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QRxPharma Limited
Annual Report 2008

QRX · ASX Healthcare
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FY2008 Annual Report · QRxPharma Limited
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FPO See COVER fi le

QRxPHARMA IS A CLINICAL-STAGE SPECIALTY 
PHARMACEUTICAL COMPANY FOCUSED ON THE 
DEVELOPMENT AND COMMERCIALISATION OF 
THERAPIES FOR PAIN MANAGEMENT AND CENTRAL 
NERVOUS SYSTEM (CNS) DISORDERS.

Based on a business strategy to expand the clinical utility and commercial value of 
marketed and/or existing compounds, QRxPharma’s product portfolio includes both late 
and early stage clinical drug candidates with well-defi ned paths to regulatory approval 
and sales. The Company intends to directly commercialise its products in the US and 
seek strategic partnerships as required to accelerate market penetration. QRxPharma’s 
lead compound, Q8003IR, completed initial Phase 3 studies in April 2008, having met 
all primary and secondary endpoints. The Company’s preclinical and clinical pipeline 
includes other technologies in the fi elds of pain management, neurodegenerative 
disease and venomics.

QRxPHARMA LIMITED
ABN 16 102 254 151

CORPORATE DIRECTORY

Directors

Peter C Farrell PhD, ScD, AM, Non Executive Chairman
John W Holaday PhD, Managing Director and Chief Executive Offi cer
R Peter Campbell FCA, FTIA
Gary W Pace PhD
Michael A Quinn MBA

Secretary

Chris J Campbell CA

Notice of annual general meeting

The annual general meeting of QRxPharma Limited will be held on 
4 November 2008 at the Grace Hotel, 77 York Street, Sydney, 
commencing at 10.00 am

Principal registered offi ce in Australia

Share register

Auditor

Solicitors

QRxPharma Limited
Level 1
194 Miller St
North Sydney NSW 2060

Link Market Services Limited
Level 12
680 George Street
Sydney NSW 2000

PricewaterhouseCoopers
Darling Park Tower 2
201 Sussex Street
GPO BOX 2650
Sydney NSW 1171

Dibbs Abbott Stillman
Level 8, Angel Place
123 Pitt Street
Sydney NSW 2000

Stock exchange listings

QRxPharma Limited shares are listed on the Australian Securities Exchange. 
Listing Code: QRX

QRxPharma Limited American Depositary Receipts are listed on the OTCQX.  
Symbol: QRXPY

Website address

www.qrxpharma.com

TABLE OF CONTENTS

Letter from the Chairman 

CEO Review  

  Pain Management 

  Severe Opioid Adverse Events 

  Comparison of Adverse Events 

  Dose-Response Effi cacy 
  Effi cacy: Patient Global Rating 

  Neurodegenerative Diseases 

  Venomics 

Directors’ report 

 2

Auditor’s independence declaration  

4

4

4

5

5
6

7

7

8

Corporate governance statement 

Income statements  

Balance sheets  

Statements of changes in equity  

Cash fl ow statements  
Notes to the fi nancial statements  

Directors’ declaration  

Independent auditor’s report  

Shareholder information  

25

 26

32

33

34

35
36

73

74

77

www.qrxpharma.com  1

 
 
 
 
 
 
 
LETTER FROM THE CHAIRMAN

Dear Shareholders,

Over the past year, QRxPharma has made signifi cant progress, having achieved our projected 
clinical development goals for Q8003IR, the Company’s lead product candidate for the acute 
treatment of moderate to severe pain. Our successful completion of initial Phase 3 studies 
in May 2008 was ahead of schedule, and this accomplishment not only demonstrates the 
Company’s ability to deliver on its development milestones, but also represents the realisation 
of signifi cant steps toward commercialising a fi rst-in-class “dual-opioid®” pain therapy. 

Although opioids such as morphine have been administered to patients to relieve pain for over 
two centuries, these drugs are fraught with severe side effects which often limit their clinical 
use. As preclinical and clinical data demonstrate, our patented dual-opioid® technology – 
a unique, fi xed-ratio morphine and oxycodone product - provides superior pain relief while 
minimising side effects. Our products target both the acute and chronic pain markets (a $12 
billion global market place) and include an immediate release formulation (Q8003IR), a continuous release formulation 
(Q8011CR) and an intravenous formulation (Q8012IV). QRxPharma’s portfolio of dual-opioids® will provide pain physicians 
with diverse doses and formulations that can be tailored to the patient’s needs for more effective pain relief, while minimising 
side effects.

To translate clinical progress into greater shareholder value, we remain focused on commercialising Q8003IR. In mid-2007, 
QRxPharma initiated the manufacturing of 4 capsule strengths for use in clinical trials. In November, 2007, Phase 3 studies 
commenced with the primary objective of determining preferred dose parameters for pain relief in post-surgical patients 
(secondary objectives included patient ratings and side effect profi les). In May 2008, we successfully completed these initial 
Phase 3 studies, having achieved statistical signifi cance for all primary and secondary trial endpoints, including a dose-
related increase in pain relief, with few medically signifi cant side effects. These studies further established a 12mg/8mg 
morphine and oxycodone combination of Q8003IR as the preferred dose for optimal pain relief and tolerability, with rapid 
onset and a duration of action of over six hours.

A year of development activity for Q8003IR concluded with a United States Food and Drug Administration (FDA) meeting 
in July 2008 where we reviewed our clinical data (including effi cacy, safety, side effects and tolerability) as well as assessed 
the suffi ciency of planned clinical trials for New Drug Application (NDA) submission, the fi nal step before commercialisation. 
Pending incorporation of the FDA’s recommended modifi cations, only two additional Phase 3 trials will be required for NDA 
fi ling. Under this streamlined clinical development programme, no additional pharmacology, toxicology or long-term clinical 
safety studies are deemed necessary for regulatory submission. The Company is however considering additional studies to 
generate data that will enhance market entry.

2  QRxPharma  Annual Report 2008

Acceptance of our Q8003IR proposed Phase 3 development plan by the FDA is a measure of success in terms of reduced 
risk, improved resource effi ciencies and de facto endorsement of the potential value of dual-opioids®.  We believe the 
FDA meeting outcome serves to reinforce the soundness of our business strategy – to expand the clinical utility of existing 
compounds as well as deliver new treatments for targeted indications, with well-defi ned paths to regulatory approval, and 
sales to broad specialty markets.

We also continue our close association with both the University of Alabama and the University of Queensland by advancing 
our preclinical pipeline in the areas of neurodegenerative disease and venomics, respectively.

Market conditions have not been favourable to our share price over the past year. Although we have maintained a stable 
base of institutional and retail shareholders during this declining market, there is a clear need to broaden the Company’s 
shareholder base in order to recognise the value of our growing assets. To that end, with JP Morgan, QRxPharma initiated 
an American Depository Receipt programme for US listing, and then recently joined the OTCQX (QRXPY) with the help of 
our Principal American Liaison, Merriman Curhan and Ford. This relationship includes informational road shows, analyst 
coverage and market making, which will afford us broad access to the US market to facilitate US investment in QRxPharma. 

I am proud of what we have accomplished during our fi rst year of public ownership. In the coming year, we will conserve 
cash resources to ensure a strong fi nancial footing and continue our comprehensive clinical trial programme. In addition, 
we plan to extend our intellectual property protection in order to enhance the market value of our product portfolio; we will 
also add global shareholders as well as emphasise business development to establish appropriate strategic partnerships to 
accelerate product commercialisation.

We thank you for your continued support.

Yours sincerely,

Peter C Farrell, PhD, ScD, AM

Chairman

www.qrxpharma.com  3

CEO REVIEW      

Little more than a year ago, QRxPharma had only recently completed its initial public offering (IPO) and listing on the Australian Securities 
Exchange (ASX), full of promise with respect to the Company’s preclinical and clinical pipeline, with emphasis on the fi eld of pain 
management.  We are pleased to report signifi cant progress in the Phase 3 clinical trial programme of our lead compound Q8003IR, 
and the continued progression of other development projects.  This has been achieved whilst still retaining $29.7 million in cash reserves 
at 30 June 2008.

PRODUCT PIPELINE

PRODUCT/PROGRAM

RESEARCH

PRE-CLINICAL

PHASE I

PHASE II

PHASE III

PAIN MANAGMENT

Q8003IR

Q8012IV

Q8011CR

CNS

T9001 (DYSTONIA)

T9001 (PARKINSON’S)

VENOMICS

Q8010

Q8008

PAIN MANAGEMENT

In November 2007, we initiated Phase 3 clinical trials for Q8003IR, the Company’s lead product candidate and most advanced asset, a 
patent-protected dual-opioid® immediate release formulation of morphine and oxycodone for the treatment of moderate to severe acute 
pain. The goal of this double blind, placebo controlled study was to compare four different dosage regimens of Q8003IR in patients with 
moderate to severe post-surgery pain (bunionectomy) and to establish the preferred dose parameters. Secondary endpoints of the study 
included: (i) effi cacy relating to the time to onset of analgesia and the duration of effect and (ii) safety as measured by the incidence and 
intensity of opioid-related adverse events. Completed ahead of schedule in May 2008, the study was conducted with 256 patients at six 
clinical research sites across the United States of America (US).

It is rare that all primary and secondary endpoints are met in Phase 3 studies. QRxPharma achieved this milestone, thus reinforcing the 
potential clinical benefi t and commercial value of its dual-opioid® product portfolio.  Initial Q8003IR Phase 3 effi cacy data demonstrated 
statistically signifi cant analgesic activity at all dose levels, with the 12mg/8mg (morphine-oxycodone) dose delivering the best analgesic 
effect and tolerability profi le.

Although morphine and oxycodone are treatment mainstays for moderate to severe pain, side effects such as nausea, sedation, 
constipation, and respiratory depression limit their use. In our initial Q8003IR Phase 3 studies, very few severe adverse effects were 
observed. In particular, no respiratory depression and minimal somnolence were seen, as well as the absence of euphoria. These were 
unexpected outcomes compared to what is typical with morphine or oxycodone at comparable pain relieving doses following surgery. Such 
data suggests that our dual-opioids® may provide synergistic effects on pain relief with equal or better analgesia at materially lower doses 
than the active opioid comparator while simultaneously reducing the incidence of side effects.

In July 2008, QRxPharma met with the US Food and Drug Administration (FDA) to review proposed Phase 3 protocol designs for the 
remaining trials. Pending incorporation of the FDA’s recommended modifi cations, only two further Phase 3 trials will be required for fi ling of 
a New Drug application (NDA), including a combination rule study in patients experiencing post-surgery (bunionectomy) pain and a placebo 
controlled study in patients following total knee replacement.

4  QRxPharma  Annual Report 2008

Q8003IR DOSE-RESPONSE EFFICACY

***

61.0

51.2

***

48.0

***

**
31.2

1

2

3

4

5

6

7

8

9

10

Q8003IR SEVERE OPIOID ADVERSE EVENTS

Dose (mg)
Phase 3 Study 007

*     p<.05
**     p<.01
***    p<.001

Placebo (N=60)

12/8 mg (N=50)

8
4
D
P
S

I

70

60

50

40

30

20

10

-6.8

0

0

-10

-20

100%

90%

80%

70%

60%

50%

40%

30%

20%

10%

0%

s
t
n
e
i
t
a
P

f

o
%

14.0%

2.0%

0.0%

3.0%

2.0%2.0%

2.0%

0.0% 0.0%

2.0%

2.0%

0.0%

0.0% 0.0%

0.0% 0.0%

0.0% 0.0%

0.0% 0.0%

NAUSEA

EMESIS

DIZZINESS

HEADACHE

PRURITIS

CONSTIPATION

DRY MOUTH

SOMNOLENCE

EUPHORIA

02 DECREASE

Phase 3 Study 007

www.qrxpharma.com  5

  
  
  
 
 
CEO REVIEW (CONTINUED)       

Q8003IR EFFICACY: PATIENT GLOBAL RATING

s
t
n
e
i
t
a
P

f

o
%

100

90

80

70

60

50

40

30

20

10

0

58.0

43.7

42.9

40.9

13.3

PLACEBO
N = 60

3/2 mg 
N = 48

6/4 mg 
N = 49

12/8 mg 
N = 50

18/12 mg 
N = 49

Phase 3 Study 007

% Good - Excellent Improvement

Under this streamlined clinical development programme, no additional animal pharmacology, toxicology or long-term clinical safety studies 
will be required for regulatory submission. Whilst discussions with the FDA have streamlined the regulatory process, it has also opened 
the door for the Company to reduce fi nancial risk associated with our clinical trial program, with the opportunity to approach the FDA for 
a Special Protocol Assessment (SPA) which will minimise the risk of the FDA requiring further trials or requirements after presentation of 
our planned trial results. During the time of the SPA negotiation, the Company may initiate some additional marketing oriented trials, not 
previously planned, to strengthen both our labelling and marketing assets in preparation for NDA submission and launch as well as strategic 
partnering efforts.

The global market for pain therapies is large and well defined, particularly in the regulated and closely monitored moderate to severe pain 
sector. Q8011CR, a controlled-release dual-opioid® designed to provide 12 hours of pain relief in patients with moderate to severe chronic 
pain, is being formulated to initiate Phase I studies. 

An intravenous (IV) dual-opioid® formulation for immediate, post-surgical treatment of hospital-based pain is proposed and will commence 
clinical trials in 2009. This product candidate broadens the scope of our dual-opioid® portfolio as it will be used in a peri-operative setting.  
Q8012IV represents an exciting addition to the Company’s pain franchise as it is complementary to Q8003IR and Q8011CR, offering 
prescribing physicians broader and better treatment options than traditional opioids.

NEURODEGENERATIVE DISEASES

QRxPharma extends its product portfolio into neurodegenerative disorders with an exclusive worldwide license from the University of 
Alabama on the modulation of key proteins required for normal cellular function in the brain.The discovery relates to a molecule, “Torsin”, 
that works within the cellular machinery to prevent the harmful protein missfolding that characterises neurologic disorders such as dystonia, 
Parkinson’s Disease and Alzheimer’s Disese. A family of small Torsin-activating molecules have been shown in preclinical models to prevent 
protein mutations and to ameliorate movement disorders by working at a causative level. 

6  QRxPharma  Annual Report 2008

  
  
  
 
 
VENOMICS

Based on collaborations with the University of Queensland and the Queensland Institute for Medical Research to identify and characterise 
proteins and peptides from Australian snake venoms, QRxPharma has also developed a unique drug discovery platform for therapies in 
coagulation and blood homeostasis. Venoms from some of the world’s deadliest snakes have proved a fertile area for the discovery of 
novel proteins and peptides with signifi cant therapeutic potential. QRxPharma owns intellectual property assets derived from this research, 
including two preclinical drug candidates in the area of haemostasis, as well as a deep pipeline of earlier stage candidates in haemostasis, 
anti-coagulation and other diverse therapeutic areas. 

SUMMARY

To support these developments, QRxPharma established a presence in New Jersey, US. The Company has recruited a specialised staff 
of outstanding pharmaceutical industry veterans in clinical and commercial development who complement existing management. Key 
appointments of Vice President, Commercialisation; Vice President, Operations; Senior Vice President, Clinical Research; and Senior 
Director, Regulatory Affairs have been completed. This team has been instrumental in completing the initial Phase 3 study of Q8003IR 
ahead of schedule in May 2008.

QRxPharma’s global Scientifi c Advisory Board (SAB) comprises internationally recognised leaders in the fi elds of pain therapy, central 
nervous system drug discovery, pharmaceutical development, regulatory approvals and product commercialisation. Our SAB, chaired by Dr. 
Solomon Snyder, was strengthened during the year with the appointments of Dr. Lester Crawford, former Commissioner of the FDA, and 
Dr. Gavril Pasternak, a world authority on opioid drugs. Counsel from members of the SAB have been of great assistance to QRxPharma 
particularly in dealings with the FDA, as the Company strives to bring to market a product portfolio of late and early stage clinical candidates 
with abbreviated development programmes and improved patient outcomes.

QRxPharma is sharply focused on the advancement of its preclinical and clinical pipeline, emphasising product development in the fi eld 
of pain management.  As clinical trials progress with associated expenditures and reported losses, we will enhance the market value of 
our pain portfolio. QRxPharma retains the funds necessary to meet these commitments throughout the year ahead. We have aligned the 
Company’s development strategy with a concerted effort to broaden our shareholder base and establish strategic partnerships that drive 
value and enable QRxPharma to address larger markets in a global environment. I am very proud of the achievements of the Company 
throughout this past year and I am confi dent that the Company will continue to focus resources and efforts to achieve our goals in 2009.

Yours sincerely,

John W Holaday, PhD
Managing Director and Chief Executive Offi cer

www.qrxpharma.com  7

DIRECTORS’ REPORT

Your directors present their report on the consolidated entity (referred to hereafter as the Group) consisting of QRxPharma Limited (referred 
to hereafter as the Company) and the entities it controlled at the end of, or during, the year ended 30 June 2008.

DIRECTORS

The following persons were directors of QRxPharma Limited during the whole of the fi nancial year and up to the date of this report:

Peter C Farrell 

R Peter Campbell

Gary W Pace

Michael A Quinn

John W Holaday

PRINCIPAL ACTIVITIES

During the year the principal continuing activities of the Group consisted of the development and commercialisation of biopharmaceutical 
products based on largely Australian research, targeting the US market.

DIVIDENDS - QRXPHARMA LIMITED

No dividends were paid or declared since the start of the fi nancial year (2007: $nil).

REVIEW OF OPERATIONS

The Group has made a loss from ordinary activities after income tax for the year of $36.6 million (2007: loss of $0.4 million).This result 
includes non cash charges of $18.1 million relating to an impairment charge to the Torsin intellectual property (Torsin IP) of $14.6 million 
and share-based payments expenses of $3.5 million. The Torsin IP is represented by an exclusive worldwide license from the University of 
Alabama of certain technology relating to the treatment of central nervous system disorders and other related diseases. Excluding these 
charges the loss was in line with expectations in fulfi lling research and development efforts, in the progression of the Company’s clincial 
pipeline candidates and preclinical stage drugs.  The Company continues to closely manage its cash position as it progresses the dual 
opioid Q8003IR Phase 3 development programme, and retains $29.7 million in cash reserves at 30 June 2008.

The impairment charge of $14.6 million (2007: $nil) associated with the Torsin IP was made in accordance with Accounting Standard AASB 
136 “Impairment of Assets” which requires the assessment of the Torsin IP for impairment on an annual basis. The ability of an intangible 
asset such as the Torsin IP to generate suffi cient future economic benefi ts to recover its carrying amount is usually subject to greater 
uncertainty before the asset is capable of generating cash fl ows. Whilst the Company has supported with limited funding the enhancement 
of the Torsin IP, the decision of the Company to focus on pain assets implies the Torsin IP could not currently generate cash fl ow other than 
from the out-license or sale of the asset. As no contracts have been negotiated for the out-license or sale of the Torsin IP, the Company has 
fully impaired the carrying value of the asset at 30 June 2008 being $14.6 million pursuant to the requirements of AASB136.

Apart from its development activities, the Company also initiated a Level 1 American Depositary Receipt programme, listed on the 
International OTCQX, and trading began on 30 June 2008 on the International PrimeQX under the ticker QRXPY.

Further information on the operations and fi nancial position of the Group and its business strategies and prospects is set out on pages 4-7 
of this annual report.

8  QRxPharma  Annual Report 2008

LOSS PER SHARE 

(a)  Basic loss per share 
Loss from continuing operations attributable to the ordinary equity holders of the company

2008
Cents

2007
Cents

(48.8)

(2.8)

(b)  Diluted loss per share 
Loss from continuing operations attributable to the ordinary equity holders of the company

(48.8)

(2.8)

SIGNIFICANT CHANGES IN THE STATE OF AFFAIRS

No signifi cant changes in the state of affairs of the Group were noted during the fi nancial year that have not otherwise been disclosed in this 
report or in the fi nancial statements.

USE OF FUNDS

Expenditure for the year ended 30 June 2008 is refl ective of the Company’s successful IPO in May 2007 and the resultant initiation of its 
Phase 3 clinical trial program for its lead compound, Q8003IR as well as the continued progression of earlier stage pipeline candidates, in 
accordance with the Prospectus dated 27 April 2007.

During the fi nancial year ended 30 June 2007, the Group had entered into a series of foreign exchange put option contracts at an exchange 
rate between Australian dollars and US dollars of AUD1.00 to USD0.8181 to protect against adverse foreign exchange movements 
between AUD and USD. The option contracts were to cover anticipated expenditure of at least $29 million over 2 years to fulfi l research and 
development expenditure associated with clinical trials to be conducted in the United States of America (US). The Prospectus issued by 
the Company on 27 April, 2007 assumed an exchange rate between Australian dollars and US dollars of AUD1.00 to USD0.78. During the 
year the Group converted AUD20 million to USD at an average rate of USD0.9027, taking advantage of the more favourable rates above the 
option contracts.

MATTERS SUBSEQUENT TO THE END OF THE FINANCIAL YEAR

No matter or circumstance has arisen since 30 June 2008 that has signifi cantly affected, or may signifi cantly affect:

(a)  

the Group’s operations in future fi nancial years, or

(b) 

the results of those operations in future fi nancial years, or

(c )  the Group’s state of affairs in future fi nancial years.

LIKELY DEVELOPMENTS AND EXPECTED RESULTS OF OPERATIONS

Information on likely developments in the operations of the Group and the expected results of operations have not been included in this 
annual report because the directors believe it would be likely to result in unreasonable prejudice to the Group.

ENVIRONMENTAL REGULATION

There are no particular and signifi cant environmental regulations under a law of the Commonwealth or of a State or Territory of Australia 
affecting the Group.

www.qrxpharma.com  9

 
DIRECTORS’ REPORT (CONTINUED)

INFORMATION ON DIRECTORS

Peter C Farrell  PhD, ScD, AM.  Non Executive Chairman.

Experience and expertise
Dr Farrell has over 30 years executive and consulting experience in the medical device industry.

Dr Farrell is a Fellow of several professional bodies, including the Australian Institutes of Management and Company Directors. He is the 
Vice Chair of the Executive Council of the Division of Sleep Medicine at Harvard Medical School, he serves on the Board of Trustees of 
University of California, San Diego (UCSD) and is on the Health Sciences Advisory Board of the Dean of Medicine and the Advisory Board 
of UCSD’s Jacobs School of Engineering. Dr Farrell is also a Visiting Professor at the University of New South Wales Graduate School for 
Biomedical Engineering, of which he was founding Director in 1978.

In 1994, the Australian Institution of Engineers awarded Dr Farrell the honour of National Professional Engineer of the Year and, in 1997, 
he received the David Dewhurst Award (Biomedical Engineer of the Year) from the same institution. He was also named San Diego 
Entrepreneur of the Year for Health Sciences in 1998, Australian Entrepreneur of the Year for 2001, and US National Entrepreneur of the 
Year for Health Sciences for 2005. Dr Farrell was admitted to membership of the Order of Australia in 2004. He holds Bachelors and 
Masters degrees in chemical engineering from the University of Sydney and the Massachusetts Institute of Technology (MIT) respectively, a 
PhD in bioengineering from the University of Washington in Seattle, and a ScD from the University of New South Wales for research related 
to dialysis and renal medicine.

Other current directorships
Dr Farrell is the Chairman of ResMed Inc (ASX and NYSE: RMD), which he founded in 1989. He is also a Director of Pharmaxis Limited 
(ASX: PXS) (director since March 2006) and Nuvasive Inc (NASDAQ: NUVA) (director since January 2005) serving on the nominations and 
governance committees.

Former directorships in last 3 years
Nil.

Special responsibilities
Chairman of the Board.

Chairman of nominations committee.

Chairman of remuneration committee.

Interests in shares and options
1,280,540 ordinary shares and 604,089 options over ordinary shares.

John W Holaday  PhD.  Managing Director and Chief Executive Offi cer.

Experience and expertise
Dr Holaday brings four decades of experience as a scientist, founder and executive manager of biotechnology and biopharmaceutical 
companies, and as a banker. Dr Holaday has extensive experience in building publicly traded specialty pharmaceutical companies. In 1992, 
Dr Holaday was a co-founder of EntreMed Inc (NASDAQ: ENMD), of which he served as President, Chief Executive Officer, and Chairman of 
the Board. In 1988, Dr Holaday also co-founded Medicis Pharmaceutical Corporation (NYSE: MRX), where he served as a Board Director, 
as Scientific Director, and as Senior Vice President for Research and Development. Dr Holaday also founded MaxCyte Inc, a cell therapy 
company, where he served as Chairman until retiring in 2003. He founded HarVest Bank of Maryland in 2004, served as Chairman until 
2006 and remains on the Board.  Dr Holaday was founder, Chairman and Chief Executive Offi cer of CNSCo, Inc, a private company which 
was acquired by the Group on 26 April 2007.

Dr Holaday currently serves as an offi cer and Fellow in several biomedical societies, has authored and edited over 200 scientifi c articles in 
journals and books, and holds over 30 patents. He served as Chairman of the Maryland BioAlliance, is a Judge for the Ernst and Young 
Entrepreneur of the Year Award (2003 to present) and was named to the Ernst and Young Entrepreneur of the Year Hall of Fame in 2006. Dr. 
Holaday served as a Captain, US Army, until 1972, and as managing founder of the Neuropharmacology Branch at the Walter Reed Army 
Institute of Research until 1988.  Dr Holaday was formerly an Associate Professor of Anaesthesiology and Critical Care Medicine and Senior 

10  QRxPharma  Annual Report 2008

Lecturer in Medicine at The Johns Hopkins University of Medicine and remains as Adjunct Professor of Psychiatry at the Uniformed Services 
University School of Medicine, Bethesda, Maryland. Dr Holaday obtained his Doctorate in Pharmacology at the University of California, San 
Francisco in 1977. 

Other current directorships
Nil

Former directorships in last 3 years
Nil

Special responsibilities
Managing Director and Chief Executive Offi cer.

President of QRxPharma, Inc.

Member of remuneration committee.

Interests in shares and options
7,543,000 ordinary shares (including ordinary shares held by John Holaday and John Holaday as trustee for the John Holaday Foundation) 
and 805,452 options over ordinary shares.

R Peter Campbell  FCA, FTIA.  Non Executive Director.

Experience and expertise
Mr Campbell is a Chartered Accountant and company Director with more than 35 years of business consulting and advisory experience, 
and operates his own chartered accountancy practice based in Sydney. He is a fellow of both the Institute of Chartered Accountants in 
Australia and the Taxation Institute of Australia and is a registered company auditor. 

Other current directorships
Director and Chair of the audit committees of Silex Systems Limited (ASX: SLX) (director since July 1996), Sonic Healthcare Limited (ASX: 
SHL) (director since January 1993), and Admerex Limited (ASX: ADL) (director since January 2007).

Former directorships in last 3 years
Non executive director of SciGen Limited (ASX: SIE) from August 1999 to February 2005. 

Special responsibilities
Chairman of audit and risk committee.

Member of nominations committee.

Interests in shares and options
85,000 ordinary shares and 241,635 options over ordinary shares.

www.qrxpharma.com  11

DIRECTORS’ REPORT (CONTINUED)

Gary W Pace  PhD  Non-Executive Director and Consultant.

Experience and expertise
Dr Pace is a co founder of QRxPharma Limited and continues to work with the Group.

Dr Pace is a seasoned biopharmaceutical executive with over 30 years of experience in the industry. He has co founded a number of early 
stage life science companies where he built products from the laboratory to commercialisation.

Dr Pace is an elected Fellow of the Australian Academy of Technological Sciences and Engineering, author and co author of over 50 
research papers, reviews and patents. In 2003, Dr Pace was awarded a Centenary Medal by the Australian Government for service to 
Australian society in research and development. Dr Pace holds a Bachelor of Science (Honours) from the University of New South Wales 
and a PhD from Massachusetts Institute of Technology, where he was a Fulbright Scholar.

Other current directorships
Director of ResMed Inc (ASX and NYSE: RMD) (since 1995), Transition Therapeutics Inc (TSX and NASDAQ: TTH;) (since 2002), Celsion 
Corp (AMX: CLN) (since 2002) and Peplin Limited (ASX: PEP) (since June 2004).

Former directorships in last 3 years
Resonance Health Limited (ASX: RHT) (April 2006 to August 2007)

Special responsibilities
Nil

Interests in shares and options
3,230,083 ordinary shares and 402,726 options over ordinary shares.

Michael A Quinn  MBA.  Non-Executive Director.

Experience and expertise
Mr Quinn is managing partner of Innovation Capital and has more than 30 years executive experience in technology companies in Australia, 
the US and the UK. Mr Quinn holds a Bachelor of Science, a Bachelor of Economics, and an MBA from Harvard. Mr Quinn is Chairman 
of the New South Wales Entrepreneurship Centre Limited, a not-for-profi t organisation that trains entrepreneurs.  In 1983 he co-founded 
Memtec Limited (NYSE and ASX), and has also served as Chief Executive Offi cer of an ASX listed  manufacturer and distributor of health 
care and scientifi c products. Mr Quinn has been a Director of several listed companies in Australia, the US and the UK and numerous 
unlisted life science and other technology based companies. 

Other current directorships
Director of ResMed Inc (ASX and NYSE: RMD) (director since 1992) where he chairs the audit committee and Chairman of CAP XX Limited 
(AIM: CPX) (director since November 1998).

Mr Quinn is co-founder and Chairman of Innovation Capital, an Australian and US venture fund, which is a foundation shareholder of the 
Company.

Former directorships in last 3 years
Nil.

Special responsibilities
Member of nominations committee.

Member of audit and risk committee.

Member of remuneration committee.

Interests in shares and options
9,471,749  ordinary shares (including ordinary shares held by Innovation Capital Limited, Innovation Capital LLC, Innovation Capital QRx 
Trust, Innovation Capital QRx II Trust and Kaylara Pty Limited). 402,726 options over ordinary shares (including options held by Innovation 
Capital Limited and Innovation Capital LLC).

12  QRxPharma  Annual Report 2008

 
COMPANY SECRETARY

Chris J Campbell holds a Bachelor of Commerce and is an Associate of the Institute of Chartered Accountants in Australia. He also holds 
the position of Chief Financial Offi cer of QRxPharma Limited. He has over 25 years experience with major accounting fi rms and as CFO of 
publicly traded companies.

Terrence F Sayer also held the offi ce of Company Secretary from the beginning of the fi nancial year until his resignation on 6 February 2008.

MEETINGS OF DIRECTORS

The numbers of meetings of the company’s board of directors and of each board committee held during the year ended 30 June 2008, and 
the numbers of meetings attended by each director were:

Full meetings of 
directors

Meetings of 
non-executive 
directors

Meetings of committees

Audit and risk

Nominations

Remuneration

A

5

5

4

5

5

B

5

5

5

5

5

A

5

4

3

5

B

5

5

3

5

A

**

**

3

**

3

B

3

3

A

1

**

1

**

1

B

1

1

1

A

2

2

**

**

2

B 

2

2

2

Peter C Farrell

John W Holaday* 

R Peter Campbell 

Gary W Pace

Michael A Quinn

A = Number of meetings attended
B = Number of meetings held during the time the director held offi ce or was a member of the committee during the year
* = Not a non executive director
** = Not a member of the relevant committee

REMUNERATION REPORT

The remuneration report is set out under the following main headings:

A  Principles used to determine the nature and amount of remuneration

B  Details of remuneration

C Service agreements

D Share-based compensation

E  Additional information.

The information provided under headings A-D includes remuneration disclosures that are required under Accounting Standard AASB 124 
Related Party Disclosures.  These disclosures have been transferred from the fi nancial report and have been audited.  The disclosures in 
Section E are additional disclosures required by the Corporations Act 2001 and the Corporations Regulations 2001 which have not been 
audited.

www.qrxpharma.com  13

 
DIRECTORS’ REPORT (CONTINUED)

A   Principles used to determine the nature and amount of remuneration (audited)

As a company building a speciality pharmaceutical business to compete internationally, QRxPharma Limited requires a board and senior 
management team that have both the technical capability and relevant business experience to execute the Group’s strategy.

The objective of the Group’s executive reward framework is to ensure reward for performance is competitive and appropriate for the results 
delivered.  The framework aligns executive reward with achievement of strategic objectives and the creation of value for shareholders, and 
conforms with market practice for delivery of reward.  The Board ensures that executive reward satisfi es the following key criteria for good 
reward governance practices:

(cid:129)    competitiveness and reasonableness

(cid:129)    acceptability to shareholders

(cid:129)   

transparency

The Group has structured an executive remuneration framework that is market competitive and complementary to the reward strategy of 
the organisation.

Alignment to shareholders’ interests:

(cid:129)   

focuses on sustained growth in share price as well as focusing the executive on key non fi nancial drivers of value

(cid:129)    attracts and retains high calibre executives.

Alignment to program participants’ interests:

(cid:129)   

(cid:129)   

rewards capability and experience

refl ects competitive reward for contribution to growth in shareholder wealth

(cid:129)    provides recognition for contribution.

The framework provides a blend of fi xed pay, and short and long term incentives. 

The board has established a remuneration committee which provides advice on remuneration and incentive policies and practices and 
specifi c recommendations on remuneration packages and other terms of employment for executive directors, other senior executives and 
non executive directors.  The Corporate Governance Statement provides further information on the role of this committee. 

Non-executive directors

Fees and payments to non executive directors refl ect the demands which are made on, and the responsibilities of, the directors.  The fees 
were set on 27 April 2007 ahead of the Company completing its initial public offering. There is an annual base fee payable six months in 
arrears, currently $60,000 for the Chairman and $40,000 for the other non executive directors (which also covers serving on a committee) 
and long term incentives through participation in the QRxPharma Limited Employee Share Option Plan.  

Non executive directors’ fees are determined within an aggregate directors’ fee pool limit, which is periodically recommended for approval 
by shareholders.  The maximum currently stands at $400,000 per annum and was approved by shareholders at the Annual General Meeting 
on 24 April 2007.

Executive pay

The executive pay and reward framework has three components:

(cid:129)    base pay and benefi ts, including superannuation

(cid:129)    short term performance incentives, and

(cid:129)   

long term incentives through participation in the QRxPharma Limited Employee Share Option Plan.

The combination of these comprises the executive’s total remuneration.

14  QRxPharma  Annual Report 2008

Base pay

Structured as a total employment package which may be delivered as a combination of cash and prescribed non fi nancial benefi ts at the 
executives’ discretion.

Executives are offered a competitive base pay that comprises the fi xed component of pay and rewards.  Base pay for executives is 
reviewed annually and every two years a market survey is conducted to ensure the executive’s pay is competitive with the market.  An 
executive’s pay is also reviewed on promotion.

There are no guaranteed base pay increases included in any executives’ contracts.

Benefi ts

Executives receive benefi ts including health insurance and tax advisory services.

Superannuation

The Group does not maintain a Group superannuation plan. The Group makes fi xed percentage contributions for  Australian resident 
employees to complying third party superannuation funds and for US resident employees to complying pension plans.

Short term incentives

A variable cash incentive component is payable annually dependant upon achievement of performance targets. Individual performance 
targets are set by reference to components of the Group’s business plan for which the individual executive is responsible.

Long term incentives

Long term incentives are provided to certain employees through participation in the QRxPharma Limited Employee Share Option Plan.

B   Details of remuneration (audited)

Amounts of remuneration

Details of the remuneration of the directors and the key management personnel (as defi ned in AASB 124 Related Party Disclosures) of 
QRxPharma Limited and the Group are set out in the following tables.

The key management personnel of QRxPharma Limited and the Group includes the directors as per pages 10 to 12 and the following 
executive offi cers who have authority and responsibility for planning, directing and controlling the activities of the Group, who are also the 
highest paid executives of the entity:

(cid:129)    Warren C Stern, PhD – Executive Vice President, Drug Development 

(cid:129)    Chris J Campbell – Chief Financial Offi cer and Company Secretary 

(cid:129)    Douglas A Saltel – Chief Operating Offi cer (resigned 7 March 2008)

(cid:129)    Joseph J Berry – VP Operations (from 12 November 2007)

(cid:129)    Philip J Magistro – VP Commercial Operations (from 26 November 2007)

(cid:129)    Patricia T Richards, MD – Senior VP Clinical Research (from 18 February 2008)

www.qrxpharma.com  15

 
DIRECTORS’ REPORT (CONTINUED)

Key management personnel and other executives of QRxPharma Limited and the Group are the same

Short-term employee benefi ts

Post-employment 
benefi ts

Long-term benefi ts

Cash 

salary and 

fees

$

Cash 

bonus

$

Non-

monetary 

Super-

Retirement 

benefi ts

Other

annuation

benefi ts

Options

$

$

$

$

Long 

$

Total

$

2008

Name

Non executive directors

Peter C Farrell

R Peter Campbell

Michael A Quinn

Gary W Pace

60,000

40,000

40,000

59,765

-

-

-

-

-

Sub-total non-executive 
directors

199,765

Executive directors

John W Holaday 

350,000

146,250

Other key management personnel (Group)

Douglas A Saltel 

(resigned 7 March 2008) 

Warren C Stern ^ 

Chris J Campbell ^ 

Joseph J Berry ^ 

208,788

56,744

227,665

197,248

150,550

90,879

75,000

70,458

(appointed 12 November 2007)

Philip J Magistro ^ 

147,684

73,528

(appointed 26 November 2007)

Patricia T Richards ^ 

99,533

29,860

(appointed 18 February 2008)

Total key management 
personnel compensation 
(Group)

Other Group executives

Terrence F Sayer 

(Company Secretary) 

1,581,233 542,719

(resigned 6 February 2008)

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

3,600

-

-

3,600

-

-

-

24,502

-

-

-

28,102

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

  296,083

118,433

197,388

278,241

356,083

162,033

237,388

338,006

890,145

1,093,510

-

556,482

1,052,732

-

265,532

556,482

228,017

32,598

875,026

524,767           

253,606

43,463

264,675

54,026

183,419

-

2,361,213

4,513,267

-

-

-

^ denotes one of the highest paid executives of the company, as required to be disclosed under the Corporations Act 2001. 

Gary Pace was paid $239,443 for consulting services provided to the Company during the year, after ceasing as an employee on 
30 September 2007.

Terrence F Sayer was paid $53,120 for Accounting and Offi ce Services and Company Secretarial duties provided to the Company during the year. 

16  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
Key management personnel and other executives of QRxPharma Limited and the Group were the same in 2007

Short-term employee benefi ts

Cash 

Non-

Post-employment 
benefi ts

Share-
based 
payments

Long-
term 
benefi ts

Long 

salary and 

Cash 

monetary 

Super-

Retirement 

service 

bonus

benefi ts

Other

annuation

benefi ts

leave

Options

$

$

$

$

$

$

$

Total

$

2007

Name

Non executive directors

Peter C Farrell

R Peter Campbell

Michael A Quinn

David Stack 

(resigned 27 April 2007)

Michael S Hirshorn 

(resigned 27 April 2007) 

George Savage 

(resigned 27 April 2007) 

David A Henderson 

(resigned 27 April 2007)

Sub-total non-executive 
directors

Executive directors

John W Holaday 

Gary W Pace

Douglas A Saltel ^ 

Warren C Stern ^ 

Felix de la Iglesia 

(resigned 25 May 2007)

Chris J Campbell ^ 

B Nicholas Harvey ^ 

(resigned 1 March 2007)

Total key management 
personnel compensation 
(Group)

Other Group executives

Terrence F Sayer 

(Company Secretary) 

fees

$

10,000

6,667

6,667

-

-

-

-

23,334

79,295

97,209

72,086

51,173

-

63,651

-

-

-

-

-

-

-

-

-

-

58,977

-

-

-

-

-

386,748

58,977

-

-

Other key management personnel (Group)

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-
-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-
-

-

-

-

8,327

-

8,327

-

-

-

-

-

-

-

-

-

-
-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-
-

-

-

-

-

-

-

-

  8,723

3,489

5,815

23,215

18,723

10,156

12,482

23,215

-

-

-

-

-

-

41,242

64,576

29,076

25,291

108,371

181,477

29,076

29,076

-

101,162

80,249

-

17,446

89,424

-

-

171,207

625,259

-

-

^ denotes one of the highest paid executives of the Group, as required to be disclosed under the Corporations Act 2001.

Felix de la Iglesia was paid $264,830 for consulting services provided to the Group during the year.

B Nicholas Harvey was paid $52,386 for consulting services provided to the Group during the year.

Terrence F Sayer was paid $83,373 for Accounting and Offi ce Services and Company Secretarial duties provided to the Company during the year. 

David Stack was paid $4,500 for consulting services provided to the Group during the year.

www.qrxpharma.com  17

 
 
 
 
 
 
 
 
 
 
DIRECTORS’ REPORT (CONTINUED)

Key management personnel and other executives of the Group

The relative proportions of remuneration that are linked to performance and those that are fi xed are as follows:

Name

2008

2007

2008

2007

2008

2007

Fixed remuneration

At risk - STI

At risk - LTI

Directors of QRxPharma Limited

John W Holaday
Peter C Farrell
R Peter Campbell
Michael A Quinn
Gary W Pace 
David Stack 
(resigned 27 April 2007)

86%
100%
100%
100%
100%
-

Other key management personnel of the Group

Douglas A Saltel 
(resigned 7 March 2008)
Warren C Stern
Chris J Campbell
Joseph J Berry 
(appointed 12 November 2007)
Philip J Magistro 
(appointed 26 November 2007)
Patricia T Richards 
(appointed 18 February 2008)
Felix de la Iglesia 
(resigned 25 May 2007)
B Nicholas Harvey 
(resigned 1 March 2007)

79%

90%
86%
72%

72%

84%

-

-

C   Service agreements (audited)

100%
100%
100%
100%
62%
100%

100%

100%
100%
-

-

-

100%

100%

14%
-
-
-
-
-

21%

10%
14%
28%

28%

16%

-

-

-
-
-
-
38%
-

-

-
-
-

-

-

-

-

-
-
-
-
-
-

-

-
-
-

-

-

-

-

-
-
-
-
-
-

-

-
-
-

-

-

-

-

On appointment to the board, all non executive directors enter into a service agreement with the company in the form of a letter of 
appointment.  The letter summarises the board policies and terms, including compensation, relevant to the offi ce of director.  

Remuneration and other terms of employment for the Managing Director and Chief Executive Offi cer and the other Key Management 
personnel are also formalised in service agreements.  Each of these agreements provide for the provision of performance related cash 
bonuses, other benefi ts including health insurance and tax advisory services, and participation, when eligible, in the QRxPharma Limited 
Employee Share Option Plan.  Other major provisions of the agreements relating to remuneration are set out below.

John W Holaday, Managing Director and Chief Executive Offi cer

(cid:129)    Term of agreement – 2 years (with annual extension) commencing 14 April 2007.

(cid:129)    Base salary, inclusive of retirement or pension contribution, for the year ended 30 June 2008 of $350,000, to be reviewed  

  annually by the remuneration committee.

(cid:129)    Payment of a termination benefi t on early termination by the Company, other than for gross misconduct, equal to the annual  

  base salary and a bonus component of $150,000.

18  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
 
Warren C Stern,  Executive Vice President Drug Development

(cid:129)    Term of agreement – 3 years (with annual extension) commencing 14 April 2007.

(cid:129)    Base salary, inclusive of retirement or pension contribution, for the year ended 30 June 2008 of US$250,000 to be reviewed annually  

  by the remuneration committee.

(cid:129)    Payment of a termination benefi t on early termination by the Company, other than for gross misconduct, equal to the annual base    

  salary and a bonus component of US$100,000.

Joseph J Berry, Vice President Operations

(cid:129)    Term of agreement – ongoing, commencing 12 November 2007.

(cid:129)    Base salary, inclusive of retirement or pension contribution, for the year ended 30 June 2008 of US$215,000 (pro rata from  

  commencement date), to be reviewed annually by the remuneration committee.

Philip J Magistro, Vice President Commercialisation

(cid:129)    Term of agreement – ongoing commencing 26 November 2007.

(cid:129)    Base salary, inclusive of retirement or pension contribution, for the year ended 30 June 2008 of US$225,000 (pro rata from  

  commencement date), to be reviewed annually by the remuneration committee.

Patricia T Richards, Senior Vice President Clinical Research

(cid:129)    Term of agreement – ongoing, commencing 18 February 2008.

(cid:129)    Base salary, inclusive of retirement or pension contribution, for the year ended 30 June 2008 of US$250,000 (pro rata from  

  commencement date), to be reviewed annually by the remuneration committee.

Chris J Campbell, Chief Financial Offi cer

(cid:129)    Term of agreement – ongoing, commencing 1 March 2007.

(cid:129)    Base salary, inclusive of superannuation, for the year ended 30 June 2008 of $215,000, to be reviewed annually by the remuneration  

  committee.

(cid:129)    Payment of a termination benefi t on early termination without notice by the Company, other than for gross misconduct, equal to 3    

  months salary.

Gary W Pace, Non-Executive Director, Consultant

(cid:129)    Term of agreement – 1 year, commencing 25 May 2008.

(cid:129)    Base consulting fee for the year ended 30 June 2009 of US$100,000 (pro rata).

(cid:129)    No termination benefi t payable on early termination by the Company.

D   Share-based compensation (audited)

Options

Options over shares in QRxPharma Limited are granted under the QRxPharma Limited Employee Share Option Plan (ESOP). The ESOP 
is designed to provide long term incentives for executives to deliver long term shareholder returns. 

The maximum number of options available to be issued under the ESOP is 10% of diluted ordinary share capital in the Company as at the 
date of issue of the relevant options. All employees and directors are eligible to participate in the ESOP, but do so at the invitation of the 
Remuneration Committee. The term of option issues are determined by the Remuneration Committee.

www.qrxpharma.com  19

 
 
 
 
 
 
 
 
 
 
 
DIRECTORS’ REPORT (CONTINUED)

Options are generally granted for no consideration and vest annually over 3 years in equal proportions with the initial vesting on the fi rst 
anniversary of the date of grant. The exercise price is set by the Remuneration Committee but being not less than the market price of 
ordinary shares immediately prior to the grant date of the options.

Options granted under the plan carry no dividend or voting rights. When exercisable, each option is convertible into one ordinary share.

The terms and conditions of each grant of options affecting remuneration in the previous, this or future reporting periods are as follows:

Grant date

Vested and exercisable

Expiry date

Exercise price

Value per option at grant 
date

31 March 2007
14 April 2007
25 May 2007
25 May 2007
1 September 2007
1 October 2007
9 October 2007
1 January 2008
1 April 2008
1 April 2008

Over 3 years
Over 3 years
Over 3 years
Over 3 years
Over 3 years
Over 3 years
Over 3 years
Over 3 years
Over 3 years
Over 3 years

31 March 2014
14 April 2014
25 May 2014
25 May 2014
1 September 2014
1 October 2014
9 October 2014
1 January 2015
1 April 2015
1 April 2015

$1.42
$1.00
$1.00
$2.00
$1.70
$1.45
$1.34
$1.11
$1.05
$1.04

$1.31
$1.46
$1.46
$1.15
$0.98
$0.83
$0.77
$0.64
$0.60
$0.60

The exercise price in respect of an option granted shall be the market price for a share prevailing at the time of grant unless the Board 
decides otherwise. Options will lapse if they are not exercised before the expiration date or if the option holder leaves the employment of 
the Group.

Details of options over ordinary shares in the company provided as remuneration to each director of QRxPharma Limited and each of the 
key management personnel of the parent entity and the Group are set out below.  When exercisable, each option is convertible into one 
ordinary share of QRxPharma Limited.  Further information on the options is set out in note 28 to the fi nancial statements.

Name

Directors of QRxPharma Limited

Peter C Farrell
R Peter Campbell
Michael A Quinn
Gary W Pace
John W Holaday
Ronald M Cresswell (resigned 10 February 2006)
David Stack (resigned 27 April 2007)

Other key management personnel

Douglas A Saltel (resigned 7 March 2008)
Warren C Stern
Chris J Campbell
Felix de la Inglesia (resigned 25 May 2007)
Joseph J Berry (appointed 12 November 2007)
Philip J Magistro (appointed 26 November 2007)
Patricia T Richards (appointed 18 February 2008)

Number of options granted
during the year

Number of options vested
during the year

2008

2007

2008

2007

-
-
-
-
-
-
-

-
-
-
-
150,000
200,000
500,000

604,089
241,635
402,726
402,726
805,452
-
-

805,452
805.452
402,726
50,000
-
-
-

201,363
80,545
134,242
134,242
268,484
-
-

-
268,484
134,242
-
-
-
-

-
-
-
-
-
50,000
180,000

-
-
-
-
-
-
-

The assessed fair value at grant date of options granted to the individuals is allocated equally over the period from grant date to vesting 
date, and the amount is included in the remuneration tables above.  Fair values at grant date are independently determined using a Black 
Scholes option pricing model that takes into account the exercise price, the term of the option, the impact of dilution, the share price at 
grant date and expected price volatility of the underlying share, the expected dividend yield and the risk free interest rate for the term of 
the option.

20  QRxPharma  Annual Report 2008

The model inputs for options granted during the year ended 30 June 2008 included:

(a)  Options are granted for no consideration and vest over 3 years (see page 20)

(b)  Exercise price: $1.05 to $1.11 (2007: $0.15 to $2.00)

(c)  Grant date: 1 January 2008 to 1 April 2008 (2007: 31 March 2007 to 25 May 2007)

(d)  Expiry date: 1 January 2015 and 1 April 2015 (2007: 2014)

(e)  Expected price volatility of the company’s shares: 60% (2007: 60%)

(f)   Expected dividend yield: nil% (2007: nil%)

(g)  Risk free interest rate: 6.25% (2007: 6.25%).

Shares provided on exercise of remuneration options

Details of ordinary shares in the company provided as a result of the exercise of remuneration options to each director of QRxPharma 
Limited and other key management personnel of the Group are set out below.

Name

Directors of QRxPharma Limited

Gary W Pace
Gary W Pace
David Stack (resigned 27 April 2007)
David Stack (resigned 27 April 2007)
Ronald M Cresswell (resigned 10 February 2006)

Other key management personnel of the Group

Felix de la Iglesia (resigned 25 May 2007)
B Nicholas Harvey (resigned 1 March 2007)

Date of exercise 
of options

Number of ordinary shares issued on 
exercise of options during the year *

2008

2007

1 March 2007
25 April 2007**
1 March 2007
25 April 2007**
25 April 2007

25 April 2007**
25 May 2007

-
-
-
-
-

-
-

207,096
71,689
447,096
154,768
42,500

88,996
131,788

* Number of ordinary shares issued prior to compression of shares.

**The options exercised above carried anti dilution provisions which resulted in an uplift of shares issued on 25 April 2007. No amount 
was payable on these shares.

The amounts paid per ordinary share by each director and other key management personnel on the exercise of options at the date of 
exercise were as follows:

Exercise date   

Amount paid per share

18 June 2006   
1 March 2007  
25 May 2007   

$0.15
$0.15
$0.15

No amounts are unpaid on any shares issued on the exercise of options.

www.qrxpharma.com  21

 
 
 
 
 
 
 
DIRECTORS’ REPORT (CONTINUED)

E   Additional information unaudited

Share-based compensation: Options

A

B

C

D

E

Remuneration 
consisting of 
options

Value at grant date
$

Value at exercise date
$

Value at lapse date
$

61.5%
49.0%
61.5%
18.2%
58.0%
-
25.8%
14.4%
4.8%
6.2%
12.5%

541,514
216,605
361,009
1,049,039 
524,520
1,049,039
1,049,039
444,784
114,293
152,390
380,976

-
-
-
-
-
-
-
-
-
-
-

 -
-
-
-
-
1,049,039 
-
-
-
-
-

Total of 
columns B D
$

541,514
216,605
361,009
1,049,039
524,520
-
1,049,039
444,784
114,293
152,390
380,976

Name

Peter C Farrell
R Peter Campbell
Michael A Quinn
John W Holaday 
Gary W Pace
Douglas A Saltel
Warren C Stern
Chris J Campbell
Joseph Berry
Philip Magistro
Patricia Richards

A =  The percentage of the value of remuneration consisting of options, based on the value of options expenses during the  

 current year.

B =  The value at grant date calculated in accordance with AASB 2 Share-based Payment of options granted during the year

 as part of remuneration.

C =  The value at exercise date of options that were granted as part of remuneration and were exercised during the year, 

  being the intrinsic value of the options at that date.

D =  The value at lapse date of options that were granted as part of remuneration and that lapsed during the year.

Shares under option
Unissued ordinary shares of QRxPharma Limited under option at the date of this report are as follows:

Date options granted

Expiry date

Issue price of shares

Number under option

31 March 2007
14 April 2007
25 May 2007
25 May 2007
25 May 2007
1 September 2007
1 October 2007
9 October 2007
1 January 2008
1 April 2008
1 April 2008

31 March 2014
14 April 2014
25 May 2014
25 May 2014
25 May 2010
1 September 2014
1 October 2014
9 October 2014
1 January 2015
1 April 2015
1 April 2015

$1.42
$1.00
$1.00
$2.00
$2.20
$1.70
$1.45
$1.34
$1.11
$1.05
$1.04

402,726
2,013,630
552,726
1,448,450
322,181
50,000
75,000
50,000
350,000
600,000
75,000

 5,939,713

Shares issued on the exercise of options

No ordinary shares have been issued during the year ended 30 June 2008 on the exercise of options granted under the QRxPharma 
Limited Employee Option Plan

22  QRxPharma  Annual Report 2008

     
     
     
INDEMNIFICATION

The Company has entered into Deeds of Access, Indemnity and Insurance with each of the directors and executive offi cers of the Group 
against all liabilities to another person (other then the Company or a related body corporate) that may arise from their position as directors 
and executive offi cers of the Company and its controlled entities, except where the liability arises out of conduct involving a lack of good 
faith. The agreement stipulates that the Company will meet the amount of any such liabilities, including costs and expenses.

INSURANCE OF OFFICERS

The directors have not included details of the nature of liabilities covered nor the amount of the premium paid in respect to Directors and 
Offi cers liability insurance contracts, as such disclosure is prohibited under the terms of the contracts.

PROCEEDINGS ON BEHALF OF THE COMPANY

No person has applied to the Court under section 237 of the Corporations Act 2001 for leave to bring proceedings on behalf of the 
company, or to intervene in any proceedings to which the company is a party, for the purpose of taking responsibility on behalf of the 
company for all or part of those proceedings.

No proceedings have been brought or intervened in on behalf of the company with leave of the Court under section 237 of the 
Corporations Act 2001.

NON-AUDIT SERVICES

The company may decide to employ the auditor on assignments additional to their statutory audit duties where the auditor’s expertise 
and experience with the company and/or the Group are important.

Details of the amounts paid or payable to the auditor (PricewaterhouseCoopers) for audit and non audit services provided during the year 
are set out below.

The board of directors has considered the position and, in accordance with advice received from the audit committee, is satisfi ed that the 
provision of the non audit services is compatible with the general standard of independence for auditors imposed by the Corporations Act 
2001.  The directors are satisfi ed that the provision of non audit services by the auditor, as set out below, did not compromise the auditor 
independence requirements of the Corporations Act 2001 for the following reasons:

(cid:129)    all non audit services have been reviewed by the audit committee to ensure they do not impact the impartiality and objectivity of the  

  auditor

(cid:129)    none of the services undermine the general principles relating to auditor independence as set out in APES 110 Code of Ethics for    

  Professional Accountants.

1. Audit services

PricewaterhouseCoopers Australian fi rm:

Audit and review of fi nancial reports and other audit work 
under the Corporations Act 2001

Total remuneration for audit services

2. Non audit services

PricewaterhouseCoopers Australian fi rm:

Audit related services

Taxation services

Total remuneration for non audit services

Consolidated

2008

2007

86,000

86,000

-

99,270

99,270

97,200

97,200

145,000

80,300

225,300

www.qrxpharma.com  23

 
 
 
DIRECTORS’ REPORT (CONTINUED)

AUDITOR’S INDEPENDENCE DECLARATION

A copy of the auditor’s independence declaration as required under section 307C of the Corporations Act 2001 is set out on page 25.

ROUNDING OF AMOUNTS

The company is a kind referred to in Class order 98/100, issued by the Australian Securities and Investments Commission, relating to the 
“rounding off” of amounts in the fi nancial report.  Amounts in the directors’ report have been rounded off in accordance with that Class 
Order to the nearest thousand dollars, or in certain cases, the nearest dollar.

AUDITOR

PricewaterhouseCoopers continues in offi ce in accordance with section 327 of the Corporations Act 2001.

This report is made in accordance with a resolution of directors.

Peter C Farrell  
Director   

Sydney
25 August 2008

24  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
AUDITORS’ INDEPENDENCE DECLARATION

PricewaterhouseCoopers
ABN 52 780 433 757
Darling Park Tower 2
201 Sussex Street
GPO BOX 2650
SYDNEY NSW 1171
DX 77 Sydney
Australia
www.pwc.com/au
Telephone +61 2 8266 0000
Facsimile +61 2 8266 9999

AUDITOR’S INDEPENDENCE DECLARATION 

As lead auditor for the audit of QRxPharma Limited for the year ended 30 June 2008 I declare that to the best of my knowledge and 
belief, there have been:

(a) 

(b) 

no contraventions of the auditor independence requirements of the Corporations Act 2001 in relation to the audit; and

no contraventions of any applicable code of professional conduct in relation to the audit.

This declaration is in respect of QRxPharma Limited and the entities it controlled during the period.

Manoj Santiago 
Partner 
PricewaterhouseCoopers 

Sydney
25 August 2008

Liability limited by a scheme approved under Professional Standards Legislation

www.qrxpharma.com  25

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CORPORATE GOVERNANCE STATEMENT

QRxPharma Limited (the Company) and the board are committed 
to achieving and demonstrating the highest standards of corporate 
governance. The board continues to review the framework and 
practices to ensure they meet the interests of shareholders and 
other key stakeholders in the Company. The Company and its 
controlled entities together are referred to as the Group in this 
statement.

The relationship between the board and senior management 
is critical to the Group’s long term success. The directors are 
responsible to the shareholders for the performance of the 
Group in both the short and the longer term and seek to balance 
sometimes competing objectives in the best interests of the Group 
as a whole. Their focus is to enhance the interests of shareholders 
and other key stakeholders and to ensure the Group is properly 
managed.

The role of the board is to provide strategic guidance and effective 
oversight of management. The directors are responsible for the 
overall direction, long term objectives and strategy, performance, 
compliance and policies. Day to day management of the Group’s 
affairs inclusive of the implementation of the corporate objectives 
and strategy and compliance and policy initiatives are delegated by 
the board to the Managing Director and other senior management, 
with regular consultation between the Managing Director and the 
Chairman occurring on matters generally as they arise. 

A description of the company’s main corporate governance 
practices is set out below.

The Board of Directors

The board operates in accordance with the broad principles 
set out in its charter which is available from the corporate 
governance information section of the company website at www.
qrxpharma.com. The charter details the board’s composition and 
responsibilities.

Board composition

The charter states:

(cid:129)  the board is committed to ensuring that there will be a least  
  fi ve directors of whom a majority will be non executive directors.  
  Non executive directors bring a fresh perspective to the board’s  
  consideration of strategic, risk and performance matters and are  
  best placed to exercise independent judgement and review and  
  constructively challenge the performance of management

(cid:129)  where possible the non executive directors be independent.  
  This is in recognition of the importance of independent views  
  and the board’s role in supervising the activities of management  
  and independent judgement in board decision making

(cid:129)  the board is also committed to ensuring that its members have a  
  broad range of skills, experience and expertise. This will assist  

26  QRxPharma  Annual Report 2008

the board to maximise performance and ensure appropriate  
levels of shareholder return

(cid:129)  the board is required to undertake an annual review of its  
  performance and Charter to ensure that it is operating effectively  
  and in the best interests of the Group

Responsibilities

The board is ultimately responsible for the business and 
management of the Group and specifi c responsibilities of the 
board include:

(cid:129)  overseeing the business and strategic direction of the Group in  
  order to maximise performance and generate appropriate levels  
  of shareholder return

(cid:129)  ensuring that management establishes and follows an    
  appropriate system of internal controls, risk management and  

legal compliance

(cid:129)  reviewing the performance and implementation of  
  corporate strategies by senior management and ensuring  
  senior management have the necessary resources to do so

(cid:129)  approving and supervising signifi cant capital expenditure,  
  capital management, acquisitions and divestments

(cid:129)  appointment, performance assessment and, if necessary,  

removal of the Chairman, Chief Executive Offi cer, Chief Financial  

  Offi cer and the Company Secretary

(cid:129)  approving and monitoring annual budgets and strategic plans

(cid:129)  approving and monitoring fi nancial and other reporting made  
to shareholders and the ASX under the continuous disclosure  
regime.

Board members

Details of the members of the board, their experience, expertise, 
qualifi cations, term of offi ce and independent status are set out in 
the directors’ report under the heading ‘’Information on directors’’. 
There are four non executive directors, two of whom are deemed 
independent under the principles set out below, and one executive 
director at the date of signing the directors’ report.

The board seeks to ensure that:

(cid:129)  at any point in time, its membership represents an appropriate  
  balance between directors with experience and knowledge of  
the Group and directors with an external or fresh perspective

(cid:129)  the size of the board is conducive to effective discussion and  
  effi cient decision making.

 
 
 
 
 
 
 
 
Directors’ independence

Term of offi ce

The board has adopted specifi c principles in relation to directors’ 
independence. These state that to be deemed independent, a 
director must be a non executive and:

The Company’s Constitution specifi es that all directors excluding 
the managing director must retire from offi ce no later than the third 
annual general meeting (AGM) following their last election. 

(cid:129)  not be a substantial shareholder of the Company or an offi cer of,  
  or otherwise associated directly with, a substantial shareholder  
  of the Company

(cid:129)  within the last three years, not have been employed in    
  an executive capacity by the Company or any other Group  
  member,  or been a director after ceasing to hold any such  
  employment

(cid:129)  within the last three years not have been a principal of a material  
  professional adviser or a material consultant to the Company or  
  any other Group member, or an employee materially associated  
  with the service provided

(cid:129)  not be a material supplier or customer of the Company or any  
  other Group member, or an offi cer of or otherwise associated  
  directly or indirectly with a material supplier or customer

(cid:129)  must have no material contractual relationship with the company  
  or a controlled entity other than as a director of the Group

(cid:129)  not have been on the board for a period which could, or  
  could reasonably be perceived to, materially interfere with  
the director’s ability to act in the best interests of the Group

(cid:129)  be free from any interest and any business or other relationship  
  which could, or could reasonably be perceived to, materially  

interfere with the director’s ability to act in the best interests of  
the Group.

At present, materiality for these purposes is determined as a 
relationship or contract where the Company or Group pays in 
excess of $100,000. 

Recent thinking on corporate governance has introduced the view 
that a director’s independence may be perceived to be impacted 
by lengthy service on the board. To avoid any potential concerns, 
the board has determined that a director will not be deemed 
independent if he or she has served on the board of the company 
for more than ten years. 

Non executive directors

The four non executive directors met fi ve times during the year, 
in scheduled sessions without the presence of management, to 
discuss the operation of the board and a range of other matters. 
Relevant matters arising from these meetings were shared with the 
full board.

Chairman

The Chairman is responsible for leading the board, ensuring 
directors are properly briefed in all matters relevant to their role and 
responsibilities, facilitating board discussions and managing the 
board’s relationship with the Group’s senior executives.

Chief Executive Offi cer (CEO)

The CEO is responsible for implementing Group strategies and 
policies. 

Commitment

The number of meetings of the Company’s board of directors and 
of each board committee held during the year ended 30 June 2008, 
and the number of meetings attended by each director is disclosed 
on page 13.

The board will meet as frequently as required but must not meet less 
than four times each year.

The commitments of non executive directors are considered by the 
nomination committee prior to the directors’ appointment to the 
board of the Company. 

Independent professional advice

Directors and board committees have the right, in connection with 
their duties and responsibilities, to seek independent professional 
advice. With the approval of the Chairman this advice will be at the 
expense of the Company.

Avoidance of confl ict of interest

In addition to the issue of independence, the directors have a 
continuing responsibility to avoid confl icts of interest (both real 
and apparent) between their duty to the Company and their own 
interests. Directors are required to disclose any actual or potential 
confl ict of interest on appointment and are required to keep this 
disclosure up to date. A director that has an actual or potential 
confl ict must immediately inform the board and remove themselves 
from any discussions or decision making in relation to the actual or 
potential confl ict. 

Performance assessment

The board undertakes an annual self assessment of its collective 
performance, the performance of the Chairman and its committees.  
The results and any action plans are documented together with 
specifi c performance goals which are agreed for the coming year.

www.qrxpharma.com  27

 
 
 
CORPORATE GOVERNANCE STATEMENT (CONTINUED)

Corporate reporting

The main responsibilities of the committee include:

The Managing Director and CFO have made the following 
certifi cations to the board:

(cid:129)  reviewing management succession planning for the Company  

in general but specifi cally in regards to the CEO and other senior  

(cid:129)  that the Company’s fi nancial reports are complete and present  
  a true and fair view, in all material respects, of the fi nancial  
  condition and operational results of the Company and Group  
  and are in accordance with relevant accounting standards

  management

(cid:129)  reviewing the appointments and terminations to senior executive  
  positions reporting to the CEO

(cid:129)  reviewing and making recommendations to the board regarding  

(cid:129)  that the above statement is founded on a sound system of  

the appointment of non executive directors, including:

risk management and internal compliance and control which  
implements the policies adopted by the board and that the  
  Company’s risk management and internal compliance and  
  control is operating effi ciently and effectively in all material  

respects.

Board committees

The board has established a number of committees to assist in 
the execution of its duties and to allow detailed consideration 
of complex issues. Current committees of the board are the 
nominations, remuneration and audit and risk committees. The 
nominations and audit and risk committees are comprised entirely of 
non executive directors.

Each committee has its own written charter setting out its role and 
responsibilities, composition, structure, membership requirements 
and the manner in which the committee is to operate. All of these 
charters are reviewed on an annual basis and are available on 
the Company website. All matters determined by committees are 
submitted to the full board as recommendations for board decisions.

Minutes of committee meetings are tabled at the subsequent 
board meeting. Additional requirements for specifi c reporting by 
the committees to the board are addressed in the charter of the 
individual committees.

Nominations committee

The nominations committee is currently comprised of Peter C 
Farrell (Chairman), Michael A Quinn, and R Peter Campbell all non 
executive directors.

Details of these directors’ attendance at nomination committee 
meetings are set out in the directors’ report on page 13.

The nomination committee operates in accordance with its charter 
which is available on the Company website. The nomination 
committee assists the board to discharge its responsibilities 
with regards to overseeing the composition of the board and 
competencies of directors together with developing procedures to 
asses the performance of directors. Further, advise the board on 
appointment and evaluation of Managing Director and to develop 
succession plans for the board, Managing Director and senior 
management.

28  QRxPharma  Annual Report 2008

(cid:129)  periodically assessing the appropriate mix of skills, experience  
  and expertise required on the board and assessing the extent to  

required which skills are represented on the board

(cid:129)  establishing processes for identifi cation of suitable candidates 

for appointment to the board

(cid:129)  monitoring the length of service of current board members,  
  considering succession planning issues and identifying the  

likely order of retirement by rotation of non executive directors

(cid:129)  establishing processes for the review of the performance  
  of individual non executive directors, the board and board  
  committees.

Whilst the nominations committee may recommend new director 
candidates, it is the full board that is responsible for the actual 
appointment of new directors and any candidate appointed 
must stand for election at the next annual general meeting of the 
company. The committee’s nomination of existing directors for 
reappointment is also not automatic and is contingent on their past 
performance, contribution to the Company and the current and 
future needs of the board and Company.

Remuneration committee

The remuneration committee is currently comprised of Peter C 
Farrell (Chairman), Michael A Quinn, both non executive directors 
and John W Holaday, the Managing Director.

Details of these directors’ attendance at remuneration committee 
meetings are set out in the directors’ report on page 13.

The remuneration committee operates in accordance with 
its charter which is available on the Company website. The 
remuneration committee assists the board to discharge 
its responsibilities to attract and retain senior executives 
and directors who will create value for shareholders. The 
remuneration committee advises the board on remuneration and 
incentive policies and practices generally, and makes specifi c 
recommendations on remuneration packages and other terms of 
employment for senior executives and directors.

 
 
 
 
 
 
 
 
The main responsibilities of the committee include:

(cid:129)  assisting the board in setting the executive remuneration policy  
inclusive of the operation of the Company’s employee share  

  option plan

(cid:129)  overseeing the adequacy of the Company’s fi nancial controls  
  and systems

(cid:129)  overseeing the process of identifi cation and management of  
  business, fi nancial and commercial risks.

(cid:129)  making recommendations to the board for reviewing and  
  approving the remuneration of executive directors

In fulfi lling its responsibilities, the audit committee:

(cid:129)  reviewing and approving the remuneration of senior executives  
  as defi ned by the board from time to time.

Each member of the senior executive team signs a formal 
employment contract at the time of their appointment covering a 
range of matters including their duties, rights, responsibilities and 
any entitlements on termination. 

Further information on directors’ and executives’ remuneration is 
set out in the directors’ report under the heading ‘’Remuneration 
report’’.

Audit and risk committee

The audit and risk committee is currently comprised of R Peter 
Campbell (Chairman) and Michael A Quinn, both non executive 
directors.

Details of these directors’ qualifi cations and attendance at audit 
committee meetings are set out in the directors’ report on pages 
10 - 13.

The audit committee has appropriate fi nancial expertise and 
all members are fi nancially literate and have an appropriate 
understanding of the industry in which the Group operates.

The audit committee operates in accordance with a charter which 
is available on the company website. The audit and risk committee 
assist the board to discharge its responsibilities relating to the 
effectiveness of the control environment and risk management 
framework in the areas of operational and balance sheet risk, 
legal/regulatory compliance and fi nancial reporting, together with 
the effectiveness and independence of the external audit process. 

The main responsibilities of the committee include:

(cid:129)  overseeing the Company’s relationship with the external   
   auditor (including forming a policy on the provision of non  
   audit services and the rotation of external audit personnel on  
   a regular basis) and the external audit function in general. This  
   includes recommending to the board the appointment, removal  
   and remuneration of the external auditors, and reviewing the  
   terms of their engagement, the scope and quality of the audit and  
   assess performance

(cid:129)  receives regular reports from management and external auditors

(cid:129)  meets with the external auditors at least twice a year, or more  

frequently if necessary

(cid:129)  reviews any signifi cant disagreements between the auditors and  
  management, irrespective of whether they have been resolved

(cid:129)  provides the external auditors with a clear line of direct   
  communication at any time to the audit committee.

 The audit committee has authority, within the scope of its 
responsibilities, to seek any information it requires from any 
employee or external party.

External auditors

The Company and audit committee policy is to appoint external 
auditors who clearly demonstrate quality and independence. 
PricewaterhouseCoopers is the incumbent external auditor. It 
is PricewaterhouseCoopers policy to rotate audit engagement 
partners on listed companies at least every fi ve years.

An analysis of fees paid to the external auditors, including a break 
down of fees for non audit services, is provided in the directors’ 
report and in note 21 to the fi nancial statements. It is the policy 
of the external auditors to provide an annual declaration of their 
independence to the audit committee.

Risk assessment and management

The board, through the audit committee, is responsible for 
ensuring there is an adequate framework in relation to risk 
management, compliance and internal control systems. In 
summary, the framework is designed to ensure strategic, 
operational, legal, reputation and fi nancial risks are identifi ed, 
assessed, effectively and effi ciently managed and monitored to 
enable achievement of the Group’s business objectives.

Code of Conduct

Over the past year the board has conducted the affairs of the 
Company in accordance with principles of good corporate 
governance and has required that at all times all Group personnel 
act with the utmost integrity, objectivity and in compliance with the 
letter and the spirit of the law and Group policies.

(cid:129)  overseeing the adequacy of the control processes in place in  
relation to the preparation of fi nancial statements and reports

The Company is developing a Code of Conduct to guide the 
board, individual directors and senior management as to the 

www.qrxpharma.com  29

 
 
 
CORPORATE GOVERNANCE STATEMENT (CONTINUED)

practices necessary to maintain confi dence in the Group’s integrity 
with key stakeholders and the wider community together with the 
responsibility and accountability of individuals for reporting and 
investigating reports of unethical practices.

The Company maintains a Securities Trading Policy which is 
available on the company website. All directors, offi cers and 
employees are prohibited from dealing in any QRxPharma Limited 
securities, except while not in possession of unpublished price 
sensitive information. It is also contrary to the Company’s policy 
for directors, offi cers and employees to be engaged in short 
term trading of the Company’s securities. Directors, offi cers and 
employees may only deal in the Company’s securities during a 
specified period of 45 days after the release of the Company’s 
results or after the AGM. Directors must obtain the approval of the 
Chairman and employees the approval of the Company Secretary 
prior to dealing in the Company’s securities outside those periods.

Continuous disclosure and shareholder communication

In fulfi lling its responsibilities on continuous disclosure of any 
information concerning the Group that a reasonable person would 
expect to have a material effect on the price of the company’s 
securities the Company is committed to:

(cid:129)  ensuring that shareholders and the fi nancial markets are  
  provided with timely disclosure about its activities

(cid:129)  fully complying with continuous disclosure obligations contained  

in applicable ASX listing rules and the Corporations Act

(cid:129)  ensuring that all investors have equal and timely access to  
  material information concerning the Group.

The Company has detailed this commitment in a Shareholder 
Communication Policy which is available on the Company website.

The Company Secretary has been nominated as the person 
responsible for communications with the ASX. This role includes 
responsibility for ensuring compliance with the continuous 
disclosure requirements in the ASX Listing Rules and overseeing 
and co ordinating information disclosure to the ASX, analysts, 
brokers, shareholders, the media and the public.

The Company website provides general information and reports 
on the Group, inclusive of ASX announcements, investor 
presentations, and a link to ASX website which displays the share 
price, share price movements and other market information. 

30  QRxPharma  Annual Report 2008

 
 
FINANCIAL REPORT

This fi nancial report covers both QRxPharma Limited as an 
individual entity and the consolidated entity consisting of 
QRxPharma Limited and its subsidiaries.  The fi nancial report is 
presented in the Australian currency.

QRxPharma Limited is a company limited by shares, incorporated 
and domiciled in Australia.  Its registered offi ce and principal place 
of business is:

QRxPharma Limited
Level 1
194 Miller St
North Sydney  NSW  2060.

A description of the nature of the consolidated entity’s operations 
and its principal activities is included in the CEOs review on pages 
4-7 and in the directors’ report on pages 8-24, both of which are 
not part of this fi nancial report.

The fi nancial report was authorised for issue by the directors on 
20 August 2008. The company has the power to amend and 
reissue the fi nancial report.

Through the use of the internet, we have ensured that our 
corporate reporting is timely, complete, and available globally at 
minimum cost to the company.  All press releases, fi nancial reports 
and other information are available on our website:

 www.qrxpharma.com

Income statements 

Balance sheets 

Statements of changes in equity 

Cash fl ow statements 

Notes to the fi nancial statements   

Directors’ declaration 

Independent auditor’s report to the members 

Shareholder information 

32

33 

34

35

36

73

74

77

www.qrxpharma.com  31

 
 
 
 
 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
INCOME STATEMENTS 
FOR THE YEAR ENDED 30 JUNE 2008

Revenue from continuing operations
Other income
Research and development
Employee benefi ts expense
Depreciation and amortisation
Finance costs
Other expenses
Net foreign exchange loss
Impairment of fi nancial asset
Impairment of intangible asset

Loss before income tax

Income tax benefi t

Loss from continuing operations

Loss for the year

Notes

5
6
7

7

14
16

8

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

2,009
-
(12,708)
(5,298)
(822)
 -
(2,662)
(2,618)
  -
(14,628)

(36,727)

125

(36,602)

(36,602)

304
4,951
(2,376)
(690)
(83)
(1,497)
(1,090)
(272)
-

(753)

348

(405)

(405)

2,009
515
(13,970)
(2,838)
(16)
-  
(3,048)
(2,648)
(17,117)
-

(37,113)

125

(36,988)

(36,988)

304
4,951
(2,376)
(690)
(11)
(1,497)
(1,090)           
(272)
-
- 

(681)

348

(333)

(333)

Earnings per share for loss attributable 

Cents

Cents

Basic loss per share

Diluted loss per share

27

27

(48.8)

(48.8)

(2.8)

(2.8)

The above income statements should be read in conjunction with the accompanying notes. 

32  QRxPharma  Annual Report 2008

QRxPHARMA LIMITED ABN 16 102 254 151
BALANCE SHEETS
AS AT 30 JUNE 2008

ASSETS

Current assets

Cash and cash equivalents
Trade and other receivables
Other fi nancial assets at fair value through 
profi t or loss
Held-to-maturity investments
Other current assets

Total current assets

Non-current assets

Other fi nancial assets at fair value through 
profi t or loss
Other fi nancial assets
Property, plant and equipment
Intangible assets

Total non-current assets

Total assets

LIABILITIES

Current liabilities

Trade and other payables
Other fi nancial liabilities at fair value through 
profi t or loss

Total current liabilities

Total liabilities

Net assets

EQUITY

Contributed equity
Reserves
Accumulated losses

Total equity

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

Notes

9
10
11

12
13

11

14
15
16

17
11

29,672
158
-

        35,690
           136
374

29,583
135
-

-
           458

10,491
           118

-
           119

30,288

46,809

29,837

35,690
           136
374

10,491
              -

46,691

-

           548

-

           548

            -
73
-

-
25
        15,430

73

        16,003

2,605
37
-

2,642

30,361

62,812

32,479

        15,620
            25
-

16,193

62,884

2,024
              -

678
           154

2,024

2,024

832

832

4,169
-

4,169

4,169

706
           154

860

860

28,337

61,980

28,310

62,024

18
19(a)
19(b)

79,694
3,584
(54,941)

28,337

79,932
387
(18,339)

61,980

79,694
3,899
(55,283)

28,310

79,932
387
(18,295)

62,024

The above balance sheets should be read in conjunction with the accompanying notes.

www.qrxpharma.com  33

 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
STATEMENTS OF CHANGES IN EQUITY
FOR THE YEAR ENDED 30 JUNE 2008

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

Notes

Total equity / (defi ciency in capital) at the 
beginning of the fi nancial year

61,980

(17,103)

62,024

(17,131)

Loss for the year

(36,602)

(405)

(36,988)

(333)

Transactions with equity holders in their 
capacity as equity holders:
Contributions of equity, net of transaction costs
Employee shares and share options
Foreign currency translation

18
19
19

(238)
3,512
          (315)

79,263
225             
-

(238)
3,512
              -

2,959

79,488

3,274

Total equity at the end of the fi nancial year 

28,337  

61,980

28,310

The above statements of changes in equity should be read in conjunction with the accompanying notes.

79,263
225
             -

79,488

62,024

34  QRxPharma  Annual Report 2008

 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
CASH FLOW STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2008

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

Notes

Cash fl ows from operating activities

Payments to suppliers and employees (inclusive of goods 
and services tax)

Interest received

Income tax R&D receipt

Payment for fi nancial instrument

Net cash outfl ow from operating activities

Cash fl ows from investing activities

Payments in relation to purchase of subsidiary
Payments for property, plant and equipment
Payments for intellectual property
Payments for shares issued in subsidiary
Proceeds (payments) for held-to-maturity investments

8

26

14

(15,822)

        (2,004)           

(12,669)

(1,878)

1,550

           248

125

           348

1,550

125

248

348

              -

        (1,127)

              -

        (1,127)

(14,147)

        (2,535)

(10,994)

        (2,409)

-
(68)
-
-
10,846

  (220)
           (18)
          (274)
-
       (10,491)

-
(28)
-
      (3,252)
10,846

              (220)
           (18)
-
          (400)
       (10,491)

Net cash infl ow / (outfl ow) from investing activities

10,778

       (11,003)

7,566

       (11,129)

Cash fl ows from fi nancing activities

Proceeds from issues of shares 
Payments made in relation to IPO
Proceeds from borrowings

Net cash infl ow / (outfl ow) from fi nancing activities

-
(31)
-

(31)

51,726
        (3,699)
1,225

49,252  

-
(31)
-

(31)

51,726
      (3,699)
1,224

49,251

Net (decrease) / increase in cash and cash equivalents

(3,400)

35,713

(3,459)

35,713

Cash and cash equivalents at the beginning 
of the fi nancial year
Effects of exchange rate changes on cash 
and cash equivalents

Cash and cash equivalents at end of year

9

35,690

(2,618)

29,672

249

(272)

35,690

(2,648)

35,690

     29,583

249

  (272)

35,690

The above cash fl ow statements should be read in conjunction with the accompanying notes.

www.qrxpharma.com  35

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
NOTES TO THE FINANCIAL STATEMENTS

1    Summary of signifi cant accounting policies   

2    Financial risk management 

3    Critical accounting estimates and judgements 

4    Segment information 

5    Revenue   

6    Other income   

7    Expenses  

8   

Income tax benefi t 

9    Current assets – Cash and cash equivalents  

10  Current assets – Trade and other receivables 

11  Other fi nancial assets and liabilities at 
fair value through profi t or loss 

12  Current assets – Held-to-maturity investments 

13  Current assets – Other current assets 

14  Non current assets – Other fi nancial assets   

37

44

48

49

49

49

50

51

52

52

53

54

54

54

15  Non current assets – Property, plant and equipment  55

16  Non current assets – Intangible assets 

17  Current liabilities – Trade and other payables  

18  Contributed equity 

19  Reserves and accumulated losses  

20  Key management personnel disclosures 

21  Remuneration of auditors 

22  Contingencies  

23  Commitments  

24  Related party transactions 

25  Subsidiaries  

26  Reconciliation of profi t after income tax 

to net cash infl ow from operating activities 

27  Loss per share 

28  Share-based payments   

29  Events occurring after the balance sheet date 

56

57

58

60

61

65

65

65

66

67

67

68

69

72

36  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 30 JUNE 2008

1   SUMMARY OF SIGNIFICANT  
    ACCOUNTING POLICIES

The principal accounting policies adopted in the preparation of 
the fi nancial report are set out below.  These policies have been 
consistently applied to all the years presented, unless otherwise 
stated.  The fi nancial report includes separate fi nancial statements 
for QRxPharma Limited as an individual entity and the consolidated 
entity consisting of QRxPharma Limited and its subsidiaries.

(A)  BASIS OF PREPARATION

This general purpose fi nancial report has been prepared in 
accordance with Australian Accounting Standards, other 
authoritative pronouncements of the Australian Accounting 
Standards Board, Urgent Issues Group Interpretations and the 
Corporations Act 2001.

Compliance with IFRS

Australian Accounting Standards include Australian equivalents to 
International Financial Reporting Standards (AIFRS).  Compliance 
with AIFRS ensures the fi nancial report of QRxPharma Limited 
complies with International Financial Reporting Standards (IFRS). 

Historical cost convention

These fi nancial statements have been prepared under the historical 
cost convention, as modifi ed by the revaluation of fi nancial assets 
and liabilities (including derivative instruments) at fair value through 
profi t or loss.

Critical accounting estimates

The preparation of fi nancial statements in conformity with 
AIFRS requires the use of certain critical accounting estimates. 
It also requires management to exercise its judgment in the 
process of applying the Group’s accounting policies. The areas 
involving a higher degree of judgment or complexity, or areas 
where assumptions and estimates are signifi cant to the fi nancial 
statements, are disclosed in note 3.

(B)  GOING CONCERN  

The Group has experienced signifi cant recurring operating 
losses and negative cash fl ows from operating activities since 
its inception. During the year ended 30 June 2007, the Group 
completed an Initial Public Offering (IPO) raising $50 million (before 
transaction costs of $3.7 million) in conjunction with the admission 
of the Company on the Australian Securities Exchange (ASX).  At 
30 June 2008, the Group holds cash and cash equivalents of 
$29.7 million.

The directors have considered the signifi cance and possible 
effects of these circumstances in order to determine the suitability 
of adopting the going concern basis for the preparation of this 
fi nancial report.

Having carefully assessed the fi nancial and operating implications 
of the above matters, the directors consider that the Group will 
be able to pay its debts as and when they fall due for at least 12 
months following the date of these fi nancial statements and that it 
is appropriate for the accounts to be prepared on a going concern 
basis.

(C)  PRINCIPLES OF CONSOLIDATION

The consolidated fi nancial statements incorporate the assets and 
liabilities of all subsidiaries of QRxPharma Limited (‘’company’’ 
or ‘’parent entity’’) as at 30 June 2008 and the results of all 
subsidiaries for the year then ended.  QRxPharma Limited and its 
subsidiaries together are referred to in this fi nancial report as the 
Group or the consolidated entity.

Subsidiaries are all those entities (including special purpose entities) 
over which the Group has the power to govern the fi nancial and 
operating policies, generally accompanying a shareholding of 
more than one half of the voting rights.  The existence and effect of 
potential voting rights that are currently exercisable or convertible 
are considered when assessing whether the Group controls 
another entity.

Subsidiaries are fully consolidated from the date on which control is 
transferred to the Group.  They are de consolidated from the date 
that control ceases.

Intercompany transactions, balances and unrealised gains on 
transactions between Group companies are eliminated.  Unrealised 
losses are also eliminated unless the transaction provides evidence 
of the impairment of the asset transferred.  Accounting policies 
of subsidiaries have been changed where necessary to ensure 
consistency with the policies adopted by the Group.

(D)  SEGMENT REPORTING

A business segment is identifi ed for a group of assets and 
operations engaged in providing products or services that are 
subject to risks and returns that are different to those of other 
business segments.  A geographical segment is identifi ed when 
products or services are provided within a particular economic 
environment subject to risks and returns that are different from 
those of segments operating in other economic environments.

(E)  FOREIGN CURRENCY TRANSLATION

(i)   Functional and presentation currency 

Items included in the fi nancial statements of each of the Group’s 
entities are measured using the currency of the primary economic 
environment in which the entity operates (‘the functional currency’).  
The consolidated fi nancial statements are presented in Australian 
dollars, which is QRxPharma Limited’s functional and presentation 
currency.

www.qrxpharma.com  37

 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

1   SUMMARY OF SIGNIFICANT  
    ACCOUNTING POLICIES (CONTINUED)

national income tax rate for each jurisdiction adjusted by changes 
in deferred tax assets and liabilities attributable to temporary 
differences and to unused tax losses.

(ii)  Transactions and balances

Foreign currency transactions are translated into the functional 
currency using the exchange rates prevailing at the dates of the 
transactions.  Foreign exchange gains and losses resulting from 
the settlement of such transactions and from the translation at year 
end exchange rates of monetary assets and liabilities denominated 
in foreign currencies are recognised in the income statement, 
except when they are deferred in equity as qualifying cash fl ow 
hedges and qualifying net investment hedges or are attributable to 
part of the net investment in a foreign operation. 

(iii)  Group companies

The results and fi nancial position of all the Group entities (none of 
which has the currency of a hyperinfl ationary economy) that have 
a functional currency different from the presentation currency are 
translated into the presentation currency as follows:

(cid:129)  assets and liabilities for each balance sheet presented are  

translated at the closing rate at the date of that balance sheet

(cid:129)  income and expenses for each income statement are translated  
  at average exchange rates (unless this is not a reasonable  
  approximation of the cumulative effect of the rates prevailing on  
the transaction dates, in which case income and expenses are  
translated at the dates of the transactions), and

(cid:129)  all resulting exchange differences are recognised as a separate  
  component of equity.

On consolidation, exchange differences arising from the translation 
of any net investment in foreign entities, and of borrowings 
and other fi nancial instruments designated as hedges of such 
investments, are taken to shareholders’ equity.  When a foreign 
operation is sold or any borrowings forming part of the net 
investment are repaid, a proportionate share of such exchange 
differences are recognised in the income statement as part of the 
gain or loss on sale where applicable.

Goodwill and fair value adjustments arising on the acquisition of 
a foreign entity are treated as assets and liabilities of the foreign 
entities and translated at the closing rate.

(F)  REVENUE RECOGNITION

Interest income

Interest income is recognised on a time proportion basis using the 
effective interest method.

(G)  INCOME TAX

The income tax expense or revenue for the period is the tax 
payable on the current period’s taxable income based on the 

38  QRxPharma  Annual Report 2008

Deferred income tax is provided in full, using the liability method, on 
temporary differences arising between the tax bases of assets and 
liabilities and their carrying amounts in the consolidated fi nancial 
statements.  However, the deferred income tax is not accounted 
for if it arises from initial recognition of an asset or liability in a 
transaction other than a business combination that at the time of 
the transaction affects neither accounting nor taxable profi t or loss.  
Deferred income tax is determined using tax rates (and laws) that 
have been enacted or substantially enacted by the balance sheet 
date and are expected to apply when the related deferred income 
tax asset is realised or the deferred income tax liability is settled.

Deferred tax assets are recognised for deductible temporary 
differences and unused tax losses only if it is probable that future 
taxable amounts will be available to utilise those temporary 
differences and losses.

Deferred tax liabilities and assets are not recognised for temporary 
differences between the carrying amount and tax bases of 
investments in controlled entities where the parent entity is able to 
control the timing of the reversal of the temporary differences and 
it is probable that the differences will not reverse in the foreseeable 
future.

Tax consolidation legislation

QRxPharma Limited and its wholly owned Australian controlled 
entities have implemented the tax consolidation legislation.

The head entity, QRxPharma Limited, and the controlled entities 
in the tax consolidated group account for their own current and 
deferred tax amounts.  These tax amounts are measured as if each 
entity in the tax consolidated group continues to be a stand alone 
taxpayer in its own right.

(H)  BUSINESS COMBINATIONS

The purchase method of accounting is used to account for all 
business combinations, including business combinations involving 
entities or businesses under common control, regardless of 
whether equity instruments or other assets are acquired.  Cost is 
measured as the fair value of the assets given, shares issued or 
liabilities incurred or assumed at the date of exchange plus costs 
directly attributable to the acquisition.  Where equity instruments 
are issued in an acquisition, the fair value of the instruments is their 
published market price as at the date of exchange unless, in rare 
circumstances, it can be demonstrated that the published price 
at the date of exchange is an unreliable indicator of fair value and 
that other evidence and valuation methods provide a more reliable 
measure of fair value.  Transaction costs arising on the issue of 
equity instruments are recognised directly in equity.

 
 
 
 
(I)   IMPAIRMENT OF ASSETS

(ii)  Loans and receivables

Assets are reviewed for impairment whenever events or changes 
in circumstances indicate that the carrying amount may not be 
recoverable. An impairment loss is recognised for the amount 
by which the asset’s carrying amount exceeds its recoverable 
amount. The recoverable amount is the higher of an asset’s fair 
value less costs to sell and value in use. For the purposes of 
assessing impairment, assets are grouped at the lowest levels 
for which there are separately identifi able cash infl ows which 
are largely independent of the cash infl ows from other assets or 
groups of assets (cash generating units).  Non fi nancial assets 
other than goodwill that suffered an impairment are reviewed for 
possible reversal of the impairment at each reporting date.

(J)  GRANT INCOME

Government grants are recognised as income over the periods 
necessary to match them with the related costs which they are 
intended to compensate, on a systematic basis.

(K)  CASH AND CASH EQUIVALENTS

For cash fl ow statement presentation purposes, cash and cash 
equivalents includes cash on hand, deposits held at call with 
fi nancial institutions, other short term, highly liquid investments 
with original maturities of three months or less that are readily 
convertible to known amounts of cash and which are subject to an 
insignifi cant risk of changes in value, and bank overdrafts.  Bank 
overdrafts are shown within borrowings in current liabilities on the 
balance sheet.

Loans and receivables are non derivative fi nancial assets with 
fi xed or determinable payments that are not quoted in an active 
market.  They are included in current assets, except for those with 
maturities greater than 12 months after the balance sheet date 
which are classifi ed as non current assets.  Loans and receivables 
are included in trade and other receivables in the balance sheet 
(note 10).

(iii)  Held-to-maturity investments

Held-to-maturity investments are non derivative fi nancial assets 
with fi xed or determinable payments and fi xed maturities that the 
Group’s management has the positive intention and ability to hold 
to maturity.  If the Group were to sell other than an insignifi cant 
amount of held-to-maturity fi nancial assets, the whole category 
would be tainted and reclassifi ed as available for sale.  Held-to-
maturity fi nancial assets are included in non current assets, except 
for those with maturities less than 12 months from the reporting 
date, which are classifi ed as current assets.

Recognition and derecognition

Financial assets carried at fair value through profi t or loss are initially 
recognised at fair value and transaction costs are expensed in the 
income statement. Financial assets are derecognised when the 
rights to receive cash fl ows from the fi nancial assets have expired or 
have been transferred and the Group has transferred substantially 
all the risks and rewards of ownership.

Subsequent measurement

(L)  INVESTMENTS AND OTHER FINANCIAL 
ASSETS

Loans and receivables and held-to-maturity investments are carried 
at amortised cost using the effective interest method.

Classifi cation

Fair value

The Group classifi es its investments in the following categories: 
fi nancial assets at fair value through profi t or loss, loans and 
receivables and held-to-maturity investments.  The classifi cation 
depends on the purpose for which the investments were acquired.  
Management determines the classifi cation of its investments at 
initial recognition and, in the case of assets classifi ed as held-to-
maturity, re evaluates this designation at each reporting date.

(i)   Financial assets at fair value through profi t or loss

Financial assets at fair value through profi t or loss are fi nancial 
assets held for trading.  A fi nancial asset is classifi ed in this 
category if acquired principally for the purpose of selling in the 
short term.  Derivatives are classifi ed as held for trading unless 
they are designated as hedges. 

The fair values of option agreements are based on current market 
prices. 

(M) PROPERTY, PLANT AND EQUIPMENT

Depreciation on plant and equipment is calculated using the 
straight line method to allocate their cost, net of their residual 
values, over their estimated useful lives, as follows:

– Plant and equipment 

4 years

The assets’ residual values and useful lives are reviewed, and 
adjusted if appropriate, at each balance sheet date.

An asset’s carrying amount is written down immediately to its 
recoverable amount if the asset’s carrying amount is greater than its 
estimated recoverable amount (note 1(i)).

www.qrxpharma.com  39

QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

1   SUMMARY OF SIGNIFICANT  
    ACCOUNTING POLICIES (CONTINUED) 

(N)  INTANGIBLE ASSETS

(i)    Intellectual property

Costs incurred in acquiring intellectual property are capitalized and 
amortised on a straight line basis of the period of the expected 
benefi t. 

Costs include only those costs directly attributable to the 
acquisition of the intellectual property.

An asset’s carrying amount is written down immediately to its 
recoverable amount if the asset’s carrying amount is greater than 
its estimated recoverable amount (note 1(i)).

(ii)   Research and development

Research expenditure on internal development projects is 
recognised as an expense as incurred.  Costs incurred on 
development projects (relating to the design and testing of new or 
improved products) are recognised as intangible assets when it is 
probable that the project will, after considering its commercial and 
technical feasibility, be completed and generate future economic 
benefi ts and its costs can be measured reliably.  The expenditure 
capitalised comprises all directly attributable costs, including 
costs of materials, services, direct labour and an appropriate 
proportion of overheads.  Other development expenditures that do 
not meet these criteria are recognised as an expense as incurred.  
Development costs previously recognised as an expense are 
not recognised as an asset in a subsequent period. Capitalised 
development costs are recorded as intangible assets and 
amortised from the point at which the asset is ready for use on a 
straight line basis over its useful life, which varies from 3 to 5 years.

(O)  TRADE AND OTHER PAYABLES

These amounts represent liabilities for goods and services 
provided to the Group prior to the end of fi nancial year which are 
unpaid.  The amounts are unsecured and are usually paid within 
30 days of recognition.

(P)  BORROWINGS

Non redeemable preference shares are classifi ed as liabilities. 
The accrued liabilities on preference shares are recognised in the 
income statement as interest expense.

Borrowings are classifi ed as current liabilities unless the Group has 
an unconditional right to defer settlement of the liability for at least 
12 months after the balance sheet date.

(Q)  BORROWING COSTS

Borrowing costs are recognised as expenses in the period in which 
they are incurred. Borrowing costs include interest paid or payable 
on convertible notes.

(R)  EMPLOYEE BENEFITS

(i) Wages and salaries and annual leave

Liabilities for wages and salaries, including non monetary benefi ts 
and annual leave expected to be settled within 12 months of the 
reporting date are recognised in other payables in respect of 
employees’ services up to the reporting date and are measured at 
the amounts expected to be paid when the liabilities are settled.

(ii)  Long service leave

The liability for long service leave is recognised in the provision for 
employee benefi ts and measured as the present value of expected 
future payments to be made in respect of services provided by 
employees up to the reporting date.  Consideration is given to 
expected future wage and salary levels, experience of employee 
departures and periods of service.  Expected future payments are 
discounted using market yields at the reporting date on national 
government bonds with terms to maturity and currency that match, 
as closely as possible, the estimated future cash outfl ows.

(iii)  Retirement benefi t obligations

The Group does not maintain a Group superannuation plan. The 
Group makes fi xed percentage contributions for all Australian 
resident employees to complying third party superannuation 
funds and for US resident employees to complying pension funds. 
The Group’s legal or constructive obligation is limited to these 
contributions.

Contributions to complying third party superannuation funds and 
pension plans are recognised as an expense as they become 
payable.  Prepaid contributions are recognised as an asset to the 
extent that a cash refund or a reduction in the future payments is 
available.

(iv)  Share-based payments

Share-based compensation benefi ts are provided to employees via 
the QRxPharma Limited Employee Share Option Plan.  Information 
relating to this scheme is set out in note 28.

The fair value of options granted under the QRxPharma Limited 
Employee Share Option Plan is recognised as an employee benefi t 
expense with a corresponding increase in equity.  The fair value 
is measured at grant date and recognised over the period during 
which the employees become unconditionally entitled to the options.

Convertible notes and accrued interest are recognised as a liability. 
The liability is included in borrowings until the conversion or 
maturity of the notes. 

The fair value at grant date is independently determined using 
a Black Scholes option pricing model that takes into account 

40  QRxPharma  Annual Report 2008

 
the exercise price, the term of the option, the impact of dilution, 
the share price at grant date and expected price volatility of the 
underlying share, the expected dividend yield and the risk free 
interest rate for the term of the option.

The fair value of the options granted is adjusted to refl ect 
market vesting conditions, but excludes the impact of any non 
market vesting conditions (for example, profi tability and sales 
growth targets).  Non market vesting conditions are included 
in assumptions about the number of options that are expected 
to become exercisable.  At each balance sheet date, the entity 
revises its estimate of the number of options that are expected to 
become exercisable. The employee benefi t expense recognised 
each period takes into account the most recent estimate.  The 
impact of the revision to original estimates, if any, is recognised in 
the income statement with a corresponding adjustment to equity.

Upon the exercise of options, the balance of the share-based 
payments reserve relating to those options is transferred to share 
capital and the proceeds received, net of any directly attributable 
transaction costs, are credited to share capital.

(v)  Bonus plans

The Group recognises a liability and an expense for bonuses in 
accordance with the terms of employment contracts.  The Group 
recognises a provision where contractually obliged or where there 
is a past practice that has created a constructive obligation.

(vi)  Employee benefi t on-costs

Employee benefi t on-costs, including payroll tax, are recognised 
and included in the employee benefi t liabilities and costs when the 
employee benefi ts to which they relate are recognised.

(S)  CONTRIBUTED EQUITY

Ordinary shares are classifi ed as equity.  

Incremental costs directly attributable to the issue of new shares 
or options are shown in equity as a deduction, net of tax, from 
the proceeds.  Incremental costs directly attributable to the issue 
of new shares or options for the acquisition of a business are not 
included in the cost of the acquisition as part of the purchase 
consideration.

(T)  EARNINGS PER SHARE

(i) Basic earnings per share

(ii)  Diluted earnings per share

Diluted earnings per share adjusts the fi gures used in the 
determination of basic earnings per share to take into account 
the after income tax effect of interest and other fi nancing costs 
associated with dilutive potential ordinary shares and the weighted 
average number of shares assumed to have been issued for no 
consideration in relation to dilutive potential ordinary shares.

(U)  DERIVATIVES

Derivatives that do not qualify for hedge accounting

Derivatives are initially recognised at fair value on the date a 
derivative contract is entered into and are subsequently remeasured 
to their fair value at each reporting date. Changes in the fair value of 
any derivative instrument that does not qualify for hedge accounting 
are recognised immediately in the income statement and are 
included in other income or other expenses.

(V)  FAIR VALUE ESTIMATION

The fair value of fi nancial assets and fi nancial liabilities must be 
estimated for recognition and measurement or for disclosure 
purposes.

The fair value of fi nancial instruments traded in active markets is 
based on quoted market prices at the balance sheet date.  The 
quoted market price used for fi nancial assets held by the Group is 
the current bid price.

(W) GOODS AND SERVICES TAX (GST)

Revenues, expenses and assets are recognised net of the amount 
of associated GST, unless the GST incurred is not recoverable from 
the taxation authority.  In this case it is recognised as part of the 
cost of acquisition of the asset or as part of the expense.

Receivables and payables are stated inclusive of the amount of 
GST receivable or payable.  The net amount of GST recoverable 
from, or payable to, the taxation authority is included with other 
receivables or payables in the balance sheet.

Cash fl ows are presented on a gross basis.  The GST components 
of cash fl ows arising from investing or fi nancing activities which are 
recoverable from, or payable to the taxation authority, are presented 
as operating cash fl ow.

(X)   ROUNDING OF AMOUNTS

Basic earnings per share is calculated by dividing the profi t 
attributable to equity holders of the company, excluding any costs 
of servicing equity other than ordinary shares, by the weighted 
average number of ordinary shares outstanding during the fi nancial 
year, adjusted for bonus elements in ordinary shares issued during 
the year.

The company is a kind referred to in Class order 98/100, issued by 
the Australian Securities and Investments Commission, relating to 
the “rounding off” of amounts in the fi nancial report.  Amounts in 
the fi nancial report have been rounded off in accordance with that 
Class Order to the nearest thousand dollars, or in certain cases, the 
nearest dollar.

www.qrxpharma.com  41

QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

1   SUMMARY OF SIGNIFICANT  
    ACCOUNTING POLICIES (CONTINUED) 

(Y)  NEW ACCOUNTING STANDARDS AND 
INTERPRETATIONS

Certain new accounting standards and interpretations have been 
published that are not mandatory for 30 June 2008 reporting 
periods.  The Group’s assessment of the impact of these new 
standards and interpretations is set out below.

AASB 8 Operating Segments and AASB 2007-3 
Amendments to Australian Accounting Standards 
arising from AASB 8

AASB 8 and AASB 2007-3 are effective for annual reporting 
periods commencing on or after 1 January 2009.  AASB 8 will 
result in a signifi cant change in the approach to segment reporting, 
as it requires adoption of a “management approach” to reporting 
on the fi nancial performance.  The information being reported 
will be based on what the key decision-makers use internally for 
evaluating segment performance and deciding how to allocate 
resources to operating segments.  The Group will adopt AASB 8 
for the reporting period commencing on 1 July 2009.  Application 
of AASB 8 may result in different segments, segment results and 
different type of information being reported in the segment note of 
the fi nancial report.  However, it will not affect any of the amounts 
recognised in the fi nancial statements.

AASB-I 13 Customer Loyalty Programmes 

AASB-I 13 is applicable to annual reporting periods commencing 
on or after 1 July 2008.  It provides guidance on the accounting for 
customer loyalty programmes and requires that the fair value of the 
consideration received/receivable in respect of a sale transaction 
is allocated between the award credits and the other components 
of the sale.   The Group does not operate any customer loyalty 
programmes.  AASB-I 13 will therefore have no impact on the 
Group’s fi nancial statements.

Revised AASB 101 Presentation of Financial 
Statements and AASB 2007-8 Amendments to 
Australian Accounting Standards arising from AASB 101

The revised AASB 101 that was issued in September 2007 is 
applicable for annual reporting periods beginning on or after 
1 January 2009.  It requires the presentation of a statement of 
comprehensive income and makes changes to the statement of 
changes in equity but will not affect any of the amounts recognised 
in the fi nancial statements.  

AASB 2008-1 Amendments to Australian Accounting 
Standard – Share-based Payments: Vesting Conditions 
and Cancellations

AASB 2008-1 was issued in February 2008 and will become 
applicable for annual reporting periods beginning on or after 
1 January 2009.  The revised standard clarifi es that vesting 
conditions are service conditions and performance conditions only 
and that other features of a share-based payment are not vesting 
conditions.  It also specifi es that all cancellations, whether by the 
entity or by other parties, should receive the same accounting 
treatment.  The Group will apply the revised standard from 1 July 
2009, but it is not expected to affect the accounting for the Group’s 
share-based payments.

AASB 2008-2 Amendments to Australian Accounting 
Standards – Puttable Financial Instruments and 
Obligations Arising on Liquidation [AASB 7, AASB 101, 
AASB 132, AASB 139 and Interpretation 2]

The amendments made by AASB 2008-2 in March 2008 relate 
to puttable fi nancial instruments and instruments that require the 
entity to pay the holder a pro-rata share of the entity’s net assets 
on liquidation.  The revised standards have to be applied from 1 
January 2009.  Under the revised rules, the relevant instruments 
will be classifi ed as equity if certain conditions are satisfi ed.  As the 
Group has not issued any such instruments, the amendments will 
not have any effect on the Group’s or the parent entity’s fi nancial 
statements.

Revised AASB 3 Business Combinations, AASB 127 
Consolidated and Separate Financial Statements and 
AASB 2008-3 Amendments to Australian Accounting 
Standards arising from AASB 3 and AASB 127

Revised accounting standards for business combinations and 
consolidated fi nancial statements were issued in March 2008 and 
are operative for annual reporting periods beginning on or after 
1 July 2009, but may applied earlier.  The Group will apply the 
revised standards for the reporting period commencing 1 July 
2009.  However, the new rules generally apply only prospectively to 
transactions that occur after the application date of the standard.  
Their impact will therefore depend on whether the Group will enter 
into any business combinations or other transactions that affect the 
level of ownership held in the controlled entities in the year of initial 
application.  For example, under the new rules:

(cid:129)  all payments (including contingent consideration) to  
  purchase a business are to be recorded at fair value at   

the acquisition date, with contingent payments subsequently  
remeasured at fair value through income

(cid:129)  all transaction cost will be expensed

42  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
(cid:129)  the Group will need to decide whether to continue calculating  
  goodwill based only on the parent’s share of net assets or  
  whether to recognise goodwill also in relation to the non- 
  controlling (minority) interest and

(cid:129)  when control is lost, any continuing ownership interest in the  
  entity will be remeasured to fair value and a gain or loss  

recognised in profi t or loss.

Amendments to IFRS 1 and IAS 27 Cost of an 
Investment in a Subsidiary, Jointly Controlled Entity or 
Associate

In May 2008, the IASB made amendments to IFRS 1 First-time 
Adoption of International Financial Reporting Standards and  IAS 
27 Consolidated and Separate Financial Statements. The new 
rules will apply to fi nancial reporting periods commending on 
or after 1 January 2009.  Amendments to the corresponding 
Australian Accounting Standards are expected to be issued 
shortly.  The Group will apply the revised rules prospectively from 
1 July 2009.

Improvements to the IFRSs

In May 2009, the IASB issued a number of improvements to 
existing International Financial Reporting Standards.  The 
amendments will generally apply to fi nancial reporting periods 
commending on or after 1 January 2009, except for some 
changes to IFRS 5 Non-current Assets Held for Sale and 
Discontinued Operations regarding the sale of the controlling 
interest in a subsidiary which will apply form 1 July 2009.  We 
expect the AASB to make the same changes to Australian 
Accounting Standards shortly.  The Group will apply the revised 
standards from 1 July 2009.  The Group does not expect that 
any adjustments will be necessary as the result of applying the 
revised rules.

www.qrxpharma.com  43

 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

2   FINANCIAL RISK MANAGEMENT

The Group’s activities expose it to a variety of fi nancial risks: market risk (including currency risk and interest rate risk), credit risk and 
liquidity risk.  The Group’s overall risk management programme focuses on the unpredictability of fi nancial markets and seeks to minimise 
potential adverse effects on the fi nancial performance of the Group. The Group uses derivative fi nancial instruments such as foreign 
exchange contracts to hedge certain risk exposures. Derivatives are exclusively used for hedging purposes, not as trading or other 
speculative instruments.  Cash and cash equivalents are invested exclusively with A rated fi nancial institutions, at a minimum, with capital 
preservation being the stated investment objective.  Risk management is carried out under policies approved by the Board of Directors.

The Group and the parent entity hold the following fi nancial instruments:

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

        29,672
           158
              -
              -
           458

35,690
136
922
10,491
           118

        29,583
           135
              -
              -
           119

35,690
136
922
10,491
        -

        30,288

        47,357

        29,837

        47,239 

         2,024
              -

2,024

678
        154

832

        4,169
              -

706
           154

4,169

860

Financial assets

Cash and cash equivalents
Trade and other receivables
Financial assets at fair value through profi t or loss
Held-to-maturity investments
Other fi nancial assets

Financial liabilities

Trade and other payables
Other fi nancial liabilities

(A)  MARKET RISK

(i) Foreign exchange risk

The Group is exposed to foreign exchange risk arising from currency exposure to the US dollar. Foreign exchange risk arises from future 
commercial transactions and recognised assets and liabilities denominated in a currency that is not the entity’s functional currency.

Derivative fi nancial instruments of a net carrying value of $768,214 at 30 June, 2007 have been recognised at a fair value of $nil at 30 
June 2008.

During the fi nancial year ended 30 June 2007, the Group had entered into a series of foreign exchange put option contracts at an 
exchange rate between Australian dollars and US dollars of AUD$1.00 to US$0.8181 to protect against adverse foreign exchange 
movements between AUD and USD.  The option contracts were to cover anticipated expenditure of at least $29 million over 2 years to 
fulfi l research and development expenditure associated with clinical trials to be conducted in the United States of America (US).  The 
Prospectus issued by the Company on 27 April, 2007 assumed an exchange rate between Australian dollars and US dollars of AUD$1.00 
to US$0.78.  During the year the Group converted AUD$20 million to USD at an average rate of US$0.9027, taking advantage of the 
more favourable rates above the option contracts.

In addition, at 30 June 2007 the Group held a series of smart forward exchange contracts which had a fair value as a liability at that date 
of $154,024.

44  QRxPharma  Annual Report 2008

 
These put options contracts cover existing purchase contracts and highly probable forecasted purchases over the ensuing two fi nancial 
years and mature as follows:

Buy US dollars

Sell Australian dollars

Average exchange rate

Maturity

6 – 12 months

1 - 2 years

2008

$’000

2007

$’000

2008

2007

            15,300

          13,200

                  -

          15,300

0.8180

0.8180

0.8180

0.8180

            15,300

28,500

Amounts disclosed above represent currency sold measured at the contracted rate.

The Group’s exposure to foreign currency risk at the reporting date was as follows:

Cash at bank
Term deposits
Trade payables

30 June 2008

30 June 2007

USD

$’000

USD

$’000

333
21,022
116

364
6,669
-

The carrying amounts of the parent entity’s fi nancial assets and liabilities are denominated in Australian dollars except as set out below:

30 June 2008

30 June 2007

USD

$’000

USD

$’000

333
21,022
3,891

364
6,669
-

Cash at bank
Term deposits
Trade payables

Group sensitivity

Based on the fi nancial instruments held at 30 June 2008, had the Australian dollar weakened / strengthened by 10% against the US 
dollar with all other variables held constant, the Group’s post-tax loss for the year would have been $2.5 million lower / $2.0 million higher 
(2007 – $921,000 higher / $753,000 lower), mainly as a result of foreign exchange gains/losses on translation of US dollar denominated 
fi nancial instruments as detailed in the above table.  Profi t is more sensitive to movements in the Australian dollar/US dollar exchange 
rates in 2008 than 2007 because of the increased amount of US dollar denominated cash and cash equivalents.  The Group’s exposure 
to other foreign exchange movements is not material.

Parent entity sensitivity

The parent entity’s post-tax loss for the year would have been $5.7 million lower / $1.7 million higher (2007 - $798,000 lower / $653,000 
higher) had the Australian dollar weakened/strengthened by 10% against the US dollar, mainly as a result of foreign exchange gains/
losses on the translation of US dollar denominated derivatives held for trading.  

www.qrxpharma.com  45

QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

2   FINANCIAL RISK MANAGEMENT (CONTINUED) 

 (ii) Price risk

The Group and the parent entity are not exposed to equity securities price risk or commodity price risk.

(iii) Cash fl ow and fair value interest rate risk

The Group’s main interest rate risk arises from the holding of cash and cash equivalents.  During the year, the Group held signifi cant bank 
accepted commercial bills and term deposit interest-bearing assets exposing the Group’s income and  operating cash fl ows to changes 
in market interest rates

The value of borrowings at 30 June 2008 was $nil (2007 - $nil), thus limiting the Group’s exposure to any cash fl ow risk in relation to 
liabilities.  During the fi nancial year ended 30 June 2007 prior to completion by the Company of its initial public offering, the Group 
converted all outstanding convertible notes, preference shares and warrants to ordinary shares.  The preference shares and convertible 
notes were subject to fi xed interest rate risk of 10% per annum. 

Group sensitivity

As at 30 June 2008, if interest rates had changed by -/+ 125 basis points from the year-end rates with all other variables held constant, 
the post-tax loss for the year would have been $70,100 higher / lower (2007 – change of 125 bps: $22,400 higher / lower), mainly as a 
result of lower/higher interest income from cash and cash equivalents.

Parent entity sensitivity

The parent entity’s main interest rate risk arises from the holding of cash equivalents. As at 30 June 2008, if interest rates had changed 
by -/+ 125 basis points from the year-end rates with all other variables held constant, the post-tax loss would have been $70,100 higher / 
lower (2007 – change of 125 bps: $22,400 higher / lower) as a result of lower / higher interest income from these fi nancial assets.

(B)  CREDIT RISK

Credit risk is managed on a group basis.  Credit risk arises from cash and cash equivalents and deposits with banks and fi nancial 
institutions.  For banks and fi nancial institutions, only independently rated parties with a minimum rating of ‘A’ are acceptable.  At 30 June 
2008, cash equivalents were held with an Aa1 and an A3 fi nancial institution, as rated by Moody’s.

(C)  LIQUIDITY RISK

Prudent liquidity risk management implies maintaining suffi cient cash and marketable securities.

The Group has experienced recurring operating losses and operating cash outfl ows since inception to 30 June 2008. Due to negative 
cash fl ow position the Group has not committed to any credit facilities rather relied upon equity and debt fi nancing through private and 
public equity investors.  On 24 May 2007 and prior to completion by the company of its initial public offering the Series A preference 
shares, convertible notes and warrants have been converted to ordinary shares at a 1.85 conversion rate in accordance with the terms of 
the IPO deed dated 27 April 2007.

The Group and parent entity’s exposure to liquidity risk is restricted to the value of outstanding trade creditors.  Trade payables generally 
have 30 day payment terms, and at 30 June 2008, the Group and parent entities had no overdue liabilities.  The Group is continuously 
monitoring its’ level of expenditure against the Prospectus as funds are expended in accordance with its’ drug development expenditure 
program.    The value of trade creditors at 30 June 2008 for the Group was $1.6 million (2007: $400,000) which is payable within 3 
months of the year end and at 30 June 2008, the entity carried cash and cash equivalents of $29.7 million (2007: $37.5 million).

The value of trade creditors at 30 June 2008 for the parent was $158,000 (2007: $400,000) which is payable within 3 months of the year 
end and at 30 June 2008, the parent entity carried cash and cash equivalents of $29.6 million (2007: $37.5 million).

The Group also holds a Sponsored Research Agreement with the University of Alabama. The Group is committed to paying the University 
of Alabama USD 400,000 per annum, payable quarterly for fi ve years from 25 May 2007. This agreement can be terminated by the Group 
at any time without cause upon 12 months prior written notice to the University of Alabama.

46  QRxPharma  Annual Report 2008

(D)  FAIR VALUE ESTIMATION

The fair value of fi nancial assets and fi nancial liabilities must be estimated for recognition and measurement or for disclosure purposes.

The fair value of fi nancial instruments that are not traded in an active market is determined using valuation techniques.

The carrying value of trade payables are assumed to approximate their fair values due to their short-term nature.

Summarised sensitivity analysis

The following table summarises the sensitivity of the Group’s fi nancial assets and fi nancial liabilities to interest rate risk, foreign exchange 
risk and other price risk.

Carrying
amount
$’000

Foreign exchange risk

Interest rate risk

-10%

+10%

-125bps

+125bps

Profi t
$’000

Equity
$’000

Profi t
$’000

Equity
$’000

Profi t
$’000

Equity
$’000

Profi t
$’000

Equity
$’000

30 June 2008

Financial assets

Cash and cash equivalents

     29,672

     2,465   

Financial liabilities

Trade payables

1,611

(13)

Total increase/decrease

2,452

-

-

-

  (2,017)

11

(2,006)

Carrying
amount
$’000

Foreign exchange risk

-10%

+10%

Profi t
$’000

Equity
$’000

Profi t
$’000

Equity
$’000

30 June 2007

Financial assets

Cash and cash equivalents

     7,033

     934

Financial liabilities

Trade payables

Total increase/decrease

400

(13)

921

-

-

-

  (764)

11

(753)

-

-

-

-

-

-

     (70)

-

     (70)

-

-

-

      70

-

70

Interest rate risk

-125bps

+125bps

Profi t
$’000

Equity
$’000

Profi t
$’000

Equity
$’000

     (22)

-

     (22)

-

-

-

      22

-

22

-

-

-

-

-

-

www.qrxpharma.com  47

QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

3   CRITICAL ACCOUNTING ESTIMATES AND JUDGEMENTS

Estimates and judgements are continually evaluated and are based on historical experience and other factors, including expectations of 
future events that may have a fi nancial impact on the entity and that are believed to be reasonable under the circumstances.

The Group makes estimates and assumptions concerning the future.  The resulting accounting estimates will, by defi nition, seldom equal 
the related actual results.  The estimates and assumptions that have a signifi cant risk of causing a material adjustment to the carrying 
amounts of assets and liabilities within the next fi nancial year are discussed below.

Research and development expenditure

The Group has expensed all internal research and development expenditure incurred during the year as the costs relate to the initial 
expenditure for research and development of biopharmaceutical products and the generation of future economic benefi ts are not 
considered certain. It was considered appropriate to expense the research and development costs as they did not meet the criteria to be 
capitalised under AASB 138.

Fair value of fi nancial assets and liabilities

The Group has entered into a number of Australian dollar (AUD) put option agreements and smart forward exchange contracts to 
purchase US dollar (USD) to manage its exposure to foreign exchange movements. The directors have assessed and measured the 
derivative instruments at their fair value at year end.

Impairment of intangible assets

The Group reviews defi nite life intangibles for impairment whenever events or changes in circumstances indicate that the carrying value 
may not be recoverable. The Group makes estimates and assumptions about the recoverability of intellectual property. Where the 
carrying value of the intellectual property exceeds the recoverable amount, an impairment loss is recognised to record the intellectual 
property at its recoverable amount.

By agreement dated 26 April 2007, between CNS Co. Inc (a company then controlled by Dr John Holaday), QRxPharma Limited, 
QRxPharma Inc and Dr John Holaday, CNS Co. Inc merged with QRxPharma, Inc. Upon the merger CNS Co. Inc ceased to exist and 
QRxPharma Inc became the surviving entity. Under the terms of the merger agreement QRxPharma Inc acquired 100% of the equity of 
CNS Co. Inc with the purchase consideration payable to Dr John Holaday being equivalent to 10% of the post IPO ordinary capital of 
QRxPharma Limited.  As detailed in note 18 (h) this purchase consideration was satisfi ed through the issue of 7,500,000 ordinary shares 
in QRxPharma Limited at the time of the Company’s initial public offering (“IPO”) on 25 May 2007.

Intellectual property of $15.5 million acquired through this merger relates to an exclusive worldwide license from the University of Alabama 
(“UOA”) of certain technology relating to the treatment of central nervous system (CNS) disorders and other related diseases (“Torsin IP”). 
The Torsin IP programme is run through the Caldwell Labs at the UOA and is directed at re engineering existing drug therapies for new 
clinical applications, which include the treatment of dystonia, Parkinson’s disease and other neurological disorders which are a part of the 
Central Nervous System (“CNS”) market. Under the terms of this agreement the Group will use its commercially reasonable best efforts 
to bring a product or process using the Torsin IP to market through a commercially reasonable development programme to meet certain 
milestones. The fi rst milestone is the fi ling of an investigational new drug application for a product within three years. The commercial 
commitments are more fully described in note 22.

At 30 June 2008 this Torsin IP had a carrying value of $14.6 million. Accounting Standard AASB 136 “Impairment of Assets” requires 
the assessment of the Torsin IP for impairment on an annual basis. The ability of an intangible asset such as the Torsin IP to generate 
suffi cient future economic benefi ts to recover its carrying amount is usually subject to greater uncertainty before the asset is capable of 
generating cash fl ows.

Whilst the Company has supported the enhancement of the Torsin IP to date, the board’s decision to focus on the Company’s pain relief 
assets implies that, in its current development stage, the Torsin IP could not generate cash fl ow other than from the out-licence or sale of 
the asset. As no contracts have at 30 June 2008 been negotiated for either the out-licence or sale of the Torsin IP, the Company has fully 
impaired the carrying value of the asset at 30 June 2008 being  $14.6 million pursuant to the requirements of AASB 136. 

48  QRxPharma  Annual Report 2008

It should be noted in fully impairing the carrying value of this asset at 30 June 2008 does not mean the abandonment of the programme 
with the UOA as it is believed that the asset still has long term value and remains part of the Company’s preclinical and clinical pipeline of 
pharmaceuticals. 

Black- Scholes option pricing model

During the year, the Group booked $3.3 million of share-based payments as determined through the application of the Black- Scholes 
option pricing model.  The Black-Scholes model is dependent on a number of variables and estimates fully described in note 28.

4   SEGMENT INFORMATION

The Group’s operations during the year were predominantly in Australia.  The Group operates in only one market segment, that of the 
research and development of biopharmaceutical products for commercial sale.

5   REVENUE

From continuing operations

Interest

6   OTHER INCOME

Management fees
Gain on conversion of fi nancial instruments

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

2,009  

304  

2,009

304

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

             -
             -

             -
         4,951

           515
              -

             -
         4,951

-

         4,951

           515

         4,951

On 24 May 2007 the Series B convertible notes and Series A preferred shares were converted into ordinary shares (refer note 18 (e)).

www.qrxpharma.com  49

 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

7 EXPENSES

Loss before income tax includes the following specifi c expenses:

Depreciation and Amortisation 

Plant and equipment 
Amortisation of intangible assets

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

20
           802

822

2,618

-
-

-

-

2,907
38
2,353

5,298

11
            72

16
              -

11
             -

83

272

371
1,126

1,497

359

457
8
225

690

16

11

2,648

272

-
-

-

-

1,136
38
1,664

2,838

371
1,126

1,497

359

457
8
225

690

12,708
        14,628

2,376
              -

13,970
              -

2,376
              -

27,336

2,376

13,970

2,376

-

73

-

-

17,117

27

-

-

Net foreign exchange loss

Finance costs 

Interest payable on convertible notes
Interest payable on preference shares

Fair value losses on derivative fi nancial instrument

Employee benefi t expense  

Employee benefi t expense 
Defi ned contribution superannuation expense
Share option expense

Research and development

Research and development expensed
Impairment of intangible asset

Impairment losses – fi nancial assets

    Investment in subsidiary 

Rental expenses relating to operating leases

    Minimum lease payments

50  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
8   INCOME TAX BENEFIT 

(A)  INCOME TAX BENEFIT

Current tax
Deferred tax expense

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

     -
(125)

(125)

       -
(348)

(348)

           -
(125)

(125)

2007

$’000

          -
(348)

(348)

The deferred tax asset relates to a Research and Development tax rebate payment received during the year under Section 73 B of the 
Income Tax Assessment Act 1936.

(B)  NUMERICAL RECONCILIATION OF INCOME 
TAX EXPENSE TO PRIMA FACIE TAX PAYABLE

Loss from continuing operations before income tax expense

Tax at the Australian tax rate of 30% (2007 – 30%)

Tax effect of amounts which are not deductible in calculating 
taxable income:

Amortisation of intangibles
Impairment of intangible asset
Impairment of fi nancial asset
Research & development expenditure
Share-based payments
Interest on preference shares

Consolidated

Parent

2008

$’000

(36,727)

(11,018)

2007

$’000

2008

$’000

2007

$’000

(753)

(226)

(37,113)

(11,134)

(681)

(205)

241
4,388
-
 -      
779
              -

(5,610)

21
-
-
574         
  67
        (1,103)

(667)

-
-
5,135
-
779
              -

(5,220)

-
-
-
574
67        
(1,103)

(667)

Previously unrecognised losses recouped
Benefi t of tax losses not recognised

Income tax expense

           (125)
         5,610

         (125)

(348)
           667

            (125)
         5,220

   (348)
          667

(348)

            (125)

   (348)

(C)  TAX LOSSES

Unused tax losses for which no deferred tax asset has been 
recognised

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

        27,513

       8,813

        26,213

        8,813

Potential tax benefi t @ 30%

         8,254

         2,644

         7,864

         2,644

No deferred tax asset has been recognised for the tax losses generated from operations in both Australia and the USA, as the benefi t for 
tax losses will only be obtained if:

(i)  the Group derives future assessable income of a nature and of an amount suffi cient to enable the benefi t from the deductions for the 
losses to be realised, or

(ii)  the Group continues to comply with the conditions for deductibility imposed by tax legislation, and

(iii)  no changes in tax legislation adversely affect the Group in realising the benefi t from the deduction for the losses.

www.qrxpharma.com  51

 
 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

8   INCOME TAX BENEFIT  (CONTINUED) 

(D)  TAX CONSOLIDATION LEGISLATION

QRxPharma Limited and its wholly owned Australian controlled entities have implemented the tax consolidation legislation as of 7 
December 2002.   The accounting policy in relation to this legislation is set out in note 1(g).

9   CURRENT ASSETS – CASH AND CASH EQUIVALENTS

Cash at bank
Term deposits
Commercial bills

(A)  CASH AT BANK

Consolidated

Parent

2008

$’000

654
21,839
7,179

29,672

2007

$’000

2,339
6,669
        26,682

35,690

2008

$’000

2007

$’000

565
21,839
7,179

29,583

2,339
         6,669
        26,682

35,690

These bear an interest rate of 7.3% (2007: 5.98%) for the AUD accounts and 1.0% (2007: 3%) for the USD accounts.

(B)  TERM DEPOSITS

These are USD deposits and bear an average fi xed interest rate of 2.3% (2007: 5.1%). These deposits have a maturity of less than 3 
months.  

(C)  COMMERCIAL BILLS

These commercial bills are bearing an average interest rate of 7.40% (2007: 6.30%) and have a maturity of less then 3 months.  

Bank accepted commercial bills and term deposits with a maturity greater than 3 months have been classifi ed as held-to-maturity 

investments (refer note 12).

10  CURRENT ASSETS – TRADE AND OTHER RECEIVABLES

Interest receivable
Other receivables

Consolidated

Parent

2008

$’000

105
            53

158

2007

$’000

2008

$’000

2007

$’000

57
79

136

105
            30

           135  

57
79

136

Information about the Group’s and the parent’s exposure to foreign currency and interest rate risk in relation to other receivables is 
provided in note 2.

Due to the short term nature of these receivables, their carrying amount is assumed to approximate their fair value.

52  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
11  OTHER FINANCIAL ASSETS AND LIABILITIES AT FAIR VALUE THROUGH PROFIT OR LOSS

Current assets

Derivative fi nancial instrument 

Total current assets

Non-current assets

Derivative fi nancial instrument

Total non current assets

Total assets

Current liabilities

Derivative fi nancial instrument

Total liabilities

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

-

-

-

-

-

-

-

374  

374

-

           -

548

548

922

154

154

-

-

-

-

-

374

374

548

548

922

154

154

INSTRUMENTS USED BY THE GROUP

Derivative fi nancial instruments of a net carrying value of $768,214 at 30 June, 2007 have been fair valued to $nil at 30 June 2008.

During the fi nancial year ended 30 June 2007, the Group had entered into a series of foreign exchange put option contracts at an 
exchange rate between Australian dollars and US dollars of AUD 1.00 to USD 0.8181 to protect against adverse foreign exchange 
movements between AUD and USD.  The options contracts were to cover anticipated expenditure of at least $29 million over 2 years 
to fulfi l research and development expenditure associated with clinical trials to be conducted in the United States of America.  The 
Prospectus issued by the Company on 27 April, 2007 assumed an exchange rate between Australian dollars and US dollars of AUD 1.00 
to USD 0.78.  During the year the Group converted AUD 20 million to USD at an average rate of US$0.9027, taking advantage of the more 
favourable rates above the option contracts.

In addition, at 30 June 2007 the Group held a series of smart forward exchange contracts which were fair valued as a liability at that date 
at $154,024.

These put options contracts are covering existing purchase contracts and highly probable forecasted purchases over the ensuing two 
fi nancial years and mature as follows:

Buy US dollars

Sell Australian dollars

Average exchange rate

Maturity

6 – 12 months

1 - 2 years

2008

$’000

2007

$’000

2008

2007

            15,300

          13,200

                  -

          15,300

            15,300

28,500

0.8180

0.8180

0.8180

0.8180

Amounts disclosed above represent currency sold measured at the contracted rate.

www.qrxpharma.com  53

 
 
 
 
 
   
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

12  CURRENT ASSETS – HELD-TO-MATURITY INVESTMENTS

Commercial bill
Security deposit

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

-
-

-

         9,691
           800

        10,491

-
-

         9,691
           800

           -

        10,491

The bank accepted commercial bill of $9.7 million, bearing an interest rate of 6.47% was due to mature on 19 December 2007, but was 
matured early on 14 November 2007.  The proceeds were converted into US dollars and reinvested in term deposits having maturities of 
less than 3 months from original investment date.  The security deposit of $0.8 million bearing a fi xed interest rate of 6.2% matured on 18 
May 2008.  The proceeds were reinvested in commercial bills having a maturity of less than 3 months from the original investment date.  
Accordingly these amounts have been reclassifi ed and disclosed as cash and cash equivalents in accordance with AASB 107 “Cash 
Flow Statements”.

13  CURRENT ASSETS – OTHER CURRENT ASSETS

Prepayments

458  

118

119

       -

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

14  NON CURRENT ASSETS – OTHER FINANCIAL ASSETS

Investment in subsidiaries (note 25)
Less provision for write down to recoverable amount

These fi nancial assets are carried at cost.

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

-
-

-

        -
-

       -

20,223
       (17,618)

16,121
          (501)

         2,605

        15,620

Due to the impairment loss on the Torsin IP asset recognised in the books of the subsidiary, a provision for diminution in value against the 
investment in the books of the parent entity has been recognised. Refer to note 3.

54  QRxPharma  Annual Report 2008

 
 
 
15  NON–CURRENT ASSETS – PROPERTY, PLANT AND EQUIPMENT 

Consolidated

Plant & Equipment
$’000

Parent

Plant & Equipment
$’000

At 1 July 2006

Cost
Accumulated depreciation

Net book amount

Year ended 30 June 2007

Opening net book amount
Additions
Depreciation charge

Closing net book amount

At 30 June 2007

Cost
Accumulated depreciation

Net book amount

Year ended 30 June 2008

Opening net book amount
Additions
Depreciation charge

Closing net book amount

At 30 June 2008

Cost
Accumulated depreciation

Net book amount

109
 (91)

18

18
18
 (11)

25

127
 (102)

25

25
68
(20)

73

195
(122)

73

109
(91)

18

18
18
 (11)

25

127
 (102)

25

25
28
(16)

37

155
(118)

37

www.qrxpharma.com  55

 
 
 
 
 
 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

16  NON–CURRENT ASSETS – INTANGIBLE ASSETS

Consolidated

Year ended 30 June 2007

Opening net book amount
Acquisition of intellectual property
Amortisation charge

Closing net book amount

At 30 June 2007

Cost
Accumulated amortisation and impairment

Net book amount

Consolidated

Year ended 30 June 2008

Opening net book amount
Impairment of intellectual property*
Amortisation charge

Closing net book amount

At 30 June 2008

Cost
Accumulated amortisation and impairment

Net book amount

Patents,
trademarks and other 
rights
$’000

Other intangible assets
$’000

Total
$’000

-
15,502
(72)

15,430

15,502
(72)

15,430

-
-

-
15,502
(72)

           -

        15,430

889
(889)

-

16,391
(961)

15,430

Patents,
trademarks and other 
rights
$’000

Other intangible assets
$’000

Total
$’000

15,430
(14,628)
(802)

-

15,502
(15,502)

-

-
-
-

           -

889
(889)

-

15,430
(14,628)
(802)

        -

16,391
(16,391)

-

*The carrying amount of the Torsin IP asset has been reduced to its recoverable amount of $nil through recognition of an impairment loss 
against the asset.  This loss has been disclosed as a separate line item in the income statement.  Refer to note 3.

56  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
16  NON–CURRENT ASSETS – INTANGIBLE ASSETS (CONTINUED) 

Parent

At 1 July 2006

Cost
Accumulated amortisation and impairment

Net book amount

Year ended 30 June 2007

Opening net book amount

Closing net book amount

At 30 June 2007

Cost
Accumulated amortisation and impairment

Net book amount

Year ended 30 June 2008

Opening net book amount

Closing net book amount

At 30 June 2008

Cost
Accumulated amortisation and impairment

Net book amount

Patents,
trademarks and other 
rights
$’000

Other intangible assets
$’000

Total
$’000

-
-

-

-

-

-
-

-

-

-

-
-

-

414
(414)

           -

-

-

414
(414)

           -

-

-

414
(414)

           -

414
(414)

-

-

-

414
(414)

-

-

-

414
(414)

-

17  CURRENT LIABILITIES – TRADE AND OTHER PAYABLES

Trade payables
Amounts due to subsidiaries
Accrued employee benefi ts
Other payables

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

1,611
-
92
321

2,024

400
-
272
6

678

158
3,802
32
177

4,169

400
28
272
6

706

Accrued employee benefi ts include accruals for annual leave.  The entire obligation is presented as current, since the Group does not 
have an unconditional right to defer settlement.  It is expected that employees will use the full amount of accrued leave within the next 12 
months.

www.qrxpharma.com  57

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

18  CONTRIBUTED EQUITY 

(A)  SHARE CAPITAL

Ordinary shares  –  fully paid

Parent

Parent

2008
Shares

2007
Shares

2008
$’000

2007
$’000

75,000,000

75,000,000

79,694

79,932

(B)  MOVEMENTS IN ORDINARY SHARE CAPITAL:

Details

Notes

Number of 
shares

Issue price

$’000

Date

1 July 2006
11 August 2006
12 March 2007
19 April 2007
25 April 2007
25 April 2007
25 April 2007
24 May 2007
24 May 2007
24 May 2007
24 May 2007
24 May 2007
25 May 2007
25 May 2007
25 May 2007

Opening balance
Exercise of options
Exercise of options
Exercise of options
Exercise of options
Exercise of options   net
Issue of shares
Conversion of Preferred Shares Series A 
Conversion of Convertible Note Series A
Conversion of Convertible Note Series B
Conversion of Convertible Note Series B Warrants
Issue of shares in settlement of IP deed
Compression of shares prior to IPO
Share issue to acquire subsidiary
Share issue from IPO
Less: Transaction costs arising on IPO
Less: Transaction costs arising on other capital raising

(d)
(d)
(d)
(d)
(d)
(d)
(e)
(e)
(e)
(e)
(f)
(g)
(h)
(i)

30 June 2007 Balance

Less: Transaction costs arising on share issues

      30 June 2008 Balance

(C)  ORDINARY SHARES

$0.15
$0.15
$0.15
$0.15

$0.54
$0.54
$0.27
$0.27
$1.00

$2.00
$2.00

7,588,721
9,120
60,000
654,192
80,000
653,640
509,325
18,960,911
5,674,837
5,550,000
5,550,000
1,912,500
(4,703,246)
7,500,000
25,000,000

75,000,000

  75,000,000

670
1
9
98
12
-
-
9,898
3,068
1,500
1,500
1,913
-
15,000
50,000
(3,699)
(38)

79,932

       (238)

      79,694

Each ordinary shareholder maintains, when present in person or by proxy or by attorney at any general meeting of the company, the right 
to cast one vote for each ordinary share held.

Ordinary shares entitle the holder to participate in dividends and the proceeds on winding up of the company in proportion to the number 
of and amounts paid on the shares held.

(D)  OPTIONS

Information relating to the QRxPharma Limited Employee Share Option Plan, including details of options issued, exercised and lapsed 
during the fi nancial year and options outstanding at the end of the fi nancial year are set out in note 28.

On 25 April 2007 cashless options were exercised resulting in the issue of 653,640 shares.

Certain options carried anti dilution provisions which resulted in an uplift of 509,325 options which were exercised at the same time.

58  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
These shares were issued to directors and key management personnel of the Group during the year ended 30 June 2007.

(E)  CONVERSION OF SERIES A PREFERENCE SHARES, CONVERTIBLE NOTES AND WARRANTS

On 24 May 2007 and prior to completion by the company of its IPO the Series A preference shares, convertible notes and warrants were 
converted to ordinary shares at a 1.85 conversion rate in accordance with the terms of the IPO deed dated 27 April 2007.

(F)  ISSUE OF SHARES IN SETTLEMENT OF IP DEED

On 24 May 2007 the Company issued 1,912,500 ordinary shares to Uniquest Pty Limited at $1.00 per share to compensate Uniquest Pty 
Limited for early settlement of an intellectual property subscription deed.

(G)  SHARE CONSOLIDATION

On 25 May 2007 and also prior to the IPO, the company completed a consolidation of ordinary shares which reduced the number of 
shares on a issue by factor per share of 0.90036.

(H)  SHARE ISSUE TO ACQUIRE SUBSIDIARY

The Group acquired 100% of the equity of CNS Co, Inc. on 26 April 2007 for consideration equivalent to 10% of the post IPO ordinary 
capital of the Company.

(I)   SHARE ISSUE FROM IPO

On 25 May 2007 the company listed on the Australian Securities Exchange (ASX) following the completion of a fully underwritten IPO with 
a subscription of 25,000,000 ordinary shares at an issue price of $2.00 per share.

(J)  VOLUNTARY ESCROWS

Certain directors, consultants and pre IPO investors have voluntarily escrowed their shareholdings in the Company. Collectively these 
escrows extend to 34,229,407 ordinary shares through to 25 May 2009.  At 25 May 2008, voluntary escrows on 10,075,929 ordinary 
shares expired.

(K)  CAPITAL RISK MANAGEMENT

The Group’s and the parent entity’s objectives when managing capital are to safeguard their ability to continue as a going concern, so 
they can continue to provide returns for shareholders and benefi ts for other stakeholders and to maintain an optimal capital structure to 
reduce the cost of capital.

In order to maintain or adjust the capital structure, the Group may, return capital to shareholders; issue new shares or sell assets.

www.qrxpharma.com  59

QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

19  RESERVES AND ACCUMULATED LOSSES

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

3,899
          (315)

387
              -

3,899
              -

387
              -

         3,584  

387  

3,899

387

(A)  RESERVES

Share-based payments reserve
Foreign currency translation reserve

MOVEMENTS:

Share-based payments reserve

Balance 1 July
Option expense
Options issued to employees of subsidiaries
Options issued under anti dilution provisions

Balance 30 June

3,899  

387  

Foreign currency translation reserve
    Balance 1 July
    Currency translation differences arising during the year

Balance 30 June

-
          (315)

          (315)

-
-

-

  387
3,512
-
-

162
149
-
76

387
2,691
821
-

3,899

-
-

-

162
149
-
76

387

-
-

-

(18,339)
(36,602)

(54,941)

(17,934)
(405)

(18,339)

(18,295)
(36,988)

(17,962)
(333)

(55,283)

(18,295)

(B)  ACCUMULATED LOSSES

Movements in accumulated losses were as follows:

Opening accumulated losses
Loss for the year

Balance 30 June

(C)  NATURE AND PURPOSE OF RESERVES

(i) Share-based payments reserve

The share-based payment reserve is used to recognise:

  (cid:129)  the fair value of options issued to employees but not exercised

  (cid:129)  the fair value of shares issued to employees

  (cid:129)  in the parent entity – the fair value of shares and options issued to employees of subsidiaries

(ii)  Foreign currency translation reserve

Exchange differences arising on translation of the foreign controlled entity are taken to the foreign currency translation reserve, as 
described in note 1(e).  The reserve is recognised in profi t and loss when the net investment is disposed.

60  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
20  KEY MANAGEMENT PERSONNEL DISCLOSURES

(A)  DIRECTORS

The following persons were directors of QRxPharma Limited during the fi nancial year:

(i)   Chairman – non executive

Peter C Farrell 

(ii)  Executive director

John W Holaday, Managing Director and Chief Executive Offi cer 

(iii)  Non executive directors

Michael A Quinn

R Peter Campbell 

Gary W Pace, Consultant

(B)  OTHER KEY MANAGEMENT PERSONNEL

The following persons also had authority and responsibility for planning, directing and controlling the activities of the Group, directly or 
indirectly, during the fi nancial year:

Name

Position

Douglas A Saltel 

Chief Operating Offi cer

(resigned 7 March 2008)

Warren C Stern

Executive Vice President, Drug Development 

Chris J Campbell

Chief Financial Offi cer and Company Secretary

Joseph J Berry

Vice President Operations

(appointed 12 November 2007)

Philip J Magistro

Vice President, Commercial Operations

(appointed 26 November 2007)

Patricia T Richards

Senior Vice President, Clinical Research

(appointed 18 February 2008)

All of the above persons were also key management persons during the year ended 30 June 2007, except for Patricia Richards, 
Philip Magistro and Joseph Berry.

(C)  KEY MANAGEMENT PERSONNEL COMPENSATION

Short term employee benefi ts

Post employment benefi ts

Long term benefi ts

Share-based payments

Consolidated

Parent

2008

$

 2,123,952

28,102

-

2007

$

445,725

 8,327

-

2008

$

2007

$

968,263

445,725

28,102

 8,327

-

-

2,361,213

171,207

1,674,644

171,207

4,513,267

625,259

2,671,009

625,259

The company has taken advantage of the relief provided by Corporations Regulation 2M.6.04 and has transferred the detailed remuneration 
disclosures to the directors’ report.  The relevant information can be found in sections A-C of the remuneration report on pages 14 to 19. 

www.qrxpharma.com  61

 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

20  KEY MANAGEMENT PERSONNEL DISCLOSURES (CONTINUED)

(D)  EQUITY INSTRUMENT DISCLOSURES RELATING TO KEY MANAGEMENT PERSONNEL

(i) Options provided as remuneration and shares issued on exercise of such options

Details of options provided as remuneration and shares issued on the exercise of such options, together with terms and conditions of the 
options, can be found in section D of the remuneration report on pages 19 - 21.

(ii)  Option holdings

The numbers of options over ordinary shares in the company held during the fi nancial year by each director of QRxPharma Limited and 
other key management personnel of the Group, including their personally related parties, are set out below.

2008

Name

Balance at 
start of the 
year

Granted as 
compensation

Exercised

Forfeited

Balance at 
end of the 
year

Vested and 
exercisable

Unvested

Directors of QRxPharma Limited

Peter C Farrell
John W Holaday
Gary W Pace
Michael A Quinn
R Peter Campbell

604,089
805,452
402,726
402,726
241,635

Other key management personnel  of the Group

Warren C Stern
Douglas A Saltel 
(resigned 7 March 2008)
Chris J Campbell
Patricia T Richards 
(appointed 18 February 2008)
Philip J Magistro 
(appointed 26 November 2007)
Joseph J Berry 
(appointed 12 November 2007)

805,452
805,452

402,726
-

-

-

-
-
-
-
-

-
-

-
500,000

200,000

150,000

-
-
-
-
-

- 
-

-
-

-

-

-
-
-
-
-

604,089
805,452
402,726
402,726
241,635

201,363
268,484
134,242
134,242
80,545

402,927
536,968
268,484
268,484
161,090

 -
805,452

805,452
-

268,484
-

536,968
-

-
-

-

-

402,726
500,000

200,000

150,000

134,242
-

268,484
500,000

-

-

200,000

150,000

62  QRxPharma  Annual Report 2008

 
 
(ii)  Option holdings (continued)

2007

Name

Balance at 
start of the 
year

Granted as 
compensation

Exercised

Forfeited

Balance at 
end of the 
year

Vested and 
exercisable

Unvested

Directors of QRxPharma Limited

Peter C Farrell
John W Holaday
Gary W Pace
Michael A Quinn
R Peter Campbell
David Stack 
(resigned 27 April 2007)

-
-
207,096
-
-
447,096

Other key management personnel  of the Group

Warren C Stern
Douglas A Saltel 
Chris J Campbell
Felix de la Iglesia 
(resigned 25 May 2007)
B Nicholas Harvey 
(resigned 1 March 2007)

-
-
-
-

131,788

-

604,089
805,452
402,726
402,726
241,635
-

805,452
805,452
402,726
50,000

-
-
(207,096)
-
- 
(447,096)

- 
-
-
-

-

-
-
-
-
-
-

-
-
-
-

604,089
805,452
402,726
402,726
241,635
-

805,452
805,452
402,726
50,000

(131,788)

-

-
-
-
-
-
-

- 
-
-
-

-

604,089
805,452
402,726
402,726
241,635
-

805,452
805,452
402,726
50,000

-

The additional shares issued to the directors on 25 April 2007 under the anti dilution provision (note 18(d)) were:

Name

Shares issued

Directors of QRxPharma Limited

Gary W Pace
David Stack

71,689
154,768

Other key management personnel  of the Group

Felix de la Iglesia
B Nicholas Harvey

88,996
45,620

www.qrxpharma.com  63

 
 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

20  KEY MANAGEMENT PERSONNEL DISCLOSURES (CONTINUED)

(iii)  Share holdings

The numbers of shares in the company held during the fi nancial year by each director of QRxPharma Limited and other key management 
personnel of the Group, including their personally related parties, are set out below.  There were no shares granted during the reporting 
period as compensation.

2008

Name

Directors of QRxPharma Limited

Ordinary shares

Peter C Farrell 
John W Holaday 
Gary W Pace
Michael A Quinn
R Peter Campbell 

Other key management personnel  of the Group

Ordinary shares

Warren C Stern
Douglas A Saltel (resigned 7 March 2008)
Chris J Campbell
Patricia T Richards (appointed 18 February 2008)
Philip J Magistro (appointed 26 November 2007)
Joseph J Berry (appointed 12 November 2007)

2007

Name

Directors of QRxPharma Limited

Ordinary shares

Peter C Farrell (appointed 27 April 2007)
John W Holaday (appointed 27 April 2007)
Gary W Pace
Michael A Quinn
R Peter Campbell (appointed 27 April 2007)
David Stack (resigned 27 April 2007)
Michael S Hirshorn (resigned 27 April 2007)
George Savage (resigned 27 April 2007)
David A Henderson (resigned 27 April 2007)

Other key management personnel  of the Group

Ordinary shares

Warren C Stern
Douglas A Saltel
Chris J Campbell
Felix de la Iglesia (resigned 25 May 2007)
B Nicholas Harvey (resigned 1 March 2007)

64  QRxPharma  Annual Report 2008

Balance at start 
of the year

Received during 
the year on the 
exercise of options 

Other changes
during the year

Balance at the end
of the year

1,145,540
7,505,000
3,190,083
10,593,090
50,000

- 
-
-
-
-
-

-
-
-
-
-

- 
-
-
-
-
-

135,000
38,000
40,000
(1,121,341)
35,000

1,280,540
7,543,000
3,230,083
9,471,749
85,000

- 
-
-
-
-
-

- 
-
-
-
-
-

Balance at start 
of the year

Received during 
the year on the 
exercise of options 

Other changes
during the year

Balance at the end
of the year

-
- 
1,573,511
500,000
-
-
-
-
-

-
-
-
607,096
175,000

-
-
207,096
-
-
447,096
-
-
-

- 
-
-
-
131,788

1,145,540
7,505,000
1,409,476
10,093,090
50,000
94,799
-
-
-

- 
-
-
773,270
(157,040)

1,145,540
7,505,000
3,190,083
10,593,090
50,000
541,895
-
-
-

- 
-
-
1,380,366
149,748

(E)  OTHER TRANSACTIONS WITH KEY MANAGEMENT PERSONNEL

During the year, the company directly engaged and contracted the services of certain key management personnel to perform consulting 
services for the Group. The total amount paid to key management personnel for contracted services rendered during the year amounted 
to $239,443 (2007: $321,716). Prior to a number of consultants becoming key management personnel of the Group, they were paid 
$67,800 for consulting services.

During the year ended 30 June 2007, Innovation Capital Associates Pty Limited, of which Michael Quinn is a director and shareholder, 
provided administration and other services and facility support to the Company on normal commercial terms amounting to $97,930. 

21  REMUNERATION OF AUDITORS

(A)  AUDIT SERVICES

PricewaterhouseCoopers Australian fi rm

Audit and review of fi nancial reports and other audit work 
under the Corporations Act 2001

Total remuneration for audit services

(B)  NON-AUDIT SERVICES

PricewaterhouseCoopers Australian fi rm

Audit related services
Taxation services

Total remuneration for audit related services

Consolidated

Parent

2008
$

2007
$

2008
$

2007
$

86,000

86,000

97,200

97,200

86,000

86,000

97,200

97,200

-
99,270

99,270

185,270

145,000
80,300

225,300

322,500

-
99,270

99,270

185,270

145,000
80,300

225,300

322,500

22  CONTINGENCIES 

As detailed in note 18(h) the Group acquired on 26 April 2007 a 100% interest in CNS Co, Inc. As also detailed in note 16 the Group 
through this acquisition now holds a license agreement with University of Alabama (USA). Under the terms of this license agreement the 
Group is obligated to meet certain milestone payments as advances against future royalties from the Torsin programme as follows:

(i)   USD 750,000 on commencement by the Group of Phase II clinical trial for any Torsin IP product;

(ii)  USD 1,500,000 on commencement by the Group of Phase III clinical trial for any Torsin IP product;

(iii)  USD 2,000,000 on the date of receipt by the Group of fi rst market approval for each Torsin IP product.

The agreement may be terminated by the Group at any time on 6 months notice to the University of Alabama and upon payment of all 
amounts due to University of Alabama to the effective termination date. The agreement will expire on the last expire date of the patents 
licensed under the agreement.

23  COMMITMENTS 

(A)  UNIVERSITY OF ALABAMA.                                                                                   

  The Group also holds a Sponsored Research Agreement with the University of Alabama. The Group is committed to paying the  
  University of Alabama USD 400,000 per annum, payable quarterly for fi ve years from 25 May 2007. This agreement can be  

terminated by the Group at any time without cause upon 12 months prior written notice to the University of Alabama.

www.qrxpharma.com  65

 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

23  COMMITMENTS (CONTINUED)

(B)  UNIVERSITY OF QUEENSLAND

    On 10 January 2008, the Company entered into a Collaborative Reserach Agreement with the University of Queensland for the  

  conduct of the Australian Research Council linkage project grant; “Pre-clinical evaluation of snake venom proteins with therapeutic   
  potential”.  Under the terms of this grant, the Company is contracted to pay a total of $209,000 to the University over the next two    
  years.

(C)  OPERATING LEASES

  The Group leases offi ce premises in Sydney, Australia and New Jersey, USA.  The leases have varying terms, escalation clauses and  

renewal rights.  

Commitments for minimum lease payments in 
relation to non-cancellable operating leases are
payable as follows:

Within one year
Later than one year but not later than fi ve years
Later than fi ve years

24 RELATED PARTY TRANSACTIONS

(A)  SUBSIDIARIES

Interests in subsidiaries are set out in note 25.

(B)  KEY MANAGEMENT PERSONNEL

Consolidated

Parent

2008

$’000

2007

$’000

2008

$’000

2007

$’000

100
171
-

271

-
-
-

-

19
21
-

40

-
-
-

-

  Disclosures relating to key management personnel are set out in note 20.

(C)  OUTSTANDING BALANCES 

  The following balances are outstanding at the reporting date in relation to transactions with related parties:

Current payables 
Subsidiaries
Balances in relation to related parties

Consolidated

Parent

2008

$

2007

$

2008

$

2007

$

-
-

-
45,199

3,802,332
-

27,700
45,199

66  QRxPharma  Annual Report 2008

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(D)   TRANSACTIONS WITH RELATED PARTIES 

The following transactions occurred with related parties:

Consolidated

Parent

2008

$

2007

$

2008

$

2007

$

Other income

Management services to subsidiary

Expenses

Research and development service fees and costs from subsidiary

-

-

-

-

515,205

13,107,627

-

-

25  SUBSIDIARIES

The consolidated fi nancial statements incorporate the assets, liabilities and results of the following subsidiaries in accordance with the 
accounting policy described in note 1(c):

Name of entity

Country of incorporation

Class of shares

The Lynx Project Pty Limited
Haempatch Pty Limited
QRxPharma, Inc.

Australia
Australia
USA

   Ordinary 
Ordinary /Preference
Ordinary

Equity holding

2008
%

100
100
100

2007
%

100
100
100

26  RECONCILIATION OF PROFIT AFTER INCOME TAX TO NET CASH OUTFLOW 
    FROM OPERATING ACTIVITIES

Loss for the year
Depreciation and amortisation
Impairment of intangible asset
Impairment of fi nancial asset
Non cash employee benefi ts expense – share-based payments
Net exchange differences on cash and cash equivalents
Interest on held-to-maturity investments
Change in operating assets and liabilities

(Increase)/decrease in other receivables and prepayments
Increase/(decrease) in trade creditors and accruals
Increase/(decrease) in other operating liabilities

Consolidated

Parent

2008

$’000

(36,602)
822
       14,628
            -
3,257
2,353
(355)

2007

$’000

         (405)
            83
-
-
           225
           272
-

2008

$’000

(36,988)
16
             -
       16,267
3,305
2,648
(355)

2007

$’000

         (333)
           11
-
-
          225
          272
-

511
1,239
-

     (254)
            78
        (2,534)

804
3,309
-

    (135)
           78
       (2,527)

Net cash outfl ow from operating activities

(14,147)

        (2,535)

(10,994)

(2,409)

www.qrxpharma.com  67

 
 
 
 
 
 
 
 
 
 
     
 
 
 
 
 
 
     
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

27  LOSS PER SHARE

Consolidated

2008
Cents

2007
Cents

(A)  BASIC LOSS PER SHARE

Loss from continuing operations attributable to the ordinary equity holders of the company

(48.8)

(2.8)

(B)  DILUTED LOSS PER SHARE

Loss from continuing operations attributable to the ordinary equity holders of the company

(48.8)

(2.8)

(C) RECONCILIATIONS OF EARNINGS USED IN CALCULATING     
     EARNINGS PER SHARE

Basic loss per share

Loss attributable to the ordinary equity holders of the company used in calculating basic 
earnings per share

Diluted loss per share

Consolidated

2008
$’000

(36,602)

2007
$’000

(405)

Loss attributable to the ordinary equity holders of the company used in calculating diluted 
earnings per share

(36,602)

(405)

(D)  WEIGHTED AVERAGE NUMBER OF SHARES USED AS THE 
      DENOMINATOR

Weighted average number of ordinary shares used as the denominator in calculating basic 
loss per share

Weighted average number of ordinary shares and potential ordinary shares used as the 
denominator in calculating diluted loss per share

Consolidated

2008
Number

2007
Number

75,000,000

14,606,882

75,000,000

14,606,882

(E)  INFORMATION CONCERNING THE CLASSIFICATION OF SECURITIES

(i)   Options

Options are considered to be potential ordinary shares. The options are not included in the calculation of diluted earnings per share 
because they are anti dilutive. These options could potentially dilute basic earnings per share in the future. Details relating to the options 
are set out in note 28.

(ii)  Cumulative redeemable preference shares

The cumulative redeemable preference shares are not ordinary shares and have not been included in the determination of basic and 
diluted earnings per share.  These shares are classifi ed as liabilities (refer to note 18).

68  QRxPharma  Annual Report 2008

28  SHARE-BASED PAYMENTS

(A)  QRXPHARMA EMPLOYEE SHARE OPTION PLAN (ESOP)

The QRxPharma Limited Employee Share Option Plan (Limited ESOP) was approved by shareholders at the extraordinary general meet-
ing of members held on 24th April 2007. 

Under the Limited ESOP shares may be issued by the company to eligible employees at an exercise price as determined by the remu-
neration committee, being not less than the share price on the grant date of the options.  Any person who is employed by, or is a director, 
offi cer, executive or consultant of the Company or any related body corporate of the Company and whom the remuneration committee 
determines is eligible to participate in the option plan are eligible to participate in the plan. Employees may elect not to participate in the 
scheme.

The total number of shares that shall be reserved for issuance under the option plan shall not exceed ten percent (10%) of the Diluted Or-
dinary Share Capital in the Company as at the date of issue of the relevant options under the option plan, subject to changes in capitali-
zation as provided in clause 16.3 of the option plan. The approval of the Company’s shareholders must be obtained for any amendment 
to the option plan in relation to:

(a) increasing the maximum aggregate number of shares that may be issued under the option plan;

(b) any change in the class of employees eligible to receive options under the option plan;

(c) any change in the shares reserved for issuance under the option plan; and

(d) substitution of another entity in place of the Company as the issuer of shares under the option plan.

Options will lapse if they are not exercised before the expiration date or if the option holder leaves the employment of the Group.  The 
Board reserves discretion to waiver the latter provisions.

Options granted under the plan carry no dividend or voting rights. The vesting period for each option is 3 years, or as varied by the Board, 
one third vesting 12 months from the date of grant and the balance vesting equally each year over the remaining two year period. When 
exercisable, each option is convertible into one ordinary share and entitles the holder to the same ordinary share rights as set out in note 
18. Shares issued under the scheme may  be sold at the expiration of any Restriction Agreement between the eligible employee and the 
Company. Such restrictions may be imposed by the remuneration committee upon the grant of options under the option plan and such 
restrictions will be contained in the Option Agreement between the eligible employee and the Company. In all other respects the shares 
rank equally with other fully paid ordinary shares on issue (refer to note 18(c)).

(B) JP MORGAN SECURITIES AUSTRALIA LIMITED DEED 

In part consideration for underwriting services in relation to the IPO, the Company granted JP Morgan Securities Australia Limited 
322,181 options to purchase 322,181 ordinary shares in the Company. These options vested on 25 November 2007 and have a three year 
term through to 25 May 2010, with the option exercise price being $2.20.

www.qrxpharma.com  69

 
QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

28  SHARE-BASED PAYMENTS (CONTINUED)

(C) SET OUT BELOW ARE SUMMARIES OF OPTIONS GRANTED UNDER THE PLANS:

Grant Date

Expiry date

Exercise 
price

Balance at 
start of the 
year

Granted 
during the 
year

Exercised 
during the 
year

Cashless 
options 
exercised 
during the 
year

Balance at 
end of the 
year

Vested and 
exercisable 
at end of 
the year

Number

Number

Number

Number

Number

Number

Consolidated and parent   2008

31 March 2007
14 April 2007
25 May 2007
25 May 2007
25 May 2007
1 September 2007
1 October 2007
9 October 2007
1 January 2008
1 April 2008
1 April 2008

Total

31 March 2014
14 April 2014
25 May 2014
25 May 2014
25 May 2010
1 September 2014
1 October 2014
9 October 2014
1 January 2015
1 April 2015
1 April 2015

$1.42
$1.00
$2.00
$1.00
$2.20
$1.70
$1.45
$1.34
$1.11
$1.05
$1.04

402,726
2,819,082
1,448,450
552,726
322,181
-
-
-
-
-
-

-
-
-
-
-
50,000
75,000
50,000
350,000
600,000
75,000

5,545,165

1,200,000

Weighted average exercise price

$1.36

$1.13

-
-
-
-
-
-
-
-
-
-
-

-

-

-
(805,452)
-
-
-
-
-
-
-
-
-

402,726
2,013,630
1,448,450
552,726
322,181
50,000
75,000
50,000
350,000
600,000
75,000

134,242
671,210
482,817
184,242
322,181
-
-
-
-
-
-

(805,452)

5,939,713

1,794,692

$1.00

$1.36

$1.42

70  QRxPharma  Annual Report 2008

(C) SET OUT BELOW ARE SUMMARIES OF OPTIONS GRANTED UNDER THE PLANS (CONTINUED):

Grant Date

Expiry date

Exercise 
price

Balance at 
start of the 
year

Granted 
during the 
year

Exercised 
during the 
year

Forfeitted 
during the 
year

Balance at 
end of the 
year

Vested 
and exer-
cisable at 
end of the 
year

Number

Number

Number

Number

Number

Number

Consolidated and parent   2007

19 December 2002
19 February 2003
1 December 2003
24 February 2004
24 February 2004
24 February 2004
25 February 2004
16 March 2004
19 May 2004
24 June 2004
13 July 2004
14 July 2004
17 August 2004
19 October 2004
19 February 2005
18 May 2005
21 September 2005
31 March 2007
14 April 2007
25 May 2007
25 May 2007
25 May 2007

Total

19 December 2012
19 February 2008
1 December 2006
24 February 2013
24 February 2014
24 February 2014
24 February 2014
16 March 2014
19 May 2014
24 June 2014
13 July 2014
14 July 2014
17 August 2014
19 October 2014
19 February 2015
18 May 2015
21 September 2015
31 March 2014
14 April 2014
25 May 2014
25 May 2014
25 May 2010

$0.30
$0.15
$0.15
$0.15
$0.30
$0.15
$0.15
$0.15
$0.15
$0.15
$0.15
$0.15
$0.15
$0.15
$0.15
$0.15
$0.15
$1.42
$1.00
$2.00
$1.00
$2.20

40,000
40,000
20,000
10,000
10,000
6,875
5,000
10,000
25,000
20,000
50,000
40,000
20,000
784,248
150,000
240,000
110,000
-
-
-
-
-

-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
402,726
2,819,082
1,448,450
552,726
322,181

-
(40,000)
(20,000)
(9,124)
-
-
-
(10,000)
(25,000)
-
(50,000)
-
-
(364,192)
-
(240,000)
(45,000)
-
-
-
-
-     

(40,000)
-
-
(876)
(10,000)
(6,875)
(5,000)
-
-
(20,000)
-
(40,000)
(20,000)
(420,056)
(150,000)
-
(65,000)
-
-
-
-
-     

-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
402,726
2,819,082
1,448,450
552,726
322,181

1,581,123

5,545,165

(803,316)

(777,807)

5,545,165

Weighted average exercise price

$0.15

$1.36

$0.15

$0.15

$1.36

The net shares issued upon exercising of cashless options was 653,640 (refer note 18(b)).

-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-     

-

$-

During the year ended 30 June 2007, 509,325 shares were also issued as certain options carried anti dilution provisions (refer to note 
18(b)).

No options expired during the periods covered by the above tables.

The weighted average remaining contractual life of share options outstanding at the end of the period was 5.8 years (2007 – 7.0 years).

www.qrxpharma.com  71

QRxPHARMA LIMITED ABN 16 102 254 151
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

28  SHARE-BASED PAYMENTS (CONTINUED)

Fair value of options granted

The assessed fair value at grant date of options granted during the year ended 30 June 2008 was $0.69 per option (2007: $1.46). The 
fair value at grant date is independently determined using a Black Scholes option pricing model that takes into account the exercise 
price, the term of the option, the impact of dilution, the share price at grant date and expected price volatility of the underlying share, the 
expected dividend yield and the risk free interest rate for the term of the option.

The model inputs for options granted during the year ended 30 June 2008 included:

(a)  exercise price: $1.04 to $1.70 (2007 – $1.00 to $2.20)

(b)  grant date: 1 September 2007, I October 2007, 9 October 2007, 1 January 2008 and 1 April 2008 (2007 – 31 March 2007, 

  14 April 2007, 25 May 2007)

(c)  expiry date: 1 September 2014, 1 October 2014, 9 October 2014, 1 January 2015 and 1 April 2015 (2007 – 31 March 2014, 

  14 April 2014, 25 May 2010, 25 May 2014) 

(d)  share price at grant date: $1.04 to $1.70 (2007 – $2.00)

(e)  expected price volatility of the company’s shares: 60% (2007 – 60%)

(f)   expected dividend yield: nil% (2007 – nil%)

(g)  risk free interest rate: 6.25% (2007 – 6.25%).

The expected price volatility is based on the historic volatility (based on the remaining life of the options), adjusted for any expected 
changes to future volatility due to publicly available information.

(D)  EXPENSES ARISING FROM SHARE-BASED PAYMENT TRANSACTIONS

Total expenses arising from share-based payment transactions recognised during the period as part of employee benefi t expense were 
as follows:

Options issued under employee option plan
Options issued under anti dilution provisions

Consolidated

Parent

2008

$’000

3,327
-

3,327

2007

$’000

          149
    76

225

2008

$’000

2,506
-

2,506

2007

$’000

          149
            76

225

29  EVENTS OCCURRING AFTER THE BALANCE SHEET DATE

No signifi cant events have occurred after the balance sheet date which would have a material impact on the fi nancial results of the Group.

72  QRxPharma  Annual Report 2008

 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
DIRECTORS’ DECLARATION
FOR THE YEAR ENDED 30 JUNE 2008

In the directors’ opinion:

(a) 

the fi nancial statements and notes set out on pages 31 to 72 are in accordance with the Corporations Act 2001, including:

(i) complying with Accounting Standards, the Corporations Regulations 2001 and other mandatory professional reporting  

requirements; and

(ii) giving a true and fair view of the company’s and consolidated entity’s fi nancial position as at 30 June 2008 and of their   
  performance for the fi nancial year ended on that date; and

(b) 

there are reasonable grounds to believe that  the company will be able to pay its debts as and when they become due and payable;  

  and

(c) 

the audited remuneration disclosures set out on pages 14 to 21 of the directors’ report comply with Accounting Standards AASB    

  124 Related Party Disclosures and the Corporations Regulations 2001.

The directors have been given the declarations by the chief executive offi cer and chief fi nancial offi cer required by section 295A of the 
Corporations Act 2001.

This declaration is made in accordance with a resolution of the directors.

Peter C Farrell  
Director   

Sydney
25 August 2008

www.qrxpharma.com  73

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
AUDIT REPORT
FOR THE YEAR ENDED 30 JUNE 2008

PricewaterhouseCoopers
ABN 52 780 433 757
Darling Park Tower 2
201 Sussex Street
GPO BOX 2650
SYDNEY NSW 1171
DX 77 Sydney
Australia
www.pwc.com/au
Telephone +61 2 8266 0000
Facsimile +61 2 8266 9999

INDEPENDENT AUDITOR’S REPORT 
TO THE MEMBERS OF QRxPHARMA LIMITED

Report on the fi nancial report 

We have audited the accompanying fi nancial report of QRxPharma Limited (the company), which
comprises the balance sheet as at 30 June 2008, and the income statement, statement of changes
in equity and cash fl ow statement for the year ended on that date, a summary of signifi cant
accounting policies, other explanatory notes and the directors’ declaration for both QRxPharma
Limited and the QRxPharma Group (the consolidated entity). The consolidated entity comprises the
company and the entities it controlled at the year’s end or from time to time during the fi nancial
year.

Directors’ responsibility for the fi nancial report

The directors of the company are responsible for the preparation and fair presentation of the
fi nancial report in accordance with Australian Accounting Standards (including the Australian
Accounting Interpretations) and the Corporations Act 2001. This responsibility includes establishing
and maintaining internal controls relevant to the preparation and fair presentation of the fi nancial
report that is free from material misstatement, whether due to fraud or error; selecting and applying
appropriate accounting policies; and making accounting estimates that are reasonable in the
circumstances. In Note 1, the directors also state, in accordance with Accounting Standard
AASB 101 Presentation of Financial Statements, that compliance with the Australian equivalents to
International Financial Reporting Standards ensures that the fi nancial report, comprising the
fi nancial statements and notes, complies with lnternational Financial Reporting Standards.

Auditor’s responsibility 

Our responsibility is to express an opinion on the fi nancial report based on our audit. We conducted
our audit in accordance with Australian Auditing Standards. These Auditing Standards require that
we comply with relevant ethical requirements relating to audit engagements and plan and perform
the audit to obtain reasonable assurance whether the fi nancial report is free from material
misstatement.

Liability limited by a scheme approved under Professional Standards Legislation

74  QRxPharma  Annual Report 2008

An audit involves performing procedures to obtain audit evidence about the amounts and
disclosures in the fi nancial report. The procedures selected depend on the auditor’s judgement,
including the assessment of the risks of material misstatement of the fi nancial report, whether due
to fraud or error. In making those risk assessments, the auditor considers internal control relevant
to the entity’s preparation and fair presentation of the fi nancial report in order to design audit
procedures that are appropriate in the circumstances, but not for the purpose of expressing an
opinion on the effectiveness of the entity’s internal control. An audit also includes evaluating the
appropriateness of accounting policies used and the reasonableness of accounting estimates
made by the directors, as well as evaluating the overall presentation of the fi nancial report.

Our procedures include reading the other information in the Annual Report to determine whether it
contains any material inconsistencies with the fi nancial report.

For further explanation of an audit, visit our website http://www.pwc.com/au/fi nancialstatementaudit.

Our audit did not involve an analysis of the prudence of business decisions made by directors or
management.

We believe that the audit evidence we have obtained is suffi cient and appropriate to provide a
basis for our audit opinions.

Independence

In conducting our audit, we have complied with the independence requirements of the Corporations 
Act 2001.

Auditor’s opinion 

In our opinion:

(a) 

the fi nancial report of QRxPharma Limited is in accordance with the Corporations  
Act 2001, including:

(i) 

(ii) 

giving a true and fair view of the company’s and consolidated entity’s  
fi nancial position as at 30 June 2008 and of their performance for the year  
ended on that date; and 

complying with Australian Accounting Standards (including the Australian  
Accounting Interpretations) and the Corporations Regulations 2001; and

(b) 

the fi nancial report also complies with International Financial Reporting Standards as
disclosed in Note 1.

www.qrxpharma.com  75

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
AUDIT REPORT (CONTINUED)
FOR THE YEAR ENDED 30 JUNE 2008

Report on the Remuneration Report

We have audited the Remuneration Report included in pages 14 to 21 of the directors’ report for
the year ended 30 June 2008. The directors of the company are responsible for the preparation
and presentation of the Remuneration Report in accordance with section 300A of the Corporations
Act 2001. Our responsibility is to express an opinion on the Remuneration Report, based on our
audit conducted in accordance with Australian Auditing Standards. 

Auditor’s opinion 

In our opinion, the Remuneration Report of QRxPharma Limited for the year ended 30 June 2008,
complies with section 300A of the Corporations Act 2001.

Matters relating to the electronic presentation of the audited fi nancial report

This auditor’s report relates to the fi nancial report and remuneration report of QRxPharma Limited
(the company) for the year ended 30 June 2008 included on QRxPharma Limited web site. The
company’s directors are responsible for the integrity of the QRxPharma Limited web site. We have
not been engaged to report on the integrity of this web site. The auditor’s report refers only to the
fi nancial report and remuneration report named above. It does not provide an opinion on any other
information which may have been hyperlinked to/from these statements or the remuneration report.
If users of this report are concerned with the inherent risks arising from electronic data
communications they are advised to refer to the hard copy of the audited fi nancial report and
remuneration report to confi rm the information included in the audited fi nancial report and
remuneration report presented on this web site.

PricewaterhouseCoopers

Manoj Santiago 
Partner 

76  QRxPharma  Annual Report 2008

Sydney
25 August 2008

 
 
 
 
 
 
 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
SHAREHOLDER INFORMATION
THE SHAREHOLDER INFORMATION SET OUT BELOW WAS APPLICABLE AS AT 29 AUGUST 2008.

A.  DISTRIBUTION OF EQUITY SECURITIES

Analysis of numbers of equity security holders by size of holding:

1 – 1000
1,001 – 5,000
5,001 – 10,000
10,001 – 100,000
100,001  and over

Shares

Options

48
228
187
228
57

748

-
-
-
10
14

24

There are 7 holders of less than a marketable parcel of ordinary shares.

B.  EQUITY SECURITY HOLDERS

Twenty largest quoted equity security holders

The names of the twenty largest holders of quoted equity securities are listed below:

Name

HSBC Custody Nominees (Australia) Limited
Dr John Holaday and Holaday Foundation
Nanyang Financial Services Limited
Innovation Capital Limited
National Nominees Limited
Spring Ridge Ventures I, LP
Uniquest Pty Limited
Dr Gary Pace
Innovation Capital LLC
ANZ Nominees Limited
UIIT Pty Limited
Ecapital Nominees Pty Limited
Bacchus Global Assets LLC
Dr Peter Farrell
Citicorp Nominees Pty Limited
Innovation Capital QRX Trust
Lynx No1 Pty Limited
Mr David Stack
Gowing Brothers Limited
Irrewarra Investments Pty Ltd

Ordinary shares

Number held

Percentage of issued 
shares

10,139,834
7,543,000
5,925,586
5,269,090
4,582,052 
 4,228,673
4,004,499 
3,230,083 
2,713,685
2,518,495
2,175,338 
1,800,000 
1,380,366
1,280,540 
1,053,914
992,793
877,853    
525,895
400,000
395,200

61,036,896

13.52%
10.06%
7.90%
7.03%
6.11%
 5.64%
5.34%
4.31%
3.62%
3.36%
2.90%
2.40%
1.84%
1.71%
1.41%
1.32%
1.17%
0.70%
0.53%
0.53%

81.38%

www.qrxpharma.com  77

 
 
 
 
 
QRxPHARMA LIMITED ABN 16 102 254 151
SHAREHOLDER INFORMATION (CONTINUED)
THE SHAREHOLDER INFORMATION SET OUT BELOW WAS APPLICABLE AS AT 29 AUGUST 2008.

B.  EQUITY SECURITY HOLDERS (CONTINUED)

Unquoted equity securities

Options issued under the QRxPharma Limited Employee Share Option Plan and 
JP Morgan Securities Australia Limited Deed to take up ordinary shares

5,939,713*

24**

Number on issue

Number of holders

* Number of unissued ordinary shares under the options. 
** No person holds 20% or more of these securities.

Escrowed ordinary shares and options

The following ordinary shares are subject to voluntary escrow:
For the period through to 25 May 2009

  34,229,407***

*** 10,461,317 of these ordinary shares are also subject to ASX escrow for the same period

C.  SUBSTANTIAL HOLDERS

Substantial holders in the company are set out below:

Ordinary shares

Innovation Capital Limited and Innovation Capital LLC
Dr John W Holaday and Holaday Foundation
Nanyang Financial Services Limited
Westpac Banking Corporation
Spring Ridge Ventures I, LP
Uniquest Pty Limited

Number held

Percentage

7,982,775
7,543,000
5,925,586 
4,928,247
4,228,673
4,004,499

10.64%
10.06%
7.90%
6.57%
5.64%
5.34%

D.  VOTING RIGHTS

The voting rights attaching to each class of equity securities are set out below:

(a)  Ordinary shares

  On a show of hands every member present at a meeting in person or by proxy shall have one vote and upon a poll each share shall  
  have one vote.

(b)  Options

  No voting rights.

78  QRxPharma  Annual Report 2008

 
 
 
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www.qrxpharma.com  79

80  QRxPharma  Annual Report 2008

www.qrxpharma.com