanism. Under the effective 
exercise price cap, the exercise price shall be adjusted to ensure that the 
current price of an ADS as of the exercise date does not exceed 800% 
of the exercise price. Under the maximum cap mechanism, the maximum 
economic benefit receivable in respect of any exercised option is capped 
at $240, with the effective exercise price being capped at a Euro amount 
equivalent to $30.00. Under this CEO Grant, the options vested annually 
in equal installments over four years commencing on the first anniversary 
of our initial public offering. 

The vested option rights can only be exercised if and to the extent that 
each of the following performance criteria has been achieved: (i) at the 
time of exercise, the current price is equal to or greater than the threshold 
amount (that is, the exercise price, provided that such amount increases 
by seven percentage points on each anniversary of the allocation date); 
(ii) at the time of exercise, the current price is at least equal to the target 
price (that is, (a) for the twelve-month period starting on the fourth anni-
versary of the allocation date, $8.5 billion divided by the total number of 
the shares outstanding immediately following the initial public offering 
(other than shares owned by us), and (b) for each twelve-month period 
starting on the fifth or subsequent anniversary of the allocation date, 107% 
of the target share price applicable for the prior twelve-month period); 
and (iii) the closing price for the fifth trading day prior to the start of the 
relevant exercise window is higher than the exercise price by at least the 
same percentage by which the Nasdaq Biotechnology Index or a com-
parable successor index as of such time is higher than such index was 
as of the last trading day before the allocation date. Following the expiry 
of the waiting period, option rights may be exercised during the exercise 

On October 9, 2023, with the final installment vesting, all 4,374,963 op-
tions became exercisable under the rules of the ESOP and the ESOP 
agreement. During the year ended December 31, 2023, no options were 
exercised.

Employee Stock Ownership Plan 2018
Based on an authorization of the general meeting on August 18, 2017, we 
established a share option program under which we granted selected 
employees options to receive our shares. The program is designed as 
an Employee Stock Ownership Plan, or ESOP. We offered participants 
a certain number of option rights by their explicit acceptance of an op-
tion rights agreement. The exercise of option rights in accordance with 
the agreement gives the participants the right to obtain shares against 
payment of the exercise price. With respect to the Management Board 
members serving at the time of allocation, the options are subject to the 
effective exercise price cap and maximum cap mechanisms. Under the 
exercise price cap, the exercise price shall be adjusted to ensure that the 
current price of an ADS as of the exercise date does not exceed $30.00. 
Under the ESOP, the option rights (other than Özlem Türeci’s, and Ryan 
Richardson’s options) fully vest after four years and can be exercised 
if: (i) the waiting period of four years has elapsed; and (ii) at the time of 
exercise, the average closing price of the shares of the Company or the 
average closing price of the right or certificate to be converted into an 
amount per share on the previous ten trading days preceding the exercise 
of the option right exceeds the strike price by a minimum of 32%, with this 
percentage increasing by eight percentage points as of the fifth anniver-
sary of the respective issue date and as of each subsequent anniversary 
date. Following the expiry of the waiting period, option rights may be ex-
ercised within a period of four weeks from the date of the Annual General 
Meeting or the publication of the annual financial statements, the semi-an-
nual report or our most recent quarterly report or interim report (exercise 
windows). The option rights can be exercised up to eight years after the 
allocation date. If they have not been exercised by that date, they will be 
forfeited without compensation. 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

240

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

By way of a shareholders’ resolution of the general meeting on August 
19, 2019, the authorization to issue such option rights was amended such 
that, in order for the options to be exercisable, the average closing price 
of the Company’s shares or the average closing price of the right or cer-
tificate to be converted into an amount per share on the ten trading days 
immediately preceding the exercise must exceed the strike price by a 
minimum of 28%, with this percentage increasing by seven percentage 
points as of the fifth anniversary of the issue date and as of each subse-
quent anniversary date. Furthermore, in addition to the aforementioned 
requirements, the exercise is only possible if the share price (calculated 
by reference to the price of the ordinary share underlying the ADS) has 
performed similar to or better than the Nasdaq Biotechnology Index. The 
changes made do not affect option rights already issued.

In September 2022, the Supervisory Board determined the ESOP settle-
ment by the delivery of treasury shares (in the form of ADSs) equal to the 
net value of the exercised option rights after deduction of (i) the exercise 
price and (ii) the applicable wage taxes (including solidarity surcharge 
thereon and church tax, if applicable) and social security contributions 
resulting from such exercise. The settlement was applied during the exer-
cise windows in 2022 and 2023. 

The table below shows the development and the outstanding number of 
share options as of and between the dates indicated: 

ESOP 2018

Number of Ordinary Shares 
Underlying Share Options

As of December 31, 2022

Exercised

As of December 31, 2023

Prof. Ugur  
Sahin, M.D.

Jens Holstein(1)

Sean Marett

Sierk  
Poetting, Ph.D.

Ryan Richardson

James  
Ryan, Ph.D.(2)

Prof. Özlem  
Türeci, M.D.

—

—

—

—

—

—

230,780

(230,780)

—

—

—

—

—

—

—

—

—

—

—

—

—

(1)  Jens Holstein was appointed to the Management Board as Chief Financial Officer (CFO) as of July 1, 2021. 

(2)  James Ryan was appointed to the Management Board as Chief Legal Officer (CLO) as of September 1, 2023. 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

241

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

Except for Sean Marett, all Management Board members exercised all 
their option rights during the year ended December 31, 2022. Sean Marett 
exercised his remaining 230,780 option rights in 2023. The members of 
the Management Board do not have any options from the ESOP 2018 
program outstanding as of December 31, 2023. The members of the Man-
agement Board have mainly retained most of the shares resulting from the 
settlement and therefore hold an important stake in our company's future. 

5.6  Compensation Granted and Owed during the year ended 

December 31, 2023

The total compensation granted or owed according to Sec. 162 para. 
1 AktG to all members of the Management Board for the years ended 
December  31,  2023,  and  2022  is  presented  in  the  table  below.  Com-
pensation is considered granted if it either has been actually received or 
the activities to which it relates have been performed. Compensation is 
considered owed if the compensation components are legally due, but 
have not yet been received. Hereinafter, when the former definition ap-
plies, compensation is referred to only as being “granted and owed.” The 
Institute of Public Auditors in Germany, Incorporated Association  (Institut 
der Wirtschaftsprüfer, IDW) has provided two interpretations for the pre-
sentation.  According  to  interpretation  1,  compensation  is  only  shown 
as granted and owed in the year in which it is received (inflow principle; 
 “Zuflussprinzip”). According to interpretation 2, compensation may also 
be disclosed in the compensation report for the financial year in which the 
activity underlying the compensation was performed (vesting principle; 
“Erdienungsprinzip”). The Supervisory Board and the Management Board 
have decided to apply interpretation 2 for short-term compensation com-
ponents such as fixed compensation and short-term incentives (STI) and 
interpretation  1  for  share-based  payments  (incl.  long-term  incentives 
(LTI)).  An  approach  which  deviates  from  interpretation  1  was  chosen 
because it allows a fair presentation of the actual benefits, which are, for 
example, subject to final underlying share price developments. 

As outlined in section 5.4, during the year ended December 31, 2022, 
the options granted under the ESOP 2018 Program vested and became 
exercisable (option rights allocated to Ryan Richardson and Özlem Türeci 
had already vested in 2019, but continued to be subject to performance 
and waiting conditions). During the year ended December 31, 2023, the 

options granted under the CEO Grant 2019 vested and became exercis-
able. During the exercise period, the options rights remain subject to per-
formance conditions which have to be fulfilled as of the date the relevant 
option rights are exercised. The benefits from our share-based payment 
arrangements (including long-term incentive) are considered granted and 
owed when the awards are settled. During the years ended December 31, 
2023 and 2022, this definition applies to the option rights granted under 
the ESOP 2018 Program as a result of their exercise and settlement. Al-
though the entire CEO Grant 2019 became exercisable during the year 
ended December 31, 2023, it was not considered granted and owed, as it 
was not actually exercised and remains accessible. 

The amounts shown as share-based payments (including long-term in-
centives)  in  the  table  below  are  based  on  the  implied  market  value  at 
the time the awards fulfill the “granted and owed” definition. The ESOP 
2018 Program, designed in line with market standards, comprises provi-
sions as outlined in section 5.5 above that include effective exercise price 
cap and maximum cap mechanisms. Although those cap mechanisms 
were applied, our unique and outstanding share price development be-
tween the time of grant and settlement, led to extraordinary high amounts, 
as shown below. The share price was driven by our extraordinary rev-
enues and net profit increases at that time. While unprecedented and 
driven by the COVID-19 pandemic, these developments were also largely 
attributable to the exceptional performance and contribution of the Man-
agement Board as a whole, including their determination to help fight the 
pandemic since early 2020. They are not to be seen as cash payments to 
the Management Board, as the exercise was settled by delivering Amer-
ican Depositary Shares, or ADSs, representing our ordinary shares. The 
members of the Management Board have mainly retained most of the 
shares resulting from the after-tax settlement and therefore hold an im-
portant stake in our Company’s future. 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

242

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

in thousands €

Fixed compensation(1)

2023

2022

Fringe benefits(3)

2023

2022

Short-term incentive –  
first installment(4)

2023

2022

Short-term incentive –  
second installment(5)

2023

2022

Other variable compensation

2023

2022

Share-based payments  
(incl. long-term incentive)(8)

2023

Management Board Grant – LTI 

ESOP 2018(9)

Other share-based payment arrangements

2022

Management Board Grant – LTI

ESOP 2018(9)

Other share-based payment arrangements

Total

2023

2022

Prof. Ugur  
Sahin, M.D.

Jens Holstein

Sean Marett

Sierk  
Poetting, Ph.D.

Ryan Richardson

James  
Ryan, Ph.D.(2)

Prof. Özlem  
Türeci, M.D.

700

360

6

6

158

77

158

77

—

—

—

—

—

—

257,076

—

1,022

257,596

550

550

5

7

135

128

135

128

600(7)

—

—

—

—

—

—

—

1,425

813

550

513

12

8

135

128

135

128

—

60

—

19,289

—

—

53,479

—

20,121

54,316

550

550

5

4

135

128

135

128

—

—

—

—

—

—

550

340

26

27

135

72

135

72

—

—

—

—

—

—

86,015

—

825

86,825

22,555

—

846

23,066

183

—

—

—

45

—

45

—

180(6)

—

—

—

—

—

—

—

453

—

550

518

—

—

135

128

135

128

—

—

—

—

—

—

274,209

—

820

274,983

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

243

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

(1)   For James Ryan, a part of the fixed compensation was paid by BioNTech UK Limited, a subsidiary of 

(9)  The amounts shown are related to the option rights granted one-time under the ESOP 2018 Program. The 

BioNTech SE. Approximately 30% of his total compensation is attributable to his position as a member of 

table shows the implied market value calculated using the closing price of an American Depositary Share 

the Management Board and approximately 70% is attributable to his position as a director of BioNTech UK 
Limited.

of BioNTech on Nasdaq on the respective last day preceding the exercise dates converted from USD to 
Euro using the exchange rates published by the German Central Bank (Deutsche Bundesbank) on the 

(2)  James Ryan was appointed to the Management Board as Chief Legal Officer (CLO) effective as of 

same days, as well as using the effective exercise price and maximum cap mechanism for all Management 

September 1, 2023. His compensation for the year ended December 31, 2023 was granted on a pro-rata 

Board members. The implied market value may vary from the benefit in kind.. Our unique and outstanding 

basis. 

share price development between the time of grant and settlement, led to extraordinary high amounts. 

(3)  Includes social security, health and additional insurance, company bike and travel expenses. Other fringe 

They are not to be seen as cash payments to the Management Board, as the exercise was settled by 

benefits, e.g., costs for security services, which are integral to the performance of business duties, are not 

delivering ADSs, representing our ordinary shares. The members of the Management Board have mainly 

included in the amount.

retained most of the shares resulting from the after-tax settlement and therefore hold an important stake 

(4)  The STI in a given year is always paid out in two installments over two years. The first installment of the 

in our Company’s future.

For the years ended December 31, 2023, and 2022 we did not make use 
of the malus and claw-back provisions, which would entitle us to withhold 
or reclaim variable STI compensation components in whole or in part, as 
no event incurred which would be considered a breach in this respect. 

For the years ended December 31, 2023, and 2022, no event of termi-
nation occurred under the Management Board service contracts. As a 
result, we did not apply the termination-related rules and regulations, 
which state that outstanding variable compensation components in the 
period up to termination shall be granted and, in the event of premature 
termination due to revocation of the appointment, the Board member shall 
receive a severance payment. 

A detailed description of the malus and claw-back and termination provi-
sions are included in our compensation system.

STI for the year ended December 31, 2023 will be paid out in April 2024, the month after the approval of 

the consolidated financial statements. The first installment of the STI for the year ended December 31, 

2023 was considered granted and owed in 2023, the year in which the activity to which the compensation 

relates, was performed. The first installment of the STI for the year ended December 31, 2022 was 

considered granted and owed in 2022 and was paid out in April 2023.

(5)  The second installment of the STI for the year ended December 31, 2023 was also considered granted and 

owed in 2023, as the Management Board had already completed the activity to which it relates. It will be paid 

out in February 2025 subject to an adjustment due to the share-price development. The second installment 

of the STI for the year ended December 31, 2022 was considered granted and owed in 2022 and was paid 

out in March 2024 with adjustments due to the share-price development. The amounts ultimately paid 

were as follows: Ugur Sahin €50 thousand, Jens Holstein €83 thousand, Sean Marett €83 thousand, Sierk 

Poetting €83 thousand, Ryan Richardson €47 thousand and Özlem Türeci €83 thousand.

(6)  During the year ended December 31, 2023, as part of his appointment to the Management Board, James 

Ryan received a one-time signing cash payment in the amount of €180,000. The one-time signing cash 

payment provided compensation in lieu of participation in the LTI 2023 program, which was allocated 

before his appointment, and a pro-rata allocation for 2023 would not have been permitted under our 

current AGM authorizations, as ESOPs may only be issued within the first six months of each calendar 

year. Of this payment, James Ryan shall use 50% net of costs and expenses to purchase BioNTech shares 

on or before August 31, 2024 to further strengthen his long-term commitment. 

(7)  During the year ended December 31, 2023, upon the recommendation of the Compensation, Nomination 

and Corporate Governance Committee, the Supervisory Board approved a special payment in the 

gross amount of €600,000 to Jens Holstein. The special payment was made to honor Jens Holstein’s 

contribution to the extraordinary financial performance of BioNTech and recognize his efforts to 

strengthen the Company’s long-term financial performance. Of this payment, Jens Holstein used 

€150,000 net of costs and expenses to purchase 1,620 BioNTech shares during the year ended 

December 31, 2023 to further strengthen his long-term commitment.

(8)  Explanations of our share-based payment arrangements are given in section 5.5 and include the LTI 

arrangements, the ESOP 2018, the CEO Grant 2019 and a one-time signing bonus agreed with Jens 

Holstein as outlined in detail under section 5.4. The benefits from our share-based payment arrangements 

(including long-term incentive) are considered granted and owed when the awards are settled. During 

the years ended December 31, 2023 and 2022, this definition applies to the option rights granted under 

the ESOP 2018 Program as a result of their exercise and settlement. Although the entire CEO Grant 2019 

became exercisable during the year ended December 31, 2023, it was not considered granted and owed, 

as it was not actually exercised and remains accessible. .

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

244

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

E.  INFORMATION ON THE 

RELATIVE DEVELOPMENT 
OF THE COMPENSATION OF 
THE MANAGEMENT BOARD, 
THE COMPENSATION OF 
THE EMPLOYEES AND THE 
DEVELOPMENT OF THE 
COMPANY’S EARNINGS

The table below shows the relative development of the compensation 
granted  and  owed  to  the  Supervisory  Board  and  Management  Board 
members, the average compensation of our employees and selected key 
earning indicators for the periods indicated. 

Selected key earning indicators considered by Sec. 162 para. 1 no. 2 AktG 
generally measure the development of earnings on the basis of revenues, 
operating income of the BioNTech Group (IFRS) and net income (HGB) 
of the Company. Considering our operational and financial development, 
our key earnings indicators fluctuated exceptionally over the past years. 
Therefore, the development of those indicators relative to the compensa-
tion our Supervisory and Management Board members is not considered 
meaningful. 

The compensation of our members of the Management Board significant-
ly changed comparing the 2023 to 2022 and 2022 to 2021 financial years, 
mainly as the options granted one-time under the ESOP 2018 Program 
vested and became exercisable and were almost entirely settled in 2022 
(option rights allocated to Ryan Richardson and Özlem Türeci had already 
vested in 2019 but continued to be subject to performance and waiting 
conditions and only Sean Marett had 230,780 options outstanding as of 
December 31, 2022, which were exercised and settled in May 2023). The 
definition of granted and owed applies to the option rights granted under 

the ESOP 2018 Program, as they were exercised and settled in those 
years ended December 31, 2023 and 2022. Even though the entire CEO 
Grant 2019 became exercisable during the year ended December 31, 
2023, it was not considered granted and owed, as it was not exercised 
and remains accessible. As outlined in section 5.6, the compensation is 
based on the implied market value at the time the options are considered 
granted and owed in terms of Sec. 162 AktG. Our unique and outstanding 
share price development between the time of grant and settlement, led to 
extraordinary high amounts. Therefore, the development of the compen-
sation of the members of the Management Board is mainly not considered 
meaningful.

The presentation of the average compensation of employees is based on 
the compensation of BioNTech Group employees excluding apprentices. 
The average employee compensation is calculated using the average 
full-time equivalent at the beginning and end of the respective period. 
The number of full-time equivalent employees employed by the Group in-
creased from 1,941 as of December 31, 2020 to 3,082 as of December 31, 
2021; 4,530 as of December 31, 2022; and 6,133 as of December 31, 2023. 

In order to be in line with the compensation of the Management Board 
members, the presentation of the workforce compensation also corre-
sponds in principle to the granted and owed compensation within the 
meaning of Section 162 para. 1 sentence 1 AktG and is shown with and 
without share-based payment compensation. The compensation com-
prises the total expenses for wages, benefits and social security contri-
butions. In addition, for our workforce, share-based payment programs 
are considered with their implied market value, to the extent considered 
granted and owed during the years ended December 31, 2023, and 2022 
(which  applies  to  the  ESOP  2018  Program  and  the  LTI-plus  program 
awarded to employees who did not participate in the ESOP 2018 Pro-
gram). The share-based payment compensation was calculated using the 
closing price of an American Depositary Share of BioNTech on Nasdaq 
on the last trading day preceding the various respective exercise dates 
(ESOP 2018 Program) or on December 15, 2022 (LTI-plus settlement 
day) converted from USD to Euro using the exchange rate published by 
the German Central Bank (Deutsche Bundesbank) on the relevant days. 
The implied market values may vary from the benefit in kind. 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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245

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

The compensation of the workforce significantly changed comparing the 
year-on-year development between the 2020 and 2023 financial years, 
as the option rights and restricted stock units granted one-time under the 
ESOP 2018 Program and LTI-plus programs were considered granted 
and owed mainly during the year ended December 31, 2022. Considering 
the compensation of the workforce without the share-based payment 
consideration, the change over the years was impacted by bonus pay-
ments mainly made in 2022. While the base salary from 2021 to 2022 as 
well as 2022 to 2023 increased (10% and 7% respectively), the overall 
compensation decreased from 2022 to 2023 due special one-time bonus 
payments in 2022. The overall compensation was additionally impacted 
by other factors including a changed personnel structure in connection 
with new hires.

In 2023, the average per head target compensation of the Management 
Board amounted to 9-times the average per head target compensation 
of all BioNTech employees (excluding the Management Board) in 2023.

in %

Management Board

Prof. Ugur Sahin, M.D.

Jens Holstein(5)

Sean Marett

Sierk Poetting, Ph.D.

Ryan Richardson

James Ryan, Ph.D.(7)

Prof. Özlem Türeci, M.D.

Supervisory Board

Helmut Jeggle 

Ulrich Wandschneider, Ph.D.

Baroness Nicola Blackwood(1)

Prof. Christoph Huber, M.D.(6)

Prof. Anja Morawietz, Ph.D.(11)

Michael Motschmann

Prof. Rudolf Staudigl, Ph.D.(11)

Earnings indicators

Revenues from contracts  
with customers  
(IFRS BioNTech Group)

Operating income/(loss)  
(IFRS BioNTech Group) 

Net income (HGB BioNTech SE) 

Compensation of the 
 workforce(2)

Total workforce compensation

Total workforce compensation 
excl. share-based payments

Change  
2023  
vs. 2022

Change  
2022  
vs. 2021

Change  
2021  
vs. 2020

n.m.(4)

75

n.m.(4)

n.m.(4)

n.m.(4)

—

n.m.(4)

—

(19)

—

n.m.

n.m.

(16)

n.m.

n.m.(8)

n.m.(9)

n.m.(10)

(67)

(5)

n.m.(4)

n.m.(5)

n.m.(4)

n.m.(4)

n.m.(4)

—

n.m.(4)

24

25

—

36

—

51

—

(9)

(17)

(20)

272

35

—

n.m.(5)

2

2

2

—

(1)

21

18

—

18

—

26

—

n.m.(8)

n.m.(9)

n.m.(10)

17

5

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BioNTech | Annual Report 2023

246

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

(1)  Nicola Blackwood was appointed to the Supervisory Board as of May 23, 2023. Therefore, a comparison 

(8)  Revenues changed significantly from €482,3 million in the year ended December 31, 2020 to 

with the prior year is not possible. 

(2)  The average employee compensation is based on the compensation of BioNTech Group employees 
including social security contributions and the implied market value from share-based payment 

€18,976.7 million during the year ended December 31, 2021, to €17,310.6 million in the year ended 

December 31, 2022 and to €3,819.0 million during the year ended December 31, 2023. 

(9)  Operating profit/(loss) changed significantly from an operating loss of €82,4 million in the year ended 

arrangements, which are considered granted and owed. Considering the compensation of the workforce 

December 31, 2020 to an operating profit of €15,283.8 million during the year ended December 31, 2021 

without the share-based payment consideration, the change over the years was impacted by bonus 

to €12,642.7 million operating profit during the year ended December 31, 2022 and to a €690.4 million 

payments mainly made in 2022. While the base salary from 2021 to 2022 as well as 2022 to 2023 

operating profit during the year ended December 31, 2023. 

increased (10% and 7% respectively), the overall compensation decreased from 2022 to 2023 due to 

(10) Net income (HGB) changed significantly from a €128.4 million net loss during the year ended December 

special one-time bonus payments in 2022. The overall compensation was additionally impacted by other 

31, 2020 to €10,777.6 million net income during the year ended December 31, 2021, to €8,626.0 million 

factors including a changed personnel structure in connection with new hires. The average employee 

net profit during the year ended December 31, 2022 and to €799.5 million net income during the year 

compensation is calculated using the average full-time equivalent at the beginning and end of the periods 

ended December 31, 2023. The information on net income (HGB) is not representative for the Group but is 

indicated. 

(3)  n.m. = not meaningful.

considered to be a key earning indicator in terms of Sec. 162 para. 1 no. 2 AktG. 

(11)  Anja Morawietz and Rudolf Staudigl were appointed to the Supervisory Board as of June 1, 2022. Their 

(4)  The compensation of our members of the Management Board significantly changed comparing the 

compensation for the year ended December 31, 2022 was granted on a pro-rata basis. Therefore, a 

2023 to 2022 and 2022 to 2021 financial years, mainly as the options granted one-time under the ESOP 

comparison with the partial year period is not meaningful (comparing the 2023 and 2022 financial year) or 

2018 Program vested and became exercisable and were almost entirely settled in 2022 (option rights 

not possible (comparing the 2022 and 2021 financial year).

allocated to Ryan Richardson and Özlem Türeci had already vested in 2019 but continued to be subject 

to performance and waiting conditions and only Sean Marett had 230,780 options outstanding as of 

December 31, 2022, which were exercised and settled in May 2023). The definition of granted and owed 

applies to the option rights granted under the ESOP 2018 Program, as they were exercised and settled 

in those years ended December 31, 2023 and 2022. Even though the entire CEO Grant 2019 became 

exercisable during the year ended December 31, 2023, it was not considered granted and owed, as it 

was not exercised and remains accessible. As outlined in section 5.6, the compensation is based on the 

implied market value at the time the options are considered granted and owed in terms of Sec. 162 AktG 

and, our unique and outstanding share price development between the time of grant and settlement, led 

to extraordinary high amounts. Therefore, the development of the compensation of the members of the 

Management Board is mainly not considered meaningful. The compensation changes in % between the 

2022 and 2021 financial year for the members of the Management Board is the following: Ugur Sahin 

47,079, Sean Marett 8,632, Sierk Poetting 15,404, Ryan Richardson 4,550 and Özlem Türeci 50,823. For 

the changes in % between the 2023 and 2022 financial year, the compensation of the Management Board 

is the following: Ugur Sahin (100), Sean Marett (63), Sierk Poetting (99), Ryan Richardson (96) and Özlem 

Türeci (100). 

(5)  Jens Holstein was appointed to the Management Board as Chief Financial Officer (CFO) as of July 1, 2021. 

His compensation for the year ended December 31, 2021 was granted on a pro-rata basis. Therefore, 

a comparison with the prior year is not meaningful (comparing the 2022 and 2021 financial year) or not 

possible (comparing the 2021 and 2020 financial year).

(6)  Christoph Huber, served as a member of our Supervisory Board from 2008 and left the Supervisory 

Board on May 25, 2023 after reaching the retirement age limit set by Supervisory Board. Therefore, a 

comparison with the partial year period is not meaningful (comparing the 2023 and 2022 financial year).

(7)  James Ryan was appointed to the Management Board as Chief Legal Officer (CLO) as of September 

1, 2023. His compensation for the year ended December 31, 2023 was granted on a pro-rata basis. 

Therefore, a comparison with the prior year is not possible.

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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247

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

F.  CONCLUSION ON  

COMPENSATION SYSTEM  
FOR THE YEAR ENDED  
DECEMBER 31, 2023

The year ended December 31, 2023 was a year in which we continued to 
translate our vision into strong performance and during which our Man-
agement  Board  was  extended  to  include  James  Ryan  as  Chief  Legal 
Officer. Our Supervisory Board expanded by the appointment of Nicola 
Blackwood. She succeeded Christoph Huber, who left the Supervisory 
Board after reaching the retirement age set by the Supervisory Board. 
Ulrich Wandschneider and Michael Motschmann were re-elected as Su-
pervisory Board Members. The term of office of Ulrich Wandschneider, 
Nicola Blackwood and Michael Motschmann will end at the Annual Gen-
eral Meeting in 2027.

To  promote  the  business  strategy  and  the  long-term  development  of 
 BioNTech, we examined our compensation system during the year ended 
December 31, 2023. We engaged an external independent compensation 
consultant to assess the compensation level and structure of our com-
pensation system to ensure that the members of the Management Board 
are retained and to be able to attract new appointments to the Manage-
ment Board, which are in the Company’s long-term interest. The analysis 
showed that our compensation system, which includes targets and caps, 
is in line with market standards and complies with the German Corporate 
Governance Code. The Management Board and the Supervisory Board 
have followed the IDW interpretations for the presentation of compen-
sation in accordance with Sec. 162 of the German Stock Corporation Act 
(AktG), according to which short-term compensation components such 
as fixed compensation and short-term incentives (STI) are presented in 
accordance with interpretation 2 (vesting principle; "Erdienungsprinzip") 
and share-based payments (incl. long-term incentives (LTI) are presented 
in accordance with IDW interpretation 1 (inflow principle; "Zuflussprinzip"). 

Compensation is significantly driven by, and fluctuates, with compensa-
tion derived from our share-based payment arrangements, which are not 
to be seen as cash payments to the Management Board, as the exercise 
was settled by delivering American Depositary Shares, or ADSs, repre-
senting our ordinary shares.  The definition of granted and owed applies 
to the option rights granted under the ESOP 2018 Program, as they were 
exercised and settled in those years ended December 31, 2023 and 2022. 
Even though the entire CEO Grant 2019 became exercisable during the 
year ended December 31, 2023, it was not considered granted and owed, 
as it was not exercised and remains accessible. Those arrangements 
were granted prior to, and alongside with, our IPO. The compensation is 
significantly impacted by our unique and outstanding share price devel-
opment, which incurred between the time the awards were granted and 
the  time  they  were  settled.  Hence,  extraordinary  high  amounts  of  the 
compensation of our members of the Management Board and also a large 
number of select employees were incurred once options were exercised 
and settled mainly during the year ended December 31, 2022 and to a 
lesser extent during the year ended December 31, 2023. With respect to 
the members of the Management Board, we are pleased that they mainly 
retained most of the shares resulting from the after-tax settlement of our 
ESOP 2018 Program and, therefore, they continue to hold an important 
stake in our Company's future. 

During the year ended December 31, 2023, the compensation system for 
our Supervisory Board members was retained from the prior year.

Based on the overall analysis, the Supervisory Board comes to the con-
clusion that the compensation system for the Management Board and 
Supervisory Board, as adopted at the Annual General Meeting, was ap-
plied in all aspects during the year ended December 31, 2023. All agree-
ments with the Management Board contribute to our business strategy.

Given the operational and financial development of BioNTech since the 
launch of the current compensation system, the Compensation, Nom-
inating and Corporate Governance Committee is developing a revised 
compensation system, which the Supervisory board will submit to our 
2024 AGM for approval. The most important changes relate to the LTI for 
the Management Board, whereby Performance Share Units (PSU) will 
be introduced in addition to the existing stock option program. With the 

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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248

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4 COMPENSATION REPORT 

  COMPENSATION REPORT 

  REVIEW OF THE YEAR 
  ENDED DECEMBER 31, 2023

  COMPENSATION OF 
  SUPERVISORY BOARD MEMBERS

  COMPENSATION OF 
  MANAGEMENT BOARD MEMBERS

INFORMATION ON THE 

  RELATIVE DEVELOPMENT OF THE 
  COMPENSATION OF THE MANAGEMENT
  BOARD, THE COMPENSATION OF THE 
  EMPLOYEES AND THE DEVELOPMENT OF 
  THE COMPANY’S EARNINGS

  CONCLUSION ON  COMPENSATION  
  SYSTEM FOR THE YEAR ENDED  
  DECEMBER 31, 2023 

5  FURTHER INFORMATION

introduction of PSUs, the performance hurdle for stock options will be 
also increased. In addition, it is planned that the Management Board will 
be subject to a Share Ownership Guideline, which will require them to hold 
a certain value of BioNTech's shares or ADRs. Furthermore, the remuner-
ation system for the Supervisory Board is also being reviewed in terms 
of  the  appropriateness  of  the  current  level  of  remuneration  given  the 
significant increase in the number and complexity of tasks and increasing 
responsibility for the members of the Supervisory Board and its commit-
tees. It is also planned to present an adjusted remuneration system for the 
Supervisory Board to our 2024 Annual General Meeting for resolution.

Mainz, March 18, 2024

BioNTech SE

For the Management Board

Prof. Ugur Sahin, M.D. 
Chief Executive Officer

Jens Holstein 
Chief Financial Officer

For the Supervisory Board

Helmut Jeggle 
Chair of the Supervisory Board

Prof. Rudolf Staudigl, Ph.D. 
(Chair of Compensation, Nominating and Corpo-
rate Governance Committee)

444 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
249

A CAR-T cell is a patient’s immune cell that  
was equipped with a special antenna called 
receptor, so the immune cell can recognize 
cancer cells better.

FURTHER  
INFORMATION

REPORT 5

INDEPENDENT  
AUDITOR‘S REPORT
REMUNERATION  

INDEPENDENT  
AUDITOR‘S REPORT
CONSOLIDATED  
FINANCIAL  
STATEMENTS

BioNTech | Annual Report 2023BioNTech | Annual Report 2023

250

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4  COMPENSATION REPORT 

5 FURTHER INFORMATION 

INDEPENDENT AUDITOR’S REPORT  

  CONSOLIDATED   
  FINANCIAL STATEMENTS 

INDEPENDENT AUDITOR’S REPORT 

  REMUNERATION REPORT

INDEPENDENT  
AUDITOR’S REPORT

To BioNTech SE

Opinions
We have audited the consolidated financial statements of BioNTech SE, 
Mainz, and its subsidiaries (the Group), which comprise the consolidated 
balance sheet as at 31 December 2023, and the consolidated income 
statement, consolidated statement of other comprehensive income, con-
solidated statement of changes in equity and consolidated statement 
of cash flows for the fiscal year from 1 January to 31 December 2023, 
and notes to the financial statements, including a summary of significant 
accounting policies. In addition, we have audited the combined group 
management report of BioNTech SE for the fiscal year from 1 January  to 
31 December 2023. In accordance with the German legal requirements, 
we  have  not  audited  the  group  statement  on  Group  corporate  gover-
nance declaration pursuant to Secs. 315d HGB [“Handelsgesetzbuch”: 
German Commercial Code] in section 5 of the combined group manage-
ment report. In addition, we have not audited the content of the non-man-
agement report disclosures contained in sections 4.2.3 and 4.2.4 based 
on recommendation A.5 of the German Corporate Governance Code 
(GCGC 2022) and the non-financial report contained in section 7 of the 
combined group management report, which contains non-management 
report disclosures.

In our opinion, on the basis of the knowledge obtained in the audit,

  the  accompanying  consolidated  financial  statements  comply,  in   
all  material  respects,  with  the  IFRSs  as  adopted  by  the  EU,  and  
the additional requirements of German commercial law pursuant to 
Sec. 315e (3) in conjunction with (1) HGB and, in compliance with these 
requirements, give a true and fair view of the assets, liabilities and finan-
cial position of the Group as at 31 December 2023 and of its financial 
performance for the fiscal year from 1 January to 31 December 2023, 
and

  the accompanying group management report as a whole provides 
an appropriate view of the Group’s position. In all material respects, this 
group management report is consistent with the consolidated financial 
statements, complies with German legal requirements and appropri-
ately presents the opportunities and risks of future development. We 
do not express an opinion on the content of the statement on corpo-
rate governance or on the sections 4.2.3, 4.2.4 and 7 of the combined 
management report referred to above.

Pursuant to Sec. 322 (3) Sentence 1 HGB, we declare that our audit has 
not led to any reservations relating to the legal compliance of the consoli-
dated financial statements and of the group management report.

Basis for the opinions
We conducted our audit of the consolidated financial statements and of 
the group management report in accordance with Sec. 317 HGB and in 
compliance with German Generally Accepted Standards for Financial 
Statement Audits promulgated by the Institut der Wirtschaftsprüfer [In-
stitute of Public Auditors in Germany] (IDW). Our responsibilities under 
those requirements and principles are further described in the “Auditor’s 
responsibilities for the audit of the consolidated financial statements and 
of the group management report” section of our auditor’s report. We are 
independent of the Group entities in accordance with the requirements of 
German commercial and professional law, and we have fulfilled our other 
German professional responsibilities in accordance with these require-
ments. We believe that the audit evidence we have obtained is sufficient 
and appropriate to provide a basis for our opinions on the consolidated 
financial statements and on the group management report.

5 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

251

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4  COMPENSATION REPORT 

5 FURTHER INFORMATION 

INDEPENDENT AUDITOR’S REPORT  

  CONSOLIDATED   
  FINANCIAL STATEMENTS 

INDEPENDENT AUDITOR’S REPORT 

  REMUNERATION REPORT

Other information
The Supervisory Board is responsible for the report of the Supervisory 
Board in the “Report of the Supervisory Board” section. The executive 
directors and the Supervisory Board are responsible for the declaration 
pursuant to Sec. 161 AktG [“Aktiengesetz”: German Stock Corporation 
Act] on the German Corporate Governance Code, which is part of the 
Group corporate governance declaration. In all other respects, the exec-
utive directors are responsible for the other information. The other infor-
mation comprises the aforementioned corporate governance declaration 
and the sections 4.2.3, 4.2.4 and 7 of the Group management report. The 
other information also comprises parts to be included in the annual report, 
of which we received a version prior to issuing this auditor’s report, in 
particular:

  Sustainability Report,

  Report of the Supervisory Board,

  Remuneration report,

but not the consolidated financial statements, not the management report 
disclosures whose content is audited and not our auditor’s report thereon.

Furthermore, the other information includes other components intended 
for the annual report which are expected to be made available to us after 
the audit opinion has been issued, in particular:

  the letter from the Executive Board to the shareholders,

  the multi-year overview of business development.

Our opinions on the consolidated financial statements and on the com-
bined group management report do not cover the other information, and 
consequently we do not express an opinion or any other form of assur-
ance conclusion thereon.

In connection with our audit, our responsibility is to read the other infor-
mation and, in so doing, to consider whether the other information

  is materially inconsistent with the consolidated financial statements, 
with the group management report or our knowledge obtained in the 
audit, or

  otherwise appears to be materially misstated.

If, based on the work we have performed, we conclude that there is a ma-
terial misstatement of this other information, we are required to report that 
fact. We have nothing to report in this regard.

Responsibilities of the executive directors and the supervisory board 
for the consolidated financial statements and the group management 
report
The executive directors are responsible for the preparation of the con-
solidated financial statements that comply, in all material respects, with 
IFRSs as adopted by the EU and the additional requirements of German 
commercial  law  pursuant  to  Sec  315e  (3)  in  conjunction  with  (1)  HGB 
and that the consolidated financial statements, in compliance with these 
requirements, give a true and fair view of the assets, liabilities, financial po-
sition and financial performance of the Group. In addition, the executive di-
rectors are responsible for such internal control as they have determined 
necessary to enable the preparation of consolidated financial statements 
that are free from material misstatement, whether due to fraud (i.e., fraud-
ulent financial reporting and misappropriation of assets) or error.

In preparing the consolidated financial statements, the executive direc-
tors are responsible for assessing the Group’s ability to continue as a 
going concern. They also have the responsibility for disclosing, as appli-
cable, matters related to going concern. In addition, they are responsible 
for financial reporting based on the going concern basis of accounting, 
unless there is an intention to liquidate the Group or to cease operations, 
or there is no realistic alternative but to do so.

5 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

252

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4  COMPENSATION REPORT 

5 FURTHER INFORMATION 

INDEPENDENT AUDITOR’S REPORT  

  CONSOLIDATED   
  FINANCIAL STATEMENTS 

INDEPENDENT AUDITOR’S REPORT 

  REMUNERATION REPORT

Furthermore, the executive directors are responsible for the preparation 
of the group management report that, as a whole, provides an appropriate 
view of the Group’s position and is, in all material respects, consistent 
with the consolidated financial statements, complies with German legal 
requirements and appropriately presents the opportunities and risks of 
future development. In addition, the executive directors are responsible 
for such arrangements and measures (systems) as they have considered 
necessary to enable the preparation of a group management report that 
is in accordance with the applicable German legal requirements, and to 
be able to provide sufficient appropriate evidence for the assertions in the 
group management report.

The supervisory board is responsible for overseeing the Group’s financial 
reporting process for the preparation of the consolidated financial state-
ments and of the group management report.

Auditor’s responsibilities for the audit of the consolidated financial 
statements and of the group management report 
Our objectives are to obtain reasonable assurance about whether the 
consolidated financial statements as a whole are free from material mis-
statement, whether due to fraud or error, and whether the group man-
agement report as a whole provides an appropriate view of the Group’s 
position and, in all material respects, is consistent with the consolidated 
financial statements and the knowledge obtained in the audit, complies 
with the German legal requirements and appropriately presents the op-
portunities and risks of future development, as well as to issue an auditor’s 
report that includes our opinions on the consolidated financial statements 
and on the group management report.

Reasonable assurance is a high level of assurance, but is not a guarantee 
that an audit conducted in accordance with Sec. 317 HGB and in compli-
ance with German Generally Accepted Standards for Financial Statement 
Audits promulgated by the Institut der Wirtschaftsprüfer (IDW) will always 
detect a material misstatement. Misstatements can arise from fraud or 
error and are considered material if, individually or in the aggregate, they 
could reasonably be expected to influence the economic decisions of 
users taken on the basis of these consolidated financial statements and 
this group management report.

We exercise professional judgment and maintain professional skepticism 
throughout the audit. We also:

  Identify and assess the risks of material misstatement of the con-
solidated financial statements and of the group management report, 
whether due to fraud or error, design and perform audit procedures 
responsive to those risks, and obtain audit evidence that is sufficient 
and appropriate to provide a basis for our opinions. The risk of not 
detecting a material misstatement resulting from fraud is higher than 
the risk of not detecting a material misstatement resulting from error, 
as fraud may involve collusion, forgery, intentional omissions, misrepre-
sentations, or the override of internal control.

  Obtain  an  understanding  of  internal  control  relevant  to  the  audit 
of  the  consolidated  financial  statements  and  of  arrangements  and 
measures (systems) relevant to the audit of the group management 
report in order to design audit procedures that are appropriate in the 
circumstances, but not for the purpose of expressing an opinion on the 
effectiveness of these systems. 

  Evaluate the appropriateness of accounting policies used by the 
executive directors and the reasonableness of estimates made by the 
executive directors and related disclosures.

  Conclude on the appropriateness of the executive directors’ use 
of the going concern basis of accounting and, based on the audit evi-
dence obtained, whether a material uncertainty exists related to events 
or conditions that may cast significant doubt on the Group’s ability to 
continue as a going concern. If we conclude that a material uncertainty 
exists, we are required to draw attention in the auditor’s report to the 
related disclosures in the consolidated financial statements and in 
the group management report or, if such disclosures are inadequate, 
to modify our respective opinions. Our conclusions are based on the 
audit evidence obtained up to the date of our auditor’s report. However, 
future events or conditions may cause the Group to cease to be able to 
continue as a going concern.

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253

We communicate with those charged with governance regarding, among 
other matters, the planned scope and timing of the audit and significant 
audit findings, including any significant deficiencies in internal control that 
we identify during our audit.

Cologne, 20. March 2024 

EY GmbH & Co. KG
Wirtschaftsprüfungsgesellschaft 

Schlebusch 
Wirtschaftsprüfer 
(German Public Auditor) 

Weigel  
Wirtschaftsprüfer 
(German Public Auditor)

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4  COMPENSATION REPORT 

5 FURTHER INFORMATION 

INDEPENDENT AUDITOR’S REPORT  

  CONSOLIDATED   
  FINANCIAL STATEMENTS 

INDEPENDENT AUDITOR’S REPORT 

  REMUNERATION REPORT

  Evaluate the overall presentation, structure and content of the con-
solidated financial statements, including the disclosures, and whether 
the consolidated financial statements present the underlying transac-
tions and events in a manner that the consolidated financial statements 
give a true and fair view of the assets, liabilities, financial position and 
financial performance of the Group in compliance with IFRSs as adopt-
ed by the EU and the additional requirements of German commercial 
law pursuant to Sec. 315e (3) in conjunction with (1) HGB.

  Obtain sufficient appropriate audit evidence regarding the financial 
information of the entities or business activities within the Group to 
express  opinions  on  the  consolidated  financial  statements  and  on 
the group management report. We are responsible for the direction, 
supervision and performance of the group audit. We remain solely re-
sponsible for our opinions.

  Evaluate the consistency of the group management report with the 
consolidated financial statements, its conformity with law, and the view 
of the Group’s position it provides.

  Perform audit procedures on the prospective information presented 
by the executive directors in the group management report. On the 
basis of sufficient appropriate audit evidence we evaluate, in particular, 
the significant assumptions used by the executive directors as a basis 
for the prospective information, and evaluate the proper derivation of 
the prospective information from these assumptions. We do not ex-
press a separate opinion on the prospective information and on the as-
sumptions used as a basis. There is a substantial unavoidable risk that 
future events will differ materially from the prospective information.

5 
 
 
 
 
 
 
 
 
 
BioNTech | Annual Report 2023

254

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4  COMPENSATION REPORT 

5 FURTHER INFORMATION 

INDEPENDENT AUDITOR’S REPORT  

  CONSOLIDATED   
  FINANCIAL STATEMENTS 

INDEPENDENT AUDITOR’S REPORT 

  REMUNERATION REPORT

REPORT OF THE INDEPENDENT 
AUDITOR ON THE AUDIT OF 
THE REMUNERATION REPORT 
PURSUANT TO SEC. 162 (3) AKTG

To BioNTech SE

Opinion
We  have  audited  the  formal  aspects  of  the  remuneration  report  of 
 BioNTech SE, Mainz, for the fiscal year from 1 January to 31 December 
2023 to determine whether the disclosures required by Sec. 162 (1) and 
(2)  AktG  [“Aktiengesetz”:  German  Stock  Corporation  Act]  have  been 
made therein. In accordance with Sec. 162 (3) AktG, we have not audited 
the content of the remuneration report.  

In our opinion, the disclosures required by Sec. 162 (1) and (2) have been 
made in the accompanying remuneration report in all material respects. 
Our opinion does not cover the content of the remuneration report.

Basis for the opinion
We conducted our audit of the remuneration report in accordance with 
Sec. 162 (3) AktG and in compliance with the IDW Auditing Standard: 
Audit of the Remuneration Report in Accordance with Sec. 162 (3) AktG 
(IDW AuS 870 (09.2023)). Our responsibilities under this provision and 
standard are further described in the “Responsibilities of the auditor” sec-
tion of our report. As an audit firm, we applied the IDW Standard on Quality 
Management: Requirements for Quality Management in the Audit Firm 
(IDW QS 1). We complied with the professional obligations pursuant to the 
WPO [“Wirtschaftsprüferordnung”: German Law Regulating the Profes-
sion of Wirtschaftsprüfer (German Public Auditor)] and the BS WP/vBP 
[“Berufssatzung für Wirtschaftsprüfer/vereidigte Buchprüfer”: Profes-
sional Charter for German Public Accountants/German Sworn Auditors] 
including the requirements regarding independence.

Responsibilities of the management board and supervisory board
The management board and supervisory board are responsible for the 
preparation of the remuneration report and the related disclosures in 
compliance with the requirements of Sec. 162 AktG. In addition, they are 
responsible for such internal control as they determine is necessary to 
enable the preparation of a remuneration report and the related disclo-
sures that are free from material misstatement, whether due to fraud (i.e., 
fraudulent financial reporting and misappropriation of assets) or error.

Responsibilities of the auditor
Our objectives are to obtain reasonable assurance about whether the 
disclosures required by Sec. 162 (1) and (2) AktG are made in the remu-
neration report in all material respects and to express an opinion thereon 
in a report.  

We planned and performed our audit so as to determine the formal com-
pleteness of the remuneration report by comparing the disclosures made 
in the remuneration report with the disclosures required by Sec. 162 (1) 
and (2) AktG. In accordance with Sec. 162 (3) AktG, we have not audited 
the accuracy of the disclosures, the completeness of the individual disclo-
sures or the fair presentation of the remuneration report.  

Consideration of misrepresentations
In connection with our audit, our responsibility is to read the remuneration 
report considering the knowledge obtained in the audit of the financial 
statements and, in doing so, remain alert for indications of whether the re-
muneration report contains misrepresentations in relation to the accuracy 
of the disclosures, the completeness of the individual disclosures or the 
fair presentation of the remuneration report.  

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BioNTech | Annual Report 2023

255

1  MAGAZINE 

2  COMBINED MANAGEMENT  
  REPORT

3  GROUP REPORT 

4  COMPENSATION REPORT 

5 FURTHER INFORMATION 

INDEPENDENT AUDITOR’S REPORT  

  CONSOLIDATED   
  FINANCIAL STATEMENTS 

INDEPENDENT AUDITOR’S REPORT 

  REMUNERATION REPORT

If, based on the work we have performed, we conclude that there is a 
misrepresentation, we are required to report that fact. We have nothing to 
report in this regard.

Cologne, 20. March 2024 

EY GmbH & Co. KG
Wirtschaftsprüfungsgesellschaft 

Schlebusch 
Wirtschaftsprüfer 
(German Public Auditor) 

Weigel  
Wirtschaftsprüfer 
(German Public Auditor)

5