Emyria
Annual Report 2021

Plain-text annual report

World-class team Meet the innovators Novel methodology Aggregated research is Drug registration Moving towards drug $EMD on the ASX A year defined by pivotal harnessing the potential informing development registration for potential milestones and strong of real world evidence of novel treatments drug candidates shareprice appreciation 06 08 12 16 Annual Report 2021 Is there a better way to get better? 2 Yes. By developing technology-powered health services that elevate clinical care and deliver deeper clinical insights. By learning from every patient. By testing and validating novel treatments in the real world. In real time. By collecting and systematising live, dynamic, multidimensional patient data and clinical evidence. By making patients part of the clinical research journey and clinical innovation part of every patient’s health journey. Welcome to Emyria and evidence-generating care. ASX:EMD ABN 96 625 085 734 emyria.com COMPANY SNAPSHOT 3 Contents Letter from the Chairman Page 04 Meet the Team Page 06 Company Snapshot Page 08 Patient Feature Page 10 Drug Development Page 12 Review of Operations Page 14 Clinician Feature Page 20 Opioid Reduction Impact MDMA Assisted Therapy Emerald Clinics Feature Page 22 Page 24 Page 26 Directors’ Report Financial Report Consolidated Statement of Profit or Loss and Other Comprehensive Income Consolidated Statement of Financial Position Consolidated Statement of Changes in Equity Consolidated Statement of Cash Flows Notes to the Consolidated Financial Statements Directors’ Declaration Auditors’ Independence Declaration Independent Auditor’s Report Corporate Governance Statement ASX Additional Information Corporate Directory 28 44 45 46 47 48 49 79 80 81 88 97 101 4 Letter from the Chairman With utmost gratitude, I write to thank our valued shareholders and supporters for helping to shape our Company this Financial Year (FY21) – a period of significant growth, advancement of our clinical data into drug products and expansion of our product range to include psychedelics. Emyria has secured its reputation as a Company on the move. In August 2020, we launched a new parent brand – Emyria Ltd, retaining ASX ticker code EMD. I often get asked how to pronounce the new name, it is ‘Em-mee-ria’ derived from the word Myriad. The goal of this new name is to provide strong foundations for growing our clinical services division under Emerald Clinics (Emyria Care); our real world evidence asset portfolio and data systems (Emyria Data); and the registration of novel drugs for unmet needs (Emyria Treatments). Together, our business units work harmoniously 5 services model. We also secured a partnership with Mt Sinai’s Precision Recovery team in New York to support remote patient monitoring and care. Clinical research partnerships were also established with Mind Medicine Australia and Zelira (ASX:ZLD). Looking ahead, we are excited to see all the moving parts of our Company coming together, which we have worked extremely hard to build, and to expand the reach of our key programs in the real world, with real people. We remain committed to serving our patients, our clinician network, our investors, our commercial partners, and other vital stakeholders in such a way that retains our commitment to ethical innovation. As Chairman, I would like to thank everyone who has played such an important role in our progress this Financial Year, and look forward to continuing our shared journey to positively impact peoples’ lives. With thanks, Dr Stewart Washer Emyria Chairman and simultaneously to give people better ways to get better. Our goal is to achieve unprecedented efficiencies in the way our sector can test the merits of novel treatments – by providing high quality evidence- based care that generates valuable data that we use to design new drug treatments. . This has resulted in the launch of our drug development program in FY21, which soon became three, with more on the horizon too. We are continuing to work closely and productively with regulators seeking rapid approval for our products. This Financial Year, we have gained TGA approvals for our remote digital health monitoring technology and are working to secure registration for our medicinal cannabis drug products. This is an essential part of Emyria’s success that differentiates us from other medical cannabis or psychedelic medicinal drug companies. I am proud to say these achievements have been supported by strategic and sustainable corporate governance. This Financial Year we raised $8.4m, with tax incentives and grants delivering more than $1.8m in addition to this. This capital will facilitate steady growth across our clinical services, drug development programs, and ongoing research and development too. “We provide safe and tested avenues for patients to try promising new treatments - and we develop them too - with the best clinical evidence systems and support teams in place. Our patients receive the personalised care they truly deserve, with an opportunity to contribute to, and benefit from, Emyria’s growing body of clinical data and insights.” While strengthening our foundations, our team is always looking up and out to opportunities at home and abroad – to learn, to collaborate, to lead – and this Financial Year we have secured strong partnerships. This included signing a real world evidence contract with the world’s largest cannabis company, Canopy Growth in the UK, to expand the Emerald Clinics’ clinical 6 MEET T HE TEAM Professionals with purpose Board Dr Stewart Washer Executive Chairman Board Dr Michael Winlo Managing Director Board Dr Alistair Vickery Medical Director Board Prof Sir John Tooke Non-Executive Director & Chair of the Medical Advisory Board Matt Callahan Non-Executive Director Medical Advisory Board Dr Jennifer Morgan Medical Advisory Board Dr Philip Finch Medical Advisory Board Dr Richard Magtengaard Strategic Advisory Board Dr Karen Smith Chair Strategic Advisory Board Dr Nik Zeps Strategic Advisory Board Dr David Putrino Visit our website at emyria.com/team to view the full credentials of our team. 7 “At Emyria, we are proud to offer personalised care via Emerald Clinics (Emyria Care), underpinned by clear evidence protocols and technology infrastructure (Emyria Data). This framework is efficient, safe and effective for supporting our patients, whilst simultaneously supporting the development and registration of novel drugs (Emyria Treatments) in compliance with key regulators.” Dr Michael Winlo, MD 8 Unlocking the potential of novel treatments We’ve developed a world-class framework for health innovation, combining personalised clinical services and responsive technology infrastructure, to fast-track the development of novel drugs. Evidence-based care. It’s a cornerstone of modern medicine, a standard that patients and regulators alike have come to expect, and rightfully so. At Emyria, we believe that our approach to cultivating and applying evidence is part of a long overdue renaissance for healthcare. Emyia leverages the capabilities of proprietary data systems to collect evidence in the clinic and beyond, in real time, to measure the effectiveness of novel treatments. This Financial Year, Emyria announced a step into end-to-end drug development and registration too, which is a crucial new piece in the Company’s purpose-built evidence production line. Emyria is rapidly expanding, with real world evidence (RWE) in its DNA, having established its place in the market just prior to the COVID-19 pandemic taking hold. As traditional clinical research and drug development models have adjusted (and in many cases, disbanded) to cope with the pandemic, RWE has now emerged as a viable (and indeed essential) way to continue clinical trials – embraced by even the most conservative players in healthcare. Creates Informs • Access to patients and clinicians • Data capture technology • Ongoing patient monitoring and evaluation Emyria Care Emyria Data Drug development • We learn from every patient to improve care • In-house analytics • Clinical trial and drug registration expertise Informs Accelerates COMPANY SNAPSHOT 9 Our work Emyria creates drug development programs backed by its proprietary clinical evidence, while caring for patients with unmet needs. Emyria’s subsidiary company, Emerald Clinics, has seven sites in Australia and has treated more than 4,500 patients – underpinned by a data system that has already gathered millions of data points. “At Emyria, we offer personalised care via Emerald Clinics (Emyria Care), underpinned by clear evidence protocols and technology infrastructure (Emyria Data). This framework is efficient, safe and effective for supporting our patients, whilst we simultaneously develop and pursue registration for promising new drugs informed by our data (Emyria Treatments) and in compliance with key global regulators,” said Emyria Managing Director, Dr Michael Winlo. Emyria is leading the market with sophisticated RWE generating systems. It has supportive technology that captures data in an ethical way and delivers insights back to patients and clinical teams so they can respond in a timely fashion – with examples including adverse event monitoring, precise product selection and personalised dosing. “We strongly believe that by using the principles of a learning health system, we can protect public safety and accelerate the registration of novel treatments and the development of new care models, while alleviating the suffering of so many people,” said Dr Winlo. Our Methodology Emyria’s focus is broad and ambitious – and includes one-to- one and aggregated research on a wide range of novel treatments tackling challenging clinical conditions where there are high unmet needs. Think medicinal cannabis, psychedelics, and other unregistered treatments that are in high demand to meet unmet patient needs. “The health industry has a strong focus on ‘evidence- based medicine’, but traditional evidence generation takes a long time and it is extremely difficult to systematically incorporate all the new knowledge being presented in publications each day with embedded clinical workflows,” said Dr Winlo. “Our workflows are developed in such a way that we collect, measure and learn from the experience of every single patient – and importantly, through intelligent data systems, contextualise these learnings against the masses to derive meaning. This year, Emyria has expanded the reach of this vital work by partnering with other like-minded organisations and other listed companies too. “We provide safe and tested avenues to try novel drugs, with ethical partnerships, clinical evidence systems and support teams in place. Our patients are treated with the level of personalised care they deserve, with an opportunity to contribute to, and leverage, Emyria’s growing body of aggregate clinical data and insights.” Emyria is scientific in its approach to understanding peoples’ clinical experiences and outcomes in the context of real life, not just as a single touchpoint with their care team. The ultimate goal? Proactive and intelligent healthcare. 5,000 patients 2-98 years of age 40+ clinical indications 10 PAT I EN T FEATU RE The pursuit of pain-free living Sometimes in life, time seems to stop. Usually when something profoundly significant, often permanent, happens. Something that changes a person, for better or worse. For Steve*, he can now speak freely about one of those moments – a workplace accident that happened back in 1999 – but not without reference to its daily impact. Now a permanent and often troublesome part of his life. “I used to work for a ship builder in Perth and I lost my leg in an accident between two boats. Just like that, I became an above-knee amputee,” he said. After navigating the initial shock, recovery and lengthy rehabilitation from his accident, Steve started looking for solutions straight away. “I was determined to get back on my feet and started wearing a prothesis. Then in 2014, I had a new procedure called osseointegration surgery, which involved putting an implant into my femur that sticks out of the bottom of the stump, and connects the prothesis to my skeleton. It was life-changing. I was really mobile again and Sometimes in life, time seems to stop. Usually when something profoundly significant, often permanent, happens. Something that changes a person, for better or worse. 11 could do pretty much whatever I want,” said Steve. Even so, side effects from his injury began to re-emerge – in his words, “often excruciating pain, like crushing or stabbing”. The pain primarily consisted of nerve pain, soft-tissue pain in his stump and phantom pain, located where his foot used to be. Steve also began to experience a gradual decline in mental health and quality of sleep – linked directly to post traumatic stress from his accident and managing intermittent, but serious, pain. His health was further compromised by a long-standing diagnosis of ulcerative colitis, which had resulted in the removal of his large bowel in his early twenties and ongoing symptoms, including frequent trips to the toilet. “I could go a week or two with no pain, but then I’d often have a two or three day period where the pain would be really bad. Like an electric shock going off in my stump every thirty seconds. It could last for days, which means I just didn’t sleep,” he says. “It snowballed from there. I would get really tired, and that made it worse. Sometimes I would take medication, to knock it on the head, but sometimes it just didn’t work. It wore thin and it made me short tempered, which isn’t fair on anyone.” medicinal cannabis. They’d had some good results. So, I spoke with my GP for quite a while about it and he was really supportive. After doing a lot of research, we decided to start treatment in partnership with Emerald Clinics,” he says. His treatment started around seven months ago, and despite fighting a significant infection in his stump during that time, the results have been outstanding. “I currently take CBD oil in the morning and again at midnight, and then a further dosage of THC in the evening. It helps me to relax and get to sleep.” “During every appointment at Emerald Clinics, I have to fill out a wellbeing survey and they tweak my treatments slightly, so everything is personalised. I am all for continued research,” says Steve. So is it helping? So far, so good. “It’s definitely improved my overall health, and my wife agrees. It’s helped me sleep better, I don’t rush to go to the toilet anymore, and my mental health has improved vastly too.” Steve is proud and committed to contributing to ongoing medical research with Emerald Clinics, a cornerstone of our model of care. * Pseudonym used to protect the patient’s identity. “During every appointment at Emerald Clinics, I have to fill out a wellbeing survey and they tweak my treatments slightly, so everything is personalised. I am all for continued research,” says Steve. Now 52 years of age and a proud father of two, Steve has remained solutions-focused in managing the changing needs of his disability. As a small business co-owner too, with 10 employees, he simply needed to get well. On his pursuit for a pain-free life, and improved general and mental health, Steve started investigating the merits of medicinal cannabis treatments. In his eyes, and many of his long-term specialists too, it was a somewhat controversial path forward – but he was curious and highly motivated to give it a go, in the bounds of ethical and evidence-based care. “Through word of mouth, and from a few other amputees I know, I learnt more about Want to book an appointment with Emerald Clinics? Visit emeraldclinics.com.au or phone 1300 436 363 12 DR UG DE VELOPMENT Global drug registration Emyria is steadily progressing the development of novel drug candidates - unlocking the true potential of its purpose-built ecosystem for innovation. Responding to unmet patient needs Emyria is proud to offer a patient-centric care model, which includes the provision of in-person and telehealth clinical services, de-identified patient data aggregation, and most recently, novel drug development too. Our Company is now moving methodically towards global drug registration for three potential drug candidates, each requiring different levels of clinical management and regulatory oversight too, as mandated by the Therapeutic Goods Administration (TGA) in Australia. These include EMD-003, a CBD medicine targeting mental health; EMD-004, a CBD/THC medicine targeting irritable bowel syndrome (IBS); and EMDMA-001, an MDMA treatment for post-traumatic stress syndrome (PTSD). Even as a relatively young company, it has become abundantly clear that the insights gathered through our clinics (Emerald Clinics), are extremely valuable for quantifying the efficacy of the novel treatments we offer (primarily medicinal cannabis) – so the next logical and ethical step, is to apply these 13 Less Disease severity (Clinical management intensity) Greater EMD-003 Cannabinoid medicine (over-the-counter) for psychological distress EMDMA-001 Psychedelic-assisted therapy for PTSD S3 S4 S8 S9 TGA Schedules “We now have seven clinical sites around Australia, over 5,000 patients, some 40 clinical indications and a community of world-class clinical advisors and innovators guiding us. This is already translating to efficient and highly effective drug development.” We specialise in the collection of robust and ethically-sourced real-world patient data, which provides an edge for novel drug development. methodologies and learnings to novel drug development too. Currently in Australia, these treatments can only be accessed via Authorised Prescribers (i.e. health practitioners authorised to prescribe therapeutic goods which aren’t currently included in the Australian Register of Therapeutic Goods), Special Access Schemes or clinical trials. Now, through a greater investment in drug development and registration, Emyria is on track to make more treatments more widely available. “There are now around 370 Authorised Prescribers in Australia, which is to be celebrated – but with around 42,000 general practitioners we still have a long way to go before novel treatments can be easily accessed by those in need. Pursuing drug registration is definitely part of the answer and a considerate thing to do for our patients,” said Emyria MD, Dr Michael Winlo. Emryia’s clinics are gathering millions of unique data points every single day, which is an intelligent model for patient care and drug design. Emyria’s current drug registration programs EMD-003 CBD medicine targeting mental health EMD-004 CBD +/- THC for irritable bowel syndrome EMDMA-001 for post traumatic stress syndrome 14 REV IEW O F O P ERAT IONS Review of operations Emyria, together with its network of clinics and diversified suite of technology assets, has experienced a compelling period of growth in the 2020-2021 financial year. Our Company embraced a new name and brand identity as Emyria Limited. In August, after a carefully planned branding process, we launched our new parent company (retaining ASX ticker code EMD) to provide strong foundations for our clinical services, RWE asset portfolio and cornerstone international partnerships too. Supported by the tagline ‘Myriad Data. Individual Care.’, the Emyria team is committed to providing the highest standards of evidence- generating, personalised healthcare. Our financial position is strong. Collectively, our Company has raised $8.4m in heavily subscribed placements, together with a grant to be delivered over two years worth an additional $320,000 and a research and development (R&D) tax incentive refund of $954,180. This capital provides robust foundations for our clinical services, drug development programs, and continued R&D and business development activities too. 15 Emyria launched its first drug development program - and more. Perhaps the most exciting development in FY21, was the launch of Emyria’s evidence- based drug development program focused on mental health (EMD-003); a second program, focused on IBS (EMD- 004); and a third program, focused on a psychedelic-assisted therapy program in partnership with Mind Medicine Australia (EMDMA-001). A commitment to working closely and productively with regulators is continuing to serve us well. We have attracted TGA approvals for our remote monitoring technology and are moving strategically towards drug registration for our medicinal cannabis drug portfolio too. Emyria has attracted consistent interest from mainstream and industry media. Highlights include our Openly remote vital signs monitoring technology profiled on Channel 9’s The Today Show in August 2020; our medicinal cannabis clinical trial to support people with Autism Spectrum Disorder (ASD) covered by Channel 7 News in November 2020; talk-back radio interviews in all states and territories on leading channels including ABC, Triple M, 6PR and more; and an opinion editorial by Emyria MD, Dr Michael Winlo, published in The Canberra Times (and widely syndicated), titled ‘Psychedelic substances represent a chance to alleviate Australia’s mental health crisis’. Emyria’s Managing Director, Dr. Michael Winlo discusses ongoing research into cannabinoid treatment for autism. Emyria’s Managing Director, Dr. Michael Winlo introduces Emyria’s TGA-approved, remote monitoring smartphone platform Openly. Strong international partnerships are defining our commitment to collaborative learning in healthcare. In late 2020, Emerald signed a RWE contract with the world’s largest cannabis company, Canopy Growth in the UK, to expand its clinical services model. Soon after, a partnership was established with Mt Sinai’s Precision Recovery team in New York to support remote patient monitoring and care. Also significant, Emyria’s clinical research partnerships established with Mind Medicine Australia and Zelira (ASX:ZLD). 16 REV IEW O F O P ERAT IONS Milestones and momentum 20/21 August 2020 • Emerald signed RWE contract with Canopy Growth in the UK – the world’s largest cannabis company. The deal leverages Emerald’s data expertise to monitor the safety, efficacy and pharmacoeconomics of medicinal cannabis products. • New parent company name and brand introduced, Emyria Ltd, to support the growth of RWE asset portfolio and developing international partnerships. • Emyria successfully raised $2.2m in a placement to support the growth of its clinical services, R&D and business development activities. >$700 thousand contract with Canopy Growth $2.2 million raised for growth The launch of our new name and brand September 2020 • Emerald received TGA registration for its Openly App as a medical device – expanding its commitment to providing remote health and wellness services for at-risk and defined community cohorts. • Emerald partnered with Mt Sinai’s Precision Recovery team in New York to support remote patient monitoring and care, with an initial focus on people at risk and/or experiencing COVID-19. • Zelira (ASX:ZLD) signed RWE data agreement with Emyria for insomnia drug Zenivol™, work which will take place in Emyria’s network of specialist medical clinics. 17 December 2020 • Emyria launched its second drug development program focused on IBS (EMD- 004) as part of its CALM-GUT study being conducted in Victoria, New South Wales and Western Australia. > $1.2 million successfully raised in an oversubscribed placement to accelerate its drug development programs October 2020 • Emyria entered into a global partnership with Sapphire Medical Clinics in the UK, to collaborate in the collection and analysis of quality de- identified clinical evidence for people undertaking medicinal cannabis treatments. November 2020 • Emyria received an R&D tax incentive refund of $954,180. • Emyria secured a deal with Zelira (ASX:ZLD) to collect efficacy and safety data from patients with Autism Spectrum Disorder (ASD) who have been prescribed one or more of its HOPE™ products. The trial is one of the largest medicinal cannabis studies ever undertaken. > Emyria partnered with Mind Medicine Australia to develop a national care program and data registry for psychedelic- assisted therapies, leveraging Emyria’s RWE data platform. • Emyria launched its own evidence- based drug development program (EMD-003) focused on mental health – primed for rapid development and registration, due to unparalleled access to large patient populations and expertise in data analysis, clinical trial design and drug registration. The launch of our new name and brand 18 REV IEW O F O P ERAT IONS January 2021 • Emyria announced plans to register EMD-003 in CY2021 to treat symptoms of anxiety, depression and stress – following the February 2021 • Emyria won a digital health monitoring grant worth $880,000 with UWA, to TGA’s ruling to down-schedule Australian registered low-dose boost digital health infrastructure in WA CBD as a Schedule 3 Pharmacist-only medication. by monitoring vital signs and mental health of specific cohorts. > Emyria added a second site in Melbourne for its Emerald Clinics network and engaged a regulatory consultancy ahead of EMD- 003 registration trials. • Emyria welcomed experienced pharmaceutical expert, Dr Karen Smith, to its Strategic Advisory Board. She has led multiple successful drug registrations and strategic partnerships in biopharma. March 2021 • Emyria added a second site in Perth for its Emerald Clinics network ahead of EMD-003 registration trials. > Emyria and Cann commenced exploration of partnership to accelerate the registration of a Schedule 3, over-the-counter, cannabidiol (CBD) medicine to treat unmet needs in mental health. 19 April 2021 • Emyria successfully raised $5m in a placement to advance drug registration for EMD-003 and EMD-004, and to expand its pipeline to include a psychedelic- assisted therapy clinical trial in partnership with Mind Medicine Australia. $5m raised to advance drug registrations May 2021 • Emyria and Mind Medicine Australia announced plans to launch a psychedelic-assisted therapy program June 2021 • Widespread analysis of dispensing data showed a (EMDMA-001) for post traumatic stress disorder (PTSD). significant reduction in opioid This will include evidence-based MDMA-assisted therapy, use following personalised supported by Emyria’s established clinical and data infrastructure. • TGA approval granted for Emyria’s medical grade ‘smartphone camera home cardiovascular monitoring application software’. This technology supports Emyria’s objectives in drug development, telemedicine and consumer healthcare projects. cannabinoid treatment programs at Emerald Clinics. Data provided by IQVIA (NYSE:IQV) and NostraData, validates the quality of Emyria’s evidence-generating data systems and its potential utility for health insurers and other payers. > Emyria filed additional patents supporting its EMD-004 drug development program targeting IBS. • Highly credentialed Principal Investigator and Consultant Psychiatrist, Dr Eli Kotler, appointed to lead Emyria’s MDMA trial for PTSD in partnership with Mind Medicine Australia. 20 C L I N I C I A N F E AT U R E Meet Dr David Gunn An integral contributor to the Emerald Clinics team, who has jumped in headfirst to leverage the capabilities of our proprietary clinical service model from his general practice in the Northern Rivers region of NSW. Innovation is in his veins and Dr Gunn isn’t scared of a challenge, which makes him a perfect fit for Emerald. Working remotely from the Emerald HQ, supported by our world-class tech, made sense to the GP who was seeking greater access to novel treatments for his patients. His clinics in Goonellabah and Alstonville in NSW are a stone’s throw from Nimbin, which has an established culture around the use of cannabis in Australia. There, according to Dr Gunn, the community is in many ways conflicted about how novel treatments, such as medicinal cannabis, intersect with conventional medicine. It’s a bridge he’s walking carefully, every day, but so far with great success. “Medicinal cannabis wasn’t exactly mainstream back home in Canada, but it was certainly available and established in practice. After moving to Australia to work as a GP, I realised very early on that integrating medical 21 cannabis into my work was going to be very difficult. The reactions I got from other doctors was unexpected too,” said Dr Gunn. As a newcomer to the region, he first spent a lot of time understanding and respectfully observing how it all fits together. “Initially, I held back – I didn’t know what was possible and how I could prescribe it in Australia– but then I started educating myself. I reached out to others who were leading access channels to medicinal cannabis and other novel treatments in Australia, which is when I met the team at Emerald Clinics.” After a meeting with Emerald’s Chief Operating Officer and Co-Founder, Adam James, Dr Gunn felt confident that the Company’s research-centric and data-backed care model was exactly what he was looking for to grow his practice and support his patients. “I have many years of experience practicing emergency, palliative, addictions and chronic disease medicine – and over the years I have focused on helping people with difficult to treat problems like chronic pain and insomnia. Working closely with others who have a commitment to evidence-based practice and novel treatments in this area, is definitely appealing,” said Dr Gunn. In reference to his prior experience prescribing novel treatments overseas, Dr Gunn said that what he has seen over the years, is that cannabis is a generally safe and useful treatment that in his opinion “reduces chronic suffering” – but remains committed to testing and proving its merits via the regulated channels established by Emerald Clinics here in Australia. Contributing evidence, he says, is key. “I started by just putting my hand up and saying ‘I’m a real doctor, and cannabis is useful and safe – and maybe we should talk about it some more’. Soon after, Emerald provided me with an opportunity to shift out of my GP practice, without diverting my whole focus away from regular general practice, together with an effective framework for prescribing and researching cannabis with my patients too,” said Dr Gunn. And so far, he’s finding the workflow hugely beneficial – both for patient and clinic. His long term goal is to use these learnings to improve patient outcomes, particularly those with chronic unmet needs that vastly impact their quality of life. “I’m hoping to find a way to improve how those of us in general practice can manage chronic suffering from illnesses like chronic pain– it’s the opposite of the emergency room which is about identifying the problem and addressing it in the moment. In general practice, you are the home base, so chronic ailments “I love seeing patients at Emerald Clinics because of the increased time and care that this model allows. I really do value the research side of things, and it’s structured in such a way that it supports the way I see and treat my patients – rather than getting in the way. Making the time to do it has been quite amazing actually.” that just don’t get better, become an issue for the patient and for the clinic. If they are aren’t dealt with, patient satisfaction is low, doctors become frustrated and it puts pressure on the whole model. We can and should do this better,” said Dr Gunn. Part of that involves, in his opinion, testing and analysing the merits of novel treatments like medicinal cannabis. It’s part of his tool kit and in time, he hopes to see it more widely embraced. “Profound safety is what gets this thing started – we have safety data from thousands of years of human use of cannabis. In my opinion, that cannot be ignored. Combined with the fact that it seems to make peoples’ lives better, that’s how I justify prescribing it.” Want to book an appointment with Dr Gunn? If you’re in Northern Rivers in NSW visit emeraldclinics.com.au or phone 1300 436 363 22 O P I O I D R E D U C T I O N I M PAC T Personalised care helps reduce opiate use for chronic pain Improving the lives of people with unmet medical needs is central to our mission at Emyria - reducing chronic pain, a compelling focus area. Emyria’s Personalised Care Model Helps To Reduce Opiate Use Among Sufferers of Chronic Pain. in patients suffering from chronic pain, as well as improved quality of life. Analysis by independent third- party health analytics provider, IQVIA, has revealed compelling insight into the impact of Emyria’s highly individualised care model, combined with medicinal cannabis treatment, on opiate use. The data was sourced from community pharmacy medication usage of 470 patients in care with Emyria for longer than 12 months. It showed that the average daily opiate dose of these patients decreased substantially after entering the Emyria care model. The data, announced in June 2021, showed Emyria’s care model has a significant, tangible impact on reducing opiate usage The patient cohort represented by the data are located across Australia, with many suffering accompanying symptoms 23 of anxiety and depression associated with their long- standing chronic pain. The average age of patients is around 60 years of age and 60 percent are female. Emyria Managing Director, Dr Michael Winlo, said these results demonstrate the value of Emyria’s comprehensive data registry of over 5,000 patients, and through real world data, strong evidence that Emyria’s care model is helping people who have exhausted other treatment options. “Opiate mis-use is a massive global health concern and cost, so effective reduction approaches have wide implications for care and the health system across the board,” said Dr Winlo. “What these data show us is that there is hope for people who are suffering from chronic pain, for whom other treatments have not been effective.” There’s a plethora of possibilities represented in these data. Emyria’s key findings “As our evidence grows that our care model is effective, we hope to work with insurers to try and provide a more cost-effective solution for patients looking to improve their quality of life,” said Dr Winlo. The data showed Emyria’s care model has a significant, tangible impact on reducing opiate usage. Patients with 6+ months in the Emyria care model and also on cannabinoid medicine saw their average daily opiate dose drop nearly 30% after showing no change in opioid usage in the 12 months prior Patients with less than 6+ months within the care program usage saw a smaller but statistically significant drop in average daily opioid use with an increasing opioid usage pattern in the 12 months prior to receiving care On average nearly 90% of Emyria chronic pain patients have had their condition for more than 2 years On average pain severity, pain interference and other quality of life measures also improved for patients in the Emyria care program 1 2 3 4 24 M D M A-A S S I S T E D T H E R A PY New clinical model to determine if psychedelic drugs can safely treat mental health conditions Emyria has launched a new research program to establish if psychedelic substances can be used as an effective and safe treatment to address the mental health crisis affecting Australia and the world. Initiated in partnership with mental health charity, Mind Medicine Australia, the goal of this program is to establish a gold-standard, data-driven clinical model for the safe provision of psychedelic- assisted therapies in Australia for conditions such as post- traumatic stress disorder, depression and substance abuse. “45% of Australians will suffer from a mental illness in their lifetime,” said Mind Medicine Australia Chairman Peter Hunt AM. Australia’s Productivity Commission estimates that mental illness costs Australia’s economy $220 billion a year. Behind that number is an enormous amount of human suffering. “It’s a national crisis at both a health and economic level, and the current treatments don’t help a large number of Australians and, even when they do, they can have nasty side effects. We need to be innovative and develop much more effective treatment options,” said Mr Hunt. Evidence to date shows that psychedelic-assisted therapies have the potential to treat the root cause of key classes of mental illness such as depression, PTSD and substance abuse – rather than the symptoms – and may work when these conditions are resistant to traditional therapies. Emyria Managing Director, Dr Michael Winlo, said the first priority with any new or experimental treatment is to establish safety. “Our specialty at Emyria is fulfilling an unmet need amongst patients – people who have exhausted their options,” said Dr Winlo. “We’re now designing this model to determine the safe and effective delivery of psychedelic-assisted therapies by collecting data from the real- world experiences of patients, including their diagnosis, accompanying medications, dosing information and response to treatments.” Part of why this model is so important is the ability to demonstrate if and how these substances can be used safely and positively in medically- controlled environments, and move beyond the idea that psychedelic substances only have illicit uses. Trials and research to date into the benefits of psychedelic- assisted therapies have indicated high remission rates with minimal treatments and side effects. Emyria MD, Dr Michael Winlo, authored an opinion editorial for the Canberra Times Emyria Managing Director, Dr Michael Winlo, wrote an opinion editorial in March 2021 for The Canberra Times and other selected media outlets too. In this, he examined the opportunity for supported, learning-based healthcare models to test the merits of psychedelic substances in treating mental health conditions. We are proud of our data- backed care model at Emyria and Emerald Clinics – which is designed to learn from every single patient and open doors to novel treatments. 25 OP I NIO N MARCH 20 2021 Psychedelic substances represent a chance to alleviate Australia’s mental health crisis Dr Michael Winlo On February 3, the Therapeutic Goods Administration published an interim decision not to reschedule psychedelic substances, including MDMA and psilocybin, to schedule 8 of the poisons standard. A final decision is expected from the TGA in April. A rescheduling, if permitted, would mean these substances could be registered as future medicines and would have also improved patient access under special access schemes. This would therefore allow for more safe, controlled research into the efficacy of psychedelics as a mental health treatment in Australia. The facts are that Australia is facing a mental health crisis that is showing no signs of abating. According to a June Productivity Commission report, 1 in 5 Australian adults have a chronic mental illness. The cost of mental illness to the Australian economy is staggering, estimated at $220 billion a year. At Emerald Clinics, a large proportion of patients referred to us for cannabinoid-based medicines have mental health concerns such as major depression, anxiety disorders and addiction. Many of these conditions are only exacerbated by the past and ongoing effects of the COVID-19 pandemic. What is clear is that new avenues to alleviating the crisis are crucial, both for the wellbeing of our community and the strength of our economy. In considering the submission, the TGA raised concerns about the level of clinical evidence to maintain patient safety. While the TGA’s caution is reasonable, the level of research conducted in highly-respected institutions like Johns Hopkins, Yale, Imperial College and other major European and North American universities has provided enough promising efficacy data to move forward in Australia. Studies have shown that psilocybin, when used properly, seems to have minimal adverse side effects, especially in contrast to antidepressants. And it seems to be effective, with 84 per cent of participants in a John Hopkins study of 1993 individuals reporting psychological benefits. It is being used by medical practitioners as part of expanded Access Schemes in the US, Switzerland, Israel and on a case- by-case basis in Canada. MDMA in a controlled clinical setting has also shown limited misuse, abuse or overdose potential internationally and has low toxicity at therapeutic doses. Phase 2 and interim phase 3 results suggest it can be effective in conjunction with psychotherapy for PTSD. At Emyria, in conjunction with Mind Medicine Australia, we are further working to alleviate the TGA’s concerns and provide the platform to allow patients with major mental health concerns access to these promising new treatments while also support research through the development of an evidence-generating clinical model for psilocybin and MDMA. The model employs controlled and evidenced-based study protocols, detailed schedules of licensed and validated assessments of clinical and patient-reported outcomes, digital technology, training manuals and data governance frameworks to ensure thorough, quality, best- practice data gathering. In addition, it employs appropriately credentialed clinicians to ensure with utmost patient safety at all times, clinical-trial grade data management systems and processes and a fit-for-purpose facility with close proximity to psychologists, psychiatrists and physicians. We believe this model will provide much of the infrastructure the TGA believed was lacking in its initial assessment - and strongly believe that by using the principles of a learning health system, we can protect public safety and accelerate the registration and care model of psilocybin, while alleviating the suffering of so many Australians. 26 EMERAL D CI N ICS FEATU RE An intelligent model for care and drug design 2-98 years age range of patients 56% female patients 53% patients presenting with symptoms of moderate to severe depression 35% patients experiencing an adverse event 0-197mg range of THC prescribed doses are carefully titrated for each patient which gives Emyria unique dose response insights 27 Our data is the brain of our Company. With millions of unique data points, we are empowered to explore the potential of novel treatments for unmet needs. An intelligent model for informing care - and drug development too. 44 unique primary indications 54% patients presenting with symptoms of moderate to severe anxiety 7.12 average concomitant medications per patient at initial risk 0-600mg range of CBD prescribed doses are carefully titrated for each patient which gives Emyria unique dose response insights 28 E MYRIA AN NUAL REPORT 2021 Directors’ report 29 The Company appointed an expert neuropharmacologist for its MDMA-analogue development programme and engaged with Calvert Labs for preclinical CBD studies on its novel synthetic cannabinoid platform. The Company appointed Mary-Ann Rennie as the Corporate Operations Lead effective 19 July 2021. The following KMPs changed their role: Patrizia Washer resigned as Research Manager (effective 30 July 2021) but remains with the Company in an advisory capacity; Adam James resigned as Chief Operating Officer (effective 31 July 2021) but remains on a consulting basis in a Business Development Manager capacity; and Su-Mei Sain resigned as Chief Financial Officer (effective 9 July 2021). Future development, prospects and business strategy The Group will focus on developing its business which combines the treatment of patients, the capture of high-quality clinical data to transform the way novel therapies are understood and researched and drug development of its key projects leading towards registration. The Group will also combine its data with other health records and published information to generate actionable evidence for physicians, drug developers, research groups and government departments. Dividend paid and recommended No dividends have been declared, provided for or paid in respect of the financial year ended 30 June 2021 (30 June 2020: nil). The directors present their report for Emyria Limited (“Emyria” or “the Company”) and its subsidiaries (“the Group”) for the financial year ended 30 June 2021. Directors The names of the directors in office at any time during or since the end of the year ended are: Dr Stewart Washer Executive Chairman Dr Michael Winlo Managing Director Professor Alistair Vickery Executive Medical Director Mr Matthew Callahan Non-Executive Director Professor Sir John Tooke Non-Executive Director Review of operations The Group continued to provide a high level of care for its patients through Emyria’s specialist clinics whilst gathering Real-World-Evidence (“RWE”) insights for unregistered treatments such as cannabinoid-based medicines and drug development. To enhance the Group’s digital health platform, Emyria has invested in monitoring technology to enable remote data capture from its patients. See pages 14-19 for the complete Review of Operations. Events after reporting date In August 2021, Emyria entered into an exclusive agreement with University of Western Australia to develop a drug discovery pipeline of novel psychedelic therapies. Emyria and Cann Group mutually agreed to terminate the collaboration agreement entered into in March 2021 and Emyria entered into a CBD agreement with Altasciences to deliver a range of novel, synthetic cannabinoid-based medicines for Emyria’s Australian and US drug registration program. 30 Directors’ report Information on Directors and Company Secretary Dr Stewart Washer Executive Chairman Appointed 19 February 2018 Dr Michael Winlo Managing Director Appointed 8 November 2019 Michael has a Bachelor of Medicine and Bachelor of Surgery with Honours from the University of Western Australia as well as a Master of Business Administration from Stanford University. Prior to Emyria, Michael was CEO at Linear Clinical Research Ltd (Linear) until October 2019 –a company providing clinical trial services for US- and Asia-based biotech companies. Linear was the first site in Australia and one of only a few in the world to successfully adopt electronic data capture technology. Under Michael’s leadership, Linear’s revenues grew over 300% in just over three years (to over $23 million per year). Michael retains a Directorship at Linear. Prior to Linear, Michael was Health Lead at Palantir Technologies – a Big Data company based in Silicon Valley California. Other current directorships of a public listed company None Former directorships in last three years of a public listed company None Interest in shares and options Shares Options nil 7,500,000 Stewart has 25 years of CEO and board experience in medical and agri-food biotech companies. He is director of Botanix Pharmaceuticals Ltd (ASX: BOT), clinical studies on CBD for antimicrobial and topical applications and Founding Chairman and current Director of Cynata Therapeutics Ltd (ASX:CYP) stem cell therapies. Stewart has held a number of Board positions in the past, including Chairman of Hatchtech Pty Ltd that was sold in 2015 for A$279m and was a director of iCeutica that was sold to a US Pharma. He was also a Senator with Murdoch University and was a Director of AusBiotech Ltd. Other current directorships of a public listed company Cynata Therapeutics Limited (ASX: CYP) Appointed as Director on 1 August 2013 Orthocell Limited (ASX: OCC) Appointed as Chairman on 7 April 2014 Botanix Pharmaceuticals Limited (ASX: BOT) Appointed as Director on 21 February 2019 Former directorships in last three years of a public listed company Zelira Therapeutics Limited (ASX: ZLD) From 17 November 2016 to 2 December 2019 Interest in shares and options Shares 49,325,599 (29,725,599 shares are in the control of Dr Stewart Washer and Dr Patrizia Washer) Options 1,500,000 (options held are in the control of Dr Stewart Washer and Dr Patrizia Washer) EMYRIA ANNUAL REPORT 2021 31 Professor Alistair Vickery Executive Medical Director Appointed 12 November 2018 Mr Matthew Callahan Non -Executive Director Appointed 19 March 2018 Alistair is the medical director of Emyria and has a wealth of expertise in clinical practice, health service management, clinical and educational research and board director skills. He is adjunct Clinical Professor of Primary Health Care at the University of Western Australia and Notre Dame University and an active specialist general practitioner. He is the clinical lead of the research group CHASM (The Collaborative for Health Care Analysis and Statistical Modelling) - providing high-level analysis and statistical modelling to inform clinical service planning and service evaluation. Alistair is Board Chair of Black Swan Health, one of the largest NFP primary health care service providers in Western Australia, and a Fellow of the Australasian College of Health Service Management and an AICD graduate. Other current directorships of a public listed Group None Former directorships in last three years of a public listed Group None Interest in shares and options Matthew is an experienced life sciences executive based in Philadelphia. He is a founding director of Emyria and has been the founding CEO or Executive Director of a number of pharmaceutical and health tech companies including Botanix Pharmaceuticals Ltd (ASX: BOT), iCeutica Inc, Churchill Pharma Inc. Dimerix Biosciences (ASX: DXB) and Orthocell (ASX: OCC). He has led the development of four pharmaceutical products that have received FDA approval and he has more than 25 years legal, IP and investment management experience. Mr Callahan has worked as an investment director for two venture capital firms investing in life sciences, technology and other sectors, and was general manager of Australian listed technology and licensing company ipernica (now Nearmap ASX: NEA), where he was responsible for the licensing programs that generated more than $120M in revenue. Other current directorships of a public listed Group Botanix Pharmaceuticals Limited (ASX: BOT) Appointed as a director 1 July 2016, resigned 23 August 2019 and re-appointed as Director on 10 February 2020 Shares Options 128,000 4,000,000 Orthocell Limited (ASX: OCC) Appointed 30 May 2006, resigned 23 August 2019 and re-appointed as Director on 10 February 2020 Former directorships in last three years of a public listed Group As noted above Interest in shares and options Shares Options 19,600,000 1,500,000 Mr Simon Robertson Company Secretary Simon gained a Bachelor of Business from Curtin University in Western Australia and a Master of Applied Finance from Macquarie University in New South Wales. He is a member of the Institute of Chartered Accountants and Chartered Secretaries Australia. Simon currently holds the position of company secretary for a number of publicly listed companies and has experience in corporate finance, accounting and administration, capital raising and ASX compliance and regulatory requirements. Principal activities During the financial year ended 30 June 2021, the Group continued to provide a high level of care for its patients through Emyria’s specialist clinics whilst gathering Real-World-Evidence (“RWE”) insights in relation to novel therapies such as medicinal cannabinoids and drug development. 32 Directors’ report Professor Sir John Tooke Non-Executive Director Appointed 10 February 2020 Sir John is Executive Chairman of Academic Health Solutions, a start-up Group offering expert advice to clients internationally on medical research and innovation strategy and health service transformation. He is Senior Independent Director at BUPA Chile and was until 2019 non-executive director of the BUPA main Board and the Chair of the Medical Advisory Council. He has recently been appointed as non- executive director of the Northern Health Science Alliance in the UK. He is the Chair of Collaboration for the Advancement of Sustainable Medical Innovation (CASMI) UCL and Chaired the Oversight Group for the Academy of Medical Sciences project ‘How we best use scientific evidence to judge the benefits and harms of medicines’. He also served as an Independent Review Board Member for Google DeepMind Health (UK). Sir John was past Head of the School of Life and Medical Sciences at University College London (UCL) as Vice Provost (Health) and Academic Director of UCL Partners from 2010 - 2015. He is the Past President of the Academy of Medical Sciences in the UK. Sir John is a clinician scientist with 30 years’ experience as a consultant physician specialising in diabetes, endocrinology, vascular medicine and internal medicine with broad research experience (basic biomedical, experimental medicine, and applied health research including improvement science) recognised through Fellowship of the Academy of Medical Sciences. He held a Board position at the Francis Crick Institute (2011 -2015) and was a Member of the Council for Science & Technology (2011-2015) reporting to the Prime Minister (UK). Other current directorships of a public listed company None Former directorships in last three years of a public listed company None Interest in shares and options Shares Options nil 1,500,000 EMYRIA ANNUAL REPORT 2021 33 Meeting of Directors During the financial year ended 30 June 2021, the following table outlines the number of meetings held: Stewart Washer, Chairman Matthew Callahan, Non-Executive Director Michael Winlo, Managing Director Alistair Vickery, Executive Director Sir John Tooke, Non-Executive Director A Number of meetings attended Full meetings of directors A B Risk Committee Meetings A B 9 9 9 9 9 9 9 9 9 9 • 4 • 4 4 • 4 • 4 4 B Number of meetings held during the time the director held office or was a member of the committee during the year • Not a member of the relevant committee At the date of this report, the Group has the following options on issue. Number 11,250,000 1,000,000 3,500,000 600,000 1,000,000 1,000,000 3,500,000 8,500,000 500,000 6,000,000 4,705,883 1,500,000 775,000 5,000,000 14,285,715 63,116,598 Exercise Price Grant Date Expiry Date $0.450 $0.450 $0.450 $0.450 $0.450 $0.450 $0.114 $0.114 $0.114 $0.200 $0.200 $0.268 $0.256 $0.350 $0.350 13 June 2019 13 June 2023 19 June 2019 13 June 2023 10 July 2019 13 June 2023 26 September 2019 26 September 2023 24 October 2019 13 June 2023 11 November 2019 13 June 2023 24 September 2020 13 November 2024 13 November 2020 13 November 2024 22 December 2020 22 December 2023 22 December 2020 22 December 2022 22 December 2020 22 December 2022 20 February 2021 20 February 2024 18 March 2021 18 March 2024 28 April 2021 28 April 2023 28 April 2021 28 April 2024 34 Directors’ report No shares were issued during or since the end of the year as a result of the exercise of an option over unissued shares of interest. For details of options issued to directors and other key management personnel, please refer to the Remuneration Report. The principles adopted have been approved by the Board and have been set out in this Remuneration Report. This audited Remuneration Report is set out under the following main headings: 1. Principles used to determine the nature and amount of remuneration Remuneration report (audited) This Remuneration Report, which has been audited, outlines the Key Management Personnel (as defined in AASB 124 Related Party Disclosures) (“KMP”) remuneration arrangements for the Group, in accordance with the requirements of the section 308 (3c) of the Corporations Act 2001 and its Regulations. The KMP covered in this remuneration report are: Dr Stewart Washer Executive Chairman Dr Michael Winlo Managing Director Professor Alistair Vickery Executive Medical Director Mr Matthew Callahan Non-Executive Director Professor Sir John Tooke Non-Executive Director Patrizia Washer Research Manager (resigned effective 30 July 2021) Adam James Chief Operating Officer (role adjusted effective 31 July 2021) Su-Mei Sain Chief Financial Officer (resigned effective 9 July 2021) 2. Details of remuneration 3. Service agreements 4. Share-based compensation The information provided under headings 1 to 4 above includes remuneration disclosures that are required under Accounting Standard AASB 124, Related Party Disclosures. 1. Principles used to determine the nature and amount of remuneration The objective of the Group’s executive reward framework is to ensure reward for performance is competitive and appropriate for the results delivered. The framework which has been set out in detail under the remuneration structure in this Remuneration Report aligns executive reward with achievement of strategic objectives and the creation of value for shareholders, and conforms to markets best practice for delivery of reward. The Board ensures that executive reward satisfies the following key criteria for good reward governance practices: (i) competitiveness and reasonableness; (ii) aligns shareholders and executive interests; (iii) performance based and aligned to the successful achievement of strategic and tactical business objectives; and (iv) transparency. Executive Directors Remuneration to Executive Directors reflects the demands which are made on, and the responsibilities of, the Executive Directors. Executive Directors’ remuneration is reviewed to ensure it is appropriate and in line with the market. Other than notice periods, there are no other benefits paid to Executive Directors other than superannuation guarantee amounts as required. EMYRIA ANNUAL REPORT 2021 35 The executive remuneration and reward framework has three components: (i) base pay; (ii) share-based payments; and (iii) other remuneration such as superannuation and long service leave. The combination of these comprises the Executive Director’s total remuneration. Fixed remuneration, consisting of base salary and superannuation will be reviewed annually by the board, based on individual contribution to corporate performance and the overall relative position of the Group to its market peers. Non - Executive Directors Remuneration to Non-Executive Directors reflects the demands which are made on, and the responsibilities of, the Non-Executive Directors. The maximum aggregate for remuneration of Non-Executive Directors is set by shareholders and is currently $500,000. For the year ended 30 June 2021, exclusive of superannuation guarantee the annual cash remuneration paid to Non- Executive Directors was $50,000 per annum each. Short-term incentives The Company’s approach in regard to the use of short- term cash incentives will be assessed by the board on an ongoing basis as the Company evolves. Long-term incentives To align the board and management with shareholder’s interests and with market practices of peer companies and to provide a competitive total remuneration package, the Board introduced a long-term incentive (“LTI”) plan to motivate and reward Executives and Non-Executive Directors. The LTI is provided as options over ordinary shares of the Group under the rules of the Securities Incentive Plan. During the year ended 30 June 2021, there were 4,000,000 options issued to the Managing Director, 2,000,000 options issued to the Executive Medical Director, 2,500,000 options issued to each Non-Executive Directors, 1,500,000 options issued to the Chief Operating Officer and 1,000,000 options issued to the Chief Financial Officer. Group performance, shareholder wealth and directors’ and executives’ remuneration As an early-stage drug development company, the Board does not consider the operating loss after tax as one of the performance indicators when implementing an incentive-based remuneration policy. The board considers that identification and securing of new business growth opportunities, the securing of funding arrangements and responsible management of cash resources and the Group’s other assets as more appropriate performance indicators to assess the performance of management. No relationship exists between shareholder wealth, director and executive remuneration and Group performance as it is an early-stage drug development company. The table below shows the losses and earnings per share of the Group for the current and last two financial years. Net loss (4,906,234) (5,238,040) (2,682,928) Share price at year end (cents) Loss per share (cents) 18.50 (2.24) 4.80 (3.04) N/A* (2.06) 2021 2020 2019 * The Company was admitted to the ASX on 10 February 2020 36 Directors’ report 2. Details of remuneration Year ended 30 June 2021 The amount of remuneration paid and entitlements owed to KMP is set out below. 2021 Cash remuneration and entitlements Cash remuneration Salary and other fees $ 200,000 350,000 368,992 50,000 54,620 Directors S Washer M Winlo A Vickery* M Callahan Sir J Tooke** Other Key Management Personnel A James S Sain*** P Washer 200,000 147,246 226,897 1,597,755 Post– employment benefits Annual leave entitlement movement Total cash payments and entitlements Bonus $ - - - - - - - - - $ - 25,000 6,250 - - 19,000 13,919 21,038 85,207 $ - 1,344 (4,040) - - (13,848) (4,441) - $ 200,000 376,344 371,202 50,000 54,620 205,152 156,724 247,935 (20,985) 1,661,977 * A Vickery received exemption on superannuation and received the balance of his superannuation contribution as an additional payment. ** In addition to Sir Tooke’s director’s fee, he also received a consultancy fee of $4,620 during the year. *** During the year, S Sain reduced hours and was paid on a pro-rata basis. EMYRIA ANNUAL REPORT 2021 37 Year ended 30 June 2020 The amount of remuneration paid and entitlements owed to KMP is set out below. 2020 Cash remuneration and entitlements Cash remuneration Salary and other fees $ 259,944 361,693 354,786 50,000 124,248 Directors S Washer M Winlo* A Vickery* M Callahan Sir J Tooke*** Other Key Management Personnel A James S Sain** P Washer**** 197,256 118,904 267,217 Bonus $ - 50,000 100,000 - - - - - 1,734,048 150,000 Post– employment benefits Annual leave entitlement movement Total cash payments and entitlements $ - 25,000 16,625 - - 18,842 11,357 25,000 96,824 $ - 26,624 24,231 - - 12,307 8,723 - $ 259,944 463,317 495,642 50,000 124,248 228,405 138,984 292,217 71,885 2,052,757 * During the financial year ended 30 June 2020 and in accordance with their executive agreements, Dr Winlo and Professor Vickery received a cash bonus in relation to the successful listing of the Company on 12 February 2020. ** Mrs Sain was appointed Chief Financial Officer on 30 September 2019 *** In addition to Professor Tooke’s director’s fee, he also received a consultancy fee of $105,082 during the year. **** Dr P Washer was Research Director until 28 October 2019 38 Directors’ report Year ended 30 June 2021 2021 Total remuneration Total remuneration Total cash remuneration and entitlements Options expensed Directors S Washer M Winlo A Vickery M Callahan Sir J Tooke $ 200,000 376,344 371,202 50,000 54,620 Other Key Management Personnel A James S Sain P Washer 205,152 156,724 247,935 1,661,977 Year ended 30 June 2020 2020 Total remuneration $ - 94,200 41,844 31,058 20,705 40,469 41,115 325 269,716 Total remuneration Total cash remuneration and entitlements Options expensed Directors S Washer M Winlo A Vickery M Callahan Sir J Tooke $ 259,944 463,317 495,642 50,000 124,248 Other Key Management Personnel A James S Sain P Washer 228,405 138,984 292,217 2,052,757 $ - 42,624 528 - - 396 27,073 396 71,017 Total $ 200,000 470,544 413,046 81,058 75,325 245,621 197,839 248,260 1,931,693 Total $ 259,944 505,941 496,170 50,000 124,248 228,801 166,057 292,613 2,123,774 LTI % of remuneration $ 0% 20.0% 10.1% 38.3% 27.5% 16.5% 20.8% 0.1% LTI % of remuneration $ 0% 8.4% 0.1% 0% 0% 0.2% 16.3% 0.1% There were no non-monetary benefits paid to the Directors or KMP for the year ended 30 June 2021. Other than those disclosed above, there were no transactions with related parties to the KMP for the year ended 30 June 2021. EMYRIA ANNUAL REPORT 2021 39 3. Service agreements For the year ended 30 June 2021, the following service agreements were in place with the Directors and KMP of Emyria: On 18 March 2019, a Senior Executive Employment Agreement was entered into between the Company and Medical Director Professor Alistair Vickery. Under the terms of the Agreement: On 27 July 2018, a Consultancy Agreement was entered into between the Company and Biologica Ventures Pty Ltd nominating Dr Stewart Washer as Executive Chairman. Under the terms of the Agreement: • On 2 December 2019, Dr Washer’s Agreement was amended to reflect that his annual consultancy fee to be $200,000 per annum commencing 12 February 2020. • Dr Washer’s fees were paid to Biologica Ventures Pty Ltd. • Professor Vickery was paid a base salary of $350,000 per annum plus statutory superannuation. • Under the general termination of employment provision, the Company may terminate the Agreement by giving Professor Vickery twenty-four months’ notice or payment in lieu of notice. • Under the general termination of employment provision, Professor Vickery may terminate the Agreement by giving the Company twelve months’ notice or payment in lieu of notice. • Under the general termination of consultancy provision, the Company may terminate the Agreement by giving Dr Washer six months’ notice or payment in lieu of notice. • The Company may terminate the Agreement at any time without notice if serious misconduct has occurred. On termination with cause, the Executive is not entitled to any payment. • Under the general termination of consultancy provision, Dr Washer may terminate the Agreement by giving the Company three months’ notice or payment in lieu of notice. • The Company may terminate the Agreement at any time without notice if serious misconduct has occurred. On termination with cause, the Executive is not entitled to any payment. On 3 May 2019, a Chief Executive Employment Agreement (changed to Managing Director effective 26 November 2019) was entered into between the Company and Managing Director Dr Michael Winlo. Under the terms of the Agreement: • Dr Winlo was paid a base salary of $350,000 per annum plus statutory superannuation. • Under the general termination of employment provision, the Company may terminate the Agreement by giving Dr Winlo three months’ notice or payment in lieu of notice. • Under the general termination of employment provision, Dr Winlo may terminate the Agreement by giving the Company six months’ notice or payment in lieu of notice. • The Company may terminate the Agreement at any time without notice if serious misconduct has occurred. On termination with cause, the Executive is not entitled to any payment. On 1 July 2018, a Consultancy Agreement was entered into between the Company and Research Director Dr Patrizia Washer. Dr Washer resigned as a director 28 October 2019 and remained as Research Manager on a consulting basis. Under the terms of the Agreement: • Dr Washer was paid a consultancy fee of a minimum of $3,000 per week for 2 days week inclusive of statutory superannuation. • Under the general termination of consultancy provision, the Company could terminate the Agreement by giving Dr Washer one month’s notice or payment in lieu of notice. • Under the general termination of consultancy provision, Dr Washer could terminate the Agreement by giving the Company one months’ notice or payment in lieu of notice. • The Group could terminate the Agreement at any time without notice if serious misconduct has occurred. On termination with cause, the Consultant will be paid up to the date of termination. • Dr Washer resigned as a consultant effective 30 July 2021 and remains as a consultant in an advisory capacity. 40 Directors’ report On 14 November 2019, an Agreement was entered into between the Company and Mr Matthew Callahan for his on-going appointment as Non-Executive Director. Under the terms of the Agreement: • Mr Callahan was paid a remuneration package of $50,000 per annum base salary. • Termination of this Agreement will be upon the date provided by either party. There is no notice period applicable to this Agreement. • Mr Callahan has a consultancy agreement with the Group that commenced on 4 November 2019 for a period of three years. Under the terms of the consultancy agreement: • The consultancy services include an hourly rate of USD $300 per hour and it will be subject to review on an annual basis. • Under the general termination of consultancy provision, the Group may terminate the Agreement by giving Mr Callahan six month’s notice or payment in lieu of notice. • Under the general termination of consultancy provision, Mr Callahan may terminate the Agreement by giving the Group six months’ notice or payment in lieu of notice. • The Group may terminate the Agreement at any time without notice if serious misconduct has occurred. On termination with cause, the Consultant will be paid up to the date of termination. On 4 November 2019, an Agreement was entered into between the Company and Professor Sir John Tooke as Non-Executive Director. Under the terms of the Agreement: • Appointed as Non-Executive Director effective from 12 February 2020. • • • • Professor Tooke was paid a remuneration package of $50,000 per annum base salary. Termination of this Agreement will be upon the date provided by either party. There is no notice period applicable to this Agreement. Professor Tooke has a consultancy agreement with the Group that commenced on 1 April 2020 for a period of three years. Under the terms of the Agreement: The consultancy services include a rate of GBP $2,500 per day. • Under the general termination of consultancy provision, the Group may terminate the Agreement by giving Professor Tooke one month’s notice or payment in lieu of notice. • Under the general termination of consultancy provision, Professor Tooke may terminate the Agreement by giving the Group one months’ notice or payment in lieu of notice. • The Group may terminate the Agreement at any time without notice if serious misconduct has occurred. On termination with cause, the Consultant will be paid up to the date of termination. On 1 July 2018, the Company entered into an Executive Services Agreement (amended 22 November 2019) with Mr Adam James. Under the terms of the Agreement: • Mr James was appointed in the capacity of Chief Operating Officer and paid a remuneration package of $200,000 per annum base salary plus statutory superannuation. • • • The Group or Mr James could terminate the contract at any time by giving the other party six months’ notice or payment in lieu of notice. The Group could terminate the Agreement at any time without notice if serious misconduct has occurred. On termination with cause, Mr James is not entitled to any payment. If there are monies owed by Mr James to the Group, the Group is entitled to offset this against Mr James’ termination payment. • Mr James resigned as COO (effective 31 July 2021) and is retained as Business Development Manager on a consulting basis. On 30 September 2019, the Company entered into an employment contract (amended 3 February 2020) with Mrs Su-Mei Sain. Under the terms of the Agreement: • Mrs Sain was appointed in the capacity of Chief Financial Officer and paid a remuneration package of $190,000 per annum base salary plus statutory superannuation. • • The Group or Mrs Sain could terminate the contract at any time by giving the other party three months’ notice or payment in lieu of notice. The Group could terminate the Agreement at any time without notice if serious misconduct has occurred. On termination with cause, Mrs Sain is not entitled to any payment. • Mrs Sain resigned from the Group effective 9 July 2021. EMYRIA ANNUAL REPORT 2021 41 4. Share-based compensation Option holdings The numbers of options in the Group held during the year ended by each KMP of Emyria, including their related parties, are set out below: Balance at the start of the year Granted during the year Expired during the year Other changes Balance at the end of the year 2021 Directors S Washer M Winlo A Vickery M Callahan Sir J Tooke - - 3,500,000 4,000,000 2,000,000 2,000,000 - 1,500,000 500,000 1,000,000 6,000,000 8,500,000 Other Key Management Personnel A James S Sain P Washer Total 1,500,000 1,500,000 1,000,000 1,000,000 1,500,000 - 10,000,000 11,000,000 - - - - - - - - - - - - - - - - - - - - - 7,500,000 4,000,000 1,500,000 1,500,000 14,500,000 3,000,000 2,000,000 1,500,000 21,000,000 As at 30 June 2021, the number of options that have vested and exercisable were 12,166,667 and the number of options yet to vest and un-exercisable were 8,833,333. The option terms and conditions of each grant of options over ordinary shares affecting remuneration of Directors and other KMP in the year ended or future reporting years are as follows: Options issued Employee Securities Incentive Plan Employee Securities Incentive Plan Employee Securities Incentive Plan Employee Securities Incentive Plan Employee Securities Incentive Plan Grant date Expiry date Exercise price $ Fair value per option $ Vested % * 13 Jun 2019 13 Jun 2023 0.45 0.00756 100% 10 Jul 2019 13 Jun 2023 11 Nov 2019 13 Jun 2023 24 Sep 2020 13 Nov 2024 13 Nov 2020 13 Nov 2024 0.45 0.45 0.114 0.114 0.0105 100% 0.0497 0.037 0.032 94% 33% 33% * The vesting conditions are: • One third immediately on issue; • One third one year from date of issue subject to continued employment or service and; • One third two years from date of issue subject to continued employment or service. 42 Directors’ report The options issued to the during the financial year 30 June 2021 were valued using a Black-Scholes model and were priced as follows: Series 8 Series 9 Grant date share price 0.083 Exercise price Expected volatility Option life Dividend yield Interest rate 0.114 70% 4 years 0.00% 0.3% 0.076 0.114 70% 4 years 0.00% 0.3% Shareholdings The number of shares in the Group held during the year ended by each KMP of Emyria, including their related parties, are set out below: 2021 Directors S Washer* M Winlo A Vickery M Callahan J Tooke Other Key Management Personnel A James S Sain P Washer* Balance at the start of the year Other changes during the year Balance at the end of the year 48,550,499 - - 19,600,000 - 1,960,000 20,000 - 70,130,499 775,090 - 128,000 - - - - - 903,090 49,325,589 - 128,000 19,600,000 - 1,960,000 20,000 - 71,033,589 * Dr Stewart Washer and Dr Patrizia Washer both control 28,950,499 of Emyria shares. There were no shares granted to KMP’s during the reporting year as remuneration. EMYRIA ANNUAL REPORT 2021 Use of remuneration consultants No remuneration consultants were engaged or used for the Group during the year ended 30 June 2021. Remuneration voting and comments made at the Company’s Annual General Meeting At the AGM held in 2020, the Company received 100% “FOR” votes on its Remuneration Report for the 2020 financial year. The Company did not receive any specific feedback at the AGM on its remuneration practices. Share trading policy The trading of shares issued to participants under any of the Group’s employee equity plans is subject to, and conditional upon, compliance with the Group’s security trading policy as per the Group’s Corporate Governance Policy. Directors and executives are prohibited from entering into any hedging arrangements over unvested options under the Group’s employee securities incentive plan. This concludes the Remuneration Report, which has been audited. 43 Indemnifying officers During the financial year, the Company has paid a premium of $73,944 excluding GST (2020: $37,186) to insure the Directors and secretary of the Company. The liabilities insured are legal costs that may be incurred in defending civil or criminal proceedings that may be brought against the officers in their capacity as officers of the Company, and any other payments arising from liabilities incurred by the officers in connection with such proceedings. This does not include such liabilities that arise from conduct involving a wilful breach of duty by the officers or the improper use by the officers of their position or of information to gain advantage for themselves or someone else or to cause detriment to the Company. It is not possible to apportion the premium between amounts relating to the insurance against legal costs and those relating to other liabilities. Proceedings on behalf of the Group No person has applied for leave of Court to bring proceedings on behalf of the Group or intervene in any proceedings to which the Group is a party for the purpose of taking responsibility on behalf of the Group for all or any part of those proceedings. The Group was not a party to any such proceedings during the year. Auditor Stantons International was appointed as auditors for the Group in office in accordance with section 327 of the Corporations Act 2001. Audit Services During the year ended 30 June 2021 $51,074 (2020: $36,679) was paid or is payable for audit services provided by the auditors. There were no non-audit services performed during the financial year. Auditor’s independence declaration The auditor’s independence declaration as required under section 307C of the Corporations Act 2001 is included on page 53 of the financial report. Signed in accordance with a resolution of the Board of Directors: Dr Michael Winlo Managing Director 31 August 2021 44 E MYRIA AN NUAL REPORT 2021 Financial report 45 Consolidated Statement of Profit or Loss and Other Comprehensive Income. For the year ended 30 June 2021 Revenue Sales revenue Operating costs Gross loss Other revenue Interest and other income Research and Development grant received Total other revenue Expenses Research and Development expenses Employee wages and director fees Corporate compliance costs Finance costs Share based payments Other expenses Depreciation and amortisation expense Fixed assets write off Intangible assets written off Total expenses Loss before income tax expense Income tax Notes 2(a) 2(a) 12 2(b) 2(c) 7 8 3 Group 2021 $ Group 2020 $ 1,975,909 (2,264,272) (288,363) 23,148 954,180 977,328 (2,618,968) (951,397) (416,753) (66,851) (429,558) (660,923) (344,875) (105,874) - (5,595,199) (4,906,234) - 1,013,452 (1,938,477) (925,025) 25,046 468,177 493,223 (1,505,165) (1,478,501) (624,200) (59,544) (79,328) (635,442) (383,481) - (40,577) (4,806,238) (5,238,040) - Loss after income tax for the year (4,906,234) (5,238,040) Other Comprehensive Income for the year: Items that may be reclassified subsequently to profit or loss Other Comprehensive income for the year, net of tax - - - - Total comprehensive loss for the year (4,906,234) (5,238,040) Basic and diluted loss per share (cents) 15 (2.24) (3.04) The accompanying notes form part of these financial statements. 46 Financial report Consolidated Statement of Financial Position. As at 30 June 2021 Assets Current assets Cash and cash equivalents Trade and other receivables Prepayments Total current assets Non-current assets Restricted cash Right-of-use assets Plant and equipment Intangible assets Total non-current assets Total assets Liabilties Current liabilities Trade and other payables Borrowings Provisions Lease liabilities Total current liabilities Non-current liabilities Provisions Lease liabilities Total non-current liabilities Total liabilities Net assets Equity Contributed equity Reserves Accumulated losses Total equity Notes Group 2021 $ Group 2020 $ 4 5 6 7 8 9 9 10 9 10 9 11 13 6,528,926 273,404 81,600 6,883,930 161,864 880,589 399,546 733,630 2,175,629 9,059,559 678,523 - 156,120 197,630 3,686,333 121,615 31,433 3,839,381 156,558 323,390 598,305 147,310 1,225,563 5,064,944 461,124 247,154 142,088 152,689 1,032,273 1,003,055 97,000 752,069 849,069 1,881,342 7,178,217 19,310,804 826,746 (12,959,333) 7,178,217 68,000 210,972 278,972 1,282,027 3,782,917 11,751,953 84,063 (8,053,099) 3,782,917 The accompanying notes form part of these financial statements. EMYRIA ANNUAL REPORT 2021 47 Accumulated Losses $ Total equity $ (8,053,099) 3,782,917 (4,906,234) (4,906,234) - - (4,906,234) (4,906,234) - - - (12,959,333) 8,400,000 (841,149) 742,683 7,178,217 Accumulated Losses $ Total equity $ (2,747,268) 499,539 (5,238,040) (5,238,040) - - (5,238,040) (5,238,040) (67,791) (67,791) - - - - - 6,500,000 (742,740) 2,930,666 (178,045) 79,328 (8,053,099) 3,782,917 Contributed equity $ 11,751,953 Reserves $ 84,063 Consolidated Statement of Changes in Equity. For the year ended 30 June 2021 Group Balance at 1 July 2020 (Loss) after income tax for the year Other comprehensive income for the year, net of tax Total comprehensive loss - - - Proceeds from issued capital 8,400,000 Transaction costs from issued capital Issue of options (841,149) - Balance at 30 June 2021 19,310,804 Balance at 1 July 2019 (Loss) after income tax for the year Other comprehensive income for the year, net of tax Total Comprehensive loss Adjustment on initial application of AASB 16 Contributed equity $ 2,872,738 - - - - Proceeds from issued capital 6,500,000 Transaction costs from issued capital Conversion of Convertible Notes to shares Transaction cost from conversion of Convertible Note Issue of options (742,740) (178,045) - Balance at 30 June 2020 11,751,953 3,300,000 (369,334) The accompanying notes form part of these financial statements. - - - - - 742,683 826,746 Reserves $ 374,069 - - - - - - - 79,328 84,063 48 Financial report Consolidated Statement of Cash Flows. For the year ended 30 June 2021 Cash flows from operating activities Receipts from customers Interest received Payments to suppliers and employees Interest and other finance costs paid R&D refund received Net cash (used in) operating activities Cash flows from investing activities Payments for plant and equipment Payments for intangible assets Net cash (used in) investing activities Cash flows from financing activities Proceeds from issue of shares Transaction costs paid from the issue of shares Proceeds from borrowings Repayment of borrowings Repayment of lease liabilities Net payments cash backed guarantees (restricted cash) Net cash provided by financing activities Net increase in cash and cash equivalents Cash and cash equivalents at the beginning of the year Notes 14 8 9 9 9 Group 2021 $ 2,007,188 22,979 (6,887,133) (34,533) 954,180 (3,937,319) (8,052) (653,334) (661,386) 8,400,000 (527,504) - (240,221) (185,671) (5,306) 7,441,298 2,842,593 3,686,333 Group 2020 $ 1,021,047 21,436 (5,937,031) (26,100) 468,177 (4,452,471) (201,806) - (201,806) 6,500,000 (742,740) 240,221 - (215,385) (50,300) 5,731,796 1,077,519 2,608,814 Cash and cash equivalents at the end of the year 4 6,528,926 3,686,333 The accompanying notes form part of these financial statements. EMYRIA ANNUAL REPORT 2021 49 Notes to the consolidated financial statements For the year ended 30 June 2021 Emyria Limited (“Emyria” or “the Company”) is a Company incorporated in Australia whose shares are publicly traded on the Australian Securities Exchange (“ASX”). The consolidated financial statements of the Group as at and for the year ended 30 June 2021 comprise the Company and its subsidiaries (together referred to as the “Group” or “consolidated entity” and individually as a “Group entity”). The separate financial statements of the parent entity, Emyria Limited, have not been presented with this financial report. Summary parent information has been included in note 17. through profit or loss, investment properties, certain classes of property, plant and equipment and derivative financial instruments. (ii) Critical accounting estimates The preparation of the financial statements requires the use of certain critical accounting estimates. It also requires management to exercise its judgement in the process of applying the consolidated entity’s accounting policies. The areas involving a higher degree of judgement or complexity, or areas where assumptions and estimates are significant to the financial statements, are disclosed in note 1.1(vi). Note 1: statement of significant accounting policies 1.1 Basis of Preparation The financial report is a general purpose financial report that has been prepared in accordance with Australian Accounting Standards, Australian Accounting Interpretations, other authoritative pronouncements of the Australian Accounting Standards Board (“AASB”) and the Corporations Act 2001. Australian Accounting Standards set out accounting policies that the AASB has concluded would result in a financial report containing relevant and reliable information about transactions, events and conditions to which they apply. The consolidated financial statements and notes also comply with International Financial Reporting Standards as issued by the International Accounting Standard Board (IASB). Material accounting policies adopted in the preparation of this financial report are presented below. They have been consistently applied unless otherwise stated. The Group is a for-profit entity for financial reporting purposes under Australian Accounting Standards. The consolidated financial statements have been prepared on a going concern basis which contemplates the continuity of normal business activities and the realisation of assets and the settlement of liabilities in the ordinary course of business. The financial statements are presented in Australian Dollars (“AUD”). (i) Historical cost convention The consolidated financial statements have been prepared under the historical cost convention, except for, where applicable, the revaluation of financial assets, financial assets and liabilities at fair value (iii) Operating segments Operating segments are presented using the ‘management approach’, where the information presented is on the same basis as the internal reports provided to the Chief Operating Decision Makers (‘CODM’). The CODM is responsible for the allocation of resources to operating segments and assessing their performance. (iv) Going Concern For the year ended 30 June 2021, COVID-19 has impacted the Group, mainly in relation to any implications on the current period financial performance and cash flows (particularly operating cash flows). As of 30 June 2021, the Group had net working capital surplus of $5,851,657 (2020: $2,836,326) and cash balance of $6,528,926 (2020: $3,686,333). The Group did not have any capital commitments of as of 30 June 2021. The Directors have prepared projected cash flow information for the twelve months from the date of approval of these financial statements taking into consideration the estimation of the continued business impacts of COVID-19. In response to the uncertainty arising from this, the Directors have considered severe but plausible downside forecast scenarios. These forecasts indicate that, taking account of reasonably possible downsides, the Group is expected to continue to operate, with headroom and within available cash levels. Key to the forecasts are relevant assumptions regarding the business, business model, any legal or regulatory restrictions and shareholder support, in particular: 50 Notes to the consolidated financial statements For the year ended 30 June 2021 • Details of the results of the key scenario modelling on the entity’s ability to meet its obligations over the forecast period. pandemic and, if certain conditions are met, account for those rent concessions as if they were not lease modifications. • Mitigating actions undertaken or planned by directors and group to manage and respond to cash flow uncertainties or potential risks of shortfall in financing and the implementation status and uncertainties that arise from them. The Directors are satisfied they will be able to raise additional funds as required and thus it is appropriate to prepare the financial statements on a going concern basis. Despite COVID-19 affecting socio-economic factors in Australia and worldwide, the Group’s clinic operations and collection of insights had not been drastically impacted. The Directors are confident that the operations of the Group will continue to grow with the assistance of raising additional funds. If necessary, the Group can delay research and development expenditures and Directors can also institute cost saving measures to further reduce corporate and administrative costs or explore other opportunities to sell data and/or its clinics. In the event that the Group is unable to obtain sufficient funding for ongoing operating and capital requirements, there is a material uncertainty that may cast significant doubt as to whether the Group will continue as a going concern and therefore proceed with realising its assets and discharging its liabilities in the normal course of business at the amounts stated in the financial report. The consolidated financial statements do not include any adjustment relating to the recoverability or classification of recorded asset amounts or to the amounts or classification of liabilities that may be necessary should the Group not be able to continue as a going concern. (v) New and amended standards adopted by the Group The Group has considered the implications of new and amended Accounting Standards which have become applicable for the current financial reporting period. Initial adoption of AASB 2020-04: COVID-19-related rent concessions Initial adoption of AASB 2018-6: Amendments to Australian accounting standards – definition of abusiness AASB 2018-6 amends and narrows the definition of a business specified in AASB 3: Business Combinations, simplifying the determination of whether a transaction should be accounted for as a business combination or an asset acquisition. Entities may also perform a calculation and elect to treat certain acquisitions as acquisitions of assets. Initial adoption of AASB 2018-7: Amendments to Australian accounting standards – definition of material This amendment principally amends AASB 101 and AASB 108 by refining the definition of material by improving the wording and aligning the definition across the standards issued by the AASB. (vi) New and amended standards adopted by the entity Initial adoption of AASB 2019-3: Amendments to Australian accounting standards – interest rate benchmark This amendment amends specific hedge accounting requirements to provide relief from the potential effects of the uncertainty caused by interest rate benchmark reform. Initial adoption of AASB 2019-1: Amendments to Australian accounting standards – references to the conceptual framework This amendment amends Australian Accounting Standards, Interpretations and other pronouncements to reflect the issuance of Conceptual Framework for Financial Reporting by the AASB. The standards listed above did not have any impact on the amounts recognised in prior periods and are not expected to significantly affect the current or future periods. AASB 2020-4: Amendments to Australian Accounting Standards – COVID-19-Related Rent Concessions amends AASB 16 by providing a practical expedient that permits lessees to assess whether rent concessions that occur as a direct consequence of the COVID-19 (vii) Use of estimates and judgements The preparation of the consolidated financial statements requires management to make judgements, estimates and assumptions that affect the reported amounts in the financial statements. EMYRIA ANNUAL REPORT 2021 51 Management continually evaluates its judgements and estimates in relation to assets, liabilities, contingent liabilities, revenue and expenses. Management bases its judgements, estimates and assumptions on historical experience and on other various factors, including expectations of future events, management believes to be reasonable under the circumstances. The resulting accounting judgements and estimates will seldom equal the related actual results. The judgements, estimates and assumptions that have a significant risk of causing a material adjustment to the carrying amounts of assets and liabilities (refer to the respective notes) within the next financial year are discussed below. Share-based payment transactions The Group measures the cost of equity-settled transactions by reference to the fair value of the equity instruments at the date at which they are granted. The fair value is determined by using the Black- Scholes model taking into account the terms and conditions upon which the instruments were granted. The accounting estimates and assumptions relating to equity-settled share-based payments would have no impact on the carrying amounts of assets and liabilities within the next annual reporting period but may impact profit or loss and equity. Refer to note 12. Provision for impairment of receivables Included in trade and other receivables at the end of the reporting period is an amount of $12,523 (2020: $40,455) that is outstanding for more than 30 days. While there is inherent uncertainty, the directors understand that the full amount of debt is likely to be received and therefore no provision for impairment has been made. Impairment of non-financial assets Impairment exists when the carrying value of an asset or cash generating unit (“CGU”) exceeds its recoverable amount, which is the higher of its fair value less costs of disposal and its value in use. The fair value less costs of disposal calculation is based on available data from binding sales transactions, conducted at arm’s length, for similar assets or observable market prices less incremental costs for disposing of the asset. The value in use calculation is based on a Discount Cash Flow (“DCF”) model. The cash flows are derived from the budget for the next five years and do not include restructuring activities that the Group is not yet committed to or significant future investments that will enhance the asset’s performance of the CGU being tested. The recoverable amount is sensitive to the discount rate used for the DCF model as well as the expected future cash-inflows and the growth rate used for extrapolation purposes. Capitalisation of internally developed project development Distinguishing the research and development phases of a new project development and determining whether the recognition requirements for the capitalisation of development costs are met requires judgement. After capitalisation, management monitors whether the recognition requirements continue to be met and whether there are any indicators that capitalised costs may be impaired. Determining the lease term of contract with renewal and termination options – Group as lessee The Group determines the lease term as the non- cancellable term of the lease, together with any periods covered by an option to extend the lease if it is reasonably certain to be exercised, or any periods covered by an option to terminate the lease, if it is reasonably certain not to be exercised. The Group has a lease contract that includes an extension option. The Group applies judgement in evaluating whether it is reasonably certain whether or not to exercise the option to renew the lease. That is, it considers all relevant factors that create an economic incentive for it to exercise the renewal. After the commencement date, the Group reassesses the lease term if there is a significant event or change in circumstances that is within its control and affects its ability to exercise or not to exercise the option to renew or to terminate (e.g., construction of significant leasehold improvements or significant customisation to the leased asset). Coronavirus (COVID-19) pandemic Judgement has been exercised in considering the impacts that the Coronavirus (COVID-19) pandemic has had, or may have, on the Group based on known information. This consideration extends to the nature of the products and services offered, customers, supply chain and staffing. Other than as addressed in specific notes, there does not currently appear to be either any significant impact upon the financial statements or any significant uncertainties with respect to events or conditions which may impact the Group unfavourably 52 Notes to the consolidated financial statements For the year ended 30 June 2021 as at the reporting date or subsequently as a result of the Coronavirus (COVID-19) pandemic. (viii) Principles of consolidation The consolidated financial statements incorporate the assets, liabilities and results of entities controlled by Emyria at the end of the reporting year. A controlled entity is any entity over which Emyria has the ability and right to govern the financial and operating policies so as to obtain benefits from the entity’s activities. Where controlled entities have entered or left the Group during the year, the financial performance of those entities is included only for the period of the year that they were controlled. A list of controlled entities is contained in note 22 to the financial statements. In preparing the consolidated financial statements, all intragroup balances and transactions between entities in the consolidated Group have been eliminated in full on consolidation. (ix) New accounting standards and interpretations not yet mandatory or early adopted Certain new accounting standards and interpretations have been published that are not mandatory for 30 June 2020 reporting periods and have not been early adopted by the Group. The Group’s assessment of the impact of these new standards and interpretations is set out below. These standards are not expected to have a material impact on the entity in the current or future reporting periods and on foreseeable future transactions. 1.2 Significant accounting policies (i) Foreign currency translation Functional and presentation currency Items included in the financial statements of each of the Group’s entities are measured using the currency of the primary economic environment in which the entity operates (“the functional currency”). The consolidated financial statements are presented in the Australian dollar ($), which is the Group’s functional and presentation currency. Transactions and balances Foreign currency transactions are translated into the functional currency using the exchange rates at the dates of the transactions. Foreign exchange gains and losses resulting from the settlement of such transactions and from the translation of monetary assets and liabilities denominated in foreign currencies at year end exchange rates are generally recognised in profit or loss. They are deferred in equity if they relate to qualifying cash flow hedges and qualifying net investment hedges or are attributable to part of the net investment in a foreign operation. Foreign exchange gains and losses that relate to borrowings are presented in the statement of profit or loss, within finance costs. All other foreign exchange gains and losses are presented in the consolidated statement of profit or loss on a net basis within other income or other expenses. Non-monetary items that are measured at fair value in a foreign currency are translated using the exchanges rates at the date when the fair value was determined. Translation differences on assets and liabilities carried at fair value are reported as part of the fair value gain or loss. For example, translation difference on non- monetary assets and liabilities such as equities held at fair value through profit or loss are recognised in profit or loss as part of the fair value gain or loss and translation differences on non-monetary assets such as equities classified as financial assets are recognised in other comprehensive income. Group companies The results and financial position of foreign operations (none of which has the currency of a hyperinflationary economy) that have a functional currency different from the presentation currency are translated into the presentation currency as follows: • • assets and liabilities for each statement of financial position presented are translated at the closing rate at the date of that statement of financial position, income and expenses for each statement of profit or loss and statement of comprehensive income are translated at average exchange rates (unless this is not a reasonable approximation of the cumulative effect of the rates prevailing on the transaction dates, in which case income and expenses are translated at the dates of the transactions), and • all resulting exchange differences are recognised in other comprehensive income. On consolidation, exchange differences arising from the translation of any net investment in foreign entities, and of borrowings and other financial instruments EMYRIA ANNUAL REPORT 2021 53 designated as hedges of such investments, are recognised in other comprehensive income. When a foreign operation is sold or any borrowings forming part of the net investment are repaid, the associated exchange differences are reclassified to profit or loss, as part of the gain or loss on sale. Goodwill and fair value adjustments arising on the acquisition of a foreign operation are treated as assets and liabilities of the foreign operation and translated at the closing rate. (ii) Revenue from contracts with customers AASB 15 establishes a five-step model to account for revenue arising from contracts with customers and requires that revenue to be recognised at an amount that reflects the consideration to which an entity expects to be entitled in exchange for transferring goods or services to a customer. The five-step process outlined in AASB 15 are as follows: • • • • • identify the contract(s) with a customer; identify the performance obligations in the contract(s); determine the transaction price; allocate the transaction price to the performance obligations in the contract(s); and recognise revenue when (or as) the performance obligations are satisfied. Revenue is recognised when or as a performance obligation in the contract with customer is satisfied, i.e. when the control of the goods or services underlying the particular performance obligation is transferred to the customer. A performance obligation is a promise to transfer a distinct goods or service (or a series of distinct goods or services that are substantially the same and that have the same pattern of transfer) to the customer that is explicitly stated in the contract and implied in the Group’s customary business practices. Revenue is measured at the amount of consideration to which the Group expects to be entitled in exchange for transferring the promised goods or services to the customers, excluding amounts collected on behalf of third parties such as sales taxes or services taxes. If the amount of consideration varies due to discounts, rebates, refunds, credits, incentives, penalties or other similar items, the Group estimates the amount of consideration to which it will be entitled based on the expected value or the most likely outcome. If the contract with customer contains more than one performance obligation, the amount of consideration is allocated to each performance obligation based on the relative stand-alone selling prices of the goods or services promised in the contract. Revenue is recognised to the extent that it is highly probable that a significant reversal in the amount of cumulative revenue recognised will not occur when the uncertainty associated with the variable consideration is subsequently resolved. The control of the promised goods or services may be transferred over time or at a point in time. The control over the goods or services is transferred over time and revenue is recognised over time if: • • • the customer simultaneously receives and consumes the benefits provided by the Group’s performance as the Group performs; the Group’s performance creates or enhances an asset that the customer controls as the asset is created or enhanced; or the Group’s performance does not create an asset with an alternative use and the Group has an enforceable right to payment for performance completed to date. Revenue for performance obligation that is not satisfied over time is recognised at the point in time at which the customer obtains control of the promised goods or services. (a) Sales of service (revenue from patients and research projects and data deals) Revenue from rendering of service is recognised upon the delivery of service to the customers. (b) Research and development tax incentive Refund amounts receivable under the Federal Government’s Research and Development Tax Incentives are recognised as other income in the period it is received. (c) Interest Income Interest income is accrued on a time basis, by reference to the principal outstanding and at the effective interest rate applicable, which is the rate that exactly discounts estimated future cash receipts through the expected life of the financial asset to that assets’ net carrying amount on initial recognition. 54 Notes to the consolidated financial statements For the year ended 30 June 2021 (d) Government grants Government grants are assistance by the government in the form of transfers of resources to the Group in return for past or future compliance with certain conditions relating to the operating activities of the entity. Government grants include government assistance where there are no conditions specifically relating to the operating activities of the Group other than the requirement to operate in certain regions or industry sections. Government grants relating to income are recognised as income over the periods necessary to match them with the related costs and grants relating to assets are regarded as a reduction in asset. Government grants that are receivable as compensation for expenses or losses already incurred or for the purpose of giving immediate financial support to the Group with no future related costs are recognised net of expenses. (iii) Cash and cash equivalents Cash and cash equivalents include cash on hand and deposits with banks and highly liquid investments with original maturities of three months or less. (iv) Trade and other payables Trade and other payables represent the liability outstanding at reporting date for goods and services received by the Group during the reporting year, which remain unpaid. The balance is recognised as a current liability with the amounts normally paid within 30 days of recognition of the liability. Income Tax (v) The income tax expense or revenue for the year is the tax payable on the current year’s taxable income based on the applicable income tax rate for each jurisdiction adjusted by changes in deferred tax assets and liabilities attributable to temporary differences and to unused tax losses. Deferred income tax is provided on all temporary differences at the balance sheet date between the tax bases of the assets and liabilities and their carrying amounts for financial reporting purposes. Deferred income tax liabilities are recognised for all taxable temporary differences except where the deferred income tax arises from the initial recognition of an asset or liability in a transaction that is not a business combination and, at the time of transaction, affects neither the accounting profit nor taxable profit or loss. Deferred income tax assets are recognised for all deductible temporary differences, carry forward of unused tax assets and unused tax losses, to the extent that it is probable that taxable profit will be available against which the deductible temporary differences, and the carry forward of unused tax assets and unused tax losses can be utilised except where the deferred income tax asset relating to the deductible temporary difference arises from the initial recognition of an asset or liability in a transaction that is not a business combination and, at the time of the transaction, affects neither the accounting profit nor taxable profit or loss. The carrying amount of deferred income tax assets is reviewed at each balance sheet date and reduced to the extent that it is no longer probable that sufficient taxable profit will be available to allow all or part of the deferred income tax asset to be utilised. Deferred income tax assets and liabilities are measured at the tax rates that are expected to apply to when the asset is realised or the liability is settled, based on tax rates of (and tax laws) that have been enacted or substantially enacted at the balance sheet date. Income taxes relating to items recognised directly in equity are recognised in equity and not in the consolidated statement of comprehensive income. Issued capital (vi) Ordinary shares are classified as equity. Incremental costs directly attributable to the issue of new shares or options are shown in equity as a deduction, net of tax, from the proceeds. Basic earnings/(loss) per share Basic earnings/(loss) per share is calculated by dividing: • The profit/(loss) attributable to owners of the Group, excluding any costs of servicing equity other than ordinary shares By the weighted average number of ordinary shares outstanding during the financial year, adjusted for bonus elements in ordinary shares issued during the year. (vii) Impairment of assets At each reporting date, the Group reviews the carrying values of its tangible assets to determine whether there is an indication that those assets have been impaired. If such an indication exists, the recoverable amount of the asset, being the higher of the asset’s fair value less costs to sell and value in use, is compared to the EMYRIA ANNUAL REPORT 2021 55 asset’s carrying value. Any excess of the asset’s carrying value over its recoverable amount is expensed to the statement of comprehensive income. (viii) Financial instruments Classification and measurement Under AASB 9, the Group initially measures a financial asset as its fair value plus, in the case of financial asset not at fair value through profit or loss, transaction costs. Financial assets are then subsequently measured at fair value through profit or loss (“FVTPL”), amortised cost, or fair value through other comprehensive income (“FVOCI”). Initial recognition and measurement Financial assets are classified at initial recognition and subsequently measured at amortised cost, fair value through other comprehensive income (OCI), and fair value through profit or loss. The classification of financial assets at initial recognition depends on the financial asset’s contractual cash flow characteristics and the Group’s business model for managing them. With the exception of trade receivables that do not contain a significant financing component or for which the Group has applied the practical expedient, the Group initially measures a financial asset at its fair value plus, in the case of a financial asset not at fair value through profit or loss, transaction costs. Trade receivables that do not contain a significant financing component or for which the Group has applied the practical expedient are measured at the transaction price determined under AASB 15. Subsequent measurement The Group’s financial assets at amortised cost includes trade and other receivables. Impairment of financial assets For trade receivables, the Group applies a simplified approach in calculating expected credit losses (“ECLs”). Therefore, the Group does not track changes in credit risk, but instead recognises a loss allowance based on lifetime ECLs at each reporting date. Financial liabilities Initial recognition and measurement Financial liabilities are classified, at initial recognition, as financial liabilities at fair value through profit or loss, loans and borrowings, payables or as derivatives designated as hedging instruments in an effective hedge, as appropriate. All financial liabilities are recognised initially at fair value and, in the case of loans and borrowings and payables, net of directly attributable transaction costs. The Group’s financial liabilities include trade and other payables, borrowings and lease liabilities. Subsequent measurement Loans and borrowings After initial recognition, interest-bearing loans and borrowings are subsequently measured at amortised cost using the effective interest rate method. Gains and losses are recognised in profit or loss when the liabilities are derecognised as well as through the effective interest rate amortisation process. Amortised cost is calculated by taking into account any discount or premium on acquisition and fees or costs that are an integral part of the effective interest rate. The effective interest rate amortisation is included as finance costs in the statement of profit or loss. This category generally applies to interest-bearing loans and borrowings. Derecognition A financial liability is derecognised when the obligation under the liability is discharged or cancelled or expires. When an existing financial liability is replaced by another from the same lender on substantially different terms, or the terms of an existing liability are substantially modified, such an exchange or modification is treated as the derecognition of the original liability and the recognition of a new liability. The difference in the respective carrying amounts is recognised in the statement of profit or loss. Compound instruments The component parts of compound instruments (convertible bonds) issued by the Group are classified separately as financial liabilities and equity in accordance with the substance of the contractual arrangements and the definitions of a financial liability and an equity instrument. Conversion options that will be settled by the exchange of a fixed amount of cash or another financial asset for a fixed number of the Group’s own equity instruments is an equity instrument. At the date of issue, the fair value of the liability component is estimated using the prevailing 56 Notes to the consolidated financial statements For the year ended 30 June 2021 market interest rate for similar non-convertible instruments. This amount is recognised as a liability on an amortised cost basis using the effective interest method until extinguished upon conversion or at the instrument’s maturity date. The conversion option classified as equity is determined by deducting the amount of the liability component from the fair value of the compound instrument as a whole. This is recognised and included in equity, net of income tax effects, and is not subsequently remeasured. In addition, the conversion option classified as equity will remain in equity until the conversion option is exercised, in which case, the balance recognised in equity will be transferred to share capital. Where the conversion option remains unexercised at the maturity date of the convertible note, the balance recognised in equity will be transferred to retained earnings. No gain or loss is recognised in profit or loss and other comprehensive income upon conversion or expiration of the conversion option. Transaction costs that relate to the issue of the convertible notes are allocated to the liability and equity components in proportion to the allocation of the gross proceeds. Transaction costs relating to the equity component are recognised directly in equity. Transaction costs relating to the liability component are included in the carrying amount of the liability component and are amortised over the lives of the convertible notes using the effective interest method. (ix) Property, plant and equipment (i) Recognition and measurement Items of property, plant and equipment are measured at cost less accumulated depreciation and accumulated impairment losses. Cost includes expenditure that is directly attributable to the acquisition of the asset. The cost of self- constructed assets includes the cost of materials and direct labour, any other costs directly attributable to bringing the assets to a working condition for their intended use, the costs of dismantling and removing the items and restoring the site on which they are located and capitalised borrowing costs. Gains and losses on disposal of an item of property, plant and equipment are determined by comparing the proceeds from disposal with the carrying amount of property, plant and equipment and are recognised net within other income in profit or loss. When revalued assets are sold, the amounts included in the revaluation reserve are transferred to retained earnings. (ii) Subsequent costs The cost of replacing a part of an item of property, plant and equipment is recognised in the carrying amount of the item if it is probable that the future economic benefits embodied within the part will flow to the Group, and its cost can be measured reliably. The carrying amount of the replaced part is derecognised. The costs of the day-to-day servicing of property, plant and equipment are recognised in profit or loss as incurred. (iii) Depreciation Depreciation is calculated over the depreciable amount, which is the cost of an asset, or other amount substituted for cost, less its residual value. Depreciation is recognised in the profit or loss on a straight-line basis over the estimated useful lives of each part of an item of property, plant and equipment, since this most closely reflects the expected pattern of consumption of the future economic benefits embodied in the asset. Right-of-use assets are generally depreciated over the shorter of the assets’ useful life and the lease term on a straight-line basis. The depreciation rates used for each class of asset are: • • • fixtures and fittings 22.5% - 40% leasehold improvements 20% computer equipment and software 22.5% - 40% • Right-of-use assets 20% Depreciation methods, useful lives and residual values are reviewed at each financial year-end and adjusted if appropriate. (x) (a) Intangible assets Software Costs associated with maintaining software programmes are recognised as an expense as incurred. Development costs that are directly attributable to the design and testing of identifiable and unique software products controlled by the Group is recognised if, and only if, all of the following have been demonstrated: where the following criteria are met: • it is technically feasible to complete the software so that it will be available for use, EMYRIA ANNUAL REPORT 2021 57 • management intends to complete the software (c) Intangible assets acquired separately and use or sell it, there is an ability to use or sell the software, it can be demonstrated how the software will generate probable future economic benefits, adequate technical, financial and other resources to complete the development and to use or sell the software are available, and the expenditure attributable to the software during its development can be reliably measured. • • • • The Group amortises software with a limited useful life using the straight-line method between 2-5 years. (b) Research and development costs Research costs are expenses as incurred. Development expenditures on an individual project are recognised as an intangible asset when the Group can demonstrate: the technical feasibility to complete the intangible asset so that the asset will be available for use or sale, its intention to complete and its ability and intention to use or sell the asset, how the asset will generate future economic benefits, the availability of resources to complete the development of the asset, and • • • • • Intangible assets acquired separately are recorded at cost less accumulated amortisation and impairment. Amortisation is charged on a straight-line basis over their estimated useful lives when available for use. The estimated useful life and amortisation method is reviewed at the end of each annual reporting period, with any changes in these accounting estimates being accounted for on a prospective basis. (xi) Provisions Provisions are recognised when the Group has a present obligation (legal or constructive) as a result of a past event, it is probable that an outflow of resources embodying economic benefits will be required to settle the obligation and a reliable estimate can be made of the amount of the obligation. When the Group expects some or all of a provision to be reimbursed the reimbursement is recognised as a separate asset but only when the reimbursement is virtually certain. The expense relating to any provision is presented in the Statement of Profit or Loss and Other Comprehensive Income net of any reimbursement. Provisions are measured at the present value of management’s best estimate of the expenditure required to settle the present obligation at the reporting date. The discount rate used to determine the present value reflects current market assessments of the time value of money and the risks specific to the liability. the ability to measure reliably expenditure during development. The increase in the provision resulting from the passage of time is recognised in finance costs. Directly attributable costs that are capitalised include employee costs and an appropriate portion of relevant overheads. Capitalised development costs are recorded as intangible assets and amortised from the point at which the asset is ready for use. Following initial recognition of the development expenditure as an asset, the asset is carried at cost less any accumulated amortisation and accumulated impairment losses. Amortisation of the asset begins when development is complete and the asset is available for use. It is amortised over the period of expected future benefit. Amortisation is recorded in cost of sales. During the period of development, the asset is tested annually for impairment. (xii) Employee benefits (a) Equity settled compensation The Group operates equity-settled share-based payment employee share and option schemes. The fair value of the equity to which employees become entitled is measured at grant date and recognised as an expense over the vesting period, with a corresponding increase to an equity account. The fair value of shares is ascertained as the market bid price. The fair value of options is ascertained using a Black–Scholes pricing model which incorporates all market vesting conditions. The number of shares and options expected to vest is reviewed and adjusted at each reporting date such that the amount recognised for services received as consideration for the equity 58 Notes to the consolidated financial statements For the year ended 30 June 2021 instruments granted shall be based on the number of equity instruments that eventually vest. (b) Short-term obligations Liabilities for wages and salaries, including non- monetary benefits and annual leave expected to be settled within 12 months after the end of the period in which the employees render the related service are recognised in respect of employees’ services up to the end of the reporting period and are measured at the amounts expected to be paid when the liabilities are settled. The liability for annual leave is recognised in the provision for employee benefits. All other short-term employee benefit obligations are presented as payables. (c) Other long-term employee benefit obligations The liability for long service leave and annual leave which is not expected to be settled within 12 months after the end of the period in which the employees render the related service is recognised in the provision for employee benefits and measured as the present value of expected future payments to be made in respect of services provided by employees up to the end of the reporting period using the projected unit credit method. Consideration is given to expected future wage and salary levels, experience of employee departures and periods of service. Expected future payments are discounted using market yields at the end of the reporting period on national government bonds with terms to maturity and currency that match, as closely as possible, the estimated future cash outflows. (d) Share-based payments Share-based compensation benefits are provided to directors, employees and consultants via the option terms and conditions set out by the Group. The fair value of options granted under the option terms and conditions set out by the Group is recognised as a share-based payments expense with a corresponding increase in equity. The total amount to be expensed is determined by reference to the fair value of the options granted, which includes any market performance conditions and the impact of any non-vesting conditions but excludes the impact of any service and non-market performance vesting conditions. Non-market vesting conditions are included in assumptions about the number of options that are expected to vest. The total expense is recognised over the vesting period, which is the period over which all of the specified vesting conditions are to be satisfied. At the end of each period, the entity revises its estimates of the number of options that are expected to vest based on the non-market vesting conditions. It recognises the impact of the revision to original estimates, if any, in profit or loss, with a corresponding adjustment to equity. When the options are exercised, the Group transfers the appropriate number of shares to the director, employee or consultant. The proceeds received net of any directly attributable transaction costs are credited directly to equity. (e) Termination benefits Termination benefits are payable when employment is terminated before the normal retirement date, or when an employee accepts voluntary redundancy in exchange for these benefits. The Group recognises termination benefits when it is demonstrably committed to either terminating the employment of current employees according to a detailed formal plan without possibility of withdrawal or to providing termination benefits as a result of an offer made to encourage voluntary redundancy. Benefits falling due more than 12 months after the end of the reporting period are discounted to present value. (xiii) Goods and Services Tax (GST) Revenues, expenses and assets are recognised net of the amount of associated GST, except where the amount of GST incurred is not recoverable from the Australian Taxation Office. In these circumstances the GST is recognised as part of the cost of acquisition of the asset or as part of an item of the expense. Receivables and payables in the statements of financial position are stated inclusive of the amount of GST receivable or payable. Cash flows are presented in the statement of cash flows on a gross basis, except for the GST component of investing and financing activities, which are disclosed as operating cash flows. The net amount of GST recoverable from, or payable to, the taxation authority is included with other receivables or payables in the statements of financial position. EMYRIA ANNUAL REPORT 2021 59 (xiv) ROU assets and lease liability At inception of a contract, the Company assesses if the contract contains or is a lease. If there is a lease present, a right-of-use asset and a corresponding lease liability is recognised by the Group where the Group is a lessee. However, all contracts that are classified as short-term leases (lease with remaining lease term of 12 months or less) and leases of low-value assets are recognised as an operating expense on a straight-line basis over the term of the lease. Initially, the lease liability is measured at the present value of the lease payments still to be paid at the commencement date. The lease payments are discounted at the interest rate implicit in the lease. If this rate cannot be readily determined, the Group uses the incremental borrowing rate. The Group recognises a right-of-use asset at the commencement date of the lease. The right-of-use asset is initially measured at cost. The cost of right of use assets includes the amount of lease liabilities recognised, adjusted for any lease payments made at or before the commencement date, plus initial direct costs incurred and an estimate of costs to dismantle, remove or restore the leased asset, less any lease incentives received. Right-of-use assets are measured at cost comprising the following: • The amount of the initial measurement of lease liability • Any lease payments made at or before the commencement date less any lease incentives received • Any initial direct costs, and • Restoration costs. Subsequent to initial measurement, right-of-use assets are depreciated over the lease term or useful life of the underlying asset whichever is the shortest 60 Notes to the consolidated financial statements For the year ended 30 June 2021 Note 2: Revenue and expenses (a) Revenue Revenue from patients Revenue from research projects and data deals Other revenue Interest and other income Research and Development grant received Total Other revenue (b) Other expenses Travel and conference expenses Administration costs IT consultancy fees Consultancy fees (c) Depreciation and amortisation expense - Depreciation expense on right-of-use assets (note 6) - Depreciation expense on plant and equipment (note 7) - Amortisation expense on intangible assets (note 8) Group 2021 $ 1,207,543 768,366 1,975,909 23,148 954,180 977,328 (36,869) (149,921) (68,080) (406,053) (660,923) (176,923) (100,938) (67,014) (344,875) Group 2020 $ 745,720 267,732 1,013,452 25,046 468,177 493,223 (294,541) (63,727) (107,528) (169,646) 635,442 (217,914) (163,438) (2,129) (383,481) EMYRIA ANNUAL REPORT 2021 61 Note 3: Income tax (a) Income tax Current tax Current income tax expense Deferred tax Relating to the origination and reversal of previously unrecognised temporary deferred tax differences Net deferred tax assets not brought to account (b) Reconciliation of tax expense to net loss before tax Loss before income tax Tax at the statutory rate of 26.0% (2020: 27.5%) Tax effect of: Non-deductible expenses Effect of tax losses and timing differences not recognised as deferred tax assets Research and development costs Other non-assessable income Income tax expense (c) Amounts recognised in equity Aggregate current and deferred tax arising in the reporting period and not recognised in statement of profit or loss and other comprehensive income but directly debited or credited to equity Current tax Net deferred tax Unrecognised deferred tax asset Prior year tax losses not recognised Current year tax losses Capital raising costs and transaction costs in equity Plant and equipment Right-of-use asset lease liability Other temporary differences Off-set deferred tax liabilities Net deferred tax assets unrecognised Group 2021 $ $ - Group 2020 $ $ - (357,465) 357,465 - (805,144) 805,144 - (4,906,234) (1,275,621) (5,238,040) (1,440,461) 114,279 760,944 648,485 (248,087) - - 132,005 132,005 1,904,878 170,947 217,015 93,338 237,425 48,869 (278,123) 2,394,349 24,323 1,130,967 413,920 (128,749) - - 253,216 253,216 846,518 849,336 172,087 65,940 100,007 47,660 (176,670) 1,904,878 62 Notes to the consolidated financial statements For the year ended 30 June 2021 Deferred tax assets have not been brought to account at 30 June 2021 because the directors do not believe it is appropriate to regard realisation of the future tax benefit as probable. These benefits will only be obtained if: (i) the Group derives future assessable income of a nature and of an amount sufficient to enable the benefit from the deduction for the loss to be realised; (ii) the Group complies with the conditions for the deductibility imposed by law including the continuity of ownership and/or business tests; and (iii) no changes in tax legislation adversely affect the Group in realising the benefit from the deduction for the loss. Note 4: Cash and cash equivalents Cash at bank Cash and cash equivalents Group 2021 $ 6,528,926 6,528,926 Group 2020 $ 3,686,333 3,686,333 Notes to the statement of cash flows: For the purposes of the statement of cash flows, cash and cash equivalents include cash on hand and at bank and term deposits that has original maturity of less than 3 months. Note 5: Trade and other receivables Current Trade Debtors (1) GST paid Other Group 2021 $ 139,575 133,269 560 273,404 Group 2020 $ 93,750 24,256 3,609 121,615 The Group measures its trade and other receivables at amortised cost. (1) The ageing of the Group’s Trade Debtors as at 30 June 2021 and 30 June 2020 are as follows: EMYRIA ANNUAL REPORT 2021 63 30 June 2021 Debtor type Patient fees Project advisory fees Data collaboration revenue Gross carrying amount Expected loss rate Less allowing provision Net carrying amount 30 June 2020 Debtor type Patient fees Project advisory fees Data collaboration revenue Gross carrying amount Expected loss rate Less allowing provision Net carrying amount <30 days past due $ 30-90 days past due $ 12,271 60,065 54,716 127,052 0% - 127,052 5,120 - 4,409 9,529 0% - 9,529 <30 days past due $ 30-90 days past due $ 9,861 11.041 32,393 53,295 0% - 53,295 2,428 18.333 17,090 37,851 0% - 37,851 90+ days past due $ 2,994 - - 2,994 0% - 2,994 90+ days past due $ 2,604 - - 2,604 0% - 2,604 Total $ 20,385 60,065 59,125 139,575 0% - 139,575 Total $ 14,893 29,374 49,483 93,750 0% - 93,750 The Group applies the simplified approach in providing for expected credit losses prescribed by AASB 9. The expected credit losses on trade receivables are estimated using a provision matrix by reference to past defaults experience and analysis of the debtors’ current financial position. There has been no change in the estimation process used during the current reporting period. 64 Notes to the consolidated financial statements For the year ended 30 June 2021 Note 6: Right-of-use assets The Group’s lease portfolio includes office and clinic leases. The average term of these leases, excluding options, is 1-4 years. (a) Carrying value Value of leases Accumulated depreciation Reconciliation Net carrying amount at beginning of the year Add: leases entered into during the financial year Depreciation expense during the financial year Net carrying amount as at end of the year Group 2021 $ 1,329,414 (448,825) 880,589 323,390 734,122 (176,923) 880,589 Group 2020 $ 735,372 (411,982) 323,390 541,304 - (217,914) 323,390 (b) Total financial year end cash outflows for leases Repayment of lease liabilities (185,671) (215,385) (c) Options to extend or terminate The Group uses hindsight in determining the lease term where the contract contains options to extend or terminate the lease. EMYRIA ANNUAL REPORT 2021 65 Group 2021 $ 661,249 (295,685) 365,564 92,792 (58,810) 33,982 754,041 (354,495) 399,546 449,775 8,053 - (92,264) 365,564 148,530 - (105,874) - (8,674) 33,982 598,305 8,053 - (105,874) (100,938) 399,546 Group 2020 $ 653,196 (203,421) 449,775 198,666 (50,136) 148,530 851,862 (253,557) 598,305 651,692 - (74,365) (127,552) 449,775 54,793 52,367 - 77,256 (35,886) 148,530 706,485 52,367 2,891 - (163,438) 598,305 Note 7: Plant and equipment Leasehold Improvements At cost Accumulated Depreciation Computer, office furniture and equipment At cost Accumulated depreciation Total At cost Accumulated depreciation Reconciliation Leasehold improvements Carrying amount at beginning of the year Additions Reclassification Depreciation Carrying amount at the end of the year Computer, office furniture and equipment Carrying amount at beginning of the year Additions Plant and equipment written off Reclassified from leasehold improvements Depreciation Carrying amount at the end of the year Total Carrying amount at beginning of the year Additions Reclassification from software Plant and equipment write off Depreciation Carrying amount at the end of the year 66 Notes to the consolidated financial statements For the year ended 30 June 2021 Note 8: Intangible assets At cost Accumulated amortisation 30 June 2021 Balance at 1 July 2020 Additions Additions from internal development Amortisation Balance at 30 June 2021 Software 147,310 40,429 - (67,014) 120,725 Group 2021 $ 802,773 (69,143) 733,630 Development costs Patents & trademarks Group 2020 $ 149,439 (2,129) 147,310 Total 147,310 40,429 - - 559,513 - 559,513 - - 53,392 612,905 - 53,392 (67,014) 733,630 During the year, the Group capitalised development costs relating to Openly and EMD-003 projects. The Board assesses each project at balance date: i. Openly: The Company received TGA approval for its clinical management support web-based application software in September 2020. Costs associated with further development of this device have been capitalised. ii. EMD-003: relates to the use of cannabidiol for the treatment of psychological distress. During the year, Emyria filed a preliminary patent for the use of cannabidiol for the treatment of psychological distress. 30 June 2020 Balance at 1 July 2019 Additions Write off Reclassification to plant and equipment Amortisation Balance at 30 June 2020 Software 43,468 149,439 (40,577) (2,891) (2,129) 147,310 Development costs Patents & trademarks - - - - - - - - - - - - Total 43,468 149,439 (40,577) (2,891) (2,129) 147,310 There is no amortisation cost allocated to operating cost. EMYRIA ANNUAL REPORT 2021 67 Note 9: Financial liabilties carried at amortised costs Current Trade payables Accrued expenses and other payables Total trade and other payables (1) Borrowing at amortised cost (2) Lease liabilities (3) Non-Current Lease liabilities (3) Group 2021 $ 245,520 433,003 678,523 - 197,630 876,153 752,069 752,069 Group 2020 $ 149,049 312,075 461,124 247,154 152,689 860,967 210,972 210,972 (1) Trade and other payables are measured at amortised cost. None of the outstanding balance are past due at reporting date. (2) During the year ended 30 June 2020, the Group had secured a credit facility from Radium Capital and drew down on this facility in accordance with Radium Capital processes. The facility was secured against the R&D refund. The interest rate was 15% per annum and was repaid 30 November 2020. (3) The carrying value and reconciliation of the Group’s lease liabilities are as follows: Carrying value Current liabilities Non-current liabilities Carrying value as at 30 June Reconciliation Opening balance Add: leases entered into during the financial year Less: Principal repayments Add: Unwinding of interest expense on lease liability Carrying value as at 30 June Premises 2021 $ 197,630 752,069 949,699 363,661 725,283 (185,671) 46,426 949,699 Premises 2020 $ 152,689 210,972 363,661 541,096 - (215,385) 37,950 363,661 At initial recognition, the lease liabilities were measured at the present value of minimum lease payment using the Group’s incremental borrowing rate of 6%. The incremental borrowing rate was based on the unsecured interest rate that will apply if finance was sought for an amount and time period equivalent to the lease requirements of the Group. 68 Notes to the consolidated financial statements For the year ended 30 June 2021 Note 10: Provisions Current Employee benefits (1) Non-Current Make good provision (2) Group 2021 $ 156,120 156,120 97,000 97,000 Group 2020 $ 142,088 142,088 68,000 68,000 (1) The current provision for employee benefits includes all unconditional entitlements where employees have completed the required period of service and also those where employees are entitled to pro-rata payments in certain circumstances. The entire amount is presented as current as the Group expects all employees to take the full amount of accrued leave or require payment within the next 12 months. (2) Relates to the estimated cost of making good the premises in relation to the leases entered into by the Group in prior years. Note 11: Contributed equity (a) Issued and paid up capital Fully paid ordinary shares 254,091,857 19,310,804 183,902,778 11,751,953 2021 Number 2021 $ 2020 Number 2020 $ (b) Movements in fully paid shares on issue Opening Balance Movement for the year Shares issued at $0.18 per share Shares issued at $0.20 per share Convertible Notes issued at $0.16 per share Shares issued at $0.08 per share 27,500,000 Shares issued at $0.085 per share Shares issued at $0.175 per share 14,117,650 28,571,429 Capital raising costs Closing Balance* 183,902,778 11,751,953 130,500,000 2,872,738 2,777,778 500,000 30,000,000 6,000,000 20,625,000 3,300,000 - - - - (920,785) 2,200,000 1,200,000 5,000,000 (841,149) 254,091,857 19,310,804 183,902,778 11,751,953 EMYRIA ANNUAL REPORT 2021 69 *Of the total shares on issue as at 30 June 2021, 100,097,478 shares were in escrow from 24 months from the date of quotation being 12 February 2020. Ordinary shares Ordinary shares entitle the holder to participate in dividends and the proceeds on the winding up of the Group in proportion to the number of and amounts paid on the shares held. On a show of hands every member present at a meeting in person or by proxy shall have one vote and upon a poll each share shall have one vote. Options For information relating to the Company’s options, refer to Note 12. Note 12: Share based payments The following share-based payments arrangements were in existence during the current reporting year: Options Options series Number Grant date Expiry date Exercise Price $ Fair value at grant date $ (1) Issued on 7 June 2019 1,500,000 13/06/2019 13/06/2023 (2) Issued on 7 June 2019 9,750,000 13/06/2019 13/06/2023 (3) Issued on 19 June 2019 1,000,000 19/06/2019 13/06/2023 (4) Issued on 10 July 2019 3,500,000 10/07/2019 13/06/2023 (5) Issued on 26 September 2019 600,000 26/09/2019 26/09/2023 (6) Issued on 7 June 2019 1,000,000 24/10/2019 13/06/2023 (7) Issued on 11 November 2019 1,000,000 11/11/2019 13/06/2023 (8) Issued on 13 November 2020 3,500,000 24/09/2020 13/11/2024 (9) Issued on 13 November 2020 8,500,000 13/11/2020 13/11/2024 (10) Issued on 22 December 2020 500,000 22/12/2020 22/12/2023 (11) Issued on 22 December 2020 6,000,000 22/12/2020 22/12/2022 (12) Issued on 20 February 2021 1,500,000 20/02/2021 20/2/2024 (13) Issued on 18 March 2021 775,000 18/03/2021 18/3/2024 (14) Issued on 28 April 2021 5,000,000 28/04/2021 28/4/2023 Total 44,125,000 0.450 0.450 0.450 0.450 0.450 0.450 0.450 0.114 0.114 0.114 0.200 0.268 0.256 0.350 0.0008 0.0008 0.0008 0.0185 0.0188 0.0008 0.0496 0.0374 0.0320 0.0317 0.0136 0.0820 0.0620 0.0463 (1) The 1,500,000 options in series 1 which vested immediately were issued to consultants under the option terms and conditions issued by the Company. (2) The 9,750,000 options in series 2 which one third vested immediately on date of issue, one third vested after one year of employment and one third vests after two years of employment, were issued under the option terms and conditions issued by the Company. (3) The 1,000,000 options in series 3 which vested immediately were issued to consultants under the option terms and conditions issued by the Company. 70 Notes to the consolidated financial statements For the year ended 30 June 2021 Note 12: Share based payments (continued) (4) The 3,500,000 options in series 4 where one third vested immediately on date of issue, one third vests after one year of service and one third vests after two years of service from date of issue, were issued to a Director under the option terms and conditions issued by the Company. (5) The 600,000 options in series 5 where one third vested immediately on date of issue, one third vests after 12 months from date of issue and one third vests after 18 months from date of issue, were issued to a third party under the terms outlined in a licence agreement with the Company. (6) The 1,000,000 options in series 6 where one third vested immediately on date of issue, one third vests after one year of service and one third vests after two years of service from date of issue, were issued to a consultant under the option terms and conditions issued by the Company. (7) The 1,000,000 options in series 7 where one third vested immediately on date of issue, one third vests after one year of service and one third vests after two years of service from date of issue, were issued to an employee under the option terms and conditions issued by the Company. (8) The 3,500,000 options in series 8 where one third vested immediately on date of issue, one third vests after one year of service and one third vests after two years of service from date of issue, were issued to employees under the option terms and conditions issued by the Company. (9) The 8,500,000 options in series 9 where one third vested immediately on date of issue, one third vests after one year of service and one third vests after two years of service from date of issue, were issued to Directors under the option terms and conditions issued by the Company. (10) The 500,000 options in series 10 where one third vested immediately on date of issue, one third vests after one year of service and one third vests after two years of service from date of issue, were issued to a consultant under the option terms and conditions issued by the Company. (11) The 6,000,000 options in series 11 vested immediately were issued as part consideration to the lead manager in relation to a placement (12) The 1,500,000 options in series 12 is for advisory services where one third vested immediately on date of issue and the remainder over two years from date of issue, were issued to the financial adviser under the option terms and conditions issued by the Company. (13) The 775,000 options in series 13 where one third vested immediately on date of issue, one third vests after one year of service and one third vests after two years of service from date of issue, were issued to an employee under the option terms and conditions issued by the Company. (14) The 5,000,000 options in series 14 vested immediately were as part consideration to the lead manager for the placement on 28 April 2021. The weighted average contractual life for options outstanding at the end of the year was 3.22 years. The share based payments expense was $429,558 for the year ended 30 June 2021 (30 June 2020: $79,328). The amount of share based payments recognised to capital raising costs was $313,125. EMYRIA ANNUAL REPORT 2021 71 Options were priced using a Black-Scholes option pricing model using the inputs below: Options series Series 1 Series 2 Series 3 Series 4 Series 5 Series 6 Series 7 Grant date share price Exercise price Expected volatility $0.023 $0.023 $0.023 $0.10 $0.10 $0.023 $0.18 $0.45 70% $0.45 70% $0.45 70% $0.45 70% $0.45 70% $0.45 70% $0.45 70% Option life 4 years 4 years 4 years 4 years 4 years 4 years 4 years Dividend yield Interest rate 0% 1.08% 0% 0% 0% 0% 0% 0% 1.08% 1.08% 0.97% 0.70% 1.08% 0.70% Options series Series 8 Series 9 Series 10 Series 11 Series 12 Series 13 Series 14 Grant date share price Exercise price Expected volatility 0.083 0.076 0.084 0.087 0.210 0.175 0.205 0.114 70% 0.114 70% 0.114 70% 0.200 70% 0.268 70% 0.256 70% 0.350 70% Option life 4 years 4 years 3 years 2 years 3 years 3 years 2 years Dividend yield Interest rate 0% 0.3% 0% 0.3% 0% 0.2% 0% 0.09% 0% 0.1% 0% 0.1% 0% 0.1% The following reconciles the outstanding share options granted in the year ended 30 June 2021: 2021 Number of options 2021 Weighted avg exercise price 2020 Number of options 2020 Weighted avg exercise price Balance at the beginning of the year 18,350,000 Granted during the year* 44,766,598 Exercised during the year Expired during the year - - Balance at the end of the year 63,116,598 Un-exercisable at the end of the year 19,216,667 Exercisable at end of the year 43,899,931 0.45 0.24 - - 0.30 0.22 0.34 12,250,000 6,100,000 - - 18,350,000 9,816,667 8,533,333 0.45 0.45 - - 0.45 0.45 0.45 * includes 4,705,883 and 14,285,715 attaching options issued during the year. No amounts are unpaid on any of the shares. No person entitled to exercise an option had or has any rights by virtue of the option to participate in any share issue of any other body corporate. 72 Notes to the consolidated financial statements For the year ended 30 June 2021 Note 13: Reserves Convertible notes reserve (1) Share based payments reserve (2) Group 2021 $ - 826,746 826,746 Group 2020 $ - 84,063 84,063 (1) The Convertible note reserve was reversed on conversion of the convertible notes to shares in the prior year (2) The share based payments reserve relates to share options granted by the Company to its employees, consultants and Directors under the option terms and conditions issued by the Company. Further information about share based payments are set out in note 12. Movement of share based payments reserve Opening balance Share based payments: expense (note 12) Share based payments: capital raising costs Group 2021 $ 84,063 429,558 313,125 826,746 Note 14: Reconciliation of the loss from ordinary activities after income tax to the net cash flows used in operating activities Group 2021 $ Group 2020 $ 4,735 79,328 - 84,063 Group 2020 $ Loss for the year Share based payments expense Depreciation and amortisation Plant and equipment write-off Intangible asset write-off Changes in assets and liabilities: (Increase) in trade and other receivables and prepayments Increase in trade and other payables Increase in provisions (4,906,234) (5,238,040) 429,558 344,875 105,874 - (201,956) 247,533 43,031 79,328 383,481 - 40,578 (61,732) 243,485 100,429 Net cash flows (used in) operating activities (3,937,319) (4,452,471) Non-cash financing and investing activities The Group did not engage in any non-cash investing activities during the year (2020: nil). Changes in liabilities arising from financing activities Refer to Note 9 (3) for details. EMYRIA ANNUAL REPORT 2021 73 Note 15: Loss per share (a) Reconciliation of loss used in calculating Loss Per Share Loss attributable to the ordinary equity holders used in calculating basic loss per share Group 2021 $ Group 2020 $ (4,906,234) (5,238,040) (b) Weighted average number of shares used as the Denominator Ordinary shares used as the denominator in calculating basic loss per share 2021 Number $ 2020 Number $ 218,562,846 172,504,781 (c) Loss per share Basic loss per share (cents per share) Diluted loss per share (cents per share) 2021 cents (2.24) (2.24) 2020 cents (3.04) (3.04) There is no dilution of shares due to options as the potential ordinary shares are not dilutive, therefore not included in the calculation of diluted loss per share. Note 16: Related party transaction Key Management Personnel Compensation The aggregated compensation paid to Directors and Key Management Personnel of the Group is as follows: Short term employee benefits Post-employment benefits Non-monetary benefits (annual leave) Share based payment Group 2021 $ 1,597,755 85,207 (20,985) 269,716 1,931,693 Group 2020 $ 1,884,048 96,824 71,885 71,017 2,123,774 There have been no other transactions for the year ended 30 June 2021 to related parties. 74 Notes to the consolidated financial statements For the year ended 30 June 2021 Note 17: Parent entity disclosures Financial position Assets Current assets Non-current assets Total assets Liabilities Current liabilities Non-current liabilities Total liabilities Net assets Equity Issued capital Reserves Accumulated losses Total equity Financial performance Loss for the year Other comprehensive income Total comprehensive income Group 2021 $ 6,663,264 1,059,412 7,722,676 731,915 192,452 924,367 Group 2020 $ 3,269,139 1,463,187 4,732,326 783,818 13,000 796,818 6,798,309 3,935,508 19,310,804 826,746 (13,339,241) 6,798,309 11,751,953 84,063 (7,900,508) 3,935,508 (5,438,733) (5,085,449) - - (5,438,733) (5,085,449) Note 18: Commitments and contingencies At reporting date, there are no commitments or contingent liabilities outstanding for the Group or the Company. Note 19: Segment information AASB 8 ‘Operating Segments’ requires a “management approach” under which segment information is presented on the same basis as that useful for internal reporting purposes by the chief operating decision maker (“CODM”). For management purposes, the Group is organised into one main operating segment, being the research and development where the Group is a health care technology and clinical research company focused on generating high quality real-world evidence (RWE) data. The chief operating decision makers of the Group are the Executive Directors and Officers. All the Group’s activities are interconnected and all significant operating decisions are based on analysis of the Group as one segment. The financial results of the segment are the equivalent of the financial statements as a whole. At 30 June 2021, all revenues and material assets are considered to be derived and held in one geographical area being Australia. EMYRIA ANNUAL REPORT 2021 75 Note 20: Financial risk management The Group’s financial instruments consist mainly of deposits with banks and accounts receivable and payable. The Group’s activities expose it to a variety of financial risks: market risk (ie. interest rate risk), credit risk and liquidity risk. The Group’s overall risk management program focuses on the unpredictability of financial markets and seeks to minimise potential adverse effects on the financial performance of the Group. The Group uses different methods to measure different types of risk to which it is exposed. The Group’s Risk Committee (“the Committee) performs the duties of risk management in identifying and evaluating sources of financial and other risks. The Committee provides written principles for overall risk management which balance the potential adverse effects of financial risks on Group’s financial performance and position with the “upside” potential made possible by exposure to these risks and by considering the costs and expected benefits of the various methods available to manage them. Interest Rate Risk Interest rate risk is the risk that the fair value or future cash flows of financial instruments will fluctuate because of changes in market interest rates. The Group’s exposure to the risk of changes in market interest rates relates primarily to the Group’s Australian Dollar current and non-current debt obligations with floating interest rates. The Group is also exposed to interest rate risk on its cash and short term deposits. 2021 Fixed interest rate maturing in 1 year or less $ Fixed interest rate maturing greater than 1 year $ Floating Interest rate $ Non- interest bearing $ Total $ Weighted average effective interest rate $ Financial assets Cash and cash equivalents 6,528,736 Trade and other receivables Restricted cash - - 6,528,736 Financial liabilities Trade and other payables Borrowings Lease liabilities Convertible Notes - - - - - - - - - - - - 190 6,528,926 273,404 273,404 144,647 17,217 161,864 144,647 290,811 6,964,194 - - 678,523 678,523 - - - - 949,699 - 197,630 752,069 - - 197,630 752,069 678,523 1,628,222 1.00 - 1.00 - - 6.00 - 76 Notes to the consolidated financial statements For the year ended 30 June 2021 Note 20: Financial risk management (continued) 2020 Fixed interest rate maturing in 1 year or less $ Fixed interest rate maturing greater than 1 year $ Floating Interest rate $ Non- interest bearing $ Total $ Weighted average effective interest rate $ Financial assets Cash and cash equivalents 1,686,069 2,000,000 Trade and other receivables Restricted cash - - - - - - 150,558 264 3,686,333 121,615 6,000 121,615 156,558 1,686,069 2,000,000 150,558 127,879 3,964,506 Financial liabilities Trade and other payables Borrowings Lease liabilities - - - - - 247,154 - - 152,689 210,972 461,124 - - 461,124 247,154 363,661 399,843 210,972 461,124 1,071,939 0.57 - 1.00 - 15.00 6.00 Sensitivity Analysis – Interest Rate Risk The Group has performed a sensitivity analysis relating to its exposure to interest rate risk at the reporting date. This sensitivity analysis demonstrates the effect on the current period results and equity which could result from a change in interest rates. Change in loss Increase by 1% Decrease by 1% Credit risk 30 June 2021 $ 65,287 (65,287) 30 June 2020 $ 34,792 (34,792) The Group has no significant concentrations of credit risks. Credit risk arises from cash and cash equivalents, deposits with banks and financial institutions, as well as credit exposures to customers. The maximum exposure to credit risk at the reporting date is the carrying amount of the financial assets as summarised above of this note. As at 30 June 2021, all cash and cash equivalents were held with National Australia Bank with an A (Standard and Poor’s) credit rating. In relation to trade receivables, management assesses the credit quality of the customer, taking into account its financial position, past experience and other factors. The credit risk on other receivables is limited as it is comprised of GST recoverable from the Australian Taxation Office. The credit risk on liquid funds is limited because the counter party is a bank with high credit rating. EMYRIA ANNUAL REPORT 2021 77 Liquidity risk Prudent liquidity risk management involves the maintenance of sufficient cash, committed credit facilities and access to capital markets. It is the policy of the Board to ensure that the Group is able to meet its financial obligations and maintain the flexibility to pursue attractive investment opportunities through keeping committed credit lines available where possible, ensuring the Group has sufficient working capital. The Group manages liquidity risk by continuously monitoring forecast and actual cash flow Contractual maturities of financial liabilities As at the reporting date the Group had total financial liabilities of $1,628,222 (2020: $1,071,939) which comprised of trade and other payables and borrowings with a maturity of less than 6 months and lease liabilities maturing within the next four years. Capital risk management The Group manages its capital to ensure that it will be able to continue as a going concern while maximising the potential return to shareholders. The capital structure of the Company consists of equity attributable to equity holders, comprising issued capital and reserves as disclosed in notes 11 and 13. Fair value of financial assets and liabilities The fair value of financial assets and liabilities at approximate carrying values. Note 21: Fair value measurement Fair value hierarchy The Group’s assets and liabilities measured or disclosed at fair value, using a three level hierarchy, based on the lowest level of input that is significant to the entire fair value measurement, being: • • Level 1: Quoted prices (unadjusted) in active markets for identical assets or liabilities that the entity can access at the measurement date. Level 2: Inputs other than quoted prices included within Level 1 that are observable for the asset or liability, either directly or indirectly. • Level 3: Unobservable inputs for the asset or liability. The Group does not have assets and liabilities measured or disclosed at fair value as at 30 June 2021 and 2020. Estimates of fair value take into account factors and market conditions evident at balance date. Uncertainty and changes in global market conditions in the future may impact fair values in the future. Transfers between level 1, 2 and 3 There were no movements between different fair value measurement levels during the financial year (2020: none). 78 Notes to the consolidated financial statements For the year ended 30 June 2021 Note 22: Subsidaries Name of entity Emyria Clinical Network Pty Ltd Emyria Clinical Research Pty Ltd(1) Emyria Data Management Pty Ltd(1) Emyria IP Holdings Pty Ltd(1) Openly Care Inc. Emyria UK Ltd*(1) Country of incorporation Class of Shares Australia Australia Australia Australia United States United Kingdom Ordinary Ordinary Ordinary Ordinary Ordinary Ordinary 2021 100% 100% 100% 100% 100% 100% 2020 100% 100% 100% 100% 100% - * This entity was incorporated on 17 September 2020 (1) These entities have been dormant during the financial year. Note 23: Events after reporting date There are no matters or circumstances that have arisen since the end of the financial year which have significantly affected or may significantly affect the operations of the Group, the results of those operations, or the state of affairs of the Group in future financial periods. Note 24: Remuneration of auditors Auditor fees incurred during the financial year are as follows: Audit services – Stantons Group 2021 $ 51,074 51,074 Group 2020 $ 36,679 36,679 EMYRIA ANNUAL REPORT 2021 79 Directors’ declaration In the Directors’ opinion: a) the financial statements and notes set out on pages 45 to 78, and are in accordance with the Corporations Act 2001, including: i. giving a true and fair view of the Group’s financial position as at 30 June 2021 and of its performance, as represented by the results of its operations, changes in equity and its cash flows, for the year ended on that date; and ii. complying with Australian Accounting Standards, Corporations Regulations 2001 and other mandatory professional reporting requirements; b) there are reasonable grounds to believe that the Group will be able to pay its debts as and when they become due and payable. c) the financial statements and notes thereto are in accordance with International Financial Reporting Standards issued by the International Accounting Standards Board. This declaration is made after receiving the declarations required to be made to the Directors in accordance with section 295A of the Corporations Act 2001 for the year ended 30 June 2021. This declaration is made in accordance with a resolution of the Directors. Dr Michael Winlo Managing Director Dated 31 August 2021 80 Audit declaration EMYRIA ANNUAL REPORT 2021 Audit opinion 81 82 Audit opinion EMYRIA ANNUAL REPORT 2021 83 84 Audit opinion EMYRIA ANNUAL REPORT 2021 85 86 Audit opinion EMYRIA ANNUAL REPORT 2021 87 We’ve developed a clear strategy for value creation, with a focus on three key areas 1. Psychedelic- assisted therapy We have exclusive access to a library of quique MDMA-analogues with commercialisation potential as treatments for a range of neurological disorders and psychedelic-assisted therapies 2. Resistered medicines We’ve developed a novel, ultra-pure cannabinoid dose form that meets all FDA requirements. Pivotal registration trials are in planning for multiple target indications addressing unmet needs 3. Real world evidence We’ve built a robust, propriety clinical-trial-grade evidence asset to assist with multiple FDA and TGA registration programs 88 E MYRIA AN NUAL REPORT 2021 Corporate governance statement 89 The Board of Directors of Emyria Limited. (“Company”) is responsible for the corporate governance of the Company. The Board guides and monitors the business and affairs of the Company on behalf of the shareholders by whom they are elected and to whom they are accountable. This statement sets out the main corporate governance practices in place throughout the financial year in accordance with 4th edition of the ASX Principles of Good Corporate Governance and Best Practice Recommendations. This Statement was approved by the Board of Directors and is current as at 28 September 2021. Principle 1: Lay solid foundations for management and oversight ASX Recommendation 1.1: A listed entity should have and disclose a board charter setting out: (a) the respective roles and responsibilities of its board and management; and (b) those matters expressly reserved to the board and those delegated to management The Board has adopted a formal charter that details the respective Board and management functions and responsibilities. A copy of this Board charter is available in the corporate governance section of the Company’s website at www.emyria.com. ASX Recommendation 1.2: A listed entity should: (a) undertake appropriate checks before appointing a director or senior executive or putting someone forward for election as a director; and (b) provide security holders with all material information in its possession relevant to a decision on whether or not to elect or re-elect a director. The Company considers the character, industry and relevant experience, education and skill set, as well as interests and associations of candidates for appointment to the Board or as a senior executive and conducts appropriate checks to verify the suitability of the candidate, prior to their appointment. Information in relation to Directors seeking reappointment is set out in the Directors’ report and is included in the Notice of Annual General Meeting. ASX Recommendation 1.3: A listed entity should have a written agreement with each Director and Senior Executive setting out the terms of their appointment. The Company has in place written agreements with each Director and senior executive. ASX Recommendation 1.4: The Company Secretary of a listed company should be accountable directly to the Board, through the Chair, on all matters to do with the proper functioning of the Board. The Board Charter provides for the Company Secretary to be accountable directly to the Board through the Chair. ASX Recommendation 1.5: A listed entity should: (a) have and disclose a diversity policy; (b) through its board or a committee of the board30 set measurable objectives for achieving gender diversity in the composition of its board, senior executives and workforce generally; and (c) disclose in relation to each reporting period: (1) the measurable objectives set for that period to achieve gender diversity; (2) the entity’s progress towards achieving those objectives; and (3) either: (A) the respective proportions of men and women on the board, in senior executive positions and across the whole workforce (including how the entity has defined “senior executive” for these purposes); or (B) if the entity is a “relevant employer” under the Workplace Gender Equality Act, the entity’s most recent “Gender Equality Indicators”, as defined in and published under that Act.3. The Company has adopted a Diversity Policy which is available in the corporate governance section of the Company’s website at www.emyria.com. The Board considers that, due to the size, nature and stage of development of the Company, setting measurable objectives for the Diversity Policy at this time is not practical. The Board will consider setting measurable objectives as the Company increases in size and complexity. 90 Corporate governance statement As at 30 June 2021 the Company did not have any female Board members and had 3 female senior manager (2020:1). Of the balance of the Company’s employees 75% are female (2020: 50%). 68% (2020: 33%) of the Company’s employees in total, including Directors, are female. ASX Recommendation 1.6: A listed entity should: (a) have and disclose a process for periodically evaluating the performance of the board, its committees and individual directors; and (b) disclose for each reporting period whether a performance evaluation has been undertaken in accordance with that process during or in respect of that period. The Board has adopted a self-evaluation process to measure its own performance and the performance during each financial year. The Chairperson is also responsible for conducting an annual review of overall board performance during a regular meeting of the board. A performance review was undertaken during the reporting period. ASX Recommendation 1.7: A listed entity should: (a) have and disclose a process for evaluating the performance of its senior executives at least once every reporting period; and (b) disclose for each reporting period whether a performance evaluation has been undertaken in accordance with that process during or in respect of that period. The performance of executive Directors including the Managing Director is considered as part of the Board review process. The performance of other executives was reviewed and monitored by the Managing Director on an ongoing basis throughout the year. The Board reviews the business performance of the Company and its subsidiaries, whether strategic objectives are being achieved and the development of management and personnel at each formal board meeting. A performance review was undertaken during the reporting period. Principle 2: Structure the board to add value ASX Recommendation 2.1: The Board of a listed entity should: (a) have a nomination committee which: (1) has at least three members, a majority of whom are independent directors; and (2) is chaired by an independent director, and disclose: (1) the charter of the committee; (2) the members of the committee; and (3) as at the end of each reporting period, the number of times the committee met throughout the period and the individual attendances of the members at those meetings; or (b) if it does not have a nomination committee, disclose that fact and the processes it employs to address board succession issues and to ensure that the board has the appropriate balance of skills, knowledge, experience, independence and diversity to enable it to discharge its duties and responsibilities effectively. Due to the size and nature of the existing Board and the magnitude of the Company’s operations, the Company does not currently have a Nomination Committee. The full Board considers Board composition and identifies and assesses candidates to fill any casual vacancy which may arise from time to time. The Board considers that at this stage no efficiencies or other benefits would be gained by establishing a separate Nomination Committee. ASX Recommendation 2.2: A listed entity should have and disclose a Board skills matrix setting out the mix of skills and diversity that the Board currently has or is looking to achieve in its membership. On a collective basis the Board’s skills matrix indicates the mix of skills, experience and expertise that are considered necessary at Board level for optimal performance of the Board. The matrix reflects the Board’s objective to have an appropriate mix of specific industry and professional experience including skills such as medical expertise, drug development, RWE capture, leadership, governance, strategy, finance, risk management, Government and international business operations. EMYRIA ANNUAL REPORT 2021 91 A profile of each Director setting out their skills, experience and period of office is set out in the Directors’ Report of the latest Annual Report. ASX Recommendation 2.3: A listed entity should disclose: (a) the names of the directors considered by the board to be independent directors; (b) if a director has an interest, position or relationship of the type described in Box 2.3 (Factors relevant to assessing the independence of a director) but the board is of the opinion that it does not compromise the independence of the director, the nature of the interest, position or relationship in question and an explanation of why the board is of that opinion; and (c) the length of service of each director. The Board currently consists of Executive Directors Dr Stewart Washer, Dr Michael Winlo and Dr Alistair Vickery and Non-Executive Directors Mr Matthew Callahan and Sir John Tooke. Mr Callahan is not considered an independent Director due to an associated entity being a substantial shareholder in the Company. Sir John Tooke is considered an independent Director. As the Company’s activities develop in size, nature and scope, the composition of the Board and the implementation of additional corporate governance policies and structures, including further independent Directors will be reviewed. Dr Stewart Washer and Mr Mathew Callahan were appointed directors on 19 March 2018. Dr Alistair Vickery was appointed on 18 March 2019. Dr Michael Winlo was appointed on 7 November 2019 and Sir John Tooke was appointed on 10 February 2020. ASX Recommendation 2.4: The majority of the Board of a listed entity should be independent Directors. Due to the size and scale of the Company’s current activities, the Board does not consist of a majority of independent directors. The Board considers the composition of the Board, is appropriate given the size and current operations of the Company. To further facilitate independent decision-making, the Board has agreed procedures for Directors to have access in appropriate circumstances to independent professional advice. As the Company grows, the Board will consider the appointment of additional independent directors ASX Recommendation 2.5: The Chair of a listed entity should be an independent Director and, in particular, should not be the same person as the CEO of the entity. The Board has formed the view that, given the size and nature of the business of the Company, and the knowledge and experience Dr Stewart Washer brings to the Company, that Dr Washer is the most appropriate person to hold the position of Chairman of the Company even though he is not independent by reason of being an Executive Director. The Chairman is not the same person as the CEO of the entity, with Mr Michael Winlo performing this role. ASX recommendation 2.6: A listed entity should have a program for inducting new directors and for periodically reviewing whether there is a need for existing directors to undertake professional development to maintain the skills and knowledge needed to perform their role as directors effectively. Upon appointment to the Board new Directors will be provided with Company policies and will be provided an opportunity to discuss the Company’s operations with senior management and the Board. The Company encourages its Directors to participate in professional development opportunities to maintain the skills and knowledge needed to perform their role as directors effectively. Principle 3: Act ethically and responsibly ASX Recommendation 3.1: A listed entity should articulate and disclose its values. The Board has approved a statement of values and charges the Directors with the responsibility of inculcating those values across the Company. A copy of the Company’s statement of values is available on the Company’s website at www.emyria. com. ASX Recommendation 3.2: A listed entity should: (a) have and disclose a code of conduct for its directors, senior executives and employees; and (b) ensure that the board or a committee of the board is informed of any material breaches of that code. The Company has established a Code of Conduct that sets out the principles covering appropriate conduct in a variety of contexts and outlines the minimum standards of behavior expected from its Directors and employees. The Code of Conduct sets out policies in 92 Corporate governance statement relation to various corporate and personal behavior including safety, discrimination, respecting the law, anti-corruption, interpersonal conduct and conflict of interest. The Code contains a procedure tor reporting material breaches of the code. A copy of the Company’s code of conduct is available in the corporate governance section of the Company’s website at www.emyria.com. ASX Recommendation 3.3: A listed entity should: (a) have and disclose a whistleblower policy; and (b) ensure that the board or a committee of the board is informed of any material incidents reported under that policy. The Board has adopted a Whistleblower Protection Policy to ensure concerns regarding unacceptable conduct including breaches of the Company’s code of conduct can be raised on a confidential basis, without fear of reprisal, dismissal or discriminatory treatment. The purpose of this policy is to promote responsible whistle blowing about issues where the interests of others, including the public, or of the organisation itself are at risk. The policy contains a procedure tor reporting material breaches of the policy. A copy of the Company’s Whistleblower Protection Policy is available on the Company’s website at www.emyria.com. ASX Recommendation 3.4: A listed entity should: (a) have and disclose an anti-bribery and corruption policy; and (b) ensure that the board or a committee of the board is informed of any material breaches of that policy. The Board has adopted an Anti-Bribery and Anti- Corruption Policy for the purpose of setting out the responsibilities in observing and upholding the Company’s position on bribery and corruption provide information and guidance to those working for the Company on how to recognise and deal with bribery and corruption issues. The policy contains a procedure tor reporting material breaches of the policy. Principle 4: Safeguard integrity in financial reporting ASX Recommendation 4.1: The Board of a listed entity should: (a) have an audit committee which: (1) has at least three members, all of whom are non-executive directors and a majority of whom are independent directors; and (2) is chaired by an independent director, who is not the chair of the board, and disclose: (1) the charter of the committee; (2) the relevant qualifications and experience of the members of the committee; and (3) in relation to each reporting period, the number of times the committee met throughout the period and the individual attendances of the members at those meetings; or (b) if it does not have an audit committee, disclose that fact and the processes it employs that independently verify and safeguard the integrity of its corporate reporting, including the processes for the appointment and removal of the external auditor and the rotation of the audit engagement partner. The Board considers that the Company is not currently of a size, nor are its affairs of such complexity requiring the formation of a separate Audit Committee. The full Board carries out the duties that would ordinarily be assigned to the Audit Committee. ASX Recommendation 4.2: The Board of a listed entity should, before it approves the entity’s financial statements for a financial period, receive from its CEO and CFO (or equivalent) a declaration that, in their opinion, the financial records of the entity have been properly maintained and that the financial statements comply with the appropriate accounting standards and give a true and fair view of the financial position and performance of the entity and that the opinion has been formed on the basis of a sound system of risk management and internal control which is operating effectively. A copy of the Company’s Anti-Bribery and Anti- Corruption Policy is available on the Company’s website at www.emyria.com. The Board has received the assurance required by ASX Recommendation 4.2 in respect of the financial statements for the half year ended 31 December 2020 EMYRIA ANNUAL REPORT 2021 93 and the full year ended 30 June 2021. The Board has formed the view that, given the size and nature of the business of the Company, such a process is not required in relation to the Company’s quarterly cash flow reports. ASX Recommendation 4.3: A listed entity should disclose its process to verify the integrity of any periodic corporate report it releases to the market that is not audited or reviewed by an external auditor. When preparing periodic corporate reports for release to the market including the quarterly activity and cash flow reports, these reports are prepared and reviewed by the Managing Director before being presented to the Board for review. Such reports are not be released to market without the review process by the Managing Director and the Board. Principle 5: Make timely and balanced disclosure ASX Recommendation 5.1: A listed entity should have and disclose a written policy for complying with its continuous disclosure obligations under ASX Listing Rule 3.1. The Company has established a Continuous Disclosure Policy which is designed to guide compliance with ASX Listing Rule disclosure requirements, and to ensure that all Directors, senior executives and employees of the Company understand their responsibilities under the policy. In accordance with the Company’s continuous disclosure policy, all information provided to ASX for release to the market is posted to its website at www. emyria.com after ASX confirms an announcement has been made. Information in relation to the Company’s continuous disclosure requirements is set out in the Company’s corporate governance policy available at www.emyria.com. ASX Recommendation 5.3: A listed entity that gives a new and substantive investor or analyst presentation should release a copy of the presentation materials on the ASX Market Announcements Platform ahead of the presentation. The Board has appointed the Company Secretary as the person responsible for communicating with ASX and overseeing and coordinating the timely disclosure of information to ASX. The Company Secretary releases any new and substantive presentation to the ASX Market Announcements Platform ahead of the presentation, a copy of which is available on the Company’s website at www.emyria.com when released. Principle 6: Respect the rights of shareholders ASX Recommendation 6.1: A listed entity should provide information about itself and its governance to investors via its website. The Company’s website at www.emyria.com contains information about the Company’s operations, Directors and management and the Company’s corporate governance practices, policies and charters. All ASX announcements made to the market, including annual, half year and quarterly reports are posted on the website as soon as they have been released by the ASX. The full text of all notices of meetings and explanatory material, the Company’s Annual Report and copies of all investor presentations are posted on the Company’s website. ASX Recommendation 6.2: A listed entity should have an investor relations program that facilitates effective two-way communication with investors. The Company has adopted a Shareholder Communication Policy, which encourages shareholder participation and engagement with the Company. This policy has nominated the Chair, Managing Director and Company Secretary for having the primary responsibility for communicating with shareholders. ASX Recommendation 5.2: A listed entity should ensure that its board receives copies of all material market announcements promptly after they have been made. The Board has appointed the Company Secretary as the person responsible for communicating with ASX and overseeing and coordinating the timely disclosure of information to ASX. When the confirmation of a release is received from the ASX the Company Secretary promptly forwards a copy to the Board. The Company actively promotes communication with shareholders through a variety of measures, including the use of the Company’s website and email. The Company’s reports and ASX announcements may be viewed and downloaded from its website, www.emyria. com, or the ASX website, www.asx.com.au under the ASX code “EMD”. Contact with the Company can be made via an email address provided on the website and investors can subscribe to the Company’s electronic mailing list. 94 Corporate governance statement ASX Recommendation 6.3: A listed entity should disclose how it facilitates and encourages participation at meetings of security holders. The Shareholder Communication Policy encourages shareholder participation at shareholders’ meetings. Shareholders are provided with all notices of meeting prior to meetings. The Company’s auditor is also made available for questions at the annual general meeting. Shareholders are also always given the opportunity to ask questions of the Directors and management, either during or after shareholders’ meetings. The full text of all notices of meetings and explanatory material are posted on the Company’s website at www.emyria.com. ASX Recommendation 6.4: A listed entity should ensure that all substantive resolutions at a meeting of security holders are decided by a poll rather than by a show of hands. The Company will conduct a poll at meetings of security holders to decide each resolution. ASX Recommendation 6.5: A listed entity should give security holders the option to receive communications from, and send communications to, the entity and its security register electronically. Contact with the Company can be made via an email address provided on the website and investors can subscribe to the Company’s electronic mailing list. The Company’s share register provides a facility whereby investors can provide email addresses to receive correspondence from the Company electronically and investors can contact the share register via telephone, facsimile or email. Principle 7: Recognise and manage risk ASX Recommendation 7.1: The Board of a listed entity should: (a) have a committee or committees to oversee risk, each of which: (1) has at least three members, all of whom are non-executive directors and a majority of whom are independent directors; and (2) is chaired by an independent director, who is not the chair of the board, and disclose: (1) the charter of the committee; (2) the relevant qualifications and experience of the members of the committee; and (3) in relation to each reporting period, the number of times the committee met throughout the period and the individual attendances of the members at those meetings; or (b) if it does not have a risk committee or committees that satisfy (a) above, disclose that fact and the processes it employs for overseeing the entity’s risk management framework. The Board’s collective experience will assist in the identification of the principal risks that may affect the Company’s business. Key operational risks and their management will be recurring items for deliberation at Board meetings. A Risk Committee has been established by the Board. Members of the Risk Committee are John Tooke (Chair) Matthew Callahan and Alistair Vickery. The qualifications and experience of the members of the Risk Committee, and the number of times the committee met during the financial year are disclosed in the Directors’ Report contained in the Annual Report. As a consequence of the size and composition of the Company’s Board the Risk Committee does not have a majority of independent Directors, however the Bord considers the composition of the Risk Committee to be appropriate for the current size and activities of the Company. ASX Recommendation 7.2: The Board or a committee of the Board, of a listed entity should: (a) review the entity’s risk management framework at least annually to satisfy itself that it continues to be sound and review the entity’s risk management framework at least annually to satisfy itself that it continues to be sound and that the entity is operating with due regard to the risk appetite set by the board; and (b) disclose, in relation to each reporting period, whether such a review has taken place. The Board conducted such a review during the reporting period. The Company is committed to the identification; monitoring and management of risks associated with its business activities and has established policies in relation to the implementation of practical and EMYRIA ANNUAL REPORT 2021 95 effective control systems. The Company has established a Risk Management Framework and Policy. A review of the Company’s Risk Management Framework and Policy was carried out by the Risk Committee and the Board during the reporting period to satisfy itself that it continues to be sound and applicable to the Company’s activities. Social: The Company recognises that a failure to manage stakeholder expectations may lead to disruption to the Company’s operations. The Company’s Corporate Code of Conduct outlines the Company’s commitment to integrity and fair dealing in its business affairs and to a duty of care to all employees, clients and stakeholders. ASX Recommendation 7.3: A listed entity should disclose: (a) if it has an internal audit function, how the Principle 8: Remunerate fairly and responsibily ASX Recommendation 8.1: The Board of a listed entity should: function is structured and what role it performs; or (a) have a remuneration committee which: (b) if it does not have an internal audit function, that fact and the processes it employs for evaluating and continually improving the effectiveness of its governance, risk management and internal control processes. The Company does not have an independent internal audit function. Due to the nature and size of the Company’s operations, and the Company’s ability to derive substantially all of the benefits of an independent internal audit function in the manner disclosed below, the expense of an independent internal auditor is not considered to be appropriate. The Board, in conjunction with the Risk Committee, oversees the Company’s risk management systems, practices and procedures to ensure effective risk identification and management and compliance with internal guidelines and external requirements and monitors the quality of the accounting function. ASX Recommendation 7.4: A listed entity should disclose whether it has any material exposure to environmental and social risks and if it does, how it manages or intends to manage those risks. The Company identifies and manages material exposure to environmental and social risks in a manner consistent with its Risk Management Framework and Policy. Environmental: The Company is subject to, and responsible for, ensuring compliance with various regulations, licenses, approvals and standards so that its activities do not cause unauthorised environmental harm. Through its ongoing management of environmental activities, the Company has been able to operate in an environmentally sustainable and responsible manner. (1) has at least three members, all of whom are non-executive directors and a majority of whom are independent directors; and (2) is chaired by an independent director, and disclose: (1) the charter of the committee; (2) the members of the committee; and (3) as at the end of each reporting period, the number of times the committee met throughout the period and the individual attendances of the members at those meetings; or (b) if it does not have a remuneration committee, disclose that fact and the processes it employs for setting the level and composition of remuneration for directors and senior executives and ensuring that such remuneration is appropriate and not excessive. The Board as a whole performs the function of a Remuneration Committee which includes setting the Company’s remuneration structure, determining eligibilities to incentive schemes, assessing performance and remuneration of senior management and determining the remuneration and incentives of the Board. The Board considers that the Company is not currently of a size, nor are its affairs of such complexity requiring the formation of a separate Remuneration Committee. The Board may obtain external advice from independent consultants in determining the Company’s remuneration practices, including remuneration levels, where considered appropriate. 96 Corporate governance statement ASX Recommendation 8.2: A listed entity should separately disclose its policies and practices regarding the remuneration of Non-Executive Directors and the remuneration of Executive Directors and other senior executives. The remuneration of any Executive Director will be decided by the Board, without the affected Executive Director participating in that decision-making process. A Non-Executive Director may be paid fees or other amounts in accordance with any consultancy agreement in which they have an interest or as the Directors determine from time to time where a Director performs special duties or otherwise performs services outside the scope of the ordinary duties of a Director or any consultancy agreement in place. In addition, subject to any necessary Shareholder approval Directors may receive non-cash performance incentives such as options or performance rights. Directors are also entitled to be paid reasonable travel and other expenses incurred by them in the course of the performance of their duties as Directors. The Board reviews and approves the Company’s remuneration policy in order to ensure that the Company is able to attract and retain executives and Directors who will create value for Shareholders, having regard to the amount considered to be commensurate for an entity of the Company’s size and level of activity as well as the relevant Directors’ time, commitment and responsibility. The Board is also responsible for reviewing any employee incentive and equity-based plans including the appropriateness of performance hurdles and total payments proposed. ASX Recommendation 8.3: A listed entity which has an equity-based remuneration scheme should: (a) have a policy on whether participants are permitted to enter into transactions (whether through the use of derivatives or otherwise) which limit the economic risk of participating in the scheme; and (b) disclose that policy or a summary of it. The Company’s Trading Policy prohibits the use of derivatives in relation to unvested equity instruments, including performance share rights, and vested company securities that are subject to disposal restrictions (such as a “Holding Lock”. Derivatives may be used in relation to vested positions which are not subject to disposal restrictions subject to compliance with the law and the other provisions of the Trading Policy. EMYRIA ANNUAL REPORT 2021 97 ASX additional information Twenty largest shareholders as at 20 September 2021 Position Holder Name Holding (units) % total units Dr Stewart James Washer & Dr Patrizia Derna Washer (The Washer Family A/C) Mr Craig Lawrence Darby (Craig Lawrence Darby A/C) Mal Washer Nominees Pty Ltd (Mal Washer Family No1 A/C) Mercator Shipwrights Pty Ltd (Mecator A/C) Mr Sufian Ahmad (Sixty Two Capital A/C) Miss Sihong Zeng Ms Chunyan Niu Lakewest Pty Ltd (Raymond Desmond Family A/C) Mr Stephen Peter Somerville Rimoyne Pty Ltd Woodlands Opportunity Fund Pty Ltd Mr Bilal Ahmad Mr Pak Lim Kong Kobala Investments Pty Ltd (Fernando Edward Family A/C) Mr Lim Pak Kong Mr Craig Lawrence Darby D Schecter Medicine Professional Corporation Adam James(Araucaria A/C) Cs Fourth Nominees Pty Limited (Hsbc Cust Nom Au Ltd 11 A/C) Canopy Growth Corporation Diab Investments Pty Ltd (Diab Family A/C) Mr Boyun Liu Dr Stewart James Washer & Dr Patrizia Derna Washer (The Washer Family S/Fund A/C) 1 2 2 2 3 4 5 6 7 8 9 10 11 12 13 14 15 15 16 17 18 19 20 Total 28,400,000 19,600,000 19,600,000 19,600,000 10,276,210 6,523,385 5,882,546 5,731,960 4,900,000 3,831,244 3,551,757 3,450,000 3,416,667 2,600,000 2,370,930 2,000,000 1,960,000 1,960,000 1,683,576 1,562,500 1,554,622 1,549,962 1,325,599 11.18% 7.71% 7.71% 7.71% 4.04% 2.57% 2.32% 2.26% 1.93% 1.51% 1.40% 1.36% 1.34% 1.02% 0.93% 0.79% 0.77% 0.77% 0.66% 0.61% 0.61% 0.61% 0.52% 153,330,958 60.34% 98 ASX additional information Distribution of shareholders at 20 September 2021 Holding Ranges Holders Total Units Above 0 up to and including 1,000 Above 1,000 up to and including 5,000 Above 5,000 up to and including 10,000 Above 10,000 up to and including 100,000 above 100,000 Totals 22 357 344 716 233 1,672 6,041 1,235,831 2,868,456 25,684,181 224,297,348 254,091,857 The number of shareholders holding less than a marketable parcel is 71. Substantial shareholders at 20 September 2021 Stewart James Washer & Patrizia Derna Washer Mercator Shipwrights Pty Ltd Mr Craig Lawrence Darby Mal Washer Nominees Pty Ltd % Issued Share Capital 0.00% 0.49% 1.13% 10.11% 88.27% 100.00% 49,325,599 19,600,000 22,709,790 19,600,000 Class of shares and voting rights At meetings of members or classes of members each member entitled to vote may vote in person or by proxy or attorney; and on a show of hands every person present who is a member has one vote, and on a poll every person present in person or by proxy or attorney has one vote for each ordinary share held. On-market buy-back There is no current on-market buy-back Restricted securities as at 20 September 2021 Shareholder Ordinary shares Unlisted options Ordinary Shares – 24 Months from requotation 100,097,478 - Unlisted Options exercisable at $0.45 on or before 13 June 2023 – 24 Months from requotation - 10,500,000 Total 100,097,478 10,500,000 Listing Rule 4.10.19 confirmation The Company has used the cash and assets readily convertible to cash that it had at the time of admission to ASX in a way consistent with the business objectives set out in the prospectus. EMYRIA ANNUAL REPORT 2021 99 Unlisted Options as at 20 September 2021 - Part 1 Number of Holders and Holding Ranges $0.450 $0.450 $0.114 $0.200 13 June 2023 26 Sept 2023 13 Nov 2024 22 Dec 2022 - 14 14 - 100% 100% - 1 1 0% 100% 100% - 10 10 0% 100% 100% 14 8 22 22% 78% 100% 600,000 5,500,000 Exercisable at Expiring on No of holders and % issued: 10,001 - 100,000 > 100,000 Totals Holders (> 20%) of class not issued under employee incentive scheme Australian Medical Research Pty Ltd Sixty Two Capital Pty Ltd Bruce Robinson Karen Lesley Smith Mr Mufian Ahmad Unlisted Options as at 20 September 2021 - Part 2 Number of Holders and Holding Ranges $0.114 $0.268 $0.256 $0.350 22 Dec 2023 22 Feb 2024 18 Mar 2024 28 Apr 2023 - 1 1 0% 100% 100% - 1 1 0% 100% 100% 4 2 6 42% 58% 100% 32 28 60 10% 90% 100% Exercisable at Expiring on No of holders and % issued: 10,001 - 100,000 > 100,000 Totals Holders (> 20%) of class not issued under employee incentive scheme Australian Medical Research Pty Ltd Sixty Two Capital Pty Ltd Bruce Robinson 500,000 Karen Lesley Smith 1,500,000 Mr Mufian Ahmad 7,171,429 100 Corporate directory Directors Stewart Washer (Executive Chairman) Michael Winlo (Managing Director) Alistair Vickery (Executive Medical Director) John Tooke (Non-Executive Director) Matthew Callahan (Non-Executive Director) Company Secretary Simon Robertson Principal and registered office D2 661 Newcastle Street, Leederville WA 6007 PO Box 1442, West Leederville WA 6901 Telephone: 1300 436 363 Website: www.emyria.com.au Email: info@emyria.com Share registry Automic Pty Ltd Level 2, 267 St Georges Terrace Perth, Western Australia 6000 Auditor Stantons Level 2, 1 Walker Avenue West Perth Western Australia 6005 Bankers National Australia Bank Level 14, 100 St Georges Terrace Perth Western Australia 6000 Domestic stock exchange Australian Securities Exchange (ASX) Code: EMD EMYRIA ANNUAL REPORT 2021 Join our journey of clinical discovery and transformative care. emyria.com

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