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Biotron Limited

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FY2010 Annual Report · Biotron Limited
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BIOTRON LIMITED   ABN 60 086 399 144

ANNUAL REPORT

2010

CONTENTS

Operating and Financial Review

Statement of Corporate Governance

Directors’ Report

Statement of Comprehensive Income

Statement of Financial Position

Statement of Changes in Equity

Statement of Cash Flows

Notes to the Financial Statements

Directors’ Declaration

Independent Auditor’s Report

Additional Stock Exchange Information

Corporate Directory

2 – 4

5 – 7 

8 – 16

17

18

19

20

21 – 36

37

38 – 39

40 – 41

42

OPERATING AND FINANCIAL REVIEW

Review of Operations

The period under review has seen a continual focus on the clinical 
progression  of  Biotron’s  antiviral  drug  development  program, 
specifically on the clinical development of the Company’s lead 
drug, BIT225, in its HIV and Hepatitis C virus (HCV) programs.

Significant events achieved in this financial year include:

•  Successful conclusion of a Phase Ib/IIa clinical trial of Biotron’s 
lead drug, BIT225, in HCV infected subjects. This marked a 
major milestone for the Company.

•  Finalisation  of  design  of  Phase  IIa  clinical  trial  of  BIT225, 
completion  of  documentation  for  ethics  and  regulatory 
submissions, and submission of documentation to relevant     
authorities for approval for trial.

•  Appointment  of  an  experienced  CRO  (contract  research     
organisation) that   specialises in HIV and HCV clinical trials, 
to  manage  the  clinical  trial  at  sites  in  South  America  and 
Asia.

•  Demonstration  that  BIT225  can  limit  the  spread  of  HIV  in 

cells taken from HIV infected patients.

•  Presentation  of  data  from  the  Company’s  HCV  and  HIV 

programs at   international scientific conferences.

• 

Initiation and successful completion of a $2.1 million capital 
raising via an option issue, which was fully underwritten by 
Bell Potter and Martin Place Securities.

•  A  further  $641,000  was  raised  from  the  early  exercise  of 

options at the end of March 2010.

Clinical Development of BIT225

Biotron has an impressive pipeline of world class clinical programs 
developing new drugs to treat significant viral diseases including 
HCV  and  HIV.  To  date,  Biotron  has  successfully  completed 
two  human  trials  of  its  lead  drug  BIT225  -  an  investigational,         
orally-administered,  novel  antiviral  compound  in  development 
by  Biotron  for  treatment  of  HCV  and  HIV  infections.  These 
trials include a 48 person first-in-human safety study in healthy       
volunteers in late 2007, and more recently a Phase Ib/IIa trial of 
the drug in people infected with HCV, completed in late 2009.

BIT225  represents  a  first-in-class  drug  for  treatment  of  HCV, 
targeting the p7 protein of HCV. It is estimated that in the USA 
alone, some 4 million people have been infected with Hepatitis 
C with 2.7 million suffering from chronic infection. Worldwide, 
170  million  people  are  infected.  HCV  causes  inflammation  of 
the  liver,  which  may  lead  to  fibrosis  and  cirrhosis,  liver  cancer 
and, ultimately, liver failure. Existing drugs which treat HCV have 
limited  effectiveness  and  toxicity  issues,  leaving  a  significant 
need for new therapies.

Biotron’s  Phase  Ib/IIa  trial  was  the  first  study  of  the  drug  in  a 
patient  population.  A  total  of  18  infected  patients,  randomly 
assigned  to  receive  either  one  of  two  doses  of  BIT225,  or 
placebo, taking the drug twice daily for 7 days. The study was 
successfully completed, with analysis indicating that within that 
trial  design  the  drug  appeared  to  be  safe  and  well  tolerated, 
and most importantly, showed that BIT225 can reduce levels of 
the HCV in a number of treated patients receiving the highest 
dose  of  drug,  compared  to  those  receiving  placebo.  This  was 
an  important  and  exciting  result,  and  supports  the  on-going                  
development of the Company’s drug.

The  next  stage  of  development  of  BIT225  is  to  test  it  in 
combination with the currently approved HCV drugs in patients 
infected with HCV, which, given that antiviral drugs cannot be 
used on their own to treat chronic infections due to development 
of  drug    resistance,  is  how  BIT225  will  most  likely  to  be  used 
in a clinical setting. These existing drugs (interferon alpha and 
ribavirin) are often associated with severe side effects, and have 
limited  benefit  in  a  large  percentage  of  patients.    BIT225  has 
been shown to be highly synergistic with these drugs in preclinical 
laboratory testing, which means that greater reductions in virus 
levels can be achieved using smaller quantities of the drugs in 
combination than if they were used individually.

During  the  first  half  of  2010,  Biotron’s  focus  has  been  on             
finalising the design of this combination trial, and in preparing 
the  detailed  documentation  required  by  ethics  and  regulatory 
authorities.  The  approval  process  is  a  multistep  process, 
involving  ethics  committees  and  review  boards  overseeing  the 
trial sites, and government authorities which are responsible for 
issuing permits to import drug and final approvals to start the 
trial, progressing to the next stage of testing of BIT225 against 
the Hepatitis C virus. This trial will test the drug over a longer 
treatment  period  in  combination  with  the  approved  drugs  in 
patients  infected  with  HCV  genotype  1,  the  most  common 
variant of the virus in the Western world.  Not only is genotype 
1 the most common type of HCV, but it is also the form that is 
most resistant to current approved drugs, with less than 50% of 
treated patients responding to treatment.

Biotron’s application documentation has successfully passed the 
first step in the ethics approval process, and is now progressing 
through the next stage of approvals. We anticipate the trial will 
conclude before the end of 2010.

The  worldwide  market  for  HCV  treatment  is  currently  almost 
US$3.0  billion,  but  is  estimated  that  this  market  will  expand 
to  over  US$10.0  billion  as  safe,  effective  therapies  enter  the 
market.  The  pharmaceutical  industry  is  particularly  interested 
in  new  drugs  that  specifically  target  the  replication  cycle  of 
the  Hepatitis  C  virus,  and  there  is  considerable  interest  in  the 
outcomes of Biotron’s Phase IIa combination trial.

Biotron Annual Report 2010

2

OPERATING AND FINANCIAL REVIEW

BIT225  also  works  against  HIV,  the  virus  that  causes  AIDS. 
BIT225  specifically  targets  HIV  in  reservoir  cells  and  represents 
an opportunity to attack HIV at its source in the body. Current 
HIV therapies have  little or no effect on HIV in the underlying 
reservoir of infected cells where the virus hides from the immune 
system. Late in 2009, Biotron scientists presented a paper at an 
international conference, reporting that BIT225 is able to limit 
the spread of virus in cells isolated from HIV-infected patients.

The  Company  proposes  to  progress  BIT225  into  a  proof-of-
concept Phase Ib/IIa trial in HIV infected patients when funding 
permits.  

These  trials  in  HCV  and  HIV  patients  are  critical  steps  in  the 
Company’s development. Demonstration that BIT225 can attack 
these  viruses  in  patients  will  be  a  major  advance  in  terms  of 
Company and technology valuations. The Company is focused 
on  achieving  a  successful  outcome,  and  has  been  updating 
potential  commercial  partners  on  progress  on  a  regular  basis 
while  progressing  its  clinical  trial  program.  First-in-class  drugs 
are  often  very  attractive  to  pharmaceutical  companies  as  they 
can provide an opportunity to secure the largest market share, 
in  contrast  with  ‘me-too’  next  generation  of  existing  classes 
of  drug.    However,  this  benefit  is  often  linked  to  the  need  to 
provide evidence that the new class, with a new mode of action, 
has clinical benefit.

The  HCV  Phase  IIa  combination  trial  has  been  specifically 
designed  with  the  aim  of  providing  the  information  that 
potential  partners  are  likely  to  require  in  order  to  form  a 
partnership  with  an  international  pharmaceutical  company  for 
continued development. 

Other Viral Programs

The  Company  has  an  impressive  portfolio  of  clinical  and           
preclinical  antiviral  programs  developing  drugs  targeting  HCV, 
HIV, Dengue virus and Influenza virus.  At present, focus is on 
development of the HCV and HIV programs into trials in infected 
patient populations, and additional resources will be committed 
to these additional programs once the more advanced programs 
have been successfully commercialised or as resources become 
available. Right now, the clearer commercial path for Biotron is 
firstly focusing on its Hepatitis C program, and secondly, exploiting 
BIT225 to reduce the viral reservoirs in HIV infected patients. 

The level of interest by the international community in Biotron’s 
antiviral programs was reflected by the selection of Biotron to 
participate  in  prestigious  international  scientific  conferences 
over  the  last  12  months.  In  December  2009,  Biotron  was 
selected to present at the biannual HepDART conference in the 
USA as well as the International Workshop on HIV Persistence.  
In May 2010, Biotron attended the annual international biotech 

industry partnering conference, BIO2010, in Chicago USA, and 
presented to an investor showcase preceding that conference.

Patents

Biotron  is  focused  on  progressing  patents  related  to  its 
antiviral programs through the international patenting process. 
The  Company  recognises  that  the  key  to  establishment  of 
partnerships  is  the  expansion  and  continued  strengthening  of 
Biotron’s  intellectual  property  (IP)  portfolio.  Strong,  defensible, 
international  patents  are  essential  to  attract  partners  and  to 
ensure  a  competitive  advantage  for  the  Company’s  products 
in the marketplace. Biotron continues to build a strong wall of 
patents around its IP to maximise the value of the technologies 
and to ensure its competitive position.

A summary of Biotron’s patent portfolio is set out below:

TITLE

STATUS

WO0021538
Method of modulatingion channel 
functional activity 
Priority - 12 October 1998

WO9813514 
Method of determining ion channel 
activity of a substance
Priority - 27 September 1996

WO04112687  
Antiviral compounds and methods 
Priority - 26 June 2003 Granted in India

WO6135978 
Antiviral compounds and methods 
Priority - 24 June 2005

WO2009/018609  
Hepatitis C antiviral compounds and 
methods 
Priority - 3 August 2007

New Director

Granted in Australia, Canada, China, 
New Zealand, and USA 
Under examination elsewhere

Granted in Australia, Japan, 
Europe and USA 
Under examination elsewhere

New Zealand, Singapore and 
South Africa 
Under examination elsewhere

Granted in South Africa 
Waiting for or 
under examination elsewhere

Waiting for examination in all 
jurisdictions

This past year has seen the Company welcome a new director 
to Biotron’s board with credentials we believe will be important 
to  further  Biotron’s  commercial  success.  Dr  Denis  Wade  has 
been  a  director  of  several  private  and  public  companies  in 
the  pharmaceutical  sector,  including  Heartware  Limited  and 
HeartWare International Inc. Among other stellar appointments, 
he has served as a managing director and chairman of Johnson 
and Johnson Research Pty Ltd, and is a former chairman of the 
Clinical  Pharmacology  Section  of  the  International  Union  of 
Pharmacology.

3

Biotron Annual Report 2010

            
Capital Raising

In December 2009, the Company initiated a capital raising via an option issue, which was fully underwritten by Bell Potter and Martin 
Place Securities. The issue closed, over-subscribed, in early January 2010, raising $2.1 million. A number of shareholders elected for 
early exercise of these options at the end of March 2010, raising an additional $641,000 in funds. 

The Directors would like to thank all those shareholders who supported the Company by participating in this capital raising. 

On behalf of the Board we would like to thank the dedicated Biotron staff for their commitment and efforts during the year. Biotron 
is poised to achieve the outcome that we have all been working towards – demonstration that its antiviral drug development program 
can produce new, novel drugs which can attack virus infections in humans, resulting in significant clinical benefit to patients, and 
generating major financial benefits to our shareholders.  

We look forward to the next year with confidence. 

Michael J. Hoy 

Chairman 

Michelle Miller

Managing Director

Biotron Annual Report 2010

4

  
  
 
 
   
 
 
 
 
 
 
 
 
 
 
STATEMENT OF CORPORATE GOVERNANCE

This  statement  outlines  the  main  Corporate  Governance 
practices that were in place throughout the financial year, which 
comply  with  the  Australian  Stock  Exchange  (‘ASX’)  Corporate 
Governance Council recommendations, unless otherwise stated.

Board of Directors

The  board  of  directors  is  responsible  for  the  overall  corporate 
governance  of  the  Company  including  its  strategic  direction, 
setting  remuneration,  establishing  goals  for  management  and 
monitoring  the  achievement  of  these  goals  and  ensuring  the 
integrity  of  internal  control  and  management  information 
systems.    It  is  also  responsible  for  approving  and  monitoring 
financial and other reporting.

The composition of the board has been determined on the basis 
of providing the Company with the benefit of a broad range of 
technical, administrative and financial skills, combined with an 
appropriate level of experience at a senior corporate level. The 
names and further information regarding the skills, experience, 
qualifications and relevant expertise of the directors are set out 
in the Directors’ Report. The board is composed of a minimum 
of three directors.

The composition of the board is monitored constantly to ensure 
that it provides the Company with the appropriate levels of both 
expertise  and  experience.  The  board  comprises  a  majority  of 
independent, non-executive directors including the Chairperson. 
The independence of directors is based on their capacity to put 
the best interests of the Company and its shareholders ahead of 
all other interests.

When a board vacancy exists, through whatever cause, or where 
it is considered that the board would benefit from the services 
of  a  new  director  with  particular  skills,  the  board  identifies  a 
panel of candidates with appropriate expertise and experience. 
A selection procedure is then completed and the board appoints 
the most suitable candidate who must stand for election at the 
next general meeting of shareholders.

Directors, other than the Managing Director, are subject to re-
election by the shareholders at least every three years.

Having regard to the current membership of the board and the 
size, organisational complexity and scope of operations of the 
entity,  a  Nomination  Committee,  a  Remuneration  Committee 
and an Audit Committee have not been established.

Each  director  has  the  right  to  seek  independent  professional 
advice  at  the  Company’s  expense.    Prior  approval  of  the 
Chairman  is  required,  but  such  approval  is  not  unreasonably 
withheld. A copy of the advice received by the director is made 
available to all other members of the board.

In the event that a potential conflict of interest may arise, involved 
directors  must  withdraw  from  all  deliberations  concerning  the 
matter.

Remuneration

The  remuneration  of  the  directors  is  determined  by  the  board 
as  a  whole,  with  the  director  to  whom  a  particular  decision 
relates being absent from the meeting during the time that the 
remuneration level is discussed and decided upon.

For details on the amount of remuneration and any amount of 
equity based executive remuneration payment for each director, 
refer  to  the  Key  Management  Personnel  note  to  the  financial 
statements  and  the  Remuneration  Report  in  the  Directors’ 
Report.

Internal Controls

The  board  of  directors  acknowledges  that  it  is  responsible  for 
the  overall  internal  control  framework,  but  recognises  that  no 
cost effective internal control system will preclude all errors and 
irregularities.  The  system  of  internal  control  adopted  by  the 
Company seeks to provide an appropriate division of responsibility 
and  careful  selection  and  training  of  personnel  relative  to  the 
level of activities and size of the Company.

The  full  board  takes  responsibility  for  reviewing  financial 
reporting procedures, internal controls and the performance of 
the financial management. Selected internal control mechanisms 
employed to support the business include:

• 

Investment  appraisal  –  the  Company  has  documented 
guidelines for capital expenditure and investment appraisals. 
These 
review 
include  annual  budgets,  expenditure 
procedures and appropriate levels of authority.

•  Business  planning,  budgeting  and 

reporting  –  a 
comprehensive business planning process includes evaluation 
of  strategies,  objectives,  and  risks  resulting  in  an  annual 
budget approved by the board. Monthly actual performance 
is reported against budget and revised forecasts for the year 
are prepared regularly.

•  Quality and integrity of employees – there are clearly defined 
accountabilities, performance measures, and reinforcement 
of values and ethics by management.

The  CEO  and  CFO  state  in  writing  to  the  board  that  the 
Company’s  financial  statements  present  a  true  and  fair  view, 
in  all  material  respects,  of  the  Company’s  financial  condition 
and  operational  results  and  are  in  accordance  with  relevant 
accounting standards.

5

Biotron Annual Report 2010

External Auditors

Board  nominees  review  the  performance  of  the  external 
auditors and meet with them during the half yearly review and 
annual audit to discuss any issues that have arisen with respect 
to  accounting  policies,  any  significant  operational  issues  and 
the  level  of  proposed  audit  fees.  The  auditor  is  requested  to 
attend the Annual General Meeting and be available to answer 
shareholder questions about the conduct of the audit and the 
preparation and content of the auditor’s report.

KPMG,  the  Company’s  auditors,  were  appointed  on  20 
November 2001.

Ethical Standards

All directors, managers and employees are expected to act with 
the utmost integrity and objectivity, endeavouring at all times to 
enhance the performance and reputation of the Company. Every 
employee has direct access to a director to whom they may refer 
any ethical issues that may arise from their employment.

Directors, officers and employees are permitted to trade in the 
Company’s  securities  only  in  accordance  with  the  provisions 
of  the  Corporations  Act  and  ASX  Listing  Rules.  The  directors 
are under an obligation to report any dealings by them in the 
Company’s securities.

The Role of Shareholders

The  board  ensures  that  the  shareholders  are  informed  of  all 
major  developments  affecting  the  Company  by  the  following 
means:

•  Distribution  of  the  annual  report  is  made  available  to  all 
shareholders  containing  relevant  information  about  the 
operations  of  the  Company  during  the  year  in  addition  to 
disclosures required by the Corporations Act 2001.

•  Lodgement  of  quarterly  reports  with  the  ASX  which  show 
summarised financial information for the quarter. Copies of 
these reports are available to shareholders on request.

summarised  and  audit 

•  Lodgement  of  the  half  yearly  report  with  the  ASX  which 
reviewed  financial 
contains 
information.  Copies  of  half  yearly  financial  statements 
prepared  in  accordance  with  the  Corporations  Act  are 
available to any shareholder on request.

•  Lodgement of the annual report with the ASX which contains 
full  audited  financial  information  prepared  in  accordance 
with the Corporations Act. Distribution of the annual report 
is made available to all shareholders.

•  Announcements  to  the  ASX  concerning  any  significant 
development  in  the  Company’s  operations,  financing  and 
administration. All announcements are immediately available 
to the general public. 

•  Disclosure  of  all  major  announcements  to  the  ASX  on  the 

Company’s website.

•  The Annual General Meeting is the main opportunity for the 
shareholders to hear the Managing Director and Chairman 
provide  updates  on  the  Company’s  performance,  ask 
questions  of  the  board  and  to  express  views  and  vote  on 
various matters of business on the agenda.

The shareholders are responsible for voting on the appointment 
of directors.

Risk Management

Due  to  the  size  of  the  Company,  the  number  of  officers  and 
employees and the nature of the Company’s business, a formal 
risk  management  policy  and  internal  compliance  and  control 
system has not been implemented. The CEO and CFO declare, 
in  writing,  to  the  board  that  the  system  of  risk  management 
and  internal  compliance  and  control  which  implements  the 
policies adopted by the board has been assessed and found to 
be operating efficiently and effectively in all material respects.

Each director reviews the business risks affecting his particular 
area  of  expertise  annually  and  reports  to  the  board.  The 
board then determines the appropriate actions to eliminate or 
minimise  the  identified  business  risks.  The  full  board  oversees 
the  establishment,  implementation  and  ongoing  review  of 
the  Company’s  risk  management  and  internal  control  system. 
The  internal  control  system  covers  financial,  operational  and 
compliance risks.

Recommendations made by external auditors and other external 
advisers  are  investigated  by  the  board  and,  where  necessary, 
appropriate action is taken to ensure that the Company has the 
internal control environment to manage the key risks identified.  
Ways  of  enhancing  existing  risk  management  strategies, 
including  segregation  of  duties,  employment  and  training  of 
suitably qualified and experienced personnel are investigated by 
the board.

Biotron Annual Report 2010

6

STATEMENT OF CORPORATE GOVERNANCE

Performance  Evaluation  of  the  Board  and 
Key Executives

Due  to  the  size  of  the  Company,  the  number  of  officers  and 
employees and the nature of the Company’s business, the board 
has adopted an informal and continuous performance evaluation 
process of the directors and key executives. The Company has 
not  established  formal  performance  review  measures  for  the 
board  or  key  executives  nor  has  it  established  a  nomination 
committee.

Share Trading Policy

The  board  restricts  directors,  executives  and  employees  from 
acting on material information until it has been released to the 
market.    Share  trading  by  directors,  executives  or  employees 
is  not  permitted  at  any  time  whilst  in  the  possession  of  price 
sensitive  information  not  already  available  to  the  market.    In 
addition, the Corporations Act prohibits the purchase or sale of 
securities whilst a person is in possession of inside information.

Restricted  Persons  can  only  trade  the  Company’s  securities 
during specific trading windows.  All periods outside the specific 
trading  windows  are  closed  periods  where  Restricted  Persons 
are prohibited from trading in the Company’s securities unless 
in special circumstances and with the approval of the Chairman.

Trading windows are the 60 days from the first trading day after 
each of the following:

• 

• 

• 

the day half year results are announced;

the day full year results are announced; and

the day of the Annual General Meeting.

7

Biotron Annual Report 2010

DIRECTORS’ REPORT

The  directors  present  their  report  together  with  the  financial 
report of Biotron Limited (‘the Company’) for the year ended 30 
June 2010 and the auditor’s report thereon.

Committee  of  the  Department  of  Industry,  Science  and 
Resources.    He  is  currently  a  director  of  Dynamic  Hearing  and 
TGR BioSciences.

Dr Hirshorn was appointed as a director on 16 March 2000.

Directors 

The names and particulars of the directors of the Company at 
any time during or since the end of the financial year are:

Mr Bruce Hundertmark

Independent and Non-Executive Director

Mr Michael J. Hoy

Independent and Non-Executive Chairman

Mr Hoy has more than 30 years’ corporate experience in Australia, 
the United Kingdom, USA and Asia.  He is Chairman of CityPrint 
Holdings Pty Limited, Chairman of Tellesso Technologies Limited 
and a former director of John Fairfax Holdings Limited and FXF 
Trust. 

He  has  been  a  director  since  7  February  2000  and  Chairman 
since 16 March 2000.

Mr Hundertmark is an independent businessman and company 
director  with  a  wide  range  of  experience  in  diverse  business 
operations.  He has specialised in recent years in high technology 
based  company  start-up  operations  and  in  promoting  the 
formation  of  venture  capital  companies 
including  News 
Datacom  Research  Limited  in  Israel,  News  Datacom  Limited  in 
Hong Kong and both PT Indo Bio Products and PT Indo Bio Fuels 
in Indonesia.

He has been a director of numerous private and publicly listed 
companies including News International PLC, Sky Television PLC, 
Prudential  Cornhill  Insurance  Limited,  Harris  Scarfe  Limited, 
Bernkastel  Wines  Limited,  Codan  Limited,  Samic  Limited  and 
Investment & Merchant Finance Corporation Limited.

Dr Michelle Miller, BSc, MSc, PhD, GCertAppFin (Finsia)

Mr Hundertmark was appointed as a director on 16 March 2000.

Managing Director

Dr Miller has worked for over 20 years in the bioscience industry, 
with  extensive  experience  in  managing  commercial  bioscience 
research.    She  completed  her  PhD  in  the  Faculty  of  Medicine 
at  Sydney  University  investigating  molecular  models  of  cancer 
development.    Her  experience  includes  a  number  of  years  at 
Johnson  and  Johnson  developing  anti-HIV  gene  therapeutics 
through preclinical research to clinical trials.  She has experience 
in early-stage start-ups from time spent as Investment Manager 
with a specialist bioscience venture capital fund.

She was appointed as Managing Director on 21 June 2002.

Dr Michael S. Hirshorn, MBA, MB, BS

Independent and Non-Executive Director

Dr  Hirshorn  has  30  years  experience  in  founding,  building, 
managing  and  investing  in  technology  companies.    He  played 
a  major  role  in  all  commercial  aspects  of  Cochlear  Limited’s 
development, was a founding director of Resmed Inc., and Chief 
Executive Marketing for Polartechnics Limited.

He  has  over  eight  years  of  private  equity  experience,  raising 
funds,  investing  and  developing  companies.    He  has  served 
on  numerous  government  advisory  committees,  including  the 
Start IT and T Committee, the Start Grants Biological Sciences 

Dr Denis N. Wade

Non-Executive Director 

Dr  Denis  Wade  has  been  involved  for  over  40  years  with  the 
development  of  research-based  pharmaceuticals  and  medical 
devices in both industry and academia.  He has been a director 
of several private and public companies in the Health-care sector, 
including  Heartware  Limited  and  subsequently  HeartWare 
International  Inc.,  since  December  2004.    He  was  a  Director 
and Chairman of Gene Shears Pty Limited and, from 1987 until 
his  retirement  in  2002,  Dr.  Wade  was  Managing  Director  and 
Chairman  of  Johnson  &  Johnson  Research  Pty  Ltd,  a  research 
and  development  company  of  Johnson  and  Johnson  Inc.      He 
was  also  a  member  of  the  J&J  Corporate  Office  of  Science 
and Technology,   Prior to that, Dr. Wade was the Foundation 
Professor  of  Clinical  Pharmacology  at  the  University  of  New 
South Wales and served as a member of a number of State and 
Federal  bodies  related  to  the  drug  industry,  including  the  P3 
Committee.  

He  is  a  former  Chairman  of  the  Australian  Academy  National 
Committee  for  Pharmacology,  the  Australasian  Society  for 
Clinical  and  Experimental  Pharmacology  and  Toxicology  and  a 
former  Chairman  of  the  Clinical  Pharmacology  Section  of  the 
International Union of Pharmacology.

Biotron Annual Report 2010

8

 
 
DIRECTORS’ REPORT

Dr  Wade  holds  a  First  Class  Honours  degree  in  Medicine  and 
Science  from  the  University  of  Sydney  and  a  Doctorate  of 
Philosophy  from  the  University  of  Oxford.    He  was  awarded 
an  Honorary  Doctorate  of  Science  by  the  University  of  New 
South Wales and is a Fellow of the Royal Australasian College 
of  Physicians  and  of  the  Australian  Academy  of  Technological 
Sciences and Engineering.   In 1999 he was made a Member of 
the Order of Australia. 

Dr Wade was appointed as a Director on 30 April 2010.

Mr Peter G. Scott

Non-Executive Director

Mr  Scott  is  a  founding  director  of  Biotron  Limited  with  more 
than 30 years of commercial and entrepreneurial experience in 
Australia.

He  is  a  director  of  Scott’s  Acorn  Pty  Ltd  and  was  formerly 
Chairman  and  Managing  Director  of  Scottcom  Pty  Ltd  and 
Managing Director of ICAM Pty Ltd, audio visual and multimedia 
companies.

Mr Peter Scott resigned on 1 April 2010.

Directors’ Meetings

Peter J. Nightingale

Company Secretary

Mr Nightingale graduated with a Bachelor of Economics degree 
from the University of Sydney and is a member of the Institute 
of  Chartered  Accountants  in  Australia.    He  has  worked  as  a 
chartered accountant in both Australia and the USA.  

As  a  director  or  company  secretary  Mr  Nightingale  has,  for 
the  past  22  years,  been  responsible  for  the  financial  control, 
administration,  secretarial  and  in-house  legal  functions  of  a 
number of private and public listed companies in Australia, the 
USA and Europe including Pangea Resources Limited, Timberline 
Inc.,  Perseverance  Corporation  Limited,  Valdora 
Minerals 
Minerals  N.L.,  Bolnisi  Gold  NL  and  Palmarejo  Silver  and  Gold 
Corporation.  Mr  Nightingale  is  currently  a  director  of  Augur 
Resources  Ltd,  Callabonna  Uranium  Limited,  Cockatoo  Coal 
Limited and Planet Gas Limited.

Mr Nightingale has been company secretary since 23 February 
1999.

The number of directors’ meetings held and number of meetings attended by each of the directors of the Company, while they were 
a director, during the year are:

Director

No. of Eligible Meetings to Attend

No. of Meetings Attended

Directors’ Meetings

Michael J. Hoy

Michelle Miller

Michael S. Hirshorn

Bruce Hundertmark

Denis N. Wade

Peter G. Scott

6

6

6

6

1

5

6

6

6

5

1

5

9

Biotron Annual Report 2010

 
Directors’ Interests

At the date of this report, the beneficial interests of each director of the Company in the issued share capital of the Company and 
options, each exercisable to acquire one fully paid ordinary share of the Company are:

Fully Paid Ordinary 
Shares

Michael J. Hoy

1,408,214

Michelle Miller

Michael S. Hirshorn

Bruce Hundertmark

Denis N. Wade*

  -

  -

  -

130,000

  -

475,000

Options

500,000
1,408,214

500,000

500,000

500,000

200,000

200,000

162,500

Option Terms
(Exercise Price and Term)

$0.35 at any time up to 30 September 2010
$0.10 at any time up to 30 December 2011

$0.35 at any time up to 30 September 2010

$0.40 at any time from 30 September 2006 up to 30 September 2010

$0.45 at any time from 30 September 2007 up to 30 September 2010

$0.35 at any time up to 30 September 2010

$0.35 at any time up to 30 September 2010

$0.20 at any time up to 30 March 2012

* Dr Denis N. Wade held 475,000 shares and 162,500 options at the time of becoming a director.

Option Holdings

The movement during the reporting period in the number of options over ordinary shares in the Company held directly, indirectly or 
beneficially, by each specified director and executive, including their personally-related entities, is as follows:

Option holdings - 2010

Directors

Michael J. Hoy

Michelle Miller

Michael S. Hirshorn

Bruce Hundertmark

Denis N. Wade*

Peter G. Scott**

Executives

Peter J. Nightingale

Held at
1 July 2009

Purchased

Expired

Held at
30 June 2010

Vested and 
Exercisable
at 30 June 2010

500,000

1,500,000

200,000

200,000

-

-

1,408,214

-

-

-

-

500,000

200,000

2,287,785

-

-

-

-

-

-

-

1,908,214

1,500,000

200,000

200,000

162,500

-

1,908,214

1,500,000

200,000

200,000

162,500

-

2,487,785

2,487,785

* Dr Denis N. Wade held 162,500 options at the time of becoming a director.
** Mr Peter G. Scott held 500,000 options when he resigned from office on 1 April 2010.

Biotron Annual Report 2010

10

DIRECTORS’ REPORT

Option holdings - 2009

Directors

Michael J. Hoy

Michelle Miller

Michael S. Hirshorn

Bruce Hundertmark

Peter G. Scott

Executives

Peter J. Nightingale

Held at
1 July 2008

Purchased

Expired

Held at
30 June 2009

Vested and 
Exercisable
at 30 June 2009

500,000

1,500,000

200,000

200,000

-

200,000

-

-

-

-

-

-

-

-

-

-

-

-

500,000

1,500,000

200,000

200,000

-

500,000

1,500,000

200,000

200,000

-

200,000

200,000

Remuneration Report - Audited

The  policy  of  remuneration  of  directors  and  senior  executives 
is  to  ensure  the  remuneration  package  properly  reflects  the 
person’s  duties  and  responsibilities,  and  that  remuneration  is 
competitive  in  attracting,  retaining  and  motivating  people  of 
the  highest  quality.    The  board  is  responsible  for  reviewing  its 
own performance. The non-executive directors are responsible 
for  evaluating  the  performance  of  the  executive  directors 
who,  in  turn,  evaluate  the  performance  of  all  other  senior 
executives.  The  evaluation  process  is  intended  to  assess  the 
Company’s business performance, whether long term strategic 
objectives are being achieved and the achievement of individual 
performance objectives.

Remuneration  generally  comprises  salary  and  superannuation. 
Longer  term  incentives  are  able  to  be  provided  through  the 
Company’s  Incentive  Option  Plan  which  acts  to  align  the 
directors  and  senior  executives’  actions  with  the  interests  of 
the shareholders. The remuneration disclosed below represents 
the cost to the Company for the services provided under these 
arrangements.

11

Biotron Annual Report 2010

No directors or senior executives receive performance related remuneration. Options issued in prior periods as remuneration were 
subject to service conditions due to the nature of the Company’s operations.

Details of director and senior executive remuneration and the nature and amount of each major element of the remuneration of each 
director and senior executive of the Company are:

Directors Non-executive
Michael J. Hoy (Chairman)

Michael S. Hirshorn

Bruce Hundertmark

Peter G. Scott

Denis N. Wade

Executive
Michelle Miller (Managing Director)

Executives

Peter J. Nightingale (Company Secretary)

Year

2010

2009

2010

2009

2010

2009

2010

2009

2010

2009

2010

2009

2010

2009

Primary Salary 
and Fees 
$

Post-Employment 
Superannuation Benefits  
$

55,046

55,046

27,523

27,523

27,523

27,523

20,642

5,000

4,587

-

219,230

200,000

75,000

75,000

4,954

4,954

2,477

2,477

2,477

2,477

1,858

25,000

-

-

19,731

18,000

-

-

Total
$

60,000

60,000

30,000

30,000

30,000

30,000

22,500

30,000

4,587

-

238,961

218,000

75,000

75,000

Options granted as compensation - Audited

Details of options that were granted as compensation to each key management person: 

Director

Grant Date

Number of 
Options Granted

Fair Value 
at Grant Date

Option Terms
(Exercise Price and Term)

Michelle Miller

14 October 2005

Michelle Miller

14 October 2005

Michelle Miller

14 October 2005

500,000

500,000

500,000

$24,016

$21,114

$18,701

$0.35 at any time up to 
30 September 2010

$0.40 at any time from 
30 September 2006 up to 30 September 2010

$0.45 at any time from
30 September 2007 up to 30 September 2010

The number of options that had vested as at 30 June 2010 is 1,500,000 (2009 – 1,500,000). There were no options that vested 
during the year ended 30 June 2010, no options were granted during or subsequent to year end and no options lapsed during the 
year.

Biotron Annual Report 2010

12

DIRECTORS’ REPORT

The fair value of the options at grant date was determined based on the Black-Scholes formula. The model inputs of the options 
issued, were the Company’s share price of $0.17 at the grant date, a volatility factor of 50% based on historic share price performance 
and a risk free interest rate of 5.25% based on the 10 year government bond rate.

Consequences of Performance on Shareholder Wealth - Audited

In considering the Company’s performance and benefits for shareholders wealth, the board have regard to the following indices in 
respect of the current financial year and the previous four financial years.

Net loss attributable to equity holders of 
the Company

Dividends paid

Change in share price

2010

2009

$1,872,244

$1,776,099

2008

$1,882,093

-

-

-

(0.02) cents

0.0 cents

(9.0) cents

2007

$3,234,004

-

4.5 cents

2006

$2,198,973

-

7.0 cents

The overall level of key management personnel’s compensation is assessed on the basis of market conditions, status of the Company’s 
projects, and financial resources of the Company.

Service Contracts - Audited

There are no service contracts for the key management personnel.

Non-executive Directors - Audited

Total compensation for all non-executive directors is determined by the board based on market conditions.

Options

At the date of this report, unissued ordinary shares of the Company under option are:

Number of Options

Exercise Price

5,450,000

750,000

500,000

108,119,266

* 6,418,049

$0.35

$0.40

$0.45

$0.10

$0.20

Expiry Date

30 September 2010

30 September 2010

30 September 2010

30 December 2011

30 March 2012

The options do not entitle the holder to participate in any share issue of the Company or any other body corporate.

* During the year, the Company issued 6,418,049 ordinary shares as a result of the exercise of $0.10 options.  There is no amount 
unpaid on the shares issued.  A further 6,418,049 $0.20 ‘Piggy Back’ options were issued for no consideration as a result of the early 
exercise of these options. Refer Note 11.

Number of Shares

6,418,049

Amount Paid on Each Share

$0.10

13

Biotron Annual Report 2010

Principal Activities

The principal activities of the Company during the financial year 
were the funding and management of intermediate and applied 
biotechnology research and development projects.

Financial Result and Review of Operations

The operating loss of the Company for the financial year after 
income tax was $1,872,244 (2009 loss - $1,776,099).

A review of the Company’s operations for the year is set out in 
the Operating and Financial Review.

In the opinion of the directors, it would prejudice the interests 
of  the  Company  to  provide  additional  information,  except  as 
reported in this Annual Report, relating to likely developments 
in the operations of the Company.

Indemnification of Officers and Auditors

During or since the end of the financial year, the Company has 
not indemnified or made a relevant agreement to indemnify an 
officer or auditor of the Company against a liability incurred by 
such an officer or auditor. In addition, the Company has not paid 
or  agreed  to  pay,  a  premium  in  respect  of  a  contract  insuring 
against a liability incurred by an officer or auditor.

Impact  of  Legislation  and  Other  External 
Requirements

Non-audit Services

During  the  year  KPMG,  the  Company’s  auditor,  performed  no 
other services in addition to their statutory duties.

The  board  has  considered  the  non-audit  services  provided 
during  the  prior  year  by  the  auditor  and  is  satisfied  that  the 
provision of those non-audit services during the prior year by the 
auditor is compatible with, and did not compromise, the auditor 
independence  requirements  of  the  Corporations  Act  2001  for 
the following reasons:

•  all  non-audit  services  were  subject  to  the  corporate 
governance procedures adopted by the Company and have 
been reviewed by the board to ensure they do not impact 
the integrity and objectivity of the auditor; and

• 

the  non-audit  services  provided  did  not  undermine  the 
general principles relating to auditor independence as set out 
in APES 110 Code of Ethics for Professional Accountants, as 
they did not involve reviewing or auditing the auditor’s own 
work, acting in a management or decision making capacity 
for the Company, acting as an advocate for the Company or 
jointly sharing risks and rewards.

There  were  no  changes  in  environmental  or  other  legislative 
requirements  during  the  year  that  have  significantly  impacted 
the results or operations of the Company.

Dividends

The  directors  recommend  that  no  dividend  be  paid  by  the 
Company. No dividend has been paid or declared since the end 
of the previous financial year.

State of Affairs

In the opinion of the directors, there were no significant changes 
in the state of affairs of the Company that occurred during the 
financial year under review.

Environmental Regulation

The  Company’s  operations  are  not  subject  to  significant 
environmental  regulations  under  Commonwealth  or  State 
legislation in relation to its research projects.

Events Subsequent to Balance Date

There  has  not  arisen  in  the  interval  between  the  end  of  the 
financial year and the date of this report any item, transaction 
or event of a material and unusual nature likely, in the opinion 
of  the  directors  of  the  Company,  to  affect  significantly  the 
operations of the Company, the results of those operations, or 
the state of affairs of the Company, in future financial years.

Likely Developments

During the year ended 30 June 2010, the Company continued 
to fund and manage its research and development projects. The 
success  of  these  research  projects,  which  cannot  be  assessed 
on  the  same  fundamentals  as  trading  and  manufacturing 
enterprises, will determine future likely developments.

Biotron Annual Report 2010

14

DIRECTORS’ REPORT

A copy of the auditors’ independence declaration as required under Section 307C of the Corporations Act 2001 is included in the 
Directors’ Report.

Details of the amounts paid and accrued to the auditor of the Company, KPMG, and its related practices for audit and non-audit 
services provided during the year are set out below.

Statutory audit 

- Audit and review of financial reports 

Services other than statutory audit 

 2010 
 $ 

34,375 

 2009
  $

26,240

- Grant audit 

         - 

              1,750

Lead Auditor’s Independence Declaration

The Lead Auditor’s Independence Declaration is set out on page 16 and forms part of the Directors’ Report for the year ended 30 
June 2010.

This report has been signed in accordance with a resolution of the directors and is dated 30 August 2010:

Michael J. Hoy 

Chairman 

Michelle Miller

Managing Director

15

Biotron Annual Report 2010

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Lead Auditor’s Independence Declaration under Section 307C of the Corporations Act 2001

To the Directors of Biotron Limited:

I declare that, to the best of my knowledge and belief, in relation to the audit for the financial year ended 30 June 2010, there have 
been:

(i)  no contraventions of the auditor independence requirements as set out in the Corporations Act 2001 in relation to the audit, and

(ii)  no contraventions of any applicable code of professional conduct in relation to the audit.

KPMG 

W.E. Austin

Partner
Brisbane 30 August 2010

Biotron Annual Report 2010

16

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
STATEMENT OF COMPREHENSIVE INCOME
FOR THE YEAR ENDED 30 JUNE 2010

Other income

Administration and consultants’ expenses

Depreciation

Employee and director expenses

Direct research and development expenses

Rent and outgoings expenses

Legal expenses

Other expenses from ordinary activities

Operating loss before financing income

Interest income

Net financing income

Loss before tax

Income tax expense

Loss for the year

Other comprehensive income

Total comprehensive loss for the year

Basic loss per share attributable to ordinary equity shareholders

Diluted loss per share attributable to ordinary equity shareholders

Notes

2

3

3

5

4

4

2010

$

-

(196,335)

(23,122)

(380,171)

(965,313)

(58,233)

-

(292,076)

2009

$

5,000

(172,000)

(47,731)

(360,746)

(980,294)

(51,351)

(6,675)

(221,277)

(1,915,250)

(1,835,074)

43,006

43,006

58,975

58,975

(1,872,244)

(1,776,099)

-

-

(1,872,244)

(1,776,099)

-

-

(1,872,244)

(1,776,099)

(1.61) cents

(1.61) cents

(1.67) cents

(1.67) cents

The above statement of comprehensive income should be read in conjunction with the accompanying notes

17

Biotron Annual Report 2010

STATEMENT OF FINANCIAL POSITION
AT 30 JUNE 2010

Current assets

Cash and cash equivalents

Trade and other receivables

Other

Total current assets

Non-current assets

Plant and equipment

Total non-current assets

Total assets

Current liabilities

Trade and other payables

Employee entitlements

Total current liabilities

Total liabilities

Net assets

Equity

Issued capital

Reserves

Accumulated losses

Total equity

Notes

6

7

8

9

10

2010

$

1,780,567

9,471

23,577

1,813,615

44,230

44,230

2009

$

950,581

27,520

18,385

996,486

67,352

67,352

1,857,845

1,063,838

62,212

78,075

140,287

140,287

1,717,558

136,397

85,935

222,332

222,332

841,506

11

20,750,759

19,920,593

2,277,738

359,608

(21,310,939)

(19,438,695)

1,717,558

841,506

The above statement of financial position should be read in conjunction with accompanying notes

Biotron Annual Report 2010

18

STATEMENT OF CHANGES IN EQUITY
FOR THE YEAR ENDED 30 JUNE 2010

Attributable to equity holders of the 
Company

Notes

Share 
Capital 

Option 
Premium 
Reserve 

Retained 
Losses 

Total

           $

             $

             $

           $

Balance at 1 July 2008

19,146,365

359,608

(17,662,596)

1,843,377

Total comprehensive income for the year

Loss for the year

Other comprehensive income

-

-

-

-

(1,776,099)

(1,776,099)

-

-

Total comprehensive loss for the year

19,146,365

359,608

(19,438,695)

67,278

Transactions with owners, recorded directly in 
equity

Contribution by and distribution to owners

Ordinary shares issued

Cost of the share issue

807,500

(33,272)

-

-

-

-

807,500

(33,272)

Balance at 30 June 2009

11

19,920,593

359,608

(19,438,695)

841,506

Balance at 1 July 2009

19,920,593

359,608

(19,438,695)

841,506

Total comprehensive income for the year

Loss for the year

Other comprehensive income

Total comprehensive loss for the year

Transaction with owners, recorded directly in equity

Contribution by and distribution to owners

Ordinary shares/options issued

Cost of the option issue

Share based payment transaction

Exercise of options

-

-

-

-

-

-

(1,872,244)

(1,872,244)

-

-

(1,872,244)

(1,872,244)

641,805

2,290,746

-

(244,255)

60,000

-

128,361

(128,361)

-

-

-

-

2,932,551

(244,255)

60,000

-

Balance at 30 June 2010

11

20,750,759

2,277,738

(21,310,939)

1,717,558

The statement of changes in equity is to be read in conjunction with the accompanying notes

19

Biotron Annual Report 2010

STATEMENT OF CASH FLOWS
FOR THE YEAR ENDED 30 JUNE 2010

Cash flows from operating activities

Cash receipts in the course of operations

Payments for research and development

Cash payments in the course of operations

Cash used in operations

Interest received

Notes

2010

$

2009

$

-

3,910

(1,138,088)

(1,081,839)

(765,239)

(883,264)

(1,903,327)

(1,961,193)

45,017

68,950

Net cash used in operating activities

12

(1,858,310)

(1,892,243)

Cash flows from investing activities

Proceeds on sale of plant and equipment

Payments for plant and equipment

Net cash from investing activities

Cash flows from financing activities

Proceeds from issue of shares and options

Cost of issue of shares and options

Net cash from financing activities

Net increase/(decrease) in cash and cash equivalents held

Cash and cash equivalents at the beginning of the financial year

-

-

-

2,932,551

(244,255)

2,688,296

829,986

950,581

Cash and cash equivalents at the end of the financial year

12

1,780,567

The above statement of cash flows should be read in conjunction with the accompanying notes

5,000

-

5,000

807,500

(33,272)

774,228

(1,113,015)

2,063,596

950,581

Biotron Annual Report 2010

20

NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2010

1. REPORTING ENTITY

Biotron  Limited  (the  ‘Company’)  is  a  company  domiciled  in 
Australia.

Basis of preparation
Statement of compliance

(‘AASBs’) 

(including  Australian 

The financial report is a general purpose financial report which 
has  been  prepared  in  accordance  with  Australian  Accounting 
Standards 
Interpretations) 
adopted  by  the  Australian  Accounting  Standards  Board 
(‘AASB’)  and  the  Corporations  Act  2001.  The  financial  report 
of  the  Company  also  complies  with  International  Financial 
Reporting Standards (IFRSs) and interpretations adopted by the 
International Accounting Standards Board (IASB). 

The financial report was authorised for issue by the directors on 
30 August 2010.

Basis of measurement

The  financial  statements  have  been  prepared  on  the  historical 
cost basis.

Functional and presentation currency

These  financial  statements  are  presented  in  Australian  dollars, 
which is the Company’s functional currency.

Use of estimates and judgements

The  preparation  of  financial  statements  requires  management 
to make judgements, estimates and assumptions that affect the 
application of accounting policies and the reported amounts of 
assets, liabilities, income and expenses.  Actual results may differ 
from these estimates. 

Estimates  and  underlying  assumptions  are  reviewed  on  an 
ongoing basis.  Revisions to accounting estimates are recognised 
in the period in which the estimate is revised and in any future 
periods affected.

In  particular,  information  about  significant  areas  of  estimation 
uncertainty  and  critical  judgements  in  applying  accounting 
policies  that  have  the  most  significant  effect  on  the  amounts 
recognised  in  the  financial  statements  are  described  in  the 
following notes.- Note 1 Going Concern.

Going concern

The financial report has been prepared on a going concern basis 
which contemplates the realisation of assets and settlement of 
liabilities in the ordinary course of business.

The  Company  has  incurred  a  trading  loss  of  $1,872,244  in 
the  year  ended  30  June  2010  and  has  accumulated  losses  of 
$21,310,939  as  at  30  June  2010.  The  Company  has  cash  on 

hand of $1,780,587 at 30 June 2010 and used $1,853,310 of 
cash  in  operations  for  the  year  then  ended.  These  conditions 
give rise to a material uncertainty that may cast significant doubt 
upon the Company’s ability to continue as a going concern.  The 
ongoing operation of the Company is dependent on:

• 

• 

the  Company raising additional funding from  shareholders 
or other parties; and/or

the  Company  reducing  expenditure  in  line  with  available 
funding.

The directors have prepared cash flow projections that support 
the  ability  of  the  Company  to  continue  as  a  going  concern.  
These  cash  flow  projections  assume  the  Company  obtains 
sufficient additional funding from shareholders or other parties.  
If such funding is not achieved, the Company plans to reduce 
expenditures significantly.

In  the  event  that  the  Company  does  not  obtain  additional 
funding  and/or  reduce  expenditure  in  line  with  available 
funding, it may not be able to continue its operations as a going 
concern and therefore may not be able to realise its assets and 
extinguish its liabilities in the ordinary course of operations and 
at the amounts stated in the financial statements.

Changes in accounting policies
Commencing  on  1  July  2009,  the  Company  changed  its 
accounting policies in the following areas:

•  presentation of financial statements; and

•  operating segments.

Significant accounting policies
The  accounting  policies  set  out  below  have  been  applied 
consistently to all periods presented in these financial statements, 
and have been applied consistently by the Company, except as 
explained  in  the  notes  which  address  changes  in  accounting 
policies.

Cash and cash equivalents
Cash  and  cash  equivalents  comprise  cash  balances  and  call 
deposits.

Trade and other receivables
Trade  and  other  receivables  are  stated  at  their  amortised  cost 
less impairment losses.

21

Biotron Annual Report 2010

Property, plant and equipment
Property plant and equipment are stated at their historical cost 
less  accumulated  depreciation  and  accumulated  impairment 
losses.    Depreciation  is  recognised  in  profit  or  loss  using  the 
reducing balance method from the date of acquisition at rates 
between 13% and 40% per annum.

Research and development
Grants

Where a grant is received relating to research and development 
costs  that  have  been  expensed,  the  grant  is  recognised  as 
revenue when there is reasonable assurance it will be received.

Costs

Expenditure  on  research  activities,  undertaken  with  the 
prospect of gaining new scientific or technical knowledge and 
understanding, is recognised in profit and loss when incurred.

Development activities involve a plan or design for the production 
of  new  or  substantially  improved  products  and  processes.  
Development  expenditure  is  capitalised  only  if  development 
costs  can  be  measured  reliably,  the  product  or  process  is 
technically and commercially feasible, future economic benefits 
are  probable,  and  the  Company  intends  to  and  has  sufficient 
resources to complete development and to use or sell the asset.  
The  expenditure  capitalised  includes  the  cost  of  materials, 
direct  labour  and  overhead  costs  that  are  directly  attributable 
to preparing the asset for its intended use.  Other development 
expenditure is recognised in profit or loss when incurred. 

Capitalised  development  expenditure  is  measured  at  cost  less 
accumulated amortisation and accumulated impairment losses.

Trade and other payables
Trade and other payables are stated at their amortised cost, are 
non-interest bearing and are normally settled within 60 days.

Employee entitlements
Wages, salaries, annual leave and sick leave

Liabilities for employee entitlements for wages, salaries, annual 
leave  and  sick  leave  represent  present  obligations  resulting 
from employees’ services provided to reporting date, calculated 
at  undiscounted  amounts  based  on  remuneration  wages  and 
salary  rates  that  the  company  expect  to  pay  as  at  reporting 
date including related on-costs, such as workers compensation 
insurance and superannuation.

Long service leave

Liabilities for employee entitlements for long service leave is the 
amount of future benefit that employees have earned in return 
for  their  service  in  the  current  and  prior  periods  plus  related 

on-costs,  that  benefit  is  discounted  to  determine  its  present 
value.

Share capital
Ordinary shares

Ordinary shares are classified as equity. Incremental costs directly 
attributable to the issue of ordinary shares and share options are 
recognised  as  a  deduction  from  equity,  net  of  any  tax  effects.  
Dividends on ordinary shares are recognised as a liability in the 
period in which they are declared.

Taxation
Income tax

Income tax on the profit or loss for the year comprises current 
and  deferred  tax.    Income  tax  is  recognised  in  the  income 
statement except to the extent that it relates to items recognised 
directly in equity, in which case it is recognised in equity.

Current tax is the expected tax payable on the taxable income 
for the year, using tax rates enacted or substantially enacted at 
the  balance  sheet  date,  and  any  adjustment  to  tax  payable  in 
respect of previous years.

Deferred  tax  is  provided  using  the  balance  sheet  method, 
providing  for  temporary  differences  between  the  carrying 
amounts of assets and liabilities for financial reporting purposes 
and  the  amounts  used  for  taxation  purposes.    The  initial 
recognition of assets or liabilities that affect neither accounting 
nor  taxable  profit,  and  differences  relating  to  investments  in 
subsidiaries to the extent that they will probably not reverse in 
the  foreseeable  future  are  temporary  differences  and  are  not 
provided for.  The amount of deferred tax provided is based on 
the expected manner of realisation or settlement of the carrying 
amount  of  assets  and  liabilities,  using  tax  rates  enacted  or 
substantively enacted at the balance sheet date.

A  deferred  tax  asset  is  recognised  only  to  the  extent  that  it  is 
probable  that  future  taxable  profits  will  be  available  against 
which the asset can be utilised.  Deferred tax assets are reduced 
to the extent that it is no longer probable that the related tax 
benefit will be realised.

Goods and services tax

Revenue, expenses and assets are recognised net of the amount 
of goods and services tax (‘GST’), except where the amount of 
GST incurred is not recoverable from the taxation authority.  In 
these circumstances, the GST is recognised as part of the cost of 
acquisition of the asset or as part of the expense.

Receivables  and  payables  are  stated  with  the  amount  of  GST 
included.  The net amount of GST recoverable from, or payable 
to,  the  ATO  is  included  as  a  current  asset  or  liability  in  the 
balance sheet.

Biotron Annual Report 2010

22

NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2010

Cash  flows  are  included  in  the  statement  of  cash  flows  on  a 
gross  basis.    The  GST  components  of  cash  flows  arising  from 
investing and financing activities which are recoverable from, or 
payable to, the ATO are classified as operating cash flows.

Revenue recognition
Finance income

Interest  revenue  is  recognised  as  it  accrues  using  the  effective 
interest rate method.

Earnings per share
The Company presents basic and diluted earnings per share (EPS) 
data for its ordinary shares.  Basic EPS is calculated by dividing 
the  profit  or  loss  attributable  to  ordinary  shareholders  of  the 
Company by the weighted average number of ordinary shares 
outstanding  during  the  period.    Diluted  EPS  is  determined  by 
adjusting the profit or loss attributable to ordinary shareholders 
and the weighted average number of ordinary shares outstanding 
for  the  effects  of  all  dilutive  potential  ordinary  shares,  which 
comprise share options granted to employees.

Incentive option plan
The Incentive Option Plan allows the Company’s employees or 
directors, or individuals whom the Plan Committee determine to 
be employees for the purposes of the Plan, with the opportunity 
to acquire options over unissued shares in the Company.  The fair 
value of options granted is measured at grant date and spread 
as an expense over the period during which the employees or 
directors  become  unconditionally  entitled  to  the  options.    The 
fair  value  of  the  options  granted  is  measured  using  Black-
Scholes formula, taking into account the terms and conditions 
upon which the options were granted.  The amount recognised 
as an expense is adjusted to reflect the actual number of options 
that vest except where forfeiture is only due to share prices not 
achieving the threshold for vesting.

Impairment
Financial assets

A financial asset is assessed at each reporting date to determine 
whether  there  is  any  objective  evidence  that  it  is  impaired.    A 
financial  asset  is  considered  to  be  impaired  if  any  objective 
evidence indicates that one or more events have had a negative 
effect on the estimated future cash flows of that asset.

An  impairment  loss  in  respect  of  a  financial  asset  measured 
at  amortised  cost  is  calculated  as  the  difference  between  its 
carrying amount, and the present value of the estimated future 
cash flows discounted at the original effective interest rate.  An 
impairment loss in respect of an available-for-sale financial asset 
is calculated by reference to its fair value.

All  impairment  losses  are  recognised  in  profit  or  loss.    Any 
cumulative loss in respect of an available-for-sale financial asset 
recognised previously in equity is transferred to profit and loss.

An  impairment  loss  is  reversed  if  the  reversal  can  be  related 
objectively to an event occurring after the impairment loss was 
recognised.    For  financial  assets  measured  at  amortised  cost 
and  available-for-sale  financial  assets  that  are  debt  securities, 
the  reversal  is  recognised  in  profit  or  loss.    For  available-for-
sale  financial  assets  that  are  equity  securities  the  reversal  is 
recognised directly in equity.

Non-financial assets

The carrying amounts of the Company’s non-financial assets are 
reviewed at each reporting date to determine whether there is 
any indication of impairment.  If any such indication exists then 
the asset’s recoverable amount is estimated.

The recoverable amount of an asset or cash-generating unit is 
the greater of its value in use and its fair value less costs to sell.  
In  assessing  value  in  use,  the  estimated  future  cash  flows  are 
discounted to their present value using a pre-tax discount rate 
that  reflects  current  market  assessments  of  the  time  value  of 
money and the risks specific to the asset.

An impairment loss is recognised if the carrying amount of an 
asset or its cash-generating unit exceeds its recoverable amount.  
Impairment losses are recognised in profit or loss.

An  impairment  loss  in  respect  of  goodwill  is  not  reversed.    In 
respect  of  other  assets  impairment  losses  recognised  in  prior 
periods are assessed at each reporting date for any indications 
that the loss has decreased or no longer exists.  An impairment 
loss  is  reversed  if  there  has  been  a  change  in  the  estimates 
used  to  determine  the  recoverable  amount.    An  impairment 
loss  is  reversed  only  to  the  extent  that  the  asset’s  carrying 
amount does not exceed the carrying amount that would have 
been  determined,  net  of  depreciation  or  amortisation,  if  no 
impairment had been recognised.

Determination of fair values
A number of the Company’s accounting policies and disclosures 
require  the  determination  of  fair  value,  for  both  financial 
and  non-financial  assets  and  liabilities.    Fair  values  have  been 
determined  for  measurement  and/or  disclosure  purposes 
based  on  the  following  methods.    Where  applicable,  further 
information  about  the  assumptions  made  in  determining  fair 
values is disclosed in the notes specific to that asset or liability.

Trade and other receivables

The fair value of trade and other receivables is estimated as the 
present value of future cash flows, discounted at the market rate 
of interest at the reporting date.

23

Biotron Annual Report 2010

Share-based payment transactions

The fair value of employee share options is measured using the 
Black-Scholes formula.  Measurement inputs include share price 
on measurement date, exercise price of the instrument, expected 
volatility (based on weighted average historic volatility adjusted 
for  changes  expected  due  to  publicly  available  information), 
weighted  average  expected  life  of  the  instruments  (based  on 
historical  experience  and  general  option  holder  behaviour), 
expected  dividends,  and  the  risk-free  interest  rate  (based  on 
government  bonds).    Service  and  non-market  performance 
conditions  attached  to  the  transactions  are  not  taken  into 
account  in  determining  fair  value.    Share-based  payment 
arrangements in which the Company receives goods or services 
as  consideration  for  its  own  equity  instruments  are  accounted 
for as equity-settled share-based payment transactions. 

Non-derivative financial liabilities

Fair  value,  which  is  determined  for  disclosure  purposes,  is 
calculated  based  on  the  present  value  of  future  principal  and 
interest cash flows, discounted at the market rate of interest at 
the reporting date.

Presentation of financial statements
The Company applies revised AASB 101 Presentation of Financial 
Statements  (2007),  which  became  effective  as  of  1  January 
2009.    As  a  result,  the  Company  presents  in  the  consolidated 
statement  of  changes  in  equity  all  owners  changes  in  equity, 
whereas all non-owners changes in equity are presented in the 
consolidated statement of comprehensive income.

Comparative information has been re-presented so that it also 
is in conformity with the revised standard. Since the changes in 
accounting policy only impacts presentation aspects, there is no 
impact on earnings per share.

Segment reporting
Determination and presentation of operating segments

As  of  1  July  2009  the  Company  determines  and  presents 
operating  segments  based  on  the  information  that  internally 
is provided to the CEO, who is the Company’s chief operating 
decision maker. This change in accounting policy is due to the 
adoption of AASB 8 Operating Segments.  Previously, operating 
segments  were  determined  and  presented  in  accordance  with 
AASB  114  Segment  Reporting.    The  new  accounting  policy  in 
respect of segment operating disclosures is presented as follows.

An  operating  segment  is  a  component  of  the  Company  that 
engages in business activities from which it may earn revenues 
and incur expenses, including revenues and expenses that relate 
to transactions with any of the Company’s other components.  
All operating segments’ operating results are regularly reviewed 

by the Company’s CEO to make decisions about resources to be 
allocated  to  the  segment  and  assess  its  performance,  and  for 
which discrete financial information is available.

Segment results that are reported to the CEO include items directly 
attributable to a segment as well as those that can be allocated 
on  a  reasonable  basis.  Unallocated  items  comprise  mainly  of 
corporate assets (primarily the Company’s headquarters), head 
office expenses, and income tax assets and liabilities.

Segment capital expenditure is the total cost incurred during the 
period to acquire property, plant and equipment, and intangible 
assets other than goodwill.

Since the change in accounting policy only impacts presentation 
and disclosure aspects, there is no impact on earnings per share.

New standards and interpretations not yet 
adopted
The  following  standards,  amendments  to  standards  and 
interpretations have been identified as those which may impact 
the entity in the period of initial application.  They are available 
for early adoption at 30 June 2010, but have not been applied 
in preparing this financial report.

•  AASB 9 Financial Instruments includes requirements for the 
classification and measurement of financial assets resulting 
from the first part of Phase 1 of the project to replace AASB 
139  Financial  Instruments:  Recognition  and  Measurement.  
AASB 9 will become mandatory for the Company’s 30 June 
2014  financial  statements.    Retrospective  application  is 
generally required, although there are exceptions, particularly 
if the entity adopts the standard for the year ended 30 June 
2012 or earlier.  The Company has not yet determined the 
potential effect of the standard.

•  AASB  124  Related  Party  Disclosures  (revised  December 
2009)  simplifies  and  clarifies  the  intended  meaning  of  the 
definition of a related party and provides a partial exemption 
from  the  disclosure  requirements  for  government-related 
entities. The amendments, which will become mandatory for 
the Company’s 30 June 2012 financial statements, are not 
expected to have any impact on the financial statements.

•  AASB 2009-5 further amendments to Australian Accounting 
Standards  arising  from  the  Annual  Improvements  Process 
affect  various  AASBs  resulting  in  minor  changes  for 
presentation,  disclosure,  recognition  and  measurement 
purposes.    The  amendments,  which  become  mandatory 
for  the  Company’s  30  June  2011  financial  statements,  are 
not  expected  to  have  a  significant  impact  on  the  financial 
statements.

Biotron Annual Report 2010

24

NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2010

•  AASB  2009-10  Amendments  to  Australian  Accounting 
Standards  -  Classification  of  Rights  Issue  [AASB  132] 
(October  2010)  clarify  that  rights,  options  or  warrants  to 
acquire a fixed number of an entity’s own equity instruments 
for  a  fixed  amount  in  any  currency  are  equity  instruments 
if  the  entity  offers  the  rights,  options  or  warrants  pro-rata 
to  all  existing  owners  of  the  same  class  of  its  own  non-
derivative  equity  instruments.    The  amendments,  which 
will  become  mandatory  for  the  Company’s  30  June  2011 
financial  statements,  are  not  expected  to  have  any  impact 
on the financial statements.

• 

IFRIC  19  Extinguishing  Financial  Liabilities  with  Equity 
Instruments addresses the accounting by an entity when the 
terms of a financial liability are renegotiated and result in the 
entity issuing equity instruments to a creditor of the entity 
to  extinguish  all  or  part  of  the  financial  liability.    IFRIC  19 
will  become  mandatory  for  the  Company’s  30  June  2011 
financial statements, with retrospective application required.  
The Company has not yet determined the potential effect of 
the interpretation.

•  AASB 2010-3 Further amendments to Australian Accounting 
Standards  arising  from  the  Annual  Improvements  Process 
affect  various  AASBs  resulting  in  minor  changes  for 
presentation,  disclosure,  recognition  and  measurement 
purposes.  The  amendments,  which  become  mandatory 
for  the  Company’s  30  June  2011  financial  statements,  are 
not  expected  to  have  a  significant  impact  on  the  financial 
statements. 

•  AASB 2010-4 Further amendments to Australian Accounting 
Standards  arising  from  the  Annual  Improvements  Process 
affect  various  AASBs  resulting  in  minor  changes  for 
presentation,  disclosure,  recognition  and  measurement 
purposes.  The  amendments,  which  become  mandatory 
for  the  Company’s  30  June  2012  financial  statements,  are 
not  expected  to  have  a  significant  impact  on  the  financial 
statements.

25

Biotron Annual Report 2010

2. OTHER INCOME
Gain on sale of fixed assets

Total

3. LOSS FROM OPERATING ACTIVITIES
Loss from ordinary activities has been arrived at after charging the following items:

Auditors’ remuneration paid to KPMG

- Audit and review of financial reports

- Other services

Depreciation

- Office equipment

- Plant and equipment

Direct research and development expenditure 
expensed as incurred

Provision for employee entitlements

2010
$

-

-

34,375

-

14,995

8,127

965,313

(7,860)

2009
$

5,000

5,000

26,240

1,750

24,831

22,900

980,294

(20,383)

4. LOSS PER SHARE
The calculation of basic loss per share at 30 June 2010 was based on the loss attributable to ordinary shareholders of $1,872,244 
(2009 - $1,776,099) and a weighted average number of ordinary shares outstanding during the financial year ended 30 June 2010 of 
116,088,866 (2009 - 106,600,586), calculated as follows:

Net loss for the year

1,872,244

1,776,099

Issued ordinary shares at 1 July

Effect of shares issued on 14 April 2009

Effect of shares issued on 8 April 2010

Effect of shares issued on 28 May 2010

            2010

            2009

Number

114,537,315

-

1,477,030

74,521

Number

104,443,565

2,157,021

-

-

Weighted average number of ordinary shares

116,088,866

106,600,586

Options disclosed in the Issued Capital Note 11 are potential ordinary shares, but are not included in the calculation of diluted loss per 
share as they are not dilutive.

Biotron Annual Report 2010

26

NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2010

5. INCOME TAX EXPENSE
Numerical reconciliation between tax expense and pre-tax net profit

Loss before tax - continuing operations

(1,872,244)

(1,776,099)

Income tax using the domestic corporation tax rate of 30%

(561,673)

(532,830)

2010
$

2009
$

Increase in income tax expense due to:

 - Adjustments not resulting in temporary differences

 - Unrecognised temporary differences

 - Effect of tax losses not recognised

Income tax expense current and deferred

Deferred tax assets have not been recognised in respect of the following items:

Deductible temporary differences (net)

Tax losses

Net

295

(42,527)

603,905

-

114,386

7,431,227

7,545,613

2,371

(24,045)

554,504

-

85,004

6,618,540

6,703,544

The deductible temporary differences and tax losses do not expire under the current tax legislation. Deferred tax assets have not been 
recognised in respect of these items because it is not probable that future taxable profit will be available against which the Company 
can utilise the benefits of the deferred tax asset.

6. RECEIVABLES
Current

Other debtors

GST receivable

7. OTHER
Current prepayments

Security deposits

1,875

7,596

9,471

8,447

15,130

23,577

2,011

25,509

27,520

3,255

15,130

18,385

27

Biotron Annual Report 2010

8. PLANT AND EQUIPMENT
Office equipment - at cost 

Accumulated depreciation

Plant and equipment - at cost

Accumulated depreciation

Total plant and equipment - net book value

Reconciliations

Reconciliations of the carrying amounts for each class of plant and equipment are set out below:

Office equipment

Balance at 1 July

Depreciation

Carrying amount at the end of the financial year

Plant and equipment

Balance at 1 July

Depreciation

Carrying amount at the end of the financial year

Total carrying amount at the end of the financial year

9. TRADE AND OTHER PAYABLES
Current

Creditors

Accruals

10. EMPLOYEE ENTITLEMENTS
Current

Employee annual leave provision

Long service leave provision

Number of employees at the end of the financial year

Biotron Annual Report 2010

2010
$

157,439

(133,610)

23,829

594,490

(574,089)

20,401

44,230

38,824

(14,995)

23,829

28,528

(8,127)

20,401

44,230

32,324

29,888

62,212

34,047

44,028

78,075

4

2009
$

157,439

(118,615)

38,824

594,490

(565,962)

28,528

67,352

63,655

(24,831)

38,824

51,428

(22,900)

28,528

67,352

34,897

101,500

136,397

46,722

39,213

85,935

4

28

NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2010

11. ISSUED CAPITAL
Issued and paid up capital

121,755,364 (2009 - 114,537,315) fully paid ordinary shares

20,750,759

19,920,593

2010

$

2009

$

Fully paid ordinary shares

Balance at the beginning of the financial year

Issue of shares

Share base payment transaction

Exercise of options

Costs of issue

Balance at the end of financial year

19,920,593

641,805

60,000

128,361

-

19,146,365

807,500

-

-

(33,272)

20,750,759

19,920,593

Holders  of  ordinary  shares  are  entitled  to  receive  dividends  as 
declared  from  time  to  time  and  are  entitled  to  one  vote  per 
share at shareholders’ meetings.  In the event of winding up of 
the Company, ordinary shareholders rank after creditors and are 
fully entitled to any proceeds of liquidation.

During  the  year  ended  30  June  2009,  the  Company  issued 
10,093,750  ordinary  shares  through  a  Share  Purchase  Plan 
and  placement  for  cash  totalling  $807,500.    Total  issue  costs 
of $33,272 were recognised as a reduction of the proceeds of 
issue of these shares.

During  the  year  ended  30  June  2010,  the  Company  issued 
114,537,315 options at $0.02 each (2009 nil).  Total issue costs 
of  $244,255  were  recognised  as  a  reduction  of  the  proceeds 
of  the  issue  of  these  options.    Also  during  the  year  ended  30 
June  2010,  a  further  6,418,049  options  were  issued  for  no 
consideration as a result of the early exercise of these options.

The following options, which were issued during the year ended 
30 June 2010 for cash consideration or as a ‘piggyback option’ 
upon the early exercise of an existing option, were on issue at 
30 June 2010:

•  108,119,266 options, each exercisable at 10 cents to acquire 
one fully paid ordinary share at any time up to 30 December 
2011.

•  6,418,049 options, each exercisable at 20 cents to acquire 
one  fully  paid  ordinary  share  at  any  time  up  to  30  March 
2012.

The  following  options,  were  issued  during  the  year  ended  30 
June 2008 and were on issue at 30 June 2010:

•  1,000,000 options, each exercisable at 35 cents to acquire 
one fully paid ordinary share at any time up to 30 September 
2010.

During  the  year  ended  30  June  2010,  the  Company  issued 
6,418,049  ordinary  shares  through  the  exercise  of  options  for 
cash totalling $641,805.

•  4,450,000 options, each exercisable at 35 cents to acquire 
one fully paid ordinary share at any time up to 30 September 
2010 (of which certain options contained service conditions).

During  the  year  ended  30  June  2010,  the  Company  issued 
800,000  shares  for  $60,000  in  consideration  for  the  provision 
of market research services.  The shares issued were valued by 
reference to the closing share price on the date of issue.

•  750,000 options, each exercisable at 40 cents to acquire one 
fully  paid  ordinary  share  at  any  time  up  to  30  September 
2010 (of which certain options contained service conditions).

•  500,000 options, each exercisable at 45 cents to acquire one 
fully  paid  ordinary  share  at  any  time  up  to  30  September 
2010 (of which certain options contained service conditions).

29

Biotron Annual Report 2010

The fair value of the options at each grant date was determined based on the Black-Scholes formula.  The model inputs for those 
options issued during the year ended 30 June 2008, were the Company’s share price of $0.22 at the grant date, a volatility factor of 
89.4% based on historic share price performance and a risk free interest rate of 7.25% based on the 10 year government bond rate.

Total  expense  arising  from  share  based  payment  transactions  recognised  during  the  year  ended  30  June  2010  was  $60,000  
(2009 – $nil).

During the year ended 30 June 2010, no options lapsed (2009 – nil).

The weighted average exercise price of options at year end was $0.12 (2009 – $0.363).

12. STATEMENT OF CASH FLOWS
Reconciliation of cash flows from operating activities

Loss for the period

(1,872,244)

(1,776,099)

2010

$

2009

$

Adjustments for:

Depreciation of plant and equipment

Provisions

Share based payment

Gain on sale of plant and equipment

Changes in assets and liabilities

Decrease in receivables

(Increase)/decrease in prepayments

(Decrease) in payables

Decrease in other assets

23,122

(7,860)

60,000

-

18,049

(5,192)

(74,185)

-

47,731

(20,383)

(5,000)

31,963

686

(181,230)

10,089

Net cash used in operating activities

(1,858,310)

(1,892,243)

Reconciliation of cash

For the purposes of the Statement of Cash Flows, cash includes cash on hand and at bank and cash on deposit net of bank overdrafts 
and excluding security deposits. Cash at the end of the financial year as shown in the Statement of Cash Flows is reconciled to the 
related items in the Statement of Financial Position as follows:

Cash and cash equivalents in the statement of cash flows

1,780,567

950,581

Biotron Annual Report 2010

30

NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2010

13. KEY MANAGEMENT PERSONNEL  
      DISCLOSURES

The  policy  of  remuneration  of  directors  and  senior  executives 
is  to  ensure  the  remuneration  package  properly  reflects  the 
person’s  duties  and  responsibilities,  and  that  remuneration  is 
competitive  in  attracting,  retaining  and  motivating  people  of 
the  highest  quality.  The  board  is  responsible  for  reviewing  its 
own performance. The non-executive directors are responsible 
for  evaluating  the  performance  of  the  executive  directors 
who,  in  turn,  evaluate  the  performance  of  all  other  senior 
executives.  The  evaluation  process  is  intended  to  assess  the 
Company’s business performance, whether long term strategic 
objectives are being achieved and the achievement of individual 
performance objectives.

Remuneration  generally  comprises  salary  and  superannuation. 
Longer  term  incentives  are  able  to  be  provided  through  the 
Company’s  Incentive  Option  Plan  which  acts  to  align  the 
directors  and  senior  executives’  actions  with  the  interests  of 
the shareholders. The remuneration disclosed below represents 
the cost to the Company for the services provided under these 
arrangements.

No  directors  or  senior  executives  receive  performance  related 
remuneration. No bonuses were paid during the year.

Details  of  director  and  senior  executive  remuneration  and  the 
nature and amount of each major element of the remuneration 
of each director and senior executive of the Company are:

Directors

Non-executive

Michael J. Hoy 

(Chairman)

Michael S. Hirshorn

Bruce Hundertmark

Peter G. Scott

Denis N. Wade

Executive
Michelle Miller 

(Managing Director)

Executives

Peter J. Nightingale 

(Company Secretary) 

Total

Year

2010

2009

2010

2009

2010

2009

2010

2009

2010

2009

2010

2009

2010

2009

2010

2009

Primary Salary
and Fees
$

Post-Employment
Superannuation Benefits
$

55,046

55,046

27,523

27,523

27,523

27,523

20,642

5,000

4,587

-

219,230

200,000

75,000

75,000

429,551

390,092

4,954

4,954

2,477

2,477

2,477

2,477

1,858

25,000

-

-

19,731

18,000

-

-

31,497

52,908

Total
$

60,000

60,000

30,000

30,000

30,000

30,000

22,500

30,000

4,587

-

238,961

218,000

75,000

75,000

461,048

443,000

During 2010 and 2009, no long term benefits, termination benefits or share-based payments were paid.

31

Biotron Annual Report 2010

 
 
 
Equity holdings and transactions
The movement during the reporting period in the number of ordinary shares in the Company held directly, indirectly or beneficially, 
by each specified director and executive, including their personally-related entities, is as follows:

Fully paid ordinary shareholdings and transactions - 2010

Directors

Michael J. Hoy

Michelle Miller

Michael S. Hirshorn

Bruce Hundertmark

Denis N. Wade*

Peter G. Scott**

Executives

Peter J. Nightingale

Held at
1 July 2009

Purchased

Received on
Exercise of
Options

Sales

Held at
30 June 2010

1,408,214

-

-

-

-

9,014,000

1,702,397

-

-

130,000

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1,408,214

-

130,000

-

475,000

-

1,702,397

* Dr Denis N. Wade held 475,000 shares at the time of becoming a director.
** Mr Peter G. Scott held 9,014,000 shares when he resigned as director on 1 April 2010.

Fully paid ordinary shareholdings and transactions - 2009

Directors

Michael J. Hoy

Michelle Miller

Michael S. Hirshorn

Bruce Hundertmark

Denis N. Wade

Peter G. Scott

Executives

Peter J. Nightingale

Held at
1 July 2008

Purchased

Received on
Exercise of
Options

Sales

Held at
30 June 2009

1,345,714

62,500

-

-

-

-

-

-

-

-

8,924,414

89,586

1,639,897

62,500

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1,408,214

-

-

-

-

9,014,000

1,702,397

During the year ended 30 June 2010, Michael J. Hoy had an interest in an entity, CityPrint Holdings Pty Limited, which provided 
printing services to the Company.  Payments to CityPrint Holdings Pty Limited, which were in the ordinary course of business and on 
normal terms and conditions, amounted to $21,239 (2009 - $17,062). Outstanding amounts at 30 June 2010 total $nil (2009 - $nil).

During the year ended 30 June 2010, Peter J. Nightingale had an interest in an entity, MIS Corporate Pty Limited, which provided full 
administrative services, including rental accommodation, administrative staff, services and supplies, to the entity.  Fees paid to MIS 
Corporate Pty Limited during the year, which were in the ordinary course of business and on normal terms and conditions, amounted 
to $121,526 (2009 - $122,025).  Outstanding amounts at 30 June 2010 total $nil (2009 - $nil).

Biotron Annual Report 2010

32

NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2010

Apart from the details disclosed in this note, no director has entered into a material contract with the Company since the end of the 
previous financial year and there were no material contracts involving directors’ interests existing at year end.

Option holdings

The movement during the reporting period in the number of options over ordinary shares in the Company held directly, indirectly or 
beneficially, by each specified director and executive, including their personally-related entities, is as follows:

Option holdings - 2010

Held at
1 July 2009

Purchased

Expired

Held at
30 June 2010

Vested and 
Exercisable
at 30 June 2010

Directors

Michael J. Hoy

Michelle Miller

Michael S. Hirshorn

Bruce Hundertmark

Denis N. Wade*

Peter G. Scott**

Executives

Peter J. Nightingale

500,000

1,500,000

200,000

200,000

-

-

1,408,214

-

-

-

-

500,000

200,000

2,287,785

-

-

-

-

-

-

-

1,908,214

1,500,000

200,000

200,000

162,500

-

1,908,214

1,500,000

200,000

200,000

162,500

-

2,487,785

2,487,785

* Dr Denis N. Wade held 162,500 options at the time of becoming a director.
** Mr Peter G. Scott held 500,000 options when he resigned from office on 1 April 2010.

Option holdings - 2009

Held at
1 July 2008

Purchased

Expired

Held at
30 June 2009

Vested and 
Exercisable
at 30 June 2009

500,000

1,500,000

200,000

200,000

-

200,000

-

-

-

-

-

-

-

-

-

-

-

-

500,000

1,500,000

200,000

200,000

-

500,000

1,500,000

200,000

200,000

-

200,000

200,000

Biotron Annual Report 2010

Directors

Michael J. Hoy

Michelle Miller

Michael S. Hirshorn

Bruce Hundertmark

Peter Scott

Executives

Peter J. Nightingale

33

14.  EMPLOYEE  AND  DIRECTOR  INCENTIVE 
OPTION PLAN

At  30  June  2010,  the  Company  had  4  employees  (2009  -  4).  
All  other  personnel  are  contracted  by  the  Company  on  a 
consultancy basis.

The Company has an Incentive Option Plan to provide eligible 
persons, being employees or directors, or individuals whom the 
Plan Committee determine to be employees for the purposes of 
the Plan, with the opportunity to acquire options over unissued 
ordinary  shares  in  the  Company.    The  number  of  options 
granted or offered under the Plan will not exceed 10% of the 
Company’s issued share capital and the exercise price of options 
will be the greater of the market value of the Company’s shares 
as at the date of grant of the option or such amount as the Plan 
Committee  determines.    Options  have  no  voting  or  dividend 
rights.

In the event that the employment or office of the optionholder 
is terminated, any options which have not reached their exercise 
period  will  lapse  and  any  options  which  have  reached  their 
exercise  period  may  be  exercised  within  three  months  of  the 
date of termination of employment.  Any options not exercised 
within this three month period will lapse.

During the year ended 30 June 2010, no options were granted 
or forfeited to employees (2009 - nil).  No ordinary shares have 
been  issued  as  a  result  of  the  exercise  of  any  option  granted 
pursuant to the Incentive Option Plan during the years ended 30 
June 2010 and 30 June 2009.

15. FINANCIAL INSTRUMENTS DISCLOSURE

The  board  has  overall  responsibility  for  the  establishment  and 
oversight  of  the  risk  management  framework.  Informal  risk 
management policies are established to identify and analyse the 
risks faced by the Company.

The main risks arising from the Company’s financial instruments 
are credit risk, liquidity risk and interest rate risk. The summaries 
below  present  information  about  the  Company’s  exposure  to 
each  of  these  risks,  their  objectives,  policies  and  processes  for 
measuring and managing risk, the management of capital and 
financial instruments.

Credit risk
Credit risk arises mainly from the risk of counterparties defaulting 
on the terms of their agreements. The carrying amounts of the 
following assets represent the Company’s maximum exposure to 
credit risk in relation to financial assets:

Notes

Carrying 
amount

Carrying 
amount

Cash and cash 
equivalents

Trade and  
other receivables

Security deposits

6

7

2010

$

2009

$

1,780,567

950,581

9,471

15,130

27,520

15,130

1,805,168

993,231

The Company mitigates credit risk on cash and cash equivalents 
by dealing with regulated banks in Australia.  Credit risk of trade 
and other receivables is very low as it consists predominantly of 
amounts recoverable from taxation authorities in Australia.

Biotron Annual Report 2010

34

NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2010

Impairment losses
No impairment has been taken up against the Company’s financial assets.

None of the Company’s trade and other receivables are past due and no amount receivable has been renegotiated.

Liquidity risk
Liquidity risk is the risk that the Company will not be able to meet its financial obligations as they fall due.  The Company’s approach 
to managing liquidity is to ensure, as far as possible, that it will always have sufficient liquidity to meet its liabilities when due, under 
both normal and stressed conditions, without incurring unacceptable losses or risking damage to the Company’s reputation. 

The following are the contractual maturities of financial liabilities, including estimated interest payments:

Company

30 June 2010

Carrying
Amount

$

Contractual
Cash Flows

Less Than
One Year

Between One and 
Five Years

Interest

$

$

Trade and other payables

62,212

(62,212)

(62,212)

30 June 2009

Trade and other payables

136,397

(136,397)

(136,397)

$

-

-

$

-

-

Ultimate responsibility for liquidity management rests with the board.  The Company manages liquidity risk by maintaining adequate 
funding and monitoring of future rolling cash flow forecasts of its operations, which reflect management’s expectations of expected 
settlement of financial assets and liabilities.

Interest rate risk
The Company’s income statement is affected by changes in interest rates due to the impact of such changes on interest income from 
cash and cash equivalents and interest bearing security deposits.

At balance date, the Company had the following mix of financial assets exposed to variable interest rate risk that are not designated 
as cash flow hedges:

Financial Assets

Cash and cash equivalents

Security deposits

Net exposure

Note

7

2010
$

1,780,567

15,130

1,795,697

2009
$

950,581

15,130

965,711

35

Biotron Annual Report 2010

 
 
 
Sensitivity analysis
An increase of 100 basis points in interest rates throughout the 
reporting period would have decreased the loss for the period 
by  the  amounts  shown  below,  whilst  a  decrease  would  have 
increased the loss by the same amount. The Company’s equity 
consists of fully paid ordinary shares.  There is no effect on fully 
paid ordinary shares by an increase or decrease in interest rates 
during the period.

30 June 2010

30 June 2009

$

11,276

9,657

16. FINANCIAL REPORTING BY SEGMENTS

The  Company  operates  in  the  biotechnology  industry  in 
Australia.

17. OPERATING LEASE

The Company leases an office in North Ryde Sydney.  The lease is 
currently under negotiations for a period of 3 years starting from 
November 2010 with an option to renew lease after that 3 years.  
Lease payments are increased every year at an increment of 5% 
per annum.  This increment percentage is under negotiation.

During the year ended 30 June 2010, $58,233 was recognised as 
an expense in the income statement in respect of the operating 
lease (2009 - $51,351).

Less than one year

Between one and five years

More then five years

2010

2009

$

24,871

-

-

$

58,831

25,009

-

Capital management
The board’s policy is to maintain a strong capital base so as to 
maintain investor, creditor and market confidence and to sustain 
future development of the business. 

The board ensures costs are not incurred in excess of available 
funds  and  will  seek  to  raise  additional  funding  through  issues 
of  shares  for  the  continuation  of  the  Company’s  operation.  
There  were  no  changes  in  the  Company’s  approach  to  capital 
management during the year.

The  Company  is  not  subject  to  externally  imposed  capital 
requirements.

Net fair values of financial assets and liabilities
The  carrying  amounts  of  financial  assets  and 
liabilities 
approximate their net fair values, given the short time frames to 
maturity and or variable interest rates.

Biotron Annual Report 2010

36

DIRECTORS’ DECLARATION

1.  In the opinion of the directors of Biotron Limited:

a) 

the financial statements and notes set out on pages 17 to 36, and the Remuneration Report in the Directors’ Report, set out  
on pages 11 to 13, are in accordance with the Corporations Act 2001, including:

(i)  giving a true and fair view of the Company’s financial position as at 30 June 2010 and of its performance for the  

financial year ended on that date; and

(ii)  complying with Australian Accounting Standards (including Australian Accounting Interpretations) and the Corporations  

Regulations 2001; 

b) 

the financial report also complies with International Financial Reporting Standards as disclosed in Note 1; 

c) 

there are reasonable grounds to believe that the Company will be able to pay its debts as and when they become due and  
payable.

2.  The directors have been given the declarations required by Section 295A of the Corporations Act 2001 from the chief executive  

officer and chief financial officer for the financial year ended 30 June 2010.

This report has been signed in accordance with a resolution of the directors and is dated 30 August 2010:

Michael J. Hoy   
Chairman 

Michelle Miller
Managing Director

37

Biotron Annual Report 2010

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
INDEPENDENT AUDITOR’S REPORT
TO THE MEMBERS OF BIOTRON LIMITED

appropriate  in  the  circumstances,  but  not  for  the  purpose  of 
expressing an opinion on the effectiveness of the entity’s internal 
control.  An audit also includes evaluating the appropriateness of 
accounting policies used and the reasonableness of accounting 
estimates made by the directors, as well as evaluating the overall 
presentation of the financial report. 

We performed the procedures to assess whether in all material 
respects the financial report presents fairly, in accordance with 
the Corporations Act 2001 and Australian Accounting Standards 
(including  the  Australian  Accounting  Interpretations),  a  view 
which  is  consistent  with  our  understanding  of  the  Company’s 
financial position and of its performance.

We believe that the audit evidence we have obtained is sufficient 
and appropriate to provide a basis for our audit opinion.

Independence
In  conducting  our  audit,  we  have  complied  with  the 
independence requirements of the Corporations Act 2001.  

Report on the financial 
report
We  have  audited  the  accompanying 
financial  report  of  Biotron  Limited  (the 
Company), which comprises the statement of financial position 
as  at  30  June  2010,  and  the  statement  of  comprehensive 
income, statement of changes in equity and statement of cash 
flows for the year ended on that date, a description of significant 
accounting policies and other explanatory notes 1 to 17 and the 
directors’ declaration.

Directors’ responsibility for the financial report 
The  directors  of  Biotron  Limited  are  responsible  for  the 
preparation  and  fair  presentation  of  the  financial  report  in 
accordance with Australian Accounting Standards (including the 
Australian Accounting Interpretations) and the Corporations Act 
2001.  This responsibility includes establishing and maintaining 
internal control relevant to the preparation and fair presentation 
of the financial report that is free from material misstatement, 
whether due to fraud or error; selecting and applying appropriate 
accounting policies; and making accounting estimates that are 
reasonable in the circumstances.

In Note 1 the directors also state, in accordance with Australian 
Accounting  Standard  AASB  101  Presentation  of  Financial 
Statements,  that  the  financial  report  comprising  the  financial 
statements  and  notes  complies  with  International  Financial 
Reporting Standards.

Auditor’s responsibility
Our responsibility is to express an opinion on the financial report 
based  on  our  audit.    We  conducted  our  audit  in  accordance 
with Australian Auditing Standards.  These Auditing Standards 
require  that  we  comply  with  relevant  ethical  requirements 
relating to audit engagements and plan and perform the audit 
to obtain reasonable assurance whether the financial report is 
free from material misstatement. 

An audit involves performing procedures to obtain audit evidence 
about  the  amounts  and  disclosures  in  the  financial  report.  
The  procedures  selected  depend  on  the  auditor’s  judgement, 
including the assessment of the risks of material misstatement 
of the financial report, whether due to fraud or error.  In making 
those  risk  assessments,  the  auditor  considers  internal  control 
relevant to the entity’s preparation and fair presentation of the 
financial  report  in  order  to  design  audit  procedures  that  are 

Biotron Annual Report 2010

38

INDEPENDENT AUDITOR’S REPORT
TO THE MEMBERS OF BIOTRON LIMITED

Auditor’s opinion
In our opinion:

a) 

the financial report of Biotron Limited is in accordance with the Corporations Act 2001, including:  

(i)  giving a true and fair view of the Company’s financial position as at 30 June 2010 and of its performance for the year  

ended on that date; and 

(ii)  complying  with  Australian  Accounting  Standards  (including  the  Australian  Accounting  Interpretations)  and  the  

Corporations Regulations 2001.

b) 

the financial report also complies with International Financial Reporting Standards as disclosed in Note 1.

Material uncertainty regarding continuation as a going concern
Without qualifying our opinion, we draw attention to Note 1, “Going Concern” in the financial report. The conditions disclosed in 
Note 1 indicate the existence of a material uncertainty which may cast significant doubt about the Company’s ability to continue as 
a going concern and, therefore, whether it will realise its assets and extinguish its liabilities in the normal course of business and at 
the amounts stated in the financial report.

Report on the remuneration report
We have audited the Remuneration Report included in pages 11 to 13 of the directors’ report for the year ended 30 June 2010.  The 
directors of the company are responsible for the preparation and presentation of the remuneration report in accordance with Section 
300A of the Corporations Act 2001. Our responsibility is to express an opinion on the Remuneration Report, based on our audit 
conducted in accordance with auditing standards.

Auditor’s opinion
In our opinion, the Remuneration Report of Biotron Limited for the year ended 30 June 2010 complies with Section 300A of the 
Corporations Act 2001.

KPMG 

(cid:3)

Brisbane 30 August 2010

W.E. Austin
Partner

39

Biotron Annual Report 2010

 
 
 
 
ADDITIONAL STOCK EXCHANGE INFORMATION
FOR THE YEAR ENDED 30 JUNE 2010

Home Exchange

The Company is listed on the ASX Limited. The home exchange is Sydney.

Use of Cash and Assets

Since  the  Company’s  listing  on  the  ASX,  the  Company  has  used  its  cash  and  assets  in  a  way  consistent  with  its  stated  business 
objectives.

Class of Shares and Voting Rights

There is only one class of shares in the Company, fully paid ordinary shares.

The rights attaching to shares in the Company are set out in the Company’s Constitution.  The following is a summary of the principal 
rights of the holders of shares in the Company.

Every holder of shares present in person or by proxy, attorney or representative at a meeting of shareholders has one vote on a vote 
taken by a show of hands, and, on a poll every holder of shares who is present in person or by proxy, attorney or representative has 
one vote for every fully paid share registered in the shareholder’s name on the Company’s share register.

A poll may be demanded by the chairperson of the meeting, by at least 5 shareholders entitled to vote on the resolution or shareholders 
with at least 5% of the votes that may be cast on the resolution on a poll.

Distribution of Equity Securityholders

As at 31 July 2009, the distribution of each class of equity was as follows:

Range

Fully Paid 
Ordinary Shares

30 September
2010 $0.35
Options

30 September
2010 $0.40
Options

30 September
2010 $0.45
Options

30 December
2011 $0.10
Options

30 March
2012 $0.20
Options

1 - 1,000

1,001 - 5,000

5,001 - 10,000

10,001 - 100,000

100,001 and over

58

373

303

635

167

1,536

-

-

-

-

12

12

-

-

-

-

2

2

-

-

-

-

1

1

2

38

50

197

124

411

-

20

21

58

11

110

At 31 July 2010, nil shareholders held less than a marketable parcel of shares.

ADDITIONAL STOCK EXCHANGE INFORMATION

Biotron Annual Report 2010

40

ADDITIONAL STOCK EXCHANGE INFORMATION
FOR THE YEAR ENDED 30 JUNE 2010

Twenty Largest Quoted Shareholders

At 31 July 2010 the twenty largest fully paid ordinary shareholders held 42.51% of fully paid ordinary as follows:

Name

Dr Angela Fay Dulhunty

Scott’s A V Pty Ltd

Rigi Investments Pty Ltd

Twynam Agricultural Group Pty Ltd

CBDF Pty Ltd

Pathold No 222 Pty Ltd

Martin Place Securities Staff Superannuation Fund Pty Ltd

Chris and Bhama Parish 

Philip and Marylyn Board 

Linkenholt Pty Ltd

Michael John Hoy

ANZ Nominees Limited

Edstop Pty Ltd

Ian and Marion Platt-Hepworth

Carrington Services Pty Ltd 

Wightholme Nominees Pty Ltd

Peter James Nightingale

Prof Alan Jonathan Berrick

Christopher David Hammer

Ramsab Pty Ltd 

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

There are no current on-market buy-backs.

Fully Paid Ordinary 
Shares

9,968,362

9,014,000

4,492,645

3,700,000

2,875,254

2,650,000

2,300,000

1,600,000

1,599,950

1,500,000

1,408,214

1,358,829

1,248,276

1,228,420

1,200,000

1,200,000

1,175,714

1,150,000

1,090,715

1,000,000

%

8.19

7.40

3.69

3.04

2.36

2.18

1.89

1.31

1.31

1.23

1.16

1.12

1.03

1.01

0.99

0.99

0.97

0.94

0.90

0.82

41

Biotron Annual Report 2010

Principal Administration Office:

Suite 1.9, 56 Delhi Road

NORTH RYDE  NSW  2113

Phone: 61-2 9805 0488

Fax:

61-2 9805 0688

CORPORATE DIRECTORY

Directors:

Mr Michael J. Hoy (Chairman)

Dr Michelle Miller (Managing Director)

Dr Michael S. Hirshorn

Mr Bruce Hundertmark

Dr Denis N. Wade

Company Secretary:

Mr Peter J. Nightingale

Registered Office:   

Level 2, 66 Hunter Street 

SYDNEY  NSW  2000 

Phone:

61-2 9300 3344

Fax:

61-2 9221 6333

E-mail:

enquiries@biotron.com.au

Homepage: www.biotron.com.au

Share Registrar:

Computershare Investor Services Pty Limited

PO Box 523

BRISBANE  QLD  4001

Phone:  61-7 3237 2100

Fax:

61-7 3229 9860

Auditors:

KPMG 

Level 16, Riparian Plaza

71 Eagle Street

BRISBANE  QLD  4000

Home Exchange:

ASX Limited

20 Bridge Street

SYDNEY  NSW  2000

Solicitors:

Minter Ellison

88 Phillip Street

SYDNEY  NSW  2000

Biotron Limited, incorporated and domiciled in Australia, is a publicly listed company limited by shar

ustralia, is a publicly listed company limited by shares.

cly

sh

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BIOTRON LIMITED  Level 2, 66 Hunter Street, Sydney, NSW 2000, Australia

Level 2, 66 Hunter Street 
Sydney  NSW  2000 
Tel: (61-2) 9300 3344 
Fax: (61-2) 9221 6333 
E-mail: pnightingale@biotron.com.au 
Website: www.biotron.com.au 

NOTICE OF ANNUAL GENERAL MEETING 

Notice  is  hereby  given  that  the  Annual  General  Meeting  of  members  is  to  be  convened  at  Level  3,  66  Hunter 
Street, Sydney, NSW, 2000 on 26 November 2010 at 11.00 am. 

AGENDA 

ORDINARY BUSINESS 

To receive and consider the Company's annual financial report, the directors' report and the auditors' report for the 
year ended 30 June 2010. 

To consider and, if thought fit, pass the following resolutions, with or without amendment: 

Resolution 1. 

'That the Remuneration Report for the year ended 30 June 2010 be and is hereby adopted.' 

Resolution 2. 

'That Dr Michael S. Hirshorn be and is hereby re-elected as a Director.' 

Resolution 3. 

'That Dr Denis N. Wade be and is hereby elected as a Director.' 

Resolution 4. 

'That, for the purposes of ASX Listing Rule 10.11, the grant of 5,000,000 options to Michelle 
Miller  in  accordance  with  the  terms  as  set  out  in  the  Explanatory  Memorandum 
accompanying this Notice of Meeting is approved'. 

To transact any other business that may be brought forward in accordance with the Company's Constitution. 

By order of the Board 

Peter J. Nightingale 
Company Secretary 

22 October 2010 

pjn5610 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Level 2, 66 Hunter Street 
Sydney  NSW  2000 
Tel: (61-2) 9300 3344 
Fax: (61-2) 9221 6333 
E-mail: pnightingale@biotron.com.au 
Website: www.biotron.com.au 

EXPLANATORY MEMORANDUM 

This  is  the  Explanatory  Memorandum  Notice  referred  to  in  the  Notice  of  Annual  General  Meeting  of  Biotron 
Limited to be convened at Level 3, 66 Hunter Street, Sydney, NSW, 2000 on 26 November 2010 at 11.00 am. 

Resolution 1  

Adoption of the Remuneration Report 

The  Remuneration  Report,  which  can  be  found  as  part  of  the  Directors’  Report  in  the  Company's  2010  Annual 
Report, contains certain prescribed details, sets out the policy adopted by the Board of Directors and discloses the 
payments to key management personnel, Directors and senior executives. 

In  accordance  with  section  250R  of  the  Corporations  Act,  a  resolution  that  the  Remuneration  Report  be  adopted 
must be put to the vote.  The resolution is advisory only and does not bind Directors. 

Resolution 2  

Re-election of Michael Hirshorn as a Director 

In accordance with Article 58 of the Company's Constitution and the Corporations Law, Michael Hirshorn retires 
as a Director by rotation and, being eligible, offers himself for re-election. 

Resolution 3  

Election of Denis Wade as a Director 

Having been appointed as a Director during the year, in accordance with Article 56 of the Company's Constitution 
and the Corporations Law, Denis Wade retires as a Director and, being eligible, offers himself for election. 

Resolution 4 

Approval of Grant of Options to Michelle Miller 
for the purposes of ASX Listing Rule 10.11 

As part of her remuneration as Managing Director, Resolution 4 proposes the granting of three tranches of options 
to Michelle Miller with the following principal terms and conditions: 

  Class of securities to be issued:  30 October 2015 options 
  Number of options to be issued:  5,000,000 
 
  Entitlement per option: 

Issue price 

  Exercise price per option: 

  Vesting date: 

  Expiry date: 

$nil 
Exercisable at any time after the vesting date and before the expiry date 
to acquire 1 fully paid ordinary share 
the greater of the amount equal to 100% above the market value of the 
Company's shares (as determined under section 139FA of the Income Tax 
Assessment Act 1936) on the date of the grant of the options and: 

  $0.15 for the first tranche of 1,000,000 options 
  $0.20 for the second tranche of 1,000,000 options 
  $0.25 for the third tranche of 3,000,000 options 
Immediately following shareholder approval of the grant 
of options for the first tranche of 1,000,000 options 
30 October 2011 for the second tranche of 1,000,000 options 
30 October 2012 for the third tranche of 3,000,000 options 
the  earlier  of  30  October  2015  and  the  date  which  is  1  month  after  the 
date  of  ceasing  to  be  an  officer  of  the  Company  (other  than  due  to  the 
occurrence of a Special Circumstance as defined by the Biotron Incentive 
Option Plan) 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
By  obtaining  shareholder  approval  for  Resolution  4  as  required  by  ASX  Listing  Rule  10.11,  the  Company  will 
satisfy the requirements of Exception 14 of ASX Listing Rule 7.2 and thereby not require shareholder approval for 
these issues under Listing Rule 7.1. 

The options issued under Resolution 4 allow for the rights of the optionholder to be changed to comply with the 
ASX  Listing  Rules  applying  to  a  reorganisation  of  capital  at  the  time  of  the  reorganisation.    The  optionholder 
cannot participate in new issues without exercising the options. 

All options granted under Resolution 4 may be allotted immediately following shareholder approval at the Annual 
General Meeting and, in any event, within one month following the close of the meeting. 

No funds will be raised from the issue of the options.  In the event that any of the options are exercised, the funds 
raised will be used to continue the development of the Company's biotechnology projects and for working capital 
purposes. 

The  options  which  may  be  granted  are  intended  to  provide  an  incentive  to  Michelle  Miller  to  recognise  her 
contribution  to  the  Company.    The  Directors  consider  that  the  incentive  represented  by  these  options  is  a  cost 
effective and efficient incentive offered by the Company when compared with alternative forms of incentive such 
as cash bonuses or increased remuneration. 

Voting Exclusion Statement 

The Company will disregard any votes cast on Resolution 4 by: 

  Michelle Miller; and 
  any associates of Michelle Miller. 

However, the Company need not disregard a vote if: 

  it is cast by a person as proxy for a person who is entitled to vote, in accordance with the directions 

on the proxy form; or 

  it  is  cast  by  the  person  chairing  the  meeting  as  proxy  for  a  person  who  is  entitled  to  vote,  in 

accordance with a direction on the proxy form to vote as the proxy decides. 

 
 
 
 
 
 
 
 
 
 
 
 
 
Level 2, 66 Hunter Street 
Sydney  NSW  2000 
Tel: (61-2) 9300 3344 
Fax: (61-2) 9221 6333 
E-mail: pnightingale@biotron.com.au 
Website: www.biotron.com.au 

FORM OF PROXY 

I/we . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  

of . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  

being a member/members of Biotron Limited HEREBY APPOINT 

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  
or failing him, the Chairman of the Meeting, as my/our Proxy to vote for me/us and on my/our behalf at the Annual General 
Meeting of Members of the Company to be held at 11.00 am on 26 November 2010 and at any adjournment thereof. 

The Proxy is directed by me/us to vote as indicated by the marks in the appropriate boxes below: 

RESOLUTION 

1.  Adoption of the Remuneration Report 

2.  Re-election of Michael S. Hirshorn as a Director 

3.  Election of Denis N. Wade as a Director 

4.  Approval of the grant of options to Michelle Miller 

  FOR 
   □ 
   □ 
   □ 
   □ 

AGAINST 
    □   
    □   
    □   
    □   

ABSTAIN 
  □ 
  □ 
  □ 
  □ 

If no directions are given, the Proxy may vote as the Proxy thinks fit or may abstain. 

If you do not wish to direct your Proxy how to vote, please place a mark in the box: 
By marking this box, you acknowledge that the Chairman may exercise your proxy even if he has an interest in the outcome of 
the resolution and votes cast by him other than as proxy holder will be disregarded because of that interest.  The Chairman 
intends to vote undirected proxies in favour of each item. 

□ 

Dated this . . . . . . day of . . . . . . . . . . . . . . . . . . . . . . 2010 

Signatures of Member(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 

THE COMMON SEAL of . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A.C.N. . . . . . . . . . . . . . . . . . . . .   

was hereunto affixed in accordance with 

its Constitution in the presence of: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  

        Director 

Secretary 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
  
 
 
  
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
PROXY INSTRUCTIONS 

A member entitled to attend and vote is entitled to appoint not more than 2 proxies. 

1. 
2.  Where  more  than  1  proxy  is  appointed,  each  proxy  must  be  appointment  to  represent  a  specified 

3. 
4. 
5. 
6. 
7. 

8. 

9. 

proportion of the member's voting rights. 
A proxy need not be a member. 
Companies must sign under seal. 
All joint holders must sign. 
All executors of deceased estates must sign. 
The Company will disregard any votes cast on Resolution 4 by: 

  Michelle Miller; and 
  any associates of Michelle Miller. 

However, the Company need not disregard a vote if: 

  it is cast by a person as proxy for a person who is entitled to vote, in accordance with the directions on 

the proxy form; or 

  it  is  cast  by  the  person  chairing  the  meeting  as  proxy  for  a  person  who  is  entitled  to  vote,  in 

accordance with a direction on the proxy form to vote as the proxy decides. 

The  Company  has  determined,  in  accordance  with  regulation  7.11.37  of  the  Corporations  Regulations 
2001  (Cth),  that  the  Company's  shares  quoted  on  the  Australian  Stock  Exchange  Limited  at  7.00  pm 
Sydney time on 24 November 2010 are taken, for the purposes of the Annual General Meeting to be held 
by the persons who held them at that time.  Accordingly, those persons are entitled to attend and vote (if 
not excluded) at the meeting. 
Proxy  forms  must  be  received  at  the  Company's  registered  office,  Level  2,  66  Hunter  Street,  Sydney, 
NSW, 2000, or by facsimile on (61-2) 9221 6333, not less than 48 hours before the time appointed for 
holding the meeting. 

pjn5610