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ImmuCell Corporation

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FY2020 Annual Report · ImmuCell Corporation
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UNITED STATES 
SECURITIES AND EXCHANGE COMMISSION 
Washington, D.C. 20549 
________________________ 

FORM 10-K 

________________________ 

ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE  SECURITIES EXCHANGE ACT OF 
1934 

For the fiscal year ended December 31, 2020   

001-12934 
(Commission file number) 

ImmuCell Corporation 

(Exact name of Registrant as specified in its charter) 

Delaware 
(State of incorporation) 

56 Evergreen Drive, Portland, Maine 
(Address of principal executive office) 

01-0382980 
(I.R.S. Employer   
Identification No.) 

04103 
(Zip Code) 

Registrant’s telephone number: (207) 878-2770 

Securities registered pursuant to Section 12(b) of the Act:  None 

Securities registered pursuant to Section 12(g) of the Act: 

Common Stock, par value $0.10 per share 
(Title of class) 

Indicate by check mark if the Registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. 
Yes  No  

Indicate by check mark if the Registrant is not required to file reports pursuant to Section 13 or 15(d) of the Act. Yes 
 No  

Indicate by check mark whether the Registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of 
the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the Registrant 
was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes  
No  

Indicate by check mark whether the Registrant has submitted electronically every Interactive Data File required to 
be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that 
the Registrant was required to submit and post such files). Yes  No  

Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated 
filer, a smaller reporting company or an emerging growth company. Large accelerated filer  Accelerated filer  
Non-accelerated filer  Smaller reporting company  Emerging growth company  

 
 
 
 
 
 
 
 
 
 
 
Indicate by check mark whether the Registrant has filed a report or an attestation to its management’s assessment of the 
effectiveness of its internal control over financial reporting under Section 404(b) of the Sarbanes-Oxley Act (15 USC 
7262(b)) by the independent registered public accounting firm that prepared or issued its audit report. Yes  No  

Indicate by check mark whether the Registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). 
Yes  No  

The aggregate market value of the voting and non-voting common equity held by non-affiliates at June 30, 2020 was 
approximately $29,521,000 based on the closing sales price on June 30, 2020 of $4.73 per share. 

The number of shares of the Registrant’s common stock outstanding at March 19, 2021 was 7,220,836. 

Documents incorporated by reference: Portions of the Registrant’s definitive Proxy Statement to be filed in 
connection with the 2021 Annual Meeting of Stockholders are incorporated by reference into Part III hereof. 

 
 
 
 
ImmuCell Corporation 
TABLE OF CONTENTS 
December 31, 2020 

ITEM 1 

PART I 
Business…………………………………………………………………………………. 

ITEM 1A 

Risk Factors……………………………………………………………………………... 

ITEM 1B 

Unresolved Staff Comments…………………………………………………………….. 

ITEM 2 

Properties……………………………………………………………………………....... 

ITEM 3 

Legal Proceedings……………………………………………………………………….. 

ITEM 4 

ITEM 5 

Mine Safety Disclosures………………………………………………………………… 
PART II 

Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer 
Purchases of Equity Securities………………………………………………………….. 

ITEM 6 

Selected Financial Data…………………………………………………………………. 

ITEM 7 

Management’s Discussion and Analysis of Financial Condition and Results of 
Operations……………………………………………………………………………….. 

ITEM 7A 

Quantitative and Qualitative Disclosures about Market Risk…………………………... 

ITEM 8 

Financial Statements and Supplementary Data…………………………………………. 

ITEM 9 

Changes In and Disagreements With Accountants on Accounting and Financial 
Disclosure……………………………………………………………………………….. 

ITEM 9A 

Controls and Procedures………………………………………………………………… 

ITEM 9B 

Other Information……………………………………………………………………….. 
PART III 

ITEM 10 

Directors, Executive Officers and Corporate Governance……………………………… 

ITEM 11 

Executive Compensation………………………………………………………………... 

ITEM 12 

Security Ownership of Certain Beneficial Owners and Management and   
Related Stockholder Matters……………………………………………………………. 

ITEM 13 

Certain Relationships and Related Transactions, and Director Independence…………. 

ITEM 14 

Principal Accounting Fees and Services………………………………………………... 
PART IV 

1 

11 

18 

18 

19 

19 

19 

20 

20 

32 

32 

32 

33 

33 

33 

34 

35 

35 

35 

ITEM 15 

Exhibits and Financial Statement Schedules……………………………………………. 

36 

Audited Financial Statements……………………………………………………………  F-1 to F-27 

Signatures 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ImmuCell Corporation 
PART I 

ITEM 1 – BUSINESS 

Cautionary Note Regarding Forward-Looking Statements (Safe Harbor Statement): 

This Annual Report on Form 10-K contains “forward-looking statements” within the meaning of Section 27A 
of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Such statements include, but 
are not limited to, any statements relating to: our plans and strategies for our business; projections of future financial 
or operational performance; the timing and outcome of pending or anticipated applications for regulatory approvals; 
factors that may affect the dairy and beef industries and future demand for our products; the extent, nature and 
duration of the COVID-19 pandemic and its consequences, and their direct and indirect impacts on the Company’s 
production activities, operating results and financial condition and on the customers and markets the Company 
serves; the scope and timing of ongoing and future product development work and commercialization of our 
products; future costs of product development efforts; the estimated prevalence rate of subclinical mastitis and 
producers’ level of interest in treating subclinical mastitis given the current economic and market conditions; the 
expected efficacy of new products; estimates about the market size for our products; future market share of and 
revenue generated by current products and products still in development; our ability to increase production output 
and reduce costs of goods sold; the future adequacy of our own manufacturing facilities or those of third parties with 
which we have contractual relationships to meet demand for our products on a timely basis; the impacts of backlogs 
on customer relationships; the anticipated costs of (or time to complete) planned expansions of our manufacturing 
facilities and the adequacy of our funds available for these projects; the continuing availability to us on reasonable 
terms of third-party providers of critical products or services; the robustness of our manufacturing processes and 
related technical issues; estimates about our production capacity, efficiency and yield, which are highly subject to 
biological variability and the product format mix of our sales; the future adequacy of our working capital and the 
availability and cost of third-party financing; future regulatory requirements relating to our products; future expense 
ratios and margins; future compliance with bank debt covenants; costs associated with sustaining compliance with 
current Good Manufacturing Practice (cGMP) regulations in our current operations and attaining such compliance 
for the facility to produce the Nisin Drug Substance; our effectiveness in competing against competitors within both 
our existing and our anticipated product markets; the cost-effectiveness of additional sales and marketing 
expenditures and resources; anticipated changes in our manufacturing capabilities and efficiencies; the value of our 
net deferred tax assets; projections about depreciation expense and its impact on income for book and tax return 
purposes; anticipated market conditions; and any other statements that are not historical facts. Forward-looking 
statements can be identified by the use of words such as “expects”, “may”, “anticipates”, “aims”, “intends”, 
“would”, “could”, “should”, “will”, “plans”, “believes”, “estimates”, “targets”, “projects”, “forecasts”, “seeks” and 
similar words and expressions. In addition, there can be no assurance that future developments affecting us will be 
those that we anticipate. Such statements involve risks and uncertainties, including, but not limited to, those risks 
and uncertainties relating to difficulties or delays in development, testing, regulatory approval, production and 
marketing of our products (including the First Defense® product line and Re-Tain™), competition within our 
anticipated product markets, customer acceptance of our new and existing products, product performance, alignment 
between our manufacturing resources and product demand (including the consequences of backlogs or excess 
inventory buildup), our reliance upon third parties for financial support, products and services, changes in laws and 
regulations, decision making and delays by regulatory authorities, currency values and fluctuations and other risks 
detailed from time to time in filings we make with the Securities and Exchange Commission (SEC), including our 
Quarterly Reports on Form 10-Q, our Annual Reports on Form 10-K and our Current Reports on Form 8-K. Such 
statements involve risks and uncertainties and are based on our current expectations, but actual results may differ 
materially due to various factors, including the risk factors summarized under PART I: ITEM 1A – RISK 
FACTORS of this Annual Report on Form 10-K and uncertainties otherwise referred to in this Annual Report. 

Summary 

ImmuCell Corporation was founded in 1982 and completed an initial public offering of common stock in 1987. 

After achieving approval from the Center for Veterinary Biologics, U.S. Department of Agriculture (USDA) to sell 
First Defense® in 1991, we focused most of our efforts during the 1990’s attempting to develop human product 
applications of the underlying milk protein purification technology. Beginning in 1999, we re-focused our business 
strategy on the First Defense® product line and other products that improve the health and productivity of dairy and 

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ImmuCell Corporation 

beef cattle. The demand for animal protein, that must be produced efficiently while ensuring food quality and safety, 
increases as the human population grows. Further, our products help address the growing human health concern about 
using less antibiotics in food-producing animals. We aim to capitalize on the growth in sales of the First Defense® 
product line (a product that provides significant Immediate Immunity™ to newborn dairy and beef livestock) and to 
revolutionize the mastitis treatment paradigm with Re-Tain™ (formerly Mast Out®), a product we are developing to 
treat this most significant cause of economic loss to the dairy industry. 

During 2000, we began the development of Re-Tain™, our purified Nisin treatment for subclinical mastitis in 

lactating dairy cows. No sales of this product can be made without prior approval of our New Animal Drug 
Application (NADA) by the Center for Veterinary Medicine, U.S. Food and Drug Administration (FDA). We have 
achieved FDA approval for four out of five of the significant regulatory submissions required for product approval, 
and we made the fifth and final submission during the first quarter of 2021. Regulatory achievements to date have 
significantly reduced the product development risks in the areas of safety and effectiveness. Our primary product 
development focus has now turned to completion of the manufacturing objectives required for FDA approval. 

Since 2006, we have made ongoing efforts to maintain compliance with current Good Manufacturing Practice 

(cGMP) regulations in all of our manufacturing operations, which requires a sustained investment that further 
enhances the quality of all of our products and our operating efficiency. As we make process improvements, we 
continue to invest in personnel, equipment and facility modifications to increase the efficiency and quality of our 
operations. 

From the first quarter of 2016 to the first quarter of 2019, we issued an aggregate of 4,037,861 shares of 

common stock, raising net proceeds of approximately $20.5 million in five separate transactions. In order to 
minimize the dilutive effects of these transactions on our existing stockholders, we chose not to issue any form of 
convertible or preferred securities and issued these common shares without any warrants. After refinancing our bank 
debt twice during 2020, we had approximately $9 million in bank debt outstanding under four different credit 
facilities as of December 31, 2020 compared to $8.4 million as of December 31, 2019. This new equity and debt 
capital has been, and is being, used to increase the production capacity for the First Defense® product line and 
complete the development of Re-Tain™ without relying on funding from a partner or licensee, thereby keeping 
control over all product rights and future revenues. 

During the past five years, we have funded our operations, completed a significant capital investment in our 

Drug Substance manufacturing facility for Re-Tain™ and nearly completed a capital investment to increase our 
production capacity for the First Defense® product line. We have also initiated another capital investment to bring 
the formulation and aseptic filling capabilities for Re-Tain™ in house in order to remove our present reliance on an 
outside contractor. The following table displays the changes in the balances of certain accounts over this period (in 
thousands, except for percentages): 

Cash, cash equivalents, short-term  investments 

and long-term investments 

Net working capital 
Total assets 
Stockholders’ equity 
Market capitalization 
Common shares outstanding(1) 

As of December 31, 

2020 

2015 

$ Increase   
Over   
F i v e -   
Year Period 

  % Increase   

Over   
Five-   
Year Period 

$7,946 
$9,946 
$40,350 
$28,266 
$42,952 
7,219 

$6,524 
$7,056 
$14,601 
$10,614 
$23,035 
3,055 

$1,422 
$2,890 
$25,749 
$17,652 
$19,917 
4,164 

22% 
41% 
176% 
166% 
86% 
136% 

(1)  There were approximately 414,000 and 238,000 shares of common stock reserved for issuance under stock options that 
were outstanding as of December 31, 2020 and 2015, respectively. 

Animal Health Products 

The First Defense® product line is manufactured from hyperimmune cows’ colostrum (the antibody rich milk 
that a cow produces immediately after giving birth) utilizing our proprietary vaccines and milk protein purification 

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ImmuCell Corporation 
technologies. The First Defense® product line provides bovine antibodies that newborn calves need but are unable 
to produce on their own immediately after birth. The target disease, calf scours (bovine enteritis), causes diarrhea 
and dehydration in newborn calves and often leads to serious sickness and even death. The First Defense® product 
line is the only USDA-licensed, orally delivered scours preventive product on the market for calves with claims 
against E. coli, coronavirus and rotavirus (three leading causes of scours). A single dose of our product provides a 
measured level of protection proven to reduce mortality and morbidity. Our pre-formed antibody products provide 
Immediate Immunity™ during the first few critical weeks of life when calves need this protection most. Studies 
have shown that calves that scour are more susceptible to other diseases later in life and under-perform calves that 
do not contract scours. The direct, two-part mode-of-action of the First Defense® product line delivers specific 
immunoglobulins at the gut level to immediately protect against disease, while also providing additional antibodies 
that are absorbed into the bloodstream. These circulating antibodies function like a natural timed-release 
mechanism, as they are re-secreted into the gut later to provide extended protection. The First Defense® product line 
is convenient to use. A calf needs to receive only one dose of First Defense® within the first twelve hours after 
birth. The capsule format of this product is stored at room temperature and no mixing is required before it is given to 
the calf. The gel tube formats of this product require refrigeration in accordance with product label indications. We 
are the market leader (in terms of both unit volume and dollar sales) when compared to other calf-level scours 
preventatives but have greater market potential as we gain market share from the dam-level (pre-calving scour 
vaccines) competitors. The third quarter of 2020 marked the 29th anniversary of the original USDA approval of this 
product in 1991. During the fourth quarter of 2020, our cumulative sales of First Defense® since inception exceeded 
26,000,000 doses. We believe that these milestones demonstrate the value of our technology and the long-term 
market acceptance of our product. 

The First Defense® product line continues to benefit from wide acceptance by dairy and beef producers as an 

effective tool to prevent scours (diarrhea) in newborn calves. Our Beyond Vaccination® marketing campaign 
focuses on providing antibodies without vaccination. A 100% vaccine response rate is biologically impossible. The 
First Defense® product line removes the variability associated with a scour vaccine response and instead provides a 
measured level of pre-formed antibodies, protecting each calf with an equal level of scours protection. There is a 
strong link between how we sell our product and the challenges we face in producing it. We know better than most 
how variable a cow’s response is to any vaccine. We see this in every batch of First Defense® that we produce. The 
value in First Defense® is that we adjust for this variability in antibody content, as needed, so the newborn is given 
a steady, equal level of protection with each dose. This technology removes a producer’s reliance on variable 
vaccine responses to generate passive antibody protection and instead protects every calf equally with a measured 
dose of Immediate Immunity™ against the most common scour pathogens. Plus, an effectively treated calf is 
much less likely to require expensive antibiotic treatments or build antibiotic resistance. We are the only 
manufacturer within the scour prevention space offering polyclonal multi-pathogen antibodies. The market is 
learning that the best preventative for scours may not be a vaccine. We are educating the market about the health 
benefits of a measured dose of pre-formed antibodies.     

The product line extension, Tri-Shield First Defense, is the first calf-level, passive antibody product on the 

market with USDA-approved disease claims providing Immediate Immunity™ against each of the three leading 
causes of calf scours (E. coli, coronavirus and rotavirus). This new product achieved USDA approval during the fourth 
quarter of 2017 and was listed with the Organic Materials Research Institute (OMRI) during the first quarter of 2019, 
which means it can be used on organic farms. Tri-Shield combines the E. coli and coronavirus antibodies contained in 
our bivalent product with a measured level of rotavirus antibody in a single-dose gel tube delivery format. This 
unique breadth of claims further differentiates our product from calf-level competitive products on the market that 
contain only one or two of these label claims. The unique virus like particle (VLP) technology that is used in our pro-
duction process increases rotavirus titers in colostrum to a level much greater than traditional vaccine technology can. 
Because it is possible that all farms may not have (or perceive to have) a rotavirus problem, we are continuing to sell 
the bivalent formats of the First Defense product line as options for customers.   

Historically, the most common tool to help combat scours has been to vaccinate the mother cow (dam) with a 
scours vaccine and deliver the antibodies that she produces to the newborn. It is generally believed that only 80% of 
animals respond to a vaccine, which could leave about 20% of calves unprotected. We believe that the variability in a 
cow’s immune response to vaccines creates a sales opportunity for our product. Additionally, our research suggests 
that treatment protocols for dam-level scours vaccine programs are not always followed, leaving even more calves 
compromised. We are competing effectively against these dam-level vaccine products. Our marketing campaign, 

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ImmuCell Corporation 
Beyond Vaccination, emphasizes that by delivering Immediate Immunity™ directly to the calf via the First De-
fense product line, producers can reduce stress-causing injections to the cow. Reliance on a dam-level scours vaccine 
requires that money be spent before it is known whether the cow is carrying a viable, valued calf. With the First De-
fense product line, that investment can be targeted to the calves that are most critical to the operation. This, in turn, 
can free up space in the cow’s vaccination schedule to improve her immune response to vaccines that are critical to 
her health.   

We believe that the long-term growth in sales of the First Defense® product line may reflect, at least in part, 
the success of our strategic decision to invest in additional sales and marketing efforts to help us introduce the ex-
panding First Defense® product line to new customers. Our communications campaign continues to emphasize how 
the unique ability of the First Defense® product line to provide Immediate Immunity™ generates a dependable 
and competitive return on investment for dairy and beef producers. Preventing newborn calves from becoming sick 
helps them to reach their genetic potential and reduces the need to use treatment antibiotics later in life.   

First Defense Technology® is a unique whey protein concentrate that is processed utilizing our proprietary 

colostrum (first milk) protein purification methods, for the nutritional and feed supplement markets without the 
claims of our USDA-licensed product. During 2012, we initiated a limited launch of a gel tube delivery format of 
our First Defense Technology® in a gel solution. We achieved USDA claims for this product format during the 
fourth quarter of 2018 and Canadian approval during the first quarter of 2019, and it is now being sold as Dual-
Force First Defense®. We are selling the same concentrated whey proteins in a bulk powder format (no capsule), 
which is delivered with a scoop and mixed with colostrum for feeding to calves. We are working to achieve USDA 
claims for this product format during 2021. During 2011, Milk Products, LLC of Chilton, Wisconsin launched 
commercial sales of their product, Ultra Start® 150 Plus and certain similar private label products, which are 
colostrum replacers with First Defense Technology® Inside.   

During 2001, we began to offer our own, internally developed California Mastitis Test (CMT). CMT is 

most often used as a quick on-farm diagnostic to determine which quarter of the udder is mastitic. This test can be 
performed at cow-side for early detection of mastitis. CMT products are also made by other manufacturers and are 
readily available to the dairy producer. In connection with our acquisition of certain gel formulation technologies 
during the first quarter of 2016, we acquired private label manufacturing rights covering a feed supplement product 
sold by Genex Cooperative, Inc. of Shawano, WI. 

Sales and Markets 

Our sales and marketing team consists of one vice president, seven regional managers (including one open 
position) and one director of marketing and customer service. The First Defense® product line and CMT are sold 
primarily through major animal health distributors who, in turn, sell to veterinary clinics, fleet stores and direct to 
farms. Sales of the First Defense® product line are normally seasonal, with higher sales expected during the first 
quarter, largely driven by the beef calving season, which runs primarily from January to April, unlike the dairy 
industry in which operations generally calve year round. Warm and dry weather reduces the producer’s perception 
of the need for a disease preventative product like the First Defense® product line. However, heat stress on calves 
caused by extremely hot summer weather can increase the incidence of scours, just as harsher winter weather 
benefits our sales. Other competition for resources that dairy producers allocate to their calf enterprises has been 
increased by the many new products (principally feed supplements) that have been introduced to the calf market. 
Despite the market volatility affecting both milk prices and feed costs, we continue to increase our sales.   

We estimate that the total U.S. market for scours preventative products (including sales of our product) that 

are given to newborn calves (the calf-level market) is approximately $23.4 million per year. With the additional 
claim for our new product (Tri-Shield First Defense®) against rotavirus, we are now competing against the dam-
level vaccine products that are given to the mother cow to increase the antibody level against specific scours-causing 
pathogens in the colostrum that she produces for her newborn. We estimate that the dam-level product category 
covers approximately twice as many calves as the calf-level product segment reaches. We estimate that the total 
domestic addressable market (both calf and dam levels) is approximately $68.1 million per year. 

The majority of our international sales are to Canada. We price our products in U.S. dollars. To the extent that 

the value of the dollar declines with respect to any other currency, our competitive position may be enhanced. 
Conversely, an increase in the value of the dollar in any country in which we sell products may have the effect of 

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ImmuCell Corporation 

increasing the local price of our products, thereby leading to a potential reduction in demand. Generally, our 
international sales have been generated through relationships with in-country distributors that have knowledge of the 
local regulatory and marketing requirements. We are initiating our plan to expand the number of countries to which 
our First Defense® product line is approved for export. Generally, it is our intent to be the holder of these product 
registrations for each country rather than rely on distribution partners to gain and hold these registrations. This is a 
long regulatory process but allows us to maximize the use of our product label claims. We continue our efforts to 
grow sales of the First Defense® product line in North America, where there are approximately 41 million dairy and 
beef cows in the United States and 4.6 million dairy and beef cows in Canada. We believe that significant market 
opportunities exist in other international territories. The statistics above are provided by an industry compilation of 
USDA data for 2021. Industry practices, economic conditions, cause of disease, distribution channels and regulatory 
requirements may differ in these international markets from what we experience in North America, potentially 
making it more difficult or costly for us to generate and sustain sales volumes at profitable margins in these markets. 

We introduced First Defense® into South Korea in 2005 through Medexx Co., Ltd of Gyeonggi-do, Korea and 

its equivalent into Japan in 2007 through NYS Co., Ltd of Iwate, Japan. The business in Japan is currently not 
active, but we are working to resume sales in this territory. We entered into distribution contracts covering certain 
Middle Eastern countries with Triplest for Drugs and Trade of Madaba, Jordan during the first quarter of 2017 (no 
sales have yet been achieved under this contract) and covering Iran with Senikco, LLC of Laguna Niguel, CA during 
the fourth quarter of 2016 (sales have been initiated under this contract). 

With Re-Tain™, we are working to expand our product offerings to include an intramammary treatment for 
subclinical mastitis for the mother cow during lactation. Nisin (the active ingredient in Re-Tain™) is a bacteriocin 
that is not used in human medicines and could alleviate some of the social concerns that the widespread use of 
antibiotics encourages the growth of antibiotic-resistant bacteria (“superbugs”). Mastitis (inflammation of the 
mammary gland) is estimated to cost the U.S. dairy industry approximately $2 billion in economic harm per year, 
which makes it the most costly and common disease affecting the dairy industry. The disease diminishes the saleable 
quantity and overall value of milk, in addition to causing other herd health and productivity losses. While the benefit 
of treating clinical mastitis is widely known, subclinical mastitis (those cases where cows have infected udders, but 
still produce saleable milk) is associated with its own significant economic losses and is recognized as a substantial 
contributor to clinical mastitis cases. There is a growing awareness of the cascade of adverse events and conditions 
associated with subclinical mastitis for both the dairy producer and the milk processor, including reduced or 
foregone milk quality premiums, lower milk production (some have estimated approximately 1,500 pounds of lost 
milk, or about $270 at $18.00 per hundredweight, per infected cow), shorter shelf life for fluid milk, lower yields 
and less flavor for cheese, higher rates of clinical mastitis, lower conception rates, increased abortions and increased 
cull rates. Some industry experts have estimated that subclinical mastitis costs the U.S. dairy industry approximately 
$1 billion per year. 

We believe that Re-Tain™ could revolutionize the way that mastitis is treated by making earlier treatment of 

subclinically infected cows (while these cows are still producing saleable milk) economically feasible by not 
requiring a milk discard during, or for a period of time after, treatment, which would be a significant competitive 
advantage for our product. No other FDA-approved mastitis treatment product on the market can offer this value 
proposition. It is generally current practice to treat mastitis only when the disease has progressed to the clinical stage 
where the milk from an infected cow cannot be sold. Because the milk from cows treated with traditional antibiotics 
must be discarded, most dairy producers simply do not treat subclinically infected cows. The ability to treat such 
cases without a milk discard could revolutionize the way mastitis is managed in a herd. It is common practice to 
move sick cows from their regular herd group to a sick cow group for treatment and the related milk discard. This 
movement causes stress on the cow and a reduction in milk production. Cows treated with our product would not 
have to be moved, allowing this costly drop in production to be avoided. Our product likely will be priced at a 
premium to the traditional antibiotic products currently on the market, which are all sold subject to a milk discard 
requirement. Common milk discard periods cover the duration of treatment and extend from 1.5 to 3 days after last 
treatment, depending on the antibiotic. On average, a cow produces approximately 60 to 80 pounds of milk per day. 
While milk prices vary significantly, at an average value of $18.00 per 100 pounds, a cow produces approximately 
$10.80 to $14.40 worth of milk per day. These estimated figures would result in milk discard costs ranging from 
approximately $37.80 (for 3.5 days of milk at 60 pounds per day) to $158.40 (for 11 days of milk at 80 pounds per 
day) per treated animal. We estimate that the approximate cost to the U.S. dairy industry of this discarded milk may 
be around $300 million per year. These high milk discard costs associated with traditional antibiotic treatments lead 

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ImmuCell Corporation 
producers to only treat mastitis after clinical signs develop. The Re-Tain™ label will be for subclinical mastitis (not 
clinical). Without a milk discard cost, we expect producers to be more motivated to identify and treat cows at the 
subclinical stage. We believe that the product’s value proposition demonstrates a return on investment to the dairy 
producer and the milk processor that will justify a premium over other mastitis treatments on the market today. 

The USDA’s National Animal Health Monitoring System through its Dairy 2014 study suggests that 21% of 

all dairy cows are treated with a mastitis drug, of which approximately 51% are treated with third generation 
cephalosporins. Many fear that the possible overuse of antibiotics in livestock undermines the effectiveness of drugs 
to combat human illnesses and contributes to a rising number of life-threatening human infections from antibiotic-
resistant bacteria, commonly known as “superbugs”. The FDA is committed to addressing this public health risk. 
Citing concerns about untreatable, life-threatening infections in humans, new FDA and European regulations are 
aimed at restricting the use of antibiotics (including cephalosporins) in food animals and at improving milk quality. 
Regulators have recently increased their monitoring of antibiotic residues in milk and meat. During the first quarter 
of 2012, the USDA reduced the allowable level of somatic cell counts (SCC) in milk from 750,000 (cells per 
milliliter) to 400,000 at the individual farm level (not a blended calculation of comingled milk) in order to qualify 
for an EU health certification for export. 

The FDA’s Veterinary Feed Directive (VFD) became effective January 1, 2017, restricting the use of 
medically important antibiotics for performance purposes and requiring more oversight of antibiotic usage in food 
producing animals by a veterinarian, and more changes and restrictions relating to antibiotic usage appear to be 
likely. Several major food processors and retailers have implemented policies addressing this growing public health 
concern. By reducing the risk of antibiotic residues and slowing the development of antibiotic-resistant organisms, 
we can improve food quality and preserve medically important antibiotics for human disease treatment. This would 
not be a concern for Re-Tain™ because Nisin is not used for human health. This current environment is favorable 
to the introduction of our new product as an alternative to traditional antibiotics such as penicillin and 
cephalosporins. We believe that this changing environment of new regulations and public opinion supports the value 
of our ongoing development and commercialization efforts for Re-Tain™. Additionally, we believe that the use of 
our First Defense® product line is consistent with this trend of reducing the use of antibiotics because the prevention 
of calf scours early in life with our purified colostrum antibodies can reduce the need for treatment antibiotics later 
in a calf’s life. 

It is difficult to estimate the potential size of the market for the treatment of subclinical mastitis because 
presently this disease is largely left untreated. We believe that approximately 20-30% of the U.S. dairy herd is 
affected by subclinical mastitis caused by Gram-positive organisms falling within the claim spectrum of our product. 
This compares to approximately 2% of the U.S. herd that is thought to be infected with clinical mastitis, where 
approximately $60 million per year is spent on drug treatments. Finding candidate cows will require farms to obtain 
monthly individual cow somatic cell count (SCC) data through participation in organizations such as the National 
Dairy Herd Information Association (DHIA) or by installing monitors to indicate high SCC cows or a potential 
health event. Only about 50% of cows are on DHIA test today. Similar market opportunities are likely to exist 
outside the U.S. We believe the use of Re-Tain™ could be expanded with additional data to support treatment late 
in lactation and possibly for clinical stage mastitis. We also believe there may be a market for use in small 
ruminates, where the majority of mastitis cases are caused by strep-like organisms aligned with our effectiveness 
data. Given what we believe to be reasonable assumptions, we estimate that the U.S. market potential for first year 
sales of our new product could be approximately $5.8 million and could grow to approximately $36.1 million during 
the fifth year after market launch. However, due to our limited sales and marketing resources and the significant 
challenges inherent in a small company inducing large numbers of producers to quickly embrace a new technology, 
we presently expect actual Re-Tain™ sales to be substantially below those levels, at least in the early stages of the 
Re-Tain™ launch. The amount of sales that we can capture from this estimated market potential and the timing of 
when this can be achieved is very difficult to know, and the actual size of the market for our new product may differ 
materially from our estimates (up or down). We expect the Drug Substance production facility that we constructed 
for approximately $20.8 million to have initial annual production capacity sufficient to meet at least $10 million in 
sales of Re-Tain™ at current production yields. This production capacity estimate does not yet reflect any inventory 
build strategies in advance of product approval or ongoing yield improvement initiatives. Our new facility is 
designed to have enough room to add a second fermentation and recovery portion of the production line to be 
purchased and installed at the cost of approximately $7 million to effectively double production output. We would 
consider making this investment only after commercial acceptance of the product is demonstrated. That being said, 

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ImmuCell Corporation 

we are presently planning to use the space originally intended for the second Drug Substance fermentation and 
recovery production line for the installation of a Drug Product formulation and aseptic filling module. Thus, 
expansion of the estimated annual capacity of the Drug Substance facility beyond approximately $10 million 
(without factoring in potential yield improvements) would now require relocation of the Drug Product formulation 
and aseptic filling module to another facility, or the acquisition and equipping of other Drug Substance production 
facilities at substantial additional cost or alternative manufacturing strategies.   

With a measured approach to expanding our customer-facing staff, it is our objective to increase our current 

annual level of product sales of just over $15 million to approximately $23 million through both continued growth in 
sales of the First Defense® product line and a successful launch of Re-Tain™ as soon as possible. As market 
penetration for both new products is achieved and additional resources are dedicated to production, sales, marketing 
and technical services, our longer-term goal is to exceed the $30 million level of annual product sales as soon as 
possible during the five-year period after the market launch of Re-Tain™. 

Product Development 

The majority of our product development spending has been focused on the development of Re-Tain™, our 
purified Nisin treatment for subclinical mastitis in lactating cows. During the 21-year period that began on January 
1, 2000 and ended on December 31, 2020, we invested an aggregate of approximately $19.8 million (excluding 
depreciation and the capital cost of our Drug Substance production facility) in the development of this product. This 
estimated allocation reflects only direct expenditures and includes no allocation of product development or 
administrative overhead expenses. Approximately $2.9 million of this investment was offset by related product 
licensing revenues and grant income, most of which was earned from 2001 to 2007.   

During 2000, we acquired an exclusive license from Nutrition 21, Inc. (formerly Applied Microbiology Inc. or 

AMBI) to develop and market Nisin-based products for animal health applications, which allowed us to initiate the 
development of Re-Tain™. In 2004, we paid Nutrition 21 approximately $965,000 to buy out this royalty and milestone-
based license to Nisin, thereby acquiring control of the animal health applications of Nisin. Nisin is a well characterized 
substance, having been used in food preservation applications for over 50 years.  Food-grade Nisin, however, cannot be 
used in pharmaceutical applications because of its low purity.  Our Nisin technology includes patented processing and 
purification methods to achieve pharmaceutical-grade purity. 

During 2004, we entered into a product development and marketing agreement with Zoetis (formerly Pfizer 
Animal Health, a division of Pfizer, Inc.) covering this product. That company elected to terminate the agreement in 
2007. We believe that this decision was not based on any unanticipated efficacy or regulatory issues. Rather, we believe 
the decision was primarily driven by a marketing concern relating to their fear that the milk from treated cows could 
interfere with the manufacture of certain cultured dairy products. Due to the zero milk discard feature, there is a risk that 
Nisin from the milk of treated cows could interfere with the manufacture of certain (but not all) commercial cultured 
dairy products, such as some kinds of cheese and yogurt, if a process tank contains a high enough percentage of milk 
from treated cows. The impact of this potential interference ranges from a delay in the manufacturing process (which 
does happen at times for other reasons) to the less likely stopping of a cheese starter culture. Milk from cows that have 
been treated with our product that is sold exclusively for fluid milk products presents no such risk. We worked with 
scientists and mastitis experts to conduct a formal risk assessment to quantify the impact that milk from treated cows 
may have on cultured dairy products. This study concluded that the dilution of milk from treated cows through 
comingling with milk from untreated cows during normal milk hauling and storage practices reduces the risk of 
interference with commercial dairy cultures to a negligible level when the product is used in accordance with the product 
label. Further, we believe that such a premium-priced product will be used selectively, which reduces the risk of cheese 
interference and is consistent with modern “precision dairying” practices that discourage the indiscriminate use of drug 
treatments.   

Subclinical mastitis, and the study required to achieve an effectiveness claim for it, is defined under the 
FDA/Center for Veterinary Medicine Guidance #49: Target Animal Safety and Drug Effectiveness Studies for Anti-
Microbial Bovine Mastitis Products (Lactating and Non-Lactating Cow Products). Trial eligibility requires both 
pretreatment samples to be positive for the mastitis pathogen (except for Staphylococcus aureus and Streptococcus 
agalactiae, where a single pretreatment sample qualifies a cow for enrollment). For all pathogens, both samples 
taken between 14 and 28 days post treatment (and at least 5 days apart) must be negative to be judged a cure. These 
conservative criteria generally result in enrolling cows with chronic subclinical disease, which rarely self-resolves. 

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ImmuCell Corporation 
Milk from cows infected with subclinical mastitis has greater somatic cell counts (SCC), and producers may be paid 
less for this lower quality milk. Cows with subclinical mastitis infections are known to produce less milk, and cows 
that maintain subclinical mastitis across the dry period have been shown to produce significantly less milk. The 
failure to treat subclinical mastitis may result in chronic infections that are unlikely to respond to antibiotic therapy. 
Finally, cows with subclinical mastitis maintain a reservoir of infection within the herd and increase exposure of 
healthy cows to contagious pathogens.   

Our second most important product development initiatives (in terms of dollars invested and, we believe, 
potential market impact) have been focused on other improvements, extensions or additions to our First Defense® 
product line. During the second quarter of 2009 we entered into a perpetual, exclusive license with the Baylor College 
of Medicine covering the underlying rotavirus vaccine technology used to generate the specific antibodies for use 
with animals. We achieved product license approval and initiated market launch of this product, Tri-Shield First 
Defense®, during the fourth quarter of 2017. During the third quarter of 2018, we obtained approval from the 
Canadian Food Inspection Agency to sell Tri-Shield® in Canada. We initiated sales in Canada through our in-
country distributor during the fourth quarter of 2019. We achieved USDA approval of our bivalent gel tube 
formulation (formerly marketed as First Defense Technology®) during the fourth quarter of 2018 and have re-branded 
this product format as Dual-Force First Defense®. We are currently working to establish USDA claims for our bivalent 
bulk powder formulation of First Defense Technology®.   

We are also working to expand our product development pipeline of bacteriocins that can be used as alternatives 

to traditional antibiotics through expansions of our Nisin technology and yield improvements. Subject to the 
availability of resources, we intend to begin new development projects that are aligned with our core competencies 
and market focus. We also remain interested in acquiring, on suitable terms, other new products and technologies that 
fit with our sales focus on the dairy and beef industries. 

Competition 

Our competition in the animal health market includes other biotechnology companies and major animal health 
companies. Most, if not all, of these competitors have substantially greater financial, marketing, manufacturing and 
human resources and more extensive product development capabilities than we do. 

We would consider any company that sells an antibiotic to treat mastitis, such as Boehringer Ingelheim, Merck 
Animal Health and Zoetis, to be among the potential competitors with respect to Re-Tain™. We expect the FDA to 
grant a period of five years of market exclusivity for our product (meaning the FDA would not grant approval to a 
second NADA with the same active drug for a period of five years after the first NADA approval is granted) under 
Section 512(c)(2)F of the Federal Food, Drug, and Cosmetic Act. The Nisin A to which we have exclusive rights for 
animal health applications is produced from our high-yielding, proprietary L. lactis strain and purified to a high 
level, providing us with a level of protection over a competitor that might try to develop a similar product. 

There are several other products on the market (some with claims and some without) that are delivered to 
newborn calves to prevent scours. We believe that the First Defense® product line offers two significant competitive 
advantages. First, only the First Defense® product line provides protection against E. coli, coronavirus and 
rotavirus, three of the leading causes of calf scours. Second, being derived from colostrum, our product offers 
Immediate ImmunityTM through antibodies that both function at the gut level and are absorbed into the blood 
stream for future protection. All formats of our product can be administered immediately after birth and are not 
negatively affected by maternal colostrum. 

Zoetis sells a product that competes directly with the First Defense® product line in preventing scours via oral 

delivery to newborn calves. Their product (Calf-Guard®) is a modified-live virus vaccine. Newborn calves respond 
poorly to vaccines and the immune system must be given time to develop a response to vaccines. Both our product 
and Calf-Guard® carry claims against coronavirus and rotavirus infections, but this competitive product does not 
carry a claim against E. coli infections like our product does. It is common practice to delay colostrum feeding when 
dosing a calf with Calf-Guard® so that the antibodies in the colostrum do not inactivate this vaccine product. There 
is no nutritional or health benefit to withholding milk from newborn calves. In contrast, we encourage the feeding of 
four quarts of high quality colostrum immediately after birth when dosing a calf with our product, which is standard 
practice for good calf health. Because the antibodies in our product would likely work to inactivate a modified-live 
virus vaccine, rendering it useless or less useful, our product label historically included a precaution that First 
Defense® should not be used within five days of such a vaccine. During the first quarter of 2015, the USDA granted 

8 

 
ImmuCell Corporation 
us permission to remove this precaution from our label, and we have done so. We believe that this precaution should 
be required on the Calf-Guard® label to prevent inactivation of that product by First Defense® antibodies or by 
colostrum. Our product is priced at a premium to Calf-Guard®. 

During the fourth quarter of 2016, Merck launched a new competitive product into this market space. This 
product (BOVILIS® Coronavirus) is a modified-live virus intranasal vaccine that carries a claim against coronavirus 
only. 

Around the end of 2019, Elanco Animal Health gave notice to the market that it had discontinued the 
manufacture of its competitive products, Bovine Ecolizer® and Bovine Ecolizer + C20, and subsequently exited the 
market during the first quarter of 2021. This product was the smallest of our three significant calf-level competitors. 

When compared to the other USDA-approved calf-level scours preventatives, we lead in both sales dollars and 

calves treated within the U.S. market. This product category is comprised of the four primary brands discussed 
above that are given either orally or intranasal to newborn dairy and beef calves immediately after birth. With the 
new rotavirus claim for our product (Tri-Shield First Defense®), we are now also competing against dam-level 
vaccine products that are given to the mother cow to increase the antibody level against scours-causing pathogens in 
the colostrum that she produces for her newborn. Those products are sold by Elanco (Scour Bos™), Merck 
(Guardian®) and Zoetis (ScourGuard®). Despite the best-managed dam vaccine program, colostrum quality is 
naturally variable and newborn calves do not always get the antibodies they need from maternal colostrum. We 
believe that the measured dose of antibodies in our product provides more consistent protection than such vaccine 
products. 

We may not be aware of competition that we face, or may face in the future, from other companies. Our 
competitive position will be highly influenced by our ability to attract and retain key scientific, manufacturing, 
managerial and sales and marketing personnel, to develop proprietary technologies and products. We need to obtain 
USDA, FDA or foreign approvals for new products to effectively promote and market our products. We must have 
available properly licensed, efficient and effective raw material and finished product manufacturing resources to 
continue to profitably sell our current products. We currently compete on the basis of product performance, price 
and distribution capability. We continue to monitor our network of independent distributors to maintain our 
competitive position. 

Intellectual Property 

We own a broad collection of intellectual property rights relating to our research, products and processes. This 
includes: patents, copyrights, trademarks, trade dress, trade secrets, know-how and other intellectual property rights 
in the United States and other countries. We believe the ownership of our intellectual property rights is an important 
factor in our business and that our success depends in part on such ownership. We also rely heavily on the innovative 
skills, technical competence and marketing abilities of our personnel. The Nisin A that is produced from our proprie-
tary strain of L. lactis is an essential component of our intellectual property covering Re-Tain™.   

We own: (a) U.S. Patent No. 6,794,181 entitled “Method of Purifying Lantibiotics”, which covers a manufac-
turing process for preparing pharmaceutical-grade Nisin, which was issued in 2004; and (b) U.S. Patent No. 10,023,617 
entitled “Methods and Systems of Producing Pharmaceutical Grade Lantibiotics”, which covers key, novel and propri-
etary aspects of our manufacturing process for preparing pharmaceutical-grade Nisin, and was issued during the third 
quarter of 2018. In the future, we may file additional patent applications for certain products under development. There 
can be no assurance that patents will be issued with respect to any pending or future applications. In some cases, we 
have chosen (and may choose in the future) not to seek patent protection for certain products or processes. In those 
instances, we have sought (and may seek in the future) to maintain the confidentiality of any relevant intellectual 
property and other proprietary rights through operational measures and contractual agreements. 

We  own  numerous  trademarks  and  trade  dress  that  are  very  important  to  our  business,  and  have  several 
trademark and trade dress applications and registrations in the United States, Canada, Iran and Turkey. We own the 
following  U.S.  trademark  registrations:  IMMUCELL,  FIRST  DEFENSE,  FD  FIRST  DEFENSE  (&  Design), 
FIRST  DEFENSE  TECHNOLOGY,  TRI-SHIELD  FIRST  DEFENSE,  TRI-SHIELD  FIRST  DEFENSE  (& 
Design),  YOUR  CALF  CREW,  BEYOND  VACCINATION,  BEYOND  VACCINATION  (&  Design),  CALF 
HERO, DUAL-FORCE, TRI-SHIELD and MAST OUT. We also own U.S. registrations claiming rights in the 
color blue for our blue gel and blue bolus FIRST DEFENSE products. We own a pending U.S. trademark application 

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ImmuCell Corporation 
for  the  RE-TAIN  trademark.  The  United  States  Patent  and  Trademark  Office  refused  registration  of  our 
IMMEDIATE  IMMUNITY  trademark,  which  we  use  extensively  in  connection  with  marketing  of  all  of  our 
products, on the grounds that the mark is generic. Rather than appeal this finding, we are continuing to build our 
common law rights in the brand. The FDA issued a determination that the name, MAST OUT, which we had intended 
to use for our purified Nisin product, is overly promotional. Rather than continuing an appeal of this decision, we 
selected a new product name, RE-TAIN, which was approved by the FDA during the first quarter of 2019.   

Government Regulation 

We believe that we are in compliance with current regulatory requirements relating to our business and 

products. The manufacture and sale of animal health biologicals within the United States is generally regulated by the 
USDA. We have received USDA and Canadian Food Inspection Agency approval for the bolus format of First 
Defense® and for the gel tube formats of Tri-Shield First Defense® and Dual-Force First Defense®. Re-Tain™ is 
regulated by the FDA, which regulates veterinary drugs. Regulations in the European Union will likely require that 
our product be sold subject to a milk discard requirement in that territory, although the duration of the milk discard 
requirement may be shorter than the discard requirement applicable to competitive antibiotic products in that market. 
Comparable agencies exist in foreign countries, and foreign sales of our products will be subject to regulation by such 
agencies. Many countries have laws regulating the production, sale, distribution or use of biological products, and we 
may have to obtain approvals from regulatory authorities in countries in which we propose to sell our products. 
Depending upon the product and its applications, obtaining regulatory approvals may be a relatively brief and 
inexpensive procedure or it may involve extensive clinical tests, incurring significant expenses and an approval 
process of several years’ duration. We generally rely on in-country experts to assist us with or to perform international 
regulatory applications. 

Employees 

We currently employ 61 employees (including 5 part-time employees) in comparison to 54 employees 

(including 3 part-time employees) approximately a year ago. Approximately 35.9 full-time equivalent employees are 
engaged in manufacturing operations, 9.4 full-time equivalent employees in sales and marketing, 7.6 full-time 
equivalent employees in product development activities (primarily supporting facility maintenance and operation, 
regulatory filings and commercial scale-up for Re-Tain™ ) and 5.6 full-time equivalent employees in finance and 
administration. As needed, we augment our staff with contracted temporary employees. All of our employees are 
required to execute non-disclosure and invention assignment agreements (and some are required to execute non-
compete agreements) intended to protect our rights in our proprietary products. We are not a party to any collective 
bargaining agreement and consider our employee relations to be excellent. 

Public Information 

As a reporting company, we file quarterly and annual reports with the Securities and Exchange Commission 

(SEC) on Form 10-Q and Form 10-K. We also file current reports on Form 8-K, whenever events warrant or require 
such a filing. The public may read and copy any materials that we file with the SEC at the SEC’s Public Reference 
Room at 450 Fifth Street, N.W., Washington, D.C. 20549. The public may obtain information on the operation of 
the Public Reference Room by calling the SEC at 1-800-SEC-0330. The SEC maintains an internet site that contains 
reports, proxy and information statements and other information about us that we file electronically with the SEC at 
http://www.sec.gov. Our internet address is http://www.immucell.com. 

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ITEM 1A — RISK FACTORS 

Financial Risks 

ImmuCell Corporation 

Gross margin on product sales: One of our goals is to achieve a gross margin (before related depreciation ex-

penses) as a percentage of total sales close to 50% after the initial launch of new products. Depreciation expense will 
be a larger component of costs of goods sold for Re-Tain™ than it is for the First Defense® product line. Gross 
margins generally improve over time, but this anticipated improvement may not be realized. Many factors discussed 
in this report impact our costs of goods sold. There is a risk that we are not able to achieve our gross margin goals, 
which would adversely affect our operating results and could impact our future operating plans.   

Exposure to interest rates and debt service obligations: Rising interest rates could negatively affect the 
operating costs of dairy and beef producers and thus put further financial pressure on an already stressed business 
sector, which could indirectly affect our business. We removed the direct aspect of this particular exposure to our 
business by refinancing our bank debt to fixed rate notes at 3.5% per annum during the first quarter of 2020. The 
additional debt we incurred to fund the development of Re-Tain™ has significantly increased our debt service costs. 
We are obligated to make principal and interest payments aggregating approximately $1.1 million, $1.1 million and 
$1.2 million during the years ending December 31, 2021, 2022 and 2023, respectively. See Note 10 to the 
accompanying audited financial statements for more information.   

Debt covenants: Our bank debt is subject to certain financial covenants. Prior to the bank debt refinancing that 
we completed during the fourth quarter of 2020, our bank held $1.4 million in escrow (non-current asset). By using 
$624,000 of the proceeds from our bank debt refinancing during the fourth quarter of 2020 to prepay a portion of our 
mortgage loan, we reduced the then outstanding balance of the mortgage loan to 80% of the most recent appraisal 
value, which allowed the bank to release these funds from escrow. We are required to meet a minimum debt service 
coverage ratio set by the bank of 1.35. This debt service coverage ratio was 2.03 and 1.57 for the years ended 
December 31, 2020 and 2019, respectively. Based on our projected financial performance, we may not satisfy this 
annual requirement for the year ending December 31, 2021. There is a risk that we may not be able to reach an 
agreement with our bank to waive this covenant requirement during the first quarter of 2022.   

Projection of net income (loss): Generally speaking, our financial performance can differ significantly from 

management projections, due to numerous factors that are difficult to predict or that are beyond our control. Weaker 
than expected sales of the First Defense® product line could lead to less profits or deeper operating losses. The timing 
of FDA approval of Re-Tain™ and the initiation of commercial sales of that product will have a material impact on 
our net (loss) income during 2021 and 2022. Additionally, this complexity and uncertainty is magnified by the risks 
relating to and arising out of the duration, extent and nature of adverse effects from the COVID-19 pandemic. 

Risks associated with our funding strategy for Re-Tain™: Failure to maintain adequate cash and liquidity to 

support the commercialization of Re-Tain™ is a risk to our business. Achieving FDA approval of our 
pharmaceutical-grade Nisin produced at commercial-scale is the most critical action remaining in front of us on our 
path to U.S. regulatory approval of Re-Tain™. Having completed the construction and equipping of the Drug 
Substance production facility described elsewhere in this report at a cost of approximately $20.8 million, we will 
continue to incur product development expenses to operate and maintain this facility. Absent sufficient sales of Re-
Tain™ at a profitable gross margin, we would be required to fund all debt service costs from sales of the First 
Defense® product line, which would reduce, and could eliminate, our expected profitability going forward and 
significantly reduce our cash flows.   

Uncertainty of market size and product sales estimates: Estimating the size of the total addressable market and 

future sales growth potential for our First Defense® product line is based on our experience and understanding of 
market dynamics but is inherently subjective. Estimating the size of the market for any new product, such as Re-
Tain™, involves more uncertainties than do projections for established products. We do not know whether, or to 
what extent, our products will achieve, maintain or increase market acceptance and profitability. Some of the 
uncertainties surrounding Re-Tain™ include the product’s effectiveness against prevalent pathogens, market 
acceptance, the effect of a premium selling price on market penetration, cost of manufacture and competition from 
new and existing products sold by substantially larger competitors with greater market reach and promotional 
resources. Since Re-Tain™ is a novel approach to treating mastitis, there are many uncertainties with regards to 
how quickly and to what extent we can develop the subclinical mastitis treatment market. Producers’ current 

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ImmuCell Corporation 
practice generally is to treat only clinical mastitis, which has the visual indicator of abnormal milk. We will need to 
change that practice and increase awareness of the importance of treating subclinical disease. This will require the 
producers’ ability and willingness to diagnose without visual indicators. There is a risk that dairy producers and 
processors will not accept this new technology because of the risk that it may negatively effect cheese making if 
present in a high enough concentration in any cheese batch that utilizes a starter culture that is susceptible to Nisin. 
Reducing this risk somewhat is our belief that bacteriocin technology (over traditional antibiotics) is expected to be 
viewed positively. 

Net deferred tax assets: The realizability of our net deferred tax assets is a subjective estimate that is contin-

gent upon many variables. During the second quarter of 2018, we recorded a full valuation allowance against our net 
deferred tax assets that significantly increased our net loss in comparison to other periods. This non-cash expense 
could be reversed, and this valuation allowance could be reduced or eliminated, if warranted by our future profitabil-
ity and projected profitability in the future. We will continue to assess the need for the valuation allowance at each 
quarter. 

Product Risks 

Product risks generally: The sale of our products is subject to production, financial, efficacy, regulatory, 

competitive and other market risks. Elevated standards to achieve and maintain regulatory compliance required to 
sell our products continue to evolve. Failure to achieve acceptable biological yields from our production processes 
can materially increase our costs of goods sold and reduce our production output, leading to an order backlog that 
could adversely affect our customer relationships and operating results. There is no assurance that we will continue 
to achieve market acceptance of the First Defense® product line at a profitable price level or that we can continue to 
manufacture our products at a low enough cost to result in a sufficient gross margin to justify their continued 
manufacture and sale. Similar concerns exist with Re-Tain™ as we bring that product to market, which could be 
heightened by the additional uncertainties associated with introducing a new product requiring a shift in customer 
behavior.   

Reliance on sales of the First Defense® product line: We are reliant on the market acceptance of the First 

Defense® product line to generate product sales and fund our operations. Our business would not have been 
profitable during the nine consecutive years in the period ended December 31, 2007, during the years ended 
December 31, 2012, 2013, 2015 and 2016, during the nine-month period ended September 30, 2017 or during the 
three-month period ended March 31, 2019, without the gross margin that we earned on sales of the First Defense® 
product line.   

Concentration of sales: Sales of the First Defense® product line aggregated 98% and 97% of our total product 
sales during the years ended December 31, 2020 and 2019, respectively. Our primary customers for the majority of 
our product sales (89% during both of the years ended December 31, 2020 and 2019) are in the U.S. dairy and beef 
industries. Product sales to international customers, who are also in the dairy and beef industries, aggregated 11% 
and 10% of our total product sales during the years ended December 31, 2020 and 2019, respectively. The 
concentration of our sales from one product into one market is a risk to our business. The animal health distribution 
segment has been aggressively consolidating over the last few years with larger distributors acquiring smaller 
distributors. A large portion of our product sales (71% and 69% during the years ended December 31, 2020 and 
2019, respectively) was made to two large distributors. A large portion of our trade accounts receivable (75% and 
76% as of December 31, 2020 and 2019, respectively) was due from these two distributors. We have a good history 
with these distributors, but the concentration of sales and accounts receivable with a small number of customers 
does present a risk to us, including risks related to such customers experiencing financial difficulties or altering the 
basis on which they do business with us in a manner unfavorable to us.   

Production capacity constraints: During the second quarter of 2021, we expect to complete an investment of 

approximately $3.5 million to increase our production capacity (in terms of annual sales dollars) for the First 
Defense® product line from approximately $16.5 million to approximately $23 million based on current selling prices 
and estimated production yields. While this capacity expansion investment is currently proceeding on budget, there is 
a risk of cost overruns in any future production expansions that we may undertake, and a risk that we will not be able 
to achieve our production capacity growth objectives on a timely basis, resulting in a continuing or increasing short 
fall in supply to the market. The inability to meet market demand for our products is a risk to our business. The large 
backlog of orders aggregating approximately $1.8 million as of December 31, 2020, as well as any ongoing order 

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ImmuCell Corporation 
backlog, presents a risk that we could lose customers during this period that are not easily regained thereafter, when 
our production capacity is expected to meet or exceed sales demand. Our plan to continue to expand the First 
Defense® product line requires ongoing review of equipment capacity and utilization across the manufacturing value 
stream at the 56 Evergreen Drive facility and our leased facility at 175 Industrial Way, as well as assessment of 
functional obsolescence and reliability of equipment. This review and assessment could identify a need to fund 
unexpected equipment maintenance or replacement costs.   

Product liability: The manufacture and sale of our products entails a risk of product liability. Our exposure to 

product liability is mitigated to some extent by the fact that our products are directed towards the animal health 
market. We have maintained product liability insurance in an amount which we believe is reasonable in relation to 
our potential exposure in this area. We have no history of claims of this nature being made. 

Regulatory Risks 

Regulatory requirements for the First Defense® product line: First Defense® is sold in the United States 
subject to a product license from the Center for Veterinary Biologics, USDA, which was first obtained in 1991, with 
subsequent approvals of line extensions in 2017 and 2018. As a result, our operations are subject to periodic 
inspection by the USDA. The potency of serial lots is directly traceable to the original serial used to obtain the 
product performance claims (the Reference Standard). Due to the unique nature of the label claims, host animal re-
testing is not required as long as periodic laboratory analyses continue to support the stability of stored Reference 
Standard. To date, these analyses have demonstrated strong stability. However, if the USDA were not to approve 
requalification of the Reference Standard, additional clinical studies could be required to meet regulatory 
requirements and allow for continued sales of the product, which could interrupt sales and adversely affect our 
operating results. Territories outside of the United States may require additional regulatory oversight that we may 
not be able to meet with our current facilities, processes and resources.   

Regulatory requirements for Re-Tain™: The commercial introduction of this product in the United States 
requires us to obtain FDA approval. We have disclosed a timeline of events that could lead to potential product 
approval during the period from the fourth quarter of 2021 to the second quarter of 2022. Completing the development 
through to approval of the NADA by the FDA involves risk. While four of the five required Technical Sections have 
been approved, the development process timeline has been extensive (approximately 20 years) and has involved 
multiple commercial production strategies. The first-phased Chemistry, Manufacturing and Controls Technical Section 
was submitted for the Nisin Drug Substance during the first quarter of 2019, and the FDA response was received 
during the third quarter of 2019. We filed the second-phased Drug Substance and Drug Product submission during the 
first quarter of 2021. To reduce the risk associated with this process, we are working with Norbrook Laboratories Ltd 
for alignment of the required validations and Drug Product manufacture and continue to meet with the FDA to align on 
filing strategy and requirements. Our efforts are subject to inspection and approval by the FDA. There remains a risk 
that the required FDA approvals of our product and facilities could be delayed or not obtained. International regulatory 
approvals would be required for sales of Re-Tain™ outside of the United States. 

Economic Risks Pertaining to the Dairy and Beef Industries 

The industry data referred to below is compiled from USDA databases.  

Cattle count: The January count of all cattle and calves in the United States had steadily declined from 97,000,000 
as of January 1, 2007 to 88,500,000 as of January 1, 2014. Then this figure increased each year to reach 94,800,000 as 
of January 1, 2019 before declining to 93,800,000 as of January 1, 2020 and decreasing a little further to 93,600,000 
as of January 1, 2021. Reflecting seasonal trends, this figure was equal to 103,000,000 and 102,900,000 as of July 1, 
2020 and 2019, respectively.   

Herd size: Prior to 1957, there were over 20,000,000 cows in the U.S. dairy herd. Prior to 1986, there were 
over 10,000,000 cows in the U.S. dairy herd. From 1998 through 2020, the size (annual average) of the U.S. dairy herd 
ranged from approximately the low of 9,011,000 in 2004 to the high of 9,399,000 in 2018. This annual average 
dropped to 9,336,000 during 2019 and then increased to 9,388,000 during the year ended December 31, 2020. For the 
month of January 2021, this figure increased significantly to 9,450,000. 

Milk price and feed costs: The dairy market, similar to many others, has been unstable as a result of the 
pandemic. The price paid to producers for milk has been very volatile. Milk was dumped on farms earlier in the year 

13 

 
ImmuCell Corporation 
largely because of the loss of demand for dairy products from closed restaurants and school lunch programs and other 
negative impacts of the pandemic, but conditions have improved since then. The Class III milk price (an industry 
benchmark that reflects the value of product used to make cheese) is an important indicator because it defines our 
customers’ revenue level. This annual average milk price level (measured in dollars per hundred pounds of milk) 
reached its highest point (since these prices were first reported in 1980) during 2014 at $22.34 (peaking at $24.60 in 
September 2014), which price level has never been repeated. During 2019, this milk price average increased by 
16% over 2018 to $16.96. The low price level during 2018 and into the beginning of 2019 was very challenging to the 
profitability of our customers. During the year ended December 31, 2020, this average milk price was equal to $18.16, 
but it was extremely volatile during the year due largely to disruption in demand related to the COVID-19 pandemic. 
The one-month fluctuation of 73% from a low of $12.14 in May to $21.04 in June set an all-time record for variability. 
This milk price increased significantly to $24.54 for July 2020, which is very close to the all-time record high of $24.60 
set in September 2014. Projections about the milk price in 2021 are uncertain. The annual fluctuations in this milk price 
level are demonstrated in the following table: 

Average Class III Milk Price During 
the Years Ended December 31, 

2014 
2015 
2016 
2017 
2018 
2019 
2020 

$22.34 
$15.80 
$14.87 
$16.17 
$14.61 
$16.96 
$18.16 

(Decrease) 
Increase 

(29%) 
(6%) 
9% 
(10%) 
16% 
7% 

The actual level of milk prices may be less important than its level relative to feed costs.  One measure of this 
relationship is known as the milk-to-feed price ratio, which represents the amount of feed that one pound of milk can 
buy. This ratio varies farm-to-farm based on individual operating parameters. The highest annual average this ratio has 
reached since this ratio was first reported in 1985 was 3.64 in 1987. The annual average for this ratio of 1.52 in 2012 
was the lowest recorded since it was first reported in 1985. Since this ratio reached 3.24 in 2005, it has not exceeded 
3.00. The annual average of 2.54 for 2014 was the highest this ratio has been since it was 2.81 in 2007. This ratio 
averaged 2.05 during 2018 and increased to 2.25 during 2019. This ratio increased to 2.31 during the year ended De-
cember 31, 2020. An increase in feed costs also has a negative impact on the beef industry.  The following table demon-
strates the annual volatility and the low values of this ratio recently: 

Average Milk-To-Feed Price Ratio During   
the Years Ended December 31, 

(Decrease) 
Increase 

2014 
2015 
2016 
2017 
2018 
2019 
2020 

2.54 
2.14 
2.26 
2.42 
2.05 
2.25 
2.31 

(16%) 
6% 
7% 
(15%) 
10% 
3% 

Milk cow price: The all-time high value (annual average) for a milk cow was $1,993 during 2015. Since then, 

this annual average value steadily declined to $1,205 during 2019 before increasing to $1,300 during 2020.   

Market volatility: While the number of cows in the U.S. herd and the production of milk per cow directly 
influence the supply of milk, the price for milk is also influenced by very volatile international demand for milk 
products.  Given our focus on the dairy and beef industries, the volatile market conditions and the resulting financial 
insecurities of our primary end users are risks to our ability to maintain and grow sales at a profitable level. These 
factors also heighten the challenge of selling premium-priced animal health products (such as Tri-Shield First 
Defense® and Re-Tain™) into the dairy market.   

14 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Small Size of Company 

ImmuCell Corporation 

Dependence on key personnel: We are a small company with 61 employees (including 5 part-time employees). 

As such, we rely on certain key employees to support multiple operational functions, with limited redundancy in 
capacity. The loss of any of these key employees could adversely affect our operations until a qualified replacement is 
hired and trained. Our competitive position will be highly influenced by our ability to attract, retain and motivate key 
scientific, manufacturing, managerial and sales and marketing personnel.   

Reliance on outside party to provide certain services under contract for us: We are exposed to additional 
regulatory compliance risks through the subcontractors that we choose to work with to produce Re-Tain™, who also 
need to satisfy certain regulatory requirements in order to provide us with the products and services we need. We are 
investing approximately $4 million of the additional capital we raised during the first quarter of 2019 to construct and 
equip our own Drug Product formulation and aseptic filling capability for Re-Tain™ inside our existing Drug 
Substance facility. The objective of this investment is to end our reliance on an outside party to perform these services 
for us. Actual project costs could exceed our current estimates, and we could fail to access adequate funding to 
complete this investment if costs were to increase. Completion of this project could be delayed due to a number of 
factors outside our control, including delays in equipment fabrication, equipment delivery or facility construction. In 
addition, there is a risk that we fail to achieve regulatory approval of the new facility. We face the risk of potential 
supply interruption if we do not effectively manage the end of supply provided from Norbrook for orders placed by 
December 31, 2021 for delivery into the first half of 2022 to align with the new supply from our own formulation and 
aseptic filling facility which we currently expect to be operational during the fourth quarter of 2022 or second quarter 
of 2023. 

Competition from others: Many of our competitors are significantly larger and more diversified in the relevant 

markets than we are and have substantially greater financial, marketing, manufacturing and human resources and 
more extensive product development and sales/distribution capabilities than we do, including greater ability to 
withstand adverse economic or market conditions and declining revenues and/or profitability. Merck and Zoetis, 
among other companies, sell products that compete directly with the First Defense® product line in preventing 
scours in newborn calves. The scours product sold by Zoetis sells for approximately half the price of our product, 
although it does not have an E. coli claim (which ours does). With Tri-Shield First Defense®, we can now compete 
more effectively against vaccines that are given to the mother cow (dam) to improve the quality of the colostrum 
that she produces for the newborn calf. Elanco, Merck and Zoetis provide these dam vaccine products to the market. 
There are many companies competing in the mastitis treatment market, most notably Boehringer Ingelheim, Merck 
and Zoetis. The subclinical mastitis products sold by these large companies are well established in the market and 
are priced lower than what we expect for our product, but all of them involve traditional antibiotics and are sold 
subject to a requirement to discard milk during and for a period of time after treatment (unlike our product that 
carries zero milk discard and zero milk withhold claims). There is no assurance that our products will compete 
successfully in these markets. We may not be aware of other companies that compete with us or intend to compete 
with us in the future. 

Global Risks 

Global COVID-19 pandemic (novel coronavirus, technically known as SARS-CoV-2): The global COVID-19 
pandemic has created, and continues to create, a great deal of uncertainty for us. The positive indications about the 
improving health of the U.S. economy since 2008 and prior to the COVID-19 pandemic have proven to be temporary. 
The COVID-19 pandemic has affected international trade and created a worldwide health and economic crisis. The 
full impact of this viral outbreak on the global economy, and the duration of such impact, is very uncertain at this 
time. Stock market valuations have declined and recovered and remain volatile. There is a risk of a period of 
economic downturn, the severity and duration of which are difficult to know. Prior to the pandemic and the 
responsive federal economic stimulus programs, many feared the United States had taken on too much national debt. 
Now the debt load is significantly higher. The dairy market, similar to many others, has been unstable as a result of 
the pandemic. The price paid to producers for milk has been very volatile. Milk was dumped on farms earlier in the 
year largely because of the loss of demand for dairy products from closed restaurants and school lunch programs and 
other negative impacts of the pandemic, but conditions have improved since then. There is also economic uncertainty 
for beef producers, as the supply chain is interrupted or otherwise adversely affected due to closures of processing 
plants and reduced throughput caused by, among other things, restaurants closing or curtailing their operations. This 
is a very unusual situation for farmers that work so hard to improve production quality and efficiency in order to help 

15 

 
ImmuCell Corporation 
feed a growing population with high-quality and cost-effective proteins. A combination of the conditions, trends and 
concerns summarized above could have a corresponding negative effect on our business and operations, including the 
supply of the colostrum we purchase to produce our First Defense® product line, the demand for our products in the 
U.S. market and our ability to penetrate or maintain a profitable presence in international markets. We could 
experience shortages in key components and needed products, backlogs and production slowdowns due to difficulties 
accessing needed supplies and labor and other restrictions affecting our ability to consistently deliver our products to 
market. Our exposure to this risk is mitigated to some extent by the fact that our supply chain is not heavily dependent 
on foreign manufacturers, by our on-going cross-training of our employees, by our implementation of remote work 
practices (where feasible) and by our early and continued compliance with recommended hygiene and social 
distancing practices. Despite our best efforts and intentions, there is a risk that an employee could become infected 
and could infect others. This could lead to plant shutdowns and production interruptions and have other negative 
economic and health and safety impacts. 

Bovine diseases: The potential for epidemics of bovine diseases such as Foot and Mouth Disease, Bovine 

Tuberculosis, Brucellosis and Bovine Spongiform Encephalopathy (BSE) presents a risk to us and our customers. 
Documented cases of BSE in the United States have led to an overall tightening of regulations pertaining to 
ingredients of animal origin, especially bovine. The First Defense® product line is manufactured from bovine milk 
(colostrum), which is not considered a BSE risk material. Future regulatory action to increase protection of the human 
food supply could affect the First Defense® product line, although presently we do not anticipate that this will be the 
case. 

Risks Pertaining to Common Stock 

Stock market valuation and liquidity: Our common stock trades on The Nasdaq Stock Market (Nasdaq: 
ICCC). Our average daily trading volume is lower than the volume for most other companies and the bid/ask stock 
price spread can be larger and prices can be volatile, which could result in investors facing difficulty selling their 
stock for proceeds that they may expect or desire. Our share price and average trading volume have seen a 
significant increase during the first quarter of 2021, but still most companies in the animal health sector have market 
capitalization values that greatly exceed our current market capitalization of approximately $80.6 million as of 
March 19, 2021. Our product sales during the year ended December 31, 2020 were $15.3 million. This means that 
our market valuation as of March 19, 2021 was equal to approximately 5.25 times our sales during the year ended 
December 31, 2020. Before gross margin from the sale of new products is achieved, our market capitalization may 
be heavily dependent on the perceived potential for growth from our product under development and may therefore 
be negatively affected by the related uncertainties and risks. 

Certain provisions might discourage, delay or prevent a change in control of our Company or changes in our 

management: Provisions of our certificate of incorporation, our bylaws, our Common Stock Rights Plan or Delaware 
law may discourage, delay or prevent a merger, acquisition or other change in control that stockholders may consider 
favorable, including transactions in which stockholders might otherwise receive a premium for their shares of our 
common stock. These provisions may also prevent or frustrate attempts by our stockholders to replace or remove our 
management. These provisions include: 

• 

• 

• 

• 

limitations on the removal of directors;  

advance notice requirements for stockholder proposals and nominations; 

the ability of our Board of Directors to alter or repeal our bylaws; 

the ability of our Board of Directors to refuse to redeem rights issued under our Common Stock Rights 
Plan or otherwise to limit or suspend its operation that would work to dilute the stock ownership of a 
potential hostile acquirer, potentially preventing acquisitions that have not been approved by our 
Board of Directors; and 

•  Section 203 of the Delaware General Corporation Law, which prohibits a publicly-held Delaware cor-
poration from engaging in a business combination with an interested stockholder (generally defined as 
a person which together with its affiliates owns, or within the last three years has owned, 15% of our 
voting stock, for a period of three years after the date of the transaction in which the person became an 
interested stockholder) unless the business combination is approved in a prescribed manner. 

16 

 
ImmuCell Corporation 
The existence of the foregoing provisions and anti-takeover measures could depress the trading price of our 

common stock or limit the price that investors might be willing to pay in the future for shares of our common stock. 
They could also deter potential acquirers of our Company, thereby reducing the likelihood of obtaining a premium 
for our common stock in an acquisition. 

No expectation to pay any dividends or repurchase stock for the foreseeable future: We do not anticipate 
paying any dividends to, or repurchasing stock from, our stockholders for the foreseeable future. Instead, we expect 
to use cash to fund product development costs and investments in our facilities and production equipment, and to 
increase our working capital and to reduce debt. Stockholders must be prepared to rely on market sales of their 
common stock after price appreciation to earn an investment return, which may never occur. Any determination to 
pay dividends in the future will be made at the discretion of our Board of Directors and will depend on our financial 
condition, results of operations, contractual restrictions, restrictions imposed by applicable laws, current and 
anticipated needs for liquidity and other factors our Board of Directors deems relevant. 

Possible dilution: We may need to access the capital markets again and issue additional common stock in 
order to fund our growth objectives, as described elsewhere in this report. Such issuances could have a dilutive 
effect on our existing stockholders. 

Other Risks 

Access to raw materials and contract manufacturing services: Our objective is to maintain more than one 
source of supply for the components used to manufacture and test our products that we obtain from third parties. 
However, there is a risk that we could have difficulty in efficiently acquiring essential supplies. We have significantly 
increased the number of farms from which we purchase colostrum for the First Defense® product line. A significant 
reduction in farm capacity could make it difficult for us to produce enough inventory to meet customer demand. The 
specific antibodies that we purify from colostrum for the First Defense® product line are not readily available from 
other sources. We are and will be dependent on our manufacturing facilities and operations in Portland for the 
production of the First Defense® product line and Re-Tain™. We are and will be dependent on one manufacturer for 
the supply of the syringes used for our gel tube formats of Dual-Force First Defense® and Tri-Shield First Defense® 
and one other manufacturer for the supply of syringes for Re-Tain™. We expect to be dependent on a contract with 
Norbrook for the Drug Product formulation and aseptic filling of our Nisin Drug Substance for orders placed through 
December 31, 2021 with deliveries extending into the first half of 2022. We expect to complete the investment to 
perform these services in-house during 2022 and achieve the required regulatory approval for use by the fourth 
quarter of 2022 or second quarter of 2023. The facility we intend to construct to perform these services in-house will 
be subject to FDA inspection and approval, the outcome and timing of which are not within our control. The potential 
alternative options for these services are narrowed considerably because our product cannot be formulated or filled in 
a facility that also processes traditional antibiotics (i.e., beta lactams). Any significant damage to or other disruption in 
the services at any of these third-party facilities or our own facilities (including due to regulatory non-approval or 
non-compliance) would adversely affect the production of inventory and result in significant added expenses and 
potential loss of future sales. 

Failure to protect intellectual property: In some cases, we have chosen (and may choose in the future) not to 

seek patent protection for certain products or processes. Instead, we have sought (and may seek in the future) to 
maintain the confidentiality of any relevant proprietary technology through trade secrets, operational safeguards and 
contractual agreements. Reliance upon trade secret, rather than patent, protection may cause us to be vulnerable to 
competitors who successfully replicate (knock off) our manufacturing techniques and processes. Additionally, there 
can be no assurance that others may not independently develop similar trade secrets or technology or obtain access to 
our unpatented trade secrets or proprietary technology. Other companies may have filed patent applications and may 
have been issued patents involving products or technologies potentially useful to us or necessary for us to 
commercialize our products or achieve our business goals. If that were to be the case, there can be no assurance that 
we will be able to obtain licenses to such patents on terms that are acceptable to us. There is also a risk that 
competitors could challenge the claims in patents that have been issued to us. 

Increasing dependence on the continuous and reliable operation of our information technology systems: We 

rely on information systems throughout our company. Any disruption of these systems or significant security 
breaches could adversely affect our business. Although we maintain information security policies and employ 
system backup measures and engage in information system redundancy planning and processes, such policies, 

17 

 
ImmuCell Corporation 
measures, planning and processes, as well as our current disaster recovery plan may be ineffective or inadequate to 
address all eventualities. As information systems and the use of software and related applications by us, our business 
partners, suppliers, and customers become more cloud-based, we become inherently more susceptible to 
cyberattacks. There has been an increase in global cybersecurity vulnerabilities and threats, including more 
sophisticated and targeted cyber-related attacks that pose a risk to the security of our information systems and 
networks and the confidentiality, availability and integrity of data and information. There are reports of increased 
activity by hackers and scammers during the COVID-19 pandemic. Any such attack or breach could compromise 
our networks and the information stored thereon could be accessed, publicly disclosed, lost, or stolen. While we 
have invested in our data and information technology infrastructure (including working with an information security 
technology consultant to assess and enhance our security systems and procedures, and periodically training our 
employees in such systems and procedures), there can be no assurance that these efforts will prevent a system 
disruption, attack, or security breach and, as such, the risk of system disruptions and security breaches from a 
cyberattack remains. We have not experienced any material adverse effect on our business or operations as a 
consequence of any such attack or breach but may incur increasing costs in performing the tasks described above. 
Given the unpredictability of the timing, nature and scope of such disruptions and the evolving nature of 
cybersecurity threats, which vary in technique and sources, if we or our business partners or suppliers were to 
experience a system disruption, attack or security breach that impacts any of our critical functions, or our customers 
were to experience a system disruption, attack or security breach via any of our connected products and services, we 
could potentially be subject to production downtimes, operational delays or other detrimental impacts on our 
operations. Furthermore, any access to, public disclosure of, or other loss of data or information (including any of 
our - or our customers’ or suppliers’ - confidential or proprietary information or personal data or information) as a 
result of an attack or security breach could result in governmental actions or private claims or proceedings, which 
could damage our reputation, cause a loss of confidence in our products and services, damage our ability to develop 
(and protect our rights to) our proprietary technologies and have a material adverse effect on our business, financial 
condition, results of operations or prospects. While this exposure is common to all companies, larger companies 
with greater resources may be better able to mitigate this risk than we can.   

ITEM 1B — UNRESOLVED STAFF COMMENTS 

None 

ITEM 2 — PROPERTIES 

We own a 35,000 square foot (approximately) building at 56 Evergreen Drive in Portland, Maine. We 
currently use this space for substantially all of our office and laboratory needs and some of our manufacturing needs 
for our USDA-regulated manufacturing operations. Once our capacity expansion investment for the First Defense® 
product line is completed during the second quarter of 2021, all of our powder filling, gel formulation and assembly 
services will be relocated out of this building, and this space will continue to be used for all of our vaccine 
production, liquid processing and freeze-drying operations. When we originally purchased this building in 1993, its 
size was 15,000 square feet, including 5,000 square feet of unfinished space on the second floor. In 2001, we 
completed a construction project that added approximately 5,200 square feet of new manufacturing space on the first 
floor and approximately 4,100 square feet of storage space on the second floor. In 2007, we built out the 5,000 
square feet of unfinished space on the second floor into usable office space. After moving first floor offices into this 
new space on the second floor, we modified and expanded the laboratory space on the first floor and added 
approximately 2,500 additional square feet of storage space on the second floor. During 2009, we added 350 square 
feet of cold storage space connected to our first floor production area and added an additional 600 square feet to the 
second floor storage area. During the first quarter of 2015, we completed construction of a two-story addition 
connected to our facility to provide us with approximately 7,100 additional square feet for cold storage, production 
and warehouse space for our operations. 

During the fourth quarter of 2015, we exercised an option to acquire land at 33 Caddie Lane in Portland, 

Maine which is near our facility at 56 Evergreen Drive, on which we initiated construction of our Drug Substance 
production facility for Re-Tain™ during the third quarter of 2016. During the fourth quarter of 2017, we obtained a 
certificate of occupancy from the City of Portland for our 16,202 square foot (9,803 on the first floor and 6,399 on 
the second floor) Drug Substance production facility. Our FDA-regulated operations are conducted in this building. 

During the first quarter of 2017, we purchased a 4,114 square foot facility adjacent to the Drug Substance 

18 

 
ImmuCell Corporation 
production facility for Re-Tain™. We are using this warehouse space primarily for storage of inventory, materials 
and equipment. 

During the first quarter of 2017, we entered into a renewable, two-year lease for approximately 1,350 square 

feet of office, warehouse and garage space in New York to support our farm operations. This lease was extended 
through the end of March of 2021. During March of 2021, we entered into a renewable, two-year lease for 
approximately 1,300 square feet of office, storage and parking space in New York.   

We are renting approximately 960 square feet in Minnesota for a sales office through at least June 2021. This 

lease automatically renews for one-year terms unless we or the landlord give 60-days’ notice of a change.   

On September 12, 2019, we entered into a lease covering approximately 14,300 square feet of office and 

warehouse space with a Lease Possession Date of November 15, 2019 and a Lease Commencement Date of 
February 13, 2020 for some of our USDA-regulated manufacturing operations. We have renovated this space to help 
us expand our production capacity for the First Defense® product line. Once our capacity expansion investment for 
the First Defense® product line is completed during the second quarter of 2021, this space will be used for all of our 
powder filling, gel formulation and assembly services. The lease term is ten years with a right to renew for a second 
ten-year term and a right of first offer to purchase. The total lease liability over the initial ten-year term (including 
inflationary adjustments) aggregates approximately $1.3 million before real estate and personal property taxes, 
utilities, insurance, maintenance and related building and operating expenses.   

We maintain property insurance in amounts that approximate replacement cost and a modest amount of 
business interruption insurance. We also maintain access to certain animals, primarily cows as a source of colostrum 
used in the production of the First Defense® product line, through contractual relationships with commercial dairy 
farms. 

ITEM 3 — LEGAL PROCEEDINGS 

In the ordinary course of business, we may become subject to periodic lawsuits, investigations and claims. 
Although we cannot predict with certainty the ultimate resolution of any such lawsuits, investigations and claims 
against us, we do not believe that any pending or threatened legal proceedings to which we are or could become a 
party will have a material adverse effect on our business, results of operations, or financial condition. 

ITEM 4 — MINE SAFETY DISCLOSURES 

None 

PART II 

ITEM 5 — MARKET FOR REGISTRANT’S COMMON EQUITY, RELATED STOCKHOLDER 

MATTERS AND ISSUER PURCHASES OF EQUITY SECURITIES 

Our common stock trades on The Nasdaq Capital Market tier of The Nasdaq Stock Market under the symbol 

ICCC. As of March 19, 2021, we had 15,000,000 common shares authorized and 7,220,836 common shares 
outstanding, and there were approximately 712 shareholders of record. We have not paid dividends on our common 
stock and do not have any present plan or expectation to pay dividends.   

Equity Compensation Plan Information 

The table below summarizes the common stock reserved for issuance upon the exercise of stock options 

outstanding as of December 31, 2020 or that could be granted in the future: 

Equity compensation plans 
approved by stockholders 
Equity compensation plans not 
approved by stockholders 

Number of shares   
to be issued upon exercise of 
outstanding options 

Weighted-average 
exercise price of 
outstanding options 

Number of shares   
remaining  available for  future issuance 
under  stock-based compensation  plans 
(excluding  shares  reflected in first 
column of this table) 

414,000 

— 

19 

$6.38 

— 

123,500 

— 

 
 
 
 
 
 
 
 
Total 

Purchase of Equity Securities   

ImmuCell Corporation 

414,000   

$6.38   

123,500 

            During the fourth quarter of 2020, we accepted, as partial consideration for the exercise of stock options, the 
surrender of 6,583 stock options with a fair market value ranging from $5.94 to $5.99 per share at the time of 
exercise. 

ITEM 6 — SELECTED FINANCIAL DATA 

Not applicable 

ITEM 7 — MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND 

RESULTS OF OPERATIONS 

The following discussion and analysis of our financial condition and results of operations should be read 
together with our financial statements and the related notes and other financial information included in Part II, Item 
8, “Financial Statements and Supplementary Data” of this Annual Report on Form 10-K. Some of the information 
contained in this discussion and analysis or set forth elsewhere in this Annual Report, including information with 
respect to our plans and strategy for our business and related financing, includes forward-looking statements that 
involve risks and uncertainties. One should review Part I, Item 1A — “Risk Factors” of this Annual Report for a 
discussion of some of the important factors that could cause actual results to differ materially from the results, 
objectives or expectations described in or implied by the forward-looking statements contained in the following 
discussion and analysis. 

Liquidity and Capital Resources 

Net cash provided by operating activities improved to $1.3 million during the year ended December 31, 2020 
in comparison to $234,000 during the year ended December 31, 2019. Cash paid for capital expenditures was $4.1 
million and $1.4 million during the years ended December 31, 2020 and 2019, respectively. Our total depreciation 
expense was approximately $2.3 million and $2.2 million during the years ended December 31, 2020 and 2019, 
respectively. We anticipate that depreciation expense, while not affecting our cash flows from operations, will result 
in net operating losses until and unless product sales increase sufficiently to offset these non-cash expenses. Going 
forward, repayments of the indebtedness incurred to fund these capital expenditures and acquire these assets will 
reduce our cash flows. Debt principal payments (exclusive of the $8.3 million used to repay our refinanced bank 
debt during the first quarter of 2020 and $624,000 used to pay down our mortgage loan during the fourth quarter of 
2020) were $633,000 and $861,000 during the years ended December 31, 2020 and 2019, respectively. We are 
obligated to make principal repayments of approximately $768,000, $818,000 and $916,000 under these loans 
during the years ending December 31, 2021, 2022 and 2023, respectively. 

Based on our best estimates and projections, we believe that our cash and cash equivalents, together with gross 

margin anticipated to be earned from ongoing product sales, will be sufficient to meet our most urgent working 
capital and capital expenditure requirements and to finance our ongoing business operations for at least twelve 
months (which is the period of time required to be addressed for such purposes by accounting disclosure standards) 
from the date of this filing. We have funded most of our business operations principally from the gross margin on 
our product sales and equity and debt financings. The table below summarizes the changes in selected, key accounts 
(in thousands, except for percentages): 

Cash, cash equivalents and short-term 

investments   
Net working capital 
Total assets 
Stockholders’ equity 
Common shares outstanding(1) 

As of December 31, 

(Decrease) Increase 

2020 

2019 

Amount 

% 

$7,946 
$9,946   
$40,350   
$28,266   
7,219   

$8,774 
$10,694   
$38,692   
$28,991   
7,213   

($828) 
($748)   
$1,658   
($725)   
6   

(9%) 
(7%) 
4% 
(3%) 
— 

(1) 

There were approximately 414,000 and 389,000 shares of common stock reserved for issuance for stock options that were 

20 

 
 
 
   
 
 
 
 
 
 
 
outstanding as of December 31, 2020 and 2019, respectively. 

ImmuCell Corporation 

From the first quarter of 2016 through the first quarter of 2019, we raised gross proceeds of approximately 

$22.5 million (net proceeds were approximately $20.5 million) from five different common equity transactions 
priced between $5.25 and $7.30 per share. No warrants were issued in connection with any of these transactions, and 
no convertible or preferred securities were issued.   

From 2010 to 2017, we secured five different debt financings with TDBank N.A., each with different maturity 
dates and balloon principal repayment obligations. During the first quarter of 2020, we closed on a debt refinancing 
aggregating $8.6 million plus a line of credit in the amount of $1.0 million with Gorham Savings Bank (GSB). This 
new debt was comprised of a $5.1 million mortgage loan that bears interest at a fixed rate of 3.50% per annum (with 
a 10-year term and 25-year amortization schedule) and a $3.5 million note that bears interest at a fixed rate of 3.50% 
per annum (with a 7-year term and amortization schedule). The refinancing proceeds were used to provide some 
additional working capital, but mostly to refinance $8.3 million of then outstanding bank debt and pay off an interest 
rate swap termination liability of $165,000. This debt refinancing improved our liquidity by lowering our interest 
expense, spreading our principal payments out over a longer time period and eliminating pending balloon principal 
payments that existed under some of the repaid debt. We were required to hold $1.4 million in escrow (a non-current 
asset), which reduced the effective availability of our liquid assets for operational needs by that amount. During the 
fourth quarter of 2020, we closed on a $1.5 million note with GSB that bears interest at a fixed rate of 3.5% per 
annum (with a 7-year term and amortization schedule). We used $624,000 of the proceeds to prepay a portion of the 
then outstanding principal on our mortgage loan, which reduced the then outstanding balance to 80% of the most 
recent appraised value of the property securing the debt, which allowed GSB to release the $1.4 million of funds 
held in escrow. These credit facilities are subject to certain restrictions and financial covenants and are secured by 
substantially all of our assets, including our facility at 56 Evergreen Drive in Portland (which was independently 
appraised at $4.2 million in connection with the 2015 financing and at $3 million in connection with the 2020 
refinancing) and our facility at 33 Caddie Lane in Portland (which was independently appraised at $3.2 million in 
connection with the 2017 financing and at $2.5 million in connection with the 2020 refinancing).We are required to 
meet a minimum debt service coverage ratio set by GSB of 1.35. Our actual debt service coverage ratio was equal to 
2.03 and 1.57 during the years ended December 31, 2020 and 2019, respectively. However, based on current 
projections of our future financial performance, which includes a high level of ongoing product development 
expenses to support Re-Tain™, we may not satisfy this annual requirement for the year ending December 31, 2021. 
We are negotiating an acceptable solution with GSB. 

During June 2020, we received a $500,000 loan from the Maine Technology Institute that is subordinated to 
all other bank debt. The first 27 months of this loan are interest-free with no interest accrual or required principal 
payments. Principal and interest payments at a fixed rate of 5% per annum are due quarterly over the final five years 
of the loan, beginning during the fourth quarter of 2022 and continuing through the third quarter of 2027. The loan 
may be prepaid without penalty at any time. 

Our capital expenditures during the seven-year period from January 1, 2014 to December 31, 2020 are 

described in the following table: 

December 31, 2014 
December 31, 2015 
December 31, 2016 
December 31, 2017 
December 31, 2018 
December 31, 2019 
December 31, 2020 

Total 

Cash Paid During the Years Ended  

A 

$1,041   
1,991   
1,173   
—   
—   
—   
—   
$4,205   

B 

$—   
265   
2,093   
17,686   
1,596   
—   
—   
$21,640   

C 

D 

E 

Total 

$—   
—   
—   
—   
—   
279   
2,938   
$3,217   

$—   
—   
—   
—   
—   
538   
581   
$1,119   

$471   
463   
320   
74   
434   
574   
554   
$2,890   

$1,512    
2,719    
3,586    
17,760    
2,030    
1,391    
4,073    
$33,071    

PROJECT A (which was completed during 2016) included a 7,100 square foot facility addition at 56 
Evergreen Drive and related equipment and cold storage capacity to increase the production capacity for the First 
Defense® product line. During the first quarter of 2016, we completed this investment, increasing our freeze drying 

21 

 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
ImmuCell Corporation 

capacity by 100% and making other improvements to our liquid processing capacity, which increased our annual 
production capacity (in terms of annual sales dollars) to approximately $16.5 million. The actual value of this 
production output varies based on production yields, selling price, product format mix and other factors. This 
investment also included the construction and equipping of a pilot plant for small-scale Drug Substance production 
facility for Re-Tain™ within our First Defense® production facility at 56 Evergreen. Since Project B was 
completed, this space has been used to produce the gel tube formats of the First Defense® product line. One of the 
objectives of Project C is to move the gel tube operations to 175 Industrial Way so that the vacated space can be 
used to double our liquid processing capacity at 56 Evergreen Drive.   

PROJECT B (which was completed during 2018) was related to the Drug Substance production facility for 

Re-Tain™ at 33 Caddie Lane. During the fourth quarter of 2017, we completed construction of the Drug Substance 
production facility. We began equipment installation during the third quarter of 2017, and we completed this 
installation during the third quarter of 2018. The total cost of this investment for the Drug Substance production 
facility and related processing equipment was $20.8 million plus $331,000 for the land and $472,000 for the 
acquisition of an adjacent 4,100 square foot warehouse facility, which is now being used for First Defense® 
operations. 

PROJECT C (which we anticipate completing during the second quarter of 2021) consists of significant 

renovations to a 14,300 square foot leased facility at 175 Industrial Way, some facility modifications at 56 
Evergreen Drive and the necessary production equipment to increase the annual production capacity of the First 
Defense® product line (in terms of annual sales dollars) from approximately $16.5 million to approximately $23 
million. These production capacity projections differ moderately from prior estimates largely because of biological 
yield differences and changes in the product format mix. The actual value of our production output varies based on 
production yields, selling price, product format mix and other factors. This expansion involves a 50% increase in our 
freeze drying capacity and a 100% increase in our liquid processing capacity. Renovations to our leased facility at 
175 Industrial Way to enable this expansion were completed during the second quarter of 2020. A site license 
approval for this new facility was issued by the USDA during the third quarter of 2020. By moving our powder 
filling and assembly services from 56 Evergreen Drive into this new space at 175 Industrial Way, we created space 
at 56 Evergreen Drive for the installation of the expanded freeze drying capacity. We completed that installation 
during the first quarter of 2021. Presently, we are completing the relocation of our gel formulation equipment from 
56 Evergreen Drive to 175 Industrial Way, creating space for the doubling of our liquid processing capacity at 56 
Evergreen Drive. We deferred the implementation of this final phase of the expansion project to the second quarter 
of 2021 in order not to disrupt finished product releases during our peak selling season. Equipment modifications 
and relocations of this nature require a shut down of operations for several weeks to validate the modified equipment 
and achieve USDA approval for its use in its new location. Since this investment was initiated during 2019 and 
through December 31, 2020, we paid approximately $3.2 million towards Project C, leaving an investment of 
approximately $300,000 to complete the investment during the second quarter of 2021. As part of this $3.5 million 
investment, we also have made the facility modifications necessary for a future expansion of our freeze drying 
capacity by an additional 33%, which would increase our annual production capacity from approximately $23 
million to approximately $30 million. The equipment required to achieve this further production capacity increase 
would cost approximately an additional $800,000. We anticipate bringing this further expanded production capacity 
on-line during the second half of 2022 to meet projected growth in sales demand. 

PROJECT D (construction of which we anticipate completing by the end of 2022) is a $4 million budgeted 

investment to bring the formulation and aseptic filling services for Re-Tain™ Drug Product in-house to end our 
reliance on third-party Drug Product manufacturing services. We expect this facility to be operational during 2022. 
Since this investment was initiated during 2019 and through December 31, 2020, we have expended approximately 
$1.1 million towards Project D, leaving an investment of approximately $2.9 million to complete the project during 
2021 and 2022. 

PROJECT E represents other miscellaneous, routine and necessary capital investments and replacements 
during the years. The original budget for the year ended December 31, 2020 of $300,000 was increased to $450,000. 
The budget for 2021 and 2022 is $550,000 per year. 

We have set aside approximately $4.3 million of the $7.9 million of the cash we had on hand as of December 

31, 2020 to complete the investments in Projects C and D and to fund Project E for 2021 and 2022. We plan to 
complete our $3.5 million investment to increase our production capacity so that we can fill the backlog of orders, 

22 

 
 
 
 
ImmuCell Corporation 

meet ongoing demand and use any excess production to build inventory stocks by the end of 2021. This will also 
require that we invest some available cash in inventory. Our inventory balances were $2.1 million and $2.5 million 
as of December 31, 2020 and 2019, respectively. Our inventory balances consisted of approximately 1% and 21% 
finished goods as of December 31, 2020 and 2019, respectively. See Note 5 to the accompanying audited financial 
statements for more details about our inventory. 

During the third quarter of 2016, the City of Portland approved a Tax Increment Financing (TIF) credit 
enhancement package that reduces the real estate taxes on our Drug Substance production facility for Re-Tain™ by 
65% over the eleven-year period beginning on July 1, 2017 and ending June 30, 2028 and by 30% during the year 
ending June 30, 2029, at which time the rebate expires. During the second quarter of 2017, the TIF was approved by 
the Maine Department of Economic and Community Development. The value of the tax savings will increase 
(decrease) in proportion to any increase (decrease) in the assessment of the building for city real estate tax purposes. 
The following table discloses how much of the new taxes we have generated is being relieved by the TIF and how much 
is being paid by ImmuCell: 

Twelve-Month   
Period Ended 

  Total New 

Taxes 
Generated by 
the Project 

Less:   
TIF Credit 

Net Amount 
Paid by   
ImmuCell 

June 30, 2018   
June 30, 2019   
June 30, 2020   
June 30, 2021   

$36,000   
$90,000   
$94,000   
$94,000   

$22,000   
$58,000   
$60,000   
$60,000   

$13,000   
$32,000   
$34,000   
$34,000   

Assessed Value 
$1.7M @ April 1, 2017 
$4.0M @ April 1, 2018 
$4.0M @ April 1, 2019 
$4.0M @ April 1, 2020 

Results of Operations   

Product Sales 

Total product sales during the year ended December 31, 2020 increased by 12%, or $1.6 million, to $15.3 

million from $13.7 million during the year ended December 31, 2019, with domestic sales increasing by 12% and 
international sales increasing by 11% in comparison to the year ended December 31, 2019. International sales 
aggregated 11% of total sales during both the years ended December 31, 2020 and 2019. The compound annual 
growth rate of our total product sales during the ten years ended December 31, 2020 was approximately 13%. The 
compound annual growth rate of our total product sales during the three years ended December 31, 2020 was 
approximately 18%. Sales achieved during 2020 were the equivalent of approximately 93% of the $16.5 million that 
we estimate to be our current annual production capacity. As of December 31, 2020, we had depleted our available 
finished goods inventory and had a backlog of orders worth approximately $1.8 million, compared to backlogs of 
approximately $130,000, $945,000, $1.4 million and $0 as of September 30, 2020, June 30, 2020, March 31, 2020 
and December 31, 2019, respectively. If we had been able to ship the backlog of orders before December 31, 2020, 
our total sales for the year ended December 31, 2020 would have reached approximately $17.2 million. This pro-
forma calculation indicates the current annual demand for our product and demonstrates the need for us to increase 
our annual production capacity over the current level of approximately $16.5 million (Project C, discussed above). 
While this is a very positive indication about the strong demand for our First Defense® product line, not being able 
to meet the needs of our customers presently could result in the loss of some customers that seek alternative scours 
management products during this period of short supply and may not resume purchasing our product when we have 
eliminated the backlog. We are missing some business during the peak season of 2021. As a result of this short 
supply, we anticipate that our sales during the three-month period ending March 31, 2021 will be approximately 
16% lower than the sales recorded during the three-month period ended March 31, 2020. The projected sales for the 
first quarter of 2021 represent the equivalent of approximately 100% of the $4.1 million that we estimate to be our 
current quarterly production capacity. As our product mix shifts in favor of Tri-Shield First Defense®, it has 
become more difficult to achieve or exceed this estimated production capacity. After our increased production 
capacity comes on-line during the second quarter of 2021, and assuming we sell and produce to plan, we expect 
sales for the year ending December 31, 2021 to be greater than sales recorded during the year ended December 31, 
2020. A precise estimation of the amount of the recovery from the first quarter sales drop to the anticipated year-
over-year sales increase is very difficult to make, given the uncertainties related to the impacts of new business 
opportunities missed due to COVID-related restrictions and customers lost (that may be or may not return at or 
above prior levels of purchasing) and other factors experienced during the period of order backlog. 

23 

 
 
 
 
 
 
 
ImmuCell Corporation 
Investments in the First Defense® product line have created positive results. Sales of the First Defense® 
product line increased by 14% during the year ended December 31, 2020 in comparison to the year ended December 
31, 2019, aggregating 98% and 97% of our total product sales during the years ended December 31, 2020 and 2019, 
respectively. Most of our growth is being realized through increased demand and a deliberate strategy to bias limited 
production capacity towards Tri-Shield® (the trivalent format of our product delivered via a gel tube), which 
provides broader protection to calves.   

Starting in the third quarter of 2016 and through most of 2017, we had sufficient available inventory and were 

shipping in accordance with the demand of our distributors. However, we quickly sold out of our initial launch 
quantities of Tri-Shield First Defense® soon after regulatory approval was obtained during the fourth quarter of 
2017. During most of 2018 and into the first half of 2019, we could only accept purchase orders from customers for 
Tri-Shield® to match available inventory, which required a careful allocation of product supply directly to certain 
end-users and veterinary clinics. Initially, production of this new product format did not keep pace with demand 
primarily because of our inability to produce enough of the new, complex rotavirus vaccine that is used to immunize 
our source cows. Work on production improvements in our vaccine laboratory throughout 2018 led to significant 
improvements in vaccine yield and process repeatability resolving this Tri-Shield® shortfall going into 2019. 
Allowing for the five to six month production cycle from the manufacture of our proprietary vaccine to the 
production of a finished dose, we were able to return to a mass market selling approach through distribution for Tri-
Shield® during the second half of 2019. We ended the year with no backlog of orders for the First Defense® product 
line as of December, 31 2019. Our current production output was not enough to meet increasing demand for the 
First Defense® product line during 2020, and, as noted above, we ended the year with a backlog of orders worth 
approximately $1.8 million as of December 31, 2020. We expect to fully realize the benefits of our expanded 
production capacity beginning during the second quarter of 2021. 

Valuation of the backlog is a non-GAAP estimate that is based on purchase orders on hand at the time that 
could not be met because of lack of available inventory. While we are confident that our customers would have 
accepted and paid for this product if it had been available to ship, we do allow customers to cancel orders, in whole 
or in part, to meet their current needs as time goes by. This is happening during the first quarter of 2021 and may 
continue to happen as we work to clear the backlog during the second quarter of 2021. Therefore, the measurement 
of the backlog amount is no longer a consistent indication of the amount of unmet demand for our product. As the 
increased production capacity comes online during the second quarter of 2021, we expect to fulfill the remaining 
backlog and meet ongoing strong demand. This would allow us to build inventory during the second half of 2021and 
return to a growth mode, as we prepare for peak season sales during the first quarter of 2022 without risk of backlog.   

We are gaining market share in the United States year after year with our Beyond Vaccination® strategy. Our 
share of the market (on a unit volume basis) of scour preventative products administered at the calf-level increased 
to approximately 41% during 2020 (from 36% during 2019, 34% during 2018 and 32% during 2017). Our share of 
the market of calves treated with products administered to calves and those administered to the dam prior to calving 
(adjusting for two doses of dam-level scour vaccines required for primary vaccination of first-calf-heifers) increased 
to approximately 13% during 2020 (from 11% during 2019, 10.3% during 2018 and 9.7% during 2017). We see the 
potential for future market share growth in the dairy market, and we have increased our focus on the beef market. 

Effective January 1, 2019, we implemented a 2% price increase for Dual-Force®. Effective February 1, 2020, 

we implemented a price increase of approximately 2% on the First Defense® product line (except for Tri-Shield® 
and the 90-dose bulk powder format) and CMT. Effective January 1, 2021, we increased our selling price of the 
First Defense® product line in the domestic market by approximately 1.6% to 3%, depending on product format, and 
we increased our selling price of CMT by almost 4%. 

Sales of products other than the First Defense® product line decreased by 44%, or $209,000, to $270,000 
during the year ended December 31, 2020 in comparison to the year ended December 31, 2019. Sales of these other 
products aggregated approximately 2% and 3% of our total product sales during the years ended December 31, 2020 
and 2019, respectively. We sell our own CMT (our second leading source of product sales during 2020 and our third 
leading source of product sales during 2019) which is used to detect somatic cell counts in milk. We acquired a 
private label product (our third leading source of product sales during 2020 and our second leading source of 
product sales during 2019) in connection with our January 2016 acquisition of certain gel formulation technology. 
We have made and sold bulk reagents for Isolate™ (our fourth leading source of product sales during 2019), which 
is a drinking water test that is sold by our former distributor in the United Kingdom. We made one final sale of this 

24 

 
ImmuCell Corporation 
product to this distributor worth $134,000 during the first quarter of 2019. Because this product was non-core to our 
strategic focus, we sold the underlying cell line assets and intellectual property to our former distributor during the 
third quarter of 2018 for $700,000. We have retained the rights to all animal health, diagnostic, feed and nutritional 
applications of this technology.   

The extent of the negative impact of the COVID-19 pandemic on the economics of our customers and on the 
demand for our products going forward is very difficult to assess. The Class III milk price (measured in dollars per 
100 pounds) averaged $18.16 during the year ended December 31, 2020, but this price has been extremely volatile 
during the pandemic. For example, the price increased by 102% from a low of $12.14 during May 2020 to a recent 
high of $24.54 during July, which is very close to an all-time record high of $24.60 during September 2014. 
Initially, stay at home orders disrupted the food service supply system as schools closed and restaurants were shut 
down. In response, producers were forced to reduce the supply of milk to the market by drying off cows early, 
culling cows from the herd and dumping milk, among other tactics. Market conditions are better now, but this 
volatility remains a concern, and there is no way to be confident that these recent high milk prices will be sustained. 
The $938,000 in funding that we received from the federal government through the Paycheck Protection Program 
(PPP) under the CARES Act helped us maintain full employment without furloughs or layoffs and continue 
executing our growth plans, even though we may see a future decline in sales and gross margin as a result of the 
pandemic. The PPP funding created some needed financial liquidity allowing us to move forward with our 
investments even though we did not achieve the level of sales anticipated in our 2020 budget. After making several 
inquiries into different laboratories, we were able to have our antibodies tested for effectiveness against COVID-19 
during the second quarter of 2020. While we understood that COVID-19 and bovine coronavirus are in different 
taxonomic groups, we wanted to investigate whether our antibodies could offer some cross-neutralization of 
COVID-19 in the laboratory testing. Unfortunately, the test results indicated, as expected, that our antibodies offered 
no viral neutralization activity, meaning they would be ineffective against COVID-19. 

Gross Margin 

Changes in our gross margin (product sales less costs of goods sold) are summarized in the following table for 

the respective periods (in thousands, except for percentages): 

Gross margin 
Percent of product sales 

During the Years Ended December 31, 

Increase (Decrease) 

2020 

2019 

Amount 

% 

$6,863   
45%   

$6,740   
49%   

$123   
(4%)   

2% 
(9%) 

The gross margin as a percentage of product sales was 45%, 49%, 47% and 50% during the years ended 
December 31, 2020, 2019, 2018 and 2017, respectively. The gross margin as a percentage of sales during 2020 was 
lower than what we normally expect, but we did increase the gross margin dollars over prior year. The gross margin 
percentage for the legacy format (capsule) of the First Defense® product line was in excess of 50%, which was in 
line with prior years. The Tri-Shield® product format is more complex (i.e. three antibodies versus two antibodies 
for Dual-Force®) and both the bivalent and trivalent gel product formats are more expensive to produce than the 
bolus format. These new formats are creating sales growth for us, and we are focused on increasing total gross 
margin dollars, even if that is accomplished with a lower gross margin as a percentage of sales. Throughout 2020, 
we invested significantly in equipment, infrastructure and operating expenses to increase our annual production 
capacity from approximately $16.5 million to approximately $23 million, but we were not able to spread the full 
benefit of those costs over higher production output because the increased capacity will not be on-line until the 
second quarter of 2021. We have estimated that this impact drove our gross margin down by a little more than a 
percentage point. A number of other factors contribute to the variability in our costs, resulting in some fluctuations 
in gross margin percentages from quarter to quarter and from year to year. Like most U.S. manufacturers, we have 
also been experiencing increases in the cost of labor and raw materials. We also invest to sustain compliance with 
current Good Manufacturing Practices (cGMP) in our production processes. Increasing production can be more 
expensive in the initial stages. To achieve our inventory production growth objectives, we are acquiring more raw 
material (colostrum) from many more cows at many new farms. As is the case with any vaccine program, animals 
respond less effectively to their first exposure to a new vaccine and then the effectiveness of their immune response 
improves in response to subsequent immunizations. As a result, during this expansion phase, similar quantities of 
colostrum are yielding fewer doses of finished product, which results in higher costs of goods sold. Additionally, the 

25 

 
 
 
 
 
 
 
 
 
 
   
   
   
 
ImmuCell Corporation 
biological yields from our raw material are always variable, which impacts our costs of goods sold in a similar way. 
Just as our customers’ cows respond differently to commercial dam-level vaccines, depending on time of year and 
immune competency, our source cows have similar biological variances in response to our proprietary vaccines. The 
value of our First Defense® product line is that we compensate for the variability in a cow’s immune response by 
standardizing each dose of finished product. This ensures that every calf is equally protected, which is something 
that dam-level commercial scours vaccines cannot offer. We continue to work on processing and yield 
improvements and other opportunities to reduce costs, while enhancing process knowledge and robustness. Over 
time, we have been able to reduce the impact of cost increases by implementing yield improvements. As we evaluate 
our product costs and selling price, it is one of our goals to continue to achieve a gross margin (before related 
depreciation and amortization expenses) as a percentage of total sales of almost 50%.   

Product Development Expenses 

Overview: In accordance with our budget and plans, during the year ended December 31, 2020, product 
development expenses increased by 18%, or $667,000, to $4.4 million in comparison to $3.7 million during the year 
ended December 31, 2019. Product development expenses aggregated 28% and 27% of product sales during the 
years ended December 31, 2020 and 2019, respectively. It is important to note that these figures include 
approximately $1.6 million of non-cash depreciation and stock-based compensation expenses during both the years 
ended December 31, 2020 and 2019. We do expect our product development expenses to decrease after Re-Tain™ 
is commercialized and most of the costs incurred to maintain and run our Drug Substance production facility 
become part of our costs of goods sold. 

Expenses pertaining to Re-Tain™: The majority of our product development spending has been focused on the 

development of Re-Tain™, our purified Nisin treatment for subclinical mastitis in lactating dairy cows. Approval 
by the Center for Veterinary Medicine, U.S. Food and Drug Administration (FDA) of the New Animal Drug 
Application (NADA) for Re-Tain™ is required before any sales of the product can be initiated. The NADA is 
comprised of five principal Technical Sections and one administrative submission that are subject to phased review 
by the FDA. By statute, each Technical Section submission is generally subject to a six-month review cycle by the 
FDA. Each Technical Section can be reviewed and approved separately. Upon review and assessment by the FDA 
that all requirements for a Technical Section have been met, the FDA may issue a Technical Section Complete 
Letter. The current status of our work on these submissions to the FDA is as follows: 

1)    Environmental Impact: During the third quarter of 2008, we received the Environmental Impact Technical 
Section Complete Letter from the FDA. 

2)    Target Animal Safety: During the second quarter of 2012, we received the Target Animal Safety Technical 
Section Complete Letter from the FDA. 

3)    Effectiveness: During the third quarter of 2012, we received the Effectiveness Technical Section Complete 
Letter from the FDA. The draft product label carries claims for the treatment of subclinical mastitis associated with 
Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis, and coagulase-negative staphylococci 
in lactating dairy cattle. In our pivotal effectiveness study, statistically significant cure rates were associated with a 
statistically significant reduction in milk somatic cell count, which is an important measure of milk quality. 

4)    Human Food Safety: During the third quarter of 2018, we received the Human Food Safety Technical Section 
Complete Letter from the FDA confirming, among other things, a zero milk discard period and a zero meat withhold 
period during and after treatment with our product.   

5)    Chemistry, Manufacturing and Controls (CMC): Having previously achieved the four different Technical 
Section Complete Letters from the FDA discussed above, approval of the CMC Technical Section is the fifth and 
final significant step required before Re-Tain™ product sales can be initiated in the United States. Implementing 
Nisin Drug Substance (the active pharmaceutical ingredient) production at our commercial facility, which is a 
required component of the CMC Technical Section, has been the most expensive and lengthy part of this project. 
We previously entered into an agreement with a multi-national pharmaceutical ingredient manufacturer for our 
commercial-scale supplies of Nisin. However, we determined during 2014 that the agreement did not offer us the 
most advantageous supply arrangement in terms of either cost or long-term dependability. We presented this product 
development opportunity to a variety of large and small animal health companies. While such a corporate 
partnership could have provided access to a much larger sales and marketing team and allowed us to avoid the large 
investment in a commercial-scale production facility, we concluded that a partner would have taken an unduly large 

26 

 
ImmuCell Corporation 
share of the gross margin from all future product sales of Re-Tain™. The regulatory and marketing feedback about 
the prospects for this product that we received from prospective partners, following their due diligence, was positive. 
During the third quarter of 2014, we completed an investment in facility modifications and processing equipment 
necessary to produce the Nisin Drug Substance at small-scale at our 56 Evergreen Drive facility. This small-scale 
facility was used to: i) expand our process knowledge and controls, ii) establish operating ranges for critical process 
parameters, iii) conduct product stability studies, iv) optimize process yields and v) verify the cost of production. 
We believe these efforts have reduced the risks associated with our investment in the commercial-scale Drug 
Substance production facility. Having raised equity during 2016 and 2017, we were able to move away from these 
earlier strategies and assume control over the commercial-scale manufacturing process in our own facility. During 
the fourth quarter of 2015, we acquired land near our existing Portland facility for the construction of a new 
commercial-scale Drug Substance production facility. We commenced construction of this facility during the third 
quarter of 2016 and completed construction during the fourth quarter of 2017. Equipment installation and 
qualification was initiated during the third quarter of 2017 and completed during the third quarter of 2018. Total 
construction and equipment costs aggregated approximately $20.8 million. 

We have always believed that the fastest route to FDA approval and market launch is with the services of 

Norbrook Laboratories Limited of Newry, Northern Ireland (an FDA-approved Drug Product manufacturer), 
benefiting from their demonstrated expertise in aseptic filling. From 2010 to 2015, we had been a party to an 
exclusive product development and contract manufacturing agreement with Norbrook covering the Drug Product 
formulation, aseptic filling and final packaging services. Norbrook provided services to us under this contract 
throughout the FDA process for use in all of our pivotal studies. During the fourth quarter of 2015, this agreement 
was amended and restated to create a Product Development and Contract Manufacture Agreement (the 2015 
Agreement) to, among other things, extend the term of the agreement to January 1, 2024 provided that FDA 
approval for commercial sales of Re-Tain™ in the United States was obtained by December 19, 2019. It had been 
our expectation that we would have these services available through both the remainder of the development process 
to FDA approval and for approximately the first four years of commercial sales of Re-Tain™. Due to unexpected 
difficulties and delays encountered by Norbrook and the statutory FDA timeline for processing CMC Technical 
Sections, this December 2019 product approval target date was not achieved. During the third quarter of 2019, we 
entered into a Development Services and Commercial Supply Agreement (the 2019 Agreement) with Norbrook. The 
2019 Agreement replaced and superseded the 2015 Agreement in its entirety. Under the 2019 Agreement, Norbrook 
provided the formulation, aseptic filling and final packaging services as required in order for us to submit the CMC 
Technical Section to the FDA. The 2019 Agreement also provides for Norbrook to perform formulation, aseptic 
filling and final packaging services in accordance with purchase orders that we submit from time to time for 
inventory build and subsequent product sales worth up to approximately $7 million for orders placed through 
December 31, 2021 with deliveries extending into the first half of 2022. We believe that the 2019 Agreement will 
enable us to commence sales of Re-Tain™ without delay upon receipt of the anticipated FDA approval. We intend 
to use the supply provided under the 2019 Agreement to bridge until our own formulation and aseptic filling 
capacity is available. We are in discussions with Norbrook about amending the 2019 agreement to cover some level 
of orders placed during 2022 in order to avoid potential interruptions in the supply of Re-Tain™ following receipt 
of FDA approval and commencement of commercial sales.   

Our potential alternative options for the formulation and aseptic filling services are narrowed considerably 

because our product cannot be formulated or filled in a facility that also processes traditional antibiotics (i.e., beta 
lactams). Consequently, we have decided to perform these services internally. Through a public offering of our 
common stock in March of 2019, we received net proceeds of approximately $8.3 million, of which approximately 
$4 million has been allocated to the equipping and commencement of operations of our own Drug Product 
formulation and aseptic filling facility. Based on current construction plans and equipment ordering and installation 
timelines, we expect our facility to be operational during the first half of 2022. We anticipate FDA approval of this 
facility during the fourth quarter of 2022 or the second quarter of 2023. This new facility will be subject to FDA 
inspection and approval and will have enough formulation and aseptic filling capacity to exceed the expected 
production capacity of our Drug Substance facility, which is at least $10 million in annual sales. This production 
capacity estimate is based on our assumptions as to product pricing and does not yet reflect inventory build 
strategies in advance of product approval or ongoing yield improvement initiatives. Establishing our own Drug 
Product formulation and aseptic filling capability provides us with the longer-term advantage of controlling the 
manufacturing process for Re-Tain™ in one facility, thereby potentially reducing our manufacturing costs and 
eliminating international cold chain shipping logistics and costs. The Drug Product formulation and aseptic filling 

27 

 
ImmuCell Corporation 

operation will be located in existing facility space that we had intended to utilize to double our Drug Substance 
production capacity if warranted by sales volumes following market launch. As a result, we would need to explore 
alternative strategies (in parallel with ongoing Drug Substance yield improvement initiatives) to expand our Drug 
Substance production capacity in order to meet anticipated long-term Re-Tain™ sales demand. This integrated 
manufacturing capability for Re‐Tain™ will substantially reduce our dependence on third parties. Upon completion 
of our formulation and aseptic filling facility, the only significant third‐party input for Re‐Tain™ will be the Drug 
Product syringes. It is anticipated that Hubert De Backer of Belgium (HDB) will supply these syringes in 
accordance with purchase orders that we submit. HDB is a syringe supplier for many of the largest participants in 
the human and veterinary medical industries, and with whom Norbrook presently works. Based on HDB’s 
performance history and reputation in the industry, we are confident that HDB will be a dependable supplier of 
syringes in the quantity and of the quality needed for Re‐Tain™. We have not yet determined if we will perform the 
final packaging services in-house or contract to have those services performed by a qualified third party in the 
United States.   

The Chemistry, Manufacturing and Controls Technical Section is very complex and comprehensive. Under the 

FDA’s phased submission process, the first-phased submission covers the Nisin Drug Substance (DS), and the 
second-phased submission covers the DS and the Re-Tain™ Drug Product (formulated DS filled in a syringe, or 
DP). This process allows a sponsor to respond to identified queries and/or deficiencies from the first-phased DS 
submission at the time of the second-phased DS and DP submission, which includes detailed information about the 
manufacturing process and controls for the DP. We made our first-phased DS submission during the first quarter of 
2019. This submission included data from the DS Registration Batches produced at commercial scale in our new DS 
manufacturing facility. As part of the phased submission process, the FDA issued a Technical Section Incomplete 
Letter with regard to this first-phased DS submission during the third quarter of 2019 with various requests and 
queries in addition to referring to the fact that the second-phased DS and DP submission had yet to be submitted. We 
expected this response. In addition to responding to comments raised by the FDA regarding the first-phased DS 
submission, one of the key components of the second-phased DS and DP submission is demonstrating stability of 
the product over time using the commercial process and the commercial syringe in its final packaged form. We 
made the first submission of the second-phased DS and DP submission during the first quarter of 2021. A response 
from the FDA to this submission is anticipated during the third quarter of 2021 (six months after the submission 
date). This type of complex submission is often subject to two reviews by the FDA. We do not expect three 
submissions. If the FDA responds with a Technical Section Incomplete Letter, we would need time to prepare our 
response and then make one or more additional submissions (each subject to its own six-month review period) until 
the FDA is satisfied that we have adequately responded to their queries before the final 60-day administrative review 
period (the last step in the regulatory approval process) can be initiated. Assuming two reviews by the FDA, product 
approval would not be expected before the second quarter of 2022. Given the risk reduction we achieved by making 
the first-phased DS submission and by working with an FDA-approved DP manufacturer, it is possible that we could 
receive a first-time approval of the DS and DP submission during the third quarter of 2021, which could lead to 
FDA approval of our NADA during the fourth quarter of 2021. While being prudent with how much cash we invest 
into inventory that would have short expiry dating if market launch is not until the second quarter of 2022, we do 
intend to build some inventory during 2021 in preparation for the potential of an initial, limited market launch 
during the fourth quarter of 2021. We plan to continue to build more inventory during 2021 and 2022 to bridge the 
transition between DP supply from our contractor to our own in-house services. Our next objective is to prove the 
value of this new product concept as we develop a new product category. The road to commercial success for a new 
FDA-regulated product can be a long one for a small-cap company.   

Successful FDA inspections of the manufacturing facilities must also be achieved before the NADA can be 
approved. During the third quarter of 2019, the FDA conducted a pre-approval inspection of our DS facility. This 
resulted in the issuance of certain deficiencies as identified on the FDA’s Form 483. We submitted responses and 
data summaries in a phased manner over the fourth quarter of 2019 and first quarter of 2020. We anticipate a follow-
up inspection by the FDA during the first half of 2021 to confirm the corrective actions that we have implemented. 
This inspection process has been managed without significant cost or impact on the timeline to product approval.   

Other product development initiatives: Our second most important product development initiative (in terms of 

dollars invested and, we believe, potential market impact) has been focused on other improvements, extensions or 
additions to our First Defense® product line. During the second quarter of 2009, we entered into an exclusive 
license with the Baylor College of Medicine covering the animal health rights to the underlying rotavirus vaccine 

28 

 
ImmuCell Corporation 

technology that we use to generate the specific antibodies. This perpetual license (if not terminated for cause) was 
subject to royalty payments through December 31, 2019. We achieved product license approval and initiated market 
launch of this product, Tri-Shield First Defense®, during the fourth quarter of 2017. During the third quarter of 
2018, we obtained approval from the Canadian Food Inspection Agency (CFIA) to sell Tri-Shield® in Canada. We 
initiated sales in Canada during the fourth quarter of 2019. We achieved USDA approval of our bivalent gel tube 
formulation (formerly marketed as First Defense Technology®) during the fourth quarter of 2018 and have re-
branded this product format as Dual-Force First Defense®. During the first quarter of 2019, we obtained CFIA 
approval to sell the gel tube format of Dual-Force® in Canada and have initiated commercial sales there. We are 
currently working to establish USDA claims for our bivalent bulk powder formulation of First Defense 
Technology®. We are also investing in additional studies to further support the First Defense® product line in the 
market. At the same time, we are working to expand our product development pipeline of bacteriocins that can be 
used as alternatives to traditional antibiotics. Subject to the availability of resources, we intend to begin new 
development projects that are aligned with our core competencies and market focus. We also remain interested in 
acquiring, on suitable terms, other new products and technologies that fit with our sales focus on the dairy and beef 
industries. 

Sales and Marketing Expenses 

During the year ended December 31, 2020, sales and marketing expenses decreased by approximately 6%, or 

$150,000, to $2.2 million in comparison to $2.3 million during the year ended December 31, 2019, amounting to 
14% and 17% of product sales during the years ended December 31, 2020 and 2019, respectively. We were able to 
reduce selling expenses during 2020, but we do expect these expenses to increase to approximately 20% of total 
product sales during 2021 as we begin to invest in the anticipated market launch of Re-Tain™ before any new sales 
are realized and as in-person marketing opportunities, such as industry events, return when COVID restrictions are 
eased. Our budgetary guideline for 2022 and after is to keep these expenses under 20% of total sales. This ratio is 
expected to come down incrementally as sales grow. Our sales team has pivoted effectively to alternative selling 
strategies and methods during the COVID-19 pandemic to be successful at a time when most trade shows have been 
cancelled and travel and on-farm visitations have been limited. The reduced travel and trade show expenses and 
having two open sales positions (during part of the year) resulted in some cost savings. We continue to leverage the 
efforts of our small sales force by using animal health distributors. Sales and marketing expenses included 
approximately $91,000 and $109,000 of non-cash depreciation and stock-based compensation expenses during the 
years ended December 31, 2020 and 2019, respectively.   

Administrative Expenses 

During the year ended December 31, 2020, administrative expenses increased by approximately 2%, or 
$33,000, to just over $1.7 million in comparison to just under $1.7 million during the year ended December 31, 2019. 
Administrative expenses included approximately $156,000 and $208,000 of non-cash depreciation and stock-based 
compensation expenses during the years ended December 31, 2020 and 2019, respectively. Expenses during the first 
quarter of 2020 included fees paid to predecessor auditors, a new employee hiring fee and some extra legal work. We 
strive to be efficient with these expenses while funding costs associated with complying with the Sarbanes-Oxley Act 
of 2002 and all the legal, audit and other costs associated with being a publicly-held company. Prior to 2014, we had 
limited our investment in investor relations spending. Beginning in the second quarter of 2014, we initiated an 
investment in a more active investor relations program. Given travel restrictions related to the COVID-19 pandemic, 
this initiative has pivoted to a virtual meeting format, which is less expensive. At the same time, we continue to 
provide full disclosure of the status of our business and financial condition in three quarterly reports and one annual 
report each year, as well as in Current Reports on Form 8-K when legally required or deemed appropriate by 
management. These efforts may have helped us access the capital markets to fund our growth objectives. Additional 
information about us is available in our annual Proxy Statement. All of these reports are filed with the SEC and are 
available on-line or upon request to the Company.   

Net Operating Loss 

During the year ended December 31, 2020, our net operating loss increased by 45%, or $426,000, to $1.4 

million in comparison to $954,000 during the year ended December 31, 2019. An increase of $667,000 in product 
development expenses (that was in line with our budgeted plans) was the largest contributor to this increase in our 
net operating loss. 

29 

 
Other (Income) Expenses, net   

ImmuCell Corporation 

During the year ended December 31, 2020 other (income), net, aggregated ($348,000), which was in contrast 

to other expenses, net, of $314,000 during the year ended December 31, 2019. The primary cause of this change 
from expense to income was the recognition of $938,000 in debt forgiveness as other income, net, during the fourth 
quarter of 2020 from our Paycheck Protection Program (PPP) loan from the federal government received under the 
CARES Act. The $938,000 in PPP funding that we received during the second quarter of 2020 provided increased 
financial flexibility, strengthening our balance sheet with more liquidity and cash on hand, thereby enabling us to 
remain focused on our critical growth objectives and investments. The PPP funding has also given us the confidence 
to advance our $4 million investment to bring the formulation and aseptic filling services for Re-Tain™ Drug 
Product in-house. This support has helped us avoid layoffs and furloughs thus far. Interest expense decreased to 
$413,000 during the year ended December 31, 2020 from $432,000 during the year ended December 31, 2019. Non-
cash amortization of debt issuance costs was $103,000 and $17,000 during the years ended December 31, 2020 and 
2019, respectively. During the year ended December 31, 2020, amortization of debt issuance costs also included the 
write-off of $95,000 in debt issuance costs associated with our bank debt refinancing during the first quarter of 
2020. Excluding the amortization and write-off of debt issuance costs, cash-based interest expense incurred during 
the year ended December 31, 2020 decreased to $310,000 from $415,000 during the year ended December 31, 2019. 
Other income, net, during the year ended December 31, 2020 included an expense of $165,000 to terminate our 
interest rate swap agreements associated with our bank debt refinancing during the first quarter of 2020, which is 
recorded as a component of interest expense. Given the debt refinancing to fixed rate loans during the first quarter of 
2020 and the refinancing we closed during the fourth quarter of 2020, we anticipate that our interest expense will be 
approximately $317,000, $287,000 and $258,000 during the years ending December 31, 2021, 2022 and 2023, 
respectively. Interest income was $27,000 and $121,000 during the years ended December 31, 2020 and 2019, 
respectively. Less interest income was earned during 2020 largely because we had less cash and short-term 
investments on hand and a lower interest rate environment. The results included a non-cash write-off of fixed assets 
in the amount of $39,000 during the year ended December 31, 2020 in comparison to $2,000 during 2019.   

Loss Before Income Taxes   

During the year ended December 31, 2020, our loss before income taxes decreased by 19%, or $235,000, to $1 
million, in comparison to a loss before income taxes of $1.3 million during the year ended December 31, 2019. The 
largest contributor to this improvement was the $938,000 in other income recognized from the forgiveness of our 
Paycheck Protection Program loan from the federal government during the fourth quarter of 2020.   

Income Taxes and Net Loss   

During the years ended December 31, 2020 and 2019, we recorded income tax (benefit) expense of ($10,000) 

and $28,000, respectively. Our income tax (benefit) expense amounted to (1%) and 2% of our loss before income 
taxes during the years ended December 31, 2020 and 2019, respectively. Our net loss of $1 million, or $0.14 per 
share, during the year ended December 31, 2020 was in comparison to a net loss of $1.3 million, or $0.19 per share, 
during the year ended December 31, 2019.   

For tax return purposes only, our depreciation expense for the Nisin Drug Substance production facility and 

equipment was approximately $464,000, $639,000, $9.2 million and $1.5 million for the years ended December 31, 
2020, 2019, 2018 and 2017, respectively. The significant increase during 2018 was largely related to accelerated 
depreciation allowed for tax purposes. As of December 31, 2020, our federal net operating loss carryforward was 
approximately $14.6 million, which will be available to offset future taxable income. On December 22, 2017, the 
Tax Cuts and Jobs Act was signed into law. This legislation makes significant changes in the U.S. tax laws, 
including a reduction in the corporate tax rates, changes to net operating loss carryforwards and carrybacks, and a 
repeal of the corporate alternative minimum tax. The legislation reduced the U.S. corporate tax rate from 34% to 
21%. Our income tax rate differs from this standard tax rate primarily because we are currently providing for a full 
valuation allowance against our deferred tax assets. While we are recording this full valuation allowance and 
therefore not recognizing a benefit on our tax losses, our income tax expense is largely comprised of the tax effect of 
the interest rate swap agreements that we terminated during the first quarter of 2020.   

In addition to the above results from our Statements of Operations, we believe it is important to consider our 
Statements of Cash Flows in the accompanying audited financial statements to assess the cash generating ability of 
our operations.   

30 

 
Critical Accounting Policies 

ImmuCell Corporation 

The financial statements are presented on the basis of accounting principles that are generally accepted in the 

United States. All professional accounting standards that were effective and applicable to us as of December 31, 
2020 have been taken into consideration in preparing the financial statements. The preparation of financial 
statements requires that we make estimates and judgments that affect the reported amounts of assets, liabilities, 
revenues and expenses, and related disclosure of contingent assets and liabilities. On an on-going basis, we evaluate 
our estimates, including those related to revenue recognition, income taxes, contingencies and the useful lives and 
carrying values of intangible and long lived assets. We base our estimates on historical experience and on various 
other assumptions that we believe are reasonable under the circumstances, the results of which form the basis for 
making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. 
Actual results may differ from these estimates under different assumptions or conditions. We have chosen to 
highlight certain policies that we consider critical to the operations of our business and understanding our financial 
statements. 

We sell products that provide Immediate Immunity™ to newborn dairy and beef cattle. We recognize revenue 
in accordance with the five step model in ASC 606.  These include i) identification of the contract with the customer, ii) 
identification of the performance obligations in the contract, iii) determination of the transaction price, iv) allocation 
of the transaction price to the separate performance obligations in the contract and v) recognition of revenue associ-
ated with performance obligations as they are satisfied. We recognize revenue at the time of shipment (including to 
distributors) for substantially all products, as title and risk of loss pass to the customer on delivery to the common car-
rier after concluding that collectability is reasonably assured. We do not bill for or collect sales tax because our sales 
are generally made to distributors and thus our sales to them are not subject to sales tax. We generally have experi-
enced an immaterial amount of product returns. 

Inventory includes raw materials, work-in-process and finished goods and is recorded at the lower of cost, on the 
first-in, first-out method, or net realizable value (determined as the estimated selling price in the normal course of busi-
ness, less reasonably predictable costs of completion, disposal and transportation). Work-in-process and finished goods 
inventories include materials, labor and manufacturing overhead. 

ITEM 7A — QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK 

We believe that neither inflation, interest rates nor currency exchange rates have had a significant effect on our 

revenues and expenses. However, future increases in inflation or interest rates or the value of the U.S. dollar could 
affect our customers and the demand for our products. We hope to increase the level of our future sales of products 
outside the United States. The cost of our products to international customers could be affected by currency 
fluctuations. The decline of the U.S. dollar against other currencies could make our products less expensive to 
international customers. Conversely, a stronger U.S. dollar could make our products more costly for international 
customers. The devaluation of the dollar makes Euro-based purchases more expensive for us. We had outstanding 
bank debt totaling approximately $9.5 million as of December 31, 2020 that bears interest at the fixed rate of 3.5% 
per annum. Also, as of December 31, 2020, we had a subordinated loan from the State of Maine outstanding in the 
amount of $500,000 that bears no interest until the fourth quarter of 2022, at which time the note bears interest at a 
fixed rate of 5% per annum, unless it is repaid. See Note 10 to the accompanying audited financial statements for 
more details about our debt. 

ITEM 8 — FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA 

Our financial statements, together with the notes thereto and the reports of the independent registered public 

accounting firms thereon, are set forth on Pages F-1 through F-27 at the end of this report. The index to these 
financial statements is as follows: 

Report of Wipfli LLP, Independent Registered Public Accounting Firm 
Balance Sheets as of December 31, 2020 and 2019 
Statements of Operations during the years ended December 31, 2020 and 2019 
Statements of Comprehensive Loss during the years ended December 31, 2020 and 2019 
Statements of Stockholders’ Equity during the years ended December 31, 2019 and 2020 
Statements of Cash Flows during the years ended December 31, 2020 and 2019 
Notes to Audited Financial Statements 

F-1 to F-2 
F-3 
F-4 
F-4 
F-5 
F-6 to F-7 
F-8 to F-27 

31 

 
 
 
ImmuCell Corporation 

ITEM 9 — CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND 

FINANCIAL  DISCLOSURE 

On April 10, 2019, we informed RSM US LLP (RSM) that RSM had been dismissed as our independent 
registered public accounting firm due to our desire to work with a local firm and to obtain such services at a lower 
cost. This decision was authorized by our Audit Committee and ratified by our Board of Directors. 

There were no disagreements between us and RSM on any matter of accounting principles or practices, 

financial statement disclosure, or auditing scope or procedure, which disagreements, if not resolved to the 
satisfaction of RSM, would have caused RSM to make reference to the subject matter of the disagreements in either 
of RSM’s reports on our financial statements for the years ended December 31, 2018 or 2017. During the years 
ended December 31, 2018 and 2017, there were no reportable events (as defined in Item 304(a)(l)(v) of Regulation 
S-K), except for the material weakness in our internal control over financial reporting as disclosed in our Quarterly 
Reports on Forms 10-Q for the interim periods ended June 30, 2018 and September 30, 2018. None of such reports 
contained any adverse opinion or disclaimer or were qualified or modified as to uncertainty, audit scope or 
accounting principles. 

On April 12, 2019, we engaged Wipfli LLP (Wipfli) as our independent registered public accounting firm for 
the year ending December 31, 2019 beginning with a customary review of our financial statements as of and for the 
quarter ended March 31, 2019. On March 20, 2020, we engaged Wipfli as our independent registered public 
accounting firm for the year ending December 31, 2020. 

During the two most recent fiscal years and the interim periods preceding Wipfli’s engagement, and through 
the date of their engagements, neither we nor anyone on our behalf had previously consulted with Wipfli regarding 
either: (a) the application of accounting principles to a specified transaction, either completed or proposed; or the 
type of audit opinion that might be rendered on our financial statements, and neither a written report was provided 
nor oral advice was provided to us that Wipfli concluded was an important factor considered by us in reaching a 
decision as to the accounting, auditing or financial reporting issue or (b) any matter that was either the subject of a 
disagreement (as defined in paragraph 304 (a)(l)(iv) of Regulation S-K and the related instructions thereto) or a 
reportable event (as described in paragraph 304(a)(l)(v) of Regulation S-K). 

ITEM 9A — CONTROLS AND PROCEDURES 

Disclosure Controls and Procedures   

Our management, with the participation of the individual who serves as our principal executive and principal 

financial officer, evaluated the effectiveness of our disclosure controls and procedures as of December 31, 2020. 
Based on this evaluation, that officer concluded that our disclosure controls and procedures were effective as of that 
date. Disclosure controls and procedures are designed to ensure that information required to be disclosed by us in the 
reports that we file or submit under the Exchange Act is (i) recorded, processed, summarized and reported, within 
the time periods specified in the SEC’s rules and forms and (ii) accumulated and communicated to our management, 
including our principal executive and principal financial officer, as appropriate to allow timely decisions regarding 
required disclosures. 

Management’s Annual Report on Internal Control Over Financial Reporting 

The management of the Company is responsible for establishing and maintaining adequate internal control 

over financial reporting. The Company’s internal control over financial reporting is designed to provide reasonable 
assurance regarding the reliability of financial reporting and the preparation of financial statements for external 
purposes in accordance with generally accepted accounting principles. We conducted an evaluation of the 
effectiveness of the internal controls over financial reporting based on the framework in Internal Control - Integrated 
Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission. This evaluation 
included a review of the documentation of controls, evaluation of the design effectiveness of controls, testing the 
operating effectiveness of the controls and a conclusion on this evaluation. Because of its inherent limitations, 
internal control over financial reporting may not prevent or detect misstatements. Therefore, even those systems 
determined to be effective can provide only reasonable assurance with respect to financial statement preparation and 
presentation. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that 
controls may become inadequate because of changes in conditions, or that the degree of compliance with the 

32 

 
ImmuCell Corporation 

policies or procedures may deteriorate. Management assesses the effectiveness of the Company’s internal control 
over financial reporting at the end of each quarter. Based on management’s assessment, we believe that our internal 
control over financial reporting was effective as of December 31, 2020. This Annual Report does not include an 
attestation report of the Company’s independent registered public accounting firm regarding internal control over 
financial reporting. Management’s internal control report was not subject to attestation by the Company’s 
independent registered public accounting firm pursuant to rules of the Securities and Exchange Commission that 
permit the Company to provide only management’s report. 

Changes in Internal Controls over Financial Reporting   

The individual who serves as our principal executive and principal financial officer periodically evaluates any 

change in internal control over financial reporting which has occurred during the prior fiscal quarter. We have 
concluded that there was no change in our internal control over financial reporting that occurred during the quarter 
or year ended December 31, 2020 that has materially affected, or is reasonably likely to materially affect, our 
internal control over financial reporting. 

ITEM 9B — OTHER INFORMATION 

None 

PART III 

ITEM 10 — DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE 

Executive Officers of the Company 

Our executive officers as of March 19, 2021 were as follows: 

MICHAEL F. BRIGHAM (Age: 60, Officer since 1991, Director since 1999) was appointed to serve as 
President and Chief Executive Officer in February 2000, while maintaining the titles of Treasurer and Secretary, and 
was appointed to serve as a Director of the Company in March 1999. He previously had been elected Vice President 
of the Company in December 1998 and had served as Chief Financial Officer since October 1991. He has served as 
Secretary since December 1995 and as Treasurer since October 1991. Prior to that, he served as Director of Finance 
and Administration since originally joining the Company in September 1989. Mr. Brigham served as a member of 
the Board of Directors of the United Way of York County from 2012 to 2019, serving as its Treasurer until June 
2016 and as Chair of the Board of Directors for one year and as a member of its Executive Committee. Mr. Brigham 
served as the Treasurer of the Board of Trustees of the Kennebunk Free Library from 2005 to 2011. He re-joined the 
Finance Committee of the library in 2012. Prior to joining the Company, he was employed as an audit manager for 
the public accounting firm of Ernst & Young. Mr. Brigham earned his Masters in Business Administration from 
New York University in 1989 and a Bachelor of Arts degree (with a double major in Economics and Spanish) from 
Trinity College in Hartford, Connecticut in 1983. 

BOBBI JO BROCKMANN (Age: 44, Officer since February 2015, Director since January 2018) served as a 

Director of the Company from March 2017 to September 2017 and from January 2018 to the present. She was 
promoted to Vice President of Sales and Marketing in February 2015. She joined the Company as Director of Sales 
and Marketing in January 2010. Prior to that, she had been employed as Director of Sales since May 2008 and Sales 
Manager from February 2004 to April 2008 at APC, Inc. of Ankeny, Iowa, a developer and marketer of functional 
protein products for animal health and nutrition. Prior to that, she held other sales and marketing positions at 
APC, W & G Marketing Company, Inc. of Ames, Iowa, The Council for Agricultural Science and Technology of 
Ames, Iowa and Meyocks Group Advertising of West Des Moines, Iowa after graduating from Iowa State 
University. 

JOSEPH H. CRABB, Ph.D. (Age: 66, Officer since 1996) was elected Vice President of the Company in 
December 1998, while maintaining the title of Chief Scientific Officer. He has served as Chief Scientific Officer 
since September 1998. Prior to that, he served as Vice President of Research and Development since March 1996. 
Prior to that, he served as Director of Research and Development and Senior Scientist since originally joining the 
Company in November 1988. He served as a Director of the Company from March 2001 (having previously served 
in that capacity from March 1999 until February 2000) until September 2017. He served as Chair of the Board of 

33 

 
ImmuCell Corporation 

Directors from June 2009 to February 2013. Concurrent with his employment, he has served on national study 
sections and advisory panels, served as a peer reviewer, and held several adjunct faculty positions. Prior to joining 
the Company in 1988, Dr. Crabb earned his Ph.D. in Biochemistry from Dartmouth Medical School and completed 
postdoctoral studies in microbial pathogenesis at Harvard Medical School, where he also served on the faculty. 

ELIZABETH L. WILLIAMS (Age: 65, Officer since April 2016) joined the Company in April 2016 as Vice 

President of Manufacturing Operations. Previously, she led the U.S. Region for Zoetis as Vice President, Global 
Manufacturing and Supply. Prior to that, she held multiple Site Leader positions at Pfizer Animal Health facilities in 
Lincoln, Nebraska (2008-2011), Conshohocken, Pennsylvania (2006-2008) and Lee’s Summit, Missouri (2003-
2006). She led the manufacturing organization (1999-2003) and the Process and Product Development group (1995-
1999), achieving registration, approval and successful scale-up of five new products at the Lee’s Summit facility. 
She earned her Masters of Business Administration from Rockhurst University in Kansas City, Missouri and her 
Bachelor’s degree in Biology from the University of Missouri. 

Information with respect to our directors is incorporated herein by reference to the section of our 2021 Proxy 

Statement titled “Election of the Board of Directors”, which we intend to file with the Securities and Exchange 
Commission within 120 days after December 31, 2020. There is no family relationship between any director, 
executive officer, or person nominated or chosen by the Company to become a director or executive officer. 

ITEM 11 — EXECUTIVE COMPENSATION 

Information regarding compensation paid to our executive officers is incorporated herein by reference to the 

section of our 2021 Proxy Statement titled “Executive Officer Compensation”, which we intend to file with the 
Securities and Exchange Commission within 120 days after December 31, 2020. 

34 

 
 
 
ImmuCell Corporation 
ITEM 12 — SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND 

RELATED STOCKHOLDER MATTERS 

Information regarding ownership of our common stock by certain owners and management is incorporated 
herein by reference to the section of our 2021 Proxy Statement titled “Security Ownership of Certain Beneficial 
Owners and Management and Related Stockholder Matters”, which we intend to file with the Securities and 
Exchange Commission within 120 days after December 31, 2020. 

ITEM 13 — CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS AND DIRECTOR 

INDEPENDENCE 

Information regarding certain relationships and related transactions and director independence is incorporated 

herein by reference to the section of our 2021 Proxy Statement titled “Certain Relationships and Related 
Transactions and Director Independence”, which we intend to file with the Securities and Exchange Commission 
within 120 days after December 31, 2020. 

ITEM 14 — PRINCIPAL ACCOUNTING FEES AND SERVICES 

Information regarding our principal accounting fees and services is incorporated by reference to the section of 

our 2021 Proxy Statement titled “Principal Accounting Fees and Services”, which we intend to file with the 
Securities and Exchange Commission within 120 days after December 31, 2020. 

35 

 
 
 
ImmuCell Corporation 
PART IV 

ITEM 15 — EXHIBITS AND FINANCIAL STATEMENT SCHEDULES 

3.1 

3.2 

3.3 

3.4 

3.5 

3.6 

3.7 

4.1 

4.1A 

4.1B 

4.1C 

4.1D 

4.1E 

4.1F 

4.2* 

Certificate of Incorporation of the Company (incorporated by reference to Exhibit 3.1 of the Company’s 
1987 Registration Statement No. 33-12722 on Form S-1 as filed with the Commission). 
Certificate of Amendment to the Company’s Certificate of Incorporation effective July 23, 1990 
(incorporated by reference to Exhibit 3.2 of the Company’s Annual Report on Form 10-K for the year 
ended December 31, 2008). 
Certificate of Amendment to the Company’s Certificate of Incorporation effective August 24, 1992 
(incorporated by reference to Exhibit 3.3 of the Company’s Annual Report on Form 10-K for the year 
ended December 31, 2008). 
Certificate of Amendment to the Company’s Certificate of Incorporation effective June 16, 2016 
(incorporated by reference to Exhibit 3.1 of the Company’s Amended Current Report on Form 8-K/A 
filed on June 16, 2016). 
Certificate of Amendment to the Company’s Certificate of Incorporation effective June 18, 2018 
(incorporated by reference to Exhibit 3.1 of the Company’s Current Report on Form 8-K filed on June 18, 
2018). 
Certificate of Amendment to the Company’s Certificate of Incorporation effective June 11, 2020 
(incorporated by reference to Exhibit 3.1 of the Company’s Current Report on Form 8-K filed on June 11, 
2020). 
Bylaws of the Company as amended (incorporated by reference to Exhibit 3.4 of the Company’s Annual 
Report on Form 10-K for the year ended December 31, 2008). 
Rights Agreement dated as of September 5, 1995, between the Company and American Stock Transfer 
and Trust Co., as Rights Agent, which includes as Exhibit A thereto the form of Right Certificate and as 
Exhibit B thereto the Summary of Rights to Purchase Common Stock (incorporated by reference to 
Exhibit 4.1 of the Company’s Quarterly Report on Form 10-Q for the quarterly period ended March 31, 
2009). 
First Amendment to Rights Agreement dated as of June 30, 2005 (incorporated by reference to 
Exhibit 4.1A of the Company’s Current Report on Form 8-K filed on July 5, 2005). 
Second Amendment to Rights Agreement dated as of June 30, 2008 (incorporated by reference to Exhibit 
4.1A of the Company’s Annual Report on Form 10-K for the year ended December 31, 2008). 
Third Amendment to Rights Agreement dated as of August 9, 2011 (incorporated by reference to Exhibit 
4.1 of the Company’s Quarterly Report on Form 10-Q for the three-month period ended June 30, 2011). 
Fourth Amendment to Rights Agreement dated as of June 16, 2014 (incorporated by reference to Exhibit 
4.1D of the Company’s Current Report on Form 8-K filed on June 17, 2014). 
Fifth Amendment to Rights Agreement dated as of April 15, 2015 (incorporated by reference to Exhibit 
4.1 of the Company’s Quarterly Report on Form 10-Q for the three-month period ended March 31, 2015). 
Sixth Amendment to Rights Agreement dated as of August 10, 2017 (incorporated by reference to Exhibit 
4.1 of the Company’s Quarterly Report on Form 10-Q for the three-month period ended June 30, 2017). 
Description of Securities Registered Under Section 12 of the Securities Exchange Act of 1934, as 
amended. 

10.1+  Form of Indemnification Agreement (updated) entered into with each of the Company’s Directors and 

10.2+ 

Officers (incorporated by reference to Exhibit 10.3A of the Company’s Annual Report on Form 10-KSB 
for the year ended December 31, 2006). 
2000 Stock Option and Incentive Plan of the Company (incorporated by reference to Exhibit 10.6 of the 
Company’s Annual Report on Form 10-K for the year ended December 31, 2008). 

10.3+  Form of Incentive Stock Agreement (incorporated by reference to Exhibit 10.7 of the Company’s Annual 

Report on Form 10-K for the year ended December 31, 2008). 

10.4+  Amendment to Employment Agreement between the Company and Michael F. Brigham dated March 26, 

2010 (incorporated by reference to Exhibit 10.6 of the Company’s Annual Report on Form 10-K for the 
year ended December 31, 2009). 

10.5+  Amendment to Employment Agreement between the Company and Joseph H. Crabb dated March 26, 

10.6+ 

2010 (incorporated by reference to Exhibit 10.7 of the Company’s Annual Report on Form 10-K for the 
year ended December 31, 2009). 
2010 Stock Option and Incentive Plan of the Company (incorporated by reference to Exhibit 10.6 of the 
Company’s Annual Report on Form 10-K for the year ended December 31, 2010). 

36 

 
 
ImmuCell Corporation 

10.7+  Form of Incentive Stock Option Agreement (incorporated by reference to Exhibit 10.7 of the Company’s 

10.8+ 

Annual Report on Form 10-K for the year ended December 31, 2010). 
2017 Stock Option and Incentive Plan of the Company (incorporated by reference to Exhibit 10.1 of the 
Company’s Quarterly Report on Form 10-Q for the three-month period ended June 30, 2017). 
10.9+  Form of Incentive Stock Option Agreement (incorporated by reference to Exhibit 10.9 of the Company’s 

Annual Report on Form 10-K for the year ended December 31, 2019). 

10.10+  Incentive Compensation Agreement dated March 21, 2019 between the Company and Elizabeth L. 

Williams (incorporated by reference to Exhibit 10.21 of the Company’s Annual Report on Form 10-K for 
the year ended December 31, 2019). 

10.11+  Severance Agreement between the Company and Michael F. Brigham dated as of March 25, 2020 

(incorporated by reference to Exhibit 10.20 of the Company’s Annual Report on Form 10-K for the year 
ended December 31, 2019). 

10.12+*   Amended and Restated Incentive Compensation Agreement between the Company and Bobbi Jo 

Brockmann dated as of March 29, 2021. 

10.13  Development Services and Commercial Supply Agreement between the Company and Norbrook 

Laboratories Limited dated as of September 5, 2019 (incorporated by reference to Exhibit 99.2 of the 
Company’s Current Report on Form 8-K filed on September 11, 2019). 

10.14  Termination Agreement between the Company and Nordson Corporation dated as of September 10, 2019 
(incorporated by reference to Exhibit 99.3 of the Company’s Current Report on Form 8-K filed on 
September 11, 2019). 
Indenture of Lease for Premises Located in Portland, Maine between the Company and TVP, LLC 
(incorporated by reference to Exhibit 99.2 of the Company’s Current Report on Form 8-K filed on 
September 17, 2019). 

10.15 

10.16  Term Note for $5,100,000 between the Company and Gorham Savings Bank dated March 11, 2020 

(incorporated by reference to Exhibit 99.2 of the Company’s Current Report on Form 8-K filed on March 
12, 2020). 

10.17  Term Note for $3,500,000 between the Company and Gorham Savings Bank dated March 11, 2020 

(incorporated by reference to Exhibit 99.3 of the Company’s Current Report on Form 8-K filed on March 
12, 2020). 

10.18  Loan Agreement for $5,100,000 between the Company and Gorham Savings Bank dated March 11, 2020 
(incorporated by reference to Exhibit 99.4 of the Company’s Current Report on Form 8-K filed on March 
12, 2020).   

10.19  Loan Agreement for $3,500,000 between the Company and Gorham Savings Bank dated March 11, 2020 
(incorporated by reference to Exhibit 99.5 of the Company’s Current Report on Form 8-K filed on March 
12, 2020. 

10.20  Line of Credit Agreement for up to $1,000,000 between the Company and Gorham Savings Bank dated 

10.21 

March 11, 2020 (incorporated by reference to Exhibit 99.6 of the Company’s Current report on Form 8-K 
filed on March 12, 2020). 
Promissory Note for $937,700 executed by the Company in favor of Gorham Savings Bank dated April 
13, 2020 (incorporated by reference to Exhibit 99.2 of the Company’s Current Report on Form 8-K filed 
on April 14, 2020). 

10.22  Note Purchase Agreement executed by the Company in favor of the Maine Technology Institute dated 

10.23 

June 12, 2020 (incorporated by reference to Exhibit 99.2 of the Company’s Current Report on Form 8-K 
filed on June 16, 2020). 
Subordinated Promissory Note for $500,000 executed by the Company in favor of the Maine Technology 
Institute dated June 12, 2020 (incorporated by reference to Exhibit 99.3 of the Company’s Current Report 
on Form 8-K filed on June 16, 2020). 

10.24  Term Note for $1,500,000 executed by the Company in favor of Gorham Savings Bank dated December 
15, 2020 (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed 
on December 17, 2020). 

10.25  Loan Agreement for $1,500,000 executed by the Company in favor of Gorham Savings Bank dated 

14 

December 15, 2020 (incorporated by reference to Exhibit 10.2 to the Company’s Current Report on Form 
8-K filed on December 17, 2020). 
Code of Business Conduct and Ethics (incorporated by reference to Exhibit 14 of the Company’s Current 
Report on Form 8-K filed on March 20, 2014). 

23.1*  Consent of Independent Registered Public Accounting Firm. 
31* 
32* 

Certifications Required by Rule 13a-14(a). 
Certification Required by Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act 

37 

 
 
of 2002. 

ImmuCell Corporation 

+ 
* 

Management contract or compensatory plan or arrangement. 
Filed herewith. 

101.INS  XBRL Instance Document. 
101.SCH  XBRL Taxonomy Extension Schema Document. 
101.CAL  XBRL Taxonomy Extension Calculation Linkbase Document. 
101.DEF  XBRL Taxonomy Extension Definition Linkbase Document. 
101.LAB XBRL Taxonomy Extension Label Linkbase Document. 
101.PRE  XBRL Taxonomy Extension Presentation Linkbase Document. 

38 

 
 
 
 
 
 
 
 
 
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM 

To the Stockholders and the Board of Directors of ImmuCell Corporation 

Opinion on the Financial Statements 

We have audited the accompanying balance sheets of ImmuCell Corporation (the “Company”) as of 

December 31, 2020 and 2019, and the related statements of operations, comprehensive loss, stockholders’ 
equity, and cash flows for each of the two years in the period ended December 31, 2020, and the related notes 
(collectively referred to as the “financial statements”). In our opinion, the financial statements present fairly, in 
all material respects, the financial position of the Company as of December 31, 2020 and 2019, and the results 
of its operations and its cash flows for each of the two years in the period ended December 31, 2020, in 
conformity with accounting principles generally accepted in the United States of America. 

Basis for Opinion 

These financial statements are the responsibility of the Company’s management. Our responsibility is to 
express an opinion on the Company’s financial statements based on our audits. We are a public accounting firm 
registered with the Public Company Accounting Oversight Board (United States) (“PCAOB”) and are required to 
be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable 
rules and regulations of the Securities and Exchange Commission and the PCAOB. 

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we 

plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of 
material misstatement, whether due to error or fraud. The Company is not required to have, nor were we engaged 
to perform, an audit of its internal control over financial reporting. As part of our audits, we are required to obtain 
an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on 
the effectiveness of the Company’s internal control over financial reporting. Accordingly, we express no such 
opinion. 

Our audits included performing procedures to assess the risks of material misstatement of the financial 

statements, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures 
included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements. 
Our audits also included evaluating the accounting principles used and significant estimates made by management, 
as well as evaluating the overall presentation of the financial statements. We believe that our audits provide a 
reasonable basis for our opinion. 

Critical Audit Matter 

The critical audit matter communicated below is a matter arising from the current period audit of the 
financial statements that was communicated or required to be communicated to the audit committee and that: 
(1) relates to accounts or disclosures that are material to the financial statements and (2) involved our especially 
challenging, subjective or complex judgments.    The communication of the critical audit matter does not alter 
in any way our opinion on the financial statements, taken as a whole, and we are not, by communicating the 
critical audit matter below, providing a separate opinion on the critical audit matter or on the accounts or 
disclosures to which it relates. 

Valuation of Inventory 

Description of the Matter 

At December 31, 2020, the Company’s inventory was $2,092,514. As discussed 
in Note 2 of the financial statements, inventory is recorded at the lower of cost, 
or net realizable value.   

F-1 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
How We Addressed the 
Matter In Our Audit 

Auditing management’s valuation of inventory is complex and highly 
judgmental because of the estimates and assumptions used by management to 
determine the cost accounting and because of the variability of the cost per dose 
due to fluctuations in the biological yield achieved. 

The primary procedures we performed to address this critical audit     
matter included the following. We obtained an understanding of the cost 
accounting developed by management and the related assumptions and estimates 
used. We tested the cost accounting by examining the underlying data used by 
the Company to prepare the cost accounting. We evaluated the effect of the 
variability of the cost per dose on the inventory value by comparing the 
biological yield to historical results and by performing a sensitivity analysis of 
the potential range in inventory value within a corridor of historical results based 
on minimum and maximum outcomes for the biological yield.   

We have served as the Company’s auditor since 2019. 

/s/ WIPFLI LLP 

South Portland, Maine 
March 30, 2021 

F-2 

 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ImmuCell Corporation 

BALANCE SHEETS 

As of December 31, 

2020 

2019 

ASSETS 

CURRENT ASSETS: 

Cash and cash equivalents 
Short-term investments 
Trade accounts receivable, net 
Inventory 
Prepaid expenses and other current assets 

Total current assets 

PROPERTY, PLANT AND EQUIPMENT, net 
OPERATING LEASE RIGHT-OF-USE ASSET   
GOODWILL 
INTANGIBLE ASSETS, net 
OTHER ASSETS 
TOTAL ASSETS 

LIABILITIES AND STOCKHOLDERS’ EQUITY 

CURRENT LIABILITIES: 

Current portion of debt obligations 
Current portion of operating lease liability 
Accounts payable and accrued expenses 

Total current liabilities 

LONG-TERM LIABILITIES: 

Debt obligations, net of current portion 
Operating lease liability, net of current portion 
Interest rate swaps 

Total long-term liabilities 

$6,949,937   
996,495   

$6,293,293 
2,480,753 
              1,796,801                       1,637,165 
              2,092,514                       2,518,256 
259,566 
13,189,033 

321,261   
12,157,008   

26,754,975   
1,220,361   
95,557   
95,520   
26,173   
$40,349,594   

25,265,738 
— 
95,557 
114,624 
26,884 
$38,691,836 

$760,337  
100,512  
1,350,227  
2,211,076   

8,737,149   
1,135,169  
—  
9,872,318  

$1,274,790 
— 
1,220,566 
2,495,356 

7,146,676 
— 
58,526 

7,205,202 

TOTAL LIABILITIES 

12,083,394   

9,700,558 

CONTINGENT LIABILITIES AND COMMITMENTS (See Note 11) 

STOCKHOLDERS’ EQUITY: 

Common stock, $0.10 par value per share, 15,000,000 and 11,000,000 shares 
authorized, 7,299,009 and 7,299,009 shares issued and 7,218,836 and 
7,212,919 shares outstanding, as of December 31, 2020 and 2019, 
respectively 
Additional paid-in capital 
Accumulated deficit 
Treasury stock, at cost, 80,173 and 86,090 shares as of December 31, 2020 
and 2019, respectively 
Accumulated other comprehensive loss 

Total stockholders’ equity 

TOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY 

729,901 
31,372,093   
(3,660,402)   

(175,392) 
—   
28,266,200   
$40,349,594   

729,901 
31,131,893 
(2,638,285) 

(188,336) 
(43,895) 
28,991,278 
$38,691,836 

The accompanying notes are an integral part of these financial statements. 

F-3 

 
 
 
 
 
 
 
  
 
  
 
 
  
 
   
 
   
 
 
   
 
   
 
 
   
 
   
 
 
  
 
 
   
 
   
 
 
 
  
 
  
 
 
 
ImmuCell Corporation 

STATEMENTS OF OPERATIONS 

Product sales 
Costs of goods sold 
Gross margin 

OPERATING EXPENSES: 
Product development expenses 
Sales and marketing expenses 
Administrative expenses 
Operating expenses 

NET OPERATING LOSS 

Other (income) expenses, net 
LOSS BEFORE INCOME TAXES 

Income tax (benefit) expense   
NET LOSS 

Basic weighted average common shares outstanding 

Basic net loss per share 

Diluted weighted average common shares outstanding 

Diluted net loss per share 

During the Years Ended December 31, 

2020 

$15,342,204   
8,479,378   
6,862,826   

2019 
$13,722,872 
6,983,152 
6,739,720 

4,354,627  
2,167,899   
1,720,653   
8,243,179   

3,687,609 
2,318,112 
1,687,907 
7,693,628 

(1,380,353)   

(953,908) 

(348,100)   
(1,032,253)   

313,505 
(1,267,413) 

(10,136)   
($1,022,117)   

28,174 
($1,295,587) 

7,213,329   
($0.14)   

7,213,329   
($0.14)   

6,818,960 
($0.19) 

6,818,960 
($0.19) 

STATEMENTS OF COMPREHENSIVE LOSS 

Net loss 
Other comprehensive income (loss): 
Interest rate swaps, before taxes 
Income tax applicable to interest rate swaps 

Other comprehensive income (loss), net of taxes 

Total comprehensive loss   

During the Years Ended December 31, 

2020 

($1,022,117)   

2019 
($1,295,587) 

58,526   
(14,631)   
43,895   
($978,222)   

(98,735) 
24,683 
(74,052) 
($1,369,639) 

The accompanying notes are an integral part of these financial statements. 

F-4 

 
 
 
 
 
 
 
   
 
   
 
 
   
 
 
 
 
 
 
   
 
 
   
 
 
   
 
 
   
 
 
 
 
 
 
   
 
 
ImmuCell Corporation 

STATEMENTS OF STOCKHOLDERS’ EQUITY 

Common Stock 

Treasury Stock 

Shares 

Amount 

Additional 
paid-in 
capital 

Accumulated 
Deficit 

Shares 

Amount 

  Accumulated 

Other 
Comprehensive 
Income (Loss) 

Total 
Stockholders’ 
Equity 

5,662,645    $566,265  $22,695,557  ($1,342,698)  
—    (1,295,587)   

—   

—   

93,683  
—   

($204,947)  
—   

$30,157   $21,744,334 
(1,295,587) 

—   

— 

— 

— 

— 

— 

— 

(74,052) 

(74,052) 

1,636,364 
—   

163,636 
—   

8,139,800 
(16,608)   

— 

— 

313,144 

— 
—   

— 

— 
(7,593)   

— 
16,611   

— 

— 

— 
—   

— 

8,303,436 
3 

313,144 

BALANCE, 

December 31, 2018 
Net loss 
Other comprehensive 
loss, net of taxes 

Public offering of 

common stock, net of 
$696,566 of offering 
costs 

Exercise of stock options 
Stock-based 

compensation 

BALANCE, 

7,299,009    $729,901   $31,131,893   ($2,638,285)   
(1,022,117) 

— 

— 

86,090   
— 

($188,336)   
— 

($43,895)    $28,991,278 
(1,022,117) 

— 

— 

— 

— 

— 

(12,935) 

253,135 

— 

— 

— 

— 

— 

43,895 

43,895 

(5,917) 

12,944 

— 

— 

— 

— 

9 

253,135 

December 31, 2019 
Net loss 
Other comprehensive 

income, net of taxes 
Exercise of stock options 
Stock-based 

compensation 

—   
— 
—   
— 

BALANCE, 

December 31, 2020 

7,299,009   

$729,901 

$31,372,093 

($3,660,402) 

80,173 

($175,392) 

— 

$28,266,200 

The accompanying notes are an integral part of these financial statements. 

F-5 

 
 
 
 
  
 
 
 
 
  
 
 
 
 
 
 
 
   
  
  
  
  
  
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
   
   
   
   
 
   
  
  
  
  
  
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ImmuCell Corporation 

STATEMENTS OF CASH FLOWS 

CASH FLOWS FROM OPERATING ACTIVITIES: 

Net loss 
Adjustments to reconcile net loss to net cash provided by operating activities:  

During the Years Ended December 31, 

2020 

2019 

($1,022,117) 

($1,295,587) 

Depreciation 
Amortization of intangible assets 
Amortization and write-off of debt issuance costs 
Forgiveness of debt 
Deferred income taxes 
Stock-based compensation 
Loss on disposal of fixed assets 
Non-cash rent expense 

Changes in: 

Trade accounts receivable 
Accrued interest income 
Inventory 
Prepaid expenses and other current assets 
Other assets 
Accounts payable and accrued expenses 

Net cash provided by operating activities 

CASH FLOWS FROM INVESTING ACTIVITIES: 

Purchase of property, plant and equipment 
Maturities of investment 
Purchases of investments 
Payment of contingent royalties related to 2016 acquisition 
Proceeds from sale of assets 
Net cash used for investing activities 

CASH FLOWS FROM FINANCING ACTIVITIES: 

Proceeds from public offering, net 
Proceeds from debt issuance 
Debt principal repayments 
Line of credit repayment 
Payments of debt issuance costs 
Proceeds from exercise of stock options 
Net cash provided by financing activities 

NET INCREASE IN CASH AND CASH  EQUIVALENTS   
BEGINNING CASH AND CASH EQUIVALENTS   
ENDING CASH AND CASH EQUIVALENTS 

2,328,179 
19,104 
102,724 
(937,700) 
(14,631) 
253,135 
39,303 
15,320 

(159,636) 
27,258 
425,742 
(61,695) 
711 
299,881 
1,315,578 

(4,072,539) 
3,449,000 
(1,992,000) 
— 
45,600 
(2,569,939) 

—  
11,537,700 
(9,573,568) 
— 
(53,136) 
9 
1,911,005 

656,644 
6,293,293 
$6,949,937 

2,248,317 
19,104 
16,976 
— 
24,684 
313,144 
2,469 
— 

(704,867) 
(27,753) 
(186,585) 
(73,749) 
(13,931) 
(88,711) 
233,511 

(1,391,446) 
7,670,000 
(10,123,000) 
(8,914) 
450,000 
(3,403,360) 

8,303,436 
— 
(861,347) 
(500,000) 
— 
3 
6,942,092 

3,772,243 
2,521,050 
$6,293,293 

The accompanying notes are an integral part of these financial statements  

F-6 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ImmuCell Corporation 
STATEMENT OF CASH FLOWS 

SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION 

CASH PAID FOR: 
Income taxes 
Interest expense 

During the Years Ended December 31, 

2020 

2019 

$4,581 
$481,408 

$3,566 
$420,956 

NON-CASH ACTIVITIES: 
Forgiveness of debt 
Change in capital expenditures included in accounts payable and accrued 

expenses 

Net change in fair value of interest rate swaps, net of taxes 
Operating lease right-of-use asset and operating lease liability 

($937,700)  

($170,220) 
($43,895) 
$1,313,698 

$— 

$97,530 
$74,052 
$— 

The accompanying notes are an integral part of these financial statements. 

F-7 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements   

1. BUSINESS OPERATIONS 

ImmuCell Corporation (the “Company”, “we”, “us”, “our”) was originally incorporated in Maine in 1982 and 

reincorporated in Delaware in 1987, in conjunction with our initial public offering of common stock. We are an 
animal health company whose purpose is to create scientifically-proven and practical products that improve the 
health and productivity of dairy and beef cattle. We manufacture and market the First Defense® product line for the 
prevention of scours in newborn dairy and beef calves. We are developing improved formulations of this product 
line providing Immediate Immunity™ to newborn calves and are in the late stages of developing Re-Tain™, a 
treatment for cows with subclinical mastitis, the most significant cause of economic loss to the dairy industry. These 
products help reduce the need to use traditional antibiotics in food producing animals. We are subject to certain risks 
associated with this stage of development including dependence on key individuals and third-party providers of 
critical goods and services, competition from other larger companies, the successful sale of existing products and the 
development and acquisition of additional commercially viable products with appropriate regulatory approvals, 
where applicable.   

The global COVID-19 pandemic has created, and continues to create, a great deal of uncertainty for us. The full 
impact of this viral outbreak on the global economy, and the duration of such impact, is very uncertain at this time. A 
combination of the conditions, trends and concerns could have a corresponding negative effect on our business and 
operations, including the supply of the colostrum we purchase to produce our First Defense® product line, the 
demand for our products in the U.S. market and our ability to penetrate or maintain a profitable presence in 
international markets. We could experience shortages in key components and needed products, backlogs and 
production slowdowns due to difficulties accessing needed supplies and labor and other restrictions affecting our 
ability to consistently deliver our products to market. Despite our best efforts and intentions, there is a risk that an 
employee could become infected and could infect others. This could lead to plant shutdowns and production 
interruptions and have other negative economic and health and safety impacts. 

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES 

(a) Basis of Presentation 

We have prepared the accompanying audited financial statements reflecting all adjustments (which are of a 
normal recurring nature) that are, in our opinion, necessary in order to ensure that the financial statements are not 
misleading. We follow accounting standards set by the Financial Accounting Standards Board (FASB). The FASB 
sets generally accepted accounting principles (GAAP) that we follow to ensure we consistently report our financial 
condition, results of operations, earnings per share and cash flows. References to GAAP in these footnotes are to the 
FASB Accounting Standards Codification™ (Codification). Accordingly, we believe that the disclosures are 
adequate to ensure that the information presented is not misleading.   

(b) Cash, Cash Equivalents and Short-Term Investments   

We consider all highly liquid investment instruments that mature within three months of their purchase dates 

to be cash equivalents. Cash equivalents are principally invested in securities backed by the U.S. government. 
Certain cash balances in excess of Federal Deposit Insurance Corporation (FDIC) limits of $250,000 per financial 
institution per depositor are maintained in money market accounts at financial institutions that are secured, in part, 
by the Securities Investor Protection Corporation. Amounts in excess of these FDIC limits per bank that are not 
invested in securities backed by the U.S. government aggregated $751,050 and $5,792,993 as of December 31, 2020 
and 2019, respectively. Short-term investments are classified as held to maturity and are comprised of certificates of 
deposit that mature in more than three months from their purchase dates and not more than twelve months from the 
balance sheet date. Short-term investments are held at different financial institutions that are insured by the FDIC, 
within the FDIC limits per financial institution. We account for investments in marketable securities in accordance 
with Codification Topic 320, Investments — Debt and Equity Securities. See Note 3. 

F-8 

 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

(c) Trade Accounts Receivable, net 

Accounts receivable are carried at the original invoice amount less an estimate made for doubtful collection 
when applicable. Management determines the allowance for doubtful accounts on a monthly basis by identifying 
troubled accounts and by using historical experience applied to an aging of accounts. Accounts receivable are 
considered to be past due if a portion of the receivable balance is outstanding for more than 30 days. Past due 
accounts receivable are subject to an interest charge. Accounts receivable are written off when deemed 
uncollectible. The amount of accounts receivable written off during all periods reported was immaterial. 
Recoveries of accounts receivable previously written off are recorded as income when received. As of December 
31, 2020 and 2019, we determined that no allowance for doubtful accounts was necessary. See Note 4. 

(d) Inventory 

Inventory includes raw materials, work-in-process and finished goods and is recorded at the lower of cost, on 
the first-in, first-out method, or net realizable value (determined as the estimated selling price in the normal course 
of business, less reasonably predictable costs of completion, disposal and transportation). Work-in-process and 
finished goods inventories include materials, labor and manufacturing overhead. At each balance sheet date, we 
evaluate our ending inventories for excess quantities and obsolescence. Inventories that we consider excess or 
obsolete are written down to estimated net realizable value. Once inventory is written down and a new cost basis is 
established, it is not written back up if demand increases. We believe that supplies and raw materials for the 
production of our products are available from more than one vendor or farm. Our policy is to maintain more than 
one source of supply for the components used in our products when feasible. See Note 5. 

  (e) Property, Plant and Equipment 

We depreciate property, plant and equipment on the straight-line method by charges to operations and costs of 

goods sold in amounts estimated to expense the cost of the assets from the date they are first put into service to the 
end of the estimated useful lives of the assets. The facility we have constructed to produce the Nisin Drug Substance 
for Re-Tain™ is being depreciated over 39 years from when a certificate of occupancy was issued during the fourth 
quarter of 2017. We began depreciating the equipment for our Nisin Drug Substance facility when it was placed in 
service during the third quarter of 2018. Approximately 88% of these assets are being depreciated over ten years. 
We began depreciating the leasehold improvements to our new First Defense® production facility at 175 Industrial 
Way over the remainder of the ten-year lease term beginning when a certificate of occupancy was issued during the 
second quarter of 2020. Significant repairs to fixed assets that benefit more than a current period are capitalized and 
depreciated over their useful lives. Insignificant repairs are expensed when incurred. See Note 7. 

(f) Intangible Assets and Goodwill 

We amortize intangible assets on the straight-line method by charges to costs of goods sold in amounts 

estimated to expense the cost of the assets from the date they are first put into service to the end of the estimated 
useful lives of the assets. We have recorded intangible assets related to customer relationships, non-compete 
agreements and developed technology, each with defined useful lives. We have classified as goodwill the amounts 
paid in excess of fair value of the net assets (including tax attributes) acquired in purchase transactions. We assess 
the impairment of intangible assets and goodwill that have indefinite lives at the reporting unit level on an annual 
basis (as of December 31st) and whenever events or changes in circumstances indicate that the carrying value of the 
asset may not be recoverable. We would record an impairment charge if such an assessment were to indicate that the 
fair value of such assets was less than the carrying value. Judgment is required in determining whether an event has 
occurred that may impair the value of goodwill or identifiable intangible assets. Factors that could indicate that an 
impairment may exist include significant under-performance relative to plan or long-term projections, significant 
changes in business strategy and significant negative industry or economic trends. Although we believe intangible 
assets and goodwill are properly stated in the accompanying financial statements, changes in strategy or market 
conditions could significantly impact these judgments and require an adjustment to the recorded balance. No 
goodwill impairments were recorded during the years ended December 31, 2020 or 2019. See Notes 2(g) and 8 for 
additional disclosures. 

F-9 

 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

(g)Valuation of Long-Lived Assets 

We periodically evaluate our long-lived assets, consisting principally of fixed assets, operating lease right-of-
use asset and amortizable intangible assets, for potential impairment. In accordance with the applicable accounting 
guidance for the treatment of long-lived assets, we review the carrying value of our long-lived assets or asset group 
that is held and used, including intangible assets subject to amortization, for impairment whenever events and 
circumstances indicate that the carrying value of the assets may not be recoverable. Under the held for use approach, 
the asset or asset group to be tested for impairment should represent the lowest level for which identifiable cash 
flows are largely independent of the cash flows of other groups of assets and liabilities. We evaluate our long-lived 
assets whenever events or circumstances suggest that the carrying amount of an asset or group of assets may not be 
recoverable. No impairment was recognized during the years ended December 31, 2020 or 2019. 

(h) Fair Value Measurements 

In determining fair value measurements, we follow the provisions of Codification Topic 820, Fair Value 

Measurements and Disclosures. Codification Topic 820 defines fair value, establishes a framework for measuring 
fair value under GAAP and enhances disclosures about fair value measurements. The topic provides a consistent 
definition of fair value which focuses on an exit price, which is the price that would be received to sell an asset or 
paid to transfer a liability in an orderly transaction between market participants at the measurement date. The topic 
also prioritizes, within the measurement of fair value, the use of market-based information over entity-specific 
information and establishes a three-level hierarchy for fair value measurements based on the nature of inputs used in 
the valuation of an asset or liability as of the measurement date. As of December 31, 2020 and 2019, the carrying 
amounts of cash and cash equivalents, short-term investments, accounts receivable, inventory, other assets, accounts 
payable and accrued liabilities approximate fair value because of their short-term nature. The amount outstanding 
under our bank debt facilities is measured at carrying value in our accompanying balance sheets. Our bank debt 
facilities are valued using Level 2 inputs. The estimated fair value of our bank debt facilities approximates their 
carrying value based on similar instruments with similar maturities. The three-level hierarchy is as follows: 

Level 1 — Pricing inputs are quoted prices available in active markets for identical assets or liabilities   

as of the measurement date. 

Level 2 — Pricing inputs are quoted prices for similar assets or liabilities, or inputs that are observable, either 
directly or indirectly, for substantially the full term through corroboration with observable market 
data. 

Level 3 — Pricing inputs are unobservable for the assets or liabilities, that is, inputs that reflect the reporting 
entity’s own assumptions about the assumptions market participants would use in pricing the asset 
or liability. 

In certain cases, the inputs used to measure fair value may fall into different levels of the fair value hierarchy. 

In such cases, the level of an asset or liability within the fair value hierarchy is based on the lowest level of input 
that is significant to the fair value measurement. Our assessment of the significance of a particular input to the fair 
value measurement in its entirety requires judgment and considers factors specific to the investment. From time to 
time, we also hold money market mutual funds in a brokerage account, which are classified as cash equivalents and 
measured at fair value. The fair value of these investments is based on their closing published net asset value. 

We assess the levels of the investments at each measurement date, and transfers between levels are recognized 
on the actual date of the event or change in circumstances that caused the transfer in accordance with our accounting 
policy regarding the recognition of transfers between levels of the fair value hierarchy. During the years ended 
December 31, 2020 and 2019, there were no transfers between levels. As of December 31, 2020 and 2019, our Level 
1 assets measured at fair value by quoted prices in active markets consisted of bank savings accounts and money 
market funds. As of December 31, 2020 and 2019, our bank certificates of deposit were classified as Level 2 and 
were measured by other significant observable inputs. As of December 31, 2019, our interest rate swaps were 
classified as Level 2 and were measured by observable market data in combination with expected cash flows for 
each instrument. There were no assets or liabilities measured at fair value on a nonrecurring basis as of December 
31, 2020 or 2019. 

F-10 

 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

As of December 31, 2020 

Level 1 

Level 2 

Level 3 

Total 

Assets: 

Cash and money market accounts 
Bank certificates of deposit 
Total 

$6,949,937   
—  
$6,949,937  

$—   
996,495  
$996,495  

$—   
—  
$—  

$6,949,937 
996,495 
$7,946,432 

Liabilities: 
          Bank debt 

Assets: 

$—  

($9,497,486)  

$—  

($9,497,486) 

As of December 31, 2019 

Level 1 

Level 2 

Level 3 

Total 

Cash and money market accounts 
Bank certificates of deposit 
Total 

$6,293,293   
—   
$6,293,293   

$—   
2,480,753   
$2,480,753   

$—   
—   
$—   

$6,293,293 
2,480,753 
$8,774,046 

Liabilities: 

Interest rate swaps 

(i) Concentration of Risk 

$—   

($58,526)   

$—   

($58,526) 

Concentration of credit risk with respect to accounts receivable is principally limited to certain customers to 

whom we make substantial sales. To reduce risk, we routinely assess the financial strength of our customers and, as 
a consequence, believe that our accounts receivable credit risk exposure is limited. We maintain an allowance for 
potential credit losses when deemed necessary, but historically we have not experienced significant credit losses 
related to an individual customer or groups of customers in any particular industry or geographic area. Sales to 
significant customers that amounted to 10% or more of total product sales are detailed in the following table: 

Company A 
Company B 

During the Years Ended December 31,   

2020 

2019 

41%   
30%   

42%  
27%   

Trade accounts receivable due from significant customers amounted to the percentages of total trade accounts 

receivable as detailed in the following table: 

Company A 
Company B 

(j) Revenue Recognition 

As of December 31, 

2020 

2019 

48%   
27%   

28% 
48% 

We recognize revenue in accordance with Accounting Standards Codification (ASC) 606, Revenue from 
Contracts with Customers. ASC 606 is a single comprehensive model for companies to use in accounting for revenue 
arising from contracts with customers. The core principle is that we recognize the amount of revenue to which we 
expect to be entitled for the transfer of promised goods or services to customers when a customer obtains control of 

F-11 

 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
   
   
 
  
  
  
 
  
  
  
 
 
 
 
 
 
 
 
   
   
   
 
   
   
   
 
   
   
   
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

promised goods or services in an amount that reflects the consideration we expect to receive in exchange for those goods 
or services. In addition, the standard requires disclosure of the nature, amount, timing and uncertainty of revenue and cash 
flows arising from contracts with customers. We conduct our business with customers through valid purchase orders or sales 
orders which are considered contracts and are not interdependent on one another. A performance obligation is a promise in a 
contract to transfer a distinct product to the customer. The transaction price is the amount of consideration we expect to 
receive under the arrangement. Revenue is measured based on consideration specified in a contract with a customer. The 
transaction price of a contract is allocated to each distinct performance obligation and recognized when or as the customer 
receives the benefit of the performance obligation. Product transaction prices on a purchase or sales order are discrete and 
stand-alone. We recognize revenue when we satisfy a performance obligation in a contract by transferring control over a 
product to a customer when product delivery occurs. Amounts due are typically paid approximately 30 days from the time 
control is transferred. Shipping and handling costs associated with outbound freight after control over a product has 
transferred to a customer are accounted for as a fulfillment cost in costs of goods sold. We do not bill for or collect sales tax 
because our sales are generally made to distributors and thus our sales to them are not subject to sales tax. We 
generally have experienced an immaterial amount of product returns. We have enhanced disclosures related to 
disaggregation of revenue sources and accounting policies prospectively as a result of adopting this standard. See Note 
14. 

(k) Expense Recognition   

We do not incur costs in connection with product sales to customers that are eligible for capitalization. Advertising 

costs are expensed when incurred, which is generally during the month in which the advertisement is published. 
Advertising expenses amounted to $29,083 and $58,483 during the years ended December 31, 2020 and 2019, 
respectively. All product development expenses are expensed as incurred, as are all related patent costs. We 
capitalize costs to produce inventory during the production cycle, and these costs are charged to costs of goods sold 
when the inventory is sold to a customer.   

(l) Income Taxes 

We account for income taxes in accordance with Codification Topic 740, Income Taxes, which requires that 

we recognize a current tax liability or asset for current taxes payable or refundable and a deferred tax liability or 
asset for the estimated future tax effects of temporary differences and carryforwards to the extent they are realizable. 
During the second quarter of 2018, we assessed our historical and near-term future profitability and decided to 
record $563,252 in non-cash income tax expense to create a full valuation allowance against our net deferred tax 
assets (which consist largely of net operating loss carryforwards and federal and state tax credits). At that time, we 
had incurred a net loss for six consecutive quarters, had not been profitable on a year-to-date basis since the nine-
month period ended September 30, 2017 and projected additional net losses for some period going forward before 
returning to profitability. We consider future taxable income and feasible tax planning strategies in assessing the 
need for a valuation allowance at each quarter end. If we determine that we would be able to realize our deferred tax 
assets in the future in excess of the net recorded amount over a reasonably short period of time, a reduction of the 
valuation allowance would increase income in the period such determination was made. Likewise, if we determine 
that we would not be able to realize all or part of our net deferred tax asset in the future, an increase to the valuation 
allowance would be charged to income in the period such determination was made. 

Codification Topic 740-10 clarifies the accounting for income taxes by prescribing a minimum recognition 

threshold that a tax position must meet before being recognized in the financial statements. In the ordinary course of 
business, there are transactions and calculations where the ultimate tax outcome is uncertain. In addition, we are 
subject to periodic audits and examinations by the Internal Revenue Service and other taxing authorities. With few 
exceptions, we are no longer subject to income tax examinations by tax authorities for years before 2017. We have 
evaluated the positions taken on our filed tax returns. We have concluded that no uncertain tax positions existed as 
of December 31, 2020 or 2019. Although we believe that our estimates are reasonable, actual results could differ 
from these estimates. See Note 16. 

(m) Stock-Based Compensation   

We account for stock-based compensation in accordance with Codification Topic 718, Compensation-Stock 

F-12 

 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

Compensation, which generally requires us to recognize non-cash compensation expense for stock-based payments 
using the fair-value-based method. The fair value of each stock option grant has been estimated on the date of grant 
using the Black-Scholes option pricing model. Accordingly, we recorded compensation expense pertaining to stock-
based compensation of $253,135 and $313,144 during the years ended December 31, 2020 and 2019, respectively. 

(n) Net Loss Per Common Share 

Net loss per common share has been computed in accordance with Codification Topic 260-10, Earnings Per 

Share. The weighted average number of shares outstanding was 7,213,329 and 6,818,960 during the years ended 
December 31, 2020 and 2019, respectively. The net loss per share has been computed by dividing the net loss by the 
weighted average number of common shares outstanding during the period. All stock options have been excluded 
from the denominator in the calculation of dilutive earnings per share when we are in a loss position because their 
inclusion would be anti-dilutive. Outstanding stock options that were not included in this calculation because the 
effect would be anti-dilutive totaled 414,000 and 388,500 as of December 31, 2020 and 2019, respectively. 

(o) Use of Estimates 

The preparation of financial statements in conformity with GAAP requires management to make estimates and 

assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and 
liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the 
period. Although we regularly assess these estimates, actual amounts could differ from those estimates and are 
subject to change in the near term. Changes in estimates are recorded during the period in which they become 
known. Significant estimates include our inventory valuation, valuation of goodwill and long-lived assets, valuation 
of deferred tax assets, accrued expenses, costs of goods sold and useful lives of intangible assets. 

(p) New Accounting Pronouncements Adopted 

In February 2016, the FASB issued ASU 2016-02, Leases (Topic 842). The guidance in this ASU supersedes 

the leasing guidance in Topic 840, Leases. Under the new guidance, lessees are required to recognize lease assets 
and lease liabilities on the balance sheet for all leases with terms longer than 12 months. Leases are classified as 
either finance or operating, with classification affecting the pattern of expense recognition in the income statement. 
This ASU and its amendments became effective for fiscal years beginning after December 15, 2018, including 
interim periods within those fiscal years. Early adoption was permitted. We elected to adopt this ASU effective 
January 1, 2019. In July 2018, the FASB issued ASU 2018-10, Codification improvements to Topic 842, Leases. 
The amendments in ASU 2018-10 provide more clarification in regard to the application and requirements of Topic 
842. In July 2018, the FASB issued ASU 2018-11, Topic 842, Leases - Targeted improvements. The amendments in 
ASU 2018-11 provide for the option to adopt the standard prospectively and recognize a cumulative-effect 
adjustment to the opening balance of retained earnings as well as offer a new practical expedient that allows us to 
elect, by class of underlying asset, to not separate non-lease and lease components in certain circumstances and 
instead to account for those components as a single item. Based on our current lease agreements and a review of all 
of our material vendor relationships for potential embedded lease obligations, we concluded that we were not subject to 
material lease obligations as of December 31, 2019, and the adoption of Topic 842 beginning did not have a material 
impact on our financial statements as of January 1, 2019. The lease we entered into on September 12, 2019 to expand 
our production capacity for the First Defense® product line with a Possession Date of November 15, 2019 and a 
Commencement Date of February 13, 2020 has been accounted for in accordance with Topic 842 beginning during the 
first quarter of 2020. The only material lease pursuant to which we are the lessee relates to real estate property. All 
leases are classified as operating leases, and therefore, were previously not recognized on our balance sheets. With the 
adoption of Topic 842, operating lease agreements are required to be recognized on our balance sheets as a right-of-use 
(ROU) asset with a corresponding lease liability. If at a lease inception date or at some later date during the term of a 
lease, we consider the exercising of a renewal option to be reasonably certain, we would include the extended term 
in the calculation of the ROU asset and lease liability. Regarding the discount rate, Topic 842 requires the use of the 
rate implicit in the lease whenever this rate is readily determinable. As this rate is rarely determinable, we utilize our 
incremental borrowing rate at lease inception, on a collateralized basis, over a similar term. See Note 12. We elected 

F-13 

 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

the following practical expedients in conjunction with implementation of Topic 842: 

• 

Inclusion of both the lease and non-lease components for all classes of underlying assets as a single 
component. 

•  Election to exclude short-term lease (i.e., lease with initial terms of twelve months or less) from capi-

talization on our balance sheets. 

In August 2018, the FASB issued ASU 2018-13, Fair Value Measurement (Topic 820): Disclosure 

Framework-Changes to the Disclosure Requirements for Fair Value Measurement, which modifies the disclosure 
requirements of fair value measurements. Topic 820 is effective for fiscal years beginning after December 15, 2019, 
and early adoption is permitted. The adoption of Topic 820 did not have a material impact on our financial 
statements as of January 1, 2020. 

We adopted ASU 2016-13, “Financial Instruments-Credit Losses (Topic 326): Measurement of Credit Losses 
on Financial Instruments,” effective January 1, 2020, using the modified retrospective transition method. This ASU 
amends the impairment model to utilize an expected loss methodology in place of the incurred loss methodology for 
financial instruments, including trade receivables and leased equipment. The amendment requires entities to 
consider a broader range of information to estimate expected credit losses, which may result in earlier recognition of 
losses. The adoption of Topic 326 did not have a material impact on our financial statements as of January 1, 2020. 

(q) New Accounting Pronouncements Not Yet Adopted 

In December 2019, the FASB issued ASU 2019-12, Income Taxes (Topic 740): Simplifying the Accounting for 

Income Taxes. The new guidance is intended to simplify the accounting for income taxes by removing certain 
exceptions and by updating accounting requirements around goodwill recognized for tax purposes and the allocation 
of current and deferred tax expense among legal entities, among other minor changes. ASU 2019-12 is effective for 
fiscal years beginning after December 15, 2020, including interim periods within those fiscal years. Early adoption is 
permitted. We do not expect the adoption of ASU 2019-12 to have a material impact on our financial statements. 

In March 2020, the FASB issued ASU 2020-04, Facilitation of the Effects of Reference Rate Reform on 

Financial Reporting. ASU 2020-04 is intended to provide optional expedients and exceptions to the U.S. GAAP 
guidance on contract modifications and hedge accounting to ease the financial reporting burdens related to the 
discontinuation of the London Interbank Offered Rate (LIBOR) or by another reference rate expected to be 
discontinued. The relief offered by this guidance, if adopted, is available to companies for the period March 12, 2020 
through December 31, 2022. We do not expect the discontinuation of LIBOR to have a material impact on our 
financial statements. 

3. CASH, CASH EQUIVALENTS AND SHORT-TERM INVESTMENTS   

Cash, cash equivalents and short-term investments (at amortized cost plus accrued interest) consisted of the 

following: 

Cash and cash equivalents 
Short-term investments 

Total 

As of   
December 31, 2020 

As of   
December 31, 2019 
$6,293,293 
2,480,753 
$8,774,046 

$6,949,937   
996,495   
$7,946,432   

  Held to maturity securities (certificates of deposit) are carried at amortized cost. As of December 31, 2019, 
we were required to maintain at least $2,000,000 of otherwise unrestricted cash, cash equivalents and short-term 
investments in compliance with a bank debt covenant. We were not subject to such a requirement as of December 
31, 2020. 

4. TRADE ACCOUNTS RECEIVABLE, net 

Trade accounts receivable amounted to $1,796,801 and $1,637,165 as of December 31, 2020 and 2019, 

F-14 

 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

respectively. No allowance for bad debt and product returns was recorded as of December 31, 2020 or 2019.   

5. INVENTORY 

Inventory consisted of the following: 

Raw materials 
Work-in-process 
Finished goods 

Total 

6. PREPAID EXPENSES AND OTHER CURRENT ASSETS 

Prepaid expenses and other current assets consisted of the following: 

Prepaid expenses 
Other receivables 
Security deposits  

Total 

7. PROPERTY, PLANT AND EQUIPMENT, net 

Property, plant and equipment consisted of the following: 

Laboratory and manufacturing equipment 
Building and improvements 
Office furniture and equipment 
Construction in progress 
Land 

Property, plant and equipment, gross 

Accumulated depreciation 

Property, plant and equipment, net 

Estimated Useful 
Lives   
(in years) 
3-10 
10-39 
3-10 
n/a 
n/a 

As of   
December 31, 2020 

As of   
December 31, 2019 
$791,558 
1,207,457 
519,241 
$2,518,256 

$631,019   
1,438,482   
23,013   
$2,092,514   

As of   
December 31, 2020 

As of   
December 31, 2019 
$218,232 
40,534 
800 
                  $321,261                     $259,566 

$252,840   
67,621   
800   

As of   
December 31, 2020 

As of   
December 31, 2019 
$15,437,724 
17,078,829 
719,323 
1,124,189 
516,867 
34,876,932 
(9,611,194) 
$25,265,738 

$15,786,620   
18,999,500   
779,720   
2,337,620   
516,867   
38,420,327   
(11,665,352)   
$26,754,975   

As of December 31, 2020 and 2019, construction in progress consisted principally of payments toward the 
First Defense® production capacity expansion project and equipment needed to bring the formulation and aseptic 
filling for Re-Tain™ in-house. Property, plant and equipment disposals were approximately $358,924 and $62,055 
during the years ended December 31, 2020 and 2019, respectively. Depreciation expense was $2,328,179 and 
$2,248,317 during the years ended December 31, 2020 and 2019, respectively.   

F-15 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

8. INTANGIBLE ASSETS 

The developed technology intangible assets of $191,040 (which include an immaterial amount of value 
associated with customer relationships and a non-compete agreement and was valued using the relief from royalty 
method) are being amortized to costs of goods sold over their useful lives, which are estimated to be 10 years. 
Intangible amortization expense was $19,104 during both of the years ended December 31, 2020 and 2019.    The net 
value of these intangibles was $95,520 and $114,624 as of December 31, 2020 and 2019, respectively. Intangible 
asset amortization expense is estimated to be $19,104 per year through December 31, 2025.   

Intangible assets as of December 31, 2020 consisted of the following: 

Developed technology 
Customer relationships 
Non-compete agreements 

Total 

Gross Carrying 
Value 

  Accumulated 
Amortization 

Net Book   
Value 

$184,100   
1,300   
5,640   
$191,040   

($92,050)   
(650)   
(2,820)   
($95,520)   

$92,050 
650 
2,820 
$95,520 

            Intangible assets as of December 31, 2019 consisted of the following: 

Developed technology 
Customer relationships 
Non-compete agreements 

Total 

Gross Carrying 
Value 

  Accumulated 
Amortization 

Net Book   
Value 

$184,100   
1,300   
5,640   
$191,040   

($73,640)   
(520)   
(2,256)   
($76,416)   

$110,460 
780 
3,384 
$114,624 

9. ACCOUNTS PAYABLE AND ACCRUED EXPENSES 

Accounts payable and accrued expenses consisted of the following: 

Accounts payable – trade 
Accounts payable – capital 
Accrued payroll 
Accrued professional fees 
Accrued other 

Total 

10. BANK DEBT 

As of   
December 31, 2020 

As of   
December 31, 2019 
$401,958 
170,220 
399,501 
73,781 
175,106 
$1,220,566 

$602,347   
—   
525,499   
84,900   
137,481   
$1,350,227   

Prior to a refinancing with Gorham Savings Bank (GSB) during the first quarter of 2020, we had in place five 
different credit facilities and a line of credit with TD Bank N.A. (Loans #1 to #5). During the first quarter of 2020, 
we closed on a debt financing with GSB aggregating $8,600,000 and a $1,000,000 line of credit. The debt is 
comprised of a $5,100,000 mortgage note (Loan #6) that bears interest at a fixed rate of 3.50% per annum (with a 
10-year term and 25-year amortization schedule and a balloon principal payment of $3,145,888 due during the first 
quarter of 2030) and a $3,500,000 note (Loan #7) that bears interest at a fixed rate of 3.50% per annum (with a 7-
year term and amortization schedule). The line of credit is available as needed through March 10, 2022. Interest on 
borrowings against the line of credit is variable at the rate of the one-month LIBOR plus 2.15% per annum. There 
was no outstanding balance under this line of credit as of December 31, 2020. In connection with these three credit 
facilities, we incurred debt issuance costs of $39,789. The amortization of debt issuance costs is being recorded as a 
component of interest expense, included with other (income) expenses, net, and is being amortized over the 
underlying terms of the two notes and the line of credit. The proceeds from the debt refinancing were used to repay 
all bank debt outstanding at the time of closing (Loans #1 to #5) and to provide some additional working capital. We 

F-16 

 
 
 
 
 
 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

were required by bank debt covenant to maintain $1,400,000 in escrow (a non-current asset). During the fourth 
quarter of 2020, we closed on a $1,500,000 note with GSB (Loan #10) that bears interest at a fixed rate of 3.50% per 
annum (with a 7-year term and amortization schedule). In connection with this note, we incurred debt issuance costs 
of $13,347. The amortization of these debt issuance costs is also being recorded as a component of interest expense, 
included with other (income) expense, net, and is being amortized over the underlying term of the note. Proceeds of 
$624,167 were used to prepay a portion of the then outstanding principal on our mortgage loan (Loan #6), which 
reduced the outstanding balance to 80% of the most recent appraised value of the property securing the debt, which 
allowed GSB to release the $1,400,000 that had been held in escrow. The remaining proceeds were available for 
general working capital purposes. These three new credit facilities are secured by liens on substantially all of our 
assets and are subject to certain restrictions and financial covenants.   

During the second quarter of 2020, we received $937,700 in support from the federal government under the 
Paycheck Protection Program (PPP) (Loan #8). We used the proceeds only for eligible payroll costs incurred and 
paid during the 24-week period beginning April 13, 2020. Our obligation to repay the principal was forgiven, and 
we recognized this amount as part of other (income) expenses, net, during the fourth quarter of 2020. This 
forgiveness of indebtedness, in accordance with the CARES Act, does not give rise to federal taxable income, and 
these forgiven expenses may be deducted for federal tax return purposes. The state taxability of the PPP loan 
forgiveness varies by tax jurisdiction.   

During the second quarter of 2020, we received a $500,000 loan from the Maine Technology Institute (Loan 

#9) that is subordinated to all other bank debt. The first 27 months of this loan are interest-free with no interest 
accrual or required principal payments. Principal and interest payments at 5% per annum are due quarterly over the 
final five years of the loan, beginning during the fourth quarter of 2022 and continuing through the third quarter of 
2027. The loan may be prepaid without penalty at any time. 

Debt proceeds received and principal repayments made during the years ended December 31, 2020 and 2019 

are reflected in the following tables by year and by loan: 

Loan #1 
Loan #2 
Loan #3 
Loan #4 
Loan #5 
Loan #6 
Loan #7 
Loan #8(1) 
Loan #9 
Loan #10 
Total 

During the Year   
Ended December 31, 2020 

During the Year   
Ended December 31, 2019 

Proceeds from 
Debt Issuance 

  Debt Principal 
Repayments 

Proceeds from   
Debt Issuance 

  Debt Principal 
Repayments 

$—   
—   
—   
—   
—   
5,100,000   
3,500,000   
937,700   
500,000   
                1,500,000   
$11,537,700   

($493,696)   
(2,143,771)   
(3,236,429)   
(2,336,000)   
(309,182)   
(720,001)   
(334,489)   
(937,700)   
—   
—   
($10,511,268)   

$—   
—   
—   
—   
—   
—   
—   
—   
—   
—   
$—   

($68,908) 
(89,997) 
(562,857) 
(128,000) 
(11,585) 
— 
— 
— 
— 
— 
($861,347) 

(1) Loan #8 was forgiven by the federal government during the fourth quarter of 2020. 

F-17 

 
 
 
 
 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

Principal payments (net of debt issue costs) due under bank loans outstanding as of December 31, 2020 

(excluding our $1,000,000 line of credit) are reflected in the following table by the year that payments are due: 

During the Years Ending December 31, 

  Total 

Loan #6 
Loan #7 
Loan #9 
Loan #10 
Subtotal 
Debt issuance costs   
Total 

2021 
$116,103   
460,607   
—   
191,792   
768,502   
(8,165)   
$760,337   

2022 
$120,291   
477,220   
22,160   
198,710   
818,381   
(6,500)   
$811,881   

   2026 and 
After 

2024 

2023 
2025 
$124,629    $128,725    $133,768    $3,756,484   $4,380,000 
690,410    3,165,510 
494,433   
512,102    530,738    
91,446   
96,104    101,001     189,289   
500,000 
213,217    220,994    
205,878   
469,409    1,500,000 
950,148    986,501     5,105,592    9,545,510 
916,386   
(48,024) 
(6,093)   
(6,093)   
$910,293    $944,055    $980,408    $5,090,512   $9,497,486 

(15,080)   

(6,093)    

11. CONTINGENT LIABILITIES AND COMMITMENTS 

Our bylaws, as amended, in effect provide that the Company will indemnify its officers and directors to the 

maximum extent permitted by Delaware law. In addition, we make similar indemnity undertakings to each director 
through a separate indemnification agreement with that director. The maximum payment that we may be required to 
make under such provisions is theoretically unlimited and is impossible to determine. We maintain directors’ and 
officers’ liability insurance, which may provide reimbursement to the Company for payments made to, or on behalf 
of, officers and directors pursuant to the indemnification provisions. Our indemnification obligations were 
grandfathered under the provisions of Codification Topic 460, Guarantees. Accordingly, we have recorded no 
liability for such obligations as of December 31, 2020. Since our incorporation, we have had no occasion to make 
any indemnification payment to any of our officers or directors for any reason. 

The development, manufacturing and marketing of animal health care products entails an inherent risk that 
liability claims will be asserted against us during the normal course of business. We are aware of no such claims 
against us as of the date of this filing. We feel that we have reasonable levels of liability insurance to support our 
operations. 

We enter into agreements with third parties in the ordinary course of business under which we are obligated to 

indemnify such third parties from and against various risks and losses. The precise terms of such indemnities vary 
with the nature of the agreement. In many cases, we limit the maximum amount of our indemnification obligations, 
but in some cases those obligations may be theoretically unlimited. We have not incurred material expenses in 
discharging any of these indemnification obligations, and based on our analysis of the nature of the risks involved, 
we believe that the fair value of the liabilities potentially arising under these agreements is minimal. Accordingly, 
we have recorded no liabilities for such obligations as of December 31, 2020. 

We are committed to purchasing certain key parts (syringes) and services (formulation, aseptic filling and final 

packaging of Drug Product) pertaining to Re-Tain™, our Nisin-based intramammary treatment of subclinical 
mastitis in lactating dairy cows, exclusively from contractors. We are investing in the necessary equipment to 
perform the Drug Product formulation and aseptic filling services in-house. 

During the second quarter of 2009, we entered into an exclusive and perpetual (unless terminated for cause) 

license with the Baylor College of Medicine covering the underlying rotavirus vaccine technology used to generate 
the specific antibodies for our product line extension, Tri-Shield First Defense®. The license was subject to a royalty 
equal to 4% of the sales of the First Defense® product line realized above the average of the sales of our bivalent 
product line for the years ended December 31, 2016 and 2015, plus a growth assumption of 6% per year. Earned 
royalties due were subject to annual minimums of $5,000, $10,000 and $15,000 for the years ending December 31, 
2017, 2018 and 2019, respectively. Royalties of $76,876 were paid for the year ended December 31, 2019. No further 
royalties are due under this license.     

During the first quarter of 2020, we entered into a Severance Agreement with our President and CEO. Under 

the terms of this agreement, we agree to pay this executive (or his estate) nine months of his then current salary plus 
any accrued and unused paid time off in the event of the involuntary termination of his employment by the Company 
(except for cause) or in the event of termination by him for good reason. 

F-18 

 
 
 
 
  
 
 
 
 
 
 
 
  
  
  
  
  
  
  
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

In addition to the commitments discussed above, we had committed $218,000 to increase our production 

capacity for the First Defense® product line, $763,000 to construct and equip our own Drug Product formulation 
and aseptic filling facility for Re-Tain™, $1,188,000 to the purchase of inventory, $123,000 to other capital 
expenditures and $438,000 to other obligations as of December 31, 2020. 

12. OPERATING LEASE 

On September 12, 2019, we entered into a lease covering approximately 14,300 square feet of office and 
warehouse space with a Possession Date of November 15, 2019 and a Commencement Date of February 13, 2020. 
The property is located at 175 Industrial Way in Portland, which is a short distance from our headquarters and 
manufacturing facility at 56 Evergreen Drive. We renovated this space to meet our needs in expanding our 
production capacity for the First Defense® product line. The lease term is ten years with a right to renew for a 
second ten-year term and a right of first offer to purchase. At this time, we are not reasonably assured that we would 
exercise this renewal option in place of other real estate options. A 10-year period is reflected in the right-of-use 
(ROU) asset and lease liability on our balance sheet. The total lease liability over the initial 10-year term (including 
inflationary adjustments) aggregates approximately $1,313,698 and includes real estate and personal property taxes, 
utilities, insurance, maintenance and related building and operating expenses. Our lease includes variable lease and 
non-lease components that are included in the ROU asset and lease liability. Such payments primarily include 
common area maintenance charges and increases in rent payments that are driven by factors such as future changes 
in an index, such as the Consumer Price Index. As of December 31, 2020, the balance of the operating lease ROU 
asset was $1,220,361 and the operating lease liability was $1,235,681. The calculated amount of the ROU asset and 
lease liability is impacted by the length of the lease term and the discount rate used for the present value of the 
minimum lease payments. The following table represents lease costs and other lease information. As we elected not 
to separate lease and non-lease components for all classes of underlying assets, and instead to account for them as a 
single lease component, the variable lease cost primarily represents variable payments such as real estate taxes and 
common area maintenance.   

Lease cost 

Operating lease cost 
Variable lease cost 
Total lease cost 

Operating lease 

Weighted average remaining lease term (in years) 
Weighted average discount rate 

During the Years Ended December 31,   

2020 

2019 

$104,094   
36,523   
$140,617   

9.1   
4.77%   

— 
— 
— 

— 
— 

F-19 

 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
   
 
 
   
 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

Future lease payments required under non-cancelable operating leases in effect as of December 31, 2020 

were as follows: 

During the Years Ending December 31, 
2021 
2022 
2023 
2024 
2025 
Thereafter   

Total lease payments (undiscounted cash flows) 
Less: imputed interest (discount effect of cash flows) 
Total operating lease liabilities 

13. STOCKHOLDERS’ EQUITY 

Common Stock Issuances 

Amount 
$159,396 
162,102 
165,120 
168,210 
171,383 
734,304 
1,560,515 
(324,834) 
$1,235,681 

From February 2016 to March 2019, we issued the aggregate of 4,037,861 shares of common stock in five 
different transactions raising gross proceeds of approximately $22,464,000. These funds are essential to funding our 
business growth plans. The details of each transaction are discussed below.   

On October 28, 2015, we filed a registration statement on Form S-3 (File No. 333-207635) with the Securities 

and Exchange Commission (SEC) for the potential issuance of up to $10,000,000 in equity securities (subject to 
certain limitations). This registration statement became effective on November 10, 2015. Under this form of 
registration statement, we were limited within a twelve-month period to raising gross proceeds of no more than one-
third of the market capitalization of our common stock (as determined by the high price of our common stock within 
the preceding 60 days leading up to a sale of securities) held by non-affiliates (non-insiders) of the Company. 
Having raised $10,000,000 in gross proceeds under the February 2016, July 2017 and December 2017 equity 
transactions described below, no additional equity securities can be issued under this registration statement. 

On February 3, 2016, we sold 1,123,810 shares of common stock at a price to the public of $5.25 per share in 

an underwritten public offering pursuant to our effective shelf registration statement on Form S-3, raising gross 
proceeds of approximately $5,900,000 and resulting in net proceeds to the Company of approximately $5,313,000 
(after deducting underwriting discounts and offering expenses incurred in connection with the equity financing). 

On October 21, 2016, we closed on a private placement of 659,880 shares of common stock to nineteen 

institutional and accredited investors at $5.25 per share, raising gross proceeds of approximately $3,464,000 and 
resulting in net proceeds to the Company of approximately $3,161,000 (after deducting placement agent fees and 
other expenses incurred in connection with the equity financing). 

On July 27, 2017, we issued 200,000 shares of our common stock at a price of $5.25 per share in a public, 
registered sale to two related investors pursuant to our effective shelf registration statement on Form S-3, raising 
gross proceeds of $1,050,000 and resulting in net proceeds of approximately $1,034,000 (after deducting expenses 
incurred in connection with the equity financing). 

On December 21, 2017, we sold 417,807 shares of common stock at a price to the public of $7.30 per share in 

an underwritten public offering pursuant to our effective shelf registration statement on Form S-3, raising gross 
proceeds of approximately $3,050,000 and resulting in net proceeds to the Company of approximately $2,734,000 
(after deducting underwriting discounts and offering expenses incurred in connection with the equity financing).   

On November 20, 2018, we filed a registration statement on Form S-3 (File No. 333-228479) with the Securities 
and Exchange Commission (SEC) for the potential issuance of up to $20,000,000 in equity securities (subject to certain 
limitations). This registration statement became effective on November 29, 2018. Under this form of registration 
statement, we are limited within a twelve-month period to raising gross proceeds of no more than one-third of the market 

F-20 

 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

capitalization of our common stock (as determined by the high price of our common stock within the preceding 60 
days leading up to a sale of securities) held by non-affiliates (non-insiders) of the Company. 

On March 29, 2019, we sold 1,636,364 shares of common stock at a price to the public of $5.50 per share in 

an underwritten public offering pursuant to our effective shelf registration statement on Form S-3, raising gross 
proceeds of approximately $9,000,000 and resulting in net proceeds to the Company of approximately $8,303,000 
(after deducting underwriting discounts and offering expenses incurred in connection with the equity financing).   

Stock Option Plans 

In June 2000, our stockholders approved the 2000 Stock Option and Incentive Plan (the “2000 Plan”) pursuant 

to the provisions of the Internal Revenue Code of 1986, under which employees and certain service providers may 
be granted options to purchase shares of the Company’s common stock at i) no less than fair market value on the 
date of grant in the case of incentive stock options and ii) no less than 85% of fair market value on the date of grant 
in the case of non-qualified stock options. Vesting requirements are determined by the Compensation and Stock 
Option Committee of the Board of Directors on a case by case basis. Originally, 250,000 shares of common stock 
were reserved for issuance under the 2000 Plan. The stockholders of the Company approved an increase in this 
number to 500,000 shares in June 2001. All options granted under the 2000 Plan expire no later than ten years from 
the date of grant. The 2000 Plan expired in February 2010, after which date no further options could be granted 
under the 2000 Plan. As of December 31, 2019, no options were outstanding under the 2000 Plan. 

In June 2010, our stockholders approved the 2010 Stock Option and Incentive Plan (the “2010 Plan”) pursuant 

to the provisions of the Internal Revenue Code of 1986, under which employees and certain service providers may 
be granted options to purchase shares of the Company’s common stock at no less than fair market value on the date 
of grant. At that time, 300,000 shares of common stock were reserved for issuance under the 2010 Plan and 
subsequently no additional shares have been reserved for the 2010 Plan. Vesting requirements are determined by the 
Compensation and Stock Option Committee of the Board of Directors on a case by case basis. All options granted 
under the 2010 Plan expire no later than ten years from the date of grant. The 2010 Plan expired in June 2020, after 
which date no further options can be granted under the 2010 Plan. However, options outstanding under the 2010 
Plan at that time can be exercised in accordance with their terms. As of December 31, 2020, there were 237,500 
options outstanding under the 2010 Plan. 

In June 2017, our stockholders approved the 2017 Stock Option and Incentive Plan (the “2017 Plan”) pursuant 

to the provisions of the Internal Revenue Code of 1986, under which employees and certain service providers may 
be granted options to purchase shares of the Company’s common stock at no less than fair market value on the date 
of grant. At that time, 300,000 shares of common stock were reserved for issuance under the 2017 Plan and 
subsequently no additional shares have been reserved for the 2017 Plan. Vesting requirements are determined by the 
Compensation and Stock Option Committee of the Board of Directors on a case by case basis. All options granted 
under the 2017 Plan expire no later than ten years from the date of grant. The 2017 Plan expires in March 2027, after 
which date no further options can be granted under the 2017 Plan. However, options outstanding under the 2017 
Plan at that time can be exercised in accordance with their terms. As of December 31, 2020, there were 176,500 
options outstanding under the 2017 Plan. 

F-21 

 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

Activity under the stock option plans described above was as follows: 

2000 Plan 

2010 Plan 

2017 Plan 

  Weighted 
Average 
Exercise Price 

12,500   
—   
—   
(12,500)   
—   
—   
—   
—   
—   
—   

270,000   
26,000   
(26,000)   
(15,000)   
255,000   
7,000   
(12,000)   
(12,500)   
237,500   
156,000   

111,500   
25,000   
(3,000)   
—   
133,500   
93,000   
(50,000)   
—   
176,500   
10,000   

  Aggregate 
Intrinsic 
Value(1) 
$266,020 

$6.37   
$5.90    
$6.05    
$4.37    
$6.48   
$5.03  
$5.45  
$3.15  
$6.38   
$6.31   

($516,475) 

($180,038) 
($59,290) 

Outstanding as of December 31, 2018 

Grants 
Terminations 
Exercises 

Outstanding as of December 31, 2019 

Grants 
Terminations 
Exercises 

Outstanding as of December 31, 2020 
Vested as of December 31, 2020 

Vested and expected to vest as of 
        December 31, 2020 

Reserved for future grants 
(1) 

—   
—   

237,500   
—   

176,500   
123,500    

$6.38   

($180,038) 

Intrinsic value is the difference between the fair market value as of the date indicated and as of the date of the 
option grant (which is equal to the option exercise price). 

The following table displays additional information about the stock option plans described above: 

Non-vested stock options as of January 1, 2020 
Non-vested stock options as of December 31, 2020 
Stock options granted during the year ended December 31, 2020 
Stock options that vested during the year ended December 31, 2020 
Stock options that were forfeited during the year ended December 31, 

2020 

  Weighted 
Average   
Fair Value at 
Grant Date 

  Weighted 
Average 
Exercise 
Price 

Number of 
Shares 

321,000   
248,000   
100,000   
113,000   

$3.49   
$3.25   
$2.47   
$3.48   

62,000 

$2.84 

$6.55 
$6.44 
$5.03 
$6.06 

$5.45 

During the year ended December 31, 2020, two employees exercised stock options covering 12,500 shares by 

the surrender of 6,583 stock options with a fair market value of the underlying common stock equal to $39,366 at 
the time of exercise and $9 in cash. During the year ended December 31, 2019, one director and two employees ex-
ercised stock options covering 27,500 shares by the surrender of 19,907 stock options with a fair market value of the 
underlying common stock equal to $120,172 at the time of exercise and $3 in cash. 

The weighted average remaining life of the options outstanding under the 2010 Plan and the 2017 Plan as of 
December 31, 2020 was approximately 5 years and 9 months. The weighted average remaining life of the options 
exercisable under these plans as of December 31, 2020 was approximately 5 years and 6 months. The exercise prices 
of the options outstanding as of December 31, 2020 ranged from $4.00 to $8.90 per share. The 100,000 stock 
options granted during the year ended December 31, 2020 had exercise prices between $4.00 and $6.37 per share.   
The 51,000 stock options granted during the year ended December 31, 2019 had exercise prices between $5.175 and 
$7.50 per share. The aggregate intrinsic value of options exercised during 2020 and 2019 approximated $35,375 and 
$46,091, respectively. The weighted-average grant date fair values of options granted during 2020 and 2019 were 
$2.47 and $2.93, respectively. As of December 31, 2020, total unrecognized stock-based compensation related to 
non-vested stock options aggregated $212,490, which will be recognized over a weighted average remaining period 
of 1 year and 3 months. The fair value of each stock option grant has been estimated on the date of grant using the 
Black-Scholes option pricing model, for the purpose discussed in Note 2(m), with the following weighted-average 
assumptions for the years ended December 31, 2020 and 2019: 

F-22 

 
 
 
 
 
 
 
 
   
   
   
   
   
 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

Risk-free interest rate 
Dividend yield 
Expected volatility 
Expected life 

During the Years Ended December 31, 

2020 
0.41% 
0% 
53% 
6.1 years 

2019 
1.9% 
0% 
51% 
6 years 

The risk-free interest rate is based on U.S. Treasury yields for a maturity approximating the expected option 

term, while the other assumptions are derived from averages of our historical data. 

Common Stock Rights Plan 

In September 1995, our Board of Directors adopted a Common Stock Rights Plan (the “Rights Plan”) and 

declared a dividend of one common share purchase right (a “Right”) for each of the then outstanding shares of the 
common stock of the Company. Each Right entitles the registered holder to purchase from the Company one share 
of common stock at an initial purchase price of $70.00 per share, subject to adjustment. The description and terms of 
the Rights are set forth in a Rights Agreement between the Company and American Stock Transfer & Trust Co., as 
Rights Agent. 

The Rights (as amended) become exercisable and transferable apart from the common stock upon the earlier 

of i) 10 days following a public announcement that a person or group (Acquiring Person) has, without the prior 
consent of the Continuing Directors (as such term is defined in the Rights Agreement), acquired beneficial 
ownership of 20% or more of the outstanding common stock or ii) 10 days following commencement of a tender 
offer or exchange offer the consummation of which would result in ownership by a person or group of 20% or more 
of the outstanding common stock (the earlier of such dates being called the Distribution Date). 

Upon the Distribution Date, the holder of each Right not owned by the Acquiring Person would be entitled to 
purchase common stock at a discount to the initial purchase price of $70.00 per share, effectively equal to one half 
of the market price of a share of common stock on the date the Acquiring Person becomes an Acquiring Person. If, 
after the Distribution Date, the Company should consolidate or merge with any other entity and the Company were 
not the surviving company, or, if the Company were the surviving company, all or part of the Company’s common 
stock were changed or exchanged into the securities of any other entity, or if more than 50% of the Company’s 
assets or earning power were sold, each Right would entitle its holder to purchase, at the Rights’ then-current 
purchase price, a number of shares of the acquiring company’s common stock having a market value at that time 
equal to twice the Right’s exercise price. 

At any time after a person or group becomes an Acquiring Person and prior to the acquisition by such person 
or group of 50% or more of the outstanding common stock, the Board of Directors of the Company may exchange 
the Rights (other than Rights owned by such person or group which have become void), in whole or in part, at an 
exchange ratio of one share of common stock per Right (subject to adjustment). At any time prior to 14 days 
following the date that any person or group becomes an Acquiring Person (subject to extension by the Board of 
Directors), the Board of Directors of the Company may redeem the then outstanding Rights in whole, but not in part, 
at a price of $0.005 per Right, subject to adjustment.   

At various times over the years, our Board of Directors has voted to authorize amendments of the Rights 
Agreement to extend the Final Expiration Date, which is currently September 19, 2022. Our Board of Directors also 
has voted to authorize amendments to increase the ownership threshold for determining “Acquiring Person” status to 
20%. During the second quarter of 2015, our Board of Directors also voted to authorize an amendment to remove a 
provision that prevented a new group of directors elected following the emergence of an Acquiring Person (an owner of 
more than 20% of our stock) from controlling the Rights Plan by maintaining exclusive authority over the Rights Plan 
with pre-existing directors. We did this because such provisions have come to be viewed with disfavor by Delaware 
courts. Each time that we made such amendments we entered into amendments to the Rights Agreement with the 
Rights Agent reflecting such extensions, threshold increases or provision changes. No other changes have been made 
to the terms of the Rights or the Rights Agreement. 

F-23 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

Authorized Common Stock 

At the June 14, 2018 Annual Meeting of Stockholders, our stockholders voted to approve an amendment to our 
Certificate of Incorporation to increase the number of shares of common stock authorized for issuance from 8,000,000 
to 11,000,000. At the June 10, 2020 Annual Meeting of Stockholders, our stockholders voted to approve an 
amendment to our Certificate of Incorporation to increase the number of shares of common stock authorized for 
issuance from 11,000,000 to 15,000,000. 

14. REVENUE   

We primarily offer the First Defense product line to dairy and beef producers to prevent scours in newborn 
calves. Generally, our products are promoted to veterinarians as well as dairy and beef producers by our sales team 
and then sold through distributors. Our primary market is North America. We do sell into select international regions 
and may expand this international reach in the future. There were no material changes between the allocation and 
timing of revenue recognition during the years ended December 31, 2020 and 2019. We do not have any contract 
assets for which we have satisfied the performance obligations but do not yet have the right to bill for or contract 
liabilities such as customer advances. All trade receivables on our balance sheets are from contracts with customers. 
We incur no material costs to obtain contracts. 

United States 
Other(1) 

Total product sales 

During the Years Ended December 31, 

2020 

$13,644,768   
1,697,436   
$15,342,204   

% 
89% 
11% 
100% 

2019 

  % 
    $12,191,108    89% 
1,531,764    11% 
    $13,722,872    100% 

The following table presents our product sales disaggregated by geographic area: 

  (1) Sales outside of the United States included $133,601 of non-animal health sales during the first quarter of 

2019, which product has since been divested. 

The following table presents our product sales disaggregated by major product category: 



 product line 

First Defense
Other animal health 
Other 

Total product sales 

During the Years Ended December 31, 

2020 

$15,072,446   
269,758   
—   
$15,342,204   

% 
98% 
2% 
— 
100% 

2019 

  % 
  $13,244,396    97% 
344,875    2% 
133,601    1% 
  $13,722,872    100% 

15. OTHER (INCOME) EXPENSES, NET 

Other (income) expenses, net, consisted of the following: 

Interest expense(1) 
Interest rate swap termination fee 
Debt forgiveness 
Loss on disposal of fixed assets 
Interest income 
Other (income) expenses, net 

During the Years Ended December 31, 

2020 

2019 

$412,687   
165,050   
(937,700)   
39,303   
(27,440)   
($348,100)   

$431,788   
—   
—   
2,469   
(120,752)   
$313,505   

F-24 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
   
 
 
 
 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

(1) Interest expense during 2020 included a $94,782 write-off of debt issuance costs associated with debt 

that we repaid during the first quarter of 2020. Interest expense included $7,942 and $16,976 in amortization of debt 
issuance costs during the years ended December 31, 2020 and 2019, respectively. 

16. INCOME TAXES 

Our income tax (benefit) expense aggregated ($10,136) and $28,174 (amounting to (1%) and 2% of our loss 
before income taxes, respectively) for the years ended December 31, 2020 and 2019, respectively. As of December 
31, 2020, we had federal net operating loss carryforwards of $14,642,294 of which $12,930,387 do not expire and 
$1,711,907 which expire in 2034 through 2037 (if not utilized before then) and state net operating loss 
carryforwards of $2,647,292 that expire in 2037 through 2038 (if not utilized before then). Additionally, we had 
federal general business tax credit carryforwards of $490,018 that expire in 2027 through 2039 (if not utilized before 
then) and state tax credit carryforwards of $763,350 that expire in 2023 through 2039 (if not utilized before then).   

The provision for income taxes is determined using the asset and liability approach of accounting for income 

taxes. Under this approach, deferred taxes represent the estimated future tax effects of temporary differences 
between book and tax treatment of assets and liabilities and carryforwards to the extent they are realizable. During 
the second quarter of 2018, we assessed our historical and near-term future profitability and recorded $563,252 in non-cash 
income tax expense to create a full valuation allowance against our net deferred tax assets (which consist largely of net 
operating loss carryforwards and federal and state credits) based on applicable accounting standards and practices. At that 
time, we had incurred a net loss for six consecutive quarters, had not been profitable on a year-to-date basis since the nine-
month period ended September 30, 2017 and projected additional net losses for some period going forward before returning 
to profitability. Should future profitability be realized at an adequate level, we would be able to release this valuation 
allowance (resulting in a non-cash income tax benefit) and realize these deferred tax assets before they expire. We will 
continue to assess the need for the valuation allowance at each quarter and, in the event that actual results differ from these 
estimates, or we adjust these estimates in future periods, we may need to adjust our valuation allowance. Adjustments related 
to the termination of our interest rate swap agreements were recorded during the first quarter of 2020. No subsequent 
adjustments were recorded.   

Net operating loss carryforwards, credits, and other tax attributes are subject to review and possible 
adjustment by the Internal Revenue Service. Section 382 of the Internal Revenue Code contains provisions that 
could place annual limitations on the future utilization of net operating loss carryforwards and credits in the event of 
a change in ownership of the Company, as defined. 

We file income tax returns in the U.S. federal jurisdiction and several state jurisdictions. We currently have no 

tax examinations in progress. We also have not paid additional taxes, interest or penalties as a result of tax 
examinations nor do we have any unrecognized tax benefits for any of the periods in the accompanying financial 
statements. 

The income tax provision consisted of the following: 

Current 

Federal 
State 

Current subtotal 
Deferred 

Federal 
State 

Deferred subtotal, gross 
Valuation allowance 

Deferred subtotal, net 
Income tax (benefit) expense 

  During the Years Ended December 31, 

2020 

2019 

$—   
4,496   
4,496   

(418,295)   
(24,337)   
(442,632)   
428,000   
(14,632)   
($10,136)   

$— 
3,490 
3,490 

(240,458) 
(31,205) 
(271,663) 
296,347 
24,684 
$28,174 

F-25 

 
 
 
 
 
   
 
   
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

          The actual income tax expense differs from the expected tax computed by applying the U.S. federal corporate 
tax rate of 21% to the loss before income taxes during the years ended December 31, 2020 and 2019 respectively, as 
follows: 

During the Years Ended December 31, 

2020 

2019 

$ 

% 

$ 

% 

Computed expected income tax expense rate 
State income taxes, net of federal expense 
Share-based compensation 
Tax credits 
Valuation allowance 
Paycheck Protection Program loan forgiveness 
Other 
Income tax (benefit) expense/rate 

($216,773) 
(15,674)   
30,121   
(55,180)   
428,000   
(196,917)   
16,287   
($10,136)   

(21.00%) 
(1.52)   
2.92   
(5.35)   
41.46   
(19.08)   
1.59   
(0.98%)   

($266,157) 
(21,894)   
37,811   
(27,815)   
296,347   
—   
9,882   
$28,174   

(21.00%) 
(1.73) 
2.98 
(2.19) 
23.38 
— 
0.78 
2.22% 

The significant components of our deferred tax assets, net, consisted of the following: 

Product rights 
Property, plant and equipment 
Federal general business tax credits 
Federal net operating loss carryforwards 
State tax credits carryover 
Interest rate swaps 
Prepaid expenses and other 
UNICAP 
Incentive compensation 
Valuation allowance 
Deferred tax assets, net 

17. SEGMENT INFORMATION 

As of December 31, 

2020 

$444   
(2,482,237)   
490,018   
3,074,882   
826,091   
—   
(8,814)   
11,791   
53,179   
(1,965,354)   
$—   

2019 

$6,709 
(2,306,435) 
434,838 
2,509,471 
841,558 
14,632 
(12,070) 
16,756 
31,895 
(1,537,354) 
$— 

We principally operate in the business segment described in Note 1. Pursuant to Codification Topic 280, 

Segment Reporting, we operate in one reportable business segment, that being the development, acquisition, 
manufacture and sale of products that improve the health and productivity of dairy and beef cattle. Almost all of our 
internally funded product development expenses are in support of such products. The significant accounting policies 
of this segment are described in Note 2. Our single operating segment is defined as the component of our business 
for which financial information is available and evaluated regularly by our chief operating decision-maker in 
deciding how to allocate resources and in assessing performance. Our chief operating decision-maker is our 
President and CEO. 

Sales of the First Defense® product line aggregated 98% and 97% of our total product sales during the years 

ended December 31, 2020 and 2019, respectively. Our primary customers for the majority of our product sales (89% 
during both of the years ended December 31, 2020 and 2019) are in the U.S. dairy and beef industries. Product sales 
to international customers, who are also in the dairy and beef industries, aggregated 11% and 10% of our total 
product sales during the years ended December 31, 2020 and 2019, respectively. 

F-26 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ImmuCell Corporation 
Notes to Audited Financial Statements (continued) 

18. RELATED PARTY TRANSACTIONS 

Dr. David S. Tomsche (Chair of our Board of Directors) is a controlling owner of Leedstone Inc., a domestic 
distributor of ImmuCell products (the First Defense product line and CMT), and of J-t Enterprises of Melrose, Inc., 
an exporter.  His affiliated companies purchased $668,308 and $490,323 of products from us during the year ended 
December 31, 2020 and 2019, respectively, on terms consistent with those offered to other distributors of similar sta-
tus. We made marketing-related payments of $975 to these affiliated companies during the years ended December 31, 
2020 and 2019, which represent amounts similar to those offered to other distributors of similar status. These pay-
ments are expensed as incurred. Our accounts receivable (subject to standard and customary payment terms) due from 
these affiliated companies aggregated $51,286 and $0 as of December 31, 2020 and 2019, respectively. 

19. EMPLOYEE BENEFITS 

We have a 401(k) savings plan (the Plan) in which all employees completing one month of service with the 

Company are eligible to participate. Participants may contribute up to the maximum amount allowed by the Internal 
Revenue Service. We currently match 100% of the first 3% of each employee’s salary that is contributed to the Plan 
and 50% of the next 2% of each employee’s salary that is contributed to the Plan. Under this matching plan, we paid 
$131,217 and $126,638 into the Plan for the years ended December 31, 2020 and 2019, respectively. 

20. SUBSEQUENT EVENTS 

We have evaluated subsequent events through the time of filing on March 30, 2021, the date we have issued 

this Annual Report on Form 10-K. As of the time of filing on March 30, 2021, there were no material, reportable 
subsequent events. 

F-27 

 
 
 
 
Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has 

duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. 

Signatures 

ImmuCell Corporation 
Registrant 

Date: March 30, 2021 

By: 

/s/ Michael F. Brigham 
Michael F. Brigham President, Chief Executive Officer and 
Principal Financial Officer 

POWER OF ATTORNEY 

We, the undersigned directors of ImmuCell Corporation, hereby severally constitute and appoint Michael F. 

Brigham our true and lawful attorney-in-fact and agent with full power of substitution and re-substitution, for us and 
in our stead, in any and all capacities, to sign any and all amendments to this report and all documents relating 
thereto, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the 
Securities and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do 
and perform each and every act and thing necessary or advisable to be done in and about the premises, as fully to all 
intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorney-in-fact 
and agent, or his substitute or substitutes, may lawfully do or to be done by virtue hereof. 

In accordance with the Exchange Act, this report has been signed below by the following persons on behalf of 

the Registrant and in the capacities and on the dates indicated. 

Date  March 24, 2021 

Date:   March 24, 2021 

Date:   March 24, 2021 

Date:   March 24, 2021 

Date:   March 24, 2021 

Date:   March 24, 2021 

Date:   March 24, 2021 

Date:   March 24, 2021 

By: 

/s/ Gloria J. Basse 
Gloria J. Basse, Director 

By: 

/s/ Michael F. Brigham 
Michael F. Brigham 
President, Chief Executive Officer, 
Principal Financial Officer and Director 

By: 

/s/ Bobbi Jo Brockmann 
Bobbi Jo Brockmann, Vice President of Sales 
and Marketing and Director 

By: 

/s/ David S. Cunningham 
David S. Cunningham, Director 

By: 

/s/ Steven T. Rosgen 
Steven T. Rosgen, Director 

By: 

/s/ Jonathan E. Rothschild 
Jonathan E. Rothschild, Director 

By: 

/s/ David S. Tomsche 
David S. Tomsche, DVM, Director 

By: 

/s/ Paul R. Wainman 
Paul R. Wainman, Director