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Viveve Medical

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FY2017 Annual Report · Viveve Medical
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549

FORM 10-K

(Mark One)

   ☒

ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the fiscal year ended  December 31, 2017

or

   ☐

TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from _______________.to _______________.

Commission file number 1-11388

VIVEVE MEDICAL, INC.
(Exact name of Registrant as specified in its charter)

Delaware
(State or other jurisdiction of incorporation or organization)

04-3153858
(I.R.S. Employer Identification No.)

345 Inverness Drive South
Building B, Suite 250
Englewood, CO 80112
 (Address of principal executive offices - Zip Code)

Registrant's telephone number, including area code: (720)-696-8100

Securities registered pursuant to Section 12(b) of the Act:  

Title of each class

Name of each exchange on which registered

Common Stock, par value $0.0001 per share

The Nasdaq Capital Market

Securities registered pursuant to Section 12(g) of the Act:   None.

Indicate by check mark if the Registrant is a well-known seasoned issuer as defined in Rule 405 of the Securities Act. Yes  ☐    No   ☒

Indicate by check mark if the Registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes ☐    No   ☒

Indicate by check mark whether the Registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the  Securities
Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the Registrant was required to file such reports),
and (2) has been subject to such filing requirements for the past 90 days. Yes ☒    No ☐

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
   
 
 
 
 
 
Indicate by check mark whether the Registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive
Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§ 232.405 of this chapter) during the preceding 12
months (or for such shorter period that the Registrant was required to submit and post such files). Yes ☒    No ☐

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and wi ll not be
contained, to the best of the Registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of
this Form 10-K or any amendment to this Form 10-K. ☒

Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting
company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting
company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act. (Check one): 

Large accelerated filer ☐

Accelerated filer ☒

Non-accelerated filer ☐ (Do not check if a smaller reporting
company)

Smaller reporting company ☒

Emerging growth company ☐

If  an  emerging  growth  company,  indicate  by  check  mark  if  the  registrant  has  elected  not  to  use  the  extended  transition  period  for
complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Indicate by check mark whether the Registrant is a shell company (as defined by Rule 12b-2 of the  Act). Yes ☐    No   ☒

As  of June  30,  2017,  the  aggregate  market  value  of  the  voting  and  non-voting  common  equity  held  by  non-affiliates  of  the
Registrant, based on the last reported sales price of the Registrant’s common stock, par value $0.0001 per share, on The Nasdaq Capital
Market on such date, was approximately $93,750,710.

Number of shares outstanding of the Registrant’s common stock, as of March 8, 2018: 31,233,972

DOCUMENTS INCORPORATED BY REFERENCE

Portions of the registrant’s definitive proxy statement for its 2018 Annual Meeting of Stockholders, which the registrant intends to file
with the Securities and Exchange Commission pursuant to Regulation 14A within 120 days after the end of the registrant’s fiscal year
ended December 31, 2017, are incorporated by reference into Part III of this Annual Report on Form 10-K. 

 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
   
 
 
 
VIVEVE MEDICAL, INC.

Table of Contents

Part I

Business
Risk Factors
Unresolved Staff Comments
Properties
Legal Proceedings
Mine Safety Disclosures

Part II

Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities
Selected Financial Data
Management’s Discussion and Analysis of Financial Condition and Results of Operations
Quantitative and Qualitative Disclosure about Market Risk
Financial Statements and Supplementary Data
Changes in and Disagreements with Accountants on Accounting and Financial Disclosures
Controls and Procedures
Other Information

Part III

Item 1
Item 1A
Item 1B
Item 2
Item 3
Item 4

Item 5
Item 6
Item 7
Item 7A
Item 8
Item 9
Item 9A
Item 9B

Item 10
Item 11
Item 12
Item 13
Item 14

Directors, Executive Officers and Corporate Governance
Executive Compensation
Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters
Certain Relationships and Related Transactions, and Director Independence
Principal Accountant Fees and Services

Item 15

Exhibits, Financial Statement Schedules

Signatures

Part IV

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Unless otherwise noted, the terms “ Viveve”, “the Company,” “we,” “us,” “our” and similar designations in this Annual Report on Form
10-K refer to Viveve Medical, Inc. and its wholly-owned subsidiaries, Viveve, Inc. and Viveve BV.

PART I

FORWARD-LOOKING STATEMENTS

This report contains forward-looking statements. Forward-looking statements give our current expectations or forecasts of future
events. You can identify these statements by the fact that they do not relate strictly to historical or current  facts. You can find many (but
not  all)  of  these  statements  by  looking  for  words  such  as  “approximates,”  “believes,”  “hopes,”  “expects,”  “anticipates,”  “estimates,”
“projects,” “intends,” “plans,” “would,” “should,” “could,” “may” or other similar expressions in this report. In particular, forward-looking
statements  include  statements  relating  to  future  actions,  prospective  products,  applications,  customers  and  technologies,  and  future
performance  or  future  financial  results.  These  forward-looking  statements  are  subject  to  certain  risks  and  uncertainties  that  could  cause
actual results to differ materially from our historical experience and our present expectations or projections. Factors that could cause actual
results to differ from those discussed in the forward-looking statements include, but are not limited to:

●
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our limited cash and our history of losses;
our ability to achieve profitability;
our limited operating history;
emerging competition and rapidly advancing technology;
whether  we  are  successful  in  having  our  medical  device  approved  or  cleared  for  sale  by  the  U.S.  Food  and  Drug
Administration (“FDA”) for all indications;
whether demand develops for our medical device;
the impact of competitive or alternative products, technologies and pricing;
the  adequacy  of  protection  afforded  to  us  by  the  patents  that  we  own  and  the  cost  to  us  of  maintaining,  enforcing  and
defending those patents;
our ability to obtain, expand and maintain protection in the future, and to protect our non-patented intellectual property;
our exposure to and ability to defend third-party claims and challenges to our patents and other intellectual property rights;
our ability to obtain adequate financing in the future, as and when we need it;
our ability to continue as a going concern;
our success at managing the risks involved in the foregoing items; and

●
●
●
●
●
● other factors discussed in this report

Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future
results,  levels  of  activity,  performance  or  achievements.  The  forward-looking  statements  are  based  upon  management’s  beliefs  and
assumptions  and  are  made  as  of  the  date  of  this  report.  We  undertake  no  obligation  to  publicly  update  or  revise  any  forward-looking
statements included in this report to conform such statements to actual results or changes in our expectations. You should not place undue
reliance on these forward-looking statements.

Item 1. Business

Viveve  designs,  develops,  manufactures  and  markets  a  platform  medical  technology,  which  we  refer  to  as  Cryogen-cooled
Monopolar RadioFrequency, or CMRF. Our proprietary CMRF technology is delivered through a radiofrequency generator, handpiece and
treatment  tip,  that  collectively,  we  refer  to  as  the  Viveve  System ®.  The  Viveve  System  is  currently  being  marketed  around  the  world
(outside  of  the  United  States)  for  the  non-invasive  treatment  of  various  post-partum  conditions  including  vaginal  introital  laxity,  for
improved sexual function, and for vaginal rejuvenation, depending on the relevant country-specific clearance or approval, that we refer to
as the Geneveve™ treatment.

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At  this  time, the  Viveve  System  is  indicated  for  use  and  being  marketed  for  use  in  general  surgical  procedures  for
electrocoagulation and hemostasis in the United States, but the device has not been cleared or approved for use for the treatment of vaginal
laxity, to improve sexual function, or for vaginal rejuvenation in the United States. Accordingly, the Company is prohibited under current
U.S. regulations from promoting it to physicians or consumers for these unapproved uses.  

We believe  the Viveve System, that delivers the Geneveve treatment, provides a number of benefits for physicians and patients,

including:

● a safe, minimally-invasive, non-ablative alternative to surgery;
● it requires only a single treatment;
● compelling physician economics; and
● ease of use.

In  North America,  which  includes  the  U.S.  and  Canada,  the  Viveve  System  is  sold  through  a  direct  sales  force.  In  most  other

regions, we market and sell through an extensive network of distribution partners.

Currently, the Viveve System is cleared for marketing in 62 countries throughout the world under the following indications for

use:

 Indication for Use:

 General Surgical procedures for electrocoagulation and hemostasis

 For treatment of vaginal laxity
 For treatment of the vaginal introitus, after vaginal childbirth, to improve sexual function
 For vaginal rejuvenation

  No. of Countries:  
 (including the
U.S.)

  3

  41
  17
  1

The Viveve System is comprised of three main components: a radio frequency generator housed in a table-top console; a reusable
handpiece; and a single-use treatment tip. Single-use accessories (e.g. RF return pad, coupling fluid), a foot pedal and a cryogen canister
that can be used for approximately four to five procedures are also included with the System. Practitioners attach the single-use treatment
tip to the handpiece. The generator then authenticates the treatment tip and programs the system for the desired treatment without further
physician intervention. The treatment is performed in a physician’s office and does not require the use of anesthesia. The tissue remodeling
effect resulting from the Geneveve treatment has been demonstrated by our pre-clinical and clinical research.

Our goal is to become the leading provider of non-invasive solutions to treat certain women’s intimate health conditions by:

● Broadening  the  conditions  we  treat  through robust  clinical  trials  and regulatory label expansion.  In  addition  to  pursuing
clearance/approval  in  the  U.S.  for  the  improvement  of  sexual  function,  we  intend  to  conduct  several  clinical  trials,  and  if
successful, submit for regulatory clearance/approval in the U.S. and abroad for mild-to-moderate stress urinary incontinence
and potentially vulvovaginal atrophy.

● Increasing  the  Number  of  Installed  Base  of  Viveve  Systems.  In  our  existing  markets,  we  plan  to  (i)  expand  the  number  of
Viveve  Systems  by  leveraging  our  current  and  future  clinical  study  results  and  through  innovative  marketing  programs
directed at both physicians and patients, where permissible by law, and (ii) expand our efforts and obtain regulatory approvals
in additional markets, although there are no assurances that we will ever receive such approvals.

● Driving Increased Treatment Tip Usage. We work collaboratively with our physician customer base to increase treatment tip
usage  by  enhancing  customer  awareness  and  facilitating  the  marketing  efforts  of  our  physician  customers  to  their  patients,
where  permitted  by  law.  We  intend  to  launch  innovative  marketing  programs  with  physician  customers  to  develop  a
profitable Geneveve practice. In addition, we plan to incorporate practice development managers into our sales organization
to support our physician customers.

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● Broadening Our Physician Customer Base. While our initial focus is on marketing our procedure to the OB/GYN specialty,
we  intend  to  selectively  expand  our  sales  efforts  into  other  physician  specialties,  such  as  plastic  surgery,  dermatology,
urology, urogynecology, general surgery and family practice. Additionally, we intend to pursue sales from physician-directed
medi-spas with track records of safe and successful aesthetic treatments.

● Developing New Treatment Tips and System Enhancements. We intend to continue to expand our line of treatment tips to
allow  for  even  shorter  procedure  times  to  benefit  both  physicians  and  patients.  We  also  plan  to  pursue  potential  system
modifications and next generation enhancements that will further increase the ease-of-use of the Viveve System.

● Investing in Intellectual Property and Patent Protection. We will continue to defend and invest in expanding our intellectual

property portfolio, and we intend to file for additional patents to strengthen our intellectual property rights.

As  of  December  31,  2017,  we  have  sold  444  Viveve  Systems  and  approximately  14,875   single-use  treatment  tips  in  countries

outside of the U.S.

On  September  23,  2014,  Viveve  Medical,  Inc.  (formerly  PLC  Systems,  Inc.),  a  Delaware  corporation  (“Viveve  Medical”,
“Viveve”, “we”, “us” or “our”) completed a reverse acquisition and recapitalization pursuant to the terms and conditions of an Agreement
and Plan of Merger (the “Merger Agreement”) by and among PLC Systems Acquisition Corp., a wholly owned subsidiary of PLC Systems
Inc., with and into Viveve, Inc., a Delaware corporation (the “Merger”). In conjunction with the Merger, we changed our name from PLC
Systems  Inc.  to  Viveve  Medical,  Inc.  to  better  reflect  our  new  business.  Viveve  Medical  competes  in  the  women’s  health  industry  by
marketing the Viveve System and its Geneveve treatment as a way to improve the overall sexual well-being and quality of life of women
suffering from vaginal laxity, depending on the relevant country-specific clearance or approval. We are currently located at 345 Inverness
Drive South, Building B, Suite 250, Englewood, Colorado 80206 and our telephone number is (720) 696-8100. We relocated the corporate
headquarters to Englewood, Colorado in June of 2017 as discussed in Part II – Item 7. Management’s Discussion and Analysis of Financial
Condition and Results of Operations – Recent Events. Our website can be accessed at www.viveve.com. The information contained on or
that may be obtained from our website is not a part of this report. Viveve, Inc. operates as a wholly-owned subsidiary of Viveve Medical
and was incorporated in 2005.

Our Products

The Viveve System

The Viveve System is comprised of three main components: a radiofrequency generator housed in a table-top console; a reusable
handpiece; and a single-use treatment tip. Single-use accessories (e.g. RF return pad, coupling fluid), a foot pedal and cryogen canister for
approximately four to five procedures also included with System. Physicians or medical practitioners attach the single-use treatment tip to
the handpiece, which is connected to the console. The generator authenticates the treatment tip and programs the system for the desired
Geneveve treatment without further physician intervention.

● Radiofrequency Generator. The generator produces a six-megahertz signal and is simple and efficient to operate. Controls are
within  easy  reach,  and  important  user  information  is  clearly  displayed  on  the  console’s  built-in  display,  including  energy
delivered,  tissue  impedance,  duration  and  feedback  on  procedure  technique.  Cooling  is  achieved,  in  conjunction  with  the
generator, through the delivery of a coolant that helps to cool and protect the mucosa during a procedure.

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● Handpiece.  The  reusable  handpiece  holds  the  treatment  tip  in  place  and  processes  information  about  temperature,  contact,
cooling  system  function  and  other  important  data. A  precision  control  valve  within  the  handpiece  meters  the  delivery  of
coolant, which protects the mucosal surface.

● Treatment Tip.  The  single-use  treatment  tip  is  available  in  two  sizes  and  comes  pre-sterilized.  Each  treatment  tip  contains
a  proprietary  internal  EEPROM  or  Electrically  Erasable  Programmable  Read-Only  Memory  chip,  which  stores  treatment
parameters  and  safety  limits  in  order  to  optimize  performance  and  safety.  To  enhance  procedural  safety,  we  have
programmed  the  EEPROM  for  single-use  treatments.  Using  the  same  treatment  tip  to  perform  multiple  procedures  could
result in injury, therefore, the EEPROM disables the treatment tip after a pre-programmed number of pulses to ensure that the
treatment tip is not reused.

The Viveve System also includes other consumable components. The console houses a canister of coolant that can be used for
approximately  four  to  five  procedures.  Each  procedure  requires  a  new  return  pad,  which  is  typically  adhered  to  the  patient’s  thigh  or
buttocks to allow a path of travel for the RF current through the body and back to the generator. We also sell proprietary single-use bottles
of coupling fluid, a viscous liquid that helps ensure electrical and thermal contact with the treatment tip.

Technology Platform - Cryogen-cooled Monopolar Radiofrequency (CMRF)

The  Viveve  System  uses  a  patented  and  proprietary  method  of  delivering  monopolar  radiofrequency  (RF)  energy  for  treating

tissue:

tissue:

● Monopolar Radiofrequency Energy. Monopolar RF delivery uses an active electrode applied to the target tissue and a passive
return electrode adhered to the patient’s thigh or buttocks. RF current is concentrated where the active electrode touches the
body and expands as it is drawn through progressively deeper layers of tissue toward the return electrode. Providing both
precise placement and deep energy penetration, the monopolar arrangement draws higher levels of therapeutic energy into
deeper  tissue  layers  than  competing  bipolar  arrangements  that  rely  on  passive  dispersion  of  current  passing  between  two
closely spaced electrodes on the tissue surface.

● Capacitive  Coupling  Mechanism  of  Action  for  Collagen  Heating.  Our  single-use  Viveve  treatment  tip  contains  patented
technology  that  uses  monopolar  RF  energy  as  a  controlled  tissue  heating  source  through  the  use  of  a  non-conducting
material, known as a dielectric. Capacitive coupling is the use of the dielectric to create an electric field in the area where the
treatment  tip  touches  the  body.  The  electric  field  induces  a  current  within  the  surrounding  tissue,  resulting  in  volumetric
heating  of  the  tissue  due  to  the  tissue’s  natural  resistance  to  electrical  current  flow.  Collagen  is  an  efficient  conductor  of
electricity and therefore acts as a pathway for the electric current. This process results in heating of the fibrous septae, the
strands of collagen fibers that permeate tissues and connect the outer mucosal layer to the underlying muscle. Delivery of
heat  to  the  fibrous  septae  located  in  deeper  layers  of  the  tissue  shrinks  and  shortens  them,  resulting  in  tightening  of  the
mucosal tissue. Over one to three months, as part of the body’s natural response to the activation of fibroblasts that results
from the application of low-energy hyperthermic RF energy, damaged collagen is reorganized into stronger, tighter bundles
and can be supplemented with new collagen. This renewal of the tissue support matrix leads to improved tissue integrity and
function.

The  Viveve  System  also uses a proprietary, controlled cryogen surface cooling that enables deep volumetric heating of vaginal

● Reverse Thermal Gradient.  With  radiofrequency  delivery,  it  is  typical  to  expect  higher  temperatures  closest  to  the  surface
electrode and a comparatively lower temperature distal to the electrode. However, with the Viveve System the opposite is
true,  hence  a  “reverse”  thermal  gradient.  Maintaining  a  well-cooled,  protected  surface  allows  our  treatment  tips  to  safely
remain  on  the  tissue  longer,  allowing  an  optimal  amount  of  RF  energy  penetration  into  the  deeper  tissue  layers,  while
helping to ensure a comfortable patient experience.

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● Algorithmically-controlled Cryogen Delivery. The Viveve System software actively monitors the temperature of the surface
tissue and delivers the appropriate amount of cryogen necessary to keep the surface near normal body temperature. It does so
consistently,  automatically  and  completely  independently  of  the  actions  of  the  operator,  providing  an  important  built-in
safety mechanism to protect the delicate surface of vaginal tissue.

Market Overview

Overview of Vaginal Laxity and Sexual Function

Vaginal laxity and tissue architecture have often been overlooked as contributing etiological factors to female sexual dysfunction.
Vaginal laxity can lead to diminished physical sensation during intercourse. This reduction in sensation is often coupled with a reduction in
sexual satisfaction, all of which can also impact a woman’s sense of sexual self-esteem and her relationship with her sexual partner.

Vaginal laxity is rarely discussed in the clinical situation, yet most surveyed OB/GYNs and urogynecologists recognize that it is
an  underreported,  yet  bothersome,  medical  condition  that  impacts  relationship  happiness  and  sexual  function.1  Another  survey  of
OB/GYNs,  found  that  vaginal  laxity  is  the  most  frequent  physical  change  seen  or  discussed  post-vaginal  delivery2. Additionally,  in  a
survey of women ranging from 25-45 years of age, who had experienced at least one vaginal delivery, approximately half expressed some
degree of concern over “looseness” of the vaginal introitus.3

Women can develop vagin al laxity for a number of reasons, including aging, genetic predisposition, lifestyle, and/or trauma. As
women age, slower cellular renewal coupled with reduced vascular and glandular networks contributes to loss of underlying supportive
fibrous  tissue.  Some  women  may  have  underlying  pathophysiological  issues  with  collagen  formation,  remodeling  and  repair;  and  their
lifestyle  choices  (e.g.,  alcohol  consumption,  tobacco  use,  and  excessive  food  consumption)  also  play  a  role  in  the  integrity  of  vaginal
tissue. Vaginal trauma (e.g., childbirth, surgery, self-stimulation, or coitus) can also contribute to vaginal laxity.

All  women  who  have  given  birth  vaginally  undergo  stretching  of  the  tissues  of  the  vaginal  opening  to  accommodate  the  fetal
head.  Often  the  effects  are  permanent  and  many  women  have  long-term  physical  and  psychological  consequences  including  sexual
dissatisfaction. One significant issue is the loosening of the introitus ─ the vaginal opening. This happens with the first vaginal delivery
and usually is made worse with subsequent vaginal deliveries. Vaginal laxity can result in decreased sexual pleasure for both women and
their partners during intercourse. We believe that this condition is not frequently discussed because women are embarrassed, fear that their
concerns will be dismissed or fear that their physicians will not understand. Physicians hesitate to discuss the situation with their patients
because  historically  there  has  been  no  safe  and  effective  treatment.  Physicians  frequently  recommend  Kegel  exercises.  However,  these
exercises  only  strengthen  the  pelvic  floor  muscles  and  do  not  address  the  underlying  cause  of  vaginal  laxity  –  loss  of  tissue  elasticity.
While surgery can be performed to tighten the vaginal canal, the formation of scar tissue from the surgery may lead to painful intercourse
and permanent side effects.

As a consequence of the physical tissue damage that can result from childbirth, a significant decrease in sexual satisfaction has
been  reported  in  women  who  underwent  vaginal  delivery,  when  assessed  two  years  after  delivery,  in  comparison  with  those  who
underwent  elective  caesarian  section.  In  the  past  several  years  there  has  been  a  marked  increase  in  the  number  of  women  requesting
delivery by caesarian section with the intention of preventing damage to the pelvic floor and introitus. Caesarian sections are not without
risk to both the baby and mother. Whether or not to agree to a woman’s request for an elective caesarian section has generated considerable
controversy  among  obstetricians.  If  a  procedure  were  available  to  address  the  concerns  of  women  about  vaginal  laxity,  we  believe  the
perceived need to have a caesarian section to prevent vaginal tissue damage may decrease significantly.

1 Pauls RN, Fellner AN, Davila GW. Vaginal laxity: a poorly understood quality of life problem; a survey of physician members of the
International Urogynecological Association (IUGA). Int Urogynecol J. 2012 Oct;23(10):1435-48.

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2 Lukes A, Kingsberg S. OB/GYNs Attitudes and Perceptions Regarding Sexual Health of Patients After Delivery. Poster at ISSWSH
Annual Meeting. 2010.

3 Millheiser L, Kingsberg S, Pauls R. A cross-sectional survey to assess the prevalence and symptoms associated with laxity of the vaginal
introitus. ICS Annual Meeting 2010. Abstract #206

Market for a Proven Solution

In  2009,  we  sponsored  several  on-line  marketing  surveys  in  the  U.S.  with  both  OB/GYNs  and  women,  ages  25-55,  to  assess

attitudes of physicians and women about vaginal laxity and towards a safe, non-invasive solution to treat this condition.

● Physician  Survey:  An  OB/GYN  marketing  survey  was  conducted  by  OB/GYN  Alliance  with  nearly  525  practicing
OB/GYNs  from  across  the  U.S.  The  objectives  of  the  study  were  to:  obtain  insights  from  physicians  on  physical  changes
resulting  from  childbirth  and  the  corresponding  sexual  health  implications  for  patients;  understand  the  perceptions  and
opinions of OB/GYN physicians on a procedure that could be offered to address vaginal laxity following childbirth; and gain
an understanding of whom the early adopters may be of the Geneveve treatment.

● Consumer Survey:  In  a  consumer  marketing  survey  conducted  by  Q&A  Research,  421  women  were  screened  for  vaginal
delivery,  age  (25-55),  income,  education  and  other  factors.  The  objectives  of  the  survey  were  to  assess  the  need  for  the
Geneveve  treatment  and  better  understand  the  complexity  of  emotions  and  the  psychological  profile  of  women  who
experience, but do not discuss, vaginal changes post childbirth.

Results  from  these  surveys  suggested  that  vaginal  laxity  is  a  significant unmet  medical  need,  and  that  patients  and  physicians
would  benefit  significantly  from  a  safe  and  effective  non-invasive  treatment  that  would  also  increase  physical  sensation  and  sexual
satisfaction following vaginal childbirth. Of the 421 patient respondents, up to 48% felt that vaginal laxity was a concern post-childbirth.
Furthermore, it is evident that patients and their OB/GYNs are not discussing vaginal laxity on a regular basis; in fact, we believe such
conversations occur quite infrequently due to many factors, including patient embarrassment and fear of being ridiculed, lack of time and
lack of solutions for physicians. Of the nearly 525 OB/GYNs surveyed, 84% indicated that vaginal laxity is the number one post-delivery
physical change for women, being more prevalent than weight gain, urinary incontinence and stretch marks, and believe that it is under-
reported  by  their  patients. Additionally,  in  a  separate  international  survey  of  urogynecologists,  83%  of  the  563  respondents  described
vaginal laxity as underreported by their patients and the majority considered it a bothersome condition that impacts sexual function and
relationships. Despite the lack of communication regarding this issue, we believe there is a strong interest among patients and doctors for a
treatment that is clinically proven and safe.

Applying U.S. census data, CDC Vital Statistics data and our projections from these studies, we estimate there are approximately
9 million post-partum women who are potential candidates for this procedure in the U.S. alone, approximately 4.5 million of whom could
be early adopters of Geneveve for vaginal laxity or sexual function.

In 2012, we conducted a similar consumer study in Japan and Canada in order to understand cultural differences that may exist
towards  vaginal  laxity  and  the  Geneveve  treatment.  The  results  corroborated  our  U.S.  survey  conclusions.  Applying  World  Health
Organization census data as well as data from individual countries, we estimate there are 25-30 million women outside the U.S. that could
be early adopters of the Geneveve treatment for vaginal laxity or sexual function.

In January 2018, we sponsored a survey of 1,500 women in Great Britain having had a vaginal delivery, and nearly half (48%)
worried before having a child about physical changes in their body from childbirth affecting their sex life; this increased to 67% of women
in the age range of 25-34. Approximately 4 in 10 (38% overall, 44% ages 25-34) have experienced vaginal tissue changes impacting their
physical sensation during sex, with the most common impacts consisting of feeling less confident overall, feeling embarrassed and self-
conscious, and feeling less enjoyment or intimacy with their partner.

6

 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
Current Treatments and Their Limitations

Currently, few clinically proven medical treatments are available to effectively treat vaginal laxity. The most widely prescribed

treatments include Kegel exercises and invasive surgical procedures, known as laser vaginal rejuvenation (“LVR”) or vaginoplasty.

● Kegel Exercises: Kegels are an exercise that was developed by Dr. Arnold Kegel designed to strengthen the muscles of the
pelvic  floor  -  the  pubococcygeal  (“PC”)  muscles  -  to  increase  vaginal  muscle  tone,  improve  sexual  response,  and  limit
involuntary  urine  release  due  to  stress  urinary  incontinence.  These  exercises  are  often  prescribed  following  childbirth  or
during and after menopause. However, we are not aware of any validated evidence indicating that Kegels improve vaginal
laxity or sexual function due to laxity.

● Surgical Procedures: Of the various alternatives for treating vaginal laxity, invasive surgical procedures, such as LVR, are
the only modalities with any proven efficacy outcomes. Typically, they are performed by plastic surgeons with patients under
general anesthesia. According to The International Society of Aesthetic Plastic Surgeons (“ISAPS”), approximately 114,135
LVR  surgeries  were  performed  world-wide  in  2013.  However,  these  invasive  surgical  procedures  are  expensive,  costing
thousands  of  dollars,  and  can  involve  weeks  of  post-surgical  recovery  time  for  the  patient.  They  also  carry  the  risk  of
scarring, which can lead to uncomfortable or painful intercourse, long-term or permanent loss of sensation, serious infection,
tissue necrosis, hematomas (fluid collection under the tissue that may require removal), and adverse reactions to anesthesia.

The Viveve Solution

We believe that  the Viveve System provides a compelling, clinically proven, safe, non-invasive treatment for vaginal laxity and
improvement of sexual function. Geneveve is conducted on an outpatient basis in a physician’s office. The procedure typically takes less
than  30  minutes  and  does  not  require  any  form  of  anesthesia.  To  perform  the  procedure,  a  physician  or  nurse  attaches  the  single-use
treatment tip to the handpiece. As described above, the return pad is then adhered to the patient’s upper leg to allow a path of travel for the
RF  current  back  to  the  generator.  Prior  to  treatment,  the  treatment  area  is  bathed  in  coupling  fluid,  which  is  used  for  conduction  and
lubrication. The area from the 1:00 o’clock position to the 11:00 o’clock position just inside the hymenal ring is treated using the Viveve
treatment tip by delivering a three-phased pulse: Phase 1 – cooling, Phase 2 – 90 Joules/cm2 of RF energy, and Phase 3 – cooling. Each
pulse lasts approximately eight seconds. The Viveve treatment tip is then repositioned in an overlapping fashion clockwise and the three-
phased treatment pulse is repeated. The entire circumferential treatment area from the 1:00 o’clock position to the 11:00 o’clock position is
treated five times with overlapping pulses. Treatment of the urethral area is avoided. During the treatment procedure patients are expected
to feel a sensation of warmth when the RF phase is delivered and a cooling sensation when the cooling phases are delivered. Based on our
current clinical results, Geneveve is only required once, with efficacy lasting for at least 12 months.

Benefits of the Geneveve Treatment

The Geneveve treatment provides a number of benefits for physicians and patients:

● Minimally-Invasive, Non-Ablative Alternative to Surgery with No Identified Safety Issues. Geneveve has been used to treat
over 200 clinical study patients and physicians have treated more than 7,000 patients with Geneveve as of the date of this
report. The procedure is non-invasive and offers an alternative to surgery at a much lower price with little or no downtime
from the patient’s normal routine. It is also not a surgical procedure and does not damage either the mucosal or sub-mucosal
tissue or require any form of anesthesia.

7

 
 
 
 
 
 
 
 
 
 
 
 
 
 
● Single Treatment. Geneveve is normally performed in a medical office setting as a single treatment that takes less than 30
minutes to complete. Our studies have shown that the clinical effect from our procedure occurs within one to three months
and patients continue to report improvements over a period of six months following treatment. In addition, our studies have
shown that Geneveve maintains its effect for at least 12 months, based upon currently available data from our clinical studies.

● Compelling Physician Economics. We believe that in an era of declining government and insurance reimbursement, many
physicians are seeking to add effective and safe, self-pay procedures to their practices. Geneveve can be easily adapted into
many physician practices and offers compelling per-procedure economics for the physician, despite requiring a small capital
equipment purchase.

● Ease of Use. The Viveve System offers an easy-to-use, straightforward user interface that allows a trained physician or nurse
((where permitted by law) to perform the treatment in less than 30 minutes. It provides real-time feedback and the patient can
be monitored during the treatment. The handpiece and single-use treatment tip are designed with a small profile for accurate
placement during treatment, comfort and ease of use.

Business Strategy

Our goal is to become the leading provider of non-invasive solutions to treat certain vaginal conditions by:

Broadening  the  conditions  we  treat  through robust  clinical  trials  and regulatory  label  expansion.  In  additional  to  pursuing
clearance/approval in the U.S. for the improvement of sexual function, we intend to conduct several clinical trials, and if successful,
submit for regulatory clearance/approval in the U.S. and abroad for mild-to-moderate stress urinary incontinence and potentially
vulvovaginal atrophy.

Increasing the Installed Base of the Viveve System. In our existing markets, we plan to expand the number of Viveve System users
by leveraging our current and future clinical study results and through innovative marketing programs directed at both physicians
and patients, where permitted by law. As a condition that has historically had no viable, non-invasive solutions, we intend to focus
much of our marketing effort on physician and patient education. Further, we intend to expand the number of regulatory approvals
both  internationally  and  in  the  U.S.,  to  further  increase  the  areas  in  which  we  can  market  the  Viveve  System  and  the  Geneveve
procedure.

Driving  Increased  Treatment  Tip  Usage .  Unlike  the  capital  equipment  model  of  other  businesses,  we  maintain  an  active,
continuous  relationship  with  our  physician  customer  base  because  of  the  single-use,  disposable  nature  of  the  treatment  tips.  We
work  collaboratively  with  our  physician  customer  base  to  increase  treatment  tip  usage  by  enhancing  customer  awareness  and
facilitating  the  marketing  efforts  of  our  physician  customers  to  their  patients  where  permitted  by  law.  We  believe  that  our
customers’ interests are closely aligned with our interests, and we plan to monitor the market to foster continued procedure growth
for our customers and treatment tip sales for us. We intend to launch innovative marketing programs with physician customers to
develop  a  profitable  Geneveve  practice.  In  addition,  we  plan  to  incorporate  practice  development  managers  into  our  sales
organization to support our physician customers.

Broadening Our Physician Customer Base. While our initial focus is on marketing our procedure to the aesthetics and OB/GYN
specialty, we intend to selectively expand our sales efforts into other physician specialties, such as urology, urogynecology, general
surgery and family practice. Additionally, we intend to pursue sales from physician-directed medi-spas with track records of safe
and successful aesthetic treatments.

Developing New Treatment Tips and System Enhancements. We intend to continue to expand our line of treatment tips to allow for
even shorter procedure times to benefit both physicians and patients. We also plan to pursue potential system modifications and
next generation enhancements that will further increase the ease-of-use of the Viveve System.

8

 
 
 
  
 
 
 
  
 
 
 
 
  
 
 
Investing  in  Intellectual  Property  and  Patent  Protection.  We  will  continue  to  defend  and  invest  in  expanding  our  intellectual
property portfolio, and we intend to file for additional patents to strengthen our intellectual property rights. Areas in which we may
pursue additional patent protection include, but are not limited to, redesign of certain system components, disposable components
and software algorithms. We believe that our intellectual property rights protect our position as the exclusive provider of a vaginal
laxity  treatment  using  monopolar  RF  technology  in  the  U.S.  and  in  many  other  countries.  (See  discussion  under  the  heading
“Patents and Proprietary Technology ”.) 

Our Customers

To  date,  we  have  focused  our  commercial  efforts  in  markets  where  we  have  received  regulatory  clearances/approvals.  Within
each  market,  we  target  thought  leaders  in  the  OB/GYN  and specialties  in  order  to  increase  awareness  of  vaginal  laxity  and  accelerate
patient  acceptance  of  Geneveve.  As  our  markets  mature,  we  intend  to  target  a  broader  number  of  physician  specialties,  including
urogynecologists, urologists, general surgeons, and family practitioners.

Through our sales employees, and distributors, we currently target physicians who have a demonstrated commitment to building a
high-volume, non-invasive, treatment business within their practice. As distribution of our product continues to expand globally, we intend
to continue to utilize distribution partners in most countries except the U.S. and Canada where we have a direct sales force.

Sales and Marketing

International

We currently market the Geneveve treatment and sell the Viveve System, including the single-use treatment tips, in 68 countries
outside the U.S. through trained sales employees and distributors. As of the date of this report, we had three sales directors (Europe and
Middle East, Asia Pacific, and Latin America), and a large network of distribution partners covering 67 countries throughout the world.

By  using  a  consultative  sales  process,  we  form  strong  relationships  with  our  customers  through  frequent  interactions.  Beyond
performing initial system installation and on-site training, which can occur within two weeks of a physician’s purchase decision, our sales
consultants provide ongoing consultation to physicians on how to integrate Geneveve into their practices and market procedures to their
patients, to the extent permitted by law.

We, or our distribution partner, also provide comprehensive training and education to each physician upon delivery of the Viveve

System. We require this initial training to assist physicians in safely and effectively performing the Geneveve treatment.

Our strategy to grow sales internationally is to:

● increase  penetration  of  the  Viveve  System  by  targeting  physicians  and  clinics  that  perform  in-office  procedures  and  by
implementing  direct-to-consumer  marketing  programs,  where  permitted  by  law,  to  increase  patient  awareness  often  in
collaboration with our distribution partners;

● expand into new international markets by gaining regulatory approval, and identifying and training qualified distributors; and

● expand  the  scope  of  physicians  who  offer  Geneveve  in  addition  to  OB/GYNs,  including  plastic  surgeons,  dermatologists,

general surgeons, urologists, urogynecologists and primary care physicians.

9

 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
Further,  we  intend  to  actively  engage  in  promotional  opportunities  through  participation  in  industry  tradeshows,  clinical
workshops and company sponsored conferences with expert panelists, as well as through trade journals, brochures, and our website. We
intend  to  also  actively  engage  in  direct-to-consumer  marketing  of  Geneveve  where  permitted  by  law,  including  extensive  use  of  social
media, in many cases on a cooperative basis with our distribution partners.

United States

In December 2008, we received regulatory clearance from the FDA for a previous version of the device, no longer manufactured,
for use in general surgical procedures for electrocoagulation and hemostasis. In March 2015, we submitted a Special 510(k) to the FDA
seeking clearance for the updated Viveve System to take into account the design modifications to the original 510(k) cleared device, which
include improved user interface capabilities and enhanced manufacturability. In October 2016, we received clearance from the FDA to sell
the  updated  device  for  use  in  general  surgical  procedures  for  electrocoagulation  and  hemostasis,  and  in  January  2017  we  hired  our
inaugural sales team.

We are actively seeking regulatory clearance from the FDA to allow us to begin to market the Viveve System for the treatment of
vaginal tissue to improve sexual function, to physicians practicing in the U.S. and to build awareness of Geneveve among patients residing
in  the  U.S.  In  2017  Viveve  worked  through  multiple  rounds  of  questions  and  held  several  meetings  with  the  Agency  regarding  the
proposed protocol and other aspects of the clinical study design. In response to the FDA’s last request, a tissue temperature time history
study  was  successfully  completed,  and  the  results  submitted  to  the Agency.  If  the  FDA  accepts  the  in  vivo  results,  has  no  additional
questions and approves the IDE, we intend to begin our U.S. clinical study to demonstrate the safety and effectiveness of the device to treat
vaginal laxity and/or improve sexual function.

Clinical Studies  

We have completed several pre-clinical  and human clinical studies in vaginal tissue. We are currently preparing to conduct two
additional clinical studies within the U.S., if and when we receive approval of our IDE applications from the FDA. While we believe that
the previously conducted pre-clinical and human clinical studies have shown that the Viveve System and its Geneveve treatment have a
very strong safety profile and is highly effective, there is risk that the FDA will not agree with this assessment.

Pre-clinical Studies

In 2010, in collaboration with West Virginia University, we conducted an animal study in sheep to assess the safety, and further
understand the mechanism of action, of Geneveve. The vaginal introitus of five parous sheep were treated once with the Viveve System
using  a  variety  of  energy  levels  (75−90  Joules/cm2).  Each  sheep  then  underwent  serial  vaginal  biopsies  immediately  after  treatment,  at
approximately one week, and at one, three and six months (4-5 samples per occurrence). Control biopsies were also obtained from three
untreated  parous  sheep.  We  examined  the  vaginal  mucosa  and  underlying  connective  tissue  for  thermal  changes  and  subsequent  tissue
responses  over  a  six-month  period  through  light  microscopic  examination  of  haematoxylin  and  eosin  (“H&E”)  stained  slides  that  were
reviewed by pathologists who were blinded as to the treated and untreated sheep.

The  results  of  the  study  indicated  that  the  optimal  level  of  RF  energy  delivered  was  90  J/cm2  and  the  biopsies  supported  the
hypothesis  that  the  mechanism  of  action  of  our  technology  involves  connective  tissue  remodeling  with  fibroblast  activation  and  new
collagen  production.  Given  the  post-treatment  absence  of  ulcerations,  regional  necrosis  or  diffuse  fibrosis,  throughout  the  six-month
follow-up period, we believe that FDA will eventually agree with our assessment regarding the safety profile of the Viveve System.

As  part  of  our  clinical  studies,  we  have  studied  and  continue  to  study,  the  interaction  of  RF  energy  and  tissue  to  further
understand the mechanism of action of the Geneveve procedure. We have used transmission electron microscopy on ovine biopsied tissue
samples  to  corroborate  that  our  product  induces  subtle  collagen  modification  and  the  deposition  of  new  collagen  that  leads  to  tissue
tightening and restoration of tissue elasticity. We have developed histology techniques to investigate the depth of heat in tissue, fibroblast
activation and collagen deposition that we believe is responsible for long-term improvement and tightening of tissue. We have also created
three-dimensional  computer  models  to  study  tissue  heating  with  our  product.  Determining  the  effectiveness  of  this  type  of  treatment  is
inherently a subjective evaluation. When performing our clinical studies, we attempt to utilize the most compelling measures we can in
order to provide convincing evidence of efficacy.

10

 
 
 
 
  
 
 
 
 
 
  
 
Clinical Studies – Vaginal Laxity and Sexual Function

United States Pilot Study

We  conducted  our  first  human  study  beginning  in  November  2008.  The  study  was  a  single-arm  study  (without  a  control
group) conducted in 24 female subjects, ages 25-44 years old, each of whom had experienced at least one full-term vaginal delivery. The
study was designed to assess the safety and efficacy of the procedure at three RF dosing levels. Each woman underwent a single Geneveve
treatment, with no anesthesia – three patients received 60 joules/cm2, three patients received 75 joules/cm2, and 18 patients received 90
joules/cm2.  Patient  outcomes  were  measured  at  baseline,  one  month,  three  months,  six  months,  and  12  months  using  several  validated
patient-reported  outcome  measures,  including  a  company-designed  vaginal  laxity/tightness  questionnaire  (“VSQ”),  Female  Sexual
Function Index (“FSFI”), Female Sexual Distress Scale-Revised (“FSDS-R”) and the Global Response Assessment.

Within one month after the Geneveve treatment, patients reported a statistically significant improvement in vaginal laxity scores,
sexual function and sexual satisfaction scores to pre-childbirth levels. These results continued throughout the 12-month follow-up period.
Additionally, patients reported a statistically significant decrease at one month, and thereafter, in their personal distress scores from sexual
activity. 

The Geneveve  treatment  also  demonstrated  a  strong  safety  profile  throughout  the  study.  The  treatment  was  well  tolerated  and
there  were  no  procedure-related  adverse  events  or  serious  adverse  events  through  the  12-month  follow-up  period.  Notwithstanding  the
safety in trials to date of the Viveve System, patients may experience undesirable side effects such as temporary swelling or reddening of
the treated tissue.

Japan Pilot Study

Our second human clinical study began in March 2010. This study was an open-label study conducted in 30 female subjects, ages
21-55 years old, each of whom had experienced at least one full-term vaginal delivery. The study was designed to assess the safety and
efficacy of the procedure. Each woman was treated once with the Viveve System, with no anesthesia, using 90 joules/cm2 of RF energy as
the therapeutic dose.

Patient  reported  outcomes  were  measured  at  baseline,  one  month,  three  months,  six  months,  and  12  months  using  several

validated patient-reported outcome measures, including VSQ, FSFI, FSDS-R and the Global Response Assessment.

Within one month after the Geneveve procedure, patients reported a statistically significant improvement in vaginal laxity scores,
sexual function and sexual satisfaction scores to pre-childbirth levels. These results continued throughout the 12-month follow-up period.
Additionally, patients reported a statistically significant decrease at one month, and thereafter, in their personal distress scores from sexual
activity.

The Geneveve procedure continued to demonstrate a strong safety profile. The treatment was well  tolerated  and  there  were  no

procedure-related adverse events or serious adverse events through the 12-month follow-up period.

VIVEVE I Clinical Study

In  the  fourth  quarter  of  2014,  we  began  the  VIVEVE  I  clinical  study  (VIveve treatment  of  the  Vaginal  Introitus  to  EValuate
Effectiveness), sometimes referred to in this report as the “OUS Clinical Trial,” a randomized, blinded and sham-controlled trial designed
to further demonstrate the efficacy and safety of Geneveve treatment versus a sham-control procedure for the treatment of vaginal laxity.
The  study  was  designed  to  demonstrate  that  Geneveve  was  superior  to  the  sham  treatment  for  the  primary  effectiveness  and  safety
endpoints described below. Nine clinical sites in four countries (Canada, Italy, Spain and Japan) enrolled 174 patients, which included pre-
menopausal females 18 years of age or older who experienced at least one full term vaginal delivery at least 12 months prior to enrollment
date,  randomized  in  a  2:1  ratio  to  either  an  active  treatment  group  or  sham-control  group.  Patients  were  followed  for  six  months  post-
treatment  to  assess  the  primary  effectiveness  and  safety  endpoints  of  the  study  with  data  being  collected  at  one,  three  and  six-month
intervals. The study also included a prospective interim data analysis at the three-month endpoint of 50% of the patients enrolled. Patients
randomized  to  the  sham  arm  were  offered  the  opportunity  to  receive  a  Geneveve  treatment  once  they  had  completed  the  six-month
evaluation following the sham intervention.

11

 
 
    
 
 
 
  
 
  
 
   
 
 
  
The primary endpoint of the study was the proportion of subjects in the active arm as compared to the proportion of  subjects in
the sham arm reporting no vaginal laxity at six months post-intervention. “No vaginal laxity” is operationally defined as a score > 4 on the
VSQ, a patient reported global assessment of vaginal laxity based on a 7-point scale. Additionally, the primary safety endpoint was the
proportion of subjects in the active arm experiencing an adverse event (“AE”) by six months post-treatment as compared to the proportion
of the subjects in the sham arm experiencing an AE by six months post-intervention. Secondary endpoints included the adjusted change in
mean score on the FSFI, FSDS-R and the Vaginal Laxity Inventory (“VALI”). The VALI was created specifically for the assessment of
vaginal  laxity  by  external  medical  experts.  Its  use  as  a  comprehensive  patient  reported  outcome  questionnaire  is  currently  being
scientifically validated by us to assess women’s vaginal laxity on a 7-point scale.

In April 2016, we completed the VIVEVE I study and reported the following results:

At six months (n=155), the proportion of patients reporting “no vaginal laxity” in the active arm, as measured by the VSQ, was
41.7%, while the proportion of patients reporting “no vaginal laxity” in the sham arm on the VSQ was 19.2% (p=0.005). Moreover, the
likelihood of having “no vaginal laxity” following treatment in the active arm was more than three times greater than for the sham arm
(p=0.006). Further, nearly 80% of the subjects in the active arm experienced a positive change in VSQ score versus baseline.

At six  months,  for  those  patients  who  scored  less  than  a  26.5  total  score  on  the  FSFI  at  baseline  (n=103),  the  adjusted  mean
change from baseline score between the active arm and the sham arm was 3.2 (p=0.009). Moreover, for each of the six individual domains
of the FSFI, subjects in the active group reported a greater increase in score than in the sham group. Change in scores from baseline for
both the sexual arousal and orgasm domains were Statistically Significant and nearly 93% of subjects in the active arm experienced an
increase in score versus baseline.

At six months, FSDS-R and VALI were also assessed as part of the secondary end-point analysis. While subjects in the active

arm reported a greater increase in scores than the sham arm, the results for the FSDS-R and VALI were not Statistically Significant.

Safety for the study was assessed on the entire study population (n =174). Subjects reported the same level of unrelated (32.5%
active versus 35.1% sham), related (11.1% active versus 12.3% sham) and serious (0.0% active versus 1.8% sham) adverse events in both
the active and sham arm, further demonstrating that the Geneveve treatment is well tolerated with no safety concerns.

We  believe  that  the  consistency  of  results  across  these  three  clinical  study  populations,  is  indicative  of  the  cross-cultural
similarities  in  this  medical  condition  and  the  positive  impact  that  an  effective  non-invasive  treatment  can  have  on  the  sexual  health  of
women after vaginal childbirth.

Clinical Studies – Mild-to-Moderate Stress Urinary Incontinence

Stress  urinary  incontinence (SUI)  is  a  medical  condition  affecting  an  estimated  25-30  million  women  worldwide.  It  is  a  major
challenge  for  women,  particularly  those  who  have  experienced  childbirth.  Upwards  of  55%  of  women  with  a  previous  vaginal  delivery
may  exhibit  symptoms  of  SUI.  The  need  to  use  an  external  pad  to  absorb  urine  leakage  associated  with  even  normal  activities  such  as
coughing  or  laughing  is  unsatisfactory,  inconvenient,  often  embarrassing  and  negatively  impacts  a  woman’s  quality  of  life.  Currently
available and effective treatment options are extremely limited. Pelvic floor exercises (Kegels) and muscle strengthening products offer
some benefit, but compliance and sustained benefit can be an issue. More aggressive approaches to manage SUI include pelvic surgery,
slings and mesh. These options involve risk and recovery time and are a last resort for many patients. We believe that the ability to offer a
minimally invasive, safe and effective treatment option for SUI using our CMRF technology would address an enormous unmet healthcare
need for women.

12

 
 
 
 
 
 
 
 
 
 
 
In 2017, Viveve funded a single-arm investigator sponsored study to assess the effects of our CMRF technology in treating patients
with  mild-to-moderate  SUI.  The  study  was  conducted  in  Calgary, Alberta  and  included  10  patients  who  underwent  treatment  with  our
CMRF technology under a proprietary treatment protocol. Patients were followed for 12 months with safety and clinical results reported at
4, 6, 9 and 12 months post-treatment. Clinical results included composite scores from the validated ICIQ-UI-SF (International Consultation
on  Incontinence  Questionnaire–Urinary  Incontinence-Short  Form)  and  UDI-6  (Urogenital  Distress  Inventory-Short  Form)  outcome
questionnaires. Results at 12 months (n=9) included an 89% responder rate (percentage of patients showing an improvement from baseline)
for the ICIQ-UI-SF and a 100% responder rate on the UDI-6. Additionally, patients showed a 40% mean improvement on the ICIQ-UI-SF
and a 51% mean improvement on the UDI-6 at 12 months across both validated endpoints. No device-related safety issues were reported
in any of the patients.

As a result, we intend to conduct two additional registration trials in Canada and the United States:

International Registration Study Overview - LIBERATE (International). LIBERATE (International) is intended to be a randomized,
double-blind,  sham-controlled  study  conducted  in  up  to  10  sites  in  Canada  and  including  up  to  100  patients  suffering  from  mild-to-
moderate SUI. The primary efficacy endpoint is expected to be the 6-month change from baseline in the one-hour pad weight test and will
include 12 months of safety follow-up, as well as assessments in other secondary endpoints. The Company is currently in the process of
reviewing  the  protocol  with  Health  Canada,  and  if  the  results  of  the  study  are  positive,  expects  to  use  the  outcome  of  this  study  for  a
registration filing in Canada and for CE Mark application in the EU for the temporary improvement of mild-to-moderate SUI symptoms.

U.S.  Registration  Study  Overview  -  LIBERATE  (U.S.).  LIBERATE  (U.S.)  is  intended  to  be  a  randomized,  double-blind,  sham-
controlled study in up to 25 centers across the U.S. and including up to 200 patients suffering from mild-to-moderate SUI. The primary
efficacy  endpoint  is  expected  to  be  the  12-month  change  from  baseline  in  the  one-hour  pad  weight  test  and  will  include  12  months  of
safety follow-up, as well as assessments in other secondary endpoints. The Company anticipates submitting an IDE to the FDA for the
temporary improvement of mild-to-moderate SUI symptoms.

The FDA must approve  the Company’s IDE application before the Company may begin conducting the LIBERATE (U.S.) study.
There can be no assurance that the FDA will approve our IDE application, or that the FDA may not require that the protocols be changed
or  that  additional  pre-clinical  work  be  conducted  prior  to  approving  the  IDE.  Similarly,  the  Company  must  submit  an  application  for
Investigational  Testing  Authorization  to  Health  Canada,  and  Health  Canada  must  issue  an  authorization  to  conduct  the  proposed
investigational testing before the Company may begin the LIBERATE (International) study. Again, there can be no assurance that Health
Canada will approve our application for Investigational Testing Authorization, or that Health Canada may not require that the protocols be
changed or that additional pre-clinical work be conducted prior to approving the application for Investigational Testing Authorization.

Research and Development

We intend to focus on various research and development efforts, including but not limited to:

● conducting additional human clinical trials, in order to support marketing applications for additional indications in the U.S.

and internationally, including but not limited to SUI and vulvovaginal atrophy;

● implementing cost improvement programs to further increase gross margins and our gross profit opportunity;

● designing new treatment tips and system enhancements to further optimize ease-of-use and reduce procedure times for

patients and physicians; and

13

 
 
 
 
 
  
 
 
  
 
 
 
 
 
 
● continuing to enhance the security within the Viveve System to prevent counterfeiting and refurbishment.

We  have  formed  strategic  relationships  with  outside  contractors  for  assistance  on  research  and  development  projects,  and  we
work closely with experts in the medical community to supplement our research and development resources. Research and development
expenses for the years ended December 31, 2017 and 2016 were $12,343,000 and $8,365,000, respectively. In the future, we expect to
pursue further research and development initiatives to improve and extend our technological capabilities and to foster an environment of
innovation and quality.

Manufacturing

Our  manufacturing  strategy  involves  the  combined  utilization  of  internal  manufacturing  resources  and  expertise,  as  well  as
approved  suppliers  and  contract  manufacturers.  Our  internal  manufacturing  activities  include  the  testing  and  packaging  of  Viveve
treatment  tips  and  handpieces,  as  well  as  the  final  integration,  system  testing  and  packaging  of  the  Viveve  System.  We  outsource  the
manufacture  of  components,  subassemblies  and  certain  finished  products  that  are  produced  to  our  specifications  and  shipped  to  our
Englewood, Colorado facility for final assembly or inspection, testing and certification. Our finished products are stored at and distributed
from  our  Englewood,  Colorado  facility.  Quality  control,  risk  management,  efficiency  and  the  ability  to  respond  quickly  to  changing
requirements are the primary goals of our manufacturing operations.

We  have  arrangements  with  our  suppliers  that  allow  us  to  adjust  the  delivery  quantities  of  components,  subassemblies  and
finished products, as well as delivery schedules, to match our changing requirements. The forecasts we use are based on historical trends,
current  utilization  patterns  and  sales  forecasts  of  future  demand.  Lead  times  for  components,  subassemblies  and  finished  products  may
vary significantly depending on the size of the order, specific supplier requirements and current market demand for the components and
subassemblies. Most of our suppliers have no contractual obligations to supply us with, and we are not contractually obligated to purchase
from them, the components used in our devices.

We obtain programmable memory chips for our treatment tips and the coolant valve for the handpiece from single suppliers, for
which  we  attempt  to  mitigate  risks  through  inventory  management  and  utilization  of  12-  to  18-month  purchase  orders,  and  sterilization
services from a single vendor, for which we attempt to mitigate risks by using two sterilization chambers at each of two locations. Other
products and components come from single suppliers, but alternate suppliers have been qualified or, we believe, can be readily identified
and qualified. In addition, the availability of cryogen for our cooling module, which we can source from multiple suppliers, may fluctuate
due to changes in the global supply of this material. To date, shipments of finished products to our customers have not been delayed due to
material delays in obtaining any of our components, subassemblies or finished products.

We are required to manufacture our product in compliance with Title 21 of the Co de of Federal Regulations Part 820 (“21 CFR
820”)  enacted  by  the  FDA  (known  as  the  Quality  System  Regulation  or  QSR).  21  CFR  820  regulates  the  methods  and  documentation
relating  to  the  design,  testing,  control,  manufacturing,  labeling,  quality  assurance,  packaging,  storage  and  shipping  of  our  product.  We
maintain quality assurance and quality management certifications to enable us to market our product in the member states of the European
Union, the European Free Trade Association and countries which have entered into Mutual Recognition Agreements with the European
Union.  These  certifications  include  EN  ISO  9001:2000  and  CAN/CSA  ISO  13485:2003.  We  are  also  required  to  maintain  our  product
registration in a number of other foreign markets such as Canada.

We use small quantities of common cleaning products in our manufacturing operations, which are lawfully disposed of through a
routine  waste  management  program.  Except  for  costs  that  may  be  incurred  in  the  future  in  connection  with  environmental  regulations
requiring the phase out of R134a, a hydrofluorocarbon, or HFC, upon which our cooling module relies, we do not anticipate any material
costs due to compliance with environmental laws or regulations. In 2007, the European Union enacted directives aimed at the automotive
industry  for  the  removal  of  HFC's  from  air  conditioning. As  a  result  of  these  directives,  we  anticipate  that  similar  directives  may  be
imposed on the medical device industry over the next decade. While we do not anticipate that we will have to incur costs in the near future
to develop an alternative cooling module for our device which is not dependent on HFCs, if and when we are required to do so, and if we
do not do so in a timely or cost-effective manner, the Viveve System may not be in compliance with environmental regulations, which
could result in fines, civil penalties and the inability to sell our products in certain major international markets.

14

 
 
 
  
  
 
 
 
 
  
 
We  generally  offer a one-year warranty providing for the repair, rework or replacement (at the Company’s option) of products
that fail to perform within stated specifications. To the extent that any of our components have performance related or technical issues in
the  field,  we  typically  replace  those  components  as  necessary.  We  also  sell  a  small  number  of  extended  service  agreements  on  certain
products  for  the  period  subsequent  to  the  normal  one-year  warranty  provided  with  the  original  product  sale,  the  revenue  of  which  is
recognized over the service agreement period. Revenue from sale of such extended service agreements was immaterial for the years ended
December 31, 2017 and 2016.

Patents and Proprietary Technology

We rely on patent, copyright, trade secret and trademark laws and confidentiality agreements to protect our technology and the
Viveve  System.  We  have  an  exclusive  license  to  or  own  4  issued  U.S.  patents  directed  to  our  technology  and  the  Viveve  System.
Additionally, we have 8 pending U.S. patent applications, 56 issued foreign patents, and 23 pending foreign patent applications, some of
which foreign applications preserve an opportunity to pursue patent rights in multiple countries. 

US Patents

Foreign Patents

Issued
4

Pending
8

Issued
56

Pending
23

All of our employees and consultants are required to execute confidentiality agreements in connection with their employment and
consulting relationships with us. We also require them to agree to disclose and assign to us all inventions conceived or made in connection
with the employment or consulting relationship. We cannot provide any assurance that our employees and consultants will abide by the
confidentiality  or  invention  assignment  terms  of  their  agreements.  Despite  measures  taken  to  protect  our  intellectual  property,
unauthorized parties may copy aspects of our product or obtain and use information that we regard as proprietary.

“Viveve,” is a registered trademark in the U.S. and several foreign countries. Geneveve is a registered trademark in the European
Community, China, Taiwan and South Korea; there are pending applications in the U.S. as well as other foreign countries. As of the date
of this report, we have one registered trademark in  the  U.S.,  as  well  as  various  foreign  registrations  protecting  the  various  marks  in  20
countries outside of the U.S. We may file for additional trademarks to strengthen our trademark rights, but we cannot be certain that our
trademark applications will issue or that our trademarks will be enforceable.

Edward Knowlton Licensed Patents

On February 10, 2006, Viveve, Inc. entered into an Intellectual Property Assignment and  License Agreement  with  Edward  W.
Knowlton (“Knowlton”), as amended on May 22, 2006 and July 20, 2007 (collectively, the “Knowlton IP Agreement”), pursuant to which
Knowlton  granted  to  Viveve,  Inc.  an  exclusive,  royalty-free  and  perpetual  worldwide  sublicense  to  certain  intellectual  property  and
technology licensed to Knowlton from a third party, including rights to several patents and patent applications owned by Thermage, Inc.
outside  the  field  of  contraction,  remodeling  and  ablation  of  the  skin  through  and  including  (but  not  beyond)  the  subcutaneous  fat  layer
below  the  skin  (collectively,  the  “Knowlton  Licensed  IP”).  The  sublicense  under  the  Knowlton  Licensed  IP  is  fully-paid,  transferable,
sublicensable and permits us to make, have made, use, sell, offer for sale and import any product or technology solely for use in the field
of transmucosal treatment of the vagina or vulva (the “Field”) and to practice any process, method, or procedure solely in the Field. The
Knowlton IP Agreement also assigns to us all technology and related intellectual property rights owned by Knowlton for the development
and commercialization of devices, including any improvements, in the Field (the “Knowlton Assigned IP”). We are obligated to file and
reasonably prosecute any patent applications that include a description of the Knowlton Assigned IP as prior art and maintain all patents
included in the Knowlton Assigned IP, at our expense. In consideration of the sale, assignment, transfer, release and conveyance and other
obligations of Knowlton under the Knowlton IP Agreement, Viveve, Inc. issued 200,000 shares of our common stock to Knowlton and
agreed to engage the consulting services of Knowlton.

15

 
 
  
 
 
   
 
   
   
   
 
   
   
 
 
 
 
 
 
 
  
      Also on February 10, 2006, Viveve, Inc. entered into a Consulting Agreement with Knowlton (“Knowlton Consulting Agreement”),
pursuant  to  which  Knowlton  assigned  all  rights  to  any  inventions  and  intellectual  property  developed  during  the  course  of  providing
consulting services in the Field during the term of the agreement. Unless earlier terminated pursuant to the provisions described therein,
the term of the Knowlton Consulting Agreement continued until the earlier to occur of (i) the date that is six months after the closing of an
initial public offering of Viveve, Inc.’s stock; or (ii) the acquisition by a third party of all or substantially all of the business or assets of
Viveve, Inc., whether by asset or stock acquisition, merger, consolidation or otherwise. The agreement could be renewed only upon the
mutual written agreement of the parties prior to its expiration. The Knowlton Consulting Agreement expired by its terms on September 23,
2014. The assignment of the intellectual property developed during the term of the Knowlton Consulting Agreement survives termination.

Agreement with Solta Medical

Effective April  30,  2010,  Viv eve,  Inc.  entered  into  a  Supply Agreement  (the  “Supply Agreement”)  with  Solta  Medical,  Inc.
(“Solta”), pursuant to which Solta agreed to sell to Viveve, Inc. the cryogen cooling method and coupling fluid that Solta uses with its
ThermaCool®  System  (“TC3  System”)  for  use  with  our  compatible  radiofrequency  medical  device  for  the  purpose  of  conducting  our
initial clinical trials. The applicable term of the Supply Agreement is the later of the period through completion of our initial clinical trials
or six months following the effective date. On October 14, 2010, the parties amended the term of the Supply Agreement to remain in effect
for so long as Solta supports its TC3 System. In the event that Solta discontinues support of its TC3 System and terminates the Supply
Agreement, Solta agrees to (i) provide us with information for Solta’s cryogen supplier, (ii) permit us to make any arrangement with such
supplier for a continued supply of cryogen and (iii) grant us a royalty free, non-exclusive perpetual license under any Solta intellectual
property directed to the design of the cryogen container in the field of treating vaginal tissue.

The  portion  of  the  Supply Agreement  relating  to  coupling  fluid  was  subsequently  superseded  by  the  parties ’  Coupling  Fluid
License and Product Supply Agreement on September 30, 2010, pursuant to which Solta agreed to (i) grant to Viveve, Inc. a license for the
coupling  fluid  and  (ii)  supply  the  coupling  fluid  at  preferred  pricing  for  two  years  and  at  non-preferred  pricing  after  two  years.  The
agreement grants to us a royalty-free, fully paid-up, worldwide, perpetual, exclusive license in the field of treating vaginal tissue, with a
right  to  grant  sublicenses  in  such  field,  to  make,  have  made,  use  and  sell  coupling  fluid  for  an  aggregate  license  fee  of  $125,000.  The
agreement was for an initial term of three years, after which it continues to remain in effect unless and until terminated in accordance with
the terms therein. In addition, while the terms of the original agreement permit the use of the cryogen cooling method for initial clinical
trials, Viveve also purchases the cryogen cooling method and coupling fluid from Solta for commercial purposes.  We currently do not
have  an  alternative  source  of  cryogen  and  if  Solta  refuses  to  sell  to  us  for  commercial  reasons,  or  otherwise,  our  business  could  be
materially adversely affected.

Agreement with Stellartech Research Corporation

On  June  12,  2006,  Viveve,  Inc.  entered  into  the  Stellartech  Agreement,  as  amended  and  restated  on  October  4,  2007,  with
Stellartech for an initial term of three years in connection with the performance of development and manufacturing services by Stellartech
and the license of certain technology and intellectual property rights to each party. Under the Stellartech Agreement, we agreed to purchase
300 units of generators manufactured by Stellartech. As of December 31, 2017, the Company has purchased 543 units. In conjunction with
the Agreement, Stellartech purchased 37,500 shares of Viveve, Inc.’s common stock at $0.008. Under the Stellartech Agreement, we paid
Stellartech  $7,912,000  and  $6,485,000  for  goods  and  services  during  the  years  ended  December  31,  2017  and  2016,  respectively.  In
addition,  Stellartech  granted  to  us  a  non-exclusive,  nontransferable,  worldwide,  royalty-free  license  in  the  Field  (defined  above  in  the
discussions  titled  “Edward  Knowlton  Licensed  Patents”)  to  use  Stellartech’s  technology  incorporated  into  deliverables  or  products
developed, manufactured or sold by Stellartech to us pursuant to the Stellartech Agreement (the “Stellartech Products”) to use, sell, offer
for  sale,  import  and  distribute  the  Stellartech  Products  within  the  Field,  including  the  use  of  software  object  code  incorporated  into  the
Stellartech Products. The Stellartech technology consists of know-how applicable to the manufacturing and repair of the Viveve System,
including any other intellectual property which Stellartech developed or acquired separate and apart from the Stellartech Agreement and all
related  derivative  works.  In  addition,  once  we  purchase  a  minimum  commitment  of  300  units  of  the  RF  generator  component  (the
“Minimum Commitment”) and the Stellartech Agreement expires, Stellartech is to grant us a nonexclusive, nontransferable, worldwide,
royalty-free,  fully-paid  license  to  use  the  Stellartech  technology  incorporated  into  the  Stellartech  Products  to  make  and  have  made
Stellartech Products in the Field.

16

 
 
  
 
 
 
 
  
Stellartech also granted (i) an exclusive (even as to Stellartech), nontransferable, worldwide, royalty-free license within the Field
under those certain intellectual property rights licensed to Stellartech pursuant to a development and supply agreement between Stellartech
and Thermage, dated October 1, 1997 (the “Thermage Technology”), to use any elements of the Thermage Technology incorporated into
the Stellartech Products, solely for the use, sale, offer for sale, importation and distribution within the Field; (ii) upon our satisfaction of
the Minimum Commitment and the expiration of the Stellartech Agreement, an exclusive, nontransferable, worldwide, royalty-free, fully-
paid  license  within  the  Field  under  Stellartech’s  license  rights  in  the  Thermage  Technology  to  use  any  elements  of  the  Thermage
Technology  which  are  incorporated  into  the  Stellartech  Products  to  make  and  have  made  Stellartech  Products  in  the  Field;  and  (iii)  the
exclusive right within the Field to prosecute infringers of the portion of Stellartech’s Thermage Technology rights exclusively licensed to
us.  Our  license  rights  in  Thermage  Technology  also  include  the  use  of  software  object  code  for  Thermage  Technology  used  in  the
Stellartech Products. As of the date of this report, the Stellartech Agreement has expired by its terms, however, the parties still continue to
operate  under  the  terms  of  the  agreement.  In  addition,  we  have  met  the  Minimum  Commitment  requirement,  and  therefore  we  are
permitted  to  use  the  Stellartech  technology  with  any  other  manufacturer.  If  Stellartech  refuses  or  is  unable  to  meet  our  delivery
requirements for the Viveve System, our business could be materially adversely affected.

In  March  2012,  Viveve,  Inc.  entered  into  a  Quality  and  Regulatory Agreement  with  Stellartech,  pursuant  to  which  the  parties
clarified their respective quality and regulatory responsibilities under the Stellartech Agreement. The Quality and Regulatory Agreement
provides  that  we  will  serve  as  the  legal  manufacturer  for  all  Stellartech  Products  developed  and  sold  to  us  thereunder  and  that  we  are
obligated to maintain all relevant quality assurance and regulatory processes and requirements required by any regulatory authority and to
comply with the processes and requirements set forth in the schedule of responsibilities provided in the agreement.

Government Regulation

The Viveve System is a medical device subject to extensive and rigorous regulation by international regulatory bodies as well as
the FDA. These regulations govern the following activities that we perform, or that are performed on our behalf, to ensure that medical
products exported internationally or distributed domestically are safe and effective for their intended uses:

● product design, development and manufacture;

● product safety, testing, labeling and storage;

● record keeping procedures;

● product marketing, sales and distribution; and

● post-marketing surveillance, complaint handling, medical device reporting, reporting of deaths, serious injuries or device

malfunctions and repair or recall of products.

In  addition  to  the  regulatory  approvals  already  received  in  connection  with  the  sale  of the  Viveve  System  in  the  foreign
jurisdictions  described  below  and  the  approvals/clearances  being  sought  in  the  U.S.,  we  are  currently  seeking  regulatory  approval  or
clearance for the sale of our product in many other countries around the world.

17

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
  
International

Sales of our product outside the U.S. are subject to foreign regulatory requirements that vary w idely from country to country. In
addition, exports of medical devices from the U.S. are regulated by the FDA. Complying with international regulatory requirements can be
an expensive and time-consuming process and approval is not certain. The time required to obtain registrations or approvals, as required by
other  countries,  may  be  longer  than  that  required  for  FDA  clearance,  and  requirements  for  such  registrations  or  approvals  may
significantly differ from FDA requirements. We may be unable to obtain or maintain registrations or approvals in other countries. We may
also incur significant costs in attempting to obtain and in maintaining foreign regulatory approvals. If we experience delays in receiving
necessary registrations or approvals to market our product outside the U.S., or if we fail to receive those registrations or approvals, we may
be unable to market our product or enhancements in international markets effectively, or at all, which could have a material adverse effect
on our business and growth strategy.

An entity that seeks to export a medical device that is legally marketed in the U.S. (e.g., an FDA cleared Class II medical device)

may do so without prior FDA notification or approval.

Because the  Viveve  System  has  been  cleared  by  the  FDA  for  “use  in  general  surgical  procedures  for  electrocoagulation  and
hemostasis,”  Viveve  does  not  obtain  approval  from  the  FDA  prior  to  exporting  the  device  to  foreign  countries. Additionally,  products
exported  from  the  U.S.  and  those  with  certain  levels  of  U.S.  content  are  subject  to  the  U.S.  export  control  and  sanctions  laws  and
regulations, which may restrict proposed transactions to certain countries, end-users and end-uses. Certain products may be controlled for
export and reexport and may require licensing or other authorization from the U.S. government prior to engaging in the export or reexport
transaction.  Changes  to  these  regulations  may  impact  the  ability  to  pursue  potential  opportunities  to  export  and  reexport  the  products
overseas.

Moreover,  entities  legally  exporting  products  from  the  U.S.  are  often  asked  by  foreign  customers  or  foreign  governments  to
supply  an  export  certificate  issued  by  the  FDA  to  accompany  a  device.  An  export  certificate  is  a  document  prepared  by  the  FDA
containing information about a product’s regulatory or marketing status in the U.S. We have requested the issuance of export certificates
to allow exports into many countries around the world, and the FDA has issued those export certificates to us. Accordingly, we provide
export certificates to many of our foreign customers.

Currently, the Viveve System is cleared for marketing in 62 countries throughout the world under the following indications for

use:

  Indication for Use:

  Countries Cleared for Marketing

General surgical procedures for
electrocoagulation and hemostasis

  Treatment of vaginal laxity

Treatment of the vaginal introitus after vaginal
childbirth to improve sexual function

  Taiwan, Thailand and U.S.

European Union (31 countries), Bahrain, Iran, S. Korea, Kuwait,
Lebanon, Malta, Qatar, Turkey, Ukraine, S. Africa
Australia, Brazil, Canada, Chile, Columbia, Costa Rica,
Dominican Republic, Hong Kong, Japan, Malaysia, Mexico,
Panama, Philippines, Singapore, UAE, Uruguay, and Venezuela

  Vaginal rejuvenation
General surgical procedures for
electrocoagulation and hemostasis & treatment of
vaginal laxity

  China

  S. Korea

Number of
Countries

3

40

17

1

1

Outside  the  U.S.,  we  market  and  sell  through  an  extensive  network  of  distribution  partners.  In  the  U.S., the  Viveve  System  is
indicated for use in general surgical procedures for electrocoagulation and hemostasis and we market and sell primarily through a direct
sales force.

18

 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
United States

FDA’s Premarket Clearance and Approval Requirements

Unless an exemption applies, any medical device we wish to commercially distribute in the U.S. will require premarket clearance
from the FDA. The FDA classifies medical devices into one of three classes. The classification system is risk based, with devices deemed
to  pose  the  lowest  risk  being  Class  I,  and  devices  posing  the  most  risk  being  Class  III.  Most  Class  I  devices  are  exempt  from  the
requirement to obtain FDA premarket clearance or approval. For most Class II devices (and a small number of Class I devices), a company
must submit to the FDA a premarket notification (known as 510(k) submission) requesting clearance to commercially distribute the device.
Devices deemed by the FDA to pose the greatest risk, such as life-sustaining, life-supporting or implantable devices, or devices deemed
not  substantially  equivalent  to  a  previously  cleared  510(k)  device,  are  placed  in  Class  III,  requiring  FDA  premarket  approval  via  a
Premarket Approval (“PMA”) application. The FDA has issued regulations identifying the Class into which different types of devices fall
and identifying whether the device type is exempt from the 510(k) process or if a 510(k) is needed.

510(k) Clearance Pathway

When  a  510(k)  clearance  is  required,  we  must  submit  a  premarket  notification  to  the  FDA  demonstrating  that  our  device  is
substantially equivalent to a previously cleared and legally marketed device or a device that was in commercial distribution before May
28, 1976 for which the FDA has not yet called for the submission of PMAs (known as a predicate device). The FDA strives to make a
determination that the device is substantially equivalent (SE) (i.e., clear the device) or not substantially equivalent (NSE) within 90 days
of  submission  of  the  notification.  As  a  practical  matter,  clearance  often  takes  significantly  longer.  The  FDA  may  require  further
information, including clinical data, to make a determination regarding substantial equivalence. If the FDA determines that the device is
not substantially equivalent to a previously cleared device, the FDA will issue an NSE letter and place the device into Class III.

Any modification to a 510(k)-cleared device that would constitute a major change in its intended use, or any change that could
significantly affect the safety or effectiveness of the device, requires a new 510(k) clearance and may even, in some circumstances, require
a  PMA,  if  the  change  raises  complex  or  novel  scientific  issues  or  the  product  has  a  new  intended  use.  The  FDA  requires  every
manufacturer to make the determination regarding the need for a new 510(k) submission in the first instance, but the FDA may review any
manufacturer’s decision. If the FDA were to disagree with a manufacturer’s determination that changes did not require a new 510(k), the
FDA could require the manufacturer to cease marketing and distribution and/or recall the modified device until 510(k) clearance or PMA
approval is obtained and the manufacturer could be subject to significant regulatory fines or penalties.

In  December  2008,  a  predecessor  company  to  Viveve  received  510(k)  clearance  for  a  previous  version  of  the Viveve  System.
Since then, we have made design modifications to the original 510(k)-cleared device. In March 2015, we submitted a Special 510(k) to the
FDA seeking clearance for the updated Viveve System to take into account the design modifications to the original 510(k)-cleared device,
which  included  improved  user  interface  capabilities  and  enhanced  manufacturability.  In  October  2016,  we  received  clearance  from  the
FDA to sell the updated device for use in general surgical procedures for electrocoagulation and hemostasis.

De Novo Process

If FDA has not issued a regulation classifying a particular type of device as Class I, and if there is no known predicate for a device
(i.e.,  a  legally-marketed  device  that  is  not  subject  to  premarket  approval  with  comparable  indications  for  use  and  technological
characteristics),  the  device  is  automatically  Class  III,  regardless  of  the  risk  the  device  poses.  If  a  device  is  automatically/statutorily
classified  into  Class  III  in  this  manner,  a  company  can  petition  FDA  to  reclassify  the  category  of  devices  into  Class  II  or  Class  I  via  a
process known as “Evaluation of Automatic Class III Designation,” which is typically referred to as the “de novo process.” The direct de
novo process allows a company to request that a new product classification be established without the company first submitting a 510(k)
notification for the device. The reclassification petition should include a risk-benefit analysis demonstrating that, when subject to general
controls or general and special controls, the probable benefits to health from use of the device outweigh any probable injury or illness from
such  use.  The  submitter  also  must  describe  why  general  controls  or  general  and  special  controls  are  adequate  to  provide  reasonable
assurance  of  safety  and  effectiveness  and  for  proposed  Class  II  devices,  provide  proposed  special  controls.  If  a  product  is  classified  as
Class  II  through  the  direct  de  novo  review  process,  then  that  device  may  serve  as  a  predicate  device  for  subsequent  510(k)  premarket
notifications, including by competitors.

19

 
 
 
 
  
 
 
 
 
 
 
We intend to seek FDA authorization to market the Viveve System for the treatment of vaginal tissue to improve sexual function
by utilizing the direct de novo process. However, we cannot predict when or if approval of such a petition will be obtained. In addition, if
FDA fails to grant a de novo petition, we will be required to seek FDA premarket approval (via the more stringent PMA process). Delays
in  receipt  of  FDA  clearance  or  failure  to  receive  FDA  clearance  or  approval  for  this  expanded  indication  could  reduce  our  sales,
profitability and future growth prospects.

Clinical Trials

Clinical  trials  are  almost  always  required  to  support  an  FDA  de  novo  reclassification  and  are  sometimes  required  for  510(k)
clearance. With respect to the Viveve System, the FDA has asked us to conduct a clinical study under an IDE, to support a future product
submission  (e.g.,  a  510(k)  or  a  de  novo  petition).  In  the  U.S.,  clinical  trials  on  medical  devices  generally  require  submission  of  an
application for an IDE to the FDA if the device is a “significant risk” device. The IDE application must be supported by appropriate data,
such  as  animal  and  laboratory  testing  results,  showing  that  it  is  safe  to  test  the  device  in  humans  and  that  the  testing  protocol  is
scientifically sound. The IDE must be approved in advance by the FDA for a specific number of patients. Clinical trials for significant risk
devices may not begin until the IDE application is approved by both the FDA and the appropriate institutional review boards (“IRBs”) at
the  clinical  trial  sites.  Our  clinical  trials  must  be  conducted  under  the  oversight  of  an  IRB  at  the  relevant  clinical  trial  sites  and  in
accordance with FDA regulations, including, but not limited to, those relating to good clinical practices. We are also required to obtain the
patients’ informed consent, in compliance with both FDA requirements and state and federal privacy regulations. We, the FDA, or the IRB
at each site at which a clinical trial is being performed may suspend a clinical trial at any time for various reasons, including a belief that
the risks to study subjects outweigh the benefits. Even if a trial is completed, the results of clinical testing may not demonstrate the safety
and efficacy of the device, may be equivocal or may otherwise not be sufficient to obtain clearance or approval of the product. Similarly,
in Europe and other regions, clinical study protocols must be approved by the local ethics committee and in some cases, including studies
with high-risk devices, by the Ministry of Health in the applicable country.

In June 2012, we submitted a pre-IDE application and requested an in-person meeting with the FDA to solicit feedback in advance
of filing an IDE to conduct a clinical study of the Viveve System to support regulatory submission. In August 2012, we met with the FDA
and received feedback on our pre-clinical data, historical clinical data, and a clinical protocol for a prospective randomized controlled trial.
We  had  a  second  meeting  with  the  FDA  on  December  17,  2015  and  received  additional  feedback  on  our  clinical  protocol  design  and
indication for use. In September 2016 we submitted an IDE application to FDA to begin a U.S. clinical study and the FDA has responded
with additional questions regarding the proposed protocol and other aspects of the clinical study design, which we are working to address.
If and when approval is received, we intend to begin our U.S. clinical study to demonstrate the safety and effectiveness of the device to
treat vaginal laxity and/or improve sexual function. 

Continuing Regulation

After a device is placed on the market, numerous regulatory requirements continue to apply. These include:

● product listing and establishment registration, which helps facilitate FDA inspections and other regulatory action;

● submission of Unique Device Identifiers (“UDIs”) to the FDA;

20

 
 
  
 
 
 
 
 
 
 
 
 
● QSRs,  which  require  manufacturers,  including  third-party  manufacturers,  to  follow  stringent  design,  testing,  control,

documentation and other quality assurance procedures during all aspects of the manufacturing process;

● labeling regulations and FDA prohibitions against the promotion of products for uncleared, unapproved or “off-label” uses to

both physician and consumers;

● regulations governing our interactions with healthcare practitioners;

● U.S. export control and sanctions regulations associated with the export and reexport of the products;

● Medical Device Reporting (“MDR”), regulations, which require that a manufacturer report to the FDA if its device may have
caused or contributed to a death or serious injury or malfunctioned in a way that would likely cause or contribute to a death or
serious injury if the malfunction were to recur;

● post-market surveillance regulations, which apply when necessary to protect the public health or to provide additional safety

and effectiveness data for the device;

● regulations pertaining to voluntary recalls and notices of corrections or removals; and

● any other post-market requirements that FDA might impose as part of the device approval or clearance process.

The  FDA  has  broad  post-market  and  regulatory  enforcement  powers.  We  and  our  third-party  manufacturers  are  subject  to
announced  and  unannounced  inspections  by  the  FDA  and  state  equivalents  such  as  the  Food  and  Drug  Branch  of  the  California
Department  of  Health  Services  (“CDHS”),  to  determine  compliance  with  the  QSR  and  other  regulations.  In  the  past,  our  Sunnyvale,
California  facility  has  been  inspected,  and  observations  were  noted,  including  an April  2012  CDHS  inspection  that  cited  deficiencies
related to signature authority of inspection documentation, incomplete corrective action responses, and labeling indicating that our product
contained  no  latex  without  proper  objective  evidence.  The  FDA  and  CDHS  have  accepted  our  responses  to  these  observations,  and  we
believe that we and our third-party manufacturer are in substantial compliance with the QSR.

Failure to comply with applicable regulatory requirements can result in enforcement action by the FDA, which may include any

of the following actions:

● warning letters, untitled letters, fines, injunctions, consent decrees and civil penalties;

● repair, replacement, refunds, recall or seizure of our products;

● operating restrictions, partial suspension or total shutdown of production;

● refusing our requests for 510(k) clearance, de novo reclassification, or premarket approval of new products or new intended

uses;

● refusing to grant export certificates for our product;

● withdrawing 510(k) clearance or premarket approvals that are already granted; and

● criminal prosecution.

If any of these events were to occur, it could have a material adverse effect on our business.

We are also subject to a wide range of federal, state and local laws and regulations, including those related to the environment,
health  and  safety,  fraud  and  abuse,  land  use,  advertising,  and  quality  assurance.  We  believe  that  compliance  with  these  laws  and
regulations as currently in effect will not have a material adverse effect on our capital expenditures, earnings and competitive and financial
position.

21

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Competition

The medical device industry is characterized by intense competition and rapid innovation. While we believe that our solution to
treat  vaginal  laxity  is  unique  and  offers  a  more  effective  solution  from  that  which  is  on  the  market  currently,  we  also  believe  that  the
market for the treatment of vaginal laxity and women’s sexual function remains a tremendous, under-developed opportunity. Therefore,
competition is expected to increase, particularly as the market becomes more developed with further solutions. Aside from Kegel exercises
and invasive surgical procedures, such as LVR, there are many companies developing or that have developed energy-based technologies
for vaginal rejuvenation as well as others developing drug therapies and therapeutics for the treatment of various types of female sexual
dysfunction. Further, the overall size and attractiveness of the market may compel larger companies focused in the OB/GYN, aesthetic or
women’s health markets, and with much greater capital and other resources, to pursue development of or acquire technologies that may
address  these  areas.  Potential  competitors  include,  but  are  not  limited  to,  Cynosure  (acquired  by  Hologic),  Syneron  Medical,  Fotona,
Thermi Aesthetics  (acquired  by Almirall,  S.A.),  Cutera,  Inmode,  BTL  and  others,  some  of  whom  have  more  established  products  and
customer relationships than we have.

Employees

As of March 8, 2018, we had 103 full-time employees and we retain the services of several qualified consultants. We believe that
our future success will depend in part on our  continued  ability  to  attract,  hire  and  retain  qualified  personnel.  None  of  our  employees  is
represented by a labor union, and we believe that our employee relations are good.

Continuance into Delaware

On  July  22,  2015,  at  our  2015 Annual  and  Special  Meeting  of  Stockholders,  our  stockholders  approved  a  special  resolution
authorizing a continuance of the Company (the “Continuance”) into the State of Delaware under the Delaware General Corporation Law
(the  “DGCL”)  and  the  adoption  of  charter  documents  that  comply  with  the  DGCL  in  connection  therewith,  effective  as  of  a  date  to  be
determined by the Board, in its sole discretion, no more than 12 months from the date of the meeting. On May 9, 2016, the Company filed
the necessary Application for Authorization to Continue into Another Jurisdiction and Statutory Declaration with the Yukon registrar. On
May 10, 2016, the Company filed a Certificate of Conversion and Certificate of Incorporation with the Secretary of State of the State of
Delaware to move its domicile from the Yukon Territory to Delaware.

The Continuance did not involve any change in our business, properties, corporate headquarters or management. The officers of
the Company immediately prior to the Continuance continued to serve as our officers following the Continuance, and the current members
of  the  Board  of  Directors  continued  to  serve  as  the  members  of  the  Board  following  the  Continuance.  There  was  no  change  in  our
operations, assets, liabilities or obligations as a result of the Continuance. Other than the approval of our stockholders and the filings with
the Yukon Registrar of Corporations and the Secretary of State of Delaware, there were no federal or state regulatory requirements that we
were required to comply with or approvals that we were required to obtain in connection with the Continuance.

Upon the effectiveness of the Continuance, each outstanding share  of our common stock continued to be an outstanding share of
our  common  stock  as  incorporated  in  Delaware  and  each  outstanding  option,  right  or  warrant  to  acquire  shares  of  our  common  stock
continued to be an option, right or warrant to acquire an equal number of shares of common stock under the same terms and conditions.
Upon effectiveness of the Continuance, we were governed by the Certificate of Incorporation filed with the Secretary of State of Delaware
and by bylaws prepared in accordance with the DGCL, which were approved by our stockholders at the 2015 Annual and Special Meeting.
Following the Continuance, we were governed by the DGCL instead of the Yukon Business Corporation Act.

22

 
 
 
 
 
  
 
 
  
 
Item 1A. Risk Factors

Investing in our common stock involves a high degree of risk. Prospective investors should carefully consider the risks described
below, together with all of the other information included or referred to in this Annual Report on Form 10-K, before purchasing shares of
our  common  stock.  There  are  numerous  and  varied  risks  that  may  prevent  us  from  achieving  our  goals.  If  any  of  these  risks  actually
occurs, our business, financial condition or results of operations may be materially adversely affected. In such case, the trading price of
our common stock could decline and investors in our common stock could lose all or part of their investment.

Risks Related to Our Business

We are dependent upon the success of  the Viveve System , which has a limited commercial history. If the device fails to gain or loses
market acceptance, our business will suffer.

In  2012,  we  began  marketing the Viveve System (radiofrequency generator, handpiece and single-use treatment tips) and other
ancillary consumables, in Canada, Hong Kong and Japan, and we expect that these sales will account for substantially all of our revenue
for the foreseeable future. The Viveve System may not significantly penetrate current or new markets, including the U.S. and elsewhere. If
demand for the Viveve System and Geneveve treatment does not increase as we anticipate, or if demand declines, our business, financial
condition and results of operations will be harmed.

We  compete  against  companies  that  have  more  established  products,  longer  operating  histories  and  greater  resources,  which  may
prevent us from achieving significant market penetration or increased operating results.

The  medical  device  and  aesthetics  markets  are  highly  competitive  and  dynamic  and  are  marked  by  rapid  and  substantial
technological  development  and  product  innovations.  Demand  for the  Viveve  System  could  be  diminished  by  equivalent  or  superior
products and technologies developed by competitors. Specifically, Geneveve competes against other offerings in these markets, including
laser and other light-based medical devices, pharmaceutical and consumer products, surgical procedures and exercise therapies.

Competing  in  these  markets  could  result  in  price-cutting,  reduced  profit  margins  and  loss  of  market  share,  any  of  which
would  harm  our  business,  financial  condition  and  results  of  operations.  Our  ability  to  compete  effectively  depends  upon  our  ability  to
distinguish our company and Geneveve from our competitors and their products, on such factors as:

● safety and effectiveness;
● product pricing;
● success of our marketing initiatives;
● compelling clinical data;
● intellectual property protection;
● quality of customer support; and
● development of successful distribution channels, both domestically and internationally.

Some of our competitors have more established products and customer relationships than we have, which could inhibit our market
penetration  efforts.  For  example,  we  may  encounter  situations  where,  due  to  pre-existing  relationships,  potential  customers  decide  to
purchase additional products from our competitors.  Potential customers may need to recoup the cost of expensive products that they have
already purchased to perform LVR surgery or vaginoplasty and thus may decide not to purchase, or to delay the purchase of, the Viveve
System.  If  we  are  unable  to  achieve  continued  market  penetration,  we  will  be  unable  to  compete  effectively  and  our  business  will  be
harmed.

In addition, potential competitors could have significantly greater financial, research and development, manufacturing, and sales
and marketing resources than we have and could utilize their greater resources to acquire or develop new technologies or products that
could effectively compete with our existing product. Given the relatively few competitors currently in the market, any such action could
exacerbate existing competitive pressures, which could harm our business.

23

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
  
Performing clinical studies with the Viveve System ,  and  collecting  data  from, its Geneveve treatment is inherently subjective, and we
have  limited  data  regarding  the  efficacy  of  Geneveve.  If  future  data  is  not  positive  or  consistent  with  our  prior  experience,  rates  of
physician adoption will likely be harmed.

 We believe that in order to significantly grow our business, we will need to conduct future clinical studies of the effectiveness of
the Viveve System and its Geneveve treatment. Clinical studies of vaginal laxity and sexual function are subject to a number of limitations.
First, these studies do not involve objective standards for measuring the effectiveness of treatment. Subjective, patient reported outcomes
are the most common method of evaluating effectiveness. As a result, clinical studies may conclude that a treatment is effective even in the
absence of objective measures. Second, as with other non-invasive, energy-based treatments, the effect of the Geneveve treatment varies
from patient to patient and can be influenced by a number of factors, including the age, ethnicity and level of vaginal laxity and sexual
function of the patient, among other things.

 Current published studies of Viveve’s CMRF technology conducted in the U.S. and Japan have investigated the tissue-tightening
effect of its treatment using single-arm studies where all patients enrolled in the trial received the same treatment without comparison to a
control  group.  Clinical  studies  designed  in  a  randomized,  blinded  and  controlled  fashion  (e.g.,  assessing  the  efficacy  of  a  product  or
therapy  versus  a  placebo  or  sham  group)  represent  the  gold-standard  in  clinical  trial  design. A  sham-controlled  treatment  or  procedure
refers to a procedure performed as a control and that is similar to the treatment or procedure under investigation without the key therapeutic
element being investigated. Future clinical studies, which may be required to drive physician adoption or support regulatory clearance or
approval,  will  likely  require  randomized,  blinded  and  controlled  trial  designs.  In  the  fourth  quarter  of  2014,  we  initiated  a  randomized,
blinded and sham-controlled clinical trial in Europe and Canada designed to demonstrate the efficacy of the Geneveve procedure versus a
sham-controlled procedure for the treatment of vaginal laxity and sexual function (the “OUS Clinical Trial”). In April 2016, we completed
this study. (See discussion under the heading  “Clinical Studies”.)

Additionally,  we  have  not  conducted  any  head-to-head  clinical  studies  that  compare  results  from  treatment  with the  Viveve
System to surgery or treatment with other therapies. Without head-to-head studies against competing alternative treatments, which we have
no  current  plans  to  conduct,  potential  customers  may  not  find  clinical  studies  of  our  technology  sufficiently  compelling  to  purchase
Geneveve.  If  we  decide  to  pursue  additional  studies  in  the  future,  such  studies  could  be  expensive  and  time  consuming,  and  the  data
collected may not produce favorable or compelling results. If the results of such studies do not meet physicians’ expectations, Geneveve
may not become widely adopted, physicians may recommend alternative treatments for their patients, and our business may be harmed.

We  currently  have  clearance  to  market the  Viveve  System   in  the  U.S.  for  general  surgical  procedures  for  electrocoagulation  and
hemostasis but not for vaginal laxity or sexual function. If we want to sell our device and single-use treatment tips in the U.S. for the
treatment of vaginal laxity or sexual function, we will need to obtain additional FDA clearance or approval, which may not be granted.

 Developing and promoting our CMRF technology in additional countries for additional indications, including the U.S., is a key
element of our future growth strategy. We currently do not have FDA clearance or approval to market the Viveve System in the U.S. for
the treatment of vaginal laxity or sexual function. We intend to seek clearance or approval from the FDA to expand our marketing efforts
and  have  engaged  with  the  FDA  to  help  improve  our  likelihood  of  success.  However,  we  cannot  predict  whether  we  will  receive  such
clearances or approvals. The FDA will require us to conduct clinical trials to support regulatory clearance or approval, which trials may be
time-consuming and expensive, and may produce results that do not result in clearance or approval of our FDA marketing application. In
the event that we do not obtain FDA clearance or approval of the Viveve System for the treatment of vaginal laxity or sexual function, we
will be unable to promote it in the U.S. for those indications, and the ability to grow our revenues may be adversely affected.

 Our business is not currently profitable, and we may not be able to achieve profitability even if we are able to generate significant
revenue.

 As of December 31, 2017, we have incurred losses since inception of approximately $105.6 million. In 2017, we incurred a loss
of  $37.0  million  and  in  2016  a  loss  of  $20.1  million.  Even  though  our  revenue  may  increase,  we  expect  to  incur  significant  additional
losses while we grow and expand our business. We cannot predict if and when we will achieve profitability. Our failure to achieve and
sustain profitability could negatively impact the market price of our common stock and may require us to seek additional financing for our
business. There are no assurances that we will be able to obtain any additional financing or that any such financing will be on terms that
are favorable to us.

24

 
 
 
 
 
 
 
  
 
 
If there is not sufficient consumer demand for the procedures performed with our products, demand for our products could decline,
which would adversely affect our operating results. 

The  medical  device  and  aesthetic  markets  in  which  we  operate  are  particularly  vulnerable  to  economic  trends.  The  procedures
performed using our aesthetic treatment systems are elective procedures that are not reimbursable through government or private health
insurance. The cost of these elective procedures must be borne by the patient. As a result, the decision to undergo a procedure that uses our
products may be influenced by the cost. 

Consumer  demand,  and  therefore  our  business,  is  sensitive  to  a  number  of  factors  that  affect  consumer  spending,  including
political and macroeconomic conditions, health of credit markets, disposable consumer income levels, consumer debt levels, interest rates,
consumer  confidence  and  other  factors.  If  there  is  not  sufficient  consumer  demand  for  the  procedures  performed  with  our  products,
practitioner demand for our products would decline, and our business would suffer. 

It is difficult to forecast future performance, which may cause our financial results to fluctuate unpredictably.

 Our limited operating history makes it difficult to predict future performance. Additionally, the demand for Geneveve may vary
from quarter to quarter. A number of factors, over which we have limited or no control, may contribute to fluctuations in our financial
results, such as:

● delays in receipt of anticipated purchase orders;
● performance of our independent distributors;
● positive or negative media coverage of the Geneveve Treatment or products of our competitors;
● our ability to obtain further regulatory clearances or approvals;
● delays in, or failure of, product and component deliveries by our subcontractors and suppliers;
● customer response to the introduction of new product offerings; and
● fluctuations in foreign currency.

Our limited operating history has limited our ability to determine an appropriate sales price for our products.

 Our historical operating performance has limited our ability to determine the proper sales prices for Geneveve and the single-use
treatment  tips.  Establishing  appropriate  pricing  for  our  capital  equipment  and  components  has  been  challenging  because  there  have  not
existed directly comparable competitive products. We may experience similar pricing challenges in the future as we enter new markets or
introduce new products, which could have an unanticipated negative impact on our financial performance.

If  there  is  not  sufficient  patient  demand  for  our  treatments,  practitioner  demand  for the  Viveve  System   could  drop,  resulting  in
unfavorable operating results.

 All procedures performed using the Viveve System are elective procedures, the cost of which must be borne by the patient and
are  not  reimbursable  through  government  or  private  health  insurance.  The  decision  to  undergo  a  Geneveve  treatment  is  thus  driven  by
consumer demand, which may be influenced by a number of factors, such as:

● whether our marketing efforts directed toward increasing consumer awareness of Geneveve, for which we have limited

experience and resources and indications, are successful;

● the extent to which physicians recommend Geneveve to their patients;
● the cost, safety and effectiveness of Geneveve versus alternative treatments;

25

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
● general consumer sentiment about the benefits and risks of such procedures; and
● consumer confidence, which may be impacted by economic and political conditions.

Our financial performance could be materially harmed in the event that any of the above factors discourage patients from seeking

Geneveve.

The  failure  of  Geneveve  to  meet  patient  expectations  or  the  occurrence  of  unpleasant  side  effects  from  a  Geneveve treatment  could
impair our financial performance.

 Our future success depends upon patients having a positive experience with Geneveve in order to increase physician demand for
our  products,  as  a  result  of  positive  feedback  and  word-of-mouth  referrals.  Patients  may  be  dissatisfied  if  their  expectations  of  the
procedure, side effects and results, among other things, are not met. Despite what we believe to be the safety of the Geneveve treatment,
patients may experience undesirable side-effects such as temporary swelling or reddening of the treated tissue. Experiencing any of these
side effects could discourage a patient from completing a Geneveve treatment or discourage a patient from having future procedures or
referring  Geneveve  to  others.  In  order  to  generate  referral  business,  we  believe  that  patients  must  be  satisfied  with  the  effectiveness  of
Geneveve. Results obtained from Geneveve are subjective and may be subtle. Geneveve may produce results that may not meet patients’
expectations.  If  patients  are  not  satisfied  with  the  procedure  or  feel  that  it  is  too  expensive  for  the  results  obtained,  our  reputation  and
future sales will suffer.

Our success depends on growing physician adoption of the Viveve System and continued use of treatment tips.

 Some of our target physician customers already own self-pay device products. Our ability to grow our business and convince
physicians to purchase a Viveve System depends on the success of our sales and marketing efforts. Our business model involves both a
capital equipment purchase and continued purchases by our customers of single-use treatment tips and ancillary consumables. This may be
a novel business model for many potential customers who may be used to competing products that are exclusively capital equipment, such
as many laser-based systems. We must be able to demonstrate that the cost of the Viveve System and the revenue that the physician can
derive from performing procedures using it are compelling when compared to the cost and revenue associated with alternative products or
therapies. When marketing to plastic surgeons, we must also, in some cases, overcome a bias against non-invasive procedures. If we are
unable to increase physician adoption of our device and use of the treatment tips, our financial performance will be adversely affected.

To successfully market and sell the Viveve System internationally, we must address many issues with which we have limited experience.

Sales  outside  the  U.S.  accounted  for 28%  of  our  revenue  during  the  year  ended  December  31,  2017.  Sales  outside  the  U.S.
accounted for 96% and 100% of our revenue during the years ended December 31, 2016 and 2015, respectively. International sales are
subject to a number of risks, including:

● difficulties in staffing and managing international operations;
● difficulties in penetrating markets in which our competitors’ products may be more established; 
● reduced or no protection for intellectual property rights in some countries;
● export restrictions, trade regulations and foreign tax laws;
● fluctuating foreign currency exchange rates;
● foreign certification and regulatory clearance or approval requirements;
● difficulties in developing effective marketing campaigns for unfamiliar, foreign countries;
● customs clearance and shipping delays;
● political and economic instability; and
● preference for locally produced products.

If one or more of these risks were realized, it could require us to dedicate significant resources to remedy the situation, and even

if we are able to find a solution, our revenues may still decline.

26

 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
  
We depend on distributors to market and sell  the Viveve System   internationally.  If  they  are  not  successful,  our  marketing  and  sales
efforts will be harmed.

 We currently depend exclusively on third-party distributors to sell and service the Viveve System internationally and to train our
international customers, and if these distributors terminate their relationships with us or under-perform, we may be unable to maintain or
increase  our  level  of  international  revenue.  We  will  also  need  to  engage  additional  international  distributors  to  grow  our  business  and
expand the territories in which we sell the Viveve System. Distributors may not commit the necessary resources to market, sell and service
our  device  to  the  level  of  our  expectations.  If  current  or  future  distributors  do  not  perform  adequately,  or  if  we  are  unable  to  engage
distributors in particular geographic areas, our revenue from international operations will be adversely affected.

 We currently have limited sales and marketing resources or experience and failure to build and manage a sales force or to market and
distribute the Viveve System effectively could have a material adverse effect on our business.

 We  expect  to  rely  on  a  direct  sales  force  to  sell  the  Viveve  System  in  the  U.S.  In  order  to  meet  our  future  anticipated  sales
objectives, we expect to grow our domestic sales organization significantly over the next several years. There are significant risks involved
in building and managing our sales organization, including risks related to our ability to:

● hire qualified individuals as needed;
● provide adequate training for the effective sale of our device; and
● retain and motivate sales employees.

 It is difficult to predict how well our sales force will perform. Our failure to adequately address these risks could have a material
adverse  effect  on  our  ability  to  sell  the  Viveve  System,  causing  our  revenue  to  be  lower  than  expected  and  harming  our  results  of
operations.

Competition  among  providers  of  devices  for  the  medical  device  and  aesthetics  markets  is  characterized  by  rapid  innovation,  and  we
must continuously innovate technology and develop new products or our revenue may decline.

While we attempt to protect our technology through patents and other intellectual property rights, there are few barriers to entry
that would prevent new entrants or existing competitors from developing products that compete directly with our products. For example,
while we believe our monopolar RF technology maintains a strong intellectual property position, there may be other companies employing
competing  technologies  which  claim  to  have  a  similar  clinical  effect  to  our  technology. Additionally,  there  are  others  who  may  market
monopolar  RF  technology  for  competing  purposes  in  a  direct  challenge  to  our  intellectual  property  position. As  we  continue  to  create
market demand for a non-surgical, non-invasive way to treat vaginal laxity and sexual dysfunction, competitors may enter the market with
other products making similar or superior claims. We expect that any competitive advantage we may enjoy from our current and future
innovations may diminish over time, as companies successfully respond to our innovations, or create their own. Consequently, we believe
that we will have to continuously innovate and improve our technology or develop new products to compete successfully. If we are unable
to  develop  new  products  or  innovate  successfully,  the  Viveve  System  could  become  obsolete  and  our  revenue  will  decline  as  our
customers purchase competing products.

27

 
 
 
 
 
 
 
 
 
 
  
   
 
We outsource the manufacturing and repair of key elements of the Viveve System to a single manufacturing partner.

We  outsource  the  manufacture  and  repair  of  the  Viveve  System  to  a  single  contract  manufacturer,  Stellartech.  If  Stellartech’s
operations are interrupted or if Stellartech is unable to meet our delivery requirements due to capacity limitations or other constraints, we
may be limited in our ability to fulfill new customer orders or to repair equipment at current customer sites, and we may be required to
seek  new  manufacturing  partners  in  the  future.  Stellartech  has  limited  manufacturing  capacity,  is  itself  dependent  upon  third-party
suppliers  and  is  dependent  on  trained  technical  labor  to  effectively  repair  components  making  up  the  Viveve  System.  In  addition,
Stellartech  is  a  medical  device  manufacturer  and  is  required  to  demonstrate  and  maintain  compliance  with  the  FDA’s  Quality  System
Regulation, or QSR. If Stellartech or any future manufacturing partner fails to comply with the FDA’s QSR, its manufacturing and repair
operations could be halted. In addition, both the availability of our product to support the fulfillment of new customer orders as well as our
ability  to  repair  those  products  installed  at  current  customer  sites  would  be  impaired.  In  addition,  as  of  the  date  of  this  report,  the
development and manufacturing agreement under which Viveve and Stellartech operate has expired without any subsequent extension or
renewal  by  the  parties  and  the  minimum  conditions  to  the  licenses  granted  therein  have  not  been  satisfied  by  us. Although  the  parties
continue  to  operate  under  the  terms  of  this  agreement,  our  manufacturing  operations  could  be  adversely  impacted  if  we  are  unable  to
enforce Stellartech’s performance under this agreement, or enter into a new agreement with Stellartech, or a potential new manufacturer, if
necessary, upon favorable terms or at all.

Our manufacturing operations and those of our key manufacturing subcontractors are dependent upon third-party suppliers, making
us vulnerable to supply shortages and price fluctuations, which could harm our business.

 The  single  source  supply  of  the  Viveve  System  from  Stellartech  could  not  be  replaced  without  significant  effort  and  delay  in
production. Also, several other components and materials that comprise our device are currently manufactured by a single supplier or a
limited number of suppliers. In many of these cases, we have not yet qualified alternate suppliers and we rely upon purchase orders, rather
than long-term supply agreements. A supply interruption or an increase in demand beyond our current suppliers’ capabilities could harm
our  ability  to  manufacture  the  Viveve  System  until  new  sources  of  supply  are  identified  and  qualified.  Our  reliance  on  these  suppliers
subjects us to a number of risks that could harm our business, including:

● interruption of supply resulting from modifications to or discontinuation of a supplier’s operations;
● delays in product shipments resulting from uncorrected defects, reliability issues or a supplier’s variation in a component;
● a lack of long-term supply arrangements for key components with our suppliers;
● inability to obtain adequate supply in a timely manner, or to obtain adequate supply on commercially reasonable terms;
● difficulty locating and qualifying alternative suppliers for our components in a timely manner;
● production delays related to the evaluation and testing of products from alternative suppliers, and corresponding regulatory

qualifications;

● delay in delivery due to suppliers prioritizing other customer orders over our orders;
● damage to our brand reputation caused by defective components produced by our suppliers;
● increased cost of our warranty program due to product repair or replacement based upon defects in components produced by

our suppliers; and

● fluctuation in delivery by our suppliers due to changes in demand from us or from their other customers.

Any  interruption  in  the  supply  of  components  or  materials,  or  our  inability  to  obtain  substitute  components  or  materials  from
alternate sources at acceptable prices in a timely manner, could impair our ability to meet the demand of our customers, which would have
an adverse effect on our business.

If, in the future, we decide to perform additional manufacturing functions internally that we currently outsource, our business could be
harmed by our limited manufacturing experience and related capabilities.

In  the  future,  for  financial  or  operational  purposes,  we  may  elect  to  perform  component  or  system  manufacturing  functions
internally.  Our  limited  experience  with  manufacturing  processes  could  lead  to  difficulties  in  producing  sufficient  quan tities  of
manufactured items that meet our quality standards and that comply with applicable regulatory requirements in a timely and cost-effective
manner. In addition, if we experience these types of manufacturing difficulties, it may be expensive and time consuming to engage a new
or previous subcontractor or supplier to fulfill our replacement manufacturing needs. The occurrence of any of these events could harm
our business.

28

 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
If the Viveve System malfunctions or if we discover a manufacturing defect that could lead to a malfunction, we may have to initiate a
product recall or replace components, which could adversely impact our business.

Problems  in  our  manufacturing  processes,  or  those  of  our  manufacturers  or  subcontractors,  which  lead  to  an  actual or  possible
malfunction in any of the components of our device, may require us to recall product from customers or replace components and could
disrupt our operations. For example, in December 2012, we began replacing handpiece assemblies that were causing system malfunctions
due to fiber optic damage that occurred during the manufacturing process. We subsequently worked with our manufacturer to redesign and
test the reliability of the newly designed handpiece. The problem was resolved within several weeks and did not have a significant impact
on  our  ability  to  supply  products  to  our  customers  or,  more  generally,  on  our  results  of  operations.  However,  our  results  of  operations,
reputation  and  market  acceptance  of  our  products  could  be  harmed  if  we  encounter  difficulties  in  manufacturing  that  result  in  a  more
significant issue or significant patient injury and delays our ability to fill customer orders.

 We may not be able to develop an alternative cooling module that will be in compliance with changing environmental regulations in a
timely or cost-effective manner.

Our cooling module relies upon a hydrofluorocarbon, or HFC, called R134a, to protect the outer layer of the tissue from over-
heating  while  the  device  delivers  RF  energy  to  the  submucosal  tissue.  New  environmental  regulations  phasing  out  HFCs  over  the  next
decade  have  been  adopted  or  are  under  consideration  in  a  number  of  countries.  Since  2007,  European  Union  directives  aimed  at  the
automotive industry require the phase-out of HFCs and prohibit the introduction of new products incorporating HFCs and it is currently
anticipated  that  such  directives  may  impact  the  medical  device  industry. As  a  result,  if  we  are  unable  to  develop  an  alternative  cooling
module for our device which is not dependent on HFCs in a timely or cost-effective manner, the Viveve System may not be in compliance
with  environmental  regulations,  which  could  result  in  fines,  civil  penalties  and  the  inability  to  sell  our  products  in  certain  major
international markets.

 In addition, the impending restrictions on HFCs have reduced their current availability, as suppliers have less of an incentive to
expand production capacity or maintain existing capacity. This change in supply could expose us to supply shortages or increased prices
for  R134a,  which  could  impair  our  ability  to  manufacture  our  device  and  adversely  affect  our  results  or  operations.  HFCs  may  also  be
classified by some countries as a hazardous substance and, therefore, subject to significant shipping surcharges that may negatively impact
profit margins.

We rely on a limited number of suppliers and third-party manufacturers, and if they are unable or unwilling to continue to work with
us, our business could be materially adversely affected.

 We  rely  on  a  limited  number  of  suppliers  and  third-party  manufacturers.  Our  reliance  on  them  increases  our  risk  since  in  the
event of an interruption from one or more of them, we may not be able to develop alternative resources without incurring additional costs
or delays. For example, we entered into a Coupling Fluid License and Product Supply Agreement with Solta Medical (“Solta”) pursuant to
which Solta agreed to grant to us a license for the coupling fluid and supply the coupling fluid at preferred pricing for two years and at
non-preferred  pricing  after  two  years.  The  agreement  was  for  an  initial  term  of  three  years,  after  which  it  continues  to  remain  in  effect
unless  and  until  terminated  in  accordance  with  the  terms  therein.  We  use  the  cryogen  cooling  method  and  coupling  fluid  with  our
compatible radiofrequency medical device for the purpose of conducting our clinical trials as well as for commercial purposes. Since we
currently do not have any alternative sources of cryogen, if Solta refuses to sell to us for commercial reasons, or otherwise, our business
could be materially adversely affected.

We  forecast  sales  to  determine  requirements  for  components  and  materials  used  in  Geneveve,  and  if  our  forecasts  are  incorrect,  we
may experience delays in shipments or increased inventory costs.

We  keep  limited  materials,  components  and  finished  product  on  hand.  To  manage  our  manufacturing  operations  with  our
suppliers, we forecast anticipated product orders and material requirements to predict our inventory needs up to six months in advance and
enter into purchase orders on the basis of these requirements. Our limited historical experience may not provide us with enough data to
accurately  predict  future  demand.  If  our  business  expands,  our  demand  for  components  and  materials  would  increase  and  our  suppliers
may be unable to meet our demand. If we overestimate our component and material requirements, we will have excess inventory, which
would increase our expenses. If we underestimate our component and material requirements, we may have inadequate inventory, which
could interrupt, delay or prevent delivery of the Viveve System to our customers. Any of these occurrences would negatively affect our
financial performance and the level of satisfaction that our customers have with our business.

29

 
 
 
   
 
 
 
 
 
 
 
Even  though  we  require  training  for  users  of the Viveve System   and  we  do  not  sell it  to  non-physicians,  there  exists  a  potential  for
misuse, which could harm our reputation and our business.

 Outside of the U.S., our independent distributors sell in many jurisdictions that do not require specific qualifications or training
for purchasers or operators of the Viveve System. We do not supervise the procedures performed with the device, nor can we be assured
that direct physician supervision of our equipment occurs according to our recommendations. We and our distributors require purchasers of
our device to undergo an initial training session as a condition of purchase, but do not require ongoing training. In addition, we prohibit the
sale of the device to companies that rent it to third parties, but we cannot prevent an otherwise qualified physician from contracting with a
rental company in violation of his or her purchase agreement with us.

 In the U.S., we only sell the Viveve System to licensed physicians who have met certain training requirements. However, current
federal regulations will allow us to sell our device to “licensed practitioners,” The definition of “licensed practitioners” varies from state to
state. As a result, the Viveve System may be operated by licensed practitioners with varying levels of training, and in many states by non-
physicians,  including  physician  assistants,  registered  nurses  and  nurse  practitioners.  Thus,  in  some  states,  the  definition  of  “licensed
practitioner” may result in the legal use of the Viveve System by non-physicians.

  The  use  of  our  device  by  non-physicians,  as  well  as  noncompliance  with  the  operating  guidelines  set  forth  in  our  training
programs, may result in product misuse and adverse treatment outcomes, which could harm our reputation and expose us to costly product
liability litigation.

Product liability suits could be brought against us due to defective design, labeling, material or workmanship, or misuse of the Viveve
System,  and  could  result  in  expensive  and  time-consuming  litigation,  payment  of  substantial  damages  and  an  increase  in  our
insurance rates.

 If  the  Viveve  System  is  defectively  designed,  manufactured  or  labeled,  contains  defective  components  or  is  misused,  we  may
become subject to substantial and costly litigation by our customers or their patients. Misusing the device or failing to adhere to operating
guidelines could cause serious adverse events. In addition, if our operating guidelines are found to be inadequate, we may be subject to
liability.  We  may,  in  the  future,  be  involved  in  litigation  related  to  the  use  of  the  device.  Product  liability  claims  could  divert
management’s  attention  from  our  business,  be  expensive  to  defend  and  result  in  sizable  damage  awards  against  us.  We  may  not  have
sufficient insurance coverage for all future claims. We may not be able to obtain insurance in amounts or scope sufficient to provide us
with  adequate  coverage  against  all  potential  liabilities. Any  product  liability  claims  brought  against  us,  with  or  without  merit,  could
increase our product liability insurance rates or prevent us from securing continuing coverage, could harm our reputation in the industry
and  reduce  product  sales.  Product  liability  claims  in  excess  of  our  insurance  coverage  would  be  paid  out  of  cash  reserves,  harming  our
financial condition and adversely affecting our operating results.

After-market modifications to treatment tips by third parties and the development of counterfeit products could reduce our sales, expose
us to product liability litigation and dilute our brand quality.

 Third parties may introduce adulterated after-market modifications to our treatment tips, which enable re-use of treatment tips in
multiple procedures. Because the treatment tips are designed to withstand a finite number of pulses, modifications intended to increase the
number of pulses could result in patient injuries caused by the use of worn-out or damaged treatment tips. In addition, third parties may
seek to develop counterfeit products that are compatible with the Viveve System and available to practitioners at lower prices. If security
features incorporated into the design of the device are unable to prevent after-market modifications to the treatment tips or the introduction
of  counterfeit  products,  we  could  be  subject  to  reduced  sales,  product  liability  lawsuits  resulting  from  the  use  of  damaged  or  defective
goods and damage to our reputation.

30

 
 
 
  
 
 
 
 
 
 
We depend on skilled and experienced personnel to operate our business effectively. If we are unable to recruit, hire and retain these
employees, our ability to manage and expand our business will be harmed, which would impair our future revenue and profitability.

  Our  success  largely  depends  on  the  skills,  experience  and  efforts  of  our  officers  and  other  key  employees.  While  we  have
employment  contracts  with  our  Chief  Executive  Officer  and  our  Chief  Financial  Officer,  these  officers  and  other  key  employees  may
terminate their employment at any time. The loss of any senior management team members could weaken our management expertise and
harm our business.

 Our ability to retain our skilled labor force and our success in attracting and hiring new skilled employees will be a critical factor
in  determining  whether  we  will  be  successful  in  the  future.  We  may  not  be  able  to  meet  our  future  hiring  needs  or  retain  existing
personnel. We will face particularly significant challenges and risks in hiring, training, managing and retaining engineering and sales and
marketing employees, as well as independent distributors, most of whom are geographically dispersed and must be trained in the use of our
device and benefits of Geneveve. Failure to attract and retain personnel, particularly technical and sales and marketing personnel, would
materially harm our ability to compete effectively and grow our business.

 Any acquisitions or in-licenses that we make could disrupt our business and harm our financial condition.

 We  expect  to  evaluate  potential  strategic  acquisitions  of  complementary  businesses,  products  or  technologies.  We  may  also
consider  joint  ventures  and  other  collaborative  projects,  including  in-license  opportunities.  We  may  not  be  able  to  identify  appropriate
acquisition  candidates  or  strategic  partners,  or  successfully  negotiate,  finance  or  integrate  acquisitions  of  any  businesses,  products  or
technologies, as applicable, on favorable terms or at all. Furthermore, the integration of any acquisition or in-license and management of
any collaborative project may divert management’s time and resources from our business and disrupt our operations. We do not have any
experience with acquiring companies or products or in-licensing of technologies. If we decide to expand our product offerings, we may
spend time and money on projects that do not increase our revenues. Our inability to identify and secure such opportunities may harm our
financial condition and our ability to compete and grow our business.

Our ability to use our net operating losses to offset future taxable income may be subject to certain limitations.

Our ability to use our net operating losses to offset future taxable income may be subject to certain limitations. As of  December
31,  2017,  we  had  federal  and  state  net  operating  loss  carryforwards  (“NOLs”),  of  approximately  $78.9  million  and  $50.5  million,
respectively, due to prior period losses. In general, under Section 382 of the Internal Revenue Code of 1986, as amended (the “Code”), a
corporation that undergoes an “ownership change” can be subject to limitations on its ability to utilize its NOLs to offset future taxable
income. Our existing NOLs may be subject to limitations arising from past ownership changes, including in connection with this offering.
Future changes in our stock ownership, some of which are outside of our control, could result in an ownership change under Section 382 of
the Code.  In addition, under the Tax Cuts and Jobs Act (the “Tax Act”), the amount of future NOLs that we are permitted to deduct in any
taxable  year  is  limited  to  80%  of  our  taxable  income  in  such  year,  where  taxable  income  is  determined  without  regard  to  the  NOL
deduction  itself.  In  addition,  the  Tax Act  generally  eliminates  the  ability  to  carry  back  any  future  NOL  to  prior  taxable  years,  while
allowing unused future NOLs to be carried forward indefinitely. There is a risk that due to changes under the Tax Act, regulatory changes,
or other unforeseen reasons, our existing NOLs could expire or otherwise be unavailable to offset future income tax liabilities. For these
reasons, we may not be able to realize a tax benefit from the use of our NOLs, whether or not we attain profitability.

31

 
 
 
 
  
 
 
 
 
 Risks Related to Regulatory Matters

We or our distributors may be unable to obtain or maintain international regulatory clearances or approvals  for our current or future
products, or our distributors may be unable to obtain necessary qualifications, which could harm our business.

  Sales  of  the  Viveve  System  internationally  are  subject  to  foreign  regulatory  requirements  that  vary  widely  from  country  to
country. In addition, the FDA regulates exports of medical devices from the U.S. Complying with international regulatory requirements
can  be  an  expensive  and  time-consuming  process,  and  marketing  approval  or  clearance  is  not  certain.  The  time  required  to  obtain
clearances or approvals, if required by other countries, may be longer than that required for FDA clearance or approvals, and requirements
for  such  clearances  or  approvals  may  significantly  differ  from  FDA  requirements.  We  may  rely  on  third-party  distributors  to  obtain
regulatory clearances and approvals required in other countries, and these distributors may be unable to obtain or maintain such clearances
or approvals. Our distributors may also incur significant costs in attempting to obtain and in maintaining foreign regulatory approvals or
clearances,  which  could  increase  the  difficulty  of  attracting  and  retaining  qualified  distributors.  If  our  distributors  experience  delays  in
receiving  necessary  qualifications,  clearances  or  approvals  to  market  our  products  outside  the  U.S.,  or  if  they  fail  to  receive  those
qualifications, clearances or approvals, we may be unable to market our products or enhancements in international markets effectively, or
at all.

  Foreign governmental authorities that regulate the manufacture and sale of medical devices have become increasingly stringent
and, to the extent we market and sell our products outside of the U.S., we may be subject to rigorous international regulation in the future.
In these circumstances, we would be required to rely on our foreign independent distributors to comply with the varying regulations, and
any failures on their part could result in restrictions on the sale of our product in foreign countries.

 If we fail to maintain regulatory approvals and clearances, or if we are unable to obtain, or experience significant delays in obtaining,
FDA  clearances  or  approvals  for the  Viveve  System   or  any  future  products  we  may  develop  or  acquire,  including  product
enhancements, our business and results of operations could be adversely affected.

 The Viveve System is, and any future products we may acquire or develop will be, subject to rigorous regulation by the FDA and
numerous other federal, state and foreign governmental authorities. The process of obtaining regulatory clearances or approvals to market
a medical device can be costly and time consuming, and we may not be able to obtain these clearances or approvals on a timely basis, if at
all.  In  particular,  the  FDA  permits  commercial  distribution  of  a  new  medical  device  only  after  the  device  has  received  clearance  under
section 510(k) of the Federal Food, Drug, and Cosmetic Act, or FDCA, (unless the device is exempt from the 510(k) requirements), has
been classified pursuant to a de novo classification request, or is the subject of an approved premarket approval application, or PMA. The
FDA  will  permit  marketing  of  a  lower  risk  medical  device  through  the  510(k)  process  if  the  manufacturer  demonstrates  that  the  new
product  is  substantially  equivalent  to  a  previously  cleared  and  legally  marketed  device  or  a  device  that  was  in  commercial  distribution
before May 28, 1976 for which the FDA has not yet called for the submission of PMA, referred to as a predicate device. Devices deemed
to pose the greatest risk, such as life-sustaining, life-supporting, or implantable devices, or devices not deemed substantially equivalent to a
previously  cleared  device,  require  the  approval  of  a  PMA.  The  PMA  process  is  more  costly,  lengthy  and  uncertain  than  the  510(k)
clearance process. A PMA application must be supported by extensive data, including, but not limited to, technical, preclinical, clinical
trial, manufacturing and labeling data, to demonstrate to the FDA a reasonable assurance of the safety and efficacy of the device for its
intended use.

If  FDA  has  not  issued  a  regulation  classifying  a  particular  type  of  device  as  Class  I,  and  if  there  is  no  known  predicate  for  a
device, the device is automatically Class III, regardless of the risk the device poses. If a device is automatically/statutorily classified into
Class III in this manner, a company can petition FDA to reclassify the category of devices into Class II or Class I via a process known as
“Evaluation of Automatic Class III Designation,” which is typically referred to as the de novo process. The direct de novo process allows a
company  to  request  that  a  new  product  classification  be  established  without  the  company  first  submitting  a  510(k)  notification  for  the
device.      Our  plan  is  to  seek  FDA  authorization  to  market  Geneveve  for  the  treatment  of  vaginal  tissue  to  improve  sexual  function  by
utilizing the direct de novo process. However, we cannot predict when or if such de novo classification will be obtained. If FDA fails to
reclassify the device pursuant to the de novo process, we will be required to seek FDA premarket approval (via the more stringent PMA
process) for the Viveve System. Delays in receipt of FDA clearance or approval or failure to receive FDA clearance or approval could
adversely affect our business, results of operations and future growth prospects.

32

 
 
 
  
 
 
 
  
 
Our marketed products may be used by physicians for indications that are not cleared by the FDA. If the FDA finds that we marketed
our products in a manner that promoted off-label use, we may be subject to civil or criminal penalties.

Under the FDCA and other laws, we are prohibited from promoting our products for off-label uses. This means that we may not
make claims about the use of any of our marketed medical device products outside of their approved or cleared indications, and that our
website, advertising promotional materials and training methods may not promote or encourage unapproved uses. Therefore, we may not
provide  information  to  physicians  or  patients  that  promote  off-label  uses,  except  in  limited  circumstances,  such  as  in  response  to
unsolicited  requests  for  off-label  information  or  the  distribution  of  scientific  and  medical  publications  under  certain  circumstances.  The
FDA does not generally restrict physicians from prescribing products for off-label uses (or using products in an off-label manner) in their
practice of medicine. Should the FDA determine that our activities constitute the promotion of off-label uses, the FDA could bring action
to prevent us from distributing our devices for the off-label use and could impose fines and penalties on us and our executives. In addition,
failure to follow FDA rules and guidelines relating to promotion and advertising can result in, among other things, the FDA’s refusal to
approve or clear products, the withdrawal of an approved/cleared product from the market, product recalls, fines, disgorgement of profits,
operating restrictions, injunctions or criminal prosecutions. Any of these adverse regulatory actions could result in substantial costs and
could  significantly  and  adversely  impact  our  reputation  and  divert  management’s  attention  and  resources,  which  could  have  a  material
adverse effect on our business.

If the Office of Inspector General within the Department of Health and Human Services, the DOJ, or another federal or state agency
determines  that  we  have  promoted  off-label  use  of  our  products,  we  may  be  subject  to  various  penalties,  including  civil  or  criminal
penalties, and the off-label use of our products may result in injuries that lead to product liability suits, which could be costly to our
business.

In addition to the FDA restrictions on our marketed products, other state and federal healthcare laws have been applied by DOJ
and state attorneys general to restrict certain marketing practices in the medical device industry. While physicians may generally prescribe
and administer products for off-label uses, if we engage in off-label promotion, we may be subject to civil or criminal penalties including
significant fines and could be prohibited from participating in government healthcare programs such as Medicaid and Medicare. Even if we
are  successful  in  resolving  such  matters  without  incurring  penalties,  responding  to  investigations  or  prosecutions  will  likely  result  in
substantial  costs  and  could  significantly  and  adversely  impact  our  reputation  and  divert  management’s  attention  and  resources,  which
could  have  a  material  adverse  effect  on  our  business,  operating  results,  financial  condition  and  ability  to  finance  our  operations.  In
addition,  the  off-label  use  of  our  products  may  increase  the  risk  of  injury  to  patients,  and,  in  turn,  the  risk  of  product  liability  claims.
Product  liability  claims  are  expensive  to  defend  and  could  divert  our  management’s  attention  and  result  in  substantial  damage  awards
against us.

If we modify an FDA-cleared device, we may need to seek and obtain new clearances, which, if not granted, would prevent the sale of
our modified product or require us to redesign the product.

 Any modifications to an FDA-cleared device that could significantly affect its safety or effectiveness or that would constitute a
major change in its intended use would require a new 510(k) clearance or possibly a premarket approval. We may not be able to obtain
additional 510(k) clearances or premarket approvals for new products or for modifications to, or additional indications for, our existing
product in a timely fashion, or at all. Delays in obtaining future clearances or approvals would adversely affect our ability to introduce new
or  enhanced  products  in  a  timely  manner,  which  in  turn  could  harm  our  revenue  and  potential  future  profitability.  We  have  made
modifications  to  our  device  in  the  past  and  may  make  additional  modifications  in  the  future  that  we  believe  do  not  or  will  not  require
additional  clearances  or  approvals.  If  the  FDA  disagrees,  and  requires  new  clearances  or  approvals  for  the  modifications,  we  may  be
required  to  recall  and  to  stop  marketing  the  modified  device,  which  could  harm  our  operating  results  and  require  us  to  redesign  the
product.

Clinical  trials  necessary  to  support  a  510(k)notification,  de  novo  petition  or  PMA  application  will  be  expensive  and  will  require  the
enrollment  of  large  numbers  of  patients.  Suitable  patients  may  be  difficult  to  identify  and  recruit.  Delays  or  failures  in  our  clinical
trials  may  prevent  us  from  commercializing  our  current  product  or  any  modified  or  new  products  and  will  adversely  affect  our
business, operating results and prospects.

  The  FDA  has  asked  us  to  conduct  a  clinical  study,  pursuant  to  the  agency’s  investigational  device  exemption,  or  IDE,
regulations, to support a future product submission for the Viveve System. Initiating and completing clinical trials necessary to support a
510(k) notification, de novo petition, or PMA application for the Viveve System, as well as other possible future product candidates, will
be time consuming and expensive and the outcome is uncertain. Moreover, the results of early clinical trials are not necessarily predictive
of future results, and any product we advance into clinical trials may not have favorable results in later clinical trials.

33

 
 
 
  
 
 
 
  
 
 
Conducting successful clinical studies will require the enrollment of patients, and suitable patients may be difficult to identify and
recruit. Patient enrollment in clinical trials and completion of patient participation and follow-up depends on many factors, including the
size  of  the  patient  population,  the  nature  of  the  trial  protocol,  the  desirability  of,  or  the  discomforts  and  risks  associated  with,  the
treatments  received  by  enrolled  subjects,  the  availability  of  appropriate  clinical  trial  investigators  and  support  staff,  the  proximity  of
patients to clinical sites, the ability of patients to comply with the eligibility and exclusion criteria for participation in the clinical trial and
patient  compliance.  For  example,  patients  may  be  discouraged  from  enrolling  in  our  clinical  trials  if  the  trial  protocol  requires  them  to
undergo extensive post-treatment procedures or follow-up to assess the safety and effectiveness of our product or if they determine that the
treatments received under the trial protocols are not desirable or involve unacceptable risk or discomfort.

 Development  of  sufficient  and  appropriate  clinical  protocols  to  demonstrate  safety  and  efficacy  are  required  and  we  may  not
adequately develop such protocols to support clearance or approval. Further, the FDA may require us to submit data on a greater number
of patients than we originally anticipated and/or for a longer follow-up period or change the data collection requirements or data analysis
applicable to our clinical trials. Delays in patient enrollment or failure of patients to continue to participate in a clinical trial may cause an
increase  in  costs  and  delays  in  the  approval  or  clearance  and  attempted  commercialization  of  our  product  or  result  in  the  failure  of  the
clinical trial. In addition, despite considerable time and expense invested in clinical trials, the FDA may not consider our data adequate to
demonstrate  safety  and  efficacy.  Such  increased  costs  and  delays  or  failures  could  adversely  affect  our  business,  operating  results  and
prospects.

If  the  third  parties  on  which  we  rely  to  conduct  our  clinical  trials  and  to  assist  us  with  preclinical  development  do  not  perform  as
contractually  required  or  expected,  we  may  not  be  able  to  obtain  the  regulatory  clearance  or  approval  which  would  permit  us  to
commercialize our products.

 We do not have the ability to independently conduct the preclinical studies and clinical trials for our product, therefore we must
rely  on  third  parties,  such  as  contract  research  organizations,  medical  institutions,  clinical  investigators  and  contract  laboratories  to
conduct the studies and trials. If these third parties do not successfully carry out their contractual duties or regulatory obligations or meet
expected deadlines, if these third parties need to be replaced, or if the quality or accuracy of the data they obtain is compromised due to the
failure to adhere to our clinical protocols or regulatory requirements or for other reasons, our preclinical development activities or clinical
trials may be extended, delayed, suspended or terminated, and we may not be able to obtain regulatory clearance or approval for, or be able
to successfully commercialize, our product on a timely basis, if at all. In that event, our business, operating results and prospects may be
adversely affected.

 The results of our clinical trials may not support our proposed product claims or may result in the discovery of adverse side effects.
Any of these events could have a material adverse impact on our business.  

 Even  if  our  clinical  trials  are  completed  as  planned,  it  cannot  be  certain  that  the  results  of  the  clinical  trials  will  support  our
proposed claims for the Viveve System, that the FDA or foreign authorities will agree with our conclusions regarding them or that even if
our  product  receives  regulatory  approval  or  clearance,  that  it  will  not  later  result  in  adverse  side  effects  that  limit  or  prevent  its  use.
Success in preclinical studies and early clinical trials does not ensure that later clinical trials will be successful, and we cannot be sure that
the  later  trials  will  replicate  the  results  of  prior  trials  and  preclinical  studies.  The  clinical  trial  process  may  fail  to  demonstrate  that  our
product  is  safe  and  effective  for  the  proposed  indicated  uses. Any  delay  of  our  clinical  trials  or  failure  by  the  FDA  or  other  foreign
authorities to accept our product claims will delay, or even prevent, our ability to commercialize our product and generate revenues.  

34

 
 
 
 
 
 
 
  
Even  if  our  product  is  approved  by  regulatory  authorities,  if  we  or  our  suppliers  fail  to  comply  with  ongoing  FDA  or  other  foreign
regulatory  authority  requirements,  or  if  we  experience  unanticipated  problems  with  our  product,  the  product  could  be  subject  to
restrictions or withdrawal from the market.

 Any product for which we obtain clearance or approval, and the manufacturing processes, reporting requirements, post-approval
clinical data and promotional activities for such product, will be subject to continued regulatory review, oversight and periodic inspections
by the FDA and other domestic and foreign regulatory bodies, such as the Food and Drug Branch of the CDHS. In particular, we and our
suppliers are required to comply with the FDA’s QSR, and International Standards Organization, or ISO, standards for the manufacture of
our  product  and  other  regulations  which  cover  the  methods  and  documentation  of  the  design,  testing,  production,  control,  quality
assurance, labeling, packaging, storage and shipping of any product for which we obtain clearance or approval. Regulatory bodies, such as
the  FDA,  enforce  the  QSR  and  other  regulations  through  periodic  inspections.  In  the  past,  our  Sunnyvale,  California  facility  has  been
inspected by the FDA and CDHS, and observations were noted. The FDA and CDHS have accepted our responses to these observations,
and  we  believe  that  we  are  in  substantial  compliance  with  the  QSR. Any  future  failure  by  us  or  one  of  our  suppliers  to  comply  with
applicable statutes and regulations administered by the FDA and other regulatory bodies, or the failure to timely and adequately respond to
any  adverse  inspectional  observations  or  product  safety  issues,  could  result  in,  among  other  things,  any  of  the  following  enforcement
actions and unanticipated expenditures to address or defend such actions:

● untitled letters, warning letters, fines, injunctions, consent decrees and civil penalties;
● customer notifications for repair, replacement or refunds;
● recall, detention or seizure of our products;
● operating restrictions or partial suspension or total shutdown of production;
● refusing or delaying our requests for 510(k) clearance, de novo classification, or premarket approval of new products or

modified products;
● operating restrictions;
● reclassifying a device that previously received a 510(k) clearance or withdrawing a PMA approval that was previously

granted;

● refusal to grant export approval for our product; or
● criminal prosecution.

If any of these actions were to occur it would harm our reputation and cause our product sales to suffer and may prevent us from
generating revenue. Furthermore, our third-party manufacturers may not currently be, or may not continue to be, in compliance with all
applicable regulatory requirements which could result in a failure to produce our product on a timely basis and in the required quantities, if
at all.

Even  if  regulatory  clearance  or  approval  of  a  product  is  granted  for  the  Viveve  System  or  future  products,  such  clearance  or
approval  may  be  subject  to  limitations  on  the  intended  uses  for  which  the  product  may  be  marketed  and  reduce  our  potential  to
successfully  commercialize  the  product  and  generate  revenue  from  the  product.  If  the  FDA  determines  that  our  promotional  materials,
labeling, training or other marketing or educational activities constitute promotion of an unapproved use, it could request that we cease or
modify our training or promotional materials or subject us to regulatory enforcement actions. It is also possible that other federal, state or
foreign enforcement authorities might take action if they consider our training or other promotional materials to constitute promotion of an
unapproved use, which could result in significant fines or penalties under other statutory authorities, such as laws prohibiting false claims
for reimbursement.

In  addition,  we  may  be  required  by  the  FDA  or  other  foreign  regulatory   bodies  to  conduct  costly  post-market  testing  and
surveillance  to  monitor  the  safety  or  effectiveness  of  our  products,  and  we  must  comply  with  medical  device  reporting  requirements,
including the reporting of adverse events and malfunctions related to our products. Later discovery of previously unknown problems with
our products, including unanticipated adverse events or adverse events of unanticipated severity or frequency, manufacturing problems, or
failure  to  comply  with  regulatory  requirements  such  as  the  QSR,  may  result  in  changes  to  labeling,  restrictions  on  such  products  or
manufacturing processes, withdrawal of the products from the market, voluntary or mandatory recalls, a requirement to repair, replace or
refund the cost of any medical device we manufacture or distribute, fines, suspension of regulatory approvals, product seizures, injunctions
or the imposition of civil or criminal penalties which would adversely affect our business, operating results and prospects.

35

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
The Viveve System  may also be subject to state regulations which are, in many instances, in flux. Changes in state regulations
may  impede  sales.  For  example,  federal  regulations  may  allow  the  device  to  be  sold  to,  or  on  the  order  of,  “licensed  practitioners,”  as
determined on a state-by-state basis. As a result, in some states, non-physicians may legally purchase and operate our device. However, a
state could change its regulations at any time, disallowing sales to particular types of end users. We cannot predict the impact or effect of
future legislation or regulations at the federal or state levels.

If we or our third-party manufacturers fail to comply with the FDA’s QSR, our business would suffer.

We and our third-party manufacturers are required to demonstrate and maintain complian ce with the FDA’s QSR. The QSR is a
complex  regulatory  scheme  that  covers  the  methods  and  documentation  of  the  design,  testing,  control,  manufacturing,  labeling,  quality
assurance,  packaging,  storage  and  shipping  of  our  product.  The  FDA  enforces  the  QSR  through  periodic  unannounced  inspections.  We
anticipate  that  in  the  future  we  will  be  subject  to  such  inspections.  Our  failure,  or  the  failure  of  our  third-party  manufacturers,  to  take
satisfactory corrective action in response to an adverse QSR inspection could result in enforcement actions, including a public warning
letter,  a  shutdown  of  our  manufacturing  operations,  a  recall  of  our  product,  civil  or  criminal  penalties  or  other  sanctions,  which  would
cause our reputation, sales and business to suffer.

If our product causes or contributes to a death or a serious injury, or malfunctions in certain ways, we will be subject to medical device
reporting regulations, which can result in voluntary corrective actions or agency enforcement actions.

  Under  the  FDA’s  medical  device  reporting  regulations,  medical  device  manufacturers  are  required  to  report  to  the  FDA
information that a device has or may have caused or contributed to a death or serious injury or has malfunctioned in a way that would be
likely to cause or contribute to death or serious injury if the malfunction of the device were to recur. If we fail to report these events to the
FDA within the required timeframes, or at all, the FDA could take enforcement action against us. Any such adverse event involving the
Viveve System or future products could result in future voluntary corrective actions, such as recalls or customer notifications, or agency
action, such as inspection or enforcement action. Any corrective action, whether voluntary or involuntary, as well as mounting a defense to
a legal action, if one were to be brought, would require the dedication of our time and capital, distract management from operating our
business, and may harm our reputation and financial results.

The Viveve System may, in the future, be subject to product recalls that could harm our reputation, business and financial results.

 The FDA and similar foreign governmental authorities have the authority to require the recall of commercialized products in the
event of material deficiencies or defects in design or manufacture. In the case of the FDA, the authority to require a recall must be based on
an  FDA  finding  that  there  is  a  reasonable  probability  that  the  device  would  cause  serious,  adverse  health  consequences  or  death.
Manufacturers may, under their own initiative, recall a product if any material deficiency in a device is found. A government-mandated or
voluntary recall by us or one of our distributors could occur as a result of component failures, manufacturing errors, design or labeling
defects or other deficiencies and issues. A recall of our product would divert managerial and financial resources and have an adverse effect
on our financial condition and results of operations. The FDA requires that certain classifications of recalls be reported to the FDA within
10 working days after the recall is initiated. Companies are required to maintain certain records of recalls, even if they are not reportable to
the FDA. In the future, we may initiate one or more voluntary correction or removal actions involving our product that we determine do
not  require  notification  to  the  FDA.  If  the  FDA  disagrees  with  our  determinations,  the  FDA  could  require  us  to  report  those  actions  as
recalls. A  future  recall  announcement  could  harm  our  reputation  with  customers  and  negatively  affect  our  sales.  In  addition,  the  FDA
could take enforcement action for failing to report the recalls when they were conducted.

Federal and state regulatory reforms may adversely affect our ability to s ell our product profitably.

 From  time  to  time,  legislation  is  drafted  and  introduced  in  Congress  that  could  significantly  change  the  statutory  provisions
governing the clearance or approval, manufacture and marketing of a medical device. In addition, FDA regulations and guidance are often
revised  or  reinterpreted  by  the  agency  in  ways  that  may  significantly  affect  our  business  and  our  product.  It  is  impossible  to  predict
whether legislative changes will be enacted or FDA regulations, guidance or interpretations will be changed, and what the impact of such
changes, if any, may be. 

36

 
 
 
 
 
  
 
 
  
 
 
 For example, in August 2010, the FDA issued its preliminary recommendations on reform of the 510(k) pre-market notification
process for medical devices. On January 19, 2011, the FDA announced its “Plan of Action” for implementing these recommendations. The
Plan of Action included 25 action items, most of which have now been implemented by the agency. In August 2016, the FDA released its
proposals for reforming long-standing procedures and requirements related to modifications to medical devices already on the market.  In
December 2016, Congress passed the 21st Century Cures Act, which makes multiple changes to FDA’s rules for medical devices as well
as for clinical trials, and Congress (passed the Medical Device User Fee reauthorization package in 2017.  

The  FDA  or  Congress  may  implement  other  reforms  in  the  future.  Future  reforms  could  have  the  effect  of  making  it  more
difficult and expensive for us to obtain FDA clearance or approval.  Such changes may also be made by legislators or regulators in the
foreign jurisdictions in which we do business and could similarly affect our operations and profitability in those markets.

 In addition, a state could change its statutes or regulations at any time, disallowing sales to particular types of end users or placing
restrictions  on  certain  chemicals,  such  as  those  used  in  our  cryogen.  We  cannot  predict  the  impact  or  effect  of  future  legislation  or
regulations at the federal or state levels, or in any foreign jurisdiction in which we do business.

Failure to comply with the U.S. Foreign Corrupt Practices Act and similar laws associated with our activities outside the U.S. could
subject us to penalties and other adverse consequences.

 A significant portion of our revenues is and will  be  from  jurisdictions  outside  of  the  U.S.  We  are  subject  to  the  U.S.  Foreign
Corrupt Practices Act, or the FCPA, which generally prohibits U.S. companies and their intermediaries from making payments to foreign
officials for the purpose of directing, obtaining or keeping business, and requires companies to maintain reasonable books and records and
a  system  of  internal  accounting  controls.  The  FCPA  applies  to  companies  and  individuals  alike,  including  company  directors,  officers,
employees and agents. Under the FCPA, U.S. companies may be held liable for the corrupt actions taken by employees, strategic or local
partners or other representatives. In addition, the government may seek to rely on a theory of successor liability and hold us responsible for
FCPA  violations  committed  by  companies  or  associated  with  assets  which  we  acquire.  In  recent  years,  the  medical  device  and
pharmaceutical industries have been a focus of the U.S. government’s FCPA enforcement priorities,  and  settlements  often  include  very
significant payments potentially consisting of millions of dollars. Other countries have similar laws to which we may be subject, including
the United Kingdom Bribery Act.

 In many foreign countries where we operate, particularly in countries with developing economies, it may be a local custom for
businesses to engage in practices that are prohibited by the FCPA or other similar laws and regulations. In contrast, we have implemented
a company policy requiring our employees and consultants to comply with the FCPA and similar laws. At the present time, we have not
conducted  formal  FCPA  compliance  training  for  our  foreign  distributors  and  partners,  but  we  are  in  the  process  of  devising  a  training
schedule  for  certain  of  our  employees,  agents  and  partners.  Nevertheless,  there  can  be  no  assurance  that  our  employees,  partners  and
agents, as well as those companies to which we outsource certain of our business operations, will not take actions in violation of the FCPA
or our policies for which we may be ultimately held responsible. As a result of our anticipated growth, our development of infrastructure
designed  to  identify  FCPA  matters  and  monitor  compliance  is  at  an  early  stage.  If  we  or  our  intermediaries  fail  to  comply  with  the
requirements  of  the  FCPA  or  similar  legislation,  governmental  authorities  in  the  U.S.  and  elsewhere  could  seek  to  impose  civil  and/or
criminal  fines  and  penalties  which  could  have  a  material  adverse  effect  on  our  reputation,  business,  operating  results  and  financial
conditions. We may also face collateral consequences, such as debarment and the loss of our export privileges. 

37

 
 
 
 
 
 
 
 
Viveve’s relationships with customers and healthcare providers and professionals may be subject to applicable anti-kickback,
fraud and abuse and other healthcare laws and regulations, as well as comparable state and foreign laws, which could expose Viveve
to criminal sanctions, civil penalties, contractual damages, reputational harm and diminished profits and future earnings. 

Healthcare  providers  and  physicians  play  a  primary  role  in  the  recommendation  and  prescription  of  any  medical  product,
including  the Viveve  System  marketed  by  the  Company.  Viveve’s  future  arrangements  with  customers,  healthcare  providers  and  other
medical  professionals  could  expose  Viveve  to  broadly  applicable  fraud  and  abuse  and  other  healthcare  laws  and  regulations  that  may
constrain the business or financial arrangements and relationships through which Viveve markets, sells and distributes its medical device
products.  There are various federal and state healthcare laws and regulations that impose restrictions that may apply to Viveve, and there
may also be comparable foreign laws and regulations that similarly could apply to the Company.

The federal  healthcare  anti-kickback  statute  prohibits,  among  other  things,  persons  from  knowingly  and  willfully  soliciting,
offering,  receiving  or  providing  remuneration,  directly  or  indirectly,  in  cash  or  in  kind,  to  induce  or  reward  either  the  referral  of  an
individual for, or the purchase, order or recommendation of, any good or service, for which payment may be made under federally funded
healthcare  programs.    This  statute  has  been  broadly  interpreted  to  apply  to  manufacturer  arrangements  with  prescribers  and  purchasers,
among  others.    There  are  similar  laws  at  the  state  level  in  the  U.S.,  and  several  other  countries,  including  the  United  Kingdom,  have
enacted similar anti-kickback, fraud and abuse, and healthcare laws and regulations.

The  federal  Health  Insurance  Portability  and Accountability Act  of  1996,  or  HIPAA,  as  amended  by  the  Health  Information
Technology for Economic and Clinical Health Act, imposes criminal and civil liability for executing a scheme to defraud any healthcare
benefit program and also imposes obligations, including mandatory contractual terms, with respect to safeguarding the privacy, security
and  transmission  of  individually  identifiable  health  information.    HIPAA  also  imposes  criminal  liability  for  knowingly  and  willfully
falsifying,  concealing  or  covering  up  a  material  fact  or  making  any  materially  false  statement  in  connection  with  the  delivery  of  or
payment for healthcare benefits, items or services.

The federal Physician Sunshine Act requirements under the Patient Protection and Affordable Care Act of 2010, as amended by
the  Health  Care  and  Education  Reconciliation Act  of  2010,  referred  to  together  as  the Affordable  Care Act,  require  manufacturers  of
drugs, devices, biologics and medical supplies for which payment is available under title XVIII of the Social Security Act [Medicare] or
under  a  State  plan  under  title  XIX  [Medicaid]  or  XXI  [SCHIP]  of  the  Social  Security Act  (or  a  waiver  of  such  a  plan)  to  report  to  the
Department  of  Health  and  Human  Services  information  related  to  payments  and  other  transfers  of  value  made  to  or  at  the  request  of
covered recipients, such as physicians and teaching hospitals, and physician ownership and investment interests in such manufacturers. 
Payments made to physicians and research institutions for clinical trials are included within the scope of this federal disclosure law. 

Analogous  state  laws  and  regulations,  such  as  state  anti-kickback  and  false  claims  laws,  may  apply  to  sales  or  marketing
arrangements  and  claims  involving  healthcare  items  or  services  reimbursed  by  nongovernmental  third-party  payors,  including  private
insurers.    Some  state  laws  also  require  pharmaceutical  and  medical  device  companies  to  comply  with  the  relevant  industry’s  voluntary
compliance guidelines, in addition to requiring manufacturers to report information related to payments to physicians and other health care
providers or marketing expenditures.  There may also be comparable foreign laws and regulations that could impact Viveve’s business and
operations. 

If Viveve’s operations are found to be in violation of any of these laws or any other governmental regulations that may apply to
it,  the  Company  may  be  subject  to  significant  civil,  criminal  and  administrative  penalties,  damages,  or  fines.    Moreover,  if  any  of  the
physicians or other providers or entities with whom Viveve expects to do business are found to be not in compliance with applicable laws,
they may be subject to criminal, civil or administrative sanctions, or potentially to other sanctions in foreign jurisdictions. 

38

 
 
 
 
 
  
 
 
 
 Risks Related to Our Intellectual Property

Intellectual  property  rights  may  not  provide  adequate  protection  for  the  Viveve  System ,  which  may  permit  third  parties  to  compete
against us more effectively.

 We  rely  on  patent,  copyright,  trade  secret  and  trademark  laws  and  confidentiality  agreements  to  protect  our  technology  and
Geneveve  treatment.  We  have  an  exclusive  license  to  or  own  4  issued  U.S.  patents  primarily  covering  our  technology  and  Geneveve
treatment and methods of use. Additionally, we have 8 pending U.S. patent applications; 56 issued foreign patents; and 23 pending foreign
patent applications, some of which foreign applications preserve an opportunity to pursue patent rights in multiple countries. Some of the
Viveve System’s components are not, and in the future may not be, protected by patents. Additionally, our patent applications may not
issue as patents or, if issued, may not issue in a form that will be advantageous to us. Any patents we obtain may be challenged, invalidated
or  legally  circumvented  by  third  parties.  Consequently,  competitors  could  market  products  and  use  manufacturing  processes  that  are
substantially similar to, or superior to, ours. We may not be able to prevent the unauthorized disclosure or use of our technical knowledge
or other trade secrets by consultants, vendors, former employees or current employees, despite the existence generally of confidentiality
agreements and other contractual restrictions. Monitoring unauthorized uses and disclosures of our intellectual property is difficult, and we
do not know whether the steps we have taken to protect our intellectual property will be effective. Moreover, we do not have patent rights
in  all  foreign  countries  in  which  a  market  may  exist,  and  where  we  have  applied  for  foreign  patent  rights,  the  laws  of  many  foreign
countries may not protect our intellectual property rights to the same extent as the laws of the U.S.

 In addition, competitors could purchase the Viveve System and attempt to replicate some or all of the competitive advantages we
derive from our development efforts, willfully infringe our intellectual property rights, design around our protected technology or develop
their  own  competitive  technologies  that  fall  outside  of  our  intellectual  property  rights.  If  our  intellectual  property  is  not  adequately
protected so as to defend our market against competitors’ products and methods, our competitive position and business could be adversely
affected.

We  are  currently  involved  in  and  may  be  involved  in  future  costly  intellectual  property  litigation,  which  could  impact  our  future
business and financial performance.

Our  industry  has  been  characterized  by  frequent  intellectual  property  litigation.  Our  competitors  or  other  patent  holders  may
assert that our device and the methods we employ are covered by their patents. If our device or methods are found to infringe, we could be
prevented from marketing the Viveve System. In addition, we do not know whether our competitors or potential competitors have applied
for, or will apply for or obtain, patents that will prevent, limit or interfere with our ability to make, use, sell, import or export the Viveve
System.  We  may  also  initiate  litigation  against  third  parties  to  protect  our  intellectual  property  that  may  be  expensive,  protracted  or
unsuccessful.  In  the  future  there  may  be  companies  that  market  products  for  competing  purposes  in  direct  challenge  to  our  intellectual
property  position,  and  we  may  be  required  to  initiate  litigation  in  order  to  stop  them.  For  example,  in  October  2016  we  filed  a  patent
infringement lawsuit against ThermiGen, LLC, ThermiAesthetics, LLC and Dr. Red Alinsod alleging unauthorized use of certain of our
patented technologies. based on Viveve’s U.S. Patent Number 8,961,511 (the “‘511 patent”).  Viveve, Inc. v. ThermiGen, LLC et al., No.
2:16-cv-1189-JRG (E.D.Tx.), filed October 16, 2016. We are  seeking an injunction and damages. Especially when asserting our rights, we
run the risk of having our patents invalidated, which would undermine our competitive position. As part of the patent infringement lawsuit
the  defendants’  counterclaims  challenge  the  validity  of  the  ‘511  patent  claims. On October 20, 2017, ThermiGen and ThermiAesthetics
filed  two  petitions  for inter partes  review  (IPR)  of  the  ‘511  patent  at  the  U.S.  Patent  Trial  and Appeal  Board  (PTAB)  challenging  the
validity of the ‘511 patent claims. ThermiGen, LLC et al. v. Viveve, Inc. , No. IPR2018-00088 (October 20, 2017) and ThermiGen, LLC et
al. v. Viveve, Inc., No. IPR2018-00089 (October 20, 2017).

 Litigation related to infringement and other intellectual property claims, with or without merit, is unpredictable, can be expensive
and time-consuming and could divert management’s attention from our business. If we lose this kind of litigation, a court could require us
to pay substantial damages, and prohibit us from using technologies essential to the Viveve System and Geneveve treatment, any of which
would have a material adverse effect on our business, results of operations and financial condition. In that event, we do not know whether
necessary  licenses  would  be  available  to  us  on  satisfactory  terms,  or  whether  we  could  redesign  Geneveve  or  processes  to  avoid
infringement.

 Competing products may also appear in other countries in which our patent coverage might not exist or be as strong. If we lose a

foreign patent lawsuit, we could be prevented from marketing Geneveve in one or more countries.

39

 
 
 
 
 
 
 
 
 
 
 In addition, we may hereafter become involved in litigation to protect our trademark rights associated with our device name or
treatment name. Names used may be claimed to infringe names held by others or to be ineligible for proprietary protection. If we have to
change the name of the company, device or treatment, we may experience a loss in goodwill associated with our brand name, customer
confusion and a loss of sales.

Risks Related to our Securities

Public company compliance may make it more difficult to attract and retain officers and directors.

The Sarbanes-Oxley Act and rules implemented by the Securities and Exchange Commission have required changes in corporate
governance practices  of  public  companies. As  a  public  company,  these  rules  and  regulations  increase  our  compliance  costs  and  make
certain activities more time consuming and costly. These rules and regulations may also make it more difficult and expensive for us to
maintain  our  director  and  officer  liability  insurance  and  we  may  be  required  to  accept  reduced  policy  limits  and  coverage  or  incur
substantially higher costs to obtain the same or similar coverage. As a result, it may be more difficult for us to attract and retain qualified
persons to serve on our board of directors or as executive officers, and to maintain insurance at reasonable rates, or at all.

Concentration of ownership of our common stock may have the effect of delaying or preventing a change in control.

As of March 8, 2018, our officers, directors and principal stockholders, i.e., stockholders who beneficially own greater than 10%
of our outstanding common stock, collectively beneficially own approximately [__] % of our outstanding common stock. As a result, these
stockholders,  if  they  act  together,  will  be  able  to  control  the  management  and  affairs  of  our  company  and  most  matters  requiring
stockholder  approval,  including  the  election  of  directors  and  approval  of  significant  corporate  transactions.  This  concentration  of
ownership may have the effect of delaying or preventing a change in control and might adversely affect the market price of our common
stock. This concentration of ownership may not be in the best interests of our other stockholders.

We  are  a  h olding  company  with  no  business  operations  of  our  own  and  we  depend  on  cash  flow  from  Viveve,  Inc.  to  meet  our
obligations.

 We are a holding company with no business operations of our own or material assets other than the stock we own in Viveve, Inc.
All  of  our  operations  are  conducted  by  Viveve,  Inc. As  a  holding  company,  we  will  require  dividends  and  other  payments  from  our
subsidiary  to  meet  cash  requirements.  The  terms  of  any  agreements  governing  indebtedness  that  we  may  enter  into  may  restrict  our
subsidiary  from  paying  dividends  and  otherwise  transferring  cash  or  other  assets  to  us.  If  there  is  an  insolvency,  liquidation  or  other
reorganization of our subsidiary, our stockholders likely will have no right to proceed against its assets. Creditors of our subsidiary will be
entitled to payment in full from the sale or other disposal of the assets of our subsidiary before we, as an equity holder, would be entitled to
receive any distribution from that sale or disposal. If Viveve, Inc. is unable to pay dividends or make other payments to us when needed,
we will be unable to satisfy our obligations.

Our stock price may be volatile.

 The market price of our common stock is likely to be highly volatile and could fluctuate widely in price in response to various

factors, many of which are beyond our control, including the following:

● actual or anticipated fluctuations in our quarterly financial results or the quarterly financial results of companies perceived to

be similar to us;

● changes in the market’s expectations about our operating results;
● success of competitors;
● our operating results failing to meet the expectations of securities analysts or investors in a particular period;

40

 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
● changes in financial estimates and recommendations by securities analysts concerning our business, the market for our

products, the health services industry, or the healthcare and health insurance industries in general;
● operating and stock price performance of other companies that investors deem comparable to us;
● our ability to market new and enhanced products on a timely basis;
● changes in laws and regulations affecting our business;
● commencement of, or involvement in, litigation involving us;
● changes in our capital structure, such as future issuances of securities or the incurrence of debt;
● the volume of shares of our common stock available for public sale;
● any major change in our board of directors or management;
● sales of substantial amounts of common stock by our directors, executive officers or significant stockholders or the

perception that such sales could occur; and

● general economic and political conditions such as recessions, fluctuations in interest rates and international currency

fluctuations.

In addition, the securities markets have from time to time experienced significant price and volume fluctuations that are unrelated
to the operating performance of particular companies. These market fluctuations may also materially and adversely affect the market price
of our common stock.

Our shares of common stock are thinly traded, the price may not reflect our value, and there can be no assurance that there will be an
active market for our shares of common stock either now or in the future.

 Our shares of common stock are thinly traded, our common stock is held by a small number of holders, and the price may not
reflect our actual or perceived value. There can be no assurance that there will be an active market for our shares of common stock either
now or in the future. The market liquidity will be dependent on the perception of our operating business, among other things. We will take
certain  steps  including  utilizing  investor  awareness  campaigns,  investor  relations  firms,  press  releases,  road  shows  and  conferences  to
increase awareness of our business. Any steps that we might take to bring us to the awareness of investors may require that we compensate
consultants with cash and/or stock. There can be no assurance that there will be any awareness generated or the results of any efforts will
result in any impact on our trading volume. Consequently, investors may not be able to liquidate their investment or liquidate it at a price
that reflects the value of the business, and trading may be at a depressed price relative to the performance of the Company due to, among
other things, the availability of sellers of our shares. If an active market should develop, the price may be highly volatile. Because there is
currently  a  relatively  low  per-share  price  for  our  common  stock,  many  brokerage  firms  or  clearing  firms  are  not  willing  to  effect
transactions in the securities or accept our shares for deposit in an account. Many lending institutions will not permit the use of low priced
shares of common stock as collateral for any loans.

Offers  or  availability  for  sale  of  a  substantial  number  of  shares  of  our  common  stock  may  cause  the  price  of  our  common  stock  to
decline.

 If  our  stockholders  sell  substantial  amounts  of  our  common  stock  in  the  public  market  upon  the  expiration  of  any  statutory
holding  period  under  Rule  144,  or  shares  issued  upon  the  exercise  of  outstanding  options  or  warrants,  it  could  create  a  circumstance
commonly referred to as an “overhang” and, in anticipation of which, the market price of our common stock could fall. The existence of an
overhang,  whether  or  not  sales  have  occurred  or  are  occurring,  also  could  make  more  difficult  our  ability  to  raise  additional  financing
through the sale of equity or equity-related securities in the future at a time and price that we deem reasonable or appropriate.

 In general, under Rule 144, a non-affiliated person who has held restricted shares of our common stock for a period of six months

may sell into the market all of their shares, subject to the Company being current in our periodic reports filed with the Commission.

  As  of  March  8,  2018,  there  were  approximately  1,408,008  shares  of  common  stock  of  the  31,233,972  shares  issued  and
outstanding  that  could  be  sold  pursuant  to  Rule  144,  10,000  shares  of  restricted  stock,  642,622  shares  subject  to  outstanding  warrants,
2,694,224 shares subject to outstanding options and an additional 382,106 shares reserved for future issuance under our 2013 Employee
Stock Option and Incentive Plan, as amended, all of which will become eligible for sale in the public market to the extent permitted by any
applicable vesting requirements or Rule 144 under the Securities Act.

41

 
 
 
 
 
 
 
 
 
 
 
 
  
  
 
 
 
 
 
 
We do not expect to declare or pay dividends in the foreseeable future.

 We have never paid cash dividends on our common stock and have no plans to do so in the foreseeable future.  We  intend  to

retain any earnings to develop, carry on, and expand our business.

Item 1B. Unresolved Staff Comments

None

Item 2. Properties

In  January  2012,  we  entered  into  a  lease  agreement  for  office  and  laboratory  facilities  in  Sunnyvale,  California. The  space
consists of approximately 7,777 square feet. The term of the lease agreement, dated January 25, 2012, as amended in January 2015 and
September 2016, commenced in March 2012 and will terminate on March 31, 2018. 

On February 1, 2017, we entered into a Sublease for approximately 12,400 square feet of building space for the relocation of the
Company’s corporate headquarters to Englewood, Colorado. The lease term is 36 months. The lease term commenced on June 1, 2017 and
will terminate in May 2020. We believe that these facilities are adequate for our current business operations.

Rent  expense  for  the  years  ended  December  31,  2017  and  2016  was  $442,000  and  $236,000,  respectively.  Future  minimum

payments under the lease are approximately as follows:

Year Ending December
31,

2018 – $338,000
2019 – $264,000
2020 – $112,000

Item 3. Legal Proceedings

On March 11, 2016, the Company filed a demand for Arbitration with the American Arbitration Association ("AAA") against a
former employee asserting common law and statutory negligence claims against the former employee arising from the former employee's
negligent performance of certain work duties. The demand seeks damages for lost profits, along with attorney's fees, interest, and costs.
 The former employee filed a counterclaim in the proceeding, alleging discrimination, retaliation, wrongful termination, and various claims
for  alleged  wage  and  hour  violations  under  the  California  Labor  Code,  stemming  from  the  cessation  of  her  employment  with  the
Company.    The  former  employee  seeks  damages  for  lost  wages,  punitive  damages,  statutory  penalties,  injunctive  relief,  and  attorney’s
fees, interest and costs.

On October 21, 2016, Viveve filed a lawsuit against ThermiGen LLC, ThermiAesthetics LLC, and Dr. Alinsod, in the Eastern
District of Texas alleging infringement of Viveve’s U.S. Patent Number 8,961,511 (the “‘511 patent”).  The lawsuit alleges infringement
based on Defendants use and/or sale of the ThermiVa system and ThermiVa procedure.  Viveve is seeking an injunction and damages. 

 On October 20, 2017, ThermiGen and ThermiAesthetics filed two petitions for inter partes review (IPR) of the ‘511 patent at the
U.S. Patent Trial and Appeal Board (PTAB).  The IPR petitions challenge the validity of the ‘511 patent claims as allegedly anticipated
and obvious in view of prior patents and publications. 

Item 4. Mine Safety Disclosures

Not applicable.

42

 
 
 
 
 
  
 
 
 
 
 
 
 
   
 
 
 
 
  
 
 
 
 
 
 
 
PART II

Item 5. Market for Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities

As of March 8, 2018, our common stock is trading on The Nasdaq Capital Market under the symbol “VIVE”. Prior to June 14,
2016, our common stock traded on the OTCQB of the OTC Markets Group Inc. under the symbol VIVMF, and prior to October 22, 2014,
our common stock traded under the symbol “PLCSF” and “PLCSD”.

The following  table  sets  forth,  (i)  for  the  periods  during  which  the  Company  was  listed  on  the  OTCQB,  the  high  and  low  bid
prices for our common stock for the periods indicated as reported by the OTCQB, and (ii) for the periods during which the Company has
been  listed  on  The  Nasdaq  Capital  Market,  the  high  and  low  sales  price  for  the  periods  indicated  as  reported  by  The  Nasdaq  Capital
Market.  The  bid  quotations  reported  by  the  OTCQB  reflect  inter-dealer  prices,  without  retail  mark-up,  mark-down  or  commission,  and
may not represent actual transactions. The bid quotations reflect a one-for-100 reverse stock split we effected on September 23, 2014.

Period (Listed on The Nasdaq Capital Market)
October 1, 2017 through December 31, 2017
July 1, 2017 through September 30, 2017
April 1, 2017 through June 30, 2017
January 1, 2017 through March 31, 2017

October 1, 2016 through December 31, 2016
July 1, 2016 through September 30, 2016
June 14, 2016 through June 30, 2016

Period (Listed on the OTCQB)
April 1, 2016 through June 13, 2016
January 1, 2016 through March 31, 2016

High

Low

5.96    $
7.73    $
11.16    $
6.75    $

7.99    $
10.00    $
5.14    $

High

Low

9.00    $
6.80    $

4.30 
4.87 
5.51 
3.75 

4.38 
4.10 
4.02 

1.01 
4.80 

  $
  $
  $
  $

  $
  $
  $

  $
  $

The last reported closing price of our common stock on The  Nasdaq Capital Market on March 8, 2018 was $4.10 per share.

Holders

As of March 8, 2018, there were 605 holders of record of our common stock.

Dividends

We have not declared or paid any cash dividends on our common stock, and we currently intend to retain future earnings, if any,
to finance the expansion of our business; we do not expect to pay any cash dividends in the foreseeable future. The decision whether to pay
cash dividends on our common stock will be made by our board of directors, in their discretion, and will depend on our financial condition,
results of operations, capital requirements and other factors that our board of directors considers significant.

Securities Authorized For Issuance Under Equity Compensation Plans

The  Company  has issued equity awards in the form of stock options from three employee benefit plans. The plans include the
Company’s 2005 Stock Incentive Plan (the “2005 Plan”), the Viveve Amended and Restated 2006 Stock Plan (the “2006 Plan”) and the
Company’s Amended and Restated 2013 Stock Option and Incentive Plan (the “2013 Plan”).

43

 
 
 
 
 
   
 
   
 
 
     
       
 
 
 
   
 
 
 
 
 
 
 
 
  
The following table sets forth information about the 2005 Plan, the 2006 Plan and the 2013 Plan as of December 31, 2017:

Plan Category
Equity compensation plans approved by security holders (2005 Plan)
Equity compensation plans approved by security holders (2006 Plan)
Equity compensation plans not approved by security holders (2013 Plan)
Total

Number of
securities
to be issued
upon
exercise of
outstanding
options,
warrants and
rights

Weighted
average
exercise
price of
outstanding
options,
warrants
and rights

Number of
securities
remaining
available for
future
issuance under
equity
compensation
plans

-    $
38,378    $
2,655,846    $
2,694,224     

-     
10.49     
5.73     

- 
- 
1,186,527 
1,186,527 

The  2006  Plan  was  adopted  by  the  board  of  directors  of  Viveve  and  was  terminated  in  conjunction  with  the  Merger.
Outstanding stock option awards have been assumed by Viveve Medical and will continue to be administered in accordance with the terms
of the 2006 Plan until such awards are exercised, expire, terminate or are forfeited. There are currently outstanding stock option awards
issued from the 2006 Plan covering a total of 38,378 shares of our common stock and no shares available for future awards. The weighted
average exercise price of the outstanding stock options is $10.49 per share and the weighted average remaining contractual term is 4.88
years. Additionally, prior to the Merger, the board of directors voted to accelerate the vesting of all unvested options that were outstanding
as of the date of the Merger such that all options would be immediately vested and exercisable by the holders. Furthermore, at the Merger,
outstanding options to purchase shares of Viveve, Inc. common stock issued from the 2006 Plan were converted into options to purchase
shares of Viveve Medical common stock (rounded down to the nearest whole share). The number of shares of Viveve Medical common
stock into which the 2006 Plan options were converted was determined by multiplying the number of shares covered by each 2006 Plan
option by the exchange ratio of 0.0080497. The exercise price of each 2006 Plan option was determined by dividing the exercise price of
each 2006 Plan option immediately prior to the Merger by the exchange ratio of 0.0080497 (rounded up to the nearest cent).

 On August 22, 2016, the Company’s stockholders approved an amendment to the 2013 Plan to add an “evergreen” provision
which will automatically increase annually, on the first day of each January, the maximum number of shares of common stock reserved
and available under the 2013 plan (the “Stock Issuable”) by an amount equal to the lesser of (i) the number of shares that will increase the
Stock Issuable by 4% of the total number of shares of common stock outstanding (on a fully diluted basis) or (ii) an amount determined by
the board of directors. On December 23, 2016, the board of directors approved the 2017 evergreen increasing the total stock reserved for
issuance under the 2013 Plan by 523,209 shares from 2,000,000 shares to a total of 2,523,209 shares, which was effective January 1, 2017.
On August 15, 2017, the Company’s stockholders approved an amendment to the 2013 Plan increasing the number of shares of common
stock authorized for awards under the 2013 Plan from 2,523,209 shares to a total of 4,000,000 shares. On December 6, 2017, the board of
directors  approved  the  2018  evergreen  increasing  the  total  stock  reserved  for  issuance  under  the  2013  Plan  by  780,143  shares
from 4,000,000 shares to a total of 4,780,143 shares, which was effective January 1, 2018.

Issuances of Unregistered Securities

Not applicable.

44

 
 
 
 
   
   
 
   
   
   
   
      
 
 
 
 
 
Item 6. Selected Financial Data

As a "smaller reporting company" as defined by Item 10 of Regulation S-K, the Company is not required to provide information

required by this Item.

Item 7. Management's Discussion and Analysis of Financial Condition and Results of Operations

 Forward-Looking Statements

This report contains forward-looking statements that involve risks and uncertainties. These statements relate to future events or
our future financial performance. In some cases, you can identify forward-looking statements by terminology including, "could" "may",
"will",  "should",  "expect",  "plan",  "anticipate",  "believe",  "estimate",  "predict",  "potential"  and  the  negative  of  these  terms  or  other
comparable terminology. These statements are only predictions. Actual events or results may differ materially.

While these forward-looking statements, and any assumptions upon which they are based, are made in good faith and reflect our
current judgment regarding the direction of our business, actual results will almost always vary, sometimes materially, from any estimates,
predictions, projections, assumptions or other future performance suggested in this Annual Report.

The following discussion should be read in conjunction with the consolidated financial statements and the related notes contained
elsewhere in this Annual Report. In addition to historical information, the following discussion contains forward looking statements based
upon current expectations that are subject to risks and uncertainties. Actual results may differ substantially from those referred to herein
due to a number of factors, including, but not limited to, risks described in the section entitled “Risk Factors”.

Overview of Our Business

In the discussion below, when we use the terms “ we”, “us” and “our”, we are referring to Viveve Medical, Inc. and our wholly-

owned subsidiaries, Viveve, Inc. and Viveve BV.

We  design,  develop,  manufacture  and  market  a platform  medical  technology,  which  we  refer  to  as Cryogen-cooled  Monopolar
Radiofrequency, or CMRF. Our proprietary CMRF technology is delivered through a radiofrequency generator, handpiece and treatment
tip that, collectively, we refer to as the Viveve® System. The Viveve System is currently used for a number of indications, depending on
the relevant country-specific clearance or approval, in a procedure we refer to as the Geneveve treatment. Currently, the Viveve System is
cleared for marketing in 62 countries throughout the world under the following indications for use: 

 Indication for Use:

 General Surgical procedures for electrocoagulation and hemostasis

 For treatment of vaginal laxity
 For treatment of the vaginal introitus, after vaginal childbirth, to improve sexual function
 For vaginal rejuvenation

  No. of Countries:  
 (including the
U.S.)

  3

  41
  17
  1

In the U.S., the Viveve System is indicated for use in  general surgical procedures for electrocoagulation and hemostasis and we
market and sell primarily through a direct sales force. Outside the U.S., we market and sell through distribution partners. As of December
31, 2017, we have sold 444 Viveve Systems and approximately 14,875 single-use treatment tips.

Because the revenues we have earned to date have not been sufficient to support our operations, we have relied on sales of our
securities, bank term loans and loans from related parties to fund our operations. We relocated the corporate headquarters from Sunnyvale,
California to Englewood, Colorado in June 2017 as discussed below in “Recent Events.”

45

 
 
 
  
 
 
  
 
 
 
 
 
 
  
  
  
 
 
 
We are subject to risks, expenses and uncertainties frequently encountered by companies in the medical device industry. These
risks include, but are not limited to, intense competition, whether we can be successful in obtaining U.S. Food and Drug Administration
(the “FDA”) clearance or approval for the sale of our product and whether there will be a demand for the Geneveve treatment, given that
the cost of the procedure will likely not be reimbursed by the government or private health insurers. In addition, we will continue to require
substantial funds to support our clinical trials and fund our efforts to expand regulatory clearance or approval for our products in locations
in which we do not currently have clearance or approval to market our product, including the U.S. We cannot be certain that any additional
required financing will be available when needed or on terms which are favorable to us. As noted above, our operations to date have been
primarily funded through the sales of our securities, bank term loans and loans from related parties. Various factors, including our limited
operating history with minimal revenues to date and our limited ability to market and sell our product have resulted in limited working
capital available to fund our operations. There are no assurances that we will be successful in securing additional financing in the future to
fund  our  operations  going  forward.  Failure  to  generate  sufficient  cash  flows  from  operations,  raise  additional  capital  or  reduce  certain
discretionary spending could have a material adverse effect on our ability to achieve our intended business objectives.  

Recent Events

Sublease 

On February 1, 2017, the Company entered into a sublease agreement (the “ Sublease”) for approximately 12,400 square feet of
building space for the relocation of the Company’s corporate headquarters to Englewood, Colorado (the “Sublease Premises”), which is
effective as of January 26, 2017. The lease term commenced on June 1, 2017 and will terminate in May 2020. We relocated our corporate
headquarters from Sunnyvale, California to Englewood, Colorado in June 2017.

The monthly base rent under the Sublease is equal to $20.50 per rentable square foot of the Sublease Premises during the first
year. The monthly base rent will be equal to $21.12 and $21.75 per rentable square foot during the second and third years, respectively. In
connection  with  the  execution  of  the  Sublease,  the  Company  also  agreed  to  pay  a  security  deposit  of  approximately  $22,000.  The
Company  is  entitled  to  an  allowance  of  approximately  $88,000  for  certain  tenant  improvements  relating  to  the  engineering,  design  and
construction of the Sublease Premises.

March 2017 Offering

On  March  22,  2017,  in  connection  with  the  closing  of  a  public  offering  (the  “March  2017  Offering”),  the  Company  issued  an
aggregate  of  8,625,000  shares  of  common  stock,  including  the  shares  issued  in  connection  with  the  exercise  of  the  underwriters’
overallotment option, at a public offering price of $4.00 per share for gross proceeds of approximately $34,500,000. The net proceeds to
the Company, after the deduction of underwriting discounts, commissions and other offering expenses, were approximately $31,440,000.

Loan Agreement

On May 22, 2017, the Company entered into a Term Loan Agreement (the “ 2017 Loan Agreement”) with affiliates of CRG LP
(“CRG”).  The  credit  facility  consists  of  $20,000,000  drawn  at  closing  and  access  to  additional  funding  of  up  to  an  aggregate  of
$10,000,000 for a total of $30,000,000 available under the credit facility. On December 29, 2017, the Company accessed the remaining
$10,000,000 available under the CRG credit facility.

A portion of the initial loan proceeds were used to repay all of the amounts  owed by the Company under its existing Loan and
Security Agreement, as amended January 13, 2017 (the “2016 Loan Agreement”) with Western Alliance Bank. The remainder of the loan
proceeds (after deducting loan origination costs and other fees and expenses incurred in connection with the 2017 Loan Agreement) will
be used for general corporate purposes and working capital.

The  2017  Loan Agreement  has  a  six-year  term  with  four  years  of  interest-only  payments  after  which  quarterly  principal  and
interest payments will be due through the maturity date. Amounts borrowed under the 2017 Loan Agreement accrue interest at an annual
fixed rate of 12.50%, 4.0% of which may, at the election of the Company, be paid in-kind during the interest-only period by adding such
accrued amount to the principal loan amount each quarter. During the year ended December 31, 2017, the Company paid interest in-kind
of $495,000 which was added to the total outstanding principal loan amount as of December 31, 2017. The Company is also required to
pay CRG a final payment fee upon repayment of the loans in full.

46

 
 
 
 
 
 
 
 
 
 
 
 
 
The  Company  may  prepay  all  or  a  portion  of  the  outstanding  principal  and  accrued  unpaid  interest  under  the  2017  Loan
Agreement at any time upon prior notice to CRG, subject to a prepayment fee during the first five years of the term (which reduces each
year) and no prepayment fee thereafter.

As  security  for  its  obligations  under  the  2017  Loan  Agreement,  the  Company  entered  into  security  agreements  with  CRG

whereby the Company granted CRG a lien on substantially all of the Company’s assets, including intellectual property.

The terms of the 2017 Loan Agreement also require the Company to meet certain financial and other covenants. These covenants
require the Company to maintain cash and cash equivalents of $2.0 million and, each year through the end of 2022, to meet a minimum
total annual revenue threshold. In the event that the Company does not meet the minimum total annual revenue threshold for a particular
year,  the  Company  can  retroactively  cure  the  shortfall  by  either  issuing  additional  equity  in  exchange  for  cash  or  incurring  certain
additional permitted indebtedness, in each case, in an amount equal to 2.0 times the shortfall. Any such amounts shall be applied to prepay
the loans. The 2017 Loan Agreement also contains customary affirmative and negative covenants for a credit facility of this size and type,
including  covenants  that  limit  or  restrict  the  Company’s  ability  to,  among  other  things,  incur  indebtedness,  grant  liens,  merge  or
consolidate,  dispose  of  assets,  make  investments,  make  acquisitions,  enter  into  transactions  with  affiliates,  pay  dividends  or  make
distributions, license intellectual property rights on an exclusive basis or repurchase stock, in each case subject to customary exceptions. As
of December 31, 2017, the Company was in compliance with all covenants.

In connection with the 2017 Loan Agreement, the Company issued two 10-year warrants to CRG to purchase a total of 222,049

shares of the Company’s common stock at an exercise price of $9.50 per share. 

2017 Employee Stock Purchase Plan

At the Company’s annual meeting of the stockholders held on August 15, 2017, the stockholders approved the Company’s 2017
Employee  Stock  Purchase  Plan  (the  “2017  ESPP”).  It  is  the  Company’s  intention  that  the  2017  ESPP  qualify  as  an  “employee  stock
purchase plan” under Section 423 of the Internal Revenue Code.

Shares Subject to the Plan. An aggregate of 400,000 shares has been reserved and available for issuance under the 2017 ESPP.

Plan Administration. The 2017 ESPP is administered by the compensation committee of the board of directors.

Eligibility.  Employees  of  the  Company  and  its  U.S.  subsidiary  are  eligible  to  participate  in  the  2017  ESPP  so  long  as  the
employee  is  employed  for  more  than  20  hours  a  week  and  has  completed  at  least  six  months  of  employment  on  the  first  day  of  the
applicable offering period. No person who owns or holds, or as a result of participation in the 2017 ESPP would own or hold, common
stock or options to purchase common stock, that together equal to 5% or more of total outstanding common stock is entitled to participate
in  the  2017  ESPP.  No  employee  may  exercise  an  option  granted  under  the  2017  ESPP  that  permits  the  employee  to  purchase  common
stock of the Company having a value of more than $25,000 (determined using the fair market value of the stock at the time such option is
granted) in any calendar year.  

Participation and Payroll Deductions. Participation in the 2017 ESPP is limited to eligible employees. Eligible employees may
authorize payroll deductions, with a minimum of 1% of base pay and a maximum of 15% of base pay. There are currently approximately
40  employees  who  will  be  eligible  to  participate  in  the  2017  ESPP.  Once  an  employee  becomes  a  participant  in  the  2017  ESPP,  that
employee will automatically participate in successive offering periods until such time as that employee withdraws from the 2017 ESPP,
becomes ineligible to participate in the 2017 ESPP, or his or her employment ceases.  

47

 
 
 
 
 
 
 
 
 
 
 
 
Offering Periods. Each offering of common stock under the 2017 ESPP is for a period of three months, which is referred to as the
“offering  period.”  The  first  offering  period  under  the  2017  ESPP  began  on  October  1,  2017  and  will  end  on  December  31,  2017.
Subsequent offerings under the 2017 ESPP will generally begin on the first business day occurring on or after each January 1st, April 1st,
July 1st and October 1st and will end on the last business day occurring on or before the following March 31st, June 30th, September 30th
and December 31st, respectively. Shares are purchased on the last business day of each offering period, with that day being referred to as
an “exercise date.”  

Exercise Price. On the first day of an offering period, employees participating in that offering period will receive an option to
purchase shares of our common stock. On the exercise date of each offering period, the employee is deemed to have exercised the option,
at the exercise price, to the extent of accumulated payroll deductions. The option exercise price is equal to the lesser of (i) 85% the fair
market value per share of our common stock on the first day of the offering period or (ii) 85% of the fair market value per share of our
common stock on the exercise date. The maximum number of shares of common stock that may be issued to any employee under the 2017
ESPP  in  any  offering  period  is  2,000.  If  an  employee  is  no  longer  a  participant  on  an  exercise  date,  the  employee’s  option  will  be
automatically terminated, and the amount of the employee’s accumulated payroll deductions will be refunded.  

Terms of Participation. A participant may not increase or decrease the amount of his or her payroll deductions during any offering
period but may increase or decrease his or her payroll deduction with respect to the next offering period by completing a new enrollment
form within the period beginning on the first day of the month before the first day of such offering period and ending on the 14th day of
the month before the first day of such offering period. A participant may withdraw from an offering period at any time without affecting
his or her eligibility to participate in future offering periods. If a participant withdraws from an offering period, that participant may not
again participate in the same offering period, but may enroll in subsequent offering periods. An employee’s withdrawal will be effective as
of the business day following the employee’s delivery of written notice of withdrawal under the 2017 ESPP.  

Term; Amendments and Termination. The 2017 ESPP will continue until terminated by the board of directors. Upon termination

of the 2017 ESPP, all amounts in the accounts of participating employees will be refunded.  

On August 8, 2017, the Company entered into an exclusive Distributorship Agreeme nt (the “Distributorship Agreement”) with
InControl Medical, LLC (“ICM”), a Wisconsin limited liability company focused on women's health, pursuant to which the Company will
directly  market,  promote,  distribute  and  sell  ICM’s  products  to  licensed  medical  professional  offices  and  hospitals.  The  products  to  be
distributed by the Company include ICM’s InTone™, InToneMV™, ApexM™, and Intensity™ products. 

Under the terms of the Distributorship Agreement, ICM agreed to not directly or indirectly appoint or autho rize any third party to
market, promote, distribute or sell any of the licensed products to any licensed medical professional offices and hospitals in the United
States. In exchange, the Company agreed to not market, promote, distribute or sell (or contract to do so) any product which substantially
replicates all or almost all of the key features of the licensed products. The Company has a minimum purchase requirement to purchase a
certain quantity of ICM products per month during the term of this Distributorship Agreement . In addition, the parties agreed to certain
mutual marketing obligations to promote sales of the licensed products. 

Investment in Limited Liability Company 

In connection with the Distributorship Agreement, the Company also entered into a   Membership  Unit  Subscription Agreement
with ICM and the associated limited liability company operating agreement of ICM, pursuant to which the Company invested $2,500,000
in, and acquired membership units of, ICM. As of December 31, 2017, the Company owns approximately 11% ownership interest in ICM.

48

 
 
 
 
 
 
 
 
 
 
Effective Shelf Registration Statements

In October 2016, we filed a universal shelf registration statement with the SEC on Form S-3 for the proposed offering from time to time of
up to $50,000,000 of our securities, including common stock, preferred stock, and/or warrants. This registration statement currently has a
capacity of $15,500,000. In November 2017, we filed a universal shelf registration statement with the SEC on Form S-3 for the proposed
offering  from  time  to  time  of  up  to  $50,000,000  of  our  securities,  including  common  stock,  preferred  stock,  and/or  warrants.  This
registration statement currently has a capacity of $25,000,000.

“At-the-Market” Offering

The Company established,  through  the  filing  of  a  prospectus  supplement  to  its  shelf  registration  statement  on  Form  S-3  (filed
November 8, 2017), an “at-the-market” equity offering program under which the Company may offer and sell, from time to time, up to
$25,000,000 aggregate offering price of shares of its common stock (the “November 2017 ATM Facility”). As of December 31, 2017, the
Company has sold 59,249 shares of common stock under the November 2017 ATM Facility for net proceeds of approximately $125,000.
In January 2018, the Company sold 208,277 shares of common stock for net proceeds of approximately $1,025,000 under the November
2017 ATM Facility. There have been no other shares sold under the November 2017 ATM Facility through the date of this filing.

February 2018 Offering

On February 12, 2018, in connection with the closing of a public offering, the Company issued an aggregate of 11,500,000 shares
of  common  stock,  including  the  shares  issued  in  connection  with  the  exercise  of  the  underwriters’  overallotment  option,  at  a  public
offering price of $3.00 per share for gross proceeds of approximately $34,500,000. The net proceeds to the Company were approximately
$32,380,000, after deducting underwriting discounts and commissions (but before deducting estimated offering expenses payable by the
Company).   

Plan of Operation

We intend to increase our sales both internationally and in the U.S. market by seeking regulatory clearances or approvals for the
sale and distribution of our products, identifying and training qualified distributors and expanding the scope of physicians who offer the
Geneveve  treatment  to  include  plastic  surgeons,  dermatologists,  general  surgeons,  urologists,  urogynecologists  and  primary  care
physicians.

In addition, we intend to use the strategic relationships that we have developed with outside contractors and medical experts to

improve our products by focusing our research and development efforts on various areas including, but not limited to:

● designing new treatment tips optimized for both ease-of-use and to reduce procedure times for patients and physicians; and
● Developing  new  RF  consoles,  which  may  include  increased  security  features  to  prevent  piracy,  or  new  cooling  systems  to

maintain compliance with environmental regulations.

The  net  proceeds  received  from  sales  of  our  securities  and  the  term  loans  have  been  used  to  support  commercialization  of  our
product in existing and new markets, for our research and development efforts and for protection of our intellectual property, as well as for
working capital and other general corporate purposes. We expect that our cash will be sufficient to fund our activities for at least the next
twelve months, however, we will continue to require funds to fully implement our plan of operation. Our operating costs include employee
salaries  and  benefits,  compensation  paid  to  consultants,  professional  fees  and  expenses,  costs  associated  with  our  clinical  trials,  capital
costs for research and other equipment, costs associated with research and development activities including travel and administration, legal
expenses, sales and marketing costs, general and administrative expenses, and other costs associated with an early stage public company
subject to the reporting requirements of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). We also expect to incur
expenses  related  to  obtaining  regulatory  approvals  in  the  U.S.  and  internationally  as  well  as  legal  and  related  expenses  to  protect  our
intellectual property. We expect capital expenditures, for the foreseeable future, to be less than $500,000 annually.  

49

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 We intend to continue to meet our operating cash flow requirements through the sales of our products and by raising additional
funds from the sale of equity or debt securities. If we sell our equity securities, or securities convertible into equity, to raise capital, our
current  stockholders  will  likely  be  substantially  diluted.  We  may  also  consider  the  sale  of  certain  assets,  or  entering  into  a  strategic
transaction, such as a merger, with a business complimentary to ours, although we do not currently have plans for any such transaction.
While we have been successful in raising capital to fund our operations since inception, other than as discussed in this Annual Report on
Form  10-K,  we  do  not  have  any  committed  sources  of  financing  and  there  are  no  assurances  that  we  will  be  able  to  secure  additional
funding, or if we do secure additional financing that it will be on terms that are favorable to us. If we cannot obtain financing, then we may
be forced to curtail our operations or consider other strategic alternatives. 

Results of Operations

Year Ended December 31, 2017 Compared to the Year Ended December 31, 2016

Revenue

Year Ended
December 31,

Change

2017

2016

$

%

(in thousands, except percentages)

Revenue

  $

15,288    $

7,141    $

8,147     

114%

 We recorded revenue of $15,288,000 for the year ended December 31, 2017 , compared to revenue of $7,141,000 for the year
ended December 31, 2016, an increase of $8,147,000. The increase in revenue was primarily due to sales of 227 Viveve Systems (which
included  160  Viveve  Systems  sold  in  the  U.S.  market  through  direct  sales),  higher  quantities  of  disposable  treatment  tips  and  other
ancillary consumables in 2017. Sales in 2016 included 175 Viveve Systems and smaller quantities of disposable treatment tips and other
ancillary consumables sold primarily outside the U.S. to our distribution partners. 

Gross Profit

Year Ended
December 31,

Change

2017

2016

$

%

(in thousands, except percentages)

Gross profit

  $

7,444    $

2,529    $

4,915     

194%

  Gross  profit  was  $7,444,0000,  or  49%  of  revenue,  for  the  year  ended  December  31,  2017,  compared  to  gross  profit  of
$2,529,000,  or  35%  of  revenue,  for  the  year  ended  December  31,  2016.  The  increase  in  gross  profit  was  primarily  due  to  sales  of  227
Viveve Systems in 2017, which included 160 Viveve Systems sold in the U.S. market through direct sales .  Sales  in  2016  included  175
Viveve Systems and smaller quantities of disposable treatment tips and other ancillary consumables sold primarily outside the U.S. to our
distribution partners.

50

 
 
 
 
 
 
 
 
     
 
     
 
 
 
 
   
 
 
 
   
   
   
 
 
 
 
 
     
       
       
       
 
 
 
 
 
 
     
 
     
 
 
 
 
   
 
 
 
   
   
   
 
 
 
 
 
     
       
       
       
 
 
 
 The  increase  in  gross  margin  was  primarily  due  to  an  increase  in  revenue  from  direct  sales  with  higher  margin  products.  We

expect our gross margin to fluctuate in future periods based on the mix of our product and direct sales versus distributor sales.

Research and development expenses 

Year Ended
December 31,

Change

2017

2016

$

%

(in thousands, except percentages)

Research and development

  $

12,343    $

8,365    $

3,978     

48%

Research  and  development  expenses  totaled $12,343,000  for  the  year  ended  December  31,  2017,  compared  to  research  and
development expenses of $8,365,000 for the year ended December 31, 2016, an increase of $3,978,000, or approximately 48%. Spending
on research and development increased in 2017 primarily due to costs associated with increased engineering and development work with
our contract manufacturer related to product improvement efforts. Research and development expense during 2017 also included higher
personnel costs for new employees and related additional stock-based compensation expense for stock options granted to new employees
and additional stock options granted to existing employees for performance bonuses.  

Selling, general and administrative expenses

Year Ended
December 31,

Change

2017

2016

$

%

(in thousands, except percentages)

Selling, general and administrative

  $

28,831    $

12,868    $

15,963     

124%

Selling, general and administrative expenses totaled $28,831,000 for the year ended December 31, 2017, compared to $12,868,000
for  the  year  ended  December  31,  2016,  an  increase  of  $15,963,000,  or  approximately  124%.  The  increase  in  selling,  general  and
administrative expenses in 2017 was primarily attributable to increased sales and marketing efforts to build brand and market awareness,
expenses  associated  with  being  a  public  company  and  financing  efforts.  Selling,  general  and  administrative  expenses  during  2017  also
included higher personnel costs for new employees (primarily in connection with our sales and marketing efforts) and related additional
stock-based compensation expense for stock options granted to new employees and additional options granted to existing employees for
performance bonuses.

Interest expense 

Year Ended
December 31,

Change

2017

2016

$

%

(in thousands, except percentages)

Interest expense, net

  $

3,169    $

1,370    $

1,799     

131%

 During  the  year  ended  December  31,  2017,  we  had  interest  expense,  net,  of  $3,169,000,  compared  to  $1,370,000  for  the  year
ended December 31, 2016. The increase of $1,799,000, or approximately 131% resulted primarily from the additional interest expense in
connection with the payoff in May 2017 of the previous term loan under the 2016 Loan Agreement, and the additional interest expense
under the 2017 Loan Agreement, which was computed on a higher loan balance compared to the previous term loan under the 2016 Loan
Agreement.

51

 
 
 
 
 
 
     
 
     
 
 
 
 
   
 
 
 
   
   
   
 
 
 
 
 
     
       
       
       
 
 
 
 
 
 
     
 
     
 
 
 
 
   
 
 
 
   
   
   
 
 
 
 
 
     
       
       
       
 
 
 
 
 
 
     
 
       
 
 
 
   
 
 
 
   
   
   
 
 
 
 
 
     
       
       
       
 
 
 
Other income (expense), net

Year Ended
December 31,

Change

2017

2016

$

%

(in thousands, except percentages)

Other expense, net

  $

60    $

37    $

23     

62%

During the year ended December 31, 2017 we had other expense, net, of $60,000 as compared to other expense, net, of $37,000 for

the year ended December 31, 2016.

Liquidity and Capital Resources

Year Ended December 31, 2017

Liquidity is our ability to generate sufficient cash flows from operating activities to meet our obligations  and  commitments.  In
addition, liquidity includes the ability to obtain appropriate financing or to raise capital. We have funded our operations since inception
through the sale of our securities, bank term loans and loans from related parties. To date, we have not generated sufficient cash flows from
operating activities to meet our obligations and commitments, and we anticipate that we will continue to incur losses for the foreseeable
future. We expect that our cash will be sufficient to fund our activities for at least the next twelve months, however, we will continue to
require funds from financing sources to fully implement our plan of operation.

The following table summarizes the primary sources and uses of cash for the periods presented below (in thousands):

Net cash used in operating activities
Net cash used in investing activities
Net cash provided by financing activities
Net increase in cash and cash equivalents

 Operating Activities

Year Ended
December 31,

2017

2016

  $

  $

(34,853)  $
(3,405)   
50,902     
12,644    $

(18,087)
(256)
19,069 
726 

We have incurred, and expect to continue to incur, significant expenses in the areas of research and development, regulatory and

clinical study costs associated with Geneveve.

Operating activities used $34,853,000  for  the  year  ended  December  31,  2017  compared  to  $18,087,000  used  for  the  year  ended
December 31, 2016. The primary use of our cash was to fund selling, general and administrative expenses and research and development
expenses  associated  with  Geneveve.  Net  cash  used  during  the  year  ended  December  31,  2017  consisted  of  a  net  loss  of  $36,959,000
adjusted for non-cash expenses including provision for doubtful accounts of $221,000, depreciation and amortization of $449,000, stock-
based compensation of $1,872,000, fair value of restricted common shares issued of $260,000, non-cash interest expense of $1,049,000
and cash inflows from changes in operating assets and liabilities of $1,303,000. Net cash used during the year ended December 31, 2016
consisted of a net loss of $20,111,000 adjusted for non-cash expenses including depreciation and amortization of $111,000, stock-based
compensation of $981,000, fair value of warrants issued to service providers (primarily related to nonemployee contractors) of $162,000,
a  restricted  stock  award  granted  to  a  consultant  of  $39,000,  non-cash  interest  expense  of  $456,000  and  cash  inflows  from  changes  in
operating assets and liabilities of $275,000.

52

 
 
 
 
 
     
 
       
 
 
 
   
 
 
 
   
   
   
 
 
 
 
 
     
       
       
       
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
   
 
 
     
       
 
   
   
 
 
 
 
Investing Activities

Net  cash  used  in  investing  activities  during the  year  ended  December  31,  2017  and  2016  was  $3,405,000  and  $256,000,
respectively. Net cash used in investing activities during 2017 was used for the $2,500,000 equity investment in ICM and the purchase of
property and equipment. During 2016, net cash used in investing activities was due to the purchase of property and equipment. We expect
to continue to purchase property and equipment in the normal course of our business. The amount and timing of these purchases and the
related cash outflows in future periods is difficult to predict and is dependent on a number of factors including, but not limited to, any
increase in the number of our employees and any changes to the capital equipment requirements related to our development programs and
clinical trials.

Financing Activities

Net cash provided by financing activities during year ended December 31, 2017 was $50,902,000, which was the result of the
gross proceeds of $34,500,000 from our March 2017 Offering (partially offset by transaction costs of $3,060,000),  gross  proceeds  of
$304,000 from our November 2017 ATM Facility (partially offset by transaction cost of $179,000), the debt proceeds of $30,000,000
from the drawdown of funds under the 2017 Loan Agreement (partially offset by debt issuance costs of $790,000), proceeds from shares
purchased  under  the  Company’s  employee  stock  purchase  plan  of  $76,000,  and  proceeds  from  the  exercise  of  stock  options  and  a
warrant of $51,000, partially offset by the repayment of the term loan under the 2016 Loan Agreement of $10,000,000.  

Net cash provided by financing activities during year ended December 31, 2016 was $19,069,000 which was primarily the result
of  the  net  proceeds  of  $13,886,000  from the  closing  of  our  public  offering  in  June  2016,  the  debt  proceeds  of  $10,000,000  from  the
drawdown  of  funds  from  the  first  and  second  tranches  of  the  term  loan  under  the  2016  Loan Agreement  (partially  offset  by  debt
issuance costs of $90,000), and proceeds from the exercise of warrants and stock options of $106,000, partially offset by the repayment
of the term loan under the loan and security agreement entered into in 2014, as amended, of $4,833,000.

Contractual Payment Obligations

We  have  obligations  under  a  non-cancelable  operating  lease  and  a  bank  term  loan. As  of  December  31,  2017,  our  contractual

obligations are as follows (in thousands):

Contractual Obligations:
Non-cancellable operating lease obligations
Debt obligations (including interest)

Total

Total

    Less than      
1 Year

  $

  $

714    $
50,546     
51,260    $

    1 - 3 Year     3 -5 Years    
376    $
22,351     
22,727    $

-    $
25,527     
25,527    $

338    $
2,668     
3,006    $

    More than  
5 Years

- 
- 
- 

In  January  2012,  we  entered  into  a  lease  agreement  for  office  and  laboratory  facilities  in  Sunnyvale,  California.  The  lease

agreement, as amended in September 2016, commenced in March 2012 and will terminate in March 2018.

On February 1, 2017, we entered into a Sublease for approximately 12,400 square feet of building space for the relocation of the
Company’s corporate headquarters to Englewood, Colorado. The lease term is 36 months and the monthly base rent for the first, second
and third years is $20.50, $21.12 and $21.75 per rentable square foot, respectively. In connection with the execution of the Sublease, the
Company paid a security deposit of approximately $22,000. The Company is also entitled to an allowance of approximately $88,000 for
certain tenant improvements relating to the engineering, design and construction of the Sublease Premises. The lease term commenced on
June 1, 2017 and will terminate in May 2020.

On May 22, 2017, the Company entered into the 2017 Loan Agreement with  affiliates  of  CRG  LP  (“ CRG”).  The  credit  facility
consists of $20,000,000 that was drawn at closing and the ability to access additional funding of up to an aggregate of $10,000,000 for a
total of $30,000,000 under the credit facility. On December 29, 2017, the Company accessed the remaining $10,000,000 available under
the CRG credit facility. The term of the loan is six years with the first four years being interest only. The outstanding principal balance
under the 2017 Loan Agreement is $30,495,000 as of December 31, 2017.

53

 
 
 
  
 
 
 
 
 
 
   
 
 
     
 
 
   
 
   
 
 
 
 
Critical Accounting Policies and Estimates

The discussion and analysis of financial condition and results of operations is based upon our consolidated financial statements,
which  have  been  prepared  in  conformity  with  accounting  principles  generally  accepted  in  the  United  States  of  America.  Certain
accounting  policies  and  estimates  are  particularly  important  to  the  understanding  of  our  financial  position  and  results  of  operations  and
require  the  application  of  significant  judgment  by  our  management  or  can  be  materially  affected  by  changes  from  period  to  period  in
economic factors or conditions that are outside of our control. As a result, they are subject to an inherent degree of uncertainty. In applying
these  policies,  management  uses  their  judgment  to  determine  the  appropriate  assumptions  to  be  used  in  the  determination  of  certain
estimates. Those estimates are based on our historical operations, our future business plans and projected financial results, the terms of
existing  contracts,  observance  of  trends  in  the  industry,  information  provided  by  our  customers  and  information  available  from  other
outside  sources,  as  appropriate.  Please  see  Note  2  to  our  consolidated  financial  statements  for  a  more  complete  description  of  our
significant accounting policies.

 Inventory

Inventory is stated at the lower of cost or net realizable value. Cost is determined on an act ual cost basis on a first-in, first-out
method. Inventory as of December 31, 2017 and 2016 is mainly finished goods but also includes a small quantity of raw materials. Lower
of  cost  or  net  realizable  value  is  evaluated  by  considering  obsolescence,  excessive  levels  of  inventory,  deterioration  and  other  factors.
Adjustments to reduce the cost of inventory to its net realizable value, if required, are made for estimated excess, obsolescence or impaired
inventory. Excess and obsolete inventory is charged to cost of revenue and a new lower-cost basis for that inventory is established and
subsequent changes in facts and circumstances do not result in the restoration or increase in that newly established cost basis.

As part of the Company’s normal business, the Company generally utilizes various finished goods inventory as sales demos to
facilitate the sale of its products to prospective customers. The Company is amortizing these demos over an estimated useful life of five
years. The amortization of the demos is charged to selling, general and administrative expense and the demos are included in the medical
equipment line within the property and equipment, net balance on the consolidated balance sheets as of December 31, 2017 and 2016.

 Impairment of Long-Lived Assets

The Company reviews long-lived assets for impairment whenever events or changes in circumstances indicate that the carrying
amount of an asset might not be recoverable. When such an event occurs, management determines whether there has been an impairment
by comparing the anticipated undiscounted future net cash flows to the related asset’s carrying value. If an asset is considered impaired,
the asset is written down to fair value, which is determined based either on discounted cash flows or appraised value, depending on the
nature of the asset. The Company has not identified any such impairment losses to date.

Revenue Recognition

The Company recognizes revenue net of sales taxes from the sale of its products, a radiofrequency generator (including a reusable
handpiece), single-use treatment tips and ancillary consumables. Revenue is recognized upon shipment, provided that persuasive evidence
of an arrangement exists, the price is fixed or determinable and collection of the resulting receivable is reasonably assured. Sales of our
products are subject to regulatory requirements that vary from country to country. The Company has regulatory clearance, or can sell its
products without a clearance, in many countries throughout the world, including countries within the following regions: North America,
Latin America, Europe, the Middle East and Asia Pacific.

 The  Company  also  sells  a  small  number  of  extended  service  agreements  on  certain  products  for  the  period  subsequent  to  the
normal  one-year  warranty  provided  with  the  original  product  sale.  Revenue  is  recognized  over  the  service  agreement  period.  Revenue
from sale of such extended service agreements was immaterial for the years ended December 31, 2017 and 2016.

54

 
 
 
  
 
 
 
 
 
 
 
 
When a sales agreement involves multiple deliverables, such as extended warranties, the multiple deliverables are evaluated to
determine the units of accounting. Judgment is required to properly identify the accounting units of multiple element transactions and the
manner  in  which  revenue  is  allocated  among  the  accounting  units.  Judgments  made,  or  changes  to  judgments  made,  may  significantly
affect the timing or amount of revenue recognition.

Revenue  related  to  the  multiple  elements  is  allocated  to  each  unit  of  accounting  using  the  relative  selling  price  hierarchy.
Consistent  with  accounting  guidance,  the  selling  price  is  based  upon  vendor  specific  objective  evidence  (“VSOE”).  If  VSOE  is  not
available, third party evidence (“TPE”) is used to establish the selling price. In the absence of VSOE or TPE, estimated selling price is
used.

The Company does not provide its customers with a right of return.

Allowance for Doubtful Accounts

We  make  ongoing  assumptions  relating  to  the  collectibility  of  our  accounts  receivable  in  our  calculation  of  the  allowance  for
doubtful  accounts. In determining the amount of the allowance, we make judgements about the creditworthiness of customers based on
ongoing credit evaluations and assess current economic trends affecting our customers that might impact the level of credit losses in the
future and result in different rates of bad debts than previously seen. We also consider our historical level of credit losses. As of December
31, 2017 and 2016, the allowance for doubtful accounts was $221,000 and $0, respectively.

Product Warranty

The Company’s products are generally subject to a one-year warranty, which provides for the repair, rework or replacement of
products (at the Company’s option) that fail to perform within stated specification. The Company has assessed the historical claims and, to
date, product warranty claims have not been significant.

Research and Development

Research  and  development  costs  are  charged  to  operations  as  incurred.  Research  and  development  costs  include,  but  are  not
limited  to,  payroll  and  personnel  expenses,  prototype  materials,  laboratory  supplies,  consulting  costs,  and  allocated  overhead,  including
rent, equipment depreciation, and utilities.

Income Taxes

Accounting for income taxes requires that deferred tax assets and liabilities be recognized using enacted tax rates for the effect of
temporary  differences  between  the  book  and  tax  bases  of  recorded  assets  and  liabilities.  The  liability  method  is  used  in  accounting  for
income taxes. Deferred tax assets and liabilities are determined based on the differences between financial reporting and the tax basis of
assets  and  liabilities,  and  are  measured  using  the  enacted  tax  rates  and  laws  that  will  be  in  effect  when  the  differences  are  expected  to
reverse. Deferred tax assets may be reduced by a valuation allowance if it is more likely than not that some or all of the deferred tax asset
will not be realized. We evaluate annually the realizability of our deferred tax assets by assessing our valuation allowance and by adjusting
the amount of such allowance, if necessary. The factors used to assess the likelihood of realization include our forecast of future taxable
income and available tax planning strategies that could be implemented to realize the net deferred tax assets. As of December 31, 2017 and
2016, the Company has recorded a full valuation allowance for our deferred tax assets based on our historical losses and the uncertainty
regarding our ability to project future taxable income. In future periods if we are able to generate income, we may reduce or eliminate the
valuation allowance.

55

 
 
 
 
 
 
 
 
 
 
 
 
   
Accounting for Uncertainty in Income Taxes

We  consider  many  factors  when  evaluating  and  estimating  our  tax  positions  and  t ax  benefits,  which  may  require  periodic
adjustments  and  which  may  not  accurately  anticipate  actual  outcomes.  The  first  step  is  to  evaluate  the  tax  position  for  recognition  by
determining  if  the  weight  of  available  evidence  indicates  that  it  is  more  likely  than  not  that  the  position  will  be  sustained  on  audit,
including resolution of related appeals or litigation processes, if any. The second step is to measure the tax benefit as the largest amount
that is more than 50% likely of being realized upon ultimate settlement. Whether the more-likely-than-not recognition threshold is met for
a tax position is a matter of judgment based on the individual facts and circumstances of that position evaluated in light of all available
evidence.

Accounting for Stock-Based Compensation

Stock-based compensation cost is measured at grant date, based on the fair value of the award, and is recognized as expense over
the employee’s service period. The Company recognizes compensation expense on a straight-line basis over the requisite service period of
the award.

We  determined  that  the  Black-Scholes  option  pricing  model  is  the  most  appropriate  method  for  determining  the  estimated  fair
value  for  stock  options  and  purchase  rights  under  the  2017  ESPP.  The  Black-Scholes  option  pricing  model  requires  the  use  of  highly
subjective and complex assumptions which determine the fair value of share-based awards, including the option’s expected term and the
price volatility of the underlying stock.

Equity instruments issued to nonemployees are recorded at their fair value on the measurement date and are subject to periodic

adjustment as the underlying equity instruments vest.

Recent Accounting Pronouncements

In May 2014, as part of its ongoing efforts to assist in the convergence of accounting principles generally accepted in the United
States of America (“U.S. GAAP”) and International Financial Reporting Standards (“IFRS”), the Financial Accounting Standards Board
(“FASB”)  issued Accounting  Standards  Update  (“ASU”)  2014-09,  “Revenue  from  Contracts  with  Customers  (Topic  606).”  The  new
guidance sets forth a new five-step revenue recognition model which replaces the prior revenue recognition guidance in its entirety and is
intended to eliminate numerous industry-specific pieces of revenue recognition guidance that have historically existed in U.S. GAAP. The
underlying principle of the new standard is that a business or other organization will recognize revenue to depict the transfer of promised
goods or services to customers in an amount that reflects what it expects in exchange for the goods or services. The standard also requires
more  detailed  disclosures  and  provides  additional  guidance  for  transactions  that  were  not  addressed  completely  in  the  prior  accounting
guidance.  The  ASU  provides  alternative  methods  of  initial  adoption  and  is  effective  for  annual  and  interim  periods  beginning  after
December 15, 2017. The FASB has issued several updates to the standard which i) defer the original effective date from January 1, 2017 to
January 1, 2018, while allowing for early adoption as of January 1, 2017 (ASU 2015-14); ii) clarify the application of the principal versus
agent guidance (ASU 2016-08); iii) clarify the guidance on inconsequential and perfunctory promises and licensing (ASU 2016-10); and
clarify the guidance on certain sections of the guidance providing technical corrections and improvements (ASU 2016-10). In May 2016,
the  FASB  issued  ASU  2016-12,  “Revenue  from  Contracts  with  Customers  (Topic  606)  Narrow-Scope  Improvements  and  Practical
Expedients”, to address certain narrow aspects of the guidance including collectibility criterion, collection of sales taxes from customers,
noncash consideration, contract modifications and completed contracts. This issuance does not change the core principle of the guidance in
the initial topic issued in May 2014.

We  did  not  early  adopt  this  guidance,  and  accordingly,  will  adopt  this  new  standard  effective  January  1,  2018.  The  guidance
permits the use of either a full retrospective or modified retrospective transition method as of the adoption date. We currently plan to adopt
the standard using the modified retrospective approach.  Should the adoption of Accounting Standards Codification (“ASC”) 606 under
the  modified  retrospective  method  result  in  the  deferral  of  revenue  previously  recognized,  or  the  recognition  of  revenue  previously
deferred under ASC 605 beyond January 1, 2018, we would record a cumulative catch-up adjustment at January 1, 2018.

56

 
 
 
  
 
 
 
 
 
 
 
As part of our  preliminary  evaluation,  we  have  also  considered  the  impact  of  the  guidance  in ASC  340-40,  “Other Assets  and
Deferred Costs; Contracts with Customers”, with respect to capitalization and amortization of incremental costs of obtaining a contract.
This  guidance,  requires  the  capitalization  of  all  incremental  costs  that  the  Company  incurs  to  obtain  a  contract  with  a  customer  that  it
would not have incurred if the contract had not been obtained, provided the Company expects to recover the costs. We do not believe that
we will be required to capitalize any additional costs of obtaining the contract or additional sales commissions.

We  have  set  up  a  team  for  the  implementation  of  the  new  revenue  recognition  accounting  standard.  Based  on  preliminary
analysis, we expect that the new standard will not significantly impact the recognition of product sales given their point of sale nature. We
are still in the process of evaluating our arrangements with distributors under ASC 606.

In  July  2015,  the  FASB  issued ASU  2015-11,  “ Simplifying  the  Measurement  of  Inventory”  (“ASU  2015-11”). ASU  2015-11
requires that an entity should measure inventory within the scope of this pronouncement at the lower of cost and net realizable value. Net
realizable value is the estimated selling prices in the ordinary course of business, less reasonably predictable costs of completion, disposal,
and transportation. The pronouncement does not apply to inventory that is being measured using the last-in, first-out (“LIFO”) method or
the  retail  inventory  method.  Subsequent  measurement  is  unchanged  for  inventory  measured  using  LIFO  or  the  retail  inventory  method.
ASU 2015-11 was effective for the Company’s fiscal year beginning January 1, 2017. The adoption did not have a significant impact on
the consolidated financial statements.

In February 2016, the FASB issued ASU 2016-02, “ Leases (Topic 842)”. Under this guidance, an entity is required to recognize
right-of-use assets and lease liabilities on its balance sheet and disclose key information about leasing arrangements. This guidance offers
specific  accounting  guidance  for  a  lessee,  a  lessor  and  sale  and  leaseback  transactions.  Lessees  and  lessors  are  required  to  disclose
qualitative  and  quantitative  information  about  leasing  arrangements  to  enable  a  user  of  the  financial  statements  to  assess  the  amount,
timing and uncertainty of cash flows arising from leases. This guidance is effective for annual reporting periods beginning after December
15,  2018,  including  interim  periods  within  the  reporting  period,  and  requires  a  modified  retrospective  adoption,  with  early  adoption
permitted. We are currently evaluating the effect of the adoption of this guidance on our consolidated financial statements.

In March 2016, the FASB issued ASU 2016-09, “ Compensation – Stock Compensation (Topic 718): Improvements to Employee
Share-Based  Payment Accounting”.  This  guidance  identifies  areas  for  simplification  involving  several  aspects  of  accounting  for  share-
based  payment  transactions,  including  the  income  tax  consequences,  classification  of  awards  as  either  equity  or  liabilities,  an  option  to
recognize  gross  stock  compensation  expense  with  actual  forfeitures  recognized  as  they  occur,  as  well  as  certain  classifications  on  the
statement  of  cash  flows.  We  adopted  this  standard  on  January  1,  2017  and  have  elected  to  continue  to  estimate  forfeitures  expected  to
occur to determine the amount of compensation cost to be recognized in each period. The adoption did not have a significant impact on the
consolidated financial statements.

In August 2016, the FASB issued ASU No. 2016-15, “Statement of Cash Flows, Classification of Certain Cash Receipts and Cash
Payments (Topic 230)”. This guidance addresses specific cash flow issues with the objective of reducing the diversity in practice for the
treatment  of  these  issues.  The  areas  identified  include:  debt  prepayment  or  debt  extinguishment  costs;  settlement  of  zero-coupon  debt
instruments;  contingent  consideration  payments  made  after  a  business  combination;  proceeds  from  the  settlement  of  insurance  claims;
proceeds from the settlement of corporate-owned life insurance policies; distributions received from equity method investees; beneficial
interests in securitization transactions and application of the predominance principle with respect to separately identifiable cash flows. This
guidance  is  effective  for  annual  reporting  periods  beginning  after  December  15,  2017,  including  interim  periods  within  that  reporting
period, with early adoption permitted. We plan to adopt this guidance as of January 1, 2018 and believe the adoption of the guidance will
not have a significant impact on the consolidated financial statements.

57

 
 
 
 
 
 
 
 
In August  2016,  the  FASB  issued ASU  No.  2016-18,  Statement  of  Cash  Flows,  Restricted  Cash  (Topic  230).  This  guidance
requires  that  a  statement  of  cash  flows  explain  the  total  change  during  the  period  of  cash,  cash  equivalents,  and  amounts  generally
described as restricted cash or restricted cash equivalents. Amounts described as restricted cash and restricted cash equivalents should be
included  with  cash  and  cash  equivalents  when  reconciling  the  beginning  of  period  and  end  of  period  to  total  amounts  shown  on  the
statement  of  cash  flows.  This  guidance  is  effective  for  annual  reporting  periods  beginning  after  December  15,  2017,  including  interim
periods within that reporting period, with early adoption permitted. We plan to adopt this guidance as of January 1, 2018 and believe the
adoption of the guidance will not have a significant impact on the consolidated financial statements.

In  May  2017,  the  FASB  issued ASU  No.  2017-09,  “ Compensation  -  Stock  Compensation  (Topic  718),  Scope  of  Modification
Accounting”. This pronouncement provides guidance about which changes to the terms or conditions of a share-based payment award may
require an entity to apply modification accounting under Topic 718.  This guidance is effective for annual reporting periods beginning after
December 15, 2017, including interim periods within that reporting period, with early adoption permitted. We plan to adopt this guidance
as of January 1, 2018 and believe the adoption of the guidance will not have a significant impact on the consolidated financial statements. 

We have reviewed other recent accounting pronouncements and concluded they are either not applicable to the business, or no

material effect is expected on the consolidated financial statements as a result of future adoption.

Off-Balance Sheet Transactions

We do not have any off-balance sheet transactions.

Trends, Events and Uncertainties

Research, development and commercialization of new technologies and products is, by its nature, unpredictable. Although we will
undertake  development  efforts,  including  efforts,  with  commercially  reasonable  diligence,  there  can  be  no  assurance  that  we  will  have
adequate capital to develop or commercialize our technology to the extent needed to create future sales to sustain our operations.

We cannot assure you that our technology will be adopted, that we will ever earn revenues sufficient to support our operations, or
that we will ever be profitable. Furthermore, since we have no committed source of financing, we cannot assure you that we will be able to
raise money as and when we need it to continue our operations. If we cannot raise funds as and when we need them, we may be required
to severely curtail, or even to cease, our operations.

Other  than  as  discussed  above  and  elsewhere  in  this Annual  Report  on  Form  10-K,  we  are  not  aware  of  any  trends,  events  or

uncertainties that are likely to have a material effect on our financial condition.

Item 7A. Quantitative and Qualitative Disclosures about Market Risk.

As a "smaller reporting company" as defined by Item 10 of Regulation S-K, the Company is not required to provide information

required by this Item.

Item 8. Financial Statements and Supplementary Data

See pages beginning with page F-1.

Item 9. Changes in and Disagreements with Accountants on Accounting and Financial Disclosure

None.

58

 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
Item 9A. Controls and Procedures

Evaluation of Disclosure Controls and Procedures

We maintain disclosure controls and procedures (as  defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act that are
designed  to  ensure  that  information  required  to  be  disclosed  in  our  reports  filed  under  the  Exchange  Act,  is  recorded,  processed,
summarized and reported within the time periods specified in the Securities and Exchange Commission’s rules and forms, and that such
information is accumulated and communicated to our management, including our principal executive officer and principal financial and
accounting officer, as appropriate, to allow timely decisions regarding required disclosure. 

We  carried  out  an  evaluation  under  the  supervision  and  with  the  participation  of  management,  including  our  Chief  Executive
Officer  and  Chief  Financial  Officer,  of  the  effectiveness  of  the  design  and  operation  of  our  disclosure  controls  and  procedures  as  of
December  31,  2017,  the  end  of  the  period  covered  by  this Annual  Report  on  Form  10-K.  Based  upon  the  evaluation  of  our  disclosure
controls and procedures as of December 31, 2017, our Chief Executive Officer and Chief Financial Officer concluded that, as of such date,
our disclosure controls and procedures were effective at the reasonable assurance level. 

Management’s Report on Internal Control over Financial Reporting

Our management is responsible for establishing and maintaining adequate internal control over financial reporting as defined in
Rules 13a-15(f) and 15d-15(f) promulgated under the Exchange Act as a process designed by, or under the supervision of, our pri ncipal
executive  officer  and  principal  financial  officer  and  effected  by  our  board  of  directors,  management,  and  other  personnel,  to  provide
reasonable  assurance  regarding  the  reliability  of  financial  reporting  and  the  preparation  of  financial  statements  for  external  purposes  in
accordance with U.S. GAAP and includes those policies and procedures that:

●

●

●

Pertain to the maintenance of records that in reasonable detail accurately and fairly reflect the transactions and dispositions
of our assets;
Provide  reasonable  assurance  that  transactions  are  recorded  as  necessary  to  permit  preparation  of  financial  statements  in
accordance  with  generally  accepted  accounting  principles,  and  that  our  receipts  and  expenditures  are  being  made  only  in
accordance with authorizations of our management and directors; and
Provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of our
assets that could have a material effect on the financial statements.

Because of  our  inherent  limitations,  our  internal  control  over  financial  reporting  may  not  prevent  or  detect  misstatements.
Therefore,  even  those  systems  determined  to  be  effective  can  provide  only  reasonable  assurance  with  respect  to  financial  statement
preparation  and  presentation.  Projections  of  any  evaluation  of  effectiveness  to  future  periods  are  subject  to  the  risk  that  controls  may
become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.

Our management assessed the effectiveness of our internal control over financial reporting as of December 31, 201 7. In making
this  assessment,  management  used  the  criteria  set  forth  by  the  Committee  of  Sponsoring  Organizations  of  the  Treadway  Commission
(COSO)  in  Internal  Control  –  Integrated  Framework  (2013  Framework).  Based  on  this  assessment,  our  management,  with  the
participation  of  our  Chief  Executive  Officer  (principal  executive  officer)  and  our  Chief  Financial  Officer  (principal  financial  and
accounting officer), has concluded that, as of December 31, 2017, our internal control over financial reporting was effective based on those
criteria.

Our independent registered public accounting firm, BPM LLP, which audited the consolidated financial statements in this Annual
Report on Form 10-K, independently assessed the effectiveness of the Company’s internal control over financial reporting.  BPM LLP has
issued an attestation report, which appears as part of this Annual Report on Form 10-K.

Changes in Internal Control over Financial Reporting

There were no changes during the last fiscal quarter that have materially affected, or are reasonably likely to materially affect, our

internal control over financial reporting.

59

 
 
 
 
 
 
 
 
 
 
 
 
 
 
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Stockholders and Board of Directors of

Viveve Medical, Inc.

Opinion on Internal Control over Financial Reporting

We have audited the internal control over financial reporting of Viveve Medical, Inc. (a Delaware corporation) and its subsidiaries (the
“Company”)  as  of  December  31,  2017,  based  on  criteria  established  in Internal  Control—Integrated  Framework  (2013)  issued  by  the
Committee of Sponsoring Organizations of the Treadway Commission (the “COSO criteria”). In our opinion, the Company maintained, in
all material respects, effective internal control over financial reporting as of December 31, 2017, based on the COSO criteria.

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) (“ PCAOB”),
the  consolidated  balance  sheets  as  of  December  31,  2017  and  2016  and  the  related  consolidated  statements  of  operations  and
comprehensive loss, stockholders’ equity (deficit), and cash flows for each of the two years in the period ended December 31, 2017, and
the  related  notes  (collectively  referred  to  as  the  “consolidated  financial  statements”)  of  the  Company,  and  our  report  dated  March  15,
2018, expressed an unqualified opinion on those consolidated financial statements.

Basis for Opinion

The Company’s management is responsible for maintaining effective internal control over financial reporting, and for its assessment of the
effectiveness of internal control over financial reporting, included in the accompanying Management’s Report on Assessment of Internal
Controls over Financial Reporting. Our responsibility is to express an opinion on the Company’s internal control over financial reporting
based on our audit. We are a public accounting firm registered with the PCAOB and are required to be independent with respect to the
Company  in  accordance  with  the  U.S.  federal  securities  laws  and  the  applicable  rules  and  regulations  of  the  Securities  and  Exchange
Commission and the PCAOB.

We conducted our audit in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to
obtain reasonable assurance about whether effective internal control over financial reporting was maintained in all material respects. Our
audit of internal control over financial reporting included obtaining an understanding of internal control over financial reporting, assessing
the risk that a material weakness exists, and testing and evaluating the design and operating effectiveness of internal control based on the
assessed risk. Our audit also included performing such other procedures as we considered necessary in the circumstances. We believe that
our audit provides a reasonable basis for our opinion.

Definition and Limitations of Internal Control over Financial Reporting

A company ’s  internal  control  over  financial  reporting  is  a  process  designed  to  provide  reasonable  assurance  regarding  the  reliability  of
financial  reporting  and  the  preparation  of  financial  statements  for  external  purposes  in  accordance  with  generally  accepted  accounting
principles. A company’s internal control over financial reporting includes those policies and procedures that (1) pertain to the maintenance
of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the assets of the company; (2) provide
reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with generally
accepted accounting principles, and that receipts and expenditures of the company are being made only in accordance with authorizations
of  management  and  directors  of  the  company;  and  (3)  provide  reasonable  assurance  regarding  prevention  or  timely  detection  of
unauthorized acquisition, use, or disposition of the company’s assets that could have a material effect on the financial statements.

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, projections of
any  evaluation  of  effectiveness  to  future  periods  are  subject  to  the  risk  that  controls  may  become  inadequate  because  of  changes  in
conditions, or that the degree of compliance with the policies or procedures may deteriorate.

/s/ BPM LLP

San Jose, California
March 15, 2018

60

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Item 9B. Other Information

None.

Item 10. Directors, Executive Officers and Corporate Governance

PART III

The  information  required  by  this  Item  10  will  be  included  in  our  definitive  proxy  statement  to  be  filed  with  the  SEC  with

respect to our 2018 Annual Meeting of Stockholders and is incorporated herein by reference.

 Item 11. Executive Compensation

The information required by this Item 11 will be included in our definitive proxy statement to be filed with the SEC with

respect to our 2018 Annual Meeting of Stockholders and is incorporated herein by reference.

Item 12. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters

The information required by this Item 12 will be included in our definitive proxy statement to be filed with the SEC with respect

to our 2018 Annual Meeting of Stockholders and is incorporated herein by reference.

Item 13. Certain Relationships and Related Transactions, and Director Independence 

The information required by this Item 13 will be included in our definitive proxy statement to be filed with the SEC with respect

to our 2018 Annual Meeting of Stockholders and is incorporated herein by reference.

Item 14. Principal Accounting Fees and Services

The information required by this Item 14 will be included in our definitive proxy statement to be filed with the SEC with respect

to our 2018 Annual Meeting of Stockholders and is incorporated herein by reference.

61

 
 
 
  
 
 
 
 
 
 
 
 
  
 
 
PART IV

Item 15. Exhibits, Financial Statement Schedules

Financial Statements

See Index to Consolidated Financial Statements at Item 8 herein.

Financial Statement Schedules have been omitted as they are either not required, not applicable, or the information is otherwise

included.

Exhibit Index

Exhibit
No.

Description

2.1

Agreement  and  Plan  of  Merger  dated  May  9,  2014  by  and  among  Viveve,  Inc.,  PLC Systems,  Inc.  and  PLC  Systems
Acquisition Corporation (1)

2.1.1 Amendment to Agreement and Plan of Merger (1)
RenalGuard Reorganization Agreement (2)
2.2
Certificate of Conversion for Delaware(3)
3.1
Amended and Restated Certificate of Incorporation(4)
3.2
Articles of Amendment to the Articles of Continuance of Viveve Medical, Inc. (5)
3.3
Amended and Restated Bylaws(4)
3.4
Common Stock Purchase Warrant issued on February 17, 2015 to Scott Durbin (6)+
4.1
Common Stock Purchase Warrant issued on February 17, 2015 to Jim Robbins (6)+
4.2
Common Stock Purchase Warrant issued on February 17, 2015 to Patricia Scheller (6)+
4.3
Common Stock Purchase Warrant issued on May 12, 2015 to James Atkinson (6)+
4.4
Common Stock Purchase Warrant issued on December 16, 2015 to James Atkinson (6)+
4.5
4.6
Common Stock Purchase Warrant issued on December 16, 2015 to Jim Robbins (6)+
4.7 Warrant to Purchase Common Stock issued on April 1, 2016 to Dynamic Medical Technologies (Hong Kong) Limited (3)
4.8 Warrant to Purchase Common Stock issued on May 11, 2016 to Theresa Stern (7)
4.9 Warrant to Purchase Common Stock issued on May 11, 2016 to Chris Rowan (7)
4.10 Warrant to Purchase Common Stock issued on June 20, 2016 to Western Alliance Bank (8)
4.11 Warrant to Purchase Shares of Common Stock of Viveve Medical, Inc., dated May 25, 2017, by and between Viveve Medical,

Inc. and CRG Partners III - Parallel Fund "A" L.P. (9)

4.12 Warrant to Purchase Shares of Common Stock of Viveve Medical, Inc., dated May 25, 2017, by and between Viveve Medical,

4.13
10.1
10.2

10.3

Inc. and CRG Partners III L.P. (9)
Specimen Common Stock Certificate (10)
Form of Securities Purchase Agreement dated May 9, 2014 (11)
Securities Purchase Agreement, dated May 9, 2014, by and among the Registrant and GBS Venture Partners as trustee for GBS
BioVentures III Trust (11)
Escrow Deposit Agreement, dated May 9, 2014 by and among the Registrant, Palladium Capital Advisors LLC, Middlebury
Securities and Signature Bank, as escrow agent (11)
Registration Rights Agreement, dated May 9, 2014 (11)
First Amendment to Registration Rights Agreement, dated February 19, 2015 (12)
Right to Shares Letter Agreement dated May 9, 2014 between the Registrant and GCP IV LLC (11)

10.4
10.5
10.6
 10.7 Amendment dated September 10, 2014 to Securities Purchase Agreement dated February 22, 2013 (13)
10.8 Amendment dated September 11, 2014 to Securities Purchase Agreement dated February 22, 2013 (13)
10.9
10.10 Employment Agreement by and between the Registrant and Patricia K. Scheller, dated February 27, 2018 (15)+
10.11 Employment Agreement by and between the Registrant and Scott C. Durbin, dated March 1, 2018 (15)+
10.12 Loan and Security Agreement dated September 30, 2014 between Viveve, Inc. and Square 1 Bank (16)

PLC Systems Inc. 2013 Stock Option and Incentive Plan, as amended (14) +

62

 
 
 
 
 
 
 
 
 
 
 
First Amendment to Loan and Security Agreement dated February 19, 2015 between Viveve, Inc. and Square 1 Bank (12)
Intellectual Property Security Agreement dated September 30, 2014 between Viveve, Inc. and Square 1 Bank (16)

10.13
10.14
10.15 Unconditional Guaranty issued by the Registrant in favor of Square 1 Bank (16)
10.16

Intellectual Property Assignment and License Agreement dated February 10, 2006, as amended, between Dr. Edward Knowlton
and TivaMed, Inc (14)

10.17 Development and Manufacturing Agreement dated June 12, 2006 between TivaMed, Inc. and Stellartech Research Corporation

(14)

10.18 Amended  and  Restated  Development  and  Manufacturing Agreement  dated  October  4,  2007  between  TivaMed,  Inc.  and

Stellartech Research Corporation (14)

10.19 Right to Shares Letter Agreement, dated as of September 23, 2014 by and between the Registrant and GCP IV LLC (14)
10.20 Right to Shares Letter Agreement, dated as of September 23, 2014 by and between the Registrant and G-Ten Partners LLC (14)
10.21 Convertible Note Termination Agreement, dated May 9, 2014 by and between Viveve, Inc. and 5AM Ventures II, LP (17)
10.22 Convertible Note Termination Agreement, dated May 9, 2014 by and between Viveve, Inc. and 5AM Co-Investors II, LP (17)
10.23 Convertible Note Exchange Agreement, dated May 9, 2014 by and between Viveve, Inc. and GBS Venture Partners Limited,

trustee for GBS BioVentures III (17)

10.24 Warrant Termination Agreement, dated as of May 9, 2014, by and between Viveve, Inc. and 5AM Ventures II, LP (17)
10.25 Warrant Termination Agreement, dated as of May 9, 2014, by and between Viveve, Inc. and 5AM Co-Investors II, LP (17)
10.26 Warrant Termination Agreement, dated as of May 9, 2014, by and between Viveve, Inc. and GBS Venture Partners Limited,

trustee for GBS BioVentures III (17)

10.27 Employment Agreement by and between the Registrant and James G. Atkinson, dated February 27, 2018 (15)+
First Amendment to Lease dated January 15, 2015 between The Castine Group and Viveve, Inc. (18)
10.28
Second Amendment to Loan and Security Agreement dated May 14, 2015 between Viveve, Inc. and Square 1 Bank (18)
10.29
Form of Securities Purchase Agreement dated May 12, 2015 (18)
10.30
10.31
Form of Registration Rights Agreement dated May 12, 2015 (18)
10.32 Letter Agreement with Stonepine Capital dated May 12, 2015 (18)
10.33
10.34
10.35 Third Amendment to Loan and Security Agreement dated November 30, 2015 between Pacific Western Bank, as successor in

Form of Securities Purchase Agreement dated November 20, 2015 (19)
Form of Registration Rights Agreement dated November 20, 2015 (19)

10.36

interest by merger to Square 1 Bank, and Viveve, Inc. (20)
Fourth Amendment to Loan and Security Agreement dated March 18, 2016 between Pacific Western Bank, as successor in
interest by merger to Square 1 Bank, and Viveve, Inc. (6)

10.37 Viveve Medical, Inc. Amended and Restated Independent Director Compensation Policy (20)
10.38 Viveve Medical, Inc. Amended and Restated 2013 Stock Option and Incentive Plan (21)
10.39

Second Amendment to Standard Industrial/Commercial Multi-Tenant Lease- Gross, dated September 12, 2016 between Viveve,
Inc. and Commercial Street Properties, LLC. (22)

10.40 Loan and Security Agreement dated as of June 20, 2016 by and among Viveve Medical, Inc., Viveve, Inc. and Western

10.41

10.42

Alliance Bank (8)
Intellectual Property Security Agreement dated as of June 20, 2016 between Viveve Medical, Inc. and Western Alliance
Bank (8)
Sublease Agreement, entered into on February 1, 2017 and effective as of January 26, 2017, between Viveve Medical, Inc. and
Ingredion Incorporated (23)

10.43 Waiver and First Amendment to Loan and Security Agreement, dated January 13, 2017, between Viveve Medical, Inc., Viveve,

Inc. and Western Alliance Bank (24)
Security Agreement, dated May 25, 2017, by and between Viveve Medical, Inc., Viveve, Inc. and CRG Servicing LLC (9)

10.44

63

 
 
 
10.45

Patent and Trademark Security Agreement, dated May 25, 2017, by and between Viveve Medical, Inc., Viveve, Inc. and CRG
Servicing LLC (9)

10.46 Term Loan Agreement, dated May 22, 2017, among Viveve Medical, Inc., Viveve, Inc., CRG Servicing LLC, as administrative

agent, and certain lenders (25)

10.47 Exclusive Distributorship Agreement, dated August 8. 2017, by and between Viveve Medical, Inc. and InControl Medical, LLC

(26)

10.48 Membership Subscription Agreement, dated August 1, 2017, by and between Viveve Medical, Inc. and InControl Medical,

LLC (26)

10.49 Waiver No. 2 to Loan Agreement, dated December 12, 2017, among Viveve Medical, Inc., CRG Servicing LLC and the

lenders party thereto (27)

10.50 Amendment to the Amended and Restated 2013 Stock Option and Incentive Plan (28)
10.51
10.52
14.1
21
23.1
24.1
31.1

2017 Employee Stock Purchase Plan (28)
Forms of Indemnification Agreement*
Code of Conduct, adopted September 23, 2014 (29)
List of the Registrant’s Subsidiaries (30)
Consent of BPM LLP*
Power of Attorney* (included on signature page hereto)
Certification of the Company ’s Principal Executive Officer pursuant to 15d-15(e), under the Securities and Exchange Act of
1934*
Certification of the Company ’s Principal Financial Officer pursuant to 15d-15(e), under the Securities and Exchange Act of
1934*
Certification of the Company ’s Chief Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section
906 of the Sarbanes-Oxley Act of 2002**

31.2

32.1

 32.2 Certification of the Company’s Chief Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906

of the Sarbanes-Oxley Act of 2002**

101.INS XBRL Instance Document*
101.SCH XBRL Taxonomy Extension Schema Document*
101.CAL XBRL Taxonomy Extension Calculation Linkbase Document*
101.DEF XBRL Taxonomy Extension Definition Linkbase Document*
101.LAB XBRL Taxonomy Extension Label Linkbase Document*
101.PRE XBRL Taxonomy Extension Presentation Linkbase Document*

Filed herewith.
These exhibits are furnished, not filed.

*
**
+ Management contract or compensation plan, contract or arrangement.
(1)

Incorporated by reference to Annex A to the Registrant ’s Definitive Proxy Statement on Schedule 14A filed with the Securities and
Exchange Commission on August 11, 2014.
Incorporated by reference to Annex B to the Registrant’s Definitive Proxy Statement on Schedule 14A filed with the Securities and
Exchange Commission on August 11, 2014.
Incorporated by reference from the Form 10-Q filed with the Securities and Exchange Commission on May 13, 2016.
Incorporated by reference from the Form 8-K filed with the Securities and Exchange Commission on August 17, 2017.
Incorporated by reference from the Form 8-K filed with the Securities and Exchange Commission on April 14, 2016.
Incorporated by reference from the Form 10-K filed with the Securities and Exchange Commission on March 24, 2016.
Incorporated by reference to the Registrant’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on

(2)

(3)
(4)
(5)
(6)
(7)

August 11, 2016.

(8)

Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on June

21, 2016.

(9)

Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on June

1, 2017.

64

 
 
 
 
 
(10) Incorporated by reference to the Registrant’s Registration Statement on Form S-8 filed with the Securities and Exchange Commission

on October 5, 2017.

(11) Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on May

14, 2014.

(12) Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on

February 25, 2015.

(13) Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on

September 16, 2014.

(14) Incorporated by reference to the Registrant’s on Form S-1 filed with the Securities and Exchange Commission on November 21, 2014.
(15) Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on

March 1, 2018.

(16) Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on

October 3, 2014.

(17) Incorporated by reference to the Amendment No. 1 Registrant’s Form S-1 filed with the Securities and Exchange Commission on

January 26, 2015.

(18) Incorporated by reference to the Registrant’s  Quarterly  Report  on  Form  10-Q  for  the  quarter  ended  March  31,  2015  filed  with  the

Securities and Exchange Commission on May 15, 2015.

(19) Incorporated by reference to the registrants Current Report on Form 8-K filed with the Securities and Exchange Comm ission on

November 25, 2015.

(20) Incorporated by reference to the registrants Current Report on Form 8-K filed with the Securities and Exchange Commission on May

16, 2017.

(21) Incorporated by reference to Appendix A to the Registrant’s Proxy Statement on Schedule 14A filed with the Securities and Exchange

Commission on July 7, 2017.

(22) Incorporated by reference to the Registrant’s Quarterly Report on Form 10-Q, filed with the SEC on November 10, 2016.
(23) Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the SEC on February 3, 2017.
(24) Incorporated by reference from the Form 8-K filed with the Securities and Exchange Commission on January 13, 2017.
(25) Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on May

24, 2017.

(26) Incorporated by reference to the Registrant’s Quarterly Report on Form 10-Q, filed with the SEC on November 8, 2017.
(27) Incorporated by reference to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on

December 14, 2017.

(28) Incorporated by reference to the Registrant’s Proxy Statement on Schedule 14A filed with the Securities and Exchange Commission on

July 7, 2017.

(29) Incorporated by reference to the Registrant’s Annual Report on Form 10-K filed with the Securities and Exchange Commission on

March 16, 2015.

(30) Incorporated by reference  to the Registrant's Annual Report on Form 10-K filed with the Securities and Exchange Commission on

February 16, 2017.

65

 
 
 
In accordance with Section 13 or 15(d) of the Exchange Act, the Registrant caused this report to be signed on its behalf by the

undersigned, thereto duly authorized.

SIGNATURES

March 15, 2018

VIVEVE MEDICAL, INC.
(Registrant)

By: /s/ Patricia Scheller
Patricia Scheller
Chief Executive Officer

POWER OF ATTORNEY 

We, the undersigned officers and directors of Viveve Medical, Inc., hereby severally constitute and appoint  Patricia  Scheller  and
Scott Durbin, and each of them singly (with full power to each of them to act alone), our true and lawful attorneys-in-fact and agents, with
full  power  of  substitution  and  resubstitution  in  each  of  them  for  him  or  her  and,  place  and  stead,  and  in  any  and  all  capacities,  to  sign
conformed for us and in our names in the capacities indicated below any and all signatures and amendments to this report, and to file the
same, with all exhibits thereto filing date and other documents in connection therewith, with the Securities and Exchange Commission,
granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing
requisite or necessary to be done in and about the premises, as full to all intents and purposes as he or she might or could do in person,
hereby  ratifying  and  confirming  all  that  said  attorneys-in-fact  and  agents  or  any  of  them,  or  their  or  his  substitute  or  substitutes,  may
lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed by the following persons on behalf

of the Registrant in the capacities and on the dates indicated.

Signature

Title

Date

  /s/Patricia Scheller
  Patricia Scheller

  Chief Executive Officer and Director
  (Principal Executive Officer) 

  Chief Financial Officer
  (Principal Financial and Accounting Officer) 

  March 15, 2018

  March 15, 2018

  /s/Scott Durbin
  Scott Durbin

  /s/Daniel Janney
  Daniel Janney

  /s/Debora Jorn
  Debora Jorn

  /s/Lori Bush
  Lori Bush

  /s/Arlene Morris
  Arlene Morris

  /s/Jon Plexico
  Jon Plexico

  Chairman of the Board of Directors

  March 15, 2018

  Director

  Director

  Director

  Director

66

  March 15, 2018

  March 15, 2018

  March 15, 2018

  March 15, 2018

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
  
  
 
 
 
 
 
 
 
 
    
    
    
   
   
   
   
   
   
   
    
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
 
VIVEVE MEDICAL, INC.
INDEX TO CONSOLIDATED FINANCIAL STATEMENTS

Report of Independent Registered Public Accounting Firm

Consolidated Balance Sheets - December 31, 2017 and 2016

Consolidated Statements of Operations and Comprehensive Loss - Years Ended December 31, 2017 and 2016

Consolidated Statements of Stockholders’ Deficit - Years Ended December 31, 2017 and 2016

Consolidated Statements of Cash Flows - Years Ended December 31, 2017 and 2016

Page

F-2

F-3

F-4

F-5

F-6

Notes to Consolidated Financial Statements

F-7 – F-27

F-1

 
 
 
  
  
  
 
 
 
 
  
  
  
  
 
 
  
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Stockholders and Board of Directors of

Viveve Medical, Inc.

Opinion on the Financial Statements

We have audited the accompanying consolidated balance sheets of Viveve Medical, Inc. (a Delaware corporation) and its subsidiaries (the
“Company”)  as  of  December  31,  2017  and  2016,  and  the  related  consolidated  statements  of  operations  and  comprehensive  loss,
stockholders’ deficit, and cash flows for each of the two years in the period ended December 31, 2017, and the related notes (collectively
referred to as the “consolidated financial statements”). In our opinion, the consolidated financial statements present fairly, in all material
respects, the financial position of the Company as of December 31, 2017 and 2016, and the results of its operations and its cash flows for
each of the two years in the period ended December 31, 2017, in conformity with accounting principles generally accepted in the United
States of America.

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) (“ PCAOB”),
the  Company’s  internal  control  over  financial  reporting  as  of  December  31,  2017,  based  on  criteria  established  in  Internal  Control—
Integrated  Framework  (2013)  issued  by  the  Committee  of  Sponsoring  Organizations  of  the  Treadway  Commission  (COSO),  and  our
report dated March 15, 2018, expressed an unqualified opinion.

Basis for Opinion

These consolidated financial statements are the responsibility of the Company ’s management. Our responsibility is to express an opinion
on the Company’s consolidated financial statements based on our audits. We are a public accounting firm registered with the PCAOB and
are required to be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable rules and
regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audi ts in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to
obtain reasonable assurance about whether the consolidated financial statements are free of material misstatement, whether due to error or
fraud.  Our  audits  included  performing  procedures  to  assess  the  risks  of  material  misstatement  of  the  consolidated  financial  statements,
whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis,
evidence  regarding  the  amounts  and  disclosures  in  the  consolidated  financial  statements.  Our  audits  also  included  evaluating  the
accounting  principles  used  and  significant  estimates  made  by  management,  as  well  as  evaluating  the  overall  presentation  of  the
consolidated financial statements. We believe that our audits provide a reasonable basis for our opinion.

/s/ BPM LLP

We have served as the Company ’s auditor since 2013.

San Jose, California
March 15, 2018

F-2

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
VIVEVE MEDICAL, INC.
CONSOLIDATED BALANCE SHEETS
(in thousands, except share and per share data)

  December 31,

    December 31,

2017

2016

Current assets:

ASSETS

Cash and cash equivalents
Accounts receivable, net of allowance for doubtful accounts of $221 and $0 as of December

  $

  $

  $

31, 2017 and 2016, respectively

Inventory
Prepaid expenses and other current assets

Total current assets

Property and equipment, net
Investment in limited liability company
Other assets

Total assets

LIABILITIES AND STOCKHOLDERS' DEFICIT

Current liabilities:

Accounts payable
Accrued liabilities
Note payable, current portion

Total current liabilities
Note payable, noncurrent portion
Other noncurrent liabilities
Total liabilities

Commitments and contingences (Note 8)
Stockholders’ deficit:

Preferred stock, $0.0001 par value;

10,000,000 shares authorized as of December 31, 2017 and 2016; no shares issued

Common stock, $0.0001 par value;

75,000,000 shares authorized as of December 31, 2017 and 2016;
19,503,558 and 10,661,201 shares issued and outstanding as of December 31, 2017 and
2016, respectively

Additional paid-in capital

Accumulated deficit

Total stockholders’ deficit
Total liabilities and stockholders’ deficit

20,730    $

6,213     
2,390     
2,741     
32,074     
1,303     
2,500     
202     
36,079    $

4,799    $
4,605     
-     
9,404     
28,948     
327     
38,679     

-     

2     

102,979     
(105,581)    
(2,600)    
36,079    $

  $

The accompanying notes are an integral part of these consolidated financial statements.  

F-3

8,086 

2,091 
2,687 
1,066 
13,930 
483 
- 
136 
14,549 

3,086 
2,186 
1,867 
7,139 
7,762 
53 
14,954 

- 

1 

68,216 
(68,622)
(405)
14,549 

 
 
 
 
 
 
 
 
   
 
     
       
 
     
       
 
   
   
   
   
   
   
   
     
       
 
     
       
 
   
   
   
   
   
   
     
       
 
     
       
 
   
      
  
   
   
      
  
   
      
  
   
   
   
   
 
 
VIVEVE MEDICAL, INC.
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
(in thousands, except share and per share data)

Revenue
Cost of revenue

Gross profit

Operating expenses:
Research and development
Selling, general and administrative

Total operating expenses
Loss from operations

Interest expense, net
Other expense, net

Comprehensive and net loss

Net loss per share:

Basic and diluted

Weighted average shares used in computing net loss per common share

Basic and diluted

Year Ended
December 31,

2017

2016

15,288    $
7,844     
7,444     

12,343     
28,831     
41,174     
(33,730)    
(3,169)    
(60)    
(36,959)   $

7,141 
4,612 
2,529 

8,365 
12,868 
21,233 
(18,704)
(1,370)
(37)
(20,111)

(2.11)   $

(2.18)

17,496,942     

9,222,348 

  $

  $

  $

The accompanying notes are an integral part of these consolidated financial statements.

F-4

 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
     
       
 
   
   
 
     
       
 
     
       
 
   
   
   
   
   
   
 
     
       
 
     
       
 
 
     
       
 
     
       
 
   
 
 
VIVEVE MEDICAL, INC.
CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ DEFICIT
For each of the two years in the period ended December 31, 2017
(in thousands, except share data) 

Common Stock,
$0.0001 par value

Common Stock and
Paid-in

    Additional    
    Paid-In     Capital: no par value     Accumulated     Stockholders’ 

Total

Balances as of January 1, 2016    
Reverse stock split - rounding

Shares

    Amount
-    $

    Capital
-    $

    Shares
-      7,490,288    $

    Amount    

52,447    $

(48,511)   $

3,936 

Deficit

Equity
(Deficit)

adjustment

Stock-based compensation

expense

Issuance of restricted stock
awards to employees for
performance bonuses
Issuance of restricted stock
awards to directors and
consultants

Issuance of warrants
Exercise of warrants
Exercise of stock options
Reclassification upon change in

corporate domicile

June 2016 Offering, net of

issuance costs

Issuance of warrant in

-     

-     

-     

18,792     
-     
35,490     
-     

-     

-     

-     

-     
-     
-     
-     

-     

2,361     

-     

707     

-     

188     

-     

-     

246     

125     
20     
65     
-     

-     
-     
6,250     
3,020     

-     
142     
27     
14     

    7,501,919     

1     

53,063      (7,501,919)    

(53,064)    

    3,105,000     

-     

13,886     

connection with note payable    

Net loss
Balances as of December 31,

-     
-     

-     
-     

350     
-     

2016

    10,661,201     

1     

68,216     

    8,625,000     

1     

31,439     

March 2017 Offering, net of

issuance costs

Stock-based compensation

expense

Issuance of warrant in

connection with note payable    

Issuance of restricted common

shares

Issuance of restricted stock

awards to directors, employees
and consultants

November 2017 ATM Facility,

net of issuance cost

Issuance of common shares from

employee stock purchase plan    

Exercise of stock options
Exercise of warrants
Cashless exercise of warrant
Net loss
Balances as of December 31,

2017

-     

-     

35,000     

77,783     

59,249     

17,894     
7,730     
4,701     
15,000     
-     

-     

1,646     

-     

-     

-     

-     

-     
-     
-     
-     
-     

940     

260     

226     

125     

76     
31     
20     
-     
-     

-     

-     
-     

-     

-     

-     

-     

-     

-     

-     

-     
-     
-     
-     
-     

-     

-     
-     

-     

-     

-     

-     

-     

-     

-     

-     
-     
-     
-     
-     

-     

-     

-     

-     
-     
-     
-     

-     

-     

-     
(20,111)    

- 

895 

246 

125 
162 
92 
14 

- 

13,886 

350 
(20,111)

(68,622)    

(405)

-     

-     

-     

-     

-     

-     

31,440 

1,646 

940 

260 

226 

125 

-     
-     
-     
-     
(36,959)    

76 
31 
20 
- 
(36,959)

    19,503,558    $

2    $ 102,979     

-    $

-    $

(105,581)   $

(2,600)

The accompanying notes are an integral part of these consolidated financial statements.

F-5

 
 
 
 
 
 
     
 
   
 
 
 
 
 
   
 
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
 
 
VIVEVE MEDICAL, INC.
CONSOLIDATED STATEMENTS OF CASH FLOWS
(in thousands) 

Cash flows from operating activities:

Net loss
Adjustments to reconcile net loss to net cash used in operating activities:

Provision for doubtful accounts
Depreciation and amortization
Stock-based compensation
Fair value of restricted common shares issued in lieu of cash
Fair value of warrants issued
Non-cash interest expense
Changes in assets and liabilities:

Accounts receivable
Inventory
Prepaid expenses and other current assets
Other noncurrent assets
Accounts payable
Accrued and other liabilities
Other noncurrent liabilities

Net cash used in operating activities

Cash flows from investing activities:

Investment in limited liability company
Purchase of property and equipment

Net cash used in investing activities

Cash flows from financing activities:

Proceeds from sale of common stock, net of issuance costs
Proceeds from note payable
Repayments of note payable
Proceeds from issuance of common shares from employee stock purchase plan
Proceeds from exercise of stock options
Proceeds from exercise of warrant

Net cash provided by financing activities
Net increase in cash and cash equivalents

Cash and cash equivalents - beginning of period
Cash and cash equivalents - end of period

Supplemental disclosure:
Cash paid for interest
Cash paid for income taxes

Supplemental disclosure of cash flow information as of end of period:

Issuance of warrants in connection with note payable
Issuance of note payable in settlement of accrued interest
Net transfer of equipment between inventory and property and equipment
Restricted stock awards granted to employees for 2015 accrued bonuses

Year Ended
December 31,

2017

2016

  $

(36,959)   $

(20,111)

(221)    
449     
1,872     
260     
-     
1,049     

(3,901)    
(67)    
(1,675)    
(66)    
1,713     
2,419     
274     
(34,853)    

(2,500)    
(905)    
(3,405)    

31,565     
29,210     
(10,000)    
76     
31     
20     
50,902     
12,644     

8,086     
20,730    $

2,066    $
-    $

940    $
495    $
364    $
-    $

- 
111 
1,020 
- 
162 
456 

(1,498)
(1,237)
162 
2 
1,654 
1,192 
- 
(18,087)

- 
(256)
(256)

13,886 
9,910 
(4,833)
- 
14 
92 
19,069 
726 

7,360 
8,086 

803 
1 

350 
- 
99 
246 

  $

  $
  $

  $
  $
  $
  $

The accompanying notes are an integral part of these consolidated financial statements.

F-6

 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
     
       
 
     
       
 
     
       
 
   
   
   
   
   
   
     
       
 
   
   
   
   
   
   
   
   
 
     
       
 
     
       
 
   
   
   
 
     
       
 
     
       
 
   
   
   
   
   
   
   
   
 
     
       
 
   
 
     
       
 
     
       
 
 
     
       
 
 
     
       
 
     
       
 
 
  
VIVEVE MEDICAL, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

1. The Company and Basis of Presentation

Viveve Medical, Inc. (“Viveve Medical”, the “Company”, “we”, “our”, or “us”) competes in the women’s health industry in some
countries by marketing Geneveve™ as a way to improve the overall sexual well-being and quality of life of women suffering from
vaginal laxity.

Public Offering

The  Company  established  an  “at-the-market”  equity  offering  program  through  the  filing  of  a  prospectus  supplement  to  its  shelf
registration  statement  on  Form  S-3,  which  was  filed  on November  8,  2017, under  which  the  Company may offer  and  sell,  from
time-to-time, up to $25,000,000 aggregate offering price of shares of its common stock (the “November 2017 ATM Facility”). As of
December  31,  2017, the  Company  has  sold 59,249  shares  of  common  stock  under  the November  2017 ATM  Facility  for  net
proceeds of approximately $125,000.

On March  22,  2017, in  connection  with  the  closing  of  a  public  offering  (the  “  March  2017 Offering”),  the  Company  issued  an
aggregate  of 8,625,000  shares  of  common  stock,  including  the  shares  issued  in  connection  with  the  exercise  of  the  underwriters’
overallotment  option,  at  a  public  offering  price  of $4.00  per  share  for  gross  proceeds  of  approximately $34,500,000.  The  net
proceeds  to  the  Company,  after  the  deduction  of  underwriting  discounts,  commissions  and  other  offering  expenses,  were
approximately $31,440,000. 

On June 17, 2016, in connection with the closing of a public offering (the “ June 2016 Offering”), the Company issued an aggregate
of 3,105,000 shares of common stock, including the shares issued in connection with the exercise of the underwriters’ overallotment
option,  at  a  public  offering  price  of $5.00  per  share  for  gross  proceeds  of  approximately $15,525,000.  The  net  proceeds  to  the
Company,  after  the  deduction  of  underwriting  discounts,  commissions  and  other  offering  expenses,  were  approximately
$13,886,000.

Change of Corporate Domicile

O n May  9,  2016, the  Company  filed  the  necessary  Application  for  Authorization  to  Continue  into  Another  Jurisdiction  and
Statutory  Declaration  with  the  Yukon  registrar.  On  May  10, 2016,  the  Company  filed  a  Certificate  of  Incorporation  with  the
Secretary  of  State  of  the  State  of  Delaware  to  move  its  domicile  from  the  Yukon  Territory  to  Delaware.  In  connection  with  the
incorporation in Delaware, the Company's stock now has a par value of $0.0001 per share.

2. Summary of Significant Accounting Policies

Basis of Presentation

The consolidated financial statements include the accounts of the Company and our wholly-owned subsidiaries, Viveve, Inc.  and
Viveve BV. All significant intercompany accounts and transactions have been eliminated in consolidation.

Use of Estimates

The  preparation  of  consolidated  financial  statements  in  conformity  with  accounting  principles  generally  accepted  in  the  United
States  of  America  (“U .S.  GAAP”)  requires  us  to  make  estimates  and  judgments  that  affect  the  reported  amounts  of  assets,
liabilities, revenues, and expenses and the related disclosure of contingent assets and liabilities. We base our estimates on historical
experience and on various other assumptions that we believe to be reasonable under the circumstances, the results of which form the
basis  for  making  judgments  about  the  carrying  values  of  assets  and  liabilities  that  are not  readily  apparent  from  other  sources.
Actual results may differ from these estimates. In addition, any change in these estimates or their related assumptions could have an
adverse effect on our operating results.

F-7

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
Cash and Cash Equivalents

The Company considers all highly liquid investments purchased with an original maturity of three  months  or  less,  at  the  time  of
purchase,  to  be  cash  equivalents.  The  Company’s  cash  and  cash  equivalents  are  deposited  in  demand  accounts  primarily  at  one
financial institution. Deposits in this institution may, from time to time, exceed the federally insured amounts.

Concentration of Credit Risk and Other Risks and Uncertainties

To achieve profitable operations, the Company must successfully develop, manufacture, and market its products. There can be  no
assurance  that  any  such  products  can  be  developed  or  manufactured  at  an  acceptable  cost  and  with  appropriate  performance
characteristics,  or  that  such  products  will  be  successfully  marketed.  These  factors  could  have  a  material  adverse  effect  upon  the
Company’s financial results, financial position, and future cash flows.

The Company’s products likely require clearance or approvals from the U.S. Food and Drug Administration or other international
regulatory agencies prior to commencing commercial sales. There can be no assurance that the Company’s products will receive any
of these required clearances or approvals or for the indications requested. If the Company was denied such clearances or approvals
or  if  such  clearances  or  approvals  were  delayed,  it  would  have  a  material  adverse  effect  on  the  Company’s  financial  results,
financial position and future cash flows.

The  Company  is subject  to  risks  common  to  companies  in  the  medical  device  industry  including,  but not  limited  to,  new
technological  innovations,  dependence  on  key  personnel,  protection  of  proprietary  technology,  compliance  with  government
regulations,  uncertainty  of  market  acceptance  of  products,  product  liability,  and  the  need  to  obtain  additional  financing.  The
Company’s  ultimate  success  is  dependent  upon  its  ability  to  raise  additional  capital  and  to  successfully  develop  and  market  its
products.

The  Company  designs, develops,  manufactures  and  markets  a  medical  device  for  the  non-invasive  treatment  of  vaginal  introital
laxity for improved sexual function, and for vaginal rejuvenation depending on the relevant country-specific clearance or approval
that it refers to as the Viveve System . The Viveve System consists of  three main components: a radiofrequency generator housed in
a table-top console; a reusable handpiece; and a single-use treatment tip. Single-use accessories (e.g. RF return pad, coupling fluid),
a foot pedal and a cryogen canister that can be used for approximately four  to five procedures are also included with the System.
The Company outsources the manufacture and repair of the Viveve System to a single contract manufacturer. Also, certain other
components and materials that comprise the device are currently manufactured by a single supplier or a limited number of suppliers.
A significant supply interruption or disruption in the operations of the contract manufacturer or these third-party  suppliers  would
adversely impact the production of our products for a substantial period of time, which could have a material adverse effect on our
business, financial condition, operating results and cash flows.

In North America, the Company sells its products primarily through a direct sales force to health care practitioners. Outside North
America, the Company sells through an extensive network of distribution partners. During the year ended December 31, 2017, two
distributors  together  accounted  for 35% of the Company’s revenue. During the year ended  December  31,  2016, three distributors
together accounted for 78% of the Company’s revenue.

There  are no  direct  sales  to  customers  that  accounted  for  more  than 10%  of  the  Company’s  revenue  during  the  years  ended
December 31, 2017 and 2016.

As of December 31, 2017, two distributors, collectively, accounted for  57 % of total accounts receivable, net. As of December 31,
2016, three distributors, collectively, accounted for 81% of total accounts receivable, net.

F-8

 
 
 
 
 
 
 
 
 
 
 
 
Accounts Receivable and Allowance for Doubtful Accounts

Accounts receivable are recorded at the invoiced amount and are not interest bearing. Our typical payment terms vary by region and
type of customer (distributor or physician). Occasionally, payment terms of up to  six months may be granted to customers with an
established history of collections without concessions. Should we grant payment terms greater than six months or terms that are not
in accordance with established history for similar arrangements, revenue would be recognized as payments become due and payable
assuming all other criteria for revenue recognition have been met. The Company maintains an allowance for doubtful accounts for
estimated losses resulting from the inability of its customers to make required payments. The Company makes ongoing assumptions
relating to the collectibility of its accounts receivable in its calculation of the allowance for doubtful accounts. In determining the
amount  of  the  allowance,  the  Company  makes  judgments  about  the  creditworthiness  of  customers  based  on  ongoing  credit
evaluations and assesses current economic trends affecting its customers that might impact the level of credit losses in the future
and result in different rates of bad debts than previously seen. The Company also considers its historical level of credit losses. The
allowance for doubtful accounts was $221,000 and zero as of December 31, 2017 and 2016, respectively.

Inventory

Inventory  is  stated  at  the  lower  of  cost  or net  realizable  value.  Inventory  as  of  December  31,  2017 consisted  of $1,990,000  of
finished goods and $400,000 of raw materials. Inventory as of December 31, 2016 consisted  of $2,506,000 of finished goods and
$181,000 of raw materials. Cost is determined on an actual cost basis on a first-in, first-out method. Lower of cost or net realizable
value is evaluated by considering obsolescence, excessive levels of inventory, deterioration and other factors. Adjustments to reduce
the  cost  of  inventory  to  its  net  realizable  value,  if  required,  are  made  for  estimated  excess,  obsolescence  or  impaired  inventory.
Excess  and  obsolete  inventory  is  charged  to  cost  of  revenue  and  a  new  lower-cost  basis  for  that  inventory  is  established  and
subsequent changes in facts and circumstances do not result in the restoration or increase in that newly established cost basis.

As  part  of  the  Company’s  normal  business,  the  Company  generally  utilizes  various  finished  goods  inventory  as  sales  demos  to
facilitate the sale of its products to prospective customers. The Company is amortizing these demos over an estimated useful life of
five years. The amortization of the demos is charged to selling, general and administrative expense and the demos are included in
the medical equipment line within the property and equipment, net balance on the consolidated balance sheets as of December 31,
2017 and 2016.

Property and Equipment, net

Property  and  equipment  are  stated  at  cost,  net  of  accumulated  depreciation  and  amortization.  Depreciation  of  property  and
equipment  is  computed  using  the  straight-line  method  over  their  estimated  useful  lives  of three 
to seven  years.  Leasehold
improvements  are  amortized  on  a  straight-line  basis  over  the  lesser  of  their  useful  lives  or  the  life  of  the  lease.  Upon  sale  or
retirement  of  assets,  the  cost  and  related  accumulated  depreciation  and  amortization  are  removed  from  the  balance  sheet  and  the
resulting gain or loss is reflected in operations. Maintenance and repairs are charged to operations as incurred.

Impairment of Long-Lived Assets

The  Company  reviews  long-lived  assets  for impairment  whenever  events  or  changes  in  circumstances  indicate  that  the  carrying
amount  of  an  asset  might not  be  recoverable.  When  such  an  event  occurs,  management  determines  whether  there  has  been  an
impairment  by  comparing  the  anticipated  undiscounted  future  net  cash  flows  to  the  related  asset’s  carrying  value.  If  an  asset  is
considered impaired, the asset is written down to fair value, which is determined based either on discounted cash flows or appraised
value, depending on the nature of the asset. The Company has not identified any such impairment losses to date.

Revenue Recognition

The Company recognizes revenue net of sales taxes from the sale of its products, the Viveve System, single-use treatment tips and
ancillary consumables. Revenue is recognized upon shipment, provided that persuasive evidence of an arrangement exists, the price
is  fixed  or  determinable  and  collection  of  the  resulting  receivable  is  reasonably  assured.  Sales  of  our  products  are  subject  to
regulatory requirements that vary from country to country. The Company has regulatory clearance, or can sell its products without a
clearance,  in  many  countries  throughout  the  world,  including  countries  within  the  following  regions:  North  America,  Latin
America, Europe, the Middle East and Asia Pacific.

F-9

 
 
 
 
 
 
  
 
 
 
 
 
 
The Company also sells a small number of extended service agreements on certain products for the period subsequent to the normal
one-year warranty provided with the original product sale. Revenue is recognized over the service agreement period. Revenue from
sale of such extended service agreements was immaterial for the years ended December 31, 2017 and 2016.

When  a  sales  agreement  involves  multiple  deliverables,  such  as  extended  warranties,  the  multiple  deliverables  are  evaluated  to
determine the units of accounting. Judgment is required to properly identify the accounting units of multiple element transactions
and the manner in which revenue is allocated among the accounting units. Judgments made, or changes to judgments made, may
significantly affect the timing or amount of revenue recognition.

Revenue related to the multiple deliverables is allocated to each unit of accounting using the selling price hierarchy. Consistent with
accounting guidance, the selling price is based upon vendor specific objective evidence (“VSOE”). If VSOE is not  available, third
party evidence (“TPE”) is used to establish the selling price. In the absence of VSOE or TPE, estimated selling price (“ESP”) is
used.  For  the  years  ended December  31,  2017 and 2016,  the  Company  has  used  ESP  to  calculate  the  relative  fair  value  of  the
deliverables.  The  Company  regularly  reviews  ESP  and  maintains  internal  controls  over  the  establishment  and  updates  of  these
estimates. There were no material changes to our estimates of ESP during the years reported on.

The Company does not provide its customers with a right of return.

Customer Advance Payments

From  time  to  time,  customers  will  pay  for  a  portion  of  the  products  ordered  in  advance.   Upon  receipt  of  such  payments,  the
Company records the customer advance payment as a component of accrued liabilities.  The Company will remove the customer
advance payment from accrued liabilities when revenue is recognized upon shipment of the products.

Investments in Unconsolidated Affiliates

The  Company  uses  the  equity  method  to  account  for  its  investments  in  entities  that  it  does not  control  but  have  the  ability  to
exercise significant influence over the investee. Equity method investments are recorded at original cost and adjusted periodically to
recognize (1) the proportionate share of the investees’ net income or losses after the date of investment, ( 2) additional contributions
made  and  dividends  or  distributions  received,  and  (3)  impairment  losses  resulting  from  adjustments  to  net  realizable  value.  The
Company  eliminates  all  intercompany  transactions  in  accounting  for  equity  method  investments.  The  Company  records  the
proportionate  share  of  the  investees’  net  income  or  losses  in  equity  in  earnings  of  unconsolidated  affiliates  on  the  consolidated
statements  of  operations. We  utilize  a three-month  lag  in  reporting  equity  income  from  our  investments,  adjusted  for  known
amounts and events, when the investee’s financial information is  not available timely or when the investee’s reporting period differs
from our reporting period.

The Company assesses the potential impairment of the equity method investments when indicators such as a history of operating
losses,  a  negative  earnings  and  cash  flow  outlook,  and  the  financial  condition  and  prospects  for  the  investee’s  business  segment
might  indicate  a  loss  in  value.  The  carrying  value  of  the  investments  is  reviewed  annually  for  changes  in  circumstances  or  the
occurrence of events that suggest the investment may not be recoverable. During the year ended December 31, 2017, no impairment
charges have been recorded.

Product Warranty

The Company’s  products  are  generally  subject  to  a  one-year  warranty,  which  provides  for  the  repair,  rework  or  replacement  of
products (at the Company’s option) that fail to perform within stated specification. The Company has assessed the historical claims
and, to date, product warranty claims have not been significant.

F-10

 
 
 
 
 
 
 
 
 
 
 
 
 
Shipping and Handling Costs

The Company includes amounts billed for shipping and handling in revenue and shipping and handling costs in cost of revenue.

Advertising Costs

Advertising costs are charged to selling, general and administrative expenses as incurred. Advertising expenses, which are recorded
in selling, general and administrative expenses, were immaterial for the years ended December 31, 2017 and 2016.

Research and Development

Research and development costs are charged to operations as incurred. Research and development costs include, but are not limited
to, payroll and personnel expenses, prototype materials, laboratory supplies, consulting costs, and allocated overhead, including rent,
equipment depreciation, and utilities.

Income Taxes

The  provision  for  income  taxes  is  determined  using  the  asset  and  liability  approach  of  accounting  for  income  taxes.  Under  this
approach, deferred taxes represent the future tax consequences expected to occur when the reported amounts of assets and liabilities
are recovered or paid. The provision for income taxes represents income taxes paid or payable for the current year plus the change
in deferred taxes during the year. Deferred taxes result from differences between the financial and tax basis of the Company’s assets
and liabilities and are adjusted for changes in tax rates and tax laws when changes are enacted. Valuation allowances are recorded
to reduce deferred tax assets when it is more likely than not that a tax benefit will not be realized.

The Company must assess the likelihood that the Company ’s deferred tax assets will be recovered from future taxable income, and
to  the  extent  the  Company  believes  that  recovery  is not  likely,  the  Company  establishes  a  valuation  allowance.  Management
judgment is required in determining the Company’s provision for income taxes, deferred tax assets and liabilities, and any valuation
allowance recorded against the net deferred tax assets. The Company recorded a full valuation allowance as of December 31, 2017
and 2016.  Based  on  the  available  evidence,  the  Company  believes  it  is  more  likely  than  not  that  it  will not  be  able  to  utilize  its
deferred tax assets in the future. The Company intends to maintain valuation allowances until sufficient evidence exists to support
the reversal of such valuation allowances. The Company makes estimates and judgments about its future taxable income that are
based  on  assumptions  that  are  consistent  with  its  plans.  Should  the  actual  amounts  differ  from  the  Company’s  estimates,  the
carrying value of the Company’s deferred tax assets could be materially impacted.

The Company recognizes in the financial statements the impact of a tax position, if that position is more likely than  not of being
sustained  on  audit,  based  on  the  technical  merits  of  the  position.  The  Company’s  policy  is  to  recognize  interest  and  penalties
accrued on any unrecognized tax benefits as a component of income tax expense. The Company does not believe there are any tax
positions  for  which  it  is  reasonably  possible  that  the  total  amounts  of  unrecognized  tax  benefits  will  significantly  increase  or
decrease within 12 months of the reporting date.

Accounting for Stock-Based Compensation

Share-based compensation cost is measured at grant date, based on the fair value of the award, and is recognized as expense over
the  employee’s  service  period.  The  Company  recognizes  compensation  expense  on  a  straight-line  basis  over  the  requisite  service
period of the award.

F-11

 
 
 
 
 
  
 
 
 
 
 
 
 
 
We determined that the Black-Scholes option pricing  model is the most appropriate method for determining the estimated fair value
for stock options and purchase rights under the employee stock purchase plan. The Black-Scholes option pricing model requires the
use  of  highly  subjective  and  complex  assumptions  which  determine  the  fair  value  of  share-based  awards,  including  the  option’s
expected term and the price volatility of the underlying stock.

Equity  instruments  issued  to  nonemployees  are  recorded  at  their  fair  value  on  the  measurement  date  and  are  subje ct  to  periodic
adjustment as the underlying equity instruments vest.

Comprehensive Loss

Comprehensive  loss  represents  the  changes  in  equity  of  an  enterprise,  other  than  those  resulting  from  stockholder  transactions.
Accordingly,  comprehensive  loss may include  certain  changes  in  equity  that  are  excluded  from  net  loss.  For  the  years  ended
December 31, 2017 and 2016, the Company’s comprehensive loss is the same as its net loss. 

Net Loss per Share

The Company’s basic net loss per share is calculated by dividing the net loss by the weighted average number of shares of common
stock outstanding for the period. The diluted net loss per share is computed by giving effect to all potentially dilutive common stock
equivalents outstanding during the period. For purposes of this calculation, stock options and warrants to purchase common stock
and restricted common stock awards are considered common stock equivalents. For periods in which the Company has reported net
losses, diluted net loss per share is the same as basic net loss per share, since dilutive common shares are not assumed to have been
issued if their effect is anti-dilutive.

The following securities were excluded from the calculation of net loss per share because the inclusion would be anti-dilutive. 

Stock options to purchase common stock
Warrants to purchase common stock
Restricted common stock awards

Recently Issued and Adopted Accounting Standards

Year Ended
December 31,

2017

2016

2,694,224     
642,622     
10,000     

1,909,764 
425,274 
58,155 

I n May  2014, as  part  of  its  ongoing  efforts  to  assist  in  the  convergence  of  U.S.  GAAP  and  International  Financial  Reporting
Standards (“IFRS”), the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”)  2014-09,
“Revenue from Contracts with Customers (Topic 606)” which created Accounting Standards Codification Topic  606  (“ASC 606”).
The new guidance sets forth a new five-step revenue recognition model which replaces the prior revenue recognition guidance in its
entirety  and  is  intended  to  eliminate  numerous  industry-specific  pieces  of  revenue  recognition  guidance  that  have  historically
existed in U.S. GAAP. The underlying principle of the new standard is that a business or other organization will recognize revenue
to  depict  the  transfer  of  promised  goods  or  services  to  customers  in  an  amount  that  reflects  what  it  expects  in  exchange  for  the
goods or services. The standard also requires more detailed disclosures and provides additional guidance for transactions that were
not  addressed  completely  in  the  prior  accounting  guidance.  The  ASU  provides  alternative  methods  of  initial  adoption  and  is
effective for annual and interim periods beginning after December 15, 2017. The FASB has issued several updates to the standard
which i) defer the original effective date from January 1, 2017 to January 1, 2018, while allowing for early adoption as of January 1,
2017 (ASU 2015-14); ii) clarify the application of the principal versus agent guidance (ASU 2016-08); iii) clarify the guidance on
inconsequential and perfunctory promises and licensing (ASU 2016-10); and clarify the guidance on certain sections of the guidance
providing technical corrections and improvements (ASU 2016-10). In May 2016, the  FASB  issued ASU  2016-12, “Revenue from
Contracts with Customers (Topic 606) Narrow-Scope Improvements and Practical Expedients”, to address certain narrow aspects of
the  guidance  including  collectibility  criterion,  collection  of  sales  taxes  from  customers,  noncash  consideration,  contract
modifications and completed contracts. This issuance does not change the core principle of the guidance in the initial topic issued in
May 2014.

F-12

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
     
       
 
   
   
   
 
 
 
The  Company  did not  early  adopt  this  guidance,  and  accordingly,  will  adopt  this  new  standard  effective  January  1,  2018. The
guidance  permits  the  use  of  either  a  full  retrospective  or  modified  retrospective  transition  method  as  of  the  adoption  date.  The
Company currently plans to adopt the standard using the modified retrospective approach.  Should the adoption of ASC 606 under
the modified retrospective method result in the deferral of revenue previously recognized, or the recognition of revenue previously
deferred under ASC 605 beyond January 1, 2018, the Company would record a cumulative catch-up adjustment at  January 1, 2018.

As part of its preliminary evaluation, the Company has also considered the impact of the guidance in ASC  340-40, “Other Assets
and Deferred Costs; Contracts with Customers”, with respect to capitalization and amortization of incremental costs of obtaining a
contract.  This  guidance,  requires  the  capitalization  of  all  incremental  costs  that  the  Company  incurs  to  obtain  a  contract  with  a
customer that it would not have incurred if the contract had not been obtained, provided the Company expects to recover the costs.
The Company does not believe that it will not be required to capitalize any additional costs of obtaining the contract or additional
sales commissions.

The Company has set up a team for the implementation of the new revenue recognition accounting standard. Based on preliminary
analysis, the Company expects that the new standard will not significantly impact the recognition of product sales given their point
of  sale  nature.  The  Company  is  still  in  the  process  of  evaluating  its  arrangements  with  distributors  as  well  as  those  related  to
extended warranties under ASC 606.

I n July  2015, the  FASB  issued  ASU  2015-11,  “Simplifying  the  Measurement  of  Inventory”  (“ASU 2015-11”).  ASU 2015-11
requires  that  an  entity  should  measure  inventory  within  the  scope  of  this  pronouncement  at  the  lower  of  cost  and  net  realizable
value.  Net  realizable  value  is  the  estimated  selling  prices  in  the  ordinary  course  of  business,  less  reasonably  predictable  costs  of
completion, disposal, and transportation. The pronouncement does not apply to inventory that is being measured using the last-in,
first-out  (“LIFO”)  method  or  the  retail  inventory  method.  Subsequent  measurement  is  unchanged  for  inventory  measured  using
LIFO  or  the  retail  inventory  method. ASU  2015-11  was  effective  for  the  Company’s  fiscal  year  beginning  January 1, 2017.  The
adoption did not have a significant impact on the consolidated financial statements.

In February  2016, the  FASB  issued ASU  2016-02, “Leases  (Topic  842)”.  Under  this  guidance,  an  entity  is  required  to  recognize
right-of-use assets and lease liabilities on its balance sheet and disclose key information about leasing arrangements. This guidance
offers  specific  accounting  guidance  for  a  lessee,  a  lessor  and  sale  and  leaseback  transactions.  Lessees  and  lessors  are  required  to
disclose qualitative and quantitative information about leasing arrangements to enable a user of the financial statements to assess
the  amount,  timing  and  uncertainty  of  cash  flows  arising  from  leases.  This  guidance  is  effective  for  annual  reporting  periods
beginning  after December  15,  2018, including  interim  periods  within  the  reporting  period,  and  requires  a  modified  retrospective
adoption, with early adoption permitted. We are currently evaluating the effect of the adoption of this guidance on our consolidated
financial statements.

In March  2016, the  FASB  issued ASU  2016-09, “Compensation  –  Stock  Compensation  (Topic 718):  Improvements  to  Employee
Share-Based  Payment Accounting”.  This  guidance  identifies  areas  for  simplification  involving  several  aspects  of  accounting  for
share-based payment transactions, including the income tax consequences, classification of awards as either equity or liabilities, an
option  to  recognize  gross  stock  compensation  expense  with  actual  forfeitures  recognized  as  they  occur,  as  well  as  certain
classifications on the statement of cash flows. We adopted this standard on  January 1, 2017 and have elected to continue to estimate
forfeitures expected to occur to determine the amount of compensation cost to be recognized in each period. The adoption did not
have a significant impact on the consolidated financial statements.

F-13

 
 
 
 
 
 
 
 
In August 2016, the FASB issued ASU  No. 2016-15, “Statement of Cash Flows, Classification of Certain Cash Receipts and Cash
Payments (Topic 230)”. This guidance addresses specific cash flow issues with the objective of reducing the diversity in practice for
the treatment of these issues. The areas identified include: debt prepayment or debt extinguishment costs; settlement of zero-coupon
debt instruments; contingent consideration payments made after a business combination; proceeds from the settlement of insurance
claims;  proceeds  from  the  settlement  of  corporate-owned  life  insurance  policies;  distributions  received  from  equity  method
investees; beneficial interests in securitization transactions and application of the predominance principle with respect to separately
identifiable  cash  flows.  This  guidance  is  effective  for  annual  reporting  periods  beginning  after December  15,  2017, including
interim periods within that reporting period, with early adoption permitted. We plan to adopt this guidance as of January 1, 2018
and believe the adoption of the guidance will not have a significant impact on the consolidated financial statements.

In August  2016, the  FASB  issued  ASU  No. 2016-18, “Statement  of  Cash  Flows,  Restricted  Cash  (Topic 230)”.  This  guidance
requires that a statement of cash flows explain the total change during the period of cash, cash equivalents, and amounts generally
described  as  restricted  cash  or  restricted  cash  equivalents. Amounts  described  as  restricted  cash  and  restricted  cash  equivalents
should  be  included  with  cash  and  cash  equivalents  when  reconciling  the  beginning  of  period  and  end  of  period  to  total  amounts
shown on the statement of cash flows. This guidance is effective for annual reporting periods beginning after December 15, 2017,
including interim periods within that reporting period, with early adoption permitted. We plan to adopt this guidance as of  January
1, 2018 and believe the adoption of the guidance will not have a significant impact on the consolidated financial statements.

In May  2017, the  FASB  issued  ASU  No.  2017-09,  “Compensation  -  Stock  Compensation  (Topic 718),  Scope  of  Modification
Accounting”.  This  pronouncement  provides  guidance  about  which  changes  to  the  terms  or  conditions  of  a  share-based  payment
award may require  an  entity  to  apply  modification  accounting  under  Topic 718.    This  guidance  is  effective  for  annual  reporting
periods beginning after December 15, 2017, including interim periods within that reporting period, with early adoption permitted.
We plan to adopt this guidance as of  January 1, 2018 and believe the adoption of the guidance will not have a significant impact on
the consolidated financial statements. 

We  have  reviewed  other  recent  accounting  pronouncements  and  concluded  they  are  either  not  applicable  to  the  business,  or no
material effect is expected on the consolidated financial statements as a result of future adoption.

3. Fair Value Measurements

The  Company  recognizes  and  discloses  the  fair  value  of  its  assets  and  liabilities  using  a  hierarchy  that  prioritizes  the  inputs  to
valuation techniques used to measure fair value. The hierarchy gives the highest priority to valuations based upon unadjusted quoted
prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to valuations based upon
unobservable  inputs  that  are  significant  to  the  valuation  (Level 3  measurements).  Each  level  of  input  has  different  levels  of
subjectivity and difficulty involved in determining fair value.

Level 1

Level 2

Level 3

Inputs  used  to  measure  fair  value  are  unadjusted  quoted  prices  that  are  available  in  active
markets for the identical assets or liabilities as of the reporting date. Therefore, determining
fair  value  for  Level 1  investments  generally  does not require significant judgment, and the
estimation is not difficult.

Pricing  is  provided  by third  party  sources  of  market  information  obtained  through
investment advisors. The Company does not adjust for or apply any additional assumptions
or estimates to the pricing information received from its advisors.

Inputs used to measure fair value are unobservable inputs that are supported by little or no
market  activity  and  reflect  the  use  of  significant  management  judgment.  These  values  are
generally determined using pricing models for which the assumptions utilize management’s
estimates  of  market  participant  assumptions.  The  determination  of  fair  value  for  Level 3
instruments involves the most management judgment and subjectivity.

F-14

 
 
 
 
 
  
 
 
  
 
 
 
 
 
  
 
 
Assets and liabilities measured at fair value are classified in their entirety based on the lowest level of input that is significant to the
fair  value  measurement.  The  Company’s  assessment  of  the  significance  of  a  particular  input  to  the  fair  value  measurement  in  its
entirety requires management to make judgments and consider factors specific to the asset or liability.

There were no financial instruments that were measured at fair value on a recurring basis as of December 31, 2017 and 2016.

The carrying amounts of the Company ’s financial assets and liabilities, including cash and cash equivalents, accounts receivable,
accounts payable, and accrued expenses as of December 31, 2017 and 2016 approximate fair value because of the short maturity of
these instruments. Based on borrowing rates currently available to the Company for loans with similar terms, the carrying value of
the note payable approximates fair value.

There were no changes in valuation techniques from prior periods.

4. Property and Equipment, Net

Property and equipment, net, consisted of the following as of  December 31, 2017 and 2016 (in thousands):

Medical equipment
Computer equipment
Leasehold Improvements
Furniture and fixtures

Less: Accumulated depreciation and amortization
Property and equipment, net

Life
(in years)

December 31,

2017

2016

5
3
3
7

    $

     $

1,299    $
193     
200     
340     
2,032     
(729)   
1,303    $

657 
83 
- 
57 
797 
(314)
483 

Depreciation and amortization expense for the years ended December 31, 2017 and 2016 was $449,000 and $111,000, respectively.

5.

Investment in Limited Liability Company

On August  8,  2017, the  Company  entered  into  an  exclusive  Distributorship Agreement  (the  “ Distributorship Agreement”)  with
InControl  Medical,  LLC  (“ICM”),  a  Wisconsin  limited  liability  company  focused  on  women's  health,  pursuant  to  which  the
Company will directly market, promote, distribute and sell ICM’s products to licensed medical professional offices and hospitals.

Under the terms of the Distributorship Agreement, ICM agreed to  not directly or indirectly appoint or authorize any third party to
market, promote,  distribute  or  sell  any  of  the  licensed  products  to  any  licensed  medical  professional  offices  and  hospitals  in  the
United States. In exchange, the Company agreed to not market, promote, distribute or sell (or contract to do so) any product which
substantially  replicates  all  or  almost  all  of  the  key  features  of  the  licensed  products.  The  Company  has  a  minimum  purchase
requirement  to  purchase  a  certain  quantity  of  ICM  products  per  month  during  the  term  of  this  Distributorship  Agreement.  In
addition, the parties agreed to certain mutual marketing obligations to promote sales of the licensed products. As of December 31,
2017, the Company has purchased approximately 1,200 units of ICM products. The Company paid ICM approximately $94,000 for
product related costs during the year ended December 31, 2017.   

F-15

 
 
 
 
 
  
 
 
 
 
 
   
 
 
 
   
   
 
 
   
       
       
 
 
 
     
 
     
 
     
 
 
      
 
      
 
 
 
 
 
 
 
In connection with the Distributorship Agreement, the Company also entered into a Membership Unit Subscription Agreement with
ICM and the associated limited liability company operating agreement of ICM, pursuant to which the Company invested $2,500,000
in, and acquired membership units of, ICM. This investment has been recorded in investment in a limited liability company in the
consolidated  balance  sheets.  The  Company  used  the  equity  method  to  account  for  the  investment  in  ICM  because  the  Company
does not  control  it  but  has  the  ability  to  exercise  significant  influence  over  it. As  of  December  31,  2017, the  Company  owns
approximately 11% ownership interest in ICM. The Company recognizes its allocated portion of ICM’s results of operations on a
three-month lag due to the timing of financial information. For the year ended  December 31, 2017, the allocated results from ICM’s
operations were immaterial.

 6. Accrued Liabilities

Accrued liabilities consisted of the following as of  December 31, 2017 and 2016 (in thousands):

Accrued bonuses
Accrued sales commission
Accrued payroll and other related expenses
Accrued professional fees
Accrued interest
Accrued sales & use tax
Other accruals

Total accrued liabilities

7. Note Payable

  December 31,

    December 31,

2017

2016

  $

  $

1,597    $
1,067     
488     
562     
447     
149     
295     
4,605    $

1,102 
115 
249 
483 
65 
39 
133 
2,186 

On June  20,  2016, the  Company  entered  into  a  Loan  and  Security Agreement,  as  amended January  13,  2017  (the  “2016  Loan
Agreement”) with Western Alliance Bank (“WAB”), pursuant to which WAB agreed to loan the Company up to an aggregate of
$10,000,000 payable in two tranches of $7,500,000  and $2,500,000. The funding conditions for both tranches were satisfied as of
the  closing  date,  and  therefore,  the  aggregate  principal  amount  of $10,000,000  was  provided  on June  20,  2016. The  terms  of  the
loan  also  required  the  Company  to  meet  certain  financial  and  other  covenants  in  connection  with  the 2016  Loan Agreement.  In
addition to all outstanding principal and accrued interest on the term loan, the terms of the loan required the Company to pay a final
payment fee equal to 4.00% of the original principal amount of the term loan. All borrowings under the  2016 Loan Agreement were
collateralized  by  substantially  all  of  the  Company’s  assets,  including  intellectual  property.  The  outstanding  principal  balance  and
accrued interest related to this note payable were repaid in May 2017 (see discussion below).

In connection with the 2016 Loan Agreement, the Company issued a 10-year warrant to WAB to purchase a total of 100,402 shares
of the Company’s common stock at an exercise price of $4.98 per share (See Note 9).

On May  22,  2017, the  Company  entered  into  a  Term  Loan Agreement  (the  “ 2017  Loan Agreement”)  with  affiliates  of  CRG  LP
(“CRG”).  The  credit  facility  consists  of $20,000,000  drawn  at  closing  and  access  to  additional  funding  of  up  to  an  aggregate  of
$10,000,000  for  a  total  of $30,000,000  available  under  the  credit  facility.  On December  29,  2017, the  Company  accessed  the
remaining $10,000,000 available under the CRG credit facility.

A portion of the initial loan proceeds were used to repay all of the amounts owed by the Company under its  2016 Loan Agreement
with  WAB.  The  remainder  of  the  loan  proceeds  (after  deducting  loan  origination  costs  and  other  fees  and  expenses  incurred  in
connection  with  the 2017  Loan Agreement),  plus  any  additional  amounts  that  may be  borrowed  in  the  future,  will  be  used  for
general corporate purposes and working capital.

F-16

 
 
 
 
 
 
 
 
 
 
 
   
 
 
   
 
     
 
 
   
   
   
   
   
   
 
 
 
 
 
 
 
The 2017 Loan Agreement has a six-year term with four years of interest-only payments after which quarterly principal and interest
payments will be due through the maturity date. Amounts borrowed under the  2017 Loan Agreement accrue interest at an annual
fixed rate of 12.50%, 4.0% of which may, at the election of the Company, be paid in-kind during the interest-only period by adding
such  accrued  amount  to  the  principal  loan  amount  each  quarter.  During  the  year  ended December  31,  2017, the  Company  paid
interest  in-kind  of $495,000  which  was  added  to  the  total  outstanding  principal  loan  amount  as  of December  31,  2017. The
Company  is  also  required  to  pay  CRG  a  final  payment  fee  upon  repayment  of  the  loans  in  full  equal  to 5%  of  the  sum  of  the
aggregate  principal  amount  plus  the  deferred  interest  added  to  the  principal  loan  amount  during  the  interest-only  period.  The
Company accounts for the final payment fee by accruing the fee over the term of the loan using the effective interest rate method.
As  of December  31,  2017, interest  accrued  related  to  the  final  payment  fee  in  the  amount  of $132,000  was  included  in  other
noncurrent liabilities in the consolidated balance sheets.

The Company may prepay all or a portion of the outstanding principal and accrued unpaid int erest under the 2017 Loan Agreement
at any time upon prior notice to CRG, subject to a prepayment fee during the first five years of the term (which reduces each year)
and no prepayment fee thereafter.

As security for its obligations under the 2017 Loan Ag reement, the Company entered into security agreements with CRG whereby
the Company granted CRG a lien on substantially all of the Company’s assets, including intellectual property.

The terms of the 2017 Loan Agreement also require the Company to meet certain financial and other covenants. These covenants
require  the  Company  to  maintain  cash  and  cash  equivalents  of $2.0  million  and,  each  year  through  the  end  of 2022,  to  meet  a
minimum total annual revenue threshold. In the event that the Company does not meet the minimum total annual revenue threshold
for a particular year, then the Company can retroactively cure the shortfall by either issuing additional equity in exchange for cash
or incurring certain additional permitted indebtedness, in each case, in an amount equal to 2.0 times the shortfall. Any such amounts
shall be applied to prepay the loans. The 2017 Loan Agreement also contains customary affirmative and negative covenants for a
credit  facility  of  this  size  and  type,  including  covenants  that  limit  or  restrict  the  Company’s  ability  to,  among  other  things,  incur
indebtedness, grant liens, merge or consolidate, dispose of assets, make investments, make acquisitions, enter into transactions with
affiliates, pay dividends or make distributions, license intellectual property rights on an exclusive basis or repurchase stock, in each
case subject to customary exceptions. As of December 31, 2017, the Company was in compliance with all covenants.

In  connection  with  the 2017 Loan Agreement, the Company issued tw o 10-year  warrants  to  CRG  to  purchase  a  total  of 222,049
shares of the Company’s common stock at an exercise price of $9.50 per share (See Note 9). 

As of December 31, 2017, future minimum payments under the note payable are as follows (in thousands):

Year Ending December 31,
2018
2019
2020
2021
2022
Thereafter

Total payments

Less: Amount representing interest

Present value of obligations

Less: Unamortized debt discount

Note payable, noncurrent portion

F-17

  $

  $

2,668 
2,778 
2,901 
16,672 
19,306 
6,221 
50,546 
(20,051)
30,495 
(1,547)
28,948 

 
 
 
 
 
 
 
 
     
 
   
   
   
   
   
   
   
   
   
 
8. Commitments and Contingencies

Operating Lease

In January 2012, the Company entered into a lease agreement for office and laboratory facilities in Sunnyvale, California. The lease
agreement, as amended in September 2016, commenced in March 2012 and will terminate in March 2018.

On February  1,  2017, the  Company  entered  into  a  sublease  agreement  (the  “Sublease”)  for  approximately 12,400  square  feet  of
building  space  for  the  relocation  of  the  Company’s  corporate  headquarters  to  Englewood,  Colorado  (the  “Sublease  Premises”),
which  was  effective  as  of January  26,  2017. The  lease  term  commenced  on June  1,  2017 and  will  terminate  in May  2020. We
relocated our corporate headquarters from Sunnyvale, California to Englewood, Colorado in June 2017.

The monthly base rent under the Sublease is equal to $20.50 per rentable square foot of the Sublease Premises during the first year.
The  monthly  base  rent  is  equal  to $21.12  and $21.75 per  rentable  square  foot  during  the second  and third  years,  respectively.  In
connection with the execution of the Sublease, the Company also agreed to pay a security deposit of approximately $22,000. The
Company is entitled to an allowance of approximately $88,000 for certain tenant improvements relating to the engineering, design
and construction of the Sublease Premises. 

Rent expense for the years ended  December 31, 2017 and 2016 was $442,000 and $236,000, respectively.

As of December 31, 2017, future minimum payments under the lease are as follows (in thousands): 

Year Ending December 31,
2018
2019
2020

Total minimum lease payments

Indemnification Agreements

  $

  $

338 
264 
112 
714 

The  Company  enters  into  standard  indemnification  arrangements  in  the  ordinary  course  of  business.  Pursuant  to  these
arrangements,  the  Company  indemnifies,  holds  harmless  and  agrees  to  reimburse  the  indemnified  parties  for  losses  suffered  or
incurred  by  the  indemnified  party,  in  connection  with  performance  of  services  within  the  scope  of  the  agreement,  breach  of  the
agreement by the Company, or noncompliance of regulations or laws by the Company, in all cases provided the indemnified party
has not breached the agreement and/or the loss is  not attributable to the indemnified party’s negligence or willful malfeasance. The
term  of  these  indemnification  agreements  is  generally  perpetual  any  time  after  the  execution  of  the  agreement.  The  maximum
potential  amount  of  future  payments  the  Company  could  be  required  to  make  under  these  arrangements  is not  determinable.  The
Company has never incurred costs to defend lawsuits or settle claims related to these indemnification agreements. As a result, the
Company believes the estimated fair value of these agreements is minimal.

Loss Contingencies

The  Company  is  or  has  been  subject  to  proceedings,  lawsuits  and  other  claims  arising  in  the  ordinary  course  of  business.  The
Company evaluates contingent liabilities, including threatened or pending litigation, for potential losses. If the potential loss from
any  claim  or  legal  proceeding  is  considered  probable  and  the  amount  can  be  estimated,  the  Company  accrues  a  liability  for  the
estimated  loss.  Because  of  uncertainties  related  to  these  matters,  accruals  are  based  upon  the  best  information  available.  For
potential losses for which there is a reasonable possibility (meaning the likelihood is more than remote but less than probable) that a
loss exists, the Company will disclose an estimate of the potential loss or range of such potential loss or include a statement that an
estimate of the potential loss cannot be made. As additional information becomes available, the Company reassesses the potential
liability  related  to  pending  claims  and  litigation  and may revise  its  estimates,  which  could  materially  impact  the  consolidated
financial statements. Management does not believe that the outcome of any outstanding legal matters will have a material adverse
effect on the Company's consolidated financial position, results of operations and cash flows.

Legal Proceedings

On March  11,  2016, the  Company  filed  a  demand  for Arbitration  with  the American Arbitration Association  ("AAA")  against  a
former  employee  asserting  common  law  and  statutory  negligence  claims  against  the  former  employee  arising  from  the  former
employee's  negligent  performance  of  certain  work  duties.  The  demand  seeks  damages  for  lost  profits,  along  with  attorney's  fees,
interest,  and  costs.  The  former  employee  filed  a  counterclaim  in  the  proceeding,  alleging  discrimination,  retaliation,  wrongful
termination, and various claims for alleged wage and hour violations under the California Labor Code, stemming from the cessation
of her employment with the Company. The former employee seeks damages for lost wages, punitive damages, statutory penalties,
injunctive relief, and attorney’s fees, interest and costs.

On October  21,  2016, Viveve  filed  a  lawsuit  against  ThermiGen  LLC,  ThermiAesthetics  LLC,  and  Dr. Alinsod,  in  the  Eastern
District  of  Texas  alleging  infringement  of  Viveve ’s  U.S.  Patent  Number 8,961,511  (the “‘511  patent”).  The  lawsuit  alleges
infringement  based  on  Defendants  use  and/or  sale  of  the  ThermiVa  system  and  ThermiVa  procedure.  Viveve  is  seeking  an
injunction and damages.

F-18

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
9. Common Stock

The  Company  established,  through  the  filing  of  a  prospectus  supplement  to  its  shelf  registration  statement  on  Form  S-3  (filed
November 8, 2017), an “at-the-market” equity offering program under which the Company  may offer and sell, from time-to-time,
up to $25,000,000 aggregate offering price of shares of its common stock (the “November 2017 ATM  Facility”). As  of  December
31,  2017, the  Company  has  sold 59,249  shares  of  common  stock  under  the November  2017 ATM  Facility  for  net  proceeds  of
approximately $125,000.

On May  19,  2017, the  Company  issued 35,000 restricted shares of its common stock at a value of $7.42 a share, or an aggregate
value of approximately $260,000.

On March  22,  2017, in  connection  with  the  closing  of  the March  2017 Offering,  we  issued  an  aggregate  of 8,625,000  shares  of
common  stock,  including  the  exercise  of  the  underwriters’  overallotment  option,  at  a  public  offering  price  of $4.00  per  share  for
gross  proceeds  of  approximately $34,500,000.  The  net  proceeds  to  the  Company,  after  the  deduction  of  underwriting  discounts,
commissions and other offering expenses, were approximately $31,440,000.

On June 17, 2016, in connection with the closing of the June 2016 Offering, we issued an aggregate of 3,105,000 shares of common
stock, including  the  exercise  of  the  underwriters’  overallotment  option,  at  a  public  offering  price  of  $5.00  per  share  for  gross
proceeds  of  approximately $15,525,000.  The  net  proceeds  to  the  Company,  after  the  deduction  of  underwriting  discounts,
commissions and other offering expenses, were approximately $13,886,000.

Warrants for Common Stock

As of December 31, 2017, outstanding warrants to purchase shares of common stock were as follows: 

Issuance Date

Exercisable
for

Expiration
Date

Exercise
Price

September 2014
October 2014

November 2014
February 2015
March 2015
May 2015
May 2015
December 2015
April 2016
May 2016
June 2016
May 2017

  Common Shares  
  $
  Common Shares   October 13, 2019   $

September 23,
2019

November 12,
2019

  Common Shares  
  $
  Common Shares   February 17, 2025   $
  $
  Common Shares   March 26, 2025
  Common Shares   May 12, 2025
  $
  $
  Common Shares   May 17, 2020
  Common Shares   December 16, 2025  $
  $
  Common Shares   April 1, 2026
  $
  Common Shares   May 11, 2021
  $
  Common Shares   June 20, 2026
  $
  Common Shares   May 25, 2027

F-19

Number of
Shares
Outstanding
Under
Warrants

4.24     
4.24     

4.24     
4.00     
2.72     
4.24     
4.24     
5.60     
6.08     
7.74     
4.98     
9.50     

86,831 
29,000 

12,500 
75,697 
1,454 
36,229 
21,585 
26,875 
25,000 
5,000 
100,402 
222,049 
642,622 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
   
 
 
 
 
 
 
   
 
   
 
 
 
 
 
 
   
 
   
 
 
 
 
 
   
 
 
 
 
   
 
 
   
   
   
 
       
 
 
   
   
   
 
     
 
In connection with the Loan and Security Agreement entered into on  September 30, 2014, as amended on February 19, 2015, May
14,  2015, November  30,  2015 and March  18,  2016  (collectively,  the  “2014  Loan Agreement”),  with  Pacific  Western  Bank  (as
successor in interest by merger to Square 1 Bank), the Company issued a warrant to purchase a total of 58,962 shares of common
stock  at  an  exercise  price  of $4.24 per share. The fair value of the warrant was recorded as debt  issuance  costs,  presented  in  the
consolidated  balance  sheets  as  a  deduction  from  the  carrying  amount  of  the  note  payable,  and  was  being  amortized  to  interest
expense  over  the  loan  term.  The  outstanding  indebtedness  was  repaid  in June  2016 from  the  proceeds  of  the  new  term  loan  in
connection with the 2016 Loan Agreement and the remaining unamortized balance of debt issuance costs was recorded to interest
expense  for  the  quarter  ended June  30,  2016. During  the  year  ended December  31,  2016, the  Company  recorded $387,000,  of
interest expense relating to the debt issuance costs. The warrant was exercised on a cashless basis in August  2016 and 17,295 net
shares were issued.

In conjunction with the second amendment to the 2014 Loan Agreement in May 2015, the Company issued a warrant to the lender
to purchase a total of 3,125 shares of common stock at an exercise price of $2.96 per share. The debt issuance costs for this warrant
were fully amortized as of September 30, 2015. The warrant was exercised on a cashless basis in July 2016 and 885 net shares of
common stock were issued.

In connection with the 2016 Loan Agreement, the Company issued a warrant to purchase a total of 100,402 shares of common stock
at  an  exercise  price  of $4.98  per  share.  The  Company  determined  the  fair  value  of  the  warrant  on  the  date  of   issuance  to  be
$350,000. The fair value along with legal fees totaling $90,000, was recorded as debt issuance costs and was amortized to interest
expense  over  the  loan  term.  The  debt  issuance  costs  were  presented  in  the  consolidated  balance  sheet  as  a  deduction  from  the
carrying amount of the note payable. The outstanding indebtedness was repaid in May 2017 from the proceeds of the new term loan
in connection with the 2017 Loan Agreement and the remaining unamortized balance of debt issuance costs was recorded to interest
expense  for  the  quarter  ended June  30,  2017. During  the  years  ended December  31,  2017 and 2016,  the  Company  recorded
$371,000 and $69,000, respectively, of interest expense relating to the debt issuance costs .

In connection with the 2017 Loan Agreement, the Company issued warrants to purchase a total of 222,049, shares of common stock
at an exercise price of $9.50 per share. The warrants have a contractual life of ten years and are exercisable immediately in whole or
in  part.  The  Company  determined  the  fair  value  of  the  warrants  on  the  date  of  issuance  to  be $940,000  using  the  Black-Scholes
option  pricing  model. Assumptions  used  were  dividend  yield  of 0%,  volatility  of 55.1%,  risk  free  interest  rate  of 2.25%  and  a
contractual life of ten years. The fair value of the warrants along with financing and legal fees totaling $790,000, are recorded as
debt issuance costs and presented in the consolidated balance sheets as a deduction from the carrying amount of the note payable.
The  debt  issuance  costs  are  amortized  to  interest  expense  over  the  loan  term.  During  the  year  ended December  31,  2017, the
Company  recorded $183,000  of  interest  expense  relating  to  the  debt  issuance  costs  using  the  effective  interest  method. As  of
December 31, 2017, the unamortized debt discount was  $1,547,000.

A  total  of 4,701  and 25,268  shares,  issuable  pursuant  to  warrants  issued  in  connection  with  a  private  offering  on September  30,
2014, were issued in connection with the exercise of warrants during the years ended December 31, 2017 and 2016, respectively.

No  shares  issuable  pursuant  to  warrants  have  been  cancelled  during  the year  ended December  31,  2017. A  total  of 1,094  shares
issuable pursuant to warrants issued to two vendors in October 2014 were  cancelled  during  the  year  ended December  31,  2016 as
the milestones related to these shares were not achieved.

The total stock-based compensation expense related to warrants issued was zero  and $162,000  for  the  years  ended December 31,
2017 and 2016, respectively.

10. Summary of Stock Options

Stock Option Plans

The Company has issued equity awards in the form of stock options and restricted stock awards from three employee benefit plans.
The plans include the Company’s 2005 Stock Incentive Plan (the “2005 Plan”), the Viveve Amended and Restated  2006 Stock Plan
(the “2006 Plan”) and the Company’s Amended and Restated 2013 Stock Option and Incentive Plan (the “2013 Plan”).

F-20

 
 
 
 
 
 
 
 
 
 
 
 
 
There are currently no outstanding stock option awards issued from the 2005 Plan and no shares are available for future awards.

The 2006 Plan was adopted by the board of directors of Viveve, Inc.  and was terminated in conjunction with the merger that took
place on September 23, 2014 between PLC Systems Inc., Viveve, Inc. and PLC Systems Acquisition Corp. (the “Merger”). Prior to
the Merger, the board of directors voted to accelerate the vesting of all unvested options that were outstanding as of the date of the
Merger  such  that  all  options  would  be  immediately  vested  and  exercisable  by  the  holders.  In  conjunction  with  the  Merger,  the
Company agreed to assume and administer the 2006 Plan and all outstanding options to purchase shares of Viveve, Inc. common
stock issued from the 2006 Plan were converted into options to purchase shares of the Company’s common stock (rounded down to
the nearest whole share). There are currently outstanding stock option awards issued from the 2006 Plan covering a total of 38,378
shares of the Company’s common stock and no shares are available for future awards. The weighted average exercise price of the
outstanding stock options is $10.49 per share and the weighted average remaining contractual term is 4.88 years.

The 2013  Plan  was  also  adopted  by  the  Company’s  board  of  directors  and  approved  by  its  stockholders.  The  2013  Plan  is
administered by the compensation committee of the Company’s board of directors (the “Administrator”). Under the 2013 Plan, the
Company may grant equity awards to eligible participants which may take the form of stock options (both incentive stock options
and  non-qualified  stock  options),  stock  appreciation  rights,  restricted,  deferred  or  unrestricted  stock  awards,  performance-based
awards or dividend equivalent rights. Awards  may be granted to officers, employees, nonemployee directors (as defined in the 2013
Plan) and other key persons (including consultants and prospective employees). The term of any stock option award may not exceed
10  years  and may be  subject  to  vesting  conditions,  as  determined  by  the Administrator.  Options  granted  generally  vest  over  four
years.  Incentive  stock  options m a y be  granted  only  to  employees  of  the  Company  or  any  subsidiary  that  is  a  “subsidiary
corporation”  within  the  meaning  of  Section 424(f)  of  the  Internal  Revenue  Code.  The  exercise  price  of  any  stock  option  award
cannot  be  less  than  the  fair  market  value  of  the  Company’s  common  stock,  provided,  however,  that  an  incentive  stock  option
granted to an employee who owns more than 10% of the Company’s outstanding voting power must have an exercise price of no
less than 110% of the fair market value of the Company’s common stock and a term that does not exceed five years.

On August 22, 2016, the Company’s stockholders approved an amendment to the  2013 Plan to add an “evergreen” provision which
will  automatically  increase  annually,  on  the first  day  of  each January, the maximum number of shares of common stock reserved
and  available  under  the 2013  plan  (the  “Stock  Issuable”)  by  an  amount  equal  to  the  lesser  of  (i)  the  number  of  shares  that  will
increase the Stock Issuable by 4% of the total number of shares of common stock outstanding (on a fully diluted basis) or (ii) an
amount determined by the board of directors. On December 23, 2016, the board of directors approved the 2017 evergreen increasing
the total stock reserved for issuance under the 2013  Plan  by 523,209  shares  from 2,000,000  shares  to  a  total  of 2,523,209  shares,
which was effective January 1, 2017. On August 15, 2017, the Company’s stockholders approved an amendment to the  2013 Plan
increasing the number of shares of common stock authorized for awards under the 2013  Plan  from 2,523,209  shares  to  a  total  of
4,000,000 shares. On December 6, 2017, the board of directors approved the 2018 evergreen increasing the total stock reserved for
issuance under the 2013 Plan by 780,143 shares from 4,000,000 shares to a total of 4,780,143 shares, which was effective January 1,
2018.

As of December 31, 2017, there are outstanding stock option awards issued from the 2013 Plan covering a total of 2,655,846 shares
of the Company’s common stock and there remain reserved for future awards  1,186,527 shares of the Company’s common stock.
The weighted average exercise price of the outstanding stock options is $5.73 per share, and the remaining contractual term is 8.64
years.

F-21

 
 
 
 
 
 
 
Activity under the 2005 Plan, the 2006 Plan and the 2013 Plan is as follows:

    Weighted      

  Number

of

    Weighted     Average
    Average
Exercise

    Remaining    
    Contractual    

Shares

Price

    Term (years)    

    Aggregate  
Intrinsic
Value
(in
thousands)  

Options outstanding, December 31, 2015
Options granted
Options exercised
Options cancelled
Options outstanding, December 31, 2016
Options granted
Options exercised
Options cancelled
Options outstanding, December 31, 2017

1,022,195    $
978,966    $
(3,020)   $
(88,377)   $
1,909,764    $
1,000,985    $
(7,730)   $
(208,795)   $
2,694,224    $

6.47     
6.00       
4.80       
7.41       
6.19     
5.68       
4.02       
8.88       
5.80     

9.37    $

1,194,180 

9.12    $

211,396 

8.58    $

249,154 

Vested and exercisable and expected to vest, end of period

2,539,133    $

5.80     

8.55    $

239,624 

Vested and exercisable, end of period

843,008    $

5.86     

7.65    $

116,261 

The aggregate intrinsic value reflects the difference between the exercise price of the underlying stock options and the Company ’s
closing share price as of December 31, 2017.

The options outstanding and exercisable as of December 31, 2017 are as follows: 

Options Outstanding

Options Exercisable

Range of

Exercise Prices

Number

  Outstanding

as of
December 31,
2017

    Weighted
Average
Exercise

Weighted
Average
Remaining
Contractual

Price

    Term (Years)

Number
Exercisable
as of
December 31,
2017

Weighted
Average
Exercise

Price

$3.68
$4.46

$3.76
$5.01

$5.46

$5.67

$6.24
$7.00

$6.61
$7.92

$2.64  
-
-
  $5.22  
-
  $6.00  
-
-
  $9.92  
-

$56.00

$296.00   

12,500    $
66,876    $
542,829    $
557,358    $
365,000    $
557,753    $
122,038    $
431,492    $
38,135    $
243    $
2,694,224    $

2.64     
3.76     
4.72     
5.22     
5.58     
6.00     
6.44     
7.65     
9.92     
100.46     
5.80     

7.37     
7.10     
8.51     
8.94     
9.72     
7.96     
8.18     
8.75     
4.89     
2.96     
8.58     

8,334    $
47,371    $
183,555    $
146,696    $
-    $
278,880    $
36,766    $
103,028    $
38,135    $
243    $
843,008    $

2.64 
3.76 
4.75 
5.22 
- 
6.00 
6.32 
7.72 
9.92 
100.46 
5.86 

Restricted Stock Awards

In January 2016, the Company granted restricted stock awards (“RSAs”) for 39,494 shares of common stock under the 2013 Plan to
employees for 2015 accrued bonuses with a weighted average grant date fair value of $6.24 per share, based on the market price of
the Company’s common stock on the award date. A total of  89 shares pursuant to an RSA were cancelled in September  2016. The
remaining  RSAs  vested  on  the one-year anniversary of the award date in January  2017 and 39,405 shares of common stock were
issued.

In August 2016, the Company granted RSAs for 5,998 shares of common stock under the 2013 Plan to board members as director
compensation  with  a  weighted  average  grant  date  fair  value  of $7.89  per  share,  based  on  the  market  price  of  the  Company’s
common stock on the award date. The RSAs were fully vested on the date of grant and 5,998 shares of common stock were issued.

F-22

 
 
 
 
   
 
     
 
 
 
 
   
 
 
 
 
 
   
 
 
 
   
 
     
     
 
       
       
 
   
   
       
 
   
       
 
   
       
 
   
   
       
 
   
       
 
   
       
 
   
 
     
     
 
       
       
 
   
 
     
     
 
       
       
 
   
 
   
 
 
 
 
 
   
 
 
 
 
   
 
     
 
   
     
 
     
 
 
 
 
 
 
   
   
   
 
 
 
 
   
   
   
   
 
 
   
   
   
   
 
 
   
   
   
 
 
 
 
     
       
       
       
       
 
 
   
   
   
   
   
   
   
   
   
 
 
 
   
 
 
 
 
In September 2016, the Company granted 25,000 shares to a consultant with a weighted average grant date fair value of $7.58 per
share, based on the market price of the Company’s common stock on the award date. The RSA vests over  one year at a rate of 1/4th
per quarter beginning as of the award date. As of December 31, 2017, 25,000 shares were vested and issued.

In November  2016, the Company  granted  RSAs  for 6,544  shares  of  common  stock  under  the 2013  Plan  to  board  members  as
director compensation with a weighted average grant date fair value of $5.91 per share, based on the market price of the Company’s
common stock on the award date. The RSAs were fully vested on the date of grant and 6,544 shares of common stock were issued.

In May  2017, the  Company  granted  RSAs  for 4,797  shares  of  common  stock  under  the 2013  Plan  to  board  members  as  director
compensation  with  a  weighted  average  grant  date  fair  value  of $7.07  per  share,  based  on  the  market  price  of  the  Company’s
common stock on the award date. The RSAs were fully vested on the date of grant and 4,797 shares of common stock were issued.

In September  2017, the  Company  granted  RSAs  for 6,947  shares  of  common  stock  under  the 2013  Plan  to  board  members  as
director compensation with a weighted average grant date fair value of $5.58 per share, based on the market price of the Company’s
common stock on the award date. The RSAs were fully vested on the date of grant and 6,947 shares of common stock were issued.

In October 2017, the Company granted RSAs for 7,884 shares of common stock under the 2013 Plan to board members as director
compensation  with  a  weighted  average  grant  date  fair  value  of  $5.55  per  share,  based  on  the  market  price  of  the  Company’s
common stock on the award date. The RSAs were fully vested on the date of grant and 7,884 shares of common stock were issued.

In December 2017, the Company granted an RSA for 10,000 shares to an employee with a weighted average grant date fair value of
$4.94 per share, based on the market price of the Company’s common stock on the award date. The RSA vests over four years at a
rate of 1/4th the first year beginning as of the award date and monthly thereafter. As of  December 31, 2017, zero shares were vested
and issued.

There were 10,000 shares of unvested RSAs as of December 31, 2017.

2017 Employee Stock Purchase Plan

In August 2017, the stockholders approved the Company ’s 2017 Employee Stock Purchase Plan (the “2017 ESPP”). The Company
reserved a total of 400,000 shares of common stock for issuance under the 2017 ESPP. Eligible employees may purchase shares of
common  stock  through  periodic  payroll  deductions,  with  a  maximum  purchase  of 2,000  shares  of  common  stock  in  any  offering
period.  The  price  of  common  stock  purchased  under  the 2017  ESPP  is  equal  to 85%  of  the  lesser  of  the  fair  market  value  of
common stock on the first or last day of the offering period. Each offering period is for a period of  three months. The first offering
period  under  the 2017  ESPP  began  on October  1,  2017 and  ended  on December  31,  2017, and 17,894  shares  were  issued  on
December 29, 2017 at a purchase price of $4.2245. As of December 31, 2017, the remaining shares available for issuance under the
2017 ESPP were 382,106 shares.

F-23

 
 
 
 
 
 
 
 
 
 
 
The Company estimates the fair value of purchase rights under the ESPP using a Black-Scholes valuation model. The  fair value of
each  purchase  right  under  the  ESPP  was  estimated  on  the  date  of  grant  using  the  Black-Scholes  option  valuation  model  and  the
straight-line attribution approach with the following weighted-average assumptions:

Expected term (in years)
Average volatility
Risk-free interest rate
Dividend yield

  Year Ended
  December 31,

2017

0.25 

61%
1.06%
0%

The weighted average grant date fair value of the purchase rights issued under the  2017 ESPP during the year ended December 31,
2017 was $1.51 per share.

Stock-Based Compensation

During the years ended December 31, 2017  and 2016, the Company granted stock options to employees to purchase 981,110 and
919,841  shares  of  common  stock  with  a  weighted  average  grant  date  fair  value  of $2.88  and $2.63  per  share,  respectively.  The
aggregate intrinsic value of options exercised during the year ended December 31, 2017 and 2016 was $31,000 and $5,000.

The Company estimated the fair value of stock options using the Black-Scholes option pricing model. The fair value of employee
stock options is being amortized on a straight-line basis over the requisite service period of the awards. The fair value of employee
stock options granted was estimated using the following weighted average assumptions: 

Expected term (in years)
Average volatility
Risk-free interest rate
Dividend yield

Year Ended
December 31,

2017

5
59%
1.89%
0%

2016

5
49%
1.78%
0%

During the year ended December 31, 2017 and 2016, the Company granted stock options to nonemployees to purchase 19,875 and
59,125 shares of common stock with a weighted average grant date fair value of $4.09 and $4.60 per share. There were no options
exercised by nonemployees during the years ended December 31, 2017 and 2016. 

The fair value of nonemployee stock options granted was estimated using the following weighted average assumptions: 

Expected term (in years)
Average volatility
Risk-free interest rate
Dividend yield

Year Ended
December 31,

2017

10
72%
2.38%
0%

2016

10
51%
2.43%
0%

Option-pricing  models  require  the  input  of  various  subjective  assumptions,  including  the  option ’s  expected  life  and  the  price
volatility of the underlying stock. The expected stock price volatility is based on analysis of the Company’s stock price history over
a  period  commensurate  with  the  expected  term  of  the  options,  trading  volume  of  comparable  companies’  stock,  look-back
volatilities and the Company specific events that affected volatility in a prior period. The expected term of employee stock options
represents the weighted average period the stock options are expected to remain outstanding and is based on the history of exercises
and  cancellations  on  all  past  option  grants  made  by  the  Company,  the  contractual  term,  the  vesting  period  and  the  expected
remaining  term  of  the  outstanding  options.  The  risk-free  interest  rate  is  based  on  the  U.S.  Treasury  interest  rates  whose  term  is
consistent with the expected life of the stock options. No dividend yield is included as the Company has not issued any dividends
and does not anticipate issuing any dividends in the future.

F-24

 
 
 
 
 
 
 
 
 
 
 
     
 
   
   
   
   
 
  
 
 
 
 
 
 
 
 
 
 
 
   
 
 
   
     
 
 
   
 
 
   
 
 
   
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
   
     
 
 
   
 
 
   
 
 
   
 
 
   
 
 
  
The following table shows stock-based compensation expense included in the consolidated statements of operations for the years
ended December 31, 2017 and 2016 (in thousands):

Cost of revenue
Research and development
Selling, general and administrative
Total

Year Ended
December 31,

2017

2016

  $

  $

19    $
252     
1,601     
1,872    $

- 
114 
906 
1,020 

As of December 31, 2017, the total unrecognized compensation cost in connection with unvested stock options was approximately
$4,547,000. These costs are expected to be recognized over a period of approximately 2.8 years.

11. Income Taxes

No  provision  for  income  taxes  has  been  recorded  due  to  the  net  operating  losses  incurred  from  inception  to  date,  for  which no
benefit has been recorded.

A reconciliation of the U.S. statutory income tax rate to the Company’s effective tax rate is as follows:

Income tax provision (benefit) at statutory rate
State income taxes, net of federal benefit
Change in valuation allowance
Effect of tax legislation
Other
Effective tax rate

Year Ended
December 31,

2017

2016

(34)%   
(4)%   
4%    
33%    
1%    
0%    

(34)%
(2)%
33%
0%
3%
0%

The components of the Company’s net deferred tax assets and liabilities are as follows (in thousands):

December 31,

2017

2016

Deferred tax assets:

Net operating loss carryforwards
Capitalized start up costs
Research and development credits
Accruals and reserves
Fixed assets and depreciation

Total deferred tax assets
Deferred tax liabilities:

Fixed assets and depreciation

Valuation allowance

  $

19,699    $
3,963     
835     
1,403     
39     
25,939     

-     
(25,939)   

Net deferred tax assets

  $

-    $

F-25

16,888 
5,944 
518 
1,095 
- 
24,445 

(7)
(24,438)

- 

 
 
 
 
 
 
 
 
 
 
 
   
 
 
     
       
 
   
   
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
     
 
     
 
   
   
   
   
   
   
 
 
 
 
 
 
 
   
 
     
       
 
   
   
   
   
   
     
       
 
   
   
 
     
       
 
 
The  Company  has  recorded  a  full  valuation  allowance  for  its  deferred  tax  assets  based  on  it  past  losses  and  the  uncertainty
regarding  the  ability  to project  future  taxable  income.  The  valuation  allowance  increased  by  approximately $1,501,000  and
$5,750,000 during the years ended December 31, 2017 and 2016, respectively.

As of December 31, 2017, the Company has net operating loss (“NOL”) carryforwards for federal and state income tax purposes of
approximately $78,858,000 and $50,517,000, respectively, which expire beginning in the year 2026.

The  Company  also  has  federal  and  California  research  and  development  tax  credits  of  approximately $701,000  and $623,000,
respectively. The federal research credits will begin to expire in 2026 and the California research and development credits have no
expiration date.

Utilization of the NOL and research and development credit carryforwards may be subject to a substantial annual limitation due to
ownership  changes  that  have  occurred  previously  or  that  could  occur  in  the  future,  as  provided  by  Section 382  of  the  Internal
Revenue  Code  of 1986,  as  well  as  similar  state  provisions.  Ownership  changes may limit  the  amount  of  NOL  and  tax  credit
carryforwards that can be utilized to offset future taxable income and tax, respectively. In general, an ownership change, as defined
by  Section 382,  results  from  transactions  increasing  the  ownership  of  certain  shareholders  or  public  groups  in  the  stock  of  a
corporation  by  more  than 50  percentage  points  over  a three-year  period.  If  the  Company  has  experienced  a  change  of  control,
utilization of its NOL or tax credits carryforwards would be subject to an annual limitation under Section 382. Any limitation  may
result  in  expiration  of  a  portion  of  the  NOL  or  research  and  development  credit  carryforwards  before  utilization.  Subsequent
ownership  changes  could  further  impact  the  limitation  in  future  years.  Until  a  Section 382 study is completed and any limitation
known, no  amounts  are  being  presented  as  an  uncertain  tax  position. A  full  valuation  allowance  has  been  provided  against  the
Company’s  NOL  carryforwards  and  research  and  development  credit  carryforwards  and,  if  an  adjustment  is  required,  this
adjustment  would  be  offset  by  an  adjustment  to  the  valuation  allowance.  Thus,  there  would  be no  net  impact  to  the  consolidated
balance sheets or the consolidated statements of operations if an adjustment were required.

As of December 31, 2017, the Company had not accrued any interest or penalties related to uncertain tax positions.

A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows (in thousands):

Year Ended
December 31,

2017

2016

Balance at the beginning of the year
Additions based upon tax positions related to the current year
Balance at the end of the year

  $

  $

268    $
129     
397    $

128 
140 
268 

If the ending balance of  $397,000 of unrecognized tax benefits as of December 31, 2017 were recognized, none of the recognition
would affect the income tax rate. The Company does not anticipate any material change in its unrecognized tax benefits over the
next twelve months. The unrecognized tax benefits may change during the next year for items that arise in the ordinary course of
business.

The  Company  files  U.S.  federal  and  state  income  tax  returns  with  varying  statutes  of  limitations. All  tax  years  since  inception
remain open to examination due to the carryover of unused net operating losses and tax credits.

On December 22, 2017, the United States enacted a law commonly known as the Tax Cuts and Jobs Act (“ TCJA”) which makes
widespread changes to the Internal Revenue Code, including a reduction in the federal corporate tax rate to 21%, and repatriation of
accumulated foreign accumulated earnings and profits, effective January 1, 2018.

The Company is required to recognize the effect on deferred tax assets and liabilities of a change in tax rates be recognized in the
period the tax rate change was enacted. The carrying value of our U.S. deferred taxes is determined by the enacted U.S. corporate
income tax rate. Consequently, the reduction in the U.S. corporate income tax rate impacts the carrying value of our deferred tax
assets. Under the new corporate income tax rate of 21%, the U.S. net deferred tax asset position will decrease as will the related
valuation allowance. The Company has also considered the impact of the transition tax for which it has estimated it does  not need
to accrue a liability as the operations of Viveve BV are immaterial. Uncertainty regarding the impact of tax reform remains, as a
result  of  factors  including  future  regulatory  and  rulemaking  processes,  the  prospects  of  additional  corrective  or  supplemental
legislation,  potential  trade  or  other  litigation,  and  other  factors.  As  such,  while  the  Company  believes  that  these  adjustments
are reasonable estimates of TCJA, they should be considered provisional.

12. Related Party Transactions

I n June  2006,  the  Company  entered  into  a  Development  and  Manufacturing  Agreement  (the  “Agreement”)  with  Stellartech
Research  Corporation  (“Stellartech”).  The  Agreement  was  amended  on October 4,  2007.  Under  the  Agreement,  the  Company
agreed to purchase 300 generators manufactured by Stellartech. As of December 31, 2017, the Company has purchased 543 units.
The  price  per  unit  is  variable  and  dependent  on  the  volume  and  timing  of  units  ordered.  In  conjunction  with  the Agreement,
Stellartech  purchased 37,500  shares  of  Viveve,  Inc.’s  common  stock.  Under  the  Agreement,  the  Company  paid  Stellartech
$7,912,000 and $6,485,000 for goods and services during the years ended December 31, 2017 and 2016, respectively.

F-26

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
     
       
 
   
 
 
 
 
 
 
 
  
13. Segments and Geographic Information

The Company has determined that it operates as a single operating and reportable segment. Revenue from unaffiliated customers by
geographic area was as follows (in thousands):

United States
Asia Pacific
Europe and Middle East
Latin America
Canada
Total

Year Ended
December 31,

2017

2016

  $

  $

11,004     
3,178     
667     
360     
79     
15,288    $

315 
4,946 
1,489 
382 
9 
7,141 

The Company determines geographic location of its revenue based upon the destination of shipments of its products.

The Company’s long-lived assets by geographic area were as follows (in thousands):

United States
Asia Pacific
Canada
Latin America
Europe
Total

Year Ended
December 31,

2017

2016

  $

  $

1,192    $
52     
46     
12     
1     
1,303    $

370 
39 
2 
- 
72 
483 

Long-lived assets, comprised of property and equipment, are reported based on the location of the assets at ea ch balance sheet date.

14. Subsequent Events

On February 12, 2018, in connection with the closing of a public offering (the “ February 2018 Offering”), the Company issued an
aggregate of 11,500,000 shares of common stock, including the shares issued in connection with the exercise of the underwriters’
overallotment  option,  at  a  public  offering  price  of $3.00  per  share  for  gross  proceeds  of  approximately $34,500,000.  The  net
proceeds  to  the  Company  were  approximately $32,380,000,  after  deducting  underwriting  discounts  and  commissions  (but  before
deducting estimated offering expenses payable by the Company). 

In January 2018,  the  Company  sold 208,277  shares  of  common  stock  for  net  proceeds  of  approximately $1,025,000  under  the
November 2017 ATM Facility. There have been  no other shares sold under the November 2017 ATM Facility through the date of
this filing.

F-27

 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
     
       
 
   
   
   
   
 
 
 
 
 
 
 
 
 
 
 
   
 
 
     
       
 
   
   
   
   
 
 
 
 
 
 
INDEMNIFICATION AGREEMENT

Exhibit 10.52

This Indemnification Agreement (“Agreement”) is made as of ________________ by and between Viveve Medical Inc., a

Delaware corporation (the “Company”), and ____________ (“Indemnitee”).

RECITALS

WHEREAS, the Company desires to attract and retain the services of highly qualified individuals, such as Indemnitee, to serve

the Company;

WHEREAS, in order to induce Indemnitee to continue to provide services to the Company, the Company wishes to provide for

the indemnification of, and advancement of expenses to, Indemnitee to the maximum extent permitted by law;

WHEREAS, the Bylaws (the “Bylaws”) of the Company require indemnification of the officers and directors of the Company,

and Indemnitee may also be entitled to indemnification pursuant to the General Corporation Law of the State of Delaware (the “DGCL”);

WHEREAS, the Bylaws and the DGCL expressly provide that the indemnification provisions set forth therein are not exclusive,

and thereby contemplate that contracts may be entered into between the Company and members of the board of directors, officers and
other persons with respect to indemnification;

WHEREAS, the Board of Directors of the Company (the “ Board”) has determined that the increased difficulty in attracting and

retaining highly qualified persons such as Indemnitee is detrimental to the best interests of the Company’s stockholders;

WHEREAS, it is reasonable and prudent for the Company contractually to obligate itself to indemnify, and to advance expenses
on behalf of, such persons to the fullest extent permitted by applicable law, regardless of any amendment or revocation of the Bylaws, so
that they will continue to serve the Company free from undue concern that they will not be so indemnified;

WHEREAS, this Agreement is a supplement to and in furtherance of the indemnification provided in the Bylaws and any
resolutions adopted pursuant thereto, and shall not be deemed a substitute therefor, nor to diminish or abrogate any rights of Indemnitee
thereunder; and

NOW, THEREFORE, in consideration of the premises and the covenants contained herein, the Company and Indemnitee do

hereby covenant and agree as follows:

Section 1.      Services to the Company. Indemnitee agrees to serve as a director of the Company. Indemnitee may at any time and
for any reason resign from such position (subject to any other contractual obligation or any obligation imposed by law), in which event the
Company shall have no obligation under this Agreement to continue Indemnitee in such position. This Agreement shall not be deemed an
employment contract between the Company (or any of its subsidiaries or any Enterprise) and Indemnitee.

1

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Section 2.      Definitions.

As used in this Agreement:

(a)    “Change in Control” shall mean:

(i)      the date any “person,” as such term is used in Sections 13(d) and 14(d) of the Securities Exchange Act of
1934, as amended (the “Act”) (other than the Company, any of its subsidiaries, or any trustee, fiduciary or other person or
entity holding securities under any employee benefit plan or trust of the Company or any of its subsidiaries), together with
all  “affiliates”  and  “associates”  (as  such  terms  are  defined  in  Rule  12b-2  under  the Act)  of  such  person,  becomes  the
“beneficial  owner”  (as  such  term  is  defined  in  Rule  13d-3  under  the Act),  directly  or  indirectly,  of  securities  of  the
Company  representing  fifty  percent  (50%)  or  more  of  the  combined  voting  power  of  the  Company’s  then  outstanding
securities having the right to vote in an election of the Board (“Voting Securities”) (in such case other than as a result of
an acquisition of securities directly from the Company); or

(ii)          the  date  a  majority  of  the  members  of  the  Board  is  replaced  during  any  12-month  period  by  directors
whose  appointment  or  election  is  not  endorsed  by  a  majority  of  the  members  of  the  Board  before  the  date  of  the
appointment or election; or

(iii)     the date of consummation of (A) any consolidation or merger of the Company where the stockholders of the
Company, immediately prior to the consolidation or merger, would not, immediately after the consolidation or merger, beneficially
own (as such term is defined in Rule 13d-3 under the Act), directly or indirectly, shares representing in the aggregate more than
fifty percent (50%) of the voting shares of the resulting or successor entity in the consolidation or merger (or of its ultimate parent
entity, if any), or (B) any sale or other transfer (in one transaction or a series of transactions contemplated or arranged by any party
as a single plan) of all or substantially all of the assets of the Company on a consolidated basis to a person or entity not affiliated
with the Company.

(b)     “Corporate Status” describes the status of a person as a current or former director of the Company or current or
former director, manager, partner, officer, employee, agent or trustee of any other Enterprise which such person is or was serving at the
request of the Company.

(c)     “Enforcement Expenses” shall include all reasonable attorneys’ fees, court costs, transcript costs, fees of experts,

travel expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees, and all other out-of-pocket
disbursements or expenses of the types customarily incurred in connection with an action to enforce indemnification or advancement
rights, or an appeal from such action. Expenses, however, shall not include fees, salaries, wages or benefits owed to Indemnitee.

2

 
 
 
 
 
 
 
 
 
 
(d)     “Enterprise” shall mean any corporation (other than the Company), partnership, joint venture, trust, employee
benefit plan, limited liability company, or other legal entity of which Indemnitee is or was serving at the request of the Company as a
director, manager, partner, officer, employee, agent or trustee.

(e)     “Expenses” shall include all reasonable attorneys’ fees, court costs, transcript costs, fees of experts, travel

expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees, and all other out-of-pocket
disbursements or expenses of the types customarily incurred in connection with prosecuting, defending, preparing to prosecute or defend,
investigating, being or preparing to be a witness in, or otherwise participating in, a Proceeding or an appeal resulting from a Proceeding.
Expenses, however, shall not include amounts paid in settlement by Indemnitee, the amount of judgments or fines against Indemnitee or
fees, salaries, wages or benefits owed to Indemnitee.

(f)     “Independent Counsel” means a law firm, or a partner (or, if applicable, member or shareholder) of such a law firm,

that is experienced in matters of Delaware corporation law and neither presently is, nor in the past five (5) years has been, retained to
represent: (i) the Company, any subsidiary of the Company, any Enterprise or Indemnitee in any matter material to any such party; or (ii)
any other party to the Proceeding giving rise to a claim for indemnification hereunder. Notwithstanding the foregoing, the term
“Independent Counsel” shall not include any person who, under the applicable standards of professional conduct then prevailing, would
have a conflict of interest in representing either the Company or Indemnitee in an action to determine Indemnitee’s rights under this
Agreement. The Company agrees to pay the reasonable fees and expenses of the Independent Counsel referred to above and to fully
indemnify such counsel against any and all expenses, claims, liabilities and damages arising out of or relating to this Agreement or its
engagement pursuant hereto.

(g)     The term “Proceeding” shall include any threatened, pending or completed action, suit, arbitration, alternate

dispute resolution mechanism, investigation, inquiry, administrative hearing or any other actual, threatened or completed proceeding,
whether brought in the right of the Company or otherwise and whether of a civil, criminal, administrative, regulatory or investigative
nature, and whether formal or informal, in which Indemnitee was, is or will be involved as a party or otherwise by reason of the fact that
Indemnitee is or was a director of the Company or is or was serving at the request of the Company as a director, manager, partner, officer,
employee, agent or trustee of any Enterprise or by reason of any action taken by Indemnitee or of any action taken on his or her part while
acting as a director of the Company or while serving at the request of the Company as a director, manager, partner, officer, employee,
agent or trustee of any Enterprise, in each case whether or not serving in such capacity at the time any liability or expense is incurred for
which indemnification, reimbursement or advancement of expenses can be provided under this Agreement; provided, however, that the
term “Proceeding” shall not include any action, suit or arbitration, or part thereof, initiated by Indemnitee to enforce Indemnitee’s rights
under this Agreement as provided for in Section 12(a) of this Agreement.

3

 
 
 
 
 
 
Section 3.     Indemnity in Third-Party Proceedings. The Company shall indemnify Indemnitee to the extent set forth in this

Section 3 if Indemnitee is, or is threatened to be made, a party to or a participant in any Proceeding, other than a Proceeding by or in the
right of the Company to procure a judgment in its favor. Pursuant to this Section 3, Indemnitee shall be indemnified against all Expenses,
judgments, fines, penalties, excise taxes, and amounts paid in settlement actually and reasonably incurred by Indemnitee or on his or her
behalf in connection with such Proceeding or any claim, issue or matter therein, if Indemnitee acted in good faith and in a manner he or she
reasonably believed to be in or not opposed to the best interests of the Company and, in the case of a criminal proceeding, had no
reasonable cause to believe that his or her conduct was unlawful.

Section 4.     Indemnity in Proceedings by or in the Right of the Company. The Company shall indemnify Indemnitee to the

extent set forth in this Section 4 if Indemnitee is, or is threatened to be made, a party to or a participant in any Proceeding by or in the right
of the Company to procure a judgment in its favor. Pursuant to this Section 4, Indemnitee shall be indemnified against all Expenses
actually and reasonably incurred by Indemnitee or on his or her behalf in connection with such Proceeding or any claim, issue or matter
therein, if Indemnitee acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the
Company. No indemnification for Expenses shall be made under this Section 4 in respect of any claim, issue or matter as to which
Indemnitee shall have been finally adjudged by a court to be liable to the Company, unless and only to the extent that the Delaware Court
of Chancery (the “Delaware Court”) shall determine upon application that, despite the adjudication of liability but in view of all the
circumstances of the case, Indemnitee is fairly and reasonably entitled to indemnification for such expenses as the Delaware Court shall
deem proper.

Section 5.     Indemnification for Expenses of a Party Who is Wholly or Partly Successful. Notwithstanding any other provisions
of this Agreement and except as provided in Section 7, to the extent that Indemnitee is a party to or a participant in any Proceeding and is
successful in such Proceeding or in defense of any claim, issue or matter therein, the Company shall indemnify Indemnitee against all
Expenses actually and reasonably incurred by him or her in connection therewith. If Indemnitee is not wholly successful in such
Proceeding but is successful as to one or more but less than all claims, issues or matters in such Proceeding, the Company shall indemnify
Indemnitee against all Expenses actually and reasonably incurred by Indemnitee or on his or her behalf in connection with each
successfully resolved claim, issue or matter. For purposes of this Section and without limitation, the termination of any claim, issue or
matter in such a Proceeding by dismissal, with or without prejudice, shall be deemed to be a successful result as to such claim, issue or
matter.

Section 6.     Reimbursement for Expenses of a Witness or in Response to a Subpoena. Notwithstanding any other provision of

this Agreement, to the extent that Indemnitee, by reason of his or her Corporate Status, (i) is a witness in any Proceeding to which
Indemnitee is not a party and is not threatened to be made a party or (ii) receives a subpoena with respect to any Proceeding to which
Indemnitee is not a party and is not threatened to be made a party, the Company shall reimburse Indemnitee for all Expenses actually and
reasonably incurred by him or her or on his or her behalf in connection therewith.

4

 
 
 
 
 
 
Section 7.     Exclusions. Notwithstanding any provision in this Agreement to the contrary, the Company shall not be obligated

under this Agreement:

(a)     to indemnify for amounts otherwise indemnifiable hereunder (or for which advancement is provided hereunder) if

and to the extent that Indemnitee has otherwise actually received such amounts under any insurance policy, contract, agreement or
otherwise;

(b)     to indemnify for an accounting of profits made from the purchase and sale (or sale and purchase) by Indemnitee of
securities of the Company within the meaning of Section 16(b) of the Securities Exchange Act of 1934, as amended, or similar provisions
of state statutory law or common law;

(c)     to indemnify with respect to any Proceeding, or part thereof, brought by Indemnitee against the Company, any

legal entity which it controls, any director or officer thereof or any third party, unless (i) the Board has consented to the initiation of such
Proceeding or part thereof and (ii) the Company provides the indemnification, in its sole discretion, pursuant to the powers vested in the
Company under applicable law; provided, however, that this Section 7(d) shall not apply to (A) counterclaims or affirmative defenses
asserted by Indemnitee in an action brought against Indemnitee or (B) any action brought by Indemnitee for indemnification or
advancement from the Company under this Agreement or under any directors’ and officers’ liability insurance policies maintained by the
Company in the suit for which indemnification or advancement is being sought as described in Section 12; or

at the time payment would otherwise be required pursuant to this Agreement).

(e)     to provide any indemnification or advancement of expenses that is prohibited by applicable law (as such law exists

Section 8.     Advancement of Expenses. Subject to Section 9(b), the Company shall advance, to the extent not prohibited by law,
the Expenses incurred by Indemnitee in connection with any Proceeding, and such advancement shall be made within thirty (30) days after
the receipt by the Company of a statement or statements requesting such advances (including any invoices received by Indemnitee, which
such invoices may be redacted as necessary to avoid the waiver of any privilege accorded by applicable law) from time to time, whether
prior to or after final disposition of any Proceeding. Advances shall be unsecured and interest free. Advances shall be made without regard
to Indemnitee’s (i) ability to repay the expenses, (ii) ultimate entitlement to indemnification under the other provisions of this Agreement,
and (iii) entitlement to and availability of insurance coverage, including advancement, payment or reimbursement of defense costs,
expenses or covered loss under the provisions of any applicable insurance policy (including, without limitation, whether such
advancement, payment or reimbursement is withheld, conditioned or delayed by the insurer(s)). Indemnitee shall qualify for advances
upon the execution and delivery to the Company of this Agreement which shall constitute an undertaking providing that Indemnitee
undertakes to the fullest extent required by law to repay the advance if and to the extent that it is ultimately determined by a court of
competent jurisdiction in a final judgment, not subject to appeal, that Indemnitee is not entitled to be indemnified by the Company. The
right to advances under this paragraph shall in all events continue until final disposition of any Proceeding, including any appeal therein.
Nothing in this Section 8 shall limit Indemnitee’s right to advancement pursuant to Section 12(e) of this Agreement.

5

 
 
 
 
 
 
 
 
Section 9.     Procedure for Notification and Defense of Claim.

(a)     To obtain indemnification under this Agreement, Indemnitee shall submit to the Company a written request

therefor specifying the basis for the claim, the amounts for which Indemnitee is seeking payment under this Agreement, and all
documentation related thereto as reasonably requested by the Company.

(b)     In the event that the Company shall be obligated hereunder to provide indemnification for or make any

advancement of Expenses with respect to any Proceeding, the Company shall be entitled to assume the defense of such Proceeding, or any
claim, issue or matter therein, with counsel approved by Indemnitee (which approval shall not be unreasonably withheld or delayed) upon
the delivery to Indemnitee of written notice of the Company’s election to do so. After delivery of such notice, approval of such counsel by
Indemnitee and the retention of such counsel by the Company, the Company will not be liable to Indemnitee under this Agreement for any
fees or expenses of separate counsel subsequently employed by or on behalf of Indemnitee with respect to the same Proceeding; provided
that (i) Indemnitee shall have the right to employ separate counsel in any such Proceeding at Indemnitee’s expense and (ii) if (A) the
employment of separate counsel by Indemnitee has been previously authorized by the Company, (B) Indemnitee shall have reasonably
concluded that there may be a conflict of interest between the Company and Indemnitee in the conduct of such defense, or (C) the
Company shall not continue to retain such counsel to defend such Proceeding, then the fees and expenses actually and reasonably incurred
by Indemnitee with respect to his or her separate counsel shall be Expenses hereunder.

the Company will be entitled to participate in the Proceeding at its own expense.

(c)      In the event that the Company does not assume the defense in a Proceeding pursuant to paragraph (b) above, then

(d)      The Company shall not be liable to indemnify Indemnitee under this Agreement for any amounts paid in

settlement of any Proceeding effected without its prior written consent (which consent shall not be unreasonably withheld or delayed).
Without limiting the generality of the foregoing, the fact that an insurer under an applicable insurance policy delays or is unwilling to
consent to such settlement or is or may be in breach of its obligations under such policy, or the fact that directors’ and officers’ liability
insurance is otherwise unavailable or not maintained by the Company, may not be taken into account by the Company in determining
whether to provide its consent. The Company shall not, without the prior written consent of Indemnitee (which consent shall not be
unreasonably withheld or delayed), enter into any settlement which (i) includes an admission of fault of Indemnitee, any non-monetary
remedy imposed on Indemnitee or any monetary damages for which Indemnitee is not wholly and actually indemnified hereunder or (ii)
with respect to any Proceeding with respect to which Indemnitee may be or is made a party or may be otherwise entitled to seek
indemnification hereunder, does not include the full release of Indemnitee from all liability in respect of such Proceeding.

6

 
 
 
 
 
 
 
Section 10.     Procedure Upon Application for Indemnification .

(a)     Upon written request by Indemnitee for indemnification pursuant to Section 9(a), a determination, if such

determination is required by applicable law, with respect to Indemnitee’s entitlement to indemnification hereunder shall be made in the
specific case by one of the following methods: (x) if a Change in Control shall have occurred, by Independent Counsel in a written opinion
to the Board; or (y) if a Change in Control shall not have occurred: (i) by a majority vote of the disinterested directors, even though less
than a quorum; (ii) by a committee of disinterested directors designated by a majority vote of the disinterested directors, even though less
than a quorum; or (iii) if there are no disinterested directors or if the disinterested directors so direct, by Independent Counsel in a written
opinion to the Board. For purposes hereof, disinterested directors are those members of the Board who are not parties to the action, suit or
proceeding in respect of which indemnification is sought. In the case that such determination is made by Independent Counsel, a copy of
Independent Counsel’s written opinion shall be delivered to Indemnitee and, if it is so determined that Indemnitee is entitled to
indemnification, payment to Indemnitee shall be made within thirty (30) days after such determination. Indemnitee shall cooperate with
the Independent Counsel or the Company, as applicable, in making such determination with respect to Indemnitee’s entitlement to
indemnification, including providing to such counsel or the Company, upon reasonable advance request, any documentation or
information which is not privileged or otherwise protected from disclosure and which is reasonably available to Indemnitee and reasonably
necessary to such determination. Any out-of-pocket costs or expenses (including reasonable attorneys’ fees and disbursements) actually
and reasonably incurred by Indemnitee in so cooperating with the Independent Counsel or the Company shall be borne by the Company
(irrespective of the determination as to Indemnitee’s entitlement to indemnification) and the Company hereby indemnifies and agrees to
hold Indemnitee harmless therefrom.

(b)     If the determination of entitlement to indemnification is to be made by Independent Counsel pursuant to Section
10(a), the Independent Counsel shall be selected by the Board if a Change in Control shall not have occurred or, if a Change in Control
shall have occurred, by Indemnitee. Indemnitee or the Company, as the case may be, may, within ten (10) days after written notice of such
selection, deliver to the Company or Indemnitee, as the case may be, a written objection to such selection; provided, however, that such
objection may be asserted only on the ground that the Independent Counsel so selected does not meet the requirements of “Independent
Counsel” as defined in Section 2 of this Agreement, and the objection shall set forth with particularity the factual basis of such assertion.
Absent a proper and timely objection, the person so selected shall act as Independent Counsel. If such written objection is so made and
substantiated, the Independent Counsel so selected may not serve as Independent Counsel unless and until such objection is withdrawn or
the Delaware Court has determined that such objection is without merit. If, within twenty (20) days after the later of (i) submission by
Indemnitee of a written request for indemnification pursuant to Section 9(a), and (ii) the final disposition of the Proceeding, including any
appeal therein, no Independent Counsel shall have been selected without objection, either Indemnitee or the Company may petition the
Delaware Court for resolution of any objection which shall have been made by Indemnitee or the Company to the selection of Independent
Counsel and/or for the appointment as Independent Counsel of a person selected by the court or by such other person as the court shall
designate. The person with respect to whom all objections are so resolved or the person so appointed shall act as Independent Counsel
under Section 10(a) hereof. Upon the due commencement of any judicial proceeding or arbitration pursuant to Section 12(a) of this
Agreement, Independent Counsel shall be discharged and relieved of any further responsibility in such capacity (subject to the applicable
standards of professional conduct then prevailing).

7

 
 
 
 
 
(c)     Notwithstanding anything to the contrary contained in this Agreement, the determination of entitlement to

indemnification under this Agreement shall be made without regard to the Indemnitee’s entitlement to and availability of insurance
coverage, including advancement, payment or reimbursement of defense costs, expenses or covered loss under the provisions of any
applicable insurance policy (including, without limitation, whether such advancement, payment or reimbursement is withheld, conditioned
or delayed by the insurer(s)).

Section 11.     Presumptions and Effect of Certain Proceedings.

(a)     To the extent permitted by applicable law, in making a determination with respect to entitlement to indemnification

hereunder, it shall be presumed that Indemnitee is entitled to indemnification under this Agreement if Indemnitee has submitted a request
for indemnification in accordance with Section 9(a) of this Agreement, and the Company shall have the burden of proof to overcome that
presumption in connection with the making of any determination contrary to that presumption.

(b)     The termination of any Proceeding or of any claim, issue or matter therein, by judgment, order, settlement or

conviction, or upon a plea of guilty, nolo contendere or its equivalent, shall not (except as otherwise expressly provided in this Agreement)
of itself adversely affect the right of Indemnitee to indemnification or create a presumption that Indemnitee did not act in good faith and in
a manner which he or she reasonably believed to be in or not opposed to the best interests of the Company or, with respect to any criminal
Proceeding, that Indemnitee had reasonable cause to believe that his or her conduct was unlawful.

(c)     The knowledge and/or actions, or failure to act, of any director, manager, partner, officer, employee, agent or

trustee of the Company, any subsidiary of the Company, or any Enterprise shall not be imputed to Indemnitee for purposes of determining
the right to indemnification under this Agreement.

Section 12.     Remedies of Indemnitee.

(a)     Subject to Section 12(f), in the event that (i) a determination is made pursuant to Section 10 of this Agreement that
Indemnitee is not entitled to indemnification under this Agreement, (ii) advancement of Expenses is not timely made pursuant to Section 8
of this Agreement, (iii) no determination of entitlement to indemnification shall have been made pursuant to Section 10(a) of this
Agreement within sixty (60) days after receipt by the Company of the request for indemnification for which a determination is to be made
other than by Independent Counsel, (iv) payment of indemnification or reimbursement of expenses is not made pursuant to Section 5 or 6
or the last sentence of Section 10(a) of this Agreement within thirty (30) days after receipt by the Company of a written request therefor
(including any invoices received by Indemnitee, which such invoices may be redacted as necessary to avoid the waiver of any privilege
accorded by applicable law) or (v) payment of indemnification pursuant to Section 3 or 4 of this Agreement is not made within thirty (30)
days after a determination has been made that Indemnitee is entitled to indemnification, Indemnitee shall be entitled to an adjudication by
the Delaware Court of his or her entitlement to such indemnification or advancement. Alternatively, Indemnitee, at his or her option, may
seek an award in arbitration to be conducted by a single arbitrator pursuant to the Commercial Arbitration Rules of the American
Arbitration Association. Indemnitee shall commence such proceeding seeking an adjudication or an award in arbitration within 180 days
following the date on which Indemnitee first has the right to commence such proceeding pursuant to this Section 12(a); provided, however,
that the foregoing time limitation shall not apply in respect of a proceeding brought by Indemnitee to enforce his or her rights under
Section 5 of this Agreement. The Company shall not oppose Indemnitee’s right to seek any such adjudication or award in arbitration.

8

 
 
 
 
 
 
 
 
 
(b)     In the event that a determination shall have been made pursuant to Section 10(a) of this Agreement that Indemnitee

is not entitled to indemnification, any judicial proceeding or arbitration commenced pursuant to this Section 12 shall be conducted in all
respects as a de novo trial, or arbitration, on the merits and Indemnitee shall not be prejudiced by reason of that adverse determination. In
any judicial proceeding or arbitration commenced pursuant to this Section 12, the Company shall have the burden of proving Indemnitee is
not entitled to indemnification or advancement, as the case may be.

(c)      If a determination shall have been made pursuant to Section 10(a) of this Agreement that Indemnitee is entitled to
indemnification, the Company shall be bound by such determination in any judicial proceeding or arbitration commenced pursuant to this
Section 12, absent (i) a misstatement by Indemnitee of a material fact, or an omission of a material fact necessary to make Indemnitee’s
statement not materially misleading, in connection with the request for indemnification, or (ii) a prohibition of such indemnification under
applicable law.

(d)     The Company shall be precluded from asserting in any judicial proceeding or arbitration commenced pursuant to

this Section 12 that the procedures and presumptions of this Agreement are not valid, binding and enforceable and shall stipulate in any
such court or before any such arbitrator that the Company is bound by all the provisions of this Agreement.

(e)     The Company shall indemnify Indemnitee to the fullest extent permitted by law against any and all Enforcement

Expenses and, if requested by Indemnitee, shall (within thirty (30) days after receipt by the Company of a written request therefor)
advance, to the extent not prohibited by law, such Enforcement Expenses to Indemnitee, which are incurred by Indemnitee in connection
with any action brought by Indemnitee for indemnification or advancement from the Company under this Agreement or under any
directors’ and officers’ liability insurance policies maintained by the Company in the suit for which indemnification or advancement is
being sought. Such written request for advancement shall include invoices received by Indemnitee in connection with such Enforcement
Expenses but, in the case of invoices in connection with legal services, any references to legal work performed or to expenditures made
that would cause Indemnitee to waive any privilege accorded by applicable law need not be included with the invoice.

9

 
 
 
 
 
 
under this Agreement shall be required to be made prior to the final disposition of the Proceeding, including any appeal therein.

(f)     Notwithstanding anything in this Agreement to the contrary, no determination as to entitlement to indemnification

Section 13.     Non-exclusivity; Survival of Rights; Insurance; Subrogation .

(a)     The rights of indemnification and to receive advancement as provided by this Agreement shall not be deemed

exclusive of any other rights to which Indemnitee may at any time be entitled under applicable law, the Certificate of Incorporation of the
Company (the “Charter”), the Bylaws, any agreement, a vote of stockholders or a resolution of directors, or otherwise. No amendment,
alteration or repeal of this Agreement or of any provision hereof shall limit or restrict any right of Indemnitee under this Agreement in
respect of any action taken or omitted by such Indemnitee in his or her Corporate Status prior to such amendment, alteration or repeal. To
the extent that a change in Delaware law, whether by statute or judicial decision, permits greater indemnification or advancement than
would be afforded currently under the Bylaws and this Agreement, it is the intent of the parties hereto that Indemnitee shall enjoy by this
Agreement the greater benefits so afforded by such change. No right or remedy herein conferred is intended to be exclusive of any other
right or remedy, and every other right and remedy shall be cumulative and in addition to every other right and remedy given hereunder or
now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise,
shall not prevent the concurrent assertion or employment of any other right or remedy.

(b)     To the extent that the Company maintains an insurance policy or policies providing liability insurance for

directors, managers, partners, officers, employees, agents or trustees of the Company or of any other Enterprise, Indemnitee shall be
covered by such policy or policies in accordance with its or their terms to the maximum extent of the coverage available for any such
director, manager, partner, officer, employee, agent or trustee under such policy or policies. If, at the time of the receipt of a notice of a
claim pursuant to the terms hereof, the Company has director and officer liability insurance in effect, the Company shall give prompt
notice of the commencement of such proceeding to the insurers in accordance with the procedures set forth in the respective policies.

(c)     In the event of any payment under this Agreement, the Company shall be subrogated to the extent of such payment
to all of the rights of recovery of Indemnitee, who shall execute all papers required and take all action necessary to  secure  such  rights,
including execution of such documents as are necessary to enable the Company to bring suit to enforce such rights.

(e)     The Company’s obligation to provide indemnification or advancement hereunder to Indemnitee who is or was

serving at the request of the Company as a director, manager, partner, officer, employee, agent or trustee of any other Enterprise shall be
reduced by any amount Indemnitee has actually received as indemnification or advancement from such other Enterprise.

10

 
 
 
 
 
 
 
 
Section 14.      Duration of Agreement. This Agreement shall continue until and terminate upon the later of: (a) ten (10) years after

the date that Indemnitee shall have ceased to serve as a director of the Company or (b) one (1) year after the final termination of any
Proceeding, including any appeal, then pending in respect of which Indemnitee is granted rights of indemnification or advancement
hereunder and of any proceeding commenced by Indemnitee pursuant to Section 12 of this Agreement relating thereto. This Agreement
shall be binding upon the Company and its successors and assigns and shall inure to the benefit of Indemnitee and his or her heirs,
executors and administrators. The Company shall require and cause any successor (whether direct or indirect by purchase, merger,
consolidation or otherwise) to all, substantially all or a substantial part, of the business and/or assets of the Company, by written
agreement in form and substance satisfactory to Indemnitee, expressly to assume and agree to perform this Agreement in the same manner
and to the same extent that the Company would be required to perform if no such succession had taken place.

Section 15.     Severability. If any provision or provisions of this Agreement shall be held to be invalid, illegal or unenforceable
for any reason whatsoever: (a) the validity, legality and enforceability of the remaining provisions of this Agreement (including, without
limitation, each portion of any section of this Agreement containing any such provision held to be invalid, illegal or unenforceable, that is
not itself invalid, illegal or unenforceable) shall not in any way be affected or impaired thereby and shall remain enforceable to the fullest
extent permitted by law; (b) such provision or provisions shall be deemed reformed to the extent necessary to conform to applicable law
and to give the maximum effect to the intent of the parties hereto; and (c) to the fullest extent possible, the provisions of this Agreement
(including, without limitation, each portion of any section of this Agreement containing any such provision held to be invalid, illegal or
unenforceable, that is not itself invalid, illegal or unenforceable) shall be construed so as to give effect to the intent manifested thereby.

Section 16.     Enforcement.

(a)     The Company expressly confirms and agrees that it has entered into this Agreement and assumed the obligations

imposed on it hereby in order to induce Indemnitee to continue to serve as a director of the Company, and the Company acknowledges that
Indemnitee is relying upon this Agreement in serving as a director of the Company.

(b)     This Agreement constitutes the entire agreement between the parties hereto with respect to the subject matter

hereof and supersedes all prior agreements and understandings, oral, written and implied, between the parties hereto with respect to the
subject matter hereof; provided, however, that this Agreement is a supplement to and in furtherance of the Charter, the Bylaws and
applicable law, and shall not be deemed a substitute therefor, nor to diminish or abrogate any rights of Indemnitee thereunder.

Section 17.     Modification and Waiver. No supplement, modification or amendment, or waiver of any provision, of this
Agreement shall be binding unless executed in writing by the parties thereto. No waiver of any of the provisions of this Agreement shall
be deemed or shall constitute a waiver of any other provisions of this Agreement nor shall any waiver constitute a continuing waiver. No
supplement, modification or amendment of this Agreement or of any provision hereof shall limit or restrict any right of Indemnitee under
this Agreement in respect of any action taken or omitted by such Indemnitee prior to such supplement, modification or amendment.

11

 
 
 
 
 
 
 
 
Section 18.     Notice by Indemnitee. Indemnitee agrees promptly to notify the Company in writing upon being served with any
summons, citation, subpoena, complaint, indictment, information or other document relating to any Proceeding or matter which may be
subject to indemnification, reimbursement or advancement as provided hereunder. The failure of Indemnitee to so notify the Company
shall not relieve the Company of any obligation which it may have to Indemnitee under this Agreement or otherwise.

Section 19.     Notices. All notices, requests, demands and other communications under this Agreement shall be in writing and

shall be deemed to have been duly given if (i) delivered by hand and receipted for by the party to whom said notice or other
communication shall have been directed, (ii) mailed by certified or registered mail with postage prepaid, on the third business day after
the date on which it is so mailed, (iii) mailed by reputable overnight courier and receipted for by the party to whom said notice or other
communication shall have been directed or (iv) sent by facsimile transmission, with receipt of oral confirmation that such transmission has
been received:

(a)          If to Indemnitee, at such address as Indemnitee shall provide to the Company.

(b)          If to the Company to:

Viveve Medical, Inc.
150 Commercial Street
Sunnyvale, California 94086
Attention: Chief Executive Officer

or to any other address as may have been furnished to Indemnitee by the Company.

Section 20.     Contribution. To the fullest extent permissible under applicable law, if the indemnification provided for in this

Agreement is unavailable to Indemnitee for any reason whatsoever, the Company, in lieu of indemnifying Indemnitee, shall contribute to
the amount incurred by Indemnitee, whether for judgments, fines, penalties, excise taxes, amounts paid or to be paid in settlement and/or
for Expenses, in connection with any Proceeding in such proportion as is deemed fair and reasonable in light of all of the circumstances in
order to reflect (i) the relative benefits received by the Company and Indemnitee in connection with the event(s) and/or transaction(s)
giving rise to such Proceeding; and/or (ii) the relative fault of the Company (and its directors, officers, employees and agents) and
Indemnitee in connection with such event(s) and/or transactions.

Section 21.     Internal Revenue Code Section 409A. The Company intends for this Agreement to comply with the

Indemnification exception under Section 1.409A-1(b)(10) of the regulations promulgated under the Internal Revenue Code of 1986, as
amended (the “Code”), which provides that indemnification of, or the purchase of an insurance policy providing for payments of, all or
part of the expenses incurred or damages paid or payable by Indemnitee with respect to a bona fide claim against Indemnitee or the
Company do not provide for a deferral of compensation, subject to Section 409A of the Code, where such claim is based on actions or
failures to act by Indemnitee in his or her capacity as a service provider of the Company. The parties intend that this Agreement be
interpreted and construed with such intent.

12

 
 
 
 
 
 
 
 
 
 
Section 22.     Applicable Law and Consent to Jurisdiction. This Agreement and the legal relations among the parties shall be

governed by, and construed and enforced in accordance with, the laws of the State of Delaware, without regard to its conflict of laws rules.
Except with respect to any arbitration commenced by Indemnitee pursuant to Section 12(a) of this Agreement, the Company and
Indemnitee hereby irrevocably and unconditionally (i) agree that any action or proceeding arising out of or in connection with this
Agreement shall be brought only in the Delaware Court, and not in any other state or federal court in the United States of America or any
court in any other country, (ii) consent to submit to the exclusive jurisdiction of the Delaware Court for purposes of any action or
proceeding arising out of or in connection with this Agreement, (iii) consent to service of process at the address set forth in Section 19 of
this Agreement with the same legal force and validity as if served upon such party personally within the State of Delaware, (iv) waive any
objection to the laying of venue of any such action or proceeding in the Delaware Court, and (v) waive, and agree not to plead or to make,
any claim that any such action or proceeding brought in the Delaware Court has been brought in an improper or inconvenient forum.

Section 23.     Headings. The headings of the paragraphs of this Agreement are inserted for convenience only and shall not be

deemed to constitute part of this Agreement or to affect the construction thereof.

Section 24.     Identical Counterparts. This Agreement may be executed in one or more counterparts, each of which shall for all
purposes be deemed to be an original but all of which together shall constitute one and the same Agreement. Only one such counterpart
signed by the party against whom enforceability is sought needs to be produced to evidence the existence of this Agreement.

[Remainder of Page Intentionally Left Blank]

13

 
 
 
 
 
 
IN WITNESS WHEREOF, the parties have caused this Agreement to be signed as of the day and year first above written.

VIVEVE MEDICAL, INC.

By:  
  Name:   
Title:

[Name of Director]

[Signature Page to Indemnification Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
This Indemnification Agreement (“Agreement”) is made as of ________________ by and between Viveve Medical, Inc., a

Delaware corporation (the “Company”), and ____________ (“Indemnitee”).

INDEMNIFICATION AGREEMENT

RECITALS

WHEREAS, the Company desires to attract and retain the services of highly qualified individuals, such as Indemnitee, to serve

the Company;

WHEREAS, in order to induce Indemnitee to continue to provide services to the Company, the Company wishes to provide for

the indemnification of, and advancement of expenses to, Indemnitee to the maximum extent permitted by law;

WHEREAS, the Bylaws (the “Bylaws”) of the Company require indemnification of the officers and directors of the Company,

and Indemnitee may also be entitled to indemnification pursuant to the General Corporation Law of the State of Delaware (the “DGCL”);

WHEREAS, the Bylaws and the DGCL expressly provide that the indemnification provisions set forth therein are not exclusive,

and thereby contemplate that contracts may be entered into between the Company and members of the board of directors, officers and
other persons with respect to indemnification;

WHEREAS, the Board of Directors of the Company (the “ Board”) has determined that the increased difficulty in attracting and

retaining highly qualified persons such as Indemnitee is detrimental to the best interests of the Company’s stockholders;

WHEREAS, it is reasonable and prudent for the Company contractually to obligate itself to indemnify, and to advance expenses
on behalf of, such persons to the fullest extent permitted by applicable law, regardless of any amendment or revocation of the Bylaws, so
that they will continue to serve the Company free from undue concern that they will not be so indemnified; and

WHEREAS, this Agreement is a supplement to and in furtherance of the indemnification provided in the Bylaws and any

resolutions adopted pursuant thereto, and shall not be deemed a substitute therefor, nor to diminish or abrogate any rights of Indemnitee
thereunder.

NOW, THEREFORE, in consideration of the premises and the covenants contained herein, the Company and Indemnitee do

hereby covenant and agree as follows:

Section 1.      Services to the Company. Indemnitee agrees to serve as [a director and] an officer of the Company. Indemnitee may

at any time and for any reason resign from [any] such position (subject to any other contractual obligation or any obligation imposed by
law), in which event the Company shall have no obligation under this Agreement to continue Indemnitee in such position. This Agreement
shall not be deemed an employment contract between the Company (or any of its subsidiaries or any Enterprise) and Indemnitee.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Section 2.      Definitions.

As used in this Agreement:

(a)    [“Change in Control” shall mean:

(i)      the date any “person,” as such term is used in Sections 13(d) and 14(d) of the Securities Exchange Act of
1934, as amended (the “Act”) (other than the Company, any of its subsidiaries, or any trustee, fiduciary or other person or
entity holding securities under any employee benefit plan or trust of the Company or any of its subsidiaries), together with
all  “affiliates”  and  “associates”  (as  such  terms  are  defined  in  Rule  12b-2  under  the Act)  of  such  person,  becomes  the
“beneficial  owner”  (as  such  term  is  defined  in  Rule  13d-3  under  the Act),  directly  or  indirectly,  of  securities  of  the
Company  representing  fifty  percent  (50%)  or  more  of  the  combined  voting  power  of  the  Company’s  then  outstanding
securities having the right to vote in an election of the Board (“Voting Securities”) (in such case other than as a result of
an acquisition of securities directly from the Company); or

(ii)          the  date  a  majority  of  the  members  of  the  Board  is  replaced  during  any  12-month  period  by  directors
whose  appointment  or  election  is  not  endorsed  by  a  majority  of  the  members  of  the  Board  before  the  date  of  the
appointment or election; or

(iii)     the date of consummation of (A) any consolidation or merger of the Company where the stockholders of
the Company, immediately prior to the consolidation or merger, would not, immediately after the consolidation or merger,
beneficially own (as such term is defined in Rule 13d-3 under the Act), directly or indirectly, shares representing in the
aggregate more than fifty percent (50%) of the voting shares of the resulting or successor entity in the consolidation or
merger  (or  of  its  ultimate  parent  entity,  if  any),  or  (B)  any  sale  or  other  transfer  (in  one  transaction  or  a  series  of
transactions  contemplated  or  arranged  by  any  party  as  a  single  plan)  of  all  or  substantially  all  of  the  assets  of  the
Company on a consolidated basis to a person or entity not affiliated with the Company.]

(b)     “Corporate Status” describes the status of a person as a current or former [director or] officer of the Company or

current or former director, manager, partner, officer, employee, agent or trustee of any other Enterprise which such person is or was
serving at the request of the Company.

(c)     “Enforcement Expenses” shall include all reasonable attorneys’ fees, court costs, transcript costs, fees of experts,

travel expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees, and all other out-of-pocket
disbursements or expenses of the types customarily incurred in connection with an action to enforce indemnification or advancement
rights, or an appeal from such action. Expenses, however, shall not include fees, salaries, wages or benefits owed to Indemnitee.

2

 
 
 
 
 
 
 
 
 
 
(d)     “Enterprise” shall mean any corporation (other than the Company), partnership, joint venture, trust, employee
benefit plan, limited liability company, or other legal entity of which Indemnitee is or was serving at the request of the Company as a
director, manager, partner, officer, employee, agent or trustee.

(e)     “Expenses” shall include all reasonable attorneys’ fees, court costs, transcript costs, fees of experts, travel

expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees, and all other out-of-pocket
disbursements or expenses of the types customarily incurred in connection with prosecuting, defending, preparing to prosecute or defend,
investigating, being or preparing to be a witness in, or otherwise participating in, a Proceeding or an appeal resulting from a Proceeding.
Expenses, however, shall not include amounts paid in settlement by Indemnitee, the amount of judgments or fines against Indemnitee or
fees, salaries, wages or benefits owed to Indemnitee.

(f)     “Independent Counsel” means a law firm, or a partner (or, if applicable, member or shareholder) of such a law firm,

that is experienced in matters of Delaware corporation law and neither presently is, nor in the past five (5) years has been, retained to
represent: (i) the Company, any subsidiary of the Company, any Enterprise or Indemnitee in any matter material to any such party; or (ii)
any other party to the Proceeding giving rise to a claim for indemnification hereunder. Notwithstanding the foregoing, the term
“Independent Counsel” shall not include any person who, under the applicable standards of professional conduct then prevailing, would
have a conflict of interest in representing either the Company or Indemnitee in an action to determine Indemnitee’s rights under this
Agreement. The Company agrees to pay the reasonable fees and expenses of the Independent Counsel referred to above and to fully
indemnify such counsel against any and all expenses, claims, liabilities and damages arising out of or relating to this Agreement or its
engagement pursuant hereto.

(g)     The term “Proceeding” shall include any threatened, pending or completed action, suit, arbitration, alternate

dispute resolution mechanism, investigation, inquiry, administrative hearing or any other actual, threatened or completed proceeding,
whether brought in the right of the Company or otherwise and whether of a civil, criminal, administrative, regulatory or investigative
nature, and whether formal or informal, in which Indemnitee was, is or will be involved as a party or otherwise by reason of the fact that
Indemnitee is or was [a director or] an officer of the Company or is or was serving at the request of the Company as a director, manager,
partner, officer, employee, agent or trustee of any Enterprise or by reason of any action taken by Indemnitee or of any action taken on his
or her part while acting as [a director or] an officer of the Company or while serving at the request of the Company as a director, manager,
partner, officer, employee, agent or trustee of any Enterprise, in each case whether or not serving in such capacity at the time any liability
or expense is incurred for which indemnification, reimbursement or advancement of expenses can be provided under this Agreement;
provided, however, that the term “Proceeding” shall not include any action, suit or arbitration, or part thereof, initiated by Indemnitee to
enforce Indemnitee’s rights under this Agreement as provided for in Section 12(a) of this Agreement.

3

 
 
 
 
 
 
Section 3.     Indemnity in Third-Party Proceedings. The Company shall indemnify Indemnitee to the extent set forth in this

Section 3 if Indemnitee is, or is threatened to be made, a party to or a participant in any Proceeding, other than a Proceeding by or in the
right of the Company to procure a judgment in its favor. Pursuant to this Section 3, Indemnitee shall be indemnified against all Expenses,
judgments, fines, penalties, excise taxes, and amounts paid in settlement actually and reasonably incurred by Indemnitee or on his or her
behalf in connection with such Proceeding or any claim, issue or matter therein, if Indemnitee acted in good faith and in a manner he or she
reasonably believed to be in or not opposed to the best interests of the Company and, in the case of a criminal proceeding, had no
reasonable cause to believe that his or her conduct was unlawful.

Section 4.     Indemnity in Proceedings by or in the Right of the Company. The Company shall indemnify Indemnitee to the

extent set forth in this Section 4 if Indemnitee is, or is threatened to be made, a party to or a participant in any Proceeding by or in the right
of the Company to procure a judgment in its favor. Pursuant to this Section 4, Indemnitee shall be indemnified against all Expenses
actually and reasonably incurred by Indemnitee or on his or her behalf in connection with such Proceeding or any claim, issue or matter
therein, if Indemnitee acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best interests of the
Company. No indemnification for Expenses shall be made under this Section 4 in respect of any claim, issue or matter as to which
Indemnitee shall have been finally adjudged by a court to be liable to the Company, unless and only to the extent that the Delaware Court
of Chancery (the “Delaware Court”) shall determine upon application that, despite the adjudication of liability but in view of all the
circumstances of the case, Indemnitee is fairly and reasonably entitled to indemnification for such expenses as the Delaware Court shall
deem proper.

Section 5.     Indemnification for Expenses of a Party Who is Wholly or Partly Successful. Notwithstanding any other provisions
of this Agreement and except as provided in Section 7, to the extent that Indemnitee is a party to or a participant in any Proceeding and is
successful in such Proceeding or in defense of any claim, issue or matter therein, the Company shall indemnify Indemnitee against all
Expenses actually and reasonably incurred by him or her in connection therewith. If Indemnitee is not wholly successful in such
Proceeding but is successful as to one or more but less than all claims, issues or matters in such Proceeding, the Company shall indemnify
Indemnitee against all Expenses actually and reasonably incurred by Indemnitee or on his or her behalf in connection with each
successfully resolved claim, issue or matter. For purposes of this Section and without limitation, the termination of any claim, issue or
matter in such a Proceeding by dismissal, with or without prejudice, shall be deemed to be a successful result as to such claim, issue or
matter.

Section 6.     Reimbursement for Expenses of a Witness or in Response to a Subpoena. Notwithstanding any other provision of

this Agreement, to the extent that Indemnitee, by reason of his or her Corporate Status, (i) is a witness in any Proceeding to which
Indemnitee is not a party and is not threatened to be made a party or (ii) receives a subpoena with respect to any Proceeding to which
Indemnitee is not a party and is not threatened to be made a party, the Company shall reimburse Indemnitee for all Expenses actually and
reasonably incurred by him or her or on his or her behalf in connection therewith.

4

 
 
 
 
 
 
Section 7.     Exclusions. Notwithstanding any provision in this Agreement to the contrary, the Company shall not be obligated

under this Agreement:

(a)     to indemnify for amounts otherwise indemnifiable hereunder (or for which advancement is provided hereunder) if

and to the extent that Indemnitee has otherwise actually received such amounts under any insurance policy, contract, agreement or
otherwise;

(b)     to indemnify for an accounting of profits made from the purchase and sale (or sale and purchase) by Indemnitee of
securities of the Company within the meaning of Section 16(b) of the Securities Exchange Act of 1934, as amended, or similar provisions
of state statutory law or common law;

(c)     to indemnify for any reimbursement of, or payment to, the Company by Indemnitee of any bonus or other

incentive-based or equity-based compensation or of any profits realized by Indemnitee from the sale of securities of the Company pursuant
to Section 304 of SOX or any formal policy of the Company adopted by the Board (or a committee thereof), or any other remuneration
paid to Indemnitee if it shall be determined by a final judgment or other final adjudication that such remuneration was in violation of law;

(d)     to indemnify with respect to any Proceeding, or part thereof, brought by Indemnitee against the Company, any

legal entity which it controls, any director or officer thereof or any third party, unless (i) the Board has consented to the initiation of such
Proceeding or part thereof and (ii) the Company provides the indemnification, in its sole discretion, pursuant to the powers vested in the
Company under applicable law; provided, however, that this Section 7(d) shall not apply to (A) counterclaims or affirmative defenses
asserted by Indemnitee in an action brought against Indemnitee or (B) any action brought by Indemnitee for indemnification or
advancement from the Company under this Agreement or under any directors’ and officers’ liability insurance policies maintained by the
Company in the suit for which indemnification or advancement is being sought as described in Section 12; or

at the time payment would otherwise be required pursuant to this Agreement).

(e)     to provide any indemnification or advancement of expenses that is prohibited by applicable law (as such law exists

Section 8.     Advancement of Expenses. Subject to Section 9(b), the Company shall advance, to the extent not prohibited by law,
the Expenses incurred by Indemnitee in connection with any Proceeding, and such advancement shall be made within thirty (30) days after
the receipt by the Company of a statement or statements requesting such advances (including any invoices received by Indemnitee, which
such invoices may be redacted as necessary to avoid the waiver of any privilege accorded by applicable law) from time to time, whether
prior to or after final disposition of any Proceeding. Advances shall be unsecured and interest free. Advances shall be made without regard
to Indemnitee’s (i) ability to repay the expenses, (ii) ultimate entitlement to indemnification under the other provisions of this Agreement,
and (iii) entitlement to and availability of insurance coverage, including advancement, payment or reimbursement of defense costs,
expenses or covered loss under the provisions of any applicable insurance policy (including, without limitation, whether such
advancement, payment or reimbursement is withheld, conditioned or delayed by the insurer(s)). Indemnitee shall qualify for advances
upon the execution and delivery to the Company of this Agreement which shall constitute an undertaking providing that Indemnitee
undertakes to the fullest extent required by law to repay the advance if and to the extent that it is ultimately determined by a court of
competent jurisdiction in a final judgment, not subject to appeal, that Indemnitee is not entitled to be indemnified by the Company. The
right to advances under this paragraph shall in all events continue until final disposition of any Proceeding, including any appeal therein.
Nothing in this Section 8 shall limit Indemnitee’s right to advancement pursuant to Section 12(e) of this Agreement.

5

 
 
 
 
 
 
 
 
 
Section 9.     Procedure for Notification and Defense of Claim.

(a)     To obtain indemnification under this Agreement, Indemnitee shall submit to the Company a written request

therefor specifying the basis for the claim, the amounts for which Indemnitee is seeking payment under this Agreement, and all
documentation related thereto as reasonably requested by the Company.

(b)     In the event that the Company shall be obligated hereunder to provide indemnification for or make any

advancement of Expenses with respect to any Proceeding, the Company shall be entitled to assume the defense of such Proceeding, or any
claim, issue or matter therein, with counsel approved by Indemnitee (which approval shall not be unreasonably withheld or delayed) upon
the delivery to Indemnitee of written notice of the Company’s election to do so. After delivery of such notice, approval of such counsel by
Indemnitee and the retention of such counsel by the Company, the Company will not be liable to Indemnitee under this Agreement for any
fees or expenses of separate counsel subsequently employed by or on behalf of Indemnitee with respect to the same Proceeding; provided
that (i) Indemnitee shall have the right to employ separate counsel in any such Proceeding at Indemnitee’s expense and (ii) if (A) the
employment of separate counsel by Indemnitee has been previously authorized by the Company, (B) Indemnitee shall have reasonably
concluded that there may be a conflict of interest between the Company and Indemnitee in the conduct of such defense, or (C) the
Company shall not continue to retain such counsel to defend such Proceeding, then the fees and expenses actually and reasonably incurred
by Indemnitee with respect to his or her separate counsel shall be Expenses hereunder.

the Company will be entitled to participate in the Proceeding at its own expense.

(c)      In the event that the Company does not assume the defense in a Proceeding pursuant to paragraph (b) above, then

(d)      The Company shall not be liable to indemnify Indemnitee under this Agreement for any amounts paid in

settlement of any Proceeding effected without its prior written consent (which consent shall not be unreasonably withheld or delayed).
Without limiting the generality of the foregoing, the fact that an insurer under an applicable insurance policy delays or is unwilling to
consent to such settlement or is or may be in breach of its obligations under such policy, or the fact that directors’ and officers’ liability
insurance is otherwise unavailable or not maintained by the Company, may not be taken into account by the Company in determining
whether to provide its consent. The Company shall not, without the prior written consent of Indemnitee (which consent shall not be
unreasonably withheld or delayed), enter into any settlement which (i) includes an admission of fault of Indemnitee, any non-monetary
remedy imposed on Indemnitee or any monetary damages for which Indemnitee is not wholly and actually indemnified hereunder or (ii)
with respect to any Proceeding with respect to which Indemnitee may be or is made a party or may be otherwise entitled to seek
indemnification hereunder, does not include the full release of Indemnitee from all liability in respect of such Proceeding.

6

 
 
 
 
 
 
 
Section 10.     Procedure Upon Application for Indemnification .

(a)     Upon written request by Indemnitee for indemnification pursuant to Section 9(a), a determination, if such

determination is required by applicable law, with respect to Indemnitee’s entitlement to indemnification hereunder shall be made in the
specific case by one of the following methods: [(x) if a Change in Control shall have occurred and indemnification is being requested by
Indemnitee hereunder in his or her capacity as a director of the Company, by Independent Counsel in a written opinion to the Board; or (y)
in any other case,] (i) by a majority vote of the disinterested directors, even though less than a quorum; (ii) by a committee of disinterested
directors designated by a majority vote of the disinterested directors, even though less than a quorum; or (iii) if there are no disinterested
directors or if the disinterested directors so direct, by Independent Counsel in a written opinion to the Board. For purposes hereof,
disinterested directors are those members of the Board who are not parties to the action, suit or proceeding in respect of which
indemnification is sought. In the case that such determination is made by Independent Counsel, a copy of Independent Counsel’s written
opinion shall be delivered to Indemnitee and, if it is so determined that Indemnitee is entitled to indemnification, payment to Indemnitee
shall be made within thirty (30) days after such determination. Indemnitee shall cooperate with the Independent Counsel or the Company,
as applicable, in making such determination with respect to Indemnitee’s entitlement to indemnification, including providing to such
counsel or the Company, upon reasonable advance request, any documentation or information which is not privileged or otherwise
protected from disclosure and which is reasonably available to Indemnitee and reasonably necessary to such determination. Any out-of-
pocket costs or expenses (including reasonable attorneys’ fees and disbursements) actually and reasonably incurred by Indemnitee in so
cooperating with the Independent Counsel or the Company shall be borne by the Company (irrespective of the determination as to
Indemnitee’s entitlement to indemnification) and the Company hereby indemnifies and agrees to hold Indemnitee harmless therefrom.

(b)     If the determination of entitlement to indemnification is to be made by Independent Counsel pursuant to Section

10(a), the Independent Counsel shall be selected by the Board[; provided that, if a Change in Control shall have occurred and
indemnification is being requested by Indemnitee hereunder in his or her capacity as a director of the Company, the Independent Counsel
shall be selected by Indemnitee]. Indemnitee [or the Company, as the case may be,] may, within ten (10) days after written notice of such
selection, deliver to the Company [or Indemnitee, as the case may be,] a written objection to such selection; provided, however, that such
objection may be asserted only on the ground that the Independent Counsel so selected does not meet the requirements of “Independent
Counsel” as defined in Section 2 of this Agreement, and the objection shall set forth with particularity the factual basis of such assertion.
Absent a proper and timely objection, the person so selected shall act as Independent Counsel. If such written objection is so made and
substantiated, the Independent Counsel so selected may not serve as Independent Counsel unless and until such objection is withdrawn or
the Delaware Court has determined that such objection is without merit. If, within twenty (20) days after the later of (i) submission by
Indemnitee of a written request for indemnification pursuant to Section 9(a), and (ii) the final disposition of the Proceeding, including any
appeal therein, no Independent Counsel shall have been selected without objection, either Indemnitee or the Company may petition the
Delaware Court for resolution of any objection which shall have been made by Indemnitee or the Company to the selection of Independent
Counsel and/or for the appointment as Independent Counsel of a person selected by the court or by such other person as the court shall
designate. The person with respect to whom all objections are so resolved or the person so appointed shall act as Independent Counsel
under Section 10(a) hereof. Upon the due commencement of any judicial proceeding or arbitration pursuant to Section 12(a) of this
Agreement, Independent Counsel shall be discharged and relieved of any further responsibility in such capacity (subject to the applicable
standards of professional conduct then prevailing).

7

 
 
 
 
 
(c)     Notwithstanding anything to the contrary contained in this Agreement, the determination of entitlement to

indemnification under this Agreement shall be made without regard to the Indemnitee’s entitlement to and availability of insurance
coverage, including advancement, payment or reimbursement of defense costs, expenses or covered loss under the provisions of any
applicable insurance policy (including, without limitation, whether such advancement, payment or reimbursement is withheld, conditioned
or delayed by the insurer(s)).

Section 11.     Presumptions and Effect of Certain Proceedings.

(a)     To the extent permitted by applicable law, in making a determination with respect to entitlement to indemnification

hereunder, it shall be presumed that Indemnitee is entitled to indemnification under this Agreement if Indemnitee has submitted a request
for indemnification in accordance with Section 9(a) of this Agreement, and the Company shall have the burden of proof to overcome that
presumption in connection with the making of any determination contrary to that presumption.

(b)     The termination of any Proceeding or of any claim, issue or matter therein, by judgment, order, settlement or

conviction, or upon a plea of guilty, nolo contendere or its equivalent, shall not (except as otherwise expressly provided in this Agreement)
of itself adversely affect the right of Indemnitee to indemnification or create a presumption that Indemnitee did not act in good faith and in
a manner which he or she reasonably believed to be in or not opposed to the best interests of the Company or, with respect to any criminal
Proceeding, that Indemnitee had reasonable cause to believe that his or her conduct was unlawful.

(c)     The knowledge and/or actions, or failure to act, of any director, manager, partner, officer, employee, agent or

trustee of the Company, any subsidiary of the Company, or any Enterprise shall not be imputed to Indemnitee for purposes of determining
the right to indemnification under this Agreement.

8

 
 
 
 
 
 
 
Section 12.     Remedies of Indemnitee.

(a)     Subject to Section 12(f), in the event that (i) a determination is made pursuant to Section 10 of this Agreement that
Indemnitee is not entitled to indemnification under this Agreement, (ii) advancement of Expenses is not timely made pursuant to Section 8
of this Agreement, (iii) no determination of entitlement to indemnification shall have been made pursuant to Section 10(a) of this
Agreement within sixty (60) days after receipt by the Company of the request for indemnification for which a determination is to be made
other than by Independent Counsel, (iv) payment of indemnification or reimbursement of expenses is not made pursuant to Section 5 or 6
or the last sentence of Section 10(a) of this Agreement within thirty (30) days after receipt by the Company of a written request therefor
(including any invoices received by Indemnitee, which such invoices may be redacted as necessary to avoid the waiver of any privilege
accorded by applicable law) or (v) payment of indemnification pursuant to Section 3 or 4 of this Agreement is not made within thirty (30)
days after a determination has been made that Indemnitee is entitled to indemnification, Indemnitee shall be entitled to an adjudication by
the Delaware Court of his or her entitlement to such indemnification or advancement. Alternatively, Indemnitee, at his or her option, may
seek an award in arbitration to be conducted by a single arbitrator pursuant to the Commercial Arbitration Rules of the American
Arbitration Association. Indemnitee shall commence such proceeding seeking an adjudication or an award in arbitration within 180 days
following the date on which Indemnitee first has the right to commence such proceeding pursuant to this Section 12(a); provided, however,
that the foregoing time limitation shall not apply in respect of a proceeding brought by Indemnitee to enforce his or her rights under
Section 5 of this Agreement. The Company shall not oppose Indemnitee’s right to seek any such adjudication or award in arbitration.

(b)     In the event that a determination shall have been made pursuant to Section 10(a) of this Agreement that Indemnitee

is not entitled to indemnification, any judicial proceeding or arbitration commenced pursuant to this Section 12 shall be conducted in all
respects as a de novo trial, or arbitration, on the merits and Indemnitee shall not be prejudiced by reason of that adverse determination. In
any judicial proceeding or arbitration commenced pursuant to this Section 12, the Company shall have the burden of proving Indemnitee is
not entitled to indemnification or advancement, as the case may be.

(c)      If a determination shall have been made pursuant to Section 10(a) of this Agreement that Indemnitee is entitled to
indemnification, the Company shall be bound by such determination in any judicial proceeding or arbitration commenced pursuant to this
Section 12, absent (i) a misstatement by Indemnitee of a material fact, or an omission of a material fact necessary to make Indemnitee’s
statement not materially misleading, in connection with the request for indemnification, or (ii) a prohibition of such indemnification under
applicable law.

(d)     The Company shall be precluded from asserting in any judicial proceeding or arbitration commenced pursuant to

this Section 12 that the procedures and presumptions of this Agreement are not valid, binding and enforceable and shall stipulate in any
such court or before any such arbitrator that the Company is bound by all the provisions of this Agreement.

(e)     The Company shall indemnify Indemnitee to the fullest extent permitted by law against any and all Enforcement

Expenses and, if requested by Indemnitee, shall (within thirty (30) days after receipt by the Company of a written request therefor)
advance, to the extent not prohibited by law, such Enforcement Expenses to Indemnitee, which are incurred by Indemnitee in connection
with any action brought by Indemnitee for indemnification or advancement from the Company under this Agreement or under any
directors’ and officers’ liability insurance policies maintained by the Company in the suit for which indemnification or advancement is
being sought. Such written request for advancement shall include invoices received by Indemnitee in connection with such Enforcement
Expenses but, in the case of invoices in connection with legal services, any references to legal work performed or to expenditures made
that would cause Indemnitee to waive any privilege accorded by applicable law need not be included with the invoice.

9

 
 
 
 
 
 
 
 
under this Agreement shall be required to be made prior to the final disposition of the Proceeding, including any appeal therein.

(f)     Notwithstanding anything in this Agreement to the contrary, no determination as to entitlement to indemnification

Section 13.     Non-exclusivity; Survival of Rights; Insurance; Subrogation .

(a)     The rights of indemnification and to receive advancement as provided by this Agreement shall not be deemed

exclusive of any other rights to which Indemnitee may at any time be entitled under applicable law, the Charter, the Bylaws, any
agreement, a vote of stockholders or a resolution of directors, or otherwise. No amendment, alteration or repeal of this Agreement or of
any provision hereof shall limit or restrict any right of Indemnitee under this Agreement in respect of any action taken or omitted by such
Indemnitee in his or her Corporate Status prior to such amendment, alteration or repeal. To the extent that a change in Delaware law,
whether by statute or judicial decision, permits greater indemnification or advancement than would be afforded currently under the Bylaws
and this Agreement, it is the intent of the parties hereto that Indemnitee shall enjoy by this Agreement the greater benefits so afforded by
such change. No right or remedy herein conferred is intended to be exclusive of any other right or remedy, and every other right and
remedy shall be cumulative and in addition to every other right and remedy given hereunder or now or hereafter existing at law or in
equity or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise, shall not prevent the concurrent
assertion or employment of any other right or remedy.

(b)     To the extent that the Company maintains an insurance policy or policies providing liability insurance for

directors, managers, partners, officers, employees, agents or trustees of the Company or of any other Enterprise, Indemnitee shall be
covered by such policy or policies in accordance with its or their terms to the maximum extent of the coverage available for any such
director, manager, partner, officer, employee, agent or trustee under such policy or policies. If, at the time of the receipt of a notice of a
claim pursuant to the terms hereof, the Company has director and officer liability insurance in effect, the Company shall give prompt
notice of the commencement of such proceeding to the insurers in accordance with the procedures set forth in the respective policies.

(c)     In the event of any payment under this Agreement, the Company shall be subrogated to the extent of such payment
to all of the rights of recovery of Indemnitee, who shall execute all papers required and take all action necessary to  secure  such  rights,
including execution of such documents as are necessary to enable the Company to bring suit to enforce such rights.

10

 
 
 
 
 
 
 
(d)     The Company’s obligation to provide indemnification or advancement hereunder to Indemnitee who is or was

serving at the request of the Company as a director, manager, partner, officer, employee, agent or trustee of any other Enterprise shall be
reduced by any amount Indemnitee has actually received as indemnification or advancement from such other Enterprise.

Section 14.      Duration of Agreement. This Agreement shall continue until and terminate upon the later of: (a) ten (10) years after

the date that Indemnitee shall have ceased to serve as [both a director and] an officer of the Company or (b) one (1) year after the final
termination of any Proceeding, including any appeal, then pending in respect of which Indemnitee is granted rights of indemnification or
advancement hereunder and of any proceeding commenced by Indemnitee pursuant to Section 12 of this Agreement relating thereto. This
Agreement shall be binding upon the Company and its successors and assigns and shall inure to the benefit of Indemnitee and his or her
heirs, executors and administrators. The Company shall require and cause any successor (whether direct or indirect by purchase, merger,
consolidation or otherwise) to all, substantially all or a substantial part, of the business and/or assets of the Company, by written
agreement in form and substance satisfactory to Indemnitee, expressly to assume and agree to perform this Agreement in the same manner
and to the same extent that the Company would be required to perform if no such succession had taken place.

Section 15.     Severability. If any provision or provisions of this Agreement shall be held to be invalid, illegal or unenforceable
for any reason whatsoever: (a) the validity, legality and enforceability of the remaining provisions of this Agreement (including, without
limitation, each portion of any section of this Agreement containing any such provision held to be invalid, illegal or unenforceable, that is
not itself invalid, illegal or unenforceable) shall not in any way be affected or impaired thereby and shall remain enforceable to the fullest
extent permitted by law; (b) such provision or provisions shall be deemed reformed to the extent necessary to conform to applicable law
and to give the maximum effect to the intent of the parties hereto; and (c) to the fullest extent possible, the provisions of this Agreement
(including, without limitation, each portion of any section of this Agreement containing any such provision held to be invalid, illegal or
unenforceable, that is not itself invalid, illegal or unenforceable) shall be construed so as to give effect to the intent manifested thereby.

Section 16.     Enforcement.

(a)     The Company expressly confirms and agrees that it has entered into this Agreement and assumed the obligations
imposed on it hereby in order to induce Indemnitee to continue to serve as [a director and] an officer of the Company, and the Company
acknowledges that Indemnitee is relying upon this Agreement in serving as [a director and] an officer of the Company.

(b)     This Agreement constitutes the entire agreement between the parties hereto with respect to the subject matter

hereof and supersedes all prior agreements and understandings, oral, written and implied, between the parties hereto with respect to the
subject matter hereof; provided, however, that this Agreement is a supplement to and in furtherance of the Charter, the Bylaws and
applicable law, and shall not be deemed a substitute therefor, nor to diminish or abrogate any rights of Indemnitee thereunder.

11

 
 
 
 
 
 
 
 
Section 17.     Modification and Waiver. No supplement, modification or amendment, or waiver of any provision, of this
Agreement shall be binding unless executed in writing by the parties thereto. No waiver of any of the provisions of this Agreement shall
be deemed or shall constitute a waiver of any other provisions of this Agreement nor shall any waiver constitute a continuing waiver. No
supplement, modification or amendment of this Agreement or of any provision hereof shall limit or restrict any right of Indemnitee under
this Agreement in respect of any action taken or omitted by such Indemnitee prior to such supplement, modification or amendment.

Section 18.     Notice by Indemnitee. Indemnitee agrees promptly to notify the Company in writing upon being served with any
summons, citation, subpoena, complaint, indictment, information or other document relating to any Proceeding or matter which may be
subject to indemnification, reimbursement or advancement as provided hereunder. The failure of Indemnitee to so notify the Company
shall not relieve the Company of any obligation which it may have to Indemnitee under this Agreement or otherwise.

Section 19.     Notices. All notices, requests, demands and other communications under this Agreement shall be in writing and

shall be deemed to have been duly given if (i) delivered by hand and receipted for by the party to whom said notice or other
communication shall have been directed, (ii) mailed by certified or registered mail with postage prepaid, on the third business day after
the date on which it is so mailed, (iii) mailed by reputable overnight courier and receipted for by the party to whom said notice or other
communication shall have been directed or (iv) sent by facsimile transmission, with receipt of oral confirmation that such transmission has
been received:

(a)          If to Indemnitee, at such address as Indemnitee shall provide to the Company.

(b)          If to the Company to:

Viveve Medical, Inc.
150 Commercial Street
Sunnyvale, California 94086
Attention: Chief Executive Officer

or to any other address as may have been furnished to Indemnitee by the Company.

Section 20.     Contribution. To the fullest extent permissible under applicable law, if the indemnification provided for in this

Agreement is unavailable to Indemnitee for any reason whatsoever, the Company, in lieu of indemnifying Indemnitee, shall contribute to
the amount incurred by Indemnitee, whether for judgments, fines, penalties, excise taxes, amounts paid or to be paid in settlement and/or
for Expenses, in connection with any Proceeding in such proportion as is deemed fair and reasonable in light of all of the circumstances in
order to reflect (i) the relative benefits received by the Company and Indemnitee in connection with the event(s) and/or transaction(s)
giving rise to such Proceeding; and/or (ii) the relative fault of the Company (and its directors, officers, employees and agents) and
Indemnitee in connection with such event(s) and/or transactions.

12

 
 
 
 
 
 
 
 
 
 
Section 21.     Internal Revenue Code Section 409A. The Company intends for this Agreement to comply with the

Indemnification exception under Section 1.409A-1(b)(10) of the regulations promulgated under the Internal Revenue Code of 1986, as
amended (the “Code”), which provides that indemnification of, or the purchase of an insurance policy providing for payments of, all or
part of the expenses incurred or damages paid or payable by Indemnitee with respect to a bona fide claim against Indemnitee or the
Company do not provide for a deferral of compensation, subject to Section 409A of the Code, where such claim is based on actions or
failures to act by Indemnitee in his or her capacity as a service provider of the Company. The parties intend that this Agreement be
interpreted and construed with such intent.

Section 22.     Applicable Law and Consent to Jurisdiction. This Agreement and the legal relations among the parties shall be

governed by, and construed and enforced in accordance with, the laws of the State of Delaware, without regard to its conflict of laws rules.
Except with respect to any arbitration commenced by Indemnitee pursuant to Section 12(a) of this Agreement, the Company and
Indemnitee hereby irrevocably and unconditionally (i) agree that any action or proceeding arising out of or in connection with this
Agreement shall be brought only in the Delaware Court, and not in any other state or federal court in the United States of America or any
court in any other country, (ii) consent to submit to the exclusive jurisdiction of the Delaware Court for purposes of any action or
proceeding arising out of or in connection with this Agreement, (iii) consent to service of process at the address set forth in Section 19 of
this Agreement with the same legal force and validity as if served upon such party personally within the State of Delaware, (iv) waive any
objection to the laying of venue of any such action or proceeding in the Delaware Court, and (v) waive, and agree not to plead or to make,
any claim that any such action or proceeding brought in the Delaware Court has been brought in an improper or inconvenient forum.

Section 23.     Headings. The headings of the paragraphs of this Agreement are inserted for convenience only and shall not be

deemed to constitute part of this Agreement or to affect the construction thereof.

Section 24.     Identical Counterparts. This Agreement may be executed in one or more counterparts, each of which shall for all
purposes be deemed to be an original but all of which together shall constitute one and the same Agreement. Only one such counterpart
signed by the party against whom enforceability is sought needs to be produced to evidence the existence of this Agreement.

[Remainder of Page Intentionally Left Blank]

13

 
 
 
 
 
 
 
IN WITNESS WHEREOF, the parties have caused this Agreement to be signed as of the day and year first above written.

VIVEVE MEDICAL, INC.

By:  
  Name:
Title:

[Name of Indemnitee]

[Signature Page to Indemnification Agreement]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

Exhibit 23.1

We hereby consent to the incorporation by referenc e in the Registration Statements on Form S-3 (No. 333-221432 and 333-213682) and
Form S-8 (Nos. 333-220833, 333-213363, 333-206041, 333-201551, 333-153535 and 333-127770) of Viveve Medical, Inc. of our reports
dated March 15, 2018 relating to the consolidated financial statements and internal control over financial reporting, which appear in this
Annual Report on Form 10-K.

/s/ BPM LLP

San Jose, California
March 15, 2018

 
 
 
 
 
 
Exhibit 31.1

Certification of Chief Executive Officer
Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

I, Patricia Scheller, certify that:

1. I have reviewed this Annual Report on Form 10-K for Viveve Medical, Inc.;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to
make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period
covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material
respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as
defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules
13a-15(f) and 15d-15(f)) for the registrant and have:

a.  Designed  such  disclosure  controls  and  procedures,  or  caused  such  disclosure  controls  and  procedures  to  be  designed  under  our
supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by
others within those entities, particularly during the period in which this report is being prepared;

b. Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our
supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for
external purposes in accordance with generally accepted accounting principles;

c. Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the
effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

d. Disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most
recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely
to materially affect, the registrant's internal control over financial reporting; and

5. The registrant's other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial
reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent
functions):

a. All  significant  deficiencies  and  material  weaknesses  in  the  design  or  operation  of  internal  control  over  financial  reporting  which  are
reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

b. Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal
control over financial reporting.

Date: March 15, 2018

/s/ Patricia Scheller
Patricia Scheller
Chief Executive Officer
(Principal Executive Officer)

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
Exhibit 31.2

Certification of Chief Financial Officer
Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

I, Scott Durbin, certify that:

1. I have reviewed this Annual Report on Form 10-K for Viveve Medical, Inc.;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to
make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period
covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material
respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as
defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules
13a-15(f) and 15d-15(f)) for the registrant and have:

a.  Designed  such  disclosure  controls  and  procedures,  or  caused  such  disclosure  controls  and  procedures  to  be  designed  under  our
supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by
others within those entities, particularly during the period in which this report is being prepared;

b. Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our
supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for
external purposes in accordance with generally accepted accounting principles;

c. Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the
effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

d. Disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most
recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely
to materially affect, the registrant's internal control over financial reporting; and

5. The registrant's other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial
reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent
functions):

a. All  significant  deficiencies  and  material  weaknesses  in  the  design  or  operation  of  internal  control  over  financial  reporting  which  are
reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

b. Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal
control over financial reporting.

Date: March 15, 2018

/s/ Scott Durbin
Scott Durbin
Chief Financial Officer
(Principal Financial and Accounting Officer)

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
Certification
Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
(Subsections (A) and (B) of Section 1350, Chapter 63 of Title 18,
United States Code)

Exhibit 32.1

Pursuant to section 906 of the Sarbanes-Oxley Act of 2002 (subsections (a) and (b) of section 1350, chapter 63 of Title 18, United States
Code),  the  undersigned  officer  of  Viveve  Medical,  Inc.  (the  “Company”),  does  hereby  certify  with  respect  to  the Annual  Report  of  the
Company  on  Form  10-K  for  the  period  ended  December  31,  2017  as  filed  with  the  Securities  and  Exchange  Commission  on  the  date
hereof (the “Report”), that:

(1) The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the
Company.

Date: March 15, 2018

/s/ Patricia Scheller
Patricia Scheller
Chief Executive Officer
(Principal Executive Officer)

 
 
 
 
 
 
 
 
 
 
 
  
 
 
Certification
Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
(Subsections (A) and (B) of Section 1350, Chapter 63 of Title 18,
United States Code)

Exhibit 32.2

Pursuant to section 906 of the Sarbanes-Oxley Act of 2002 (subsections (a) and (b) of section 1350, chapter 63 of Title 18, United States
Code),  the  undersigned  officer  of  Viveve  Medical,  Inc.  (the  “Company”),  does  hereby  certify  with  respect  to  the Annual  Report  of  the
Company  on  Form  10-K  for  the  period  ended  December  31,  2017  as  filed  with  the  Securities  and  Exchange  Commission  on  the  date
hereof (the “Report”), that:

(1) The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the
Company.

Date: March 15, 2018

/s/ Scott Durbin
Scott Durbin
Chief Financial Officer
(Principal Financial and Accounting Officer)