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Cynata Therapeutics Limited
Annual Report 2024

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FY2024 Annual Report · Cynata Therapeutics Limited
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Cynata Therapeutics Limited 
Office:  L3 100 Cubitt St, Cremorne, VIC 3121, Australia 
T: +61 3 7067 6940 W:  www.cynata.com 
ABN 98 104 037 372 
Appendix 4E 
Annual financial report for the year ended 30 June 2025 
1.
Details of reporting period
Name of entity 
Cynata Therapeutics Limited (the Company) 
ABN 
98 104 037 372 
Reporting Period 
Year ended 30 June 2025 
Previous Corresponding Period 
Year ended 30 June 2024 
Presentation Currency 
Australian Dollars ($) 
2.
Results for announcement to the market
Key information 
30 June 2025 
$ 
30 June 2023 
$ 
Increase/ 
(decrease) 
% 
Amount 
change 
$ 
Revenues from ordinary activities 
2,112,839 
2,733,353 
(22.70%) 
(620,514) 
Loss from ordinary activities after tax 
attributable to members 
9,390,586 
9,744,709 
(3.63%) 
(354,123) 
Net loss for the period attributable to 
members 
9,390,586 
9,744,709 
(3.63%) 
(354,123) 
Net tangible asset per share 
0.018 
0.030 
- 
- 
3.
Consolidated statement of profit or loss and other comprehensive income
Refer to attached consolidated financial statements. 
4.
Consolidated statement of financial position
Refer to attached consolidated financial statements. 
5.
Consolidated statement of cash flows
Refer to attached consolidated financial statements. 
6.
Consolidated statement of changes in equity
Refer to attached consolidated financial statements. 
7.
Dividends/Distributions
No dividends declared in current or prior year. 
8.
Details of dividend reinvestment plans
Not applicable. 

9.
Details of entities over which control has been gained or lost during the period
Not applicable. 
10. Details of associate and joint venture entities
Not applicable. 
11. Any other significant information needed by an investor to make an informed
assessment of the Company’s financial performance and financial position
Refer to attached consolidated financial statements. 
12. Foreign entities
Refer to attached consolidated financial statements. 
13. Commentary on results for period and explanatory information
Cynata Therapeutics Limited (“Cynata” or the “Company”) and its controlled entities (“the Group”) incurred a 
net loss from operations for the financial year ended 30 June 2025 of $9,390,586 (2024: $9,774,709) after 
accounting for an R&D refund of $1,885,140 (2024: $2,315,643).  At 30 June 2025, the Group had a cash balance 
of $5,049,744 (2024: $6,205,418) and net assets of $5,981,735 (2024: $7,217,235).  The net cash outflow from 
operating activities for the financial year was $8,720,335 (2024: $9,960,561).  Cynata is in a phase of significant 
momentum, with one clinical trial completed during the 2025 financial year and three more progressing towards 
results in the 2026 financial year. The Phase 1 clinical trial in DFU is complete with CYP-006TK demonstrated to 
be safe and well tolerated, and positive efficacy data indicating substantially improved wound healing compared 
to the standard of care control group.  The Phase 2 trial in aGvHD is ~85% enrolled with patient recruitment 
progressing and primary results anticipated during H1 2026.  The fully enrolled, 321-patient Phase 3 trial in 
Osteoarthritis is nearing completion with top-line results anticipated between February and April 2026.  Cohort 
1 of the Phase 1/2 kidney transplant trial has completed treatment, with DMSB review results expected in Q4 
2025.  The Company remains well-capitalised with funding runway through mid-2026, covering all key clinical 
readouts. 
For more information, refer to the attached consolidated financial statements. 
14. Audit
This report is based on accounts which have been audited. The Auditor’s Report contains an unqualified 
audit opinion with an ‘Emphasis of Matter’ paragraph drawing attention to a material uncertainty that 
may cast a significant doubt about the Group’s ability to continue as a going concern. The attached 
consolidated financial statements have been prepared on a going concern basis.  Please refer to note 3. 
Dr Kilian Kelly 
Managing Director & Chief Executive Officer 
28 August 2025 

Annual Report
2024/2025

Cynata Therapeutics Limited
ACN 104 037 372
Corporate Directory
Board of Directors
Dr Geoff Brooke
Non-Executive Chair
Dr Kilian Kelly
Managing Director &
Chief Executive Officer
Dr Darryl Maher
Non-Executive Director
Dr Paul Wotton
Non-Executive Director
Ms Janine Rolfe
Non-Executive Director
Company Secretary
Mr Peter Webse
Registered Office and
Principal Place of Business 
Level 3, 100 Cubitt Street
Cremorne, Victoria 3121
Tel: 	
+61 3 7067 6940
Email: 	info@cynata.com
Website
www.cynata.com
Auditors
Stantons
Level 2, 40 Kings Park Road
West Perth, Western Australia 6005
Share Registry
Automic Registry Services
Level 5, 191 St Georges Terrace
Perth, Western Australia 6000
Tel: 	
1300 288 664 (within Australia)	
	
+61 2 9698 5414 (outside Australia)
Fax:	
+61 8 9321 2337
Email:	hello@automic.com.au
Web: 	 www.automic.com.au
Stock Exchange
Australian Securities Exchange
Level 50, South Tower, Rialto
525 Collins Street
Melbourne, Victoria 3000
ASX Code
CYP – fully paid ordinary shares
Annual report for the 
financial year ended
30 June 2025

1

1
Contents
Key Highlights 2024-2025	
3
Chair’s Letter	
4
CEO’s Letter	
6
Directors’ Report	
8
Operating and Financial Review	
18
Remuneration Report (audited)	
24
Auditor’s Independence Declaration	
38
Independent Auditor’s Report	
39
Directors’ Declaration	
43
Financial Statements	
46
Notes	
52
Consolidated Entity Disclosure Statement	
80
ASX Additional Information  	
82

2
Cynata Therapeutics Annual Report 2024/2025

3
Key Highlights 2024-2025
Key Highlights 2024-2025
Cynata is in a phase of 
significant momentum, with 
one clinical trial completed 
during the 2025 financial year, 
and three more progressing 
towards results in the 2026 
financial year
The Phase 2 trial in aGvHD is 
~85% enrolled, with patient 
recruitment progressing and 
primary results anticipated 
during H1 2026
Scientific paper underlining 
strengths of Cymerus™ 
platform relative to 
conventional manufacturing 
methods published in leading 
peer-reviewed journal
The Company remains well-
capitalised with funding 
runway through mid-2026, 
covering all key clinical 
readouts
The Phase 1 clinical trial 
in DFU is complete, with 
CYP-006TK demonstrated to 
be safe and well tolerated, 
and positive efficacy data 
indicating substantially 
improved wound healing 
compared to the standard 
of care control group
Upcoming clinical milestones 
have the potential to 
represent inflection points for 
valuation, partnering, and 
product approval pathways
The fully enrolled, 321-patient 
Phase 3 trial in Osteoarthritis 
is nearing completion in the 
coming months, with top-line 
results anticipated between 
February and April 2026
Cohort 1 of the Phase 1/2 
kidney transplant trial has 
completed treatment, with 
review results expected in 
Q4 2025
Positive efficacy results 
in preclinical models of 
pulmonary fibrosis and 
ischaemic heart disease, 
supporting potential 
expansion into large 
additional markets
TM

4
Cynata Therapeutics Annual Report 2024/2025
Chair’s Letter
Dear Shareholders,
Cynata is entering what I believe will be the most pivotal year in our 
history. Within the next 12 months, we expect results from three 
clinical trials — each with the potential to transform treatment in 
large, high-need markets and significantly enhance the Company’s 
value.
Our strategy is to develop multiple 
advanced cell-based therapies for 
serious diseases with limited or no 
effective treatment options. These 
are produced using our globally 
unique and highly scalable Cymerus 
manufacturing platform, which creates 
mesenchymal stem cells (MSCs) 
from induced pluripotent stem cells 
(iPSCs). This approach overcomes 
the manufacturing and consistency 
challenges that have constrained the 
industry for decades.
The market for scalable regenerative 
medicine solutions is growing rapidly, 
supported by powerful tailwinds: 
the global maturation of MSC clinical 
trials, increasing regulatory support 
through Fast Track and Orphan 
Drug pathways, and rising demand 
driven by ageing populations and the 
burden of chronic disease. Cynata is 
exceptionally well placed to lead in this 
environment.
Over the 2025 financial year, the team 
made strong progress across our 
pipeline. We reported encouraging 
results from our Phase 1 diabetic foot 
ulcer trial and advanced three further 
clinical programs towards readouts 
in the coming year. For a company 
of our size, to be on the verge of 
delivering results from three separate 
trials — in acute graft versus host 
disease, osteoarthritis, and kidney 
transplantation — is a remarkable 
achievement. We also advanced our 
preclinical programs, opening the door 
to future opportunities in additional 
major indications.
The market for 
scalable regenerative 
medicine solutions 
is growing rapidly, 
supported by 
powerful tailwinds

5
Chair’s Letter
We believe the true value of our platform and 
programs will be increasingly recognised as these 
milestones are achieved. Each program holds promise 
not only for patients living with these challenging 
conditions but also for the long-term growth and 
success of the Company.
On behalf of the Board, I thank our shareholders for 
their continued support and the entire Cynata team 
for their commitment to delivering on our vision. The 
year ahead will be a defining one — and together, 
we are poised to translate years of innovation into 
breakthrough results for patients and enduring value 
for our investors.
Yours sincerely,
Dr Geoff Brooke
Chair

6
Cynata Therapeutics Annual Report 2024/2025
Dear Shareholders,
The 2025 financial year was defined by disciplined execution and 
significant progress across our portfolio, positioning Cynata for a 
pivotal year ahead. We advanced every one of our active clinical 
programs, strengthened our preclinical pipeline, and ensured the 
financial capacity to deliver on our next set of major milestones.
We successfully completed our Phase 
1 clinical trial of CYP-006TK in diabetic 
foot ulcers. The trial met its primary 
safety objective and generated strong 
efficacy data, with substantially 
greater wound healing than the 
standard of care, particularly in larger 
wounds where treatment options are 
limited. These results have initiated 
engagement with potential commercial 
partners and informed our planning for 
the next stage of development.
Our global Phase 2 trial of CYP-001 
in newly diagnosed, high-risk acute 
graft versus host disease is now 
approximately 85% enrolled. This 
program builds on a highly successful 
Phase 1 trial published in Nature 
Medicine and is on track to deliver 
its primary results in the first half 
of calendar 2026. Meanwhile, the 
University of Sydney-led Phase 3 trial 
of CYP-004 in osteoarthritis of the knee 
completed enrolment of 321 patients. 
Follow-up is progressing as planned, 
with final results expected between 
February and April 2026.
In Europe, the first cohort in our Phase 
1/2 kidney transplantation trial at 
Leiden University Medical Center 
has completed treatment, with an 
independent safety review scheduled 
for the fourth quarter of 2025. This 
study aims to demonstrate the 
potential of CYP-001 to reduce the 
need for long-term immunosuppressive 
therapy following transplant.
We also advanced our preclinical 
programs, generating positive efficacy 
The year ahead will 
see three major trial 
results — kidney 
transplantation in 
Q4 2025, aGvHD 
in H1 2026, and 
osteoarthritis in 
early 2026 — 
each representing 
a significant 
opportunity to drive 
value creation.
CEO’s Letter

7
CEO’s Letter
results in models of pulmonary fibrosis and heart 
attack, and publishing peer-reviewed data confirming 
that our Cymerus iPSC-derived MSCs are less variable 
and have functional advantages over MSCs from 
other sources. These outcomes further strengthen our 
scientific and manufacturing position.
Financially, we remain well-capitalised, having 
secured a $1.88 million R&D Tax Incentive rebate and 
completed an $8.10 million institutional placement 
during the year. With a cash balance of $5 million 
at year-end and the 2025 rebate expected shortly, 
we have a funding runway through to mid-2026 — 
comfortably covering all upcoming clinical readouts. 
Furthermore, the At-The-Market subscription 
agreement announced subsequent to the year end 
provides the Company with up to $7.5 million of 
standby equity capital over the next five years, which 
provides us with additional flexibility. Importantly, two 
of our late-stage trials are externally funded, allowing 
us to concentrate our resources on programs with the 
greatest strategic value.
The year ahead will see three major trial results — 
kidney transplantation in Q4 2025, aGvHD in H1 2026, 
and osteoarthritis in early 2026 — each representing 
a significant opportunity to drive value creation. Our 
operational focus remains squarely on delivering these 
milestones on schedule and positioning Cynata to 
capitalise on positive outcomes.
Thank you for your continued support as we work to 
translate our innovations into tangible benefits for 
patients and lasting value for our shareholders.
Yours sincerely, 
Dr Kilian Kelly
Chief Executive Officer & Managing Director

8
Cynata Therapeutics Annual Report 2024/2025
Directors’ Report
The directors of Cynata Therapeutics Limited (“Cynata” 
or “the Company”) and its controlled entities (“the Group”) 
submit herewith the annual report of the Group for the 
financial year ended 30 June 2025. 
In order to comply with the provisions of the 
Corporations Act 2001, the directors report as follows:

9
Directors’ Report
Board of Directors
The names and particulars of the directors of the Group during or since the end of 
the financial year are:
Dr Geoff Brooke
MBBS, MBA
Independent Chair, joined the Board 
in May 2019 as Non-Executive 
Director and appointed Chair on 18 
August 2020. Dr Brooke co-founded 
GBS Venture Partners in 1996 and 
has more than 30 years’ venture 
capital experience. He was formerly 
President of Medvest Inc., a US-based 
early-stage venture capital group he 
founded with Johnson & Johnson.  Dr 
Brooke’s experience includes company 
formation and acquisitions as well as 
public listings on NYSE, NASDAQ and 
ASX exchanges.  He is a non-executive 
director of Acrux Limited (ASX: ACR) 
and Chair of Actinogen Medical Limited 
(ASX: ACW) and has been a founder, 
executive and director of private and 
public companies.  From 2009 until 
2015, Dr Brooke was an independent 
director of the Victoria Workcover 
Authority. He also works with a 
number of other entities, including as a 
consultant to BioScience Managers. Dr 
Brooke holds a Bachelor of Medicine/
Surgery from Melbourne University and 
a Masters of Business Administration 
from IMEDE (now IMD) in Switzerland.
Dr Kilian Kelly
MPharm, PhD, GAICD
Managing Director & Chief Executive 
Officer as from 1 July 2023.  Dr Kelly 
was appointed as Vice President, 
Product Development in January 2014 
and has since then been a member 
of Cynata’s executive management 
team.  Dr Kelly has served as Senior 
Director, Drug Development at 
Biota Pharmaceuticals Inc.  Prior to 
joining Biota, he was Vice President, 
Regulatory and Clinical at Mesoblast 
Ltd.  Dr Kelly has also held a variety of 
regulatory and project management 
positions with Kendle International, 
Amgen and AstraZeneca. He holds 
a Masters in Pharmacy from Robert 
Gordon University, Aberdeen and a 
PhD in Pharmaceutical Sciences from 
Strathclyde University, Glasgow.  He 
is a registered pharmacist and a 
member of the Royal Pharmaceutical 
Society, a graduate and member of 
the Australian Institute of Company 
Directors (AICD), a member of the 
International Society for Cell and Gene 
Therapy (ISCT) and the International 
Society for Stem Cell Research (ISSCR). 
He also currently serves on the ISCT 
Asia-Pacific Industry Committee, 
the ISSCR Best Practices Regulatory 
Working Group and the Industry 
Interface Committee of the Centre for 
Commercialisation of Regenerative 
Medicine (CCRM) Australia.

10
Cynata Therapeutics Annual Report 2024/2025
Dr Darryl Maher
MBBS, PhD
Independent Non-Executive Director, 
joined the Board in June 2020. Dr Maher 
adds global biopharmaceutical and 
commercialisation capability to the 
Cynata board, with over 23 years’ 
experience with CSL Limited. CSL is 
one of the world’s most successful 
developers of biologic pharmaceutical 
products and has a market 
capitalisation of ~A$130 billion. 
Dr Maher has had a long successful 
career in pharmaceutical product 
development, most recently as the 
former Vice President of R&D and 
Medical Affairs at CSL Behring 
Australia where he was responsible for 
the development of multiple successful 
drug products from initiation through 
to clinical development and ultimately 
to commercialisation. Dr Maher 
undertook medical training, qualified 
as a specialist haematologist and 
completed a PhD before commencing 
his career in the pharmaceutical 
industry.
Dr Paul Wotton
MBA, PhD
Independent Non-Executive Director, 
joined the Board in June 2016.  He is 
the Executive Chairman of the Biotech 
LaunchPad at Rice University, Houston. 
He was President and CEO of Obsidian 
Therapeutics, Founding CEO of Sigilon 
Therapeutics (acquired by Lilly) and 
President and CEO of Ocata 
Therapeutics, Inc. (NASDAQ: OCAT) 
which was acquired by Astellas in 
2016.  Prior to Ocata, Dr Wotton had 
served as President and CEO of 
Antares Pharma Inc. (NASDAQ: ATRS).  
Prior to joining Antares, Dr Wotton was 
the CEO of Topigen Pharmaceuticals. 
Earlier in his career, he held senior level 
executive positions at SkyePharma plc, 
Eurand International BV, Penwest 
Pharmaceuticals, Abbott Laboratories 
and Merck, Sharp and Dohme.  
Dr Wotton is a member of the board of 
Vericel Corporation (NASDAQ: VCEL), 
Chairman of Dimension Inx., and 
Chairman of Kytopen Inc.  Dr Wotton 
received his Ph.D. in pharmaceutical 
sciences from the University of 
Nottingham. In 2014, he was named EY 
Entrepreneur of the Year (NJ) in Life 
Sciences.
Directors’ Report (cont’d)

11
Directors’ Report
Ms Janine Rolfe
BEc, LLB (Hons), GAICD
Independent Non-Executive Director, 
joined the Board in September 
2022.  Ms Rolfe brings more than 
two decades of legal, governance 
and management experience across 
multiple sectors, including highly 
regulated industries and complex 
global businesses. Ms Rolfe is a 
professional non-executive director 
and currently sits on the boards of 
Ambertech Limited (ASX: AMO) and 
Cloudwerx Holdings Pty Ltd.  
Ms Rolfe is also a commissioner for the 
NSW Independent Casino Commission, 
a statutory authority. Previously, Ms 
Rolfe was General Counsel & Company 
Secretary of Link Group.  Prior to that, 
Ms Rolfe founded the governance 
consultancy, Company Matters, and 
worked both as in-house counsel 
at Qantas and in private practice at 
Mallesons Stephen Jaques (now King & 
Wood Mallesons).

12
Cynata Therapeutics Annual Report 2024/2025
12
Directors’ Report (cont’d)
Directorships of other listed companies
Directorships of other listed companies held by directors in the 3 years immediately before the end of the financial 
year are as follows:
Name
Company
Period of directorship
Geoff Brooke
Acrux Limited
Since Jun 2016
Actinogen Medical Limited
Since Mar 2017
Paul Wotton
Vericel Corporation
Since 2015
Janine Rolfe
Ambertech Limited
Since Sept 2023
Directors’ shareholdings
The following table sets out each director’s relevant interest in shares, rights or options in shares or debentures of 
the Company or a related body corporate as at the date of this report:
Fully paid ordinary shares
Share options
Directors
No.
No.
Geoff Brooke
312,898
2,500,000
Kilian Kelly
797,428
2,750,000
Darryl Maher
116,666
520,000
Paul Wotton
585,076
520,000
Janine Rolfe
255,167
520,000
Remuneration of key management 
personnel
Information about the remuneration of key 
management personnel (“KMP”) is set out in the 
remuneration report section of this directors’ report. 
The term ‘key management personnel’ refers to 
those persons having authority and responsibility for 
planning, directing and controlling the activities of 
the Group, directly or indirectly, including any director 
(whether executive or otherwise) of the Group.
Options granted to directors and 
senior management
No options were granted to directors and key 
management personnel during and since the end of 
the financial year (2024: 4,210,000).

13
Directors’ Report
13
Company Secretary
Mr Peter Webse held the position of company 
secretary of Cynata Therapeutics Limited at the end 
of the financial year. He joined Cynata in April 2012. 
Mr Webse is a director of Governance Corporate Pty 
Ltd, a company specialising in providing company 
secretarial, corporate governance and corporate 
advisory services. Mr Webse acts as Company 
Secretary for a number of ASX listed biotech and 
technology companies.
Dividends
No dividends have been paid or declared since the 
start of the financial year and the directors have not 
recommended the payment of a dividend in respect of 
the financial year.
Shares under option or issued on exercise of options
Details of unissued shares or interests under option as at the date of this report are:
Issuing entity
Grant date
Number of 
shares under 
option
Class of shares
Exercise price 
of option
Expiry date of 
options
Cynata Therapeutics Limited1
24 Nov 2020
4,500,000
Ordinary
$0.970
29 Nov 2025
Cynata Therapeutics Limited2
11 Oct 2021
1,000,000
Ordinary
$0.890
11 Oct 2025
Cynata Therapeutics Limited3
22 Nov 2022
300,000
Ordinary
$0.510
23 Nov 2027
Cynata Therapeutics Limited4
30 Jun 2023
2,033,333
Ordinary
$0.176
30 Jun 2028
Cynata Therapeutics Limited5
13 Nov 2023
1,910,000
Ordinary
$0.185
20 Nov 2028
Cynata Therapeutics Limited6
16 Jan 2024
975,000
Ordinary
$0.195
16 Jan 2029
Cynata Therapeutics Limited7
17 Apr 2024
1,800,000
Ordinary
$0.290
17 Apr 2029
Cynata Therapeutics Limited8
13 Sept 2024
1,000,000
Ordinary
$0.280
12 Sept 2028
Cynata Therapeutics Limited9
1 Oct 2024
1,000,000
Ordinary
$0.300
2 Apr 2026
Cynata Therapeutics Limited9
1 Oct 2024
1,000,000
Ordinary
$0.400
2 Apr 2026
Cynata Therapeutics Limited9
1 Oct 2024
1,000,000
Ordinary
$0.500
2 Apr 2026
Cynata Therapeutics Limited10
10 Jun 2025
500,000
Ordinary
$0.400
10 Sept 2026
Cynata Therapeutics Limited10
10 Jun 2025
750,000
Ordinary
$0.500
10 Sept 2026
Cynata Therapeutics Limited10
10 Jun 2025
1,750,000
Ordinary
$0.600
10 Sept 2026
1	
Unlisted options issued to Dr Brooke (2,000,000), 
Dr Macdonald (1,500,000), Dr Washer (300,000), Dr Wotton 
(300,000), Dr Maher (300,000) and Mr Webse (100,000) on 30 
November 2020 pursuant to an Employee Option Acquisition 
Plan. Dr Macdonald retired from the Board on 30 June 2023 
and Dr Washer ceased to be a director on 1 July 2023.
2	
Unlisted options issued to Dr Airey on 11 October 2021 
pursuant to an Employee Option Acquisition Plan.
3	
Unlisted options issued to Ms Rolfe on 23 November 2022 
in consideration of her agreeing to join the Board and to 
reward her expected future commitment and contribution as a 
director.

14
Cynata Therapeutics Annual Report 2024/2025
14
Directors’ Report (cont’d)
4	
Unlisted options issued to Dr Kelly (2,000,000) pursuant to the 
terms of his appointment on 1 July 2023 as Managing Director 
& CEO following the retirement of Dr Ross Macdonald.  Dr 
Kelly was previously the Chief Operating Officer of Cynata.  
Dr Atkins resigned on 13 November 2023 and as a result, 
266,667 options were cancelled on his resignation.
5	
Unlisted options issued to Dr Brooke (500,000), Dr Kelly 
(750,000), Dr Maher (220,000), Ms Rolfe (220,000) and Dr 
Wotton (220,000) to ensure alignment with shareholders’ 
interests and to maximise Company value.
6	
Unlisted options issued to Dr Airey (500,000), Mr Webse 
(125,000) and other employees of the Company (350,000) 
pursuant to an Employee Option Acquisition Plan.
7	
Unlisted options issued to Dr Kroll pursuant to an Employee 
Option Acquisition Plan.
8	
Unlisted options issued to an external consultant under 
Cynata Equity Incentive Plan in lieu of payment of fees.
9	
Unlisted options issued to the lead broker of the Institutional 
Placement pursuant to a Corporate Advisory Mandate.  These 
options were issued for $0.00001 per option and Cynata 
received $30 cash for these options.
10	 Unlisted options issued to the lead broker of the Institutional 
Placement pursuant to a Corporate Advisory Mandate.  These 
options were issued for $0.00001 per option and Cynata 
received $30 cash for these options.

The holders of these options do not have the right, by 
virtue of the option, to participate in any share issue 
or interest issue of the Company or of any other body 
corporate or registered scheme.
Details of shares or interests issued during or since the end of the financial year as a result of the exercise of an 
option are set out in the table below (2024: 3,150):
Issuing entity
Number of 
shares issued
Class of shares
Amount paid
for shares
Amount unpaid 
on shares
Cynata Therapeutics Limited
72,917
Ordinary
$0.300
$nil
Directors’ meetings
The following table sets out the number of directors’ meetings held during the financial year and the number of 
meetings attended by each director.  During the financial year, 7 board meetings were held.
Board of Directors
Directors
Held
Attended
Geoff Brooke
7
7
Kilian Kelly
7
7
Paul Wotton
7
7
Darryl Maher
7
7
Janine Rolfe
7
7

15
Directors’ Report
15
Indemnification of officers and 
auditors
The Company indemnifies each of its Directors, 
Officers and Company Secretary. The Company 
indemnifies each Director or officer to the maximum 
extent permitted by the Corporations Act 2001 from 
liability to third parties, except where the liability 
arises out of conduct involving lack of good faith and 
in defending legal and administrative proceedings and 
applications for such proceedings.
The Company must use its best endeavours to insure 
a Director or Officer against any liability, which does 
not arise out of conduct constituting a wilful breach of 
duty or a contravention of the Corporations Act 2001.  
The Company must also use its best endeavours to 
insure a Director of Officer against liability for costs 
and expenses incurred in defending proceedings 
whether civil or criminal.
The Company has not entered into any agreement 
with its current auditors indemnifying them against 
any claims by third parties arising from their provision 
of audit services.
Insurance premiums
During the year, the Company paid insurance 
premiums to insure directors and officers against 
certain liabilities arising out of their conduct while 
acting as an officer of the Group.  Under the terms 
and conditions of the insurance contract, the nature 
of the liabilities insured against and the premium paid 
cannot be disclosed.
Proceedings on behalf of the 
Company
No person has applied for leave of Court to bring 
proceedings on behalf of the Company or intervene in 
any proceedings to which the Company is a party for 
the purpose of taking responsibility on behalf of the 
Company for all or any part of those proceedings.
Changes in state of affairs
There was no significant change in the state of affairs 
of the Group during the financial year.
Subsequent events
On 22 August 2025, the Company entered into an 
At-the-Market Subscription Agreement (“ATM”) with 
Acuity Capital. The ATM provides Cynata with up to 
$7,500,000 of standby equity capital over the coming 
five years, to 31 July 2030.  Cynata has full discretion 
as to whether or not to utilise the ATM, the maximum 
number of shares to be issued, the minimum issue 
price of shares and the timing of each subscription 
(if any). Cynata may terminate the ATM at any time, 
without cost or penalty. As security, the Company has 
issued 11,500,000 fully paid ordinary shares in the 
Company at nil cash consideration.
Other than the above, there has not been any matter 
or circumstance occurring subsequent to the end of 
the financial year that has significantly affected, or 
may significantly affect, the operations of the Group, 
the results of those operations, or state of affairs of 
the Group in future financial years.
Corporate governance
Cynata Therapeutics Limited and the board support 
and adhere to the principles of corporate governance 
and are committed to achieving and demonstrating 
the highest standards of corporate governance.  
Cynata has reviewed its corporate governance 
practices against the Corporate Governance Principles 
and Recommendations (4th edition) published by 
the ASX Corporate Governance Council.  The 2025 
Corporate Governance Statement is dated 28 August 
2025 and reflects the corporate governance practices 
in place throughout the 2025 financial year.  The 2025 
Corporate Governance Statement was approved by 
the board on 28 August 2025. A description of the 
Group’s current corporate governance practices is set 
out in the Group’s Corporate Governance Statement 
which can be viewed at www.cynata.com/corporate-
governance.

16
Cynata Therapeutics Annual Report 2024/2025
16
Directors’ Report (cont’d)
Environmental regulations
The Group’s operations are not subject to significant 
environmental regulation under the Australian 
Commonwealth or State law.  
Non-audit services
The auditor did not perform any non-audit services 
during the financial year.
Auditor’s independence declaration
The auditor’s independence declaration for the 
financial year ended 30 June 2025 has been received 
and is included on page 40 of this annual report.

17

18
Cynata Therapeutics Annual Report 2024/2025
18
Principal activities
The Group’s principal activities throughout the 
financial year continued to be the development and 
commercialisation of a proprietary induced pluripotent 
stem cell (iPSC)-based platform technology, Cymerus.
Operating results
The consolidated loss of the Group for the financial 
year, after accounting for an R&D refund of 
$1,885,140 (2024: $2,315,643) and providing 
for income tax, amounted to $9,390,586 (2024: 
$9,744,709). Further discussion on the Group’s 
operations is provided below:
Operational update
Diabetic Foot Ulcer (DFU) – Phase 1 Trial Complete 
with Positive Results
Due to reduced blood flow, patients with diabetes are 
at risk of developing non-healing wounds on the feet/
lower limbs, which are also known as diabetic foot 
ulcers or DFU. In addition to causing severe pain and 
discomfort, DFU pose a significant risk of infection, 
and if treatment is unsuccessful, amputation may be 
necessary.
CYP-006TK is Cynata’s Cymerus iPSC-derived 
MSC topical wound dressing product candidate, 
which comprises MSCs seeded onto a novel silicone 
dressing. This product was investigated as a potential 
treatment to promote wound healing in patients with 
DFU in a Phase 1 clinical trial, which was completed 
during the year.
The trial met its primary objective, with CYP-006TK 
found to be safe and well-tolerated – no participants 
withdrew from the trial due to adverse events, and 
there were no suspected serious adverse reactions 
reported. 
Importantly, the trial also generated positive 
efficacy data, indicating improved wound healing 
for CYP‑006TK compared to the standard of care 
control group. After 12 weeks, there was a mean 
(average) decrease in wound surface area of 64.6% 
in the CYP-006TK group compared to a decrease of 
22.0% in the standard of care control group. After 
24 weeks, there was a mean decrease of 83.6% in the 
CYP‑006TK group compared to a decrease of 47.8% 
in the standard of care control group. The results also 
indicated that larger wounds in particular healed to a 
greater extent in the CYP-006TK group compared to 
the standard of care control group.
Given the high unmet need in DFU and the strength 
of these results, Cynata is actively engaging potential 
commercial partners and planning further clinical 
development.
Operating and Financial Review

19
Operating and Financial Review
19
Acute Graft versus Host Disease (aGvHD) – Phase 2 
Trial ~85% enrolled; Results Expected H1 2026
aGvHD is a serious and often life-threatening 
complication of bone marrow transplantation and 
similar procedures (also known as haematopoietic 
stem cell transplantation [HSCT] or blood stem cell 
transplantation). aGvHD arises when immune cells 
in the transplant (the graft) recognise the recipient’s 
tissues (the host) as “foreign”.  It affects up to 50% of 
HSCT patients. Standard first-line treatment is with 
corticosteroids, but around half of all cases do not 
respond, and the historical two-year survival rate in 
steroid-resistant patients is less than 20%.1 
CYP-001 is Cynata’s Cymerus off-the-shelf iPSC-
derived MSC product for intravenous infusion. It 
is designed to modulate the immune system and 
improve both response rates and survival outcomes 
in aGvHD. The US FDA has granted Orphan Drug 
Designation2 to CYP-001 for the treatment of aGvHD, 
potentially providing several commercially significant 
incentives and decreased time to commercialisation. 
In a successful Phase 1 trial in patients with steroid-
resistant aGvHD, after treatment with CYP-001, 87% 
of patients improved by at least one grade, 53% 
showed no signs of aGvHD, and 60% were alive at 
two years. Importantly, there were no serious adverse 
events related to treatment, and the results were 
published in the prestigious journal Nature Medicine.3,4 
Cynata is now conducting a global Phase 2 trial at 
centres in the USA, Europe and Australia, enrolling 
approximately 60 patients with high-risk newly-
diagnosed aGvHD. Patients are randomised to receive 
either standard steroid therapy plus CYP-001, or 
steroids plus placebo. The primary endpoint is overall 
response at Day 28. Patient enrolment progressed 
very well during the year, and at the time of writing 
1	 Westin JR et al. Adv Hematol. 2011:601953 (2011)
2	 Orphan Drug Designation qualifies Cynata for incentives 
including extended marketing exclusivity, tax credits and fee 
waivers.
3	 Bloor AJC et al. Nat Med. 26:1720–1725 (2020).
4	 Kelly K et al. Nat Med. 30:1556–1558 (2024).
Review of operations
Key Highlights
Cynata is in a phase of significant 
momentum, with one clinical trial completed 
during the 2025 financial year, and three 
more progressing towards results in the 
2026 financial year
The Phase 1 clinical trial in DFU is complete, 
with CYP-006TK demonstrated to be safe 
and well tolerated, and positive efficacy data 
indicating substantially improved wound 
healing compared to the standard of care 
control group
The Phase 2 trial in aGvHD is ~85% enrolled, 
with patient recruitment progressing and 
primary results anticipated during H1 2026
The fully enrolled, 321-patient Phase 3 trial 
in Osteoarthritis is nearing completion in 
the coming months, with top-line results 
anticipated between February and April 2026
Cohort 1 of the Phase 1/2 kidney transplant 
trial has completed treatment, with review 
results expected in Q4 2025
Positive efficacy results in preclinical models 
of pulmonary fibrosis and ischaemic heart 
disease, supporting potential expansion into 
large additional markets
Scientific paper underlining strengths of 
Cymerus platform relative to conventional 
manufacturing methods published in leading 
peer-reviewed journal
Upcoming clinical milestones have the 
potential to represent inflection points for 
valuation, partnering, and product approval 
pathways 
The Company remains well-capitalised with 
funding runway through mid-2026, covering 
all key clinical readouts

20
Cynata Therapeutics Annual Report 2024/2025
20
Operating and Financial Review (cont’d)
is now ~85% complete. The Company anticipates 
completing enrolment in the coming months and 
releasing the primary results during H1 2026. 
Osteoarthritis – Phase 3 Trial Recruitment Complete; 
Results Expected Feb-Apr 2026
Osteoarthritis is a degenerative joint condition 
affecting over 500 million people globally. 
Current treatment options are limited to symptom 
management or invasive surgery, with no therapies 
available that address cartilage loss and inflammation 
at the source.
CYP-004 is Cynata’s Cymerus off-the-shelf iPSC-
derived MSC product for intra-articular injection 
(injection into a joint). The ongoing Phase 3 trial of 
CYP-004 in patients with osteoarthritis of the knee, 
known as the SCUlpTOR5 trial, is being conducted 
by the University of Sydney and funded through an 
NHMRC project grant. The trial completed enrolment 
of 321 patients in November 2023, with all patients 
now having received their study treatments. Follow-
up is ongoing, with final 24-month results anticipated 
between February and April 2026. The trial has 
co-primary outcome measures, which aim to show 
the effects of CYP-004 on both symptoms (pain) and 
disease progression (cartilage thickness as measured 
by MRI6). If successful, this could be the first ever 
disease-modifying treatment for osteoarthritis.
Additionally, during the year, the Company held an 
advisory meeting with the Australian Therapeutic 
Goods Administration (TGA), and based on the advice 
received, Cynata is optimistic that positive results from 
this trial could support marketing approval of CYP-004 
in Australia.
Renal Transplantation – First Cohort Complete; 
Results of DSMB Review Expected Q4 2025
Patients undergoing kidney transplantation typically 
require lifelong immunosuppressive therapy with 
calcineurin inhibitor drugs to prevent rejection of the 
5	 SCUlpTOR = Stem Cells as a symptom- and strUcture-modifying Treatment for medial tibiofemoral OsteoaRthritis
6	 MRI = magnetic resonance imaging
transplanted organ. Calcineurin inhibitors are quite 
effective at preventing rejection, but they come with 
serious long-term toxicity and health risks.
This investigator-led 16 patient trial, conducted 
at Leiden University Medical Centre (LUMC) in the 
Netherlands, is assessing whether CYP-001 can 
reduce reliance on calcineurin inhibitors, potentially 
offering patients safer long-term immune modulation. 
The enrolment and treatment of the three patients in 
Cohort 1 is now complete. Once the third and final 
patient treated in this cohort is followed up for six 
weeks, the study’s independent Data and Safety 
Monitoring Board (DSMB) will review the data from 
this Cohort. The results of this review are anticipated 
by Q4 2025.
Finance
The net assets of the Group have decreased by 
$1,235,500 to $5,981,735 in 2025 (2024: $7,217,235).
During the year, Cynata received a Research and 
Development Tax Incentive rebate of $1.88m from 
the Australian Federal Government and further 
strengthened its balance sheet with an $8.10m (before 
costs) institutional placement in December 2024.
Notably, the Company is now only funding one ongoing 
clinical trial (its Phase 2 aGvHD trial). The other ongoing 
trials (in kidney transplantation and osteoarthritis) are 
being conducted by partners and funded externally. 
Furthermore, the Company anticipates receiving its 
2025 Research and Development Tax Incentive rebate 
in the coming months.
The Company anticipates its cash runway to extend 
into mid calendar year 2026, beyond the anticipated 
renal transplantation, aGvHD and osteoarthritis 
clinical trial readouts.

21
Operating and Financial Review
21
Outlook
Cynata is entering one of the most important phases 
in its history — a 12-month window in which three 
clinical trials will deliver results. 
Before the end of 2025, we expect to report 
safety review results from our Phase 1/2 kidney 
transplantation trial, which could demonstrate a 
pathway to reducing long-term immunosuppressive 
therapy in transplant patients. 
In the first half of 2026, we anticipate primary results 
from our global Phase 2 trial in acute graft versus 
host disease, building on world-class data from our 
earlier study and targeting a high-value, high-need 
market. Shortly after, between February and April 
2026, we look forward to the final results of the 
University of Sydney-led Phase 3 osteoarthritis trial, 
which, if successful, could position CYP-004 as the 
first disease-modifying treatment for one of the most 
common joint diseases in the world. Clinical validation 
in these late-stage clinical trials will soon also spark 
parallel development in more diseases with high 
unmet medical need. 
We aim to unlock the full potential of the Cymerus 
technology through our advanced clinical and 
preclinical pipelines and partnered development. 
We have deliberately focused on markets where 
demand is proven, competition is limited, and our 
manufacturing advantages can set a new global 
standard. Very few companies of our size have the 
potential to deliver this breadth of high-impact data 
in such a short period of time. With the support of our 
shareholders, Cynata is excited to convert years of 
innovation into transformative products for patients — 
and lasting growth and value for our investors. 
Material risks
There is a small number of material risks that, either 
individually or in combination, may materially and 
adversely affect the future operating and financial 
performance and prospects of Cynata and the value 
of its shares.  Some of these risks may be mitigated 
by Cynata’s internal controls and processes but 
some are outside the control of Cynata, its directors 
and management.  The material risks identified by 
management are described below:
(a) Clinical development risk
The nature of clinical drug development is inherently 
risky, with many drug candidates failing to be 
successfully developed into marketable products. 
The Company is currently undertaking clinical trials 
with certain of its products and plans to undertake 
trials with additional products in its pipeline. Clinical 
trials have many associated risks which may impact 
the Company’s commercial potential and therefore 
its future prospects and profitability. Clinical trials 
may fail to recruit patients, be terminated for safety 
reasons, or fail to be completed within acceptable 
timeframes as a result of delay. Clinical trials may 
reveal drug candidates to be unsafe, poorly tolerated 
or non-effective. Any of these outcomes will likely 
have a significant adverse effect on the Company, 
the value of its securities and the future commercial 
development of its drug candidates. Clinical trials 
might also potentially expose the Company to product 
liability claims in the event its products in development 
have unexpected effects on clinical subjects.
Mitigation measures employed by the Company 
include: ensuring that clinical trials are strongly 
supported by preclinical safety and efficacy data; 
careful clinical trial design to minimise the changes 
of potentially spurious outcomes; use of independent 
data and safety monitoring boards; engagement of 
leading contract research organisations to manage 
the trials and drive recruitment; engagement of 
well-qualified clinical sites experienced in clinical trial 
execution and in the relevant therapeutic areas.

22
Cynata Therapeutics Annual Report 2024/2025
22
Operating and Financial Review (cont’d)
(b) Regulatory risk
The research, development, manufacture, marketing 
and sale of products developed by the Company are 
subject to extensive regulation by multiple government 
authorities and institutional bodies in Australia and 
overseas. Pharmaceutical products must undergo a 
comprehensive and highly regulated development, 
trial and review process before receiving approval for 
marketing. The process includes a requirement for 
approval to conduct clinical trials, and the provision of 
data relating to the quality, safety and efficacy of the 
products for their proposed use. There is no guarantee 
that regulatory approvals to conduct clinical trials 
and/or to manufacture and market the Company’s 
products will be granted.
If a product is approved, it may also be submitted for 
cost reimbursement approval to relevant agencies. The 
availability and timing of that reimbursement approval 
may have an impact upon the uptake and profitability 
of products in some jurisdictions. If the Company is 
unable to secure necessary approvals from regulatory 
agencies and institutional bodies to undertake its 
planned trials, market its products and obtain cost 
reimbursements for its products its future prospects 
and profitability is likely to be materially and adversely 
affected.
Mitigation measures employed by the Company 
include: engagement of suitably qualified and 
experienced persons with expertise in the regulation 
of biological/cellular therapies; regular review of 
evolving regulatory requirements and analysis of the 
Company’s activities and plans against regulatory 
expectations in key jurisdictions; and ensuring that the 
expectations and uncertainties related to regulatory 
approvals, and the timing of such approvals, are 
included in business plans. 
(c) Risks associated with partnership model
The Company is pursuing a license partnership 
model, which typically involves entering into 
commercial arrangements with other companies 
by which Cynata licenses its Cymerus technology 
to the partner in one or more indications and/or 
geographies and the partner assumes responsibility 
for progressing, and paying for, the clinical trials and 
eventual commercialisation in that indication. This 
strategy involves the risk that the Company will lose 
control of the development timetable of its products 
to its commercial partner, which may give rise to 
an unanticipated delay in any commercial returns. 
Further, the Company may be unable to enter into 
arrangements with suitable commercial partners 
in respect of relevant indications. If either of these 
outcomes occurred, the Company’s business and 
operations may be adversely affected.
Mitigation measures employed by the Company 
include: performing rigorous due diligence on potential 
partners; ensuring that the commercial terms 
negotiated are fair and utilising expert legal advice to 
ensure that appropriate warranties and commitments 
are included in contracts, and that the contracts reflect 
the agreed commercial position, and the creation of 
the Chief Business Officer position with executive 
responsibility for the Company’s partnerships.
(d) Reliance on in-licensed assets
The Company relies on patents and intellectual 
property that is in-licensed from Wisconsin Alumni 
Research Foundation (WARF) and Cellular Dynamics 
International, Inc (now an affiliate of Fujifilm 
Corporation). These assets are not owned outright 
by Cynata. The license arrangements contain terms 
and conditions, including obligations to make certain 
milestone and royalty payments.
In the event that the Company breaches any of the 
licence terms and conditions and cannot rectify the 
breach within an appropriate time, there is a risk that 
the licence may be terminated and the Company could 
lose control of its assets. This would have a significant 
adverse impact on the Company.
Mitigation measures employed by the Company 
include: utilising expert professional advice in respect 
of all of the Company’s commercial arrangements; 
actively monitoring licence terms and obligations; 
implementing product development strategies to 
achieve milestones; financial management to ensure 
that the Company can meet all financial obligations to 
licensors. 

23
Operating and Financial Review
23
(e) Manufacturing risk
The Company’s products are manufactured using a 
unique, novel and highly specialised manufacturing 
process. The Company relies on supply and 
manufacturing relationships with third party contract 
manufacturing organisations to manufacture its 
products. An inability of these third-party contract 
manufacturing organisations to continue to 
manufacture the Company’s products in a timely, 
economical and/or consistent manner, including any 
scale up of manufacturing processes, or to maintain 
legally compliant manufacturing to maintain product 
supply, could adversely impact on the progress of the 
Company’s development programs and potentially on 
the financial performance of the Company.
Mitigation measures employed by the Company 
include: performing rigorous due diligence on contract 
manufacturers; engaging contract manufacturers with 
strong track records and sufficient capability to meet 
the Company’s foreseeable needs; and employing 
a senior manager responsible for managing and 
monitoring the performance of third parties including 
contract manufacturers.

24
Cynata Therapeutics Annual Report 2024/2025
24
This remuneration report, which forms part 
of the directors’ report, sets out information 
about the remuneration of Cynata 
Therapeutics Limited’s key management 
personnel (“KMP”) for the financial year 
ended 30 June 2025. 
The term ‘key management personnel’ refers to 
those persons having authority and responsibility for 
planning, directing and controlling the activities of 
the Group, directly or indirectly, including any director 
(whether executive or otherwise) of the Group.
Remuneration Report (audited)
Contents
The prescribed details for each person 
covered by this report are detailed below 
under the following headings:
1.	Key management personnel
2.	Remuneration policy
	
(a)	 Non-executive director remuneration
	
(b)	 Executive director remuneration
	
(c)	 Equity settled compensation
3.	Relationship between the remuneration 
policy and Company performance
4.	Remuneration of key management 
personnel
(a)	 Bonus and share-based payments 
granted as compensation for the 
current financial year
(i)	 Bonuses
(ii)	 Incentive share-based payment 
arrangements
5.	Key terms of employment contracts
6.	Key management personnel equity 
holdings

25
Remuneration Report (audited)
25
1. 	Key management personnel
The directors and other KMP of the Group during or since the end of the financial year were:
Non-executive directors
Position
Dr Geoff Brooke
Independent Non-Executive Chair
Dr Darryl Maher
Independent Non-Executive Director
Dr Paul Wotton
Independent Non-Executive Director
Ms Janine Rolfe
Independent Non-Executive Director
Executive directors
Position
Dr Kilian Kelly
Managing Director & Chief Executive Officer
Other key management personnel
Position
Dr Jolanta Airey
Chief Medical Officer
Dr Mathias Kroll
Chief Business Officer
The above-named persons held their current position for the whole of the financial year and since the end of the 
financial year.

26
Cynata Therapeutics Annual Report 2024/2025
26
Remuneration Report (cont’d)
2. 	Remuneration policy
Cynata’s remuneration policy was developed by 
the Board and has been designed to facilitate the 
alignment of shareholder, director and executive 
interests by:
	
z
Providing levels of fixed remuneration and ‘at 
risk’ remuneration sufficient to attract and retain 
individuals with the skills and experience required 
to build on and execute the Company’s business 
strategy.
	
z
Ensuring ‘at risk’ remuneration is contingent on 
outcomes that grow shareholder value.
	
z
Ensuring a suitable proportion of remuneration 
is received as a share-based payment so that 
rewards are realised through the performance of 
the Company over the longer term.
Remuneration consists of:
	
z
Fixed remuneration
	
z
Short-term incentives (‘STI’)
	
z
Long-term incentives (‘LTI’)
	
z
Benefits (e.g., car parking, telephone, etc.)
The fixed remuneration component is determined 
regarding market conditions, so that the Company can 
recruit and retain the best available talent.
The Board’s policy regarding short- and long-term 
incentives includes cash bonuses (STI) and the 
granting of options under the Company’s Employee 
Option Acquisition Plan (EOAP) (LTI).  Options are 
granted with an exercise price at a premium to the 
underlying market value of shares at the time of 
grant and vest over time subject to continuity of 
employment.  The term of options is set to ensure that 
there is a reasonable expectation that the strategies 
and actions of the recipients will, if successful, 
produce above-market Company performance.  This 
policy aligns the interests of executives with those 
of shareholders and creates a direct relationship 
between individual remuneration outcomes and 
Company performance.
As at the date of this report, the Company has one 
executive – the Chief Executive Officer, four non-
executive directors, one Chief Medical Officer and 
one Chief Business Officer. As set out below, total 
remuneration costs for the 2025 financial year were 
$1,801,531 up from $1,446,293 for the previous 
financial year.
(a) Non-executive Director Remuneration
Non-executive directors are remunerated by way of 
fees, in the form of cash, superannuation contributions 
(if paid via the Company’s payroll), the award of 
options on appointment and during their tenure from 
time-to-time or salary sacrifice into equity (both 
of which are subject shareholder approval).  Fees 
(including the award of options) for non-executive 
directors are not linked to the performance of 
the Company.  To align directors’ interests with 
shareholder interests, the directors are encouraged to 
hold shares in the Company and do not participate in 
schemes designed for the remuneration of executives.
If paid via the Company’s payroll, non-executive 
directors receive a superannuation guarantee 
contribution required by the government, which was 
11.5% in the 2024/2025 financial year and do not 
receive any other retirement benefits.  Individuals 
may choose to sacrifice part of their fees to increase 
payments towards superannuation.
The Board’s policy is to remunerate non-executive 
directors at market rates for comparable companies 
for time, commitment and responsibilities.  The Board 
determines, subject to a fee pool as approved by 
shareholders, payments to non-executive directors 
and reviews their remuneration annually, based on 
market practice, duties and accountability.
(b) Executive Director Remuneration
Executive directors receive fixed remuneration, based 
upon performance, professional qualifications and 
experience and superannuation benefits and under 
certain circumstances, options and performance 
incentives.

27
Remuneration Report (audited)
27
Executive Remuneration Objectives
An appropriate balance 
of ‘fixed’ and ‘at-risk’ 
components.
Attract, motivate, and 
retain executive talent.
The creation of reward 
differentiation to drive 
performance and 
behaviours.
Shareholder value 
creation through EOAP.
Total Remuneration
Fixed Remuneration
Short-Term Incentives
Long-Term Incentives
Set based on relevant market 
relativities, performance, 
qualifications, experience, and 
location.
Set by reference to Company and 
individual stretch performance 
targets relevant to the specific 
executive position.
Realisation dependent upon total 
shareholder return.
Delivery
Base salary including 
superannuation.
Payable in cash following review 
of performance against Key 
Performance Indicators (KPIs) and 
subject to Board discretion.
Eligible executives may participate 
in the Company’s equity-based 
incentive scheme subject to Board 
discretion. Equity options are issued 
under the Company’s EOAP at a 
premium to the underlying market 
value of shares and typically vest 
over a 3-year period.
Strategic Intent
Generally guided by the median 
compared to relevant market-based 
data taking into consideration 
expertise and performance in roles.
Directed at achieving short-term 
KPIs. Fixed Remuneration plus 
STI to be positioned competitively 
when compared to groups of 
similar companies.
LTI is intended to align executive 
performance with the Company’s 
long-term strategy and 
shareholders’ interests.
Overall remuneration policies are subject to the 
discretion of the Board and can be changed to reflect 
competitive and business conditions where it is in the 
interests of the Company and shareholders to do so.
Executive remuneration and other terms of 
employment are reviewed annually by the Board with 
reference to the Company’s performance, individual 
executive performance, comparable information from 
industry sectors and other listed companies in similar 
industries and where required, expert advice.
The Board has not formally engaged the services of a 
remuneration consultant to provide recommendations 
when setting the specific remuneration received by 
directors or other key management personnel during 
the financial year ended 30 June 2025.

28
Cynata Therapeutics Annual Report 2024/2025
28
Performance Measurement
The performance of executives is measured against 
criteria agreed annually with each executive and 
is based upon the achievement of the strategic 
objectives to secure shareholder value.
All incentive bonuses must be linked to predetermined 
performance criteria.  Key performance indicators 
(KPIs) are set annually by the Board on the following 
basis:
	
z
are specifically tailored to the responsibility areas 
in which the executive is directly involved.
	
z
target areas that the Board believe hold greater 
potential for business expansion and shareholder 
value.
	
z
cover financial and non-financial as well as short 
and long-term goals.
	
z
represent stretch targets to encourage 
extraordinary performance.
KPIs for key management personnel are focused 
on the areas of operational excellence, investor/
stakeholder relations and corporate partnering and 
alliances.
Performance in relation to KPIs is assessed annually 
with incentives awarded depending on the number 
and difficulty of the KPIs achieved. Following 
this assessment, KPIs are reviewed by the Board 
considering their desired and actual outcomes and 
whether behaviours are reflective of responsible risk 
management and sustainable business practices. 
The efficacy of the KPIs is assessed in relation to the 
Company’s goals and shareholder wealth, before the 
KPIs are set for the following year.
The Board may, however, exercise its discretion in 
relation to approving incentives, bonuses, and options, 
and can decide on changes. Any change must be 
justified by reference to measurable performance 
criteria.
(c) Equity Settled Compensation
The fair value of the equity which executives and 
employees are granted is measured at grant date and 
recognised as an expense over the vesting period, with 
a corresponding increase to an equity account.  The 
fair value of shares is ascertained as the market bid 
price.  The fair value of options is ascertained using 
a Black–Scholes pricing model which incorporates all 
market vesting conditions.  The number of shares and 
options expected to vest is reviewed and adjusted at 
each reporting date such that the amount recognised 
for services received as consideration for the equity 
instruments granted shall be based on the number of 
equity instruments that eventually vest.
Remuneration Report (cont’d)

29
Remuneration Report (audited)
29
3.	 Relationship between the Remuneration Policy and 
Company Performance
The Board considers at this time, evaluation of 
the Group’s financial performance using generally 
accepted measures such as profitability, total 
shareholder return or per company comparison are 
either not relevant or difficult to objectively quantify as 
the Group is pre-revenue and at an early stage in the 
implementation of a commercialisation strategy that 
includes the development of a novel life sciences (i.e. 
therapeutic stem cell) technology and the identification 
and execution of business opportunities as outlined in 
the directors’ report.
The table below sets out summary information about 
the Group’s earnings and movements in shareholder 
wealth for the five (5) years to 30 June 2025:
30 June 2025
30 June 2024
30 June 2023
30 June 2022
30 June 2021
$
$
$
$
$
Other income
2,112,839
2,733,353
2,007,179
7,835,174
1,688,351
Net loss before tax
9,390,586
9,744,709
14,277,495
5,445,172
7,689,683
Net loss after tax
9,390,586
9,744,709
14,277,495
5,445,172
7,689,683
Share price at start of year
0.295
0.125
0.360
0.505
0.610
Share price at end of year
0.150
0.295
0.125
0.360
0.505
Basic/diluted loss per share (cents)
4.58
5.42
9.84
3.80
5.90

30
Cynata Therapeutics Annual Report 2024/2025
30
4.	 Remuneration of key management personnel
Short-term employee benefits
Post-
employment 
benefits
Share-based 
payment
Value of 
options as 
proportion of 
remuneration
Salary & 
fees
Cash 
bonus
Other
Super-
annuation
Options
Total
2025
$
$
$
$
$
$
%
Directors
G. Brooke
123,732
-
-
-
14,062
137,794
10.20%
K. Kelly 1
404,788
47,602
28,792
27,653
21,093
529,928
3.98%
P. Wotton
61,866
-
-
-
6,187
68,053
9.09%
D. Maher
55,485
-
-
6,381
6,187
68,053
9.09%
J. Rolfe
61,866
-
-
-
19,677
81,543
24.13%
Other KMP
J. Airey 2
311,912
24,955
13,526
29,932
18,562
398,887
4.65%
M. Kroll 3
320,068
31,938
11,133
27,438
126,696
517,273
24.49%
Total
1,339,717
104,495
53,451
91,404
212,464
1,801,531
11.79%
1	
The amount of $47,602 under ‘Cash bonus’ represent 
potential bonus accrued for the financial year 2025.  
Amounts in ‘Other’ represent annual leave and long 
service leave accrued in accordance with AASB 119 
Employee Benefits. 
2	
The amount of $24,955 under ‘Cash bonus’ represent 
potential bonus accrued for the financial year 2025.  
Amounts in ‘Other’ represent annual leave accrued in 
accordance with AASB 119 Employee Benefits.
3	
The amount of $31,938 under ‘Cash bonus’ represent 
potential bonus accrued for the financial year 2025. 
Amounts in ‘Other’ represent annual leave accrued in 
accordance with AASB 119 Employee Benefits.
Remuneration Report (cont’d)

31
Remuneration Report (audited)
31
Short-term employee benefits
Post-
employment 
benefits
Share-based 
payment
Value of 
options as 
proportion of 
remuneration
Salary & 
fees
Cash 
bonus
Other
Super-
annuation
Options
Total
2024
$
$
$
$
$
$
%
Directors
G. Brooke
118,973
-
-
-
19,796
138,769
14.27%
K. Kelly1
390,601
67,716
29,417
27,399
29,694
544,827
5.45%
P. Wotton
59,487
-
-
-
8,710
68,197
12.77%
D. Maher
53,592
-
-
5,895
8,710
68,197
12.77%
J. Rolfe
59,487
-
-
-
22,200
81,687
27.18%
D. Atkins2
21,977
-
-
-
-
21,977
-
Other KMP
J. Airey3
299,915
13,496
21,006
27,399
36,908
398,724
9.26%
M. Kroll4
65,987
-
4,982
6,850
46,096
123,915
37.20%
Total
1,070,019
81,212
55,405
67,543
172,114
1,446,293
11.90%
1	
The amount of $67,716 under ‘Cash bonus’ represents 
potential bonus accrued for the financial year 2024.  
Amounts in ‘Other’ represent annual leave and long 
service leave accrued in accordance with AASB 119 
Employee Benefits. 
2	
Appointed 1 July 2023, resigned 13 November 2023.
3	
The amount of $13,496 under ‘Cash bonus’ represents 
potential bonus accrued for the financial year 2024.  
Amounts in ‘Other’ represent annual leave accrued in 
accordance with AASB 119 Employee Benefits.
4	
Appointed Chief Business Officer on 17 April 2023. 
Amounts in ‘Other’ represent annual leave accrued in 
accordance with AASB 119 Employee Benefits.

32
Cynata Therapeutics Annual Report 2024/2025
32
(a) Bonuses and share-based payments granted as 
compensation for the current financial year
(i) Bonuses
An STI payable as cash of $67,716 to Dr Kelly 
and $13,496 to Dr Airey was accrued in the 2024 
accounts. These were paid in August 2024.  A 
potential STI of $47,602 for Dr Kelly, $24,955 for 
Dr Airey and $31,938 for Dr Kroll were accrued in 
the 2025 accounts.  These amounts are payable 
subsequent to 30 June 2025.
Allocation of STIs is determined by attainment of 
short and medium term KPIs, which are considered to 
be important drivers of value and typical within the 
biotechnology industry for a company at Cynata’s 
stage of development.  In respect of financial year 
2025, the following assessment was made in respect 
of key management personnel KPIs:
KPI
Dr Kelly
Dr Airey
Dr Kroll
Patient enrolment in clinical trials
Partially met
Partially met
Partially met
Manufacturing and process development
Met
Met
Met
Regulatory affairs
Met
Met
Met
Finance
Partially met
Partially met
Partially met
Business development
Not met
Not met
Not met
Share price target
Not met
Not met
Not met
No other STIs were granted to key management personnel during 2025.
(ii) Employee share option plan
Cynata Therapeutics Limited operates an ownership-
based scheme for executives and senior employees 
of the Group.  In accordance with the provisions of 
the plan, as approved by shareholders at a previous 
annual general meeting, executives and senior 
employees may be granted options to purchase 
parcels of ordinary shares.
Each employee share option converts to one ordinary 
share of Cynata Therapeutics Limited on exercise.  
No amounts are paid or payable by the recipient 
on receipt of the option. The options carry neither 
rights to dividends nor voting rights.  Options may be 
exercised at any time from the date of vesting to the 
date of their expiry.
Remuneration Report (cont’d)

33
Remuneration Report (audited)
33
Terms and conditions of share-based payment arrangements affecting remuneration of key management 
personnel in the current financial year or future financial years:
Option 
series	
Number
Grant date
Expiry date
Exercise price
Grant date 
fair value
Vesting date
CYPAB1
4,400,000
24 Nov 2020
29 Nov 2025
$0.970
$0.493
Vested
CYPAD2
1,000,000
11 Oct 2021
11 Oct 2025
$0.890
$0.156
Various
CYPAR3
300,000
22 Nov 2022
23 Nov 2027
$0.510
$0.135
Various
CYPAS4
2,000,000
30 Jun 2023
30 Jun 2028
$0.176
$0.075
Various
CYPAE5
1,910,000
13 Nov 2023
20 Nov 2028
$0.185
$0.079
Various
CYPAF6
500,000
16 Jan 2024
16 Jan 2029
$0.195
$0.084
Various
CYPAT7
1,800,000
17 Apr 2024
17 Apr 2029
$0.290
$0.144
Various
1	
Unlisted options issued to Directors and former Directors 
pursuant to an Employee Option Acquisition Plan.
2	
Unlisted options issued to Dr Airey pursuant to an 
Employee Option Acquisition Plan.
3	
Unlisted options issued to Ms Rolfe pursuant to the 
terms of her appointment as non-executive director.
4	
Unlisted options issued to Dr Kelly pursuant to the terms 
of his appointment as Managing Director & CEO.
5	
Unlisted options issued to Directors pursuant to an 
Employee Option Acquisition Plan.
6	
Unlisted options issued to Dr Airey pursuant to an 
Employee Option Acquisition Plan.
7	
Unlisted options issued to Dr Kroll pursuant to an 
Employee Option Acquisition Plan.
There were no share-based payments granted as 
compensation to key management personnel during 
the current financial year (2024: 4,210,000 options).
No share options granted as part of their 
compensation were exercised by key management 
personnel during the year (2024: nil)
The following table summarises the number of options 
that lapsed during the financial year, in relation to 
options granted to key management personnel as part 
of their remuneration:
Name
Financial year in 
which the options 
were granted
No. of options 
lapsed during the 
current year
K. Kelly
2020
1,000,000

34
Cynata Therapeutics Annual Report 2024/2025
34
5. 	Key terms of employment contracts
The non-executive chair, Dr Geoff Brooke, was paid a 
fee of $123,732 (excluding GST) for the period 1 July 
2024 – 30 June 2025. Effective 1 July 2025, Dr Brooke 
will be a paid an annual fee of $128,063 (excluding 
GST).
The other non-executive directors, Dr Paul Wotton, 
Dr Darryl Maher and Ms Janine Rolfe were each paid a 
fee of $61,866 (including superannuation or excluding 
GST as the case may be) for the period 1 July 2024 
– 30 June 2025. Effective 1 July 2025, these non-
executive directors will be paid an annual fee of 
$64,031 (including superannuation or excluding GST 
as the case may be).
The award of options as part of the fees to all non-
executive directors are separately disclosed in this 
Report and are not linked to the performance of the 
Company.  It is not customary for non-executive 
directors to have notice periods. The appointment of 
any of the non-executive directors may be terminated 
if the director gives notice of resignation and the 
appointment may be terminated immediately if the 
director becomes disqualified or prohibited by law 
from being or acting as a director or from being 
involved in the management of a company.
The key terms of employment for the executive KMP 
are set out in the following table:
Employee
Remuneration / Fees*
Performance-based 
remuneration criteria 
Notice period
Dr Kilian Kelly
Effective 1 July 2025, a salary of 
$449,935 per annum including 
superannuation. For financial year 
2025, a salary of $434,720 per 
annum including superannuation.
An incentive payment of up to 30% 
of the annual salary and based on 
attainment of agreed KPIs.
The Company may (but is not bound 
to) pay additional performance-
based remuneration.
The contract may 
be terminated by 
either party providing 
3 months’ notice.
The Company may also 
terminate employment 
immediately and without 
further payment where 
the employee commits 
serious misconduct and 
on other similar grounds.
Any termination 
payments are paid 
within applicable 
legislative requirements.
Dr Jolanta Airey
Effective 1 Jul 2025, a salary of 
$352,829 per annum inclusive of 
statutory superannuation.  Dr Airey 
is employed on a part-time (0.8 
FTE) basis.
 An incentive payment of up to 20% 
of the annual salary and based on 
attainment of agreed KPIs.
Dr Mathias Kroll
Effective 1 July 2025, a salary of 
$362,250 per annum including 
superannuation.
An incentive payment of up to 25% 
of the annual salary and based on 
attainment of agreed KPIs.
* In addition, all KMP are eligible to, and have participated, in the Company’s equity-based incentive scheme. The award of 
options under this scheme to KMP are separately disclosed in this Report.
Remuneration Report (cont’d)

35
Remuneration Report (audited)
35
6.	 Key management personnel equity holdings
Fully paid ordinary shares of Cynata Therapeutics Limited
Balance at 
1 July 2024
Received on 
exercise of 
options
Shares 
acquired
Shares 
disposed
Balance at 
resignation
Balance at 
30 June 2025
2025
No.
No.
No. 1
No.
No.
No.
G. Brooke
257,343
-
55,555
-
-
312,898
K. Kelly
619,651
-
177,777
-
-
797,428
P. Wotton
315,309
69,767
200,000
-
-
585,076
D. Maher
50,000
-
66,666
-
-
116,666
J. Rolfe
116,279
-
138,888
-
-
255,167
J. Airey
-
-
-
-
-
-
M. Kroll
-
-
-
-
-
-
1	
Represents shares acquired pursuant to participation in 
a Placement.
Balance at 
1 July 2023
Received on 
exercise of 
options
Shares 
acquired
Shares 
disposed
Balance at 
resignation
Balance at
30 June 2024
2024
No.
No.
No.
No.
No.
No.
G. Brooke
257,343
-
-
-
-
257,343
K. Kelly
525,508
-
94,143
-
-
619,651
P. Wotton
315,309
-
-
-
-
315,309
D. Maher
50,000
-
-
-
-
50,000
J. Rolfe
116,279
-
-
-
-
116,279
J. Airey
-
-
-
-
-
-
M. Kroll 1
-
-
-
-
-
-
D. Atkins 2
-
-
-
-
-
-
S. Washer 3
2,364,390
-
-
-
(2,364,390)
-
1	
Appointed Chief Business Officer on 17 April 2024.
2	
Appointed 1 July 2023; resigned 13 Nov 2023.
3	
Resigned 1 July 2023.

36
Cynata Therapeutics Annual Report 2024/2025
36
Remuneration Report (cont’d)
Share options of Cynata Therapeutics Limited
Balance 
at 1 July 
2024
Granted
Lapsed
Exercised
Balance 
at 30 June 
2025
Balance 
vested at 
30 June 
2025
Vested and 
exercisable
Options 
vested 
during year
2025
No.
No.
No.
No.
No.
No.
No.
No.
G. Brooke
2,569,767
-
(69,767)
-
2,500,000
2,263,889
2,263,889
133,333
K. Kelly
3,765,748
-
(1,015,748)
-
2,750,000
1,729,153
1,729,153
713,405
P. Wotton
589,767
-
-
(69,767)
520,000
416,111
416,111
73,333
D. Maher
545,000
-
(25,000)
-
520,000
416,111
416,111
73,333
J. Rolfe
578,140
-
(58,140)
-
520,000
374,434
374,434
173,329
J. Airey
1,500,000
-
-
-
1,500,000
1,236,111
1,236,111
276,653
M. Kroll
1,800,000
-
-
-
1,800,000
583,333
583,333
500,000
Balance 
at 1 July 
2023
Granted
Lapsed
Exer-
cised
Balance on 
resignation
Balance 
at 30 June 
2024
Balance 
vested at 
30 June 
2024
Vested 
and 
exercis-
able
Options 
vested 
during 
year
2024
No.
No.
No.
No.
No.
No.
No.
No.
No.
G. Brooke
2,369,767
500,000
(300,000)
-
-
2,569,767
2,466,989
2,466,989
375,017
K. Kelly
3,015,748
750,000
-
-
3,765,748
1,828,241
1,828,241
840,271
P. Wotton
369,767
220,000
-
-
-
589,767
412,545
412,545
88,455
D. Maher
325,000
220,000
-
-
-
545,000
367,778
367,778
84,455
J. Rolfe
358,140
220,000
-
-
-
578,140
259,245
259,245
142,774
J. Airey
1,000,000
500,000
-
-
-
1,500,000
969,458
959,458
459,452
M. Kroll 1
-
1,800,000
-
-
-
1,800,000
83,333
83,333
83,333
D. Atkins 2
-
-
-
-
-
-
-
-
-
S. Washer 3
369,767
-
-
-
(369,767)
-
-
-
-
1	
Appointed Chief Business Officer on 17 April 2024.
2	
Appointed 1 July 2023; resigned 13 November 2023.
3	
Resigned 1 July 2023.



All share options issued to key management personnel 
were made in accordance with the provisions of the 
Employee Option Acquisition Plan.
Further details of the Employee Option Acquisition 
Plan and share options are contained in note 18 to the 
financial statements.

37
Remuneration Report (audited)
37
This is the end of the audited remuneration report
This directors’ report is signed in accordance with a 
resolution of directors made pursuant to s.298(2) of 
the Corporations Act 2001.
On behalf of the directors,
Dr Kilian Kelly
Managing Director & Chief Executive Officer
Melbourne,
28 August 2025

38
Cynata Therapeutics Annual Report 2024/2025
Auditor’s Independence 
Declaration
 
 
 
 
 
 
 
 
 
Liability limited by a scheme approved under Professional Standards Legislation  
 
 
PO Box 1908 
West Perth WA 6872 
Australia 
Level 2, 40 Kings Park Road 
West Perth WA 6005 
Australia 
Tel: +61 8 9481 3188 
Fax: +61 8 9321 1204 
ABN: 84 144 581 519 
www.stantons.com.au 
 
 
Stantons Is a member of the Russell 
Bedford International network of firms 
 
 
 
 
 
 
28 August 2025 
 
 
Board of Directors 
Cynata Therapeutics Limited 
Level 3, 100 Cubitt Street  
Cremorne, Victoria 3121 
 
 
Dear Directors  
 
 
RE: 
CYNATA THERAPEUTICS LIMITED 
 
In accordance with section 307C of the Corporations Act 2001, I am pleased to provide the following 
declaration of independence to the directors of Cynata Therapeutics Limited. 
 
As Audit Director for the audit of the financial statements of Cynata Therapeutics Limited for the year 
ended 30 June 2025, I declare that to the best of my knowledge and belief, there have been no 
contraventions of: 
 
(i) 
the auditor independence requirements of the Corporations Act 2001 in relation to the audit; and 
 
(ii) 
any applicable code of professional conduct in relation to the audit. 
 
Yours sincerely 
 
STANTONS INTERNATIONAL AUDIT AND CONSULTING PTY LTD 
 
Martin Michalik 
Director 
 
 
 
 
 
 
 
 

39
Independent Auditor’s Report
39
Independent Auditor’s Report
 
 
 
 
 
 
 
 
 
 
Liability limited by a scheme approved under Professional Standards Legislation  
 
 
PO Box 1908 
West Perth WA 6872 
Australia 
Level 2, 40 Kings Park Road 
West Perth WA 6005 
Australia 
Tel: +61 8 9481 3188 
Fax: +61 8 9321 1204 
ABN: 84 144 581 519 
www.stantons.com.au 
 
 
Stantons Is a member of the Russell 
Bedford International network of firms 
 
 
 
 
 
INDEPENDENT AUDITOR’S REPORT 
TO THE MEMBERS OF  
CYNATA THERAPEUTICS LIMITED 
 
Report on the Audit of the Financial Report  
 
Opinion 
 
We have audited the financial report of Cynata Therapeutics Limited (the Company) and its subsidiaries (collectively, 
the “Group”), which comprises the consolidated statement of financial position as at 30 June 2025, the consolidated 
statement of profit or loss and other comprehensive income, the consolidated statement of changes in equity and the 
consolidated statement of cash flows for the year then ended, and notes to the consolidated financial statements, 
including a summary of significant accounting policies, and the directors' declaration. 
 
In our opinion, the accompanying financial report of the Group is in accordance with the Corporations Act 2001, 
including: 
  
(i) 
giving a true and fair view of the Group’s financial position as at 30 June 2025 and of its financial performance 
for the year then ended; and 
 
(ii) 
complying with Australian Accounting Standards and the Corporations Regulations 2001. 
 
Basis for Opinion 
 
We conducted our audit in accordance with Australian Auditing Standards. Our responsibilities under those standards 
are further described in the Auditor's Responsibilities for the Audit of the Financial Report section of our report. We are 
independent of the Group in accordance with the auditor independence requirements of the Corporations Act 2001 
and the ethical requirements of the Accounting Professional and Ethical Standards Board's APES 110 Code of Ethics 
for Professional Accountants (the Code) that are relevant to our audit of the financial report in Australia. We have also 
fulfilled our other ethical responsibilities in accordance with the Code. 
 
We confirm that the independence declaration required by the Corporations Act 2001, which has been given to the 
directors of the Company, would be in the same terms if given to the directors as at the time of this auditor’s report. 
 
We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion. 
 
Material Uncertainty Related to Going Concern  
 
We draw attention to Note 3.1 to the financial statements, which indicates that the financial statements have been 
prepared on a going concern basis. At 30 June 2025 the Group had cash and cash equivalents totalling $5,049,744, 
cash outflow from operating activities of $8,720,335, and has incurred a loss before tax from continuing operations for 
the year of $9,390,586. These amounts indicate that a material uncertainty exists that may cast significant doubt on 
the Group’s ability to continue as a going concern. The Group’s ability to continue operations is dependent upon 
directors raising additional funding either through the issue of equity or debt or through the sale of assets, entering into 
corporate partnerships and by curtailing discretionary research and development spending. 
 
Our opinion is not modified in respect of this matter. 
 
 
 
 

40
Cynata Therapeutics Annual Report 2024/2025
40
Independent Auditor’s Report (cont’d)
  
 
 
 
 
 
 
Key Audit Matters 
 
Key audit matters are those matters that, in our professional judgement, were of most significance in our audit of the 
financial report of the current period. These matters were addressed in the context of our audit of the financial report 
as a whole, and in forming our opinion thereon, and we do not provide a separate opinion on these matters. In addition 
to the matter described in the Material Uncertainty Related to Going Concern section, we have determined the matters 
described below to be Key Audit Matters to be communicated in our report. 
 
 
Key Audit Matter 
How the matter was addressed in the audit 
 
Carrying value of intangible assets, amortisation 
and impairment 
 
At 30 June 2025, the carrying amount of the Group’s 
Intangible assets (patents) amounted to $1,848,904 
(2024: $1,851,868) as disclosed in Note 12 to the 
consolidated financial statements.  
 
Intangible assets are considered a key audit matter as 
they represent 31% of the net assets of the Group and 
require a level of judgement from management in 
assessing their recoverable amounts. 
 
 
 
 
 
 
 
 
Our audit procedures included, inter alia, the 
following: 
 
i. 
Reviewed ASX announcements and minutes of 
the Board of Directors meetings to obtain an 
understanding 
of 
the 
significant 
activities 
undertaken by the Group during the year; 
 
ii. Checked the validity of title to patents and 
ensured that any patents that have expired are 
written off;  
 
iii. Reviewed management’s assessment of the 
carrying value of the patents and assessed the 
appropriateness and relevance of the information 
provided to justify the carrying value of the 
patents;  
 
iv. Checked the amortisation charge to ensure that 
the patents are being amortised over the 20-year 
patents’ life; and 
 
v. Evaluated the adequacy of the disclosures in the 
consolidated financial assets.  
 
Key Audit Matters 
How the matters were addressed in the audit 
 
Measurement of Share-based Payments 
 
The Group had recorded a number of share-based 
payment transactions for the financial year ended 30 
June 2025, including the issue of a total of 6,000,000 
unlisted options to lead brokers and a further 
1,000,000 unlisted options to an external consultant. 
 
During the financial year ended 30 June 2025, the 
Company recognised a share-based payment expense 
of $229,237.  
 
Measurement of share-based payments was a key audit 
matter due to the complex and judgmental estimates 
used in determining the fair value of the share-based 
payments. 
 
 
 
 
Inter alia, our audit procedures included the 
following: 
 
i. 
Reviewing the relevant agreements to obtain an 
understanding of the contractual nature and 
terms and conditions of the share-based 
payment arrangements;  
 
ii. Assessing the assumptions used in the Group’s 
valuation of share options being the share price 
of the underlying equity, interest rate, volatility, 
dividend yield, time to maturity (expected life) 
and grant date; 
 
iii. Assessing the allocation of the share-based 
payment expense over the relevant vesting 
period; and 
 
iv. Assessing the appropriateness of the disclosures 
in Note 18 to the consolidated financial 
statements.  
 
 
 
 
 

41
Auditor’s Independence Declaration
41
Independent Auditor’s Report (cont’d)
  
 
 
 
 
 
 
 
Other Information 
 
The directors are responsible for the other information. The other information comprises the information included in 
the Group's annual report for the year ended 30 June 2025 but does not include the financial report and our auditor's 
report thereon. 
 
Our opinion on the financial report does not cover the other information and accordingly we do not express any form 
of assurance conclusion thereon. 
 
In connection with our audit of the financial report, our responsibility is to read the other information and, in doing so, 
consider whether the other information is materially inconsistent with the financial report or our knowledge obtained in 
the audit or otherwise appears to be materially misstated.  
 
If, based on the work we have performed, we conclude that there is a material misstatement of this other information, 
we are required to report that fact. We have nothing to report in this regard. 
 
Responsibilities of the Directors for the Financial Report 
 
The directors of the Company are responsible for the preparation of:  
 
a) 
the financial report that gives a true and fair view in accordance with Australian Accounting Standards and 
the Corporations Act 2001 (other than the consolidated entity disclosure statement); and  
 
b) 
the consolidated entity disclosure statement that is true and correct in accordance with the Corporations Act 
2001, and for such internal control as the directors determine is necessary to enable the preparation of: 
 
i) 
the financial report that gives a true and fair view and is free from material misstatement, whether 
due to fraud or error; and 
 
ii) 
the consolidated entity disclosure statement that is true and correct and is free from misstatement 
whether due to fraud and error. 
 
In preparing the financial report, the directors are responsible for assessing the ability of the Group to continue as a 
going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of 
accounting unless the directors either intend to liquidate the Group or to cease operations, or has no realistic alternative 
but to do so. 
 
Auditor's Responsibilities for the Audit of the Financial Report 
 
Our objectives are to obtain reasonable assurance about whether the financial report as a whole is free from material 
misstatement, whether due to fraud or error, and to issue an auditor's report that includes our opinion. Reasonable 
assurance is a high level of assurance, but is not a guarantee that an audit conducted in accordance with the Australian 
Auditing Standards will always detect a material misstatement when it exists. Misstatements can arise from fraud or 
error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence 
the economic decisions of users taken on the basis of this financial report. 
 
As part of an audit in accordance with Australian Auditing Standards, we exercise professional judgement and maintain 
professional scepticism throughout the audit. An audit involves performing procedures to obtain audit evidence about 
the amounts and disclosures in the financial report. 
 
The procedures selected depend on the auditor's judgement, including the assessment of the risks of material 
misstatement of the financial report, whether due to fraud or error. In making those risk assessments, the auditor 
considers internal control relevant to the entity's preparation of the financial report that gives a true and fair view in 
order to design audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an 
opinion on the effectiveness of the entity's internal control. 
 
The risk of not detecting a material misstatement resulting from fraud is higher than for one resulting from error, as 
fraud may involve collusion, forgery, intentional omissions, misrepresentations, or the override of internal control. 
 
An audit also includes evaluating the appropriateness of accounting policies used and the reasonableness of 
accounting estimates made by the Directors, as well as evaluating the overall presentation of the financial report. 
 
We conclude on the appropriateness of the Directors' use of the going concern basis of accounting and, based on the 
audit evidence obtained, whether a material uncertainty exists related to events or conditions that may cast significant 
doubt on the Group’s ability to continue as a going concern. If we conclude that a material uncertainty exists, we are 

42
Cynata Therapeutics Annual Report 2024/2025
42
Auditor’s Independence Declaration (cont’d)
  
 
 
 
 
 
 
required to draw attention in our auditor's report to the related disclosures in the financial report or, if such disclosures 
are inadequate, to modify our opinion. Our conclusions are based on the audit evidence obtained up to the date of our 
auditor’s report. However, future events or conditions may cause the Group to cease to continue as a going concern. 
 
We evaluate the overall presentation, structure and content of the financial report, including the disclosures, and 
whether the financial report represents the underlying transactions and events in a manner that achieves fair 
presentation. 
 
We obtain sufficient appropriate audit evidence regarding the financial information of the entities or business activities 
within the Group to express an opinion on the financial report. We are responsible for the direction, supervision and 
performance of the Group audit. We remain solely responsible for our audit opinion. 
 
We communicate with the Directors regarding, among other matters, the planned scope and timing of the audit and 
significant audit findings, including any significant deficiencies in Internal control that we identify during our audit. 
 
The Auditing Standards require that we comply with relevant ethical requirements relating to audit engagements. We 
also provide the Directors with a statement that we have complied with relevant ethical requirements regarding 
independence, and to communicate with them all relationships and other matters that may reasonably be thought to 
bear on our independence, and where applicable, related safeguards. 
 
From the matters communicated with the Directors, we determine those matters that were of most significance in the 
audit of the financial report of the current period and are therefore key audit matters. We describe these matters in our 
auditor's report unless law or regulation precludes public disclosure about the matter or when, in extremely rare 
circumstances, we determine that a matter should not be communicated in our report because the adverse 
consequences of doing so would reasonably be expected to outweigh the public interest benefits of such 
communication. 
 
Report on the Remuneration Report  
 
Opinion on the Remuneration Report  
 
We have audited the Remuneration Report included on pages 24 to 36 in the directors’ report for the year ended 30 
June 2025.  
 
In our opinion, the Remuneration Report of Cynata Therapeutics Limited for the year ended 30 June 2025 complies 
with section 300A of the Corporations Act 2001. 
 
Responsibilities 
 
The directors of the Company are responsible for the preparation and presentation of the Remuneration Report in 
accordance with section 300A of the Corporations Act 2001. Our responsibility is to express an opinion on the 
Remuneration Report, based on our audit conducted in accordance with Australian Auditing Standards. 
 
STANTONS INTERNATIONAL AUDIT AND CONSULTING PTY LTD 
(An Authorised Audit Company) 
 
Martin Michalik  
Director 
 
West Perth, Western Australia 
28 August 2025 

43
Directors’ Declaration
43
The directors declare that:
(a)	 in the directors’ opinion, there are reasonable 
grounds to believe that the Group will be able to 
pay its debts as and when they become due and 
payable;
(b)	 in the directors’ opinion, the attached financial 
statements are in compliance with International 
Financial Reporting Standards, as stated in note 1 
to the financial statements;
(c)	 in the directors’ opinion, the attached financial 
statements and notes thereto are in accordance 
with the Corporations Act 2001, including 
compliance with accounting standards and giving 
a true and fair view of the financial position and 
performance of the Group; and
(d)	 the directors have been given the declarations 
required by s.295A of the Corporations Act 2001; 
and
(e)	 the information contained in the consolidated 
entity disclosure statement is true and correct.
Signed in accordance with a resolution of the directors 
made pursuant to s.295(5) of the Corporations Act 
2001.
On behalf of the directors,
Dr Kilian Kelly
Managing Director & Chief Executive Officer
Melbourne, 
28 August 2025
Directors’ Declaration

46
Cynata Therapeutics Annual Report 2024/2025
Financial Statements

47
Financial Statements
47
Consolidated statement of profit or loss
and other comprehensive income
for the year ended 30 June 2025
	
	
Year ended
30 June 2025
30 June 2024
Note
$
$
Interest income
6
227,699
417,710
Other income
6
1,885,140
2,315,643
Total revenue and other income
2,112,839
2,733,353
Product development costs
7
(7,398,004)
(8,681,364)
Employee benefits expenses
8
(2,067,760)
(1,933,007)
Amortisation expenses
12
(282,964)
(280,732)
Share based payment expenses
8,18
(260,415)
(228,463)
Other expenses
8
(1,494,282)
(1,354,496)
(Loss) before income tax
(9,390,586)
(9,744,709)
Income tax expense
9
-
-
(Loss) for the year
(9,390,586)
(9,744,709)
Other comprehensive income, net of income tax
Items that will not be reclassified subsequently to profit or loss
-
-
Items that may be reclassified subsequently to profit or loss
Exchange differences on translating foreign operations
-
-
Other comprehensive income for the year, net of income tax
-
-
Total comprehensive loss for the year
(9,390,586)
(9,744,709)
(Loss) for the year attributable to:
Owners of Cynata Therapeutics Limited
(9,390,586)
(9,744,709)
Total comprehensive loss for the year attributable:
Owners of Cynata Therapeutics Limited
(9,390,586)
(9,744,709)
(Loss) per share:
Basic and diluted (cents per share)
10
(4.58)
(5.42)
The above consolidated statement of profit or loss and other comprehensive income should be read in 
conjunction with the accompanying notes.

48
Cynata Therapeutics Annual Report 2024/2025
48
Consolidated statement of financial position
as at 30 June 2025
30 June 2025
30 June 2024
Note
$
$
Current assets
Cash and cash equivalents
21
5,049,744
6,205,418
Trade and other receivables
11
104,650
113,184
Prepayments
194,618
217,820
Total current assets
5,349,012
6,536,422
Non-current assets
Intangibles
12
1,848,904
1,851,868
Total non-current assets
1,848,904
1,851,868
Total assets
7,197,916
8,388,290
Current liabilities
Trade and other payables
13
941,058
950,627
Provisions
14
275,123
220,428
Total current liabilities
1,216,181
1,171,055
Total liabilities
1,216,181
1,171,055
Net assets
5,981,735
7,217,235
Equity
Issued capital
15
89,519,207
81,624,596
Option reserves
16.1
8,166,905
7,906,430
Foreign currency translation reserve
16.2
4,724
4,724
Accumulated losses
(91,709,101)
(82,318,515)
Total equity
5,981,735
7,217,235
The above consolidated statement of financial position should be read in conjunction with the 
accompanying notes.

49
Financial Statements
49
Consolidated statement of changes in equity
for the year ended 30 June 2025
Issued 
Capital
Option 
Reserve
Foreign 
currency 
translation 
reserve
Accum-
ulated 
losses
Total
$
$
$
$
$
Balance at 1 July 2023
81,624,596
7,677,967
4,724
(72,573,806)
16,733,481
Loss for the year
-
-
-
(9,744,709)
(9,744,709)
Other comprehensive income for the year, net 
of tax
-
-
-
-
-
Total comprehensive income/(loss) for the year
-
-
-
(9,744,709)
(9,744,709)
Issue of ordinary shares (refer to note 15)
-
-
-
-
-
Share issue costs
-
-
-
-
-
Share based payments (refer to note 16.1)
-
228,463
-
-
228,463
Balance at 30 June 2024
81,624,596
7,906,430
4,724
(82,318,515)
7,217,235
$
$
$
$
$
Balance at 1 July 2024
81,624,596
7,906,430
4,724
(82,318,515)
7,217,235
Loss for the year
-
-
-
(9,390,586)
(9,390,586)
Other comprehensive income for the year, net 
of tax
-
-
-
-
-
Total comprehensive income/(loss) for the year
-
-
-
(9,390,586)
(9,390,586)
Issue of ordinary shares
8,416,875
-
-
-
8,416,875
Share issue costs
(522,264)
-
-
-
(522,264)
Share based payments (refer to note 16.1)
-
260,475
-
-
260,475
Balance at 30 June 2025
89,519,207
8,166,905
4,724
(91,709,101)
5,981,735
The above consolidated statement of changes in equity should be read in conjunction with the 
accompanying notes.


50
Cynata Therapeutics Annual Report 2024/2025
50
Consolidated statement of cash flows
for the year ended 30 June 2025
Year ended
30 June 2025
30 June 2024
Note
$
$
Cash flows from operating activities
Payments to suppliers and employees
(3,560,896)
(3,246,008)
Interest received
253,852
446,284
Research and development tax refund received
1,885,140
2,315,643
Other income (refund of office deposit)
-
21,960
Development costs paid
(7,298,431)
(9,498,440)
Net cash (used in) operating activities
21.1
(8,720,335)
(9,960,561)
Cash flows from investing activities
Payments to acquire intellectual property
(50,000)
-
Net cash (used in) investing activities
(50,000)
-
Cash flows from financing activities
Proceeds from issue of equity instruments of the Company
15
8,136,935
-
Payment for share issue costs
(522,264)
-
Net cash provided by financing activities
7,614,671
-
Net (decrease) in cash and cash equivalents
(1,155,664)
(9,960,561)
Cash and cash equivalents at the beginning of the year
6,205,418
16,167,356
Effects of exchange rate changes on the balance of cash held in foreign 
currencies
(10)
(1,377)
Cash and cash equivalents at the end of the year
21
5,049,744
6,205,418
The above consolidated statement of cash flows should be read in conjunction with the accompanying notes.

51
Financial Statements

52
Cynata Therapeutics Annual Report 2024/2025
52
1.	 General information
Statement of compliance
Cynata Therapeutics Limited (“the Company”) is a 
listed public company incorporated in Australia. The 
addresses of its registered office and principal place of 
business are disclosed in the corporate directory to the 
annual report.
The principal activities of the Company and its 
controlled subsidiaries (“the Group”) are described in 
the directors’ report.
These financial statements are general purpose 
financial statements which have been prepared 
in accordance with the Corporations Act 2001, 
Accounting Standards and Interpretations and comply 
with other requirements of the law.
The financial statements comprise the consolidated 
financial statements of the Group.  For the purposes of 
preparing the consolidated financial statements, the 
Company is a for-profit entity.
Accounting Standards include Australian Accounting 
Standards. Compliance with Australian Accounting 
Standards ensures that the financial statements and 
notes of the Company and the Group comply with 
International Financial Reporting Standards (‘IFRS’).
The financial statements were authorised for issue by 
the directors on 28 August 2025.
2.	 Application of new and revised 
Accounting Standards
2.1 	 Amendments to Accounting Standards and 
new Interpretations that are mandatorily 
effective for the current year
The Group has adopted all of the new and revised 
Standards and Interpretations issued by the 
Australian Accounting Standards Board (the AASB) 
that are relevant to its operations and effective for an 
accounting period that begins on or after 1 July 2024.
Any new or amended Accounting Standards or 
Interpretations that are not yet mandatory have not 
been early adopted.
3.	 Material accounting policy 
information
3.1	 Basis of preparation
The consolidated financial statements have been 
prepared on the basis of historical cost, except for 
certain financial instruments that are measured at 
revalued amounts or fair values at the end of each 
reporting period, as explained in the accounting 
policies below. Historical cost is generally based on 
the fair values of the consideration given in exchange 
for goods and services.  All amounts are presented in 
Australian dollars (“$”), unless otherwise noted.
Notes
Notes to the consolidated financial statements for the year 
ended 30 June 2025

53
Notes
53
Fair value is the price that would be received to sell 
an asset or paid to transfer a liability in an orderly 
transaction between market participants at the 
measurement date, regardless of whether that price 
is directly observable or estimated using another 
valuation technique. In estimating the fair value of 
an asset or liability, the Group takes into account 
the characteristics of the asset or liability at the 
measurement date. Fair value for measurement and/
or disclosure purposes in these consolidated financial 
statements is determined on such a basis, except for 
share-based payment transactions that are within 
the scope of AASB 2 Share-based Payment, leasing 
transactions that are within the scope of AASB 16 
Leases, and measurements that have some similarities 
to fair value but are not fair value, such as net 
realisable value in AASB 102 Inventories or value in 
use in AASB 136 Impairment of Assets.
In addition, for financial reporting purposes, fair value 
measurements are categorised into Level 1, 2 or 3 
based on the degree to which inputs to the fair value 
measurements are observable and the significance of 
the inputs to the fair value measurement in its entirety, 
which are described as follows:
	
z
Level 1 inputs are quoted prices (unadjusted) in 
active markets for identical assets or liabilities that 
the entity can access at the measurement date;
	
z
Level 2 inputs are inputs, other than quoted prices 
included in Level 1, that are observable for the 
asset or liability, either directly or indirectly; and
	
z
Level 3 inputs are unobservable inputs for the 
asset or liability.
Going concern
The financial report has been prepared on a going 
concern basis, which contemplates the continuity of 
normal business activity and the realisation of assets 
and the settlement of liabilities in the ordinary course 
of business.
As at 30 June 2025, the Group had net assets of 
$5,981,735 (2024: $7,217,235) and positive working 
capital of $4,132,831 (2024: $5,365,367) and in 
the year then ended incurred a loss after tax of 
$9,390,586 (2024: $9,744,709) and net operating cash 
outflows of $8,720,335 (2024: $9,960,561). As at 30 
June 2025, the Group had cash and cash equivalents 
of $5,049,744 (2024: $6,205,418).
As the Group continues to develop and commercialise 
its proprietary induced pluripotent stem cell (iPSC)-
based platform technology Cymerus™, the Group may 
require additional working capital that may be funded 
through cash flows from existing assets (e.g. corporate 
partnerships) and/or additional capital raisings. The 
directors consider the Group can manage its cash flow 
to ensure sufficient funds are available to meet its 
financial responsibilities. Based on this, the directors 
consider it appropriate that the financial report be 
prepared on a going concern basis.
In the event that the Group is unable to obtain 
sufficient funding for on-going operational and capital 
requirements, there is material uncertainty that may 
cast significant doubt as to whether the Group will 
continue as a going concern and therefore proceed 
with realising its assets and discharging its liabilities in 
the normal course of business at the amounts stated 
in the financial report. 
The ability of the Group to continue as a going concern 
and meet its operational and other commitments is 
dependent upon the Group developing its business, 
commercialising its iPSC-based platform technology, 
revenue growth and obtaining additional working 
capital that may be funded through cash flows from 
existing assets (e.g. corporate partnerships) and/ 
or additional capital raisings. The directors have 
reviewed the business outlook and cashflow forecasts 
and are the of opinion that the use of the going 
concern basis of accounting is appropriate as they 
believe the Group will continue to be successful in 
doing so. 
The consolidated financial statements do not include 
any adjustments relating to the recoverability or 
classification of recorded asset amounts or to the 
amounts or classification of liabilities that may be 
necessary should the Group not be able to continue as 
a going concern.

54
Cynata Therapeutics Annual Report 2024/2025
54
3.2	 Basis of consolidation
The consolidated financial statements incorporate 
the financial statements of the Company and entities 
controlled by the Company and its subsidiaries. 
Control is achieved when the Company:
	
z
has power over the investee;
	
z
is exposed, or has rights, to variable returns from 
its involvement with the investee; and
	
z
has the ability to use its power to affect its 
returns.
The Company reassesses whether or not it controls an 
investee if facts and circumstances indicate that there 
are changes to one or more of the three elements of 
control listed above.
Consolidation of a subsidiary begins when the 
Company obtains control over the subsidiary and 
ceases when the Company loses control of the 
subsidiary. Specifically, income and expenses of a 
subsidiary acquired or disposed of during the year 
are included in the consolidated statement of profit or 
loss and other comprehensive income from the date 
the Company gains control until the date when the 
Company ceases to control the subsidiary.
Profit or loss and each component of other 
comprehensive income are attributed to the owners 
of the Company and to the non-controlling interests.  
Total comprehensive income of subsidiaries is 
attributed to the owners of the Company and to the 
non-controlling interests even if this results in the non-
controlling interests having a deficit balance.
When necessary, adjustments are made to the 
financial statements of subsidiaries to bring their 
accounting policies into line with the Group’s 
accounting policies. All intragroup assets and 
liabilities, equity, income, expenses and cash flows 
relating to transactions between members of the 
Group are eliminated in full on consolidation.
3.3	 Business combinations
Acquisitions of businesses are accounted for using 
the acquisition method. The consideration transferred 
in a business combination is measured at fair value 
which is calculated as the sum of the acquisition-
date fair values of assets transferred by the Group, 
liabilities incurred by the Group to the former owners 
of the acquiree and the equity instruments issued by 
the Group in exchange for control of the acquiree. 
Acquisition-related costs are recognised in profit or 
loss as incurred.
At the acquisition date, the identifiable assets 
acquired and the liabilities assumed are recognised at 
their fair value, except that:
	
z
deferred tax assets or liabilities and assets 
or liabilities related to employee benefit 
arrangements are recognised and measured in 
accordance with AASB 112 Income Taxes and 
AASB 119 Employee Benefits respectively;
	
z
liabilities or equity instruments related to share-
based payment arrangements of the acquiree 
or share-based payment arrangements of the 
Group entered into to replace share-based 
payment arrangements of the acquiree are 
measured in accordance with AASB 2 Share-
based Payment at the acquisition date; and
	
z
assets (or disposal groups) that are classified as 
held for sale in accordance with AASB 5 Non-
current Assets Held for Sale and Discontinued 
Operations are measured in accordance with that 
Standard.
Goodwill is measured as the excess of the sum of the 
consideration transferred, the amount of any non-
controlling interests in the acquiree, and the fair value 
of the acquirer’s previously held equity interest in the 
acquiree (if any) over the net of the acquisition-date 
amounts of the identifiable assets acquired and the 
liabilities assumed. If, after reassessment, the net of 
the acquisition-date amounts of the identifiable assets 
acquired and liabilities assumed exceeds the sum 
of the consideration transferred, the amount of any 
non-controlling interests in the acquiree and the fair 
value of the acquirer’s previously held interest in the 
acquiree (if any), the excess is recognised immediately 
in profit or loss as a bargain purchase gain.
Non-controlling interests that are present ownership 
interests and entitle their holders to a proportionate 
share of the entity’s net assets in the event of 
Material accounting policy information (cont’d)

55
Notes
55
liquidation may be initially measured either at fair 
value or at the non-controlling interests’ proportionate 
share of the recognised amounts of the acquiree’s 
identifiable net assets. The choice of measurement 
basis is made on a transaction-by-transaction basis. 
Other types of non-controlling interests are measured 
at fair value or, when applicable, on the basis specified 
in another Standard.
Where the consideration transferred by the Group 
in a business combination includes assets or 
liabilities resulting from a contingent consideration 
arrangement, the contingent consideration is 
measured at its acquisition-date fair value. Changes 
in the fair value of the contingent consideration 
that qualify as measurement period adjustments 
are adjusted retrospectively, with corresponding 
adjustments against goodwill. Measurement 
period adjustments are adjustments that arise 
from additional information obtained during the 
‘measurement period’ (which cannot exceed one 
year from the acquisition date) about facts and 
circumstances that existed at the acquisition date.
The subsequent accounting for changes in the fair 
value of contingent consideration that do not qualify 
as measurement period adjustments depends on 
how the contingent consideration is classified. 
Contingent consideration that is classified as equity 
is not remeasured at subsequent reporting dates and 
its subsequent settlement is accounted for within 
equity.  Contingent consideration that is classified 
as an asset or liability is remeasured at subsequent 
reporting dates in accordance with AASB 9 Financial 
Instruments, or AASB 137 Provisions, Contingent 
Liabilities and Contingent Assets as appropriate, with 
the corresponding gain or loss being recognised in 
profit or loss.
Where a business combination is achieved in 
stages, the Group’s previously held equity interest 
in the acquiree is remeasured to its acquisition date 
fair value and the resulting gain or loss, if any, is 
recognised in profit or loss. Amounts arising from 
interests in the acquiree prior to the acquisition 
date that have previously been recognised in other 
comprehensive income are reclassified to profit or loss 
where such treatment would be appropriate if that 
interest were disposed of.
If the initial accounting for a business combination is 
incomplete by the end of the reporting period in which 
the combination occurs, the Group reports provisional 
amounts for the items for which the accounting is 
incomplete. Those provisional amounts are adjusted 
during the measurement period (see above), or 
additional assets or liabilities are recognised, to 
reflect new information obtained about facts and 
circumstances that existed as of the acquisition date 
that, if known, would have affected the amounts 
recognised as of that date.
3.4	 Goodwill
Goodwill arising on an acquisition of a business 
is carried at cost as established at the date of the 
acquisition of the business (see 3.3 above) less 
accumulated impairment losses, if any.
For the purposes of impairment testing, goodwill is 
allocated to each of the Groups’ cash-generating units 
(or groups of cash-generating units) that is expected 
to benefit from the synergies of the combination.
A cash-generating unit to which goodwill has been 
allocated is tested for impairment annually, or more 
frequently when there is an indication that the unit 
may be impaired.  If the recoverable amount of the 
cash-generating unit is less than its carrying amount, 
the impairment loss is allocated first to reduce the 
carrying amount of any goodwill allocated to the unit 
and then to the other assets of the unit pro rata based 
on the carrying amount of each asset in the unit.  Any 
impairment loss for goodwill is recognised directly 
in profit or loss.  An impairment loss recognised for 
goodwill is not reversed in subsequent periods. On 
disposal of the relevant cash-generating unit, the 
attributable amount of goodwill is included in the 
determination of the profit or loss on disposal.
3.5	 Revenue recognition
The Group has applied AASB 15 Revenue from 
Contracts with Customers using the cumulative 
effective method. The Group does not have any 
revenue from contracts with customers.

56
Cynata Therapeutics Annual Report 2024/2025
56
3.5.1	 Interest income
Interest income from a financial asset is recognised 
when it is probable that the economic benefits will 
flow to the Group and the amount of revenue can be 
measured reliably.  Interest income is accrued on a 
time basis, by reference to the principal outstanding 
and at the effective interest rate applicable, which 
is the rate that exactly discounts estimated future 
cash receipts though the expected life of the financial 
asset to that asset’s net carrying amount on initial 
recognition.
3.5.2 Other income
Other income is generally income earned from 
transactions outside the course of the Group’s ordinary 
activities.  Other income is recognised in profit or loss 
when received.
3.6	 Foreign currencies
The individual financial statements of each group 
entity are presented in the currency of the primary 
economic environment in which the entity operates 
(its functional currency).  For the purpose of the 
consolidated financial statements, the results and 
financial position of each group entity are expressed 
in Australian dollars (“$”), which is the functional 
currency of the Company and the presentation 
currency for the consolidated financial statements.
In preparing the financial statements of each 
individual group entity, transactions in currencies 
other than the entity’s functional currency (foreign 
currencies) are recognised at the rates of exchange 
prevailing at the dates of the transactions. At the end 
of each reporting period, monetary items denominated 
in foreign currencies are retranslated at the rates 
prevailing at that date. Non-monetary items carried at 
fair value that are denominated in foreign currencies 
are translated at the rates prevailing at the date when 
the fair value was determined. Non-monetary items 
that are measured in terms of historical cost in a 
foreign currency are not retranslated.
For the purpose of presenting these consolidated 
financial statements, the assets and liabilities 
of the Group’s foreign operations are translated 
into Australian dollars using the exchange rates 
prevailing at the end of the reporting period.  Income 
and expense items are translated at the average 
exchange rates for the period, unless exchange 
rates fluctuated significantly during that period, in 
which case the exchange rates at the dates of the 
transactions are used. Exchange differences arising, 
if any, are recognised in other comprehensive income 
and accumulated in equity (and attributed to non-
controlling interests as appropriate).
Goodwill and fair value adjustments to identifiable 
assets acquired and liabilities assumed through 
acquisition of a foreign operation are treated as assets 
and liabilities of the foreign operation and translated 
at the rate of exchange prevailing at the end of each 
reporting period.  Exchange differences arising are 
recognised in other comprehensive income.
3.7	 Government grants
Government grants are not recognised until there is 
reasonable assurance that the Group will comply with 
the conditions attaching to them and that the grants 
will be received.
Government grants are recognised in profit or loss on 
a systematic basis over the periods in which the Group 
recognises as expenses the related costs for which 
the grants are intended to compensate. Specifically, 
government grants whose primary condition is that 
the Group should purchase, construct or otherwise 
acquire non-current assets are recognised as 
deferred revenue in the consolidated statement of 
financial position and transferred to profit or loss on a 
systematic and rational basis over the useful lives of 
the related assets.
Government grants that are receivable as 
compensation for expenses or losses already incurred 
or for the purpose of giving immediate financial 
support to the Group with no future related costs are 
recognised in profit or loss in the period in which they 
become receivable.
Material accounting policy information (cont’d)

57
Notes
57
3.8	 Employee benefits
Short-term and long-term employee benefits
A liability is recognised for benefits accrued to 
employees in respect of wages and salaries and 
annual leave when it is probable that settlement will 
be required and they are capable of being measured 
reliably.
Liabilities recognised in respect of short-term 
employee benefits are measured at their nominal 
values using the remuneration rate expected to apply 
at the time of settlement.
Liabilities recognised in respect of long-term employee 
benefits are measured as the present value of the 
estimated future cash outflows to be made by the 
Group in respect of services provided by employees up 
to reporting date.
3.9	 Share-based payment arrangements
Equity-settled share-based payments to employees 
and others providing similar services are measured at 
the fair value of the equity instruments at the grant 
date. Details regarding the determination of the fair 
value of equity-settled share-based transactions are 
set out in note 18.
The fair value determined at the grant date of the 
equity-settled share-based payments is expensed on 
a straight-line basis over the vesting period, based 
on the Group’s estimate of equity instruments that 
will eventually vest, with a corresponding increase 
in equity. At the end of each reporting period, the 
Group revises its estimate of the number of equity 
instruments expected to vest. The impact of the 
revision of the original estimates, if any, is recognised 
in profit or loss such that the cumulative expense 
reflects the revised estimate, with a corresponding 
adjustment to the equity-settled employee benefits 
reserve.
Equity-settled share-based payment transactions with 
parties other than employees are measured at the fair 
value of the goods or services received, except where 
that fair value cannot be estimated reliably, in which 
case they are measured at the fair value of the equity 
instruments granted, measured at the date the entity 
obtains the goods or the counterparty renders the 
service.
For cash-settled share-based payments, liability 
is recognised for the goods or services acquired, 
measured initially at the fair value of the liability. At 
the end of each reporting period until the liability is 
settled, and at the date of settlement, the fair value 
of the liability is remeasured, with any changes in fair 
value recognised in profit or loss for the year.
3.10	Taxation
Income tax expense represents the sum of the tax 
currently payable and deferred tax.
3.10.1	Current tax
The tax currently payable is based on taxable profit for 
the year. Taxable profit differs from profit before tax as 
reported in the consolidated statement of profit or loss 
and other comprehensive income because of items 
of income or expense that are taxable or deductible 
in other years and items that are never taxable or 
deductible. The Group’s current tax is calculated using 
the tax rates that have been enacted or substantively 
enacted by the end of the reporting period.
R&D rebates are accounted for on a cash basis and 
included under other income.
3.10.2	Deferred tax
Deferred tax is recognised on temporary differences 
between the carrying amounts of assets and liabilities 
in the consolidated financial statements and the 
corresponding tax bases used in the computation of 
taxable profit. Deferred tax liabilities are generally 
recognised for all taxable temporary differences. 
Deferred tax assets are generally recognised for all 
deductible temporary differences to the extent that 
it is probable that taxable profits will be available 
against which those deductible temporary differences 
can be utilised. Such deferred tax assets and liabilities 
are not recognised if the temporary difference arises 
from the initial recognition (other than in a business 
combination) of assets and liabilities in a transaction 
that affects neither the taxable profit nor the 

58
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58
accounting profit.  In addition, deferred tax liabilities 
are not recognised if the temporary difference arises 
from the initial recognition of goodwill.
Deferred tax liabilities are recognised for taxable 
temporary differences associated with investments 
in subsidiaries and associates, and interests in joint 
ventures, except where the Group is able to control the 
reversal of the temporary difference and it is probable 
that the temporary difference will not reverse in the 
foreseeable future. Deferred tax assets arising from 
deductible temporary differences associated with such 
investments and interests are only recognised to the 
extent that it is probable that there will be sufficient 
taxable profits against which to utilise the benefits of 
the temporary differences and they are expected to 
reverse in the foreseeable future.
The carrying amount of deferred tax assets is 
reviewed at the end of each reporting period and 
reduced to the extent that it is no longer probable that 
sufficient taxable profits will be available to allow all 
or part of the asset to be recovered.
Deferred tax assets and liabilities are measured at 
the tax rates that are expected to apply in the period 
in which the liability is settled or the asset realised, 
based on tax rates (and tax laws) that have been 
enacted or substantively enacted by the end of the 
reporting period.  The measurement of deferred tax 
liabilities and assets reflects the tax consequences 
that would follow from the manner in which the 
Group expects, at the end of the reporting period, to 
recover or settle the carrying amount of its assets and 
liabilities.
Deferred tax liabilities and assets are offset when 
there is a legally enforceable right to set off current 
tax assets against current tax liabilities and when they 
relate to income taxes levied by the same authority 
and the Group intends to settle its current tax assets 
and liabilities on a net basis.
3.10.3	Current and deferred tax for the year
Current and deferred tax are recognised in profit 
or loss, except when they relate to items that are 
recognised in other comprehensive income or directly 
in equity, in which case the current and deferred tax 
are also recognised in other comprehensive income 
or directly in equity, respectively. Where current tax 
or deferred tax arises from the initial accounting for a 
business combination, the tax effect is included in the 
accounting for the business combination.
3.11	Intangible assets
3.11.1	Intangible assets acquired in a business 
combination
Intangible assets acquired in a business combination 
and recognised separately from goodwill are initially 
recognised at their fair value at the acquisition date 
(which is regarded as their cost).
Intangibles have been identified as all granted patents 
and patent applications. They have a finite useful life 
and are carried at cost less accumulated amortisation. 
Amortisation is calculated using the straight-line 
method over the expected life of the assets, which is 
no more than 20 years.
3.11.2	Intangible assets acquired separately
Intangible assets with finite useful lives that 
are acquired separately are carried at cost less 
accumulated amortisation and accumulated 
impairment losses. Amortisation is recognised on a 
straight-line basis over their estimated useful lives 
which is no more than 20 years.  The estimated 
useful life and amortisation method are reviewed at 
the end of each reporting period, with the effect of 
any changes in estimate being accounted for on a 
prospective basis.
3.11.3	Derecognition of intangible assets
An intangible asset is derecognised on disposal, 
or when no future economic benefits are expected 
from use or disposal. Gains or losses arising from 
derecognition of an intangible asset, measured as the 
difference between the net disposal proceeds and the 
carrying amount of the asset are recognised in profit 
or loss when the asset is derecognised.
Material accounting policy information (cont’d)

59
Notes
59
3.12	Impairment of tangible and intangible assets 
other than goodwill
At the end of each reporting period, the Group reviews 
the carrying amounts of its tangible and intangible 
assets to determine whether there is any indication 
that those assets have suffered an impairment loss.  If 
any such indication exists, the recoverable amount of 
the asset is estimated in order to determine the extent 
of the impairment loss (if any). When it is not possible 
to estimate the recoverable amount of an individual 
asset, the Group estimates the recoverable amount of 
the cash-generating unit to which the asset belongs. 
When a reasonable and consistent basis of allocation 
can be identified, corporate assets are also allocated 
to individual cash-generating units, or otherwise they 
are allocated to the smallest group of cash-generating 
units for which a reasonable and consistent allocation 
basis can be identified.
Intangible assets with indefinite useful lives and 
intangible assets not yet available for use are tested 
for impairment at least annually, and whenever there 
is an indication that the asset may be impaired.
Recoverable amount is the higher of fair values less 
costs to sell and value in use.  In assessing value in 
use, the estimated future cash flows are discounted to 
their present value using a pre-tax discount rate that 
reflects current market assessments of the time value 
of money and the risks specific to the asset for which 
the estimates of future cash flows have not been 
adjusted.
If the recoverable amount of an asset (or cash-
generating unit) is estimated to be less than its 
carrying amount, the carrying amount of the 
asset (or cash-generating unit) is reduced to its 
recoverable amount.  An impairment loss is recognised 
immediately in profit or loss, unless the relevant asset 
is carried at a revalued amount, in which case the 
impairment loss is treated as a revaluation decrease.
When an impairment loss subsequently reverses, the 
carrying amount of the asset (or cash-generating unit) 
is increased to the revised estimate of its recoverable 
amount, but so that the increased carrying amount 
does not exceed the carrying amount that would 
have been determined had no impairment loss been 
recognised for the asset (or cash-generating unit) 
in prior years. A reversal of an impairment loss is 
recognised immediately in profit or loss, unless the 
relevant asset is carried at a revalued amount, in 
which case the reversal of the impairment loss is 
treated as a revaluation increase.
3.13	Provisions
Provisions are recognised when the Group has a 
present obligation (legal or constructive) as a result 
of a past event, it is probable that the Group will 
be required to settle the obligation, and a reliable 
estimate can be made of the amount of the obligation.
The amount recognised as a provision is the best 
estimate of the consideration required to settle the 
present obligation at the end of the reporting period, 
taking into account the risks and uncertainties 
surrounding the obligation. When a provision is 
measured using the cash flows estimated to settle the 
present obligation, its carrying amount is the present 
value of those cash flows (where the effect of the time 
value of money is material).
When some or all of the economic benefits required to 
settle a provision are expected to be recovered from a 
third party, a receivable is recognised as an asset if it 
is virtually certain that reimbursement will be received 
and the amount of the receivable can be measured 
reliably.
3.14	Financial instruments
Recognition, initial measurement and derecognition
Financial assets and financial liabilities are recognised 
when the Group becomes a party to the contractual 
provisions of the financial instrument.  Financial 
instruments (except for trade receivables) are 
measured initially at fair value adjusted by transaction 
costs, except for those carried at ‘fair value through 
profit or loss’, in which case transaction costs are 
expensed to profit or loss.  Where available, quoted 
prices in an active market are used to determine the 
fair value. In other circumstances, valuation techniques 
are adopted. Subsequent measurement of financial 
assets and financial liabilities are described below.

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Trade receivables are initially measured at the 
transaction price if the receivables do not contain a 
significant financing component in accordance with 
AASB 15.
Financial assets are derecognised when the 
contractual rights to the cash flows from the 
financial asset expire, or when the financial asset 
and all substantial risks and rewards are transferred.  
A financial liability is derecognised when it is 
extinguished, discharged, cancelled or expired.
Classification and measurement
FINANCIAL ASSETS
Except for those trade receivables that do not contain 
a significant financing component and are measured 
at the transaction price in accordance with AASB 15, 
all financial assets are initially measured at fair value 
adjusted for transaction costs (where applicable).
For the purpose of subsequent measurement, financial 
assets other than those designated and effective as 
hedging instruments are classified into the following 
categories upon initial recognition:
	
z
amortised cost;
	
z
fair value through other comprehensive income 
(FVOCI); and
	
z
fair value through profit or loss (FVPL).
Classifications are determined by both:
	
z
the contractual cash flow characteristics of the 
financial assets; and
	
z
the Group’s business model for managing the 
financial asset.
Financial assets at amortised cost
Financial assets are measured at amortised cost if the 
assets meet with the following conditions (and are not 
designated as FVPL);
	
z
they are held within a business model whose 
objective is to hold the financial assets and 
collect its contractual cash flows; and
	
z
the contractual terms of the financial assets give 
rise to cash flows that are solely payments of 
principal and interest on the principal amount 
outstanding.
After initial recognition, these are measured at 
amortised cost using the effective interest method.  
Discounting is omitted where the effect of discounting 
is immaterial.  The Group’s cash and cash equivalents, 
trade and most other receivables fall into this category 
of financial instruments.
Financial assets at fair value through other 
comprehensive income (Equity instruments)
The Group measures debt instruments at fair value 
through OCI if both of the following conditions are met:
	
z
the contractual terms of the financial asset give 
rise on specified dates to cash flows that are 
solely payments of principal and interest on the 
principal amount outstanding; and
	
z
the financial asset is held within a business 
model with the objective of both holding to collect 
contractual cash flows and selling the financial 
asset.
For debt instruments at fair value through OCI, interest 
income, foreign exchange revaluation and impairment 
losses or reversals are recognised in the statement of 
profit or loss and computed in the same manner as 
for financial assets measured at amortised cost.  The 
remaining fair value changes are recognised in OCI.
Upon initial recognition, the Group can elect to 
classify irrevocably its equity investments as equity 
instruments designated at fair value through OCI 
when they meet the definition of equity under AASB 
132 Financial Instruments: Presentation and are not 
held for trading.
Financial assets at fair value through profit or loss 
(FVPL)
Financial assets at fair value through profit or loss 
include financial assets held for trading, financial 
assets designated upon initial recognition at fair value 
through profit or loss or financial assets mandatorily 
required to be measured at fair value.  Financial assets 
are classified as held for trading if they are acquired 
for the purpose of selling or repurchasing in the near 
term.
Material accounting policy information (cont’d)

61
Notes
61
FINANCIAL LIABILITIES
Financial liabilities
Financial liabilities are classified, at initial recognition, 
as financial liabilities at fair value through profit or 
loss, loans and borrowings, payables or as derivatives 
designated as hedging instruments in an effective 
hedge, as appropriate.
Financial liabilities are initially measured at fair value, 
and, where applicable, adjusted for transaction costs 
unless the Group designated a financial liability at fair 
value through profit or loss.
Subsequently, financial liabilities are measured at 
amortised cost using the effective interest method 
except for derivatives and financial liabilities 
designated at FVPL, which are carried subsequently 
at fair value with gains or losses recognised in profit 
or loss.
All interest-related charges and, if applicable, gains 
and losses arising on changes in fair value are 
recognised in profit or loss.
IMPAIRMENT
The Group assesses on a forward-looking basis 
the expected credit loss associated with its debt 
instruments carried at amortised cost and FVOCI.  The 
impairment methodology applied depends on whether 
there has been a significant increase in credit risk.  For 
trade receivables, the Group applies the simplified 
approach permitted by AASB 9, which requires 
expected lifetime losses to be recognised from initial 
recognition of the receivables.
3.15	Leases
The Group as a lessee
At inception of a contract, the Group assesses if the 
contract contains characteristics of or is a lease.  If 
there is a lease present, a right-of-use asset and a 
corresponding liability are recognised by the Group 
where the Group is a lessee.  However, all contracts 
that are classified as short-term leases (i.e., leases 
with a remaining lease term of 12 months or less) 
and leases of low-value assets are recognised as an 
operating expense on a straight-line basis over the 
term of the lease.
Initially, the lease liability is measured at the present 
value of the lease payments still to be paid at the 
commencement date.  The lease payments are 
discounted at the interest rate implicit in the lease.  If 
this rate cannot be readily determined, the Group uses 
incremental borrowing rate.
Lease payments included in the measurement of the 
lease liability are as follows:
	
z
fixed lease payments less any lease incentives;
	
z
variable lease payments that depend on the 
index of the rate, initially measured using the 
index or rate at the commencement date;
	
z
the amount expected to be payable by the lessee 
under residual value guarantees;
	
z
the exercise price of purchase options if the lessee 
if reasonably certain to exercise the options;
	
z
lease payments under extension profits, if the 
lessee is reasonably certain to exercise the 
options; and
	
z
payments of penalties for terminating the lease, 
if the lease term reflects the exercise of options to 
terminate the lease.
The right-of-use assets comprise the initial 
measurement of the corresponding lease liability, any 
lease payments made at or before the commencement 
date and initial direct costs.  The subsequent 
measurement of the right-of-use asset is at cost less 
accumulated depreciation and impairment losses.
Right-of-use assets are depreciated over the lease 
term or useful life of the underlying asset, whichever is 
the shortest.
Where a lease transfers ownership of the underlying 
asset or the costs of the right-of-use asset reflects 
that the Group anticipates exercising a purchase 
option, the specific asset is depreciated over the useful 
life of the underlying asset.
The Group does not currently have any leases that 
would require recognition of a right-of-use asset in the 
current reporting period.

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Cynata Therapeutics Annual Report 2024/2025
62
3.16 Comparative amounts
When current period balances have been classified 
differently within current period disclosures when 
compared to prior periods, comparative disclosures 
have been restated to ensure consistency of 
presentation between periods.
4.	 Critical accounting judgements 
and key sources of estimation 
uncertainty
In the application of the Group’s accounting policies, 
which are described in note 3, the directors of the 
Company are required to make judgements, estimates 
and assumptions about the carrying amounts of 
assets and liabilities that are not readily apparent 
from other sources.  The estimates and associated 
assumptions are based on historical experience and 
other factors that are considered to be relevant.  
Actual results may differ from these estimates.
The estimates and underlying assumptions are 
reviewed on an ongoing basis. Revisions to accounting 
estimates are recognised in the period on which the 
estimate is revised if the revision affects only that 
period, or in the period of the revision and future 
periods if the revision affects both current and future 
periods.
4.1	 Key sources of estimation uncertainty
4.1.1	 Recoverability of intangible assets acquired in 
a business combination and acquired separately
During the year, the directors reconsidered the 
recoverability of the Group’s intangible assets arising 
from the acquisition of Cynata Incorporated as well 
as the intellectual property rights acquired from 
TekCyte Limited in July 2024, which is included in the 
consolidated statement of financial position at 30 
June 2025 with a carrying value of $1,848,904 (2024: 
$1,851,868) after accounting for amortisation.
The directors have allocated the carrying value 
of the intangibles (before amortisation) to the 
different categories of the research based on their 
estimates.  The resulting allocation has given rise to 
an amortisation expense of $2,282,964 for the year 
ended 30 June 2025 (2024: $280,732).
The directors performed an assessment of impairment 
indicators and concluded that no impairment of the 
intangible assets is required for the year (2024: nil).
4.1.2 Share-based payment transactions
The Group accounts for all equity-settled share-
based payments based on the fair value of the 
award on grant date.  Under the fair value-based 
method, compensation cost attributable to options 
granted is measured at fair value at the grant date 
and amortised over the vesting period.  The amount 
recognised as an expense is adjusted to reflect any 
changes in the Group’s estimate of the options that 
will eventually vest and the effect of any non-market 
vesting conditions.
Share-based payment arrangements in which the 
Group receives good or services as consideration 
are measured at the fair value of the good or service 
received, unless that fair value cannot be reliably 
estimated.
5.	 Segment information
The Group operates in one business segment, namely 
the development and commercialisation of therapeutic 
products. For management purposes, the Group is 
organised into one main operating segment which 
involves the development and commercialisation 
of therapeutic products. All of the Group’s activities 
are interrelated and discrete financial information 
is reported to the Board (Chief Operating Decision 
Maker) as a single segment.
Accordingly, all significant operating decisions are 
based upon analysis of the Group as one segment. 
The financial results from this segment are equivalent 
to the financial statements of the Group as a whole.

63
Notes
63
6.	 Interest income and other income
2025
2024
Interest income
$
$
Interest income
227,699
417,710
2025
2024
Other income
$
$
R&D rebate
1,885,140
2,315,643
7.	 Product development costs
2025
2024
$
$
Research and development expenses
6,565,975
8,156,550
Consultants
362,913
354,742
Travel and accommodation expenses
284,002
119,091
License fees
137,774
23,398
Patent costs
47,340
27,583
7,398,004
8,681,364

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Cynata Therapeutics Annual Report 2024/2025
64
8.	 Loss for the year
2025
2024
$
$
Loss for the year has been arrived at after charging the following items of expenses:
Employee benefits expenses
    Wages and salaries
1,848,717
1,689,277
    Superannuation expenses
164,349
143,450
    Leave entitlements
54,694
100,280
Total employee benefits expenses (i)
2,067,760
1,933,007
Share-based payment expenses
260,415
228,463
Other expenses
    Share registry fees
43,370
26,741
    Directors’ fees
309,331
319,410
    Legal costs
329,043
336,438
    Investor/public relations
101,014
80,666
    Corporate advisors
42,600
15,000
    Other administrative expenses
661,521
643,991
    Effect of foreign exchange
7,403
(67,750)
Total other expenses
1,494,282
1,354,496
(i)	
Excludes amounts charged to product development costs.

65
Notes
65
9.	 Income taxes relating to continuing operations
9.1	 Income tax recognised in profit or loss
2025
2024
$
$
Current tax
-
-
Deferred tax
-
-
-
-
The income tax expense for the year can be reconciled to the accounting 
loss as follows:

2025
2024
$
$
Loss before tax from continuing operations
(9,390,586)
(9,744,709)
Income tax expense calculated at 25% (2024: 25%)
(2,347,646)
(2,436,177)
Tax effect of R&D rebate received
(471,285)
(578,911)
Effect of expenses that are not deductible in determining taxable income
1,972,966
2,189,948
Effect of unused tax losses not recognised as deferred tax assets
845,965
825,140
-
-
The tax rate used for the 2025 reconciliations above is the corporate tax rate of 25% (2024: 25%) payable by 
Australian corporate entities on taxable profits under Australian tax law.
9.2	 Income tax recognised directly in equity
2025
2024
$
$
Current tax
Share issue costs
-
-
Deferred tax
Arising on transactions with owners:
    Share issue costs deductible over 5 years
-
-
-
-

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Cynata Therapeutics Annual Report 2024/2025
66
9.3	 Unrecognised deferred tax assets in relation to:
2025
2024
$
$
Unused tax losses (revenue) for which no deferred tax assets
have been recognised (i)
13,601,065
11,537,359
Other
174,655
151,712
13,775,690
11,689,071
9.4	 Unrecognised deferred tax (liabilities) in relation to:
2025
2024
$
$
Intangibles
(462,226)
(462,967)
Other
(55,485)
(67,824)
(517,711)
(530,791)
Net deferred tax assets
13,257,979
11,158,280
(i)	
All unused tax losses were incurred by Australian 
entities.  The figure also includes unused carried 
forward tax losses of Cynata Australia Pty Ltd (“Cynata 
Australia”).  Cynata Australia is the wholly owned 
subsidiary of Cynata Inc and Cynata Inc is the wholly 
owned subsidiary of Cynata Therapeutics Limited.
This benefit for tax losses will only be obtained if 
the specific entity carrying forward the tax losses 
derives future assessable income of a nature and 
of an amount sufficient to enable the benefit from 
the deductions for the losses to be realised, and the 
Company complies with the conditions for deductibility 
imposed by tax legislation.
10.	Loss per share
2025
2024
¢ / share
¢ / share
Basic and diluted loss per share
(4.58)
(5.42)
10.1	Basic and diluted loss per share
The loss and weighted average number of ordinary shares used in the calculation of basic earnings per share are 
as follows:
2025
2024
$
$
Loss for the year attributable to owners of the Company
(9,390,586)
(9,744,709)
2025
2024
$
$
Weighted average number of ordinary shares for the purposes of calculating basic 
and diluted loss per share
204,950,877
179,631,786
Income taxes relating to continuing operations (cont’d)

67
Notes
67
11.	Trade and other receivables
2025
2024
$
$
Deposits made
3,568
3,568
Other receivables
101,082
109,616
104,650
113,184
At the reporting date, none of the receivables were past due/impaired. There are no expected credit losses.
12.	Intangibles
2025
2024
$
$
Carrying value at beginning of year (i)
1,851,868
2,132,600
Additions (ii)
280,000
-
Amortisation (iii)
(282,964)
(280,732)
Net book value of research and development at end of year
1,848,904
1,851,868
(i)	
The carrying value at beginning of year represents 
the fair value attributable to interests in research and 
development of stem cells is due to, and in recognition 
of, the successful development activities and data 
generated by Cynata Incorporated as at the acquisition 
date (1 December 2013), representing progress 
toward the eventual commercialisation of the relevant 
technology less accumulated amortisation.
(ii)	 On 31 July 2024, Cynata issued 916,335 fully paid 
ordinary shares at a price of $0.251 each for a value 
of $230,000 to acquire wound dressing technology 
developed by TekCyte Limited. This technology is a core 
component of Cynata’s Cymerus iPSC-derived MSC 
topical wound dressing product candidate, CYP-006TK.  
Cynata also paid $50,000 cash in addition to the issue of 
the shares, as a milestone payment in accordance with 
the licence agreement signed in July 2021.
(ii)	 An amortisation expense of $282,964 has been 
recognised in profit or loss (2024: $280,732). Refer 
to note 3.12 for more information on the Group’s 
accounting policy on intangibles and amortisation.

Cost
2025
2024
$
$
Balance at 1 July
4,821,799
4,821,799
Additions (refer to note 12 above)
280,000
-
Disposals
-
-
Balance at 30 June
5,101,799
4,821,799

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Cynata Therapeutics Annual Report 2024/2025
68
Accumulated amortisation
2025
2024
$
$
Balance at 1 July
2,969,931
2,689,199
Amortisation expense
282,964 
280,732
Balance at 30 June
3,252,895
2,969,931
13.	Trade and other payables
2025
2024
$
$
Trade payables
393,895
431,893
Accrued expenses
547,163
518,734
941,058
950,627
14.	Provisions
2025
2024
$
$
Provisions for employee entitlements
275,123
220,428
15.	Issued capital
2025
2024
$
$
225,954,369 fully paid ordinary shares (2024: 179,631,786)
89,519,207
81,624,596
Fully paid ordinary shares
30 June 2025
30 June 2024
No.
$
No.
$
Balance at beginning of year
179,631,786
81,624,596
179,631,786
81,624,596
Issue of shares (i)
3,150
945
-
-
Issue of shares (ii)
916,335
230,000
-
-
Issue of shares (iii)
125,000
25,000
-
-
Issue of shares (iv)
125,000
25,000
-
-
Placement (v)
44,444,445
8,000,000
-
-
Issue of shares (vi)
638,886
115,000
-
-
Issue of shares (vii)
69,767
20,930
-
-
Share issue costs
-
(522,264)
-
-
Balance at end of the year
225,954,369
89,519,207
179,631,786
81,624,596
Intangibles (cont’d)

69
Notes
69
(i)	
Exercise of listed 1 April 2025 options at $0.30 each on 
19 July 2024.
(ii)	 Issue of shares on 31 July 2024 pursuant to a Deed of 
Assignment of Intellectual Property Rights. Refer to note 
12 for more information.
(iii)	 Issue of shares on 2 September 2024 in consideration for 
the first instalment for the provision of investor relations 
services.
(iv)	 Issue of shares on 8 November 2024 in consideration for 
the first instalment for the provision of investor relations 
services.
(v)	 Issue of shares on 16 December 2024 pursuant to an 
Institutional Placement at $0.18 per share.
(vi)	 Issue of Director shares on 23 January 2025 pursuant to 
a participation of Directors in the Institutional Placement 
at $0.18 per share.
(vii)	 Exercise of listed 1 April 2025 options at $0.30 each on 
20 February 2025.
16.	Reserves
16.1	Share-based payments
2025
2024
$
$
Balance at beginning of year
7,906,430
7,677,967
Recognition of share-based payments (i)
260,415
228,463
Issue of unlisted options (ii)
60
-
Balance at end of year
8,166,905
7,906,430
(i)	
Total expenses arising from share-based payment 
transactions as a result of vesting of unlisted options 
to executives, employees and contractors recognised 
during the year ended 30 June 2025 was $260,415 
(2024: $228,463).
(ii)	 Cash received from the issue of 6,000,000 unlisted 
options at $0.00001 per option to the lead broker of 
the Institutional Placement pursuant to a Corporate 
Advisory Mandate.
Further information about share-based payments is set out in note 18.
16.2	Foreign currency translation reserve
2025
2024
$
$
Balance at beginning of year
4,724
4,724
Exchange differences arising on translating the foreign operations
-
-
Balance at end of year
4,724
4,724
Exchange differences relating to the translation 
of results and net assets of the Group’s foreign 
operations from their functional currencies to the 
Group’s presentation currency (i.e., Australian dollars) 
are recognised directly in other comprehensive income 
and accumulated in the foreign currency translation 
reserve.

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17.	Financial instruments
17.1	Capital management
The Group’s objective when managing capital is to 
safeguard its ability to continue as a going concern so 
that it can continue to provide returns for shareholders 
and benefits to other stakeholders and to maintain an 
optimal capital structure to reduce the cost of capital.  
In order to maintain or adjust the capital structure, the 
Group may adjust the amount of dividends paid, return 
capital to shareholders, issue new shares or sell assets 
to reduce debt.
Given the nature of the business, the Group monitors 
capital on the basis of current business operations and 
cash flow requirements. There were no changes in the 
Group’s approach to capital management during the 
year.
17.2	Categories of financial instruments
2025
2024
$
$
Financial assets
Cash and cash equivalents
5,049,744
6,205,418
Trade and other receivables
104,650
113,184
5,154,394
6,318,602
Financial liabilities
Trade and other payables
941,058
950,627
941,058
950,627
Net financial assets
4,213,336
5,367,975
The fair value of the above financial instruments approximates their carrying values.
17.3	Financial risk management objectives
In common with all other businesses, the Group is 
exposed to risks that arise from its use of financial 
instruments. This note describes the Group’s 
objectives, policies and processes for managing those 
risks and the methods used to measure them. Further 
quantitative information in respect of those risks is 
presented throughout these financial statements.
There have been no substantive changes in the 
Group’s exposure to financial instrument risks, its 
objectives, policies and processes for managing those 
risks or the methods used to measure them from 
previous periods unless otherwise stated in this note.
The board has overall responsibility for the 
determination of the Group’s risk management 
objectives and policies and, whilst retaining ultimate 
responsibility for them, it has delegated the authority 
for designing and operating processes that ensure 
the effective implementation of the objectives and 
policies to the Group’s finance function.  The Group’s 
risk management policies and objectives are therefore 
designed to minimise the potential impacts of these 
risks on the Group where such impacts may be 
material.  The board receives monthly financial reports 
through which it reviews the effectiveness of the 
processes put in place and the appropriateness of the 
objectives and policies it sets.  The overall objective of 
the board is to set policies that seek to reduce risk as 
far as possible without unduly affecting the Group’s 
competitiveness and flexibility.

71
Notes
71
17.4	Market risk
Market risk for the Group arises from the use of 
interest-bearing financial instruments. It is the risk 
that the fair value or future cash flows of a financial 
instrument will fluctuate because of changes in 
interest rate (see 17.5 below).
17.5	Interest rate risk management
Interest rate risk arises on cash and cash equivalents 
and receivables from related parties. The Group does 
not enter into any derivative instruments to mitigate 
this risk. As this is not considered a significant risk for 
the Group, no policies are in place to formally mitigate 
this risk.
Interest rate sensitivity analysis
The sensitivity analyses below have been determined 
based on the exposure to interest rates for both 
derivatives and non-derivative instruments at the end 
on the reporting period.
If interest rates had been 100 basis points higher/
lower and all other variables were held constant, the 
Group’s loss for the year ended 30 June 2025 would 
(decrease)/increase by $50,497 (2024: $62,054)
17.6	Foreign currency risk management
The Group undertakes transactions denominated 
in foreign currencies; consequently, exposures to 
exchange rate fluctuations arise. At 30 June 2025, 
the Company had cash denominated in US dollars 
US$349 (2024: US$211,770). The A$ equivalent at 30 
June 2025 is $533 (2024: $317,651). A 5% movement 
in foreign exchange rates would increase or (decrease) 
the Group’s loss before tax by approximately $27 
(2024: $15,833).  Exchange rate exposures are 
managed within approved policy parameters utilising 
forward foreign exchange contracts.  As at 30 June 
2025, the Group has not entered in any forward 
foreign exchange contracts.
17.7	Credit risk management
Credit risk refers to the risk that a counterparty will 
default on its contractual obligations resulting in 
financial loss to the Group. The Group has adopted 
a policy of dealing with creditworthy counterparties 
and obtaining sufficient collateral, where appropriate, 
as a means of mitigating the risk of financial loss 
from defaults. The Group only transacts with 
entities that are rated the equivalent of investment 
grade and above. This information is supplied by 
independent rating agencies where available and, if 
not available, the Group uses other publicly available 
financial information and its own trading records 
to rate its major customers. The Group’s exposure 
and the credit ratings of its counterparties are 
continuously monitored and the aggregate value of 
transactions concluded is spread amongst approved 
counterparties.
The credit risk on liquid funds is limited because the 
counterparties are banks with high credit-ratings 
assigned by international credit-rating agencies.
17.8	Liquidity risk management
Ultimate responsibility for liquidity risk management 
rests with the board of directors, which has 
established an appropriate liquidity risk management 
framework for the management of the Group’s 
short-, medium- and long-term funding and liquidity 
management requirements. The Group manages 
liquidity by maintaining adequate banking facilities, 
by continuously monitoring forecast and actual 
cash flows, and by matching the maturity profiles of 
financial assets and liabilities.

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72
Contractual cash flows
Carrying 
Amount
Less than 1 
month
1-3 months
3-12 
months
1 year to 5 
years
Total 
contractual 
cash flows
$
$
$
$
$
$
2025
Trade and other payables
941,058
941,058
-
-
-
941,058
2024
Trade and other payables
950,627
950,627
-
-
-
950,627
18.	Share-based payments
Options may be issued to external consultants or non-
related parties without shareholders’ approval, where 
the annual 15% capacity pursuant to ASX Listing Rule 
7.1 has not been exceeded.  Options cannot be offered 
to a director or an associate of a director except where 
approval is given by shareholders at a general meeting.
Each option converts into one ordinary share of Cynata 
Therapeutics Limited on exercise. The options carry 
neither right to dividends nor voting rights. Options may 
be exercised at any time from the date of vesting to the 
date of their expiry.
The following share-based payment arrangements 
were in existence at balance date (30 June 2025):
Option series
Number
Grant date
Grant date 
fair value
Exercise price
Expiry date
Vesting date
CYPAB (i)
4,500,000
24 Nov 2020
$0.493
$0.970
29 Nov 2025
Vested
CYPAD (ii)
1,000,000
11 Oct 2021
$0.156
$0.89
11 Oct 2025
Various
CYPAR (iii)
300,000
22 Nov 2022
$0.135
$0.51
23 Nov 2027
Various
CYPAS (iv)
2,033,333
30 Jun 2023
$0.075
$0.176
30 Jun 2028
Various
CYPAE (v)
1,910,000
13 Nov 2023
$0.079
$0.185
20 Nov 2028
Various
CYPAF (vi)
975,000
16 Jan 2024
$0.084
$0.195
16 Jan 2029
Various
CYPAT (vii)
1,800,000
17 Apr 2024
$0.144
$0.290
17 Apr 2029
Various
CYPAU (viii)
1,000,000
13 Sep 2024
$0.190
$0.280
12 Sep 2028
Various
CYPAG (ix)
1,000,000
1 Oct 2024
n/a
$0.300
2 Apr 2026
Vested
CYPAH (ix)
1,000,000
1 Oct 2024
n/a
$0.400
2 Apr 2026
Vested
CYPAL (ix)
1,000,000
1 Oct 2024
n/a
$0.500
2 Apr 2026
Vested
CYPAV (x)
500,000
10 Jun 2025
n/a
$0.400
10 Sep 2026
Vested
CYPAW (x)
750,000
10 Jun 2025
n/a
$0.500
10 Sep 2026
Vested
CYPAX (x)
1,750,000
10 Jun 2025
n/a
$0.600
10 Sep 2026
Vested
(i)	
Unlisted options issued to Directors and former Directors 
pursuant to an Employee Option Acquisition Plan.
(ii)	 Unlisted options issued to Dr Airey pursuant to an 
Employee Option Acquisition Plan.
(iii)	 Unlisted options issued to Ms Rolfe pursuant to the 
terms of her appointment as non-executive director.
(iv)	 Unlisted options issued to Dr Kelly (2,000,000) pursuant 
to the terms of his appointment as Managing Director & 
CEO and to a former Director.
Financial instruments (cont’d)

73
Notes
73
(v)	 Unlisted options issued to Dr Brooke (500,000), Dr Kelly 
(750,000), Dr Maher (220,000), Ms Rolfe (220,000) 
and Dr Wotton (220,000) to ensure alignment with 
shareholders’ interests and to maximise Company value.
(vi)	 Unlisted options issued to Dr Airey (500,000), Mr Webse 
(125,000) and other employees of the Company (350,000) 
pursuant to an Employee Option Acquisition Plan.
(vii)	 Unlisted options issued to Dr Kroll pursuant to an 
Employee Option Acquisition Plan.
(viii)	Unlisted options issued to an external consultant under 
Cynata Equity Incentive Plan in lieu of payment of fees.
(ix)	 Unlisted options issued to the lead broker of the 
Institutional Placement pursuant to a Corporate 
Advisory Mandate.  These options were issued for 
$0.00001 per option and the Company received $30 
cash consideration.
(x)	 Unlisted options issued to the lead broker of the 
Institutional Placement pursuant to a Corporate 
Advisory Mandate.  These options were issued for 
$0.00001 per option and the Company received $30 
cash consideration.
There has been no alteration to the terms and 
conditions of the above options arrangements since 
the grant date.
18.1	Fair value of share options
Options were priced using the Black-Scholes pricing 
model. Expected volatility is based on the historical 
share price volatility over the past 12 months from 
grant date.
Unlisted options issued to the lead broker (ix) and 
(x) have been recorded using the cash consideration 
received. A Black-Scholes pricing model has been 
used as a comparison under AASB2 which include the 
following inputs (a) Exercise price $0.40, $0.50 & $0.60 
(b) Grant date fair value $0.215 & $0.172, (c) Volatility 
70% (d) Risk-free rate 3.27%. The fair value using B&S 
for the options issued was not considered materially 
different to the cash consideration received.
Where relevant, the fair value of the options has been 
adjusted based on management’s best estimate for 
the effects of non-transferability of the options.
The weighted average exercise price of options 
granted during the year is $0.444 (2024: $0.227).
The inputs to the Black-Scholes pricing model were as 
follows:
Inputs
CYPAU
Number of options
1,000,000
Grant date
13 Sept 2024
Grant date fair value
$0.19
Exercise price
$0.28
Expected volatility
93%
Implied option life (years)
4.0
Expected dividend yield
n/a
Risk-free rate
3.50%

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74
18.2	Movements in share options during the year
The following reconciles the share options outstanding at the beginning and end of the year:
2025
2024
Number of 
options
Weighted 
average 
exercise price
Number of 
options
Weighted 
average 
exercise price
No.
$
No.
$
Balance at beginning of the year
31,895,970
0.423
27,777,637
0.471
Granted during the year
7,000,000
0.444
4,685,000
0.227
Forfeited during the year
-
-
-
-
Exercised during the year
(72,917)
0.300
-
-
Expired during the year
(19,304,720)
0.343
(566,667)
1.200
Balance at end of year
19,518,333
0.509
31,895,970
0.423
Exercisable at end of year
7,332,826
0.856
7,648,960
0.990
18.3	Share options exercised during the year
The following share options were exercised during the year (2024: nil):
Option series
Number exercised
Exercise date
Share price at exercise date
CYPOA
3,150
19 Jul 2024
$0.26
CYPOA
69,767
20 Feb 2025
$0.24
18.4	Share options outstanding at the end of the year
Share options outstanding at the end of the year 
had a weighted average exercise price of $0.509 
(2024: $0.423) and a weighted average remaining 
contractual life of 651 days (2024: 597 days).
Share-based payments (cont’d)

75
Notes
75
19.	Key management personnel
The aggregate compensation made to directors and other members of key management personnel of the Group 
is set out below:
2025
2024
$
$
Short-term employee benefits
1,497,663
1,151,231
Post-employment benefits
91,404
122,948
Share-based payments
212,464
172,114
1,801,531
1,446,293
Short-term employee benefits
These amounts include fees paid to non-executive 
directors, accrued bonuses, salary and paid leave 
benefits awarded to executive directors and key 
management personnel and fees paid to entities 
controlled by the directors.
Post-employment benefits
These amounts are superannuation contributions 
made during the year.
Share-based payments
These amounts represent the expense related to the 
participation of key management personnel in equity 
-settled benefit schemes as measured by the fair value 
of the options granted on grant date.
Further information in relation to key management 
personnel remuneration can be found in the 
remuneration report contained in the directors’ report.
20.	Related party transactions
20.1	Entities under the control of the Group
The Group consists of the parent entity, Cynata 
Therapeutics Limited and its wholly-owned Ireland-
based subsidiary Cynata Therapeutics Ireland Limited 
and US-based subsidiary Cynata Incorporated, which 
in turns controls 100% of Cynata Australia Pty Ltd, the 
non-operating entity of Cynata Incorporated.
Balances and transactions between the parent entity 
and its subsidiaries, which are related parties of the 
entity, have been eliminated on consolidation and are 
not disclosed in this note.
20.2	Key management personnel
Any person(s) having authority and responsibility for 
planning, directing and controlling the activities of 
the entity, directly or indirectly, including any director 
(whether executive or otherwise) of that entity, are 
considered key management personnel.
For details of disclosures relating to key management 
personnel, refer to the remuneration report contained 
in the directors’ report, note 18 and note 19.
Transactions with related parties are on normal 
commercial terms and conditions no more favourable 
than those available to other parties unless otherwise 
stated.

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Cynata Therapeutics Annual Report 2024/2025
76
21.	Cash and cash equivalents
Cash and cash equivalents at the end of the reporting 
period as shown in the consolidated statement of 
cash flows can be reconciled to the related items in 
the consolidated statement of financial position as 
follows:



2025
2024
$
$
Cash and bank balances
5,049,744
6,205,418
21.1	Reconciliation of loss for the year to net cash flows from operating activities
2025
2024
$
$
Cash flow from operating activities
Loss for the year
(9,390,586)
(9,744,709)
Adjustments for:
Share-based payments
260,415
228,463
Amortisation expenses
282,964
280,732
Effects of exchange rate changes
10
1,377
Movements in working capital
  Decrease in trade and other receivables and prepayments
31,735
362,807
  Increase/(decrease) in trade and other payables
40,432
(1,116,766)
  Increase in annual leave provisions
54,695
27,535
Net cash outflows from operating activities
(8,720,335)
(9,960,561)
22.	Contingent liabilities and contingent assets
The directors are not aware of any significant 
contingencies at balance date other than a 
requirement for the payment of royalties pursuant to 
certain license agreements should future revenues 
exceed predetermined thresholds.

77
Notes
77
23.	Commitments for expenditure
The Group has entered into several agreements 
related to research and development activities. As at 
30 June 2025, under these agreements, the Company 
is committed to making payments over future periods, 
as follows:



$
During the period 1 July 2025 – 30 June 2026
3,345,195
During the period 1 July 2026 – 30 June 2027
2,106,753
During the period 1 July 2027 – 30 June 2028
1,496,502
Where commitments are denominated in foreign 
currencies, the amounts have been converted to 
Australian dollars based on exchange rates prevailing 
as at 30 June 2025. The Company has the right to 
terminate the relevant agreements with notice periods 
that vary between agreements. The committed 
payments listed above could be materially reduced 
if the Company chooses to terminate some or all the 
relevant agreements.
24.	Remuneration of auditors
Auditor of the Group
2025
2024
$
$
Audit and review of the financial statements
59,507
56,036
The auditor of the Group is Stantons.

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Cynata Therapeutics Annual Report 2024/2025
78
25.	Parent entity information
The accounting policies of the parent entity, which 
have been applied in determining the financial 
information shown below, are the same as those 
applied in the consolidated financial statements.  
Refer to note 3 for a summary of significant 
accounting policies relating to the Group.
Financial position
2025
2024
$
$
Assets
Current assets
5,349,013
6,536,422
Non-current assets
258,447
-
Total assets
5,607,460
6,536,422
Liabilities
Current liabilities
941,058
950,627
Provisions
275,123
220,428
Total liabilities
1,216,181
1,171,055
Net assets
4,391,279
5,365,367
Equity
Issued capital
89,519,207
81,624,596
Reserves
8,166,906
7,906,430
Accumulated losses
(93,294,834)
(84,165,659)
Total equity
4,391,279
5,365,367
Financial performance
Loss for the year
(9,129,175)
(9,463,976)
Commitments and contingencies
There were no material commitments or contingencies 
at the reporting date for the parent company except 
for those mentioned in note 22 and note 23 above.

79
Notes
79
26.	Events after the reporting period
On 22 August 2025, the Company entered into an 
At-the-Market Subscription Agreement (“ATM”) with 
Acuity Capital. The ATM provides Cynata with up to 
$7,500,000 of standby equity capital over the coming 
five years, to 31 July 2030.  Cynata has full discretion 
as to whether or not to utilise the ATM, the maximum 
number of shares to be issued, the minimum issue 
price of shares and the timing of each subscription 
(if any). Cynata may terminate the ATM at any time, 
without cost or penalty. As security, the Company has 
issued 11,500,000 fully paid ordinary shares in the 
Company at nil cash consideration.
Other than the above, there has not been any matter 
or circumstance occurring subsequent to the end of 
the financial year that has significantly affected, or 
may significantly affect, the operations of the Group, 
the results of those operations, or state of affairs of 
the Group in future financial years.
27.	Approval of financial statements
The financial statements were approved by the board 
of directors and authorised for issue on 28 August 
2025.

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80
Consolidated Entity Disclosure Statement
Entity name
Entity type
Country of 
incorporation
Ownership 
interest
Tax residency
Cynata Incorporated 
Company
United States of 
America
100%
United States of 
America
Cynata Therapeutics Ireland Limited
Company
Ireland
100%
Ireland
Cynata Australia Pty Ltd
Proprietary limited
Australia
100%
Australia
Basis of preparation
Key assumptions and judgements 
Determination of Tax Residency 
Section 295 (3A) of the Corporation Acts 2001 
requires that the tax residency of each entity which 
is included in the Consolidated Entity Disclosure 
Statement (CEDS) be disclosed. For the purposes of 
this section, an entity is an Australian resident at the 
end of a financial year if the entity is: 
a)	
an Australian resident (within the meaning of the 
Income Tax Assessment Act 1997) at that time; 
or 
b)	
a partnership, with at least one partner being an 
Australian resident (within the meaning of the 
Income Tax Assessment Act 1997) at that time; 
or 
c)	
a resident trust estate (within the meaning 
of Division 6 of Part III of the Income Tax 
Assessment Act 1936) in relation to the year of 
income (within the meaning of that Act) that 
corresponds to the financial year. 
The determination of tax residency involves judgment 
as the determination of tax residency is highly fact 
dependent and there are currently several different 
interpretations that could be adopted, and which 
could give rise to a different conclusion on residency. 
In determining tax residency, the consolidated entity 
has applied the following interpretations: 
	
z
	Australian tax residency 
The consolidated entity has applied current 
legislation and judicial precedent, including 
having regard to the Commissioner of Taxation’s 
public guidance in Tax Ruling TR 2018/5. 
	
z
Foreign tax residency 
The consolidated entity has applied current 
legislation and where available judicial precedent 
in the determination of foreign tax residency. 
Where necessary, the consolidated entity 
has used independent tax advisers in foreign 
jurisdictions to assist in its determination of 
tax residency to ensure applicable foreign tax 
legislation has been complied with. 

81
Notes
81

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82
Substantial Shareholders
The names of the substantial shareholders as at 
22 August 2025 are:
Name
Shares Held
Issued Capital
No.
%
Phillip Asset Management Ltd atf BioScience Managers Translation Fund I
23,588,040
9.93
FIL Investment Management (Hong Kong) Limited
20,967,806
8.83
Distribution of Ordinary Shares
Category
Holders
Ordinary Shares
Issued Capital
No.
No.
%
1 – 1,000
568
331,734
0.14
1,001 – 5,000
907
2,520,509
1.06
5,001 – 10,000
386
3,057,133
1.29
10,001 – 100,000
928
34,724,351
14.62
100,001 and over
275
196,820,642
82.89
3,094
237,454,369
100.00
ASX Additional Information  
As at 22 August 2025

83
ASX Additional Information 
83
Voting Rights
(a)	
at meetings of members each member entitled to 
vote may vote in person or by proxy or attorney; 
(b)	
on a show of hands each person present who is a 
member has one vote, and on a poll each person 
present in person or by proxy or by attorney has 
one vote for each ordinary share held; and
(c)	
no voting rights attach to listed and unlisted 
options.









Number of Holders of Unlisted Options
	
z
4,500,000 unlisted Options exercisable at $0.97 
and expiring 29/11/2025 held by 6 holders. 
Holders holding more than 20% being 2,000,000 
held in the name of Dr Geoffrey Brooke (44.44%) 
and 1,500,000 held in the name of Dr Ross 
Macdonald (33.33%).
	
z
1,000,000 unlisted Options issued under 
the Employee Share Option Acquisition Plan 
exercisable at $0.89 Options and expiring 
11/10/2025 held by 1 holder.
	
z
1,000,000 unlisted Options exercisable at $0.30 
and expiring 2/04/2026 held by 1 holder, Zenix 
Nominees Pty Ltd.
	
z
1,000,000 unlisted Options exercisable at $0.40 
and expiring 2/04/2026 held by 1 holder, Zenix 
Nominees Pty Ltd.
	
z
1,000,000 unlisted Options exercisable at $0.50 
and expiring 2/04/2026 held by 1 holder, Zenix 
Nominees Pty Ltd.
	
z
500,000 unlisted Options exercisable at $0.40 
and expiring 10/09/2026 held by 1 holder, Zenix 
Nominees Pty Ltd.
	
z
750,000 unlisted Options exercisable at $0.50 
and expiring 10/09/2026 held by 1 holder, Zenix 
Nominees Pty Ltd.
	
z
1,750,000 unlisted Options exercisable at $0.60 
and expiring 10/09/2026 held by 1 holder, Zenix 
Nominees Pty Ltd.
	
z
300,000 unlisted Options exercisable at $0.51 
and expiring 23/11/2027 held by 1 holder, Ms 
Janine Rolfe.
	
z
2,033,333 unlisted Options exercisable at $0.176 
and expiring 30/06/2028, held by 2 holders. 
Holder holding more than 20% being 2,000,000 
in the name of Dr Kilian Kelly (98.36%).
	
z
1,000,000 unlisted Options issued under the 
Equity Incentive Plan exercisable at $0.28 and 
expiring 12/9/2028, held by 1 holder.
	
z
1,910,000 unlisted Options exercisable at $0.185 
and expiring 20/11/2028 held by 5 holders. 
Holders holding more than 20% being 750,000 
held in the name of Mrs Tamara Kelly (39.27%) 
and 500,000 being held in the name of Dalhigh 
Pty Ltd  (26.18%).
	
z
975,000 unlisted Options issued under the 
Employee Share Option Acquisition Plan 
exercisable at $0.195 Options and expiring 
16/01/2029, held by 5 holders.
	
z
1,800,000 unlisted Options issued under 
the Employee Share Option Acquisition Plan 
exercisable at $0.29 Options and expiring 
17/04/2029, held by 1 holder.




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Cynata Therapeutics Annual Report 2024/2025
84
ASX Additional Information (cont’d)
20 Largest Shareholders
Name
Shares Held
Issued Capital
No.
%
Phillip Asset Management Limited 
23,588,040
9.93
HSBC Custody Nominees (Australia) Limited
18,773,698
7.91
Acuity Capital Investment Management Pty Ltd 
11,500,000
4.84
Citicorp Nominees Pty Limited
10,616,446
4.47
Fujifilm Corporation
8,088,403
3.41
National Nominees Limited
7,446,576
3.14
BNP Paribas Nominees Pty Ltd 
4,832,757
2.04
J P Morgan Nominees Australia Pty Limited
4,288,146
1.81
Mr Craig Lawrence Darby
4,213,853
1.77
BNP Paribas Nominees Pty Ltd 
4,103,770
1.73
Kenneth Adrian Raymond Wilson
3,549,905
1.50
Agati Pty Ltd
2,803,862
1.18
Dr Ross Alexander Macdonald
2,000,000
0.84
Mrs Aily Lamb
1,950,000
0.82
Mr David Charles Prodrick
1,700,138
0.72
BNP Paribas Noms Pty Ltd
1,664,747
0.70
Mr Patrick Anthony Walsh
1,594,610
0.67
Mal Washer Nominees Pty Ltd 
1,559,534
0.66
Mr Pawel Rej & Mrs Miroslawa Rej
1,543,036
0.65
Crosswind Trustee Company Limited 
1,520,000
0.64
117,337,521
49.41
Restricted Securities
There are no ASX restricted securities on issue.
On-Market Buy-Back
There is no current on-market buy back.
Unmarketable Parcels
The number of shareholders holding less than a 
marketable parcel is 1,069.


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AUSTRALIA
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Email: 	info@cynata.com
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