OptimizeRx
Annual Report 2016

Plain-text annual report

UNITED STATESSECURITIES AND EXCHANGE COMMISSIONWASHINGTON, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2016 ☐ TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from _________ to ________ Commission file number: 000-53605 OptimizeRx Corporation(Exact name of registrant as specified in its charter) Nevada 26-1265381(State or other jurisdiction of incorporation or organization) (I.R.S. Employer Identification No.) 400 Water Street, Ste. 200Rochester, MI 48307(Address of principal executive offices) (Zip Code) Registrant’s telephone number: 248-651-6568 Securities registered under Section 12(b) of the Exchange Act: Title of each class Name of each exchange on which registerednone not applicable Securities registered under Section 12(g) of the Exchange Act: Title of each classCommon Stock, par value of $0.001 Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes ☐☐ No ☒☒ Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes ☐☐ No ☒☒ Indicate by checkmark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 duringthe preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirementsfor the past 90 days. Yes ☒☒ No ☐☐ Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required tobe submitted and posted pursuant to Rule 405 of Regulation S-T (§ 229.405 of this chapter) during the preceding 12 months (or for such shorter period thatthe registrant was required to submit and post such files). Yes ☒☒ No ☐☐ Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K (§ 232.405 of this chapter) is not contained herein, and willnot be contained, to the best of registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K orany amendment to this Form 10-K. Yes ☐☐ No ☒☒ Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. ☐☐ Large accelerated filer☐☐ Accelerated filer☐☐ Non-accelerated filer☒☒ Smaller reporting company Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐☐ No ☒☒ State the aggregate market value of the voting and non-voting common equity held by non-affiliates computed by reference to the price at which thecommon equity was last sold, or the average bid and asked price of such common equity, as of the last business day of the registrant’s most recentlycompleted second fiscal quarter. $22,330,191 Indicate the number of shares outstanding of each of the registrant’s classes of common stock, as of the latest practicable date. 29,718,867 common shares asof March 1, 2017  TABLE OF CONTENTS Page PART I Item 1.Business1Item 1A.Risk Factors6Item 2.Properties11Item 3.Legal Proceedings11Item 4.Mine Safety Disclosures11 PART II Item 5.Market for Registrant’s Common Equity and Related Stockholder Matters and Issuer Purchases of Equity Securities12Item 7.Management’s Discussion and Analysis of Financial Condition and Results of Operations14Item 8.Financial Statements and Supplementary Data19Item 9.Changes In and Disagreements With Accountants on Accounting and Financial Disclosure21Item 9A.Controls and Procedures21Item 9B.Other Information22 PART III Item 10.Directors, Executive Officers and Corporate Governance22Item 11.Executive Compensation29Item 12.Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters32Item 13.Certain Relationships and Related Transactions, and Director Independence33Item 14.Principal Accountant Fees and Services35 PART IV Item 15.Exhibits, Financial Statement Schedules36  PART I Item 1. Business Company Highlights For 2016 1)Our sales for 2016 were $7.75 million, a 7.5% increase over 2015. 2)Our sales for Q4 2016 were approximately $2.3 million, a 13% increase over the same period in 2015. 3)In 2016, we distributed financial messages related to approximately 95 different brands and 25 of the leading pharmaceutical companies. 4)We acquired all available messaging inventory in the Allscripts LogRx messaging platform for Q4 of 2016 and calendar 2017, effectively giving usexclusive sales rights and the opportunity to substantially increase our brand messaging revenue. 5)We continue to integrate with WPP’s companies and saw a considerable increase in activity in Q4 of 2016. We expect this relationship to continueto help us expand into more manufacturers, brands and products, with activity related to approximately 25 brands in 2016. 6)We expanded our leadership and support teams in 2016 and established a strong base to position ourselves for accelerated revenue growth in 2017and beyond. 7)We continued to acquire new pharmaceutical manufacturers and brands for distribution through our expanding channel partners, which include,Allscripts, Practice Fusion, Care360, DrFirst and others. 8)We doubled our sales force from 2 to 4 in 2016 and added a 5th sales executive in January 2017 to accelerate revenue growth, brand expansion andnew product sales. 9)We continued to prove outstanding Returns on Investment associated with our pharmaceutical promotions through an independent analytics firmwith multiple pharmaceutical brands that differentiates our programs as one of the most effective digital tactics available to pharmaceutical firms. Our success in acquiring, integrating and expanding into new promotional EHR/eRx platforms continues to grow as well. Pharmaceutical Sales and Marketing Updates Our sales team continues to expand opportunities within existing clients and close opportunities with new clients. We are focused on adding additionalbrands for existing clients, expanding the utilization of our network for existing brands, and obtaining new clients. Additionally, we are expanding our service offerings as follows: ●Brand Messaging – we have successfully integrated our new platform with 2 partners and are currently testing. We expect revenue in the second halfof 2017. Additionally, we expect our exclusive partnership with Allscripts that allows us to offer LogRx brand messaging to accelerate revenuegrowth in this area.●Brand Support/New Drug File Integration – we have designed a service to better insure that manufacturers’ brands are available in every ePrescribingplatform available and we have incorporated this to an overall program related to launch brands that includes brand awareness messaging andfinancial messaging.●ePrescribe Training – we are pursuing opportunities to leverage our partnership with WPP/Grey to train representatives on understanding andleveraging EHR sales opportunities. 1  We are also continuing to ramp up our marketing efforts as follows: ●Held multiple meetings, including some initiated and arranged by pharmaceutical companies, to bring on new Health Systems/ePrescribe Platforms. ●Spoke at Coupon and Co-Pay Off-set Strategies Conference.●Spoke at multiple conferences in 2016, including the Liolios 5th annual Gateway conference and the 28th annual Roth Investor conference.●Sponsored the 4th Annual ePrescribe/EHR Pharmaceutical Conference. With the growth of both the number of our pharmaceutical brands and our distribution network, we expect that our distribution of financial messages willcontinue to increase substantially in 2017. Operational Update In 2017, in addition to expanding our existing network, we plan to intensively focus on increasing physician utilization of our partner networks. Wecontinue to work individually with each of our partners based on their particular situation to improve workflow to increase coupon utilization by thoseproviders that have access, obtain access for those prescribers that currently do not have financial messaging access, and increase overall revenue derivedfrom each channel. We believe there is significant revenue growth available within our existing brands by better utilizing our existing partner networks, inaddition to the revenue growth provided by new brands and new network partners. We signed an agreement in 2015 with Allscripts to become their exclusive provider of financial messaging and to obtain access to their Touchworks EHRproduct, which is used primarily by large health systems. We expect financial messaging activity to commence within Touchworks in the first quarter of 2017and to continue to ramp up throughout the year. We expect this launch to have a significant impact on our revenue growth. Technology Updates To support our growth, we have migrated our platform to Oracle database software. Our system can manage up to 1 million rules and return the appropriatecontent within 1 second. This allows unsurpassed response time to avoid delays, and gives us the ability to meet the upcoming accelerated revenue growththat we expect. We have developed our own proprietary brand messaging system that will expand our ability to deliver key clinical messages in addition to financial supportand plan to integrate this within EHRs that currently do not offer this valued product to their providers. We are currently testing this system with our firstpartner and expect to launch this messaging system in the first half of 2017 and then expand to other channels as well. Summary Despite the lengthy sales cycle involved in creating this new financial messaging market, we remain very excited about our core financial messagingbusiness and expect to significantly accelerate revenue growth in 2017 with the launch of additional channels, brands and products. We expect our activenetwork to grow substantially in 2017. Principal Products and Applications Our principal products and applications can be summarized as follows: ●Financial Messaging – Our integrated financial messaging platform is a revolutionary virtual "Patient Support Center" that allows doctors and staffto access a universe of sample vouchers, co-pay coupons and other patient support through their EMR and/or e-Prescribe systems to search, print orelectronically dispense directly to patients and a national network of pharmacies. Our platform eliminates the need for physicians to manage andstore physical drug samples by offering a more convenient and efficient way to allocate, administer and track samples and co-pay savings providedto their patients. Today, almost 60% of doctors’ offices ban or limit drug representatives and the samples they offer. Although samples are stillvaluable, many healthcare systems and doctors are looking for an easier, more effective way to increase affordable access and adherence to theirprescribed branded medications. 2  ●Brand Messaging – Our brand messaging services include a variety of brand awareness and clinical messaging services that can be tailored to meetthe needs of a brand. These messages can include brand awareness messages, reminder ads, clinical messages, and unbranded messages that can betargeted by specialty, diagnostic code, and other criteria. Brand messaging is highly complementary to our core financial messaging product.Historically, we have sold brand messaging based on specific products offered by our EHR partners, but we have developed our own proprietarybrand messaging system and expect to roll that product out in 2017. We have also purchased all available 2017 inventory from Allscripts for itsLogRx brand messaging product. We believe brand messaging represents a significant growth opportunity for us.●Brand Support – Our brand support is focused on educating and working with pharmaceutical manufacturers on identifying, formulating, andimplementing new eRx media strategies for promoting their products. Our services include: 1) Drug File Integration - a service designed to betterinsure that manufacturers’ drugs are present in every ePrescribing platform available; 2) Sales Force Training – a service to educate the extendedfield sales force on this new integrated solution and what to look for within their client base to insure maximum exposure of their brands; and 3)Strategy Development – a service that assists manufactures in identifying and building a competitive strategy to take advantage of this new digitalfrontier. Currently, this activity results in less than 10% of our revenue, but represents a significant growth opportunity for us. Marketing and Sales We continue to extend our marketing efforts to build both brand and capabilities awareness in the market. As previously discussed, we continue to activelyparticipate in industry and partner events such as exlPharma and the ACE – Allscripts Users Conference, as well as having taken a lead sponsor position inthe CBInet eRx and EHR conferences in March of 2016. We are also the named sponsor of the March 2017 conference. During the course of the year, we alsoinitiated and delivered successful email marketing campaigns, which generated viable leads for our sales force. In 2016, we completed an update of our corporate branding including updating our website and marketing materials. We also continue to focus on the expansion of our strategic partnership with WPP/Grey Health Group, a leading agency within the healthcare marketplace,which included a significant investment by an affiliated entity of WPP in 2015. We plan to continue to increase our marketing efforts with all of our strategicpartners, as we intend to continue to promote our platform primarily through the following: ●Industry and Partner Events;●Email Campaigns;●Internet Marketing;●Public Relations Campaigns;●Physician Offices;●Direct to Consumer Marketing;●Trade Media Advertising;●Pharmacy Partners;●Physician Organizations and Associations; and●Strategic Relationships. Competition Our platform competes in the highly competitive pharmaceutical and healthcare digital marketing industry that is dominated by large well-known companieswith established names, solid market niches, wide arrays of product offerings and marketing networks. Our financial messaging offerings compete forpharmaceutical budgets with a variety of other forms of advertising and promotion. 3  Despite these overall competitors, we do not have major competition in our specific portion of the financial messaging market. We have been experiencing agrowing list of potential partners whom either have content that they want to deliver through our distribution engine and network, or whom havecomplementary technology and want to integrate our solution as a channel partner, expanding our reach to clinicians. The primary direct competitors in ourspace of the market are ConnectiveRx and Aptus Health. However, we believe our breadth of brands offered, extensive list of pharmaceutical clients, and thevast reach of our network give us a substantial advantage and allow us to achieve a dominant position in the marketplace. Intellectual Property In 2012, we were awarded a patent for our innovative solution (US Patent No. 8,341,015). This award was a result of our extensive research and developmentefforts. The awarded claims cover our ability to electronically process, display and distribute eligible prescription savings on the medications and therapieshealthcare providers wish to prescribe for their patients. We use a nationally ranked intellectual property law firm to further expand and protect our intellectual property. Through them, we have filed two additionalpatents on our technology. We believe our current and expanding IP will allow us to continue being the leader in this rapidly growing space. We stand readyto prepare additional filings, as necessary, to protect our intellectual property on any forthcoming solutions that will further assist and support physicians,pharmacists and patients. OPTIMIZERx and SampleMD are our licensed trademarks. Government Regulation Fraud and Abuse Laws Anti-Kickback Statutes The federal healthcare program Anti-Kickback Statute prohibits persons from knowingly and willfully soliciting, offering, receiving or providingremuneration, directly or indirectly, in exchange for or to induce either the referral of an individual for, or the furnishing, arranging for or recommending agood or service for which payment may be made in whole or part under a federal healthcare program such as Medicare or Medicaid. The definition ofremuneration has been broadly interpreted to include anything of value, including for example gifts, discounts, the furnishing of supplies or equipment,credit arrangements, payments of cash and waivers of payments. Several courts have interpreted the statute's intent requirement to mean that if any onepurpose of an arrangement involving remuneration is to induce referrals or otherwise generate business involving goods or services reimbursed in whole or inpart under federal healthcare programs, the statute has been violated. The law contains a few statutory exceptions, including payments to bona fideemployees, certain discounts and certain payments to group purchasing organizations. Violations can result in significant penalties, imprisonment andexclusion from Medicare, Medicaid and other federal healthcare programs. Exclusion of a manufacturer would preclude any federal healthcare program frompaying for its products. In addition, kickback arrangements can provide the basis for an action under the Federal False Claims Act, which is discussed in moredetail below. The Anti-Kickback Statute is broad and potentially prohibits many arrangements and practices that are lawful in businesses outside of thehealthcare industry. Recognizing that the Anti-Kickback Statute is broad and may technically prohibit many innocuous or beneficial arrangements, theOffice of Inspector General of Health and Human Services, or OIG, issued a series of regulations, known as the safe harbors, beginning in July 1991. Thesesafe harbors set forth provisions that, if all the applicable requirements are met, will assure healthcare providers and other parties that they will not beprosecuted under the Anti-Kickback Statute. The failure of a transaction or arrangement to fit precisely within one or more safe harbors does not necessarilymean that it is illegal or that prosecution will be pursued. However, conduct and business arrangements that do not fully satisfy each applicable safe harbormay result in increased scrutiny by government enforcement authorities such as the OIG. Arrangements that implicate the Anti-Kickback Law, and that do notfall within a safe harbor, are analyzed by the OIG on a case-by-case basis. Government officials have focused recent enforcement efforts on, among otherthings, the sales and marketing activities of healthcare companies, and recently have brought cases against individuals or entities with personnel whoallegedly offered unlawful inducements to potential or existing customers in an attempt to procure their business. Settlements of these cases by healthcarecompanies have involved significant fines and/or penalties and in some instances criminal pleas. In addition to the Federal Anti-Kickback Statute, manystates have their own kickback laws. Often, these laws closely follow the language of the federal law, although they do not always have the same exceptionsor safe harbors. In some states, these anti-kickback laws apply with respect to all payors, including commercial health insurance companies. 4  False Claims Laws Federal false claims laws prohibit any person from knowingly presenting, or causing to be presented, a false claim for payment to the federal government orknowingly making, or causing to be made, a false statement to get a false claim paid. Manufacturers can be held liable under false claims laws, even if they donot submit claims to the government, if they are found to have caused submission of false claims. The Federal Civil False Claims Act also includes whistleblower provisions that allow private citizens to bring suit against an entity or individual on behalf of the United States and to recover a portion of anymonetary recovery. Many of the recent highly publicized settlements in the healthcare industry related to sales and marketing practices have been casesbrought under the False Claims Act. The majority of states also have statutes or regulations similar to the federal false claims laws, which apply to items andservices reimbursed under Medicaid and other state programs, or, in several states, apply regardless of the payor. Sanctions under these federal and state lawsmay include civil monetary penalties, exclusion of a manufacturer's products from reimbursement under government programs, criminal fines andimprisonment. Privacy and Security The Health Insurance Portability and Accountability Act of 1996, or HIPAA, and the rules promulgated there under require certain entities, referred to ascovered entities, to comply with established standards, including standards regarding the privacy and security of protected health information, or PHI. HIPAAfurther requires that covered entities enter into agreements meeting certain regulatory requirements with their business associates, as such term is defined byHIPAA, which, among other things, obligate the business associates to safeguard the covered entity's PHI against improper use and disclosure. While notdirectly regulated by HIPAA, our customers or distributors might face significant contractual liability pursuant to such an agreement if the business associatebreaches the agreement or causes the covered entity to fail to comply with HIPAA. It is possible that HIPPA compliance could become a substantialregulatory burden and expense to our operations, although we do not believe that this will occur as a general website publisher. Employees As of December 31, 2016, we had 19 full-time employees and 1 part-time employee, in addition to contracted programmers, as needed, through ourestablished relationship with Simple eSolutions, a technical and programming resources partner. Subsidiaries We conduct our operations through our wholly-owned subsidiary, OptimizeRx Corporation, a Michigan corporation. 5  Item 1A. Risk Factors Risks Relating to Business and Financial Condition Because we have historically experienced losses, if we are unable to achieve profitability, our financial condition and company could suffer. Since the inception of our business we have historically incurred losses. While we have increased revenues significantly, we have not yet been able toachieve profitability due to significant investments in our growth and non-cash expenses. Our ability to achieve consistent profitability depends on ourability to generate sales through our technology platform and advertising model, while maintaining reasonable expense levels. If we do not achievesustainable profitability, it may impact our ability to continue our operations. Our business and growth may suffer if we are unable to attract and retain key employees. Our success depends on the expertise of our executive officers and certain other key technical personnel. It may be difficult to find sufficiently qualifiedindividuals to replace management or other key technical personnel in the event of death, disability or resignation, thus frustrating our ability to implementour business plan, which could negatively affect our operating results. Furthermore, our ability to expand operations to accommodate our anticipated growth will also depend on our ability to attract and retain qualified media,management, finance, marketing, sales and technical personnel. However, competition for these types of employees is intense due to the limited number ofqualified professionals. Our ability to meet our business development objectives will depend in part on our ability to recruit, train and retain top qualitypeople with advanced skills who understand our technology and business. If we are unable to engage and retain the necessary personnel, our business may bematerially and adversely affected. Our failure to obtain, retain or attract additional customers could prevent us from successfully executing our business plan. We currently work with many leading pharmaceutical companies, including Pfizer, Eli Lilly, Actavis, AstraZeneca, Alcon, Daiichi Sankyo, Novartis, NovoNordisk, Valeant, Shire, and others. Our failure to retain existing customers or expand with new customers could negatively impact our business. We are dependent on a concentrated group of customers. Our revenues are concentrated in approximately 25 customers, primarily large pharmaceutical manufacturers and large advertising agencies. Loss of one ormore of our larger customers could have a significant negative impact on our operating results. Our two largest customers represented 12% and 6% of oursales in 2016, respectively. We may be unable to support our technology to further scale our operations successfully. Our plan is to grow rapidly through further integration of our technology in electronic platforms. Our growth will place significant demands on ourmanagement and technology development, as well as our financial, administrative and other resources. We cannot guarantee that any of the systems,procedures and controls we put in place will be adequate to support the commercialization of our operations. Our operating results will depend substantiallyon the ability of our officers and key employees to manage changing business conditions and to implement and improve our financial, administrative andother resources. If we are unable to respond to and manage changing business conditions, or the scale of our products, services and operations, then thequality of our services, our ability to retain key personnel and our business could be harmed. 6  If we are unable to maintain our contracts with electronic prescription platforms, our business will suffer. We are reliant upon our contracts with leading electronic prescribing platforms, including Allscripts, Dr. First, Quest Diagnostics, Practice Fusion, and others.Such arrangements subject us to a number of risks, including the following: ●our contract partners may experience financial, regulatory or operational difficulties, which may impair their ability to focus on and fulfill theircontact obligations to us;●legal disputes or disagreements, including the ownership of intellectual property, may occur with one or more of our partners and may lead tolengthy and expensive litigation or arbitration;●significant changes in a partner’s business strategy may adversely affect a partner’s willingness or ability to satisfy obligations under any sucharrangement; and●a partner could terminate the partnership arrangement, which could negatively impact our ability to sell our products and achieve revenues. We will need to maintain these relationships as well as diversify them. The inability to do so could adversely impact our business. Our agreements with electronic prescription platforms are subject to audit. Our agreements with our electronic prescription platform partners provide for revenue sharing payments to the platform partners based on the revenue wegenerate through the platform. These payments are subject to audit by our partners, at their cost, and if there is a dispute as to the calculation, we may beliable for additional payments. If an underpayment is determined to be in excess of a certain amount, for example 10%, some agreements would require us topay for the cost of the audit, as well. Developing and implementing new and updated applications, features and services for our portals may be more difficult than expected, may take longerand cost more than expected and may not result in sufficient increases in revenue to justify the costs. We have completed the development and migration of our on-demand, rule based content delivery platform. Attracting and retaining users of our portalsrequires us to continue to improve the technology underlying those portals and to continue to develop new and updated applications, features and servicesfor those portals. If we are unable to do so on a timely basis or if we are unable to implement new applications, features and services without disruption to ourexisting ones, we may lose potential users and clients. The costs of development of these enhancements may negatively impact our ability to achieveprofitability. We rely on a combination of internal development, strategic relationships, licensing and acquisitions to develop our portals and related applications, featuresand services. Our development and/or implementation of new technologies, applications, features and services may cost more than expected, may take longerthan originally expected, may require more testing than originally anticipated and may require the acquisition of additional personnel and other resources.There can be no assurance that the revenue opportunities from any new or updated technologies, applications, features or services will justify the amountsspent. If we are unable to adhere to the regulatory and competitive climate in which we operate, we could be materially and negatively impacted. Do to the labyrinth of regulations in healthcare space, state and federal, as well as political sensitivity of healthcare delivery, our business model could benegatively impacted or fail. The markets in which we operate are competitive, continually evolving and, in some cases, subject to rapid change. ●Our portals face competition from numerous other companies, both in attracting users and in generating revenue from advertisers and sponsors. Wecompete for users with online services and websites that provide savings on medications and healthcare products, including both commercial sitesand not-for-profit sites. We compete for advertisers and sponsors with: health-related web sites; general purpose consumer web sites that offerspecialized health sub-channels; other high-traffic web sites that include both healthcare-related and non-healthcare-related content and services;search engines that provide specialized health search; and advertising networks that aggregate traffic from multiple sites. 7  ●Our healthcare provider portals compete with: providers of healthcare decision-support tools and online health management applications; wellnessand disease management vendors; and health information services and health management offerings of healthcare benefits companies and theiraffiliates. Many of our competitors have greater financial, technical, product development, marketing and other resources than we do. These organizations may bebetter known than we are and have more customers or users than we do. We cannot provide assurance that we will be able to compete successfully againstthese organizations or any alliances they have formed or may form. Since there are no substantial barriers to entry into the markets in which our public portalsparticipate, we expect that competitors will continue to enter these markets. Developments in the healthcare industry could adversely affect our business. Most of our revenue is derived from the healthcare industry and could be affected by changes affecting healthcare spending. We are particularly dependenton pharmaceutical, biotechnology and medical device companies for our advertising and sponsorship revenue. General reductions in expenditures by healthcare industry participants could result from, among other things: ●government regulation or private initiatives that affect the manner in which healthcare providers interact with patients, payers or other healthcareindustry participants, including changes in pricing or means of delivery of healthcare products and services;●government regulation prohibiting the use of coupons by patients covered by federally funded health insurance programs;●consolidation of healthcare industry participants;●reductions in governmental funding for healthcare; and●adverse changes in business or economic conditions affecting healthcare payers or providers, pharmaceutical, biotechnology or medical devicecompanies or other healthcare industry participants. Even if general expenditures by industry participants remain the same or increase, developments in the healthcare industry may result in reduced spending insome or all of the specific market segments that we serve or are planning to serve. For example, use of our products and services could be affected by: ●changes in the design of health insurance plans;●a decrease in the number of new drugs or medical devices coming to market;●a decrease in marketing expenditures by pharmaceutical or medical device companies, including as a result of governmental regulation or privateinitiatives that discourage or prohibit advertising or sponsorship activities by pharmaceutical or medical device companies; and●payor pressure to move to generic brands. In addition, our customers’ expectations regarding pending or potential industry developments may also affect their budgeting processes and spending planswith respect to products and services of the types we provide. The healthcare industry has changed significantly in recent years and we expect that significant changes will continue to occur. However, the timing andimpact of developments in the healthcare industry are difficult to predict. We cannot assure you that the markets for our products and services will continueto exist at current levels or that we will have adequate technical, financial and marketing resources to react to changes in those markets. Because we are embroiled in various lawsuits from time to time with uncertain consequences, the outcome of potential judgments may negatively affect ourfinancial condition and results of operations. We are currently involved in litigation and other disputes, as described in Part I, Item 3 of this annual report. As we continue to grow, we can expect to haveto deal with lawsuits that affect our business. Lawsuits are uncertain and involve a substantial degree of risk. If we are unable to successfully prosecute ordefend these actions, our financial condition and results of operations could suffer. 8  Our success is dependent in part on obtaining, maintaining and enforcing our proprietary rights and our ability to avoid infringing on the proprietaryrights of others. We seek patent protection for those inventions and technologies for which we believe such protection is suitable and is likely to provide a competitiveadvantage to us. Because patent applications in the United States are maintained in secrecy until either the patent application is published or a patent isissued, we may not be aware of third-party patents, patent applications and other intellectual property relevant to our products that may block our use of ourintellectual property or may be used in third-party products that compete with our products and processes. In the event a competitor or other partysuccessfully challenges our products, processes, patents or licenses or claims that we have infringed upon their intellectual property, we could incursubstantial litigation costs defending against such claims, be required to pay royalties, license fees or other damages or be barred from using the intellectualproperty at issue, any of which could have a material adverse effect on our business, operating results and financial condition. We also rely substantially on trade secrets, proprietary technology, nondisclosure and other contractual agreements, and technical measures to protect ourtechnology, application, design, and manufacturing know-how, and work actively to foster continuing technological innovation to maintain and protect ourcompetitive position. We cannot assure you that steps taken by us to protect our intellectual property and other contractual agreements for our business willbe adequate, that our competitors will not independently develop or patent substantially equivalent or superior technologies or be able to design aroundpatents that we may receive, or that our intellectual property will not be misappropriated. Our business will suffer if our network systems fail or become unavailable. A reduction in the performance, reliability and availability of our network infrastructure would harm our ability to distribute our products to our users, as wellas our reputation and ability to attract and retain customers. Our systems and operations could be damaged or interrupted by fire, flood, power loss,telecommunications failure, Internet breakdown, earthquake and similar events. Our systems could also be subject to viruses, break-ins, sabotage, acts ofterrorism, acts of vandalism, hacking, cyber-terrorism and similar misconduct. We might not carry adequate business interruption insurance to compensate usfor losses that may occur from a system outage. Any system error or failure that causes interruption in availability of our product or an increase in responsetime could result in a loss of potential customers, which could have a material adverse effect on our business, financial condition and results of operations. Ifwe suffer sustained or repeated interruptions, then our products and services could be less attractive to our users and our business would be materially harmed. If we are unable to manage growth, our operations could be adversely affected. Our progress is expected to require the full utilization of our management, financial and other resources. Our ability to manage growth effectively will dependon our ability to improve and expand operations, including our financial and management information systems, and to recruit, train and manage personnel.There can be no absolute assurance that management will be able to manage growth effectively. If we do not properly manage the growth of our business, we may experience significant strains on our management and operations and disruptions in ourbusiness. Various risks arise when companies and industries grow quickly. If our business or industry grows too quickly, our ability to meet customer demandin a timely and efficient manner could be challenged. We may also experience development delays as we seek to meet increased demand for our products.Our failure to properly manage the growth that we or our industry might experience could negatively impact our ability to execute on our operating plan and,accordingly, could have an adverse impact on our business, our cash flow and results of operations, and our reputation with our current or potentialcustomers. 9  Our business is subject to changing regulation of corporate governance and public disclosure. Because our common stock is publicly traded, we are subject to certain rules and regulations of federal and state entities charged with the protection ofinvestors and the oversight of companies whose securities are publicly traded. These entities have continued to develop additional regulations andrequirements in response to laws enacted by Congress, most notably the Sarbanes-Oxley Act of 2002. Complying with these new regulations has resulted in,and is likely to continue to result in, increased general & administrative costs and a diversion of management time and attention from revenue generating andother business activities to compliance activities. Risks Relating to Our Securities If a market for our common stock does not develop, shareholders may be unable to sell their shares. Our common stock is quoted under the symbol “OPRX” on the OTCQB operated by OTC Markets Group, Inc., an electronic inter-dealer quotation mediumfor equity securities. We do not currently have an active trading market. There can be no assurance that an active and liquid trading market will develop or, ifdeveloped, that it will be sustained. Our securities are very thinly traded. Accordingly, it may be difficult to sell shares of our common stock without significantly depressing the value of thestock. Unless we are successful in developing continued investor interest in our stock, sales of our stock could continue to result in major fluctuations in theprice of the stock. The market price of our common stock is likely to be highly volatile and could fluctuate widely in price in response to various factors, many of which arebeyond our control. Our stock price is subject to a number of factors, including: ●technological innovations or new products and services by us or our competitors;●government regulation of our products and services;●the establishment of partnerships with other healthcare companies;●intellectual property disputes;●additions or departures of key personnel;●sales of our common stock;●our ability to integrate operations, technology, products and services;●our ability to execute our business plan;●operating results below or exceeding expectations;●whether we achieve profits or not;●loss or addition of any strategic relationship;●industry developments;●economic and other external factors; and●period-to-period fluctuations in our financial results. Our stock price may fluctuate widely as a result of any of the above. In addition, the securities markets have from time to time experienced significant priceand volume fluctuations that are unrelated to the operating performance of particular companies. These market fluctuations may also materially andadversely affect the market price of our common stock. Because we are subject to the “Penny Stock” rules, the level of trading activity in our stock may be reduced. The Securities and Exchange Commission has adopted regulations which generally define "penny stock" to be any listed, trading equity security that has amarket price less than $5.00 per share or an exercise price of less than $5.00 per share, subject to certain exemptions. The penny stock rules require a broker-dealer, prior to a transaction in a penny stock not otherwise exempt from the rules, to deliver a standardized risk disclosure document that providesinformation about penny stocks and the risks in the penny stock market. The broker-dealer must also provide the customer with current bid and offerquotations for the penny stock, the compensation of the broker-dealer and its salesperson in the transaction, and monthly account statements showing themarket value of each penny stock held in the customer’s account. In addition, the penny stock rules generally require that prior to a transaction in a pennystock, the broker-dealer make a special written determination that the penny stock is a suitable investment for the purchaser and receive the purchaser’swritten agreement to the transaction. These disclosure requirements may have the effect of reducing the level of trading activity in the secondary market for astock that becomes subject to the penny stock rules which may increase the difficulty Purchasers may experience in attempting to liquidate such securities. 10  We do not expect to pay dividends in the foreseeable future. Any return on investment may be limited to the value of our common stock. We do not anticipate paying cash dividends on our common stock in the foreseeable future. The payment of dividends on our common stock will depend onearnings, financial condition and other business and economic factors affecting it at such time as the board of directors may consider relevant. If we do notpay dividends, our common stock may be less valuable because a return on your investment will occur only if our stock price appreciates. Provisions in the Nevada Revised Statutes and our Bylaws could make it very difficult for an investor to bring any legal actions against our directors orofficers for violations of their fiduciary duties or could require us to pay any amounts incurred by our directors or officers in any such actions. Members of our board of directors and our officers will have no liability for breaches of their fiduciary duty of care as a director or officer, except in limitedcircumstances, pursuant to provisions in the Nevada Revised Statutes and our Bylaws as authorized by the Nevada Revised Statutes. Specifically, Section78.138 of the Nevada Revised Statutes provides that a director or officer is not individually liable to the company or its shareholders or creditors for anydamages as a result of any act or failure to act in his or her capacity as a director or officer unless it is proven that (1) the director’s or officer’s act or failure toact constituted a breach of his or her fiduciary duties as a director or officer and (2) his or her breach of those duties involved intentional misconduct, fraud ora knowing violation of law. This provision is intended to afford directors and officers protection against and to limit their potential liability for monetarydamages resulting from suits alleging a breach of the duty of care by a director or officer. Accordingly, you may be unable to prevail in a legal action againstour directors or officers even if they have breached their fiduciary duty of care. In addition, our Bylaws allow us to indemnify our directors and officers fromand against any and all costs, charges and expenses resulting from their acting in such capacities with us. This means that if you were able to enforce anaction against our directors or officers, in all likelihood, we would be required to pay any expenses they incurred in defending the lawsuit and any judgmentor settlement they otherwise would be required to pay. Accordingly, our indemnification obligations could divert needed financial resources and mayadversely affect our business, financial condition, results of operations and cash flows, and adversely affect prevailing market prices for our common stock. Item 2. Properties Currently, we do not own any real estate. Our principal executive offices are located at 400 Water Street, Suite 200, Rochester, Michigan 48307. We initially signed the lease for our current office space on December 1, 2011. That lease expired on November 30, 2016 and we signed a new lease coveringthe same space. The new lease is a three-year lease beginning December 1, 2016, with options for up to an additional 6 years. The rent is payable monthly atrates of $6,232, $6,308, and $6,384 per month for years 1, 2, and 3 of the lease, respectively. The monthly rates for the option years range from $6,384 permonth to $6,688 per month for the option years 4 through 9 of the lease. If we fail to exercise our option for option years 4 and 5, a lease termination paymentof $7,300 will be due at the end of the initial 3-year term. We also have a short-term lease on shared office space in Cambridge Massachusetts expiring May 31, 2017. The lease is a nine-month lease calling for sixmonthly payments of $2,997 and three free months. We believe that our properties are adequate for our current needs, but growth potential may require larger facilities due to anticipated addition of personnel.We do not have any policies regarding investments in real estate, securities or other forms of property. Item 3. Legal Proceedings In March, 2015, we initiated litigation in federal court against LDM Group, LLC and PDR Network, LLC. That action was dismissed and later re-initiated inMissouri state court. Our claims are related to the breach by LDM of the settlement agreement signed February 28, 2014 to resolve previous litigation withLDM. Following execution of that agreement, LDM failed to live up to its obligations under that settlement agreement including, but not limited to, notallowing us to distribute our eCoupon programs in the LDM network, not allowing us to distribute the LDM patient education programs, and not providingother information on a timely basis or at all as required under the settlement agreement. In addition, our claims include PDR’s breach of the Master ServicesAgreement requiring PDR’s exclusive use of our eCoupon solution. We assert that PDR’s acquisition of LDM and the use of the LDM network to distributecoupons by PDR violates the agreement between the parties. We are also claiming that LDM and PDR entered a civil conspiracy to violate their respectiveagreements with us. We are seeking enforcement of the agreements and we are seeking damages in an amount at least equal to the amounts paid to date toLDM under the settlement agreement, which is in excess of $1.0 million, as well as damages for lost income and business value. The parties are currently in the discovery process. Item 4. Mine Safety Disclosures Not applicable. 11  PART II Item 5. Market for Registrant’s Common Equity and Related Stockholder Matters and Issuer Purchases of Equity Securities Market Information Our common stock is quoted under the symbol “OPRX” on the OTCQB operated by OTC Markets Group, Inc. Only a limited market exists for our securities.There is no assurance that a regular trading market will develop, or if developed, that it will be sustained. Therefore, a shareholder may be unable to resell hissecurities in our company. The following tables set forth the range of high and low bid information for our common stock for the each of the periods indicated as reported by theOTCQB. These quotations reflect inter-dealer prices, without retail mark-up, mark-down or commission and may not necessarily represent actual transactions. Fiscal Year Ending December 31, 2015Quarter Ended High $ Low $ December 31, 2015 1.34 1.10 September 30, 2015 1.28 0.76 June 30, 2015 1.73 0.81 March 31, 2015 1.59 0.98 Fiscal Year Ending December 31, 2016Quarter Ended High $ Low $ December 31, 2016 1.14 0.71 September 30, 2016 1.20 1.00 June 30, 2016 1.20 0.95 March 31, 2016 1.24 0.89 Quarter Ended March 31, 2017 (through March 1, 2017) 0.83 $0.66 On March 1, 2017, the last sales price per share of our common stock was $0.70. Penny Stock The SEC has adopted rules that regulate broker-dealer practices in connection with transactions in penny stocks. Penny stocks are generally equity securitieswith a market price of less than $5.00, other than securities registered on certain national securities exchanges or quoted on the NASDAQ system, providedthat current price and volume information with respect to transactions in such securities is provided by the exchange or system. The penny stock rules requirea broker-dealer, prior to a transaction in a penny stock, to deliver a standardized risk disclosure document prepared by the SEC, that: (a) contains adescription of the nature and level of risk in the market for penny stocks in both public offerings and secondary trading; (b) contains a description of thebroker's or dealer's duties to the customer and of the rights and remedies available to the customer with respect to a violation of such duties or otherrequirements of the securities laws; (c) contains a brief, clear, narrative description of a dealer market, including bid and ask prices for penny stocks and thesignificance of the spread between the bid and ask price; (d) contains a toll-free telephone number for inquiries on disciplinary actions; (e) defines significantterms in the disclosure document or in the conduct of trading in penny stocks; and (f) contains such other information and is in such form, includinglanguage, type size and format, as the SEC shall require by rule or regulation. The broker-dealer also must provide, prior to effecting any transaction in a penny stock, the customer with (a) bid and offer quotations for the penny stock;(b) the compensation of the broker-dealer and its salesperson in the transaction; (c) the number of shares to which such bid and ask prices apply, or othercomparable information relating to the depth and liquidity of the market for such stock; and (d) a monthly account statement showing the market value ofeach penny stock held in the customer's account. 12  In addition, the penny stock rules require that prior to a transaction in a penny stock not otherwise exempt from those rules, the broker-dealer must make aspecial written determination that the penny stock is a suitable investment for the purchaser and receive the purchaser's written acknowledgment of thereceipt of a risk disclosure statement, a written agreement as to transactions involving penny stocks, and a signed and dated copy of a written suitabilitystatement. These disclosure requirements may have the effect of reducing the trading activity for our common stock. Therefore, stockholders may have difficulty sellingour securities. Holders of Our Common Stock As of March 1, 2017, we had 29,718,867 shares of our common stock issued and outstanding, held by approximately 325 shareholders of record at ourtransfer agent, with approximately 1,000 additional shareholders holding our shares in street name. Dividends We currently intend to retain future earnings for the operation of our business. We have never declared or paid cash dividends on our common stock, and wedo not anticipate paying any cash dividends in the foreseeable future. In the event that a dividend is declared, common stockholders on the record date are entitled to share ratably in any dividends that may be declared from timeto time on the common stock by our board of directors from funds legally available. There are no restrictions in our articles of incorporation or bylaws that restrict us from declaring dividends. The Nevada Revised Statutes, however, doprohibit us from declaring dividends where, after giving effect to the distribution of the dividend: 1.We would not be able to pay our debts as they become due in the usual course of business; or 2.Our total assets would be less than the sum of our total liabilities, plus the amount that would be needed to satisfy the rights of shareholders whohave preferential rights superior to those receiving the distribution. Securities Authorized for Issuance under Equity Compensation Plans On June 13, 2013, our Board of Directors adopted the 2013 Equity Incentive Plan (the “Plan”). The purpose of the Plan is to attract and retain the bestavailable personnel for positions of substantial responsibility with us, to provide additional incentive to employees, directors and consultants, and topromote our success. Under the initial Plan, we were able to issue up to an aggregate total of 1,500,000 incentive or non-qualified options to purchase ourcommon stock, or stock awards. In March, 2016, the Board expanded the number of shares issuable under the plan to 4,000,000. 13  Equity Compensation Plans as of December 31, 2016 Equity CompensationPlans Not Approved bythe Shareholders Number ofSecurities tobe issued uponexerciseof outstandingoptions Weighted-averageexercise priceofoutstandingoptions Number ofSecuritiesremainingavailablefor futureissuance underequitycompensationplans (a) (b) (c) 2013 Equity Compensation Plan 3,095,000 $1.12 855,000 Other Equity Compensation (includes options and warrants) 2,069,583 $1.67 – Total 5,164,583 $1.41 855,000 Recent Sales of Unregistered Securities The information set forth below relates to our issuances of securities without registration under the Securities Act of 1933 during the reporting period whichwere not previously included in a Quarterly Report on Form 10-Q or Current Report on Form 8-K. In December, 2016, we issued 12,500 shares of restricted common stock to our outside Directors as part of our director compensation package for servicesrendered in the fourth quarter of 2015. In 2016, we issued 236,213 shares of restricted common stock in connection with the cashless exercise of stock options. These securities were issued pursuant to Section 4(2) of the Securities Act and/or Rule 506 promulgated thereunder. The holders represented their intention toacquire the securities for investment only and not with a view towards distribution. The investors were given adequate information about us to make aninformed investment decision. We did not engage in any general solicitation or advertising. We directed our transfer agent to issue the stock certificates withthe appropriate restrictive legend affixed to the restricted stock. Item 7. Management’s Discussion and Analysis of Financial Condition and Results of Operations Forward-Looking Statements Certain statements, other than purely historical information, including estimates, projections, statements relating to our business plans, objectives, andexpected operating results, and the assumptions upon which those statements are based, are “forward-looking statements.” These forward-looking statementsgenerally are identified by the words “believes,” “project,” “expects,” “anticipates,” “estimates,” “intends,” “strategy,” “plan,” “may,” “will,” “would,” “willbe,” “will continue,” “will likely result,” and similar expressions. Forward-looking statements are based on current expectations and assumptions that aresubject to risks and uncertainties which may cause actual results to differ materially from the forward-looking statements. Our ability to predict results or theactual effect of future plans or strategies is inherently uncertain. Factors which could have a material adverse effect on our operations and future prospects ona consolidated basis include, but are not limited to: changes in economic conditions, legislative/regulatory changes, availability of capital, interest rates,competition, and generally accepted accounting principles. These risks and uncertainties should also be considered in evaluating forward-looking statementsand undue reliance should not be placed on such statements. 14  Results of Operations for the Years Ended December 31, 2016 and 2015 Revenues Our total revenue reported for the year ended December 31, 2016 was approximately $7.75 million, an increase of 7% from the year ended December 31,2015. We expect revenue growth to accelerate in 2017 as a result of the foundations laid in 2016. Because the pharmaceutical industry is dominated by large companies with multiple brands, our revenue is concentrated in a relatively small number ofcompanies. We have approximately 25 pharmaceutical companies as customers. We have been focusing our efforts on expanding both our customer base andour product offerings and are becoming less dependent on any one customer. In 2015, approximately 32% of our revenues came from our two largestcustomers, while in 2016 only approximately 18% of our revenues came from those same two customers. Cost of Sales Our total cost of sales, composed primarily of revenue share expense, decreased in the year ended December 31, 2016, from the year ended December 31,2015 primarily as a result of the product mix. In addition, revenue share expense as a percentage of revenue in 2016 decreased from 2015 from approximately50% in the year ended December 31, 2015 to approximately 44% in the year ended December 31, 2016. This decrease in revenue share expense as a percentage of revenue results from a combination of factors, including product mix whereby a larger percentageof overall revenues are not subject to revenue share. In addition, we have signed revenue share agreements with new partners that have the effect of loweringthe revenue share percentage, as well as amending certain existing agreements to obtain the same result. We expect revenue share expense as a percentage ofrevenue in 2017 to continue at levels similar to that of 2016, or even increase slightly, because we expect growth to accelerate in those revenue categoriessubject to revenue share expense. However, we expect to continue our efforts to lower the revenue share percentages in our agreements. In addition, ourcomarketing agreement with WPP requires us to pay revenue share to WPP agencies on new brands secured for us by those agencies. If we successfullyexpand revenue through the WPP relationship, our revenue share percentage will increase. Operating Expenses Operating expenses increased to approximately $5.9 million for the year ended December 31, 2016 from approximately $4.2 million for the year endedDecember 31, 2015, an increase of approximately 41%. The detail by major category is reflected in the table below. Years Ended December 31 2016 2015 Salaries, Wages, & Benefits $2,919,809 $1,788,471 Professional Fees 576,995 397,566 Board Compensation 50,000 50,000 Investor Relations 127,082 80,618 Consultants 213,535 66,985 Advertising and Promotion 296,997 47,927 Depreciation and Amortization 235,284 333,950 Development and Maintenance 398,396 540,371 Office, Facility, and other 214,776 151,826 Travel 279,403 157,062 Subtotal 5,312,277 3,614,776 Stock-based compensation 559,301 581,106 Lawsuit settlement 50,000 - Total Operating Expense $5,921,578 $4,195,882 15  The main reasons for the overall increase in operating expenses in 2016 was our focus on staffing and scaling our company to focus on, and be able tosupport, accelerated revenue growth. Within the operating expenses, there were a variety of increases, the largest of which was in salaries, wages and benefits as a result of additional staff in 2016,including related benefits. During 2016, we hired a new CEO, a senior VP of strategy and development, two new VPs of sales, as well as additional supportingpositons. Incentive compensation also increased. While bonuses for executive officers in 2016 were similar to, or lower than in 2015, we expanded ourincentive compensation programs to cover all staff. We expect compensation expense to increase in 2017 as both the result of the full year impact of 2016additions, as well as new hires in 2017 to support the expected accelerated revenue growth as it materializes. However, we expect the increase incompensation expense in 2017 to be less than the increase in 2016. Professional fees increased as a result of the litigation in process, primarily related to the PDR/LDM lawsuit. We expect a continued similar level ofprofessional fees in 2017 as a result of the ongoing level of activity on our litigation. Advertising and promotion increased as a result of our efforts inrebranding of our company, including updating our marketing materials and website. Since much of that was a one-time cost, we expect advertising andpromotion costs to decrease in 2017, however, we still plan an increased focus on marketing as compared with years prior to 2016. Development and maintenance of our technology in 2016 decreased from the 2015 level because 2015 included a $250,000 development payment toAllscripts for integration into the Allscripts Touchworks platform. Leaving that payment aside, development and maintenance increased by about 33% as aresult of the expansion of our system capacity and capabilities and the move to a more robust Oracle database late in 2015. We expect development andmaintenance to increase in 2017 as we continue to expand or product line and capabilities. Depreciation and amortization decreased in 2016 from the 2015levels because the initial software development capitalized in early years became fully depreciated in 2015. Other increases in operating expenses generallyincreased as a result of the increased staffing levels. Net Loss We finished the year ended December 31, 2016 with a loss of approximately $1.5 million, as compared to a loss of approximately $600,000 during the yearended December 31, 2015. The reasons for specific components are discussed above. Overall, we had an increase in revenue and resulting gross margin offsetby increased operating expenses to support future growth. In addition, the loss in both periods included significant noncash items. We had approximately$600,000 of stock based compensation in both years and approximately $235,000 of depreciation in 2016 and approximately $235,000 in 2015. 16  Quarterly Financial Information Following is our quarterly operating results for 2016 for information purposes. First Second Third Fourth Total Quarter Quarter Quarter Quarter Year Revenues $1,759,528 $1,913,299 $1,786,137 $2,292,498 $7,751,462 Revenue Share Expense 892,793 922,832 723,396 872,375 3,411,396 Gross Profit 866,735 990,467 1,062,741 1,420,123 4,340,066 Operating Expenses 1,228,726 1,592,982 1,311,959 1,787,911 5,921,578 Income (Loss) from Operations (361,991) (602,515) (249,218) (367,788) (1,581,512) Other income 10,076 10,582 6,633 15,018 42,309 Loss before Taxes (351,915) (591,933) (242,585) (352,770) (1,539,203) Provision for Taxes -0- -0- -0- -0- -0- Net Income (Loss) (351,915) (591,933) (242,585) (352,770) (1,539,203) Loss per share Basic and Diluted (0.01) (0.02) (0.01) (0.01) (0.05) Liquidity and Capital Resources As of December 31, 2016, we had total current assets of approximately $10.2 million, compared with current liabilities of approximately $3.7 million,resulting in working capital of approximately $6.5 million and a current ratio of approximately 2.8 to 1. This compares with the working capital balance ofapproximately $7.7 million and the current ratio of 3.3 to 1 at December 31, 2015. This decrease in working capital, as discussed in more detail below, isprimarily the result of the payout to our previous CEO as well as cash used in investing activities. Our cash flow for the year ended December 31, 2016 was negatively impacted by a one-time payment of $720,415 to our previous CEO in lieu of issuance ofapproximately 595,000 common shares due to him from previous years. This payment impacts two sections of the statement of cash flows. As discussed inmore detail below, a portion of these shares were reflected in accounts payable and payment of that portion affects cash flow from operations. The remainingportion was reflected in stock payable in the equity section and affects cash used in financing activities. Following is a table with summary data from the consolidated statement of cash flows for the year ended December 31, 2016, as presented and after removingthe effect of this payment. As presented Adjusted toremove effectof one-timepayment Net cash used in operating activities $(465,965) $(102,965)Net cash used in investing activities (349,538) (349,538)Net cash used in financing activities (357,415) - Net decrease in cash and cash equivalents $(1,172,918) $(452.503) 17  Our operating activities used approximately $465,000 in the year ended December 31, 2016 as comparted with approximately $500,000 provided byoperating activities in the year ended December 31, 2015. The majority of the cash used in operations in 2016 related to a payment to our previous CEO. Wehad an accounts payable recorded at $570,000 to the previous CEO payable in 300,000 shares of common stock. We paid $363,000 in full settlement of theliability in cash in lieu of issuing shares. The difference between the amount paid and the amount recorded was charged to additional paid in capital. We used approximately $350,000 in investing activities in the year ended December 31, 2016 compared with about $100,000 in the year ended December31, 2015. These investment activities relate to improvements being implemented in our software platform, protection and expansion of our patent portfolio,and upgrade of our office facilities and computers. These items represent important components of our business strategy moving forward. Financing activities provided approximately $4.3 million in the year ended December 31, 2015, resulting from the strategic investment of approximately$4.7 million by WPP, net of costs associated with the investment. Financing activities used approximately $357,000 during the year ended December 31,2016. This results from the previously mentioned payment to our previous CEO. In addition to the accounts payable related party, we also owed shares forprevious stock grants. A total payment of approximately $720,000 was made to the previous CEO in 2016, with $363,000 affecting cash flow from operationsand $357,000 reflected as cash flow from financing activities. With our cash on hand, we have sufficient cash to operate our business for more than the nexttwelve months and we do not anticipate the need to raise additional equity for operating purposes. Off Balance Sheet Arrangements As of December 31, 2016, there were no off balance sheet arrangements. Critical Accounting Policies A “critical accounting policy” is one which is both important to the portrayal of a company’s financial condition and results, and requires management’smost difficult, subjective or complex judgments, often as a result of the need to make estimates about the effect of matters that are inherently uncertain. Our accounting policies are discussed in detail in the footnotes to our financial statements included in this Annual Report on Form 10-K for the year endedDecember 31, 2016, however we consider our critical accounting policies to be those related to determining the amount of revenue to be billed, the timing ofrevenue recognition, calculation of revenue share expense, stock-based compensation, capitalization and related amortization of intangible assets, andimpairment of assets. Recently Issued Accounting Pronouncements We do not expect the adoption of recently issued accounting pronouncements to have a significant impact on our results of operation, financial position orcash flow. 18  Item 8. Financial Statements and Supplementary Data Index to Financial Statements Required by Article 8 of Regulation S-X: Audited Financial Statements: F-1Report of Independent Registered Public Accounting Firm; F-2Consolidated Balance Sheets as of December 31, 2016 and 2015; F-3Consolidated Statements of Operations for the years ended December 31, 2016 and 2015; F-4Consolidated Statement of Stockholders’ Equity for the year ended December 31, 2015; F-5Consolidated Statement of Stockholders’ Equity for the year ended December 31, 2016; F-6Consolidated Statements of Cash Flows for the years ended December 31, 2016 and 2015; and F-7Notes to Consolidated Financial Statements 19  KLJ & Associates, LLP5201 Eden Ave.Suite 300Edina, MN 55436Office: 630-277-2330Fax: 763-592-8238 REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM Board of DirectorsOptimizeRx CorporationRochester, MI To Whom It May Concern: We have audited the accompanying consolidated balance sheets of OptimizeRx Corporation as of December 31, 2016 and 2015, and the related consolidatedstatements of operations, shareholders' equity (deficit), and cash flows for the years then ended. These consolidated financial statements are the responsibilityof the Company's management. Our responsibility is to express an opinion on these consolidated financial statements based on our audits. We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require thatwe plan and perform the audit to obtain reasonable assurance about whether the consolidated financial statements are free of material misstatement. TheCompany is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. Our audits included considerationof internal control over financial reporting as a basis for designing audit procedures that are appropriate in the circumstances, but not for the purpose ofexpressing an opinion on the effectiveness of the Company’s internal control over financial reporting. Accordingly, we express no such opinion. An auditalso includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the accounting principlesused and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide areasonable basis for our opinion. In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial position of OptimizeRxCorporation as of December 31, 2016 and 2015 and the results of their operations and their cash flows for years ended December 31, 2016 and 2015, inconformity with U.S. generally accepted accounting principles. Sincerely, /s/ KLJ & Associates, LLP KLJ & Associates, LLP Edina, MN March 8, 2017 F-1  OPTIMIZERx CORPORATIONConsolidated Balance Sheets as ofDecember 31, 2016 and 2015 December 31, December 31, 2016 2015 ASSETS Current Assets Cash and cash equivalents $7,034,647 $8,207,565 Accounts receivable 3,060,396 2,847,450 Prepaid expenses 80,820 70,623 Total Current Assets 10,175,863 11,125,638 Property and equipment, net 173,649 10,239 Other Assets Patent rights, net 772,394 832,884 Web development costs, net 351,804 340,470 Security deposit 5,049 5,049 Total Other Assets 1,129,247 1,178,403 TOTAL ASSETS $11,478,759 $12,314,280 LIABILITIES AND STOCKHOLDERS' EQUITY Current Liabilities Accounts payable - trade $369,214 $212,191 Accounts payable - related party - 570,000 Accrued expenses 288,268 6,983 Revenue share payable 2,622,517 2,355,608 Deferred revenue 386,581 227,002 Total Liabilities 3,666,580 3,371,784 Stockholders' Equity Preferred stock, $.001 par value, 10,000,000 shares authorized, no issued and outstanding at December 31, 2016 and2015, - - Common stock, $.001 par value, 500,000,000 shares authorized, 29,718,867 and 29,030,925 shares issued andoutstanding at December 31, 2016 and 2015, respectively 29,719 29,031 Stock warrants 2,294,416 2,329,508 Additional paid-in-capital 33,747,137 32,185,499 Stock Payable - 1,132,148 Deferred stock compensation - (13,800)Accumulated deficit (28,259,093) (26,719,890)Total Stockholders' Equity 7,812,179 8,942,496 TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY $11,478,759 $12,314,280 The accompanying notes are an integral part of these financial statements. F-2  OPTIMIZERx CORPORATIONConsolidated Statements of Operations for the YearsEnded December 31, 2016 and 2015 For the For the year ended year ended December 31, December 31, 2016 2015 NET REVENUE $7,751,462 $7,220,678 REVENUE SHARE EXPENSE 3,411,396 3,622,203 GROSS MARGIN 4,340,066 3,598,475 EXPENSES Operating expenses Stock-based compensation 559,301 581,106 Depreciation and amortization 235,284 333,950 Lawsuit settlement 50,000 - Other operating expenses 5,076,993 3,280,826 Total Operating expenses 5,921,578 4,195,882 LOSS FROM OPERATIONS (1,581,512) (597,407)OTHER INCOME Interest income 42,309 2,267 Interest expense - - TOTAL OTHER INCOME 42,309 2,267 LOSS BEFORE PROVISION FOR INCOME TAXES (1,539,203) (595,140)PROVISION FOR INCOME TAXES - - NET LOSS $(1,539,203) $(595,140)WEIGHTED AVERAGE NUMBER OF SHARES OUTSTANDING: BASIC 29,707,918 24,562,438 NET LOSS PER SHARE: BASIC (no separate per share amount shown for diluted because loss is antidilutive) $(0.05) $(0.02) The accompanying notes are an integral part of these financial statements. F-3  OPTIMIZERx CORPORATIONConsolidated Statement of Stockholders’ Equity for the YearEnded December 31, 2015 PreferredStock Preferred Stock Common Stock Common Stock Stock AdditionalPaid-in Stock Deferred Stock Accumulated TotalStockholders’ Shares Amount Shares Amount Warrants Capital Payable Compensation Deficit Equity Balance,December31, 2014 -0- $-0- 22,867,319 $22,867 $2,153,295 $27,595,609 $963,083 $-0- $(26,124,750) $4,610,084 Issuanceof stockoptions toemployees 253,358 253,358 Issuanceofcommonstock: forservices 152,500 153 172,310 (14,688) (97,650) 60,125 forcash 6,011,106 6,011 176,213 4,164,222 4,346,446 Issuestockrights toofficers 183,773 183,773 Expenseconsultingservices 83,850 83,850 Net lossfor theyear (595,140) (595,140)Balance,December31, 2015 -0- $-0- 29,030,925 $29,031 $2,329,508 $32,185,499 $1,132,168 $(13,800) $(26,719,890) $8,942,496 The accompanying notes are an integral part of these financial statements. F-4  OPTIMIZERx CORPORATIONConsolidated Statement of Stockholders’ Equity for the YearEnded December 31, 2016 PreferredStock Preferred Stock Common Stock Common Stock Stock AdditionalPaid-in Stock Deferred Stock Accumulated TotalStockholders’ Shares Amount Shares Amount Warrants Capital Payable Compensation Deficit Equity Balance,December31, 2015 -0- $-0- 29,030,925 $29,031 $2,329,508 $32,185,499 $1,132,168 $(13,800) $(26,719,890) $8,942,496 Issuance ofstockoptions toemployees 384,126 384,126 Issuance ofcommonstock: forservices 50,000 50 51,325 51,375 for cash 384,188 384 449,116 449,500 foroptions 103,754 104 (104) -0- forlitigationsettlement 100,000 100 109,900 110,000 Issue sharesfor stockpayable 50,000 50 94,450 (94,500) -0- Sharespayableredeemedfor cash 437,733 (1,037,648) (599,915)Expirationof Warrants (35,092) 35,092 -0- Expenseconsultingservices 13,800 13,800 Net loss forthe year (1,539,203) (1,539,203)Balance,December31, 2016 -0- $-0- 29,718,867 $29,719 $2,294,416 $33,747,137 $-0- $-0- $(28,259,093) $7,812,179 The accompanying notes are an integral part of these financial statements. F-5  OPTIMIZERx CORPORATIONConsolidated Statements of Cash Flows for the YearsEnded December 31, 2016 and 2015 For the For the year ended year ended December 31, December 31, 2016 2015 CASH FLOWS FROM OPERATING ACTIVITIES: Net loss for the period $(1,539,203) $(595,140)Adjustments to reconcile net loss to net cash provided by operating activities: Depreciation and amortization 235,284 333,950 Loss on disposal of assets -0- 31,731 Stock options issued for services 384,126 253,358 Stock-based compensation 175,175 327,748 Changes in: Accounts receivable (212,946) (747,069)Prepaid expenses (10,197) (42,530)Accounts payable (205,977) 11,819 Revenue share payable 266,909 852,847 Accrued expenses 281,285 (18,476)Deferred revenue 159,579 106,872 NET CASH PROVIDED BY (USED IN) OPERATING ACTIVITIES (465,965) 515,110 CASH FLOWS FROM INVESTING ACTIVITIES: Purchases of property and equipment (178,434) (2,046)Patent rights (7,268) (1,519)Web development costs (163,836) (97,399)NET CASH USED IN INVESTING ACTIVITIES (349,538) (100,964)CASH FLOWS FROM FINANCING ACTIVITIES: Proceeds from issuance of common stock 449,500 4,346,446 Redemption of common and preferred stock (806,915) -0- NET CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES (357,415) 4,346,446 NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS (1,172,918) 4,760,592 CASH AND CASH EQUIVALENTS - BEGINNING OF PERIOD 8,207,565 3,446,973 CASH AND CASH EQUIVALENTS - END OF PERIOD $7,034,647 $8,207,565 SUPPLEMENTAL CASH FLOW INFORMATION: Cash paid for interest $-0- $-0- Cash paid for income taxes $-0- $-0- SUPPLEMENTAL DISCLOSURE OF NONCASH INVESTING AND FINANCING ACTIVITIES: Common stock issued for future services $-0- $-0- The accompanying notes are an integral part of these financial statements. F-6  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 1 – NATURE OF BUSINESS OptimizeRx Corporation is a technology solutions company serving the healthcare industry by aggregating pharma services for the electronic health records(“EHR”) industry. Our objective is to bring better solutions to better healthcare outcomes through connecting patients, physicians and pharmaceuticalmanufacturers through technology. We are a technology solutions provider with a direct to physician solution through our EHR partners. Our platform allowsphysicians to search, print and send available sample trial vouchers and/or co-pay coupons on behalf of their patients. Our solution is integrated into thephysician’s ePrescribing or EHR applications, but can also be a stand-alone desktop application. OptimizeRx solutions provide pharmaceuticalmanufacturers a direct to physician channel for communicating and promoting their products. It allows healthcare providers a means to provide sampling andcoupons without having to physically store samples on site, and it provides better access and affordability to patients. The company was originally formed as Optimizer Systems, LLC in the State of Michigan on January 31, 2006. It converted its form to a corporation onOctober 22, 2007 and changed its name to OptimizeRx Corporation. On April 14, 2008, RFID, Ltd., a Colorado corporation, consummated a reverse mergerby entering into a share exchange agreement with the stockholders of OptimizeRx Corporation, pursuant to which the stockholders of OptimizeRxCorporation exchanged all of the issued and outstanding capital stock of OptimizeRx Corporation for 1,256,958 shares of common stock of RFID, Ltd.,representing 100% of the outstanding capital stock of RFID, Ltd. As of April 30, 2008, RFID’s officers and directors resigned their positions and RFIDchanged its business to OptimizeRx’s business. On April 15, 2008, RFID, Ltd.’s corporate name was changed to OptimizeRx Corporation. On September 4,2008, a migratory merger was completed, thereby changing the state of incorporation from Colorado to Nevada, resulting in the current corporate structure, inwhich OptimizeRx Corporation, a Nevada corporation, is the parent corporation, and OptimizeRx Corporation, a Michigan corporation, is its wholly-ownedsubsidiary (together, "OptimizeRx" and "the Company"). NOTE 2 – SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES Basis of PresentationThe financial statements of the Company have been prepared in accordance with generally accepted accounting principles in the United States of Americaand are presented in US dollars. Accounting BasisThe Company uses the accrual basis of accounting and accounting principles generally accepted in the United States of America (“GAAP” accounting). TheCompany has adopted a December 31 fiscal year-end. Principles of ConsolidationThe financial statements reflect the consolidated results of OptimizeRx Corporation (a Nevada corporation) and its wholly owned subsidiary, OptimizeRxCorporation (a Michigan corporation). All material inter-company transactions have been eliminated in the consolidation. Cash and Cash EquivalentsFor purposes of the accompanying financial statements, the Company considers all highly liquid instruments with an initial maturity of three months or lessto be cash equivalents. F-7  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 2 – SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED) Fair Value of Financial InstrumentsThe fair value of cash, accounts receivable, prepaid expenses, accounts payable, accounts payable – related party, accrued expenses and deferred revenueapproximates the carrying amount of these financial instruments due to their short-term nature. Fair value is defined as the price that would be received upon sale of an asset or paid upon transfer of a liability in an orderly transaction between marketparticipants at the measurement date and in the principal or most advantageous market for that asset or liability. The fair value should be calculated based onassumptions that market participants would use in pricing the asset or liability, not on assumptions specific to the entity. In addition, the fair value ofliabilities should include consideration of non-performance risk including our own credit risk. In addition to defining fair value, the disclosure requirements around fair value establish a fair value hierarchy for valuation inputs, which is expanded. Thehierarchy prioritizes the inputs into three levels based on the extent to which inputs used in measuring fair value are observable in the market. Each fair valuemeasurement is reported in one of the three levels, which is determined by the lowest level input that is significant to the fair value measurement in itsentirety. These levels are: Level 1 – inputs are based upon unadjusted quoted prices for identical instruments traded in active markets. Level 2 – inputs are based upon significant observable inputs other than quoted prices included in Level 1, such as quoted prices for identical or similarinstruments in markets that are not active, and model-based valuation techniques for which all significant assumptions are observable in the market or can becorroborated by observable market data for substantially the full term of the assets or liabilities. Level 3 – inputs are generally unobservable and typically reflect management’s estimates of assumptions that market participants would use in pricing theasset or liability. The fair values are therefore determined using model-based techniques that include option pricing models, discounted cash flow models,and similar techniques. The Company’s stock options and warrants are valued using level 3 inputs. The carrying value of the Company’s financial assets and liabilities, which consist of cash, accounts receivable, prepaid expenses, patent rights, webdevelopment costs, accounts payable, accounts payable – related party, accrued expenses and deferred revenue, are valued using level 1 inputs. TheCompany believes that the recorded values approximate their fair value due to the short maturity of such instruments. Unless otherwise noted, it ismanagement’s opinion that the Company is not exposed to significant interest, exchange or credit risks arising from these financial instruments. Accounts Receivable and Allowance for Doubtful AccountsAccounts receivable are reported at realizable value, net of allowances for doubtful accounts, which is estimated and recorded in the period the relatedrevenue is recorded. The Company has a standardized approach to estimate and review the collectability of its receivables based on a number of factors,including the period they have been outstanding. Historical collection and payer reimbursement experience is an integral part of the estimation processrelated to allowances for doubtful accounts. In addition, the Company regularly assesses the state of its billing operations in order to identify issues, whichmay impact the collectability of these receivables or reserve estimates. Because the Company’s customers are primarily large well-capitalized companies,historically there has been very little bad debt expense. Bad debt expense was $0 for each of the years ended December 31, 2016 and 2015. The allowance fordoubtful accounts was $0 as of both December 31, 2016 and 2015. F-8  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 2 – SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED) Property and EquipmentCapital assets are being depreciated over their estimated useful lives of three to seven years using the straight-line method of depreciation for book purposes. Revenue Recognition and Revenue Share ExpenseRevenue is recognized when it is earned. Revenues are primarily generated from our content delivery activities in which we deliver financial messagingthrough a distribution network of ePrescribers and Electronic Health Record technology providers (channel partners), or from reselling services thatcomplement our business for other of our partners. We recognize setup fees that are required for integrating client offerings and campaigns into our rule-based content delivery system and network uponcompletion of the setup when the client’s campaign is ready to launch within our system. As the messaging is distributed through our platform and networkof channel partners (a transaction), these transactions are recorded and revenue is recognized at the time of distribution. Revenue for transactions can berealized based on a price per distribution, a price per redemption, or as a flat fee over a period of time, depending on the client contract. Additionally, theCompany also recognizes revenue for providing program performance reporting and maintenance, either by the Company directly delivering reports or byproviding access to its online reporting portal that the client can utilize. These fees are charged monthly and recognized as recurring monthly revenue. In some instances, we also resell products and or services that are available through our channel partners on a commission basis, and that are complementaryto our core business and client base. In these instances, net revenue is recognized based on the commission based revenue split that the Company receives. Ininstances where we resell services and have all financial risk and significant operation input and risk, we record the revenue gross. Based on the volume of transactions that are delivered through our channel partner network, we provide a revenue share to compensate the partner for theirpromotion of the campaign. Revenue shares are a negotiated percentage of the transaction fees and can also be specific to special considerations andcampaigns. In addition, we pay revenue share to ConnectiveRx (formerly LDM/PDR) as a result of a 2014 legal settlement in an amount equal to the greaterof 10% of financial messaging distribution revenues generated or $0.37 per financial message distributed. The contractual amount due to our channelpartners is recorded as an expense at the time the eCoupon is distributed. Income TaxesIncome taxes are computed using the asset and liability method. Under the asset and liability method, deferred income tax assets and liabilities aredetermined based on the differences between the financial reporting and tax basis of assets and liabilities and are measured using the currently enacted taxrates and laws. A valuation allowance is provided for the amount of deferred tax assets that, based on available evidence, are not expected to be realized. Use of EstimatesThe preparation of financial statements in conformity with generally accepted accounting principles requires management to make estimates andassumptions that affect the reported amounts of assets and liabilities at the date of the financial statements and the reported amounts of revenues andexpenses during the reporting period. Estimates and assumptions have been made in determining the carrying value of assets, depreciable and amortizablelives of tangible and intangible assets, the carrying value of liabilities, the amount of revenue to be billed, and the timing of revenue recognition and relatedrevenue share expenses. Actual results could differ from these estimates. Concentration of Credit RisksThe Company maintains its cash and cash equivalents in bank deposit accounts, which, at times, may exceed federally insured limits. The Company has notexperienced any losses in such accounts; however, amounts in excess of the federally insured limit may be at risk if the bank experiences financialdifficulties. F-9  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 2 – SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED) Research and DevelopmentThe Company expenses research and development expenses as incurred. Our research efforts are focused on understanding the market dynamics that have thepotential to affect the business and increase revenue in both the short and long term. Our primary goal is to increase revenue by helping patients better affordand access the medicines their doctors prescribe, as well as other healthcare products and services they need. Based on this, the Company continually seeksways to improve its technology to enhance user experiences, and to develop new services and solutions for its customers. Share-based PaymentsThe Company uses the fair value method to account for stock-based compensation. The fair value of the equity instrument is charged directly tocompensation expense and additional paid-in capital over the period during which services are rendered. The fair value of each award is estimated on the dateof each grant. For restricted stock, the fair market value is based on the market value of the stock granted on the date of the grant. For options, it is estimatedusing the Black=Scholes option pricing model that uses the assumptions noted in the following table. Estimated volatilities are based on the historicalvolatility of the Company’s stock over the same period as the expected term of the options. The expected term of options granted represents the period oftime that options granted are expected to be outstanding. The Company uses historical data to estimate option exercise behavior and to determine this term.The risk free rate used is based on the U.S. Treasury yield curve in effect at the time of the grant using a time period equal to the expected option term. TheCompany has never paid dividends and does not expect to pay any dividends in the future. 2016 2015 Expected dividend yield 0% 0%Risk free interest rate 0.86%-1.15% 0.24%-0.93%Expected option term 4.5 years 2.5 - 3.5 years Turnover/forfeiture rate 0% 0%Expected volatility 91% - 99% 67% - 85% The Black-Scholes option valuation model and other existing models were developed for use in estimating the fair value of traded options that have novesting restrictions and are fully transferable. These option valuation models require the input of, and are highly sensitive to, subjective assumptionsincluding the expected stock price volatility. OptimizeRx’s stock options have characteristics significantly different from those of traded options, andchanges in the subjective input assumptions could materially affect the fair value estimate. Loss Per Common and Common Equivalent ShareThe computation of basic earnings per common share is computed using the weighted average number of common shares outstanding during the year. Thecomputation of diluted earnings per common share is based on the weighted average number of shares outstanding during the year plus common stockequivalents, which would arise from the exercise of warrants outstanding using the treasury stock method and the average market price per share during theyear. Options, warrants and convertible preferred stock have not been included in the diluted earnings per share calculation for either year since their effect isanti-dilutive in all years presented. F-10  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 2 – SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED) Impairment of Long-Lived AssetsThe Company continually monitors events and changes in circumstances that could indicate carrying amounts of long-lived assets may not be recoverable.When such events or changes in circumstances are present, the Company assesses the recoverability of long-lived assets by determining whether the carryingvalue of such assets will be recovered through undiscounted expected future cash flows. If the total of the future cash flows is less than the carrying amount ofthose assets, the Company recognizes an impairment loss based on the excess of the carrying amount over the fair value of the assets. Assets to be disposed ofare reported at the lower of the carrying amount or the fair value less costs to sell. Recently Issued Accounting GuidanceThe Company does not expect the adoption of recently issued accounting pronouncements to have a significant impact on the Company’s results ofoperations, financial position or cash flow. NOTE 3 – PREPAID EXPENSES Prepaid expenses consisted of the following as of December 31, 2016 and 2015: 2016 2015 Insurance $43,608 $30,623 Rent 7,212 -0- Legal 30,000 40,000 Total prepaid expenses $80,820 $70,623 NOTE 4 – PROPERTY AND EQUIPMENT The Company owned equipment recorded at cost which consisted of the following as of December 31, 2016 and 2015: 2016 2015 Computer equipment $66,433 $21,565 Furniture and fixtures 132,905 11,088 Subtotal 199,338 32,653 Accumulated depreciation (25,689) (22,414)Property and equipment, net $173,649 $10,239 Depreciation expense was $22,414 and $4,620 for the years ended December 31, 2016 and 2015, respectively. F-11  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 5 – WEB-BASED TECHNOLOGY The Company has capitalized costs in developing its technology, which consisted of the following as of December 31, 2016 and 2015: 2016 2015 OptimizeRx consumer web-based technology $154,133 $154,133 OptimizeRx EHR integrated technology 1,304,230 1,140,394 Subtotal 1,458,363 1,294,527 Accumulated amortization (1,106,559) (954,057)Web-based technology, net $351,804 $340,470 Amortization is recorded using the straight-line method over a period of up to five years. All remaining carrying value at December 31, 2015 and 2016 relatesto the EHR integrated technology. Amortization expense for the technology costs was $152,502 and $261,572 for the years ended December 31, 2016 and2015, respectively. NOTE 6 – PATENT AND TRADEMARKS On April 26, 2010, the Company acquired the technical contributions and assignment of all exclusive rights to and for a key patent from the former CEO ofthe Company in exchange for 300,000 shares of common stock to be granted at the discretion of the seller and 200,000 stock options, valued at $360,000.The shares were valued on the grant date at $570,000 and were recorded as a payable to the related party. The obligation to deliver those shares was redeemedin 2016 for a cash payment of $363,000. The Company has capitalized costs in purchasing and defending its patent, which consisted of the following as of December 31, 2016 and 2015: 2016 2015 Patent rights and intangible assets $930,000 $930,000 Patent defense costs 172,457 172,457 New patents and trademarks 65,738 58,469 Accumulated amortization (395,801) (328,042)Patent rights and intangible assets, net $772,394 $832,884 The Company began amortizing the patent, using the straight-line method over the estimated useful life of 17 years, once it was put into service in July 2010.In 2013, the Company began incurring costs related to defense of the patent. These costs have been capitalized and will be amortized using the straight-linemethod over the remaining useful life of the original patent. Amortization expense was $67,758 for both of the years ended December 31, 2016 and 2015. F-12  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 7 – DEFERRED REVENUE The Company has several signed contracts with customers for the distribution of financial messaging, or other services, which include payment in advance.The payments are not recorded as revenue until the revenue is earned under its revenue recognition policy discussed in Note 2. Deferred revenue was$386,581 and $227,002 as of December 31, 2016 and 2015, respectively. NOTE 8 – RELATED PARTY TRANSACTIONS During the year ended December 31, 2010, the Company acquired the technical contributions and assignment of all exclusive rights to and for a key patentin process at the time from a former CEO in exchange for 300,000 shares of common stock to be granted at the discretion of the seller and 200,000 stockoptions, valued at $360,000, which expired in April 2015. The shares were valued on the grant date at $570,000 and were recorded as a payable to the relatedparty. In 2016 the obligation to issue those shares was redeemed for a payment of $363,000 in cash. During the year ended December 31, 2015, WPP made a strategic investment in the Company and is a shareholder that owns approximately 20% of the sharesof the Company. During 2016, we had billings of $2,613,942 to agencies that are part of the WPP group and recognized revenue of $1,542,411 related to those billings. As ofDecember 31, 2016, we have receivables included in trade receivables on the balance sheet of $1,108,585 from WPP agencies and amounts due to WPPagencies included in revenue share payable of $127,458 as of December 31, 2016. In addition, we purchased of $190,686 from WPP agencies in 2016 andhad amounts owed related to those services of $12,600 in accounts payable at December 31, 2016. During 2015, we had billings of $420,503 to agencies that are part of the WPP group and recognized revenue of $178,855 related to those billings. As ofDecember 31, 2015, we have receivables included in trade receivables on the balance sheet of $381,125 from WPP agencies and amounts due to WPPagencies included in revenue share payable of $37,803 as of December 31, 2015. NOTE 9 – PREFERRED STOCK The Company has 10,000,000 shares of preferred stock, $.001 par value per share, authorized as of December 31, 2016. There were no shares outstanding atany time during the periods covered by these financial statements. NOTE 10 – COMMON STOCK The Company had 500,000,000 shares of common stock, $.001 par value per share, authorized as of December 31, 2016. There were 29,718,867 and29,030,925 shares of common stock issued and outstanding at December 31, 2016 and 2015, respectively. In July 2016, we issued 384,118 shares of common stock to an unrelated party in a private transaction, the proceeds of which were used to redeem shares ofcommon stock payable to an executive officer. The Company has a Director Compensation plan covering its independent non-employee Directors. A total of 50,000 shares were granted and issued in eachof the years ended December 31, 2016 and 2015 in connection with this compensation plan. These shares were valued at $51,375 and $60,125, respectively. The Company issued 100,000 shares of common stock, valued at $110,000, to Shadron Stastney in connection with the settlement of litigation described ingreater detail in Note 16. F-13  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 10 – COMMON STOCK (CONTINUED) The Company issued 103,754 shares of common stock in 2016 in connection with the cashless exercise of stock options granted in prior years that wereabout to expire in 2016. In February, 2015, the Company entered into a capital markets advisory agreement covering a one-year period, which called for 90,000 shares of commonstock to be issued as compensation. These shares were valued at $112,500 and were amortized to expense over the period of service. 45,000 of these shareswere issued in March 2015. The agreement was terminated in July 2015, effective in August, and the remaining 45,000 shares were not issued. The totalexpense recognized was $56,250. In June, 2015, the Company agreed to grant 197,605 fully vested shares of its common stock to two executive officers as bonuses. These shares were notissued at the time, but were recorded as stock payable. The obligation to issue these shares was redeemed for cash in 2016 for a total payment of $232,602. In September, 2015, the Company entered into a new capital markets advisory agreement covering a one-year period, which called for 90,000 shares ofcommon stock to be issued as compensation. The first 45,000 shares were issued in September 2015 and valued at $41,400. These shares were amortized overa six-month period. The agreement was cancelled in February 2016 and the remaining 45,000 shares were not issued. In February 2014, the Company agreed to grant 337,500 shares of common stock, half of which vested immediately and half of which vested in August 2014,to two executive officers as bonuses based on their efforts to recapitalize the Company. Stock-based compensation related to these bonuses of $570,375 wasrecorded during the year ended December 31, 2014. These shares were not issued at the time and were recorded as stock payable. The obligation to issuethese shares was redeemed in 2016 for cash payments of $397,038. Also in 2014, as part of a capital raise, the Company agreed to grant 200,000 shares ofcommon stock to three executive officers. The shares were part of an equity raise and the issuance was recorded as part of equity issuance costs, so no expensewas recorded. In 2016, a total of 150,000 of those shares were redeemed for a cash payment of $177,275 and the remaining 50,000 shares were issued to aformer executive officer. In September, 2015, the Company entered into a securities purchase agreement pursuant to which the Company sold 6,011,106 shares of its common stockfor $0.7875 per share, or gross proceeds of $4,733,746. The shares were issue to a subsidiary of WPP, the world’s largest marketing services company, as partof a strategic investment by WPP. Placement agents in the offering received commissions and expenses of $387,300, or approximately 8.2% of the grossproceeds. The net proceeds received were $4,346,446. Placement agents also received warrants to purchase up to 240,444 shares of our common stock with anexercise price of $0.7875 per share and a term of 5 years. The warrants were valued at $176,213 and have been recorded as equity issuance costs. F-14  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 11 – STOCK OPTIONS The Company sponsors a stock-based incentive compensation plan known as the 2013 Equity Compensation Plan (the “Plan”), which was established by theBoard of Directors of the Company in June 2013. A total of 1,500,000 shares were initially reserved for issuance under the Plan. The Plan was amended in2016 to increase the authorized shares to 4,000,000 shares. A total of 3,095,000 options have been granted and remain outstanding at December 31, 2016. Inaddition, a total of 735,105 restricted shares were granted in 2014 and 2015, but not issued at the time. A total 685,015 of these shares were redeemed for cashin 2016 and 50,000 of these shares were issued in 2016. As of December 31, 2016, the Company has no remaining restricted shares owed. The Company has855,000 shares available to grant under the Plan at December 31, 2016. The Plan allows the Company to grant incentive stock options, non-qualified stock options, stock appreciation right, or restricted stock. The incentive stockoptions are exercisable for up to ten years, at an option price per share not less than the fair market value on the date the option is granted. The incentivestock options are limited to persons who are regular full-time employees of the Company at the date of the grant of the option. Non-qualified options may begranted to any person, including, but not limited to, employees, independent agents, consultants and attorneys, who the Company’s Board or CompensationCommittee believes have contributed, or will contribute, to the success of the Company. Non-qualified options may be issued at option prices of less than fairmarket value on the date of grant and may be exercisable for up to ten years from date of grant. The option vesting schedule for options granted is determinedby the Compensation Committee of the Board of Directors at the time of the grant. The Plan provides for accelerated vesting of unvested options if there is achange in control, as defined in the Plan. Prior to establishment of the Plan, the Board granted options under terms similar to those described in the preceding paragraphs. A total of 25,000 options areoutstanding at December 31, 2016 that were granted prior to the establishment of the 2013 Plan. The compensation cost that has been charged against income related to options for the years ended December 31, 2016 and 2015, was $384,126 and$253,358, respectively. No income tax benefit was recognized in the income statement and no compensation was capitalized in any of the years presented. The Company had the following option activity during the years ended December 31, 2016 and 2015: Number ofOptions Weightedaverageexercise price Outstanding, January 1, 2015 1,307,500 $1.31 Granted - 2015 550,000 1.25 Exercised - 2015 0 0 Expired – 2015 (242,500) (1.68)Balance, December 31, 2015 1,615,000 1.09 Granted – 2016 2,040,000 1.09 Exercised – 2016 (485,000) 0.89 Expired – 2016 (50,000) (1.08)Balance, December 31, 2016 3,120,000 $1.12 F-15  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 12 – WARRANTS The Company has issued warrants to purchase common stock, primarily in connection with capital raising activities. As discussed in Note 10, in 2015, theCompany issued warrants to purchase 240,444 shares of common stock, with an exercise price of $0.7875 per share in connection with the strategicinvestment by WPP. The Company had the following warrants outstanding as of December 31, 2016: Number of Shares Underlying Warrants Exercise Price Expiration Date 1,000,000 $2.25 10/5/2017 804,139 $1.20 3/17/2019 240,444 $0.7875 9/24/2020 The Company had the following warrant activity during the years ended December 31, 2016 and 2015: Number of SharesUnderlyingWarrants Weightedaverageexercise price Outstanding, January 1, 2015 1,854,139 $1.69 Granted 240,444 0.7875 Expired - - Balance, December 31, 2015 2,094,583 1.65 Granted - - Expired (50,000) 0.89 Balance, December 31, 2016 2,044,583 $1.67 NOTE 13 – OPERATING LEASES The Company initially signed the lease for its current office space located in Rochester Michigan on December 1, 2011. That lease expired November 30,2016 and the Company signed a new lease for the same space. The new lease is a three-year lease beginning December 1, 2016, with options for up to anadditional 6 years. The rent is payable monthly at rates of $6,232, $6,308, and $6,384 per month for years 1, 2, and 3 of the lease, respectively. The monthlyrates for the option years range from $6,384 per month to $6,688 per month for the option years 4 through 9 of the lease. If the Company fails to exercise itsoption for option years 4 and 5, a least termination payment of $7,300 will be due at the end of the initial 3-year term. The Company also has a short-term lease on shared office space in Cambridge Massachusetts expiring May 31, 2017. The lease is a nine-month lease callingfor six monthly payments of $2,997 and three free months. Minimum annual rent payments are as follows for the remaining term of the leases: Year ended December 31: 2017 $77,857 2018 75,772 2019 70,224 Total lease commitment $223,853 F-16  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 14 – MAJOR CUSTOMERS The Company had the following major customers that individually accounted for 10% or more of revenue in any one of the years presented: ` 2016 Percentage 2015 Percentage Customer A $899,299 12% $1,409,720 20%Customer B 449,322 6% 958,653 12% Total Revenues $7,751,462 100% 7,220,678 100% NOTE 15 – INCOME TAXES As of December 31, 2016, the Company had net operating loss carry forwards of approximately $9.1 million that expire from 2027 through 2036 that areavailable to offset future taxable income. The Company was formed in 2006 as a limited liability company and changed to a corporation in 2007. Activityprior to incorporation is not reflected in the Company’s corporate tax returns. In the future, the cumulative net operating loss carry-forward for income taxpurposes may differ from the cumulative financial statement loss due to timing differences between book and tax reporting. The provision for Federal income tax consists of the following for the years ended December 31, 2016 and 2015: 2016 2015 Federal income tax benefit attributable to: Current operations $523,000 $202,000 Permanent and Timing Differences (net) 133,000 (218,000)Valuation allowance (656,000) 16,000 Net provision for federal income tax $0 $0 The cumulative tax effect at the expected rate of 34% of significant items comprising our net deferred tax amount is as follows as of December 31, 2016 and2015: 2016 2015 Deferred tax asset attributable to: Net operating loss carryover $3,766,000 $3,110,000 Valuation allowance (3,766,000) (3,110,000)Net deferred tax asset $0 $0 Under certain circumstances issuance of common shares can result in an ownership change under Internal Revenue Code Section 382 which limits theCompany’s ability to utilize carry forwards from prior to the ownership change. Any such ownership change resulting from stock issuances and redemptionscould limit the Company’s ability to utilize any net operating loss carry forwards or credits generated before this change in ownership. These limitations canlimit both the timing of usage of these laws, as well as the loss of the ability to use these net operating losses. It is likely that fundraising activities haveresulted in such an ownership change. F-17  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 16 – COMMITMENTS AND CONTINGENT LIABILITIES Legal The Company is currently involved in the following legal proceedings. Commencing in September 2014, we were a party to a lawsuit involving our prior CEO, Shadron Stastney, in the U.S. District Court in the Eastern District ofMichigan as a result of a dispute related to his separation agreement. On May 27, 2016, we settled the action. For a complete release of claims and dismissalof the action, we agreed to pay Mr. Stastney $50,000 and to issue him 100,000 shares of our common stock. We further agreed to register 133,333 of hisexisting shares with the Securities and Exchange Commission on Form S-1 by June 30, 2016. We have tendered to Mr. Stastney the cash and shares andregistered his shares in fulfillment of our settlement obligations. In March, 2015, we initiated litigation in federal court against LDM Group, LLC and PDR Network, LLC. That action was dismissed and later re-initiated inMissouri state court. Our claims are related to the breach by LDM of the settlement agreement signed February 28, 2014 to resolve previous litigation withLDM. Following execution of that agreement, LDM failed to live up to its obligations under that settlement agreement including, but not limited to, notallowing us to distribute our eCoupon programs in the LDM network, not allowing us to distribute the LDM patient education programs, and not providingother information on a timely basis or at all as required under the settlement agreement. In addition, our claims include PDR’s breach of the Master ServicesAgreement requiring PDR’s exclusive use of our eCoupon solution. We assert that PDR’s acquisition of LDM and the use of the LDM network to distributecoupons by PDR violates the agreement between the parties. We are also claiming that LDM and PDR entered a civil conspiracy to violate their respectiveagreements with us. We are seeking enforcement of the agreements and we are seeking damages in an amount at least equal to the amounts paid to date toLDM under the settlement agreement, which is in excess of $1.0 million, as well as damages for lost income and business value. The parties are currently in the discovery process. Revenue-share contractsThe Company has contacts with various Electronic Health Records systems and ePrescribe platforms, whereby we agree to share a portion of the revenue wegenerate for eCoupons distributed through their networks. These contracts grant audit rights related to the payments to our partners, and in some cases wouldrequire us to pay for the audit if the audit determined there was an underpayment and the underpayment meets certain thresholds, such as 10%. Allscripts AgreementIn 2015, we signed an amendment to our Allscripts agreement whereby we became its exclusive eCoupon supplier and Allscripts agreed to integrate oureCoupon functionality into its Touchworks platform. Under the terms of this agreement, we agreed to pay $900,000 in two installments. The first installmentof $250,000 was due and paid in November 2015. The second installment of $650,000 becomes due when the e-Coupon functionality is launched on awidespread basis in the Touchworks platform, which occurred February 28, 2017. F-18  OPTIMIZERx CORPORATIONNOTES TO THE CONSOLIDATED FINANCIAL STATEMENTSDECEMBER 31, 2016 NOTE 17 – RETIREMENT PLAN The Company sponsors a defined contribution 401(k) profit sharing plan which was adopted in December, 2015, effective in January 2016. Under the termsof the plan, the Company matches 100% of the first 3% of payroll contributed by the employee and 50% of the next 2% of payroll contributed by theemployee to a maximum of 4% of an employee’s payroll. There was no expense under this plan in 2015, as the plan became effective in 2016. There wasexpense of $64,690 recorded in 2016 for company contributions to the plan. NOTE 18 – SUBSEQUENT EVENTS In accordance with ASC 855-10, the Company has analyzed its operations subsequent to December 31, 2016 through the date these financial statements wereissued and has determined that it does not have any material subsequent events to disclose in these financial statements. F-19  Item 9. Changes In and Disagreements with Accountants on Accounting and Financial Disclosure None. Item 9A. Controls and Procedures Evaluation of Disclosure Controls and Procedures As required by Rule 13a-15 under the Securities Exchange Act of 1934, we have carried out an evaluation of the effectiveness of our disclosure controls andprocedures as of the end of the period covered by this annual report, being December 31, 2016. This evaluation was carried out under the supervision of, andwith the participation of, our management, including our Chief Executive Officer and Chief Financial Officer. Disclosure controls and procedures are controls and other procedures that are designed to ensure that information required to be disclosed in our reports filedor submitted under the Securities Exchange Act of 1934 is recorded, processed, summarized and reported, within the time periods specified in the Securitiesand Exchange Commission’s rules and forms. Disclosure controls and procedures include controls and procedures designed to ensure that informationrequired to be disclosed in our company’s reports filed under the Securities Exchange Act of 1934 is accumulated and communicated to management,including our Chief Executive Officer and Chief Financial Officer, to allow timely decisions regarding required disclosure. Based upon that evaluation, we have concluded that our disclosure controls and procedures are not sufficient as of the end of the period covered by thisannual report. We intend to implement additional procedures to improve disclosure controls. Management’s Report on Internal Control over Financial Reporting Our management is responsible for establishing and maintaining adequate internal control over financial reporting (as defined in Rule 13a-15(f) under theSecurities Exchange Act of 1934). Management has assessed the effectiveness of our internal control over financial reporting as of December 31, 2016 basedon criteria established in Internal Control-Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission. As aresult of this assessment, management concluded that, as of December 31, 2016, our internal control over financial reporting was not effective. Ourmanagement identified the following material weaknesses in our internal control over financial reporting, which are indicative of many small companies withsmall staff: (i) inadequate segregation of duties and effective risk assessment; and (ii) inadequate information technology reporting systems to insure thataccurate information is provided for accounting and financial reporting with respect to the requirements and application of both US GAAP and SECguidelines. We have taken steps to enhance and improve the design of our internal control over financial reporting. During the period covered by this annual report onForm 10-K, we have not been able to completely remediate the material weaknesses identified above. To continue to remediate such weaknesses, we plan toimplement the following changes during our fiscal year ending December 31, 2017. We have developed, and will continue to develop, analytical proceduresand reports which help identify potential errors. In addition, we have hired a new person in the finance area in January 2017 and intend to design newprocedures to improve our segregation of duties. We also hired a new director of information technology and we intend to continue to develop improvementsto the reporting systems in our information technology systems. This annual report does not include an attestation report of our registered public accounting firm regarding internal control over financial reporting.Management’s report was not subject to attestation by our registered public accounting firm pursuant to an exemption for non-accelerated filers set forth inSection 989G of the Dodd-Frank Wall Street Reform and Consumer Protection Act. During the most recently completed fiscal quarter, there has been no change in our internal control over financial reporting that has materially affected or isreasonably likely to materially affect, our internal control over financial reporting. 21  Item 9B. Other Information None PART III Item 10. Directors, Executive Officers and Corporate Governance The following information sets forth the names, ages, and positions of our current directors and executive officers. Name Age Positions and Offices HeldWilliam J. Febbo 48 Chief Executive Officer, DirectorBrian Dillon 66 SVP – Product and StrategyTerence J. Hamilton 51 SVP – SalesDouglas P. Baker 60 Chief Financial OfficerDavid A. Harrell 50 Chairman, DirectorGus D. Halas 66 DirectorJack Pinney 60 DirectorLynn Vos 61 DirectorJames Lang 52 Director Set forth below is a brief description of the background and business experience of each of our current executive officers and directors. David A. Harrell Mr. Harrell founded our company in January of 2006 and has been a Director since our inception. He has served as our Chairman since September 20, 2013,and was our Chief Executive Officer from September 20, 2013 through February 21, 2016. Mr. Harrell was the Vice President of Development for MeridianIncorporated from 2003-2005 and, prior to that, had been Vice President of Sales and Marketing since 1999 at Advance Graphic Systems. Mr. Harrell hasspent two decades leading sales, marketing and business development units within the pharmaceutical and national retail industries. Prior to his work atAdvance Graphic Systems, Mr. Harrell served for ten years at SmithKline Beecham, specializing in the managed markets healthcare segment. As part of theIntegrated Health Division, Mr. Harrell was responsible for contracting and achieving regional revenue growth for SmithKline Beecham's four business units:Pharmaceuticals, Consumer Health, Clinical Labs and Diversified Pharmaceutical Services (PBM). During his tenure with SmithKline Beecham, he was arecipient of numerous national awards and served as a member of the Division's Strategic Planning Committee. Mr. Harrell graduated fromOakland University with a Bachelor of Science in Business Administration. Aside from that provided above, Mr. Harrell does not hold and has not held over the past five years any other directorships in any company with a class ofsecurities registered pursuant to Section 12 of the Exchange Act or subject to the requirements of Section 15(d) of the Exchange Act or any companyregistered as an investment company under the Investment Company Act of 1940. Mr. Harrell is qualified to serve on our Board of Directors because of his sales, marketing and business development experience in the pharmaceutical sector. 22  William J. Febbo Mr. Febbo joined our company as Chief Executive Officer on February 22, 2016. Mr. Febbo brings more than 18 years of experience in building andmanaging health services and financial businesses. Before joining our company, Mr. Febbo served as Chairman and Founder of Plexus, LLC, a paymentprocessing business for medical professionals. From 2007 to 2015, he worked with Merriman Holdings, Inc., an investment banking firm. There he served asChief Operating Officer and assisted with capital raises in the tech, biotech, cleantech, consumer and resources industries. From 2013 to 2015, he also workedwith Digital Capital Network, Inc., which operated a transaction platform for institutional and accredited investors. There he served as Chief ExecutiveOfficer and Co-Founder and managed the day-to-day operations of the digital portal for institutional level investments. Prior to Merriman, Mr Febbo wasCEO and co-founder of MedPanel, a provider of market intelligence and communications for the pharmaceutical, biomedical, and medical device industries,which was eventually acquired by MCF Corporation. Aside from that provided above, Mr. Febbo does not hold and has not held over the past five years any other directorships in any company with a class ofsecurities registered pursuant to Section 12 of the Exchange Act or subject to the requirements of Section 15(d) of the Exchange Act or any companyregistered as an investment company under the Investment Company Act of 1940. Mr. Febbo is qualified to serve on our Board of Directors because of his wealth of experience in building and managing health services and financialbusinesses. Terence J. Hamilton Mr. Hamilton joined our company as VP of Sales in February 2008 and became SVP of Sales in 2016. Prior to that, Mr. Hamilton was Manager at MedImmunesince 2005 and was Senior National Account Manager for Glaxo SmithKline pharmaceuticals for 13 years prior to that. Mr. Hamilton has spent the last 19years working in the pharmaceutical and biotech arenas within various sales, marketing and managed markets management positions. He also has held manypositions within the pharmaceutical and biotech industries, including District Manager, Brand Manager, Managed Market Specialist, Contract Manager, andGovernment Account Manager. Mr. Hamilton was a Director of the Company from 2008 through March 2016. Aside from that provided above, Mr. Hamilton does not hold and has not held over the past five years any other directorships in any company with a class ofsecurities registered pursuant to Section 12 of the Exchange Act or subject to the requirements of Section 15(d) of the Exchange Act or any companyregistered as an investment company under the Investment Company Act of 1940. Gus D. Halas Mr. Halas joined our company as a Director on August 7, 2014. Mr. Halas has served as CEO of several companies. He was Chief Executive Officer andPresident of the Central Operating Companies at Central Garden & Pet Company from April 2011 through May 2013 and currently serves as a consultant tothat Company. Mr. Halas was President and Chief Executive Officer of T-3 Energy Services, Inc. from May 2003 to March 2009 and also served as Chairmanof the Board of Directors from March 2004 to March 2009. From August 2001 to April 2003, Mr. Halas served as President and Chief Executive Officer ofClore Automotive, Inc. He also serves as a director for Triangle Petroleum Corp., Hooper Holmes, Inc., School Specialty, Inc., and Madelena Energy. Aside from that provided above, Mr. Halas does not hold and has not held over the past five years any other directorships in any company with a class ofsecurities registered pursuant to Section 12 of the Exchange Act or subject to the requirements of Section 15(d) of the Exchange Act or any companyregistered as an investment company under the Investment Company Act of 1940. Mr. Halas is qualified to serve on our Board of Directors because of his experience and expertise as an executive and a director with companies implementing“turnaround” strategies. 23  Jack Pinney Mr. Pinney joined our company as a Director on August 13, 2014. From 2007 to the present, Dr. Pinney has served as Team Physician to the Great LakesLoons baseball team in the LA Dodgers organization. From 2011 to the present, he has served as Medical Director for WellSport MidMichigan MedicalCenter. From 1992 to the present, he has served as Assistant Clinical Professor of Family Medicine for the Department of Family Medicine at Michigan StateUniversity College of Human Medicine. From 1992 to 2012, he served as Assistant Director for the Midland Family Practice Residency Program atMidMichigan Medical Center. Aside from that provided above, Dr. Pinney does not hold and has not held over the past five years any other directorships in any company with a class ofsecurities registered pursuant to Section 12 of the Exchange Act or subject to the requirements of Section 15(d) of the Exchange Act or any companyregistered as an investment company under the Investment Company Act of 1940. Dr. Pinney is qualified to serve on our Board of Directors because of his expertise medicine and prescription practices of physicians. Lynn Vos Ms. Vos has been chief executive officer of ghg | greyhealth group since 1994 and is a champion of using digital capabilities to improve the public health.Ms. Vos also serves on the board of nTelos Wireless, a NASDAQ listed company, the Jed Foundation, a leading nonprofit dedicated to protecting theemotional health of college students, and was a founding board member of MMRF, a pioneering cancer research foundation. Aside from that provided above, Ms. Vos does not hold and has not held over the past five years any other directorships in any company with a class ofsecurities registered pursuant to Section 12 of the Exchange Act or subject to the requirements of Section 15(d) of the Exchange Act or any companyregistered as an investment company under the Investment Company Act of 1940. Ms. Vos is qualified to serve on our Board of Directors because of her extensive executive skills in digital marketing and communications in the healthcareindustry. James Lang Mr. Lang joined our Board January 12, 2017. He brings us more than 25 years of experience in healthcare data, analytic, and technology enabled businessservices. Mr. Lang presently serves as an executive advisor to Water Street, a strategic private equity firm focused exclusively on building market-leadingcompanies in healthcare. He is also a director of BioVie, a development-stage company pioneering an innovative therapeutic that targets complications dueto liver cirrhosis. Mr. Lang previously served as CEO of Decision Resources Group, a leading healthcare research and consulting company providing high-value healthcareindustry analysis and insights, where he helped transform the company into an industry leader. Earlier, he was president of Strategic Decisions Group, apremier global strategy consultancy, and he expanded the life sciences practice and later sold it to IMS Health. He is an active private investor and advisorwith healthcare companies, including Boston Heart Diagnostics (acquired by Eurofins) and AlphalmpactRx (acquired by IMS Health). Aside from that provided above, Mr. Lang does not hold and has not held over the past five years any other directorships in any company with a class ofsecurities registered pursuant to Section 12 of the Exchange Act or subject to the requirements of Section 15(d) of the Exchange Act or any companyregistered as an investment company under the Investment Company Act of 1940. Mr. Lang is qualified to serve on our Board of Directors because of his extensive executive skills and background in the healthcare industry. 24  Brian Dillon Mr. Dillon is our Senior Vice President of Product and Strategy. Prior to joining OptimizeRx, he provided consulting services focused on the HiTECH (HealthInformation Technology) and pharmaceutical manufacturers services sector. Earlier in his career, he served as partner at AccelaPartners, a consulting firmfocused on Healthcare technology and the pharmaceutical industry. Prior to AccelaPartners, he served as regional vice president of Americas at Cegedim, aninternational healthcare software and services provider. Mr. Dillon was previously president and CEO of Intercon Systems. Before Intercon Systems, he was founder, president and CEO of Kelly Waldron, which waseventually acquired by McKessonHBOC Technology Solutions. Earlier, he served as vice president of sales at Walsh America, where he built the company’sclient base from three to 13 companies over three years with the company. Before Walsh America, he founded QuadROM Software Systems Inc. (NorthAmerican division absorbed into Walsh America). Dillon currently also serves as a director at Sofame Technologies Inc. and Visio Energy. Aside from that provided above, Mr. Dillon does not hold and has not held over the past five years any other directorships in any company with a class ofsecurities registered pursuant to Section 12 of the Exchange Act or subject to the requirements of Section 15(d) of the Exchange Act or any companyregistered as an investment company under the Investment Company Act of 1940. Douglas P. Baker Mr. Baker has served as our CFO since May 19, 2014. Mr. Baker is a Certified Public Account with a Master’s Degree in Business Administration. He hasextensive business experience including 9 years in public accounting with Plante Moran, 4 years as CFO of a privately held printing company, 5 years in avariety of divisional financial roles at MascoTech, Inc., a Fortune 500 automotive supplier, and from 1996 to 2014 as Chief Financial Officer of AppliedNanotech Holdings, Inc., (“APNT”) a publicly held nanotechnology research and licensing company. Mr. Baker was also a member of the Board of Directorsof APNT from 2006 through 2014. He is also currently Chairman of the Board of Total Health Care, Inc., a Detroit based Health Maintenance Organizationand has been a member of that Board since 1987. Aside from that provided above, Mr. Baker does not hold and has not held over the past five years any other directorships in any company with a class ofsecurities registered pursuant to Section 12 of the Exchange Act or subject to the requirements of Section 15(d) of the Exchange Act or any companyregistered as an investment company under the Investment Company Act of 1940. Directors Our bylaws authorize no less than three (3) and no more than Seven (7) Directors unless changed by the Board of Directors. The Investor Rights Agreementwe signed with WPP Luxembourg Gamma Three Sarl states that our Board of Directors shall consist of five (5) Directors, but that provision was waived byWPP in January 2017 and the Board was expanded at that time. We currently have six (6) Directors. Term of Office Our Directors are appointed for a one-year term to hold office until the next annual general meeting of our shareholders or until removed from office inaccordance with our bylaws. Our officers are appointed by our board of directors and hold office until removed by the board, subject to their respectiveemployment agreements. Significant Employees We have no significant employees other than our officers and directors. 25  Family Relationships There are no family relationships between or among the directors, executive officers or persons nominated or chosen by us to become directors or executiveofficers. Involvement in Certain Legal Proceedings During the past 10 years, none of our current directors, nominees for directors or current executive officers has been involved in any legal proceedingidentified in Item 401(f) of Regulation S-K, including: 1. Any petition under the Federal bankruptcy laws or any state insolvency law filed by or against, or a receiver, fiscal agent or similar officer was appointedby a court for the business or property of such person, or any partnership in which he or she was a general partner at or within two years before the time ofsuch filing, or any corporation or business association of which he or she was an executive officer at or within two years before the time of such filing; 2. Any conviction in a criminal proceeding or being named a subject of a pending criminal proceeding (excluding traffic violations and other minoroffenses); 3. Being subject to any order, judgment, or decree, not subsequently reversed, suspended or vacated, of any court of competent jurisdiction, permanently ortemporarily enjoining him or her from, or otherwise limiting, the following activities: i. Acting as a futures commission merchant, introducing broker, commodity trading advisor, commodity pool operator, floor broker, leverage transactionmerchant, any other person regulated by the Commodity Futures Trading Commission, or an associated person of any of the foregoing, or as an investmentadviser, underwriter, broker or dealer in securities, or as an affiliated person, director or employee of any investment company, bank, savings and loanassociation or insurance company, or engaging in or continuing any conduct or practice in connection with such activity; ii. Engaging in any type of business practice; or iii. Engaging in any activity in connection with the purchase or sale of any security or commodity or in connection with any violation of Federal or Statesecurities laws or Federal commodities laws; 4. Being subject to any order, judgment or decree, not subsequently reversed, suspended or vacated, of any Federal or State authority barring, suspending orotherwise limiting for more than 60 days the right of such person to engage in any type of business regulated by the Commodity Futures TradingCommission, securities, investment, insurance or banking activities, or to be associated with persons engaged in any such activity; 5. Being found by a court of competent jurisdiction in a civil action or by the SEC to have violated any Federal or State securities law, and the judgment insuch civil action or finding by the Commission has not been subsequently reversed, suspended, or vacated; 6. Being found by a court of competent jurisdiction in a civil action or by the Commodity Futures Trading Commission to have violated any Federalcommodities law, and the judgment in such civil action or finding by the Commodity Futures Trading Commission has not been subsequently reversed,suspended or vacated; 7. Being subject to, or a party to, any Federal or State judicial or administrative order, judgment, decree, or finding, not subsequently reversed, suspended orvacated, relating to an alleged violation of: i. Any Federal or State securities or commodities law or regulation; or 26  ii. Any law or regulation respecting financial institutions or insurance companies including, but not limited to, a temporary or permanent injunction, order ofdisgorgement or restitution, civil money penalty or temporary or permanent cease-and-desist order, or removal or prohibition order; or iii. Any law or regulation prohibiting mail or wire fraud or fraud in connection with any business entity; or 8. Being subject to, or a party to, any sanction or order, not subsequently reversed, suspended or vacated, of any self-regulatory organization (as defined inSection 3(a)(26) of the Exchange Act (15 U.S.C. 78c(a)(26))), any registered entity (as defined in Section 1(a)(29) of the Commodity Exchange Act (7 U.S.C.1(a)(29))), or any equivalent exchange, association, entity or organization that has disciplinary authority over its members or persons associated with amember. Director Independence The Board of Directors reviews the independence of our directors on the basis of standards adopted by the NASDAQ Stock Market (“NASDAQ”). As a part ofthis review, the Board of Directors considers transactions and relationships between our company, on the one hand, and each director, members of thedirector’s immediate family, and other entities with which the director is affiliated, on the other hand. The purpose of such a review is to determine which, ifany, of such transactions or relationships were inconsistent with a determination that the director is independent under NASDAQ rules. As a result of thisreview, the Board of Directors has determined that each of our directors other than Mr. Harrell and Mr. Febbo is an “independent director” within the meaningof applicable NASDAQ listing standards. Committees of the Board The Board of Directors has two standing committees to facilitate and assist the Board of Directors in the execution of its responsibilities: (1) Nominating andGovernance Committee; and (2) Compensation Committee. Each committee acts pursuant to a written charter adopted by the Board of Directors. Eachcommittee’s charter is available on our corporate website at http://www.optimizerx.com. All of the committees are comprised solely of non-employee,independent directors as defined by NASDAQ market listing standards. Nominating and Governance Committee The Board of Directors has established a Nominating and Governance Committee. The Committee is composed of Directors, Halas, Pinney, and Vos, and ischaired by Director Halas. The Nominating and Corporate Governance Committee has not held any meetings during the fiscal year ended December 31,2016, but will commence meetings in 2017. The Nominating and Corporate Governance Committee’s responsibilities, which are discussed in detail in itscharter, include the responsibility to: ●Develop qualifications and criteria for selecting and evaluating directors and nominees;●Consider and propose director nominees;●Make recommendations to the Board regarding Board compensation;●Make recommendations to the Board regarding Board committee memberships;●Develop and recommend to the Board corporate governance guidelines;●Facilitate an annual assessment of the performance of the Board and each of its standing committees;●Consider the independence of each director and nominee for director; and●Perform other functions or duties deemed appropriate by the Board. 27  Compensation Committee The Board of Directors has established a Compensation Committee. The Compensation Committee has not held any meetings during the fiscal year endedDecember 31, 2016, but will commence meetings in 2017. The Committee is composed of Directors, Halas, Pinney, and Lang, and is chaired by DirectorLang. The Compensation Committee’s responsibilities, which are discussed in detail in its charter, include the responsibility to: ●In consultation with our senior management, establish our general compensation philosophy and oversee the development and implementation ofour compensation programs;●Recommend the base salary, incentive compensation and any other compensation for our Chief Executive Officer to the Board of Directors andreview and approve the Chief Executive Officer’s recommendations for the compensation of all other officers of our company and its subsidiary;●Administer our incentive and stock-based compensation plans, and discharge the duties imposed on the Compensation Committee by the terms ofthose plans;●Review and approve any severance or termination payments proposed to be made to any current or former officer of our company;●Perform other functions or duties deemed appropriate by the Board of Directors. Audit Committee We do not have a separately-designated standing audit committee. The entire board of directors performs the functions of an audit committee, but no writtencharter governs the actions of the board of directors when performing the functions of that would generally be performed by an audit committee. The board ofdirectors approves the selection of our independent accountants and meets and interacts with the independent accountants to discuss issues related tofinancial reporting. In addition, the board of directors reviews the scope and results of the audit with the independent accountants, reviews with managementand the independent accountants our annual operating results, considers the adequacy of our internal accounting procedures and considers other auditingand accounting matters including fees to be paid to the independent auditor and the performance of the independent auditor. For the fiscal year ending December 31, 2016, the board of directors: 1.Reviewed and discussed the audited financial statements with management, and 2.Reviewed and discussed the written disclosures and the letter from our independent auditors on the matters relating to the auditor's independence. Based upon the board of directors’ review and discussion of the matters above, the board of directors authorized inclusion of the audited financial statementsfor the year ended December 31, 2016 to be included in this Annual Report on Form 10-K and filed with the Securities and Exchange Commission. Section 16(a) Beneficial Ownership Reporting Compliance Section 16(a) of the Exchange Act requires our directors and executive officers and persons who beneficially own more than ten percent of a registered classof the Company’s equity securities to file with the SEC initial reports of ownership and reports of changes in ownership of common stock and other equitysecurities of the Company. Officers, directors and greater than ten percent beneficial shareholders are required by SEC regulations to furnish us with copies ofall Section 16(a) forms they file. To the best of our knowledge based solely on a review of Forms 3, 4, and 5 (and any amendments thereof) received by us, nopersons have failed to file, on a timely basis, the identified reports required by Section 16(a) of the Exchange Act during fiscal year ended December 31,2016, other than Mr. Harrell failed to file a Form 4 for restricted stock that he disposed of in February 2016 and Mr. Pinney filed a Form 4 late by 4 days inDecember 2016. Code of Ethics As of December 31, 2016, we had not adopted a Code of Ethics. We felt, until recently, the small number of individuals comprising our board andmanagement did not warrant the adoption of a Code of Ethics. Now that we have expanded our board and our increasing the size of our organization, weintend to adopt a Code of Ethics in the near future Board Meeting. 28  Item 11. Executive Compensation The table below summarizes all compensation awarded to, earned by, or paid to our former or current executive officers for the fiscal years ended December31, 2016 and 2015. Name and principal position Year Salary ($) Bonus ($) Stock Awards ($) Option Awards ($) All Other Compensation($) (1) Total ($) David A. Harrell Chairman, Former CEO 20162015 185,646201,508 75,000 73,509 00 185,646350,017 William J. Febbo CEO, Director 2016 188,833 83,742 993,825 4,400 1,270,800 Terence J. Hamilton SVP of Sales 20162015 180,125165,000 60,29460,000 110,264 154,684 7,2050 402,308335,264 James Brooks Former SVP of Business Development 2016 185,000 0 232,290 3,700 420,990 Brian Dillon SVP 2016 114,983 30,729 77,342 3,700 226,754 Douglas P. Baker CFO 20162015 172,500143,750 44,84760,000 010,668 6,9000 224,247214,418 Narrative Disclosure to the Summary Compensation Table (1)Amounts reflected in All Other Compensation column represent employer matching contributions to the Company’s retirement plan, on the samebasis as for all employees. Mr. Harrell was CEO in 2015 and through February 21, 2016, at which point he moved to a consulting role. He remained an employee through December 31,2016. Effective January 1, 2017, he became an outside consultant and will be compensated at a rate of $15,000 per month through September 30, 2017. Inaddition, the Board approved an additional payout of $720,415 in 2016 to retire 595,384 shares due and owing to Mr. Harrell, awarded in prior years, but notyet issued as of that date. That payment is not reflected in this table in 2016, however the share awards were reflected in 2015 and prior years as they weregranted. Mr. Febbo joined the Company as CEO on February 22, 2016. His employment contract calls for an annual base salary of $220,000. In addition, he is eligibleto participate in the Company’s executive bonus plan with a target bonus of 50% of his annual salary. He is also eligible for vacation, sick days, insurance, toparticipate in the Company’s 401k plan, and other benefits covering all employees. In March 2017, Mr. Febbo’s annual salary was adjusted to $250,000 peryear, retroactive to January 1, 2017 by the compensation of the Board of Directors. No formal contract amendment was signed. Under the terms of hiscontract, he was also granted 1,500,000 stock options, exercisable at a price of $1.07, and vesting annually over a period of 5 years. Mr. Febbo’s contractcalls for 12 months of severance if he is terminated without cause. On June 27, 2016, Mr. Hamilton’s signed a new employment agreement calling for a base salary of $181,650. In addition, he is eligible to participate in theCompany’s executive bonus plan with a target bonus of 40% of his annual salary. He is also eligible for vacation, sick days, insurance, to participate in theCompany’s 401k plan, and other benefits covering all employees. In March 2017, Mr. Hamilton’s annual salary was adjusted to $200,000 per year,retroactive to January 1, 2017 by the compensation committee of the Board of Directors. No formal contract amendment was signed. Mr. Hamilton’s contractalso calls for 12 months of severance if he is terminated without cause. Mr. Hamilton was also granted 200,000 discretionary options in 2016, exercisable at aprice of $1,15, and vesting annually over a period of two years. 29  Mr. Brooks joined the Company as Senior Vice President of Business Development on January 4, 2016. On November 30, 2016, Mr. Brooks moved to aconsulting role with our company. Effective on that date, Mr. Brooks was no longer our Senior Vice President of Business Development. We agreed to pay allcompensation and reimbursable expenses through December 31, 2016. His employment contract called for an annual base salary of $185,000. In addition, hewas eligible to participate in the Company’s executive bonus plan with a target bonus of 40% of his annual salary. He is also eligible for vacation, sick days,insurance, to participate in the Company’s 401k plan, and other benefits covering all employees. Under the terms of his contract, he was also granted 300,000performance based stock options, exercisable at a price of $1.32, none of which vested. Mr. Dillon joined the Company as Senior Vice President of Product and Strategy on May 18, 2016. His employment contract calls for an annual base rate of$185,000. In addition, he is eligible to participate in the Company’s executive bonus plan with a target bonus of 30% of his annual salary. He is also eligiblefor vacation, sick days, insurance, and other benefits covering all employees. Under the terms of his contract, he was also granted 100,000 stock options,exercisable at a price of $1.15, and vesting annually over a period of 2 years. Mr. Dillon’s contract calls for 6 months of severance if he is terminated withoutcause. On June 27, 2016, Mr. Baker signed a new employment agreement calling for a base salary of $180,000. In addition, he is eligible to participate in theCompany’s executive bonus plan with a target bonus of 30% of his annual salary. He is also eligible for vacation, sick days, insurance, to participate in theCompany’s 401k plan, and other benefits covering all employees. In March 2017, Mr. Baker’s annual salary was adjusted to $200,000 per year, retroactive toJanuary 1, 2017, by the compensation committee of the Board of Directors. No formal contract amendment was signed. Mr. Baker’s contract calls for 6months of severance if he is terminated without cause. 30  Outstanding Equity Awards at Fiscal Year-End The table below summarizes all unexercised options, stock that has not vested, and equity incentive plan awards for each named executive officers as ofDecember 31, 2016. OUTSTANDING EQUITY AWARDS AT FISCAL YEAR-ENDOPTION AWARDS STOCK AWARDS Name Number of Securities Underlying Unexercised Options (#) Exercisable Number of Securities Underlying Unexercised Options (#) Unexercisable Equity Incentive Plan Awards: Number of Securities Underlying Unexercised Unearned Options (#) Option Exercise Price ($) Option Expiration Date Number of Shares or Units of Stock That Have Not Vested (#) Market Value of Shares or Units of Stock That Have Not Vested ($) Equity Incentive Plan Awards: Number of Unearned Shares, Units or Other Rights That Have Not Vested (#) Equity Incentive Plan Awards: Market or Payout Value of Unearned Shares, Units or Other Rights That Have Not Vested (#) Will Febbo 0 1,500,000 $1.07 2/21/21 Douglas Baker 100,000 0 $1.05 5/19/19 50,000 50,000 $1.05 6/24/20 Terry Hamilton 0 200,000 $1.15 7/28/16 Brian Dillon 0 100,000 $1.15 7/28/16 Director Compensation The table below summarizes all compensation of our directors as of December 31, 2016: Name Fees Earned orPaid in Cash ($) Stock Awards($) Option Awards($) All OtherCompensation($) Total ($) Gus D. Halas 25,000 25,688 50,688 Jack Pinney 25,000 25,688 50,688 Lynn Vos -0- -0- -0- Narrative Disclosure to the Director Compensation Table Pursuant to our Director Compensation Plan, independent directors (“Outside Directors”) shall receive (a) a $25,000 annual cash retainer, payable in equalquarterly installments, and (b) reimbursement for expenses related to Board meeting attendance and any committee participation. Directors are expected toattend four meetings per year as well as spend an additional 10 – 20 hours per month on company matters. In addition, Outside Directors shall receive 25,000shares of Common Stock, payable in equal quarterly installments, which shall vest immediately. Directors that are also employees of our company shall notreceive additional compensation for serving on the Board. Both the cash retainer and stock awards are prorated for partial quarters of service when a newDirector joins the Board. 31  Item 12. Security Ownership of Certain Beneficial Owners and Management and Related CERTAIN BENEFICIAL OWNERS The following table sets forth the beneficial ownership by each person, other than executive officers and directors, known to us to beneficially own 5% ormore of our outstanding common stock as of March 1, 2017. This information is based on public filings as of March 1, 2017. For the purposes of this AnnualReport on Form 10-K, beneficial ownership of securities is defined in accordance with the rules of the SEC to mean generally the power to vote or dispose ofsecurities, regardless of any economic interest therein, including any such security that the person has the right to acquire within 60 days after such date. More Than 5% Beneficial Owners: Name and Address Common SharesOwned Percentage of Class Common WPP PLC(1)27 Farm StreetLondon, United KingdomW1J 5RJ 6,011,106 20.2%Common Wolverine Flagship FundTrading Limited(2)175 W Jackson Blvd, 3rd FlrChicago, IL 60604 2,158,360 7.3%Common Harvey L. Poppel(3)110 El MirasolPalm Beach, FL 33480 2,569,044 8.6%Common Ronald L. Chez(4)55 East Monroe Street, Suite 3700Chicago, IL 60603 2,721,976 9.2%Common Goldman Capital Management(5)767 Third Avenue, 25th FloorNew York, NY 10017 1,532,394 5.2% (1)As stated in a Schedule 13D filed with the Securities and Exchange Commission on October 2, 2015.(2)As stated in a Schedule 13G/A filed with the Securities and Exchange Commission on February 13, 2017.(3)As stated in a Schedule 13G filed with the Securities and Exchange Commission on January 17, 2017.(4)As stated in a Schedule 13D/A filed with the Securities and Exchange Commission on October 27, 2015.(5)As stated in a Schedule 13G filed with the Securities and Exchange Commission on October 24, 2014. 32  SECURITY OWNERSHIP OF MANAGEMENT Set forth below is certain information with respect to beneficial ownership of our common stock as of March 11, 2017, by each director, each executiveofficer, and by the directors and executive officers as a group. Unless otherwise indicated, each person or member of the group listed has sole voting andinvestment power with respect to the shares of common stock listed. Name(1) OptionsIncludedin BeneficialOwnership (2) CommonSharesOwned Common StockBeneficialOwnership Percentageof Class David A. Harrell 0 2,590,750 2,590,750 8.7%William J. Febbo 300,000 44,000 344,000 * Terence J. Hamilton 0 380,413 380,413 1.3%Lynn Vos 0 0 0 * Brian Dillon 0 0 0 * Douglas P. Baker 150,000 40,000 190,000 * Gus D. Halas 0 61,269 61,269 * Jack Pinney 0 787,329 787,329 2.6%James Lang 0 0 0 * All Executive Officers and Directors as a group (6 persons) 450,000 3,903,761 4,353,761 14.7% *Less than 1%(1)The address of each person named in this table is c/o OptimizeRx Corp., 400 Water Street, Suite 200, Rochester, MI 48307.(2)This column lists shares that are subject to options exercisable within sixty (60) days of March 1, 2017, and are included in common stock beneficialownership pursuant to Rule 13d-3(d)(1) of the Exchange Act. Item 13. Certain Relationships and Related Transactions, and Director Independence Other than described below or the transactions described under the heading “Executive Compensation” (or with respect to which such information is omittedin accordance with SEC regulations), there have not been, and there is not currently proposed, any transaction or series of similar transactions to which wewere or will be a participant in which the amount involved exceeded or will exceed the lesser of $120,000 or one percent of the average of our total assets atyear-end for the last two completed fiscal years, and in which any director, executive officer, holder of 5% or more of any class of our capital stock or anymember of the immediate family of any of the foregoing persons had or will have a direct or indirect material interest. During 2016, we had billings of $2,613,942 to agencies that are part of the WPP group and recognized revenue of $1,542,411 related to those billings. As ofDecember 31, 2016, we have receivables included in trade receivables on the balance sheet of $1,108,585 from WPP agencies and amounts due to WPPagencies included in revenue share payable of $127,458 as of December 31, 2016. In addition, we purchased of $190,686 from WPP agencies in 2016 andhad amounts owed related to those services of $12,600 in accounts payable at December 31, 2016. During 2015, we had billings of $420,503 to agencies that are part of the WPP group and recognized revenue of $178,855 related to those billings. As ofDecember 31, 2015, we have receivables included in trade receivables on the balance sheet of $381,125 from WPP agencies and amounts due to WPPagencies included in revenue share payable of $37,803 as of December 31, 2015. 33  On May 9, 2016, we entered into a Separation Agreement and Release with Mr. David Harrell that granted us a standard release of employment claims inconsideration for, among other things, the stock payout of $720,415 to Mr. Harrell. On the same date, we entered into a Corporate Consulting Agreement with Mr. Harrell that sets forth the terms his continued relationship with our company.He remained our employee through May 31, 2016 and the Corporate Consulting Agreement went effective as of June 1, 2016. Under the terms of thisagreement, Mr. Harrell agreed to consult for our company for a period of 16 months and he will receive a monthly payment of $15,000, with the potential forup to $54,000 in additional bonus payments during the term of the agreement. This agreement also calls for insurance benefits for seven months. Finally, theagreement contains a Consultant Confidentiality, Invention Assignment and Non-Compete Agreement that contains restrictive covenants that include a oneyear non-compete following the completion of Mr. Harrell’s 18 months of consulting, and an inventions assignment clause during the term of his consultingrelationship. On September 24, 2015, we entered into an Investor Rights Agreement with WPP (the “Rights Agreement”), pursuant to which we agreed to the following: ●Demand Registration Rights. We granted WPP registration rights for its shares and any securities acquired in connection with an Amended andRestated Co-Marketing Agreement (described below) after a period of two years.●Inspection Rights. So long as WPP owns not less than 25% of the shares, we granted WPP an annual right to inspect our books and records.●Observer Rights. So long as WPP owns not less than 25% of the shares, we will allow WPP to choose a representative to attend our board meetings asa nonvoting observer.●Board Seat. So long as WPP owns not less than 25% of the shares, we agreed to appoint a nominee of WPP as a member of our board of directors. Wealso agreed to a five member Board of Directors provided that it is not prohibited by the rules and regulations of an exchange that we trade on. Wealso agreed to enter into an indemnity agreement with the nominee.●Budget Review. So long as WPP owns not less than 25% of the shares, we agreed to review our budget plans with WPP’s nominee prior to submissionto the Board of Directors, at the request of WPP.●Right of First Refusal. We agreed that, in the event that we propose to sell new securities, we will first offer such new securities to WPP.●Special Approval Matters. So long as WPP owns not less than 25% of the shares, and provided that it is not prohibited by the rules and regulationsof an exchange that we trade on, we agreed that 80% Board approval will be required for certain decisions, including:○the incurrence of any indebtedness in excess of $1.5 million in the aggregate during any fiscal year○the sale, transfer or other disposition of all or substantially all of our assets;○the acquisition of any assets or properties (in one or more related transactions) for cash or otherwise for an amount in excess of $1.5 million inthe aggregate during any fiscal year;○capital expenditures in excess of $1.5 million individually (or in the aggregate if related to an integrated program of activities) or in excess of$1.5 million in the aggregate during any fiscal year;○making, or permitting any subsidiary to make, loans to, investments in, or purchasing, or permitting any subsidiary to purchase, any stock orother securities in another corporation, joint venture, partnership or other entity;○the commencement or settlement of any lawsuit, arbitration or other legal proceeding related to our intellectual property or involving anamount in controversy greater than $1.5 million; and○the issuance of new securities, except for securities issued under an equity incentive plan and any issuance of common stock to vendors,advisors, financial institutions, suppliers or joint ventures that do not exceed, individually or in the aggregate 5% of our then issued andoutstanding capital stock. 34  On September 24, 2015, we amended and restated an existing Co-Marketing Agreement with Grey Healthcare Group, LLC (“GHG”) an affiliate of WPP (the“Amended and Restated Co-Marketing Agreement”). The Amended and Restated Co-Marketing Agreement was amended to give the GHG the option toreceive all or part of the compensation due under the agreement in shares of our common stock. Shares issuable under the Amended and Restated Co-Marketing Agreement will be issued to WPP or any other affiliate of GHG designated in writing by GHG at the following rates: ●Until June 30, 2016, we will issue the number of shares of common stock equal to GHG’s share of net revenues received for sales of new services toGHG or Company clients (“GHG Net Revenues”) divided by $0.7875. ●After June 30, 2016, we will issue the number of shares of common stock equal to the GHG Net Revenues divided by a price equal to 80% multipliedby the average trading price of one share of common stock during the 30 trading day period immediately prior to the date of the most recentstatement of GHG Net Revenues set forth by the Company. Item 14. Principal Accounting Fees and Services Below is the table of Audit Fees (amounts in US$) billed by our auditor in connection with the audit of the Company’s annual financial statements andreview of the quarterly financial statements for the years ended: Financial Statements for theYear Ended December 31 Audit Services Audit RelatedFees Tax Fees Other Fees 2016 $43,500 $0 $3,000 $0 2015 $36,000 $0 $3,000 $0 35  PART IV Item 15. Exhibits, Financial Statements Schedules (a) Financial Statements and Schedules The following financial statements and schedules listed below are included in this Form 10-K.Financial Statements (See Item 8) (b) Exhibits ExhibitNumber Description3.1 Articles of Incorporation of OptimizeRx Corporation (the “Company”)13.2 Amended and Restated Bylaws of the Company23.3 Certificate of Designation, filed on September 5, 2008 with the Secretary of State of the State of Nevada by the Company13.4 Certificate of Designation, filed on June 3, 2010 with the Secretary of State of the State of Nevada by the Company310.1 Securities Purchase Agreement410.2 Registration Rights Agreement410.3 Investor Agreement410.4 Warrant Agreement510.5 Warrant Agreement510.6 Stock Purchase Agreement, dated September 24, 2015610.7 Investor Rights Agreement, dated September 24, 2015610.8 Indemnity Agreement, dated September 24, 2015610.9 Employment Agreement between the Company and William Febbo, dated February 12, 2016710.10 Separation Agreement, Corporate Consulting Agreement and Confidentiality Agreement between the Company and David Harrell dated May5, 2016810.11 Agreement between the Company and Brian Dillon, dated June 22, 2016910.12 Employment Agreement between the Company and Terry Hamilton, dated June 27, 2016910.13 Employment Agreement between the Company and David Baker, dated June 27, 2016921.1 List of Subsidiaries131.1** Certification of Chief Executive Officer pursuant to Securities Exchange Act Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 ofthe Sarbanes-Oxley Act of 200231.2** Certification of Chief Financial Officer pursuant to Securities Exchange Act Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 ofthe Sarbanes-Oxley Act of 200232.1** Certification of Chief Executive Officer and Chief Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906of the Sarbanes-Oxley Act of 2002101** The following materials from the Company’s Annual Report on Form 10-K for the year ended December 31, 2016 formatted in ExtensibleBusiness Reporting Language (XBRL). 1Incorporated by reference to the Form S-1, filed by the Company with the Securities and Exchange Commission on November 12, 2008.2Incorporated by reference to the Form 8-K, filed by the Company with the Securities and Exchange Commission on July 16, 2010.3Incorporated by reference to the Form 8-K, filed by the Company with the Securities and Exchange Commission on June 11, 2010.4Incorporated by reference to the Form 8-K, filed by the Company with the Securities and Exchange Commission on March 18, 2014.5Incorporated by reference to the Form S-1/A filed by the Company with the Securities and Exchange Commission on May 12, 2014.6Incorporated by reference to the Form 8-K, filed by the Company with the Securities and Exchange Commission on September 30, 2015.7Incorporated by reference to the Form 8-K, filed by the Company with the Securities and Exchange Commission on February 19, 2016.8Incorporated by reference to the Form 10-Q, filed by the Company with the Securities and Exchange Commission on May 9, 2016.9Incorporated by reference to the Form 8-K, filed by the Company with the Securities and Exchange Commission on June 27, 2016. **Provided herewith 36  SIGNATURES Pursuant to the requirements of Section 13 or 15(d) of the Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by theundersigned, thereunto duly authorized. OptimizeRx Corporation By:/s/ William J. Febbo William FebboChief Executive Officer, Principal Executive Officer March 8, 2016 By:/s/ Douglas P. Baker Douglas P. Baker Title:Chief Financial Officer, Principal Financial Officer andPrincipal Accounting Officer Date:March 8, 2016 Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of the registrantand in the capacities and on the dates indicated. By:/s/ David Harrell David Harrell Title:Chairman and Director Date:March 8, 2016 By:/s/ William J. Febbo William J. Febbo Title:Director Date:March 8, 2016 By:/s/ James Lang James Lang Title:Director Date:March 8, 2016 By:/s/ Gus D. Halas Gus D. Halas Title:Director Date:March 8, 2016 By:/s/ Jack Pinney Jack Pinney Title:Director Date:March 8, 2016 By:/s/ Lynn Vos Lynn Vos Title:Director Date:March 8, 2016 37 Exhibit 31.1 CERTIFICATIONS I, William J. Febbo, certify that; 1.I have reviewed this annual report on Form 10-K for the year ended December 31, 2016 of OptimizeRx Corp (the “registrant”); 2.Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make thestatements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report; 3.Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects thefinancial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report; 4.The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in ExchangeAct Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for theregistrant and have: a.Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensurethat material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities,particularly during the period in which this report is being prepared; b.Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under oursupervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for externalpurposes in accordance with generally accepted accounting principles; c.Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectivenessof the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and d.Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscalquarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect,the registrant’s internal control over financial reporting; and 5.The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to theregistrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions): a.All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonablylikely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and b.Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control overfinancial reporting. Date: March 8, 2017 /s/ William J. Febbo By:William J. Febbo Title:Chief Executive Officer, Principal Executive Officer Exhibit 31.2 CERTIFICATIONS I, Douglas P. Baker, certify that; 1.I have reviewed this annual report on Form 10-K for the year ended December 31, 2016 of OptimizeRx Corp (the “registrant”); 2.Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make thestatements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report; 3.Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects thefinancial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report; 4.The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in ExchangeAct Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for theregistrant and have: a.Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensurethat material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities,particularly during the period in which this report is being prepared; b.Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under oursupervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for externalpurposes in accordance with generally accepted accounting principles; c.Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectivenessof the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and d.Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscalquarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect,the registrant’s internal control over financial reporting; and 5.The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to theregistrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions): a.All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonablylikely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and b.Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control overfinancial reporting. Date: March 8, 2017 /s/ Douglas P. Baker By:Douglas P. Baker Title:Chief Financial Officer, Principal Financial Officerand Principal Accounting Officer Exhibit 32.1 CERTIFICATION OF CHIEF EXECUTIVE OFFICER ANDCHIEF FINANCIAL OFFICERPURSUANT TO18 U.S.C. SECTION 1350,AS ADOPTED PURSUANT TOSECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 In connection with the annual Report of OptimizeRx Corp (the “Company”) on Form 10-K for the year ended December 31, 2016 filed with the Securitiesand Exchange Commission (the “Report”), I, William J. Febbo, Chief Executive Officer of the Company, and I, Douglas P. Baker, certify, pursuant to 18U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that: 1.The Report fully complies with the requirements of Section 13(a) of the Securities Exchange Act of 1934; and 2.The information contained in the Report fairly presents, in all material respects, the consolidated financial condition of the Company as of the datespresented and the consolidated result of operations of the Company for the periods presented. By:/s/ William J. Febbo Name:William J. Febbo Title:Chief Executive Officer, Principal Executive Officer Date:March 8, 2017 By:/s/ Doug Baker Name:Doug Baker Title:Chief Financial Officer, Principal Financial Officerand Principal Accounting Officer Date:March 8, 2017 This certification has been furnished solely pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

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