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Nuformix plc

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FY2022 Annual Report · Nuformix plc
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Nuformix plc 

Annual Report and Accounts 

For the year ended 31 March 2022 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Contents 

1 

Company Information ............................................................................................................ 2 

Overview .................................................................................................................................. 3 

Non-Executive Directors’ Statement ..................................................................................... 4 

Strategic Report ....................................................................................................................... 7 

Board of Directors ................................................................................................................. 13 

Corporate Governance Report ............................................................................................. 14 

Remuneration Report ........................................................................................................... 19 

Remuneration Policy ............................................................................................................. 21 

Directors’ Report ................................................................................................................... 24 

Independent Auditor’s Report ............................................................................................. 27 

Consolidated Income Statement and Statement of Comprehensive Income .................... 33 

Consolidated Statement of Financial Position..................................................................... 34 

Consolidated Statement of Changes in Equity ...................................................................... 35 

Consolidated Statement of Cash Flows................................................................................ 36 

Notes to the Consolidated Financial Statements ................................................................. 37 

Company Statement of Financial Position .......................................................................... 58 

Company Statement of Changes in Equity ........................................................................... 59 

Company Statement of Cash Flows ..................................................................................... 60 

Notes to the Company Financial Statements ....................................................................... 61 

Notice of Annual General Meeting ....................................................................................... 65 

 
 
 
 
 
 
 
 
2 

Company Information 

Directors 

Dr Julian C Gilbert  

Ms Maddy E Kennedy  

Dr Alastair J Riddell (Appointed 24 May 2021, Resigned 31 May 2022) 

Dr Anne Brindley (Resigned 16 December 2021) 

Company Secretary 

Mr Ben Harber  

Registered Office 

6th Floor 

60 Gracechurch Street, London 

EC3V 0HR 

Auditors 

Jeffreys Henry Audit Limited 

Brokers  

Registrars 

Finsgate 

5-7 Cranwood Street 

London 

EC1V 9EE  

Stanford Capital  

Finsgate 

5-7 Cranwood Street 

London 

EC1V 9EE 

Link Group 

10th Floor 

Central Square 

29 Wellington Street, Leeds 

LS1 4DL 

 
 
 
 
 
 
 
 
 
 
 
3 

Overview 

About Nuformix 

Nuformix plc (“Nuformix” or the “Company”) and its subsidiary (together the “Group”) is a pharmaceutical 
development group targeting unmet medical needs in fibrosis and oncology via drug repurposing. The 
Group aims to use its expertise in discovering, developing and patenting novel drug forms with improved 
physical properties, to develop new products in new indications that are differentiated from the original 
product (by way of dose, delivery route or presentation), thus creating new and attractive commercial 
opportunities. Nuformix has an early-stage pipeline of preclinical assets with potential for significant value 
and early licensing opportunities. 

 
 
 
 
 
 
 
4 

Non-Executive Directors’ Statement 

Dear Shareholder, 

Introduction 

Following the departure of Dr Anne Brindley as Chief Executive Officer, and post period end, Dr Alastair 
Riddell as Executive Chairman, both to pursue other opportunities, the key priority for the directors 
continues to be to focus on the Company’s early-stage pipeline of preclinical assets and ensure strength in 
the areas of drug development, business development and financial control within the Group. We operate 
a lean structure with the limited Board and bring in specialists and consultants, experts in their field, to 
support the business as required. 

To enhance the Group’s funding position to allow the continued work on the three assets in the pipeline, in 
December 2021, the Company undertook an equity fundraise, together with related sharing agreements, 
with Lanstead Capital Investors L.P. (“Lanstead”), an institutional investor. 

Pipeline 

Nuformix has an early-stage pipeline of preclinical assets in development to address the high unmet 
medical need in fibrosis and oncology. We target solutions using our expertise to discover, develop and file 
patent applications on novel drug forms of existing, marketed drugs, that have improved physical 
properties, with the aim of developing novel products in new indications to bring attractive commercial 
opportunities. Importantly, the commercial opportunity is optimised when the repurposed product is 
differentiated from the original marketed drug by way of either dose, route of administration or 
presentation.  

Drug repurposing is a well-known and successful strategy for enhancing the therapeutic and commercial 
value of marketed drugs, and their development typically brings a greater probability of success compared 
to developing brand new drugs, due to the existing data that has been generated on the marketed drug. 
This existence of data may also result in lower overall development costs and shorter development 
timelines. 

The Group’s business model is to take these assets to key value inflection points before partnering or 
licensing. We conduct our R&D activities through out-sourcing, to enable us to access the different types of 
expertise that are needed for drug R&D and to minimise our operational costs. We have a strong network 
of external contractors, with whom we have had relationships over many years. 

NXP002 (new form of tranilast) – Idiopathic Pulmonary Fibrosis (“IPF”) 

NXP002 is the Group’s pre-clinical lead asset and a potential novel inhaled treatment for IPF and possibly 
other fibrosing interstitial lung diseases (“ILDs”). It is a proprietary, new form of the drug tranilast, to be 
delivered in an inhaled formulation.  

Idiopathic Pulmonary Fibrosis (“IPF”) is a devastating lung disease associated with a higher mortality rate 
than many cancers and where there is a need for additional treatment options. Thus, IPF represents a high 
unmet medical need and a significant commercial opportunity. IPF is classified as a rare disease and 
presents a global commercial market that is forecast to grow to US$8.8bn by 2027. Sales of standard-of-
care therapies OFEV and Esbriet achieved US$2.5bn and US$1bn respectively in 2021. 

Tranilast has a long history of safe use as an oral drug for allergies, but there is evidence that supports its 
potential in fibrosis, including IPF. NXP002 is differentiated as it is a new form of tranilast that is being 

 
 
 
5 

formulated for delivery direct to the lungs by inhalation, a new route of administration for this drug. The 
inhalation route is a well-known strategy for treatment of lung diseases to yield greater efficacy and reduce 
systemic side-effects compared to oral treatment. Nuformix has two patent families protecting new forms 
of tranilast, some members of which have been granted in major pharmaceutical territories, while others 
are still in prosecution. In addition, in March 2022 a method of use patent application was filed. 

NXP002, as a potential treatment for IPF, is a likely candidate for Orphan Drug Designation which could 
provide additional product protection against potential competitors. The positioning of such an inhaled 
treatment for IPF could be either added to standard of care or administered as a monotherapy. 

The Company has already generated positive preclinical data on NXP002, demonstrating that: 

-  NXP002  can  be  formulated  in  a  simple  and  stable  solution  suitable  for  inhaled  delivery  via 

nebulisation; 

-  NXP002 formulations for nebulisation can be efficiently delivered to the lung; and 

-  NXP002 can dose-dependently regulate the production of mediators relevant to lung fibrosis and 

inflammation following a lipopolysaccharide ("LPS") challenge. 

However, as announced post-period end on 30 May 2022, no conclusions could be drawn from an 
additional study undertaken to investigate the duration of action of NXP002 formulations. Subsequently 
further studies have been initiated to generate a robust pre-clinical data package to support the 
progression of NXP002, both in terms of product development and business development discussions. 

These studies will directly address issues faced in the duration of action studies. Firstly, the Company will 
investigate a new formulation of NXP002 for inhalation, delivered using an alternative method designed to 
ensure consistent and controlled exposure is achieved. Secondly, the Company will explore a new range of 
doses to best optimise efficacy of treatment. The eventual aim of the studies is to confirm the 
formulation’s positive pharmacological profile towards the treatment of lung fibrosis and inflammation 
via inhalation and to assess its duration of action. Data from these inhalation studies will add to the 
Company’s current compelling pre-clinical dataset, to best support the development of NXP002 as a 
treatment for IPF and potentially other poorly treated fibrosing interstitial lung diseases. 

Post-period, two abstracts describing NXP002 were peer-reviewed and accepted for presentation at the 
European Respiratory Society (“ERS”) International Congress 2022 being held in Barcelona on 4-6 
September 2022. 

NXP001 (new form of aprepitant) – Oncology 

NXP001 is a proprietary new form of the drug aprepitant that is currently marketed as a product in the 
oncology supportive care setting (chemotherapy induced nausea and vomiting). On 23 September 2020, 
Nuformix granted an exclusive option to Oxilio Ltd ("Oxilio"), a privately held pharmaceutical development 
company, to license NXP001 globally for oncology indications on terms previously disclosed. The option 
was executed on 13 September 2021. Oxilio is investigating aprepitant for the potential new treatment of 
cancer indications. Oxilio has entered into a service agreement with Quotient Sciences and is conducting 
formulation development of NXP001 to determine whether it can achieve the bioavailability and 
subsequent dosing regimen required for this new indication.  

NXP004 (novel forms of olaparib) – Oncology 

The Group has discovered novel forms of olaparib, a drug currently marketed by AstraZeneca, under the 
Lynparza® brand name. Lynparza® was first approved in December 2014 for the treatment of adults with 
advanced ovarian cancer and deleterious or suspected deleterious germline BRCA mutation. Since then, 

 
 
6 

Lynparza® has secured similar approvals in breast, pancreatic and prostate cancers with further trials on-
going. These approvals have propelled Lynparza® sales to US$2.7bn in 2021 with industry analysts 
forecasting annual sales of US$9.7bn by 2028.  

The Group has filed two patent applications on these novel forms of olaparib with the potential for patent 
life to 2040/2041.  

The  Company  previously  demonstrated  the  enhanced  performance  of  NXP004  cocrystals  compared  to 
olaparib. Subsequently further preformulation studies have allowed the Company to identify lead cocrystals 
from its patent estate to be progressed for further development.  

Post-period,  the  Company  reported  that  it  initiated  a  programme  of  work  to  progress  the  NXP004 
programme in three key areas: 

  Commence the scale-up of lead cocrystal production processes; 
  Directly  compare  in-vitro  dissolution  performance  of  lead  co-crystals  to  the  marketed  Lynparza 

product; and 

  Based on the results from these studies a formulation development programme may be initiated. 
The aims of this work will be to develop prototype formulations that offer the potential to be both 
bioequivalent and ‘bio-better’ versus the Lynparza product.  

This work will direct and support future out-licensing discussions for NXP004. 

Summary and Outlook 

The strategy of the Group is to continue to optimise value from its existing assets while maintaining tight 
control of costs. In particular, the fundraise with Lanstead has enabled the Group to continue to advance 
and exploit the current assets within the portfolio through additional R&D and business development 
activities as set out above.  

At the appropriate time for each asset, the Group plans to conduct business development/licensing 
activities for all its assets using a structured and data-driven approach, with the goal of seeking global 
licensing deals. 

The Chairman last year acknowledged that there had been a series of changes over the years which we also 
experienced in the past year and more recently, however our focus and emphasis is on stability to progress 
the studies and achieve significant value creation to generate a real return for shareholders. 

We would like to thank all stakeholders and in particular our shareholders for their continued support and 
we look forward to the remainder of the year and beyond with confidence that significant value can be 
realised from our portfolio of assets over time. 

Julian Gilbert 
Non-Executive Director  
27th July 2022 

Maddy Kennedy 
Non-Executive Director 
27th July 2022 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
7 

Strategic Report 

Review of the Business 

A review of the year is given in the Non-Executive Directors’ Statement on pages 4 to 6. 

Risks and uncertainties 

The Group’s risk management policy is regularly reviewed and updated in line with the changing needs of 
the business. Risk is inherent in all business. Set out below are certain risk factors which could have an 
impact on the Group’s long-term performance and mitigating factors adopted to alleviate these risks. This 
does not purport to be an exhaustive list of the risks affecting the Group. 

The primary risks identified by the Board are: 

Strategic risks 

  Funding the business 

The biotechnology and pharmaceutical industries are very competitive, with many major players having 
substantial R&D departments with greater resources and financial support. The Group aims to execute 
licensing deals early in the development process in order to generate revenue to support the business. The 
Group’s lead asset is targeted towards IPF, a disease area where there is good precedent for licensing deals 
at early stages of development. Without licensing revenue, reliance falls on raising funds from investors or 
potential M&A opportunities. Failure to generate additional funding from these sources, if required, would 
compromise the Group’s ability to achieve its strategic objectives as set out in the outlook on page 6. There 
is a material uncertainty around achieving early licensing deals and, if needed, raising additional funds. 
However it is the Directors’ reasonable expectation that the Group has adequate resources to continue to 
operate as a going concern for at least twelve months from the date of the approval of the accounts. In 
forming this assessment, the Directors have prepared cashflow forecasts covering the period ending 31 
March 2024 that take into account the likely run rate on overheads and research and development 
expenditure and the prudent expectations of income from out-licensing rights to its programmes. 

The Subscription proceeds from the Lanstead Sharing Agreements pursuant to which the Company is 
entitled to receive back those proceeds on a pro rata monthly basis over a period of 20 months, subject to 
adjustment upwards or downwards each month depending on the Company's share price at the time. The 
Sharing Agreement provides the opportunity for the Company to benefit from positive future share price 
performance. Notwithstanding the Subscription Price of 1.5 pence, shareholders should note that the share 
price of the Company needs to be on average over the 20 months of the Sharing Agreement at or above 
the Benchmark Price of 2 pence per share for the Company to receive at least, or more than, the gross 
Subscription of GBP1.65million. 

  Feasibility of drug candidates 

Pharmaceutical R&D is an inherently risky activity and drug candidates can fail due to a lack of efficacy, lack 
of potency, unsuitable pharmacokinetic properties, unacceptable toxicology profile, poor stability of the 
drug or formulation, poor performance of the drug product, or other technical issues unforeseen at the 
time of candidate selection. This is the main reason that conventional pharmaceutical R&D takes many 
years and billions of dollars to progress a drug from discovery through to an approved medicine. It is 
possible that the drug candidates selected by the Group are found to be non- viable for further  

 
 
 
8 

Strategic Report 

continued 

development although the Group’s model of repurposing and working on known drugs allows us to 
mitigate this risk to a certain extent. 

  Failure to generate and protect our IP 

If our IP rights are not adequately secured or defended against infringement, or conversely become subject 
to infringement claims by others, commercial exploitation could be completely inhibited. The Group 
constantly monitors its patents and is prepared to defend them rigorously. 

By virtue of conducting research on known drugs, competitors may file patent applications on the same 
drugs as the Group, and thus there is a risk of securing new granted patents. There is a delay of up to 18 
months in publishing patent applications and thus it is not always known whether the Group’s inventions 
will be novel. This is mitigated through knowledge and expertise in identifying new IP and promptly filing 
patent applications. 

  Unrealistic goals and timeframes 

The Board has a duty to maintain a realistic view of the chances of success of products, deals and 
partnerships. Should this not be managed accurately and appropriately, the Group and its Board and staff 
risk financial, business and reputational damage, whilst its shareholders become exposed to investment 
risk and uncertainty over the Group’s viability and status. The Board continually reviews expectations and 
communications in the public domain to reduce the risk of misalignment. 

  Reliance on partners 

To progress the development of a drug candidate requires resources, financial and otherwise, that are not 
necessarily available to the Group. The drug candidates that the Group wishes to develop may be of 
interest to third parties capable of providing these resources, so a partnership (e.g., a co-development 
partnership) may provide mutual benefits and mitigate risks for the Group. However, the specific strategic 
focus of a partner may not align totally with the Group’s objectives. Maintaining a balance in a partnership 
is therefore a risk, such as timing, cost sharing, development decisions. Currently the Group is progressing 
two of its three pipeline assets without external co-development partners and thus this risk is currently 
minimised. 

Operational risks 

  Management, employees, consultants and contractors 

With a fully virtual Group operating model with a reliance on consultants and contractors, the Group’s 
ability to manage day to day tasks and its relationships with its customers and suppliers could be 
undermined by failure to recruit key personnel. The Group endeavours to offer attractive remuneration 
and a positive working environment for all people involved in its projects. The Board are incentivised as 
detailed in the Directors’ Remuneration Report. 

 
 
 
 
 
 
 
9 

Strategic Report 

Continued 

  Business development risks in terms of timing and success of deal flow 

Opportunities to generate value from the portfolio have increased, but there is a need to generate further 
data to make the assets as attractive as possible to potential licensees. The Group seeks to extract value 
from its existing pipeline through early licensing deals once sufficient data are generated, to provide 
revenue. Generation of more robust data packages will lead to a greater probability of successful licensing 
discussions.  

  Adapting to the external environment – COVID-19 

The ability of the Group to quickly adapt to external events such as the outbreak of COVID-19 may impact 
the delivery of our strategy. The pandemic could cause further impact to external research. Our primary 
focus remains the safety of our employees. The Group follows Government advice whilst allowing 
employees to work flexibly. The risks are also minimised by the Group’s virtual business model, allowing 
the Board to work remotely and effectively. Close liaison with contractors ensures that Group projects are 
progressed according to agreed timelines and costs. 

Financial risk management 

  Failure to achieve strategic plans or meet targets or expectations 

The Group actively and regularly reviews and manages its capital structure to ensure an optimal capital 
structure and equity holder returns, taking into consideration the future capital requirements of the Group 
and capital efficiency, prevailing and projected profitability, projected operating cash flows, projected 
capital expenditures and projected strategic investment opportunities. Further detail on the Group’s risk 
management policies and procedures are set out in Note 20 of the financial statements. 

 
 
 
 
 
10 

Strategic Report 

Continued 

Financial Highlights  

  Net assets at year-end of £4,737,962 (2021: £5,686,261) which includes £464,095 cash at bank 

(2021: £1,669,780) 

  The Group delivered a loss on ordinary activities (after tax credit) for the year of £1,108,993 (2021: 
loss of £1,253,497) and a loss per share of 0.19p (2021: 0.22p). The reported loss is driven mainly 
by costs related to the further development of pipeline assets 

  Total revenue for the year of £50,000 (2021: £195,550) 

Future outlook 

The Non-Executive Directors’ Statement on pages 4 to 6 gives information on the outlook of the Group. 

Performance 

The following are the key performance indicators (“KPIs”) considered by the Board in assessing the Group’s 
performance against its objectives. These KPIs are: 

Financial KPIs 

The Group is currently at a stage where the Board considers availability of cash to fund the planned R&D 
activities to be the primary KPI. At 31 March 2022 cash balances totalled £464,095 (2021: £1,669,780). The 
Board will consider introducing additional KPIs to monitor the Group’s development as they become 
relevant in the future. 

  Meeting financial targets: 

The Group actively and regularly reviews and manages its capital structure to ensure an optimal capital 
structure and equity holder returns, taking into consideration the future capital requirements of the Group 
and capital efficiency, prevailing and projected profitability, projected operating cash flows, projected 
capital expenditures and projected strategic investment opportunities. Further detail on the Group’s risk 
management policies and procedures are set out in Note 20 of the financial statements. 

  Revenue from collaborative technology licensing agreements: 

During the year, collaborative agreements with third parties entailed providing fee-for-service work and 
applying Nuformix know how to their proprietary products. This has provided Nuformix with limited short-
term revenue streams. 

The future Group strategy is to prioritise its resources on progressing its own portfolio to generate licensing 
revenue. 

 
 
 
 
 
 
 
 
11 

Strategic Report 

Continued 

Non-Financial KPIs 

  Progress of Lead Programmes: 

The Group strategy is to generate revenue streams through applying and further developing its IP to 
produce proprietary product opportunities for short-term development and early out-licensing 
opportunities. Thus, progression of its assets towards licensing is crucial to the business. 

NXP002: During the year the Group prioritised the development of NXP002, its IPF candidate, and 
generated further preclinical data. Post-period, studies are ongoing to provide a more robust data package 
for potential early licensing. In addition, two abstracts describing the NXP002 were peer-reviewed and 
accepted for presentation at the European Respiratory Society (“ERS”). Progression of the planned R&D, 
filing a patent application and peer reviewed acceptance of submitted abstracts are important 
performance indicators. 

NXP001: In the Group signed an exclusive global licensing agreement with Oxilio to license the NXP001 IP 
for oncology indications. Securing the full licensing agreement is an important performance indicator. 

NXP004: During the year, the Group discovered new forms of olaparib, a commercially attractive oncology 
drug, and filed an additional patent application, an important performance indicator.  

  Co-development with third parties: 

Co-development of generic products with third parties, where Nuformix’s knowhow or IP could provide 
extended patent protection is a potential business model although the Group is prioritising its resources on 
progressing its own portfolio to generate licensing revenue. 

Section 172 

The Board considers the interests of the Group’s employees and other stakeholders, including the impact 
of its activities on the community, environment and the Group’s reputation, when making decisions. The 
Board ensures that its decisions offer the best chance to promote the success of the Group as a whole and 
consider the likely and long-term consequences for all stakeholders, particularly (though not exclusively) 
considering the following: 

  How the views and interests of all stakeholders were represented in the boardroom during the 

year. Open and honest discussion at Board level considers the impact on the Group’s stakeholders 
when reviewing items flowing to the Board as part of its activities, whether this is reviewing 
strategy, budget or a business development opportunity 

  Given the size and stage of development of the Group, the Board has not formally adopted a 

mechanism to obtain stakeholder feedback. However, the Group’s Directors can be contacted at 
info@nuformix.com should any stakeholders wish to contact the Group and shareholders may 
contact the Company’s investor relations adviser, IFC Advisory Limited, at nuformix@investor-
focus.co.uk.  

 
 
 
 
 
12 

Strategic Report 

Continued 

  The Group’s strategy and business model detailed in the Non-Executive Directors’ Statement, on 

pages 4 to 6 

  How the Group manages risks, on pages 7 to 9 

  Corporate governance, on pages 14 to 19, including how governance supported the delivery of our 

strategic objectives in this period 

The Strategic Report was approved by the Board on 27th July 2022 and signed on its behalf by: 

Dr Julian Gilbert 

Maddy Kennedy 

Non-Executive Director  

Non-Executive Director 

27th July 2022 

27th July 2022 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
13 

Board of Directors 

Dr Julian Gilbert, Non-Executive Director 

Dr Julian Gilbert, Non-Executive Director, has more than 30 years of commercial and technical experience 
in the pharmaceutical industry gained at a number of companies including Chiroscience, Mundipharma 
International, BTG and GSK. Most recently, Julian was co-founder and CEO of Acacia Pharma Group 
(Acacia), a leading hospital pharmaceuticals company, raising approximately £100 million in private and 
public funding and leading its flotation on Euronext in 2018. Acacia launched its lead product BARHEMSYS®, 
repurposed amisulpride for the management of PONV, in the US in 2020. Prior to this, he was co-founder 
and Commercial Director of Arakis, a specialist pharmaceutical company repurposing known drugs, that 
was sold to Sosei in 2005 for £107 million, having licensed Seebri®/Ultibro® to Novartis. Julian is currently a 
Non-Executive Chairman of Exvastat and River BioMedics and a Non-Executive Director of Monument 
Therapeutics. Julian has a degree in pharmacy and a PhD in pharmaceutics, both from the University of 
Nottingham. 

Committees:  Julian is Chair of the Nomination and Remuneration Committees and a member of the Audit 
Committee. 

Maddy Kennedy, Non-Executive Director 

Maddy Kennedy, FCCA, is an experienced CFO with a background in the life sciences sector in both public 
and private companies with experience in fundraising, financial modelling, M&A and IPO activities. Maddy 
is currently CFO at Arquer Diagnostics, Tetris Pharma and NuroKor, her previous roles include being CFO 
and/or Board Director at MyHealthChecked plc, Ieso Digital Health Ltd, PsiOxus Therapeutics Ltd and Lab21 
Limited and was Finance Director at Alliance Pharma plc, taking it through its IPO. Maddy is an FCCA and 
has a Post Graduate Diploma in Financial Strategy from Said Business School, Oxford. 

Committees: Maddy is Chair of the Audit Committee and a member of the Nomination and Remuneration 
Committees 

 
 
 
 
 
 
14 

Corporate Governance Report 

We are pleased to present the Corporate Governance report for the year ended 31 March 2022. This 
section of the Annual Report provides a description of our corporate governance structure and processes 
whilst setting out their application throughout the year ended 31 March 2022. 

The Board considers that the Group has complied with all of the provisions of the UK Corporate 
Governance Code throughout the year ended 31 March 2022, except as follows: 

  Given that the Company operates with out-sourced consultants or agency workers, the Board does 

not consider it appropriate to adopt the suggested methods on workforce engagement or 
implementing a diversity and inclusion policy as outlined within the UK Corporate Governance Code 
2018. The Board believes that the arrangements in place are effective but will continue to keep this 
under review. 

  Given the changes to Board composition during the year it was felt that a board evaluation would 

not provide added value.  

  Given the size and stage of development of the Company, all non-executive director remuneration 

includes share options.  

The Board considers that the areas of non-compliance are likely to continue for the medium-term. 

Board Leadership and Company Purpose 

The Board is responsible to the Group’s shareholders for the performance, overall strategic direction, 
values and governance of the Group. It provides the leadership necessary to enable the Group’s business 
objectives to be met within the framework of the internal controls detailed in the report. 

The Board currently comprises two Independent Non-Executive Directors, Dr Julian Gilbert and Ms Maddy 
Kennedy. Collectively the Board’s aim is to increase the value of the Group and ensure its guidance and 
governance is enhanced through an appropriate Board structure and experienced executive management. 
Brief biographies of the Directors appear on page 13. 

The Company’s Articles of Association allow the Directors to authorise conflicts of interest and a register 
has been set up to record all actual and potential conflict situations which have been declared. All declared 
conflicts have been approved by the Board. The Group has instituted procedures to ensure that Directors 
outside interests do not give rise to conflicts with its operations and strategy. 

Where there are any conflict of interests, the relevant director does not participate in Board discussions or 
decisions on such matters and minutes relating to such matters are not circulated to those individuals. 

The Board has adopted a schedule of matters reserved to it for approval. These include the approval of 
changes to the issued share capital, any material changes in the nature or scope of the business of the 
Group, any borrowing or raising of money by the Group which would result in the aggregate borrowing of 
the Group exceeding £100,000 and any lending or giving security on behalf of any shareholder or associate 
of any shareholder of the Group. If required the Board may delegate specific responsibilities to a 
subcommittee with defined terms of reference who will then report back to the full Board at a subsequent 
meeting. 

The Board communicates with shareholders via RNS announcements, other appropriate communications 
platforms and where possible responding to email enquiries from shareholders. It has also engaged an 
independent investor relations adviser, IFC Advisory Limited, to assist with shareholder communications. 

 
 
 
15 

Corporate Governance Report 

Continued 

Additionally, the Board uses the AGM as an occasion to communicate with all shareholders who are 
provided with the opportunity to ask questions. At the AGM, the level of proxy votes lodged on each 
resolution is made available, both at the meeting and subsequently on the Group’s website. Each 
substantially separate issue is presented as a separate resolution. The Committee Chairpersons are 
available to answer questions from shareholders. The website also contains general information on the 
Group’s business, its technology, strategy, business model and R&D activities. 

Board meetings 

Seven scheduled Board meetings and three ad-hoc meetings were held during the 2022 financial year. The 
Board currently has six scheduled meetings for the coming financial year. At each scheduled meeting, the 
Board considers a report on current operational, risk, strategic and health and safety matters, as well as a 
financial and human resources report. Papers for each scheduled Board meeting are usually provided 
during the week before the meeting. 

The following were Directors of Nuformix plc during the year. The list below includes the attendance at the 
scheduled meetings during the year. Certain directors were appointed or resigned during the financial year 
and therefore were not eligible to attend all meetings. Figures in brackets denote the maximum number of 
meetings that could have been attended. 

Board 

Audit 
Committee 

Nomination 
Committee 

Remuneration 
Committee 

Meetings held 
Dr Julian Gilbert 
Dr Alastair Riddell1 
Dr Anne Brindley2 
Dr Joanne Holland3 
Ms Maddy Kennedy 
Karl Keegan4 

7 
7 
6 (6) 
5 (5) 
1 (1) 
7 
1 (1) 

3 
3 
2 (3) 
- 
- 
3 
1 (1) 

3 
3 
1 (1) 
- 
1 (1) 
3 
1 (1) 

2 
2 
1 (1) 
- 
- 
2 
1 (1) 

1 – Dr Alastair Riddell was appointed to the Board on 24th May 2021 and resigned on the 31st May 2022 
2- Dr Anne Brindley resigned from the Board on 16th December 2021 
3 - Dr Joanne Holland resigned from the Board on 31st May 2021 
4 – Karl Keegan resigned from the Board on 24th May 2021  

Division of Responsibilities 

The Directors possess a wide range of skills, knowledge and experience relevant to the strategy of the 
Company, including financial, legal, governance, regulatory and industry experience as well as the ability to 
provide constructive challenge to the views and actions of those employed by the Group in meeting agreed 
strategic goals and objectives. 

In the opinion of the Board, all directors are considered to be independent in character and judgement and 
there are no relationships or circumstances that are likely to affect (or could appear to affect) their 
judgement. Dr Julian Gilbert is the Company’s Senior Independent Director. 

 
 
 
 
 
 
16 

Corporate Governance Report 

Continued 

The Board is of the view that those who held office during the 2022 financial year committed sufficient 
time to fulfil their duties as members of the Board. 

There are agreed procedures for the Directors to take independent professional advice, if necessary, at the 
Group’s expense. All Directors have access to the advice and services of the Company Secretary. In 
addition, newly appointed Directors are provided with comprehensive information about the Group as part 
of their induction process. 

The Board has Audit, Remuneration and Nomination committees. During 2020, the Disclosure Committee 
was reconstituted as a sub-committee of the Audit Committee. 

Each Board committee has established terms of reference detailing its responsibilities and powers. These 
are available in the Investors section at www.nuformix.com. 

Composition, Succession and Evaluation 

The Company has established a Nomination Committee comprising of Dr Julian Gilbert as Chairman and Ms 
Maddy Kennedy as a member. The Committee is responsible for assisting the Board in determining the 
composition and make- up of the Board. It is also responsible for periodically reviewing the Board’s 
structure and identifying potential candidates to be appointed as Directors, as the need arises. The 
selection process is, in the Board’s view, both rigorous and transparent in order to ensure that 
appointments are made on merit and against objective criteria set by the Committee. In reviewing 
potential candidates, the Committee considers the benefits of diversity the Board, while ensuring that 
appointments are made based on merit and relevant experience. 

The Nomination Committee meets as required, but at least once each year. The terms of reference for the 
Committee are available at www.nuformix.com. 

The Committee, in consideration of skills and succession planning, looks at the balance, structure and 
composition of the Board and takes into account the future challenges and opportunities facing the Group. 

Each Non-Executive Director is appointed for an initial term of one year. Subject to agreement, satisfactory 
performance and re-election by shareholders, their appointments may be renewed for further terms of 
one year. 

In order to comply with the UK Corporate Governance Code, all Directors will offer themselves for re-
election by shareholders at each AGM. 

While no formal structured continuing professional development programme has been established for the 
non-executive Directors, every effort is made to ensure that they are fully briefed before Board meetings 
on the Group’s business. In addition, they receive updates from time to time from the executive Directors 
on specific topics affecting the Group and from the Company Secretary on recent developments in 
corporate governance and compliance. The Group also arranges Director training, from time to time, on 
Corporate Governance topics and general Director’s responsibilities. Each of the Non-Executive Directors 
independently ensures that they update their skills and knowledge sufficiently to enable them to fulfil their 
duties appropriately. 

 
 
 
17 

Corporate Governance Report 

Continued 

Given the changes to Board composition during the year it was deemed that a board evaluation review 
would not provide added value and the Board has agreed to review the need for a Board evaluation 
periodically. 

Audit, Risk and Internal Control 

In its obligation to establish formal and transparent arrangements for considering risk management and 
internal controls in addition to maintaining an appropriate relationship with the Group’s auditors, the 
Board has established an Audit Committee. This currently comprises Ms Maddy Kennedy as Chair with Dr 
Julian Gilbert as a member. All members of the Committee have been deemed to possess competence 
relevant to the sector in which the Group operates and Maddy Kennedy has recent and relevant financial 
experience. 

The terms of reference for the Committee take into account the requirements of the Code and are 
available at www.nuformix.com. The current composition of the Committee meets the requirement set out 
for smaller companies. A key role of the Committee is to assist the Board with the discharge of its 
responsibilities in relation to the Group’s financial statements in the areas set out below. 

Corporate reporting 

The Committee monitors the integrity of the financial statements of the Group and formal announcements 
relating to the Group’s financial performance, reviewing significant financial reporting judgements 
contained therein. It reviews the draft annual financial statements and half year results statements prior to 
discussion and approval by the Board. It also reviews the external auditor’s detailed reports on these 
statements. 

The Committee then reports to the Board on matters which it believes the Board should consider in 
ensuring the publication of the financial reports provide a fair, balanced and understandable assessment of 
the Group’s position. The Committee also considers the findings reported to it by the external auditor’s 
process. 

The Group has control mechanisms in place for the engagement of the external auditor in the supply of 
non- audit services. These controls ensure that the objectivity and independence of the external auditor is 
monitored and maintained in projects of a non-audit nature. These controls are reviewed annually to 
consider their continued appropriateness and effectiveness. It is, however, acknowledged that, due to their 
detailed understanding of the Group’s business, it may sometimes be necessary or desirable to involve the 
external auditor in non-audit related work to the extent permitted. 

Internal control and risk management 

Risk management and internal controls is a standing agenda item for each Audit Committee meeting. The 
Committee reviews the effectiveness of the internal controls throughout the year and will take any 
necessary actions should any significant failings or weaknesses be identified. Details of the principal risks 
and uncertainties potentially facing the Group can be found in the Strategic Report on pages 7 to 9. 

Given the size and current stage of development of the Group, the Board acknowledges that it is ultimately 
responsible for ensuring the Group’s systems of internal controls and risk management remain effective.  

 
 
 
18 

Corporate Governance Report 

Continued 

The Board continues to assess: 

  Risks 

  Financial performance 

  Governance 

  Performance of the External Auditor 

Remuneration 

The Board has established a Remuneration Committee in order to set formal and transparent procedures 
and policies for development of Directors’ remuneration packages. The role of the Remuneration 
Committee is to determine and agree with the Board the broad policy for the remuneration of executives 
and Senior Managers as designated, as well as for setting the specific remuneration packages, including 
pension rights and any compensation payments of all executive Directors and the Chairman. The Company’s 
remuneration policies and practices are designed to support its long-term strategy and promote the long-term 
sustainable success of the Company. 

The terms of reference for the Committee consider the requirements of the Code and are available at 
www.nuformix.com. 

The Group’s Remuneration Report can be found on pages 19 to 23. 

Financial Reporting 

The Directors have acknowledged, in the Statement of Directors’ Responsibilities set out on pages 25 and 
26, their responsibility for preparing the financial statements of the Group. The external auditor has 
included, in the Independent Auditor’s Report set out from page 27 to 32, a statement about its reporting 
responsibilities. 

The Directors are also responsible for the publication of a half year report for the Group, which provides a 
balanced and fair assessment of the Group’s financial position for the first six months of each accounting 
year. 

Dr Julian Gilbert 

Maddy Kennedy 

Non-Executive Director  

Non-Executive Director 

27th July 2022 

27th July 2022  

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
19 

Remuneration Report  

Remuneration for the year ended 31 March 2022 

The remuneration tables below (which have been subject to audit) set out amounts paid to each Director 
during the financial years ended 31 March 2022 and 31 March 2021: 

Dr Joanne Holland 

Dr Anne Brindley 

TOTAL 

Dr Karl Keegan 

Dr Julian Gilbert 

Ms Maddy Kennedy 

Mr Alastair Riddell 

TOTAL 

Dr Dan Gooding 
Dr Joanne Holland 
Dr Anne Brindley 

TOTAL 

Dr Chris Blackwell 

Dr Karl Keegan 

Dr Julian Gilbert 

Ms Maddy Kennedy 

TOTAL 

2022 

Annual salary /  
fees 
£’000 

Share Based 
Payments 
£’000 

Pension 
contributions 
£’000 

11 

72 

83 

5 

27 

27 

56 

115 

– 

– 

– 

– 

1 

1 

1 

3 

– 

1 

1 

– 

– 

– 

– 

– 

Total 
£’000 

11 

73 

84 

5 

28 

28 

57 

118 

Annual salary/fees 
£’000 

2021 

Share Based 
Payments 
£’000 

Pension 
contributions 
£’000 

Total 
£’000 

*90 
96 
29 

215 

39 

39 

9 

9 

96 

– 
– 
– 

– 

– 
106 
– 

– 
106 

1 
1 
– 

2 

– 
– 
– 

– 

– 

91 
97 
29 

217 

39 

145 

9 

9 

202 

Total 
£’000 

72 

72 

120 

121 

449 
383 

*:included within salary is £20,000 in respect of compensation for loss of office 

Remuneration of CEO since listing: 

Year 

2022 (Anne Brindley) 

2022 total 

2021  

2020 

2019 
2018 

Remuneration 
£’000 
72 

72 

120 

121 

126 
111 

Annual bonus 
£’000 

- 

- 

- 

- 

5 
- 

SBP charge 
£’000 
- 

- 

- 

- 

323 
272 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
20 

Remuneration Report 

Continued 

Non-Executive Directors’ letters of appointment 

The following table provides details of the Non-executive Directors’ letters of appointment: 

Name 

Date of Appointment 

Julian Gilbert 
Maddy Kennedy 
Alastair Riddell 

24 November 2020 
2 December 2020 
24 May 2021 

The Non-executive Directors’ letters of appointment provide for termination by either party by giving the 
other not less than one months’ notice in writing and the Executive Directors’ letters of appointment 
provide for termination by either party by giving the other not less than six months’ notice in writing. Each 
Non-Executive Director is appointed for an initial term of one year. Subject to agreement, satisfactory 
performance and re-election by shareholders, their appointments may be renewed for further terms of 
one year. 

Directors’ interests in shares 

The beneficial interests of the Directors in the ordinary shares of the Company are set out below: 

J Holland* 
A Brindley 

A Riddell 

J Gilbert 

M Kennedy 

K Keegan* 

As at    31 March 
2022 
Number of 
ordinary shares 

37,500,000 
500,000 

750,000 

250,000 

250,000 

250,000 

As at 31 March 
2021  
Number of 
ordinary shares 

37,500,000 

500,000 

- 

250,000 

250,000 

250,000 

* Share options disclosed in directors’ report on page 24 

Except as stated above, the Company is not aware of any other interests of any Director in the ordinary 
share capital of the Company. There are no requirements or guidelines concerning share ownership by 
Directors. 

This report has been approved by the Board. 

Dr Julian Gilbert 

Maddy Kennedy 

Non-Executive Director  

Non-Executive Director 

27th July 2022 

27th July 2022 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
21 

Remuneration Policy 

The Remuneration Policy (the “Policy”) was initially approved by shareholders at the 2018 AGM of the 
Company. The Remuneration Committee is not proposing to make any major changes to the existing Policy 
however in line with industry best practice and the three-year Policy cycle the Company will be seeking 
shareholder approval at this year’s AGM. The effective date of this Policy is the date on which the Policy is 
approved by shareholders. 

The Remuneration Policy is designed to reflect remuneration trends and employment conditions across the 
Group, to support the Group’s business strategy and to help the Group promote and attain its objective of 
long- term success. 

The Remuneration Committee intends the Remuneration Policy to apply for a further two years and will 
undertake an annual review of the policy to ensure the content continues to reflect the Group’s business 
strategy. 

Below is a table summarising the main aspects of the Remuneration Framework. 

Fixed Element and Purpose 

Operation 

Base Salary 

Salary is paid monthly. 

To provide a basic salary 
commensurate with role and 
experience which is comparable 
with that for similar 
pharma/biotech, companies of a 
similar size in the Cambridge 
Region (we use Radford’s recent 
Cambridge Survey as a 
comparator). The quantum of 
salary is also traded off against the 
Group’s financial resources and its 
ability to pay salary for a sustainable 
period. 

Salaries are reviewed annually by 
the Group’s Remuneration 
Committee. 

Factors affecting salary pay are: 

• 

• 

any relevant deductions (the 
Group offers a cycle scheme 
vouchers); and 

attainment of any bonus- 
related pay within a specified 
period in which the salary is 
paid. 

Maximum Potential 
Salary/Opportunity 

There is no maximum salary 
opportunity. 

Performance 
Metrics 

Not applicable. 

Salaries are paid based upon 
business performance and 
individual contributions towards 
this within the financial year. 

Salaries will be paid in accordance 
with the 2017 Radford Report 
which provides a benchmark for pay 
for numerous technical and 
management roles within the 
pharma/biotech and related 
companies in the Cambridge area. 

Pensions 

Our purpose at present is to 
comply with current legislation. 

that 

In  the  future  we  are  looking  to 
provide  a  pension  contribution 
role  and 
commensurate  with 
experience  which  is  comparable 
with 
similar 
pharma/biotech,  companies  of  a 
in  the  Cambridge 
similar  size 
Region  (we  use  Radford’s  recent 
Cambridge Survey as a comparator) 
when  cash  resources  within  the 
business allow it. 

for 

Not applicable. 

Employees are automatically signed 
up to the Group’s pension plan. 

The  contributions  to  a  defined 
contribution plan are in accordance 
with automatic enrolment scheme 
minimum sums effective from 6 April 
2019. 

At present, the maximum employer 
contributions  required by  law  are 
2% (from 6th April 2018 – 5th April 
2020).  However,  this  will  be 
increasing to 3% from 6th April 2020 
where the employee will be subject 
to contributing a minimum of 5%. 

Executives  cannot  receive  a  cash 
equivalent or salary supplement. 

subject 

to 
are 
Contributions 
legislative 
however 
change 
employees  are  not  restricted  in 
their contributions. 

There  are  no  maximum employee 
contributions. 

There are no cash allowances. 

These rules apply to all employees. 

Other Benefits (in cash or kind) 

The  Group  aims  to  provide  a 
broader  benefits  package 
to 
employees. 

Cycle  scheme  vouchers  are 
available to employees. 

Benefits are limited to maximum 
tax-free allowances. 

Not applicable. 

 
 
 
 
 
 
 
22 

Maximum Potential 
Salary/Opportunity 

There is no maximum. 

Remuneration Policy 

Continued 

Variable Element 
and Purpose 

Bonuses 

The Group aims to provide 
an appropriate incentivised 
programme relating to 
individual performance. 

Operation 

The discretionary annual bonus scheme is 
designed to reward contributions made to 
the Group that exceed the expectations of 
the work levels expected and relate to 
commercial events, specifically income 
from intellectual property out-licensing, 
collaborative development programmes or 
fundraising. 

Executive management is currently eligible 
to receive bonus payments in relation to 
commercial transactions relating to the 
licensing of the Group’s patents (1% of 
License Fees received from the out-
licensing of Nuformix patents for a period 
of three years from commencement).  

The Committee determines the annual 
targets and key performance  indicators 
(“KPIs”) and assesses the performance 
against these targets and KPIs. 

Long Term Incentive 
Schemes (“LTIS”) 

The Committee determines awards  under 
LTIS annually. 

There is no maximum. 

Bonus payments 
effectively provide this for 
three years, as  do the option 
agreements, which provide 
this for five years. 

Profit sharing and Specific 
Incentive Remuneration 
Schemes/Arrangements 

There are no current plans 
for profit sharing. 

Share Option Schemes 
and Share Option Plans 

Specific bonus schemes awarded as 
disclosed. 

No maximum. 

Provide employees with 
tax  efficient means to 
benefit as they contribute 
to the growth of the 
Group. 

Performance Metrics 

Bonuses are paid in the 
event of securing License 
fees from the out-licensing 
of Nuformix assets and 
will depend upon the 
financial strength of the 
Group. 

Future metrics to be 
agreed as the Group 
continues to execute its 
Corporate Development 
strategy. 

Bonuses are paid in the 
event of securing License 
Fees from the out-licensing 
of Nuformix  patents. 

Employees must stay with 
the business and be good 
leavers. 

 
 
 
 
 
 
 
 
 
 
23 

Remuneration Policy 

Continued 

Safeguards (i.e. clawback) 

The Committee has implemented a safeguard to ensure the business and remuneration targets are met in 
a sustainable way and performance reflects genuine achievement against those targets and therefore 
represents the delivery of value for shareholders. For each performance measure, the impact of any 
acquisition, divestment, out-licensing event or collaboration will be quantified and adjusted for after the 
event. Any major adjustment in the calculation of performance measures will be disclosed to shareholders 
on vesting. The Chairman of the Audit Committee and other members, who are also members of the  

Remuneration Committee, provide input on the Audit Committee’s review of the Group’s performance and 
oversight of any risk factors relevant to remuneration decisions.  

 
 
 
24 

Directors’ Report 

The Directors present their report and the financial statements for the year ended 31 March 2022. 

Results and Dividends 

The loss for the year, after tax, amounted to £1,108,993 (2021 Loss: £1,253,497). The directors do not 
recommend payment of a dividend (2021: £nil). 

Substantial shareholdings 

As at 25 June 2022 the Company is aware of the following notifiable interests in its voting rights: 

Lanstead Capital Investors LP 
Dr D J Gooding 
Dr J M Holland 
Centre for Process Innovation 

Directors of the Company 

Number of ordinary 
shares 
96,749,798 
37,500,000 
37,500,000 
26,600,000 

Percentage of voting rights 

13.64 
5.29 
5.29 
3.75 

The Directors, who held office during the year, were as follows:  

Dr A Brindley (Resigned 16 December 2021) 
Dr J C Gilbert  
Ms M E Kennedy  
Dr A J Riddell (Appointed 24 May 2021, Resigned 31 May 2022) 
Dr J M Holland (Resigned 31 May 2021) 
Dr K D Keegan (Resigned 24 May 2021) 

Directors’ interests in shares 

The interests in the equity of the Company held by Directors, who were directors during the year, are set 
out below: 

As at 31 March 
2022 
Number of ordinary 
shares 

As at 31 March 
2022 
Number of share 
options and 
warrants 

As at 31 March 
2021 
Number of ordinary 
shares 

As at 31 March 
2021 
Number of share 
options and 
warrants 

37,500,000 

36,860,000 

37,500,000 

36,860,000 

250,000 
500,000 

250,000 

250,000 

750,000 

- 
- 

3,000,000 

3,000,000 

3,000,000 

250,000 
500,000 

250,000 

250,000 

- 

3,000,000 

- 

- 

- 

- 

J Holland 

K Keegan 
A Brindley 

J Gilbert 

M Kennedy 

A Riddell 

 
 
 
 
 
 
 
 
 
25 

Directors’ Report 
continued 

Directors’ and officers’ liability insurance 

The Group has, as permitted by s234 and 235 of the Companies Act 2006, maintained insurance cover on 
behalf of the Directors and Company Secretary, indemnifying them against certain liabilities which may be 
incurred by them in relation to the Group. 

Financial Risk Management 

Details of financial risk management are provided in the Strategic Report and Note 20 to the financial 
statements. 

Events after the reporting date 

Events after the reporting year are described in Note 22 to the financial statements. 

Research and development activities 

Research and development activities for the period are detailed in the Non-Executive Directors’ Statement 
and Strategic Report. 

Business Review and Future Developments 

The review of the operations and future developments are contained in the Non-Executive Directors’ 
Statement and Strategic Report.  The results for the year are set out in the attached financial statements. 

Disclosure of information to the auditor 
Each Director has taken steps that they ought to have taken as a director in order to make themselves 
aware of any relevant audit information and to establish that the Group’s auditor is aware of that 
information. The Directors confirm that there is no relevant information that they know of and of which 
they know the auditor is unaware. 

Statement of Directors’ Responsibilities 

The Directors are responsible for preparing the Annual Report and the financial statements in accordance 
with applicable law and regulations. Company law requires the Directors to prepare financial statements 
for each financial year. The Directors are required by law to prepare the Group and Parent Company 
financial statements in accordance with UK-adopted international accounting standards. Under Company 
law, the Directors must not approve the financial statements unless they are satisfied that they give a true 
and fair view of the state of affairs of the Company and Group and of the profit or loss for that period. In 
preparing the Company and Group’s financial statements, Companies Act 2006 requires that Directors: 

  Select suitable accounting policies and apply them consistently; 

 
 
 
 
 
 
 
 
 
26 

Directors’ Report 
continued 

  Make judgements and accounting estimates that are reasonable and prudent; 

  State whether applicable under UK-adopted international accounting standards, have been 

followed, subject to any material departures disclosed and explained in the financial statements; 
and 

  Prepare the financial statements on the going concern basis unless it is inappropriate to presume 

that the Group will continue in business. 

The Directors are responsible for keeping adequate accounting records that are sufficient to show and 
explain the Group transactions and disclose with reasonable accuracy at any time the financial position of 
the Group and enable them to ensure that the financial statements comply with the Companies Act 2006. 
They are also responsible for safeguarding the assets of the Group and hence for taking reasonable steps 
for the prevention and detection of fraud and other irregularities. 

In the case of each person who was a director at the time of this report was approved: 

  So far as that Director is aware, there is no relevant audit information of which the Group’s auditor 

is unaware; and, 

  That Director has taken all steps that the director ought to have taken as a director to make himself 
aware of any relevant audit information and to establish that the Group’s auditor is aware of that 
information. 

Auditors 

A resolution to reappoint Jeffreys Henry Audit Limited as auditors will be presented to the members at the 
Annual General Meeting in accordance with Section 485(2) of the Companies Act 2006. 

On behalf of the board, 

Dr Julian Gilbert 

Maddy Kennedy 

Non-Executive Director  

Non-Executive Director 

27th July 2022 

27th July 2022 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
27 

Independent Auditor’s Report  
to the Members of Nuformix plc 

Opinion 

We have audited the financial statements of Nuformix plc (‘Parent Company’) and its subsidiary (together 
the ‘Group’) for the year ended 31 March 2022 which comprise the statement of comprehensive income, 
the statements of financial position, the statements of changes in equity, the statements of cash flows and 
notes  to  the  financial  statements,  including  a  summary  of  significant  accounting  policies.  The  financial 
reporting  framework  that  has  been  applied  in  their  preparation  is  applicable  law  and  UK-adopted 
International Accounting Standards. 

In our opinion, the financial statements: 

•  

give a true and fair view of the state of the Group’s and of the Parent Company’s affairs as at 31 March 
2022 and of the loss for the year then ended; 

•   have been properly prepared in accordance with UK-adopted International Accounting Standards; and 

•   have been prepared in accordance with the requirements of the Companies Act 2006. 

Basis for opinion 

We  conducted  our  audit  in  accordance  with  International  Standards  on  Auditing  (UK)  (ISAs  (UK))  and 
applicable  law.  Our  responsibilities  under  those  standards  are  further  described  in  the  Auditor’s 
responsibilities for the audit of the financial statements section of our report. We are independent of the 
Group in accordance with the ethical requirements that are relevant to our audit of the financial statements 
in the UK, including the FRC’s Ethical Standard as applied to listed entities, and we have fulfilled our other 
ethical responsibilities in accordance with these requirements.  

We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our 
opinion. 

Material uncertainty related to going concern 
We draw attention to note 2 in the financial statements, which indicates that the Group and Parent Company 
is not in a position where is it self-financing and will require further funding which has not yet been secured.  
Whilst  management  are  confident  that  such  funding  will  be  achieved  there  is  an  inherent  material 
uncertainty surrounding this.  As stated in note 2, these events or conditions, along with other matters set 
out in note 2, indicate that a material uncertainty exists that may cast significant doubt on the Group and 
Parent Company’s ability to continue as a going concern. Our opinion is not modified in respect of this matter. 

In auditing the financial statements, we have concluded that the Directors’ use of the going concern basis of 
accounting in the preparation of the financial statements is appropriate.  Our evaluation of the Directors’ 
assessment of the Group’s ability to continue to adopt the going concern basis of accounting included, as 
part of our risk assessment, review of the nature of the business of the Group, its business model and related 
risks including where relevant  the impact of the  COVID-19 pandemic, the requirements of the applicable 
financial reporting framework and the system of internal control. We evaluated the Directors’ assessment of 
the  Group’s  ability  to  continue  as  a  going  concern,  including  challenging  the  underlying  data  and  key 
assumptions used to make the assessment, and evaluated the Directors’ plans for future actions in relation 
to their going concern assessment. 

Our responsibilities and the responsibilities of the Directors with respect to going concern are described in 
the relevant sections of this report.   

 
 
 
 
28 

An overview of the scope of our audit 

As part of designing our audit, we determined materiality and assessed the risks of material misstatement in 
the financial statements. In particular, we looked at where  the Directors made subjective judgments, for 
example in respect of significant accounting estimates that involved making assumptions and considering 
future events that are inherently uncertain. As in all of our audits we also addressed the risk of management 
override of internal controls, including evaluating whether there was evidence of bias by the Directors that 
represented a risk of material misstatement due to fraud.  

How we tailored the audit scope  

We tailored the scope of our audit to ensure that we performed enough work to be able to give an opinion 
on  the  financial  statements  as  a  whole,  taking  into  account  the  structure  of  the  Group,  its  accounting 
processes, its internal controls and the industry in which it operates..  

Key audit matters 

Key  audit matters are those matters that, in our professional judgment, were of most  significance  in our 
audit  of  the  financial statements of the  current  period  and  include  the  most  significant  assessed  risks  of 
material misstatement (whether or not due to fraud) we identified, including those which had the greatest 
effect on: the overall audit strategy, the allocation of resources in the audit; and directing the efforts of the 
engagement team. These matters were addressed in the context of our audit of the financial statements as 
a whole, and in forming our opinion thereon, and we do not provide a separate opinion on these matters. 

In addition to the matter described in the material uncertainty related to going concern section above, we 
have determined the matters below to be the key audit matters to be communicated in our report. 

Below is not a complete list of all risks identified by our audit. 

Key Audit Matter 
Impairment of goodwill  

How our audit addressed the Key Audit Matter 
Our key procedures, among others, included: 

 

  assessing  the  appropriateness  of  the  VIU 
calculations  used  by  the  management  to 
estimate recoverable amount of CGU; 
reconciling key input data applied in the VIU 
calculations to reliable supporting evidence; 
and 
challenging  the  reasonableness  of  key 
assumptions  based  on  our  knowledge  and 
understanding of the business and industry. 
  Obtaining  evidence  of  the  commercial  and 
technical feasibility of the patents owned by 
the subsidiary. 

 

At  31  March  2022,  the  Group  had  goodwill  of 
approximately  £4,023,000  (2021:  £4,023,000) 
arising  from  acquisition  of  business  in  prior 
years. 

For  the  purpose  of  assessing  impairment  on 
goodwill  arising  from  business  combination, 
goodwill is allocated to a single cash generating 
units (‘CGU’) and the recoverable amount of the 
CGU was determined with reference to value-in-
use  (the  ‘VIU’)  calculations  using  cash  flow 
projections.  In  carrying  out  the  impairment 
assessment, significant management judgement 
was  used  to  determine  the  key  assumptions 
underlying the VIU calculations. 

We  have  identified  the  above  matter  as  a  key 
audit matter because goodwill is material to the 
Group  and  the  estimation  of  recoverable 
amount of the CGU involved a significant degree 
of  management  judgement  and  therefore  was 
subject to an inherent risk of error. 

 
 
 
 
 
 
29 

How our audit addressed the Key Audit Matter 
We have performed the following audit procedures: 

  Reviewed  management’s  plan  of  future 
operating cashflows of the subsidiary; and 
  obtaining  evidence  of  the  commercial  and 
technical feasibility of the patents owned by 
the subsidiary 

Based on the audit work performed, we are satisfied 
with management’s assertion on the impairment 
charged on the investment in a subsidiary and the 
amount due from a subsidiary on the parent 
company financial statements.   

Key Audit Matter 
Carrying value of investment in subsidiary and 
recoverability  of 
intercompany  balance  – 
parent company financial statements only. 

The Company had investment in a subsidiary of 
£4,023,484, net of impairment of £7,226,516, at 
the year ended 31 March 2022.  

The  amount  due  from  a  subsidiary  was  fully 
impaired at the year ended 31 March 2022. We 
identified  there  was  a  risk  in  relation  to  the 
impairment  on  the  investment  held  within  the 
parent  company  financial  statements 
its 
subsidiary.  

in 

Management’s  assessment  of  the  recoverable 
amount  of  investment  in  a  subsidiary  requires 
estimation and judgement around assumptions 
used,  including  the  cash  flows  to  be  generated 
from the continuing operations of the subsidiary. 
Changes  to assumptions  could  lead  to material 
changes  in  the  estimated  recoverable  amount, 
impacting  the  value  of 
in  the 
subsidiary and impairment charges. 

investment 

Our application of materiality 

The  scope  of  our  audit  was  influenced  by  our  application  of  materiality.  We  set  certain  quantitative 
thresholds  for  materiality.  These,  together  with  qualitative  considerations,  helped  us  to  determine  the 
scope of our audit and the nature, timing and extent of our audit procedures on the individual financial 
statement line items and disclosures and in evaluating the effect of misstatements, both individually and 
in aggregate on the financial statements as a whole.  

Based on our professional judgment, we determined materiality for the financial statements as a whole as 
follows: 

Group financial statements 

Parent Company financial statements 

Overall 
materiality 
How 
we 
determined it 
Rationale 
for 
benchmark 
applied 

£63,000 

£57,000 

5% of net loss  

1% of total assets 

The  group  as  a  whole  is  currently 
focused  on  the  development  of  its 
Intellectual  Property  (IP),  and  as  such 
the  users  of  the  financial  statements 
will  be  most  concerned  with  the 
furthering 
incurred 
expenditure 
these  IP  assets.  As  such,  the  most 
appropriate  basis 
the  group 
materiality is net profit/loss. 

for 

in 

The parent company is principally holding 
subsidiary  investment.  The  users  of  the 
financial 
statements  will  be  most 
concerned  with  the  value  of  investment. 
As  such,  the  most  appropriate  basis  for 
the  parent  company  materiality  is  total 
assets. 

 
 
 
 
 
 
 
 
 
30 

We agreed with the Board of Directors that we would report to them misstatements identified during our 
audit above £3,150 as well as misstatements below those amounts that, in our view, warranted reporting 
for qualitative reasons.  

Other information 

The directors are responsible for the other information. The other information comprises the information 
included in the  annual  report, other than the financial statements and our auditor’s report  thereon. Our 
opinion on the financial statements does not cover the other information and, except to the extent otherwise 
explicitly stated in our report, we do not express any form of assurance conclusion thereon.  

In connection with our audit of the financial statements, our responsibility is to read the other information 
and,  in  doing  so,  consider  whether  the  other  information  is  materially  inconsistent  with  the  financial 
statements or our knowledge obtained in the audit or otherwise appears to be materially misstated. If we 
identify such material inconsistencies or apparent material misstatements, we are required to determine 
whether there is a material misstatement in the financial statements or a material misstatement of the other 
information. If, based on the work we have performed, we conclude that there is a material misstatement 
of this other information, we are required to report that fact. We have nothing to report in this regard. 

Opinions on other matters prescribed by the Companies Act 2006 

In our opinion the part of the directors’ remuneration report to be audited has been properly prepared in 
accordance with the Companies Act 2006. 

In our opinion, based on the work undertaken in the course of the audit: 

•  

•  

the information given in the strategic report and the directors’ report for the financial year for which 
the financial statements are prepared is consistent with the financial statements; and 

the strategic report and the directors’ report have been prepared in accordance with applicable legal 
requirements. 

Matters on which we are required to report by exception 

In the light of the knowledge and understanding of the Group and its environment obtained in the course of 
the audit, we have not identified material misstatements in the strategic report or the directors’ report. 

We have nothing to report in respect of the following matters in relation to which the Companies Act 

2006 requires us to report to you if, in our opinion: 

•  

•  

adequate accounting records have not been kept by the Group, or returns adequate for our audit have 
not been received from branches not visited by us; or 

the  Group  financial  statements  and  the  directors’  remuneration  report  to  be  audited  are  not  in 
agreement with the accounting records and returns; or 

•  

certain disclosures of directors’ remuneration specified by law are not made; or 

•   we have not received all the information and explanations we require for our audit. 

Responsibilities of directors 

As explained more fully in the directors’ responsibilities statement set out on pages 25 and 26, the directors 
are responsible for the preparation of the financial statements and for being satisfied that they give a true 
and fair view, and for such internal control as the directors determine is necessary to enable the preparation 
of financial statements that are free from material misstatement, whether due to fraud or error. 

 
31 

In  preparing  the  financial  statements,  the  directors  are  responsible  for  assessing  the  Group’s  ability  to 
continue as a going concern, disclosing, as applicable, matters related to going concern and using the going 
concern basis of accounting unless the directors either intend to liquidate the Group or to cease operations, 
or have no realistic alternative but to do so. 

Auditor’s responsibilities for the audit of the financial statements 

Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are 
free from material misstatement, whether due to fraud or error, and to issue an auditor’s report that includes 
our opinion. Reasonable assurance is a high level of assurance but is not a guarantee that an audit conducted 
in accordance with ISAs (UK) will always detect a material misstatement when it exists. Misstatements can 
arise  from  fraud  or  error  and  are  considered  material  if,  individually  or  in  the  aggregate,  they  could 
reasonably be expected to influence the economic decisions of users taken on the basis of these financial 
statements. 

Irregularities,  including  fraud,  are  instances  of  non-compliance  with  laws  and  regulations.  We  design 
procedures in line with our responsibilities, outlined above and on the Financial Reporting Council’s website, 
to detect material misstatements in respect of irregularities, including fraud.  

The extent to which our procedures are capable of detecting irregularities, including fraud 

Our  approach  to  identifying  and  assessing  the  risks  of  material  misstatement  in  respect  of  irregularities, 
including fraud and non-compliance with laws and regulations, was as follows: 

• 

the  senior  statutory  auditor  ensured  the  engagement  team  collectively  had  the  appropriate 
competence, capabilities and skills to identify or recognise  non-compliance with applicable laws and 
regulations;  

•  we identified the laws and regulations applicable to the Group through discussions with the Directors, 

and from our commercial knowledge and experience of the biotech sector; 

•  we focused on specific laws and regulations which we considered may have a direct material effect on 
the  financial  statements  or  the  operations  of  the  group,  including  Companies  Act  2006,  taxation 
legislation, data protection, anti-bribery, employment, environmental, health and safety legislation and 
anti-money laundering regulations; 

•  we assessed the extent of compliance with the laws and regulations identified above through making 

• 

enquiries of management and inspecting legal correspondence; and  
identified  laws  and  regulations  were  communicated  within  the  audit  team  regularly  and  the  team 
remained alert to instances of non-compliance throughout the audit. 

We  assessed  the  susceptibility  of  the  group’s  financial  statements  to  material  misstatement,  including 
obtaining an understanding of how fraud might occur, by: 

•  making enquiries of management as to where they considered there was susceptibility to fraud, their 

• 

knowledge of actual, suspected and alleged fraud; 
considering the internal controls in place to mitigate risks of fraud and non-compliance with laws and 
regulations.  

To address the risk of fraud through management bias and override of controls, we: 

• 
• 
• 

• 

performed analytical procedures to identify any unusual or unexpected relationships;  
tested journal entries to identify unusual transactions; 
assessed whether judgements and assumptions made in determining the accounting estimates set out 
in Note 2 of the financial statements were indicative of potential bias; 
investigated the rationale behind significant or unusual transactions. 

 
 
 
 
 
 
 
 
32 

In  response  to  the  risk  of  irregularities  and  non-compliance  with  laws  and  regulations,  we  designed 
procedures which included, but were not limited to: 

• 
• 
• 
• 

agreeing financial statement disclosures to underlying supporting documentation;  
reading the minutes of meetings of those charged with governance; 
enquiring of management as to actual and potential litigation and claims; 
reviewing correspondence with HMRC and the group’s legal advisor. 

There are inherent limitations in our audit procedures described above. The more removed the laws and 
regulations  are  from  financial  transactions,  the  less  likely  it  is  that  we  would  become  aware  of  non-
compliance. Auditing standards also limit the audit procedures required to identify non-compliance with laws 
and regulations to enquiry of the directors and other management and the inspection of regulatory and legal 
correspondence, if any. 

Material misstatements that arise due to fraud can be harder to detect than those that arise from error as 
they may involve deliberate concealment or collusion.  

A  further  description  of  our  responsibilities  for  the  audit  of  the  financial  statements  is  located  on  the 
Financial Reporting Council’s website at: www.frc.org.uk/auditorsresponsibilities. This description forms part 
of our auditor’s report. 

Other matters we are required to address 

We were appointed by the Board of Directors on 1 March 2022 to audit the financial statements for the 
year ended 31 March 2022. Our total uninterrupted period of engagement is 1 year, covering the year 
ended 31 March 2022. 

The non-audit services prohibited by the FRC’s Ethical Standard were not provided to the Group and we 
remain independent of the Group in conducting our audit.   

Our audit opinion is consistent with the additional report to the Board of Directors. 

Use of our report 

This report is made solely to the company's members, as a body, in accordance with Chapter 3 of Part 16 of 
the Companies Act 2006. Our audit work has been undertaken so that we might state to the Group’s members 
those matters we are required to state to them in an Auditor's report and for no other purpose. To the fullest 
extent permitted by law, we do not accept or assume responsibility to anyone other than the Group and the 
Group's members as a body, for our audit work, for this report, or for the opinions we have formed. 

Sanjay Parmar 
(Senior statutory auditor) 

For and on behalf of Jeffreys Henry Audit Limited 
(Statutory Auditor) 
Finsgate 
5-7 Cranwood Street 
London EC1V 9EE 

Date: 27 July 2022 

 
 
 
  
 
 
 
 
 
 
 
 
Consolidated Statement of Comprehensive Income 
for the year-ended 31 March 2022 

Revenue 

Cost of sales 

Gross profit 
Administrative expenses 

Other operating income 

Operating loss 

Finance costs 

Loss before tax 

Income tax credit 

Loss for the year and total comprehensive loss for the year 

Loss per share – basic and diluted 

The above results were derived from continuing operations. 

Note 

3 

4 

5 

6 

10 

11 

33 

31 March 
2022 
£ 
50,000 

31 March 
2021 
£ 
195,550 

(1,695) 

(62,307) 

48,305 

133,243 

(1,318,577)  (1,507,221) 
1,300 
- 

(1,270,272)  (1,372,678) 

- 

(3,054) 

(1,270,272)  (1,375,732) 

161,279 

122,235 

(1,108,993)  (1,253,497) 

(0.19)p 

(0.22)p 

The accompanying notes to the financial statements on pages 37 to 64 form an integral part of the financial 
statements. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Consolidated Statement of Financial Position  
As at 31 March 2022 

Registration number: 09632100 

Assets 
Non-current assets 
Property, plant and equipment 
Intangible assets 

Current assets 
Trade and other receivables 
Income tax asset 
Cash and cash equivalents 

Total assets 

Equity and liabilities 
Equity 
Share capital 
Share premium 
Merger relief reserve 
Reverse acquisition reserve 
Share option reserve 
Retained earnings 

Total equity 

Current liabilities 
Trade and other payables 

Total equity and liabilities 

Note 

12 
13 

14 

15 

16 

19 

34 

31 March 
2021 
£ 

957 
4,186,868 

4,187,825 

  32,260 
121,020 
1,669,780 

1,823,060 

6,010,885 

591,609 
6,384,835 
10,950,000 
(8,005,195) 
2,005,952 
(6,240,940) 

5,686,261 

31 March 
2022 
£ 

438 
4,150,411 

4,150,849 

199,600 
161,279 
464,095 

824,974 

4,975,823 

615,609 
6,500,817 
10,950,000 
(8,005,195) 
2,026,664 
(7,349,933) 

4,737,962 

237,861 

237,861 

324,624 

324,624 

4,975,823 

6,010,885 

These financial statements were approved by the board on 27th July 2022 and signed on its behalf by: 

Maddy Kennedy 
Director 

The accompanying notes to the financial statements on pages 37 to 64 form an integral part of the financial 
statements.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Consolidated Statement of Changes in Equity 
for the year-ended 31 March 2022 

35 

At 1 April 2021 

Loss for the year and total comprehensive 
loss 
Issue of share capital 

Share issue costs 
Share and warrant based payment 

Share capital 
£ 
591,609 

Share premium 
£ 
6,384,835 

– 

– 

24,000 

– 
– 

145,982 

(30,000) 
– 

Merger relief 
reserve 
£ 
10,950,000 

Reverse 
acquisition 
reserve 
£ 
(8,005,195) 

Share option 
reserve 
£ 
2,005,952 

Retained 
earnings 
£ 
(6,240,940) 

Total 
£ 
5,686,261 

– 

– 

– 
– 

– 

– 

– 
– 

– 

– 

– 
20,712 

(1,108,993) 

(1,108,993) 

– 

– 
– 

169,982 

(30,000) 
20,712 

At 31 March 2022 

615,609 

6,500,817 

10,950,000 

(8,005,195) 

2,026,664 

(7,349,933) 

4,737,962 

At 1 April 2020 
Loss for the year and total comprehensive loss 
Issue of share capital 
Share issue costs 
Share and warrant based payment 

At 31 March 2021 

– 
101,464 
– 
– 

591,609 

Share capital 
£ 
490,145 

Share premium 
£ 
4,480,400 

Merger relief 
reserve 
£ 
10,950,000 

Reverse  
acquisition 
reserve 
£ 
(8,005,195) 

– 
2,113,535 
(209,100) 
– 

– 
– 
– 
– 

– 
– 
– 
– 

Share option 
reserve 
£ 
1,814,613 

– 
– 
– 
191,339 

Retained   
earnings 
£ 
(4,987,443) 

(1,253,497) 
– 
– 
– 

Total 
£ 
4,742,520 

(1,253,497) 
2,214,999 
(209,100) 
191,339 

6,384,835 

10,950,000 

(8,005,195) 

2,005,952 

(6,240,940) 

5,686,261 

The accompanying notes to the financial statements on pages 37 to 64 form an integral part of the financial statements. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
36 

Consolidated Statement of Cash Flows 
for the year-ended 31 March 2022 

Cash flows from operating activities 
Loss for the year 
Adjustments to cash flows from non-cash items 
Depreciation and amortisation 
Loss on disposal of plant, property and equipment 
Finance costs 
Income tax credit 
Share and warrant based payment 

Working capital adjustments 
(Increase)/Decrease in trade and other receivables 
(Decrease)/Increase in trade and other payables 

Cash consumed by operations 
Income taxes received 

Net cash used in operating activities 

Cash flows from investing activities 
Acquisitions of property plant and equipment 
Disposals of property plant and equipment 

Net cash from investing activities 

Cash flows from financing activities 
Issue of shares (net of costs) 
Interest paid 
Reduction in other loans 

Net cash from financing activities 

Net increase/(decrease) in cash and cash equivalents 
Cash and cash equivalents at 1 April 

Cash and cash equivalents at 31 March 

Note 

12,13 
12 
6 
10 

14 
19 

10 

12 
12 

6 

31 March 
2022 
£ 

31 March 
2021 
£ 

(1,108,993) 

(1,253,497) 

36,976 
- 
- 
(161,279) 
20,712 

93,052 
6,179 

3,054 
(122,235) 
191,339 

(1,212,584) 

(1,082,108) 

(167,340) 
(86,763) 

(1,466,687) 
121,020 

47,237 
16,099 

(1,018,772) 
173,606 

(1,345,667) 

(845,166) 

- 
- 

- 

139,982 
- 
- 

139,982 

(1,205,685) 
1,669,780 

464,095 

(605) 
44,322 

43,717 

2,005,899 
(3,054) 
(75,388) 

1,927,457 

1,126,008 
543,772 

1,669,780 

  The accompanying notes to the financial statements on pages 37 to 64 form an integral part of the financial  statements 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
37 

Notes to the Consolidated Financial Statements 
for the year-ended 31 March 2022  

1. 

General information 

Nuformix  plc  (“the  Company”)  and  its  subsidiary  (together,  “the  Group”)  operate  in  the  field  of 
pharmaceutical  development  targeting  unmet  medical  needs  in  fibrosis  and  oncology  via  drug 
repurposing. 

The  Company  is  a  public  limited  company  which  is  listed  on  the  Standard  List  of  the  London  Stock 
Exchange, domiciled in the United Kingdom (“the UK”) and incorporated in England and Wales. 

The address of its registered office is 6th Floor, 60 Gracechurch Street, London, EC3V 0HR. 

The company operates in a virtual manner and as such does not have a principal place of business. 

2. 

Summary of Significant Accounting policies  

Basis of preparation 

On 31 December 2020, IFRS as adopted by the European Union at that date was brought into UK law and 
became  UK-adopted  International  Accounting  Standards,  with  future  changes  being  subject  to 
endorsement  by  the  UK  Endorsement  Board.  Nuformix  plc  transitioned  to  UK-adopted  International 
Accounting Standards in its Group and Parent Company financial statements on 1 April 2021. This change 
constitutes a change in accounting framework. However, there is no change on recognition, measurement 
or disclosure in the financial year reported as a result of the change in framework.  

These Group and Parent Company financial statements were prepared in accordance with UK-adopted 
International Accounting Standards and with the requirements of the Companies Act 2006 as applicable 
to companies reporting under those standards. 

The financial statements of the  Group  and Parent Company  have  been prepared on accrual basis  and 
under historical cost convention. The financial statements are presented in Pounds Sterling which is the 
Group’s functional and presentational currency. 

New Standards and Interpretations 

No new standards, amendments or interpretations, effective for the first time for the period beginning 
on or after 1 April 2021 have had a material impact on the Group.  

Standards, amendments and interpretations that are not yet effective and have not been early adopted 
are as follows: 

Standard 
IAS 1 
IAS 1 
IAS 8 
IAS 12 

IFRS 17 

Impact on initial application 
Classification of liabilities as current or non-current 
Disclosure of accounting policies 
Accounting estimates 
Deferred  tax  related  to  assets  and  liabilities  arising 
from a single transaction 
Insurance contracts 

Effective date 
Not earlier than 1 January 2024 
1 January 2023 
1 January 2023 
1 January 2023 

1 January 2023 

The Directors are evaluating the impact of the new and amended standards above. The Directors believe 
that  these  new  and  amended  standards  are  not  expected  to  have  a  material  impact  on  the  financial 
statements of the Group 

 
 
 
38 

Notes to the Consolidated Financial Statements 
for the year-ended 31 March 2022  

Going concern 

The financial statements have been prepared on the going concern basis of preparation which, inter alia, 
is  based  on  the  Directors’  reasonable  expectation  that  the  Group  and  Parent  Company  has  adequate 
resources to continue to operate as a going concern for at least twelve months from the date of approval 
of these financial statements. In forming this assessment, the Directors have prepared cashflow forecasts 
covering the period ending 31 March 2024 that take into account the likely run rate on overheads and 
research  and  development  expenditure  and the estimates  of the  possibilities  of  raising  funds  through 
issues of equity and have considered alternative strategies should projected income be delayed or fail to 
materialise. 

The Group is not in a position for self-financing and will require further funding which has not yet been 
secured.  Whilst the Directors understand the risks and issues around raising further funds through an 
equity raise, this will be carefully considered, as and when appropriate. 

These  circumstances  indicate  the  existence  of  an  inherent  material  uncertainty  which  may  cast  a 
significant doubt on the Group’s and Parent Company's ability to continue as a going concern, when in 
twelve - eighteen months’ time a thorough review of funding will be required.  However, these scenarios 
have already been considered and will continue to be closely monitored by the Directors.  The financial 
statements do not  include any adjustments that would result  if the company or Group was  unable to 
continue as a going concern. 

The Directors have carried out a thorough review of costs and are clear on the development work to be 
completed.  Discretionary  costs  have  been  carefully  reviewed  and  reduced  where  reasonable  to  do so 
while continuing to allow the prudent running of the business. 

After careful consideration, the Directors consider that they have reasonable grounds to believe that the 
Group can be regarded as a going concern and for this reason they continue to adopt the going concern 
basis in preparing the Group’s financial statements. 

Critical Accounting Estimates and Judgements 

The  preparation  of  these  financial  statements  under  UK-adopted  International  Accounting  Standards 
requires the use of estimates and assumptions that affect the reported amounts of assets and liabilities 
at the date of the financial statements and the reported amounts of revenues and expenses during the 
reporting  year.  These  estimates  and  assumptions  are  based  upon  management’s  knowledge  and 
experience of the amounts, events or actions. Actual results may differ from such estimates. 

The critical accounting estimates are considered to relate to the following: 

Intangible assets 

The Group recognises intangible assets in respect of goodwill arising on consolidation. This recognition 
requires  the  use  of  estimates,  judgements  and  assumptions  in  determining  whether  the  goodwill  is 
impaired at each year end. 

 
 
 
 
 
39 

Notes to the Consolidated Financial Statements 
for the year-ended 31 March 2022  

Share options 

The Group’s fair values equity-settled share-based payment transactions using the Black-Scholes model. 
The use of the models involves judgements and estimates including an assessment of whether the shares 
will  vest.  Should  actual  future  outcomes  differ  from  these  assessments  the  amounts  recognised  on  a 
straight-line basis would vary from those currently recognised. 

Basis of consolidation 

The Group’s financial statements consolidate  those of the parent  company and its subsidiary as of 31 
March 2022. Its subsidiary has a reporting date of 31 March. 

All  transactions  and  balances  between  Group  companies  are  eliminated  on  consolidation,  including 
unrealised gains and losses on transactions between Group companies. Where unrealised losses on intra-
group asset sales are reversed on consolidation, the underlying asset is also tested for impairment from 
a Group perspective. Amounts reported in the financial statements of its subsidiary have been adjusted 
where necessary to ensure consistency with the accounting policies adopted by the Group. 

Profit or loss and other comprehensive income of subsidiaries acquired or disposed of during the year are 
recognised from the effective date of acquisition, or up to the effective date of disposal, as applicable. 

Business combinations 

The Group applies the acquisition method in accounting for business combinations. The  consideration 
transferred by the Group to obtain control of a subsidiary is calculated as the sum of the acquisition-date 
fair values of assets transferred, liabilities incurred and the equity interests issued by the Group, which 
includes  the  fair  value  of  any  asset  or  liability  arising  from  a  contingent  consideration  arrangement. 
Acquisition costs are expensed as incurred.  

Assets acquired and liabilities assumed are generally measured at their acquisition-date fair values. 

Revenue recognition 

Revenue comprises the fair value of the consideration received or receivable for the sale of goods and 
provision of services in the ordinary course of the Group’s activities. Revenue is shown net of sales/value 
added tax, returns, rebates and discounts and after eliminating sales within the Group. 

The Group recognises revenue when: 

• 
• 
• 

the amount of revenue can be reliably measured; 
it is probable that future economic benefits will flow to the entity; and, 
specific  criteria  have  been  met  for  each of  the  Group  activities,  such  as the  demonstration of 
milestone achievements in research or acceptance by both parties. 

 
 
 
 
 
 
40 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

Segmental information 

Operating segments are reported in a manner consistent with the internal reporting provided to the chief 
operating  decision-makers.  The  chief  operating  decision-makers,  who  are  responsible  for  allocating 
resources  and assessing performance of the  operating segments, has been identified as the executive 
Board of Directors. 

All  operations  and  information  are  reviewed  together  so  that  at  present  there  is  only  one  reportable 
operating segment. 

In the opinion of the Directors, during the year the Group operated in the single business segment of the 
research and development of pharmaceutical products using technology developed by the Group. 

Taxation 

Taxation comprises current and deferred tax. Current tax is based on taxable profit or loss for the period. 
Taxable profit differs from net profit or loss as reported in the income statement because it excludes items 
of income or expense that are taxable or deductible in other years and it further excludes items that are 
never taxable or deductible. The Group’s current tax asset is calculated using tax rates that have been 
enacted or substantively enacted at the balance sheet date. 

Deferred tax is recognised on differences between the carrying amounts of assets and liabilities in the 
financial information and the corresponding tax bases used in the computation of taxable profit and is 
accounted for using the balance sheet liability method. Deferred tax liabilities are generally recognised 
for  all  taxable  temporary  differences  and  deferred  tax  assets  are  recognised  to  the  extent  that  it  is 
probable  that  taxable  profits  will  be  available  against  which  deductible  temporary  differences  can  be 
utilised.  Such  assets  and  liabilities  are  not  recognised  if  the  temporary  difference  arises  from  initial 
recognition of goodwill or from the  initial recognition (other than in a business combination) of other 
assets and liabilities in a transaction that affects neither the taxable profit nor the accounting profit. 

Deferred  tax  liabilities  are  recognised  for  taxable  temporary  differences  arising  on  investments  in 
subsidiaries and associates, and interests in joint ventures, except where the Company is able to control 
the reversal of the temporary difference and it is probable that the temporary difference will not reverse 
in the foreseeable future. 

The carrying amount of deferred tax assets is reviewed at each balance sheet date and reduced to the 
extent that it is no longer probable that sufficient taxable profits will be available to allow all or part of 
the asset to be recovered. 

Deferred tax is calculated at the tax rates that are expected to apply in the period when the liability is 
settled, or the asset realised. Deferred tax is charged or credited to profit or loss, except when it relates 
to items charged or credited directly to equity, in which case the deferred tax is also dealt with in equity. 

Deferred tax assets and liabilities are offset when there is a legally enforceable right to set off current tax 
assets against current tax liabilities and when they relate to income taxes levied by the same taxation 
authority  and  the  Company  intends  to  settle  its  current  tax  assets  and  liabilities  on  a  net  basis. 

 
 
 
41 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

Property, plant and equipment 

Property, plant and equipment is stated in the statement of financial position at cost, less any subsequent 
accumulated depreciation and subsequent accumulated impairment losses. 

The cost of property, plant  and equipment includes directly attributable  incremental costs  incurred in 
installation. 
their 

acquisition 

and 

Depreciation 

Depreciation is charged to write off the cost of assets over their estimated useful lives, as follows: 

Asset class 

Depreciation method and rate 

Computer equipment 

33.33% straight line 

Goodwill and Intangible assets 

Goodwill arising on the acquisition of an entity represents the excess of the cost of acquisition over the 
Group’s interest in the net fair value of the identifiable assets, liabilities and contingent liabilities of the 
entity  recognised  at  the  date  of  acquisition.  Goodwill  is  initially  recognised  as  an  asset  at  cost  and  is 
subsequently measured at cost less any accumulated impairment losses. Goodwill is held in the currency 
of the acquired entity and revalued to the closing rate at each reporting year date. 

Goodwill is not amortised, but it is tested for impairment annually, or more frequently if events or changes 
in circumstances indicate that it might be impaired and is carried at cost less accumulated impairment 
losses. Gains and losses on the disposal of an entity include the carrying amount of goodwill relating to 
the entity sold. 

Goodwill  is  allocated  to  cash-generating  units  (“CGUs”)  for  the  purpose  of  impairment  testing.  The 
allocation  is  made  to  those  CGUs  or  groups  of  CGUs  that  are  expected  to  benefit  from  the  business 
combination in which the goodwill arose. The Group currently has only one CGU. 

Other  intangible  assets,  including  customer  relationships,  licences,  patents  and  trademarks,  that  are 
acquired by the Group and have finite useful lives are measured at cost less accumulated amortisation 
and any accumulated impairment losses.  

Amortisation is provided on the Group’s patents to write off the cost, less any estimated residual value, 
over their expected useful economic life on a 10% straight line basis. 

 
 
 
 
 
 
 
42 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

Impairment testing of goodwill, other intangible assets and property, plant and equipment 

For impairment assessment purposes, assets are grouped at the lowest levels for which there are largely 
independent  cash  inflows  (cash-generating  units).  As  a  result,  some  assets  are  tested  individually  for 
impairment  and  some  are  tested  at  cash-generating  unit  level.  Goodwill  is  allocated  to  those  cash-
generating  units  that  are  expected  to  benefit  from  synergies  of  a  related  business  combination  and 
represent the lowest level within the Group at which management monitors goodwill.  

Cash-generating units to which goodwill has been allocated (determined by the Group’s management as 
equivalent to  its  operating  segments)  are  tested  for impairment  at  least  annually.  All  other  individual 
assets or cash-generating units are tested for impairment whenever events or changes in circumstances 
indicate that the carrying amount may not be recoverable.  

An impairment loss is recognised for the amount by which the asset’s (or cash-generating unit’s) carrying 
amount exceeds its recoverable amount, which is the higher of fair value less costs of disposal and value-
in-use. To determine the value-in-use, management estimates expected future cash flows from each cash-
generating unit and determines a suitable discount rate in order to calculate the present value of those 
cash  flows.  The  data  used  for  impairment  testing  procedures  are  directly  linked  to  the  Group’s  latest 
approved  budget,  adjusted  as  necessary  to  exclude  the  effects  of  future  reorganisations  and  asset 
enhancements.  Discount  factors  are  determined  individually  for each  cash-generating  unit  and  reflect 
current market assessments of the time value of money and asset-specific risk factors. 

Impairment losses for cash-generating units reduce first the carrying amount of any goodwill allocated to 
that cash-generating unit. Any remaining impairment loss is charged pro rata to the other assets in the 
cash-generating unit.  

Cash and cash equivalents 

Cash and cash equivalents comprise cash on hand and call deposits, and other short-term highly liquid 
investments that are readily convertible to a known amount of cash and are subject to an insignificant risk 
of changes in value. 

Financial instruments 

IFRS 9 requires an entity to address the classification, measurement and recognition of financial assets 
and liabilities. 

i) Classification 

The Company classifies its financial assets in the following measurement categories: 

• 

those to be measured at amortised cost. 

The classification depends on the Company’s business model for managing the financial assets and the 
contractual terms of the cash flows. 

The Company classifies financial assets as at amortised cost only if both of the following criteria are met: 

 
 
 
 
43 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

• 
• 

the asset is held within a business model whose objective is to collect contractual cash flows; and 
the contractual terms give rise to cash flows that are solely payment of principal and interest. 

ii) Recognition 

Purchases  and  sales  of  financial  assets  are  recognised  on  trade  date  (that  is,  the  date  on  which  the 
Company commits to purchase or sell the asset). Financial assets are derecognised when the rights to 
receive cash flows from the financial assets have expired or have been transferred and the Company has 
transferred substantially all the risks and rewards of ownership. 

iii) Measurement 

At initial recognition, the Company measures a financial asset at its fair value plus, in the case of a financial 
asset not at fair value through profit or loss (FVPL), transaction costs that are directly attributable to the 
acquisition of the financial asset.  

Transaction costs of financial assets carried at FVPL are expensed in profit or loss. 

Debt instruments  

Amortised  cost:  Assets  that  are  held  for  collection  of  contractual  cash  flows,  where  those  cash  flows 
represent solely payments of principal and interest, are measured at amortised cost. Interest income from 
these financial assets is included in finance income using the effective interest rate method. Any gain or 
loss arising on derecognition is recognised directly in profit or loss and presented in other gains/(losses) 
together with foreign exchange gains and losses. Impairment losses are presented as a separate line item 
in the statement of profit or loss. 

iv) Impairment 

The Company assesses, on a forward looking basis, the expected credit losses associated with any debt 
instruments carried at amortised cost. The impairment methodology applied depends on whether there 
has been a significant increase in credit risk. For trade receivables, the Company applies the simplified 
approach  permitted  by  IFRS  9,  which  requires  expected  lifetime  losses  to  be  recognised  from  initial 
recognition of the receivables. 

Financial liabilities 

The Group’s financial liabilities include other payables. 

Financial  liabilities  are  initially measured  at  fair value,  and,  where  applicable,  adjusted  for  transaction 
costs unless the Group designated a financial liability at fair value through profit or loss. 

Subsequently,  financial  liabilities  are  measured  at  amortised  cost  using  the  effective  interest  method 
except for derivatives and financial liabilities designated at FVTPL, which are carried subsequently at fair 
value with gains or losses recognised in profit or loss (other than derivative financial instruments that are 
designated and effective as hedging instruments). 

All interest-related charges and, if applicable, changes in an instrument’s fair value that are reported in 
profit or loss are included within finance costs or finance income. 

 
 
 
 
44 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

Equity 

Equity comprises the following: 

• 

• 

• 

• 

• 

• 

“Share capital” represents the nominal value of equity shares. 

“Share premium” represents the amount paid for equity shares over the nominal value. 

“Reverse acquisition reserve” arises due to the elimination of the Company’s investment in 
Nuformix Technologies Limited. 

“Merger relief reserve” represents the share premium arising on issue of shares in respect of 
the reverse acquisition takeover. 

“Share option reserve” represents the fair value of options issued. 

“Retained earnings” represents retained earnings/losses. 

Defined contribution pension obligation 

A defined contribution plan is a pension plan under which fixed contributions are paid into a separate 
entity and has no legal or constructive obligations to pay further contributions if the fund does not hold 
sufficient assets to pay all employees the benefits relating to employee service in the current and prior 
years. 

For defined contribution plans contributions are paid into publicly or privately administered pension 
insurance plans on a mandatory or contractual basis. The contributions are recognised as employee 
benefit expense when they are due. If contribution payments exceed the contribution due for service, 
the excess is recognised as an asset. 

Share based payments 

Equity-settled share-based payments to employees and others providing similar services are measured 
at the fair value of the equity instruments at the grant date. The fair value excludes the effect of non-
market-based vesting conditions. Details regarding the determination of the fair value of equity-settled 
share-based transactions are set out in note 17. 

The fair value determined at the grant date of the equity-settled share-based payments is expensed on a 
straight-line basis over the vesting period, based on the Group’s estimate of the number of equity 
instruments that will eventually vest. At each reporting date, the Group revises its estimate of the 
number of equity instruments expected to vest as a result of the effect of non-market-based vesting 
conditions. The impact of the revision of the original estimates, if any, is recognised in profit or loss such 
that the cumulative expense reflects the revised estimate, with a corresponding adjustment to reserves. 

 
 
 
 
 
 
 
 
 
 
45 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

Equity‑settled share‑based payment transactions with parties other than employees are measured at 
the fair value of the goods or services received, except where that fair value cannot be estimated 
reliably, in which case they are measured at the fair value of the equity instruments granted, measured 
at the date the entity obtains the goods or the counterparty renders the service. 

For cash‑settled share‑based payments, a liability is recognised for the goods or services acquired, 
measured initially at the fair value of the liability. At each reporting date until the liability is settled, and 
at the date of settlement, the fair value of the liability is remeasured, with any changes in fair value 
recognised in profit or loss for the year. 

Earnings per Ordinary Share 

The Company presents basic and diluted earnings per share data for its Ordinary Shares.  

Basic earnings per Ordinary Share is calculated by dividing the profit or loss attributable to Shareholders 
by the weighted average number of Ordinary Shares outstanding during the period.  

Diluted earnings per Ordinary Share is calculated by adjusting the earnings and number of Ordinary 
Shares for the effects of dilutive potential Ordinary Shares 

Investment in subsidiaries 

Investments in subsidiaries are carried in the Company’s balance sheet at cost less accumulated 
impairment losses. On disposal of investments in subsidiaries the difference between disposal proceeds 
and the carrying amounts of the investments are recognised in profit or loss. 

3. 

Revenue 

The analysis of the Group’s revenue for the year from continuing operations is as follows: 

Rendering of services 

Licensing Fees 

2022 
£ 

2021 
£ 

- 

145,550 

50,000 

50,000 

50,000 

195,550 

 
 
 
 
 
 
 
 
 
 
 
 
Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

Other operating income 

4. 
The analysis of the Group’s other operating income for the year is as follows:   

Miscellaneous other operating income 

5. 

Operating loss 

Arrived at after charging 

Depreciation expense (including lease depreciation) 
Amortisation expense 
Loss on disposal of tangible fixed assets 
Research and development expenditure 
Share option and warrant charge 

Details of the share-based payments can be found in Note 17. 

6. 

Finance income and costs 

Finance costs 

Interest on lease liabilities 

Total finance costs 

46 

2022 
£ 

- 

2021 
£ 

1,300 

2022 
£ 
519  
36,457  
-  
572,921  
20,712  

2021 
£ 
32,058  
60,994  
6,179  
362,878  
191,399  

2022 
£ 

2021 
£ 

- 

- 

3,054 

3,054 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
47 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

7. 

Staff costs 

The aggregate payroll costs (including directors’ remuneration) were as 
follows: 

Wages and salaries 
Social security costs 
Pension costs, defined contribution scheme 

2022 
£ 
197,983  
18,533  
1,721  
218,237  

2021 
£ 
388,594  
36,404  
3,870  
428,868  

The average number of persons employed by the Group (including directors) during the year and 
analysed by category was as follows: 

Research and development 

Non-executive directors 

Total 

8. 

Directors’ remuneration 

The Directors’ remuneration for the year was as follows:  

Remuneration 

Share based payment charge 

2022 
No. 
2 

2 

4 

2021 
No. 
3 

2 

5 

2022 
£ 

197,983 

3,895 

201,878 

2021 
£ 

311,096 

105,803 

416,899 

Further information about the remuneration of individual directors are provided in the Directors’ 
Remuneration Report. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
48 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

During the year, the number of Directors who were receiving pension benefits was as follows: 

Accruing benefits under money purchase pension scheme 

2022 
No. 

2 

2021 
No. 

2 

Details of the total remuneration paid for the services of the directors are set out on pages 19 to 23 in 

the Remuneration Report. 

In respect of the highest paid director: 

Remuneration 

9 .  

Auditors’ remuneration 

Audit of the financial statements – Group 
Audit of the financial statements – Company 
Audit related assurance service 

 Income tax 

10. 
Tax (credited) in the income statement 

Current taxation 
UK corporation tax 
Adjustment in respect of prior years 

2022 
£ 

72,143 

2022 
£ 
34,000 
19,000 
- 

2021 
£ 

97,000 

2021 
£ 
34,000 
19,000 
5,000 

2022 
£ 

2021 
£ 

(161,279) 
- 

(121,020) 
(1,215) 

(161,279) 

(122,235) 

The tax on loss before tax for the year is lower than (2021: lower than) the standard rate of corporation 
tax in the UK of 19%    (2021: 19%). 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
49 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

The differences are reconciled below: 

Loss before tax 

Corporation tax at standard rate 19% 
Excess of depreciation over capital allowances  
Expenses not deductible 
Tax losses for which no deferred tax asset was recognized 
Adjustment in respect of research and development tax credit 
Adjustment in respect of prior years 

Total tax credit 

2022 
£ 

(1,270,272) 

2021 
£ 
(1,375,732) 

(241,352) 
6,932 
3,935 
138,601 
(69,396) 
- 

(261,389) 
7,036 
36,354 
149,052 
(52,073) 
(1,215) 

(161,279) 

(122,235) 

No deferred tax asset has been recognised as the Directors cannot be certain that future profits will be 
sufficient for this asset to be realised.  As at 31 March 2022 the Group has tax losses carried forward of 

approximately £4,853,000 (2021: £4,120,000). 

11. 

Loss per share 

Loss per share is calculated based on the weighted average number of shares outstanding during the 

period. Diluted loss per share is calculated based on the weighted average number of shares outstanding 
and the number of shares issuable as a result of the conversion of dilutive financial instruments. 

Loss after tax 
Weighted average number of shares – basic and diluted 
Basic and diluted loss per share 

2022 
£ 
(1,108,993) 
598,447,724 
(0.19)p 

2021 
£ 
(1,253,497) 
580,629,372 
(0.22)p 

There is no difference between the basic and diluted earnings per share as the effect would be to decrease 
earnings per share.  

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

12. 

Property, plant and equipment 

Cost 
At 1 April 2021 
Additions 
Disposals 

At 31 March 2022 

Depreciation 
At 1 April 2021 
Charge for the year 
Eliminated on disposal 

At 31 March 2022 

Carrying amount 
At 31 March 2022 

At 31 March 2021 

50 

Total 
£ 

1,561 
- 
- 
1,561 

604 
519 
- 

Computer 
equipment 

£ 

1,561 
- 
- 
1,561 

604 
519 
- 

1,123 

1,123 

438 

957 

438 

957 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
51 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

13. 

  Intangible assets 

Cost 
At 1 April 2021 
Additions 

Written-off 

At 31 March 2022 

Amortisation 
At 1 April 2021 
Amortisation charge 

On written-off 

At 31 March 2022 

Net book value 
At 31 March 2022 

At 31 March 2021 

Goodwill 
£ 

4,023,484  
–  
-  
4,023,484  

–  
–  
-  
–  

Patents 
£ 

449,611  
–  
(85,035)  
364,576  

286,227  
36,457  
(85,035)  
237,649  

Total 
£ 

4,473,095  
–  
(85,035)  
4,388,060  

286,227  
36,457  
(85,035)  
237,649  

4,023,484  
4,023,484  

126,927  
163,384  

4,150,411  
4,186,868  

For impairment testing purposes, management considers the operations of the Group to represent a 
single  cash generating unit (CGU) focused on pharmaceutical development, targeting unmet medical needs in 

fibrosis and oncology via drug repurposing. The directors have assessed the recoverable amount of goodwill, 

which in accordance with IAS36 is the higher of its value in use and its fair value less cost to sell (fair value), in 
determining whether there is evidence of impairment. 

As at 31 March 2022, the Group assessed the recoverable amount of the CGU with reference to a value-
in-use  calculation  based  on  cash  flow  projection  of  the  subsidiary.  The  calculations  uses  cash  flow 

projection based on financial budgets approved by the Directors covering a 30-year period with discount 
rate  of  15%  assumed.  The  recoverable  amount  of  the  CGU  based  on  the  value-in-use  calculation 

exceeded its carrying amount. The Directors also assessed the market capitalisation of the Group with 
reference to the share price of the Company and supported the view that goodwill is not impaired. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

14. 

Trade and other receivables 

Prepayments 
Other receivables 

52 

31 March   
2022 
£ 

27,941   
171,659   
199,600   

31 March 
2021 
£ 
14,742  
17,518  
32,260  

The fair value of trade and other receivables is considered by the Directors not to be materially different 
to the carrying amounts.  

15. 

  Cash and cash equivalents 

Cash at bank 

31 March 
2022 
£ 

31 March 
2021 
£ 

464,095 

1,669,780 

The Directors consider that the carrying value of cash and cash equivalents represents their fair value. 

16. 

Share capital 

Allotted, called up and fully paid shares 

31 
March 
2022 

No. 

Ordinary shares of £0.001 each 

615,609,368 

As at 1 April 2021 
Placement of new shares on the stock market 

As at 31 March 2022 

31 
March 
2021 

£  
615,609  

No. 

£ 

591,609,368 

591,609 

No. 
591,609,366  
24,000,000  
615,609,368  

On 17 December 2021, the company completed a capital increase through the issue of 24,000,000 
shares of £0.001 each in a share placement at a price of £0.015 per share, with a share premium of 
£115,982. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
53 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

17. 

  Share options and warrants 

The Group operates share-based payment arrangements to remunerate Directors and key employees in 
the form  of  a  share  option  scheme.  Equity-settled  share-based  payments  are  measured  at  fair  value 
(excluding  the effect  of  non-market  based  vesting  conditions)  at  the  date  of  grant.  The  fair  value  is 
determined at the grant date of the equity-settled share-based payments and is expensed on a straight-
line basis over the vesting period, based on the Group’s estimate of shares that will eventually vest and 
adjusted for the effect of non- market based vesting conditions. 

The following share-based payments were made in the year to 31 March 2022: 

On 31 January 2022, the directors, A. Riddell. J. Gilbert and M. Kennedy were granted warrants to 

subscribe for 3,000,000 new Ordinary shares  of £0.001 at an exercise price of 1.45p each. The 
warrants are exercisable up until 31 January 2023. The fair value of the warrants was determined 

using the Black-Scholes option pricing model at 1.45p per warrant. 

The  fair  value  of  the  options  and  warrants  issued  in  2022  were  determined  using  the  Black-Scholes 

option pricing model, where appropriate, and had a weighted average of 2.46p per option (2021: 2.46p). 

The  significant  inputs  into  the  model  in  respect  of  the  options  and  warrants  granted  in  the  years 
ended  31 March 2021 and 31 March 2022 were as follows: 

Grant date share price 
Exercise price 
No. of share options 
Risk free rate 
Expected volatility 
Expected option life 

2022 
Existing director 
warrants 

1.45-4.15p 
1.45-2.80p 
13,746,943 
0.153-0.44% 
50-97% 
1-5 years 

2021 
Existing 
 director 
warrants 
2.5-4.15p 
2.8p 
1,160,713 
0.44% 
95% 
5 years 

 
 
 
 
 
 
 
Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

The following table sets out details of the granted warrants and options movements: 

Number of 
warrants/ 
options at 1 
April 2020 

36,860,000  
3,000,000  
- 
- 
- 

1,625,000  
36,860,000  
3,000,000  

- 
- 
- 
- 
- 

- 
- 
- 

Issued in 
year 

Lapsed in 
year 

Number of 
warrants / 
options at 31 
March 2021 

Issued in 
year 

Lapsed in 
year 

- 
- 
- 
- 
- 

36,860,000  
3,000,000  
- 
- 
- 

- 
- 
3,000,000  
3,000,000  
3,000,000  

- 
(3,000,000) 
- 
- 
- 

Number of 
warrants/ 
options at 31 
March 2022 

36,860,000  
- 
3,000,000  
3,000,000  
3,000,000  

(1,625,000) 

- 
- 

0  
36,860,000  
3,000,000  

- 
- 
- 

- 
- 
(3,000,000) 

- 
36,860,000  
- 

Warrant/ option holder 

Directors during year 
J Holland 
K Keegan 
J Gilbert 
M Kennedy 
A Riddell 

Previous directors 
Pascal Hughes 
D Gooding 
C Blackwell 

Other warrants/options 
Novum Securities Limited 
Other warrants 
Alex Eberlin 

- 

- 
81,345,000  

580,357  
580,356  
586,229  
1,746,942  

- 
- 
- 
(1,625,000) 

580,357  
580,356  
586,229  
81,466,942  

- 
- 
- 
9,000,000  

- 
- 
- 
(6,000,000) 

580,357  
580,356  
586,229  
84,466,942  

2.8p 
2.8p 
4.691p 

21/10/2025 
21/10/2025 
18/12/2023 

54 

Exercise 
price 

Expiry date 

4-10p 
6.75p 
1.45p 
1.45p 
1.45p 

4p 
4-10p 
4p 

16/10/2022 
10/05/2021 
31/01/2023 
31/01/2023 
31/01/2023 

16/10/2020 
16/10/2022 
10/05/2021 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
55 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

18. 

Pension and other schemes 

Defined contribution pension sheme 

The Group operates a defined contribution pension scheme. The pension cost charge for the year 
represents   contributions payable by the Group to the scheme and amounted to £1,721 (2021: £3,870). 

Contributions totaling £Nil (2021: £292) were payable to the scheme at the end of the year and are  

included in creditors. 

19. 

Trade and other payables 

Trade payables 
Accrued expenses 
Social security and other taxes 
Outstanding defined contribution pension costs 
Other payables 

31 March   
2022   

12,351   
218,202   
7,308   
-   
-   

237,861 

31 March  
2021 
£ 
98,955  
197,436  
2,941  
292  
-  
299,624  

The fair value of trade and other payables is considered by the Directors not to be materially different 

to the carrying amounts. All payables are due within one year. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
56 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

20. 

Financial instruments 

Credit risk 

The  main  credit  risk  relates  to  liquid  funds  held  at  banks.  The  credit  risk  in  respect  of  these  bank 
balances is limited because the  counterparties  are  banks  with  high  credit  ratings  assigned  by 

international credit rating agencies. 

Liquidity risk 

The Group seeks to manage financial risk, to ensure sufficient liquidity is available to meet foreseeable 

needs.      An analysis of trade and other payables is given in note 19. 

Capital risk management 

The Group’s objectives when managing capital are: 

• 

• 

• 

to safeguard the Group’s ability to continue as a going concern, so that it continues to provide 
returns and benefits for shareholders; 

to support the Group’s growth; and 

to provide capital for the purpose of strengthening the Group’s risk management capability. 

The Group actively and regularly reviews and manages its capital structure to ensure an optimal capital 

structure and equity holder returns, taking into consideration the future capital requirements of the 
Group  and  capital  efficiency,  prevailing  and  projected  profitability,  projected  operating  cash  flows, 

projected capital expenditures and projected strategic investment opportunities. Management regards 
total equity as capital and reserves, for capital management purposes. 

21. 

Related party transactions 

All transactions with related parties are conducted on an arm’s length basis. 

The remuneration of the key management personnel of the Group, who are defined as the directors, is 

set out  in the directors’ remuneration report. 

Ultimate controlling party 

The Directors do not consider there to be a single ultimate controlling party. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
57 

Notes to the Consolidated Financial Statements 

for the year-ended 31 March 2022 
continued 

22. 

Post Balance Sheet Events 

In December 2021 the Company entered into a Sharing Agreement with Lanstead Capital Partners LP 
(“Lanstead”), split into two tranches of new shares issued with payments to be received over a 20-month 
period from March 2022 to October 2023. Tranche 1 covers the period March 2022 to June 2022 and 
Tranche 2 runs from July 2022 to October 2023 

The agreement is structured in such a way that the proceeds received by the Company are linked to the 
market  price  for the  Company's  shares.  The  proceeds  are  calculated  based  on  the  volume-weighted 
average share price in the month preceding the payment from Lanstead, compared to a target price of 
2p  per  share.  The  total  proceeds  based  on  the  2p  share  price  are  £1,650,000,  with  Tranche  1 
representing £330,000 of this amount. 

At the time of signing the accounts the Company has received the full proceeds from Tranche 1 at a 
value of £139,982 net. This is considered to be an adjusting post balance sheet event and therefore the 
share issue in the year to March 2022 has been adjusted to reflect the known proceeds. 

Tranche 2 of the share issue completed in April 2022 and the proceeds are yet to be determined as they 
relate  to  the  future  share  price.  As  stated  above  this  will  vary  in  accordance  with  the  share's 
performance against the target price of 2p. The issue of shares post year end is considered to be a post 
balance sheet event. 

 
 
 
 
 
 
 
 
 
 
 
 
 
Company Statement of Financial Position 
as at 31 March 2022 

Registration number: 09632100 

Assets 
Non-current assets 
Investment in subsidiary 

Current assets 
Trade and other receivables 
Cash and cash equivalents 

Total assets 

Equity and liabilities 
Equity 
Share capital 
Share premium 
Merger relief reserve 
Share option reserve 
Retained earnings 

Total equity 

Current liabilities 
Trade and other payables 

Total equity and liabilities 

58 

Note 

31 March 
2022 
£ 

31 March 
2021 
£ 

26 

4,023,484 

11,250,000 

4,023,484 

11,250,000 

27 
28 

16 

199,600 
421,027 

   966,461 
1,588,378 

620,627 

2,554,839 

4,644,111 

13,804,839 

615,609 
6,500,817 
10,950,000 
2,026,664 
(15,561,584) 

591,609 
6,384,835 
10,950,000 
2,005,952 
(6,332,753) 

4,531,506 

13,599,643 

29 

112,605 

205,196 

112,605 

205,196 

4,644,111 

13,804,839 

The loss attributable to the Company in the year was £9,228,831 (2021: loss £1,952,281). 

These financial statements were approved by the board on ………………………. and were signed on its 
behalf by:  

Maddy Kennedy 

Director 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
59 

Company Statement of Changes in Equity 

for the year-ended 31 March 2022 

At 1 April 2021 
Loss for the year and total comprehensive income 
Share issued and warrant exercised 
Share and warrant based payment 
Share issue costs 

At 31 March 2022 

At 1 April 2020 
Loss for the year and total comprehensive income 
Share issued and warrant exercised 
Share and warrant based payment 
Share issue costs 

At 31 March 2021 

Share 
capital 
£ 

Share  
premium 
£ 

Merger  
relief 
reserve 
£ 

Share option 
reserve 
£ 

Retained  
earnings 
£ 

Total 
£ 

591,609 

6,384,835 

10,950,000 

  2,005,952 

(6,332,753) 

13,599,643 

– 
24,000 
– 
– 

– 
145,982 
– 
(30,000) 

– 
– 
– 
– 

– 
– 
20,712 
– 

(9,228,831) 
– 
– 
– 

(9,228,831) 
169,982 
20,712 
(30,000) 

615,609 

6,500,817 

10,950,000 

  2,026,664 

  (15,561,584) 

4,531,506 

Share capital 

£ 

490,145 

– 
101,464 
– 
– 

591,609 

Share  
premium 

£ 

Merger  
relief 
reserve 
£ 

Share option 
reserve 

Retained 
earnings 

£ 

£ 

Total 

£ 

4,480,400 

10,950,000 

  1,814,613 

(4,380,472) 

13,354,686 

– 
2,113,535 
– 
(209,100) 

– 
– 
– 
– 

– 
– 
191,339 
– 

(1,952,281) 
– 
– 
– 

  (1,952,281) 
2,214,999 
191,339 
(209,100) 

6,384,835 

10,950,000 

  2,005,952 

(6,332,753) 

13,599,643 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Company Statement of Cash Flows 

for the year-ended 31 March 2022 

Cash flows from operating activities 
Loss for the year 
Adjustments to cash flows from non-cash items 
Investment Impairment 
Provision against inter group balance 
Share and warrant based payment 
Equity element of convertible loan note 

Working capital adjustments 
(increase)/decrease in trade and other receivables 
(decrease)/Increase in trade and other payables 
Net cash outflow from operating activities 

Cash flows from investing activities 

Loan to subsidiary 
Loan repayments from subsidiary 
Net cash (used)/generated by investing activities 

Cash flows from financing activities 

Issue of shares (net of costs) 
Interest on convertible loan and exchange gains 
Net cash flows from financing activities 

Net increase in cash and cash equivalents 

Cash and cash equivalents at 1 April 
Cash and cash equivalents at 31 March 

60 

Note 

2022 
£ 

2021 
£ 

(9,228,831) 

(1,952,281) 

7,226,516 
1,696,434 
20,712 
– 
(285,169) 

– 
1,288,000 
191,339 
– 
(472,942) 

27 
29 

(175,209) 
(92,591) 
(552,969) 

11,434 
32,399 
(429,109) 

(754,364) 
– 
(754,364) 

(495,829) 
– 
(495,829) 

139,982 
– 
139,982 

2,005,899 
– 
2,005,899 

(1,167,351) 

1,080,961 

1,588,378 
421,027 

507,417 
1,588,378 

The accompanying notes to the financial statements on pages 61 to 64 form an integral part of the financial statements. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
61 

Notes to the Company Financial Statements 

for the year-ended 31 March 2022 
continued 

23. 

Significant accounting policies 

Basis of preparation 

The separate financial statements of the Company are presented as required by the Companies Act 2006. 
As permitted by that Act, the separate financial statements have been prepared in accordance with UK-
adopted International Accounting Standards. 

The financial statements have been prepared on the historical cost basis. The principal accounting policies 
adopted are the same as those set out in note 2 to the Consolidated Financial Statements. In addition, 
Investments in subsidiaries are stated at cost less, where appropriate, provision for impairment. 

24. 

Loss attributable to shareholders 

Under section 408 of the Companies Act 2006 the Company is exempt from the requirement to present 
its own income statement. The loss attributable to the Company in the year was £9,228,831 (2021: loss 
£1,952,281). 

Staff costs 

25. 
The aggregate payroll costs (including directors’ remuneration) were as follows: 

Wages and salaries 
Social security costs 

2022 
£ 
–  
–  
–  

2021 
£ 
112,135  
11,853  
123,988  

The executive directors are employed by Nuformix Technologies Limited, a wholly owned subsidiary of 
the Company. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
62 

Notes to the Company Financial Statements 

for the year-ended 31 March 2022 
continued 

Investment in subsidiary 

26. 
                                                                                                                                                                                            £ 

At 1 April 2021 
Impairment  
At 31 March 2022 

The Company has the following interests in subsidiaries: 

11,250,000 
(7,226,516) 
4,023,484 

Equity Interest 

Name 

Country of Incorporation 

2022 

2021 

Nuformix Technologies Limited 

United Kingdom 

100% 

100% 

27. 

Trade and other receivables 

Amount owed by Group undertakings 
Prepayments 
Other receivables 

31 March 
2022 
- 
27,941 
171,659 

31 March 
2021 
942,070 
9,786 
14,605 

199,600 

966,461 

The fair value of trade and other receivables is considered by the Directors not to be materially different to 
the carrying amounts. 

28. 

Cash and cash equivalents 

Cash at bank 

31 March 
2022 
£ 

31 March 
2021 
£ 

421,027 

1,588,378 

The Directors consider that the carrying value of cash and cash equivalents represents their fair value. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Notes to the Company Financial Statements 

for the year-ended 31 March 2022 
continued 

29. 

Trade and other payables 

Trade payables 
Accrued expenses 

63 

31 March   
2022 
£ 
8,483   
104,122   
112,605   

31 March 
2021 
£ 
58,054 
147,142 

205,196 

The fair value of trade and other payables is considered by the Directors not to be materially different to 
the carrying amounts. 

30. 

Financial instruments 

Credit risk 

The main credit risk relates to liquid funds held at banks. The credit risk in respect of these bank balances 
is limited because the counterparties are banks with high credit ratings assigned by international credit 
rating agencies. 

Liquidity risk 

The Company seeks to manage financial risk, to ensure sufficient liquidity is available to meet foreseeable 
needs. An analysis of trade and other payables is given in note 30. 

Capital risk management 

The Company’s objectives when managing capital are: 

• 

• 

• 

to safeguard the Company’s ability to continue as a going concern, so that it continues to provide 
returns and benefits for shareholders; 

to support the Company’s growth; and 

to provide capital for the purpose of strengthening the Company’s risk management capability. 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
64 

Notes to the Company Financial Statements 

for the year-ended 31 March 2022 
continued 

The Company actively and regularly reviews and manages its capital structure to ensure an optimal capital 
structure  and  equity  holder  returns,  taking  into  consideration  the  future  capital  requirements  of  the 
Company  and  capital  efficiency,  prevailing  and  projected  profitability,  projected  operating  cash  flows, 
projected  capital  expenditures  and  projected  strategic  investment  opportunities.  Management  regards 
total equity as capital and reserves, for capital management purposes. 

31. 

Related parties 

The Company’s related parties are the directors and other Group companies. 

The remuneration of the key management personnel of the Group, who are defined as the directors, is set 
out in the directors’ remuneration report. Details of the fair value of transactions with key management 
and their close family members is included in note 21. 

All amounts outstanding with related parties are unsecured and will be settled in cash. No guarantees have 
been given or received in respect of amounts outstanding.  In the year a  provision of £2,984,434  (2021: 
£1,288,000)  was  recognised  against  the  balance  due  from  Nuformix  Technologies  Limited.  No  other 
provisions have been made for doubtful debts in respect of amounts owed by other related parties. 

At the balance sheet date, the gross amounts due from other Group companies were as follows: 

Nuformix Technologies Limited 

31 March 
2022 
£ 

31 March 
2021 
£ 

2,984,434 

2,230,070 

 
 
 
 
 
 
 
 
 
 
65 

Notice of Annual General Meeting 

NOTICE IS GIVEN that the Annual General Meeting (the “AGM”) of Nuformix plc (the “Company”) will be held at 6th 
Floor, 60 Gracechurch Street, London, EC3V 0HR  on 25 August 2022 at 2.00pm and if thought fit, pass the following 
resolutions. Resolutions 1 to 7 will be proposed as ordinary resolutions and resolutions 8 to 10 will be proposed as 
special resolutions. 

ORDINARY RESOLUTIONS 

1. 

2. 

3. 

4. 

5. 

6. 

7. 

To  receive  the  Company’s  annual  report  and  accounts  for  the  year  ended  31  March  2022. 

To approve the remuneration report set out on pages 19 to 23 of the annual report for the 
year ended 31 March 2022 

To re-appoint Dr Julian C Gilbert as a director. 

To re-appoint Ms Madeleine E Kennedy as a director. 

To re-appoint Jeffreys Henry Audit Limited as auditor of the Company. 

To authorise the Directors to determine the auditor’s remuneration. 

That, the Directors be generally and unconditionally authorised in accordance with section 551 
of the Companies Act 2006 (the ‘Act’) and in substitution for all existing authorities under that 
section, to exercise all the powers of the Company to allot shares in the Company or to grant 
rights to subscribe for, or to convert any security into, shares in the Company (‘Rights’) up to 
an aggregate nominal amount of £234,072.09  during the period commencing on the date of 
the passing of this resolution and expiring at the conclusion of the next Annual General Meeting 
of the Company or on 30 September 2023, whichever is earlier, and provided further that the 
Company shall be entitled before such expiry to make an offer or agreement which would or 
might require shares to be allotted or Rights to be granted after such expiry and the Directors 
shall  be  entitled  to  allot  shares  and  grant  Rights  under  such  offer  or  agreement  as  if  this 
authority had not expired. 

SPECIAL RESOLUTIONS 

8. 

That, subject to the passing of resolution 7 above, the Directors be empowered under section 
570 of the Act to allot equity securities as defined in section 560 of the Act, as if section 561(1) 
of the Act did not apply to any such allotment, provided that this power shall be limited to the 
allotment or allotments of equity securities up to a nominal amount or (in the case of any other 
equity  securities)  giving  the  right  to  subscribe  for  or  convert  into  relevant  shares  having  a 
nominal amount, not exceeding in aggregate £70,930.94  and this power shall expire, unless 
previously revoked, renewed or varied, at the conclusion of the next Annual General Meeting 
of the Company or on 30 September 2023, whichever is earlier, except that the Company may 
before such expiry make offers or agreements which would or might require equity securities 
to  be  allotted  after  such  expiry  and  the  Directors  may  allot  securities  under  such  offer  or 
agreement as if this power had not expired. 

 
 
 
 
 
 
 
 
 
 
 
 
 
66 

Notice of Annual General Meeting 

continued 

9. 

That the Company be generally and unconditionally authorised for the purposes of section 701 
of  the  Act  to  make  market  purchases  (within  the  meaning  of  section  693(4)  of  the  Act)  of 
in  the  capital  of  the  Company,  provided  that: 
ordinary  shares  of  £0.001  each 

a.  the  maximum  number  of  shares  which  may  be  purchased 

is  106,396,405; 

b.  the  minimum  price  (exclusive  of  expenses)  that  may  be  paid  for  a  share  is  £0.001 

c. 

the maximum price, exclusive of expenses, which may be paid for a share shall be an 
amount equal to 5% above the average market value for the Company’s shares for the 
five business days immediately preceding the day on which the share is contracted to 
be purchased; and 

d.  the authority conferred by this resolution shall, unless previously renewed, expire at 
the end of the next Annual General Meeting of the Company, or on 30 September 2023, 
whichever  is  earlier,  save  that  the  Company  may,  before  such  expiry,  enter  into  a 
contract  for  the  purchase  of  shares  which  would  or  might  be  completed  wholly  or 
partly after such expiry and the Company may purchase shares under any such contract 
as if this authority had not expired. 

10. 

That a general meeting of the Company (other than an annual general meeting) may be called 
on not less than 14 clear days’ notice. 

By Order of the Board 

Ben Harber 

1st August 2022 

Registered Office 

6th Floor 

60 Gracechurch Street 
 London 
 EC3V 0HR 

 
 
 
 
 
 
 
 
 
 
 
 
 
                                                                                       
 
 
67 

Notice of Annual General Meeting 

continued 

Notice of Meeting Notes: 

The following notes explain your general rights as a shareholder and your right to vote at this Meeting or to 
appoint someone else to vote on your behalf. 

1)  To be entitled to vote at the Meeting (and for the purpose of the determination by the Company of the 
number of votes they may cast), shareholders must be registered in the Register of Members of the 
Company at close of trading on 23 August 2022. Changes to the Register of Members after the relevant 
deadline shall be disregarded in determining the rights of any person to vote at the Meeting. 

2)  Shareholders are encouraged to appoint the Chair of the Meeting as their proxy to exercise all or part 
of their rights to vote on their behalf at the Meeting. In the case of joint holders, where more than one 
of the joint holders purports to appoint a proxy, only the appointment submitted by the most senior 
holder will be accepted. Seniority is determined by the order in which the names of the joint holders 
appear in the Company’s Register of Members in respect of the joint holding (the first named being the 
most senior). 

3)  A vote withheld is not a vote in law, which means that the vote will not be counted in the calculation 
of votes for or against the resolution. If no voting indication is given, your proxy will vote or abstain 
from voting at his or her discretion. Your proxy will vote (or abstain from voting) as he or she thinks fit 
in relation to any other matter which is put before the Meeting. 

4) 

You can vote either: 

•  by logging on to www.signalshares.com and following the instructions; 
•  by  downloading  the  new  shareholder  app,  LinkVote+,  on  Apple  App  Store  or  Google  Play  and 

following the instructions; 

•  you may request a hard copy form of proxy directly from the registrars, Link Group, on telephone 
number 0371 664 0300. Calls are charged at the standard geographic rate and will vary by provider. 
Calls outside the United Kingdom will be charged at the applicable international rate. Link Group is 
open between 09:00 – 17:30, Monday to Friday excluding public holidays in England and Wales; 
in  the  case  of  CREST  members,  by  utilising  the  CREST  electronic  proxy  appointment  service  in 
accordance with the procedures set out below. 
In order for a proxy appointment to be valid a form of proxy must be completed. In each case the 
form of proxy must be received by Link Group at Link Group, PXS 1, Central Square, 29 Wellington 
Street, Leeds, LS1 4DL by 2.00pm on 23 August 2022. 

• 

• 

5)  If  you  return more  than  one  proxy  appointment,  either  by  paper  or  electronic  communication,  the 
appointment received last by the Registrar before the latest time for the receipt of proxies will take 
precedence.  You  are  advised  to  read  the  terms  and  conditions  of  use  carefully.  Electronic 
communication  facilities  are  open  to  all  shareholders  and  those  who  use  them  will  not  be 
disadvantaged. 

6)  CREST  members  who  wish  to  appoint  a  proxy  or  proxies  through  the  CREST  electronic  proxy 
appointment  service  may  do  so  for  the  AGM  (and  any  adjournment  of  the  AGM)  by  using  the 
procedures  described  in  the  CREST  Manual  (available  from  www.euroclear.com/site/public/EUI). 
CREST Personal Members or other CREST sponsored members, and those CREST members who  

 
 
 
 
68 

Notice of Annual General Meeting 

continued 

have appointed a service provider(s), should refer to their CREST sponsor or voting service provider(s), 
who will be able to take the appropriate action on their behalf. 

7)  In order for a proxy appointment or instruction made by means of CREST to be valid, the appropriate 
CREST  message  (a  ‘CREST  Proxy  Instruction’)  must  be  properly  authenticated  in  accordance  with 
Euroclear  UK &  Ireland Limited’s  specifications  and must  contain the  information  required  for  such 
instructions, as described in the CREST Manual. The message must be transmitted so as to be received 
by the issuer’s agent (ID RA10) by 2.00pm on 23 August 2022. For this purpose, the time of receipt will 
be  taken to mean the time  (as  determined by the timestamp applied to the message by the  CREST 
application host) from which the issuer’s agent is able to retrieve the message by enquiry to CREST in 
the  manner  prescribed  by  CREST.  After  this  time,  any  change  of  instructions  to  proxies  appointed 
through  other  means. 
through  CREST 

the  appointee 

communicated 

should  be 

to 

8)  CREST members and, where applicable, their CREST sponsors or voting service providers should note 
that  Euroclear  UK  &  Ireland  Limited  does  not  make  available  special  procedures  in  CREST  for  any 
particular message. Normal system timings and limitations will, therefore, apply in relation to the input 
of CREST Proxy Instructions. It is the responsibility of the CREST member concerned to take (or, if the 
CREST member is a CREST personal member, or sponsored member, or has appointed a voting service 
provider(s), to procure that his CREST sponsor or voting service provider(s) take(s)) such action as shall 
be necessary to ensure that a message is transmitted by means of the CREST system by any particular 
time. In this connection, CREST members and, where applicable, their CREST sponsors or voting system 
providers  are  referred,  in  particular,  to  those  sections  of  the  CREST  Manual  concerning  practical 
limitations  of  the  CREST  system  and  timings.  The  Company  may  treat  as  invalid  a  CREST  Proxy 
Instruction  in  the  circumstances  set  out  in  Regulation  35(5)(a)  of  the  Uncertificated  Securities 
Regulations 2001. 

9)  Any corporation which is a shareholder can appoint one or more corporate representatives who may 
exercise  on  its  behalf  all of  its  powers  as  a  shareholder  provided that  no more  than one  corporate 
shares. 
representative 

exercises 

relation 

powers 

same 

the 

to 

in 

10) Under Section 527 of the Companies Act 2006, shareholders meeting the threshold requirements set 
out in that section have the right to require the Company to publish on a website a statement setting 
out any matter relating to: (i) the audit of the Company’s financial statements (including the Auditor’s 
Report  and  the  conduct  of  the  audit)  that  are  to  be  laid  before  the  AGM; or (ii)  any circumstances 
connected with an auditor of the Company ceasing to hold office since the previous meeting at which 
annual financial statements and reports were laid in accordance with Section 437 of the Companies Act 
2006  (in  each  case)  that  the  shareholders  propose  to  raise  at  the  relevant  meeting. 

11) The  Company  may  not  require  the  shareholders requesting  any  such website  publication  to  pay  its 
expenses in complying with Sections 527 or 528 of the Companies Act 2006. Where the Company is 
required  to  place a  statement  on  a  website  under  Section 527 of the  Companies  Act 2006,  it must 
forward the statement to the Company’s auditor not later than the time when it  

 
 
 
 
 
 
 
 
 
69 

Notice of Annual General Meeting 

continued 

makes the statement available on the website. The business which may be dealt with at the AGM for 
the relevant financial year includes any statement that the Company has been required under Section 
527 of the Companies Act 2006 to publish on a website. 

12) You may not use any electronic address (within the meaning of Section 333(4) of the Companies Act 
2006) provided in either this Notice or any related documents (including the form of proxy) to 
communicate with the Company for any purposes other than those expressly stated. 

13) A copy of this Notice, and other information required by Section 311A of the Companies Act 2006, can 

be found on the Company’s website at www.nuformix.com. 

14) At 29th July 2022, (being the latest practicable date prior to the publication of this notice) the issued 
share capital of the Company consisted of 709,309,368 Ordinary Shares of £0.001 each in the capital of 
the Company. Each share carries one vote. The Company held no shares in treasury, therefore the total 
voting rights in the Company as at 29th July 2022 were 709,309,368. 

 
 
 
 
 
 
 
 
70 

Notice of Annual General Meeting 

continued 

EXPLANATION OF BUSINESS 

Resolution 1: To receive the annual report and accounts 

Company law requires the Directors to present the annual report and accounts of the Company to shareholders in 
respect of each financial year. 

Resolution 2: To approve the Remuneration Report 

The Remuneration Report is set out on pages 19 to 23 of the annual financial report. It gives details of the Directors’ 
remuneration for the year ended 31 March 2022. The vote is advisory and does not affect the actual remuneration 
paid to any individual Director. 

Resolutions 3 and 4: To elect Directors 

The Company’s articles of association provide for each director to retire from office at the third annual general meeting 
after the AGM at which he/she was previously appointed or reappointed. However, in line with the recommendations 
set  out  in the UK  Corporate  Governance Code, all Directors will be standing down and offering themselves for re-
election by shareholders at this year’s AGM. Directors’ biographical details are given on page 13 of the annual financial 
report. 

Resolution 5 and 6: To reappoint the auditor and authorise the Board to determine their remuneration 

The Company is required to appoint an auditor at each general meeting at which accounts are laid before the members, 
to hold office until the conclusion of the next such meeting. Resolution 5 is for members to reappoint Jeffreys Henry 
LLP as auditors of the Company and resolution  6 proposes that shareholders authorise the Board to determine the 
remuneration of the auditors. In practice, the audit committee will consider the audit fees and recommend them to 
the Board. 

Resolution 7: Directors’ authority to allot shares 

At the 2021 Annual General Meeting, the Directors were given authority to allot shares in the Company and Resolution 
7 seeks to renew that authority until the conclusion of the next AGM or 30 September 2023, whichever is earlier. The 
resolution would give the Directors authority to allot ordinary shares, and grant rights to subscribe for or convert any 
security into shares in the Company, up to an aggregate nominal value of £234,072.09. This amount represents one-
third of the issued ordinary share capital of the Company as at 29th July 2022, the latest practicable date prior to the 
publication of this document. The Directors have no present intention to allot new shares. 

Resolution 8: Disapplication of pre-emption rights 

If  Directors  of  a  Company  wish  to  allot  shares  in  the  Company,  or  to  sell  treasury  shares,  for  cash  (other  than  in 
connection with an employee share scheme) company law requires that these shares are offered first to shareholders 
in proportion to their existing holdings.  

The purpose of Resolution  8 is to authorise the  Directors  to allot  ordinary shares in the Company, or  sell treasury 
shares, for cash (i) in connection with a rights issue; and, otherwise, (ii) up to a nominal value of £70,930.94, equivalent 
to 10 per cent of the total issued ordinary share capital of the Company as at 29th July 2022 without the shares first 
being offered to existing shareholders in proportion to their holdings. 

 
 
 
 
71 

Resolution 9: Authority to buy back shares 

Under company law, the Company requires authorisation from shareholders if it wishes to purchase its own shares. 
The resolution specifies the maximum number of shares that may be purchased (approximately 15 per cent of the 
Company’s issued share capital) and the highest and lowest prices at which they may be bought. 

If the Company buys back its own shares it may cancel them immediately or hold them in treasury. Treasury shares 
may be sold for cash or cancelled. The Directors believe that it is desirable for the Company to have this choice as it 
will give flexibility in the management of its capital base. 

The Directors have no present intention of exercising this authority but will keep under review the Company’s potential 
to buy back its shares, taking into account other investment and funding opportunities. The authority will only be used 
if in the opinion of the Directors this would be in the best interests of shareholders generally. 

No dividends will be paid on, and no voting rights will be exercised in respect of, treasury shares. 

Resolution 10: Approval for calling of general meetings (other than AGMs) on 14 days’ notice 

Under company law, the Company is required to give 21 clear days’ notice for a general meeting of the Company unless 
shareholders approve a shorter notice period, which cannot be less than 14 clear days (AGMs must continue to be 
held on at least 21 clear days’ notice). 

Resolution 10 proposes a special resolution, and seeks shareholder approval to enable the Company to call general 
meetings, other than AGMs, on at least 14 clear days’ notice. The approval will be effective until the Company’s next 
AGM, when it is intended that a similar resolution will be proposed. The flexibility offered by this resolution will be 
used where, taking into account the circumstances, the Directors consider to be appropriate in relation to the business 
to be considered at the meeting in question and where it is thought to be to the advantage of shareholders as a whole. 
In order to be able to call a general meeting on less than 21 clear days’ notice, the Company must make a means of 
electronic voting available to all shareholders for that meeting. 

Nuformix plc 

6th Floor, 60 Gracechurch Street London EC3V 0HR 

+44(0) 1223 423667 

E: info@nuformix.com