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Guardion Health Sciences, Inc.

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FY2016 Annual Report · Guardion Health Sciences, Inc.
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C.  20549

FORM 10-K

x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
For the fiscal year ended December 31, 2016
OR
☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

Delaware
(State or other jurisdiction
of incorporation or
organization)

For the transition period from ____ to ____

Commission file number: 000-55723

GUARDION HEALTH SCIENCES, INC.
(Exact name of Registrant as specified in its charter)

15150 Avenue of Science, Suite 200
San Diego, California 92128
Telephone: 858-605-9055

  (Address and telephone number of principal executive offices)  

15150 Avenue of Science, Suite 200
San Diego, California 92128
Telephone: 858-605-9055
Telecopier: (858) 630-5543
(Address and telephone number of principal executive offices)

47-4428421

(I.R.S. Employer
Identification No.)

SECURITIES REGISTERED PURSUANT TO SECTION 12(b) OF THE EXCHANGE ACT:
None

SECURITIES REGISTERED PURSUANT TO SECTION 12(g) OF THE EXCHANGE ACT:
Common Stock, $0.001 par value

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. ☐ Yes ☒ No

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Exchange Act. ☐ Yes ☒ No

Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or Section 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days. ☒ Yes ☐ No

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to
be submitted and posted pursuant to Rule 405 of Regulation S-T (§ 232.405 of this chapter) during the preceding 12 months (or for such shorter period that
the registrant was required to submit and post such files). ☒ Yes ☐ No

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K (§ 229.405 of this chapter) is not contained herein, and will
not be contained, to the best of registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or
any amendment to this Form 10-K during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such
files). ☒

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the
definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer
Non-accelerated filer
(Do not check if a smaller reporting company)

☐
☐

Accelerated filer
Smaller reporting company

☐
x

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act). ☐ Yes ☒ No

Registrants’ common stock is not yet publicly traded.

As of March 17, 2017, there were outstanding 25,146,438 shares of the issuer’s common stock, $0.001 par value.

DOCUMENTS INCORPORATED BY REFERENCE: None.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TABLE OF CONTENTS

Page No.

PART 1

ITEM 1.
ITEM 1A.
ITEM 1B.
ITEM 2.
ITEM 3.
ITEM 4.

PART II

ITEM 5.

ITEM 6.
ITEM 7.

ITEM 7A.
ITEM 8.
ITEM 9.

ITEM 9A.
ITEM 9B.

PART III

ITEM 10.
ITEM 11.
ITEM 12.

ITEM 13.
ITEM 14.

PART IV

BUSINESS
RISK FACTORS
UNRESOLVED STAFF COMMENTS
PROPERTIES
LEGAL PROCEEDINGS
MINE SAFETY DISCLOSURES

MARKET FOR REGISTRANT’S COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND ISSUER
PURCHASES OF EQUITY SECURITIES
SELECTED FINANCIAL DATA
MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS
QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK
FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA
CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL
DISCLOSURE
CONTROLS AND PROCEDURES
OTHER INFORMATION

DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE
EXECUTIVE COMPENSATION
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED
STOCKHOLDER MATTERS
CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS AND DIRECTOR INDEPENDENCE
PRINCIPAL ACCOUNTANT FEES AND SERVICES

ITEM 15.

EXHIBITS AND FINANCIAL STATEMENT SCHEDULES

FINANCIAL STATEMENTS AND FOOTNOTES

SIGNATURES

ITEM 16.

FORM 10-K SUMMARY

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F-1

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Introductory Comment

Throughout  this  Annual  Report  on  Form  10-K,  the  terms  “we,”  “us,”  “our,”  “our  company,”  “Guardion”  the  “Company”  and  the  “Registrant”  refer  to
Guardion Health Sciences, Inc.

FORWARD LOOKING STATEMENTS

This  Annual  Report  on  Form  10-K  (the  “Report”)  contains  forward-looking  statements.    These  statements  relate  to  future  events  or  future  predictions,
including events or predictions relating to our future financial performance, and are based on current expectations, estimates, forecasts and projections about
us,  our  future  performance,  our  beliefs  and  management’s  assumptions.    They  are  generally  identifiable  by  use  of  the  words  “may,”  “will,”  “should,”
“expect,”  “plan,”  “anticipate,”  “believe,”  “feel,”  “confident,”  “estimate,”  “intend,”  “predict,”  “forecast,”  “potential”  or  “continue”  or  the  negative  of  such
terms  or  other  variations  on  these  words  or  comparable  terminology.    These  statements  are  only  predictions  and  involve  known  and  unknown  risks,
uncertainties  and  other  factors,  including  the  risks  described  under  “Risk  Factors”  that  may  cause  the  Company’s  or  its  industry’s  actual  results,  levels  of
activity, performance or achievements to be materially different from any future results, levels of activity, performance or achievements expressed or implied
by such forward-looking statements.  In addition to the risks described in Risk Factors, important factors to consider and evaluate in such forward-looking
statements  include:  (i)  general  economic  conditions  and  changes  in  the  external  competitive  market  factors  which  might  impact  the  Company’s  results  of
operations; (ii) unanticipated working capital or other cash requirements including those created by the failure of the Company to adequately anticipate the
costs associated with acquisitions and other critical activities; (iii) changes in the Company’s corporate strategy or an inability to execute its strategy due to
unanticipated changes; and (iv) the failure of the Company to complete any or all of the transactions described herein on the terms currently contemplated.
 As a result of these risks and uncertainties, many of which are described in greater detail elsewhere in the Risk Factors discussion, there can be no assurance
that the forward-looking statements contained in this Annual Report will in fact transpire.

Although  the  Company  believes  that  the  expectations  reflected  in  the  forward-looking  statements  are  reasonable,  the  Company  cannot  guarantee  future
results,  levels  of  activity,  performance  or  achievements.    The  Company  will  update  or  revise  the  forward-looking  statements  to  the  extent  required  by
applicable law.

3

 
 
 
 
 
 
 
 
 
ITEM 1. BUSINESS

Overview

PART I

The Company is a specialty health sciences company formed to develop, formulate and distribute condition-specific medical foods with an initial medical
food product on the market under the brand name Lumega-Z® that replenishes and restores the macular protective pigment. A depleted macular protective
pigment  is  a  modifiable  risk  factor  for  retina-based  diseases  such  as  age-related  macular  degeneration  (“AMD”),  computer  vision  syndrome  (“CVS”)  and
diabetic retinopathy. This risk may be modified by taking Lumega-Z to maintain a healthy macular protective pigment. Additional research has also shown a
depleted  macular  protective  pigment  to  be  a  biomarker  for  neurodegenerative  diseases  such  as  Alzheimer’s  and  dementia.  The  Company  has  had  limited
commercial operations to date, and has primarily been engaged in research and development and marketing.

The Company invented a proprietary technology, embodied in the MapcatSF® that accurately measures the macular pigment optical density (“MPOD”). On
November  8,  2016,  the  United  States  Patent  and  Trademark  Office  (“USPTO”)  issued  patent  number  9,486,136  for  the  MapcatSF  invention.  Using  the
MapcatSF to measure the MPOD allows one to monitor the increase in the density of the macular protective pigment after taking Lumega-Z. The MapcatSF is
a  non-mydriatic,  non-invasive  device  that  accurately  measures  the  MPOD,  the  lens  optical  density  and  lens  equivalent  age,  thereby  creating  an  evidence-
based protocol that is shared with the patient. A non-mydriatic device is one that does not require dilation of the pupil for it to function.

For the past three years, the clinical prototypes of the MapcatSF have been tested on patients, allowing for frequent modifications of the device’s algorithms
and retesting for accuracy, as well as to provide the inclusion of additional features not previously in the initial prototype. The alpha prototype, which is the
pre-commercial production version, was unveiled for the first time in July 2013 in Cambridge, United Kingdom, to researchers and scientists from around the
world.  The  MapcatSF  is  manufactured  and  assembled  in  Irvine,  California,  and  will  be  distributed  from  our  national  headquarters  in  San  Diego.  The
marketing of the device will be implemented through continuing education presentations conducted by key opinion leaders in the industry. The MapcatSF
device is a Class I medical device under the U.S. Food and Drug Administration (“FDA”) classification scheme for medical devices, which the Company has
determined does not require pre-market approval.

Lumega-Z is a medical food product that has a patent-pending formula that replenishes and restores the macular protective pigment simultaneously delivering
critical and essential nutrients to the eye. Management believes, based on review of products on the market and knowledge of the industry, that Lumega-Z is
the  first  liquid  ocular  health  formula  to  be  classified  as  a  medical  food  (as  defined  in  Section  5(b)  of  the  “Orphan  Drug Act”)  based  on  the  Company’s
determination. However, the FDA has not monitored nor approved Lumega-Z as a medical food. Formulated by Dr. Sheldon Hendler in 2010, modifications
were made over a two-year period to improve the taste and method of delivery. The current formulation has been delivered to patients and used in clinics
since 2014.

Medical  foods  are  not  considered  to  be  either  dietary  or  nutritional  supplements.  The  Company  believes  that  there  is  an  increasing  level  of  acceptance  of
medical foods as a primary therapy by patients and healthcare providers to treat pain syndromes, sleep and cognitive disorders, obesity, hypertension, and
viral  infection.  In  clinical  practice,  medical  foods  are  being  prescribed  as  both  a  standalone  therapy  and  as  an  adjunct  therapy  to  low  doses  of  commonly
prescribed drugs. The Company believes that medical foods will continue to grow in importance over the coming years.

Lumega-Z is a regulated medical food and therefore must be administered under the supervision of a physician or professional healthcare provider. In order to
reach the large, expanding AMD patient population, the Company primarily markets Lumega-Z to patients through ophthalmologists and optometrists.

4

 
 
 
 
 
 
 
 
 
 
 
 
 
Over  1,500  patients  have  been  treated  with  Lumega-Z  since  the  Company  began  selling  the  formulation  in  October  2011.  The  patients  come  from  a
combination of the three initial testing sites, healthcare provider sites where the MapcatSF has been demonstrated, patients that have found Lumega-Z online
and through other patient referrals, healthcare provider sites administering Lumega-Z to their patients without use of the MapcatSF, and MapcatSF devices
recently  placed  in  additional  healthcare  facilities.  Patients  take  Lumega-Z  under  the  supervision  of  their  physician.  Lumega-Z  is  typically  ingested  in  the
patient’s home on a daily basis. Patients are typically between 50 and 80 years old. Patients are mixed ethnically and socioeconomically. Patients typically
have insurance, whether private insurance or Medicare. Physicians have determined that the patient is experiencing or is at a high risk of developing retinal
disease and decide based on their medical determination that the patient is a candidate for Lumega-Z.

As the MapcastSF is specifically designed to measure the MPOD, the Company and the physicians are able to observe changes in that density in patients who
are taking Lumega-Z. The Company encourages sites using the MapcatSF® to provide us anonymized data on the MPOD readings. Anecdotal reports from
physicians indicate improvements in their patients such as increased visual function, a noticeable halt in the progression of the patient’s AMD, improvement
in  glare  and  contrast  sensitivity,  and  stabilization  and  improvement  of  vision.  No  adverse  effects  of  taking  Lumega-Z  have  been  reported  by  any  of  the
physicians administering Lumega-Z to their patients.

The  number  of  patients  regularly  ordering  Lumega-Z  has  steadily  increased  as  new  healthcare  providers  have  begun  working  with  the  Company,  with  a
concurrent  rise  in  patients  set  on  an  auto-ship  program  for  delivery  every  four  weeks.  Automatic  shipment  has  an  added  benefit  in  that  it  aids  physicians
because it increases patient compliance in using Lumega-Z on a regular basis. The Company’s operations, to date, indicate that each MapcatSF deployed in a
clinic generates an average of 75 new customers for our Lumega-Z product over a period of approximately 90 days when a MapcatSF is deployed in a small,
low volume clinic. A larger, higher volume clinic is expected to generate a larger number of patients in a shorter period of time. All of the Company’s revenue
is derived from a limited number of individual customers.

AMD is the leading cause of blindness in the world. More than 10 million people in the United States suffer from various forms of this incurable disease,
according to the American Macular Degeneration Foundation. As the population ages, that number is expected to triple by 2025. Congress, the Food and
Drug Administration, the Center for Medicare & Medicaid Services and private insurance companies are focusing increased efforts on pharmacovigilance (the
branch  of  the  pharmaceutical  industry  which  assesses  and  monitors  the  safety  of  drugs  either  in  the  development  pipeline  or  which  have  already  been
approved for marketing) to measure and reduce these adverse health consequences.

The Company believes that there is an increasing level of acceptance of medical foods as a primary therapy by patients and healthcare providers to treat pain
syndromes,  sleep  and  cognitive  disorders,  obesity,  hypertension,  and  viral  infection.  In  clinical  practice,  medical  foods  are  being  prescribed  as  both  a
standalone  therapy  and  as  an  adjunct  therapy  to  low  doses  of  commonly  prescribed  drugs.  From  a  regulatory  standpoint,  the  FDA  took  steps  in  1988  to
encourage the development of medical foods by regulating this product category under the Orphan Drug Act. The term “medical food” as defined in Section
5(b) of the Orphan Drug Act is a “food which is formulated to be consumed or administered internally (by mouth) under the supervision of a physician and
which is intended for the specific dietary management of a disease or condition for which distinctive nutritional requirements, based on recognized scientific
principles, are established by medical evaluation.” This definition was incorporated by reference into the Nutrition Labeling and Education Act of 1990.

These regulatory changes have reduced the costs and time associated with bringing medical foods to market. Until 1972, medical foods were categorized as
drugs and then until 1988 as “foods for special dietary purposes.” The field of candidates for development into medical foods is expanding due to continuing
advances in the understanding of the science of nutrition and disease, coupled with advances in food technology thereby increasing the number of products
that can be formulated and commercialized.

The Company distributes its products through E-commerce in an online store that is operated at www.guardionhealth.com.

5

 
 
 
 
 
 
 
 
 
 
 
Competitive Advantage

By combining the Company’s MapcatSF medical device and Lumega-Z medical food, Management believes the Company has developed the only reliable
two-pronged evidence-based protocol for replenishing and restoring the macular protective pigment and increasing overall retinal health. The MapcatSF is
intended  to  be  the  first  device  to  use  a  patented  “single  fixation”  process  and  “automatic  lens  density  correction”  that  produces  accurate  serialized  data.
Historically, a number of specialized densometers used by research groups within the medical community have been known to produce unreliable data; due in
part to the fact that they are not Troxler-free. The Troxler effect is an optical illusion affecting visual perception where an unchanging stimulus away from a
fixation point will fade away and disappear as one stares at a fixation point consistently. A device that is Troxler-free does not have this fading of images that
otherwise would occur as a result of the Troxler effect. Being Troxler-free is thought to be an important function in being able to accurately complete the
testing using these devices.

The MapcatSF has been installed in several teaching and ocular research facilities, such as the Illinois College of Optometry (“ICO”), the New York Eye and
Ear Infirmary, and the Rosenberg School of Optometry at the University of the Immaculate Word. While these collaborative relationships help further validate
the MapcatSF and Lumega-Z, these relationships are not material to the Company because none of these relationships is exclusive. There are many potential
collaborative partners available. The Company is free to enter into other collaborative relationships as needed. No sales of Lumega-Z are generated directly
from  Illinois  College  of  Optometry  because  the  MapcatSF  is  part  of  its  teaching  curriculum  and  not  used  for  direct  patient  care.  However,  the  other
collaborative relationships, as a result of using the MapcatSF on patients, periodically put patients on Lumega-Z if a physician determines it appropriate to do
so. The majority of sales of Lumega-Z primarily come from clinicians outside of these collaborative relationships.

Medical Foods Products Industry Overview

The science of nutrition was long overlooked and underdeveloped and has now shown that the sick and elderly have special nutritional needs that cannot be
met by traditional adult diets. Medical nutrition has emerged today as an attractive segment in the food industry.

A  number  of  diseases  are  associated  with  metabolic  imbalances,  and  patients  in  treatment  for  such  diseases  have  specific  nutritional  requirements.  Some
examples  are  ocular  health,  pain  syndromes,  insomnia,  cognitive  disorders,  IBS,  and  heart  disease.  Many  older  Americans  have  or  will  develop  chronic
diseases that are amenable to the dietary management benefits of medical foods. Medical foods help address these diseases and conditions in a drug-free way
with food-based ingredients, yet are still considered a medical product that should be taken under supervision by a physician. The term “medical foods” does
not pertain to all foods fed to sick patients. Medical foods are foods that are specially formulated and processed (as opposed to a naturally occurring foodstuff
used in a natural state) for patients who are seriously ill or who require the product as a major treatment modality according to FDA regulations.

Medical  foods  consist  of  food-based  ingredients  that  are  part  of  the  normal  human  diet  and  are  Generally  Recognized  as  Safe  (“GRAS”)  under  FDA
standards.  Medical  foods  must  make  disease  claims  for  which  there  is  scientific  evidence  that  nutrient  deficiencies  cannot  be  corrected  by  normal  diet.
Medical  foods  are  intended  for  a  vulnerable  population  suffering  from  a  particular  chronic  disease  and  therefor  have  special,  extra-rigorous  guarantees  of
safety. All ingredients must be designated GRAS and used in therapeutic concentrations to address the particular nutritional needs of the patient. Medical
foods are taken under the supervision of a physician or professional healthcare provider who monitors and adjusts the food ‘dosage.’ In addition, under FDA
guidelines and congressionally approved laws, medical foods do not require FDA preapproval but undergo continuous FDA monitoring and approval of label
claims. Even though pre-market FDA approval is not required for a medical food, the official requirements and responsibilities for the manufacturer, in terms
of safety, are greater than for dietary supplements, including solid scientific support for the formula as a whole. For these reasons, medical foods have greater
guarantees of efficacy. In contradistinction, dietary supplements, such as vitamins, minerals and botanicals, do not require FDA preapproval, cannot make
disease claims, are intended for normal people without disease and cannot claim that they prevent, mitigate or treat a given disease. Dietary supplements do
not require physician supervision and can be administered to a person that can self-administer the supplement without supervision.

Based on the advice of intellectual property counsel and regulatory affairs consultants, the Company believes Lumega-Z is properly categorized as a medical
food. While the Company believes it is unlikely the FDA would conclude otherwise, if the FDA were to determine Lumega-Z should not be defined as a
medical  food,  the  Company  would  need  to  relabel  and  rebrand  that  product.  The  Company  believes  there  would  be  minimal  impact  on  its  operations  and
financial  condition  if  it  were  required  to  change  labeling  and  packaging  back  to  that  of  a  dietary  supplement.  While  reclassification  and  the  subsequent
relabeling and rebranding would be an added cost to operations, it would not change the use or effectiveness of Lumega-Z, althought there is a chance that
certain physicians may choose not to recommend Lumega-Z to their patients or that certain consumers may choose not to buy Lumega-Z if it is not classified
as a medical food.

6

 
 
 
 
 
 
 
 
 
 
 
 
Competitive Strategy

Since  there  are  no  research-validated  pharmaceutical  solutions  for  slowing  the  progression  of  adult  macular  degeneration  (“AMD”),  it  is  necessary  for
physicians to recommend Age-Related Eye Disease Study (“AREDS”)-based supplements to AREDS-based AMD patients. However, more than 90% of all
AREDS-based  nutritional  products  currently  on  the  market  are  in  tablet,  capsule  and  gel  capsule  form.  As  previously  discussed,  tablets,  capsules  and  gel
capsules  have  a  low  efficiency  of  absorption.  For  this  reason,  some  doctors  may  hesitate  to  prescribe  tablet,  capsule  and  gel  capsule  form  AREDS-based
nutraceuticals despite the fact that these are currently the only options available to them.

The competitive landscape of supplements is crowded and confusing for physicians and patients looking to obtain an appropriate product for eye care. These
supplement products all have varying ingredients, varying levels of similar ingredients, varying claims regarding their effects, and varying price points.

Lumega-Z addresses this concern. In contrast, Lumega-Z is a liquid formulated using a proprietary molecular micronization process (“MMP”) to maximize
efficiency of absorption and safety and to minimize compatibility issues. The MMP is a proprietary homogenization process whereby the molecular structure
of the ingredients is reduced in size to facilitate more efficient absorption in the body.

Growth Strategy

Our Company believes that marketing its products is critical in ensuring its success. The Company has several marketing initiatives and will implement them
according to the success and product feedback that the Company and products create. The Company will also consider acquiring other companies and product
lines  that  may  be  complementary  or  supplementary  as  part  of  its  future  efforts  to  expand  the  business,  which  acquisitions  could  be  for  cash,  stock  or  a
combination thereof. The Company believes it can grow its business using the following sales and marketing strategies:

Sales and Marketing

Based  on  Management’s  knowledge  of  the  industry,  the  Company  believes  that  Lumega-Z  is  the  only  medical  food  in  the  ocular  health  space.  The  most
analogous products on the market are dietary supplements. While the medical food category is well established and growing for certain diseases or disorders
(for example, inborn errors of metabolism, metabolic syndrome, gastrointestinal disorders, neurological disorders), there are currently no medical foods other
than Lumega-Z specifically addressing ocular health. Thus, with regard to the ocular health market no such data is available regarding medical foods. The
most comparable industry is dietary supplements. In an attempt to effectively illustrate the market potential for Lumega-Z, the Company has examined ocular
health products in the dietary supplement market as the closest appropriate data set available. The use of dietary supplements to enhance health and well-
being  is  a  longstanding  and  increasing  trend.  According  to  industry  sources,  up  to  52%  of  adults  in  the  United  States  have  reported  taking  nutritional
supplements.  Worldwide  sales  of  supplements  surpassed  $53  billion  in  2007.  Supplementation  has  recently  generated  much  interest  among  health
professionals in a relatively new area, the prevention and slowing of the AMD epidemic.

U.S. Statistics

·
·
·

AMD is one of the leading causes of blindness in the developed world, responsible for 50% of blindness.
The United States has an estimated 15 million AMD cases.
One in three people in the U.S. will develop AMD or some vision-reducing eye disease by age 65.

7

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Worldwide Statistics

·
·

AMD is the third leading cause of blindness throughout the entire world, exceeded only by cataracts and glaucoma.
Overall,  the  prevalence  of  AMD  appears  to  be  lower  and  more  variable  in  the  developing  nations  as  compared  to  more  developed  countries.
Healthcare experts believe this will likely change for the worse with increasing life expectancy, changing lifestyles and increase in viewing computer
monitors.

Marketing Lumega-Z to Practitioners

In order to reach the large, expanding AMD patient population, the Company will primarily market Lumega-Z to the patients through ophthalmologists and
optometrists.  In  the  U.S.  alone,  there  are  more  than  18,515  ophthalmologists  and  over  34,000  optometrists  currently  practicing.  There  are  over  213,000
ophthalmologists worldwide. This marketing reach will be achieved through a combination of collaboration with industry-specific publishers, peer-to-peer
promotion using Key Opinion Leader clinicians, organic and paid search engine optimization and marketing, and other content-driven & educational tactics.

Sales Channel

Lumega-Z is a regulated Medical Food and therefore must be administered under the supervision of a physician or professional healthcare provider. Once the
healthcare provider has determined that the patient requires Lumega-Z, they will follow the following procedures:

·
·

·

The Company will provide all clinicians a DAC number (Doctor Authorization Code)
Patients will be given a customized recommendation from the clinician, including the DAC number; this will enable them to order Lumega-Z either
online or by calling the 800 number
Patients  will  be  able  to  take  advantage  of  using  their  Health  Care  Flexible  Spending  Accounts  (“HCFSA”)  or  Health  Savings  Account  (“HSA”)
dollars (pre-tax)

The Company will support the clinicians by making available Online Ocular Nutrition courses to train their technicians.

Proprietary Technology and Intellectual Property

Patents

The Company currently owns and has exclusive rights to the following patent and pending patent application:

Number

Patent
9,486,136
Patent
Application
14/028,104

Title

Owner

Product

File Date

APPARATUS FOR USE IN THE MEASUREMENT OF
MACULAR PIGMENT OPTICAL DENSITY AND/OR LENS
OPTICAL DENSITY OF AN EYE

EMULSION OF CAROTENOIDS AND OCULAR
ANTIOXIDANTS

GHS

GHS

MapcatSF®

08/11/14

Lumega-Z®

09/16/13

The MapcatSF® patent describes an apparatus for use in the measurement of the optical density of the macular protective pigment in the human eye, as well
as an apparatus for the use in measuring the lens optical density of a human eye. The apparatus is particularly applicable to flicker photometers, which are
used to measure the macular protective pigment in the human eye. On November 8, 2016, the United States Patent and Trademark Office (“USPTO”) issued
patent number 9,486,136 for the MapcatSF invention.

The Lumega-Z®  patent  filing  describes  a  daily  liquid  supplement  for  ocular  and  body  health  containing  at  least  one  of  the  following:  lutein,  zeaxanthin,
meso-zeaxanthin and astaxanthin for a human subject and for nutritionally supplementing macular pigments in the human eye. The micronized nutrients in a
lipid  based  emulsion  described  in  the  patent  application  are  more  efficiently  absorbed  into  the  bloodstream  than  conventional  supplement  formulations
resulting in higher serum levels and increased macular protective pigment.

8

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Trade Secrets

The MapcatSF® device employs a proprietary algorithm for correcting macular pigment optical density measurements with respect to lens density effects. 
More  particularly,  the  proprietary  algorithm  adjusts  the  photopic  luminosity  function  for  the  age  equivalence  of  the  subject’s  lens  using  a  relationship
disclosed by Sagawa and Takahashi (J. Opt. Soc. Am. 18, 2659-2667).  The algorithm is embedded in an integrated circuit block designed in such a way as to
make it difficult to reverse engineer.

Trademarks

The Company utilizes trademarks on all current products and believes that having distinguishing marks is an important factor in marketing its products. The
Company has three U.S. registered trademarks on the principal register at the USPTO. These marks are listed below. The Company has not sought any foreign
trademark protection for its products or product candidates at this time. U.S. trademark registrations are generally for fixed, but renewable, terms.

The Company currently owns and has exclusive rights to the following registered trademarks:

Registration No.
5,025,658
3,978,935
4,997,319

Mark
GUARDION
LUMEGA-Z
MAPCAT SF

Owner
GHS
GHS
GHS

Product
Guardion Health Sciences, Inc.
Lumega-Z
MapcatSF

Medical Foods and Medical Device Manufacturing and Sources and Availability of Raw Materials

The  Company  outsources  the  manufacturing  of  its  medical  food  products  and  medical  devices  to  contract  manufacturers.  The  Company  processes  orders
through  purchase  orders  and  invoices  with  each  manufacturer.  Healthy  Solutions,  LLC  in  Scottsdale,  Arizona  manufactures  Lumega-Z  for  the  Company.
Device Labs in Irvine, California manufactures the MapcatSF for the Company.

Government Regulation

Medical Food Statutory Definition and One FDA Regulation

Under  the  Federal  Food,  Drug,  and  Cosmetic  Act  of  1938  (“FDCA”),  products  are  regulated  on  the  basis  of  their  intended  use.  Their  intended  use  is
determined by the objective factors surrounding their use. Numerous categories and subcategories of products exist under the FDCA that could relate to our
products, such as food, food additive, dietary supplement, GRAS food component, new drug, GRAS and Effective (“GRAS/E”) drug for over the counter use,
and GRAS/E drug for use under the supervision of a physician. The categories overlap and products can fall within more than one category depending on
their intended use.

The FDA has provided little guidance on the regulation of medical foods, as it is still a relatively new and evolving category of product under the FDCA.

Our medical food products are defined and regulated by the FDA. The term medical food is a “food which is formulated to be consumed or administered
enterally, or by mouth, under the supervision of a physician and which is intended for the specific dietary management of a disease or condition for which
distinctive nutritional requirements, based on recognized scientific principles, are established by medical evaluation.” The FDA advises that it considers the
statutory definition of medical foods to “narrowly” constrain the types of products that fit within the category of food (see May 2007 Guidance, and Food
Labeling; Reference Daily Intakes and Daily Reference Values; Mandatory Status of Nutrition Labeling and Nutrition Content Revision proposed rule.) This
is a Final Rule and binding regulation on nutrition labeling for conventional foods.

9

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
The only FDA regulation pertaining to medical foods exempts them from the nutrition labeling requirements that apply to conventional foods, but they are
subject to special labeling requirements, as noted in the following excerpt:

(j) The following foods are exempt from this section or are subject to special labeling requirements:

(8) Medical foods as defined in section 5(b) of the Orphan Drug Act. A medical food is a food which is formulated to be consumed or administered enterally,
or by mouth, under the supervision of a physician and which is intended for the specific dietary management of a disease or condition for which distinctive
nutritional requirements, based on recognized scientific principles, are established by medical evaluation. A food is subject to this exemption only if: (i) It is a
specially formulated and processed product (as opposed to a naturally occurring foodstuff used in its natural state) for the partial or exclusive feeding of a
patient by means of oral intake or enteral feeding by tube; (ii) It is intended for the dietary management of a patient who, because of therapeutic or chronic
medical  needs,  has  limited  or  impaired  capacity  to  ingest,  digest,  absorb,  or  metabolize  ordinary  foodstuffs  or  certain  nutrients,  or  who  has  other  special
medically  determined  nutrient  requirements,  the  dietary  management  of  which  cannot  be  achieved  by  the  modification  of  the  normal  diet  alone;  (iii)  It
provides  nutritional  support  specifically  modified  for  the  management  of  the  unique  nutrient  needs  that  result  from  the  specific  disease  or  condition,  as
determined  by  medical  evaluation;  (iv)  It  is  intended  to  be  used  under  medical  supervision;  and  (v)  It  is  intended  only  for  a  patient  receiving  active  and
ongoing medical supervision wherein the patient requires medical care on a recurring basis for, among other things, instructions on the use of the medical
food.

Unlike regulation for drugs and for dietary supplements, there is no overall regulatory scheme for medical foods, or even a pending proposed rule, meaning
that  no  FDA  rulemaking  is  in  progress.  However,  a  very  detailed  Advanced  Notice  of  Proposed  Rulemaking  (“ANPR”)  entitled  “Regulation  of  Medical
Foods,” was published in the Federal Register on Nov. 29, 1996 (“ANPR 1996”). This ANPR never progressed to a proposed rule, or through the Notice and
Comment  procedure,  or  to  an  eventual  Final  Rule  (binding  regulation).  However,  the ANPR,  in  conjunction  with  the  May  2007  and  August  2013  Draft
Guidance  still  represents  the  FDA’s  position  and  policy  on  medical  foods.  This  ANPR  was  in  effect  withdrawn,  because  on  April  22,  2003,  the  FDA
published a proposal to withdraw numerous long-pending proposed rules, including this ANPR. The FDA cited as its reasons for withdrawal, first, that the
subjects  are  not  a  regulatory  priority,  and  agency  resources  are  limited;  second,  the  proposed  rules  have  become  outdated  due  to  advances  in  science  or
changes in the products or the industry regulated, or changes in legal or regulatory contexts; and, third, to eliminate uncertainty, so that the FDA or the private
sector may resolve underlying issues in ways other than those in the proposals. In May 2007, the FDA issued its Guidance to Industry relating to medical
foods (“2007 Guidance”), presumably because the medical foods sector was growing, but it did not engage in a formal rulemaking procedure, either because
it did not have the resources and/or because the medical foods category is still lower priority than drugs and medical devices. A third draft guidance was
issued  in  August  2013  further  attempting  to  clarify  the  FDA’s  position  on  medical  foods  (“August  2013  Draft  Guidance”).  The  guidance  has  not  been
formalized, however, the Company maintains compliance with this draft guidance.

Medical Food Regulatory Requirements

Overview:  Medical foods are FDA-regulated, but there is no complete set or scheme of regulations. There is no pre-market approval, or even pre-market
notification  required.  Rather,  it  is  the  responsibility  of  the  manufacturer  and  marketer  to  test  for  safety  and  efficacy  before  marketing  and  selling.  The
developer of a medical food must adhere closely to the statutory definition, and to the descriptions of a medical food in the sole FDA regulation regarding
exemption from nutrition labeling, and in the 2007 Guidance and the August 2013 Draft Guidance.

Threshold Issue: The manufacturer must demonstrate that the disease or condition to be targeted, scientifically and medically, is a disease with distinctive or
unique nutritional requirements. The FDA has stated that this is a “narrow category,” and that whether a product is valid for this category depends on the
published medical science of the disease and its origins. The targeted disease or condition may be, or caused by, a metabolic imbalance or deficiency or the
accelerated  requirements  for  a  certain  nutrient  caused  by  a  disease  state.  We  and  our  Scientific  Advisory  Board  examine  the  distinctive  nutritional
requirements of a disease.

10

 
 
 
 
 
 
 
 
 
 
 
Formulation: A  medical  food  may  not  be  a  single  ingredient  formula.  Otherwise,  that  product  would  be  a  dietary  supplement  for  a  nutrient  deficiency. A
medical food formula must go beyond a mere modification of the diet. The formula must meet and satisfy the distinctive nutritional requirements, not merely
ameliorate the symptoms. For example, Glucosamine or MSM, or an herb’s “active” constituent may indeed help osteoarthritis. One must demonstrate that
these nutrients are the distinctive nutritional requirements for osteoarthritis.

Safety: There is no particular or mandated FDA pre-market safety studies required of the formula as a whole. However, all ingredients must be either GRAS
or  approved  food-additives.  Since  medical  foods  are  typically  taken  with  prescription  drugs,  the  developer  must  assess  whether  any  medical  food/drug
interactions pose a risk. Many ingredients have been determined by the FDA to be GRAS and are listed as such by regulation. Other ingredients may achieve
self-affirmed  GRAS  status  through  a  panel  of  experts  on  that  particular  substance  that  author  a  GRAS  Report.  The  standard  for  an  ingredient  to  achieve
GRAS status requires not only technical demonstration of non-toxicity and safety, but also general recognition and agreement on that safety by experts in the
field.  All  ingredients  used  in  the  Company’s  medical  foods  are  either  FDA-approved  food  additives  or  have  GRAS  status.  The  GRAS  requirement  for
ingredients  is  arguably  a  higher  safety  standard  than  the  risk/benefit  analysis  required  for  pharmaceuticals.  Like  any  evolving  area,  especially  where  no
premarket approval is required, the FDA reserves the right to raise questions about the qualification of products within any category as well as the labeling
and manufacturing safety of those products.

Efficacy: No particular FDA pre-market efficacy studies are required by the FDA or by Congressional statute, similar to or comparable to Phase 2 & 3 trials
for  prescription  drugs.  However,  a  company  must  have  data  to  demonstrate  that  the  formula,  when  taken  as  directed,  meets  the  distinctive  nutritional
requirements of the particular disease.

Manufacturing: There are no GMP regulations for medical foods in particular. Drug GMPs are not required, nor are the relatively new dietary supplement
GMPs required; only food GMPs are required. The manufacture of the Company’s medical foods is outsourced in its entirety. The Company engages state of
the art facilities that manufacture only nutritional supplements and medical foods.

Labeling: As for all food labels, printing must be legible, and many required elements must be conspicuous, such as a statement of identity, which is the name
of  the  food;  the  statement:  “Must  be  administered  under  the  supervision  of  a  physician  or  professional  healthcare  provider;”  the  quantity;  the  ingredients
listing; the name and address of the distributor among other requirements.

Marketing: A  medical  food  is  a  food  product,  thus  the  FDA  does  not  regulate  advertisements  and  promotional  activities  according  to  the  pharmaceutical
statutes and regulations; there is no side effects disclaimer or fair balancing required, as in direct to consumer (“DTC”) advertising of drugs on television.
However,  the  FDA  has  a  very  broad  definition  of  “labeling”;  thus  all  promotional  materials,  including  websites,  are  under  the  authority,  monitoring  and
enforcement  of  FDA.  The  Federal  Trade  Commission  (“FTC”)  also  has  joint  jurisdiction  with  the  FDA  over  food  products,  per  a  1983  Memorandum  of
Understanding. Thus, all advertising claims, both express and implied, must be true, accurate, well-substantiated, and not misleading.

Enforcement: Enforcement is post-market, mostly via annual FDA inspections of food facilities, including packaging, distribution facilities, and fulfillment
houses, as well as the manufacturer. The FDA also gathers material at trade shows and conferences, and examines websites. The FTC has joint jurisdiction,
and performs sophisticated Internet searches, both randomly and at the request of the FDA or of a competitor.

Medical Device Regulatory Requirements

To fall within the purview of the FDA, a product must first meet the definition of a medical device, whereby it is then subject to regulation before and after it
is marketed. Section 201(h) of the FDCA defines a device as “an instrument, apparatus, implement, machine, contrivance, implant, in vitro reagent, or other
similar or related article, including any component, part, or accessory, which is ... intended for use in the diagnosis of disease or other conditions, or in the
cure, mitigation, treatment, or prevention of disease, in man or other animals.” If the product in question is not a medical device, then no regulation applies. If
it is a medical device, then one must evaluate applicable regulation.

11

 
 
 
 
 
 
 
 
 
 
 
 
 
Since 1976, the FDA’s paradigm has categorized medical devices in three distinct classes based on the potential health risks to the public – Class I, Class II,
and Class III. Medical devices are assigned a classification based on the level of control needed in order to provide the FDA reasonable assurance of the
product’s safety and effectiveness. If a device represents a very low risk of injury, it is considered Class I and does not require any premarket approval. While
most Class I devices are exempt from premarket notification requirements and regulations for good manufacturing practices, there are some general controls
that companies must conduct such as registering the company with the FDA, listing the device, paying an annual registration fee and tracking device activity.

Devices  that  present  an  intermediate  level  of  risk  of  injury  to  people  are  considered  Class  II.  The  FDA’s  perspective  is  that  for  Class  II  devices  “general
controls  alone  are  insufficient  to  assure  safety  and  effectiveness.”  In  addition  to  general  controls,  Class  II  devices  also  require  special  controls  such  as
specified content on labels, adherence to performance standards and surveillance of the product in the marketplace. Some medical devices are also subject to a
“Premarket  Notification”  under  Section  510(k)  of  the  FDCA.  Most  Class  I  and  some  Class  II  devices  are  exempt  from  the  510(k)  Premarket  Notification
requirement. If a Class II device is subject to the 510(k) requirement, the manufacturer must file a premarket notification with the FDA to demonstrate that
the  device  is  “substantially  similar”  to  another  Class  II  device  already  on  the  market.  Establishing  substantial  similarity  provides  the  FDA  reasonable
assurance that the device is safe and effective.

High risk devices are Class III. These are devices that either sustain human life or present an unreasonable risk of injury to humans. Because of the risks
involved, the FDA does not believe that general or special controls are sufficient to assure safety and effectiveness. The FDA requires general controls and
premarket approval (“PMA”) for Class III devices.

With  the  assistance  of  regulatory  affairs  consultants,  the  Company  has  determined  the  relevant  predicate  device  for  the  MapcatSF  is  the  MPS  II,  the
applicable product code for the MapcatSF is HJW and the applicable Code of Federal Regulation is 886.1050. The FDA has determined that this particular
predicate device, and related product code, is a Class I medical device. Based on this, the Company believes the MapcatSF is correctly classified as a Class I
medical device, is a safe medical device with a very low potential risk of injury to a patient and does not require any premarket approval.

Stark II

Congress enacted significant prohibitions against physician self-referrals in the Omnibus Budget Reconciliation Act of 1993. This law commonly referred to
as “Stark II,” applies to physician dispensing of outpatient prescription drugs that are reimbursable by Medicare or Medicaid. Our product, Lumega-Z, is not a
prescription drug, nor do we participate in Medicare, Medicaid or any other federal or state-funded program. Stark II, however, includes an exception for the
provision  of  in-office  ancillary  services,  including  a  physician’s  dispensing  of  outpatient  prescription  drugs,  provided  that  the  physician  meets  the
requirements of the exception. We are mindful that if our Lumega-Z product becomes eligible for reimbursement from any such program or if Lumega-Z
were deemed to be a prescription drug, Stark laws could potentially become applicable with regard to Lumega-Z.

Anti-Kickback Statute and HIPAA Criminal Laws

While we do not yet participate in any federal or state-funded healthcare programs, we are mindful that should we participate in such programs or should our
customers receive reimbursement or subsidy from a federal or state healthcare program, certain laws may become applicable to us. The federal Anti-Kickback
Statute makes it illegal for any person, including a pharmaceutical, biologic, or medical device company (or a party acting on its behalf), to knowingly and
willfully solicit, offer, receive or pay any remuneration, directly or indirectly, in exchange for, or to induce, the referral of business, including the purchase,
ordering  or  prescription  of  a  particular  item  or  service,  or  arranging  for  the  purchase,  ordering,  or  prescription  of  a  particular  item  or  service  for  which
payment may be made under federal healthcare programs such as Medicare and Medicaid. In 1996, under the Health Insurance Portability and Accountability
Act (“HIPAA”), the Anti-Kickback Statute was expanded to be made applicable to most federal and state-funded health care programs.

12

 
 
 
 
 
 
 
 
 
 
 
 
HIPAA Compliance and Privacy Protection

HIPAA  established  comprehensive  federal  protection  for  the  privacy  and  security  of  health  information.  The  HIPAA  standards  apply  to  three  types  of
organizations,  or  “Covered  Entities”:  (1)  health  plans,  (2)  health  care  clearing  houses,  and  (3)  health  care  providers  who  conduct  certain  health  care
transactions electronically. Covered Entities must have in place administrative, physical and technical standards to guard against the misuse of individually
identifiable health information. Additionally, some state laws impose privacy protections more stringent than HIPAA’s. There are also international privacy
laws, such as the European Data Directive, that impose restrictions on the access, use, and disclosure of health information. All of these laws may impact the
Company’s business in the future.

HITECH Act

The  Health  Information  Technology  for  Economic  and  Clinical  Health  (“HITECH”)  Act  promotes  the  adoption  and  meaningful  use  of  health  information
technology. The HITECH Act addresses the privacy and security concerns associated with the electronic transmission of health information, in part, through
several provisions that strengthen the civil and criminal enforcement of the HIPAA rules.

State Regulatory Requirements

Each  state  has  its  own  regulations  concerning  physician  dispensing,  restrictions  on  the  corporate  practice  of  medicine,  anti-kickback  and  false  claim
regulations. In addition, each state has a board of pharmacy that regulates the sale and distribution of drugs and other therapeutic agents. Some states require
that a physician obtain a license to dispense prescription products. When considering the commencement of business in a new state, the Company consults
with healthcare counsel regarding the expansion of operations and utilizes local counsel when necessary.

13

 
  
 
 
 
 
 
 
 
 
Other United States Regulatory Requirements

In  the  United  States,  the  research,  manufacturing,  distribution,  sale,  and  promotion  of  drug  and  biological  products  are  subject  to  regulation  by  various
federal, state, and local authorities in addition to the FDA, including the Centers for Medicare and Medicaid Services (formerly the Health Care Financing
Administration),  other  divisions  of  the  United  States  Department  of  Health  and  Human  Services  (e.g.,  the  Office  of  Inspector  General),  the  United  States
Department of Justice and individual United States Attorney offices within the Department of Justice, and state and local governments. Pricing and rebate
programs must comply with the Medicaid rebate requirements of the Omnibus Budget Reconciliation Act of 1990 and the Veterans Health Care Act of 1992,
each as amended. If products are made available to authorized users of the Federal Supply Schedule of the General Services Administration, additional laws
and  requirements  apply.  All  of  these  activities  are  also  potentially  subject  to  federal  and  state  consumer  protection,  unfair  competition,  and  other  laws.  In
addition, we may be subject to federal and state laws requiring the disclosure of financial arrangements with health care professionals.

Foreign Regulatory Requirements

While not yet applicable to us, we may eventually be subject to widely varying foreign regulations, which may be quite different from those of the FDA,
governing  clinical  trials,  manufacturing,  product  registration  and  approval,  and  sales.  Whether  or  not  FDA  approval  has  been  obtained,  we  must  obtain  a
separate  approval  for  a  product  by  the  comparable  regulatory  authorities  of  foreign  countries  prior  to  the  commencement  of  product  marketing  in  these
countries. In certain countries, regulatory authorities also establish pricing and reimbursement criteria. The approval process varies from country to country,
and the time may be longer or shorter than that required for FDA approval.

Corporate History

Guardion Health Sciences, Inc. was formed under the name P4L Health Sciences, LLC in December, 2009 in California as a limited liability company. The
Company changed its name to Guardion Health Sciences, LLC in December 2009. In June 2015, the Company converted into a Delaware “C” corporation.

Implications of Being an Emerging Growth Company

As a company with less than $1.0 billion in revenue during its most recently completed fiscal year, the Company qualifies as an “emerging growth company”
as defined in Section 2(a) of the Securities Act of 1933, as amended (the “Securities Act”), as modified by the Jumpstart Our Business Startups Act of 2012,
(“JOBS  ACT”).  As  an  emerging  growth  company,  the  Company  may  take  advantage  of  specified  reduced  disclosure  and  other  requirements  that  are
otherwise applicable, in general, to public companies that are not emerging growth companies. These provisions include:

·
·
·
·

Reduced disclosure about our executive compensation arrangements;
No requirement for a non-binding shareholder advisory votes on executive compensation or golden parachute arrangements;
Exemption from the auditor attestation requirement in the assessment of our internal control over financial reporting; and
Reduced disclosure of financial information in this Annual Report, limited to two years of audited financial information and two years of selected
financial information.

As a smaller reporting company, each of the foregoing exemptions is currently available. The Company may take advantage of these exemptions for up to
five years or such earlier time that we are no longer an emerging growth company. The Company would cease to be an emerging growth company if we have
more than $1.0 billion in annual revenues as of the end of a fiscal year, if we are deemed to be a large accelerated filer under the rules of the Securities and
Exchange Commission (“SEC”), or if we issue more than $1.0 billion of non-convertible debt over a three-year-period.

The JOBS Act permits an emerging growth company to take advantage of an extended transition period to comply with new or revised accounting standards
applicable to public companies. Therefore, we will not be subject to the same new or revised accounting standards as other public companies that are not
emerging growth companies.

Employees

As of March 17, 2017, the Company had a staff of eight, consisting of three officers, four full-time staff and one part-time staff person.

14

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ITEM 1A. RISK FACTORS

Investing in the Company’s common stock involves a high degree of risk. Prospective investors should carefully consider the risks described below, together
with all of the other information included or referred to in this Form 10-K, before purchasing shares of the Company’s common stock. There are numerous
and varied risks that may prevent the Company from achieving its goals. If any of these risks actually occurs, the business, financial condition or results of
operations may be materially adversely affected. In such case, the trading price of the Company’s common stock could decline and investors could lose all or
part of their investment.

Risks Related to the Company’s Business

The Company’s recurring operating losses have raised substantial doubt regarding its ability to continue as a going concern.

The Company has sustained recurring operating losses, which raises substantial doubt about its ability to continue as a going concern. The perception of the
Company’s ability to continue as a going concern may make it more difficult for it to obtain financing for the continuation of its operations and could result in
the loss of confidence by investors, suppliers and employees. The Company’s audited financial statements for the year ended December 31, 2016 have been
prepared assuming the Company will continue as a going concern. As discussed in Note 1 to the Financial Statements the continuation of the Company as a
going concern is dependent upon the Company raising additional debt and/or equity financing to fund future operations and to provide additional working
capital. As a result, management has concluded that there is substantial doubt about the Company’s ability to continue as a going concern within one year of
the date that the consolidated financial statements are issued.

The Company’s auditors have also included explanatory language in their opinion that there is substantial doubt about the Company’s ability to continue as a
going concern. If the Company is unable to raise additional capital, the Company will be forced to suspend or terminate operations and, in all likelihood,
cause investors to lose their entire investment.

The  Company  has  significant  working  capital  requirements  and  has  historically  experienced  negative  working  capital  balances.  If  the  Company
continues to experience such negative working capital balances in the future, it could have a material adverse effect on its business, financial condition
and results of operations.

As a result of its continued losses, the Company’s current liabilities significantly exceed current assets, resulting in negative working capital of $470,064 at
December 31, 2016.  The Company is dependent upon obtaining additional financing to meet working capital needs and repay outstanding debt. Since its
formation, the Company has relied on convertible notes and direct stock purchases from unrelated parties to fund its operating cash flow deficits. There is no
assurance that it will generate the necessary net income or operating cash flows to meet its working capital requirements and pay its debts as they becomes
due in the future due to a variety of factors and other factors discussed in this “Risk Factors” section. There can be no assurance, however, that it will be able
to successfully take any of these actions, including adjusting expenses sufficiently or in a timely manner, or raising additional equity, increasing borrowings or
completing  a  refinancing  on  any  terms  or  on  terms  that  are  acceptable  to  it.  The  Company’s  inability  to  take  these  actions  as  and  when  necessary  would
materially adversely affect its liquidity, results of operations, financial condition and ability to operate.

The Company’s future success is largely dependent on the successful commercialization of Lumega-Z® and the MapcatSF®.

The future success of the Company’s business is largely dependent upon the successful commercialization of its medical food, Lumega-Z, and its medical
device, the MapcatSF. The Company is dedicating a substantial amount of its resources to advance Lumega-Z and certain resources to advance MapcatSF as
aggressively  as  possible.  If  the  Company  encounters  difficulties  in  the  commercialization  of  Lumega-Z  or  the  MapcatSF,  the  Company  will  not  have  the
resources necessary to continue its business in its current form. If the Company is unable to establish and maintain adequate sales, marketing and distribution
capabilities  or  enter  into  or  maintain  agreements  with  third  parties  to  do  so,  it  may  be  unable  to  successfully  commercialize  its  products.  The  Company
believes  it  is  creating  an  efficient  commercial  organization,  taking  advantage  of  outsourcing  options  where  prudent  to  maximize  the  effectiveness  of  its
commercial expenditures. However, it may not be able to correctly judge the size and experience of the sales and marketing force and the scale of distribution
necessary  to  be  successful.  Establishing  and  maintaining  sales,  marketing,  and  distribution  capabilities  are  expensive  and  time-consuming.  Such  expenses
may be disproportionate compared to the revenues the Company may be able to generate on sales of Lumega-Z or licensing fees or sales of the MapcatSF. If
this occurs, it will have an adverse impact on operations and the Company’s ability to fund any future development.

15

 
 
 
 
 
 
 
 
 
 
 
 
 
 
We have limited experience in developing medical foods and medical devices, and we may be unable to commercialize some of the products we develop.

Development  and  commercialization  of  medical  foods  and  medical  devices  involves  a  lengthy  and  complex  process.  We  have  limited  experience  in
developing  products  and  have  only  one  commercialized  product  on  the  market,  our  medical  food  Lumega-Z.  In  addition,  no  one  has  ever  developed  or
commercialized  a  medical  device  like  the  MapcatSF,  and  we  cannot  assure  you  that  it  is  possible  to  further  develop  or  successfully  commercialize  the
MapcatSF or that we will be successful in doing so.

Even if we develop products for commercial use, these products may not be accepted by the medical and pharmaceutical marketplaces or be capable of being
offered at prices that will enable us to become profitable. We cannot assure you that our products will be approved by regulatory authorities, if required, or
ultimately prove to be useful for commercial markets, meet applicable regulatory standards, or be successfully marketed.

We and our suppliers and manufacturers are subject to a number of existing laws, regulations and industry initiatives and the regulatory environment of
the healthcare industry is continuing to change. If it is determined that we or our suppliers or manufacturers are not in compliance with the laws and
regulations to which we are subject, our business, financial condition and results of operations may be adversely affected.

As a participant in the healthcare industry, our operations and relationships, and those of our customers, are regulated by a number of federal, state and local
governmental entities and our products must be capable of being used by our customers in a manner that complies with those laws and regulations. Inability
of our customers to do so could affect the marketability of our products or our compliance with our customer contracts, or even expose us to direct liability on
a  theory  that  we  had  assisted  our  customers  in  a  violation  of  healthcare  laws  or  regulations.  Because  of  our  business  relationships  with  physicians  and
professional healthcare providers, and since our product, Lumega-Z is believed to be a medical food and our product, the MapcatSF, is a medical device, a
number  of  regulations  are  implicated.  For  example,  from  the  FDA’s  perspective,  a  drug  cures,  treats,  or  mitigates  the  effects  or  symptoms  of  a  specific
disease. A medical food manages a specific disease or condition for which distinctive nutritional requirements, based on recognized scientific principles, are
established by medical evaluation. While we believe Lumega-Z is a medical food, if the FDA was to determine Lumega-Z to be a drug, the Company and the
product would be subject to additional FDA regulation. Similarly, while we believe the MapcatSF is a safe medical device, with a very low potential risk of
injury to a patient, we believe the MapcatSF is correctly classified as a Class I medical device, which does not require any premarket approval. If, however,
the  FDA  were  to  determine  that  the  MapcatSF  is  a  Class  II  medical  device,  the  Company  and  the  product  would  be  subject  to  additional  regulatory
requirements.

In  addition,  we  cannot  anticipate  how  changes  in  regulations  or  determinations  by  regulatory  agencies  may  evolve.  Thus,  application  of  many  state  and
federal  regulations  to  our  business  operations  is  uncertain.  Further,  there  are  federal  and  state  fraud  and  abuse  laws,  including  anti-kickback  laws  and
limitations on physician referrals and laws related to off-label promotion of prescription drugs that may or may not be directly or indirectly applicable to our
operations and relationships or the business practices of our customers. It is possible that a review of our business practices or those of our customers by
courts or regulatory authorities could result in a determination that may adversely affect us. In addition, the healthcare regulatory environment may change in
a way that restricts our existing operations or our growth. The healthcare industry is expected to continue to undergo significant changes for the foreseeable
future,  which  could  have  an  adverse  effect  on  our  business,  financial  condition  and  results  of  operations.  We  cannot  predict  the  effect  of  possible  future
legislation and regulation.

16

 
 
 
 
 
 
 
 
 
 
We may be subject to fines, penalties, injunctions and other sanctions if we are deemed to be promoting the use of our products as a drug.

Our business and future growth depend on the development, use and ultimate sale of products that are subject to FDA regulation, clearance and approval.
Under the U.S. Federal Food, Drug, and Cosmetic Act and other laws, we are prohibited from promoting our products for treatment of a condition or disease.
This means that we may not make claims about the usefulness or effectiveness or expected outcome of use of our products for any particular condition or
disease and may not proactively discuss or provide information on the use of our products, except as allowed by the FDA.

There  is  a  risk  that  the  FDA  or  other  federal  or  state  law  enforcement  authorities  could  determine  that  the  nature  and  scope  of  our  sales  and  marketing
activities may constitute the promotion of our products for use as a drug in violation of applicable law. We also face the risk that the FDA or other regulatory
authorities might pursue enforcement based on past activities that we have discontinued or changed, including sales activities, arrangements with institutions
and doctors, educational and training programs and other activities.

Government investigations are typically expensive, disruptive, burdensome and generate negative publicity. If our promotional activities are found to be in
violation of applicable law or if we agree to a settlement in connection with an enforcement action, we would likely face significant fines and penalties and
would likely be required to substantially change our sales, promotion and educational activities. In addition, were any enforcement actions against us or our
senior officers to arise, we could be excluded from participation in U.S. government healthcare programs such as Medicare and Medicaid.

Lumega-Z may not qualify as a medical food as defined by the FDA.

If the FDA makes a determination that Lumega-Z should not be defined as a medical food (and does not qualify as a drug), we would need to relabel and
rebrand that product. While reclassification and the subsequent relabeling and rebranding would be an added cost to operations, it would not change the use or
effectiveness of Lumega-Z. Although, Management believes it is unlikely the FDA would make such a determination, there is a chance that certain physicians
may choose not to recommend Lumega-Z to their patients or that certain consumers may choose not to buy Lumega-Z if it is not classified as a medical food.
While  there  is  no  insurance  coverage  for  Lumega-Z  as  a  medical  food,  if  insurance  companies  would  otherwise  pay  for  Lumega-Z  because  of  it  being  a
medical food, a determination by the FDA that Lumega-Z should not be defined as a medical food could limit or eliminate such potential insurance coverage
which might adversely impact the sales of Lumega-Z.

A key part of our business strategy is to establish collaborative relationships to commercialize and develop our product candidates. We may not succeed in
establishing  and  maintaining  collaborative  relationships,  which  may  significantly  limit  our  ability  to  develop  and  commercialize  our  products
successfully, if at all.

A  key  part  of  our  business  strategy  is  to  establish  collaborative  relationships  to  commercialize  and  fund  development  of  our  product  candidates.  We  are
currently a party to several collaborative relationships. The Illinois College of Optometry, for example, has included the MapcatSF prototype in its curriculum
to instruct students on how to measure the macular pigment. The New York Eye and Ear Infirmary is currently evaluating Lumega-Z on glaucoma patients.
The Rosenberg School of Optometry at the University of the Immaculate Word is conducting research on patients with a MapcatSF prototype. Moreover, our
Science  Advisory  Board,  each  member  of  whom  is  displayed  on  the  Company  website,  includes  world  renowned  experts  in  macular  carotenoids  who  are
developing the peer review markets by conducting research and furthering the understanding of the relevance of the macular pigment in ocular health. Our
Medical  Advisors  includes  thought-leading  clinicians  in  retina,  glaucoma  and  the  anterior  segment  of  the  eye,  providing  guidance  on  understanding  the
clinical applications of Lumega-Z and the MapcatSF and understanding the market opportunities and assisting in driving our strategic goals.

While we believe that these collaborative relationships help further validate the MapcatSF and Lumega-Z, these relationships are not material to the Company
because  none  of  these  relationships  is  exclusive,  there  are  many  potential  collaborative  partners  available,  and  the  Company  is  free  to  enter  into  other
collaborative relationships as needed. No sales of Lumega-Z are generated directly from Illinois College of Optometry because the MapcatSF is part of its
teaching  curriculum,  not  used  for  direct  patient  care.  However,  the  other  collaborative  relationships,  as  a  result  of  using  the  MapcatSF  on  patients,
periodically put patients on Lumega-Z if a physician determines it appropriate to do so. The majority of sales of Lumega-Z primarily come from clinicians
outside of these collaborative relationships.

17

 
 
 
 
 
 
 
 
 
 
 
 
 
We believe that we may not be able to negotiate collaborations on acceptable terms, if at all, and if we do enter into collaborations, these collaborations may
not  be  successful.  Our  current  and  future  success  depends  in  part  on  our  ability  to  enter  into  successful  collaboration  arrangements.  If  we  are  unable  to
establish and maintain collaborative relationships on acceptable terms or to successfully transition terminated collaborative agreements, we may have to delay
or discontinue further development of one or more of our product candidates, undertake development and commercialization activities at our own expense or
find alternative sources of capital. Consequently, if we are unable to enter into, maintain or extend successful collaborations, our business may be harmed.

Our long-term success may depend upon the successful development and commercialization of products other than Lumega-Z and the MapcatSF.

Our long-term viability and growth may depend upon the successful development and commercialization of products other than Lumega-Z and the MapcatSF.
Product  development  and  commercialization  is  very  expensive  and  involves  a  high  degree  of  risk.  Only  a  small  number  of  research  and  development
programs result in the commercialization of a product. Product development is a complex, time-consuming and expensive process. If we fail to adequately
manage the research, development, execution and regulatory aspects of new product development we may fail to launch new products altogether.

Government  agencies  may  establish  usage  guidelines  that  directly  apply  to  our  products  or  proposed  products  or  change  legislation  or  regulations  to
which we are subject.

Government usage guidelines typically address matters such as usage and dose, among other factors. Application of these guidelines could limit the use of our
products  and  products  that  we  may  develop.  In  addition,  there  can  be  no  assurance  that  government  regulations  applicable  to  our  products  or  proposed
products or the interpretation thereof will not change and thereby prevent the marketing of some or all of our products for a period of time or permanently.
The FDA’s policies may change and additional government regulations may be enacted that could modify, prevent, delay or change the regulatory approval
required  of  our  products.  We  cannot  predict  the  likelihood,  nature  or  extent  of  adverse  government  regulation  that  may  arise  from  future  legislation  or
administrative action, either in the U.S. or in other countries.

Patent litigation is common in the pharmaceutical and biopharmaceutical industries. Any litigation or claim against us may cause us to incur substantial
costs, and could place a significant strain on our financial resources, divert the attention of management from our business and harm our reputation.

While we are not a pharmaceutical or a biopharmaceutical company, as a health sciences company, our medical foods or our medical device may come into
competition with products in the medical foods and related industries, such as pharmaceuticals, biologics or dietary supplements. There has been substantial
litigation  in  the  pharmaceutical  and  biopharmaceutical  industries  with  respect  to  the  manufacture,  use  and  sale  of  new  products  that  are  the  subject  of
conflicting patent rights. For the most part, these lawsuits relate to the validity, enforceability and infringement of patents. We expect that we will rely upon
patents, trade secrets, know-how, continuing technological innovations and licensing opportunities to develop and maintain our competitive position. We may
find it necessary to initiate claims to defend our intellectual property rights as a result. Other parties may have issued patents or be issued patents that may
prevent the sale of our products or know-how or require us to license such patents and pay significant fees or royalties to produce our products. In addition,
future  patents  may  issue  to  third  parties  which  our  technology  may  infringe.  Because  patent  applications  can  take  many  years  to  issue,  there  may  be
applications now pending of which we are unaware that may later result in issued patents that our products may infringe.

18

 
 
 
 
 
 
 
 
 
 
 
Intellectual property litigation, regardless of outcome, is expensive and time-consuming, and could divert management’s attention from our business and have
a material negative effect on our business, operating results or financial condition. If such a dispute were to be resolved against us, we may be required to pay
substantial damages, including treble damages and attorney’s fees to the party claiming infringement if we were to be found to have willfully infringed a third
party’s  patent.  We  may  also  have  to  develop  non-infringing  technology,  stop  selling  any  products  we  develop,  cease  using  technology  that  contains  the
allegedly infringing intellectual property or enter into royalty or license agreements that may not be available on acceptable or commercially practical terms,
if at all. Our failure to develop non-infringing technologies or license the proprietary rights on a timely basis could harm our business. Modification of any
products we develop or development of new products thereafter could require us to become subject to other requirements of the FDA and other regulatory
bodies,  which  could  be  time-consuming  and  expensive.  In  addition,  parties  making  infringement  claims  may  be  able  to  obtain  an  injunction  that  would
prevent us from selling any products we develop, which could harm our business.

Our competitors may develop products similar to Lumega-Z, and we may therefore need to modify or alter our business strategy, which may delay the
achievement of our goals.

Competitors may develop products with similar characteristics to Lumega-Z. Such similar products marketed by larger competitors could hinder our efforts to
penetrate the market. As a result, we may be forced to modify or alter our business and regulatory strategy and sales and marketing plans, as a response to
changes in the market, competition and technology limitations, among others. Such modifications may pose additional delays in achieving our goals.

If we are unable to develop our own sales, marketing and distribution capabilities, or if we are not successful in contracting with third parties for these
services on favorable terms, or at all, revenues from any products we develop could be limited.

We  currently  have  limited  sales,  marketing  and  distribution  capabilities.  To  commercialize  our  products  successfully,  we  have  to  develop  more  robust
capabilities internally or collaborate with third parties that can perform these services for us. In the process of commercializing our products, we may not be
able to hire the necessary experienced personnel and build sales, marketing and distribution operations capable of successfully launching new products and
generating sufficient product revenues. In addition, establishing such operations takes time and involves significant expense.

If  we  decide  to  enter  into  co-promotion  or  other  licensing  arrangements  with  third  parties,  we  may  be  unable  to  identify  acceptable  partners  because  the
number of potential partners is limited and because of competition from others for similar alliances with potential partners. Even if we are able to identify one
or  more  acceptable  partners,  we  may  not  be  able  to  enter  into  any  partnering  arrangements  on  favorable  terms,  or  at  all.  If  we  enter  into  any  partnering
arrangements, our revenues are likely to be lower than if we marketed and sold our products ourselves.

In addition, any revenues we receive would depend upon our partners’ efforts which may not be adequate due to lack of attention or resource commitments,
management turnover, and change of strategic focus, further business combinations or other factors outside of our control. Depending upon the terms of our
agreements,  the  remedies  we  have  against  an  under-performing  partner  may  be  limited.  If  we  were  to  terminate  the  relationship,  it  may  be  difficult  or
impossible to find a replacement partner on acceptable terms, or at all.

If we cannot compete successfully for market share against other companies, we may not achieve sufficient product revenues and our business will suffer.

The market for our products and product candidates is characterized by competition and technological advances. If our products are unable to capture and
maintain market share, we may not achieve sufficient product revenues and our business will suffer.

We  will  compete  for  market  share  against  fully  integrated  medical  food  and  medical  device  companies  or  other  companies  that  develop  products
independently  or  collaborate  with  larger  pharmaceutical  companies,  academic  institutions,  government  agencies  and  other  public  and  private  research
organizations. In addition, many of these competitors, either alone or together with their collaborative partners, have substantially greater capital resources,
larger research and development staffs and facilities, and greater financial resources than we do, as well as significantly greater experience in:

·
·

developing medical foods and medical devices;
conducting product testing and studies;

19

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
·
·
·

complying with regulatory requirements;
formulating and manufacturing products; and
launching, marketing, distributing and selling products.

Our competitors may:

·
·
·
·

develop and patent processes or products earlier than we will;
develop and commercialize products that are less expensive or more efficient than our products;
comply with regulatory requirements more rapidly than us; or
improve  upon  existing  technological  approaches  or  develop  new  or  different  approaches  that  render  our  technology  or  products  obsolete  or
uncompetitive.

If we are unable to compete successfully against current or future competitors, we may be unable to obtain market acceptance for any product candidates that
we create, which could prevent us from generating revenues or achieving profitability and could cause the market price of our common stock to decline.

We may be unsuccessful in expanding our product distribution outside the United States.

To  the  extent  we  begin  to  offer  our  products  outside  the  United  States,  we  expect  that  we  may  be  dependent  on  third-party  distribution  relationships.
Distributors  may  not  commit  the  necessary  resources  to  market  and  sell  our  products  to  the  level  of  our  expectations.  If  distributors  do  not  perform
adequately,  or  we  are  unable  to  locate  distributors  in  particular  geographic  areas,  our  ability  to  realize  long-term  international  revenue  growth  would  be
materially adversely affected.

Additionally, our products may require regulatory clearances and approvals from jurisdictions outside the United States. We expect that we will be subject to
and required to comply with local regulatory requirements before selling our products in those jurisdictions. We are not certain that we will be able to obtain
these clearances or approvals or compliance requirements on a timely basis, or at all.

Manufacturing risks and inefficiencies may adversely affect our ability to produce products.

We  engage  third  parties  to  manufacture  our  products  in  sufficient  quantities  and  on  a  timely  basis,  while  maintaining  product  quality  and  acceptable
manufacturing costs and complying with regulatory requirements. In determining the required quantities of our products and the manufacturing schedule, we
must make significant judgments and estimates based on historical experience, inventory levels, current market trends and other related factors. Because of
the inherent nature of estimates, there could be significant differences between our estimates and the actual amounts of products we require. If we are unable
to obtain from one or more of our vendors the needed materials or components that meet our specifications on commercially reasonable terms, or at all, we
may not be able to meet the demand for our products. We have not arranged for alternate suppliers, and it may be difficult to find alternate suppliers in a
timely manner and on terms acceptable to us.

Security breaches and other disruptions could compromise our information and expose us to liability, which would cause our business and reputation to
suffer.

In the ordinary course of our business, we collect and store sensitive data, including intellectual property, our proprietary business information and that of our
customers and business partners, including personally identifiable information of our customers, some of which is stored on our network and some of which
is stored with our third-party E-commerce vendor. Despite our security measures, our information technology and infrastructure may be vulnerable to attacks
by hackers or breached due to operator error, malfeasance or other disruptions. Any such breach could compromise our network and the information stored
there could be accessed, publicly disclosed, lost or stolen. Any such access, disclosure or other loss of information could result in legal claims or proceedings,
liability  under  laws  that  protect  the  privacy  of  personal  information,  disrupt  our  operations,  and  damage  our  reputation,  which  could  adversely  affect  our
business.

20

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Our  products  and  facility  and  the  facilities  of  our  manufacturers  are  subject  to  federal  laws  and  regulations  and  certain  requirements  in  the  State  of
California. Failure to comply with any law or regulation could result in penalties and restrictions on our manufacturers’ ability to manufacture and our
ability to distribute products. If any such action were to be imposed, it could have a material adverse effect on our business and results of operations.

Although medical foods do not require pre-market approval by the FDA, manufacturers of medical foods must be registered with the FDA under a provision
promulgated  by  the  Public  Health  Security  and  Bioterrorism  Preparedness  and  Response  Act  of  2002  (the “Bioterrorism Act”).  Manufacturers  of  medical
foods are subject to periodic inspection by the FDA. The manufacture of our medical foods is outsourced in its entirety to a third-party manufacturer. We are
evaluating additional manufacturers for selection as second source or back-up providers. Our medical foods have not been reviewed by the FDA. There is no
certainty that the FDA will favorably review our medical food products or our manufacturers’ facilities. If the outcome of an inspection is negative or if we or
our manufacturers fail to comply with any law or regulation, we could be subject to penalties and restrictions on our manufacturers’ ability to manufacture
and distribute products. Any such action may result in a material adverse effect on our business and results of operations. For a more complete discussion of
the laws and regulations to which we are subject, see the section of this report titled “Description of Business - Government Regulation.”

A significant portion of the Company’s billings and revenues are derived from the sale of a single product.

In  the  years  ended  December  31,  2016  and  2015,  the  Company  derived  100%  of  its  revenues  from  the  sale  of  Lumega-Z®.  While  we  continue  to  see  an
increasing demand for Lumega-Z from our customers, we cannot assure you that the demand will continue. A decline in sales of Lumega-Z to our customers
may have an immediate adverse effect on our financial results.

All  of  the  Company’s  billings  and  revenues  are  derived  from  a  limited  number  of  customers  and  the  loss  of  any  one  or  more  of  them  may  have  an
immediate adverse effect on our financial results.

In the years ended December 31, 2016 and 2015, the Company’s billings were derived from a limited number of individual customers. The Company does not
receive volume commitments from its customers. Customers may stop purchasing our products with little or no warning. Loss of customers may have an
immediate adverse effect on our financial results.

If we are forced to reduce our prices, our business, financial condition and results of operations may suffer.

We  may  be  subject  to  pricing  pressures  with  respect  to  our  future  sales  arising  from  various  sources,  including  practices  of  health  insurance  companies,
healthcare providers and competition in the marketplace. If our pricing experiences significant downward pressure, our business could be less profitable and
our results of operations may be adversely affected. In addition, because cash from sales funds our working capital requirements, reduced profitability could
require us to raise additional capital to support our operations.

If we are unable to successfully introduce new products or fail to keep pace with medical advances and developments, our business, financial condition
and results of operations may be adversely affected.

The  successful  implementation  of  our  business  model  depends  on  our  ability  to  adapt  to  evolving  technologies  and  industry  standards  and  introduce  new
products and services. We cannot assure you that we will be able to introduce new products on schedule, or at all, or that such products will achieve market
acceptance.  Moreover,  competitors  may  develop  competitive  products  that  could  adversely  affect  our  results  of  operations. A  failure  by  us  to  introduce
planned products or other new products or to introduce these products on schedule may have an adverse effect on our business, financial condition and results
of operations.

If we cannot adapt to changing technologies, our products and services may become obsolete, and our business could suffer. Because the healthcare industry
is characterized by rapid technological change, we may be unable to anticipate changes in our current and potential customers’ requirements that could make
our existing technology obsolete. Our success will depend, in part, on our ability to continue to enhance our existing products, develop new technology that
addresses the needs of our prospective customers, license leading technologies and respond to technological advances and emerging industry standards and
practices on a timely and cost-effective basis. The development of our proprietary technology entails significant technical and business risks. We may not be
successful in using new technologies effectively or adapting our proprietary technology to evolving customer requirements or emerging industry standards,
and, as a result, our business may suffer.

21

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
If customers do not accept our products, or delay in deciding whether to recommend our products and services, our business, financial condition and
results of operations may be adversely affected.

Our business model depends on our ability to sell our products. Acceptance of our products requires physicians to use our MapcatSF to measure the macular
protective pigment in their patients’ eyes and understand and appreciate the benefits of Lumega-Z in order to recommend it to their patients. We cannot assure
you  that  physicians  will  integrate  our  products  into  their  treatment  plans  or  patient  recommendations.  Achieving  market  acceptance  for  our  products  and
services will require substantial sales and marketing efforts and the expenditure of significant financial and other resources to create awareness and demand
by participants in the healthcare industry. If we fail to achieve broad acceptance of our products by physicians, and other healthcare industry participants or if
we fail to position our products as an ocular health remedy, our business, financial condition and results of operations may be adversely affected.

If our principal suppliers fail or are unable to perform their contracts with us, we may be unable to meet our commitments to our customers. As a result,
our reputation and our relationships with our customers may be damaged and our business and results of operations may be adversely affected.

We  currently  purchase  all  our  medical  food  ingredients  and  products  from  three  vendors  –  one  for  carotenoids,  one  for  Omega  3,  and  one  for  all  other
supplements. These companies are subject to FDA regulation and they are responsible for compliance with current Good Manufacturing Practices. Although
our agreements provide that our suppliers will abide by the FDA manufacturing requirements, we cannot control their compliance. If they fail to comply with
FDA manufacturing requirements, the FDA could prevent our vendors from manufacturing our ingredients and products. Although we believe that there are a
number of other sources of supply of ingredients and manufacturers of medical food products, if these suppliers are unable to perform under our agreements,
particularly at certain critical times such as when we add new physician clients that will require a large production of one or more products, we may be unable
to meet our commitments to our customers. If this were to happen, our reputation as well as our relationships with our customers may suffer and our business
and results of operations may be adversely affected. We are evaluating several additional manufacturers for selection as second source or back-up providers.

If  we  incur  costs  exceeding  our  insurance  coverage  in  lawsuits  that  are  brought  against  us  in  the  future,  it  would  be  expected  to  adversely  affect  our
business, financial condition and results of operations.

If we were to become a defendant in any lawsuits involving the manufacture and sale of our products and if our insurance coverage were inadequate to satisfy
these liabilities, it would be expected to have an adverse effect on our business, financial condition and results of operations.

If  we  are  deemed  to  infringe  on  the  proprietary  rights  of  third  parties,  we  could  incur  unanticipated  expense  and  be  prevented  from  providing  our
products and services.

We  could  be  subject  to  intellectual  property  infringement  claims  as  the  number  of  our  competitors  grows  and  if  our  products  or  the  functionality  of  our
products overlap with patents of our competitors. While we do not believe that we have infringed or are infringing on any proprietary rights of third parties,
we cannot assure you that infringement claims will not be asserted against us or that those claims will be unsuccessful. We could incur substantial costs and
diversion of management resources defending any infringement claims whether or not such claims are ultimately successful. Furthermore, a party making a
claim against us could secure a judgment awarding substantial damages, as well as injunctive or other equitable relief that could effectively block our ability
to provide products or services. In addition, we cannot assure you that licenses for any intellectual property of third parties that might be required for our
products or services will be available on commercially reasonable terms, or at all.

22

 
 
 
 
 
 
 
 
 
 
 
 
Our business depends on our intellectual property rights, and if we are unable to protect them, our competitive position may suffer.

Our business plan is predicated on our proprietary technology. Accordingly, protecting our intellectual property rights is critical to our continued success and
our ability to maintain our competitive position. Our goal is to protect our proprietary rights through a combination of patent, trademark, trade secret and
copyright law, confidentiality agreements and technical measures. We generally enter into non-disclosure agreements with our employees and consultants and
limit  access  to  our  trade  secrets  and  technology.  We  cannot  assure  you  that  the  steps  we  have  taken  will  prevent  misappropriation  of  our  technology.
Misappropriation of our intellectual property would have an adverse effect on our competitive position.

The Company has one issued patent and one pending patent application related to its products. Our success, competitive position, and future revenues will
depend, in part, on our ability to obtain and maintain patent protection for our products, methods, processes, and other technologies; to preserve our trade
secrets; to obtain trademarks for our name, logo and products; to prevent third parties from infringing our proprietary rights; and to operate without infringing
the proprietary rights of third parties. To counter infringement or unauthorized use by third parties, we may be required to file infringement claims, which can
be expensive and time-consuming. If we infringe the rights of third parties, we could be prevented from selling our products, forced to pay damages, and
forced to incur substantial costs in defending litigations.

The  patent  process  is  subject  to  numerous  risks  and  uncertainties,  and  there  can  be  no  assurance  that  we  will  be  successful  in  protecting  our  products  by
obtaining and defending patents. These risks and uncertainties include the following:

·

·

·

Claims of issued patents, and the claims of any patents which may be issued in the future and be owned by or licensed to the Company may be
challenged by third parties, resulting in patents being deemed invalid, unenforceable, or narrowed in scope, a third party may circumvent any such
issued patents, or such issued patents may not provide any significant commercial protection against competing products.

Our competitors, many of which have substantially greater resources than we do and many of which have made significant investments in competing
technologies,  may  seek,  or  may  already  have  obtained,  patents  that  will  limit,  interfere  with,  or  eliminate  our  ability  to  make,  use,  and  sell  our
potential products either in the United States or in international markets.

The legal systems of some foreign countries do not encourage the aggressive enforcement of patents, and countries other than the United States may
have less restrictive patent laws than those upheld by United States courts, allowing foreign competitors the ability to exploit these laws to create,
develop, and market competing products. Thus, the Company’s foreign patents may not be enforceable to the same extent as the counterpart U.S.
patents.

In addition, the USPTO, and patent offices in other jurisdictions have often required that patent applications concerning pharmaceutical and/or biotechnology-
related inventions be limited or narrowed substantially to cover only the specific innovations exemplified in the patent application, thereby limiting the scope
of protection against competitive challenges. Thus, even if we or any of our licensors are able to obtain patents, the patents may be substantially narrower
than anticipated.

Our  business  depends  in  part  on  and  will  continue  to  depend  in  part  on  our  ability  to  establish  and  maintain  additional  strategic  collaborative
relationships. Our failure to establish and maintain these relationships could make it more difficult to expand the reach of our products, which may have
a material adverse effect on our business.

To be successful, we must continue to maintain our existing strategic relationships, such as our relationship with our vendors who manufacture our medical
food products. We also must continue to establish additional strategic relationships with healthcare leaders. This is critical to our success because we believe
that  these  relationships  contribute  towards  our  ability  to  extend  the  reach  of  our  products  and  services  to  a  larger  number  of  physicians,  professional
healthcare providers and physician groups and to other participants in the healthcare industry; develop and deploy new products and services; enhance the
Lumega-Z® brand in the U.S. and potentially the Lumega-Z brand internationally; and generate additional revenue and cash flows. Entering into strategic
relationships  is  complicated  because  strategic  partners  may  decide  to  compete  with  us  in  some  or  all  of  our  markets.  In  addition,  we  may  not  be  able  to
maintain or establish relationships with key participants in the healthcare industry if we conduct business with their competitors.

23

 
 
 
 
 
 
 
 
 
 
 
 
 
 
We must attract quality management in order to manage our growth. Failure to do so may result in slower expansion.

In  order  to  support  the  growth  of  our  business,  we  will  need  to  expand  our  senior  management  team.  There  is  no  assurance  that  we  will  be  capable  of
attracting quality managers and integrating those individuals into our management system. Without experienced and talented management, the growth of our
business may be adversely impacted.

Competition for qualified employees is intense, and we may not be able to attract and retain the highly skilled employees we need to support our business.
Without  skilled  employees,  the  quality  of  our  product  development  and  services  could  diminish  and  the  growth  of  our  business  may  be  slowed,  which
could have a material adverse effect on our business, financial condition and results of operations.

Our ability to provide high-quality products and services to our clients depends, in large part, upon our employees’ experience and expertise. We must attract
and retain highly qualified personnel with a deep understanding of the pharmaceutical and healthcare information technology industries. In addition, we will
invest significant time and expense in training our employees, increasing their value to clients as well as to competitors who may seek to recruit them, which
will increase the cost of replacing them. If we fail to retain our employees, the quality of our product development and services could diminish and the growth
of our business may be slowed. This may have a material adverse effect on our business, financial condition and results of operations.

If we lose the services of our Chief Executive Officer and other key personnel, we may be unable to replace them, and our business, financial condition
and results of operations may be adversely affected.

Our success largely depends on the continued skills, experience, efforts and policies of our management and other key personnel and our ability to continue to
attract, motivate and retain highly qualified employees. In particular, the services of Michael Favish, our founder, President and Chief Executive Officer, are
integral to the execution of our business strategy. We believe that the loss of the services of Mr. Favish could adversely affect our business, financial condition
and results of operations. We cannot assure you that Mr. Favish or our other executive officers will continue to provide services to the Company. We do not
maintain key man insurance for any of our key personnel.

Our failure to compete successfully could cause our revenue or market share to decline.

The  market  for  our  products  and  services  is  competitive  and  is  characterized  by  rapidly  evolving  industry  standards,  technology  and  user  needs  and  the
frequent  introduction  of  new  products  and  services.  Some  of  our  competitors,  which  include  major  pharmaceutical  companies  with  alternatives  to  our
products, may be more established, benefit from greater name recognition and have substantially greater financial, technical and marketing resources than us.
We  compete  on  the  basis  of  several  factors,  including  distribution  of  products,  reputation,  scientific  validity,  reliability,  client  service,  price,  and  industry
expertise  and  experience.  There  can  be  no  assurance  that  we  will  be  able  to  compete  successfully  against  current  and  future  competitors  or  that  the
competitive pressures that we face will not materially adversely affect our business, financial condition and results of operations.

Our future success depends upon our ability to grow, and if we are unable to manage our growth effectively, we may incur unexpected expenses and be
unable to meet our customers’ requirements.

We will need to expand our operations if we successfully achieve market acceptance for our products and services. We cannot be certain that our systems,
procedures, controls and existing space will be adequate to support expansion of our operations. Our future operating results will depend on the ability of our
officers  and  key  employees  to  manage  changing  business  conditions  and  to  implement  and  improve  our  technical,  administrative,  financial  control  and
reporting systems. We may not be able to expand and upgrade our systems and infrastructure to accommodate these increases. Difficulties in managing any
future  growth  could  have  a  significant  negative  impact  on  our  business,  financial  condition  and  results  of  operations  because  we  may  incur  unexpected
expenses and be unable to meet our customers’ requirements.

24

 
 
 
 
 
 
 
 
 
 
 
 
 
 
We may consider acquiring other companies or product lines in an effort to expand our business in exchange for cash and/or stock of the Company (or a
combination therof), which may not be successful or which may cause dilution to investors.

The  Company  will  also  consider  acquiring  other  companies  or  product  lines  that  may  be  complementary  or  supplementary  as  part  of  our  future  efforts  to
expand the business, which acquisitions could be for cash, stock or a combination thereof. In either event, there is no guarantee that any such acquisition will
be successful or that an acquired company’s products, operations or corporate culture will mesh with our Company, integrate well, or that any economies of
scale will be realized. In addition, any such transaction that involves the Company’s stock would cause dilution to investors. The Company has signed a non-
binding Letter of Intent to acquire VectorVision, Inc. in a stock for stock acquisition. There can be no assurance that even if this acquisition is completed, the
acquisition will be successful. In addition, any such transaction that involves cash would result in a reallocation of funds on hand that would be needed to
support an acquired company or acquired product line.

In order to expand our business into additional states, we may need to comply with regulatory requirements specific to such states and there can be no
assurance that we will be able to initially meet such requirements or that we will be able to maintain compliance on an on-going basis.

While we believe our product, Lumega-Z®, to be a medical food and not a drug, it is only available under the supervision of a physician. While it is not
available  in  pharmacies,  we  are  mindful  that  the  act  of  physicians  prescribing,  particularly  if  conducted  across  state  lines,  could  potentially  be  subject  to
certain  pharmacy  regulations.  Each  state  has  its  own  regulations  concerning  physician  dispensing,  restrictions  on  the  corporate  practice  of  medicine,  anti-
kickback and false claims. In addition, each state has a board of pharmacy that regulates the sale and distribution of drugs and other therapeutic agents. Some
states require a physician to obtain a license to dispense prescription products. While we do not believe these pharmacy requirements are applicable should a
pharmacy board or medical board determine otherwise, there can be no assurance that we will be able to comply with the regulations of particular states into
which  we  may  expand  or  that  we  will  be  able  to  maintain  compliance  with  the  states  in  which  we  currently  distribute  our  products.  We  currently  have
Lumega-Z  customers  in  California,  Massachusetts,  Connecticut,  New  York,  Pennsylvania,  New  Jersey,  Georgia,  North  Carolina,  South  Carolina,  Florida,
Kentucky, Tennessee, Kansas, Indiana, Illinois, Minnesota, Oklahoma, Texas, New Mexico, Mississippi, Idaho, Utah, Nevada, Arizona, Washington, Hawaii
and  Alberta,  Canada.  Our  inability  to  maintain  compliance  with  the  regulations  of  California  and  these  other  jurisdictions,  or  expand  our  business  into
additional states may adversely affect our results of operations.

Our Bylaws have an exclusive forum for adjudication of disputes provision which limits the forum to the Delaware Court of Chancery for certain actions
against the Company.

Article  XI  of  our  Bylaws  dictates  that  the  Delaware  Court  of  Chancery  is  the  sole  and  exclusive  forum  for  certain  actions  including  derivative  action  or
proceeding brought on behalf of the Company; an action asserting a breach of fiduciary duty owed by an officer, a director, employee or to the shareholders of
the  Company;  any  claim  arising  under  Delaware  corporate  law;  and  any  action  asserting  a  claim  governed  by  the  internal  affairs  doctrine.  This  means  a
shareholder has a limited forum in which to bring one of the above causes of action, which can be inconvenient for the shareholder.

A Delaware corporation is allowed to mandate in its corporate governance documents a chosen forum for the resolution of state law based shareholder class
actions, derivative suits and other intra-corporate disputes. The Company’s management believes limiting state law based claims to Delaware will provide the
most appropriate outcomes as the risk of another forum misapplying Delaware law is avoided. Delaware courts have a well-developed body of case law and
limiting the forum will preclude costly and duplicative litigation and avoids the risk of inconsistent outcomes. It also means a shareholder’s ability to bring a
claim in a forum it believes is favorable to shareholders in disputes with directors, officers or other employees is limited and may discourage shareholders
from  bringing  such  claims.  Additionally,  Delaware  Chancery  Courts  can  typically  resolve  disputes  on  an  accelerated  schedule  when  compared  to  other
forums.

25

 
 
 
 
 
 
 
 
 
 
 
Risks Related to Our Industry

Any failure to comply with all applicable federal and state confidentiality requirements for the protection of patient information may result in fines and
other liabilities, which may adversely affect our results of operations.

When  a  physician  recommends  our  medical  food,  Lumega-Z,  to  a  patient  we  typically  receive  an  order  from  the  customer,  but  we  do  not  usually  receive
medical information. As part of the operation of our business, it is possible, however, that during communication with customers or with physicians we might
receive  patient-identifiable  medical  information.  The  Health  Insurance  Portability  and  Accountability  Act  of  1996,  Pub.  L.  No.  104-191  (“HIPAA”),  the
Health Information Technology for Economic and Clinical Health Act, Title XIII of the American Recovery and Reinvestment Act of 2009 (the “HITECH
Act”), and related regulations promulgated by the Secretary (“HIPAA Regulations”) grant a number of rights to individuals as to their identifiable confidential
medical information (called “Protected Health Information”) and restrict the use and disclosure of Protected Health Information. Failure to comply with these
confidentiality requirements may result in penalties and sanctions. In addition, certain state laws may impose independent obligations upon us with respect to
patient-identifiable medical information. Moreover, various new laws relating to the acquisition, storage and transmission of patient medical information have
been proposed at both the federal and state level. Any failure to comply may result in fines and other liabilities, which may adversely affect our results of
operations.

Congress enacted significant prohibitions against physician self-referrals in the Omnibus Budget Reconciliation Act of 1993. This law, commonly referred to
as  “Stark  II,”  applies  to  physician  dispensing  of  outpatient  prescription  drugs  that  are  reimbursable  by  Medicare  or  Medicaid.  Our  products  are  neither
prescription  drugs  nor  are  they  reimbursable  under  any  federal  program  at  present.  Stark  II,  however,  includes  an  exception  for  the  provision  of  in-office
ancillary services, including a physician’s dispensing of outpatient prescription drugs, provided that the physician meets specified requirements. We believe
that the physicians who use our medical device, the MapcatSF, or recommend our medical food, Lumega-Z, to their patients are aware of these requirements,
but we do not monitor their compliance and have no assurance that the physicians are in material compliance with Stark II. If it were determined that the
physicians  who  use  our  medical  device  or  prescribe  medical  foods  purchased  from  us  were  not  in  compliance  with  Stark  II,  it  could  potentially  have  an
adverse effect on our business, financial condition and results of operations.

The federal anti-kickback statute applies to Medicare, Medicaid and other state and federal programs. At present, our products are not prescription drugs, nor
are  they  reimbursable  under  any  federal  program.  The  federal  anti-kickback  statute  prohibits  the  solicitation,  offer,  payment  or  receipt  of  remuneration  in
return  for  referrals  or  the  purchase,  or  in  return  for  recommending  or  arranging  for  the  referral  or  purchase,  of  goods,  including  drugs,  covered  by  the
programs. The federal anti-kickback statute provides a number of statutory exceptions and regulatory “safe harbors” for particular types of transactions. We
believe  that  our  arrangements  with  our  customers  are  in  material  compliance  with  the  anti-kickback  statute  and  relevant  safe  harbors.  Many  states  have
similar fraud and abuse laws, and we believe that we are in material compliance with those laws. At present, we do not participate in any federal programs
and  our  products  are  not  reimbursed  by  Medicare,  Medicaid  or  any  other  state  or  federal  program.  If,  however,  that  changes  in  the  future  and  it  were
determined  that  we  were  not  in  compliance  with  the  federal  anti-kickback  statute,  we  could  be  subject  to  liability,  and  our  operations  could  be  curtailed.
Moreover, if the activities of our customers or other entity with which we have a business relationship were found to constitute a violation of the federal anti-
kickback  law  and  we,  as  a  result  of  the  provision  of  products  or  services  to  such  customer  or  entity,  were  found  to  have  knowingly  participated  in  such
activities, we could be subject to sanction or liability under such laws, including civil and/or criminal penalties, as well as exclusion from government health
programs.  As  a  result  of  exclusion  from  government  health  programs,  neither  products  nor  services  could  be  provided  to  any  beneficiaries  of  any  federal
healthcare program.

26

 
 
 
 
 
 
 
 
 
Increased government involvement in healthcare could adversely affect our business.

U.S. healthcare system reform under the Medicare Prescription Drug, Improvement and Modernization Act of 2003, the Patient Protection and Affordable
Care Act of 2010 and other initiatives at both the federal and state level, could increase government involvement in healthcare, lower reimbursement rates and
otherwise  change  the  business  environment  of  our  customers  and  the  other  entities  with  which  we  have  a  business  relationship.  While  no  federal  price
controls are included in the Medicare Prescription Drug, Improvement and Modernization Act, any legislation that reduces physician incentives to dispense
medications  in  their  offices  could  adversely  affect  physician  acceptance  of  our  products.  We  cannot  predict  whether  or  when  future  healthcare  reform
initiatives at the federal or state level or other initiatives affecting our business will be proposed, enacted or implemented or what impact those initiatives may
have on our business, financial condition or results of operations. Our customers and the other entities with which we have a business relationship could react
to  these  initiatives  and  the  uncertainty  surrounding  these  proposals  by  curtailing  or  deferring  investments,  including  those  for  our  products. Additionally,
government regulation could alter the clinical workflow of physicians, hospitals and other healthcare participants, thereby limiting the utility of our products
and services to existing and potential customers and curtailing broad acceptance of our products and services. Additionally, new safe harbors to the federal
Anti-Kickback Statute and corresponding exceptions to such law may alter the competitive landscape.

Risks Related to Our Common Stock

We are an “emerging growth company” and we have elected to comply with certain reduced reporting and disclosure requirements which could make our
common stock less attractive to investors.

We are an “emerging growth company,” as defined in the Jumpstart Our Business Startups Act of 2012, (the “JOBS Act”). For as long as we continue to be an
emerging  growth  company,  we  have  elected  to  take  advantage  of  exemptions  from  various  reporting  requirements  that  are  applicable  to  other  public
companies that are not emerging growth companies, including (1) not being required to comply with the auditor attestation requirements of Section 404 of the
Sarbanes-Oxley  Act  of  2002,  which  we  refer  to  as  the  Sarbanes-Oxley  Act,  (2)  reduced  disclosure  obligations  regarding  executive  compensation  in  this
Annual Report and our periodic reports and proxy statements and (3) exemptions from the requirements of holding a nonbinding advisory vote on executive
compensation and stockholder approval of any golden parachute payments not previously approved. In addition, as an emerging growth company, we are only
required  to  provide  two  years  of  audited  financial  statements  and  two  years  of  selected  financial  data  in  this  Annual  Report.  As  a  result  of  these  reduced
reporting and disclosure requirements our financial statements may not be comparable to SEC registrants not classified as emerging growth companies. We
may be an emerging growth company for up to five years, although circumstances could cause us to lose that status earlier, including if the market value of
our common stock held by non-affiliates exceeds $700.0 million before that time or if we have total annual gross revenue of $1.0 billion or more during any
fiscal year before that time, in which cases we would no longer be an emerging growth company as of the following December 31 or, if we issue more than
$1.0 billion in non-convertible debt during any three-year period before that time, we would immediately cease to be an emerging growth company. Even
after we no longer qualify as an emerging growth company, we may still qualify as a “smaller reporting company” which would allow us to take advantage of
many of the same exemptions from disclosure requirements, including not being required to comply with the auditor attestation requirements of Section 404
of  the  Sarbanes-Oxley  Act  and  reduced  disclosure  obligations  regarding  executive  compensation  in  our  periodic  reports  and  proxy  statements.  We  cannot
predict  if  investors  will  find  our  common  stock  less  attractive  because  we  may  rely  on  these  exemptions.  If  some  investors  find  our  common  stock  less
attractive as a result, there may be a less active trading market for our common stock and our stock price may be more volatile.

Our independent registered public accounting firm will not be required to formally attest to the effectiveness of our internal control over financial reporting
until the later of our second annual report or the first annual report required to be filed with the Commission following the date we are no longer an “emerging
growth company” as defined in the JOBS Act.  We cannot assure you that there will not be material weaknesses or significant deficiencies in our internal
controls in the future.

Under the JOBS Act, emerging growth companies can also delay adopting new or revised accounting standards until such time as those standards apply to
private companies. We have elected to avail ourselves of this exemption from new or revised accounting standards and, therefore, will not be subject to the
same new or revised accounting standards as other SEC registrants that are not emerging growth companies.

27

 
 
 
 
 
 
 
 
 
 
 
Investors may find our common stock less attractive as a result of our election to utilize these exemptions, which could result in a less active trading market
for our common stock and/or the market price of our common stock may be more volatile.

Our directors and executive officers beneficially own a significant number of shares of our common stock.  Their interests may conflict with our outside
stockholders, who may be unable to influence management and exercise control over our business.

As of the date of this Annual Report, our executive officers and directors beneficially own approximately 37.3% of our shares of common stock.  As a result,
our executive officers and directors may be able to: affect the election or defeat the election of our directors, amend or prevent amendment to our certificates
of incorporation or bylaws, effect or prevent a merger, sale of assets or other corporate transaction, and control the outcome of any other matter submitted to
the shareholders for vote. Accordingly, our outside stockholders may be unable to influence management and exercise control over our business.

We do not intend to pay cash dividends to our stockholders, so you will not receive any return on your investment in our Company prior to selling your
interest in the Company.

We have never paid any dividends to our common stockholders and do not foresee doing so as a public company. We currently intend to retain any future
earnings for funding growth and, therefore, do not expect to pay any cash dividends in the foreseeable future. If we determine that we will pay cash dividends
to the holders of our common stock, we cannot assure that such cash dividends will be paid on a timely basis. The success of your investment in the Company
will likely depend entirely upon any future appreciation.  As a result, you will not receive any return on your investment prior to selling your shares in our
Company and, for the other reasons discussed in this “Risk Factors” section, you may not receive any return on your investment even when you sell your
shares in our Company.

We require additional capital to support our current operations, and this capital has not been readily available.

We require additional debt or equity financing to fund our current operations, including, but not limited to, working capital. As a publicly-owned reporting
company,  we  expect  that  it  may  facilitate  our  ability  to  secure  additional  funds.  Our  limited  operating  history  makes  it  difficult  to  evaluate  our  current
business  model  and  future  prospects.  Accordingly,  investors  should  consider  our  prospects  in  light  of  the  costs,  uncertainties,  delays  and  difficulties
frequently encountered by companies in the early stages of development, as we have, in fact, encountered. Potential investors should carefully consider the
risks and uncertainties that a new company with a limited operating history and with limited funds, will face. In particular, potential investors should consider
that there is a significant risk that we will not be able to:

implement or execute our current business plan, which may or may not be sound;

·
· maintain our anticipated management and advisory team; and
·

raise sufficient funds in the capital markets to effectuate our business plan.

If we raise additional funds through further issuances of equity or convertible debt securities, our existing shareholders could suffer significant dilution, and
any new equity securities we issue could have rights, preferences and privileges superior to those of holders of our existing capital stock. Any debt financing
secured by us in the future could involve restrictive covenants relating to our capital raising activities and other financial and operational matters, which may
make it more difficult for us to obtain additional capital and to pursue business opportunities. In addition, we may not be able to obtain additional financing
on terms favorable to us, if at all. If we are unable to obtain adequate financing or financing on terms satisfactory to us, when we require it, our ability to
continue to support our current operations and to respond to business challenges would be significantly limited. If we cannot access the capital necessary to
support our business, we would be forced to curtail our business activities or even shut down operations. If we cannot execute any one of the foregoing or
similar matters relating to our business, the business may fail, in which case you would lose the entire amount of your investment in the Company.

28

 
 
 
 
 
 
 
 
 
 
 
 
 
The obligations associated with being a public company require significant resources and management attention, which may divert from our business
operations.

We are subject to the reporting requirements of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and The Sarbanes-Oxley Act of 2002
(“SOX”).  The Exchange Act requires that we file annual, quarterly and current reports with respect to our business and financial condition, proxy statement,
and other information. SOX requires, among other things, that we establish and maintain effective internal controls and procedures for financial reporting.
 Our Chief Executive Officer and Chief Accounting Officer need to certify that our disclosure controls and procedures are effective in ensuring that material
information we are required to disclose in reports that we file or submit under the Exchange Act is recorded, processed, summarized and reported within the
time periods specified in the SEC’s rules and forms. We will need to hire additional financial reporting, internal controls and other financial personnel in order
to develop and implement appropriate internal controls and reporting procedures.  As a result, we will incur significant legal, accounting and other expenses.
 Furthermore, the need to establish the corporate infrastructure demanded of a public company may divert management’s attention from implementing our
growth strategy, which could prevent us from improving our business, results of operations and financial condition. We have made, and will continue to make,
changes  to  our  internal  controls  and  procedures  for  financial  reporting  and  accounting  systems  to  meet  our  reporting  obligations  as  a  public  company.
However, the measures we take may not be sufficient to satisfy our obligations as a public company. In addition, we cannot predict or estimate the amount of
additional  costs  we  may  incur  in  order  to  comply  with  these  requirements.  We  anticipate  that  these  costs  will  materially  increase  our  selling,  general  and
administrative expenses.

Section  404  of  the  Sarbanes-Oxley  Act  requires  annual  management  assessments  of  the  effectiveness  of  our  internal  control  over  financial  reporting.    In
connection  with  the  implementation  of  the  necessary  procedures  and  practices  related  to  internal  control  over  financial  reporting,  we  may  identify
deficiencies.    If  we  are  unable  to  comply  with  the  internal  controls  requirements  of  SOX,  then  we  may  not  be  able  to  obtain  the  independent  account
certifications required by that act, which may preclude us from keeping our filings with the SEC current, and interfere with the ability of investors to trade our
securities and our shares to be quoted or our ability to list our shares on any national securities exchange.

If we fail to establish and maintain an effective system of internal controls, we may not be able to report our financial results accurately or prevent fraud.
 Any  inability  to  report  and  file  our  financial  results  accurately  and  timely  could  harm  our  reputation  and  adversely  impact  the  trading  price  of  our
common stock.

Effective  internal  controls  are  necessary  for  us  to  provide  reliable  financial  reports  and  prevent  fraud.    If  we  cannot  provide  reliable  financial  reports  or
prevent  fraud,  we  may  not  be  able  to  manage  our  business  as  effectively  as  we  would  if  an  effective  control  environment  existed,  and  our  business  and
reputation with investors may be harmed.  With each prospective acquisition, we will conduct whatever due diligence is necessary or prudent to assure us that
the acquisition target can comply with the internal controls requirements of the Sarbanes-Oxley Act.  Notwithstanding our diligence, certain internal controls
deficiencies may not be detected.  As a result, any internal control deficiencies may adversely affect our financial condition, results of operations and access
to  capital.    We  have  not  performed  an  in-depth  analysis  to  determine  if  historical  undiscovered  failures  of  internal  controls  exist,  and  may  in  the  future
discover areas of our internal controls that need improvement.

Risks Related to Our Securities

Public company compliance may make it more difficult to attract and retain officers and directors.

The  Sarbanes-Oxley  Act  and  rules  implemented  by  the  SEC  have  required  changes  in  corporate  governance  practices  of  public  companies.  As  a  public
company, these rules and regulations increase our compliance costs and make certain activities more time consuming and costly. As a public company, these
rules and regulations may make it more difficult and expensive for us to maintain our director and officer liability insurance and we may be required to accept
reduced policy limits and coverage or incur substantially higher costs to obtain the same or similar coverage. As a result, it may be more difficult for us to
attract and retain qualified persons to serve on our Board of Directors or as executive officers, and to maintain insurance at reasonable rates, or at all.

29

 
 
 
 
 
 
 
 
 
 
 
 
Our stock price may be volatile and you may not be able to resell your shares at or above the purchase price.

The market price of our common stock is likely to be highly volatile and could fluctuate widely in price in response to various factors, many of which are
beyond our control, including the following:

·
·
·
·
·
·
·
·
·
·
·
·

·
·

our ability to execute our business plan;
changes in our industry;
competitive pricing pressures;
our ability to obtain working capital financing;
additions or departures of key personnel;
sales of our common stock;
operating results that fall below expectations;
regulatory developments;
economic and other external factors;
period-to-period fluctuations in our financial results;
the public’s response to press releases or other public announcements by us or third parties, including filings with the SEC;
changes in financial estimates or ratings by any securities analysts who follow our common stock, our failure to meet these estimates or failure of
those analysts to initiate or maintain coverage of our common stock;
the development and sustainability of an active trading market for our common stock; and
any future sales of our common stock by our officers, directors and significant stockholders.

In  addition,  the  securities  markets  have  from  time  to  time  experienced  significant  price  and  volume  fluctuations  that  are  unrelated  to  the  operating
performance of particular companies. These market fluctuations may also materially and adversely affect the market price of our common stock.

Our shares of common stock are not publicly traded and there can be no assurance that there will be an active market for our shares of common stock in
the future.

Our shares of common stock are not currently publicly traded and timing for the commencement of trading is uncertain. There can be no assurance that there
will be an active market for our shares of common stock in the future. If we are able to establish a public market for our securities, the market liquidity will be
dependent on the perception of our operating business, among other things.  We intend to take certain steps including utilizing investor awareness campaigns
and firms, press releases, road shows and conferences to increase awareness of our business. Any steps that we might take to bring us to the awareness of
investors may require that we compensate consultants with cash and/or stock. There can be no assurance that there will be any awareness generated or the
results of any efforts will result in any impact on our trading volume. Consequently, investors may not be able to liquidate their investment or liquidate it at a
price that reflects the value of the business, and trading may be at an inflated price relative to the performance of the Company due to, among other things, the
availability of sellers of our shares.

If an active market should develop, the price may be highly volatile. If there is a low price for our shares of common stock, many brokerage firms or clearing
firms may not be willing to effect transactions in the securities or accept our shares for deposit in an account.  Many lending institutions will not permit the
use of low priced shares of common stock as collateral for any loans.

We are subject to penny stock regulations and restrictions and you may have difficulty selling shares of our common stock.

Our  common  stock  will  be  subject  to  the  provisions  of  Section  15(g)  and  Rule  15g-9  of  the  Exchange  Act,  commonly  referred  to  as  the  “penny  stock
rules.”  Section 15(g) sets forth certain requirements for transactions in penny stock, and Rule 15g-9(d) incorporates the definition of “penny stock” that is
found in Rule 3a51-1 of the Exchange Act.  The SEC generally defines a penny stock to be any equity security that has a market price less than $5.00 per
share, subject to certain exceptions. We will be subject to the SEC’s penny stock rules.

30

 
 
 
 
 
 
 
 
 
 
 
 
 
Since our common stock will be deemed to be penny stock, trading in the shares of our common stock will be subject to additional sales practice requirements
on broker-dealers who sell penny stock to persons other than established customers and accredited investors. “Accredited investors” are persons with assets in
excess of $1,000,000 (excluding the value of such person’s primary residence) or annual income exceeding $200,000 or $300,000 together with their spouse.
For  transactions  covered  by  these  rules,  broker-dealers  must  make  a  special  suitability  determination  for  the  purchase  of  such  security  and  must  have  the
purchaser’s written consent to the transaction prior to the purchase. Additionally, for any transaction involving a penny stock, unless exempt from the rules
require the delivery, prior to the first transaction of a risk disclosure document, prepared by the SEC, relating to the penny stock market.  A broker-dealer also
must disclose the commissions payable to both the broker-dealer and the registered representative and current quotations for the securities.  Finally, monthly
statements must be sent disclosing recent price information for the penny stocks held in an account and information to the limited market in penny stocks.
Consequently, these rules may restrict the ability of broker-dealer to trade and/or maintain a market in our common stock and may affect the ability of the
Company’s stockholders to sell their shares of common stock.

There can be no assurance that our shares of common stock will qualify for exemption from the penny stock rules. In any event, even if our common stock
was exempt from the penny stock rules, we would remain subject to Section 15(b)(6) of the Exchange Act, which gives the SEC the authority to restrict any
person from participating in a distribution of penny stock if the SEC finds that such a restriction would be in the public interest.

ITEM 1B. UNRESOLVED STAFF COMMENTS

Not applicable.

ITEM 2. PROPERTIES

The  Company’s  address  is  15150  Avenue  of  Science,  Suite  200,  San  Diego,  California  92128.  Our  telephone  number  is  858-605-9055.  The  Company’s
offices are rented under a six-year lease for approximately 9,605 square feet of space at a current rental of $9,893 per month.

ITEM 3. LEGAL PROCEEDINGS

From time to time, the Company may become involved in litigation relating to claims arising out of its operations in the normal course of business. No legal
proceedings, government actions, administrative actions, investigations or claims are currently pending or threatened against us or involve the Company.

ITEM 4. MINE SAFETY DISCLOSURES

Not applicable.

31

 
 
 
 
 
 
 
 
 
 
 
 
 
 
PART II

ITEM  5.  MARKET  FOR  REGISTRANT’S  COMMON  EQUITY,  RELATED  STOCKHOLDER  MATTERS  AND  ISSUER  PURCHASES  OF
EQUITY SECURITIES

Market Information

There is currently no public market for our shares of common stock. We intend to seek a listing of our common stock on the OTCQB maintained by OTC
Markets Group, however, we cannot assure you that our application will be approved or be certain of the timing for commencement of trading.

Dividend Policy

Guardion Health Sciences, Inc. has not declared nor paid any cash dividend on our common stock, and we currently intend to retain future earnings, if any, to
finance the expansion of our business, and we do not expect to pay any cash dividends in the foreseeable future.  The decision whether to pay cash dividends
on our common stock will be made by our Board of Directors, in their discretion, and will depend on our financial condition, results of operations, capital
requirements and other factors that our Board of Directors considers significant.

ITEM 6. SELECTED FINANCIAL DATA

Not applicable.

ITEM 7. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Presentation of Information

As  used  in  this Annual  Report  on  Form  10-K,  the  terms  “we,”  “us”  “our”  and  the  “Company”  mean  Guardion  Health  Sciences,  Inc.  unless  the  context
requires  otherwise.  The  following  discussion  and  analysis  should  be  read  in  conjunction  with  our  audited  financial  statements  and  the  related  notes  that
appear elsewhere in this report. All dollar amounts in this registration statement refer to U.S. dollars unless otherwise indicated.

Overview

Guardion Health Sciences, Inc. (the “Company” or “we”) was formed in December 2009 in California as a limited liability company under the name P4L
Health Sciences, LLC and we subsequently changed our name to Guardion Health Sciences, LLC. On June 30, 2015, we converted from a California limited
liability company to a Delaware corporation, changing our name to Guardion Health Sciences, Inc.

We are a specialty health sciences company formed to develop, formulate and distribute condition-specific medical foods with an initial medical food product
on the market under the brand name Lumega-Z® that replenishes and restores the macular protective pigment. A depleted macular protective pigment is a
modifiable  risk  factor  for  retina  based  diseases  such  as  age-related  macular  degeneration  (“AMD”),  computer  vision  syndrome  (“CVS”)  and  diabetic
retinopathy. Additional research has also shown a depleted macular protective pigment to be a biomarker for neurodegenerative diseases such as Alzheimer’s
and dementia. We have had limited commercial operations to date, and have primarily been engaged in research and development.

We have also developed a proprietary medical device called the MapcatSF® that accurately measures the macular pigment optical density (“MPOD”). We
invented our own proprietary patented technology embodied in the MapcatSF. On November 8, 2016, the USPTO issued patent number 9,486,136 for the
MapcatSF invention. Using the MapcatSF to measure the MPOD allows one to monitor the increase in the density of the macular protective pigment after
taking Lumega-Z. The MapcatSF is a non-mydriatic, non-invasive device that accurately measures the MPOD, the lens optical density and lens equivalent
age, thereby creating an evidence-based protocol that is shared with the patient. A non-mydriatic device is one that does not require dilation of the pupil for it
to function. The MapcatSF is intended to be the first device using a patented “single fixation” process and “automatic lens density correction” that produces
accurate serialized data.

32

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Lumega-Z has a patent-pending formula that replenishes and restores the macular protective pigment simultaneously delivering critical and essential nutrients
to the eye. Formulated by Dr. Sheldon Hendler in 2010, modifications were made over a two-year period to improve the taste and method of delivery. We
believe that there is an increasing level of acceptance of medical foods as a primary therapy by patients and healthcare providers to treat pain syndromes,
sleep and cognitive disorders, obesity, hypertension, and viral infection. In clinical practice, medical foods are being prescribed as both a standalone therapy
and as an adjunct therapy to low doses of commonly prescribed drugs. We believe that medical foods will continue to grow in importance over the coming
years.

By combining our MapcatSF medical device and Lumega-Z medical food, we have developed, based on Management’s knowledge of the industry, the only
reliable two-pronged, evidence-based protocol for replenishing and restoring the macular protective pigment and increasing overall retinal health.

Recent Developments

On  March  1,  2017,  the  Company  entered  into  a  non-binding  letter  of  intent  (“LOI”)  with  Vector  Vision,  Inc.,  a  Delaware  corporation  (“VectorVision”),
whereby the parties set forth an outline of the terms and conditions pursuant to which the Company would acquire all of the outstanding shares of stock of
VectorVision  in  exchange  for  a  to  be  determined  number  of  shares  of  common  stock  of  the  Company.  VectorVision  specializes  in  the  standardization  of
contrast sensitivity, glare sensitivity, low contrast acuity, and ETDRS acuity vision testing. Its patented standardization system provides the practitioner or
researcher with the ability to delineate very small changes in visual capability, either as compared to the population or from visit to visit. VectorVision’s CSV-
1000 device is considered the standard of care for clinical trials. Upon closing of the transaction, VectorVision would become a wholly-owned subsidiary of
the Company. The Company believes the acquisition of VectorVision would expand the Company’s technical portfolio and further establish the Company’s
position  at  the  forefront  of  early  detection,  intervention  and  monitoring  of  a  range  of  eye  diseases.  The  transaction  is  subject  to  significant  conditions
precedent to closing, including, but not limited to, the satisfactory completion of due diligence, the determination of the amount of purchase consideration, the
negotiation of definitive transaction documents, the completion of an audit of VectorVision’s financial statements, and other matters, no later than the June 30,
2017 expiration date of the LOI.

Going Concern

The financial statements have been prepared assuming the Company will continue as a going concern. The Company has utilized cash in operating activities
of $1,653,574 and $1,139,758 during the years ended December 31, 2016 and 2015, respectively, and had a total stockholders’ deficiency of $345,574 and
$1,227,550 as of December 31, 2016 and 2015, respectively. The Company expects to continue to incur net losses and negative operating cash flows in the
near-term. As a result, management has concluded that there is substantial doubt about the Company’s ability to continue as a going concern within one year
of the date that the consolidated financial statements are issued.

The Company’s auditors have also included explanatory language in their opinion that there is substantial doubt about the Company’s ability to continue as a
going concern. The financial statements do not include any adjustments to reflect the possible future effects on the recoverability and classification of assets
or the amounts and classifications of liabilities that may result from the possible inability of the Company to continue as a going concern.

We will continue to incur significant expenses for commercialization activities related to our lead product Lumega-Z, the MapcatSF medical device, and with
respect  to  efforts  to  build  our  infrastructure.  Development  and  commercialization  of  medical  foods  and  medical  devices  involves  a  lengthy  and  complex
process.  Additionally,  our  long-term  viability  and  growth  may  depend  upon  the  successful  development  and  commercialization  of  products  other  than
Lumega-Z  and  the  MapcatSF.  We  are  continuing  attempts  to  raise  additional  debt  and/or  equity  capital  to  fund  future  operations,  but  there  can  be  no
assurances that we will be able to secure such additional financing in the amounts necessary to fully fund our operating requirements on acceptable terms or at
all.  If  we  are  unable  to  access  sufficient  capital  resources  on  a  timely  basis,  we  may  be  forced  to  reduce  or  discontinue  our  technology  and  product
development programs and curtail or cease operations. 

33

 
 
 
 
 
 
 
 
 
 
 
 
Recent Accounting Pronouncements

In  May  2014,  the  Financial  Accounting  Standards  Board  (“FASB”)  issued  Accounting  Standards  Update  No.  2014-09  (ASU  2014-09),  Revenue  from
Contracts with Customers. ASU 2014-09 will eliminate transaction- and industry-specific revenue recognition guidance under current GAAP and replace it
with  a  principle  based  approach  for  determining  revenue  recognition.  ASU  2014-09  will  require  that  companies  recognize  revenue  based  on  the  value  of
transferred  goods  or  services  as  they  occur  in  the  contract.  ASU  2014-09  also  will  require  additional  disclosure  about  the  nature,  amount,  timing  and
uncertainty of revenue and cash flows arising from customer contracts, including significant judgments and changes in judgments and assets recognized from
costs incurred to obtain or fulfill a contract. Based on the FASB’s Exposure Draft Update issued on April 29, 2015, and approved in July 2015, Revenue from
Contracts With Customers (Topic 606): Deferral of the Effective Date, ASU 2014-09 is now effective for reporting periods beginning after December 15,
2017, with early adoption permitted only as of annual reporting periods beginning after December 15, 2016, including interim reporting periods within that
reporting period. Entities will be able to transition to the standard either retrospectively or as a cumulative-effect adjustment as of the date of adoption. The
adoption of ASU 2014-09 is not expected to have any impact on our financial statement presentation or disclosures.

In February 2016, the FASB issued Accounting Standards Update No. 2016-02 (ASU 2016-02), Leases (Topic 842). ASU 2016-02 requires a lessee to record
a right-of-use asset and a corresponding lease liability, initially measured at the present value of the lease payments, on the balance sheet for all leases with
terms longer than 12 months, as well as the disclosure of key information about leasing arrangements. ASU 2016-02 requires recognition in the statement of
operations  of  a  single  lease  cost,  calculated  so  that  the  cost  of  the  lease  is  allocated  over  the  lease  term,  generally  on  a  straight-line  basis.  ASU  2016-02
requires classification of all cash payments within operating activities in the statement of cash flows. Disclosures are required to provide the amount, timing
and uncertainty of cash flows arising from leases. A modified retrospective transition approach is required for lessees for capital and operating leases existing
at, or entered into after, the beginning of the earliest comparative period presented in the financial statements, with certain practical expedients available. ASU
2016-02 is effective for fiscal years beginning after December 15, 2018, including interim periods within those fiscal years. Early application is permitted.
The Company has not yet evaluated the impact of the adoption of ASU 2016-02 on the Company’s financial statement presentation or disclosures.

In  March  2016,  the  FASB  issued  Accounting  Standards  Update  No.  2016-09  (ASU  2016-09),  Compensation  -  Stock  Compensation  (Topic  718):
Improvements  to  Employee  Share-Based  Payment  Accounting.  ASU  2016-09  requires,  among  other  things,  that  all  income  tax  effects  of  awards  be
recognized in the statement of operations when the awards vest or are settled. ASU 2016-09 also allows for an employer to repurchase more of an employee's
shares than it can today for tax withholding purposes without triggering liability accounting and allows for a policy election to account for forfeitures as they
occur. ASU 2016-09 is effective for fiscal years beginning after December 15, 2016, including interim periods within those fiscal years. Early adoption is
permitted  for  any  entity  in  any  interim  or  annual  period.  The  adoption  of  ASU  2016-09  is  not  expected  to  have  any  impact  on  the  Company’s  financial
statement presentation or disclosures.

Management does not believe that any other recently issued, but not yet effective, authoritative guidance, if currently adopted, would have a material impact
on the Company’s financial statement presentation or disclosures.

Concentration of Risk

Cash balances are maintained at large, well-established financial institutions. At times, cash balances may exceed federally insured limits. The Company has
never experienced any losses related to these balances. Insurance coverage limits are $250,000 per depositor at each financial institution. All cash balances
were fully insured at December 31, 2016 and 2015.

34

 
 
 
 
 
 
 
 
 
 
 
Critical Accounting Policies and Estimates

Our financial statements have been prepared in conformity with accounting principles generally accepted in the United States of America (“GAAP”). The
preparation of the financial statements in conformity with GAAP requires management to make certain estimates and assumptions that affect the reported
amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and reported amounts of expenses
during the reporting period. Actual results could differ from those estimates. Our financial statements included herein include all adjustments, consisting of
only normal recurring adjustments, necessary to present fairly the Company's financial position, results of operations and cash flows.

The following critical accounting policies affect the more significant judgments and estimates used in the preparation of the Company’s consolidated financial
statements.

Revenue Recognition

Revenue is recognized on the sale of a product when the risk of loss transfers to our customers, and collection of the receivable is reasonably assured, which
generally occurs when the product is shipped. A product is not shipped without an order from the customer and credit acceptance procedures performed.

Patent Costs

We hold one issued patent and one pending patent application for our MapcatSF and Lumega-Z products. Due to the significant uncertainty associated with
the successful development of one or more commercially viable products based on our research efforts and any related patent applications, all patent costs,
including  patent-related  legal  fees,  filing  fees  and  other  costs,  including  internally  generated  costs,  are  expensed  as  incurred.  During  the  years  ended
December 31, 2016 and 2015, patent costs were $30,942 and $26,407, respectively, and are included in total research and development costs in the statements
of operations.

Research and Development

Research and development costs consist primarily of fees paid to consultants and outside service providers, patent fees and costs, and other expenses relating
to the acquisition, design, development and testing of the Company’s medical foods and related products. Research and development costs are expensed as
incurred.

Convertible Notes Payable

When conventional convertible debt is issued with detachable warrants, the proceeds from issuance are allocated to the two instruments based on their relative
fair values. This method is generally appropriate if debt is issued with any other freestanding instrument that is classified in equity.

When the convertible debt instrument includes both detachable instruments such as warrants, and a beneficial conversion option, the proceeds of issuance are
allocated  among  the  convertible  instrument  and  the  other  detachable  instruments  based  on  their  relative  fair  values  as  indicated  above,  and  the  amount
allocated to the convertible instrument is further analyzed to determine if the embedded conversion option has intrinsic value. If the conversion features of
conventional convertible debt provide for a rate of conversion that is below market value, then the conversion option has intrinsic value and this feature is
characterized  as  a  beneficial  conversion  feature  (“BCF”).  We  calculate  an  effective  conversion  price  based  on  the  fair  value  allocated  to  the  convertible
instrument divided by the number of conversion shares based upon the conversion terms of the instrument. The resulting calculation or effective conversion
price is used to measure the intrinsic value, if any, of the embedded conversion option. Stated differently, intrinsic value is calculated at the commitment date
as the difference between the conversion price (effective or otherwise) and the fair value of the common stock or other securities into which the security is
convertible, multiplied by the number of shares into which the security is convertible.

If the intrinsic value of the BCF is greater than the proceeds allocated to the convertible instrument, the amount of the discount assigned to the BCF is limited
to the amount of the proceeds allocated to the convertible instrument. We record a BCF as a debt discount and in those circumstances, the convertible debt
will be recorded net of the discount related to the BCF. The Company amortizes the discount to interest expense over the life of the debt using the effective
interest rate method or the straight-line method, as an approximation of effective interest amortization.

35

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Stock-Based Compensation

We periodically issue stock-based compensation to officers, directors, and other consultants for services rendered. Such issuances vest and expire according to
terms established at the issuance date.

Stock-based payments to officers and directors, and to employees in the future which will include grants of employee stock options, are recognized in the
financial statements based on their fair values. Stock option grants, which are generally time vested, will be measured at the grant date fair value and charged
to operations on a straight-line basis over the vesting period. The fair value of stock options is determined utilizing the Black-Scholes option-pricing model,
which is affected by several variables, including the risk-free interest rate, the expected dividend yield, the expected life of the equity award, the exercise
price of the stock option as compared to the fair market value of the common stock on the grant date and the estimated volatility of the common stock over
the term of the equity award.

The risk-free interest rate is based on the U.S. Treasury yield curve in effect at the time of grant. Until we have established a trading market for our common
stock, estimated volatility is based on the average historical volatilities of comparable public companies in a similar industry. The expected dividend yield is
based on the current yield at the grant date; we have never declared or paid dividends on our common stock and have no plans to do so for the foreseeable
future.

The fair value of members’ units or common stock was determined based on management’s judgment. In order to assist management in calculating such fair
value, we retained a third-party valuation firm in determining the value of our Company. The third-party valuation firm’s input was utilized in determining the
related per unit or share valuations of our equity used at December 31, 2016 and 2015. Management used a valuation of $1.00 per share for the period January
1, 2015 to September 30, 2016, and a valuation of $0.88 per share for the period October 1, 2016 to December 31, 2016 in its fair value calculations for the
years ended December 31, 2016 and 2015, respectively, based on various inputs, including valuation reports prepared by the third-party valuation firm for
December 31, 2016 and 2015. The fully diluted per share equivalent price is lower in 2016 than in 2015 due to the dilutive effect of the issuance of common
shares as compensation during the period. There are numerous acceptable ways to estimate company value, including using net tangible assets, a market-
based  approach,  or  discounted  cash  flows.  We  considered  alternative  methods  and  concluded  that  due  to  the  lack  of  suitably  comparable  market  data,  the
discounted cash flows method was the most appropriate. A discounted cash flows (i.e. free cash flows to equity) methodology was applied by the third-party
valuation firm using multiple years of balance sheet and income statement projections along with the following primary assumptions:

Discount rate
Risk free rate
Rate of return
Sustainable growth rate
Company survival probability
Liquidation value

  Year Ended December 31,

2016

2015

16%   
2.48%   
16%   
5%   
65%   
  $
0 

16%
2.27%
16%
5%
63%
0 

  $

The Company accounts for stock option and warrant grants issued and vesting to non-employees in accordance with the authoritative guidance of the FASB
whereas the value of the stock compensation is based upon the measurement date as determined at either a) the date at which a performance commitment is
reached, or b) at the date at which the necessary performance to earn the equity instruments is complete. Non-employee stock-based compensation charges
generally are amortized over the vesting period on a straight-line basis. In certain circumstances where there are no future performance requirements by the
non-employee, option grants are immediately vested and the total stock-based compensation charge is recorded in the period of the measurement date. We
recognize stock compensation expense on stock or unit purchases at a price less than fair value, and for fully-vested stock issued to consultants and other
service providers, for the excess of fair value of the stock or units over the price paid for the stock or units.

36

 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
 
 
 
 
We  recognize  the  fair  value  of  stock-based  compensation  within  our  statements  of  operations  with  classification  depending  on  the  nature  of  the  services
rendered. We issue new shares to satisfy stock option exercises.

During  the  years  ended  December  31,  2016  and  2015,  we  recognized  aggregate  stock-compensation  expense  of  $1,962,311  and  $4,885,589,  respectively,
based upon stock prices ranging from $0.88 to $1.14 per share, of which $1,811,990 and $4,419,959 was recorded in general and administrative expense,
$145,214  and  $119,429  was  recorded  in  sales  and  marketing  expense,  and  $5,107  and  $346,201  was  recorded  in  research  and  development  expense,
respectively.

Income Taxes

We were a limited liability company prior to June 30, 2015 and taxed as a pass-through entity whereby substantially all income tax attributes were passed
through to the individual members except the minimum state income tax and an LLC fee based on revenues. As of June 30, 2015, we became a corporation
subject to U.S. federal income taxes and California state income taxes.

We  currently  account  for  income  taxes  under  an  asset  and  liability  approach  for  financial  accounting  and  reporting  for  income  taxes.  Accordingly,  we
recognize deferred tax assets and liabilities for the expected impact of differences between the financial statements and the tax basis of assets and liabilities.

We  account  for  uncertainties  in  income  tax  law  under  a  comprehensive  model  for  the  financial  statement  recognition,  measurement,  presentation  and
disclosure of uncertain tax positions taken or expected to be taken in income tax returns as prescribed by GAAP. The tax effects of a position are recognized
only if it is “more-likely-than-not” to be sustained by the taxing authority as of the reporting date. If the tax position is not considered “more-likely-than-not”
to be sustained, then no benefits of the position are recognized. As of December 31, 2016, we had not recorded any liability for uncertain tax positions. In
subsequent periods, any interest and penalties related to uncertain tax positions will be recognized as a component of income tax expense.

We record a valuation allowance to reduce our deferred tax assets to the amount that is more likely than not to be realized. In the event we determine that we
would be able to realize our deferred tax assets in the future in excess of its recorded amount, an adjustment to the deferred tax assets would be credited to
operations in the period such determination was made. Likewise, should we determine that we would not be able to realize all or part of our deferred tax
assets in the future, an adjustment to the deferred tax assets would be charged to operations in the period such determination was made.

Plan of Operations

General Overview

Based on the availability of sufficient funding, we intend to increase our commercialization activities and:

·

·
·

·
·

further the commercial production of our MapcatSF, starting with the manufacture of at least ten new units for sale or lease to our customers and for
use in our internal clinics;
expand our domestic sales and marketing efforts, which include revamping our web site and new promotional materials;
increase  production  of  Lumega-Z  as  is  necessary  to  support  the  additional  sales  resulting  from  the  deployment  of  additional  MapcatSF  units  and
increased marketing and promotional activity;
commence certain FDA electrical safety testing of the MapcatSF; and
increase our focus on intellectual property protection and strategy.

37

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
The  FDA  and  other  regulatory  bodies  require  electronic  medical  devices  to  comply  with  IEC  60601  standards.  The  International  Electrical  Commission
(“IEC”)  established  technical  standards  for  the  safety  and  effectiveness  of  medical  electrical  equipment.  Adherence  to  these  standards  is  required  for
commercialization of electrical medical equipment. As a medical device powered by electricity, the MapcatSF will need to undergo testing to demonstrate
compliance  with  the  IEC  60601  standards.  This  testing  is  typically  conducted  by  a  Nationally  Recognized  Testing  Laboratory  (“NRTL”),  which  is  an
independent  laboratory  recognized  by  the  Occupational  Safety  and  Health  Administration  (“OSHA”)  to  test  products  to  the  specifications  of  applicable
product  safety  standards.  We  are  in  discussions  with  our  contract  manufacturer  of  the  MapcatSF  to  engage  an  NRTL  at  the  appropriate  juncture  prior  to
commercialization of the MapcatSF. The relevant predicate device for the MapcatSF is the MPS II, the applicable Class I product code for the MapcatSF is
HJW and the applicable Code of Federal Regulation is 886.1050. The FDA does not require test documents to be submitted to the FDA for a Class I medical
device, but that the evidence of such testing be placed in a Design History file and be kept internally at the Company or manufacturer and readily available
should the FDA or other regulatory bodies request to review the testing documents. While the FDA does not require that a Class I medical device have formal
validation, we expect to complete applicable IEC 60601-1 testing prior to commercialization as we believe in marketing a product that has evidence that it is
safe and effective.

Results of Operations

Through December 31, 2016, we had limited operations and have primarily been engaged in research and development and raising capital. We have incurred
significant expenditures for the development of the Company's products and intellectual property, which includes research and development of both medical
foods and medical diagnostic equipment for the treatment of various eye diseases. We had limited revenue during the years ended December 31, 2016 and
2015, all of which was generated by the sale of the Company’s proprietary product, Lumega-Z. In late 2014, the Company changed its focus from the dietary
supplement category to the medical food category based on consultation with the Company’s intellectual property counsel and regulatory affairs consultants,
as  a  result  of  which  Lumega-Z  was  categorized  and  sold  as  a  medical  food  in  2015  and  2016.  The  financial  impact  of  this  transition  to  the  medical  food
category in 2015 and 2016 is discussed below at sales and cost of goods sold. There were no other material impacts to revenue or expenses in 2015 or 2016
that resulted from the shift of Lumega-Z from the dietary supplement category to the medical food category.

Comparison of Years Ended December 31, 2016 and 2015

Revenue
Cost of goods sold
Gross Profit

Operating Expenses:
Research and development
Sales and marketing
General and administrative
Loss on settlement of promissory notes and accounts payable

Total Operating Expenses
Loss from Operations

Other Expense:
Interest expense
Cost to induce conversion of notes payable

Net Loss

Revenue

Year Ended December 31,

2016

2015

  $

141,029    $
75,702     
65,327     

112,811    $
50,072     
62,739     

Change

28,218     
25,630     
2,588     

64,026     
389,111     
3,308,144     
249,739     
4,011,020     
(3,945,693)    

401,909     
180,133     
5,610,830     
258,606     
6,451,478     
(6,388,739)    

(337,883)    
208,978     
(2,302,686)    
(8,867)    
(2,440,458)    
2,443,046     

1,802,704     
-     
(5,748,397)   $

752,948     
1,699,609     
(8,841,296)   $

1,049,756     
(1,699,609)    
3,092,899     

  $

25%
51%
4%

(84)%
116%
(41)%
(3)%
(38)%
(38)%

139%
(100)%
(35)%

For the year ended December 31, 2016, revenue from the sale of Lumega-Z was $141,029 compared to $112,811 for the year ended December 31, 2015,
reflecting an increase of $28,218 or 25%. The increase is reflective of an increased customer base as we expand into new clinics.

38

 
 
 
 
 
 
 
 
   
 
 
 
 
   
   
 
   
   
   
      
      
      
  
   
   
   
   
   
   
   
      
      
      
  
   
   
 
 
 
 
 
Cost of Goods Sold

For the year ended December 31, 2016, cost of goods sold from the sale of Lumega-Z was $75,702 compared to $50,072 for the year ended December 31,
2015, reflecting an increase of $25,630 or 51%. We incurred certain inventory adjustments of approximately $11,000 related to the disposal of packaging
materials that were determined to be obsolete during 2016 and approximately $(9,000) related to the transition from the dietary supplement category to the
medical foods category in 2015. These inventory adjustments were identified and recorded in 2016 and 2015 based on decisions made by management in
response to business developments occurring during the respective periods. As a result of these adjustments, cost of goods sold was 54% of revenue for the
year ended December 31, 2016 compared to 44% of revenue for the year ended December 31, 2015.

Research and Development

For the year ended December 31, 2016, research and development costs were $64,026 compared to $401,909 for the year ended December 31, 2015. The
decrease in research and development costs of $337,883 or 84% compared to the prior year was due primarily to stock-based compensation expense in 2015
of $342,000 for shares of common stock issued to a Science Advisor to the Company for services rendered.

Sales and Marketing

For  the  year  ended  December  31,  2016,  sales  and  marketing  expenses  were  $389,111  compared  to  $180,133  for  the  year  ended  December  31,  2015.  The
increase in sales and marketing expenses of $208,978 or 116% compared to the prior year was due primarily to the engagement of a Vice President of Sales
and Marketing in 2016.

General and Administrative

For the year ended December 31, 2016, general and administrative expenses were $3,308,144 compared to $5,610,830 for the year ended December 31, 2015.
The decrease in general and administrative expenses of $2,302,686 or 41% compared to the prior year was primarily due to the fair value of stock issued to
consultants  and  service  providers  during  2015  of  $4,419,959.  During  2016,  we  recognized  $1,811,990  in  comparable  stock  compensation  expense.  This
decrease was partially offset by an increase of $229,941 for legal and professional fees incurred primarily related to our SEC registration activities.

Loss on Settlement of Promissory Notes and Accounts Payable

In  December  2016,  the  Company  issued  534,154  shares  of  preferred  stock  valued  at  $784,888  upon  the  voluntary  conversion  of  $535,149  of  outstanding
principal and interest. The Company recognized a loss on settlement of the promissory notes of $249,739.

In  August  2015,  the  Company  issued  441,358  shares  of  common  stock  valued  at  $503,149  upon  the  conversion  of  $260,900  of  outstanding  principal  and
interest. The Company recognized a loss on settlement of the promissory notes of $242,249.

In  August  2015,  the  Company  issued  warrants  to  purchase  28,176  shares  of  common  stock  at  an  exercise  price  of  $0.01  per  share  and  a  3-year  term  in
settlement of $15,497 of accounts payable. The warrants were valued at $31,853, based upon the Black-Scholes option pricing model with a stock price of
$1.14, volatility of 105% and a risk-free rate of 1.09%. The Company recognized a loss on settlement of accounts payable of $16,357.

Interest Expense

For  the  year  ended  December  31,  2016,  interest  expense  was  $1,802,704  compared  to  $752,948  for  the  year  ended  December  31,  2015.  The  increase  in
interest expense of $1,049,756 or 139% compared to the prior year was due to an increase in non-cash interest expense resulting from the amortization of debt
discount related to the beneficial conversion features and warrants issued with our convertible notes as well as from the valuation of post-maturity warrants
issued in 2016.

39

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Cost to induce conversion of notes payable

Costs  to  induce  conversion  of  our  notes  payable  was  $1,699,609  for  the  year  ended  December  31,  2015.  There  was  no  such  comparable  cost  in  2016.  In
connection with the May 1, 2015 conversion of notes payable, we issued 995,926 membership units valued at $1,135,356 or $1.14 per share to the holders of
the notes as an inducement to convert their notes payable. In addition, we offered certain holders 146,000 warrants valued at $165,072 to acquire membership
units. The fair value of the warrants was based on a Black-Scholes option pricing model with a stock price of $1.14, volatility of 113% and risk-free rate of
0.97%. In connection with the May 1, 2015 conversion of related party notes payable, we issued 350,001 warrants valued at $341,785 to certain holders to
acquire membership units as inducement to convert the notes. The fair value of the warrants was based on a Black-Scholes option pricing model with a stock
price  of  $1.14,  volatility  of  113%  and  risk-free  rate  of  0.97%.  In  connection  with  the  August  10,  2015  conversion  of  notes  payable,  the  Company  issued
50,348 shares of its common stock valued at $57,396 to the holders of the notes as an inducement to convert their notes payable.

Net Loss

For the year ended December 31, 2016, the Company incurred a net loss of $5,748,397, compared to a net loss of $8,841,296 for the year ended December
31, 2015. The decrease in net loss of $3,092,899 or 35% compared to the prior year period was primarily due to the stock issued to consultants and service
providers  during  2015,  resulting  in  stock  compensation  expense  of  $4,885,589  (versus  $1,962,311  during  2016),  and  inducement  expense  of  $1,699,609
recognized in 2015 to convert notes payable. These year over year decreases were partially offset by the $1,049,756 increase in interest expense.

Liquidity and Capital Resources

Since our formation in 2009, we have devoted substantial effort and capital resources to the development and commercialization activities related to our lead
product  Lumega-Z  and  our  MapcatSF  medical  device.  As  a  result  of  our  activities  we  utilized  cash  in  operating  activities  of  $1,653,574  and  $1,139,758
during the years ended December 31, 2016 and 2015, respectively. We had negative working capital of $470,064 and $892,240 at December 31, 2016 and
2015, respectively. As of December 31, 2016, we had cash in the amount of $62,520 and no available borrowings. During the year ended December 31, 2016,
we converted $1,222,518 in outstanding principal and interest on our convertible notes and promissory notes into 1,651,732 shares of our common stock and
535,154 shares of our preferred stock. Our financing has historically come from the issuance of convertible notes and promissory notes and to a lesser extent
from the sale of common and preferred stock and exercise of warrants.

The financial statements have been prepared assuming the Company will continue as a going concern. The Company expects to continue to incur net losses
and negative operating cash flows in the near-term. As a result, management has concluded that there is substantial doubt about the Company’s ability to
continue as a going concern within one year of the date that the consolidated financial statements are issued.

The Company’s auditors have also included explanatory language in their opinion that there is substantial doubt about the Company’s ability to continue as a
going concern. The financial statements do not include any adjustments to reflect the possible future effects on the recoverability and classification of assets
or the amounts and classifications of liabilities that may result from the possible inability of the Company to continue as a going concern.

The Company will continue to incur significant expenses for commercialization activities related to its lead product Lumega-Z, the MapcatSF medical device,
and  with  respect  to  efforts  to  build  the  Company’s  infrastructure.  Development  and  commercialization  of  medical  foods  and  medical  devices  involves  a
lengthy  and  complex  process.  Additionally,  the  Company’s  long-term  viability  and  growth  will  depend  upon  the  successful  development  and
commercialization of products other than Lumega-Z and the MapcatSF. The Company is continuing attempts to raise additional debt and/or equity capital to
fund future operations, but there can be no assurances that the Company will be able to secure such additional financing in the amounts necessary to fully
fund its operating requirements on acceptable terms or at all. If the Company is unable to access sufficient capital resources on a timely basis, the Company
may be forced to reduce or discontinue its technology and product development programs and ultimately curtail or cease operations.

40

 
 
 
 
 
 
 
 
 
 
 
 
 
Sources and Uses of Cash

The following table sets forth our major sources and uses of cash for each of the following periods:

Net cash used in operating activities
Net cash used in investing activities
Net cash provided by financing activities
Net increase (decrease) in cash

Operating Activities

  Year Ended December 31,

2016
(1,653,574)   $
(3,354)    
1,705,598     
48,670    $

2015
(1,139,758)
(2,162)
1,149,610 
7,690 

  $

  $

Net cash used in operating activities was $1,653,574 during the year ended December 31, 2016, versus $1,139,758 used during the year ended December 31,
2015. The increase in 2016 was due primarily to additional general and administrative costs incurred in 2016 for consulting and other professional services
related to the filing with the SEC of our registration statement on Form S-1.

Investing Activities

Net cash used in investing activities was $3,354 for the year ended December 31, 2016 and $2,162 for the year ended December 31, 2015, and consisted of
investments in property and equipment for both years.

Financing Activities

Net cash provided by financing activities was $1,705,598 for the year ended December 31, 2016. Financing activities for the 2016 period provided proceeds
of $136,000 from the issuance of convertible notes payable, $360,000 in short-term loans partially offset by payments on those loans of $151,000, $1,145,000
in proceeds from the issuance of preferred stock, and $215,598 in amounts due to related parties on a net basis.

Net cash provided by financing activities was $1,149,610 the year ended December 31, 2015. Financing activities for 2015 provided proceeds of $542,500
from  the  issuance  of  convertible  notes  payable,  $300,000  from  the  issuance  of  promissory  notes,  $75,000  from  the  exercise  of  warrants,  and  $232,110  in
amounts due to related parties on a net basis.

Principal Commitments

The following table sets forth the Company’s principal cash obligations and commitments for the next five fiscal years as of December 31, 2016:

Convertible notes payable, currently due
Promissory notes payable, currently due
Operating lease commitments
Total

Total

2017

  $

  $

44,323    $
27,056     
194,309     
265,688    $

44,323    $
27,056     
121,599     
192,978    $

Payments Due by Year
2019

2018

2020

2021

—    $
—     
72,710     
72,710    $

—    $
—     
—     
—    $

—    $
—     
—     
—    $

— 
— 
— 
— 

41

 
 
 
 
 
 
 
 
   
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
   
   
   
   
   
 
   
   
 
 
 
Off-Balance Sheet Arrangements

At  December  31,  2016  and  2015,  the  Company  did  not  have  any  transactions,  obligations  or  relationships  that  could  be  considered  off-balance  sheet
arrangements.

ITEM 7A. QUANTITATIVE AND QUALITATIVE DISCLOSURE ABOUT MARKET RISK

Not applicable.

ITEM 8. FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

The Company’s consolidated financial statements and notes thereto and the related report of its independent registered public accounting firm follow Part IV,
Item 16 beginning on page F-1.

ITEM 9. CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL DISCLOSURE

Not applicable.

ITEM 9A. CONTROLS AND PROCEDURES

(a)            Disclosure Controls and Procedures. Under the supervision and with the participation of our senior management, consisting of our Chief Executive
Officer and Chief Accounting Officer, we conducted an evaluation of the effectiveness of the design and operation of our disclosure controls and procedures
(as  defined  in  Rules  13a-15(e)  and  15d-15(e)  under  the  Securities  Exchange  Act  of  1934,  as  amended  (the  "Exchange  Act"),  as  of  the  end  of  the  period
covered by this report (the "Evaluation Date"). Based on that evaluation, the Company's management concluded that as of the Evaluation Date our disclosure
controls and procedures were effective to ensure that information required to be disclosed by us in the reports that we file under the Exchange Act is recorded,
processed,  summarized  and  reported  within  the  time  periods  specified  in  SEC  rules  and  forms.  Our  disclosure  controls  and  procedures  include,  without
limitation,  controls  and  procedures  designed  to  ensure  that  information  required  to  be  disclosed  by  us  in  our  Exchange  Act  reports  is  accumulated  and
communicated to our management, including our chief executive officer and directors, as appropriate to allow timely decisions regarding required disclosure.

Management's Annual Report on Internal Control Over Financial Reporting. The Company's management is responsible for establishing and maintaining an
adequate system of internal control over financial reporting (as defined in Exchange Act Rule 13a-15(f)). Our internal control over financial reporting is a
process,  under  the  supervision  of  our  Chief  Executive  Officer  and  Chief  Accounting  Officer,  designed  to  provide  reasonable  assurance  regarding  the
reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles
in the United States. These internal controls over financial reporting processes include policies and procedures that:

a.            Pertain to the maintenance of records that in reasonable detail accurately and fairly reflect the transactions and dispositions of the assets of the
Company;

b.            Provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with generally
accepted accounting principles, and that receipts and expenditures of the Company are being made only in accordance with authorizations of management and
directors of the Company; and

c.            Provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use or disposition of the Company's assets that
could have a material effect on the financial statements.

Because  of  its  inherent  limitations,  internal  control  over  financial  reporting  may  not  prevent  or  detect  misstatements.  Therefore,  even  those  systems
determined to be effective can provide only reasonable assurance of achieving their control objectives.

42

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
In evaluating the effectiveness of our internal control over financial reporting, our management used the criteria set forth by the Committee of Sponsoring
Organizations of the Treadway Commission (COSO) in Internal Control - Integrated Framework 2013. Based on this evaluation, our Chief Executive Officer
and our Chief Accounting Officer concluded that our internal control over financial reporting was effective as of December 31, 2016.

This annual report does not include an attestation report of our registered public accounting firm regarding internal control over financial reporting.

Management's report was not subject to attestation by our registered public accounting firm pursuant to the rules of the Securities and Exchange Commission
that permit the Company to provide only management's report in this annual report.

(b)                        Changes  in  Internal  Control  over  Financial  Reporting.  There  were  no  changes  in  our  internal  control  over  financial  reporting  identified  in
connection with the evaluation required by paragraph (d) of Rule 13a-15 or Rule 15d-15 under the Exchange Act that occurred during or subsequent to the
Company's  last  fiscal  quarter  of  the  period  covered  by  this  report  that  have  materially  affected,  or  are  reasonably  likely  to  materially  affect,  our  internal
control over financial reporting.

ITEM 9B. OTHER INFORMATION

Not Applicable.

43

 
 
 
 
 
 
 
 
 
 
ITEM 10. DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE

PART III

Set forth below is certain information regarding our executive officers and directors. Each of the directors listed below was elected to our Board of Directors
to serve until our next annual meeting of stockholders or until his or her successor is elected and qualified. All directors hold office for one-year terms until
the  election  and  qualification  of  their  successors.  The  following  table  sets  forth  information  regarding  the  members  of  our  Board  of  Directors  and  our
executive officers:

Name

Age

Position

Michael Favish

Robert Weingarten

Mark Goldstone

Gordon Bethwaite

John Townsend

Vincent J. Roth

Management Team

68

64

53

40

55

49

  President, Chief Executive Officer and Chairman of the Board of Directors

  Director

  Director

  Vice President of Sales and Marketing

  Controller, Chief Accounting Officer

  General Counsel and Corporate Secretary

Michael Favish has been Chief Executive Officer, President and Chairman of the Board since the Company’s formation in 2009. He has more than 30 years’
experience in founding, developing and managing private and public companies, all of which we believe contribute to his qualifications as a director. He is an
acknowledged  and  respected  leader  and  innovator  with  hands-on  experience  in  strategic  marketing,  brand  building  and  product  development.  Mr.  Favish
founded  Fotoball  USA,  Inc.  (“Fotoball”),  a  pioneer  in  retail  licensed  products  and  marketing,  in  1984.  In  1994,  Mr.  Favish  transformed  Fotoball  into  a
publicly held company with 200 employees and was listed on the Nasdaq Stock Market. After growing revenues from $7 million in 1994 to $50 million in
2003,  Fotoball  was  acquired  in  January  2004  by  an  industry  leading  NYSE  company.  We  believe  that  Mr.  Favish’s  experience  in  an  entrepreneurial
environment such as Fotoball is particularly suitable for the Company because it was a small, developing and entrepreneurial company introducing products
of a kind that did not currently exist. Mr. Favish’s team building skills from his track record at Fotoball, are also applicable as the Company is still building its
departments  and  leadership  team.  Mr.  Favish  developed  familiarity  with  the  capital  markets  and  obligations  of  a  public  reporting  company  through  his
experience at Fotoball which is also pertinent to the Company as it engages in fund raising efforts and pursues its endeavor to become a public reporting
company. These experiences collectively make Mr. Favish suitable to serve the Company as Chief Executive Officer and a director.

Robert N. Weingarten has been a Director of the Company effective June 30, 2015. He is an experienced business consultant and advisor with an ongoing
consulting practice. Since 1979, he has provided financial consulting and advisory services and served on boards of directors of numerous public companies
in  various  stages  of  development,  operation  or  reorganization,  which  we  believe  qualifies  him  to  serve  on  our  Board  of  Directors.  Mr.  Weingarten  was
appointed  as  a  director  of  Staffing  360,  Inc.  on  February  25,  2014  and  resigned  this  position  on  April  20,  2014.  Mr.  Weingarten  was  the  Non-Executive
Chairman of New Dawn Mining Corp. (“New Dawn”) from August 31, 2005 through September 30, 2010, and was named the Executive Chairman of New
Dawn  in  October  2010.  On  July  8,  2010,  Mr.  Weingarten  was  appointed  to  the  Board  of  Directors  of  Central  African  Gold  Limited  (formerly  known  as
Central African Gold Plc and listed on the Alternative Investment Market of the London Stock Exchange at that time). Central African Gold Limited was an
indirect,  wholly-owned  subsidiary  of  New  Dawn.  Both  New  Dawn  and  Central  African  Gold  Limited  have  ceased  to  be  publicly  traded  and  reporting
companies in their respective jurisdictions. On April 29, 2013, Mr. Weingarten was appointed to the Board of Directors of RespireRx Pharmaceuticals Inc.,
formerly known as Cortex Pharmaceuticals, Inc. (“RespireRx”), and was named Vice President and Chief Financial Officer of RespireRx. He resigned from
those  positions  on  February  17,  2017.  Mr.  Weingarten  received  a  B.A.  Degree  in  Accounting  from  the  University  of  Washington  in  1974,  and  an  M.B.A.
Degree in Finance from the University of Southern California in 1975. Mr. Weingarten is a Certified Public Accountant (inactive) in the State of California.
Mr.  Weingarten  has  considerable  accounting  and  finance  acumen,  particularly  with  regard  to  public  reporting  requirements.  He  also  has  considerable
experience in the pharmaceutical industry, which has many similar regulatory requirements supplement as the medical foods and medical device markets in
which  the  Company  operates.  These  skills  and  experiences  make  Mr.  Weingarten  particularly  suitable  to  serve  as  a  director  and  offer  guidance  to  the
Company.

44

 
 
 
 
 
 
 
 
   
   
 
 
   
   
 
 
   
   
 
 
   
   
 
 
 
 
   
 
 
   
   
 
 
 
 
 
 
 
Mark Goldstone has been a Director since June 2015. Mr. Goldstone has over 25 years of experience in the healthcare industry, encompassing operations,
commercialization and consulting. He has executed numerous M&A, financing and strategic partnership transactions, for a broad array of middle market and
emerging growth companies in technology, life sciences and healthcare services, which qualifies him to serve on our Board of Directors. Mr. Goldstone was
the global President of DDB Worldwide Communications Group Inc.’s healthcare business, where he was responsible for a global communications business
spanning 40+ offices in over 36 markets. The business covered advertising, digital, integrated communications, healthcare professional promotion, branding,
naming, design, market shaping, medical education and scientific communications. Mr. Goldstone has previously held senior positions at Publicis Healthcare
Communications  Group  where  he  was  responsible  for  the  global  Sanofi-Aventis  business  and  at  Interbrand  where  he  was  CEO  of  its  global  Healthcare
business.

Mr. Goldstone moved from the United Kingdom to New York with Havas Group, where he held senior positions at Robert A. Becker, Euro RSCG and Jordan
McGrath  Case  &  Partners,  Euro  RSCG  and  ultimately  at  Euro  RSCG  Worldwide  Headquarters,  where  he  helped  devise  and  build  their  global  healthcare
business – Euro RSCG Life Worldwide (Now Havas Life). Mr. Goldstone holds a BSc (Hons) in Pharmacy. He is a board member of the prestigious Galien
Foundation and a board member of G3 Global Genomics Group. He is a member of the Royal Pharmaceutical Society of Great Britain and is a past Co-
Chairman  of  New  York  Corporate  Development  for  the  American  Diabetes  Association.  Mr.  Goldstone’s  breadth  of  experience  in  sales,  marketing  and
strategic  transactions  in  the  healthcare  industry  is  particularly  useful  to  the  Company  as  it  develops  its  business,  commercializes  products  and  builds  its
marketing  channels.  We  believe  that  these  experiences  make  Mr.  Goldstone  particularly  suitable  to  serve  as  a  director  and  guide  the  Company  in  the
complexities of the life science and healthcare services industries.

Gordon Bethwaite has been Vice President of Sales and Marketing since December 2015. He is a senior figure in the ophthalmic space, with over 15 years
of experience in the sales and marketing of diagnostic, surgical and optical products. After graduating with a degree in Applied Biology from Liverpool John
Moores University, Gordon transitioned into the corporate healthcare environment. Throughout his career, Gordon has held senior management positions in
both  the  ophthalmology  &  optometry,  and  audiology  industries.  From  October  2012  to  December  2015,  he  served  as  Market  Development  Manager  and
subsequently, Director of Marketing for the ophthalmic diagnostic and surgical portfolio at Carl Zeiss Meditec, a global leader and innovator in the industry.

Through his collaborations with thought leading doctors in cataract, refractive, retina and glaucoma specialties, Mr. Bethwaite brings a wealth of expertise
and knowledge to the table. A passion for the technological, clinical and surgical application, and business environment of the industry, coupled with an in-
depth understanding of the dynamics of the eye care market and years of collaboration with his customers, all combine to provide Mr. Bethwaite with a rich
skill set invaluable to his role as Vice President of Sales and Marketing for the Company.

John  Townsend  has  served  as  Controller  since  July  2016.  He  has  over  20  years  of  public  and  private  company  experience  in  industries  including
biotechnology, medical devices, and high-tech electronics manufacturing. Before joining the Company, Mr. Townsend worked at Cosmederm Biosciences,
Inc., a specialty pharmaceutical company. From 2005 until 2015, he worked at Cytori Therapeutics, Inc., a stem cell therapy company. From 1996 to 2005, he
worked at several high-tech companies, and he started his career at Deloitte (formerly Deloitte and Touche) after graduating from San Diego State University
in 1993. Mr. Townsend is a Certified Public Accountant in the state of California.

45

 
 
 
 
 
 
 
 
 
Vincent J. Roth has served as General Counsel and Corporate Secretary since April 2015. He is an experienced corporate attorney with over 16 years of
experience  serving  as  the  General  Counsel  to  public  and  private  companies  in  the  high-tech,  healthcare,  medical  device,  nutraceutical,  and  biotechnology
industries. Mr. Roth has worked as the General Counsel and Corporate Secretary for NucleusHealth, LLC (formerly StatRad, LLC), a medical device and
teleradiology company for the last seven years. Mr. Roth has also worked as a partner at InnovaCounsel, LLP providing general counsel services to clients for
the last eight years. In addition to managing legal affairs, Mr. Roth is very familiar with operating in highly regulated industries. Mr. Roth recently completed
a Master of Laws in Intellectual Property at the University of San Diego where he graduated with honors. He also received a Master of Laws in Business and
Corporate Law from the University of San Diego with honors, a Juris Doctor and an MBA from Temple University, a Master of Liberal Arts in Sociology
from the University of Pennsylvania and a BBA in Marketing and Human Resources from Temple University.

Director or Officer Involvement in Certain Legal Proceedings

Our directors and executive officers were not involved in any legal proceedings described in Item 401(f) of Regulation S-K in the past ten years.

Committees of the Board of Directors

Currently, our Board of Directors acts as our audit, nominating, corporate governance and compensation committees.   The Board of Directors has not yet
adopted charters relative to its audit committee, compensation committee and nominating committee.  Until such time as we add more members to the Board,
the entire Board will determine all matters and no committees have been formed. We intend to appoint persons to the Board of Directors and committees of
the Board of Directors as required to meet the corporate governance requirements of a national securities exchange, although we are not required to comply
with these requirements until we are listed on a national securities exchange. We intend to appoint directors in the future so that we have a majority of our
directors who will be independent directors, and of which at least one director will qualify as an “audit committee financial expert,” prior to a listing on a
national securities exchange.

ITEM 11. EXECUTIVE COMPENSATION

The  table  below  sets  forth,  for  the  last  two  fiscal  years,  the  compensation  earned  by  (i)  each  individual  who  served  as  our  principal  executive  officer  or
principal financial officer, and (ii) our most highly compensated executive officers, other than those listed in clause (i) above, who were serving as executive
officers  at  the  end  of  the  last  fiscal  year  (together,  the  “Named  Executive  Officers”).  No  other  executive  officer  had  annual  compensation  in  excess  of
$100,000 during the last fiscal year.

Executive

Michael Favish (1)

Vincent J. Roth (2)

Gordon Bethwaite (3)

John Townsend (4)

Year
2016
2015
2016
2015
2016
2015
2016
2015

  $
  $
  $
  $
  $
  $
  $
  $

Salary

Bonus

250,000    $
200,000    $
156,000    $
104,000    $
208,800    $
-    $
68,000    $
-    $

    Stock Awards    
-    $
-    $
-    $
-    $
-    $
-    $
-    $
-    $

4,500    $
-    $
10,350    $
1,500    $
1,800    $
2,500    $
450    $
-    $

All Other

Compensation    

Total

-    $
-    $
-    $
-    $
-    $
-    $
-    $
-    $

254,500 
200,000 
166,350 
105,500 
210,600 
2,500 
68,450 
- 

(1) Michael Favish has been the Company’s CEO since inception. He does not have a written agreement with the Company. Mr. Favish received 5,500,000
units of membership interest at inception of the Company on December 1, 2009 when the Company was a California limited liability company, such units
became 5,500,000 shares of common stock when the Company incorporated as a Delaware corporation on June 30, 2015. The Company accrued a salary of
$200,000  for  Mr.  Favish  in  fiscal  year  2015  and  $250,000  in  fiscal  year  2016.  Mr.  Favish  was  awarded  a  stock  grant  on  December  31,  2016  for  services
rendered  for  50,000  shares  of  the  Company’s  common  stock  valued  at  $0.09  per  share.  It  is  expected  that  Mr.  Favish  will  be  engaged  with  a  formal
employment agreement in 2017.

(2) Vincent J. Roth began as the Company’s General Counsel and Corporate Secretary on May 6, 2015 with annual compensation of $156,000. Mr. Roth was
awarded a stock grant on August 7, 2015 for services rendered for 150,000 shares of the Company’s common stock valued at $0.01 per share. Mr. Roth was
awarded stock grants on April 1, 2016 and December 31, 2016, for services rendered for 100,000 and 15,000 shares, respectively, of the Company’s common
stock valued at $0.09 per share. It is expected that Mr. Roth will be engaged with a formal employment agreement in 2017.

46

 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(3) Gordon Bethwaite was awarded a stock grant on October 1, 2015 for 250,000 shares of the Company’s common stock valued at $0.01 per share as an
inducement to engage as the Company’s Vice President of Sales and Marketing and to compensate Mr. Bethwaite for work to be performed. These shares
reverse vest quarterly over the first year, with the first quarter vested on January 1, 2016. Mr. Bethwaite officially began his engagement as Vice President of
Sales and Marketing on January 1, 2016 with an annualized compensation of $208,800. Mr. Favish was awarded a stock grant on December 31, 2016 for
services  rendered  for  20,000  shares  of  the  Company’s  common  stock  valued  at  $0.09  per  share.  It  is  expected  that  Mr.  Bethwaite  will  be  engaged  with  a
formal employment agreement in 2017.

(4) John Townsend began as the Company’s Controller July 1, 2016 with annual compensation of $144,000. Mr. Townsend was awarded a stock grant on
December 31, 2016 for services rendered for 5,000 shares of the Company’s common stock valued at $0.09 per share. It is expected that Mr. Townsend will
be engaged with a formal employment agreement in 2017.

Outstanding Equity Awards at Fiscal Year-End

Other  than  as  set  forth  below,  there  were  no  outstanding  unexercised  options,  unvested  stock,  and/or  equity  incentive  plan  awards  issued  to  our  named
executive officers as of December 31, 2016.

Option Award

Stock Award

Equity
Incentive
Plan
Awards:
Number
of
Unearned
Shares,
Units or
Other
Rights
That
Have Not
Vested
(#)

Equity
Incentive
Plan
Awards:
Market
or Payout
Value of
Unearned
Shares,
Units or
Other
Rights
That
Have Not
Vested
($)

Number of
Securities
Underlying
Unexercised
Warrants/
Options
Exercisable  

Number of
Securities
Underlying
Unexercised
Warrants/
Options
Unexercisable 

Equity
Incentive
Plan
Awards:
Number of
Securities
Underlying
Unexercised
Unearned
Warrants  

Warrant
Exercise
Price
($)

Warrant
Expiration
Date

Number
of
Shares
or Units
of Stock
That
Have
Not
Vested
(#)
100,000(a)  
250,000(b) 

Market
Value
of
Shares
or Units
of Stock
That
Have Not
Vested
($)

Name
Vincent Roth
Gordon Bethwaite

(a) These shares were 75% vested as of December 31, 2016. The remaining 25% vested in January 2017.
(b) These shares were 75% vested as of December 31, 2016. The remaining 25% vest in June 2017.

Director Compensation

The Company awarded stock grants to its directors as compensation for serving in such capacity, as show in the table below.

Director (1)

Mark Goldstone

Robert Weingarten

Year
2016
2015
2016
2015

  Stock Awards 
4,500 
  $
- 
  $
4,500 
  $
- 
  $

47

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
  
 
 
  
 
 
  
 
 
  
 
 
 
  
 
 
  
 
 
  
 
 
  
 
 
  
 
 
  
 
 
  
 
 
  
 
 
 
  
 
 
  
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(1) Mr. Goldstone and Mr. Weingarten have been Directors of the Company since June, 2015. Each Director was awarded a stock grant on December 31,
2016 for services rendered for 50,000 fully vested shares of the Company’s common stock valued at $0.09 per share.

ITEM  12.  SECURITY  OWNERSHIP  OF  CERTAIN  BENEFICIAL  OWNERS  AND  MANAGEMENT  AND  RELATED  STOCKHOLDER
MATTERS

The  following  table  sets  forth  certain  information  regarding  our  common  stock,  beneficially  owned  as  of  March  17,  2017  (i)  each  person  known  to  us  to
beneficially own more than 5% of our common stock, (ii) each executive officer and director, and (iii) all officers and directors as a group.  The following
table is based on the Company having 25,146,438 shares of common stock issued and outstanding as of March 17, 2017. We calculated beneficial ownership
according to Rule 13d-3 of the Securities Exchange Act of 1934, as amended as of that date.  Shares of our common stock issuable upon exercise of options
or warrants or conversion of notes that are exercisable or convertible within 60 days after March 17, 2017 are included as beneficially owned by the holder,
but not deemed outstanding for computing the percentage of any other stockholder for Percentage of Common Stock Beneficially Owned. For each individual
and group included in the table below, percentage ownership is calculated by dividing the number of shares beneficially owned by such person or group by
the sum of the 25,146,438 shares of common stock outstanding at March 17, 2017, plus the number of shares of common stock that such person or group had
the  right  to  acquire  on  or  within  60  days  after  March  17,  2017.  Beneficial  ownership  generally  includes  voting  and  dispositive  power  with  respect  to
securities.  Unless otherwise indicated below, the persons and entities named in the table have sole voting and sole dispositive power with respect to all shares
beneficially owned.

Name of Beneficial Owner and Title of Officers and Directors

Michael Favish, Chief Executive Officer, President and Director (a)
Robert N. Weingarten, Director
Mark Goldstone, Director (b)
Gordon Bethwaite, Vice President (c)
John Townsend, Controller (d)
Vincent J. Roth, General Counsel and Corporate Secretary (e)
All Officers and Directors as a Group (5 persons) (f)
5% Shareholders:
Christopher Scangas (g)
Leon Krajian (h)
Edward Grier (i)
Jeffrey Morris (j)

Shares of 
Common Stock 
Beneficially 
Owned

Percentage of 
Common 
Stock 
Beneficially 
Owned

6,494,933     
1,300,000     
1,050,000     
270,000     
5,000     
265,000     
9,384,933     

2,608,489     
3,674,789     
2,110,186     
1,278,211     

25.83%
5.17%
4.18%
1.07%
0.02%
1.05%
37.32%

10.36%
13.64%
8.16%
5.08%

Includes 260,000 shares held by Mr. Favish’s spouse.

(a)
(b) Includes 1,000,000 shares of restricted common stock of the Company that vest semiannually over twenty-one months. These shares are 75% vested

(c)

as of March 17, 2017.
Includes 250,000 shares of restricted common stock of the Company that vest semiannually over twenty-one months. These shares are 75% vested as
of March 17, 2017.

(d) Includes 5,000 shares of common stock.
(e)

Includes 100,000 shares of restricted common stock of the Company that vest quarterly over a one-year period. These shares are fully vested as of
March 17, 2017.

(f) Unless otherwise indicated, the business address of each individual is c/o Guardion Health Sciences, Inc., 15150 Avenue of Science, Suite 200, San

Diego, California 92128.

(g) Includes 2,075,753 shares held in the name of Cynthia Elaine Trust dated December 12, 2014; 138,750 shares held in the name of Cynthia Elaine
Scangas Dated June 12 2002-IRA rollover, BNY Mellon Trustee; 363,986 shares held in the name of Jason Scangas, the son of Christopher Scangas,
for  whom  Christopher  Scangas  holds  Power  of  Attorney;  and  30,000  shares  that  may  be  purchased  pursuant  to  an  exercisable  warrant  issued  to
Christopher Scangas that is vested and expires March 29, 2019.

48

 
 
 
 
 
 
   
 
 
 
 
   
 
 
   
   
   
   
   
   
   
   
      
  
   
   
   
   
 
 
 
 
(h) Includes 231,974 shares held in the name of Equity Trust Company Custodian FBO Leon S. Krajian IRA; 146,000 shares that may be purchased
pursuant to an exercisable warrant issued to Equity Trust Company Custodian FBO Leon S. Krajian IRA that is vested and expires May 1, 2018;
1,135,000 shares that may be purchased pursuant to exercisable warrants issued to Leon Krajian that are vested and expire at various dates between
September  30,  2018  and  December  31,  2019;  and  518,092  shares  of  common  stock  that  may  be  issued  upon  conversion  of  310,855  shares  of
preferred stock owned by Mr. Krajian.
Includes 327,500 shares that may be purchased pursuant to exercisable warrants issued to Edward Grier that are vested and expire at various dates
between November 30, 2018 and August 24, 2019; and 373,832 shares of common stock that may be issued upon conversion of 224,299 shares of
preferred stock owned by Mr. Grier.

(i)

(j) Shares are held in the name of Jeff and Phyllis Morris Family Trust UDT Dated June 11, 1999; includes an exercisable warrant to purchase 30,237

shares that is vested and expires May 1, 2018.

ITEM 13. CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS AND DIRECTOR INDEPENDENCE

Due to and from related parties represents unreimbursed expenses and compensation incurred on behalf of, and amounts loaned to the Company by, Michael
Favish, the Company’s Chief Executive Officer, as well as other shareholders. The advances are unsecured, non-interest bearing and are due on demand. As
of December 31, 2016 and 2015, the Company had $91,483 and $286,844, respectively, due to related parties.

The Company paid management fees directly to Michael Favish prior to the Company’s conversion to a corporation. During the first six months of 2015, the
Company  accrued  management  fees  of  $106,250  and  paid  $6,250.  During  the  remaining  six-month  period  ended  December  31,  2015  (subsequent  to
conversion  to  a  corporation  in  June  of  2015),  the  Company  accrued  salary  expense  of  $100,000  and  paid  $0.  During  the  twelve-month  period  ended
December 31, 2016, the Company accrued salary expense of $250,000 and paid $48,500. For all periods presented, accrued amounts are included in general
and administrative expenses.

On December 31, 2016, the Company issued 684,933 shares of common stock, converted at $0.60 per share, to our CEO, Michael Favish, in settlement of
$410,960 of previously accrued management and other fees earned by Mr. Favish from 2013 through 2016. The difference of $191,781 between the fair value
of the shares issued and accrued fees was reflected as additional compensation in general and administrative expenses.

On December 31, 2016, the Company awarded stock grants to its management and directors as compensation for services rendered. This included 50,000
shares each to Michael Favish, our CEO, Mark Goldstone, a Director, and Robert Weingarten, a Director. 20,000 shares were awarded to Gordon Bethwaite,
our Vice President of Sales and Marketing, 15,000 shares were awarded to Vincent J. Roth, our General Counsel and Corporate Secretary and 5,000 shares
were awarded to John Townsend, our Controller. All of these shares were fully vested on December 31, 2016. The Company recorded $162,800 of stock-
based compensation as a result of these awards.

As of December 31, 2016, $14,000 of principal and $2,085 of accrued interest was outstanding for a note held by Terrence Favish, son of our CEO, Michael
Favish. The note carries a 12% interest rate.

For  the  year  ended  December  31,  2015,  the  Company  recorded  $2,485,450  of  stock-based  compensation,  for  services  rendered,  to  individuals  that  were
related  parties  at  the  time  of  issuance.  This  included  $1,423,750  recorded  for  stock  issued  to  Robert  Weingarten,  a  director,  $477,714  recorded  for  stock
issued  to  Mark  Goldstone,  a  director,  $285,000  recorded  for  stock  issued  to  Karen  M.  Favish,  wife  of  CEO  Michael  Favish,  $119,419  recorded  for  stock
issued to Gordon Bethwaite, Vice President of Sales and Marketing, $171,000 recorded for stock issued to Vincent J. Roth, General Counsel and Corporate
Secretary, and $8,557 recorded for stock issued to Marie Powell, mother of Karen M. Favish whose investment was purchased on Ms. Powell’s behalf by
Mrs. Favish.

49

 
 
 
 
 
 
 
 
 
 
 
 
ITEM 14. PRINCIPAL ACCOUNTANT FEES AND SERVICES

Weinberg & Company, P.C. acted as the Company’s independent registered public accounting firm for the years ended December 31, 2016 and 2015 and for
the  interim  periods  in  such  fiscal  years.  The  following  table  shows  the  fees  that  were  incurred  by  the  Company  for  audit  and  other  services  provided  by
Weinberg & Company, P.C. for the years ended December 31, 2016 and 2015.

Audit Fees (a)
Tax Fees (b)
Other Fees (c)
Total

Year Ended December 31,

2016

2015

  $

  $

84,426    $
37,350     
19,073     
140,849    $

87,185 
- 
- 
87,185 

(a) Audit fees represent fees for professional services provided in connection with the audit of the Company’s annual financial statements and the review
of its financial statements included in the Company’s Quarterly Reports on Form 10-Q and services that are normally provided in connection with
statutory or regulatory filings.

(b) Tax fees represent fees for professional services related to tax compliance, tax advice and tax planning.
(c) Other fees represent fees related to our filing of a Registration Statement on Form S-1.

All audit related services, tax services and other services rendered by Weinberg & Company, P.C. were pre-approved by the Company’s Board of Directors.
The Board of Directors has adopted a pre-approval policy that provides for the pre-approval of all services performed for the Company by its independent
registered public accounting firm. Our  independent  registered  public  accounting  firm  and  management  are  required  to  periodically  report  to  the  Board  of
Directors regarding the extent of services provided by the independent registered public accounting firm in accordance with this pre-approval, and the fees for
the services performed to date.

50

 
 
 
 
 
 
 
 
 
   
 
   
   
 
 
 
 
 
ITEM 15. EXHIBITS AND FINANCIAL STATEMENT SCHEDULES

(a)

list of documents filed as part of this report:

(1)

Financial Statements

PART IV

Reference is made to the Index to Financial Statements on page F-1, where these documents are listed.

(2)

Financial Statement Schedules

The  financial  statement  schedules  have  been  omitted  because  the  required  information  is  not  applicable,  or  not  present  in  amounts  sufficient  to  require
submission of the schedules, or because the information is included in the financial statements or notes thereto.

(3)

Exhibits

(b)

Exhibits:

A list of exhibits required to be filed as part of this Annual Report on Form 10-K is set forth in the Index to Exhibits, which is presented elsewhere in this
document, and is incorporated herein by reference.

ITEM 16. FORM 10-K SUMMARY

None.

51

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Guardion Health Sciences, Inc.
Financial Statements and Footnotes
Contents

Report of Independent Registered Public Accounting Firm

Financial Statements

Balance Sheets – As of December 31, 2016 and 2015

Statements of Operations – For the Years Ended December 31, 2016 and 2015

Statements of Members’ and Stockholders’ Deficiency – For the Years Ended December 31, 2016 and 2015

Statements of Cash Flows – For the Years Ended December 31, 2016 and 2015

Notes to Financial Statements

F-1

F-2

F-3

F-4

F-5

F-6

F-7

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Board of Directors
Guardion Health Sciences, Inc.
San Diego, California

We have audited the accompanying balance sheets of Guardion Health Sciences, Inc. (the "Company") as of December 31, 2016 and 2015 and the related
statements of operations, members’ and stockholders' deficiency, and cash flows for the years then ended. These financial statements are the responsibility of
the Company's management. Our responsibility is to express an opinion on these financial statements based on our audits.

We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that
we plan and perform our audits to obtain reasonable assurance about whether the financial statements are free of material misstatement. The Company is not
required  to  have,  nor  were  we  engaged  to  perform,  an  audit  of  its  internal  control  over  financial  reporting.  Our  audits  included  consideration  of  internal
control  over  financial  reporting  as  a  basis  for  designing  audit  procedures  that  we  considered  appropriate  in  the  circumstances,  but  not  for  the  purpose  of
expressing an opinion on the effectiveness of the Company's internal control over financial reporting. Accordingly, we express no such opinion. An audit
includes  examining,  on  a  test  basis,  evidence  supporting  the  amounts  and  disclosures  in  the  financial  statements.  An  audit  also  includes  assessing  the
accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that
our audits provide a reasonable basis for our opinion.

In our opinion, the financial statements referred to above present fairly, in all material respects, the financial position of Guardion Health Sciences, Inc. as of
December 31, 2016 and 2015, and the results of its operations and its cash flows for the years then ended, in conformity with accounting principles generally
accepted in the United States of America.

The  accompanying  financial  statements  have  been  prepared  assuming  that  the  Company  will  continue  as  a  going  concern.  As  discussed  in  Note  1,  the
Company has experienced negative operating cash flows since inception and has a stockholders’ deficiency as of December 31, 2016. These matters raise
substantial doubt about the Company's ability to continue as a going concern. Management's plans in regard to these matters are also described in Note 1 to
the financial statements. These financial statements do not include any adjustments that might result from the outcome of this uncertainty.

/s/ Weinberg & Company, P.A.

Weinberg & Company, P.A.
Los Angeles, California
March 30, 2017

F-2

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Guardion Health Sciences, Inc.

Balance Sheets

December 31,

2016

2015

  $

62,520    $
1,673     
43,999     
29,363     

13,850 
1,136 
30,563 
18,950 

137,555     

64,499 

10,470     
114,020     

10,470 
170,795 

  $

262,045    $

245,764 

Assets

Current assets
Cash
Accounts receivable
Inventories
Current portion of deposits and prepaid expenses

Total current assets

Deposits and prepaid expenses, less current portion
Property and equipment, net

Total assets

Liabilities, and Members’ and Stockholders’ Deficiency

Current liabilities

Accounts payable and accrued liabilities
Accrued expenses and deferred lease costs
Due to related parties
Current portion of convertible notes payable
Current portion of promissory notes payable, net of debt discount of $0 and $36,018, respectively
Current portion of promissory notes payable related party, net of debt discount of $0 and $54,639, respectively

  $

Total current liabilities

Convertible notes payable

Total liabilities

Commitments and contingencies

Members’ and Stockholders’ Deficiency

Preferred stock, $0.001 par value; 10,000,000 shares authorized; 1,705,154 shares issued and outstanding at

December 31, 2016

Common stock, $0.001 par value; 90,000,000 shares authorized; 25,046,438 and 21,911,396 shares issued and

outstanding at December 31, 2016 and December 31, 2015

Additional paid-in capital
Accumulated deficit

Total members’ and stockholders’ deficiency

356,467    $
88,290     
91,483     
44,323     
10,251     
16,805     

271,863 
143,077 
286,844 
41,315 
64,407 
149,233 

607,619     

956,739 

-     

516,575 

607,619     

1,473,314 

1,705     

- 

25,046     
20,277,882     
(20,650,207)    

21,911 
12,857,320 
(14,106,781)

(345,574)    

(1,227,550)

Total liabilities, and members’ and stockholders’ deficiency

  $

262,045    $

245,764 

See accompanying notes to financial statements.

F-3

 
 
 
 
 
 
 
 
 
   
 
 
   
     
 
   
      
  
 
   
      
  
   
      
  
   
   
   
 
   
      
  
   
 
   
      
  
   
   
 
   
      
  
 
   
      
  
   
      
  
 
   
      
  
   
      
  
   
   
   
   
   
 
   
      
  
   
 
   
      
  
   
 
   
      
  
   
 
   
      
  
   
      
  
 
   
      
  
   
      
  
 
   
      
  
   
   
   
   
 
   
      
  
   
 
   
      
  
 
 
 
 
Guardion Health Sciences, Inc.

Statements of Operations

Revenue

Cost of goods sold

Gross profit

Operating expenses

Research and development
Sales and marketing
General and administrative
Loss on settlement of promissory notes and accounts payable

Total operating expenses

Loss from operations

Other expenses:

Interest expense and financing costs
Change in fair value of note
Cost to induce conversion of notes payable

Total other expenses

Net loss

Adjustments related to Series A 8% convertible preferred stock:

Accretion of deemed dividend
Dividend declared

Net loss attributable to common shareholders

Net loss per common share – basic and diluted
Weighted average common shares outstanding – basic and diluted

See accompanying notes to financial statements.

F-4

Years Ended December 31,

2016

2015

  $

141,029    $

112,811 

75,702     

50,072 

65,327     

62,739 

64,026     
389,111     
3,308,144     
249,739     

401,909 
180,133 
5,610,830 
258,606 

4,011,020     

6,451,478 

(3,945,693)    

(6,388,739)

1,104,557     
698,147     
-     

752,948 
- 
1,699,609 

1,802,704     

2,452,557 

(5,748,397)    

(8,841,296)

  $

  $

(760,011)    
(35,018)    
(6,543,426)   $

- 
- 
(8,841,296)

(0.30)   $
21,800,719     

(0.54)
16,391,665 

 
 
 
 
 
 
 
 
 
   
 
 
   
     
 
 
   
      
  
   
 
   
      
  
   
 
   
      
  
   
      
  
   
   
   
   
 
   
      
  
   
 
   
      
  
   
 
   
      
  
   
      
  
   
   
   
 
   
      
  
   
 
   
      
  
   
 
   
      
  
   
      
  
   
   
 
   
      
  
   
 
 
 
 
Guardion Health Sciences, Inc.

Statements of Members’ and Stockholders’ Deficiency

Members’ Capital

Preferred Stock

Common Stock

  Amount  
- 
  $

Shares

- 

- 

- 

- 

- 
- 

- 

- 

- 

- 

- 

- 
- 
- 

- 

- 

- 
- 
- 
- 

- 

Balance at December 31, 2014
Fair value of warrants issued with convertible

notes payable

Issuance of convertible notes payable -

beneficial conversion feature

Issuance of membership units – conversion of

notes payable and related interest

Issuance of membership units as inducement to

convert

Issuance of warrants as inducement to convert
Issuance of membership units for

consulting services

Issuance of membership units to related party

upon warrant exercise

Net loss – January 1, 2015 through June 30,

2015

Conversion of membership units to common

Units
    10,821,827 

  Amount
  $ 3,452,852 

Shares

- 

- 

16,656 

25,844 

2,659,294 

    1,429,035 

995,926 
- 

    1,135,356 
506,857 

2,303,227 

    2,625,679 

450,000 

90,000 

- 

- 

stock on June 30, 2015

    (17,230,274)     (9,282,279)    

Issuance of common stock – conversion of

notes payable, promissory notes payable and
related interest

Issuance of common stock as inducement to

convert

Issuance of common stock for services
Issuance of common stock – warrant exercises    
Fair value of warrants issued with notes

payable

Fair value of warrants issued in conversion of

accounts payable

Net loss – July 1, 2015 through December 31,

2015

Balance at December 31, 2015
Issuance of common stock for services
Fair value of warrants issued for services
Fair value of post-maturity warrants issued as

additional interest on notes payable

Issuance of common stock – conversion of

accrued management fees
Issuance of preferred stock
Fair value of preferred stock – conversion of

notes payable and related interest

Fair value of common stock – conversion of

notes payable and related interest

Fair value of warrants issued with convertible

notes payable

Issuance of convertible notes payable –

beneficial conversion feature

Accretion of beneficial conversion feature on

preferred stock

Dividend on preferred stock
Net loss
Balance at December 31, 2016

- 

- 
- 
- 

- 

- 

- 
- 
- 
- 

- 

- 
- 

- 

- 

- 

- 

- 
- 
- 
- 

  $

- 

- 
- 
- 

- 

- 

- 
- 
- 
- 

- 

- 
- 

- 

- 

- 

- 

- 
- 
- 
- 

- 
    1,170,000 

535,154 

- 

- 

- 

- 
1,170 

535 

- 

- 

- 

- 

- 

- 

- 
- 

- 

- 

- 

- 

- 

- 
- 
- 

- 

- 

- 
- 
- 
- 

- 

  Amount  
- 
  $

Additional
Paid-In
Capital

  $

- 

- 

- 

- 
- 

- 

- 

- 

- 

- 

- 

- 

- 
- 

- 

- 

- 

Total
Members’
and
Stockholders’
Deficiency  
  $ (5,265,485)   $ (1,812,633)

Accumulated
Deficit

- 

- 

- 

- 
- 

- 

- 

16,656 

25,844 

1,429,035 

1,135,356 
506,857 

2,625,679 

90,000 

(5,094,421)  

(5,094,421)

- 

- 

- 

- 

- 
- 

- 

- 

- 

  17,230,274 

17,230 

9,265,049 

1,328,346 

50,348 
2,719,091 
583,337 

- 

- 

1,290 

56 
2,752 
583 

- 

- 

982,699 

57,341 
2,261,052 
77,750 

181,576 

31,853 

- 
  21,911,396 
740,000 
- 

- 
21,911 
740 
- 

- 
  12,857,320 
1,424,944 
344,846 

- 

684,933 
- 

- 

- 

685 
- 

- 

575,673 

602,056 
1,168,830 

784,353 

1,651,732 

1,652 

1,383,864 

- 

- 

- 

- 

270,076 

70,949 

- 

- 

- 
- 
- 

- 

- 

(3,746,875)  
(14,106,781)  

- 
- 

- 

- 
- 

- 

- 

- 

- 

- 

983,989 

57,397 
2,263,804 
78,333 

181,576 

31,853 

(3,746,875)
(1,227,550)
1,425,684 
344,846 

575,673 

602,741 
1,170,000 

784,888 

1,385,516 

270,076 

70,949 

- 
- 
(5,748,397)
(345,574)

- 
- 
- 
    1,705,154 

  $

- 
- 
- 
1,705 

- 
58,377 
- 
  25,046,438 

  $

- 
58 
- 
25,046 

760,011 
34,960 
- 
  $ 20,277,882 

(760,011)  
(35,018)  
(5,748,397)  

  $ (20,650,207)   $

See accompanying notes to financial statements.

F-5

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
Guardion Health Sciences, Inc.

Statements of Cash Flows

Operating Activities

Net loss
Adjustments to reconcile net loss to net cash used in operating activities:

Depreciation and amortization
Amortization of debt discount
Change in fair value of note
Accrued interest expense included in notes payable
Fair value of warrants issued as post-maturity interest
Stock-based compensation
Stock-based compensation – related parties
Management fee compensation expense
Loss on settlement of promissory notes payable and accounts payable
Inducement expense on conversions of notes payable to equity
Warrants issued in payment of accounts payable

Changes in operating assets and liabilities:

(Increase) decrease in -
Accounts receivable
Inventories
Deposits and prepaid expenses
Increase (decrease) in -
Accounts payable and accrued expenses
Accrued and deferred rent costs

Net cash used in operating activities

Investing Activities

Purchase of property and equipment

Net cash used in investing activities

Financing Activities

Proceeds from issuance of convertible notes payable
Proceeds from issuance of promissory notes – related party
Proceeds from issuance of promissory notes
Payments on promissory notes
Proceeds from issuance of preferred stock
Proceeds from exercise of warrants
Increase in due to related parties

Net cash provided by financing activities

Cash:
Net increase (decrease)
Balance at beginning of period
Balance at end of period

Supplemental disclosure of cash flow information:

Cash paid for -
Interest
Income taxes

Non-cash financing activities:

Issuance of common stock upon conversion of accrued management fees
Issuance of preferred stock upon conversion of notes payable and related interest
Issuance of common stock upon conversion of notes payable and related interest
Fair value of warrants issued in connection with promissory and convertible notes payable
Beneficial conversion feature associated with promissory and convertible notes payable
Accrued interest on notes payable utilized to exercise warrants
Fair value of warrants issued in conversion of accounts payable

See accompanying notes to financial statements.

F-6

Years Ended December 31,

2016

2015

  $

(5,748,397)   $

(8,841,296)

60,129     
431,681     
698,147     
86,711     
575,673     
787,684     
982,846     
191,781     
249,739     
-     
-     

(537)    
(13,436)    
14,587     

84,605     
(54,787)    

53,741 
642,029 
- 
110,919 
- 
2,400,139 
2,485,450 
- 
258,606 
1,699,609 
7,993 

(97)
(6,335)
(9,345)

76,112 
(17,283)

(1,653,574)    

(1,139,758)

(3,354)    

(3,354)    

136,000     
140,000     
220,000     
(151,000)    
1,145,000     
-     
215,598     

(2,162)

(2,162)

542,500 
200,000 
100,000 
- 
- 
75,000 
232,110 

1,705,598     

1,149,610 

48,670     
13,850     
62,520    $

7,690 
6,160 
13,850 

-    $
-    $

- 
- 

410,960    $
535,149    $
687,369    $
270,075    $
70,949    $
-    $
-    $

- 
- 
2,412,809 
198,232 
25,844 
93,333 
7,504 

  $

  $
  $

  $
  $
  $
  $
  $
  $
  $

 
 
 
 
 
 
 
 
 
   
 
 
   
     
 
   
      
  
   
      
  
   
   
   
   
   
   
   
   
   
   
   
   
      
  
   
      
  
   
   
   
   
      
  
   
   
 
   
      
  
   
 
   
      
  
   
      
  
   
 
   
      
  
   
 
   
      
  
   
      
  
   
   
   
   
   
   
   
 
   
      
  
   
 
   
      
  
   
      
  
   
   
 
   
      
  
   
      
  
   
      
  
 
   
      
  
   
      
  
 
 
 
 
Guardion Health Sciences, Inc.
Notes to Financial Statements
Years Ended December 31, 2016 and 2015

1.

Organization and Business Operations

Organization and Business

Guardion  Health  Sciences,  Inc.  (the  “Company”)  was  formed  in  December  2009  as  a  California  limited  liability  company  under  the  name  P4L  Health
Sciences, LLC. On June 30, 2015, the Company converted from a California limited liability company to a Delaware corporation, changing its name from
Guardion Health Sciences, LLC to Guardion Health Sciences, Inc.

The Company is a specialty health sciences company formed to develop, formulate and distribute condition-specific medical foods with an initial medical
food product on the market under the brand name Lumega-Z® that replenishes and restores the macular protective pigment. A depleted macular protective
pigment  is  a  modifiable  risk  factor  for  retina  based  diseases  such  as  age-related  macular  degeneration  (“AMD”),  computer  vision  syndrome  (“CVS”)  and
diabetic  retinopathy.  Additional  research  has  also  shown  a  depleted  macular  protective  pigment  to  be  a  biomarker  for  neurodegenerative  diseases  such  as
Alzheimer’s and dementia. The Company has developed a proprietary, patented medical device called the MapcatSF® that accurately measures the macular
pigment optical density (“MPOD”).

Through December 31, 2016, the Company has had limited operations, but has been primarily engaged in research and development and capital raising. The
Company  has  incurred  significant  expenditures  for  the  development  of  the  Company's  products  and  intellectual  property,  which  includes  research  and
development of both medical foods and medical diagnostic equipment for the treatment of various eye diseases. The Company had limited revenue during the
years ended December 31, 2016 and 2015, all of which was generated by the sale of the Company’s proprietary product, Lumega-Z, during such periods. In
late  2014,  the  Company  changed  its  focus  from  the  dietary  supplement  category  to  the  medical  food  category  based  on  consultation  with  the  Company’s
intellectual property counsel and regulatory affairs consultants, as a result of which Lumega-Z was categorized and sold as a medical food in 2015 and 2016.

Going Concern and Liquidity

The financial statements have been prepared assuming the Company will continue as a going concern. The Company has utilized cash in operating activities
of  $1,653,574  and  $1,139,758  during  the  years  ended  December  31,  2016  and  2015,  respectively,  and  had  a  deficit  of  $345,574  and  $1,227,550  as  of
December 31, 2016 and 2015, respectively. The Company expects to continue to incur net losses and negative operating cash flows in the near-term. As a
result, management has concluded that there is substantial doubt about the Company’s ability to continue as a going concern within one year of the date that
the consolidated financial statements are issued.

The Company’s auditors have also included explanatory language in their opinion that there is substantial doubt about the Company’s ability to continue as a
going concern. The financial statements do not include any adjustments to reflect the possible future effects on the recoverability and classification of assets
or the amounts and classifications of liabilities that may result from the possible inability of the Company to continue as a going concern.

The Company will continue to incur significant expenses for commercialization activities related to its lead product Lumega-Z, the MapcatSF medical device,
and  with  respect  to  efforts  to  build  the  Company’s  infrastructure.  Development  and  commercialization  of  medical  foods  and  medical  devices  involves  a
lengthy  and  complex  process.  Additionally,  the  Company’s  long-term  viability  and  growth  may  depend  upon  the  successful  development  and
commercialization of products other than Lumega-Z and the MapcatSF. The Company is continuing attempts to raise additional debt and/or equity capital to
fund future operations, but there can be no assurances that the Company will be able to secure such additional financing in the amounts necessary to fully
fund its operating requirements on acceptable terms or at all. If the Company is unable to access sufficient capital resources on a timely basis, the Company
may be forced to reduce or discontinue its technology and product development programs and curtail or cease operations.

F-7

 
 
 
 
 
 
 
 
 
 
 
 
 
 
2.

Summary of Significant Accounting Policies

Basis of Presentation and Use of Estimates

The financial statements have been prepared in conformity with accounting principles generally accepted in the United States of America (“GAAP”). The
preparation of the financial statements in conformity with GAAP requires management to make certain estimates and assumptions that affect the reported
amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and reported amounts of expenses
during the reporting period. Actual results could differ from those estimates.

Fair Value of Financial Instruments

The authoritative guidance with respect to fair value established a fair value hierarchy that prioritizes the inputs to valuation techniques used to measure fair
value  into  three  levels,  and  requires  that  assets  and  liabilities  carried  at  fair  value  be  classified  and  disclosed  in  one  of  three  categories,  as  noted  below.
Disclosure as to transfers into and out of Levels 1 and 2, and activity in Level 3 fair value measurements, is also required.

Level 1.  Observable  inputs  such  as  quoted  prices  in  active  markets  for  an  identical  asset  or  liability  that  the  Company  has  the  ability  to  access  as  of  the
measurement date. Financial assets and liabilities utilizing Level 1 inputs include active-exchange traded securities and exchange-based derivatives.

Level 2.  Inputs,  other  than  quoted  prices  included  within  Level  1,  which  are  directly  observable  for  the  asset  or  liability  or  indirectly  observable  through
corroboration  with  observable  market  data.  Financial  assets  and  liabilities  utilizing  Level  2  inputs  include  fixed  income  securities,  non-exchange  based
derivatives, mutual funds, and fair-value hedges.

Level  3.  Unobservable  inputs  in  which  there  is  little  or  no  market  data  for  the  asset  or  liability  which  requires  the  reporting  entity  to  develop  its  own
assumptions. Financial assets and liabilities utilizing Level 3 inputs include infrequently-traded, non-exchange-based derivatives and commingled investment
funds, and are measured using present value pricing models.

The Company determines the level in the fair value hierarchy within which each fair value measurement falls in its entirety, based on the lowest level input
that is significant to the fair value measurement in its entirety. In determining the appropriate levels, the Company performs an analysis of the assets and
liabilities at each reporting period end.

The Company believes the carrying amount of its financial instruments (consisting of cash, accounts receivable, and accounts payable and accrued liabilities)
approximates fair value due to the short-term nature of such instruments. The fair value of the Company’s convertible notes payable and promissory notes
approximates their carrying value given the interest rates of such notes.

Concentration of Credit Risk and Other Risks and Uncertainties

Cash balances are maintained at large, well-established financial institutions. At times, cash balances may exceed federally insured limits. The Company has
never experienced any losses related to these balances. Insurance coverage limits are $250,000 per depositor at each financial institution. All cash balances
were fully insured at December 31, 2016 and 2015.

Inventories

The Company’s inventories are stated at the lower of weighted-average cost or market. The cost of finished goods and raw materials is determined on a first-
in, first-out basis. The Company evaluates its inventories for obsolescence and recoverability at each reporting period.

F-8

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Property and Equipment

Property and equipment are initially recorded at their historical cost. Depreciation is computed using the straight-line method over the estimated useful lives
of  the  depreciable  assets  (ranging  from  three  to  seven  years).  Leasehold  improvements  are  amortized  on  a  straight-line  basis  over  the  shorter  of  their
estimated useful lives or the remaining lease term.

Impairment of Long-Lived Assets

The  Company  reviews  long-lived  assets,  consisting  of  property  and  equipment,  for  impairment  at  each  fiscal  year  end  or  when  events  or  changes  in
circumstances indicate the carrying value of these assets may exceed their current fair values. Recoverability of assets to be held and used is measured by a
comparison of the carrying amount of an asset to the estimated undiscounted future cash flows expected to be generated by the asset. If the carrying amount
of an asset exceeds its estimated future cash flows, an impairment charge is recognized for the amount by which the carrying amount of the asset exceeds the
fair value of the assets. Assets to be disposed of are separately presented in the balance sheet and reported at the lower of the carrying amount or fair value
less costs to sell, and are no longer depreciated. The Company has not historically recorded any impairment to its long-lived assets. In the future, if events or
market conditions affect the estimated fair value to the extent that a long-lived asset is impaired, the Company will adjust the carrying value of these long-
lived  assets  in  the  period  in  which  the  impairment  occurs.  As  of  December  31,  2016  and  2015,  the  Company  had  not  deemed  any  long-lived  assets  as
impaired, and was not aware of the existence of any indicators of impairment at such dates.

Revenue Recognition

The Company’s revenue is comprised of sales of medical foods and dietary supplements to consumers through a direct sales/credit card process. when the risk
of loss transfers to our customers, and collection of the receivable is reasonably assured, which generally occurs when the product is shipped. A product is not
shipped without an order from the customer and credit acceptance procedures performed.

The Company allows for returns within 30 days of purchase. Product returns for the years ended December 31, 2016 and 2015 were insignificant.

Research and Development Costs

Research and development costs consist primarily of fees paid to consultants and outside service providers, patent fees and costs, and other expenses relating
to the acquisition, design, development and testing of the Company’s medical foods and related products. Research and development expenditures, which
include patent related costs and stock compensation expense, are expensed as incurred and totaled $64,026 and $401,909 for the years ended December 31,
2016 and 2015, respectively.

Patent Costs

The Company is the owner of one issued domestic patent, one pending domestic patent application, and three foreign patent applications in Canada, Europe
and Hong Kong. Due to the significant uncertainty associated with the successful development of one or more commercially viable products based on the
Company's  research  efforts  and  any  related  patent  applications,  patent  costs,  including  patent-related  legal  fees,  filing  fees  and  other  costs,  including
internally  generated  costs,  are  expensed  as  incurred.  During  the  years  ended  December  31,  2016  and  2015,  patent  costs  were  $30,942  and  $26,407,
respectively, and are included in total research and development costs in the statements of operations.

Convertible Notes Payable

When conventional convertible debt is issued with detachable warrants, the proceeds from issuance are allocated to the two instruments based on their relative
fair values. This method is generally appropriate if debt is issued with any other freestanding instrument that is classified in equity.

F-9

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
When the convertible debt instrument includes both detachable instruments such as warrants, and a beneficial conversion option, the proceeds of issuance are
allocated  among  the  convertible  instrument  and  the  other  detachable  instruments  based  on  their  relative  fair  values  as  indicated  above,  and  the  amount
allocated to the convertible instrument is further analyzed to determine if the embedded conversion option has intrinsic value. If the conversion features of
conventional convertible debt provide for a rate of conversion that is below market value, then the conversion option has intrinsic value and this feature is
characterized  as  a  beneficial  conversion  feature  (“BCF”).  The  Company  calculates  an  effective  conversion  price  based  on  the  fair  value  allocated  to  the
convertible instrument divided by the number of conversion shares based upon the conversion terms of the instrument. The resulting calculation or effective
conversion  price  is  used  to  measure  the  intrinsic  value,  if  any,  of  the  embedded  conversion  option.  Stated  differently,  intrinsic  value  is  calculated  at  the
commitment date as the difference between the conversion price (effective or otherwise) and the fair value of the common stock or other securities into which
the security is convertible, multiplied by the number of shares into which the security is convertible.

If the intrinsic value of the BCF is greater than the proceeds allocated to the convertible instrument, the amount of the discount assigned to the BCF is limited
to the amount of the proceeds allocated to the convertible instrument. A BCF is recorded by the Company as a debt discount and in those circumstances, the
convertible debt will be recorded net of the discount related to the BCF. The Company amortizes the discount to interest expense over the life of the debt
using the effective interest rate method or the straight-line method, as an approximation of effective interest amortization.

Stock-Based Compensation

The Company periodically issues stock-based compensation to officers, directors, contractors and consultants for services rendered. Such issuances vest and
expire according to terms established at the issuance date.

Stock-based payments to officers and directors, and to employees which include grants of employee stock options, are recognized in the financial statements
based on their fair values. Stock option grants, which are generally time vested, will be measured at the grant date fair value and charged to operations on a
straight-line basis over the vesting period. The fair value of stock options is determined utilizing the Black-Scholes option-pricing model, which is affected by
several variables, including the risk-free interest rate, the expected dividend yield, the expected life of the equity award, the exercise price of the stock option
as compared to the fair market value of the common stock on the grant date and the estimated volatility of the common stock over the term of the equity
award.

The risk-free interest rate is based on the U.S. Treasury yield curve in effect at the time of grant. Until the Company has established a trading market for its
common stock, estimated volatility is based on the average historical volatilities of comparable public companies in a similar industry. The expected dividend
yield is based on the current yield at the grant date; the Company has never declared or paid dividends on its common stock and has no plans to do so for the
foreseeable future.

The fair value of members’ units or common stock was determined based on management’s judgment. In order to assist management in calculating such fair
value, we retained a third-party valuation firm in determining the value of our Company. The third-party valuation firm’s input was utilized in determining the
related per unit or share valuations of our equity used at December 31, 2016 and 2015. Management used valuations of $1.00 per unit or share in its fair value
calculations for the periods between December 31, 2014 and September 30, 2016, and $0.88 per share for periods after September 30, 2016, respectively,
based on various inputs, including valuation reports prepared by the third-party valuation firm as of December 31, 2016 and 2015. The fully diluted per share
equivalent  price  is  lower  in  2016  than  in  2015  due  to  the  dilutive  effect  of  the  issuance  of  common  shares  as  compensation  during  the  period.  There  are
numerous acceptable ways to estimate company value, including using net tangible assets, a market-based approach, or discounted cash flows. We considered
alternative methods and concluded that due to the lack of suitably comparable market data, the discounted cash flows method was the most appropriate. A
discounted cash flows (i.e. free cash flows to equity) methodology was applied by the third-party valuation firm using multiple years of balance sheet and
income statement projections along with the following primary assumptions:

F-10

 
 
 
 
 
 
 
 
 
 
 
Discount rate
Risk free rate
Rate of return
Sustainable growth rate
Company survival probability
Liquidation value

  Year Ended December 31,

2016

2015

16%   
2.48%   
16%   
5%   
65%   
  $
0 

16%
2.27%
16%
5%
63%
0 

  $

Management considered business and market factors affecting the Company during the twelve-month periods ended December 31, 2016 and 2015, including
capital raising efforts, its proprietary technology, and other factors. Based on this evaluation, management believes that $0.88 and $1.00 per share valuations
are appropriate for accounting purposes at December 31, 2016 and 2015.

The Company accounts for stock option and warrant grants issued and vesting to non-employees in accordance with the authoritative guidance of the FASB
whereas the value of the stock compensation is based upon the measurement date as determined at either a) the date at which a performance commitment is
reached, or b) at the date at which the necessary performance to earn the equity instruments is complete. Non-employee stock-based compensation charges
generally are amortized over the vesting period on a straight-line basis. In certain circumstances where there are no future performance requirements by the
non-employee, grants are immediately vested and the total stock-based compensation charge is recorded in the period of the measurement date.

The  Company  recognizes  stock  compensation  expense  on  stock  or  unit  purchases  at  a  price  less  than  fair  value,  and  for  fully-vested  stock  issued  to
consultants and other service providers, for the excess of fair value of the stock or units over the price paid for the stock or units.

The Company recognizes the fair value of stock-based compensation within its statements of operations with classification depending on the nature of the
services rendered. The Company will issue new shares to satisfy stock option exercises.

Income Taxes

The Company was a limited liability company prior to June 30, 2015, and taxed as a pass-through entity whereby substantially all income tax attributes were
passed through to the individual members, except for the minimum state income tax and an LLC fee based on revenues. As of June 30, 2015, the Company
became a corporation subject to U.S. federal income taxes and California state income taxes.

The Company currently accounts for income taxes under an asset and liability approach for financial accounting and reporting for income taxes. Accordingly,
the Company recognizes deferred tax assets and liabilities for the expected impact of differences between the financial statements and the tax basis of assets
and liabilities.

The Company accounts for uncertainties in income tax law under a comprehensive model for the financial statement recognition, measurement, presentation
and  disclosure  of  uncertain  tax  positions  taken  or  expected  to  be  taken  in  income  tax  returns  as  prescribed  by  GAAP.  The  tax  effects  of  a  position  are
recognized only if it is “more-likely-than-not” to be sustained by the taxing authority as of the reporting date. If the tax position is not considered “more-
likely-than-not” to be sustained, then no benefits of the position are recognized. As of December 31, 2016, the Company had not recorded any liability for
uncertain tax positions. In subsequent periods, any interest and penalties related to uncertain tax positions will be recognized as a component of income tax
expense.

The  Company  records  a  valuation  allowance  to  reduce  its  deferred  tax  assets  to  the  amount  that  is  more  likely  than  not  to  be  realized.  In  the  event  the
Company determines that it would be able to realize its deferred tax assets in the future in excess of its recorded amount, an adjustment to the deferred tax
assets  would  be  credited  to  operations  in  the  period  such  determination  was  made.  Likewise,  should  the  Company  determine  that  it  would  not  be  able  to
realize  all  or  part  of  its  deferred  tax  assets  in  the  future,  an  adjustment  to  the  deferred  tax  assets  would  be  charged  to  operations  in  the  period  such
determination was made.

F-11

 
 
 
 
 
 
 
 
 
   
   
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
Net Loss per Share

The  Company’s  computation  of  basic  and  diluted  net  loss  per  common  share  is  measured  as  net  loss  divided  by  the  weighted  average  common  shares
outstanding during the respective periods, excluding unvested restricted common stock. Shares of restricted stock are included in the basic weighted average
number of common shares outstanding from the time they vest. The Company considers membership units to be equivalent to common shares for purposes of
the computation of net loss per share. Potential common shares such as from unexercised warrants and shares associated with convertible debt outstanding
that have an anti-dilutive effect are excluded from the calculation of diluted net loss per share. The Company’s basic and diluted net loss per share is the same
for  all  periods  presented  because  all  shares  issuable  upon  exercise  of  warrants  and  conversion  of  convertible  debt  outstanding  are  anti-dilutive  as  they
decrease loss per share.

The following table sets forth the number of shares excluded from the computation of diluted loss per share, as their inclusion would have been anti-dilutive:

Warrants
Estimated shares issuable upon conversion of convertible notes payable
Shares issuable upon conversion of convertible preferred stock

Recent Accounting Pronouncements

December 31,

2016
2,923,666     
-     
2,841,930     
5,765,596     

2015
1,345,166 
1,136,519 
- 
2,481,685 

In  May  2014,  the  Financial  Accounting  Standards  Board  (“FASB”)  issued  Accounting  Standards  Update  No.  2014-09  (ASU  2014-09),  Revenue  from
Contracts with Customers. ASU 2014-09 will eliminate transaction- and industry-specific revenue recognition guidance under current GAAP and replace it
with  a  principle  based  approach  for  determining  revenue  recognition.  ASU  2014-09  will  require  that  companies  recognize  revenue  based  on  the  value  of
transferred  goods  or  services  as  they  occur  in  the  contract.  ASU  2014-09  also  will  require  additional  disclosure  about  the  nature,  amount,  timing  and
uncertainty of revenue and cash flows arising from customer contracts, including significant judgments and changes in judgments and assets recognized from
costs incurred to obtain or fulfill a contract. Based on the FASB’s Exposure Draft Update issued on April 29, 2015, and approved in July 2015, Revenue from
Contracts With Customers (Topic 606): Deferral of the Effective Date, ASU 2014-09 is now effective for reporting periods beginning after December 15,
2017, with early adoption permitted only as of annual reporting periods beginning after December 15, 2016, including interim reporting periods within that
reporting period. Entities will be able to transition to the standard either retrospectively or as a cumulative-effect adjustment as of the date of adoption. The
adoption of ASU 2014-09 is not expected to have any impact on the Company’s financial statement presentation or disclosures.

In February 2016, the FASB issued Accounting Standards Update No. 2016-02 (ASU 2016-02), Leases (Topic 842). ASU 2016-02 requires a lessee to record
a right-of-use asset and a corresponding lease liability, initially measured at the present value of the lease payments, on the balance sheet for all leases with
terms longer than 12 months, as well as the disclosure of key information about leasing arrangements. ASU 2016-02 requires recognition in the statement of
operations  of  a  single  lease  cost,  calculated  so  that  the  cost  of  the  lease  is  allocated  over  the  lease  term,  generally  on  a  straight-line  basis.  ASU  2016-02
requires classification of all cash payments within operating activities in the statement of cash flows. Disclosures are required to provide the amount, timing
and uncertainty of cash flows arising from leases. A modified retrospective transition approach is required for lessees for capital and operating leases existing
at, or entered into after, the beginning of the earliest comparative period presented in the financial statements, with certain practical expedients available. ASU
2016-02 is effective for fiscal years beginning after December 15, 2018, including interim periods within those fiscal years. Early application is permitted.
The Company has not yet evaluated the impact of the adoption of ASU 2016-02 on the Company’s financial statement presentation or disclosures.

F-12

 
 
 
 
 
 
 
 
 
 
   
 
   
   
   
 
   
 
 
 
 
 
 
In  March  2016,  the  FASB  issued  Accounting  Standards  Update  No.  2016-09  (ASU  2016-09),  Compensation  -  Stock  Compensation  (Topic  718):
Improvements  to  Employee  Share-Based  Payment  Accounting.  ASU  2016-09  requires,  among  other  things,  that  all  income  tax  effects  of  awards  be
recognized in the statement of operations when the awards vest or are settled. ASU 2016-09 also allows for an employer to repurchase more of an employee's
shares than it can today for tax withholding purposes without triggering liability accounting and allows for a policy election to account for forfeitures as they
occur. ASU 2016-09 is effective for fiscal years beginning after December 15, 2016, including interim periods within those fiscal years. Early adoption is
permitted  for  any  entity  in  any  interim  or  annual  period.  The  adoption  of  ASU  2016-09  is  not  expected  to  have  any  impact  on  the  Company’s  financial
statement presentation or disclosures.

Management does not believe that any other recently issued, but not yet effective, authoritative guidance, if currently adopted, would have a material impact
on the Company’s financial statement presentation or disclosures.

3.

Inventories

Inventories consisted of the following:

Raw materials
Finished goods

4.

Property and Equipment, net

Property and equipment consisted of the following: 

Leasehold improvements
Testing equipment
Furniture and fixtures
Computer equipment
Office equipment

Less accumulated depreciation and amortization

December 31,

2016

2015

40,679    $
3,320     
43,999    $

26,534 
4,029 
30,563 

December 31,

2016

2015

98,357    $
145,503     
15,348     
15,277     
2,694     
277,179     
(163,159)    
114,020    $

98,357 
145,503 
15,189 
12,082 
2,694 
273,825 
(103,030)
170,795 

  $

  $

  $

  $

For  the  years  ended  December  31,  2016  and  2015,  depreciation  and  amortization  expense  was  $60,129  and  $53,741,  respectively,  of  which  $27,490  and
$37,508  was  included  in  research  and  development  expense,  respectively,  and  $32,639  and  $16,233  was  included  in  general  and  administrative  expense,
respectively.

5.

Convertible Notes Payable

Year of issuance:

2010 (due August 2013)
2015 (due May 2017)
Accrued interest

Total principal and interest

Non-current portion of convertible notes payable

Current portion of notes payable

December 31,

2016

2015

25,000    $
-     
19,323     
44,323     
-     
44,323    $

25,000 
500,000 
32,890 
557,890 
516,575 
41,315 

  $

  $

F-13

 
 
 
 
 
 
 
 
 
 
   
 
   
 
 
 
 
 
 
 
 
   
 
   
   
   
   
 
   
   
 
 
 
 
 
 
 
   
     
 
   
   
   
   
 
 
 
Notes Issued in 2016 and Converted

During 2016, the Company issued convertible notes payable in the principal amount of $136,000, with simple interest of 10% per year, due at maturity and an
average term of 8 months. The notes were convertible at a price of $0.60 upon the occurrence of a public company event or upon voluntary election of the
majority of note holders, all as defined in the notes. The holders received warrants, with three-year terms, to purchase 136,000 shares of common stock at an
exercise price of $1.00 per share. The Company recognized a debt discount at the dates of issuance in the aggregate amount of $136,000 related to the relative
fair value of the warrants and beneficial conversion features, which comprised $70,949 related to the intrinsic value of beneficial conversion features and
$65,051 related to the relative fair value of the warrants. The aggregate fair value allocated to the warrants of $65,051 was based on a probability effected
Black-Scholes option pricing model with a stock price of $1.00, volatility of 111% - 113% and risk-free rates of 0.81% - 0.90%.

During 2016, the Company issued 242,878 shares of the Company’s common stock upon the conversion of $145,724 of outstanding principal and interest
pursuant to the terms of the convertible notes. During the year ended December 31, 2016 the Company amortized a total of $136,000 of valuation discount as
interest expense, including applicable portions upon conversion of the notes.

2015 and Prior Issuances

In  July  2010,  the  Company  issued  an  unsecured  convertible  note  payable  in  the  amount  of  $25,000.  The  note  carries  simple  interest  at  a  rate  of  12%  per
annum and became due and payable on August 1, 2013. The outstanding amounts are convertible into shares of common stock of the Company at conversion
prices of $0.08 per share. This note is currently outstanding and past due, and $19,323 of accrued interest is recorded as of December 31, 2016.

In May 2015, the Company issued a convertible note in the principal amount of $500,000, with interest at 5% per year, and a two-year maturity. The note was
convertible within 10 business days after a Going Public Event, which is defined as the occurrence of any of the following:

·

·

·

The  registration  of  any  class  of  securities  of  the  Borrower  pursuant  to  an  effective  registration  statement  under  the  Securities  Act  of  1933,  as
amended;
The registration of any class of securities of the Borrower pursuant to an effective registration statement under the Securities Exchange Act of 1934,
as amended;
The merger by and between the Company and an entity subject to the reporting obligations under the Securities Exchange Act of 1934, as amended,
including both shell and non-shell companies; provided, however, that the Borrower and its equity holders must receive 50% or more of the equity
interest in the Reporting Company immediately after the merger.

Upon conversion of the principal amount of the note, the holder was entitled to an undiluted 4.76% equity interest in the Company (as defined). This note was
fully converted in 2016, as follows:

On December 27, 2016, the Company received a Notice of Effectiveness from the SEC pursuant to its registration of common stock under the Securities Act
of 1933, as amended. On December 31, 2016, the $500,000 note and related accrued interest of $41,644 was converted into 1,408,854 shares of common
stock with a fair value of $1,239,792. Pursuant to ASC 480-10-25-14(b), the Company determined that the note is a conditional obligation to issue a variable
number of shares with a monetary value that varies based on something other than the fair value of the shares, and is appropriately recorded as a liability
under ASC 480-10. Per ASC 480-10-30, obligations to issue a variable number of shares should be measured subsequently at fair value with changes in fair
value recognized in earnings, unless other GAAP specifies another measurement attribute. Due to the terms of the note, at issuance in May 2015 it was not
practicable  to  determine  a  relative  fair  value  for  the  conversion  feature  at  that  time.  On  December  27,  2016,  the  going  public  event  occurred  when  the
Company’s Form S-1 was declared effective by the SEC. On December 31, 2016, the holder converted a total of $500,000 note principal and accrued interest
of $41,644, into 1,408,854 shares of common stock. At December 31, 2016, the Company had an outside valuation firm determine that the market price of the
Company’s  stock  was  $0.88  per  share.  The  fair  value  of  the  note  principal  and  accrued  interest  was  $1,239,792  as  evidenced  by  the  fair  value  of  shares
received upon conversion. Accordingly, at December 31, 2016, the Company recorded a change in fair value expense of $698,147.

F-14

 
 
 
 
 
 
 
 
 
 
 
 
 
As of December 31, 2014, the Company had outstanding $1,137,500 of convertible notes, $237,937 of accrued interest, and $338,510 of unamortized note
discount related to the conversion features and warrants issued to the note holders. In addition, during 2015, the Company issued convertible notes payable in
the principal amount of $42,500, with simple interest of 10 - 12% per year, due at maturity and an average term of 3 years. The notes are convertible at a price
of $0.50 upon the occurrence of a public company event or the next equity financing, or upon voluntary election of the majority of note holders, all as defined
in  the  notes.  Certain  holders  received  warrants  to  purchase  31,687  membership  interests  equal  to  50%  of  the  number  of  membership  units  issued  upon
conversion of the notes, at a price per unit of $0.60 for 50% of the warrants and a price per unit of $0.75 for the remaining 50% of the warrants, with three
year terms and contingent upon the conversion of the related note. The Company recognized a debt discount at the dates of issuance in the aggregate amount
of  $42,500  related  to  the  relative  fair  value  of  the  warrants  and  beneficial  conversion  features,  which  comprised  $25,844  related  to  the  intrinsic  value  of
beneficial conversion features and $16,656 related to the relative fair value of the warrants. The aggregate fair value allocated to the warrants of $16,656 was
based  on  a  probability  effected  Black-Scholes  option  pricing  model  with  a  stock  price  of  $1.50,  volatility  of  104%  -  109%  and  risk-free  rates  of  0.83%  -
1.03%. All of these notes were converted in 2015, as follows:

During 2015, the Company issued 1,793,692 membership units upon the conversion of $986,542 of outstanding principal and interest pursuant to the terms of
the convertible note agreements. Upon conversion, the remaining unamortized debt discount of $119,972 was charged to interest expense. In August 2015, the
Company issued 886,988 shares of the Company’s common stock upon the conversion of $480,833 of outstanding principal and interest pursuant to the terms
of the convertible notes. Upon conversion, the remaining unamortized debt discount of $143,971 was charged to interest expense.

In connection with the 2015 conversion of notes payable, the Company issued 995,926 membership units valued at $1,135,356 to the holders of the notes as
an inducement to convert their notes payable. In addition, as a further inducement to convert the notes, the Company offered to certain holders of the notes
146,000 warrants valued at $165,072 to acquire membership units. The fair value of the warrants was based on a Black-Scholes option pricing model, with a
stock price of $1.14, volatility of 113%, and a risk-free interest rate of 0.97%. In connection with the August 2015 conversion of notes payable, the Company
issued 50,348 shares of its common stock valued at $57,397 to the holders of the notes as an inducement to convert their notes payable, which was calculated
as the excess of the shares actually received over the shares the holder was entitled to receive per the terms of their respective note agreements, multiplied by
the fair value of the Company’s common stock of $1.14 per share. Upon conversion, the remaining unamortized debt discount of $381,009 was charged to
interest expense.

As of December 31, 2014, the Company had Convertible notes payable of $400,000 and accrued interest of $114,693 outstanding from loans provided to the
Company from various related party unit holders. These notes carried simple interest at a rate of 12% per annum and approximate three year terms. In lieu of
the repayment of the principal and accrued interest, the outstanding amounts were convertible into membership units at conversion prices ranging from $0.45
-  $0.55  per  share.  The  debt  discount  associated  with  the  notes  payable  to  related  parties  at  December  31,  2014  of  $62,052  represented  the  unamortized
discount related to beneficial conversion features and outstanding warrants to purchase membership units, which was amortized to interest expense over the
life of the corresponding note payable. These notes were converted in 2015, as follows:

In May 2015, the Company issued 865,602 membership units upon the conversion of $442,493 of outstanding principal and a portion of accrued interest.
Upon conversion, the remaining unamortized debt discount was charged to interest expense. In addition, as an inducement to convert the notes, the Company
offered to certain holders 350,001 warrants valued at $341,785 to acquire membership units. The fair value of the warrants was based on a Black-Scholes
option-pricing model, with a stock price of $1.14, volatility of 113%, a risk-free interest rate of 0.97%, and was recognized as a financing cost.

6.

Promissory Notes

Year of issuance:

2015 (due June 2016)
2016 (due November 2016)
Accrued interest

Total principal and interest

Debt discount – unamortized balance
Promissory notes payable, net

December 31,

2016

2015

-    $
10,000     
251     
10,251     
-     
10,251    $

100,000 
- 
425 
100,425 
(36,018)
64,407 

  $

  $

F-15

 
 
 
 
 
 
 
 
 
 
 
   
     
 
   
   
   
   
 
 
 
2016 Issuances

In 2016, the Company issued $170,000 of promissory notes to various outside investors, with simple interest rates ranging from 4% - 9% and a weighted
average term at issuance of approximately three months. The holders received 187,500 warrants to purchase shares of the Company’s common stock at a price
per share of between $0.25 and $0.50 with three year terms. The Company recognized a debt discount at the dates of issuance in the aggregate amount of
$87,627 related to the relative fair value of the warrants. The aggregate fair value of the warrants of $183,753 was based on a Black-Scholes option-pricing
model with a stock price of $1.00, volatility of 111 - 116%, and risk-free interest rates of 0.91 – 1.06%. In addition, in August of 2016, the Company issued a
$50,000 promissory note to an investor with simple interest of 8% and a term at issuance of two months. The holder received 50,000 warrants to purchase
shares of the Company’s common stock at a price per share of $0.25 with three year terms. The Company recognized a debt discount at the date of issuance in
the aggregate amount of $24,726 related to the fair value of the warrants. The aggregate fair value of the warrants of $48,917 was based on a Black-Scholes
option-pricing model with a stock price of $1.00, volatility of 122%, and a risk-free interest rate of 0.87%. Of the total $220,000 of these notes, $210,000 has
been repaid or converted to common stock in 2016, as follows:

In June of 2016, $100,000 of the promissory notes was repaid to an outside investor. In December 2016, $110,000 in principal plus $5,462 in accrued interest
was converted into 115,462 shares of preferred stock with a fair value of $169,344, resulting in a cost of extinguishment of $53,882. Upon conversion, the
remaining unamortized debt discount was charged to interest expense. The remaining $10,000 note is currently outstanding and past due, and $251 of accrued
interest is recorded as of December 31, 2016.

2015 and Prior Issuances

In November 2015, the Company issued a $100,000 promissory note to an outside investor with a term of six months. The holder received 100,000 warrants
to purchase shares of the Company’s common stock at a price per share of $0.25 and a term of three years. The Company recognized a debt discount at the
date of issuance in the aggregate amount of $49,339 related to the fair value of the warrants. The aggregate fair value of the warrants of $97,392 was based on
a Black-Scholes option-pricing model with a stock price of $1.14, volatility of 101%, and a risk-free interest rate of 1.24%. During the year ended December
31,  2015,  debt  discount  of  $13,321  was  amortized  to  interest  expense.  On  December  31,  2016,  the  promissory  note  for  $100,000  plus  accrued  interest  of
$8,836 was converted into 108,836 shares of preferred stock with a fair value of $159,626, resulting in a cost of extinguishment of $50,790. The remaining of
unamortized debt discount was charged to interest expense.

As  of  December  31,  2014,  the  Company  had  outstanding  promissory  notes  of  $235,000,  accrued  interest  of  $18,158,  and  unamortized  debt  discount  of
$108,049.  In  August  2015,  the  Company  issued  441,358  shares  of  its  common  stock  valued  at  $503,149  upon  the  conversion  of  $260,900  of  outstanding
principal  and  interest.  Upon  conversion,  the  remaining  unamortized  debt  discount  was  charged  to  interest  expense.  The  Company  recognized  a  loss  on
settlement of promissory notes of $242,249.

7.

Promissory Notes – Related Party

Year of issuance:

2015 (due December 2015 through March 2016)
2016 (due September 2016)
Accrued interest

Total principal and interest

Debt discount – unamortized balance
Promissory notes payable – related party, net

2016 Issuances

December 31,

2016

2015

-    $
14,000     
2,805     
16,805     
-     
16,805    $

200,000 
- 
3,872 
203,872 
(54,639)
149,233 

  $

  $

In 2016, the Company issued $140,000 of promissory notes to various related party investors, with a weighted average term at issuance of approximately four
months. The holders received 280,000 warrants to purchase shares of the Company’s common stock at a price per share of between $0.25 and $0.50 with
three-year terms. The Company recognized a debt discount at the dates of issuance in the aggregate amount of $92,671 related to the relative fair value of the
warrants. The aggregate fair value of the warrants of $272,748 was based on a Black-Scholes option-pricing model with a stock price of $1.00, volatility of
109 - 113%, and risk-free interest rates of 0.93 – 1.31%.

F-16

 
 
 
 
 
 
 
 
 
 
 
 
   
     
 
   
   
   
   
 
 
 
 
 
During 2016, $51,000 of the promissory notes were repaid. On December 31, 2016, $75,000 in principal plus $7,833 in accrued interest was converted into
82,834 shares of preferred stock with a fair value of $121,490, resulting in a cost of extinguishment of $38,657. Upon conversion, the remaining unamortized
debt discount was charged to interest expense. The remaining $14,000 note is currently outstanding and past due, and $2,805 of accrued interest is recorded as
of December 31, 2016.

2015 and Prior Issuances

In  2015,  the  Company  issued  $200,000  of  promissory  notes  to  a  related  party  investor,  with  three  month  terms  at  issuance.  The  holder  received  400,000
warrants to purchase shares of the Company’s common stock at a price per share of between $0.25 and $0.50 with three year terms. The Company recognized
a debt discount at the dates of issuance in the aggregate amount of $132,237 related to the fair value of the warrants. The aggregate fair value of the warrants
of $390,292 was based on a Black-Scholes option-pricing model with a stock price of $1.14, volatility of 100 - 105%, and risk-free interest rates of 0.92 –
1.33%. On December 31, 2016, $200,000 in principal plus $28,019 in accrued interest was converted into 228,021 shares of preferred stock with a fair value
of $334,431, resulting in a cost of extinguishment of $106,412. Upon conversion, the remaining unamortized debt discount was charged to interest expense.

8.

Commitments and Contingencies

Operating Lease

In  October  2012,  the  Company  entered  into  a  lease  agreement  for  9,605  square  feet  of  office  and  warehouse  space  commencing  March  1,  2013.  As  of
December 31, 2016, remaining average monthly lease payments were $10,227 through July 2018. Upon entering into the agreement, the Company paid a
deposit of $47,449, of which $36,979 represented prepaid rent. As of December 31, 2016, $10,470 remained on deposit under the lease agreement.

As of December 31, 2016 and 2015, the Company had accrued and deferred rent payable for its office and warehouse facilities under its lease agreement in
the aggregate of $85,399 and $143,077, respectively.

The approximate future minimum lease payments under non-cancelable operating leases at December 31, 2016 are as follows:

Years ending December 31,

2017
2018

  $

   $

121,599 
72,710 
194,309 

Rent expense was $106,217 and $106,217 for the years ended December 31, 2016 and 2015, respectively.

Contingencies

The Company is subject to claims and assessments from time to time in the ordinary course of business. The Company’s management does not believe that
any such matters, individually or in the aggregate, will have a material adverse effect on the Company’s business, financial condition, results of operations or
cash flows.

F-17

 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
9.

Stockholders’ Deficit

As of December 31, 2016, the Company is authorized to issue is 100,000,000 shares of stock, consisting of 90,000,000 shares of common stock with a par
value of $0.001 per share and 10,000,000 shares of preferred stock with a par value of $0.001 per share. At December 31, 2016, the Company had 25,046,438
shares of common stock issued and outstanding, and 1,705,154 shares of preferred stock issued and outstanding.

On October 30, 2015, the Company amended its Certificate of Incorporation to change the par value of its common stock and preferred stock from $0.0001
per share to $0.001 per share.

On June 30, 2015 the Company changed its form of organization from a limited liability company to a corporation under the laws of the State of Delaware
and all LLC membership units were converted to common stock on a one for one basis. The Company was previously governed by the terms and conditions
of the Guardion Health Sciences, LLC Second Amended and Restated Operating Agreement dated January 28, 2012 (the “Operating Agreement”) and had
one  authorized  class  of  units,  and  one  class  of  members  which  consisted  of  four  members.  The  LLC's  business,  property,  and  affairs  were  managed
exclusively by the manager. Members' voting rights were in direct proportion to their Membership Interests.

Preferred Stock

2016

During 2016, the Company sold 1,170,000 shares of the Company’s Series A Senior Convertible Preferred Stock to various investors. The purchase price of
the stock was $1.00 per share, for an aggregate purchase price of $1,170,000. In addition, the Company issued 535,154 shares of its preferred stock with a fair
value of $784,888 upon conversion of $535,149 of notes payable and accrued interest. The stock has a stated value of $1.00 per share and accrues an annual
dividend at the rate of 8% of the stated value, calculated quarterly, to be paid in shares of common stock at the rate of $0.60 per share. Dividends are payable
to holders of record quarterly, on the last business day of each calendar quarter, from the date of issuance, as may be declared by the Board of Directors, and
are cumulative.

At  the  option  of  the  holder,  the  Preferred  Stock  (including  accrued  but  unpaid  dividends)  may  be  converted  into  shares  of  the  Company’s  common  stock
commencing  January  1,  2017  at  $0.60  per  share.  The  Preferred  Stock  (including  accrued  but  unpaid  dividends)  shall  automatically  convert  into  shares  of
common  stock  in  the  event  that  the  Company  receives  gross  proceeds  of  at  least  $4,000,000  in  one  or  more  equity  financing  transactions  subsequent  to
September 30, 2016, or if the ten (10) day Volume Weighted Average Price per share of common stock is $2.00 or more. If not converted by September 30,
2019, the Preferred Stock (including accrued but unpaid dividends) shall automatically and mandatorily convert into shares of common stock at $0.60 per
share.  Such  mandatory  conversion  shall  be  subject  to  either  a  registration  statement  having  been  filed  with  the  Securities  and  Exchange  Commission,
including the common stock underlying the Preferred Stock, and being in effect, or all shares of underlying common stock being saleable under Rule 144
pursuant to the Securities Act without regard to volume limitations.

The issuance of the 1,170,000 shares of convertible preferred stock gave rise to a beneficial conversion feature due to the stated conversion price of $0.60 per
share being less than the market price of the shares at the issuance date as determined by a third-party valuation. The Company accounted for the beneficial
conversion  features  in  accordance  with  ASC  470-20,  Accounting  for  Debt  with  Conversion  and  Other  Options.  The  Company  calculated  a  total  deemed
dividend on the Series A Senior Convertible Preferred Stock of $779,586 at December 31, 2016, which equals the amount by which the estimated fair value
of  the  common  stock  issuable  upon  conversion  of  the  issued  preferred  stock  exceeded  the  proceeds  from  such  issuances.  The  deemed  dividend  on  the
preferred stock is accreted using the effective interest method from the respective issuance dates through the earliest conversion date of January 1, 2017. The
accretion of the deemed dividend for the year ended December 31, 2016 was $760,011. The remaining balance of $19,575, representing the amount allocable
to the January 1, 2017 earliest conversion date, will be accreted in January 2017.

The Preferred Stock will vote with the common stock on an “as converted” basis and has standard anti-dilution rights, exclusive of price protection. Upon any
liquidation,  dissolution  or  winding-up  of  the  Company,  whether  voluntary  or  involuntary,  no  distribution  shall  be  made  to  the  holders  of  any  shares  of
common  stock  of  the  Company  unless,  prior  thereto,  the  holders  of  the  Preferred  Stock  shall  have  received  out  of  the  available  assets  of  the  Company,
whether capital or surplus, an amount equal to 100% of the stated value, plus any accrued and unpaid dividends thereon. If the assets of the Company are
insufficient to pay in full such amounts due the holders of the Preferred Stock, then the entire assets shall be distributed ratably among the holders of the
Preferred Stock in accordance with the respective amounts that would be payable on such shares of Preferred Stock if all amounts payable thereon were paid
in full. The Preferred Stock will be senior to any other classes or series of preferred stock that may subsequently be issued.

F-18

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Preferred shareholders have unlimited piggyback registration rights. Holders of a majority of the shares of Preferred Stock (based on the $1.00 stated value)
outstanding shall have the right to one demand registration during the three (3) years following the effective date of the Company’s registration statement
under  the  Securities  Exchange  Act  of  1934,  so  long  as  at  least  $500,000  of  Preferred  Stock  has  been  sold  in  this  Preferred  Stock  private  placement  and
$250,000 of Preferred Stock is still outstanding. This demand registration right will terminate when all shares of Preferred Stock have been converted into
common stock.

In the event of a merger or acquisition or change in control of the Company, the Preferred Stock (including all accrued but unpaid dividends) will be deemed
converted into shares of common stock immediately prior to the closing of such a transaction.

Sale of the Company’s Series A Senior Convertible Preferred Stock was completed on December 31, 2016. There was no preferred stock issued during the
year ended December 31, 2015.

During the year ended December 31, 2016, the Company declared dividends of $35,018 to its preferred shareholders which were paid through the issuance of
58,377 shares of common stock.

Common Stock

2016

Prior  to  2016,  the  Company  issued  1,260,000  shares  of  restricted  common  stock  to  service  providers  valued  at  $1,435,024,  of  which  $601,344  had  been
recognized as expense.

During  2016,  the  Company  issued  an  additional  145,000  shares  of  restricted  common  stock  for  services  rendered.  These  shares  are  subject  to  vesting
requirements over 9 to 12 months and remain subject to forfeiture if vesting conditions are not met. The aggregate fair value of the stock was $145,348 based
on a valuation per share of $1.00 on the date of grant.

During 2016, the Company recorded $864,752 of expense related to the vested portion of restricted stock issued in 2015 and 2016. As of December 31, 2016,
$111,369 is expected to be recorded in future periods related to the restricted stock.

Additional details of the Company’s restricted common stock are as follows:

Non-vested, December 31, 2014

Issued
Vested
Forfeited

Non-vested, December 31, 2015

Issued
Vested
Forfeited

Non-vested, December 31, 2016

  Number of Shares   

Weighted Average 
Grant Date Fair Value 
Per Share

-    $
1,260,000     
(252,500)    
-     
1,007,500     
145,000     
(800,000)    
-     
352,500    $

- 
1.14 
1.14 
- 
1.14 
1.00 
1.12 
- 
1.13 

During 2016, the Company also issued 595,000 fully vested shares of common stock for services rendered. During the year ended December 31, 2016, the
Company recognized $560,932 in stock compensation expense related to these shares.

F-19

 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
 
 
   
 
 
 
 
During 2016, the Company issued 1,651,732 shares of common stock with a fair value of $1,385,515 upon conversion of notes payable and accrued interest
of $687,368 resulting in a loss on conversion of $698,147.

On December 31, 2016, the Company issued 684,933 shares of common stock with a fair value of $602,741 to our CEO, Michael Favish, in settlement of
$410,960 of previously accrued management and other fees earned by Mr. Favish from December 2013 through December 2016. The difference of $191,781
between the fair value of the shares issued and accrued fees was reflected as additional compensation expense in general and administrative expenses.

2015

During 2015, the Company sold 2,303,227 membership units to two consultants for aggregate cash consideration of $2,303. These membership units had a
fair value of $2,625,679 or $1.14 per unit. Accordingly, the Company recognized $2,623,376 in stock compensation from this transaction in 2015. During
2015, the Company issued 1,459,091 shares of the Company’s common stock for services rendered. The shares were valued in total at $1,662,676, or $1.14
per share.

Warrants

2016

During 2016, in connection with a related party investor’s short-term loan agreements with maturity dates ranging from December 29, 2015 to April 24, 2016,
the Company agreed to issue interest in the form of warrants (the “post-maturity warrants”) in addition to the continued accrual of the stated interest (12%) on
these  loans,  for  which  principal  and  accrued  interest  had  not  been  paid  as  of  December  31,  2016.  The  loans  were  originally  issued  with  accompanying
warrants at a rate of 2 warrants for each dollar of investment. Additional post-maturity warrants were granted monthly, beginning December 30, 2015, at the
rate of 1/10 of the number of original warrant shares held, until the related loans and interest are paid in full. Post-maturity warrants have an exercise price of
$0.25, are immediately vested, and are exercisable for a period of three years. Accordingly, as of December 31, 2016, the Company has granted 585,000 post-
maturity warrants to this investor. The warrants were valued at $575,673, based upon the Black-Scholes option-pricing model, with a stock price of $1.00,
average volatility of 118% and average risk free interest rate of 1.01%. The Company recognized $575,673 of interest expense from this transaction.

In May 2016, the Company issued warrants to purchase 250,000 shares of its common stock, with an exercise price of $0.25 per share, as compensation for
services rendered. The warrants were valued at $246,341, based upon the Black-Scholes option-pricing model, with a stock price of $1.00, volatility of 116%
and a risk-free interest rate of 1.08%. The warrants are fully vested and non-forfeitable. The Company recognized $246,341 in stock compensation from this
transaction, which was recorded in general and administrative expenses in the statement of operations.

In June 2016, the Company issued warrants to purchase 100,000 shares of its common stock, with an exercise price of $0.25 per share, as compensation for
services rendered. The warrants were valued at $98,505, based upon the Black-Scholes option-pricing model, with a stock price of $1.00, volatility of 116%
and a risk-free interest rate of 1.07%. The warrants are fully vested and non-forfeitable. The Company recognized $98,505 in stock compensation from this
transaction, which was recorded in general and administrative expenses in the statement of operations.

A summary of the Company’s warrant activity is as follows: 

December 31, 2014
Granted
Forfeitures
Exercised
December 31, 2015
Granted
December 31, 2016, all exercisable

F-20

Membership
Units or
Shares
1,317,894 
1,832,916 
(782,307)
(1,033,337)
1,335,166 
1,588,500 
2,923,666 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
 
 
 
Additional details of the Company’s outstanding and exercisable warrants are as follows:

Outstanding at:
December 31, 2014
December 31, 2015
December 31, 2016

Membership 
Units or Shares   

Weighted Average 
Exercise Price  
0.37 
0.56 
0.37 

1,317,894    $
1,335,166    $
2,923,666    $

As of December 31, 2016, the Company had an aggregate of 2,923,666 outstanding warrants to purchase shares of its common stock with a weighted average
remaining life of 1.4 years and aggregate intrinsic value of $1,285,712, based upon a stock valuation of $0.88 per share. The intrinsic value is calculated as
the difference between the market value of the underlying common stock and the exercise price of the warrants.

2015

During  2015,  in  connection  with  the  issuance  of  notes  payable  of  $42,500  convertible  at  a  price  of  $0.50  per  membership  unit  upon  certain  events,  the
Company issued 31,687 warrants to purchase membership units equal to 50% of the number of units issued upon conversion of the notes, at a price per unit of
$0.60 for 50% of the warrants and a price per unit of $0.75 for the remaining 50% of the warrants, with three year terms and contingent upon the conversion
of the related notes.

On May 1 2015, the Company issued warrants valued at $506,857 to purchase 496,001 membership units at a weighted average exercise price of $0.21 per
unit with 3 year terms, as inducements to convert notes payable, as more fully described at Note 5 and Note 6.

On May 1, 2015, the Company issued 450,000 membership units to a related party upon exercise of 450,000 warrants at a weighted average exercise price of
$0.20 per unit. In lieu of the aggregate cash payment of $90,000, the holder applied $90,000 of accrued interest towards the exercise price of the warrants.

During 2015, the Company issued 250,001 shares of the Company's common stock upon exercise of 250,001 warrants for aggregate cash consideration of
$75,000. The Company also issued 333,336 shares of the Company's common stock upon exercise of 333,336 warrants at an average exercise price of $0.01
per share. In lieu of the aggregate cash payment of $3,334, the holder applied $3,334 of accrued interest toward the exercise price of the warrants.

On August 10, 2015, the Company issued warrants to purchase 28,176 shares of its common stock at an exercise price of $0.01 per share and a three-year
term in settlement of $15,497 of accounts payable. The warrants were valued at $31,853, based upon the Black-Scholes option-pricing model, with a stock
price of $1.14, volatility of 105% and a risk-free interest rate of 1.09%. The Company recognized a loss on settlement of accounts payable of $16,357.

10.

Related Party Transactions

Due to and from related parties represents unreimbursed expenses and compensation incurred on behalf of, and amounts loaned to the Company by, Michael
Favish, the Company’s Chief Executive Officer, as well as other shareholders. The advances are unsecured, non-interest bearing and are due on demand. As
of December 31, 2016 and 2015, the Company had $91,483 and $286,844, respectively, due to related parties.

The Company paid management fees directly to Michael Favish prior to the Company’s conversion to a corporation. During the first six months of 2015, the
Company  accrued  management  fees  of  $106,250  and  paid  $6,250.  During  the  remaining  six-month  period  ended  December  31,  2015  (subsequent  to
conversion  to  a  corporation  in  June  of  2015),  the  Company  accrued  salary  expense  of  $100,000  and  paid  $0.  During  the  twelve-month  period  ended
December 31, 2016, the Company accrued salary expense of $250,000 and paid $48,500. For all periods presented, accrued amounts are included in general
and administrative expenses.

F-21

 
 
 
 
   
   
   
 
 
 
 
 
 
 
 
 
 
 
 
 
On December 31, 2016, the Company issued 684,933 shares of common stock with a fair value of 602,741 to our CEO, Michael Favish, in settlement of
$410,960 of previously accrued management and other fees earned by Mr. Favish from 2013 through 2016. The difference of $191,781 between the fair value
of the shares issued and accrued fees was reflected as additional compensation in general and administrative expenses.

On December 31, 2016, the Company awarded stock grants to its management and directors as compensation for services rendered. This included 50,000
shares each to Michael Favish, our CEO, Mark Goldstone, a Director, and Robert Weingarten, a Director. 20,000 shares were awarded to Gordon Bethwaite,
our Vice President of Sales and Marketing, 15,000 shares were awarded to Vincent J. Roth, our General Counsel and Corporate Secretary, and 5,000 shares
were awarded to John Townsend, our Controller. All of these shares were fully vested on December 31, 2016. The Company recorded $162,800 of stock-
based compensation as a result of these awards.

As of December 31, 2016, $14,000 of principal and $2,085 of accrued interest was outstanding for a note held by Terrence Favish, son of our CEO, Michael
Favish. The note carries a 12% interest rate.

For  the  year  ended  December  31,  2015,  the  Company  recorded  $2,485,450  of  stock-based  compensation,  for  services  rendered,  to  individuals  that  were
related  parties  at  the  time  of  issuance.  This  included  $1,423,750  recorded  for  stock  issued  to  Robert  Weingarten,  a  director,  $477,714  recorded  for  stock
issued  to  Mark  Goldstone,  a  director,  $285,000  recorded  for  stock  issued  to  Karen  M.  Favish,  wife  of  CEO  Michael  Favish,  $119,419  recorded  for  stock
issued to Gordon Bethwaite, Vice President of Sales & Marketing, $171,000 recorded for stock issued to Vincent J. Roth, General Counsel and Corporate
Secretary, and $8,557 recorded for stock issued to Marie Powell, mother of Karen M. Favish whose investment was purchased on Ms. Powell’s behalf by
Mrs. Favish.

11.

Income Taxes

As of December 31, 2016 and 2015, significant components of the Company’s deferred tax assets were as follows:

Net operating loss carryforwards
Stock-based compensation
Deferred rent
Accrued compensation due to related party
Depreciation
Total deferred tax assets
Valuation allowance
Net deferred tax assets

December 31,

2016
3,356,000    $
2,016,000     
9,000     
-     
1,000     
5,382,000     
(5,382,000)    
-    $

2015
1,414,000 
1,131,000 
11,000 
60,000 
2,000 
2,618,000 
(2,618,000)
- 

  $

  $

In assessing the potential realization of deferred tax assets, management considers whether it is more likely than not that some portion or all of the deferred
tax assets will be realized. The ultimate realization of deferred tax assets is dependent upon the Company attaining future taxable income during the periods in
which those temporary differences become deductible. As of December 31, 2016, management was unable to determine if it is more likely than not that the
Company’s deferred tax assets will be realized, and has therefore recorded an appropriate valuation allowance against deferred tax assets at such dates.

No federal tax provision has been provided for the years ended December 31, 2016 and 2015, due to the losses incurred during the period. Prior to July 1,
2015, the Company operated as a limited liability company, and as such, all profits, losses, revenues, expenses and other income tax attributes were passed
through  to  the  limited  liability  company  owners.  Reconciled  below  is  the  difference  between  the  income  tax  rate  computed  by  applying  the  U.S.  federal
statutory rate and the effective tax rates for the years ended December 31, 2016 and 2015:

U. S. federal statutory tax rate
Net losses passed through to owners while operating as a limited liability company
State taxes, net of Federal benefit
Change in valuation allowance
Effective tax rate

F-22

Year Ended December 31,

2016

2015

(35.0)%   
0.0%    
(6.0)%   
41.0%    
0.0%    

(35.0)%
18.5%
(6.0)%
22.5%
0.0%

 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
   
   
   
   
   
   
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
 
 
 
At December 31, 2016, the Company has available net operating loss carryforwards for federal income tax purposes of approximately $8,234,000 which, if
not  utilized  earlier,  will  begin  to  expire  in  2035.  While  the  Company  has  not  performed  a  formal  analysis  of  the  availability  of  its  net  operating  loss
carryforwards under Internal Revenue Code Sections 382 and 383, management expects that the Company’s ability to use its net operating loss carryforwards
will be limited in future periods.

12.

Subsequent Events

On January 31, 2017, the Company borrowed $100,000 from a related party investor pursuant to an unsecured promissory note, with a 120-day term and a
fixed interest charge of $6,000.

On  March  1,  2017,  the  Company  entered  into  a  non-binding  letter  of  intent  (“LOI”)  with  Vector  Vision,  Inc.,  a  Delaware  corporation  (“VectorVision”),
whereby the parties set forth an outline of the terms and conditions pursuant to which the Company would acquire all of the outstanding shares of stock of
VectorVision  in  exchange  for  a  to  be  determined  number  of  shares  of  common  stock  of  the  Company.  VectorVision  specializes  in  the  standardization  of
contrast sensitivity, glare sensitivity, low contrast acuity, and ETDRS acuity vision testing. The transaction is subject to significant conditions precedent to
closing, including, but not limited to, the satisfactory completion of due diligence, the determination of the amount of purchase consideration, the negotiation
of  definitive  transaction  documents,  the  completion  of  an  audit  of  VectorVision’s  financial  statements,  and  other  matters,  no  later  than  the  June  30,  2017
expiration date of the LOI.

On March 1, 2017, the Company issued 162,500 shares of restricted common stock to a consultant for services rendered.

Between January 1, 2017 and March 13, 2017, the Company issued 700,000 shares of Series B Preferred Stock to investors for an aggregate purchase price of
$700,000. The stock has a stated value of $1.00 per share and accrues an annual dividend at the rate of 6% of the stated value, calculated quarterly, to be paid
in shares of common stock at the rate of $0.75 per share. The Series B Preferred Stock is convertible commencing December 31, 2017, or earlier upon the
approval of the Board of Directors, by the holder into Common Stock at $0.75 per share. The stock is automatically convertible by the Company upon an
equity financing of at least $5,000,000 subsequent to June 30, 2017, or is publicly traded for at least $2.00 per share for 10 consecutive trading days, or upon
completion of a Major Transaction (as defined in the Certificate of Designation). Dividends are payable to holders of record quarterly, on the last business day
of each calendar quarter, from the date of issuance, as may be declared by the Board of Directors, and are cumulative. The Series B Preferred Stock is senior
to all Common Stock and junior to the Series A Preferred Stock. For investors in the Series B offering that previously invested in the Company’s Series A
preferred  stock  offering  in  2016,  the  Company  issued  a  total  of  60,000  warrants  as  additional  incentive  to  invest.  These  warrants  are  fully  vested,  are
immediately exercisable at $0.75 per share, and expire between March 6, 2020 and March 8, 2020.

F-23

 
 
 
 
 
 
 
 
 
 
SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this Report to be signed on its
behalf by the undersigned, thereunto duly authorized on the 30th day of March, 2017.

GUARDION HEALTH SCIENCES, INC.

/s/ Michael Favish

By:
Name: Michael Favish
Title:

Chief Executive Officer

POWER OF ATTORNEY

We, the undersigned officers and directors of GUARDION HEALTH SCIENCES, INC., hereby severally constitute and appoint Michael Favish and Vincent
J. Roth, and each of them (with full power to each of them to act alone), our true and lawful attorneys-in-fact and agents, with full power of substitution, for
us  in  any  and  all  capacities,  to  sign  any  amendments  to  this  Form  10-K,  and  to  file  the  same,  with  exhibits  thereto,  and  other  documents  in  connection
therewith, with the Securities and Exchange Commission, hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them, or their
substitute or substitutes, may lawfully do or cause to be done by virtue thereof.

Pursuant to the requirements of the Securities Exchange Act of 1934, this Report has been signed by the following persons in the capacities and on the dates
indicated.

Signature

/s/ Michael Favish
Michael Favish

/s/ John Townsend
John Townsend

/s/ Robert N. Weingarten
Robert N. Weingarten

/s/ Mark Goldstone
Mark Goldstone

Title

Date

  CEO, President and
  Chairman of the Board

(Principal Executive Officer)

  March 30, 2017

  Controller and Chief Accounting Officer
  (Principal Accounting Officer)

  March 30, 2017

  Director

  Director

52

  March 30, 2017

  March 30, 2017

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
   
   
   
 
   
   
   
   
 
   
   
   
   
 
 
 
INDEX TO EXHIBITS

Exhibit No.

3.1 

3.2 
3.3 
3.4 

3.5 
3.6 
4.1 
4.2 
4.3 
4.4 
4.5 
4.6 
4.7 

4.8 
10.1 
10.2 
10.3 
10.4 
31.1 

31.2 

32.1 

101 

(1)

(2)

(3)

  Description
  Articles of Organization of P4L Health Sciences, LLC and restatement changing name to Guardion Health Sciences, LLC filed in California

(1)

  Articles of Conversion; Delaware and California (1)
  Articles of Incorporation in Delaware and amended thereto (1)
  Certificate of Designation of the Rights, Preferences, Privileges and Restrictions of Series A Convertible Preferred Stock with Certificate of

Correction (2)

  Certificate of Designation of the Rights, Preferences, Privileges and Restrictions of Series B Convertible Preferred Stock (3)
  Bylaws (1)
  May 1, 2015 Promissory Note Purchase Agreement (1)
  May 1, 2015 Promissory Note (1)
  November 30, 2015 Amendment to May 1, 2015 Promissory Note (1)
  November 30, 2015 Promissory Note (1)
  November 30, 2015 Warrant Agreement (1)
  Form of Preferred Stock Purchase Agreement (2)
  Restricted Stock Purchase Agreement by and between Michael Favish Living Trust dated January 31, 2007 and Guardion Health Sciences,

Inc. (2)

  Form of Series B Preferred Stock Purchase Agreement (3)
  Lease for 15150 Avenue of the Sciences, Suite 200, San Diego, CA and amendments thereto (1)
  Form of Restricted Unit Purchase Agreement from Round 3 Funding in 2013 (1)
  Form of Bridge Loan from September 30, 2015 - January 25, 2016 (1)
  Form of Indemnification Agreement (1)
  Certification of Chief Executive Officer pursuant to Rule 13a – 14(a) and 15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-

Oxley Act of 2002

  Certification of Chief Accounting Officer pursuant to Rule 13a – 14(a) and 15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-

Oxley Act of 2002

  Certification of Chief Executive Officer and Chief Accounting Officer pursuant to 18.U.S.C. Section 1350, as adopted pursuant to Section

906 of the Sarbanes Oxley Act of 2002

  The following materials from the Company’s Annual Report on Form 10-K for the year ended December 31, 2016, formatted in XBRL
(eXtensible Business Reporting Language), (i) Consolidated Balance Sheets, (ii) Consolidated Statements of Income, (iii) Consolidated
Statements of Comprehensive Income, (iv) Consolidated Statements of Cash Flows, (v) Consolidated Statement of Stockholders’ Equity and
(vi) Notes to Consolidated Financial Statements

filed  with  the  Registration  Statement  on  Form  S-1  (File  No.  333-209488)  filed  with  the  SEC  on  February  11,  2016  and  incorporated  herein  by
reference.

filed on Form 8-K on January 5, 2017 and incorporated herein by reference.

filed on Form 8-K on March 23, 2017 and incorporated herein by reference.

53

 
 
 
 
 
 
 
 
EXHIBIT 31.1

I, Michael Favish, certify that:

CERTIFICATION

  1.

I have reviewed this annual report on Form 10-K of Guardion Health Sciences, Inc;

 2. Based  on  my  knowledge,  this  report  does  not  contain  any  untrue  statement  of  a  material  fact  or  omit  to  state  a  material  fact  necessary  to  make  the
statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

 3. Based  on  my  knowledge,  the  financial  statements,  and  other  financial  information  included  in  this  report,  fairly  present  in  all  material  respects  the

financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

 4. The  registrant’s  other  certifying  officer(s)  and  I  are  responsible  for  establishing  and  maintaining  disclosure  controls  and  procedures  (as  defined  in
Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f))
for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure
that  material  information  relating  to  the  registrant,  including  its  consolidated  subsidiaries,  is  made  known  to  us  by  others  within  those  entities,
particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision,
to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in
accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness

of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal
quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect,
the registrant’s internal control over financial reporting; and

 5. The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the

registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All  significant  deficiencies  and  material  weaknesses  in  the  design  or  operation  of  internal  control  over  financial  reporting  which  are  reasonably

likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over

financial reporting.

Date:  March 30, 2017

/s/ Michael Favish
Michael Favish
Chief Executive Officer
(Principal Executive Officer)

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
EXHIBIT 31.2

I, John Townsend, certify that:

CERTIFICATION

  1.

I have reviewed this annual report on Form 10-K of Guardion Health Sciences, Inc;

 2. Based  on  my  knowledge,  this  report  does  not  contain  any  untrue  statement  of  a  material  fact  or  omit  to  state  a  material  fact  necessary  to  make  the
statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

 3. Based  on  my  knowledge,  the  financial  statements,  and  other  financial  information  included  in  this  report,  fairly  present  in  all  material  respects  the

financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

 4. The  registrant’s  other  certifying  officer(s)  and  I  are  responsible  for  establishing  and  maintaining  disclosure  controls  and  procedures  (as  defined  in
Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f))
for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure
that  material  information  relating  to  the  registrant,  including  its  consolidated  subsidiaries,  is  made  known  to  us  by  others  within  those  entities,
particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision,
to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in
accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness

of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal
quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect,
the registrant’s internal control over financial reporting; and

 5. The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the

registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All  significant  deficiencies  and  material  weaknesses  in  the  design  or  operation  of  internal  control  over  financial  reporting  which  are  reasonably

likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over

financial reporting.

Date:  March 30, 2017

/s/ John Townsend
John Townsend
Controller and Chief Accounting Officer
(Principal Accounting Officer)

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
EXHIBIT 32.1

CERTIFICATIONS PURSUANT TO
18 U.S.C. SECTION 1350,
AS ENACTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Annual Report of Guardion Health Sciences, Inc. (the “Company”) on Form 10-K for the period ending December 31, 2016 as filed
with the Securities and Exchange Commission on the date hereof (the “Report”), each of Michael Favish, Chief Executive Officer of the Company, and John
Townsend, Controller of the Company, certify, pursuant to 18 U.S.C. § 1350, as enacted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1) The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2) The  information  contained  in  the  Report  fairly  presents,  in  all  material  respects,  the  financial  condition  and  results  of  operations  of  the

Company.

March 30, 2017

March 30, 2017

/s/ Michael Favish
Michael Favish
Chief Executive Officer
(Principal Executive Officer)

/s/ John Townsend          
John Townsend
Controller and Chief Accounting Officer
(Principal Accounting Officer)